# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Csm1_B PF18211.1 KXS93375.1 - 0.092 12.6 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Csm1 subunit domain B MFS_1 PF07690.16 KXS93382.1 - 2.5e-26 92.5 19.7 2.5e-26 92.5 19.7 2.2 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS93382.1 - 1.2e-10 40.8 0.1 1.2e-10 40.8 0.1 2.5 3 1 1 4 4 4 1 Sugar (and other) transporter Glyco_hydro_16 PF00722.21 KXS93420.1 - 9.5e-07 28.5 0.1 3.2e-06 26.7 0.1 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 KXS93420.1 - 0.00026 19.5 0.1 0.0062 15.0 0.1 2.0 1 1 1 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) SUIM_assoc PF16619.5 KXS93447.1 - 0.97 9.6 14.8 6.5 6.9 9.2 3.1 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF445 PF04286.12 KXS93447.1 - 1.1 9.0 5.4 1.7 8.4 5.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF445) UBN_AB PF14075.6 KXS93451.1 - 0.02 14.6 1.2 0.033 13.9 1.2 1.3 1 0 0 1 1 1 0 Ubinuclein conserved middle domain Spt20 PF12090.8 KXS93451.1 - 0.033 13.8 1.4 0.042 13.5 1.4 1.1 1 0 0 1 1 1 0 Spt20 family Roughex PF06020.11 KXS93451.1 - 0.16 11.0 7.3 0.22 10.6 7.3 1.2 1 0 0 1 1 1 0 Drosophila roughex protein CDC45 PF02724.14 KXS93451.1 - 0.41 8.9 7.8 0.49 8.6 7.8 1.1 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.11 KXS93451.1 - 0.58 9.7 6.0 0.68 9.5 6.0 1.2 1 0 0 1 1 1 0 PPP4R2 RRN3 PF05327.11 KXS93451.1 - 1.5 7.2 3.8 1.8 7.0 3.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Asparaginase_2 PF01112.18 KXS93451.1 - 3.9 6.4 5.1 1.1 8.2 0.8 1.9 2 0 0 2 2 2 0 Asparaginase Glyco_hydro_3_C PF01915.22 KXS93463.1 - 2.1e-43 148.7 0.0 3.7e-43 147.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXS93463.1 - 2.1e-39 135.8 0.0 3.1e-39 135.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXS93463.1 - 2.6e-22 78.7 0.1 5.2e-22 77.7 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Sec10 PF07393.11 KXS93465.1 - 1.8e-148 496.1 0.0 3.2e-148 495.3 0.0 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box PF00646.33 KXS93465.1 - 1.8e-06 27.7 0.1 4e-06 26.6 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXS93465.1 - 3.2e-06 26.9 0.6 8e-06 25.7 0.1 1.9 2 0 0 2 2 2 1 F-box-like DUF1690 PF07956.11 KXS93465.1 - 0.2 12.1 1.8 12 6.4 0.0 3.2 3 0 0 3 3 3 0 Protein of Unknown function (DUF1690) Pkinase PF00069.25 KXS93469.1 - 1.4e-32 113.1 0.0 7.3e-32 110.8 0.0 2.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS93469.1 - 1.7e-10 40.6 0.0 1.3e-09 37.7 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase XPA_C PF05181.12 KXS93469.1 - 0.019 14.9 0.3 0.045 13.7 0.0 1.7 2 0 0 2 2 2 0 XPA protein C-terminus APH PF01636.23 KXS93469.1 - 0.13 12.2 0.1 1.5 8.7 0.0 2.5 2 1 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 KXS93469.1 - 0.21 11.2 0.0 0.35 10.4 0.0 1.2 1 0 0 1 1 1 0 RIO1 family EF-hand_4 PF12763.7 KXS93470.1 - 9.3e-35 118.7 0.0 1.2e-14 54.1 0.0 3.5 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 KXS93470.1 - 5.3e-09 36.4 0.0 0.0042 17.5 0.1 3.6 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 KXS93470.1 - 2.1e-06 26.9 4.2 2.4 7.9 0.0 5.6 6 0 0 6 6 5 1 EF hand EF-hand_8 PF13833.6 KXS93470.1 - 3.3e-05 23.7 0.0 2.4 8.0 0.0 4.8 5 0 0 5 5 5 1 EF-hand domain pair UBA PF00627.31 KXS93470.1 - 0.00012 21.9 0.0 0.00025 20.9 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_6 PF13405.6 KXS93470.1 - 0.00049 19.8 0.2 8.2 6.7 0.1 5.2 5 0 0 5 5 5 0 EF-hand domain Tup_N PF08581.10 KXS93470.1 - 0.014 15.7 18.2 0.027 14.8 7.6 2.8 2 1 0 2 2 2 0 Tup N-terminal FPP PF05911.11 KXS93470.1 - 0.061 11.5 25.1 0.098 10.8 25.1 1.2 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil CCDC144C PF14915.6 KXS93470.1 - 0.11 11.5 32.5 0.17 11.0 32.5 1.1 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region MscS_porin PF12795.7 KXS93470.1 - 0.41 10.2 50.0 0.11 12.0 21.8 2.4 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain HBS1_N PF08938.10 KXS93470.1 - 0.54 10.6 0.0 0.54 10.6 0.0 2.7 3 0 0 3 3 3 0 HBS1 N-terminus MAD PF05557.13 KXS93470.1 - 0.56 8.5 31.1 0.93 7.8 31.1 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein Spc7 PF08317.11 KXS93470.1 - 0.65 8.8 38.7 0.31 9.9 23.2 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein CALCOCO1 PF07888.11 KXS93470.1 - 1.1 8.1 33.2 1.6 7.5 33.2 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF3584 PF12128.8 KXS93470.1 - 1.1 6.7 32.7 1.8 5.9 32.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ATG16 PF08614.11 KXS93470.1 - 1.1 9.5 42.3 0.57 10.4 16.1 3.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) GAS PF13851.6 KXS93470.1 - 1.7 7.9 37.9 0.18 11.1 19.6 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 KXS93470.1 - 1.7 8.7 18.8 1.1 9.3 9.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Macoilin PF09726.9 KXS93470.1 - 3.7 6.0 32.1 0.21 10.1 23.9 2.3 2 0 0 2 2 2 0 Macoilin family SOGA PF11365.8 KXS93470.1 - 4.4 8.5 22.5 0.85 10.8 9.4 2.8 1 1 2 3 3 3 0 Protein SOGA TMF_TATA_bd PF12325.8 KXS93470.1 - 5.6 7.2 34.1 0.21 11.8 5.7 3.3 1 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding V_ATPase_I PF01496.19 KXS93470.1 - 6.5 4.5 22.3 2.3 6.0 19.8 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-F_leu_zip PF10473.9 KXS93470.1 - 9.2 6.3 34.6 0.81 9.7 15.0 2.4 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Syja_N PF02383.18 KXS93475.1 - 2.1e-77 260.6 0.0 2.8e-77 260.2 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 KXS93475.1 - 1.1e-07 31.6 0.1 2.2e-07 30.7 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family FAA_hydrolase PF01557.18 KXS93477.1 - 2.7e-58 197.2 0.0 3e-58 197.1 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Rtf2 PF04641.12 KXS93483.1 - 1.8e-56 191.4 4.2 2.1e-56 191.2 4.2 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.8 KXS93483.1 - 4.5e-06 26.4 0.0 0.00012 21.8 0.0 2.4 1 1 1 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 KXS93483.1 - 0.043 14.0 0.0 0.13 12.5 0.0 1.8 1 0 0 1 1 1 0 U-box domain AbiEi_3_N PF17194.4 KXS93483.1 - 0.046 13.7 0.2 0.55 10.3 0.0 2.4 2 1 1 3 3 3 0 Transcriptional regulator, AbiEi antitoxin N-terminal domain zf-RING_5 PF14634.6 KXS93483.1 - 0.086 12.8 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXS93483.1 - 0.12 12.4 0.6 0.36 10.9 0.2 2.0 2 0 0 2 2 2 0 RING-type zinc-finger Fumble PF03630.14 KXS93485.1 - 3e-140 467.1 0.4 3.8e-140 466.8 0.4 1.1 1 0 0 1 1 1 1 Fumble Fumble PF03630.14 KXS93486.1 - 3e-140 467.1 0.4 3.8e-140 466.8 0.4 1.1 1 0 0 1 1 1 1 Fumble Fumble PF03630.14 KXS93487.1 - 3e-140 467.1 0.4 3.8e-140 466.8 0.4 1.1 1 0 0 1 1 1 1 Fumble PBP1_TM PF14812.6 KXS93496.1 - 0.028 14.8 3.8 0.048 14.0 3.8 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-C2H2 PF00096.26 KXS93496.1 - 0.063 13.8 0.9 5.8 7.6 0.1 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type DNA_pol_phi PF04931.13 KXS93496.1 - 0.093 10.8 5.0 0.12 10.4 5.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi zf-C2H2_6 PF13912.6 KXS93496.1 - 0.14 12.2 0.3 0.28 11.2 0.3 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger Sporozoite_P67 PF05642.11 KXS93496.1 - 0.3 9.1 1.5 0.33 9.0 1.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF3500 PF12006.8 KXS93498.1 - 4e-08 33.1 0.0 5.8e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) Snurportin1 PF11538.8 KXS93498.1 - 0.018 15.2 0.5 0.042 14.0 0.5 1.6 1 0 0 1 1 1 0 Snurportin1 Shugoshin_N PF07558.11 KXS93500.1 - 0.0053 16.6 2.2 0.0053 16.6 2.2 4.6 4 1 1 5 5 5 2 Shugoshin N-terminal coiled-coil region TMF_TATA_bd PF12325.8 KXS93500.1 - 3.7 7.8 16.0 0.27 11.4 4.2 3.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding APG6_N PF17675.1 KXS93500.1 - 4.1 7.9 21.3 0.34 11.4 4.2 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region ZapB PF06005.12 KXS93500.1 - 4.8 7.7 23.3 12 6.4 1.5 3.5 1 1 1 2 2 2 0 Cell division protein ZapB FUSC PF04632.12 KXS93500.1 - 7.9 4.9 6.7 7.1 5.0 4.8 1.8 2 0 0 2 2 2 0 Fusaric acid resistance protein family Inositol_P PF00459.25 KXS93502.1 - 3.7e-37 128.3 0.0 5.6e-37 127.7 0.0 1.2 1 0 0 1 1 1 1 Inositol monophosphatase family adh_short PF00106.25 KXS93504.1 - 2.3e-11 43.5 0.0 3.4e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS93504.1 - 1e-07 31.8 0.0 1.4e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS93504.1 - 2.7e-07 30.7 0.0 4.5e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXS93504.1 - 0.026 13.6 0.1 0.36 9.9 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DUF1349 PF07081.11 KXS93505.1 - 3.3e-35 121.4 0.3 4e-35 121.1 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) HET PF06985.11 KXS93518.1 - 3.9e-25 88.9 7.4 4.2e-24 85.5 7.4 2.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Myf5 PF12232.8 KXS93518.1 - 2 9.2 6.4 13 6.6 4.6 2.6 2 0 0 2 2 2 0 Myogenic determination factor 5 Casc1 PF12366.8 KXS93519.1 - 0.057 12.9 0.3 0.064 12.8 0.3 1.2 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 BLM10_N PF16547.5 KXS93519.1 - 0.084 13.2 0.1 0.18 12.1 0.1 1.6 1 0 0 1 1 1 0 Proteasome-substrate-size regulator, N-terminal Macoilin PF09726.9 KXS93525.1 - 2.2 6.7 9.2 3.2 6.2 9.2 1.1 1 0 0 1 1 1 0 Macoilin family Metallopep PF12044.8 KXS93529.1 - 7.9e-173 575.0 0.0 1e-172 574.6 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.17 KXS93529.1 - 0.00023 21.1 0.0 0.00081 19.3 0.0 1.9 1 1 0 1 1 1 1 Jacalin-like lectin domain Peptidase_M10 PF00413.24 KXS93529.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Matrixin Reprolysin_5 PF13688.6 KXS93529.1 - 8.7 6.4 9.1 0.11 12.6 0.5 2.0 2 0 0 2 2 2 0 Metallo-peptidase family M12 Whi5 PF08528.11 KXS93530.1 - 3.6e-10 39.2 0.1 6.4e-10 38.4 0.1 1.4 1 0 0 1 1 1 1 Whi5 like Sugar_tr PF00083.24 KXS93531.1 - 1.2e-130 436.4 30.3 1.4e-130 436.2 30.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS93531.1 - 1.1e-23 83.7 34.8 5.3e-16 58.5 11.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-LYAR PF08790.11 KXS93532.1 - 1.5e-13 50.4 2.9 3.9e-13 49.0 2.9 1.8 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger FGGY_C PF02782.16 KXS93539.1 - 3.5e-50 170.5 0.1 5.4e-50 169.9 0.1 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KXS93539.1 - 2.2e-24 86.4 0.7 2.6e-21 76.3 0.1 3.1 3 1 0 3 3 3 2 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 KXS93539.1 - 0.00055 19.5 0.1 0.002 17.7 0.0 1.9 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family adh_short_C2 PF13561.6 KXS93540.1 - 3.2e-51 174.2 0.0 3.7e-51 174.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS93540.1 - 3.9e-46 157.0 0.1 8.4e-46 155.9 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KXS93540.1 - 1e-07 32.0 0.0 1.6e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS93540.1 - 8.9e-07 28.6 0.0 1.2e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KXS93540.1 - 2.9e-05 23.6 0.0 4.4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) 3HCDH_N PF02737.18 KXS93540.1 - 0.0045 16.9 0.0 0.039 13.8 0.0 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 KXS93540.1 - 0.033 13.6 0.1 0.053 12.9 0.1 1.5 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 KXS93540.1 - 0.095 13.0 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain RRM_1 PF00076.22 KXS93541.1 - 7.1e-11 41.8 0.0 1e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXS93541.1 - 0.058 13.0 0.0 0.09 12.4 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RAP1 PF07218.11 KXS93541.1 - 0.58 8.4 3.1 0.87 7.8 3.1 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SLH PF00395.20 KXS93542.1 - 0.014 15.3 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 S-layer homology domain Profilin PF00235.19 KXS93543.1 - 3.6e-51 172.7 0.7 4e-51 172.6 0.7 1.0 1 0 0 1 1 1 1 Profilin Aminotran_1_2 PF00155.21 KXS93544.1 - 0.00023 20.4 0.0 0.00085 18.6 0.0 1.9 2 1 0 2 2 2 1 Aminotransferase class I and II Pex14_N PF04695.13 KXS93544.1 - 0.13 12.9 0.3 0.34 11.6 0.3 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Metallophos PF00149.28 KXS93547.1 - 4.8e-10 40.3 0.1 6.8e-10 39.8 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXS93547.1 - 0.00036 20.8 0.0 0.0073 16.5 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain TFIIF_beta PF02270.15 KXS93547.1 - 0.071 13.2 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 TFIIF, beta subunit HTH domain DUF2656 PF10847.8 KXS93548.1 - 0.028 14.5 0.0 0.048 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2656) NAR2 PF16974.5 KXS93548.1 - 0.084 12.3 0.2 0.14 11.6 0.2 1.3 1 0 0 1 1 1 0 High-affinity nitrate transporter accessory AbiEii PF08843.11 KXS93549.1 - 0.084 12.8 0.1 2.4 8.1 0.1 2.1 1 1 0 1 1 1 0 Nucleotidyl transferase AbiEii toxin, Type IV TA system Sugar_tr PF00083.24 KXS93550.1 - 4.2e-88 296.2 26.9 4.8e-88 296.0 26.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS93550.1 - 2.9e-34 118.5 55.1 1.9e-31 109.3 27.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily SepZ PF06066.11 KXS93550.1 - 0.48 10.7 3.1 3.1 8.1 3.1 2.3 1 1 1 2 2 2 0 SepZ Pkinase PF00069.25 KXS93551.1 - 6e-13 48.8 0.0 9e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS93551.1 - 1.3e-05 24.6 0.0 2.1e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXS93551.1 - 1.4e-05 25.1 0.3 2.3e-05 24.4 0.3 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KXS93551.1 - 2.8e-05 23.6 0.0 4.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KXS93551.1 - 0.00088 18.9 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 KXS93551.1 - 0.0075 15.9 0.1 0.013 15.1 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.6 KXS93551.1 - 0.17 11.2 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Calici_PP_N PF08405.11 KXS93552.1 - 0.12 11.1 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Viral polyprotein N-terminal PIN_10 PF18478.1 KXS93554.1 - 0.12 12.6 0.1 0.26 11.5 0.1 1.5 1 0 0 1 1 1 0 PIN like domain MFS_1 PF07690.16 KXS93555.1 - 7.5e-34 117.2 39.0 1.8e-33 116.0 36.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily PMP1_2 PF08114.11 KXS93555.1 - 1.2 9.0 5.4 0.25 11.1 0.4 2.5 2 0 0 2 2 2 0 ATPase proteolipid family MFS_1 PF07690.16 KXS93556.1 - 7.5e-34 117.2 39.0 1.8e-33 116.0 36.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily PMP1_2 PF08114.11 KXS93556.1 - 1.2 9.0 5.4 0.25 11.1 0.4 2.5 2 0 0 2 2 2 0 ATPase proteolipid family MFS_1 PF07690.16 KXS93557.1 - 7.5e-34 117.2 39.0 1.8e-33 116.0 36.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily PMP1_2 PF08114.11 KXS93557.1 - 1.2 9.0 5.4 0.25 11.1 0.4 2.5 2 0 0 2 2 2 0 ATPase proteolipid family CCDC74_C PF14917.6 KXS93561.1 - 0.39 11.2 7.6 0.18 12.4 3.9 2.5 2 0 0 2 2 2 0 Coiled coil protein 74, C terminal CsgF PF10614.9 KXS93561.1 - 3 8.1 6.8 0.82 9.9 0.4 2.6 1 1 1 2 2 2 0 Type VIII secretion system (T8SS), CsgF protein SLT PF01464.20 KXS93565.1 - 3.6e-06 26.6 0.3 6.6e-06 25.8 0.3 1.4 1 0 0 1 1 1 1 Transglycosylase SLT domain Tetraspanin PF00335.20 KXS93565.1 - 0.052 13.3 0.1 0.095 12.4 0.1 1.4 1 0 0 1 1 1 0 Tetraspanin family SNARE PF05739.19 KXS93565.1 - 2.1 8.4 6.8 5.9 7.0 6.8 1.8 1 0 0 1 1 1 0 SNARE domain CFEM PF05730.11 KXS93566.1 - 9.6e-29 99.3 47.8 3.2e-10 39.9 9.1 3.7 3 0 0 3 3 3 3 CFEM domain zf-C2H2 PF00096.26 KXS93569.1 - 4.2e-13 48.9 27.7 1.9e-05 24.8 3.9 4.5 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS93569.1 - 1.4e-09 37.9 28.4 0.00048 20.7 2.8 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXS93569.1 - 1.5e-07 31.5 17.9 0.0091 16.4 0.7 4.5 4 0 0 4 4 4 3 Zinc-finger double domain zf-Di19 PF05605.12 KXS93569.1 - 0.0012 19.1 10.8 0.0014 18.9 0.4 2.5 1 1 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 KXS93569.1 - 0.0027 17.6 1.5 0.0027 17.6 1.5 3.7 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXS93569.1 - 0.011 16.0 7.7 0.29 11.5 0.7 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KXS93569.1 - 0.011 16.0 9.2 0.68 10.3 8.8 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 KXS93569.1 - 0.041 14.3 2.1 0.31 11.5 0.1 2.4 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_3rep PF18868.1 KXS93569.1 - 0.045 14.4 2.5 3.4 8.3 0.1 2.5 1 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats FOXP-CC PF16159.5 KXS93569.1 - 0.085 13.5 6.7 5.9 7.6 0.2 3.6 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-met PF12874.7 KXS93569.1 - 0.17 12.3 9.2 2.5 8.6 0.1 3.9 4 0 0 4 4 3 0 Zinc-finger of C2H2 type DUF1712 PF08217.11 KXS93569.1 - 0.23 9.9 0.1 0.34 9.3 0.1 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1712) Ogr_Delta PF04606.12 KXS93569.1 - 0.54 10.3 6.0 14 5.8 1.7 3.6 2 1 1 3 3 3 0 Ogr/Delta-like zinc finger zf-H2C2_5 PF13909.6 KXS93569.1 - 2.1 8.1 24.5 0.68 9.7 1.0 4.3 4 1 0 4 4 3 0 C2H2-type zinc-finger domain zf-BED PF02892.15 KXS93569.1 - 2.3 8.3 14.3 0.069 13.2 2.5 3.3 3 0 0 3 3 3 0 BED zinc finger zf-C2H2_11 PF16622.5 KXS93569.1 - 5.3 6.9 14.7 0.8 9.5 0.1 3.7 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 KXS93569.1 - 7.9 6.5 11.5 1.4 8.9 0.7 3.3 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-trcl PF13451.6 KXS93569.1 - 9.6 6.2 7.2 4.4 7.3 2.3 2.3 2 0 0 2 2 2 0 Probable zinc-ribbon domain zf-C2H2 PF00096.26 KXS93570.1 - 2.4e-05 24.5 43.0 0.0019 18.6 5.3 5.5 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KXS93570.1 - 2.5e-05 24.1 15.7 0.0044 17.0 0.3 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-Di19 PF05605.12 KXS93570.1 - 0.001 19.3 5.9 0.001 19.3 5.9 3.4 3 0 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KXS93570.1 - 0.0054 17.5 38.3 0.041 14.7 3.8 5.6 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2HE PF16278.5 KXS93570.1 - 0.096 13.2 0.1 0.096 13.2 0.1 3.5 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-HIT PF04438.16 KXS93570.1 - 1.4 8.8 4.5 17 5.4 0.8 2.6 2 0 0 2 2 2 0 HIT zinc finger zf-C2H2_2 PF12756.7 KXS93570.1 - 7.1 7.0 11.0 3.4 8.1 0.7 2.9 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) GPI-anchored PF10342.9 KXS93571.1 - 0.00016 22.4 0.2 0.00016 22.4 0.2 2.0 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family MSA-2c PF12238.8 KXS93571.1 - 0.073 13.1 4.1 0.1 12.6 4.1 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c Sporozoite_P67 PF05642.11 KXS93571.1 - 5.8 4.9 9.2 7.7 4.5 9.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RAP1 PF07218.11 KXS93571.1 - 6.6 4.9 5.4 8.5 4.5 5.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) F-box-like PF12937.7 KXS93572.1 - 0.0041 17.0 0.2 0.0089 15.9 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KXS93573.1 - 0.0039 17.1 0.2 0.0083 16.0 0.2 1.6 1 0 0 1 1 1 1 F-box-like AA_permease PF00324.21 KXS93574.1 - 1.8e-113 379.7 42.0 2.2e-113 379.4 42.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXS93574.1 - 8.5e-27 94.0 46.7 1.1e-26 93.7 46.7 1.0 1 0 0 1 1 1 1 Amino acid permease DUF2474 PF10617.9 KXS93574.1 - 0.027 14.3 0.1 0.092 12.6 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2474) DUF4577 PF15145.6 KXS93574.1 - 0.04 14.0 0.4 13 5.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4577) Adeno_E3B PF03376.14 KXS93574.1 - 0.13 12.5 0.9 0.35 11.1 0.1 2.2 2 0 0 2 2 2 0 Adenovirus E3B protein Abhydrolase_1 PF00561.20 KXS93576.1 - 2.1e-16 60.4 0.4 5.2e-16 59.1 0.4 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXS93576.1 - 4.9e-12 46.9 2.6 1.2e-10 42.4 2.6 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXS93576.1 - 2.5e-10 40.1 0.0 8.8e-10 38.2 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 KXS93576.1 - 0.0069 15.3 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.21 KXS93576.1 - 0.0078 15.7 0.1 0.019 14.5 0.1 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KXS93576.1 - 0.025 14.2 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 Putative esterase CHB_HEX PF03173.13 KXS93576.1 - 0.046 13.4 0.1 0.075 12.7 0.1 1.3 1 0 0 1 1 1 0 Putative carbohydrate binding domain AXE1 PF05448.12 KXS93576.1 - 0.047 12.4 0.0 0.071 11.8 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) p450 PF00067.22 KXS93577.1 - 5.9e-60 203.3 0.0 8.3e-60 202.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Sulfotransfer_4 PF17784.1 KXS93577.1 - 1.4e-53 182.0 0.0 2.7e-53 181.0 0.0 1.5 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KXS93577.1 - 0.0014 19.1 0.7 1.3 9.3 0.2 2.5 1 1 0 2 2 2 2 Sulfotransferase family FAD_binding_3 PF01494.19 KXS93580.1 - 4.9e-09 35.9 0.4 0.0003 20.1 0.0 2.7 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.14 KXS93580.1 - 0.00057 19.2 0.1 0.0052 16.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXS93580.1 - 0.00083 18.5 0.1 0.0014 17.8 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KXS93580.1 - 0.0013 18.2 0.0 0.0026 17.2 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 KXS93580.1 - 0.0013 18.4 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXS93580.1 - 0.0056 17.2 0.2 0.015 15.9 0.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXS93580.1 - 0.0067 16.6 0.1 0.013 15.7 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXS93580.1 - 0.091 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Ten1_2 PF15490.6 KXS93580.1 - 0.15 11.8 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Telomere-capping, CST complex subunit Peptidase_C48 PF02902.19 KXS93583.1 - 9.8e-05 22.3 0.6 0.00023 21.1 0.6 1.5 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Ribosomal_60s PF00428.19 KXS93583.1 - 3.2 8.4 16.3 3.7 8.2 14.6 2.1 1 1 0 1 1 1 0 60s Acidic ribosomal protein PRIMA1 PF16101.5 KXS93583.1 - 9.5 6.3 11.3 37 4.4 11.3 2.1 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 XRCC4 PF06632.12 KXS93585.1 - 0.023 13.5 0.2 0.036 12.9 0.2 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 PRIMA1 PF16101.5 KXS93585.1 - 1.9 8.5 7.2 3.7 7.6 7.2 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 KXS93585.1 - 2.1 7.7 4.6 3.7 7.0 4.6 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal COPI_assoc PF08507.10 KXS93589.1 - 8.8e-16 58.2 0.8 2e-07 31.1 0.0 2.1 2 0 0 2 2 2 2 COPI associated protein Tmemb_14 PF03647.13 KXS93589.1 - 0.095 13.4 1.5 0.18 12.6 1.4 1.5 1 1 0 1 1 1 0 Transmembrane proteins 14C YtpI PF14007.6 KXS93589.1 - 0.54 10.4 4.7 0.11 12.6 1.2 1.6 2 0 0 2 2 2 0 YtpI-like protein DUF308 PF03729.13 KXS93589.1 - 0.59 10.5 15.6 1.6 9.1 0.9 2.8 2 1 0 2 2 2 0 Short repeat of unknown function (DUF308) COPI_assoc PF08507.10 KXS93590.1 - 5.8e-31 107.2 2.0 6.2e-31 107.1 2.0 1.0 1 0 0 1 1 1 1 COPI associated protein IF-2B PF01008.17 KXS93591.1 - 2.3e-48 164.9 0.0 2.8e-48 164.6 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family GATA PF00320.27 KXS93593.1 - 7.7e-31 105.4 16.0 6.4e-16 57.7 3.7 2.7 2 0 0 2 2 2 2 GATA zinc finger ArfGap PF01412.18 KXS93593.1 - 3.1e-06 27.3 2.5 0.023 14.8 0.2 2.5 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf TF_Zn_Ribbon PF08271.12 KXS93593.1 - 1.4e-05 24.5 4.5 0.043 13.3 0.3 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding TDP43_N PF18694.1 KXS93593.1 - 0.00012 21.9 0.1 0.033 14.0 0.0 2.4 2 0 0 2 2 2 1 Transactive response DNA-binding protein N-terminal domain Zn-ribbon_8 PF09723.10 KXS93593.1 - 0.001 19.2 7.2 0.062 13.4 0.3 2.9 3 0 0 3 3 2 2 Zinc ribbon domain eIF-5_eIF-2B PF01873.17 KXS93593.1 - 0.015 15.2 5.4 1.6 8.6 0.7 2.5 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Auto_anti-p27 PF06677.12 KXS93593.1 - 0.039 14.1 9.4 0.95 9.7 0.6 2.7 3 0 0 3 3 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-Sec23_Sec24 PF04810.15 KXS93593.1 - 0.046 13.8 0.8 0.046 13.8 0.8 2.9 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger OrfB_Zn_ribbon PF07282.11 KXS93593.1 - 0.054 13.4 12.7 0.13 12.2 0.5 2.9 3 0 0 3 3 3 0 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.6 KXS93593.1 - 0.093 12.2 11.8 1.4 8.4 0.3 4.4 4 0 0 4 4 4 0 zinc-ribbon domain DZR PF12773.7 KXS93593.1 - 0.12 12.4 14.9 0.85 9.7 0.7 3.4 2 1 0 2 2 2 0 Double zinc ribbon HypA PF01155.19 KXS93593.1 - 1.7 8.7 8.2 1.6 8.7 0.3 2.8 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Jiv90 PF14901.6 KXS93593.1 - 2.4 8.3 5.3 11 6.3 0.2 2.5 2 0 0 2 2 2 0 Cleavage inducing molecular chaperone Rubredoxin_2 PF18073.1 KXS93593.1 - 2.7 7.8 9.1 46 3.8 0.1 4.4 4 0 0 4 4 4 0 Rubredoxin metal binding domain zf-CHY PF05495.12 KXS93593.1 - 3.6 8.1 8.2 2.7 8.5 0.4 2.9 3 0 0 3 3 3 0 CHY zinc finger GATase_6 PF13522.6 KXS93597.1 - 1.8e-14 54.1 0.0 3.5e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KXS93597.1 - 2.6e-12 46.8 0.0 5.1e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 KXS93597.1 - 2e-06 27.4 0.0 4.7e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 KXS93597.1 - 0.0058 15.6 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Cellulase PF00150.18 KXS93598.1 - 4.4e-50 170.7 4.9 5.8e-50 170.3 4.9 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) GATase_6 PF13522.6 KXS93599.1 - 1.9e-14 54.0 0.0 3.8e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KXS93599.1 - 2.8e-12 46.6 0.0 5.5e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 KXS93599.1 - 2.2e-06 27.3 0.0 5.1e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 KXS93599.1 - 0.0062 15.5 0.0 0.011 14.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Goodbye PF17109.5 KXS93599.1 - 0.19 12.2 0.0 0.48 10.9 0.0 1.6 1 0 0 1 1 1 0 fungal STAND N-terminal Goodbye domain Cellulase PF00150.18 KXS93600.1 - 4.4e-50 170.7 4.9 5.8e-50 170.3 4.9 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Mucin PF01456.17 KXS93601.1 - 0.0016 18.4 12.8 0.0016 18.4 12.8 1.9 2 0 0 2 2 2 1 Mucin-like glycoprotein Sporozoite_P67 PF05642.11 KXS93601.1 - 0.0087 14.2 5.0 0.01 14.0 5.0 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen DUF3439 PF11921.8 KXS93601.1 - 0.17 11.8 10.0 0.49 10.4 10.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) EXOSC1 PF10447.9 KXS93602.1 - 5.5e-20 72.0 1.0 1.7e-13 51.1 0.2 2.3 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 KXS93602.1 - 0.0029 17.4 0.0 0.007 16.1 0.0 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region PI3_PI4_kinase PF00454.27 KXS93604.1 - 1.6e-32 113.3 0.0 2.9e-31 109.2 0.0 2.4 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.8 KXS93604.1 - 1.3e-17 63.4 0.0 2.9e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 DUF4135 PF13575.6 KXS93604.1 - 0.027 13.8 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Radical_SAM PF04055.21 KXS93604.1 - 0.096 13.1 0.0 2.6 8.4 0.0 2.6 3 0 0 3 3 3 0 Radical SAM superfamily Epimerase PF01370.21 KXS93605.1 - 9.5e-10 38.3 0.1 0.00029 20.4 0.2 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXS93605.1 - 5.9e-08 32.8 0.1 8.5e-08 32.3 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXS93605.1 - 6e-08 32.5 0.4 3.1e-07 30.2 0.1 1.9 2 0 0 2 2 2 1 NmrA-like family Semialdhyde_dh PF01118.24 KXS93605.1 - 4.5e-05 23.9 0.0 8.7e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 KXS93605.1 - 0.0021 17.3 0.0 0.0038 16.4 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein DXP_reductoisom PF02670.16 KXS93605.1 - 0.0092 16.7 0.0 0.028 15.1 0.0 1.8 2 0 0 2 2 2 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DapB_N PF01113.20 KXS93605.1 - 0.021 15.0 0.0 0.033 14.3 0.0 1.4 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.19 KXS93605.1 - 0.021 13.8 0.0 0.17 10.9 0.0 1.9 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family GFO_IDH_MocA PF01408.22 KXS93605.1 - 0.067 14.0 0.1 0.2 12.5 0.1 1.7 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold adh_short_C2 PF13561.6 KXS93608.1 - 2.1e-49 168.2 0.5 5.2e-47 160.4 0.5 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS93608.1 - 1e-43 149.1 0.6 1.3e-43 148.7 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS93608.1 - 2.3e-15 57.0 0.1 3.2e-15 56.5 0.1 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KXS93608.1 - 0.0094 15.9 0.2 0.016 15.1 0.2 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 KXS93608.1 - 0.037 14.1 0.2 0.057 13.5 0.2 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Tom6 PF17112.5 KXS93609.1 - 0.00054 19.4 0.1 0.001 18.5 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom6, fungal ADH_N PF08240.12 KXS93610.1 - 1.1e-05 25.2 0.0 2.6e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain GFO_IDH_MocA PF01408.22 KXS93611.1 - 1.6e-08 35.4 0.0 6.6e-08 33.4 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KXS93611.1 - 0.017 15.1 0.0 0.037 14.0 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain IL17 PF06083.11 KXS93612.1 - 0.15 12.5 0.0 0.39 11.2 0.0 1.7 1 0 0 1 1 1 0 Interleukin-17 Pyrid_oxidase_2 PF13883.6 KXS93613.1 - 5.9e-36 124.0 0.0 7.7e-36 123.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase KRTAP PF11759.8 KXS93614.1 - 1.1 9.9 21.6 2.6 8.6 21.6 1.6 1 0 0 1 1 1 0 Keratin-associated matrix Med8 PF10232.9 KXS93615.1 - 6.1e-34 117.6 1.2 7.3e-34 117.4 1.2 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 Ribosomal_S30 PF04758.14 KXS93616.1 - 1.4e-29 102.1 8.5 1.5e-29 102.0 8.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 DNA_methylase PF00145.17 KXS93617.1 - 3.1e-31 109.0 0.0 3.1e-19 69.5 0.0 2.3 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase TPR_14 PF13428.6 KXS93618.1 - 5.3e-25 86.0 25.7 0.0026 18.4 0.2 12.2 6 3 8 14 14 14 8 Tetratricopeptide repeat HAT PF02184.16 KXS93618.1 - 1.7e-20 72.6 71.1 1.7e-14 53.5 3.6 14.0 15 0 0 15 15 15 4 HAT (Half-A-TPR) repeat TPR_19 PF14559.6 KXS93618.1 - 1.6e-18 67.0 0.1 0.00028 21.3 0.0 7.4 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 KXS93618.1 - 6.1e-14 51.3 2.3 0.0018 18.5 0.0 6.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXS93618.1 - 1.5e-10 40.4 17.2 0.0094 16.0 0.1 9.1 10 0 0 10 10 9 2 Tetratricopeptide repeat Suf PF05843.14 KXS93618.1 - 1.5e-10 41.5 25.6 0.0045 17.0 0.3 6.9 3 3 2 6 6 6 4 Suppressor of forked protein (Suf) TPR_15 PF13429.6 KXS93618.1 - 6.7e-09 35.4 14.1 0.24 10.6 0.3 5.7 2 1 4 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 KXS93618.1 - 2.5e-08 34.4 7.0 0.15 12.7 0.0 6.2 6 1 0 6 6 6 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KXS93618.1 - 3.9e-07 30.0 5.3 0.14 12.2 0.0 5.9 6 0 0 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.6 KXS93618.1 - 0.00016 21.6 9.7 18 5.8 0.0 7.6 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXS93618.1 - 0.00021 21.7 17.4 32 5.4 0.2 8.6 9 0 0 9 9 8 0 Tetratricopeptide repeat NRDE-2 PF08424.10 KXS93618.1 - 0.023 13.8 24.7 0.2 10.7 2.2 5.3 3 2 2 5 5 5 0 NRDE-2, necessary for RNA interference U3_assoc_6 PF08640.11 KXS93618.1 - 0.029 14.4 21.7 0.43 10.7 1.1 7.5 5 2 2 8 8 8 0 U3 small nucleolar RNA-associated protein 6 IMS_C PF11799.8 KXS93618.1 - 0.12 13.0 0.0 6.8 7.4 0.0 2.7 2 0 0 2 2 2 0 impB/mucB/samB family C-terminal domain TPR_1 PF00515.28 KXS93618.1 - 0.99 9.3 12.2 12 5.9 0.0 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat c-SKI_SMAD_bind PF08782.10 KXS93618.1 - 1.6 9.0 4.9 3.9 7.8 0.1 3.8 3 1 0 3 3 3 0 c-SKI Smad4 binding domain TPR_12 PF13424.6 KXS93618.1 - 2.3 8.6 21.1 19 5.6 0.1 8.3 10 0 0 10 10 10 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 KXS93618.1 - 4.6 7.3 26.7 1 9.3 2.4 6.9 5 3 4 9 9 9 0 Mad3/BUB1 homology region 1 Nop PF01798.18 KXS93619.1 - 6.9e-73 244.9 0.0 1.3e-72 244.1 0.0 1.4 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 KXS93619.1 - 4.2e-47 160.0 0.8 4.2e-47 160.0 0.8 2.2 2 0 0 2 2 2 1 Prp31 C terminal domain RRN3 PF05327.11 KXS93619.1 - 0.16 10.4 6.1 0.26 9.8 6.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Glyco_hydro_76 PF03663.14 KXS93620.1 - 1.3e-163 544.8 22.1 1.5e-163 544.6 22.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KXS93620.1 - 0.96 8.5 14.9 5.2 6.0 6.4 2.9 1 1 1 2 2 2 0 Glycosyl Hydrolase Family 88 AMP-binding PF00501.28 KXS93621.1 - 5e-23 81.4 1.0 5.3e-23 81.3 1.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Glyco_hydro_65C PF03633.15 KXS93621.1 - 0.089 12.7 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, C-terminal domain OB_NTP_bind PF07717.16 KXS93622.1 - 1.6e-21 76.4 0.0 3.5e-21 75.3 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KXS93622.1 - 2.5e-21 76.0 0.1 2.5e-21 76.0 0.1 2.4 3 0 0 3 3 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KXS93622.1 - 3.6e-14 53.1 0.0 1.2e-13 51.3 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 KXS93622.1 - 1.6e-11 44.4 1.5 1.6e-11 44.4 1.5 1.9 2 0 0 2 2 2 1 S1 RNA binding domain DEAD PF00270.29 KXS93622.1 - 0.00013 21.8 0.5 0.0004 20.2 0.5 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KXS93622.1 - 0.0004 20.7 0.1 0.0014 18.9 0.1 1.9 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KXS93622.1 - 0.00061 18.9 0.0 0.0029 16.7 0.0 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.6 KXS93622.1 - 0.0065 16.2 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KXS93622.1 - 0.04 13.9 0.3 0.83 9.7 0.3 2.6 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KXS93622.1 - 0.047 12.9 0.0 0.087 12.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 KXS93622.1 - 0.056 12.9 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_19 PF13245.6 KXS93622.1 - 0.074 13.4 0.1 0.19 12.1 0.1 1.6 1 0 0 1 1 1 0 AAA domain Microtub_bd PF16796.5 KXS93622.1 - 0.12 12.3 0.2 6.2 6.7 0.0 3.0 3 0 0 3 3 3 0 Microtubule binding AAA_33 PF13671.6 KXS93622.1 - 0.53 10.4 0.0 0.53 10.4 0.0 2.5 3 0 0 3 3 2 0 AAA domain Ras PF00071.22 KXS93623.1 - 2.2e-53 180.2 0.1 2.8e-53 179.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXS93623.1 - 1.2e-31 109.4 0.1 2e-31 108.7 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXS93623.1 - 2.8e-12 46.5 0.2 3.2e-12 46.2 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KXS93623.1 - 9.4e-06 25.3 0.1 1.8e-05 24.4 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KXS93623.1 - 0.00023 20.6 0.0 0.00028 20.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KXS93623.1 - 0.0061 16.6 0.0 0.0091 16.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KXS93623.1 - 0.012 14.9 0.1 0.014 14.7 0.1 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region TIR_2 PF13676.6 KXS93623.1 - 0.019 15.6 0.0 0.028 15.0 0.0 1.2 1 0 0 1 1 1 0 TIR domain FlgH PF02107.16 KXS93623.1 - 0.052 13.2 0.2 0.076 12.6 0.2 1.2 1 0 0 1 1 1 0 Flagellar L-ring protein TetR_C_16 PF17920.1 KXS93623.1 - 0.11 12.7 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain FeoB_N PF02421.18 KXS93623.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B Nop53 PF07767.11 KXS93624.1 - 2.3e-99 333.5 40.4 3e-99 333.1 40.4 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) GREB1 PF15782.5 KXS93624.1 - 5.8 3.9 9.1 8.6 3.3 9.1 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Abhydrolase_6 PF12697.7 KXS93625.1 - 7.2e-09 36.6 0.1 1.4e-08 35.7 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXS93625.1 - 7.7e-08 31.9 0.0 1.4e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXS93625.1 - 5.8e-05 22.9 0.1 0.0001 22.1 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXS93625.1 - 0.0022 17.5 0.0 0.022 14.2 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KXS93625.1 - 0.0092 15.9 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Stk19 PF10494.9 KXS93626.1 - 4e-73 246.1 0.0 1.4e-72 244.3 0.0 1.8 2 1 0 2 2 2 1 Serine-threonine protein kinase 19 Peptidase_M18 PF02127.15 KXS93627.1 - 7.1e-158 525.9 0.0 1.9e-157 524.5 0.0 1.6 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) DAGAT PF03982.13 KXS93628.1 - 3.3e-88 295.5 0.0 4.3e-88 295.1 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase APH PF01636.23 KXS93630.1 - 1.6e-19 70.8 0.2 2.9e-19 69.9 0.2 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXS93630.1 - 1.5e-06 28.0 0.0 2.7e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 KXS93630.1 - 0.028 13.7 0.0 0.22 10.7 0.0 2.0 1 1 0 1 1 1 0 Fructosamine kinase Pkinase PF00069.25 KXS93630.1 - 0.074 12.4 0.0 3.5 6.9 0.0 2.2 2 0 0 2 2 2 0 Protein kinase domain RIO1 PF01163.22 KXS93630.1 - 0.088 12.4 0.0 3.7 7.1 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Seadorna_VP7 PF07387.11 KXS93630.1 - 0.13 11.2 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Get5_bdg PF16843.5 KXS93630.1 - 0.15 11.6 0.1 9.5 5.8 0.0 2.3 2 0 0 2 2 2 0 Binding domain to Get4 on Get5, Golgi to ER traffic protein muHD PF10291.9 KXS93631.1 - 3.9e-70 236.3 0.0 6e-70 235.7 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 KXS93631.1 - 4e-10 39.8 0.0 1.7e-09 37.8 0.0 2.1 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain PapD_N PF00345.20 KXS93631.1 - 0.061 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain muHD PF10291.9 KXS93632.1 - 3.2e-70 236.6 0.0 5e-70 235.9 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain PapD_N PF00345.20 KXS93632.1 - 0.053 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain FCH PF00611.23 KXS93633.1 - 7.9e-08 32.5 0.0 1e-07 32.2 0.0 1.2 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain KxDL PF10241.9 KXS93634.1 - 6.3e-30 103.3 1.8 8.3e-30 102.9 1.8 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein Atg14 PF10186.9 KXS93634.1 - 0.055 12.6 1.0 0.082 12.0 1.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 XylR_N PF06505.11 KXS93634.1 - 0.15 11.8 0.4 0.24 11.2 0.4 1.2 1 0 0 1 1 1 0 Activator of aromatic catabolism DUF4407 PF14362.6 KXS93634.1 - 0.22 10.8 3.7 0.28 10.5 3.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HSP20 PF00011.21 KXS93635.1 - 3.1e-22 78.6 0.4 1.4e-14 54.1 0.0 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KXS93635.1 - 6.4e-06 25.6 0.1 9.1e-05 21.9 0.1 2.2 1 1 0 1 1 1 1 HSP20-like domain found in ArsA DUF3672 PF12421.8 KXS93636.1 - 0.023 14.6 0.3 0.051 13.5 0.2 1.6 2 0 0 2 2 2 0 Fibronectin type III protein Glutaminase PF04960.15 KXS93639.1 - 9.8e-113 376.1 0.0 1.2e-112 375.8 0.0 1.1 1 0 0 1 1 1 1 Glutaminase F-box-like PF12937.7 KXS93640.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 F-box-like Hamartin PF04388.12 KXS93641.1 - 9.3e-25 87.4 5.3 9.3e-25 87.4 5.3 3.9 3 1 0 3 3 3 2 Hamartin protein YabA PF06156.13 KXS93641.1 - 0.32 11.6 0.1 0.32 11.6 0.1 4.7 2 1 2 4 4 4 0 Initiation control protein YabA Fungal_trans_2 PF11951.8 KXS93645.1 - 1.4e-10 40.6 0.3 2e-10 40.1 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS93645.1 - 2.3e-06 27.6 10.3 4e-06 26.8 10.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Coatomer_WDAD PF04053.14 KXS93646.1 - 3.5e-163 543.8 0.0 8.8e-163 542.5 0.0 1.6 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 KXS93646.1 - 6.6e-38 128.0 8.6 1e-05 26.2 0.0 8.4 7 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS93646.1 - 3.1e-08 33.8 0.0 2.9 8.3 0.0 6.3 4 2 3 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXS93646.1 - 9e-05 21.3 2.8 0.14 10.8 0.0 4.1 1 1 2 4 4 4 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 KXS93646.1 - 0.059 13.4 0.0 9.5 6.3 0.0 3.4 2 2 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region eIF2A PF08662.11 KXS93646.1 - 0.073 12.9 0.0 22 4.8 0.0 3.6 3 1 1 4 4 4 0 Eukaryotic translation initiation factor eIF2A SusF_SusE PF16411.5 KXS93646.1 - 0.1 13.1 0.1 0.66 10.5 0.0 2.4 3 0 0 3 3 3 0 Outer membrane protein SusF_SusE Pox_Rif PF03340.13 KXS93646.1 - 0.12 10.7 0.0 0.32 9.4 0.0 1.5 2 0 0 2 2 2 0 Poxvirus rifampicin resistance protein eIF3g PF12353.8 KXS93647.1 - 9e-41 139.2 1.8 1.3e-40 138.7 1.8 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 KXS93647.1 - 4.2e-18 64.9 0.0 7.2e-18 64.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXS93647.1 - 0.041 13.7 0.0 0.083 12.8 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_5 PF13893.6 KXS93647.1 - 0.13 11.9 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Acetyltransf_3 PF13302.7 KXS93648.1 - 4.3e-29 102.0 0.0 5.4e-29 101.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KXS93648.1 - 1.4e-06 28.1 0.0 0.44 10.2 0.1 3.1 3 0 0 3 3 3 3 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXS93648.1 - 7.2e-06 26.2 0.0 0.0023 18.2 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 KXS93648.1 - 0.11 12.7 0.0 8.3 6.5 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Amidohydro_3 PF07969.11 KXS93650.1 - 1.2e-07 31.6 0.1 8.1e-06 25.6 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 KXS93650.1 - 1.2e-05 24.8 0.1 2.6e-05 23.7 0.1 1.7 1 1 0 1 1 1 1 Amidohydrolase family PIEZO PF15917.5 KXS93651.1 - 8 5.9 11.7 2.2 7.7 3.7 2.5 2 0 0 2 2 2 0 Piezo Vps39_1 PF10366.9 KXS93652.1 - 1.2e-28 99.5 0.0 1.3e-27 96.2 0.0 2.8 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 KXS93652.1 - 4e-26 91.6 0.0 1e-25 90.3 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 KXS93652.1 - 1.7e-17 63.9 0.0 8.8e-17 61.6 0.0 1.9 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.20 KXS93652.1 - 0.00053 19.9 1.5 0.00053 19.9 1.5 2.7 3 0 0 3 3 3 1 Region in Clathrin and VPS TPR_1 PF00515.28 KXS93652.1 - 0.0016 18.2 6.6 2.2 8.2 1.4 4.2 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXS93652.1 - 0.022 15.0 6.4 6.3 7.2 0.2 4.6 4 2 1 5 5 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXS93652.1 - 0.053 13.7 6.3 12 6.3 1.2 4.3 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXS93652.1 - 0.075 12.9 1.4 33 4.5 0.0 4.2 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXS93652.1 - 0.93 9.9 5.9 0.47 10.8 0.4 3.3 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KXS93652.1 - 1.1 10.0 2.9 15 6.3 0.3 3.3 3 1 0 3 3 2 0 Tetratricopeptide repeat TPR_3 PF07720.12 KXS93652.1 - 1.3 9.0 7.0 3 7.9 0.2 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat LSM PF01423.22 KXS93653.1 - 5.4e-15 54.8 0.6 8.2e-15 54.2 0.6 1.3 1 0 0 1 1 1 1 LSM domain adh_short PF00106.25 KXS93654.1 - 3.8e-12 46.1 0.0 4.3e-12 45.9 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS93654.1 - 5.8e-10 39.1 0.0 6.9e-10 38.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase tRNA-synt_2c PF01411.19 KXS93655.1 - 2.6e-07 29.5 0.1 3.3e-07 29.2 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KXS93655.1 - 0.00088 19.3 0.1 0.0019 18.2 0.1 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain FAD_binding_3 PF01494.19 KXS93656.1 - 1.3e-17 64.1 0.0 2.6e-17 63.1 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXS93656.1 - 1.9e-05 24.4 5.4 0.0053 16.4 1.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXS93656.1 - 2e-05 24.0 2.0 0.0023 17.2 0.4 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXS93656.1 - 2.1e-05 24.7 0.0 9e-05 22.6 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KXS93656.1 - 6.2e-05 22.0 1.9 0.37 9.6 0.6 3.0 3 0 0 3 3 3 2 Tryptophan halogenase Lycopene_cycl PF05834.12 KXS93656.1 - 0.0011 18.1 0.3 0.079 12.0 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KXS93656.1 - 0.0022 17.3 0.2 0.0034 16.7 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXS93656.1 - 0.0028 17.7 1.9 0.078 13.0 0.2 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Rossmann-like PF10727.9 KXS93656.1 - 0.011 15.5 0.1 0.022 14.6 0.1 1.4 1 0 0 1 1 1 0 Rossmann-like domain FAD_binding_2 PF00890.24 KXS93656.1 - 0.02 14.0 0.3 0.032 13.3 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 KXS93656.1 - 0.023 13.9 0.2 0.023 13.9 0.2 1.6 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 KXS93656.1 - 0.039 14.5 0.4 0.29 11.7 0.2 2.6 4 0 0 4 4 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXS93656.1 - 0.058 12.1 0.6 0.12 11.0 0.5 1.5 2 0 0 2 2 2 0 HI0933-like protein Amino_oxidase PF01593.24 KXS93656.1 - 0.094 12.0 0.1 0.094 12.0 0.1 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase PS-DH PF14765.6 KXS93657.1 - 6e-07 29.0 0.0 0.00027 20.3 0.0 2.9 1 1 0 1 1 1 1 Polyketide synthase dehydratase MFS_1 PF07690.16 KXS93658.1 - 1.8e-07 30.4 28.4 1.8e-07 30.4 28.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 KXS93658.1 - 0.0014 18.4 1.0 0.0014 18.4 1.0 2.0 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.24 KXS93658.1 - 0.1 11.4 13.1 0.074 11.9 10.6 2.0 1 1 1 2 2 2 0 Sugar (and other) transporter Syntaxin-6_N PF09177.11 KXS93665.1 - 0.056 14.0 0.1 6.9 7.3 0.0 2.2 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF3540 PF12059.8 KXS93665.1 - 0.076 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3540) zf_C2H2_13 PF18508.1 KXS93665.1 - 0.12 12.0 0.1 0.3 10.7 0.0 1.7 2 0 0 2 2 2 0 Zinc finger domain CAP PF00188.26 KXS93666.1 - 6.6e-18 65.8 2.1 6.6e-18 65.8 2.1 1.9 2 0 0 2 2 2 1 Cysteine-rich secretory protein family p450 PF00067.22 KXS93667.1 - 3.7e-50 171.0 0.0 1.4e-49 169.1 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.24 KXS93668.1 - 3e-21 75.8 8.6 3.6e-21 75.6 8.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS93668.1 - 1.6e-09 37.2 6.7 1.9e-09 36.9 6.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 KXS93668.1 - 0.00066 18.3 6.6 0.00098 17.8 6.2 1.5 1 1 1 2 2 2 1 MFS/sugar transport protein PUCC PF03209.15 KXS93668.1 - 0.1 11.6 2.7 0.14 11.1 2.7 1.1 1 0 0 1 1 1 0 PUCC protein Phage_holin_3_2 PF04550.12 KXS93668.1 - 0.12 12.9 0.7 0.31 11.6 0.7 1.7 1 0 0 1 1 1 0 Phage holin family 2 FAD_binding_3 PF01494.19 KXS93669.1 - 9.7e-29 100.7 0.0 1.3e-28 100.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXS93669.1 - 7.6e-13 48.8 1.6 4.4e-06 26.5 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXS93669.1 - 1.1e-09 38.0 0.3 0.00035 19.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KXS93669.1 - 4.4e-07 29.6 1.9 0.00032 20.1 0.1 3.2 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase HI0933_like PF03486.14 KXS93669.1 - 5.3e-07 28.7 1.2 2.1e-06 26.7 1.2 1.8 1 1 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 KXS93669.1 - 1.6e-05 25.0 0.3 3.9e-05 23.8 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXS93669.1 - 0.00011 22.7 1.3 0.47 11.0 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXS93669.1 - 0.00018 20.5 1.9 0.16 10.7 0.3 2.2 1 1 1 2 2 2 2 Tryptophan halogenase Lycopene_cycl PF05834.12 KXS93669.1 - 0.00026 20.1 1.1 0.0013 17.9 1.1 1.9 1 1 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KXS93669.1 - 0.0011 18.1 3.2 0.0018 17.4 3.2 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KXS93669.1 - 0.0027 17.1 0.1 0.0042 16.5 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 KXS93669.1 - 0.0041 17.0 0.2 0.0069 16.3 0.2 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 KXS93669.1 - 0.0054 16.0 0.0 0.33 10.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXS93669.1 - 0.0075 15.5 0.1 0.012 14.9 0.1 1.2 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 KXS93669.1 - 0.0093 15.1 0.2 0.014 14.5 0.2 1.4 1 1 0 1 1 1 1 Glucose inhibited division protein A SE PF08491.10 KXS93669.1 - 0.019 14.0 0.0 0.33 9.9 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase MFS_1 PF07690.16 KXS93670.1 - 4.9e-20 71.7 40.9 6.6e-20 71.3 38.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS93670.1 - 8.4e-10 38.1 10.3 8.4e-10 38.1 10.3 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter TauD PF02668.16 KXS93680.1 - 1.4e-14 54.5 0.0 1.4e-11 44.7 0.0 2.1 2 0 0 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family AA_permease PF00324.21 KXS93681.1 - 4.9e-90 302.4 44.8 4e-56 190.6 23.3 3.0 1 1 2 3 3 3 3 Amino acid permease AA_permease_2 PF13520.6 KXS93681.1 - 2.6e-09 36.5 45.3 2e-06 26.9 24.2 2.2 1 1 1 2 2 2 2 Amino acid permease Pet100 PF09803.9 KXS93681.1 - 0.078 13.5 0.1 0.17 12.5 0.1 1.5 1 0 0 1 1 1 0 Pet100 RhoGAP PF00620.27 KXS93682.1 - 2.3e-38 131.4 0.1 4.8e-38 130.4 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 KXS93682.1 - 2.2e-28 98.2 35.8 4.2e-12 46.1 5.1 5.0 5 0 0 5 5 5 4 LIM domain PAP2 PF01569.21 KXS93682.1 - 0.16 11.7 0.0 3.9 7.2 0.0 2.4 2 0 0 2 2 2 0 PAP2 superfamily RNA_pol_Rpb4 PF03874.16 KXS93683.1 - 1.1e-17 64.5 0.4 1.4e-17 64.2 0.4 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 GPI-anchored PF10342.9 KXS93684.1 - 1.6e-13 51.2 0.4 1.6e-13 51.2 0.4 2.6 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Ferric_reduct PF01794.19 KXS93685.1 - 1e-22 80.6 12.0 1e-22 80.6 12.0 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KXS93685.1 - 6.2e-10 39.4 0.0 1.5e-08 34.9 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KXS93685.1 - 2.7e-06 27.4 0.0 0.067 13.3 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.21 KXS93685.1 - 0.031 14.9 0.0 0.089 13.4 0.0 1.8 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain DUF2784 PF10861.8 KXS93686.1 - 0.48 10.5 3.1 1.8 8.6 1.0 2.4 1 1 0 1 1 1 0 Protein of Unknown function (DUF2784) SSF PF00474.17 KXS93687.1 - 2.6e-06 26.6 12.6 2.6e-06 26.6 12.6 3.3 3 1 0 3 3 3 1 Sodium:solute symporter family PspC PF04024.12 KXS93687.1 - 0.19 11.6 2.3 1.9 8.4 2.3 2.7 1 0 0 1 1 1 0 PspC domain Tmemb_55A PF09788.9 KXS93687.1 - 6.3 5.8 4.8 1.8 7.5 0.4 2.1 2 0 0 2 2 2 0 Transmembrane protein 55A SSF PF00474.17 KXS93689.1 - 1.8e-09 37.0 12.1 1.8e-09 37.0 12.1 3.3 3 1 0 3 3 3 1 Sodium:solute symporter family Tmemb_55A PF09788.9 KXS93689.1 - 7.4 5.6 4.8 2.1 7.3 0.4 2.1 2 0 0 2 2 2 0 Transmembrane protein 55A SSF PF00474.17 KXS93690.1 - 1.4e-06 27.4 11.9 1.4e-06 27.4 11.9 3.3 3 1 0 3 3 3 1 Sodium:solute symporter family PspC PF04024.12 KXS93690.1 - 0.19 11.6 2.2 1.9 8.3 2.2 2.8 1 0 0 1 1 1 0 PspC domain Tmemb_55A PF09788.9 KXS93690.1 - 7.1 5.6 4.8 2 7.5 0.4 2.0 2 0 0 2 2 2 0 Transmembrane protein 55A VWA_2 PF13519.6 KXS93691.1 - 1.6e-05 25.5 0.0 6.8e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 KXS93691.1 - 3.6e-05 24.1 0.0 0.00022 21.5 0.0 2.3 2 1 0 2 2 2 1 von Willebrand factor type A domain Glyco_hydro_61 PF03443.14 KXS93693.1 - 3.8e-43 147.8 0.0 5e-43 147.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 RRM_1 PF00076.22 KXS93694.1 - 4.7e-09 35.9 0.0 1.1e-08 34.8 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXS93694.1 - 1.4e-05 24.7 0.0 2e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KXS93694.1 - 0.023 14.8 0.0 0.053 13.6 0.0 1.6 1 1 0 1 1 1 0 Limkain b1 Autophagy_act_C PF03987.15 KXS93695.1 - 3.9e-14 53.0 0.5 9.8e-14 51.7 0.0 2.0 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain WD40 PF00400.32 KXS93696.1 - 3.7e-16 59.2 10.6 0.00025 21.8 0.1 6.4 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS93696.1 - 1.3e-07 31.8 0.0 0.0062 16.8 0.0 4.1 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KXS93696.1 - 0.013 15.4 0.1 12 6.0 0.0 3.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Gmad1 PF10647.9 KXS93696.1 - 0.035 13.9 0.1 1.3 8.7 0.0 2.9 3 0 0 3 3 3 0 Lipoprotein LpqB beta-propeller domain Glyco_hydro_62 PF03664.13 KXS93697.1 - 5.7e-141 468.6 12.1 6.6e-141 468.4 12.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 Adap_comp_sub PF00928.21 KXS93698.1 - 1.6e-92 309.6 0.0 3.5e-92 308.5 0.0 1.5 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KXS93698.1 - 1.4e-09 38.0 0.3 2.3e-09 37.3 0.3 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Ribosomal_L27 PF01016.19 KXS93700.1 - 1.2e-28 98.9 0.4 2.3e-28 98.0 0.4 1.5 1 0 0 1 1 1 1 Ribosomal L27 protein ECR1_N PF14382.6 KXS93700.1 - 0.0033 17.2 0.2 0.0094 15.7 0.1 1.8 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region DPCD PF14913.6 KXS93702.1 - 0.0019 17.6 0.1 0.0025 17.2 0.1 1.2 1 0 0 1 1 1 1 DPCD protein family Vps52 PF04129.12 KXS93703.1 - 0.0041 15.9 0.1 0.0045 15.8 0.1 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Rtt106 PF08512.12 KXS93704.1 - 5e-31 107.0 0.0 9.9e-31 106.0 0.0 1.5 1 0 0 1 1 1 1 Histone chaperone Rttp106-like PH_18 PF18469.1 KXS93704.1 - 1.3e-08 35.0 0.1 1.4e-07 31.6 0.1 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain SusE PF14292.6 KXS93704.1 - 0.049 13.9 0.4 13 6.0 0.0 3.0 3 0 0 3 3 3 0 SusE outer membrane protein Sugarporin_N PF11471.8 KXS93704.1 - 0.8 9.7 3.2 1.8 8.6 3.2 1.6 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Glyco_hydro_47 PF01532.20 KXS93705.1 - 3e-51 174.8 0.0 3.3e-51 174.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Alpha-amylase PF00128.24 KXS93708.1 - 7.8e-18 65.1 1.5 2.5e-17 63.4 1.5 1.8 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 KXS93708.1 - 4e-14 52.9 0.1 6.9e-14 52.1 0.1 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KXS93708.1 - 4.6e-06 26.3 0.0 9.9e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 EI24 PF07264.11 KXS93709.1 - 1.1e-15 58.4 2.0 1.8e-15 57.6 2.0 1.4 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) TPPII_N PF12583.8 KXS93709.1 - 2.6 8.6 10.4 4.5 7.9 10.4 1.3 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal Glycos_transf_2 PF00535.26 KXS93710.1 - 2e-24 86.3 0.0 3.7e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 KXS93710.1 - 4e-19 69.3 0.4 4e-19 69.3 0.4 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KXS93710.1 - 2.6e-18 66.8 0.0 3.7e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KXS93710.1 - 1.5e-16 60.4 0.0 2.4e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Cellulose_synt PF03552.14 KXS93710.1 - 0.00044 18.9 5.2 0.028 12.9 1.8 2.1 2 0 0 2 2 2 2 Cellulose synthase Glyco_tranf_2_2 PF10111.9 KXS93710.1 - 0.17 11.4 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 OmpH PF03938.14 KXS93710.1 - 0.39 11.1 2.6 2.6 8.4 0.0 2.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) RicinB_lectin_2 PF14200.6 KXS93711.1 - 0.0014 19.3 1.0 0.79 10.5 0.0 3.0 2 1 0 3 3 3 2 Ricin-type beta-trefoil lectin domain-like BASP1 PF05466.12 KXS93711.1 - 5.3 7.0 14.7 9 6.2 14.7 1.3 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) QWRF PF04484.12 KXS93711.1 - 7.1 6.3 9.6 10 5.8 9.6 1.1 1 0 0 1 1 1 0 QWRF family UDPG_MGDP_dh_N PF03721.14 KXS93713.1 - 9.9e-50 168.7 0.0 2.4e-49 167.5 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 KXS93713.1 - 1.5e-31 108.4 0.0 3.6e-31 107.2 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 KXS93713.1 - 2.8e-23 82.3 0.0 1e-19 70.9 0.0 3.2 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Sacchrp_dh_NADP PF03435.18 KXS93713.1 - 0.001 19.3 0.0 0.0031 17.8 0.0 1.8 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 KXS93713.1 - 0.062 13.6 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_2 PF07992.14 KXS93713.1 - 0.089 12.0 0.0 0.35 10.1 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 KXS93715.1 - 9.9e-50 168.7 0.0 2.4e-49 167.5 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 KXS93715.1 - 1.5e-31 108.4 0.0 3.6e-31 107.2 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 KXS93715.1 - 2.8e-23 82.3 0.0 1e-19 70.9 0.0 3.2 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Sacchrp_dh_NADP PF03435.18 KXS93715.1 - 0.001 19.3 0.0 0.0031 17.8 0.0 1.8 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 KXS93715.1 - 0.062 13.6 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_2 PF07992.14 KXS93715.1 - 0.089 12.0 0.0 0.35 10.1 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 KXS93723.1 - 6.6e-115 382.6 0.0 2.7e-75 252.9 0.0 2.3 2 1 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 KXS93723.1 - 2.2e-95 319.4 8.4 1.6e-94 316.5 5.7 2.3 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 KXS93723.1 - 1.8e-31 108.7 0.1 3.7e-31 107.7 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 KXS93723.1 - 3.7e-28 97.5 0.0 7.6e-28 96.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 KXS93723.1 - 5.1e-26 90.7 0.1 1.7e-25 89.0 0.1 2.0 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle NAD_binding_7 PF13241.6 KXS93723.1 - 0.04 14.4 0.0 3.4 8.1 0.0 3.4 2 1 1 3 3 3 0 Putative NAD(P)-binding Tap-RNA_bind PF09162.10 KXS93723.1 - 0.072 12.9 0.2 0.26 11.1 0.1 2.0 2 0 0 2 2 2 0 Tap, RNA-binding Zn_clus PF00172.18 KXS93724.1 - 1.7e-17 63.2 37.1 5.2e-10 39.3 11.0 3.2 3 0 0 3 3 3 2 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 KXS93724.1 - 5e-07 29.8 15.3 0.00017 21.8 1.7 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS93724.1 - 0.067 14.1 1.1 0.067 14.1 1.1 4.4 5 0 0 5 5 5 0 C2H2-type zinc finger PAT1 PF09770.9 KXS93724.1 - 0.22 9.7 0.4 0.24 9.6 0.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf_C2H2_ZHX PF18387.1 KXS93724.1 - 0.43 10.3 5.0 1.1 8.9 0.2 3.1 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-H2C2_2 PF13465.6 KXS93724.1 - 0.75 10.3 17.7 4 8.0 0.2 5.4 5 0 0 5 5 5 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KXS93724.1 - 3.5 8.0 0.0 3.5 8.0 0.0 3.9 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding Fungal_trans_2 PF11951.8 KXS93725.1 - 9.2e-10 37.9 3.4 9.2e-10 37.9 3.4 2.4 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS93725.1 - 1.9e-06 27.9 12.2 3.6e-06 27.0 12.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 5_nucleotid PF05761.14 KXS93725.1 - 0.14 11.1 2.0 0.29 10.0 2.0 1.4 1 0 0 1 1 1 0 5' nucleotidase family RPA43_OB PF17875.1 KXS93725.1 - 5.4 7.7 7.4 15 6.2 4.1 2.5 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I Rrn6 PF10214.9 KXS93725.1 - 5.4 5.4 13.8 9.3 4.6 13.8 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor MFS_1 PF07690.16 KXS93726.1 - 4.9e-34 117.8 23.2 4.9e-34 117.8 23.2 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily PBP1_TM PF14812.6 KXS93726.1 - 0.18 12.2 4.0 0.46 10.9 4.0 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GCIP PF13324.6 KXS93726.1 - 0.21 11.2 1.1 0.32 10.6 1.1 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Cwf_Cwc_15 PF04889.12 KXS93726.1 - 0.85 9.3 8.6 1.3 8.7 8.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF4611 PF15387.6 KXS93726.1 - 0.93 9.7 4.9 1.9 8.7 4.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) CENP-B_dimeris PF09026.10 KXS93726.1 - 2.2 8.7 12.0 3.5 8.1 11.3 1.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF2457 PF10446.9 KXS93726.1 - 4.2 6.4 9.5 6.1 5.9 9.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Syja_N PF02383.18 KXS93727.1 - 1.1e-77 261.5 0.1 3.1e-77 260.0 0.0 1.7 2 0 0 2 2 2 1 SacI homology domain Sugar_tr PF00083.24 KXS93735.1 - 1.6e-38 132.7 9.4 2.2e-38 132.3 9.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Sugar_tr PF00083.24 KXS93736.1 - 2.6e-55 188.1 20.9 3.4e-55 187.7 20.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS93736.1 - 1.1e-16 60.8 13.4 1.1e-16 60.8 13.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KXS93736.1 - 0.076 11.9 11.3 0.74 8.6 2.2 2.9 1 1 2 3 3 3 0 MFS_1 like family TraL PF07178.11 KXS93736.1 - 3.4 8.2 11.1 0.89 10.1 0.2 3.5 3 1 0 3 3 3 0 TraL protein Sugar_tr PF00083.24 KXS93737.1 - 2.4e-44 151.9 14.6 3.2e-44 151.6 14.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS93737.1 - 2.8e-08 33.1 4.8 2.8e-08 33.1 4.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TraL PF07178.11 KXS93737.1 - 1.2 9.6 8.7 1 9.9 0.3 3.1 3 0 0 3 3 3 0 TraL protein ELH PF02323.15 KXS93738.1 - 2.9 7.2 6.2 0.85 8.9 2.1 1.8 1 1 1 2 2 2 0 Egg-laying hormone precursor Frag1 PF10277.9 KXS93739.1 - 4.2e-28 98.4 12.8 4.8e-28 98.2 12.8 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family 7TM_GPCR_Srh PF10318.9 KXS93739.1 - 0.0032 16.6 5.6 0.0045 16.1 5.6 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh DUF3087 PF11286.8 KXS93739.1 - 0.084 12.3 0.3 0.13 11.8 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) LapA_dom PF06305.11 KXS93739.1 - 0.091 12.6 0.1 11 5.9 0.0 2.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain MARVEL PF01284.23 KXS93739.1 - 0.64 10.0 10.0 1.7 8.7 9.5 2.0 1 1 0 1 1 1 0 Membrane-associating domain DUF2975 PF11188.8 KXS93739.1 - 7 6.5 9.9 0.42 10.5 3.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2975) p450 PF00067.22 KXS93740.1 - 3.8e-38 131.4 0.0 2.5e-37 128.7 0.0 1.9 2 0 0 2 2 2 1 Cytochrome P450 COX7B PF05392.11 KXS93740.1 - 0.21 11.3 0.7 8.8 6.1 0.0 3.1 3 0 0 3 3 3 0 Cytochrome C oxidase chain VIIB AA_permease PF00324.21 KXS93744.1 - 1.5e-127 426.1 38.9 1.9e-127 425.8 38.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXS93744.1 - 6e-43 147.3 43.4 7.1e-43 147.0 43.4 1.0 1 0 0 1 1 1 1 Amino acid permease DHquinase_I PF01487.15 KXS93747.1 - 9.1e-21 75.1 0.0 4e-20 73.0 0.0 2.0 2 0 0 2 2 2 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.11 KXS93747.1 - 7.6e-20 71.0 0.0 1.8e-19 69.8 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SKI PF01202.22 KXS93747.1 - 2e-12 47.5 0.0 3.6e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Shikimate kinase SDH_C PF18317.1 KXS93747.1 - 6.1e-12 45.1 0.1 1.1e-11 44.3 0.1 1.4 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 KXS93747.1 - 3.5e-06 27.1 0.0 8.5e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KXS93747.1 - 0.011 16.2 0.0 0.036 14.6 0.0 1.9 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AAA_8 PF12780.7 KXS93747.1 - 0.065 12.5 0.0 3.5 6.9 0.0 2.6 3 0 0 3 3 3 0 P-loop containing dynein motor region D4 DUF1100 PF06500.11 KXS93747.1 - 0.078 11.8 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) AAA_5 PF07728.14 KXS93747.1 - 0.14 12.1 0.0 0.49 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Rcd1 PF04078.13 KXS93747.1 - 0.24 10.7 0.0 0.42 9.9 0.0 1.3 1 0 0 1 1 1 0 Cell differentiation family, Rcd1-like Arylsulfotran_2 PF14269.6 KXS93748.1 - 1.1e-57 195.7 1.6 1.9e-57 194.9 1.4 1.5 2 0 0 2 2 2 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KXS93748.1 - 2e-25 89.5 0.1 4.8e-25 88.3 0.1 1.6 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) BNR_6 PF15899.5 KXS93748.1 - 0.083 13.0 1.1 0.49 10.6 0.0 2.8 2 0 0 2 2 2 0 BNR-Asp box repeat CTD_bind PF04818.13 KXS93753.1 - 6.6e-05 23.7 0.2 0.00022 22.0 0.2 2.0 2 0 0 2 2 2 1 RNA polymerase II-binding domain. Yop-YscD_ppl PF16693.5 KXS93753.1 - 0.09 12.2 0.1 0.25 10.7 0.1 1.6 1 1 1 2 2 2 0 Inner membrane component of T3SS, periplasmic domain Hid1 PF12722.7 KXS93754.1 - 4e-21 74.9 2.4 7e-21 74.1 2.4 1.4 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein NMD3 PF04981.13 KXS93754.1 - 0.14 11.6 0.1 0.2 11.1 0.1 1.2 1 0 0 1 1 1 0 NMD3 family Hid1 PF12722.7 KXS93755.1 - 1.8e-137 459.8 2.4 4.9e-137 458.3 2.4 1.6 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 KXS93755.1 - 1.4e-66 225.3 0.0 1.7e-66 225.0 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein WcbI PF18588.1 KXS93755.1 - 0.056 13.1 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Polysaccharide biosynthesis enzyme WcbI CvfB_WH PF17783.1 KXS93755.1 - 0.2 11.5 0.0 0.38 10.6 0.0 1.4 1 0 0 1 1 1 0 CvfB-like winged helix domain Hid1 PF12722.7 KXS93756.1 - 4.6e-168 560.9 0.0 1.1e-167 559.6 0.0 1.6 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 KXS93756.1 - 3.8e-72 243.7 0.0 4.5e-72 243.4 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein WcbI PF18588.1 KXS93756.1 - 0.092 12.3 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 Polysaccharide biosynthesis enzyme WcbI DUF1768 PF08719.11 KXS93757.1 - 6.7e-26 91.4 0.0 1.7e-25 90.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) UCH PF00443.29 KXS93758.1 - 8.5e-10 38.5 0.0 1.7e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CorA PF01544.18 KXS93758.1 - 0.039 13.3 0.2 0.071 12.4 0.2 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Nop14 PF04147.12 KXS93758.1 - 0.32 9.2 25.6 0.5 8.5 25.6 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 KXS93758.1 - 0.43 9.9 19.6 0.69 9.2 19.6 1.2 1 0 0 1 1 1 0 BUD22 LAP1C PF05609.12 KXS93758.1 - 0.5 9.4 8.0 1 8.4 8.0 1.4 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Cwf_Cwc_15 PF04889.12 KXS93758.1 - 2.7 7.7 27.7 1 9.0 24.2 2.0 1 1 1 2 2 2 0 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.12 KXS93758.1 - 4.2 6.7 30.9 7.1 6.0 30.9 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 KXS93758.1 - 8 4.6 18.3 13 4.0 18.3 1.2 1 0 0 1 1 1 0 CDC45-like protein p450 PF00067.22 KXS93762.1 - 7e-55 186.6 0.0 3.3e-54 184.4 0.0 2.0 3 0 0 3 3 3 1 Cytochrome P450 F1F0-ATPsyn_F PF10791.9 KXS93763.1 - 5.6e-20 71.6 1.8 1.4e-19 70.4 1.8 1.6 1 1 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi US30 PF17624.2 KXS93764.1 - 0.021 13.9 0.0 0.022 13.8 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function US30 PF17624.2 KXS93765.1 - 0.021 13.9 0.0 0.022 13.8 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function S-antigen PF05756.11 KXS93766.1 - 0.085 13.2 0.0 0.28 11.6 0.0 1.8 1 0 0 1 1 1 0 S-antigen protein US30 PF17624.2 KXS93767.1 - 0.021 13.9 0.0 0.022 13.8 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function S-antigen PF05756.11 KXS93768.1 - 0.076 13.4 0.0 0.26 11.7 0.0 1.8 1 0 0 1 1 1 0 S-antigen protein Glyco_hydro_65C PF03633.15 KXS93769.1 - 0.2 11.6 0.1 0.38 10.7 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, C-terminal domain DUF812 PF05667.11 KXS93771.1 - 0.15 10.9 1.6 2.2 7.1 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF812) BPS PF08947.10 KXS93771.1 - 0.28 11.0 4.5 0.1 12.4 1.1 2.0 2 0 0 2 2 2 0 BPS (Between PH and SH2) IATP PF04568.12 KXS93771.1 - 5.6 7.5 7.8 3.5 8.1 1.0 3.2 3 0 0 3 3 3 0 Mitochondrial ATPase inhibitor, IATP P16-Arc PF04699.14 KXS93772.1 - 6.4e-51 172.7 0.0 7.3e-51 172.6 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Cyclin_N PF00134.23 KXS93774.1 - 0.00013 21.7 0.0 0.0017 18.1 0.0 2.2 2 1 0 2 2 2 1 Cyclin, N-terminal domain TFIIB_C_1 PF18542.1 KXS93774.1 - 0.093 12.8 0.0 0.25 11.4 0.0 1.7 2 0 0 2 2 2 0 Transcription factor IIB C-terminal module 1 DUF713 PF05218.14 KXS93776.1 - 0.074 12.8 0.0 0.098 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF713) CN_hydrolase PF00795.22 KXS93777.1 - 1.1e-29 103.6 0.0 1.3e-29 103.3 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase MFS_1 PF07690.16 KXS93778.1 - 8.5e-36 123.6 23.4 1.7e-35 122.6 23.0 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Phage_holin_5_2 PF16079.5 KXS93778.1 - 8.1 6.9 9.0 5 7.5 0.1 3.9 3 2 2 5 5 5 0 Phage holin family Hol44, in holin superfamily V Paf67 PF10255.9 KXS93780.1 - 6.8e-154 512.7 0.0 7.9e-154 512.5 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 KXS93780.1 - 0.00079 19.4 0.1 0.0046 17.0 0.2 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KXS93780.1 - 0.0072 16.1 0.1 0.039 13.8 0.2 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat Amidase PF01425.21 KXS93788.1 - 3.8e-69 233.8 0.2 2e-66 224.8 0.0 2.1 2 0 0 2 2 2 2 Amidase FSH1 PF03959.13 KXS93790.1 - 4.8e-56 189.8 0.0 6.5e-56 189.3 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 KXS93790.1 - 0.01 15.4 0.0 0.026 14.0 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KXS93790.1 - 0.018 15.7 0.1 0.036 14.7 0.1 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KXS93790.1 - 0.2 11.5 0.1 43 3.8 0.0 3.0 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase SecE PF00584.20 KXS93791.1 - 2.5e-15 56.1 0.0 2.9e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex T4-Gluco-transf PF09198.10 KXS93793.1 - 0.2 11.3 0.0 0.43 10.2 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage T4 beta-glucosyltransferase NMO PF03060.15 KXS93794.1 - 2.3e-54 185.0 0.9 3.4e-54 184.5 0.9 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KXS93794.1 - 3.4e-13 49.3 2.8 3e-12 46.2 0.6 2.7 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KXS93794.1 - 1.7e-08 33.9 0.6 3.3e-08 33.0 0.6 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KXS93794.1 - 0.0001 21.6 0.1 0.00018 20.7 0.1 1.5 2 0 0 2 2 2 1 Conserved region in glutamate synthase DHO_dh PF01180.21 KXS93794.1 - 0.0014 17.9 0.1 0.0024 17.1 0.1 1.4 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase YadA_anchor PF03895.15 KXS93794.1 - 5.3 7.2 7.8 0.65 10.1 0.6 2.3 2 0 0 2 2 2 0 YadA-like membrane anchor domain Pterin_bind PF00809.22 KXS93795.1 - 3.9e-78 262.5 0.0 6.6e-78 261.7 0.0 1.4 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 KXS93795.1 - 1.4e-34 119.0 0.4 5.2e-34 117.1 0.0 2.3 2 0 0 2 2 2 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Pterin_bind PF00809.22 KXS93796.1 - 4.5e-78 262.3 0.0 7.7e-78 261.5 0.0 1.4 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 KXS93796.1 - 1.7e-34 118.7 0.4 5.9e-34 117.0 0.0 2.2 2 0 0 2 2 2 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) NIR_SIR PF01077.22 KXS93797.1 - 0.047 13.2 0.0 0.065 12.7 0.0 1.2 1 0 0 1 1 1 0 Nitrite and sulphite reductase 4Fe-4S domain ADD_DNMT3 PF17980.1 KXS93797.1 - 0.095 12.7 0.0 0.26 11.3 0.0 1.7 2 0 0 2 2 2 0 Cysteine rich ADD domain in DNMT3 Glyco_hydro_10 PF00331.20 KXS93801.1 - 2.2e-78 263.6 0.2 2.6e-78 263.3 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Glyco_transf_4 PF13439.6 KXS93801.1 - 0.15 12.1 0.0 2.7 8.0 0.0 2.2 2 0 0 2 2 2 0 Glycosyltransferase Family 4 HET PF06985.11 KXS93802.1 - 5.9e-11 42.9 8.7 2e-08 34.7 3.7 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF4048 PF13257.6 KXS93803.1 - 4.9e-58 197.0 20.8 4.9e-58 197.0 20.8 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4048) GrpE PF01025.19 KXS93803.1 - 0.16 11.6 0.6 0.41 10.3 0.3 1.7 2 0 0 2 2 2 0 GrpE SLX9 PF15341.6 KXS93803.1 - 9.6 6.6 11.5 0.33 11.3 2.2 2.8 2 1 1 3 3 3 0 Ribosome biogenesis protein SLX9 IFP_35_N PF07334.13 KXS93806.1 - 0.051 13.7 0.9 0.17 12.0 0.2 2.1 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus OxoGdeHyase_C PF16870.5 KXS93806.1 - 0.17 11.6 2.1 0.4 10.4 2.1 1.6 1 0 0 1 1 1 0 2-oxoglutarate dehydrogenase C-terminal DUF711 PF05167.12 KXS93806.1 - 0.18 10.7 0.0 0.23 10.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised ACR (DUF711) Abhydrolase_3 PF07859.13 KXS93807.1 - 2.1e-29 102.9 0.0 3e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXS93807.1 - 1.2e-11 44.1 0.0 1.6e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 KXS93807.1 - 0.046 13.0 0.0 0.076 12.3 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Tim17 PF02466.19 KXS93808.1 - 2.6e-38 130.8 10.5 3.5e-38 130.4 10.5 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF543 PF04418.12 KXS93808.1 - 0.00031 20.7 0.9 0.045 13.7 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF543) ABA_WDS PF02496.16 KXS93808.1 - 0.4 11.2 3.2 5.4 7.6 3.2 2.6 1 1 0 1 1 1 0 ABA/WDS induced protein F-box PF00646.33 KXS93809.1 - 4.7e-10 39.1 0.0 9.7e-10 38.1 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXS93809.1 - 5.2e-09 35.9 0.2 2.3e-08 33.8 0.0 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXS93810.1 - 4.7e-10 39.1 0.0 9.7e-10 38.1 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXS93810.1 - 5.2e-09 35.9 0.2 2.3e-08 33.8 0.0 2.1 2 0 0 2 2 2 1 F-box-like RNase_H2_suC PF08615.11 KXS93811.1 - 1.1e-17 64.5 2.2 2.6e-16 60.1 2.2 2.5 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) ABC2_membrane PF01061.24 KXS93812.1 - 7.3e-10 38.6 9.9 1e-09 38.1 9.9 1.2 1 0 0 1 1 1 1 ABC-2 type transporter C2-set PF05790.15 KXS93813.1 - 0.024 14.8 0.2 0.034 14.3 0.2 1.3 1 0 0 1 1 1 0 Immunoglobulin C2-set domain DUF285 PF03382.14 KXS93813.1 - 0.041 13.6 0.0 0.07 12.9 0.0 1.4 1 1 0 1 1 1 0 Mycoplasma protein of unknown function, DUF285 EF-hand_4 PF12763.7 KXS93814.1 - 0.058 13.4 0.0 0.19 11.7 0.0 1.7 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand PRIMA1 PF16101.5 KXS93815.1 - 0.42 10.7 9.0 0.7 9.9 9.0 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Glyco_transf_8 PF01501.20 KXS93816.1 - 5.1e-07 29.5 0.1 1.9e-06 27.6 0.1 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 KXS93816.1 - 0.017 14.5 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative Glyco_hydro_16 PF00722.21 KXS93817.1 - 1.8e-42 144.8 3.6 1.8e-42 144.8 3.6 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Ribosomal_L37 PF08561.10 KXS93818.1 - 1.2e-43 148.4 0.6 1.2e-43 148.4 0.6 1.7 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L37 Ndc1_Nup PF09531.10 KXS93818.1 - 0.12 11.0 4.0 0.12 11.0 4.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup 2OG-FeII_Oxy_2 PF13532.6 KXS93819.1 - 6.4e-29 101.5 0.0 1.3e-28 100.5 0.0 1.5 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily CBFB_NFYA PF02045.15 KXS93820.1 - 2.6e-28 98.4 4.3 5.6e-28 97.3 4.3 1.6 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B TFIIA PF03153.13 KXS93820.1 - 0.0015 18.6 30.9 0.0018 18.3 30.9 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF2457 PF10446.9 KXS93821.1 - 0.017 14.3 1.5 0.031 13.4 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF1408 PF07193.11 KXS93821.1 - 0.34 11.1 1.0 0.87 9.8 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1408) MetOD2 PF18548.1 KXS93826.1 - 0.026 14.6 0.1 0.044 13.9 0.1 1.4 1 0 0 1 1 1 0 Metanogen output domain 2 DUF4448 PF14610.6 KXS93829.1 - 0.011 15.6 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) CLN3 PF02487.17 KXS93829.1 - 0.17 10.9 0.0 0.17 10.9 0.0 1.5 2 0 0 2 2 2 0 CLN3 protein HUN PF08729.10 KXS93829.1 - 0.3 11.1 7.2 0.65 10.0 1.7 3.2 3 0 0 3 3 3 0 HPC2 and ubinuclein domain Gastrin PF00918.17 KXS93829.1 - 0.36 11.8 0.1 0.36 11.8 0.1 2.7 2 1 0 2 2 2 0 Gastrin/cholecystokinin family FAM176 PF14851.6 KXS93829.1 - 0.65 9.6 0.0 0.65 9.6 0.0 3.6 2 2 2 4 4 4 0 FAM176 family DUF3597 PF12200.8 KXS93829.1 - 6.3 7.3 7.2 0.74 10.4 0.9 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3597) TctB PF07331.11 KXS93830.1 - 0.065 13.5 0.1 0.1 12.8 0.1 1.2 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family adh_short PF00106.25 KXS93831.1 - 1.7e-22 79.8 0.0 2.3e-20 72.9 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS93831.1 - 2.2e-13 50.3 0.0 4.3e-12 46.1 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS93831.1 - 0.069 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 KR domain Methyltransf_16 PF10294.9 KXS93832.1 - 0.043 13.5 0.0 1.3 8.8 0.0 2.2 2 0 0 2 2 2 0 Lysine methyltransferase E1-E2_ATPase PF00122.20 KXS93833.1 - 3.4e-51 173.4 0.4 1.2e-50 171.5 0.4 2.0 1 0 0 1 1 1 1 E1-E2 ATPase HMA PF00403.26 KXS93833.1 - 8.6e-50 167.0 3.1 4.3e-13 49.5 0.6 4.4 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.26 KXS93833.1 - 2.7e-38 132.4 0.1 7.4e-38 130.9 0.1 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KXS93833.1 - 0.012 15.3 0.4 0.028 14.1 0.4 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase B12-binding PF02310.19 KXS93833.1 - 0.036 14.1 1.1 9.8 6.2 0.0 4.3 5 0 0 5 5 5 0 B12 binding domain Glyco_hydro_3_C PF01915.22 KXS93836.1 - 4.7e-48 163.9 0.0 7.6e-48 163.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXS93836.1 - 1.4e-21 77.2 0.0 9.3e-18 64.7 0.0 2.4 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXS93836.1 - 2.2e-17 62.9 0.1 4.6e-17 61.9 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PALP PF00291.25 KXS93838.1 - 2.9e-64 217.3 0.7 5.7e-64 216.3 0.7 1.4 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme BUD22 PF09073.10 KXS93841.1 - 0.012 15.0 11.1 0.022 14.1 11.1 1.5 1 0 0 1 1 1 0 BUD22 Gemini_AC4_5_2 PF08464.10 KXS93841.1 - 0.056 13.4 0.1 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 Geminivirus AC4/5 conserved region SDA1 PF05285.12 KXS93841.1 - 0.44 9.9 12.6 0.92 8.9 12.6 1.5 1 0 0 1 1 1 0 SDA1 CNRIP1 PF15043.6 KXS93842.1 - 0.024 14.2 0.0 0.052 13.1 0.0 1.6 2 0 0 2 2 2 0 CB1 cannabinoid receptor-interacting protein 1 Unstab_antitox PF09720.10 KXS93843.1 - 0.059 13.4 0.1 0.081 13.0 0.1 1.3 1 0 0 1 1 1 0 Putative addiction module component Rib PF08428.10 KXS93844.1 - 4.4 7.4 8.6 1.9 8.6 0.6 4.1 2 1 2 4 4 4 0 Rib/alpha-like repeat YL1 PF05764.13 KXS93845.1 - 0.0022 18.1 7.6 0.0028 17.8 7.6 1.1 1 0 0 1 1 1 1 YL1 nuclear protein SR-25 PF10500.9 KXS93845.1 - 0.067 12.8 11.4 0.093 12.3 11.4 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CCDC106 PF15794.5 KXS93845.1 - 0.25 11.0 5.8 0.84 9.3 6.0 1.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 CDC45 PF02724.14 KXS93845.1 - 2 6.6 9.5 2.6 6.2 9.5 1.1 1 0 0 1 1 1 0 CDC45-like protein YqfQ PF14181.6 KXS93845.1 - 4.4 7.5 8.0 6.4 6.9 8.0 1.1 1 0 0 1 1 1 0 YqfQ-like protein NARP1 PF12569.8 KXS93845.1 - 9.6 5.0 10.7 12 4.6 10.7 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Caps_synth PF05704.12 KXS93846.1 - 4.3e-10 39.4 0.6 2.6e-09 36.9 0.6 2.1 1 1 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.15 KXS93846.1 - 4.6e-05 24.0 0.0 0.00012 22.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif NAAA-beta PF15508.6 KXS93847.1 - 2.2e-12 47.1 0.0 4.5e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase LysM PF01476.20 KXS93848.1 - 0.0011 19.0 0.0 0.0086 16.1 0.0 2.3 2 0 0 2 2 2 1 LysM domain Cut12 PF11500.8 KXS93851.1 - 1.4e-22 80.2 17.8 5e-22 78.4 17.1 2.4 1 1 0 1 1 1 1 Spindle pole body formation-associated protein Atg14 PF10186.9 KXS93851.1 - 0.57 9.2 14.9 1.2 8.2 14.9 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2570 PF10828.8 KXS93851.1 - 0.73 9.7 5.8 1.9 8.4 5.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Spc7 PF08317.11 KXS93851.1 - 1.3 7.9 16.7 1.4 7.7 15.5 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4407 PF14362.6 KXS93851.1 - 1.4 8.2 12.3 3.1 7.1 12.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 KXS93851.1 - 2.5 7.6 9.7 5.3 6.5 9.7 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4446 PF14584.6 KXS93851.1 - 2.7 8.0 6.9 5.6 6.9 6.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DivIC PF04977.15 KXS93851.1 - 8.2 6.3 10.3 0.74 9.6 2.6 2.7 1 1 2 3 3 3 0 Septum formation initiator F-box-like PF12937.7 KXS93855.1 - 9e-05 22.3 0.1 0.00023 21.0 0.1 1.8 1 0 0 1 1 1 1 F-box-like PRIMA1 PF16101.5 KXS93855.1 - 1.1 9.3 11.9 12 5.9 0.1 2.4 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Glyco_hydro_2_C PF02836.17 KXS93856.1 - 2.4e-100 335.6 0.0 3.3e-100 335.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 KXS93856.1 - 7e-63 212.5 0.0 1.4e-62 211.5 0.0 1.5 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 KXS93856.1 - 5.7e-41 140.2 0.0 9.3e-40 136.3 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 KXS93856.1 - 1.2e-22 80.1 0.0 2.1e-21 76.2 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 KXS93856.1 - 3.9e-10 40.4 0.0 1.8e-09 38.3 0.0 2.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 KXS93856.1 - 0.0031 18.1 0.0 0.011 16.3 0.0 1.9 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain CBM60 PF16841.5 KXS93856.1 - 0.033 14.6 0.9 4 7.9 0.1 3.2 3 0 0 3 3 3 0 Ca-dependent carbohydrate-binding module xylan-binding MFS_1 PF07690.16 KXS93857.1 - 1.1e-33 116.7 34.5 1.1e-33 116.7 34.5 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1634 PF07843.11 KXS93857.1 - 0.039 14.0 3.0 0.1 12.7 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1634) Sugar_tr PF00083.24 KXS93858.1 - 4.4e-88 296.1 22.2 5.6e-88 295.8 22.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS93858.1 - 2.4e-33 115.5 31.7 9.4e-21 74.1 17.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KXS93858.1 - 0.00027 19.4 10.2 0.0059 15.0 1.4 2.9 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 KXS93859.1 - 2.2e-81 274.0 21.0 8.2e-80 268.8 15.2 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KXS93859.1 - 2.4e-34 118.8 23.6 3.2e-34 118.4 23.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 KXS93859.1 - 0.00057 18.3 11.4 0.0063 14.9 1.3 2.8 1 1 2 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family LacY_symp PF01306.19 KXS93859.1 - 0.0015 17.4 5.8 0.0038 16.1 0.7 2.2 2 0 0 2 2 2 2 LacY proton/sugar symporter TRI12 PF06609.13 KXS93859.1 - 0.025 13.0 4.3 0.032 12.7 3.0 1.5 1 1 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) Cupin_8 PF13621.6 KXS93861.1 - 6.3e-66 222.7 0.4 8.5e-66 222.2 0.4 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KXS93861.1 - 3.2e-05 23.6 0.0 0.012 15.1 0.0 2.4 2 1 0 2 2 2 2 Cupin superfamily protein QslA_E PF18226.1 KXS93861.1 - 0.068 13.1 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 LasR-specific antiactivator QslA chain E JmjC PF02373.22 KXS93861.1 - 0.091 13.2 0.0 17 5.9 0.0 3.2 3 0 0 3 3 3 0 JmjC domain, hydroxylase Sugar_tr PF00083.24 KXS93862.1 - 2.2e-81 274.0 21.0 8.2e-80 268.8 15.2 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KXS93862.1 - 2.4e-34 118.8 23.6 3.2e-34 118.4 23.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 KXS93862.1 - 0.00057 18.3 11.4 0.0063 14.9 1.3 2.8 1 1 2 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family LacY_symp PF01306.19 KXS93862.1 - 0.0015 17.4 5.8 0.0038 16.1 0.7 2.2 2 0 0 2 2 2 2 LacY proton/sugar symporter TRI12 PF06609.13 KXS93862.1 - 0.025 13.0 4.3 0.032 12.7 3.0 1.5 1 1 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXS93863.1 - 3.8e-89 299.6 23.3 4.9e-89 299.3 23.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS93863.1 - 7.7e-34 117.2 32.3 2.8e-22 79.2 17.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KXS93863.1 - 7.8e-05 21.2 10.6 0.006 14.9 1.4 2.9 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 KXS93864.1 - 1.5e-82 277.9 21.8 4.7e-81 273.0 13.8 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KXS93864.1 - 5.3e-35 121.0 23.6 6.9e-35 120.6 23.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 KXS93864.1 - 0.00014 20.3 11.6 0.0066 14.8 1.9 2.8 1 1 2 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family LacY_symp PF01306.19 KXS93864.1 - 0.0012 17.7 5.6 0.0037 16.1 0.7 2.2 2 0 0 2 2 2 2 LacY proton/sugar symporter TRI12 PF06609.13 KXS93864.1 - 0.021 13.2 4.4 0.021 13.2 3.3 1.5 1 1 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) Amidohydro_1 PF01979.20 KXS93865.1 - 1.3e-43 149.7 0.0 1.5e-43 149.5 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXS93865.1 - 2.7e-17 63.4 0.1 6.5e-11 42.4 0.0 2.5 2 1 0 2 2 2 2 Amidohydrolase family DeoC PF01791.9 KXS93865.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 DeoC/LacD family aldolase GAT PF03127.14 KXS93866.1 - 7.1e-19 67.9 0.5 7.1e-19 67.9 0.5 1.7 2 0 0 2 2 2 1 GAT domain VHS PF00790.19 KXS93866.1 - 0.0081 16.0 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 VHS domain FXMR_C2 PF16098.5 KXS93866.1 - 2.2 8.8 5.4 27 5.3 0.0 3.5 3 1 1 4 4 4 0 Fragile X-related mental retardation protein C-terminal region 2 Vault_4 PF17796.1 KXS93867.1 - 0.0079 16.2 0.0 0.018 15.1 0.0 1.6 1 0 0 1 1 1 1 Major Vault Protein repeat domain Trimer_CC PF08954.11 KXS93867.1 - 0.09 12.4 1.5 0.25 10.9 1.5 1.8 1 0 0 1 1 1 0 Trimerisation motif DUF1349 PF07081.11 KXS93867.1 - 0.095 12.4 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1349) Peptidase_M16_M PF16187.5 KXS93872.1 - 2.1e-94 315.9 0.2 3.9e-94 315.1 0.2 1.5 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 KXS93872.1 - 2.3e-31 109.2 0.5 8.8e-22 78.0 0.0 3.2 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KXS93872.1 - 3.1e-30 105.1 0.5 1.2e-29 103.2 0.5 2.1 1 1 0 1 1 1 1 Insulinase (Peptidase family M16) YppF PF14178.6 KXS93872.1 - 0.044 13.7 0.4 0.37 10.7 0.0 2.4 2 0 0 2 2 2 0 YppF-like protein BET PF17035.5 KXS93872.1 - 0.11 12.7 0.3 22 5.3 0.0 2.8 2 0 0 2 2 2 0 Bromodomain extra-terminal - transcription regulation Peptidase_M16_M PF16187.5 KXS93873.1 - 2.1e-94 315.9 0.2 3.9e-94 315.1 0.2 1.5 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 KXS93873.1 - 2.3e-31 109.2 0.5 8.8e-22 78.0 0.0 3.2 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KXS93873.1 - 3.1e-30 105.1 0.5 1.2e-29 103.2 0.5 2.1 1 1 0 1 1 1 1 Insulinase (Peptidase family M16) YppF PF14178.6 KXS93873.1 - 0.044 13.7 0.4 0.37 10.7 0.0 2.4 2 0 0 2 2 2 0 YppF-like protein BET PF17035.5 KXS93873.1 - 0.11 12.7 0.3 22 5.3 0.0 2.8 2 0 0 2 2 2 0 Bromodomain extra-terminal - transcription regulation SNF2_N PF00176.23 KXS93874.1 - 2.2e-53 181.2 0.3 1.9e-52 178.2 0.3 2.2 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXS93874.1 - 2.1e-16 60.3 0.0 9.8e-16 58.1 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain GFO_IDH_MocA_C PF02894.17 KXS93874.1 - 4.9e-15 55.6 0.3 1.3e-14 54.2 0.3 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.22 KXS93874.1 - 1.1e-14 55.2 0.0 2.7e-14 54.0 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold zf-C3HC4 PF00097.25 KXS93874.1 - 1.2e-08 34.7 4.0 1.2e-08 34.7 4.0 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 KXS93874.1 - 1.3e-07 31.8 0.0 3.2e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_34 PF13872.6 KXS93874.1 - 9.1e-05 21.5 0.0 0.00021 20.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 zf-C3HC4_2 PF13923.6 KXS93874.1 - 0.00027 20.7 4.8 0.00027 20.7 4.8 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXS93874.1 - 0.0011 18.9 1.1 0.0011 18.9 1.1 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KXS93874.1 - 0.0016 18.3 5.5 0.0016 18.3 5.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXS93874.1 - 0.0021 18.3 5.7 0.0021 18.3 5.7 2.5 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 KXS93874.1 - 0.0039 17.3 4.4 0.0039 17.3 4.4 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KXS93874.1 - 0.0069 16.3 5.8 0.0069 16.3 5.8 2.4 2 0 0 2 2 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KXS93874.1 - 0.03 14.2 5.5 0.076 12.9 5.5 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_Tnp_IS91 PF14319.6 KXS93874.1 - 0.52 10.4 13.8 0.037 14.1 2.3 2.5 2 0 0 2 2 2 0 Transposase zinc-binding domain p450 PF00067.22 KXS93875.1 - 3.2e-10 39.4 0.2 1.6e-07 30.5 0.0 2.9 1 1 1 2 2 2 2 Cytochrome P450 ATG22 PF11700.8 KXS93876.1 - 4.8e-52 177.2 27.4 6.2e-52 176.8 27.4 1.1 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like HET PF06985.11 KXS93877.1 - 1e-23 84.3 0.0 2e-23 83.4 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) eIF-5a PF01287.20 KXS93877.1 - 1.5e-06 28.2 0.1 2.9e-06 27.3 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Pectate_lyase_3 PF12708.7 KXS93879.1 - 2.7e-99 331.3 17.1 1.8e-85 286.1 4.4 3.2 4 0 0 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KXS93879.1 - 4.9e-09 35.8 1.0 0.0033 17.1 0.1 2.9 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase SnoaL_2 PF12680.7 KXS93880.1 - 0.0084 16.7 0.0 0.014 16.0 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain DUF2358 PF10184.9 KXS93880.1 - 0.015 15.5 0.0 0.024 14.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2358) DUF2358 PF10184.9 KXS93881.1 - 0.01 16.1 0.3 0.031 14.6 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2358) SnoaL_2 PF12680.7 KXS93881.1 - 0.01 16.5 0.0 0.019 15.6 0.0 1.4 1 0 0 1 1 1 0 SnoaL-like domain HMG_box_2 PF09011.10 KXS93882.1 - 0.036 14.6 3.7 0.036 14.6 1.8 2.0 1 1 0 1 1 1 0 HMG-box domain Haem_degrading PF03928.14 KXS93884.1 - 1.2e-30 106.0 0.2 1.4e-30 105.8 0.2 1.0 1 0 0 1 1 1 1 Haem-degrading Diacid_rec PF05651.13 KXS93884.1 - 0.11 12.2 0.4 0.11 12.2 0.4 1.5 2 0 0 2 2 2 0 Putative sugar diacid recognition HTH_32 PF13565.6 KXS93885.1 - 2.1e-07 31.4 0.0 0.0019 18.8 0.0 2.6 1 1 1 2 2 2 2 Homeodomain-like domain HTH_7 PF02796.15 KXS93885.1 - 2.9e-05 24.0 0.1 0.00062 19.8 0.0 2.7 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase PAX PF00292.18 KXS93885.1 - 0.021 14.7 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 'Paired box' domain HTH_23 PF13384.6 KXS93885.1 - 0.063 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain Trp_repressor PF01371.19 KXS93885.1 - 0.074 13.2 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Trp repressor protein HTH_29 PF13551.6 KXS93885.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix Sugar_tr PF00083.24 KXS93886.1 - 2.1e-133 445.5 26.7 2.4e-133 445.3 26.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS93886.1 - 3.4e-20 72.3 44.1 4.8e-20 71.8 36.7 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Shikimate_dh_N PF08501.11 KXS93887.1 - 7.8e-24 83.7 0.0 1.5e-23 82.8 0.0 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 KXS93887.1 - 0.0011 18.7 0.1 0.0023 17.7 0.1 1.5 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain OCD_Mu_crystall PF02423.15 KXS93887.1 - 0.016 14.1 0.0 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 KXS93887.1 - 0.021 14.9 0.0 0.036 14.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GARS_N PF02844.15 KXS93887.1 - 0.061 14.1 0.0 0.67 10.8 0.0 2.1 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, N domain NAD_binding_7 PF13241.6 KXS93887.1 - 0.14 12.6 0.0 0.23 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding GPS2_interact PF15784.5 KXS93888.1 - 0.15 12.5 0.1 0.62 10.5 0.0 2.1 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain Zn_clus PF00172.18 KXS93889.1 - 2.1e-08 34.1 11.1 4.7e-08 33.0 11.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXS93889.1 - 5.6e-08 32.1 0.0 8.6e-08 31.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain GFO_IDH_MocA PF01408.22 KXS93890.1 - 4e-31 108.3 0.4 6.2e-31 107.7 0.4 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KXS93890.1 - 1.1e-11 44.8 0.0 2e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.24 KXS93890.1 - 0.015 15.7 0.0 0.033 14.6 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain CoA_binding PF02629.19 KXS93890.1 - 0.093 13.4 0.0 0.17 12.6 0.0 1.4 1 0 0 1 1 1 0 CoA binding domain AP_endonuc_2 PF01261.24 KXS93891.1 - 5.4e-39 133.8 0.3 1.9e-38 132.1 0.1 1.7 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel Inositol_P PF00459.25 KXS93893.1 - 6.5e-63 212.8 0.5 1.2e-56 192.3 0.0 2.0 1 1 1 2 2 2 2 Inositol monophosphatase family Inositol_P PF00459.25 KXS93894.1 - 2.6e-77 260.0 0.0 2.9e-77 259.8 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family zinc_ribbon_10 PF10058.9 KXS93896.1 - 6.4e-20 70.6 0.2 1.1e-19 69.8 0.2 1.4 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein RMI1_N PF08585.12 KXS93896.1 - 0.02 14.7 0.1 0.033 13.9 0.1 1.3 1 0 0 1 1 1 0 RecQ mediated genome instability protein Ima1_N PF09779.9 KXS93896.1 - 0.28 12.0 1.6 1.1 10.1 0.2 2.5 1 1 1 2 2 2 0 Ima1 N-terminal domain Dyp_perox PF04261.12 KXS93897.1 - 4.1e-18 65.5 0.0 7.9e-16 57.9 0.0 3.4 2 1 0 2 2 2 1 Dyp-type peroxidase family CBS PF00571.28 KXS93898.1 - 4.1e-12 46.3 3.8 0.00012 22.5 0.2 4.4 5 0 0 5 5 5 3 CBS domain TPP_enzyme_N PF02776.18 KXS93899.1 - 4.8e-34 117.4 0.0 2.8e-30 105.2 0.1 2.6 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KXS93899.1 - 3.6e-19 69.1 0.0 6.4e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KXS93899.1 - 3.9e-08 33.1 0.0 8.5e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N PF02776.18 KXS93900.1 - 4.8e-34 117.4 0.0 2.8e-30 105.2 0.1 2.6 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KXS93900.1 - 3.6e-19 69.1 0.0 6.4e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KXS93900.1 - 3.9e-08 33.1 0.0 8.5e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain MFS_1 PF07690.16 KXS93901.1 - 3.7e-36 124.8 22.7 7.8e-36 123.7 20.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily FixQ PF05545.11 KXS93901.1 - 0.11 12.4 1.7 0.27 11.2 0.1 2.5 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ PRO8NT PF08082.11 KXS93901.1 - 0.23 11.4 0.0 0.42 10.5 0.0 1.3 1 0 0 1 1 1 0 PRO8NT (NUC069), PrP8 N-terminal domain MFS_1 PF07690.16 KXS93902.1 - 3.7e-36 124.8 22.7 7.8e-36 123.7 20.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily FixQ PF05545.11 KXS93902.1 - 0.11 12.4 1.7 0.27 11.2 0.1 2.5 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ PRO8NT PF08082.11 KXS93902.1 - 0.23 11.4 0.0 0.42 10.5 0.0 1.3 1 0 0 1 1 1 0 PRO8NT (NUC069), PrP8 N-terminal domain SLC3A2_N PF16028.5 KXS93904.1 - 0.11 12.1 0.1 0.22 11.1 0.1 1.5 1 0 0 1 1 1 0 Solute carrier family 3 member 2 N-terminus cPLA2_C2 PF18695.1 KXS93904.1 - 0.12 12.3 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Cytosolic phospholipases A2 C2-domain Mrpl_C PF18502.1 KXS93905.1 - 0.14 12.4 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 54S ribosomal protein L8 C-terminal domain Cupin_2 PF07883.11 KXS93906.1 - 6.4e-06 25.8 0.1 0.018 14.8 0.0 2.4 2 0 0 2 2 2 2 Cupin domain IBR PF01485.21 KXS93911.1 - 3e-05 24.2 6.0 3e-05 24.2 6.0 2.8 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain Sugar_tr PF00083.24 KXS93912.1 - 1.1e-91 307.9 22.0 1.4e-91 307.6 22.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS93912.1 - 1.5e-20 73.5 40.2 9.9e-14 51.0 16.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TAL_FSA PF00923.19 KXS93913.1 - 3.4e-34 118.5 0.0 6.1e-34 117.7 0.0 1.3 2 0 0 2 2 2 1 Transaldolase/Fructose-6-phosphate aldolase Acyl-CoA_dh_1 PF00441.24 KXS93914.1 - 2.8e-29 102.3 1.2 4.3e-29 101.7 1.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Ribosomal_L6 PF00347.23 KXS93914.1 - 9.2e-24 83.9 4.9 3.6e-12 46.8 1.4 2.4 2 0 0 2 2 2 2 Ribosomal protein L6 Acyl-CoA_dh_M PF02770.19 KXS93914.1 - 1.8e-23 82.5 0.0 4e-23 81.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KXS93914.1 - 5.4e-20 72.1 0.0 1.8e-19 70.4 0.0 2.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Bacteriocin_IIc PF10439.9 KXS93914.1 - 4 7.6 5.4 65 3.7 0.1 2.9 2 1 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide MBOAT PF03062.19 KXS93917.1 - 1.3e-35 123.4 20.6 3.1e-35 122.2 12.4 2.1 2 0 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family Pex14_N PF04695.13 KXS93917.1 - 0.0027 18.4 0.0 1.5 9.5 0.0 2.4 2 0 0 2 2 2 2 Peroxisomal membrane anchor protein (Pex14p) conserved region MBOAT PF03062.19 KXS93918.1 - 1.3e-35 123.4 20.6 3.1e-35 122.2 12.4 2.1 2 0 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family Pex14_N PF04695.13 KXS93918.1 - 0.0027 18.4 0.0 1.5 9.5 0.0 2.4 2 0 0 2 2 2 2 Peroxisomal membrane anchor protein (Pex14p) conserved region Glutaredoxin PF00462.24 KXS93919.1 - 6e-13 48.8 0.0 1.2e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin DSBA PF01323.20 KXS93919.1 - 0.049 13.4 0.1 4 7.2 0.1 2.5 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Histone_HNS PF00816.21 KXS93919.1 - 4 8.3 7.6 3.2 8.6 5.8 1.9 1 1 0 1 1 1 0 H-NS histone family Pkinase PF00069.25 KXS93920.1 - 2.2e-25 89.5 0.0 3.8e-23 82.2 0.0 2.8 1 1 0 1 1 1 1 Protein kinase domain Sulfotransfer_4 PF17784.1 KXS93921.1 - 2.6e-48 164.7 0.0 3.1e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KXS93921.1 - 0.02 15.3 0.0 0.03 14.7 0.0 1.4 1 0 0 1 1 1 0 Sulfotransferase family R3H-assoc PF13902.6 KXS93921.1 - 0.062 13.7 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 R3H-associated N-terminal domain DUF4032 PF13224.6 KXS93921.1 - 0.14 12.0 0.1 0.29 11.0 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4032) DUF1848 PF08902.11 KXS93921.1 - 0.16 11.7 0.1 0.22 11.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) p450 PF00067.22 KXS93922.1 - 3.8e-28 98.5 0.0 4.7e-27 94.8 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Methyltransf_31 PF13847.6 KXS93924.1 - 6.2e-27 94.3 0.0 1.1e-26 93.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS93924.1 - 2.6e-23 82.5 0.0 6.7e-23 81.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS93924.1 - 1e-21 77.3 0.0 2.1e-21 76.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS93924.1 - 6.2e-16 59.0 0.0 1.3e-15 57.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXS93924.1 - 6.1e-14 52.2 0.0 1.1e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXS93924.1 - 6.9e-13 48.5 0.0 1.5e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family UDPGT PF00201.18 KXS93924.1 - 6.8e-11 41.6 0.4 1.4e-08 34.0 0.1 2.4 2 0 0 2 2 2 2 UDP-glucoronosyl and UDP-glucosyl transferase Methyltransf_4 PF02390.17 KXS93924.1 - 1.3e-07 31.3 0.0 2.3e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.19 KXS93924.1 - 2.4e-07 30.7 0.0 4.3e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KXS93924.1 - 2.9e-07 30.2 0.0 5.9e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.6 KXS93924.1 - 5.9e-05 24.0 0.3 0.0014 19.6 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 KXS93924.1 - 0.00013 21.4 0.0 0.00024 20.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 KXS93924.1 - 0.00035 20.2 0.0 0.0011 18.7 0.0 1.8 2 0 0 2 2 1 1 Nodulation protein S (NodS) MetW PF07021.12 KXS93924.1 - 0.0031 17.1 0.0 0.0076 15.9 0.0 1.5 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW FtsJ PF01728.19 KXS93924.1 - 0.0053 16.9 0.0 0.014 15.5 0.0 1.7 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_9 PF08003.11 KXS93924.1 - 0.019 13.9 0.0 0.031 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 KXS93924.1 - 0.02 14.9 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Glyco_transf_4 PF13439.6 KXS93924.1 - 0.023 14.7 4.2 0.089 12.8 0.1 3.1 4 0 0 4 4 4 0 Glycosyltransferase Family 4 Methyltransf_2 PF00891.18 KXS93924.1 - 0.025 13.9 0.8 0.041 13.2 0.1 1.7 2 0 0 2 2 2 0 O-methyltransferase domain DUF1835 PF08874.10 KXS93924.1 - 0.027 14.7 0.0 0.3 11.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1835) Methyltr_RsmB-F PF01189.17 KXS93924.1 - 0.078 12.6 0.0 0.19 11.3 0.0 1.6 2 0 0 2 2 1 0 16S rRNA methyltransferase RsmB/F CMAS PF02353.20 KXS93924.1 - 0.082 12.2 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 KXS93924.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain p450 PF00067.22 KXS93925.1 - 3.9e-65 220.4 0.0 5e-65 220.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GIY-YIG PF01541.24 KXS93926.1 - 1e-13 51.4 0.0 3.1e-13 49.8 0.0 1.8 1 0 0 1 1 1 1 GIY-YIG catalytic domain FANCL_C PF11793.8 KXS93926.1 - 8.9e-05 22.6 4.3 0.00018 21.6 4.3 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-HC5HC2H PF13771.6 KXS93926.1 - 0.0014 18.8 3.9 0.003 17.8 3.9 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain PHD PF00628.29 KXS93926.1 - 0.0051 16.7 6.0 0.01 15.7 6.0 1.6 1 0 0 1 1 1 1 PHD-finger C1_2 PF03107.16 KXS93926.1 - 0.009 16.3 1.3 0.009 16.3 1.3 1.9 2 0 0 2 2 2 1 C1 domain PHD_Oberon PF07227.11 KXS93926.1 - 0.015 15.1 1.9 0.026 14.4 1.9 1.3 1 0 0 1 1 1 0 PHD - plant homeodomain finger protein zf-HC5HC2H_2 PF13832.6 KXS93926.1 - 0.024 14.8 3.3 0.048 13.8 3.3 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_2 PF13639.6 KXS93926.1 - 0.29 11.5 9.5 0.61 10.5 9.5 1.6 1 1 0 1 1 1 0 Ring finger domain zf-RING-like PF08746.11 KXS93926.1 - 0.92 9.9 6.7 0.2 12.0 2.2 2.2 2 1 0 2 2 2 0 RING-like domain LZ_Tnp_IS66 PF13007.7 KXS93926.1 - 3.9 8.3 9.8 2.1 9.2 0.4 2.6 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain GIY-YIG PF01541.24 KXS93927.1 - 1e-13 51.4 0.0 3.1e-13 49.8 0.0 1.8 1 0 0 1 1 1 1 GIY-YIG catalytic domain FANCL_C PF11793.8 KXS93927.1 - 8.9e-05 22.6 4.3 0.00018 21.6 4.3 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-HC5HC2H PF13771.6 KXS93927.1 - 0.0014 18.8 3.9 0.003 17.8 3.9 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain PHD PF00628.29 KXS93927.1 - 0.0051 16.7 6.0 0.01 15.7 6.0 1.6 1 0 0 1 1 1 1 PHD-finger C1_2 PF03107.16 KXS93927.1 - 0.009 16.3 1.3 0.009 16.3 1.3 1.9 2 0 0 2 2 2 1 C1 domain PHD_Oberon PF07227.11 KXS93927.1 - 0.015 15.1 1.9 0.026 14.4 1.9 1.3 1 0 0 1 1 1 0 PHD - plant homeodomain finger protein zf-HC5HC2H_2 PF13832.6 KXS93927.1 - 0.024 14.8 3.3 0.048 13.8 3.3 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_2 PF13639.6 KXS93927.1 - 0.29 11.5 9.5 0.61 10.5 9.5 1.6 1 1 0 1 1 1 0 Ring finger domain zf-RING-like PF08746.11 KXS93927.1 - 0.92 9.9 6.7 0.2 12.0 2.2 2.2 2 1 0 2 2 2 0 RING-like domain LZ_Tnp_IS66 PF13007.7 KXS93927.1 - 3.9 8.3 9.8 2.1 9.2 0.4 2.6 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain PLU-1 PF08429.11 KXS93928.1 - 2e-103 346.2 18.8 5.1e-102 341.5 17.2 2.2 2 0 0 2 2 2 1 PLU-1-like protein JmjC PF02373.22 KXS93928.1 - 7.1e-44 148.9 0.4 1.7e-43 147.6 0.4 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.21 KXS93928.1 - 1.9e-21 76.5 0.1 5.8e-21 75.0 0.1 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.17 KXS93928.1 - 1.3e-15 57.0 1.8 3.7e-15 55.6 1.8 1.9 1 0 0 1 1 1 1 jmjN domain PHD PF00628.29 KXS93928.1 - 2.8e-15 55.9 33.9 3.8e-09 36.3 9.2 2.9 3 0 0 3 3 3 2 PHD-finger zf-C5HC2 PF02928.16 KXS93928.1 - 3.8e-12 46.4 9.6 3.8e-12 46.4 9.6 2.3 2 0 0 2 2 2 1 C5HC2 zinc finger C1_1 PF00130.22 KXS93928.1 - 0.63 10.0 18.2 0.24 11.3 0.5 3.0 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_4 PF16866.5 KXS93928.1 - 4.5 7.4 23.0 0.48 10.6 5.0 2.7 2 0 0 2 2 2 0 PHD-finger TGT PF01702.18 KXS93929.1 - 5.3e-58 196.8 0.0 7e-58 196.5 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase MBOAT PF03062.19 KXS93932.1 - 2.4e-52 178.4 12.6 4.1e-52 177.7 12.6 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 KXS93932.1 - 0.27 11.5 3.4 0.67 10.3 3.4 1.7 1 0 0 1 1 1 0 Membrane bound O-acyl transferase family DJ-1_PfpI PF01965.24 KXS93934.1 - 3.9e-13 49.5 0.0 5.3e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KXS93934.1 - 0.0093 15.7 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 ThiJ/PfpI family-like BD_b_sandwich PF18820.1 KXS93934.1 - 0.16 12.0 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Bdellovibrio Beta-sandwich VHS PF00790.19 KXS93935.1 - 3.1e-46 156.7 0.0 1.2e-45 154.8 0.0 2.1 3 0 0 3 3 3 1 VHS domain GAT PF03127.14 KXS93935.1 - 3.8e-20 72.0 1.8 2.8e-19 69.2 0.1 3.0 4 0 0 4 4 4 1 GAT domain Alpha_adaptinC2 PF02883.20 KXS93935.1 - 4.1e-20 72.1 0.1 9.9e-20 70.9 0.1 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain GGA_N-GAT PF18308.1 KXS93935.1 - 5.2e-07 29.2 0.0 7.6e-06 25.4 0.0 2.7 2 0 0 2 2 2 1 GGA N-GAT domain MFS_1 PF07690.16 KXS93936.1 - 2.8e-38 131.8 17.7 3.7e-20 72.2 5.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS93936.1 - 7.7e-08 31.6 17.1 6.4e-06 25.3 6.4 3.0 2 1 1 4 4 4 2 Sugar (and other) transporter MFS_2 PF13347.6 KXS93936.1 - 1.2e-07 30.7 15.4 8.7e-07 27.8 4.5 2.8 2 1 1 3 3 3 3 MFS/sugar transport protein MFS_1_like PF12832.7 KXS93936.1 - 5e-06 25.6 7.8 5e-06 25.6 7.8 2.3 1 1 1 2 2 2 2 MFS_1 like family OATP PF03137.20 KXS93936.1 - 1.2e-05 23.8 11.9 0.0028 16.0 0.1 3.7 3 1 0 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family FAM176 PF14851.6 KXS93936.1 - 0.0088 15.7 1.3 0.87 9.2 0.0 2.8 3 0 0 3 3 3 1 FAM176 family MFS_3 PF05977.13 KXS93936.1 - 0.44 8.9 9.8 0.29 9.5 1.1 2.3 2 0 0 2 2 2 0 Transmembrane secretion effector MFS_1 PF07690.16 KXS93937.1 - 1.7e-35 122.6 15.7 1.7e-35 122.6 15.7 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DNA_pol_A_exo1 PF01612.20 KXS93938.1 - 4.3e-40 137.3 0.5 8.4e-40 136.3 0.5 1.5 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 KXS93938.1 - 5.8e-29 100.6 0.3 1.7e-28 99.1 0.0 2.0 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.23 KXS93938.1 - 1.5e-12 47.3 0.0 4.8e-12 45.7 0.0 2.0 1 0 0 1 1 1 1 HRDC domain Actin PF00022.19 KXS93940.1 - 2.3e-132 441.5 0.0 2.6e-132 441.3 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KXS93940.1 - 0.0053 15.6 0.0 1 8.1 0.0 2.4 3 0 0 3 3 3 2 MreB/Mbl protein Rad60-SLD PF11976.8 KXS93941.1 - 2.6e-18 65.6 0.0 2e-14 53.1 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like TUG-UBL1 PF11470.8 KXS93941.1 - 0.00033 20.8 0.0 0.0013 18.9 0.0 2.0 2 0 0 2 2 2 1 TUG ubiquitin-like domain ubiquitin PF00240.23 KXS93941.1 - 0.03 14.1 2.3 2.5 7.9 0.0 2.9 3 0 0 3 3 3 0 Ubiquitin family Shadoo PF14999.6 KXS93941.1 - 3.6 7.7 8.4 0.16 12.1 0.6 2.6 3 1 1 4 4 4 0 Shadow of prion protein, neuroprotective TPR_14 PF13428.6 KXS93945.1 - 2.9e-08 33.9 3.2 2 9.4 0.0 6.8 6 1 0 6 6 6 2 Tetratricopeptide repeat Suf PF05843.14 KXS93945.1 - 8e-05 22.8 7.9 0.0055 16.7 0.3 3.2 2 1 1 3 3 3 2 Suppressor of forked protein (Suf) TPR_17 PF13431.6 KXS93945.1 - 0.0064 16.8 0.0 25 5.6 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat HAT PF02184.16 KXS93945.1 - 3.2 7.8 19.6 10 6.2 0.2 6.7 6 0 0 6 6 6 0 HAT (Half-A-TPR) repeat Formyl_trans_N PF00551.19 KXS93948.1 - 3.7e-38 131.1 0.1 4.7e-38 130.7 0.1 1.1 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.25 KXS93948.1 - 5.3e-12 45.3 0.0 2.2e-11 43.3 0.0 2.0 2 0 0 2 2 2 1 ACT domain ACT_6 PF13740.6 KXS93948.1 - 7.8e-06 25.8 0.0 2.8e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 ACT domain F-box_4 PF15966.5 KXS93960.1 - 0.0084 16.0 0.0 0.02 14.7 0.0 1.7 1 0 0 1 1 1 1 F-box Relaxase PF03432.14 KXS93960.1 - 0.074 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain F-box PF00646.33 KXS93960.1 - 0.2 11.6 2.8 0.26 11.2 1.1 2.1 2 0 0 2 2 2 0 F-box domain HET PF06985.11 KXS93961.1 - 1.4e-33 116.3 2.0 2.3e-33 115.6 2.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PPS_PS PF02006.16 KXS93961.1 - 0.069 12.7 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Phosphopantothenate/pantothenate synthetase TraF PF13728.6 KXS93963.1 - 1.2 8.9 4.5 1.7 8.4 4.5 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Ribosomal_L30_N PF08079.12 KXS93965.1 - 2.6e-27 94.9 20.8 2.6e-27 94.9 20.8 1.8 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 KXS93965.1 - 8.8e-18 63.9 2.6 8.8e-18 63.9 2.6 2.0 3 0 0 3 3 3 1 Ribosomal protein L30p/L7e CSRNP_N PF16019.5 KXS93965.1 - 0.021 14.8 2.0 0.028 14.3 2.0 1.2 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Tipalpha PF16753.5 KXS93965.1 - 0.043 13.7 0.4 0.3 10.9 0.0 2.1 1 1 1 2 2 2 0 TNF-alpha-Inducing protein of Helicobacter EMC3_TMCO1 PF01956.16 KXS93965.1 - 0.55 9.9 2.0 0.71 9.6 2.0 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like EAP30 PF04157.16 KXS93966.1 - 1.4e-68 230.7 0.0 1.6e-68 230.6 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family MarR_2 PF12802.7 KXS93966.1 - 0.12 12.2 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 MarR family Lum_binding PF00677.17 KXS93967.1 - 8.4e-43 144.3 3.0 1.1e-20 73.4 0.3 2.2 2 0 0 2 2 2 2 Lumazine binding domain YabP PF07873.11 KXS93967.1 - 0.058 13.2 0.2 12 5.7 0.0 3.1 3 1 0 3 3 3 0 YabP family MapZ_C2 PF18708.1 KXS93967.1 - 0.1 12.9 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 MapZ extracellular C-terminal domain 2 UFD1 PF03152.14 KXS93968.1 - 9.8e-29 100.0 0.0 2.9e-15 56.2 0.0 3.3 2 1 1 3 3 3 3 Ubiquitin fusion degradation protein UFD1 AZUL PF16558.5 KXS93968.1 - 7.9e-07 29.2 0.1 7.9e-07 29.2 0.1 2.2 2 0 0 2 2 2 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A zinc_ribbon_4 PF13717.6 KXS93968.1 - 0.22 11.5 4.1 0.4 10.7 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain APH PF01636.23 KXS93969.1 - 1.2e-08 35.2 0.3 2.3e-08 34.3 0.3 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXS93969.1 - 8.2e-06 25.6 0.1 1.2e-05 25.0 0.1 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KXS93969.1 - 0.00042 20.0 0.0 0.93 9.1 0.0 2.2 1 1 1 2 2 2 2 RIO1 family Pkinase PF00069.25 KXS93969.1 - 0.14 11.5 0.0 0.44 9.9 0.0 1.7 1 1 1 2 2 2 0 Protein kinase domain EGF_2 PF07974.13 KXS93970.1 - 6.1e-05 23.3 3.0 0.00032 21.0 3.0 2.3 1 1 0 1 1 1 1 EGF-like domain EGF PF00008.27 KXS93970.1 - 3.8 7.9 6.8 0.45 10.9 1.3 2.4 2 1 0 2 2 2 0 EGF-like domain Rieske PF00355.26 KXS93971.1 - 0.17 11.9 4.4 0.15 12.0 3.6 1.4 1 1 0 1 1 1 0 Rieske [2Fe-2S] domain DUF2235 PF09994.9 KXS93978.1 - 3.2e-80 269.6 0.0 4.1e-80 269.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) CorA PF01544.18 KXS93979.1 - 1.2 8.4 10.5 74 2.5 10.4 2.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein CorA PF01544.18 KXS93980.1 - 1.2 8.4 10.5 74 2.5 10.4 2.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein CorA PF01544.18 KXS93982.1 - 1.2 8.4 10.5 74 2.5 10.4 2.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein FMN_dh PF01070.18 KXS93983.1 - 1.8e-111 372.5 0.0 2.4e-111 372.1 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KXS93983.1 - 3.4e-05 23.0 0.5 7.2e-05 21.9 0.2 1.6 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 KXS93983.1 - 3.4e-05 23.3 0.3 0.26 10.6 0.0 2.6 3 0 0 3 3 3 2 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.17 KXS93983.1 - 0.0003 20.0 0.4 0.00043 19.5 0.4 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 KXS93983.1 - 0.037 13.4 0.9 0.065 12.6 0.9 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase Sugar_tr PF00083.24 KXS93984.1 - 1.7e-63 215.1 7.7 2.2e-63 214.7 7.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS93984.1 - 7.7e-20 71.1 8.9 9.5e-20 70.8 8.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KXS93984.1 - 0.0018 16.8 0.8 0.0026 16.3 0.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KXS93991.1 - 2.3e-12 46.5 55.6 7.3e-08 31.7 28.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3481 PF11980.8 KXS93991.1 - 0.7 9.6 3.4 0.64 9.8 0.9 2.3 1 1 1 2 2 2 0 C-terminal domain of neuropilin glycoprotein p450 PF00067.22 KXS93992.1 - 1.8e-31 109.4 0.0 2e-31 109.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Prominin PF05478.11 KXS93992.1 - 0.21 9.5 0.0 0.27 9.1 0.0 1.1 1 0 0 1 1 1 0 Prominin CoA_transf_3 PF02515.17 KXS93993.1 - 2.1e-82 277.2 0.0 2.4e-82 277.0 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III CoA_transf_3 PF02515.17 KXS93994.1 - 5.2e-129 430.6 0.0 5.9e-129 430.4 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III Bud13 PF09736.9 KXS93995.1 - 3.7e-49 166.9 18.7 3.7e-49 166.9 18.7 3.2 2 1 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex AAA_11 PF13086.6 KXS93995.1 - 0.014 15.2 9.4 0.021 14.6 9.4 1.3 1 0 0 1 1 1 0 AAA domain zf-RRPl_C4 PF17026.5 KXS93996.1 - 0.11 12.7 0.2 0.18 11.9 0.2 1.3 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type p450 PF00067.22 KXS93997.1 - 5e-21 75.0 0.0 3.7e-20 72.1 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 DNA_binding_1 PF01035.20 KXS93998.1 - 1.6e-09 37.7 1.3 7.4e-09 35.6 1.3 2.1 1 1 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain OS-D PF03392.13 KXS93998.1 - 0.039 14.1 0.2 0.058 13.5 0.2 1.2 1 0 0 1 1 1 0 Insect pheromone-binding family, A10/OS-D Folate_carrier PF01770.18 KXS93998.1 - 0.079 11.7 0.3 0.093 11.5 0.3 1.1 1 0 0 1 1 1 0 Reduced folate carrier HRI1 PF16815.5 KXS94000.1 - 1.5e-40 139.3 0.0 1.7e-40 139.1 0.0 1.0 1 0 0 1 1 1 1 Protein HRI1 ACTH_assoc PF16102.5 KXS94003.1 - 0.044 14.6 0.0 10 7.1 0.0 2.1 2 0 0 2 2 2 0 ACTH-associated domain PI31_Prot_N PF11566.8 KXS94006.1 - 4.7e-54 182.6 0.0 5.7e-54 182.3 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 KXS94006.1 - 4e-17 63.2 19.3 4e-17 63.2 19.3 3.0 2 1 0 2 2 2 1 PI31 proteasome regulator zf-C2H2 PF00096.26 KXS94007.1 - 1.3e-10 41.1 18.1 0.00024 21.4 2.2 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS94007.1 - 1.8e-09 37.6 15.6 0.0077 17.0 1.5 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KXS94007.1 - 0.001 19.0 0.3 0.001 19.0 0.3 2.7 3 0 0 3 3 3 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXS94007.1 - 0.0028 18.0 20.3 0.038 14.4 0.6 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-Di19 PF05605.12 KXS94007.1 - 0.024 14.9 3.2 0.024 14.9 3.2 2.5 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 KXS94007.1 - 0.39 10.5 8.3 1.9 8.3 0.6 3.5 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 KXS94007.1 - 0.44 10.3 3.1 20 5.1 0.0 3.1 3 0 0 3 3 3 0 C2H2-type zinc-finger domain GAGA PF09237.11 KXS94007.1 - 0.63 9.9 5.3 3.8 7.4 0.0 3.4 1 1 2 3 3 3 0 GAGA factor zf-met PF12874.7 KXS94007.1 - 0.9 10.0 5.1 42 4.7 0.0 3.9 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KXS94007.1 - 0.99 9.8 6.8 13 6.1 0.1 2.6 1 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Git3 PF11710.8 KXS94008.1 - 1.8e-51 174.8 12.7 1.8e-51 174.8 12.7 1.8 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 KXS94008.1 - 1.5e-24 85.9 2.6 3.5e-24 84.6 2.6 1.7 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term PalH PF08733.10 KXS94010.1 - 0.045 12.8 0.5 0.05 12.6 0.5 1.1 1 0 0 1 1 1 0 PalH/RIM21 P19Arf_N PF07392.12 KXS94010.1 - 0.07 13.6 0.2 0.22 12.0 0.2 1.9 1 1 0 1 1 1 0 Cyclin-dependent kinase inhibitor 2a p19Arf N-terminus DUF4229 PF14012.6 KXS94010.1 - 0.19 11.8 0.2 0.19 11.8 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) AMP-binding PF00501.28 KXS94018.1 - 1.8e-78 264.0 0.0 3.8e-78 263.0 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 KXS94018.1 - 1.1e-70 238.1 0.1 1.9e-70 237.4 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KXS94018.1 - 3.7e-52 176.9 0.3 9.3e-50 169.0 0.1 2.5 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 KXS94018.1 - 1.9e-49 168.9 1.3 3.6e-49 168.0 1.3 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 KXS94018.1 - 4.2e-34 118.1 0.2 8.3e-34 117.2 0.2 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Condensation PF00668.20 KXS94018.1 - 6e-33 114.2 0.0 3.6e-19 68.8 0.1 2.3 2 0 0 2 2 2 2 Condensation domain NAD_binding_4 PF07993.12 KXS94018.1 - 3.5e-29 101.8 0.0 8.7e-29 100.5 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein Ketoacyl-synt_C PF02801.22 KXS94018.1 - 1.5e-28 99.2 1.1 3e-28 98.2 0.2 2.1 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 KXS94018.1 - 1.1e-18 67.5 0.0 5.3e-15 55.4 0.0 2.7 2 0 0 2 2 2 2 short chain dehydrogenase Methyltransf_12 PF08242.12 KXS94018.1 - 1.8e-17 63.9 0.0 8.4e-17 61.7 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KXS94018.1 - 3.8e-16 59.2 0.8 2.1e-08 34.4 0.1 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_23 PF13489.6 KXS94018.1 - 2.1e-12 47.2 0.0 4.7e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KXS94018.1 - 6.4e-12 45.9 0.0 1.8e-11 44.5 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 KXS94018.1 - 4.3e-11 43.4 0.0 2.3e-10 41.1 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS94018.1 - 4.6e-11 43.2 0.0 2.5e-10 40.8 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain 3Beta_HSD PF01073.19 KXS94018.1 - 3.4e-09 36.1 0.0 5.3e-08 32.2 0.0 2.5 3 0 0 3 3 3 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_31 PF13847.6 KXS94018.1 - 3.3e-06 27.0 0.0 8.3e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 KXS94018.1 - 1.3e-05 24.9 1.6 6.2e-05 22.7 0.0 2.6 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase Thiolase_N PF00108.23 KXS94018.1 - 0.0001 21.8 0.0 0.00025 20.5 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.18 KXS94018.1 - 0.00011 21.6 0.0 0.00023 20.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Polysacc_synt_2 PF02719.15 KXS94018.1 - 0.00018 20.7 0.0 0.001 18.3 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NodS PF05401.11 KXS94018.1 - 0.0022 17.7 0.0 0.0049 16.5 0.0 1.5 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_2 PF00891.18 KXS94018.1 - 0.0026 17.1 0.0 0.0048 16.2 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain AMP-binding_C PF13193.6 KXS94018.1 - 0.13 13.3 0.0 0.56 11.2 0.0 2.2 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 KXS94019.1 - 4e-34 118.1 48.6 4e-34 118.1 48.6 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS94019.1 - 0.00033 19.7 36.4 0.0085 15.0 19.8 3.5 1 1 0 2 2 2 2 Sugar (and other) transporter Sugar_tr PF00083.24 KXS94024.1 - 8.5e-124 413.8 22.1 9.6e-124 413.7 22.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS94024.1 - 2.1e-29 102.6 47.7 2.1e-25 89.4 25.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SirB PF04247.12 KXS94024.1 - 0.12 12.5 2.5 15 5.7 0.1 3.2 4 0 0 4 4 4 0 Invasion gene expression up-regulator, SirB Myb_DNA-binding PF00249.31 KXS94025.1 - 8.1e-08 32.3 2.2 1.2e-05 25.4 0.2 2.6 3 0 0 3 3 3 2 Myb-like DNA-binding domain HTH_38 PF13936.6 KXS94025.1 - 1.3e-05 24.9 0.1 0.058 13.2 0.0 3.3 3 0 0 3 3 3 2 Helix-turn-helix domain Myb_DNA-bind_6 PF13921.6 KXS94025.1 - 1.4e-05 25.3 0.1 0.14 12.5 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain HTH_7 PF02796.15 KXS94025.1 - 0.0012 18.8 0.0 0.91 9.6 0.0 3.2 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 KXS94025.1 - 0.0046 16.7 1.0 0.48 10.3 0.1 3.6 3 1 1 4 4 4 1 Homeodomain-like domain GcrA PF07750.11 KXS94025.1 - 0.022 15.2 0.8 22 5.4 0.0 3.0 3 0 0 3 3 3 0 GcrA cell cycle regulator Glyco_hydro_3_C PF01915.22 KXS94026.1 - 3.8e-47 160.9 0.0 6.7e-47 160.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KXS94026.1 - 3.3e-22 78.4 0.0 6.2e-22 77.5 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3 PF00933.21 KXS94026.1 - 9.6e-21 74.5 0.0 2.4e-20 73.2 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain CD99L2 PF12301.8 KXS94026.1 - 0.044 14.1 0.5 0.08 13.2 0.5 1.3 1 0 0 1 1 1 0 CD99 antigen like protein 2 MFS_1 PF07690.16 KXS94027.1 - 1.6e-39 135.8 20.3 1.6e-39 135.8 20.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS94027.1 - 1.5e-08 33.9 0.1 1.5e-08 33.9 0.1 3.0 3 0 0 3 3 3 1 Sugar (and other) transporter DUF3149 PF11346.8 KXS94027.1 - 0.077 12.6 0.9 0.32 10.6 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) DUF5090 PF17009.5 KXS94027.1 - 0.22 11.5 1.5 7.6 6.5 0.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5090) FA_desaturase PF00487.24 KXS94027.1 - 4 7.2 14.1 0.19 11.5 1.4 2.9 3 0 0 3 3 3 0 Fatty acid desaturase Pkinase PF00069.25 KXS94028.1 - 8.6e-16 58.1 0.0 1.2e-14 54.3 0.0 2.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS94028.1 - 2.7e-05 23.6 0.0 0.00015 21.2 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase PilJ PF13675.6 KXS94028.1 - 0.14 12.2 3.1 3.7 7.6 0.7 3.2 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term PEMT PF04191.13 KXS94029.1 - 0.063 13.7 0.1 0.11 12.9 0.1 1.4 1 0 0 1 1 1 0 Phospholipid methyltransferase Ank_4 PF13637.6 KXS94030.1 - 2.5e-10 40.7 0.4 0.00013 22.4 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS94030.1 - 4.9e-09 35.7 1.2 0.014 15.8 0.1 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 KXS94030.1 - 2.9e-07 31.0 0.1 0.029 14.9 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KXS94030.1 - 1e-05 25.7 1.3 0.54 10.8 0.1 3.7 4 0 0 4 4 3 2 Ankyrin repeat KilA-N PF04383.13 KXS94030.1 - 0.00028 20.7 0.1 0.0038 17.1 0.1 2.4 1 1 0 1 1 1 1 KilA-N domain Ank_5 PF13857.6 KXS94030.1 - 0.00029 21.1 1.3 0.67 10.4 0.0 3.8 2 1 1 3 3 3 1 Ankyrin repeats (many copies) HpcH_HpaI PF03328.14 KXS94030.1 - 0.043 13.0 0.1 0.096 11.8 0.1 1.5 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family DUF16 PF01519.16 KXS94030.1 - 0.75 10.3 7.7 0.57 10.7 3.7 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF16 Dynactin_p22 PF07426.11 KXS94030.1 - 3.5 7.5 12.0 0.59 10.0 0.6 2.3 2 0 0 2 2 2 0 Dynactin subunit p22 ZapB PF06005.12 KXS94030.1 - 4.8 7.7 14.6 0.66 10.5 0.2 2.7 2 0 0 2 2 2 0 Cell division protein ZapB FliD_C PF07195.12 KXS94030.1 - 5.2 6.4 7.5 6.8 6.0 0.6 2.3 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Prefoldin PF02996.17 KXS94030.1 - 9.7 6.1 11.9 39 4.2 6.7 2.8 1 1 2 3 3 3 0 Prefoldin subunit Zn_clus PF00172.18 KXS94032.1 - 0.017 15.2 13.5 0.065 13.4 13.5 2.0 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C4H2 PF10146.9 KXS94033.1 - 0.00093 19.6 4.5 0.0011 19.4 4.5 1.2 1 0 0 1 1 1 1 Zinc finger-containing protein HMMR_C PF15908.5 KXS94033.1 - 0.0014 18.9 4.2 0.004 17.4 4.2 1.9 1 1 0 1 1 1 1 Hyaluronan mediated motility receptor C-terminal DUF1759 PF03564.15 KXS94033.1 - 0.014 15.3 1.1 0.018 15.0 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) DUF3972 PF13118.6 KXS94033.1 - 0.025 15.0 5.3 1.9 9.0 0.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3972) DUF5082 PF16888.5 KXS94033.1 - 0.044 14.1 5.5 0.087 13.1 4.8 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) Sec8_exocyst PF04048.14 KXS94033.1 - 0.058 13.3 2.5 0.087 12.7 1.5 1.8 1 1 0 1 1 1 0 Sec8 exocyst complex component specific domain TMF_DNA_bd PF12329.8 KXS94033.1 - 0.1 12.6 9.3 0.3 11.1 3.6 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding SlyX PF04102.12 KXS94033.1 - 0.12 13.0 12.2 0.2 12.3 5.6 2.8 1 1 2 3 3 3 0 SlyX Mto2_bdg PF12808.7 KXS94033.1 - 0.12 12.7 5.0 0.56 10.6 0.6 3.1 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region His_binding PF02098.16 KXS94033.1 - 0.13 12.3 0.1 0.15 12.1 0.1 1.2 1 0 0 1 1 1 0 Tick histamine binding protein Exonuc_VII_L PF02601.15 KXS94033.1 - 0.25 10.9 5.0 0.28 10.7 5.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Sec2p PF06428.11 KXS94033.1 - 0.32 11.0 7.9 0.27 11.2 3.5 2.4 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p HALZ PF02183.18 KXS94033.1 - 0.39 11.0 5.0 1.8 8.9 0.1 2.9 4 0 0 4 4 3 0 Homeobox associated leucine zipper Spc7 PF08317.11 KXS94033.1 - 0.6 8.9 10.1 0.41 9.5 6.6 1.8 1 1 2 3 3 3 0 Spc7 kinetochore protein TBCA PF02970.16 KXS94033.1 - 0.77 10.1 9.0 1.5 9.2 7.8 2.1 1 1 1 2 2 2 0 Tubulin binding cofactor A DivIC PF04977.15 KXS94033.1 - 0.92 9.3 12.5 13 5.6 4.6 3.3 2 1 1 3 3 3 0 Septum formation initiator FOXP-CC PF16159.5 KXS94033.1 - 1.2 9.9 6.0 7.6 7.2 2.0 2.4 1 1 1 2 2 2 0 FOXP coiled-coil domain PRKG1_interact PF15898.5 KXS94033.1 - 1.2 10.0 9.0 0.78 10.7 3.9 2.2 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain CC2-LZ PF16516.5 KXS94033.1 - 1.4 9.3 9.2 1 9.7 5.3 2.4 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator CENP-Q PF13094.6 KXS94033.1 - 1.7 8.8 11.8 26 5.0 11.8 2.4 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit CENP-F_leu_zip PF10473.9 KXS94033.1 - 1.7 8.7 11.1 1.6 8.7 0.7 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4094 PF13334.6 KXS94033.1 - 1.7 9.1 4.4 19 5.7 4.4 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) NRBF2 PF08961.10 KXS94033.1 - 1.8 8.1 7.9 2.4 7.7 0.8 2.6 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator YabA PF06156.13 KXS94033.1 - 3.8 8.2 7.9 1.2 9.8 0.3 2.2 1 1 0 2 2 2 0 Initiation control protein YabA XhlA PF10779.9 KXS94033.1 - 4.7 7.5 5.5 3.2 8.0 2.7 2.0 2 0 0 2 2 2 0 Haemolysin XhlA UPF0242 PF06785.11 KXS94033.1 - 7.8 6.6 11.1 41 4.2 11.1 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus bZIP_2 PF07716.15 KXS94033.1 - 9.2 6.4 12.3 7.5 6.7 0.7 3.4 3 1 0 3 3 3 0 Basic region leucine zipper DUF1534 PF07551.11 KXS94034.1 - 0.011 15.5 0.2 0.023 14.5 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1534) eIF_4EBP PF05456.11 KXS94034.1 - 0.11 12.4 0.1 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Complex1_LYR PF05347.15 KXS94035.1 - 0.077 13.1 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 Complex 1 protein (LYR family) Complex1_LYR PF05347.15 KXS94036.1 - 0.077 13.1 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 Complex 1 protein (LYR family) PHD PF00628.29 KXS94043.1 - 1.4e-05 24.9 8.3 2.4e-05 24.2 8.3 1.4 1 0 0 1 1 1 1 PHD-finger zf-RING_2 PF13639.6 KXS94043.1 - 0.0019 18.5 5.9 0.0038 17.5 5.9 1.5 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 KXS94043.1 - 0.04 14.1 5.0 0.065 13.4 5.0 1.3 1 0 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 KXS94043.1 - 0.052 13.7 10.1 0.087 13.0 10.1 1.4 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.6 KXS94043.1 - 1.3 9.0 8.6 0.1 12.5 2.9 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 C1_1 PF00130.22 KXS94043.1 - 2.4 8.1 8.5 0.58 10.1 3.9 2.1 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RVT_1 PF00078.27 KXS94044.1 - 1.3e-05 24.8 0.0 2.3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 KXS94044.1 - 0.16 12.3 0.1 0.66 10.3 0.1 2.1 1 1 0 1 1 1 0 RNase H-like domain found in reverse transcriptase eIF3m_C_helix PF18005.1 KXS94045.1 - 0.049 13.3 1.9 0.13 12.0 1.9 1.7 1 0 0 1 1 1 0 eIF3 subunit M, C-terminal helix SDA1 PF05285.12 KXS94045.1 - 1.1 8.6 7.5 1.8 7.9 7.5 1.3 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 KXS94045.1 - 1.9 7.7 11.2 3.2 7.0 11.2 1.3 1 0 0 1 1 1 0 BUD22 GCD14 PF08704.10 KXS94046.1 - 9.3e-65 218.7 7.9 2.4e-64 217.3 1.0 2.6 2 1 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit Rxt3 PF08642.10 KXS94046.1 - 0.45 11.3 2.9 1.8 9.3 0.3 2.3 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 MSA_2 PF00985.17 KXS94046.1 - 1.4 9.2 6.7 3.8 7.8 2.1 2.2 2 0 0 2 2 2 0 Merozoite Surface Antigen 2 (MSA-2) family RNA_pol_Rpc4 PF05132.14 KXS94046.1 - 5.1 7.5 8.8 2.2 8.7 0.5 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 FAR1 PF03101.15 KXS94047.1 - 3.8e-09 37.1 2.4 1.3e-08 35.4 2.4 1.9 1 0 0 1 1 1 1 FAR1 DNA-binding domain Zn_clus PF00172.18 KXS94047.1 - 1.5e-06 28.2 11.8 2.9e-06 27.3 11.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Edc3_linker PF16598.5 KXS94047.1 - 0.47 11.1 5.4 19 6.0 1.3 3.5 3 0 0 3 3 3 0 Linker region of enhancer of mRNA-decapping protein 3 CENP-B_dimeris PF09026.10 KXS94047.1 - 6.1 7.3 8.1 13 6.2 7.5 1.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Glyco_hydro_31 PF01055.26 KXS94048.1 - 6.2e-90 302.5 7.9 1e-89 301.8 7.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 hDGE_amylase PF14701.6 KXS94049.1 - 4.7e-176 586.2 0.0 6.3e-176 585.8 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 KXS94049.1 - 8.5e-118 393.6 0.0 1.4e-117 392.9 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 KXS94049.1 - 2.4e-83 279.7 0.0 4.1e-83 278.9 0.0 1.4 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 KXS94049.1 - 3.8e-30 103.9 0.1 1.1e-29 102.4 0.1 1.9 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.24 KXS94049.1 - 0.00014 21.6 0.2 0.0003 20.4 0.2 1.5 1 0 0 1 1 1 1 Alpha amylase, catalytic domain MFS_1 PF07690.16 KXS94050.1 - 2.2e-37 128.8 39.0 2.8e-36 125.2 37.1 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS94050.1 - 3.7e-15 55.8 11.7 3.7e-15 55.8 11.7 2.9 3 0 0 3 3 3 2 Sugar (and other) transporter Bax1-I PF01027.20 KXS94050.1 - 4.3 7.1 29.6 0.63 9.8 7.9 4.1 4 0 0 4 4 4 0 Inhibitor of apoptosis-promoting Bax1 Cutinase PF01083.22 KXS94052.1 - 1.6e-42 145.5 4.8 2.1e-42 145.1 4.8 1.1 1 0 0 1 1 1 1 Cutinase VirJ PF06057.11 KXS94052.1 - 0.0022 17.9 0.0 0.0035 17.3 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) PE-PPE PF08237.11 KXS94052.1 - 0.012 15.1 0.3 0.018 14.6 0.3 1.2 1 0 0 1 1 1 0 PE-PPE domain SAD_SRA PF02182.17 KXS94053.1 - 3.5e-23 82.0 0.0 4.9e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 SAD/SRA domain DUF2285 PF10074.9 KXS94054.1 - 0.031 14.9 0.2 4.2 8.1 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2285) Translin PF01997.16 KXS94054.1 - 0.033 14.2 0.4 0.048 13.6 0.4 1.2 1 0 0 1 1 1 0 Translin family SKG6 PF08693.10 KXS94055.1 - 2.5e-06 26.8 3.4 4.2e-06 26.1 3.4 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain VSP PF03302.13 KXS94055.1 - 0.012 14.4 0.6 0.012 14.4 0.6 1.7 3 0 0 3 3 3 0 Giardia variant-specific surface protein EphA2_TM PF14575.6 KXS94055.1 - 0.094 13.6 0.0 0.14 13.0 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 KXS94055.1 - 0.12 12.3 0.3 0.23 11.4 0.3 1.4 1 0 0 1 1 1 0 Syndecan domain Ras PF00071.22 KXS94056.1 - 2.8e-39 134.3 0.0 1.4e-36 125.6 0.0 2.0 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KXS94056.1 - 1.6e-31 109.1 0.0 2.4e-31 108.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXS94056.1 - 8.5e-13 48.1 0.0 1.6e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KXS94056.1 - 1.9e-05 24.7 0.0 3.3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KXS94056.1 - 0.00095 18.6 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 KXS94056.1 - 0.0016 18.8 0.0 0.0026 18.2 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 KXS94056.1 - 0.0065 15.9 0.0 0.0087 15.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Septin PF00735.18 KXS94056.1 - 0.0078 15.5 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Septin NACHT PF05729.12 KXS94056.1 - 0.012 15.5 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 KXS94056.1 - 0.031 14.6 0.0 0.14 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 KXS94056.1 - 0.049 13.4 0.0 0.31 10.8 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 KXS94056.1 - 0.056 13.3 0.3 0.15 12.0 0.2 1.8 1 1 0 1 1 1 0 RsgA GTPase AAA_24 PF13479.6 KXS94056.1 - 0.06 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 KXS94056.1 - 0.079 12.5 0.0 0.62 9.6 0.0 2.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KXS94056.1 - 0.11 12.5 0.0 0.4 10.7 0.0 1.8 2 0 0 2 2 2 0 Dynamin family ATPase_2 PF01637.18 KXS94056.1 - 0.2 11.6 0.0 0.44 10.4 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Flavin_Reduct PF01613.18 KXS94057.1 - 9.6e-19 67.9 0.3 1.4e-18 67.4 0.3 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Tad PF13400.6 KXS94059.1 - 0.34 11.2 0.9 0.69 10.3 0.9 1.5 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like DAGK_cat PF00781.24 KXS94060.1 - 9.6e-15 54.3 0.0 1.6e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DUF3429 PF11911.8 KXS94065.1 - 4.4e-42 143.8 10.9 5.8e-42 143.4 10.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) Sugar_tr PF00083.24 KXS94066.1 - 0.013 14.4 5.4 0.022 13.6 5.5 1.3 1 1 0 1 1 1 0 Sugar (and other) transporter FTSW_RODA_SPOVE PF01098.19 KXS94066.1 - 0.047 12.7 5.0 0.056 12.4 5.0 1.1 1 0 0 1 1 1 0 Cell cycle protein FSAP_sig_propep PF03032.15 KXS94066.1 - 4.6 7.4 7.1 7.4 6.7 0.3 2.7 2 0 0 2 2 2 0 Frog skin active peptide family signal and propeptide 4HBT_3 PF13622.6 KXS94067.1 - 2.5e-09 37.8 0.2 2.8e-09 37.6 0.2 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Pyr_redox_2 PF07992.14 KXS94068.1 - 4e-16 59.1 0.0 5.9e-13 48.7 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KXS94068.1 - 4.9e-14 51.6 0.2 3e-12 45.8 0.0 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXS94068.1 - 1.5e-10 40.9 0.0 3.1e-10 39.8 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXS94068.1 - 1.5e-07 30.9 0.0 6.7e-07 28.8 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KXS94068.1 - 1.9e-07 31.2 0.4 4.8e-06 26.7 0.0 3.2 4 0 0 4 4 4 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXS94068.1 - 7.6e-05 22.5 0.1 0.0079 15.8 0.1 2.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXS94068.1 - 0.00071 18.8 0.0 0.0012 18.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KXS94068.1 - 0.091 12.1 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KXS94068.1 - 0.098 11.3 1.8 0.71 8.5 0.1 2.6 3 0 0 3 3 3 0 HI0933-like protein Thi4 PF01946.17 KXS94068.1 - 0.098 11.9 0.3 0.23 10.7 0.0 1.7 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.6 KXS94068.1 - 0.56 10.2 5.9 34 4.4 0.8 4.1 3 1 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KXS94069.1 - 2.4e-10 40.1 0.0 4.6e-07 29.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KXS94069.1 - 5.1e-10 38.4 0.1 4.3e-08 32.0 0.0 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KXS94069.1 - 9.4e-08 31.6 0.0 4.5e-07 29.3 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KXS94069.1 - 5.3e-07 29.2 0.0 1.2e-06 28.0 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXS94069.1 - 0.041 13.9 0.5 19 5.2 0.0 3.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KXS94070.1 - 8.9e-07 29.1 0.1 1.6e-06 28.2 0.1 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXS94070.1 - 9.4e-05 21.7 0.0 0.00012 21.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXS94070.1 - 0.00046 19.9 0.0 0.00065 19.4 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXS94070.1 - 0.0073 15.6 0.1 0.01 15.1 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXS94070.1 - 0.012 15.0 0.1 0.017 14.5 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 KXS94070.1 - 0.017 14.3 0.0 0.022 14.0 0.0 1.1 1 0 0 1 1 1 0 Thi4 family FMO-like PF00743.19 KXS94070.1 - 0.041 12.3 0.1 0.053 11.9 0.1 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like HI0933_like PF03486.14 KXS94070.1 - 0.056 12.1 0.1 0.073 11.8 0.1 1.1 1 0 0 1 1 1 0 HI0933-like protein 4HBT_3 PF13622.6 KXS94071.1 - 9.9e-12 45.6 0.0 1.1e-11 45.4 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Lactamase_B_3 PF13483.6 KXS94075.1 - 2.3e-05 24.3 0.5 9.6e-05 22.3 0.1 2.0 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 KXS94075.1 - 2.9e-05 23.7 0.4 0.00029 20.4 0.3 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain DUF1365 PF07103.11 KXS94076.1 - 2.5e-64 217.2 0.0 3.5e-64 216.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) SPRY PF00622.28 KXS94077.1 - 1.3e-05 25.3 1.0 2.4e-05 24.5 0.1 1.9 2 0 0 2 2 2 1 SPRY domain MARVEL PF01284.23 KXS94078.1 - 3.1e-22 79.2 15.5 3.9e-22 78.8 15.5 1.0 1 0 0 1 1 1 1 Membrane-associating domain Pro-kuma_activ PF09286.11 KXS94079.1 - 2.1e-36 125.3 0.0 3.3e-36 124.7 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KXS94079.1 - 6.3e-11 42.1 0.1 1.2e-10 41.1 0.1 1.4 1 0 0 1 1 1 1 Subtilase family HATPase_c PF02518.26 KXS94080.1 - 1e-21 77.5 0.0 2.1e-21 76.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXS94080.1 - 1.4e-15 57.4 0.2 2.8e-15 56.5 0.2 1.5 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.7 KXS94080.1 - 3.6e-07 30.4 0.0 2e-06 28.0 0.0 2.2 2 0 0 2 2 2 1 PAS domain HisKA PF00512.25 KXS94080.1 - 3.6e-06 26.9 2.3 7.5e-06 25.9 0.1 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 KXS94080.1 - 4.2e-05 23.9 0.0 0.00031 21.0 0.0 2.4 2 0 0 2 2 2 1 GAF domain PAS PF00989.25 KXS94080.1 - 0.00014 21.9 0.0 0.0048 16.9 0.0 2.6 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 KXS94080.1 - 0.00044 20.5 0.0 0.02 15.1 0.0 2.6 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 KXS94080.1 - 0.0054 17.0 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 KXS94080.1 - 0.0064 16.5 0.0 0.018 15.0 0.0 1.8 1 0 0 1 1 1 1 PAS domain GAF_3 PF13492.6 KXS94080.1 - 0.075 13.4 0.0 0.21 11.9 0.0 1.8 1 0 0 1 1 1 0 GAF domain PhoD PF09423.10 KXS94081.1 - 3.6e-44 151.2 0.0 1.2e-43 149.5 0.0 2.0 1 1 0 1 1 1 1 PhoD-like phosphatase Pur_ac_phosph_N PF16656.5 KXS94081.1 - 0.016 15.8 0.0 0.039 14.5 0.0 1.6 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain CarboxypepD_reg PF13620.6 KXS94081.1 - 0.1 12.9 0.4 0.23 11.7 0.4 1.6 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain GGACT PF06094.12 KXS94085.1 - 1.4e-05 25.7 1.0 2e-05 25.2 0.9 1.3 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Peptidase_C48 PF02902.19 KXS94086.1 - 2.2e-28 99.6 0.0 4.2e-28 98.7 0.0 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain bZIP_1 PF00170.21 KXS94087.1 - 0.016 15.3 12.5 0.14 12.3 5.0 3.0 1 1 2 3 3 3 0 bZIP transcription factor bZIP_Maf PF03131.17 KXS94087.1 - 0.13 12.7 16.2 0.035 14.6 11.8 2.3 1 1 1 2 2 2 0 bZIP Maf transcription factor DUF4686 PF15742.5 KXS94087.1 - 0.47 9.5 13.7 0.74 8.9 13.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) DUF5383 PF17355.2 KXS94087.1 - 0.49 10.8 2.8 1.2 9.5 2.8 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5383) bZIP_2 PF07716.15 KXS94087.1 - 5.9 7.0 23.9 0.033 14.3 6.3 3.6 2 1 2 4 4 4 0 Basic region leucine zipper PQ-loop PF04193.14 KXS94088.1 - 7.2e-20 70.5 1.0 3.8e-12 45.8 0.1 2.4 2 0 0 2 2 2 2 PQ loop repeat PQ-loop PF04193.14 KXS94089.1 - 7.3e-20 70.5 1.0 3.9e-12 45.7 0.1 2.4 2 0 0 2 2 2 2 PQ loop repeat PQ-loop PF04193.14 KXS94090.1 - 7.2e-20 70.5 1.0 3.8e-12 45.8 0.1 2.4 2 0 0 2 2 2 2 PQ loop repeat MFS_1 PF07690.16 KXS94091.1 - 2.2e-12 46.6 17.6 1.3e-11 44.0 17.8 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS94091.1 - 1.2e-07 31.0 6.7 1.7e-05 23.9 6.7 2.9 1 1 0 1 1 1 1 Sugar (and other) transporter DUF1682 PF07946.14 KXS94091.1 - 0.12 11.6 2.5 0.17 11.1 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) S_4TM PF18159.1 KXS94091.1 - 0.14 11.5 0.0 0.14 11.5 0.0 3.8 4 0 0 4 4 4 0 SMODS-associating 4TM effector domain IF4E PF01652.18 KXS94092.1 - 6.4e-57 191.8 0.4 9.8e-57 191.2 0.1 1.5 2 0 0 2 2 2 1 Eukaryotic initiation factor 4E Fungal_trans PF04082.18 KXS94093.1 - 2.3e-10 40.0 0.0 4.1e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PPDFL PF15060.6 KXS94093.1 - 0.0035 17.9 0.3 1.1 9.8 0.0 2.6 2 0 0 2 2 2 2 Differentiation and proliferation regulator Spc7_C2 PF15577.6 KXS94093.1 - 0.14 12.2 0.1 0.3 11.2 0.1 1.5 1 0 0 1 1 1 0 Spc7_C2 HET PF06985.11 KXS94094.1 - 2.9e-14 53.6 0.8 5.9e-14 52.6 0.1 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Aldedh PF00171.22 KXS94103.1 - 6.5e-29 100.7 0.5 8.3e-29 100.4 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1542 PF07564.11 KXS94103.1 - 0.032 14.3 0.2 0.096 12.8 0.1 1.9 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1542) Pyr_redox_2 PF07992.14 KXS94104.1 - 4.5e-22 78.6 0.1 1.2e-21 77.2 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXS94104.1 - 5.5e-12 46.1 1.5 2.5e-11 44.0 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXS94104.1 - 0.0011 18.2 0.3 0.0024 17.1 0.3 1.5 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.24 KXS94104.1 - 0.0026 17.1 0.1 0.0052 16.1 0.0 1.5 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 KXS94104.1 - 0.0027 16.8 0.5 0.0076 15.3 0.4 1.7 1 1 1 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KXS94104.1 - 0.017 14.4 1.4 0.21 10.8 0.4 2.1 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXS94104.1 - 0.018 14.2 0.0 2.4 7.1 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KXS94104.1 - 0.056 13.4 0.4 3.9 7.5 0.0 3.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KXS94105.1 - 4.5e-22 78.6 0.1 1.2e-21 77.2 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXS94105.1 - 5.5e-12 46.1 1.5 2.5e-11 44.0 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXS94105.1 - 0.0011 18.2 0.3 0.0024 17.1 0.3 1.5 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.24 KXS94105.1 - 0.0026 17.1 0.1 0.0052 16.1 0.0 1.5 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 KXS94105.1 - 0.0027 16.8 0.5 0.0076 15.3 0.4 1.7 1 1 1 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KXS94105.1 - 0.017 14.4 1.4 0.21 10.8 0.4 2.1 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXS94105.1 - 0.018 14.2 0.0 2.4 7.1 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KXS94105.1 - 0.056 13.4 0.4 3.9 7.5 0.0 3.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding Fungal_trans PF04082.18 KXS94106.1 - 1.6e-29 102.7 0.0 2.6e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS94106.1 - 4.8e-09 36.2 9.0 8.5e-09 35.4 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tannase PF07519.11 KXS94108.1 - 1.1e-91 308.1 3.2 1.4e-91 307.8 3.2 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 KXS94108.1 - 0.0053 16.3 0.1 0.044 13.2 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Tmemb_14 PF03647.13 KXS94108.1 - 0.24 12.2 1.2 7.6 7.4 0.5 2.3 2 0 0 2 2 2 0 Transmembrane proteins 14C PP2C PF00481.21 KXS94109.1 - 6.5e-36 124.3 0.0 1.3e-35 123.3 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C Lac_bphage_repr PF06543.12 KXS94109.1 - 0.029 14.4 0.3 0.09 12.8 0.1 1.9 2 0 0 2 2 2 0 Lactococcus bacteriophage repressor SpoIIE PF07228.12 KXS94109.1 - 0.037 13.9 0.1 7.5 6.4 0.0 3.2 2 2 1 3 3 3 0 Stage II sporulation protein E (SpoIIE) DBP10CT PF08147.12 KXS94109.1 - 0.15 12.3 0.2 7.2 6.9 0.1 2.4 2 0 0 2 2 2 0 DBP10CT (NUC160) domain Fanconi_A_N PF15865.5 KXS94110.1 - 0.1 12.0 0.1 0.12 11.7 0.1 1.1 1 0 0 1 1 1 0 Fanconi anaemia group A protein N terminus Blt1 PF12754.7 KXS94111.1 - 1.8 8.8 4.6 2.9 8.2 3.7 1.9 1 1 0 1 1 1 0 Blt1 N-terminal domain Aldedh PF00171.22 KXS94113.1 - 2e-136 455.2 0.3 2.2e-136 455.0 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LicD PF04991.13 KXS94114.1 - 1.6e-18 67.7 5.0 9.9e-14 52.0 2.4 2.1 1 1 1 2 2 2 2 LicD family Glyco_hydro_53 PF07745.13 KXS94116.1 - 2.3e-66 224.1 0.0 2.7e-66 223.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Cellulase PF00150.18 KXS94116.1 - 0.00014 21.4 0.1 0.00031 20.3 0.0 1.6 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_53 PF07745.13 KXS94117.1 - 1e-19 70.7 0.1 1.3e-19 70.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Cellulase PF00150.18 KXS94117.1 - 7.7e-05 22.2 0.0 9e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Aldose_epim PF01263.20 KXS94118.1 - 7.9e-49 166.6 0.2 9.5e-49 166.3 0.2 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Amidase PF01425.21 KXS94119.1 - 6.8e-91 305.5 0.0 8.5e-91 305.2 0.0 1.1 1 0 0 1 1 1 1 Amidase TFR_dimer PF04253.15 KXS94123.1 - 1e-29 103.1 0.0 1.8e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KXS94123.1 - 1.7e-20 73.6 0.0 4.1e-20 72.3 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.22 KXS94123.1 - 5.2e-10 39.2 0.3 2e-09 37.3 0.0 2.0 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 KXS94123.1 - 0.00092 19.0 0.0 0.0022 17.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 KXS94123.1 - 0.0029 17.1 0.0 0.006 16.1 0.0 1.4 1 0 0 1 1 1 1 Nicastrin DUF1494 PF07379.11 KXS94123.1 - 0.071 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1494) TFR_dimer PF04253.15 KXS94124.1 - 1e-29 103.1 0.0 1.8e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KXS94124.1 - 1.7e-20 73.6 0.0 4.1e-20 72.3 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.22 KXS94124.1 - 5.2e-10 39.2 0.3 2e-09 37.3 0.0 2.0 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 KXS94124.1 - 0.00092 19.0 0.0 0.0022 17.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 KXS94124.1 - 0.0029 17.1 0.0 0.006 16.1 0.0 1.4 1 0 0 1 1 1 1 Nicastrin DUF1494 PF07379.11 KXS94124.1 - 0.071 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1494) TFR_dimer PF04253.15 KXS94125.1 - 1e-29 103.1 0.0 1.8e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KXS94125.1 - 1.7e-20 73.6 0.0 4.1e-20 72.3 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.22 KXS94125.1 - 5.2e-10 39.2 0.3 2e-09 37.3 0.0 2.0 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 KXS94125.1 - 0.00092 19.0 0.0 0.0022 17.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 KXS94125.1 - 0.0029 17.1 0.0 0.006 16.1 0.0 1.4 1 0 0 1 1 1 1 Nicastrin DUF1494 PF07379.11 KXS94125.1 - 0.071 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1494) p450 PF00067.22 KXS94126.1 - 1.6e-34 119.4 0.0 2.1e-34 119.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 ApbA_C PF08546.11 KXS94126.1 - 0.091 13.0 0.1 0.17 12.1 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal DUF3605 PF12239.8 KXS94127.1 - 1.7e-54 184.3 0.0 2.3e-54 183.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Transp_cyt_pur PF02133.15 KXS94128.1 - 2.2e-40 138.8 40.5 2.7e-40 138.5 40.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin 4F5 PF04419.14 KXS94129.1 - 7.6 7.5 10.4 0.21 12.5 2.4 2.6 2 0 0 2 2 2 0 4F5 protein family HMG-CoA_red PF00368.18 KXS94130.1 - 1.6e-141 471.6 4.3 2e-141 471.2 4.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.6 KXS94130.1 - 2.3e-40 138.0 0.1 3.9e-40 137.3 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.8 KXS94130.1 - 6.4e-15 55.3 2.7 1.4e-14 54.2 2.7 1.6 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KXS94130.1 - 5.7e-08 31.3 3.3 5.7e-08 31.3 3.3 1.4 2 0 0 2 2 2 1 Patched family GIT_SHD PF08518.11 KXS94131.1 - 9.6e-23 79.5 8.1 5.8e-12 45.0 1.5 2.5 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT SOGA PF11365.8 KXS94131.1 - 0.26 12.4 0.2 0.26 12.4 0.2 4.1 2 1 1 3 3 3 0 Protein SOGA GAS PF13851.6 KXS94131.1 - 0.33 10.3 54.9 0.015 14.7 20.2 3.4 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding MscS_porin PF12795.7 KXS94131.1 - 1.5 8.3 50.5 3.7 7.0 50.3 1.8 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain ADIP PF11559.8 KXS94131.1 - 1.9 8.5 54.6 1.3 9.1 17.0 4.3 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding MAD PF05557.13 KXS94131.1 - 2 6.7 48.3 2.9 6.1 48.3 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein DUF4172 PF13776.6 KXS94131.1 - 7.7 6.9 8.8 0.87 10.0 2.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4172) Pribosyltran_N PF13793.6 KXS94132.1 - 3.3e-38 130.2 0.9 5.5e-36 123.0 0.2 3.2 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KXS94132.1 - 1.2e-34 119.9 0.6 2.2e-29 102.8 0.0 2.6 3 0 0 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KXS94132.1 - 1.7e-08 34.2 0.1 3.7e-05 23.3 0.1 3.2 3 0 0 3 3 3 2 Phosphoribosyl transferase domain Kre28 PF17097.5 KXS94133.1 - 2.5e-06 26.7 5.6 3.2e-06 26.3 5.6 1.1 1 0 0 1 1 1 1 Spindle pole body component Spc7 PF08317.11 KXS94133.1 - 0.00015 20.8 17.2 0.016 14.1 3.6 2.1 2 0 0 2 2 2 2 Spc7 kinetochore protein UPF0242 PF06785.11 KXS94133.1 - 0.012 15.8 21.4 0.023 14.8 6.5 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus AAA_13 PF13166.6 KXS94133.1 - 0.019 13.6 4.7 0.024 13.3 4.7 1.2 1 0 0 1 1 1 0 AAA domain NPV_P10 PF05531.12 KXS94133.1 - 0.021 15.3 4.1 0.62 10.6 0.2 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein TMF_TATA_bd PF12325.8 KXS94133.1 - 0.021 15.0 18.8 0.26 11.5 1.2 3.4 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding BRE1 PF08647.11 KXS94133.1 - 0.024 14.7 3.2 0.024 14.7 3.2 3.0 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase Het-C PF07217.11 KXS94133.1 - 0.11 11.0 1.3 0.16 10.5 1.3 1.2 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C DUF641 PF04859.12 KXS94133.1 - 0.15 12.4 14.0 0.18 12.1 4.6 2.9 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) FlaC_arch PF05377.11 KXS94133.1 - 0.18 12.2 8.7 4.9 7.6 0.4 3.7 3 1 1 4 4 3 0 Flagella accessory protein C (FlaC) BLOC1_2 PF10046.9 KXS94133.1 - 0.2 12.0 8.2 0.09 13.1 2.9 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FUSC PF04632.12 KXS94133.1 - 0.2 10.1 9.6 0.3 9.6 9.6 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4407 PF14362.6 KXS94133.1 - 0.31 10.4 10.7 0.42 9.9 10.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 KXS94133.1 - 0.41 9.7 15.0 0.49 9.4 5.6 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fib_alpha PF08702.10 KXS94133.1 - 0.61 10.3 5.3 1.8 8.7 4.6 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 KXS94133.1 - 0.78 9.8 7.6 1.3 9.1 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) GvpK PF05121.12 KXS94133.1 - 1.1 9.4 13.8 0.19 11.8 2.3 3.3 2 1 1 3 3 3 0 Gas vesicle protein K Prefoldin PF02996.17 KXS94133.1 - 1.3 9.0 11.7 3.5 7.6 1.8 3.4 1 1 2 3 3 3 0 Prefoldin subunit BST2 PF16716.5 KXS94133.1 - 1.6 9.3 16.8 7.1 7.3 3.3 3.7 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 Exonuc_VII_L PF02601.15 KXS94133.1 - 1.7 8.2 12.4 11 5.5 12.4 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit Fez1 PF06818.15 KXS94133.1 - 2.9 8.3 20.0 48 4.3 19.9 2.5 1 1 0 1 1 1 0 Fez1 COG2 PF06148.11 KXS94133.1 - 4 7.5 10.3 4.7 7.3 1.3 2.6 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Syntaxin-6_N PF09177.11 KXS94133.1 - 5 7.7 9.4 1.5 9.5 1.8 2.7 2 2 0 2 2 2 0 Syntaxin 6, N-terminal APG6_N PF17675.1 KXS94133.1 - 5.1 7.6 25.0 1.1 9.8 11.1 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region HIP1_clath_bdg PF16515.5 KXS94133.1 - 5.4 7.7 20.1 1.2 9.8 5.3 3.2 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF5344 PF17279.2 KXS94133.1 - 6.1 7.5 8.2 6.1 7.5 0.1 3.5 3 1 0 3 3 3 0 Family of unknown function (DUF5344) GAS PF13851.6 KXS94133.1 - 8.4 5.7 20.8 4.4 6.6 4.7 2.5 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding OmpH PF03938.14 KXS94133.1 - 9.9 6.5 26.2 8.1 6.8 11.0 2.5 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) Kre28 PF17097.5 KXS94134.1 - 2.5e-06 26.7 5.6 3.2e-06 26.3 5.6 1.1 1 0 0 1 1 1 1 Spindle pole body component Spc7 PF08317.11 KXS94134.1 - 0.00015 20.8 17.2 0.016 14.1 3.6 2.1 2 0 0 2 2 2 2 Spc7 kinetochore protein UPF0242 PF06785.11 KXS94134.1 - 0.012 15.8 21.4 0.023 14.8 6.5 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus AAA_13 PF13166.6 KXS94134.1 - 0.019 13.6 4.7 0.024 13.3 4.7 1.2 1 0 0 1 1 1 0 AAA domain NPV_P10 PF05531.12 KXS94134.1 - 0.021 15.3 4.1 0.62 10.6 0.2 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein TMF_TATA_bd PF12325.8 KXS94134.1 - 0.021 15.0 18.8 0.26 11.5 1.2 3.4 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding BRE1 PF08647.11 KXS94134.1 - 0.024 14.7 3.2 0.024 14.7 3.2 3.0 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase Het-C PF07217.11 KXS94134.1 - 0.11 11.0 1.3 0.16 10.5 1.3 1.2 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C DUF641 PF04859.12 KXS94134.1 - 0.15 12.4 14.0 0.18 12.1 4.6 2.9 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) FlaC_arch PF05377.11 KXS94134.1 - 0.18 12.2 8.7 4.9 7.6 0.4 3.7 3 1 1 4 4 3 0 Flagella accessory protein C (FlaC) BLOC1_2 PF10046.9 KXS94134.1 - 0.2 12.0 8.2 0.09 13.1 2.9 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FUSC PF04632.12 KXS94134.1 - 0.2 10.1 9.6 0.3 9.6 9.6 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4407 PF14362.6 KXS94134.1 - 0.31 10.4 10.7 0.42 9.9 10.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 KXS94134.1 - 0.41 9.7 15.0 0.49 9.4 5.6 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fib_alpha PF08702.10 KXS94134.1 - 0.61 10.3 5.3 1.8 8.7 4.6 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 KXS94134.1 - 0.78 9.8 7.6 1.3 9.1 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) GvpK PF05121.12 KXS94134.1 - 1.1 9.4 13.8 0.19 11.8 2.3 3.3 2 1 1 3 3 3 0 Gas vesicle protein K Prefoldin PF02996.17 KXS94134.1 - 1.3 9.0 11.7 3.5 7.6 1.8 3.4 1 1 2 3 3 3 0 Prefoldin subunit BST2 PF16716.5 KXS94134.1 - 1.6 9.3 16.8 7.1 7.3 3.3 3.7 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 Exonuc_VII_L PF02601.15 KXS94134.1 - 1.7 8.2 12.4 11 5.5 12.4 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit Fez1 PF06818.15 KXS94134.1 - 2.9 8.3 20.0 48 4.3 19.9 2.5 1 1 0 1 1 1 0 Fez1 COG2 PF06148.11 KXS94134.1 - 4 7.5 10.3 4.7 7.3 1.3 2.6 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Syntaxin-6_N PF09177.11 KXS94134.1 - 5 7.7 9.4 1.5 9.5 1.8 2.7 2 2 0 2 2 2 0 Syntaxin 6, N-terminal APG6_N PF17675.1 KXS94134.1 - 5.1 7.6 25.0 1.1 9.8 11.1 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region HIP1_clath_bdg PF16515.5 KXS94134.1 - 5.4 7.7 20.1 1.2 9.8 5.3 3.2 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF5344 PF17279.2 KXS94134.1 - 6.1 7.5 8.2 6.1 7.5 0.1 3.5 3 1 0 3 3 3 0 Family of unknown function (DUF5344) GAS PF13851.6 KXS94134.1 - 8.4 5.7 20.8 4.4 6.6 4.7 2.5 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding OmpH PF03938.14 KXS94134.1 - 9.9 6.5 26.2 8.1 6.8 11.0 2.5 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) Bac_luciferase PF00296.20 KXS94135.1 - 1.1e-56 192.6 0.2 1.4e-56 192.2 0.2 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Pneumo_att_G PF05539.11 KXS94136.1 - 5.3 6.5 5.2 7.7 6.0 5.2 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Hid1 PF12722.7 KXS94136.1 - 6.9 4.7 5.9 8.1 4.4 5.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein UPF0121 PF03661.13 KXS94137.1 - 2.7e-30 105.5 2.2 3.4e-30 105.2 2.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) UcrQ PF02939.16 KXS94138.1 - 9e-27 92.8 0.1 1.1e-26 92.6 0.1 1.1 1 0 0 1 1 1 1 UcrQ family Yae1_N PF09811.9 KXS94139.1 - 1.9e-10 40.3 2.8 5.7e-10 38.7 2.8 1.9 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Amidohydro_2 PF04909.14 KXS94140.1 - 1.4e-38 133.3 0.1 1.8e-38 133.0 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase SdiA-regulated PF06977.11 KXS94140.1 - 0.12 11.5 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 SdiA-regulated Pectate_lyase PF03211.13 KXS94141.1 - 1.2e-74 250.3 6.3 1.4e-74 250.0 6.3 1.1 1 0 0 1 1 1 1 Pectate lyase AAA_12 PF13087.6 KXS94142.1 - 3.1e-20 72.6 0.0 5.6e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KXS94142.1 - 7.9e-05 22.6 0.1 0.00012 21.9 0.1 1.3 1 0 0 1 1 1 1 AAA domain PAN_1 PF00024.26 KXS94143.1 - 6e-09 35.7 15.1 0.017 15.1 0.0 4.8 5 0 0 5 5 5 3 PAN domain PAN_4 PF14295.6 KXS94143.1 - 3.2e-05 23.8 20.0 0.0066 16.3 0.3 5.3 5 0 0 5 5 5 3 PAN domain Metallophos PF00149.28 KXS94144.1 - 2.1e-12 48.0 1.1 3.3e-12 47.3 1.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXS94144.1 - 0.0005 20.3 0.3 0.0036 17.5 0.3 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain adh_short_C2 PF13561.6 KXS94145.1 - 5.9e-48 163.5 0.0 7.7e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS94145.1 - 8.4e-37 126.5 0.0 1.1e-36 126.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS94145.1 - 1.6e-08 34.7 0.1 2.4e-08 34.1 0.1 1.3 1 0 0 1 1 1 1 KR domain PGM_PMM_I PF02878.16 KXS94145.1 - 0.13 11.9 0.1 4.9 6.9 0.0 2.4 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I Dioxygenase_C PF00775.21 KXS94146.1 - 4e-38 130.7 0.0 5.6e-38 130.2 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KXS94146.1 - 8.3e-31 105.7 0.0 1.4e-30 104.9 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus DUF3294 PF07957.11 KXS94147.1 - 0.0027 17.5 0.0 0.0035 17.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3294) DUF3294 PF07957.11 KXS94148.1 - 0.0027 17.5 0.0 0.0035 17.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3294) DUF3445 PF11927.8 KXS94149.1 - 9.2e-73 244.6 0.0 1.3e-72 244.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) RCC1 PF00415.18 KXS94149.1 - 8e-51 170.5 3.5 1.5e-09 38.4 0.0 7.6 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KXS94149.1 - 1.2e-37 126.9 19.5 1e-09 37.9 0.2 6.5 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat Presenilin PF01080.17 KXS94149.1 - 9.2 4.9 6.5 13 4.4 6.5 1.2 1 0 0 1 1 1 0 Presenilin Cyclase PF04199.13 KXS94150.1 - 7.4e-10 39.2 0.0 1.8e-09 38.0 0.0 1.6 2 0 0 2 2 2 1 Putative cyclase Cupin_3 PF05899.12 KXS94150.1 - 3.7e-06 26.5 0.1 5.1e-05 22.9 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF861) EutQ PF06249.12 KXS94150.1 - 0.00063 19.5 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Ectoine_synth PF06339.12 KXS94150.1 - 0.12 12.5 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 Ectoine synthase DUF1295 PF06966.12 KXS94151.1 - 5.2e-07 29.4 0.0 9e-07 28.6 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) BTB PF00651.31 KXS94152.1 - 0.054 13.7 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 BTB/POZ domain Apolipoprotein PF01442.18 KXS94153.1 - 0.00038 20.4 16.1 0.099 12.5 7.2 3.3 1 1 0 2 2 2 2 Apolipoprotein A1/A4/E domain DnaI_N PF07319.11 KXS94153.1 - 0.0091 16.6 0.8 0.0091 16.6 0.8 2.8 3 1 0 3 3 3 1 Primosomal protein DnaI N-terminus DUF2939 PF11159.8 KXS94153.1 - 0.086 13.3 0.4 6.9 7.2 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF2939) Prominin PF05478.11 KXS94153.1 - 0.25 9.3 9.7 0.45 8.4 0.4 2.7 1 1 2 3 3 3 0 Prominin PheRS_DBD2 PF18554.1 KXS94153.1 - 0.37 10.8 9.0 8.8 6.4 0.1 5.1 5 0 0 5 5 5 0 PheRS DNA binding domain 2 FlgN PF05130.12 KXS94153.1 - 0.43 11.1 15.6 0.36 11.3 0.5 3.5 2 1 2 4 4 4 0 FlgN protein DDE_Tnp_ISL3 PF01610.17 KXS94153.1 - 1 9.0 6.6 0.94 9.1 4.0 2.3 1 1 1 2 2 2 0 Transposase Goodbye PF17109.5 KXS94153.1 - 1.5 9.3 6.3 7.5 7.0 0.1 4.0 3 1 0 4 4 4 0 fungal STAND N-terminal Goodbye domain DUF2937 PF11157.8 KXS94153.1 - 1.8 8.3 6.4 2.3 7.9 0.0 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF2937) DUF2408 PF10303.9 KXS94153.1 - 3.2 8.3 14.7 0.52 10.9 1.8 3.1 1 1 0 2 2 2 0 Protein of unknown function (DUF2408) XH PF03469.14 KXS94153.1 - 9.2 6.2 13.3 6.7 6.6 3.0 4.0 2 1 2 4 4 4 0 XH domain DUF4193 PF13834.6 KXS94154.1 - 0.083 13.4 0.1 0.22 12.0 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4193) F-box-like PF12937.7 KXS94157.1 - 0.002 18.0 0.0 0.0055 16.6 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KXS94158.1 - 0.002 18.0 0.0 0.0055 16.6 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KXS94159.1 - 0.002 18.0 0.0 0.0055 16.6 0.0 1.8 1 0 0 1 1 1 1 F-box-like FAD_binding_3 PF01494.19 KXS94160.1 - 3.6e-17 62.7 0.1 1.1e-16 61.0 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain Hist_deacetyl PF00850.19 KXS94160.1 - 0.00028 20.5 0.0 0.00046 19.8 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain DAO PF01266.24 KXS94160.1 - 0.00041 20.1 0.7 0.01 15.5 0.7 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXS94160.1 - 0.0017 18.6 0.2 0.0081 16.4 0.2 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXS94160.1 - 0.0078 15.3 0.3 0.013 14.7 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 KXS94160.1 - 0.0089 15.1 0.0 0.067 12.2 0.0 2.0 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_9 PF13454.6 KXS94160.1 - 0.23 11.5 0.6 1.8 8.5 0.6 2.4 1 1 0 1 1 1 0 FAD-NAD(P)-binding Hydrolase_like PF13242.6 KXS94161.1 - 1.1e-05 25.4 0.0 2.2e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 KXS94161.1 - 0.0016 18.5 0.0 0.0044 17.1 0.0 1.7 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Fungal_trans PF04082.18 KXS94162.1 - 1.5e-28 99.6 0.2 3e-28 98.6 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain cNMP_binding PF00027.29 KXS94162.1 - 1.8e-25 88.8 0.0 4.1e-16 58.8 0.0 5.1 5 0 0 5 5 5 3 Cyclic nucleotide-binding domain Patatin PF01734.22 KXS94162.1 - 1.7e-16 61.0 2.3 2.6e-11 44.1 1.4 2.7 2 0 0 2 2 2 2 Patatin-like phospholipase Zn_clus PF00172.18 KXS94162.1 - 0.0028 17.8 13.3 0.0055 16.8 13.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-RING_2 PF13639.6 KXS94170.1 - 5e-12 46.0 12.3 7.4e-12 45.4 12.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXS94170.1 - 1.3e-10 40.9 11.8 1.9e-10 40.4 11.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXS94170.1 - 6.1e-09 35.6 11.4 8.7e-09 35.1 11.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS94170.1 - 1.7e-08 34.2 13.5 2.4e-08 33.7 13.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXS94170.1 - 3e-08 33.6 9.8 5.6e-08 32.7 9.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 KXS94170.1 - 1.8e-07 31.3 6.8 3.8e-07 30.3 6.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KXS94170.1 - 5e-06 26.4 11.8 7.6e-06 25.8 11.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KXS94170.1 - 2.4e-05 24.1 13.2 0.00051 19.8 13.8 2.1 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KXS94170.1 - 0.00024 20.8 8.5 0.00072 19.3 8.6 1.7 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KXS94170.1 - 0.00026 21.1 11.3 0.00044 20.3 11.3 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 KXS94170.1 - 0.0038 17.3 7.2 0.0066 16.6 7.2 1.4 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-P11 PF03854.14 KXS94170.1 - 0.0065 16.1 10.6 0.12 12.1 11.0 2.2 1 1 1 2 2 2 1 P-11 zinc finger DUF1272 PF06906.11 KXS94170.1 - 0.011 15.9 10.7 0.03 14.4 10.7 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1272) zf-Nse PF11789.8 KXS94170.1 - 0.022 14.5 4.5 0.046 13.5 4.5 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 KXS94170.1 - 0.025 14.6 7.0 0.052 13.6 7.0 1.4 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 KXS94170.1 - 0.081 12.7 6.4 0.16 11.7 6.4 1.5 1 0 0 1 1 1 0 RING-like zinc finger FANCL_C PF11793.8 KXS94170.1 - 0.17 12.1 15.0 2.6 8.3 0.2 2.9 1 1 1 2 2 2 0 FANCL C-terminal domain GluR_Homer-bdg PF10606.9 KXS94170.1 - 0.33 11.2 1.8 2.9 8.1 0.1 2.3 1 1 1 2 2 2 0 Homer-binding domain of metabotropic glutamate receptor zinc-ribbons_6 PF07191.12 KXS94170.1 - 0.44 10.6 9.3 0.71 9.9 9.3 1.3 1 0 0 1 1 1 0 zinc-ribbons Tmpp129 PF10272.9 KXS94170.1 - 3.1 7.0 7.7 1.1 8.4 5.3 1.3 1 1 0 1 1 1 0 Putative transmembrane protein precursor DZR PF12773.7 KXS94170.1 - 3.9 7.6 10.3 5.1 7.2 8.9 1.7 1 1 0 1 1 1 0 Double zinc ribbon zf-C3H2C3 PF17122.5 KXS94170.1 - 4.4 7.4 8.7 9.7 6.3 8.7 1.6 1 0 0 1 1 1 0 Zinc-finger DUF2462 PF09495.10 KXS94171.1 - 1.5e-17 64.1 12.3 1.5e-17 64.1 12.3 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2462) DUF5102 PF17104.5 KXS94172.1 - 8.7e-93 311.5 0.2 1.6e-92 310.7 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5102) Clathrin_bdg PF15045.6 KXS94172.1 - 0.37 10.8 1.5 0.63 10.1 0.0 2.2 3 0 0 3 3 3 0 Clathrin-binding box of Aftiphilin, vesicle trafficking DUF5102 PF17104.5 KXS94173.1 - 8.7e-93 311.5 0.2 1.6e-92 310.7 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5102) Clathrin_bdg PF15045.6 KXS94173.1 - 0.37 10.8 1.5 0.63 10.1 0.0 2.2 3 0 0 3 3 3 0 Clathrin-binding box of Aftiphilin, vesicle trafficking TFIIA PF03153.13 KXS94174.1 - 9.7e-88 295.9 23.8 1.1e-87 295.7 23.8 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit FYDLN_acid PF09538.10 KXS94174.1 - 3.4 8.4 14.6 2.1 9.1 5.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) TFIIA PF03153.13 KXS94175.1 - 9.7e-88 295.9 23.8 1.1e-87 295.7 23.8 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit FYDLN_acid PF09538.10 KXS94175.1 - 3.4 8.4 14.6 2.1 9.1 5.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) TFIIA PF03153.13 KXS94176.1 - 9.7e-88 295.9 23.8 1.1e-87 295.7 23.8 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit FYDLN_acid PF09538.10 KXS94176.1 - 3.4 8.4 14.6 2.1 9.1 5.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Noc2 PF03715.13 KXS94177.1 - 1.4e-125 418.5 0.0 2.7e-125 417.5 0.0 1.5 1 0 0 1 1 1 1 Noc2p family Nop14 PF04147.12 KXS94177.1 - 0.0023 16.2 0.0 0.0023 16.2 0.0 3.4 2 2 1 3 3 3 1 Nop14-like family Glyco_hydro_115 PF15979.5 KXS94179.1 - 3.3e-139 464.1 0.8 3.3e-139 464.1 0.8 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 KXS94179.1 - 5.7e-57 192.3 0.4 1.5e-56 190.9 0.1 1.9 2 0 0 2 2 2 1 Gylcosyl hydrolase family 115 C-terminal domain Fer4_13 PF13370.6 KXS94180.1 - 0.97 10.0 5.5 3.3 8.3 0.2 3.8 3 2 0 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I Helo_like_N PF17111.5 KXS94180.1 - 1 8.7 3.3 4.7 6.5 0.0 2.6 2 1 0 2 2 2 0 Fungal N-terminal domain of STAND proteins Fer4_13 PF13370.6 KXS94181.1 - 0.97 10.0 5.5 3.3 8.3 0.2 3.8 3 2 0 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I Helo_like_N PF17111.5 KXS94181.1 - 1 8.7 3.3 4.7 6.5 0.0 2.6 2 1 0 2 2 2 0 Fungal N-terminal domain of STAND proteins Methyltransf_16 PF10294.9 KXS94184.1 - 2.8e-17 63.0 0.0 1.1e-16 61.0 0.0 2.0 2 0 0 2 2 2 1 Lysine methyltransferase DUF3426 PF11906.8 KXS94185.1 - 0.067 13.4 0.5 2.5 8.3 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3426) DUF3328 PF11807.8 KXS94187.1 - 1.8e-32 112.9 1.8 3.1e-32 112.1 1.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) RPE65 PF03055.15 KXS94188.1 - 7.4e-100 335.3 0.0 9.2e-100 335.0 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein TRM PF02005.16 KXS94189.1 - 4.8e-109 365.0 0.0 3.5e-94 316.0 0.0 2.1 1 1 1 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 KXS94189.1 - 7.3e-05 22.6 0.0 0.00016 21.5 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 KXS94189.1 - 0.1 12.2 0.0 0.3 10.6 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase small domain RNase_T PF00929.24 KXS94190.1 - 8.2e-17 62.2 0.0 1e-16 62.0 0.0 1.1 1 0 0 1 1 1 1 Exonuclease CheY-binding PF09078.11 KXS94190.1 - 0.07 13.3 0.7 0.89 9.7 0.1 2.2 2 0 0 2 2 2 0 CheY binding F-box PF00646.33 KXS94191.1 - 0.0038 17.1 0.1 0.0093 15.8 0.1 1.5 1 0 0 1 1 1 1 F-box domain Thiolase_N PF00108.23 KXS94193.1 - 5.8e-71 238.9 2.8 8.7e-71 238.3 2.8 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXS94193.1 - 4.6e-43 145.8 0.2 9.3e-43 144.8 0.2 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KXS94193.1 - 0.00015 21.5 0.5 0.00046 19.9 0.5 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain DUF3245 PF11595.8 KXS94194.1 - 6.5e-05 23.5 7.7 6.5e-05 23.5 7.7 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3245) RAC_head PF16717.5 KXS94195.1 - 1.2e-29 103.1 2.9 1.2e-29 103.1 2.9 3.5 4 1 0 4 4 4 1 Ribosome-associated complex head domain DnaJ PF00226.31 KXS94195.1 - 3.2e-19 68.8 1.0 1.1e-18 67.0 1.0 2.0 1 0 0 1 1 1 1 DnaJ domain TrmO_C PF18389.1 KXS94195.1 - 0.00015 21.8 0.6 0.00039 20.5 0.6 1.7 1 0 0 1 1 1 1 TrmO C-terminal domain F-box-like PF12937.7 KXS94196.1 - 0.00034 20.4 0.2 0.00034 20.4 0.2 2.0 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KXS94196.1 - 0.009 15.9 0.2 0.023 14.6 0.0 1.7 2 0 0 2 2 2 1 F-box domain SGL PF08450.12 KXS94197.1 - 2.4e-20 73.1 0.6 9.1e-20 71.3 0.6 1.8 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 KXS94197.1 - 2.2e-07 30.9 0.0 7.3e-06 26.0 0.0 2.5 2 0 0 2 2 2 1 Strictosidine synthase Arylesterase PF01731.20 KXS94197.1 - 0.0054 16.9 0.1 0.02 15.1 0.0 2.0 2 0 0 2 2 2 1 Arylesterase NHL PF01436.21 KXS94197.1 - 0.019 15.0 0.0 0.11 12.6 0.0 2.4 1 0 0 1 1 1 0 NHL repeat Sugar_tr PF00083.24 KXS94198.1 - 8.6e-75 252.3 21.0 1.1e-74 252.0 21.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS94198.1 - 1e-23 83.9 46.9 2.2e-22 79.5 26.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PCI PF01399.27 KXS94199.1 - 9.5e-10 38.9 0.4 2.1e-09 37.8 0.4 1.6 1 0 0 1 1 1 1 PCI domain Rpn9_C PF18261.1 KXS94199.1 - 0.011 15.3 0.1 0.021 14.4 0.1 1.5 1 0 0 1 1 1 0 Rpn9 C-terminal helix Frag1 PF10277.9 KXS94200.1 - 5.5e-36 124.2 10.9 5.5e-36 124.2 10.9 2.9 2 1 0 2 2 2 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.23 KXS94200.1 - 0.022 14.3 0.0 0.067 12.7 0.0 1.8 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Frag1 PF10277.9 KXS94202.1 - 5.3e-36 124.2 10.9 5.3e-36 124.2 10.9 2.9 2 1 0 2 2 2 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.23 KXS94202.1 - 0.022 14.3 0.0 0.066 12.7 0.0 1.8 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family DUF1479 PF07350.12 KXS94204.1 - 4.2e-123 411.2 0.0 4.8e-123 411.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) U3_assoc_6 PF08640.11 KXS94205.1 - 1.2e-27 95.7 1.0 2.4e-25 88.4 0.1 2.4 2 0 0 2 2 2 2 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 KXS94205.1 - 0.0002 21.9 5.7 0.055 14.3 0.0 5.2 5 1 2 7 7 7 2 Tetratricopeptide repeat NRDE-2 PF08424.10 KXS94205.1 - 0.00036 19.8 0.3 0.0079 15.4 0.0 2.6 2 1 1 3 3 3 1 NRDE-2, necessary for RNA interference Phage_lysis PF03245.13 KXS94205.1 - 0.056 13.6 0.1 1.7 8.8 0.2 2.5 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein NmrA PF05368.13 KXS94206.1 - 6.9e-15 55.2 0.0 1e-14 54.7 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KXS94206.1 - 3.9e-14 52.7 0.0 9.3e-14 51.5 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXS94206.1 - 2.4e-12 46.4 0.0 1.5e-11 43.9 0.0 1.9 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KXS94206.1 - 3.9e-12 46.4 0.0 1.4e-11 44.7 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KXS94206.1 - 4.2e-06 26.1 0.0 9.4e-05 21.6 0.0 2.5 1 1 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KXS94206.1 - 4.6e-06 26.3 0.0 8.1e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KXS94206.1 - 6.3e-05 22.3 0.1 0.057 12.6 0.1 2.8 1 1 1 2 2 2 2 Male sterility protein adh_short PF00106.25 KXS94206.1 - 0.0011 18.5 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS94206.1 - 0.02 14.8 0.0 0.56 10.1 0.0 2.4 2 0 0 2 2 2 0 KR domain Polysacc_synt_2 PF02719.15 KXS94206.1 - 0.17 11.0 0.0 0.31 10.1 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein APH PF01636.23 KXS94215.1 - 0.00039 20.4 0.0 0.12 12.2 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family adh_short_C2 PF13561.6 KXS94216.1 - 5.1e-46 157.1 0.0 6.3e-46 156.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS94216.1 - 1.3e-34 119.4 0.0 1.6e-34 119.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS94216.1 - 8.8e-08 32.3 0.0 1.3e-07 31.7 0.0 1.3 1 1 0 1 1 1 1 KR domain Yip1 PF04893.17 KXS94217.1 - 4e-14 52.7 13.1 6.1e-14 52.1 13.1 1.3 1 1 0 1 1 1 1 Yip1 domain DUF1282 PF06930.12 KXS94217.1 - 0.0038 17.0 3.3 0.0069 16.2 3.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) HET PF06985.11 KXS94218.1 - 8e-28 97.6 2.7 1.5e-27 96.7 2.7 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Aa_trans PF01490.18 KXS94219.1 - 1.6e-14 53.5 30.5 5.4e-14 51.7 30.5 1.7 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein HET PF06985.11 KXS94220.1 - 8e-28 97.6 2.7 1.5e-27 96.7 2.7 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_M36 PF02128.15 KXS94221.1 - 9.6e-154 512.0 0.1 1.3e-153 511.6 0.1 1.2 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 KXS94221.1 - 4.7e-16 58.3 3.4 7.2e-16 57.8 2.4 1.9 2 0 0 2 2 2 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.15 KXS94221.1 - 0.0022 17.9 0.0 0.0045 16.9 0.0 1.5 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Lipoprotein_X PF03305.13 KXS94221.1 - 0.0075 16.0 0.2 0.014 15.2 0.2 1.3 1 0 0 1 1 1 1 Mycoplasma MG185/MG260 protein Peptidase_M36 PF02128.15 KXS94222.1 - 8.6e-154 512.2 0.1 1.1e-153 511.8 0.1 1.2 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 KXS94222.1 - 4.4e-16 58.5 3.4 6.8e-16 57.8 2.4 1.9 2 0 0 2 2 2 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.15 KXS94222.1 - 0.002 18.0 0.0 0.0041 17.0 0.0 1.5 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Lipoprotein_X PF03305.13 KXS94222.1 - 0.0071 16.1 0.2 0.013 15.3 0.2 1.3 1 0 0 1 1 1 1 Mycoplasma MG185/MG260 protein Epimerase PF01370.21 KXS94225.1 - 1e-08 35.0 1.1 7.9e-08 32.1 1.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KXS94225.1 - 6.9e-06 25.8 0.7 1e-05 25.3 0.7 1.3 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 KXS94225.1 - 1.2e-05 25.5 0.9 2.4e-05 24.6 0.5 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 KXS94225.1 - 0.00025 20.6 0.2 0.00047 19.6 0.2 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KXS94225.1 - 0.00045 19.4 0.3 0.0016 17.6 0.4 1.9 2 1 0 2 2 2 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KXS94225.1 - 0.0079 15.2 0.4 0.024 13.7 0.3 1.8 3 0 0 3 3 3 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 KXS94225.1 - 0.15 12.0 2.1 0.21 11.5 1.3 1.6 1 1 1 2 2 2 0 KR domain TrkA_N PF02254.18 KXS94225.1 - 0.18 12.1 1.7 0.2 11.9 0.3 1.9 3 0 0 3 3 3 0 TrkA-N domain peroxidase PF00141.23 KXS94226.1 - 1e-79 267.4 0.0 9e-41 140.1 0.0 2.3 2 0 0 2 2 2 2 Peroxidase DUF3519 PF12033.8 KXS94227.1 - 5 7.6 10.5 3.8 7.9 3.9 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3519) LTXXQ PF07813.12 KXS94227.1 - 9.1 7.1 10.9 4.1 8.2 0.6 4.0 4 0 0 4 4 4 0 LTXXQ motif family protein UPF0258 PF06789.12 KXS94229.1 - 0.087 13.0 0.0 0.12 12.5 0.0 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0258) AAA_13 PF13166.6 KXS94235.1 - 0.091 11.4 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain His_Phos_1 PF00300.22 KXS94236.1 - 8.6e-17 61.5 0.0 1.3e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) OTT_1508_deam PF14441.6 KXS94237.1 - 1.8e-16 59.9 1.7 4.8e-16 58.5 1.7 1.8 1 0 0 1 1 1 1 OTT_1508-like deaminase DnaI_N PF07319.11 KXS94237.1 - 0.16 12.7 0.3 0.31 11.7 0.3 1.5 1 0 0 1 1 1 0 Primosomal protein DnaI N-terminus dsrm PF00035.26 KXS94239.1 - 0.00041 21.0 2.1 0.0014 19.3 1.0 2.5 3 1 0 3 3 3 1 Double-stranded RNA binding motif DUF4071 PF13281.6 KXS94239.1 - 0.099 11.7 1.2 3.8 6.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4071) Transcrip_reg PF01709.20 KXS94241.1 - 0.029 13.8 0.5 0.037 13.5 0.5 1.1 1 0 0 1 1 1 0 Transcriptional regulator Peptidase_S8_N PF16361.5 KXS94241.1 - 0.12 12.9 0.4 11 6.5 0.1 2.1 2 0 0 2 2 2 0 N-terminal of Subtilase family HicA_toxin PF07927.12 KXS94242.1 - 0.05 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 HicA toxin of bacterial toxin-antitoxin, Mit_KHE1 PF10173.9 KXS94242.1 - 0.064 13.3 0.0 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related DUF3220 PF11516.8 KXS94242.1 - 0.069 13.4 0.2 2 8.6 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3120) AA_permease_2 PF13520.6 KXS94243.1 - 1e-45 156.3 50.6 1.3e-45 156.0 50.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXS94243.1 - 6.9e-24 84.3 45.3 8.8e-24 83.9 45.3 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3593 PF12159.8 KXS94243.1 - 3 8.0 5.2 2.4 8.3 0.5 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3593) FAD_binding_4 PF01565.23 KXS94244.1 - 1.3e-28 99.4 8.0 2.4e-28 98.6 8.0 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXS94244.1 - 4.2e-09 36.4 1.4 9e-09 35.3 1.4 1.5 1 0 0 1 1 1 1 Berberine and berberine like AroM PF07302.11 KXS94244.1 - 0.07 12.5 0.2 0.3 10.5 0.1 2.0 3 0 0 3 3 3 0 AroM protein SDH_C PF18317.1 KXS94244.1 - 0.13 12.1 0.3 0.62 9.9 0.1 2.1 2 0 0 2 2 2 0 Shikimate 5'-dehydrogenase C-terminal domain ChAPs PF09295.10 KXS94246.1 - 5.1e-146 486.7 0.0 6.4e-146 486.4 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_2 PF07719.17 KXS94246.1 - 2.7e-05 23.9 0.8 0.083 13.0 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXS94246.1 - 0.00028 21.3 2.1 0.041 14.4 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXS94246.1 - 0.0017 19.0 4.9 5.8 8.0 0.1 5.2 2 2 3 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 KXS94246.1 - 0.002 17.4 0.7 1 8.5 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXS94246.1 - 0.079 12.8 0.1 35 4.5 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Ank_2 PF12796.7 KXS94247.1 - 3.7e-20 72.3 0.2 0.00016 22.2 0.0 4.2 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS94247.1 - 4.1e-15 54.4 1.4 0.058 14.0 0.1 6.4 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 KXS94247.1 - 2e-13 50.6 0.3 0.0038 17.8 0.0 5.4 3 1 3 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS94247.1 - 9.7e-10 38.5 6.2 0.051 13.9 0.2 5.4 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 KXS94247.1 - 1.6e-09 37.7 6.1 0.00083 19.7 0.7 5.5 6 0 0 6 6 6 3 Ankyrin repeat MFS_1 PF07690.16 KXS94248.1 - 4.2e-28 98.3 26.7 2.5e-27 95.7 24.4 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-RING_2 PF13639.6 KXS94259.1 - 1.6e-07 31.5 8.8 1.6e-07 31.5 8.8 2.1 2 0 0 2 2 2 1 Ring finger domain Prok-RING_1 PF14446.6 KXS94259.1 - 2.7e-05 24.0 6.2 0.0057 16.6 3.6 2.6 2 0 0 2 2 2 2 Prokaryotic RING finger family 1 zf-ANAPC11 PF12861.7 KXS94259.1 - 0.0013 18.8 2.4 0.0013 18.8 2.4 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KXS94259.1 - 0.016 15.0 10.0 0.016 15.0 10.0 1.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF883 PF05957.13 KXS94259.1 - 0.019 15.5 1.4 0.027 15.0 0.2 1.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) zf-RING_5 PF14634.6 KXS94259.1 - 0.023 14.7 10.0 0.023 14.7 10.0 1.9 2 0 0 2 2 2 0 zinc-RING finger domain AC_N PF16214.5 KXS94259.1 - 0.066 12.3 0.4 0.09 11.9 0.4 1.2 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region RINGv PF12906.7 KXS94259.1 - 0.36 11.0 8.1 0.82 9.9 8.1 1.7 1 0 0 1 1 1 0 RING-variant domain zf-rbx1 PF12678.7 KXS94259.1 - 0.75 10.1 14.8 0.11 12.8 9.2 2.3 2 1 0 2 2 2 0 RING-H2 zinc finger domain FANCL_C PF11793.8 KXS94259.1 - 2.1 8.6 15.7 0.22 11.7 10.2 2.2 2 1 0 2 2 2 0 FANCL C-terminal domain TRI12 PF06609.13 KXS94260.1 - 1.3e-27 96.5 26.4 1.7e-27 96.2 26.4 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KXS94260.1 - 4.6e-16 58.7 60.3 4.6e-16 58.7 60.3 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Phage_holin_3_6 PF07332.11 KXS94260.1 - 0.019 15.0 2.5 0.019 15.0 2.5 5.7 2 2 4 6 6 6 0 Putative Actinobacterial Holin-X, holin superfamily III Shal-type PF11601.8 KXS94260.1 - 0.019 14.5 0.6 0.081 12.5 0.6 2.1 1 0 0 1 1 1 0 Shal-type voltage-gated potassium channels, N-terminal SET PF00856.28 KXS94265.1 - 3e-14 53.8 0.2 2.8e-13 50.6 0.0 2.5 2 1 0 2 2 2 1 SET domain PAM2 PF07145.15 KXS94265.1 - 0.17 11.7 3.7 0.18 11.6 1.6 2.2 1 1 1 2 2 2 0 Ataxin-2 C-terminal region RIO1 PF01163.22 KXS94266.1 - 1e-41 142.6 0.0 1.9e-41 141.7 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 KXS94266.1 - 5.8e-29 100.1 0.0 1.7e-28 98.7 0.0 1.8 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.23 KXS94266.1 - 1.2e-08 35.2 0.6 0.00023 21.2 0.2 3.0 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KXS94266.1 - 5.6e-07 29.1 0.1 3.4e-05 23.3 0.1 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KXS94267.1 - 1e-41 142.6 0.0 1.9e-41 141.7 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 KXS94267.1 - 5.8e-29 100.1 0.0 1.7e-28 98.7 0.0 1.8 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.23 KXS94267.1 - 1.2e-08 35.2 0.6 0.00023 21.2 0.2 3.0 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KXS94267.1 - 5.6e-07 29.1 0.1 3.4e-05 23.3 0.1 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family F-box-like PF12937.7 KXS94268.1 - 0.037 13.9 0.2 0.076 12.9 0.2 1.5 1 1 0 1 1 1 0 F-box-like MFS_1 PF07690.16 KXS94269.1 - 8.8e-36 123.6 24.4 1.2e-35 123.1 24.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1011 PF06237.12 KXS94269.1 - 0.049 14.0 0.9 0.21 11.9 0.9 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1011) Trp_oprn_chp PF09534.10 KXS94269.1 - 0.11 12.3 0.7 0.48 10.2 0.0 2.4 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Glyco_hydro_92 PF07971.12 KXS94270.1 - 1.1e-145 486.2 1.6 1.5e-145 485.7 1.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KXS94270.1 - 8.1e-58 196.1 1.5 1.3e-57 195.5 1.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain RPN1_RPN2_N PF17781.1 KXS94271.1 - 1.7e-118 395.6 2.7 3.1e-118 394.7 2.7 1.4 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 KXS94271.1 - 2.4e-29 101.2 0.0 4e-29 100.4 0.0 1.4 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 KXS94271.1 - 4.5e-17 61.5 15.8 1.9e-05 24.9 0.2 6.7 7 0 0 7 7 7 4 Proteasome/cyclosome repeat TPR_12 PF13424.6 KXS94271.1 - 0.035 14.4 0.6 0.51 10.7 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Ric8 PF10165.9 KXS94271.1 - 0.14 11.2 1.4 0.17 10.9 0.2 1.7 2 0 0 2 2 2 0 Guanine nucleotide exchange factor synembryn Fe-S_biosyn PF01521.20 KXS94281.1 - 1.4e-16 60.7 0.0 2.2e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis zf-RING_5 PF14634.6 KXS94282.1 - 0.00015 21.7 1.0 0.00029 20.7 1.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KXS94282.1 - 0.0016 18.8 1.9 0.0035 17.6 1.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KXS94282.1 - 0.021 14.9 2.5 0.043 13.9 2.5 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KXS94282.1 - 0.048 13.5 2.7 0.1 12.5 2.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS94282.1 - 0.092 12.6 2.5 0.23 11.4 2.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KXS94282.1 - 0.15 12.3 0.3 0.15 12.3 0.3 2.4 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING IBR PF01485.21 KXS94282.1 - 0.77 10.0 4.1 9 6.6 0.0 2.4 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain TIP49 PF06068.13 KXS94283.1 - 2e-162 540.3 0.0 2.6e-162 540.0 0.0 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KXS94283.1 - 3.4e-14 52.7 0.0 1.3e-13 50.9 0.0 2.0 2 0 0 2 2 1 1 TIP49 AAA-lid domain AAA PF00004.29 KXS94283.1 - 1.1e-11 45.3 0.1 3.5e-07 30.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KXS94283.1 - 3.1e-10 40.0 0.1 8.2e-07 28.9 0.0 2.3 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KXS94283.1 - 2e-05 24.9 0.1 0.37 11.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KXS94283.1 - 0.0011 19.4 0.8 0.0045 17.4 0.1 2.4 2 1 0 2 2 1 1 AAA ATPase domain AAA_5 PF07728.14 KXS94283.1 - 0.0011 18.9 0.3 0.17 11.9 0.1 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KXS94283.1 - 0.0013 18.5 0.0 1.8 8.2 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_28 PF13521.6 KXS94283.1 - 0.0015 18.8 0.1 0.003 17.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXS94283.1 - 0.0022 18.3 3.6 0.072 13.4 3.6 2.3 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KXS94283.1 - 0.0037 16.6 0.7 0.012 14.9 0.5 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_25 PF13481.6 KXS94283.1 - 0.0076 15.8 0.1 0.018 14.6 0.1 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KXS94283.1 - 0.012 15.0 0.1 0.6 9.4 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI PhoH PF02562.16 KXS94283.1 - 0.013 15.0 0.2 1.9 7.9 0.5 2.5 2 0 0 2 2 2 0 PhoH-like protein DUF2075 PF09848.9 KXS94283.1 - 0.022 14.0 0.0 0.035 13.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DnaB_C PF03796.15 KXS94283.1 - 0.042 13.2 0.0 0.086 12.2 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 KXS94283.1 - 0.059 13.1 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 KXS94283.1 - 0.099 12.1 0.2 0.31 10.5 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region T2SSE PF00437.20 KXS94283.1 - 0.12 11.5 0.1 0.53 9.3 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein ATPase PF06745.13 KXS94283.1 - 0.13 11.6 0.3 0.36 10.2 0.1 1.8 2 0 0 2 2 2 0 KaiC AAA_18 PF13238.6 KXS94283.1 - 0.15 12.6 0.0 0.41 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain PTR2 PF00854.21 KXS94284.1 - 1.1e-49 169.4 3.5 1.7e-49 168.7 3.5 1.3 1 0 0 1 1 1 1 POT family P5CR_dimer PF14748.6 KXS94285.1 - 1e-29 102.8 0.9 2.1e-29 101.8 0.9 1.6 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KXS94285.1 - 1.4e-10 41.6 3.4 1e-08 35.6 3.4 2.7 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent PDH PF02153.17 KXS94285.1 - 0.009 15.0 0.1 0.064 12.3 0.1 2.0 1 1 0 1 1 1 1 Prephenate dehydrogenase Ribosomal_L7Ae PF01248.26 KXS94287.1 - 1.5e-23 82.3 0.0 1.7e-23 82.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ist1 PF03398.14 KXS94288.1 - 3.8e-61 205.8 4.2 5e-61 205.4 4.2 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DUF2226 PF09987.9 KXS94288.1 - 0.31 10.4 3.2 0.93 8.8 0.2 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2226) SurE PF01975.17 KXS94289.1 - 3.5e-33 115.0 0.1 4.7e-33 114.6 0.1 1.1 1 0 0 1 1 1 1 Survival protein SurE PGM_PMM_I PF02878.16 KXS94290.1 - 1.5e-40 138.1 0.1 2.5e-40 137.4 0.1 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 KXS94290.1 - 5.4e-21 75.1 0.0 1.3e-20 74.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 KXS94290.1 - 1.5e-14 54.2 0.0 4e-14 52.8 0.0 1.7 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 KXS94290.1 - 5.6e-09 36.1 0.0 8.5e-08 32.3 0.0 2.6 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Cutinase PF01083.22 KXS94292.1 - 1.6e-30 106.4 0.5 1.6e-30 106.4 0.5 2.6 2 1 1 3 3 3 1 Cutinase Ribosomal_L16 PF00252.18 KXS94293.1 - 3.7e-45 153.2 0.1 5e-45 152.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Sugar_tr PF00083.24 KXS94294.1 - 4.2e-94 316.0 24.1 5.1e-94 315.7 24.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS94294.1 - 8.9e-22 77.5 16.3 8.9e-22 77.5 16.3 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF4378 PF14309.6 KXS94296.1 - 0.06 13.7 0.0 0.069 13.5 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4378) TPR_12 PF13424.6 KXS94298.1 - 5.1e-18 65.1 6.9 2.7e-09 37.2 0.3 3.8 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXS94298.1 - 6.8e-12 44.7 5.1 0.0059 16.4 0.5 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXS94298.1 - 2.1e-11 43.0 12.9 0.0074 16.3 0.0 5.7 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KXS94298.1 - 3.3e-09 36.6 0.5 3.3e-09 36.6 0.5 1.7 2 0 0 2 2 2 1 MalT-like TPR region DUF676 PF05057.14 KXS94298.1 - 2.1e-07 30.7 0.0 5e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) TPR_10 PF13374.6 KXS94298.1 - 2.8e-07 30.2 13.5 0.011 15.6 0.1 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat NB-ARC PF00931.22 KXS94298.1 - 8e-07 28.5 0.0 1.6e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_14 PF13428.6 KXS94298.1 - 2.9e-05 24.5 10.9 0.41 11.6 0.1 6.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXS94298.1 - 4.8e-05 23.9 17.9 0.023 15.3 0.3 4.7 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXS94298.1 - 9.6e-05 22.3 9.4 1.2 9.5 0.4 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXS94298.1 - 0.00014 22.3 0.2 0.65 10.5 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat Abhydrolase_6 PF12697.7 KXS94298.1 - 0.00093 19.9 0.0 0.0029 18.3 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family TPR_11 PF13414.6 KXS94298.1 - 0.0051 16.5 2.8 9.6 6.0 0.1 4.2 3 1 0 3 3 3 1 TPR repeat AAA_22 PF13401.6 KXS94298.1 - 0.036 14.3 0.0 0.17 12.1 0.0 2.1 1 0 0 1 1 1 0 AAA domain TPR_17 PF13431.6 KXS94298.1 - 0.065 13.6 2.1 0.16 12.4 0.4 2.6 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 KXS94298.1 - 0.093 13.4 3.7 0.82 10.5 0.0 3.9 4 0 0 4 4 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KXS94298.1 - 0.15 12.1 8.8 1.9 8.7 0.0 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat Zn_clus PF00172.18 KXS94299.1 - 4.9e-09 36.2 11.1 9.3e-09 35.3 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease_2 PF13520.6 KXS94302.1 - 1.3e-53 182.3 44.6 1.7e-53 182.0 44.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXS94302.1 - 1.2e-20 73.6 37.9 1.7e-20 73.1 37.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXS94303.1 - 1.5e-53 182.2 44.6 1.8e-53 181.9 44.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXS94303.1 - 1.3e-20 73.4 37.9 1.8e-20 73.0 37.9 1.1 1 0 0 1 1 1 1 Amino acid permease adh_short PF00106.25 KXS94304.1 - 7.8e-26 90.7 0.1 1.3e-24 86.8 0.0 2.2 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS94304.1 - 1.3e-16 60.9 0.1 2.7e-16 59.9 0.1 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS94304.1 - 5.4e-11 42.7 0.1 1.7e-10 41.1 0.0 1.9 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KXS94304.1 - 6.4e-05 22.5 0.5 0.00013 21.5 0.2 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family TFIIB PF00382.19 KXS94304.1 - 0.023 14.7 0.2 0.055 13.5 0.2 1.6 1 0 0 1 1 1 0 Transcription factor TFIIB repeat LRR_8 PF13855.6 KXS94305.1 - 0.0066 16.2 0.0 0.032 14.0 0.0 2.3 1 1 0 1 1 1 1 Leucine rich repeat F-box PF00646.33 KXS94305.1 - 0.014 15.2 0.9 0.034 14.0 0.9 1.6 1 0 0 1 1 1 0 F-box domain F-box-like_2 PF13013.6 KXS94305.1 - 0.16 11.9 0.1 0.66 10.0 0.1 2.0 2 1 0 2 2 2 0 F-box-like domain 2OG-FeII_Oxy_2 PF13532.6 KXS94306.1 - 4.2e-36 125.0 0.1 6.5e-36 124.4 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.12 KXS94306.1 - 0.0015 18.6 6.8 0.0036 17.4 6.8 1.6 1 0 0 1 1 1 1 GRF zinc finger DUF3865 PF12981.7 KXS94306.1 - 0.033 14.1 0.0 0.052 13.4 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3865) SIR2 PF02146.17 KXS94307.1 - 1.1e-57 194.8 0.0 1.7e-57 194.2 0.0 1.3 1 0 0 1 1 1 1 Sir2 family pPIWI_RE_Y PF18156.1 KXS94307.1 - 0.19 12.1 0.1 0.66 10.4 0.0 1.8 2 0 0 2 2 2 0 pPIWI_RE three-gene island domain Y ESSS PF10183.9 KXS94308.1 - 0.072 13.3 2.2 1.5 9.1 1.4 2.7 2 1 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) BPD_transp_1 PF00528.22 KXS94308.1 - 0.12 12.1 4.4 0.15 11.8 1.5 1.9 2 0 0 2 2 2 0 Binding-protein-dependent transport system inner membrane component ERGIC_N PF13850.6 KXS94308.1 - 0.13 12.6 0.0 1.1 9.6 0.0 2.2 2 0 0 2 2 2 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Zip PF02535.22 KXS94308.1 - 0.14 11.4 0.1 0.49 9.6 0.0 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter Wzy_C PF04932.15 KXS94308.1 - 0.84 9.3 3.2 11 5.6 3.7 2.3 2 1 0 2 2 2 0 O-Antigen ligase Beta_helix PF13229.6 KXS94309.1 - 1.5e-06 28.1 24.8 0.00012 22.0 18.6 2.3 1 1 1 2 2 2 2 Right handed beta helix region SET PF00856.28 KXS94311.1 - 1.7e-13 51.3 0.0 8.1e-12 45.8 0.0 2.9 2 1 0 2 2 2 1 SET domain TPR_12 PF13424.6 KXS94311.1 - 3e-07 30.6 17.3 0.00021 21.5 0.5 5.3 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXS94311.1 - 2e-05 24.4 7.2 0.46 10.7 0.7 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXS94311.1 - 0.0024 17.6 2.4 24 5.0 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KXS94311.1 - 0.0043 16.5 3.1 0.04 13.3 0.2 2.6 3 0 0 3 3 3 1 MalT-like TPR region TPR_14 PF13428.6 KXS94311.1 - 0.019 15.7 9.5 1.8 9.6 0.4 5.4 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF1391 PF07151.12 KXS94311.1 - 0.045 13.6 0.0 0.096 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1391) Tox-MPTase4 PF15640.6 KXS94311.1 - 0.052 13.4 0.1 0.16 11.9 0.0 1.8 2 0 0 2 2 2 0 Metallopeptidase toxin 4 TPR_16 PF13432.6 KXS94311.1 - 0.086 13.5 12.1 3.4 8.4 0.7 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXS94311.1 - 0.13 12.6 1.4 24 5.5 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3813 PF12758.7 KXS94311.1 - 0.48 10.8 4.9 2.6 8.4 1.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3813) Fungal_trans PF04082.18 KXS94312.1 - 4.5e-12 45.6 0.0 7.9e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 KXS94312.1 - 2.9e-08 33.8 8.7 9.8e-08 32.1 1.0 3.9 3 1 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 KXS94312.1 - 1.3e-07 31.6 14.7 0.00057 20.2 2.8 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type Zn_clus PF00172.18 KXS94312.1 - 4e-06 26.9 7.6 4e-06 26.9 7.6 2.2 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.6 KXS94312.1 - 0.0011 19.6 14.1 0.026 15.3 2.0 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger Skp1 PF01466.19 KXS94313.1 - 2.5e-28 97.9 0.5 5e-28 97.0 0.5 1.5 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 KXS94313.1 - 1.3e-21 76.5 0.4 3e-21 75.3 0.2 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Glyco_transf_22 PF03901.17 KXS94314.1 - 2.9e-59 201.4 18.4 3.7e-59 201.0 18.4 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF2177 PF09945.9 KXS94314.1 - 0.098 12.8 2.6 0.099 12.7 0.2 2.3 2 1 1 3 3 3 0 Predicted membrane protein (DUF2177) Acetyltransf_1 PF00583.25 KXS94317.1 - 8.8e-07 29.2 0.0 1.2e-06 28.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXS94317.1 - 2.2e-06 27.6 0.0 3.6e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXS94317.1 - 7.6e-05 23.1 0.0 0.00013 22.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FAT PF02259.23 KXS94318.1 - 9.4e-72 242.1 17.9 1.8e-71 241.1 8.2 2.9 3 0 0 3 3 3 2 FAT domain PI3_PI4_kinase PF00454.27 KXS94318.1 - 1e-30 107.4 0.4 4.3e-30 105.3 0.2 2.2 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 KXS94318.1 - 3.4e-07 30.0 0.1 8.3e-07 28.7 0.1 1.7 1 0 0 1 1 1 1 FATC domain Thymidylat_synt PF00303.19 KXS94318.1 - 0.036 13.2 0.8 0.095 11.8 0.8 1.6 1 0 0 1 1 1 0 Thymidylate synthase DUF5486 PF17588.2 KXS94318.1 - 2.9 7.8 4.7 2.4 8.1 0.2 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5486) NMO PF03060.15 KXS94319.1 - 6.2e-56 190.2 0.0 2.8e-54 184.7 0.0 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KXS94319.1 - 2.4e-13 49.8 0.0 2e-11 43.5 0.0 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KXS94319.1 - 0.0072 15.4 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KXS94319.1 - 0.17 11.0 0.4 0.95 8.5 0.2 2.1 1 1 1 2 2 2 0 Conserved region in glutamate synthase BAR PF03114.18 KXS94320.1 - 2.4e-45 155.0 11.0 3e-45 154.8 11.0 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 KXS94320.1 - 0.0016 17.6 3.9 0.0022 17.2 3.9 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Ribosomal_S10 PF00338.22 KXS94320.1 - 0.11 12.7 0.1 0.22 11.7 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein S10p/S20e KorB PF08535.10 KXS94321.1 - 0.059 13.4 0.1 0.22 11.6 0.0 1.9 2 0 0 2 2 2 0 KorB domain Asp-Al_Ex PF06826.12 KXS94324.1 - 0.042 13.7 0.1 0.064 13.1 0.1 1.2 1 0 0 1 1 1 0 Predicted Permease Membrane Region Cas_Cmr5 PF09701.10 KXS94326.1 - 0.11 12.8 0.0 0.16 12.3 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cmr5) Shugoshin_N PF07558.11 KXS94330.1 - 0.086 12.7 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Amidohydro_1 PF01979.20 KXS94336.1 - 2.3e-16 60.0 0.1 3e-16 59.7 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXS94336.1 - 1.8e-09 37.6 0.1 2.2e-09 37.3 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Aminotran_4 PF01063.19 KXS94337.1 - 1.3e-25 90.5 0.0 2.3e-25 89.8 0.0 1.4 1 1 0 1 1 1 1 Amino-transferase class IV GFO_IDH_MocA PF01408.22 KXS94338.1 - 7.5e-07 30.0 0.0 1.8e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Abhydrolase_1 PF00561.20 KXS94339.1 - 7.5e-44 150.3 1.0 8.9e-43 146.8 1.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXS94339.1 - 0.00013 22.7 0.2 0.00041 21.0 0.2 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXS94339.1 - 0.0011 18.3 0.1 0.41 9.9 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Say1_Mug180 PF10340.9 KXS94339.1 - 0.0028 16.6 0.0 0.0039 16.1 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_4 PF08386.10 KXS94339.1 - 0.024 14.8 0.0 0.059 13.5 0.0 1.7 1 0 0 1 1 1 0 TAP-like protein PhoH PF02562.16 KXS94339.1 - 0.07 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein PGA_cap PF09587.10 KXS94340.1 - 7.7e-63 212.3 0.0 1.2e-62 211.8 0.0 1.3 1 0 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap Ail_Lom PF06316.11 KXS94340.1 - 0.08 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Enterobacterial Ail/Lom protein Esterase PF00756.20 KXS94342.1 - 3.5e-06 26.8 0.0 8.4e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 KXS94342.1 - 0.016 14.7 0.0 0.25 10.8 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family TauD PF02668.16 KXS94343.1 - 3.4e-30 105.8 0.0 4.5e-30 105.3 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Methyltransf_25 PF13649.6 KXS94345.1 - 9.6e-06 26.2 0.0 2.8e-05 24.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS94345.1 - 0.0013 18.6 0.0 0.0031 17.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain ATP-grasp PF02222.22 KXS94345.1 - 0.011 15.3 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain Methyltransf_23 PF13489.6 KXS94345.1 - 0.021 14.7 0.0 0.045 13.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Tim17 PF02466.19 KXS94351.1 - 2e-07 31.3 11.2 3.3e-07 30.7 10.3 1.8 1 1 1 2 2 2 2 Tim17/Tim22/Tim23/Pmp24 family AAA PF00004.29 KXS94352.1 - 7.6e-38 129.9 0.0 1.6e-37 128.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KXS94352.1 - 2e-07 30.9 0.3 8.7e-07 28.9 0.0 2.3 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 KXS94352.1 - 4.4e-07 29.6 0.0 8.6e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KXS94352.1 - 2.8e-05 24.4 0.1 0.00017 21.8 0.1 2.3 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KXS94352.1 - 0.00021 21.1 0.0 0.00039 20.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KXS94352.1 - 0.00031 21.2 1.6 0.0055 17.1 0.1 3.3 4 1 0 4 4 4 1 AAA ATPase domain TIP49 PF06068.13 KXS94352.1 - 0.00088 18.6 0.1 0.0016 17.7 0.1 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 KXS94352.1 - 0.0024 17.9 0.0 0.0072 16.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KXS94352.1 - 0.0059 16.0 0.1 0.011 15.2 0.1 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 KXS94352.1 - 0.0062 16.7 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 KXS94352.1 - 0.0072 16.1 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF815 PF05673.13 KXS94352.1 - 0.011 14.9 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 KXS94352.1 - 0.02 15.4 0.0 0.064 13.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KXS94352.1 - 0.021 15.0 0.0 0.053 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KXS94352.1 - 0.036 13.6 0.0 0.2 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KXS94352.1 - 0.047 13.4 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KXS94352.1 - 0.1 12.6 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KXS94352.1 - 0.15 11.9 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 KXS94352.1 - 0.23 11.0 0.0 0.44 10.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 KXS94352.1 - 1.4 9.2 4.3 0.97 9.7 0.1 2.8 3 1 1 4 4 4 0 AAA domain DUF4482 PF14818.6 KXS94352.1 - 3.3 8.6 6.0 19 6.1 1.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) tRNA-synt_2 PF00152.20 KXS94353.1 - 1.8e-81 273.7 0.0 2.1e-81 273.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KXS94353.1 - 3.7e-07 30.0 0.0 7.7e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain SYS1 PF09801.9 KXS94354.1 - 8.6e-51 171.9 9.0 9.8e-51 171.7 9.0 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network Sugar_tr PF00083.24 KXS94355.1 - 2.5e-118 395.8 15.6 6e-118 394.6 15.6 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS94355.1 - 3.9e-27 95.1 36.3 1.2e-23 83.6 27.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXS94355.1 - 0.028 12.9 7.1 0.047 12.1 3.3 2.2 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Mito_carr PF00153.27 KXS94355.1 - 2.4 8.1 4.6 19 5.2 0.1 2.8 2 1 1 3 3 3 0 Mitochondrial carrier protein Sugar_tr PF00083.24 KXS94356.1 - 2.5e-118 395.8 15.6 6e-118 394.6 15.6 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS94356.1 - 3.9e-27 95.1 36.3 1.2e-23 83.6 27.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXS94356.1 - 0.028 12.9 7.1 0.047 12.1 3.3 2.2 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Mito_carr PF00153.27 KXS94356.1 - 2.4 8.1 4.6 19 5.2 0.1 2.8 2 1 1 3 3 3 0 Mitochondrial carrier protein Sugar_tr PF00083.24 KXS94357.1 - 2.5e-118 395.8 15.6 6e-118 394.6 15.6 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS94357.1 - 3.9e-27 95.1 36.3 1.2e-23 83.6 27.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXS94357.1 - 0.028 12.9 7.1 0.047 12.1 3.3 2.2 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Mito_carr PF00153.27 KXS94357.1 - 2.4 8.1 4.6 19 5.2 0.1 2.8 2 1 1 3 3 3 0 Mitochondrial carrier protein Sugar_tr PF00083.24 KXS94358.1 - 2.5e-118 395.8 15.6 6e-118 394.6 15.6 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS94358.1 - 3.9e-27 95.1 36.3 1.2e-23 83.6 27.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXS94358.1 - 0.028 12.9 7.1 0.047 12.1 3.3 2.2 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Mito_carr PF00153.27 KXS94358.1 - 2.4 8.1 4.6 19 5.2 0.1 2.8 2 1 1 3 3 3 0 Mitochondrial carrier protein Sugar_tr PF00083.24 KXS94359.1 - 2.5e-118 395.8 15.6 6e-118 394.6 15.6 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS94359.1 - 3.9e-27 95.1 36.3 1.2e-23 83.6 27.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXS94359.1 - 0.028 12.9 7.1 0.047 12.1 3.3 2.2 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Mito_carr PF00153.27 KXS94359.1 - 2.4 8.1 4.6 19 5.2 0.1 2.8 2 1 1 3 3 3 0 Mitochondrial carrier protein Glyoxalase_6 PF18029.1 KXS94362.1 - 5.6e-05 23.9 0.1 0.00017 22.3 0.1 1.8 1 1 0 1 1 1 1 Glyoxalase-like domain adh_short_C2 PF13561.6 KXS94363.1 - 1.3e-34 119.8 2.1 5.1e-34 117.8 2.1 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS94363.1 - 4.9e-26 91.4 0.4 7.5e-26 90.8 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS94363.1 - 0.008 16.1 1.2 0.0098 15.8 0.1 1.6 2 0 0 2 2 2 1 KR domain BolA PF01722.18 KXS94364.1 - 1.3e-13 51.1 0.0 3.6e-13 49.6 0.0 1.7 1 1 0 1 1 1 1 BolA-like protein BTB PF00651.31 KXS94365.1 - 0.1 12.8 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 BTB/POZ domain ProRS-C_1 PF09180.11 KXS94366.1 - 0.034 14.3 0.0 0.074 13.3 0.0 1.7 2 1 0 2 2 2 0 Prolyl-tRNA synthetase, C-terminal NIF PF03031.18 KXS94367.1 - 2.3e-54 183.4 0.3 3.1e-54 183.0 0.3 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase K1377 PF15352.6 KXS94367.1 - 6.8 4.8 11.0 2.3 6.4 8.5 1.4 1 1 0 1 1 1 0 Susceptibility to monomelic amyotrophy CBM_21 PF03370.13 KXS94368.1 - 3.5e-33 114.2 0.4 5.6e-33 113.5 0.4 1.3 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KXS94368.1 - 3.4e-08 33.9 1.8 7.3e-08 32.9 1.8 1.5 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) Methyltransf_12 PF08242.12 KXS94369.1 - 0.002 18.8 0.0 0.0029 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS94369.1 - 0.0043 17.7 0.0 0.0067 17.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS94369.1 - 0.11 13.2 0.0 0.17 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KXS94370.1 - 0.002 18.8 0.0 0.0029 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS94370.1 - 0.0043 17.7 0.0 0.0067 17.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS94370.1 - 0.11 13.2 0.0 0.17 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain p450 PF00067.22 KXS94371.1 - 9e-70 235.7 0.0 1.2e-69 235.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4598 PF15370.6 KXS94373.1 - 4.1e-19 69.1 2.6 4.1e-19 69.1 2.6 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4598) AF-4 PF05110.13 KXS94373.1 - 0.14 10.3 24.6 0.18 9.9 24.6 1.3 1 0 0 1 1 1 0 AF-4 proto-oncoprotein VGPC1_C PF16799.5 KXS94373.1 - 0.72 9.9 2.3 0.73 9.9 0.0 2.1 2 0 0 2 2 2 0 C-terminal membrane-localisation domain of ion-channel, VCN1 QWRF PF04484.12 KXS94373.1 - 1.2 8.8 11.6 1.5 8.5 11.6 1.3 1 0 0 1 1 1 0 QWRF family Macoilin PF09726.9 KXS94373.1 - 1.2 7.6 10.2 1.4 7.4 10.2 1.1 1 0 0 1 1 1 0 Macoilin family Nop25 PF09805.9 KXS94373.1 - 3.2 8.2 6.8 3.1 8.3 1.2 2.1 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) PI3K_1B_p101 PF10486.9 KXS94373.1 - 3.2 5.4 8.5 3.1 5.5 8.5 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Asp PF00026.23 KXS94374.1 - 1.8e-05 24.3 0.1 0.00012 21.7 0.1 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease VSP PF03302.13 KXS94374.1 - 0.00051 19.0 0.7 0.00089 18.2 0.7 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein PTP_tm PF18861.1 KXS94374.1 - 0.0034 17.4 0.1 0.0059 16.6 0.1 1.3 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J Rax2 PF12768.7 KXS94374.1 - 0.0042 16.6 0.0 0.0074 15.8 0.0 1.3 1 0 0 1 1 1 1 Cortical protein marker for cell polarity SKG6 PF08693.10 KXS94374.1 - 0.0063 15.9 1.3 0.0063 15.9 1.3 2.4 2 0 0 2 2 2 1 Transmembrane alpha-helix domain CcmD PF04995.14 KXS94374.1 - 0.052 13.6 0.6 0.1 12.7 0.6 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Phage_Coat_B PF05356.11 KXS94374.1 - 0.15 12.0 0.2 0.39 10.7 0.2 1.7 1 0 0 1 1 1 0 Phage Coat protein B CoxIIa PF08113.11 KXS94374.1 - 1.2 9.0 5.6 2.7 7.9 5.6 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IIa family DUF3933 PF13069.6 KXS94375.1 - 0.1 12.5 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3933) Polysacc_synt_C PF14667.6 KXS94376.1 - 0.035 14.2 7.8 0.036 14.1 6.8 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain CSG2 PF16965.5 KXS94376.1 - 0.17 10.8 0.6 0.28 10.1 0.6 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator DUF5079 PF16882.5 KXS94376.1 - 0.2 11.5 0.1 0.28 11.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5079) IncD PF17628.2 KXS94376.1 - 0.2 11.4 2.7 0.21 11.4 1.2 1.8 2 0 0 2 2 2 0 Inclusion membrane protein D Phage_holin_3_6 PF07332.11 KXS94376.1 - 0.49 10.5 15.6 0.017 15.1 7.7 2.3 1 1 1 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF5129 PF17173.4 KXS94377.1 - 0.012 14.8 0.2 0.019 14.1 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5129) Mtc PF03820.17 KXS94378.1 - 2.6e-122 407.8 0.2 2.9e-122 407.6 0.2 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier DUF963 PF06131.11 KXS94378.1 - 0.18 11.2 2.5 0.32 10.4 0.8 2.2 2 0 0 2 2 2 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) Mtc PF03820.17 KXS94379.1 - 2.6e-122 407.8 0.2 2.9e-122 407.6 0.2 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier DUF963 PF06131.11 KXS94379.1 - 0.18 11.2 2.5 0.32 10.4 0.8 2.2 2 0 0 2 2 2 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) Mtc PF03820.17 KXS94381.1 - 2.6e-122 407.8 0.2 2.9e-122 407.6 0.2 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier DUF963 PF06131.11 KXS94381.1 - 0.18 11.2 2.5 0.32 10.4 0.8 2.2 2 0 0 2 2 2 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) ELO PF01151.18 KXS94384.1 - 7.6e-81 271.3 6.5 1e-80 270.9 6.5 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family DUF4795 PF16043.5 KXS94384.1 - 0.042 13.4 1.8 0.65 9.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) Apolipoprotein PF01442.18 KXS94384.1 - 2.4 8.0 18.0 0.65 9.8 10.4 3.0 3 1 0 3 3 3 0 Apolipoprotein A1/A4/E domain YtxH PF12732.7 KXS94384.1 - 4.6 7.9 18.0 3.5 8.2 1.8 4.0 4 0 0 4 4 4 0 YtxH-like protein SNARE PF05739.19 KXS94384.1 - 7.3 6.7 7.4 0.34 11.0 0.8 2.3 2 1 0 2 2 2 0 SNARE domain Fungal_trans PF04082.18 KXS94388.1 - 6.2e-15 54.9 0.0 1.1e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF969 PF06149.12 KXS94388.1 - 0.083 12.3 0.1 0.18 11.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF969) Abhydrolase_6 PF12697.7 KXS94389.1 - 1.4e-06 29.1 1.0 2.9e-06 28.1 1.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Sec6 PF06046.13 KXS94390.1 - 2.1e-158 528.3 11.2 2.8e-158 527.8 11.2 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec6 CUT PF02376.15 KXS94390.1 - 0.11 12.7 0.3 14 5.9 0.0 3.6 3 0 0 3 3 3 0 CUT domain Helo_like_N PF17111.5 KXS94390.1 - 0.23 10.8 2.8 2.8 7.3 0.0 2.9 3 0 0 3 3 3 0 Fungal N-terminal domain of STAND proteins RGS12_us1 PF16613.5 KXS94391.1 - 0.019 15.3 0.3 0.023 15.0 0.3 1.3 1 1 0 1 1 1 0 Unstructured region of RGS12 DNA_pol_B_3 PF08408.10 KXS94391.1 - 0.077 13.2 0.0 0.087 13.0 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase family B viral insert Peptidase_M18 PF02127.15 KXS94391.1 - 0.19 10.4 0.0 0.22 10.3 0.0 1.1 1 0 0 1 1 1 0 Aminopeptidase I zinc metalloprotease (M18) zf-GRF PF06839.12 KXS94393.1 - 4.5e-07 29.8 6.3 9e-07 28.9 6.3 1.5 1 0 0 1 1 1 1 GRF zinc finger PKcGMP_CC PF16808.5 KXS94393.1 - 4.7 7.2 5.8 0.75 9.7 0.6 2.4 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Na_trans_assoc PF06512.13 KXS94394.1 - 2.3 8.5 9.2 0.33 11.2 1.4 2.5 3 0 0 3 3 3 0 Sodium ion transport-associated OSCP PF00213.18 KXS94396.1 - 7.2e-46 156.4 6.4 8.8e-46 156.2 6.4 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit TFIIE_beta PF02186.15 KXS94396.1 - 0.011 15.9 0.1 0.028 14.7 0.1 1.6 1 0 0 1 1 1 0 TFIIE beta subunit core domain polyprenyl_synt PF00348.17 KXS94397.1 - 6e-65 218.8 0.0 8e-65 218.4 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase Ribosomal_L7Ae PF01248.26 KXS94399.1 - 1.8e-20 72.4 0.5 1.9e-14 53.1 0.0 2.4 2 0 0 2 2 2 2 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_L30 PF00327.20 KXS94403.1 - 1.9e-12 46.9 0.1 2.5e-12 46.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e HET PF06985.11 KXS94408.1 - 5.9e-35 120.8 0.1 8e-35 120.3 0.1 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF2279 PF10043.9 KXS94408.1 - 0.048 14.4 0.0 0.11 13.3 0.0 1.5 1 0 0 1 1 1 0 Predicted periplasmic lipoprotein (DUF2279) Stealth_CR4 PF17103.5 KXS94408.1 - 0.082 12.8 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Stealth protein CR4, conserved region 4 Alpha-amylase PF00128.24 KXS94409.1 - 0.017 14.7 0.0 0.023 14.3 0.0 1.1 1 0 0 1 1 1 0 Alpha amylase, catalytic domain Alpha-amylase PF00128.24 KXS94410.1 - 0.017 14.7 0.0 0.023 14.3 0.0 1.1 1 0 0 1 1 1 0 Alpha amylase, catalytic domain Podoplanin PF05808.11 KXS94411.1 - 3.7e-05 23.9 0.1 5.6e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Podoplanin DUF347 PF03988.12 KXS94411.1 - 0.03 14.5 0.6 0.052 13.7 0.6 1.4 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) EphA2_TM PF14575.6 KXS94411.1 - 0.031 15.2 0.0 0.062 14.2 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Rax2 PF12768.7 KXS94411.1 - 0.098 12.1 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity SKG6 PF08693.10 KXS94411.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Med3 PF11593.8 KXS94411.1 - 0.14 11.3 5.5 0.17 11.0 5.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Alpha_GJ PF03229.13 KXS94411.1 - 0.19 12.3 12.8 0.43 11.1 11.5 2.1 2 0 0 2 2 2 0 Alphavirus glycoprotein J MGC-24 PF05283.11 KXS94411.1 - 0.37 11.2 5.0 0.85 10.1 5.0 1.6 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin FSA_C PF10479.9 KXS94411.1 - 1.4 7.0 3.8 1.7 6.7 3.8 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF515 PF04415.12 KXS94411.1 - 3.5 5.9 6.4 5.1 5.4 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) TIM21 PF08294.11 KXS94412.1 - 8.6e-42 142.4 0.0 1.1e-41 142.1 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 KXS94412.1 - 9.9e-06 25.3 0.0 8.6e-05 22.3 0.0 2.1 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 GST_N_3 PF13417.6 KXS94413.1 - 1e-10 41.9 0.0 1.8e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXS94413.1 - 4e-08 33.5 0.0 7e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXS94413.1 - 2.1e-07 31.1 0.0 3.3e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KXS94413.1 - 1.7e-06 28.2 0.0 5.3e-06 26.6 0.0 1.8 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXS94413.1 - 2.5e-05 24.4 0.0 3.5e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXS94413.1 - 5.2e-05 23.2 0.1 0.00031 20.7 0.1 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain HA2 PF04408.23 KXS94414.1 - 1.8e-19 70.0 0.9 2.1e-18 66.6 0.0 2.9 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KXS94414.1 - 2e-15 56.9 0.0 4.7e-15 55.7 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KXS94414.1 - 1.7e-14 54.1 0.0 4.2e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXS94414.1 - 6.2e-08 32.6 0.1 1.1e-07 31.8 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KXS94414.1 - 1.4e-05 25.4 0.1 3e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXS94414.1 - 0.00014 21.6 0.0 0.00014 21.6 0.0 2.1 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.6 KXS94414.1 - 0.00024 21.5 0.1 0.00061 20.2 0.1 1.6 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 KXS94414.1 - 0.00042 20.0 0.3 0.0011 18.6 0.3 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain DUF2075 PF09848.9 KXS94414.1 - 0.00044 19.6 0.0 0.00044 19.6 0.0 2.1 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 KXS94414.1 - 0.00071 18.7 0.6 0.0018 17.4 0.6 1.6 1 1 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.15 KXS94414.1 - 0.0044 17.0 0.0 2.6 8.0 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_14 PF13173.6 KXS94414.1 - 0.012 15.6 0.2 0.11 12.5 0.2 2.4 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 KXS94414.1 - 0.019 14.3 0.0 0.04 13.3 0.0 1.4 1 0 0 1 1 1 0 KaiC Flavi_DEAD PF07652.14 KXS94414.1 - 0.028 14.4 0.1 0.056 13.4 0.1 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain Microtub_bd PF16796.5 KXS94414.1 - 0.094 12.6 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 Microtubule binding NACHT PF05729.12 KXS94414.1 - 0.11 12.4 0.4 1.3 8.9 0.1 2.4 2 0 0 2 2 2 0 NACHT domain cobW PF02492.19 KXS94414.1 - 0.11 12.0 0.1 1.1 8.8 0.0 2.5 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 KXS94414.1 - 0.17 12.4 0.3 0.46 11.0 0.0 1.9 2 0 0 2 2 1 0 ABC transporter AAA_33 PF13671.6 KXS94414.1 - 0.44 10.7 4.2 0.36 11.0 0.1 2.9 2 2 0 2 2 2 0 AAA domain Glyco_hydro_1 PF00232.18 KXS94415.1 - 1.1e-108 363.6 0.1 1.4e-108 363.3 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Gpr1_Fun34_YaaH PF01184.19 KXS94416.1 - 3.3e-32 111.8 20.1 4.2e-32 111.4 20.1 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family UL41A PF17591.2 KXS94416.1 - 4.4 7.5 5.1 6.3 7.0 0.1 2.8 2 1 1 3 3 3 0 Herpesvirus UL41A Glyoxalase PF00903.25 KXS94417.1 - 1.6e-20 73.6 0.2 4e-16 59.4 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KXS94417.1 - 4.3e-12 46.3 0.1 1.4e-06 28.6 0.0 2.6 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KXS94417.1 - 2e-05 24.8 0.0 0.25 11.4 0.0 3.9 3 1 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_5 PF14696.6 KXS94417.1 - 0.0015 18.7 0.0 0.11 12.6 0.0 2.8 3 0 0 3 3 3 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal CmlA_N PF18456.1 KXS94417.1 - 0.14 11.5 0.0 6.1 6.1 0.0 2.1 2 0 0 2 2 2 0 Diiron non-heme beta-hydroxylase N-terminal domain LRR19-TM PF15176.6 KXS94418.1 - 0.12 12.4 2.6 1 9.4 0.2 2.5 3 0 0 3 3 3 0 Leucine-rich repeat family 19 TM domain P5CR_dimer PF14748.6 KXS94419.1 - 2.4e-36 124.1 0.6 2.4e-36 124.1 0.6 2.4 3 0 0 3 3 3 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KXS94419.1 - 1.5e-19 70.3 1.4 3.7e-19 69.1 1.4 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 KXS94419.1 - 0.00023 21.2 1.6 0.0023 18.0 1.6 2.3 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.20 KXS94419.1 - 0.00081 19.5 0.5 0.0023 18.0 0.2 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 KXS94419.1 - 0.00084 19.5 0.2 0.0017 18.5 0.2 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase PDH PF02153.17 KXS94419.1 - 0.0091 15.0 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_7 PF13241.6 KXS94419.1 - 0.014 15.8 0.2 0.03 14.7 0.2 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding CoA_binding PF02629.19 KXS94419.1 - 0.021 15.5 0.3 0.47 11.2 0.4 2.3 2 0 0 2 2 2 0 CoA binding domain UDPG_MGDP_dh_C PF03720.15 KXS94419.1 - 0.022 15.2 0.1 0.18 12.2 0.0 2.1 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain DpaA_N PF16924.5 KXS94419.1 - 0.13 12.3 0.0 0.46 10.6 0.0 1.9 1 1 0 1 1 1 0 Dipicolinate synthase subunit A N-terminal domain TAFII28 PF04719.14 KXS94420.1 - 2.5e-21 75.6 0.0 2e-18 66.3 0.0 2.3 2 0 0 2 2 2 2 hTAFII28-like protein conserved region BLOC1S3 PF15753.5 KXS94420.1 - 0.06 13.5 4.7 0.065 13.3 0.0 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 Apt1 PF10351.9 KXS94420.1 - 0.68 8.7 3.2 1 8.1 3.2 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Spt5_N PF11942.8 KXS94420.1 - 2.5 9.2 11.6 2.3 9.2 1.2 2.7 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal ABC1 PF03109.16 KXS94421.1 - 1.1e-34 119.1 0.0 4.7e-34 117.1 0.0 2.0 2 0 0 2 2 2 1 ABC1 family Acyl_transf_3 PF01757.22 KXS94422.1 - 2.9e-28 98.9 35.4 4e-28 98.5 35.4 1.3 1 0 0 1 1 1 1 Acyltransferase family Amidase PF01425.21 KXS94424.1 - 1.6e-106 357.0 0.0 2.6e-106 356.3 0.0 1.3 1 0 0 1 1 1 1 Amidase EHN PF06441.12 KXS94424.1 - 9.9e-27 93.4 0.0 2.1e-26 92.4 0.0 1.6 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KXS94424.1 - 3.5e-05 23.6 0.0 7.2e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold p450 PF00067.22 KXS94425.1 - 3.5e-47 161.2 0.0 6e-31 107.7 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 PH_10 PF15411.6 KXS94426.1 - 9e-25 87.3 0.0 1.5e-24 86.6 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain VWA PF00092.28 KXS94426.1 - 8.6e-11 42.4 0.0 1.5e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KXS94426.1 - 2.5e-07 30.8 0.1 3.2e-06 27.2 0.1 2.4 1 1 0 1 1 1 1 von Willebrand factor type A domain zf-RING_5 PF14634.6 KXS94426.1 - 0.0082 16.1 8.0 0.014 15.3 8.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KXS94426.1 - 0.026 14.8 7.4 0.049 14.0 7.4 1.5 1 0 0 1 1 1 0 Ring finger domain DUF1147 PF06615.11 KXS94426.1 - 0.17 12.0 0.2 0.38 10.8 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1147) zf-C3HC4_3 PF13920.6 KXS94426.1 - 0.18 11.7 4.4 0.37 10.7 4.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXS94426.1 - 0.38 11.1 4.2 0.85 9.9 4.2 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING-like PF08746.11 KXS94426.1 - 0.56 10.6 6.4 1 9.7 6.4 1.4 1 0 0 1 1 1 0 RING-like domain Zn_ribbon_17 PF17120.5 KXS94426.1 - 0.61 9.8 8.0 0.31 10.7 4.7 1.9 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 KXS94426.1 - 0.78 9.5 2.8 1.8 8.4 2.8 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4 PF00097.25 KXS94426.1 - 0.89 9.5 8.0 1.7 8.6 8.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CAP59_mtransfer PF11735.8 KXS94428.1 - 6e-73 245.5 0.0 7.9e-73 245.1 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 SCA7 PF08313.12 KXS94429.1 - 9.5e-31 105.5 0.9 9.5e-31 105.5 0.9 1.9 2 0 0 2 2 2 1 SCA7, zinc-binding domain Sgf11 PF08209.11 KXS94429.1 - 0.068 12.8 1.1 0.11 12.0 1.1 1.4 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) RNF220 PF15926.5 KXS94429.1 - 0.15 11.7 7.6 0.15 11.7 6.1 1.6 1 1 0 1 1 1 0 E3 ubiquitin-protein ligase RNF220 CDC45 PF02724.14 KXS94429.1 - 1 7.6 11.2 1.3 7.2 11.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Macoilin PF09726.9 KXS94429.1 - 2.6 6.5 9.9 3.1 6.2 9.9 1.1 1 0 0 1 1 1 0 Macoilin family CCDC106 PF15794.5 KXS94429.1 - 3.4 7.3 14.6 6.1 6.5 13.1 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 DUF4820 PF16091.5 KXS94429.1 - 4.7 6.5 6.2 10 5.4 6.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) ICMT PF04140.14 KXS94430.1 - 3e-27 94.9 0.3 6.4e-27 93.8 0.1 1.6 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KXS94430.1 - 1.7e-11 44.4 0.4 1.7e-11 44.4 0.4 2.0 2 0 0 2 2 2 1 Phospholipid methyltransferase NnrU PF07298.11 KXS94430.1 - 1.2e-06 28.2 4.1 2.3e-06 27.3 0.5 2.0 2 0 0 2 2 2 1 NnrU protein DUF1295 PF06966.12 KXS94430.1 - 0.00014 21.5 2.0 0.00014 21.5 2.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) DUF3382 PF11862.8 KXS94430.1 - 0.49 10.7 3.6 1 9.7 0.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3382) HEAT PF02985.22 KXS94431.1 - 0.035 14.3 0.1 1.3 9.5 0.0 3.7 3 0 0 3 3 3 0 HEAT repeat F-box-like_2 PF13013.6 KXS94432.1 - 0.091 12.7 0.0 0.21 11.6 0.0 1.8 1 1 0 1 1 1 0 F-box-like domain zf-C2H2 PF00096.26 KXS94433.1 - 1.3e-18 66.3 27.5 6.3e-05 23.2 1.7 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXS94433.1 - 7.6e-15 54.6 28.3 3e-06 27.4 1.2 5.5 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXS94433.1 - 5.6e-10 39.2 24.9 0.0072 17.1 1.3 4.8 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXS94433.1 - 1.1e-05 25.6 0.6 0.67 10.3 0.0 4.4 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXS94433.1 - 0.021 15.2 13.6 0.45 11.0 0.1 4.4 5 0 0 5 5 4 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KXS94433.1 - 0.034 13.9 0.8 0.034 13.9 0.8 3.2 3 0 0 3 3 3 0 zinc-finger C2H2-type zf_UBZ PF18439.1 KXS94433.1 - 0.081 12.5 1.3 2 8.1 0.2 2.8 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_aberr PF17017.5 KXS94433.1 - 0.1 12.7 1.3 5.3 7.2 0.0 2.2 2 0 0 2 2 2 0 Aberrant zinc-finger C1_4 PF07975.12 KXS94433.1 - 0.19 12.0 0.8 3 8.2 0.0 2.7 2 1 1 3 3 3 0 TFIIH C1-like domain T3SS_needle_E PF08988.10 KXS94433.1 - 1.1 9.4 5.7 0.34 11.1 0.7 2.6 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle FOXP-CC PF16159.5 KXS94433.1 - 1.4 9.6 5.4 26 5.5 0.1 3.5 3 1 1 4 4 3 0 FOXP coiled-coil domain XPA_N PF01286.18 KXS94433.1 - 4.2 7.5 6.4 1.4 9.0 0.5 2.8 3 0 0 3 3 3 0 XPA protein N-terminal zf-CRD PF17979.1 KXS94433.1 - 6.5 6.8 7.7 18 5.4 1.7 2.6 1 1 1 2 2 2 0 Cysteine rich domain with multizinc binding regions LIM PF00412.22 KXS94433.1 - 7.1 6.9 6.8 16 5.8 0.2 3.0 1 1 2 3 3 3 0 LIM domain Zn-ribbon_8 PF09723.10 KXS94433.1 - 7.3 6.8 7.9 25 5.1 1.2 3.1 1 1 2 3 3 3 0 Zinc ribbon domain zf-C2H2 PF00096.26 KXS94434.1 - 9.2e-19 66.8 27.5 5.6e-05 23.4 1.7 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXS94434.1 - 4.6e-15 55.3 28.3 2.7e-06 27.6 1.2 5.5 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXS94434.1 - 3.8e-10 39.7 24.9 0.0064 17.2 1.3 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXS94434.1 - 7.8e-06 26.0 0.6 0.6 10.5 0.0 4.3 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXS94434.1 - 0.015 15.7 13.6 0.4 11.1 0.1 4.4 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KXS94434.1 - 0.031 14.1 0.8 0.031 14.1 0.8 3.2 3 0 0 3 3 3 0 zinc-finger C2H2-type zf_UBZ PF18439.1 KXS94434.1 - 0.063 12.9 1.3 1.8 8.3 0.2 2.9 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_aberr PF17017.5 KXS94434.1 - 0.082 13.0 1.4 4.7 7.3 0.0 2.3 2 0 0 2 2 2 0 Aberrant zinc-finger C1_4 PF07975.12 KXS94434.1 - 0.15 12.3 0.9 2.6 8.3 0.0 2.8 2 1 1 3 3 3 0 TFIIH C1-like domain FOXP-CC PF16159.5 KXS94434.1 - 0.91 10.2 5.2 23 5.7 0.1 3.6 3 1 1 4 4 4 0 FOXP coiled-coil domain T3SS_needle_E PF08988.10 KXS94434.1 - 0.95 9.7 5.7 0.3 11.3 0.7 2.6 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle zf-CRD PF17979.1 KXS94434.1 - 3.3 7.8 7.7 15 5.6 1.7 3.0 2 1 1 3 3 3 0 Cysteine rich domain with multizinc binding regions Zn-ribbon_8 PF09723.10 KXS94434.1 - 6.3 7.0 8.1 19 5.5 1.0 3.1 1 1 1 3 3 3 0 Zinc ribbon domain LIM PF00412.22 KXS94434.1 - 7.3 6.9 7.3 16 5.8 0.5 3.0 1 1 2 3 3 3 0 LIM domain zf-C2H2 PF00096.26 KXS94435.1 - 4.1e-19 67.9 27.5 4.5e-05 23.7 1.7 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXS94435.1 - 1.7e-15 56.6 28.3 2.1e-06 27.9 1.2 5.4 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXS94435.1 - 1.7e-10 40.8 24.9 0.0051 17.5 1.3 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXS94435.1 - 4.1e-06 26.9 0.6 0.48 10.8 0.0 4.3 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXS94435.1 - 0.0054 17.1 13.6 0.32 11.4 0.1 4.7 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KXS94435.1 - 0.025 14.4 0.8 0.025 14.4 0.8 3.2 3 0 0 3 3 3 0 zinc-finger C2H2-type zf_UBZ PF18439.1 KXS94435.1 - 0.038 13.6 1.3 1.4 8.6 0.2 2.9 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_aberr PF17017.5 KXS94435.1 - 0.069 13.3 1.7 3.7 7.7 0.1 2.2 2 0 0 2 2 2 0 Aberrant zinc-finger C1_4 PF07975.12 KXS94435.1 - 0.11 12.8 1.1 2.1 8.7 0.0 2.8 2 1 1 3 3 3 0 TFIIH C1-like domain FOXP-CC PF16159.5 KXS94435.1 - 0.49 11.1 5.2 18 6.1 0.1 3.7 3 1 1 4 4 4 0 FOXP coiled-coil domain Zn-ribbon_8 PF09723.10 KXS94435.1 - 4.3 7.5 8.0 15 5.8 0.9 3.0 1 1 0 2 2 2 0 Zinc ribbon domain LIM PF00412.22 KXS94435.1 - 4.4 7.6 7.3 13 6.1 0.6 3.0 1 1 2 3 3 3 0 LIM domain R3H PF01424.22 KXS94436.1 - 0.028 14.4 0.1 0.052 13.5 0.1 1.4 1 0 0 1 1 1 0 R3H domain BTB PF00651.31 KXS94437.1 - 0.00049 20.3 0.0 0.0008 19.6 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain TPT PF03151.16 KXS94438.1 - 7.4e-30 104.3 21.5 8.9e-30 104.0 21.5 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KXS94438.1 - 0.016 14.4 20.7 0.09 12.0 20.7 1.9 1 1 0 1 1 1 0 UAA transporter family EamA PF00892.20 KXS94438.1 - 0.12 12.6 38.7 0.024 14.8 15.7 2.6 3 0 0 3 3 3 0 EamA-like transporter family Apolipoprotein PF01442.18 KXS94441.1 - 0.0049 16.8 4.5 0.0082 16.0 4.5 1.4 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 KXS94441.1 - 0.029 15.0 7.1 0.83 10.3 0.1 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 KXS94441.1 - 0.1 13.2 15.4 0.36 11.4 13.7 2.7 2 1 0 2 2 2 0 YtxH-like protein Perilipin PF03036.16 KXS94441.1 - 0.25 10.3 7.1 0.25 10.3 0.0 2.1 1 1 0 2 2 2 0 Perilipin family Rhodanese PF00581.20 KXS94445.1 - 6e-12 46.0 0.0 1.3e-11 45.0 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain NAD_binding_8 PF13450.6 KXS94446.1 - 1.3e-08 34.9 0.1 5.7e-08 32.9 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KXS94446.1 - 1.3e-07 31.3 0.0 2e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 KXS94446.1 - 0.0032 16.7 0.2 0.019 14.2 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXS94446.1 - 0.0035 16.6 0.1 0.0055 16.0 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXS94446.1 - 0.0078 15.5 0.1 0.013 14.8 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KXS94446.1 - 0.013 14.7 0.1 0.024 13.9 0.1 1.3 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 KXS94446.1 - 0.034 13.5 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.18 KXS94446.1 - 0.036 14.3 0.1 0.21 11.8 0.0 2.1 2 0 0 2 2 2 0 TrkA-N domain DAO PF01266.24 KXS94446.1 - 0.041 13.5 0.0 0.065 12.8 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXS94446.1 - 0.053 12.6 0.3 0.34 9.9 0.1 2.0 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 KXS94446.1 - 0.13 11.2 0.1 0.22 10.5 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 KXS94447.1 - 3.4e-19 69.3 1.7 1.6e-10 40.8 0.5 3.0 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KXS94447.1 - 4e-06 26.3 0.0 0.0012 18.2 0.0 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXS94447.1 - 5.3e-06 25.4 0.1 4e-05 22.5 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 KXS94447.1 - 1e-05 25.7 0.0 2.1e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXS94447.1 - 0.00038 20.9 0.0 0.25 11.9 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXS94447.1 - 0.00063 19.1 0.0 0.048 12.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXS94447.1 - 0.0012 18.6 0.1 0.0029 17.3 0.0 1.6 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXS94447.1 - 0.0017 17.5 0.0 0.0027 16.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 KXS94447.1 - 0.0093 15.3 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 KXS94447.1 - 0.019 14.1 0.0 0.053 12.6 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 KXS94447.1 - 0.019 15.4 0.0 0.06 13.8 0.0 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding Glu_dehyd_C PF16912.5 KXS94447.1 - 0.035 13.6 0.0 0.063 12.8 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Trp_halogenase PF04820.14 KXS94447.1 - 0.058 12.2 0.0 0.63 8.8 0.1 2.0 2 0 0 2 2 2 0 Tryptophan halogenase GYF_2 PF14237.6 KXS94447.1 - 0.061 13.1 0.1 0.14 11.9 0.1 1.6 1 0 0 1 1 1 0 GYF domain 2 GIDA PF01134.22 KXS94447.1 - 0.079 12.0 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.17 KXS94447.1 - 0.082 12.1 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Shikimate_DH PF01488.20 KXS94447.1 - 0.14 12.2 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_4 PF01565.23 KXS94448.1 - 4.8e-10 39.3 0.0 6.7e-09 35.6 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain ALO PF04030.14 KXS94448.1 - 6.9e-08 32.6 3.1 2.9e-07 30.6 3.1 1.9 1 1 0 1 1 1 1 D-arabinono-1,4-lactone oxidase Chol_subst-bind PF09129.11 KXS94448.1 - 0.042 12.8 6.8 0.81 8.6 6.6 2.7 1 1 0 1 1 1 0 Cholesterol oxidase, substrate-binding FAD_binding_4 PF01565.23 KXS94449.1 - 5e-10 39.3 0.0 6.9e-09 35.6 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain ALO PF04030.14 KXS94449.1 - 1.1e-08 35.2 2.4 3e-08 33.8 2.4 1.7 1 1 0 1 1 1 1 D-arabinono-1,4-lactone oxidase Chol_subst-bind PF09129.11 KXS94449.1 - 0.068 12.1 7.4 1.8 7.5 7.3 2.8 1 1 0 1 1 1 0 Cholesterol oxidase, substrate-binding Spt20 PF12090.8 KXS94454.1 - 0.00085 19.0 22.6 0.0014 18.3 22.6 1.4 1 0 0 1 1 1 1 Spt20 family Rrn6 PF10214.9 KXS94454.1 - 0.0011 17.6 15.5 0.0015 17.2 15.5 1.3 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor TMEM247 PF15444.6 KXS94454.1 - 0.0022 18.0 4.2 0.0035 17.4 4.2 1.3 1 0 0 1 1 1 1 Transmembrane protein 247 SRP-alpha_N PF04086.13 KXS94454.1 - 0.0061 16.5 9.7 0.0086 16.0 9.7 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal Roughex PF06020.11 KXS94454.1 - 0.026 13.7 6.9 0.037 13.1 6.9 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Presenilin PF01080.17 KXS94454.1 - 0.031 13.1 5.9 0.036 12.9 5.9 1.1 1 0 0 1 1 1 0 Presenilin eIF-3_zeta PF05091.12 KXS94454.1 - 0.068 12.1 8.0 0.099 11.6 8.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) AAA_23 PF13476.6 KXS94454.1 - 0.12 12.9 5.4 0.15 12.6 5.4 1.2 1 0 0 1 1 1 0 AAA domain DUF908 PF06012.12 KXS94454.1 - 0.13 11.6 8.6 0.19 11.1 8.6 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) SpoIIP PF07454.11 KXS94454.1 - 0.13 11.7 4.7 0.17 11.3 4.7 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Hydin_ADK PF17213.3 KXS94454.1 - 0.18 12.0 4.4 0.33 11.2 4.4 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain CPSF100_C PF13299.6 KXS94454.1 - 0.19 11.9 3.7 0.31 11.2 3.7 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Lin-8 PF03353.15 KXS94454.1 - 0.25 10.9 9.3 0.33 10.5 9.3 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist RR_TM4-6 PF06459.12 KXS94454.1 - 0.26 11.1 3.9 0.37 10.6 3.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Coilin_N PF15862.5 KXS94454.1 - 0.33 10.8 6.8 0.53 10.1 6.8 1.3 1 0 0 1 1 1 0 Coilin N-terminus DUF4770 PF15994.5 KXS94454.1 - 0.39 10.9 8.9 0.64 10.2 8.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) API5 PF05918.11 KXS94454.1 - 0.48 9.2 8.7 0.7 8.6 8.7 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) TMEM51 PF15345.6 KXS94454.1 - 0.5 10.2 13.3 0.72 9.6 13.3 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 DUF4834 PF16118.5 KXS94454.1 - 0.73 10.8 9.8 1.4 9.9 9.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF775 PF05603.12 KXS94454.1 - 0.84 9.1 7.6 1.3 8.5 7.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF775) DUF4551 PF15087.6 KXS94454.1 - 0.89 8.3 9.8 1.2 7.8 9.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Plasmodium_Vir PF05795.11 KXS94454.1 - 0.91 8.9 3.6 1.2 8.4 3.6 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Rxt3 PF08642.10 KXS94454.1 - 1 10.1 4.9 2 9.2 4.9 1.4 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 Connexin PF00029.19 KXS94454.1 - 1.2 8.8 3.0 1.8 8.3 3.0 1.2 1 0 0 1 1 1 0 Connexin DUF4407 PF14362.6 KXS94454.1 - 1.4 8.2 8.1 2.5 7.4 8.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.19 KXS94454.1 - 1.5 6.6 5.4 2 6.2 5.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ndc1_Nup PF09531.10 KXS94454.1 - 1.7 7.2 15.6 3 6.4 15.6 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TERB2 PF15101.6 KXS94454.1 - 1.8 8.6 10.8 3.1 7.8 10.8 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PRTP PF01366.18 KXS94454.1 - 2.1 6.3 6.8 3 5.8 6.8 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Hid1 PF12722.7 KXS94454.1 - 2.9 5.9 7.8 3.2 5.7 7.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein EIIBC-GUT_N PF03612.14 KXS94454.1 - 3.2 7.5 8.0 5.1 6.8 8.0 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus SPX PF03105.19 KXS94454.1 - 3.3 7.5 16.0 4.5 7.1 16.0 1.2 1 0 0 1 1 1 0 SPX domain Herpes_UL32 PF06070.11 KXS94454.1 - 3.8 5.1 12.4 4.8 4.8 12.4 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 DUF3464 PF11947.8 KXS94454.1 - 5 6.9 8.7 12 5.7 8.7 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 PAT1 PF09770.9 KXS94454.1 - 7.5 4.7 23.6 9 4.4 23.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF5344 PF17279.2 KXS94455.1 - 0.025 15.2 0.2 0.046 14.3 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5344) AIP3 PF03915.13 KXS94455.1 - 0.095 11.8 3.1 0.11 11.5 3.1 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 Rad17 PF03215.15 KXS94458.1 - 2.2e-27 96.2 0.0 7.8e-27 94.4 0.0 1.9 2 0 0 2 2 2 1 Rad17 P-loop domain AAA PF00004.29 KXS94458.1 - 2.4e-06 28.0 0.0 5.3e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXS94458.1 - 9.6e-05 22.8 0.3 0.0007 20.0 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KXS94458.1 - 0.00017 21.9 0.0 0.00035 20.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXS94458.1 - 0.00081 19.2 0.5 0.0021 17.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KXS94458.1 - 0.0019 18.3 0.1 0.015 15.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 KXS94458.1 - 0.0033 17.4 0.0 0.0068 16.4 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_6 PF12774.7 KXS94458.1 - 0.0048 15.9 0.0 0.0096 14.9 0.0 1.4 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region Cytidylate_kin PF02224.18 KXS94458.1 - 0.016 15.0 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase T2SSE PF00437.20 KXS94458.1 - 0.021 13.9 0.0 0.055 12.5 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_18 PF13238.6 KXS94458.1 - 0.027 15.0 0.4 0.19 12.3 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KXS94458.1 - 0.031 14.6 0.0 0.093 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KXS94458.1 - 0.036 13.8 0.0 0.083 12.6 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 KXS94458.1 - 0.048 14.2 0.0 0.18 12.4 0.0 2.0 1 0 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 KXS94458.1 - 0.051 13.6 0.1 0.13 12.2 0.1 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 KXS94458.1 - 0.057 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KXS94458.1 - 0.063 12.8 0.0 0.28 10.7 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_14 PF13173.6 KXS94458.1 - 0.14 12.2 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KXS94458.1 - 0.26 11.0 4.0 0.34 10.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain CIA30 PF08547.12 KXS94459.1 - 9.5e-37 126.5 0.1 1.3e-36 126.0 0.1 1.2 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) DUF5075 PF16825.5 KXS94459.1 - 0.073 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 IGP family C-type lectin domain DUF2458 PF10454.9 KXS94459.1 - 0.18 11.5 0.1 0.3 10.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) bZIP_1 PF00170.21 KXS94460.1 - 0.00019 21.5 6.7 0.00034 20.6 6.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXS94460.1 - 0.0019 18.2 6.3 0.0033 17.5 6.3 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KXS94460.1 - 0.96 10.0 9.6 1 9.9 8.6 1.6 1 1 0 1 1 1 0 bZIP Maf transcription factor FAD_binding_4 PF01565.23 KXS94461.1 - 3.7e-17 62.4 0.0 6.9e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Cpn60_TCP1 PF00118.24 KXS94462.1 - 5.7e-149 496.9 6.0 6.4e-149 496.7 6.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pectinesterase PF01095.19 KXS94463.1 - 7.1e-49 166.1 4.1 9.1e-49 165.8 4.1 1.0 1 0 0 1 1 1 1 Pectinesterase Alpha-amylase PF00128.24 KXS94464.1 - 1.2e-108 363.7 0.1 1.9e-108 363.1 0.1 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain MFS_1 PF07690.16 KXS94464.1 - 3.8e-44 151.1 42.9 1.6e-42 145.7 40.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS94464.1 - 2.7e-09 36.4 7.9 2.7e-09 36.4 7.9 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter FPN1 PF06963.12 KXS94464.1 - 4.8e-06 25.4 0.1 4.8e-06 25.4 0.1 2.0 2 0 0 2 2 2 1 Ferroportin1 (FPN1) Malt_amylase_C PF16657.5 KXS94464.1 - 6.4e-06 26.2 0.0 1.9e-05 24.7 0.0 1.9 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 KXS94464.1 - 0.012 14.8 0.0 0.024 13.8 0.0 1.4 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain PAP2_C PF14360.6 KXS94464.1 - 0.37 11.3 1.9 1.5 9.4 1.9 2.1 1 0 0 1 1 1 0 PAP2 superfamily C-terminal OATP PF03137.20 KXS94464.1 - 0.39 8.9 1.6 11 4.1 1.5 2.7 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF1129 PF06570.11 KXS94464.1 - 0.42 10.1 2.7 0.93 8.9 2.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) MFS_1 PF07690.16 KXS94465.1 - 3.2e-45 154.6 42.7 3.7e-43 147.8 41.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS94465.1 - 1.6e-09 37.2 9.0 1.6e-09 37.2 9.0 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter FPN1 PF06963.12 KXS94465.1 - 1.7e-06 26.9 0.1 1.7e-06 26.9 0.1 2.4 3 0 0 3 3 3 1 Ferroportin1 (FPN1) DUF1129 PF06570.11 KXS94465.1 - 0.31 10.5 4.3 0.56 9.7 2.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) OATP PF03137.20 KXS94465.1 - 0.69 8.1 5.8 4.9 5.3 1.7 3.1 2 2 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family PAP2_C PF14360.6 KXS94465.1 - 0.9 10.1 5.0 0.68 10.5 1.9 2.5 2 0 0 2 2 2 0 PAP2 superfamily C-terminal PIRT PF15099.6 KXS94465.1 - 2.2 7.9 4.3 0.74 9.4 0.1 2.2 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Alpha-amylase PF00128.24 KXS94466.1 - 2.1e-109 366.2 0.1 3.5e-109 365.4 0.1 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 KXS94466.1 - 2.2e-06 27.7 0.0 7.8e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 KXS94466.1 - 0.0048 16.0 0.0 0.009 15.1 0.0 1.3 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain AAA PF00004.29 KXS94467.1 - 1.5e-40 138.7 0.0 2.6e-40 137.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXS94467.1 - 2.5e-05 24.0 0.0 7.3e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KXS94467.1 - 7.4e-05 23.0 0.0 0.0059 16.9 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 KXS94467.1 - 8.3e-05 22.6 0.1 0.00062 19.8 0.0 2.5 4 1 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KXS94467.1 - 0.00044 20.4 0.0 0.0013 18.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KXS94467.1 - 0.00053 20.4 0.1 0.011 16.1 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 KXS94467.1 - 0.0014 17.8 0.0 0.0026 17.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KXS94467.1 - 0.0094 15.7 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 KXS94467.1 - 0.021 15.2 0.1 0.15 12.4 0.0 2.4 3 0 0 3 3 3 0 RNA helicase AAA_28 PF13521.6 KXS94467.1 - 0.029 14.6 0.0 0.063 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KXS94467.1 - 0.033 13.7 0.0 0.095 12.2 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 KXS94467.1 - 0.052 13.7 0.0 0.095 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KXS94467.1 - 0.075 12.8 0.1 0.27 10.9 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_3 PF07726.11 KXS94467.1 - 0.083 12.7 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KXS94467.1 - 0.1 12.7 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KXS94467.1 - 0.15 12.6 0.0 0.49 11.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KXS94467.1 - 0.15 11.8 0.7 0.54 10.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KXS94467.1 - 0.16 11.3 0.0 0.36 10.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 KXS94467.1 - 0.21 11.5 1.1 9.8 6.0 0.0 2.9 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea F-box-like PF12937.7 KXS94468.1 - 1.3e-07 31.4 0.1 2.5e-07 30.5 0.1 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS94468.1 - 4.4e-05 23.3 0.0 9.9e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 F-box domain PEX11 PF05648.14 KXS94469.1 - 1.1e-33 116.5 0.1 1.8e-33 115.9 0.1 1.2 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Lactamase_B PF00753.27 KXS94469.1 - 6.7e-16 58.9 4.2 9.9e-16 58.3 4.2 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXS94469.1 - 0.00034 20.2 0.1 0.00072 19.1 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain zf-RING_2 PF13639.6 KXS94476.1 - 4e-14 52.7 6.1 4e-14 52.7 6.1 2.2 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXS94476.1 - 2.4e-12 46.5 5.5 2.4e-12 46.5 5.5 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXS94476.1 - 7.9e-10 38.9 4.4 2.2e-09 37.5 4.4 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KXS94476.1 - 1.1e-09 37.9 3.1 3.1e-09 36.4 3.1 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KXS94476.1 - 1.1e-08 34.7 5.6 1.1e-08 34.7 5.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KXS94476.1 - 5e-08 32.9 1.3 1.2e-07 31.7 1.3 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 KXS94476.1 - 6.4e-08 32.5 0.8 2.9e-07 30.4 0.9 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KXS94476.1 - 1.7e-06 27.9 4.8 1.7e-06 27.9 4.8 2.1 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KXS94476.1 - 1.9e-06 27.6 4.1 1.9e-06 27.6 4.1 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KXS94476.1 - 6.7e-05 22.4 4.4 6.7e-05 22.4 4.4 2.3 3 0 0 3 3 2 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 KXS94476.1 - 0.0003 20.6 4.6 0.0003 20.6 4.6 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 Zn-ribbon_8 PF09723.10 KXS94476.1 - 0.011 15.9 5.3 0.88 9.7 0.0 3.3 3 0 0 3 3 3 0 Zinc ribbon domain zf-C3HC4_4 PF15227.6 KXS94476.1 - 0.012 15.8 4.3 0.012 15.8 4.3 2.1 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.7 KXS94476.1 - 0.017 15.2 3.5 0.043 13.9 3.5 1.7 1 1 0 1 1 1 0 RING-variant domain zf-C3H2C3 PF17122.5 KXS94476.1 - 0.023 14.7 1.4 0.023 14.7 1.4 2.1 2 0 0 2 2 2 0 Zinc-finger zf-Nse PF11789.8 KXS94476.1 - 0.025 14.4 3.0 0.05 13.4 3.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 KXS94476.1 - 0.15 12.2 5.3 0.97 9.7 5.3 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 KXS94476.1 - 0.16 12.3 5.1 0.57 10.5 5.1 2.0 1 0 0 1 1 1 0 RING-like domain PHD PF00628.29 KXS94476.1 - 0.29 11.1 8.2 0.24 11.3 5.2 2.3 2 0 0 2 2 2 0 PHD-finger zinc_ribbon_9 PF14369.6 KXS94476.1 - 2.5 8.5 5.9 19 5.6 0.1 3.4 3 0 0 3 3 3 0 zinc-ribbon zf-RING_4 PF14570.6 KXS94476.1 - 4.9 7.0 10.5 0.38 10.6 2.8 2.9 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain Prok-RING_1 PF14446.6 KXS94476.1 - 6 6.9 14.8 3.8 7.5 1.6 4.2 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 PITH PF06201.13 KXS94477.1 - 2.9e-41 141.2 0.1 4e-41 140.7 0.1 1.2 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 KXS94477.1 - 5.5e-28 97.0 0.0 1e-27 96.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KXS94477.1 - 6.3e-06 26.6 0.2 5.2e-05 23.7 0.2 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 KXS94477.1 - 1e-05 25.0 0.0 2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 KXS94477.1 - 1.3e-05 25.4 0.0 0.00076 19.8 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like Redoxin PF08534.10 KXS94477.1 - 0.0026 17.5 0.2 0.6 9.8 0.1 2.3 1 1 1 2 2 2 2 Redoxin Thioredoxin_9 PF14595.6 KXS94477.1 - 0.0031 17.3 0.0 0.0055 16.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 KXS94477.1 - 0.047 13.6 0.0 0.13 12.2 0.0 1.6 1 1 0 1 1 1 0 AhpC/TSA family HAD PF12710.7 KXS94479.1 - 0.0049 17.3 1.0 0.19 12.1 0.2 2.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF507 PF04368.13 KXS94480.1 - 0.0066 16.4 0.4 0.0095 15.9 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF507) PIN_9 PF18477.1 KXS94480.1 - 0.096 13.0 0.1 0.19 12.1 0.1 1.5 1 0 0 1 1 1 0 PIN like domain HAD PF12710.7 KXS94481.1 - 0.0049 17.3 1.0 0.19 12.1 0.2 2.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Fer2_3 PF13085.6 KXS94482.1 - 1.7e-32 111.6 0.0 2.9e-32 110.9 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 KXS94482.1 - 4.1e-09 36.8 7.1 4.1e-09 36.8 7.1 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KXS94482.1 - 1.8e-07 31.5 7.3 1.8e-07 31.5 7.3 2.8 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 KXS94482.1 - 2.8e-06 27.3 4.1 2.8e-06 27.3 4.1 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 KXS94482.1 - 0.0047 16.9 2.7 0.011 15.7 0.3 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 KXS94482.1 - 0.024 15.2 6.5 0.024 15.2 6.5 2.4 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 KXS94482.1 - 0.045 13.9 2.6 0.49 10.6 0.1 2.7 3 0 0 3 3 3 0 4Fe-4S dicluster domain MgtC PF02308.16 KXS94483.1 - 0.01 16.2 7.0 0.014 15.7 7.0 1.2 1 0 0 1 1 1 1 MgtC family E1-E2_ATPase PF00122.20 KXS94483.1 - 0.013 15.0 0.8 0.019 14.5 0.8 1.2 1 0 0 1 1 1 0 E1-E2 ATPase DUF3054 PF11255.8 KXS94483.1 - 0.059 13.9 2.7 0.095 13.2 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3054) YbgS PF13985.6 KXS94483.1 - 0.12 12.7 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 YbgS-like protein AC_N PF16214.5 KXS94483.1 - 0.18 10.9 3.0 0.3 10.2 3.0 1.3 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Ribosomal_L36e PF01158.18 KXS94484.1 - 3.2e-43 145.9 4.7 3.7e-43 145.7 4.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e PBS_linker_poly PF00427.21 KXS94484.1 - 0.019 15.0 0.1 0.022 14.8 0.1 1.1 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide HTH_38 PF13936.6 KXS94484.1 - 0.039 13.7 0.1 0.42 10.4 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain LemA PF04011.12 KXS94484.1 - 0.13 12.1 0.2 0.16 11.8 0.2 1.1 1 0 0 1 1 1 0 LemA family G-patch_2 PF12656.7 KXS94486.1 - 6.1e-22 77.5 0.5 6.1e-22 77.5 0.5 2.7 2 0 0 2 2 2 1 G-patch domain G-patch PF01585.23 KXS94486.1 - 0.00037 20.3 2.0 0.00092 19.1 2.0 1.8 1 0 0 1 1 1 1 G-patch domain MDM31_MDM32 PF08118.11 KXS94487.1 - 6.7e-244 810.4 0.9 8.2e-244 810.1 0.9 1.1 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins Shadoo PF14999.6 KXS94487.1 - 0.029 14.5 0.1 0.095 12.8 0.1 1.9 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective BTB PF00651.31 KXS94488.1 - 4.3e-09 36.6 0.2 4.3e-08 33.4 0.0 2.3 2 1 1 3 3 3 1 BTB/POZ domain Shigella_OspC PF06128.11 KXS94488.1 - 0.12 12.0 1.2 0.59 9.8 1.2 1.8 1 1 0 1 1 1 0 Shigella flexneri OspC protein AAA_lid_4 PF17864.1 KXS94488.1 - 0.15 11.9 0.0 0.44 10.3 0.0 1.7 2 0 0 2 2 2 0 RuvB AAA lid domain TUG-UBL1 PF11470.8 KXS94489.1 - 2.6e-24 85.2 0.5 9.5e-24 83.4 0.5 2.0 1 0 0 1 1 1 1 TUG ubiquitin-like domain UBX PF00789.20 KXS94489.1 - 4.2e-06 26.9 0.0 3.9e-05 23.8 0.0 2.4 2 0 0 2 2 2 1 UBX domain RBD PF02196.15 KXS94489.1 - 4.9e-06 26.5 0.1 2.4e-05 24.3 0.1 2.1 2 0 0 2 2 2 1 Raf-like Ras-binding domain Rad60-SLD PF11976.8 KXS94489.1 - 0.0048 16.7 0.2 3.9 7.4 0.0 2.6 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like UN_NPL4 PF11543.8 KXS94489.1 - 0.029 14.8 1.8 0.46 11.0 0.0 3.0 4 0 0 4 4 4 0 Nuclear pore localisation protein NPL4 SIX1_SD PF16878.5 KXS94489.1 - 0.034 14.6 0.2 0.071 13.6 0.2 1.5 1 0 0 1 1 1 0 Transcriptional regulator, SIX1, N-terminal SD domain ubiquitin PF00240.23 KXS94489.1 - 0.038 13.8 0.0 0.24 11.2 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin family PB1 PF00564.24 KXS94489.1 - 0.08 12.9 0.0 0.45 10.5 0.0 2.3 1 0 0 1 1 1 0 PB1 domain PhyH PF05721.13 KXS94490.1 - 3e-17 63.6 0.0 4.6e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 KXS94490.1 - 0.03 14.7 0.0 0.067 13.6 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Phage_coat PF09063.10 KXS94490.1 - 0.21 11.6 0.0 0.83 9.7 0.0 1.8 2 0 0 2 2 2 0 Phage PP7 coat protein MOSC PF03473.17 KXS94491.1 - 5.8e-30 104.0 0.0 8.8e-30 103.4 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KXS94491.1 - 6.1e-19 68.1 0.0 1e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain DUF3602 PF12223.8 KXS94492.1 - 7.1e-16 58.6 5.1 8.3e-12 45.5 0.7 3.0 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) DnaJ PF00226.31 KXS94495.1 - 5.3e-05 23.3 0.0 0.00017 21.6 0.0 1.9 1 0 0 1 1 1 1 DnaJ domain Borrelia_P83 PF05262.11 KXS94495.1 - 0.18 10.3 21.9 0.25 9.8 21.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4614 PF15391.6 KXS94495.1 - 0.7 9.9 11.1 1.9 8.5 11.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) PPP4R2 PF09184.11 KXS94495.1 - 2.3 7.7 14.5 3.3 7.2 14.5 1.2 1 0 0 1 1 1 0 PPP4R2 SpoIIP PF07454.11 KXS94495.1 - 5.4 6.4 11.8 9.8 5.5 5.9 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF2868 PF11067.8 KXS94495.1 - 6.4 6.2 10.7 3.3 7.1 8.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2868) C2 PF00168.30 KXS94497.1 - 6.1e-16 58.6 0.0 1.2e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 C2 domain Asp PF00026.23 KXS94498.1 - 3.4e-06 26.7 0.2 1.2e-05 25.0 0.2 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease SKG6 PF08693.10 KXS94498.1 - 0.0068 15.8 0.8 0.013 14.9 0.8 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain VSP PF03302.13 KXS94498.1 - 0.01 14.7 0.1 0.018 13.9 0.1 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein Rax2 PF12768.7 KXS94498.1 - 0.15 11.5 0.0 0.34 10.3 0.0 1.6 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Actin PF00022.19 KXS94499.1 - 3.6e-124 414.5 0.0 1.7e-123 412.2 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KXS94499.1 - 0.00046 19.1 0.1 0.077 11.8 0.0 2.4 2 1 0 2 2 2 2 MreB/Mbl protein Sugar_tr PF00083.24 KXS94500.1 - 8.3e-81 272.1 23.0 9.8e-81 271.9 23.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS94500.1 - 1.1e-15 57.5 33.5 1.1e-15 57.5 33.5 2.2 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXS94500.1 - 0.0002 20.1 22.1 0.012 14.2 9.4 2.7 2 1 0 2 2 2 2 MFS/sugar transport protein EBP PF05241.12 KXS94500.1 - 0.016 14.7 0.5 0.016 14.7 0.5 2.2 3 0 0 3 3 3 0 Emopamil binding protein BSD PF03909.17 KXS94500.1 - 0.17 11.9 1.3 3.7 7.6 0.0 2.4 2 0 0 2 2 2 0 BSD domain Oxysterol_BP PF01237.18 KXS94502.1 - 3.1e-115 385.0 0.0 1.9e-114 382.4 0.0 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 KXS94502.1 - 2.5e-36 123.8 0.2 7.2e-36 122.4 0.2 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KXS94502.1 - 4.8e-06 27.0 0.0 1.1e-05 25.9 0.0 1.7 1 0 0 1 1 1 1 PH domain DUF321 PF03778.13 KXS94502.1 - 0.1 12.3 0.1 0.46 10.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF321) UQ_con PF00179.26 KXS94503.1 - 2.3e-38 131.0 0.0 3.2e-38 130.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXS94503.1 - 0.034 13.8 0.0 0.041 13.6 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B Arylsulfotran_2 PF14269.6 KXS94505.1 - 5.3e-33 114.7 0.4 1e-32 113.7 0.4 1.5 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KXS94505.1 - 3e-11 42.8 0.0 8.7e-10 38.0 0.0 2.2 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) DUF3328 PF11807.8 KXS94506.1 - 1.4e-40 139.5 1.0 1.7e-40 139.2 1.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Glyco_transf_90 PF05686.12 KXS94507.1 - 9.5e-20 70.9 1.7 6.7e-17 61.5 1.3 3.0 2 1 0 2 2 2 2 Glycosyl transferase family 90 SNF2_N PF00176.23 KXS94508.1 - 1.1e-63 215.1 0.1 2.5e-63 213.9 0.1 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXS94508.1 - 1e-18 67.7 0.0 3e-18 66.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXS94508.1 - 9.7e-09 35.4 0.2 3.3e-08 33.7 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KXS94508.1 - 0.00054 19.2 0.5 0.0016 17.6 0.0 1.9 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 TFIIF_beta PF02270.15 KXS94508.1 - 0.04 14.0 0.1 0.12 12.5 0.1 1.8 1 0 0 1 1 1 0 TFIIF, beta subunit HTH domain DUF3328 PF11807.8 KXS94509.1 - 1.1e-17 64.6 9.9 1.9e-16 60.5 9.9 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) bZIP_1 PF00170.21 KXS94510.1 - 2.1e-08 34.2 9.4 2.1e-08 34.2 9.4 2.3 2 1 0 2 2 2 1 bZIP transcription factor Sortilin_C PF15901.5 KXS94510.1 - 0.0093 16.3 0.5 0.018 15.4 0.5 1.4 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal bZIP_2 PF07716.15 KXS94510.1 - 0.54 10.4 12.6 0.78 9.9 5.2 2.9 1 1 1 2 2 2 0 Basic region leucine zipper Arylsulfotran_2 PF14269.6 KXS94511.1 - 2e-39 135.8 0.0 2.8e-39 135.3 0.0 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KXS94511.1 - 1.6e-10 40.4 0.1 3.2e-09 36.2 0.1 2.5 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) RINGv PF12906.7 KXS94512.1 - 1.1e-05 25.5 5.8 2.3e-05 24.4 5.8 1.6 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.8 KXS94512.1 - 0.00011 22.3 2.2 0.00024 21.2 2.2 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.6 KXS94512.1 - 0.32 11.4 9.2 0.85 10.0 9.2 1.8 1 1 0 1 1 1 0 Ring finger domain SQHop_cyclase_N PF13249.6 KXS94514.1 - 5.2e-87 291.6 0.4 1.7e-84 283.4 0.0 3.0 3 0 0 3 3 3 1 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 KXS94514.1 - 1.2e-85 287.4 0.3 1.5e-80 270.7 0.1 3.5 3 1 0 3 3 3 2 Squalene-hopene cyclase C-terminal domain Prenyltrans PF00432.21 KXS94514.1 - 3.9e-16 58.5 18.5 1.7e-06 27.7 0.1 6.6 7 0 0 7 7 7 4 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 KXS94514.1 - 0.00014 21.0 0.2 0.039 13.0 0.0 3.2 4 0 0 4 4 4 2 A-macroglobulin TED domain Pec_lyase PF09492.10 KXS94514.1 - 0.00023 20.6 0.0 0.81 9.0 0.0 4.0 3 1 0 4 4 4 1 Pectic acid lyase Glyco_hydro_cc PF11790.8 KXS94514.1 - 0.0063 16.1 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core MBOAT_2 PF13813.6 KXS94515.1 - 1.5e-17 63.7 4.3 3.5e-17 62.5 4.3 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family p450 PF00067.22 KXS94516.1 - 1.8e-15 56.7 0.0 4.5e-15 55.4 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Prenyltransf PF01255.19 KXS94524.1 - 6.9e-82 274.3 0.0 1.1e-81 273.6 0.0 1.3 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase DUF4129 PF13559.6 KXS94524.1 - 0.003 17.8 0.0 0.011 16.0 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) ImmE5 PF11480.8 KXS94524.1 - 0.16 12.5 0.0 0.99 9.9 0.0 2.3 3 0 0 3 3 3 0 Colicin-E5 Imm protein HET PF06985.11 KXS94525.1 - 8.7e-33 113.7 0.0 1.6e-32 112.9 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FBPase PF00316.20 KXS94526.1 - 1.2e-70 236.8 0.0 2.1e-70 236.1 0.0 1.4 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain NAD_binding_2 PF03446.15 KXS94526.1 - 1.3e-32 113.2 0.1 2.4e-32 112.3 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KXS94526.1 - 3.4e-18 66.1 0.0 6.8e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase DnaJ PF00226.31 KXS94527.1 - 0.038 14.1 0.8 0.18 11.9 0.8 2.0 1 1 0 1 1 1 0 DnaJ domain Shugoshin_N PF07558.11 KXS94530.1 - 0.032 14.1 0.2 0.032 14.1 0.2 4.3 4 1 1 5 5 5 0 Shugoshin N-terminal coiled-coil region Pox_A_type_inc PF04508.12 KXS94530.1 - 0.44 10.5 8.8 1.8 8.6 0.2 4.5 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat DHBP_synthase PF00926.19 KXS94531.1 - 8.6e-81 270.1 0.0 9.9e-81 269.9 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Cupin_1 PF00190.22 KXS94537.1 - 2.1e-37 128.1 0.0 1.5e-18 66.8 0.0 2.3 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 KXS94537.1 - 8.2e-25 86.3 0.0 1.1e-12 47.4 0.0 2.7 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KXS94537.1 - 4.3e-08 32.7 0.0 0.006 16.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) MannoseP_isomer PF01050.18 KXS94537.1 - 1.4e-06 28.3 0.0 4.8e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase AraC_binding PF02311.19 KXS94537.1 - 1.6e-05 24.8 0.0 0.0055 16.6 0.0 2.5 2 0 0 2 2 2 2 AraC-like ligand binding domain 3-HAO PF06052.12 KXS94537.1 - 3.2e-05 23.6 0.0 0.00013 21.7 0.0 1.9 2 0 0 2 2 2 1 3-hydroxyanthranilic acid dioxygenase Auxin_BP PF02041.16 KXS94537.1 - 0.0089 15.7 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Auxin binding protein Cupin_6 PF12852.7 KXS94537.1 - 0.024 14.4 0.0 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 Cupin Cupin_4 PF08007.12 KXS94537.1 - 0.054 12.9 0.1 0.47 9.9 0.0 2.3 2 1 1 3 3 3 0 Cupin superfamily protein ARD PF03079.14 KXS94537.1 - 0.21 11.8 0.0 13 5.9 0.0 2.2 2 0 0 2 2 2 0 ARD/ARD' family EMP24_GP25L PF01105.24 KXS94538.1 - 1.7e-39 135.7 0.0 2e-39 135.4 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD KCT2 PF17818.1 KXS94539.1 - 0.095 12.8 0.2 0.095 12.8 0.2 3.0 2 1 1 3 3 3 0 Keratinocyte-associated gene product TolA_bind_tri PF16331.5 KXS94539.1 - 0.44 10.7 9.6 0.31 11.1 4.1 2.6 2 0 0 2 2 2 0 TolA binding protein trimerisation Com_YlbF PF06133.11 KXS94539.1 - 2.7 8.7 7.6 2.4 8.8 0.4 2.6 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA DUF465 PF04325.13 KXS94539.1 - 4.5 7.4 6.3 0.7 10.0 0.8 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF465) Amidohydro_1 PF01979.20 KXS94540.1 - 1.4e-73 248.1 0.2 2e-73 247.7 0.2 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 KXS94540.1 - 1.2e-55 187.1 3.7 2.3e-55 186.1 3.7 1.5 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 KXS94540.1 - 2e-40 136.7 0.4 4.5e-40 135.6 0.1 1.8 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.18 KXS94540.1 - 4e-38 129.7 0.1 8.8e-38 128.6 0.1 1.6 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_3 PF07969.11 KXS94540.1 - 1.4e-08 34.6 0.1 7.7e-07 28.9 0.0 2.6 2 1 0 2 2 2 1 Amidohydrolase family ADH_N PF08240.12 KXS94542.1 - 2.1e-21 75.8 3.9 3.2e-21 75.2 3.9 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXS94542.1 - 1.4e-17 63.9 0.0 2.3e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXS94542.1 - 2e-10 41.8 0.0 3.9e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KXS94542.1 - 9.6e-05 21.8 0.0 0.00015 21.1 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KXS94542.1 - 0.0056 16.1 0.1 0.0092 15.4 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_N PF08240.12 KXS94543.1 - 1.8e-21 76.0 3.9 2.8e-21 75.5 3.9 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXS94543.1 - 1.3e-17 64.0 0.0 2e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXS94543.1 - 1.8e-10 42.0 0.0 3.3e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KXS94543.1 - 8.5e-05 21.9 0.0 0.00013 21.3 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KXS94543.1 - 0.005 16.2 0.1 0.0082 15.5 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PLAC PF08686.11 KXS94544.1 - 0.062 14.1 0.5 0.062 14.1 0.5 1.7 2 0 0 2 2 2 0 PLAC (protease and lacunin) domain DUF349 PF03993.12 KXS94545.1 - 0.01 16.1 2.4 0.021 15.1 0.8 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) AAA_assoc PF14363.6 KXS94545.1 - 0.11 12.8 0.3 0.35 11.2 0.0 1.9 2 0 0 2 2 2 0 Domain associated at C-terminal with AAA DUF1418 PF07214.12 KXS94545.1 - 0.17 11.7 1.3 0.44 10.4 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) Pex24p PF06398.11 KXS94546.1 - 8.1e-07 28.3 3.0 8.1e-07 28.3 3.0 1.7 2 0 0 2 2 2 1 Integral peroxisomal membrane peroxin Ricin_B_lectin PF00652.22 KXS94547.1 - 0.023 15.0 2.1 0.096 12.9 0.4 2.1 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain Glyco_hydro_28 PF00295.17 KXS94548.1 - 7.2e-47 160.0 7.3 1.4e-46 159.0 7.3 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Apolipoprotein PF01442.18 KXS94549.1 - 0.00021 21.2 5.5 0.00094 19.1 5.6 1.7 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 KXS94549.1 - 0.0027 17.8 8.6 0.0055 16.8 8.3 1.7 1 1 1 2 2 2 1 Apolipophorin-III precursor (apoLp-III) DUF4455 PF14643.6 KXS94549.1 - 0.0072 15.0 1.0 0.0081 14.9 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4455) DUF883 PF05957.13 KXS94549.1 - 0.045 14.4 8.0 0.26 11.9 7.1 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF3713 PF12506.8 KXS94549.1 - 0.052 13.9 4.0 1.2 9.5 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3713) DUF4085 PF13315.6 KXS94549.1 - 0.077 12.6 0.9 0.12 12.0 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4085) OrfB_IS605 PF01385.19 KXS94549.1 - 0.12 12.6 1.6 0.17 12.1 1.0 1.7 1 1 1 2 2 2 0 Probable transposase YtxH PF12732.7 KXS94549.1 - 0.26 11.8 24.1 0.038 14.5 13.2 3.1 1 1 1 2 2 2 0 YtxH-like protein Metal_resist PF13801.6 KXS94549.1 - 0.27 11.4 2.3 0.6 10.3 2.3 1.7 1 1 0 1 1 1 0 Heavy-metal resistance OmpH PF03938.14 KXS94549.1 - 0.42 10.9 11.3 0.67 10.3 11.3 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) RRF PF01765.19 KXS94549.1 - 0.43 10.5 9.2 0.38 10.7 7.6 1.7 1 1 0 1 1 1 0 Ribosome recycling factor Syntaxin PF00804.25 KXS94549.1 - 0.66 9.6 4.3 0.87 9.2 4.3 1.2 1 0 0 1 1 1 0 Syntaxin CDPS PF16715.5 KXS94549.1 - 1 9.0 3.7 1.7 8.3 3.5 1.4 1 1 0 1 1 1 0 Cyclodipeptide synthase ATP-synt_B PF00430.18 KXS94549.1 - 1.1 9.4 17.8 6.9 6.8 9.8 2.3 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) RSRP PF17069.5 KXS94549.1 - 2.4 7.6 7.5 3 7.3 7.5 1.0 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 V-ATPase_G_2 PF16999.5 KXS94549.1 - 3.9 7.9 14.7 5 7.6 3.8 2.6 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit Thiolase_N PF00108.23 KXS94550.1 - 5.1e-12 45.7 0.0 5.9e-11 42.2 0.0 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXS94550.1 - 3.3e-11 42.9 0.2 1.7e-10 40.6 0.2 2.2 1 1 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KXS94550.1 - 9.6e-06 25.3 0.4 4.3e-05 23.2 0.5 1.9 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KXS94550.1 - 5e-05 23.1 0.0 0.00016 21.5 0.1 1.8 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SpoVAD PF07451.11 KXS94550.1 - 0.03 13.0 0.2 0.087 11.5 0.1 1.7 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) Ketoacyl-synt_C PF02801.22 KXS94550.1 - 0.074 13.1 0.2 2.5 8.1 0.0 2.9 3 0 0 3 3 3 0 Beta-ketoacyl synthase, C-terminal domain AAA PF00004.29 KXS94560.1 - 1.6e-18 67.4 0.0 2.6e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 KXS94560.1 - 0.00052 19.8 0.0 0.00092 19.0 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 KXS94560.1 - 0.006 16.9 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KXS94560.1 - 0.012 15.5 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 KXS94560.1 - 0.015 14.8 0.0 0.026 14.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 KXS94560.1 - 0.02 15.3 0.1 0.061 13.7 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain Drc1-Sld2 PF11719.8 KXS94560.1 - 0.023 14.2 4.1 0.03 13.9 4.1 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein RNA_helicase PF00910.22 KXS94560.1 - 0.077 13.4 0.0 0.22 11.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase TrwB_AAD_bind PF10412.9 KXS94560.1 - 0.097 11.6 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Mg_chelatase PF01078.21 KXS94560.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 KXS94560.1 - 0.21 11.3 3.2 2.6 7.8 2.4 2.6 1 1 0 2 2 2 0 AAA domain YL1 PF05764.13 KXS94560.1 - 4.8 7.2 9.7 0.5 10.4 5.4 1.6 2 0 0 2 2 2 0 YL1 nuclear protein EMP24_GP25L PF01105.24 KXS94562.1 - 3.1e-47 160.9 0.0 3.9e-47 160.6 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD UPF0242 PF06785.11 KXS94563.1 - 0.0067 16.6 10.9 0.0074 16.4 2.8 2.2 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus Med4 PF10018.9 KXS94563.1 - 0.008 15.9 2.5 0.018 14.7 1.0 2.1 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 DUF2333 PF10095.9 KXS94563.1 - 0.046 12.7 4.7 0.066 12.2 4.7 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) NuA4 PF09340.10 KXS94563.1 - 0.073 13.0 0.8 7.2 6.6 0.0 2.7 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 SPATA1_C PF15743.5 KXS94563.1 - 0.37 10.9 10.9 3.7 7.6 9.5 2.6 1 1 1 2 2 2 0 Spermatogenesis-associated C-terminus DUF4407 PF14362.6 KXS94563.1 - 0.43 9.9 12.3 0.035 13.5 4.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) YlqD PF11068.8 KXS94563.1 - 0.77 10.1 8.8 0.65 10.4 5.0 2.2 2 0 0 2 2 2 0 YlqD protein FliD_N PF02465.18 KXS94563.1 - 0.85 10.3 3.4 34 5.2 0.6 2.7 1 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus SKA2 PF16740.5 KXS94563.1 - 3.4 7.5 11.2 3.2 7.6 2.5 3.2 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 FTA4 PF13093.6 KXS94563.1 - 3.6 7.4 13.5 36 4.2 12.9 2.2 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF4349 PF14257.6 KXS94563.1 - 4 6.8 14.7 5.3 6.4 2.9 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4349) CPSase_L_D3 PF02787.19 KXS94563.1 - 7 7.0 5.9 49 4.3 0.3 3.3 1 1 2 3 3 3 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CEP209_CC5 PF16574.5 KXS94564.1 - 0.059 13.5 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Coiled-coil region of centrosome protein CE290 DEAD PF00270.29 KXS94565.1 - 3.7e-39 134.3 0.6 5.6e-39 133.7 0.6 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXS94565.1 - 1.5e-31 109.0 0.6 8.3e-31 106.6 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXS94565.1 - 5.2e-08 33.1 0.0 1.2e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KXS94565.1 - 0.083 12.2 0.1 0.083 12.2 0.1 3.0 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit CCDC-167 PF15188.6 KXS94565.1 - 6.9 7.1 7.0 3.3 8.1 1.4 2.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Cwf_Cwc_15 PF04889.12 KXS94566.1 - 3.5e-83 279.1 26.8 4.2e-83 278.9 26.8 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SAPS PF04499.15 KXS94566.1 - 7.6 5.2 12.8 11 4.7 12.8 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF3131 PF11329.8 KXS94569.1 - 0.077 12.1 0.1 0.86 8.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3131) RNase_PH PF01138.21 KXS94572.1 - 1.1e-23 84.1 0.1 2.6e-23 83.0 0.0 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KXS94572.1 - 3.8e-06 26.8 0.0 8.1e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 RT_RNaseH_2 PF17919.1 KXS94572.1 - 0.15 12.1 0.1 0.69 10.0 0.0 2.0 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase GA PF01468.17 KXS94573.1 - 7.4 6.9 14.7 1.7 9.0 0.7 4.4 4 0 0 4 4 4 0 GA module DnaJ PF00226.31 KXS94576.1 - 1.4e-21 76.3 2.8 2.6e-21 75.5 1.6 2.1 2 0 0 2 2 2 1 DnaJ domain DUF2956 PF11169.8 KXS94576.1 - 0.87 9.8 11.6 1.4 9.1 9.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) Sds3 PF08598.11 KXS94576.1 - 2 8.4 11.9 0.3 11.1 4.3 2.5 2 1 1 3 3 3 0 Sds3-like Acetyltransf_16 PF05301.11 KXS94577.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase, Mec-17 Aldedh PF00171.22 KXS94583.1 - 5.8e-159 529.5 0.0 6.5e-159 529.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KXS94583.1 - 0.0008 18.9 0.0 0.0072 15.8 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) FMO-like PF00743.19 KXS94584.1 - 9.9e-12 44.0 0.0 4.1e-07 28.8 0.0 2.6 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KXS94584.1 - 8e-11 42.0 0.0 2.2e-10 40.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXS94584.1 - 7.8e-07 28.6 0.0 0.0049 16.1 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXS94584.1 - 4.4e-05 22.8 0.0 0.76 8.9 0.0 3.4 3 1 0 4 4 4 3 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KXS94584.1 - 9.6e-05 22.1 0.0 0.42 10.1 0.0 2.8 1 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXS94584.1 - 0.00098 18.5 0.0 0.024 13.9 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXS94584.1 - 0.0052 16.8 0.0 0.024 14.6 0.0 2.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 KXS94584.1 - 0.0057 15.9 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 KXS94584.1 - 0.075 11.7 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Fungal_trans PF04082.18 KXS94585.1 - 1e-19 70.6 0.0 1.9e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS94585.1 - 6.9e-05 22.9 7.2 0.00012 22.1 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_23 PF13489.6 KXS94587.1 - 4.9e-24 85.0 0.0 1e-23 84.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS94587.1 - 4.4e-07 30.5 0.0 1.2e-06 29.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS94587.1 - 9.5e-05 23.1 0.0 0.0004 21.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS94587.1 - 0.0001 22.2 0.0 0.00019 21.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS94587.1 - 0.00039 21.0 0.0 0.0011 19.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Pox_MCEL PF03291.16 KXS94587.1 - 0.032 13.3 0.0 0.063 12.4 0.0 1.4 1 0 0 1 1 1 0 mRNA capping enzyme Ubie_methyltran PF01209.18 KXS94587.1 - 0.17 11.2 0.0 0.27 10.6 0.0 1.3 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family EthD PF07110.11 KXS94588.1 - 2.7e-18 66.9 0.4 3.6e-18 66.5 0.4 1.2 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 KXS94588.1 - 2.8e-08 34.2 0.1 3.9e-08 33.8 0.1 1.2 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase TRI12 PF06609.13 KXS94590.1 - 1.8e-23 82.9 10.5 2e-23 82.7 10.5 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KXS94590.1 - 1.7e-13 50.2 26.9 4.1e-13 49.0 26.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS94590.1 - 1.2e-07 31.0 12.3 2.7e-07 29.8 12.3 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter DAO PF01266.24 KXS94591.1 - 2.1e-45 155.8 0.1 2.5e-45 155.6 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXS94591.1 - 2.7e-06 26.8 0.0 0.00013 21.3 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXS94591.1 - 6.2e-06 26.3 0.1 0.14 12.1 0.1 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KXS94591.1 - 3.4e-05 24.0 0.0 7.5e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KXS94591.1 - 0.00052 19.2 0.1 0.002 17.3 0.0 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 KXS94591.1 - 0.0013 18.1 0.0 0.042 13.1 0.0 2.1 2 0 0 2 2 2 1 Thi4 family Sacchrp_dh_NADP PF03435.18 KXS94591.1 - 0.016 15.4 0.0 0.033 14.4 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Trp_halogenase PF04820.14 KXS94591.1 - 0.017 14.0 0.0 0.93 8.3 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase FAD_binding_2 PF00890.24 KXS94591.1 - 0.021 13.9 0.1 4.9 6.1 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 KXS94591.1 - 0.18 12.4 0.2 2 9.1 0.0 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.25 KXS94592.1 - 5.1e-32 110.9 0.0 7.1e-32 110.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS94592.1 - 5e-25 88.4 0.0 6.8e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS94592.1 - 5.7e-05 23.1 0.0 0.0001 22.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS94592.1 - 0.018 14.5 0.1 0.033 13.7 0.1 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KXS94592.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FMO-like PF00743.19 KXS94593.1 - 4.7e-17 61.6 1.1 2.2e-14 52.8 0.2 2.3 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KXS94593.1 - 9.8e-12 44.9 0.0 2.5e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KXS94593.1 - 2.8e-06 26.7 0.0 0.0073 15.5 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KXS94593.1 - 8.5e-06 25.8 0.0 0.00013 22.0 0.0 2.5 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KXS94593.1 - 4.6e-05 22.8 0.0 0.0019 17.5 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXS94593.1 - 9.9e-05 21.7 0.0 0.004 16.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXS94593.1 - 0.005 16.5 0.0 0.23 11.0 0.0 2.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase Arc_PepC_II PF06847.11 KXS94593.1 - 0.25 11.9 0.9 0.8 10.3 0.9 1.8 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminus Type II mRNA_cap_C PF03919.15 KXS94593.1 - 0.31 11.7 4.6 0.19 12.4 0.3 2.5 2 0 0 2 2 2 0 mRNA capping enzyme, C-terminal domain TRI12 PF06609.13 KXS94594.1 - 1.9e-08 33.2 0.2 2e-08 33.1 0.2 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ADH_zinc_N PF00107.26 KXS94595.1 - 1.1e-22 80.4 0.1 2.1e-22 79.5 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXS94595.1 - 2.7e-17 62.6 4.3 6.6e-17 61.4 4.3 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 KXS94595.1 - 0.00043 19.7 0.3 0.00043 19.7 0.3 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KXS94595.1 - 0.0012 18.3 0.1 0.0025 17.2 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KXS94595.1 - 0.0032 17.4 0.4 0.0058 16.5 0.4 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 KXS94595.1 - 0.028 14.7 0.1 0.064 13.5 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain PglD_N PF17836.1 KXS94595.1 - 0.055 14.1 0.1 0.11 13.1 0.1 1.6 1 0 0 1 1 1 0 PglD N-terminal domain Methyltransf_25 PF13649.6 KXS94595.1 - 0.079 13.7 0.1 0.25 12.1 0.1 1.9 1 0 0 1 1 1 0 Methyltransferase domain DrsE PF02635.15 KXS94595.1 - 0.11 12.8 1.1 0.19 12.1 0.3 1.7 2 0 0 2 2 2 0 DsrE/DsrF-like family adh_short_C2 PF13561.6 KXS94596.1 - 1.3e-55 188.5 0.1 1.6e-55 188.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS94596.1 - 1.6e-45 155.0 0.1 2.1e-45 154.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS94596.1 - 1.1e-11 45.0 0.1 1.5e-11 44.5 0.1 1.2 1 0 0 1 1 1 1 KR domain Methyltransf_25 PF13649.6 KXS94596.1 - 0.0056 17.4 0.0 0.01 16.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Polysacc_synt_2 PF02719.15 KXS94596.1 - 0.0079 15.4 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein ThiF PF00899.21 KXS94596.1 - 0.011 15.0 0.7 0.027 13.8 0.7 1.8 1 1 0 1 1 1 0 ThiF family Methyltransf_12 PF08242.12 KXS94596.1 - 0.015 16.0 0.1 0.024 15.4 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ldh_1_N PF00056.23 KXS94596.1 - 0.016 15.3 0.0 0.034 14.2 0.0 1.6 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain MTS PF05175.14 KXS94596.1 - 0.025 14.1 0.1 0.045 13.3 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Epimerase PF01370.21 KXS94596.1 - 0.027 13.9 0.2 0.038 13.4 0.2 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KXS94596.1 - 0.052 13.8 0.1 0.095 13.0 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DOT1 PF08123.13 KXS94596.1 - 0.082 12.4 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 Fungal_TACC PF12709.7 KXS94597.1 - 3.4e-07 30.6 3.9 3.4e-07 30.6 3.9 4.2 4 0 0 4 4 4 3 Fungal Transforming acidic coiled-coil (TACC) proteins BTB PF00651.31 KXS94600.1 - 2.7e-08 34.0 0.0 4e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF5018 PF16410.5 KXS94600.1 - 0.007 15.1 0.0 0.0086 14.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5018) ATG101 PF07855.12 KXS94601.1 - 2e-50 170.8 0.2 2.3e-50 170.6 0.2 1.0 1 0 0 1 1 1 1 Autophagy-related protein 101 Brix PF04427.18 KXS94602.1 - 1.1e-38 133.3 0.0 1.4e-38 132.9 0.0 1.2 1 0 0 1 1 1 1 Brix domain HET PF06985.11 KXS94603.1 - 3e-29 102.2 1.6 6e-25 88.3 0.2 2.5 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) NAD_binding_4 PF07993.12 KXS94604.1 - 4.8e-39 134.1 0.0 8.2e-39 133.3 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KXS94604.1 - 2.5e-23 82.4 0.0 3.8e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KXS94604.1 - 2.1e-11 43.7 0.0 3.6e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXS94604.1 - 6.7e-05 22.4 0.0 0.00011 21.7 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 KXS94604.1 - 0.0007 19.6 0.3 0.0023 17.9 0.3 1.9 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXS94604.1 - 0.0018 17.5 0.0 0.018 14.2 0.0 2.3 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein PP-binding PF00550.25 KXS94604.1 - 0.0026 18.1 0.0 0.0082 16.5 0.0 1.9 2 0 0 2 2 2 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 KXS94604.1 - 0.036 13.1 0.0 0.12 11.4 0.0 1.8 2 1 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family GH3 PF03321.13 KXS94604.1 - 0.12 11.2 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 GH3 auxin-responsive promoter DUF1593 PF07632.11 KXS94605.1 - 8.2e-92 307.3 0.0 1.2e-91 306.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) Peptidase_M28 PF04389.17 KXS94606.1 - 5.1e-28 98.1 0.2 2.6e-27 95.8 0.2 1.9 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KXS94606.1 - 3.2e-06 27.0 0.1 5.1e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 KXS94606.1 - 0.15 11.1 0.1 0.45 9.5 0.1 1.7 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase G6PD_C PF02781.16 KXS94607.1 - 8.5e-114 379.6 0.0 2.3e-113 378.2 0.0 1.6 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KXS94607.1 - 1.6e-62 211.2 0.1 3.4e-62 210.2 0.1 1.5 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain ArAE_1_C PF11728.8 KXS94607.1 - 0.0062 16.5 0.3 0.016 15.2 0.3 1.6 1 0 0 1 1 1 1 Putative aromatic acid exporter C-terminal domain SNF2_N PF00176.23 KXS94608.1 - 5.2e-65 219.4 1.1 5.2e-65 219.4 1.1 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.6 KXS94608.1 - 7.7e-45 152.5 19.0 7.7e-45 152.5 19.0 5.3 5 1 1 6 6 6 1 DNA-binding domain Helicase_C PF00271.31 KXS94608.1 - 6.1e-19 68.4 0.0 1.8e-18 66.9 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXS94608.1 - 1.1e-05 25.5 0.0 1.1e-05 25.5 0.0 3.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KXS94608.1 - 0.0029 17.4 0.0 0.008 16.0 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Pneumo_att_G PF05539.11 KXS94608.1 - 0.27 10.8 0.0 0.27 10.8 0.0 3.3 2 1 1 3 3 3 0 Pneumovirinae attachment membrane glycoprotein G DUF29 PF01724.16 KXS94609.1 - 0.021 15.1 2.9 0.034 14.4 2.3 1.7 1 1 0 1 1 1 0 Domain of unknown function DUF29 DUF4477 PF14780.6 KXS94609.1 - 0.087 12.4 1.1 0.2 11.3 0.9 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4477) HET PF06985.11 KXS94610.1 - 2.1e-12 47.6 0.1 4.3e-12 46.6 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ribosomal_L35Ae PF01247.18 KXS94611.1 - 5e-41 138.8 0.6 5.8e-41 138.6 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 KXS94611.1 - 0.02 15.1 0.1 5.5 7.3 0.0 2.2 2 0 0 2 2 2 0 RimM N-terminal domain Mg_trans_NIPA PF05653.14 KXS94612.1 - 1.2e-59 201.9 7.5 8.7e-56 189.2 7.1 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 KXS94612.1 - 0.0018 18.5 0.8 0.0018 18.5 0.8 3.5 3 1 0 3 3 3 1 EamA-like transporter family DHHW PF14286.6 KXS94612.1 - 0.47 9.7 1.5 0.77 9.0 1.5 1.2 1 0 0 1 1 1 0 DHHW protein Tetraspanin PF00335.20 KXS94612.1 - 1.4 8.6 4.1 23 4.6 0.0 3.3 2 1 1 3 3 3 0 Tetraspanin family Presenilin PF01080.17 KXS94612.1 - 2.9 6.6 8.6 0.81 8.4 0.2 2.6 2 0 0 2 2 2 0 Presenilin Aldo_ket_red PF00248.21 KXS94613.1 - 6.9e-51 173.2 0.0 8.3e-51 172.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GTP_EFTU PF00009.27 KXS94614.1 - 6.1e-58 195.6 0.2 8.6e-58 195.1 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KXS94614.1 - 3.9e-27 94.8 0.0 9.4e-27 93.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KXS94614.1 - 4.1e-18 65.5 1.2 1.1e-17 64.1 1.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KXS94614.1 - 6.9e-06 26.1 0.0 1.6e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 KXS94614.1 - 0.0023 17.7 0.2 1.4 8.7 0.0 2.3 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 KXS94614.1 - 0.0033 17.4 0.2 0.065 13.1 0.1 2.2 1 1 0 2 2 2 1 RsgA GTPase cobW PF02492.19 KXS94614.1 - 0.012 15.2 0.3 0.11 12.0 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SWIRM PF04433.17 KXS94615.1 - 6.6e-32 109.7 0.1 1.9e-31 108.3 0.1 1.8 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 KXS94615.1 - 7.1e-27 93.2 14.5 7.1e-27 93.2 14.5 1.8 2 0 0 2 2 2 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 KXS94615.1 - 4.5e-09 36.3 0.0 8.4e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXS94615.1 - 0.00044 20.5 0.0 0.00099 19.3 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 KXS94615.1 - 0.016 15.0 6.8 0.86 9.5 0.2 2.3 2 0 0 2 2 2 0 Zinc finger, ZZ type Palm_thioest PF02089.15 KXS94616.1 - 1.2e-73 247.9 0.0 1.4e-73 247.7 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_2 PF01674.18 KXS94616.1 - 0.053 13.0 0.0 0.32 10.5 0.0 2.0 1 1 0 1 1 1 0 Lipase (class 2) SNF2_N PF00176.23 KXS94617.1 - 1.8e-76 257.1 0.1 3.1e-76 256.4 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXS94617.1 - 1.3e-12 48.0 0.0 8.9e-12 45.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXS94617.1 - 0.00015 21.6 0.0 0.00048 19.9 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KXS94617.1 - 0.0016 18.5 0.0 0.0049 16.9 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_5 PF14634.6 KXS94617.1 - 0.13 12.2 2.9 0.41 10.7 2.9 1.9 1 1 0 1 1 1 0 zinc-RING finger domain ubiquitin PF00240.23 KXS94618.1 - 6.9e-34 115.4 0.6 9.5e-34 115.0 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 KXS94618.1 - 8.9e-32 108.8 12.1 1.8e-31 107.7 12.1 1.6 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 KXS94618.1 - 3.8e-16 58.7 0.7 5.8e-16 58.1 0.7 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KXS94618.1 - 3.5e-05 24.2 0.2 0.00013 22.4 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 KXS94618.1 - 0.0026 18.1 0.2 0.0041 17.4 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KXS94618.1 - 0.0044 16.9 0.1 0.007 16.3 0.1 1.4 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KXS94618.1 - 0.011 15.9 0.1 0.024 14.7 0.1 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KXS94618.1 - 0.022 15.3 0.1 0.068 13.7 0.0 1.8 1 1 1 2 2 2 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 KXS94618.1 - 0.031 14.3 1.0 6.6 6.8 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain SpoU_methylase PF00588.19 KXS94619.1 - 1.5e-24 86.8 0.0 3.8e-24 85.5 0.0 1.8 1 0 0 1 1 1 1 SpoU rRNA Methylase family ECH_2 PF16113.5 KXS94620.1 - 9.1e-123 410.0 0.0 1.1e-122 409.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 KXS94620.1 - 3.3e-27 95.4 0.0 7.3e-27 94.3 0.0 1.5 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase Meth_synt_2 PF01717.18 KXS94621.1 - 8.2e-10 38.5 0.0 3.2e-06 26.7 0.0 2.5 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Phage_Orf51 PF06194.11 KXS94621.1 - 0.0015 18.5 0.0 0.0045 17.0 0.0 1.8 1 1 0 1 1 1 1 Phage Conserved Open Reading Frame 51 Meth_synt_1 PF08267.12 KXS94621.1 - 0.027 14.0 0.1 0.081 12.4 0.1 1.8 2 0 0 2 2 2 0 Cobalamin-independent synthase, N-terminal domain Amidase PF01425.21 KXS94621.1 - 0.041 12.8 0.0 0.082 11.8 0.0 1.4 2 0 0 2 2 2 0 Amidase Ribosomal_L38e PF01781.18 KXS94622.1 - 0.0052 16.8 0.6 0.79 9.9 0.0 3.8 3 0 0 3 3 3 1 Ribosomal L38e protein family Orthopox_B11R PF07033.11 KXS94622.1 - 0.011 15.5 0.0 0.029 14.2 0.0 1.8 1 0 0 1 1 1 0 Orthopoxvirus B11R protein LTV PF04180.14 KXS94625.1 - 2e-125 419.5 11.8 2.3e-125 419.3 11.8 1.0 1 0 0 1 1 1 1 Low temperature viability protein COX16 PF14138.6 KXS94625.1 - 0.49 10.9 0.0 0.49 10.9 0.0 2.6 3 0 0 3 3 3 0 Cytochrome c oxidase assembly protein COX16 DUF1295 PF06966.12 KXS94626.1 - 1.1e-17 64.4 1.1 1.3e-17 64.1 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 KXS94626.1 - 0.00074 19.5 1.9 0.00095 19.2 1.7 1.3 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ERG4_ERG24 PF01222.17 KXS94626.1 - 0.0021 16.9 9.0 0.01 14.7 9.0 1.9 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family F-box PF00646.33 KXS94627.1 - 0.0057 16.5 0.1 0.012 15.4 0.1 1.6 1 0 0 1 1 1 1 F-box domain FAD_binding_3 PF01494.19 KXS94630.1 - 3.3e-77 260.1 0.0 4.2e-77 259.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXS94630.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.25 KXS94631.1 - 5.8e-29 101.0 0.0 3.3e-24 85.5 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXS94631.1 - 9.2e-17 61.4 0.1 1.3e-14 54.3 0.1 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS94631.1 - 0.00018 21.5 0.1 0.00034 20.6 0.1 1.4 1 0 0 1 1 1 1 KR domain MT0933_antitox PF14013.6 KXS94631.1 - 2.9 8.3 7.1 0.38 11.1 1.6 2.4 4 0 0 4 4 4 0 MT0933-like antitoxin protein ABC_tran PF00005.27 KXS94632.1 - 8.4e-47 159.1 0.1 1.2e-22 80.9 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 KXS94632.1 - 8.5e-23 80.2 6.2 8.5e-23 80.2 6.2 2.6 3 0 0 3 3 2 1 ABC transporter AAA_21 PF13304.6 KXS94632.1 - 5.7e-18 65.8 0.5 0.0004 20.3 0.0 4.7 3 1 2 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXS94632.1 - 1.4e-09 37.7 0.4 0.37 10.2 0.0 4.4 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KXS94632.1 - 1e-08 35.9 3.6 0.035 14.6 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 KXS94632.1 - 9.7e-08 31.6 0.2 0.0039 16.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 KXS94632.1 - 1.6e-07 31.4 0.1 0.018 14.8 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 KXS94632.1 - 1.2e-06 28.6 0.7 0.001 19.0 0.1 2.9 3 0 0 3 3 3 1 RsgA GTPase AAA_16 PF13191.6 KXS94632.1 - 1.5e-06 28.7 0.0 0.046 14.1 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 KXS94632.1 - 4.3e-06 27.3 1.0 0.12 12.9 0.0 3.7 4 0 0 4 4 4 2 AAA domain AAA_22 PF13401.6 KXS94632.1 - 8.9e-05 22.8 0.0 0.21 11.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 KXS94632.1 - 9.3e-05 22.9 0.0 0.76 10.2 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 KXS94632.1 - 0.00012 22.2 0.0 0.082 13.0 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase NACHT PF05729.12 KXS94632.1 - 0.00019 21.4 0.1 0.7 9.8 0.0 2.6 2 0 0 2 2 2 2 NACHT domain RNA_helicase PF00910.22 KXS94632.1 - 0.00019 21.7 1.1 0.83 10.1 0.0 3.3 3 0 0 3 3 3 2 RNA helicase AAA_5 PF07728.14 KXS94632.1 - 0.00035 20.6 0.2 0.91 9.5 0.0 2.8 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KXS94632.1 - 0.00038 20.6 0.0 2.3 8.4 0.0 3.2 3 0 0 3 3 3 2 AAA domain Roc PF08477.13 KXS94632.1 - 0.00094 19.4 0.0 2 8.6 0.0 2.8 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 KXS94632.1 - 0.0011 18.2 0.9 3 6.9 0.0 3.5 3 1 0 3 3 3 2 NB-ARC domain AAA_14 PF13173.6 KXS94632.1 - 0.002 18.1 0.0 2.4 8.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KXS94632.1 - 0.0025 18.1 0.1 0.81 9.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_27 PF13514.6 KXS94632.1 - 0.0032 17.1 1.1 1.4 8.4 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_24 PF13479.6 KXS94632.1 - 0.0036 17.0 0.7 1.7 8.3 0.0 3.0 3 0 0 3 3 3 1 AAA domain Phage_tail_2 PF06199.11 KXS94632.1 - 0.0045 17.1 0.0 0.012 15.7 0.0 1.7 1 0 0 1 1 1 1 Phage tail tube protein AAA_7 PF12775.7 KXS94632.1 - 0.0047 16.5 0.4 1.5 8.3 0.0 2.8 3 0 0 3 3 3 1 P-loop containing dynein motor region Rad17 PF03215.15 KXS94632.1 - 0.0049 16.8 0.2 2.1 8.2 0.0 2.7 3 0 0 3 3 3 1 Rad17 P-loop domain Ras PF00071.22 KXS94632.1 - 0.016 14.8 0.2 7.9 6.0 0.0 2.6 3 0 0 3 3 3 0 Ras family ATP-synt_ab PF00006.25 KXS94632.1 - 0.022 14.4 0.0 0.1 12.3 0.0 2.1 2 1 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.6 KXS94632.1 - 0.039 13.5 0.0 1.7 8.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 KXS94632.1 - 0.044 13.5 3.4 7.5 6.2 0.1 3.6 3 1 0 3 3 3 0 AAA domain ATPase_2 PF01637.18 KXS94632.1 - 0.072 13.0 1.3 15 5.4 0.1 3.1 3 1 1 4 4 4 0 ATPase domain predominantly from Archaea Dynamin_N PF00350.23 KXS94632.1 - 0.078 13.0 2.9 10 6.2 0.0 3.6 2 1 1 3 3 3 0 Dynamin family MCM PF00493.23 KXS94632.1 - 0.11 11.6 0.1 7.3 5.6 0.0 2.3 2 0 0 2 2 2 0 MCM P-loop domain AAA_17 PF13207.6 KXS94632.1 - 0.16 12.4 2.3 11 6.5 0.0 3.5 4 0 0 4 4 4 0 AAA domain Cupin_1 PF00190.22 KXS94634.1 - 1e-15 57.6 0.0 1.9e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 KXS94634.1 - 0.0075 16.0 0.1 0.5 10.1 0.1 2.3 2 0 0 2 2 2 2 Cupin domain FA_hydroxylase PF04116.13 KXS94635.1 - 6.1e-25 88.1 15.6 6.1e-25 88.1 15.6 2.6 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily UL41A PF17591.2 KXS94635.1 - 0.047 13.8 2.2 0.12 12.5 2.2 1.6 1 0 0 1 1 1 0 Herpesvirus UL41A Rota_VP4_MID PF17477.2 KXS94635.1 - 0.065 12.6 0.4 0.21 10.9 0.7 1.7 2 0 0 2 2 2 0 Rotavirus VP4 membrane interaction domain DUF1752 PF08550.10 KXS94637.1 - 3.1e-08 33.3 4.8 8.2e-08 31.9 4.8 1.8 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) MMR_HSR1 PF01926.23 KXS94638.1 - 2e-16 60.1 0.1 7.5e-15 55.0 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXS94638.1 - 1.2e-06 28.1 0.2 4.8e-05 22.9 0.1 2.5 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KXS94638.1 - 2.2e-05 24.4 0.0 0.0099 15.8 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 KXS94638.1 - 0.015 14.6 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 AIG1 family SDA1 PF05285.12 KXS94638.1 - 0.21 11.0 14.9 0.43 10.0 14.9 1.5 1 0 0 1 1 1 0 SDA1 DUF572 PF04502.13 KXS94638.1 - 0.4 10.3 9.5 0.059 13.0 5.4 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF572) Dynamin_N PF00350.23 KXS94638.1 - 1 9.4 5.2 0.19 11.8 0.2 2.3 2 1 0 2 2 2 0 Dynamin family Abhydrolase_6 PF12697.7 KXS94639.1 - 3.2e-10 41.0 0.9 5.3e-10 40.3 0.9 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXS94639.1 - 2.4e-08 33.6 0.0 3.9e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXS94639.1 - 0.0039 16.9 0.1 0.0069 16.1 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXS94640.1 - 3.2e-10 41.0 0.9 5.3e-10 40.3 0.9 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXS94640.1 - 2.4e-08 33.6 0.0 3.9e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXS94640.1 - 0.0039 16.9 0.1 0.0069 16.1 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXS94641.1 - 3.2e-10 41.0 0.9 5.3e-10 40.3 0.9 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXS94641.1 - 2.4e-08 33.6 0.0 3.9e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXS94641.1 - 0.0039 16.9 0.1 0.0069 16.1 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXS94642.1 - 3.2e-10 41.0 0.9 5.3e-10 40.3 0.9 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXS94642.1 - 2.4e-08 33.6 0.0 3.9e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXS94642.1 - 0.0039 16.9 0.1 0.0069 16.1 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Fungal_trans_2 PF11951.8 KXS94643.1 - 7.4e-16 57.9 3.9 1.1e-08 34.3 0.2 2.5 2 1 1 3 3 3 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS94643.1 - 6.8e-10 38.9 14.7 1.1e-09 38.2 14.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain eIF3m_C_helix PF18005.1 KXS94643.1 - 0.37 10.5 3.3 0.76 9.5 3.3 1.5 1 0 0 1 1 1 0 eIF3 subunit M, C-terminal helix Abhydrolase_6 PF12697.7 KXS94644.1 - 3.2e-10 41.0 0.9 5.3e-10 40.3 0.9 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXS94644.1 - 2.4e-08 33.6 0.0 3.9e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXS94644.1 - 0.0039 16.9 0.1 0.0069 16.1 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold ELMO_CED12 PF04727.13 KXS94645.1 - 1.5e-40 139.2 0.0 2.6e-40 138.4 0.0 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family PH_12 PF16457.5 KXS94645.1 - 7.3e-33 113.9 0.4 1.5e-32 112.9 0.4 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain DUF3361 PF11841.8 KXS94645.1 - 3.5e-10 40.0 0.0 8e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) ZFYVE21_C PF16696.5 KXS94645.1 - 0.027 14.3 0.0 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 Zinc finger FYVE domain-containing protein 21 C-terminus PerC PF06069.11 KXS94645.1 - 0.093 13.0 0.0 0.48 10.7 0.0 2.2 2 0 0 2 2 2 0 PerC transcriptional activator SURF2 PF05477.11 KXS94645.1 - 0.38 10.4 0.0 0.38 10.4 0.0 1.7 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) RRM_1 PF00076.22 KXS94648.1 - 1e-42 143.8 1.5 3.1e-12 46.1 0.1 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXS94648.1 - 8.1e-21 73.7 0.1 2.4e-16 59.3 0.0 3.8 3 1 1 4 4 4 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KXS94648.1 - 1.8e-08 34.2 0.0 0.045 13.8 0.0 4.2 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif TPR_14 PF13428.6 KXS94648.1 - 6 8.0 16.0 9.5 7.3 0.2 6.0 5 2 2 7 7 7 0 Tetratricopeptide repeat Glyco_hydro_125 PF06824.11 KXS94651.1 - 5.6e-169 562.4 0.3 6.7e-169 562.2 0.3 1.1 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) Dicty_CAR PF05462.11 KXS94652.1 - 2.9e-11 43.0 0.8 2.3e-06 27.0 0.4 2.1 2 0 0 2 2 2 2 Slime mold cyclic AMP receptor Git3 PF11710.8 KXS94652.1 - 3.8e-08 33.3 4.7 9e-08 32.1 4.7 1.6 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 KXS94652.1 - 0.00021 21.3 0.0 0.00075 19.5 0.0 2.0 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.21 KXS94652.1 - 0.00042 19.7 0.0 0.00054 19.4 0.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) RicinB_lectin_2 PF14200.6 KXS94653.1 - 8.8e-08 32.8 0.9 0.00087 20.0 0.0 2.4 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like DUF3552 PF12072.8 KXS94653.1 - 1.6 8.1 57.3 0.22 10.9 11.3 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF3552) UPF0565 PF10561.9 KXS94653.1 - 9.8 5.3 10.4 24 4.0 10.4 1.6 1 1 0 1 1 1 0 Uncharacterised protein family UPF0565 Ribosomal_L22 PF00237.19 KXS94654.1 - 1e-25 89.9 0.1 9.6e-25 86.8 0.1 2.1 1 1 0 1 1 1 1 Ribosomal protein L22p/L17e BSP_II PF05432.11 KXS94654.1 - 0.021 14.6 1.6 0.043 13.5 1.6 1.5 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) COesterase PF00135.28 KXS94656.1 - 2.4e-58 198.3 0.0 6.5e-58 196.8 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXS94656.1 - 0.0017 18.2 0.0 2 8.2 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 KXS94657.1 - 2.8e-58 198.1 0.0 7.5e-58 196.6 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXS94657.1 - 0.0019 18.1 0.0 2.1 8.1 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 KXS94658.1 - 2.4e-58 198.3 0.0 6.5e-58 196.8 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXS94658.1 - 0.0017 18.2 0.0 2 8.2 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold zf-C2H2_12 PF18658.1 KXS94659.1 - 0.16 11.5 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Zinc-finger C2H2-type BpuSI_N PF15516.6 KXS94662.1 - 0.16 11.8 0.0 0.25 11.3 0.0 1.2 1 0 0 1 1 1 0 BpuSI N-terminal domain IBN_N PF03810.19 KXS94663.1 - 1.5e-13 50.5 0.3 1.4e-12 47.3 0.0 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KXS94663.1 - 0.0012 18.9 3.6 0.0036 17.4 0.1 3.5 4 1 1 5 5 5 1 Exportin 1-like protein DUF3385 PF11865.8 KXS94663.1 - 0.053 13.4 0.6 0.33 10.9 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) Peptidase_C48 PF02902.19 KXS94664.1 - 1.1e-05 25.3 1.3 1.5e-05 25.0 0.1 1.7 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain Ribosomal_L37e PF01907.19 KXS94665.1 - 3.7e-26 91.0 11.1 5.4e-26 90.5 11.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 KXS94665.1 - 0.0094 16.0 1.0 0.014 15.4 1.0 1.2 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.19 KXS94665.1 - 0.035 14.1 0.7 0.047 13.7 0.7 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_2 PF13240.6 KXS94665.1 - 0.1 12.4 2.1 4.8 7.0 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-RING_10 PF16685.5 KXS94665.1 - 0.1 12.7 2.2 0.13 12.4 2.2 1.2 1 0 0 1 1 1 0 zinc RING finger of MSL2 zinc_ribbon_6 PF14599.6 KXS94665.1 - 0.33 11.0 3.3 0.54 10.3 3.3 1.3 1 0 0 1 1 1 0 Zinc-ribbon RRM_1 PF00076.22 KXS94666.1 - 1.3e-07 31.3 0.0 2.2e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KXS94666.1 - 3.7e-07 30.0 0.0 6.1e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KXS94666.1 - 0.0041 17.0 0.1 0.015 15.1 0.0 2.1 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_3 PF08777.11 KXS94666.1 - 0.0093 16.0 0.0 0.022 14.8 0.0 1.6 1 0 0 1 1 1 1 RNA binding motif Pro-kuma_activ PF09286.11 KXS94667.1 - 2.4e-15 57.1 0.1 1.2e-14 54.9 0.0 2.1 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KXS94667.1 - 5.5e-05 22.6 0.1 9.3e-05 21.8 0.1 1.3 1 0 0 1 1 1 1 Subtilase family PPR_2 PF13041.6 KXS94668.1 - 1.3e-14 54.1 4.2 7.3e-06 26.1 0.2 6.3 7 0 0 7 7 7 3 PPR repeat family PPR PF01535.20 KXS94668.1 - 9e-11 41.3 4.9 0.061 13.6 0.0 6.9 7 0 0 7 7 7 3 PPR repeat PPR_3 PF13812.6 KXS94668.1 - 3.9e-08 33.3 0.7 0.19 11.8 0.0 4.1 2 1 2 4 4 4 4 Pentatricopeptide repeat domain PPR_long PF17177.4 KXS94668.1 - 1.4e-07 31.1 0.4 0.00044 19.7 0.2 3.1 2 0 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP TPR_12 PF13424.6 KXS94668.1 - 0.00071 19.8 8.7 0.21 11.9 1.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXS94668.1 - 0.12 13.1 6.3 9.8 6.9 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXS94668.1 - 0.14 13.1 18.3 9.8 7.3 0.2 7.6 7 0 0 7 7 7 0 Tetratricopeptide repeat TetR_C_28 PF17937.1 KXS94668.1 - 0.67 10.4 5.8 0.77 10.3 0.0 3.8 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain TPR_19 PF14559.6 KXS94668.1 - 3.9 8.1 8.9 7 7.2 0.0 4.8 3 1 1 4 4 4 0 Tetratricopeptide repeat DnaJ PF00226.31 KXS94669.1 - 1.8e-09 37.5 0.0 5.1e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain Med25_SD1 PF11235.8 KXS94669.1 - 0.12 12.7 0.5 0.33 11.3 0.2 1.7 2 0 0 2 2 2 0 Mediator complex subunit 25 synapsin 1 ETRAMP PF09716.10 KXS94670.1 - 0.02 15.0 0.0 2.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Herpes_US9 PF06072.11 KXS94670.1 - 0.026 14.4 2.6 0.058 13.3 2.6 1.5 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Neurensin PF14927.6 KXS94670.1 - 0.12 12.0 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Neurensin Rhodanese PF00581.20 KXS94671.1 - 2.1e-18 66.8 0.0 2.7e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain RlmM_FDX PF18125.1 KXS94671.1 - 0.19 12.2 0.5 0.32 11.5 0.0 1.6 2 0 0 2 2 2 0 RlmM ferredoxin-like domain zf-RING_2 PF13639.6 KXS94673.1 - 4.1e-09 36.6 9.8 6.1e-09 36.1 9.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KXS94673.1 - 2.5e-06 27.2 4.4 4.4e-06 26.5 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXS94673.1 - 1.6e-05 24.8 7.1 2.5e-05 24.2 7.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KXS94673.1 - 6.9e-05 22.6 6.6 0.00018 21.3 6.9 1.5 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KXS94673.1 - 0.00026 20.8 8.6 0.0004 20.1 8.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS94673.1 - 0.00027 20.7 7.4 0.00044 20.1 7.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXS94673.1 - 0.00063 19.4 3.8 0.0011 18.6 3.8 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KXS94673.1 - 0.024 14.7 8.6 0.056 13.5 8.6 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.7 KXS94673.1 - 0.087 13.1 14.3 1.2 9.5 14.3 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain zinc_ribbon_11 PF11682.8 KXS94673.1 - 0.12 12.4 0.1 0.21 11.6 0.1 1.4 1 0 0 1 1 1 0 Probable zinc-ribbon zf-ANAPC11 PF12861.7 KXS94673.1 - 0.36 10.9 3.3 0.68 10.0 3.3 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KXS94673.1 - 1.5 8.7 7.4 4.7 7.1 7.5 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zinc_ribbon_10 PF10058.9 KXS94673.1 - 2.9 7.7 5.1 0.84 9.4 1.1 2.1 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-C3HC4_4 PF15227.6 KXS94673.1 - 3.3 8.0 7.1 9.5 6.5 7.3 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING IBR PF01485.21 KXS94673.1 - 9.6 6.5 10.0 46 4.3 10.0 2.0 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain AMP-binding PF00501.28 KXS94675.1 - 8.4e-30 103.7 0.0 6e-29 100.9 0.0 2.3 1 1 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 KXS94675.1 - 0.00038 20.8 0.0 0.00076 19.8 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Y_phosphatase3 PF13350.6 KXS94676.1 - 2.9e-52 178.0 0.0 7.3e-26 91.6 0.0 2.0 2 0 0 2 2 2 2 Tyrosine phosphatase family UQ_con PF00179.26 KXS94677.1 - 8.1e-19 67.7 0.0 1.2e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PEX11 PF05648.14 KXS94678.1 - 3.2e-09 36.6 4.6 3.6e-09 36.4 0.5 2.4 2 1 0 2 2 2 1 Peroxisomal biogenesis factor 11 (PEX11) T6SS-SciN PF12790.7 KXS94678.1 - 0.047 13.4 0.0 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 MutL_C PF08676.11 KXS94680.1 - 1.4e-27 96.2 0.0 3.3e-27 95.0 0.0 1.6 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 KXS94680.1 - 3.1e-21 75.2 0.1 5.3e-20 71.3 0.0 2.4 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KXS94680.1 - 4.7e-11 42.7 0.1 1.3e-10 41.2 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KXS94680.1 - 3.6e-08 33.9 0.0 8e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HK97-gp10_like PF04883.12 KXS94680.1 - 0.017 16.1 2.2 5.9 8.0 1.0 2.9 2 0 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component Lyase_aromatic PF00221.19 KXS94681.1 - 0.00028 19.7 0.0 0.00032 19.5 0.0 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase Lyase_aromatic PF00221.19 KXS94682.1 - 5.7e-150 500.0 3.3 7.4e-150 499.6 3.3 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase Frigida PF07899.11 KXS94682.1 - 0.011 15.0 0.3 0.02 14.2 0.3 1.4 1 0 0 1 1 1 0 Frigida-like protein DAO PF01266.24 KXS94683.1 - 6.5e-32 111.5 0.0 8.7e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXS94683.1 - 4.3e-06 26.2 0.0 0.037 13.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXS94683.1 - 5.4e-06 25.5 0.0 0.027 13.3 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_9 PF13454.6 KXS94683.1 - 6.7e-05 22.9 0.0 0.037 14.0 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KXS94683.1 - 0.00034 20.8 0.0 0.001 19.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 KXS94683.1 - 0.0059 16.9 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain GIDA PF01134.22 KXS94683.1 - 0.0068 15.5 0.1 0.068 12.2 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 KXS94683.1 - 0.021 15.4 0.0 0.4 11.3 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 KXS94683.1 - 0.16 12.2 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Glyco_transf_54 PF04666.13 KXS94684.1 - 4.5e-10 38.9 0.0 1.8e-08 33.6 0.0 2.7 2 1 0 2 2 2 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region FAT PF02259.23 KXS94685.1 - 6.5e-127 423.5 1.2 1.8e-126 422.1 1.2 1.8 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 KXS94685.1 - 4.9e-72 242.8 0.0 1.3e-71 241.3 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 KXS94685.1 - 2.1e-63 213.0 2.9 3.1e-58 196.2 0.0 5.9 5 1 1 6 6 6 2 Domain of unknown function (DUF3385) FRB_dom PF08771.11 KXS94685.1 - 9.6e-43 144.6 0.0 9.6e-43 144.6 0.0 4.3 4 0 0 4 4 3 1 FKBP12-rapamycin binding domain HEAT_2 PF13646.6 KXS94685.1 - 4.8e-16 58.9 17.5 0.0039 17.5 0.0 11.1 8 2 3 11 11 11 3 HEAT repeats FATC PF02260.20 KXS94685.1 - 4.1e-14 52.1 0.2 1.3e-13 50.5 0.2 2.0 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 KXS94685.1 - 5.4e-10 38.7 22.8 2.9 8.4 0.0 11.9 13 0 0 13 13 12 3 HEAT repeat HEAT_EZ PF13513.6 KXS94685.1 - 4e-09 36.8 12.0 0.28 11.7 0.0 11.2 11 2 1 12 12 11 2 HEAT-like repeat Cnd1 PF12717.7 KXS94685.1 - 1.9e-06 28.0 6.3 0.047 13.7 0.1 7.1 5 2 2 8 8 8 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KXS94685.1 - 3.4e-05 24.4 5.5 33 5.2 0.0 7.7 7 1 1 8 8 8 0 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 KXS94685.1 - 4.3e-05 22.3 8.1 0.073 11.6 2.4 5.8 4 2 1 5 5 5 1 Adaptin N terminal region ParcG PF10274.9 KXS94685.1 - 0.00024 21.3 5.4 0.86 9.7 0.1 5.3 5 0 0 5 5 5 1 Parkin co-regulated protein CLASP_N PF12348.8 KXS94685.1 - 0.00038 20.1 3.1 1.1 8.8 0.0 5.0 4 1 0 4 4 4 1 CLASP N terminal SesA PF17107.5 KXS94685.1 - 0.18 12.0 3.7 10 6.4 0.1 3.8 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases TPR_19 PF14559.6 KXS94685.1 - 2.6 8.6 5.3 3.1 8.4 0.1 4.0 5 0 0 5 5 3 0 Tetratricopeptide repeat Cut12 PF11500.8 KXS94686.1 - 0.18 11.8 0.6 0.31 11.0 0.6 1.3 1 0 0 1 1 1 0 Spindle pole body formation-associated protein Anophelin PF10731.9 KXS94686.1 - 1.1 9.2 3.9 3.3 7.6 3.9 1.8 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito ATP-synt_C PF00137.21 KXS94687.1 - 1.6e-26 92.4 14.4 3.9e-20 72.0 12.3 2.1 2 0 0 2 2 2 2 ATP synthase subunit C HA2 PF04408.23 KXS94688.1 - 2e-15 57.0 0.0 6.7e-15 55.3 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KXS94688.1 - 2.5e-14 53.6 0.0 6.7e-14 52.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KXS94688.1 - 3.6e-08 33.7 0.0 9.7e-08 32.3 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KXS94688.1 - 1.5e-07 31.4 0.1 3.3e-07 30.3 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 KXS94688.1 - 0.00021 21.6 0.6 0.033 14.5 0.0 4.0 4 1 0 4 4 4 1 AAA domain AAA_30 PF13604.6 KXS94688.1 - 0.045 13.5 0.0 0.27 10.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KXS94688.1 - 0.11 12.8 0.1 0.87 9.9 0.0 2.6 3 0 0 3 3 3 0 AAA domain dsrm PF00035.26 KXS94688.1 - 0.15 12.8 0.1 3 8.6 0.0 2.9 3 0 0 3 3 3 0 Double-stranded RNA binding motif Methyltransf_28 PF02636.17 KXS94689.1 - 5.5e-78 262.2 0.0 7e-78 261.9 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Ribosomal_L13 PF00572.18 KXS94690.1 - 1.3e-45 154.7 0.0 1.7e-45 154.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 DUF1137 PF06587.11 KXS94690.1 - 0.031 14.3 0.0 0.048 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1137) ILVD_EDD PF00920.21 KXS94692.1 - 5.9e-156 520.1 0.0 6.9e-156 519.9 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family Surp PF01805.20 KXS94693.1 - 2.8e-05 24.0 0.1 5.7e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 Surp module CTD_bind PF04818.13 KXS94693.1 - 7.9e-05 23.4 0.3 0.00026 21.7 0.3 2.0 1 1 0 1 1 1 1 RNA polymerase II-binding domain. ParE_toxin PF05016.15 KXS94693.1 - 0.46 11.1 1.7 2.5 8.8 0.0 3.0 3 0 0 3 3 3 0 ParE toxin of type II toxin-antitoxin system, parDE BCS1_N PF08740.11 KXS94694.1 - 1.1e-42 146.1 0.9 1.8e-42 145.4 0.9 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KXS94694.1 - 8.8e-20 71.5 0.0 1.6e-19 70.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXS94694.1 - 8.7e-05 22.5 0.0 0.00026 21.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXS94694.1 - 0.00019 21.9 0.1 0.00079 19.9 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 KXS94694.1 - 0.00061 19.6 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 KXS94694.1 - 0.00069 18.8 0.0 0.0016 17.6 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_25 PF13481.6 KXS94694.1 - 0.0044 16.6 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KXS94694.1 - 0.0064 16.0 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_18 PF13238.6 KXS94694.1 - 0.0065 17.0 0.1 0.031 14.8 0.0 2.2 2 1 0 2 2 2 1 AAA domain ATPase PF06745.13 KXS94694.1 - 0.0099 15.2 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_33 PF13671.6 KXS94694.1 - 0.016 15.3 0.0 0.074 13.2 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KXS94694.1 - 0.018 14.8 0.1 0.065 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KXS94694.1 - 0.035 14.5 0.0 0.11 12.9 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.6 KXS94694.1 - 0.051 13.8 0.1 0.19 12.0 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KXS94694.1 - 0.054 13.3 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KXS94694.1 - 0.094 13.0 0.0 0.39 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KXS94694.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KXS94694.1 - 0.17 11.8 0.1 0.94 9.4 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_17 PF13207.6 KXS94694.1 - 0.19 12.2 0.1 1.5 9.3 0.0 2.4 2 1 1 3 3 2 0 AAA domain Pkinase PF00069.25 KXS94696.1 - 7.4e-62 209.1 0.0 1.2e-61 208.4 0.0 1.4 2 0 0 2 2 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS94696.1 - 8.1e-27 94.1 0.0 1.2e-26 93.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXS94696.1 - 6.5e-05 22.4 0.1 0.00011 21.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KXS94696.1 - 0.00012 21.2 0.0 0.00018 20.6 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KXS94696.1 - 0.00013 21.4 0.1 0.0018 17.7 0.1 2.2 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KXS94696.1 - 0.12 12.0 0.0 0.12 12.0 0.0 1.6 2 0 0 2 2 2 0 RIO1 family Casc1_N PF15927.5 KXS94696.1 - 0.55 9.9 13.1 0.94 9.1 13.1 1.3 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus DUF4554 PF15091.6 KXS94696.1 - 2.5 6.9 5.2 3.6 6.4 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) CDC45 PF02724.14 KXS94696.1 - 2.6 6.3 8.8 3.6 5.8 8.8 1.1 1 0 0 1 1 1 0 CDC45-like protein NARP1 PF12569.8 KXS94696.1 - 4 6.2 9.2 5.5 5.8 9.2 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 APH PF01636.23 KXS94696.1 - 4.2 7.2 7.6 20 5.0 7.6 2.2 1 1 0 1 1 1 0 Phosphotransferase enzyme family Acetyltransf_1 PF00583.25 KXS94697.1 - 1.1e-09 38.6 0.0 1.5e-09 38.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXS94697.1 - 5.6e-09 36.3 0.0 1e-08 35.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXS94697.1 - 8.2e-09 35.5 0.0 1.4e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXS94697.1 - 1.2e-05 25.4 0.0 2.2e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXS94697.1 - 9e-05 22.4 0.0 0.00016 21.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KXS94697.1 - 0.0051 16.9 0.0 0.009 16.1 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase HET PF06985.11 KXS94698.1 - 5.8e-24 85.1 0.0 1.2e-23 84.0 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3176 PF11374.8 KXS94698.1 - 8.7e-12 45.2 1.9 2.2e-11 43.9 1.6 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3176) Uricase PF01014.18 KXS94699.1 - 1e-74 249.0 1.1 6.7e-39 133.1 0.6 2.2 2 0 0 2 2 2 2 Uricase RNA_pol_3_Rpc31 PF11705.8 KXS94700.1 - 2.3e-33 116.3 22.3 2.8e-33 116.1 22.3 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 TFIIA PF03153.13 KXS94700.1 - 0.21 11.5 18.1 0.24 11.4 18.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nucleo_P87 PF07267.11 KXS94700.1 - 0.32 9.8 9.4 0.36 9.6 9.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Epimerase PF01370.21 KXS94701.1 - 6.4e-10 38.9 0.1 7.3e-10 38.7 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXS94701.1 - 1e-07 31.2 0.0 1.2e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KXS94701.1 - 3.7e-05 23.3 0.2 5e-05 22.9 0.2 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KXS94701.1 - 0.0021 17.6 0.0 0.004 16.6 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 KXS94701.1 - 0.0029 16.8 0.0 0.0034 16.6 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 KXS94701.1 - 0.032 14.2 0.6 0.4 10.6 0.6 2.3 1 1 0 1 1 1 0 KR domain NAD_binding_4 PF07993.12 KXS94701.1 - 0.033 13.3 0.2 5.2 6.2 0.0 2.0 2 0 0 2 2 2 0 Male sterility protein NAD_binding_2 PF03446.15 KXS94701.1 - 0.097 12.8 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase MFS_1 PF07690.16 KXS94702.1 - 3.7e-30 105.1 32.8 3.7e-30 105.0 32.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily PTR2 PF00854.21 KXS94702.1 - 0.00011 21.2 3.5 0.00046 19.1 3.0 2.2 2 0 0 2 2 2 1 POT family Neurensin PF14927.6 KXS94702.1 - 2.3 7.9 12.5 2.7 7.7 0.5 4.0 4 1 1 5 5 5 0 Neurensin RICTOR_N PF14664.6 KXS94703.1 - 4e-122 407.8 2.0 2.5e-120 401.9 0.1 3.3 3 1 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 KXS94703.1 - 2.9e-39 133.0 0.1 1.5e-36 124.3 0.0 3.9 3 1 1 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 KXS94703.1 - 1.8e-38 131.2 0.1 1.2e-35 122.2 0.0 3.9 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 KXS94703.1 - 5.2e-29 100.3 0.4 9e-27 93.1 0.1 3.2 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 KXS94703.1 - 3.7e-13 49.4 11.2 1.2e-12 47.8 11.2 1.9 1 0 0 1 1 1 1 Hr1 repeat MgsA_C PF12002.8 KXS94704.1 - 9.4e-57 191.6 0.0 1.7e-56 190.7 0.0 1.4 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 KXS94704.1 - 3.4e-20 72.2 0.1 7.1e-20 71.1 0.1 1.5 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 KXS94704.1 - 1e-14 55.1 0.0 2.5e-14 53.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KXS94704.1 - 2.7e-10 40.2 0.0 5.8e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 KXS94704.1 - 1.7e-05 24.6 0.0 0.00046 19.9 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 KXS94704.1 - 8.8e-05 22.5 0.0 0.0039 17.2 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXS94704.1 - 8.9e-05 22.9 0.3 0.021 15.2 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain Mg_chelatase PF01078.21 KXS94704.1 - 0.0001 21.7 0.1 0.23 10.8 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KXS94704.1 - 0.00013 21.8 0.0 0.00041 20.2 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXS94704.1 - 0.00023 21.5 0.0 0.00057 20.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 KXS94704.1 - 0.002 18.3 0.0 0.0039 17.3 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_14 PF13173.6 KXS94704.1 - 0.0027 17.8 0.0 0.0052 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KXS94704.1 - 0.0036 17.5 0.2 0.0082 16.4 0.2 1.7 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 KXS94704.1 - 0.0038 16.5 0.0 0.0059 15.8 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_19 PF13245.6 KXS94704.1 - 0.011 16.0 0.6 0.052 13.9 0.5 1.8 1 1 1 2 2 2 0 AAA domain AAA_30 PF13604.6 KXS94704.1 - 0.013 15.2 0.2 0.035 13.8 0.2 1.7 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 KXS94704.1 - 0.014 14.5 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) SKI PF01202.22 KXS94704.1 - 0.023 14.8 0.0 0.039 14.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate kinase ResIII PF04851.15 KXS94704.1 - 0.031 14.3 0.3 1.2 9.1 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Zeta_toxin PF06414.12 KXS94704.1 - 0.044 13.1 0.0 0.092 12.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 KXS94704.1 - 0.056 14.0 0.1 0.29 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KXS94704.1 - 0.063 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KXS94704.1 - 0.069 13.2 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE zf-WRNIP1_ubi PF18279.1 KXS94704.1 - 0.083 13.6 0.1 0.24 12.1 0.1 1.9 1 0 0 1 1 1 0 Werner helicase-interacting protein 1 ubiquitin-binding domain AAA_17 PF13207.6 KXS94704.1 - 0.15 12.5 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KXS94704.1 - 0.17 12.1 0.0 0.47 10.6 0.0 1.7 2 0 0 2 2 1 0 AAA domain Retinal PF15449.6 KXS94704.1 - 5.7 4.6 10.6 8.3 4.0 10.6 1.1 1 0 0 1 1 1 0 Retinal protein Git3 PF11710.8 KXS94705.1 - 4.9e-17 62.4 13.9 1.6e-16 60.7 13.9 1.8 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 KXS94705.1 - 0.00029 20.8 0.2 0.00094 19.2 0.2 1.9 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term Dicty_CAR PF05462.11 KXS94705.1 - 0.0028 16.9 16.2 0.0043 16.2 16.2 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor DEAD PF00270.29 KXS94706.1 - 1.3e-46 158.6 0.0 4.6e-46 156.8 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXS94706.1 - 4.6e-29 101.0 0.1 2.6e-28 98.6 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXS94706.1 - 0.0016 18.5 0.0 0.0038 17.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3334 PF11813.8 KXS94706.1 - 0.13 11.9 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) APH PF01636.23 KXS94707.1 - 5.9e-05 23.1 1.4 0.00012 22.1 1.4 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family RhoGAP PF00620.27 KXS94708.1 - 1.5e-28 99.5 0.0 2.4e-28 98.9 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain KAR9 PF08580.10 KXS94710.1 - 2.3 6.6 16.0 3 6.3 16.0 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Fungal_trans_2 PF11951.8 KXS94711.1 - 0.013 14.3 0.2 0.023 13.5 0.2 1.4 1 1 0 1 1 1 0 Fungal specific transcription factor domain FKBP_C PF00254.28 KXS94712.1 - 7.2e-24 83.9 0.0 8.5e-24 83.7 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase AAA_3 PF07726.11 KXS94714.1 - 0.0031 17.4 0.0 0.0052 16.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Dsh_C PF12316.8 KXS94714.1 - 0.026 14.9 0.6 0.041 14.3 0.6 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal PHP PF02811.19 KXS94715.1 - 9.1e-15 55.3 0.7 1.9e-14 54.3 0.7 1.5 1 1 0 1 1 1 1 PHP domain Borrelia_lipo_1 PF05714.11 KXS94717.1 - 0.06 13.1 0.9 0.1 12.4 0.4 1.5 1 1 1 2 2 2 0 Borrelia burgdorferi virulent strain associated lipoprotein DED PF01335.21 KXS94717.1 - 0.13 12.6 0.6 30 5.0 0.0 2.9 2 1 0 3 3 3 0 Death effector domain Prenyltrans PF00432.21 KXS94718.1 - 2e-61 203.4 9.1 5.2e-14 51.7 0.0 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 KXS94718.1 - 5.9e-06 25.6 0.0 0.00018 20.7 0.0 2.1 1 1 1 2 2 2 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 KXS94718.1 - 0.003 16.7 0.0 11 5.0 0.0 4.2 1 1 4 5 5 5 2 Squalene-hopene cyclase N-terminal domain DUF3386 PF11866.8 KXS94719.1 - 0.013 15.0 0.2 0.023 14.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3386) zf-C2H2_2 PF12756.7 KXS94719.1 - 0.045 14.1 0.2 0.087 13.2 0.2 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) HGTP_anticodon PF03129.20 KXS94724.1 - 3.8e-18 65.4 0.0 3.8e-18 65.4 0.0 2.8 4 0 0 4 4 4 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KXS94724.1 - 4.7e-07 30.0 0.0 2.7e-06 27.5 0.0 2.2 3 0 0 3 3 3 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF4320 PF14208.6 KXS94724.1 - 0.25 11.4 0.8 3.4 7.8 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4320) IPP-2 PF04979.14 KXS94725.1 - 1.4e-20 74.4 15.1 1.4e-20 74.4 15.1 2.3 2 1 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) GYF PF02213.16 KXS94727.1 - 1.5e-10 40.6 1.6 3.3e-10 39.4 1.6 1.6 1 0 0 1 1 1 1 GYF domain R3H PF01424.22 KXS94728.1 - 2.1e-11 43.6 0.1 4.7e-11 42.5 0.1 1.6 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.22 KXS94728.1 - 2e-07 30.7 0.1 3.8e-07 29.8 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_M66 PF10462.9 KXS94728.1 - 0.03 13.3 0.2 0.1 11.5 0.1 1.9 2 0 0 2 2 2 0 Peptidase M66 RRM_2 PF04059.12 KXS94728.1 - 0.19 12.0 0.1 0.31 11.3 0.1 1.3 1 0 0 1 1 1 0 RNA recognition motif 2 Brix PF04427.18 KXS94729.1 - 1.4e-25 90.5 0.0 2.1e-25 90.0 0.0 1.3 1 0 0 1 1 1 1 Brix domain BUD22 PF09073.10 KXS94729.1 - 0.46 9.8 18.3 0.66 9.3 18.3 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 KXS94729.1 - 0.63 8.2 21.4 0.82 7.8 21.4 1.1 1 0 0 1 1 1 0 Nop14-like family Gram_pos_anchor PF00746.21 KXS94731.1 - 0.0036 17.2 1.5 0.007 16.3 1.5 1.5 1 0 0 1 1 1 1 LPXTG cell wall anchor motif PepSY_TM PF03929.16 KXS94731.1 - 0.0038 16.9 1.0 0.0049 16.6 0.1 1.5 1 1 1 2 2 2 1 PepSY-associated TM region EphA2_TM PF14575.6 KXS94731.1 - 0.025 15.5 0.0 0.04 14.8 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MtrF PF09472.10 KXS94731.1 - 0.92 8.9 3.0 1.5 8.3 3.0 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) FAD_binding_4 PF01565.23 KXS94732.1 - 4.2e-20 71.9 1.4 8.3e-20 70.9 1.4 1.5 1 0 0 1 1 1 1 FAD binding domain Cupin_2 PF07883.11 KXS94732.1 - 9.6e-09 34.8 0.1 0.00024 20.8 0.0 2.5 2 0 0 2 2 2 2 Cupin domain BBE PF08031.12 KXS94732.1 - 1.3e-05 25.2 0.0 2.7e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like AraC_binding PF02311.19 KXS94732.1 - 6.9e-05 22.8 0.6 0.12 12.3 0.1 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_6 PF12852.7 KXS94732.1 - 0.00051 19.8 0.2 0.31 10.8 0.0 2.6 1 1 0 2 2 2 2 Cupin Cupin_3 PF05899.12 KXS94732.1 - 0.006 16.2 0.0 0.27 11.0 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF861) Blt1_C PF17183.4 KXS94732.1 - 0.064 12.9 2.4 1.8 8.3 0.1 3.1 3 0 0 3 3 3 0 Get5 carboxyl domain Rft-1 PF04506.13 KXS94733.1 - 1.2e-147 492.8 9.1 1.4e-147 492.6 9.1 1.0 1 0 0 1 1 1 1 Rft protein FUSC PF04632.12 KXS94734.1 - 0.02 13.5 0.2 0.029 12.9 0.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family SKG6 PF08693.10 KXS94734.1 - 0.053 12.9 0.0 0.087 12.2 0.0 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EphA2_TM PF14575.6 KXS94734.1 - 0.11 13.4 0.0 0.26 12.2 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain adh_short_C2 PF13561.6 KXS94735.1 - 4e-57 193.5 0.3 4.6e-57 193.3 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS94735.1 - 6.7e-38 130.1 0.3 8.1e-38 129.8 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS94735.1 - 3.3e-13 49.9 0.3 5.1e-13 49.3 0.3 1.2 1 0 0 1 1 1 1 KR domain Glyco_hydro_1 PF00232.18 KXS94735.1 - 0.05 12.0 0.0 0.064 11.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 S4 PF01479.25 KXS94735.1 - 0.087 12.6 0.1 0.26 11.0 0.0 1.9 2 0 0 2 2 2 0 S4 domain WD40 PF00400.32 KXS94737.1 - 1.7e-15 57.1 14.9 0.005 17.6 0.0 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS94737.1 - 0.0021 18.3 0.1 5.4 7.4 0.0 3.6 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain GMC_oxred_N PF00732.19 KXS94738.1 - 6.3e-08 32.3 0.0 8.2e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase AIM24 PF01987.17 KXS94739.1 - 4e-52 177.0 0.1 4.7e-52 176.7 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Pkinase PF00069.25 KXS94740.1 - 7.1e-26 91.1 0.0 3e-25 89.1 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS94740.1 - 1.6e-16 60.4 0.0 2.4e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXS94740.1 - 0.002 17.0 0.0 0.0027 16.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXS94740.1 - 0.0034 17.3 1.7 1.8 8.4 0.1 2.3 1 1 0 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KXS94740.1 - 0.15 11.3 0.0 1.9 7.8 0.0 2.3 1 1 0 1 1 1 0 Kinase-like fn3 PF00041.21 KXS94741.1 - 0.00035 20.9 0.0 0.0009 19.5 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III domain CDT1_C PF16679.5 KXS94742.1 - 6.5e-23 81.0 3.3 1.2e-22 80.2 0.9 2.7 2 0 0 2 2 2 1 DNA replication factor Cdt1 C-terminal domain MFS_1 PF07690.16 KXS94744.1 - 2.3e-23 82.7 27.6 2.3e-23 82.7 27.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXS94744.1 - 1.9e-06 26.6 1.8 3.3e-06 25.8 1.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) BT1 PF03092.16 KXS94744.1 - 0.0036 15.6 1.3 0.0091 14.3 1.3 1.6 1 0 0 1 1 1 1 BT1 family DUF4191 PF13829.6 KXS94744.1 - 0.47 9.8 8.8 3.1 7.1 0.3 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) 4HFCP_synth PF04476.13 KXS94745.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 4-HFC-P synthase Aldedh PF00171.22 KXS94746.1 - 9.3e-141 469.5 0.0 1.1e-140 469.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3813 PF12758.7 KXS94746.1 - 0.15 12.4 0.1 0.37 11.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3813) GST_C_2 PF13410.6 KXS94749.1 - 0.023 14.7 0.0 0.074 13.1 0.0 1.9 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain HTH_38 PF13936.6 KXS94750.1 - 4.4e-12 45.5 3.1 0.072 12.9 0.1 6.8 7 0 0 7 7 7 3 Helix-turn-helix domain HTH_23 PF13384.6 KXS94750.1 - 1.2e-10 40.9 0.1 0.00067 19.4 0.0 5.2 5 0 0 5 5 5 2 Homeodomain-like domain HTH_29 PF13551.6 KXS94750.1 - 1.8e-09 37.5 1.0 1.4e-05 25.0 0.0 4.5 5 1 1 6 6 5 2 Winged helix-turn helix HTH_Tnp_1 PF01527.20 KXS94750.1 - 2.7e-08 34.0 4.7 0.096 13.0 0.0 5.6 6 1 1 7 7 7 2 Transposase HTH_28 PF13518.6 KXS94750.1 - 5.5e-08 32.8 1.2 0.016 15.3 0.0 4.4 6 0 0 6 6 4 2 Helix-turn-helix domain GerE PF00196.19 KXS94750.1 - 1.5e-07 30.9 0.1 0.6 9.7 0.0 4.8 5 1 1 6 6 6 2 Bacterial regulatory proteins, luxR family HTH_7 PF02796.15 KXS94750.1 - 6.1e-06 26.2 2.0 5.1 7.3 0.2 5.3 6 0 0 6 6 6 2 Helix-turn-helix domain of resolvase Sigma70_r4_2 PF08281.12 KXS94750.1 - 1.8e-05 24.3 0.2 2.2 8.0 0.0 4.9 5 0 0 5 5 5 1 Sigma-70, region 4 HTH_32 PF13565.6 KXS94750.1 - 6.4e-05 23.5 12.8 2.1 9.0 0.1 5.2 3 3 3 6 6 6 3 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 KXS94750.1 - 0.00021 20.6 1.5 0.98 8.9 0.1 4.7 5 0 0 5 5 5 1 Helix-turn-helix domain of transposase family ISL3 Myb_DNA-binding PF00249.31 KXS94750.1 - 0.00054 20.1 0.1 0.018 15.2 0.0 3.3 4 0 0 4 4 3 1 Myb-like DNA-binding domain HTH_24 PF13412.6 KXS94750.1 - 0.0042 16.6 0.0 2.5 7.7 0.0 3.4 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding MerR PF00376.23 KXS94750.1 - 0.056 13.2 2.5 10 6.0 0.0 3.8 4 0 0 4 4 4 0 MerR family regulatory protein Sigma70_r4 PF04545.16 KXS94750.1 - 0.077 12.5 0.4 14 5.2 0.0 3.5 4 0 0 4 4 4 0 Sigma-70, region 4 DUF2774 PF11242.8 KXS94750.1 - 0.12 12.5 0.0 9 6.6 0.0 2.8 2 1 1 3 3 2 0 Protein of unknown function (DUF2774) MerR_1 PF13411.6 KXS94750.1 - 0.14 12.3 0.5 75 3.5 0.0 3.7 3 1 0 3 3 3 0 MerR HTH family regulatory protein HTH_Tnp_Tc3_1 PF11427.8 KXS94750.1 - 0.15 11.9 0.2 4.8 7.1 0.0 3.1 4 0 0 4 4 3 0 Tc3 transposase DUF2285 PF10074.9 KXS94750.1 - 0.29 11.8 4.0 0.4 11.3 1.2 2.6 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2285) GcrA PF07750.11 KXS94750.1 - 2 8.8 5.4 6.5 7.1 0.0 3.5 4 1 1 5 5 5 0 GcrA cell cycle regulator CWC25 PF12542.8 KXS94752.1 - 0.13 13.1 5.9 3 8.8 6.0 2.6 1 1 0 1 1 1 0 Pre-mRNA splicing factor DivIC PF04977.15 KXS94753.1 - 0.21 11.4 16.9 0.24 11.2 0.1 3.8 2 2 1 3 3 3 0 Septum formation initiator bZIP_1 PF00170.21 KXS94753.1 - 1.2 9.3 19.2 0.59 10.3 0.1 3.7 4 0 0 4 4 4 0 bZIP transcription factor MT PF12777.7 KXS94753.1 - 2.7 6.9 8.7 0.94 8.4 2.9 2.2 1 1 1 2 2 2 0 Microtubule-binding stalk of dynein motor FAP PF07174.11 KXS94753.1 - 3.6 7.0 9.0 5.4 6.4 9.0 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) HALZ PF02183.18 KXS94753.1 - 7.1 6.9 15.2 5.5 7.3 0.5 3.3 3 0 0 3 3 3 0 Homeobox associated leucine zipper DLH PF01738.18 KXS94755.1 - 1.9e-16 60.3 0.0 2.1e-08 34.0 0.0 2.5 2 1 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 KXS94755.1 - 0.0011 18.9 0.0 0.0026 17.7 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold PP2C PF00481.21 KXS94756.1 - 8.1e-38 130.5 0.0 9.8e-32 110.6 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 KXS94756.1 - 0.0015 18.2 0.0 0.0055 16.4 0.0 1.9 2 1 0 2 2 2 1 Protein phosphatase 2C adh_short_C2 PF13561.6 KXS94759.1 - 4.1e-55 186.9 0.4 5.2e-55 186.5 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS94759.1 - 6.4e-42 143.2 0.2 8.5e-42 142.8 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_25 PF13649.6 KXS94759.1 - 0.002 18.8 0.0 0.0042 17.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain KR PF08659.10 KXS94759.1 - 0.024 14.5 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 KR domain DUF1772 PF08592.11 KXS94763.1 - 7e-06 26.4 1.4 1.2e-05 25.6 1.4 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) Arm PF00514.23 KXS94764.1 - 7e-74 241.9 31.0 9.9e-13 47.6 0.1 11.4 11 1 1 12 12 12 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KXS94764.1 - 8.2e-20 71.0 5.4 0.00021 21.6 0.1 6.8 4 1 1 6 6 6 5 HEAT repeats HEAT PF02985.22 KXS94764.1 - 4.4e-15 54.5 13.0 0.27 11.6 0.0 9.1 10 0 0 10 10 8 4 HEAT repeat HEAT_EZ PF13513.6 KXS94764.1 - 1.2e-14 54.4 15.8 0.0022 18.4 0.1 7.9 6 1 3 9 9 7 5 HEAT-like repeat Arm_2 PF04826.13 KXS94764.1 - 1.4e-11 44.3 3.2 1.3e-06 28.1 1.3 2.9 1 1 0 2 2 2 2 Armadillo-like KAP PF05804.12 KXS94764.1 - 1.8e-10 39.6 0.2 5.9e-10 38.0 0.1 1.7 2 0 0 2 2 2 1 Kinesin-associated protein (KAP) Adaptin_N PF01602.20 KXS94764.1 - 6.9e-10 38.1 4.3 1.1e-05 24.2 0.4 2.7 1 1 1 2 2 2 2 Adaptin N terminal region V-ATPase_H_N PF03224.14 KXS94764.1 - 1.9e-07 30.7 0.7 0.001 18.4 0.8 3.6 2 1 1 3 3 3 2 V-ATPase subunit H Cnd1 PF12717.7 KXS94764.1 - 1.2e-05 25.5 5.8 0.0091 16.1 0.3 5.0 3 2 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_C PF11698.8 KXS94764.1 - 0.00012 22.1 2.1 1.4 9.0 0.1 5.1 3 1 3 6 6 6 2 V-ATPase subunit H DUF3361 PF11841.8 KXS94764.1 - 0.00021 21.3 5.5 2.6 7.9 0.2 4.1 1 1 1 3 3 3 2 Domain of unknown function (DUF3361) SUFU PF05076.13 KXS94764.1 - 0.0011 19.0 0.0 0.0042 17.1 0.0 1.8 2 0 0 2 2 2 1 Suppressor of fused protein (SUFU) FeoB_Cyto PF17910.1 KXS94764.1 - 0.018 15.6 0.0 0.05 14.1 0.0 1.7 1 0 0 1 1 1 0 FeoB cytosolic helical domain HEAT_PBS PF03130.16 KXS94764.1 - 0.02 15.5 4.1 99 4.1 0.0 6.4 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat Atx10homo_assoc PF09759.9 KXS94764.1 - 0.062 13.3 6.2 3.4 7.8 0.1 4.8 2 1 3 6 6 6 0 Spinocerebellar ataxia type 10 protein domain Vac14_Fab1_bd PF12755.7 KXS94764.1 - 0.077 13.6 0.0 2.1 9.0 0.0 3.2 2 1 2 4 4 4 0 Vacuolar 14 Fab1-binding region Exonuc_VII_S PF02609.16 KXS94764.1 - 0.37 10.9 1.9 1.8 8.7 0.3 2.6 2 0 0 2 2 2 0 Exonuclease VII small subunit RasGEF_N_2 PF14663.6 KXS94764.1 - 2.9 8.3 4.5 65 4.0 0.2 3.8 2 1 1 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain SAM_1 PF00536.30 KXS94766.1 - 0.15 12.6 0.1 11 6.6 0.0 2.4 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) DUF1907 PF08925.11 KXS94767.1 - 2.4e-115 384.9 0.0 2.7e-115 384.7 0.0 1.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1907) Fasciclin PF02469.22 KXS94768.1 - 6.6e-52 175.1 1.7 3.5e-29 101.6 0.2 2.2 2 0 0 2 2 2 2 Fasciclin domain GST_N_3 PF13417.6 KXS94769.1 - 3e-08 34.0 0.0 6.1e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXS94769.1 - 3e-08 33.8 0.0 6e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXS94769.1 - 4e-08 33.4 0.0 8.3e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXS94769.1 - 1.2e-05 25.4 0.0 2.7e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KXS94769.1 - 0.001 19.4 0.0 0.0016 18.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXS94769.1 - 0.0033 17.4 0.0 0.0064 16.5 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 KXS94769.1 - 0.05 13.8 0.0 0.7 10.2 0.0 2.2 2 0 0 2 2 2 0 Glutaredoxin Cnn_1N PF07989.11 KXS94770.1 - 0.0065 16.6 10.3 0.02 15.1 3.1 2.4 2 0 0 2 2 2 2 Centrosomin N-terminal motif 1 FUSC PF04632.12 KXS94770.1 - 0.4 9.1 4.9 0.48 8.9 4.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1664 PF07889.12 KXS94770.1 - 0.67 10.0 4.1 0.98 9.5 3.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) bZIP_1 PF00170.21 KXS94770.1 - 0.85 9.8 8.4 0.82 9.8 1.4 2.4 1 1 1 2 2 2 0 bZIP transcription factor ZapB PF06005.12 KXS94770.1 - 1.4 9.5 13.7 0.46 11.0 10.3 1.9 1 1 1 2 2 2 0 Cell division protein ZapB YabA PF06156.13 KXS94770.1 - 10 6.9 13.1 13 6.5 5.5 2.6 1 1 2 3 3 3 0 Initiation control protein YabA Pkinase_Tyr PF07714.17 KXS94771.1 - 4.7e-20 72.0 0.0 7.6e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXS94771.1 - 3.6e-17 62.6 0.0 5.5e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KXS94771.1 - 0.19 11.0 0.0 0.31 10.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pterin_4a PF01329.19 KXS94774.1 - 0.018 15.2 0.1 0.018 15.2 0.1 1.5 2 0 0 2 2 2 0 Pterin 4 alpha carbinolamine dehydratase TPR_12 PF13424.6 KXS94775.1 - 0.00017 21.8 0.1 0.0012 19.1 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 KXS94775.1 - 0.0017 18.2 0.0 0.0088 15.9 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat Chromo PF00385.24 KXS94788.1 - 0.0012 18.7 0.4 0.02 14.8 0.1 2.3 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain SNAD4 PF18750.1 KXS94788.1 - 0.075 13.2 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 MFS_1 PF07690.16 KXS94790.1 - 2.8e-24 85.7 19.5 3.4e-24 85.4 19.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily GMC_oxred_N PF00732.19 KXS94791.1 - 1.7e-54 185.3 0.0 2.3e-54 184.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXS94791.1 - 1.1e-38 132.9 0.0 1.8e-38 132.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KXS94791.1 - 1.2e-05 24.6 0.0 0.12 11.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KXS94791.1 - 1.3e-05 25.3 0.0 5.1e-05 23.4 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KXS94791.1 - 1.8e-05 24.0 0.0 2.6e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KXS94791.1 - 0.00016 21.4 0.0 0.0048 16.5 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXS94791.1 - 0.0012 18.2 0.0 0.0056 16.0 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXS94791.1 - 0.0053 17.3 0.2 0.43 11.2 0.0 2.9 4 0 0 4 4 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXS94791.1 - 0.014 14.8 0.0 0.64 9.3 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KXS94791.1 - 0.016 14.1 0.0 0.022 13.6 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase Thi4 PF01946.17 KXS94791.1 - 0.027 13.7 0.0 0.11 11.7 0.0 2.0 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 KXS94791.1 - 0.059 12.1 0.0 0.18 10.5 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein Fungal_trans PF04082.18 KXS94792.1 - 9.4e-33 113.4 0.0 1.3e-32 112.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain CstA_5TM PF13722.6 KXS94792.1 - 0.061 13.7 0.0 0.66 10.4 0.0 2.3 2 0 0 2 2 2 0 5TM C-terminal transporter carbon starvation CstA Aldedh PF00171.22 KXS94793.1 - 9.4e-153 509.0 0.0 1.1e-152 508.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family NCD1 PF04904.13 KXS94793.1 - 0.096 12.7 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 NAB conserved region 1 (NCD1) DHDPS PF00701.22 KXS94794.1 - 9.1e-35 119.8 0.0 1.1e-34 119.5 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family MFS_1 PF07690.16 KXS94795.1 - 6.5e-36 124.0 33.1 6.5e-36 124.0 33.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Consortin_C PF15281.6 KXS94795.1 - 0.13 12.2 0.4 18 5.4 0.0 2.6 3 0 0 3 3 3 0 Consortin C-terminus OATP PF03137.20 KXS94795.1 - 2.6 6.2 16.1 0.024 13.0 3.0 2.9 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DNMT1-RFD PF12047.8 KXS94796.1 - 0.023 14.7 0.0 0.058 13.4 0.0 1.6 1 0 0 1 1 1 0 Cytosine specific DNA methyltransferase replication foci domain GrpB PF04229.14 KXS94797.1 - 2.2e-52 177.5 0.1 2.6e-52 177.3 0.1 1.1 1 0 0 1 1 1 1 GrpB protein PX PF00787.24 KXS94798.1 - 1.4e-16 60.4 0.0 3.6e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 KXS94798.1 - 1.7e-07 31.0 12.1 0.00088 18.9 2.8 2.2 2 0 0 2 2 2 2 Vps5 C terminal like Cas_Csy4 PF09618.10 KXS94798.1 - 0.16 12.1 1.2 1.7 8.8 1.0 2.3 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csy4) Peptidase_C10 PF01640.17 KXS94798.1 - 0.17 12.1 0.1 0.32 11.3 0.1 1.4 1 0 0 1 1 1 0 Peptidase C10 family DHHC PF01529.20 KXS94799.1 - 6.5e-38 129.9 5.8 6.5e-38 129.9 5.8 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase FtsX PF02687.21 KXS94799.1 - 0.084 13.3 1.3 0.11 13.0 0.0 1.8 2 0 0 2 2 2 0 FtsX-like permease family Spt4 PF06093.13 KXS94799.1 - 0.31 11.2 3.8 0.65 10.1 3.8 1.5 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger Yip1 PF04893.17 KXS94799.1 - 2.2 8.0 13.6 0.14 11.9 4.1 2.2 2 0 0 2 2 2 0 Yip1 domain OGFr_N PF04664.13 KXS94801.1 - 7.2e-18 64.9 0.0 1e-17 64.4 0.0 1.2 1 0 0 1 1 1 1 Opioid growth factor receptor (OGFr) conserved region TruB_N PF01509.18 KXS94802.1 - 5.9e-43 146.8 0.0 1.7e-42 145.3 0.0 1.7 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KXS94802.1 - 2.5e-08 33.9 0.0 6.9e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain Spo0M PF07070.11 KXS94802.1 - 0.013 15.1 0.1 0.022 14.3 0.1 1.3 1 0 0 1 1 1 0 SpoOM protein Apidaecin PF00807.17 KXS94803.1 - 0.033 14.3 10.1 4.8 7.4 0.4 3.8 3 0 0 3 3 3 0 Apidaecin Cauli_DNA-bind PF03310.13 KXS94803.1 - 0.08 13.0 0.3 4 7.5 0.0 2.6 1 1 1 2 2 2 0 Caulimovirus DNA-binding protein HSBP1 PF06825.12 KXS94804.1 - 4.3e-18 64.9 0.2 6.4e-18 64.4 0.2 1.3 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Matrilin_ccoil PF10393.9 KXS94804.1 - 9.8e-05 22.1 0.2 0.00035 20.4 0.2 1.8 1 1 0 1 1 1 1 Trimeric coiled-coil oligomerisation domain of matrilin Baculo_PEP_C PF04513.12 KXS94804.1 - 0.026 14.6 1.9 0.04 14.0 1.9 1.3 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlxA PF14282.6 KXS94804.1 - 0.05 13.6 2.3 0.74 9.8 0.4 2.1 1 1 1 2 2 2 0 FlxA-like protein ABC_tran_CTD PF16326.5 KXS94804.1 - 0.053 13.8 0.2 0.13 12.5 0.1 1.7 1 1 0 1 1 1 0 ABC transporter C-terminal domain NPV_P10 PF05531.12 KXS94804.1 - 0.06 13.8 0.9 0.091 13.2 0.2 1.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein CLASP_N PF12348.8 KXS94805.1 - 0.0016 18.1 0.0 0.065 12.8 0.0 2.4 2 0 0 2 2 2 1 CLASP N terminal Fez1 PF06818.15 KXS94805.1 - 0.012 16.1 0.9 0.012 16.1 0.9 2.0 2 0 0 2 2 2 0 Fez1 Golgin_A5 PF09787.9 KXS94805.1 - 0.11 12.0 7.5 0.21 11.0 7.5 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 bZIP_2 PF07716.15 KXS94805.1 - 0.38 10.9 8.0 0.16 12.1 0.3 3.3 2 1 1 3 3 3 0 Basic region leucine zipper HEAT PF02985.22 KXS94805.1 - 0.46 10.9 5.6 11 6.6 0.0 4.5 5 0 0 5 5 5 0 HEAT repeat Tup_N PF08581.10 KXS94805.1 - 0.51 10.7 4.5 6.3 7.2 4.3 2.5 1 1 0 1 1 1 0 Tup N-terminal DUF4763 PF15960.5 KXS94805.1 - 0.69 9.2 6.5 1.6 8.0 6.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Atg14 PF10186.9 KXS94805.1 - 0.91 8.6 7.9 2.2 7.3 7.9 1.6 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Syntaxin PF00804.25 KXS94805.1 - 2.1 8.0 10.6 0.31 10.7 5.1 2.4 3 0 0 3 3 3 0 Syntaxin FUSC PF04632.12 KXS94805.1 - 3.7 6.0 6.3 9.5 4.6 0.0 2.4 2 0 0 2 2 2 0 Fusaric acid resistance protein family CLASP_N PF12348.8 KXS94806.1 - 0.0016 18.1 0.0 0.065 12.8 0.0 2.4 2 0 0 2 2 2 1 CLASP N terminal Fez1 PF06818.15 KXS94806.1 - 0.012 16.1 0.9 0.012 16.1 0.9 2.0 2 0 0 2 2 2 0 Fez1 Golgin_A5 PF09787.9 KXS94806.1 - 0.11 12.0 7.5 0.21 11.0 7.5 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 bZIP_2 PF07716.15 KXS94806.1 - 0.38 10.9 8.0 0.16 12.1 0.3 3.3 2 1 1 3 3 3 0 Basic region leucine zipper HEAT PF02985.22 KXS94806.1 - 0.46 10.9 5.6 11 6.6 0.0 4.5 5 0 0 5 5 5 0 HEAT repeat Tup_N PF08581.10 KXS94806.1 - 0.51 10.7 4.5 6.3 7.2 4.3 2.5 1 1 0 1 1 1 0 Tup N-terminal DUF4763 PF15960.5 KXS94806.1 - 0.69 9.2 6.5 1.6 8.0 6.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Atg14 PF10186.9 KXS94806.1 - 0.91 8.6 7.9 2.2 7.3 7.9 1.6 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Syntaxin PF00804.25 KXS94806.1 - 2.1 8.0 10.6 0.31 10.7 5.1 2.4 3 0 0 3 3 3 0 Syntaxin FUSC PF04632.12 KXS94806.1 - 3.7 6.0 6.3 9.5 4.6 0.0 2.4 2 0 0 2 2 2 0 Fusaric acid resistance protein family Lipase_GDSL_2 PF13472.6 KXS94808.1 - 2.3e-11 44.4 0.3 3.3e-11 43.9 0.3 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXS94808.1 - 4.4e-07 30.1 0.0 5.1e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase SLAC1 PF03595.17 KXS94809.1 - 6.2e-83 278.7 46.4 7.3e-83 278.5 46.4 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel BPA_C PF18040.1 KXS94809.1 - 0.029 14.3 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 beta porphyranase A C-terminal RseC_MucC PF04246.12 KXS94809.1 - 3.4 7.6 9.1 0.11 12.5 0.5 2.5 2 1 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC UPF0016 PF01169.19 KXS94810.1 - 8.1e-42 141.4 26.5 8.5e-21 74.1 12.1 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 DUF2070 PF09843.9 KXS94810.1 - 0.058 11.7 0.9 0.091 11.0 0.9 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) G3P_acyltransf PF02660.15 KXS94810.1 - 6.5 6.8 14.7 3.2 7.8 2.1 2.3 2 0 0 2 2 2 0 Glycerol-3-phosphate acyltransferase U3_snoRNA_assoc PF08297.11 KXS94811.1 - 0.079 13.7 8.0 1.8 9.3 2.7 3.0 2 0 0 2 2 2 0 U3 snoRNA associated SIMPL PF04402.14 KXS94811.1 - 4.9 7.6 9.6 23 5.4 9.6 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF541) AAA_11 PF13086.6 KXS94811.1 - 5.6 6.7 7.1 4.8 6.9 1.0 2.2 2 0 0 2 2 2 0 AAA domain AAR2 PF05282.11 KXS94812.1 - 6.2e-95 318.6 0.0 9.7e-95 317.9 0.0 1.3 1 0 0 1 1 1 1 AAR2 protein MOSC_N PF03476.16 KXS94812.1 - 0.23 11.3 1.4 2.5 8.0 0.1 2.9 3 0 0 3 3 3 0 MOSC N-terminal beta barrel domain Cwf_Cwc_15 PF04889.12 KXS94813.1 - 0.0057 16.4 16.2 0.0057 16.4 16.2 2.3 2 1 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein Dicty_REP PF05086.12 KXS94813.1 - 0.099 10.6 3.4 0.15 10.0 3.4 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein NOA36 PF06524.12 KXS94813.1 - 0.18 11.1 16.5 0.39 10.0 16.5 1.5 1 0 0 1 1 1 0 NOA36 protein RRN3 PF05327.11 KXS94813.1 - 1.1 7.7 6.9 2.4 6.6 6.9 1.5 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 GCIP PF13324.6 KXS94813.1 - 7.8 6.0 9.4 16 5.0 9.4 1.5 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting His_Phos_2 PF00328.22 KXS94815.1 - 3.1e-108 362.5 0.1 4.8e-108 361.9 0.1 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 KXS94815.1 - 6.9e-37 125.5 0.0 1.5e-36 124.4 0.0 1.6 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 KXS94815.1 - 1.7e-06 27.7 0.2 4.4e-06 26.4 0.0 1.7 2 0 0 2 2 2 1 RimK-like ATP-grasp domain Utp21 PF04192.12 KXS94816.1 - 4.3e-71 239.1 0.1 5.8e-71 238.7 0.1 1.1 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 KXS94816.1 - 5e-12 46.0 0.0 0.8 10.1 0.0 6.4 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXS94816.1 - 6.6e-11 42.6 20.1 0.088 13.7 0.0 8.7 9 0 0 9 9 9 4 WD domain, G-beta repeat Sulfotransfer_4 PF17784.1 KXS94820.1 - 8.5e-53 179.4 0.0 1e-52 179.1 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KXS94820.1 - 0.00047 20.6 0.1 0.0012 19.3 0.1 1.9 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_4 PF17784.1 KXS94821.1 - 8.5e-53 179.4 0.0 1e-52 179.1 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KXS94821.1 - 0.00047 20.6 0.1 0.0012 19.3 0.1 1.9 1 1 0 1 1 1 1 Sulfotransferase family Aldo_ket_red PF00248.21 KXS94822.1 - 1.1e-61 208.6 0.0 1.5e-61 208.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family TauD PF02668.16 KXS94823.1 - 6.3e-36 124.5 0.4 1.2e-35 123.7 0.4 1.4 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family XkdW PF09636.10 KXS94824.1 - 8.8 6.5 33.5 4.1 7.5 2.3 5.4 1 1 4 5 5 5 0 XkdW protein CorA PF01544.18 KXS94826.1 - 9.6e-10 38.2 0.1 1.8e-09 37.3 0.1 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2207 PF09972.9 KXS94827.1 - 0.0036 16.1 1.2 3.3 6.4 1.7 2.6 2 1 0 2 2 2 2 Predicted membrane protein (DUF2207) DUF2070 PF09843.9 KXS94827.1 - 0.0049 15.2 1.7 0.0071 14.7 1.7 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) TrbC PF04956.13 KXS94827.1 - 0.024 14.9 0.0 0.024 14.9 0.0 2.3 2 1 0 2 2 2 0 TrbC/VIRB2 family MLANA PF14991.6 KXS94827.1 - 0.025 14.8 0.1 0.071 13.4 0.0 1.9 2 0 0 2 2 1 0 Protein melan-A Form_Nir_trans PF01226.17 KXS94827.1 - 0.091 12.1 7.6 0.61 9.4 4.7 2.1 2 0 0 2 2 2 0 Formate/nitrite transporter DUF4448 PF14610.6 KXS94827.1 - 0.12 12.2 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Herpes_TAF50 PF03326.13 KXS94827.1 - 0.15 10.7 7.1 0.21 10.2 7.1 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) DUF4381 PF14316.6 KXS94827.1 - 0.18 12.0 1.9 0.35 11.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Keratin_assoc PF09775.9 KXS94827.1 - 0.25 11.0 2.2 4.8 6.9 2.1 2.2 2 0 0 2 2 2 0 Keratinocyte-associated protein 2 MHYT PF03707.16 KXS94827.1 - 0.27 11.4 2.4 0.66 10.2 0.1 2.5 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat Phage_holin_2_4 PF16082.5 KXS94827.1 - 0.32 10.8 1.1 0.7 9.7 0.0 2.1 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like SKG6 PF08693.10 KXS94827.1 - 2.1 7.8 5.3 5 6.6 5.3 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF2207 PF09972.9 KXS94828.1 - 0.0048 15.7 1.5 3.3 6.4 0.0 2.6 2 1 0 2 2 2 2 Predicted membrane protein (DUF2207) DUF2070 PF09843.9 KXS94828.1 - 0.0051 15.2 1.7 0.0073 14.7 1.7 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) TrbC PF04956.13 KXS94828.1 - 0.024 14.8 0.0 0.024 14.8 0.0 2.3 2 1 0 2 2 2 0 TrbC/VIRB2 family MLANA PF14991.6 KXS94828.1 - 0.025 14.9 0.1 0.072 13.4 0.0 1.9 2 0 0 2 2 1 0 Protein melan-A Form_Nir_trans PF01226.17 KXS94828.1 - 0.094 12.0 7.6 0.62 9.4 4.7 2.1 2 0 0 2 2 2 0 Formate/nitrite transporter DUF4448 PF14610.6 KXS94828.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Herpes_TAF50 PF03326.13 KXS94828.1 - 0.15 10.7 7.1 0.22 10.2 7.1 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) DUF4381 PF14316.6 KXS94828.1 - 0.19 11.9 1.9 0.36 11.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Keratin_assoc PF09775.9 KXS94828.1 - 0.26 11.0 2.2 4.8 6.8 2.1 2.2 2 0 0 2 2 2 0 Keratinocyte-associated protein 2 MHYT PF03707.16 KXS94828.1 - 0.28 11.4 2.4 0.67 10.2 0.1 2.5 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat Phage_holin_2_4 PF16082.5 KXS94828.1 - 0.33 10.7 1.1 0.71 9.7 0.0 2.1 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like SKG6 PF08693.10 KXS94828.1 - 2.1 7.8 5.3 5 6.6 5.3 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain zf-C2H2 PF00096.26 KXS94829.1 - 9.5e-05 22.7 14.2 0.01 16.3 1.8 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXS94829.1 - 0.00029 21.1 3.8 0.00029 21.1 3.8 2.2 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXS94829.1 - 0.002 18.8 11.5 0.079 13.8 2.9 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger PBP1_TM PF14812.6 KXS94829.1 - 3.7 8.0 7.3 11 6.5 7.3 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-C2H2 PF00096.26 KXS94830.1 - 9.5e-05 22.7 14.2 0.01 16.3 1.8 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXS94830.1 - 0.00029 21.1 3.8 0.00029 21.1 3.8 2.2 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXS94830.1 - 0.002 18.8 11.5 0.079 13.8 2.9 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger PBP1_TM PF14812.6 KXS94830.1 - 3.7 8.0 7.3 11 6.5 7.3 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Kinase-like PF14531.6 KXS94831.1 - 0.005 16.2 0.0 0.0094 15.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like SesA PF17107.5 KXS94831.1 - 0.011 16.0 0.1 0.011 16.0 0.1 2.7 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Helo_like_N PF17111.5 KXS94831.1 - 0.04 13.3 2.6 0.066 12.6 0.1 2.5 2 1 1 3 3 3 0 Fungal N-terminal domain of STAND proteins Baculo_PEP_C PF04513.12 KXS94831.1 - 0.68 10.0 3.2 1.5 8.9 1.5 2.3 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2730 PF10805.8 KXS94831.1 - 0.8 9.8 2.5 24 5.1 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) Plasmid_RAQPRD PF09686.10 KXS94831.1 - 1 9.6 5.8 8.3 6.7 0.0 4.1 2 1 1 4 4 4 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Sof1 PF04158.14 KXS94834.1 - 3.1e-33 113.9 17.2 4.9e-33 113.3 17.2 1.3 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 KXS94834.1 - 3.2e-30 103.7 11.5 1.5e-07 32.0 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS94834.1 - 2.5e-07 30.9 1.4 0.013 15.8 0.1 4.3 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXS94834.1 - 0.00013 22.0 0.1 0.00037 20.4 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A BBS2_Mid PF14783.6 KXS94834.1 - 0.0023 17.9 0.4 6.7 6.8 0.1 4.4 3 2 2 5 5 5 1 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 KXS94834.1 - 0.018 13.7 8.7 0.022 13.4 0.2 3.2 2 1 1 4 4 4 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KXS94834.1 - 0.043 12.8 0.0 1.6 7.6 0.0 2.9 1 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF885 PF05960.11 KXS94835.1 - 9.8e-42 144.3 3.0 9.8e-42 144.3 3.0 1.5 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF885) DUF3328 PF11807.8 KXS94836.1 - 1.9e-05 24.5 0.0 2.3e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 KXS94837.1 - 1.9e-05 24.5 0.0 2.3e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 KXS94838.1 - 1.9e-05 24.5 0.0 2.3e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) E1_DerP2_DerF2 PF02221.15 KXS94839.1 - 0.06 13.8 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 ML domain TFIIIC_sub6 PF10419.9 KXS94842.1 - 3.2e-15 55.8 0.0 7.5e-15 54.6 0.0 1.6 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain GDP_Man_Dehyd PF16363.5 KXS94843.1 - 3.3e-103 345.6 0.0 3.7e-103 345.4 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KXS94843.1 - 3.7e-51 173.9 0.0 5.1e-51 173.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KXS94843.1 - 2.4e-11 43.3 0.0 3.6e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KXS94843.1 - 2.7e-05 23.5 0.0 4.3e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KXS94843.1 - 0.00014 21.8 0.0 0.00027 20.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXS94843.1 - 0.00043 19.9 0.0 0.00067 19.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 KXS94843.1 - 0.012 15.1 0.2 0.084 12.3 0.2 2.3 1 1 0 1 1 1 0 short chain dehydrogenase NAD_binding_4 PF07993.12 KXS94843.1 - 0.057 12.6 0.2 1.1 8.4 0.2 2.3 1 1 0 1 1 1 0 Male sterility protein Peptidase_C15 PF01470.17 KXS94844.1 - 0.00091 19.5 0.0 0.14 12.3 0.0 2.2 2 0 0 2 2 2 2 Pyroglutamyl peptidase CENP-F_leu_zip PF10473.9 KXS94845.1 - 0.0031 17.5 0.8 0.0052 16.8 0.8 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Transcrip_act PF04949.13 KXS94845.1 - 0.011 15.7 0.4 0.017 15.0 0.4 1.2 1 0 0 1 1 1 0 Transcriptional activator APG6_N PF17675.1 KXS94845.1 - 0.015 15.8 0.3 0.027 15.0 0.3 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region Takusan PF04822.13 KXS94845.1 - 0.042 13.7 2.0 0.083 12.8 2.0 1.4 1 0 0 1 1 1 0 Takusan DUF2205 PF10224.9 KXS94845.1 - 0.072 13.1 0.4 0.16 12.0 0.4 1.5 1 0 0 1 1 1 0 Short coiled-coil protein DUF4164 PF13747.6 KXS94845.1 - 0.52 10.6 4.1 1.4 9.3 4.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Sec23_trunk PF04811.15 KXS94846.1 - 2.2e-69 233.7 0.0 3.8e-69 232.9 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KXS94846.1 - 7.1e-25 86.8 0.1 2.7e-24 85.0 0.0 2.1 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KXS94846.1 - 5e-18 65.6 0.0 1.3e-17 64.3 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KXS94846.1 - 9.9e-16 57.5 5.0 1.7e-15 56.7 5.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KXS94846.1 - 3.1e-08 33.4 0.0 6.6e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 KXS94846.1 - 0.02 14.3 0.2 0.041 13.3 0.2 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain NTP_transf_5 PF14907.6 KXS94847.1 - 0.071 12.7 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised nucleotidyltransferase Glyco_hydro_72 PF03198.14 KXS94848.1 - 2.8e-129 430.9 3.7 3.5e-129 430.6 3.7 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 KXS94848.1 - 2e-24 86.1 3.4 4.8e-24 84.8 3.4 1.7 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.18 KXS94848.1 - 0.0042 16.5 0.3 0.0089 15.5 0.3 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) IBR PF01485.21 KXS94849.1 - 1.6e-10 41.0 30.7 4.7e-07 29.9 3.2 4.2 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain DUF2431 PF10354.9 KXS94850.1 - 1.2e-67 227.3 0.0 1.6e-67 227.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) Oxidored_FMN PF00724.20 KXS94852.1 - 6.9e-82 275.4 0.0 7.8e-82 275.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 KXS94852.1 - 0.0037 16.7 0.2 5 6.5 0.0 2.9 1 1 2 3 3 3 2 Xylose isomerase-like TIM barrel DUF1479 PF07350.12 KXS94853.1 - 1.6e-74 251.2 0.1 1.8e-74 251.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) RRM_1 PF00076.22 KXS94854.1 - 2.5e-31 107.3 0.1 2.2e-14 53.0 0.0 4.2 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXS94854.1 - 4.2e-05 23.3 0.0 0.36 10.7 0.0 3.4 3 0 0 3 3 3 3 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KXS94854.1 - 0.051 13.6 0.0 0.39 10.7 0.0 2.4 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Sulfotransfer_4 PF17784.1 KXS94855.1 - 8.5e-48 163.0 0.0 1e-47 162.7 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KXS94855.1 - 3.9e-09 37.2 1.3 1.6e-07 32.0 1.3 2.2 1 1 0 1 1 1 1 Sulfotransferase family NDUF_B12 PF08122.12 KXS94855.1 - 0.21 11.6 2.8 0.69 10.0 0.1 2.9 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B12 subunit family Plasmid_RAQPRD PF09686.10 KXS94856.1 - 0.032 14.4 0.1 0.079 13.2 0.0 1.6 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Bac_rhamnosid6H PF17389.2 KXS94857.1 - 4.1e-12 46.0 0.2 8.4e-12 45.0 0.2 1.4 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 KXS94857.1 - 6.4e-05 22.7 0.0 0.00014 21.6 0.0 1.5 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Bac_rhamnosid PF05592.11 KXS94857.1 - 0.0056 16.6 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain GDE_C PF06202.14 KXS94857.1 - 0.025 13.5 3.5 0.048 12.6 1.8 2.2 2 1 0 2 2 2 0 Amylo-alpha-1,6-glucosidase Trehalase PF01204.18 KXS94857.1 - 0.034 13.0 1.1 0.048 12.5 1.1 1.1 1 0 0 1 1 1 0 Trehalase SLT PF01464.20 KXS94859.1 - 0.00081 19.0 0.0 0.0019 17.9 0.0 1.6 1 1 0 1 1 1 1 Transglycosylase SLT domain STI1 PF17830.1 KXS94859.1 - 0.16 11.9 1.1 0.61 10.1 0.2 2.4 3 0 0 3 3 3 0 STI1 domain Abhydrolase_6 PF12697.7 KXS94860.1 - 2.2e-09 38.3 0.3 2.6e-09 38.0 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 KXS94860.1 - 0.033 13.1 0.0 0.041 12.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KXS94860.1 - 0.049 12.9 0.0 0.55 9.5 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 CorA PF01544.18 KXS94861.1 - 8.3e-07 28.6 6.5 3.7e-06 26.5 4.8 2.3 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein Cas1_AcylT PF07779.12 KXS94862.1 - 8.8e-90 301.9 16.5 2.2e-89 300.5 16.5 1.5 1 1 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p RTA1 PF04479.13 KXS94863.1 - 1.2e-62 211.2 3.6 1.2e-62 211.2 3.6 1.5 2 0 0 2 2 2 1 RTA1 like protein ABC_tran PF00005.27 KXS94864.1 - 2.3e-73 245.2 0.0 5.7e-37 127.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KXS94864.1 - 5.4e-62 209.9 14.9 9.8e-38 130.4 5.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KXS94864.1 - 2.6e-11 43.4 0.1 0.03 13.8 0.0 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KXS94864.1 - 4e-10 40.0 0.1 0.0069 16.2 0.0 4.2 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KXS94864.1 - 5.6e-10 39.9 1.7 0.00066 20.1 0.0 3.7 4 0 0 4 4 3 2 AAA ATPase domain AAA_29 PF13555.6 KXS94864.1 - 1.4e-09 37.5 0.0 0.00068 19.3 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KXS94864.1 - 1.6e-08 35.0 0.0 0.016 15.5 0.0 3.5 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KXS94864.1 - 1.5e-07 31.4 0.0 0.0016 18.3 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 KXS94864.1 - 5.8e-07 30.2 0.2 0.0097 16.4 0.1 2.3 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 KXS94864.1 - 7.2e-07 29.3 0.0 0.025 14.5 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_15 PF13175.6 KXS94864.1 - 1.1e-06 28.6 0.0 0.0094 15.7 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 KXS94864.1 - 1.5e-06 28.3 0.0 0.049 13.6 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KXS94864.1 - 1.9e-06 27.8 0.0 0.039 13.7 0.0 3.1 2 1 0 2 2 2 2 AAA domain ABC_ATPase PF09818.9 KXS94864.1 - 8e-06 24.9 0.9 0.076 11.8 0.0 3.7 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_25 PF13481.6 KXS94864.1 - 0.00011 21.8 2.3 0.82 9.2 0.0 3.5 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KXS94864.1 - 0.00019 21.6 0.2 0.6 10.3 0.0 3.9 4 0 0 4 4 4 1 AAA domain SbcCD_C PF13558.6 KXS94864.1 - 0.00049 20.3 0.6 0.43 10.8 0.5 3.7 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit G-alpha PF00503.20 KXS94864.1 - 0.0011 18.1 0.0 1.3 8.1 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_7 PF12775.7 KXS94864.1 - 0.0014 18.2 0.0 1 8.8 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region Zeta_toxin PF06414.12 KXS94864.1 - 0.0017 17.7 0.0 0.78 9.0 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.6 KXS94864.1 - 0.0027 18.2 0.0 0.96 10.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 KXS94864.1 - 0.0045 17.1 0.0 3.3 7.8 0.0 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_14 PF13173.6 KXS94864.1 - 0.0072 16.4 0.0 5 7.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 KXS94864.1 - 0.0082 15.8 0.0 2.4 7.7 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_28 PF13521.6 KXS94864.1 - 0.0087 16.3 0.5 4.5 7.5 0.2 2.9 2 1 1 3 3 2 1 AAA domain RNA_helicase PF00910.22 KXS94864.1 - 0.013 15.9 0.0 8.7 6.8 0.0 2.6 2 0 0 2 2 2 0 RNA helicase IstB_IS21 PF01695.17 KXS94864.1 - 0.019 14.7 0.5 31 4.2 0.0 3.8 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_24 PF13479.6 KXS94864.1 - 0.024 14.3 0.3 7.3 6.3 0.2 2.5 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KXS94864.1 - 0.027 14.6 0.0 5.6 7.1 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 KXS94864.1 - 0.06 13.1 0.0 1 9.1 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NACHT PF05729.12 KXS94864.1 - 0.075 13.0 0.8 7.8 6.4 0.1 2.9 3 0 0 3 3 2 0 NACHT domain AAA PF00004.29 KXS94864.1 - 0.094 13.1 0.1 13 6.2 0.0 3.5 4 0 0 4 4 2 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KXS94864.1 - 0.094 12.1 0.0 18 4.6 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 KXS94864.1 - 0.12 11.5 0.1 9 5.4 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain ATPase_2 PF01637.18 KXS94864.1 - 0.13 12.1 0.1 4.9 7.0 0.1 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea cobW PF02492.19 KXS94864.1 - 0.14 11.8 0.0 1.8 8.1 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 KXS94864.1 - 0.21 12.0 0.3 24 5.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain DUF4366 PF14283.6 KXS94865.1 - 0.18 11.8 0.0 0.26 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF3149 PF11346.8 KXS94865.1 - 0.42 10.3 7.4 1.3 8.8 6.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) ketoacyl-synt PF00109.26 KXS94867.1 - 2.8e-62 210.6 0.2 4.6e-62 209.9 0.2 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KXS94867.1 - 1.5e-48 166.0 0.0 2.4e-48 165.3 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXS94867.1 - 1.5e-36 125.0 0.5 3.1e-36 124.0 0.5 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 KXS94867.1 - 2.9e-23 82.6 0.0 8.2e-23 81.1 0.0 1.8 1 0 0 1 1 1 1 Polyketide synthase dehydratase SAT PF16073.5 KXS94867.1 - 2.4e-20 73.3 1.9 2.3e-18 66.8 0.0 3.0 3 0 0 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Thioesterase PF00975.20 KXS94867.1 - 2.3e-17 63.9 0.0 8.5e-17 62.0 0.0 2.0 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.25 KXS94867.1 - 4e-15 55.9 0.5 9.8e-07 29.0 0.1 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 KXS94867.1 - 2.8e-05 24.6 0.0 8.2e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 KXS94867.1 - 0.079 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain SARAF PF06682.12 KXS94869.1 - 0.011 15.4 0.0 0.011 15.4 0.0 1.9 2 1 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis DUF5082 PF16888.5 KXS94871.1 - 0.0034 17.7 16.6 0.0034 17.7 16.6 3.3 2 1 2 4 4 4 1 Domain of unknown function (DUF5082) GIT_CC PF16559.5 KXS94871.1 - 1.7 8.6 24.6 0.37 10.7 2.0 5.0 3 2 3 6 6 6 0 GIT coiled-coil Rho guanine nucleotide exchange factor BRE1 PF08647.11 KXS94871.1 - 3.5 7.8 40.6 0.11 12.6 1.8 4.4 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase Ax_dynein_light PF10211.9 KXS94871.1 - 4.4 7.2 38.7 0.094 12.6 10.1 3.3 2 1 1 3 3 3 0 Axonemal dynein light chain FAM76 PF16046.5 KXS94871.1 - 5.4 6.3 31.6 0.69 9.2 17.8 2.4 1 1 1 2 2 2 0 FAM76 protein MAD PF05557.13 KXS94871.1 - 5.7 5.2 42.9 0.14 10.4 21.2 2.1 1 1 1 2 2 2 0 Mitotic checkpoint protein Mito_fiss_reg PF05308.11 KXS94872.1 - 1.2 9.2 8.0 1.5 8.9 8.0 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator Aminotran_1_2 PF00155.21 KXS94876.1 - 6.6e-44 150.6 0.0 9.3e-44 150.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KXS94876.1 - 4.6e-06 25.4 0.0 7e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 KXS94876.1 - 0.00017 21.0 0.0 0.00055 19.3 0.0 1.7 2 0 0 2 2 2 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KXS94876.1 - 0.00094 18.2 0.0 0.0018 17.3 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Alliinase_C PF04864.13 KXS94876.1 - 0.081 11.8 0.2 0.21 10.4 0.2 1.6 1 1 0 1 1 1 0 Allinase UCH PF00443.29 KXS94877.1 - 6.7e-53 179.8 0.0 9.7e-53 179.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXS94877.1 - 2.7e-17 63.4 0.8 4.4e-15 56.1 0.8 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 KXS94877.1 - 1.5e-05 25.4 0.0 6.1e-05 23.5 0.0 2.1 1 0 0 1 1 1 1 Rhodanese-like domain MIF4G PF02854.19 KXS94877.1 - 0.075 12.7 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 MIF4G domain HTH_26 PF13443.6 KXS94877.1 - 0.16 12.4 0.0 1.1 9.7 0.0 2.2 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain CpXC PF14353.6 KXS94877.1 - 0.25 11.4 1.0 1.2 9.2 1.0 2.1 1 1 0 1 1 1 0 CpXC protein Rad21_Rec8_N PF04825.13 KXS94878.1 - 1.8e-20 73.1 0.1 3.6e-20 72.2 0.1 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KXS94878.1 - 3.7e-06 26.1 0.0 8e-06 25.0 0.0 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein Kinesin PF00225.23 KXS94879.1 - 3e-112 374.9 0.4 3e-112 374.9 0.4 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KXS94879.1 - 5e-28 97.9 0.0 6.4e-27 94.3 0.0 3.0 2 0 0 2 2 2 1 Microtubule binding Microtub_bind PF13931.6 KXS94879.1 - 7.3e-06 26.4 0.4 7.3e-06 26.4 0.4 5.2 4 1 1 5 5 5 1 Kinesin-associated microtubule-binding VASP_tetra PF08776.11 KXS94879.1 - 0.061 12.9 1.9 1.1 8.9 0.5 2.7 2 0 0 2 2 2 0 VASP tetramerisation domain AAA_24 PF13479.6 KXS94879.1 - 1.5 8.5 6.3 20 4.8 0.0 3.9 4 0 0 4 4 4 0 AAA domain UPF0183 PF03676.14 KXS94880.1 - 1.5e-50 172.7 0.0 2e-36 126.2 0.0 2.6 2 1 0 2 2 2 2 Uncharacterised protein family (UPF0183) F-actin_cap_A PF01267.17 KXS94881.1 - 2.4e-94 315.7 0.0 2.7e-94 315.5 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit CdiI_2 PF18593.1 KXS94881.1 - 0.0064 17.1 0.0 0.064 13.9 0.0 2.2 2 0 0 2 2 2 1 CdiI immunity protein DUF512 PF04459.12 KXS94881.1 - 0.069 12.4 0.0 1.6 8.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF512) SQS_PSY PF00494.19 KXS94882.1 - 3.3e-34 118.6 0.0 4.8e-34 118.1 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase CxC7 PF18866.1 KXS94884.1 - 0.14 12.3 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 CxC7 like cysteine cluster associated with KDZ transposases PET PF06297.14 KXS94885.1 - 0.66 10.3 5.2 0.33 11.3 2.4 2.0 2 0 0 2 2 2 0 PET Domain Activator-TraM PF11657.8 KXS94885.1 - 1.2 8.9 11.9 0.7 9.7 7.5 2.7 1 1 1 2 2 2 0 Transcriptional activator TraM DUF334 PF03904.13 KXS94885.1 - 3.7 7.0 11.3 7.1 6.1 11.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Ribonuc_2-5A PF06479.12 KXS94886.1 - 8.1e-43 145.6 0.1 1.5e-42 144.7 0.1 1.5 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.25 KXS94886.1 - 1.4e-37 129.5 0.0 6.5e-37 127.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS94886.1 - 3e-21 75.9 0.0 6.9e-21 74.7 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.21 KXS94886.1 - 1.6e-05 24.6 0.0 0.025 14.5 0.0 2.8 2 0 0 2 2 2 2 PQQ enzyme repeat Pkinase_fungal PF17667.1 KXS94886.1 - 9.9e-05 21.3 0.0 0.0077 15.0 0.0 2.3 2 0 0 2 2 2 1 Fungal protein kinase PQQ_2 PF13360.6 KXS94886.1 - 0.00012 21.8 0.1 0.00041 20.0 0.1 1.7 1 1 0 1 1 1 1 PQQ-like domain APH PF01636.23 KXS94886.1 - 0.015 15.3 0.3 0.015 15.3 0.3 2.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 KXS94886.1 - 0.069 12.5 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KXS94886.1 - 0.093 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL AAA_5 PF07728.14 KXS94887.1 - 7.7e-123 404.9 3.4 1e-21 77.4 0.0 9.8 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 KXS94887.1 - 1.5e-50 169.8 7.1 2.5e-22 79.1 0.4 5.8 5 0 0 5 5 4 3 Midasin AAA lid domain AAA_lid_5 PF17865.1 KXS94887.1 - 1e-30 106.0 0.1 4e-29 100.8 0.2 3.0 2 0 0 2 2 2 1 Midasin AAA lid domain AAA_3 PF07726.11 KXS94887.1 - 6.9e-29 100.4 0.0 6.4e-09 35.8 0.0 8.3 8 0 0 8 8 7 2 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 KXS94887.1 - 4.8e-28 98.2 3.2 0.00025 21.4 0.0 7.6 7 0 0 7 7 6 6 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KXS94887.1 - 7.4e-27 94.0 2.8 1.3e-05 24.8 0.1 6.7 6 0 0 6 6 6 6 P-loop containing dynein motor region AAA_16 PF13191.6 KXS94887.1 - 2.6e-25 89.8 29.5 1.2e-06 29.0 0.2 10.7 9 1 0 9 9 8 6 AAA ATPase domain Dynein_heavy PF03028.15 KXS94887.1 - 1.4e-22 80.0 0.0 0.0039 17.3 0.0 7.4 8 0 0 8 8 7 4 Dynein heavy chain region D6 P-loop domain Sigma54_activat PF00158.26 KXS94887.1 - 4.1e-22 78.6 0.1 0.0085 15.8 0.0 6.3 6 0 0 6 6 6 5 Sigma-54 interaction domain AAA_18 PF13238.6 KXS94887.1 - 3.3e-21 76.2 1.7 0.0029 18.2 0.0 8.5 8 0 0 8 8 8 4 AAA domain AAA_22 PF13401.6 KXS94887.1 - 7.3e-19 68.4 1.7 0.0055 17.0 0.0 8.6 7 0 0 7 7 7 3 AAA domain AAA_6 PF12774.7 KXS94887.1 - 1e-18 67.4 5.2 0.003 16.6 0.0 8.0 8 0 0 8 8 8 4 Hydrolytic ATP binding site of dynein motor region TsaE PF02367.17 KXS94887.1 - 1.5e-18 67.0 5.5 0.025 14.6 0.2 6.8 6 0 0 6 6 6 4 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KXS94887.1 - 1.6e-18 67.1 10.3 0.043 13.5 0.0 8.8 8 1 0 8 8 7 4 AAA domain T2SSE PF00437.20 KXS94887.1 - 1.4e-15 57.1 1.7 0.005 15.9 0.0 6.4 6 0 0 6 6 6 4 Type II/IV secretion system protein AAA_33 PF13671.6 KXS94887.1 - 7.7e-15 55.3 1.7 0.3 11.2 0.0 7.5 6 1 1 7 7 7 2 AAA domain Sigma54_activ_2 PF14532.6 KXS94887.1 - 2e-14 53.9 0.4 0.011 15.9 0.0 5.8 6 0 0 6 6 5 2 Sigma-54 interaction domain Zeta_toxin PF06414.12 KXS94887.1 - 1e-13 51.0 6.0 0.0083 15.4 0.1 7.4 6 1 1 7 7 7 4 Zeta toxin ABC_tran PF00005.27 KXS94887.1 - 1.7e-13 51.3 1.1 0.0021 18.6 0.0 6.9 6 0 0 6 6 6 3 ABC transporter AAA_14 PF13173.6 KXS94887.1 - 5.1e-13 49.2 0.0 0.022 14.8 0.0 7.2 8 0 0 8 8 6 2 AAA domain RNA_helicase PF00910.22 KXS94887.1 - 1.2e-12 48.1 2.6 0.12 12.8 0.0 6.7 6 0 0 6 6 6 2 RNA helicase NACHT PF05729.12 KXS94887.1 - 3e-12 46.8 7.7 0.22 11.4 0.0 6.9 7 0 0 7 7 5 3 NACHT domain RsgA_GTPase PF03193.16 KXS94887.1 - 8.2e-12 45.3 0.5 0.1 12.5 0.0 6.7 6 0 0 6 6 6 2 RsgA GTPase RuvB_N PF05496.12 KXS94887.1 - 8.3e-12 45.1 8.0 0.13 12.0 0.0 7.6 8 0 0 8 8 7 2 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 KXS94887.1 - 3.5e-11 43.6 6.3 1.2 9.5 0.1 7.5 6 0 0 6 6 6 2 AAA domain AAA_29 PF13555.6 KXS94887.1 - 1.9e-09 37.1 0.7 0.91 9.3 0.0 6.4 6 0 0 6 6 6 1 P-loop containing region of AAA domain Mg_chelatase PF01078.21 KXS94887.1 - 3.5e-09 36.3 3.8 4.1 6.7 0.0 8.6 8 1 0 8 8 8 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KXS94887.1 - 3.7e-09 36.5 1.3 2.5 7.8 0.0 6.5 6 0 0 6 6 6 1 IstB-like ATP binding protein Rad17 PF03215.15 KXS94887.1 - 6.1e-09 36.1 0.5 0.57 10.1 0.0 5.1 5 0 0 5 5 4 2 Rad17 P-loop domain AAA_25 PF13481.6 KXS94887.1 - 1.3e-08 34.7 9.3 0.37 10.3 0.2 6.3 5 0 0 5 5 5 2 AAA domain AAA_28 PF13521.6 KXS94887.1 - 1.7e-08 34.9 10.3 0.12 12.6 0.1 7.5 6 0 0 6 6 6 1 AAA domain NTPase_1 PF03266.15 KXS94887.1 - 1.1e-07 31.9 8.7 1.1 9.1 0.1 6.0 5 0 0 5 5 5 1 NTPase SRP54 PF00448.22 KXS94887.1 - 6.3e-06 26.0 10.2 0.28 10.8 0.0 5.6 6 0 0 6 6 5 2 SRP54-type protein, GTPase domain PduV-EutP PF10662.9 KXS94887.1 - 6.6e-06 25.9 3.0 0.022 14.5 0.1 5.3 6 0 0 6 6 6 1 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 KXS94887.1 - 7.7e-06 25.8 4.0 15 5.3 0.0 6.0 6 1 0 6 6 6 0 AAA domain DUF815 PF05673.13 KXS94887.1 - 7.8e-06 25.2 0.8 6 6.0 0.0 5.5 6 0 0 6 6 6 0 Protein of unknown function (DUF815) TniB PF05621.11 KXS94887.1 - 9.1e-06 25.2 0.2 3.1 7.2 0.0 4.5 4 0 0 4 4 4 0 Bacterial TniB protein Viral_helicase1 PF01443.18 KXS94887.1 - 1.8e-05 24.6 0.7 18 5.0 0.0 6.0 6 0 0 6 6 5 0 Viral (Superfamily 1) RNA helicase TIP49 PF06068.13 KXS94887.1 - 5e-05 22.7 2.0 2.2 7.4 0.0 5.7 6 0 0 6 6 6 1 TIP49 P-loop domain ResIII PF04851.15 KXS94887.1 - 9.3e-05 22.5 1.6 3.2 7.7 0.0 4.9 5 0 0 5 5 5 0 Type III restriction enzyme, res subunit Roc PF08477.13 KXS94887.1 - 0.00023 21.4 2.9 8.7 6.6 0.1 5.7 5 0 0 5 5 5 0 Ras of Complex, Roc, domain of DAPkinase Thymidylate_kin PF02223.17 KXS94887.1 - 0.0005 19.8 1.7 2.5 7.8 0.1 5.7 5 0 0 5 5 4 1 Thymidylate kinase AAA_17 PF13207.6 KXS94887.1 - 0.00084 19.8 9.0 2.1 8.8 0.0 5.9 6 0 0 6 6 5 1 AAA domain ATPase PF06745.13 KXS94887.1 - 0.0013 18.1 1.0 9.4 5.5 0.0 4.9 5 0 0 5 5 5 0 KaiC MMR_HSR1 PF01926.23 KXS94887.1 - 0.0022 18.0 7.0 44 4.2 0.0 6.6 7 0 0 7 7 6 0 50S ribosome-binding GTPase DEAD PF00270.29 KXS94887.1 - 0.0026 17.6 0.1 1.8 8.3 0.0 3.8 3 0 0 3 3 3 1 DEAD/DEAH box helicase ATPase_2 PF01637.18 KXS94887.1 - 0.0026 17.7 0.0 11 5.8 0.0 4.7 5 0 0 5 5 4 0 ATPase domain predominantly from Archaea KAP_NTPase PF07693.14 KXS94887.1 - 0.0029 16.9 0.0 7.2 5.7 0.0 4.6 5 0 0 5 5 4 0 KAP family P-loop domain dNK PF01712.19 KXS94887.1 - 0.003 17.4 7.2 20 5.0 0.0 5.7 6 0 0 6 6 6 0 Deoxynucleoside kinase VWA_2 PF13519.6 KXS94887.1 - 0.0053 17.4 0.2 0.032 14.9 0.2 2.5 1 0 0 1 1 1 1 von Willebrand factor type A domain PRK PF00485.18 KXS94887.1 - 0.0054 16.5 1.2 11 5.7 0.0 4.8 5 0 0 5 5 4 0 Phosphoribulokinase / Uridine kinase family Bac_DnaA PF00308.18 KXS94887.1 - 0.0057 16.5 1.0 21 4.8 0.0 4.8 6 0 0 6 6 4 0 Bacterial dnaA protein AAA_23 PF13476.6 KXS94887.1 - 0.01 16.4 30.4 0.27 11.7 0.0 7.8 7 0 0 7 7 6 0 AAA domain KTI12 PF08433.10 KXS94887.1 - 0.017 14.6 0.1 33 3.8 0.0 4.7 5 0 0 5 5 5 0 Chromatin associated protein KTI12 cobW PF02492.19 KXS94887.1 - 0.018 14.7 11.7 0.32 10.6 0.1 5.7 6 0 0 6 6 6 0 CobW/HypB/UreG, nucleotide-binding domain AAA_9 PF12781.7 KXS94887.1 - 0.02 14.0 0.0 0.31 10.1 0.0 3.1 4 0 0 4 4 2 0 ATP-binding dynein motor region MeaB PF03308.16 KXS94887.1 - 0.048 12.6 5.5 4.2 6.3 0.1 4.2 5 0 0 5 5 4 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PhoH PF02562.16 KXS94887.1 - 0.13 11.7 5.7 27 4.1 0.0 4.6 5 0 0 5 5 5 0 PhoH-like protein FtsK_SpoIIIE PF01580.18 KXS94887.1 - 0.16 11.3 2.6 44 3.3 0.0 4.2 4 0 0 4 4 4 0 FtsK/SpoIIIE family G-alpha PF00503.20 KXS94887.1 - 0.22 10.7 3.1 13 4.8 0.0 4.0 4 0 0 4 4 3 0 G-protein alpha subunit ATP_bind_1 PF03029.17 KXS94887.1 - 0.55 10.0 17.7 2.6 7.7 0.2 6.1 7 0 0 7 7 6 0 Conserved hypothetical ATP binding protein CbiA PF01656.23 KXS94887.1 - 0.62 10.1 12.1 12 6.0 0.0 5.5 5 0 0 5 5 5 0 CobQ/CobB/MinD/ParA nucleotide binding domain APS_kinase PF01583.20 KXS94887.1 - 0.72 9.7 5.4 23 4.9 0.0 4.3 5 0 0 5 5 3 0 Adenylylsulphate kinase zf-CSL PF05207.13 KXS94888.1 - 2.1e-18 65.8 0.4 3.1e-18 65.2 0.4 1.3 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 KXS94888.1 - 5.6e-11 42.4 0.2 8.2e-11 41.9 0.2 1.3 1 0 0 1 1 1 1 DnaJ domain Sugar_tr PF00083.24 KXS94889.1 - 2.8e-108 362.7 24.4 3.5e-108 362.4 24.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS94889.1 - 9e-19 67.6 25.2 1.7e-12 46.9 5.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Herpes_US9 PF06072.11 KXS94889.1 - 0.59 10.0 4.2 0.5 10.3 0.2 2.9 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 CLZ PF16526.5 KXS94893.1 - 0.0058 17.0 1.9 0.3 11.5 0.6 2.0 1 1 1 2 2 2 2 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FlpD PF02662.16 KXS94893.1 - 0.016 15.2 0.3 0.021 14.8 0.3 1.2 1 1 0 1 1 1 0 Methyl-viologen-reducing hydrogenase, delta subunit DUF1173 PF06666.11 KXS94893.1 - 0.023 13.7 0.6 0.026 13.5 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1173) ADIP PF11559.8 KXS94893.1 - 0.071 13.2 1.6 0.085 12.9 1.6 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding HAUS-augmin3 PF14932.6 KXS94893.1 - 0.14 11.7 2.8 0.19 11.3 2.8 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 MerR-DNA-bind PF09278.11 KXS94893.1 - 0.7 10.5 4.2 6.3 7.4 0.3 2.1 1 1 1 2 2 2 0 MerR, DNA binding DUF4094 PF13334.6 KXS94893.1 - 0.81 10.1 3.6 3.1 8.3 3.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) Dynamin_N PF00350.23 KXS94894.1 - 3e-09 37.2 1.4 2.7e-08 34.0 0.0 2.9 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KXS94894.1 - 0.00051 20.1 0.4 0.022 14.8 0.4 2.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 KXS94894.1 - 0.0018 18.4 0.9 0.11 12.6 0.0 3.1 2 1 1 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 KXS94894.1 - 0.027 14.4 0.8 0.52 10.2 0.0 3.1 3 0 0 3 3 3 0 RsgA GTPase Peptidase_S66 PF02016.15 KXS94894.1 - 0.03 14.4 0.1 0.22 11.7 0.0 2.5 2 0 0 2 2 2 0 LD-carboxypeptidase N-terminal domain Nexin_C PF08628.12 KXS94894.1 - 0.046 14.3 0.0 5.5 7.6 0.0 2.8 2 0 0 2 2 2 0 Sorting nexin C terminal DUF4665 PF15679.5 KXS94894.1 - 1.1 10.0 8.1 2.6 8.7 0.5 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF4665) RhoGAP PF00620.27 KXS94895.1 - 4.2e-39 133.8 0.1 1e-38 132.5 0.1 1.7 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 KXS94895.1 - 7.3e-14 52.2 0.0 2.4e-13 50.5 0.0 1.9 2 0 0 2 2 2 1 PH domain PX PF00787.24 KXS94895.1 - 0.085 12.8 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 PX domain PH_8 PF15409.6 KXS94895.1 - 0.13 12.6 0.0 0.4 11.0 0.0 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain MCM_bind PF09739.9 KXS94895.1 - 0.58 8.5 5.9 1.1 7.6 5.9 1.3 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor But2 PF09792.9 KXS94896.1 - 4.5e-52 176.2 1.0 4.5e-52 176.2 1.0 2.3 2 0 0 2 2 2 1 Ubiquitin 3 binding protein But2 C-terminal domain Glyco_hydro_17 PF00332.18 KXS94896.1 - 0.00052 19.7 2.4 0.00082 19.1 1.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 Orn_Arg_deC_N PF02784.16 KXS94897.1 - 2.5e-82 276.0 0.0 3.3e-82 275.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KXS94897.1 - 5.6e-19 68.2 0.0 8.8e-19 67.6 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.24 KXS94897.1 - 0.0012 18.3 0.0 0.0022 17.5 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Ribosomal_L12 PF00542.19 KXS94898.1 - 5.2e-20 71.6 8.4 2.6e-19 69.3 7.3 2.1 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 KXS94898.1 - 1e-14 54.0 5.0 1.2e-14 53.7 2.0 2.7 2 0 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain Fungal_trans_2 PF11951.8 KXS94899.1 - 1.8e-11 43.5 0.1 2.9e-11 42.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PARM PF17061.5 KXS94899.1 - 0.053 13.7 7.6 0.082 13.0 7.6 1.3 1 0 0 1 1 1 0 PARM CCDC85 PF10226.9 KXS94899.1 - 0.12 12.1 0.1 0.12 12.1 0.1 1.9 2 0 0 2 2 2 0 CCDC85 family 40S_SA_C PF16122.5 KXS94899.1 - 0.15 13.4 2.2 0.27 12.6 2.2 1.3 1 0 0 1 1 1 0 40S ribosomal protein SA C-terminus FHA PF00498.26 KXS94901.1 - 6.6e-16 58.4 0.0 1.2e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 KXS94901.1 - 3.2e-13 49.2 5.6 5.5e-13 48.4 5.6 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 KXS94901.1 - 9.5e-07 29.1 8.7 1.7e-06 28.2 8.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KXS94901.1 - 0.00025 20.8 7.3 0.00042 20.1 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Yop-YscD_cpl PF16697.5 KXS94901.1 - 0.00032 20.9 0.0 0.00062 20.0 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-RING_5 PF14634.6 KXS94901.1 - 0.001 18.9 5.8 0.0017 18.2 5.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KXS94901.1 - 0.0087 16.3 7.4 0.019 15.2 7.4 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KXS94901.1 - 0.016 15.2 2.5 0.028 14.5 2.5 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KXS94901.1 - 0.03 14.2 5.3 0.051 13.5 5.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXS94901.1 - 0.06 13.4 7.1 0.11 12.5 7.1 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KXS94901.1 - 0.08 12.8 7.4 0.15 11.9 7.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 KXS94901.1 - 0.094 13.0 5.4 0.18 12.1 5.4 1.5 1 0 0 1 1 1 0 RING-like domain Vps39_2 PF10367.9 KXS94901.1 - 0.23 11.9 0.9 0.43 11.0 0.9 1.4 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 Zn_ribbon_17 PF17120.5 KXS94901.1 - 0.48 10.1 4.8 0.9 9.2 4.8 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 KXS94901.1 - 0.5 10.3 5.3 1.1 9.2 5.3 1.6 1 0 0 1 1 1 0 PHD-finger SRP-alpha_N PF04086.13 KXS94901.1 - 2 8.3 10.4 6.8 6.5 0.5 2.3 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal PhyH PF05721.13 KXS94902.1 - 9.5e-28 97.9 0.0 1.5e-27 97.3 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) RCC1_2 PF13540.6 KXS94903.1 - 1.6e-12 46.9 7.1 0.00021 21.0 0.2 5.8 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 KXS94903.1 - 3.2e-10 40.5 0.6 3.3e-05 24.4 0.2 4.8 4 0 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.7 KXS94903.1 - 7.6e-06 25.7 0.1 1.5e-05 24.8 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS94903.1 - 0.13 12.2 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 F-box domain Elongin_A PF06881.11 KXS94903.1 - 0.17 12.4 0.0 0.38 11.3 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box_4 PF15966.5 KXS94903.1 - 0.2 11.6 0.0 0.42 10.5 0.0 1.5 1 0 0 1 1 1 0 F-box DUF3006 PF11213.8 KXS94903.1 - 0.2 11.9 0.0 0.47 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3006) Glyco_hydro_43 PF04616.14 KXS94904.1 - 8e-33 114.0 0.2 9.8e-33 113.7 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 adh_short PF00106.25 KXS94905.1 - 7.2e-22 77.8 0.0 3.7e-12 46.1 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXS94905.1 - 1.1e-09 38.2 0.0 0.00046 19.8 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS94905.1 - 0.0027 17.6 0.0 0.0053 16.7 0.0 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KXS94905.1 - 0.003 17.5 0.0 0.0045 16.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KXS94905.1 - 0.003 16.8 0.0 0.004 16.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF1776 PF08643.10 KXS94905.1 - 0.036 13.4 0.0 0.13 11.6 0.0 1.8 1 1 1 2 2 2 0 Fungal family of unknown function (DUF1776) bZIP_1 PF00170.21 KXS94908.1 - 3.9e-05 23.7 8.6 0.00014 21.9 8.6 1.9 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXS94908.1 - 0.0087 16.1 7.9 0.017 15.2 2.4 2.2 2 0 0 2 2 2 2 Basic region leucine zipper Cnn_1N PF07989.11 KXS94908.1 - 0.14 12.3 0.8 0.22 11.7 0.8 1.4 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 RasGEF PF00617.19 KXS94909.1 - 1.5e-60 204.4 0.7 3e-60 203.4 0.7 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KXS94909.1 - 4.8e-25 87.8 0.0 1.1e-24 86.7 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 KXS94909.1 - 2.6e-15 55.8 0.1 5.3e-15 54.8 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXS94909.1 - 3.8e-14 52.3 0.1 8.7e-14 51.1 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KXS94909.1 - 7.1e-13 48.0 0.1 1.6e-12 46.9 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 KXS94909.1 - 0.00021 21.3 0.0 0.00043 20.3 0.0 1.6 1 0 0 1 1 1 1 WW domain PG_binding_2 PF08823.11 KXS94910.1 - 0.017 15.4 0.3 4.7 7.6 0.0 2.5 2 0 0 2 2 2 0 Putative peptidoglycan binding domain F-box PF00646.33 KXS94910.1 - 0.077 12.9 0.1 0.23 11.4 0.0 1.8 2 0 0 2 2 2 0 F-box domain JmjN PF02375.17 KXS94910.1 - 0.092 12.7 0.0 0.58 10.2 0.0 2.2 2 0 0 2 2 2 0 jmjN domain PG_binding_2 PF08823.11 KXS94911.1 - 0.017 15.4 0.3 4.7 7.6 0.0 2.5 2 0 0 2 2 2 0 Putative peptidoglycan binding domain F-box PF00646.33 KXS94911.1 - 0.077 12.9 0.1 0.23 11.4 0.0 1.8 2 0 0 2 2 2 0 F-box domain JmjN PF02375.17 KXS94911.1 - 0.092 12.7 0.0 0.58 10.2 0.0 2.2 2 0 0 2 2 2 0 jmjN domain Oxidored_molyb PF00174.19 KXS94912.1 - 1.1e-54 184.7 0.0 1.9e-54 183.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KXS94912.1 - 3e-37 127.7 1.3 6.4e-37 126.6 1.3 1.6 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain FAD_binding_6 PF00970.24 KXS94912.1 - 2.5e-21 75.9 0.0 3.7e-09 36.8 0.0 2.5 1 1 0 2 2 2 2 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KXS94912.1 - 3.4e-20 72.7 0.0 4.6e-19 69.1 0.0 2.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 KXS94912.1 - 9.2e-14 51.4 0.1 2.6e-13 49.9 0.1 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Alpha-amylase PF00128.24 KXS94918.1 - 2.6e-101 339.6 0.0 3.7e-101 339.1 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 KXS94918.1 - 0.059 12.4 0.0 0.093 11.8 0.0 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain TauD PF02668.16 KXS94919.1 - 2.4e-48 165.2 0.6 2.9e-48 165.0 0.6 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF2243 PF10002.9 KXS94919.1 - 0.091 12.9 0.1 0.38 10.9 0.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2243) F-box PF00646.33 KXS94920.1 - 1.3e-06 28.1 0.3 1.3e-06 28.1 0.3 2.2 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 KXS94920.1 - 4.1e-05 23.4 1.0 0.00033 20.5 0.6 2.3 2 0 0 2 2 2 1 F-box-like Enamelin PF15362.6 KXS94920.1 - 0.35 9.1 0.0 0.47 8.7 0.0 1.0 1 0 0 1 1 1 0 Enamelin PRP38 PF03371.15 KXS94921.1 - 2.2e-57 193.7 0.0 2.6e-57 193.5 0.0 1.1 1 0 0 1 1 1 1 PRP38 family Terpene_synth_C PF03936.16 KXS94923.1 - 0.0054 16.1 0.0 0.0089 15.4 0.0 1.4 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain Aldo_ket_red PF00248.21 KXS94924.1 - 1.8e-13 50.4 0.0 2.7e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family AMP-binding PF00501.28 KXS94925.1 - 6.5e-99 331.4 0.0 7.8e-99 331.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXS94925.1 - 2.3e-13 50.9 0.2 4.7e-13 49.9 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PRD PF00874.20 KXS94925.1 - 0.051 13.9 0.1 0.096 13.0 0.1 1.4 1 0 0 1 1 1 0 PRD domain Abhydrolase_6 PF12697.7 KXS94926.1 - 1.9e-17 64.6 0.0 2.8e-17 64.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.12 KXS94926.1 - 0.0048 16.6 0.0 0.0081 15.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase Abhydrolase_5 PF12695.7 KXS94926.1 - 0.0093 15.7 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXS94926.1 - 0.023 14.4 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXS94926.1 - 0.03 13.6 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Radical_SAM PF04055.21 KXS94926.1 - 0.066 13.6 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 Radical SAM superfamily Lipase_2 PF01674.18 KXS94926.1 - 0.12 11.9 0.0 0.75 9.3 0.0 2.0 2 0 0 2 2 2 0 Lipase (class 2) EBP PF05241.12 KXS94927.1 - 3.2e-64 215.7 6.3 4.5e-64 215.2 6.3 1.2 1 0 0 1 1 1 1 Emopamil binding protein MFS_1 PF07690.16 KXS94928.1 - 7.2e-44 150.2 37.6 7.2e-44 150.2 37.6 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS94928.1 - 2.4e-13 49.8 10.9 2.4e-13 49.8 10.9 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter Complex1_LYR_2 PF13233.6 KXS94929.1 - 6.3e-22 78.1 0.6 1.3e-21 77.1 0.6 1.6 1 0 0 1 1 1 1 Complex1_LYR-like Fringe PF02434.16 KXS94929.1 - 2.8e-08 33.5 0.0 5.5e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Fringe-like PAN_4 PF14295.6 KXS94929.1 - 0.082 12.8 0.9 0.2 11.6 0.9 1.6 1 0 0 1 1 1 0 PAN domain Ytca PF17090.5 KXS94929.1 - 2.7 8.6 4.2 0.73 10.4 0.6 1.9 2 0 0 2 2 2 0 Uncharacterised protein family Retrotran_gag_2 PF14223.6 KXS94930.1 - 0.34 10.6 1.2 0.41 10.3 0.0 1.7 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type MIP PF00230.20 KXS94931.1 - 5.4e-46 157.1 16.8 7.2e-46 156.7 16.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein adh_short_C2 PF13561.6 KXS94932.1 - 4.3e-59 199.9 0.1 5.9e-59 199.5 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS94932.1 - 4.6e-50 169.8 0.0 7.6e-50 169.1 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS94932.1 - 2.3e-07 30.9 0.5 1.2e-06 28.6 0.5 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS94932.1 - 0.00013 21.6 0.1 0.00039 20.0 0.1 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXS94932.1 - 0.05 13.0 0.1 0.066 12.6 0.1 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase BTB PF00651.31 KXS94937.1 - 0.12 12.6 0.0 0.3 11.4 0.0 1.6 2 0 0 2 2 2 0 BTB/POZ domain ATG11 PF10377.9 KXS94938.1 - 6.9e-39 132.9 0.0 6.9e-39 132.9 0.0 4.6 5 0 0 5 5 5 1 Autophagy-related protein 11 APG17 PF04108.12 KXS94938.1 - 2.8e-05 23.4 19.3 0.00035 19.8 1.3 5.8 4 2 0 5 5 5 3 Autophagy protein Apg17 Baculo_F PF12259.8 KXS94938.1 - 0.13 10.7 10.8 0.033 12.7 1.3 2.5 2 0 0 2 2 2 0 Baculovirus F protein DUF4407 PF14362.6 KXS94938.1 - 1.2 8.4 88.0 0.028 13.8 8.5 5.6 5 1 2 7 7 7 0 Domain of unknown function (DUF4407) HP0268 PF18618.1 KXS94938.1 - 5 7.6 5.8 5.3 7.5 0.9 3.0 2 0 0 2 2 2 0 HP0268 DUF948 PF06103.11 KXS94938.1 - 8.2 6.8 22.3 0.37 11.1 1.1 6.8 6 1 1 7 7 7 0 Bacterial protein of unknown function (DUF948) ANAPC1 PF12859.7 KXS94940.1 - 0.31 11.6 6.9 0.68 10.5 6.0 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 1 SWIRM-assoc_2 PF16496.5 KXS94940.1 - 0.46 9.3 7.2 0.55 9.0 7.2 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Plasmodium_Vir PF05795.11 KXS94940.1 - 2 7.7 5.6 2.7 7.3 5.6 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Methyltransf_11 PF08241.12 KXS94941.1 - 1.9e-12 47.7 0.0 3.7e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS94941.1 - 5.6e-12 46.2 0.0 3.5e-11 43.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXS94941.1 - 1.3e-11 44.7 0.0 2.3e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS94941.1 - 1.9e-10 41.4 0.0 3.2e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS94941.1 - 4.2e-10 39.6 0.0 1.4e-09 37.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXS94941.1 - 2.7e-07 30.2 0.0 8.4e-07 28.6 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KXS94941.1 - 0.00045 19.8 0.0 0.0013 18.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_32 PF13679.6 KXS94941.1 - 0.00076 19.5 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KXS94941.1 - 0.0035 16.7 0.0 0.0053 16.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DREV PF05219.12 KXS94941.1 - 0.0062 15.7 0.0 0.055 12.5 0.0 2.0 1 1 0 2 2 2 1 DREV methyltransferase PrmA PF06325.13 KXS94941.1 - 0.01 15.3 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.20 KXS94941.1 - 0.022 13.8 0.0 0.042 12.9 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase adh_short PF00106.25 KXS94941.1 - 0.031 13.7 0.0 0.17 11.3 0.0 1.9 1 1 1 2 2 2 0 short chain dehydrogenase Methyltransf_16 PF10294.9 KXS94941.1 - 0.044 13.5 0.0 0.11 12.2 0.0 1.5 1 1 0 1 1 1 0 Lysine methyltransferase PCMT PF01135.19 KXS94941.1 - 0.078 12.7 0.0 0.17 11.6 0.0 1.5 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 3HCDH_N PF02737.18 KXS94941.1 - 0.14 12.0 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HTH_38 PF13936.6 KXS94943.1 - 1e-14 54.0 9.7 0.059 13.2 0.0 6.3 6 0 0 6 6 6 4 Helix-turn-helix domain HTH_23 PF13384.6 KXS94943.1 - 3.3e-11 42.6 12.9 0.001 18.8 0.1 6.2 6 0 0 6 6 6 2 Homeodomain-like domain HTH_7 PF02796.15 KXS94943.1 - 1.2e-10 41.3 0.1 0.0043 17.1 0.0 4.5 4 0 0 4 4 4 2 Helix-turn-helix domain of resolvase Sigma70_r4_2 PF08281.12 KXS94943.1 - 2.3e-10 40.0 3.2 0.026 14.2 0.0 5.0 5 0 0 5 5 5 4 Sigma-70, region 4 GerE PF00196.19 KXS94943.1 - 1.3e-07 31.0 0.0 0.45 10.1 0.0 4.8 5 0 0 5 5 5 2 Bacterial regulatory proteins, luxR family HTH_28 PF13518.6 KXS94943.1 - 3.2e-06 27.2 1.1 0.33 11.1 0.0 4.4 4 0 0 4 4 4 1 Helix-turn-helix domain GcrA PF07750.11 KXS94943.1 - 9.6e-06 26.1 1.2 0.031 14.7 0.0 3.7 3 1 1 4 4 4 1 GcrA cell cycle regulator Sigma70_r4 PF04545.16 KXS94943.1 - 1.2e-05 24.7 6.2 0.08 12.5 0.1 4.8 5 0 0 5 5 5 2 Sigma-70, region 4 Myb_DNA-binding PF00249.31 KXS94943.1 - 1.6e-05 25.0 1.2 0.55 10.5 0.0 4.1 4 0 0 4 4 3 2 Myb-like DNA-binding domain HTH_40 PF14493.6 KXS94943.1 - 2.1e-05 24.9 0.0 0.76 10.3 0.0 3.9 4 0 0 4 4 4 2 Helix-turn-helix domain HTH_20 PF12840.7 KXS94943.1 - 9e-05 22.5 0.4 5 7.3 0.0 4.9 5 0 0 5 5 5 1 Helix-turn-helix domain DUF742 PF05331.11 KXS94943.1 - 0.00081 19.2 0.0 0.48 10.2 0.0 3.0 2 1 1 3 3 3 1 Protein of unknown function (DUF742) Myb_DNA-bind_6 PF13921.6 KXS94943.1 - 0.00085 19.5 1.8 0.42 10.9 0.0 3.6 4 0 0 4 4 4 1 Myb-like DNA-binding domain HTH_32 PF13565.6 KXS94943.1 - 0.0014 19.2 0.6 0.0014 19.2 0.6 4.8 2 1 4 6 6 6 1 Homeodomain-like domain MarR_2 PF12802.7 KXS94943.1 - 0.0015 18.4 1.4 1.9 8.4 0.0 3.7 4 0 0 4 4 4 1 MarR family MerR_1 PF13411.6 KXS94943.1 - 0.017 15.2 0.4 8.9 6.5 0.0 4.4 5 1 0 5 5 5 0 MerR HTH family regulatory protein HNH_repeat PF18780.1 KXS94943.1 - 0.018 14.8 0.1 0.063 13.1 0.1 2.0 1 0 0 1 1 1 0 Homing endonuclease repeat Rrf2 PF02082.20 KXS94943.1 - 0.024 15.0 0.1 0.6 10.5 0.0 2.7 3 0 0 3 3 3 0 Transcriptional regulator CENP-B_N PF04218.13 KXS94943.1 - 0.027 14.1 0.0 2.6 7.7 0.0 3.3 3 0 0 3 3 3 0 CENP-B N-terminal DNA-binding domain RPA_C PF08784.11 KXS94943.1 - 0.053 14.2 0.0 3 8.5 0.0 2.6 2 0 0 2 2 2 0 Replication protein A C terminal DUF2089 PF09862.9 KXS94943.1 - 0.15 12.1 0.0 1.6 8.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2089) Sugar_tr PF00083.24 KXS94944.1 - 2.8e-91 306.7 24.7 3.4e-91 306.4 24.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS94944.1 - 9.6e-18 64.2 25.0 9.6e-18 64.2 25.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXS94944.1 - 3.2e-06 26.0 18.5 0.0038 15.8 6.2 2.5 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_4 PF06779.14 KXS94944.1 - 2.3e-05 23.8 4.4 2.3e-05 23.8 4.4 1.8 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 KXS94944.1 - 0.6 8.9 12.1 0.04 12.8 6.1 1.8 2 0 0 2 2 2 0 MFS_1 like family PFK PF00365.20 KXS94945.1 - 9.1e-190 628.9 0.1 5.4e-106 354.1 0.1 2.1 2 0 0 2 2 2 2 Phosphofructokinase Na_Ca_ex PF01699.24 KXS94946.1 - 4.1e-21 75.5 33.2 6.8e-14 52.1 16.8 3.9 4 0 0 4 4 4 2 Sodium/calcium exchanger protein YccF PF03733.13 KXS94946.1 - 9.8e-16 58.2 7.8 9.8e-16 58.2 7.8 4.5 5 0 0 5 5 5 1 Inner membrane component domain PHO4 PF01384.20 KXS94946.1 - 0.16 11.0 4.4 0.91 8.5 4.4 2.2 1 1 0 1 1 1 0 Phosphate transporter family CAF1A PF12253.8 KXS94947.1 - 0.02 15.0 0.0 0.032 14.4 0.0 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A Alpha-amylase PF00128.24 KXS94948.1 - 5.7e-109 364.7 0.0 8.2e-109 364.2 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 KXS94948.1 - 0.0012 18.9 0.0 0.008 16.3 0.0 2.2 2 0 0 2 2 2 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 KXS94948.1 - 0.016 14.3 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Alpha-amylase_C PF02806.18 KXS94948.1 - 0.13 12.7 0.0 0.6 10.6 0.0 2.1 2 0 0 2 2 2 0 Alpha amylase, C-terminal all-beta domain CorA PF01544.18 KXS94952.1 - 5.3e-09 35.8 1.8 1.1e-08 34.8 1.8 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF350 PF03994.14 KXS94952.1 - 0.13 12.4 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF350) Pou PF00157.17 KXS94952.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Pou domain - N-terminal to homeobox domain CorA PF01544.18 KXS94953.1 - 5.3e-09 35.8 1.8 1.1e-08 34.8 1.8 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF350 PF03994.14 KXS94953.1 - 0.13 12.4 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF350) Pou PF00157.17 KXS94953.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Pou domain - N-terminal to homeobox domain Cellulase PF00150.18 KXS94958.1 - 6.6e-17 61.9 1.5 6.6e-17 61.9 1.5 2.1 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Cellulase PF00150.18 KXS94959.1 - 6.6e-17 61.9 1.5 6.6e-17 61.9 1.5 2.1 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) GATA PF00320.27 KXS94960.1 - 7.7e-16 57.4 4.9 1.5e-15 56.4 4.9 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 KXS94960.1 - 3.3e-14 52.9 0.0 6.1e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 KXS94960.1 - 4.5e-09 36.3 0.0 9.2e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 KXS94960.1 - 1.1e-06 28.8 0.0 2.4e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 KXS94960.1 - 1.9e-06 28.1 0.0 6.5e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 PAS domain PAS_11 PF14598.6 KXS94960.1 - 3.2e-05 24.0 0.0 6.6e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 PAS domain Zn-ribbon_8 PF09723.10 KXS94960.1 - 0.013 15.6 0.2 0.026 14.7 0.2 1.5 1 0 0 1 1 1 0 Zinc ribbon domain DUF4428 PF14471.6 KXS94960.1 - 1.7 8.6 5.5 0.46 10.4 1.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) Methyltransf_23 PF13489.6 KXS94962.1 - 1.1e-15 57.9 0.0 1.6e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS94962.1 - 9e-09 35.9 0.0 2.7e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS94962.1 - 1.5e-08 35.1 0.0 3.4e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS94962.1 - 2.8e-06 28.0 0.0 6.1e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS94962.1 - 0.00017 21.4 0.0 0.0011 18.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KXS94962.1 - 0.0034 16.9 0.0 0.0059 16.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_2 PF00891.18 KXS94962.1 - 0.033 13.5 0.0 0.055 12.8 0.0 1.5 1 1 0 1 1 1 0 O-methyltransferase domain Ubie_methyltran PF01209.18 KXS94962.1 - 0.059 12.7 0.0 0.22 10.8 0.0 1.8 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Tim29 PF10171.9 KXS94962.1 - 0.12 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Translocase of the Inner Mitochondrial membrane 29 Methyltransf_9 PF08003.11 KXS94962.1 - 0.13 11.2 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) zf-U1 PF06220.12 KXS94963.1 - 7.7e-22 76.8 3.4 1e-21 76.4 3.4 1.2 1 0 0 1 1 1 1 U1 zinc finger FAD-oxidase_C PF02913.19 KXS94964.1 - 2e-61 207.8 0.0 2.9e-61 207.3 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KXS94964.1 - 1.9e-36 124.9 0.0 3.8e-36 123.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain zf-C2HC_2 PF13913.6 KXS94964.1 - 0.3 11.1 1.4 0.64 10.0 1.4 1.5 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Acyl-CoA_dh_1 PF00441.24 KXS94965.1 - 5.4e-32 111.1 1.0 8.7e-32 110.4 1.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 KXS94965.1 - 5.5e-21 74.5 0.1 1.3e-20 73.3 0.1 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 KXS94965.1 - 3.1e-16 59.3 0.3 7.2e-16 58.2 0.3 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KXS94965.1 - 1.2e-08 35.6 0.2 3.6e-08 34.0 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KXS94965.1 - 1e-05 25.8 0.0 2.7e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF692 PF05114.13 KXS94965.1 - 0.2 10.8 0.6 6.6 5.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF692) adh_short PF00106.25 KXS94966.1 - 5.7e-09 35.7 0.1 5.2e-05 22.8 0.0 2.0 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXS94966.1 - 2.1e-06 27.5 0.1 0.0026 17.4 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase RNA_binding PF01877.17 KXS94968.1 - 0.11 12.8 0.1 0.18 12.1 0.1 1.4 1 0 0 1 1 1 0 RNA binding Mrpl_C PF18502.1 KXS94969.1 - 0.024 14.9 0.1 0.037 14.3 0.1 1.3 1 0 0 1 1 1 0 54S ribosomal protein L8 C-terminal domain DNA_pol_phi PF04931.13 KXS94970.1 - 0.22 9.6 11.2 0.47 8.5 11.2 1.5 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 KXS94970.1 - 0.27 10.6 8.7 0.58 9.5 8.7 1.5 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KXS94970.1 - 0.32 9.2 12.1 0.66 8.1 12.1 1.4 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KXS94970.1 - 0.94 7.7 7.0 1.7 6.9 7.0 1.4 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 KXS94970.1 - 4.3 6.6 14.0 0.18 11.1 7.9 1.8 2 0 0 2 2 2 0 BUD22 Brr6_like_C_C PF10104.9 KXS94971.1 - 0.012 15.3 0.7 0.018 14.8 0.7 1.2 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain Axin_b-cat_bind PF08833.10 KXS94972.1 - 0.039 14.1 3.3 1e+02 3.1 0.0 5.6 5 0 0 5 5 5 0 Axin beta-catenin binding domain DUF5556 PF17711.1 KXS94972.1 - 0.77 9.7 2.8 0.69 9.8 0.1 2.2 2 1 0 2 2 2 0 Family of unknown function (DUF5556) Cpta_toxin PF07254.12 KXS94972.1 - 3.4 7.7 7.5 33 4.5 0.1 4.2 1 1 5 6 6 6 0 Membrane-bound toxin component of toxin-antitoxin system p450 PF00067.22 KXS94973.1 - 6.1e-66 223.1 0.0 7.2e-66 222.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 acVLRF1 PF18859.1 KXS94973.1 - 0.13 12.6 0.1 0.24 11.7 0.1 1.4 1 0 0 1 1 1 0 Actinobacteria/chloroflexi VLRF1 release factor Mei5 PF10376.9 KXS94974.1 - 1 9.1 11.8 0.15 11.9 7.7 1.6 2 0 0 2 2 2 0 Double-strand recombination repair protein ADH_zinc_N PF00107.26 KXS94976.1 - 1.8e-24 86.2 0.0 3.4e-24 85.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXS94976.1 - 2.1e-20 72.7 1.3 3.3e-20 72.0 1.3 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KXS94976.1 - 1.6e-06 29.2 0.0 3.8e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 KXS94976.1 - 0.0018 18.6 0.1 0.0029 17.8 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_2 PF03446.15 KXS94976.1 - 0.0035 17.5 0.0 0.0057 16.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Methyltransf_25 PF13649.6 KXS94976.1 - 0.0065 17.2 0.1 0.015 16.0 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain 3HCDH_N PF02737.18 KXS94976.1 - 0.015 15.2 0.2 0.026 14.4 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KXS94976.1 - 0.017 14.5 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_12 PF08242.12 KXS94976.1 - 0.038 14.7 0.1 0.22 12.3 0.1 2.1 1 1 1 2 2 2 0 Methyltransferase domain ApbA PF02558.16 KXS94976.1 - 0.047 13.3 0.1 0.077 12.6 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TPMT PF05724.11 KXS94976.1 - 0.059 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_31 PF13847.6 KXS94976.1 - 0.086 12.6 0.3 0.31 10.8 0.2 1.9 1 1 0 1 1 1 0 Methyltransferase domain ThiF PF00899.21 KXS94976.1 - 0.12 11.7 0.1 0.23 10.8 0.1 1.4 1 0 0 1 1 1 0 ThiF family Methyltransf_11 PF08241.12 KXS94976.1 - 0.14 12.8 0.0 0.44 11.2 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain ABC_membrane PF00664.23 KXS94977.1 - 3.6e-92 308.9 26.6 5e-49 167.4 9.3 3.1 3 1 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXS94977.1 - 7e-68 227.4 0.0 1.4e-34 119.5 0.0 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KXS94977.1 - 2.4e-12 46.8 2.8 0.00087 18.8 0.0 4.4 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KXS94977.1 - 1.2e-07 31.4 3.2 0.0031 17.2 0.1 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KXS94977.1 - 1.7e-07 31.6 0.3 0.015 15.6 0.0 3.4 3 1 0 3 3 2 2 AAA domain ABC_ATPase PF09818.9 KXS94977.1 - 3.1e-07 29.6 3.0 0.011 14.6 0.1 3.2 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 KXS94977.1 - 1.1e-06 29.2 3.3 0.011 16.2 0.3 3.1 2 2 0 2 2 2 2 AAA ATPase domain APS_kinase PF01583.20 KXS94977.1 - 2.3e-06 27.6 0.5 0.04 13.8 0.1 4.0 4 0 0 4 4 4 1 Adenylylsulphate kinase AAA_28 PF13521.6 KXS94977.1 - 1.7e-05 25.2 0.8 0.13 12.5 0.4 3.0 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KXS94977.1 - 2.3e-05 25.0 0.0 0.056 14.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KXS94977.1 - 0.00011 21.9 0.1 0.12 12.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KXS94977.1 - 0.00013 21.9 3.3 0.34 10.7 0.1 3.4 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KXS94977.1 - 0.00015 21.7 0.1 0.6 10.0 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase DUF87 PF01935.17 KXS94977.1 - 0.00015 21.9 0.9 0.45 10.6 0.3 2.6 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_30 PF13604.6 KXS94977.1 - 0.00048 19.9 2.0 0.89 9.2 0.1 3.7 3 1 0 3 3 3 2 AAA domain PRK PF00485.18 KXS94977.1 - 0.001 18.8 0.1 0.96 9.1 0.1 2.6 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 KXS94977.1 - 0.0012 18.2 0.1 0.53 9.5 0.0 2.9 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.6 KXS94977.1 - 0.0017 18.5 0.0 2.7 8.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KXS94977.1 - 0.0028 17.4 0.1 2 8.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain G-alpha PF00503.20 KXS94977.1 - 0.0049 16.1 0.0 0.88 8.7 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit SbcCD_C PF13558.6 KXS94977.1 - 0.0078 16.4 3.3 4.1 7.7 0.2 3.9 3 2 0 3 3 2 1 Putative exonuclease SbcCD, C subunit KAP_NTPase PF07693.14 KXS94977.1 - 0.009 15.3 0.0 0.35 10.1 0.0 2.6 2 0 0 2 2 2 1 KAP family P-loop domain DUF3094 PF11293.8 KXS94977.1 - 0.0091 15.7 0.1 0.032 14.0 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3094) Fzo_mitofusin PF04799.13 KXS94977.1 - 0.01 15.4 0.4 0.029 13.9 0.4 1.7 1 0 0 1 1 1 0 fzo-like conserved region MMR_HSR1 PF01926.23 KXS94977.1 - 0.012 15.6 0.1 6.7 6.8 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 KXS94977.1 - 0.024 14.0 0.5 7.2 5.9 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.6 KXS94977.1 - 0.029 14.9 0.7 6.5 7.2 0.1 2.7 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 KXS94977.1 - 0.044 13.4 1.3 1.7 8.3 0.0 3.0 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain NACHT PF05729.12 KXS94977.1 - 0.051 13.5 1.0 2.7 7.9 0.1 3.1 4 0 0 4 4 2 0 NACHT domain T2SSE PF00437.20 KXS94977.1 - 0.054 12.6 0.2 7.3 5.6 0.1 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein Ploopntkinase3 PF18751.1 KXS94977.1 - 0.055 13.4 0.2 6 6.7 0.0 2.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_15 PF13175.6 KXS94977.1 - 0.12 12.1 1.7 0.75 9.4 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain VAD1-2 PF15310.6 KXS94977.1 - 0.13 12.1 0.1 0.25 11.2 0.1 1.3 1 0 0 1 1 1 0 Vitamin A-deficiency (VAD) rat model signalling AAA_5 PF07728.14 KXS94977.1 - 0.14 12.2 1.0 19 5.3 0.0 3.4 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KXS94977.1 - 0.15 11.5 0.1 15 5.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_17 PF13207.6 KXS94977.1 - 0.18 12.2 0.2 42 4.6 0.0 3.3 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 KXS94977.1 - 0.2 11.6 0.5 3.7 7.4 0.1 3.0 3 0 0 3 3 3 0 NTPase GP41 PF00517.17 KXS94977.1 - 1.4 8.8 5.8 5.9 6.7 0.5 3.5 3 0 0 3 3 3 0 Retroviral envelope protein GNAT_acetyltr_2 PF13718.6 KXS94978.1 - 3.1e-98 327.7 0.0 8.5e-98 326.3 0.0 1.8 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 KXS94978.1 - 1.5e-85 286.7 0.5 1.5e-85 286.7 0.5 2.4 2 1 1 3 3 3 1 Possible tRNA binding domain Helicase_RecD PF05127.14 KXS94978.1 - 2.6e-66 222.8 0.0 1.5e-65 220.3 0.0 2.4 3 0 0 3 3 3 1 Helicase DUF1726 PF08351.11 KXS94978.1 - 2.5e-33 113.9 0.4 6.1e-33 112.6 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 KXS94978.1 - 0.00034 20.4 0.1 0.025 14.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KXS94978.1 - 0.014 15.7 0.0 0.36 11.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KXS94978.1 - 0.028 14.7 0.0 0.13 12.5 0.0 2.2 1 0 0 1 1 1 0 AAA domain Acetyltransf_1 PF00583.25 KXS94978.1 - 0.11 12.7 0.0 0.65 10.3 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family DUF2263 PF10021.9 KXS94979.1 - 1.2e-17 64.7 0.0 4.2e-17 62.9 0.0 1.9 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) ADK_lid PF05191.14 KXS94980.1 - 0.038 14.0 0.9 0.12 12.4 0.9 1.8 1 0 0 1 1 1 0 Adenylate kinase, active site lid LZ_Tnp_IS66 PF13007.7 KXS94981.1 - 2.3 9.1 6.2 12 6.7 0.7 2.9 2 1 0 2 2 2 0 Transposase C of IS166 homeodomain Glyco_transf_90 PF05686.12 KXS94982.1 - 1.9e-14 53.4 0.3 7.7e-09 34.9 0.1 3.7 2 1 0 2 2 2 2 Glycosyl transferase family 90 DUF4267 PF14087.6 KXS94982.1 - 0.25 11.4 3.2 0.25 11.4 0.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4267) DUF2070 PF09843.9 KXS94982.1 - 5.7 5.1 10.5 8.8 4.5 10.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF3294 PF07957.11 KXS94983.1 - 0.1 12.4 0.4 2.2 8.0 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3294) Rhodanese PF00581.20 KXS94984.1 - 5.4e-07 30.1 0.0 1e-06 29.2 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain ketoacyl-synt PF00109.26 KXS94985.1 - 1.6e-69 234.3 0.0 4e-69 233.0 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.28 KXS94985.1 - 1.2e-65 221.8 0.0 2.2e-65 220.9 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KXS94985.1 - 2.3e-57 194.7 0.0 3.9e-57 193.9 0.0 1.2 1 0 0 1 1 1 1 Condensation domain KR PF08659.10 KXS94985.1 - 4.7e-51 173.3 0.1 1.1e-50 172.1 0.1 1.7 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 KXS94985.1 - 1.6e-49 168.8 0.0 2.6e-49 168.1 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KXS94985.1 - 4.8e-47 161.0 0.0 9.2e-47 160.1 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXS94985.1 - 8.8e-27 93.5 0.0 2.6e-26 92.0 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KXS94985.1 - 2.2e-18 66.8 0.0 6.3e-18 65.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KXS94985.1 - 1.2e-17 64.0 1.2 1.4e-09 38.1 0.2 3.2 2 0 0 2 2 2 2 Phosphopantetheine attachment site NAD_binding_4 PF07993.12 KXS94985.1 - 1.5e-17 63.6 0.0 3.7e-16 59.1 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 KXS94985.1 - 4.1e-13 49.2 0.0 7.4e-12 45.1 0.0 2.5 2 0 0 2 2 2 1 short chain dehydrogenase KAsynt_C_assoc PF16197.5 KXS94985.1 - 9.7e-13 48.6 0.0 5.2e-12 46.2 0.0 2.3 2 0 0 2 2 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 KXS94985.1 - 8.3e-12 45.7 0.1 2.7e-11 44.0 0.1 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS94985.1 - 2.4e-11 44.1 0.1 6.6e-11 42.7 0.1 1.9 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 KXS94985.1 - 2.6e-11 43.4 0.0 1.5e-08 34.4 0.0 2.7 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Methyltransf_23 PF13489.6 KXS94985.1 - 1.6e-09 37.8 0.0 3.2e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 KXS94985.1 - 1.2e-08 34.8 0.0 3e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ubie_methyltran PF01209.18 KXS94985.1 - 1e-06 28.3 0.0 2.1e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KXS94985.1 - 2.3e-06 27.5 0.0 5.5e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 KXS94985.1 - 0.0019 17.6 0.0 0.0048 16.3 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain AMP-binding_C PF13193.6 KXS94985.1 - 0.0048 17.8 0.0 0.021 15.8 0.0 2.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Methyltransf_8 PF05148.15 KXS94985.1 - 0.024 14.5 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase 3Beta_HSD PF01073.19 KXS94985.1 - 0.056 12.4 0.0 5.3 6.0 0.0 2.4 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_24 PF13578.6 KXS94985.1 - 0.12 13.4 1.3 0.72 10.9 0.1 3.1 3 0 0 3 3 1 0 Methyltransferase domain Aminotran_4 PF01063.19 KXS94986.1 - 3.9e-27 95.5 0.0 5.7e-27 95.0 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV ADH_N PF08240.12 KXS94987.1 - 6.2e-05 22.8 0.0 0.00015 21.6 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXS94987.1 - 0.00011 22.2 0.0 0.00024 21.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Zn_clus PF00172.18 KXS94988.1 - 2.4e-06 27.5 8.0 2.4e-06 27.5 8.0 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXS94988.1 - 0.00027 20.1 0.4 0.00045 19.3 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Serglycin PF04360.12 KXS94988.1 - 0.29 11.1 5.7 0.52 10.2 5.7 1.3 1 0 0 1 1 1 0 Serglycin TRP PF06011.12 KXS94989.1 - 3.5e-38 131.4 22.2 7.5e-37 127.1 22.2 2.1 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KXS94989.1 - 4.7e-22 78.8 0.1 7.5e-22 78.2 0.1 1.3 1 0 0 1 1 1 1 ML-like domain DUF2627 PF11118.8 KXS94989.1 - 0.09 13.4 1.6 0.25 12.0 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) YCII PF03795.14 KXS94990.1 - 4.2e-09 36.7 0.0 5.4e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain FAD_binding_3 PF01494.19 KXS94991.1 - 1e-19 71.0 2.1 1e-16 61.2 0.1 2.8 2 1 0 2 2 2 2 FAD binding domain Amino_oxidase PF01593.24 KXS94991.1 - 0.00027 20.4 0.2 0.0069 15.7 0.0 2.5 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase DAO PF01266.24 KXS94991.1 - 0.00065 19.4 4.0 0.0017 18.0 2.2 2.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXS94991.1 - 0.0016 18.6 0.4 0.0046 17.2 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXS94991.1 - 0.0069 15.6 0.1 0.1 11.8 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXS94991.1 - 0.047 13.7 0.0 5.7 6.9 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding SE PF08491.10 KXS94991.1 - 0.055 12.5 0.0 0.35 9.9 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox PF00070.27 KXS94991.1 - 0.083 13.5 0.5 0.23 12.0 0.5 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DIOX_N PF14226.6 KXS94993.1 - 1.2e-29 103.5 0.0 1.5e-29 103.2 0.0 1.1 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal HTH_51 PF18558.1 KXS94994.1 - 8.2e-26 89.7 0.0 1.9e-25 88.5 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain NAD_binding_4 PF07993.12 KXS94994.1 - 2.5e-19 69.5 0.0 4.2e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 KXS94994.1 - 5.5e-13 49.1 0.7 1.2e-12 47.9 0.7 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_12 PF08242.12 KXS94994.1 - 6.4e-13 49.3 0.0 1.8e-12 47.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXS94994.1 - 4.2e-10 39.7 0.0 3.2e-09 36.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain PS-DH PF14765.6 KXS94994.1 - 4.8e-10 39.2 0.0 9.8e-10 38.1 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_25 PF13649.6 KXS94994.1 - 7.6e-08 33.0 0.0 2.3e-07 31.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS94994.1 - 2.3e-06 27.5 0.0 4.2e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 KXS94994.1 - 1.3e-05 24.8 0.0 3.2e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_11 PF08241.12 KXS94994.1 - 2.2e-05 25.0 0.0 7.8e-05 23.2 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain NodS PF05401.11 KXS94994.1 - 0.0045 16.6 0.0 0.0082 15.8 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_16 PF10294.9 KXS94994.1 - 0.0078 16.0 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase KR PF08659.10 KXS94994.1 - 0.12 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 KR domain Sde2_N_Ubi PF13019.6 KXS94994.1 - 0.16 11.8 0.0 0.43 10.4 0.0 1.6 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain Polysacc_synt_2 PF02719.15 KXS94994.1 - 0.2 10.8 0.0 0.32 10.1 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PMSR PF01625.21 KXS94995.1 - 4.3e-63 212.1 1.5 5.1e-63 211.8 1.5 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase adh_short PF00106.25 KXS94996.1 - 5.4e-30 104.3 0.0 1.4e-20 73.6 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXS94996.1 - 2.5e-20 73.0 0.0 1.9e-11 44.0 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS94996.1 - 5.6e-06 26.4 0.0 9.5e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS94996.1 - 0.032 13.7 0.0 0.072 12.5 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family FSH1 PF03959.13 KXS94997.1 - 1.4e-29 103.3 0.0 1.9e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 KXS94997.1 - 0.0072 16.2 0.0 0.072 12.9 0.0 2.0 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase adh_short PF00106.25 KXS94998.1 - 5.6e-33 114.0 0.0 8e-33 113.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS94998.1 - 2e-24 86.5 0.0 2.7e-24 86.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS94998.1 - 1.2e-10 41.6 0.0 1.7e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXS94998.1 - 0.16 11.1 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein FAD_binding_3 PF01494.19 KXS94999.1 - 6.6e-18 65.1 0.1 2e-17 63.5 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXS94999.1 - 0.00018 20.8 0.1 0.0054 16.0 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXS94999.1 - 0.00098 19.1 0.1 0.37 10.8 0.1 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KXS94999.1 - 0.0012 19.1 1.7 0.0028 17.9 0.6 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXS94999.1 - 0.0016 18.9 0.1 0.0042 17.6 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXS94999.1 - 0.0022 17.7 3.0 0.0095 15.6 0.9 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KXS94999.1 - 0.0055 15.8 0.6 1.5 7.8 0.2 2.7 3 0 0 3 3 3 2 Lycopene cyclase protein Trp_halogenase PF04820.14 KXS94999.1 - 0.017 14.0 0.3 0.48 9.2 0.3 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Amino_oxidase PF01593.24 KXS94999.1 - 0.022 14.1 0.0 0.039 13.3 0.0 1.5 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase 3HCDH_N PF02737.18 KXS94999.1 - 0.025 14.5 0.3 0.057 13.3 0.2 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 KXS94999.1 - 0.039 13.6 0.1 0.066 12.9 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 KXS94999.1 - 0.14 10.9 0.3 0.21 10.3 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein YCII PF03795.14 KXS95000.1 - 1.8e-05 25.1 0.0 2.6e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 YCII-related domain MFS_1 PF07690.16 KXS95001.1 - 1.4e-17 63.6 35.0 1.4e-17 63.6 35.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 KXS95002.1 - 1.3e-13 50.6 0.6 2.2e-13 49.9 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ferric_reduct PF01794.19 KXS95004.1 - 2.5e-18 66.4 12.5 2.5e-18 66.4 12.5 2.8 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KXS95004.1 - 2.2e-16 60.3 0.0 3.8e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KXS95004.1 - 3e-14 53.0 0.0 6.1e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Zn_clus PF00172.18 KXS95005.1 - 6.1e-05 23.1 8.4 0.00011 22.2 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GCP_C_terminal PF04130.13 KXS95006.1 - 2.3e-54 185.0 3.6 2e-53 181.9 1.5 2.5 2 1 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KXS95006.1 - 1.1e-12 48.2 0.1 1.1e-12 48.2 0.1 2.5 2 1 1 3 3 3 1 Gamma tubulin complex component N-terminal RAP1 PF07218.11 KXS95007.1 - 9.7 4.3 9.0 11 4.1 9.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Peptidase_S10 PF00450.22 KXS95008.1 - 7.7e-88 295.7 2.9 9.1e-88 295.5 2.9 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase N-SET PF11764.8 KXS95019.1 - 4.8e-55 186.3 0.1 4.8e-55 186.3 0.1 3.6 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.8 KXS95019.1 - 1.1e-26 92.2 0.0 2.7e-26 91.0 0.0 1.7 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated SET PF00856.28 KXS95019.1 - 9.8e-20 71.6 0.1 9.8e-20 71.6 0.1 3.6 3 2 0 3 3 3 1 SET domain RRM_1 PF00076.22 KXS95019.1 - 0.00019 21.2 0.0 0.0006 19.6 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LAM_C PF12544.8 KXS95019.1 - 0.17 12.1 1.5 26 5.0 0.5 3.1 2 0 0 2 2 2 0 Lysine-2,3-aminomutase Cupin_2 PF07883.11 KXS95020.1 - 9.9e-11 41.2 0.5 0.00012 21.8 0.3 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KXS95020.1 - 0.00016 21.3 0.0 0.0057 16.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF861) Cupin_6 PF12852.7 KXS95020.1 - 0.00029 20.6 0.0 0.014 15.1 0.0 2.3 2 0 0 2 2 2 1 Cupin EutQ PF06249.12 KXS95020.1 - 0.0019 18.0 0.0 0.0031 17.3 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_1 PF00190.22 KXS95020.1 - 0.056 13.0 0.1 1.9 8.1 0.0 2.2 2 0 0 2 2 2 0 Cupin Poxvirus_B22R_N PF13169.6 KXS95021.1 - 0.16 12.5 0.0 0.2 12.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus B22R protein N-terminal PD40 PF07676.12 KXS95022.1 - 8.3e-48 159.4 30.0 2e-07 30.8 1.1 11.3 10 1 1 11 11 11 9 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 KXS95022.1 - 5.4e-11 41.8 5.9 0.0096 14.7 0.6 7.3 4 2 1 6 6 6 3 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF3748 PF12566.8 KXS95022.1 - 3.7e-06 26.9 2.0 6.5 6.7 0.1 5.7 6 0 0 6 6 6 2 Protein of unknown function (DUF3748) DUF5050 PF16472.5 KXS95022.1 - 2.7e-05 23.6 0.0 0.31 10.2 0.0 3.9 4 1 0 4 4 4 2 Domain of unknown function (DUF5050) Gmad1 PF10647.9 KXS95022.1 - 0.0071 16.1 0.4 17 5.0 0.2 4.5 3 2 1 5 5 5 1 Lipoprotein LpqB beta-propeller domain Robl_LC7 PF03259.17 KXS95022.1 - 0.12 12.2 0.0 0.93 9.3 0.0 2.2 2 0 0 2 2 2 0 Roadblock/LC7 domain WD40 PF00400.32 KXS95022.1 - 0.44 11.5 13.1 33 5.6 1.1 7.0 8 1 1 9 9 9 0 WD domain, G-beta repeat PD40 PF07676.12 KXS95023.1 - 8.3e-48 159.4 30.0 2e-07 30.8 1.1 11.3 10 1 1 11 11 11 9 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 KXS95023.1 - 5.4e-11 41.8 5.9 0.0096 14.7 0.6 7.3 4 2 1 6 6 6 3 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF3748 PF12566.8 KXS95023.1 - 3.7e-06 26.9 2.0 6.5 6.7 0.1 5.7 6 0 0 6 6 6 2 Protein of unknown function (DUF3748) DUF5050 PF16472.5 KXS95023.1 - 2.7e-05 23.6 0.0 0.31 10.2 0.0 3.9 4 1 0 4 4 4 2 Domain of unknown function (DUF5050) Gmad1 PF10647.9 KXS95023.1 - 0.0071 16.1 0.4 17 5.0 0.2 4.5 3 2 1 5 5 5 1 Lipoprotein LpqB beta-propeller domain Robl_LC7 PF03259.17 KXS95023.1 - 0.12 12.2 0.0 0.93 9.3 0.0 2.2 2 0 0 2 2 2 0 Roadblock/LC7 domain WD40 PF00400.32 KXS95023.1 - 0.44 11.5 13.1 33 5.6 1.1 7.0 8 1 1 9 9 9 0 WD domain, G-beta repeat PD40 PF07676.12 KXS95024.1 - 8.3e-48 159.4 30.0 2e-07 30.8 1.1 11.3 10 1 1 11 11 11 9 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 KXS95024.1 - 5.4e-11 41.8 5.9 0.0096 14.7 0.6 7.3 4 2 1 6 6 6 3 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF3748 PF12566.8 KXS95024.1 - 3.7e-06 26.9 2.0 6.5 6.7 0.1 5.7 6 0 0 6 6 6 2 Protein of unknown function (DUF3748) DUF5050 PF16472.5 KXS95024.1 - 2.7e-05 23.6 0.0 0.31 10.2 0.0 3.9 4 1 0 4 4 4 2 Domain of unknown function (DUF5050) Gmad1 PF10647.9 KXS95024.1 - 0.0071 16.1 0.4 17 5.0 0.2 4.5 3 2 1 5 5 5 1 Lipoprotein LpqB beta-propeller domain Robl_LC7 PF03259.17 KXS95024.1 - 0.12 12.2 0.0 0.93 9.3 0.0 2.2 2 0 0 2 2 2 0 Roadblock/LC7 domain WD40 PF00400.32 KXS95024.1 - 0.44 11.5 13.1 33 5.6 1.1 7.0 8 1 1 9 9 9 0 WD domain, G-beta repeat bZIP_1 PF00170.21 KXS95025.1 - 3.3e-05 23.9 3.6 8.8e-05 22.5 3.6 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXS95025.1 - 0.037 14.1 3.8 0.097 12.8 3.8 1.7 1 0 0 1 1 1 0 Basic region leucine zipper DUF2894 PF11445.8 KXS95025.1 - 0.13 12.7 3.0 0.13 12.7 1.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) FMO-like PF00743.19 KXS95026.1 - 1.5e-44 152.4 0.0 1e-25 90.2 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXS95026.1 - 2.5e-16 59.8 0.3 1.4e-10 40.9 0.3 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXS95026.1 - 3.5e-11 42.9 0.0 1.1e-10 41.3 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXS95026.1 - 4.6e-09 36.5 1.7 7.6e-08 32.5 0.9 3.2 3 1 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 KXS95026.1 - 2.3e-08 34.0 0.1 0.0013 18.4 0.1 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.17 KXS95026.1 - 3.5e-08 33.0 0.0 2.7e-05 23.5 0.0 2.2 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.6 KXS95026.1 - 1.4e-07 31.6 0.0 3.6e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KXS95026.1 - 1.9e-07 30.6 1.4 7.5e-05 22.0 0.2 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 KXS95026.1 - 0.00011 21.0 0.1 0.036 12.8 0.1 2.3 2 0 0 2 2 2 2 HI0933-like protein Amino_oxidase PF01593.24 KXS95026.1 - 0.0007 19.0 0.0 0.041 13.2 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase MCRA PF06100.11 KXS95026.1 - 0.014 14.2 0.1 0.028 13.2 0.0 1.5 2 0 0 2 2 2 0 MCRA family Pyr_redox PF00070.27 KXS95026.1 - 0.033 14.8 1.0 0.12 13.0 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXS95026.1 - 0.038 13.2 0.0 0.075 12.3 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Adeno_VII PF03228.14 KXS95026.1 - 0.051 14.2 0.3 0.18 12.5 0.2 1.8 2 0 0 2 2 2 0 Adenoviral core protein VII FAD_binding_2 PF00890.24 KXS95026.1 - 0.12 11.4 0.0 1.2 8.2 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Glu_dehyd_C PF16912.5 KXS95026.1 - 0.14 11.6 0.0 0.45 10.0 0.0 1.8 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus Pam16 PF03656.13 KXS95028.1 - 3.9e-34 117.4 0.1 4.7e-34 117.1 0.1 1.1 1 0 0 1 1 1 1 Pam16 HTH_17 PF12728.7 KXS95028.1 - 0.081 13.1 0.0 0.13 12.4 0.0 1.5 1 1 0 1 1 1 0 Helix-turn-helix domain Pam16 PF03656.13 KXS95029.1 - 8.5e-35 119.5 0.6 1.1e-34 119.2 0.6 1.1 1 0 0 1 1 1 1 Pam16 HTH_17 PF12728.7 KXS95029.1 - 0.063 13.5 0.0 0.13 12.5 0.0 1.7 1 1 0 1 1 1 0 Helix-turn-helix domain HsbA PF12296.8 KXS95030.1 - 3.6e-26 92.0 15.5 3.6e-26 92.0 15.5 1.9 2 0 0 2 2 2 1 Hydrophobic surface binding protein A Apolipoprotein PF01442.18 KXS95030.1 - 0.16 11.8 1.9 0.59 10.0 2.1 1.8 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain HTH_psq PF05225.16 KXS95030.1 - 0.19 11.5 1.9 0.51 10.1 0.1 2.4 2 0 0 2 2 2 0 helix-turn-helix, Psq domain Anti-adapt_IraP PF10796.9 KXS95030.1 - 0.21 12.1 0.9 0.51 10.9 0.3 1.9 2 0 0 2 2 2 0 Sigma-S stabilisation anti-adaptor protein HsbA PF12296.8 KXS95031.1 - 6.2e-26 91.2 15.5 6.2e-26 91.2 15.5 1.9 2 0 0 2 2 2 1 Hydrophobic surface binding protein A Alpha_GJ PF03229.13 KXS95032.1 - 0.19 12.3 20.2 0.25 11.9 20.2 1.0 1 0 0 1 1 1 0 Alphavirus glycoprotein J HsbA PF12296.8 KXS95033.1 - 2e-26 92.8 15.5 3.2e-26 92.1 15.5 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Anti-adapt_IraP PF10796.9 KXS95033.1 - 0.45 11.1 2.2 0.81 10.3 1.1 2.0 2 1 0 2 2 2 0 Sigma-S stabilisation anti-adaptor protein FMO-like PF00743.19 KXS95037.1 - 7.6e-16 57.6 0.0 5.6e-15 54.8 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KXS95037.1 - 3.6e-12 46.1 0.1 1.9e-10 40.4 0.1 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KXS95037.1 - 2.7e-11 43.3 0.0 8.4e-10 38.4 0.0 2.4 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXS95037.1 - 1.3e-10 41.0 0.0 8.7e-08 31.7 0.0 2.6 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXS95037.1 - 8.9e-07 29.1 0.2 5.4e-05 23.3 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KXS95037.1 - 0.008 16.2 0.6 34 4.4 0.0 4.3 4 1 1 5 5 5 0 FAD-NAD(P)-binding HTH_38 PF13936.6 KXS95037.1 - 0.025 14.3 0.2 4.4 7.1 0.0 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain Pyr_redox PF00070.27 KXS95037.1 - 0.045 14.3 1.3 9.1 6.9 0.0 3.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase ATP-synt_S1 PF05827.12 KXS95038.1 - 0.00012 21.9 1.6 0.00032 20.6 1.6 1.6 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) FAD_binding_4 PF01565.23 KXS95039.1 - 8e-24 84.0 3.4 8e-24 84.0 3.4 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KXS95039.1 - 4.8e-12 45.8 0.5 9.2e-12 44.9 0.5 1.5 1 0 0 1 1 1 1 Berberine and berberine like Tropomyosin_1 PF12718.7 KXS95040.1 - 1.1e-51 174.7 33.9 1.3e-51 174.5 33.9 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 KXS95040.1 - 5.7e-07 29.1 31.6 7e-05 22.3 10.7 2.7 1 1 2 3 3 3 3 Tropomyosin GAS PF13851.6 KXS95040.1 - 0.004 16.5 29.3 0.038 13.3 22.2 2.3 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 KXS95040.1 - 0.018 15.1 15.6 0.18 11.9 2.3 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 KXS95040.1 - 0.028 14.5 3.3 0.028 14.5 3.3 2.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4200 PF13863.6 KXS95040.1 - 0.054 13.9 29.9 0.24 11.8 10.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) ADIP PF11559.8 KXS95040.1 - 0.06 13.4 29.2 0.15 12.2 9.5 2.7 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding ATG16 PF08614.11 KXS95040.1 - 0.067 13.4 31.1 1.2 9.4 12.3 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) bZIP_1 PF00170.21 KXS95040.1 - 0.077 13.1 27.6 0.29 11.3 6.5 4.8 3 1 2 5 5 5 0 bZIP transcription factor SOGA PF11365.8 KXS95040.1 - 0.079 14.1 20.3 5.4 8.2 0.7 3.3 2 1 1 3 3 3 0 Protein SOGA TMF_DNA_bd PF12329.8 KXS95040.1 - 0.097 12.7 34.3 0.042 13.9 15.0 3.2 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding TMF_TATA_bd PF12325.8 KXS95040.1 - 0.1 12.8 24.0 0.32 11.2 16.1 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding KLRAQ PF10205.9 KXS95040.1 - 0.11 12.7 21.2 0.078 13.2 8.6 2.7 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein Uso1_p115_C PF04871.13 KXS95040.1 - 0.12 12.8 37.2 0.13 12.6 14.8 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region HOOK PF05622.12 KXS95040.1 - 0.13 10.4 26.2 0.17 10.0 26.2 1.2 1 0 0 1 1 1 0 HOOK protein Seryl_tRNA_N PF02403.22 KXS95040.1 - 0.15 12.3 25.2 0.64 10.3 0.7 3.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Jnk-SapK_ap_N PF09744.9 KXS95040.1 - 0.16 12.2 30.4 0.14 12.4 18.9 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 HMMR_N PF15905.5 KXS95040.1 - 0.2 11.1 25.6 0.24 10.8 25.6 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal ERM PF00769.19 KXS95040.1 - 0.29 10.9 37.3 0.12 12.2 14.5 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family HMMR_C PF15908.5 KXS95040.1 - 0.34 11.2 18.2 0.32 11.2 2.9 2.9 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor C-terminal DUF812 PF05667.11 KXS95040.1 - 0.52 9.1 28.4 0.83 8.5 28.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Spc7 PF08317.11 KXS95040.1 - 0.59 9.0 32.3 0.83 8.5 13.9 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Taxilin PF09728.9 KXS95040.1 - 0.65 9.1 31.3 0.67 9.1 11.4 2.2 1 1 1 2 2 2 0 Myosin-like coiled-coil protein Laminin_II PF06009.12 KXS95040.1 - 0.73 9.8 18.2 0.13 12.3 4.5 2.2 1 1 1 2 2 2 0 Laminin Domain II Cortex-I_coil PF09304.10 KXS95040.1 - 0.74 10.1 23.3 3.1 8.1 5.3 3.0 1 1 2 3 3 3 0 Cortexillin I, coiled coil DUF724 PF05266.14 KXS95040.1 - 0.86 9.4 25.4 1 9.2 7.7 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF724) Fib_alpha PF08702.10 KXS95040.1 - 1 9.5 13.7 2 8.6 3.0 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Imm7 PF15585.6 KXS95040.1 - 1.2 9.4 6.9 1.3 9.3 0.7 2.1 2 0 0 2 2 2 0 Immunity protein 7 CENP-H PF05837.12 KXS95040.1 - 1.2 9.6 25.2 2.8 8.4 9.0 3.0 1 1 2 3 3 3 0 Centromere protein H (CENP-H) MAD PF05557.13 KXS95040.1 - 1.4 7.2 28.2 1.8 6.8 28.2 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein DUF4201 PF13870.6 KXS95040.1 - 1.6 8.4 24.7 3.4 7.4 9.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) BRE1 PF08647.11 KXS95040.1 - 1.8 8.7 32.5 0.65 10.1 18.3 2.5 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase HAUS-augmin3 PF14932.6 KXS95040.1 - 3 7.4 27.7 1.4 8.5 10.1 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Fez1 PF06818.15 KXS95040.1 - 3 8.3 26.3 17 5.8 26.6 1.8 1 1 0 1 1 1 0 Fez1 DUF3450 PF11932.8 KXS95040.1 - 3.6 6.8 28.0 3.5 6.9 10.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF3584 PF12128.8 KXS95040.1 - 3.9 4.9 27.6 5.2 4.5 27.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FlaC_arch PF05377.11 KXS95040.1 - 4.2 7.8 18.5 0.34 11.3 5.5 3.8 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) TPR_MLP1_2 PF07926.12 KXS95040.1 - 4.7 7.3 36.7 57 3.8 18.4 2.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein LRS4 PF10422.9 KXS95040.1 - 5 6.6 21.1 19 4.7 21.1 1.8 1 1 0 1 1 1 0 Monopolin complex subunit LRS4 DUF4407 PF14362.6 KXS95040.1 - 5.2 6.3 25.3 11 5.3 25.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Fmp27_WPPW PF10359.9 KXS95040.1 - 5.3 5.8 23.9 2.8 6.7 7.6 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain BST2 PF16716.5 KXS95040.1 - 5.3 7.7 24.5 0.16 12.6 4.3 3.2 1 1 1 2 2 1 0 Bone marrow stromal antigen 2 SlyX PF04102.12 KXS95040.1 - 5.4 7.7 21.0 1.1 10.0 6.1 3.7 1 1 2 3 3 3 0 SlyX APG6_N PF17675.1 KXS95040.1 - 5.9 7.4 39.1 5.8 7.4 13.8 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region Lebercilin PF15619.6 KXS95040.1 - 6.2 6.4 31.0 86 2.7 20.4 2.4 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease YabA PF06156.13 KXS95040.1 - 7.8 7.2 20.9 72 4.1 6.4 2.7 1 1 1 2 2 2 0 Initiation control protein YabA UPF0242 PF06785.11 KXS95040.1 - 8.9 6.4 30.0 1.3 9.1 12.0 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus KASH_CCD PF14662.6 KXS95040.1 - 9.8 6.0 29.6 5.3 6.8 11.1 2.4 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF2371 PF10177.9 KXS95043.1 - 0.2 11.8 0.6 0.35 11.0 0.6 1.4 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) Nop25 PF09805.9 KXS95044.1 - 2e-31 109.3 16.6 2e-31 109.3 16.6 2.8 1 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) GST_C PF00043.25 KXS95044.1 - 4.6 7.5 6.9 1.8 8.8 0.9 2.6 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain HET PF06985.11 KXS95048.1 - 8.1e-31 107.3 0.0 1.8e-30 106.2 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 KXS95049.1 - 7.9e-31 107.4 0.0 1.8e-30 106.2 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SEN1_N PF12726.7 KXS95050.1 - 9e-169 563.2 0.0 1.2e-168 562.8 0.0 1.2 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 KXS95050.1 - 5e-72 242.8 2.6 5e-72 242.8 2.6 2.8 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 KXS95050.1 - 1.4e-59 201.1 0.0 2.7e-59 200.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXS95050.1 - 4.4e-08 33.1 0.6 4.6e-05 23.2 0.3 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KXS95050.1 - 6.1e-08 33.1 0.1 2.1e-07 31.4 0.1 2.0 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 KXS95050.1 - 8e-06 25.6 5.7 2.2e-05 24.1 0.4 2.8 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 KXS95050.1 - 0.00085 19.1 0.0 1.5 8.5 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 KXS95050.1 - 0.055 13.7 0.0 0.45 10.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KXS95050.1 - 0.24 11.9 7.3 0.2 12.1 0.3 2.7 2 0 0 2 2 2 0 AAA domain SnoaL_2 PF12680.7 KXS95051.1 - 0.14 12.8 0.0 0.21 12.3 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain Orf78 PF06024.12 KXS95052.1 - 0.0076 16.5 0.0 0.026 14.8 0.0 1.9 1 0 0 1 1 1 1 Orf78 (ac78) RIFIN PF02009.16 KXS95052.1 - 0.14 12.0 0.3 0.41 10.5 0.0 1.8 2 0 0 2 2 2 0 Rifin EphA2_TM PF14575.6 KXS95052.1 - 0.2 12.6 0.4 0.55 11.1 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 KXS95052.1 - 0.33 10.9 1.7 0.49 10.3 0.0 2.2 2 0 0 2 2 2 0 TMEM154 protein family DUF4229 PF14012.6 KXS95052.1 - 3 8.0 7.3 0.092 12.9 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) DUF5102 PF17104.5 KXS95053.1 - 9.8e-06 25.8 14.8 0.0021 18.2 0.4 3.8 2 2 2 4 4 4 2 Domain of unknown function (DUF5102) HLH PF00010.26 KXS95054.1 - 0.16 12.0 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain FAD_binding_3 PF01494.19 KXS95055.1 - 5.9e-12 45.5 0.0 1.5e-11 44.2 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXS95055.1 - 0.00038 19.8 0.2 0.071 12.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXS95055.1 - 0.00047 20.3 0.0 0.0015 18.7 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXS95055.1 - 0.00071 19.3 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KXS95055.1 - 0.0056 15.6 0.3 0.1 11.4 0.1 2.4 3 0 0 3 3 3 1 Tryptophan halogenase Pyr_redox PF00070.27 KXS95055.1 - 0.027 15.0 0.6 2.3 8.9 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXS95055.1 - 0.044 13.8 0.2 1.7 8.6 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KXS95055.1 - 0.2 10.7 0.4 0.3 10.1 0.4 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 KXS95055.1 - 0.24 10.6 1.8 7.8 5.6 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MIP PF00230.20 KXS95056.1 - 1.6e-49 168.7 18.0 2.1e-49 168.3 18.0 1.0 1 0 0 1 1 1 1 Major intrinsic protein Peptidase_S10 PF00450.22 KXS95057.1 - 1.7e-25 90.3 1.0 5.7e-14 52.3 0.3 2.1 2 0 0 2 2 2 2 Serine carboxypeptidase F-box PF00646.33 KXS95058.1 - 0.00067 19.5 0.5 0.0027 17.5 0.0 2.3 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KXS95058.1 - 0.006 16.4 0.1 0.017 15.0 0.1 1.8 1 0 0 1 1 1 1 F-box-like Glyco_hydro_30 PF02055.16 KXS95059.1 - 8.3e-27 94.1 0.4 1.2e-26 93.5 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain MFS_1 PF07690.16 KXS95068.1 - 5.4e-43 147.3 34.6 5.4e-43 147.3 34.6 1.8 3 0 0 3 3 3 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KXS95068.1 - 0.0019 17.2 6.2 0.0019 17.2 6.2 2.0 2 1 0 2 2 2 1 MFS_1 like family Pyr_redox_2 PF07992.14 KXS95069.1 - 3.9e-08 32.9 0.0 1.2e-07 31.2 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXS95069.1 - 8.2e-05 21.9 0.0 0.00024 20.3 0.0 1.6 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KXS95069.1 - 0.0032 16.8 0.0 0.79 8.9 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXS95069.1 - 0.016 15.2 0.0 0.7 9.9 0.0 3.2 4 0 0 4 4 4 0 FAD-NAD(P)-binding DUF3287 PF11690.8 KXS95071.1 - 0.0015 18.3 0.0 0.0029 17.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3287) APP_N PF02177.16 KXS95071.1 - 0.0021 18.4 0.3 0.0045 17.3 0.3 1.5 1 0 0 1 1 1 1 Amyloid A4 N-terminal heparin-binding BLOC1_2 PF10046.9 KXS95071.1 - 0.0064 16.8 1.3 0.011 16.0 1.3 1.3 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 PspA_IM30 PF04012.12 KXS95071.1 - 0.024 14.2 3.1 0.038 13.6 3.1 1.3 1 0 0 1 1 1 0 PspA/IM30 family ZapB PF06005.12 KXS95071.1 - 0.028 14.8 2.9 0.059 13.8 2.9 1.5 1 0 0 1 1 1 0 Cell division protein ZapB UPF0449 PF15136.6 KXS95071.1 - 0.043 14.3 1.8 0.08 13.4 1.8 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 End3 PF12761.7 KXS95071.1 - 0.047 13.9 3.3 0.08 13.1 3.3 1.3 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 DUF3450 PF11932.8 KXS95071.1 - 0.061 12.6 5.2 0.092 12.0 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Sec2p PF06428.11 KXS95071.1 - 0.096 12.7 2.1 0.17 11.9 2.1 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Prefoldin_2 PF01920.20 KXS95071.1 - 0.11 12.4 3.2 0.26 11.2 2.7 1.5 1 1 0 1 1 1 0 Prefoldin subunit Jnk-SapK_ap_N PF09744.9 KXS95071.1 - 0.12 12.6 2.8 0.21 11.8 2.8 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Lin-8 PF03353.15 KXS95071.1 - 0.13 11.8 4.7 0.36 10.4 4.6 1.6 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist ADIP PF11559.8 KXS95071.1 - 0.16 12.1 5.7 0.25 11.4 5.7 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Tropomyosin_1 PF12718.7 KXS95071.1 - 0.17 12.1 3.4 0.27 11.4 3.4 1.2 1 0 0 1 1 1 0 Tropomyosin like TMPIT PF07851.13 KXS95071.1 - 0.25 10.6 0.9 0.35 10.1 0.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein bZIP_1 PF00170.21 KXS95071.1 - 0.26 11.4 1.2 0.57 10.3 1.2 1.5 1 0 0 1 1 1 0 bZIP transcription factor zf-C2H2_11 PF16622.5 KXS95071.1 - 0.4 10.5 5.6 0.066 13.0 1.2 2.0 3 0 0 3 3 1 0 zinc-finger C2H2-type zf-C2H2 PF00096.26 KXS95071.1 - 0.56 10.8 6.3 0.12 12.9 1.6 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF4407 PF14362.6 KXS95071.1 - 1 8.6 3.6 1.6 8.0 3.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-C2H2_4 PF13894.6 KXS95071.1 - 4 8.5 9.1 0.46 11.5 2.2 3.1 4 0 0 4 4 2 0 C2H2-type zinc finger Glyco_hydro_72 PF03198.14 KXS95072.1 - 1.6e-114 382.4 3.3 2e-114 382.1 3.3 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 KXS95072.1 - 1.8e-06 27.6 2.0 1.3e-05 24.8 2.0 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 KXS95072.1 - 0.018 14.2 0.2 0.029 13.5 0.2 1.4 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Aminotran_3 PF00202.21 KXS95073.1 - 1.8e-89 300.2 0.1 2.3e-89 299.9 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KXS95073.1 - 1.1e-05 24.8 0.0 7.6e-05 22.0 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class I and II Adeno_E3_CR2 PF02439.15 KXS95074.1 - 0.0007 19.3 2.4 0.0014 18.3 2.4 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Herpes_gE PF02480.16 KXS95074.1 - 0.0014 17.5 0.0 0.0018 17.1 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.6 KXS95074.1 - 0.0089 16.9 0.2 0.019 15.8 0.2 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SMN PF06003.12 KXS95074.1 - 1.1 8.5 5.7 3.7 6.7 3.2 2.1 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) Golgin_A5 PF09787.9 KXS95075.1 - 0.19 11.2 1.5 0.35 10.3 0.8 1.7 1 1 0 1 1 1 0 Golgin subfamily A member 5 DUF2235 PF09994.9 KXS95077.1 - 4.3e-35 121.5 0.0 5.5e-35 121.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Mito_carr PF00153.27 KXS95078.1 - 1.6e-69 229.9 1.3 5.9e-23 80.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KXS95078.1 - 0.12 11.5 0.1 3.1 6.9 0.0 2.7 3 0 0 3 3 3 0 Gammaproteobacterial serine protease FAD_binding_3 PF01494.19 KXS95079.1 - 2.3e-18 66.6 0.0 4.1e-18 65.8 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 KXS95079.1 - 5.4e-06 26.0 0.1 0.0013 18.1 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXS95079.1 - 9.4e-06 25.8 0.1 3.2e-05 24.1 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXS95079.1 - 0.00015 21.1 0.0 0.0006 19.1 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXS95079.1 - 0.0015 17.9 0.5 0.021 14.1 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXS95079.1 - 0.0017 17.5 0.1 0.018 14.1 0.1 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein Trp_halogenase PF04820.14 KXS95079.1 - 0.0026 16.7 0.1 0.04 12.8 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase DAO PF01266.24 KXS95079.1 - 0.0039 16.8 0.1 0.0078 15.8 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXS95079.1 - 0.005 16.1 0.0 0.0085 15.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 KXS95079.1 - 0.0059 17.2 0.4 0.11 13.1 0.1 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXS95079.1 - 0.022 13.8 0.1 0.032 13.3 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain DUF2204 PF09970.9 KXS95079.1 - 0.033 13.8 0.0 0.062 12.9 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF2204) MIP PF00230.20 KXS95082.1 - 2.5e-47 161.5 19.0 3.1e-47 161.2 19.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein F-box PF00646.33 KXS95083.1 - 0.046 13.6 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 F-box domain NIPSNAP PF07978.13 KXS95084.1 - 1.2e-41 141.0 5.0 6.2e-31 106.7 0.1 2.6 3 0 0 3 3 3 2 NIPSNAP zf-RING_2 PF13639.6 KXS95085.1 - 1.1e-12 48.1 5.3 1.7e-12 47.4 5.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXS95085.1 - 2.3e-09 36.9 3.9 3.7e-09 36.3 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXS95085.1 - 1.2e-08 35.1 3.4 3e-08 33.8 3.4 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KXS95085.1 - 1.2e-08 34.6 3.1 2e-08 33.9 3.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXS95085.1 - 3.3e-08 33.1 2.2 3.3e-08 33.1 2.2 1.8 2 0 0 2 2 2 1 RING-like zinc finger PA PF02225.22 KXS95085.1 - 1.9e-07 31.0 0.0 5.1e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 PA domain zf-RING_5 PF14634.6 KXS95085.1 - 5.7e-07 29.4 2.4 9.3e-07 28.7 2.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXS95085.1 - 6e-06 26.2 1.7 1.2e-05 25.2 0.3 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KXS95085.1 - 7e-06 25.8 3.1 1e-05 25.2 3.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KXS95085.1 - 0.00068 19.6 0.4 0.0013 18.7 0.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KXS95085.1 - 0.0064 16.3 2.6 0.011 15.6 2.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KXS95085.1 - 0.025 14.2 3.0 0.05 13.2 3.0 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 KXS95085.1 - 0.099 12.8 4.0 0.22 11.7 4.0 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 KXS95085.1 - 0.15 12.3 2.3 0.4 10.9 2.3 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 KXS95085.1 - 0.25 11.5 3.0 0.51 10.5 2.8 1.7 1 1 0 1 1 1 0 RING-variant domain zf-Nse PF11789.8 KXS95085.1 - 0.99 9.3 2.4 1.9 8.4 2.4 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.29 KXS95085.1 - 1 9.3 2.4 1.9 8.4 2.4 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 KXS95085.1 - 1.2 9.5 3.2 2.2 8.7 3.2 1.4 1 0 0 1 1 1 0 RING-like domain COesterase PF00135.28 KXS95087.1 - 1.5e-30 106.6 0.0 6.7e-28 97.8 0.0 2.9 2 1 1 3 3 3 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KXS95087.1 - 0.00061 19.7 0.1 0.0012 18.8 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Pheromone PF08015.11 KXS95088.1 - 0.58 11.2 5.8 10 7.2 0.3 2.8 3 0 0 3 3 3 0 Fungal mating-type pheromone ApbA_C PF08546.11 KXS95089.1 - 7.6e-27 94.0 0.0 1.4e-26 93.1 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KXS95089.1 - 9e-26 90.3 0.0 1.2e-25 89.9 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 KXS95089.1 - 0.064 13.7 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 KXS95089.1 - 0.1 11.8 0.6 0.14 11.4 0.6 1.2 1 0 0 1 1 1 0 FAD binding domain ThiF PF00899.21 KXS95089.1 - 0.32 10.3 2.8 0.58 9.5 2.8 1.3 1 0 0 1 1 1 0 ThiF family Acyl-CoA_dh_2 PF08028.11 KXS95090.1 - 1.2e-11 45.0 2.5 8.3e-06 26.1 0.6 2.3 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KXS95090.1 - 3.5e-07 30.9 0.0 7.3e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KXS95090.1 - 1e-05 25.6 0.0 2.4e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KXS95090.1 - 0.003 17.8 1.8 0.0058 16.8 0.1 2.3 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain CIA30 PF08547.12 KXS95091.1 - 1e-40 139.4 0.0 1.3e-40 139.0 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) SGBP_B_XBD PF18329.1 KXS95091.1 - 0.0012 18.8 0.0 0.0047 16.9 0.0 1.8 2 0 0 2 2 2 1 Surface glycan-binding protein B xyloglucan binding domain PhyH PF05721.13 KXS95093.1 - 3.1e-19 70.1 0.0 4.3e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) bZIP_1 PF00170.21 KXS95095.1 - 3.3e-05 23.9 9.7 0.00039 20.5 5.8 2.5 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KXS95095.1 - 0.0026 17.8 9.0 0.0031 17.6 2.2 2.5 2 0 0 2 2 2 1 Basic region leucine zipper DUF1635 PF07795.11 KXS95095.1 - 0.011 15.6 1.8 0.011 15.6 1.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1635) MOFRL PF05161.13 KXS95095.1 - 0.049 13.8 0.1 1.9 8.7 0.1 2.7 2 1 1 3 3 3 0 MOFRL family HALZ PF02183.18 KXS95095.1 - 0.067 13.4 1.4 0.68 10.2 0.1 2.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper bZIP_Maf PF03131.17 KXS95095.1 - 0.16 12.5 8.8 0.18 12.4 7.4 1.8 1 1 0 1 1 1 0 bZIP Maf transcription factor BRE1 PF08647.11 KXS95095.1 - 2.6 8.2 10.9 1.4 9.0 8.2 2.0 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Asn_synthase PF00733.21 KXS95096.1 - 5.8e-65 220.3 0.0 8.2e-65 219.8 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 KXS95096.1 - 2e-37 127.8 0.0 3.5e-37 127.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KXS95096.1 - 1.5e-35 122.3 0.0 3e-35 121.3 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KXS95096.1 - 2e-06 27.4 0.0 4.2e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 KXS95096.1 - 0.0049 16.0 0.0 0.0081 15.3 0.0 1.3 1 0 0 1 1 1 1 NAD synthase tRNA_Me_trans PF03054.16 KXS95096.1 - 0.18 10.5 0.0 0.29 9.9 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase MFS_1 PF07690.16 KXS95098.1 - 2.9e-30 105.4 27.0 5.9e-30 104.4 26.7 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KXS95098.1 - 0.013 13.8 10.2 0.022 13.0 1.5 3.1 2 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Rax2 PF12768.7 KXS95098.1 - 0.063 12.7 0.0 0.1 12.0 0.0 1.4 1 1 0 1 1 1 0 Cortical protein marker for cell polarity ESSS PF10183.9 KXS95098.1 - 0.089 13.0 0.4 1 9.6 0.0 2.8 2 1 1 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF4351 PF14261.6 KXS95099.1 - 0.1 12.7 0.1 0.27 11.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4351) 14-3-3 PF00244.20 KXS95100.1 - 2.6e-97 324.7 0.3 3e-97 324.5 0.3 1.0 1 0 0 1 1 1 1 14-3-3 protein Glyco_transf_8 PF01501.20 KXS95101.1 - 6.1e-05 22.7 0.0 0.00015 21.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 8 Pkinase PF00069.25 KXS95103.1 - 1.7e-65 221.0 0.0 2.7e-65 220.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS95103.1 - 9.5e-39 133.2 0.0 1.4e-38 132.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS95103.1 - 4.4e-08 32.8 0.0 3.3e-07 29.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KXS95103.1 - 7.4e-05 21.8 0.1 0.00016 20.7 0.1 1.5 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KXS95103.1 - 0.00024 21.1 4.7 0.023 14.6 0.1 3.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 KXS95103.1 - 0.0058 16.0 0.1 0.034 13.5 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ferlin_C PF16165.5 KXS95103.1 - 0.0077 16.2 0.7 0.019 14.9 0.7 1.6 1 0 0 1 1 1 1 Ferlin C-terminus RIO1 PF01163.22 KXS95103.1 - 0.14 11.7 0.0 0.14 11.7 0.0 1.7 2 0 0 2 2 2 0 RIO1 family Seadorna_VP7 PF07387.11 KXS95103.1 - 0.24 10.4 0.0 0.36 9.8 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 GST_N PF02798.20 KXS95105.1 - 3.6e-12 46.5 0.0 5.4e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXS95105.1 - 1.9e-11 44.0 0.0 3.1e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXS95105.1 - 9.5e-10 38.6 0.0 1.4e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXS95105.1 - 1.1e-07 31.7 0.0 2e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KXS95105.1 - 2.4e-06 27.8 0.0 3.8e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXS95105.1 - 7.8e-06 26.1 0.0 1.4e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain zf-C2H2 PF00096.26 KXS95106.1 - 2e-12 46.8 14.1 7.6e-07 29.2 1.5 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS95106.1 - 2.9e-08 33.9 11.7 0.00049 20.7 0.7 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXS95106.1 - 1.4e-06 28.5 13.9 9.5e-06 25.8 6.2 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KXS95106.1 - 1.2e-05 25.5 5.6 0.012 15.9 1.1 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXS95106.1 - 3.3e-05 24.1 5.1 0.0063 16.9 0.3 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KXS95106.1 - 0.002 18.1 9.9 0.071 13.1 1.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-LYAR PF08790.11 KXS95106.1 - 0.015 15.2 4.0 0.52 10.3 0.6 2.6 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf_C2H2_ZHX PF18387.1 KXS95106.1 - 0.021 14.4 3.8 0.8 9.4 0.7 2.5 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain LIM PF00412.22 KXS95106.1 - 0.11 12.8 4.1 0.26 11.5 4.1 1.6 1 0 0 1 1 1 0 LIM domain zf-UBR PF02207.20 KXS95106.1 - 0.13 12.4 1.8 0.27 11.4 1.8 1.4 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) zf_UBZ PF18439.1 KXS95106.1 - 0.32 10.6 2.4 0.84 9.3 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_3rep PF18868.1 KXS95106.1 - 0.42 11.3 4.4 2.7 8.7 0.8 2.6 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 KXS95106.1 - 1.4 8.7 10.1 4.1 7.3 0.2 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-BED PF02892.15 KXS95106.1 - 4.2 7.5 7.0 2.9 8.0 3.3 2.2 1 1 1 2 2 2 0 BED zinc finger zf-C2HE PF16278.5 KXS95106.1 - 7.4 7.1 7.3 29 5.2 0.9 2.5 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Clathrin PF00637.20 KXS95108.1 - 4.1e-196 642.7 32.9 5.3e-32 110.7 0.3 7.8 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 KXS95108.1 - 1.5e-30 104.0 0.1 4.3e-08 33.1 0.0 6.6 6 0 0 6 6 6 5 Clathrin propeller repeat Clathrin_H_link PF13838.6 KXS95108.1 - 2.1e-30 104.4 3.5 4.8e-30 103.3 0.8 3.1 2 1 1 3 3 3 1 Clathrin-H-link Vps39_1 PF10366.9 KXS95108.1 - 4.5e-06 26.9 6.0 3.9 7.8 0.0 6.3 4 1 1 5 5 5 2 Vacuolar sorting protein 39 domain 1 Clathrin-link PF09268.10 KXS95108.1 - 0.00016 21.0 0.2 0.00044 19.5 0.2 1.9 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.14 KXS95108.1 - 0.0068 15.5 4.8 0.16 11.0 0.5 4.1 5 0 0 5 5 5 1 Coatomer WD associated region TPR_7 PF13176.6 KXS95108.1 - 0.034 14.2 5.9 48 4.3 0.0 7.1 9 0 0 9 9 8 0 Tetratricopeptide repeat VapB_antitoxin PF09957.9 KXS95108.1 - 0.097 12.6 0.2 0.51 10.3 0.0 2.4 3 0 0 3 3 2 0 Bacterial antitoxin of type II TA system, VapB TPR_14 PF13428.6 KXS95108.1 - 0.14 13.0 18.5 2.5 9.1 0.1 8.6 11 0 0 11 11 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXS95108.1 - 0.28 11.4 5.3 7.9 6.9 0.1 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXS95108.1 - 0.38 11.1 0.0 0.38 11.1 0.0 5.3 7 0 0 7 7 4 0 Tetratricopeptide repeat DUF1720 PF08226.11 KXS95108.1 - 0.45 11.0 12.9 0.14 12.6 8.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1720) V-SNARE PF05008.15 KXS95115.1 - 1e-19 70.7 5.6 1e-19 70.7 5.6 2.1 3 0 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 KXS95115.1 - 4.4e-17 62.1 5.6 4.4e-17 62.1 5.6 2.5 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KXS95115.1 - 0.00064 19.6 3.0 0.0017 18.2 0.2 2.6 2 2 0 2 2 2 1 Sec20 Fusion_gly PF00523.18 KXS95115.1 - 0.0025 16.1 2.4 0.0065 14.8 0.2 2.2 2 0 0 2 2 2 1 Fusion glycoprotein F0 Spectrin PF00435.21 KXS95115.1 - 0.11 13.0 8.1 0.061 13.8 3.3 2.5 2 1 1 3 3 3 0 Spectrin repeat Synaptobrevin PF00957.21 KXS95115.1 - 0.14 12.0 4.2 0.3 10.9 2.4 2.3 1 1 1 2 2 2 0 Synaptobrevin RIFIN PF02009.16 KXS95115.1 - 0.2 11.5 4.4 0.42 10.5 4.4 1.6 1 1 0 1 1 1 0 Rifin DUF4407 PF14362.6 KXS95115.1 - 0.42 9.9 13.7 0.85 8.9 13.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF349 PF03993.12 KXS95115.1 - 5.4 7.4 8.9 3.1 8.2 1.1 2.4 1 1 1 2 2 2 0 Domain of Unknown Function (DUF349) p450 PF00067.22 KXS95116.1 - 1.7e-60 205.1 0.0 2.4e-60 204.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 KXS95117.1 - 9.7e-44 149.7 28.3 1.7e-37 129.2 15.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KXS95117.1 - 2.6e-05 22.7 1.1 0.0027 16.1 2.5 2.8 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.6 KXS95117.1 - 9.4e-05 21.1 14.9 0.02 13.5 1.9 2.5 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_4 PF06779.14 KXS95117.1 - 0.0017 17.7 16.5 0.0018 17.6 4.2 2.9 2 1 1 3 3 3 2 Uncharacterised MFS-type transporter YbfB VIT1 PF01988.19 KXS95117.1 - 0.83 9.5 5.0 20 4.9 0.2 3.2 3 1 0 3 3 3 0 VIT family Fungal_trans_2 PF11951.8 KXS95118.1 - 5.5e-36 124.2 3.8 4.6e-35 121.1 3.8 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS95118.1 - 0.00016 21.7 9.4 0.00016 21.7 9.4 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXS95119.1 - 5.5e-36 124.2 3.8 4.6e-35 121.1 3.8 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS95119.1 - 0.00016 21.7 9.4 0.00016 21.7 9.4 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UPF0158 PF03682.13 KXS95120.1 - 0.075 13.0 0.1 15 5.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0158) RNA_pol_Rbc25 PF08292.12 KXS95121.1 - 5.3e-26 91.4 0.1 7.1e-26 90.9 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 KXS95121.1 - 2.8e-13 50.0 0.1 4.1e-13 49.5 0.1 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RINGv PF12906.7 KXS95122.1 - 1.4e-09 37.9 5.4 4.4e-09 36.3 1.8 2.3 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.6 KXS95122.1 - 0.0014 18.9 4.4 0.043 14.1 1.3 2.2 2 0 0 2 2 2 1 Ring finger domain ABC2_membrane_2 PF12679.7 KXS95122.1 - 0.0029 17.0 0.4 0.004 16.5 0.4 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein zf-MIZ PF02891.20 KXS95122.1 - 0.0047 16.6 1.9 0.009 15.7 1.9 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger PHD_4 PF16866.5 KXS95122.1 - 0.014 15.4 3.7 0.08 13.0 1.7 2.5 2 0 0 2 2 2 0 PHD-finger DUF4079 PF13301.6 KXS95122.1 - 0.03 14.5 0.0 0.33 11.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) Claudin_2 PF13903.6 KXS95122.1 - 0.048 13.4 0.1 4.4 7.0 0.0 2.3 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Pex14_N PF04695.13 KXS95122.1 - 0.07 13.8 3.6 0.13 12.9 3.6 1.5 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-RING_4 PF14570.6 KXS95122.1 - 0.87 9.4 7.6 0.24 11.2 3.9 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain PHD PF00628.29 KXS95122.1 - 1.7 8.6 7.4 0.2 11.6 2.9 1.7 2 0 0 2 2 2 0 PHD-finger zf-CCCH PF00642.24 KXS95123.1 - 7.2e-08 32.1 4.5 1.1e-07 31.5 4.5 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) NUFIP1 PF10453.9 KXS95123.1 - 2.3e-06 27.3 0.4 2.3e-06 27.3 0.4 2.0 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf_CCCH_4 PF18345.1 KXS95123.1 - 0.00015 21.7 6.1 0.00026 20.9 6.1 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 KXS95123.1 - 0.0027 17.5 4.4 0.0046 16.7 4.4 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 KXS95123.1 - 0.0085 16.8 0.0 0.022 15.4 0.0 1.7 1 0 0 1 1 1 1 Torus domain zf-CCCH_2 PF14608.6 KXS95123.1 - 0.13 12.8 5.1 0.21 12.1 5.1 1.3 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger GREB1 PF15782.5 KXS95123.1 - 2 5.4 6.4 2.9 4.9 6.4 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4246 PF14033.6 KXS95124.1 - 1.9e-162 541.5 0.0 2.2e-162 541.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.6 KXS95124.1 - 0.13 12.6 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Peroxidase_2 PF01328.17 KXS95125.1 - 2.2e-39 136.0 0.0 2.9e-39 135.5 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 FMO-like PF00743.19 KXS95126.1 - 1.9e-18 66.2 0.2 5.4e-18 64.7 0.0 1.7 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KXS95126.1 - 1.5e-10 40.8 0.0 2e-08 33.8 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXS95126.1 - 4.8e-10 39.5 0.0 1.3e-09 38.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXS95126.1 - 1.4e-07 31.1 0.0 3.7e-05 23.1 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXS95126.1 - 2.2e-07 30.3 0.0 6.8e-05 22.2 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KXS95126.1 - 2.3e-05 24.2 0.0 0.15 11.6 0.0 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXS95126.1 - 0.0002 21.4 0.0 0.0082 16.1 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 KXS95126.1 - 0.00072 19.0 0.0 0.065 12.5 0.0 2.9 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase Thi4 PF01946.17 KXS95126.1 - 0.013 14.7 0.0 4.6 6.4 0.0 2.2 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 KXS95126.1 - 0.025 15.1 0.0 0.36 11.4 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Patatin PF01734.22 KXS95128.1 - 3.2e-16 60.1 0.0 1.8e-15 57.7 0.0 2.2 1 1 0 1 1 1 1 Patatin-like phospholipase Transpos_assoc PF13963.6 KXS95128.1 - 0.045 14.1 0.4 1 9.7 0.1 2.5 1 1 1 2 2 2 0 Transposase-associated domain Patatin PF01734.22 KXS95129.1 - 3.2e-16 60.1 0.0 1.8e-15 57.7 0.0 2.2 1 1 0 1 1 1 1 Patatin-like phospholipase Transpos_assoc PF13963.6 KXS95129.1 - 0.045 14.1 0.4 1 9.7 0.1 2.5 1 1 1 2 2 2 0 Transposase-associated domain ESCRT-II PF05871.12 KXS95130.1 - 2.5e-50 170.3 0.1 4.3e-50 169.6 0.1 1.3 1 0 0 1 1 1 1 ESCRT-II complex subunit ATP-grasp_3 PF02655.14 KXS95131.1 - 0.00019 21.5 0.0 0.00053 20.1 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain DUF4682 PF15733.5 KXS95131.1 - 0.13 12.8 0.5 0.24 12.0 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4682) Abhydrolase_6 PF12697.7 KXS95132.1 - 4.2e-11 43.9 5.3 2.4e-10 41.4 5.3 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXS95132.1 - 5.4e-09 35.7 0.0 8.9e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXS95132.1 - 0.011 15.4 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 KXS95132.1 - 0.029 13.3 0.0 0.048 12.6 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Ndr PF03096.14 KXS95132.1 - 0.048 12.4 0.0 0.075 11.7 0.0 1.2 1 0 0 1 1 1 0 Ndr family Esterase PF00756.20 KXS95132.1 - 0.07 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative esterase MFS_1 PF07690.16 KXS95133.1 - 2.2e-36 125.5 34.3 2.2e-36 125.5 34.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS95133.1 - 8.1e-05 21.7 8.2 8.1e-05 21.7 8.2 2.3 2 1 1 3 3 3 1 Sugar (and other) transporter UAF_Rrn10 PF05234.11 KXS95134.1 - 2.7e-05 24.4 0.0 4.1e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 UAF complex subunit Rrn10 zf-CCCH PF00642.24 KXS95135.1 - 5.4e-06 26.2 8.6 0.00025 20.9 1.1 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KXS95135.1 - 5.9e-05 23.7 2.0 0.00032 21.4 2.0 2.3 1 0 0 1 1 1 1 Torus domain zf-CCCH_4 PF18044.1 KXS95135.1 - 0.00015 21.5 1.2 0.00015 21.5 1.2 2.3 2 0 0 2 2 2 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 KXS95135.1 - 0.3 11.6 8.9 2.9 8.5 1.1 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KXS95135.1 - 1.4 9.2 8.1 4.8 7.4 1.3 2.7 2 1 1 3 3 3 0 Zinc-finger containing family zf_CCCH_4 PF18345.1 KXS95135.1 - 5.2 7.3 20.7 0.038 14.0 4.7 3.2 3 0 0 3 3 3 0 Zinc finger domain Proteasome PF00227.26 KXS95136.1 - 2.2e-56 190.4 0.0 6.4e-32 110.6 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 KXS95136.1 - 9.6e-11 41.2 0.1 3.2e-10 39.5 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Aconitase_B_N PF11791.8 KXS95137.1 - 0.021 14.9 0.2 0.05 13.7 0.2 1.7 1 0 0 1 1 1 0 Aconitate B N-terminal domain HAUS4 PF14735.6 KXS95137.1 - 0.032 13.9 13.3 0.0084 15.8 7.8 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 4 DUF4047 PF13256.6 KXS95137.1 - 0.17 12.1 2.0 0.21 11.8 0.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4047) Focal_AT PF03623.13 KXS95137.1 - 0.35 10.8 5.3 0.3 11.1 2.9 2.0 2 0 0 2 2 2 0 Focal adhesion targeting region A1_Propeptide PF07966.12 KXS95137.1 - 0.57 10.1 3.9 1.4 8.8 0.8 2.5 2 0 0 2 2 2 0 A1 Propeptide Ku_C PF03730.14 KXS95137.1 - 0.61 10.8 6.7 17 6.2 0.1 3.7 4 0 0 4 4 4 0 Ku70/Ku80 C-terminal arm kleA_kleC PF17383.2 KXS95137.1 - 2 8.8 4.7 11 6.5 0.4 3.0 3 0 0 3 3 3 0 Uncharacterized KorC regulated protein A Proteasome PF00227.26 KXS95138.1 - 2.2e-56 190.4 0.0 6.4e-32 110.6 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 KXS95138.1 - 9.6e-11 41.2 0.1 3.2e-10 39.5 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Pkinase PF00069.25 KXS95139.1 - 8.9e-08 31.8 0.0 4.9e-07 29.4 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain PHD PF00628.29 KXS95139.1 - 1.1e-06 28.5 7.6 2.7e-06 27.2 7.6 1.8 1 0 0 1 1 1 1 PHD-finger APH PF01636.23 KXS95139.1 - 0.0046 16.9 3.8 0.82 9.5 3.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family zf-HC5HC2H PF13771.6 KXS95139.1 - 0.0072 16.6 0.8 0.021 15.0 0.8 1.8 1 0 0 1 1 1 1 PHD-like zinc-binding domain PHD_2 PF13831.6 KXS95139.1 - 0.022 14.3 2.2 0.053 13.1 2.2 1.7 1 0 0 1 1 1 0 PHD-finger WaaY PF06176.11 KXS95139.1 - 0.03 13.9 0.0 0.056 13.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) zf-C2HCIx2C PF10782.9 KXS95139.1 - 0.09 12.7 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger zf-HC5HC2H_2 PF13832.6 KXS95139.1 - 0.18 12.0 1.5 0.37 11.0 0.2 2.1 2 0 0 2 2 2 0 PHD-zinc-finger like domain CDC45 PF02724.14 KXS95139.1 - 0.38 9.0 17.8 1 7.6 0.5 2.1 2 0 0 2 2 2 0 CDC45-like protein Tannase PF07519.11 KXS95140.1 - 4.7e-103 345.6 0.1 6.3e-103 345.2 0.1 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 KXS95140.1 - 0.039 13.2 0.0 0.21 10.8 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 SpoIIE PF07228.12 KXS95141.1 - 7.6e-13 48.8 0.0 4e-12 46.4 0.0 1.9 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 KXS95141.1 - 2e-10 40.8 0.0 0.0003 20.5 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C Ammonium_transp PF00909.21 KXS95142.1 - 4.1e-118 394.6 30.8 4.7e-118 394.4 30.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF441 PF04284.13 KXS95142.1 - 0.12 12.4 0.1 0.12 12.4 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF441) DUF4223 PF13978.6 KXS95142.1 - 0.28 11.2 1.8 0.41 10.7 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4223) Sel1 PF08238.12 KXS95144.1 - 2.8e-12 46.9 1.8 0.00013 22.5 0.1 3.8 4 0 0 4 4 4 3 Sel1 repeat TPR_6 PF13174.6 KXS95144.1 - 0.28 11.9 1.7 32 5.4 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Sel1 PF08238.12 KXS95145.1 - 1.3e-11 44.8 1.5 0.0001 22.9 0.1 3.7 4 0 0 4 4 4 3 Sel1 repeat TPR_6 PF13174.6 KXS95145.1 - 0.25 12.1 2.1 25 5.8 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3292 PF11696.8 KXS95146.1 - 0.067 11.6 0.0 0.067 11.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) zf-CCCH PF00642.24 KXS95147.1 - 1.1e-07 31.6 26.9 5.8e-06 26.1 2.8 5.6 5 1 1 6 6 6 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KXS95147.1 - 2e-07 30.8 28.5 0.00019 21.4 2.7 6.2 5 2 1 6 6 6 3 Zinc finger domain zf-CCCH_4 PF18044.1 KXS95147.1 - 0.00016 21.4 2.0 0.00016 21.4 2.0 5.1 5 0 0 5 5 5 2 CCCH-type zinc finger zf-CCCH_3 PF15663.5 KXS95147.1 - 0.0098 16.1 1.3 0.0098 16.1 1.3 3.3 2 1 1 3 3 3 1 Zinc-finger containing family Torus PF16131.5 KXS95147.1 - 1.4 9.7 23.0 0.42 11.3 1.6 4.9 1 1 4 5 5 5 0 Torus domain DUF3597 PF12200.8 KXS95147.1 - 4.2 7.9 9.2 1.1 9.8 0.5 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3597) Peptidase_M6 PF05547.11 KXS95148.1 - 0.096 11.0 0.1 0.13 10.5 0.1 1.2 1 0 0 1 1 1 0 Immune inhibitor A peptidase M6 bZIP_1 PF00170.21 KXS95149.1 - 7.4e-08 32.4 22.3 9.8e-08 32.0 17.1 2.6 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KXS95149.1 - 5.1e-06 26.5 14.6 5.1e-06 26.5 14.6 3.1 3 0 0 3 3 3 1 Basic region leucine zipper bZIP_Maf PF03131.17 KXS95149.1 - 5.9e-05 23.5 18.0 5.9e-05 23.5 18.0 3.2 2 1 1 3 3 3 1 bZIP Maf transcription factor PV-1 PF06637.11 KXS95149.1 - 0.0073 15.2 6.8 0.014 14.3 6.8 1.4 1 0 0 1 1 1 1 PV-1 protein (PLVAP) 5_nucleotid PF05761.14 KXS95149.1 - 3.2 6.6 9.5 5.8 5.7 9.5 1.3 1 0 0 1 1 1 0 5' nucleotidase family Tho2 PF11262.8 KXS95149.1 - 3.4 6.8 17.9 0.016 14.4 8.7 1.8 2 1 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DegT_DnrJ_EryC1 PF01041.17 KXS95149.1 - 7.2 5.8 7.3 11 5.1 7.3 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Sortilin-Vps10 PF15902.5 KXS95151.1 - 3.8e-297 985.1 20.1 9.7e-155 515.7 6.1 2.2 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 KXS95151.1 - 4.4e-93 310.3 24.4 1.2e-46 159.1 10.6 2.5 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 KXS95151.1 - 2.5e-13 47.9 41.4 0.17 12.0 0.1 11.6 11 0 0 11 11 11 8 BNR/Asp-box repeat PSII_BNR PF14870.6 KXS95151.1 - 0.0001 21.7 8.5 0.021 14.1 0.2 4.7 4 1 1 5 5 5 2 Photosynthesis system II assembly factor YCF48 BNR_6 PF15899.5 KXS95151.1 - 0.017 15.1 4.2 83 3.7 0.0 5.9 6 0 0 6 6 6 0 BNR-Asp box repeat DUF2561 PF10812.8 KXS95151.1 - 0.02 14.9 0.0 0.036 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) CHB_HEX_C PF03174.13 KXS95151.1 - 0.037 14.0 9.7 4.6 7.3 0.0 6.4 8 0 0 8 8 8 0 Chitobiase/beta-hexosaminidase C-terminal domain WD40 PF00400.32 KXS95152.1 - 2.4e-43 145.2 17.3 5e-08 33.5 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS95152.1 - 2.5e-06 27.7 1.1 1 9.7 0.2 5.3 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KXS95152.1 - 0.0073 15.9 0.2 0.48 10.0 0.0 3.1 1 1 3 4 4 4 2 PQQ-like domain Nup160 PF11715.8 KXS95152.1 - 0.018 13.7 1.0 6 5.4 0.1 3.2 1 1 2 3 3 3 0 Nucleoporin Nup120/160 WD40_like PF17005.5 KXS95152.1 - 0.14 11.5 0.0 0.46 9.8 0.0 1.8 2 1 0 2 2 2 0 WD40-like domain Ribosomal_L21p PF00829.21 KXS95153.1 - 1.3e-05 25.4 0.4 0.35 11.2 0.0 2.6 2 0 0 2 2 2 2 Ribosomal prokaryotic L21 protein GOLGA2L5 PF15070.6 KXS95153.1 - 0.087 11.5 0.1 1.6 7.3 0.0 2.1 2 0 0 2 2 2 0 Putative golgin subfamily A member 2-like protein 5 Amino_oxidase PF01593.24 KXS95154.1 - 6.8e-63 213.5 0.1 8.5e-63 213.2 0.1 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXS95154.1 - 2.1e-11 43.8 0.3 5.5e-11 42.5 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KXS95154.1 - 2.7e-07 30.3 1.7 4.2e-07 29.7 1.7 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 KXS95154.1 - 6.3e-07 29.3 1.4 1.5e-06 28.1 1.4 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXS95154.1 - 3e-06 26.6 2.9 3.3e-06 26.4 1.9 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KXS95154.1 - 1.6e-05 23.8 0.4 0.00034 19.5 0.3 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 KXS95154.1 - 2.4e-05 23.8 0.4 3.9e-05 23.1 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KXS95154.1 - 2.4e-05 24.8 0.6 5.6e-05 23.6 0.6 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXS95154.1 - 2.7e-05 23.6 0.1 0.0001 21.7 0.2 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXS95154.1 - 3.7e-05 23.1 0.1 0.026 13.8 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXS95154.1 - 8.2e-05 22.0 0.8 0.00012 21.5 0.1 1.5 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 KXS95154.1 - 0.00038 20.5 0.1 0.06 13.3 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding GIDA PF01134.22 KXS95154.1 - 0.00097 18.3 0.3 0.0018 17.4 0.3 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KXS95154.1 - 0.0039 16.5 1.2 0.0084 15.4 1.2 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 KXS95154.1 - 0.03 13.4 0.5 0.062 12.3 0.5 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein WD40 PF00400.32 KXS95155.1 - 4.4e-33 112.8 19.2 4e-08 33.8 0.5 7.8 7 1 0 7 7 7 6 WD domain, G-beta repeat PRP4 PF08799.11 KXS95155.1 - 3.7e-11 42.4 8.6 7e-11 41.5 8.6 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 KXS95155.1 - 9.3e-11 41.9 0.1 0.2 12.0 0.0 5.4 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXS95155.1 - 0.0047 16.8 0.0 0.34 10.7 0.0 2.9 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A FMN_dh PF01070.18 KXS95166.1 - 3.3e-111 371.7 0.0 4e-111 371.4 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KXS95166.1 - 2.7e-18 65.9 0.0 6.1e-18 64.7 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KXS95166.1 - 0.0018 17.5 0.0 0.003 16.7 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase Nup54_C PF18437.1 KXS95166.1 - 0.0037 17.1 0.1 0.0073 16.2 0.1 1.4 1 0 0 1 1 1 1 Nup54 C-terminal interacting domain NMO PF03060.15 KXS95166.1 - 0.0062 16.0 0.0 0.013 15.0 0.0 1.4 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KXS95166.1 - 0.025 13.6 0.0 0.044 12.8 0.0 1.4 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain BtpA PF03437.15 KXS95166.1 - 0.037 13.4 0.0 0.085 12.3 0.0 1.5 1 0 0 1 1 1 0 BtpA family Peptidase_C78 PF07910.13 KXS95167.1 - 1.6e-44 151.9 0.0 2.2e-44 151.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 DRE2_N PF16803.5 KXS95168.1 - 3.6e-40 137.2 0.0 5.3e-40 136.7 0.0 1.2 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus CIAPIN1 PF05093.13 KXS95168.1 - 4.5e-40 136.2 3.5 9.4e-40 135.2 3.5 1.5 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Aconitase PF00330.20 KXS95169.1 - 5.1e-142 474.1 0.0 6.5e-142 473.8 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KXS95169.1 - 9.1e-41 139.3 0.0 1.5e-40 138.6 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain ABC_membrane PF00664.23 KXS95170.1 - 1.4e-84 284.1 33.0 7.2e-43 147.2 15.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXS95170.1 - 1.1e-67 226.8 0.0 3e-33 115.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KXS95170.1 - 1.7e-12 47.3 2.0 0.0026 17.3 0.0 4.1 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KXS95170.1 - 2.7e-10 40.4 0.0 0.0003 20.8 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KXS95170.1 - 1.6e-09 38.4 0.7 0.0015 18.9 0.1 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KXS95170.1 - 1.9e-08 34.7 0.3 0.0063 16.8 0.1 3.7 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KXS95170.1 - 7.8e-07 28.7 4.2 0.017 14.8 0.4 3.0 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_21 PF13304.6 KXS95170.1 - 1.4e-06 28.4 0.0 0.21 11.4 0.0 4.0 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC_ATPase PF09818.9 KXS95170.1 - 1.9e-06 27.0 0.4 0.14 11.0 0.0 3.5 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_30 PF13604.6 KXS95170.1 - 9.5e-06 25.5 0.0 0.25 11.1 0.1 4.1 3 1 0 3 3 3 1 AAA domain AAA_15 PF13175.6 KXS95170.1 - 3e-05 23.9 0.0 0.044 13.5 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain Rad17 PF03215.15 KXS95170.1 - 3.5e-05 23.8 0.1 0.39 10.6 0.0 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain AAA PF00004.29 KXS95170.1 - 3.5e-05 24.2 0.2 5.4 7.4 0.0 4.4 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KXS95170.1 - 4.5e-05 23.1 0.1 0.12 11.9 0.2 3.1 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.14 KXS95170.1 - 5.6e-05 23.2 0.3 0.49 10.4 0.0 3.2 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KXS95170.1 - 6.8e-05 23.0 0.0 0.13 12.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KXS95170.1 - 0.0002 21.7 0.0 0.51 10.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KXS95170.1 - 0.00026 20.3 0.0 0.17 11.1 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin SbcCD_C PF13558.6 KXS95170.1 - 0.00052 20.2 0.5 0.77 10.0 0.0 3.7 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 KXS95170.1 - 0.00085 19.9 0.0 2.2 8.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KXS95170.1 - 0.0009 19.6 0.1 1.6 9.1 0.0 2.9 2 0 0 2 2 2 1 RNA helicase AAA_7 PF12775.7 KXS95170.1 - 0.0016 18.0 0.0 2.2 7.7 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_23 PF13476.6 KXS95170.1 - 0.0017 18.9 2.6 2 8.9 0.6 3.2 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 KXS95170.1 - 0.007 16.4 0.0 4.5 7.4 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase NB-ARC PF00931.22 KXS95170.1 - 0.01 15.0 0.1 0.83 8.8 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain IstB_IS21 PF01695.17 KXS95170.1 - 0.017 14.9 0.1 11 5.7 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein NACHT PF05729.12 KXS95170.1 - 0.02 14.8 0.2 11 5.9 0.0 2.9 2 0 0 2 2 2 0 NACHT domain AAA_14 PF13173.6 KXS95170.1 - 0.034 14.2 0.0 18 5.4 0.0 3.4 4 0 0 4 4 4 0 AAA domain SRP54 PF00448.22 KXS95170.1 - 0.035 13.7 0.0 3 7.4 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.17 KXS95170.1 - 0.077 12.8 0.0 15 5.3 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 KXS95170.1 - 0.11 12.2 0.1 20 4.8 0.1 2.5 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 KXS95170.1 - 0.11 11.7 0.0 2.9 7.0 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit ATP-synt_ab PF00006.25 KXS95170.1 - 0.16 11.6 0.9 3.6 7.2 0.0 3.3 4 0 0 4 4 3 0 ATP synthase alpha/beta family, nucleotide-binding domain TMEM208_SND2 PF05620.11 KXS95171.1 - 1.6e-56 190.7 1.1 1.9e-56 190.5 1.1 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 RNA_Me_trans PF04252.13 KXS95172.1 - 4e-73 245.3 0.0 4.6e-73 245.1 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase TPR_2 PF07719.17 KXS95175.1 - 1.3e-38 128.0 23.2 4.2e-05 23.3 0.0 11.4 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_1 PF00515.28 KXS95175.1 - 8e-36 120.4 13.9 1.4e-06 27.8 0.0 10.4 11 0 0 11 11 11 6 Tetratricopeptide repeat ANAPC3 PF12895.7 KXS95175.1 - 9.2e-33 112.3 13.4 8e-24 83.7 0.2 5.0 4 1 2 6 6 5 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KXS95175.1 - 1.4e-24 84.2 12.7 0.019 15.1 0.0 10.0 11 0 0 11 11 9 5 Tetratricopeptide repeat TPR_14 PF13428.6 KXS95175.1 - 2.2e-21 74.7 24.6 0.0023 18.6 0.2 10.5 7 2 5 12 12 11 6 Tetratricopeptide repeat TPR_11 PF13414.6 KXS95175.1 - 5.4e-21 74.0 4.6 0.00095 18.8 0.0 9.0 5 2 4 9 9 9 5 TPR repeat TPR_12 PF13424.6 KXS95175.1 - 1.2e-20 73.5 21.8 0.00063 20.0 0.7 8.8 6 3 1 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.6 KXS95175.1 - 6.1e-20 71.6 22.7 5.2e-06 27.0 0.2 8.1 6 2 4 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.6 KXS95175.1 - 1.1e-19 70.7 25.3 2e-08 34.6 1.2 8.1 7 2 2 9 9 8 5 Tetratricopeptide repeat TPR_7 PF13176.6 KXS95175.1 - 1.3e-12 46.8 15.2 0.19 11.8 0.0 10.2 10 1 0 10 10 9 4 Tetratricopeptide repeat TPR_17 PF13431.6 KXS95175.1 - 1.9e-09 37.2 9.4 9.1 6.9 0.1 8.4 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXS95175.1 - 2.7e-08 33.9 19.7 0.15 12.8 0.1 9.2 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_9 PF13371.6 KXS95175.1 - 3.2e-08 33.6 11.4 0.00047 20.2 0.7 5.5 5 2 2 7 7 6 2 Tetratricopeptide repeat TPR_3 PF07720.12 KXS95175.1 - 0.00081 19.3 9.6 0.035 14.1 0.0 5.0 5 0 0 5 5 4 1 Tetratricopeptide repeat SNAP PF14938.6 KXS95175.1 - 0.0047 16.4 4.4 1.9 7.9 0.3 3.9 2 2 2 4 4 4 2 Soluble NSF attachment protein, SNAP FAT PF02259.23 KXS95175.1 - 0.0092 15.2 0.1 1 8.5 0.0 2.7 1 1 2 3 3 3 1 FAT domain MIT PF04212.18 KXS95175.1 - 0.015 15.4 2.7 11 6.2 0.0 4.8 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain TPR_15 PF13429.6 KXS95175.1 - 0.023 13.9 13.4 0.045 13.0 2.3 4.3 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.6 KXS95175.1 - 0.026 14.8 1.7 1 9.7 0.3 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 KXS95175.1 - 0.07 13.8 2.0 3.6e+02 2.3 0.0 5.8 6 0 0 6 6 5 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 KXS95175.1 - 0.1 12.2 0.2 4.5 6.9 0.2 3.1 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_21 PF09976.9 KXS95175.1 - 0.18 11.5 7.9 0.049 13.3 2.9 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 KXS95175.1 - 4.7 7.2 16.7 5.2 7.1 0.1 6.7 8 0 0 8 8 8 0 Tetratricopeptide repeat Sugar_tr PF00083.24 KXS95176.1 - 3.9e-89 299.6 21.8 4.6e-89 299.4 21.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS95176.1 - 1.3e-13 50.6 26.6 1.3e-13 50.6 22.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEM125 PF15109.6 KXS95176.1 - 6.1 7.2 7.1 3.4 8.0 0.4 3.3 4 1 1 5 5 5 0 TMEM125 protein family Amino_oxidase PF01593.24 KXS95180.1 - 1.6e-42 146.4 0.1 2.6e-42 145.6 0.1 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXS95180.1 - 9.3e-07 29.0 0.0 3.2e-06 27.3 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KXS95180.1 - 0.021 14.1 0.2 0.048 12.9 0.2 1.6 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 KXS95180.1 - 0.025 13.8 0.0 0.17 11.1 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase F-box PF00646.33 KXS95181.1 - 5.2e-05 23.0 0.0 0.00033 20.4 0.0 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KXS95181.1 - 0.00044 20.1 1.7 0.00096 19.0 0.3 2.3 2 0 0 2 2 2 1 F-box-like CorA PF01544.18 KXS95182.1 - 1.3e-10 41.0 0.2 4.4e-10 39.3 0.0 2.0 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Glyco_hydr_30_2 PF14587.6 KXS95182.1 - 0.07 12.7 0.2 0.11 12.1 0.2 1.2 1 0 0 1 1 1 0 O-Glycosyl hydrolase family 30 Myb_CC_LHEQLE PF14379.6 KXS95182.1 - 0.12 12.1 0.3 0.3 10.8 0.3 1.7 1 0 0 1 1 1 0 MYB-CC type transfactor, LHEQLE motif VMA21 PF09446.10 KXS95182.1 - 0.21 11.7 3.6 0.41 10.8 3.6 1.4 1 0 0 1 1 1 0 VMA21-like domain CorA PF01544.18 KXS95183.1 - 1.4e-10 41.0 0.2 4.6e-10 39.3 0.0 2.0 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Glyco_hydr_30_2 PF14587.6 KXS95183.1 - 0.072 12.7 0.2 0.11 12.0 0.2 1.2 1 0 0 1 1 1 0 O-Glycosyl hydrolase family 30 Myb_CC_LHEQLE PF14379.6 KXS95183.1 - 0.12 12.1 0.3 0.31 10.8 0.3 1.7 1 0 0 1 1 1 0 MYB-CC type transfactor, LHEQLE motif VMA21 PF09446.10 KXS95183.1 - 0.22 11.7 3.6 0.42 10.7 3.6 1.4 1 0 0 1 1 1 0 VMA21-like domain GST_C_3 PF14497.6 KXS95184.1 - 2.5e-07 30.8 0.0 5.3e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXS95184.1 - 2.5e-06 27.6 0.0 6.7e-06 26.2 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KXS95184.1 - 5.7e-06 26.6 0.0 1.1e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXS95184.1 - 6.1e-06 26.4 0.0 2e-05 24.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXS95184.1 - 0.00019 21.4 0.0 0.00034 20.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KXS95184.1 - 0.00021 21.6 0.0 0.00038 20.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXS95185.1 - 2.5e-07 30.8 0.0 5.3e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXS95185.1 - 2.5e-06 27.6 0.0 6.5e-06 26.3 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KXS95185.1 - 5.6e-06 26.6 0.0 1.1e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXS95185.1 - 5.9e-06 26.5 0.0 1.9e-05 24.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXS95185.1 - 0.00018 21.4 0.0 0.00033 20.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KXS95185.1 - 0.0002 21.7 0.0 0.00037 20.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain SAM_2 PF07647.17 KXS95186.1 - 4.6e-07 29.9 0.2 1.1e-06 28.7 0.2 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KXS95186.1 - 0.00017 22.0 1.3 0.00022 21.6 0.3 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PH PF00169.29 KXS95186.1 - 0.0038 17.7 0.2 0.012 16.1 0.2 1.9 1 1 0 1 1 1 1 PH domain SAM_PNT PF02198.16 KXS95186.1 - 0.0039 17.1 0.1 0.0092 15.9 0.1 1.6 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_3 PF18016.1 KXS95186.1 - 0.069 13.0 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) YqhR PF11085.8 KXS95187.1 - 0.029 14.3 0.0 0.029 14.3 0.0 1.1 1 0 0 1 1 1 0 Conserved membrane protein YqhR Taxilin PF09728.9 KXS95188.1 - 6e-84 281.8 62.4 6e-84 281.8 62.4 1.4 2 0 0 2 2 2 1 Myosin-like coiled-coil protein Response_reg PF00072.24 KXS95189.1 - 2e-21 76.2 0.3 2e-21 76.2 0.3 2.0 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 KXS95189.1 - 1.3e-20 73.9 0.0 3e-20 72.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KXS95189.1 - 1.5e-05 24.9 0.0 3.8e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 KXS95189.1 - 0.0043 17.0 0.0 0.012 15.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain WBS_methylT PF12589.8 KXS95190.1 - 3.2e-14 53.4 6.5 6.2e-14 52.5 6.5 1.5 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 KXS95190.1 - 2e-11 44.4 0.0 5.4e-11 43.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS95190.1 - 2.1e-10 41.1 0.0 6.5e-10 39.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS95190.1 - 2.1e-05 25.2 0.0 8.4e-05 23.3 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 KXS95190.1 - 5e-05 23.2 0.0 0.0001 22.1 0.0 1.6 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KXS95190.1 - 0.00042 20.1 0.0 0.00067 19.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KXS95190.1 - 0.0071 15.7 0.0 0.026 13.8 0.0 1.8 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KXS95190.1 - 0.02 14.7 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 KXS95190.1 - 0.022 14.7 0.1 0.15 12.1 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 KXS95190.1 - 0.16 11.5 1.1 7.7 6.0 0.1 2.3 1 1 1 2 2 2 0 Methyltransferase small domain Trehalase PF01204.18 KXS95191.1 - 2.3e-148 495.3 0.1 2.8e-148 494.9 0.1 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 KXS95191.1 - 1.7e-11 43.6 0.0 3.1e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Trehalase PF01204.18 KXS95192.1 - 2e-148 495.4 0.1 2.4e-148 495.2 0.1 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 KXS95192.1 - 1.6e-11 43.7 0.0 3e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Ank_2 PF12796.7 KXS95193.1 - 2.8e-32 111.2 0.1 2e-07 31.5 0.0 5.3 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS95193.1 - 3.8e-21 72.9 11.9 0.00017 21.7 0.0 10.1 10 0 0 10 10 10 6 Ankyrin repeat Ank_4 PF13637.6 KXS95193.1 - 1.1e-17 64.1 4.7 1.2e-07 32.1 0.0 7.5 4 4 7 11 11 11 5 Ankyrin repeats (many copies) Ank PF00023.30 KXS95193.1 - 6.4e-17 61.2 17.3 0.00073 19.9 0.0 9.0 9 0 0 9 9 9 4 Ankyrin repeat Ank_5 PF13857.6 KXS95193.1 - 1.5e-16 60.2 3.8 3.1e-05 24.2 0.1 7.8 6 3 3 9 9 9 4 Ankyrin repeats (many copies) Fungal_trans_2 PF11951.8 KXS95194.1 - 3.8e-80 269.6 0.1 5.2e-80 269.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS95194.1 - 5.8e-06 26.3 9.1 1.2e-05 25.3 9.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TRM PF02005.16 KXS95194.1 - 0.16 11.1 0.6 0.79 8.8 1.0 1.8 2 0 0 2 2 2 0 N2,N2-dimethylguanosine tRNA methyltransferase HTH_37 PF13744.6 KXS95194.1 - 0.54 10.2 4.8 1.5 8.8 4.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain FmiP_Thoc5 PF09766.9 KXS95195.1 - 6.3e-25 88.2 5.3 8.6e-25 87.8 5.3 1.2 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 K-box PF01486.17 KXS95195.1 - 0.023 14.9 0.4 0.023 14.9 0.4 2.7 3 1 0 3 3 3 0 K-box region Fungal_TACC PF12709.7 KXS95195.1 - 0.13 12.7 2.7 14 6.2 0.5 2.7 2 1 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins APG6_N PF17675.1 KXS95195.1 - 1.5 9.3 17.0 0.23 12.0 2.8 2.3 2 1 0 2 2 2 0 Apg6 coiled-coil region M16C_assoc PF08367.11 KXS95196.1 - 2e-80 269.6 0.1 3.3e-80 268.9 0.1 1.4 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 KXS95196.1 - 8.4e-26 91.1 0.2 8.3e-18 65.0 0.1 2.9 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KXS95196.1 - 3.6e-09 36.8 0.1 1.4e-07 31.6 0.0 3.1 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Erv26 PF04148.13 KXS95197.1 - 3.4e-92 307.9 0.2 4.2e-92 307.6 0.2 1.1 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 Sugar_tr PF00083.24 KXS95198.1 - 7.4e-05 21.8 0.5 9.2e-05 21.5 0.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Lectin_leg-like PF03388.13 KXS95200.1 - 2e-28 99.3 0.0 2.9e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family Nup54 PF13874.6 KXS95200.1 - 0.068 13.3 2.5 0.51 10.4 1.4 2.2 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Baculo_PEP_C PF04513.12 KXS95200.1 - 0.16 12.0 1.3 17 5.5 0.0 2.8 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus AA_permease_2 PF13520.6 KXS95201.1 - 4.5e-42 144.4 56.2 5.9e-42 144.0 56.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXS95201.1 - 4.4e-18 65.1 47.5 6.1e-18 64.7 47.5 1.1 1 0 0 1 1 1 1 Amino acid permease p450 PF00067.22 KXS95203.1 - 1.4e-40 139.4 0.0 1.9e-40 139.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1192 PF06698.11 KXS95203.1 - 0.13 12.4 0.1 0.29 11.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) IATP PF04568.12 KXS95206.1 - 4.3e-13 49.5 0.0 5.1e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Band_7 PF01145.25 KXS95207.1 - 1.1e-20 74.4 4.1 2e-20 73.5 4.1 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family Med10 PF09748.9 KXS95208.1 - 0.013 15.4 0.0 0.037 14.0 0.0 1.6 2 0 0 2 2 2 0 Transcription factor subunit Med10 of Mediator complex Kelch_5 PF13854.6 KXS95209.1 - 1.8e-18 66.1 5.5 9.2e-09 35.1 0.0 5.0 4 0 0 4 4 4 4 Kelch motif Kelch_3 PF13415.6 KXS95209.1 - 5.7e-10 39.2 11.0 0.39 11.0 0.1 6.1 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 KXS95209.1 - 2.4e-08 34.0 11.3 0.11 12.9 0.0 5.6 4 1 1 5 5 5 4 Kelch motif Kelch_4 PF13418.6 KXS95209.1 - 4.5e-05 23.4 10.9 1.5 8.9 0.0 6.0 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.25 KXS95209.1 - 0.00055 19.5 9.1 0.03 13.9 0.9 4.9 5 0 0 5 5 5 1 Kelch motif Kelch_2 PF07646.15 KXS95209.1 - 0.0016 18.3 1.3 0.051 13.6 0.2 3.9 4 0 0 4 4 4 1 Kelch motif Herpes_gE PF02480.16 KXS95209.1 - 0.03 13.1 0.0 0.048 12.4 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E RA PF00788.23 KXS95210.1 - 0.075 13.7 0.0 0.21 12.2 0.0 1.7 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain DUF4558 PF15104.6 KXS95210.1 - 2 8.5 6.1 3.2 7.9 5.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4558) Acetyltransf_10 PF13673.7 KXS95211.1 - 7.1e-11 42.1 0.0 1e-10 41.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXS95211.1 - 2.2e-09 37.6 0.1 3.2e-09 37.0 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXS95211.1 - 4.8e-08 33.3 0.0 7.6e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXS95211.1 - 0.0012 19.0 0.0 0.039 14.0 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXS95211.1 - 0.0014 18.6 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KXS95211.1 - 0.0042 17.2 0.0 0.0088 16.2 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 KXS95211.1 - 0.07 13.8 0.0 0.21 12.2 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DEAD PF00270.29 KXS95212.1 - 1.9e-38 132.0 0.0 3.1e-38 131.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXS95212.1 - 1.1e-21 77.2 0.0 1.2e-20 73.9 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXS95212.1 - 3.5e-05 23.9 0.0 7.6e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KXS95212.1 - 0.033 14.5 0.0 0.11 12.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KXS95212.1 - 0.079 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain VTC PF09359.10 KXS95213.1 - 3.7e-99 331.6 0.2 3.7e-99 331.6 0.2 2.1 2 0 0 2 2 2 1 VTC domain DUF202 PF02656.15 KXS95213.1 - 9.8e-12 45.2 5.9 1.9e-11 44.2 5.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) SPX PF03105.19 KXS95213.1 - 5.4e-11 43.0 22.8 1.3e-05 25.3 0.1 3.9 3 1 1 4 4 4 3 SPX domain VTC PF09359.10 KXS95214.1 - 3.3e-99 331.8 0.2 3.3e-99 331.8 0.2 2.1 2 0 0 2 2 2 1 VTC domain DUF202 PF02656.15 KXS95214.1 - 8.7e-12 45.3 5.9 1.7e-11 44.4 5.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) SPX PF03105.19 KXS95214.1 - 3.1e-11 43.8 22.5 1.2e-05 25.4 0.1 4.0 3 1 1 4 4 4 3 SPX domain zf-TRM13_CCCH PF11722.8 KXS95214.1 - 0.12 12.1 6.5 0.05 13.4 2.7 2.5 2 0 0 2 2 2 0 CCCH zinc finger in TRM13 protein RCR PF12273.8 KXS95215.1 - 1.5e-11 45.0 0.1 1.9e-11 44.6 0.1 1.1 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Rhabdo_glycop PF00974.18 KXS95215.1 - 0.11 10.9 0.5 0.15 10.5 0.5 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein DUF4083 PF13314.6 KXS95215.1 - 0.21 11.5 0.1 0.26 11.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) PepSY_TM PF03929.16 KXS95215.1 - 4.5 6.9 8.0 4.9 6.7 7.0 1.6 1 1 1 2 2 2 0 PepSY-associated TM region Acetyltransf_7 PF13508.7 KXS95216.1 - 3.6e-05 24.1 0.0 7.3e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXS95216.1 - 0.00011 22.2 0.0 0.00018 21.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXS95216.1 - 0.0094 16.2 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family CVNH PF08881.10 KXS95217.1 - 3.7e-26 91.8 1.4 7.5e-26 90.8 1.4 1.6 1 0 0 1 1 1 1 CVNH domain Rick_17kDa_Anti PF05433.15 KXS95217.1 - 2.9e-05 23.8 10.6 2.9e-05 23.8 10.6 2.2 3 0 0 3 3 3 1 Glycine zipper 2TM domain SR-25 PF10500.9 KXS95217.1 - 0.0017 18.0 18.4 0.0026 17.4 18.4 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Gly-zipper_Omp PF13488.6 KXS95217.1 - 0.0022 17.9 3.7 0.0022 17.9 3.7 2.3 3 0 0 3 3 3 1 Glycine zipper DUF863 PF05904.11 KXS95217.1 - 0.0027 16.2 0.0 0.0041 15.6 0.0 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF863) IMUP PF15761.5 KXS95217.1 - 0.0034 18.1 13.6 0.014 16.1 13.6 2.1 1 0 0 1 1 1 1 Immortalisation up-regulated protein DUF533 PF04391.12 KXS95217.1 - 0.038 13.6 0.6 0.083 12.5 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF533) RAP1 PF07218.11 KXS95217.1 - 1.6 6.9 7.8 2.5 6.3 7.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF755 PF05501.11 KXS95217.1 - 1.7 8.9 21.8 4.3 7.6 21.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF755) TFIIF_alpha PF05793.12 KXS95217.1 - 2.2 6.8 10.1 3.2 6.2 10.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CCDC106 PF15794.5 KXS95217.1 - 9.3 5.9 8.3 15 5.2 8.3 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 FAD_binding_3 PF01494.19 KXS95218.1 - 4.1e-09 36.2 0.1 1e-08 34.9 0.1 1.6 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 KXS95218.1 - 0.0024 17.2 0.0 0.0051 16.1 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 KXS95218.1 - 0.0061 15.7 0.3 2.3 7.2 0.0 2.6 3 0 0 3 3 3 2 Lycopene cyclase protein SE PF08491.10 KXS95218.1 - 0.014 14.4 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase Pyr_redox_2 PF07992.14 KXS95218.1 - 0.024 13.9 0.1 3.1 7.0 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_47 PF01532.20 KXS95219.1 - 1.8e-181 604.0 0.0 2.4e-181 603.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF4400 PF14348.6 KXS95219.1 - 0.16 11.4 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) Yae1_N PF09811.9 KXS95222.1 - 0.0015 18.2 4.6 0.0095 15.6 4.6 2.1 1 1 0 1 1 1 1 Essential protein Yae1, N terminal MFS_1 PF07690.16 KXS95223.1 - 1.3e-37 129.6 32.5 1.3e-37 129.6 32.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Halo_GVPC PF05465.13 KXS95224.1 - 0.23 11.7 3.0 0.45 10.8 3.0 1.5 1 0 0 1 1 1 0 Halobacterial gas vesicle protein C (GVPC) repeat MFS_1 PF07690.16 KXS95225.1 - 3.2e-38 131.6 27.3 7.8e-37 127.0 28.8 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2530 PF10745.9 KXS95225.1 - 0.053 13.8 0.2 0.053 13.8 0.2 4.3 4 1 1 5 5 5 0 Protein of unknown function (DUF2530) BTP PF05232.12 KXS95225.1 - 0.36 10.9 4.3 0.63 10.1 0.1 3.3 3 0 0 3 3 3 0 Chlorhexidine efflux transporter DUF373 PF04123.13 KXS95225.1 - 6.7 6.0 7.2 0.5 9.8 0.3 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF373) Halo_GVPC PF05465.13 KXS95226.1 - 0.23 11.7 3.0 0.45 10.8 3.0 1.5 1 0 0 1 1 1 0 Halobacterial gas vesicle protein C (GVPC) repeat F-box-like PF12937.7 KXS95227.1 - 0.00059 19.7 0.9 0.14 12.1 0.1 3.7 3 0 0 3 3 3 1 F-box-like AAA_11 PF13086.6 KXS95229.1 - 0.012 15.4 0.9 0.017 14.9 0.9 1.2 1 0 0 1 1 1 0 AAA domain RAP1 PF07218.11 KXS95229.1 - 0.14 10.4 0.4 0.16 10.3 0.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF5401 PF17380.2 KXS95229.1 - 0.49 8.4 8.4 0.62 8.1 8.4 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Med19 PF10278.9 KXS95229.1 - 1.4 8.8 8.6 1.8 8.4 8.6 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 RIC3 PF15361.6 KXS95229.1 - 2.8 8.3 6.1 4.3 7.7 6.1 1.2 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Cupin_2 PF07883.11 KXS95231.1 - 5.9e-10 38.7 0.2 9.2e-10 38.1 0.2 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KXS95231.1 - 0.0027 17.3 0.0 0.0036 16.9 0.0 1.2 1 0 0 1 1 1 1 Cupin Auxin_BP PF02041.16 KXS95231.1 - 0.016 14.9 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 Auxin binding protein MannoseP_isomer PF01050.18 KXS95231.1 - 0.039 13.8 0.0 0.049 13.5 0.0 1.1 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase DUF386 PF04074.12 KXS95231.1 - 0.048 13.6 0.0 0.081 12.8 0.0 1.3 1 0 0 1 1 1 0 YhcH/YjgK/YiaL CDO_I PF05995.12 KXS95231.1 - 0.072 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Cysteine dioxygenase type I SET PF00856.28 KXS95232.1 - 2.6e-09 37.7 0.0 7.3e-09 36.2 0.0 1.8 1 1 0 1 1 1 1 SET domain p450 PF00067.22 KXS95233.1 - 3.6e-39 134.8 0.0 1.2e-37 129.7 0.0 2.6 1 1 0 1 1 1 1 Cytochrome P450 NARP1 PF12569.8 KXS95234.1 - 0.18 10.7 0.0 0.24 10.2 0.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 GMC_oxred_N PF00732.19 KXS95235.1 - 1e-56 192.5 0.0 1.4e-56 192.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXS95235.1 - 9.5e-27 94.3 0.0 1.6e-26 93.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.6 KXS95235.1 - 0.00046 19.5 0.0 0.17 11.1 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXS95235.1 - 0.00081 19.1 1.8 0.0063 16.1 1.8 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXS95235.1 - 0.00083 18.5 0.2 0.01 14.9 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 KXS95235.1 - 0.006 15.7 0.0 0.0098 15.0 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KXS95235.1 - 0.007 15.6 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KXS95235.1 - 0.02 15.1 0.0 0.051 13.8 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 KXS95235.1 - 0.023 14.9 0.1 0.061 13.6 0.1 1.7 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_2 PF07992.14 KXS95235.1 - 0.04 13.1 0.0 0.069 12.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RTC PF01137.21 KXS95246.1 - 6.9e-65 218.4 0.0 8.3e-65 218.1 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase DUF4444 PF14563.6 KXS95246.1 - 0.075 12.7 1.0 0.13 11.9 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4444) DUF1648 PF07853.11 KXS95246.1 - 0.18 11.5 2.0 0.31 10.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1648) Thioredoxin PF00085.20 KXS95247.1 - 5.6e-24 84.1 0.0 8.4e-24 83.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KXS95247.1 - 1.8e-05 25.1 0.1 6.5e-05 23.3 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 KXS95247.1 - 0.0003 20.2 0.0 0.00037 19.9 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 KXS95247.1 - 0.00033 20.9 0.1 0.0054 17.0 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_7 PF13899.6 KXS95247.1 - 0.0005 20.2 0.0 0.00081 19.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 KXS95247.1 - 0.0029 17.4 0.0 0.0071 16.1 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin AhpC-TSA PF00578.21 KXS95247.1 - 0.026 14.4 0.1 0.06 13.3 0.1 1.6 1 1 1 2 2 2 0 AhpC/TSA family SelK_SelG PF10961.8 KXS95247.1 - 0.22 12.2 2.1 22 5.8 0.0 2.3 2 0 0 2 2 2 0 Selenoprotein SelK_SelG p450 PF00067.22 KXS95248.1 - 2.8e-63 214.3 0.0 3.3e-63 214.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Asparaginase PF00710.20 KXS95249.1 - 6e-52 176.0 0.0 9.1e-52 175.4 0.0 1.3 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KXS95249.1 - 2.6e-27 95.3 0.1 4.4e-27 94.6 0.1 1.3 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Aa_trans PF01490.18 KXS95250.1 - 1.8e-77 260.8 22.3 2.2e-77 260.5 22.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein IMP2_C PF18591.1 KXS95250.1 - 0.14 12.0 0.0 15 5.5 0.0 2.7 2 0 0 2 2 2 0 Immune Mapped Protein 2 (IMP2) C-terminal domain CAAD PF14159.6 KXS95250.1 - 0.46 10.3 2.8 1.2 9.0 0.4 2.9 2 0 0 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Metallophos PF00149.28 KXS95251.1 - 6.8e-11 43.1 1.5 1.4e-10 42.1 1.5 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.18 KXS95251.1 - 0.016 15.5 0.0 0.032 14.4 0.0 1.5 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain Chromo PF00385.24 KXS95252.1 - 3.1e-11 43.0 1.1 0.00017 21.4 0.1 2.5 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Use1 PF09753.9 KXS95252.1 - 1.4 8.6 0.0 1.4 8.6 0.0 3.9 4 1 1 5 5 5 0 Membrane fusion protein Use1 DUF3176 PF11374.8 KXS95253.1 - 2.5e-16 59.8 0.5 1.4e-15 57.4 0.7 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) DUF5516 PF17637.2 KXS95253.1 - 0.62 9.9 3.4 2.1 8.2 3.4 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5516) EF-hand_1 PF00036.32 KXS95255.1 - 1.1e-41 137.3 12.9 7.8e-10 37.6 0.9 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KXS95255.1 - 3.5e-36 123.5 5.8 3.9e-19 68.9 2.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KXS95255.1 - 6.8e-35 118.7 11.4 2.3e-15 56.1 0.6 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 KXS95255.1 - 2.1e-30 102.0 9.5 1.9e-09 36.7 0.2 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KXS95255.1 - 6.5e-26 88.6 10.6 2.6e-06 26.7 0.3 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KXS95255.1 - 1.5e-16 60.5 0.4 2.3e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KXS95255.1 - 3.4e-09 36.6 1.9 0.00075 19.4 0.2 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KXS95255.1 - 5.6e-09 36.3 0.2 0.0016 18.7 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 KXS95255.1 - 9.9e-07 28.7 0.0 0.0077 16.2 0.0 3.0 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 KXS95255.1 - 5.8e-06 26.3 1.6 2.3e-05 24.4 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_11 PF08976.11 KXS95255.1 - 9.1e-05 23.3 0.2 0.0022 18.8 0.1 2.0 1 1 1 2 2 2 1 EF-hand domain TerB PF05099.13 KXS95255.1 - 0.00012 22.0 0.3 0.35 10.8 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.13 KXS95255.1 - 0.00045 20.2 1.8 0.44 10.5 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 KXS95255.1 - 0.00062 20.1 0.8 0.66 10.3 0.1 2.7 2 1 1 3 3 3 2 RNA polymerase Rpb4 DUF3349 PF11829.8 KXS95255.1 - 0.0014 19.3 0.4 3.7 8.4 0.0 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Dockerin_1 PF00404.18 KXS95255.1 - 0.0053 16.9 7.0 0.38 11.0 0.8 2.9 1 1 2 3 3 3 2 Dockerin type I domain DUF5580 PF17743.1 KXS95255.1 - 0.006 15.2 0.0 0.0062 15.1 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) SurA_N_2 PF13623.6 KXS95255.1 - 0.0091 15.9 0.9 0.32 10.9 0.1 2.2 1 1 1 2 2 2 1 SurA N-terminal domain EF-hand_14 PF17959.1 KXS95255.1 - 0.012 16.0 0.5 6.2 7.2 0.1 2.4 1 1 1 2 2 2 0 EF-hand domain Poly_export PF02563.16 KXS95255.1 - 0.023 14.9 0.0 0.18 12.1 0.0 2.5 2 1 0 2 2 2 0 Polysaccharide biosynthesis/export protein DUF4497 PF14924.6 KXS95255.1 - 0.036 14.5 0.0 8.7 6.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) RuvA_C PF07499.13 KXS95255.1 - 0.058 13.9 0.1 8.5 6.9 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain MotA_activ PF09114.10 KXS95255.1 - 0.061 13.4 0.3 1.2 9.3 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain dCache_2 PF08269.11 KXS95255.1 - 0.066 12.4 0.1 1.1 8.4 0.1 2.1 1 1 1 2 2 2 0 Cache domain DUF5132 PF17195.4 KXS95255.1 - 0.15 12.2 0.5 21 5.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) RloB PF13707.6 KXS95255.1 - 0.16 12.2 1.1 0.76 9.9 0.2 2.0 1 1 1 2 2 2 0 RloB-like protein RecO_N PF11967.8 KXS95257.1 - 0.054 13.5 0.3 0.12 12.3 0.2 1.6 1 1 0 1 1 1 0 Recombination protein O N terminal MitMem_reg PF13012.6 KXS95258.1 - 1.4e-15 57.7 0.3 5.2e-14 52.6 0.2 2.2 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KXS95258.1 - 0.0005 20.0 0.0 0.00093 19.2 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Exo70 PF03081.15 KXS95258.1 - 0.1 11.7 0.1 0.15 11.1 0.1 1.2 1 0 0 1 1 1 0 Exo70 exocyst complex subunit IMS PF00817.20 KXS95259.1 - 1.6e-40 138.6 0.0 3.3e-40 137.5 0.0 1.6 2 0 0 2 2 2 1 impB/mucB/samB family zf_UBZ PF18439.1 KXS95259.1 - 1.7e-13 49.9 6.9 1.7e-13 49.9 6.9 2.3 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger IMS_C PF11799.8 KXS95259.1 - 8.3e-12 45.8 0.0 4.2e-11 43.6 0.0 2.2 3 0 0 3 3 3 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KXS95259.1 - 0.084 13.2 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 IMS family HHH motif Acetate_kinase PF00871.17 KXS95260.1 - 3.3e-96 322.3 0.1 4.1e-96 322.0 0.1 1.0 1 0 0 1 1 1 1 Acetokinase family SNARE PF05739.19 KXS95261.1 - 2e-16 59.7 0.3 4.9e-16 58.5 0.3 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 KXS95261.1 - 0.00028 20.6 12.9 0.0023 17.6 12.9 2.2 1 1 0 1 1 1 1 Syntaxin DUF3375 PF11855.8 KXS95261.1 - 0.0044 16.0 6.0 0.053 12.4 0.5 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3375) Syntaxin_2 PF14523.6 KXS95261.1 - 0.02 15.3 9.8 0.98 9.8 0.6 2.7 2 1 0 2 2 2 0 Syntaxin-like protein DASH_Dad4 PF08650.10 KXS95261.1 - 0.07 13.1 0.3 0.81 9.7 0.0 2.7 3 0 0 3 3 3 0 DASH complex subunit Dad4 Fusion_gly PF00523.18 KXS95261.1 - 0.072 11.3 1.1 0.1 10.8 1.1 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0 THOC7 PF05615.13 KXS95261.1 - 0.094 13.0 0.1 0.094 13.0 0.1 2.8 2 1 0 2 2 2 0 Tho complex subunit 7 MCPsignal PF00015.21 KXS95261.1 - 0.11 12.3 6.5 0.36 10.6 2.0 2.4 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Rrp15p PF07890.12 KXS95261.1 - 0.15 12.4 4.7 0.11 12.8 2.5 2.0 1 1 1 2 2 2 0 Rrp15p TMPIT PF07851.13 KXS95261.1 - 0.32 10.2 3.7 1.7 7.9 0.2 2.1 2 0 0 2 2 2 0 TMPIT-like protein DUF948 PF06103.11 KXS95261.1 - 0.64 10.3 3.9 55 4.1 0.3 3.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Sec2p PF06428.11 KXS95261.1 - 0.72 9.9 4.3 0.53 10.3 0.4 2.4 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p EF-hand_7 PF13499.6 KXS95262.1 - 3e-19 69.2 2.6 4.6e-13 49.4 0.4 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KXS95262.1 - 6.9e-18 62.8 4.6 8.9e-07 28.0 0.1 3.4 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KXS95262.1 - 1.5e-15 55.7 3.1 2.3e-06 27.1 0.2 3.9 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 KXS95262.1 - 2e-12 46.7 3.7 1.9e-07 30.8 0.1 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KXS95262.1 - 1.3e-06 27.6 5.7 0.053 13.0 0.1 3.5 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 KXS95262.1 - 5.1e-05 23.5 0.0 0.0047 17.2 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 KXS95262.1 - 0.0047 16.9 0.1 0.13 12.2 0.0 2.3 2 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 KXS95262.1 - 0.025 14.5 0.0 8.7 6.2 0.0 2.2 2 0 0 2 2 2 0 Caleosin related protein SPARC_Ca_bdg PF10591.9 KXS95262.1 - 0.025 14.9 2.2 0.67 10.3 1.7 2.1 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Cytomega_UL84 PF06284.11 KXS95262.1 - 0.085 11.3 0.4 0.11 11.0 0.4 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein DUF4834 PF16118.5 KXS95262.1 - 0.13 13.2 4.6 0.23 12.4 4.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF3391 PF11871.8 KXS95262.1 - 0.28 11.7 3.7 0.6 10.6 3.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) DDRGK PF09756.9 KXS95262.1 - 2.3 7.8 13.6 4.5 6.8 11.9 1.9 2 0 0 2 2 2 0 DDRGK domain Casc1_N PF15927.5 KXS95262.1 - 4.9 6.8 13.9 8.5 6.0 13.9 1.3 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus FAD_binding_1 PF00667.20 KXS95263.1 - 5.5e-49 166.7 0.0 7.8e-49 166.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KXS95263.1 - 9.7e-09 35.9 0.0 3.7e-07 30.8 0.0 2.5 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Cupin_2 PF07883.11 KXS95264.1 - 8.8e-12 44.6 0.5 8.8e-12 44.6 0.5 1.5 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 KXS95264.1 - 4.4e-07 29.6 0.0 6.2e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 KXS95264.1 - 0.0017 18.3 0.2 0.0017 18.3 0.2 1.5 2 0 0 2 2 2 1 AraC-like ligand binding domain JmjC PF02373.22 KXS95264.1 - 0.0041 17.5 0.1 0.011 16.1 0.1 1.7 1 1 0 1 1 1 1 JmjC domain, hydroxylase FdtA PF05523.11 KXS95264.1 - 0.022 14.5 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 WxcM-like, C-terminal DMSP_lyase PF16867.5 KXS95264.1 - 0.032 13.9 0.4 0.056 13.1 0.4 1.3 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase Pirin PF02678.16 KXS95264.1 - 0.055 13.4 0.1 0.085 12.8 0.1 1.3 1 0 0 1 1 1 0 Pirin GPI PF06560.11 KXS95264.1 - 0.07 12.4 0.5 0.11 11.7 0.5 1.4 1 1 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) CENP-C_C PF11699.8 KXS95264.1 - 0.22 11.8 0.0 0.31 11.3 0.0 1.2 1 0 0 1 1 1 0 Mif2/CENP-C like zf-rbx1 PF12678.7 KXS95265.1 - 1.7e-09 37.8 2.9 3.3e-09 36.9 2.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KXS95265.1 - 5e-07 29.9 5.6 9.3e-06 25.9 5.6 2.4 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXS95265.1 - 2.1e-05 24.3 3.6 2.5e-05 24.0 0.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS95265.1 - 5.5e-05 23.0 1.2 0.00015 21.6 1.2 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXS95265.1 - 0.00025 20.8 0.8 0.0027 17.5 0.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KXS95265.1 - 0.00039 20.4 0.2 0.00086 19.3 0.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KXS95265.1 - 0.0066 16.3 1.2 0.038 13.9 0.1 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KXS95265.1 - 0.015 15.2 0.6 0.037 14.0 0.6 1.7 1 1 0 1 1 1 0 zinc-RING finger domain zf-P11 PF03854.14 KXS95265.1 - 0.017 14.8 0.9 0.045 13.4 0.1 2.0 2 0 0 2 2 2 0 P-11 zinc finger FANCL_C PF11793.8 KXS95265.1 - 0.2 11.8 2.6 1.3 9.2 2.6 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.6 KXS95265.1 - 0.66 10.1 5.2 0.49 10.5 2.7 2.1 1 1 1 2 2 2 0 RING-type zinc-finger zf-Di19 PF05605.12 KXS95265.1 - 4.1 7.8 7.5 5.9 7.3 0.1 3.5 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding F-box-like PF12937.7 KXS95266.1 - 0.03 14.2 0.2 0.14 12.0 0.2 2.2 1 1 0 1 1 1 0 F-box-like adh_short_C2 PF13561.6 KXS95267.1 - 3.6e-56 190.3 0.1 5.2e-56 189.8 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS95267.1 - 1.5e-40 138.7 0.2 2.3e-40 138.2 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS95267.1 - 1.5e-13 51.1 0.2 2.5e-13 50.3 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS95267.1 - 0.0026 17.3 0.1 0.0053 16.2 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 KXS95267.1 - 0.012 15.6 0.4 0.7 9.9 0.4 2.3 1 1 0 1 1 1 0 Zinc-binding dehydrogenase GDP_Man_Dehyd PF16363.5 KXS95267.1 - 0.028 13.8 0.0 4.3 6.6 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 KXS95267.1 - 0.096 12.6 0.1 0.4 10.5 0.1 2.0 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TMCCDC2 PF15844.5 KXS95268.1 - 0.098 12.6 0.3 0.18 11.7 0.3 1.5 1 0 0 1 1 1 0 Transmembrane and coiled-coil domain-containing protein 2 DUF5392 PF17370.2 KXS95268.1 - 0.38 10.8 1.6 0.54 10.3 0.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5392) Amino_oxidase PF01593.24 KXS95269.1 - 4.7e-61 207.4 0.1 2.5e-60 205.1 0.1 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXS95269.1 - 1.4e-12 47.6 0.1 2.7e-12 46.7 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXS95269.1 - 0.2 10.9 0.1 0.54 9.4 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Adaptin_N PF01602.20 KXS95270.1 - 9e-117 390.8 0.9 1.2e-116 390.4 0.9 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 KXS95270.1 - 9e-58 194.7 0.4 1.8e-57 193.7 0.4 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 KXS95270.1 - 3.3e-33 114.3 0.2 1e-32 112.6 0.1 2.0 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 KXS95270.1 - 1.5e-19 70.2 4.0 2.7e-12 46.9 0.1 5.4 3 1 2 5 5 5 2 HEAT repeats Cnd1 PF12717.7 KXS95270.1 - 1e-10 41.9 8.2 0.0046 17.0 0.1 4.6 4 1 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KXS95270.1 - 0.0023 18.0 10.4 0.47 10.8 0.2 6.3 6 0 0 6 6 6 1 HEAT repeat HEAT_PBS PF03130.16 KXS95270.1 - 0.046 14.4 2.2 13 6.8 0.1 4.7 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat DUF5010 PF16402.5 KXS95270.1 - 0.076 11.8 0.0 0.87 8.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5010) HEAT_EZ PF13513.6 KXS95270.1 - 1.8 9.1 6.3 0.32 11.5 0.7 2.8 3 0 0 3 3 3 0 HEAT-like repeat Phage_TTP_13 PF16463.5 KXS95274.1 - 0.033 13.7 0.2 0.07 12.7 0.1 1.5 1 1 1 2 2 2 0 Phage tail tube protein family DAO PF01266.24 KXS95275.1 - 6.7e-61 206.8 0.0 7.7e-61 206.6 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXS95275.1 - 2.4e-07 30.9 0.2 5.3e-07 29.8 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXS95275.1 - 0.00012 21.5 0.3 0.00023 20.5 0.3 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KXS95275.1 - 0.00043 20.5 0.1 0.0008 19.7 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain ApbA PF02558.16 KXS95275.1 - 0.00062 19.4 0.1 0.0011 18.7 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 KXS95275.1 - 0.003 16.3 0.2 0.0049 15.6 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 KXS95275.1 - 0.0031 16.8 0.0 0.0055 16.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXS95275.1 - 0.0044 16.3 0.0 0.0092 15.2 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KXS95275.1 - 0.0058 15.7 0.1 0.023 13.8 0.2 1.9 2 1 1 3 3 3 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 KXS95275.1 - 0.0066 15.7 0.1 0.011 15.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain 2-Hacid_dh_C PF02826.19 KXS95275.1 - 0.0087 15.4 0.3 0.027 13.8 0.1 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 KXS95275.1 - 0.0095 15.9 0.1 0.029 14.3 0.1 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KXS95275.1 - 0.012 14.7 0.4 0.02 14.0 0.4 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 KXS95275.1 - 0.016 15.8 0.0 0.084 13.4 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 KXS95275.1 - 0.016 15.5 0.9 0.11 12.7 0.3 2.5 2 1 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 KXS95275.1 - 0.15 12.5 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding F420_oxidored PF03807.17 KXS95275.1 - 0.16 12.6 0.4 0.42 11.2 0.1 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent TPP_enzyme_N PF02776.18 KXS95276.1 - 5.8e-38 130.2 0.0 6.1e-37 126.9 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KXS95276.1 - 4.7e-19 68.7 0.0 1.2e-18 67.4 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KXS95276.1 - 9.4e-11 41.6 0.0 1.4e-09 37.8 0.0 2.8 4 0 0 4 4 4 1 Thiamine pyrophosphate enzyme, central domain AA_permease_2 PF13520.6 KXS95277.1 - 5.2e-54 183.7 44.2 7e-54 183.3 44.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXS95277.1 - 4.6e-33 114.5 39.8 6.1e-33 114.1 39.8 1.0 1 0 0 1 1 1 1 Amino acid permease XhlA PF10779.9 KXS95277.1 - 0.09 13.0 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Haemolysin XhlA PEP_mutase PF13714.6 KXS95278.1 - 2.6e-40 138.4 1.5 3.3e-40 138.1 1.5 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 KXS95278.1 - 7.5e-18 64.3 0.3 1.1e-17 63.8 0.3 1.2 1 0 0 1 1 1 1 Isocitrate lyase family S-methyl_trans PF02574.16 KXS95278.1 - 0.055 13.3 0.1 0.082 12.7 0.1 1.3 1 1 0 1 1 1 0 Homocysteine S-methyltransferase DUF3965 PF13112.6 KXS95278.1 - 0.23 10.6 0.0 0.32 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3965) Git3 PF11710.8 KXS95279.1 - 1.8e-15 57.3 21.7 1.4e-13 51.1 16.7 3.0 2 1 0 2 2 2 2 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 KXS95279.1 - 4.4e-06 26.7 0.0 4.4e-06 26.7 0.0 2.3 3 0 0 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 C-term Dicty_CAR PF05462.11 KXS95279.1 - 0.00049 19.3 11.2 0.00064 19.0 11.2 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Aconitase PF00330.20 KXS95280.1 - 8e-76 255.9 0.0 4.9e-74 250.0 0.0 2.2 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KXS95280.1 - 2.4e-11 44.1 0.0 5.6e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain Aconitase_2_N PF06434.13 KXS95280.1 - 0.052 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Aconitate hydratase 2 N-terminus Lactamase_B PF00753.27 KXS95281.1 - 1.7e-09 38.0 4.1 2.2e-09 37.6 4.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXS95281.1 - 0.016 14.8 1.0 0.027 14.0 1.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain BAR_2 PF10455.9 KXS95283.1 - 2.8e-55 187.5 0.2 3.9e-55 187.0 0.2 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking MRJP PF03022.16 KXS95283.1 - 1.5e-20 73.8 0.0 2.5e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 Major royal jelly protein BAR PF03114.18 KXS95283.1 - 2.9e-15 56.6 6.3 3.8e-14 52.9 6.3 2.0 1 1 0 1 1 1 1 BAR domain DUF2564 PF10819.8 KXS95283.1 - 0.54 10.7 6.4 0.31 11.5 2.7 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2564) Phosducin PF02114.16 KXS95284.1 - 4.4e-10 38.9 0.1 6.5e-10 38.4 0.1 1.2 1 0 0 1 1 1 1 Phosducin MFS_1 PF07690.16 KXS95285.1 - 2.9e-37 128.4 28.1 4.1e-37 127.9 28.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily HXXEE PF13787.6 KXS95285.1 - 5.9 7.7 7.9 0.7 10.7 0.2 3.1 3 1 0 3 3 3 0 Protein of unknown function with HXXEE motif CMD PF02627.20 KXS95286.1 - 1.2e-18 66.9 0.1 2.9e-18 65.7 0.0 1.6 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family DUF2827 PF10933.8 KXS95286.1 - 0.05 12.3 0.0 0.068 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2827) PH_4 PF15404.6 KXS95287.1 - 4.2e-63 212.4 0.4 1.1e-62 211.1 0.4 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Spo7_2_N PF15407.6 KXS95287.1 - 7.9e-22 76.7 0.4 7.9e-22 76.7 0.4 2.5 3 0 0 3 3 3 1 Sporulation protein family 7 PH PF00169.29 KXS95287.1 - 1.2e-10 41.9 0.7 0.03 14.8 0.1 5.5 4 1 0 4 4 4 3 PH domain PH_6 PF15406.6 KXS95287.1 - 0.0087 16.3 0.4 0.044 14.1 0.2 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.6 KXS95287.1 - 0.026 14.9 0.1 34 4.8 0.0 3.9 4 0 0 4 4 4 0 Pleckstrin homology domain Serinc PF03348.15 KXS95288.1 - 1.7e-158 528.1 6.8 1.9e-158 527.9 6.8 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) NPR3 PF03666.13 KXS95288.1 - 0.29 9.9 0.3 0.41 9.4 0.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 NOA36 PF06524.12 KXS95288.1 - 9.9 5.4 7.8 0.1 11.9 0.2 1.5 2 0 0 2 2 2 0 NOA36 protein ADH_N PF08240.12 KXS95294.1 - 3.8e-07 30.0 0.1 8.6e-07 28.8 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXS95294.1 - 3.1e-06 27.2 1.1 6.3e-06 26.2 1.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Oxidored_nitro PF00148.19 KXS95294.1 - 0.028 13.2 0.3 0.037 12.8 0.0 1.4 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase FYVE PF01363.21 KXS95297.1 - 2.8e-21 75.4 1.1 2.8e-21 75.4 1.1 2.8 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.6 KXS95297.1 - 4.7e-08 33.2 24.6 2e-06 28.0 4.9 3.4 3 0 0 3 3 3 3 Ring finger domain zf-C3HC4_2 PF13923.6 KXS95297.1 - 6.2e-06 26.0 2.1 6.2e-06 26.0 2.1 3.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS95297.1 - 2.1e-05 24.3 1.5 2.1e-05 24.3 1.5 3.9 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXS95297.1 - 6.3e-05 22.6 12.5 0.00042 20.0 6.5 2.7 2 0 0 2 2 2 1 RING-like zinc finger Rad50_zn_hook PF04423.14 KXS95297.1 - 0.0036 17.1 4.8 0.57 10.1 0.9 2.4 2 0 0 2 2 2 2 Rad50 zinc hook motif Zn-C2H2_12 PF18112.1 KXS95297.1 - 0.013 16.0 1.5 5.4 7.6 0.1 2.7 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-RING_UBOX PF13445.6 KXS95297.1 - 0.017 15.2 2.5 0.017 15.2 2.5 3.8 3 0 0 3 3 3 0 RING-type zinc-finger FYVE_2 PF02318.16 KXS95297.1 - 0.031 14.5 1.8 0.031 14.5 1.8 2.0 2 0 0 2 2 2 0 FYVE-type zinc finger RNF220 PF15926.5 KXS95297.1 - 0.079 12.6 1.0 0.22 11.1 0.0 2.1 2 1 0 2 2 2 0 E3 ubiquitin-protein ligase RNF220 Elf1 PF05129.13 KXS95297.1 - 0.2 11.7 3.1 0.7 10.0 0.9 2.5 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like PEGSRP PF07623.11 KXS95297.1 - 0.2 11.5 4.0 0.16 11.8 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1584) Opy2 PF09463.10 KXS95297.1 - 0.6 10.5 5.9 0.75 10.2 1.3 2.8 2 0 0 2 2 2 0 Opy2 protein DZR PF12773.7 KXS95297.1 - 3.7 7.6 12.6 7.4 6.7 0.1 3.0 3 0 0 3 3 2 0 Double zinc ribbon zf-B_box PF00643.24 KXS95297.1 - 4.9 7.4 12.0 1.1 9.5 6.6 2.6 2 0 0 2 2 2 0 B-box zinc finger HypA PF01155.19 KXS95297.1 - 5.5 7.1 7.0 3.2 7.8 2.4 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Fungal_trans_2 PF11951.8 KXS95298.1 - 2.2e-05 23.5 1.8 0.00016 20.7 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain DUF3405 PF11885.8 KXS95299.1 - 1.2e-198 660.9 17.8 5.7e-181 602.6 11.8 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3405) Phytase-like PF13449.6 KXS95300.1 - 0.039 13.9 0.1 0.04 13.9 0.1 1.0 1 0 0 1 1 1 0 Esterase-like activity of phytase zf-HC5HC2H PF13771.6 KXS95301.1 - 7.5e-05 22.9 0.7 7.5e-05 22.9 0.7 1.7 2 0 0 2 2 2 1 PHD-like zinc-binding domain Prok-RING_1 PF14446.6 KXS95301.1 - 0.00013 21.8 1.8 0.00013 21.8 1.8 3.1 3 0 0 3 3 3 1 Prokaryotic RING finger family 1 zf-RING_2 PF13639.6 KXS95301.1 - 0.00034 20.9 4.6 0.00034 20.9 4.6 2.7 2 1 0 2 2 2 1 Ring finger domain FANCL_C PF11793.8 KXS95301.1 - 0.0014 18.7 1.1 0.0014 18.7 1.1 2.3 2 0 0 2 2 2 1 FANCL C-terminal domain PHD PF00628.29 KXS95301.1 - 0.01 15.7 4.9 0.044 13.7 4.9 2.2 1 1 0 1 1 1 0 PHD-finger Vps39_2 PF10367.9 KXS95301.1 - 0.062 13.8 0.0 0.16 12.5 0.0 1.7 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 Golgin_A5 PF09787.9 KXS95302.1 - 0.0018 17.8 14.8 0.0026 17.3 14.8 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 Fez1 PF06818.15 KXS95302.1 - 0.0024 18.3 12.1 0.0037 17.8 12.1 1.2 1 0 0 1 1 1 1 Fez1 Phage_int_SAM_1 PF02899.17 KXS95302.1 - 0.0047 17.2 3.1 0.21 11.9 0.0 3.2 2 1 0 3 3 3 1 Phage integrase, N-terminal SAM-like domain FPP PF05911.11 KXS95302.1 - 0.0066 14.7 14.5 0.0082 14.4 14.5 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil SlyX PF04102.12 KXS95302.1 - 0.0087 16.7 17.4 0.12 13.1 5.8 3.3 1 1 2 3 3 3 2 SlyX Spc7 PF08317.11 KXS95302.1 - 0.024 13.5 17.1 0.049 12.5 17.0 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein VirB8 PF04335.13 KXS95302.1 - 0.045 13.6 3.9 0.083 12.7 3.9 1.3 1 0 0 1 1 1 0 VirB8 protein PqqD PF05402.12 KXS95302.1 - 0.047 14.0 0.1 20 5.5 0.0 3.3 3 0 0 3 3 3 0 Coenzyme PQQ synthesis protein D (PqqD) 4HBT_3 PF13622.6 KXS95302.1 - 0.067 13.4 0.5 0.11 12.7 0.5 1.4 1 0 0 1 1 1 0 Thioesterase-like superfamily tRNA_int_end_N2 PF12928.7 KXS95302.1 - 0.088 13.0 0.0 0.28 11.4 0.0 1.8 2 0 0 2 2 1 0 tRNA-splicing endonuclease subunit sen54 N-term FAM76 PF16046.5 KXS95302.1 - 0.13 11.6 14.3 0.19 11.1 14.3 1.2 1 0 0 1 1 1 0 FAM76 protein RAP1 PF07218.11 KXS95302.1 - 0.16 10.2 6.1 0.19 9.9 6.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF724 PF05266.14 KXS95302.1 - 0.19 11.6 11.8 0.31 10.8 11.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) V_ATPase_I PF01496.19 KXS95302.1 - 0.2 9.6 6.7 0.25 9.2 6.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atx10homo_assoc PF09759.9 KXS95302.1 - 0.28 11.2 3.0 0.26 11.3 1.3 1.8 1 1 1 2 2 2 0 Spinocerebellar ataxia type 10 protein domain TMF_DNA_bd PF12329.8 KXS95302.1 - 0.43 10.6 22.9 0.74 9.9 16.4 3.0 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF2968 PF11180.8 KXS95302.1 - 0.53 9.9 16.7 0.46 10.1 15.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) ATG16 PF08614.11 KXS95302.1 - 0.58 10.3 26.6 3.6 7.8 25.6 2.1 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.12 KXS95302.1 - 0.87 9.7 22.5 15 5.6 21.7 2.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF3450 PF11932.8 KXS95302.1 - 0.9 8.8 18.7 0.12 11.7 10.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF2570 PF10828.8 KXS95302.1 - 1.3 8.9 10.2 0.87 9.4 7.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) ADIP PF11559.8 KXS95302.1 - 1.8 8.7 21.8 2.7 8.1 20.6 2.0 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF641 PF04859.12 KXS95302.1 - 2.7 8.3 15.1 0.88 9.9 0.6 2.7 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF4407 PF14362.6 KXS95302.1 - 3.9 6.8 16.8 6 6.1 16.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMPIT PF07851.13 KXS95302.1 - 3.9 6.6 7.9 5.4 6.2 7.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein DivIC PF04977.15 KXS95302.1 - 6.1 6.7 21.8 1.2 9.0 1.2 3.4 1 1 2 3 3 3 0 Septum formation initiator UPF0242 PF06785.11 KXS95302.1 - 6.6 6.8 16.8 6.5 6.8 15.9 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF3552 PF12072.8 KXS95303.1 - 0.0076 15.7 8.8 0.0076 15.7 8.8 3.9 1 1 2 3 3 3 2 Domain of unknown function (DUF3552) UPF0242 PF06785.11 KXS95303.1 - 3.6 7.6 32.9 0.27 11.3 22.0 2.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF3285 PF11688.8 KXS95304.1 - 0.2 11.6 0.6 0.42 10.6 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3285) Adipogenin PF15202.6 KXS95305.1 - 7.4 6.7 10.4 0.37 10.9 0.2 2.9 2 1 0 2 2 2 0 Adipogenin PhoLip_ATPase_C PF16212.5 KXS95309.1 - 8.8e-81 271.3 22.7 8.8e-81 271.3 22.7 2.3 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KXS95309.1 - 4e-27 93.7 6.7 1.1e-26 92.2 6.7 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KXS95309.1 - 5.5e-11 42.4 0.0 2.8e-10 40.2 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KXS95309.1 - 1.4e-09 38.6 1.6 2.7e-05 24.6 0.4 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KXS95309.1 - 3e-07 30.2 0.0 1.1e-06 28.3 0.0 2.0 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KXS95309.1 - 0.0047 16.7 0.0 0.024 14.4 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Mt_ATP-synt_B PF05405.14 KXS95309.1 - 0.15 11.7 0.4 0.34 10.5 0.1 1.7 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) ECH_1 PF00378.20 KXS95310.1 - 1.7e-33 116.0 0.1 2.2e-33 115.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXS95310.1 - 9.4e-14 51.6 0.1 1.1e-13 51.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF2099 PF09872.9 KXS95310.1 - 0.17 11.1 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2099) zf-C3HC4_2 PF13923.6 KXS95311.1 - 1.3e-07 31.3 3.5 1.3e-07 31.3 3.5 5.1 5 2 1 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KXS95311.1 - 2.3e-07 30.6 0.3 2.3e-07 30.6 0.3 3.3 3 0 0 3 3 3 1 zf-RING of BARD1-type protein zf-C3HC4 PF00097.25 KXS95311.1 - 2.9e-07 30.2 6.1 2.9e-07 30.2 6.1 5.3 4 3 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXS95311.1 - 5.5e-07 29.5 4.8 5.5e-07 29.5 4.8 4.2 4 1 0 4 4 4 1 RING-type zinc-finger zf-RING_2 PF13639.6 KXS95311.1 - 9.8e-06 25.8 6.9 9.8e-06 25.8 6.9 5.6 5 2 0 5 5 5 1 Ring finger domain zf-RING_5 PF14634.6 KXS95311.1 - 0.00023 21.0 5.7 0.00023 21.0 5.7 5.3 5 1 0 5 5 5 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KXS95311.1 - 0.00045 20.3 6.1 0.00045 20.3 6.1 4.4 6 1 0 6 6 6 1 zinc finger of C3HC4-type, RING SH3_9 PF14604.6 KXS95311.1 - 0.0014 18.4 1.6 0.013 15.3 0.1 2.5 2 0 0 2 2 2 1 Variant SH3 domain ZZ PF00569.17 KXS95311.1 - 0.0017 18.1 6.1 0.0017 18.1 6.1 4.2 4 1 0 4 4 4 1 Zinc finger, ZZ type SH3_1 PF00018.28 KXS95311.1 - 0.0073 15.9 0.0 0.017 14.7 0.0 1.6 1 0 0 1 1 1 1 SH3 domain Rotamase PF00639.21 KXS95312.1 - 2.5e-22 79.6 0.0 3.5e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 KXS95312.1 - 2e-16 60.6 0.0 2.6e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 KXS95312.1 - 5.4e-10 39.2 1.6 5.4e-10 39.2 1.6 1.8 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 KXS95312.1 - 0.00035 21.4 0.0 0.00047 21.0 0.0 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain X8 PF07983.13 KXS95312.1 - 0.036 14.7 0.0 0.078 13.7 0.0 1.5 1 0 0 1 1 1 0 X8 domain MAM PF00629.23 KXS95312.1 - 0.096 12.6 0.0 0.18 11.7 0.0 1.5 1 1 1 2 2 2 0 MAM domain, meprin/A5/mu CTP_synth_N PF06418.14 KXS95313.1 - 1.2e-121 405.0 0.1 1.6e-121 404.6 0.1 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 KXS95313.1 - 3.3e-53 180.3 0.0 4.9e-53 179.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KXS95313.1 - 1e-05 25.4 0.3 9.6e-05 22.2 0.3 2.3 1 1 0 1 1 1 1 Peptidase C26 CbiA PF01656.23 KXS95313.1 - 0.063 13.3 0.0 0.076 13.1 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain EzrA PF06160.12 KXS95314.1 - 0.0025 16.1 0.1 0.003 15.8 0.1 1.0 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA DUF4164 PF13747.6 KXS95314.1 - 0.0068 16.7 0.5 0.64 10.3 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4164) DASH_Spc19 PF08287.11 KXS95314.1 - 0.052 13.4 0.1 0.067 13.1 0.1 1.2 1 0 0 1 1 1 0 Spc19 CdvA PF18822.1 KXS95314.1 - 0.067 13.0 0.1 0.14 12.0 0.0 1.5 2 0 0 2 2 2 0 CdvA-like coiled-coil domain FliD_C PF07195.12 KXS95314.1 - 0.12 11.8 0.1 0.18 11.2 0.1 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus ABC_tran_CTD PF16326.5 KXS95314.1 - 0.13 12.6 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter C-terminal domain Ecl1 PF12855.7 KXS95315.1 - 0.13 13.4 5.8 2.1 9.5 0.0 2.4 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins TFIIS_C PF01096.18 KXS95316.1 - 4.9e-14 51.9 6.5 4.9e-14 51.9 6.5 3.5 4 0 0 4 4 4 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KXS95316.1 - 4.6e-13 48.8 2.5 4.6e-13 48.8 2.5 3.0 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit YecR PF13992.6 KXS95316.1 - 0.0083 16.4 0.7 0.0083 16.4 0.7 1.9 2 0 0 2 2 2 1 YecR-like lipoprotein SET PF00856.28 KXS95317.1 - 4.7e-09 36.8 1.2 1.2e-07 32.3 0.2 3.3 2 1 0 2 2 2 1 SET domain Cu-oxidase_3 PF07732.15 KXS95319.1 - 3.9e-36 123.7 1.9 1.2e-35 122.1 0.1 2.7 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KXS95319.1 - 3e-30 104.7 4.5 3.9e-25 88.2 0.6 3.4 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 KXS95319.1 - 3.8e-17 62.9 0.0 3.3e-16 59.8 0.0 2.5 2 1 0 2 2 2 1 Multicopper oxidase APH PF01636.23 KXS95320.1 - 1.3e-05 25.3 0.0 4.5e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Velvet PF11754.8 KXS95321.1 - 3.2e-45 155.0 0.1 1.9e-29 103.4 0.0 4.4 3 2 1 4 4 4 2 Velvet factor Aldo_ket_red PF00248.21 KXS95322.1 - 1.1e-47 162.7 0.0 1.4e-47 162.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family FOXO_KIX_bdg PF16675.5 KXS95322.1 - 0.0079 16.5 0.1 0.015 15.6 0.1 1.4 1 0 0 1 1 1 1 KIX-binding domain of forkhead box O, CR2 Ribosomal_L11_N PF03946.14 KXS95324.1 - 6.9e-24 83.5 0.1 1.2e-23 82.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 KXS95324.1 - 1.5e-15 57.4 0.4 2.5e-15 56.7 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Cutinase PF01083.22 KXS95325.1 - 5.2e-33 114.5 4.6 7.2e-33 114.0 4.6 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KXS95325.1 - 0.00013 21.6 0.1 0.00021 20.9 0.1 1.3 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_2 PF02230.16 KXS95325.1 - 0.041 13.7 0.4 0.19 11.5 0.0 2.1 2 1 1 3 3 3 0 Phospholipase/Carboxylesterase DUF4413 PF14372.6 KXS95325.1 - 0.19 12.1 0.0 6.4 7.2 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4413) Glyco_hydro_31 PF01055.26 KXS95326.1 - 4.9e-155 517.0 5.2 6.3e-155 516.7 5.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KXS95326.1 - 6.9e-36 123.0 0.0 1.4e-35 122.0 0.0 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KXS95326.1 - 1.1e-12 48.0 0.7 3.6e-12 46.4 0.7 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like U1snRNP70_N PF12220.8 KXS95328.1 - 2e-26 92.4 4.7 3.8e-26 91.5 4.7 1.5 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 KXS95328.1 - 1.1e-15 57.2 0.0 1.8e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXS95328.1 - 0.0042 17.2 0.0 0.0092 16.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif DUF3176 PF11374.8 KXS95330.1 - 1.1e-25 89.8 3.0 1.1e-25 89.8 3.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) Fungal_trans PF04082.18 KXS95330.1 - 1.2e-07 31.1 3.1 2e-07 30.3 3.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Inhibitor_I9 PF05922.16 KXS95333.1 - 9.4e-05 23.0 0.1 0.00011 22.8 0.1 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I9 MctB PF11382.8 KXS95333.1 - 0.053 13.2 0.1 0.053 13.2 0.1 1.0 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB SRP68 PF16969.5 KXS95334.1 - 3.1e-179 597.6 14.3 3.5e-179 597.4 14.3 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 PMEI PF04043.15 KXS95334.1 - 0.02 15.3 6.5 0.34 11.2 2.3 2.7 2 0 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor PfkB PF00294.24 KXS95335.1 - 6.9e-16 58.4 0.1 1.1e-15 57.8 0.1 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase GFA PF04828.14 KXS95336.1 - 3.6e-20 72.1 0.2 5e-20 71.6 0.2 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DUF3797 PF12677.7 KXS95336.1 - 0.47 10.4 7.7 1.3 9.0 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3797) Aldo_ket_red PF00248.21 KXS95337.1 - 2.5e-68 230.4 0.4 2.8e-68 230.3 0.4 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Myb_DNA-binding PF00249.31 KXS95337.1 - 0.076 13.2 0.0 19 5.6 0.0 2.8 2 0 0 2 2 2 0 Myb-like DNA-binding domain Lectin_C PF00059.21 KXS95338.1 - 0.0072 17.1 0.1 0.018 15.8 0.1 1.7 1 0 0 1 1 1 1 Lectin C-type domain Glyco_transf_41 PF13844.6 KXS95339.1 - 1.8e-105 353.1 0.0 8.3e-53 179.5 0.0 3.1 2 1 1 3 3 3 2 Glycosyl transferase family 41 TPR_1 PF00515.28 KXS95339.1 - 4.2e-22 77.0 7.7 6.3e-06 25.8 0.0 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 KXS95339.1 - 3.7e-19 67.2 10.0 0.0011 18.9 0.0 6.6 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 KXS95339.1 - 2e-17 61.9 1.7 0.00036 20.5 0.0 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 KXS95339.1 - 6.8e-14 51.3 15.4 1.1e-05 25.0 0.1 5.3 3 1 2 5 5 5 4 TPR repeat TPR_12 PF13424.6 KXS95339.1 - 1.4e-13 50.9 8.0 2.1e-06 27.9 0.5 5.4 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 KXS95339.1 - 7.8e-13 48.1 3.7 0.041 14.7 0.5 6.5 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 KXS95339.1 - 1.2e-12 47.3 13.1 0.0049 16.7 0.3 6.3 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 KXS95339.1 - 6.8e-12 45.7 9.1 4.8e-06 27.0 0.1 4.1 3 1 0 4 4 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 KXS95339.1 - 1.3e-11 44.0 4.2 0.096 13.1 0.6 5.3 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 KXS95339.1 - 2e-10 39.9 1.6 0.49 10.5 0.0 5.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 KXS95339.1 - 8.4e-09 35.9 6.6 0.0019 18.8 0.2 4.7 3 1 2 5 5 5 3 Tetratricopeptide repeat BTAD PF03704.17 KXS95339.1 - 1.5e-05 25.5 5.1 0.18 12.3 0.0 4.2 5 0 0 5 5 4 2 Bacterial transcriptional activator domain ANAPC3 PF12895.7 KXS95339.1 - 0.00077 19.6 0.2 0.0075 16.5 0.1 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 KXS95339.1 - 0.0012 18.1 1.6 0.1 11.8 0.3 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.14 KXS95339.1 - 0.0027 18.1 5.5 0.0044 17.5 2.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_5 PF12688.7 KXS95339.1 - 0.01 16.1 1.1 0.75 10.1 0.1 2.9 3 0 0 3 3 2 0 Tetratrico peptide repeat TPR_9 PF13371.6 KXS95339.1 - 0.059 13.5 6.3 0.25 11.5 0.3 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXS95339.1 - 0.061 14.0 0.7 2e+02 3.0 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 KXS95339.1 - 0.34 11.0 2.6 1.2e+02 2.9 0.0 4.3 3 1 0 3 3 3 0 MIT (microtubule interacting and transport) domain Sulfate_transp PF00916.20 KXS95340.1 - 2.4e-82 276.7 11.0 8.8e-53 179.4 1.9 2.6 3 0 0 3 3 3 2 Sulfate permease family STAS PF01740.21 KXS95340.1 - 1.7e-16 59.9 0.0 5.2e-16 58.3 0.0 1.8 2 0 0 2 2 2 1 STAS domain MFS_MOT1 PF16983.5 KXS95340.1 - 0.0019 18.6 0.7 0.0019 18.6 0.7 3.0 2 1 0 2 2 2 1 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 KXS95340.1 - 0.05 14.0 0.0 0.16 12.4 0.0 1.8 1 1 0 1 1 1 0 STAS domain DUF4006 PF13179.6 KXS95340.1 - 0.61 10.0 0.0 0.61 10.0 0.0 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF4006) Transgly_assoc PF04226.13 KXS95340.1 - 6.5 7.1 12.4 0.1 12.9 1.7 3.0 2 0 0 2 2 2 0 Transglycosylase associated protein DUF1286 PF06939.11 KXS95340.1 - 7 7.0 8.9 1.3 9.3 0.3 3.2 2 1 2 4 4 4 0 Protein of unknown function (DUF1286) Myb_DNA-binding PF00249.31 KXS95342.1 - 4.1e-23 81.3 1.7 5.9e-13 48.8 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXS95342.1 - 4.9e-17 61.9 1.4 1e-12 48.1 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 KXS95342.1 - 0.0019 18.2 0.0 0.0055 16.7 0.0 1.8 1 0 0 1 1 1 1 SLIDE HTH_23 PF13384.6 KXS95342.1 - 0.094 12.5 0.2 0.2 11.5 0.2 1.5 1 0 0 1 1 1 0 Homeodomain-like domain Dynamin_N PF00350.23 KXS95343.1 - 3.9e-44 150.7 0.0 7.6e-44 149.7 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KXS95343.1 - 3.7e-12 46.1 0.1 9.5e-12 44.7 0.0 1.7 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 KXS95343.1 - 0.00039 20.5 0.0 0.0015 18.6 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.6 KXS95343.1 - 0.011 15.5 0.1 0.17 11.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF4865 PF16157.5 KXS95343.1 - 0.043 13.8 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4865) AAA_16 PF13191.6 KXS95343.1 - 0.048 14.0 3.1 0.15 12.4 0.0 3.1 3 0 0 3 3 3 0 AAA ATPase domain AAA_15 PF13175.6 KXS95343.1 - 0.078 12.7 0.3 0.23 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain adh_short PF00106.25 KXS95344.1 - 1.1e-33 116.3 0.0 1.4e-33 116.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS95344.1 - 8.4e-24 84.4 0.0 1.2e-23 84.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS95344.1 - 1.1e-05 25.4 0.0 9.9e-05 22.3 0.0 2.0 2 0 0 2 2 2 1 KR domain CAP_N PF01213.19 KXS95346.1 - 3.6e-109 365.1 5.1 3.6e-109 365.1 5.1 2.2 2 1 0 2 2 2 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 KXS95346.1 - 4.7e-57 192.0 1.0 6.4e-57 191.6 1.0 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 KXS95346.1 - 0.0035 17.1 2.0 0.17 11.6 1.0 2.3 1 1 1 2 2 2 2 Tubulin binding cofactor C RAP80_UIM PF18282.1 KXS95347.1 - 0.00029 20.5 2.0 0.00029 20.5 2.0 2.3 3 0 0 3 3 3 1 RAP80 N-terminal ubiquitin interaction motif UIM PF02809.20 KXS95347.1 - 0.011 15.7 13.8 0.073 13.0 2.9 2.8 2 0 0 2 2 2 0 Ubiquitin interaction motif zf-RING_2 PF13639.6 KXS95348.1 - 2.5e-13 50.1 17.7 3e-13 49.9 8.1 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 KXS95348.1 - 6.8e-10 38.5 3.5 1.4e-09 37.5 3.5 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KXS95348.1 - 1.6e-09 37.4 7.9 1.6e-09 37.4 7.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXS95348.1 - 8.9e-09 35.1 9.5 1.5e-07 31.2 2.7 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS95348.1 - 1.8e-06 27.7 15.4 4.4e-06 26.5 6.5 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXS95348.1 - 3.8e-06 27.1 7.6 3.8e-06 27.1 7.6 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zinc_ribbon_9 PF14369.6 KXS95348.1 - 6.4e-06 26.3 10.9 0.00024 21.3 5.0 2.6 2 0 0 2 2 2 2 zinc-ribbon zf-RING_5 PF14634.6 KXS95348.1 - 2.3e-05 24.3 5.0 2.3e-05 24.3 5.0 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXS95348.1 - 2.6e-05 24.2 3.0 2.6e-05 24.2 3.0 2.5 2 1 1 3 3 3 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KXS95348.1 - 0.0014 18.4 4.9 0.0014 18.4 4.9 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KXS95348.1 - 0.0054 16.8 2.6 0.0054 16.8 2.6 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger HypA PF01155.19 KXS95348.1 - 0.037 14.0 0.5 0.037 14.0 0.5 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING_4 PF14570.6 KXS95348.1 - 0.065 13.0 13.8 0.098 12.5 4.2 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_1 PF14446.6 KXS95348.1 - 0.13 12.3 12.9 3.9 7.5 1.5 3.3 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-C3HC4_4 PF15227.6 KXS95348.1 - 0.19 11.9 14.1 1.1 9.4 5.1 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Baculo_RING PF05883.11 KXS95348.1 - 0.26 11.3 2.5 0.47 10.4 0.2 2.1 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain DUF1272 PF06906.11 KXS95348.1 - 0.57 10.3 8.1 4.9 7.3 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zinc-ribbons_6 PF07191.12 KXS95348.1 - 2.1 8.4 12.3 0.21 11.6 1.4 2.4 2 1 0 2 2 2 0 zinc-ribbons DZR PF12773.7 KXS95348.1 - 3.6 7.7 11.1 0.79 9.8 0.8 2.5 2 1 0 2 2 2 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 KXS95348.1 - 4.5 7.5 9.6 19 5.5 1.7 3.1 2 1 0 2 2 2 0 Zinc ribbon domain Zn_ribbon_17 PF17120.5 KXS95348.1 - 6.3 6.5 16.6 0.33 10.6 7.5 2.2 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 KXS95348.1 - 8.5 6.4 18.3 2.7 7.9 7.5 2.8 2 1 1 3 3 3 0 PHD-finger MFS_1 PF07690.16 KXS95350.1 - 2.5e-27 95.8 30.4 2.5e-27 95.8 30.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS95352.1 - 3e-72 243.9 25.7 3.5e-72 243.7 25.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS95352.1 - 1.7e-19 70.0 40.3 1.3e-11 44.0 22.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 KXS95353.1 - 5.4e-11 42.0 0.5 2.1e-10 40.1 0.5 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS95353.1 - 0.00059 19.9 1.9 0.0011 19.0 1.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EF-hand_9 PF14658.6 KXS95354.1 - 0.15 12.4 0.3 23 5.4 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain Glycogen_syn PF05693.13 KXS95355.1 - 0 1133.3 0.0 0 1133.1 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 KXS95355.1 - 9e-05 22.1 0.0 0.038 13.5 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KXS95355.1 - 0.00096 19.6 0.0 0.0032 17.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.6 KXS95355.1 - 0.0012 19.2 0.0 0.85 10.1 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KXS95355.1 - 0.0013 18.7 0.2 0.0037 17.3 0.2 1.8 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycogen_syn PF05693.13 KXS95356.1 - 0 1133.7 0.0 0 1133.5 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 KXS95356.1 - 7.4e-05 22.3 0.0 0.034 13.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KXS95356.1 - 0.00085 19.8 0.0 0.0028 18.1 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.6 KXS95356.1 - 0.001 19.5 0.0 0.76 10.2 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KXS95356.1 - 0.0016 18.5 0.2 0.0033 17.5 0.2 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_transf_5 PF08323.11 KXS95356.1 - 0.023 14.4 0.0 0.054 13.2 0.0 1.6 1 0 0 1 1 1 0 Starch synthase catalytic domain Glycogen_syn PF05693.13 KXS95357.1 - 0 1133.6 0.0 0 1133.4 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 KXS95357.1 - 7.8e-05 22.3 0.0 0.035 13.6 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KXS95357.1 - 0.00089 19.7 0.0 0.0029 18.1 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.6 KXS95357.1 - 0.0011 19.5 0.0 0.79 10.2 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KXS95357.1 - 0.0016 18.4 0.2 0.0034 17.4 0.2 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_transf_5 PF08323.11 KXS95357.1 - 0.024 14.3 0.0 0.056 13.1 0.0 1.6 1 0 0 1 1 1 0 Starch synthase catalytic domain MFS_1 PF07690.16 KXS95358.1 - 3.5e-37 128.2 75.3 1.4e-36 126.1 47.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS95358.1 - 0.00012 21.2 39.2 0.017 14.0 39.3 3.2 1 1 0 1 1 1 1 Sugar (and other) transporter DUF4027 PF13219.6 KXS95358.1 - 3.6 7.5 5.4 0.94 9.4 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4027) HrcA_DNA-bdg PF03444.15 KXS95360.1 - 0.13 11.9 0.3 0.21 11.3 0.3 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding AMP-binding PF00501.28 KXS95361.1 - 3.2e-42 144.6 0.0 4.5e-42 144.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KXS95361.1 - 3.5e-05 23.6 0.7 3.5e-05 23.6 0.7 2.1 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KXS95361.1 - 0.062 14.3 0.0 0.13 13.3 0.0 1.5 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain NUDIX_2 PF13869.6 KXS95362.1 - 1.1e-78 263.1 0.0 1.4e-78 262.8 0.0 1.1 1 0 0 1 1 1 1 Nucleotide hydrolase Utp14 PF04615.13 KXS95363.1 - 7.5 5.0 26.7 8.8 4.8 26.7 1.0 1 0 0 1 1 1 0 Utp14 protein Pkinase PF00069.25 KXS95364.1 - 4.1e-68 229.6 0.0 5.7e-68 229.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS95364.1 - 1.6e-46 158.7 0.0 2.2e-46 158.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXS95364.1 - 6.3e-05 21.9 0.0 6.3e-05 21.9 0.0 2.6 3 0 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 KXS95364.1 - 0.0016 17.9 0.0 0.0033 16.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXS95364.1 - 0.0049 16.8 0.0 2.3 8.1 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Peptidase_M22 PF00814.25 KXS95367.1 - 7.5e-86 288.2 0.0 8.9e-86 287.9 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 KXS95367.1 - 0.019 14.7 0.0 0.35 10.5 0.0 2.1 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus Gpr1_Fun34_YaaH PF01184.19 KXS95368.1 - 1.2e-27 96.9 21.1 1.5e-27 96.6 21.1 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Bac_rhamnosid6H PF17389.2 KXS95369.1 - 2.1e-17 63.4 0.5 2e-15 56.9 0.2 2.1 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 KXS95369.1 - 0.00012 21.8 0.0 0.00026 20.7 0.0 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Bac_rhamnosid PF05592.11 KXS95369.1 - 0.0098 15.9 0.0 0.047 13.7 0.0 2.1 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain DUF3759 PF12585.8 KXS95370.1 - 1e-37 128.0 5.4 3.7e-37 126.2 5.4 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3759) DUF3824 PF12868.7 KXS95370.1 - 0.011 16.4 6.7 0.32 11.7 2.0 2.3 2 1 0 2 2 2 0 Domain of unknwon function (DUF3824) B12D PF06522.11 KXS95371.1 - 0.028 14.2 0.0 0.079 12.8 0.0 1.8 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Polyketide_cyc2 PF10604.9 KXS95371.1 - 0.11 12.7 0.2 0.39 11.0 0.2 2.1 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport p450 PF00067.22 KXS95372.1 - 4.3e-54 184.0 0.0 5.5e-54 183.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HH_signal PF01085.18 KXS95373.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Hedgehog amino-terminal signalling domain Abhydrolase_2 PF02230.16 KXS95374.1 - 2.2e-19 70.1 0.0 3e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 KXS95374.1 - 0.0018 18.0 0.0 0.0072 16.0 0.0 1.8 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KXS95374.1 - 0.0042 17.7 0.0 0.005 17.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 KXS95374.1 - 0.019 14.5 0.0 0.037 13.6 0.0 1.4 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KXS95374.1 - 0.039 13.6 0.1 0.47 10.0 0.1 2.1 1 1 0 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXS95374.1 - 0.07 12.4 0.0 11 5.2 0.0 2.7 2 1 1 3 3 3 0 Serine aminopeptidase, S33 Esterase PF00756.20 KXS95374.1 - 0.11 12.1 0.0 0.28 10.8 0.0 1.6 2 0 0 2 2 2 0 Putative esterase GATase_6 PF13522.6 KXS95375.1 - 1.5e-07 31.6 0.0 2.4e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KXS95375.1 - 1.4e-05 24.2 0.1 4.2e-05 22.6 0.1 1.9 1 1 0 1 1 1 1 Glutamine amidotransferases class-II BAR PF03114.18 KXS95376.1 - 1.6e-49 168.7 11.9 4.8e-19 68.9 0.2 3.1 3 0 0 3 3 3 3 BAR domain Arfaptin PF06456.13 KXS95376.1 - 0.043 13.4 1.8 4.2 6.9 0.0 2.5 3 0 0 3 3 3 0 Arfaptin-like domain MFS_1 PF07690.16 KXS95377.1 - 1e-14 54.2 36.4 9.5e-11 41.2 21.2 2.5 2 1 1 3 3 3 3 Major Facilitator Superfamily CPP1-like PF11833.8 KXS95377.1 - 0.45 10.1 4.3 1.3 8.6 2.3 2.5 1 1 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Fungal_lectin PF07938.12 KXS95378.1 - 0.00065 19.2 0.0 0.00089 18.7 0.0 1.2 1 0 0 1 1 1 1 Fungal fucose-specific lectin DUF4834 PF16118.5 KXS95378.1 - 0.16 13.0 0.9 0.44 11.5 0.1 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4834) NUT PF12881.7 KXS95378.1 - 0.17 10.2 0.4 0.23 9.8 0.4 1.1 1 0 0 1 1 1 0 NUT protein Flu_B_M2 PF04772.12 KXS95379.1 - 0.11 12.7 1.2 0.14 12.5 0.2 1.6 2 0 0 2 2 2 0 Influenza B matrix protein 2 (BM2) Ribosomal_L1 PF00687.21 KXS95380.1 - 1.5e-29 103.2 0.0 1.9e-29 102.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Piwi PF02171.17 KXS95383.1 - 3.5e-57 193.9 0.0 6.1e-57 193.1 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoL1 PF08699.10 KXS95383.1 - 8.3e-08 31.8 0.1 2e-07 30.6 0.1 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain zf-CCHC_4 PF14392.6 KXS95383.1 - 6.1 6.7 8.3 0.87 9.4 0.2 2.6 2 0 0 2 2 2 0 Zinc knuckle DJ-1_PfpI PF01965.24 KXS95384.1 - 6.9e-14 52.0 0.0 1.1e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KXS95384.1 - 0.0042 16.8 0.0 0.006 16.3 0.0 1.2 1 0 0 1 1 1 1 ThiJ/PfpI family-like FMO-like PF00743.19 KXS95385.1 - 1.1e-14 53.8 0.1 2.2e-14 52.8 0.1 1.4 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXS95385.1 - 1.6e-13 50.6 0.0 3.2e-13 49.6 0.0 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXS95385.1 - 2.9e-11 43.1 0.0 4.7e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXS95385.1 - 2.4e-07 30.9 0.0 1e-06 28.9 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXS95385.1 - 5.2e-05 22.6 0.1 0.00012 21.4 0.0 1.6 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 KXS95385.1 - 6.6e-05 22.6 0.3 0.0018 17.9 0.3 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KXS95385.1 - 0.00013 21.5 0.4 0.00052 19.5 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXS95385.1 - 0.00098 19.6 3.5 0.95 10.1 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXS95385.1 - 0.0027 16.9 0.1 0.0039 16.3 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain K_oxygenase PF13434.6 KXS95385.1 - 0.0033 16.6 0.0 0.021 13.9 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KXS95385.1 - 0.0086 16.1 0.1 0.03 14.3 0.1 1.9 1 1 0 1 1 1 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 KXS95385.1 - 0.012 15.0 0.1 0.095 12.0 0.0 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KXS95385.1 - 0.016 14.3 0.0 0.31 10.1 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.14 KXS95385.1 - 0.078 11.7 0.1 0.13 10.9 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.12 KXS95385.1 - 0.13 11.3 0.1 0.19 10.8 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Amino_oxidase PF01593.24 KXS95385.1 - 0.15 11.3 0.3 0.43 9.8 0.0 1.8 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Zn_clus PF00172.18 KXS95386.1 - 6.4e-11 42.2 11.7 1.3e-10 41.2 11.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXS95386.1 - 5.7e-06 25.6 0.0 9.2e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS95387.1 - 6.4e-11 42.2 11.7 1.3e-10 41.2 11.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXS95387.1 - 5.7e-06 25.6 0.0 9.2e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1524 PF07510.11 KXS95388.1 - 7.1e-08 32.4 0.0 1e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) SEP PF08059.13 KXS95390.1 - 5.8e-24 84.5 0.0 1.3e-23 83.4 0.0 1.6 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 KXS95390.1 - 3.3e-14 52.8 0.0 5.2e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 KXS95390.1 - 6.7e-14 51.4 1.3 1.1e-13 50.7 1.3 1.4 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 KXS95390.1 - 0.0026 17.4 0.1 0.0046 16.6 0.1 1.3 1 0 0 1 1 1 1 TAP C-terminal domain TOM13 PF08219.11 KXS95391.1 - 3.3e-38 129.5 0.0 4.2e-38 129.2 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 BioT2 PF15368.6 KXS95391.1 - 0.061 13.3 0.0 0.079 12.9 0.0 1.1 1 0 0 1 1 1 0 Spermatogenesis family BioT2 WSC PF01822.19 KXS95392.1 - 5.5e-100 327.7 113.2 2e-19 69.5 13.9 6.5 6 0 0 6 6 6 6 WSC domain Glyoxal_oxid_N PF07250.11 KXS95392.1 - 9.8e-30 103.5 0.0 3e-28 98.6 0.0 2.7 2 1 1 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KXS95392.1 - 1.3e-21 76.7 0.0 3e-21 75.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_2 PF07646.15 KXS95392.1 - 0.12 12.4 0.5 5 7.3 0.0 3.5 3 0 0 3 3 3 0 Kelch motif PepSY_2 PF13670.6 KXS95392.1 - 2.1 8.4 4.2 29 4.7 0.0 3.4 4 0 0 4 4 4 0 Peptidase propeptide and YPEB domain 60KD_IMP PF02096.20 KXS95395.1 - 5.7e-16 58.9 3.4 5.7e-16 58.9 3.4 1.6 2 0 0 2 2 2 1 60Kd inner membrane protein YtxH PF12732.7 KXS95395.1 - 0.35 11.4 5.7 1.2 9.8 5.7 1.9 1 0 0 1 1 1 0 YtxH-like protein SLATT_fungal PF18142.1 KXS95396.1 - 5.1e-34 116.8 0.7 6.9e-34 116.4 0.7 1.2 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain DUF2263 PF10021.9 KXS95401.1 - 7.1e-15 55.7 1.4 1.9e-14 54.3 0.0 2.4 3 0 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2263) zf-AN1 PF01428.16 KXS95401.1 - 0.16 12.1 1.5 0.32 11.2 1.5 1.4 1 0 0 1 1 1 0 AN1-like Zinc finger FlaE PF07559.14 KXS95402.1 - 0.0054 17.3 1.4 0.01 16.4 1.4 1.5 1 0 0 1 1 1 1 Flagellar basal body protein FlaE PGP_phosphatase PF09419.10 KXS95403.1 - 1.6e-68 229.6 0.0 1.8e-68 229.4 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 KXS95403.1 - 0.00061 19.8 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Ferritin_2 PF13668.6 KXS95404.1 - 7.3e-43 146.0 1.4 1e-42 145.6 0.9 1.5 2 0 0 2 2 2 1 Ferritin-like domain HIRAN PF08797.11 KXS95404.1 - 0.16 11.9 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 HIRAN domain Las1 PF04031.13 KXS95407.1 - 1.3e-47 161.7 3.0 1.6e-47 161.4 0.5 2.2 2 0 0 2 2 2 1 Las1-like Cofilin_ADF PF00241.20 KXS95408.1 - 0.049 13.4 0.0 0.091 12.6 0.0 1.5 1 0 0 1 1 1 0 Cofilin/tropomyosin-type actin-binding protein Chs7 PF12271.8 KXS95409.1 - 3.4e-125 417.2 18.8 3.9e-125 417.0 18.8 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF3671 PF12420.8 KXS95409.1 - 3.2 7.9 7.1 2 8.5 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function DUF3675 PF12428.8 KXS95409.1 - 5 7.7 7.1 3.9 8.1 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3675) Methyltransf_10 PF05971.12 KXS95410.1 - 2.2e-62 211.1 0.0 2.9e-62 210.7 0.0 1.1 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 KXS95410.1 - 1.3e-07 31.3 0.0 3.2e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KXS95410.1 - 0.0012 18.3 0.0 0.0024 17.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KXS95410.1 - 0.0044 17.7 0.0 0.019 15.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.18 KXS95410.1 - 0.012 15.3 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.6 KXS95410.1 - 0.021 14.6 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KXS95410.1 - 0.022 15.5 0.0 0.057 14.2 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 KXS95410.1 - 0.055 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KXS95410.1 - 0.094 13.4 0.0 0.19 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain nsp8 PF08717.10 KXS95410.1 - 0.13 12.2 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 nsp8 replicase Iso_dh PF00180.20 KXS95411.1 - 1.5e-84 284.1 0.0 1.7e-84 283.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF2011 PF09428.10 KXS95415.1 - 9.8e-24 83.4 1.0 2.4e-23 82.2 0.0 2.0 2 1 0 2 2 2 1 Fungal protein of unknown function (DUF2011) Menin PF05053.13 KXS95415.1 - 1.3 7.3 10.2 1.9 6.8 9.4 1.5 2 0 0 2 2 2 0 Menin DUF4407 PF14362.6 KXS95415.1 - 2.5 7.3 9.3 3.8 6.8 9.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Presenilin PF01080.17 KXS95415.1 - 4.3 6.0 4.0 5.5 5.6 4.0 1.1 1 0 0 1 1 1 0 Presenilin LIN37 PF15306.6 KXS95417.1 - 0.1 12.8 0.8 0.15 12.2 0.8 1.3 1 0 0 1 1 1 0 LIN37 NAD_kinase PF01513.21 KXS95418.1 - 2.4e-76 256.7 0.0 4e-76 256.0 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase Adaptin_binding PF10199.9 KXS95419.1 - 3.3e-11 43.9 10.1 3.8e-11 43.7 8.3 1.9 2 0 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 OHCU_decarbox PF09349.10 KXS95420.1 - 9.5e-48 162.6 0.9 1.1e-47 162.4 0.9 1.0 1 0 0 1 1 1 1 OHCU decarboxylase Sulfotransfer_3 PF13469.6 KXS95420.1 - 0.11 12.9 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 Sulfotransferase family NIR_SIR_ferr PF03460.17 KXS95420.1 - 0.18 11.7 0.5 2.1 8.2 0.1 2.6 3 0 0 3 3 3 0 Nitrite/Sulfite reductase ferredoxin-like half domain PIG-L PF02585.17 KXS95421.1 - 4.4e-25 88.8 0.0 6.4e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Peptidase_S24 PF00717.23 KXS95422.1 - 7.2e-07 29.1 0.1 3.6e-06 26.8 0.1 2.0 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 KXS95422.1 - 4.4e-05 23.3 0.0 0.0002 21.2 0.0 2.1 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 GLTP PF08718.11 KXS95423.1 - 7.2e-46 156.2 0.0 8.6e-46 155.9 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) ApoLp-III PF07464.11 KXS95423.1 - 0.096 12.8 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) TRAPP PF04051.16 KXS95424.1 - 1.3e-39 135.2 0.0 1.6e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Cyclin_N PF00134.23 KXS95425.1 - 0.0004 20.1 0.2 0.0044 16.8 0.0 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain zf-CCHC_3 PF13917.6 KXS95425.1 - 0.0004 20.3 0.2 0.00087 19.2 0.2 1.5 1 0 0 1 1 1 1 Zinc knuckle MIF PF01187.18 KXS95426.1 - 3.4e-13 49.9 0.0 5.8e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) PPP4R2 PF09184.11 KXS95426.1 - 0.31 10.6 4.1 0.89 9.1 4.1 1.8 1 1 0 1 1 1 0 PPP4R2 PAP2 PF01569.21 KXS95431.1 - 1.1e-17 64.0 5.5 1.1e-17 64.0 5.5 1.9 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 KXS95431.1 - 0.001 18.8 5.8 0.0022 17.7 5.8 1.6 1 0 0 1 1 1 1 PAP2 superfamily MFS_1 PF07690.16 KXS95432.1 - 6.3e-24 84.6 48.1 1.3e-14 53.9 20.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KXS95433.1 - 1e-25 90.5 19.9 1e-25 90.5 19.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4731 PF15875.5 KXS95433.1 - 0.082 13.1 0.1 27 5.1 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4731) MgtC PF02308.16 KXS95433.1 - 0.26 11.7 6.7 0.86 10.0 0.1 3.0 3 0 0 3 3 3 0 MgtC family MFS_1 PF07690.16 KXS95434.1 - 9.8e-26 90.5 20.0 9.8e-26 90.5 20.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MgtC PF02308.16 KXS95434.1 - 0.19 12.1 6.3 0.84 10.0 0.1 3.0 3 0 0 3 3 3 0 MgtC family MFS_1 PF07690.16 KXS95435.1 - 1.1e-44 152.9 38.1 5.9e-42 143.9 38.8 2.8 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS95435.1 - 6.7e-14 51.6 11.2 6.7e-14 51.6 11.2 3.1 3 1 1 4 4 4 1 Sugar (and other) transporter Arrestin_C PF02752.22 KXS95436.1 - 1.4e-13 51.4 0.0 1.3e-12 48.3 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain ZipA_C PF04354.13 KXS95437.1 - 0.081 12.8 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 ZipA, C-terminal FtsZ-binding domain SOG2 PF10428.9 KXS95438.1 - 0.0002 20.7 0.9 0.00026 20.4 0.9 1.1 1 0 0 1 1 1 1 RAM signalling pathway protein DUF1115 PF06544.12 KXS95440.1 - 4.3e-10 39.9 0.0 7.7e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) MgtE_N PF03448.17 KXS95440.1 - 0.061 13.9 0.2 0.14 12.8 0.2 1.5 1 0 0 1 1 1 0 MgtE intracellular N domain ETC_C1_NDUFA4 PF04800.12 KXS95442.1 - 1.6e-35 121.2 1.2 2.2e-35 120.7 1.2 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region FMO-like PF00743.19 KXS95443.1 - 5.9e-29 100.9 0.0 5.7e-12 44.8 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXS95443.1 - 6e-11 42.1 0.1 2.6e-06 26.9 0.0 3.4 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXS95443.1 - 4.3e-07 29.5 0.0 4.6e-06 26.1 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXS95443.1 - 6.9e-06 25.4 0.0 0.00082 18.6 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KXS95443.1 - 1.7e-05 24.9 0.8 0.00017 21.6 0.2 2.8 2 1 0 2 2 2 1 FAD-NAD(P)-binding HTH_23 PF13384.6 KXS95443.1 - 2e-05 24.3 0.9 3.2 7.6 0.0 4.3 4 0 0 4 4 4 2 Homeodomain-like domain Sigma70_r4 PF04545.16 KXS95443.1 - 0.0001 21.8 0.1 0.031 13.8 0.0 2.9 3 0 0 3 3 3 1 Sigma-70, region 4 Myb_DNA-binding PF00249.31 KXS95443.1 - 0.00034 20.7 0.1 1.2 9.4 0.0 3.3 3 0 0 3 3 3 2 Myb-like DNA-binding domain HTH_20 PF12840.7 KXS95443.1 - 0.00037 20.5 0.3 1 9.5 0.0 3.4 4 0 0 4 4 3 2 Helix-turn-helix domain HTH_38 PF13936.6 KXS95443.1 - 0.00056 19.6 1.7 0.35 10.7 0.2 3.5 3 0 0 3 3 3 1 Helix-turn-helix domain NAD_binding_8 PF13450.6 KXS95443.1 - 0.00087 19.5 0.0 0.003 17.7 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Sigma70_r4_2 PF08281.12 KXS95443.1 - 0.0011 18.6 0.2 0.42 10.3 0.0 3.5 3 0 0 3 3 3 1 Sigma-70, region 4 GcrA PF07750.11 KXS95443.1 - 0.0015 19.0 0.5 1.1 9.6 0.1 3.0 2 1 0 2 2 2 1 GcrA cell cycle regulator MarR_2 PF12802.7 KXS95443.1 - 0.0032 17.3 0.0 1.7 8.6 0.0 2.9 2 0 0 2 2 2 1 MarR family Myb_DNA-bind_6 PF13921.6 KXS95443.1 - 0.0045 17.2 0.1 7.3 6.9 0.0 3.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain HTH_7 PF02796.15 KXS95443.1 - 0.0067 16.5 0.1 0.93 9.6 0.1 3.4 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase HTH_30 PF13556.6 KXS95443.1 - 0.011 15.5 0.1 19 5.2 0.0 3.4 3 0 0 3 3 3 0 PucR C-terminal helix-turn-helix domain DAO PF01266.24 KXS95443.1 - 0.011 15.3 0.0 0.53 9.8 0.0 2.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF1441 PF07278.11 KXS95443.1 - 0.022 14.7 1.4 8.3 6.3 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1441) HTH_8 PF02954.19 KXS95443.1 - 0.037 13.8 0.0 2.9 7.8 0.0 3.1 3 0 0 3 3 3 0 Bacterial regulatory protein, Fis family FMO-like PF00743.19 KXS95444.1 - 5.9e-29 100.9 0.0 5.7e-12 44.8 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXS95444.1 - 6e-11 42.1 0.1 2.6e-06 26.9 0.0 3.4 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXS95444.1 - 4.3e-07 29.5 0.0 4.6e-06 26.1 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXS95444.1 - 6.9e-06 25.4 0.0 0.00082 18.6 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KXS95444.1 - 1.7e-05 24.9 0.8 0.00017 21.6 0.2 2.8 2 1 0 2 2 2 1 FAD-NAD(P)-binding HTH_23 PF13384.6 KXS95444.1 - 2e-05 24.3 0.9 3.2 7.6 0.0 4.3 4 0 0 4 4 4 2 Homeodomain-like domain Sigma70_r4 PF04545.16 KXS95444.1 - 0.0001 21.8 0.1 0.031 13.8 0.0 2.9 3 0 0 3 3 3 1 Sigma-70, region 4 Myb_DNA-binding PF00249.31 KXS95444.1 - 0.00034 20.7 0.1 1.2 9.4 0.0 3.3 3 0 0 3 3 3 2 Myb-like DNA-binding domain HTH_20 PF12840.7 KXS95444.1 - 0.00037 20.5 0.3 1 9.5 0.0 3.4 4 0 0 4 4 3 2 Helix-turn-helix domain HTH_38 PF13936.6 KXS95444.1 - 0.00056 19.6 1.7 0.35 10.7 0.2 3.5 3 0 0 3 3 3 1 Helix-turn-helix domain NAD_binding_8 PF13450.6 KXS95444.1 - 0.00087 19.5 0.0 0.003 17.7 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Sigma70_r4_2 PF08281.12 KXS95444.1 - 0.0011 18.6 0.2 0.42 10.3 0.0 3.5 3 0 0 3 3 3 1 Sigma-70, region 4 GcrA PF07750.11 KXS95444.1 - 0.0015 19.0 0.5 1.1 9.6 0.1 3.0 2 1 0 2 2 2 1 GcrA cell cycle regulator MarR_2 PF12802.7 KXS95444.1 - 0.0032 17.3 0.0 1.7 8.6 0.0 2.9 2 0 0 2 2 2 1 MarR family Myb_DNA-bind_6 PF13921.6 KXS95444.1 - 0.0045 17.2 0.1 7.3 6.9 0.0 3.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain HTH_7 PF02796.15 KXS95444.1 - 0.0067 16.5 0.1 0.93 9.6 0.1 3.4 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase HTH_30 PF13556.6 KXS95444.1 - 0.011 15.5 0.1 19 5.2 0.0 3.4 3 0 0 3 3 3 0 PucR C-terminal helix-turn-helix domain DAO PF01266.24 KXS95444.1 - 0.011 15.3 0.0 0.53 9.8 0.0 2.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF1441 PF07278.11 KXS95444.1 - 0.022 14.7 1.4 8.3 6.3 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1441) HTH_8 PF02954.19 KXS95444.1 - 0.037 13.8 0.0 2.9 7.8 0.0 3.1 3 0 0 3 3 3 0 Bacterial regulatory protein, Fis family FMO-like PF00743.19 KXS95445.1 - 5.9e-29 100.9 0.0 5.7e-12 44.8 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXS95445.1 - 6e-11 42.1 0.1 2.6e-06 26.9 0.0 3.4 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXS95445.1 - 4.3e-07 29.5 0.0 4.6e-06 26.1 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXS95445.1 - 6.9e-06 25.4 0.0 0.00082 18.6 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KXS95445.1 - 1.7e-05 24.9 0.8 0.00017 21.6 0.2 2.8 2 1 0 2 2 2 1 FAD-NAD(P)-binding HTH_23 PF13384.6 KXS95445.1 - 2e-05 24.3 0.9 3.2 7.6 0.0 4.3 4 0 0 4 4 4 2 Homeodomain-like domain Sigma70_r4 PF04545.16 KXS95445.1 - 0.0001 21.8 0.1 0.031 13.8 0.0 2.9 3 0 0 3 3 3 1 Sigma-70, region 4 Myb_DNA-binding PF00249.31 KXS95445.1 - 0.00034 20.7 0.1 1.2 9.4 0.0 3.3 3 0 0 3 3 3 2 Myb-like DNA-binding domain HTH_20 PF12840.7 KXS95445.1 - 0.00037 20.5 0.3 1 9.5 0.0 3.4 4 0 0 4 4 3 2 Helix-turn-helix domain HTH_38 PF13936.6 KXS95445.1 - 0.00056 19.6 1.7 0.35 10.7 0.2 3.5 3 0 0 3 3 3 1 Helix-turn-helix domain NAD_binding_8 PF13450.6 KXS95445.1 - 0.00087 19.5 0.0 0.003 17.7 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Sigma70_r4_2 PF08281.12 KXS95445.1 - 0.0011 18.6 0.2 0.42 10.3 0.0 3.5 3 0 0 3 3 3 1 Sigma-70, region 4 GcrA PF07750.11 KXS95445.1 - 0.0015 19.0 0.5 1.1 9.6 0.1 3.0 2 1 0 2 2 2 1 GcrA cell cycle regulator MarR_2 PF12802.7 KXS95445.1 - 0.0032 17.3 0.0 1.7 8.6 0.0 2.9 2 0 0 2 2 2 1 MarR family Myb_DNA-bind_6 PF13921.6 KXS95445.1 - 0.0045 17.2 0.1 7.3 6.9 0.0 3.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain HTH_7 PF02796.15 KXS95445.1 - 0.0067 16.5 0.1 0.93 9.6 0.1 3.4 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase HTH_30 PF13556.6 KXS95445.1 - 0.011 15.5 0.1 19 5.2 0.0 3.4 3 0 0 3 3 3 0 PucR C-terminal helix-turn-helix domain DAO PF01266.24 KXS95445.1 - 0.011 15.3 0.0 0.53 9.8 0.0 2.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF1441 PF07278.11 KXS95445.1 - 0.022 14.7 1.4 8.3 6.3 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1441) HTH_8 PF02954.19 KXS95445.1 - 0.037 13.8 0.0 2.9 7.8 0.0 3.1 3 0 0 3 3 3 0 Bacterial regulatory protein, Fis family Pex2_Pex12 PF04757.14 KXS95448.1 - 1.6e-51 175.0 1.0 2.2e-51 174.6 1.0 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 KXS95448.1 - 0.0092 16.1 0.6 0.017 15.3 0.6 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KXS95448.1 - 0.015 15.1 0.4 0.028 14.2 0.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXS95448.1 - 0.032 14.1 0.2 0.058 13.3 0.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXS95448.1 - 0.05 14.0 0.2 0.09 13.1 0.2 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.25 KXS95448.1 - 0.1 12.5 0.2 0.18 11.7 0.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-FPG_IleRS PF06827.14 KXS95448.1 - 0.12 12.3 0.7 0.25 11.3 0.7 1.6 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS RGS-like PF09128.11 KXS95449.1 - 0.085 12.6 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain BPL_N PF09825.9 KXS95450.1 - 9e-12 44.7 1.6 1.1e-07 31.3 0.7 2.2 1 1 1 2 2 2 2 Biotin-protein ligase, N terminal Tfb4 PF03850.14 KXS95451.1 - 8.4e-101 337.1 0.0 9.9e-101 336.8 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 DUF3567 PF12091.8 KXS95452.1 - 0.13 12.4 0.0 0.33 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3567) Top6b_C PF18000.1 KXS95453.1 - 0.11 12.7 0.1 4.5 7.5 0.0 2.8 3 0 0 3 3 3 0 Type 2 DNA topoisomerase 6 subunit B C-terminal domain PEP-CTERM PF07589.11 KXS95455.1 - 9.9 6.4 8.1 31 4.9 0.0 2.4 2 0 0 2 2 2 0 PEP-CTERM motif Pro_isomerase PF00160.21 KXS95457.1 - 3.6e-49 167.1 0.0 4.1e-49 166.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF1772 PF08592.11 KXS95458.1 - 5.5e-13 49.4 0.5 8e-13 48.9 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) PALP PF00291.25 KXS95460.1 - 5.5e-33 114.6 0.0 1.1e-32 113.7 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Rhodanese PF00581.20 KXS95460.1 - 0.061 13.9 0.0 0.2 12.2 0.0 1.9 1 0 0 1 1 1 0 Rhodanese-like domain DASH_Dad1 PF08649.10 KXS95461.1 - 2.4e-25 88.5 1.4 3.3e-25 88.0 1.4 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad1 WVELL PF14043.6 KXS95461.1 - 0.037 13.8 0.3 0.1 12.5 0.0 1.9 3 0 0 3 3 3 0 WVELL protein Ras PF00071.22 KXS95462.1 - 1.3e-48 164.7 0.0 1.8e-48 164.2 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXS95462.1 - 1.4e-19 70.5 0.0 2.5e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXS95462.1 - 8.8e-05 22.0 0.0 0.00016 21.2 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_7 PF12775.7 KXS95462.1 - 0.023 14.2 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region SRPRB PF09439.10 KXS95462.1 - 0.17 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AtuA PF07287.11 KXS95463.1 - 3.2e-134 447.1 0.1 3.8e-134 446.8 0.1 1.0 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Mito_carr PF00153.27 KXS95467.1 - 7.3e-45 150.8 7.5 1e-17 63.8 0.4 4.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KXS95467.1 - 0.00045 19.5 1.4 0.07 12.3 0.1 2.5 2 1 0 2 2 2 2 Gammaproteobacterial serine protease CxC7 PF18866.1 KXS95468.1 - 0.06 13.5 1.5 0.086 13.0 0.6 1.6 1 1 1 2 2 2 0 CxC7 like cysteine cluster associated with KDZ transposases DUF1664 PF07889.12 KXS95469.1 - 0.0091 16.0 13.5 0.044 13.8 1.5 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1664) DUF641 PF04859.12 KXS95469.1 - 1.6 9.1 25.2 5.6 7.3 5.3 3.2 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) Mvb12 PF09452.10 KXS95469.1 - 2.2 8.8 9.2 0.1 13.1 0.7 2.8 2 1 1 3 3 3 0 ESCRT-I subunit Mvb12 T3SSipB PF16535.5 KXS95469.1 - 7 7.1 13.1 0.24 11.9 5.2 2.7 2 0 0 2 2 2 0 Type III cell invasion protein SipB Filament PF00038.21 KXS95469.1 - 7.9 6.0 43.3 0.041 13.5 10.5 3.4 2 1 1 3 3 3 0 Intermediate filament protein Aa_trans PF01490.18 KXS95470.1 - 1.5e-07 30.5 0.1 1.7e-07 30.3 0.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 KXS95470.1 - 0.00015 20.8 0.2 0.00015 20.7 0.2 1.1 1 0 0 1 1 1 1 Amino acid permease Spore_permease PF03845.13 KXS95470.1 - 0.034 13.0 0.1 0.045 12.6 0.1 1.1 1 0 0 1 1 1 0 Spore germination protein DTHCT PF08070.11 KXS95471.1 - 0.14 12.9 22.7 0.11 13.2 21.6 1.4 1 1 0 1 1 1 0 DTHCT (NUC029) region Pns11_12 PF17464.2 KXS95471.1 - 0.85 9.3 11.0 0.96 9.1 11.0 1.2 1 0 0 1 1 1 0 Non-structural protein 11 and 12 MCM_bind PF09739.9 KXS95471.1 - 1.1 7.6 7.0 1.3 7.4 7.0 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Presenilin PF01080.17 KXS95471.1 - 2.2 7.0 6.5 2.4 6.8 6.5 1.0 1 0 0 1 1 1 0 Presenilin RNA_pol_Rpc4 PF05132.14 KXS95471.1 - 2.5 8.5 8.5 3.5 8.1 8.5 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Zip PF02535.22 KXS95471.1 - 8 5.6 4.7 9.3 5.4 4.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter NPR3 PF03666.13 KXS95471.1 - 9.5 4.9 10.4 11 4.7 10.4 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Macro PF01661.21 KXS95472.1 - 1.8e-20 73.2 0.0 3.9e-20 72.1 0.0 1.6 2 0 0 2 2 2 1 Macro domain Presenilin PF01080.17 KXS95472.1 - 0.12 11.2 0.3 0.088 11.6 0.3 1.1 1 0 0 1 1 1 0 Presenilin XRCC4 PF06632.12 KXS95472.1 - 4.3 6.1 9.2 5.2 5.8 9.2 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 PAT1 PF09770.9 KXS95473.1 - 0 1022.2 0.0 0 1021.9 0.0 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 PDE4_UCR PF18100.1 KXS95473.1 - 0.2 12.3 0.0 0.44 11.2 0.0 1.5 1 0 0 1 1 1 0 Phosphodiesterase 4 upstream conserved regions (UCR) Rieske PF00355.26 KXS95474.1 - 2.8e-11 43.2 0.0 6.4e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 KXS95474.1 - 9.1e-10 38.9 0.2 3.2e-09 37.1 0.2 2.0 1 1 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region DUF1353 PF07087.11 KXS95474.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1353) Glycos_transf_1 PF00534.20 KXS95475.1 - 2.1e-31 108.8 0.0 3.7e-29 101.5 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KXS95475.1 - 1.4e-15 57.7 0.0 2.5e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KXS95475.1 - 1.6e-14 54.5 0.0 1.2e-13 51.6 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KXS95475.1 - 2.4e-05 24.8 0.0 6.2e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KXS95475.1 - 0.00042 20.6 0.0 0.00083 19.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 ALG11_N PF15924.5 KXS95475.1 - 0.019 15.0 0.3 1.7 8.7 0.1 2.6 2 1 0 2 2 2 0 ALG11 mannosyltransferase N-terminus Glyco_trans_4_5 PF16994.5 KXS95475.1 - 0.063 12.9 0.0 0.17 11.5 0.0 1.7 2 0 0 2 2 2 0 Glycosyl-transferase family 4 Glyphos_transf PF04464.14 KXS95475.1 - 0.11 11.5 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase Glyco_transf_15 PF01793.16 KXS95476.1 - 5.7e-130 433.3 7.7 7.1e-130 433.0 7.7 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase EGF_3 PF12947.7 KXS95476.1 - 0.18 12.0 2.5 0.33 11.2 2.5 1.4 1 0 0 1 1 1 0 EGF domain Acyltransferase PF01553.21 KXS95477.1 - 1.8e-16 60.0 0.0 3.3e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase DUF92 PF01940.16 KXS95478.1 - 2e-73 246.7 13.4 2.3e-73 246.5 13.4 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 WW_like PF17890.1 KXS95478.1 - 0.15 12.2 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Peptidoglycan hydrolase LytB WW-like domain Peptidase_A8 PF01252.18 KXS95478.1 - 0.59 10.4 4.8 0.33 11.2 0.4 2.5 2 1 1 3 3 3 0 Signal peptidase (SPase) II AIRC PF00731.20 KXS95482.1 - 1.4e-56 190.2 0.8 2.5e-56 189.4 0.8 1.4 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 KXS95482.1 - 5e-49 166.2 0.0 9.2e-49 165.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 KXS95482.1 - 9.1e-18 63.7 0.1 2.1e-17 62.6 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain 2-Hacid_dh_C PF02826.19 KXS95482.1 - 0.0031 16.9 0.0 0.0063 15.9 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Dala_Dala_lig_C PF07478.13 KXS95482.1 - 0.0039 16.8 0.0 0.016 14.8 0.0 1.9 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus AlaDh_PNT_C PF01262.21 KXS95482.1 - 0.011 15.0 0.2 0.026 13.8 0.2 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain VirE_N PF08800.10 KXS95482.1 - 0.012 15.8 0.1 0.042 14.0 0.0 1.9 2 0 0 2 2 2 0 VirE N-terminal domain AIRC PF00731.20 KXS95483.1 - 1.4e-56 190.1 0.8 2.5e-56 189.4 0.8 1.4 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 KXS95483.1 - 5e-49 166.2 0.0 9.2e-49 165.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 KXS95483.1 - 9.1e-18 63.7 0.1 2.1e-17 62.6 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain 2-Hacid_dh_C PF02826.19 KXS95483.1 - 0.0032 16.9 0.0 0.0064 15.9 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Dala_Dala_lig_C PF07478.13 KXS95483.1 - 0.0039 16.7 0.0 0.016 14.8 0.0 1.9 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus AlaDh_PNT_C PF01262.21 KXS95483.1 - 0.011 15.0 0.2 0.026 13.8 0.2 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain VirE_N PF08800.10 KXS95483.1 - 0.012 15.7 0.1 0.043 13.9 0.0 1.9 2 0 0 2 2 2 0 VirE N-terminal domain AIRC PF00731.20 KXS95484.1 - 1.4e-56 190.2 0.8 2.5e-56 189.4 0.8 1.4 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 KXS95484.1 - 5e-49 166.2 0.0 9.2e-49 165.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 KXS95484.1 - 9.1e-18 63.7 0.1 2.1e-17 62.6 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain 2-Hacid_dh_C PF02826.19 KXS95484.1 - 0.0031 16.9 0.0 0.0063 15.9 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Dala_Dala_lig_C PF07478.13 KXS95484.1 - 0.0039 16.8 0.0 0.016 14.8 0.0 1.9 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus AlaDh_PNT_C PF01262.21 KXS95484.1 - 0.011 15.0 0.2 0.026 13.8 0.2 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain VirE_N PF08800.10 KXS95484.1 - 0.012 15.8 0.1 0.042 14.0 0.0 1.9 2 0 0 2 2 2 0 VirE N-terminal domain Ribosomal_L18 PF17135.4 KXS95485.1 - 1.3e-86 288.8 1.1 1.5e-86 288.6 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 KXS95485.1 - 0.00041 21.0 0.7 0.002 18.8 0.7 2.4 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Nudc_N PF14050.6 KXS95485.1 - 0.15 12.0 0.0 0.47 10.5 0.0 1.7 1 0 0 1 1 1 0 N-terminal conserved domain of Nudc. YrhK PF14145.6 KXS95487.1 - 0.1 12.5 20.6 0.22 11.4 4.1 3.3 3 2 0 3 3 3 0 YrhK-like protein DNase_NucA_NucB PF14040.6 KXS95490.1 - 3.2e-06 27.5 7.0 0.00013 22.3 7.0 2.6 1 1 0 1 1 1 1 Deoxyribonuclease NucA/NucB Patatin PF01734.22 KXS95492.1 - 4.5e-17 62.9 0.1 2.5e-11 44.1 0.0 3.1 2 1 0 2 2 2 2 Patatin-like phospholipase DNA_pol_E_B PF04042.16 KXS95493.1 - 6.9e-48 162.8 0.1 1.1e-47 162.1 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B AbiJ_NTD5 PF18865.1 KXS95493.1 - 0.046 13.5 0.0 0.98 9.3 0.0 2.7 2 0 0 2 2 2 0 AbiJ N-terminal domain 5 Fmp27_WPPW PF10359.9 KXS95493.1 - 0.58 8.9 3.3 1.2 7.9 3.3 1.4 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF2464 PF10240.9 KXS95493.1 - 0.73 9.4 2.1 1.2 8.6 1.5 1.5 1 1 0 1 1 1 0 Multivesicular body subunit 12 Ribosomal_L27e PF01777.18 KXS95494.1 - 2.3e-36 124.0 3.9 2.3e-36 124.0 3.9 1.7 2 0 0 2 2 2 1 Ribosomal L27e protein family KOW PF00467.29 KXS95494.1 - 0.044 13.7 0.7 0.095 12.7 0.1 1.9 2 0 0 2 2 2 0 KOW motif SHNi-TPR PF10516.9 KXS95498.1 - 6.8e-14 51.0 0.5 6.8e-14 51.0 0.5 1.9 2 0 0 2 2 2 1 SHNi-TPR CCDC-167 PF15188.6 KXS95498.1 - 0.0094 16.3 3.0 0.054 13.8 3.0 2.4 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 167 TPR_12 PF13424.6 KXS95498.1 - 0.023 15.0 5.3 0.47 10.8 1.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat CENP-F_leu_zip PF10473.9 KXS95498.1 - 0.039 14.0 1.7 0.039 14.0 1.7 3.8 3 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_1 PF00515.28 KXS95498.1 - 0.05 13.4 4.6 0.72 9.8 1.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXS95498.1 - 0.14 12.3 11.8 1.8 8.9 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Gas_vesicle_C PF01304.17 KXS95498.1 - 0.19 11.7 1.7 0.63 10.1 1.7 1.9 1 0 0 1 1 1 0 Gas vesicles protein GVPc repeated domain JIP_LZII PF16471.5 KXS95498.1 - 0.24 11.6 10.5 0.47 10.7 0.6 3.1 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II DUF1664 PF07889.12 KXS95498.1 - 4.2 7.4 5.7 3.5 7.7 1.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 KXS95498.1 - 6.1 7.3 7.6 1 9.8 2.5 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Fungal_trans_2 PF11951.8 KXS95501.1 - 1.1e-05 24.4 0.1 1.4e-05 24.1 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3770 PF12603.8 KXS95503.1 - 0.03 13.8 0.3 0.052 13.0 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3770) DUF4551 PF15087.6 KXS95503.1 - 0.36 9.6 5.2 0.51 9.1 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) PBP_sp32 PF07222.12 KXS95503.1 - 0.92 8.9 7.7 1.4 8.3 7.7 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 PP2C PF00481.21 KXS95504.1 - 3.8e-52 177.5 0.0 6.5e-52 176.7 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 KXS95504.1 - 9.6e-39 131.0 70.7 8e-10 38.3 2.9 11.7 6 4 9 15 15 15 12 Leucine rich repeat LRR_4 PF12799.7 KXS95504.1 - 1.1e-35 121.1 68.8 2.8e-05 24.4 1.6 13.6 7 3 9 17 17 17 12 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 KXS95504.1 - 8.8e-30 103.7 0.0 3e-29 101.9 0.0 1.8 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.33 KXS95504.1 - 7.4e-08 31.9 46.9 2.3 9.1 0.1 15.7 17 3 0 17 17 15 3 Leucine Rich Repeat Ad_cyc_g-alpha PF08509.11 KXS95504.1 - 6.8e-07 28.9 0.7 2.1e-06 27.3 0.3 2.1 2 0 0 2 2 2 1 Adenylate cyclase G-alpha binding domain LRR_9 PF14580.6 KXS95504.1 - 6.8e-06 25.7 14.8 0.21 11.1 0.1 5.0 2 1 2 4 4 4 3 Leucine-rich repeat LRR_5 PF13306.6 KXS95504.1 - 2.3e-05 24.4 1.1 0.33 10.9 0.1 4.0 4 0 0 4 4 4 1 BspA type Leucine rich repeat region (6 copies) RA PF00788.23 KXS95504.1 - 6.5e-05 23.5 0.0 0.0002 21.9 0.0 1.8 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain HTH_34 PF13601.6 KXS95504.1 - 0.063 13.5 0.4 0.33 11.2 0.0 2.2 2 0 0 2 2 2 0 Winged helix DNA-binding domain LRR_6 PF13516.6 KXS95504.1 - 0.23 11.6 51.1 3.3 8.0 0.2 13.6 14 0 0 14 14 13 0 Leucine Rich repeat PP2C PF00481.21 KXS95505.1 - 3.7e-52 177.5 0.0 6.4e-52 176.7 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 KXS95505.1 - 8.2e-39 131.2 70.7 7.6e-10 38.4 2.8 11.7 6 4 9 15 15 15 12 Leucine rich repeat LRR_4 PF12799.7 KXS95505.1 - 8.7e-36 121.4 68.8 2.8e-05 24.4 1.6 13.6 7 3 9 17 17 17 12 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 KXS95505.1 - 8.6e-30 103.7 0.0 2.9e-29 102.0 0.0 1.8 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.33 KXS95505.1 - 6.4e-08 32.1 47.0 2.2 9.1 0.1 15.7 17 3 0 17 17 15 3 Leucine Rich Repeat Ad_cyc_g-alpha PF08509.11 KXS95505.1 - 6.7e-07 28.9 0.7 2.1e-06 27.4 0.3 2.1 2 0 0 2 2 2 1 Adenylate cyclase G-alpha binding domain LRR_9 PF14580.6 KXS95505.1 - 6.4e-06 25.8 14.9 0.2 11.2 0.2 5.0 2 1 2 4 4 4 3 Leucine-rich repeat LRR_5 PF13306.6 KXS95505.1 - 2.2e-05 24.4 1.1 0.33 10.9 0.1 4.0 4 0 0 4 4 4 1 BspA type Leucine rich repeat region (6 copies) RA PF00788.23 KXS95505.1 - 6.3e-05 23.5 0.0 0.0002 21.9 0.0 1.8 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain HTH_34 PF13601.6 KXS95505.1 - 0.061 13.5 0.4 0.32 11.2 0.0 2.2 2 0 0 2 2 2 0 Winged helix DNA-binding domain LRR_6 PF13516.6 KXS95505.1 - 0.19 11.8 51.1 3.3 8.0 0.2 13.6 14 0 0 14 14 13 0 Leucine Rich repeat Amidohydro_1 PF01979.20 KXS95506.1 - 2.6e-26 92.8 0.0 6e-26 91.6 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXS95506.1 - 1e-11 45.0 0.2 8.8e-07 28.7 0.0 2.5 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_2 PF04909.14 KXS95506.1 - 0.033 14.0 0.0 0.099 12.4 0.0 1.7 1 1 0 1 1 1 0 Amidohydrolase Fungal_trans_2 PF11951.8 KXS95507.1 - 0.00022 20.1 0.1 0.00033 19.6 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS95507.1 - 0.1 12.7 1.4 0.2 11.8 1.4 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain NpwBP PF12622.7 KXS95508.1 - 0.0084 16.9 0.1 0.022 15.5 0.1 1.7 1 0 0 1 1 1 1 mRNA biogenesis factor Ribosomal_60s PF00428.19 KXS95508.1 - 1.2 9.8 22.2 0.12 13.0 15.5 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein Fungal_trans_2 PF11951.8 KXS95509.1 - 0.00044 19.2 0.2 0.00095 18.1 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain NpwBP PF12622.7 KXS95509.1 - 0.013 16.2 0.1 0.054 14.3 0.1 2.0 1 0 0 1 1 1 0 mRNA biogenesis factor NpwBP PF12622.7 KXS95510.1 - 0.0084 16.8 0.1 0.021 15.6 0.1 1.6 1 0 0 1 1 1 1 mRNA biogenesis factor Ribosomal_60s PF00428.19 KXS95510.1 - 1.1 9.8 22.2 0.12 13.0 15.5 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein Fungal_trans_2 PF11951.8 KXS95511.1 - 0.00022 20.1 0.1 0.00033 19.6 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS95511.1 - 0.1 12.7 1.4 0.2 11.8 1.4 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Tyrosinase PF00264.20 KXS95512.1 - 9.8e-42 143.7 1.9 1.8e-41 142.9 1.9 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 KXS95512.1 - 2.2e-31 109.1 0.0 2.2e-30 105.8 0.0 2.1 2 0 0 2 2 2 1 Tyosinase C-terminal domain DUF1917 PF08939.10 KXS95513.1 - 1.4e-59 202.2 0.0 1.8e-59 201.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) Ferritin PF00210.24 KXS95514.1 - 0.00024 21.0 0.2 0.00057 19.8 0.2 1.7 1 0 0 1 1 1 1 Ferritin-like domain FUSC PF04632.12 KXS95514.1 - 0.96 7.9 4.4 1.4 7.3 4.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Amino_oxidase PF01593.24 KXS95515.1 - 4.6e-31 108.6 0.1 9.2e-24 84.5 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXS95515.1 - 2e-12 47.2 0.0 5.7e-12 45.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXS95515.1 - 3.2e-07 30.3 0.2 3.2e-06 27.0 0.0 2.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase MCRA PF06100.11 KXS95515.1 - 0.0023 16.8 0.0 0.0044 15.9 0.0 1.4 1 0 0 1 1 1 1 MCRA family Pyr_redox PF00070.27 KXS95515.1 - 0.0093 16.5 0.0 0.09 13.3 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXS95515.1 - 0.011 14.9 0.0 0.032 13.5 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Pyr_redox_2 PF07992.14 KXS95515.1 - 0.032 13.4 0.0 0.11 11.7 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DNA_primase_S PF01896.19 KXS95516.1 - 7.5e-61 205.2 0.2 7.5e-61 205.2 0.2 2.2 3 0 0 3 3 3 1 DNA primase small subunit MOSC PF03473.17 KXS95518.1 - 1.6e-32 112.3 0.0 2.3e-32 111.8 0.0 1.2 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KXS95518.1 - 1.4e-12 47.6 0.0 2.3e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain FAD_binding_3 PF01494.19 KXS95521.1 - 1.4e-15 57.4 0.2 8.1e-14 51.6 0.2 2.1 1 1 0 1 1 1 1 FAD binding domain ABATE PF07336.11 KXS95521.1 - 0.11 13.2 1.3 0.11 13.2 0.1 1.6 2 0 0 2 2 2 0 Putative stress-induced transcription regulator Patatin PF01734.22 KXS95525.1 - 3.5e-16 60.0 0.0 7.4e-16 58.9 0.0 1.5 1 1 0 1 1 1 1 Patatin-like phospholipase p450 PF00067.22 KXS95527.1 - 7.7e-59 199.6 0.0 1.1e-58 199.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AAA PF00004.29 KXS95529.1 - 3.9e-60 202.1 0.0 2.4e-41 141.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXS95529.1 - 3.6e-15 55.5 0.8 1.8e-06 27.6 0.1 2.7 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 KXS95529.1 - 4.8e-09 36.8 0.0 0.012 16.0 0.1 3.8 2 2 0 3 3 3 2 AAA ATPase domain AAA_2 PF07724.14 KXS95529.1 - 1.1e-06 28.9 0.0 0.01 16.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KXS95529.1 - 1.2e-05 25.6 0.6 1.2 9.4 0.0 4.2 2 2 2 4 4 4 2 AAA domain AAA_5 PF07728.14 KXS95529.1 - 3.3e-05 23.9 0.0 0.0013 18.8 0.0 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KXS95529.1 - 0.00013 21.6 0.0 0.61 9.6 0.0 2.5 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_14 PF13173.6 KXS95529.1 - 0.00016 21.7 0.0 0.27 11.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 KXS95529.1 - 0.0004 20.1 0.0 0.17 11.6 0.0 2.9 2 1 0 2 2 2 1 Sigma-54 interaction domain TIP49 PF06068.13 KXS95529.1 - 0.00041 19.7 0.1 0.025 13.8 0.0 2.6 3 0 0 3 3 3 1 TIP49 P-loop domain Sigma54_activ_2 PF14532.6 KXS95529.1 - 0.00044 20.4 0.0 1.3 9.1 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain CDC48_N PF02359.18 KXS95529.1 - 0.0012 19.0 0.0 0.0037 17.4 0.0 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain NACHT PF05729.12 KXS95529.1 - 0.0042 17.0 0.2 3.1 7.7 0.0 3.8 4 0 0 4 4 4 1 NACHT domain AAA_23 PF13476.6 KXS95529.1 - 0.0073 16.8 0.0 0.014 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KXS95529.1 - 0.0088 15.8 0.0 0.19 11.5 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain ATPase_2 PF01637.18 KXS95529.1 - 0.015 15.2 0.0 1.2 9.0 0.0 2.7 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea Bac_DnaA PF00308.18 KXS95529.1 - 0.026 14.4 0.0 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 Bacterial dnaA protein AAA_28 PF13521.6 KXS95529.1 - 0.028 14.7 0.0 4.1 7.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KXS95529.1 - 0.036 14.0 0.2 0.079 12.9 0.2 1.5 1 0 0 1 1 1 0 RsgA GTPase RNA_helicase PF00910.22 KXS95529.1 - 0.043 14.2 0.0 6 7.3 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.6 KXS95529.1 - 0.057 14.0 0.0 3.4 8.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KXS95529.1 - 0.062 12.9 0.0 6.9 6.2 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KXS95529.1 - 0.093 12.4 0.0 2.3 7.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KXS95529.1 - 0.1 12.4 0.0 4.1 7.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Vps4_C PF09336.10 KXS95529.1 - 0.11 12.5 0.0 0.55 10.3 0.0 2.2 2 0 0 2 2 1 0 Vps4 C terminal oligomerisation domain AAA_3 PF07726.11 KXS95529.1 - 0.12 12.2 0.0 4.5 7.1 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 KXS95529.1 - 0.13 11.4 0.0 7.8 5.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Rad17 PF03215.15 KXS95529.1 - 0.2 11.6 0.1 1.1 9.1 0.0 2.1 2 1 1 3 3 3 0 Rad17 P-loop domain Ras PF00071.22 KXS95530.1 - 2.2e-65 219.2 0.1 2.7e-65 218.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXS95530.1 - 7.1e-34 116.6 0.0 1.1e-33 116.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXS95530.1 - 3.9e-13 49.2 0.0 4.8e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KXS95530.1 - 1e-05 25.2 0.0 2.2e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KXS95530.1 - 0.00022 20.7 0.0 0.00027 20.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KXS95530.1 - 0.0035 17.4 0.0 0.008 16.3 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXS95530.1 - 0.004 17.1 0.2 2.7 7.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 KXS95530.1 - 0.025 14.0 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 KXS95530.1 - 0.042 13.4 0.0 0.21 11.1 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA PF00004.29 KXS95530.1 - 0.056 13.9 0.0 7.8 6.9 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXS95530.1 - 0.12 12.6 0.1 0.76 10.0 0.0 2.0 1 1 0 2 2 2 0 AAA domain Glyco_hyd_65N_2 PF14498.6 KXS95532.1 - 3.6e-55 187.4 0.0 5.3e-55 186.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65N PF03636.15 KXS95532.1 - 0.0077 15.9 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain UCH PF00443.29 KXS95533.1 - 3.5e-38 131.6 0.0 3.4e-33 115.2 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXS95533.1 - 1.6e-11 44.4 0.1 6.2e-11 42.4 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF2201_N PF13203.6 KXS95533.1 - 0.027 14.1 0.0 0.057 13.0 0.0 1.5 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF1660 PF07874.11 KXS95533.1 - 0.29 11.7 1.0 0.72 10.4 0.2 2.0 2 0 0 2 2 2 0 Prophage protein (DUF1660) Cyclin_N PF00134.23 KXS95534.1 - 2.2e-14 53.3 0.2 4.1e-13 49.2 0.1 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Peptidase_M29 PF02073.15 KXS95534.1 - 0.14 10.9 0.1 0.21 10.3 0.1 1.1 1 0 0 1 1 1 0 Thermophilic metalloprotease (M29) Ribosomal_L9_N PF01281.19 KXS95535.1 - 1.1e-10 40.8 0.0 3.1e-10 39.4 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L9, N-terminal domain Ribosomal_L9_C PF03948.14 KXS95535.1 - 0.0079 16.6 0.0 0.023 15.2 0.0 1.7 1 1 0 1 1 1 1 Ribosomal protein L9, C-terminal domain NCA2 PF08637.10 KXS95536.1 - 1.1e-108 362.9 0.5 1.8e-108 362.1 0.5 1.3 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 Sugar_tr PF00083.24 KXS95538.1 - 5.1e-74 249.8 17.1 5.8e-74 249.6 17.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS95538.1 - 9.2e-12 44.5 30.5 5.3e-11 42.0 25.7 2.7 1 1 2 3 3 3 3 Major Facilitator Superfamily Hydrolase_4 PF12146.8 KXS95539.1 - 1.9e-06 27.3 0.0 9.1e-06 25.1 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXS95539.1 - 7.9e-06 25.7 0.0 0.00012 21.9 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KXS95539.1 - 0.11 12.6 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein TMA7 PF09072.10 KXS95541.1 - 3.2e-17 63.1 16.6 3.4e-17 63.0 16.6 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 DUF1178 PF06676.11 KXS95542.1 - 0.0053 17.1 0.3 0.0077 16.6 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1178) zf-MIZ PF02891.20 KXS95542.1 - 0.23 11.3 7.9 1.6 8.6 2.4 2.6 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger zf-C3HC4_2 PF13923.6 KXS95542.1 - 0.62 10.0 8.1 1.9 8.4 1.8 2.8 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXS95542.1 - 4.3 7.3 8.9 5.9 6.8 1.2 2.6 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 PAP_RNA-bind PF04926.15 KXS95544.1 - 0.054 13.1 0.0 0.057 13.0 0.0 1.1 1 0 0 1 1 1 0 Poly(A) polymerase predicted RNA binding domain SKG6 PF08693.10 KXS95548.1 - 4.6e-05 22.7 2.0 0.00012 21.4 2.0 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.11 KXS95548.1 - 0.0032 17.6 7.4 0.0047 17.0 7.3 1.5 1 1 0 1 1 1 1 Podoplanin DUF4448 PF14610.6 KXS95548.1 - 0.0033 17.2 0.0 0.0054 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) VSP PF03302.13 KXS95548.1 - 0.032 13.1 0.2 0.052 12.4 0.2 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein Stevor PF17410.2 KXS95548.1 - 0.034 13.7 1.1 0.047 13.2 1.1 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Gram_pos_anchor PF00746.21 KXS95548.1 - 0.037 14.0 0.9 0.11 12.5 0.9 1.8 1 0 0 1 1 1 0 LPXTG cell wall anchor motif PTP_tm PF18861.1 KXS95548.1 - 0.12 12.3 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Amnionless PF14828.6 KXS95548.1 - 0.14 11.0 0.3 0.19 10.5 0.3 1.2 1 0 0 1 1 1 0 Amnionless PGF-CTERM PF18204.1 KXS95548.1 - 0.21 11.6 3.3 0.56 10.2 3.3 1.8 1 0 0 1 1 1 0 PGF-CTERM motif Mid2 PF04478.12 KXS95548.1 - 1.2 8.9 6.6 0.43 10.4 2.3 2.1 1 1 1 2 2 2 0 Mid2 like cell wall stress sensor MGC-24 PF05283.11 KXS95548.1 - 1.9 9.0 8.6 0.14 12.6 3.5 1.7 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin AJAP1_PANP_C PF15298.6 KXS95548.1 - 3.5 7.8 12.3 0.15 12.2 6.3 1.7 2 0 0 2 2 2 0 AJAP1/PANP C-terminus Pro-kuma_activ PF09286.11 KXS95550.1 - 2.1e-43 148.0 0.0 2.2e-41 141.5 0.0 2.4 2 0 0 2 2 2 2 Pro-kumamolisin, activation domain Bax1-I PF01027.20 KXS95551.1 - 3.9e-52 177.1 30.4 4.5e-52 176.9 30.4 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 SfLAP PF11139.8 KXS95551.1 - 0.017 14.6 0.2 0.017 14.6 0.2 2.9 3 1 0 3 3 3 0 Sap, sulfolipid-1-addressing protein DUF3754 PF12576.8 KXS95551.1 - 0.11 12.5 0.3 0.29 11.1 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3754) Spore_YhaL PF14147.6 KXS95551.1 - 0.12 12.1 0.1 0.38 10.5 0.1 1.8 1 0 0 1 1 1 0 Sporulation protein YhaL SARAF PF06682.12 KXS95553.1 - 0.0076 15.9 1.4 0.011 15.4 1.4 1.2 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis MGC-24 PF05283.11 KXS95553.1 - 9.6 6.7 8.1 0.16 12.4 0.5 1.9 2 1 1 3 3 3 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Ank_2 PF12796.7 KXS95554.1 - 1.5e-42 144.0 15.0 2.5e-11 44.0 0.3 7.5 3 2 3 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS95554.1 - 1.5e-31 108.3 10.3 3.6e-09 37.0 0.1 8.9 5 3 3 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS95554.1 - 2e-29 98.4 11.7 0.0098 16.3 0.1 10.5 10 0 0 10 10 9 8 Ankyrin repeat Ank_5 PF13857.6 KXS95554.1 - 4.8e-27 93.7 22.2 5.5e-09 36.1 1.2 9.8 5 3 5 10 10 10 7 Ankyrin repeats (many copies) Ank PF00023.30 KXS95554.1 - 6.5e-25 86.4 25.8 5.8e-05 23.4 0.2 10.0 11 0 0 11 11 11 6 Ankyrin repeat Hydrolase_4 PF12146.8 KXS95554.1 - 0.002 17.4 0.0 0.0092 15.3 0.0 2.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXS95554.1 - 0.0066 17.1 0.5 0.029 15.0 0.0 2.4 3 0 0 3 3 2 1 Alpha/beta hydrolase family DUF676 PF05057.14 KXS95554.1 - 0.0071 15.9 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) AAA_22 PF13401.6 KXS95554.1 - 0.026 14.8 0.0 0.12 12.6 0.0 2.2 1 0 0 1 1 1 0 AAA domain PGAP1 PF07819.13 KXS95554.1 - 0.027 14.2 0.0 0.067 12.9 0.0 1.6 1 0 0 1 1 1 0 PGAP1-like protein Hpr_kinase_C PF07475.12 KXS95554.1 - 0.13 11.8 0.0 0.71 9.4 0.0 2.1 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_19 PF13245.6 KXS95554.1 - 0.21 11.9 1.0 11 6.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain CENP-F_leu_zip PF10473.9 KXS95554.1 - 0.38 10.8 38.0 0.01 15.8 16.1 2.9 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HSP70 PF00012.20 KXS95555.1 - 0.0055 14.9 0.4 0.012 13.9 0.0 1.6 2 0 0 2 2 2 1 Hsp70 protein DDR PF08841.10 KXS95555.1 - 0.029 13.4 0.1 0.05 12.6 0.1 1.3 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain zf-C2H2_4 PF13894.6 KXS95556.1 - 4.8e-08 33.2 32.2 0.019 15.8 0.4 6.9 7 0 0 7 7 5 3 C2H2-type zinc finger zf-C2H2 PF00096.26 KXS95556.1 - 1e-07 32.0 21.7 0.019 15.4 0.4 6.8 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KXS95556.1 - 2.4e-05 24.5 6.2 0.0011 19.1 1.7 6.4 7 0 0 7 7 7 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXS95556.1 - 0.0057 17.0 0.3 0.0057 17.0 0.3 4.8 4 0 0 4 4 3 1 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 KXS95556.1 - 0.031 14.7 0.3 0.031 14.7 0.3 6.3 7 1 0 7 7 6 0 Zinc-finger double domain zf-C2HC_2 PF13913.6 KXS95556.1 - 0.042 13.8 0.1 0.042 13.8 0.1 3.9 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 KXS95556.1 - 0.093 12.8 0.2 0.093 12.8 0.2 6.0 6 0 0 6 6 5 0 C2H2-type zinc finger zf_UBZ PF18439.1 KXS95556.1 - 0.11 12.2 12.9 0.41 10.3 0.1 4.9 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_15 PF17032.5 KXS95556.1 - 0.76 10.6 14.5 1.8 9.4 1.3 3.6 3 0 0 3 3 3 0 zinc-ribbon family DZR PF12773.7 KXS95556.1 - 0.8 9.8 15.7 6.3 6.9 10.3 3.4 2 1 0 2 2 2 0 Double zinc ribbon Zn-C2H2_12 PF18112.1 KXS95556.1 - 3.7 8.1 11.1 21 5.7 0.0 4.3 4 0 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain Zn-ribbon_8 PF09723.10 KXS95556.1 - 8.3 6.6 14.6 0.16 12.1 1.1 3.7 3 1 0 3 3 3 0 Zinc ribbon domain Ilm1 PF10311.9 KXS95557.1 - 1.8e-56 190.3 2.9 2.1e-56 190.1 2.9 1.0 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 DUF4357 PF14267.6 KXS95557.1 - 0.013 15.4 0.2 0.85 9.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4357) GOLD_2 PF13897.6 KXS95558.1 - 0.41 11.1 1.7 0.99 9.9 1.7 1.6 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking HMGL-like PF00682.19 KXS95560.1 - 3.8e-80 269.2 1.1 5.6e-80 268.7 1.1 1.3 1 0 0 1 1 1 1 HMGL-like Trp_syntA PF00290.20 KXS95560.1 - 0.02 13.7 0.0 2.8 6.7 0.0 2.4 2 0 0 2 2 2 0 Tryptophan synthase alpha chain Peptidase_C47 PF05543.13 KXS95560.1 - 0.04 13.5 0.0 0.22 11.1 0.0 2.1 2 0 0 2 2 2 0 Staphopain peptidase C47 TFIIF_beta_N PF17683.1 KXS95560.1 - 0.21 12.2 1.9 0.37 11.5 1.9 1.3 1 0 0 1 1 1 0 TFIIF, beta subunit N-terminus GMC_oxred_N PF00732.19 KXS95561.1 - 4.4e-61 206.9 0.0 6.1e-61 206.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXS95561.1 - 6.8e-31 107.7 0.7 6.8e-31 107.7 0.7 2.3 3 0 0 3 3 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KXS95561.1 - 4.8e-06 25.9 0.6 0.086 11.9 1.1 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 KXS95561.1 - 2e-05 24.0 0.0 0.16 11.2 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXS95561.1 - 0.00064 18.9 0.5 0.0014 17.7 0.5 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KXS95561.1 - 0.0045 17.2 0.0 0.013 15.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXS95561.1 - 0.0078 15.5 0.0 0.19 10.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXS95561.1 - 0.017 14.4 0.0 0.033 13.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 KXS95561.1 - 0.021 14.2 0.0 2.6 7.3 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase DAO PF01266.24 KXS95561.1 - 0.05 13.2 3.4 0.23 11.0 1.6 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KXS95561.1 - 0.11 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.14 KXS95561.1 - 0.23 10.1 0.4 0.54 8.9 0.2 1.6 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.19 KXS95562.1 - 4.2e-17 62.4 0.1 1.2e-14 54.3 0.1 2.5 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KXS95562.1 - 0.00071 19.7 0.0 0.004 17.4 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 KXS95562.1 - 0.18 10.9 0.0 0.47 9.4 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase ABC2_membrane_2 PF12679.7 KXS95563.1 - 0.13 11.5 6.5 0.11 11.8 5.1 1.5 2 0 0 2 2 2 0 ABC-2 family transporter protein Peptidase_M19 PF01244.21 KXS95564.1 - 5e-99 331.5 0.0 6e-99 331.2 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) DUF4199 PF13858.6 KXS95565.1 - 0.12 12.7 11.3 0.17 12.3 3.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) MIG-14_Wnt-bd PF06664.12 KXS95565.1 - 0.28 10.4 10.4 0.42 9.8 10.4 1.2 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion MARVEL PF01284.23 KXS95565.1 - 0.29 11.2 14.7 0.82 9.7 13.7 1.9 1 1 1 2 2 2 0 Membrane-associating domain DUF4271 PF14093.6 KXS95565.1 - 0.45 10.4 13.2 0.77 9.6 13.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4271) DUF3357 PF11837.8 KXS95565.1 - 1.4 9.4 3.8 1.7 9.1 0.0 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF3357) DUF267 PF03268.14 KXS95565.1 - 1.4 7.7 8.2 0.025 13.5 1.1 1.6 2 1 0 2 2 2 0 Caenorhabditis protein of unknown function, DUF267 DUF2569 PF10754.9 KXS95565.1 - 1.4 9.3 16.0 7.1 7.1 16.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2569) Tetraspanin PF00335.20 KXS95565.1 - 2.1 8.0 13.7 15 5.2 13.8 1.9 1 1 0 1 1 1 0 Tetraspanin family DUF2070 PF09843.9 KXS95565.1 - 4 5.6 13.9 5.2 5.2 13.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF5090 PF17009.5 KXS95565.1 - 7.6 6.4 14.9 6.8 6.6 0.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5090) FA_desaturase PF00487.24 KXS95565.1 - 9.5 6.0 9.6 15 5.4 2.7 2.2 1 1 1 2 2 2 0 Fatty acid desaturase Glyco_hydro_72 PF03198.14 KXS95574.1 - 2.5e-135 450.8 6.8 3.7e-135 450.2 6.8 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 KXS95574.1 - 3.6e-25 88.4 5.0 9.5e-25 87.1 5.0 1.8 1 0 0 1 1 1 1 X8 domain DUF3617 PF12276.8 KXS95574.1 - 0.15 12.4 3.0 0.31 11.3 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3617) DUF3767 PF12597.8 KXS95575.1 - 8.3e-27 93.0 0.2 1.5e-26 92.2 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) DUF4547 PF15080.6 KXS95575.1 - 0.03 14.0 0.2 0.042 13.5 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4547) NUSAP PF16006.5 KXS95575.1 - 0.033 14.0 3.9 0.045 13.5 3.9 1.1 1 0 0 1 1 1 0 Nucleolar and spindle-associated protein Aldolase_II PF00596.21 KXS95576.1 - 8e-42 143.3 0.1 1.1e-41 142.8 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain AMP-binding PF00501.28 KXS95578.1 - 7.5e-67 225.8 0.0 1.1e-66 225.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXS95578.1 - 4.2e-10 40.5 0.0 1.3e-09 38.9 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Hexapep PF00132.24 KXS95578.1 - 5.7e-05 22.7 13.2 0.00012 21.7 0.4 4.5 6 0 0 6 6 6 2 Bacterial transferase hexapeptide (six repeats) PP-binding PF00550.25 KXS95578.1 - 0.00022 21.5 0.0 0.00063 20.1 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep_2 PF14602.6 KXS95578.1 - 0.13 12.1 8.8 0.15 11.8 0.9 3.4 4 0 0 4 4 4 0 Hexapeptide repeat of succinyl-transferase FMO-like PF00743.19 KXS95579.1 - 5.2e-21 74.7 0.0 3.3e-20 72.0 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KXS95579.1 - 4.8e-17 62.1 0.0 1e-12 47.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXS95579.1 - 1.7e-10 40.6 0.0 6.9e-09 35.4 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXS95579.1 - 1.5e-09 37.9 0.0 1.2e-08 35.1 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KXS95579.1 - 3e-08 33.2 0.2 3e-06 26.6 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KXS95579.1 - 8.2e-08 32.4 0.1 0.0093 16.0 0.1 4.1 3 1 0 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.24 KXS95579.1 - 9.4e-05 22.1 0.0 0.82 9.2 0.0 2.9 3 0 0 3 3 3 2 FAD dependent oxidoreductase GIDA PF01134.22 KXS95579.1 - 0.001 18.2 0.0 2 7.4 0.0 2.8 3 0 0 3 3 3 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KXS95579.1 - 0.0031 16.6 0.0 0.0052 15.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KXS95579.1 - 0.0054 16.0 0.2 0.018 14.3 0.0 1.8 3 0 0 3 3 3 1 Thi4 family Shikimate_DH PF01488.20 KXS95579.1 - 0.0084 16.2 0.1 0.46 10.5 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 KXS95579.1 - 0.0095 15.2 0.2 0.046 13.0 0.1 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KXS95579.1 - 0.014 15.9 0.1 1.1 9.8 0.1 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXS95579.1 - 0.027 13.2 0.1 0.45 9.2 0.1 2.6 3 0 0 3 3 3 0 HI0933-like protein p450 PF00067.22 KXS95580.1 - 1.6e-23 83.2 0.0 1.9e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Kelch_4 PF13418.6 KXS95581.1 - 3.9e-17 62.0 1.8 0.00031 20.7 0.1 4.5 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_6 PF13964.6 KXS95581.1 - 5.5e-14 51.9 0.9 0.00065 19.9 0.1 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 KXS95581.1 - 1.2e-13 50.4 3.0 6.5e-05 22.4 0.0 4.7 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.6 KXS95581.1 - 8.1e-13 48.0 6.9 0.0021 18.0 0.1 5.3 5 1 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 KXS95581.1 - 1e-11 44.8 12.3 0.038 14.3 0.0 6.9 8 0 0 8 8 8 4 Galactose oxidase, central domain Kelch_2 PF07646.15 KXS95581.1 - 1.5e-10 40.6 3.8 0.01 15.8 0.1 6.2 5 1 1 6 6 6 2 Kelch motif zf-MYND PF01753.18 KXS95582.1 - 5.7e-09 35.9 11.7 5.7e-09 35.9 11.7 2.2 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.16 KXS95582.1 - 0.11 12.4 10.0 0.26 11.2 10.0 1.7 1 0 0 1 1 1 0 HIT zinc finger zf-C6H2 PF15801.5 KXS95582.1 - 0.37 11.1 9.3 0.92 9.9 9.3 1.7 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Glucan_synthase PF02364.15 KXS95583.1 - 0 1374.4 0.0 0 1373.7 0.0 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 KXS95583.1 - 2.4e-40 137.9 1.0 6.7e-40 136.4 1.0 1.8 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 DUF1744 PF08490.12 KXS95584.1 - 3.3e-147 490.2 0.0 5.8e-147 489.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 KXS95584.1 - 1e-81 274.7 0.0 1.6e-81 274.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 KXS95584.1 - 1.7e-14 53.4 0.5 2.9e-12 46.1 0.2 3.3 3 1 0 3 3 3 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 KXS95584.1 - 1.4e-10 41.2 0.1 3.8e-10 39.8 0.1 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 KXS95584.1 - 4.2e-05 23.6 0.0 0.00015 21.8 0.0 2.0 1 0 0 1 1 1 1 RNase_H superfamily zf-DNA_Pol PF08996.10 KXS95584.1 - 2.3 7.9 5.0 6.2 6.5 5.0 1.6 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger TauD PF02668.16 KXS95585.1 - 4.8e-30 105.3 0.0 8.5e-30 104.4 0.0 1.4 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TSSC4 PF15264.6 KXS95585.1 - 0.0059 16.9 0.1 0.012 15.9 0.1 1.5 1 0 0 1 1 1 1 Tumour suppressing sub-chromosomal transferable candidate 4 SKG6 PF08693.10 KXS95588.1 - 0.0048 16.3 0.1 0.01 15.2 0.1 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Arrestin_N PF00339.29 KXS95589.1 - 1.9e-16 60.5 0.0 9.3e-15 54.9 0.0 2.8 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KXS95589.1 - 4.9e-06 27.0 0.0 0.0022 18.5 0.0 2.6 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain IMUP PF15761.5 KXS95590.1 - 0.005 17.5 12.6 0.005 17.5 12.6 1.9 2 0 0 2 2 2 1 Immortalisation up-regulated protein MAP65_ASE1 PF03999.12 KXS95590.1 - 1.1 7.9 7.2 1.3 7.6 7.2 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) SPX PF03105.19 KXS95590.1 - 1.4 8.7 13.2 1.8 8.4 13.2 1.1 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 KXS95590.1 - 1.7 7.4 8.1 1.8 7.3 8.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4692 PF15763.5 KXS95590.1 - 1.7 9.1 9.1 3.5 8.1 9.1 1.5 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) AF-4 PF05110.13 KXS95590.1 - 1.8 6.5 19.9 2.3 6.2 19.9 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Lin-8 PF03353.15 KXS95590.1 - 2.6 7.5 8.0 4.2 6.8 8.0 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist RAP1 PF07218.11 KXS95590.1 - 3.5 5.8 3.4 4 5.6 3.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SR-25 PF10500.9 KXS95590.1 - 4.3 6.9 27.3 9.8 5.7 27.3 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein GREB1 PF15782.5 KXS95590.1 - 5.8 3.9 10.0 7.2 3.6 10.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer UCH PF00443.29 KXS95591.1 - 1e-24 87.4 0.0 1.5e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KXS95591.1 - 1.7e-09 37.9 0.1 3e-09 37.1 0.1 1.3 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 KXS95591.1 - 0.012 15.2 0.2 0.063 12.9 0.2 2.1 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Mito_fiss_reg PF05308.11 KXS95591.1 - 0.021 14.9 5.4 0.038 14.1 5.4 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator PRIMA1 PF16101.5 KXS95591.1 - 0.096 12.7 7.9 0.2 11.7 7.9 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 KXS95591.1 - 0.47 9.9 7.8 0.75 9.2 7.8 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Iso_dh PF00180.20 KXS95592.1 - 2.7e-84 283.3 0.1 3.1e-84 283.1 0.1 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Acetyltransf_1 PF00583.25 KXS95593.1 - 1.1e-09 38.5 0.0 2.3e-09 37.5 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXS95593.1 - 7.7e-08 32.7 0.0 2e-07 31.3 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXS95593.1 - 4e-07 30.0 0.0 7.3e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXS95593.1 - 1.3e-06 28.3 0.0 2.5e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 KXS95593.1 - 0.00082 19.1 0.0 0.0014 18.3 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KXS95593.1 - 0.0039 17.9 0.0 0.0075 16.9 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KXS95593.1 - 0.0076 16.4 0.0 1.3 9.1 0.0 2.1 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXS95593.1 - 0.15 12.2 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Gpr1_Fun34_YaaH PF01184.19 KXS95596.1 - 1.3e-15 57.6 18.2 1.3e-14 54.3 19.2 1.9 1 1 1 2 2 2 1 GPR1/FUN34/yaaH family CPSase_L_D2 PF02786.17 KXS95597.1 - 4e-80 268.3 0.0 6.4e-80 267.6 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 KXS95597.1 - 1.1e-69 234.2 0.0 1.7e-69 233.5 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 KXS95597.1 - 3.4e-39 133.8 0.1 7.5e-39 132.7 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KXS95597.1 - 1.9e-31 108.4 0.0 6.1e-31 106.7 0.0 1.9 2 0 0 2 2 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 KXS95597.1 - 2.2e-29 102.8 0.0 6.3e-29 101.3 0.0 1.8 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 KXS95597.1 - 3.3e-18 65.3 3.1 6.9e-18 64.3 3.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KXS95597.1 - 1.3e-08 34.5 0.1 3.9e-05 23.4 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 KXS95597.1 - 1.9e-07 30.8 0.0 3.8e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus HlyD_3 PF13437.6 KXS95597.1 - 0.00072 20.2 0.1 3.1 8.6 0.0 3.3 3 0 0 3 3 3 2 HlyD family secretion protein ATP-grasp_3 PF02655.14 KXS95597.1 - 0.00077 19.5 0.0 0.0022 18.1 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain HlyD_D23 PF16576.5 KXS95597.1 - 0.00092 18.5 0.1 0.015 14.5 0.1 2.2 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion GCV_H PF01597.19 KXS95597.1 - 0.008 16.1 0.3 0.024 14.5 0.3 1.8 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 KXS95597.1 - 0.011 15.7 0.4 0.026 14.5 0.4 1.6 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain NQRA PF05896.11 KXS95597.1 - 0.013 15.0 0.2 0.023 14.2 0.2 1.3 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) DUF2118 PF09891.9 KXS95597.1 - 0.016 15.2 0.0 0.063 13.2 0.0 2.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) ATPgrasp_ST PF14397.6 KXS95597.1 - 0.027 13.7 0.0 0.062 12.5 0.0 1.6 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp ATP-grasp_4 PF13535.6 KXS95597.1 - 0.039 13.5 0.0 0.14 11.7 0.0 2.0 2 0 0 2 2 2 0 ATP-grasp domain ATPgrasp_Ter PF15632.6 KXS95597.1 - 0.11 12.2 0.1 0.26 11.0 0.1 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon Cm_res_leader PF08077.11 KXS95598.1 - 0.037 14.1 5.5 90 3.8 0.0 5.3 5 0 0 5 5 5 0 Chloramphenicol resistance gene leader peptide DUF5073 PF16817.5 KXS95598.1 - 0.15 12.1 0.2 1 9.4 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF5073) Ste5 PF11610.8 KXS95600.1 - 0.019 14.8 0.2 0.034 14.0 0.2 1.4 1 0 0 1 1 1 0 Scaffold protein Ste5, Fus3-binding region DSBA PF01323.20 KXS95601.1 - 1.4e-22 80.4 0.0 1.8e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 DSBA-like thioredoxin domain TRP_N PF14558.6 KXS95601.1 - 2.7e-22 79.7 3.1 4.1e-22 79.1 3.1 1.2 1 0 0 1 1 1 1 ML-like domain DOCK_N PF16172.5 KXS95602.1 - 3e-101 339.1 0.0 5e-101 338.3 0.0 1.4 1 0 0 1 1 1 1 DOCK N-terminus DHR-2 PF06920.13 KXS95602.1 - 2.6e-38 132.0 2.8 7.5e-38 130.5 2.8 1.7 1 1 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 KXS95602.1 - 1.2e-32 113.4 0.0 2e-32 112.6 0.0 1.4 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins SH3_9 PF14604.6 KXS95602.1 - 0.0016 18.2 0.0 0.03 14.2 0.0 2.6 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KXS95602.1 - 0.021 14.4 0.0 0.051 13.2 0.0 1.6 1 0 0 1 1 1 0 SH3 domain SH3_2 PF07653.17 KXS95602.1 - 0.1 12.3 0.1 0.44 10.3 0.0 2.2 2 0 0 2 2 2 0 Variant SH3 domain Metallothio_Pro PF02069.16 KXS95603.1 - 0.12 12.6 4.7 0.79 10.0 3.5 2.1 2 0 0 2 2 2 0 Prokaryotic metallothionein Asn_synthase PF00733.21 KXS95604.1 - 5e-17 62.6 0.8 2.1e-07 30.9 0.2 3.2 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 KXS95604.1 - 5.3e-06 26.4 0.0 3.2e-05 23.9 0.0 2.2 2 1 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KXS95604.1 - 9.3e-05 22.6 0.0 0.00017 21.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KXS95604.1 - 0.13 11.7 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Aluminium induced protein Tubulin PF00091.25 KXS95606.1 - 5.2e-66 222.6 0.0 8.7e-66 221.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KXS95606.1 - 1.6e-41 141.4 0.2 3.4e-41 140.3 0.0 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain GDPD PF03009.17 KXS95606.1 - 1.9e-30 106.4 0.1 3.5e-29 102.3 0.1 2.2 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Misat_Tub_SegII PF10644.9 KXS95606.1 - 7.2e-05 23.1 0.0 0.00021 21.6 0.0 1.7 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KXS95606.1 - 0.023 14.4 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain GDPD_2 PF13653.6 KXS95606.1 - 0.048 14.1 0.8 0.15 12.5 0.8 2.0 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family EF1_GNE PF00736.19 KXS95609.1 - 8.4e-33 112.4 1.8 1.6e-32 111.5 1.8 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 KXS95609.1 - 8.2e-14 51.7 9.9 8.2e-14 51.7 9.9 2.1 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C PF00043.25 KXS95609.1 - 0.00062 19.9 1.6 0.0015 18.8 0.1 2.4 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXS95609.1 - 0.001 19.2 0.3 0.0066 16.6 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain MMgT PF10270.9 KXS95610.1 - 4e-31 107.3 0.0 5.6e-31 106.8 0.0 1.2 1 0 0 1 1 1 1 Membrane magnesium transporter MutS_V PF00488.21 KXS95611.1 - 1e-49 169.1 0.1 1.9e-49 168.3 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KXS95611.1 - 3.8e-18 66.4 0.0 6.6e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 KXS95611.1 - 0.0038 17.5 0.0 0.0071 16.7 0.0 1.5 1 0 0 1 1 1 1 MutS family domain IV NAD_binding_5 PF07994.12 KXS95612.1 - 3.9e-144 479.9 0.0 4.6e-144 479.7 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 KXS95612.1 - 2.2e-45 153.4 0.7 4.9e-45 152.3 0.7 1.6 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Ribonuc_P_40 PF08584.11 KXS95613.1 - 9.3e-53 179.3 0.0 1.4e-52 178.8 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit MFS_1 PF07690.16 KXS95614.1 - 3.7e-30 105.1 63.4 1.7e-24 86.4 45.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS95614.1 - 2.5e-05 23.4 40.9 0.00013 21.0 14.6 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter DPM3 PF08285.11 KXS95614.1 - 7.8 6.8 8.0 0.74 10.0 0.2 3.0 3 0 0 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) LOR PF04525.12 KXS95615.1 - 9.5e-24 84.0 0.5 1.2e-23 83.7 0.5 1.1 1 0 0 1 1 1 1 LURP-one-related YabP PF07873.11 KXS95615.1 - 0.005 16.6 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 YabP family DUF5052 PF16475.5 KXS95615.1 - 0.037 13.6 0.1 0.074 12.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5052) Myosin_N PF02736.19 KXS95615.1 - 0.11 12.3 0.3 0.49 10.3 0.0 2.1 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain PGK PF00162.19 KXS95616.1 - 1.2e-148 495.1 2.1 1.7e-148 494.6 2.1 1.2 1 0 0 1 1 1 1 Phosphoglycerate kinase VPS9 PF02204.18 KXS95616.1 - 8.9e-28 96.6 0.0 1.7e-27 95.7 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Mpv17_PMP22 PF04117.12 KXS95616.1 - 1e-16 60.8 0.7 2.3e-16 59.7 0.7 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF5601 PF18151.1 KXS95616.1 - 1.3e-14 54.2 0.1 4.6e-14 52.5 0.1 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) CUE PF02845.16 KXS95616.1 - 1.9e-07 30.7 0.1 1e-06 28.3 0.0 2.1 2 0 0 2 2 2 1 CUE domain Lysine_decarbox PF03641.14 KXS95617.1 - 2.7e-31 108.4 0.1 3.9e-31 107.9 0.1 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 KXS95617.1 - 0.00077 19.1 0.9 0.014 15.0 0.9 2.2 1 1 0 1 1 1 1 SLOG cluster4 family AAA_2 PF07724.14 KXS95618.1 - 3.7e-50 170.4 1.5 3.7e-48 163.9 0.0 2.8 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KXS95618.1 - 1.6e-35 121.1 11.0 2.6e-35 120.5 2.2 2.7 2 0 0 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 KXS95618.1 - 1.3e-27 95.7 0.1 5.1e-27 93.7 0.1 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 KXS95618.1 - 2.1e-20 73.5 0.1 2.4e-10 41.0 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXS95618.1 - 3.5e-13 49.7 0.2 1.3e-08 34.9 0.0 3.1 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXS95618.1 - 5.7e-09 36.6 6.9 0.00028 21.3 0.1 4.2 3 2 2 5 5 4 2 AAA ATPase domain Sigma54_activat PF00158.26 KXS95618.1 - 2.1e-08 34.0 1.1 8.2e-06 25.6 0.1 2.7 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.6 KXS95618.1 - 4.2e-08 33.6 1.6 0.013 15.8 0.0 3.9 3 2 0 3 3 2 2 AAA domain TniB PF05621.11 KXS95618.1 - 3e-06 26.8 0.1 0.062 12.7 0.0 4.4 3 2 1 4 4 3 1 Bacterial TniB protein AAA_7 PF12775.7 KXS95618.1 - 5.2e-06 26.1 0.0 0.027 14.0 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_14 PF13173.6 KXS95618.1 - 6.2e-06 26.3 0.2 0.11 12.5 0.0 2.9 3 0 0 3 3 2 2 AAA domain NACHT PF05729.12 KXS95618.1 - 2.5e-05 24.3 0.1 0.038 13.9 0.0 2.7 2 0 0 2 2 2 1 NACHT domain Mg_chelatase PF01078.21 KXS95618.1 - 3.8e-05 23.2 0.1 0.7 9.2 0.0 3.6 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KXS95618.1 - 4.2e-05 23.3 0.1 0.49 10.1 0.0 3.3 3 0 0 3 3 3 2 IstB-like ATP binding protein ATPase_2 PF01637.18 KXS95618.1 - 4.6e-05 23.4 4.5 1.7 8.5 0.0 4.0 3 1 1 4 4 3 2 ATPase domain predominantly from Archaea AAA_24 PF13479.6 KXS95618.1 - 0.00011 22.0 0.0 0.11 12.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain SRP54 PF00448.22 KXS95618.1 - 0.00039 20.1 0.0 0.046 13.4 0.0 2.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 KXS95618.1 - 0.00053 19.3 0.0 0.51 9.6 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin RNA_helicase PF00910.22 KXS95618.1 - 0.00087 19.7 0.1 0.67 10.4 0.0 2.9 2 1 0 2 2 2 1 RNA helicase Roc PF08477.13 KXS95618.1 - 0.00092 19.4 0.1 0.77 10.0 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KXS95618.1 - 0.001 19.0 0.1 2.2 8.2 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase TsaE PF02367.17 KXS95618.1 - 0.0013 18.8 0.1 2.4 8.2 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 KXS95618.1 - 0.0025 18.4 0.8 1.6 9.3 0.0 3.4 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 KXS95618.1 - 0.003 18.1 3.1 1.1 9.7 0.0 3.4 3 0 0 3 3 3 1 ABC transporter AAA_30 PF13604.6 KXS95618.1 - 0.0035 17.1 1.9 0.15 11.7 0.0 3.6 4 0 0 4 4 3 1 AAA domain AAA_28 PF13521.6 KXS95618.1 - 0.0039 17.5 2.3 1.6 9.0 0.0 3.9 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.6 KXS95618.1 - 0.0056 17.0 0.4 0.38 11.1 0.0 3.3 2 1 0 3 3 3 1 AAA domain PduV-EutP PF10662.9 KXS95618.1 - 0.01 15.5 1.3 0.52 10.0 0.0 3.0 4 0 0 4 4 2 0 Ethanolamine utilisation - propanediol utilisation ResIII PF04851.15 KXS95618.1 - 0.013 15.5 0.0 4.7 7.2 0.0 3.2 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit DUF815 PF05673.13 KXS95618.1 - 0.013 14.7 1.0 1.2 8.2 0.1 3.4 3 2 0 3 3 3 0 Protein of unknown function (DUF815) PhoH PF02562.16 KXS95618.1 - 0.039 13.4 0.0 1.1 8.7 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein ATP_bind_1 PF03029.17 KXS95618.1 - 0.041 13.7 0.0 0.65 9.7 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 KXS95618.1 - 0.048 13.6 1.1 0.9 9.4 0.0 2.9 3 0 0 3 3 2 0 NTPase AAA_25 PF13481.6 KXS95618.1 - 0.053 13.1 0.1 1 8.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KXS95618.1 - 0.072 13.2 0.1 19 5.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KXS95618.1 - 0.084 12.6 0.0 5.4 6.8 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain PIF1 PF05970.14 KXS95618.1 - 0.084 12.0 0.1 32 3.5 0.0 3.0 3 0 0 3 3 3 0 PIF1-like helicase AAA_21 PF13304.6 KXS95618.1 - 0.096 12.5 1.1 2.5 7.8 0.1 3.2 4 0 0 4 4 3 0 AAA domain, putative AbiEii toxin, Type IV TA system RuvB_N PF05496.12 KXS95618.1 - 0.11 12.2 1.0 8.2 6.2 0.0 3.4 3 1 0 3 3 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_6 PF12774.7 KXS95618.1 - 0.2 10.6 0.0 3.5 6.5 0.0 2.3 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region Ribosomal_L9_C PF03948.14 KXS95618.1 - 0.72 10.4 0.0 0.72 10.4 0.0 2.6 3 0 0 3 3 1 0 Ribosomal protein L9, C-terminal domain DUF1640 PF07798.11 KXS95618.1 - 1.4 8.9 9.6 2.7 8.0 9.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) DUF87 PF01935.17 KXS95618.1 - 1.6 8.8 6.5 31 4.6 0.0 3.4 3 0 0 3 3 3 0 Helicase HerA, central domain OEP PF02321.18 KXS95618.1 - 2.4 7.9 13.0 5.4 6.8 13.0 1.5 1 0 0 1 1 1 0 Outer membrane efflux protein DUF4094 PF13334.6 KXS95618.1 - 5 7.6 7.0 0.72 10.3 0.6 2.8 3 0 0 3 3 2 0 Domain of unknown function (DUF4094) Seryl_tRNA_N PF02403.22 KXS95618.1 - 5.9 7.2 15.8 14 5.9 12.7 3.0 2 1 0 2 2 1 0 Seryl-tRNA synthetase N-terminal domain DUF4407 PF14362.6 KXS95618.1 - 6.7 6.0 10.3 11 5.2 10.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DSS1_SEM1 PF05160.13 KXS95619.1 - 2.3e-23 82.0 16.3 3.1e-23 81.6 16.3 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family Ig_mannosidase PF17753.1 KXS95620.1 - 3.3e-21 74.8 0.3 8.8e-21 73.5 0.3 1.7 1 0 0 1 1 1 1 Ig-fold domain Mannosidase_ig PF17786.1 KXS95620.1 - 2.3e-20 73.0 0.5 6.2e-20 71.6 0.1 2.1 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KXS95620.1 - 4.5e-06 27.3 0.0 2.1e-05 25.1 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 DUF2613 PF11021.8 KXS95621.1 - 0.011 15.8 0.3 0.032 14.3 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) DUF4690 PF15756.5 KXS95621.1 - 0.083 13.5 0.1 0.2 12.3 0.1 1.6 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Glycophorin_A PF01102.18 KXS95621.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Glycophorin A EphA2_TM PF14575.6 KXS95621.1 - 0.17 12.7 0.0 0.4 11.6 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF202 PF02656.15 KXS95621.1 - 0.17 12.3 2.0 1.2 9.6 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Nitrate_red_gam PF02665.14 KXS95621.1 - 0.42 10.1 1.8 0.33 10.5 0.2 1.6 2 0 0 2 2 2 0 Nitrate reductase gamma subunit PEARLI-4 PF05278.12 KXS95622.1 - 0.026 14.1 0.1 0.041 13.5 0.1 1.3 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) PEARLI-4 PF05278.12 KXS95624.1 - 0.026 14.1 0.1 0.041 13.5 0.1 1.3 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) tRNA-synt_2 PF00152.20 KXS95626.1 - 2e-89 299.8 0.0 2.7e-89 299.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KXS95626.1 - 0.0022 17.9 0.0 0.0056 16.6 0.0 1.7 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KXS95626.1 - 0.011 15.3 0.2 0.028 13.9 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.25 KXS95626.1 - 0.082 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) NAD_binding_6 PF08030.12 KXS95627.1 - 1.7e-17 64.0 0.0 2.5e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KXS95627.1 - 3.5e-17 62.7 8.5 3.5e-17 62.7 8.5 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KXS95627.1 - 3.5e-10 39.9 0.0 1.9e-09 37.6 0.0 2.2 1 1 0 1 1 1 1 FAD-binding domain FAD_binding_6 PF00970.24 KXS95627.1 - 0.0029 17.9 0.0 0.0053 17.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KXS95627.1 - 0.11 13.2 0.0 37 5.0 0.0 2.9 3 0 0 3 3 3 0 Oxidoreductase NAD-binding domain Sensor PF13796.6 KXS95627.1 - 0.12 12.4 9.6 0.061 13.4 1.4 2.6 2 0 0 2 2 2 0 Putative sensor Ank_2 PF12796.7 KXS95629.1 - 1e-14 54.8 0.0 4.2e-11 43.3 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS95629.1 - 8.9e-12 45.3 0.0 0.0023 18.4 0.0 3.8 2 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS95629.1 - 1e-10 41.6 0.7 2.4e-05 24.5 0.1 4.9 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS95629.1 - 7.9e-07 28.9 0.0 0.0088 16.5 0.0 4.3 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 KXS95629.1 - 0.00037 20.8 0.3 0.61 10.6 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeat Rick_17kDa_Anti PF05433.15 KXS95630.1 - 0.025 14.4 4.4 0.025 14.4 4.4 2.3 2 0 0 2 2 2 0 Glycine zipper 2TM domain CDC45 PF02724.14 KXS95630.1 - 0.31 9.3 14.8 0.033 12.5 0.7 2.0 2 0 0 2 2 2 0 CDC45-like protein Aldedh PF00171.22 KXS95631.1 - 9.6e-184 611.2 0.2 1.1e-183 611.0 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KXS95631.1 - 0.088 12.2 0.0 0.41 10.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Stb3 PF10330.9 KXS95632.1 - 4.3e-31 106.8 0.0 9.2e-31 105.7 0.0 1.5 1 0 0 1 1 1 1 Putative Sin3 binding protein Cwf_Cwc_15 PF04889.12 KXS95632.1 - 1.1 9.0 4.7 1.7 8.3 4.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein HEAT PF02985.22 KXS95633.1 - 5.7e-40 131.9 22.5 0.019 15.2 0.1 13.4 14 0 0 14 14 14 11 HEAT repeat HEAT_2 PF13646.6 KXS95633.1 - 1.1e-37 128.3 8.3 3e-11 43.5 0.0 8.5 4 3 6 10 10 10 9 HEAT repeats HEAT_EZ PF13513.6 KXS95633.1 - 7.3e-15 55.1 13.2 0.021 15.3 0.0 9.4 7 3 3 10 10 10 3 HEAT-like repeat Cnd1 PF12717.7 KXS95633.1 - 2.9e-14 53.4 6.3 0.0026 17.8 0.1 6.7 6 1 1 7 7 7 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KXS95633.1 - 5e-11 43.1 1.4 0.0022 18.5 0.1 7.0 6 2 3 9 9 8 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 KXS95633.1 - 9.8e-08 31.0 5.7 3.6e-05 22.5 0.9 5.0 3 1 1 4 4 4 2 Adaptin N terminal region RTP1_C1 PF10363.9 KXS95633.1 - 3.7e-07 30.3 3.2 0.57 10.4 0.1 4.7 4 1 0 4 4 4 3 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 KXS95633.1 - 1.4e-05 24.8 1.3 1.4 8.4 0.0 5.0 3 2 1 5 5 5 1 CLASP N terminal Arm PF00514.23 KXS95633.1 - 0.00032 20.6 5.1 3.2 7.9 0.0 5.7 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat Ecm29 PF13001.7 KXS95633.1 - 0.021 13.5 3.5 1 8.0 0.1 3.8 4 1 1 5 5 5 0 Proteasome stabiliser IFRD PF05004.13 KXS95633.1 - 0.027 13.6 0.5 1.6 7.8 0.0 3.6 3 1 2 5 5 5 0 Interferon-related developmental regulator (IFRD) TetR_C_16 PF17920.1 KXS95633.1 - 0.033 14.4 1.2 30 4.9 0.0 4.5 3 1 1 4 4 4 0 Tetracyclin repressor-like, C-terminal domain Proteasom_PSMB PF10508.9 KXS95633.1 - 0.088 11.3 2.0 0.71 8.3 0.0 2.5 2 1 0 2 2 2 0 Proteasome non-ATPase 26S subunit M11L PF11099.8 KXS95633.1 - 0.096 13.0 0.1 4.8 7.4 0.0 3.2 2 1 1 3 3 3 0 Apoptosis regulator M11L like API5 PF05918.11 KXS95633.1 - 0.91 8.3 4.2 6.6 5.4 0.1 3.6 3 2 1 4 4 4 0 Apoptosis inhibitory protein 5 (API5) NAD_binding_10 PF13460.6 KXS95634.1 - 3.1e-05 23.9 0.0 4.3e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KXS95634.1 - 0.00034 20.1 0.0 0.00084 18.8 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KXS95634.1 - 0.0046 16.5 0.0 0.82 9.2 0.0 2.1 2 0 0 2 2 2 2 NmrA-like family Epimerase PF01370.21 KXS95634.1 - 0.022 14.2 0.0 0.075 12.5 0.0 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KXS95634.1 - 0.044 12.9 0.0 0.068 12.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Methyltransf_11 PF08241.12 KXS95635.1 - 1.2e-10 41.9 0.0 2.7e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXS95635.1 - 1.2e-10 41.4 0.0 1.9e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS95635.1 - 1.9e-08 34.9 0.0 4.3e-08 33.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS95635.1 - 1.4e-07 32.2 0.0 2.6e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS95635.1 - 6.1e-05 22.9 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXS95635.1 - 0.0014 18.1 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family RGS PF00615.19 KXS95636.1 - 1.8e-08 34.7 0.0 8.7e-06 26.0 0.0 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain Fibrillarin PF01269.17 KXS95636.1 - 0.19 10.8 0.0 0.35 10.0 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin PHD PF00628.29 KXS95637.1 - 6e-12 45.3 5.5 1.4e-11 44.1 5.5 1.7 1 0 0 1 1 1 1 PHD-finger zf-CpG_bind_C PF12269.8 KXS95637.1 - 0.002 17.9 1.3 0.0054 16.5 0.2 2.1 2 0 0 2 2 2 1 CpG binding protein zinc finger C terminal domain Hanta_G1 PF01567.16 KXS95637.1 - 0.38 9.4 0.7 0.55 8.9 0.7 1.1 1 0 0 1 1 1 0 Hantavirus glycoprotein G1 tRNA_synthFbeta PF17759.1 KXS95638.1 - 4.1e-40 137.5 0.0 5.9e-40 137.0 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 KXS95638.1 - 2.9e-29 101.1 0.2 5.4e-28 97.0 0.0 2.3 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 KXS95638.1 - 4.1e-21 75.4 0.1 6.9e-21 74.7 0.1 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 KXS95638.1 - 2.9e-15 56.3 0.0 1.8e-12 47.4 0.0 2.8 3 0 0 3 3 3 2 tRNA synthetase B5 domain tRNA-synt_2d PF01409.20 KXS95638.1 - 0.071 12.6 0.0 4.3 6.7 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Ribosomal_S7e PF01251.18 KXS95639.1 - 3e-80 268.3 0.0 3.7e-80 268.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Steroid_dh PF02544.16 KXS95640.1 - 1.2e-13 51.3 2.1 2.5e-13 50.3 2.1 1.6 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KXS95640.1 - 6.2e-06 25.9 4.4 1.1e-05 25.0 2.1 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1295) Pkinase PF00069.25 KXS95641.1 - 4.4e-58 196.7 0.0 6.4e-58 196.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS95641.1 - 1.4e-19 70.4 0.0 2.3e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS95641.1 - 3e-06 26.8 0.0 5.8e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXS95641.1 - 1.2e-05 25.3 1.0 0.13 12.2 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KXS95641.1 - 0.00012 21.5 0.2 0.00023 20.6 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KXS95641.1 - 0.0011 17.8 0.0 0.0018 17.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KXS95641.1 - 0.01 15.5 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 KXS95641.1 - 0.015 14.3 0.0 0.025 13.5 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain DUF1295 PF06966.12 KXS95642.1 - 2e-40 138.8 10.2 2.7e-40 138.4 10.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DUF2517 PF10725.9 KXS95642.1 - 0.017 14.9 0.0 0.059 13.1 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2517) ICMT PF04140.14 KXS95642.1 - 0.033 14.6 0.5 0.13 12.7 0.0 2.2 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ACP53EA PF06313.11 KXS95642.1 - 0.18 12.1 0.1 3.4 7.9 0.0 2.6 3 0 0 3 3 3 0 Drosophila ACP53EA protein Beta-lactamase PF00144.24 KXS95662.1 - 6.6e-40 137.3 0.0 8.6e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase MIP PF00230.20 KXS95663.1 - 2e-46 158.5 12.5 3e-46 158.0 12.5 1.2 1 0 0 1 1 1 1 Major intrinsic protein Response_reg PF00072.24 KXS95663.1 - 3.7e-19 68.9 0.0 3.1e-13 49.9 0.0 2.3 2 0 0 2 2 2 2 Response regulator receiver domain DGF-1_C PF11040.8 KXS95663.1 - 8 6.5 10.7 0.12 12.4 1.9 2.6 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus COesterase PF00135.28 KXS95664.1 - 3.6e-54 184.5 0.0 8.4e-54 183.3 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXS95664.1 - 0.054 13.4 0.4 0.24 11.2 0.4 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold Cyclin_N PF00134.23 KXS95665.1 - 5.5e-14 52.0 0.0 1.1e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KXS95665.1 - 2.4e-07 31.3 0.0 5.6e-06 26.8 0.0 2.3 2 0 0 2 2 2 1 Cyclin Ecl1 PF12855.7 KXS95666.1 - 5.9e-35 122.0 21.9 5.9e-35 122.0 21.9 2.8 3 0 0 3 3 3 1 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 KXS95666.1 - 0.0024 17.9 0.3 0.0057 16.7 0.3 1.6 1 0 0 1 1 1 1 MYND finger RIG-I_C PF18119.1 KXS95666.1 - 0.12 12.4 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 RIG-I receptor C-terminal domain zf-FLZ PF04570.14 KXS95666.1 - 0.18 11.3 4.9 1.2 8.7 4.9 2.1 1 1 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 DUF2256 PF10013.9 KXS95666.1 - 0.65 10.2 4.1 0.6 10.3 0.5 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) Ecl1 PF12855.7 KXS95667.1 - 5.9e-35 122.0 21.9 5.9e-35 122.0 21.9 2.8 3 0 0 3 3 3 1 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 KXS95667.1 - 0.0024 17.9 0.3 0.0057 16.7 0.3 1.6 1 0 0 1 1 1 1 MYND finger RIG-I_C PF18119.1 KXS95667.1 - 0.12 12.4 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 RIG-I receptor C-terminal domain zf-FLZ PF04570.14 KXS95667.1 - 0.18 11.3 4.9 1.2 8.7 4.9 2.1 1 1 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 DUF2256 PF10013.9 KXS95667.1 - 0.65 10.2 4.1 0.6 10.3 0.5 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) Ecl1 PF12855.7 KXS95668.1 - 2.1e-27 97.4 22.2 2.1e-27 97.4 22.2 2.9 3 0 0 3 3 3 1 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 KXS95668.1 - 0.045 13.8 0.2 0.11 12.6 0.2 1.6 1 0 0 1 1 1 0 MYND finger Ecl1 PF12855.7 KXS95669.1 - 5.9e-35 122.0 21.9 5.9e-35 122.0 21.9 2.8 3 0 0 3 3 3 1 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 KXS95669.1 - 0.0024 17.9 0.3 0.0057 16.7 0.3 1.6 1 0 0 1 1 1 1 MYND finger RIG-I_C PF18119.1 KXS95669.1 - 0.12 12.4 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 RIG-I receptor C-terminal domain zf-FLZ PF04570.14 KXS95669.1 - 0.18 11.3 4.9 1.2 8.7 4.9 2.1 1 1 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 DUF2256 PF10013.9 KXS95669.1 - 0.65 10.2 4.1 0.6 10.3 0.5 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) Ecl1 PF12855.7 KXS95670.1 - 5.9e-35 122.0 21.9 5.9e-35 122.0 21.9 2.8 3 0 0 3 3 3 1 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 KXS95670.1 - 0.0024 17.9 0.3 0.0057 16.7 0.3 1.6 1 0 0 1 1 1 1 MYND finger RIG-I_C PF18119.1 KXS95670.1 - 0.12 12.4 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 RIG-I receptor C-terminal domain zf-FLZ PF04570.14 KXS95670.1 - 0.18 11.3 4.9 1.2 8.7 4.9 2.1 1 1 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 DUF2256 PF10013.9 KXS95670.1 - 0.65 10.2 4.1 0.6 10.3 0.5 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) Ecl1 PF12855.7 KXS95671.1 - 2.1e-27 97.4 22.2 2.1e-27 97.4 22.2 2.9 3 0 0 3 3 3 1 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 KXS95671.1 - 0.045 13.8 0.2 0.11 12.6 0.2 1.6 1 0 0 1 1 1 0 MYND finger ketoacyl-synt PF00109.26 KXS95672.1 - 9.4e-58 195.8 3.8 2.6e-57 194.3 0.6 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KXS95672.1 - 3.4e-36 123.8 2.1 8.1e-36 122.6 0.8 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 KXS95672.1 - 3.8e-06 26.4 1.2 0.00022 20.7 0.1 2.2 2 0 0 2 2 2 2 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXS95672.1 - 0.0079 15.8 3.2 0.11 12.1 0.8 3.0 3 1 0 3 3 3 1 Thiolase, C-terminal domain KAsynt_C_assoc PF16197.5 KXS95672.1 - 0.12 12.8 0.0 0.4 11.1 0.0 1.8 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension ACP_syn_III PF08545.10 KXS95672.1 - 0.22 11.4 3.2 3.9 7.4 0.0 3.4 4 0 0 4 4 4 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Snf7 PF03357.21 KXS95673.1 - 2.4e-47 160.7 12.8 2.7e-47 160.6 12.8 1.1 1 0 0 1 1 1 1 Snf7 DUF3584 PF12128.8 KXS95673.1 - 0.0016 16.1 8.9 0.0019 15.8 8.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) CLZ PF16526.5 KXS95673.1 - 0.04 14.3 0.0 0.04 14.3 0.0 3.5 4 1 1 5 5 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Ncstrn_small PF18266.1 KXS95673.1 - 0.072 13.1 0.6 0.1 12.6 0.6 1.2 1 0 0 1 1 1 0 Nicastrin small lobe Exonuc_VII_L PF02601.15 KXS95673.1 - 0.11 12.0 4.7 0.14 11.7 4.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit FliJ PF02050.16 KXS95673.1 - 0.12 12.6 12.7 0.27 11.5 12.7 1.6 1 0 0 1 1 1 0 Flagellar FliJ protein Atg14 PF10186.9 KXS95673.1 - 0.16 11.0 6.2 0.26 10.3 6.2 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Endotoxin_N PF03945.14 KXS95673.1 - 0.29 10.8 6.5 0.81 9.4 0.5 2.1 1 1 1 2 2 2 0 delta endotoxin, N-terminal domain DASH_Spc19 PF08287.11 KXS95673.1 - 0.35 10.8 8.8 2 8.3 8.5 2.1 1 1 0 1 1 1 0 Spc19 PEP-utilisers_N PF05524.13 KXS95673.1 - 0.38 10.9 4.9 1.3 9.2 0.4 2.3 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal NPV_P10 PF05531.12 KXS95673.1 - 0.48 10.9 8.3 4.2 7.9 1.7 3.1 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 KXS95673.1 - 1.5 9.3 12.0 2.2 8.7 0.3 3.7 1 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF2120 PF09893.9 KXS95673.1 - 1.8 8.7 6.8 1 9.5 4.2 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) DUF848 PF05852.11 KXS95673.1 - 2.1 8.4 7.5 2.2 8.4 5.5 2.1 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) CorA PF01544.18 KXS95673.1 - 5.2 6.3 7.7 5.4 6.3 3.3 2.1 1 1 0 2 2 2 0 CorA-like Mg2+ transporter protein Uso1_p115_C PF04871.13 KXS95673.1 - 6.7 7.1 21.5 98 3.3 21.5 2.6 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Ank_2 PF12796.7 KXS95674.1 - 8.7e-37 125.6 0.2 7.4e-11 42.5 0.1 5.1 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS95674.1 - 1.3e-29 102.2 5.0 8.8e-07 29.4 0.0 7.4 2 2 6 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 KXS95674.1 - 2.3e-29 100.5 12.0 0.00046 20.5 0.1 8.7 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 KXS95674.1 - 1.4e-25 89.0 8.1 3.9e-05 23.8 0.1 6.1 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS95674.1 - 2.8e-23 79.5 0.1 0.0052 17.2 0.0 7.9 7 0 0 7 7 7 5 Ankyrin repeat SesA PF17107.5 KXS95674.1 - 0.048 13.8 1.8 0.2 11.8 1.8 2.1 1 1 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Gp37 PF09646.10 KXS95674.1 - 0.086 12.7 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Gp37 protein Apolipoprotein PF01442.18 KXS95674.1 - 3.7 7.4 7.2 2.7 7.8 3.6 2.1 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain OPT PF03169.15 KXS95676.1 - 7.9e-148 493.8 47.4 7.9e-148 493.8 47.4 1.9 3 0 0 3 3 3 1 OPT oligopeptide transporter protein DUF1295 PF06966.12 KXS95676.1 - 3.6e-39 134.7 6.1 5.6e-39 134.1 0.4 3.2 2 1 0 2 2 2 1 Protein of unknown function (DUF1295) RRM_1 PF00076.22 KXS95677.1 - 1.3e-78 258.7 6.3 3.1e-19 68.6 0.3 5.6 5 1 1 6 6 6 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 KXS95677.1 - 1.8e-28 98.5 1.8 2.7e-28 97.9 0.4 2.2 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 KXS95677.1 - 1.9e-09 37.2 0.2 0.0042 16.7 0.0 4.7 2 1 3 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXS95677.1 - 1.3e-07 31.4 0.1 0.005 16.7 0.0 3.8 3 0 0 3 3 3 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KXS95677.1 - 6.7e-05 22.8 0.7 3.5 7.7 0.1 4.2 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KXS95677.1 - 0.0019 18.2 13.2 0.5 10.5 4.4 4.8 4 2 2 6 6 6 2 RNA binding motif RRM_7 PF16367.5 KXS95677.1 - 0.0039 17.3 0.1 5.6 7.2 0.0 4.7 5 1 0 5 5 5 1 RNA recognition motif YflT PF11181.8 KXS95677.1 - 0.0093 16.5 9.7 0.14 12.7 0.6 3.6 4 0 0 4 4 4 2 Heat induced stress protein YflT CbiG_mid PF11761.8 KXS95677.1 - 0.017 15.2 0.0 13 6.0 0.0 3.4 2 1 1 3 3 3 0 Cobalamin biosynthesis central region Limkain-b1 PF11608.8 KXS95677.1 - 0.068 13.2 0.4 3.7 7.7 0.0 3.2 3 0 0 3 3 3 0 Limkain b1 OB_RNB PF08206.11 KXS95677.1 - 0.12 12.0 2.6 13 5.5 0.0 3.4 3 0 0 3 3 3 0 Ribonuclease B OB domain Pup PF05639.11 KXS95677.1 - 6.6 7.7 12.3 24 5.9 0.7 3.1 2 0 0 2 2 2 0 Pup-like protein Far-17a_AIG1 PF04750.14 KXS95678.1 - 3.2e-50 170.3 8.3 4.2e-50 169.9 8.3 1.1 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein 2C_adapt PF08793.10 KXS95679.1 - 0.14 12.3 0.2 0.42 10.8 0.0 1.9 2 0 0 2 2 2 0 2-cysteine adaptor domain Myb_DNA-binding PF00249.31 KXS95680.1 - 0.0092 16.2 0.1 0.025 14.8 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain NUDE_C PF04880.13 KXS95680.1 - 0.038 14.5 0.7 0.038 14.5 0.7 4.0 4 1 0 4 4 4 0 NUDE protein, C-terminal conserved region GcrA PF07750.11 KXS95680.1 - 0.063 13.7 1.1 0.2 12.1 0.0 2.3 2 0 0 2 2 2 0 GcrA cell cycle regulator HTH_32 PF13565.6 KXS95680.1 - 0.42 11.2 3.6 18 6.1 0.0 3.5 2 1 0 2 2 2 0 Homeodomain-like domain Roughex PF06020.11 KXS95680.1 - 7.4 5.6 13.1 5.8 5.9 10.7 2.1 2 0 0 2 2 2 0 Drosophila roughex protein Amidase PF01425.21 KXS95681.1 - 3.1e-93 313.2 0.0 2.6e-92 310.1 0.0 1.9 1 1 0 1 1 1 1 Amidase MFS_1 PF07690.16 KXS95682.1 - 4.7e-25 88.3 28.1 5.3e-25 88.1 24.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS95683.1 - 3.7e-92 309.5 22.5 4.6e-92 309.3 22.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS95683.1 - 5e-26 91.5 22.2 7.3e-26 90.9 18.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXS95683.1 - 2.2e-08 33.0 2.5 2.2e-08 33.0 2.5 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 KXS95683.1 - 0.18 10.6 17.1 0.1 11.4 6.0 2.3 2 0 0 2 2 2 0 MFS_1 like family PTR2 PF00854.21 KXS95683.1 - 0.33 9.7 12.4 0.79 8.5 1.2 2.6 2 1 0 2 2 2 0 POT family Mnd1 PF03962.15 KXS95684.1 - 1.9e-23 82.5 0.2 8.7e-23 80.4 0.1 2.1 2 0 0 2 2 2 1 Mnd1 HTH domain LZ3wCH PF18517.1 KXS95684.1 - 0.032 14.3 0.1 0.25 11.4 0.1 2.3 2 0 0 2 2 2 0 Leucine zipper with capping helix domain Adeno_E1B_19K PF01691.16 KXS95684.1 - 0.058 12.9 0.0 0.098 12.2 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E1B 19K protein / small t-antigen Cortex-I_coil PF09304.10 KXS95684.1 - 0.087 13.0 4.2 1 9.6 0.4 2.6 1 1 1 2 2 2 0 Cortexillin I, coiled coil DUF2362 PF10154.9 KXS95684.1 - 0.088 11.7 2.2 0.12 11.3 2.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) CSN5_C PF18323.1 KXS95684.1 - 0.12 13.3 5.2 0.28 12.1 2.4 2.5 1 1 1 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain Cnn_1N PF07989.11 KXS95684.1 - 1.1 9.5 5.0 0.37 11.0 0.5 2.6 3 1 1 4 4 4 0 Centrosomin N-terminal motif 1 OmpH PF03938.14 KXS95684.1 - 2.2 8.6 7.8 1.1 9.6 5.7 1.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) RRM_1 PF00076.22 KXS95685.1 - 4.1e-28 97.0 0.1 2.5e-17 62.4 0.0 4.2 3 2 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KXS95685.1 - 0.0012 18.9 0.2 0.1 12.7 0.1 3.5 2 2 0 2 2 2 1 Limkain b1 DbpA PF03880.15 KXS95685.1 - 0.063 13.3 0.0 0.42 10.6 0.0 2.4 3 0 0 3 3 3 0 DbpA RNA binding domain RRM_occluded PF16842.5 KXS95685.1 - 0.082 12.8 0.0 0.29 11.0 0.0 1.9 1 0 0 1 1 1 0 Occluded RNA-recognition motif LRR_8 PF13855.6 KXS95687.1 - 3.9e-11 42.5 2.2 2e-10 40.3 2.4 2.1 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 KXS95687.1 - 2.9e-09 37.1 4.6 1.3e-07 31.8 0.3 3.8 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXS95687.1 - 0.012 16.0 4.0 2 9.3 1.2 4.1 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 KXS95687.1 - 0.015 15.3 2.1 1.4 9.1 0.0 3.6 3 0 0 3 3 3 0 Leucine Rich repeat Glyco_hydro_35 PF01301.19 KXS95688.1 - 2.3e-86 290.3 0.0 3.2e-86 289.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 KXS95688.1 - 3.7e-57 193.1 1.0 5.7e-57 192.5 1.0 1.2 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 KXS95688.1 - 2.8e-48 163.2 3.0 3.4e-28 98.5 0.0 3.2 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 KXS95688.1 - 1.1e-16 60.1 0.0 2.2e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Glyco_hydro_35 PF01301.19 KXS95689.1 - 5.5e-90 302.2 0.0 7.9e-90 301.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 KXS95689.1 - 3.7e-57 193.1 1.0 5.6e-57 192.5 1.0 1.2 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 KXS95689.1 - 2.7e-48 163.3 3.0 3.4e-28 98.5 0.0 3.2 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 KXS95689.1 - 1.1e-16 60.1 0.0 2.2e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Glyco_hydro_35 PF01301.19 KXS95690.1 - 2.5e-86 290.2 0.0 3.6e-86 289.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 KXS95690.1 - 3.9e-57 193.0 1.0 6.1e-57 192.4 1.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 KXS95690.1 - 3.7e-48 162.8 3.2 3.6e-28 98.4 0.0 3.2 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 KXS95690.1 - 1.2e-16 60.0 0.0 2.4e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Glyco_hydro_35 PF01301.19 KXS95691.1 - 2.3e-86 290.3 0.0 3.2e-86 289.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 KXS95691.1 - 3.7e-57 193.1 1.0 5.7e-57 192.5 1.0 1.2 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 KXS95691.1 - 2.8e-48 163.2 3.0 3.4e-28 98.5 0.0 3.2 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 KXS95691.1 - 1.1e-16 60.1 0.0 2.2e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Glyco_hydro_35 PF01301.19 KXS95692.1 - 5.5e-90 302.2 0.0 7.9e-90 301.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 KXS95692.1 - 3.7e-57 193.1 1.0 5.6e-57 192.5 1.0 1.2 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 KXS95692.1 - 2.7e-48 163.3 3.0 3.4e-28 98.5 0.0 3.2 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 KXS95692.1 - 1.1e-16 60.1 0.0 2.2e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 NnrU PF07298.11 KXS95693.1 - 0.2 11.1 7.6 0.33 10.4 7.6 1.3 1 0 0 1 1 1 0 NnrU protein NnrU PF07298.11 KXS95694.1 - 0.2 11.1 7.6 0.33 10.4 7.6 1.3 1 0 0 1 1 1 0 NnrU protein Glyco_hydro_35 PF01301.19 KXS95695.1 - 2.5e-86 290.2 0.0 3.6e-86 289.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 KXS95695.1 - 3.9e-57 193.0 1.0 6.1e-57 192.4 1.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 KXS95695.1 - 3.7e-48 162.8 3.2 3.6e-28 98.4 0.0 3.2 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 KXS95695.1 - 1.2e-16 60.0 0.0 2.4e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 WD40 PF00400.32 KXS95698.1 - 1.6e-16 60.3 14.4 4.1e-05 24.3 1.0 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS95698.1 - 1.4e-11 44.5 0.3 0.014 15.7 0.0 5.4 4 2 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Glyco_transf_8 PF01501.20 KXS95699.1 - 0.0015 18.1 0.2 1.4 8.4 0.0 2.8 2 1 0 2 2 2 2 Glycosyl transferase family 8 Fungal_trans_2 PF11951.8 KXS95700.1 - 5.3e-63 213.1 0.0 7.6e-63 212.6 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS95700.1 - 3.4e-10 39.9 6.7 5.9e-10 39.1 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RXT2_N PF08595.11 KXS95701.1 - 5.8e-38 130.4 0.0 1.5e-37 129.0 0.0 1.8 1 0 0 1 1 1 1 RXT2-like, N-terminal FCD PF07729.12 KXS95702.1 - 0.039 14.4 0.5 0.33 11.4 0.0 2.6 3 0 0 3 3 3 0 FCD domain SRP40_C PF05022.12 KXS95703.1 - 8.5e-17 61.8 1.4 1.6e-14 54.5 0.7 2.8 2 0 0 2 2 2 2 SRP40, C-terminal domain MRP-L46 PF11788.8 KXS95704.1 - 8.2e-28 97.5 0.0 2.6e-27 95.9 0.0 1.9 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.28 KXS95704.1 - 0.068 13.2 0.2 0.16 12.1 0.2 1.6 1 1 0 1 1 1 0 NUDIX domain SRP_TPR_like PF17004.5 KXS95705.1 - 4.9e-18 65.2 0.4 1.2e-16 60.8 0.4 2.4 2 0 0 2 2 2 1 Putative TPR-like repeat SRP72 PF08492.12 KXS95705.1 - 1.2e-15 57.6 11.5 1.2e-15 57.6 11.5 2.8 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_19 PF14559.6 KXS95705.1 - 0.00027 21.4 19.3 0.021 15.3 1.3 5.9 4 2 1 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KXS95705.1 - 0.0014 18.8 3.5 3 8.1 0.2 4.4 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KXS95705.1 - 0.0018 19.0 19.5 6.1 7.9 0.0 8.2 5 3 4 9 9 9 2 Tetratricopeptide repeat DUF410 PF04190.13 KXS95705.1 - 0.051 13.4 0.4 0.16 11.8 0.0 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF410) TPR_16 PF13432.6 KXS95705.1 - 0.19 12.4 14.2 5.9 7.6 5.2 5.3 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXS95705.1 - 0.36 11.1 12.4 38 4.7 0.0 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 KXS95705.1 - 0.56 10.4 0.0 0.56 10.4 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXS95705.1 - 5.7 7.8 10.3 30 5.5 0.2 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat AAA PF00004.29 KXS95708.1 - 5.6e-16 59.2 0.0 9.2e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KXS95708.1 - 0.00027 20.7 0.0 0.00049 19.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KXS95708.1 - 0.001 19.3 0.5 0.027 14.8 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 KXS95708.1 - 0.0024 18.1 0.0 0.0092 16.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXS95708.1 - 0.012 16.1 0.3 0.035 14.5 0.1 2.0 2 1 0 2 2 2 0 AAA ATPase domain ATPase PF06745.13 KXS95708.1 - 0.13 11.6 0.1 0.58 9.5 0.1 2.0 2 0 0 2 2 2 0 KaiC TIP49 PF06068.13 KXS95708.1 - 0.14 11.3 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain MFS_1 PF07690.16 KXS95709.1 - 5.8e-29 101.1 35.1 2.1e-28 99.3 36.3 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KXS95709.1 - 5.3e-05 22.7 4.8 5.3e-05 22.7 4.8 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Glyco_hydro_18 PF00704.28 KXS95712.1 - 1e-13 51.8 0.2 1.2e-13 51.5 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 FRQ PF09421.10 KXS95712.1 - 0.0066 14.5 0.0 0.009 14.1 0.0 1.1 1 0 0 1 1 1 1 Frequency clock protein BtpA PF03437.15 KXS95712.1 - 0.13 11.6 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 BtpA family Acyltransferase PF01553.21 KXS95713.1 - 1.2e-14 54.1 0.0 2.5e-14 53.0 0.0 1.5 1 1 0 1 1 1 1 Acyltransferase Acyltransferase PF01553.21 KXS95714.1 - 2.8e-05 23.8 0.0 5.1e-05 22.9 0.0 1.4 1 1 0 1 1 1 1 Acyltransferase Acyltransferase PF01553.21 KXS95716.1 - 1.5e-14 53.8 0.0 3.1e-14 52.8 0.0 1.5 1 1 0 1 1 1 1 Acyltransferase Zn_clus PF00172.18 KXS95717.1 - 1.4e-08 34.7 10.2 2.5e-08 33.9 10.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXS95717.1 - 1.5e-06 27.3 0.2 2e-06 26.9 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain HET PF06985.11 KXS95718.1 - 5.5e-32 111.1 0.0 1.1e-31 110.2 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ras PF00071.22 KXS95719.1 - 4.4e-55 185.7 0.0 5.5e-55 185.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXS95719.1 - 1.1e-31 109.5 0.0 1.6e-31 109.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXS95719.1 - 5.8e-12 45.4 0.0 6.9e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KXS95719.1 - 1.2e-07 31.8 0.0 1.8e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KXS95719.1 - 7e-06 25.6 0.0 8.5e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KXS95719.1 - 7.3e-06 25.7 0.0 0.00026 20.6 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KXS95719.1 - 0.00046 20.1 0.1 0.0046 16.9 0.1 2.2 1 1 2 3 3 3 1 RsgA GTPase AAA_5 PF07728.14 KXS95719.1 - 0.0057 16.6 0.0 0.014 15.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.17 KXS95719.1 - 0.0065 16.3 0.3 0.18 11.6 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 KXS95719.1 - 0.0093 16.4 0.0 0.017 15.5 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXS95719.1 - 0.0099 16.1 0.0 0.017 15.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 KXS95719.1 - 0.011 15.1 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 KXS95719.1 - 0.012 15.4 0.1 0.12 12.1 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 KXS95719.1 - 0.017 14.7 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 KXS95719.1 - 0.022 14.5 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 KXS95719.1 - 0.022 14.0 0.0 0.047 13.0 0.0 1.6 1 0 0 1 1 1 0 Septin AAA_7 PF12775.7 KXS95719.1 - 0.026 14.0 0.1 0.046 13.2 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 KXS95719.1 - 0.074 12.9 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KXS95719.1 - 0.084 12.0 0.0 0.3 10.2 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain Glyco_hydro_75 PF07335.11 KXS95719.1 - 0.11 12.8 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Fungal chitosanase of glycosyl hydrolase group 75 NACHT PF05729.12 KXS95719.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain TniB PF05621.11 KXS95719.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein NTPase_1 PF03266.15 KXS95719.1 - 0.16 11.9 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 NTPase WSC PF01822.19 KXS95720.1 - 5.2e-09 36.2 12.3 1.5e-08 34.7 12.3 1.8 1 0 0 1 1 1 1 WSC domain PTP_tm PF18861.1 KXS95720.1 - 0.00041 20.4 0.1 0.0015 18.6 0.0 1.9 2 0 0 2 2 2 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J Podoplanin PF05808.11 KXS95720.1 - 0.0026 17.9 9.5 0.0062 16.6 9.5 1.6 1 0 0 1 1 1 1 Podoplanin PepSY_TM PF03929.16 KXS95720.1 - 0.0081 15.9 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 PepSY-associated TM region DUF4536 PF15055.6 KXS95720.1 - 0.039 14.2 0.0 0.13 12.6 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4536) SCF PF02404.15 KXS95720.1 - 0.13 11.6 1.1 0.44 9.8 0.0 1.9 1 1 1 2 2 2 0 Stem cell factor MtrF PF09472.10 KXS95720.1 - 1.9 7.9 4.3 21 4.6 5.2 2.1 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) SKG6 PF08693.10 KXS95720.1 - 1.9 8.0 8.2 0.1 12.0 1.7 2.2 2 0 0 2 2 2 0 Transmembrane alpha-helix domain TMEM154 PF15102.6 KXS95720.1 - 3 7.7 9.9 1.1e+02 2.7 9.9 2.5 1 1 0 1 1 1 0 TMEM154 protein family WSC PF01822.19 KXS95721.1 - 1.3e-08 34.9 12.3 1.3e-08 34.9 12.3 1.9 2 0 0 2 2 2 1 WSC domain Podoplanin PF05808.11 KXS95721.1 - 0.00035 20.7 1.8 0.00078 19.6 1.8 1.5 1 0 0 1 1 1 1 Podoplanin PTP_tm PF18861.1 KXS95721.1 - 0.00066 19.7 1.1 0.0013 18.8 0.0 2.0 3 0 0 3 3 3 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J PepSY_TM PF03929.16 KXS95721.1 - 0.012 15.3 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 PepSY-associated TM region TMEM154 PF15102.6 KXS95721.1 - 0.027 14.4 1.4 18 5.2 0.0 2.3 1 1 1 2 2 2 0 TMEM154 protein family DUF4536 PF15055.6 KXS95721.1 - 0.034 14.4 0.0 0.11 12.7 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4536) GRA6 PF05084.13 KXS95721.1 - 0.046 13.7 0.3 0.046 13.7 0.3 2.3 1 1 0 2 2 2 0 Granule antigen protein (GRA6) SCF PF02404.15 KXS95721.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Stem cell factor DUF3318 PF11780.8 KXS95721.1 - 0.21 11.5 0.2 0.43 10.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) Alpha_GJ PF03229.13 KXS95721.1 - 1.4 9.5 20.1 17 6.0 1.6 3.3 2 1 1 3 3 3 0 Alphavirus glycoprotein J MtrF PF09472.10 KXS95721.1 - 1.6 8.2 4.3 18 4.8 5.2 2.1 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) SKG6 PF08693.10 KXS95721.1 - 1.7 8.1 8.2 0.092 12.2 1.7 2.2 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Exo_endo_phos PF03372.23 KXS95722.1 - 3.9e-05 23.3 0.0 7.6e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-RING_UBOX PF13445.6 KXS95723.1 - 8.7e-07 28.9 13.1 0.00038 20.4 1.5 3.3 2 2 1 3 3 3 2 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KXS95723.1 - 1.1e-06 28.4 18.9 0.0013 18.5 9.0 2.9 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-NOSIP PF15906.5 KXS95723.1 - 1.6e-06 28.1 0.0 3.9e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_2 PF13639.6 KXS95723.1 - 1.2e-05 25.5 18.9 0.0033 17.7 6.9 3.5 3 1 1 4 4 4 2 Ring finger domain FYVE PF01363.21 KXS95723.1 - 4e-05 23.7 13.4 4.3e-05 23.6 6.3 2.5 2 0 0 2 2 2 1 FYVE zinc finger zf-C3HC4 PF00097.25 KXS95723.1 - 4.3e-05 23.3 15.9 0.005 16.7 6.3 2.9 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXS95723.1 - 0.00011 22.0 19.9 0.0091 15.8 2.2 3.7 4 1 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXS95723.1 - 0.00037 20.4 8.1 0.00037 20.4 8.1 2.8 2 1 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KXS95723.1 - 0.0019 18.0 22.3 0.29 11.0 10.3 3.9 2 1 1 3 3 3 2 Prokaryotic RING finger family 4 Rtf2 PF04641.12 KXS95723.1 - 0.0035 16.7 13.4 0.0038 16.6 3.3 2.9 2 1 1 3 3 3 2 Rtf2 RING-finger zf-C3HC4_4 PF15227.6 KXS95723.1 - 0.02 15.1 19.4 0.24 11.6 3.1 3.9 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING IBR PF01485.21 KXS95723.1 - 0.067 13.4 15.7 1.9 8.8 0.6 3.3 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain TerB_C PF15615.6 KXS95723.1 - 0.27 11.5 6.0 0.046 14.0 1.4 2.0 2 0 0 2 2 2 0 TerB-C domain Prok-RING_1 PF14446.6 KXS95723.1 - 0.67 9.9 14.2 0.51 10.3 3.9 3.3 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 RTA1 PF04479.13 KXS95726.1 - 1e-69 234.3 8.0 1.4e-69 233.9 8.0 1.2 1 0 0 1 1 1 1 RTA1 like protein DHHC PF01529.20 KXS95726.1 - 0.021 14.9 3.7 4 7.5 1.3 2.5 2 0 0 2 2 2 0 DHHC palmitoyltransferase DUF3328 PF11807.8 KXS95727.1 - 2.6e-21 76.4 2.1 3.6e-21 76.0 1.4 1.5 1 1 1 2 2 2 1 Domain of unknown function (DUF3328) ArfGap PF01412.18 KXS95728.1 - 2e-30 105.3 0.1 3.5e-30 104.5 0.1 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Solute_trans_a PF03619.16 KXS95729.1 - 4.8e-92 308.2 20.6 5.7e-92 308.0 20.6 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha PrgI PF12666.7 KXS95729.1 - 0.038 14.7 0.9 0.038 14.7 0.9 2.6 2 1 0 2 2 2 0 PrgI family protein TssN PF17555.2 KXS95729.1 - 3 7.2 14.7 0.1 11.9 2.2 2.2 2 0 0 2 2 2 0 Type VI secretion system, TssN BaxI_1 PF12811.7 KXS95729.1 - 4.3 6.8 11.8 0.13 11.8 0.8 2.4 2 0 0 2 2 2 0 Bax inhibitor 1 like DPM3 PF08285.11 KXS95729.1 - 6.8 7.0 12.1 0.11 12.7 1.9 2.8 2 2 1 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) GATase PF00117.28 KXS95731.1 - 7.3e-47 159.6 0.0 1.3e-46 158.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 KXS95731.1 - 1.3e-44 151.1 0.0 8.6e-44 148.5 0.0 2.1 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.13 KXS95731.1 - 6.7e-06 26.0 0.1 0.00029 20.7 0.1 2.5 1 1 0 1 1 1 1 Peptidase C26 SNARE PF05739.19 KXS95734.1 - 1.5e-11 44.1 0.1 1.5e-11 44.1 0.1 1.8 2 0 0 2 2 1 1 SNARE domain Syntaxin-5_N PF11416.8 KXS95734.1 - 3.5e-10 38.8 0.6 8.3e-10 37.6 0.6 1.7 1 0 0 1 1 1 1 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin PF00804.25 KXS95734.1 - 0.00011 22.0 10.0 0.0043 16.8 0.2 2.7 2 1 1 3 3 3 2 Syntaxin Syntaxin-18_N PF10496.9 KXS95734.1 - 0.0019 18.4 1.0 0.12 12.6 0.1 2.7 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus DUF148 PF02520.17 KXS95734.1 - 0.025 14.7 10.2 0.35 11.0 3.7 2.7 2 1 0 2 2 2 0 Domain of unknown function DUF148 Snapin_Pallidin PF14712.6 KXS95734.1 - 0.039 14.4 11.8 0.97 9.9 0.0 3.7 4 0 0 4 4 3 0 Snapin/Pallidin GIT_CC PF16559.5 KXS95734.1 - 0.039 13.8 1.0 0.21 11.5 0.1 2.5 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF16 PF01519.16 KXS95734.1 - 0.052 14.0 8.5 0.12 12.8 0.7 2.6 2 1 0 2 2 2 0 Protein of unknown function DUF16 LXG PF04740.12 KXS95734.1 - 0.052 13.2 0.4 0.052 13.2 0.4 2.6 2 1 0 2 2 2 0 LXG domain of WXG superfamily DUF948 PF06103.11 KXS95734.1 - 0.11 12.7 2.6 1.6 9.1 0.0 3.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) zf-C4H2 PF10146.9 KXS95734.1 - 0.25 11.6 6.4 1.8 8.8 1.6 2.4 1 1 1 2 2 2 0 Zinc finger-containing protein BLOC1_2 PF10046.9 KXS95734.1 - 0.39 11.1 3.4 3.3 8.1 0.2 2.8 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.11 KXS95734.1 - 0.88 8.4 6.6 2.3 7.0 0.3 2.4 2 0 0 2 2 2 0 Spc7 kinetochore protein Mer2 PF09074.10 KXS95734.1 - 1 9.2 6.7 0.96 9.2 2.0 2.1 2 0 0 2 2 2 0 Mer2 LPP PF04728.13 KXS95734.1 - 1.2 9.6 7.5 2.6 8.5 1.3 2.6 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Fib_alpha PF08702.10 KXS95734.1 - 2.8 8.1 8.5 15 5.7 0.1 2.8 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family SlyX PF04102.12 KXS95734.1 - 3.2 8.4 13.0 1.2 9.8 1.2 3.5 3 0 0 3 3 3 0 SlyX DUF1664 PF07889.12 KXS95734.1 - 4.8 7.2 8.5 3.1 7.8 0.4 3.1 3 1 1 4 4 3 0 Protein of unknown function (DUF1664) DivIC PF04977.15 KXS95734.1 - 7.4 6.4 8.0 1.3 8.8 0.4 3.0 3 0 0 3 3 3 0 Septum formation initiator Prominin PF05478.11 KXS95734.1 - 8 4.3 7.7 11 3.8 2.4 2.4 2 1 0 2 2 2 0 Prominin ABC_tran_CTD PF16326.5 KXS95734.1 - 9.4 6.6 7.3 8.5 6.7 0.4 3.1 2 2 2 4 4 4 0 ABC transporter C-terminal domain MFS_1 PF07690.16 KXS95735.1 - 1e-42 146.4 29.6 1e-42 146.4 29.6 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS95735.1 - 4e-15 55.6 4.1 4e-15 55.6 4.1 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KXS95735.1 - 0.00016 20.3 0.9 0.00024 19.7 0.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Mntp PF02659.15 KXS95735.1 - 0.23 11.2 0.1 0.23 11.2 0.1 2.7 4 1 0 4 4 4 0 Putative manganese efflux pump MFS_1 PF07690.16 KXS95736.1 - 9e-33 113.6 31.4 2.4e-32 112.2 29.5 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS95736.1 - 6.8e-12 45.0 9.6 6.8e-12 45.0 9.6 2.6 2 1 1 3 3 3 1 Sugar (and other) transporter MAP17 PF15807.5 KXS95736.1 - 1.7 8.9 3.3 7.6 6.8 0.0 2.8 3 0 0 3 3 3 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 ADH_zinc_N PF00107.26 KXS95737.1 - 1.5e-21 76.7 0.1 2.8e-21 75.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXS95737.1 - 3.3e-20 72.0 0.3 7.4e-20 70.9 0.1 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 KXS95737.1 - 5.5e-05 22.8 0.2 0.00012 21.6 0.2 1.5 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KXS95737.1 - 0.032 15.3 0.0 0.07 14.2 0.0 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 KXS95737.1 - 1.2 8.6 5.3 0.21 11.2 0.7 2.0 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Peptidase_S10 PF00450.22 KXS95738.1 - 2e-98 330.6 0.5 2.9e-98 330.0 0.5 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase PAPS_reduct PF01507.19 KXS95743.1 - 5.6e-43 147.0 0.0 7.4e-43 146.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family LamB PF02264.15 KXS95744.1 - 0.03 14.3 0.5 1.8 8.4 0.0 2.1 2 0 0 2 2 2 0 LamB porin Peptidase_A25 PF03418.14 KXS95746.1 - 0.12 11.2 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Germination protease BPL_LplA_LipB PF03099.19 KXS95753.1 - 5.7e-09 36.0 0.0 9.8e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family ECH_1 PF00378.20 KXS95758.1 - 2.8e-37 128.4 0.0 4.7e-36 124.4 0.0 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXS95758.1 - 1e-30 107.4 0.0 1.8e-28 100.0 0.0 2.7 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase DUF4875 PF16175.5 KXS95758.1 - 0.045 13.9 0.0 0.14 12.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4875) ECH_1 PF00378.20 KXS95760.1 - 2.8e-37 128.4 0.0 4.7e-36 124.4 0.0 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXS95760.1 - 1e-30 107.4 0.0 1.8e-28 100.0 0.0 2.7 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase DUF4875 PF16175.5 KXS95760.1 - 0.045 13.9 0.0 0.14 12.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4875) ECH_1 PF00378.20 KXS95761.1 - 2.8e-37 128.4 0.0 4.7e-36 124.4 0.0 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXS95761.1 - 1e-30 107.4 0.0 1.8e-28 100.0 0.0 2.7 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase DUF4875 PF16175.5 KXS95761.1 - 0.045 13.9 0.0 0.14 12.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4875) Forkhead PF00250.18 KXS95762.1 - 3.3e-20 72.1 0.0 6.3e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 Forkhead domain Endonuc-EcoRV PF09233.11 KXS95764.1 - 0.0057 16.0 0.0 0.068 12.5 0.0 2.1 2 0 0 2 2 2 1 Restriction endonuclease EcoRV ANT PF03374.14 KXS95764.1 - 0.067 13.5 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 Phage antirepressor protein KilAC domain ApbA PF02558.16 KXS95765.1 - 1.8e-31 108.9 0.0 4e-31 107.7 0.0 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KXS95765.1 - 1.4e-25 89.9 0.0 2.2e-25 89.3 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal NAD_binding_7 PF13241.6 KXS95765.1 - 0.073 13.5 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Pkinase PF00069.25 KXS95766.1 - 2e-16 60.2 0.0 3.8e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS95766.1 - 2e-07 30.6 0.0 3.6e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXS95766.1 - 0.0068 16.3 2.9 0.0069 16.3 0.1 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family An_peroxidase PF03098.15 KXS95767.1 - 6.8e-122 407.7 0.0 8.5e-122 407.4 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase AAL_decarboxy PF03306.13 KXS95769.1 - 8.1e-37 126.7 0.0 6.1e-23 81.3 0.0 2.0 1 1 1 2 2 2 2 Alpha-acetolactate decarboxylase EMP70 PF02990.16 KXS95770.1 - 4.3e-199 662.5 0.5 5.4e-199 662.2 0.5 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 CrgA PF06781.12 KXS95770.1 - 1.7 8.7 7.9 10 6.3 0.1 3.6 3 0 0 3 3 3 0 Cell division protein CrgA DUF3328 PF11807.8 KXS95771.1 - 2e-28 99.7 1.6 2.6e-28 99.3 1.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) FMO-like PF00743.19 KXS95774.1 - 4.7e-16 58.3 0.0 2.4e-14 52.7 0.0 2.5 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KXS95774.1 - 9.1e-07 29.0 0.0 2.1e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXS95774.1 - 0.075 12.2 0.0 4.1 6.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXS95774.1 - 0.16 11.1 0.1 11 5.0 0.0 2.9 3 1 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) ZapB PF06005.12 KXS95775.1 - 0.021 15.2 0.1 0.08 13.4 0.1 1.9 1 0 0 1 1 1 0 Cell division protein ZapB DUF5352 PF17303.2 KXS95775.1 - 0.22 11.4 0.0 1.7 8.5 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5352) DivIC PF04977.15 KXS95775.1 - 1.5 8.6 3.0 1.2 9.0 0.5 2.1 2 0 0 2 2 2 0 Septum formation initiator Metallophos PF00149.28 KXS95776.1 - 8.2e-06 26.4 2.2 6.6e-05 23.5 2.2 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase XLF PF09302.11 KXS95777.1 - 4.1e-38 131.3 0.0 1.1e-37 129.9 0.0 1.8 1 0 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component Brix PF04427.18 KXS95780.1 - 5.4e-47 160.4 0.2 8.2e-47 159.8 0.2 1.2 1 0 0 1 1 1 1 Brix domain HD_4 PF13328.6 KXS95780.1 - 0.14 11.9 0.1 0.14 11.9 0.1 2.3 2 0 0 2 2 2 0 HD domain PA26 PF04636.13 KXS95780.1 - 1.4 7.7 5.9 2.5 6.9 5.9 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Homeodomain PF00046.29 KXS95781.1 - 6.2e-18 64.4 4.2 1.1e-17 63.5 4.2 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KXS95781.1 - 0.001 18.9 0.2 0.001 18.9 0.2 2.0 2 0 0 2 2 2 1 Homeobox KN domain Lactamase_B_5 PF14597.6 KXS95782.1 - 0.0058 16.1 0.0 0.0075 15.8 0.0 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily MIF4G PF02854.19 KXS95783.1 - 4e-47 160.6 1.1 7.5e-47 159.7 0.0 1.9 2 0 0 2 2 2 1 MIF4G domain eIF_4G1 PF12152.8 KXS95783.1 - 2e-21 75.9 0.8 6e-21 74.4 0.8 1.9 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 ECH_1 PF00378.20 KXS95784.1 - 2.3e-74 249.9 0.0 2.7e-74 249.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXS95784.1 - 3.1e-36 125.5 0.1 3.8e-32 112.1 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Phage_holin_7_1 PF16081.5 KXS95785.1 - 0.27 11.4 5.6 0.3 11.3 5.6 1.1 1 0 0 1 1 1 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family DUF515 PF04415.12 KXS95785.1 - 1.9 6.8 4.0 2.3 6.5 4.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF515) efThoc1 PF11957.8 KXS95786.1 - 1e-119 400.4 0.1 1.2e-119 400.2 0.1 1.0 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor 4HBT PF03061.22 KXS95787.1 - 3.7e-15 56.0 0.1 1.7e-14 53.9 0.1 1.9 1 1 1 2 2 2 1 Thioesterase superfamily DUF4442 PF14539.6 KXS95787.1 - 0.029 14.5 0.0 0.056 13.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) 4HBT_3 PF13622.6 KXS95787.1 - 0.057 13.7 0.0 0.071 13.4 0.0 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily DUF3419 PF11899.8 KXS95788.1 - 1e-157 525.3 0.0 1.4e-157 524.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.6 KXS95788.1 - 1.7e-08 34.5 0.0 9.6e-08 32.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS95788.1 - 2.4e-08 34.6 0.1 1e-06 29.4 0.0 3.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS95788.1 - 5.8e-07 30.1 0.0 5.2e-05 23.9 0.0 3.7 4 1 1 5 5 5 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS95788.1 - 7.2e-06 26.6 0.0 0.0064 17.1 0.0 4.5 4 1 0 4 4 4 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS95788.1 - 0.00018 21.3 0.0 0.00079 19.2 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXS95788.1 - 0.00055 19.3 0.0 0.071 12.4 0.0 2.6 3 0 0 3 3 3 1 ubiE/COQ5 methyltransferase family PGM_PMM_IV PF00408.20 KXS95788.1 - 0.01 16.0 0.0 0.022 14.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PCMT PF01135.19 KXS95788.1 - 0.022 14.5 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 KXS95788.1 - 0.066 12.7 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase Swi3 PF07962.12 KXS95789.1 - 4.2e-31 106.8 0.3 6.8e-31 106.1 0.3 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 DEAD PF00270.29 KXS95790.1 - 2.1e-47 161.2 0.0 3.6e-47 160.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXS95790.1 - 1.4e-30 105.9 0.1 2.9e-29 101.7 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXS95790.1 - 3.7e-07 30.3 0.0 1.3e-06 28.5 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 KXS95790.1 - 0.035 12.8 0.0 0.049 12.4 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain Rer1 PF03248.13 KXS95792.1 - 2.2e-76 255.3 4.6 2.6e-76 255.2 4.6 1.0 1 0 0 1 1 1 1 Rer1 family Oxidored_q4 PF00507.19 KXS95792.1 - 2.1 8.5 9.4 0.087 13.0 1.8 2.0 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 HSF_DNA-bind PF00447.17 KXS95793.1 - 1.8e-17 63.7 0.1 3.8e-17 62.7 0.1 1.6 1 1 0 1 1 1 1 HSF-type DNA-binding DUF2408 PF10303.9 KXS95793.1 - 0.14 12.7 0.0 0.24 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) HSF_DNA-bind PF00447.17 KXS95794.1 - 2.2e-30 105.1 0.9 3.9e-30 104.3 0.9 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding DUF2408 PF10303.9 KXS95794.1 - 0.12 12.9 0.0 0.23 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) BatD PF13584.6 KXS95797.1 - 0.00089 18.2 0.0 0.0012 17.8 0.0 1.1 1 0 0 1 1 1 1 Oxygen tolerance DUF4064 PF13273.6 KXS95797.1 - 0.046 14.0 0.1 0.082 13.2 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) MAP17 PF15807.5 KXS95797.1 - 0.08 13.2 0.0 1.7 8.9 0.0 2.2 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 SARAF PF06682.12 KXS95797.1 - 0.09 12.4 0.2 0.19 11.3 0.2 1.7 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF3301 PF11743.8 KXS95797.1 - 0.15 11.7 0.1 0.31 10.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) TMEM154 PF15102.6 KXS95797.1 - 0.16 11.8 0.3 0.34 10.8 0.3 1.5 1 1 0 1 1 1 0 TMEM154 protein family SKG6 PF08693.10 KXS95797.1 - 0.27 10.7 4.0 0.79 9.2 4.0 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain OAD_gamma PF04277.13 KXS95797.1 - 0.42 11.2 2.8 24 5.6 0.1 3.1 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain TrbC PF04956.13 KXS95797.1 - 2.9 8.1 4.8 8 6.8 0.6 2.2 2 0 0 2 2 2 0 TrbC/VIRB2 family GFA PF04828.14 KXS95798.1 - 1.1e-24 86.5 0.6 1.4e-24 86.2 0.0 1.4 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Zn_ribbon_recom PF13408.6 KXS95798.1 - 0.079 13.5 0.1 0.079 13.5 0.1 2.5 2 1 1 3 3 3 0 Recombinase zinc beta ribbon domain G_glu_transpept PF01019.21 KXS95799.1 - 4.7e-137 457.9 0.0 5.4e-137 457.7 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Mal_decarbox_Al PF16957.5 KXS95799.1 - 0.082 11.2 0.0 0.12 10.6 0.0 1.2 1 0 0 1 1 1 0 Malonate decarboxylase, alpha subunit, transporter TPR_12 PF13424.6 KXS95800.1 - 3.1e-07 30.6 6.7 0.014 15.6 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 KXS95800.1 - 0.00013 21.7 2.2 2.3 8.4 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXS95800.1 - 0.00014 21.7 14.7 1.3 9.3 0.3 5.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXS95800.1 - 0.0021 17.8 10.0 0.17 11.7 0.6 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXS95800.1 - 0.0023 18.6 2.8 3.5 8.7 0.1 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXS95800.1 - 0.0053 16.9 8.7 4.9 7.6 0.4 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 KXS95800.1 - 0.6 10.1 7.4 4.4 7.3 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Acetyltransf_7 PF13508.7 KXS95801.1 - 2.7e-10 40.5 0.0 3.8e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXS95801.1 - 2.6e-09 37.3 0.0 3.5e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXS95801.1 - 0.00051 20.0 0.0 0.0015 18.5 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXS95801.1 - 0.0067 16.5 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 KXS95801.1 - 0.011 15.8 0.0 0.11 12.5 0.0 2.2 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain 2OG-FeII_Oxy_2 PF13532.6 KXS95802.1 - 6.1e-28 98.4 0.2 1.1e-27 97.5 0.2 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.20 KXS95802.1 - 2.1e-26 93.2 0.0 3.7e-25 89.1 0.0 2.8 2 1 0 2 2 2 1 Isochorismatase family ADH_N PF08240.12 KXS95803.1 - 2.1e-27 95.2 1.8 3.6e-27 94.4 1.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXS95803.1 - 1.4e-13 51.0 0.0 2.2e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXS95803.1 - 3.4e-07 30.0 0.2 8.1e-06 25.5 0.2 2.5 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KXS95803.1 - 0.073 14.1 0.0 0.14 13.2 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KXS95803.1 - 0.08 12.2 0.2 0.29 10.4 0.0 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Prot_ATP_ID_OB PF16450.5 KXS95803.1 - 0.17 11.9 0.0 0.34 10.9 0.0 1.4 1 0 0 1 1 1 0 Proteasomal ATPase OB C-terminal domain Sas10_Utp3 PF04000.15 KXS95804.1 - 2.9e-08 34.2 0.1 2.9e-08 34.2 0.1 1.9 2 0 0 2 2 2 1 Sas10/Utp3/C1D family CDC45 PF02724.14 KXS95804.1 - 0.7 8.1 13.2 0.91 7.7 12.9 1.3 1 1 0 1 1 1 0 CDC45-like protein CDV3 PF15359.6 KXS95804.1 - 1.4 9.4 8.3 0.55 10.7 4.5 2.1 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 Antifungal_prot PF11402.8 KXS95805.1 - 1.2 9.4 4.6 2.9 8.2 4.6 1.6 1 0 0 1 1 1 0 Antifungal protein p450 PF00067.22 KXS95808.1 - 6.8e-62 209.7 0.0 2.8e-60 204.4 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 Glyco_hydro_43 PF04616.14 KXS95809.1 - 1e-15 57.8 8.6 1.3e-15 57.4 7.2 1.8 1 1 1 2 2 2 1 Glycosyl hydrolases family 43 CBM60 PF16841.5 KXS95809.1 - 0.084 13.3 0.2 1.7 9.1 0.0 2.9 1 1 2 3 3 3 0 Ca-dependent carbohydrate-binding module xylan-binding SRAP PF02586.14 KXS95810.1 - 7.8e-84 280.6 0.0 1.2e-83 280.0 0.0 1.3 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) Amidase_6 PF12671.7 KXS95810.1 - 0.066 13.3 0.1 0.066 13.3 0.1 1.7 2 0 0 2 2 2 0 Putative amidase domain Glyco_hydro_47 PF01532.20 KXS95812.1 - 3.1e-121 405.5 0.0 3.7e-121 405.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_76 PF03663.14 KXS95812.1 - 0.014 14.9 1.0 0.072 12.6 0.2 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 76 Acyl-CoA_dh_1 PF00441.24 KXS95813.1 - 3.5e-28 98.7 1.1 5.6e-28 98.0 1.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KXS95813.1 - 4.9e-18 65.8 0.0 1.2e-17 64.6 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KXS95813.1 - 1.8e-17 63.3 0.0 3.2e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KXS95813.1 - 6.6e-12 45.8 1.8 1.2e-11 45.0 1.8 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Tfb5 PF06331.12 KXS95814.1 - 5.6e-24 83.9 0.3 6.2e-24 83.8 0.3 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 OmpH PF03938.14 KXS95814.1 - 0.038 14.3 0.2 0.044 14.1 0.2 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) YrhK PF14145.6 KXS95816.1 - 0.00011 22.0 22.9 0.011 15.6 2.9 4.9 3 2 1 4 4 4 3 YrhK-like protein OATP PF03137.20 KXS95816.1 - 0.23 9.7 9.3 0.29 9.4 8.5 1.5 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF983 PF06170.12 KXS95816.1 - 0.3 11.5 3.5 2.4 8.6 0.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF983) DUF973 PF06157.11 KXS95816.1 - 1.1 8.3 7.3 5.3 6.0 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF973) Iso_dh PF00180.20 KXS95817.1 - 1.2e-93 314.1 0.0 1.1e-74 251.7 0.0 2.0 1 1 1 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase MFS_1 PF07690.16 KXS95818.1 - 6.7e-31 107.5 35.1 8.2e-30 103.9 27.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PetM PF08041.11 KXS95818.1 - 0.0069 15.9 0.1 0.03 13.9 0.1 2.2 1 0 0 1 1 1 1 PetM family of cytochrome b6f complex subunit 7 Ribosomal_S19e PF01090.19 KXS95821.1 - 8.6e-59 197.2 0.2 9.8e-59 197.0 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e ParA PF10609.9 KXS95826.1 - 0.013 14.9 0.0 0.015 14.8 0.0 1.0 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase DUF2063 PF09836.9 KXS95827.1 - 0.022 15.0 0.0 2 8.7 0.0 2.8 2 1 1 3 3 3 0 Putative DNA-binding domain zf-C2H2_jaz PF12171.8 KXS95829.1 - 0.0003 21.0 0.4 0.00066 19.9 0.4 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KXS95829.1 - 0.003 18.3 6.3 0.23 12.4 0.5 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KXS95829.1 - 0.004 17.5 6.6 0.57 10.8 0.6 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type Ima1_N PF09779.9 KXS95829.1 - 0.075 13.9 0.2 0.075 13.9 0.2 2.3 2 0 0 2 2 2 0 Ima1 N-terminal domain Pox_G9-A16 PF03003.16 KXS95829.1 - 1.4 8.7 3.9 0.35 10.6 0.6 1.6 2 0 0 2 2 2 0 Pox virus entry-fusion-complex G9/A16 Spherulin4 PF12138.8 KXS95831.1 - 1.1e-89 300.2 2.8 6e-62 209.4 0.4 2.1 2 0 0 2 2 2 2 Spherulation-specific family 4 Abhydrolase_1 PF00561.20 KXS95832.1 - 4.7e-21 75.6 0.0 1.4e-20 74.0 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXS95832.1 - 1.3e-16 61.9 0.0 2.3e-16 61.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DSPc PF00782.20 KXS95832.1 - 2.8e-13 49.8 0.0 7e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Hydrolase_4 PF12146.8 KXS95832.1 - 5.5e-11 42.2 0.0 1.4e-10 40.9 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 KXS95832.1 - 0.00017 21.4 0.1 0.0018 18.0 0.1 2.1 1 1 0 1 1 1 1 PGAP1-like protein PTPlike_phytase PF14566.6 KXS95832.1 - 0.0074 16.4 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate Thioesterase PF00975.20 KXS95832.1 - 0.0084 16.2 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain LCAT PF02450.15 KXS95832.1 - 0.016 14.4 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase LIDHydrolase PF10230.9 KXS95832.1 - 0.034 13.7 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Abhydrolase_2 PF02230.16 KXS95832.1 - 0.045 13.6 0.0 6.6 6.5 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Y_phosphatase PF00102.27 KXS95832.1 - 0.049 13.2 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Chlorophyllase2 PF12740.7 KXS95832.1 - 0.051 12.5 0.0 0.14 11.1 0.0 1.7 1 1 0 1 1 1 0 Chlorophyllase enzyme Y_phosphatase3 PF13350.6 KXS95832.1 - 0.1 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Lipase_3 PF01764.25 KXS95832.1 - 0.12 12.2 0.2 0.57 10.1 0.0 1.9 1 1 0 2 2 2 0 Lipase (class 3) Ser_hydrolase PF06821.13 KXS95832.1 - 0.13 12.1 0.1 1.7 8.5 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase Epimerase PF01370.21 KXS95833.1 - 4.2e-05 23.1 0.0 4.5e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXS95833.1 - 0.0014 18.1 0.0 0.0014 18.1 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase FHIPEP PF00771.20 KXS95835.1 - 0.01 14.3 0.5 0.016 13.7 0.5 1.2 1 0 0 1 1 1 0 FHIPEP family Ribosomal_60s PF00428.19 KXS95835.1 - 0.045 14.4 10.2 0.045 14.4 10.2 3.1 3 0 0 3 3 3 0 60s Acidic ribosomal protein Med3 PF11593.8 KXS95835.1 - 0.58 9.3 4.3 0.81 8.8 4.3 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF4710 PF15828.5 KXS95835.1 - 2.9 8.1 14.4 19 5.4 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) AAA PF00004.29 KXS95836.1 - 8.6e-18 65.0 0.0 1.7e-17 64.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXS95836.1 - 0.00023 21.6 0.3 0.00075 19.9 0.1 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KXS95836.1 - 0.00027 21.0 0.0 0.00072 19.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KXS95836.1 - 0.00086 19.9 0.0 0.0042 17.6 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KXS95836.1 - 0.00087 19.6 2.4 0.025 14.8 0.0 3.0 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.12 KXS95836.1 - 0.0077 16.0 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KXS95836.1 - 0.057 13.5 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) ATPase PF06745.13 KXS95836.1 - 0.069 12.5 1.2 0.13 11.6 0.2 1.9 2 0 0 2 2 2 0 KaiC AAA_17 PF13207.6 KXS95836.1 - 0.083 13.3 0.0 0.25 11.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KXS95836.1 - 0.16 12.1 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain SGL PF08450.12 KXS95840.1 - 2.3e-59 200.9 0.0 2.8e-59 200.7 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Phytase-like PF13449.6 KXS95840.1 - 0.14 12.1 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Esterase-like activity of phytase NAD_binding_11 PF14833.6 KXS95841.1 - 7.9e-34 116.5 1.9 1.9e-23 83.0 0.1 2.6 2 1 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 KXS95841.1 - 8.8e-33 113.7 1.6 9.5e-33 113.6 0.4 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 KXS95841.1 - 6.6e-05 22.3 0.4 0.001 18.4 0.1 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KXS95841.1 - 7.9e-05 22.6 0.2 0.00014 21.8 0.2 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KXS95841.1 - 0.017 15.7 0.2 0.04 14.5 0.2 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.9 KXS95841.1 - 0.047 13.6 1.5 0.23 11.3 0.3 2.7 3 0 0 3 3 3 0 Rossmann-like domain UDPG_MGDP_dh PF00984.19 KXS95841.1 - 0.08 13.2 0.0 0.88 9.8 0.0 2.6 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_binding_11 PF14833.6 KXS95842.1 - 7.9e-34 116.5 1.9 1.9e-23 83.0 0.1 2.6 2 1 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 KXS95842.1 - 8.8e-33 113.7 1.6 9.5e-33 113.6 0.4 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 KXS95842.1 - 6.6e-05 22.3 0.4 0.001 18.4 0.1 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KXS95842.1 - 7.9e-05 22.6 0.2 0.00014 21.8 0.2 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KXS95842.1 - 0.017 15.7 0.2 0.04 14.5 0.2 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.9 KXS95842.1 - 0.047 13.6 1.5 0.23 11.3 0.3 2.7 3 0 0 3 3 3 0 Rossmann-like domain UDPG_MGDP_dh PF00984.19 KXS95842.1 - 0.08 13.2 0.0 0.88 9.8 0.0 2.6 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain zf-CCCH PF00642.24 KXS95843.1 - 3.7e-09 36.3 13.2 2.5e-07 30.4 2.5 2.9 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 KXS95843.1 - 0.00024 20.9 0.0 0.00046 19.9 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 KXS95843.1 - 0.005 16.9 3.3 0.005 16.9 3.3 3.2 3 0 0 3 3 3 1 Zinc finger domain Torus PF16131.5 KXS95843.1 - 0.084 13.6 4.0 0.42 11.3 0.2 2.5 2 1 0 2 2 2 0 Torus domain zf-CCCH_3 PF15663.5 KXS95843.1 - 0.6 10.4 8.0 0.34 11.1 1.4 2.3 1 1 0 2 2 2 0 Zinc-finger containing family Helo_like_N PF17111.5 KXS95844.1 - 1e-09 38.0 0.4 3.2e-09 36.5 0.4 1.8 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Hpt PF01627.23 KXS95844.1 - 0.0019 18.4 0.5 0.055 13.7 0.0 3.1 3 0 0 3 3 3 1 Hpt domain OrfB_Zn_ribbon PF07282.11 KXS95844.1 - 0.0059 16.5 1.2 0.0059 16.5 1.2 2.1 2 0 0 2 2 2 1 Putative transposase DNA-binding domain DZR PF12773.7 KXS95844.1 - 0.075 13.1 3.5 0.12 12.4 0.6 2.4 2 0 0 2 2 2 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 KXS95844.1 - 9.5 6.4 6.5 14 5.9 2.5 3.0 2 1 2 4 4 4 0 Zinc ribbon domain RNA_pol_Rpc34 PF05158.12 KXS95847.1 - 1.2e-65 222.1 0.0 1.8e-65 221.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit MarR_2 PF12802.7 KXS95847.1 - 0.026 14.4 0.1 0.079 12.9 0.1 1.8 1 0 0 1 1 1 0 MarR family Bac_luciferase PF00296.20 KXS95848.1 - 9.4e-62 209.2 0.0 1.4e-61 208.7 0.0 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase ADH_zinc_N PF00107.26 KXS95848.1 - 6.2e-08 32.7 0.2 2.3e-07 30.8 0.1 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXS95848.1 - 0.0063 16.4 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AAA_16 PF13191.6 KXS95849.1 - 0.00043 20.7 0.1 0.0013 19.1 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KXS95849.1 - 0.00054 19.9 0.1 0.0014 18.6 0.1 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KXS95849.1 - 0.0049 17.2 0.0 1.6 9.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain Zn_clus PF00172.18 KXS95851.1 - 1.5e-10 41.0 8.7 2.2e-10 40.4 8.7 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DIOX_N PF14226.6 KXS95852.1 - 1.8e-29 102.8 0.0 3.6e-29 101.9 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXS95852.1 - 8e-14 52.0 0.0 1.5e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AMP-binding PF00501.28 KXS95853.1 - 3.4e-77 259.8 0.0 4.2e-77 259.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXS95853.1 - 1.1e-13 52.0 0.3 2.5e-13 50.8 0.3 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain adh_short_C2 PF13561.6 KXS95854.1 - 1.2e-62 211.5 0.3 2e-62 210.8 0.3 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS95854.1 - 2.3e-49 167.5 0.0 3.5e-49 166.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase TauD PF02668.16 KXS95854.1 - 1.3e-39 136.6 0.3 2.3e-39 135.8 0.1 1.4 2 0 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family KR PF08659.10 KXS95854.1 - 6.5e-11 42.5 0.3 1.2e-10 41.6 0.3 1.3 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 KXS95854.1 - 0.00011 22.1 0.0 0.00029 20.8 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 KXS95854.1 - 0.036 14.3 0.2 2 8.7 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 KXS95854.1 - 0.052 12.9 0.5 0.72 9.2 0.1 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KXS95854.1 - 0.15 11.4 1.5 2.6 7.3 0.2 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Epimerase PF01370.21 KXS95854.1 - 0.16 11.4 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KXS95854.1 - 0.16 11.8 0.1 0.33 10.8 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CbtA PF09490.10 KXS95855.1 - 0.047 13.5 0.2 0.082 12.7 0.2 1.3 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) SNARE_assoc PF09335.11 KXS95855.1 - 0.072 13.6 0.2 0.12 12.9 0.2 1.3 1 0 0 1 1 1 0 SNARE associated Golgi protein DUF515 PF04415.12 KXS95856.1 - 1.8 6.9 2.6 2.7 6.3 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Clathrin PF00637.20 KXS95857.1 - 0.017 15.0 0.2 7.9 6.3 0.2 2.5 2 0 0 2 2 2 0 Region in Clathrin and VPS PPR_2 PF13041.6 KXS95857.1 - 0.15 12.3 0.1 0.72 10.1 0.0 2.3 2 0 0 2 2 2 0 PPR repeat family Cpn60_TCP1 PF00118.24 KXS95858.1 - 2.7e-152 507.9 13.8 3e-152 507.7 13.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family EAL PF00563.20 KXS95858.1 - 0.02 14.4 0.0 0.045 13.3 0.0 1.5 1 0 0 1 1 1 0 EAL domain Glyco_hydro_17 PF00332.18 KXS95859.1 - 1.2e-18 67.8 5.2 2.5e-18 66.8 5.2 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 PAP_assoc PF03828.19 KXS95860.1 - 3.5e-17 62.3 0.1 8.1e-17 61.2 0.1 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KXS95860.1 - 4.4e-05 23.7 0.0 8.4e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nucleoside_tran PF01733.18 KXS95861.1 - 2.1e-38 132.4 3.0 7.6e-27 94.5 0.2 2.7 1 1 1 2 2 2 2 Nucleoside transporter MFS_1 PF07690.16 KXS95861.1 - 2e-08 33.6 27.4 0.00046 19.2 21.5 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Hat1_N PF10394.9 KXS95863.1 - 2.3e-41 141.7 0.0 6.7e-41 140.2 0.0 1.8 2 0 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus Mitoc_L55 PF09776.9 KXS95864.1 - 0.59 9.9 2.1 13 5.6 0.0 3.2 3 0 0 3 3 3 0 Mitochondrial ribosomal protein L55 IncE PF17627.2 KXS95865.1 - 0.096 12.7 0.9 0.31 11.0 0.9 2.0 1 0 0 1 1 1 0 Inclusion membrane protein E PalH PF08733.10 KXS95865.1 - 2 7.3 10.1 6.5 5.7 0.6 3.4 2 1 1 3 3 3 0 PalH/RIM21 ING PF12998.7 KXS95867.1 - 3.2e-08 34.1 0.1 1.2e-06 29.0 0.1 2.6 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KXS95867.1 - 4.8e-06 26.4 8.2 8.5e-06 25.6 8.2 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KXS95867.1 - 0.049 13.9 1.2 0.15 12.4 1.2 1.8 1 0 0 1 1 1 0 PHD-like zinc-binding domain Isochorismatase PF00857.20 KXS95868.1 - 6.8e-16 58.9 0.0 8.1e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Metal_resist PF13801.6 KXS95876.1 - 0.01 16.0 2.4 0.01 16.0 2.4 2.1 2 0 0 2 2 2 0 Heavy-metal resistance ROS_MUCR PF05443.11 KXS95877.1 - 0.045 13.8 0.0 0.054 13.5 0.0 1.4 1 0 0 1 1 1 0 ROS/MUCR transcriptional regulator protein MCPsignal PF00015.21 KXS95877.1 - 0.15 11.9 0.4 0.22 11.3 0.4 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain UvrD_C_2 PF13538.6 KXS95878.1 - 0.062 13.1 0.1 0.16 11.8 0.1 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DUF3326 PF11805.8 KXS95878.1 - 0.076 11.9 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3326) VasL PF12486.8 KXS95878.1 - 0.64 9.9 5.7 0.21 11.4 1.8 1.9 2 0 0 2 2 2 0 Type VI secretion system, EvfB, or VasL DUF2383 PF09537.10 KXS95879.1 - 0.069 13.5 0.2 0.3 11.5 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) SprT-like PF10263.9 KXS95889.1 - 9.8e-36 122.1 0.8 9.8e-36 122.1 0.8 2.0 3 0 0 3 3 3 1 SprT-like family Zn_ribbon_SprT PF17283.2 KXS95889.1 - 6.4e-06 26.0 3.2 1.8e-05 24.6 3.2 1.8 1 0 0 1 1 1 1 SprT-like zinc ribbon domain HMG_box PF00505.19 KXS95889.1 - 0.00052 20.4 0.0 0.0021 18.4 0.0 2.0 1 0 0 1 1 1 1 HMG (high mobility group) box Zn-ribbon_8 PF09723.10 KXS95889.1 - 0.1 12.7 1.1 0.24 11.5 1.1 1.6 1 0 0 1 1 1 0 Zinc ribbon domain Grg1 PF11034.8 KXS95890.1 - 6.3e-29 100.0 9.3 1.1e-28 99.2 9.3 1.3 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 Senescence PF06911.12 KXS95890.1 - 0.02 15.2 5.9 0.024 14.9 5.9 1.1 1 0 0 1 1 1 0 Senescence-associated protein PIN_8 PF18476.1 KXS95890.1 - 0.11 12.3 1.4 0.13 12.1 1.4 1.1 1 0 0 1 1 1 0 PIN like domain MAM33 PF02330.16 KXS95891.1 - 2.1e-46 158.6 7.2 4.1e-46 157.6 7.2 1.4 1 1 0 1 1 1 1 Mitochondrial glycoprotein zf-C3HC4_2 PF13923.6 KXS95892.1 - 4.1e-12 45.7 9.1 4.1e-12 45.7 9.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXS95892.1 - 7.2e-12 45.5 9.9 7.2e-12 45.5 9.9 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 KXS95892.1 - 8.6e-11 41.5 7.4 8.6e-11 41.5 7.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXS95892.1 - 1.1e-10 41.3 2.6 1.1e-10 41.3 2.6 2.2 2 1 1 3 3 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KXS95892.1 - 4.7e-10 39.2 9.2 4.7e-10 39.2 9.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXS95892.1 - 1.2e-08 34.7 12.4 1.7e-08 34.1 6.9 2.6 2 1 1 3 3 3 2 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KXS95892.1 - 1.4e-08 34.5 8.5 1.4e-08 34.5 8.5 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 KXS95892.1 - 1.4e-07 31.7 9.5 1.4e-07 31.7 9.5 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KXS95892.1 - 3.9e-06 26.9 13.3 6.7e-06 26.2 8.3 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Rad50_zn_hook PF04423.14 KXS95892.1 - 0.0051 16.6 3.0 0.9 9.4 0.0 3.2 3 0 0 3 3 3 1 Rad50 zinc hook motif zf-ANAPC11 PF12861.7 KXS95892.1 - 0.01 15.9 5.1 0.025 14.6 5.1 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 KXS95892.1 - 0.016 14.9 3.9 0.04 13.7 3.9 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_4 PF14570.6 KXS95892.1 - 0.037 13.8 8.6 0.037 13.8 8.6 2.5 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain Mito_fiss_reg PF05308.11 KXS95892.1 - 0.039 14.0 1.6 0.047 13.8 1.6 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator zf-RING_10 PF16685.5 KXS95892.1 - 0.058 13.5 6.2 0.12 12.5 6.2 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 DZR PF12773.7 KXS95892.1 - 0.43 10.6 10.4 0.52 10.4 1.3 2.6 2 1 1 3 3 3 0 Double zinc ribbon zf-P11 PF03854.14 KXS95892.1 - 2.5 7.8 12.8 0.05 13.3 6.1 1.7 2 0 0 2 2 1 0 P-11 zinc finger zf-C2H2_3 PF13878.6 KXS95892.1 - 3.2 7.6 0.0 3.2 7.6 0.0 3.5 3 1 1 4 4 4 0 zinc-finger of acetyl-transferase ESCO zf-RING_6 PF14835.6 KXS95892.1 - 9.3 6.2 15.1 0.064 13.1 2.7 2.5 2 1 1 3 3 2 0 zf-RING of BARD1-type protein Zn_clus PF00172.18 KXS95895.1 - 9.6e-08 32.0 11.1 1.7e-07 31.2 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_2 PF07716.15 KXS95895.1 - 0.0076 16.3 0.8 0.016 15.3 0.8 1.5 1 0 0 1 1 1 1 Basic region leucine zipper gag_pre-integrs PF13976.6 KXS95895.1 - 0.13 12.2 0.7 0.32 10.9 0.7 1.6 1 0 0 1 1 1 0 GAG-pre-integrase domain HAD_SAK_1 PF10307.9 KXS95897.1 - 2.6e-71 239.6 0.0 4.8e-71 238.8 0.0 1.4 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins PAN_4 PF14295.6 KXS95898.1 - 3.9e-05 23.5 1.0 3.9e-05 23.5 1.0 2.7 2 0 0 2 2 2 1 PAN domain Chitin_bind_1 PF00187.19 KXS95898.1 - 0.00059 20.3 21.0 0.00059 20.3 21.0 2.1 2 0 0 2 2 2 1 Chitin recognition protein CH PF00307.31 KXS95901.1 - 1e-08 35.3 0.0 0.00019 21.6 0.0 3.2 3 0 0 3 3 3 2 Calponin homology (CH) domain IQ PF00612.27 KXS95901.1 - 0.00024 20.6 0.8 0.98 9.4 0.0 2.9 2 0 0 2 2 2 2 IQ calmodulin-binding motif DUF5055 PF16478.5 KXS95901.1 - 0.059 13.6 0.0 0.21 11.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5055) CAMSAP_CH PF11971.8 KXS95901.1 - 0.19 11.6 0.0 19 5.1 0.1 3.2 3 1 0 3 3 3 0 CAMSAP CH domain Mito_carr PF00153.27 KXS95902.1 - 3e-53 177.7 2.4 2.8e-21 75.2 0.1 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein Aa_trans PF01490.18 KXS95903.1 - 6.2e-26 91.0 40.1 7.4e-26 90.8 40.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein IBV_3C PF03620.13 KXS95903.1 - 0.034 14.6 0.7 14 6.2 0.0 3.3 2 0 0 2 2 2 0 IBV 3C protein zf-H2C2 PF09337.10 KXS95904.1 - 3.9e-15 55.8 1.5 7.2e-15 54.9 1.5 1.5 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 KXS95904.1 - 2.2e-11 43.7 0.2 4.1e-11 42.8 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain Acetyltransf_1 PF00583.25 KXS95904.1 - 0.00049 20.3 0.0 0.00095 19.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 KXS95904.1 - 0.00057 20.1 0.0 0.0012 19.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KXS95904.1 - 0.01 16.5 0.1 0.33 11.6 0.0 2.4 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain PAN_4 PF14295.6 KXS95905.1 - 1.1e-22 79.7 6.9 1.3e-08 34.6 0.4 3.5 3 0 0 3 3 3 3 PAN domain PAN_1 PF00024.26 KXS95905.1 - 1.1e-10 41.3 6.4 0.0033 17.3 0.6 3.5 3 0 0 3 3 3 3 PAN domain PAN_2 PF08276.11 KXS95905.1 - 0.0016 18.6 9.3 0.39 10.9 0.4 3.7 3 0 0 3 3 3 3 PAN-like domain RHINO PF15319.6 KXS95905.1 - 0.37 10.8 6.1 0.9 9.5 6.1 1.6 1 0 0 1 1 1 0 RAD9, RAD1, HUS1-interacting nuclear orphan protein MFS_1 PF07690.16 KXS95906.1 - 8.6e-23 80.8 43.3 1.6e-20 73.4 36.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC2_membrane_5 PF13346.6 KXS95906.1 - 1.7 8.2 20.1 0.018 14.6 7.2 3.0 3 0 0 3 3 3 0 ABC-2 family transporter protein YccV-like PF08755.11 KXS95907.1 - 5.9e-29 100.5 1.3 9.8e-29 99.8 0.1 2.0 2 0 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.6 KXS95907.1 - 7e-12 45.2 1.1 1.2e-11 44.5 0.1 1.9 2 0 0 2 2 2 1 Transglutaminase-like superfamily F-box-like PF12937.7 KXS95907.1 - 1.7e-06 27.8 0.0 4.2e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS95907.1 - 1.7e-05 24.6 0.0 3.6e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 F-box domain Zn_clus PF00172.18 KXS95909.1 - 2.6e-10 40.2 8.3 4.5e-10 39.5 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TRIF-NTD PF17798.1 KXS95909.1 - 0.13 12.3 1.2 0.28 11.3 0.5 1.8 1 1 1 2 2 2 0 TRIF N-terminal domain DTW PF03942.15 KXS95909.1 - 2.4 7.8 6.9 0.1 12.3 0.5 1.9 2 1 0 2 2 2 0 DTW domain Mog1 PF04603.12 KXS95910.1 - 6e-39 133.6 0.0 7.3e-39 133.3 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein UBX PF00789.20 KXS95911.1 - 1.1e-10 41.6 0.0 2e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 UBX domain PEP_hydrolase PF09370.10 KXS95911.1 - 0.07 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate hydrolase-like dbPDZ_assoc PF16610.5 KXS95911.1 - 0.13 12.5 5.9 0.49 10.6 5.9 2.0 1 0 0 1 1 1 0 Unstructured region between two PDZ domains on Dlg5 MAJIN PF15077.6 KXS95911.1 - 3.2 7.5 10.7 7.6 6.2 10.7 1.6 1 0 0 1 1 1 0 Membrane-anchored junction protein DUF1682 PF07946.14 KXS95911.1 - 5.2 6.2 13.0 12 5.0 13.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) End3 PF12761.7 KXS95912.1 - 1.4e-76 257.1 5.3 2e-76 256.6 5.3 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.7 KXS95912.1 - 4e-49 164.9 0.1 2.4e-48 162.4 0.2 2.1 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 KXS95912.1 - 3.3e-08 32.5 0.2 8.4e-08 31.2 0.2 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KXS95912.1 - 7.4e-07 29.5 1.7 2.5e-06 27.8 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 KXS95912.1 - 6.2e-05 22.8 0.1 0.00018 21.3 0.1 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KXS95912.1 - 7.3e-05 22.4 1.2 0.00045 19.9 0.1 2.9 4 0 0 4 4 3 1 EF-hand domain EF-hand_5 PF13202.6 KXS95912.1 - 0.00083 18.7 0.1 0.0024 17.3 0.1 1.8 1 0 0 1 1 1 1 EF hand CSN5_C PF18323.1 KXS95912.1 - 0.02 15.8 4.2 0.065 14.2 4.1 2.0 1 1 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain EF-hand_11 PF08976.11 KXS95912.1 - 0.031 15.1 0.1 0.094 13.6 0.1 1.7 2 0 0 2 2 1 0 EF-hand domain Helo_like_N PF17111.5 KXS95912.1 - 0.28 10.5 1.6 8.7 5.6 0.1 2.2 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins EMP24_GP25L PF01105.24 KXS95912.1 - 0.29 11.0 1.5 8.3 6.3 0.0 2.2 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DHR10 PF18595.1 KXS95912.1 - 0.95 9.5 14.2 0.23 11.5 2.2 2.9 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain DUF16 PF01519.16 KXS95912.1 - 1.4 9.4 7.4 0.52 10.8 1.6 2.3 1 1 0 2 2 2 0 Protein of unknown function DUF16 Ax_dynein_light PF10211.9 KXS95912.1 - 2.3 8.2 11.1 0.53 10.2 2.8 2.2 1 1 1 2 2 2 0 Axonemal dynein light chain UPF0242 PF06785.11 KXS95912.1 - 2.5 8.2 7.1 4.6 7.3 7.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ADIP PF11559.8 KXS95912.1 - 6.1 6.9 11.3 2.2 8.3 2.8 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF641 PF04859.12 KXS95912.1 - 6.5 7.1 6.7 1.1 9.5 1.8 1.9 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) CC2-LZ PF16516.5 KXS95912.1 - 6.9 7.1 10.3 0.5 10.8 0.9 2.7 2 1 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator FlxA PF14282.6 KXS95912.1 - 6.9 6.7 9.1 15 5.6 1.4 2.5 1 1 0 2 2 2 0 FlxA-like protein Myb_DNA-bind_6 PF13921.6 KXS95913.1 - 2e-23 82.4 0.9 2.1e-06 27.9 0.0 4.8 4 1 1 5 5 5 4 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KXS95913.1 - 4.9e-21 74.7 2.6 0.0009 19.4 0.4 5.5 5 0 0 5 5 5 4 Myb-like DNA-binding domain Sigma70_r4_2 PF08281.12 KXS95913.1 - 1.8e-11 43.5 1.0 0.00073 19.2 0.0 4.7 5 0 0 5 5 5 2 Sigma-70, region 4 HTH_23 PF13384.6 KXS95913.1 - 5.8e-10 38.7 7.6 0.0047 16.7 0.0 5.9 6 0 0 6 6 6 2 Homeodomain-like domain HTH_38 PF13936.6 KXS95913.1 - 2.8e-09 36.6 0.6 0.13 12.1 0.0 4.6 4 0 0 4 4 4 2 Helix-turn-helix domain HTH_AsnC-type PF13404.6 KXS95913.1 - 7.9e-06 25.6 0.5 0.68 9.8 0.0 4.3 4 0 0 4 4 4 2 AsnC-type helix-turn-helix domain GcrA PF07750.11 KXS95913.1 - 4.3e-05 24.0 3.1 0.49 10.8 0.0 3.3 2 1 1 3 3 3 2 GcrA cell cycle regulator HTH_29 PF13551.6 KXS95913.1 - 0.00011 22.2 1.7 4.9 7.3 0.0 4.8 5 2 1 6 6 6 1 Winged helix-turn helix HTH_7 PF02796.15 KXS95913.1 - 0.0045 17.0 0.7 9.6 6.4 0.0 4.0 4 0 0 4 4 4 1 Helix-turn-helix domain of resolvase GerE PF00196.19 KXS95913.1 - 0.0059 16.1 0.0 3.1 7.4 0.0 3.1 3 0 0 3 3 3 1 Bacterial regulatory proteins, luxR family HTH_11 PF08279.12 KXS95913.1 - 0.013 15.4 1.5 13 5.9 0.1 3.7 4 1 0 4 4 4 0 HTH domain HTH_24 PF13412.6 KXS95913.1 - 0.018 14.6 0.2 21 4.8 0.0 4.2 5 0 0 5 5 5 0 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 KXS95913.1 - 0.14 12.3 3.5 46 4.2 0.0 4.5 5 0 0 5 5 5 0 Helix-turn-helix domain DUF5131 PF07505.11 KXS95914.1 - 0.0018 17.8 0.0 0.0044 16.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF5131) FAM184 PF15665.5 KXS95914.1 - 0.011 15.6 14.3 0.011 15.6 14.3 2.8 2 1 1 3 3 3 0 Family with sequence similarity 184, A and B WXG100 PF06013.12 KXS95914.1 - 0.045 14.0 0.6 0.045 14.0 0.6 3.7 3 1 1 4 4 4 0 Proteins of 100 residues with WXG Glyco_hydro_65m PF03632.15 KXS95914.1 - 0.17 10.7 6.6 0.27 10.0 6.6 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65 central catalytic domain Perilipin PF03036.16 KXS95914.1 - 0.52 9.3 15.6 0.083 11.9 5.5 2.4 1 1 1 2 2 2 0 Perilipin family MogR_DNAbind PF12181.8 KXS95915.1 - 0.068 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 DNA binding domain of the motility gene repressor (MogR) FMN_dh PF01070.18 KXS95916.1 - 1.1e-103 346.9 1.0 1.9e-103 346.2 1.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase FMO-like PF00743.19 KXS95916.1 - 7.3e-70 235.9 0.0 1.6e-69 234.7 0.0 1.5 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like p450 PF00067.22 KXS95916.1 - 2.2e-62 211.3 0.0 3.1e-62 210.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Cyt-b5 PF00173.28 KXS95916.1 - 3.4e-17 62.4 0.0 7.8e-17 61.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pyr_redox_3 PF13738.6 KXS95916.1 - 9.6e-16 57.9 0.0 4.7e-13 49.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXS95916.1 - 1.1e-09 37.9 0.0 6.8e-09 35.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXS95916.1 - 1.2e-06 28.0 0.0 3.6e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) IlvN PF07991.12 KXS95916.1 - 5e-05 22.9 0.0 0.43 10.1 0.0 2.7 2 0 0 2 2 2 2 Acetohydroxy acid isomeroreductase, NADPH-binding domain ThiF PF00899.21 KXS95916.1 - 0.0052 16.2 0.1 0.27 10.6 0.1 2.5 2 0 0 2 2 2 1 ThiF family IMPDH PF00478.25 KXS95916.1 - 0.021 13.8 0.2 0.064 12.3 0.2 1.7 1 1 1 2 2 2 0 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KXS95916.1 - 0.038 13.4 0.7 0.065 12.6 0.7 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase Glu_synthase PF01645.17 KXS95916.1 - 0.039 13.1 0.0 0.069 12.3 0.0 1.3 1 0 0 1 1 1 0 Conserved region in glutamate synthase NAD_binding_8 PF13450.6 KXS95916.1 - 0.043 14.0 0.0 0.16 12.3 0.0 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ThiG PF05690.14 KXS95916.1 - 0.051 12.9 0.3 0.6 9.4 0.1 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Peptidase_M17_N PF02789.17 KXS95916.1 - 0.15 11.9 0.9 21 5.0 0.0 2.5 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain Tannase PF07519.11 KXS95917.1 - 2.6e-112 376.1 0.9 3.2e-112 375.8 0.9 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_1 PF00561.20 KXS95917.1 - 0.011 15.4 0.1 0.028 14.1 0.1 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXS95917.1 - 0.071 12.4 0.0 0.23 10.7 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 MFS_1 PF07690.16 KXS95918.1 - 2.9e-16 59.4 33.7 1.2e-15 57.4 27.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 KXS95918.1 - 6.5e-05 22.7 4.8 6.5e-05 22.7 4.8 2.3 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 PUCC PF03209.15 KXS95918.1 - 0.019 14.0 4.6 0.043 12.8 4.6 1.7 1 0 0 1 1 1 0 PUCC protein DUF4257 PF14074.6 KXS95918.1 - 0.099 12.9 0.0 0.31 11.3 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4257) SIP1 PF04938.12 KXS95919.1 - 4.8e-14 52.6 0.1 3.1e-12 46.7 0.0 2.2 2 0 0 2 2 2 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) NUP50 PF08911.11 KXS95919.1 - 0.64 10.7 4.1 3.3 8.4 0.2 2.9 2 1 1 3 3 3 0 NUP50 (Nucleoporin 50 kDa) Peptidase_M20 PF01546.28 KXS95920.1 - 2.8e-17 63.1 0.0 5.2e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KXS95920.1 - 8.5e-13 48.2 0.1 1.8e-12 47.1 0.1 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain DAO PF01266.24 KXS95921.1 - 2.1e-33 116.4 0.5 2.6e-33 116.0 0.5 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXS95921.1 - 0.0026 17.9 0.0 0.0054 16.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXS95921.1 - 0.0063 15.8 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 KXS95921.1 - 0.049 12.7 0.0 0.36 9.8 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.14 KXS95921.1 - 0.065 12.5 0.0 0.23 10.6 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXS95921.1 - 0.088 12.0 0.0 0.35 10.1 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HSP70 PF00012.20 KXS95922.1 - 2.6e-07 29.2 0.0 5e-07 28.3 0.0 1.4 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 KXS95922.1 - 0.0011 17.9 0.0 0.67 8.7 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein StbA PF06406.11 KXS95922.1 - 0.055 12.7 0.0 4.7 6.4 0.0 2.2 2 0 0 2 2 2 0 StbA protein ZapB PF06005.12 KXS95923.1 - 0.0089 16.4 4.5 0.018 15.5 4.5 1.4 1 0 0 1 1 1 1 Cell division protein ZapB NUDE_C PF04880.13 KXS95923.1 - 0.021 15.3 0.6 0.042 14.3 0.6 1.4 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region HAUS-augmin3 PF14932.6 KXS95923.1 - 0.36 10.4 2.2 0.65 9.5 2.2 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DSPc PF00782.20 KXS95925.1 - 2e-10 40.6 0.1 3.5e-10 39.8 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KXS95925.1 - 0.0021 18.3 0.0 0.0043 17.3 0.0 1.5 1 0 0 1 1 1 1 Rit1 DUSP-like domain Ribosomal_L1 PF00687.21 KXS95926.1 - 1.2e-63 214.6 1.4 2.5e-63 213.5 1.0 1.7 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family Methyltransf_31 PF13847.6 KXS95927.1 - 1.1e-21 77.3 0.0 1.6e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS95927.1 - 2.6e-21 76.1 0.0 3.8e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS95927.1 - 4.1e-19 69.0 0.0 5.8e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXS95927.1 - 7.8e-13 48.3 0.0 1.1e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KXS95927.1 - 1.2e-12 48.4 0.0 2e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXS95927.1 - 3.7e-08 33.1 0.0 5e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KXS95927.1 - 8.4e-08 31.9 0.0 1.4e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.6 KXS95927.1 - 1.8e-06 27.9 0.0 2.3e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KXS95927.1 - 3.6e-05 23.8 0.2 5.3e-05 23.3 0.0 1.4 2 0 0 2 2 1 1 Methyltransferase domain MetW PF07021.12 KXS95927.1 - 4.3e-05 23.2 0.0 6.1e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PrmA PF06325.13 KXS95927.1 - 0.00015 21.3 0.0 0.00021 20.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 KXS95927.1 - 0.0004 20.2 0.0 0.00049 19.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TPMT PF05724.11 KXS95927.1 - 0.0016 18.2 0.0 0.0023 17.6 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) CMAS PF02353.20 KXS95927.1 - 0.0048 16.2 0.0 0.0064 15.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase tRNA_U5-meth_tr PF05958.11 KXS95927.1 - 0.01 14.8 0.0 0.014 14.4 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase NodS PF05401.11 KXS95927.1 - 0.023 14.3 0.0 0.03 13.9 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_18 PF12847.7 KXS95927.1 - 0.025 14.5 0.0 0.048 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF2332 PF10094.9 KXS95927.1 - 0.029 13.8 0.0 0.036 13.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2332) Methyltransf_15 PF09445.10 KXS95927.1 - 0.06 12.9 0.0 0.084 12.4 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_2 PF00891.18 KXS95927.1 - 0.1 11.9 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain CheR PF01739.18 KXS95927.1 - 0.12 11.8 0.0 1.5 8.2 0.0 2.1 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Pox_MCEL PF03291.16 KXS95927.1 - 0.13 11.3 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 mRNA capping enzyme PhoLip_ATPase_C PF16212.5 KXS95928.1 - 2.4e-54 184.7 2.1 2.4e-54 184.7 2.1 1.8 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KXS95928.1 - 4.7e-17 61.4 0.4 9.8e-17 60.4 0.4 1.5 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KXS95928.1 - 1.9e-13 51.2 1.6 2.8e-07 31.0 0.7 3.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KXS95928.1 - 2.6e-08 33.6 1.6 0.0022 17.6 0.0 2.5 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase PF13246.6 KXS95928.1 - 8.2e-07 29.0 0.0 1.5e-05 24.9 0.0 2.8 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KXS95928.1 - 0.0042 16.9 0.0 0.0088 15.8 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HIGH_NTase1_ass PF16581.5 KXS95928.1 - 0.17 11.8 0.0 0.3 11.1 0.0 1.2 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Phage_Coat_B PF05356.11 KXS95928.1 - 0.67 9.9 2.4 0.99 9.4 0.0 2.6 3 0 0 3 3 3 0 Phage Coat protein B WD40 PF00400.32 KXS95929.1 - 2.1e-13 50.5 0.3 1.3e-07 32.2 0.0 5.3 4 1 1 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS95929.1 - 5.4e-05 23.4 0.0 2.4 8.5 0.0 4.1 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Herpes_UL37_1 PF03970.13 KXS95929.1 - 0.00055 19.2 0.0 0.0008 18.7 0.0 1.2 1 0 0 1 1 1 1 Herpesvirus UL37 tegument protein Carn_acyltransf PF00755.20 KXS95930.1 - 2.2e-210 700.3 0.0 3.2e-210 699.7 0.0 1.3 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Glyco_hydro_43 PF04616.14 KXS95931.1 - 4e-36 124.8 0.0 5.3e-36 124.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Sec16_C PF12931.7 KXS95932.1 - 4.9e-97 325.2 0.5 7e-97 324.7 0.5 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 KXS95932.1 - 4e-28 98.4 0.0 1.3e-27 96.7 0.0 2.0 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Abhydrolase_3 PF07859.13 KXS95933.1 - 2.8e-65 220.1 0.0 3.6e-65 219.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXS95933.1 - 2.8e-07 29.8 0.3 4.1e-06 25.9 0.0 2.0 2 0 0 2 2 2 1 Carboxylesterase family Peptidase_S9 PF00326.21 KXS95933.1 - 5.8e-07 29.2 0.0 9.9e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 KXS95933.1 - 1.6e-06 27.3 0.0 2.1e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Say1_Mug180 PF10340.9 KXS95933.1 - 1.1e-05 24.5 0.0 1.7e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Chlorophyllase PF07224.11 KXS95933.1 - 1.3e-05 24.4 0.0 1.8e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Esterase PF00756.20 KXS95933.1 - 0.0018 18.0 0.6 0.012 15.3 0.6 2.0 1 1 0 1 1 1 1 Putative esterase Esterase_phd PF10503.9 KXS95933.1 - 0.023 14.2 0.6 0.049 13.1 0.5 1.6 1 1 0 1 1 1 0 Esterase PHB depolymerase Thioesterase PF00975.20 KXS95933.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.5 2 0 0 2 2 2 0 Thioesterase domain Rad51 PF08423.11 KXS95934.1 - 8.2e-44 149.8 0.0 1.2e-43 149.3 0.0 1.2 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 KXS95934.1 - 7.3e-09 35.5 0.1 1.5e-05 24.6 0.0 2.1 2 0 0 2 2 2 2 recA bacterial DNA recombination protein AAA_25 PF13481.6 KXS95934.1 - 3.4e-07 30.0 0.3 8.3e-07 28.8 0.3 1.6 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 KXS95934.1 - 7.3e-07 28.8 0.1 3.1e-06 26.7 0.1 1.9 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 KXS95934.1 - 0.0018 17.7 0.2 0.08 12.3 0.2 2.3 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 KXS95934.1 - 0.04 14.2 0.1 0.11 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KXS95934.1 - 0.049 13.4 0.0 0.078 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Rad51 PF08423.11 KXS95935.1 - 8.2e-44 149.8 0.0 1.2e-43 149.3 0.0 1.2 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 KXS95935.1 - 7.3e-09 35.5 0.1 1.5e-05 24.6 0.0 2.1 2 0 0 2 2 2 2 recA bacterial DNA recombination protein AAA_25 PF13481.6 KXS95935.1 - 3.4e-07 30.0 0.3 8.3e-07 28.8 0.3 1.6 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 KXS95935.1 - 7.3e-07 28.8 0.1 3.1e-06 26.7 0.1 1.9 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 KXS95935.1 - 0.0018 17.7 0.2 0.08 12.3 0.2 2.3 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 KXS95935.1 - 0.04 14.2 0.1 0.11 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KXS95935.1 - 0.049 13.4 0.0 0.078 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain SGL PF08450.12 KXS95938.1 - 1.3e-05 24.9 0.0 1.9e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region SGL PF08450.12 KXS95940.1 - 6.7e-37 127.4 0.0 8e-37 127.1 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Cullin_binding PF03556.15 KXS95941.1 - 0.019 15.4 1.3 0.05 14.1 0.4 2.1 2 0 0 2 2 2 0 Cullin binding Syntaxin_2 PF14523.6 KXS95941.1 - 0.75 10.2 2.9 2.9 8.3 0.4 2.8 3 1 0 3 3 3 0 Syntaxin-like protein Lung_7-TM_R PF06814.13 KXS95942.1 - 1.1e-66 225.2 23.2 1.3e-66 224.9 23.2 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor WD40 PF00400.32 KXS95943.1 - 6.9e-14 52.0 13.7 1.3e-05 25.9 0.1 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 KXS95943.1 - 1.3e-13 51.0 0.1 3.8e-13 49.5 0.0 1.9 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 KXS95943.1 - 7.7e-07 29.3 1.9 0.0038 17.5 0.1 3.4 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain ELYS-bb PF16687.5 KXS95943.1 - 0.12 10.9 0.0 0.19 10.3 0.0 1.1 1 0 0 1 1 1 0 beta-propeller of ELYS nucleoporin Mito_carr PF00153.27 KXS95944.1 - 1.7e-52 175.3 2.6 7.8e-18 64.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ras PF00071.22 KXS95945.1 - 2.5e-31 108.5 0.2 3.4e-31 108.0 0.2 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXS95945.1 - 9.5e-24 83.9 0.1 1.7e-23 83.1 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXS95945.1 - 6.9e-07 28.9 0.1 8.8e-07 28.5 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KXS95945.1 - 0.00012 21.5 0.2 0.00017 21.0 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 KXS95945.1 - 0.013 14.4 0.1 1.7 7.4 0.0 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) G-alpha PF00503.20 KXS95945.1 - 0.093 11.9 2.4 0.43 9.7 0.1 2.4 1 1 1 3 3 3 0 G-protein alpha subunit RA PF00788.23 KXS95946.1 - 1.6e-12 47.9 0.0 3.2e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_2 PF07647.17 KXS95946.1 - 1e-11 44.8 0.0 1.9e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KXS95946.1 - 2.7e-10 40.5 0.0 4.8e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_4 PF18017.1 KXS95946.1 - 0.0045 16.9 0.0 0.0084 16.1 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KXS95946.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain RNA_pol_Rpb1_R PF05001.13 KXS95946.1 - 0.69 10.4 8.5 0.32 11.4 2.8 3.7 2 0 0 2 2 2 0 RNA polymerase Rpb1 C-terminal repeat UNC-93 PF05978.16 KXS95947.1 - 7.1e-15 55.1 7.2 2e-14 53.6 7.2 1.8 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 KXS95947.1 - 5.5e-11 42.0 35.4 5.5e-11 42.0 35.4 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4231 PF14015.6 KXS95947.1 - 0.13 12.7 4.1 0.14 12.7 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) DUF4112 PF13430.6 KXS95948.1 - 2e-35 121.2 0.3 2.6e-35 120.8 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) SKN1 PF03935.15 KXS95950.1 - 4e-220 731.4 7.6 4.9e-220 731.1 7.6 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) DUF4456 PF14644.6 KXS95950.1 - 0.082 12.6 0.8 0.15 11.7 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) Fcf1 PF04900.12 KXS95954.1 - 6.5e-36 122.7 1.0 2e-35 121.2 0.5 1.9 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 KXS95954.1 - 1.8e-13 50.8 1.2 1.7e-11 44.4 0.0 2.1 2 0 0 2 2 2 2 PIN like domain GCV_T PF01571.21 KXS95954.1 - 0.02 14.3 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Aminomethyltransferase folate-binding domain DUF4706 PF15797.5 KXS95954.1 - 0.089 13.3 0.4 0.59 10.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4706) Lactonase PF10282.9 KXS95955.1 - 2.5e-16 59.9 0.0 3.2e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Arylesterase PF01731.20 KXS95955.1 - 0.07 13.3 0.0 0.22 11.8 0.0 1.9 2 0 0 2 2 2 0 Arylesterase Pribosyltran_N PF13793.6 KXS95956.1 - 0.13 12.2 0.1 0.28 11.1 0.1 1.5 1 0 0 1 1 1 0 N-terminal domain of ribose phosphate pyrophosphokinase MutS_V PF00488.21 KXS95957.1 - 2.5e-76 255.9 0.1 5.6e-76 254.8 0.1 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KXS95957.1 - 1.1e-35 123.6 2.0 1.1e-35 123.6 2.0 2.0 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 KXS95957.1 - 4.5e-28 97.8 0.0 1.2e-27 96.4 0.0 1.8 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 KXS95957.1 - 1.7e-08 34.8 0.0 6.6e-08 32.9 0.0 2.1 1 0 0 1 1 1 1 MutS domain II DUF397 PF04149.12 KXS95958.1 - 0.13 12.3 0.8 0.22 11.6 0.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF397) eIF3_subunit PF08597.10 KXS95960.1 - 8.9e-73 245.2 32.8 1.1e-72 244.9 32.8 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit DehI PF10778.9 KXS95960.1 - 0.1 12.8 0.1 0.1 12.8 0.1 1.9 2 0 0 2 2 2 0 Halocarboxylic acid dehydrogenase DehI DUF1877 PF08974.10 KXS95960.1 - 6.9 6.7 11.3 94 3.0 11.4 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1877) IHABP4_N PF16174.5 KXS95960.1 - 7.4 7.1 27.7 0.2 12.3 15.1 2.4 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal Methyltransf_23 PF13489.6 KXS95961.1 - 4.1e-11 43.0 0.0 6.4e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS95961.1 - 1.2e-10 41.4 0.0 1.6e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS95961.1 - 6.6e-10 39.6 0.0 1.2e-09 38.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS95961.1 - 2.9e-08 34.4 0.0 5.6e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS95961.1 - 6.9e-07 29.8 0.0 1.4e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXS95961.1 - 0.0016 18.0 0.0 0.0031 17.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 KXS95961.1 - 0.0019 18.3 0.0 0.0027 17.8 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase CheR PF01739.18 KXS95961.1 - 0.0034 16.9 0.0 0.16 11.5 0.0 2.2 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain Ubie_methyltran PF01209.18 KXS95961.1 - 0.0039 16.6 0.0 0.013 14.8 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family pPIWI_RE_Y PF18156.1 KXS95961.1 - 0.019 15.4 0.2 0.091 13.2 0.2 1.9 2 0 0 2 2 2 0 pPIWI_RE three-gene island domain Y RhoGAP PF00620.27 KXS95962.1 - 5.8e-16 58.7 0.0 1.1e-15 57.8 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 KXS95962.1 - 3.1e-11 43.4 0.1 8.1e-11 42.0 0.1 1.8 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.21 KXS95962.1 - 1.5e-10 41.0 0.0 3e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) YTH PF04146.15 KXS95963.1 - 5.8e-62 208.5 0.0 1e-61 207.7 0.0 1.4 1 0 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.22 KXS95963.1 - 1.4e-07 31.2 0.0 2.5e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_4 PF13894.6 KXS95965.1 - 2.4e-06 27.9 10.7 0.042 14.7 0.3 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 KXS95965.1 - 3.7e-06 27.1 13.6 0.0059 17.0 0.7 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KXS95965.1 - 9e-06 25.6 3.2 0.0057 16.6 0.0 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KXS95965.1 - 0.0057 16.9 0.9 3.5 8.0 0.0 2.2 2 0 0 2 2 2 2 C2H2-type zinc ribbon zinc_ribbon_5 PF13719.6 KXS95965.1 - 0.019 14.7 4.2 0.069 12.9 0.3 2.7 2 1 0 2 2 2 0 zinc-ribbon domain C1_4 PF07975.12 KXS95965.1 - 0.063 13.5 5.5 0.62 10.3 0.2 2.5 2 1 0 2 2 2 0 TFIIH C1-like domain NADH-G_4Fe-4S_3 PF10588.9 KXS95965.1 - 0.084 12.4 0.6 0.084 12.4 0.6 2.4 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Rad50_zn_hook PF04423.14 KXS95965.1 - 0.27 11.1 2.4 8.3 6.3 0.4 3.1 3 0 0 3 3 3 0 Rad50 zinc hook motif Mucin PF01456.17 KXS95966.1 - 0.99 9.4 30.8 0.12 12.3 26.6 1.6 2 0 0 2 2 2 0 Mucin-like glycoprotein MVL PF12151.8 KXS95968.1 - 0.095 12.6 0.7 0.18 11.7 0.7 1.4 1 0 0 1 1 1 0 Mannan-binding protein Formyl_trans_N PF00551.19 KXS95969.1 - 4.2e-40 137.4 0.0 5.2e-40 137.1 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase DUF4047 PF13256.6 KXS95970.1 - 0.0081 16.4 9.0 0.29 11.3 3.8 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4047) DUF4460 PF14687.6 KXS95970.1 - 0.038 14.0 5.9 0.043 13.9 4.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4460) NACHT PF05729.12 KXS95972.1 - 1.2e-11 44.8 0.1 3.3e-11 43.4 0.1 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KXS95972.1 - 8.9e-05 22.9 0.1 0.00034 21.1 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 KXS95972.1 - 0.0058 15.8 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 KXS95972.1 - 0.0075 16.5 0.0 0.027 14.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KXS95972.1 - 0.055 13.9 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Viral_helicase1 PF01443.18 KXS95972.1 - 0.055 13.2 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RsgA_GTPase PF03193.16 KXS95972.1 - 0.06 13.3 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase ATPase_2 PF01637.18 KXS95972.1 - 0.067 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_29 PF13555.6 KXS95972.1 - 0.074 12.8 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ploopntkinase3 PF18751.1 KXS95972.1 - 0.078 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 ABC_tran PF00005.27 KXS95972.1 - 0.093 13.2 0.0 0.19 12.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_30 PF13604.6 KXS95972.1 - 0.16 11.7 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Nucleic_acid_bd PF13820.6 KXS95973.1 - 0.22 11.3 0.0 0.41 10.5 0.0 1.4 1 1 0 1 1 1 0 Putative nucleic acid-binding region SET PF00856.28 KXS95976.1 - 6.9e-10 39.6 0.0 2.7e-09 37.6 0.0 1.9 1 1 0 1 1 1 1 SET domain Cpn60_TCP1 PF00118.24 KXS95977.1 - 1.8e-140 468.8 10.9 2.1e-140 468.6 10.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 KXS95977.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat Ldl_recept_b PF00058.17 KXS95977.1 - 0.16 12.5 0.0 0.49 10.9 0.0 1.9 1 0 0 1 1 1 0 Low-density lipoprotein receptor repeat class B DUF5442 PF17514.2 KXS95977.1 - 0.19 12.0 0.1 0.4 10.9 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5442) FlgM PF04316.13 KXS95977.1 - 1.3 9.5 4.2 2.2 8.7 0.0 3.3 3 0 0 3 3 3 0 Anti-sigma-28 factor, FlgM ATP11 PF06644.11 KXS95978.1 - 6.3e-98 327.9 0.6 7.2e-98 327.7 0.6 1.0 1 0 0 1 1 1 1 ATP11 protein CAGE1 PF15066.6 KXS95978.1 - 0.28 9.8 3.5 0.58 8.8 2.0 1.9 2 0 0 2 2 2 0 Cancer-associated gene protein 1 family RRS1 PF04939.12 KXS95979.1 - 2.1e-43 148.0 1.3 2.3e-43 147.8 1.3 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) RRS1 PF04939.12 KXS95980.1 - 2.1e-43 148.0 1.3 2.3e-43 147.8 1.3 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) WW PF00397.26 KXS95984.1 - 1.1e-10 41.4 0.6 2.7e-10 40.1 0.6 1.8 1 0 0 1 1 1 1 WW domain PhoD PF09423.10 KXS95984.1 - 0.085 11.9 0.0 0.24 10.4 0.0 1.7 1 0 0 1 1 1 0 PhoD-like phosphatase Fib_alpha PF08702.10 KXS95985.1 - 0.22 11.7 0.7 0.96 9.6 0.4 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF2357 PF09823.9 KXS95985.1 - 0.34 10.1 2.9 0.56 9.4 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2357) HisG PF01634.18 KXS95986.1 - 4.4e-56 189.3 0.1 6.1e-56 188.8 0.1 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 KXS95986.1 - 3.8e-29 100.7 0.3 7.5e-29 99.7 0.3 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain Methyltrans_RNA PF04452.14 KXS95986.1 - 0.037 13.3 0.1 0.057 12.7 0.1 1.3 1 0 0 1 1 1 0 RNA methyltransferase NMT1 PF09084.11 KXS95986.1 - 0.052 13.5 0.2 0.11 12.4 0.2 1.5 1 1 0 1 1 1 0 NMT1/THI5 like DEAD PF00270.29 KXS95987.1 - 6.8e-49 166.0 0.0 1.4e-48 165.0 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXS95987.1 - 1.9e-31 108.7 0.0 4.3e-31 107.5 0.0 1.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXS95987.1 - 0.0058 16.6 0.0 0.0099 15.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KXS95987.1 - 0.049 13.0 0.0 0.085 12.2 0.0 1.2 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF2797 PF10977.8 KXS95988.1 - 1.3 8.8 6.1 2.6 7.9 6.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) Zn_clus PF00172.18 KXS95988.1 - 4.3 7.5 20.6 0.25 11.5 6.3 2.5 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5560 PF17715.1 KXS95989.1 - 0.19 11.2 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5560) GMC_oxred_N PF00732.19 KXS95991.1 - 2e-34 119.3 0.0 2.8e-34 118.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXS95991.1 - 1.1e-14 55.2 0.0 2.6e-14 53.9 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KXS95991.1 - 8.1e-09 35.0 0.5 2.8e-06 26.7 0.4 2.2 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 KXS95991.1 - 7.6e-06 24.9 0.1 2.9e-05 22.9 0.2 1.9 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 KXS95991.1 - 1e-05 24.9 0.0 0.00034 19.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXS95991.1 - 1.2e-05 24.9 0.1 6e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KXS95991.1 - 2.7e-05 23.6 0.0 4.3e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXS95991.1 - 4e-05 23.8 0.0 0.00011 22.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXS95991.1 - 0.0001 22.0 0.0 0.012 15.2 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXS95991.1 - 0.00039 19.8 0.7 0.0051 16.1 0.4 2.5 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXS95991.1 - 0.00046 19.4 0.1 0.001 18.2 0.1 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KXS95991.1 - 0.0013 17.9 0.0 0.0021 17.2 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KXS95991.1 - 0.002 17.4 0.0 0.0073 15.6 0.0 1.8 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 KXS95991.1 - 0.19 12.3 0.4 3.2 8.4 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_S28e PF01200.18 KXS95992.1 - 3.5e-31 107.0 2.3 3.9e-31 106.8 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e IBR PF01485.21 KXS95993.1 - 7.5e-10 38.9 50.6 4.9e-06 26.7 4.2 4.9 4 1 0 4 4 4 3 IBR domain, a half RING-finger domain Methyltransf_25 PF13649.6 KXS95994.1 - 3.4e-05 24.5 0.0 8.6e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS95994.1 - 0.00095 19.0 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain APC_u14 PF16635.5 KXS95994.1 - 0.088 13.4 0.1 0.23 12.0 0.1 1.7 1 0 0 1 1 1 0 Unstructured region on APC between SAMP and APC_crr Glyco_hydro_63 PF03200.16 KXS96002.1 - 2.4e-168 560.9 4.0 4.4e-167 556.7 4.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 KXS96002.1 - 1.3e-83 280.6 0.1 6.8e-83 278.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 KXS96002.1 - 4.9e-06 25.7 0.5 8.2e-06 24.9 0.5 1.3 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.14 KXS96002.1 - 0.00096 18.2 0.3 0.0018 17.3 0.3 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Bac_rhamnosid6H PF17389.2 KXS96002.1 - 0.016 14.5 0.2 0.07 12.4 0.0 2.0 2 0 0 2 2 2 0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Glyco_hydro_63 PF03200.16 KXS96003.1 - 2.4e-168 560.9 4.0 4.4e-167 556.7 4.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 KXS96003.1 - 1.3e-83 280.6 0.1 6.8e-83 278.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 KXS96003.1 - 4.9e-06 25.7 0.5 8.2e-06 24.9 0.5 1.3 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.14 KXS96003.1 - 0.00096 18.2 0.3 0.0018 17.3 0.3 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Bac_rhamnosid6H PF17389.2 KXS96003.1 - 0.016 14.5 0.2 0.07 12.4 0.0 2.0 2 0 0 2 2 2 0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain MFS_1 PF07690.16 KXS96004.1 - 3.8e-36 124.7 25.7 3.8e-36 124.7 25.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily OSTbeta PF15048.6 KXS96004.1 - 0.031 14.4 0.1 0.11 12.7 0.0 1.9 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein DUF1230 PF06799.11 KXS96004.1 - 0.84 9.7 3.2 2 8.5 0.0 3.0 4 0 0 4 4 4 0 Conserved in the green lineage and diatoms 27 Porphobil_deam PF01379.20 KXS96005.1 - 3.1e-78 262.0 0.2 6.5e-78 260.9 0.2 1.6 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 KXS96005.1 - 2.3e-17 63.1 0.3 3.4e-10 40.2 0.0 2.6 2 0 0 2 2 2 2 Porphobilinogen deaminase, C-terminal domain Peptidase_S10 PF00450.22 KXS96005.1 - 0.079 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase TMEM215 PF15746.5 KXS96005.1 - 0.098 12.1 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 TMEM215 family ACT_6 PF13740.6 KXS96005.1 - 0.11 12.5 0.0 0.57 10.2 0.0 2.1 2 0 0 2 2 2 0 ACT domain NolV PF06635.12 KXS96007.1 - 0.0071 15.7 0.1 0.011 15.1 0.1 1.3 1 0 0 1 1 1 1 Nodulation protein NolV Suc_Fer-like PF06999.12 KXS96008.1 - 2.1e-60 204.0 0.0 2.4e-60 203.7 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Iso_dh PF00180.20 KXS96009.1 - 3.8e-99 332.1 0.0 4.6e-99 331.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phage_30_3 PF08010.11 KXS96009.1 - 0.0067 16.2 0.1 0.017 14.9 0.0 1.7 2 0 0 2 2 2 1 Bacteriophage protein GP30.3 IF4E PF01652.18 KXS96010.1 - 1.3e-41 142.1 0.3 1.6e-41 141.7 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E MMtag PF10159.9 KXS96011.1 - 2.3e-31 107.9 2.1 2.3e-31 107.9 2.1 2.0 2 0 0 2 2 2 1 Multiple myeloma tumor-associated TAF4 PF05236.14 KXS96011.1 - 0.078 12.7 6.0 0.1 12.3 6.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Nop14 PF04147.12 KXS96011.1 - 3.5 5.7 11.2 4.9 5.2 11.2 1.1 1 0 0 1 1 1 0 Nop14-like family LSM PF01423.22 KXS96013.1 - 2.5e-17 62.3 0.0 3.5e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KXS96013.1 - 0.011 15.8 0.0 0.017 15.2 0.0 1.5 1 1 0 1 1 1 0 Ataxin 2 SM domain API5 PF05918.11 KXS96013.1 - 5.2 5.8 11.0 6.3 5.5 11.0 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) ORC5_C PF14630.6 KXS96014.1 - 9.3e-74 248.5 0.0 1.2e-73 248.2 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 KXS96014.1 - 6.9e-15 55.8 0.1 4.1e-14 53.3 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KXS96014.1 - 4.4e-05 23.8 0.0 9.3e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KXS96014.1 - 0.032 14.1 0.0 0.097 12.6 0.0 1.8 1 0 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 KXS96014.1 - 0.043 13.7 0.0 0.074 12.9 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TniB PF05621.11 KXS96014.1 - 0.076 12.4 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein DUF1381 PF07129.11 KXS96014.1 - 0.16 11.8 0.1 0.37 10.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1381) MFS_1 PF07690.16 KXS96015.1 - 7.8e-28 97.4 59.2 1.5e-25 89.9 60.0 3.5 2 1 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 KXS96015.1 - 0.002 16.5 0.9 0.002 16.5 0.9 3.4 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family RIBIOP_C PF04950.12 KXS96016.1 - 5.6e-96 321.4 0.2 5.6e-96 321.4 0.2 2.1 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KXS96016.1 - 4.2e-28 97.3 0.0 1.3e-27 95.6 0.0 2.0 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_33 PF13671.6 KXS96016.1 - 9.2e-05 22.6 0.0 0.00043 20.5 0.0 2.3 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 KXS96016.1 - 9.5e-05 22.0 0.3 0.036 13.6 0.0 2.9 2 1 1 3 3 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KXS96016.1 - 0.00021 21.6 0.0 0.00063 20.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KXS96016.1 - 0.00037 20.6 0.0 0.0012 18.9 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.29 KXS96016.1 - 0.00048 20.6 0.0 0.0012 19.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXS96016.1 - 0.00058 20.3 0.0 0.00058 20.3 0.0 2.2 2 1 0 2 2 1 1 AAA ATPase domain NB-ARC PF00931.22 KXS96016.1 - 0.0029 16.8 0.0 0.0068 15.6 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain ABC_tran PF00005.27 KXS96016.1 - 0.0035 17.9 0.2 0.024 15.1 0.0 2.5 2 0 0 2 2 1 1 ABC transporter AAA_19 PF13245.6 KXS96016.1 - 0.0039 17.5 0.0 0.01 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXS96016.1 - 0.0087 16.6 0.1 0.0087 16.6 0.1 3.6 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 KXS96016.1 - 0.01 15.8 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain cobW PF02492.19 KXS96016.1 - 0.02 14.5 0.1 0.041 13.5 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KXS96016.1 - 0.024 14.4 0.0 0.054 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 KXS96016.1 - 0.024 13.6 0.0 0.064 12.2 0.0 1.6 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TsaE PF02367.17 KXS96016.1 - 0.044 13.8 0.0 0.55 10.2 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KXS96016.1 - 0.048 14.0 0.1 0.14 12.5 0.0 1.8 2 0 0 2 2 1 0 RNA helicase Roc PF08477.13 KXS96016.1 - 0.05 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase KAP_NTPase PF07693.14 KXS96016.1 - 0.054 12.7 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 KAP family P-loop domain RsgA_GTPase PF03193.16 KXS96016.1 - 0.055 13.4 0.6 0.21 11.5 0.0 2.2 3 0 0 3 3 3 0 RsgA GTPase NTPase_1 PF03266.15 KXS96016.1 - 0.065 13.2 0.3 0.15 11.9 0.3 1.6 1 0 0 1 1 1 0 NTPase Rad17 PF03215.15 KXS96016.1 - 0.075 13.0 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 Rad17 P-loop domain Wzy_C_2 PF11846.8 KXS96016.1 - 0.082 12.8 0.4 0.15 12.0 0.4 1.4 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal AAA_5 PF07728.14 KXS96016.1 - 0.12 12.4 0.2 0.41 10.6 0.0 2.0 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) MobB PF03205.14 KXS96016.1 - 0.13 12.1 0.1 0.58 10.1 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_7 PF12775.7 KXS96016.1 - 0.14 11.6 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 KXS96016.1 - 0.15 11.8 0.0 1.4 8.7 0.0 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 KXS96016.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 KXS96017.1 - 6.7e-50 169.2 0.2 2.1e-25 89.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KXS96017.1 - 7.9e-21 75.1 0.2 2.2e-05 24.5 0.0 4.3 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 KXS96017.1 - 2.7e-20 72.8 54.7 4.5e-11 42.5 17.4 2.6 2 1 0 2 2 2 2 ABC-2 family transporter protein SMC_N PF02463.19 KXS96017.1 - 2.6e-10 40.1 2.3 0.00032 20.2 0.1 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KXS96017.1 - 4.3e-07 29.6 1.9 0.004 16.9 0.5 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KXS96017.1 - 3.7e-05 24.3 4.3 0.026 15.0 0.2 2.8 3 0 0 3 3 2 2 AAA domain RsgA_GTPase PF03193.16 KXS96017.1 - 9.8e-05 22.3 0.3 0.18 11.7 0.3 2.5 2 0 0 2 2 2 2 RsgA GTPase DUF4162 PF13732.6 KXS96017.1 - 0.00014 22.5 0.1 0.0021 18.8 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) AAA_16 PF13191.6 KXS96017.1 - 0.0032 17.9 0.1 0.87 9.9 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain SRP54 PF00448.22 KXS96017.1 - 0.0052 16.4 0.3 1.5 8.4 0.3 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_15 PF13175.6 KXS96017.1 - 0.0059 16.4 0.0 2.7 7.6 0.2 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_27 PF13514.6 KXS96017.1 - 0.0087 15.7 0.1 1.5 8.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 KXS96017.1 - 0.019 15.2 0.2 22 5.4 0.0 4.0 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 KXS96017.1 - 0.023 14.8 1.4 3.6 7.7 0.1 3.6 4 0 0 4 4 4 0 AAA domain G-alpha PF00503.20 KXS96017.1 - 0.026 13.7 0.0 0.11 11.6 0.0 1.9 2 0 0 2 2 2 0 G-protein alpha subunit AAA_22 PF13401.6 KXS96017.1 - 0.026 14.8 0.9 0.84 9.9 0.0 3.0 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KXS96017.1 - 0.088 11.8 0.2 3.9 6.5 0.0 2.6 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_25 PF13481.6 KXS96017.1 - 0.3 10.6 1.3 12 5.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 KXS96017.1 - 1.1 9.5 4.7 4 7.7 0.6 2.9 2 1 1 3 3 3 0 AAA domain AAA_30 PF13604.6 KXS96017.1 - 4.4 7.0 10.8 2.1 8.0 0.2 3.3 3 1 0 4 4 3 0 AAA domain PS_Dcarbxylase PF02666.15 KXS96018.1 - 9.6e-54 182.0 0.0 1.5e-53 181.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Sec5 PF15469.6 KXS96019.1 - 4e-42 144.2 0.0 1.1e-41 142.7 0.0 1.8 1 1 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.11 KXS96019.1 - 4.3e-07 29.9 0.3 3e-06 27.2 0.0 2.7 2 0 0 2 2 2 1 Vps51/Vps67 Carn_acyltransf PF00755.20 KXS96020.1 - 8.9e-202 671.8 0.0 1e-201 671.6 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase UBA2_C PF16195.5 KXS96021.1 - 0.032 14.9 0.1 0.065 13.9 0.1 1.5 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus dCMP_cyt_deam_1 PF00383.23 KXS96022.1 - 1.3e-05 25.0 0.3 5.4e-05 23.0 0.3 2.0 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KXS96022.1 - 1.8e-05 24.5 0.1 0.0014 18.4 0.0 2.3 2 0 0 2 2 2 2 MafB19-like deaminase Peptidase_C69 PF03577.15 KXS96022.1 - 0.033 13.1 0.0 0.053 12.4 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C69 Ldh_1_C PF02866.18 KXS96024.1 - 1.5e-45 155.1 0.1 3.3e-45 154.0 0.1 1.6 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KXS96024.1 - 7.6e-44 149.2 0.1 1.2e-43 148.6 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KXS96024.1 - 0.00051 19.1 0.0 0.00074 18.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.19 KXS96024.1 - 0.011 15.1 0.1 0.084 12.2 0.0 2.3 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain CbiG_N PF11760.8 KXS96024.1 - 0.12 12.4 0.8 0.58 10.2 0.0 2.3 3 0 0 3 3 3 0 Cobalamin synthesis G N-terminal ECH_1 PF00378.20 KXS96028.1 - 5.5e-27 94.7 0.0 6.5e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXS96028.1 - 3e-13 50.0 0.0 3.4e-13 49.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Metallophos PF00149.28 KXS96029.1 - 2.8e-11 44.3 1.6 6.4e-11 43.1 1.6 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF4648 PF15505.6 KXS96032.1 - 0.046 14.6 0.1 0.1 13.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4648) GDI PF00996.18 KXS96033.1 - 8.2e-28 97.1 0.0 2.6e-27 95.4 0.0 1.8 1 1 0 1 1 1 1 GDP dissociation inhibitor DEAD PF00270.29 KXS96034.1 - 1.1e-41 142.6 0.0 2.4e-41 141.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXS96034.1 - 7.5e-31 106.8 0.7 6.4e-29 100.5 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXS96034.1 - 6.4e-05 23.0 0.0 0.00015 21.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KXS96034.1 - 0.012 15.8 0.1 0.052 13.8 0.1 2.1 1 1 0 1 1 1 0 AAA domain Aa_trans PF01490.18 KXS96035.1 - 2e-25 89.4 25.6 2.4e-25 89.1 25.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Peptidase_M3 PF01432.20 KXS96036.1 - 6.5e-117 391.6 0.3 8.7e-117 391.2 0.3 1.2 1 0 0 1 1 1 1 Peptidase family M3 ARID PF01388.21 KXS96037.1 - 4.2e-18 65.8 0.2 1e-17 64.6 0.2 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain zf-C2H2_4 PF13894.6 KXS96037.1 - 0.81 10.7 2.1 2.8 9.0 0.0 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger adh_short PF00106.25 KXS96038.1 - 9.9e-13 48.0 0.0 9.2e-12 44.8 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS96038.1 - 7.7e-08 32.2 0.0 2.7e-07 30.4 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS96038.1 - 4.1e-05 23.6 0.6 9.8e-05 22.3 0.1 1.7 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 KXS96038.1 - 0.0013 18.7 0.6 0.0021 18.0 0.6 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Cadherin_5 PF17892.1 KXS96038.1 - 0.11 12.4 0.2 0.46 10.5 0.2 1.9 2 0 0 2 2 2 0 Cadherin-like domain DinB_2 PF12867.7 KXS96038.1 - 0.13 12.8 0.0 2.9 8.4 0.1 2.2 2 0 0 2 2 2 0 DinB superfamily adh_short_C2 PF13561.6 KXS96039.1 - 6.1e-53 179.8 2.1 7.2e-53 179.5 2.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS96039.1 - 4.7e-36 124.1 0.9 6.3e-36 123.7 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS96039.1 - 4.2e-15 56.1 0.6 5.6e-15 55.7 0.6 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS96039.1 - 2.2e-05 24.0 0.1 5.2e-05 22.8 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXS96039.1 - 0.0042 16.5 0.0 0.0089 15.5 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KXS96039.1 - 0.042 13.0 0.0 0.057 12.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1776 PF08643.10 KXS96039.1 - 0.11 11.9 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Complex1_30kDa PF00329.19 KXS96040.1 - 1.9e-45 154.4 0.0 2.6e-45 154.0 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Ubie_methyltran PF01209.18 KXS96041.1 - 1.2e-73 247.3 0.0 2e-73 246.6 0.0 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 KXS96041.1 - 5e-16 59.2 0.0 9.9e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS96041.1 - 3.7e-13 49.9 0.0 7.9e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS96041.1 - 1.5e-10 41.1 0.0 2.4e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS96041.1 - 4.1e-10 40.3 0.1 8.7e-10 39.2 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXS96041.1 - 1.2e-07 31.7 0.0 3.5e-07 30.2 0.0 1.7 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KXS96041.1 - 0.094 12.3 0.0 0.23 11.0 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain SIS PF01380.22 KXS96042.1 - 5.4e-10 39.2 0.1 3.6e-09 36.5 0.1 2.0 1 1 0 1 1 1 1 SIS domain SIS_2 PF13580.6 KXS96042.1 - 5.5e-07 29.7 0.4 0.00014 21.8 0.3 2.3 1 1 1 2 2 2 2 SIS domain Transglut_core PF01841.19 KXS96042.1 - 0.086 13.3 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 Transglutaminase-like superfamily E1_dh PF00676.20 KXS96043.1 - 5.1e-90 301.5 0.0 6.1e-90 301.2 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KXS96043.1 - 3.9e-05 23.5 0.2 0.00057 19.7 0.2 2.3 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 KXS96043.1 - 0.041 13.1 0.0 0.11 11.6 0.0 1.6 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase EntA_Immun PF08951.10 KXS96043.1 - 0.41 11.1 1.3 1.2 9.5 0.4 2.1 1 1 1 2 2 2 0 Enterocin A Immunity PLAC8 PF04749.17 KXS96044.1 - 2.5e-15 57.3 6.5 4.6e-15 56.4 6.5 1.5 1 0 0 1 1 1 1 PLAC8 family zf-RING_4 PF14570.6 KXS96045.1 - 2.1e-20 72.3 12.2 3.6e-20 71.5 12.2 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 KXS96045.1 - 7.4e-09 35.3 0.0 2.1e-08 33.9 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.6 KXS96045.1 - 2.9e-06 27.0 8.1 6.2e-06 26.0 8.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 KXS96045.1 - 0.00014 21.4 1.8 0.00014 21.4 1.8 2.5 3 0 0 3 3 3 1 Rtf2 RING-finger zf-RING_2 PF13639.6 KXS96045.1 - 0.00049 20.4 10.1 0.00094 19.5 10.1 1.5 1 0 0 1 1 1 1 Ring finger domain Baculo_IE-1 PF05290.11 KXS96045.1 - 0.0016 18.4 3.6 0.0035 17.3 3.6 1.5 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) Prok-RING_4 PF14447.6 KXS96045.1 - 0.0037 17.1 8.7 0.057 13.3 4.6 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-UDP PF14569.6 KXS96045.1 - 0.01 15.9 4.6 0.01 15.9 4.6 1.7 2 0 0 2 2 1 0 Zinc-binding RING-finger FYVE_2 PF02318.16 KXS96045.1 - 0.012 15.8 3.2 0.012 15.8 3.2 2.0 2 0 0 2 2 2 0 FYVE-type zinc finger FYVE PF01363.21 KXS96045.1 - 0.038 14.1 4.4 0.083 13.0 4.4 1.6 1 0 0 1 1 1 0 FYVE zinc finger zf-C3HC4 PF00097.25 KXS96045.1 - 0.052 13.4 10.2 0.11 12.4 10.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXS96045.1 - 0.39 10.7 10.5 0.78 9.8 10.5 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KXS96045.1 - 1.7 8.5 10.8 3.4 7.6 10.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Dfp1_Him1_M PF08630.10 KXS96045.1 - 2.2 8.5 4.5 0.94 9.7 0.9 2.2 2 0 0 2 2 2 0 Dfp1/Him1, central region zf-RING_4 PF14570.6 KXS96046.1 - 2.1e-20 72.3 12.2 3.6e-20 71.5 12.2 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 KXS96046.1 - 7.4e-09 35.3 0.0 2.1e-08 33.9 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.6 KXS96046.1 - 2.9e-06 27.0 8.1 6.2e-06 26.0 8.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 KXS96046.1 - 0.00014 21.4 1.8 0.00014 21.4 1.8 2.5 3 0 0 3 3 3 1 Rtf2 RING-finger zf-RING_2 PF13639.6 KXS96046.1 - 0.00049 20.4 10.1 0.00094 19.5 10.1 1.5 1 0 0 1 1 1 1 Ring finger domain Baculo_IE-1 PF05290.11 KXS96046.1 - 0.0016 18.4 3.6 0.0035 17.3 3.6 1.5 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) Prok-RING_4 PF14447.6 KXS96046.1 - 0.0037 17.1 8.7 0.057 13.3 4.6 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-UDP PF14569.6 KXS96046.1 - 0.01 15.9 4.6 0.01 15.9 4.6 1.7 2 0 0 2 2 1 0 Zinc-binding RING-finger FYVE_2 PF02318.16 KXS96046.1 - 0.012 15.8 3.2 0.012 15.8 3.2 2.0 2 0 0 2 2 2 0 FYVE-type zinc finger FYVE PF01363.21 KXS96046.1 - 0.038 14.1 4.4 0.083 13.0 4.4 1.6 1 0 0 1 1 1 0 FYVE zinc finger zf-C3HC4 PF00097.25 KXS96046.1 - 0.052 13.4 10.2 0.11 12.4 10.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXS96046.1 - 0.39 10.7 10.5 0.78 9.8 10.5 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KXS96046.1 - 1.7 8.5 10.8 3.4 7.6 10.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Dfp1_Him1_M PF08630.10 KXS96046.1 - 2.2 8.5 4.5 0.94 9.7 0.9 2.2 2 0 0 2 2 2 0 Dfp1/Him1, central region zf-RING_4 PF14570.6 KXS96047.1 - 2.1e-20 72.3 12.2 3.6e-20 71.5 12.2 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 KXS96047.1 - 7.4e-09 35.3 0.0 2.1e-08 33.9 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.6 KXS96047.1 - 2.9e-06 27.0 8.1 6.2e-06 26.0 8.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 KXS96047.1 - 0.00014 21.4 1.8 0.00014 21.4 1.8 2.5 3 0 0 3 3 3 1 Rtf2 RING-finger zf-RING_2 PF13639.6 KXS96047.1 - 0.00049 20.4 10.1 0.00094 19.5 10.1 1.5 1 0 0 1 1 1 1 Ring finger domain Baculo_IE-1 PF05290.11 KXS96047.1 - 0.0016 18.4 3.6 0.0035 17.3 3.6 1.5 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) Prok-RING_4 PF14447.6 KXS96047.1 - 0.0037 17.1 8.7 0.057 13.3 4.6 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-UDP PF14569.6 KXS96047.1 - 0.01 15.9 4.6 0.01 15.9 4.6 1.7 2 0 0 2 2 1 0 Zinc-binding RING-finger FYVE_2 PF02318.16 KXS96047.1 - 0.012 15.8 3.2 0.012 15.8 3.2 2.0 2 0 0 2 2 2 0 FYVE-type zinc finger FYVE PF01363.21 KXS96047.1 - 0.038 14.1 4.4 0.083 13.0 4.4 1.6 1 0 0 1 1 1 0 FYVE zinc finger zf-C3HC4 PF00097.25 KXS96047.1 - 0.052 13.4 10.2 0.11 12.4 10.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXS96047.1 - 0.39 10.7 10.5 0.78 9.8 10.5 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KXS96047.1 - 1.7 8.5 10.8 3.4 7.6 10.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Dfp1_Him1_M PF08630.10 KXS96047.1 - 2.2 8.5 4.5 0.94 9.7 0.9 2.2 2 0 0 2 2 2 0 Dfp1/Him1, central region zf-RING_4 PF14570.6 KXS96048.1 - 2.1e-20 72.3 12.2 3.6e-20 71.5 12.2 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 KXS96048.1 - 7.4e-09 35.3 0.0 2.1e-08 33.9 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.6 KXS96048.1 - 2.9e-06 27.0 8.1 6.2e-06 26.0 8.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 KXS96048.1 - 0.00014 21.4 1.8 0.00014 21.4 1.8 2.5 3 0 0 3 3 3 1 Rtf2 RING-finger zf-RING_2 PF13639.6 KXS96048.1 - 0.00049 20.4 10.1 0.00094 19.5 10.1 1.5 1 0 0 1 1 1 1 Ring finger domain Baculo_IE-1 PF05290.11 KXS96048.1 - 0.0016 18.4 3.6 0.0035 17.3 3.6 1.5 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) Prok-RING_4 PF14447.6 KXS96048.1 - 0.0037 17.1 8.7 0.057 13.3 4.6 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-UDP PF14569.6 KXS96048.1 - 0.01 15.9 4.6 0.01 15.9 4.6 1.7 2 0 0 2 2 1 0 Zinc-binding RING-finger FYVE_2 PF02318.16 KXS96048.1 - 0.012 15.8 3.2 0.012 15.8 3.2 2.0 2 0 0 2 2 2 0 FYVE-type zinc finger FYVE PF01363.21 KXS96048.1 - 0.038 14.1 4.4 0.083 13.0 4.4 1.6 1 0 0 1 1 1 0 FYVE zinc finger zf-C3HC4 PF00097.25 KXS96048.1 - 0.052 13.4 10.2 0.11 12.4 10.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXS96048.1 - 0.39 10.7 10.5 0.78 9.8 10.5 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KXS96048.1 - 1.7 8.5 10.8 3.4 7.6 10.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Dfp1_Him1_M PF08630.10 KXS96048.1 - 2.2 8.5 4.5 0.94 9.7 0.9 2.2 2 0 0 2 2 2 0 Dfp1/Him1, central region zf-RING_4 PF14570.6 KXS96049.1 - 2.1e-20 72.3 12.2 3.6e-20 71.5 12.2 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 KXS96049.1 - 7.4e-09 35.3 0.0 2.1e-08 33.9 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.6 KXS96049.1 - 2.9e-06 27.0 8.1 6.2e-06 26.0 8.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 KXS96049.1 - 0.00014 21.4 1.8 0.00014 21.4 1.8 2.5 3 0 0 3 3 3 1 Rtf2 RING-finger zf-RING_2 PF13639.6 KXS96049.1 - 0.00049 20.4 10.1 0.00094 19.5 10.1 1.5 1 0 0 1 1 1 1 Ring finger domain Baculo_IE-1 PF05290.11 KXS96049.1 - 0.0016 18.4 3.6 0.0035 17.3 3.6 1.5 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) Prok-RING_4 PF14447.6 KXS96049.1 - 0.0037 17.1 8.7 0.057 13.3 4.6 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-UDP PF14569.6 KXS96049.1 - 0.01 15.9 4.6 0.01 15.9 4.6 1.7 2 0 0 2 2 1 0 Zinc-binding RING-finger FYVE_2 PF02318.16 KXS96049.1 - 0.012 15.8 3.2 0.012 15.8 3.2 2.0 2 0 0 2 2 2 0 FYVE-type zinc finger FYVE PF01363.21 KXS96049.1 - 0.038 14.1 4.4 0.083 13.0 4.4 1.6 1 0 0 1 1 1 0 FYVE zinc finger zf-C3HC4 PF00097.25 KXS96049.1 - 0.052 13.4 10.2 0.11 12.4 10.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXS96049.1 - 0.39 10.7 10.5 0.78 9.8 10.5 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KXS96049.1 - 1.7 8.5 10.8 3.4 7.6 10.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Dfp1_Him1_M PF08630.10 KXS96049.1 - 2.2 8.5 4.5 0.94 9.7 0.9 2.2 2 0 0 2 2 2 0 Dfp1/Him1, central region HECT PF00632.25 KXS96052.1 - 7e-64 216.2 0.0 1.1e-63 215.6 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 KXS96052.1 - 3.1e-15 56.2 2.0 7.1e-15 55.0 2.0 1.7 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A Redoxin PF08534.10 KXS96053.1 - 2.2e-34 118.3 0.1 2.5e-34 118.1 0.1 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KXS96053.1 - 1.5e-10 41.1 0.0 1.6e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Glyco_hydro_3_C PF01915.22 KXS96054.1 - 2.1e-51 174.8 0.0 4.1e-51 173.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXS96054.1 - 3.1e-33 115.5 0.0 5e-33 114.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXS96054.1 - 2.9e-13 49.7 0.0 6.4e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF5464 PF17552.2 KXS96054.1 - 0.051 13.8 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5464) Aldedh PF00171.22 KXS96055.1 - 3.7e-114 381.8 0.0 4.5e-114 381.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family CorA PF01544.18 KXS96056.1 - 2.4e-09 36.9 0.1 3.9e-09 36.2 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein ApoL PF05461.11 KXS96056.1 - 0.14 11.5 1.8 0.29 10.4 1.8 1.6 1 1 0 1 1 1 0 Apolipoprotein L DDE_Tnp_ISL3 PF01610.17 KXS96056.1 - 0.15 11.8 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Transposase NAT PF04768.13 KXS96057.1 - 1.7e-48 164.5 0.0 3.8e-48 163.3 0.0 1.6 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Semialdhyde_dh PF01118.24 KXS96057.1 - 7.2e-34 116.8 0.0 4.3e-33 114.3 0.0 2.2 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.28 KXS96057.1 - 1.8e-31 109.6 0.6 1.7e-30 106.4 0.1 2.4 2 0 0 2 2 2 1 Amino acid kinase family DapB_N PF01113.20 KXS96057.1 - 0.009 16.1 0.0 0.025 14.7 0.0 1.8 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Sacchrp_dh_NADP PF03435.18 KXS96057.1 - 0.012 15.9 0.0 0.038 14.3 0.0 1.9 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain GFO_IDH_MocA PF01408.22 KXS96057.1 - 0.092 13.6 0.0 0.29 12.0 0.0 1.9 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DUF1977 PF09320.11 KXS96063.1 - 7.8e-31 106.5 0.0 1.3e-30 105.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 KXS96063.1 - 7.3e-22 77.3 0.1 1.5e-21 76.3 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain Abhydrolase_3 PF07859.13 KXS96065.1 - 4.7e-49 167.1 0.0 5.9e-49 166.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXS96065.1 - 1.5e-09 37.3 0.1 2.2e-08 33.4 0.1 2.1 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 KXS96065.1 - 8.3e-05 23.3 0.1 0.00013 22.7 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KXS96065.1 - 0.0048 16.4 0.0 0.22 11.0 0.1 2.4 2 1 0 2 2 2 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 KXS96065.1 - 0.22 10.4 0.0 0.33 9.8 0.0 1.4 1 1 0 1 1 1 0 Steryl acetyl hydrolase ABC_membrane PF00664.23 KXS96066.1 - 5.3e-89 298.5 33.1 7.8e-45 153.6 15.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXS96066.1 - 4.3e-69 231.3 0.1 1.6e-33 116.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KXS96066.1 - 2.2e-12 46.9 6.2 0.00033 20.1 0.5 4.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KXS96066.1 - 2.3e-07 30.9 0.0 0.0039 17.1 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KXS96066.1 - 2.6e-07 31.0 1.7 0.011 16.0 0.1 3.8 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KXS96066.1 - 8.2e-07 28.8 0.1 0.014 15.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KXS96066.1 - 3.6e-06 26.6 1.9 0.0082 15.9 0.8 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.29 KXS96066.1 - 1.1e-05 25.9 2.8 0.0053 17.2 0.2 4.2 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXS96066.1 - 1.5e-05 25.4 6.3 0.069 13.5 0.2 3.5 2 2 1 3 3 3 2 AAA ATPase domain ABC_ATPase PF09818.9 KXS96066.1 - 2.6e-05 23.2 2.6 0.066 12.0 0.2 3.1 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_30 PF13604.6 KXS96066.1 - 5.7e-05 22.9 2.4 0.63 9.7 0.1 3.7 3 1 0 3 3 3 2 AAA domain AAA_5 PF07728.14 KXS96066.1 - 9.8e-05 22.4 0.1 1.1 9.3 0.0 3.3 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 KXS96066.1 - 0.00027 20.8 0.0 0.76 9.4 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KXS96066.1 - 0.0007 19.5 0.0 9.2 6.0 0.0 3.6 3 1 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KXS96066.1 - 0.002 18.6 0.5 1.4 9.4 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 KXS96066.1 - 0.0047 16.5 0.1 4.2 6.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region ATP_bind_1 PF03029.17 KXS96066.1 - 0.0057 16.5 0.3 3.9 7.2 0.0 2.8 3 0 0 3 3 2 1 Conserved hypothetical ATP binding protein SbcCD_C PF13558.6 KXS96066.1 - 0.0059 16.8 3.0 3.8 7.8 0.3 4.1 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 KXS96066.1 - 0.0068 16.6 0.0 1.5 9.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KXS96066.1 - 0.015 15.7 0.1 3.5 8.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.6 KXS96066.1 - 0.015 15.8 0.0 7.2 7.2 0.0 3.0 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 KXS96066.1 - 0.015 14.9 0.0 5.3 6.6 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Rad17 PF03215.15 KXS96066.1 - 0.019 14.9 0.0 0.19 11.6 0.0 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_28 PF13521.6 KXS96066.1 - 0.061 13.6 0.1 2.7 8.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 KXS96066.1 - 0.079 12.1 0.0 2.9 7.0 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit APS_kinase PF01583.20 KXS96066.1 - 0.13 12.1 0.2 3.5 7.5 0.1 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase Zeta_toxin PF06414.12 KXS96066.1 - 0.16 11.2 2.5 6 6.1 0.0 3.5 4 0 0 4 4 4 0 Zeta toxin AAA_24 PF13479.6 KXS96066.1 - 0.17 11.6 0.3 24 4.6 0.1 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KXS96066.1 - 0.17 11.8 0.3 15 5.5 0.1 2.5 2 0 0 2 2 2 0 NACHT domain DUF87 PF01935.17 KXS96066.1 - 0.47 10.5 1.7 1.9 8.5 0.2 2.6 3 0 0 3 3 2 0 Helicase HerA, central domain Ydc2-catalyt PF09159.10 KXS96067.1 - 3.1e-56 191.2 0.0 6.5e-56 190.1 0.0 1.5 1 1 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.13 KXS96067.1 - 0.00052 20.1 0.1 0.36 10.9 0.0 3.1 2 1 0 2 2 2 2 Poxvirus A22 protein Peptidase_S10 PF00450.22 KXS96068.1 - 1.2e-115 387.3 0.0 1.5e-115 387.0 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Hydrolase_4 PF12146.8 KXS96068.1 - 0.082 12.2 0.0 11 5.2 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF533 PF04391.12 KXS96069.1 - 0.0094 15.5 0.1 0.025 14.2 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF533) TrbC PF04956.13 KXS96069.1 - 0.039 14.2 1.8 0.051 13.8 0.5 1.9 2 0 0 2 2 2 0 TrbC/VIRB2 family Nucleo_P87 PF07267.11 KXS96069.1 - 0.35 9.7 11.9 0.53 9.1 11.9 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Yae1_N PF09811.9 KXS96071.1 - 2.9e-11 42.9 2.7 6.1e-11 41.8 2.7 1.6 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Hormone_5 PF00184.17 KXS96072.1 - 0.004 17.9 0.1 0.0052 17.6 0.1 1.1 1 0 0 1 1 1 1 Neurohypophysial hormones, C-terminal Domain Pkinase PF00069.25 KXS96074.1 - 2.8e-27 95.7 0.0 3.6e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS96074.1 - 1.5e-14 54.0 0.0 2e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXS96074.1 - 3e-07 29.6 0.7 4.1e-07 29.1 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Peptidase_M44 PF03410.13 KXS96074.1 - 0.22 10.1 0.0 0.31 9.6 0.0 1.1 1 0 0 1 1 1 0 Metallopeptidase from vaccinia pox Sec23_trunk PF04811.15 KXS96076.1 - 2.4e-76 256.5 0.0 3.8e-76 255.9 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Aa_trans PF01490.18 KXS96076.1 - 3.1e-62 210.6 24.4 4.3e-62 210.1 24.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Sec23_BS PF08033.12 KXS96076.1 - 3.2e-29 101.5 0.1 7.3e-29 100.4 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 KXS96076.1 - 2.1e-25 88.5 0.3 7.5e-25 86.7 0.1 2.1 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 KXS96076.1 - 6.8e-15 54.8 7.8 1.5e-14 53.7 7.8 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KXS96076.1 - 6.8e-11 41.9 0.0 1.6e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 KXS96076.1 - 0.17 11.3 0.9 0.45 9.9 0.4 1.9 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Mif2_N PF15624.6 KXS96076.1 - 0.46 11.2 4.0 0.74 10.5 3.3 1.8 2 0 0 2 2 2 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Caskin-Pro-rich PF16907.5 KXS96076.1 - 2.7 8.6 4.8 10 6.7 4.8 1.9 1 0 0 1 1 1 0 Proline rich region of Caskin proteins Aim19 PF10315.9 KXS96077.1 - 0.00054 20.2 0.1 0.0008 19.7 0.1 1.4 1 1 0 1 1 1 1 Altered inheritance of mitochondria protein 19 DUF3292 PF11696.8 KXS96077.1 - 0.21 9.9 0.1 0.26 9.6 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) PRELI PF04707.14 KXS96078.1 - 3.3e-42 144.0 0.1 3.8e-42 143.8 0.1 1.0 1 0 0 1 1 1 1 PRELI-like family Rad52_Rad22 PF04098.15 KXS96079.1 - 4e-60 202.2 0.0 6.1e-60 201.6 0.0 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Fungal_trans PF04082.18 KXS96080.1 - 3.8e-11 42.5 0.1 1.7e-10 40.4 0.1 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Sugarporin_N PF11471.8 KXS96080.1 - 0.046 13.7 0.8 0.15 12.1 0.8 1.9 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension ABC_tran_CTD PF16326.5 KXS96080.1 - 0.17 12.2 0.5 9.8 6.5 0.0 3.0 3 0 0 3 3 3 0 ABC transporter C-terminal domain DUF4611 PF15387.6 KXS96081.1 - 0.038 14.2 1.9 0.093 13.0 1.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Herpes_DNAp_acc PF04929.12 KXS96081.1 - 0.16 10.9 5.1 0.21 10.5 5.1 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor F-box-like PF12937.7 KXS96083.1 - 0.00019 21.2 0.1 0.0006 19.7 0.2 1.8 2 0 0 2 2 2 1 F-box-like DUF5556 PF17711.1 KXS96083.1 - 0.027 14.4 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5556) DUF2201_N PF13203.6 KXS96094.1 - 0.05 13.2 4.2 0.063 12.9 4.2 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF4407 PF14362.6 KXS96094.1 - 0.25 10.7 6.8 0.3 10.4 6.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4051 PF13260.6 KXS96094.1 - 0.38 10.5 0.1 0.38 10.5 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) CDC45 PF02724.14 KXS96094.1 - 0.48 8.6 6.4 0.54 8.5 6.4 1.1 1 0 0 1 1 1 0 CDC45-like protein ALMT PF11744.8 KXS96094.1 - 0.5 9.1 3.3 0.64 8.8 3.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter CRA PF06589.11 KXS96094.1 - 5.5 7.1 6.3 9.4 6.4 6.3 1.3 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) PTR2 PF00854.21 KXS96095.1 - 2.1e-87 293.6 8.1 3.8e-87 292.7 8.1 1.4 1 0 0 1 1 1 1 POT family PXA PF02194.15 KXS96095.1 - 4.9e-26 91.8 0.2 1.2e-25 90.6 0.0 1.8 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 KXS96095.1 - 8.7e-20 71.4 0.0 3.6e-19 69.4 0.0 2.2 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 KXS96095.1 - 2e-07 31.0 0.0 2.5e-06 27.5 0.0 2.4 2 0 0 2 2 2 1 PX domain DUF1772 PF08592.11 KXS96095.1 - 0.29 11.4 0.0 0.29 11.4 0.0 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF1772) Peptidase_C48 PF02902.19 KXS96096.1 - 3.1e-05 23.9 0.0 6.3e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain tRNA-synt_1b PF00579.25 KXS96097.1 - 8.7e-56 189.4 0.0 1.1e-55 189.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) BRCT_2 PF16589.5 KXS96098.1 - 5e-14 52.5 0.0 9.6e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 KXS96098.1 - 0.00042 20.2 0.1 0.00078 19.3 0.1 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 KXS96098.1 - 0.0048 17.2 0.0 0.0079 16.6 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KXS96098.1 - 0.055 13.8 0.0 0.099 12.9 0.0 1.5 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain EB1 PF03271.17 KXS96100.1 - 1.9e-06 28.0 2.4 4.1e-06 26.9 2.4 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif KRE1 PF17056.5 KXS96101.1 - 0.018 14.8 0.0 7.1 6.4 0.0 2.5 2 0 0 2 2 2 0 Killer toxin-resistance protein 1 DUF2937 PF11157.8 KXS96101.1 - 1.3 8.8 5.2 12 5.5 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) HET PF06985.11 KXS96102.1 - 8.2e-31 107.3 1.0 1.5e-30 106.4 1.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 KXS96104.1 - 3.1e-22 79.0 41.6 3.1e-22 79.0 41.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 KXS96104.1 - 1.8 6.8 10.0 0.14 10.5 2.5 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector zf-MYND PF01753.18 KXS96111.1 - 3.7e-07 30.1 19.5 7.2e-07 29.2 19.5 1.5 1 0 0 1 1 1 1 MYND finger Rhodanese_C PF12368.8 KXS96111.1 - 0.016 15.6 5.9 0.016 15.6 5.9 1.6 2 0 0 2 2 2 0 Rhodanase C-terminal Ig_Tie2_1 PF10430.9 KXS96111.1 - 0.059 13.8 0.6 0.086 13.3 0.6 1.3 1 0 0 1 1 1 0 Tie-2 Ig-like domain 1 zf-C6H2 PF15801.5 KXS96111.1 - 0.15 12.3 9.5 0.32 11.3 9.5 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding DUF1100 PF06500.11 KXS96119.1 - 2.8e-12 46.2 0.0 4.1e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_1 PF00561.20 KXS96119.1 - 1e-07 31.8 0.2 1.9e-06 27.7 0.1 2.5 2 1 1 3 3 3 1 alpha/beta hydrolase fold Esterase PF00756.20 KXS96119.1 - 2.3e-07 30.7 0.0 2.2e-06 27.5 0.0 2.5 1 1 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 KXS96119.1 - 1.9e-06 27.3 0.0 3.1e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 MPLKIP PF15502.6 KXS96119.1 - 3.6e-05 23.9 0.0 0.00012 22.2 0.0 1.9 1 0 0 1 1 1 1 M-phase-specific PLK1-interacting protein Abhydrolase_6 PF12697.7 KXS96119.1 - 0.0041 17.8 0.2 0.0077 16.9 0.1 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KXS96119.1 - 0.0061 16.4 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Sugar_tr PF00083.24 KXS96121.1 - 6e-79 266.0 24.6 7e-79 265.8 24.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS96121.1 - 3e-21 75.7 39.6 1.2e-20 73.8 32.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS96122.1 - 6e-79 266.0 24.6 7e-79 265.8 24.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS96122.1 - 3e-21 75.7 39.6 1.2e-20 73.8 32.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG7_N PF16420.5 KXS96123.1 - 1.7e-111 372.7 0.1 2.2e-111 372.3 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 KXS96123.1 - 4.8e-39 134.2 0.0 7.4e-39 133.6 0.0 1.2 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 KXS96123.1 - 0.05 13.7 0.0 0.16 12.0 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Methyltransf_31 PF13847.6 KXS96124.1 - 3.3e-25 88.7 0.0 4.4e-25 88.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS96124.1 - 2.5e-22 79.3 0.0 4.1e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS96124.1 - 2.3e-20 73.1 0.0 4.2e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXS96124.1 - 1.6e-15 57.1 0.0 2.2e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KXS96124.1 - 2.5e-14 53.5 0.0 3.4e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS96124.1 - 2.6e-13 50.6 0.0 3.9e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXS96124.1 - 1.2e-06 28.2 0.0 2e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.12 KXS96124.1 - 7.8e-06 25.2 0.0 1.1e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_16 PF10294.9 KXS96124.1 - 0.00021 21.1 0.0 0.0005 19.8 0.0 1.7 2 0 0 2 2 2 1 Lysine methyltransferase Methyltransf_2 PF00891.18 KXS96124.1 - 0.00043 19.7 0.0 0.00058 19.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain PCMT PF01135.19 KXS96124.1 - 0.00059 19.6 0.0 0.00088 19.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 KXS96124.1 - 0.0016 18.4 0.0 0.0026 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KXS96124.1 - 0.0043 16.5 0.0 0.0063 16.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 KXS96124.1 - 0.005 16.4 0.0 0.0099 15.5 0.0 1.4 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW FtsJ PF01728.19 KXS96124.1 - 0.016 15.3 0.0 0.044 13.9 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase DUF938 PF06080.12 KXS96124.1 - 0.056 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltr_RsmB-F PF01189.17 KXS96124.1 - 0.058 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F RrnaAD PF00398.20 KXS96124.1 - 0.074 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase AMMECR1 PF01871.17 KXS96124.1 - 0.14 11.7 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 AMMECR1 Methyltransf_4 PF02390.17 KXS96124.1 - 0.17 11.4 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Glyco_hydro_76 PF03663.14 KXS96126.1 - 3.2e-26 92.7 16.3 1.5e-20 74.0 2.6 2.4 2 1 0 2 2 2 2 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KXS96126.1 - 0.002 17.3 0.8 0.0072 15.4 0.3 2.0 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 CDI PF02234.19 KXS96127.1 - 0.048 13.8 0.5 0.082 13.1 0.5 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor Glyco_hydro_76 PF03663.14 KXS96128.1 - 3.2e-26 92.7 16.3 1.5e-20 74.0 2.6 2.4 2 1 0 2 2 2 2 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KXS96128.1 - 0.002 17.3 0.8 0.0072 15.4 0.3 2.0 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 AD PF09793.9 KXS96129.1 - 1.9e-22 79.2 1.8 1.9e-22 79.2 1.8 1.6 2 0 0 2 2 2 1 Anticodon-binding domain LSM14 PF12701.7 KXS96129.1 - 0.057 13.5 0.0 0.096 12.8 0.0 1.4 1 0 0 1 1 1 0 Scd6-like Sm domain DUF4132 PF13569.6 KXS96132.1 - 0.0085 15.9 0.8 0.013 15.3 0.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4132) Rad4 PF03835.15 KXS96133.1 - 5.9e-07 29.3 0.0 1.3e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 KXS96133.1 - 1.1e-06 29.0 0.2 2.6e-06 27.8 0.2 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily YdjO PF14169.6 KXS96133.1 - 0.32 10.7 5.7 2.2 8.1 1.6 2.4 1 1 1 2 2 2 0 Cold-inducible protein YdjO TSP_1 PF00090.19 KXS96133.1 - 4 7.7 8.6 3.5 7.9 1.8 2.9 2 0 0 2 2 2 0 Thrombospondin type 1 domain DUF4633 PF15464.6 KXS96133.1 - 9.3 6.4 11.6 0.12 12.5 1.3 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4633) SUR7 PF06687.12 KXS96137.1 - 1.9e-36 125.7 13.4 2.4e-36 125.4 13.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family Dodecin PF07311.12 KXS96137.1 - 0.27 11.5 1.2 0.62 10.4 1.2 1.6 1 0 0 1 1 1 0 Dodecin DUF2418 PF10332.9 KXS96137.1 - 2.4 8.7 4.7 13 6.3 3.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2418) Na_H_Exchanger PF00999.21 KXS96138.1 - 1.5e-61 208.3 46.2 2e-61 207.9 46.2 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Pkinase PF00069.25 KXS96139.1 - 9.3e-75 251.4 0.0 1.1e-74 251.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS96139.1 - 1.1e-35 123.2 0.0 1.5e-35 122.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KXS96139.1 - 0.00097 18.2 0.0 0.023 13.6 0.0 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KXS96139.1 - 0.015 14.6 0.0 0.033 13.5 0.0 1.7 1 1 0 1 1 1 0 Kinase-like Kdo PF06293.14 KXS96139.1 - 0.02 14.2 0.0 0.054 12.9 0.0 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXS96139.1 - 0.057 13.3 1.1 0.075 12.9 0.1 1.7 2 1 0 2 2 2 0 Phosphotransferase enzyme family DUF1451 PF07295.11 KXS96139.1 - 0.079 13.0 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Zinc-ribbon containing domain MFS_1 PF07690.16 KXS96140.1 - 5.6e-38 130.8 36.4 7.7e-31 107.3 17.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KXS96140.1 - 0.0015 16.9 0.1 0.0023 16.3 0.1 1.4 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family SirB PF04247.12 KXS96140.1 - 0.1 12.7 3.0 0.071 13.2 0.5 2.1 2 0 0 2 2 2 0 Invasion gene expression up-regulator, SirB MFS_1 PF07690.16 KXS96141.1 - 5.6e-38 130.8 36.4 7.7e-31 107.3 17.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KXS96141.1 - 0.0015 16.9 0.1 0.0023 16.3 0.1 1.4 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family SirB PF04247.12 KXS96141.1 - 0.1 12.7 3.0 0.071 13.2 0.5 2.1 2 0 0 2 2 2 0 Invasion gene expression up-regulator, SirB MFS_1 PF07690.16 KXS96143.1 - 5.6e-38 130.8 36.4 7.7e-31 107.3 17.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KXS96143.1 - 0.0015 16.9 0.1 0.0023 16.3 0.1 1.4 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family SirB PF04247.12 KXS96143.1 - 0.1 12.7 3.0 0.071 13.2 0.5 2.1 2 0 0 2 2 2 0 Invasion gene expression up-regulator, SirB MFS_1 PF07690.16 KXS96144.1 - 5.6e-38 130.8 36.4 7.7e-31 107.3 17.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KXS96144.1 - 0.0015 16.9 0.1 0.0023 16.3 0.1 1.4 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family SirB PF04247.12 KXS96144.1 - 0.1 12.7 3.0 0.071 13.2 0.5 2.1 2 0 0 2 2 2 0 Invasion gene expression up-regulator, SirB LtrA PF06772.11 KXS96146.1 - 2.6e-47 161.8 26.3 3.3e-47 161.4 26.3 1.1 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) baeRF_family3 PF18845.1 KXS96146.1 - 0.061 13.6 0.9 0.08 13.2 0.3 1.5 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 3 GAS PF13851.6 KXS96146.1 - 0.071 12.4 0.2 0.11 11.8 0.2 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding NAM-associated PF14303.6 KXS96147.1 - 0.84 10.3 9.3 5.1 7.8 3.4 3.0 1 1 1 2 2 2 0 No apical meristem-associated C-terminal domain Nop25 PF09805.9 KXS96147.1 - 1.5 9.3 6.7 0.38 11.2 1.3 2.2 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Hydrolase_4 PF12146.8 KXS96148.1 - 1.4e-12 47.5 0.0 3.4e-10 39.6 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXS96148.1 - 1.8e-11 45.0 0.3 1.8e-11 45.0 0.3 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXS96148.1 - 1.3e-10 41.4 0.0 1.4e-09 38.0 0.1 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold FSH1 PF03959.13 KXS96148.1 - 0.0071 16.0 0.0 0.13 11.9 0.0 2.2 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.7 KXS96148.1 - 0.029 14.1 0.0 2.1 8.1 0.1 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family BAAT_C PF08840.11 KXS96148.1 - 0.053 13.4 0.0 1.2 9.0 0.1 2.1 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal TFIIS_M PF07500.14 KXS96149.1 - 6.6e-18 65.2 0.4 6.6e-18 65.2 0.4 1.7 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.13 KXS96149.1 - 9.7e-15 54.8 0.0 1.7e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 SPOC domain PHD PF00628.29 KXS96149.1 - 6.4e-10 38.8 8.0 1.1e-09 38.0 8.0 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KXS96149.1 - 0.036 13.6 2.7 0.061 12.9 2.7 1.3 1 0 0 1 1 1 0 PHD-finger tRNA-synt_2 PF00152.20 KXS96150.1 - 1.5e-73 247.6 0.3 2.1e-73 247.2 0.3 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KXS96150.1 - 3.1e-08 33.5 0.1 1.3e-07 31.4 0.0 2.1 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KXS96150.1 - 6.4e-06 25.8 0.1 0.021 14.3 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) DUF3336 PF11815.8 KXS96151.1 - 2.1e-27 95.5 0.7 3.3e-27 94.9 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KXS96151.1 - 9.4e-23 81.5 0.1 3.4e-22 79.6 0.0 2.0 2 0 0 2 2 2 1 Patatin-like phospholipase EnY2 PF10163.9 KXS96152.1 - 7.6e-07 29.4 0.0 1.2e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Transcription factor e(y)2 Lebercilin PF15619.6 KXS96153.1 - 8e-05 22.4 8.5 8e-05 22.4 8.5 7.8 3 1 4 7 7 7 2 Ciliary protein causing Leber congenital amaurosis disease DUF1515 PF07439.11 KXS96153.1 - 0.021 14.8 0.8 0.021 14.8 0.8 6.8 4 2 5 9 9 9 0 Protein of unknown function (DUF1515) NHase_beta PF02211.15 KXS96153.1 - 0.031 14.3 0.4 0.031 14.3 0.4 2.5 2 1 0 2 2 2 0 Nitrile hydratase beta subunit Lip_prot_lig_C PF10437.9 KXS96153.1 - 7.3 6.7 8.6 33 4.6 0.1 4.6 4 0 0 4 4 4 0 Bacterial lipoate protein ligase C-terminus WD40 PF00400.32 KXS96154.1 - 5.7e-12 46.0 17.9 0.7 10.9 0.2 10.1 10 0 0 10 10 10 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS96154.1 - 3.7e-10 40.0 0.2 2.1 8.7 0.0 6.5 3 2 2 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXS96154.1 - 0.0011 18.0 0.0 0.11 11.4 0.0 3.2 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KXS96154.1 - 0.2 11.6 1.7 3.4 7.7 0.0 3.5 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Cwf_Cwc_15 PF04889.12 KXS96154.1 - 0.55 9.9 3.0 0.99 9.1 3.0 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Cyclin_N PF00134.23 KXS96155.1 - 1.6e-36 124.9 0.5 3.7e-36 123.7 0.5 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KXS96155.1 - 5.4e-12 45.8 0.8 2e-11 44.0 0.8 2.0 1 1 0 1 1 1 1 Cyclin, C-terminal domain AflR PF08493.10 KXS96156.1 - 3.4e-26 92.4 12.0 3.4e-26 92.4 12.0 1.6 2 0 0 2 2 2 1 Aflatoxin regulatory protein Zn_clus PF00172.18 KXS96156.1 - 4.5e-09 36.3 8.3 1e-08 35.1 8.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WEMBL PF05701.11 KXS96156.1 - 0.023 13.4 0.1 0.031 13.0 0.1 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light PPP4R2 PF09184.11 KXS96157.1 - 3 7.4 11.2 4 6.9 11.2 1.1 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 KXS96157.1 - 4.5 5.4 14.9 5.7 5.0 14.9 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 KXS96157.1 - 7.4 5.8 11.6 9.3 5.5 11.6 1.1 1 0 0 1 1 1 0 BUD22 Mpp10 PF04006.12 KXS96157.1 - 8 4.8 10.2 10 4.4 10.2 1.1 1 0 0 1 1 1 0 Mpp10 protein Sec66 PF09802.9 KXS96158.1 - 4.9e-79 264.1 1.9 7e-79 263.6 1.9 1.2 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 CstA PF02554.14 KXS96158.1 - 0.012 14.5 0.0 0.017 14.1 0.0 1.1 1 0 0 1 1 1 0 Carbon starvation protein CstA DUF3848 PF12959.7 KXS96158.1 - 0.06 13.4 0.1 0.17 12.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3848) MFS_1 PF07690.16 KXS96159.1 - 4.9e-37 127.7 49.8 4.9e-37 127.7 49.8 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily V_ATPase_I PF01496.19 KXS96159.1 - 0.13 10.1 0.1 0.19 9.6 0.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NDUF_B12 PF08122.12 KXS96159.1 - 0.92 9.6 2.6 36 4.5 0.0 4.0 3 1 1 4 4 4 0 NADH-ubiquinone oxidoreductase B12 subunit family FAM176 PF14851.6 KXS96159.1 - 1.4 8.6 3.4 2.5 7.7 1.1 2.4 2 0 0 2 2 2 0 FAM176 family adh_short PF00106.25 KXS96161.1 - 2.1e-51 174.2 0.1 2.9e-51 173.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS96161.1 - 1.5e-34 119.6 0.1 2e-34 119.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS96161.1 - 2.1e-15 57.1 0.1 2.8e-15 56.7 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS96161.1 - 0.00013 21.5 0.0 0.00076 19.0 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KXS96161.1 - 0.043 13.1 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Aldo_ket_red PF00248.21 KXS96162.1 - 1.6e-60 204.8 0.0 2.1e-60 204.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Lipoprotein_Ltp PF07553.11 KXS96162.1 - 0.023 14.9 0.0 0.045 14.0 0.0 1.5 1 0 0 1 1 1 0 Host cell surface-exposed lipoprotein HOOK PF05622.12 KXS96162.1 - 0.092 10.9 0.3 0.14 10.3 0.3 1.1 1 0 0 1 1 1 0 HOOK protein adh_short_C2 PF13561.6 KXS96163.1 - 9.2e-52 175.9 0.0 1.3e-51 175.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS96163.1 - 1.5e-39 135.5 0.0 2e-39 135.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS96163.1 - 3e-15 56.6 0.1 4e-15 56.2 0.1 1.1 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 KXS96163.1 - 0.00031 19.8 0.1 0.00075 18.6 0.1 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KXS96163.1 - 0.00098 18.7 0.0 0.0022 17.5 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 KXS96163.1 - 0.0036 16.7 0.0 0.014 14.7 0.0 1.8 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 KXS96163.1 - 0.0039 16.7 0.0 0.0061 16.0 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KXS96163.1 - 0.0055 15.9 0.0 0.0075 15.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 KXS96163.1 - 0.032 14.1 0.0 0.085 12.7 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KXS96163.1 - 0.033 14.4 0.0 6 7.0 0.0 2.2 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase EcKinase PF02958.20 KXS96164.1 - 2.5e-13 50.0 0.0 3.9e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 KXS96164.1 - 6.5e-07 29.5 0.0 1.8e-06 28.1 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXS96164.1 - 0.0088 15.7 0.0 0.058 13.0 0.0 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase EthD PF07110.11 KXS96165.1 - 2.4e-18 67.1 0.3 4.9e-18 66.1 0.2 1.5 2 0 0 2 2 2 1 EthD domain MmlI PF09448.10 KXS96165.1 - 0.00064 20.2 0.1 0.001 19.5 0.1 1.3 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase Imm9 PF15587.6 KXS96165.1 - 0.12 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 9 DUF1772 PF08592.11 KXS96166.1 - 5.5e-33 114.2 3.7 7.2e-33 113.8 3.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) AA_kinase PF00696.28 KXS96167.1 - 3.3e-40 138.2 0.9 4.5e-40 137.8 0.9 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 KXS96167.1 - 2.1e-15 56.4 0.2 6.3e-15 54.9 0.2 1.9 1 0 0 1 1 1 1 PUA domain RalF_SCD PF18248.1 KXS96168.1 - 0.1 12.6 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 RalF C-terminal Sec-7 capping domain NPL4 PF05021.15 KXS96169.1 - 1.1e-129 432.2 0.0 1.6e-129 431.7 0.0 1.2 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 KXS96169.1 - 2.2e-71 238.7 1.3 3.7e-71 238.0 1.3 1.4 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 KXS96169.1 - 0.056 13.9 0.0 0.29 11.7 0.0 2.1 1 1 0 1 1 1 0 Nuclear pore localisation protein NPL4 Fungal_trans PF04082.18 KXS96170.1 - 2.9e-16 59.3 4.0 5e-16 58.5 2.9 1.9 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS96170.1 - 8e-06 25.9 10.0 1.3e-05 25.2 10.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2894 PF11445.8 KXS96170.1 - 0.047 14.2 0.8 0.14 12.6 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) FAT PF02259.23 KXS96171.1 - 0.023 13.9 0.6 0.03 13.5 0.6 1.1 1 0 0 1 1 1 0 FAT domain CARD_2 PF16739.5 KXS96171.1 - 0.035 14.1 1.3 0.082 12.9 0.7 1.8 1 1 1 2 2 2 0 Caspase recruitment domain BHD_1 PF10403.9 KXS96171.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 1 TMPIT PF07851.13 KXS96171.1 - 0.19 10.9 0.7 0.23 10.7 0.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein DIT1_PvcA PF05141.12 KXS96171.1 - 0.94 8.9 3.6 5.1 6.5 3.6 2.0 1 1 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein F-box-like PF12937.7 KXS96172.1 - 0.00039 20.3 0.0 0.0014 18.5 0.0 2.0 1 1 0 1 1 1 1 F-box-like Lactamase_B PF00753.27 KXS96173.1 - 3.7e-14 53.2 5.8 3.5e-13 50.0 5.8 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXS96173.1 - 1.7e-05 24.4 0.7 3.4e-05 23.5 0.7 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain BLACT_WH PF17778.1 KXS96173.1 - 0.015 15.2 0.2 0.25 11.4 0.0 2.8 3 0 0 3 3 3 0 Beta-lactamase associated winged helix domain Glyco_hydro_35 PF01301.19 KXS96174.1 - 9.8e-84 281.7 0.5 1.5e-83 281.1 0.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 KXS96174.1 - 1.4e-50 170.6 0.4 1.1e-27 96.9 0.0 2.6 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 KXS96174.1 - 1.5e-48 165.0 4.3 3.6e-48 163.8 4.3 1.7 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 KXS96174.1 - 1.1e-21 76.1 0.6 3.5e-21 74.6 0.0 2.1 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Glyco_hydro_42 PF02449.15 KXS96174.1 - 2.8e-05 23.6 0.0 0.00055 19.4 0.1 2.6 1 1 1 2 2 2 1 Beta-galactosidase zf-RING_2 PF13639.6 KXS96176.1 - 7.5e-13 48.6 5.9 1.2e-12 48.0 5.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KXS96176.1 - 1e-08 34.8 0.3 1.8e-08 34.0 0.3 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KXS96176.1 - 1.6e-08 34.3 2.6 2.6e-08 33.6 2.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXS96176.1 - 2.2e-08 33.8 5.8 3.5e-08 33.1 5.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXS96176.1 - 1.6e-06 28.0 3.1 2.5e-06 27.3 3.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KXS96176.1 - 4.1e-06 27.0 9.3 2.8e-05 24.3 9.3 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KXS96176.1 - 9.2e-05 22.4 0.9 9.2e-05 22.4 0.9 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KXS96176.1 - 0.00054 20.0 1.7 0.0011 19.0 1.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KXS96176.1 - 0.00056 19.7 1.9 0.00096 19.0 1.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) OAD_gamma PF04277.13 KXS96176.1 - 0.023 15.3 0.1 0.52 11.0 0.0 2.8 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain PHD PF00628.29 KXS96176.1 - 0.03 14.2 5.6 0.056 13.4 5.6 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.6 KXS96176.1 - 0.039 13.8 6.3 0.071 12.9 6.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KXS96176.1 - 0.084 12.7 4.0 0.19 11.6 4.0 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 RINGv PF12906.7 KXS96176.1 - 0.17 12.0 2.6 0.36 11.0 2.6 1.6 1 1 0 1 1 1 0 RING-variant domain Zn_ribbon_17 PF17120.5 KXS96176.1 - 0.19 11.4 3.9 0.36 10.5 3.9 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 KXS96176.1 - 0.26 11.5 3.9 0.54 10.5 3.9 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 KXS96176.1 - 0.45 10.7 3.1 1.3 9.3 3.1 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain Rad50_zn_hook PF04423.14 KXS96176.1 - 3.5 7.5 4.8 3.5 7.5 1.2 2.5 3 0 0 3 3 3 0 Rad50 zinc hook motif Prok-RING_1 PF14446.6 KXS96176.1 - 6.2 6.8 9.2 0.18 11.8 1.8 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 ChaC PF04752.12 KXS96177.1 - 5.4e-53 179.7 0.0 6.8e-53 179.4 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein Unstab_antitox PF09720.10 KXS96177.1 - 0.42 10.7 2.9 1.6 8.9 0.5 2.3 2 0 0 2 2 2 0 Putative addiction module component p450 PF00067.22 KXS96178.1 - 2.1e-30 105.9 0.0 3.6e-30 105.1 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 KXS96179.1 - 1.7e-08 33.8 0.0 3.9e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain HCV_NS4b PF01001.19 KXS96179.1 - 0.0056 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Hepatitis C virus non-structural protein NS4b GDI PF00996.18 KXS96180.1 - 3.6e-193 642.0 0.0 4.2e-193 641.7 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Pyr_redox PF00070.27 KXS96180.1 - 0.094 13.3 0.3 2.6 8.7 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Aldolase_II PF00596.21 KXS96181.1 - 2.5e-45 154.7 0.0 6.5e-45 153.4 0.0 1.7 1 1 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain ketoacyl-synt PF00109.26 KXS96182.1 - 1e-71 241.5 0.0 1.2e-70 238.0 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 KXS96182.1 - 9e-47 159.8 0.2 1.8e-45 155.6 0.0 2.7 2 1 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 KXS96182.1 - 5.4e-44 151.0 0.3 1e-43 150.1 0.3 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXS96182.1 - 1.2e-33 115.6 0.8 3.6e-33 114.1 0.8 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KXS96182.1 - 9.6e-12 45.4 0.0 2.7e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PS-DH PF14765.6 KXS96182.1 - 3.1e-11 43.1 0.0 5.6e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.25 KXS96182.1 - 3.6e-11 43.2 0.4 8.3e-11 42.1 0.4 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 KXS96182.1 - 7.8e-05 22.2 0.0 0.00019 20.9 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.26 KXS96183.1 - 1.4e-53 182.1 0.0 1.1e-45 156.2 0.0 3.4 3 0 0 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 KXS96183.1 - 1e-46 159.6 0.2 1.9e-45 155.5 0.0 2.7 2 1 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 KXS96183.1 - 6.1e-44 150.8 0.3 1.1e-43 150.0 0.3 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXS96183.1 - 1.3e-33 115.5 0.8 3.7e-33 114.0 0.8 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KXS96183.1 - 1e-11 45.3 0.0 2.8e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PS-DH PF14765.6 KXS96183.1 - 3.2e-11 43.0 0.0 5.9e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.25 KXS96183.1 - 3.8e-11 43.2 0.4 8.6e-11 42.0 0.4 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Aldo_ket_red PF00248.21 KXS96184.1 - 8.5e-49 166.3 0.0 9.7e-49 166.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FMO-like PF00743.19 KXS96185.1 - 2.9e-26 92.0 0.2 3.2e-22 78.6 0.1 2.6 2 1 1 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXS96185.1 - 1.1e-23 84.0 0.0 4.4e-22 78.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXS96185.1 - 8.6e-16 58.0 0.0 2.7e-13 49.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXS96185.1 - 1.6e-15 57.1 0.1 1.9e-11 43.8 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KXS96185.1 - 1.1e-08 35.5 0.2 0.0094 16.5 0.1 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KXS96185.1 - 1.1e-07 31.4 0.5 0.014 14.7 0.1 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 KXS96185.1 - 5.1e-07 29.8 0.0 8.3e-05 22.8 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KXS96185.1 - 3.1e-06 26.7 0.2 0.0016 17.8 0.0 2.5 2 0 0 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.6 KXS96185.1 - 3.8e-06 27.0 0.3 1.1 9.2 0.0 3.6 2 1 1 3 3 3 3 FAD-NAD(P)-binding HI0933_like PF03486.14 KXS96185.1 - 2.4e-05 23.2 0.1 0.006 15.3 0.0 2.7 3 0 0 3 3 3 1 HI0933-like protein IlvN PF07991.12 KXS96185.1 - 7.3e-05 22.4 0.0 0.0012 18.4 0.1 2.3 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 KXS96185.1 - 0.00016 21.9 0.1 0.044 14.1 0.0 2.6 2 0 0 2 2 2 1 TrkA-N domain F420_oxidored PF03807.17 KXS96185.1 - 0.00023 21.7 0.0 2.1 9.0 0.0 3.4 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent FAD_binding_2 PF00890.24 KXS96185.1 - 0.00025 20.3 0.0 0.051 12.6 0.0 3.0 3 0 0 3 3 3 1 FAD binding domain ApbA PF02558.16 KXS96185.1 - 0.00051 19.7 0.0 0.41 10.3 0.0 3.0 3 0 0 3 3 3 1 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 KXS96185.1 - 0.00054 19.3 0.1 0.13 11.6 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KXS96185.1 - 0.0012 18.8 0.1 0.14 12.1 0.0 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KXS96185.1 - 0.0032 17.5 0.0 0.52 10.4 0.1 2.7 3 0 0 3 3 2 1 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.12 KXS96185.1 - 0.0034 16.5 0.1 0.14 11.2 0.0 2.7 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_7 PF13241.6 KXS96185.1 - 0.0047 17.4 0.0 0.25 11.8 0.0 2.6 2 0 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.17 KXS96185.1 - 0.0083 15.4 0.1 4.9 6.3 0.0 3.3 4 0 0 4 4 3 1 Thi4 family GIDA PF01134.22 KXS96185.1 - 0.0098 15.0 0.3 5.2 6.0 0.1 3.2 4 0 0 4 4 4 1 Glucose inhibited division protein A NAD_binding_2 PF03446.15 KXS96185.1 - 0.016 15.4 0.2 2.2 8.4 0.1 2.3 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase DAO PF01266.24 KXS96185.1 - 0.016 14.8 3.3 0.59 9.7 0.1 3.1 3 1 0 4 4 3 0 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.23 KXS96185.1 - 0.034 14.1 0.1 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ELFV_dehydrog PF00208.21 KXS96185.1 - 0.038 13.7 0.4 0.065 12.9 0.4 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase SnoaL_2 PF12680.7 KXS96185.1 - 0.083 13.5 0.9 0.27 11.9 0.0 2.3 2 1 1 3 3 1 0 SnoaL-like domain AdoHcyase_NAD PF00670.21 KXS96185.1 - 0.089 12.9 0.2 0.54 10.3 0.1 2.2 3 0 0 3 3 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KXS96185.1 - 0.091 12.3 0.0 0.76 9.3 0.0 2.1 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF498 PF04430.14 KXS96185.1 - 0.14 12.2 0.0 4.3 7.4 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF498/DUF598) NOG1_N PF17835.1 KXS96186.1 - 2.1e-48 164.3 0.0 2.1e-48 164.3 0.0 2.2 3 0 0 3 3 3 1 NOG1 N-terminal helical domain NOGCT PF08155.11 KXS96186.1 - 1e-25 89.4 2.1 1e-25 89.4 2.1 2.5 3 0 0 3 3 3 1 NOGCT (NUC087) domain NOG1 PF06858.14 KXS96186.1 - 1.6e-25 88.6 0.2 3.4e-25 87.6 0.2 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 KXS96186.1 - 8.8e-15 54.8 0.0 1.9e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXS96186.1 - 1.1e-08 34.8 0.1 2.4e-08 33.6 0.1 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KXS96186.1 - 0.00013 21.9 0.1 0.054 13.4 0.2 3.0 2 0 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 KXS96186.1 - 0.001 18.5 0.1 0.0019 17.6 0.1 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Dynamin_N PF00350.23 KXS96186.1 - 0.017 15.2 1.7 4.6 7.3 0.0 3.0 2 1 1 3 3 3 0 Dynamin family AAA_18 PF13238.6 KXS96186.1 - 0.048 14.2 0.1 0.28 11.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Sugar_tr PF00083.24 KXS96187.1 - 8.1e-98 328.2 18.9 9.9e-98 327.9 18.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS96187.1 - 4.5e-26 91.6 20.9 4.5e-26 91.6 20.9 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXS96187.1 - 0.00057 18.4 2.4 0.00076 18.0 0.7 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF4088 PF13317.6 KXS96189.1 - 0.086 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4088) Sec63 PF02889.16 KXS96190.1 - 6.8e-164 543.2 0.5 2.1e-91 305.7 0.0 3.0 3 0 0 3 3 3 2 Sec63 Brl domain DEAD PF00270.29 KXS96190.1 - 6.5e-47 159.6 0.4 4.1e-26 91.8 0.1 3.5 4 0 0 4 4 4 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 KXS96190.1 - 1.2e-30 105.9 0.3 4.3e-30 104.1 0.3 2.0 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 KXS96190.1 - 1e-20 74.5 0.1 4.6e-13 49.5 0.0 2.9 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KXS96190.1 - 1.1e-11 45.0 0.0 2.6e-08 34.2 0.0 3.9 3 2 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KXS96190.1 - 1.5e-06 28.6 0.1 0.01 16.1 0.0 3.1 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 KXS96190.1 - 6.8e-06 25.3 0.0 0.17 10.9 0.0 3.3 3 0 0 3 3 3 2 Type II/IV secretion system protein PhoH PF02562.16 KXS96190.1 - 0.00033 20.2 0.0 0.08 12.4 0.0 2.7 2 0 0 2 2 2 1 PhoH-like protein UvrD-helicase PF00580.21 KXS96190.1 - 0.013 15.0 0.8 2.1 7.8 0.0 3.3 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain AAA_11 PF13086.6 KXS96190.1 - 0.037 13.8 0.3 1.5 8.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 KXS96190.1 - 0.041 14.4 0.2 23 5.4 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 KXS96190.1 - 0.13 12.6 2.1 21 5.4 0.0 3.3 3 0 0 3 3 3 0 AAA domain DUF3328 PF11807.8 KXS96191.1 - 0.023 14.5 1.7 1.5 8.5 0.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3328) Thioredoxin PF00085.20 KXS96192.1 - 0.009 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin DUF4047 PF13256.6 KXS96193.1 - 0.073 13.3 6.5 0.99 9.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) Metal_resist PF13801.6 KXS96193.1 - 0.37 11.0 2.6 1.5 9.0 0.7 2.5 2 1 0 2 2 2 0 Heavy-metal resistance MscS_porin PF12795.7 KXS96194.1 - 0.028 14.0 0.9 0.075 12.6 0.9 1.7 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain BLOC1_2 PF10046.9 KXS96194.1 - 0.04 14.2 0.1 0.094 13.0 0.1 1.5 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 KXS96194.1 - 0.078 13.4 0.6 19 5.8 0.1 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 KXS96194.1 - 0.75 10.2 1.9 2 8.9 0.2 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) SlyX PF04102.12 KXS96194.1 - 9.2 7.0 20.8 0.3 11.7 1.2 4.3 4 0 0 4 4 4 0 SlyX MscS_porin PF12795.7 KXS96195.1 - 0.028 14.0 0.9 0.075 12.6 0.9 1.7 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain BLOC1_2 PF10046.9 KXS96195.1 - 0.04 14.2 0.1 0.094 13.0 0.1 1.5 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 KXS96195.1 - 0.078 13.4 0.6 19 5.8 0.1 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 KXS96195.1 - 0.75 10.2 1.9 2 8.9 0.2 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) SlyX PF04102.12 KXS96195.1 - 9.2 7.0 20.8 0.3 11.7 1.2 4.3 4 0 0 4 4 4 0 SlyX Pcc1 PF09341.10 KXS96196.1 - 2.2e-30 104.6 0.5 4.1e-30 103.7 0.2 1.6 2 0 0 2 2 2 1 Transcription factor Pcc1 Amidase PF01425.21 KXS96197.1 - 2.4e-83 280.6 0.2 3.4e-83 280.1 0.2 1.2 1 0 0 1 1 1 1 Amidase Pcc1 PF09341.10 KXS96198.1 - 2.2e-30 104.6 0.5 4.1e-30 103.7 0.2 1.6 2 0 0 2 2 2 1 Transcription factor Pcc1 AA_permease_2 PF13520.6 KXS96199.1 - 3.4e-59 200.8 43.8 4.3e-59 200.4 43.8 1.1 1 0 0 1 1 1 1 Amino acid permease Sulfate_transp PF00916.20 KXS96199.1 - 0.00056 18.8 1.8 0.0013 17.6 0.3 1.9 2 0 0 2 2 2 1 Sulfate permease family Mito_carr PF00153.27 KXS96200.1 - 6.3e-52 173.5 5.2 8.8e-19 67.2 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Nnf1 PF03980.14 KXS96201.1 - 1.3e-28 99.6 1.2 1.3e-28 99.6 1.2 2.1 1 1 1 2 2 2 1 Nnf1 KxDL PF10241.9 KXS96201.1 - 0.011 16.0 0.2 0.029 14.6 0.2 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein zf-CpG_bind_C PF12269.8 KXS96201.1 - 0.044 13.6 1.0 1.8 8.3 0.9 2.1 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain Syntaxin_2 PF14523.6 KXS96201.1 - 0.11 12.9 0.7 0.25 11.7 0.1 1.9 2 0 0 2 2 2 0 Syntaxin-like protein DUF1664 PF07889.12 KXS96201.1 - 0.11 12.5 0.4 0.26 11.4 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF641 PF04859.12 KXS96201.1 - 0.13 12.6 0.9 0.23 11.8 0.9 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Spc7 PF08317.11 KXS96201.1 - 0.57 9.0 5.5 0.2 10.5 3.0 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein Med21 PF11221.8 KXS96201.1 - 7.3 6.8 9.8 2.1 8.6 4.1 2.8 1 1 1 2 2 2 0 Subunit 21 of Mediator complex DUF3591 PF12157.8 KXS96203.1 - 1.1e-170 568.1 0.1 1.5e-170 567.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC PF00098.23 KXS96203.1 - 0.0049 16.9 0.7 0.0095 16.0 0.7 1.5 1 0 0 1 1 1 1 Zinc knuckle Anti-TRAP PF15777.5 KXS96203.1 - 0.16 11.9 0.7 0.45 10.5 0.7 1.7 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein Elf1 PF05129.13 KXS96203.1 - 0.2 11.7 1.6 0.65 10.1 1.6 1.8 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-CCHC_6 PF15288.6 KXS96203.1 - 0.26 11.2 2.3 0.7 9.8 2.3 1.8 1 0 0 1 1 1 0 Zinc knuckle UQ_con PF00179.26 KXS96204.1 - 1.4e-42 144.7 0.2 6.1e-29 100.5 0.0 2.9 3 0 0 3 3 3 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXS96204.1 - 1.3e-06 28.2 0.0 8.9e-05 22.2 0.0 2.4 2 0 0 2 2 2 2 Prokaryotic E2 family B UEV PF05743.13 KXS96204.1 - 0.02 14.8 0.0 0.51 10.2 0.0 2.3 2 0 0 2 2 2 0 UEV domain RNase_T PF00929.24 KXS96205.1 - 6e-08 33.4 0.0 1.3e-07 32.3 0.0 1.6 1 0 0 1 1 1 1 Exonuclease Peptidase_S8 PF00082.22 KXS96207.1 - 2.1e-30 106.0 16.1 3.2e-30 105.4 16.1 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KXS96207.1 - 0.03 15.0 0.0 0.07 13.8 0.0 1.6 1 0 0 1 1 1 0 Peptidase inhibitor I9 DUF2974 PF11187.8 KXS96207.1 - 0.076 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) POB3_N PF17292.2 KXS96208.1 - 4.4e-32 110.4 0.1 1.2e-29 102.5 0.0 3.0 3 0 0 3 3 3 1 POB3-like N-terminal PH domain SSrecog PF03531.14 KXS96208.1 - 3e-28 97.5 2.1 1.8e-27 95.0 0.0 3.1 4 0 0 4 4 4 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 KXS96208.1 - 2.8e-27 94.9 0.1 4.9e-26 91.0 0.0 2.6 3 0 0 3 3 3 1 Histone chaperone Rttp106-like DUF2201_N PF13203.6 KXS96208.1 - 5.3 6.6 7.3 4.7 6.7 0.0 2.2 2 0 0 2 2 2 0 Putative metallopeptidase domain Pkinase PF00069.25 KXS96209.1 - 6.1e-62 209.4 0.0 1.2e-61 208.4 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS96209.1 - 1.1e-32 113.3 0.0 2.8e-32 112.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KXS96209.1 - 9.5e-12 45.1 0.3 6e-10 39.3 0.1 2.7 2 0 0 2 2 2 1 FHA domain Kdo PF06293.14 KXS96209.1 - 0.00025 20.5 0.1 0.00043 19.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXS96209.1 - 0.00028 20.3 0.0 0.0023 17.3 0.0 2.2 1 1 0 1 1 1 1 Kinase-like Yop-YscD_cpl PF16697.5 KXS96209.1 - 0.0036 17.6 0.0 0.0097 16.2 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Pkinase_fungal PF17667.1 KXS96209.1 - 0.017 13.9 0.5 0.043 12.6 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 KXS96209.1 - 0.13 12.1 0.2 1.5 8.7 0.2 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF2312 PF10073.9 KXS96210.1 - 0.12 12.0 0.1 0.49 10.1 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) Pyr_redox_2 PF07992.14 KXS96211.1 - 6.6e-35 120.8 1.4 8.5e-35 120.4 1.4 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXS96211.1 - 1.3e-12 48.1 0.9 2.6e-11 43.9 0.3 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXS96211.1 - 9.7e-06 25.7 2.6 1 9.3 0.0 4.0 4 0 0 4 4 4 3 FAD-NAD(P)-binding K_oxygenase PF13434.6 KXS96211.1 - 4.4e-05 22.8 0.0 9.2e-05 21.7 0.0 1.5 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KXS96211.1 - 0.00061 19.1 0.3 0.00097 18.5 0.3 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXS96211.1 - 0.042 13.1 1.1 5.7 6.1 0.0 2.6 3 0 0 3 3 3 0 Thi4 family Trp_halogenase PF04820.14 KXS96211.1 - 0.1 11.4 0.5 2.4 6.9 0.5 2.2 2 0 0 2 2 2 0 Tryptophan halogenase YfdX PF10938.8 KXS96211.1 - 0.11 12.4 0.4 25 4.8 0.0 3.1 3 0 0 3 3 3 0 YfdX protein DAO PF01266.24 KXS96211.1 - 1.1 8.8 8.9 24 4.4 1.4 3.9 4 0 0 4 4 4 0 FAD dependent oxidoreductase GMC_oxred_C PF05199.13 KXS96212.1 - 1.3e-29 103.6 0.0 2.2e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KXS96212.1 - 9.2e-25 87.6 0.2 1.3e-15 57.6 0.0 3.4 3 1 0 4 4 4 3 GMC oxidoreductase Pyr_redox_2 PF07992.14 KXS96212.1 - 0.0012 18.1 0.0 0.0058 15.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXS96212.1 - 0.0015 18.7 1.6 0.0021 18.3 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXS96212.1 - 0.0034 16.7 0.1 0.86 8.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXS96212.1 - 0.0042 16.2 0.0 0.0061 15.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KXS96212.1 - 0.005 16.0 0.0 0.0085 15.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain PhoPQ_related PF10142.9 KXS96212.1 - 0.076 11.7 0.0 0.15 10.7 0.0 1.4 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein ApbA PF02558.16 KXS96212.1 - 0.087 12.5 0.5 0.16 11.6 0.5 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Sybindin PF04099.12 KXS96213.1 - 9.7e-46 155.2 0.0 1.2e-45 155.0 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 KXS96213.1 - 1.4e-05 25.3 0.0 2.1e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Tyrosinase PF00264.20 KXS96214.1 - 4.6e-44 151.3 0.1 5.8e-44 151.0 0.1 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF3128 PF11326.8 KXS96215.1 - 1.1e-28 99.4 3.9 1.7e-28 98.8 3.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) CHZ PF09649.10 KXS96217.1 - 1.9e-16 59.2 1.9 1.9e-16 59.2 1.9 2.3 2 1 0 2 2 2 1 Histone chaperone domain CHZ Spc42p PF11544.8 KXS96217.1 - 0.14 12.2 0.1 0.32 11.0 0.0 1.6 1 1 1 2 2 2 0 Spindle pole body component Spc42p PPP4R2 PF09184.11 KXS96217.1 - 6.5 6.3 16.6 8.8 5.8 16.6 1.2 1 0 0 1 1 1 0 PPP4R2 BUD22 PF09073.10 KXS96217.1 - 8 5.7 22.2 8.5 5.6 22.2 1.0 1 0 0 1 1 1 0 BUD22 VIR_N PF15912.5 KXS96217.1 - 9.2 5.8 11.1 10 5.7 11.1 1.0 1 0 0 1 1 1 0 Virilizer, N-terminal HSP70 PF00012.20 KXS96218.1 - 1.3e-261 869.1 5.6 1.5e-261 868.9 5.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KXS96218.1 - 9.9e-17 60.7 0.0 1.3e-15 57.1 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KXS96218.1 - 0.0028 17.4 0.0 0.0085 15.8 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 KXS96218.1 - 0.0034 17.8 1.2 6.6 7.2 0.0 3.4 3 1 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.18 KXS96218.1 - 0.014 14.6 0.1 0.03 13.6 0.1 1.5 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase MetOD2 PF18548.1 KXS96218.1 - 0.37 10.9 3.5 2.4 8.3 0.1 2.5 2 0 0 2 2 2 0 Metanogen output domain 2 PMBR PF09373.10 KXS96218.1 - 0.37 11.0 1.2 0.76 10.0 0.1 2.2 2 0 0 2 2 2 0 Pseudomurein-binding repeat ABC_membrane PF00664.23 KXS96219.1 - 2.1 7.9 4.4 3 7.4 4.4 1.2 1 0 0 1 1 1 0 ABC transporter transmembrane region peroxidase PF00141.23 KXS96221.1 - 1.8e-25 90.0 0.0 3.4e-25 89.1 0.0 1.4 1 0 0 1 1 1 1 Peroxidase Yip1 PF04893.17 KXS96221.1 - 8.8e-13 48.3 15.0 1.8e-12 47.3 15.0 1.5 1 0 0 1 1 1 1 Yip1 domain GATase_2 PF00310.21 KXS96222.1 - 1.4e-179 597.2 0.0 2e-179 596.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 KXS96222.1 - 5.7e-155 516.0 0.0 9.2e-155 515.3 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 KXS96222.1 - 5.8e-116 386.9 0.0 6.7e-114 380.1 0.0 2.4 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 KXS96222.1 - 3.1e-85 284.6 2.6 5.2e-85 283.8 2.6 1.4 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 KXS96222.1 - 6.5e-23 81.4 0.0 3.5e-22 79.0 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 KXS96222.1 - 2.6e-20 72.3 0.0 5.6e-20 71.2 0.0 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 KXS96222.1 - 4.3e-09 36.5 0.0 1.5e-08 34.8 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KXS96222.1 - 5.3e-07 29.3 0.0 9e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KXS96222.1 - 2.5e-06 28.0 0.2 0.00043 20.8 0.1 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXS96222.1 - 3.9e-06 26.7 0.6 0.0014 18.3 0.3 2.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXS96222.1 - 1.4e-05 24.5 3.8 0.0054 16.0 0.0 3.9 4 1 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXS96222.1 - 3.1e-05 22.9 0.1 3.1e-05 22.9 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 KXS96222.1 - 0.0001 21.5 0.1 0.00062 19.0 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 KXS96222.1 - 0.00024 20.6 0.1 0.00051 19.5 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXS96222.1 - 0.0026 17.1 0.2 0.0084 15.4 0.1 1.9 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 KXS96222.1 - 0.0033 16.7 0.0 0.0071 15.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 KXS96222.1 - 0.0035 17.8 1.0 2 8.9 0.1 3.3 4 0 0 4 4 2 1 Putative NAD(P)-binding FMO-like PF00743.19 KXS96222.1 - 0.015 13.8 0.2 0.24 9.8 0.0 2.3 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like AdoHcyase_NAD PF00670.21 KXS96222.1 - 0.018 15.1 0.1 1.7 8.7 0.1 2.7 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Lycopene_cycl PF05834.12 KXS96222.1 - 0.031 13.3 0.2 0.15 11.0 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.22 KXS96222.1 - 0.047 12.8 0.2 0.28 10.2 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.19 KXS96222.1 - 0.049 13.0 0.1 0.18 11.2 0.0 1.9 2 0 0 2 2 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FMN_dh PF01070.18 KXS96222.1 - 0.054 12.5 0.2 0.37 9.7 0.3 2.1 2 0 0 2 2 2 0 FMN-dependent dehydrogenase NAD_binding_9 PF13454.6 KXS96222.1 - 0.062 13.3 0.1 0.24 11.4 0.1 2.0 1 1 0 1 1 1 0 FAD-NAD(P)-binding ApbA PF02558.16 KXS96222.1 - 0.1 12.2 0.1 0.42 10.2 0.1 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 KXS96222.1 - 0.14 11.4 0.1 9.4 5.5 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_Gly3P_dh_N PF01210.23 KXS96222.1 - 0.15 12.0 0.0 0.36 10.8 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.20 KXS96222.1 - 0.18 11.8 0.0 26 4.9 0.0 2.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Acid_phosphat_B PF03767.14 KXS96222.1 - 0.2 11.2 0.0 0.37 10.3 0.0 1.3 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Ras PF00071.22 KXS96223.1 - 0.00013 21.6 0.0 0.00017 21.2 0.0 1.2 1 0 0 1 1 1 1 Ras family Peptidase_C11 PF03415.14 KXS96223.1 - 0.096 12.1 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Clostripain family CFEM PF05730.11 KXS96224.1 - 1.1e-05 25.5 10.7 1.1e-05 25.5 10.7 2.0 2 0 0 2 2 2 1 CFEM domain TatD_DNase PF01026.21 KXS96225.1 - 6e-32 111.0 0.0 8.6e-32 110.5 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase RNA12 PF10443.9 KXS96226.1 - 4.5e-166 553.0 0.0 5.9e-166 552.6 0.0 1.1 1 0 0 1 1 1 1 RNA12 protein ATPase_2 PF01637.18 KXS96226.1 - 1e-06 28.9 0.2 3.9e-06 27.0 0.0 2.1 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea RRM_1 PF00076.22 KXS96226.1 - 1.2e-05 25.1 0.0 3.1e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_16 PF13191.6 KXS96226.1 - 0.0018 18.7 0.1 0.0057 17.1 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain DUF2487 PF10673.9 KXS96226.1 - 0.0027 17.7 0.0 0.014 15.4 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2487) GTP_EFTU PF00009.27 KXS96227.1 - 1.1e-33 116.4 0.0 1.1e-33 116.4 0.0 3.0 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KXS96227.1 - 5.9e-22 77.8 0.1 1.8e-21 76.2 0.1 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 KXS96227.1 - 6.7e-10 39.2 0.3 6.7e-10 39.2 0.3 3.3 3 0 0 3 3 3 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 KXS96227.1 - 1.4e-08 34.6 0.5 6.3e-08 32.4 0.5 2.2 1 1 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 KXS96227.1 - 1e-05 25.6 0.0 1e-05 25.6 0.0 3.5 4 0 0 4 4 4 1 50S ribosome-binding GTPase Roc PF08477.13 KXS96227.1 - 0.0013 19.0 0.0 0.0042 17.3 0.0 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 KXS96227.1 - 0.0018 18.1 0.1 0.01 15.6 0.0 2.5 2 1 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 KXS96227.1 - 1.3 9.3 3.8 1.1 9.5 0.1 2.8 2 1 0 2 2 2 0 AAA domain ATG16 PF08614.11 KXS96228.1 - 0.0011 19.2 1.9 0.0016 18.7 1.9 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) HALZ PF02183.18 KXS96228.1 - 0.016 15.4 6.9 0.36 11.1 4.7 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper HAUS-augmin3 PF14932.6 KXS96228.1 - 0.017 14.7 0.4 0.021 14.4 0.4 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 UPF0242 PF06785.11 KXS96228.1 - 0.026 14.6 0.0 0.028 14.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Lebercilin PF15619.6 KXS96228.1 - 0.028 14.1 3.4 0.04 13.6 3.4 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease GAS PF13851.6 KXS96228.1 - 0.031 13.6 3.5 0.037 13.4 3.5 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding CALCOCO1 PF07888.11 KXS96228.1 - 0.032 13.1 0.7 0.037 12.9 0.7 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like MPS2 PF17060.5 KXS96228.1 - 0.053 12.8 1.4 0.055 12.7 1.4 1.0 1 0 0 1 1 1 0 Monopolar spindle protein 2 Tropomyosin_1 PF12718.7 KXS96228.1 - 0.069 13.3 1.6 0.098 12.8 1.6 1.1 1 0 0 1 1 1 0 Tropomyosin like FH2 PF02181.23 KXS96228.1 - 0.093 11.8 0.2 0.12 11.5 0.2 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain ADIP PF11559.8 KXS96228.1 - 0.094 12.8 4.5 0.076 13.1 1.7 1.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding JIP_LZII PF16471.5 KXS96228.1 - 0.096 12.9 0.1 7.8 6.8 0.0 2.2 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II Sec2p PF06428.11 KXS96228.1 - 0.14 12.1 0.3 0.21 11.6 0.3 1.3 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Cnn_1N PF07989.11 KXS96228.1 - 0.17 12.1 2.2 0.4 10.9 2.2 1.6 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 ZapB PF06005.12 KXS96228.1 - 1.5 9.3 4.3 42 4.7 4.3 2.1 1 1 0 1 1 1 0 Cell division protein ZapB TM_helix PF05552.12 KXS96232.1 - 1.4 8.9 6.5 0.6 10.1 0.1 2.7 2 0 0 2 2 2 0 Conserved TM helix Atg8 PF02991.16 KXS96234.1 - 2.9e-51 172.0 0.2 3.4e-51 171.8 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KXS96234.1 - 3.2e-06 27.5 0.0 3.8e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Mcl1_mid PF12341.8 KXS96236.1 - 1.1e-102 343.4 0.0 1.5e-101 339.7 0.0 2.3 2 1 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region ANAPC4_WD40 PF12894.7 KXS96236.1 - 2.8e-15 56.4 0.0 2.4e-05 24.6 0.0 5.8 3 1 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXS96236.1 - 5.4e-14 52.4 5.9 0.018 15.9 0.3 6.5 8 0 0 8 8 8 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KXS96236.1 - 3.2e-05 23.1 0.9 0.0039 16.2 0.1 3.9 2 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DNA_pol_alpha_N PF12254.8 KXS96236.1 - 0.018 15.1 0.2 0.045 13.8 0.2 1.7 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal RAB3GAP2_N PF14655.6 KXS96236.1 - 0.069 12.4 0.1 4.4 6.5 0.0 2.5 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PQQ_3 PF13570.6 KXS96236.1 - 5.6 7.6 7.2 9.7 6.8 0.1 3.9 4 0 0 4 4 4 0 PQQ-like domain Ank_3 PF13606.6 KXS96241.1 - 6.9e-16 56.8 3.2 0.00034 20.8 0.0 7.3 8 0 0 8 8 8 3 Ankyrin repeat Ank_2 PF12796.7 KXS96241.1 - 3.1e-15 56.5 0.1 7.8e-05 23.2 0.0 3.4 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXS96241.1 - 6.7e-10 39.0 1.7 5.2e-06 26.6 0.1 3.9 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXS96241.1 - 2.9e-09 37.3 0.8 3.1e-05 24.4 0.0 4.6 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank PF00023.30 KXS96241.1 - 1.1e-08 35.1 8.8 0.00029 21.1 0.1 6.1 5 2 0 5 5 5 2 Ankyrin repeat Glyco_hydro_75 PF07335.11 KXS96242.1 - 3.6e-59 199.7 0.1 4.8e-59 199.3 0.1 1.2 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 MFS_1 PF07690.16 KXS96243.1 - 1.3e-32 113.1 19.0 1.3e-32 113.1 19.0 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KXS96243.1 - 1e-05 24.6 0.2 2.1e-05 23.6 0.2 1.6 1 0 0 1 1 1 1 MFS_1 like family HsbA PF12296.8 KXS96244.1 - 4.4e-22 78.8 12.8 7.4e-22 78.0 12.8 1.4 1 0 0 1 1 1 1 Hydrophobic surface binding protein A HpcH_HpaI PF03328.14 KXS96248.1 - 3.4e-25 88.5 0.7 5.4e-25 87.8 0.7 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Methyltransf_23 PF13489.6 KXS96249.1 - 8e-10 38.8 0.0 1.2e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS96249.1 - 3.6e-06 26.9 0.0 1.2e-05 25.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS96249.1 - 2.5e-05 24.9 0.0 6.5e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS96249.1 - 0.00062 20.5 0.0 0.0013 19.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS96249.1 - 0.003 18.2 0.0 0.0097 16.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain TPR_12 PF13424.6 KXS96250.1 - 8.6e-09 35.6 24.8 0.018 15.3 0.0 9.2 8 1 1 9 9 9 2 Tetratricopeptide repeat AAA_16 PF13191.6 KXS96250.1 - 1.2e-08 35.5 0.1 9.8e-08 32.6 0.1 2.6 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KXS96250.1 - 4.2e-07 30.0 0.2 1.9e-06 27.9 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 KXS96250.1 - 1.1e-05 25.8 0.0 1.1e-05 25.8 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA PF00004.29 KXS96250.1 - 0.00044 20.7 0.1 0.0035 17.8 0.0 2.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KXS96250.1 - 0.0016 19.0 0.1 0.01 16.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain TPR_6 PF13174.6 KXS96250.1 - 0.0022 18.5 8.5 7.2 7.5 0.0 7.6 7 0 0 7 7 7 1 Tetratricopeptide repeat AAA_33 PF13671.6 KXS96250.1 - 0.0045 17.2 0.0 0.023 14.8 0.0 2.3 1 0 0 1 1 1 1 AAA domain TPR_16 PF13432.6 KXS96250.1 - 0.0086 16.7 4.2 12 6.6 0.0 5.2 6 0 0 6 6 3 0 Tetratricopeptide repeat AAA_28 PF13521.6 KXS96250.1 - 0.012 15.8 0.4 0.15 12.3 0.0 3.1 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.14 KXS96250.1 - 0.016 15.2 0.0 0.053 13.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TPR_7 PF13176.6 KXS96250.1 - 0.016 15.2 17.8 0.17 12.0 0.1 8.2 10 0 0 10 10 9 0 Tetratricopeptide repeat SRP54 PF00448.22 KXS96250.1 - 0.017 14.8 0.0 0.046 13.4 0.0 1.7 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ResIII PF04851.15 KXS96250.1 - 0.021 14.8 0.1 0.34 10.9 0.0 2.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit TsaE PF02367.17 KXS96250.1 - 0.032 14.2 0.5 0.55 10.2 0.0 2.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KXS96250.1 - 0.033 14.6 0.0 0.19 12.2 0.0 2.4 1 0 0 1 1 1 0 RNA helicase TPR_19 PF14559.6 KXS96250.1 - 0.055 14.0 10.4 14 6.3 0.0 6.7 9 0 0 9 9 7 0 Tetratricopeptide repeat AAA_14 PF13173.6 KXS96250.1 - 0.086 12.9 1.1 0.96 9.5 0.0 3.3 3 0 0 3 3 2 0 AAA domain TPR_10 PF13374.6 KXS96250.1 - 0.09 12.7 12.6 14 5.8 0.0 6.7 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXS96250.1 - 2.4 9.2 15.6 2.6 9.1 0.1 7.4 8 1 1 9 9 5 0 Tetratricopeptide repeat LPMO_10 PF03067.15 KXS96251.1 - 4e-11 43.9 1.6 5.4e-11 43.5 1.6 1.2 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Methyltransf_2 PF00891.18 KXS96252.1 - 2e-21 76.2 0.0 3.2e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain ECH_1 PF00378.20 KXS96253.1 - 3.2e-35 121.7 0.0 3.9e-35 121.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXS96253.1 - 6e-15 55.6 0.0 7.2e-15 55.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Dus PF01207.17 KXS96255.1 - 1.2e-61 208.6 0.0 2.1e-61 207.7 0.0 1.4 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 KXS96255.1 - 0.0094 15.4 0.1 0.015 14.8 0.1 1.2 1 0 0 1 1 1 1 Histidine biosynthesis protein PEP_mutase PF13714.6 KXS96255.1 - 0.012 15.1 0.6 0.027 13.9 0.6 1.5 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase AP_endonuc_2 PF01261.24 KXS96255.1 - 0.059 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Dus PF01207.17 KXS96256.1 - 1.2e-61 208.6 0.0 2.1e-61 207.7 0.0 1.4 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 KXS96256.1 - 0.0094 15.4 0.1 0.015 14.8 0.1 1.2 1 0 0 1 1 1 1 Histidine biosynthesis protein PEP_mutase PF13714.6 KXS96256.1 - 0.012 15.1 0.6 0.027 13.9 0.6 1.5 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase AP_endonuc_2 PF01261.24 KXS96256.1 - 0.059 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Paf1 PF03985.13 KXS96258.1 - 7.5e-67 226.2 0.0 1.1e-66 225.6 0.0 1.2 1 0 0 1 1 1 1 Paf1 GCIP PF13324.6 KXS96259.1 - 0.11 12.0 1.6 0.21 11.1 1.6 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Afi1 PF07792.12 KXS96259.1 - 8.3 6.9 11.8 8.2 6.9 2.4 2.5 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DAO PF01266.24 KXS96261.1 - 1.8e-45 156.1 0.5 2.1e-45 155.9 0.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXS96261.1 - 3.6e-05 23.9 0.2 0.00013 22.1 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXS96261.1 - 4.4e-05 22.8 0.0 0.0096 15.2 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXS96261.1 - 0.005 17.4 0.0 0.037 14.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KXS96261.1 - 0.014 15.1 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF3203 PF11462.8 KXS96261.1 - 0.019 15.1 0.0 0.052 13.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3203) NAD_binding_9 PF13454.6 KXS96261.1 - 0.056 13.4 0.1 0.33 10.9 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding DUF3500 PF12006.8 KXS96263.1 - 1e-107 360.1 0.0 1.3e-107 359.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) PAF-AH_p_II PF03403.13 KXS96264.1 - 6.3e-39 133.6 0.0 1e-38 132.9 0.0 1.2 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KXS96264.1 - 0.00025 20.0 0.0 0.00091 18.2 0.0 1.7 1 1 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KXS96264.1 - 0.0065 15.5 0.0 0.033 13.2 0.0 1.9 2 0 0 2 2 2 1 Chlorophyllase Abhydrolase_3 PF07859.13 KXS96264.1 - 0.013 15.4 0.0 0.19 11.5 0.0 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXS96264.1 - 0.014 14.6 0.3 0.84 8.8 0.0 2.9 4 0 0 4 4 4 0 Serine aminopeptidase, S33 DUF2062 PF09835.9 KXS96264.1 - 0.042 13.7 0.0 0.089 12.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) Esterase PF00756.20 KXS96264.1 - 0.052 13.2 0.0 4.5 6.8 0.0 2.4 2 0 0 2 2 2 0 Putative esterase Abhydrolase_6 PF12697.7 KXS96264.1 - 0.097 13.3 1.7 0.19 12.3 0.0 2.3 1 1 1 2 2 2 0 Alpha/beta hydrolase family Sugar_tr PF00083.24 KXS96271.1 - 2.6e-107 359.5 18.4 3.2e-107 359.2 18.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS96271.1 - 2.3e-29 102.4 33.0 8.9e-29 100.5 27.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily SLC3A2_N PF16028.5 KXS96271.1 - 0.18 11.4 1.5 0.46 10.1 0.1 2.5 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus Spt20 PF12090.8 KXS96272.1 - 2.3e-33 115.7 0.0 2.3e-33 115.7 0.0 8.1 2 1 2 5 5 5 1 Spt20 family Kelch_4 PF13418.6 KXS96273.1 - 9.5e-32 108.8 9.8 1.6e-06 28.0 1.0 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 KXS96273.1 - 1.1e-30 105.3 9.8 1.6e-07 31.4 0.2 5.7 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_6 PF13964.6 KXS96273.1 - 1.4e-27 95.0 7.6 5.1e-08 32.9 1.8 6.5 4 2 2 6 6 6 5 Kelch motif Kelch_5 PF13854.6 KXS96273.1 - 1.4e-26 92.0 7.4 2.5e-05 24.1 0.2 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.25 KXS96273.1 - 1.7e-24 85.1 3.0 2.3e-06 27.1 0.4 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 KXS96273.1 - 4.7e-17 61.2 4.1 0.0022 17.9 0.5 6.5 6 0 0 6 6 6 4 Kelch motif ADIP PF11559.8 KXS96273.1 - 0.00052 20.1 9.2 0.00052 20.1 9.2 7.4 5 3 2 8 8 8 3 Afadin- and alpha -actinin-Binding Strep_SA_rep PF06696.11 KXS96273.1 - 1.2 9.2 6.6 11 6.2 0.2 4.3 4 0 0 4 4 4 0 Streptococcal surface antigen repeat CotJB PF12652.7 KXS96273.1 - 1.4 9.1 3.4 7.5 6.9 0.3 3.5 2 1 0 3 3 3 0 CotJB protein PAP1 PF08601.10 KXS96274.1 - 1.6e-07 31.4 8.3 2.8e-07 30.6 0.0 2.1 1 1 1 2 2 2 1 Transcription factor PAP1 bZIP_1 PF00170.21 KXS96274.1 - 3.9e-07 30.1 11.3 6.6e-07 29.3 11.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor SHE3 PF17078.5 KXS96274.1 - 0.0078 16.0 3.6 0.011 15.5 3.6 1.2 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 bZIP_Maf PF03131.17 KXS96274.1 - 0.0089 16.5 9.9 0.014 15.9 9.9 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 KXS96274.1 - 0.078 13.1 11.3 0.17 12.0 10.3 2.1 1 1 1 2 2 2 0 Basic region leucine zipper LemA PF04011.12 KXS96274.1 - 0.22 11.4 4.0 0.33 10.8 4.0 1.2 1 0 0 1 1 1 0 LemA family Glutaredoxin2_C PF04399.13 KXS96274.1 - 0.23 11.3 0.9 0.39 10.6 0.9 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain GvpL_GvpF PF06386.11 KXS96274.1 - 1.8 8.5 5.4 2.6 7.9 5.4 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Methyltrn_RNA_3 PF02598.17 KXS96275.1 - 1.2e-72 244.8 0.0 1.4e-72 244.6 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase Methyltrn_RNA_3 PF02598.17 KXS96276.1 - 2.4e-110 368.6 0.0 2.7e-110 368.4 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase SpoU_methylase PF00588.19 KXS96276.1 - 0.021 15.0 0.0 2.1 8.5 0.0 2.3 2 0 0 2 2 2 0 SpoU rRNA Methylase family GFO_IDH_MocA PF01408.22 KXS96277.1 - 5.4e-14 53.0 0.0 1.1e-13 52.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KXS96277.1 - 0.17 12.6 0.0 0.4 11.4 0.0 1.6 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Het-C PF07217.11 KXS96277.1 - 0.19 10.2 0.0 0.32 9.5 0.0 1.2 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C GFO_IDH_MocA PF01408.22 KXS96278.1 - 5.4e-14 53.0 0.0 1.1e-13 52.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KXS96278.1 - 0.17 12.6 0.0 0.4 11.4 0.0 1.6 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Het-C PF07217.11 KXS96278.1 - 0.19 10.2 0.0 0.32 9.5 0.0 1.2 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C GFO_IDH_MocA PF01408.22 KXS96279.1 - 5.4e-14 53.0 0.0 1.1e-13 52.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KXS96279.1 - 0.17 12.6 0.0 0.4 11.4 0.0 1.6 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Het-C PF07217.11 KXS96279.1 - 0.19 10.2 0.0 0.32 9.5 0.0 1.2 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C ATP-synt_J PF04911.12 KXS96280.1 - 3.7e-28 96.9 1.6 4.3e-28 96.6 1.6 1.0 1 0 0 1 1 1 1 ATP synthase j chain Peroxidase_2 PF01328.17 KXS96281.1 - 4.3e-34 118.7 0.0 6.7e-34 118.1 0.0 1.3 1 0 0 1 1 1 1 Peroxidase, family 2 Gpr1_Fun34_YaaH PF01184.19 KXS96282.1 - 2e-35 122.3 26.9 2.6e-35 121.9 26.9 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF1003 PF06210.11 KXS96282.1 - 0.31 11.1 3.1 7.8 6.7 1.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) WD40 PF00400.32 KXS96283.1 - 2.8e-21 75.4 21.1 0.00062 20.5 0.2 7.4 7 0 0 7 7 7 4 WD domain, G-beta repeat PQQ_3 PF13570.6 KXS96283.1 - 0.00042 20.7 0.4 0.52 10.9 0.0 3.3 3 0 0 3 3 3 2 PQQ-like domain Cytochrom_D1 PF02239.16 KXS96283.1 - 0.00099 17.7 0.5 0.042 12.4 0.0 3.0 4 0 0 4 4 4 1 Cytochrome D1 heme domain ANAPC4_WD40 PF12894.7 KXS96283.1 - 0.022 15.0 0.0 5.5 7.4 0.0 3.8 4 1 1 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KXS96283.1 - 0.042 13.8 0.2 0.27 11.2 0.0 2.5 2 1 0 2 2 2 0 WD40-like Beta Propeller Repeat SDA1 PF05285.12 KXS96283.1 - 4.9 6.5 10.2 7.9 5.8 10.2 1.3 1 0 0 1 1 1 0 SDA1 F-box-like PF12937.7 KXS96284.1 - 6.6e-07 29.1 1.8 1.5e-06 27.9 1.8 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS96284.1 - 0.0037 17.1 0.6 0.012 15.5 0.6 1.9 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KXS96284.1 - 0.046 13.6 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 F-box DUF5610 PF18433.1 KXS96284.1 - 0.2 12.2 0.0 0.54 10.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5610) TauD PF02668.16 KXS96285.1 - 8.8e-42 143.7 0.0 1.1e-41 143.4 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family PAP2_3 PF14378.6 KXS96287.1 - 8.3e-22 77.8 21.8 5.3e-21 75.2 18.8 3.0 2 1 1 3 3 3 1 PAP2 superfamily Sugar_tr PF00083.24 KXS96288.1 - 1.9e-96 323.7 22.0 2.3e-96 323.4 22.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS96288.1 - 1e-19 70.7 35.5 2e-17 63.2 13.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2663 PF10864.8 KXS96288.1 - 0.16 12.3 1.0 1.7 9.0 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2663) DUF3433 PF11915.8 KXS96290.1 - 6.4e-31 106.7 17.0 7.6e-25 87.2 4.0 3.7 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) Ribonuclease_3 PF00636.26 KXS96296.1 - 2e-19 70.1 0.0 5.3e-19 68.8 0.0 1.8 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KXS96296.1 - 2.1e-15 57.0 0.1 7.6e-15 55.2 0.0 1.8 2 0 0 2 2 2 1 Ribonuclease-III-like ECH_1 PF00378.20 KXS96297.1 - 2.1e-35 122.2 0.0 3.1e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXS96297.1 - 1.5e-20 74.0 0.5 2.1e-19 70.2 0.1 1.9 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase MMM1 PF10296.9 KXS96298.1 - 1.9e-134 447.9 0.0 4.6e-134 446.7 0.0 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial morphology protein 1 Zn_clus PF00172.18 KXS96299.1 - 3.1e-07 30.4 9.7 3.1e-07 30.4 9.7 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXS96299.1 - 1e-05 24.7 0.0 3.6e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Glyco_transf_15 PF01793.16 KXS96300.1 - 1.1e-113 379.8 11.9 1.4e-113 379.5 11.9 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase ArgJ PF01960.18 KXS96301.1 - 2.9e-142 473.9 0.0 6.1e-142 472.8 0.0 1.5 1 1 0 1 1 1 1 ArgJ family Smoothelin PF12510.8 KXS96301.1 - 0.082 13.0 0.7 0.16 12.1 0.7 1.4 1 0 0 1 1 1 0 Smoothelin cytoskeleton protein Glyco_hydro_115 PF15979.5 KXS96302.1 - 4.9e-133 443.8 0.1 6.7e-133 443.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 KXS96302.1 - 2.9e-44 150.9 0.0 5.9e-44 149.9 0.0 1.6 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain Glyco_hydro_67N PF03648.14 KXS96302.1 - 0.15 12.4 0.0 0.34 11.2 0.0 1.7 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 N-terminus MRP-S33 PF08293.11 KXS96303.1 - 1.5e-30 105.2 0.2 1.9e-30 104.9 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Methyltransf_32 PF13679.6 KXS96305.1 - 1.4e-23 83.6 0.0 2.7e-23 82.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Creatinase_N_2 PF16189.5 KXS96306.1 - 5.2e-56 189.2 0.0 8.2e-54 182.1 0.0 2.3 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 KXS96306.1 - 8.6e-42 143.2 0.0 1.3e-41 142.6 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 KXS96306.1 - 6.5e-23 80.6 0.3 1.8e-22 79.2 0.3 1.8 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 KXS96306.1 - 1.8e-22 80.4 0.0 1.9e-18 67.4 0.0 2.5 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Med9 PF07544.13 KXS96306.1 - 0.16 12.1 1.6 0.25 11.5 0.2 2.0 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Glu_synthase PF01645.17 KXS96306.1 - 0.23 10.6 0.0 0.64 9.1 0.0 1.6 2 0 0 2 2 2 0 Conserved region in glutamate synthase Bul1_C PF04426.12 KXS96307.1 - 0.0012 18.4 0.1 0.0014 18.1 0.1 1.1 1 0 0 1 1 1 1 Bul1 C terminus Arrestin_C PF02752.22 KXS96307.1 - 0.056 13.9 0.0 0.066 13.7 0.0 1.2 1 0 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain MATalpha_HMGbox PF04769.12 KXS96315.1 - 8.7e-21 74.1 0.2 5.3e-16 58.5 0.1 2.2 1 1 1 2 2 2 2 Mating-type protein MAT alpha 1 HMG-box Anp1 PF03452.14 KXS96316.1 - 3.2e-111 371.0 0.2 7.7e-111 369.7 0.0 1.7 2 0 0 2 2 2 1 Anp1 ATP-synt_I PF03899.15 KXS96316.1 - 0.022 15.1 0.1 0.037 14.4 0.1 1.3 1 0 0 1 1 1 0 ATP synthase I chain Glyco_tranf_2_4 PF13704.6 KXS96316.1 - 0.023 15.2 0.1 0.062 13.8 0.1 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 2 G6PD_bact PF10786.9 KXS96316.1 - 0.079 12.5 3.8 0.036 13.6 1.3 1.7 2 0 0 2 2 2 0 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) Smg8_Smg9 PF10220.9 KXS96316.1 - 1 7.6 8.6 1.4 7.1 8.6 1.1 1 0 0 1 1 1 0 Smg8_Smg9 HSP70 PF00012.20 KXS96316.1 - 2.3 6.3 12.2 3.3 5.8 12.2 1.2 1 0 0 1 1 1 0 Hsp70 protein MATalpha_HMGbox PF04769.12 KXS96317.1 - 8.7e-21 74.1 0.2 5.3e-16 58.5 0.1 2.2 1 1 1 2 2 2 2 Mating-type protein MAT alpha 1 HMG-box Acetyltransf_1 PF00583.25 KXS96318.1 - 1.6e-05 25.1 0.0 2.7e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXS96318.1 - 2.7e-05 24.5 0.0 4.9e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXS96318.1 - 0.00014 22.0 0.2 0.003 17.6 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXS96318.1 - 0.0002 21.3 0.0 0.00034 20.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 KXS96318.1 - 0.00037 20.2 0.1 0.00086 18.9 0.0 1.5 2 0 0 2 2 2 1 GNAT acetyltransferase FR47 PF08445.10 KXS96318.1 - 0.00056 19.8 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KXS96318.1 - 0.019 15.1 0.1 0.055 13.6 0.0 1.9 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Cofilin_ADF PF00241.20 KXS96319.1 - 1.1e-19 70.4 0.0 1.3e-19 70.2 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein PX PF00787.24 KXS96319.1 - 0.056 13.4 0.1 0.065 13.2 0.1 1.3 1 0 0 1 1 1 0 PX domain Pkinase PF00069.25 KXS96320.1 - 1.9e-47 161.9 0.0 5.3e-47 160.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS96320.1 - 3.9e-20 72.2 0.0 8.9e-20 71.0 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KXS96320.1 - 0.051 13.5 1.2 0.071 13.0 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXS96320.1 - 0.068 12.1 0.0 0.068 12.1 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain Acetyltransf_1 PF00583.25 KXS96321.1 - 1e-08 35.4 0.1 1.8e-08 34.6 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXS96321.1 - 0.0061 17.0 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Pho86 PF11124.8 KXS96321.1 - 0.0073 15.8 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Inorganic phosphate transporter Pho86 Acetyltransf_10 PF13673.7 KXS96321.1 - 0.009 15.9 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ATPase_gene1 PF09527.10 KXS96321.1 - 0.026 14.7 2.8 0.059 13.5 2.8 1.6 1 0 0 1 1 1 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Acetyltransf_CG PF14542.6 KXS96321.1 - 0.045 13.9 0.1 0.093 12.9 0.1 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PanZ PF12568.8 KXS96321.1 - 0.05 13.3 0.0 0.12 12.1 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ AA_permease_2 PF13520.6 KXS96323.1 - 2.1e-36 125.7 41.5 2.7e-36 125.3 41.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXS96323.1 - 1e-16 60.7 37.1 1.8e-16 59.8 37.1 1.3 1 1 0 1 1 1 1 Amino acid permease DUF2615 PF11027.8 KXS96323.1 - 0.41 10.8 1.2 2.5 8.3 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) Sec7 PF01369.20 KXS96324.1 - 3.2e-66 222.5 0.7 5.1e-66 221.8 0.7 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KXS96324.1 - 4.2e-19 69.0 0.0 2.3e-18 66.6 0.0 2.3 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 KXS96324.1 - 0.00018 21.2 0.3 0.00018 21.2 0.3 2.4 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7 PF01369.20 KXS96325.1 - 3.2e-66 222.5 0.7 5.1e-66 221.8 0.7 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KXS96325.1 - 4.2e-19 69.0 0.0 2.3e-18 66.6 0.0 2.3 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 KXS96325.1 - 0.00018 21.2 0.3 0.00018 21.2 0.3 2.4 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7 PF01369.20 KXS96326.1 - 3.2e-66 222.5 0.7 5.1e-66 221.8 0.7 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KXS96326.1 - 4.2e-19 69.0 0.0 2.3e-18 66.6 0.0 2.3 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 KXS96326.1 - 0.00018 21.2 0.3 0.00018 21.2 0.3 2.4 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 ABC_tran PF00005.27 KXS96328.1 - 3e-46 157.3 0.0 1e-24 87.6 0.0 2.9 2 0 0 2 2 2 2 ABC transporter CLTH PF10607.9 KXS96328.1 - 2.2e-26 92.5 0.2 4.6e-26 91.5 0.2 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain ABC_membrane PF00664.23 KXS96328.1 - 3.1e-16 59.9 19.5 1e-13 51.6 2.0 2.6 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KXS96328.1 - 6e-11 42.2 2.3 0.0083 15.6 0.0 4.4 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain LisH PF08513.11 KXS96328.1 - 1.7e-08 34.1 0.0 4.7e-08 32.7 0.0 1.8 1 0 0 1 1 1 1 LisH AAA_29 PF13555.6 KXS96328.1 - 4.4e-08 32.7 0.6 0.008 15.9 0.2 3.2 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KXS96328.1 - 3.3e-07 31.0 0.4 0.00034 21.2 0.3 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KXS96328.1 - 1.2e-06 28.9 2.9 0.048 13.9 0.0 3.2 4 0 0 4 4 2 2 AAA domain DUF87 PF01935.17 KXS96328.1 - 1.5e-06 28.5 2.3 0.031 14.4 0.0 3.0 3 0 0 3 3 3 2 Helicase HerA, central domain AAA PF00004.29 KXS96328.1 - 7.2e-06 26.5 0.0 0.013 15.9 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXS96328.1 - 8.9e-06 26.2 0.0 0.1 13.0 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain T2SSE PF00437.20 KXS96328.1 - 1.5e-05 24.2 3.4 0.017 14.2 0.0 2.7 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_33 PF13671.6 KXS96328.1 - 8.8e-05 22.7 0.0 0.25 11.5 0.0 3.0 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.18 KXS96328.1 - 0.00012 21.6 0.3 0.11 11.9 0.1 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family Mg_chelatase PF01078.21 KXS96328.1 - 0.00017 21.1 0.1 0.0082 15.5 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KXS96328.1 - 0.00022 20.8 0.1 0.36 10.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region ATP_bind_1 PF03029.17 KXS96328.1 - 0.00023 21.0 0.0 0.9 9.3 0.0 2.7 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein AAA_15 PF13175.6 KXS96328.1 - 0.00025 20.9 0.2 0.59 9.8 0.1 2.4 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KXS96328.1 - 0.00026 21.0 0.1 0.41 10.5 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase cobW PF02492.19 KXS96328.1 - 0.00037 20.1 0.9 0.12 12.0 0.2 2.7 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.6 KXS96328.1 - 0.00041 20.3 0.2 0.28 10.9 0.0 3.3 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 KXS96328.1 - 0.00055 19.7 0.1 2 8.1 0.0 3.2 3 1 0 3 3 2 2 AAA domain MobB PF03205.14 KXS96328.1 - 0.0011 18.9 0.6 1.1 9.2 0.1 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.14 KXS96328.1 - 0.0018 18.3 0.2 2.1 8.3 0.0 3.4 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) Roc PF08477.13 KXS96328.1 - 0.0022 18.2 0.0 4.7 7.5 0.0 3.6 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 KXS96328.1 - 0.0023 17.2 2.1 0.4 9.8 0.2 3.3 3 1 0 3 3 3 1 NB-ARC domain MMR_HSR1 PF01926.23 KXS96328.1 - 0.0023 18.0 0.0 2.1 8.5 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_11 PF13086.6 KXS96328.1 - 0.0029 17.4 0.4 11 5.7 0.0 3.6 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 KXS96328.1 - 0.0036 16.9 0.1 1.2 8.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KXS96328.1 - 0.0042 17.0 0.2 0.9 9.4 0.0 2.8 2 0 0 2 2 2 1 NACHT domain PduV-EutP PF10662.9 KXS96328.1 - 0.0042 16.8 0.1 0.7 9.6 0.0 3.2 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.6 KXS96328.1 - 0.0047 17.3 0.1 5.3 7.4 0.0 3.1 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KXS96328.1 - 0.0051 16.6 0.3 2.4 7.9 0.0 3.3 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_18 PF13238.6 KXS96328.1 - 0.006 17.1 0.2 8.1 7.0 0.0 3.3 3 0 0 3 3 2 0 AAA domain AAA_24 PF13479.6 KXS96328.1 - 0.0068 16.1 0.2 3.4 7.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KXS96328.1 - 0.007 16.4 0.1 1.1 9.3 0.0 3.6 4 0 0 4 4 3 1 AAA domain RNA12 PF10443.9 KXS96328.1 - 0.0086 14.9 0.2 0.34 9.6 0.1 2.3 2 0 0 2 2 2 1 RNA12 protein Dynamin_N PF00350.23 KXS96328.1 - 0.012 15.7 0.0 0.33 11.0 0.0 2.5 2 0 0 2 2 2 0 Dynamin family Pox_A32 PF04665.12 KXS96328.1 - 0.016 14.7 0.1 4 6.8 0.0 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein ATPase_2 PF01637.18 KXS96328.1 - 0.018 15.0 0.0 3.9 7.3 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KXS96328.1 - 0.026 14.9 0.1 12 6.3 0.0 3.2 3 0 0 3 3 3 0 RNA helicase TsaE PF02367.17 KXS96328.1 - 0.03 14.3 0.1 6.9 6.7 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PRK PF00485.18 KXS96328.1 - 0.031 14.0 0.1 0.58 9.9 0.1 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 KXS96328.1 - 0.15 11.3 0.8 8.1 5.7 0.0 2.8 3 0 0 3 3 2 0 Zeta toxin TrwB_AAD_bind PF10412.9 KXS96328.1 - 0.26 10.2 7.3 0.23 10.3 0.1 2.6 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain NTPase_1 PF03266.15 KXS96328.1 - 0.43 10.5 6.3 7.5 6.4 0.3 3.2 3 1 1 4 4 3 0 NTPase NADHdh-2_N PF12155.8 KXS96328.1 - 1.7 9.0 8.8 2 8.8 2.0 3.3 2 0 0 2 2 2 0 NADH dehydrogenase subunit 2 N-terminal adh_short PF00106.25 KXS96330.1 - 2.4e-24 85.9 0.0 3e-24 85.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS96330.1 - 2.3e-20 73.2 0.1 2.9e-20 72.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS96330.1 - 4.6e-05 23.4 0.0 7.6e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 KXS96330.1 - 0.0044 16.6 0.1 0.012 15.2 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family DUF4431 PF14485.6 KXS96330.1 - 0.13 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4431) Ras PF00071.22 KXS96331.1 - 3.5e-59 199.0 0.2 4.4e-59 198.7 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXS96331.1 - 1.3e-19 70.6 0.0 2e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXS96331.1 - 1.7e-07 30.9 0.0 2.2e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KXS96331.1 - 0.00013 22.0 0.0 0.42 10.5 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KXS96331.1 - 0.00015 21.3 0.1 0.0006 19.4 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 KXS96331.1 - 0.0068 16.4 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 KXS96331.1 - 0.013 15.6 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase FeoB_N PF02421.18 KXS96331.1 - 0.047 13.2 0.0 0.085 12.4 0.0 1.5 1 1 0 1 1 1 0 Ferrous iron transport protein B Zn_clus PF00172.18 KXS96332.1 - 0.00014 21.9 10.1 0.00021 21.3 10.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_10 PF13596.6 KXS96332.1 - 0.042 14.4 0.0 0.16 12.6 0.0 1.8 2 0 0 2 2 2 0 PAS domain PAS_4 PF08448.10 KXS96332.1 - 0.065 13.5 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 PAS fold MoCF_biosynth PF00994.24 KXS96333.1 - 4.7e-33 113.9 0.0 7.1e-33 113.3 0.0 1.2 1 0 0 1 1 1 1 Probable molybdopterin binding domain PRK PF00485.18 KXS96334.1 - 3e-59 200.1 0.0 4.1e-59 199.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 KXS96334.1 - 1.1e-37 129.5 0.0 1.7e-37 128.9 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase CPT PF07931.12 KXS96334.1 - 3.3e-05 23.8 0.0 8.5e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 KXS96334.1 - 0.00039 21.0 0.0 0.00069 20.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KXS96334.1 - 0.024 13.9 0.0 0.047 13.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.6 KXS96334.1 - 0.025 15.0 0.0 0.061 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 KXS96334.1 - 0.068 12.4 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Pribosyltran PF00156.27 KXS96334.1 - 0.085 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase domain ABC_tran PF00005.27 KXS96334.1 - 0.11 13.0 0.5 0.31 11.5 0.1 1.9 2 0 0 2 2 2 0 ABC transporter AAA_33 PF13671.6 KXS96334.1 - 0.12 12.5 0.0 0.4 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KXS96334.1 - 0.17 11.6 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain tRNA_int_endo PF01974.17 KXS96335.1 - 6.7e-15 54.9 0.0 2.2e-14 53.3 0.0 1.8 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain IBR PF01485.21 KXS96336.1 - 2e-17 63.2 21.6 8.2e-10 38.8 5.3 4.1 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain SSP160 PF06933.11 KXS96342.1 - 0.066 11.4 3.1 0.078 11.2 3.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Ribosomal_S16 PF00886.19 KXS96343.1 - 1.1e-21 76.7 0.1 2.5e-21 75.5 0.1 1.6 1 1 0 1 1 1 1 Ribosomal protein S16 F-box PF00646.33 KXS96344.1 - 3.9e-08 33.0 0.2 1.2e-07 31.4 0.2 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXS96344.1 - 4.7e-08 32.8 0.9 1.4e-07 31.2 0.2 2.2 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 KXS96344.1 - 0.15 12.0 0.1 0.4 10.6 0.1 1.7 1 0 0 1 1 1 0 F-box DLH PF01738.18 KXS96345.1 - 5.1e-30 104.6 0.0 6e-30 104.4 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF915 PF06028.11 KXS96345.1 - 0.0075 15.6 0.1 0.015 14.7 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Peptidase_S9 PF00326.21 KXS96345.1 - 0.12 11.8 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family BSD PF03909.17 KXS96346.1 - 4.4e-26 90.7 4.3 1e-11 44.7 0.1 3.5 3 0 0 3 3 3 2 BSD domain PH_TFIIH PF08567.11 KXS96346.1 - 1.2e-22 80.0 0.4 3.1e-22 78.7 0.4 1.8 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain AAA_12 PF13087.6 KXS96347.1 - 8.1e-38 130.0 0.0 1.4e-37 129.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KXS96347.1 - 2.9e-24 86.3 0.1 1.4e-23 84.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXS96347.1 - 4.9e-08 33.4 0.0 7.3e-07 29.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXS96347.1 - 1e-06 28.6 0.0 2.6e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KXS96347.1 - 2e-06 27.7 0.0 0.012 15.4 0.0 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 KXS96347.1 - 0.0065 16.5 0.0 0.021 14.8 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KXS96347.1 - 0.0096 15.7 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase PhoH PF02562.16 KXS96347.1 - 0.015 14.7 0.0 0.032 13.7 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein SpoU_sub_bind PF08032.12 KXS96347.1 - 0.039 14.2 0.2 0.14 12.5 0.2 2.0 1 0 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding DUF2075 PF09848.9 KXS96347.1 - 0.051 12.8 0.0 0.4 9.9 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ORF6C PF10552.9 KXS96347.1 - 0.11 12.6 0.1 0.27 11.3 0.1 1.6 1 0 0 1 1 1 0 ORF6C domain AAA_22 PF13401.6 KXS96347.1 - 0.11 12.7 0.0 0.49 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain UvrD-helicase PF00580.21 KXS96347.1 - 0.14 11.7 0.0 0.41 10.1 0.0 1.9 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_16 PF13191.6 KXS96347.1 - 0.16 12.3 0.0 0.45 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain DLIC PF05783.11 KXS96349.1 - 0.00048 19.1 19.3 0.18 10.6 0.0 5.3 4 1 1 5 5 5 4 Dynein light intermediate chain (DLIC) Septin PF00735.18 KXS96350.1 - 2.1e-106 355.3 0.1 3.6e-106 354.6 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KXS96350.1 - 5.9e-06 26.4 0.0 1.4e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KXS96350.1 - 7.8e-05 22.8 2.6 0.43 10.6 0.0 3.2 2 1 1 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 KXS96350.1 - 0.0025 17.7 0.4 0.016 15.2 0.3 2.3 2 1 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 KXS96350.1 - 0.22 12.0 4.4 6.4 7.2 3.8 2.3 2 0 0 2 2 2 0 AAA domain MFS_1 PF07690.16 KXS96351.1 - 3.9e-20 72.1 49.2 1.1e-19 70.7 42.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KXS96351.1 - 0.021 14.2 25.9 0.067 12.5 25.9 2.0 1 1 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB Glyco_hydro_43 PF04616.14 KXS96352.1 - 3.1e-33 115.3 3.3 5.7e-33 114.5 3.3 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KXS96352.1 - 1.3e-24 87.0 0.0 2e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Abhydrolase_6 PF12697.7 KXS96353.1 - 0.00051 20.7 0.5 0.00096 19.8 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 KXS96353.1 - 0.0074 16.2 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_1 PF00561.20 KXS96353.1 - 0.042 13.5 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1751 PF08551.10 KXS96354.1 - 0.013 16.0 1.6 0.013 16.0 1.6 1.9 1 1 1 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 KXS96354.1 - 0.073 13.1 2.7 0.043 13.8 1.0 1.6 2 0 0 2 2 2 0 Rhomboid family DER1 PF04511.15 KXS96354.1 - 0.83 9.6 7.3 1.1 9.1 7.3 1.4 1 1 0 1 1 1 0 Der1-like family BTB PF00651.31 KXS96355.1 - 4.5e-08 33.3 0.0 1e-07 32.1 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KXS96356.1 - 4.5e-08 33.3 0.0 1e-07 32.1 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain Zn_clus PF00172.18 KXS96357.1 - 5.4e-08 32.8 9.1 1e-07 31.9 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BTB PF00651.31 KXS96358.1 - 0.00029 21.0 0.0 0.00059 20.0 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain zinc-ribbons_6 PF07191.12 KXS96358.1 - 0.5 10.4 7.4 1.1 9.3 7.4 1.5 1 0 0 1 1 1 0 zinc-ribbons HEPN_Swt1 PF18731.1 KXS96359.1 - 0.024 15.0 0.4 0.065 13.6 0.4 1.7 1 0 0 1 1 1 0 Swt1-like HEPN ALS2CR8 PF15299.6 KXS96359.1 - 0.046 13.6 3.0 0.95 9.3 3.0 2.1 1 1 0 1 1 1 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 UPF0172 PF03665.13 KXS96359.1 - 0.19 11.8 2.1 0.21 11.6 0.7 1.8 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0172) F-box-like_2 PF13013.6 KXS96360.1 - 0.041 13.8 0.7 0.12 12.3 0.7 1.9 1 1 0 1 1 1 0 F-box-like domain NAD_binding_8 PF13450.6 KXS96361.1 - 0.0079 16.4 0.0 0.021 15.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 KXS96361.1 - 0.018 15.1 0.0 0.56 10.3 0.0 2.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase K_oxygenase PF13434.6 KXS96361.1 - 0.11 11.6 0.0 0.11 11.6 0.0 3.6 5 0 0 5 5 5 0 L-lysine 6-monooxygenase (NADPH-requiring) Scaffolding_pro PF11418.8 KXS96361.1 - 0.25 11.9 2.0 0.91 10.1 2.0 2.0 1 0 0 1 1 1 0 Phi29 scaffolding protein p450 PF00067.22 KXS96362.1 - 2.2e-52 178.4 0.0 2.8e-52 178.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zinc_ribbon_4 PF13717.6 KXS96363.1 - 0.037 13.9 1.2 0.054 13.4 1.2 1.2 1 0 0 1 1 1 0 zinc-ribbon domain Nodulin_late PF07127.11 KXS96363.1 - 0.097 13.0 0.1 0.15 12.4 0.1 1.2 1 0 0 1 1 1 0 Late nodulin protein RNA_pol_Rpb4 PF03874.16 KXS96371.1 - 7.9e-09 35.9 4.6 3e-08 34.0 4.6 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb4 BCAS2 PF05700.11 KXS96372.1 - 2e-55 187.7 1.8 2.2e-55 187.6 1.8 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) DUF4230 PF14014.6 KXS96372.1 - 0.086 13.1 0.1 0.14 12.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4230) GTP1_OBG PF01018.22 KXS96373.1 - 3.5e-40 137.1 0.3 1.3e-30 106.0 1.4 2.2 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 KXS96373.1 - 3.6e-23 81.8 0.0 6.1e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXS96373.1 - 3e-08 33.3 0.0 8e-08 32.0 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B MeaB PF03308.16 KXS96373.1 - 0.0035 16.4 0.4 0.14 11.1 0.0 2.6 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 KXS96373.1 - 0.029 14.9 0.0 0.057 13.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 KXS96373.1 - 0.04 14.5 0.0 0.18 12.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 KXS96373.1 - 0.07 13.2 0.0 5.1 7.1 0.0 2.5 2 0 0 2 2 2 0 Dynamin family AAA_33 PF13671.6 KXS96373.1 - 0.091 12.9 0.3 0.28 11.3 0.3 1.9 1 1 0 1 1 1 0 AAA domain baeRF_family7 PF18849.1 KXS96373.1 - 0.1 12.8 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 7 Arf PF00025.21 KXS96373.1 - 0.12 11.9 0.1 0.31 10.5 0.1 1.7 2 0 0 2 2 2 0 ADP-ribosylation factor family Alk_phosphatase PF00245.20 KXS96374.1 - 5.9e-102 341.7 0.0 7.6e-102 341.4 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 KXS96374.1 - 2.3e-06 27.2 0.0 3.3e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily OmpA PF00691.20 KXS96374.1 - 0.046 14.1 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 OmpA family RskA PF10099.9 KXS96374.1 - 0.051 13.9 0.1 0.14 12.5 0.0 1.7 2 0 0 2 2 2 0 Anti-sigma-K factor rskA GST_N_2 PF13409.6 KXS96375.1 - 6.6e-09 35.9 0.0 1.2e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXS96375.1 - 1.6e-07 31.6 0.0 3.3e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXS96375.1 - 2.2e-06 27.6 0.0 3.8e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXS96375.1 - 0.00093 19.3 0.0 0.002 18.3 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KXS96375.1 - 0.044 14.4 0.0 0.089 13.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KXS96376.1 - 6.6e-09 35.9 0.0 1.2e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXS96376.1 - 1.6e-07 31.6 0.0 3.3e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXS96376.1 - 2.2e-06 27.6 0.0 3.8e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXS96376.1 - 0.00093 19.3 0.0 0.002 18.3 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KXS96376.1 - 0.044 14.4 0.0 0.089 13.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Rick_17kDa_Anti PF05433.15 KXS96377.1 - 2.1e-05 24.3 7.0 3.9e-05 23.4 7.0 1.5 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.6 KXS96377.1 - 0.00023 20.8 8.0 0.00045 19.9 8.0 1.5 1 0 0 1 1 1 1 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 KXS96377.1 - 0.00071 19.5 2.3 0.0015 18.5 2.3 1.5 1 0 0 1 1 1 1 Glycine zipper DUF533 PF04391.12 KXS96377.1 - 0.13 11.8 0.1 0.21 11.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Transgly_assoc PF04226.13 KXS96377.1 - 5.1 7.4 5.9 20 5.6 5.9 1.8 1 1 1 2 2 2 0 Transglycosylase associated protein Fungal_trans PF04082.18 KXS96378.1 - 2.4e-11 43.2 0.0 1.1e-10 41.1 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain RabGAP-TBC PF00566.18 KXS96379.1 - 8.6e-49 166.1 0.0 1.5e-48 165.3 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain TSC22 PF01166.18 KXS96379.1 - 1.1 9.6 6.5 2.8 8.3 0.3 3.2 2 1 0 2 2 2 0 TSC-22/dip/bun family CENP-H PF05837.12 KXS96379.1 - 1.3 9.5 41.8 1.4 9.4 10.0 4.0 3 1 0 3 3 3 0 Centromere protein H (CENP-H) ERM PF00769.19 KXS96379.1 - 6.1 6.6 46.2 0.0091 15.8 10.7 3.5 3 0 0 3 3 3 0 Ezrin/radixin/moesin family Ceramidase_alk PF04734.13 KXS96380.1 - 5.5e-219 728.0 0.0 6.4e-219 727.8 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 KXS96380.1 - 2.6e-58 196.6 0.1 5.1e-58 195.7 0.1 1.4 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal ZF-HD_dimer PF04770.12 KXS96381.1 - 0.12 12.7 2.7 0.2 12.0 2.7 1.3 1 0 0 1 1 1 0 ZF-HD protein dimerisation region Meth_synt_2 PF01717.18 KXS96382.1 - 0.00017 20.9 0.0 0.002 17.5 0.0 2.1 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain F-box-like PF12937.7 KXS96383.1 - 0.0033 17.3 0.0 0.012 15.5 0.0 1.9 1 0 0 1 1 1 1 F-box-like FMN_dh PF01070.18 KXS96384.1 - 5.7e-111 370.9 0.0 7.3e-111 370.5 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KXS96384.1 - 5.5e-18 64.9 0.0 9.9e-18 64.1 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KXS96384.1 - 1.4e-05 24.5 0.0 2.1e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KXS96384.1 - 9.4e-05 21.6 0.3 0.00033 19.7 0.3 2.0 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KXS96384.1 - 0.00026 20.5 0.0 0.00049 19.6 0.0 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 KXS96384.1 - 0.042 13.1 0.1 0.34 10.2 0.1 2.0 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG FMO-like PF00743.19 KXS96385.1 - 6.9e-12 44.6 0.0 1.2e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KXS96385.1 - 1.2e-11 44.4 0.0 3.9e-11 42.7 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXS96385.1 - 1.7e-09 37.7 0.0 2.9e-08 33.8 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXS96385.1 - 2e-09 37.2 0.0 3e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXS96385.1 - 1.6e-08 34.0 0.0 1e-05 24.8 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein K_oxygenase PF13434.6 KXS96385.1 - 1e-06 28.2 0.0 4.1e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KXS96385.1 - 5.7e-05 23.2 0.7 0.0034 17.4 0.2 3.5 3 1 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KXS96385.1 - 0.0013 17.9 0.0 0.0036 16.4 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KXS96385.1 - 0.0013 18.4 0.0 0.008 15.8 0.0 2.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXS96385.1 - 0.0017 18.9 0.5 0.48 11.0 0.5 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXS96385.1 - 0.05 12.3 1.0 0.18 10.5 0.3 2.0 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_7 PF13241.6 KXS96385.1 - 0.17 12.3 0.0 17 5.9 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding adh_short PF00106.25 KXS96386.1 - 8.7e-40 136.3 0.0 1.5e-39 135.5 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS96386.1 - 3.8e-26 92.1 0.1 5.5e-26 91.6 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS96386.1 - 2.7e-10 40.5 0.1 1.4e-09 38.1 0.1 2.0 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KXS96386.1 - 3e-05 24.0 0.0 5.3e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXS96386.1 - 0.00028 20.4 0.0 0.00046 19.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KXS96386.1 - 0.0096 15.0 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KXS96386.1 - 0.027 13.5 0.0 0.043 12.8 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Pkinase PF00069.25 KXS96387.1 - 1.7e-19 70.3 0.0 4.8e-16 58.9 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXS96387.1 - 4.5e-08 32.7 0.0 9.2e-07 28.4 0.0 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase Peptidase_M28 PF04389.17 KXS96388.1 - 8.7e-41 139.8 0.0 1.3e-40 139.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KXS96388.1 - 4.6e-15 55.4 1.6 7.9e-15 54.7 0.7 1.9 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 KXS96388.1 - 6.8e-05 22.7 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 KXS96388.1 - 0.09 11.8 0.0 0.34 9.9 0.0 1.7 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase Peptidase_M28 PF04389.17 KXS96389.1 - 8.7e-41 139.8 0.0 1.3e-40 139.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KXS96389.1 - 4.6e-15 55.4 1.6 7.9e-15 54.7 0.7 1.9 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 KXS96389.1 - 6.8e-05 22.7 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 KXS96389.1 - 0.09 11.8 0.0 0.34 9.9 0.0 1.7 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase Peptidase_M28 PF04389.17 KXS96390.1 - 8.7e-41 139.8 0.0 1.3e-40 139.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KXS96390.1 - 4.6e-15 55.4 1.6 7.9e-15 54.7 0.7 1.9 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 KXS96390.1 - 6.8e-05 22.7 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 KXS96390.1 - 0.09 11.8 0.0 0.34 9.9 0.0 1.7 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase p450 PF00067.22 KXS96391.1 - 1.9e-09 36.8 0.0 2.4e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2347 PF09804.9 KXS96391.1 - 0.068 12.7 0.0 0.4 10.2 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) p450 PF00067.22 KXS96392.1 - 1.9e-09 36.8 0.0 2.4e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2347 PF09804.9 KXS96392.1 - 0.068 12.7 0.0 0.4 10.2 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) Peptidase_M28 PF04389.17 KXS96393.1 - 8.7e-41 139.8 0.0 1.3e-40 139.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KXS96393.1 - 4.6e-15 55.4 1.6 7.9e-15 54.7 0.7 1.9 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 KXS96393.1 - 6.8e-05 22.7 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 KXS96393.1 - 0.09 11.8 0.0 0.34 9.9 0.0 1.7 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase Peptidase_M28 PF04389.17 KXS96394.1 - 8.7e-41 139.8 0.0 1.3e-40 139.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KXS96394.1 - 4.6e-15 55.4 1.6 7.9e-15 54.7 0.7 1.9 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 KXS96394.1 - 6.8e-05 22.7 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 KXS96394.1 - 0.09 11.8 0.0 0.34 9.9 0.0 1.7 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase p450 PF00067.22 KXS96395.1 - 1.9e-09 36.8 0.0 2.4e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2347 PF09804.9 KXS96395.1 - 0.068 12.7 0.0 0.4 10.2 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) Peptidase_S10 PF00450.22 KXS96396.1 - 4.2e-85 286.7 0.1 1.1e-84 285.3 0.1 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase GST_C_2 PF13410.6 KXS96396.1 - 0.00076 19.5 0.0 0.0022 18.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KXS96396.1 - 0.0055 17.1 0.0 0.014 15.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXS96396.1 - 0.0061 16.8 0.0 0.029 14.6 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MFS_1 PF07690.16 KXS96406.1 - 5.5e-25 88.0 24.6 5.5e-25 88.0 24.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily 7tm_7 PF08395.12 KXS96406.1 - 1.7 7.7 9.4 0.35 10.0 5.4 1.8 2 0 0 2 2 2 0 7tm Chemosensory receptor ADH_N PF08240.12 KXS96407.1 - 1.1e-24 86.4 3.7 1.1e-24 86.4 3.7 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXS96407.1 - 3.5e-18 65.9 0.2 6.3e-18 65.0 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KXS96407.1 - 0.005 16.1 0.1 0.014 14.7 0.1 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 KXS96407.1 - 0.031 15.3 0.0 0.056 14.5 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ADH_N PF08240.12 KXS96408.1 - 1.1e-24 86.4 3.7 1.1e-24 86.4 3.7 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXS96408.1 - 3.5e-18 65.9 0.2 6.3e-18 65.0 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KXS96408.1 - 0.005 16.1 0.1 0.014 14.7 0.1 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 KXS96408.1 - 0.031 15.3 0.0 0.056 14.5 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Semialdhyde_dhC PF02774.18 KXS96409.1 - 1.3e-39 136.2 0.0 1.8e-39 135.7 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 KXS96409.1 - 2.3e-28 99.1 0.0 8.8e-28 97.2 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.16 KXS96409.1 - 0.079 13.7 0.0 0.23 12.2 0.0 1.9 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Sacchrp_dh_NADP PF03435.18 KXS96409.1 - 0.097 12.9 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 KXS96409.1 - 0.14 12.3 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Pkinase PF00069.25 KXS96410.1 - 2.5e-26 92.6 0.0 3.1e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS96410.1 - 6.7e-14 51.8 0.0 9.3e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXS96410.1 - 4.2e-09 35.7 0.0 6.3e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXS96410.1 - 0.00018 21.5 0.0 0.0014 18.6 0.0 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family Glyco_hydro_17 PF00332.18 KXS96411.1 - 3.5e-05 23.6 0.3 6.1e-05 22.8 0.3 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 adh_short_C2 PF13561.6 KXS96413.1 - 9.5e-62 208.6 0.3 1.1e-61 208.4 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS96413.1 - 1.6e-52 177.8 0.3 1.9e-52 177.6 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS96413.1 - 8.6e-16 58.4 0.0 1.2e-15 57.9 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS96413.1 - 1.1e-06 28.4 0.1 2.8e-06 27.0 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KXS96413.1 - 0.0038 16.7 0.0 0.014 14.7 0.0 1.8 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.19 KXS96413.1 - 0.065 12.6 0.1 0.13 11.5 0.1 1.7 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SWIRM-assoc_3 PF16498.5 KXS96413.1 - 0.49 10.7 1.9 24 5.3 0.4 2.8 3 0 0 3 3 3 0 SWIRM-associated domain at the C-terminal IFT57 PF10498.9 KXS96414.1 - 0.69 8.8 45.0 0.16 10.9 13.6 3.4 1 1 2 3 3 3 0 Intra-flagellar transport protein 57 Leu_zip PF15294.6 KXS96414.1 - 1 8.8 46.8 0.07 12.6 21.0 3.0 1 1 2 3 3 3 0 Leucine zipper GDNF PF02351.16 KXS96414.1 - 5.7 8.0 12.0 2.3 9.2 0.2 4.1 3 1 0 3 3 3 0 GDNF/GAS1 domain Bac_rhodopsin PF01036.18 KXS96415.1 - 6.8e-61 205.7 12.3 7.9e-61 205.5 12.3 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Arteri_Gl PF00951.18 KXS96415.1 - 0.0016 18.3 2.0 0.0036 17.1 2.0 1.5 1 0 0 1 1 1 1 Arterivirus GL envelope glycoprotein DUF4199 PF13858.6 KXS96415.1 - 2.5 8.5 7.6 0.25 11.7 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) MARVEL PF01284.23 KXS96415.1 - 8 6.5 17.9 0.16 12.0 1.7 2.8 2 1 1 3 3 3 0 Membrane-associating domain SQS_PSY PF00494.19 KXS96416.1 - 8.7e-60 202.4 0.0 1.4e-59 201.8 0.0 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase Cupin_2 PF07883.11 KXS96417.1 - 1.3e-06 28.0 0.0 2.5e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Cupin domain FYVE PF01363.21 KXS96418.1 - 0.0075 16.4 0.6 0.016 15.3 0.6 1.5 1 0 0 1 1 1 1 FYVE zinc finger CNDH2_M PF16869.5 KXS96418.1 - 0.042 14.6 0.7 0.042 14.6 0.7 2.9 3 2 0 3 3 3 0 PF16858 zf-RING_5 PF14634.6 KXS96418.1 - 0.24 11.4 5.4 0.57 10.2 5.4 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 KXS96418.1 - 0.37 11.2 5.4 0.82 10.1 5.4 1.6 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 KXS96418.1 - 9.7 6.3 11.6 0.72 9.9 6.7 1.7 2 0 0 2 2 2 0 RING-type zinc-finger Amino_oxidase PF01593.24 KXS96419.1 - 1.5e-16 60.8 1.0 2e-08 34.0 0.0 2.9 2 1 1 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXS96419.1 - 5.6e-13 48.9 0.1 4.8e-12 45.9 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXS96419.1 - 1.6e-11 44.4 0.8 9e-11 41.9 0.7 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXS96419.1 - 6.6e-11 42.0 0.2 6.9e-07 28.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXS96419.1 - 2.6e-07 30.1 5.2 2e-05 23.9 1.9 2.8 3 0 0 3 3 3 2 FAD binding domain HI0933_like PF03486.14 KXS96419.1 - 3.4e-06 26.0 0.0 0.0016 17.2 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.7 KXS96419.1 - 0.00022 20.7 0.1 0.0012 18.3 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXS96419.1 - 0.00093 18.5 0.2 0.0035 16.6 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXS96419.1 - 0.0011 18.2 0.6 0.0025 17.1 0.6 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 KXS96419.1 - 0.0017 17.7 0.2 0.0062 15.8 0.3 1.8 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 KXS96419.1 - 0.002 17.3 2.8 0.0037 16.4 0.6 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KXS96419.1 - 0.0027 17.7 0.7 0.091 12.7 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KXS96419.1 - 0.0034 16.5 0.3 0.16 11.0 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.27 KXS96419.1 - 0.0052 17.3 4.8 0.21 12.2 1.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 KXS96419.1 - 0.0091 15.4 0.5 0.74 9.1 0.1 2.2 2 0 0 2 2 2 1 GMC oxidoreductase AlaDh_PNT_C PF01262.21 KXS96419.1 - 0.056 12.7 0.3 0.098 11.9 0.3 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KXS96419.1 - 0.071 13.0 0.6 0.12 12.3 0.6 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDI PF00996.18 KXS96419.1 - 0.12 10.9 0.0 5.6 5.4 0.0 2.1 2 0 0 2 2 2 0 GDP dissociation inhibitor Trp_halogenase PF04820.14 KXS96419.1 - 0.54 9.0 4.9 4.8 5.9 0.2 2.2 2 0 0 2 2 2 0 Tryptophan halogenase RPE65 PF03055.15 KXS96422.1 - 3.9e-127 425.3 0.0 4.5e-127 425.1 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein PPI_Ypi1 PF07491.11 KXS96422.1 - 0.052 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein phosphatase inhibitor PerB PF06590.11 KXS96422.1 - 0.13 12.8 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 PerB protein FAD-oxidase_C PF02913.19 KXS96423.1 - 8e-14 51.9 0.7 2.6e-10 40.4 0.1 2.0 1 1 1 2 2 2 2 FAD linked oxidases, C-terminal domain Git3 PF11710.8 KXS96425.1 - 4e-11 43.1 13.5 4.1e-08 33.2 13.5 2.2 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 KXS96425.1 - 2.4e-06 27.5 0.0 8.3e-06 25.8 0.0 1.9 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term Pepsin-I3 PF06394.13 KXS96426.1 - 0.17 12.1 0.1 0.3 11.3 0.1 1.3 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain ELP6 PF09807.9 KXS96427.1 - 4.7e-06 26.2 0.0 1.3e-05 24.7 0.0 1.7 1 1 1 2 2 2 2 Elongation complex protein 6 Elong_Iki1 PF10483.9 KXS96427.1 - 0.0078 15.8 0.3 0.0099 15.4 0.3 1.2 1 0 0 1 1 1 1 Elongator subunit Iki1 DUF2231 PF09990.9 KXS96432.1 - 1.1e-08 35.5 2.1 1.7e-08 34.8 2.1 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2231) DUF2231 PF09990.9 KXS96433.1 - 1e-08 35.5 2.1 1.5e-08 35.0 2.1 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2231) Folliculin PF11704.8 KXS96434.1 - 0.37 10.6 2.3 4.6 7.1 0.0 2.7 3 0 0 3 3 3 0 Vesicle coat protein involved in Golgi to plasma membrane transport HsbA PF12296.8 KXS96435.1 - 6.6e-18 65.3 9.8 1.1e-17 64.5 9.8 1.4 1 0 0 1 1 1 1 Hydrophobic surface binding protein A DUF1400 PF07176.11 KXS96435.1 - 0.027 14.8 1.9 1.7 9.0 0.1 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1400) MFS_1 PF07690.16 KXS96436.1 - 1.1e-37 129.8 26.2 1.1e-37 129.8 26.2 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily FeoB_C PF07664.12 KXS96436.1 - 0.043 13.5 1.9 5.6 6.7 0.0 3.9 4 0 0 4 4 4 0 Ferrous iron transport protein B C terminus SfLAP PF11139.8 KXS96436.1 - 0.071 12.5 4.9 0.78 9.1 0.1 3.2 3 1 0 3 3 3 0 Sap, sulfolipid-1-addressing protein Phage_holin_2_4 PF16082.5 KXS96436.1 - 0.093 12.5 0.1 2.6 7.8 0.1 2.8 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like DUF2975 PF11188.8 KXS96436.1 - 9.8 6.1 9.7 14 5.5 0.0 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF2975) FAD_syn PF06574.12 KXS96437.1 - 0.091 12.6 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 FAD synthetase CCDC-167 PF15188.6 KXS96438.1 - 0.04 14.3 0.2 0.063 13.6 0.2 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Porph_ging PF09697.10 KXS96439.1 - 0.15 12.6 0.0 0.27 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (Porph_ging) Fungal_trans PF04082.18 KXS96440.1 - 9.3e-23 80.6 0.8 2.4e-22 79.2 0.8 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS96440.1 - 1.2e-07 31.7 10.0 2.1e-07 30.9 10.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain KA1 PF02149.19 KXS96441.1 - 0.029 14.2 0.0 0.1 12.4 0.0 1.9 1 0 0 1 1 1 0 Kinase associated domain 1 DUF1127 PF06568.11 KXS96441.1 - 0.57 10.0 4.4 2 8.2 4.4 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1127) MFS_1 PF07690.16 KXS96443.1 - 1.5e-44 152.4 46.8 1.6e-38 132.6 20.2 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS96443.1 - 1.5e-07 30.6 0.9 1.5e-07 30.6 0.9 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter CGI-121 PF08617.10 KXS96444.1 - 5.7e-52 176.1 0.1 6.4e-52 175.9 0.1 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 4HBT_3 PF13622.6 KXS96445.1 - 2.6e-28 99.9 0.2 5.6e-28 98.8 0.2 1.5 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KXS96445.1 - 0.0068 16.3 0.3 2.1 8.2 0.1 2.9 3 0 0 3 3 3 2 Acyl-CoA thioesterase Abhydrolase_1 PF00561.20 KXS96446.1 - 3.2e-14 53.2 0.0 3.6e-14 53.0 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXS96446.1 - 2.6e-08 34.7 0.0 5.7e-08 33.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXS96446.1 - 3e-05 23.4 0.0 9.9e-05 21.7 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 CoA_transf_3 PF02515.17 KXS96448.1 - 3.2e-124 414.8 0.0 3.6e-124 414.6 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III Slx4 PF09494.10 KXS96457.1 - 2.3e-20 72.3 0.1 5.7e-20 71.0 0.1 1.7 1 1 0 1 1 1 1 Slx4 endonuclease AT_hook PF02178.19 KXS96457.1 - 1.3 9.2 21.5 1.4 9.0 4.4 4.7 3 0 0 3 3 3 0 AT hook motif Sugar_tr PF00083.24 KXS96458.1 - 1.2e-105 354.0 26.4 1.4e-105 353.8 26.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS96458.1 - 2e-25 89.5 42.6 2.6e-24 85.8 41.6 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 KXS96458.1 - 0.18 12.4 1.6 0.5 10.9 1.6 1.7 1 0 0 1 1 1 0 Phage holin family 2 TANGO2 PF05742.12 KXS96459.1 - 0.11 12.5 0.2 0.24 11.4 0.1 1.6 1 1 1 2 2 2 0 Transport and Golgi organisation 2 NUDIX PF00293.28 KXS96460.1 - 9.5e-08 32.2 0.1 3e-07 30.5 0.1 2.0 1 1 0 1 1 1 1 NUDIX domain FAD_binding_7 PF03441.14 KXS96461.1 - 1.9e-79 265.8 0.8 3.4e-79 265.0 0.8 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KXS96461.1 - 3e-38 131.4 0.1 4.8e-38 130.7 0.1 1.3 1 0 0 1 1 1 1 DNA photolyase DUF1441 PF07278.11 KXS96461.1 - 0.12 12.3 0.1 0.37 10.7 0.1 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF1441) Zip PF02535.22 KXS96462.1 - 1.7e-48 165.6 4.8 2.2e-48 165.2 4.8 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Cutinase PF01083.22 KXS96462.1 - 5.6e-45 153.5 1.3 9e-45 152.8 1.3 1.3 1 0 0 1 1 1 1 Cutinase Glyco_transf_28 PF03033.20 KXS96462.1 - 0.0092 16.0 0.0 0.022 14.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PE-PPE PF08237.11 KXS96462.1 - 0.016 14.7 0.1 0.047 13.2 0.1 1.7 1 0 0 1 1 1 0 PE-PPE domain FMN_dh PF01070.18 KXS96463.1 - 1.8e-116 389.0 0.0 2.1e-116 388.8 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KXS96463.1 - 2.4e-08 33.4 0.1 2.3e-07 30.1 0.0 2.1 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KXS96463.1 - 4.9e-06 25.9 0.1 2.5e-05 23.6 0.0 1.9 2 0 0 2 2 2 1 Conserved region in glutamate synthase His_biosynth PF00977.21 KXS96463.1 - 0.0089 15.5 0.0 0.028 13.9 0.0 1.7 2 0 0 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.14 KXS96463.1 - 0.021 14.1 0.1 0.6 9.4 0.1 2.2 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG CutC PF03932.14 KXS96463.1 - 0.15 11.5 0.1 0.25 10.8 0.1 1.3 1 0 0 1 1 1 0 CutC family Med3 PF11593.8 KXS96465.1 - 0.015 14.5 2.9 0.02 14.1 2.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal ApbA PF02558.16 KXS96467.1 - 4.3e-31 107.6 0.0 6.4e-31 107.1 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KXS96467.1 - 1.1e-28 100.0 0.1 1.8e-28 99.3 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal NAD_binding_7 PF13241.6 KXS96467.1 - 0.019 15.4 0.0 0.058 13.8 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 KXS96467.1 - 0.098 12.9 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF1563 PF07599.11 KXS96468.1 - 0.063 13.4 1.5 0.11 12.7 0.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1563) DUF5473 PF17567.2 KXS96469.1 - 0.057 13.7 0.1 0.07 13.4 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5473) IBR PF01485.21 KXS96476.1 - 2.3e-11 43.7 27.6 8.2e-07 29.2 12.1 4.7 4 1 0 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 KXS96476.1 - 0.02 14.7 3.8 0.02 14.7 3.8 5.1 4 2 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) DUF218 PF02698.17 KXS96478.1 - 2.9e-07 30.5 0.0 3.6e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 DUF218 domain Nas2_N PF18265.1 KXS96479.1 - 4.7e-29 100.1 0.1 7.1e-29 99.6 0.1 1.3 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 KXS96479.1 - 2.6e-13 49.6 0.1 5e-13 48.7 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KXS96479.1 - 8.7e-09 35.6 0.0 2e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KXS96479.1 - 5.3e-07 29.9 0.0 1.1e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 KXS96479.1 - 5.7e-06 26.7 0.0 1.1e-05 25.8 0.0 1.4 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain Flg_hook PF02120.16 KXS96480.1 - 0.033 14.1 0.0 0.071 13.0 0.0 1.5 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK NAD_binding_1 PF00175.21 KXS96481.1 - 1.1e-30 106.4 0.0 1.8e-30 105.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KXS96481.1 - 5.8e-26 90.7 0.0 1e-25 89.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KXS96481.1 - 8e-08 32.5 0.0 0.00059 20.0 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 KXS96481.1 - 0.0096 16.1 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain Nitrate_red_gam PF02665.14 KXS96482.1 - 0.0098 15.5 0.1 0.011 15.3 0.1 1.1 1 0 0 1 1 1 1 Nitrate reductase gamma subunit Neurensin PF14927.6 KXS96482.1 - 0.12 12.1 0.1 0.14 11.8 0.1 1.1 1 0 0 1 1 1 0 Neurensin MMM1 PF10296.9 KXS96483.1 - 7.8e-05 21.9 0.0 0.00032 19.9 0.0 1.8 2 0 0 2 2 2 1 Maintenance of mitochondrial morphology protein 1 K_trans PF02705.16 KXS96484.1 - 2.9e-176 587.1 12.9 3.5e-176 586.8 12.9 1.1 1 0 0 1 1 1 1 K+ potassium transporter PAF-AH_p_II PF03403.13 KXS96485.1 - 7.3e-45 153.1 0.0 2.8e-40 138.0 0.0 2.2 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Ras PF00071.22 KXS96485.1 - 1e-40 139.0 0.0 1.7e-35 122.0 0.0 2.6 2 1 0 2 2 2 2 Ras family Roc PF08477.13 KXS96485.1 - 2e-25 89.3 0.0 5.2e-24 84.8 0.0 2.4 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXS96485.1 - 2.3e-08 33.7 0.0 2.5e-07 30.3 0.0 2.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KXS96485.1 - 7.6e-06 25.6 0.0 1.3e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Chlorophyllase2 PF12740.7 KXS96485.1 - 6.2e-05 22.0 0.0 0.00023 20.2 0.0 1.8 2 0 0 2 2 2 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KXS96485.1 - 0.00023 20.5 0.0 0.0097 15.2 0.0 2.4 2 0 0 2 2 2 1 Serine aminopeptidase, S33 RsgA_GTPase PF03193.16 KXS96485.1 - 0.0007 19.5 0.1 0.18 11.7 0.0 2.4 1 1 1 2 2 2 1 RsgA GTPase Chlorophyllase PF07224.11 KXS96485.1 - 0.0011 18.1 0.0 0.0019 17.3 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase AAA_33 PF13671.6 KXS96485.1 - 0.0018 18.4 0.0 0.0047 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KXS96485.1 - 0.0051 16.9 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KXS96485.1 - 0.0087 15.4 0.0 0.017 14.5 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 KXS96485.1 - 0.014 15.7 0.7 0.079 13.3 0.1 2.5 3 0 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 KXS96485.1 - 0.031 14.6 0.0 0.076 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KXS96485.1 - 0.037 14.5 0.0 0.17 12.4 0.0 2.1 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.12 KXS96485.1 - 0.077 12.9 0.1 0.37 10.7 0.0 2.1 2 0 0 2 2 2 0 NACHT domain 4HBT PF03061.22 KXS96486.1 - 5.6e-06 26.6 0.0 8.7e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily MaoC_dehydratas PF01575.19 KXS96486.1 - 0.17 11.5 0.0 0.35 10.4 0.0 1.5 2 0 0 2 2 2 0 MaoC like domain Polysacc_deac_1 PF01522.21 KXS96487.1 - 8.9e-23 80.5 0.0 2.4e-22 79.1 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide deacetylase Ribonuc_2-5A PF06479.12 KXS96487.1 - 0.0053 16.9 0.1 0.18 12.0 0.1 2.3 2 0 0 2 2 2 1 Ribonuclease 2-5A Polysacc_deac_2 PF04748.13 KXS96487.1 - 0.041 13.1 0.0 0.071 12.3 0.0 1.3 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase DUF4263 PF14082.6 KXS96487.1 - 0.15 12.4 0.0 0.2 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4263) Effector_1 PF04518.12 KXS96487.1 - 0.16 11.0 0.0 0.22 10.6 0.0 1.1 1 0 0 1 1 1 0 Effector from type III secretion system Catalase PF00199.19 KXS96488.1 - 1.1e-168 561.3 0.4 1.5e-168 560.9 0.4 1.2 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KXS96488.1 - 2.7e-19 69.1 0.1 4.9e-19 68.3 0.1 1.4 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase_C PF18011.1 KXS96488.1 - 3.6e-10 39.7 0.1 6.4e-10 38.9 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 KXS96488.1 - 4.2e-10 39.7 0.0 9.2e-10 38.6 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family Corona_3 PF04694.12 KXS96488.1 - 0.13 12.6 0.0 0.39 11.1 0.0 1.7 2 0 0 2 2 2 0 Coronavirus ORF3 protein adh_short PF00106.25 KXS96495.1 - 2e-18 66.5 0.0 2.6e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS96495.1 - 6.9e-18 65.1 0.0 9.4e-18 64.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF460 PF04312.13 KXS96495.1 - 0.0032 17.2 0.0 0.0075 16.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF460) KR PF08659.10 KXS96495.1 - 0.045 13.7 0.1 0.13 12.1 0.1 1.8 1 1 1 2 2 2 0 KR domain STALD PF18185.1 KXS96495.1 - 0.085 12.2 0.1 1.9 7.8 0.0 2.2 2 0 0 2 2 2 0 Sir2- and TIR-associating SLOG family SIS PF01380.22 KXS96495.1 - 0.15 11.9 0.0 1.8 8.4 0.0 2.1 2 0 0 2 2 2 0 SIS domain Ada3 PF10198.9 KXS96496.1 - 4.2e-42 143.4 0.6 4.2e-42 143.4 0.6 2.3 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 Cdh1_DBD_1 PF18196.1 KXS96496.1 - 1.4 9.3 7.6 4.8 7.5 7.0 2.2 2 0 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 V_ATPase_I PF01496.19 KXS96496.1 - 4.8 5.0 6.5 2.5 5.9 0.0 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family COX6C PF02937.15 KXS96497.1 - 0.11 12.6 0.0 0.13 12.4 0.0 1.0 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc PhoD PF09423.10 KXS96498.1 - 0.021 13.8 0.1 0.022 13.8 0.1 1.0 1 0 0 1 1 1 0 PhoD-like phosphatase RGS PF00615.19 KXS96499.1 - 3.3e-11 43.5 0.0 6.9e-09 36.0 0.0 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain ABM PF03992.16 KXS96500.1 - 7.7e-05 22.7 0.0 0.00011 22.2 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase ABM PF03992.16 KXS96501.1 - 1e-08 35.2 0.1 1.5e-08 34.6 0.1 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF1642 PF07852.11 KXS96501.1 - 0.017 15.7 0.7 0.025 15.2 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1642) Actin PF00022.19 KXS96502.1 - 1.2e-19 70.2 0.0 6.2e-11 41.5 0.0 3.1 3 0 0 3 3 3 3 Actin PilM_2 PF11104.8 KXS96502.1 - 0.1 11.6 0.0 11 4.9 0.0 2.2 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; Peptidase_S8 PF00082.22 KXS96503.1 - 5.1e-27 94.9 7.7 1.2e-26 93.7 7.7 1.5 1 1 0 1 1 1 1 Subtilase family Aldo_ket_red PF00248.21 KXS96504.1 - 1.7e-42 145.7 0.0 2.3e-42 145.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Ribonuc_L-PSP PF01042.21 KXS96504.1 - 1.7e-13 50.7 0.0 3.7e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Endoribonuclease L-PSP Herpes_LP PF03363.13 KXS96504.1 - 0.2 11.4 0.6 0.5 10.1 0.6 1.6 1 1 0 1 1 1 0 Herpesvirus leader protein Epimerase PF01370.21 KXS96505.1 - 1.7e-15 57.2 0.0 2.2e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXS96505.1 - 1e-12 48.4 2.1 1.4e-12 47.9 2.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXS96505.1 - 8.3e-09 35.3 1.9 1.3e-08 34.8 1.1 1.6 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.19 KXS96505.1 - 4.8e-08 32.4 0.0 3e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KXS96505.1 - 3.1e-06 26.5 0.7 2e-05 23.8 0.7 1.9 1 1 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KXS96505.1 - 6.7e-06 25.7 0.4 4.5e-05 23.0 0.1 2.3 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 KXS96505.1 - 0.001 19.3 0.3 0.0027 17.9 0.2 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 KXS96505.1 - 0.0012 19.1 0.7 0.0051 17.1 0.3 1.9 1 1 1 2 2 2 1 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 KXS96505.1 - 0.0031 17.1 0.0 0.0052 16.4 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain adh_short PF00106.25 KXS96505.1 - 0.0055 16.2 0.4 0.0084 15.6 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase ApbA PF02558.16 KXS96505.1 - 0.01 15.5 0.1 0.032 13.9 0.1 1.9 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.15 KXS96505.1 - 0.016 15.3 0.0 0.031 14.4 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.21 KXS96505.1 - 0.048 12.9 0.3 0.076 12.3 0.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DapB_N PF01113.20 KXS96505.1 - 0.05 13.7 0.3 0.14 12.3 0.3 1.9 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Glyco_hydro_20 PF00728.22 KXS96506.1 - 4.1e-31 108.7 0.3 2.3e-30 106.2 0.3 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 KXS96506.1 - 1.4e-05 25.9 0.0 3.3e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 CBM_4_9 PF02018.17 KXS96506.1 - 0.014 15.6 0.4 1.6 9.0 0.0 2.6 2 0 0 2 2 2 0 Carbohydrate binding domain RES PF08808.11 KXS96507.1 - 0.032 14.1 0.0 0.04 13.8 0.0 1.2 1 0 0 1 1 1 0 RES domain Chitin_synth_1 PF01644.17 KXS96508.1 - 1.6e-68 229.8 0.0 2.5e-68 229.2 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KXS96508.1 - 6.1e-28 96.6 0.0 1.3e-27 95.5 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KXS96508.1 - 4.6e-21 75.0 2.9 8.4e-19 67.6 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase PLDc_2 PF13091.6 KXS96508.1 - 2.3e-15 56.6 0.0 7.5e-15 55.0 0.0 1.9 2 0 0 2 2 2 1 PLD-like domain Glyco_trans_2_3 PF13632.6 KXS96508.1 - 6.4e-08 32.8 4.6 3.6e-07 30.3 4.6 2.3 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Regulator_TrmB PF11495.8 KXS96508.1 - 0.012 14.8 0.0 0.024 13.8 0.0 1.4 1 0 0 1 1 1 0 Archaeal transcriptional regulator TrmB LRR_4 PF12799.7 KXS96509.1 - 0.014 15.8 0.3 0.21 12.0 0.3 2.9 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) zf-RING_2 PF13639.6 KXS96510.1 - 2.5e-10 40.5 4.1 4.9e-10 39.6 4.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KXS96510.1 - 3.9e-07 29.7 2.3 1.1e-06 28.3 2.3 1.8 1 1 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 KXS96510.1 - 4.9e-06 26.7 2.7 1.2e-05 25.4 2.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KXS96510.1 - 4.9e-06 26.3 4.4 1.4e-05 24.8 4.4 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS96510.1 - 1e-05 25.3 2.3 2e-05 24.3 2.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXS96510.1 - 2.7e-05 24.0 2.7 5e-05 23.2 2.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KXS96510.1 - 0.00044 20.3 0.7 0.00099 19.1 0.7 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 KXS96510.1 - 0.0018 18.3 4.2 0.0043 17.1 4.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KXS96510.1 - 0.0077 16.1 3.8 0.016 15.0 3.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KXS96510.1 - 0.012 15.5 2.1 0.024 14.5 2.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 KXS96510.1 - 0.083 12.8 3.2 0.17 11.8 3.2 1.6 1 0 0 1 1 1 0 PHD-finger zf-UDP PF14569.6 KXS96510.1 - 0.11 12.6 1.1 0.31 11.2 1.1 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING-like PF08746.11 KXS96510.1 - 0.12 12.7 0.9 0.28 11.5 0.9 1.6 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 KXS96510.1 - 0.17 11.7 2.6 0.34 10.7 2.6 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain LapA_dom PF06305.11 KXS96510.1 - 2.1 8.2 3.7 0.88 9.4 0.9 1.9 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain MatE PF01554.18 KXS96511.1 - 3.3e-07 30.1 1.8 3.3e-07 30.1 1.8 3.5 4 0 0 4 4 4 2 MatE Polysacc_synt_C PF14667.6 KXS96511.1 - 1.6e-05 25.0 3.4 1.6e-05 25.0 3.4 3.9 2 1 2 4 4 4 1 Polysaccharide biosynthesis C-terminal domain DUF4630 PF15443.6 KXS96511.1 - 0.029 14.6 1.1 4 7.6 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4630) Nop PF01798.18 KXS96512.1 - 2.5e-81 272.5 0.1 2.5e-81 272.5 0.1 2.0 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KXS96512.1 - 1e-21 77.1 3.7 1e-21 77.1 3.7 2.3 2 0 0 2 2 2 1 NOP5NT (NUC127) domain BSP_II PF05432.11 KXS96512.1 - 9.3 5.8 24.2 20 4.8 24.2 1.5 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Nup35_RRM PF05172.13 KXS96513.1 - 0.00015 21.7 0.0 0.0003 20.7 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Dynactin PF12455.8 KXS96514.1 - 1.1e-101 339.9 11.7 1.1e-101 339.9 11.7 3.4 3 1 1 4 4 4 1 Dynein associated protein CAP_GLY PF01302.25 KXS96514.1 - 1.1e-24 86.1 1.0 1.8e-24 85.5 1.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain NODP PF07684.12 KXS96514.1 - 0.1 12.8 0.3 0.29 11.3 0.3 1.7 1 0 0 1 1 1 0 NOTCH protein Aldo_ket_red PF00248.21 KXS96515.1 - 1.7e-48 165.3 0.1 3.8e-48 164.2 0.1 1.5 1 1 0 1 1 1 1 Aldo/keto reductase family SSP160 PF06933.11 KXS96516.1 - 0.5 8.5 21.6 0.56 8.3 21.6 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 AAA_18 PF13238.6 KXS96518.1 - 2.8e-05 24.7 0.0 0.00026 21.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain PRK PF00485.18 KXS96518.1 - 0.00012 21.9 0.0 0.006 16.3 0.0 2.2 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family CPT PF07931.12 KXS96518.1 - 0.00067 19.6 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_16 PF13191.6 KXS96518.1 - 0.018 15.5 0.0 0.031 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 KXS96518.1 - 0.062 13.8 0.0 0.2 12.1 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 KXS96518.1 - 0.089 13.0 0.0 1 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain TPR_17 PF13431.6 KXS96519.1 - 2.7e-06 27.4 1.1 0.002 18.4 0.2 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXS96519.1 - 0.0047 17.4 4.2 0.028 14.9 0.1 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat YrbL-PhoP_reg PF10707.9 KXS96519.1 - 0.0053 16.3 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL TPR_11 PF13414.6 KXS96519.1 - 0.006 16.2 1.1 11 5.8 0.0 4.0 4 0 0 4 4 4 1 TPR repeat TPR_14 PF13428.6 KXS96519.1 - 0.047 14.5 2.1 3.7 8.6 0.1 3.9 2 1 0 2 2 2 0 Tetratricopeptide repeat TFIIA_gamma_N PF02268.16 KXS96519.1 - 0.15 12.1 0.7 0.73 9.9 0.0 2.6 4 0 0 4 4 4 0 Transcription initiation factor IIA, gamma subunit, helical domain TPR_12 PF13424.6 KXS96519.1 - 1.5 9.2 12.4 0.63 10.4 0.4 4.2 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF1741 PF08427.10 KXS96521.1 - 2.1e-79 266.5 1.0 4.3e-79 265.5 1.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) DUF3071 PF11268.8 KXS96521.1 - 0.019 15.1 0.0 0.041 13.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3071) DUF2178 PF09946.9 KXS96521.1 - 0.035 14.3 0.1 0.1 12.8 0.1 1.7 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) AlaDh_PNT_N PF05222.15 KXS96521.1 - 0.083 13.2 0.1 0.17 12.1 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, N-terminal domain Es2 PF09751.9 KXS96521.1 - 0.097 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Nuclear protein Es2 DUF726 PF05277.12 KXS96522.1 - 2.1e-123 411.6 3.4 2.1e-123 411.6 3.4 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF726) Thioesterase PF00975.20 KXS96522.1 - 0.00056 20.1 0.0 0.00056 20.1 0.0 2.2 3 0 0 3 3 3 1 Thioesterase domain Hydrolase_4 PF12146.8 KXS96522.1 - 0.046 13.0 0.0 0.097 11.9 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXS96522.1 - 0.54 10.8 0.0 0.54 10.8 0.0 2.5 2 1 0 3 3 3 0 Alpha/beta hydrolase family SPO22 PF08631.10 KXS96523.1 - 1.4e-27 96.9 7.3 6.4e-27 94.7 0.3 3.7 3 1 0 5 5 5 2 Meiosis protein SPO22/ZIP4 like 4HBT PF03061.22 KXS96524.1 - 2e-12 47.3 0.1 3.4e-12 46.6 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 KXS96524.1 - 3.6e-06 27.4 0.1 1.3e-05 25.6 0.1 1.8 1 1 0 1 1 1 1 Thioesterase-like superfamily VIR_N PF15912.5 KXS96524.1 - 0.045 13.4 0.1 0.058 13.0 0.1 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal CAP_N PF01213.19 KXS96524.1 - 0.19 11.2 0.9 0.3 10.5 0.9 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal 4HBT PF03061.22 KXS96525.1 - 9.3e-13 48.3 0.1 1.6e-12 47.6 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 KXS96525.1 - 0.00011 22.5 0.0 0.00013 22.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily MSC PF09402.10 KXS96526.1 - 0.071 12.5 4.4 0.27 10.7 4.4 1.9 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain DUF2543 PF10820.8 KXS96526.1 - 0.39 10.9 2.4 0.57 10.4 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2543) SATase_N PF06426.14 KXS96526.1 - 7 7.1 8.2 28 5.2 0.0 3.9 3 1 0 3 3 3 0 Serine acetyltransferase, N-terminal PAXIP1_C PF15364.6 KXS96527.1 - 0.017 15.4 2.9 0.042 14.2 0.0 2.5 2 1 1 3 3 3 0 PAXIP1-associated-protein-1 C term PTIP binding protein Trehalase PF01204.18 KXS96528.1 - 5.4e-11 42.0 0.0 8.2e-11 41.4 0.0 1.2 1 0 0 1 1 1 1 Trehalase Glyco_hydro_63 PF03200.16 KXS96528.1 - 2.6e-05 23.2 4.8 0.0054 15.5 0.0 4.2 2 2 1 4 4 4 2 Glycosyl hydrolase family 63 C-terminal domain DUF1674 PF07896.12 KXS96529.1 - 4.3e-21 75.1 3.9 1.2e-20 73.7 3.9 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) HATPase_c_4 PF13749.6 KXS96530.1 - 0.016 15.4 1.6 2.9 8.1 0.2 2.8 2 0 0 2 2 2 0 Putative ATP-dependent DNA helicase recG C-terminal ATP-synt_Eps PF04627.13 KXS96530.1 - 0.22 11.5 0.3 1.4 9.0 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ATP synthase epsilon chain PH_9 PF15410.6 KXS96531.1 - 0.0067 16.8 0.0 0.096 13.1 0.0 2.2 1 1 1 2 2 2 1 Pleckstrin homology domain KH_1 PF00013.29 KXS96532.1 - 5.5e-45 151.0 12.5 2.9e-15 55.8 0.6 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KXS96532.1 - 4.9e-12 45.5 8.0 0.0015 18.3 0.3 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KXS96532.1 - 3.9e-08 33.1 6.9 0.058 13.3 0.1 3.4 3 0 0 3 3 3 3 KH domain MOEP19 PF16005.5 KXS96532.1 - 0.00039 20.3 0.0 1.7 8.7 0.0 2.7 3 0 0 3 3 3 2 KH-like RNA-binding domain KH_5 PF13184.6 KXS96532.1 - 0.00055 20.0 6.2 0.15 12.2 0.2 3.4 3 0 0 3 3 3 2 NusA-like KH domain GRP PF07172.11 KXS96532.1 - 7.5 7.3 34.4 0.64 10.8 8.0 3.8 4 0 0 4 4 4 0 Glycine rich protein family SLAC1 PF03595.17 KXS96533.1 - 2.3e-12 46.8 5.7 5.3e-07 29.2 4.7 2.1 1 1 1 2 2 2 2 Voltage-dependent anion channel DUF2207 PF09972.9 KXS96533.1 - 1.1 8.0 2.4 1.4 7.6 2.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Podoplanin PF05808.11 KXS96534.1 - 0.0012 19.0 0.2 0.0012 19.0 0.2 2.3 2 1 0 2 2 2 1 Podoplanin LapA_dom PF06305.11 KXS96534.1 - 0.006 16.4 0.9 0.0098 15.7 0.9 1.3 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain Miga PF10265.9 KXS96534.1 - 0.0084 15.1 0.1 0.0094 15.0 0.1 1.0 1 0 0 1 1 1 1 Mitoguardin TMEM51 PF15345.6 KXS96534.1 - 0.042 13.7 0.0 0.045 13.6 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 MLANA PF14991.6 KXS96534.1 - 0.097 13.0 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein melan-A Acyl-CoA_dh_1 PF00441.24 KXS96535.1 - 7.3e-41 139.9 0.5 1.2e-40 139.1 0.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KXS96535.1 - 2.3e-22 79.0 0.2 4.1e-22 78.2 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 KXS96535.1 - 1.7e-19 69.7 0.2 3.5e-19 68.7 0.2 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 KXS96535.1 - 4.5e-17 62.7 0.0 1.4e-16 61.2 0.0 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KXS96535.1 - 2.5e-07 31.0 0.0 4.3e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain C6 PF01681.17 KXS96535.1 - 0.045 14.3 0.1 0.7 10.5 0.0 2.7 2 1 1 3 3 3 0 C6 domain p450 PF00067.22 KXS96536.1 - 3.3e-13 49.2 0.0 1.5e-12 47.0 0.0 1.9 2 0 0 2 2 2 1 Cytochrome P450 Sugar_tr PF00083.24 KXS96548.1 - 3.4e-130 434.9 29.8 3.9e-130 434.7 29.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS96548.1 - 8.1e-17 61.2 41.6 1.2e-16 60.6 35.7 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Dak1 PF02733.17 KXS96550.1 - 6.2e-109 363.6 7.4 8.5e-109 363.2 7.4 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 KXS96550.1 - 2.5e-47 161.0 2.9 6.9e-47 159.6 1.6 2.2 2 0 0 2 2 2 1 DAK2 domain His_Phos_1 PF00300.22 KXS96551.1 - 1e-08 35.1 0.0 2.5e-08 33.9 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SH3_5 PF08460.10 KXS96551.1 - 0.034 14.2 0.3 0.17 12.0 0.0 2.3 2 0 0 2 2 2 0 Bacterial SH3 domain Ribosomal_L22 PF00237.19 KXS96552.1 - 2.3e-42 143.4 0.1 3.2e-42 142.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Fibrillarin PF01269.17 KXS96553.1 - 8.9e-104 345.5 0.0 1.1e-103 345.3 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 KXS96553.1 - 1.6e-06 28.0 0.0 2.3e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 KXS96553.1 - 0.01 15.6 0.1 0.015 15.0 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 KXS96553.1 - 0.012 15.3 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F HMG_box PF00505.19 KXS96554.1 - 4.2e-11 43.1 2.1 1.8e-10 41.1 2.1 2.1 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KXS96554.1 - 2e-07 31.5 1.3 6.9e-07 29.8 1.3 2.0 1 0 0 1 1 1 1 HMG-box domain PolyA_pol_arg_C PF12626.7 KXS96554.1 - 0.01 15.9 0.5 0.031 14.3 0.5 1.8 1 0 0 1 1 1 0 Polymerase A arginine-rich C-terminus Chisel PF15355.6 KXS96554.1 - 0.58 10.4 3.5 0.81 10.0 0.7 2.4 2 0 0 2 2 2 0 Stretch-responsive small skeletal muscle X protein, Chisel PBP1_TM PF14812.6 KXS96554.1 - 0.84 10.0 10.3 0.38 11.2 6.1 2.6 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-C2H2 PF00096.26 KXS96555.1 - 1e-06 28.8 17.8 0.0021 18.4 0.2 5.9 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-Di19 PF05605.12 KXS96555.1 - 0.011 16.0 11.4 0.064 13.6 0.0 4.3 3 1 1 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding DUF4729 PF15866.5 KXS96555.1 - 0.015 14.6 6.6 0.51 9.6 0.1 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4729) zf-RAG1 PF10426.9 KXS96555.1 - 0.076 13.2 17.2 0.17 12.1 0.0 5.5 5 0 0 5 5 5 0 Recombination-activating protein 1 zinc-finger domain zf-C2H2_4 PF13894.6 KXS96555.1 - 0.082 13.8 24.8 1.1 10.2 0.2 6.5 6 1 0 6 6 6 0 C2H2-type zinc finger zf_C2HC_14 PF18574.1 KXS96555.1 - 0.082 12.7 3.5 6.8 6.6 0.0 3.5 3 0 0 3 3 3 0 C2HC Zing finger domain zf-H2C2_2 PF13465.6 KXS96555.1 - 0.14 12.6 0.2 0.14 12.6 0.2 5.2 7 0 0 7 7 6 0 Zinc-finger double domain zf-C2H2_aberr PF17017.5 KXS96555.1 - 0.21 11.7 5.8 0.58 10.3 0.4 3.2 3 1 0 3 3 3 0 Aberrant zinc-finger zf-Nse PF11789.8 KXS96555.1 - 0.22 11.3 4.2 23 4.9 0.1 4.4 4 0 0 4 4 4 0 Zinc-finger of the MIZ type in Nse subunit zf-TRAF_2 PF15965.5 KXS96555.1 - 0.22 12.0 2.9 0.39 11.2 0.4 2.5 2 0 0 2 2 2 0 TRAF-like zinc-finger IBR PF01485.21 KXS96555.1 - 0.24 11.7 12.9 0.83 9.9 0.4 4.6 2 2 1 3 3 3 0 IBR domain, a half RING-finger domain Acetyltransf_10 PF13673.7 KXS96556.1 - 1.2e-07 31.7 0.0 0.015 15.3 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.6 KXS96556.1 - 0.00019 22.1 0.0 0.00034 21.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXS96556.1 - 0.00036 20.7 0.0 0.00068 19.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXS96556.1 - 0.00062 20.1 0.0 0.0011 19.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXS96556.1 - 0.078 13.1 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF952 PF06108.12 KXS96559.1 - 1.3e-16 60.3 0.0 1.6e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF952) Tom22 PF04281.13 KXS96560.1 - 1.7e-52 176.9 1.7 1.9e-52 176.7 1.7 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Croc_4 PF17691.1 KXS96560.1 - 0.0089 16.1 0.0 0.013 15.6 0.0 1.2 1 0 0 1 1 1 1 Contingent replication of cDNA 4 GATA PF00320.27 KXS96561.1 - 4e-05 23.1 1.1 0.01 15.4 0.2 2.5 2 0 0 2 2 2 2 GATA zinc finger DUF2207 PF09972.9 KXS96562.1 - 0.027 13.2 1.3 2 7.1 0.2 3.0 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) BLM10_N PF16547.5 KXS96562.1 - 0.19 12.0 0.8 1.7 9.0 0.0 2.4 2 0 0 2 2 2 0 Proteasome-substrate-size regulator, N-terminal His_Phos_1 PF00300.22 KXS96562.1 - 0.99 9.1 5.3 2.1 8.0 5.3 1.5 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) NEMP PF10225.9 KXS96562.1 - 1.4 8.5 8.5 0.19 11.4 3.6 2.0 2 0 0 2 2 2 0 NEMP family DUF2207 PF09972.9 KXS96563.1 - 0.027 13.2 1.3 2 7.1 0.2 3.0 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) BLM10_N PF16547.5 KXS96563.1 - 0.19 12.0 0.8 1.7 9.0 0.0 2.4 2 0 0 2 2 2 0 Proteasome-substrate-size regulator, N-terminal His_Phos_1 PF00300.22 KXS96563.1 - 0.99 9.1 5.3 2.1 8.0 5.3 1.5 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) NEMP PF10225.9 KXS96563.1 - 1.4 8.5 8.5 0.19 11.4 3.6 2.0 2 0 0 2 2 2 0 NEMP family Aminotran_3 PF00202.21 KXS96564.1 - 2e-121 405.4 0.0 2.5e-121 405.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Iso_dh PF00180.20 KXS96566.1 - 1.8e-114 382.5 0.0 2.5e-114 382.0 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Dabb PF07876.12 KXS96567.1 - 1.4e-13 51.3 0.0 3.5e-12 46.8 0.0 2.0 1 1 0 1 1 1 1 Stress responsive A/B Barrel Domain LSM PF01423.22 KXS96568.1 - 3.2e-17 62.0 0.1 4.7e-17 61.4 0.1 1.2 1 0 0 1 1 1 1 LSM domain Mac PF12464.8 KXS96568.1 - 0.022 15.0 0.2 0.044 14.0 0.2 1.5 1 0 0 1 1 1 0 Maltose acetyltransferase LSM PF01423.22 KXS96569.1 - 3.2e-17 62.0 0.1 4.7e-17 61.4 0.1 1.2 1 0 0 1 1 1 1 LSM domain Mac PF12464.8 KXS96569.1 - 0.022 15.0 0.2 0.044 14.0 0.2 1.5 1 0 0 1 1 1 0 Maltose acetyltransferase SGL PF08450.12 KXS96570.1 - 1.2e-28 100.4 0.2 1.7e-28 99.9 0.2 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Lactonase PF10282.9 KXS96570.1 - 0.00089 18.6 0.1 0.0033 16.7 0.0 1.8 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller CHU_C PF13585.6 KXS96570.1 - 0.0048 16.9 0.0 0.0096 16.0 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of CHU protein family NHL PF01436.21 KXS96570.1 - 0.011 15.7 0.1 1.6 8.9 0.0 3.4 3 0 0 3 3 3 0 NHL repeat Arylesterase PF01731.20 KXS96570.1 - 0.017 15.3 0.0 0.043 14.0 0.0 1.7 1 0 0 1 1 1 0 Arylesterase His_Phos_1 PF00300.22 KXS96571.1 - 6.4e-19 68.4 0.0 1.4e-18 67.3 0.0 1.5 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Alpha-amylase_C PF02806.18 KXS96573.1 - 1.4e-26 92.8 0.1 2.7e-26 91.8 0.1 1.5 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 KXS96573.1 - 1.6e-15 57.2 0.0 3.9e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 KXS96573.1 - 2.5e-14 53.6 0.3 3.8e-11 43.1 0.4 2.3 1 1 1 2 2 2 2 Alpha amylase, catalytic domain AbiEi_3 PF11459.8 KXS96573.1 - 0.19 11.4 0.1 0.4 10.4 0.1 1.4 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin, Type IV TA system Beta-lactamase PF00144.24 KXS96574.1 - 0.0013 18.0 0.0 0.0014 18.0 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase Pro_isomerase PF00160.21 KXS96575.1 - 3.2e-48 164.0 0.1 8.9e-48 162.5 0.0 1.8 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.12 KXS96575.1 - 9.3e-05 21.9 1.0 9.3e-05 21.9 1.0 2.2 2 1 0 2 2 2 1 Rtf2 RING-finger U-box PF04564.15 KXS96575.1 - 0.00021 21.4 0.1 0.0017 18.5 0.0 2.5 2 1 1 3 3 3 1 U-box domain zf-NOSIP PF15906.5 KXS96575.1 - 0.0008 19.5 0.0 0.003 17.6 0.0 2.0 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein MGC-24 PF05283.11 KXS96575.1 - 2.3 8.7 6.1 4.2 7.8 6.1 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Ank_3 PF13606.6 KXS96576.1 - 2.2e-13 49.1 0.3 3e-05 24.1 0.0 5.7 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 KXS96576.1 - 2.3e-13 50.4 0.0 0.0014 19.2 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXS96576.1 - 3.8e-12 46.6 0.0 7.7e-05 23.2 0.0 3.5 2 2 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXS96576.1 - 6.2e-10 39.1 1.1 0.0031 17.9 0.1 4.8 4 1 1 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 KXS96576.1 - 1e-07 32.1 0.1 0.019 15.3 0.0 3.0 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Glyco_transf_25 PF01755.17 KXS96577.1 - 1.4e-06 28.3 0.0 2.4e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase family 25 (LPS biosynthesis protein) CbtB PF09489.10 KXS96577.1 - 0.22 11.6 0.7 24 5.1 0.1 2.4 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) Clr5 PF14420.6 KXS96579.1 - 0.00017 21.8 3.1 0.0041 17.3 0.2 2.7 2 1 1 3 3 3 2 Clr5 domain HTH_21 PF13276.6 KXS96579.1 - 0.065 13.4 2.0 9.1 6.5 0.2 2.9 2 1 0 2 2 2 0 HTH-like domain LEM PF03020.15 KXS96579.1 - 0.24 11.0 0.9 0.59 9.7 0.0 2.2 2 0 0 2 2 2 0 LEM domain SPESP1 PF15754.5 KXS96580.1 - 0.32 10.1 3.9 0.58 9.3 3.8 1.5 1 1 0 1 1 1 0 Sperm equatorial segment protein 1 Apt1 PF10351.9 KXS96580.1 - 0.47 9.2 3.3 0.5 9.2 3.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CDC45 PF02724.14 KXS96580.1 - 1.4 7.1 7.5 1.8 6.8 7.5 1.1 1 0 0 1 1 1 0 CDC45-like protein PQ-loop PF04193.14 KXS96581.1 - 1.1e-39 134.0 5.9 2.8e-20 71.8 0.1 2.5 2 0 0 2 2 2 2 PQ loop repeat TMEM132D_C PF15706.5 KXS96581.1 - 0.01 15.6 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term ER_lumen_recept PF00810.18 KXS96581.1 - 0.094 13.5 1.0 4.1 8.2 0.0 2.7 2 1 1 3 3 3 0 ER lumen protein retaining receptor zf-TRM13_CCCH PF11722.8 KXS96581.1 - 0.18 11.6 0.3 0.32 10.8 0.3 1.4 1 0 0 1 1 1 0 CCCH zinc finger in TRM13 protein NPR1_like_C PF12313.8 KXS96582.1 - 0.00091 18.8 0.0 0.05 13.1 0.1 2.2 2 0 0 2 2 2 2 NPR1/NIM1 like defence protein C terminal Peptidase_S28 PF05577.12 KXS96584.1 - 1.8e-46 158.9 5.0 3.2e-46 158.0 5.0 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase S28 FA_hydroxylase PF04116.13 KXS96585.1 - 8.2e-21 74.7 9.3 8.2e-21 74.7 9.3 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF412 PF04217.13 KXS96585.1 - 0.022 14.6 0.1 0.063 13.2 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF412 DNA_primase_lrg PF04104.14 KXS96587.1 - 0.022 14.2 1.2 0.025 14.0 1.2 1.1 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase, large subunit DUF3685 PF12452.8 KXS96587.1 - 0.048 13.4 0.3 0.048 13.4 0.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3685) MARVEL PF01284.23 KXS96588.1 - 6.1e-17 62.0 8.1 7.8e-17 61.7 8.1 1.1 1 0 0 1 1 1 1 Membrane-associating domain AUX_IAA PF02309.16 KXS96589.1 - 1.4 8.7 8.4 0.27 11.1 4.9 1.4 1 1 0 1 1 1 0 AUX/IAA family Hydin_ADK PF17213.3 KXS96589.1 - 1.7 8.9 8.7 2 8.7 8.7 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain DUF3716 PF12511.8 KXS96590.1 - 8.3e-05 22.5 8.1 0.00018 21.4 8.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) DUF3716 PF12511.8 KXS96591.1 - 1.9e-08 34.2 4.0 3.5e-08 33.4 4.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) OPT PF03169.15 KXS96592.1 - 4.3e-62 210.6 13.1 5.2e-62 210.4 13.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein SNARE_assoc PF09335.11 KXS96592.1 - 0.0027 18.2 2.0 0.0027 18.2 2.0 2.6 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF1275 PF06912.11 KXS96592.1 - 0.073 13.0 6.7 0.023 14.6 2.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1275) SLATT_1 PF18181.1 KXS96592.1 - 0.13 12.2 1.2 0.15 12.0 0.1 1.7 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 DUF4231 PF14015.6 KXS96592.1 - 0.41 11.2 1.7 0.88 10.1 0.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) DUF3093 PF11292.8 KXS96592.1 - 0.66 10.2 4.5 1.7 8.9 4.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3093) DUF4064 PF13273.6 KXS96592.1 - 1.3 9.3 8.9 0.25 11.6 0.2 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF4064) OPT PF03169.15 KXS96593.1 - 1.3e-50 172.7 21.6 1.4e-50 172.6 21.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein OPT PF03169.15 KXS96594.1 - 1.3e-50 172.7 21.6 1.4e-50 172.6 21.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Nucleo_P87 PF07267.11 KXS96595.1 - 5.5 5.7 12.5 6.7 5.4 12.5 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Cu-oxidase_3 PF07732.15 KXS96596.1 - 2.8e-38 130.6 0.7 2.8e-38 130.6 0.7 2.3 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 KXS96596.1 - 2.6e-27 95.9 0.2 7.9e-26 91.1 0.0 2.8 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KXS96596.1 - 2.4e-24 85.6 6.1 7.9e-23 80.7 1.7 3.3 3 1 0 3 3 3 2 Multicopper oxidase AhpC-TSA_2 PF13911.6 KXS96597.1 - 8.6e-17 61.3 0.0 3.6e-16 59.3 0.0 1.9 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 KXS96597.1 - 0.0055 16.6 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KXS96597.1 - 0.13 11.9 0.0 0.42 10.3 0.0 1.8 1 1 0 1 1 1 0 Redoxin DZR PF12773.7 KXS96597.1 - 0.16 12.0 0.8 0.86 9.7 0.9 2.0 1 1 1 2 2 2 0 Double zinc ribbon T2SSM PF04612.12 KXS96598.1 - 0.034 14.2 0.0 0.044 13.8 0.0 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M PMEI PF04043.15 KXS96598.1 - 0.035 14.4 0.0 0.037 14.4 0.0 1.1 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor DpnI_C PF17726.1 KXS96598.1 - 0.12 12.5 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 Dam-replacing HTH domain DivIC PF04977.15 KXS96599.1 - 0.00093 18.9 4.5 0.0017 18.1 4.5 1.4 1 0 0 1 1 1 1 Septum formation initiator BMFP PF04380.13 KXS96599.1 - 0.0019 18.7 0.9 0.0035 17.8 0.9 1.5 1 0 0 1 1 1 1 Membrane fusogenic activity Oberon_cc PF16312.5 KXS96599.1 - 0.0079 16.1 0.8 0.016 15.2 0.3 1.6 2 0 0 2 2 2 1 Coiled-coil region of Oberon Tropomyosin_1 PF12718.7 KXS96599.1 - 0.015 15.4 6.0 0.022 14.9 6.0 1.2 1 0 0 1 1 1 0 Tropomyosin like Mto2_bdg PF12808.7 KXS96599.1 - 0.038 14.3 2.7 0.068 13.5 2.7 1.4 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Macoilin PF09726.9 KXS96599.1 - 0.12 10.9 3.6 0.13 10.8 3.6 1.1 1 0 0 1 1 1 0 Macoilin family bZIP_2 PF07716.15 KXS96599.1 - 0.16 12.0 4.7 0.28 11.3 4.7 1.4 1 0 0 1 1 1 0 Basic region leucine zipper Halogen_Hydrol PF10112.9 KXS96599.1 - 0.3 11.1 2.7 0.37 10.8 1.2 1.7 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF4381 PF14316.6 KXS96600.1 - 0.1 12.9 0.6 0.18 12.0 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) CFEM PF05730.11 KXS96600.1 - 1.8 8.7 14.4 5.3 7.2 14.3 1.9 1 1 1 2 2 2 0 CFEM domain TIL PF01826.17 KXS96600.1 - 7.1 7.0 8.5 7.2 7.0 1.5 2.5 1 1 1 2 2 2 0 Trypsin Inhibitor like cysteine rich domain RPN7 PF10602.9 KXS96601.1 - 6.5e-26 91.1 0.3 9.4e-15 54.7 0.0 3.3 3 1 0 3 3 3 2 26S proteasome subunit RPN7 PCI PF01399.27 KXS96601.1 - 2.2e-10 41.0 0.0 6.1e-10 39.5 0.0 1.8 1 0 0 1 1 1 1 PCI domain DSBA PF01323.20 KXS96601.1 - 0.048 13.4 0.3 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 DSBA-like thioredoxin domain SOG2 PF10428.9 KXS96602.1 - 7.8 5.6 18.3 8.2 5.5 18.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Response_reg PF00072.24 KXS96603.1 - 1.1e-22 80.2 0.1 3e-22 78.9 0.1 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 KXS96603.1 - 1.9e-21 76.7 0.0 4.1e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_4 PF08448.10 KXS96603.1 - 1.1e-06 28.9 0.1 0.019 15.2 0.0 3.1 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 KXS96603.1 - 6.4e-05 22.9 0.0 0.00023 21.1 0.0 2.0 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 KXS96603.1 - 0.0013 18.7 0.0 0.0037 17.2 0.0 1.8 1 0 0 1 1 1 1 PAS fold HisKA PF00512.25 KXS96603.1 - 0.0019 18.2 0.3 0.0019 18.2 0.3 2.7 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF_3 PF13492.6 KXS96603.1 - 0.044 14.1 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 GAF domain HATPase_c_3 PF13589.6 KXS96603.1 - 0.045 13.6 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_7 PF12860.7 KXS96603.1 - 0.12 12.5 0.0 2 8.6 0.0 3.0 3 0 0 3 3 3 0 PAS fold SH3_9 PF14604.6 KXS96607.1 - 2.1e-09 37.1 0.0 3.7e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS96607.1 - 1.3e-06 27.9 0.0 2.1e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KXS96607.1 - 2.9e-05 23.7 0.0 5.8e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Abhydrolase_6 PF12697.7 KXS96608.1 - 5.1e-08 33.8 0.2 7.3e-08 33.3 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXS96608.1 - 1.2e-06 28.0 0.0 2.2e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXS96608.1 - 1.3e-06 28.3 0.0 2.4e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Herpes_BTRF1 PF04682.12 KXS96608.1 - 0.16 11.3 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus BTRF1 protein conserved region Arylsulfotran_2 PF14269.6 KXS96609.1 - 2.1e-33 116.0 0.7 3.1e-33 115.4 0.7 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KXS96609.1 - 4e-18 65.5 0.9 1.4e-17 63.7 0.9 1.7 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Aldo_ket_red PF00248.21 KXS96610.1 - 1.2e-54 185.5 0.0 1.4e-54 185.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Tyrosinase PF00264.20 KXS96612.1 - 1.4e-49 169.3 0.3 1.4e-49 169.3 0.3 1.6 2 0 0 2 2 2 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 KXS96612.1 - 2.5e-23 83.0 0.0 4.8e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 Tyosinase C-terminal domain Beta-lactamase PF00144.24 KXS96613.1 - 5.2e-23 81.8 0.0 1.3e-22 80.6 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase Fungal_trans PF04082.18 KXS96613.1 - 1.9e-10 40.3 0.1 3.3e-10 39.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS96613.1 - 2.1e-07 30.9 8.0 3.5e-07 30.2 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GH131_N PF18271.1 KXS96615.1 - 1.4e-63 215.0 1.5 1.6e-63 214.8 1.5 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain Ribonucleas_3_2 PF11469.8 KXS96616.1 - 0.019 15.4 0.0 0.022 15.1 0.0 1.1 1 0 0 1 1 1 0 Ribonuclease III IBR PF01485.21 KXS96618.1 - 1.4e-08 34.8 39.7 1.3e-05 25.4 14.4 3.1 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain GatB_N PF02934.15 KXS96619.1 - 7.3e-94 314.2 0.0 1e-93 313.7 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 KXS96619.1 - 1.8e-11 44.2 0.1 4e-11 43.0 0.1 1.5 1 0 0 1 1 1 1 GatB domain Nbs1_C PF08599.10 KXS96619.1 - 0.0026 17.9 0.2 2.5 8.3 0.1 2.7 2 0 0 2 2 2 2 DNA damage repair protein Nbs1 HTH_ParB PF17762.1 KXS96619.1 - 0.02 14.7 0.7 0.64 9.9 0.0 2.8 3 0 0 3 3 3 0 HTH domain found in ParB protein DUF2157 PF09925.9 KXS96619.1 - 0.052 13.3 1.8 0.11 12.3 1.8 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) Pkinase PF00069.25 KXS96620.1 - 3.7e-09 36.3 0.0 5.1e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KXS96620.1 - 3.8e-05 23.1 0.0 6.1e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXS96620.1 - 0.00022 21.2 0.6 0.00029 20.8 0.6 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KXS96620.1 - 0.0049 16.2 0.0 0.0085 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS96620.1 - 0.019 14.3 0.0 0.027 13.8 0.0 1.1 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 KXS96620.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 KXS96620.1 - 0.14 11.8 0.1 0.19 11.3 0.1 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Rep_fac-A_C PF08646.10 KXS96621.1 - 1.8e-53 180.2 9.7 6.7e-52 175.1 7.2 2.6 2 0 0 2 2 2 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 KXS96621.1 - 7.1e-36 122.1 0.6 2e-35 120.6 0.1 2.0 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 KXS96621.1 - 3.3e-22 78.4 0.0 7.3e-22 77.3 0.0 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 KXS96621.1 - 3e-13 49.5 0.0 1e-08 35.0 0.0 4.3 4 0 0 4 4 4 1 OB-fold nucleic acid binding domain DUF4503 PF14951.6 KXS96621.1 - 0.03 12.8 0.1 0.067 11.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) DUF5521 PF17659.1 KXS96621.1 - 0.03 12.2 0.0 0.23 9.2 0.0 2.0 1 1 0 1 1 1 0 Family of unknown function (DUF5521) DUF4539 PF15072.6 KXS96621.1 - 0.042 13.9 0.0 31 4.7 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4539) CDC24_OB3 PF17244.2 KXS96621.1 - 0.061 13.0 0.2 1.2 8.8 0.0 2.7 3 0 0 3 3 3 0 Cell division control protein 24, OB domain 3 Aspzincin_M35 PF14521.6 KXS96622.1 - 0.0013 19.3 0.1 0.0055 17.2 0.0 2.1 2 1 0 2 2 2 1 Lysine-specific metallo-endopeptidase Aspzincin_M35 PF14521.6 KXS96623.1 - 0.0013 19.3 0.1 0.0055 17.2 0.0 2.1 2 1 0 2 2 2 1 Lysine-specific metallo-endopeptidase Aspzincin_M35 PF14521.6 KXS96624.1 - 0.0013 19.3 0.1 0.0055 17.2 0.0 2.1 2 1 0 2 2 2 1 Lysine-specific metallo-endopeptidase Peroxidase_2 PF01328.17 KXS96625.1 - 1.8e-45 155.7 0.0 2.6e-45 155.3 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 Kinesin PF00225.23 KXS96626.1 - 7.4e-85 284.8 0.4 1.1e-84 284.3 0.4 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXS96626.1 - 1.5e-22 80.1 0.0 3.2e-22 79.1 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding HHH PF00633.23 KXS96626.1 - 4.6e-05 23.1 0.3 0.011 15.6 0.0 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_3 PF12836.7 KXS96626.1 - 0.00031 20.9 0.0 0.00071 19.8 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 KXS96626.1 - 0.001 19.6 0.8 0.3 11.7 0.2 2.8 1 1 1 2 2 2 2 Helix-hairpin-helix domain PBP1_TM PF14812.6 KXS96626.1 - 0.96 9.9 4.8 3.1 8.2 4.8 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Alpha-amylase PF00128.24 KXS96627.1 - 9.1e-17 61.6 4.3 1.2e-16 61.2 4.3 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Caud_tail_N PF16838.5 KXS96627.1 - 0.065 13.7 0.4 0.13 12.7 0.4 1.5 1 0 0 1 1 1 0 Caudoviral major tail protein N-terminus UTP15_C PF09384.10 KXS96635.1 - 7.9e-41 139.2 0.0 1.3e-40 138.4 0.0 1.4 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 KXS96635.1 - 5.6e-12 46.0 11.5 0.011 16.6 0.7 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS96635.1 - 0.012 15.9 0.3 3.7 7.9 0.1 3.4 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain HLH PF00010.26 KXS96636.1 - 5.8e-06 26.2 0.0 9.7e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DSBA PF01323.20 KXS96636.1 - 0.033 14.0 0.3 0.043 13.6 0.3 1.3 1 0 0 1 1 1 0 DSBA-like thioredoxin domain DUF1850 PF08905.11 KXS96636.1 - 0.11 12.8 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1850) Glyco_hydro_31 PF01055.26 KXS96637.1 - 1.8e-150 502.0 7.5 2.3e-150 501.6 7.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KXS96637.1 - 4.2e-31 107.5 0.0 7.5e-31 106.7 0.0 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KXS96637.1 - 0.0028 17.9 1.4 0.022 15.1 1.4 2.6 1 1 0 1 1 1 1 Galactose mutarotase-like DUF4416 PF14385.6 KXS96637.1 - 0.0063 16.4 0.5 4 7.3 0.2 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4416) GHL15 PF14885.6 KXS96637.1 - 0.11 12.4 1.4 0.21 11.5 1.4 1.4 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 15 Glyco_hydro_1 PF00232.18 KXS96638.1 - 1.3e-54 185.4 0.0 1.4e-54 185.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_1 PF00232.18 KXS96639.1 - 8.5e-116 387.0 0.0 9.5e-116 386.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_1 PF00232.18 KXS96640.1 - 6.8e-160 532.4 2.0 8.4e-159 528.8 2.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 DUF2095 PF09868.9 KXS96640.1 - 0.01 15.8 0.1 0.033 14.2 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2095) AID PF18767.1 KXS96640.1 - 0.17 11.9 0.0 0.34 11.0 0.0 1.4 1 0 0 1 1 1 0 Activation induced deaminase eIF-5_eIF-2B PF01873.17 KXS96643.1 - 5.2e-42 142.4 0.2 8.5e-42 141.7 0.2 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 KXS96643.1 - 0.11 12.1 0.8 0.21 11.1 0.8 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding CDC45 PF02724.14 KXS96643.1 - 0.51 8.6 6.9 0.52 8.5 6.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Cnd2 PF05786.14 KXS96643.1 - 0.79 8.3 15.2 1.2 7.7 15.2 1.3 1 0 0 1 1 1 0 Condensin complex subunit 2 RR_TM4-6 PF06459.12 KXS96643.1 - 1 9.1 17.4 1.5 8.6 17.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Arc_trans_TRASH PF08394.10 KXS96643.1 - 1.7 9.1 7.2 1.2 9.6 0.3 2.6 1 1 1 2 2 2 0 Archaeal TRASH domain zf-HYPF PF07503.12 KXS96643.1 - 2.6 7.9 6.1 25 4.7 4.0 2.7 2 1 1 3 3 3 0 HypF finger TFIIF_alpha PF05793.12 KXS96643.1 - 3.2 6.2 25.2 4.4 5.8 25.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Abhydrolase_6 PF12697.7 KXS96645.1 - 2.3e-07 31.7 0.1 3.5e-07 31.0 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KXS96645.1 - 0.00015 21.3 0.0 0.25 10.8 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KXS96645.1 - 0.004 16.5 0.1 0.13 11.5 0.1 2.5 2 1 1 3 3 3 1 Serine aminopeptidase, S33 PhoPQ_related PF10142.9 KXS96645.1 - 0.015 14.0 0.0 0.031 13.0 0.0 1.6 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Spo0A_C PF08769.11 KXS96647.1 - 0.034 14.2 0.6 0.13 12.4 0.1 2.0 1 1 1 2 2 2 0 Sporulation initiation factor Spo0A C terminal DinI PF06183.13 KXS96647.1 - 0.052 13.9 0.3 0.089 13.1 0.3 1.4 1 0 0 1 1 1 0 DinI-like family Cerato-platanin PF07249.12 KXS96648.1 - 1.2e-51 173.8 3.1 1.5e-51 173.5 3.1 1.1 1 0 0 1 1 1 1 Cerato-platanin Glyco_hydro_15 PF00723.21 KXS96649.1 - 2.3e-61 208.0 0.6 2.9e-61 207.6 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 bZIP_1 PF00170.21 KXS96652.1 - 0.00037 20.5 8.5 0.0043 17.1 8.1 2.1 1 1 1 2 2 2 1 bZIP transcription factor CCDC106 PF15794.5 KXS96652.1 - 0.015 15.1 2.1 0.015 15.1 2.1 2.2 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 106 BST2 PF16716.5 KXS96652.1 - 0.14 12.7 4.1 0.39 11.3 3.9 1.7 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 YabA PF06156.13 KXS96652.1 - 0.2 12.3 1.4 0.34 11.6 1.4 1.3 1 0 0 1 1 1 0 Initiation control protein YabA bZIP_2 PF07716.15 KXS96652.1 - 0.3 11.2 10.6 3.1 8.0 4.3 2.3 2 0 0 2 2 2 0 Basic region leucine zipper Tox-ODYAM1 PF15642.6 KXS96652.1 - 0.42 9.5 2.7 0.57 9.1 2.7 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus HAUS6_N PF14661.6 KXS96652.1 - 8.9 5.8 7.4 13 5.3 7.4 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Membr_traf_MHD PF10540.9 KXS96653.1 - 8.4e-20 71.5 1.2 7.7e-17 61.8 1.2 2.8 1 1 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 KXS96653.1 - 9.7e-16 57.9 0.0 2.2e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.11 KXS96653.1 - 0.00025 19.8 1.1 0.00042 19.0 0.3 1.8 2 0 0 2 2 2 1 Plant family of unknown function (DUF810) Nitroreductase PF00881.24 KXS96653.1 - 0.1 12.6 5.7 2.8 8.0 0.6 3.1 2 1 0 3 3 3 0 Nitroreductase family Collagen PF01391.18 KXS96654.1 - 1.3e-10 40.9 39.5 1.1e-06 28.3 20.3 2.4 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) DIOX_N PF14226.6 KXS96655.1 - 3.8e-36 124.4 0.0 4.3e-34 117.8 0.0 2.3 2 0 0 2 2 2 2 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXS96655.1 - 2.1e-09 37.8 0.0 8.6e-07 29.4 0.0 2.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Collagen PF01391.18 KXS96656.1 - 2.9e-18 65.4 59.2 5.3e-09 35.7 20.2 3.3 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) WSC PF01822.19 KXS96656.1 - 0.00012 22.2 2.2 0.00019 21.6 2.2 1.3 1 0 0 1 1 1 1 WSC domain DUF1479 PF07350.12 KXS96657.1 - 4.3e-167 556.1 0.0 5.2e-167 555.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Glyco_hydro_88 PF07470.13 KXS96661.1 - 2.2e-90 303.2 1.5 2.5e-90 303.1 1.5 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 KXS96661.1 - 0.00031 19.4 0.2 0.00042 18.9 0.2 1.2 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 MFS_1 PF07690.16 KXS96663.1 - 7.9e-36 123.7 28.7 1.1e-35 123.3 28.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily CheZ PF04344.13 KXS96663.1 - 0.004 17.1 0.2 0.0078 16.1 0.2 1.4 1 0 0 1 1 1 1 Chemotaxis phosphatase, CheZ Mob_Pre PF01076.19 KXS96663.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Plasmid recombination enzyme DUF155 PF02582.14 KXS96664.1 - 3.5e-50 170.5 0.0 5.1e-50 170.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF498 PF04430.14 KXS96664.1 - 0.0034 17.4 0.0 0.5 10.5 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF498/DUF598) Cupin_1 PF00190.22 KXS96664.1 - 0.056 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Cupin Ank_4 PF13637.6 KXS96665.1 - 9.3e-32 109.0 8.5 0.00018 22.0 0.0 10.0 6 4 3 10 10 10 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXS96665.1 - 3.5e-30 104.4 6.1 5e-08 33.4 0.0 6.5 4 2 3 7 7 7 5 Ankyrin repeats (3 copies) Ank PF00023.30 KXS96665.1 - 8e-24 83.0 18.2 0.0039 17.6 0.0 11.0 11 1 0 11 11 11 7 Ankyrin repeat Ank_5 PF13857.6 KXS96665.1 - 1.2e-20 73.3 15.9 0.0042 17.4 0.0 9.0 7 1 2 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS96665.1 - 1.7e-15 55.5 13.3 0.075 13.6 0.0 12.2 12 1 0 12 12 12 4 Ankyrin repeat NACHT PF05729.12 KXS96665.1 - 8.7e-09 35.5 0.0 2.9e-08 33.8 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KXS96665.1 - 0.00012 22.5 0.0 0.00066 20.1 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain ADH_zinc_N PF00107.26 KXS96666.1 - 3e-12 46.7 2.5 4.9e-12 46.0 2.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXS96666.1 - 6.9e-08 32.3 0.0 3.6e-07 30.0 0.0 2.3 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KXS96666.1 - 0.0079 17.2 0.1 0.017 16.2 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glyoxalase PF00903.25 KXS96667.1 - 0.0031 17.7 0.0 0.0096 16.1 0.0 1.8 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily NICE-1 PF15845.5 KXS96667.1 - 0.1 13.4 0.3 0.1 13.4 0.3 4.0 5 0 0 5 5 5 0 Cysteine-rich C-terminal 1 family Pkinase PF00069.25 KXS96668.1 - 1.1e-59 202.0 0.0 1.8e-59 201.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS96668.1 - 7.3e-42 143.4 0.0 1.1e-41 142.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS96668.1 - 1.7e-07 30.8 0.0 3.9e-05 23.1 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 KXS96668.1 - 0.029 13.7 0.0 0.057 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KXS96668.1 - 0.17 10.6 0.2 0.45 9.2 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Clathrin PF00637.20 KXS96669.1 - 1.3e-14 54.2 0.0 2.9e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Region in Clathrin and VPS Vps39_1 PF10366.9 KXS96669.1 - 0.012 15.8 0.2 0.056 13.7 0.0 2.0 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 WD40 PF00400.32 KXS96669.1 - 0.022 15.6 1.4 39 5.3 0.0 5.0 5 0 0 5 5 5 0 WD domain, G-beta repeat zf-RING_2 PF13639.6 KXS96669.1 - 0.032 14.6 1.2 0.073 13.4 1.2 1.6 1 0 0 1 1 1 0 Ring finger domain C1_1 PF00130.22 KXS96669.1 - 0.076 12.9 0.3 0.15 12.0 0.3 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_UBOX PF13445.6 KXS96669.1 - 0.12 12.4 0.1 0.32 11.0 0.1 1.7 1 0 0 1 1 1 0 RING-type zinc-finger WD40_like PF17005.5 KXS96669.1 - 0.16 11.2 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 WD40-like domain zf-RING_5 PF14634.6 KXS96669.1 - 0.17 11.8 0.8 0.43 10.6 0.8 1.6 1 0 0 1 1 1 0 zinc-RING finger domain DUF2175 PF09943.9 KXS96669.1 - 0.21 11.9 0.1 0.46 10.8 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) zf-RING_11 PF17123.5 KXS96669.1 - 0.23 11.2 3.8 0.48 10.2 3.8 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-rbx1 PF12678.7 KXS96669.1 - 0.23 11.8 1.5 0.52 10.6 1.5 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain DNA_pol_phi PF04931.13 KXS96669.1 - 9.4 4.2 7.0 14 3.6 7.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi Bacteriocin_IIc PF10439.9 KXS96670.1 - 0.056 13.6 1.4 0.056 13.6 1.4 1.8 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide DUF2070 PF09843.9 KXS96670.1 - 2.4 6.3 8.6 3.2 5.9 8.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) MFS_1 PF07690.16 KXS96672.1 - 4.6e-36 124.5 28.1 6.3e-36 124.0 28.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily fn3_3 PF14686.6 KXS96673.1 - 5.4e-23 80.6 2.9 1.3e-22 79.4 2.9 1.7 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CBM-like PF14683.6 KXS96673.1 - 1.9e-18 66.9 0.2 1.1e-17 64.4 0.0 2.3 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III CarboxypepD_reg PF13620.6 KXS96673.1 - 0.09 13.1 0.6 0.27 11.5 0.6 1.9 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain DUF2012 PF09430.10 KXS96673.1 - 0.15 12.1 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2012) GFA PF04828.14 KXS96674.1 - 3.1e-20 72.3 3.2 4.2e-20 71.9 3.2 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Yippee-Mis18 PF03226.14 KXS96674.1 - 0.27 11.5 4.6 0.39 10.9 4.6 1.2 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly SSP160 PF06933.11 KXS96677.1 - 5.7 5.0 15.5 7.6 4.6 15.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Csm1 PF12539.8 KXS96678.1 - 1.3e-33 115.5 0.0 3e-33 114.3 0.0 1.6 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 HAUS-augmin3 PF14932.6 KXS96678.1 - 0.0043 16.7 20.7 0.0043 16.7 20.7 2.2 2 1 0 2 2 2 1 HAUS augmin-like complex subunit 3 RILP PF11461.8 KXS96678.1 - 0.029 14.6 4.6 0.22 11.8 4.6 2.6 1 0 0 1 1 1 0 Rab interacting lysosomal protein DUF948 PF06103.11 KXS96678.1 - 0.11 12.7 5.3 0.24 11.7 4.2 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF5094 PF17015.5 KXS96678.1 - 0.33 11.0 0.0 0.33 11.0 0.0 4.3 3 1 0 3 3 3 0 Domain of unknown function (DUF5094) CENP-F_leu_zip PF10473.9 KXS96678.1 - 1.2 9.2 24.5 9.3 6.3 24.5 2.3 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prominin PF05478.11 KXS96678.1 - 3.4 5.5 16.0 4.9 5.0 16.0 1.2 1 0 0 1 1 1 0 Prominin JIP_LZII PF16471.5 KXS96678.1 - 4.9 7.4 14.6 1.5 9.0 10.2 2.4 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II Aconitase PF00330.20 KXS96681.1 - 7.2e-162 539.6 0.0 8.9e-162 539.3 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KXS96681.1 - 1.7e-41 141.6 0.0 4.7e-41 140.2 0.0 1.8 2 0 0 2 2 2 1 Aconitase C-terminal domain Aconitase PF00330.20 KXS96682.1 - 7.2e-162 539.6 0.0 8.9e-162 539.3 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KXS96682.1 - 1.7e-41 141.6 0.0 4.7e-41 140.2 0.0 1.8 2 0 0 2 2 2 1 Aconitase C-terminal domain Fungal_trans PF04082.18 KXS96683.1 - 1.9e-62 210.7 0.0 3e-62 210.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KXS96683.1 - 7.7e-05 22.9 12.2 8.7e-05 22.8 0.9 3.0 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXS96683.1 - 0.0073 16.7 9.6 0.32 11.5 4.2 3.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXS96683.1 - 0.06 14.2 0.7 0.06 14.2 0.7 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger WD40 PF00400.32 KXS96684.1 - 0.031 15.2 2.0 11 7.1 0.6 3.7 4 0 0 4 4 4 0 WD domain, G-beta repeat HD_3 PF13023.6 KXS96685.1 - 2.8e-51 173.7 0.2 3.8e-51 173.3 0.2 1.2 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 KXS96685.1 - 3.3e-13 49.8 0.1 6.3e-13 48.9 0.1 1.5 2 0 0 2 2 2 1 HD containing hydrolase-like enzyme SUIM_assoc PF16619.5 KXS96685.1 - 0.12 12.4 0.2 0.12 12.4 0.2 1.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF4242 PF14026.6 KXS96686.1 - 0.012 15.8 1.1 0.025 14.8 0.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4242) Pyr_redox_2 PF07992.14 KXS96687.1 - 1.6e-47 162.2 0.6 1.9e-47 161.9 0.6 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXS96687.1 - 7.7e-21 74.6 1.2 1e-17 64.3 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXS96687.1 - 6.2e-15 55.5 0.1 4.4e-13 49.6 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXS96687.1 - 2.4e-06 27.0 0.1 0.00045 19.5 0.0 2.5 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 KXS96687.1 - 5.9e-06 25.6 0.2 0.0075 15.4 0.1 3.6 4 0 0 4 4 4 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KXS96687.1 - 2.1e-05 24.1 0.3 7.9e-05 22.2 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 KXS96687.1 - 0.0013 17.9 0.0 0.047 12.8 0.0 2.7 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 KXS96687.1 - 0.0024 16.6 0.2 0.075 11.7 0.1 2.9 3 0 0 3 3 3 1 HI0933-like protein DAO PF01266.24 KXS96687.1 - 0.0027 17.3 0.2 4.9 6.6 0.4 3.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXS96687.1 - 0.011 15.9 0.1 0.098 12.9 0.0 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXS96687.1 - 0.019 14.1 8.6 0.064 12.3 1.4 3.2 2 1 0 3 3 3 0 FAD binding domain NAD_binding_7 PF13241.6 KXS96687.1 - 0.083 13.3 0.2 1.1 9.8 0.0 2.5 2 1 0 2 2 2 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 KXS96687.1 - 0.14 12.3 0.1 10 6.2 0.0 3.3 4 0 0 4 4 4 0 Shikimate / quinate 5-dehydrogenase Trp_halogenase PF04820.14 KXS96687.1 - 0.15 10.8 0.2 2.1 7.1 0.1 2.5 3 0 0 3 3 3 0 Tryptophan halogenase Lzipper-MIP1 PF14389.6 KXS96688.1 - 0.061 13.6 0.0 0.19 12.1 0.0 1.8 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 PI3K_P85_iSH2 PF16454.5 KXS96688.1 - 0.11 12.1 0.0 0.49 10.0 0.0 1.8 1 1 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain LexA_DNA_bind PF01726.16 KXS96688.1 - 0.17 11.7 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 LexA DNA binding domain Peptidase_M28 PF04389.17 KXS96689.1 - 5.8e-31 107.7 0.0 9.2e-31 107.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KXS96689.1 - 3.7e-07 30.1 0.1 6.2e-07 29.3 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 KXS96689.1 - 0.01 14.8 0.2 2.7 6.9 0.1 2.2 1 1 1 2 2 2 0 M42 glutamyl aminopeptidase Sugar_tr PF00083.24 KXS96690.1 - 1.4e-77 261.5 23.6 1.5e-77 261.4 23.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS96690.1 - 2.6e-17 62.8 42.4 2.5e-11 43.1 15.7 2.7 1 1 1 3 3 3 2 Major Facilitator Superfamily MFS_5 PF05631.14 KXS96690.1 - 0.29 10.0 7.5 0.22 10.4 2.0 2.1 2 0 0 2 2 2 0 Sugar-tranasporters, 12 TM MFS_1_like PF12832.7 KXS96690.1 - 1.8 7.3 14.9 0.043 12.7 4.1 2.6 2 1 0 3 3 3 0 MFS_1 like family KRE9 PF05390.11 KXS96691.1 - 5.1e-16 59.3 9.0 5.1e-16 59.3 9.0 2.2 3 0 0 3 3 3 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.9 KXS96691.1 - 3.4e-10 40.5 0.6 3.4e-10 40.5 0.6 1.9 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family HAUS6_N PF14661.6 KXS96692.1 - 6.5e-41 140.4 0.2 6.5e-41 140.4 0.2 1.7 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 6 N-terminus Ribosomal_S21 PF01165.20 KXS96692.1 - 0.14 11.9 3.4 0.33 10.7 0.5 2.9 2 1 0 2 2 2 0 Ribosomal protein S21 dCMP_cyt_deam_1 PF00383.23 KXS96693.1 - 2.1e-21 75.7 0.1 2.6e-21 75.4 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KXS96693.1 - 1.5e-17 63.6 0.0 2e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 KXS96693.1 - 0.0094 16.0 2.0 0.13 12.4 0.5 2.1 1 1 1 2 2 2 1 Bd3614-like deaminase SNAD4 PF18750.1 KXS96693.1 - 0.015 15.4 0.0 0.067 13.3 0.0 1.8 2 0 0 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 4 DUF3725 PF12523.8 KXS96693.1 - 0.03 14.6 0.0 0.046 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3725) XOO_2897-deam PF14440.6 KXS96693.1 - 0.043 13.9 0.2 0.091 12.9 0.0 1.7 1 1 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase APOBEC_N PF08210.11 KXS96693.1 - 0.069 13.1 0.2 0.26 11.2 0.1 1.8 1 1 0 1 1 1 0 APOBEC-like N-terminal domain APOBEC2 PF18772.1 KXS96693.1 - 0.17 11.9 0.1 0.42 10.7 0.1 1.7 1 1 0 1 1 1 0 APOBEC2 NAD2 PF18782.1 KXS96693.1 - 0.22 11.6 0.0 0.48 10.5 0.0 1.7 1 1 0 1 1 1 0 Novel AID APOBEC clade 2 NAD1 PF18778.1 KXS96693.1 - 0.22 11.6 0.3 0.64 10.1 0.2 1.7 1 1 1 2 2 2 0 Novel AID APOBEC clade 1 AMP-binding PF00501.28 KXS96694.1 - 3e-79 266.6 0.0 3.8e-79 266.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXS96694.1 - 2.3e-15 57.3 0.0 4.4e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Sin3a_C PF16879.5 KXS96695.1 - 2.8e-71 240.6 2.9 2.8e-71 240.6 2.9 3.4 4 0 0 4 4 4 1 C-terminal domain of Sin3a protein PAH PF02671.21 KXS96695.1 - 3.7e-44 148.6 0.6 3e-16 59.3 0.0 3.8 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 KXS96695.1 - 5.2e-39 132.3 0.1 2.5e-38 130.1 0.0 2.2 2 0 0 2 2 2 1 Sin3 family co-repressor Mucin15 PF15672.5 KXS96695.1 - 0.13 11.8 0.2 0.3 10.6 0.2 1.6 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 Auts2 PF15336.6 KXS96695.1 - 0.78 9.8 15.4 0.095 12.8 8.0 2.7 2 0 0 2 2 2 0 Autism susceptibility gene 2 protein Na_Ca_ex PF01699.24 KXS96696.1 - 4e-29 101.5 27.2 1.2e-14 54.6 8.9 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF4010 PF13194.6 KXS96696.1 - 0.22 11.2 9.4 0.042 13.5 4.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4010) UPF0016 PF01169.19 KXS96696.1 - 8.6 6.8 14.9 0.69 10.3 0.8 4.2 3 1 1 4 4 4 0 Uncharacterized protein family UPF0016 Na_Ca_ex PF01699.24 KXS96697.1 - 2.1e-29 102.4 27.2 8.5e-15 55.0 8.9 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF4010 PF13194.6 KXS96697.1 - 1.6 8.3 13.0 0.03 14.0 4.7 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4010) UPF0016 PF01169.19 KXS96697.1 - 4.6 7.6 15.3 0.51 10.7 0.7 4.3 3 1 1 4 4 4 0 Uncharacterized protein family UPF0016 Ribosomal_L37ae PF01780.19 KXS96699.1 - 0.018 15.1 4.6 3.8 7.7 0.0 3.0 3 0 0 3 3 3 0 Ribosomal L37ae protein family DUF1949 PF09186.11 KXS96699.1 - 0.047 13.6 0.0 0.086 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1949) Uso1_p115_C PF04871.13 KXS96700.1 - 0.00099 19.5 12.4 0.012 15.9 4.0 2.4 2 0 0 2 2 2 2 Uso1 / p115 like vesicle tethering protein, C terminal region DASH_Dad3 PF08656.10 KXS96700.1 - 0.0023 18.0 7.6 0.032 14.3 3.2 3.4 2 1 0 2 2 2 1 DASH complex subunit Dad3 COG2 PF06148.11 KXS96700.1 - 0.0034 17.5 6.6 0.14 12.3 0.1 3.1 2 1 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 HALZ PF02183.18 KXS96700.1 - 0.07 13.4 0.7 12 6.2 0.1 2.9 1 1 1 2 2 2 0 Homeobox associated leucine zipper TelA PF05816.11 KXS96700.1 - 0.11 11.6 14.9 0.0092 15.1 6.6 2.3 1 1 2 3 3 3 0 Toxic anion resistance protein (TelA) Apolipoprotein PF01442.18 KXS96700.1 - 0.12 12.2 13.4 0.83 9.5 3.0 2.4 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain COG6 PF06419.11 KXS96700.1 - 0.15 10.3 12.0 0.0061 14.8 4.7 1.9 2 0 0 2 2 2 0 Conserved oligomeric complex COG6 CLZ PF16526.5 KXS96700.1 - 0.17 12.3 12.3 13 6.3 3.0 4.4 3 2 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Laminin_II PF06009.12 KXS96700.1 - 0.19 11.7 10.5 1.2 9.2 2.7 3.0 2 1 1 3 3 3 0 Laminin Domain II DUF948 PF06103.11 KXS96700.1 - 0.38 11.0 5.0 10 6.5 0.0 3.1 3 0 0 3 3 2 0 Bacterial protein of unknown function (DUF948) TPR_MLP1_2 PF07926.12 KXS96700.1 - 0.45 10.6 17.2 3.1 7.9 6.4 2.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.9 KXS96700.1 - 0.58 9.2 14.3 1.1 8.3 5.2 2.3 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 RmuC PF02646.16 KXS96700.1 - 0.83 8.7 12.9 0.3 10.2 3.1 2.5 3 0 0 3 3 2 0 RmuC family FlaC_arch PF05377.11 KXS96700.1 - 0.88 10.0 4.2 0.88 10.0 0.7 2.8 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) SKA1 PF07160.12 KXS96700.1 - 0.88 9.4 10.9 2.4 7.9 3.1 2.6 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 1 OmpH PF03938.14 KXS96700.1 - 0.94 9.8 16.6 5.6 7.3 7.7 2.6 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Syntaxin PF00804.25 KXS96700.1 - 0.98 9.0 13.2 3.7 7.2 0.8 3.3 4 0 0 4 4 4 0 Syntaxin Nsp1_C PF05064.13 KXS96700.1 - 1.5 8.6 8.4 4.9 7.0 0.1 2.9 3 0 0 3 3 2 0 Nsp1-like C-terminal region DUF5082 PF16888.5 KXS96700.1 - 1.6 9.1 14.0 1.2 9.4 8.4 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF5082) PMEI PF04043.15 KXS96700.1 - 2 8.8 6.3 3.5 8.0 0.5 2.4 2 0 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor CorA PF01544.18 KXS96700.1 - 2.1 7.6 8.5 6.5 6.0 4.9 2.9 1 1 0 2 2 2 0 CorA-like Mg2+ transporter protein IFT57 PF10498.9 KXS96700.1 - 3.1 6.7 12.9 0.16 10.9 5.7 2.1 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 NPV_P10 PF05531.12 KXS96700.1 - 5.2 7.6 11.1 17 5.9 4.3 4.0 5 1 1 6 6 4 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 KXS96700.1 - 5.3 5.8 14.2 3.5 6.4 5.8 2.4 2 0 0 2 2 2 0 Spc7 kinetochore protein SLX9 PF15341.6 KXS96700.1 - 6.5 7.2 11.4 22 5.5 4.7 2.7 2 1 0 2 2 2 0 Ribosome biogenesis protein SLX9 Alanine_zipper PF11839.8 KXS96700.1 - 7.3 7.0 9.3 1.5 9.2 4.5 2.3 2 0 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein DUF1664 PF07889.12 KXS96700.1 - 7.4 6.6 15.0 2.6 8.1 2.9 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) DUF724 PF05266.14 KXS96700.1 - 8.6 6.1 12.8 9.6 6.0 4.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF724) LPP PF04728.13 KXS96700.1 - 9.3 6.7 10.6 11 6.5 2.3 3.2 3 0 0 3 3 2 0 Lipoprotein leucine-zipper DnaJ_C PF01556.18 KXS96701.1 - 2.8e-40 137.8 0.2 3.6e-40 137.4 0.2 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KXS96701.1 - 5.6e-27 93.7 3.0 9.7e-27 92.9 3.0 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KXS96701.1 - 1.4e-16 60.5 21.5 2.6e-16 59.8 21.5 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 KXS96701.1 - 1.9 8.5 12.7 1.7 8.7 3.5 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Cytochrome_C7 PF14522.6 KXS96701.1 - 4.6 7.3 10.4 30 4.7 10.0 2.2 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c DUF2206 PF09971.9 KXS96702.1 - 0.09 11.5 0.0 0.098 11.4 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) URO-D PF01208.17 KXS96703.1 - 3e-126 421.2 0.0 3.4e-126 421.0 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) PAN_3 PF08277.12 KXS96704.1 - 0.061 13.1 3.8 0.22 11.4 3.8 1.9 1 0 0 1 1 1 0 PAN-like domain Chitin_synth_2 PF03142.15 KXS96711.1 - 9.9e-231 766.9 0.0 1.3e-230 766.5 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Cyt-b5 PF00173.28 KXS96711.1 - 1.5e-12 47.5 1.9 1.1e-08 35.1 0.0 3.0 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.11 KXS96711.1 - 4.2e-12 45.8 0.3 2e-11 43.7 0.5 2.0 2 0 0 2 2 2 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.6 KXS96711.1 - 1.4e-11 44.7 0.0 3.1e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Myosin_head PF00063.21 KXS96711.1 - 6.7e-11 41.1 0.0 1.4e-10 40.1 0.0 1.4 1 1 0 1 1 1 1 Myosin head (motor domain) Glyco_trans_2_3 PF13632.6 KXS96711.1 - 2.5e-10 40.6 3.4 2.5e-10 40.6 3.4 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 KXS96711.1 - 0.0035 16.8 0.0 0.0072 15.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KXS96711.1 - 0.021 14.6 0.0 0.56 10.0 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 Mit_KHE1 PF10173.9 KXS96712.1 - 1.1e-62 211.5 0.3 2e-62 210.7 0.3 1.4 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related UPF0449 PF15136.6 KXS96712.1 - 0.19 12.2 2.3 2.1 8.8 0.2 2.8 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 RNase_HII PF01351.18 KXS96713.1 - 1.8e-49 168.3 0.0 2.3e-49 168.0 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII LZ_Tnp_IS66 PF13007.7 KXS96715.1 - 0.087 13.6 0.9 0.35 11.7 0.1 2.0 1 1 1 2 2 2 0 Transposase C of IS166 homeodomain Mito_carr PF00153.27 KXS96716.1 - 1.6e-50 168.9 6.4 2.9e-16 59.2 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.27 KXS96717.1 - 1.4e-45 153.1 6.4 3.1e-16 59.1 0.0 3.4 2 2 1 3 3 3 3 Mitochondrial carrier protein PRiA4_ORF3 PF07929.11 KXS96718.1 - 3e-18 66.1 0.1 5.8e-17 61.9 0.0 2.4 1 1 1 2 2 2 1 Plasmid pRiA4b ORF-3-like protein SDA1 PF05285.12 KXS96718.1 - 0.00055 19.5 9.8 0.00067 19.2 9.8 1.1 1 0 0 1 1 1 1 SDA1 Cytomega_UL84 PF06284.11 KXS96718.1 - 0.15 10.5 0.7 0.17 10.3 0.7 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Nop14 PF04147.12 KXS96718.1 - 0.21 9.7 17.8 0.28 9.4 17.8 1.1 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 KXS96718.1 - 0.25 10.1 2.1 0.3 9.8 2.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TRAP_alpha PF03896.16 KXS96718.1 - 1.5 8.0 8.3 2.1 7.5 8.3 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CDC45 PF02724.14 KXS96718.1 - 2.1 6.5 14.0 2.7 6.2 14.0 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 KXS96718.1 - 9.1 5.5 18.4 12 5.1 18.4 1.1 1 0 0 1 1 1 0 BUD22 HSP70 PF00012.20 KXS96719.1 - 1.7e-11 43.1 0.5 6e-10 37.9 0.2 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 KXS96719.1 - 0.024 13.4 0.1 0.099 11.4 0.0 1.8 2 0 0 2 2 2 0 MreB/Mbl protein Pyr_redox_2 PF07992.14 KXS96720.1 - 1.7e-06 27.5 0.0 4.2e-05 22.9 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXS96720.1 - 0.0015 18.7 0.0 0.0052 17.0 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KXS96720.1 - 0.056 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Mito_carr PF00153.27 KXS96721.1 - 4.7e-42 141.8 9.4 1.5e-15 56.8 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Alpha-amylase PF00128.24 KXS96724.1 - 5.3e-17 62.4 0.1 5.3e-07 29.5 0.0 2.9 2 1 0 2 2 2 2 Alpha amylase, catalytic domain Siah-Interact_N PF09032.11 KXS96724.1 - 0.27 11.6 1.1 0.46 10.8 0.1 1.8 2 0 0 2 2 2 0 Siah interacting protein, N terminal Pyr_redox_2 PF07992.14 KXS96725.1 - 3.5e-39 134.8 0.0 4.1e-39 134.6 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXS96725.1 - 1.5e-10 41.5 0.5 1.2e-06 29.0 0.1 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXS96725.1 - 0.00027 20.1 0.1 0.4 9.7 0.0 2.4 3 0 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.6 KXS96725.1 - 0.0081 16.4 0.1 0.16 12.2 0.1 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXS96725.1 - 0.012 14.9 0.2 0.49 9.6 0.0 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXS96725.1 - 0.018 14.3 0.6 1.7 7.8 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.6 KXS96725.1 - 0.05 14.1 0.0 0.83 10.1 0.0 2.5 2 1 0 2 2 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 KXS96725.1 - 0.21 10.6 0.3 1 8.3 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.17 KXS96725.1 - 0.21 10.8 0.1 5.3 6.2 0.1 2.2 2 0 0 2 2 2 0 Thi4 family Tyrosinase PF00264.20 KXS96726.1 - 1.4e-51 176.0 4.4 2.4e-51 175.2 4.4 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase PAP_central PF04928.17 KXS96727.1 - 2.5e-96 321.5 0.0 3.7e-96 320.9 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase central domain Gtr1_RagA PF04670.12 KXS96727.1 - 3.4e-56 190.2 0.0 6.1e-56 189.4 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PAP_RNA-bind PF04926.15 KXS96727.1 - 2.9e-49 167.0 0.0 5.7e-49 166.0 0.0 1.5 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 KXS96727.1 - 2.1e-09 37.5 0.0 6.1e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain AAA_16 PF13191.6 KXS96727.1 - 0.069 13.5 0.1 0.42 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Chitin_synth_2 PF03142.15 KXS96728.1 - 1.2e-244 812.8 2.3 1.5e-244 812.5 2.3 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 KXS96728.1 - 1.2e-70 238.6 0.0 5.1e-70 236.5 0.0 1.8 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.28 KXS96728.1 - 1.1e-19 70.3 0.1 9.3e-16 57.7 0.0 3.0 3 0 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.11 KXS96728.1 - 3.2e-14 52.6 0.2 8.5e-14 51.2 0.2 1.8 1 0 0 1 1 1 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 KXS96728.1 - 4.2e-12 46.4 3.8 1.2e-11 44.9 3.8 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KXS96728.1 - 6.9e-12 45.7 0.1 1.1e-10 41.9 0.2 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KXS96728.1 - 0.00036 20.4 0.0 0.14 11.9 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 RsgA_GTPase PF03193.16 KXS96728.1 - 0.055 13.4 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 KXS96728.1 - 0.089 13.1 0.3 0.37 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KXS96728.1 - 0.1 12.1 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Glyco_transf_21 PF13506.6 KXS96728.1 - 0.27 10.7 0.6 1.6 8.2 0.6 2.1 1 1 0 1 1 1 0 Glycosyl transferase family 21 AtuA PF07287.11 KXS96729.1 - 1.3e-117 392.5 3.1 5.4e-116 387.1 3.1 2.0 1 1 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA RRM_2 PF04059.12 KXS96730.1 - 3.8e-26 91.1 0.1 8.1e-26 90.1 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 KXS96730.1 - 0.00099 18.9 0.4 1.4 8.8 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CHY PF05495.12 KXS96731.1 - 2e-12 47.4 22.2 3.7e-12 46.6 22.2 1.4 1 0 0 1 1 1 1 CHY zinc finger zf-RRPl_C4 PF17026.5 KXS96731.1 - 0.0038 17.3 4.0 0.0038 17.3 4.0 2.0 1 1 1 2 2 2 1 Putative ribonucleoprotein zinc-finger pf C4 type Cys_rich_KTR PF14205.6 KXS96731.1 - 0.0042 16.8 11.0 0.29 11.0 0.2 2.5 1 1 1 2 2 2 2 Cysteine-rich KTR Zn_Tnp_IS1595 PF12760.7 KXS96731.1 - 0.63 10.1 12.7 5.6 7.0 0.1 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain PolC_DP2 PF03833.13 KXS96731.1 - 3.7 5.3 7.8 4.1 5.1 7.8 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-Tim10_DDP PF02953.15 KXS96732.1 - 7.4e-23 80.0 4.4 9.5e-23 79.6 4.4 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Acetyltransf_19 PF18015.1 KXS96732.1 - 0.01 16.0 0.1 0.013 15.7 0.1 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GFA PF04828.14 KXS96734.1 - 2.2e-09 37.5 0.6 2.2e-09 37.5 0.6 1.9 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-LSD1 PF06943.12 KXS96734.1 - 3.6 7.5 9.2 4.7 7.2 0.3 2.9 3 0 0 3 3 3 0 LSD1 zinc finger NAP PF00956.18 KXS96735.1 - 1e-95 320.0 10.7 1e-95 320.0 10.7 1.8 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) RNA_pol_3_Rpc31 PF11705.8 KXS96735.1 - 1.4 9.1 31.3 0.55 10.4 20.8 2.5 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 NAP PF00956.18 KXS96736.1 - 1e-95 320.0 10.7 1e-95 320.0 10.7 1.8 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) RNA_pol_3_Rpc31 PF11705.8 KXS96736.1 - 1.4 9.1 31.3 0.55 10.4 20.8 2.5 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 DUF347 PF03988.12 KXS96737.1 - 0.014 15.6 0.9 0.028 14.6 0.9 1.5 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Sec15 PF04091.12 KXS96738.1 - 1.4e-105 353.2 0.5 1.4e-105 353.2 0.5 1.9 2 1 0 2 2 2 1 Exocyst complex subunit Sec15-like COG5 PF10392.9 KXS96738.1 - 0.00017 21.7 5.1 0.00017 21.7 5.1 2.5 2 0 0 2 2 2 1 Golgi transport complex subunit 5 COG2 PF06148.11 KXS96738.1 - 0.00024 21.2 5.0 0.00024 21.2 5.0 2.6 2 1 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Sec8_exocyst PF04048.14 KXS96738.1 - 0.00053 19.9 4.6 0.00053 19.9 4.6 3.1 3 0 0 3 3 3 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 KXS96738.1 - 0.0052 16.1 6.7 0.012 14.9 6.7 1.6 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF3510 PF12022.8 KXS96738.1 - 0.01 16.2 6.6 3.6 8.0 0.0 4.3 4 1 1 5 5 5 0 Domain of unknown function (DUF3510) IFT57 PF10498.9 KXS96738.1 - 0.017 14.1 3.5 0.035 13.1 3.5 1.4 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 BET PF17035.5 KXS96738.1 - 0.026 14.7 0.1 2.7 8.2 0.0 3.0 2 0 0 2 2 2 0 Bromodomain extra-terminal - transcription regulation Vps51 PF08700.11 KXS96738.1 - 0.083 13.0 1.4 0.51 10.5 1.1 2.6 1 1 0 1 1 1 0 Vps51/Vps67 TPR_MLP1_2 PF07926.12 KXS96738.1 - 0.098 12.7 6.6 0.056 13.5 1.9 2.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein PrcB_C PF14343.6 KXS96738.1 - 0.35 11.0 0.8 0.74 10.0 0.8 1.5 1 0 0 1 1 1 0 PrcB C-terminal YkyA PF10368.9 KXS96738.1 - 0.82 9.3 5.2 0.46 10.1 2.1 2.2 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein HDA2-3 PF11496.8 KXS96739.1 - 1.3e-22 80.3 0.0 2.3e-11 43.4 0.0 2.4 2 0 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 PB1 PF00564.24 KXS96739.1 - 0.064 13.2 1.3 0.23 11.4 0.3 2.3 2 0 0 2 2 2 0 PB1 domain Myb_CC_LHEQLE PF14379.6 KXS96739.1 - 0.5 10.1 10.5 0.13 12.0 2.5 2.7 2 0 0 2 2 2 0 MYB-CC type transfactor, LHEQLE motif GAS PF13851.6 KXS96739.1 - 7.9 5.8 31.0 0.32 10.3 5.0 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding FliD_N PF02465.18 KXS96739.1 - 8.6 7.1 11.5 2.1 9.1 1.4 3.1 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Ribosomal_L28e PF01778.17 KXS96740.1 - 9.2e-39 132.8 1.4 9.2e-39 132.8 1.4 1.7 2 0 0 2 2 2 1 Ribosomal L28e protein family DUF2015 PF09435.10 KXS96741.1 - 3e-41 139.8 0.0 3.7e-41 139.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Phosphodiest PF01663.22 KXS96742.1 - 6.1e-14 52.4 0.8 2.5e-09 37.2 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KXS96742.1 - 2.6e-06 27.1 0.1 1.9e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.18 KXS96742.1 - 0.019 14.3 0.1 0.033 13.6 0.1 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily RRM_1 PF00076.22 KXS96743.1 - 3.5e-32 110.0 0.0 3.1e-15 55.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXS96743.1 - 0.00027 20.5 0.0 0.041 13.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXS96743.1 - 0.0088 16.1 0.0 0.038 14.1 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif OB_RNB PF08206.11 KXS96743.1 - 0.06 13.0 0.4 6.6 6.5 0.0 2.4 2 0 0 2 2 2 0 Ribonuclease B OB domain Polysacc_deac_1 PF01522.21 KXS96744.1 - 2.6e-11 43.5 0.0 8.1e-10 38.7 0.0 2.2 2 0 0 2 2 2 1 Polysaccharide deacetylase DUF2334 PF10096.9 KXS96744.1 - 0.028 14.1 0.1 0.13 11.9 0.1 1.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) zf-MYST PF17772.1 KXS96744.1 - 0.12 11.9 0.1 0.26 10.9 0.1 1.5 1 0 0 1 1 1 0 MYST family zinc finger domain DUF3431 PF11913.8 KXS96745.1 - 9.6e-64 215.1 0.0 2.9e-61 207.0 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3431) Exo_endo_phos PF03372.23 KXS96746.1 - 1.5e-08 34.4 0.1 4.6e-08 32.9 0.0 1.9 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Rap1-DNA-bind PF09197.10 KXS96746.1 - 0.04 14.5 0.2 0.098 13.3 0.2 1.6 1 0 0 1 1 1 0 Rap1, DNA-binding HET PF06985.11 KXS96748.1 - 3.2e-26 92.5 0.0 4.6e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Kdo PF06293.14 KXS96753.1 - 1.8e-14 53.6 0.0 2.5e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXS96753.1 - 9.1e-09 35.6 0.1 0.00085 19.3 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.25 KXS96753.1 - 3.1e-08 33.3 0.0 3.8e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KXS96753.1 - 3.7e-07 29.9 0.0 5.9e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 RIO1 family EcKinase PF02958.20 KXS96753.1 - 2.8e-05 23.6 0.0 3.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Pkinase_fungal PF17667.1 KXS96753.1 - 8.8e-05 21.4 0.0 0.00011 21.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 KXS96753.1 - 0.00061 19.2 0.0 0.00074 18.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 KXS96753.1 - 0.035 13.7 0.0 0.066 12.8 0.0 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase MTCP1 PF08991.10 KXS96754.1 - 3.6e-29 100.8 12.5 4.2e-29 100.6 12.5 1.0 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 KXS96754.1 - 0.0012 18.9 10.7 0.0022 18.1 10.7 1.4 1 0 0 1 1 1 1 CHCH domain ELFV_dehydrog PF00208.21 KXS96754.1 - 0.16 11.7 0.2 0.21 11.3 0.2 1.1 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase EGF_MSP1_1 PF12946.7 KXS96754.1 - 0.75 9.9 8.7 0.38 10.9 5.7 2.1 2 1 0 2 2 2 0 MSP1 EGF domain 1 tRNA_lig_CPD PF08302.11 KXS96755.1 - 4.6e-88 294.9 0.0 6.7e-88 294.4 0.0 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain RNA_lig_T4_1 PF09511.10 KXS96755.1 - 9e-84 280.7 0.1 1.5e-83 280.0 0.1 1.4 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.11 KXS96755.1 - 5.1e-51 173.1 0.0 1.1e-50 172.1 0.0 1.5 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_18 PF13238.6 KXS96755.1 - 0.0075 16.8 0.3 0.15 12.6 0.1 3.0 3 1 0 3 3 3 1 AAA domain Phage_TAC_4 PF08748.11 KXS96755.1 - 0.054 13.8 0.0 0.19 12.0 0.0 1.9 1 0 0 1 1 1 0 Phage tail assembly chaperone ATP-synt_ab PF00006.25 KXS96756.1 - 6.3e-72 241.7 0.0 9.1e-72 241.2 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 KXS96756.1 - 1e-46 158.4 0.5 1.7e-46 157.6 0.5 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 KXS96756.1 - 1.1e-15 57.9 3.7 3.4e-15 56.3 3.7 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATP-synt_ab PF00006.25 KXS96757.1 - 4.3e-59 199.7 0.0 9.3e-33 113.7 0.0 2.3 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 KXS96757.1 - 1.4e-46 157.9 0.5 2.4e-46 157.1 0.5 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 KXS96757.1 - 1.6e-15 57.4 3.7 4.6e-15 55.9 3.7 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF676 PF05057.14 KXS96758.1 - 5.2e-47 160.2 0.0 9.4e-47 159.3 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.25 KXS96758.1 - 0.001 18.9 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KXS96758.1 - 0.0012 19.5 0.1 0.002 18.7 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family AroM PF07302.11 KXS96758.1 - 0.048 13.0 0.0 0.083 12.3 0.0 1.3 1 0 0 1 1 1 0 AroM protein PE-PPE PF08237.11 KXS96758.1 - 0.16 11.5 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain DLH PF01738.18 KXS96758.1 - 0.18 11.3 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF962 PF06127.11 KXS96759.1 - 2.3e-22 78.9 2.7 3.4e-22 78.3 2.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF962) CorA PF01544.18 KXS96759.1 - 2.5 7.4 4.3 3.4 6.9 4.3 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Zip PF02535.22 KXS96760.1 - 7.3e-56 189.8 10.7 1.8e-54 185.2 10.7 2.2 1 1 0 1 1 1 1 ZIP Zinc transporter DUF4134 PF13572.6 KXS96760.1 - 0.12 12.7 1.8 2.8 8.3 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4134) Zip PF02535.22 KXS96761.1 - 7.3e-56 189.8 10.7 1.8e-54 185.2 10.7 2.2 1 1 0 1 1 1 1 ZIP Zinc transporter DUF4134 PF13572.6 KXS96761.1 - 0.12 12.7 1.8 2.8 8.3 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4134) DUF962 PF06127.11 KXS96762.1 - 7e-16 58.1 2.5 1.2e-15 57.4 2.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF962) CorA PF01544.18 KXS96762.1 - 0.71 9.1 2.6 0.97 8.7 2.6 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Zip PF02535.22 KXS96763.1 - 7.3e-56 189.8 10.7 1.8e-54 185.2 10.7 2.2 1 1 0 1 1 1 1 ZIP Zinc transporter DUF4134 PF13572.6 KXS96763.1 - 0.12 12.7 1.8 2.8 8.3 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4134) Rad60-SLD PF11976.8 KXS96764.1 - 1.7e-20 72.6 0.1 2.2e-20 72.2 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KXS96764.1 - 1.6e-09 37.4 0.1 2.1e-09 37.0 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KXS96765.1 - 1.7e-20 72.6 0.1 2.2e-20 72.2 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KXS96765.1 - 1.6e-09 37.4 0.1 2.1e-09 37.0 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family HTH_38 PF13936.6 KXS96766.1 - 4.4e-18 64.8 2.1 0.0008 19.1 0.0 4.3 4 0 0 4 4 4 4 Helix-turn-helix domain Myb_DNA-binding PF00249.31 KXS96766.1 - 1e-14 54.4 15.9 5.6e-06 26.5 0.5 5.6 5 1 0 5 5 5 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXS96766.1 - 9.5e-14 51.4 7.6 5.2e-07 29.8 0.1 4.5 3 1 2 5 5 5 2 Myb-like DNA-binding domain HTH_23 PF13384.6 KXS96766.1 - 1.1e-12 47.3 1.1 0.065 13.1 0.0 5.4 5 0 0 5 5 5 4 Homeodomain-like domain GcrA PF07750.11 KXS96766.1 - 6.8e-11 42.8 4.3 0.00068 20.1 0.2 4.0 3 1 1 4 4 4 3 GcrA cell cycle regulator Sigma70_r4_2 PF08281.12 KXS96766.1 - 2.6e-10 39.8 0.7 0.00032 20.3 0.0 3.9 4 0 0 4 4 4 2 Sigma-70, region 4 GerE PF00196.19 KXS96766.1 - 4e-07 29.5 0.4 0.38 10.3 0.0 4.5 5 0 0 5 5 5 2 Bacterial regulatory proteins, luxR family HTH_7 PF02796.15 KXS96766.1 - 1.6e-06 28.1 0.0 0.41 10.8 0.0 4.3 4 0 0 4 4 4 1 Helix-turn-helix domain of resolvase Terminase_5 PF06056.12 KXS96766.1 - 9.2e-06 25.5 0.4 1.3 9.0 0.0 4.1 5 0 0 5 5 4 2 Putative ATPase subunit of terminase (gpP-like) HTH_Tnp_Tc3_1 PF11427.8 KXS96766.1 - 9.5e-06 25.4 0.4 0.058 13.2 0.0 4.0 4 0 0 4 4 4 1 Tc3 transposase MADF_DNA_bdg PF10545.9 KXS96766.1 - 0.0016 18.7 0.7 0.29 11.5 0.1 3.0 2 1 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like RepB PF07506.11 KXS96766.1 - 0.0016 18.5 0.0 0.062 13.4 0.0 2.8 2 2 1 3 3 3 1 RepB plasmid partitioning protein Sigma70_r4 PF04545.16 KXS96766.1 - 0.002 17.6 3.1 0.055 13.0 0.1 3.9 5 0 0 5 5 5 1 Sigma-70, region 4 Ribosomal_S13_N PF08069.12 KXS96766.1 - 0.0054 16.7 0.1 3.7 7.7 0.0 2.9 2 0 0 2 2 2 1 Ribosomal S13/S15 N-terminal domain KorB PF08535.10 KXS96766.1 - 0.0059 16.6 0.0 2.1 8.4 0.0 3.4 3 0 0 3 3 3 1 KorB domain HTH_40 PF14493.6 KXS96766.1 - 0.015 15.7 0.0 10 6.7 0.0 3.6 2 1 2 4 4 4 0 Helix-turn-helix domain HTH_11 PF08279.12 KXS96766.1 - 0.033 14.1 0.1 5.2 7.1 0.0 3.4 3 1 0 3 3 3 0 HTH domain DUF2774 PF11242.8 KXS96766.1 - 0.098 12.9 1.3 30 4.9 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2774) Myb_DNA-bind_4 PF13837.6 KXS96766.1 - 0.1 13.0 0.1 0.1 13.0 0.1 3.0 3 1 0 3 3 2 0 Myb/SANT-like DNA-binding domain NPA PF16469.5 KXS96766.1 - 0.1 13.2 0.1 52 4.4 0.0 3.8 4 0 0 4 4 4 0 Nematode polyprotein allergen ABA-1 F_bP_aldolase PF01116.20 KXS96770.1 - 1.9e-83 280.2 0.0 2.2e-83 280.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II STAS PF01740.21 KXS96770.1 - 0.038 13.6 0.0 0.085 12.5 0.0 1.6 1 0 0 1 1 1 0 STAS domain Sugar_tr PF00083.24 KXS96771.1 - 1.9e-87 294.0 22.2 2.2e-87 293.8 22.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS96771.1 - 5e-27 94.8 32.5 2.9e-24 85.7 27.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXS96771.1 - 0.0002 19.9 0.1 0.0002 19.9 0.1 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Orf78 PF06024.12 KXS96771.1 - 1.8 8.9 4.5 0.31 11.3 0.2 1.9 2 0 0 2 2 2 0 Orf78 (ac78) ADH_N PF08240.12 KXS96772.1 - 1.3e-31 108.7 0.3 1.3e-31 108.7 0.3 2.5 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXS96772.1 - 1.6e-25 89.6 0.1 2.6e-25 88.9 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXS96772.1 - 1e-06 28.4 0.1 1e-05 25.2 0.1 2.1 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KXS96772.1 - 9.3e-06 26.7 0.0 3.3e-05 24.9 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 KXS96772.1 - 0.0028 18.3 0.0 0.0059 17.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain AlaDh_PNT_C PF01262.21 KXS96772.1 - 0.012 14.9 0.4 0.018 14.3 0.4 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KXS96772.1 - 0.059 12.7 0.3 0.1 12.0 0.3 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Hexapep PF00132.24 KXS96772.1 - 0.12 12.1 1.8 0.23 11.2 0.8 2.0 2 0 0 2 2 2 0 Bacterial transferase hexapeptide (six repeats) CMAS PF02353.20 KXS96772.1 - 0.24 10.7 0.2 0.36 10.1 0.2 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase IU_nuc_hydro PF01156.19 KXS96775.1 - 7.5e-33 114.4 0.2 4.6e-21 75.7 0.3 2.8 2 1 0 2 2 2 2 Inosine-uridine preferring nucleoside hydrolase BH3 PF15285.6 KXS96775.1 - 0.0052 16.5 0.0 0.014 15.1 0.0 1.7 1 0 0 1 1 1 1 Beclin-1 BH3 domain, Bcl-2-interacting Transketolase_C PF02780.20 KXS96775.1 - 0.13 12.2 0.0 0.68 9.8 0.0 2.0 2 0 0 2 2 2 0 Transketolase, C-terminal domain IU_nuc_hydro PF01156.19 KXS96776.1 - 2.6e-50 171.7 0.0 9.6e-39 133.7 0.0 2.9 2 1 0 2 2 2 2 Inosine-uridine preferring nucleoside hydrolase BH3 PF15285.6 KXS96776.1 - 0.0067 16.2 0.0 0.018 14.8 0.0 1.7 1 0 0 1 1 1 1 Beclin-1 BH3 domain, Bcl-2-interacting Transketolase_C PF02780.20 KXS96776.1 - 0.2 11.6 0.0 0.92 9.4 0.0 2.0 2 0 0 2 2 2 0 Transketolase, C-terminal domain PTPA PF03095.15 KXS96777.1 - 3.9e-109 364.7 0.0 4.6e-109 364.5 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein MFS_1 PF07690.16 KXS96778.1 - 7.2e-39 133.7 32.4 7.2e-39 133.7 32.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Cytochrom_B561 PF03188.16 KXS96778.1 - 0.25 11.4 8.3 0.36 10.9 6.1 2.4 1 1 1 2 2 2 0 Eukaryotic cytochrome b561 Nop16 PF09420.10 KXS96779.1 - 2.3e-63 214.0 15.4 2.6e-63 213.9 15.4 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 DUF5024 PF16427.5 KXS96779.1 - 0.013 15.8 1.7 0.058 13.7 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF5024) Not3 PF04065.15 KXS96779.1 - 0.16 11.4 0.2 0.16 11.4 0.2 2.6 1 1 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component GTP_cyclohydro2 PF00925.20 KXS96781.1 - 7.8e-57 191.4 0.0 1.8e-56 190.2 0.0 1.5 1 1 0 1 1 1 1 GTP cyclohydrolase II adh_short_C2 PF13561.6 KXS96782.1 - 8.6e-51 172.7 0.0 1.1e-50 172.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS96782.1 - 6.3e-46 156.3 0.3 7.5e-46 156.0 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS96782.1 - 5.4e-10 39.5 0.1 8e-10 38.9 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXS96782.1 - 0.00074 18.7 0.0 0.00092 18.4 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KXS96782.1 - 0.011 15.2 0.1 0.025 14.1 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXS96782.1 - 0.046 12.7 0.0 0.058 12.4 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short_C2 PF13561.6 KXS96783.1 - 5.7e-54 183.1 0.0 7.1e-54 182.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS96783.1 - 8.6e-47 159.1 0.1 1.2e-46 158.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS96783.1 - 6.3e-07 29.5 0.1 1.1e-06 28.8 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS96783.1 - 0.13 11.7 0.1 0.37 10.2 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.6 KXS96784.1 - 8.6e-51 172.7 0.0 1.1e-50 172.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS96784.1 - 6.3e-46 156.3 0.3 7.5e-46 156.0 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS96784.1 - 5.4e-10 39.5 0.1 8e-10 38.9 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXS96784.1 - 0.00074 18.7 0.0 0.00092 18.4 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KXS96784.1 - 0.011 15.2 0.1 0.025 14.1 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXS96784.1 - 0.046 12.7 0.0 0.058 12.4 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short_C2 PF13561.6 KXS96785.1 - 5.7e-54 183.1 0.0 7.1e-54 182.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS96785.1 - 8.6e-47 159.1 0.1 1.2e-46 158.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS96785.1 - 6.3e-07 29.5 0.1 1.1e-06 28.8 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS96785.1 - 0.13 11.7 0.1 0.37 10.2 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.6 KXS96786.1 - 8.6e-51 172.7 0.0 1.1e-50 172.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS96786.1 - 6.3e-46 156.3 0.3 7.5e-46 156.0 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS96786.1 - 5.4e-10 39.5 0.1 8e-10 38.9 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXS96786.1 - 0.00074 18.7 0.0 0.00092 18.4 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KXS96786.1 - 0.011 15.2 0.1 0.025 14.1 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXS96786.1 - 0.046 12.7 0.0 0.058 12.4 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short_C2 PF13561.6 KXS96787.1 - 1.1e-50 172.4 0.0 1.4e-50 172.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS96787.1 - 7.9e-46 156.0 0.3 9.5e-46 155.7 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS96787.1 - 6.6e-10 39.2 0.1 9.9e-10 38.6 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXS96787.1 - 0.0009 18.5 0.1 0.0011 18.1 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KXS96787.1 - 0.015 14.8 0.1 0.031 13.7 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXS96787.1 - 0.053 12.5 0.0 0.07 12.1 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short_C2 PF13561.6 KXS96788.1 - 5.7e-54 183.1 0.0 7.1e-54 182.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS96788.1 - 8.6e-47 159.1 0.1 1.2e-46 158.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS96788.1 - 6.3e-07 29.5 0.1 1.1e-06 28.8 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS96788.1 - 0.13 11.7 0.1 0.37 10.2 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.6 KXS96789.1 - 1.1e-50 172.4 0.0 1.4e-50 172.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS96789.1 - 7.9e-46 156.0 0.3 9.5e-46 155.7 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS96789.1 - 6.6e-10 39.2 0.1 9.9e-10 38.6 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXS96789.1 - 0.0009 18.5 0.1 0.0011 18.1 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KXS96789.1 - 0.015 14.8 0.1 0.031 13.7 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXS96789.1 - 0.053 12.5 0.0 0.07 12.1 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short_C2 PF13561.6 KXS96790.1 - 8.6e-51 172.7 0.0 1.1e-50 172.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS96790.1 - 6.3e-46 156.3 0.3 7.5e-46 156.0 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS96790.1 - 5.4e-10 39.5 0.1 8e-10 38.9 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXS96790.1 - 0.00074 18.7 0.0 0.00092 18.4 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KXS96790.1 - 0.011 15.2 0.1 0.025 14.1 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXS96790.1 - 0.046 12.7 0.0 0.058 12.4 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short_C2 PF13561.6 KXS96791.1 - 6.4e-54 183.0 0.0 8.2e-54 182.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS96791.1 - 9.4e-47 159.0 0.1 1.3e-46 158.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS96791.1 - 5.5e-07 29.7 0.1 1.1e-06 28.6 0.1 1.6 1 0 0 1 1 1 1 KR domain Fungal_trans_2 PF11951.8 KXS96792.1 - 2.8e-18 65.9 0.0 3.9e-17 62.1 0.0 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS96792.1 - 1e-06 28.7 5.8 1e-06 28.7 5.8 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXS96792.1 - 0.1 11.6 0.2 0.18 10.8 0.2 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain Dak1 PF02733.17 KXS96793.1 - 2.1e-100 335.6 0.0 3.1e-100 335.1 0.0 1.3 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 KXS96793.1 - 6.8e-35 120.5 3.2 6.8e-35 120.5 3.2 1.6 2 0 0 2 2 2 1 DAK2 domain adh_short_C2 PF13561.6 KXS96794.1 - 2.6e-58 197.3 0.0 3.4e-58 197.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS96794.1 - 7.3e-45 152.8 0.1 8.8e-45 152.6 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS96794.1 - 5.2e-10 39.5 0.1 1.6e-09 37.9 0.1 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS96794.1 - 3.5e-05 23.4 0.2 5.8e-05 22.7 0.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KXS96794.1 - 0.0037 17.2 0.1 0.0055 16.6 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 KXS96794.1 - 0.011 15.8 0.2 0.018 15.1 0.2 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain TrkA_N PF02254.18 KXS96794.1 - 0.02 15.1 0.1 0.038 14.2 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Glyco_trans_4_2 PF13477.6 KXS96794.1 - 0.052 13.6 0.0 0.094 12.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like F420_oxidored PF03807.17 KXS96794.1 - 0.068 13.8 0.1 0.12 12.9 0.1 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Ssu72 PF04722.13 KXS96796.1 - 2.8e-80 268.4 0.0 3.3e-80 268.1 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein IMPDH PF00478.25 KXS96797.1 - 2.8e-126 421.2 4.9 3.4e-126 420.9 4.9 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 KXS96797.1 - 2.3e-17 63.2 0.0 6.5e-08 32.9 0.0 2.7 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 KXS96797.1 - 3.5e-08 32.9 1.1 7.6e-08 31.8 1.1 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.15 KXS96797.1 - 4e-05 23.2 3.3 0.007 15.8 3.0 2.4 2 0 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.21 KXS96797.1 - 9.3e-05 22.0 2.2 0.023 14.2 0.2 2.4 1 1 1 2 2 2 2 Histidine biosynthesis protein YpsA PF06908.11 KXS96797.1 - 0.0088 16.0 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 1 YspA SLOG family PK PF00224.21 KXS96797.1 - 0.062 12.2 0.0 0.12 11.3 0.0 1.5 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain Aldolase PF01081.19 KXS96797.1 - 0.087 12.2 2.3 0.17 11.3 0.3 2.3 2 0 0 2 2 2 0 KDPG and KHG aldolase ThiG PF05690.14 KXS96797.1 - 0.13 11.5 2.9 0.092 12.0 1.1 1.6 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.17 KXS96797.1 - 0.16 11.1 5.1 0.29 10.2 5.1 1.3 1 0 0 1 1 1 0 Conserved region in glutamate synthase GFA PF04828.14 KXS96799.1 - 3e-19 69.2 1.2 5.7e-19 68.3 0.2 1.8 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme RibD_C PF01872.17 KXS96800.1 - 4.2e-38 131.2 0.0 5e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain Pkinase PF00069.25 KXS96801.1 - 8.2e-70 235.2 0.0 1.4e-69 234.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS96801.1 - 3.7e-33 114.9 0.0 1.3e-31 109.8 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXS96801.1 - 0.007 15.7 0.7 3.2 7.0 0.0 2.6 3 0 0 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 KXS96801.1 - 0.014 14.2 0.0 0.028 13.2 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 KXS96801.1 - 0.026 14.1 0.5 0.051 13.2 0.5 1.4 1 0 0 1 1 1 0 RIO1 family adh_short_C2 PF13561.6 KXS96802.1 - 1.3e-61 208.2 0.2 1.5e-61 208.0 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS96802.1 - 5e-43 146.8 0.5 6e-43 146.6 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS96802.1 - 2.3e-15 57.0 0.2 3.6e-15 56.3 0.2 1.3 1 0 0 1 1 1 1 KR domain Spore_IV_A PF09547.10 KXS96802.1 - 0.1 11.5 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) SRF-TF PF00319.18 KXS96802.1 - 0.14 11.6 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 SRF-type transcription factor (DNA-binding and dimerisation domain) Oxysterol_BP PF01237.18 KXS96803.1 - 5.3e-90 302.0 0.1 9.3e-88 294.6 0.1 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein PCRF PF03462.18 KXS96803.1 - 0.24 11.3 1.4 0.59 10.0 0.0 2.2 3 0 0 3 3 3 0 PCRF domain DUF2935 PF11155.8 KXS96804.1 - 0.049 14.0 0.0 0.085 13.2 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) RasGAP_C PF03836.15 KXS96805.1 - 3e-50 169.9 1.6 3e-50 169.9 1.6 2.4 2 0 0 2 2 2 1 RasGAP C-terminus RasGAP PF00616.19 KXS96805.1 - 9e-34 117.0 0.0 4.5e-33 114.7 0.0 2.1 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase CH PF00307.31 KXS96805.1 - 2e-09 37.6 0.1 1.8e-08 34.5 0.0 2.3 2 0 0 2 2 2 1 Calponin homology (CH) domain IQ PF00612.27 KXS96805.1 - 0.0047 16.6 62.5 0.42 10.6 0.1 15.0 16 0 0 16 16 16 3 IQ calmodulin-binding motif NleF_casp_inhib PF16809.5 KXS96805.1 - 0.077 12.9 0.3 0.24 11.3 0.3 1.8 1 0 0 1 1 1 0 NleF caspase inhibitor Sdh5 PF03937.16 KXS96806.1 - 2e-24 85.3 0.2 6.3e-24 83.7 0.2 1.8 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase p450 PF00067.22 KXS96807.1 - 0.14 10.9 0.1 0.15 10.7 0.1 1.0 1 0 0 1 1 1 0 Cytochrome P450 Herpes_LMP1 PF05297.11 KXS96808.1 - 0.11 11.7 0.2 0.12 11.5 0.2 1.0 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) p450 PF00067.22 KXS96808.1 - 0.56 8.9 1.5 0.56 8.9 1.5 1.0 1 0 0 1 1 1 0 Cytochrome P450 Fungal_trans PF04082.18 KXS96809.1 - 5.3e-14 51.9 0.0 2.9e-13 49.5 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS96809.1 - 4.9e-06 26.6 14.4 8.3e-06 25.8 14.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spectrin PF00435.21 KXS96810.1 - 0.016 15.7 2.2 0.025 15.0 2.2 1.2 1 0 0 1 1 1 0 Spectrin repeat DBC1 PF14443.6 KXS96810.1 - 0.016 15.2 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 DBC1 ABC_tran PF00005.27 KXS96811.1 - 6.4e-09 36.4 0.0 1e-08 35.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter DUF3072 PF11272.8 KXS96812.1 - 0.0058 16.5 0.2 0.0086 15.9 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3072) TcpE PF12648.7 KXS96812.1 - 0.0096 16.4 0.3 0.012 16.1 0.3 1.1 1 0 0 1 1 1 1 TcpE family DUF1345 PF07077.11 KXS96812.1 - 0.019 14.6 0.1 0.021 14.5 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1345) zf-C2H2_4 PF13894.6 KXS96814.1 - 1.7e-09 37.7 17.5 0.065 14.1 0.1 5.1 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2 PF00096.26 KXS96814.1 - 4.5e-09 36.3 22.5 0.0099 16.3 4.3 5.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type Ank_2 PF12796.7 KXS96814.1 - 1.5e-07 31.9 0.1 9.8e-06 26.1 0.0 3.0 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 KXS96814.1 - 2.1e-07 31.1 0.4 0.29 11.7 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat zf-C2H2_jaz PF12171.8 KXS96814.1 - 3.8e-05 23.8 10.9 0.1 12.9 0.0 4.6 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding Ank_4 PF13637.6 KXS96814.1 - 5.5e-05 23.6 0.0 0.0053 17.3 0.0 3.6 3 1 1 4 4 4 1 Ankyrin repeats (many copies) zf-met PF12874.7 KXS96814.1 - 0.0037 17.6 3.3 1.5 9.3 0.5 3.9 3 0 0 3 3 3 1 Zinc-finger of C2H2 type Ank_5 PF13857.6 KXS96814.1 - 0.0083 16.4 0.0 0.25 11.7 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DZR PF12773.7 KXS96814.1 - 0.0095 15.9 5.5 0.78 9.8 0.2 3.1 3 0 0 3 3 3 2 Double zinc ribbon zf-C2H2_11 PF16622.5 KXS96814.1 - 0.01 15.5 11.5 1.3 8.9 0.1 3.8 3 0 0 3 3 3 0 zinc-finger C2H2-type Ank_3 PF13606.6 KXS96814.1 - 0.018 15.5 0.0 26 5.8 0.0 3.9 5 0 0 5 5 3 0 Ankyrin repeat zf-C2H2_2 PF12756.7 KXS96814.1 - 0.095 13.0 17.8 0.072 13.4 2.5 4.4 2 2 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 KXS96814.1 - 0.1 13.3 7.5 5.8 7.6 0.5 3.5 2 2 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats HypA PF01155.19 KXS96814.1 - 0.12 12.4 6.2 1.4 9.0 0.5 3.1 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF5535 PF17687.1 KXS96814.1 - 0.16 12.2 1.3 0.52 10.5 1.3 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5535) zf-H2C2_2 PF13465.6 KXS96814.1 - 4.3 7.9 21.0 11 6.7 0.5 5.3 5 0 0 5 5 4 0 Zinc-finger double domain HNH_5 PF14279.6 KXS96814.1 - 6.5 6.7 12.9 1.7 8.6 1.1 4.0 4 1 0 4 4 4 0 HNH endonuclease DUF3043 PF11241.8 KXS96815.1 - 0.0089 16.1 3.3 0.0089 16.1 3.3 3.8 5 0 0 5 5 5 2 Protein of unknown function (DUF3043) DNA_pol_phi PF04931.13 KXS96815.1 - 2.7 6.0 4.2 0.94 7.5 1.1 1.7 2 0 0 2 2 2 0 DNA polymerase phi DUF5127 PF17168.4 KXS96817.1 - 1.9e-80 269.9 13.8 3e-80 269.3 13.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KXS96817.1 - 6.5e-70 234.3 2.5 1.5e-69 233.1 0.1 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KXS96817.1 - 1.7e-58 197.8 1.6 2.4e-58 197.3 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KXS96817.1 - 1.3e-07 31.1 0.0 3.7e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) Glyco_hydr_116N PF12215.8 KXS96817.1 - 0.0016 18.0 2.1 0.0029 17.1 2.1 1.4 1 0 0 1 1 1 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term DUF5127 PF17168.4 KXS96818.1 - 1.9e-80 269.9 13.8 3e-80 269.3 13.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KXS96818.1 - 6.5e-70 234.3 2.5 1.5e-69 233.1 0.1 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KXS96818.1 - 1.7e-58 197.8 1.6 2.4e-58 197.3 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KXS96818.1 - 1.3e-07 31.1 0.0 3.7e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) Glyco_hydr_116N PF12215.8 KXS96818.1 - 0.0016 18.0 2.1 0.0029 17.1 2.1 1.4 1 0 0 1 1 1 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term Lipase_GDSL_2 PF13472.6 KXS96824.1 - 4.6e-10 40.2 2.6 6.2e-10 39.8 2.6 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXS96824.1 - 1.3e-06 28.5 0.1 1.8e-06 28.1 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ALGX PF16822.5 KXS96824.1 - 0.04 13.6 0.4 0.063 13.0 0.1 1.5 2 0 0 2 2 2 0 SGNH hydrolase-like domain, acetyltransferase AlgX DUF2229 PF09989.9 KXS96824.1 - 0.045 13.4 0.0 0.082 12.5 0.0 1.3 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) Hepar_II_III PF07940.13 KXS96824.1 - 0.047 13.3 2.4 0.06 13.0 0.8 1.8 2 0 0 2 2 2 0 Heparinase II/III-like protein Mito_carr PF00153.27 KXS96827.1 - 7.4e-48 160.4 0.8 4.2e-17 61.8 0.0 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF1869 PF08956.10 KXS96827.1 - 0.26 11.2 4.4 0.96 9.4 1.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1869) adh_short_C2 PF13561.6 KXS96828.1 - 6.9e-48 163.2 1.0 6.4e-43 147.0 0.2 2.0 1 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS96828.1 - 1.6e-45 155.0 0.1 1.9e-45 154.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS96828.1 - 3.3e-15 56.5 0.1 5.3e-15 55.8 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS96828.1 - 1.4e-08 34.6 0.1 4.9e-08 32.7 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KXS96828.1 - 0.027 13.6 0.3 0.15 11.1 0.1 2.2 2 1 0 2 2 2 0 RmlD substrate binding domain Glug PF07581.12 KXS96828.1 - 0.032 14.6 0.8 17 6.1 0.1 3.1 2 0 0 2 2 2 0 The GLUG motif Dak1_2 PF13684.6 KXS96828.1 - 0.077 12.1 0.1 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 Dihydroxyacetone kinase family THF_DHG_CYH_C PF02882.19 KXS96828.1 - 0.083 12.2 0.2 0.13 11.5 0.2 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain CRIM PF16978.5 KXS96830.1 - 7.9e-41 139.5 0.0 7.9e-41 139.5 0.0 1.6 2 0 0 2 2 2 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 KXS96830.1 - 3.4e-21 75.6 0.0 6e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology TUG-UBL1 PF11470.8 KXS96830.1 - 0.00071 19.8 0.2 0.0016 18.6 0.0 1.7 2 0 0 2 2 2 1 TUG ubiquitin-like domain PBP1_TM PF14812.6 KXS96830.1 - 0.042 14.2 14.4 0.71 10.3 2.6 3.6 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal UBA PF00627.31 KXS96831.1 - 0.17 11.8 0.0 0.43 10.5 0.0 1.6 1 0 0 1 1 1 0 UBA/TS-N domain Y_phosphatase3 PF13350.6 KXS96834.1 - 8.5e-53 179.7 0.0 9.6e-53 179.5 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 KXS96834.1 - 1.1e-05 25.1 0.0 2.2e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KXS96834.1 - 0.00019 21.1 0.0 0.00052 19.7 0.0 1.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Myotub-related PF06602.14 KXS96834.1 - 0.068 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain DSPc PF00782.20 KXS96834.1 - 0.089 12.6 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Peptidase_M43 PF05572.13 KXS96836.1 - 5.8e-14 52.3 0.0 7.7e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_4 PF13583.6 KXS96836.1 - 5.9e-05 22.8 0.0 8.9e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KXS96836.1 - 0.0024 17.7 0.0 0.0029 17.5 0.0 1.2 1 0 0 1 1 1 1 Matrixin Reprolysin_5 PF13688.6 KXS96836.1 - 0.021 15.0 0.0 0.021 15.0 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 DUF4953 PF16313.5 KXS96836.1 - 0.045 13.0 0.1 0.07 12.3 0.1 1.2 1 0 0 1 1 1 0 Met-zincin Reprolysin_3 PF13582.6 KXS96836.1 - 0.054 14.0 0.0 0.065 13.7 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Metallopep PF12044.8 KXS96836.1 - 0.22 10.1 0.4 0.29 9.7 0.4 1.1 1 0 0 1 1 1 0 Putative peptidase family Astacin PF01400.24 KXS96836.1 - 0.37 10.4 0.9 0.61 9.7 0.9 1.2 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Lipase_GDSL_2 PF13472.6 KXS96837.1 - 6.5e-11 43.0 0.0 2.3e-10 41.2 0.0 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Glyco_hydro_17 PF00332.18 KXS96837.1 - 2.7e-10 40.4 5.1 1.7e-08 34.5 2.8 3.0 2 1 0 2 2 2 1 Glycosyl hydrolases family 17 Lipase_GDSL PF00657.22 KXS96837.1 - 1.1e-07 32.1 0.0 2.7e-07 30.8 0.0 1.7 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase NAD_binding_8 PF13450.6 KXS96838.1 - 8.6e-13 48.3 0.2 2.3e-12 46.9 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXS96838.1 - 2e-08 34.2 2.5 3.8e-06 26.7 0.1 2.6 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXS96838.1 - 5e-08 32.5 0.2 0.00012 21.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KXS96838.1 - 5.1e-07 29.3 0.0 0.00066 19.1 0.0 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 KXS96838.1 - 1.6e-05 24.2 0.0 2.5e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KXS96838.1 - 1.9e-05 23.5 0.2 0.0073 15.0 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 KXS96838.1 - 2.2e-05 24.9 0.5 0.38 11.3 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXS96838.1 - 7.5e-05 22.8 0.0 0.0011 18.9 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 KXS96838.1 - 0.001 18.4 0.0 0.0019 17.5 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KXS96838.1 - 0.0049 16.0 0.0 0.0083 15.2 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KXS96838.1 - 0.01 15.1 0.0 0.17 11.1 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXS96838.1 - 0.012 14.9 0.0 0.085 12.1 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain Shikimate_DH PF01488.20 KXS96838.1 - 0.018 15.1 0.0 0.037 14.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 KXS96838.1 - 0.072 12.4 0.0 0.98 8.7 0.0 2.2 2 0 0 2 2 2 0 ThiF family HycI PF01750.18 KXS96838.1 - 0.073 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Hydrogenase maturation protease AlaDh_PNT_C PF01262.21 KXS96838.1 - 0.083 12.2 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 KXS96838.1 - 0.093 13.2 0.6 0.66 10.4 0.0 2.3 2 1 0 2 2 2 0 Putative NAD(P)-binding DnaJ PF00226.31 KXS96839.1 - 1.4e-18 66.7 0.7 2e-18 66.2 0.7 1.2 1 0 0 1 1 1 1 DnaJ domain LsmAD PF06741.13 KXS96840.1 - 1.6e-26 92.7 5.3 1.6e-26 92.7 5.3 2.4 3 0 0 3 3 3 1 LsmAD domain SM-ATX PF14438.6 KXS96840.1 - 1.6e-11 44.1 0.0 4.4e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 Ataxin 2 SM domain MCM3AP_GANP PF16769.5 KXS96840.1 - 1 7.6 11.5 1.8 6.8 11.5 1.3 1 0 0 1 1 1 0 MCM3AP domain of GANP DUF1013 PF06242.11 KXS96841.1 - 0.12 12.4 0.4 0.19 11.7 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1013) Spore_YhaL PF14147.6 KXS96841.1 - 5.7 6.7 10.4 0.63 9.8 0.4 2.5 2 1 1 3 3 3 0 Sporulation protein YhaL NUDIX PF00293.28 KXS96842.1 - 4.4e-14 52.7 0.1 1.4e-13 51.1 0.1 1.7 2 0 0 2 2 2 1 NUDIX domain NUDIX-like PF09296.11 KXS96842.1 - 4e-09 37.0 0.0 1e-08 35.7 0.0 1.7 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 KXS96842.1 - 4.9e-07 29.3 1.5 1.1e-06 28.2 1.5 1.6 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Pet191_N PF10203.9 KXS96843.1 - 2.5e-28 98.1 1.7 3.2e-28 97.8 1.7 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 NDUF_B7 PF05676.13 KXS96843.1 - 0.012 15.3 0.4 0.11 12.2 0.0 2.1 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) COBRA PF04833.15 KXS96843.1 - 0.014 15.3 0.6 0.018 14.9 0.6 1.1 1 0 0 1 1 1 0 COBRA-like protein PAN_3 PF08277.12 KXS96843.1 - 0.14 11.9 0.4 0.23 11.3 0.4 1.3 1 0 0 1 1 1 0 PAN-like domain CX9C PF16860.5 KXS96843.1 - 0.44 10.6 7.0 3.4 7.8 0.5 3.1 2 1 1 3 3 3 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Glyco_hydro_88 PF07470.13 KXS96844.1 - 1.9e-34 119.3 0.0 2.3e-34 119.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Tctex-1 PF03645.13 KXS96846.1 - 4.5e-37 126.4 0.1 5.1e-37 126.2 0.1 1.0 1 0 0 1 1 1 1 Tctex-1 family PRCC PF10253.9 KXS96847.1 - 1.9e-25 90.9 24.4 1.8e-22 81.2 24.4 2.6 1 1 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting FMO-like PF00743.19 KXS96848.1 - 1.4e-18 66.6 0.9 1.8e-17 63.0 0.4 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KXS96848.1 - 4.8e-08 32.5 0.2 0.00011 21.5 0.0 3.7 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KXS96848.1 - 6.2e-08 32.2 0.0 6.1e-07 29.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXS96848.1 - 2e-06 27.3 1.6 2.8e-05 23.5 0.1 3.1 3 1 1 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXS96848.1 - 4.8e-06 26.7 0.1 3.4e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Mqo PF06039.15 KXS96848.1 - 0.0055 15.3 0.0 0.1 11.1 0.0 2.2 2 0 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) NAD_binding_9 PF13454.6 KXS96848.1 - 0.0056 16.7 0.1 0.38 10.7 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 KXS96848.1 - 0.12 11.6 0.0 9.9 5.3 0.0 2.3 2 0 0 2 2 2 0 Thi4 family Malic_M PF03949.15 KXS96848.1 - 0.24 10.6 0.0 1.1 8.4 0.0 1.9 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain CNH PF00780.22 KXS96851.1 - 8.4e-75 251.9 0.0 1.3e-74 251.3 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 KXS96851.1 - 1.1e-35 123.6 0.4 2.4e-35 122.4 0.4 1.7 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 KXS96851.1 - 1e-11 45.0 0.0 6.8e-11 42.4 0.0 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KXS96851.1 - 0.05 14.1 0.0 1.2 9.6 0.0 2.8 3 0 0 3 3 3 0 PH domain PH_16 PF17838.1 KXS96851.1 - 0.1 12.5 0.1 4.6 7.1 0.0 2.4 2 0 0 2 2 2 0 PH domain Methyltransf_23 PF13489.6 KXS96852.1 - 2.2e-19 69.9 0.0 3.2e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS96852.1 - 2.6e-11 44.1 0.0 6.5e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS96852.1 - 2e-09 37.4 0.0 1.7e-08 34.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS96852.1 - 1.8e-08 35.0 0.0 8.1e-08 32.9 0.0 2.2 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS96852.1 - 1.2e-06 29.1 0.0 2.8e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXS96852.1 - 3.3e-05 23.5 0.0 7.6e-05 22.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 KXS96852.1 - 0.0059 16.7 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 KXS96852.1 - 0.014 15.1 0.0 0.023 14.5 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_4 PF02390.17 KXS96852.1 - 0.015 14.8 0.0 0.03 13.8 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.13 KXS96852.1 - 0.019 14.4 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 KXS96852.1 - 0.046 13.1 0.0 0.19 11.1 0.0 1.9 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Alg14 PF08660.11 KXS96853.1 - 7e-52 175.9 0.0 1.6e-51 174.8 0.0 1.6 1 1 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like AIP3 PF03915.13 KXS96855.1 - 5.1e-163 542.9 10.1 5.1e-163 542.9 10.1 1.5 2 0 0 2 2 2 1 Actin interacting protein 3 HsbA PF12296.8 KXS96855.1 - 0.042 14.3 3.9 7.3 7.0 0.0 4.4 5 1 2 7 7 7 0 Hydrophobic surface binding protein A RMMBL PF07521.12 KXS96855.1 - 0.11 12.4 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain NPV_P10 PF05531.12 KXS96855.1 - 0.24 11.9 6.0 0.66 10.5 0.5 3.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 KXS96855.1 - 1.6 8.8 7.3 9.7 6.3 0.3 3.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) AA_permease PF00324.21 KXS96856.1 - 7.2e-125 417.3 36.3 9.7e-125 416.8 36.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXS96856.1 - 2.8e-37 128.6 40.6 4.3e-37 127.9 40.6 1.2 1 1 0 1 1 1 1 Amino acid permease Aa_trans PF01490.18 KXS96857.1 - 1.3e-99 333.8 15.5 1.3e-99 333.8 15.5 1.3 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein Abhydrolase_9_N PF15420.6 KXS96857.1 - 0.0067 16.5 1.2 0.0067 16.5 1.2 3.1 3 1 1 4 4 4 1 Alpha/beta-hydrolase family N-terminus Trp_Tyr_perm PF03222.13 KXS96857.1 - 0.36 9.8 24.9 0.038 13.0 19.9 1.9 2 0 0 2 2 2 0 Tryptophan/tyrosine permease family Abhydro_lipase PF04083.16 KXS96858.1 - 1.3e-22 79.2 0.1 2.4e-22 78.2 0.1 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 KXS96858.1 - 3e-21 76.2 0.7 8.4e-21 74.8 0.1 2.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXS96858.1 - 0.00015 21.2 0.0 0.015 14.6 0.0 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 KXS96858.1 - 0.00073 19.3 0.0 0.44 10.2 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Prenyltrans PF00432.21 KXS96859.1 - 2.4e-31 107.1 15.5 9.5e-09 34.9 0.4 5.4 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Pyr_redox_2 PF07992.14 KXS96860.1 - 5e-10 39.1 0.0 3e-05 23.4 0.0 2.9 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KXS96860.1 - 8.6e-10 37.6 0.0 3.2e-07 29.2 0.0 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXS96860.1 - 8e-08 31.9 0.1 3.3e-05 23.3 0.0 3.1 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXS96860.1 - 4.3e-06 26.1 0.0 0.00029 20.1 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KXS96860.1 - 0.00023 21.3 0.0 0.00068 19.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 KXS96860.1 - 0.00043 20.4 0.3 0.91 9.6 0.0 2.8 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 KXS96860.1 - 0.03 13.9 0.7 4.4 6.8 0.2 3.2 3 1 0 3 3 3 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXS96860.1 - 0.04 13.0 0.1 0.067 12.3 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 KXS96860.1 - 0.16 12.6 0.2 4 8.1 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase V_ATPase_I PF01496.19 KXS96861.1 - 0 1066.4 0.0 0 1066.3 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family CheZ PF04344.13 KXS96861.1 - 0.0004 20.4 1.4 0.0011 18.9 0.5 1.9 2 0 0 2 2 2 1 Chemotaxis phosphatase, CheZ Filament PF00038.21 KXS96861.1 - 0.011 15.4 4.7 0.11 12.1 1.0 2.1 2 0 0 2 2 2 0 Intermediate filament protein Serine_rich PF08824.10 KXS96861.1 - 0.021 14.9 1.7 0.026 14.5 0.3 1.8 2 0 0 2 2 2 0 Serine rich protein interaction domain Baculo_PEP_C PF04513.12 KXS96861.1 - 0.043 13.9 0.7 12 5.9 0.0 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Suppressor_APC PF11414.8 KXS96861.1 - 0.057 13.5 1.4 9.2 6.4 0.0 2.5 2 0 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein HWE_HK PF07536.14 KXS96861.1 - 0.068 13.9 1.6 0.53 11.0 0.1 2.6 2 0 0 2 2 2 0 HWE histidine kinase DUF1664 PF07889.12 KXS96861.1 - 0.092 12.8 2.9 11 6.1 0.1 2.9 2 2 0 2 2 2 0 Protein of unknown function (DUF1664) DUF1515 PF07439.11 KXS96861.1 - 0.1 12.6 0.1 0.34 10.9 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) DUF16 PF01519.16 KXS96861.1 - 0.24 11.9 4.8 1.2 9.7 0.2 3.0 3 1 0 3 3 3 0 Protein of unknown function DUF16 FapA PF03961.13 KXS96861.1 - 0.57 8.7 3.9 0.14 10.8 0.3 1.6 2 0 0 2 2 2 0 Flagellar Assembly Protein A CorA PF01544.18 KXS96861.1 - 0.59 9.4 5.1 0.68 9.2 1.3 2.3 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Rab5-bind PF09311.11 KXS96861.1 - 0.62 9.4 4.1 0.31 10.4 1.4 1.7 2 0 0 2 2 2 0 Rabaptin-like protein MerR-DNA-bind PF09278.11 KXS96861.1 - 2 9.0 5.2 0.59 10.7 0.4 2.6 3 0 0 3 3 3 0 MerR, DNA binding DUF3450 PF11932.8 KXS96861.1 - 2.2 7.5 6.3 0.45 9.8 1.7 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) DASH_Dam1 PF08653.10 KXS96861.1 - 4 7.3 5.8 5.7 6.8 0.2 3.9 5 0 0 5 5 4 0 DASH complex subunit Dam1 HMMR_N PF15905.5 KXS96861.1 - 4.8 6.6 7.1 25 4.2 0.2 2.3 2 1 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Fib_alpha PF08702.10 KXS96861.1 - 6.7 6.9 5.3 2.2 8.4 1.2 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DHR10 PF18595.1 KXS96861.1 - 8.4 6.5 8.3 14 5.8 5.3 2.4 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain MFS_1 PF07690.16 KXS96862.1 - 9.8e-22 77.3 32.3 9.8e-22 77.3 32.3 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS96862.1 - 4.8e-13 48.8 23.0 6.6e-11 41.7 6.3 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter Dynactin_p22 PF07426.11 KXS96863.1 - 6.7e-11 42.3 0.8 7.9e-11 42.1 0.8 1.1 1 0 0 1 1 1 1 Dynactin subunit p22 XhlA PF10779.9 KXS96863.1 - 0.13 12.5 0.3 9.8 6.5 0.1 2.6 2 0 0 2 2 2 0 Haemolysin XhlA SlyX PF04102.12 KXS96863.1 - 3.6 8.3 8.2 13 6.5 3.9 3.4 3 1 0 3 3 3 0 SlyX His_Phos_2 PF00328.22 KXS96864.1 - 0.02 14.3 0.0 0.47 9.7 0.0 2.2 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 2) OCIA PF07051.11 KXS96864.1 - 0.18 11.9 0.7 18 5.4 0.0 3.4 4 0 0 4 4 4 0 Ovarian carcinoma immunoreactive antigen (OCIA) DUF202 PF02656.15 KXS96866.1 - 2e-14 53.8 4.4 2e-14 53.8 4.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF5337 PF17272.2 KXS96866.1 - 2.2 8.2 10.7 0.35 10.7 6.1 2.2 2 1 0 2 2 2 0 Family of unknown function (DUF5337) YscO PF07321.12 KXS96867.1 - 0.23 11.4 7.7 1.2 9.1 7.4 1.9 1 1 0 1 1 1 0 Type III secretion protein YscO Sec1 PF00995.23 KXS96872.1 - 9.2e-116 388.4 0.0 1.1e-115 388.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family SRF-TF PF00319.18 KXS96873.1 - 6.4e-24 83.2 0.1 9.5e-24 82.6 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) ubiquitin PF00240.23 KXS96874.1 - 1.7e-11 43.7 0.0 2.5e-06 27.2 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 KXS96874.1 - 0.014 15.2 0.0 4.1 7.3 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Xpo1 PF08389.12 KXS96875.1 - 6.3e-27 94.5 5.3 3.8e-26 91.9 0.4 3.7 3 1 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 KXS96875.1 - 4.7e-07 29.6 0.3 2.1e-06 27.6 0.1 2.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 KXS96875.1 - 0.00047 20.5 0.0 0.016 15.6 0.0 3.3 2 0 0 2 2 2 1 HEAT repeats HEAT_EZ PF13513.6 KXS96875.1 - 0.0024 18.3 2.6 0.014 15.9 0.0 3.8 4 1 1 5 5 5 1 HEAT-like repeat Adaptin_N PF01602.20 KXS96875.1 - 0.011 14.4 1.4 0.37 9.3 0.3 2.3 2 0 0 2 2 2 0 Adaptin N terminal region HEAT PF02985.22 KXS96875.1 - 0.038 14.3 0.0 41 4.8 0.0 4.4 2 0 0 2 2 2 0 HEAT repeat Importin_rep_3 PF18806.1 KXS96875.1 - 0.16 12.0 0.4 1.7 8.8 0.0 2.9 3 0 0 3 3 3 0 Importin 13 repeat PX PF00787.24 KXS96876.1 - 2.9e-21 75.5 0.0 4.8e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 PX domain MFS_1 PF07690.16 KXS96878.1 - 7e-45 153.5 52.4 5.3e-44 150.6 53.5 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXS96878.1 - 3.6e-21 75.3 24.4 4.9e-21 74.8 24.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXS96878.1 - 4.5e-17 62.1 5.1 4.5e-17 62.1 5.1 3.7 3 1 0 4 4 4 2 Sugar (and other) transporter DUF4448 PF14610.6 KXS96878.1 - 0.072 12.9 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) PHC2_SAM_assoc PF16616.5 KXS96878.1 - 2 9.3 8.5 0.74 10.6 5.8 1.6 2 0 0 2 2 2 0 Unstructured region on Polyhomeotic-like protein 1 and 2 Taxilin PF09728.9 KXS96879.1 - 0.019 14.2 2.3 0.03 13.5 2.3 1.2 1 0 0 1 1 1 0 Myosin-like coiled-coil protein SAP30_Sin3_bdg PF13867.6 KXS96880.1 - 0.065 13.6 0.1 0.24 11.8 0.1 1.9 2 0 0 2 2 2 0 Sin3 binding region of histone deacetylase complex subunit SAP30 p450 PF00067.22 KXS96881.1 - 6.7e-07 28.4 0.0 1.5e-06 27.3 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KXS96882.1 - 8.5e-07 28.1 0.0 1.9e-06 26.9 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KXS96883.1 - 6.6e-07 28.4 0.0 1.4e-06 27.3 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 K_oxygenase PF13434.6 KXS96884.1 - 1.4e-16 60.5 0.0 3.1e-15 56.1 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KXS96884.1 - 6.1e-16 58.5 0.0 5e-15 55.6 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KXS96884.1 - 5.6e-15 54.8 0.0 1.8e-14 53.1 0.0 1.7 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KXS96884.1 - 2.1e-11 43.6 0.0 1.2e-10 41.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXS96884.1 - 0.00028 20.6 2.2 0.034 13.7 0.0 3.6 3 1 0 4 4 4 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXS96884.1 - 0.00077 19.6 0.2 0.0027 17.9 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXS96884.1 - 0.0017 17.7 0.2 0.35 10.1 0.0 2.2 2 0 0 2 2 2 2 Thi4 family Lycopene_cycl PF05834.12 KXS96884.1 - 0.012 14.7 0.2 0.29 10.1 0.0 2.6 2 1 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 KXS96884.1 - 0.014 15.4 0.1 0.4 10.6 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 KXS96884.1 - 0.025 13.9 0.9 3.5 6.9 0.1 2.6 2 1 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXS96884.1 - 0.16 12.6 1.1 39 4.9 0.0 3.2 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase tRNA-synt_His PF13393.6 KXS96885.1 - 1e-39 136.7 0.0 1.9e-33 116.1 0.0 2.2 2 0 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 KXS96885.1 - 3.3e-10 40.0 0.0 6.4e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 KXS96885.1 - 2.5e-05 23.9 0.0 5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs tRNA-synt_2b PF00587.25 KXS96885.1 - 0.00024 21.1 0.0 0.0008 19.4 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.20 KXS96885.1 - 0.0019 17.3 0.0 0.014 14.5 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) Zn_clus PF00172.18 KXS96887.1 - 5.2e-06 26.5 11.8 1.1e-05 25.4 11.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Torus PF16131.5 KXS96889.1 - 0.025 15.3 8.4 0.21 12.3 0.3 3.4 2 1 0 3 3 3 0 Torus domain BTB PF00651.31 KXS96891.1 - 2.8e-11 43.6 0.0 3.8e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Amidase PF01425.21 KXS96893.1 - 2.6e-20 72.8 0.0 3.2e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 Amidase Amidase PF01425.21 KXS96894.1 - 2.5e-47 161.9 0.2 1.3e-46 159.6 0.2 2.1 1 1 0 1 1 1 1 Amidase Rh5 PF18515.1 KXS96896.1 - 0.08 12.2 0.6 0.13 11.6 0.6 1.3 1 0 0 1 1 1 0 Rh5 coiled-coil domain Bcr-Abl_Oligo PF09036.10 KXS96896.1 - 0.16 12.0 0.3 0.38 10.8 0.3 1.6 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain DUF1451 PF07295.11 KXS96896.1 - 0.53 10.3 7.2 2.6 8.1 0.4 2.4 2 0 0 2 2 2 0 Zinc-ribbon containing domain Spore_II_R PF09551.10 KXS96896.1 - 1.4 9.4 4.0 1.6 9.2 0.7 2.5 3 0 0 3 3 3 0 Stage II sporulation protein R (spore_II_R) DUF4795 PF16043.5 KXS96896.1 - 1.6 8.3 7.5 0.46 10.1 3.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) KxDL PF10241.9 KXS96896.1 - 2.1 8.7 5.9 1.4 9.2 2.8 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein MIP-T3_C PF17749.1 KXS96896.1 - 2.6 8.0 9.3 0.3 11.0 2.2 2.2 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region DUF4618 PF15397.6 KXS96896.1 - 3 7.2 12.8 1.2 8.5 4.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) Filament PF00038.21 KXS96896.1 - 4.4 6.8 11.4 0.19 11.3 4.9 1.9 2 0 0 2 2 2 0 Intermediate filament protein DUF2408 PF10303.9 KXS96896.1 - 6.2 7.4 6.9 6.3 7.4 2.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) tRNA-synt_1 PF00133.22 KXS96898.1 - 3.4e-218 725.8 0.6 7.4e-217 721.4 0.6 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KXS96898.1 - 6.9e-31 107.3 0.0 3.9e-30 104.8 0.0 2.2 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KXS96898.1 - 1.4e-14 53.7 0.5 9.9e-07 27.8 0.0 4.9 3 2 1 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 KXS96898.1 - 1.4e-07 31.2 12.2 5.9e-07 29.2 0.0 3.5 3 1 1 4 4 4 2 Leucyl-tRNA synthetase, Domain 2 PepSY PF03413.19 KXS96898.1 - 0.095 13.3 0.0 0.095 13.3 0.0 3.1 2 1 0 2 2 2 0 Peptidase propeptide and YPEB domain tRNA-synt_1e PF01406.19 KXS96898.1 - 0.13 11.5 4.2 0.42 9.9 0.0 2.8 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain DUF4770 PF15994.5 KXS96898.1 - 6.2 7.0 8.6 14 5.8 8.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) 5-FTHF_cyc-lig PF01812.20 KXS96899.1 - 4e-35 121.4 0.0 1e-34 120.1 0.0 1.6 1 1 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Rot1 PF10681.9 KXS96900.1 - 8.1e-97 322.8 0.1 9.4e-97 322.6 0.1 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal Lipocalin_4 PF13648.6 KXS96900.1 - 0.014 16.3 1.5 0.067 14.2 1.5 2.1 1 1 1 2 2 2 0 Lipocalin-like domain Rot1 PF10681.9 KXS96901.1 - 8.1e-97 322.8 0.1 9.4e-97 322.6 0.1 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal Lipocalin_4 PF13648.6 KXS96901.1 - 0.014 16.3 1.5 0.067 14.2 1.5 2.1 1 1 1 2 2 2 0 Lipocalin-like domain Rot1 PF10681.9 KXS96902.1 - 8.1e-97 322.8 0.1 9.4e-97 322.6 0.1 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal Lipocalin_4 PF13648.6 KXS96902.1 - 0.014 16.3 1.5 0.067 14.2 1.5 2.1 1 1 1 2 2 2 0 Lipocalin-like domain POT1PC PF16686.5 KXS96904.1 - 0.032 14.1 0.2 3.9 7.3 0.0 2.2 2 0 0 2 2 2 0 ssDNA-binding domain of telomere protection protein Chalcone_3 PF16036.5 KXS96904.1 - 0.12 12.5 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Chalcone isomerase-like CAP_N PF01213.19 KXS96912.1 - 1 8.8 3.2 16 4.8 0.6 2.1 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal DUF4734 PF15881.5 KXS96916.1 - 0.13 12.4 1.2 0.29 11.3 0.3 2.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4734) RACo_linker PF17650.1 KXS96918.1 - 0.079 12.8 0.4 0.36 10.7 0.0 2.3 3 0 0 3 3 3 0 RACo linker region US2 PF02476.15 KXS96918.1 - 1.2 9.9 4.5 2.8 8.6 0.2 2.7 3 0 0 3 3 3 0 US2 family Trypan_PARP PF05887.11 KXS96918.1 - 1.9 8.5 27.2 0.38 10.7 11.7 2.3 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) Adeno_E1A PF02703.14 KXS96918.1 - 8.1 5.9 10.6 1.3 8.5 2.6 2.4 3 0 0 3 3 3 0 Early E1A protein ArgoMid PF16487.5 KXS96920.1 - 0.061 13.6 0.0 0.19 12.0 0.0 1.9 1 1 0 1 1 1 0 Mid domain of argonaute Laminin_B PF00052.18 KXS96920.1 - 0.64 9.9 4.4 0.22 11.4 0.9 1.9 2 0 0 2 2 2 0 Laminin B (Domain IV) CK2S PF15011.6 KXS96932.1 - 0.0013 18.6 0.2 0.0032 17.4 0.2 1.6 1 0 0 1 1 1 1 Casein Kinase 2 substrate HSBP1 PF06825.12 KXS96932.1 - 0.009 15.8 0.6 0.016 15.0 0.6 1.4 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Synaptonemal_3 PF15191.6 KXS96932.1 - 0.051 13.4 0.0 0.67 9.8 0.0 2.3 2 0 0 2 2 2 0 Synaptonemal complex central element protein 3 Tho2 PF11262.8 KXS96932.1 - 0.051 12.8 0.1 0.07 12.3 0.1 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Adaptin_N PF01602.20 KXS96932.1 - 0.11 11.0 0.0 0.17 10.4 0.0 1.2 1 0 0 1 1 1 0 Adaptin N terminal region 7TMR-HDED PF07697.11 KXS96932.1 - 0.26 11.4 0.8 0.38 10.9 0.8 1.2 1 0 0 1 1 1 0 7TM-HD extracellular TPR_MLP1_2 PF07926.12 KXS96933.1 - 3.2 7.8 7.1 12 6.0 0.6 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein NACHT_N PF17100.5 KXS96934.1 - 0.21 11.4 0.9 37 4.1 0.0 3.0 3 0 0 3 3 3 0 N-terminal domain of NWD NACHT-NTPase Cwf_Cwc_15 PF04889.12 KXS96935.1 - 0.026 14.3 8.1 0.23 11.2 4.6 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein eIF-3c_N PF05470.12 KXS96935.1 - 0.078 11.3 0.2 0.089 11.1 0.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus End3 PF12761.7 KXS96935.1 - 0.69 10.1 5.7 0.29 11.3 2.2 1.8 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 SOG2 PF10428.9 KXS96936.1 - 1.7 7.7 19.7 2.9 7.0 19.0 1.6 2 0 0 2 2 2 0 RAM signalling pathway protein CAP_N PF01213.19 KXS96936.1 - 1.9 7.9 18.4 0.17 11.3 7.1 2.4 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal NPV_P10 PF05531.12 KXS96940.1 - 2.7 8.5 4.9 4.4 7.8 0.1 3.4 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein DASH_Dam1 PF08653.10 KXS96940.1 - 4.3 7.2 4.7 6.1 6.7 0.0 3.1 3 0 0 3 3 3 0 DASH complex subunit Dam1 Vir_act_alpha_C PF10400.9 KXS96943.1 - 0.032 14.9 0.3 0.046 14.4 0.3 1.3 1 0 0 1 1 1 0 Virulence activator alpha C-term UL42 PF17638.2 KXS96947.1 - 0.21 11.6 5.9 0.94 9.5 5.9 2.1 1 0 0 1 1 1 0 HCMV UL42 COP-gamma_platf PF08752.10 KXS96951.1 - 0.14 12.3 0.1 0.2 11.8 0.1 1.3 1 1 0 1 1 1 0 Coatomer gamma subunit appendage platform subdomain Cut8 PF08559.10 KXS96962.1 - 1.3e-77 260.7 0.0 1.5e-77 260.5 0.0 1.0 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein Pyr_redox_2 PF07992.14 KXS96963.1 - 4.3e-63 213.3 0.2 5.9e-63 212.8 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KXS96963.1 - 2.3e-32 111.5 0.5 1.2e-31 109.2 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KXS96963.1 - 2.1e-17 63.4 1.3 6.5e-17 61.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXS96963.1 - 1.4e-15 57.3 0.4 2.5e-15 56.6 0.4 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KXS96963.1 - 9.2e-05 21.8 0.2 0.17 11.1 0.2 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.6 KXS96963.1 - 0.00012 21.3 0.0 0.00019 20.7 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.18 KXS96963.1 - 0.012 15.6 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 KXS96963.1 - 0.038 13.3 0.0 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 KXS96963.1 - 0.046 12.8 0.2 0.59 9.2 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KXS96963.1 - 1.1 8.3 4.7 2.7 7.0 1.6 2.6 3 0 0 3 3 3 0 FAD binding domain Complex1_51K PF01512.17 KXS96964.1 - 2.6e-46 157.3 0.0 4.2e-46 156.6 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 KXS96964.1 - 2.9e-29 101.0 0.3 5.9e-29 100.0 0.3 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 KXS96964.1 - 3.7e-09 36.3 0.0 9.5e-09 35.0 0.0 1.8 1 0 0 1 1 1 1 SLBB domain Ribonuc_red_lgC PF02867.15 KXS96965.1 - 3.2e-189 629.8 0.0 4.5e-189 629.4 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 KXS96965.1 - 2.3e-24 85.2 0.1 5.4e-24 84.0 0.1 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 KXS96965.1 - 4.5e-16 59.2 0.0 1.3e-15 57.7 0.0 1.9 1 0 0 1 1 1 1 ATP cone domain FxsA PF04186.13 KXS96966.1 - 0.014 15.5 0.2 0.016 15.3 0.2 1.1 1 0 0 1 1 1 0 FxsA cytoplasmic membrane protein SNARE_assoc PF09335.11 KXS96966.1 - 0.014 15.8 0.0 0.017 15.6 0.0 1.1 1 0 0 1 1 1 0 SNARE associated Golgi protein Tcf25 PF04910.14 KXS96967.1 - 3.1e-76 256.7 0.2 4.1e-76 256.3 0.2 1.1 1 0 0 1 1 1 1 Transcriptional repressor TCF25 Nop53 PF07767.11 KXS96967.1 - 0.8 9.0 22.1 1.9 7.8 22.1 1.5 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Peptidase_M24 PF00557.24 KXS96968.1 - 8.3e-45 153.0 0.4 1.2e-44 152.6 0.4 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Pectinesterase PF01095.19 KXS96968.1 - 0.0052 15.5 0.0 0.0085 14.8 0.0 1.2 1 0 0 1 1 1 1 Pectinesterase YL1 PF05764.13 KXS96968.1 - 0.03 14.4 6.0 0.048 13.8 6.0 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Ribosomal_L37 PF08561.10 KXS96968.1 - 0.052 14.1 1.9 0.1 13.2 1.9 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 Med3 PF11593.8 KXS96968.1 - 0.65 9.1 3.2 1 8.5 3.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CDC45 PF02724.14 KXS96968.1 - 6.4 4.9 7.5 9.2 4.4 7.5 1.1 1 0 0 1 1 1 0 CDC45-like protein PGA2 PF07543.12 KXS96968.1 - 7.7 6.5 9.0 1.2 9.1 4.6 1.9 2 0 0 2 2 2 0 Protein trafficking PGA2 RSB_motif PF16294.5 KXS96968.1 - 9.8 6.5 8.7 0.3 11.4 2.0 1.8 2 0 0 2 2 2 0 RNSP1-SAP18 binding (RSB) motif MBOAT_2 PF13813.6 KXS96969.1 - 1.5e-18 66.9 6.2 1.5e-18 66.9 6.2 2.2 3 0 0 3 3 3 1 Membrane bound O-acyl transferase family Peptidase_C93 PF06035.11 KXS96970.1 - 0.0051 16.6 1.0 0.012 15.4 1.0 1.5 1 0 0 1 1 1 1 Bacterial transglutaminase-like cysteine proteinase BTLCP ATG2_CAD PF13329.6 KXS96970.1 - 0.12 12.1 1.1 0.21 11.3 1.1 1.3 1 0 0 1 1 1 0 Autophagy-related protein 2 CAD motif FAM76 PF16046.5 KXS96970.1 - 0.15 11.4 0.1 0.22 10.8 0.1 1.2 1 0 0 1 1 1 0 FAM76 protein Macoilin PF09726.9 KXS96970.1 - 8 4.9 6.3 10 4.5 6.3 1.1 1 0 0 1 1 1 0 Macoilin family DUF1100 PF06500.11 KXS96971.1 - 3.1e-14 52.6 0.0 4.1e-14 52.2 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S9 PF00326.21 KXS96971.1 - 4.2e-07 29.6 0.0 1.8e-06 27.6 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KXS96971.1 - 2.7e-06 27.2 0.0 4.2e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 KXS96971.1 - 0.0021 17.8 0.0 1.1 8.8 0.1 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Esterase PF00756.20 KXS96971.1 - 0.015 15.0 0.0 0.085 12.5 0.0 2.0 1 1 0 1 1 1 0 Putative esterase Abhydrolase_6 PF12697.7 KXS96971.1 - 0.023 15.3 0.0 0.036 14.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family BAAT_C PF08840.11 KXS96971.1 - 0.031 14.2 0.0 0.063 13.2 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 KXS96971.1 - 0.046 13.0 0.1 0.76 9.0 0.2 2.1 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KXS96971.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold MIT PF04212.18 KXS96971.1 - 0.24 11.5 1.7 0.49 10.5 1.7 1.6 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain EamA PF00892.20 KXS96972.1 - 2.3e-10 40.8 35.7 1.6e-07 31.6 4.9 2.8 3 1 0 3 3 3 2 EamA-like transporter family CSG2 PF16965.5 KXS96972.1 - 9.5e-05 21.5 12.7 0.00022 20.3 4.7 2.1 2 0 0 2 2 2 2 Ceramide synthase regulator Nuc_sug_transp PF04142.15 KXS96972.1 - 0.00044 19.5 9.9 0.00083 18.6 9.9 1.4 1 1 0 1 1 1 1 Nucleotide-sugar transporter Usp PF00582.26 KXS96974.1 - 1.5e-19 70.9 0.5 8.7e-14 52.2 0.1 2.7 2 0 0 2 2 2 2 Universal stress protein family WD40 PF00400.32 KXS96974.1 - 1.5e-16 60.4 6.1 2e-06 28.4 0.4 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS96974.1 - 9.7e-10 38.6 2.5 0.025 14.9 0.0 4.5 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KXS96974.1 - 0.15 10.6 0.1 2 6.9 0.0 2.0 1 1 1 2 2 2 0 Cytochrome D1 heme domain Usp PF00582.26 KXS96976.1 - 1.5e-19 70.9 0.5 8.7e-14 52.2 0.1 2.7 2 0 0 2 2 2 2 Universal stress protein family WD40 PF00400.32 KXS96976.1 - 1.5e-16 60.4 6.1 2e-06 28.4 0.4 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS96976.1 - 9.7e-10 38.6 2.5 0.025 14.9 0.0 4.5 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KXS96976.1 - 0.15 10.6 0.1 2 6.9 0.0 2.0 1 1 1 2 2 2 0 Cytochrome D1 heme domain AIM5 PF17050.5 KXS96977.1 - 1e-16 61.5 1.1 1.4e-16 61.0 1.1 1.2 1 0 0 1 1 1 1 Altered inheritance of mitochondria 5 Dscam_C PF12355.8 KXS96977.1 - 0.053 14.5 0.1 0.072 14.0 0.1 1.3 1 1 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal PNK3P PF08645.11 KXS96978.1 - 2.5e-58 196.3 0.1 5.9e-58 195.1 0.1 1.7 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase SUR7 PF06687.12 KXS96978.1 - 6.1e-37 127.3 20.6 9.1e-37 126.7 20.6 1.3 1 0 0 1 1 1 1 SUR7/PalI family AAA_33 PF13671.6 KXS96978.1 - 7e-23 81.4 0.0 1.6e-20 73.8 0.0 2.5 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 KXS96978.1 - 0.00017 21.1 0.1 0.016 14.7 0.0 2.3 1 1 1 2 2 2 1 Chromatin associated protein KTI12 PatG_C PF18065.1 KXS96978.1 - 0.037 14.0 0.1 0.37 10.8 0.0 2.4 2 0 0 2 2 2 0 PatG C-terminal RCR PF12273.8 KXS96978.1 - 0.12 13.0 0.0 0.12 13.0 0.0 2.2 3 0 0 3 3 3 0 Chitin synthesis regulation, resistance to Congo red SCIMP PF15050.6 KXS96978.1 - 0.54 10.7 3.1 1 9.8 0.1 2.5 2 0 0 2 2 2 0 SCIMP protein HET PF06985.11 KXS96979.1 - 5.6e-26 91.7 2.0 1.6e-25 90.2 2.0 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3410 PF11890.8 KXS96979.1 - 0.15 11.9 0.0 0.38 10.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3410) Ribosomal_L17 PF01196.19 KXS96981.1 - 3e-33 114.6 0.4 7.9e-33 113.2 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L17 Molybdopterin_N PF18364.1 KXS96981.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin oxidoreductase N-terminal domain MFS_1 PF07690.16 KXS96982.1 - 2.2e-35 122.3 34.4 2.9e-35 121.8 34.1 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF5592 PF17332.2 KXS96982.1 - 0.21 12.2 0.9 15 6.2 0.0 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5592) MFS_1 PF07690.16 KXS96983.1 - 3.3e-35 121.7 34.1 5.2e-35 121.0 34.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 KXS96984.1 - 3.4e-35 121.6 34.1 4.1e-35 121.4 34.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily BTP PF05232.12 KXS96984.1 - 3.1 7.9 7.4 0.72 10.0 1.9 2.5 2 0 0 2 2 2 0 Chlorhexidine efflux transporter MAD PF05557.13 KXS96985.1 - 0.00053 18.5 31.5 0.0008 17.9 31.5 1.2 1 0 0 1 1 1 1 Mitotic checkpoint protein TACC_C PF05010.14 KXS96985.1 - 0.0068 16.2 13.8 0.0068 16.2 13.8 2.4 2 0 0 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF3450 PF11932.8 KXS96985.1 - 0.029 13.7 23.3 0.048 13.0 10.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) Golgin_A5 PF09787.9 KXS96985.1 - 0.065 12.7 37.4 0.18 11.3 28.7 2.4 1 1 1 2 2 2 0 Golgin subfamily A member 5 Syntaxin-6_N PF09177.11 KXS96985.1 - 0.09 13.3 26.0 0.61 10.7 10.8 4.6 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Spc7 PF08317.11 KXS96985.1 - 0.1 11.5 41.1 0.31 9.9 7.3 3.3 2 1 2 4 4 4 0 Spc7 kinetochore protein APG6_N PF17675.1 KXS96985.1 - 0.18 12.4 49.0 0.3 11.6 11.4 3.7 3 2 0 3 3 2 0 Apg6 coiled-coil region DivIC PF04977.15 KXS96985.1 - 0.35 10.7 29.9 0.028 14.2 6.2 5.2 2 2 4 6 6 6 0 Septum formation initiator DUF4239 PF14023.6 KXS96985.1 - 1.6 8.4 5.2 0.4 10.4 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4239) Filament PF00038.21 KXS96985.1 - 1.7 8.1 30.8 2.4 7.7 29.7 1.9 1 1 0 1 1 1 0 Intermediate filament protein ATG16 PF08614.11 KXS96985.1 - 1.9 8.7 45.0 0.058 13.6 24.6 3.5 2 1 0 3 3 3 0 Autophagy protein 16 (ATG16) HAP1_N PF04849.13 KXS96985.1 - 2.6 7.2 34.3 2 7.5 7.1 2.4 2 0 0 2 2 2 0 HAP1 N-terminal conserved region Lectin_N PF03954.14 KXS96985.1 - 2.7 7.8 19.8 0.43 10.3 2.9 3.7 2 2 2 4 4 4 0 Hepatic lectin, N-terminal domain TMPIT PF07851.13 KXS96985.1 - 2.9 7.0 21.1 0.22 10.7 6.9 2.8 1 1 1 3 3 3 0 TMPIT-like protein Cnn_1N PF07989.11 KXS96985.1 - 3 8.1 34.6 0.61 10.3 5.9 5.9 2 2 3 5 5 5 0 Centrosomin N-terminal motif 1 FapA PF03961.13 KXS96985.1 - 3.2 6.2 22.6 1.5 7.4 10.4 2.6 1 1 2 3 3 3 0 Flagellar Assembly Protein A DUF1664 PF07889.12 KXS96985.1 - 3.6 7.6 18.7 2 8.5 5.8 3.5 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) SID-1_RNA_chan PF13965.6 KXS96985.1 - 4.1 5.7 5.3 1 7.7 0.3 1.9 1 1 0 2 2 2 0 dsRNA-gated channel SID-1 GldM_N PF12081.8 KXS96985.1 - 4.4 7.4 19.4 1.2 9.2 8.6 2.8 1 1 2 3 3 3 0 GldM N-terminal domain DUF19 PF01579.18 KXS96985.1 - 5.3 6.8 10.3 27 4.5 4.1 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF19) DUF2730 PF10805.8 KXS96985.1 - 5.9 7.0 15.0 0.83 9.8 0.8 3.4 3 1 2 5 5 4 0 Protein of unknown function (DUF2730) GAS PF13851.6 KXS96985.1 - 6.1 6.1 33.9 0.1 11.9 18.0 3.2 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding KASH_CCD PF14662.6 KXS96985.1 - 6.9 6.5 39.0 0.21 11.4 24.7 4.0 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH DUF4618 PF15397.6 KXS96985.1 - 7.7 5.8 27.6 1.6 8.1 9.2 3.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4618) USP8_interact PF08941.10 KXS96985.1 - 9.7 6.0 9.8 0.33 10.8 1.1 2.8 2 2 3 5 5 5 0 USP8 interacting Epimerase PF01370.21 KXS96986.1 - 3.9e-20 72.3 0.0 1.6e-19 70.3 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXS96986.1 - 3.7e-18 65.5 0.0 4.9e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KXS96986.1 - 3.3e-13 49.8 0.0 3.4e-11 43.1 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KXS96986.1 - 2.9e-11 43.0 0.0 4e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KXS96986.1 - 1.4e-06 28.3 0.0 3.8e-06 26.9 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXS96986.1 - 1.6e-06 27.9 0.0 6.8e-06 25.8 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.15 KXS96986.1 - 0.0012 18.0 0.0 0.0017 17.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein SMN PF06003.12 KXS96986.1 - 0.079 12.2 0.3 0.17 11.2 0.3 1.5 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) KR PF08659.10 KXS96986.1 - 0.098 12.6 0.2 0.54 10.2 0.2 2.0 1 1 0 1 1 1 0 KR domain preATP-grasp_3 PF18301.1 KXS96986.1 - 0.11 12.8 0.3 4.5 7.6 0.0 3.0 3 0 0 3 3 3 0 pre ATP-grasp 3 domain DUF4976 PF16347.5 KXS96987.1 - 0.21 11.9 0.5 11 6.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4976) PhyH PF05721.13 KXS96990.1 - 4.2e-17 63.1 0.0 6e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) SCP2 PF02036.17 KXS96990.1 - 0.0015 19.0 0.0 0.0034 17.9 0.0 1.6 1 1 0 1 1 1 1 SCP-2 sterol transfer family 2OG-FeII_Oxy_3 PF13640.6 KXS96990.1 - 0.025 15.4 0.0 0.055 14.4 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.6 KXS96990.1 - 0.14 12.6 0.0 0.34 11.3 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Hexapep_2 PF14602.6 KXS96992.1 - 1.3e-13 50.4 4.7 2.4e-11 43.2 1.0 2.4 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 KXS96992.1 - 3.7e-12 45.5 7.5 3.4e-09 36.1 2.0 3.4 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 KXS96992.1 - 9.2e-05 22.6 0.1 0.00015 22.0 0.1 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase DUF3328 PF11807.8 KXS96993.1 - 7.6e-27 94.5 0.3 1.2e-26 93.9 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 KXS96994.1 - 1.6e-31 109.8 1.3 2.6e-31 109.1 1.3 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Aquarius_N PF16399.5 KXS96995.1 - 4.6e-293 974.2 0.0 5.8e-293 973.9 0.0 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 KXS96995.1 - 2.8e-28 98.9 0.0 5.1e-28 98.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KXS96995.1 - 6.5e-24 85.1 0.0 2.2e-23 83.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KXS96995.1 - 3.5e-07 30.1 0.0 0.00023 21.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KXS96995.1 - 3.5e-06 27.4 0.0 1.1e-05 25.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 KXS96995.1 - 3.7e-06 27.1 0.0 1.1e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD_C_2 PF13538.6 KXS96995.1 - 0.00016 21.5 0.3 0.014 15.2 0.0 2.6 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain DnaB_C PF03796.15 KXS96995.1 - 0.00043 19.7 0.0 0.00084 18.7 0.0 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 KXS96995.1 - 0.00069 20.0 0.1 0.00069 20.0 0.1 2.7 3 0 0 3 3 3 1 AAA ATPase domain AAA PF00004.29 KXS96995.1 - 0.0011 19.4 0.1 0.0043 17.5 0.0 2.1 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXS96995.1 - 0.019 15.3 0.9 0.38 11.0 0.3 3.0 1 1 1 2 2 2 0 AAA domain DUF2075 PF09848.9 KXS96995.1 - 0.019 14.2 0.6 0.041 13.1 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.14 KXS96995.1 - 0.03 14.3 0.0 0.072 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KXS96995.1 - 0.04 13.6 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain UvrD-helicase PF00580.21 KXS96995.1 - 0.044 13.3 0.0 0.14 11.7 0.0 1.8 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Zeta_toxin PF06414.12 KXS96995.1 - 0.07 12.4 0.1 0.75 9.0 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin DEAD PF00270.29 KXS96995.1 - 0.14 11.9 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase PhoH PF02562.16 KXS96995.1 - 0.18 11.2 0.1 1 8.8 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein GDC-P PF02347.16 KXS96996.1 - 8.5e-180 598.2 0.0 2.5e-167 557.1 0.0 2.5 3 0 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 KXS96996.1 - 2.1e-05 23.9 0.3 0.0001 21.7 0.0 2.0 2 0 0 2 2 2 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KXS96996.1 - 0.029 13.5 0.0 0.45 9.6 0.0 2.2 2 0 0 2 2 2 0 Aminotransferase class I and II SPO11_like PF03533.14 KXS96996.1 - 0.33 11.1 1.7 0.6 10.2 0.5 2.0 2 0 0 2 2 2 0 SPO11 homologue Aim21 PF11489.8 KXS96997.1 - 2.5e-136 456.5 79.8 2.5e-136 456.5 79.8 2.6 2 1 0 2 2 2 1 Altered inheritance of mitochondria protein 21 Acyl_transf_3 PF01757.22 KXS96999.1 - 2.4e-08 33.5 0.4 2.7e-08 33.3 0.4 1.0 1 0 0 1 1 1 1 Acyltransferase family OpgC_C PF10129.9 KXS96999.1 - 0.014 14.3 0.0 0.022 13.7 0.0 1.3 1 0 0 1 1 1 0 OpgC protein DUF1624 PF07786.12 KXS96999.1 - 0.074 12.6 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1624) FAD_binding_4 PF01565.23 KXS97001.1 - 7.5e-21 74.3 0.3 1.3e-20 73.6 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Acyl_transf_3 PF01757.22 KXS97002.1 - 1.6e-18 66.9 21.1 2.1e-13 50.1 3.3 2.2 1 1 1 2 2 2 2 Acyltransferase family FAD_binding_4 PF01565.23 KXS97003.1 - 7.5e-21 74.3 0.3 1.3e-20 73.6 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_4 PF01565.23 KXS97004.1 - 7.5e-21 74.3 0.3 1.3e-20 73.6 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Acyl_transf_3 PF01757.22 KXS97006.1 - 2.5e-16 59.7 12.2 2.9e-09 36.5 0.2 2.2 2 0 0 2 2 2 2 Acyltransferase family OpgC_C PF10129.9 KXS97006.1 - 0.18 10.7 0.0 0.18 10.7 0.0 2.8 3 1 0 3 3 3 0 OpgC protein Acyl_transf_3 PF01757.22 KXS97008.1 - 3e-06 26.6 19.7 4.9e-05 22.6 11.1 2.3 1 1 0 2 2 2 2 Acyltransferase family NADH-u_ox-rdase PF10785.9 KXS97009.1 - 2.4e-29 101.8 0.2 4.1e-29 101.1 0.2 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 KXS97009.1 - 1.5e-28 98.6 0.1 2.1e-28 98.1 0.1 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Actin PF00022.19 KXS97011.1 - 6.4e-29 100.8 0.0 1.3e-17 63.6 0.0 2.2 2 0 0 2 2 2 2 Actin Actin_micro PF17003.5 KXS97011.1 - 1.3e-05 24.5 0.0 0.012 14.9 0.0 2.2 2 0 0 2 2 2 2 Putative actin-like family DUF2114 PF09887.9 KXS97011.1 - 0.028 12.9 0.8 0.04 12.4 0.8 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2114) FtsA PF14450.6 KXS97011.1 - 0.052 14.0 0.0 0.17 12.3 0.0 2.0 2 1 0 2 2 2 0 Cell division protein FtsA HAD_2 PF13419.6 KXS97012.1 - 2.7e-08 34.1 0.0 1e-07 32.2 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXS97012.1 - 7.4e-07 29.7 0.0 2.2e-06 28.1 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXS97012.1 - 0.0002 21.3 0.0 0.28 11.3 0.0 3.2 3 0 0 3 3 3 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 KXS97012.1 - 0.036 14.2 0.0 0.38 10.9 0.0 2.6 3 1 0 3 3 3 0 Haloacid dehalogenase-like hydrolase Oxidored-like PF09791.9 KXS97013.1 - 6.1e-25 86.6 2.7 1.1e-24 85.8 2.7 1.5 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal Wtap PF17098.5 KXS97013.1 - 4.9e-05 23.3 0.0 8.4e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 WTAP/Mum2p family DUF3328 PF11807.8 KXS97016.1 - 1.3e-25 90.5 0.0 1.4e-25 90.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) UBA_5 PF16577.5 KXS97017.1 - 0.0009 19.3 0.1 1.7 8.8 0.0 2.5 1 1 1 2 2 2 2 UBA domain NTF2 PF02136.20 KXS97018.1 - 6.6e-32 110.6 0.1 7.7e-32 110.4 0.1 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain NTF2 PF02136.20 KXS97019.1 - 1.8e-32 112.4 0.1 2e-32 112.3 0.1 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF3431 PF11913.8 KXS97020.1 - 0.00014 21.7 0.0 0.00026 20.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) GST_N_3 PF13417.6 KXS97020.1 - 0.00045 20.6 0.0 0.0012 19.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXS97020.1 - 0.036 14.4 0.0 0.11 12.8 0.0 1.9 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Cg6151-P PF10233.9 KXS97022.1 - 8.1e-45 151.8 16.0 9.7e-45 151.5 16.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P COPI_assoc PF08507.10 KXS97022.1 - 0.013 15.5 12.9 0.019 15.0 12.9 1.2 1 0 0 1 1 1 0 COPI associated protein DUF1741 PF08427.10 KXS97022.1 - 0.16 11.6 0.3 0.25 11.0 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1741) DUF3784 PF12650.7 KXS97022.1 - 0.92 9.8 13.5 0.99 9.6 5.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) DUF4149 PF13664.6 KXS97022.1 - 1.1 9.6 8.1 0.43 10.9 2.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) TraP PF07296.11 KXS97022.1 - 1.4 8.1 4.0 0.32 10.2 0.4 1.6 2 0 0 2 2 2 0 TraP protein S_4TM PF18159.1 KXS97022.1 - 2.3 7.4 7.9 2.9 7.1 1.9 2.0 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain DUF2721 PF11026.8 KXS97022.1 - 6.2 6.7 14.9 1.4 8.8 5.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) DUF4231 PF14015.6 KXS97022.1 - 7.4 7.1 6.4 24 5.5 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) F-box PF00646.33 KXS97029.1 - 2e-06 27.5 0.1 4.1e-06 26.5 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXS97029.1 - 4.5e-05 23.3 0.1 0.00019 21.2 0.1 2.1 1 0 0 1 1 1 1 F-box-like SurE PF01975.17 KXS97030.1 - 1e-30 107.0 0.0 1.7e-30 106.3 0.0 1.3 1 0 0 1 1 1 1 Survival protein SurE zf-MYND PF01753.18 KXS97031.1 - 2.3e-09 37.2 8.9 4e-09 36.4 8.9 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KXS97031.1 - 0.02 15.2 6.1 0.035 14.4 6.1 1.3 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding DcpS PF05652.12 KXS97033.1 - 0.12 13.2 0.0 0.15 12.9 0.0 1.2 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme (DcpS) N-terminal CRAL_TRIO PF00650.20 KXS97034.1 - 2.6e-35 121.5 0.0 6.8e-35 120.1 0.0 1.7 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KXS97034.1 - 4.1e-07 30.1 0.2 1e-06 28.8 0.2 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KXS97034.1 - 0.0081 16.3 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain F-box-like PF12937.7 KXS97037.1 - 1.7e-08 34.2 0.1 3.3e-08 33.3 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS97037.1 - 0.00016 21.5 0.0 0.00038 20.2 0.0 1.7 1 0 0 1 1 1 1 F-box domain TPR_2 PF07719.17 KXS97037.1 - 0.0051 16.8 0.7 0.18 12.0 1.2 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KXS97037.1 - 0.0089 15.8 0.3 0.26 11.2 0.6 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat MIT PF04212.18 KXS97037.1 - 0.031 14.3 0.9 0.082 13.0 0.2 2.0 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_11 PF13414.6 KXS97037.1 - 0.034 13.8 1.7 0.72 9.6 0.0 2.9 3 0 0 3 3 3 0 TPR repeat Vps51 PF08700.11 KXS97038.1 - 9.9e-31 105.7 0.0 2.8e-30 104.2 0.0 1.8 1 0 0 1 1 1 1 Vps51/Vps67 Dor1 PF04124.12 KXS97038.1 - 0.00043 19.1 0.1 0.0006 18.6 0.1 1.2 1 0 0 1 1 1 1 Dor1-like family Sec5 PF15469.6 KXS97038.1 - 0.00066 19.5 0.0 0.0015 18.4 0.0 1.6 1 1 0 1 1 1 1 Exocyst complex component Sec5 IL22 PF14565.6 KXS97038.1 - 0.001 19.3 0.1 0.0018 18.6 0.1 1.3 1 0 0 1 1 1 1 Interleukin 22 IL-10-related T-cell-derived-inducible factor COG5 PF10392.9 KXS97038.1 - 0.0058 16.8 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 Golgi transport complex subunit 5 SLBP_RNA_bind PF15247.6 KXS97038.1 - 0.094 12.8 0.0 0.094 12.8 0.0 2.4 3 0 0 3 3 3 0 Histone RNA hairpin-binding protein RNA-binding domain FUSC PF04632.12 KXS97038.1 - 0.16 10.4 1.3 0.25 9.8 1.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family CarboxypepD_reg PF13620.6 KXS97039.1 - 0.054 13.8 0.1 0.27 11.5 0.0 2.0 3 0 0 3 3 3 0 Carboxypeptidase regulatory-like domain Methyltransf_11 PF08241.12 KXS97040.1 - 9.8e-17 61.4 0.0 2.3e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS97040.1 - 6e-16 58.9 0.0 1.5e-15 57.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS97040.1 - 1.4e-13 51.0 0.0 1.9e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KXS97040.1 - 1.5e-11 44.1 0.0 2e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KXS97040.1 - 2.9e-11 43.5 0.0 4.6e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXS97040.1 - 9.9e-11 41.4 0.0 1.8e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KXS97040.1 - 4.8e-10 40.1 0.0 1.6e-09 38.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Sterol_MT_C PF08498.10 KXS97040.1 - 6.8e-09 35.9 0.1 1.2e-08 35.1 0.1 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_32 PF13679.6 KXS97040.1 - 0.045 13.7 0.0 0.061 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.10 KXS97040.1 - 0.061 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_8 PF05148.15 KXS97040.1 - 0.084 12.7 0.0 0.2 11.5 0.0 1.6 1 1 0 1 1 1 0 Hypothetical methyltransferase DOT1 PF08123.13 KXS97040.1 - 0.12 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Proteasome PF00227.26 KXS97043.1 - 1.1e-45 155.5 0.1 1.4e-45 155.1 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 KXS97043.1 - 2e-13 49.5 2.5 2e-13 49.5 2.5 1.8 2 0 0 2 2 2 1 Proteasome beta subunits C terminal Pro-kuma_activ PF09286.11 KXS97044.1 - 3.1e-44 150.7 0.0 3.1e-43 147.5 0.0 2.1 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KXS97044.1 - 0.00089 18.6 0.0 0.0036 16.6 0.0 1.9 1 1 0 1 1 1 1 Subtilase family HATPase_c PF02518.26 KXS97045.1 - 2.8e-22 79.3 0.0 7.7e-22 77.9 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXS97045.1 - 7.6e-21 74.4 0.4 2e-20 73.0 0.4 1.8 1 0 0 1 1 1 1 Response regulator receiver domain PAS_4 PF08448.10 KXS97045.1 - 1.7e-12 47.6 0.0 1.9e-06 28.1 0.0 3.4 3 0 0 3 3 3 2 PAS fold HisKA PF00512.25 KXS97045.1 - 3.6e-09 36.5 0.1 9e-09 35.2 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 KXS97045.1 - 1.5e-05 25.2 0.0 0.003 17.8 0.0 3.3 3 0 0 3 3 3 1 PAS domain PAS_8 PF13188.7 KXS97045.1 - 0.022 14.8 0.0 0.064 13.3 0.0 1.8 1 0 0 1 1 1 0 PAS domain ER-remodelling PF14755.6 KXS97045.1 - 0.046 14.0 5.4 0.097 13.0 5.4 1.5 1 0 0 1 1 1 0 Intracellular membrane remodeller HATPase_c_3 PF13589.6 KXS97045.1 - 0.12 12.2 0.0 0.48 10.3 0.0 2.0 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Mito_carr PF00153.27 KXS97047.1 - 5.8e-58 192.8 1.3 1.4e-18 66.5 0.0 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KXS97047.1 - 0.007 15.6 0.1 0.057 12.6 0.0 2.2 3 0 0 3 3 3 1 Gammaproteobacterial serine protease RNase_H PF00075.24 KXS97048.1 - 1.9e-22 80.0 0.1 2.1e-22 79.8 0.1 1.1 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 KXS97048.1 - 9e-06 25.5 0.0 0.11 12.3 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase-like Cyclin_C PF02984.19 KXS97048.1 - 0.071 13.2 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Cyclin, C-terminal domain COesterase PF00135.28 KXS97049.1 - 3.1e-89 300.2 0.0 4.4e-89 299.7 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Peroxidase_2 PF01328.17 KXS97049.1 - 6.1e-50 170.4 0.0 1e-49 169.6 0.0 1.3 1 0 0 1 1 1 1 Peroxidase, family 2 Abhydrolase_3 PF07859.13 KXS97049.1 - 0.032 14.1 0.7 0.28 11.0 0.7 2.2 1 1 0 1 1 1 0 alpha/beta hydrolase fold NUP214 PF16755.5 KXS97050.1 - 0.0013 18.1 0.0 0.88 8.7 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 Golgin_A5 PF09787.9 KXS97050.1 - 0.0017 17.9 2.1 0.0033 17.0 2.1 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 5 SDA1 PF05285.12 KXS97050.1 - 0.0022 17.5 17.7 0.0036 16.8 17.7 1.2 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 KXS97050.1 - 0.011 14.1 20.1 0.018 13.3 20.1 1.2 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.12 KXS97050.1 - 2.5 6.6 21.4 5.8 5.4 21.4 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DNA_pol_phi PF04931.13 KXS97050.1 - 7.3 4.6 32.5 11 4.0 32.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi YL1 PF05764.13 KXS97050.1 - 8.5 6.4 27.9 0.14 12.2 20.4 1.8 2 0 0 2 2 2 0 YL1 nuclear protein CDC45 PF02724.14 KXS97050.1 - 8.8 4.5 16.2 15 3.7 16.2 1.2 1 0 0 1 1 1 0 CDC45-like protein adh_short PF00106.25 KXS97061.1 - 8e-52 175.5 0.2 1.1e-51 175.1 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS97061.1 - 1.3e-31 109.9 0.1 1.7e-31 109.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS97061.1 - 1.4e-12 47.9 0.1 1.9e-12 47.4 0.1 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXS97061.1 - 0.011 14.9 0.2 0.022 13.9 0.2 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KXS97061.1 - 0.034 14.4 0.1 0.059 13.6 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DIOX_N PF14226.6 KXS97062.1 - 8.4e-26 91.0 0.0 1.4e-25 90.3 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXS97062.1 - 1.9e-17 63.6 0.0 5.9e-17 62.0 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Arb1 PF09692.10 KXS97063.1 - 3.9e-111 372.1 0.1 5e-111 371.7 0.1 1.1 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 La PF05383.17 KXS97063.1 - 7e-14 51.6 0.0 1.3e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 La domain TPR_14 PF13428.6 KXS97064.1 - 9.5e-12 44.7 26.7 0.27 12.1 0.0 11.9 13 2 2 15 15 11 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXS97064.1 - 8e-11 41.3 4.3 0.012 15.8 0.0 5.7 6 0 0 6 6 5 3 Tetratricopeptide repeat Suf PF05843.14 KXS97064.1 - 7.6e-09 36.0 11.2 0.058 13.4 0.1 6.0 3 1 1 5 5 5 3 Suppressor of forked protein (Suf) TPR_2 PF07719.17 KXS97064.1 - 2.7e-07 30.2 11.6 0.0073 16.3 0.0 7.2 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXS97064.1 - 3.2e-07 30.7 2.9 0.06 13.9 0.0 5.9 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXS97064.1 - 4.2e-07 30.2 5.1 2.3 8.6 0.0 6.8 6 1 0 6 6 6 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 KXS97064.1 - 2.5e-05 24.3 12.6 0.44 10.5 0.2 6.6 7 1 0 7 7 7 1 Mad3/BUB1 homology region 1 TPR_6 PF13174.6 KXS97064.1 - 0.0042 17.6 7.1 3.1 8.6 0.0 6.4 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_4 PF07721.14 KXS97064.1 - 0.0067 16.9 0.3 1 10.2 0.0 3.6 2 0 0 2 2 2 1 Tetratricopeptide repeat MIT PF04212.18 KXS97064.1 - 0.013 15.6 0.6 1 9.5 0.1 3.9 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_16 PF13432.6 KXS97064.1 - 0.026 15.2 9.7 4.4 8.0 0.0 6.2 8 0 0 8 8 5 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 KXS97064.1 - 0.03 13.8 0.0 0.12 11.9 0.0 2.1 1 0 0 1 1 1 0 SHNi-TPR TPR_7 PF13176.6 KXS97064.1 - 0.031 14.3 9.3 0.035 14.1 0.0 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXS97064.1 - 0.037 13.9 13.1 0.24 11.3 0.1 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXS97064.1 - 0.08 12.8 0.9 1.4 8.9 0.0 3.6 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 KXS97064.1 - 0.13 12.7 8.3 2.1 8.9 0.0 5.6 8 0 0 8 8 6 0 Tetratricopeptide repeat CAP_N PF01213.19 KXS97064.1 - 0.17 11.3 2.1 0.39 10.2 2.1 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal NRDE-2 PF08424.10 KXS97064.1 - 0.27 10.3 16.8 0.057 12.5 1.1 5.9 3 2 2 6 6 6 0 NRDE-2, necessary for RNA interference ALG3 PF05208.13 KXS97065.1 - 5.4e-136 453.7 15.5 6.5e-136 453.4 15.5 1.1 1 0 0 1 1 1 1 ALG3 protein PPR_2 PF13041.6 KXS97066.1 - 0.061 13.5 0.0 2.3 8.5 0.0 2.6 2 0 0 2 2 2 0 PPR repeat family PPR_1 PF12854.7 KXS97066.1 - 0.18 11.5 0.1 0.42 10.4 0.1 1.5 1 0 0 1 1 1 0 PPR repeat Synaptobrevin PF00957.21 KXS97067.1 - 1.8e-31 107.8 0.0 2.7e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KXS97067.1 - 1e-28 99.2 0.0 1.7e-28 98.4 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF2628 PF10947.8 KXS97067.1 - 0.18 12.1 1.5 0.38 11.1 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) Transp_cyt_pur PF02133.15 KXS97068.1 - 1.1e-82 278.2 34.5 5e-51 173.8 8.5 2.0 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin DUF3606 PF12244.8 KXS97068.1 - 0.2 11.6 0.3 0.43 10.5 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3606) Aldedh PF00171.22 KXS97069.1 - 3.8e-145 484.0 0.1 4.9e-145 483.6 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KXS97069.1 - 0.013 14.6 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) p450 PF00067.22 KXS97072.1 - 2.9e-34 118.6 0.0 3.9e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DFF-C PF09033.10 KXS97072.1 - 0.028 14.3 0.2 0.088 12.7 0.3 1.7 2 0 0 2 2 2 0 DNA Fragmentation factor 45kDa, C terminal domain ATP-synt_D PF01813.17 KXS97073.1 - 7.6e-71 238.0 4.7 9.7e-71 237.7 4.7 1.1 1 0 0 1 1 1 1 ATP synthase subunit D DUF1664 PF07889.12 KXS97073.1 - 0.19 11.8 3.3 0.28 11.2 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Ribosomal_L6e PF01159.19 KXS97073.1 - 0.5 10.9 6.2 1.6 9.3 6.2 1.8 1 0 0 1 1 1 0 Ribosomal protein L6e Sec62 PF03839.16 KXS97073.1 - 2.5 7.6 5.5 4.4 6.7 5.5 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 ABC2_membrane PF01061.24 KXS97074.1 - 0.016 14.7 2.8 0.019 14.4 2.8 1.1 1 0 0 1 1 1 0 ABC-2 type transporter ABC2_membrane PF01061.24 KXS97075.1 - 0.016 14.7 2.8 0.019 14.4 2.8 1.1 1 0 0 1 1 1 0 ABC-2 type transporter Mlh1_C PF16413.5 KXS97076.1 - 1.7e-94 316.2 0.0 3e-94 315.4 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 KXS97076.1 - 1.6e-31 108.4 0.0 2.7e-31 107.7 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KXS97076.1 - 1.5e-11 44.3 0.0 3.3e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KXS97076.1 - 2.9e-07 31.0 0.0 6.9e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RNA_pol_Rpb8 PF03870.15 KXS97077.1 - 1e-41 142.4 0.0 1.2e-41 142.2 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 KXS97077.1 - 0.043 13.9 0.1 6 7.0 0.0 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase, subunit G IPK PF03770.16 KXS97078.1 - 3.9e-52 177.0 0.0 4.9e-52 176.7 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase Glyco_hydro_3_C PF01915.22 KXS97079.1 - 3.9e-43 147.8 0.0 1.7e-42 145.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXS97079.1 - 4e-31 108.6 0.0 7e-31 107.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXS97079.1 - 1.1e-16 60.6 0.1 2e-16 59.8 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3_C PF01915.22 KXS97080.1 - 3.6e-43 147.9 0.0 1.6e-42 145.8 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXS97080.1 - 3.8e-31 108.6 0.0 6.6e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXS97080.1 - 1.1e-16 60.7 0.1 1.9e-16 59.9 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain PAXNEB PF05625.11 KXS97081.1 - 4.8e-100 335.3 0.0 6.6e-100 334.8 0.0 1.1 1 0 0 1 1 1 1 PAXNEB protein Mitoc_L55 PF09776.9 KXS97081.1 - 0.17 11.6 0.5 0.79 9.5 0.0 2.1 1 1 1 2 2 2 0 Mitochondrial ribosomal protein L55 Ion_trans PF00520.31 KXS97082.1 - 2.6e-08 33.4 29.3 4.4e-08 32.7 29.3 1.4 1 0 0 1 1 1 1 Ion transport protein Peroxidase_2 PF01328.17 KXS97084.1 - 3.3e-48 164.7 0.0 5.5e-48 164.0 0.0 1.3 1 0 0 1 1 1 1 Peroxidase, family 2 zf-U11-48K PF05253.12 KXS97084.1 - 0.035 14.0 1.0 0.11 12.4 1.0 1.9 1 0 0 1 1 1 0 U11-48K-like CHHC zinc finger TolA_bind_tri PF16331.5 KXS97085.1 - 0.02 15.0 0.1 0.03 14.4 0.1 1.3 1 0 0 1 1 1 0 TolA binding protein trimerisation Shugoshin_N PF07558.11 KXS97085.1 - 0.041 13.8 0.0 0.069 13.0 0.0 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region DUF4349 PF14257.6 KXS97085.1 - 0.046 13.2 0.1 0.053 12.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DUF1192 PF06698.11 KXS97085.1 - 0.048 13.7 0.0 0.084 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DUF4743 PF15916.5 KXS97086.1 - 3.4e-13 49.6 0.0 5.5e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 KXS97086.1 - 1.7e-11 44.3 0.0 3.2e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain eIF-1a PF01176.19 KXS97088.1 - 8.7e-17 60.7 0.0 1.2e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 DUF775 PF05603.12 KXS97089.1 - 6.9e-66 221.6 0.0 7.7e-66 221.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) SLAC1 PF03595.17 KXS97090.1 - 1.1e-80 271.4 48.7 1.2e-80 271.2 48.7 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Orf78 PF06024.12 KXS97090.1 - 0.91 9.9 2.3 9.4 6.6 0.1 2.6 2 0 0 2 2 2 0 Orf78 (ac78) Sigma70_r4_2 PF08281.12 KXS97114.1 - 0.0034 17.0 1.0 0.02 14.5 0.0 2.4 3 0 0 3 3 3 1 Sigma-70, region 4 HTH_AsnC-type PF13404.6 KXS97114.1 - 0.019 14.8 0.2 0.05 13.4 0.1 1.8 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain PROCN PF08083.11 KXS97115.1 - 5.4e-235 779.6 7.8 5.4e-235 779.6 7.8 2.0 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 KXS97115.1 - 1.1e-127 424.4 1.5 2e-127 423.5 1.5 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 KXS97115.1 - 3.4e-89 296.8 2.1 1.1e-88 295.2 2.1 2.0 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 KXS97115.1 - 1.4e-80 268.6 2.8 1.4e-80 268.6 2.8 1.9 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 KXS97115.1 - 9e-71 236.2 0.1 1.8e-70 235.2 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 KXS97115.1 - 1.9e-46 156.3 0.5 5e-46 155.0 0.5 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 KXS97115.1 - 2.2e-43 147.1 0.2 6.4e-43 145.6 0.0 2.0 2 0 0 2 2 2 1 PROCT (NUC072) domain Sugar_tr PF00083.24 KXS97116.1 - 8.9e-107 357.7 20.8 1.1e-106 357.5 20.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS97116.1 - 1.1e-30 106.8 29.9 5.3e-29 101.3 20.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_5 PF05631.14 KXS97116.1 - 1.3e-07 30.9 0.9 1.3e-07 30.9 0.9 2.4 2 1 0 2 2 2 1 Sugar-tranasporters, 12 TM fn3 PF00041.21 KXS97117.1 - 2.8e-12 46.8 1.9 0.00015 22.0 0.1 3.7 3 1 0 3 3 3 3 Fibronectin type III domain Lipase_GDSL_2 PF13472.6 KXS97117.1 - 2.5e-10 41.0 1.5 3.5e-09 37.3 0.3 2.6 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.6 KXS97117.1 - 0.016 15.3 0.0 0.14 12.3 0.0 2.1 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXS97117.1 - 0.016 15.2 0.0 0.031 14.3 0.0 1.5 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase ENTH PF01417.20 KXS97120.1 - 2.3e-47 160.1 0.4 3.4e-47 159.6 0.4 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 KXS97120.1 - 0.00032 19.8 0.0 0.00047 19.2 0.0 1.2 1 0 0 1 1 1 1 ANTH domain DUF5102 PF17104.5 KXS97120.1 - 0.035 14.2 9.2 1.2 9.1 0.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5102) VHS PF00790.19 KXS97120.1 - 0.1 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 VHS domain Ribosomal_L14 PF00238.19 KXS97121.1 - 8.6e-34 116.2 0.0 1.2e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Pro_isomerase PF00160.21 KXS97122.1 - 7.8e-41 140.0 0.2 1e-40 139.6 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Bac_rhamnosid6H PF17389.2 KXS97123.1 - 2e-85 287.1 0.1 2.5e-85 286.7 0.1 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 KXS97123.1 - 5.2e-52 176.1 0.0 9e-52 175.4 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 KXS97123.1 - 1.3e-16 60.4 0.0 2.6e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 KXS97123.1 - 1.8e-13 50.1 0.0 3.9e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain DUF608 PF04685.13 KXS97123.1 - 6.2e-05 22.3 0.0 9.8e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl-hydrolase family 116, catalytic region Sugar_tr PF00083.24 KXS97124.1 - 4.4e-07 29.1 0.4 5.1e-07 28.9 0.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Kinocilin PF15033.6 KXS97124.1 - 0.041 13.5 0.1 0.05 13.2 0.1 1.1 1 0 0 1 1 1 0 Kinocilin protein DUF498 PF04430.14 KXS97126.1 - 4.4e-30 103.9 0.0 7.1e-30 103.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Myb_DNA-binding PF00249.31 KXS97127.1 - 1.2e-12 47.8 0.5 2.4e-06 27.6 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXS97127.1 - 8.5e-08 32.3 0.1 0.0056 16.9 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXS97128.1 - 5.6e-10 39.3 0.3 2e-06 27.9 0.0 2.9 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KXS97128.1 - 1.5e-08 34.7 0.1 0.0015 18.7 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain DUF247 PF03140.15 KXS97128.1 - 0.031 13.5 0.0 0.067 12.4 0.0 1.5 1 0 0 1 1 1 0 Plant protein of unknown function TFIIA PF03153.13 KXS97128.1 - 0.14 12.1 36.7 0.19 11.7 36.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Myb_DNA-bind_6 PF13921.6 KXS97129.1 - 6.5e-10 39.1 0.3 2.2e-06 27.8 0.0 2.9 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KXS97129.1 - 1.7e-08 34.5 0.1 0.0016 18.6 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain DUF247 PF03140.15 KXS97129.1 - 0.034 13.4 0.0 0.073 12.3 0.0 1.5 1 0 0 1 1 1 0 Plant protein of unknown function TFIIA PF03153.13 KXS97129.1 - 0.14 12.1 36.6 0.2 11.7 36.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Chorion_3 PF05387.11 KXS97130.1 - 0.74 9.4 3.9 0.93 9.1 3.9 1.2 1 0 0 1 1 1 0 Chorion family 3 Ribosomal_L34e PF01199.18 KXS97131.1 - 1.7e-42 143.6 3.8 2.7e-42 143.0 3.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L34e DUF5437 PF17505.2 KXS97131.1 - 0.12 12.4 1.2 0.3 11.1 0.2 2.2 2 1 0 2 2 2 0 Family of unknown function (DUF5437) UDPGP PF01704.18 KXS97132.1 - 2.6e-190 632.4 0.0 3.2e-190 632.1 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase FRG1 PF06229.12 KXS97134.1 - 2.8e-40 138.1 11.0 2.8e-40 138.1 11.0 2.3 2 1 0 2 2 2 1 FRG1-like domain Fascin PF06268.13 KXS97134.1 - 1.2e-05 25.5 0.1 0.0086 16.3 0.0 2.3 1 1 1 2 2 2 2 Fascin domain Phage_spike_2 PF18781.1 KXS97134.1 - 0.061 13.4 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Phage spike trimer ArabFuran-catal PF09206.11 KXS97135.1 - 1.1e-150 501.3 9.7 1.1e-150 501.3 9.7 1.5 2 0 0 2 2 2 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.13 KXS97135.1 - 7.3e-47 158.9 0.1 1.2e-46 158.2 0.1 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) domain Abhydrolase_3 PF07859.13 KXS97148.1 - 9.2e-17 61.6 0.0 2.1e-16 60.4 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXS97148.1 - 1.8e-05 24.4 0.0 0.017 14.6 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 KXS97148.1 - 0.00021 20.3 0.0 0.00031 19.8 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme COesterase PF00135.28 KXS97148.1 - 0.0004 19.4 0.0 0.00069 18.6 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Chlorophyllase PF07224.11 KXS97148.1 - 0.0008 18.5 0.0 0.0012 18.0 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase AXE1 PF05448.12 KXS97148.1 - 0.041 12.5 0.0 1.7 7.2 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Say1_Mug180 PF10340.9 KXS97148.1 - 0.1 11.5 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase Peptidase_S15 PF02129.18 KXS97148.1 - 0.17 11.5 0.0 0.92 9.0 0.0 1.9 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Mannosyl_trans3 PF11051.8 KXS97150.1 - 0.022 14.1 0.0 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative Glyco_transf_8 PF01501.20 KXS97150.1 - 0.23 11.0 2.2 0.24 10.9 0.1 2.1 2 1 0 2 2 2 0 Glycosyl transferase family 8 IBR PF01485.21 KXS97151.1 - 1.5e-10 41.2 18.7 2e-06 27.9 4.2 4.0 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 KXS97151.1 - 2.4e-05 24.2 2.6 2.4e-05 24.2 2.6 3.9 4 2 0 4 4 4 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KXS97151.1 - 3.4e-05 23.6 5.9 3.4e-05 23.6 5.9 4.4 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXS97151.1 - 3.9e-05 23.5 8.2 3.9e-05 23.5 8.2 4.5 3 2 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KXS97151.1 - 0.00016 21.4 5.3 0.00016 21.4 5.3 4.1 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXS97151.1 - 0.0039 17.5 10.5 0.0039 17.5 10.5 4.5 4 0 0 4 4 4 1 Ring finger domain Abhydrolase_1 PF00561.20 KXS97152.1 - 1.4e-09 38.0 0.0 4.5e-05 23.2 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXS97152.1 - 6.7e-09 35.4 0.0 2e-08 33.8 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXS97152.1 - 3.9e-06 27.6 0.1 4.9e-06 27.3 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KXS97152.1 - 0.0018 18.1 0.0 1.8 8.3 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.18 KXS97152.1 - 0.012 15.2 0.0 0.02 14.5 0.0 1.3 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) IBR PF01485.21 KXS97153.1 - 1e-10 41.6 39.0 1.7e-06 28.2 5.6 4.4 4 0 0 4 4 4 3 IBR domain, a half RING-finger domain Rad50_zn_hook PF04423.14 KXS97153.1 - 0.92 9.4 6.2 20 5.1 0.1 3.9 4 0 0 4 4 4 0 Rad50 zinc hook motif TRAUB PF08164.12 KXS97154.1 - 1.4e-29 102.4 3.3 1.4e-29 102.4 0.2 2.7 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 KXS97154.1 - 1.2e-25 90.9 2.2 1.2e-25 90.9 2.2 2.6 3 0 0 3 3 3 1 Apoptosis antagonizing transcription factor SYCE1 PF15233.6 KXS97154.1 - 1 9.4 9.0 1.4 9.0 3.9 2.6 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 AMP-binding PF00501.28 KXS97155.1 - 5.8e-276 914.7 0.0 4.2e-74 249.6 0.0 4.2 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.20 KXS97155.1 - 3.8e-162 540.1 0.0 5.7e-37 127.5 0.0 5.9 5 1 0 5 5 5 5 Condensation domain PP-binding PF00550.25 KXS97155.1 - 3.1e-45 152.4 7.3 3.6e-11 43.3 0.0 5.4 5 0 0 5 5 5 4 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KXS97155.1 - 4.3e-08 34.0 0.0 0.32 12.0 0.0 4.1 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain GH3 PF03321.13 KXS97155.1 - 0.16 10.8 0.4 1.3 7.8 0.0 2.7 4 0 0 4 4 4 0 GH3 auxin-responsive promoter RCC1 PF00415.18 KXS97156.1 - 4.7e-12 46.3 5.6 5.5e-05 23.7 0.0 6.0 5 1 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KXS97156.1 - 1.5e-07 31.0 4.1 1.1 9.1 0.2 4.8 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat TFIIE-A_C PF11521.8 KXS97157.1 - 0.34 11.2 4.1 0.9 9.9 4.1 1.7 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha Ribosomal_60s PF00428.19 KXS97157.1 - 6.7 7.4 11.0 9.8 6.8 11.1 1.4 1 1 0 1 1 1 0 60s Acidic ribosomal protein vATP-synt_E PF01991.18 KXS97158.1 - 3.2e-59 199.7 14.1 4.2e-59 199.3 14.1 1.2 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Gmad2 PF10648.9 KXS97158.1 - 0.024 14.9 0.0 0.082 13.2 0.0 1.9 1 0 0 1 1 1 0 Immunoglobulin-like domain of bacterial spore germination HTH_38 PF13936.6 KXS97159.1 - 3.7e-08 33.0 2.2 0.0091 15.7 0.0 3.4 3 0 0 3 3 3 2 Helix-turn-helix domain GcrA PF07750.11 KXS97159.1 - 4.5e-07 30.4 5.6 0.0014 19.0 0.0 3.8 3 1 1 4 4 4 2 GcrA cell cycle regulator Myb_DNA-binding PF00249.31 KXS97159.1 - 5.7e-06 26.4 0.1 0.00081 19.5 0.0 3.0 3 0 0 3 3 3 1 Myb-like DNA-binding domain HTH_23 PF13384.6 KXS97159.1 - 0.00047 19.9 1.8 0.19 11.5 0.0 3.3 3 0 0 3 3 3 2 Homeodomain-like domain Sigma70_r4_2 PF08281.12 KXS97159.1 - 0.0012 18.4 1.0 2.1 8.1 0.0 2.9 3 0 0 3 3 3 2 Sigma-70, region 4 GerE PF00196.19 KXS97159.1 - 0.0051 16.3 0.0 0.88 9.2 0.0 2.5 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family HTH_32 PF13565.6 KXS97159.1 - 0.017 15.7 5.7 1.2 9.8 0.4 3.2 3 1 0 3 3 3 0 Homeodomain-like domain HTH_7 PF02796.15 KXS97159.1 - 0.065 13.3 0.5 1.6 8.9 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase Sigma70_r4 PF04545.16 KXS97159.1 - 0.077 12.5 0.3 14 5.3 0.0 3.2 3 0 0 3 3 3 0 Sigma-70, region 4 Myb_DNA-bind_6 PF13921.6 KXS97159.1 - 0.14 12.4 0.1 11 6.4 0.0 2.7 2 0 0 2 2 2 0 Myb-like DNA-binding domain Glyco_hydro_64 PF16483.5 KXS97160.1 - 2e-120 402.5 0.4 2.3e-120 402.3 0.4 1.0 1 0 0 1 1 1 1 Beta-1,3-glucanase PRA1 PF03208.19 KXS97161.1 - 0.039 13.6 0.4 0.039 13.6 0.4 2.2 3 0 0 3 3 3 0 PRA1 family protein YrhC PF14143.6 KXS97161.1 - 0.11 12.7 1.3 0.23 11.6 1.3 1.5 1 0 0 1 1 1 0 YrhC-like protein Ribosomal_S14 PF00253.21 KXS97162.1 - 1.9e-11 43.6 1.0 3.5e-11 42.7 1.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Mg_trans_NIPA PF05653.14 KXS97163.1 - 1.2e-17 64.0 8.6 2.1e-17 63.2 8.6 1.4 1 1 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KXS97163.1 - 0.00025 21.2 0.4 0.00025 21.2 0.4 3.2 2 1 1 3 3 3 1 EamA-like transporter family MAP17 PF15807.5 KXS97163.1 - 0.068 13.4 0.0 0.29 11.4 0.0 2.1 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Peptidase_S8 PF00082.22 KXS97164.1 - 1e-34 120.2 10.5 2.4e-34 119.0 10.4 1.5 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KXS97164.1 - 0.032 14.9 0.0 0.057 14.1 0.0 1.3 1 0 0 1 1 1 0 Peptidase inhibitor I9 RIBIOP_C PF04950.12 KXS97165.1 - 9.5e-108 360.0 0.0 2e-107 359.0 0.0 1.6 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KXS97165.1 - 2.9e-14 52.9 0.2 1.8e-13 50.4 0.2 2.2 1 1 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.27 KXS97165.1 - 0.03 13.8 0.0 0.055 13.0 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain DSHCT PF08148.12 KXS97173.1 - 2.3e-52 177.0 0.1 7.4e-52 175.3 0.1 1.9 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 KXS97173.1 - 8.7e-40 135.7 0.1 1.8e-39 134.7 0.1 1.5 1 0 0 1 1 1 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 KXS97173.1 - 2.3e-30 106.4 1.3 5.6e-30 105.2 1.3 1.7 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 KXS97173.1 - 3.8e-17 62.6 0.0 8.5e-17 61.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase IBN_N PF03810.19 KXS97173.1 - 2.4e-10 40.2 5.3 9.9e-09 35.0 0.0 5.0 6 0 0 6 6 6 1 Importin-beta N-terminal domain Helicase_C PF00271.31 KXS97173.1 - 5.7e-06 26.6 0.0 1.7e-05 25.1 0.0 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain Cse1 PF08506.10 KXS97173.1 - 0.0001 21.2 0.1 0.00036 19.5 0.0 1.8 2 0 0 2 2 2 1 Cse1 Sigma70_ner PF04546.13 KXS97173.1 - 0.0051 16.7 2.9 0.0051 16.7 2.9 2.5 2 0 0 2 2 2 1 Sigma-70, non-essential region RTP1_C1 PF10363.9 KXS97173.1 - 0.055 13.7 0.4 0.37 11.0 0.1 2.6 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Xpo1 PF08389.12 KXS97173.1 - 0.073 13.1 0.3 0.69 10.0 0.0 2.9 2 0 0 2 2 2 0 Exportin 1-like protein RIX1 PF08167.12 KXS97173.1 - 0.26 11.0 4.4 15 5.3 0.0 4.9 6 0 0 6 6 6 0 rRNA processing/ribosome biogenesis Adaptin_N PF01602.20 KXS97175.1 - 1.5e-125 419.8 4.6 1.8e-125 419.5 4.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 KXS97175.1 - 2.3e-40 137.3 0.0 5.9e-40 136.0 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 KXS97175.1 - 9.8e-19 67.7 0.0 1.8e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 KXS97175.1 - 0.0004 20.5 1.7 0.11 12.5 0.0 3.1 1 1 2 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KXS97175.1 - 0.0035 17.7 0.3 4.8 7.6 0.0 4.3 3 1 0 3 3 3 1 HEAT repeats GFO_IDH_MocA PF01408.22 KXS97176.1 - 5.9e-16 59.4 0.0 9.8e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KXS97176.1 - 0.17 12.5 0.0 0.33 11.6 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain RdRP PF05183.12 KXS97177.1 - 1.1e-176 589.0 0.0 1.4e-176 588.6 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase Sulfatase PF00884.23 KXS97178.1 - 1.5e-61 208.5 2.8 1.8e-61 208.3 1.9 1.5 2 0 0 2 2 2 1 Sulfatase Phosphodiest PF01663.22 KXS97178.1 - 7.9e-06 25.7 0.1 4e-05 23.4 0.2 1.9 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KXS97178.1 - 0.0098 14.5 0.0 0.021 13.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF4976 PF16347.5 KXS97178.1 - 0.014 15.6 0.1 0.033 14.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) DIOX_N PF14226.6 KXS97179.1 - 3.1e-16 60.2 0.0 5.9e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXS97179.1 - 4.5e-11 43.1 0.0 7.5e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ureidogly_lyase PF04115.12 KXS97180.1 - 4.4e-58 196.1 0.0 5.4e-58 195.9 0.0 1.1 1 0 0 1 1 1 1 Ureidoglycolate lyase DUF1275 PF06912.11 KXS97181.1 - 1.8e-45 155.2 14.4 2.3e-45 154.9 14.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) F-box-like_2 PF13013.6 KXS97183.1 - 0.012 15.6 0.1 0.028 14.4 0.1 1.6 1 0 0 1 1 1 0 F-box-like domain DUF1673 PF07895.11 KXS97184.1 - 0.17 11.6 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) Rick_17kDa_Anti PF05433.15 KXS97184.1 - 1.5 8.7 7.9 0.16 11.9 2.7 2.0 2 0 0 2 2 2 0 Glycine zipper 2TM domain RINT1_TIP1 PF04437.13 KXS97185.1 - 4.8e-185 616.2 0.0 8.6e-185 615.4 0.0 1.4 1 0 0 1 1 1 1 RINT-1 / TIP-1 family Bul1_C PF04426.12 KXS97185.1 - 0.11 11.9 1.1 0.21 10.9 1.1 1.4 1 0 0 1 1 1 0 Bul1 C terminus WASH-7_mid PF14744.6 KXS97185.1 - 0.34 9.9 3.8 0.72 8.9 3.8 1.4 1 0 0 1 1 1 0 WASH complex subunit 7 Snapin_Pallidin PF14712.6 KXS97185.1 - 0.55 10.7 10.4 5.2 7.6 3.7 3.7 4 0 0 4 4 4 0 Snapin/Pallidin CRISPR_Cse2 PF09485.10 KXS97185.1 - 2.1 8.9 12.5 0.6 10.6 7.3 2.7 2 1 1 3 3 3 0 CRISPR-associated protein Cse2 (CRISPR_cse2) Acetyltransf_13 PF13880.6 KXS97186.1 - 5.1e-23 80.8 0.1 2.7e-22 78.5 0.1 2.2 1 1 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 KXS97186.1 - 5e-14 51.8 3.3 1.1e-13 50.7 3.1 1.7 2 0 0 2 2 2 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_7 PF13508.7 KXS97186.1 - 0.0013 19.2 0.0 0.0025 18.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXS97186.1 - 0.0015 18.8 0.1 0.0033 17.7 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 KXS97186.1 - 0.0036 17.4 0.1 0.019 15.1 0.0 2.1 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.7 KXS97186.1 - 0.059 13.3 0.0 0.25 11.3 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXS97186.1 - 0.064 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FlaF PF07309.11 KXS97186.1 - 0.08 13.0 1.0 0.17 11.9 1.0 1.5 1 0 0 1 1 1 0 Flagellar protein FlaF LsmAD PF06741.13 KXS97186.1 - 0.32 11.6 1.7 0.93 10.1 1.7 1.7 1 0 0 1 1 1 0 LsmAD domain Gln-synt_C PF00120.24 KXS97187.1 - 1.1e-61 208.7 0.0 1.8e-61 208.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.14 KXS97187.1 - 3.7e-12 46.6 0.0 7e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase Gln-synt_N_2 PF16952.5 KXS97187.1 - 6.8e-05 22.7 0.0 0.00046 20.0 0.0 2.1 2 0 0 2 2 2 1 Glutamine synthetase N-terminal domain CFEM PF05730.11 KXS97188.1 - 1.1e-07 31.8 12.5 1.9e-07 31.1 12.5 1.4 1 0 0 1 1 1 1 CFEM domain Cupin_1 PF00190.22 KXS97189.1 - 6.4e-40 136.2 0.0 9.9e-20 70.7 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 KXS97189.1 - 3.4e-25 87.6 0.7 6e-13 48.3 0.1 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KXS97189.1 - 4.2e-10 39.2 0.0 0.00023 20.8 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 KXS97189.1 - 2.1e-06 27.7 0.2 0.0046 16.9 0.1 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain CENP-C_C PF11699.8 KXS97189.1 - 0.0095 16.1 0.0 1.5 9.1 0.0 2.5 2 0 0 2 2 2 1 Mif2/CENP-C like MannoseP_isomer PF01050.18 KXS97189.1 - 0.015 15.2 0.0 0.34 10.8 0.0 2.1 2 0 0 2 2 2 0 Mannose-6-phosphate isomerase ARD PF03079.14 KXS97189.1 - 0.043 14.0 0.1 3.6 7.8 0.0 2.3 2 0 0 2 2 2 0 ARD/ARD' family DUF2013 PF09431.10 KXS97190.1 - 7.9e-50 168.6 0.0 2.1e-49 167.2 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) Pox_Rap94 PF03294.14 KXS97190.1 - 0.12 10.4 0.5 0.18 9.8 0.5 1.1 1 0 0 1 1 1 0 RNA polymerase-associated transcription specificity factor, Rap94 DUF4240 PF14024.6 KXS97190.1 - 0.72 10.0 3.2 47 4.2 0.1 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF4240) Y_phosphatase PF00102.27 KXS97191.1 - 1.9e-51 174.9 0.0 2.5e-51 174.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KXS97191.1 - 0.0025 17.6 0.4 0.0087 15.9 0.4 2.0 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KXS97191.1 - 0.051 13.6 0.0 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 Tyrosine phosphatase family HAMP_N3 PF18575.1 KXS97191.1 - 0.054 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 HAMP N-terminal domain 3 PTPlike_phytase PF14566.6 KXS97191.1 - 0.082 13.0 0.0 0.6 10.2 0.0 2.3 2 0 0 2 2 2 0 Inositol hexakisphosphate AKNA PF12443.8 KXS97193.1 - 0.014 16.1 0.0 0.026 15.2 0.0 1.4 1 0 0 1 1 1 0 AT-hook-containing transcription factor F-box-like PF12937.7 KXS97194.1 - 0.00038 20.3 0.0 0.0011 18.8 0.0 1.9 1 0 0 1 1 1 1 F-box-like GCIP PF13324.6 KXS97196.1 - 5e-41 141.0 0.8 5e-41 141.0 0.8 1.5 2 0 0 2 2 2 1 Grap2 and cyclin-D-interacting MscS_porin PF12795.7 KXS97196.1 - 0.0066 16.0 3.8 0.17 11.4 1.0 2.3 2 0 0 2 2 2 2 Mechanosensitive ion channel porin domain Mrx7 PF10906.8 KXS97197.1 - 9e-06 25.8 0.0 3e-05 24.2 0.0 1.9 1 1 0 1 1 1 1 MIOREX complex component 7 DUF1765 PF08578.10 KXS97198.1 - 2.9e-42 144.1 2.8 5.7e-42 143.1 2.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) Herpes_pp85 PF04637.12 KXS97198.1 - 2.9 6.2 5.5 5.3 5.3 5.5 1.3 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Pkinase PF00069.25 KXS97199.1 - 2.1e-51 174.8 0.0 5.9e-51 173.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS97199.1 - 1.5e-23 83.4 0.0 3.2e-23 82.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXS97199.1 - 0.0036 17.2 0.1 0.0036 17.2 0.1 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.22 KXS97199.1 - 0.0073 15.9 0.1 0.036 13.7 0.1 2.1 1 1 0 1 1 1 1 RIO1 family CorA PF01544.18 KXS97201.1 - 0.0013 18.2 0.0 0.0015 17.9 0.0 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Med9 PF07544.13 KXS97202.1 - 0.00028 20.9 1.9 0.00028 20.9 1.9 3.6 2 1 1 3 3 3 1 RNA polymerase II transcription mediator complex subunit 9 V_ATPase_I PF01496.19 KXS97202.1 - 0.0041 15.1 6.8 0.0056 14.7 6.8 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family ABC_tran_CTD PF16326.5 KXS97202.1 - 0.0049 17.1 1.9 0.0049 17.1 1.9 4.1 4 1 0 4 4 4 1 ABC transporter C-terminal domain Filament PF00038.21 KXS97202.1 - 0.0098 15.5 14.9 0.15 11.6 0.2 2.9 1 1 1 2 2 2 2 Intermediate filament protein DUF2968 PF11180.8 KXS97202.1 - 0.014 15.0 11.0 0.47 10.1 0.4 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2968) DHR10 PF18595.1 KXS97202.1 - 0.022 14.8 24.9 0.055 13.5 1.5 4.3 2 1 2 4 4 4 0 Designed helical repeat protein 10 domain DUF4407 PF14362.6 KXS97202.1 - 0.026 13.9 13.0 0.22 10.8 12.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Seryl_tRNA_N PF02403.22 KXS97202.1 - 0.041 14.1 17.8 0.12 12.6 0.9 3.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain LMBR1 PF04791.16 KXS97202.1 - 0.091 11.7 7.5 0.11 11.4 7.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Atg14 PF10186.9 KXS97202.1 - 0.098 11.7 14.0 0.22 10.6 14.1 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 GAS PF13851.6 KXS97202.1 - 0.14 11.5 16.7 0.039 13.3 6.3 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Baculo_PEP_C PF04513.12 KXS97202.1 - 0.25 11.4 4.5 1 9.4 0.1 2.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4201 PF13870.6 KXS97202.1 - 0.39 10.4 18.8 4.4 7.0 16.0 3.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) XhlA PF10779.9 KXS97202.1 - 0.41 10.9 20.8 1.2 9.4 1.0 4.5 4 1 0 4 4 4 0 Haemolysin XhlA JIP_LZII PF16471.5 KXS97202.1 - 0.53 10.5 15.1 1.9 8.7 0.8 3.9 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II CENP-F_leu_zip PF10473.9 KXS97202.1 - 0.54 10.3 26.1 0.06 13.4 12.6 3.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin_1 PF12718.7 KXS97202.1 - 0.6 10.3 21.0 1.4 9.0 2.8 3.0 1 1 2 3 3 3 0 Tropomyosin like ADIP PF11559.8 KXS97202.1 - 0.66 10.1 17.0 1.4 9.0 0.9 3.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding She9_MDM33 PF05546.11 KXS97202.1 - 0.83 9.4 11.7 0.89 9.3 9.0 2.4 1 1 0 2 2 2 0 She9 / Mdm33 family DUF1664 PF07889.12 KXS97202.1 - 0.89 9.6 14.7 13 5.8 0.9 3.6 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) CLZ PF16526.5 KXS97202.1 - 1.3 9.5 16.5 14 6.1 4.8 4.5 2 2 2 4 4 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels NPV_P10 PF05531.12 KXS97202.1 - 1.9 9.0 12.9 5.1 7.6 1.8 3.9 3 1 1 4 4 3 0 Nucleopolyhedrovirus P10 protein HALZ PF02183.18 KXS97202.1 - 1.9 8.7 9.1 28 5.0 0.1 3.6 3 0 0 3 3 3 0 Homeobox associated leucine zipper Lectin_N PF03954.14 KXS97202.1 - 2 8.1 5.3 0.92 9.3 1.4 2.2 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Syntaxin-6_N PF09177.11 KXS97202.1 - 2.1 8.9 14.1 5 7.8 3.9 3.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Fzo_mitofusin PF04799.13 KXS97202.1 - 2.6 7.6 8.6 15 5.1 1.4 3.3 1 1 3 4 4 4 0 fzo-like conserved region SlyX PF04102.12 KXS97202.1 - 3.5 8.3 12.9 8.1 7.1 0.2 4.4 3 1 2 5 5 5 0 SlyX FlaC_arch PF05377.11 KXS97202.1 - 3.9 7.9 20.2 1.2 9.6 1.2 4.5 4 2 1 5 5 3 0 Flagella accessory protein C (FlaC) CENP-K PF11802.8 KXS97202.1 - 4.6 6.7 15.5 3.6 7.1 13.6 1.7 1 1 0 1 1 1 0 Centromere-associated protein K Cep57_CLD_2 PF14197.6 KXS97202.1 - 6.1 7.0 13.4 1.2 9.2 0.1 3.8 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 DUF2203 PF09969.9 KXS97202.1 - 6.4 7.5 12.6 1.4 9.6 0.3 3.3 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) CENP-Q PF13094.6 KXS97202.1 - 6.7 6.9 16.5 0.14 12.3 3.1 3.0 2 1 1 3 3 2 0 CENP-Q, a CENPA-CAD centromere complex subunit bZIP_2 PF07716.15 KXS97202.1 - 7.9 6.7 10.9 9.9 6.3 2.2 3.8 3 0 0 3 3 3 0 Basic region leucine zipper DUF4446 PF14584.6 KXS97202.1 - 8.1 6.4 11.5 2 8.4 2.3 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) Swi5 PF07061.11 KXS97202.1 - 9.3 6.4 13.0 11 6.2 0.8 3.7 2 1 0 3 3 3 0 Swi5 DUF16 PF01519.16 KXS97205.1 - 0.0037 17.7 18.3 2.4 8.7 4.7 4.3 1 1 2 4 4 4 1 Protein of unknown function DUF16 HALZ PF02183.18 KXS97205.1 - 0.0038 17.4 2.1 1.2 9.4 0.3 2.8 2 0 0 2 2 2 2 Homeobox associated leucine zipper DUF1664 PF07889.12 KXS97205.1 - 0.013 15.5 17.0 2 8.5 0.8 5.1 1 1 5 6 6 6 0 Protein of unknown function (DUF1664) Gp-FAR-1 PF05823.12 KXS97205.1 - 0.015 15.7 5.2 1 9.7 0.1 3.7 2 1 2 4 4 4 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) FlaC_arch PF05377.11 KXS97205.1 - 0.077 13.4 15.1 0.31 11.4 1.2 5.8 4 2 3 7 7 7 0 Flagella accessory protein C (FlaC) DUF4618 PF15397.6 KXS97205.1 - 0.22 10.9 19.0 0.39 10.1 6.0 3.4 2 2 1 3 3 3 0 Domain of unknown function (DUF4618) bZIP_1 PF00170.21 KXS97205.1 - 0.85 9.8 16.9 0.91 9.7 0.1 4.6 5 2 2 7 7 7 0 bZIP transcription factor Med15_fungi PF05397.12 KXS97205.1 - 2.8 8.2 7.6 31 4.9 0.3 3.6 4 0 0 4 4 4 0 Mediator complex subunit 15 XhlA PF10779.9 KXS97205.1 - 2.8 8.2 16.3 14 6.0 0.7 5.9 4 2 4 8 8 8 0 Haemolysin XhlA Vac_Fusion PF02346.16 KXS97205.1 - 4.6 6.9 10.8 13 5.5 0.3 4.7 4 2 1 5 5 5 0 Chordopoxvirus multifunctional envelope protein A27 MFS_1 PF07690.16 KXS97206.1 - 9.8e-30 103.7 10.3 1.2e-29 103.4 10.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS97206.1 - 1.8e-05 23.8 4.6 1.8e-05 23.8 4.6 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter HMG_CoA_synt_C PF08540.10 KXS97208.1 - 1.5e-106 356.1 2.9 2e-106 355.7 2.9 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KXS97208.1 - 1.3e-96 321.5 0.1 2.3e-96 320.7 0.1 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal KGG PF10685.9 KXS97209.1 - 8.1e-10 38.7 9.3 4.1e-08 33.2 0.0 4.3 4 0 0 4 4 4 2 Stress-induced bacterial acidophilic repeat motif Toxin_17 PF08086.11 KXS97209.1 - 0.0067 16.7 0.2 42 4.5 0.0 3.2 3 0 0 3 3 3 3 Ergtoxin family Minor_capsid_3 PF12691.7 KXS97209.1 - 0.099 13.0 1.5 23 5.3 0.0 2.9 1 1 2 3 3 3 0 Minor capsid protein from bacteriophage CCDC92 PF14916.6 KXS97210.1 - 0.00095 18.9 2.7 0.0083 15.9 0.2 3.0 2 1 0 2 2 2 1 Coiled-coil domain of unknown function TolA_bind_tri PF16331.5 KXS97210.1 - 0.0045 17.0 0.7 0.0045 17.0 0.7 3.3 3 1 0 4 4 4 1 TolA binding protein trimerisation Csm1_N PF18504.1 KXS97210.1 - 0.028 14.8 1.0 0.028 14.8 1.0 3.3 3 1 0 3 3 3 0 Csm1 N-terminal domain FlaC_arch PF05377.11 KXS97210.1 - 0.051 14.0 5.7 8.2 6.9 0.4 4.2 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) PFO_beta_C PF12367.8 KXS97210.1 - 0.16 12.1 0.0 0.71 10.1 0.0 2.1 2 0 0 2 2 2 0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal NPV_P10 PF05531.12 KXS97210.1 - 0.2 12.1 3.8 3.1 8.3 0.5 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein hDGE_amylase PF14701.6 KXS97210.1 - 0.3 10.1 5.2 0.27 10.3 4.4 1.3 1 1 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Lzipper-MIP1 PF14389.6 KXS97210.1 - 0.33 11.3 7.7 5.5 7.4 0.1 3.8 3 1 1 4 4 4 0 Leucine-zipper of ternary complex factor MIP1 Bap31_Bap29_C PF18035.1 KXS97210.1 - 1.4 9.0 8.9 4.1 7.5 0.4 3.6 2 1 1 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain BLOC1_2 PF10046.9 KXS97210.1 - 2.3 8.6 10.8 2.4 8.5 2.7 3.3 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fez1 PF06818.15 KXS97210.1 - 4.2 7.8 15.7 0.8 10.1 8.6 2.1 1 1 1 2 2 2 0 Fez1 Exonuc_VII_L PF02601.15 KXS97210.1 - 6.9 6.1 13.8 14 5.1 13.8 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit CP12 PF02672.15 KXS97210.1 - 7.6 7.4 8.4 94 3.9 0.2 3.7 2 1 2 4 4 4 0 CP12 domain MRP-S31 PF15433.6 KXS97210.1 - 8.4 6.0 11.8 11 5.6 11.8 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 CCDC-167 PF15188.6 KXS97210.1 - 8.8 6.7 9.3 1.6 9.2 3.0 2.7 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 zinc_ribbon_10 PF10058.9 KXS97212.1 - 0.073 12.8 0.2 0.15 11.8 0.2 1.5 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein CCDC106 PF15794.5 KXS97212.1 - 0.57 9.8 3.6 0.94 9.1 3.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 FAM110_C PF14160.6 KXS97212.1 - 0.99 10.5 3.5 3.5 8.7 3.5 2.0 1 1 0 1 1 1 0 Centrosome-associated C terminus Polyketide_cyc2 PF10604.9 KXS97213.1 - 5e-08 33.3 0.0 5.9e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport CFEM PF05730.11 KXS97215.1 - 0.00066 19.7 13.0 0.0011 19.0 13.0 1.3 1 0 0 1 1 1 1 CFEM domain DUF5137 PF17220.3 KXS97215.1 - 0.0035 18.2 1.2 0.026 15.4 0.3 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF5137) FAD_binding_3 PF01494.19 KXS97216.1 - 3.4e-13 49.6 0.0 8.3e-13 48.3 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXS97216.1 - 2.2e-09 37.0 0.0 1.5e-08 34.3 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXS97216.1 - 3.2e-09 36.8 0.7 1.1e-06 28.5 0.4 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXS97216.1 - 9.7e-08 32.1 0.0 3e-07 30.5 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXS97216.1 - 1.8e-05 24.0 0.3 2.9e-05 23.3 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KXS97216.1 - 8.6e-05 23.0 1.7 0.00084 19.9 0.2 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXS97216.1 - 0.00016 20.9 0.0 0.00021 20.5 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 KXS97216.1 - 0.00054 19.4 0.0 0.00085 18.7 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase ApbA PF02558.16 KXS97216.1 - 0.00056 19.6 0.0 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 KXS97216.1 - 0.001 17.9 0.1 0.0015 17.3 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 KXS97216.1 - 0.0011 18.5 0.0 0.0016 17.9 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXS97216.1 - 0.0016 17.8 0.0 0.0044 16.3 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXS97216.1 - 0.003 16.5 0.1 0.092 11.6 0.0 2.2 2 0 0 2 2 2 1 Tryptophan halogenase 3HCDH_N PF02737.18 KXS97216.1 - 0.0038 17.1 0.0 0.0063 16.4 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KXS97216.1 - 0.012 15.0 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KXS97216.1 - 0.016 14.4 0.0 0.041 13.1 0.0 1.6 1 0 0 1 1 1 0 Thi4 family NAD_Gly3P_dh_N PF01210.23 KXS97216.1 - 0.022 14.7 0.0 0.05 13.6 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus SE PF08491.10 KXS97216.1 - 0.031 13.3 0.0 0.051 12.6 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase NAD_binding_9 PF13454.6 KXS97216.1 - 0.084 12.9 0.1 1.4 8.9 0.0 2.6 3 0 0 3 3 2 0 FAD-NAD(P)-binding NAD_binding_2 PF03446.15 KXS97216.1 - 0.091 12.9 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase FMO-like PF00743.19 KXS97216.1 - 0.13 10.7 0.0 0.23 9.9 0.0 1.3 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like UDPG_MGDP_dh_N PF03721.14 KXS97216.1 - 0.17 11.4 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PPL5 PF18168.1 KXS97218.1 - 0.2 10.9 3.5 0.25 10.6 3.5 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Nop14 PF04147.12 KXS97218.1 - 0.24 9.6 16.7 0.25 9.5 16.7 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KXS97218.1 - 0.39 9.0 12.4 0.38 9.0 12.4 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF4820 PF16091.5 KXS97218.1 - 1.3 8.3 7.1 2.1 7.7 7.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Presenilin PF01080.17 KXS97218.1 - 2.2 7.0 8.8 2.3 6.9 8.8 1.0 1 0 0 1 1 1 0 Presenilin SpoIIIAH PF12685.7 KXS97218.1 - 2.2 8.1 11.8 2.9 7.7 11.8 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein RR_TM4-6 PF06459.12 KXS97218.1 - 2.2 8.0 10.3 2.6 7.8 10.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NPR3 PF03666.13 KXS97218.1 - 4.2 6.0 10.9 4.6 5.9 10.9 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4746 PF15928.5 KXS97218.1 - 4.8 6.5 9.3 5.9 6.2 9.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF913 PF06025.12 KXS97218.1 - 4.8 6.1 4.8 5.9 5.8 4.8 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Zip PF02535.22 KXS97218.1 - 5.1 6.2 6.6 5.6 6.1 6.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Nucleo_P87 PF07267.11 KXS97218.1 - 6.6 5.5 8.1 7.7 5.2 8.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Syndecan PF01034.20 KXS97221.1 - 0.1 12.5 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 Syndecan domain TP2 PF01254.18 KXS97222.1 - 1.3 9.6 9.6 5.1 7.7 9.6 1.8 1 1 0 1 1 1 0 Nuclear transition protein 2 Efg1 PF10153.9 KXS97228.1 - 3.3 8.1 9.4 0.16 12.3 1.8 2.8 3 0 0 3 3 3 0 rRNA-processing protein Efg1 ThiC-associated PF13667.6 KXS97229.1 - 0.0019 18.0 0.5 2 8.3 0.0 3.3 1 1 2 3 3 3 3 ThiC-associated domain DUF802 PF05650.11 KXS97230.1 - 0.66 10.5 3.6 0.45 11.0 1.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF802) ADIP PF11559.8 KXS97232.1 - 3.2e-06 27.3 9.9 4.7e-06 26.8 9.9 1.2 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Filament PF00038.21 KXS97232.1 - 2.3e-05 24.2 6.2 3.1e-05 23.7 6.2 1.1 1 0 0 1 1 1 1 Intermediate filament protein LPP PF04728.13 KXS97232.1 - 0.00017 21.9 5.0 0.0076 16.6 1.5 2.8 1 1 1 2 2 2 1 Lipoprotein leucine-zipper Spc7 PF08317.11 KXS97232.1 - 0.00029 19.8 5.2 0.00046 19.2 5.2 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein TMF_TATA_bd PF12325.8 KXS97232.1 - 0.00056 20.1 4.9 0.0012 19.0 4.9 1.5 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding zf-C4H2 PF10146.9 KXS97232.1 - 0.0011 19.3 3.7 0.0019 18.6 3.7 1.3 1 0 0 1 1 1 1 Zinc finger-containing protein PI3K_P85_iSH2 PF16454.5 KXS97232.1 - 0.0054 16.3 4.7 0.0094 15.6 4.7 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain APG6_N PF17675.1 KXS97232.1 - 0.008 16.7 9.3 0.015 15.9 9.3 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region DUF812 PF05667.11 KXS97232.1 - 0.01 14.7 5.2 0.017 14.1 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) KASH_CCD PF14662.6 KXS97232.1 - 0.012 15.4 6.2 0.019 14.8 6.2 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH HAP1_N PF04849.13 KXS97232.1 - 0.012 14.8 4.6 0.023 13.9 4.6 1.4 1 0 0 1 1 1 0 HAP1 N-terminal conserved region HMMR_N PF15905.5 KXS97232.1 - 0.013 15.0 8.0 0.021 14.3 8.0 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Golgin_A5 PF09787.9 KXS97232.1 - 0.02 14.4 6.8 0.033 13.7 6.8 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF3584 PF12128.8 KXS97232.1 - 0.022 12.3 7.6 0.028 12.0 7.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) PKcGMP_CC PF16808.5 KXS97232.1 - 0.022 14.6 6.0 0.053 13.4 0.8 2.5 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF724 PF05266.14 KXS97232.1 - 0.024 14.5 4.4 0.038 13.8 4.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Atg14 PF10186.9 KXS97232.1 - 0.024 13.7 5.4 0.037 13.1 5.4 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fez1 PF06818.15 KXS97232.1 - 0.027 14.9 4.9 0.044 14.2 4.9 1.2 1 0 0 1 1 1 0 Fez1 Ax_dynein_light PF10211.9 KXS97232.1 - 0.035 14.1 5.8 0.087 12.8 5.8 1.6 2 0 0 2 2 1 0 Axonemal dynein light chain FAM76 PF16046.5 KXS97232.1 - 0.041 13.3 5.5 0.063 12.6 5.5 1.2 1 0 0 1 1 1 0 FAM76 protein DUF2205 PF10224.9 KXS97232.1 - 0.059 13.4 4.4 0.1 12.6 2.2 2.4 1 1 1 2 2 2 0 Short coiled-coil protein CEP209_CC5 PF16574.5 KXS97232.1 - 0.077 13.2 7.1 0.15 12.3 7.1 1.4 1 0 0 1 1 1 0 Coiled-coil region of centrosome protein CE290 PspA_IM30 PF04012.12 KXS97232.1 - 0.077 12.6 9.0 0.021 14.4 5.3 1.7 1 1 1 2 2 2 0 PspA/IM30 family Mod_r PF07200.13 KXS97232.1 - 0.083 13.0 5.4 0.17 12.0 5.4 1.6 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein AAA_13 PF13166.6 KXS97232.1 - 0.095 11.3 4.2 0.14 10.7 4.2 1.2 1 0 0 1 1 1 0 AAA domain HemX PF04375.14 KXS97232.1 - 0.097 11.9 7.1 8.9 5.5 6.7 2.4 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Tropomyosin PF00261.20 KXS97232.1 - 0.11 11.9 9.2 0.15 11.4 9.2 1.2 1 0 0 1 1 1 0 Tropomyosin KELK PF15796.5 KXS97232.1 - 0.15 12.6 5.8 0.11 13.0 4.0 1.7 1 1 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase ATG16 PF08614.11 KXS97232.1 - 0.16 12.2 11.8 0.16 12.2 10.9 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Allexi_40kDa PF05549.11 KXS97232.1 - 0.17 11.4 1.0 0.34 10.4 1.0 1.5 1 1 0 1 1 1 0 Allexivirus 40kDa protein Leu_zip PF15294.6 KXS97232.1 - 0.18 11.3 5.4 0.28 10.7 5.4 1.2 1 0 0 1 1 1 0 Leucine zipper DUF4407 PF14362.6 KXS97232.1 - 0.18 11.1 5.8 0.31 10.4 5.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ZapB PF06005.12 KXS97232.1 - 0.21 12.0 6.7 0.67 10.4 2.7 2.7 1 1 1 2 2 2 0 Cell division protein ZapB GCN5L1 PF06320.13 KXS97232.1 - 0.23 11.6 6.4 0.29 11.3 5.2 1.7 2 0 0 2 2 1 0 GCN5-like protein 1 (GCN5L1) TMF_DNA_bd PF12329.8 KXS97232.1 - 0.25 11.4 9.2 0.063 13.3 2.6 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Mito_fiss_reg PF05308.11 KXS97232.1 - 0.32 11.0 11.0 0.076 13.1 7.6 1.7 1 1 1 2 2 2 0 Mitochondrial fission regulator DUF1465 PF07323.12 KXS97232.1 - 0.33 10.8 4.5 0.58 10.0 4.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) FlxA PF14282.6 KXS97232.1 - 0.34 10.9 11.4 2.5 8.1 11.4 2.2 1 1 0 1 1 1 0 FlxA-like protein Jnk-SapK_ap_N PF09744.9 KXS97232.1 - 0.37 11.0 10.1 9.3 6.5 10.2 2.2 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 DivIC PF04977.15 KXS97232.1 - 0.43 10.4 10.8 4.9 7.0 7.7 2.8 1 1 2 3 3 3 0 Septum formation initiator BLOC1_2 PF10046.9 KXS97232.1 - 0.44 10.9 3.2 0.93 9.8 3.2 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TPR_MLP1_2 PF07926.12 KXS97232.1 - 0.45 10.6 12.1 12 6.0 12.2 2.2 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein BST2 PF16716.5 KXS97232.1 - 0.46 11.1 7.6 0.078 13.6 1.8 2.3 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 DUF4972 PF16342.5 KXS97232.1 - 0.53 10.0 3.8 1.1 8.9 3.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4972) YabA PF06156.13 KXS97232.1 - 0.57 10.8 2.3 1.3 9.7 2.3 1.6 1 0 0 1 1 1 0 Initiation control protein YabA UPF0242 PF06785.11 KXS97232.1 - 0.77 9.8 7.7 1.3 9.1 7.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF1664 PF07889.12 KXS97232.1 - 0.8 9.8 3.0 1.7 8.7 2.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Prominin PF05478.11 KXS97232.1 - 0.82 7.6 2.1 1.2 7.0 2.1 1.2 1 0 0 1 1 1 0 Prominin DUF3450 PF11932.8 KXS97232.1 - 0.84 8.9 10.4 2 7.7 10.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) KLRAQ PF10205.9 KXS97232.1 - 1.1 9.6 6.2 8.8 6.6 5.1 2.2 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein DUF4200 PF13863.6 KXS97232.1 - 1.1 9.6 11.9 93 3.4 11.9 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) TMPIT PF07851.13 KXS97232.1 - 1.6 7.9 4.3 2.5 7.3 4.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein SlyX PF04102.12 KXS97232.1 - 2.6 8.7 7.4 91 3.8 7.0 2.8 1 1 1 2 2 2 0 SlyX GrpE PF01025.19 KXS97232.1 - 3.2 7.4 9.6 5.5 6.6 0.9 2.3 1 1 1 2 2 2 0 GrpE Spc24 PF08286.11 KXS97232.1 - 5.8 7.2 9.0 16 5.8 2.7 2.5 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF4337 PF14235.6 KXS97232.1 - 8.5 6.5 7.9 15 5.6 7.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Urease_gamma PF00547.18 KXS97236.1 - 0.093 13.1 0.0 0.33 11.3 0.0 1.9 2 0 0 2 2 2 0 Urease, gamma subunit HMG_box PF00505.19 KXS97242.1 - 7.6e-20 71.1 0.5 1.6e-19 70.1 0.5 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KXS97242.1 - 1.8e-05 25.2 0.2 3.9e-05 24.2 0.2 1.5 1 0 0 1 1 1 1 HMG-box domain Abhydrolase_2 PF02230.16 KXS97243.1 - 2.2e-26 93.0 0.0 4.2e-26 92.1 0.0 1.4 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KXS97243.1 - 0.031 13.5 0.0 0.48 9.7 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 EpmC PF04315.12 KXS97243.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Elongation factor P hydroxylase FSH1 PF03959.13 KXS97243.1 - 0.16 11.6 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Cutinase PF01083.22 KXS97243.1 - 0.22 11.5 0.0 0.38 10.7 0.0 1.4 1 0 0 1 1 1 0 Cutinase COX6A PF02046.15 KXS97244.1 - 1.6e-48 163.9 0.8 3e-48 162.9 0.8 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Hydrolase_6 PF13344.6 KXS97244.1 - 3.5e-21 75.2 0.0 7.8e-21 74.1 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXS97244.1 - 2.8e-19 69.0 0.0 3.3e-18 65.5 0.0 2.4 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 KXS97244.1 - 5.4e-05 23.6 0.0 0.075 13.3 0.0 2.6 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KXS97244.1 - 0.022 14.8 0.0 8 6.5 0.0 2.5 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Exo_endo_phos PF03372.23 KXS97245.1 - 1.4e-10 41.1 0.2 2.8e-10 40.1 0.2 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 KXS97245.1 - 0.0069 16.4 7.7 0.02 15.0 7.7 1.8 1 1 0 1 1 1 1 GRF zinc finger Nyv1_N PF09426.10 KXS97245.1 - 0.19 11.7 0.0 0.33 11.0 0.0 1.3 1 0 0 1 1 1 0 Vacuolar R-SNARE Nyv1 N terminal PRP21_like_P PF12230.8 KXS97246.1 - 1.9e-48 165.2 10.7 2.5e-48 164.8 9.6 1.8 2 1 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 KXS97246.1 - 1.6e-29 101.6 6.2 2.5e-14 53.0 0.1 3.2 3 0 0 3 3 3 2 Surp module zf_UBZ PF18439.1 KXS97246.1 - 0.0024 17.4 0.5 0.0057 16.2 0.5 1.7 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger DUF3328 PF11807.8 KXS97250.1 - 1.5e-21 77.2 0.1 2.2e-21 76.7 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Homeodomain PF00046.29 KXS97251.1 - 0.0031 17.3 0.2 0.02 14.7 0.0 2.3 2 0 0 2 2 2 1 Homeodomain SAICAR_synt PF01259.18 KXS97252.1 - 1.6e-101 339.2 0.0 1.9e-101 338.9 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase TPP_enzyme_N PF02776.18 KXS97253.1 - 1.4e-35 122.4 0.1 2.9e-35 121.4 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KXS97253.1 - 4.4e-23 81.5 0.0 1.1e-22 80.2 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KXS97253.1 - 1.8e-17 63.5 0.0 4.6e-17 62.2 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Dmd PF17587.2 KXS97253.1 - 0.017 15.5 0.0 0.098 13.0 0.0 2.0 2 0 0 2 2 2 0 Discriminator of mRNA degradation F-box-like PF12937.7 KXS97254.1 - 1.3e-09 37.8 1.9 3.1e-09 36.6 1.9 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS97254.1 - 0.0011 18.8 0.5 0.012 15.5 0.0 2.5 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.7 KXS97254.1 - 0.048 14.1 9.9 24 5.5 1.4 5.6 4 3 2 6 6 6 0 Leucine Rich repeats (2 copies) PALP PF00291.25 KXS97255.1 - 4.2e-34 118.3 0.0 4.7e-34 118.1 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF212 PF02681.14 KXS97255.1 - 0.071 13.2 0.1 0.23 11.6 0.0 1.7 2 0 0 2 2 2 0 Divergent PAP2 family DUF3636 PF12331.8 KXS97256.1 - 2.2e-44 150.9 0.3 3.9e-44 150.1 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) LCD1 PF09798.9 KXS97256.1 - 7e-07 28.2 0.6 0.0088 14.6 0.0 2.3 2 0 0 2 2 2 2 DNA damage checkpoint protein DivIC PF04977.15 KXS97256.1 - 3 7.7 12.5 0.45 10.3 2.2 2.5 2 0 0 2 2 2 0 Septum formation initiator Abhydrolase_1 PF00561.20 KXS97257.1 - 4.7e-18 65.8 0.4 1.2e-17 64.4 0.4 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXS97257.1 - 5.9e-12 46.6 0.1 2.1e-11 44.9 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXS97257.1 - 1.4e-05 24.5 0.0 0.00099 18.4 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 CTP_transf_1 PF01148.20 KXS97258.1 - 2.2e-79 267.0 25.2 2.7e-79 266.7 25.2 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family AA_permease_C PF13906.6 KXS97258.1 - 3 8.0 13.6 1.2 9.2 0.3 4.2 4 0 0 4 4 4 0 C-terminus of AA_permease ERG4_ERG24 PF01222.17 KXS97259.1 - 1.6e-145 485.1 26.1 1.9e-145 484.9 26.1 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Phosphorylase PF00343.20 KXS97260.1 - 0 1066.6 0.0 0 1066.4 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Sulfotransfer_4 PF17784.1 KXS97261.1 - 0.013 15.3 0.1 0.014 15.2 0.1 1.0 1 0 0 1 1 1 0 Sulfotransferase domain EIF_2_alpha PF07541.12 KXS97262.1 - 1.4e-37 128.3 0.1 3.2e-37 127.2 0.1 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 KXS97262.1 - 1.3e-13 51.1 0.7 2.7e-13 50.0 0.7 1.6 1 0 0 1 1 1 1 S1 RNA binding domain ANAPC5 PF12862.7 KXS97263.1 - 1.2e-29 102.2 5.0 1.4e-29 102.0 3.0 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_7 PF13176.6 KXS97263.1 - 0.00012 21.8 4.3 1.1 9.5 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 KXS97263.1 - 0.0076 16.1 1.2 0.092 12.6 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXS97263.1 - 0.0077 16.5 0.9 0.0077 16.5 0.9 5.6 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXS97263.1 - 0.071 13.6 6.3 18 5.9 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXS97263.1 - 1 9.8 0.0 1 9.8 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXS97263.1 - 3.5 8.7 8.9 48 5.2 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Sulfotransfer_4 PF17784.1 KXS97264.1 - 4.9e-10 39.6 0.0 5.7e-10 39.4 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KXS97264.1 - 0.0037 17.7 0.1 0.0049 17.3 0.1 1.5 1 1 0 1 1 1 1 Sulfotransferase family ADH_zinc_N PF00107.26 KXS97265.1 - 2.9e-18 66.1 0.3 1e-17 64.3 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXS97265.1 - 3.3e-07 30.0 0.3 5.6e-07 29.3 0.2 1.3 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus UDPG_MGDP_dh_N PF03721.14 KXS97265.1 - 0.01 15.4 0.4 0.017 14.7 0.3 1.4 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ADH_zinc_N_2 PF13602.6 KXS97265.1 - 0.021 15.9 0.0 0.038 15.0 0.0 1.4 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Trp_halogenase PF04820.14 KXS97265.1 - 0.065 12.1 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase ADH_zinc_N PF00107.26 KXS97266.1 - 2.9e-18 66.1 0.3 1e-17 64.3 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXS97266.1 - 3.3e-07 30.0 0.3 5.6e-07 29.3 0.2 1.3 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus UDPG_MGDP_dh_N PF03721.14 KXS97266.1 - 0.01 15.4 0.4 0.017 14.7 0.3 1.4 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ADH_zinc_N_2 PF13602.6 KXS97266.1 - 0.021 15.9 0.0 0.038 15.0 0.0 1.4 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Trp_halogenase PF04820.14 KXS97266.1 - 0.065 12.1 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase ADH_zinc_N PF00107.26 KXS97267.1 - 3.1e-18 66.0 0.3 1.1e-17 64.3 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXS97267.1 - 3.3e-07 30.0 0.3 5.4e-07 29.3 0.2 1.3 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus UDPG_MGDP_dh_N PF03721.14 KXS97267.1 - 0.01 15.4 0.4 0.017 14.7 0.3 1.4 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ADH_zinc_N_2 PF13602.6 KXS97267.1 - 0.021 15.9 0.0 0.039 15.0 0.0 1.4 1 1 0 1 1 1 0 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KXS97267.1 - 0.061 12.6 0.1 0.078 12.3 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 KXS97267.1 - 0.066 12.1 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Kinesin PF00225.23 KXS97278.1 - 4.1e-92 308.7 0.0 4.1e-92 308.7 0.0 3.6 4 0 0 4 4 4 1 Kinesin motor domain Microtub_bd PF16796.5 KXS97278.1 - 1.2e-20 73.9 0.3 1.8e-16 60.4 0.0 4.3 3 1 1 4 4 4 2 Microtubule binding FAM184 PF15665.5 KXS97278.1 - 0.00024 20.9 21.8 0.00024 20.9 21.8 9.4 6 3 2 9 9 9 3 Family with sequence similarity 184, A and B TMF_DNA_bd PF12329.8 KXS97278.1 - 0.0033 17.4 8.1 0.0033 17.4 8.1 15.0 12 4 6 18 18 18 3 TATA element modulatory factor 1 DNA binding Phage_sheath_1C PF17482.2 KXS97278.1 - 0.49 10.4 3.9 0.45 10.5 1.5 2.2 2 0 0 2 2 2 0 Phage tail sheath C-terminal domain LIF_OSM PF01291.17 KXS97278.1 - 1.2 9.3 6.9 0.34 11.0 0.1 3.6 3 0 0 3 3 3 0 LIF / OSM family Glyco_hydro_43 PF04616.14 KXS97281.1 - 2.7e-34 118.8 1.4 3.3e-34 118.5 1.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Amidoligase_2 PF12224.8 KXS97282.1 - 1.3e-16 61.0 0.0 2.6e-11 43.7 0.0 2.3 2 0 0 2 2 2 2 Putative amidoligase enzyme Mito_carr PF00153.27 KXS97284.1 - 8.5e-61 201.9 5.3 6e-20 71.0 0.0 4.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Smg4_UPF3 PF03467.15 KXS97285.1 - 1.9e-36 125.7 0.1 1.9e-36 125.7 0.1 2.4 2 0 0 2 2 2 1 Smg-4/UPF3 family RRM_1 PF00076.22 KXS97285.1 - 0.057 13.2 0.0 0.24 11.3 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDK5_activator PF03261.15 KXS97285.1 - 0.88 9.0 8.8 1.4 8.4 8.8 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein RPA_C PF08784.11 KXS97286.1 - 2.2e-18 66.8 0.7 2.2e-18 66.8 0.7 2.0 2 1 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 KXS97286.1 - 7.8e-08 32.2 0.1 1.3e-07 31.5 0.1 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain HTH_36 PF13730.6 KXS97286.1 - 0.17 11.9 0.0 0.36 10.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain FSH1 PF03959.13 KXS97287.1 - 3.8e-52 177.0 0.0 4.4e-52 176.8 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 KXS97287.1 - 2.3e-05 24.3 0.6 0.25 11.1 1.5 3.1 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 KXS97287.1 - 0.0022 17.7 0.2 0.37 10.4 0.0 2.9 3 0 0 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXS97287.1 - 0.44 11.1 2.7 3.8 8.0 1.1 2.1 1 1 1 2 2 2 0 Alpha/beta hydrolase family MT-A70 PF05063.14 KXS97288.1 - 3.5e-29 101.9 0.2 3.3e-27 95.5 0.2 2.2 1 1 0 1 1 1 1 MT-A70 Coat_F PF07875.12 KXS97288.1 - 0.027 14.7 0.0 0.069 13.4 0.0 1.6 1 0 0 1 1 1 0 Coat F domain Cons_hypoth95 PF03602.15 KXS97288.1 - 0.19 11.3 0.0 0.46 10.1 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical protein 95 RTA1 PF04479.13 KXS97289.1 - 9.1e-37 126.7 2.8 1.3e-36 126.1 2.8 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF2754 PF10953.8 KXS97289.1 - 0.12 12.7 0.9 0.4 11.0 0.9 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2754) 2TM PF13239.6 KXS97289.1 - 0.15 12.4 5.6 11 6.4 4.1 2.5 2 0 0 2 2 2 0 2TM domain HET PF06985.11 KXS97291.1 - 5.1e-31 108.0 0.2 1.2e-30 106.8 0.2 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_43 PF04616.14 KXS97292.1 - 9.8e-22 77.6 0.1 9e-21 74.4 0.1 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Sel1 PF08238.12 KXS97292.1 - 0.0097 16.6 0.1 0.035 14.8 0.1 2.0 1 0 0 1 1 1 1 Sel1 repeat DEAD PF00270.29 KXS97293.1 - 2.5e-50 170.7 0.0 6.5e-49 166.1 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase DBP10CT PF08147.12 KXS97293.1 - 3.8e-22 78.3 6.8 3.8e-22 78.3 6.8 2.6 3 0 0 3 3 3 1 DBP10CT (NUC160) domain Helicase_C PF00271.31 KXS97293.1 - 4.8e-22 78.4 0.0 1.6e-21 76.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXS97293.1 - 5.7e-08 33.0 0.6 1.3e-06 28.5 0.0 3.0 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit HDPD PF02924.14 KXS97293.1 - 0.034 14.2 1.0 0.27 11.3 0.0 2.5 2 0 0 2 2 2 0 Bacteriophage lambda head decoration protein D TRI12 PF06609.13 KXS97294.1 - 1.6e-29 102.8 28.5 2.1e-29 102.5 28.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KXS97294.1 - 3.9e-18 65.5 53.8 3.9e-18 65.5 53.8 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS97294.1 - 2.2e-09 36.7 13.4 2.2e-09 36.7 13.4 3.3 3 1 1 4 4 4 1 Sugar (and other) transporter BatA PF07584.11 KXS97294.1 - 0.065 13.6 0.5 0.32 11.4 0.5 2.2 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal DUF202 PF02656.15 KXS97295.1 - 4.4e-17 62.3 2.4 2.3e-16 60.0 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) STE2 PF02116.15 KXS97295.1 - 0.022 14.1 1.6 0.028 13.7 1.6 1.1 1 0 0 1 1 1 0 Fungal pheromone mating factor STE2 GPCR COX4_pro_2 PF07835.12 KXS97295.1 - 1.4 9.0 4.8 4.5 7.5 0.0 2.3 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV PRMT5_TIM PF17285.2 KXS97296.1 - 9.7e-68 228.1 0.0 1.3e-67 227.7 0.0 1.1 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 KXS97296.1 - 6.9e-61 205.1 0.0 1.1e-60 204.4 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 KXS97296.1 - 4.3e-55 186.3 0.0 8.4e-55 185.4 0.0 1.5 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Ank_2 PF12796.7 KXS97297.1 - 3.7e-47 158.8 2.3 3.1e-08 34.1 0.0 6.6 6 0 0 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS97297.1 - 1.7e-38 130.5 7.1 1.3e-08 35.2 0.0 10.4 7 4 5 12 12 12 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS97297.1 - 1.9e-30 104.5 13.5 1.3e-05 25.4 0.0 9.4 6 4 4 11 11 11 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS97297.1 - 2.7e-27 91.8 12.4 0.0085 16.5 0.0 13.9 14 0 0 14 14 14 7 Ankyrin repeat Ank PF00023.30 KXS97297.1 - 2.3e-26 91.1 16.4 0.0085 16.5 0.0 14.4 13 2 0 13 13 13 6 Ankyrin repeat Peptidase_C48 PF02902.19 KXS97298.1 - 9.2e-14 51.8 0.0 2.2e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Macoilin PF09726.9 KXS97298.1 - 0.017 13.7 11.7 0.023 13.3 11.7 1.2 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 KXS97298.1 - 0.84 8.3 15.9 1.7 7.3 15.9 1.4 1 0 0 1 1 1 0 Presenilin DUF966 PF06136.13 KXS97298.1 - 2.9 7.5 12.6 8.2 6.0 12.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF966) AA_permease PF00324.21 KXS97299.1 - 3.2e-141 471.2 37.9 3.6e-141 471.0 37.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXS97299.1 - 1.3e-34 119.7 41.8 1.8e-34 119.4 41.8 1.0 1 0 0 1 1 1 1 Amino acid permease adh_short PF00106.25 KXS97300.1 - 9.4e-15 54.6 0.0 5.1e-11 42.4 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS97300.1 - 1.3e-07 31.5 0.0 0.0089 15.6 0.0 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS97300.1 - 0.00061 19.7 0.0 0.00096 19.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS97300.1 - 0.0011 18.5 0.0 0.003 17.0 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KXS97300.1 - 0.0056 15.9 0.0 0.008 15.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KXS97301.1 - 9.4e-15 54.6 0.0 5.1e-11 42.4 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS97301.1 - 1.3e-07 31.5 0.0 0.0089 15.6 0.0 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS97301.1 - 0.00061 19.7 0.0 0.00096 19.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS97301.1 - 0.0011 18.5 0.0 0.003 17.0 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KXS97301.1 - 0.0056 15.9 0.0 0.008 15.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RRM_1 PF00076.22 KXS97304.1 - 2.4e-21 75.3 0.3 2.8e-12 46.3 0.1 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXS97304.1 - 0.036 14.2 0.0 0.26 11.4 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif AA_permease PF00324.21 KXS97305.1 - 5.8e-09 35.1 13.1 9.5e-08 31.1 5.8 2.0 1 1 1 2 2 2 2 Amino acid permease Tyrosinase PF00264.20 KXS97306.1 - 2.3e-51 175.2 0.3 3e-51 174.8 0.3 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Peptidase_M16 PF00675.20 KXS97307.1 - 9.1e-58 194.5 0.2 3.3e-57 192.6 0.3 1.9 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KXS97307.1 - 4.5e-38 131.1 0.0 1.4e-37 129.5 0.0 1.8 2 0 0 2 2 2 1 Peptidase M16 inactive domain WSC PF01822.19 KXS97308.1 - 3.9e-15 55.8 5.3 8.6e-15 54.7 5.3 1.6 1 0 0 1 1 1 1 WSC domain Abhydrolase_6 PF12697.7 KXS97308.1 - 0.0016 19.1 0.1 0.0042 17.7 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 KXS97308.1 - 0.014 15.1 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.20 KXS97308.1 - 0.12 12.4 0.2 0.81 9.8 0.2 2.0 1 1 0 2 2 2 0 Thioesterase domain Hydrolase_4 PF12146.8 KXS97308.1 - 0.12 11.6 0.0 0.34 10.1 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Ino80_Iec3 PF14612.6 KXS97312.1 - 4.4e-66 223.9 0.5 5.8e-66 223.5 0.5 1.1 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling HALZ PF02183.18 KXS97312.1 - 0.008 16.4 0.8 0.024 14.8 0.2 2.2 2 0 0 2 2 2 1 Homeobox associated leucine zipper CBM_14 PF01607.24 KXS97315.1 - 9.6e-11 41.7 7.3 9.6e-11 41.7 7.3 1.6 2 0 0 2 2 2 1 Chitin binding Peritrophin-A domain cNMP_binding PF00027.29 KXS97316.1 - 1.3e-32 111.7 0.0 1.3e-19 70.1 0.0 2.9 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain cNMPbd_u2 PF16643.5 KXS97316.1 - 1.8e-25 90.3 4.3 5.4e-25 88.7 4.3 1.8 1 0 0 1 1 1 1 Unstructured region on cNMP-binding protein LRR_6 PF13516.6 KXS97316.1 - 1.4e-09 37.3 1.2 1.4 9.1 0.0 7.4 8 0 0 8 8 8 3 Leucine Rich repeat F-box PF00646.33 KXS97316.1 - 1e-06 28.4 1.2 5.8e-06 26.0 0.1 2.8 3 0 0 3 3 3 1 F-box domain LRR_4 PF12799.7 KXS97316.1 - 6.5e-06 26.4 0.3 0.56 10.7 0.0 5.5 6 1 1 7 7 7 1 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KXS97316.1 - 1.1e-05 25.2 0.0 3.6e-05 23.6 0.0 2.0 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.33 KXS97316.1 - 5.6e-05 23.1 4.0 49 5.0 0.2 7.3 5 1 2 7 7 7 0 Leucine Rich Repeat CHZ PF09649.10 KXS97316.1 - 0.47 10.0 1.6 1.3 8.6 0.1 2.3 2 0 0 2 2 2 0 Histone chaperone domain CHZ Amidase PF01425.21 KXS97317.1 - 2.7e-33 115.6 0.6 4.4e-33 114.9 0.6 1.3 1 0 0 1 1 1 1 Amidase DUF3455 PF11937.8 KXS97319.1 - 8.9e-33 113.9 0.7 1.1e-32 113.5 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) MFS_MOT1 PF16983.5 KXS97320.1 - 1.4e-66 221.9 26.0 8.5e-34 116.3 8.7 2.5 2 0 0 2 2 2 2 Molybdate transporter of MFS superfamily Xan_ur_permease PF00860.20 KXS97320.1 - 4.6e-05 22.3 11.4 4.6e-05 22.3 11.4 2.8 1 1 1 3 3 3 2 Permease family TFR_dimer PF04253.15 KXS97321.1 - 4.3e-24 84.9 0.0 7.6e-24 84.1 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KXS97321.1 - 2.4e-21 76.4 0.0 5.6e-21 75.1 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.22 KXS97321.1 - 4.4e-08 33.0 0.9 2.3e-07 30.7 0.2 2.4 2 0 0 2 2 2 1 PA domain DUF2502 PF10697.9 KXS97321.1 - 0.12 12.7 1.3 0.28 11.5 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2502) MFS_1 PF07690.16 KXS97322.1 - 7.7e-42 143.5 26.2 2.3e-41 141.9 22.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS97322.1 - 1.6e-14 53.7 6.4 1.6e-14 53.7 6.4 2.0 1 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KXS97322.1 - 1.1e-09 37.4 5.8 1.7e-09 36.6 5.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 KXS97322.1 - 2.1e-05 24.0 4.3 2.1e-05 24.0 4.3 1.8 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 KXS97322.1 - 0.0074 15.2 1.7 0.013 14.4 1.5 1.5 1 1 0 1 1 1 1 MFS_1 like family MFS_3 PF05977.13 KXS97322.1 - 0.1 10.9 10.1 0.27 9.6 6.9 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector HAMP PF00672.25 KXS97323.1 - 1.4e-37 127.8 21.0 1.2e-08 35.2 0.3 7.5 6 1 1 7 7 7 6 HAMP domain HATPase_c PF02518.26 KXS97323.1 - 1.5e-28 99.5 1.3 5.2e-28 97.8 0.4 2.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXS97323.1 - 7e-27 93.8 0.5 7.2e-26 90.6 0.6 2.7 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 KXS97323.1 - 6.7e-16 58.1 0.4 6.7e-16 58.1 0.4 3.8 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain DUF3829 PF12889.7 KXS97323.1 - 0.0013 18.3 21.0 0.016 14.7 2.5 4.9 4 2 2 6 6 6 2 Protein of unknown function (DUF3829) DUF4279 PF14106.6 KXS97323.1 - 0.007 16.6 0.2 7.9 6.7 0.0 4.7 5 0 0 5 5 5 1 Domain of unknown function (DUF4279) IL32 PF15225.6 KXS97323.1 - 0.068 13.5 0.0 64 4.0 0.0 4.8 5 1 1 6 6 5 0 Interleukin 32 SpoIIID PF12116.8 KXS97323.1 - 0.098 12.8 3.6 25 5.0 0.1 4.4 4 0 0 4 4 3 0 Stage III sporulation protein D NAAA-beta PF15508.6 KXS97323.1 - 0.12 12.7 0.1 95 3.4 0.0 4.4 5 0 0 5 5 5 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF948 PF06103.11 KXS97323.1 - 0.23 11.7 55.3 0.67 10.3 1.0 9.9 5 4 1 7 7 7 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 KXS97323.1 - 1.9 8.7 39.3 0.25 11.5 3.1 7.1 6 1 1 7 7 7 0 Fibrinogen alpha/beta chain family DUF5593 PF18007.1 KXS97323.1 - 3.2 8.5 5.1 82 4.0 0.1 4.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5593) AcylCoA_dehyd_C PF12186.8 KXS97323.1 - 6.1 7.0 12.0 36 4.5 0.4 6.1 6 1 1 7 7 7 0 Acyl-CoA dehydrogenase C terminal EDR1 PF14381.6 KXS97323.1 - 6.7 6.4 15.4 1.9 8.2 0.2 5.1 1 1 2 5 5 5 0 Ethylene-responsive protein kinase Le-CTR1 Sugar_tr PF00083.24 KXS97327.1 - 1.5e-89 301.0 17.0 1.9e-89 300.6 17.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS97327.1 - 2.4e-12 46.5 40.4 1.6e-09 37.2 26.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_S10 PF00450.22 KXS97328.1 - 9.7e-66 222.9 4.7 1.3e-65 222.5 4.7 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Melibiase_2 PF16499.5 KXS97328.1 - 0.035 13.3 0.1 0.12 11.5 0.0 1.8 2 0 0 2 2 2 0 Alpha galactosidase A Peptidase_S10 PF00450.22 KXS97329.1 - 9.7e-66 222.9 4.7 1.3e-65 222.5 4.7 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Melibiase_2 PF16499.5 KXS97329.1 - 0.035 13.3 0.1 0.12 11.5 0.0 1.8 2 0 0 2 2 2 0 Alpha galactosidase A A_deaminase PF00962.22 KXS97330.1 - 3.5e-19 69.3 0.0 1.7e-18 67.1 0.0 2.0 1 1 0 1 1 1 1 Adenosine/AMP deaminase NOA36 PF06524.12 KXS97332.1 - 3.8 6.8 7.7 4.6 6.5 7.7 1.1 1 0 0 1 1 1 0 NOA36 protein HMG_box PF00505.19 KXS97334.1 - 2.8e-14 53.3 0.6 8.5e-14 51.7 0.6 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KXS97334.1 - 5.1e-06 27.0 0.3 1.5e-05 25.5 0.3 1.9 1 0 0 1 1 1 1 HMG-box domain CDC45 PF02724.14 KXS97334.1 - 0.26 9.5 10.9 0.4 8.9 10.9 1.3 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.12 KXS97334.1 - 2.6 7.7 15.5 0.11 12.3 6.0 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Macoilin PF09726.9 KXS97334.1 - 3.3 6.2 4.6 4.6 5.7 4.6 1.2 1 0 0 1 1 1 0 Macoilin family Plasmodium_Vir PF05795.11 KXS97334.1 - 7.7 5.8 8.2 0.21 11.0 1.5 1.7 2 0 0 2 2 2 0 Plasmodium vivax Vir protein DNA_pol_phi PF04931.13 KXS97334.1 - 7.8 4.5 17.2 12 3.8 17.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi Lin-8 PF03353.15 KXS97334.1 - 8.6 5.8 11.2 14 5.1 11.2 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist HMG_box PF00505.19 KXS97337.1 - 2.2e-14 53.6 0.6 7.8e-14 51.8 0.6 2.0 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KXS97337.1 - 4.2e-06 27.3 0.3 1.4e-05 25.6 0.3 2.0 1 0 0 1 1 1 1 HMG-box domain Lin-8 PF03353.15 KXS97337.1 - 5.6 6.4 10.9 9.4 5.7 10.9 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DNA_pol_phi PF04931.13 KXS97337.1 - 6.7 4.7 17.2 11 3.9 17.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi UDPGP PF01704.18 KXS97338.1 - 2e-59 201.3 0.0 2.7e-59 200.9 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Fer4_20 PF14691.6 KXS97338.1 - 0.13 12.0 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster p450 PF00067.22 KXS97339.1 - 7.4e-06 25.0 0.0 0.0019 17.0 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 rpo30_N PF12410.8 KXS97339.1 - 0.026 14.4 0.1 0.073 13.0 0.0 1.7 1 1 0 1 1 1 0 Poxvirus DNA dependent RNA polymerase 30kDa subunit ATG2_CAD PF13329.6 KXS97340.1 - 1.4e-39 135.3 0.1 2.7e-39 134.4 0.1 1.5 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.11 KXS97340.1 - 1.3e-27 95.9 0.0 3.5e-27 94.6 0.0 1.8 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain DEAD PF00270.29 KXS97341.1 - 3.2e-47 160.6 0.1 9e-47 159.1 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXS97341.1 - 1.7e-23 83.0 0.0 2.9e-22 79.1 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KXS97341.1 - 1e-19 70.5 0.1 1.9e-19 69.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) MAJIN PF15077.6 KXS97341.1 - 0.75 9.5 14.7 1.4 8.6 14.7 1.5 1 0 0 1 1 1 0 Membrane-anchored junction protein CDC27 PF09507.10 KXS97341.1 - 7.4 5.8 36.5 12 5.1 36.5 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DEAD PF00270.29 KXS97342.1 - 3.2e-47 160.5 0.1 9.1e-47 159.1 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXS97342.1 - 1.8e-23 83.0 0.0 2.9e-22 79.1 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KXS97342.1 - 1e-19 70.5 0.1 1.9e-19 69.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) MAJIN PF15077.6 KXS97342.1 - 0.76 9.5 14.7 1.4 8.6 14.7 1.5 1 0 0 1 1 1 0 Membrane-anchored junction protein CDC27 PF09507.10 KXS97342.1 - 7.5 5.8 36.5 12 5.1 36.5 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF373 PF04123.13 KXS97343.1 - 1.3 8.4 3.4 1.6 8.1 3.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Glyco_transf_28 PF03033.20 KXS97345.1 - 1.5e-17 63.9 0.2 7.3e-17 61.7 0.0 2.2 2 1 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KXS97345.1 - 2.7e-08 33.0 0.0 4.6e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KXS97345.1 - 0.00022 21.3 0.0 0.00059 19.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain adh_short PF00106.25 KXS97346.1 - 5.5e-29 101.0 0.1 7e-29 100.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS97346.1 - 5.1e-25 88.4 0.0 6.7e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS97346.1 - 1.2e-08 35.1 0.1 7.4e-08 32.5 0.1 2.0 2 0 0 2 2 2 1 KR domain TPMT PF05724.11 KXS97347.1 - 1.1e-31 110.2 0.0 3.2e-31 108.7 0.0 1.6 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.6 KXS97347.1 - 1.4e-07 31.5 0.0 2.3e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS97347.1 - 9.1e-07 29.5 0.1 4e-06 27.4 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS97347.1 - 1.9e-06 28.4 0.0 6.1e-06 26.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS97347.1 - 2.1e-06 27.6 0.2 2.1e-05 24.3 0.2 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS97347.1 - 8e-06 26.5 0.0 4e-05 24.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KXS97347.1 - 0.00016 21.2 0.0 0.0015 18.0 0.0 2.0 2 0 0 2 2 2 1 Tellurite resistance protein TehB AdoMet_MTase PF07757.13 KXS97347.1 - 0.2 12.0 0.1 0.45 10.9 0.1 1.6 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase zinc_ribbon_15 PF17032.5 KXS97348.1 - 0.00016 22.4 2.3 0.00023 21.8 2.3 1.3 1 0 0 1 1 1 1 zinc-ribbon family Rad51 PF08423.11 KXS97349.1 - 6.6e-95 317.2 1.6 2.9e-71 239.7 0.0 2.4 2 1 1 3 3 3 2 Rad51 ATPase PF06745.13 KXS97349.1 - 1.8e-06 27.5 0.1 0.0083 15.5 0.0 2.9 3 0 0 3 3 3 2 KaiC RecA PF00154.21 KXS97349.1 - 0.00022 20.8 0.0 0.088 12.3 0.0 2.1 2 0 0 2 2 2 2 recA bacterial DNA recombination protein HHH_5 PF14520.6 KXS97349.1 - 0.00047 20.7 0.0 0.002 18.7 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain zf-CCHC PF00098.23 KXS97350.1 - 2.8e-46 153.6 62.0 4.1e-08 33.0 2.3 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 KXS97350.1 - 1.5e-09 37.4 45.2 0.061 13.1 1.0 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_5 PF14787.6 KXS97350.1 - 9.7e-07 28.4 41.6 0.018 14.7 0.9 7.0 4 2 3 7 7 7 5 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 KXS97350.1 - 4.5e-05 23.3 44.1 0.025 14.6 0.2 6.9 4 2 2 6 6 6 4 Zinc knuckle Rad51 PF08423.11 KXS97351.1 - 6.6e-95 317.2 1.6 2.9e-71 239.7 0.0 2.4 2 1 1 3 3 3 2 Rad51 ATPase PF06745.13 KXS97351.1 - 1.8e-06 27.5 0.1 0.0083 15.5 0.0 2.9 3 0 0 3 3 3 2 KaiC RecA PF00154.21 KXS97351.1 - 0.00022 20.8 0.0 0.088 12.3 0.0 2.1 2 0 0 2 2 2 2 recA bacterial DNA recombination protein HHH_5 PF14520.6 KXS97351.1 - 0.00047 20.7 0.0 0.002 18.7 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain zf-CCHC PF00098.23 KXS97352.1 - 2.8e-46 153.6 62.0 4.1e-08 33.0 2.3 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 KXS97352.1 - 1.5e-09 37.4 45.2 0.061 13.1 1.0 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_5 PF14787.6 KXS97352.1 - 9.7e-07 28.4 41.6 0.018 14.7 0.9 7.0 4 2 3 7 7 7 5 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 KXS97352.1 - 4.5e-05 23.3 44.1 0.025 14.6 0.2 6.9 4 2 2 6 6 6 4 Zinc knuckle CybS PF05328.12 KXS97353.1 - 1e-44 151.5 0.0 1.4e-44 151.0 0.0 1.2 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Thia_YuaJ PF09515.10 KXS97353.1 - 0.38 10.8 2.7 0.17 11.9 0.6 1.5 2 0 0 2 2 2 0 Thiamine transporter protein (Thia_YuaJ) SNF2_N PF00176.23 KXS97354.1 - 4.3e-75 252.6 0.0 8.3e-75 251.7 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 KXS97354.1 - 2.2e-42 143.7 1.6 2.2e-42 143.7 1.6 2.8 2 0 0 2 2 2 1 SLIDE HAND PF09110.11 KXS97354.1 - 1.3e-35 122.5 2.4 1.3e-35 122.5 2.4 3.1 4 0 0 4 4 2 1 HAND Helicase_C PF00271.31 KXS97354.1 - 6.1e-19 68.4 0.2 5.7e-18 65.3 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXS97354.1 - 3.8e-11 43.3 0.1 2.1e-10 40.9 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Myb_DNA-binding PF00249.31 KXS97354.1 - 2.2e-06 27.7 0.0 0.0088 16.2 0.0 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain HDA2-3 PF11496.8 KXS97354.1 - 2.2e-05 23.8 0.1 0.00016 21.0 0.0 2.4 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 KXS97354.1 - 0.00012 21.9 0.0 0.00029 20.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KXS97354.1 - 0.00048 19.9 0.1 0.0015 18.3 0.0 1.9 2 0 0 2 2 2 1 SWI2/SNF2 ATPase DEAD_2 PF06733.15 KXS97354.1 - 0.025 14.2 0.1 0.055 13.1 0.1 1.5 1 0 0 1 1 1 0 DEAD_2 AAA_14 PF13173.6 KXS97354.1 - 0.055 13.5 0.1 0.17 11.9 0.1 1.9 1 0 0 1 1 1 0 AAA domain DUF4611 PF15387.6 KXS97354.1 - 0.1 12.9 0.2 0.1 12.9 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) AAA_22 PF13401.6 KXS97354.1 - 1.3 9.3 5.2 0.89 9.8 0.1 3.2 4 0 0 4 4 4 0 AAA domain MFS_1 PF07690.16 KXS97355.1 - 8e-41 140.1 38.6 8e-41 140.1 38.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Oxysterol_BP PF01237.18 KXS97358.1 - 1.8e-58 198.2 0.0 3.2e-51 174.3 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein zf-CCHC PF00098.23 KXS97359.1 - 0.0022 18.0 43.8 0.0048 16.9 4.1 5.7 5 1 0 5 5 5 4 Zinc knuckle Apt1 PF10351.9 KXS97359.1 - 0.13 11.1 5.5 0.13 11.1 5.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain GEN1_C PF18380.1 KXS97359.1 - 1.1 10.2 5.3 0.95 10.4 0.5 2.5 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain Sulfotransfer_4 PF17784.1 KXS97360.1 - 6.6e-70 235.3 0.1 1e-69 234.7 0.1 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Arylsulfotran_2 PF14269.6 KXS97360.1 - 1.2e-53 182.4 3.5 2.2e-53 181.6 3.5 1.4 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KXS97360.1 - 7.5e-19 67.9 4.8 1.5e-17 63.6 4.8 2.6 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Sulfotransfer_3 PF13469.6 KXS97360.1 - 8.6e-05 23.0 0.1 0.0062 16.9 0.0 2.4 1 1 1 2 2 2 1 Sulfotransferase family Na_H_Exchanger PF00999.21 KXS97362.1 - 1.7e-27 96.2 30.9 2.8e-23 82.3 19.9 3.1 3 0 0 3 3 3 3 Sodium/hydrogen exchanger family PIG-H PF10181.9 KXS97363.1 - 9.8e-24 83.0 0.1 1.5e-23 82.5 0.1 1.3 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Na_H_Exchanger PF00999.21 KXS97364.1 - 1.7e-27 96.2 30.9 2.8e-23 82.3 19.9 3.1 3 0 0 3 3 3 3 Sodium/hydrogen exchanger family NDUFA12 PF05071.16 KXS97365.1 - 7.7e-13 49.1 1.4 7.7e-13 49.1 1.4 1.9 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Pkinase PF00069.25 KXS97366.1 - 1.9e-20 73.4 0.0 1.5e-17 63.8 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXS97366.1 - 3.8e-09 36.2 0.0 1.7e-08 34.1 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXS97366.1 - 0.0066 16.4 0.1 0.021 14.7 0.1 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Transthyretin PF00576.21 KXS97367.1 - 3.7e-34 117.7 0.0 6.4e-34 117.0 0.0 1.4 1 0 0 1 1 1 1 HIUase/Transthyretin family Pkinase PF00069.25 KXS97367.1 - 1.3e-18 67.4 0.0 3.2e-18 66.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS97367.1 - 2.1e-07 30.5 0.0 3.7e-06 26.4 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase HECT PF00632.25 KXS97368.1 - 5.4e-73 246.2 0.0 7.2e-73 245.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Amidohydro_1 PF01979.20 KXS97369.1 - 2.5e-25 89.5 0.0 3.7e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXS97369.1 - 3.4e-21 76.3 0.1 2e-10 40.8 0.0 3.1 2 1 1 3 3 3 3 Amidohydrolase family AhpC-TSA PF00578.21 KXS97370.1 - 1.2e-32 112.4 0.1 1.7e-32 112.0 0.1 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KXS97370.1 - 4.9e-17 62.0 0.0 6.3e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KXS97370.1 - 2.3e-11 43.3 0.3 4.3e-11 42.5 0.3 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA_2 PF13911.6 KXS97370.1 - 0.054 13.6 0.0 0.11 12.6 0.0 1.5 1 1 0 1 1 1 0 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 KXS97371.1 - 1.2e-32 112.4 0.1 1.7e-32 112.0 0.1 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KXS97371.1 - 4.9e-17 62.0 0.0 6.3e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KXS97371.1 - 2.3e-11 43.3 0.3 4.3e-11 42.5 0.3 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA_2 PF13911.6 KXS97371.1 - 0.054 13.6 0.0 0.11 12.6 0.0 1.5 1 1 0 1 1 1 0 AhpC/TSA antioxidant enzyme Ribosomal_L15e PF00827.17 KXS97372.1 - 3e-90 301.1 11.1 3.8e-90 300.7 11.1 1.1 1 0 0 1 1 1 1 Ribosomal L15 Ribosomal_L15e PF00827.17 KXS97373.1 - 2.7e-78 262.1 9.8 3.8e-78 261.6 9.8 1.1 1 0 0 1 1 1 1 Ribosomal L15 PseudoU_synth_1 PF01416.20 KXS97374.1 - 4.1e-35 120.5 0.0 2e-33 115.1 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase MFS_1 PF07690.16 KXS97375.1 - 0.0002 20.4 37.2 0.0036 16.3 25.1 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF4381 PF14316.6 KXS97375.1 - 7 6.9 6.9 31 4.8 0.0 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4381) ArsA_ATPase PF02374.15 KXS97377.1 - 1.2e-106 356.4 0.0 1.4e-106 356.2 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 KXS97377.1 - 4.1e-14 52.9 0.4 4.1e-13 49.6 0.0 2.5 2 2 0 2 2 2 1 AAA domain CbiA PF01656.23 KXS97377.1 - 5.1e-12 46.0 0.0 6.9e-12 45.5 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 KXS97377.1 - 3.5e-06 26.7 0.1 7.4e-06 25.6 0.1 1.5 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 KXS97377.1 - 1.5e-05 24.7 0.1 0.0008 19.1 0.2 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain ParA PF10609.9 KXS97377.1 - 1.9e-05 24.2 1.2 0.00013 21.6 0.3 2.5 3 0 0 3 3 3 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 KXS97377.1 - 0.00017 21.1 0.0 0.00091 18.8 0.0 2.0 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ AAA_25 PF13481.6 KXS97377.1 - 0.0019 17.8 0.1 0.025 14.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KXS97377.1 - 0.01 15.2 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin PhoH PF02562.16 KXS97377.1 - 0.035 13.6 0.0 0.073 12.5 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein NB-ARC PF00931.22 KXS97377.1 - 0.14 11.3 0.1 0.3 10.2 0.1 1.5 1 0 0 1 1 1 0 NB-ARC domain ORMDL PF04061.14 KXS97378.1 - 2.1e-57 192.7 5.3 2.4e-57 192.5 5.3 1.0 1 0 0 1 1 1 1 ORMDL family DUF2208 PF09973.9 KXS97378.1 - 0.071 12.7 0.0 0.071 12.7 0.0 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) RsmJ PF04378.13 KXS97378.1 - 0.17 11.1 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA large subunit methyltransferase D, RlmJ Hydrolase PF00702.26 KXS97379.1 - 1.7e-10 41.5 0.0 1.3e-06 28.9 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KXS97379.1 - 2.2e-09 37.6 0.0 4.5e-08 33.4 0.0 2.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXS97379.1 - 1.2e-06 28.5 0.0 2.2e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 KXS97379.1 - 0.014 15.8 0.0 0.045 14.1 0.0 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Gam PF06064.11 KXS97379.1 - 0.04 14.1 0.0 0.065 13.5 0.0 1.4 1 0 0 1 1 1 0 Host-nuclease inhibitor protein Gam Fis1_TPR_N PF14852.6 KXS97379.1 - 0.56 9.9 2.3 0.68 9.7 0.1 2.4 3 0 0 3 3 3 0 Fis1 N-terminal tetratricopeptide repeat PP-binding PF00550.25 KXS97381.1 - 9.3e-15 54.7 5.9 1.3e-07 31.8 0.2 2.9 3 0 0 3 3 3 2 Phosphopantetheine attachment site RXT2_N PF08595.11 KXS97382.1 - 0.018 15.1 0.6 0.026 14.6 0.6 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal SNF2_N PF00176.23 KXS97382.1 - 0.046 12.4 0.0 0.089 11.5 0.0 1.4 1 1 0 1 1 1 0 SNF2 family N-terminal domain DNA_pol_phi PF04931.13 KXS97382.1 - 0.052 11.7 1.9 0.062 11.4 1.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF688 PF05097.12 KXS97382.1 - 0.099 11.8 2.4 0.13 11.4 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF688) DUF3073 PF11273.8 KXS97382.1 - 0.26 12.0 3.8 18 6.1 2.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3073) CN_hydrolase PF00795.22 KXS97383.1 - 1.2e-56 192.0 0.0 1.5e-56 191.6 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Rieske_3 PF18465.1 KXS97383.1 - 0.017 15.4 0.0 0.045 14.0 0.0 1.6 1 0 0 1 1 1 0 Rieske 3Fe-4S Arylsulfotran_2 PF14269.6 KXS97385.1 - 8e-42 143.6 0.0 2.6e-41 142.0 0.0 1.8 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KXS97385.1 - 1.6e-08 33.9 0.0 3.1e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) CN_hydrolase PF00795.22 KXS97386.1 - 1.3e-43 149.3 0.0 1.7e-43 148.9 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase AMP-binding PF00501.28 KXS97387.1 - 9.8e-57 192.4 0.0 1.7e-56 191.6 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 KXS97387.1 - 2.7e-14 53.2 0.0 6e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep PF00132.24 KXS97387.1 - 7.6e-11 41.3 3.2 0.002 17.8 0.0 5.9 5 1 1 6 6 5 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KXS97387.1 - 0.21 11.4 10.8 4.8 7.0 0.3 5.3 6 0 0 6 6 6 0 Hexapeptide repeat of succinyl-transferase TRI12 PF06609.13 KXS97388.1 - 3.8e-53 180.9 20.2 4.5e-53 180.6 20.2 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KXS97388.1 - 8.5e-13 47.9 47.4 2.3e-10 39.9 42.9 3.1 2 1 0 2 2 2 2 Major Facilitator Superfamily Phage_holin_3_6 PF07332.11 KXS97388.1 - 0.037 14.0 0.3 0.037 14.0 0.3 5.1 4 1 1 5 5 5 0 Putative Actinobacterial Holin-X, holin superfamily III Glyco_transf_90 PF05686.12 KXS97389.1 - 3.5e-20 72.3 1.2 3.5e-20 72.3 1.2 1.5 2 0 0 2 2 2 1 Glycosyl transferase family 90 DUF378 PF04070.12 KXS97389.1 - 0.015 15.2 0.7 0.024 14.5 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF378) Fungal_trans_2 PF11951.8 KXS97390.1 - 3.5e-09 36.0 3.2 9e-09 34.6 3.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS97390.1 - 4e-07 30.1 10.3 8.2e-07 29.0 10.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MCM_OB PF17207.3 KXS97390.1 - 0.94 9.3 3.1 2.3 8.1 3.1 1.6 1 0 0 1 1 1 0 MCM OB domain TALPID3 PF15324.6 KXS97390.1 - 1.4 6.5 7.4 1.9 6.0 7.4 1.1 1 0 0 1 1 1 0 Hedgehog signalling target Esterase_phd PF10503.9 KXS97391.1 - 0.00046 19.8 0.0 0.00076 19.0 0.0 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KXS97391.1 - 0.0015 18.0 0.6 0.0056 16.2 0.6 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KXS97391.1 - 0.042 13.6 0.0 0.063 13.1 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF1033 PF06279.11 KXS97394.1 - 0.12 12.6 0.8 5.5 7.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1033) BUD22 PF09073.10 KXS97395.1 - 0.00029 20.3 16.3 0.00034 20.1 16.3 1.0 1 0 0 1 1 1 1 BUD22 CDC27 PF09507.10 KXS97395.1 - 0.011 15.1 13.0 0.012 15.0 13.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CCDC71L PF15374.6 KXS97395.1 - 0.39 9.9 13.1 0.5 9.6 13.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L Dicty_REP PF05086.12 KXS97395.1 - 0.9 7.4 4.6 1.1 7.1 4.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PPP4R2 PF09184.11 KXS97395.1 - 4 6.9 11.6 5.5 6.5 11.6 1.2 1 0 0 1 1 1 0 PPP4R2 Hid1 PF12722.7 KXS97396.1 - 0.013 13.7 17.5 0.014 13.6 17.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein LAP1C PF05609.12 KXS97396.1 - 9.8 5.1 29.9 16 4.4 29.9 1.5 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) PBP_sp32 PF07222.12 KXS97397.1 - 2.3 7.6 10.4 4.8 6.6 10.4 1.5 1 0 0 1 1 1 0 Proacrosin binding protein sp32 PGA2 PF07543.12 KXS97397.1 - 3.4 7.6 20.4 0.22 11.5 3.6 3.4 3 0 0 3 3 3 0 Protein trafficking PGA2 SAP PF02037.27 KXS97398.1 - 0.00023 20.8 0.0 0.00039 20.1 0.0 1.4 1 0 0 1 1 1 1 SAP domain ProSAAS PF07259.12 KXS97398.1 - 0.016 15.1 0.2 0.021 14.8 0.2 1.2 1 0 0 1 1 1 0 ProSAAS precursor DUF4017 PF13209.6 KXS97398.1 - 0.062 13.2 0.3 0.11 12.4 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4017) Trypan_PARP PF05887.11 KXS97399.1 - 0.00019 21.4 38.2 0.00024 21.1 37.7 1.5 1 1 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) CDC45 PF02724.14 KXS97399.1 - 0.025 12.9 7.6 0.033 12.5 7.6 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 KXS97399.1 - 0.43 10.4 7.4 0.55 10.0 7.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PTPRCAP PF15713.5 KXS97399.1 - 1.3 9.3 9.6 2.5 8.4 9.6 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Merozoite_SPAM PF07133.11 KXS97399.1 - 7.4 6.5 16.5 11 6.0 16.5 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Pkinase PF00069.25 KXS97406.1 - 1.6e-41 142.4 0.0 2.5e-41 141.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS97406.1 - 8.6e-25 87.5 0.0 1.2e-24 87.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KXS97406.1 - 1.5e-07 31.7 0.0 3.7e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 KXS97406.1 - 7e-05 22.3 0.0 0.00031 20.1 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Yop-YscD_cpl PF16697.5 KXS97406.1 - 0.001 19.4 0.0 0.0023 18.2 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain APH PF01636.23 KXS97406.1 - 0.033 14.1 0.4 0.11 12.4 0.3 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXS97406.1 - 0.12 11.1 1.5 0.17 10.6 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase DUF1697 PF08002.11 KXS97407.1 - 0.034 14.6 0.0 0.068 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1697) ECH_1 PF00378.20 KXS97408.1 - 0.036 13.4 0.2 0.05 12.9 0.2 1.2 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase DEAD PF00270.29 KXS97415.1 - 4.3e-47 160.2 0.0 8.9e-47 159.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXS97415.1 - 2.1e-23 82.8 0.0 1.3e-22 80.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KXS97415.1 - 4.6e-17 62.0 0.1 1.3e-16 60.5 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Sugar_tr PF00083.24 KXS97416.1 - 2.9e-89 300.0 28.7 3.6e-89 299.7 28.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS97416.1 - 5.7e-24 84.7 38.0 3.4e-23 82.2 30.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily RuBisCO_large_N PF02788.16 KXS97416.1 - 0.00063 19.9 0.1 0.0015 18.7 0.0 1.6 2 0 0 2 2 2 1 Ribulose bisphosphate carboxylase large chain, N-terminal domain Phage_holin_3_2 PF04550.12 KXS97416.1 - 0.024 15.2 3.3 0.024 15.2 3.3 2.5 3 0 0 3 3 3 0 Phage holin family 2 ECH_1 PF00378.20 KXS97417.1 - 5.4e-49 166.8 0.2 3.2e-48 164.2 0.2 1.8 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXS97417.1 - 3.1e-23 82.8 2.0 2.1e-20 73.5 0.7 2.5 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KXS97417.1 - 0.00082 19.4 0.3 0.015 15.3 0.0 2.1 1 1 0 2 2 2 1 Peptidase family S49 Transp_cyt_pur PF02133.15 KXS97421.1 - 1.7e-34 119.4 33.2 2.8e-34 118.7 33.2 1.3 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin NDUF_B12 PF08122.12 KXS97421.1 - 0.25 11.4 1.4 0.58 10.3 0.3 2.3 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family Transp_cyt_pur PF02133.15 KXS97422.1 - 1.7e-34 119.4 33.2 2.8e-34 118.7 33.2 1.3 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin NDUF_B12 PF08122.12 KXS97422.1 - 0.25 11.4 1.4 0.58 10.3 0.3 2.3 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family Abhydrolase_3 PF07859.13 KXS97423.1 - 5e-58 196.4 0.0 6.6e-58 196.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXS97423.1 - 1.7e-10 40.4 0.1 3.9e-10 39.2 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KXS97423.1 - 1.9e-06 27.5 0.2 6.7e-05 22.5 0.1 2.6 2 1 0 2 2 2 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 KXS97423.1 - 1.4e-05 24.1 0.0 2.2e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Esterase PF00756.20 KXS97423.1 - 0.0024 17.5 0.0 0.18 11.4 0.0 2.5 3 0 0 3 3 3 1 Putative esterase Chlorophyllase2 PF12740.7 KXS97423.1 - 0.045 12.7 0.1 0.12 11.2 0.1 1.7 1 1 0 1 1 1 0 Chlorophyllase enzyme MOZ_SAS PF01853.18 KXS97424.1 - 2.8e-80 268.2 0.0 4.1e-80 267.6 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KXS97424.1 - 4.8e-24 83.7 0.3 9.2e-24 82.8 0.3 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 KXS97424.1 - 1.2e-22 79.5 0.0 2.4e-22 78.6 0.0 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 KXS97424.1 - 0.0043 17.4 0.0 0.0094 16.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Chromo PF00385.24 KXS97424.1 - 0.03 14.2 0.0 0.063 13.2 0.0 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Acetyltransf_1 PF00583.25 KXS97424.1 - 0.059 13.6 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family NIR_SIR PF01077.22 KXS97425.1 - 8.3e-54 181.4 0.0 1.4e-47 161.2 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 KXS97425.1 - 2e-32 110.9 0.0 1.5e-15 56.8 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 KXS97425.1 - 3.5e-30 105.1 0.0 7.7e-30 104.0 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.19 KXS97425.1 - 1.5e-09 38.0 0.4 7e-09 35.8 0.1 2.0 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg DHC_N1 PF08385.12 KXS97425.1 - 0.18 10.4 0.0 0.29 9.7 0.0 1.2 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 Cu-oxidase_3 PF07732.15 KXS97426.1 - 3.9e-38 130.1 0.3 1.5e-37 128.2 0.2 2.1 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KXS97426.1 - 5.4e-28 97.4 5.9 7.1e-26 90.6 0.2 3.5 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 KXS97426.1 - 9.2e-17 61.6 0.0 2.3e-15 57.1 0.0 3.1 3 1 0 3 3 3 1 Multicopper oxidase ATPgrasp_N PF18130.1 KXS97428.1 - 2.8e-13 50.2 0.0 5.8e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp N-terminal domain ATP-grasp_4 PF13535.6 KXS97428.1 - 1.2e-08 34.7 0.0 2.4e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Glyco_hydro_92 PF07971.12 KXS97429.1 - 2.2e-126 422.5 2.6 2.8e-126 422.2 2.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KXS97429.1 - 3e-42 145.2 1.7 5.1e-42 144.4 1.7 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain HTH_38 PF13936.6 KXS97429.1 - 1.3e-09 37.7 3.3 0.00038 20.1 0.1 3.8 4 0 0 4 4 4 2 Helix-turn-helix domain Myb_DNA-binding PF00249.31 KXS97429.1 - 3.6e-09 36.7 6.3 0.0023 18.1 0.0 5.0 5 0 0 5 5 5 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXS97429.1 - 6.1e-06 26.4 1.2 0.069 13.4 0.1 4.8 3 2 1 4 4 4 1 Myb-like DNA-binding domain HTH_23 PF13384.6 KXS97429.1 - 6.7e-05 22.6 3.5 0.0088 15.8 0.1 3.7 4 0 0 4 4 4 1 Homeodomain-like domain GcrA PF07750.11 KXS97429.1 - 0.00038 20.9 7.4 3.5 8.0 0.0 4.4 5 0 0 5 5 5 3 GcrA cell cycle regulator Sigma70_r4_2 PF08281.12 KXS97429.1 - 0.0079 15.9 0.1 1.1 9.0 0.1 3.3 3 0 0 3 3 3 1 Sigma-70, region 4 HTH_7 PF02796.15 KXS97429.1 - 0.011 15.8 0.0 7.3 6.8 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase RepB PF07506.11 KXS97429.1 - 0.081 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 RepB plasmid partitioning protein ABC_membrane PF00664.23 KXS97430.1 - 2.1e-87 293.3 31.2 2.2e-48 165.3 13.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXS97430.1 - 7.3e-70 233.8 0.0 4.3e-34 118.0 0.0 2.9 3 0 0 3 3 3 2 ABC transporter Abhydrolase_1 PF00561.20 KXS97430.1 - 2.3e-17 63.5 0.0 1.8e-16 60.6 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold SMC_N PF02463.19 KXS97430.1 - 3e-16 59.5 0.1 8.5e-05 22.1 0.0 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain Abhydrolase_4 PF08386.10 KXS97430.1 - 4e-13 49.4 0.0 9.2e-13 48.2 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein ABC_ATPase PF09818.9 KXS97430.1 - 1.8e-11 43.5 3.1 0.0015 17.4 0.2 3.7 4 1 0 4 4 4 3 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 KXS97430.1 - 7.1e-08 32.5 0.0 0.019 14.9 0.0 3.3 3 0 0 3 3 3 2 RsgA GTPase AAA_15 PF13175.6 KXS97430.1 - 1.2e-07 31.8 0.0 0.0007 19.4 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 KXS97430.1 - 2e-07 30.5 0.0 0.00022 20.6 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_29 PF13555.6 KXS97430.1 - 3.6e-07 29.8 0.4 0.0044 16.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 KXS97430.1 - 8.4e-07 29.1 0.6 0.0073 16.2 0.0 3.8 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KXS97430.1 - 6.1e-06 26.6 1.7 0.03 14.6 0.0 3.3 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KXS97430.1 - 9e-05 22.9 5.8 0.23 11.9 0.7 3.4 2 2 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 KXS97430.1 - 0.00023 21.0 0.5 1.1 8.9 0.0 3.3 3 1 0 3 3 3 2 AAA domain AAA_33 PF13671.6 KXS97430.1 - 0.00045 20.4 0.0 1.7 8.8 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KXS97430.1 - 0.00057 19.5 1.9 0.39 10.3 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.6 KXS97430.1 - 0.0054 17.3 0.0 5.2 7.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KXS97430.1 - 0.006 17.1 3.0 0.33 11.4 0.3 2.9 2 1 1 3 3 3 1 AAA domain SbcCD_C PF13558.6 KXS97430.1 - 0.0074 16.5 6.2 0.85 9.9 0.3 4.0 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit G-alpha PF00503.20 KXS97430.1 - 0.01 15.1 0.0 1.9 7.6 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit APS_kinase PF01583.20 KXS97430.1 - 0.012 15.6 0.1 2.5 8.0 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase MMR_HSR1 PF01926.23 KXS97430.1 - 0.049 13.7 0.1 4.3 7.4 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF87 PF01935.17 KXS97430.1 - 0.072 13.2 0.2 0.62 10.1 0.0 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_28 PF13521.6 KXS97430.1 - 0.15 12.3 1.8 1.3 9.3 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KXS97430.1 - 0.15 12.1 0.3 30 4.6 0.0 3.0 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Glyco_hydro_43 PF04616.14 KXS97431.1 - 1.2e-62 211.8 13.5 2e-52 178.3 5.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 KXS97431.1 - 7e-10 39.0 4.8 8.1e-06 25.6 0.2 2.4 2 0 0 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain DnaJ PF00226.31 KXS97432.1 - 3.8e-16 59.0 1.1 3.8e-16 59.0 1.1 2.3 3 0 0 3 3 3 1 DnaJ domain SAP130_C PF16014.5 KXS97433.1 - 0.58 9.2 11.4 1.1 8.3 11.4 1.4 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus FMO-like PF00743.19 KXS97434.1 - 1.6e-49 168.8 0.0 1.9e-49 168.5 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXS97434.1 - 8.5e-22 77.8 0.0 1.8e-20 73.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXS97434.1 - 7e-09 35.3 0.0 2.3e-08 33.7 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXS97434.1 - 1.5e-05 25.1 0.0 4.1e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KXS97434.1 - 2.2e-05 23.8 0.0 7.5e-05 22.0 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KXS97434.1 - 0.00051 20.6 0.0 1.8 9.2 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXS97434.1 - 0.003 17.5 0.0 0.17 11.9 0.0 3.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 KXS97434.1 - 0.0049 16.5 0.0 2.6 7.5 0.0 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.14 KXS97434.1 - 0.0093 14.7 0.0 0.015 14.0 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 KXS97434.1 - 0.02 14.2 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Amino_oxidase PF01593.24 KXS97434.1 - 0.14 11.4 0.0 0.69 9.1 0.0 1.9 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 KXS97434.1 - 0.26 10.6 0.0 0.4 10.0 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase RNase_T PF00929.24 KXS97435.1 - 6.2e-11 43.1 0.0 1.1e-10 42.4 0.0 1.4 1 0 0 1 1 1 1 Exonuclease Met_10 PF02475.16 KXS97436.1 - 1.2e-07 31.7 0.0 3.5e-07 30.2 0.0 1.6 1 1 0 1 1 1 1 Met-10+ like-protein LapA_dom PF06305.11 KXS97442.1 - 0.073 12.9 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain FAM176 PF14851.6 KXS97442.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 FAM176 family tRNA-synt_1c PF00749.21 KXS97443.1 - 5.7e-87 291.5 0.0 8.7e-87 290.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain MFS_1 PF07690.16 KXS97444.1 - 1.4e-12 47.3 0.3 2.6e-11 43.1 0.3 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3180 PF11377.8 KXS97444.1 - 0.032 14.4 0.1 0.1 12.7 0.0 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3180) TctB PF07331.11 KXS97444.1 - 0.06 13.6 0.2 5.5 7.3 0.0 2.2 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family Sugar_tr PF00083.24 KXS97445.1 - 3.7e-112 375.5 23.3 4.4e-112 375.2 23.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS97445.1 - 5.4e-29 101.2 34.3 1.8e-28 99.5 24.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_5 PF05631.14 KXS97445.1 - 0.00036 19.6 0.8 0.00078 18.5 0.8 1.5 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM Phage_holin_3_2 PF04550.12 KXS97445.1 - 0.49 11.0 3.0 0.64 10.6 1.1 2.2 2 0 0 2 2 2 0 Phage holin family 2 Ank_2 PF12796.7 KXS97446.1 - 1e-50 170.2 0.3 1.6e-10 41.4 0.0 5.8 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS97446.1 - 8.3e-42 141.0 5.2 2.6e-08 34.2 0.0 7.8 3 3 6 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS97446.1 - 5.2e-37 121.7 6.7 5e-06 26.5 0.0 9.9 9 0 0 9 9 9 8 Ankyrin repeat Ank PF00023.30 KXS97446.1 - 3.3e-31 106.4 12.8 0.0004 20.7 0.0 10.3 10 0 0 10 10 10 8 Ankyrin repeat HET PF06985.11 KXS97446.1 - 5.2e-31 108.0 0.3 1e-30 107.0 0.3 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_5 PF13857.6 KXS97446.1 - 9.1e-27 92.8 11.4 0.00032 20.9 0.0 8.5 1 1 9 10 10 10 8 Ankyrin repeats (many copies) VWA_3_C PF18571.1 KXS97446.1 - 1 9.3 4.5 35 4.4 0.0 4.1 5 0 0 5 5 5 0 von Willebrand factor type A C-terminal domain Ank_2 PF12796.7 KXS97447.1 - 5.8e-07 30.0 0.1 6.5e-07 29.9 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS97447.1 - 0.00045 20.5 0.1 0.53 11.0 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KXS97447.1 - 0.0025 18.1 0.4 0.1 13.0 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXS97447.1 - 0.0026 18.3 0.2 0.0036 17.8 0.2 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KXS97447.1 - 0.02 15.3 0.0 0.95 10.0 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat ATG16 PF08614.11 KXS97448.1 - 1.7e-27 97.0 14.0 2e-21 77.2 8.5 2.0 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) CEP63 PF17045.5 KXS97448.1 - 0.0016 18.4 3.1 0.002 18.1 3.1 1.1 1 0 0 1 1 1 1 Centrosomal protein of 63 kDa Golgin_A5 PF09787.9 KXS97448.1 - 0.0052 16.3 0.8 0.0052 16.3 0.8 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 Spc7 PF08317.11 KXS97448.1 - 0.022 13.6 0.5 0.021 13.7 0.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein APG6_N PF17675.1 KXS97448.1 - 0.031 14.8 2.8 0.04 14.5 2.8 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF3552 PF12072.8 KXS97448.1 - 0.036 13.5 4.3 0.041 13.3 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) YEATS PF03366.16 KXS97449.1 - 8.1e-17 61.0 0.0 1.7e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 YEATS family BET PF17035.5 KXS97449.1 - 2e-05 24.6 0.4 3.5e-05 23.9 0.4 1.4 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation SLX9 PF15341.6 KXS97449.1 - 0.011 16.1 0.4 0.02 15.3 0.4 1.3 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 HALZ PF02183.18 KXS97450.1 - 0.57 10.5 2.3 0.73 10.1 0.2 2.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper Ribosomal_L4 PF00573.22 KXS97451.1 - 7.9e-44 149.6 0.0 1.1e-43 149.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Fungal_trans PF04082.18 KXS97452.1 - 3.6e-16 59.0 3.2 5.6e-16 58.4 3.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 KXS97452.1 - 1e-07 32.1 13.3 2.8e-05 24.3 5.9 2.8 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KXS97452.1 - 0.00039 20.7 14.6 0.041 14.3 5.3 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS97452.1 - 0.00082 20.0 12.8 0.28 12.1 4.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KXS97452.1 - 0.0074 17.0 1.9 0.88 10.3 0.1 2.5 1 1 1 2 2 2 2 Zinc finger C2H2-type, 3 repeats Zn-ribbon_8 PF09723.10 KXS97452.1 - 0.84 9.8 4.6 2.2 8.5 4.6 1.7 1 0 0 1 1 1 0 Zinc ribbon domain DUF4449 PF14613.6 KXS97453.1 - 7.8e-69 231.0 5.3 7.8e-69 231.0 5.3 2.8 2 1 1 3 3 3 1 Protein of unknown function (DUF4449) SLAM PF06214.11 KXS97453.1 - 0.1 12.6 0.4 0.22 11.6 0.4 1.5 1 0 0 1 1 1 0 Signaling lymphocytic activation molecule (SLAM) protein DFF40 PF09230.10 KXS97453.1 - 0.25 10.9 5.4 0.092 12.3 0.8 2.2 2 0 0 2 2 2 0 DNA fragmentation factor 40 kDa HEPN_Swt1 PF18731.1 KXS97453.1 - 0.27 11.6 6.6 0.38 11.1 0.4 3.6 3 0 0 3 3 3 0 Swt1-like HEPN Endotoxin_N PF03945.14 KXS97453.1 - 0.73 9.5 7.7 0.42 10.3 1.6 3.0 3 0 0 3 3 3 0 delta endotoxin, N-terminal domain HI0933_like PF03486.14 KXS97453.1 - 1 8.0 6.1 0.57 8.8 1.0 2.3 2 0 0 2 2 2 0 HI0933-like protein Prp18 PF02840.15 KXS97453.1 - 2.5 8.1 13.1 3 7.9 0.0 3.8 3 1 1 4 4 4 0 Prp18 domain CREPT PF16566.5 KXS97453.1 - 4 7.6 7.1 0.75 10.0 1.3 2.7 3 0 0 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour Ran_BP1 PF00638.18 KXS97454.1 - 2.9e-50 169.6 1.1 5.9e-50 168.6 1.1 1.5 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 KXS97454.1 - 0.0002 21.2 0.1 0.0015 18.4 0.1 2.2 1 1 0 1 1 1 1 WH1 domain VID27_PH PF17747.1 KXS97454.1 - 0.0012 19.1 0.0 0.002 18.4 0.0 1.4 1 0 0 1 1 1 1 VID27 PH-like domain LAP1C PF05609.12 KXS97454.1 - 0.072 12.2 10.6 0.076 12.1 10.6 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) CDC27 PF09507.10 KXS97454.1 - 0.65 9.3 25.1 0.91 8.8 25.1 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF2967 PF11179.8 KXS97454.1 - 1.8 6.6 5.7 2.5 6.1 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) EF-hand_7 PF13499.6 KXS97455.1 - 2.7e-05 24.5 0.0 0.0056 17.1 0.0 2.7 1 1 2 3 3 3 2 EF-hand domain pair ORC6 PF05460.13 KXS97455.1 - 0.0003 20.2 0.9 0.00043 19.7 0.9 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) EF-hand_6 PF13405.6 KXS97455.1 - 0.00053 19.7 0.1 0.014 15.3 0.0 3.2 3 1 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 KXS97455.1 - 0.00097 18.5 0.1 0.036 13.6 0.0 3.4 3 1 0 3 3 3 1 EF hand EF-hand_9 PF14658.6 KXS97455.1 - 0.0066 16.8 0.0 0.073 13.4 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 KXS97455.1 - 0.015 15.2 0.0 0.87 9.5 0.0 2.9 2 2 1 3 3 3 0 EF-hand domain pair DUF1524 PF07510.11 KXS97455.1 - 0.056 13.3 0.1 0.69 9.8 0.0 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1524) EF-hand_7 PF13499.6 KXS97456.1 - 2.7e-05 24.5 0.0 0.0056 17.1 0.0 2.7 1 1 2 3 3 3 2 EF-hand domain pair ORC6 PF05460.13 KXS97456.1 - 0.0003 20.2 0.9 0.00043 19.7 0.9 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) EF-hand_6 PF13405.6 KXS97456.1 - 0.00053 19.7 0.1 0.014 15.3 0.0 3.2 3 1 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 KXS97456.1 - 0.00097 18.5 0.1 0.036 13.6 0.0 3.4 3 1 0 3 3 3 1 EF hand EF-hand_9 PF14658.6 KXS97456.1 - 0.0066 16.8 0.0 0.073 13.4 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 KXS97456.1 - 0.015 15.2 0.0 0.87 9.5 0.0 2.9 2 2 1 3 3 3 0 EF-hand domain pair DUF1524 PF07510.11 KXS97456.1 - 0.056 13.3 0.1 0.69 9.8 0.0 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1524) Arm PF00514.23 KXS97458.1 - 3.7e-97 315.8 15.4 4.1e-14 52.0 0.0 8.2 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 KXS97458.1 - 3.4e-28 97.9 0.7 8.9e-28 96.6 0.7 1.8 1 0 0 1 1 1 1 Importin beta binding domain Arm_3 PF16186.5 KXS97458.1 - 1.3e-23 82.3 1.6 3.2e-23 81.0 1.6 1.7 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_EZ PF13513.6 KXS97458.1 - 1.8e-22 79.4 7.9 1.5e-09 38.2 0.1 6.5 5 1 1 6 6 6 4 HEAT-like repeat HEAT_2 PF13646.6 KXS97458.1 - 6.6e-22 77.7 0.6 8.7e-10 38.9 0.1 5.2 1 1 4 5 5 5 3 HEAT repeats HEAT PF02985.22 KXS97458.1 - 1.7e-20 71.3 0.8 3.5e-06 26.8 0.0 7.2 8 0 0 8 8 7 4 HEAT repeat Arm_2 PF04826.13 KXS97458.1 - 2.6e-09 36.9 0.0 0.018 14.5 0.0 4.1 2 1 2 4 4 4 2 Armadillo-like Adaptin_N PF01602.20 KXS97458.1 - 3.8e-07 29.1 0.0 6.1e-05 21.8 0.0 2.2 1 1 1 2 2 2 2 Adaptin N terminal region V-ATPase_H_C PF11698.8 KXS97458.1 - 3e-05 24.1 0.0 1.4 9.1 0.0 4.6 3 2 2 5 5 5 2 V-ATPase subunit H NopRA1 PF16201.5 KXS97458.1 - 0.00051 19.7 0.0 0.74 9.4 0.0 4.0 1 1 2 4 4 4 1 Nucleolar pre-ribosomal-associated protein 1 RICTOR_V PF14668.6 KXS97458.1 - 0.00094 19.4 3.7 1.2 9.4 0.1 5.1 3 2 3 6 6 6 2 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.16 KXS97458.1 - 0.0035 17.9 6.0 0.22 12.3 0.2 4.8 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat Cnd1 PF12717.7 KXS97458.1 - 0.0085 16.1 0.0 4.8 7.2 0.0 3.2 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Glycos_trans_3N PF02885.17 KXS97458.1 - 0.17 11.8 0.1 36 4.3 0.0 3.5 4 0 0 4 4 3 0 Glycosyl transferase family, helical bundle domain NUSAP PF16006.5 KXS97458.1 - 2.1 8.1 6.2 3 7.5 6.2 1.2 1 0 0 1 1 1 0 Nucleolar and spindle-associated protein POT1PC PF16686.5 KXS97459.1 - 5.9e-34 117.2 0.1 3.1e-32 111.6 0.1 2.3 2 0 0 2 2 2 2 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 KXS97459.1 - 2e-18 66.6 0.0 2e-15 56.8 0.0 3.2 3 0 0 3 3 3 2 Telomeric single stranded DNA binding POT1/CDC13 IF3_N PF05198.16 KXS97460.1 - 1.2e-14 54.3 0.1 3.8e-14 52.7 0.1 2.0 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain PBP PF01161.20 KXS97460.1 - 5.3e-05 23.5 0.0 0.00011 22.5 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein IF3_C PF00707.22 KXS97460.1 - 0.00034 20.5 0.2 0.00034 20.5 0.2 2.5 3 0 0 3 3 3 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.6 KXS97460.1 - 0.00088 19.0 2.7 0.0037 16.9 2.7 2.0 1 1 0 1 1 1 1 Mitochondrial translation initiation factor MBD_C PF14048.6 KXS97460.1 - 0.0033 18.1 0.5 0.013 16.1 0.5 2.0 1 0 0 1 1 1 1 C-terminal domain of methyl-CpG binding protein 2 and 3 AAA_23 PF13476.6 KXS97460.1 - 0.79 10.2 9.7 1.7 9.1 0.8 2.4 2 0 0 2 2 2 0 AAA domain DUF4407 PF14362.6 KXS97460.1 - 2.4 7.4 9.5 0.95 8.8 2.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) TIM PF00121.18 KXS97461.1 - 2.2e-87 292.5 0.4 2.5e-87 292.3 0.4 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.14 KXS97461.1 - 0.043 13.3 0.1 0.066 12.7 0.1 1.3 1 0 0 1 1 1 0 CutC family Trp_ring PF18669.1 KXS97462.1 - 0.12 12.5 0.6 0.12 12.5 0.6 1.7 2 0 0 2 2 2 0 Trimeric autotransporter adhesin Trp ring domain DUF1264 PF06884.11 KXS97463.1 - 2e-78 261.9 0.1 2.4e-78 261.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) zf-rbx1 PF12678.7 KXS97465.1 - 1.1e-09 38.5 0.6 2.3e-09 37.4 0.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KXS97465.1 - 9.1e-09 35.5 5.8 5.8e-08 32.9 5.8 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KXS97465.1 - 3.6e-07 30.0 0.9 7.2e-07 29.0 0.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXS97465.1 - 5.3e-07 29.5 0.6 1e-06 28.6 0.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXS97465.1 - 3.4e-06 27.0 0.3 7.1e-05 22.8 0.0 2.7 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KXS97465.1 - 1.1e-05 25.1 6.6 2e-05 24.3 1.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXS97465.1 - 3.8e-05 23.4 1.4 8.4e-05 22.3 1.4 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 KXS97465.1 - 0.00024 20.7 7.5 0.0047 16.7 0.3 3.2 3 0 0 3 3 3 2 RING-like zinc finger zf-C3HC4_3 PF13920.6 KXS97465.1 - 0.0014 18.4 0.9 0.0014 18.4 0.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KXS97465.1 - 0.0051 16.4 0.5 0.012 15.2 0.5 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 KXS97465.1 - 0.0056 16.7 0.8 0.014 15.5 0.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger PQ-loop PF04193.14 KXS97465.1 - 0.0083 15.9 1.5 0.022 14.5 1.5 1.7 1 0 0 1 1 1 1 PQ loop repeat NINJA_B PF16136.5 KXS97465.1 - 0.077 13.4 4.1 0.15 12.5 4.1 1.4 1 0 0 1 1 1 0 Putative nuclear localisation signal DUF2921 PF11145.8 KXS97465.1 - 1.7 6.4 6.6 0.2 9.5 1.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2921) FANCL_C PF11793.8 KXS97465.1 - 5.2 7.3 5.2 24 5.2 5.2 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 KXS97465.1 - 5.8 7.1 5.7 0.68 10.1 1.1 1.8 2 0 0 2 2 2 0 RING-variant domain TMEM40 PF15817.5 KXS97465.1 - 9.4 6.0 5.7 5.4 6.8 1.5 2.3 2 0 0 2 2 2 0 Transmembrane protein 40 family Sulfotransfer_4 PF17784.1 KXS97466.1 - 1.1e-68 231.3 0.1 1.4e-68 231.0 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KXS97466.1 - 2.3e-05 24.9 0.2 0.0058 17.0 0.0 2.8 1 1 1 2 2 2 1 Sulfotransferase family DUF4167 PF13763.6 KXS97466.1 - 0.11 12.6 0.1 0.2 11.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4167) DnaJ_C PF01556.18 KXS97467.1 - 1e-35 123.0 0.1 1.6e-35 122.4 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KXS97467.1 - 1.4e-22 79.6 2.0 2.4e-22 78.8 2.0 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KXS97467.1 - 1.5e-14 54.1 17.8 2.7e-14 53.2 17.8 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KXS97467.1 - 0.0088 16.0 9.9 0.36 10.8 3.3 2.6 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KXS97467.1 - 0.065 13.3 8.0 1.3 9.1 1.1 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Cytochrome_C7 PF14522.6 KXS97467.1 - 0.7 9.9 9.1 0.76 9.8 2.2 2.4 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c DOT1 PF08123.13 KXS97468.1 - 3.3e-70 235.8 0.0 4.7e-70 235.3 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Imm51 PF15595.6 KXS97468.1 - 0.021 14.7 0.0 0.046 13.7 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 51 Nucleo_P87 PF07267.11 KXS97468.1 - 0.027 13.4 1.0 0.039 12.8 1.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 HAD_2 PF13419.6 KXS97468.1 - 0.048 13.8 0.0 1.1 9.3 0.0 2.3 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase Methyltransf_23 PF13489.6 KXS97468.1 - 0.068 13.0 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 KXS97468.1 - 0.12 11.7 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase AAA PF00004.29 KXS97474.1 - 5.3e-97 321.3 0.0 3.6e-47 160.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXS97474.1 - 6.8e-25 86.6 2.3 8.8e-13 47.8 0.5 2.8 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 KXS97474.1 - 6.6e-20 71.1 0.2 2e-19 69.5 0.2 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 KXS97474.1 - 6.2e-14 52.0 0.0 6.6e-06 25.9 0.0 3.1 3 1 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KXS97474.1 - 8.8e-14 52.0 0.0 1e-07 32.2 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KXS97474.1 - 3.1e-12 47.2 0.0 0.00015 22.2 0.0 4.3 2 2 1 3 3 3 2 AAA ATPase domain AAA_33 PF13671.6 KXS97474.1 - 5.6e-12 46.0 0.0 2.1e-05 24.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 KXS97474.1 - 1e-10 41.7 0.5 2e-05 24.6 0.1 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KXS97474.1 - 6.9e-09 35.4 0.8 0.0014 17.9 0.0 2.8 3 1 0 3 3 2 2 TIP49 P-loop domain AAA_22 PF13401.6 KXS97474.1 - 8e-09 35.9 0.4 0.06 13.6 0.0 4.1 2 2 1 3 3 3 2 AAA domain Mg_chelatase PF01078.21 KXS97474.1 - 3.6e-07 29.8 0.8 0.036 13.4 0.0 2.9 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI CDC48_2 PF02933.17 KXS97474.1 - 4.8e-07 29.5 0.0 1.1e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 IstB_IS21 PF01695.17 KXS97474.1 - 7.3e-07 29.1 0.0 0.026 14.3 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.22 KXS97474.1 - 7.4e-07 29.5 0.0 0.032 14.6 0.0 2.8 2 0 0 2 2 2 2 RNA helicase ATPase PF06745.13 KXS97474.1 - 7.8e-07 28.7 0.4 0.43 9.9 0.0 3.4 3 0 0 3 3 3 2 KaiC AAA_25 PF13481.6 KXS97474.1 - 1.1e-06 28.4 3.8 0.62 9.6 0.1 4.7 3 2 1 5 5 5 2 AAA domain AAA_18 PF13238.6 KXS97474.1 - 1.3e-06 29.0 0.0 0.055 14.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 KXS97474.1 - 2.6e-06 27.5 0.0 0.017 15.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KXS97474.1 - 7.8e-06 25.5 0.0 0.05 13.1 0.0 3.0 2 2 0 2 2 2 2 P-loop containing dynein motor region Vps4_C PF09336.10 KXS97474.1 - 1e-05 25.5 0.1 3.6e-05 23.7 0.1 2.0 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain ABC_tran PF00005.27 KXS97474.1 - 1.6e-05 25.5 0.0 0.42 11.1 0.0 4.2 3 1 0 3 3 3 1 ABC transporter AAA_24 PF13479.6 KXS97474.1 - 1.8e-05 24.5 0.0 0.13 11.9 0.0 2.8 3 0 0 3 3 2 2 AAA domain Parvo_NS1 PF01057.17 KXS97474.1 - 2.9e-05 23.3 0.1 0.099 11.7 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 DUF815 PF05673.13 KXS97474.1 - 3.1e-05 23.3 0.0 0.022 13.9 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 KXS97474.1 - 4.4e-05 23.3 0.1 0.45 10.2 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain AAA_28 PF13521.6 KXS97474.1 - 4.4e-05 23.8 0.0 0.31 11.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain Bac_DnaA PF00308.18 KXS97474.1 - 7.5e-05 22.7 0.0 0.14 12.0 0.0 2.6 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_17 PF13207.6 KXS97474.1 - 0.00016 22.1 0.1 0.6 10.5 0.0 3.5 3 0 0 3 3 3 1 AAA domain PhoH PF02562.16 KXS97474.1 - 0.00018 21.0 0.4 0.45 9.9 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein TsaE PF02367.17 KXS97474.1 - 0.00037 20.5 0.0 0.77 9.8 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 KXS97474.1 - 0.00039 20.3 0.0 1.3 8.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 KXS97474.1 - 0.00047 20.2 0.0 0.089 12.8 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_3 PF07726.11 KXS97474.1 - 0.00058 19.7 0.0 1.1 9.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 KXS97474.1 - 0.00072 18.9 0.0 0.91 8.7 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) ATPase_2 PF01637.18 KXS97474.1 - 0.0013 18.7 0.0 2.9 7.7 0.0 3.5 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea NACHT PF05729.12 KXS97474.1 - 0.0022 18.0 0.1 1.3 8.9 0.0 3.0 3 0 0 3 3 3 1 NACHT domain AAA_30 PF13604.6 KXS97474.1 - 0.0022 17.7 0.4 2.1 8.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KXS97474.1 - 0.0081 15.9 0.0 0.67 9.6 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 KXS97474.1 - 0.0088 16.4 1.0 9 6.6 0.0 3.5 3 1 0 4 4 2 0 AAA domain UFD1 PF03152.14 KXS97474.1 - 0.0089 15.5 0.0 0.045 13.2 0.0 1.9 1 1 1 2 2 2 1 Ubiquitin fusion degradation protein UFD1 NB-ARC PF00931.22 KXS97474.1 - 0.012 14.8 0.0 1.9 7.6 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain KAP_NTPase PF07693.14 KXS97474.1 - 0.015 14.6 0.2 0.93 8.7 0.0 2.8 2 2 0 2 2 2 0 KAP family P-loop domain Zeta_toxin PF06414.12 KXS97474.1 - 0.02 14.2 0.5 6.1 6.1 0.0 3.0 3 0 0 3 3 3 0 Zeta toxin NTPase_1 PF03266.15 KXS97474.1 - 0.023 14.6 0.5 4.1 7.3 0.0 3.5 3 0 0 3 3 3 0 NTPase Sigma54_activ_2 PF14532.6 KXS97474.1 - 0.024 14.8 0.0 3.8 7.6 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain IPT PF01745.16 KXS97474.1 - 0.031 13.6 0.0 2.4 7.5 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase Zot PF05707.12 KXS97474.1 - 0.036 13.7 0.0 2 8.0 0.0 3.1 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_6 PF12774.7 KXS97474.1 - 0.096 11.6 0.3 9 5.1 0.0 2.5 3 0 0 3 3 2 0 Hydrolytic ATP binding site of dynein motor region eIF-1a PF01176.19 KXS97474.1 - 0.14 12.0 1.4 0.6 10.0 0.3 2.4 1 1 1 2 2 2 0 Translation initiation factor 1A / IF-1 MFS_1 PF07690.16 KXS97475.1 - 2.9e-34 118.5 39.5 2.9e-34 118.5 39.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS97475.1 - 5.7e-11 41.9 12.9 5.7e-11 41.9 12.9 2.7 3 1 0 3 3 3 1 Sugar (and other) transporter Mobilization_B PF17511.2 KXS97475.1 - 0.22 11.9 1.3 0.54 10.6 1.3 1.6 1 0 0 1 1 1 0 Mobilization protein B NMO PF03060.15 KXS97476.1 - 3.9e-52 177.7 1.1 5.8e-52 177.1 1.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KXS97476.1 - 5e-11 42.2 0.0 1.1e-08 34.5 0.0 2.4 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KXS97476.1 - 0.00021 20.4 1.8 0.00021 20.4 1.8 2.0 2 0 0 2 2 2 1 FMN-dependent dehydrogenase RyR PF02026.16 KXS97477.1 - 8.6e-09 35.5 0.1 1.7e-06 28.1 0.0 2.4 2 0 0 2 2 2 2 RyR domain AAA_18 PF13238.6 KXS97477.1 - 0.0096 16.5 0.0 0.023 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 KXS97477.1 - 0.093 12.2 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_16 PF13191.6 KXS97477.1 - 0.1 13.0 0.0 0.5 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_17 PF13207.6 KXS97477.1 - 0.2 12.1 0.0 0.41 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Lipase_GDSL_2 PF13472.6 KXS97478.1 - 5.8e-21 75.7 0.1 7.6e-21 75.3 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXS97478.1 - 4.8e-15 56.1 0.0 6.1e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 KXS97478.1 - 0.066 13.3 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family CorA PF01544.18 KXS97479.1 - 5.7e-05 22.6 11.5 0.00019 20.9 0.5 2.4 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein EMP70 PF02990.16 KXS97479.1 - 0.12 11.0 0.2 0.18 10.4 0.2 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 Pro-kuma_activ PF09286.11 KXS97480.1 - 3.5e-49 166.8 0.6 3.5e-49 166.8 0.6 2.0 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain HET PF06985.11 KXS97480.1 - 6.7e-16 58.9 0.8 6.7e-16 58.9 0.8 2.1 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DnaJ PF00226.31 KXS97480.1 - 1.6e-13 50.6 0.3 3.9e-13 49.3 0.3 1.7 1 0 0 1 1 1 1 DnaJ domain Peptidase_S8 PF00082.22 KXS97480.1 - 0.0023 17.2 0.5 0.0041 16.4 0.5 1.3 1 0 0 1 1 1 1 Subtilase family CorA PF01544.18 KXS97481.1 - 5.7e-05 22.6 11.5 0.00019 20.9 0.5 2.4 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein EMP70 PF02990.16 KXS97481.1 - 0.12 11.0 0.2 0.18 10.4 0.2 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 Aldo_ket_red PF00248.21 KXS97482.1 - 6.8e-66 222.4 0.0 7.8e-66 222.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 KXS97483.1 - 6.6e-66 222.5 0.0 7.6e-66 222.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pec_lyase_C PF00544.19 KXS97484.1 - 1.3e-36 126.2 4.7 1.7e-36 125.8 4.7 1.1 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KXS97484.1 - 1.2e-06 28.5 8.2 0.00025 20.9 6.0 2.3 1 1 1 2 2 2 2 Right handed beta helix region EHN PF06441.12 KXS97485.1 - 1.5e-31 108.9 0.1 2.6e-31 108.2 0.1 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KXS97485.1 - 1.5e-06 28.0 0.1 4e-06 26.7 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Vps39_2 PF10367.9 KXS97486.1 - 0.00097 19.6 0.0 0.0029 18.0 0.0 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.20 KXS97486.1 - 0.001 18.9 0.0 0.081 12.8 0.0 2.7 3 0 0 3 3 3 1 Region in Clathrin and VPS Vps39_1 PF10366.9 KXS97486.1 - 0.0019 18.5 2.6 0.028 14.7 0.1 3.3 4 0 0 4 4 4 1 Vacuolar sorting protein 39 domain 1 WD40_like PF17005.5 KXS97486.1 - 0.19 11.0 0.0 0.33 10.2 0.0 1.3 1 0 0 1 1 1 0 WD40-like domain S4 PF01479.25 KXS97487.1 - 8.4e-13 47.8 0.0 1.6e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 KXS97487.1 - 0.0097 15.7 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 1 S4 domain DUF4239 PF14023.6 KXS97487.1 - 0.23 11.2 0.9 0.35 10.6 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Miga PF10265.9 KXS97487.1 - 2.1 7.2 8.8 3.2 6.6 8.8 1.3 1 0 0 1 1 1 0 Mitoguardin GET2 PF08690.10 KXS97487.1 - 5.7 6.5 9.6 8.6 5.9 9.6 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 CSRNP_N PF16019.5 KXS97487.1 - 9.7 6.0 7.6 5.5 6.8 5.4 1.6 1 1 1 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus MFS_1 PF07690.16 KXS97488.1 - 7.8e-20 71.1 17.4 6.1e-17 61.6 4.1 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 KXS97488.1 - 1.3e-16 60.8 6.1 1.8e-15 57.1 4.9 2.3 2 0 0 2 2 2 1 Nodulin-like p450 PF00067.22 KXS97489.1 - 3e-69 234.0 0.0 4.5e-69 233.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 La PF05383.17 KXS97490.1 - 6.4e-19 67.8 0.0 1.2e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 KXS97490.1 - 1.8e-08 34.0 0.5 3.9e-08 33.0 0.5 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MBOAT_2 PF13813.6 KXS97491.1 - 2.7e-13 50.0 0.3 8e-13 48.5 0.3 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Septin PF00735.18 KXS97492.1 - 2e-121 404.6 0.1 2e-121 404.6 0.1 1.8 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KXS97492.1 - 2.9e-08 33.8 1.0 5.4e-08 32.9 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KXS97492.1 - 2.4e-06 27.2 1.2 0.00018 21.1 0.0 2.9 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 KXS97492.1 - 0.00017 22.1 2.4 0.021 15.4 0.0 2.7 3 0 0 3 3 3 1 ABC transporter Roc PF08477.13 KXS97492.1 - 0.00027 21.1 0.0 0.00062 20.0 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 KXS97492.1 - 0.00062 19.2 1.1 0.0013 18.2 0.0 2.0 2 0 0 2 2 2 1 AIG1 family RsgA_GTPase PF03193.16 KXS97492.1 - 0.0012 18.8 0.7 0.0012 18.8 0.7 3.5 3 1 0 3 3 3 1 RsgA GTPase AAA_16 PF13191.6 KXS97492.1 - 0.0018 18.7 0.0 0.0056 17.1 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Ras PF00071.22 KXS97492.1 - 0.0032 17.1 0.0 0.011 15.3 0.0 1.9 1 0 0 1 1 1 1 Ras family AAA_22 PF13401.6 KXS97492.1 - 0.0053 17.0 0.7 0.019 15.3 0.0 2.4 2 2 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KXS97492.1 - 0.01 15.6 0.0 0.024 14.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 KXS97492.1 - 0.04 13.4 0.0 0.08 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 KXS97492.1 - 0.055 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_24 PF13479.6 KXS97492.1 - 0.067 12.9 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KXS97492.1 - 0.075 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 KXS97492.1 - 0.08 13.3 0.5 0.4 11.1 0.0 2.4 3 0 0 3 3 3 0 RNA helicase Exonuc_VII_L PF02601.15 KXS97492.1 - 0.28 10.7 5.9 0.51 9.9 5.9 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit ATP_bind_1 PF03029.17 KXS97492.1 - 0.34 10.6 5.9 1.3 8.7 0.0 3.1 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 KXS97492.1 - 0.41 10.7 12.3 0.98 9.5 0.1 3.7 2 2 1 3 3 3 0 Dynamin family DUF87 PF01935.17 KXS97492.1 - 0.6 10.2 5.5 5.3 7.1 0.0 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain Atg14 PF10186.9 KXS97492.1 - 1.2 8.1 8.8 2 7.5 8.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0242 PF06785.11 KXS97492.1 - 3.2 7.8 15.5 5.8 7.0 15.5 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Septin PF00735.18 KXS97493.1 - 2e-121 404.6 0.1 2e-121 404.6 0.1 1.8 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KXS97493.1 - 2.9e-08 33.8 1.0 5.4e-08 32.9 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KXS97493.1 - 2.4e-06 27.2 1.2 0.00018 21.1 0.0 2.9 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 KXS97493.1 - 0.00017 22.1 2.4 0.021 15.4 0.0 2.7 3 0 0 3 3 3 1 ABC transporter Roc PF08477.13 KXS97493.1 - 0.00027 21.1 0.0 0.00062 20.0 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 KXS97493.1 - 0.00062 19.2 1.1 0.0013 18.2 0.0 2.0 2 0 0 2 2 2 1 AIG1 family RsgA_GTPase PF03193.16 KXS97493.1 - 0.0012 18.8 0.7 0.0012 18.8 0.7 3.5 3 1 0 3 3 3 1 RsgA GTPase AAA_16 PF13191.6 KXS97493.1 - 0.0018 18.7 0.0 0.0056 17.1 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Ras PF00071.22 KXS97493.1 - 0.0032 17.1 0.0 0.011 15.3 0.0 1.9 1 0 0 1 1 1 1 Ras family AAA_22 PF13401.6 KXS97493.1 - 0.0053 17.0 0.7 0.019 15.3 0.0 2.4 2 2 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KXS97493.1 - 0.01 15.6 0.0 0.024 14.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 KXS97493.1 - 0.04 13.4 0.0 0.08 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 KXS97493.1 - 0.055 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_24 PF13479.6 KXS97493.1 - 0.067 12.9 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KXS97493.1 - 0.075 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 KXS97493.1 - 0.08 13.3 0.5 0.4 11.1 0.0 2.4 3 0 0 3 3 3 0 RNA helicase Exonuc_VII_L PF02601.15 KXS97493.1 - 0.28 10.7 5.9 0.51 9.9 5.9 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit ATP_bind_1 PF03029.17 KXS97493.1 - 0.34 10.6 5.9 1.3 8.7 0.0 3.1 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 KXS97493.1 - 0.41 10.7 12.3 0.98 9.5 0.1 3.7 2 2 1 3 3 3 0 Dynamin family DUF87 PF01935.17 KXS97493.1 - 0.6 10.2 5.5 5.3 7.1 0.0 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain Atg14 PF10186.9 KXS97493.1 - 1.2 8.1 8.8 2 7.5 8.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0242 PF06785.11 KXS97493.1 - 3.2 7.8 15.5 5.8 7.0 15.5 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Septin PF00735.18 KXS97494.1 - 1.6e-121 405.0 0.1 1.6e-121 405.0 0.1 1.8 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KXS97494.1 - 2.4e-08 34.1 1.0 4.4e-08 33.2 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KXS97494.1 - 1.7e-06 27.7 1.3 0.00016 21.3 0.0 2.9 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 KXS97494.1 - 0.00011 22.7 2.3 0.017 15.6 0.0 2.7 3 0 0 3 3 3 1 ABC transporter Roc PF08477.13 KXS97494.1 - 0.00022 21.4 0.0 0.00054 20.2 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 KXS97494.1 - 0.001 18.4 0.0 0.001 18.4 0.0 2.1 2 1 1 3 3 3 1 AIG1 family RsgA_GTPase PF03193.16 KXS97494.1 - 0.0011 19.0 0.6 0.0011 19.0 0.6 3.6 3 1 0 3 3 3 1 RsgA GTPase AAA_16 PF13191.6 KXS97494.1 - 0.0016 18.9 0.0 0.0049 17.3 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Ras PF00071.22 KXS97494.1 - 0.0026 17.4 0.0 0.0095 15.5 0.0 2.0 1 0 0 1 1 1 1 Ras family AAA_22 PF13401.6 KXS97494.1 - 0.0048 17.2 1.0 0.016 15.5 0.0 2.4 2 2 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KXS97494.1 - 0.01 15.6 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_7 PF12775.7 KXS97494.1 - 0.035 13.6 0.0 0.071 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 KXS97494.1 - 0.047 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_24 PF13479.6 KXS97494.1 - 0.056 13.2 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KXS97494.1 - 0.064 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 KXS97494.1 - 0.065 13.6 0.6 0.36 11.2 0.0 2.5 3 0 0 3 3 3 0 RNA helicase ATP_bind_1 PF03029.17 KXS97494.1 - 0.24 11.2 5.9 1.1 9.0 0.0 3.1 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein Exonuc_VII_L PF02601.15 KXS97494.1 - 0.26 10.8 6.0 0.48 9.9 6.0 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Dynamin_N PF00350.23 KXS97494.1 - 0.35 10.9 12.6 0.86 9.6 0.1 3.8 2 2 0 3 3 3 0 Dynamin family DUF87 PF01935.17 KXS97494.1 - 0.45 10.6 5.5 4.7 7.2 0.0 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain Atg14 PF10186.9 KXS97494.1 - 0.81 8.7 8.4 1.2 8.1 8.4 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3987 PF13148.6 KXS97494.1 - 1.7 7.6 0.0 1.7 7.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) UPF0242 PF06785.11 KXS97494.1 - 2.7 8.1 15.5 5 7.2 15.5 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Exo70 PF03081.15 KXS97495.1 - 1.3e-90 304.2 0.0 2.3e-90 303.4 0.0 1.4 1 0 0 1 1 1 1 Exo70 exocyst complex subunit FlgN PF05130.12 KXS97495.1 - 0.96 9.9 6.6 22 5.5 4.1 3.1 3 1 0 3 3 3 0 FlgN protein CASP_C PF08172.12 KXS97496.1 - 5.9e-92 307.6 0.0 5.9e-92 307.6 0.0 3.8 2 2 2 4 4 4 1 CASP C terminal Cep57_MT_bd PF06657.13 KXS97496.1 - 0.0017 18.8 32.2 0.018 15.5 3.0 5.4 5 0 0 5 5 5 3 Centrosome microtubule-binding domain of Cep57 DivIC PF04977.15 KXS97496.1 - 0.02 14.7 1.4 0.02 14.7 1.4 7.5 7 2 1 8 8 8 0 Septum formation initiator DUF2946 PF11162.8 KXS97496.1 - 0.039 14.6 2.5 0.14 12.8 2.5 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) Phage_GP20 PF06810.11 KXS97496.1 - 0.098 12.5 53.7 0.19 11.5 11.0 5.6 5 1 1 6 6 6 0 Phage minor structural protein GP20 GTP-bdg_M PF16360.5 KXS97496.1 - 0.74 10.4 21.8 9.8 6.9 3.2 5.5 4 1 0 4 4 4 0 GTP-binding GTPase Middle Region Trimer_CC PF08954.11 KXS97496.1 - 4.3 7.0 18.2 0.75 9.4 3.0 4.0 3 0 0 3 3 3 0 Trimerisation motif Methyltransf_11 PF08241.12 KXS97497.1 - 2.8e-12 47.1 0.0 4.5e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS97497.1 - 2.8e-10 40.8 0.0 4.8e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXS97497.1 - 2e-09 37.5 0.0 3.6e-09 36.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS97497.1 - 4.5e-07 29.8 0.0 7.2e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS97497.1 - 1.7e-06 28.6 0.0 3e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KXS97497.1 - 0.033 13.1 0.0 0.099 11.5 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) DnaB_bind PF10410.9 KXS97497.1 - 0.062 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 DnaB-helicase binding domain of primase MetW PF07021.12 KXS97497.1 - 0.17 11.5 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PLA2_B PF01735.18 KXS97498.1 - 1.8e-25 89.3 0.0 2.9e-25 88.7 0.0 1.3 1 0 0 1 1 1 1 Lysophospholipase catalytic domain BTB PF00651.31 KXS97499.1 - 3.2e-06 27.4 0.0 6.2e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain RRM_1 PF00076.22 KXS97505.1 - 2.8e-20 71.9 0.0 4e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXS97505.1 - 0.0016 18.1 0.0 0.0022 17.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Filament PF00038.21 KXS97506.1 - 0.0098 15.5 7.2 0.0098 15.5 7.2 2.1 3 0 0 3 3 2 1 Intermediate filament protein DUF5082 PF16888.5 KXS97506.1 - 0.022 15.0 16.5 0.059 13.6 0.3 4.0 2 1 2 4 4 4 0 Domain of unknown function (DUF5082) EzrA PF06160.12 KXS97506.1 - 0.03 12.5 3.8 0.057 11.6 3.8 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DMPK_coil PF08826.10 KXS97506.1 - 0.051 13.7 0.4 0.051 13.7 0.4 3.0 2 0 0 2 2 2 0 DMPK coiled coil domain like RPW8 PF05659.11 KXS97506.1 - 0.099 12.3 1.7 0.13 12.0 0.3 1.9 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Allexi_40kDa PF05549.11 KXS97506.1 - 0.12 11.8 2.7 0.18 11.3 1.0 2.0 2 0 0 2 2 2 0 Allexivirus 40kDa protein DUF1043 PF06295.12 KXS97506.1 - 0.16 11.9 6.7 0.037 14.0 2.9 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF1043) DHR10 PF18595.1 KXS97506.1 - 0.19 11.8 18.4 0.03 14.4 11.3 2.6 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain HMMR_N PF15905.5 KXS97506.1 - 0.21 11.1 11.9 0.093 12.2 7.0 2.3 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF3490 PF11995.8 KXS97506.1 - 0.27 11.1 3.5 5.4 6.8 2.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3490) SOGA PF11365.8 KXS97506.1 - 0.29 12.3 8.3 0.73 11.0 0.1 3.3 2 1 2 4 4 4 0 Protein SOGA Baculo_PEP_C PF04513.12 KXS97506.1 - 0.3 11.1 6.5 0.73 9.9 1.2 2.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PRKG1_interact PF15898.5 KXS97506.1 - 0.39 11.6 10.4 0.46 11.4 5.9 2.9 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain ABC_tran_CTD PF16326.5 KXS97506.1 - 0.5 10.7 19.1 0.36 11.1 4.5 3.9 3 1 1 4 4 3 0 ABC transporter C-terminal domain YabA PF06156.13 KXS97506.1 - 0.62 10.7 2.6 19 6.0 0.7 2.7 2 0 0 2 2 2 0 Initiation control protein YabA CLZ PF16526.5 KXS97506.1 - 1 9.8 16.5 0.14 12.5 3.6 3.8 4 0 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Translin PF01997.16 KXS97506.1 - 1.2 9.1 5.3 2.8 7.9 3.7 2.0 2 0 0 2 2 2 0 Translin family SH3BP5 PF05276.14 KXS97506.1 - 1.2 8.9 10.6 0.55 10.0 2.1 3.4 2 2 1 3 3 3 0 SH3 domain-binding protein 5 (SH3BP5) Prominin PF05478.11 KXS97506.1 - 1.6 6.6 3.8 10 4.0 4.8 1.7 2 1 0 2 2 2 0 Prominin TPR_MLP1_2 PF07926.12 KXS97506.1 - 1.7 8.7 18.0 0.91 9.6 9.2 3.0 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein ADIP PF11559.8 KXS97506.1 - 1.7 8.7 14.3 0.89 9.6 8.7 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding NPV_P10 PF05531.12 KXS97506.1 - 1.9 9.0 5.3 2.5 8.6 2.0 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Spc24 PF08286.11 KXS97506.1 - 2.1 8.7 6.9 0.98 9.7 2.1 2.7 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 YlqD PF11068.8 KXS97506.1 - 2.7 8.4 13.3 0.24 11.8 7.3 2.3 3 0 0 3 3 2 0 YlqD protein FlaC_arch PF05377.11 KXS97506.1 - 2.9 8.3 6.3 19 5.7 0.7 3.3 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Seryl_tRNA_N PF02403.22 KXS97506.1 - 6.7 7.0 18.9 0.033 14.4 5.9 3.3 3 1 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Stathmin PF00836.19 KXS97506.1 - 8 6.4 12.8 15 5.6 0.2 2.5 2 0 0 2 2 2 0 Stathmin family DUF5320 PF17253.2 KXS97506.1 - 9.1 7.4 7.1 1.1 10.4 0.6 2.8 3 0 0 3 3 1 0 Family of unknown function (DUF5320) WD40 PF00400.32 KXS97508.1 - 1.1e-11 45.1 36.4 0.0014 19.4 0.3 11.8 13 0 0 13 13 13 4 WD domain, G-beta repeat WD40_3 PF15911.5 KXS97508.1 - 0.0058 16.6 0.0 0.21 11.6 0.0 3.0 3 0 0 3 3 3 1 WD domain, G-beta repeat ETRAMP PF09716.10 KXS97508.1 - 0.12 12.4 0.1 0.32 11.1 0.1 1.7 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) WD40 PF00400.32 KXS97509.1 - 4.8e-10 39.9 4.0 0.017 16.0 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat MccV PF17508.2 KXS97510.1 - 0.15 12.6 10.3 0.16 12.6 0.5 3.5 3 0 0 3 3 3 0 Microcin V bacteriocin zf-C2H2 PF00096.26 KXS97511.1 - 1.8e-06 28.0 18.4 0.01 16.2 4.3 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS97511.1 - 9.3e-06 26.1 16.0 0.23 12.4 0.8 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KXS97511.1 - 0.61 10.2 5.7 0.25 11.5 2.0 2.0 1 1 1 2 2 2 0 Aberrant zinc-finger zf-C2H2_2 PF12756.7 KXS97511.1 - 0.64 10.4 6.8 2.2 8.7 0.1 2.5 1 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-UBP PF02148.19 KXS97511.1 - 9.4 6.7 14.2 9 6.7 11.3 2.4 2 1 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein LIM PF00412.22 KXS97512.1 - 3.9e-25 87.9 31.9 7.1e-10 39.0 4.8 3.8 4 0 0 4 4 4 3 LIM domain Paired_CXXCH_1 PF09699.10 KXS97512.1 - 0.085 12.6 0.1 0.085 12.6 0.1 3.5 2 1 1 3 3 3 0 Doubled CXXCH motif (Paired_CXXCH_1) zf-C2H2 PF00096.26 KXS97513.1 - 1.6e-06 28.3 18.4 0.0098 16.3 4.3 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS97513.1 - 7.8e-06 26.3 16.0 0.22 12.5 0.8 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KXS97513.1 - 0.38 11.1 6.3 1.9 8.8 0.1 2.5 1 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_aberr PF17017.5 KXS97513.1 - 0.51 10.5 5.6 0.21 11.7 1.8 2.0 1 1 1 2 2 2 0 Aberrant zinc-finger zf-UBP PF02148.19 KXS97513.1 - 7.1 7.0 13.9 7.3 7.0 11.1 2.4 2 1 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein zf-C2H2 PF00096.26 KXS97514.1 - 1.6e-06 28.3 18.4 0.0098 16.3 4.3 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS97514.1 - 7.8e-06 26.3 16.0 0.22 12.5 0.8 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KXS97514.1 - 0.38 11.1 6.3 1.9 8.8 0.1 2.5 1 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_aberr PF17017.5 KXS97514.1 - 0.51 10.5 5.6 0.21 11.7 1.8 2.0 1 1 1 2 2 2 0 Aberrant zinc-finger zf-UBP PF02148.19 KXS97514.1 - 7.1 7.0 13.9 7.3 7.0 11.1 2.4 2 1 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein GPI-anchored PF10342.9 KXS97515.1 - 4.6e-22 78.6 1.6 4.6e-22 78.6 1.6 2.0 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF2838 PF10998.8 KXS97516.1 - 2.2e-41 140.6 11.4 2.2e-41 140.6 11.4 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) HAUS4 PF14735.6 KXS97516.1 - 0.13 12.0 1.4 0.23 11.1 1.4 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 CCDC-167 PF15188.6 KXS97516.1 - 0.37 11.2 7.4 1.1 9.6 0.1 3.3 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 DUF2838 PF10998.8 KXS97517.1 - 3.5e-42 143.1 11.6 3.5e-42 143.1 11.6 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) HAUS4 PF14735.6 KXS97517.1 - 0.13 12.0 1.4 0.23 11.1 1.4 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 CCDC-167 PF15188.6 KXS97517.1 - 0.37 11.2 7.4 1.1 9.6 0.1 3.3 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 mRNA_triPase PF02940.15 KXS97518.1 - 4.7e-44 150.7 0.2 6.6e-44 150.3 0.2 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Band_7 PF01145.25 KXS97519.1 - 9e-30 104.0 0.4 9e-30 104.0 0.4 1.6 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_C PF16200.5 KXS97519.1 - 1.1e-24 86.2 1.3 3e-24 84.9 1.3 1.8 1 0 0 1 1 1 1 C-terminal region of band_7 Pox_A11 PF05061.13 KXS97519.1 - 0.011 15.0 0.2 0.019 14.2 0.2 1.4 1 0 0 1 1 1 0 Poxvirus A11 Protein Rotamase PF00639.21 KXS97519.1 - 3.6 8.6 7.5 0.67 10.9 1.3 2.5 1 1 1 2 2 2 0 PPIC-type PPIASE domain Abhydrolase_6 PF12697.7 KXS97520.1 - 0.00031 21.4 0.0 0.0029 18.3 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXS97520.1 - 0.00043 19.6 0.0 0.0013 18.0 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KXS97520.1 - 0.00065 19.2 0.0 0.95 8.9 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KXS97520.1 - 0.00082 19.1 0.0 0.0032 17.1 0.0 2.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 KXS97520.1 - 0.001 18.7 1.0 0.0041 16.7 0.0 2.2 3 0 0 3 3 3 1 X-Pro dipeptidyl-peptidase (S15 family) Oleosin PF01277.17 KXS97520.1 - 0.042 13.6 0.3 0.73 9.6 0.0 2.5 3 0 0 3 3 3 0 Oleosin RPN2_C PF18004.1 KXS97521.1 - 7.7e-57 191.7 4.6 1.4e-56 190.8 4.6 1.5 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 KXS97521.1 - 6.5e-43 143.0 18.8 3e-10 40.0 0.0 8.5 7 0 0 7 7 7 6 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KXS97521.1 - 1.5e-21 76.5 1.8 6.7e-15 55.2 0.0 4.7 3 1 3 6 6 6 4 HEAT repeats HEAT PF02985.22 KXS97521.1 - 7.3e-06 25.8 0.6 10 6.7 0.1 6.3 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.6 KXS97521.1 - 0.00037 20.9 0.3 0.36 11.4 0.0 4.0 2 1 1 3 3 3 2 HEAT-like repeat Cnd1 PF12717.7 KXS97521.1 - 0.02 14.9 0.1 0.99 9.4 0.0 3.1 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 KXS97521.1 - 0.022 15.4 0.5 10 7.1 0.0 4.2 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat Asp_Glu_race PF01177.22 KXS97522.1 - 0.00018 21.4 0.2 0.0004 20.3 0.2 1.5 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase DUF212 PF02681.14 KXS97522.1 - 0.14 12.3 0.0 3.5 7.8 0.0 2.3 2 0 0 2 2 2 0 Divergent PAP2 family Peptidase_C14 PF00656.22 KXS97523.1 - 8.3e-06 25.9 0.0 1.2e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 KXS97523.1 - 0.0019 18.2 1.7 0.13 12.2 0.6 3.2 2 1 0 2 2 2 1 Raptor N-terminal CASPase like domain SMC_N PF02463.19 KXS97524.1 - 1.7e-56 191.2 3.5 8.1e-55 185.6 3.5 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KXS97524.1 - 2.4e-26 92.3 0.0 1.1e-25 90.3 0.0 2.2 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KXS97524.1 - 2.3e-11 44.1 10.2 1.1e-05 25.5 0.0 3.7 4 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KXS97524.1 - 1.9e-08 34.4 9.7 1.9e-08 34.4 9.7 4.2 2 2 1 3 3 1 1 AAA ATPase domain AAA_29 PF13555.6 KXS97524.1 - 2.7e-08 33.4 0.0 5.7e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KXS97524.1 - 0.00046 20.8 36.5 0.00046 20.8 36.5 8.1 2 2 2 4 4 2 1 AAA domain ATG16 PF08614.11 KXS97524.1 - 0.002 18.4 107.9 0.011 15.9 3.4 7.3 4 2 2 6 6 6 4 Autophagy protein 16 (ATG16) SbcCD_C PF13558.6 KXS97524.1 - 0.0043 17.2 0.0 0.025 14.8 0.0 2.4 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Golgin_A5 PF09787.9 KXS97524.1 - 0.0049 16.4 6.8 0.0049 16.4 6.8 6.7 2 2 4 7 7 7 2 Golgin subfamily A member 5 TRAF_BIRC3_bd PF16673.5 KXS97524.1 - 0.0095 15.7 0.2 0.0095 15.7 0.2 8.1 7 3 2 9 9 9 1 TNF receptor-associated factor BIRC3 binding domain Bacillus_HBL PF05791.11 KXS97524.1 - 0.013 15.3 51.3 0.47 10.3 5.9 6.8 5 2 1 6 6 6 0 Bacillus haemolytic enterotoxin (HBL) DUF2939 PF11159.8 KXS97524.1 - 0.16 12.4 1.0 0.63 10.5 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2939) ABC_tran PF00005.27 KXS97524.1 - 0.66 10.5 0.0 0.66 10.5 0.0 6.3 4 3 0 4 4 2 0 ABC transporter NumbF PF06311.12 KXS97524.1 - 3 8.5 7.7 4.4 7.9 1.2 3.6 3 0 0 3 3 2 0 NUMB domain Baculo_PEP_C PF04513.12 KXS97524.1 - 5.8 6.9 23.9 5.6 7.0 0.0 6.0 6 2 1 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 KXS97524.1 - 9.9 4.9 122.6 0.49 9.2 11.2 7.4 3 2 6 9 9 9 0 Spc7 kinetochore protein MANEC PF07502.14 KXS97525.1 - 0.0084 16.4 0.0 0.015 15.5 0.0 1.3 1 0 0 1 1 1 1 MANEC domain TarH PF02203.15 KXS97525.1 - 0.022 14.7 0.2 0.034 14.1 0.2 1.2 1 0 0 1 1 1 0 Tar ligand binding domain homologue Tad PF13400.6 KXS97525.1 - 0.24 11.7 3.5 0.44 10.9 3.5 1.3 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like Bacteriocin_IIc PF10439.9 KXS97525.1 - 6.6 6.9 9.5 4.8 7.4 3.2 2.3 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide FAA_hydrolase PF01557.18 KXS97526.1 - 1.4e-50 172.0 0.0 1.9e-50 171.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 KXS97526.1 - 3e-27 94.9 0.0 1.1e-26 93.1 0.0 1.8 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal F-box PF00646.33 KXS97527.1 - 0.047 13.6 0.8 1.8 8.6 0.1 2.8 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 KXS97527.1 - 0.055 13.4 1.2 0.18 11.7 0.0 2.6 3 1 0 3 3 3 0 F-box-like SDA1 PF05285.12 KXS97527.1 - 0.88 8.9 11.4 1.4 8.3 11.4 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 KXS97527.1 - 6.1 6.1 13.1 11 5.3 13.1 1.3 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 KXS97527.1 - 7.6 4.6 17.4 1.8 6.6 14.0 1.6 2 0 0 2 2 2 0 Nop14-like family NOA36 PF06524.12 KXS97527.1 - 9.8 5.4 16.9 19 4.4 16.9 1.4 1 0 0 1 1 1 0 NOA36 protein DUF3431 PF11913.8 KXS97528.1 - 1.2e-84 283.4 0.0 1.8e-84 282.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) DUF2975 PF11188.8 KXS97531.1 - 0.043 13.7 5.5 0.042 13.7 4.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2975) ABC2_membrane_3 PF12698.7 KXS97531.1 - 0.21 10.7 5.8 0.31 10.1 5.8 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2975 PF11188.8 KXS97532.1 - 0.043 13.7 5.5 0.042 13.7 4.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2975) ABC2_membrane_3 PF12698.7 KXS97532.1 - 0.21 10.7 5.8 0.31 10.1 5.8 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2975 PF11188.8 KXS97533.1 - 0.043 13.7 5.5 0.042 13.7 4.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2975) ABC2_membrane_3 PF12698.7 KXS97533.1 - 0.21 10.7 5.8 0.31 10.1 5.8 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Ion_trans PF00520.31 KXS97534.1 - 7.2e-127 421.7 87.1 6.6e-44 150.0 3.0 4.9 4 1 0 4 4 4 4 Ion transport protein GPHH PF16905.5 KXS97534.1 - 0.00017 21.3 0.0 0.00052 19.7 0.0 1.9 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated EF-hand_1 PF00036.32 KXS97534.1 - 0.00048 19.5 0.0 0.0016 17.8 0.0 2.0 2 0 0 2 2 2 1 EF hand PKD_channel PF08016.12 KXS97534.1 - 0.0017 17.1 7.0 0.0017 17.1 7.0 6.4 6 1 1 7 7 7 3 Polycystin cation channel EF-hand_6 PF13405.6 KXS97534.1 - 0.0031 17.3 0.0 0.013 15.3 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KXS97534.1 - 0.028 14.9 0.0 0.087 13.3 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair DUF2976 PF11190.8 KXS97534.1 - 2.4 8.0 6.6 7 6.5 0.0 4.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2976) HTH_11 PF08279.12 KXS97547.1 - 0.07 13.1 0.0 21 5.2 0.0 2.6 2 0 0 2 2 2 0 HTH domain TP_methylase PF00590.20 KXS97547.1 - 0.098 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Tetrapyrrole (Corrin/Porphyrin) Methylases Calcipressin PF04847.12 KXS97548.1 - 1.6e-43 148.6 0.7 2.5e-43 148.0 0.7 1.3 1 0 0 1 1 1 1 Calcipressin Phage_cap_P2 PF05125.12 KXS97548.1 - 0.13 11.2 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Phage major capsid protein, P2 family B12D PF06522.11 KXS97549.1 - 0.0038 17.0 0.0 0.0062 16.3 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit ThrE PF06738.12 KXS97549.1 - 0.038 13.4 0.0 0.039 13.3 0.0 1.1 1 0 0 1 1 1 0 Putative threonine/serine exporter CMD PF02627.20 KXS97550.1 - 2e-08 34.2 0.0 1.4e-07 31.5 0.0 2.1 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family p450 PF00067.22 KXS97551.1 - 5.4e-67 226.5 0.0 6.8e-67 226.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.19 KXS97552.1 - 4.6e-14 52.4 1.7 1e-11 44.7 1.7 3.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXS97552.1 - 3.9e-10 39.4 0.1 0.00037 19.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXS97552.1 - 1.4e-08 34.3 0.1 2.7e-08 33.3 0.1 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXS97552.1 - 1.6e-07 31.2 2.3 0.0039 16.8 0.4 2.5 1 1 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 KXS97552.1 - 6.6e-07 28.4 0.2 0.0011 17.7 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.7 KXS97552.1 - 3.2e-05 23.5 0.1 6.3e-05 22.5 0.1 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXS97552.1 - 7e-05 23.0 0.1 0.00024 21.3 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KXS97552.1 - 0.00011 21.4 0.0 0.007 15.5 0.1 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KXS97552.1 - 0.0002 20.8 0.0 0.0023 17.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXS97552.1 - 0.0012 18.0 0.4 0.45 9.5 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 KXS97552.1 - 0.0029 16.9 0.0 0.007 15.7 0.0 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KXS97552.1 - 0.0031 18.0 0.0 0.12 13.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXS97552.1 - 0.01 15.1 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.24 KXS97552.1 - 0.013 14.8 0.0 1.7 7.8 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 KXS97552.1 - 0.098 12.6 0.0 8.9 6.3 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding DDE_Tnp_IS1595 PF12762.7 KXS97552.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 ISXO2-like transposase domain 3HCDH_N PF02737.18 KXS97552.1 - 0.21 11.5 0.1 0.52 10.2 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain p450 PF00067.22 KXS97553.1 - 3.7e-56 190.8 0.0 5.2e-56 190.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Stirrup PF09061.6 KXS97553.1 - 0.05 13.8 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Stirrup RA PF00788.23 KXS97555.1 - 0.017 15.8 2.2 1.2 9.8 0.1 2.5 2 1 0 2 2 2 0 Ras association (RalGDS/AF-6) domain Zip PF02535.22 KXS97557.1 - 5e-05 22.7 0.0 0.00011 21.5 0.0 1.6 1 0 0 1 1 1 1 ZIP Zinc transporter Endonuclease_NS PF01223.23 KXS97558.1 - 0.0007 19.5 2.1 0.002 18.0 2.2 1.7 2 0 0 2 2 2 1 DNA/RNA non-specific endonuclease Pneumo_att_G PF05539.11 KXS97558.1 - 9.9 5.6 7.9 17 4.9 7.9 1.3 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Fungal_trans PF04082.18 KXS97559.1 - 8.5e-30 103.7 0.0 1.4e-29 103.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS97559.1 - 4.4e-08 33.1 14.9 7.7e-08 32.3 14.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNB PF00773.19 KXS97560.1 - 4.3e-97 325.3 0.2 6.5e-97 324.8 0.2 1.3 1 0 0 1 1 1 1 RNB domain Rrp44_S1 PF17215.3 KXS97560.1 - 2.1e-32 110.9 0.3 5.2e-32 109.7 0.3 1.7 1 0 0 1 1 1 1 S1 domain Rrp44_CSD1 PF17216.3 KXS97560.1 - 1e-30 106.4 0.0 2.2e-30 105.3 0.0 1.6 1 0 0 1 1 1 1 Rrp44-like cold shock domain OB_Dis3 PF17849.1 KXS97560.1 - 8.9e-21 73.7 0.0 3.2e-20 71.9 0.0 2.0 2 0 0 2 2 2 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 KXS97560.1 - 7.6e-09 35.6 0.0 2.8e-05 24.2 0.0 3.2 3 0 0 3 3 3 2 Cold shock domain PIN_4 PF13638.6 KXS97560.1 - 3.8e-06 27.2 1.6 2e-05 24.9 0.1 3.0 2 2 1 3 3 3 1 PIN domain Dis3l2_C_term PF17877.1 KXS97560.1 - 0.055 13.8 0.0 0.18 12.2 0.0 1.9 1 0 0 1 1 1 0 DIS3-like exonuclease 2 C terminal AA_permease_2 PF13520.6 KXS97561.1 - 1.8e-40 139.1 48.3 2.3e-40 138.7 48.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXS97561.1 - 7e-15 54.6 42.2 9.4e-15 54.2 42.2 1.1 1 0 0 1 1 1 1 Amino acid permease ThrE PF06738.12 KXS97562.1 - 3.1e-71 239.6 8.1 7.5e-67 225.2 2.2 2.4 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KXS97562.1 - 1e-05 25.7 4.0 1e-05 25.7 4.0 4.1 4 0 0 4 4 4 2 Threonine/Serine exporter, ThrE NAD_kinase PF01513.21 KXS97563.1 - 3.8e-78 262.6 0.0 5.4e-78 262.1 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase MFS_1 PF07690.16 KXS97564.1 - 2.7e-20 72.6 17.6 3.1e-20 72.4 17.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS97564.1 - 1.5e-05 24.1 8.9 5.6e-05 22.2 5.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 KXS97564.1 - 0.0014 18.0 3.6 0.0017 17.8 3.6 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 KXS97564.1 - 0.17 10.2 3.4 0.18 10.2 3.4 1.0 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) Pmp3 PF01679.17 KXS97565.1 - 2.8e-24 85.0 8.6 3.2e-24 84.9 8.6 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Phage_holin_Dp1 PF16938.5 KXS97565.1 - 0.3 11.3 2.8 4.5 7.6 2.8 2.0 1 1 0 1 1 1 0 Putative phage holin Dp-1 Methyltransf_34 PF11312.8 KXS97566.1 - 1.5e-88 297.0 0.0 5.2e-88 295.2 0.0 1.7 2 0 0 2 2 2 1 Putative SAM-dependent methyltransferase Spermine_synth PF01564.17 KXS97566.1 - 1.1e-73 246.7 0.0 2e-73 245.8 0.0 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 KXS97566.1 - 9.1e-25 86.3 0.2 1.7e-24 85.4 0.2 1.5 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 KXS97566.1 - 2.3e-06 28.2 0.1 0.00044 20.9 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS97566.1 - 0.00033 21.3 0.1 0.038 14.7 0.0 3.2 3 0 0 3 3 3 1 Methyltransferase domain DUF43 PF01861.16 KXS97566.1 - 0.027 13.7 0.0 0.045 13.0 0.0 1.2 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain CheR PF01739.18 KXS97566.1 - 0.11 11.9 0.0 0.32 10.4 0.0 1.7 1 1 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_24 PF13578.6 KXS97566.1 - 0.14 13.2 0.0 0.85 10.7 0.0 2.3 3 0 0 3 3 3 0 Methyltransferase domain CDC14 PF08045.11 KXS97567.1 - 1.2e-121 405.3 3.5 1.3e-121 405.1 3.5 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component Myotub-related PF06602.14 KXS97568.1 - 4.2e-128 427.2 0.0 5.4e-128 426.8 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPn PF14671.6 KXS97569.1 - 3e-41 141.2 0.0 3.5e-39 134.5 0.0 2.5 2 1 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 KXS97569.1 - 1.4e-16 60.5 0.0 3.5e-16 59.2 0.0 1.6 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KXS97569.1 - 2e-05 24.3 0.1 5.4e-05 22.9 0.0 1.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 KXS97569.1 - 0.14 11.7 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family CsbD PF05532.12 KXS97572.1 - 1.3e-13 50.6 25.9 1.7e-06 27.8 0.8 3.2 2 1 1 3 3 3 3 CsbD-like COX6B PF02297.17 KXS97573.1 - 5.5e-18 65.0 8.1 1e-17 64.1 8.1 1.4 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CX9C PF16860.5 KXS97573.1 - 0.037 14.1 2.1 0.076 13.0 2.1 1.4 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, APOBEC_C PF05240.14 KXS97573.1 - 0.11 12.4 0.4 0.11 12.4 0.4 2.0 2 0 0 2 2 2 0 APOBEC-like C-terminal domain zf-C2H2 PF00096.26 KXS97574.1 - 0.021 15.3 3.7 1.1 9.8 0.1 3.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS97574.1 - 1.7 9.7 8.7 13 7.0 1.5 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KXS97575.1 - 0.021 15.3 3.7 1.1 9.8 0.1 3.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS97575.1 - 1.7 9.7 8.7 13 7.0 1.5 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KXS97576.1 - 0.026 15.0 3.7 1.2 9.7 0.1 3.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS97576.1 - 2.1 9.4 8.7 15 6.8 1.5 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger GSHPx PF00255.19 KXS97577.1 - 3.8e-39 132.6 0.0 5.1e-39 132.2 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 KXS97577.1 - 0.00064 19.6 0.0 0.0012 18.8 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family DUF4174 PF13778.6 KXS97577.1 - 0.0037 17.7 0.0 0.0072 16.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4174) Redoxin PF08534.10 KXS97577.1 - 0.065 13.0 0.1 0.11 12.2 0.1 1.5 2 0 0 2 2 2 0 Redoxin Zn_clus PF00172.18 KXS97578.1 - 0.2 11.8 9.7 0.35 11.0 9.7 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain CDC45 PF02724.14 KXS97579.1 - 0.14 10.4 11.0 0.27 9.5 11.0 1.4 1 0 0 1 1 1 0 CDC45-like protein SR-25 PF10500.9 KXS97579.1 - 1.7 8.2 20.8 5.1 6.6 3.2 4.0 4 0 0 4 4 4 0 Nuclear RNA-splicing-associated protein Sporozoite_P67 PF05642.11 KXS97579.1 - 4.6 5.2 9.5 7.5 4.5 9.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NOA36 PF06524.12 KXS97579.1 - 6.7 5.9 13.2 17 4.6 13.2 1.7 1 0 0 1 1 1 0 NOA36 protein AA_permease PF00324.21 KXS97585.1 - 9.7e-97 324.5 43.9 1.2e-96 324.2 43.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXS97585.1 - 3.4e-27 95.3 44.7 4.2e-27 95.0 44.7 1.1 1 0 0 1 1 1 1 Amino acid permease IBR PF01485.21 KXS97586.1 - 2.5e-09 37.2 46.9 0.00011 22.4 15.8 3.5 3 0 0 3 3 3 3 IBR domain, a half RING-finger domain DUF2158 PF09926.9 KXS97586.1 - 0.035 13.8 0.2 0.071 12.9 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized small protein (DUF2158) DUF3363 PF11843.8 KXS97587.1 - 0.018 14.0 0.1 0.021 13.8 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3363) adh_short PF00106.25 KXS97588.1 - 0.00057 19.4 0.0 0.00075 19.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS97588.1 - 0.0013 18.7 0.0 0.0018 18.2 0.0 1.2 1 0 0 1 1 1 1 KR domain ETS_PEA3_N PF04621.13 KXS97593.1 - 7.8e-05 22.7 5.2 0.00013 22.0 5.2 1.2 1 0 0 1 1 1 1 PEA3 subfamily ETS-domain transcription factor N terminal domain Rib_hydrolayse PF02267.17 KXS97594.1 - 0.084 12.3 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosyl cyclase GTP_EFTU PF00009.27 KXS97596.1 - 5e-06 26.2 0.0 1.8e-05 24.4 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF2195 PF09961.9 KXS97597.1 - 0.039 13.9 0.1 0.051 13.5 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2195) DUF1989 PF09347.10 KXS97597.1 - 0.089 12.4 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1989) AMP-binding PF00501.28 KXS97598.1 - 2.9e-67 227.1 0.0 4.5e-67 226.5 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KXS97598.1 - 1.5e-60 204.5 0.0 2.3e-60 204.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 KXS97598.1 - 2.2e-08 34.3 0.0 4.2e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 KXS97598.1 - 2.4e-08 33.7 0.0 1.8e-07 30.9 0.0 2.1 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXS97598.1 - 6.8e-07 28.6 0.0 1.4e-06 27.5 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 KXS97598.1 - 0.03 15.3 0.0 1 10.4 0.0 3.0 1 1 0 1 1 1 0 AMP-binding enzyme C-terminal domain dCMP_cyt_deam_1 PF00383.23 KXS97599.1 - 6.8e-07 29.1 0.0 0.002 17.9 0.0 2.9 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region TPR_2 PF07719.17 KXS97600.1 - 1.8e-33 111.9 36.9 0.0083 16.2 0.0 16.2 17 0 0 17 17 17 7 Tetratricopeptide repeat TPR_1 PF00515.28 KXS97600.1 - 3.1e-32 109.0 16.7 0.00046 19.9 0.0 13.2 13 0 0 13 13 12 6 Tetratricopeptide repeat TPR_16 PF13432.6 KXS97600.1 - 1.4e-30 105.6 39.1 1.2e-08 35.5 5.6 12.6 11 2 2 13 13 13 5 Tetratricopeptide repeat TPR_19 PF14559.6 KXS97600.1 - 4.8e-25 87.8 21.9 3.8e-06 27.3 4.0 11.7 10 2 1 12 12 11 5 Tetratricopeptide repeat TPR_14 PF13428.6 KXS97600.1 - 4.5e-22 76.9 38.2 0.0014 19.3 3.4 16.1 12 6 5 17 17 15 4 Tetratricopeptide repeat TPR_8 PF13181.6 KXS97600.1 - 3.6e-21 73.5 26.1 0.067 13.4 0.5 12.4 14 0 0 14 14 10 6 Tetratricopeptide repeat TPR_17 PF13431.6 KXS97600.1 - 3e-20 71.1 19.9 0.018 15.4 0.1 14.9 15 1 1 16 16 15 4 Tetratricopeptide repeat TPR_11 PF13414.6 KXS97600.1 - 1.4e-15 56.6 23.3 0.00032 20.3 0.0 11.5 11 3 1 13 13 11 3 TPR repeat TPR_7 PF13176.6 KXS97600.1 - 4.4e-14 51.4 19.4 0.019 15.0 0.0 11.4 13 0 0 13 13 10 4 Tetratricopeptide repeat TPR_12 PF13424.6 KXS97600.1 - 4.8e-14 52.4 49.9 0.0033 17.7 0.1 12.7 11 4 1 12 12 12 5 Tetratricopeptide repeat TPR_6 PF13174.6 KXS97600.1 - 4e-11 42.8 29.0 0.031 14.9 0.0 13.7 15 0 0 15 15 15 2 Tetratricopeptide repeat TPR_22 PF18833.1 KXS97600.1 - 5.3e-10 39.3 0.0 2e-09 37.4 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXS97600.1 - 1.3e-07 31.7 18.8 0.48 10.6 0.6 8.6 8 1 1 9 9 9 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KXS97600.1 - 1.3e-07 31.7 23.8 3.7e-05 23.9 1.2 8.0 8 2 2 10 10 10 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 KXS97600.1 - 5.9e-06 26.5 20.1 0.16 12.3 1.7 9.3 7 4 1 9 9 9 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KXS97600.1 - 0.0024 17.3 20.6 0.027 13.9 0.0 6.5 5 3 1 7 7 7 2 MalT-like TPR region Alkyl_sulf_dimr PF14863.6 KXS97600.1 - 0.003 18.0 2.1 0.02 15.4 1.0 3.2 2 1 0 2 2 2 1 Alkyl sulfatase dimerisation TPR_10 PF13374.6 KXS97600.1 - 0.011 15.6 21.4 3.1 7.8 0.1 9.0 9 0 0 9 9 9 0 Tetratricopeptide repeat DUF2225 PF09986.9 KXS97600.1 - 0.058 13.1 9.8 0.52 10.0 0.0 4.0 6 0 0 6 6 5 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_4 PF07721.14 KXS97600.1 - 0.11 13.1 24.9 0.59 10.9 0.1 8.9 11 0 0 11 11 7 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 KXS97600.1 - 0.14 12.1 8.6 2.1 8.2 1.2 4.4 5 0 0 5 5 5 0 Virulence factor membrane-bound polymerase, C-terminal TPR_3 PF07720.12 KXS97600.1 - 0.15 12.1 9.8 5.2 7.2 0.0 5.7 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_21 PF09976.9 KXS97600.1 - 0.17 11.6 16.5 0.011 15.5 3.1 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat-like domain ChAPs PF09295.10 KXS97600.1 - 2 7.3 8.3 21 4.0 0.0 4.7 6 0 0 6 6 6 0 ChAPs (Chs5p-Arf1p-binding proteins) Fis1_TPR_C PF14853.6 KXS97600.1 - 2.5 8.3 11.7 1.3e+02 2.8 0.1 7.2 9 1 1 10 10 10 0 Fis1 C-terminal tetratricopeptide repeat Sel1 PF08238.12 KXS97600.1 - 9.5 7.1 8.0 11 6.8 0.7 4.6 4 0 0 4 4 2 0 Sel1 repeat Zn_clus PF00172.18 KXS97601.1 - 4e-07 30.1 9.1 8.2e-07 29.1 9.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXS97601.1 - 8.6e-05 21.5 0.3 0.00012 21.1 0.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain OPT PF03169.15 KXS97602.1 - 1.4e-174 582.2 57.3 1.6e-174 582.0 57.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein YTH PF04146.15 KXS97603.1 - 2.3e-52 177.3 0.1 3.6e-52 176.6 0.1 1.3 1 0 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.22 KXS97603.1 - 5.4e-09 35.7 0.0 1.4e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PDCD2_C PF04194.13 KXS97605.1 - 3.2e-50 170.6 0.1 1.9e-47 161.6 0.0 2.4 2 0 0 2 2 2 2 Programmed cell death protein 2, C-terminal putative domain DUF3113 PF11310.8 KXS97605.1 - 0.2 11.6 0.0 0.4 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3113) Pol_alpha_B_N PF08418.10 KXS97605.1 - 6.6 6.6 11.4 2.2 8.2 8.2 1.7 1 1 1 2 2 2 0 DNA polymerase alpha subunit B N-terminal DUF4972 PF16342.5 KXS97606.1 - 0.016 14.9 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4972) Macoilin PF09726.9 KXS97606.1 - 0.035 12.7 1.3 0.041 12.5 1.3 1.0 1 0 0 1 1 1 0 Macoilin family IPP-2 PF04979.14 KXS97606.1 - 0.2 12.4 0.3 0.35 11.6 0.3 1.4 1 1 0 1 1 1 0 Protein phosphatase inhibitor 2 (IPP-2) Pkinase PF00069.25 KXS97607.1 - 2.3e-05 23.9 0.0 3.5e-05 23.3 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS97607.1 - 8.9e-05 21.9 0.0 0.00021 20.7 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase His_Phos_1 PF00300.22 KXS97608.1 - 5e-18 65.5 0.1 6.7e-18 65.1 0.1 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_28 PF13521.6 KXS97609.1 - 1.3e-26 93.8 0.0 1.5e-26 93.6 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXS97609.1 - 0.001 19.5 0.0 0.0014 19.1 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXS97609.1 - 0.0014 18.9 0.0 0.002 18.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KXS97609.1 - 0.009 15.1 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 KXS97609.1 - 0.011 16.3 0.0 0.011 16.3 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 KXS97609.1 - 0.021 14.6 0.0 0.044 13.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Thymidylate_kin PF02223.17 KXS97609.1 - 0.022 14.5 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 Thymidylate kinase MMR_HSR1 PF01926.23 KXS97609.1 - 0.023 14.8 0.0 0.027 14.5 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase dNK PF01712.19 KXS97609.1 - 0.028 14.3 0.0 0.068 13.0 0.0 1.6 1 1 0 1 1 1 0 Deoxynucleoside kinase AAA_18 PF13238.6 KXS97609.1 - 0.033 14.7 0.0 0.05 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KXS97609.1 - 0.041 13.6 0.0 0.059 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KXS97609.1 - 0.06 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Roc PF08477.13 KXS97609.1 - 0.062 13.5 0.0 0.11 12.7 0.0 1.5 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 KXS97609.1 - 0.13 11.8 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_ATPase PF09818.9 KXS97609.1 - 0.13 11.0 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class Septin PF00735.18 KXS97609.1 - 0.14 11.4 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Septin AAA-ATPase_like PF09820.9 KXS97609.1 - 0.15 11.5 0.0 0.2 11.0 0.0 1.1 1 0 0 1 1 1 0 Predicted AAA-ATPase AAA_33 PF13671.6 KXS97609.1 - 0.19 11.9 0.0 0.39 10.9 0.0 1.6 2 0 0 2 2 1 0 AAA domain Fungal_trans PF04082.18 KXS97611.1 - 1.8e-21 76.4 0.3 2.6e-21 75.8 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS97611.1 - 0.021 14.9 8.6 0.042 14.0 8.6 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain CDC45 PF02724.14 KXS97612.1 - 6.8 4.8 8.4 10 4.3 8.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KXS97612.1 - 9.6 4.3 13.4 14 3.7 13.4 1.1 1 0 0 1 1 1 0 Nop14-like family COG7 PF10191.9 KXS97613.1 - 0.17 10.1 0.0 0.17 10.1 0.0 1.1 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) Abhydrolase_4 PF08386.10 KXS97614.1 - 5.6e-18 64.9 0.0 1.9e-17 63.3 0.0 1.8 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.20 KXS97614.1 - 3.4e-14 53.1 0.0 8.6e-12 45.2 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold UL42 PF17638.2 KXS97614.1 - 0.034 14.1 0.1 0.065 13.2 0.1 1.4 1 0 0 1 1 1 0 HCMV UL42 TAL_FSA PF00923.19 KXS97614.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Transaldolase/Fructose-6-phosphate aldolase Methyltransf_25 PF13649.6 KXS97615.1 - 2.1e-15 57.2 0.0 3e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS97615.1 - 6.8e-14 52.3 0.0 9.8e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS97615.1 - 5e-08 33.6 0.0 7.3e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXS97615.1 - 2.4e-07 30.7 0.0 3.4e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS97615.1 - 1.8e-06 27.9 0.0 2.3e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KXS97615.1 - 2.8e-06 27.2 0.0 4.6e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 KXS97615.1 - 7e-06 25.5 0.0 9.5e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 KXS97615.1 - 7.2e-05 22.2 0.0 0.00011 21.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family RrnaAD PF00398.20 KXS97615.1 - 0.0031 16.6 0.0 0.0043 16.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PrmA PF06325.13 KXS97615.1 - 0.0037 16.7 0.0 0.0051 16.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_PK PF05891.12 KXS97615.1 - 0.0053 16.3 0.0 0.0076 15.8 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase MetW PF07021.12 KXS97615.1 - 0.0063 16.1 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW N2227 PF07942.12 KXS97615.1 - 0.22 10.7 0.0 3.1 6.9 0.0 2.0 2 0 0 2 2 2 0 N2227-like protein Toxin_2 PF00451.19 KXS97616.1 - 5.4 7.4 7.2 0.25 11.7 1.1 2.0 2 0 0 2 2 2 0 Scorpion short toxin, BmKK2 Hydrophobin_2 PF06766.11 KXS97617.1 - 1.1e-16 60.5 11.9 1.1e-16 60.5 11.9 2.0 2 0 0 2 2 2 1 Fungal hydrophobin GRP PF07172.11 KXS97617.1 - 0.0015 19.2 9.5 0.0022 18.7 9.5 1.2 1 0 0 1 1 1 1 Glycine rich protein family zf-RING_2 PF13639.6 KXS97618.1 - 1.4e-10 41.3 6.0 2.2e-10 40.7 6.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXS97618.1 - 4.6e-08 32.8 5.5 7.1e-08 32.2 5.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXS97618.1 - 6.9e-08 32.2 2.8 9.7e-08 31.8 2.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS97618.1 - 7.3e-08 32.1 4.9 1.1e-07 31.6 4.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXS97618.1 - 9.6e-06 25.8 4.9 2.5e-05 24.5 4.9 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KXS97618.1 - 6.5e-05 22.7 3.9 0.0001 22.1 3.9 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KXS97618.1 - 0.0012 18.8 3.2 0.0024 17.9 3.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 KXS97618.1 - 0.0092 15.7 2.0 0.019 14.7 2.0 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 KXS97618.1 - 0.016 15.2 3.1 0.027 14.4 3.1 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Zn_ribbon_17 PF17120.5 KXS97618.1 - 0.11 12.2 2.4 0.18 11.5 2.4 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type CTU2 PF10288.9 KXS97618.1 - 0.25 11.6 1.4 1.1 9.5 1.4 1.9 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 MFS_1 PF07690.16 KXS97619.1 - 1.8e-36 125.8 26.7 2.3e-36 125.4 26.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily CbtB PF09489.10 KXS97619.1 - 0.2 11.8 2.8 8.1 6.6 0.2 3.3 3 0 0 3 3 3 0 Probable cobalt transporter subunit (CbtB) MFS_1 PF07690.16 KXS97620.1 - 1.8e-36 125.8 26.7 2.3e-36 125.4 26.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily CbtB PF09489.10 KXS97620.1 - 0.2 11.8 2.8 8.1 6.6 0.2 3.3 3 0 0 3 3 3 0 Probable cobalt transporter subunit (CbtB) Cnn_1N PF07989.11 KXS97621.1 - 7.5e-21 74.1 6.7 7.5e-21 74.1 6.7 13.1 9 3 3 12 12 12 1 Centrosomin N-terminal motif 1 Mto2_bdg PF12808.7 KXS97621.1 - 1.5e-16 60.4 18.8 1.5e-16 60.4 18.8 9.8 9 2 1 11 11 11 2 Micro-tubular organiser Mto1 C-term Mto2-binding region RdRP PF05183.12 KXS97622.1 - 1.1e-110 371.0 0.0 1.8e-110 370.3 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase AAA_12 PF13087.6 KXS97622.1 - 5.2e-45 153.5 0.0 1.1e-44 152.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KXS97622.1 - 5.7e-41 141.0 0.4 2e-21 77.0 0.3 2.4 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.6 KXS97622.1 - 8.8e-12 45.6 0.1 7e-11 42.7 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KXS97622.1 - 1.4e-11 44.5 0.1 4.8e-10 39.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 KXS97622.1 - 3.4e-06 27.2 0.0 9.6e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD_C_2 PF13538.6 KXS97622.1 - 3.9e-05 23.4 0.0 0.00011 22.0 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 KXS97622.1 - 0.00011 22.0 0.0 1.5 8.5 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 KXS97622.1 - 0.0003 20.4 0.1 0.012 15.1 0.0 2.7 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 KXS97622.1 - 0.00054 19.9 0.0 0.0023 17.8 0.0 2.1 1 1 0 1 1 1 1 Helicase PhoH PF02562.16 KXS97622.1 - 0.00069 19.1 0.0 0.0026 17.2 0.0 1.9 1 1 0 1 1 1 1 PhoH-like protein AAA PF00004.29 KXS97622.1 - 0.0068 16.8 0.0 0.022 15.2 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FANCF PF11107.8 KXS97622.1 - 0.0071 15.6 0.1 0.017 14.4 0.1 1.6 1 0 0 1 1 1 1 Fanconi anemia group F protein (FANCF) AAA_22 PF13401.6 KXS97622.1 - 0.0084 16.4 0.1 0.056 13.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 KXS97622.1 - 0.011 15.5 0.0 0.039 13.7 0.0 1.9 2 0 0 2 2 2 0 DEAD/DEAH box helicase Mg_chelatase PF01078.21 KXS97622.1 - 0.011 15.1 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Bac_DnaA PF00308.18 KXS97622.1 - 0.044 13.6 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_16 PF13191.6 KXS97622.1 - 0.054 13.9 0.2 0.28 11.5 0.0 2.3 3 0 0 3 3 1 0 AAA ATPase domain GARP PF16731.5 KXS97622.1 - 0.088 12.5 0.1 0.19 11.4 0.1 1.5 1 0 0 1 1 1 0 Glutamic acid/alanine-rich protein of Trypanosoma AAA_24 PF13479.6 KXS97622.1 - 0.17 11.6 0.0 0.75 9.5 0.0 2.1 3 0 0 3 3 2 0 AAA domain HIT PF01230.23 KXS97623.1 - 5.5e-21 75.1 0.0 7.7e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KXS97623.1 - 6.7e-13 49.1 0.0 9.9e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KXS97623.1 - 0.00053 19.9 0.0 0.00077 19.3 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 RdRP PF05183.12 KXS97624.1 - 7.9e-111 371.5 0.0 1.2e-110 370.9 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase AAA_11 PF13086.6 KXS97624.1 - 2.2e-15 57.2 0.0 4e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXS97624.1 - 1.1e-08 35.5 0.0 2.8e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXS97624.1 - 1.1e-06 28.6 0.0 2.2e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KXS97624.1 - 2.6e-05 24.3 0.0 7e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 KXS97624.1 - 0.0023 17.8 0.0 0.0076 16.1 0.0 1.9 2 0 0 2 2 2 1 Helicase PhoH PF02562.16 KXS97624.1 - 0.0027 17.2 0.0 0.0055 16.2 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein AAA PF00004.29 KXS97624.1 - 0.0078 16.6 0.0 0.019 15.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KXS97624.1 - 0.0088 15.4 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DEAD PF00270.29 KXS97624.1 - 0.011 15.6 0.0 0.043 13.6 0.0 2.0 2 0 0 2 2 2 0 DEAD/DEAH box helicase UvrD-helicase PF00580.21 KXS97624.1 - 0.017 14.7 0.0 0.061 12.8 0.0 1.9 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 KXS97624.1 - 0.02 15.2 0.0 0.076 13.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.18 KXS97624.1 - 0.035 14.0 0.0 0.081 12.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_16 PF13191.6 KXS97624.1 - 0.048 14.1 0.0 0.31 11.4 0.0 2.3 3 0 0 3 3 3 0 AAA ATPase domain GARP PF16731.5 KXS97624.1 - 0.066 12.9 0.1 0.15 11.7 0.1 1.6 1 0 0 1 1 1 0 Glutamic acid/alanine-rich protein of Trypanosoma T2SSE PF00437.20 KXS97624.1 - 0.14 11.2 0.0 0.29 10.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Rad17 PF03215.15 KXS97624.1 - 0.14 12.0 0.0 0.4 10.6 0.0 1.7 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_24 PF13479.6 KXS97624.1 - 0.19 11.5 0.0 0.69 9.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain HIT PF01230.23 KXS97625.1 - 5.5e-21 75.1 0.0 7.7e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KXS97625.1 - 6.7e-13 49.1 0.0 9.9e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KXS97625.1 - 0.00053 19.9 0.0 0.00077 19.3 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 RdRP PF05183.12 KXS97626.1 - 1.1e-110 371.0 0.0 1.8e-110 370.3 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase AAA_12 PF13087.6 KXS97626.1 - 5.2e-45 153.5 0.0 1.1e-44 152.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KXS97626.1 - 5.7e-41 141.0 0.4 2e-21 77.0 0.3 2.4 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.6 KXS97626.1 - 8.8e-12 45.6 0.1 7e-11 42.7 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KXS97626.1 - 1.4e-11 44.5 0.1 4.8e-10 39.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 KXS97626.1 - 3.4e-06 27.2 0.0 9.6e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD_C_2 PF13538.6 KXS97626.1 - 3.9e-05 23.4 0.0 0.00011 22.0 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 KXS97626.1 - 0.00011 22.0 0.0 1.5 8.5 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 KXS97626.1 - 0.0003 20.4 0.1 0.012 15.1 0.0 2.7 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 KXS97626.1 - 0.00054 19.9 0.0 0.0023 17.8 0.0 2.1 1 1 0 1 1 1 1 Helicase PhoH PF02562.16 KXS97626.1 - 0.00069 19.1 0.0 0.0026 17.2 0.0 1.9 1 1 0 1 1 1 1 PhoH-like protein AAA PF00004.29 KXS97626.1 - 0.0068 16.8 0.0 0.022 15.2 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FANCF PF11107.8 KXS97626.1 - 0.0071 15.6 0.1 0.017 14.4 0.1 1.6 1 0 0 1 1 1 1 Fanconi anemia group F protein (FANCF) AAA_22 PF13401.6 KXS97626.1 - 0.0084 16.4 0.1 0.056 13.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 KXS97626.1 - 0.011 15.5 0.0 0.039 13.7 0.0 1.9 2 0 0 2 2 2 0 DEAD/DEAH box helicase Mg_chelatase PF01078.21 KXS97626.1 - 0.011 15.1 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Bac_DnaA PF00308.18 KXS97626.1 - 0.044 13.6 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_16 PF13191.6 KXS97626.1 - 0.054 13.9 0.2 0.28 11.5 0.0 2.3 3 0 0 3 3 1 0 AAA ATPase domain GARP PF16731.5 KXS97626.1 - 0.088 12.5 0.1 0.19 11.4 0.1 1.5 1 0 0 1 1 1 0 Glutamic acid/alanine-rich protein of Trypanosoma AAA_24 PF13479.6 KXS97626.1 - 0.17 11.6 0.0 0.75 9.5 0.0 2.1 3 0 0 3 3 2 0 AAA domain HIT PF01230.23 KXS97627.1 - 5.5e-21 75.1 0.0 7.7e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KXS97627.1 - 6.7e-13 49.1 0.0 9.9e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KXS97627.1 - 0.00053 19.9 0.0 0.00077 19.3 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 HIT PF01230.23 KXS97628.1 - 5.5e-21 75.1 0.0 7.7e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KXS97628.1 - 6.7e-13 49.1 0.0 9.9e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KXS97628.1 - 0.00053 19.9 0.0 0.00077 19.3 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 RdRP PF05183.12 KXS97629.1 - 7.9e-111 371.5 0.0 1.2e-110 370.9 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase AAA_11 PF13086.6 KXS97629.1 - 2.2e-15 57.2 0.0 4e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXS97629.1 - 1.1e-08 35.5 0.0 2.8e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXS97629.1 - 1.1e-06 28.6 0.0 2.2e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KXS97629.1 - 2.6e-05 24.3 0.0 7e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 KXS97629.1 - 0.0023 17.8 0.0 0.0076 16.1 0.0 1.9 2 0 0 2 2 2 1 Helicase PhoH PF02562.16 KXS97629.1 - 0.0027 17.2 0.0 0.0055 16.2 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein AAA PF00004.29 KXS97629.1 - 0.0078 16.6 0.0 0.019 15.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KXS97629.1 - 0.0088 15.4 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DEAD PF00270.29 KXS97629.1 - 0.011 15.6 0.0 0.043 13.6 0.0 2.0 2 0 0 2 2 2 0 DEAD/DEAH box helicase UvrD-helicase PF00580.21 KXS97629.1 - 0.017 14.7 0.0 0.061 12.8 0.0 1.9 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 KXS97629.1 - 0.02 15.2 0.0 0.076 13.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.18 KXS97629.1 - 0.035 14.0 0.0 0.081 12.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_16 PF13191.6 KXS97629.1 - 0.048 14.1 0.0 0.31 11.4 0.0 2.3 3 0 0 3 3 3 0 AAA ATPase domain GARP PF16731.5 KXS97629.1 - 0.066 12.9 0.1 0.15 11.7 0.1 1.6 1 0 0 1 1 1 0 Glutamic acid/alanine-rich protein of Trypanosoma T2SSE PF00437.20 KXS97629.1 - 0.14 11.2 0.0 0.29 10.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Rad17 PF03215.15 KXS97629.1 - 0.14 12.0 0.0 0.4 10.6 0.0 1.7 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_24 PF13479.6 KXS97629.1 - 0.19 11.5 0.0 0.69 9.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain CSN8_PSD8_EIF3K PF10075.9 KXS97630.1 - 4.8e-38 130.4 0.0 6.7e-38 129.9 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family Abhydrolase_1 PF00561.20 KXS97633.1 - 4.7e-25 88.7 0.3 2.8e-19 69.8 0.1 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXS97633.1 - 4.4e-22 78.5 0.9 4e-21 75.4 0.9 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXS97633.1 - 2.3e-15 57.8 0.0 3.6e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 KXS97633.1 - 1.8e-09 36.7 0.0 2.9e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Ndr family DLH PF01738.18 KXS97633.1 - 6.2e-09 35.7 0.1 0.00025 20.7 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KXS97633.1 - 2.2e-07 30.6 0.1 0.0067 15.9 0.0 2.2 1 1 1 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.20 KXS97633.1 - 3.5e-07 30.1 0.0 6.8e-07 29.2 0.0 1.5 1 1 1 2 2 2 1 Putative esterase BAAT_C PF08840.11 KXS97633.1 - 6.1e-07 29.6 0.1 1.2e-06 28.6 0.1 1.4 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 KXS97633.1 - 1.1e-05 25.3 0.0 0.022 14.5 0.0 2.9 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Ser_hydrolase PF06821.13 KXS97633.1 - 7e-05 22.8 0.0 0.0029 17.5 0.0 2.2 1 1 1 2 2 2 1 Serine hydrolase Abhydrolase_4 PF08386.10 KXS97633.1 - 7e-05 22.9 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_5 PF12695.7 KXS97633.1 - 0.00022 21.0 0.1 0.00078 19.2 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family AXE1 PF05448.12 KXS97633.1 - 0.00025 19.8 0.1 0.39 9.4 0.1 2.4 3 0 0 3 3 3 2 Acetyl xylan esterase (AXE1) Thioesterase PF00975.20 KXS97633.1 - 0.00037 20.7 0.0 0.00053 20.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain LIDHydrolase PF10230.9 KXS97633.1 - 0.0018 17.9 0.1 0.034 13.7 0.0 2.1 1 1 0 2 2 2 1 Lipid-droplet associated hydrolase PGAP1 PF07819.13 KXS97633.1 - 0.0028 17.4 0.0 0.0045 16.7 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Esterase_phd PF10503.9 KXS97633.1 - 0.0031 17.0 0.2 0.0044 16.5 0.2 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase DUF676 PF05057.14 KXS97633.1 - 0.013 15.0 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_3 PF07859.13 KXS97633.1 - 0.014 15.3 0.4 0.022 14.6 0.4 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF1057 PF06342.12 KXS97633.1 - 0.018 14.1 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Lipase_3 PF01764.25 KXS97633.1 - 0.032 14.1 0.0 0.052 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Chlorophyllase2 PF12740.7 KXS97633.1 - 0.041 12.8 0.3 0.084 11.8 0.3 1.6 1 1 0 1 1 1 0 Chlorophyllase enzyme Chlorophyllase PF07224.11 KXS97633.1 - 0.095 11.7 0.4 0.16 10.9 0.4 1.4 1 1 0 1 1 1 0 Chlorophyllase DUF915 PF06028.11 KXS97633.1 - 0.1 11.9 0.1 1.7 7.9 0.0 2.5 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) DUF2974 PF11187.8 KXS97633.1 - 0.14 11.7 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Tannase PF07519.11 KXS97633.1 - 0.16 10.8 0.0 0.25 10.2 0.0 1.3 1 0 0 1 1 1 0 Tannase and feruloyl esterase Glyco_hydro_1 PF00232.18 KXS97636.1 - 2e-116 389.1 3.4 2.8e-116 388.6 3.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_10 PF00331.20 KXS97636.1 - 0.095 11.8 0.1 12 5.0 0.0 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase family 10 Phytoreo_S7 PF07236.11 KXS97654.1 - 0.4 9.0 1.5 0.45 8.8 0.2 1.6 2 0 0 2 2 2 0 Phytoreovirus S7 protein MPP6 PF10175.9 KXS97660.1 - 0.017 15.6 0.1 0.065 13.7 0.0 1.8 2 0 0 2 2 2 0 M-phase phosphoprotein 6 zf-RING_2 PF13639.6 KXS97661.1 - 1.4e-05 25.3 1.7 1.4e-05 25.3 1.7 2.9 3 0 0 3 3 3 1 Ring finger domain Prok-RING_1 PF14446.6 KXS97661.1 - 0.0028 17.5 1.9 0.0028 17.5 1.9 3.1 3 0 0 3 3 3 1 Prokaryotic RING finger family 1 zf-HC5HC2H PF13771.6 KXS97661.1 - 0.02 15.2 0.6 0.05 13.9 0.6 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain FANCL_C PF11793.8 KXS97661.1 - 0.026 14.7 0.4 0.026 14.7 0.4 2.3 2 0 0 2 2 2 0 FANCL C-terminal domain zf-RING_11 PF17123.5 KXS97661.1 - 0.33 10.7 3.0 0.73 9.6 3.0 1.7 1 0 0 1 1 1 0 RING-like zinc finger PHD PF00628.29 KXS97661.1 - 7.9 6.5 14.6 0.036 14.0 4.2 2.5 3 1 0 3 3 3 0 PHD-finger Cys_rich_CPXG PF14255.6 KXS97661.1 - 10 6.1 7.5 2.9 7.9 0.2 3.2 4 0 0 4 4 4 0 Cysteine-rich CPXCG TMF_DNA_bd PF12329.8 KXS97665.1 - 0.021 14.8 6.8 0.021 14.8 6.8 2.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Shugoshin_N PF07558.11 KXS97665.1 - 0.036 13.9 0.5 0.036 13.9 0.5 3.4 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region SSP160 PF06933.11 KXS97665.1 - 0.29 9.3 4.3 0.41 8.8 4.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 CENP-F_leu_zip PF10473.9 KXS97665.1 - 0.38 10.8 17.9 2.4 8.2 14.9 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TSC22 PF01166.18 KXS97665.1 - 4.9 7.5 14.8 13 6.2 2.5 3.9 2 1 3 5 5 5 0 TSC-22/dip/bun family GAS PF13851.6 KXS97665.1 - 5 6.4 19.5 7.9 5.8 19.5 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Macoilin PF09726.9 KXS97665.1 - 6.4 5.2 17.3 13 4.2 16.8 1.6 1 1 1 2 2 2 0 Macoilin family Pentapeptide_2 PF01469.18 KXS97667.1 - 2.4e-13 49.7 10.3 3e-08 33.4 4.4 2.5 1 1 1 2 2 2 2 Pentapeptide repeats (8 copies) CDC45 PF02724.14 KXS97669.1 - 0.036 12.4 0.5 0.045 12.0 0.5 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF4906 PF16249.5 KXS97670.1 - 0.049 13.5 0.0 0.057 13.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4906) S-l_SbsC_C PF18316.1 KXS97670.1 - 0.13 12.7 0.1 0.19 12.3 0.1 1.3 1 0 0 1 1 1 0 S-layer protein SbsC C-terminal domain DUF3552 PF12072.8 KXS97682.1 - 0.0041 16.6 46.8 0.053 12.9 27.3 3.1 1 1 2 3 3 3 3 Domain of unknown function (DUF3552) ELK PF03789.13 KXS97682.1 - 0.018 15.1 0.6 0.058 13.5 0.6 1.9 1 0 0 1 1 1 0 ELK domain Jnk-SapK_ap_N PF09744.9 KXS97682.1 - 3.6 7.8 40.4 0.033 14.4 19.2 2.6 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF4472 PF14739.6 KXS97682.1 - 8.1 7.2 31.3 5.9 7.7 6.4 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) Ustilago_mating PF05722.12 KXS97683.1 - 1.6 8.2 5.6 2.1 7.8 5.6 1.1 1 0 0 1 1 1 0 Ustilago B locus mating-type protein DUF2946 PF11162.8 KXS97683.1 - 1.6 9.4 8.3 0.15 12.7 3.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) Pex14_N PF04695.13 KXS97692.1 - 1.9e-05 25.4 0.4 3.2e-05 24.6 0.4 1.3 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region LRR19-TM PF15176.6 KXS97692.1 - 0.068 13.2 0.3 0.23 11.5 0.0 1.9 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain Ndc1_Nup PF09531.10 KXS97692.1 - 0.084 11.6 0.8 0.086 11.5 0.8 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup EVI2A PF05399.11 KXS97692.1 - 0.12 12.0 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) 7TM_GPCR_Srd PF10317.9 KXS97694.1 - 0.11 11.7 0.3 0.14 11.3 0.3 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd RACo_linker PF17650.1 KXS97696.1 - 0.16 11.9 1.1 5.4 7.0 0.5 2.4 2 0 0 2 2 2 0 RACo linker region PRIMA1 PF16101.5 KXS97697.1 - 9.7e-05 22.4 1.7 0.00015 21.8 1.7 1.3 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 DUF4907 PF16250.5 KXS97697.1 - 0.066 13.1 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4907) CAP_N PF01213.19 KXS97697.1 - 0.69 9.3 3.4 0.95 8.9 3.4 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Borrelia_P83 PF05262.11 KXS97698.1 - 0.00047 18.8 33.6 0.00066 18.3 33.6 1.1 1 0 0 1 1 1 1 Borrelia P83/100 protein V_ATPase_I PF01496.19 KXS97698.1 - 0.29 9.0 14.3 0.43 8.4 14.3 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family WYL_2 PF10902.8 KXS97699.1 - 0.04 14.3 0.1 0.059 13.7 0.1 1.5 1 1 0 1 1 1 0 WYL_2, Sm-like SH3 beta-barrel fold Methyltransf_9 PF08003.11 KXS97699.1 - 0.083 11.8 0.2 0.083 11.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Aldose_epim PF01263.20 KXS97705.1 - 2.1e-62 211.1 0.0 2.7e-62 210.8 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Aldose_epim PF01263.20 KXS97706.1 - 2.5e-62 210.9 0.0 3.2e-62 210.6 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Cpn60_TCP1 PF00118.24 KXS97707.1 - 1.5e-164 548.3 0.3 1.7e-164 548.1 0.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FAD_binding_4 PF01565.23 KXS97708.1 - 7.5e-23 80.8 1.1 1.4e-22 80.0 1.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXS97708.1 - 2.7e-12 46.6 0.0 7.8e-12 45.1 0.0 1.8 2 0 0 2 2 2 1 Berberine and berberine like ubiquitin PF00240.23 KXS97710.1 - 1.1e-26 92.3 0.6 5.8e-23 80.4 0.0 2.7 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 KXS97710.1 - 9.6e-13 47.8 0.2 1.3e-10 41.0 0.0 2.9 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 KXS97710.1 - 0.15 12.0 0.0 0.39 10.7 0.0 1.7 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Asp-B-Hydro_N PF05279.11 KXS97710.1 - 0.51 10.4 15.9 0.88 9.6 15.9 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF2407 PF10302.9 KXS97710.1 - 0.52 10.9 0.1 0.52 10.9 0.1 2.9 2 1 0 2 2 2 0 DUF2407 ubiquitin-like domain F-box PF00646.33 KXS97711.1 - 2.9e-07 30.2 0.3 6.4e-07 29.1 0.3 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXS97711.1 - 0.0064 16.4 0.6 0.014 15.3 0.6 1.5 1 0 0 1 1 1 1 F-box-like Piwi PF02171.17 KXS97712.1 - 3.2e-75 253.2 0.0 4.8e-75 252.6 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KXS97712.1 - 4.1e-18 66.3 0.0 8.9e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KXS97712.1 - 1.4e-16 59.8 2.1 1.7e-16 59.6 0.1 2.3 3 0 0 3 3 3 1 Argonaute linker 1 domain PAZ PF02170.22 KXS97712.1 - 2.5e-16 59.7 0.8 4.7e-16 58.8 0.8 1.4 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 KXS97712.1 - 1.3e-11 44.6 0.0 2.8e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 KXS97712.1 - 5.8e-08 32.9 0.0 2.1e-07 31.1 0.0 1.9 1 0 0 1 1 1 1 Mid domain of argonaute Rhomboid PF01694.22 KXS97714.1 - 8.4e-13 48.6 9.1 1.4e-12 47.8 9.1 1.3 1 0 0 1 1 1 1 Rhomboid family L6_membrane PF05805.12 KXS97714.1 - 0.055 13.0 0.2 0.11 12.0 0.2 1.5 1 0 0 1 1 1 0 L6 membrane protein Pyridoxal_deC PF00282.19 KXS97715.1 - 5.4e-29 101.1 0.0 9.7e-29 100.2 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.17 KXS97715.1 - 0.00079 18.8 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family SepSecS PF05889.13 KXS97715.1 - 0.0087 14.8 0.0 0.014 14.1 0.0 1.2 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Beta_elim_lyase PF01212.21 KXS97715.1 - 0.011 15.1 0.1 0.02 14.2 0.1 1.4 1 1 0 1 1 1 0 Beta-eliminating lyase Aminotran_5 PF00266.19 KXS97715.1 - 0.02 13.9 0.0 0.037 13.0 0.0 1.6 1 1 0 1 1 1 0 Aminotransferase class-V Pyridoxal_deC PF00282.19 KXS97716.1 - 5.4e-29 101.1 0.0 9.7e-29 100.2 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.17 KXS97716.1 - 0.00079 18.8 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family SepSecS PF05889.13 KXS97716.1 - 0.0087 14.8 0.0 0.014 14.1 0.0 1.2 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Beta_elim_lyase PF01212.21 KXS97716.1 - 0.011 15.1 0.1 0.02 14.2 0.1 1.4 1 1 0 1 1 1 0 Beta-eliminating lyase Aminotran_5 PF00266.19 KXS97716.1 - 0.02 13.9 0.0 0.037 13.0 0.0 1.6 1 1 0 1 1 1 0 Aminotransferase class-V Pyridoxal_deC PF00282.19 KXS97717.1 - 7.2e-29 100.6 0.0 1.3e-28 99.8 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.17 KXS97717.1 - 0.00092 18.6 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family SepSecS PF05889.13 KXS97717.1 - 0.01 14.6 0.0 0.017 13.9 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Beta_elim_lyase PF01212.21 KXS97717.1 - 0.012 14.9 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_5 PF00266.19 KXS97717.1 - 0.024 13.6 0.0 0.046 12.7 0.0 1.6 1 1 0 1 1 1 0 Aminotransferase class-V Aminotran_1_2 PF00155.21 KXS97717.1 - 0.1 11.8 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II HSP9_HSP12 PF04119.12 KXS97718.1 - 3.5e-22 78.5 10.2 3.5e-22 78.5 10.2 1.9 2 0 0 2 2 2 1 Heat shock protein 9/12 ADD_ATRX PF17981.1 KXS97719.1 - 0.15 12.0 0.7 0.38 10.7 0.0 2.0 2 0 0 2 2 2 0 Cysteine Rich ADD domain AMMECR1 PF01871.17 KXS97720.1 - 1.7e-39 135.1 0.0 3.6e-39 134.1 0.0 1.6 1 1 0 1 1 1 1 AMMECR1 DUF4599 PF15371.6 KXS97720.1 - 0.2 12.2 4.1 0.26 11.9 1.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4599) Apt1 PF10351.9 KXS97720.1 - 0.32 9.8 3.8 0.38 9.6 3.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4592 PF15262.6 KXS97720.1 - 1.3 9.7 10.4 2.5 8.8 10.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4592) Peroxidase_2 PF01328.17 KXS97724.1 - 1.7e-37 129.8 0.1 4.7e-26 92.5 0.0 2.1 2 0 0 2 2 2 2 Peroxidase, family 2 Glyco_hydro_18 PF00704.28 KXS97727.1 - 2e-89 300.4 0.3 2.4e-89 300.2 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.28 KXS97728.1 - 1.8e-89 300.6 0.3 2.1e-89 300.4 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Gaa1 PF04114.14 KXS97729.1 - 2.4e-161 538.2 4.1 3.5e-161 537.6 4.1 1.2 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component Suf PF05843.14 KXS97730.1 - 3e-71 240.8 3.0 1.3e-66 225.6 0.0 4.0 4 0 0 4 4 4 2 Suppressor of forked protein (Suf) TPR_19 PF14559.6 KXS97730.1 - 2.5e-07 31.1 0.0 0.076 13.5 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXS97730.1 - 1.1e-05 25.9 0.4 0.18 12.7 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 KXS97730.1 - 0.013 14.7 0.2 5.3 6.2 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat NRDE-2 PF08424.10 KXS97730.1 - 0.014 14.5 2.3 3 6.9 0.2 2.7 2 1 0 2 2 2 0 NRDE-2, necessary for RNA interference SOG2 PF10428.9 KXS97730.1 - 0.47 9.6 12.9 0.86 8.7 12.9 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein UNC-50 PF05216.13 KXS97731.1 - 2.9e-79 265.7 8.2 3.2e-79 265.6 8.2 1.0 1 0 0 1 1 1 1 UNC-50 family DPM2 PF07297.12 KXS97731.1 - 3.5 8.0 11.0 0.11 12.8 3.2 2.5 2 1 1 3 3 3 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Zn_clus PF00172.18 KXS97732.1 - 9.7e-09 35.2 13.6 2.1e-08 34.1 13.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KXS97738.1 - 1.3e-10 41.2 11.8 2.5e-10 40.3 11.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXS97738.1 - 6e-07 28.8 0.0 1.7e-06 27.3 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain SYS1 PF09801.9 KXS97738.1 - 0.081 13.1 0.4 0.21 11.7 0.4 1.6 1 0 0 1 1 1 0 Integral membrane protein S linking to the trans Golgi network Zn_clus PF00172.18 KXS97739.1 - 1.3e-10 41.2 11.8 2.5e-10 40.3 11.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXS97739.1 - 6e-07 28.8 0.0 1.7e-06 27.3 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain SYS1 PF09801.9 KXS97739.1 - 0.081 13.1 0.4 0.21 11.7 0.4 1.6 1 0 0 1 1 1 0 Integral membrane protein S linking to the trans Golgi network Zn_clus PF00172.18 KXS97740.1 - 1.4e-10 41.1 11.8 2.5e-10 40.3 11.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXS97740.1 - 6.2e-07 28.7 0.0 1.8e-06 27.2 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain SYS1 PF09801.9 KXS97740.1 - 0.081 13.1 0.4 0.21 11.7 0.4 1.6 1 0 0 1 1 1 0 Integral membrane protein S linking to the trans Golgi network Sld5 PF05916.11 KXS97741.1 - 9.9e-14 51.7 0.0 1.3e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein Glyco_hydro_3_C PF01915.22 KXS97742.1 - 1.4e-63 214.5 0.0 2.3e-63 213.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXS97742.1 - 1.2e-48 166.1 0.0 2.3e-48 165.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXS97742.1 - 1e-24 86.4 0.3 3.8e-24 84.6 0.3 2.0 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.12 KXS97742.1 - 4.1e-18 65.6 0.0 7e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 PA14 domain DUF883 PF05957.13 KXS97743.1 - 0.15 12.6 0.8 0.46 11.1 0.8 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) MFS_1 PF07690.16 KXS97744.1 - 3.4e-27 95.3 50.9 6.7e-22 77.9 23.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KXS97744.1 - 3.5e-05 23.3 16.9 4.9e-05 22.8 16.9 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_1 PF07690.16 KXS97745.1 - 3.4e-27 95.3 50.9 6.7e-22 77.9 23.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KXS97745.1 - 3.5e-05 23.3 16.9 4.9e-05 22.8 16.9 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Glyco_hydro2_C5 PF18565.1 KXS97746.1 - 2.6e-26 91.5 0.1 2.9e-26 91.3 0.1 1.0 1 0 0 1 1 1 1 Glycoside hydrolase family 2 C-terminal domain 5 Invasin_D3 PF09134.10 KXS97746.1 - 0.002 18.4 1.9 0.012 15.9 0.3 2.0 2 0 0 2 2 2 1 Invasin, domain 3 LRR_4 PF12799.7 KXS97747.1 - 1.3e-40 136.7 13.2 1.1e-08 35.3 1.0 6.3 5 1 1 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS97747.1 - 1.7e-22 79.0 18.4 6e-07 29.1 1.0 6.1 2 1 5 7 7 7 6 Leucine rich repeat LRR_9 PF14580.6 KXS97747.1 - 6.1e-15 55.2 10.2 6.9e-07 28.9 0.6 4.0 1 1 2 4 4 4 2 Leucine-rich repeat LRR_1 PF00560.33 KXS97747.1 - 0.00019 21.6 20.1 7.8 7.5 0.1 9.1 9 2 0 9 9 9 1 Leucine Rich Repeat LRR_6 PF13516.6 KXS97747.1 - 0.045 13.8 19.9 3.2 8.0 0.1 7.9 8 1 1 9 9 9 0 Leucine Rich repeat SE PF08491.10 KXS97748.1 - 3.5e-104 347.7 0.0 4.8e-104 347.3 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 KXS97748.1 - 3.1e-10 39.9 0.0 5.4e-10 39.0 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXS97748.1 - 1.1e-09 38.4 0.2 7e-07 29.1 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXS97748.1 - 6.1e-05 23.2 0.3 0.00013 22.1 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXS97748.1 - 0.00014 21.1 2.0 0.0023 17.1 0.5 2.1 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 KXS97748.1 - 0.00025 20.3 1.3 0.0011 18.1 1.3 1.8 1 1 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KXS97748.1 - 0.00085 18.8 1.5 0.0021 17.5 1.5 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXS97748.1 - 0.0012 18.1 0.0 0.0047 16.2 0.0 1.8 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 KXS97748.1 - 0.011 15.0 0.4 0.032 13.5 0.2 1.6 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KXS97748.1 - 0.026 14.2 0.2 0.059 13.0 0.1 1.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 KXS97748.1 - 0.038 13.0 0.1 0.1 11.6 0.2 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein Shikimate_DH PF01488.20 KXS97748.1 - 0.047 13.7 0.0 0.08 13.0 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 KXS97748.1 - 0.053 14.1 0.1 0.13 12.8 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.23 KXS97748.1 - 0.06 13.3 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HI0933_like PF03486.14 KXS97748.1 - 0.079 11.6 0.1 0.14 10.8 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.14 KXS97748.1 - 0.22 10.4 2.5 0.63 8.8 0.1 2.2 3 0 0 3 3 3 0 Tryptophan halogenase BLM10_mid PF16507.5 KXS97749.1 - 8e-201 668.2 0.0 2.8e-200 666.4 0.0 1.8 2 0 0 2 2 2 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 KXS97749.1 - 1.1e-29 102.1 0.0 1.7e-28 98.4 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3437) BLM10_N PF16547.5 KXS97749.1 - 9.9e-18 64.2 0.3 5.6e-17 61.8 0.0 2.5 2 0 0 2 2 2 1 Proteasome-substrate-size regulator, N-terminal HEAT PF02985.22 KXS97749.1 - 0.00035 20.6 0.2 2.1 8.8 0.0 5.0 4 0 0 4 4 4 1 HEAT repeat CLASP_N PF12348.8 KXS97749.1 - 0.0048 16.5 0.1 0.23 11.0 0.0 2.9 3 0 0 3 3 3 1 CLASP N terminal Glyco_hydro_3 PF00933.21 KXS97750.1 - 5.2e-60 203.5 0.1 6.6e-60 203.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain DUF4148 PF13663.6 KXS97750.1 - 5 7.4 7.5 19 5.5 0.0 4.1 5 0 0 5 5 5 0 Domain of unknown function (DUF4148) Ribosomal_L31e PF01198.19 KXS97753.1 - 1.8e-40 137.1 0.4 2.4e-40 136.6 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e Acyltransferase PF01553.21 KXS97754.1 - 2.5e-31 108.1 0.0 4.6e-31 107.2 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Sugar_tr PF00083.24 KXS97755.1 - 9.5e-115 384.0 17.2 1.1e-114 383.8 17.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS97755.1 - 6.5e-31 107.5 54.8 4.3e-25 88.4 27.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KXS97755.1 - 0.00044 18.7 1.0 0.00044 18.7 1.0 1.7 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family CN_hydrolase PF00795.22 KXS97756.1 - 0.032 13.6 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 Carbon-nitrogen hydrolase TMEM208_SND2 PF05620.11 KXS97756.1 - 0.079 12.7 0.0 0.2 11.4 0.0 1.6 1 1 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 Lipase_3 PF01764.25 KXS97757.1 - 5.8e-19 68.4 0.0 1e-18 67.6 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KXS97757.1 - 0.00071 20.2 0.0 0.00071 20.2 0.0 2.4 1 1 2 3 3 3 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KXS97757.1 - 0.0033 17.2 0.0 0.0066 16.2 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein NTP_transferase PF00483.23 KXS97758.1 - 1.5e-53 181.9 0.0 3e-53 181.0 0.0 1.5 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 KXS97758.1 - 4e-15 54.8 6.8 5.9e-12 44.8 2.1 3.8 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KXS97758.1 - 1.4e-10 41.8 0.0 1.8e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 KXS97758.1 - 1.1e-05 25.0 2.0 1.1e-05 25.0 2.0 3.2 3 1 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 KXS97758.1 - 0.00033 19.0 0.3 0.00093 17.4 0.1 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4954) IspD PF01128.19 KXS97758.1 - 0.092 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase DUF3328 PF11807.8 KXS97759.1 - 1.2e-23 84.0 0.1 1.8e-23 83.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Bot1p PF12298.8 KXS97760.1 - 2.9e-49 167.5 1.1 2.9e-49 167.5 1.1 2.0 2 1 0 2 2 2 1 Eukaryotic mitochondrial regulator protein BTB PF00651.31 KXS97761.1 - 5.2e-13 49.2 0.0 1.1e-12 48.2 0.0 1.5 1 1 0 1 1 1 1 BTB/POZ domain Sdh_cyt PF01127.22 KXS97762.1 - 5.6e-14 52.2 5.1 5.6e-14 52.2 5.1 1.4 2 0 0 2 2 2 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit BTB PF00651.31 KXS97763.1 - 1.9e-17 63.5 0.0 2.6e-10 40.5 0.0 2.3 2 0 0 2 2 2 2 BTB/POZ domain Rad60-SLD PF11976.8 KXS97765.1 - 8.4e-12 44.8 0.0 1e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KXS97765.1 - 2.9e-05 23.7 0.0 3.4e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Phycoerythr_ab PF02972.14 KXS97765.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.4 1 1 0 1 1 1 0 Phycoerythrin, alpha/beta chain T4SS PF07996.11 KXS97779.1 - 0.02 15.3 7.5 0.047 14.1 7.5 1.6 1 0 0 1 1 1 0 Type IV secretion system proteins BUD22 PF09073.10 KXS97779.1 - 0.15 11.3 19.6 0.25 10.6 14.4 2.7 2 0 0 2 2 2 0 BUD22 TetR_C_33 PF13305.6 KXS97779.1 - 7 7.4 7.7 12 6.7 2.1 3.2 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain HEPN_SAV_6107 PF18726.1 KXS97779.1 - 9.7 6.8 12.8 0.14 12.7 2.5 3.2 3 0 0 3 3 3 0 SAV_6107-like HEPN Rep-A_N PF04057.12 KXS97781.1 - 0.19 11.8 0.0 0.39 10.8 0.0 1.4 1 0 0 1 1 1 0 Replication factor-A protein 1, N-terminal domain Cwf_Cwc_15 PF04889.12 KXS97781.1 - 0.2 11.4 13.6 0.018 14.8 8.4 1.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.10 KXS97781.1 - 1.2 9.5 7.2 2.9 8.3 7.2 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CDK2AP PF09806.9 KXS97784.1 - 0.028 14.5 0.9 0.04 14.0 0.9 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Apt1 PF10351.9 KXS97784.1 - 0.22 10.3 2.4 0.27 10.1 2.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ecl1 PF12855.7 KXS97784.1 - 0.62 11.2 14.3 0.55 11.4 12.4 1.7 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins MSP1_C PF07462.11 KXS97785.1 - 0.13 10.9 0.3 0.18 10.4 0.3 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF3847 PF12958.7 KXS97786.1 - 0.054 13.6 0.6 0.13 12.4 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3847) RUN PF02759.19 KXS97786.1 - 0.094 12.7 2.0 0.19 11.7 2.0 1.4 1 0 0 1 1 1 0 RUN domain DUF3905 PF13045.6 KXS97788.1 - 0.1 12.6 0.0 0.2 11.7 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3905) Trypan_PARP PF05887.11 KXS97789.1 - 0.0073 16.3 6.5 0.012 15.6 6.5 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Sporozoite_P67 PF05642.11 KXS97792.1 - 0.0065 14.6 2.3 0.0072 14.5 2.3 1.0 1 0 0 1 1 1 1 Sporozoite P67 surface antigen CENP-B_dimeris PF09026.10 KXS97792.1 - 0.077 13.4 7.9 0.092 13.1 7.9 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF2457 PF10446.9 KXS97792.1 - 0.16 11.0 6.4 0.16 11.1 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) GCIP PF13324.6 KXS97792.1 - 0.48 10.0 4.1 0.53 9.8 4.1 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Cwf_Cwc_15 PF04889.12 KXS97792.1 - 1 9.1 8.2 1.2 8.8 8.2 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 KXS97792.1 - 2.1 7.6 7.4 2.4 7.4 7.4 1.1 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 KXS97792.1 - 3.6 5.6 6.7 3.7 5.6 6.7 1.0 1 0 0 1 1 1 0 DNA polymerase phi NUC130_3NT PF08158.12 KXS97795.1 - 0.029 14.7 0.2 0.11 12.9 0.0 2.1 2 0 0 2 2 2 0 NUC130/3NT domain CCDC73 PF15818.5 KXS97795.1 - 0.21 9.4 5.1 0.34 8.7 5.1 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 73 family TFIID-31kDa PF02291.15 KXS97803.1 - 4.8e-46 155.8 0.0 6.1e-46 155.5 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit BTB PF00651.31 KXS97804.1 - 0.0059 16.8 0.1 0.026 14.7 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain Prok-RING_4 PF14447.6 KXS97804.1 - 4.1 7.3 18.6 1 9.3 12.1 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Asp PF00026.23 KXS97805.1 - 1.9e-53 181.9 6.0 2.9e-53 181.3 6.0 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXS97805.1 - 7.9e-10 39.3 4.9 6.8e-08 32.9 3.0 3.0 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KXS97805.1 - 0.014 16.0 1.0 13 6.5 0.4 3.3 2 1 0 2 2 2 0 Aspartyl protease TAXi_C PF14541.6 KXS97805.1 - 0.065 13.0 0.0 0.27 11.0 0.0 2.1 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 KXS97805.1 - 0.067 13.8 0.2 18 6.0 0.2 3.1 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease Utp11 PF03998.13 KXS97806.1 - 5.9e-59 200.0 11.4 6.8e-59 199.8 11.4 1.0 1 0 0 1 1 1 1 Utp11 protein Syntaxin-6_N PF09177.11 KXS97806.1 - 0.093 13.3 0.2 0.093 13.3 0.2 2.8 3 1 0 3 3 3 0 Syntaxin 6, N-terminal PulG PF11773.8 KXS97806.1 - 0.14 12.0 1.0 0.32 10.8 1.0 1.7 1 0 0 1 1 1 0 Type II secretory pathway pseudopilin SLATT_5 PF18160.1 KXS97806.1 - 0.14 11.4 0.5 0.24 10.7 0.5 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF4195 PF13836.6 KXS97808.1 - 0.021 14.9 0.2 0.023 14.8 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4195) 60KD_IMP PF02096.20 KXS97809.1 - 0.0016 18.3 0.4 0.0051 16.7 0.1 1.9 2 1 0 2 2 2 1 60Kd inner membrane protein Fungal_trans PF04082.18 KXS97810.1 - 3.6e-22 78.7 0.1 6e-22 77.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS97810.1 - 3.5e-09 36.6 8.4 7.6e-09 35.6 8.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Swi3 PF07962.12 KXS97810.1 - 0.17 11.9 0.8 0.42 10.6 0.1 2.0 2 0 0 2 2 2 0 Replication Fork Protection Component Swi3 Acetyltransf_1 PF00583.25 KXS97815.1 - 1.5e-11 44.6 0.0 2.1e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXS97815.1 - 4.5e-07 29.9 0.0 6.7e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXS97815.1 - 3.2e-05 23.8 0.1 5.5e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KXS97815.1 - 0.00012 22.4 0.0 0.00022 21.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXS97815.1 - 0.0052 16.9 0.4 0.017 15.2 0.1 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 KXS97815.1 - 0.054 13.0 0.1 0.082 12.4 0.0 1.3 1 1 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_1 PF00583.25 KXS97816.1 - 2.3e-11 44.0 0.0 3.8e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXS97816.1 - 7.6e-07 29.1 0.0 1.2e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXS97816.1 - 4.9e-05 23.2 0.1 8.8e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KXS97816.1 - 0.00021 21.6 0.0 0.00038 20.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXS97816.1 - 0.0046 17.0 0.2 0.026 14.6 0.1 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 KXS97816.1 - 0.094 12.2 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative acetyl-transferase Ofd1_CTDD PF10637.9 KXS97817.1 - 6.6e-84 281.3 0.0 6.6e-79 264.9 0.0 2.3 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 KXS97817.1 - 2.6e-25 88.9 0.0 7.7e-25 87.4 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KXS97817.1 - 1.5e-13 51.4 0.0 3e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily COPI_C PF06957.11 KXS97817.1 - 0.3 9.8 2.1 0.5 9.1 2.1 1.3 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus SPX PF03105.19 KXS97818.1 - 9.6e-06 25.8 14.9 0.41 10.5 0.5 4.5 2 1 2 4 4 4 4 SPX domain VTC PF09359.10 KXS97818.1 - 0.00018 21.0 0.1 0.018 14.5 0.0 3.2 2 1 0 2 2 2 1 VTC domain GTP_EFTU_D2 PF03144.25 KXS97818.1 - 0.15 12.5 0.0 0.38 11.2 0.0 1.6 1 0 0 1 1 1 0 Elongation factor Tu domain 2 BLOC1_2 PF10046.9 KXS97819.1 - 0.12 12.7 0.1 0.25 11.6 0.1 1.6 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Put_Phosphatase PF06888.12 KXS97820.1 - 0.15 11.5 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Putative Phosphatase SnoaL PF07366.12 KXS97821.1 - 7.8e-05 22.5 0.0 9.9e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KXS97821.1 - 0.00034 21.2 0.0 0.00047 20.7 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain MARVEL PF01284.23 KXS97822.1 - 0.00045 20.3 14.1 0.0046 17.0 13.8 2.0 1 1 1 2 2 2 1 Membrane-associating domain DUF2214 PF09980.9 KXS97822.1 - 0.18 11.6 8.7 0.67 9.8 7.8 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2214) 5TM-5TMR_LYT PF07694.12 KXS97822.1 - 0.29 10.6 6.9 0.038 13.5 0.8 2.1 1 1 0 2 2 2 0 5TMR of 5TMR-LYT MARVEL PF01284.23 KXS97823.1 - 0.00045 20.3 14.1 0.0046 17.0 13.8 2.0 1 1 1 2 2 2 1 Membrane-associating domain DUF2214 PF09980.9 KXS97823.1 - 0.18 11.6 8.7 0.67 9.8 7.8 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2214) 5TM-5TMR_LYT PF07694.12 KXS97823.1 - 0.29 10.6 6.9 0.038 13.5 0.8 2.1 1 1 0 2 2 2 0 5TMR of 5TMR-LYT RabGAP-TBC PF00566.18 KXS97824.1 - 3.2e-47 161.0 0.1 4.6e-47 160.4 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.6 KXS97824.1 - 1.4e-06 27.8 0.5 0.026 14.4 0.3 3.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KXS97824.1 - 6.1e-05 22.3 2.1 0.13 11.9 0.9 3.4 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 KXS97824.1 - 0.00055 20.3 0.4 0.88 10.1 0.3 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KXS97824.1 - 0.026 14.0 0.8 0.48 10.0 0.3 2.6 2 0 0 2 2 2 0 EF hand GRAM PF02893.20 KXS97824.1 - 0.16 11.9 0.0 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 GRAM domain Pyridoxal_deC PF00282.19 KXS97825.1 - 1.7e-100 336.4 0.0 2.2e-100 336.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain E1-E2_ATPase PF00122.20 KXS97826.1 - 1.8e-34 118.9 21.5 2.2e-29 102.2 0.3 3.5 4 0 0 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KXS97826.1 - 9.7e-26 90.6 9.6 9.7e-26 90.6 9.6 2.5 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KXS97826.1 - 3.7e-19 69.9 0.0 5.7e-16 59.4 0.0 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXS97826.1 - 1.6e-16 60.2 0.0 3.1e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KXS97826.1 - 3.1e-15 55.6 0.3 8.9e-15 54.1 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KXS97826.1 - 0.00075 19.3 0.3 0.0056 16.5 0.3 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Orthopox_F8 PF05886.11 KXS97829.1 - 0.065 13.4 0.1 0.099 12.8 0.1 1.3 1 0 0 1 1 1 0 Orthopoxvirus F8 protein Fungal_trans_2 PF11951.8 KXS97830.1 - 7.7e-09 34.8 0.0 1.3e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS97830.1 - 1.8e-08 34.4 9.6 3.6e-08 33.4 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXS97831.1 - 7.7e-09 34.8 0.0 1.3e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS97831.1 - 1.8e-08 34.4 9.6 3.6e-08 33.4 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ALG11_N PF15924.5 KXS97832.1 - 3.7e-83 278.7 0.0 6.3e-83 277.9 0.0 1.4 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 KXS97832.1 - 1.5e-19 70.2 0.0 2.4e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KXS97832.1 - 9.4e-11 42.3 0.0 1.9e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KXS97832.1 - 0.00083 19.4 0.0 0.0017 18.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 adh_short PF00106.25 KXS97833.1 - 1.1e-36 126.2 0.0 1.3e-36 125.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS97833.1 - 3e-34 118.6 0.0 3.9e-34 118.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS97833.1 - 3e-12 46.8 0.1 5.7e-12 45.9 0.1 1.5 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KXS97833.1 - 0.0055 17.0 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KXS97833.1 - 0.021 14.3 0.0 0.16 11.4 0.0 2.1 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family HI0933_like PF03486.14 KXS97833.1 - 0.03 13.1 0.0 0.043 12.5 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_8 PF13450.6 KXS97833.1 - 0.15 12.3 0.1 0.32 11.3 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Ifi-6-16 PF06140.13 KXS97839.1 - 2.2e-06 27.5 7.7 2.2e-06 27.5 7.7 2.5 2 1 0 2 2 2 1 Interferon-induced 6-16 family Q_salvage PF10343.9 KXS97841.1 - 7.6e-114 380.0 0.0 2.7e-74 250.3 0.0 2.1 2 0 0 2 2 2 2 Potential Queuosine, Q, salvage protein family DUF4909 PF16253.5 KXS97841.1 - 0.096 12.5 0.1 0.23 11.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4909) PSDC PF12588.8 KXS97842.1 - 3.9e-59 198.6 0.0 6e-59 198.0 0.0 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.15 KXS97842.1 - 1.4e-38 132.5 0.0 3e-38 131.4 0.0 1.5 2 0 0 2 2 2 1 Phosphatidylserine decarboxylase Biotin_lipoyl_2 PF13533.6 KXS97842.1 - 0.018 14.8 0.3 0.88 9.5 0.2 2.5 2 0 0 2 2 2 0 Biotin-lipoyl like Biotin_lipoyl PF00364.22 KXS97842.1 - 0.02 14.7 0.1 0.2 11.5 0.1 2.3 2 0 0 2 2 2 0 Biotin-requiring enzyme PIN_11 PF18479.1 KXS97842.1 - 0.1 12.8 0.0 1.2 9.3 0.0 2.2 2 0 0 2 2 2 0 PIN like domain RnfC_N PF13375.6 KXS97842.1 - 0.13 12.3 0.1 3.5 7.6 0.0 2.5 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain Snf7 PF03357.21 KXS97843.1 - 7.9e-23 80.9 10.2 7.9e-23 80.9 10.2 1.6 2 0 0 2 2 2 1 Snf7 Ndc1_Nup PF09531.10 KXS97843.1 - 0.058 12.1 1.7 0.061 12.0 1.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup P53_C PF11619.8 KXS97843.1 - 0.21 11.7 1.5 0.58 10.3 1.1 2.1 1 1 1 2 2 2 0 Transcription factor P53 - C terminal domain YlqD PF11068.8 KXS97843.1 - 1.8 9.0 10.6 0.83 10.0 7.0 2.1 2 0 0 2 2 2 0 YlqD protein TMPIT PF07851.13 KXS97843.1 - 9.4 5.4 6.0 19 4.4 6.0 1.6 1 1 0 1 1 1 0 TMPIT-like protein ProRS-C_1 PF09180.11 KXS97844.1 - 2.7e-24 85.2 0.1 5.4e-24 84.2 0.1 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 KXS97844.1 - 1.5e-19 70.6 0.0 2.5e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KXS97844.1 - 2.8e-17 62.7 0.0 5.9e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain TFCD_C PF12612.8 KXS97845.1 - 9.4e-14 51.7 8.2 5.3e-13 49.2 3.7 3.8 4 1 0 4 4 4 1 Tubulin folding cofactor D C terminal HEAT_2 PF13646.6 KXS97845.1 - 5.3e-05 23.5 0.7 0.8 10.1 0.0 4.5 3 0 0 3 3 3 2 HEAT repeats IFRD PF05004.13 KXS97845.1 - 0.0026 16.9 8.1 0.18 10.9 0.1 3.8 4 0 0 4 4 4 2 Interferon-related developmental regulator (IFRD) Ric8 PF10165.9 KXS97845.1 - 0.033 13.2 0.6 2.2 7.2 0.3 2.3 2 0 0 2 2 2 0 Guanine nucleotide exchange factor synembryn HEAT_EZ PF13513.6 KXS97845.1 - 0.042 14.4 6.9 1.1 9.8 0.0 6.3 6 0 0 6 6 6 0 HEAT-like repeat HEAT PF02985.22 KXS97845.1 - 0.36 11.2 15.2 2.1 8.8 0.0 6.6 7 0 0 7 7 7 0 HEAT repeat Glyco_hydro_18 PF00704.28 KXS97846.1 - 5.4e-81 272.7 0.4 6.2e-81 272.5 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CS PF04969.16 KXS97848.1 - 7.6e-07 30.1 0.3 1.5e-06 29.1 0.3 1.5 1 0 0 1 1 1 1 CS domain Pentapeptide_4 PF13599.6 KXS97849.1 - 2.3e-08 34.1 3.2 0.0029 17.7 0.3 2.9 3 1 0 3 3 3 2 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 KXS97849.1 - 0.0017 18.0 0.0 17 5.2 0.0 3.9 5 0 0 5 5 5 2 Pentapeptide repeats (8 copies) PDR_CDR PF06422.12 KXS97850.1 - 0.064 13.2 0.2 0.38 10.7 0.3 2.1 2 0 0 2 2 2 0 CDR ABC transporter Minor_capsid_1 PF10665.9 KXS97850.1 - 0.2 11.8 0.0 0.46 10.7 0.0 1.5 1 0 0 1 1 1 0 Minor capsid protein WD40 PF00400.32 KXS97852.1 - 1.8e-29 101.3 3.4 1.2e-05 25.9 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS97852.1 - 1e-06 29.0 0.1 2.1 8.7 0.0 4.6 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXS97852.1 - 2.2e-06 26.6 9.6 0.027 13.1 0.3 5.2 2 2 3 5 5 5 2 Nucleoporin Nup120/160 DUF5046 PF16465.5 KXS97852.1 - 0.0068 15.9 0.2 0.026 14.0 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF5046) EzrA PF06160.12 KXS97852.1 - 0.021 13.0 6.3 0.031 12.5 6.3 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA APG6_N PF17675.1 KXS97852.1 - 0.081 13.5 10.5 0.21 12.1 10.5 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region HrpB7 PF09486.10 KXS97852.1 - 0.22 11.9 7.4 0.091 13.2 4.2 1.9 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Sas6_CC PF18594.1 KXS97852.1 - 0.29 10.9 2.2 0.61 9.9 2.2 1.5 1 0 0 1 1 1 0 Sas6/XLF/XRCC4 coiled-coil domain DUF4164 PF13747.6 KXS97852.1 - 0.36 11.1 8.8 0.89 9.9 8.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) DUF1664 PF07889.12 KXS97852.1 - 0.95 9.5 3.8 3 7.9 3.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Cauli_DNA-bind PF03310.13 KXS97852.1 - 1 9.5 2.8 1.9 8.5 2.8 1.4 1 0 0 1 1 1 0 Caulimovirus DNA-binding protein Spc7 PF08317.11 KXS97852.1 - 1.2 7.9 7.0 2.1 7.2 7.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein CLZ PF16526.5 KXS97852.1 - 1.9 8.9 8.3 5 7.6 2.2 2.6 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF848 PF05852.11 KXS97852.1 - 5 7.2 7.5 1.4 9.0 3.3 2.3 3 0 0 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) RabGAP-TBC PF00566.18 KXS97853.1 - 5.7e-40 137.3 0.2 7.6e-40 136.8 0.2 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Sugar_tr PF00083.24 KXS97854.1 - 3.7e-83 279.9 26.8 4.2e-83 279.7 26.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS97854.1 - 5.1e-29 101.3 55.4 2.1e-28 99.3 28.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KXS97854.1 - 0.0022 16.9 6.8 0.0022 16.9 6.8 2.4 2 1 1 3 3 3 1 MFS_1 like family GPI2 PF06432.11 KXS97856.1 - 0.088 12.2 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase DUF5383 PF17355.2 KXS97856.1 - 0.22 11.9 0.0 0.22 11.9 0.0 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5383) CPP1-like PF11833.8 KXS97856.1 - 0.24 11.0 2.8 0.35 10.5 2.8 1.5 1 1 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like BAALC_N PF06989.12 KXS97857.1 - 0.0011 19.3 0.6 0.0019 18.5 0.6 1.4 1 0 0 1 1 1 1 BAALC N-terminus MCM PF00493.23 KXS97858.1 - 2e-102 341.0 0.6 3.3e-102 340.3 0.6 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KXS97858.1 - 5.8e-39 132.8 0.8 1.1e-38 131.9 0.8 1.5 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 KXS97858.1 - 5.4e-31 107.0 3.6 1.3e-30 105.8 3.6 1.7 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 KXS97858.1 - 7.6e-25 87.2 0.1 1.7e-24 86.1 0.1 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KXS97858.1 - 7.6e-22 77.9 2.5 2.8e-21 76.0 1.1 2.8 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 KXS97858.1 - 1.4e-08 34.4 0.0 7.6e-07 28.7 0.0 2.4 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KXS97858.1 - 0.00079 19.2 0.0 0.0018 18.0 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 KXS97858.1 - 0.00098 19.0 0.0 0.0026 17.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXS97858.1 - 0.0035 17.3 0.0 0.014 15.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) F-box-like PF12937.7 KXS97859.1 - 0.0089 15.9 0.1 0.016 15.1 0.1 1.5 1 0 0 1 1 1 1 F-box-like Herpes_UL51 PF04540.13 KXS97859.1 - 0.014 15.1 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL51 protein F-box PF00646.33 KXS97859.1 - 0.017 15.0 0.0 0.044 13.7 0.0 1.8 1 0 0 1 1 1 0 F-box domain GFA PF04828.14 KXS97861.1 - 6.8e-08 32.7 2.2 8.3e-08 32.5 0.0 2.3 3 0 0 3 3 3 1 Glutathione-dependent formaldehyde-activating enzyme Npa1 PF11707.8 KXS97862.1 - 9.3e-86 288.2 0.2 2.1e-85 287.1 0.2 1.6 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 KXS97862.1 - 4.8e-55 186.3 0.6 2e-54 184.2 0.0 2.5 3 0 0 3 3 3 1 Nucleolar pre-ribosomal-associated protein 1 DUF3243 PF11588.8 KXS97862.1 - 0.062 13.6 0.1 0.062 13.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3243) SprT-like PF10263.9 KXS97863.1 - 1.3e-21 76.6 0.0 4.1e-21 74.9 0.0 1.8 2 0 0 2 2 2 1 SprT-like family RNF220 PF15926.5 KXS97863.1 - 0.0024 17.5 0.1 0.0037 16.9 0.1 1.4 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase RNF220 WLM PF08325.10 KXS97863.1 - 0.0079 16.3 0.0 0.019 15.1 0.0 1.5 1 0 0 1 1 1 1 WLM domain zf-Di19 PF05605.12 KXS97863.1 - 0.093 13.0 0.1 0.18 12.1 0.1 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding ThiF PF00899.21 KXS97865.1 - 5.3e-69 232.3 0.1 7.7e-69 231.7 0.1 1.1 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.9 KXS97865.1 - 9e-11 42.2 0.2 1.1e-06 28.7 0.2 2.4 1 1 1 2 2 2 2 Ubiquitin-activating enzyme active site UAE_UbL PF14732.6 KXS97865.1 - 5.9e-07 30.0 0.7 1.3e-06 28.9 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.6 KXS97865.1 - 0.022 15.2 0.7 0.35 11.3 0.3 2.9 2 1 0 2 2 2 0 Putative NAD(P)-binding adh_short PF00106.25 KXS97868.1 - 3.8e-33 114.6 1.1 3.1e-19 69.2 0.1 3.1 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXS97868.1 - 1.2e-25 90.4 0.4 2.9e-14 53.2 0.0 2.9 3 0 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS97868.1 - 5.4e-05 23.2 0.0 8.6e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 KR domain AA_permease PF00324.21 KXS97870.1 - 1.5e-114 383.2 40.3 1.9e-114 383.0 40.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXS97870.1 - 1.1e-22 80.4 41.2 1.6e-22 79.9 40.7 1.4 1 1 0 1 1 1 1 Amino acid permease Anoctamin PF04547.12 KXS97871.1 - 7.2e-114 381.1 0.1 9e-114 380.8 0.1 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel HMA PF00403.26 KXS97872.1 - 2.5e-14 53.5 0.0 4.7e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.20 KXS97872.1 - 3.9e-08 33.6 0.1 5.9e-08 33.0 0.1 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Epimerase PF01370.21 KXS97873.1 - 1.7e-19 70.3 0.0 3.1e-19 69.4 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXS97873.1 - 2.9e-19 69.2 0.0 3.8e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KXS97873.1 - 2.7e-13 50.0 0.1 2.6e-08 33.6 0.0 3.1 3 0 0 3 3 3 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KXS97873.1 - 3e-12 46.3 0.0 4.1e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KXS97873.1 - 1.6e-08 34.7 0.2 4.7e-08 33.1 0.2 1.9 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KXS97873.1 - 1.3e-05 25.2 0.2 3.1e-05 24.0 0.2 1.6 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXS97873.1 - 3.5e-05 23.1 0.0 5.5e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KXS97873.1 - 0.00012 21.8 0.1 0.00021 20.9 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 KXS97873.1 - 0.0025 17.3 0.2 0.0062 16.0 0.1 1.8 2 0 0 2 2 2 1 short chain dehydrogenase F420_oxidored PF03807.17 KXS97873.1 - 0.0028 18.2 0.0 0.011 16.3 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KXS97873.1 - 0.0043 17.2 0.0 0.01 16.0 0.0 1.7 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Pkinase PF00069.25 KXS97874.1 - 1.9e-41 142.2 0.1 8e-22 77.9 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pyr_redox_3 PF13738.6 KXS97874.1 - 3.6e-15 56.0 0.0 8.4e-14 51.5 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pkinase_Tyr PF07714.17 KXS97874.1 - 3.8e-13 49.3 0.6 3.5e-09 36.3 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pyr_redox_2 PF07992.14 KXS97874.1 - 4.2e-13 49.2 0.0 1.2e-11 44.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KXS97874.1 - 2.1e-12 46.2 0.0 1.5e-09 36.9 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KXS97874.1 - 6e-06 25.6 0.1 0.00018 20.7 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KXS97874.1 - 6.2e-05 23.2 0.0 0.001 19.3 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KXS97874.1 - 0.00054 19.3 0.1 0.0044 16.3 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 KXS97874.1 - 0.001 19.6 0.3 0.51 10.9 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXS97874.1 - 0.13 11.0 0.0 0.22 10.2 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein TrkA_N PF02254.18 KXS97874.1 - 0.19 12.0 0.0 0.82 9.9 0.0 2.1 3 0 0 3 3 3 0 TrkA-N domain 3HCDH_N PF02737.18 KXS97874.1 - 0.22 11.4 0.2 14 5.5 0.0 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MFS_1 PF07690.16 KXS97875.1 - 6.4e-19 68.1 10.3 7.6e-19 67.8 10.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_127 PF07944.12 KXS97876.1 - 8.5e-21 74.0 0.0 2.1e-20 72.8 0.0 1.5 2 0 0 2 2 2 1 Beta-L-arabinofuranosidase, GH127 Orai-1 PF07856.12 KXS97876.1 - 0.45 10.2 4.0 0.98 9.1 4.0 1.5 1 0 0 1 1 1 0 Mediator of CRAC channel activity DUF4149 PF13664.6 KXS97876.1 - 3.8 7.9 9.1 20 5.6 0.0 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF4149) Peptidase_M28 PF04389.17 KXS97877.1 - 1.7e-30 106.2 0.1 2.5e-30 105.6 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KXS97877.1 - 2.6e-11 43.4 0.4 6.1e-11 42.2 0.4 1.7 1 0 0 1 1 1 1 PA domain DUF5115 PF17142.4 KXS97877.1 - 0.007 16.1 0.1 0.016 14.9 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5115) Peptidase_M20 PF01546.28 KXS97877.1 - 0.011 15.5 0.1 0.029 14.1 0.1 1.8 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 Fungal_trans_2 PF11951.8 KXS97880.1 - 8.6e-15 54.4 8.4 1.2e-13 50.6 8.4 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS97880.1 - 1.5e-06 28.3 10.6 2.6e-06 27.4 10.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COesterase PF00135.28 KXS97881.1 - 1.3e-82 278.3 0.0 2.5e-75 254.3 0.1 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KXS97881.1 - 2.3e-11 44.0 0.6 1.6e-10 41.2 0.6 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXS97881.1 - 0.0049 16.4 0.6 0.0076 15.7 0.6 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family F-box-like PF12937.7 KXS97883.1 - 0.012 15.5 1.4 0.019 14.8 0.0 2.1 2 0 0 2 2 2 0 F-box-like F-box PF00646.33 KXS97883.1 - 0.016 15.1 0.0 0.043 13.7 0.0 1.7 1 0 0 1 1 1 0 F-box domain DUF1749 PF08538.10 KXS97883.1 - 0.15 11.2 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Siva PF05458.12 KXS97885.1 - 0.24 11.1 0.0 0.24 11.1 0.0 1.0 1 0 0 1 1 1 0 Cd27 binding protein (Siva) Siva PF05458.12 KXS97886.1 - 0.24 11.1 0.0 0.24 11.1 0.0 1.0 1 0 0 1 1 1 0 Cd27 binding protein (Siva) Siva PF05458.12 KXS97889.1 - 0.24 11.1 0.0 0.24 11.1 0.0 1.0 1 0 0 1 1 1 0 Cd27 binding protein (Siva) PAP_assoc PF03828.19 KXS97890.1 - 1.4e-08 34.8 0.0 1.4e-08 34.8 0.0 1.8 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KXS97890.1 - 1e-06 28.9 0.0 3.4e-06 27.2 0.0 1.8 1 1 0 1 1 1 1 Nucleotidyltransferase domain Luciferase_N PF05295.11 KXS97890.1 - 0.13 12.2 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 Luciferase/LBP N-terminal domain SR-25 PF10500.9 KXS97890.1 - 4.8 6.7 25.2 11 5.5 25.2 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1349 PF07081.11 KXS97893.1 - 4e-42 144.0 0.1 4.9e-42 143.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) TraN PF06986.11 KXS97894.1 - 0.031 14.0 0.1 0.055 13.2 0.1 1.3 1 0 0 1 1 1 0 Type-1V conjugative transfer system mating pair stabilisation DASH_Duo1 PF08651.10 KXS97896.1 - 6.7e-29 99.5 0.6 1.4e-28 98.5 0.6 1.5 1 0 0 1 1 1 1 DASH complex subunit Duo1 DASH_Dad2 PF08654.10 KXS97896.1 - 0.096 13.1 6.2 0.29 11.6 6.2 1.8 1 1 0 1 1 1 0 DASH complex subunit Dad2 Macoilin PF09726.9 KXS97896.1 - 0.13 10.8 12.4 0.18 10.3 12.4 1.2 1 0 0 1 1 1 0 Macoilin family CDT1_C PF16679.5 KXS97896.1 - 0.26 11.7 7.0 0.33 11.4 0.5 2.5 2 0 0 2 2 2 0 DNA replication factor Cdt1 C-terminal domain PIG-L PF02585.17 KXS97896.1 - 0.85 10.3 3.7 5.6 7.6 3.4 2.3 1 1 0 1 1 1 0 GlcNAc-PI de-N-acetylase DUF4748 PF15932.5 KXS97896.1 - 4.5 7.1 8.4 0.6 9.9 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4748) zf-MYND PF01753.18 KXS97898.1 - 3.9e-08 33.2 11.2 6.4e-08 32.5 11.2 1.4 1 0 0 1 1 1 1 MYND finger Fer4_2 PF12797.7 KXS97898.1 - 6.4 7.1 10.7 8.7 6.7 0.6 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain ATG22 PF11700.8 KXS97899.1 - 0.12 11.0 1.7 0.16 10.5 1.7 1.1 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like Otopetrin PF03189.13 KXS97899.1 - 0.15 10.9 0.1 0.2 10.4 0.1 1.1 1 0 0 1 1 1 0 Otopetrin Ribosomal_S24e PF01282.19 KXS97903.1 - 2.2e-35 120.4 0.2 4.1e-35 119.6 0.0 1.5 1 1 1 2 2 2 1 Ribosomal protein S24e BTB PF00651.31 KXS97904.1 - 2e-10 40.9 0.0 3.3e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Glycos_transf_2 PF00535.26 KXS97905.1 - 8.1e-24 84.3 0.0 4e-23 82.1 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KXS97905.1 - 1.8e-06 28.0 0.0 0.0067 16.3 0.0 3.1 2 1 1 3 3 3 3 Glycosyltransferase like family 2 FGGY_C PF02782.16 KXS97906.1 - 4.7e-73 245.1 1.3 1.3e-72 243.7 0.9 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KXS97906.1 - 4.7e-64 216.3 0.0 7.1e-64 215.7 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Nup96 PF12110.8 KXS97907.1 - 2.6e-65 220.4 0.0 4.3e-65 219.7 0.0 1.4 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 KXS97907.1 - 2.3e-46 157.6 0.0 4.1e-46 156.8 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 KXS97907.1 - 3.7e-32 111.0 361.6 4.5e-12 46.6 37.4 11.4 3 1 8 11 11 11 4 Nucleoporin FG repeat region VHL_C PF17211.3 KXS97907.1 - 0.024 14.6 0.5 1.2 9.3 0.1 2.5 2 0 0 2 2 2 0 VHL box domain DUF4520 PF15016.6 KXS97908.1 - 0.016 15.3 0.1 0.016 15.3 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4520) Tudor_2 PF18104.1 KXS97908.1 - 0.038 13.7 0.1 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 Jumonji domain-containing protein 2A Tudor domain Mito_carr PF00153.27 KXS97909.1 - 6.1e-63 208.8 1.7 3.6e-22 78.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Acetyltransf_2 PF00797.17 KXS97910.1 - 1.7e-29 103.3 0.4 8.8e-29 101.0 0.4 1.9 1 1 0 1 1 1 1 N-acetyltransferase Transglut_core PF01841.19 KXS97910.1 - 0.016 15.7 0.2 0.032 14.7 0.2 1.5 1 0 0 1 1 1 0 Transglutaminase-like superfamily SET PF00856.28 KXS97915.1 - 4.9e-12 46.6 0.0 4.6e-11 43.4 0.0 2.3 1 1 0 1 1 1 1 SET domain Pkinase PF00069.25 KXS97916.1 - 5.6e-64 216.0 0.0 7e-64 215.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS97916.1 - 2.2e-31 109.1 0.0 7.1e-31 107.4 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXS97916.1 - 4.3e-05 23.6 0.0 0.015 15.2 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXS97916.1 - 0.00029 19.9 0.0 0.00041 19.4 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KXS97916.1 - 0.056 12.2 0.0 0.093 11.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 KXS97916.1 - 0.094 11.7 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 AMP-binding PF00501.28 KXS97917.1 - 1e-89 301.1 0.0 1.3e-89 300.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXS97917.1 - 5e-18 65.9 0.1 1.6e-17 64.3 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PLAC8 PF04749.17 KXS97918.1 - 2.7e-19 70.0 16.6 4e-19 69.4 16.6 1.3 1 0 0 1 1 1 1 PLAC8 family DUF1992 PF09350.10 KXS97919.1 - 1e-24 86.5 0.5 3.4e-24 84.8 0.5 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) FliG_C PF01706.16 KXS97919.1 - 0.16 12.2 0.1 0.16 12.2 0.1 3.1 3 1 0 3 3 3 0 FliG C-terminal domain baeRF_family12 PF18856.1 KXS97919.1 - 2.8 8.5 5.4 7.3 7.2 0.6 2.8 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 12 WD40 PF00400.32 KXS97922.1 - 2.1e-37 126.4 27.2 7.7e-07 29.7 0.1 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.7 KXS97922.1 - 6.6e-10 38.7 1.1 1.2e-09 37.9 1.1 1.5 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 KXS97922.1 - 4.9e-08 33.2 0.3 0.18 12.1 0.0 5.9 1 1 6 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXS97922.1 - 0.00016 20.4 5.1 1.7 7.2 0.0 5.5 1 1 5 6 6 6 2 Nucleoporin Nup120/160 F-box PF00646.33 KXS97922.1 - 0.00039 20.2 1.4 0.00076 19.3 1.4 1.5 1 0 0 1 1 1 1 F-box domain WD40_like PF17005.5 KXS97922.1 - 0.015 14.6 0.0 0.087 12.1 0.0 2.0 1 1 1 2 2 2 0 WD40-like domain Glycoprot_B_PH1 PF17416.2 KXS97922.1 - 0.11 12.1 0.4 0.18 11.4 0.4 1.3 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B PQQ_3 PF13570.6 KXS97922.1 - 2.3 8.8 8.0 56 4.4 0.3 5.1 5 1 0 5 5 5 0 PQQ-like domain Sulfate_transp PF00916.20 KXS97923.1 - 1.3e-83 280.8 13.9 2.1e-83 280.2 13.9 1.3 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KXS97923.1 - 2.8e-13 49.5 0.0 7.3e-13 48.2 0.0 1.7 2 0 0 2 2 2 1 STAS domain STAS_2 PF13466.6 KXS97923.1 - 0.18 12.1 0.0 0.46 10.9 0.0 1.7 1 0 0 1 1 1 0 STAS domain MotB_plug PF13677.6 KXS97923.1 - 0.42 10.2 1.4 0.98 9.1 1.4 1.5 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB Read-through PF16814.5 KXS97924.1 - 0.048 13.4 0.0 0.22 11.3 0.0 1.8 2 0 0 2 2 2 0 Read-through domain MIP PF00230.20 KXS97925.1 - 1.8e-56 191.4 6.2 2.2e-56 191.1 6.2 1.1 1 0 0 1 1 1 1 Major intrinsic protein MFS_1 PF07690.16 KXS97926.1 - 1.5e-31 109.7 65.8 3.8e-25 88.6 39.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily R3H PF01424.22 KXS97926.1 - 5.5e-07 29.5 0.2 1.1e-06 28.5 0.2 1.5 1 0 0 1 1 1 1 R3H domain DUF3295 PF11702.8 KXS97926.1 - 0.00092 18.7 14.3 0.014 14.8 14.3 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3295) zf-C2H2 PF00096.26 KXS97926.1 - 1.5 9.4 12.7 2.4 8.8 3.9 3.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS97926.1 - 6.2 7.9 16.5 0.4 11.6 1.6 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger E1_dh PF00676.20 KXS97928.1 - 5.1e-114 380.3 1.7 6.4e-114 379.9 1.7 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KXS97928.1 - 0.015 14.5 0.2 0.032 13.4 0.2 1.5 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase GDC-P PF02347.16 KXS97928.1 - 0.15 10.9 0.3 6.3 5.5 0.1 2.1 2 0 0 2 2 2 0 Glycine cleavage system P-protein Mito_carr PF00153.27 KXS97929.1 - 1.7e-46 156.0 5.4 1.7e-15 56.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Thioredoxin PF00085.20 KXS97930.1 - 5.4e-05 23.1 0.0 0.00021 21.2 0.0 1.8 1 1 1 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 KXS97930.1 - 0.14 12.6 0.0 0.17 12.3 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain Pescadillo_N PF06732.11 KXS97932.1 - 2.8e-124 414.1 0.2 2.8e-124 414.1 0.2 2.1 2 0 0 2 2 2 1 Pescadillo N-terminus MFS_1 PF07690.16 KXS97932.1 - 7.2e-20 71.2 0.5 5.5e-19 68.3 0.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily BRCT_2 PF16589.5 KXS97932.1 - 2.5e-05 24.6 0.0 6.6e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KXS97932.1 - 0.012 15.9 0.0 0.045 14.1 0.0 2.0 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KXS97932.1 - 0.081 13.2 0.0 0.27 11.5 0.0 2.0 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain PIG-U PF06728.13 KXS97933.1 - 1.4e-102 343.6 21.8 1.6e-102 343.4 21.8 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U DAGK_cat PF00781.24 KXS97934.1 - 4.6e-25 87.7 0.1 1.2e-24 86.3 0.0 1.8 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain DUF3653 PF12375.8 KXS97934.1 - 0.0033 17.5 0.0 0.0078 16.3 0.0 1.6 1 0 0 1 1 1 1 Phage protein Tim54 PF11711.8 KXS97934.1 - 0.021 13.6 0.7 0.26 10.0 0.0 2.0 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DUF1840 PF08895.11 KXS97934.1 - 0.15 12.4 0.1 0.36 11.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) p450 PF00067.22 KXS97939.1 - 2.8e-39 135.2 0.0 3.5e-39 134.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glycos_transf_3 PF00591.21 KXS97940.1 - 2.4e-60 204.2 0.0 4.1e-60 203.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 KXS97940.1 - 3.5e-10 39.6 0.5 7.7e-10 38.5 0.5 1.6 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Cyclin_C PF02984.19 KXS97940.1 - 0.45 10.6 2.9 2.6 8.2 0.2 2.2 2 0 0 2 2 2 0 Cyclin, C-terminal domain DUF4470 PF14737.6 KXS97941.1 - 8.8e-07 29.0 0.0 2.1e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_11 PF13414.6 KXS97941.1 - 0.0002 20.9 0.8 0.00044 19.9 0.8 1.6 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.17 KXS97941.1 - 0.011 15.8 9.0 0.08 13.1 0.6 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXS97941.1 - 0.14 12.0 11.1 0.051 13.4 1.8 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXS97941.1 - 0.86 10.0 7.1 12 6.4 0.8 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KXS97941.1 - 1.7 9.2 12.3 6.2 7.4 3.1 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXS97941.1 - 3.4 8.0 8.0 21 5.5 3.6 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat Dehydratase_hem PF13816.6 KXS97942.1 - 9.9e-89 297.8 0.0 1.1e-88 297.6 0.0 1.0 1 0 0 1 1 1 1 Haem-containing dehydratase TMEM239 PF15841.5 KXS97942.1 - 0.28 11.1 4.0 0.56 10.1 4.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 239 family TPR_2 PF07719.17 KXS97944.1 - 1e-05 25.3 3.7 0.022 14.8 0.0 5.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXS97944.1 - 9.9e-05 22.1 1.4 4.2 7.6 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXS97944.1 - 0.045 14.3 3.9 0.26 11.8 0.3 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 KXS97944.1 - 0.047 13.3 0.2 0.4 10.3 0.0 2.4 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_8 PF13181.6 KXS97944.1 - 0.05 13.8 0.0 24 5.5 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXS97944.1 - 0.11 12.3 0.7 2.9 7.8 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Sugar_tr PF00083.24 KXS97946.1 - 1.1e-103 347.5 16.3 1.3e-103 347.3 16.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS97946.1 - 2.7e-15 56.2 36.3 6.6e-13 48.3 12.0 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KXS97946.1 - 0.16 10.2 3.1 0.18 10.1 1.8 1.8 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family FAD_binding_7 PF03441.14 KXS97947.1 - 8.4e-47 159.3 0.3 1.6e-46 158.4 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KXS97947.1 - 1.5e-18 67.3 0.0 2.8e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase ANAPC_CDC26 PF10471.9 KXS97948.1 - 0.0058 17.4 1.8 0.047 14.5 0.0 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex APC subunit CDC26 DUF1664 PF07889.12 KXS97948.1 - 0.049 13.7 0.3 0.087 12.9 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DASH_Dad2 PF08654.10 KXS97948.1 - 0.06 13.8 1.5 1.8 9.0 0.2 2.5 2 1 1 3 3 3 0 DASH complex subunit Dad2 Exonuc_VII_L PF02601.15 KXS97948.1 - 0.075 12.6 2.6 0.083 12.4 2.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DASH_Dam1 PF08653.10 KXS97948.1 - 0.12 12.2 0.1 18 5.2 0.0 2.3 2 0 0 2 2 2 0 DASH complex subunit Dam1 CorA PF01544.18 KXS97948.1 - 0.17 11.1 1.9 0.36 10.1 1.8 1.6 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein PRKG1_interact PF15898.5 KXS97948.1 - 0.29 12.1 3.2 0.26 12.2 1.1 1.8 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain AAA PF00004.29 KXS97949.1 - 2.1e-46 157.6 0.0 7.4e-42 142.9 0.0 3.0 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXS97949.1 - 3.4e-09 36.4 0.0 1.2e-08 34.6 0.0 2.0 1 0 0 1 1 1 1 AAA+ lid domain IstB_IS21 PF01695.17 KXS97949.1 - 8.3e-07 28.9 0.0 3.8e-06 26.8 0.0 2.1 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 KXS97949.1 - 6.6e-06 26.6 0.0 4.5e-05 23.9 0.0 2.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 KXS97949.1 - 1.1e-05 25.6 0.1 4e-05 23.8 0.0 2.0 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) Bromodomain PF00439.25 KXS97949.1 - 0.00034 20.6 0.0 0.00089 19.3 0.0 1.6 1 0 0 1 1 1 1 Bromodomain AAA_5 PF07728.14 KXS97949.1 - 0.00071 19.6 0.0 0.0036 17.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXS97949.1 - 0.0025 18.1 0.1 0.033 14.4 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KXS97949.1 - 0.0027 17.3 0.0 0.023 14.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KXS97949.1 - 0.0038 17.6 0.0 0.0091 16.4 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 KXS97949.1 - 0.004 17.2 0.0 0.018 15.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KXS97949.1 - 0.0071 16.1 0.0 0.02 14.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.6 KXS97949.1 - 0.0082 16.7 0.2 0.055 14.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.6 KXS97949.1 - 0.019 15.1 0.0 1.7 8.8 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain RuvB_N PF05496.12 KXS97949.1 - 0.026 14.3 0.0 0.12 12.1 0.0 2.1 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KXS97949.1 - 0.031 13.5 0.0 0.051 12.8 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain ABC_tran PF00005.27 KXS97949.1 - 0.034 14.7 0.0 0.2 12.2 0.0 2.3 2 0 0 2 2 1 0 ABC transporter NACHT PF05729.12 KXS97949.1 - 0.034 14.1 0.1 0.26 11.2 0.0 2.3 2 0 0 2 2 2 0 NACHT domain Mg_chelatase PF01078.21 KXS97949.1 - 0.036 13.5 0.0 0.085 12.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KXS97949.1 - 0.044 14.0 0.0 0.18 12.0 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KXS97949.1 - 0.045 13.9 0.0 0.045 13.9 0.0 2.4 3 0 0 3 3 1 0 AAA domain Parvo_NS1 PF01057.17 KXS97949.1 - 0.083 12.0 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 KXS97949.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_11 PF13086.6 KXS97949.1 - 0.35 10.6 0.0 0.35 10.6 0.0 3.5 4 0 0 4 4 4 0 AAA domain Methyltransf_23 PF13489.6 KXS97950.1 - 2.1e-14 53.7 0.0 3e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS97950.1 - 5.1e-10 39.9 0.0 9.9e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS97950.1 - 1.3e-09 38.6 0.0 2.8e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS97950.1 - 2.4e-08 33.9 0.0 6e-08 32.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS97950.1 - 3.1e-08 34.2 0.0 7.8e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KXS97950.1 - 0.018 15.1 0.0 0.027 14.6 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.14 KXS97950.1 - 0.21 11.1 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DIOX_N PF14226.6 KXS97951.1 - 2.5e-13 50.8 0.0 3.8e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXS97951.1 - 1.6e-09 38.2 0.0 3.3e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ntox8 PF15545.6 KXS97951.1 - 0.017 15.2 0.2 0.65 10.1 0.0 2.3 1 1 1 2 2 2 0 Bacterial toxin 8 Ald_Xan_dh_C2 PF02738.18 KXS97951.1 - 0.025 13.0 0.0 0.036 12.5 0.0 1.1 1 0 0 1 1 1 0 Molybdopterin-binding domain of aldehyde dehydrogenase ANAPC4_WD40 PF12894.7 KXS97952.1 - 2.7e-05 24.4 0.0 1 9.7 0.0 4.2 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Kelch_4 PF13418.6 KXS97953.1 - 4.5e-05 23.4 0.0 3.9 7.6 0.0 4.5 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.6 KXS97953.1 - 8.8e-05 22.7 0.1 0.019 15.3 0.0 3.8 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.15 KXS97953.1 - 0.0003 20.7 0.0 0.09 12.8 0.0 3.5 3 0 0 3 3 3 1 Kelch motif Wzy_C PF04932.15 KXS97953.1 - 0.0071 16.0 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 O-Antigen ligase DUF1180 PF06679.12 KXS97953.1 - 0.011 16.2 0.0 0.011 16.2 0.0 3.2 2 1 2 4 4 4 0 Protein of unknown function (DUF1180) Kelch_3 PF13415.6 KXS97953.1 - 0.015 15.6 0.0 0.47 10.8 0.0 3.3 2 0 0 2 2 2 0 Galactose oxidase, central domain DUF2681 PF10883.8 KXS97953.1 - 0.17 12.3 0.0 0.33 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) UTP25 PF06862.12 KXS97960.1 - 2.2e-180 600.5 0.0 2.8e-180 600.1 0.0 1.1 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Helicase_C PF00271.31 KXS97960.1 - 0.021 15.2 0.0 0.088 13.2 0.0 2.0 2 0 0 2 2 2 0 Helicase conserved C-terminal domain CDC27 PF09507.10 KXS97960.1 - 0.19 11.1 11.7 0.28 10.5 11.7 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Mpp10 PF04006.12 KXS97961.1 - 1.4e-111 373.9 59.2 1.2e-110 370.9 59.2 2.2 1 1 0 1 1 1 1 Mpp10 protein DUF4914 PF16260.5 KXS97961.1 - 0.18 9.9 0.0 0.28 9.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4914) Zn_clus PF00172.18 KXS97963.1 - 1e-08 35.1 8.8 1.7e-08 34.4 8.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXS97963.1 - 0.0044 15.9 0.0 0.0067 15.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-HC5HC2H PF13771.6 KXS97967.1 - 0.11 12.7 1.9 0.25 11.6 1.9 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain BenE PF03594.13 KXS97970.1 - 0.017 14.0 2.2 0.021 13.6 2.2 1.1 1 0 0 1 1 1 0 Benzoate membrane transport protein Drc1-Sld2 PF11719.8 KXS97971.1 - 0.0014 18.2 7.7 0.0016 18.1 7.7 1.1 1 0 0 1 1 1 1 DNA replication and checkpoint protein BSP_II PF05432.11 KXS97971.1 - 0.01 15.6 11.3 0.014 15.1 11.3 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Sporozoite_P67 PF05642.11 KXS97971.1 - 0.015 13.4 3.4 0.015 13.4 3.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RXT2_N PF08595.11 KXS97971.1 - 0.027 14.5 7.3 0.036 14.1 7.3 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal CDC45 PF02724.14 KXS97971.1 - 0.03 12.6 8.4 0.03 12.6 8.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2052 PF09747.9 KXS97971.1 - 0.089 12.9 12.5 0.12 12.5 12.5 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Sigma70_ner PF04546.13 KXS97971.1 - 0.18 11.7 12.4 0.22 11.4 12.4 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region FAM176 PF14851.6 KXS97971.1 - 0.18 11.5 8.7 0.28 10.9 8.7 1.3 1 0 0 1 1 1 0 FAM176 family NPR3 PF03666.13 KXS97971.1 - 0.47 9.2 6.9 0.5 9.1 6.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DNA_pol_phi PF04931.13 KXS97971.1 - 0.53 8.3 11.3 0.58 8.2 11.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi TFIIF_alpha PF05793.12 KXS97971.1 - 0.56 8.7 24.3 0.74 8.3 24.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF913 PF06025.12 KXS97971.1 - 0.63 9.0 5.4 0.73 8.8 5.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PBP1_TM PF14812.6 KXS97971.1 - 0.65 10.4 20.8 1.2 9.6 20.8 1.5 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nop14 PF04147.12 KXS97971.1 - 0.75 7.9 16.0 0.92 7.6 16.0 1.1 1 0 0 1 1 1 0 Nop14-like family CPSF100_C PF13299.6 KXS97971.1 - 0.85 9.8 10.4 1.2 9.3 10.4 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Presenilin PF01080.17 KXS97971.1 - 1.2 7.9 5.1 1.2 7.8 5.1 1.1 1 0 0 1 1 1 0 Presenilin YL1 PF05764.13 KXS97971.1 - 1.2 9.2 23.6 1.9 8.5 23.6 1.4 1 1 0 1 1 1 0 YL1 nuclear protein Rhabdo_ncap PF00945.18 KXS97971.1 - 1.4 7.7 4.4 1.6 7.6 4.4 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Pox_RNA_Pol_19 PF05320.12 KXS97971.1 - 1.5 8.8 6.3 2.3 8.2 6.3 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DUF4637 PF15470.6 KXS97971.1 - 1.7 8.4 10.3 2.5 7.8 10.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Peptidase_S30 PF01577.16 KXS97971.1 - 2.1 7.9 9.9 2.7 7.5 9.9 1.2 1 0 0 1 1 1 0 Potyvirus P1 protease CENP-B_dimeris PF09026.10 KXS97971.1 - 2.1 8.8 11.3 3.3 8.1 11.3 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RR_TM4-6 PF06459.12 KXS97971.1 - 2.3 8.0 16.6 3 7.6 16.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Cnd2 PF05786.14 KXS97971.1 - 2.4 6.7 15.5 3 6.4 15.5 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 S-antigen PF05756.11 KXS97971.1 - 3.6 8.0 10.0 6.1 7.3 10.0 1.3 1 0 0 1 1 1 0 S-antigen protein DUF2151 PF10221.9 KXS97971.1 - 3.7 6.0 8.4 4.4 5.8 8.4 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator Glycoprotein_G PF00802.19 KXS97971.1 - 4.1 6.7 8.9 7.5 5.8 8.9 1.4 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G TPR_12 PF13424.6 KXS97972.1 - 1.1e-15 57.6 0.0 1.3e-10 41.4 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 KXS97972.1 - 7.6e-09 35.2 0.0 0.0055 16.5 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXS97972.1 - 0.055 13.3 0.0 0.95 9.4 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KXS97972.1 - 0.061 13.4 0.0 4.8 7.5 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Aldo_ket_red PF00248.21 KXS97973.1 - 1.6e-36 126.0 0.0 2e-34 119.2 0.0 2.3 1 1 0 1 1 1 1 Aldo/keto reductase family Kelch_1 PF01344.25 KXS97974.1 - 3.8e-40 135.2 5.6 2.3e-08 33.5 0.0 7.3 7 2 0 7 7 7 5 Kelch motif Kelch_6 PF13964.6 KXS97974.1 - 1.4e-35 120.4 4.9 3.2e-08 33.6 0.0 6.7 4 1 2 6 6 6 5 Kelch motif Kelch_4 PF13418.6 KXS97974.1 - 1.3e-30 105.2 7.5 1.8e-07 31.1 0.0 5.9 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 KXS97974.1 - 1.9e-19 69.5 9.1 1.5e-05 25.2 0.4 5.8 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KXS97974.1 - 4e-16 58.6 0.1 0.12 12.4 0.1 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 KXS97974.1 - 2.6e-14 52.5 0.1 0.00017 21.4 0.0 5.8 5 1 0 5 5 5 3 Kelch motif DUF1668 PF07893.13 KXS97974.1 - 2.3e-05 23.9 0.3 0.00047 19.6 0.0 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF1668) MitMem_reg PF13012.6 KXS97975.1 - 2.5e-21 76.2 2.0 5e-21 75.2 2.0 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KXS97975.1 - 3.5e-20 72.2 0.0 6.2e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease UPF0172 PF03665.13 KXS97975.1 - 2.4e-05 24.5 0.1 0.00021 21.4 0.0 2.0 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0172) DUF1241 PF06840.11 KXS97975.1 - 0.04 13.6 0.1 0.085 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) DUF4795 PF16043.5 KXS97975.1 - 0.065 12.8 0.4 0.11 12.1 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) DUF150 PF02576.17 KXS97975.1 - 0.065 13.7 0.1 0.19 12.2 0.1 1.7 1 0 0 1 1 1 0 RimP N-terminal domain Anp1 PF03452.14 KXS97977.1 - 3.2e-106 354.6 0.0 3.8e-106 354.3 0.0 1.0 1 0 0 1 1 1 1 Anp1 zf-C2HC_2 PF13913.6 KXS97978.1 - 0.063 13.2 0.3 0.14 12.1 0.3 1.6 1 0 0 1 1 1 0 zinc-finger of a C2HC-type GPR15L PF15854.5 KXS97978.1 - 2.9 8.2 4.7 2.1 8.6 0.1 2.8 3 0 0 3 3 3 0 G-protein coupled receptor ligand 15 Ecm33 PF12454.8 KXS97979.1 - 4.8e-11 42.6 1.2 8.9e-11 41.8 0.3 2.0 2 0 0 2 2 2 1 GPI-anchored cell wall organization protein Recep_L_domain PF01030.24 KXS97979.1 - 6.8e-06 26.2 2.9 0.56 10.4 0.0 4.3 1 1 2 4 4 4 2 Receptor L domain LRR_5 PF13306.6 KXS97979.1 - 0.00019 21.4 0.7 0.0065 16.4 0.1 2.4 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) Ecm33 PF12454.8 KXS97980.1 - 4.8e-11 42.6 1.2 8.9e-11 41.8 0.3 2.0 2 0 0 2 2 2 1 GPI-anchored cell wall organization protein Recep_L_domain PF01030.24 KXS97980.1 - 6.8e-06 26.2 2.9 0.56 10.4 0.0 4.3 1 1 2 4 4 4 2 Receptor L domain LRR_5 PF13306.6 KXS97980.1 - 0.00019 21.4 0.7 0.0065 16.4 0.1 2.4 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) DEAD PF00270.29 KXS97981.1 - 1.6e-19 70.3 0.0 4.9e-19 68.8 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXS97981.1 - 4e-14 52.9 0.0 2.1e-12 47.4 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KXS97981.1 - 4.2e-11 43.4 0.3 9.5e-11 42.3 0.3 1.6 1 0 0 1 1 1 1 RecQ zinc-binding Dioxygenase_C PF00775.21 KXS97982.1 - 0.00088 18.8 0.0 0.0015 18.0 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase DUF973 PF06157.11 KXS97984.1 - 0.072 12.1 5.6 0.11 11.5 5.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF973) DUF4131 PF13567.6 KXS97984.1 - 0.26 10.9 2.8 3.8 7.1 2.7 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) DUF4293 PF14126.6 KXS97984.1 - 0.67 10.2 8.1 1.1e+02 3.0 8.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) DUF4282 PF14110.6 KXS97984.1 - 0.81 10.5 13.0 4.5 8.1 2.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) DUF4199 PF13858.6 KXS97984.1 - 1.9 8.9 12.0 0.86 10.0 3.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4199) Herpes_LMP1 PF05297.11 KXS97984.1 - 3.5 6.7 6.1 5.1 6.2 6.1 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Tetraspanin PF00335.20 KXS97984.1 - 5.7 6.6 11.1 33 4.1 11.2 1.9 1 1 0 1 1 1 0 Tetraspanin family Abhydrolase_9_N PF15420.6 KXS97984.1 - 8.3 6.4 9.0 14 5.6 1.5 2.4 1 1 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus DUF1757 PF08560.10 KXS97988.1 - 0.075 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1757) PDDEXK_2 PF12784.7 KXS97988.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 PD-(D/E)XK nuclease family transposase Hexapep PF00132.24 KXS97989.1 - 5.3e-14 51.3 10.3 5.7e-05 22.7 0.3 5.1 4 1 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KXS97989.1 - 5.9e-05 22.7 11.1 0.048 13.4 0.6 3.4 3 0 0 3 3 3 3 Hexapeptide repeat of succinyl-transferase Epimerase PF01370.21 KXS97992.1 - 1.1e-05 25.1 0.0 1.6e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Fungal_trans PF04082.18 KXS97993.1 - 1.7e-13 50.2 0.0 2.7e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS97993.1 - 5.1e-06 26.5 9.1 1.1e-05 25.5 9.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zip PF02535.22 KXS97994.1 - 5.5e-59 200.1 0.3 6.4e-59 199.8 0.3 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter HAD_2 PF13419.6 KXS97996.1 - 1.5e-23 83.8 0.0 2.1e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXS97996.1 - 1.1e-10 42.1 0.0 1.3e-09 38.6 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXS97996.1 - 2.6e-05 24.2 0.0 5.1e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 KXS97996.1 - 0.00048 20.6 0.0 0.00089 19.7 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ada_Zn_binding PF02805.16 KXS97997.1 - 5.6e-31 106.4 5.6 9.7e-31 105.6 5.6 1.4 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.23 KXS97997.1 - 8.6e-07 28.9 0.0 1.8e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.7 KXS97997.1 - 0.00011 22.4 0.6 0.0003 21.0 0.2 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain PAN_4 PF14295.6 KXS97998.1 - 0.012 15.5 2.4 0.2 11.6 0.3 3.0 2 0 0 2 2 2 0 PAN domain Suc_Fer-like PF06999.12 KXS97999.1 - 3.5e-68 229.3 0.0 4.2e-68 229.1 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Dehydrin PF00257.19 KXS98000.1 - 0.014 16.0 3.9 0.014 16.0 3.9 4.3 1 1 2 3 3 3 0 Dehydrin Dehydrin PF00257.19 KXS98001.1 - 0.015 15.8 4.1 0.015 15.8 4.1 4.4 1 1 2 3 3 3 0 Dehydrin CPSase_L_D2 PF02786.17 KXS98002.1 - 2.7e-73 246.0 0.0 4e-73 245.4 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 KXS98002.1 - 1.3e-36 125.0 0.0 3.6e-36 123.6 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 KXS98002.1 - 3.6e-30 104.7 0.0 8e-30 103.6 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 KXS98002.1 - 2.8e-16 59.1 1.4 5.8e-16 58.1 1.4 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KXS98002.1 - 1.6e-09 37.6 0.0 3.6e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KXS98002.1 - 9e-09 35.1 0.1 2e-08 34.0 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 KXS98002.1 - 1.7e-07 30.9 0.0 0.011 15.5 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.14 KXS98002.1 - 3.6e-05 23.9 0.0 6.6e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain GCV_H PF01597.19 KXS98002.1 - 0.0091 15.9 0.4 0.04 13.8 0.2 2.0 2 0 0 2 2 2 1 Glycine cleavage H-protein ATPgrasp_ST PF14397.6 KXS98002.1 - 0.025 13.8 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp RimK PF08443.11 KXS98002.1 - 0.049 13.2 0.0 0.14 11.8 0.0 1.7 1 1 0 1 1 1 0 RimK-like ATP-grasp domain Abhydrolase_3 PF07859.13 KXS98003.1 - 1.3e-19 70.9 0.0 2.5e-18 66.7 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXS98003.1 - 1.2e-13 51.0 0.0 9.5e-06 25.2 0.0 2.2 1 1 1 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 KXS98003.1 - 2.1e-07 30.1 0.0 3.1e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KXS98003.1 - 1.4e-06 27.6 0.0 2.1e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Hydrolase_4 PF12146.8 KXS98003.1 - 9.2e-06 25.1 0.0 5.6e-05 22.5 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 KXS98003.1 - 1.1e-05 25.2 0.0 1.9e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Putative esterase AXE1 PF05448.12 KXS98003.1 - 4.3e-05 22.4 0.0 0.065 11.9 0.0 2.0 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 KXS98003.1 - 7.9e-05 22.4 0.0 0.41 10.3 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 KXS98003.1 - 0.00017 21.2 0.0 0.54 9.8 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 KXS98003.1 - 0.00021 21.2 0.0 0.096 12.5 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 KXS98003.1 - 0.00032 21.4 0.8 0.00047 20.8 0.8 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.9 KXS98003.1 - 0.012 15.1 0.0 0.39 10.2 0.0 2.2 2 0 0 2 2 2 0 Esterase PHB depolymerase Say1_Mug180 PF10340.9 KXS98003.1 - 0.075 11.9 0.0 0.17 10.7 0.0 1.4 1 1 0 1 1 1 0 Steryl acetyl hydrolase COesterase PF00135.28 KXS98003.1 - 0.23 10.3 0.0 0.62 8.9 0.0 1.6 2 0 0 2 2 2 0 Carboxylesterase family Aldedh PF00171.22 KXS98004.1 - 3.2e-113 378.7 2.1 3.5e-113 378.6 2.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family BTB PF00651.31 KXS98005.1 - 0.2 11.9 0.0 0.32 11.2 0.0 1.2 1 0 0 1 1 1 0 BTB/POZ domain NOD2_WH PF17779.1 KXS98006.1 - 0.0024 18.1 4.9 19 5.7 0.0 5.7 5 1 1 6 6 6 2 NOD2 winged helix domain SHIRT PF18655.1 KXS98006.1 - 2.3 8.8 3.9 1.6e+02 2.9 0.2 3.9 1 1 2 3 3 3 0 SHIRT domain DUF3425 PF11905.8 KXS98008.1 - 9.4e-20 70.8 0.4 1.3e-19 70.4 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) DUF3425 PF11905.8 KXS98009.1 - 4.5e-19 68.6 0.4 8.5e-19 67.7 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 KXS98009.1 - 0.023 14.8 3.2 0.023 14.8 3.2 2.5 3 0 0 3 3 3 0 bZIP transcription factor Peptidase_C48 PF02902.19 KXS98011.1 - 1.6e-10 41.2 3.6 5e-06 26.5 0.0 3.1 3 1 1 4 4 4 2 Ulp1 protease family, C-terminal catalytic domain FtsJ PF01728.19 KXS98012.1 - 0.017 15.2 0.3 8.6 6.4 0.0 3.5 1 1 4 5 5 5 0 FtsJ-like methyltransferase RICTOR_N PF14664.6 KXS98012.1 - 0.018 14.1 2.6 9.4 5.1 0.0 4.0 1 1 3 4 4 4 0 Rapamycin-insensitive companion of mTOR, N-term FANCD2OS PF15124.6 KXS98012.1 - 0.051 13.8 1.8 3.5 7.8 0.5 3.2 1 1 2 3 3 3 0 FANCD2 opposite strand protein DUF1996 PF09362.10 KXS98013.1 - 1.5e-66 224.8 2.9 3.2e-66 223.7 2.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Ank_4 PF13637.6 KXS98014.1 - 1.4e-08 35.1 0.1 0.00015 22.3 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXS98014.1 - 2.4e-07 31.2 0.0 0.00039 21.0 0.0 2.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXS98014.1 - 0.00015 21.9 0.1 2.8 8.8 0.0 4.8 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 KXS98014.1 - 0.014 15.7 0.2 2.6 8.5 0.0 3.0 2 1 1 3 3 3 0 Ankyrin repeats (many copies) AAA_12 PF13087.6 KXS98015.1 - 1.7e-24 86.6 0.0 4.1e-24 85.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KXS98015.1 - 5.2e-18 65.8 0.0 1.3e-16 61.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KXS98015.1 - 6.4e-05 22.8 0.1 0.0023 17.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KXS98015.1 - 0.0018 18.6 0.0 0.015 15.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain RPA43_OB PF17875.1 KXS98015.1 - 0.013 16.1 4.9 0.024 15.3 3.9 2.0 1 1 0 1 1 1 0 RPA43 OB domain in RNA Pol I AAA PF00004.29 KXS98015.1 - 0.014 15.8 0.1 0.049 14.1 0.1 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 KXS98015.1 - 0.014 15.4 0.0 0.035 14.1 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DBI_PRT PF02277.17 KXS98015.1 - 0.04 13.1 0.1 0.065 12.4 0.1 1.2 1 0 0 1 1 1 0 Phosphoribosyltransferase RuvB_N PF05496.12 KXS98015.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Viral_helicase1 PF01443.18 KXS98015.1 - 0.17 11.6 0.1 0.66 9.7 0.0 1.9 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase HicA_toxin PF07927.12 KXS98022.1 - 0.017 15.1 0.1 0.022 14.8 0.1 1.2 1 0 0 1 1 1 0 HicA toxin of bacterial toxin-antitoxin, DUF1275 PF06912.11 KXS98023.1 - 4e-38 131.3 16.6 4.9e-38 131.0 16.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Tetraspanin PF00335.20 KXS98023.1 - 0.01 15.6 1.1 0.013 15.2 0.3 1.5 1 1 0 1 1 1 0 Tetraspanin family DUF3394 PF11874.8 KXS98023.1 - 0.12 12.0 0.8 0.28 10.8 0.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3394) Tmemb_14 PF03647.13 KXS98023.1 - 0.17 12.6 7.4 1.2 9.9 1.1 2.5 2 0 0 2 2 2 0 Transmembrane proteins 14C AtpR PF12966.7 KXS98023.1 - 1.7 9.1 9.6 4.4 7.8 2.6 2.5 2 0 0 2 2 2 0 N-ATPase, AtpR subunit CHCH PF06747.13 KXS98024.1 - 3.2e-05 23.9 0.2 6e-05 23.1 0.2 1.5 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.9 KXS98024.1 - 0.055 13.8 2.3 0.29 11.5 2.4 2.0 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Choline_kinase PF01633.20 KXS98025.1 - 1.2e-46 159.0 0.1 2.3e-46 158.1 0.0 1.5 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 KXS98025.1 - 1.4e-12 48.0 0.2 2.7e-12 47.1 0.2 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KXS98025.1 - 2.3e-06 27.2 0.0 3.8e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 KXS98025.1 - 0.013 14.3 0.0 0.018 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) His_Phos_1 PF00300.22 KXS98027.1 - 2.2e-31 109.1 0.0 4.5e-31 108.1 0.0 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Rad51 PF08423.11 KXS98028.1 - 2.5e-129 430.0 0.0 3.1e-129 429.7 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KXS98028.1 - 2e-10 40.6 0.0 2.9e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 KXS98028.1 - 4.6e-09 36.1 0.0 6.2e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 KXS98028.1 - 1.2e-05 24.8 0.3 3.5e-05 23.3 0.3 1.9 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.6 KXS98028.1 - 3.1e-05 24.5 0.2 0.00011 22.7 0.1 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain DnaB_C PF03796.15 KXS98028.1 - 0.0046 16.3 0.2 0.02 14.2 0.0 1.9 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_24 PF13479.6 KXS98028.1 - 0.033 13.9 0.0 0.058 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KXS98028.1 - 0.12 12.6 0.1 0.35 11.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain PAXNEB PF05625.11 KXS98028.1 - 0.22 10.6 1.7 0.82 8.7 0.7 2.0 1 1 1 2 2 2 0 PAXNEB protein DUF3808 PF10300.9 KXS98031.1 - 2.3e-139 465.2 0.9 3.2e-139 464.7 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_2 PF07719.17 KXS98031.1 - 0.095 12.9 0.1 20 5.6 0.0 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXS98031.1 - 0.12 12.6 0.2 38 4.9 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KXS98031.1 - 2.1 8.9 5.5 6.6 7.3 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DNase-RNase PF02577.14 KXS98032.1 - 0.15 11.8 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Bifunctional nuclease Sulfate_transp PF00916.20 KXS98033.1 - 1.6e-59 201.6 19.4 2.3e-59 201.1 19.4 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KXS98033.1 - 2.6e-11 43.2 0.0 7.2e-11 41.8 0.0 1.7 1 0 0 1 1 1 1 STAS domain cNMP_binding PF00027.29 KXS98033.1 - 8.8e-11 41.7 0.0 1.7e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS_2 PF13466.6 KXS98033.1 - 0.15 12.4 0.1 0.38 11.1 0.1 1.6 1 0 0 1 1 1 0 STAS domain Ank_2 PF12796.7 KXS98034.1 - 5e-35 120.0 1.1 1.5e-10 41.5 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS98034.1 - 1.4e-34 118.1 3.8 1.7e-08 34.8 0.1 5.1 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXS98034.1 - 1.2e-31 108.3 0.8 1e-09 38.5 0.0 5.0 1 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS98034.1 - 8e-26 87.3 0.0 0.00074 19.8 0.0 6.3 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 KXS98034.1 - 2.5e-22 78.3 1.4 0.0025 18.2 0.0 6.3 6 0 0 6 6 6 5 Ankyrin repeat Sulfate_transp PF00916.20 KXS98035.1 - 1.6e-59 201.6 19.4 2.3e-59 201.1 19.4 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KXS98035.1 - 2.6e-11 43.2 0.0 7.2e-11 41.8 0.0 1.7 1 0 0 1 1 1 1 STAS domain cNMP_binding PF00027.29 KXS98035.1 - 8.8e-11 41.7 0.0 1.7e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS_2 PF13466.6 KXS98035.1 - 0.15 12.4 0.1 0.38 11.1 0.1 1.6 1 0 0 1 1 1 0 STAS domain Sulfate_transp PF00916.20 KXS98037.1 - 1.6e-59 201.6 19.4 2.3e-59 201.1 19.4 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KXS98037.1 - 2.6e-11 43.2 0.0 7.2e-11 41.8 0.0 1.7 1 0 0 1 1 1 1 STAS domain cNMP_binding PF00027.29 KXS98037.1 - 8.8e-11 41.7 0.0 1.7e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS_2 PF13466.6 KXS98037.1 - 0.15 12.4 0.1 0.38 11.1 0.1 1.6 1 0 0 1 1 1 0 STAS domain Pkinase PF00069.25 KXS98039.1 - 3.3e-67 226.6 0.0 5.7e-67 225.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS98039.1 - 3.4e-35 121.6 0.0 5.6e-35 120.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXS98039.1 - 0.00076 19.5 0.6 0.0023 17.9 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KXS98039.1 - 0.0014 18.1 0.0 0.0039 16.6 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 KXS98039.1 - 0.0084 15.2 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 KXS98039.1 - 0.038 12.8 0.0 0.074 11.8 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KXS98039.1 - 0.055 12.8 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PH_6 PF15406.6 KXS98041.1 - 8.8e-26 90.4 0.1 8.8e-26 90.4 0.1 3.0 2 1 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 KXS98041.1 - 0.0015 19.0 0.0 0.0036 17.8 0.0 1.6 1 0 0 1 1 1 1 PH domain Peptidase_S49_N PF08496.10 KXS98041.1 - 2.2 8.4 9.3 7.7 6.6 9.3 2.0 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Nup160 PF11715.8 KXS98042.1 - 8.8e-86 288.7 0.0 1.2e-85 288.2 0.0 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 TPR_19 PF14559.6 KXS98042.1 - 0.13 12.7 8.4 1.4 9.5 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4427 PF14468.6 KXS98042.1 - 0.15 12.1 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4427) TPR_14 PF13428.6 KXS98042.1 - 0.15 12.9 1.9 9.4 7.4 0.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KXS98042.1 - 0.53 11.0 3.0 0.8 10.4 0.4 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXS98042.1 - 0.66 10.2 2.2 2.2 8.6 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Got1 PF04178.12 KXS98043.1 - 3.7e-10 40.2 0.4 5e-10 39.8 0.4 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family Vma12 PF11712.8 KXS98043.1 - 0.058 13.5 0.3 0.07 13.2 0.3 1.1 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF4800 PF16057.5 KXS98043.1 - 0.13 11.5 0.0 0.14 11.4 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4800) Got1 PF04178.12 KXS98045.1 - 9.7e-35 119.4 13.3 1.2e-34 119.1 13.3 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF2632 PF10943.8 KXS98045.1 - 0.19 11.3 8.8 0.25 10.9 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2632) Vma12 PF11712.8 KXS98045.1 - 0.22 11.6 0.5 0.45 10.6 0.5 1.4 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF2070 PF09843.9 KXS98045.1 - 1.3 7.3 5.7 1.6 7.0 5.7 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Got1 PF04178.12 KXS98046.1 - 1.5e-21 76.9 3.3 1.9e-21 76.6 3.3 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Vma12 PF11712.8 KXS98046.1 - 0.16 12.0 0.7 0.22 11.6 0.7 1.3 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase TRI12 PF06609.13 KXS98048.1 - 4.2e-29 101.4 18.8 5.2e-29 101.1 18.8 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KXS98048.1 - 2.2e-19 69.6 46.8 1.3e-16 60.5 44.6 3.1 2 1 0 2 2 2 2 Major Facilitator Superfamily UBD PF16455.5 KXS98049.1 - 1.1e-37 128.4 0.0 1.8e-37 127.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-binding domain DUF2407 PF10302.9 KXS98049.1 - 0.00065 20.2 0.1 0.0018 18.8 0.1 1.8 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_5 PF18037.1 KXS98049.1 - 0.0043 17.4 0.0 0.011 16.0 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 KXS98049.1 - 0.009 15.7 0.0 0.023 14.4 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KXS98049.1 - 0.058 13.2 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like ADH_N PF08240.12 KXS98050.1 - 2.6e-22 78.8 2.1 5.3e-22 77.8 2.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXS98050.1 - 4.3e-19 68.8 0.6 1e-18 67.5 0.6 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KXS98050.1 - 0.022 14.1 0.3 0.038 13.3 0.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SLD3 PF08639.10 KXS98052.1 - 2.7e-116 389.5 17.7 3.5e-116 389.1 17.7 1.1 1 0 0 1 1 1 1 DNA replication regulator SLD3 HLH PF00010.26 KXS98053.1 - 3.1e-11 43.0 0.0 1.6e-10 40.8 0.0 2.2 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3903 PF13043.6 KXS98054.1 - 0.15 11.8 0.0 0.46 10.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3903) WD40 PF00400.32 KXS98055.1 - 1.1e-20 73.6 4.7 0.00027 21.7 0.3 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS98055.1 - 1.8e-15 57.0 0.1 0.1 12.9 0.0 6.2 3 2 3 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KXS98055.1 - 0.0092 15.3 0.1 0.041 13.2 0.0 2.1 3 0 0 3 3 3 1 WD40-like domain HPS3_N PF14761.6 KXS98055.1 - 0.18 11.3 0.0 21 4.6 0.0 2.7 3 1 1 4 4 4 0 Hermansky-Pudlak syndrome 3 Complex1_LYR PF05347.15 KXS98056.1 - 3e-08 33.6 0.1 1e-07 31.9 0.1 1.9 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF3328 PF11807.8 KXS98068.1 - 9.4e-15 55.0 0.4 6.8e-13 48.9 0.2 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF3328) Fumarate_red_D PF02313.17 KXS98068.1 - 0.013 15.6 0.0 0.021 14.9 0.0 1.2 1 0 0 1 1 1 0 Fumarate reductase subunit D Chromo PF00385.24 KXS98069.1 - 1.1e-06 28.5 1.7 3.1e-06 27.0 1.7 1.8 1 1 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Pkinase PF00069.25 KXS98074.1 - 1.7e-27 96.5 0.0 2.3e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS98074.1 - 2.1e-06 27.2 0.0 3.2e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXS98074.1 - 0.0099 15.8 0.5 0.019 14.9 0.1 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family DEC-1_N PF04625.13 KXS98075.1 - 0.11 11.5 7.9 0.17 10.8 7.9 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF5525 PF17663.1 KXS98075.1 - 0.13 10.3 11.2 0.18 9.8 11.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5525) UPF0524 PF15823.5 KXS98076.1 - 0.017 14.5 1.6 0.025 14.0 1.6 1.3 1 0 0 1 1 1 0 UPF0524 of C3orf70 Fib_alpha PF08702.10 KXS98077.1 - 0.038 14.2 0.7 0.056 13.6 0.7 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family TMF_DNA_bd PF12329.8 KXS98077.1 - 0.54 10.3 6.7 0.5 10.4 1.9 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF3328 PF11807.8 KXS98081.1 - 6.8e-35 120.8 7.7 8.4e-35 120.5 7.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF1743 PF08489.11 KXS98083.1 - 4e-07 30.1 0.9 34 4.5 0.0 6.3 1 1 7 8 8 8 3 Domain of unknown function (DUF1743) PROCT PF08084.11 KXS98083.1 - 2.5e-06 27.4 6.7 38 4.2 0.0 7.5 1 1 7 8 8 8 0 PROCT (NUC072) domain Thump_like PF18096.1 KXS98083.1 - 0.022 14.7 0.1 80 3.3 0.0 4.8 7 0 0 7 7 7 0 THUMP domain-like OxoDH_E1alpha_N PF12573.8 KXS98083.1 - 0.054 13.3 9.3 1.1e+02 2.7 0.8 5.8 6 0 0 6 6 6 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal N_NLPC_P60 PF12912.7 KXS98083.1 - 0.39 11.1 1.3 80 3.6 0.1 3.3 1 1 3 4 4 4 0 NLPC_P60 stabilising domain, N term DUF3919 PF13057.6 KXS98084.1 - 0.13 11.8 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3919) DUF2203 PF09969.9 KXS98091.1 - 0.0072 17.0 8.9 1 10.1 2.8 3.2 2 1 1 3 3 3 2 Uncharacterized conserved protein (DUF2203) PX PF00787.24 KXS98091.1 - 0.018 15.0 0.3 2.4 8.2 0.0 2.9 2 1 0 2 2 2 0 PX domain DUF3552 PF12072.8 KXS98091.1 - 0.42 10.0 19.1 0.081 12.3 7.5 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3552) L27_1 PF09058.10 KXS98091.1 - 0.47 10.5 8.0 1.3 9.0 0.0 3.5 4 0 0 4 4 4 0 L27_1 Bacillus_HBL PF05791.11 KXS98091.1 - 0.51 10.1 6.8 7.5 6.3 0.2 2.3 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF3053 PF11254.8 KXS98091.1 - 1.3 8.6 8.8 0.19 11.3 2.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3053) ATG16 PF08614.11 KXS98091.1 - 1.3 9.2 21.2 0.19 11.9 9.6 3.0 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 KXS98091.1 - 3.4 7.7 5.1 15 5.6 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FYVE PF01363.21 KXS98092.1 - 8.1e-05 22.7 0.4 8.1e-05 22.7 0.4 2.4 3 1 0 3 3 3 1 FYVE zinc finger Prok-RING_1 PF14446.6 KXS98092.1 - 0.00037 20.4 2.4 0.00037 20.4 2.4 3.2 4 0 0 4 4 4 1 Prokaryotic RING finger family 1 Zf_RING PF16744.5 KXS98092.1 - 0.0034 17.5 0.2 0.0034 17.5 0.2 2.6 3 0 0 3 3 3 1 KIAA1045 RING finger zf-RING_2 PF13639.6 KXS98092.1 - 0.026 14.9 4.6 0.026 14.9 4.6 4.0 3 2 0 3 3 3 0 Ring finger domain C1_1 PF00130.22 KXS98092.1 - 0.18 11.7 0.1 0.18 11.7 0.1 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 KXS98092.1 - 0.33 10.9 6.5 0.24 11.3 1.1 3.2 4 0 0 4 4 4 0 PHD-finger Trm112p PF03966.16 KXS98092.1 - 1.4 9.6 4.5 4 8.1 0.0 3.1 3 1 0 3 3 3 0 Trm112p-like protein Rad50_zn_hook PF04423.14 KXS98092.1 - 1.7 8.5 4.0 87 3.1 0.1 3.4 3 0 0 3 3 3 0 Rad50 zinc hook motif PhnA_Zn_Ribbon PF08274.12 KXS98092.1 - 4.3 7.4 10.2 1.1 9.2 1.1 3.4 3 0 0 3 3 3 0 PhnA Zinc-Ribbon Fer4_9 PF13187.6 KXS98094.1 - 0.097 12.9 2.3 0.21 11.8 2.3 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain COG7 PF10191.9 KXS98094.1 - 0.13 10.5 0.8 0.17 10.1 0.8 1.1 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) Fer4 PF00037.27 KXS98094.1 - 1.3 9.0 4.8 0.17 11.8 0.7 1.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_6 PF12837.7 KXS98094.1 - 3.4 7.9 5.5 0.29 11.3 0.5 1.7 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_2 PF12797.7 KXS98094.1 - 9.1 6.6 8.8 2.5 8.4 3.1 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Furin-like_2 PF15913.5 KXS98095.1 - 0.0047 17.1 1.4 0.0086 16.2 1.4 1.4 1 0 0 1 1 1 1 Furin-like repeat, cysteine-rich OATP PF03137.20 KXS98095.1 - 0.0053 15.1 0.1 0.0064 14.8 0.1 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family OAD_gamma PF04277.13 KXS98095.1 - 0.0074 16.9 0.0 0.011 16.3 0.0 1.3 1 0 0 1 1 1 1 Oxaloacetate decarboxylase, gamma chain DUF350 PF03994.14 KXS98095.1 - 0.11 12.7 0.1 0.21 11.8 0.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF350) DUF2318 PF10080.9 KXS98095.1 - 0.13 12.4 0.1 0.2 11.8 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) DUF3149 PF11346.8 KXS98098.1 - 0.2 11.3 0.4 0.44 10.2 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) PGF-CTERM PF18204.1 KXS98098.1 - 0.51 10.4 3.0 1.3 9.1 3.0 1.7 1 0 0 1 1 1 0 PGF-CTERM motif DUF3149 PF11346.8 KXS98101.1 - 0.2 11.3 0.4 0.44 10.2 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) PGF-CTERM PF18204.1 KXS98101.1 - 0.51 10.4 3.0 1.3 9.1 3.0 1.7 1 0 0 1 1 1 0 PGF-CTERM motif DUF3149 PF11346.8 KXS98102.1 - 0.2 11.3 0.4 0.44 10.2 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) PGF-CTERM PF18204.1 KXS98102.1 - 0.51 10.4 3.0 1.3 9.1 3.0 1.7 1 0 0 1 1 1 0 PGF-CTERM motif 2OG-FeII_Oxy_3 PF13640.6 KXS98112.1 - 1.5e-08 35.4 0.0 2.7e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Jiv90 PF14901.6 KXS98112.1 - 0.12 12.5 0.3 0.22 11.7 0.3 1.4 1 0 0 1 1 1 0 Cleavage inducing molecular chaperone Importin_rep_4 PF18808.1 KXS98112.1 - 0.46 10.8 2.3 0.82 10.0 2.3 1.3 1 0 0 1 1 1 0 Importin repeat Bax1-I PF01027.20 KXS98113.1 - 1.4e-32 113.2 10.4 2.2e-32 112.6 10.4 1.3 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Pkinase PF00069.25 KXS98114.1 - 2e-19 70.0 0.0 2.9e-19 69.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS98114.1 - 2.2e-10 40.3 0.0 6.2e-09 35.5 0.0 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase Glyco_hydro_38N PF01074.22 KXS98115.1 - 2.2e-85 286.5 1.9 3.6e-85 285.8 1.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 KXS98115.1 - 3.1e-61 207.2 0.8 1.5e-60 204.9 0.2 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 KXS98115.1 - 3e-28 97.8 0.0 9.6e-28 96.2 0.0 1.9 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 KXS98115.1 - 5.1e-09 36.1 0.0 2e-08 34.2 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_57 PF03065.15 KXS98115.1 - 0.00085 18.6 0.2 0.024 13.8 0.0 2.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 57 Tim17 PF02466.19 KXS98116.1 - 0.025 14.9 8.8 0.33 11.3 8.8 2.3 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family XRN_M PF17846.1 KXS98117.1 - 1.5e-144 482.3 0.1 8.9e-143 476.4 0.1 2.3 1 1 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 KXS98117.1 - 2.1e-99 331.9 0.5 6.4e-99 330.3 0.0 1.9 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.23 KXS98117.1 - 0.00033 20.6 4.2 0.0006 19.8 4.2 1.4 1 0 0 1 1 1 1 Zinc knuckle Putative_PNPOx PF01243.20 KXS98118.1 - 0.068 13.4 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Cupin_2 PF07883.11 KXS98119.1 - 1.7e-07 30.8 0.9 2.9e-07 30.1 0.9 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.7 KXS98119.1 - 0.0067 16.2 0.1 0.013 15.3 0.1 1.5 2 0 0 2 2 2 1 Cupin Cupin_1 PF00190.22 KXS98119.1 - 0.028 14.0 0.2 0.035 13.7 0.2 1.2 1 0 0 1 1 1 0 Cupin AraC_binding PF02311.19 KXS98119.1 - 0.029 14.3 0.9 0.045 13.7 0.9 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain Cu-oxidase_2 PF07731.14 KXS98121.1 - 3.8e-41 140.0 9.8 6.4e-40 136.1 1.0 3.2 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KXS98121.1 - 4.6e-41 139.6 4.9 4.6e-41 139.6 4.9 3.6 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.22 KXS98121.1 - 2.2e-33 115.6 0.1 6.8e-33 114.0 0.1 1.9 1 0 0 1 1 1 1 Multicopper oxidase CBM_20 PF00686.19 KXS98121.1 - 5.9e-30 103.0 0.8 1.3e-29 101.9 0.1 2.1 2 0 0 2 2 2 1 Starch binding domain Cu-oxidase_2 PF07731.14 KXS98122.1 - 3.8e-41 140.0 9.8 6.4e-40 136.1 1.0 3.2 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KXS98122.1 - 4.6e-41 139.6 4.9 4.6e-41 139.6 4.9 3.6 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.22 KXS98122.1 - 2.2e-33 115.6 0.1 6.8e-33 114.0 0.1 1.9 1 0 0 1 1 1 1 Multicopper oxidase CBM_20 PF00686.19 KXS98122.1 - 5.9e-30 103.0 0.8 1.3e-29 101.9 0.1 2.1 2 0 0 2 2 2 1 Starch binding domain Uso1_p115_head PF04869.14 KXS98123.1 - 2.5e-63 214.1 0.0 1.5e-62 211.5 0.0 2.4 2 1 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 KXS98123.1 - 2.6e-16 60.1 37.7 2.6e-16 60.1 37.7 8.8 1 1 7 8 8 8 1 Uso1 / p115 like vesicle tethering protein, C terminal region Tropomyosin PF00261.20 KXS98123.1 - 3.9e-08 33.0 42.0 3.9e-08 33.0 42.0 5.0 2 2 2 4 4 4 1 Tropomyosin DHR10 PF18595.1 KXS98123.1 - 0.0056 16.7 28.3 0.0056 16.7 28.3 9.4 2 1 7 9 9 9 2 Designed helical repeat protein 10 domain XhlA PF10779.9 KXS98123.1 - 0.0091 16.2 7.6 0.0091 16.2 7.6 11.9 7 4 7 14 14 14 4 Haemolysin XhlA HCV_NS4b PF01001.19 KXS98123.1 - 0.032 13.8 0.0 0.19 11.3 0.0 2.4 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4b RNB PF00773.19 KXS98124.1 - 1.8e-56 191.9 0.0 2.9e-56 191.2 0.0 1.4 1 0 0 1 1 1 1 RNB domain KH_1 PF00013.29 KXS98124.1 - 0.00015 21.5 0.0 1.6 8.6 0.0 3.4 3 0 0 3 3 3 2 KH domain DUF4042 PF13251.6 KXS98126.1 - 0.085 12.6 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4042) DUF1609 PF07753.11 KXS98127.1 - 0.043 13.3 0.7 0.051 13.1 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1609) NAD_binding_8 PF13450.6 KXS98128.1 - 1.9e-12 47.2 0.2 3.7e-12 46.3 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KXS98128.1 - 2.7e-08 33.5 0.0 9.1e-05 21.9 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase HI0933_like PF03486.14 KXS98128.1 - 7.4e-05 21.6 0.3 0.00016 20.5 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 KXS98128.1 - 8.5e-05 22.3 0.2 0.00016 21.4 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KXS98128.1 - 0.00025 20.5 0.3 0.00059 19.3 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXS98128.1 - 0.0004 19.7 0.1 0.012 14.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXS98128.1 - 0.00048 19.3 0.2 0.00078 18.6 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KXS98128.1 - 0.00074 18.8 0.0 0.0014 17.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 KXS98128.1 - 0.0017 18.8 0.2 0.0078 16.8 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXS98128.1 - 0.023 14.7 0.1 0.06 13.3 0.1 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding GMC_oxred_N PF00732.19 KXS98128.1 - 0.037 13.4 0.0 0.065 12.6 0.0 1.3 1 0 0 1 1 1 0 GMC oxidoreductase Pyr_redox_3 PF13738.6 KXS98128.1 - 0.052 12.8 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AAA_32 PF13654.6 KXS98129.1 - 0.00037 19.4 2.0 0.00041 19.3 2.0 1.1 1 0 0 1 1 1 1 AAA domain EAP30 PF04157.16 KXS98129.1 - 0.00059 19.2 5.6 0.00062 19.1 5.6 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family SKA2 PF16740.5 KXS98129.1 - 0.00069 19.4 12.0 0.0011 18.7 12.0 1.3 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 2 IZUMO PF15005.6 KXS98129.1 - 0.00085 19.9 2.0 0.0011 19.5 2.0 1.2 1 0 0 1 1 1 1 Izumo sperm-egg fusion, Ig domain-associated AIP3 PF03915.13 KXS98129.1 - 0.0014 17.8 5.3 0.0016 17.7 5.3 1.1 1 0 0 1 1 1 1 Actin interacting protein 3 FliD_C PF07195.12 KXS98129.1 - 0.0015 18.0 8.0 0.0022 17.5 8.0 1.2 1 0 0 1 1 1 1 Flagellar hook-associated protein 2 C-terminus Spectrin PF00435.21 KXS98129.1 - 0.0017 18.8 8.9 0.0029 18.1 8.9 1.3 1 0 0 1 1 1 1 Spectrin repeat YojJ PF10372.9 KXS98129.1 - 0.0018 18.3 9.4 0.0047 17.0 8.7 1.9 1 1 1 2 2 2 1 Bacterial membrane-spanning protein N-terminus Prominin PF05478.11 KXS98129.1 - 0.0018 16.3 2.4 0.002 16.2 2.4 1.1 1 0 0 1 1 1 1 Prominin Seryl_tRNA_N PF02403.22 KXS98129.1 - 0.0024 18.1 2.6 0.0034 17.6 2.6 1.3 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.12 KXS98129.1 - 0.0029 17.6 3.3 0.0039 17.2 3.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) YcbB PF08664.10 KXS98129.1 - 0.0029 17.7 2.7 0.0071 16.4 2.6 1.6 2 0 0 2 2 1 1 YcbB domain Dynamin_M PF01031.20 KXS98129.1 - 0.0031 16.8 2.1 0.0036 16.6 2.1 1.1 1 0 0 1 1 1 1 Dynamin central region COG2 PF06148.11 KXS98129.1 - 0.004 17.2 6.6 0.0061 16.7 6.6 1.2 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Gp-FAR-1 PF05823.12 KXS98129.1 - 0.0044 17.4 1.5 0.006 16.9 1.5 1.3 1 0 0 1 1 1 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF3573 PF12097.8 KXS98129.1 - 0.0051 15.7 3.9 0.0055 15.6 3.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3573) Oleosin PF01277.17 KXS98129.1 - 0.0054 16.5 1.4 0.0086 15.8 1.4 1.3 1 0 0 1 1 1 1 Oleosin Allexi_40kDa PF05549.11 KXS98129.1 - 0.0058 16.2 2.8 0.0069 15.9 2.8 1.1 1 0 0 1 1 1 1 Allexivirus 40kDa protein AI-2E_transport PF01594.16 KXS98129.1 - 0.0071 15.5 4.8 0.0087 15.3 4.8 1.2 1 0 0 1 1 1 1 AI-2E family transporter HemX PF04375.14 KXS98129.1 - 0.0081 15.5 11.5 0.011 15.1 11.5 1.3 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase CBP_BcsQ PF06564.12 KXS98129.1 - 0.0085 15.6 3.2 0.011 15.3 3.2 1.1 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ Peptidase_C58 PF03543.14 KXS98129.1 - 0.0094 15.7 3.1 0.012 15.3 3.1 1.2 1 0 0 1 1 1 1 Yersinia/Haemophilus virulence surface antigen Spt20 PF12090.8 KXS98129.1 - 0.012 15.2 12.8 0.014 15.0 12.8 1.1 1 0 0 1 1 1 0 Spt20 family CLZ PF16526.5 KXS98129.1 - 0.012 15.9 5.2 0.025 14.9 5.2 1.5 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FAM76 PF16046.5 KXS98129.1 - 0.015 14.7 3.4 0.018 14.4 3.4 1.1 1 0 0 1 1 1 0 FAM76 protein SKA1 PF07160.12 KXS98129.1 - 0.016 15.1 6.8 0.021 14.7 6.8 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 BLOC1_2 PF10046.9 KXS98129.1 - 0.017 15.4 7.9 0.029 14.7 7.9 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1043 PF06295.12 KXS98129.1 - 0.019 15.0 7.0 0.027 14.5 7.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2203 PF09969.9 KXS98129.1 - 0.02 15.6 1.1 0.027 15.2 1.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DLP_helical PF18709.1 KXS98129.1 - 0.024 13.9 7.7 0.032 13.4 7.7 1.1 1 0 0 1 1 1 0 Dynamin-like helical domain Cortex-I_coil PF09304.10 KXS98129.1 - 0.026 14.7 3.5 0.048 13.9 3.5 1.3 1 0 0 1 1 1 0 Cortexillin I, coiled coil NAP PF00956.18 KXS98129.1 - 0.027 13.6 1.4 0.03 13.5 1.4 1.1 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) AAA_9 PF12781.7 KXS98129.1 - 0.038 13.1 7.8 0.057 12.5 7.8 1.2 1 0 0 1 1 1 0 ATP-binding dynein motor region OmpH PF03938.14 KXS98129.1 - 0.038 14.3 19.0 0.057 13.8 19.0 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Phage_GPO PF05929.11 KXS98129.1 - 0.04 13.5 6.1 0.054 13.1 6.1 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase HEPN_SAV_6107 PF18726.1 KXS98129.1 - 0.041 14.4 0.5 0.062 13.8 0.5 1.3 1 0 0 1 1 1 0 SAV_6107-like HEPN MCU PF04678.13 KXS98129.1 - 0.042 14.0 2.9 0.051 13.7 2.9 1.2 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Ufd2P_core PF10408.9 KXS98129.1 - 0.047 12.3 5.3 0.055 12.1 5.3 1.1 1 0 0 1 1 1 0 Ubiquitin elongating factor core DUF3450 PF11932.8 KXS98129.1 - 0.05 12.9 13.1 0.066 12.5 13.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TFIIA PF03153.13 KXS98129.1 - 0.068 13.2 15.0 0.074 13.0 15.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ACCA PF03255.14 KXS98129.1 - 0.069 13.0 8.2 0.11 12.4 8.2 1.3 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF948 PF06103.11 KXS98129.1 - 0.072 13.4 2.0 0.13 12.6 2.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) KfrA_N PF11740.8 KXS98129.1 - 0.072 13.8 10.5 0.24 12.1 10.8 1.7 2 0 0 2 2 1 0 Plasmid replication region DNA-binding N-term VitK2_biosynth PF02621.14 KXS98129.1 - 0.079 12.5 0.3 0.11 12.1 0.3 1.2 1 0 0 1 1 1 0 Menaquinone biosynthesis FapA PF03961.13 KXS98129.1 - 0.089 11.4 2.6 0.11 11.1 2.6 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF2722 PF10846.8 KXS98129.1 - 0.092 11.7 10.0 0.1 11.5 10.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) RmuC PF02646.16 KXS98129.1 - 0.11 11.5 9.7 0.15 11.2 9.7 1.2 1 0 0 1 1 1 0 RmuC family HAUS6_N PF14661.6 KXS98129.1 - 0.12 11.9 6.0 0.19 11.3 6.0 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Baculo_F PF12259.8 KXS98129.1 - 0.12 10.8 3.5 0.15 10.5 3.5 1.0 1 0 0 1 1 1 0 Baculovirus F protein LMBR1 PF04791.16 KXS98129.1 - 0.13 11.2 0.8 0.13 11.1 0.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Androgen_recep PF02166.16 KXS98129.1 - 0.14 11.0 10.7 0.14 10.9 10.7 1.1 1 0 0 1 1 1 0 Androgen receptor DUF3810 PF12725.7 KXS98129.1 - 0.15 11.4 2.6 0.22 10.9 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) HsbA PF12296.8 KXS98129.1 - 0.17 12.3 8.8 0.17 12.3 7.0 1.7 1 1 1 2 2 2 0 Hydrophobic surface binding protein A ZYG-11_interact PF05884.12 KXS98129.1 - 0.21 11.0 6.1 0.26 10.7 6.1 1.2 1 0 0 1 1 1 0 Interactor of ZYG-11 Remorin_C PF03763.13 KXS98129.1 - 0.22 11.4 7.1 0.32 10.9 7.1 1.1 1 0 0 1 1 1 0 Remorin, C-terminal region zf-CpG_bind_C PF12269.8 KXS98129.1 - 0.23 11.2 6.5 0.3 10.8 6.5 1.1 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain TMPIT PF07851.13 KXS98129.1 - 0.24 10.6 7.2 0.31 10.2 7.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein DASH_Dam1 PF08653.10 KXS98129.1 - 0.24 11.2 5.8 9.6 6.1 1.3 3.3 2 1 0 3 3 3 0 DASH complex subunit Dam1 DUF4199 PF13858.6 KXS98129.1 - 0.26 11.7 9.1 0.39 11.1 9.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) DUF3533 PF12051.8 KXS98129.1 - 0.3 10.0 6.1 0.37 9.6 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Tweety PF04906.13 KXS98129.1 - 0.3 9.7 4.2 0.4 9.3 4.2 1.2 1 0 0 1 1 1 0 Tweety DotU PF09850.9 KXS98129.1 - 0.34 10.6 5.3 0.55 9.9 5.3 1.3 1 0 0 1 1 1 0 Type VI secretion system protein DotU NPV_P10 PF05531.12 KXS98129.1 - 0.49 10.9 13.1 0.8 10.2 12.8 1.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Phage_Mu_Gam PF07352.12 KXS98129.1 - 0.52 10.2 8.0 0.79 9.6 8.0 1.3 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein GBP_C PF02841.14 KXS98129.1 - 0.59 9.5 12.6 0.78 9.1 12.6 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain SseC PF04888.12 KXS98129.1 - 1.1 8.7 16.0 1.6 8.3 16.0 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family DUF1515 PF07439.11 KXS98129.1 - 1.4 9.0 5.3 2.3 8.3 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) DUF4407 PF14362.6 KXS98129.1 - 1.7 7.9 11.1 2.3 7.5 11.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Baculo_PEP_C PF04513.12 KXS98129.1 - 1.9 8.5 16.3 8.2 6.5 16.3 1.9 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus PP_kinase_N PF13089.6 KXS98129.1 - 2.5 8.4 9.0 4.1 7.8 9.0 1.3 1 0 0 1 1 1 0 Polyphosphate kinase N-terminal domain DUF2232 PF09991.9 KXS98129.1 - 3.2 6.8 11.0 4.5 6.4 11.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Snapin_Pallidin PF14712.6 KXS98129.1 - 3.8 8.0 19.7 12 6.5 19.7 1.8 1 1 0 1 1 1 0 Snapin/Pallidin YabA PF06156.13 KXS98129.1 - 4.8 7.9 12.3 2.8 8.6 5.2 2.2 1 1 1 2 2 2 0 Initiation control protein YabA Prefoldin PF02996.17 KXS98129.1 - 5.9 6.8 13.4 10 6.1 13.0 1.6 1 1 0 1 1 1 0 Prefoldin subunit Exonuc_VII_L PF02601.15 KXS98129.1 - 7.5 6.0 15.0 9.1 5.7 15.0 1.3 1 1 0 1 1 1 0 Exonuclease VII, large subunit Spike_torovirin PF17072.5 KXS98129.1 - 9.5 3.2 7.4 11 3.0 7.4 1.0 1 0 0 1 1 1 0 Torovirinae spike glycoprotein zf-C2H2 PF00096.26 KXS98131.1 - 2.4e-12 46.6 16.1 0.0011 19.3 0.8 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS98131.1 - 2.1e-06 28.1 14.0 0.064 14.1 0.3 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger MBD PF01429.19 KXS98131.1 - 0.061 13.0 0.2 0.17 11.6 0.0 1.9 2 0 0 2 2 2 0 Methyl-CpG binding domain zf-H2C2_2 PF13465.6 KXS98131.1 - 0.11 13.0 15.3 1.2 9.7 1.0 4.6 5 0 0 5 5 5 0 Zinc-finger double domain FOXP-CC PF16159.5 KXS98131.1 - 0.35 11.5 3.9 9.2 7.0 0.1 3.1 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-Di19 PF05605.12 KXS98131.1 - 0.52 10.6 9.0 1.1 9.6 1.3 3.3 3 1 1 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_aberr PF17017.5 KXS98131.1 - 2 8.5 6.4 71 3.5 0.5 3.5 2 1 2 4 4 4 0 Aberrant zinc-finger zf-H2C2_5 PF13909.6 KXS98131.1 - 3.2 7.6 11.1 0.61 9.9 3.8 2.8 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.6 KXS98131.1 - 7 6.7 10.2 0.78 9.7 0.3 3.3 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 KXS98131.1 - 8.1 6.9 7.6 2.3 8.6 0.3 3.2 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Telomere_reg-2 PF10193.9 KXS98132.1 - 1.5e-34 118.7 0.0 1.9e-32 111.9 0.0 3.4 3 0 0 3 3 3 1 Telomere length regulation protein HATPase_c PF02518.26 KXS98134.1 - 7.4e-30 103.7 0.2 1.7e-29 102.6 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXS98134.1 - 9.8e-21 74.0 0.1 3.5e-20 72.2 0.0 2.1 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 KXS98134.1 - 2.3e-20 72.4 0.0 7.8e-20 70.7 0.0 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 KXS98134.1 - 2.4e-15 56.6 0.1 9.4e-15 54.7 0.1 2.1 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 KXS98134.1 - 5.1e-14 52.4 0.0 7.6e-05 22.9 0.0 4.6 4 0 0 4 4 4 3 PAS domain PAS_4 PF08448.10 KXS98134.1 - 1.2e-13 51.2 0.0 0.00049 20.3 0.0 4.9 4 1 0 4 4 4 3 PAS fold PAS PF00989.25 KXS98134.1 - 5.8e-08 32.7 0.0 0.095 12.7 0.0 4.2 4 0 0 4 4 4 2 PAS fold PAS_8 PF13188.7 KXS98134.1 - 0.011 15.7 0.0 0.13 12.3 0.0 2.8 2 0 0 2 2 2 0 PAS domain HATPase_c_3 PF13589.6 KXS98134.1 - 0.015 15.2 0.0 0.057 13.2 0.0 2.0 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase APH PF01636.23 KXS98135.1 - 2.4e-17 63.7 0.0 9.2e-17 61.8 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KXS98135.1 - 0.13 11.1 0.0 1 8.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) DPBB_1 PF03330.18 KXS98137.1 - 0.00073 19.8 0.0 0.0016 18.6 0.0 1.5 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KXS98137.1 - 0.12 12.3 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 Barwin family DPBB_1 PF03330.18 KXS98138.1 - 0.00083 19.6 0.0 0.002 18.4 0.0 1.6 1 0 0 1 1 1 1 Lytic transglycolase SRF-TF PF00319.18 KXS98140.1 - 4.7e-09 35.6 0.2 8.8e-09 34.7 0.2 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) SRF-TF PF00319.18 KXS98141.1 - 4.7e-09 35.6 0.2 8.8e-09 34.7 0.2 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) SRF-TF PF00319.18 KXS98142.1 - 4.7e-09 35.6 0.2 8.8e-09 34.7 0.2 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) APC_u14 PF16635.5 KXS98143.1 - 2.8 8.5 6.1 9.4 6.8 1.3 3.0 2 1 0 2 2 2 0 Unstructured region on APC between SAMP and APC_crr ThiF PF00899.21 KXS98144.1 - 7.9e-64 215.3 0.0 1.1e-63 214.9 0.0 1.2 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 KXS98144.1 - 2.7e-27 94.7 0.1 4.7e-27 94.0 0.1 1.4 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 KXS98144.1 - 0.0011 19.1 0.1 0.007 16.4 0.0 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase UAE_UbL PF14732.6 KXS98144.1 - 0.1 13.2 0.1 0.31 11.6 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Ecm33 PF12454.8 KXS98144.1 - 0.13 12.5 2.1 0.28 11.4 2.1 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein PglD_N PF17836.1 KXS98144.1 - 0.16 12.7 0.1 0.45 11.2 0.1 1.8 1 0 0 1 1 1 0 PglD N-terminal domain UBA_e1_thiolCys PF10585.9 KXS98144.1 - 0.16 11.9 2.3 2.9 7.7 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-activating enzyme active site Bac_luciferase PF00296.20 KXS98145.1 - 2.4e-56 191.5 0.1 3.7e-56 190.8 0.1 1.3 1 0 0 1 1 1 1 Luciferase-like monooxygenase DUF3682 PF12446.8 KXS98147.1 - 0.23 11.9 5.2 0.23 11.9 5.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) PRIMA1 PF16101.5 KXS98147.1 - 0.31 11.1 9.2 0.3 11.1 9.2 1.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 KXS98147.1 - 0.38 10.2 9.6 0.42 10.1 9.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 KXS98147.1 - 1.3 9.0 4.3 1.1 9.2 4.3 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator FAD_binding_4 PF01565.23 KXS98148.1 - 2.6e-23 82.3 2.9 5.9e-23 81.1 2.9 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXS98148.1 - 0.0099 16.0 0.1 0.028 14.5 0.1 1.9 1 0 0 1 1 1 1 Berberine and berberine like AAA_32 PF13654.6 KXS98148.1 - 0.085 11.6 0.1 6 5.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain Acyl_CoA_thio PF02551.15 KXS98148.1 - 0.099 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA thioesterase Hormone_3 PF00159.18 KXS98149.1 - 0.0025 17.8 0.4 0.0079 16.3 0.4 1.9 1 0 0 1 1 1 1 Pancreatic hormone peptide Trypsin_2 PF13365.6 KXS98150.1 - 7.6e-25 88.6 0.1 2.1e-24 87.2 0.0 1.7 2 0 0 2 2 2 1 Trypsin-like peptidase domain Peptidase_S46 PF10459.9 KXS98150.1 - 0.01 14.5 0.2 0.023 13.4 0.1 1.5 2 0 0 2 2 2 0 Peptidase S46 Peptidase_S32 PF05579.13 KXS98150.1 - 0.012 14.8 0.2 0.16 11.1 0.0 2.1 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 Peptidase_C4 PF00863.19 KXS98150.1 - 0.2 10.9 0.0 0.45 9.8 0.0 1.5 2 0 0 2 2 2 0 Peptidase family C4 PHD PF00628.29 KXS98152.1 - 0.0004 20.2 9.0 0.0013 18.5 8.9 2.0 1 1 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KXS98152.1 - 0.0075 16.5 2.4 0.014 15.7 2.4 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain SH3_9 PF14604.6 KXS98153.1 - 2.7e-11 43.1 0.0 4.8e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS98153.1 - 5.1e-11 42.0 0.0 1e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KXS98153.1 - 1.6e-05 24.4 0.0 2.9e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Herpes_US12 PF05363.12 KXS98153.1 - 0.84 10.4 3.3 0.42 11.4 0.6 1.9 2 0 0 2 2 2 0 Herpesvirus US12 family MciZ PF13072.6 KXS98161.1 - 0.039 13.8 0.0 0.068 13.0 0.0 1.3 1 0 0 1 1 1 0 Mother cell inhibitor of FtsZ ubiquitin PF00240.23 KXS98162.1 - 4e-07 29.7 0.0 1.1e-06 28.3 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KXS98162.1 - 0.0078 16.0 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 KXS98162.1 - 0.1 12.6 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain TUG-UBL1 PF11470.8 KXS98162.1 - 0.14 12.4 0.0 1.6 9.1 0.0 2.1 2 0 0 2 2 2 0 TUG ubiquitin-like domain CAP PF00188.26 KXS98163.1 - 2.5e-20 73.6 5.1 4.8e-20 72.7 5.1 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ubiquitin PF00240.23 KXS98166.1 - 0.0059 16.3 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family KIND PF16474.5 KXS98166.1 - 0.0067 16.4 0.3 0.01 15.8 0.3 1.2 1 0 0 1 1 1 1 Kinase non-catalytic C-lobe domain TauD PF02668.16 KXS98168.1 - 2.8e-32 112.6 1.3 5.7e-32 111.6 1.3 1.5 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TauD PF02668.16 KXS98169.1 - 1.5e-36 126.5 0.1 2e-36 126.1 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Sugar_tr PF00083.24 KXS98170.1 - 1.9e-99 333.6 18.8 2.4e-99 333.2 18.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS98170.1 - 4.1e-20 72.0 35.4 2.3e-16 59.7 10.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXS98170.1 - 0.00021 19.9 2.1 0.00021 19.9 2.1 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF21 PF01595.20 KXS98170.1 - 0.37 10.5 0.1 0.37 10.5 0.1 2.9 2 1 1 3 3 3 0 Cyclin M transmembrane N-terminal domain Velvet PF11754.8 KXS98171.1 - 3.6e-83 279.3 0.0 3.6e-83 279.3 0.0 2.8 2 1 0 2 2 2 1 Velvet factor OPT PF03169.15 KXS98172.1 - 2e-145 485.9 40.5 2.2e-145 485.7 40.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Astro_capsid_p2 PF16580.5 KXS98173.1 - 0.0022 17.4 0.0 0.0045 16.5 0.0 1.4 2 0 0 2 2 2 1 C-terminal tail of astrovirus capsid projection or spike AA_permease PF00324.21 KXS98174.1 - 9.1e-110 367.5 30.0 1.1e-109 367.2 30.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXS98174.1 - 9.9e-16 57.6 31.9 1.6e-15 56.9 31.9 1.2 1 0 0 1 1 1 1 Amino acid permease Peptidase_M16_C PF05193.21 KXS98175.1 - 2.5e-20 73.2 0.0 7.3e-19 68.5 0.0 2.7 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KXS98175.1 - 2e-07 31.1 0.3 3.9e-06 26.9 0.0 2.4 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) COMMD1_N PF17221.3 KXS98175.1 - 0.045 14.1 0.0 0.15 12.3 0.0 1.9 1 0 0 1 1 1 0 COMMD1 N-terminal domain Glyco_transf_9 PF01075.17 KXS98175.1 - 0.2 11.0 0.7 0.64 9.3 0.7 1.8 1 1 0 1 1 1 0 Glycosyltransferase family 9 (heptosyltransferase) DUF2457 PF10446.9 KXS98175.1 - 2.4 7.2 21.2 4.8 6.2 21.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) M16C_assoc PF08367.11 KXS98175.1 - 6.5 5.8 6.7 75 2.3 6.7 2.2 1 1 0 1 1 1 0 Peptidase M16C associated CDC45 PF02724.14 KXS98175.1 - 8.2 4.6 11.7 16 3.6 11.7 1.4 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_3_Rpc31 PF11705.8 KXS98175.1 - 8.9 6.5 21.5 0.93 9.7 15.8 2.0 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Methyltransf_31 PF13847.6 KXS98176.1 - 0.00084 19.2 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MFS_1 PF07690.16 KXS98177.1 - 3.2e-28 98.7 29.1 5.5e-28 97.9 29.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS98177.1 - 1.6e-09 37.2 8.9 1.6e-09 37.2 8.9 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS98178.1 - 4.1e-33 114.8 34.1 4.1e-33 114.8 34.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily GED PF02212.18 KXS98178.1 - 3.2e-05 24.0 0.1 8.4e-05 22.7 0.1 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain Trp_oprn_chp PF09534.10 KXS98178.1 - 0.77 9.5 4.6 0.57 10.0 1.2 2.3 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) MPC PF03650.13 KXS98179.1 - 7.9e-37 125.8 0.0 9.9e-37 125.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Aminotran_3 PF00202.21 KXS98180.1 - 4.1e-75 252.9 0.0 5.1e-75 252.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Adaptin_N PF01602.20 KXS98181.1 - 4.1e-85 286.3 0.0 7.1e-85 285.5 0.0 1.4 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KXS98181.1 - 8.7e-06 25.9 0.0 0.0028 17.7 0.0 2.6 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KXS98181.1 - 5.8e-05 23.4 4.6 0.39 11.1 0.0 3.8 3 0 0 3 3 3 2 HEAT repeats HEAT PF02985.22 KXS98181.1 - 0.042 14.1 0.0 23 5.6 0.0 4.3 4 0 0 4 4 4 0 HEAT repeat HEAT_EZ PF13513.6 KXS98181.1 - 3.7 8.2 10.3 13 6.4 0.0 5.4 6 1 1 7 7 7 0 HEAT-like repeat RNA_polI_A34 PF08208.11 KXS98181.1 - 8.7 6.4 21.8 19 5.3 21.8 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DIOX_N PF14226.6 KXS98182.1 - 3e-18 66.7 0.0 5.4e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXS98182.1 - 1.5e-14 54.3 0.0 2.8e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NMO PF03060.15 KXS98183.1 - 9.4e-28 97.5 2.5 1e-26 94.1 2.5 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.18 KXS98183.1 - 1.1e-08 34.6 2.9 1.1e-08 34.5 1.3 1.7 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KXS98183.1 - 7.8e-07 28.5 0.1 1.5e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KXS98183.1 - 5.9e-05 22.2 0.1 0.024 13.6 0.2 2.3 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 KXS98183.1 - 0.026 14.0 0.0 0.052 13.0 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein TPR_19 PF14559.6 KXS98184.1 - 3.6e-10 40.2 0.1 1.6e-06 28.5 0.0 3.7 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXS98184.1 - 3e-09 36.3 0.4 1.3e-05 24.8 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KXS98184.1 - 4.4e-09 35.8 0.0 3.6e-06 26.7 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXS98184.1 - 3.7e-08 33.4 0.0 0.00076 19.6 0.0 2.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXS98184.1 - 5.1e-08 33.1 1.7 0.078 13.8 0.0 5.1 1 1 4 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXS98184.1 - 2.8e-06 27.1 0.1 0.00014 21.8 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KXS98184.1 - 4.8e-06 26.9 0.5 0.76 10.5 0.0 4.4 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXS98184.1 - 1.7e-05 24.4 0.0 0.0027 17.3 0.0 3.2 3 1 1 4 4 4 1 TPR repeat TPR_17 PF13431.6 KXS98184.1 - 5.3e-05 23.3 0.1 0.018 15.4 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXS98184.1 - 0.00063 19.6 0.0 0.021 14.8 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXS98184.1 - 0.004 17.8 0.6 0.38 11.5 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat ChAPs PF09295.10 KXS98184.1 - 0.0054 15.8 0.1 0.0075 15.3 0.1 1.3 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_15 PF13429.6 KXS98184.1 - 0.025 13.8 1.6 0.038 13.2 1.6 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXS98184.1 - 0.033 14.5 1.9 0.22 11.9 0.1 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 KXS98184.1 - 0.047 14.0 0.0 0.29 11.5 0.0 2.4 2 1 0 2 2 1 0 Tetratricopeptide repeat Tropomyosin_1 PF12718.7 KXS98185.1 - 0.7 10.0 7.8 4 7.6 0.2 2.2 2 0 0 2 2 2 0 Tropomyosin like RCR PF12273.8 KXS98186.1 - 1.7e-16 61.0 4.3 1.7e-16 61.0 4.3 1.7 2 0 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red Rhabdo_glycop PF00974.18 KXS98186.1 - 0.015 13.8 0.2 0.019 13.4 0.2 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein DUF2207 PF09972.9 KXS98186.1 - 0.025 13.3 0.0 0.029 13.1 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) LapA_dom PF06305.11 KXS98186.1 - 0.047 13.5 1.1 0.066 13.0 1.1 1.1 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain SKG6 PF08693.10 KXS98186.1 - 0.38 10.2 4.3 0.57 9.6 4.3 1.2 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Syntaxin-6_N PF09177.11 KXS98187.1 - 0.037 14.6 1.0 0.037 14.6 1.0 1.6 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Symplekin_C PF12295.8 KXS98187.1 - 0.056 13.5 0.2 0.073 13.2 0.2 1.3 1 0 0 1 1 1 0 Symplekin tight junction protein C terminal DUF1664 PF07889.12 KXS98187.1 - 0.25 11.4 2.5 0.52 10.4 1.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) zf-RING_2 PF13639.6 KXS98188.1 - 1.6e-08 34.7 11.3 3.8e-08 33.5 11.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KXS98188.1 - 5.1e-07 29.5 8.5 9.7e-07 28.6 8.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXS98188.1 - 1.3e-06 28.2 10.5 3.1e-06 26.9 10.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS98188.1 - 1.7e-06 27.8 9.8 3.4e-06 26.8 9.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXS98188.1 - 3.8e-06 26.8 7.3 8.9e-06 25.6 7.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KXS98188.1 - 5.1e-06 26.3 9.6 1.1e-05 25.3 9.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KXS98188.1 - 6.3e-05 23.2 10.6 0.00025 21.3 10.6 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KXS98188.1 - 8e-05 22.4 8.2 0.00016 21.5 8.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KXS98188.1 - 0.00029 20.9 8.1 0.00072 19.7 8.1 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 KXS98188.1 - 0.0071 16.4 1.9 0.016 15.2 1.9 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 KXS98188.1 - 0.038 14.1 5.8 0.086 13.0 5.8 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 KXS98188.1 - 0.082 12.7 6.1 0.27 11.0 6.1 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF1272 PF06906.11 KXS98188.1 - 0.42 10.7 6.6 1 9.5 6.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zinc-ribbons_6 PF07191.12 KXS98188.1 - 0.82 9.7 7.0 1.8 8.6 7.0 1.6 1 0 0 1 1 1 0 zinc-ribbons zf-P11 PF03854.14 KXS98188.1 - 1.3 8.7 7.2 0.94 9.2 2.8 2.4 1 1 1 2 2 2 0 P-11 zinc finger APG5 PF04106.12 KXS98189.1 - 3.7e-65 219.7 0.0 4.7e-65 219.4 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 Peptidase_M1 PF01433.20 KXS98190.1 - 4.4e-75 252.0 0.1 7e-75 251.3 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 KXS98190.1 - 6.2e-58 196.8 0.1 8.7e-58 196.3 0.1 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 KXS98190.1 - 5.2e-41 140.9 0.0 1e-40 139.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Cu2_monoox_C PF03712.15 KXS98197.1 - 1.8e-26 92.6 0.0 3.4e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain CDH-cyt PF16010.5 KXS98197.1 - 1.9e-25 89.6 10.2 4.3e-23 82.0 5.5 3.3 3 0 0 3 3 3 2 Cytochrome domain of cellobiose dehydrogenase Cu2_monooxygen PF01082.20 KXS98197.1 - 2.3e-23 82.9 0.1 4.7e-23 81.8 0.1 1.6 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain DOMON PF03351.17 KXS98197.1 - 2.6e-17 63.2 5.9 1.4e-10 41.4 0.4 2.7 2 0 0 2 2 2 2 DOMON domain Cytochrom_B561 PF03188.16 KXS98197.1 - 1.5 9.0 10.5 3.2 7.9 10.5 1.5 1 0 0 1 1 1 0 Eukaryotic cytochrome b561 GDPD PF03009.17 KXS98198.1 - 8.7e-70 235.4 0.0 9.1e-69 232.1 0.0 2.3 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 KXS98198.1 - 1.2e-33 115.5 3.3 6.8e-19 68.3 0.3 3.9 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS98198.1 - 2.1e-26 91.9 4.5 2.3e-08 34.4 0.1 5.4 5 0 0 5 5 5 4 Ankyrin repeats (many copies) SPX PF03105.19 KXS98198.1 - 1.2e-23 84.7 6.6 3.5e-12 46.9 0.1 4.0 1 1 2 3 3 3 3 SPX domain Ank_3 PF13606.6 KXS98198.1 - 4.4e-19 66.6 4.7 0.00023 21.3 0.1 7.7 8 0 0 8 8 8 4 Ankyrin repeat Ank PF00023.30 KXS98198.1 - 6.1e-17 61.2 7.8 0.00021 21.6 0.1 6.0 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 KXS98198.1 - 8.5e-17 61.0 0.8 0.00034 20.8 0.0 5.5 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Env-gp36 PF09590.10 KXS98198.1 - 0.2 10.1 0.0 0.3 9.5 0.0 1.1 1 0 0 1 1 1 0 Lentivirus surface glycoprotein Bac_luciferase PF00296.20 KXS98199.1 - 7.3e-52 176.7 0.3 9.3e-52 176.4 0.3 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Bac_luciferase PF00296.20 KXS98200.1 - 7.3e-52 176.7 0.3 9.3e-52 176.4 0.3 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase SET PF00856.28 KXS98201.1 - 1.6e-07 31.9 0.2 1.6e-07 31.9 0.2 2.3 2 1 0 2 2 2 1 SET domain Sec66 PF09802.9 KXS98201.1 - 0.059 12.9 2.8 0.15 11.6 2.7 1.8 1 1 0 1 1 1 0 Preprotein translocase subunit Sec66 DUF2072 PF09845.9 KXS98201.1 - 0.083 13.1 0.8 0.78 10.0 0.0 2.3 2 0 0 2 2 2 0 Zn-ribbon containing protein SH3_9 PF14604.6 KXS98202.1 - 4.8e-06 26.3 0.0 1.1e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS98202.1 - 5.4e-05 22.7 0.1 0.00012 21.6 0.1 1.5 1 0 0 1 1 1 1 SH3 domain DUF4690 PF15756.5 KXS98202.1 - 0.021 15.4 0.5 0.12 13.0 0.5 2.3 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Mid2 PF04478.12 KXS98202.1 - 0.081 12.7 0.2 0.17 11.7 0.2 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Podoplanin PF05808.11 KXS98202.1 - 0.092 12.8 0.2 0.092 12.8 0.2 2.1 2 0 0 2 2 2 0 Podoplanin Clathrin PF00637.20 KXS98203.1 - 3.4e-20 72.4 3.0 1.3e-19 70.5 1.2 2.5 3 0 0 3 3 3 1 Region in Clathrin and VPS VPS11_C PF12451.8 KXS98203.1 - 4.1e-15 55.7 0.0 1.1e-14 54.3 0.0 1.8 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 KXS98203.1 - 1.9e-06 27.8 2.8 4.5e-06 26.6 2.8 1.7 1 0 0 1 1 1 1 Zinc-finger TPR_11 PF13414.6 KXS98203.1 - 0.00033 20.3 1.5 0.0007 19.2 0.1 2.2 2 0 0 2 2 2 1 TPR repeat Utp13 PF08625.11 KXS98203.1 - 0.0057 16.6 0.6 2.1 8.2 0.0 2.8 2 0 0 2 2 2 1 Utp13 specific WD40 associated domain PHD PF00628.29 KXS98203.1 - 0.009 15.9 2.5 0.019 14.9 2.5 1.6 1 0 0 1 1 1 1 PHD-finger zf-RING_5 PF14634.6 KXS98203.1 - 0.012 15.5 3.1 0.027 14.4 3.1 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXS98203.1 - 0.023 14.7 1.5 0.023 14.7 1.5 2.1 2 1 0 2 2 2 0 RING-type zinc-finger TPR_14 PF13428.6 KXS98203.1 - 0.025 15.4 3.1 1.4 9.9 0.0 3.7 3 1 1 4 4 3 0 Tetratricopeptide repeat zf-RING_2 PF13639.6 KXS98203.1 - 0.028 14.7 4.6 0.061 13.7 4.6 1.6 1 0 0 1 1 1 0 Ring finger domain MCM_N PF14551.6 KXS98203.1 - 0.043 14.4 7.7 0.16 12.5 1.1 3.6 3 1 0 3 3 3 0 MCM N-terminal domain zf-C3HC4_2 PF13923.6 KXS98203.1 - 0.062 13.2 7.5 0.23 11.3 7.5 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_2 PF07719.17 KXS98203.1 - 0.072 13.2 3.5 0.51 10.6 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-C3HC4 PF00097.25 KXS98203.1 - 0.33 10.9 2.7 0.8 9.6 2.7 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ANAPC3 PF12895.7 KXS98203.1 - 0.35 11.1 7.6 11 6.3 0.2 4.1 2 2 2 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 zf-rbx1 PF12678.7 KXS98203.1 - 1.8 8.9 5.1 4.7 7.6 5.1 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger domain TPR_1 PF00515.28 KXS98203.1 - 1.9 8.4 5.4 6 6.9 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat His_Phos_2 PF00328.22 KXS98204.1 - 4.6e-06 26.2 0.2 0.00031 20.2 0.0 2.3 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) DUF2613 PF11021.8 KXS98204.1 - 0.52 10.5 3.3 0.92 9.7 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2613) PEMT PF04191.13 KXS98205.1 - 2.5e-55 185.4 11.3 4.6e-36 123.4 2.3 3.5 4 0 0 4 4 4 2 Phospholipid methyltransferase HECW_N PF16562.5 KXS98205.1 - 0.0014 18.4 0.0 0.0038 17.0 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 SKICH PF17751.1 KXS98205.1 - 0.0052 17.3 0.1 0.033 14.7 0.1 2.2 1 1 0 1 1 1 1 SKICH domain Mpv17_PMP22 PF04117.12 KXS98205.1 - 0.28 11.5 7.3 0.15 12.3 3.9 2.4 2 0 0 2 2 2 0 Mpv17 / PMP22 family WD40 PF00400.32 KXS98206.1 - 7e-11 42.5 11.9 0.0024 18.6 0.0 5.2 4 1 1 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS98206.1 - 2.5e-05 24.5 0.0 2.3 8.6 0.0 4.4 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain SGL PF08450.12 KXS98206.1 - 0.00047 19.8 0.1 2.7 7.5 0.0 3.6 1 1 2 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region eIF2A PF08662.11 KXS98206.1 - 0.0012 18.8 0.0 0.62 9.9 0.0 2.5 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ceramidase PF05875.12 KXS98207.1 - 9e-75 251.5 4.2 1.1e-74 251.2 4.2 1.0 1 0 0 1 1 1 1 Ceramidase Bac_small_YrzI PF09501.10 KXS98207.1 - 0.02 15.0 1.4 0.057 13.6 1.4 1.8 1 0 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) DUF92 PF01940.16 KXS98207.1 - 0.052 13.0 0.1 0.097 12.1 0.1 1.4 1 0 0 1 1 1 0 Integral membrane protein DUF92 DUF2243 PF10002.9 KXS98207.1 - 0.1 12.7 0.9 0.31 11.1 0.0 2.1 2 1 0 2 2 2 0 Predicted membrane protein (DUF2243) Spore_YabQ PF09578.10 KXS98207.1 - 0.1 12.8 3.0 0.66 10.2 0.1 2.7 2 0 0 2 2 2 0 Spore cortex protein YabQ (Spore_YabQ) TctB PF07331.11 KXS98207.1 - 0.29 11.4 2.7 0.64 10.3 0.2 2.4 1 1 2 3 3 3 0 Tripartite tricarboxylate transporter TctB family DDHD PF02862.17 KXS98208.1 - 3.9e-21 76.2 0.2 3.2e-13 50.4 0.0 2.7 2 1 1 3 3 3 2 DDHD domain Caldesmon PF02029.15 KXS98209.1 - 0.00048 19.0 4.1 0.00074 18.4 4.1 1.2 1 0 0 1 1 1 1 Caldesmon Med19 PF10278.9 KXS98209.1 - 0.061 13.2 3.5 0.11 12.4 3.5 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Peptidase_S49_N PF08496.10 KXS98209.1 - 0.073 13.1 0.5 0.11 12.6 0.5 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CCDC106 PF15794.5 KXS98209.1 - 0.27 10.9 9.3 0.029 14.1 4.1 1.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 SR-25 PF10500.9 KXS98209.1 - 0.35 10.4 16.2 0.45 10.1 16.2 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein CDC45 PF02724.14 KXS98209.1 - 0.66 8.2 6.1 0.97 7.6 6.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 KXS98209.1 - 4.6 5.9 6.6 5.2 5.7 6.6 1.1 1 0 0 1 1 1 0 Presenilin ATP_bind_1 PF03029.17 KXS98210.1 - 2e-58 198.1 0.0 2.5e-58 197.7 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 KXS98210.1 - 0.013 15.6 0.0 0.089 12.9 0.0 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase MeaB PF03308.16 KXS98210.1 - 0.023 13.7 0.0 0.058 12.4 0.0 1.6 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_28 PF13521.6 KXS98210.1 - 0.024 14.9 2.4 0.052 13.8 0.0 2.7 2 1 1 3 3 3 0 AAA domain AAA_22 PF13401.6 KXS98210.1 - 0.029 14.7 0.0 0.11 12.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.18 KXS98210.1 - 0.038 13.5 0.1 8 6.0 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_30 PF13604.6 KXS98210.1 - 0.045 13.5 0.1 0.16 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain 6PF2K PF01591.18 KXS98210.1 - 0.045 13.0 0.0 0.072 12.4 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase RsgA_GTPase PF03193.16 KXS98210.1 - 0.055 13.4 0.0 0.35 10.8 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_33 PF13671.6 KXS98210.1 - 0.072 13.3 0.0 0.26 11.5 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KXS98210.1 - 0.074 13.5 0.7 0.23 11.9 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KXS98210.1 - 0.081 13.5 1.3 0.23 12.0 0.1 2.4 2 2 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KXS98210.1 - 0.14 12.7 0.0 0.47 11.0 0.0 1.9 2 0 0 2 2 2 0 ABC transporter RuvB_N PF05496.12 KXS98210.1 - 0.16 11.7 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KXS98210.1 - 0.32 11.3 2.6 1 9.7 0.2 2.6 1 1 1 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 KXS98210.1 - 4.7 6.7 8.9 5 6.7 0.9 3.9 3 1 0 3 3 3 0 AAA domain Glyco_hydro_43 PF04616.14 KXS98212.1 - 1.3e-19 70.7 0.2 1.7e-19 70.3 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Peptidase_S10 PF00450.22 KXS98213.1 - 2.9e-71 241.1 0.1 3.7e-71 240.7 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase adh_short_C2 PF13561.6 KXS98214.1 - 7.2e-52 176.3 0.0 8.8e-52 176.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS98214.1 - 1.9e-45 154.7 0.0 2.4e-45 154.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS98214.1 - 1e-13 51.6 0.0 1.4e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS98214.1 - 2.2e-05 24.1 0.1 0.00022 20.8 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KXS98214.1 - 0.011 14.9 0.1 0.016 14.4 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KXS98214.1 - 0.012 15.0 0.1 0.041 13.3 0.0 1.7 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KXS98214.1 - 0.097 11.7 0.1 0.13 11.3 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Thioesterase PF00975.20 KXS98215.1 - 4.2e-24 85.9 0.0 9.4e-24 84.8 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 KXS98215.1 - 0.0077 16.9 0.3 0.028 15.0 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family PP-binding PF00550.25 KXS98215.1 - 0.0081 16.5 0.0 0.015 15.7 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Acyl_transf_3 PF01757.22 KXS98216.1 - 1.8e-25 89.7 32.1 3.6e-25 88.7 32.1 1.5 1 0 0 1 1 1 1 Acyltransferase family LSM PF01423.22 KXS98217.1 - 8.2e-20 70.3 0.1 9.3e-20 70.1 0.1 1.1 1 0 0 1 1 1 1 LSM domain AT_hook PF02178.19 KXS98218.1 - 0.31 11.0 8.1 0.24 11.4 3.9 3.3 2 0 0 2 2 2 0 AT hook motif LSM PF01423.22 KXS98219.1 - 8.2e-20 70.3 0.1 9.3e-20 70.1 0.1 1.1 1 0 0 1 1 1 1 LSM domain FAD_binding_3 PF01494.19 KXS98221.1 - 5.3e-18 65.4 0.9 2.9e-17 62.9 0.9 2.0 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KXS98221.1 - 4.7e-06 25.6 0.1 0.008 14.9 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 KXS98221.1 - 0.0001 21.5 0.6 0.00095 18.3 0.1 2.1 1 1 1 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KXS98221.1 - 0.00013 21.3 0.1 0.092 12.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXS98221.1 - 0.00087 18.7 0.7 0.003 17.0 0.2 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXS98221.1 - 0.0019 17.5 0.0 0.026 13.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXS98221.1 - 0.0034 17.0 0.2 2.5 7.6 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXS98221.1 - 0.035 14.4 0.0 0.084 13.1 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXS98221.1 - 0.05 14.2 0.0 2.3 8.8 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXS98221.1 - 0.091 11.8 0.6 0.29 10.2 0.6 1.7 1 1 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 KXS98221.1 - 0.16 10.8 2.0 9.4 5.0 0.1 2.7 2 1 1 3 3 3 0 Tryptophan halogenase CDC27 PF09507.10 KXS98222.1 - 7.3e-86 289.2 22.4 9.9e-86 288.8 22.4 1.2 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 Mannosyl_trans3 PF11051.8 KXS98222.1 - 0.017 14.5 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative Hemerythrin PF01814.23 KXS98223.1 - 0.0078 16.8 0.0 0.011 16.3 0.0 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain UBZ_FAAP20 PF15750.5 KXS98223.1 - 0.18 11.8 0.0 0.39 10.7 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-binding zinc-finger GMC_oxred_N PF00732.19 KXS98224.1 - 3.6e-73 246.5 0.0 4.7e-73 246.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXS98224.1 - 2.7e-41 141.4 0.2 4.9e-41 140.6 0.2 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KXS98224.1 - 9.2e-05 21.7 0.0 0.00014 21.0 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KXS98224.1 - 0.00054 20.1 0.0 0.0015 18.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXS98224.1 - 0.00083 19.0 0.1 0.0023 17.6 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXS98224.1 - 0.0017 17.6 0.0 0.0033 16.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KXS98224.1 - 0.0025 17.1 0.0 0.0048 16.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXS98224.1 - 0.0029 16.7 0.0 0.0094 15.1 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 KXS98224.1 - 0.0087 15.4 0.2 0.15 11.3 0.1 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXS98224.1 - 0.017 13.8 0.0 0.028 13.1 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein TrkA_N PF02254.18 KXS98224.1 - 0.032 14.5 0.0 0.07 13.4 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain PRiA4_ORF3 PF07929.11 KXS98225.1 - 2.1e-06 27.6 0.0 2.9e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein Citrate_bind PF16114.5 KXS98227.1 - 2.7e-88 294.1 0.0 3.7e-88 293.7 0.0 1.2 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding ATP-grasp_2 PF08442.10 KXS98227.1 - 6.3e-07 29.2 0.0 9.8e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Polysacc_deac_1 PF01522.21 KXS98227.1 - 0.12 12.3 0.0 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 Polysaccharide deacetylase Fip1 PF05182.13 KXS98229.1 - 1.3e-18 66.2 0.9 2.3e-18 65.4 0.9 1.4 1 0 0 1 1 1 1 Fip1 motif TFIIF_alpha PF05793.12 KXS98229.1 - 0.023 13.3 11.0 0.032 12.8 11.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) YL1 PF05764.13 KXS98229.1 - 0.11 12.6 8.6 0.14 12.2 8.6 1.3 1 0 0 1 1 1 0 YL1 nuclear protein DLIC PF05783.11 KXS98229.1 - 1.2 7.8 8.1 0.032 13.1 0.6 1.9 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) CDC45 PF02724.14 KXS98229.1 - 8.8 4.5 8.4 12 4.0 8.4 1.1 1 0 0 1 1 1 0 CDC45-like protein ABC2_membrane PF01061.24 KXS98230.1 - 0.55 9.6 11.8 5.7 6.3 11.8 2.0 1 1 0 1 1 1 0 ABC-2 type transporter Citrate_synt PF00285.21 KXS98231.1 - 2.2e-21 76.4 0.0 4.2e-18 65.5 0.0 2.9 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain CoA_binding PF02629.19 KXS98231.1 - 1.4e-17 64.2 0.0 3.2e-17 63.0 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain Ligase_CoA PF00549.19 KXS98231.1 - 8.8e-15 54.8 0.1 1.8e-14 53.8 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KXS98231.1 - 2.8e-06 27.2 0.1 7.3e-05 22.6 0.0 2.4 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain MFS_1 PF07690.16 KXS98232.1 - 6.3e-20 71.4 57.4 8.7e-18 64.4 56.0 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily Peroxidase_2 PF01328.17 KXS98233.1 - 8.7e-15 55.7 0.0 1.2e-14 55.3 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 Peroxidase_2 PF01328.17 KXS98235.1 - 3.4e-18 66.8 0.0 3.7e-13 50.4 0.0 2.3 2 0 0 2 2 2 2 Peroxidase, family 2 Sugar_tr PF00083.24 KXS98241.1 - 2.2e-71 241.1 17.8 2.6e-71 240.9 17.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS98241.1 - 5.9e-27 94.5 54.3 5.1e-23 81.6 26.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXS98241.1 - 3.4e-07 29.2 20.0 1.1e-06 27.5 3.9 3.0 3 0 0 3 3 3 2 MFS/sugar transport protein DUF4602 PF15375.6 KXS98242.1 - 3.3e-15 56.6 14.8 8.1e-15 55.3 14.8 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4602) UPF0370 PF13980.6 KXS98245.1 - 0.023 14.7 0.0 0.45 10.6 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0370) UPF0370 PF13980.6 KXS98246.1 - 0.023 14.7 0.0 0.45 10.6 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0370) GCP_N_terminal PF17681.1 KXS98247.1 - 6e-19 68.8 0.0 9.6e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KXS98247.1 - 9.8e-12 45.0 0.7 2.1e-11 43.8 0.7 1.6 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP5-Mod21 PF14609.6 KXS98247.1 - 0.00026 19.5 0.0 0.0025 16.3 0.0 2.1 1 1 0 1 1 1 1 gamma-Tubulin ring complex non-core subunit mod21 Death PF00531.22 KXS98247.1 - 0.019 15.2 0.2 0.15 12.2 0.1 2.5 2 0 0 2 2 2 0 Death domain Med26 PF08711.11 KXS98247.1 - 0.17 11.9 0.1 0.76 9.8 0.0 2.1 2 0 0 2 2 2 0 TFIIS helical bundle-like domain tRNA-synt_1c PF00749.21 KXS98248.1 - 3.1e-110 368.0 0.2 4.5e-110 367.4 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KXS98248.1 - 5.5e-34 117.5 3.1 5.5e-34 117.5 3.1 2.0 2 1 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.6 KXS98248.1 - 0.0034 17.6 0.3 0.65 10.2 0.0 2.7 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.19 KXS98248.1 - 0.017 14.5 1.4 0.063 12.6 1.4 1.9 1 1 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain CoaE PF01121.20 KXS98249.1 - 1.1e-42 145.8 0.0 6.3e-42 143.3 0.0 1.9 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_33 PF13671.6 KXS98249.1 - 0.00024 21.3 0.0 0.0041 17.3 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXS98249.1 - 0.01 16.4 0.1 0.56 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain Hid1 PF12722.7 KXS98250.1 - 1.2 7.2 7.0 1.3 7.1 7.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PAD_porph PF04371.15 KXS98251.1 - 5.9e-44 150.6 0.0 6.5e-44 150.5 0.0 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase Amidinotransf PF02274.17 KXS98251.1 - 0.052 12.6 0.0 0.057 12.5 0.0 1.3 1 1 0 1 1 1 0 Amidinotransferase Pepsin-I3 PF06394.13 KXS98251.1 - 0.18 12.0 0.0 0.29 11.4 0.0 1.3 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain DUF953 PF06110.11 KXS98252.1 - 1.4e-15 57.0 0.2 2.4e-15 56.2 0.1 1.4 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Sugar_tr PF00083.24 KXS98253.1 - 1.9e-117 392.9 25.6 2.3e-117 392.6 25.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS98253.1 - 9.9e-25 87.2 34.2 5.9e-22 78.1 20.4 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily AA_permease PF00324.21 KXS98254.1 - 7.3e-76 255.7 30.6 9e-76 255.4 30.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXS98254.1 - 2.9e-24 85.7 37.2 3.7e-24 85.4 37.2 1.1 1 0 0 1 1 1 1 Amino acid permease Pkinase PF00069.25 KXS98255.1 - 1.8e-12 47.2 0.0 3.4e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS98255.1 - 3.8e-09 36.2 0.0 6.4e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXS98255.1 - 0.012 14.9 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Syntaxin-6_N PF09177.11 KXS98256.1 - 1.3e-23 83.4 0.3 1.3e-22 80.2 0.0 2.2 2 0 0 2 2 2 1 Syntaxin 6, N-terminal ApoL PF05461.11 KXS98256.1 - 0.0074 15.6 0.7 0.046 13.0 0.0 2.1 2 0 0 2 2 2 1 Apolipoprotein L DUF2207 PF09972.9 KXS98256.1 - 0.062 12.0 0.0 1.1 7.9 0.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Laminin_II PF06009.12 KXS98256.1 - 0.085 12.9 3.0 5.3 7.0 0.2 2.4 2 1 0 2 2 2 0 Laminin Domain II WXG100 PF06013.12 KXS98256.1 - 0.12 12.7 5.4 10 6.4 0.6 3.4 3 1 0 3 3 3 0 Proteins of 100 residues with WXG DegS PF05384.11 KXS98256.1 - 0.14 11.6 1.9 15 5.0 0.0 2.8 3 0 0 3 3 3 0 Sensor protein DegS ArAE_2_N PF10337.9 KXS98256.1 - 0.17 10.9 0.1 0.36 9.8 0.1 1.3 1 1 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal DUF1664 PF07889.12 KXS98256.1 - 0.19 11.8 1.4 11 6.1 0.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) GCIP PF13324.6 KXS98256.1 - 0.39 10.3 5.6 0.77 9.3 2.6 2.1 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting Myosin_tail_1 PF01576.19 KXS98256.1 - 0.4 8.4 5.8 0.97 7.1 0.1 2.0 2 0 0 2 2 2 0 Myosin tail DUF883 PF05957.13 KXS98256.1 - 2 9.1 8.3 1.1 9.8 0.7 3.2 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) Syntaxin-6_N PF09177.11 KXS98257.1 - 1.3e-23 83.4 0.3 1.3e-22 80.2 0.0 2.2 2 0 0 2 2 2 1 Syntaxin 6, N-terminal ApoL PF05461.11 KXS98257.1 - 0.0074 15.6 0.7 0.046 13.0 0.0 2.1 2 0 0 2 2 2 1 Apolipoprotein L DUF2207 PF09972.9 KXS98257.1 - 0.062 12.0 0.0 1.1 7.9 0.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Laminin_II PF06009.12 KXS98257.1 - 0.085 12.9 3.0 5.3 7.0 0.2 2.4 2 1 0 2 2 2 0 Laminin Domain II WXG100 PF06013.12 KXS98257.1 - 0.12 12.7 5.4 10 6.4 0.6 3.4 3 1 0 3 3 3 0 Proteins of 100 residues with WXG DegS PF05384.11 KXS98257.1 - 0.14 11.6 1.9 15 5.0 0.0 2.8 3 0 0 3 3 3 0 Sensor protein DegS ArAE_2_N PF10337.9 KXS98257.1 - 0.17 10.9 0.1 0.36 9.8 0.1 1.3 1 1 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal DUF1664 PF07889.12 KXS98257.1 - 0.19 11.8 1.4 11 6.1 0.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) GCIP PF13324.6 KXS98257.1 - 0.39 10.3 5.6 0.77 9.3 2.6 2.1 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting Myosin_tail_1 PF01576.19 KXS98257.1 - 0.4 8.4 5.8 0.97 7.1 0.1 2.0 2 0 0 2 2 2 0 Myosin tail DUF883 PF05957.13 KXS98257.1 - 2 9.1 8.3 1.1 9.8 0.7 3.2 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) Arylsulfotran_2 PF14269.6 KXS98258.1 - 4.9e-47 160.7 0.8 8.3e-47 160.0 0.8 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KXS98258.1 - 1.9e-16 60.0 1.5 8.5e-15 54.5 1.5 2.2 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) LIP PF03583.14 KXS98259.1 - 0.0011 18.4 0.0 0.0014 18.0 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase PLDc_N PF13396.6 KXS98259.1 - 0.028 14.4 0.0 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal DUF89 PF01937.19 KXS98260.1 - 1.1e-130 435.7 0.2 1.3e-130 435.5 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Arylsulfotran_2 PF14269.6 KXS98261.1 - 4.9e-47 160.7 0.8 8.3e-47 160.0 0.8 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KXS98261.1 - 1.9e-16 60.0 1.5 8.5e-15 54.5 1.5 2.2 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) LIP PF03583.14 KXS98262.1 - 0.0011 18.4 0.0 0.0014 18.0 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase PLDc_N PF13396.6 KXS98262.1 - 0.028 14.4 0.0 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal DUF89 PF01937.19 KXS98263.1 - 1.1e-130 435.7 0.2 1.3e-130 435.5 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Arylsulfotran_2 PF14269.6 KXS98264.1 - 4.9e-47 160.7 0.8 8.3e-47 160.0 0.8 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KXS98264.1 - 1.9e-16 60.0 1.5 8.5e-15 54.5 1.5 2.2 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) LIP PF03583.14 KXS98265.1 - 0.0011 18.4 0.0 0.0014 18.0 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase PLDc_N PF13396.6 KXS98265.1 - 0.028 14.4 0.0 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal DUF89 PF01937.19 KXS98266.1 - 1.1e-130 435.7 0.2 1.3e-130 435.5 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 LIP PF03583.14 KXS98267.1 - 0.0011 18.4 0.0 0.0014 18.0 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase PLDc_N PF13396.6 KXS98267.1 - 0.028 14.4 0.0 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal DUF89 PF01937.19 KXS98268.1 - 1.1e-130 435.7 0.2 1.3e-130 435.5 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 His_biosynth PF00977.21 KXS98269.1 - 2.1e-32 112.4 0.0 2.8e-32 112.0 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 KXS98269.1 - 0.19 11.1 0.0 0.28 10.6 0.0 1.2 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Thioredoxin PF00085.20 KXS98271.1 - 0.00025 21.0 0.0 0.00039 20.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin DUF2383 PF09537.10 KXS98271.1 - 0.017 15.4 0.6 0.042 14.2 0.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF2383) HET PF06985.11 KXS98272.1 - 1e-27 97.3 0.1 2.4e-27 96.1 0.1 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CFEM PF05730.11 KXS98295.1 - 7.9e-13 48.3 11.4 1.3e-12 47.6 11.4 1.4 1 0 0 1 1 1 1 CFEM domain DUF2721 PF11026.8 KXS98295.1 - 0.25 11.2 3.9 0.18 11.7 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) DUF3671 PF12420.8 KXS98295.1 - 0.33 11.0 3.7 3.5 7.7 3.2 2.4 1 1 0 1 1 1 0 Protein of unknown function CFEM PF05730.11 KXS98296.1 - 7.9e-13 48.3 11.4 1.3e-12 47.6 11.4 1.4 1 0 0 1 1 1 1 CFEM domain DUF2721 PF11026.8 KXS98296.1 - 0.25 11.2 3.9 0.18 11.7 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) DUF3671 PF12420.8 KXS98296.1 - 0.33 11.0 3.7 3.5 7.7 3.2 2.4 1 1 0 1 1 1 0 Protein of unknown function CFEM PF05730.11 KXS98297.1 - 6.9e-13 48.5 11.4 1.2e-12 47.8 11.4 1.4 1 0 0 1 1 1 1 CFEM domain DUF3671 PF12420.8 KXS98297.1 - 2.1 8.5 6.8 6.6 6.9 4.4 2.6 1 1 0 1 1 1 0 Protein of unknown function CFEM PF05730.11 KXS98298.1 - 7.6e-13 48.4 11.4 1.3e-12 47.7 11.4 1.4 1 0 0 1 1 1 1 CFEM domain DUF3671 PF12420.8 KXS98298.1 - 1.2 9.2 5.8 4.8 7.3 3.8 2.5 1 1 0 1 1 1 0 Protein of unknown function CFEM PF05730.11 KXS98299.1 - 6.9e-13 48.5 11.4 1.2e-12 47.8 11.4 1.4 1 0 0 1 1 1 1 CFEM domain DUF3671 PF12420.8 KXS98299.1 - 2.1 8.5 6.8 6.6 6.9 4.4 2.6 1 1 0 1 1 1 0 Protein of unknown function MaoC_dehydratas PF01575.19 KXS98300.1 - 9.1e-10 38.2 0.0 6e-09 35.5 0.0 2.0 1 1 0 1 1 1 1 MaoC like domain DAO PF01266.24 KXS98301.1 - 4.8e-37 128.4 3.9 5.5e-37 128.2 3.9 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXS98301.1 - 0.0022 17.3 1.6 0.0086 15.3 0.1 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 KXS98301.1 - 0.0023 17.2 0.1 0.0046 16.2 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXS98301.1 - 0.0027 17.9 1.0 0.0071 16.6 0.3 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KXS98301.1 - 0.0046 16.2 0.4 0.27 10.4 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain DUF1188 PF06690.11 KXS98301.1 - 0.0052 16.4 0.1 2 7.9 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1188) FAD_binding_2 PF00890.24 KXS98301.1 - 0.0081 15.3 0.0 0.016 14.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KXS98301.1 - 0.013 16.0 0.4 0.034 14.7 0.1 1.9 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 KXS98301.1 - 0.026 14.1 0.2 0.041 13.5 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Glu_dehyd_C PF16912.5 KXS98301.1 - 0.039 13.4 0.1 2.4 7.6 0.0 2.2 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus NAD_binding_7 PF13241.6 KXS98301.1 - 0.072 13.5 0.0 0.12 12.8 0.0 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding Trp_halogenase PF04820.14 KXS98301.1 - 0.076 11.8 0.2 0.23 10.3 0.1 1.7 2 0 0 2 2 2 0 Tryptophan halogenase GMC_oxred_N PF00732.19 KXS98302.1 - 4.3e-25 88.7 0.0 2e-21 76.7 0.0 2.8 2 1 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 KXS98302.1 - 1.7e-20 74.0 0.0 3.3e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KXS98302.1 - 9.4e-06 25.0 0.0 1.4e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXS98302.1 - 0.00011 22.3 0.1 0.00033 20.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXS98302.1 - 0.00053 19.3 0.0 0.0011 18.2 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXS98302.1 - 0.004 16.3 0.0 0.0056 15.8 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KXS98302.1 - 0.024 13.9 0.0 0.47 9.7 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXS98302.1 - 0.061 12.6 0.1 0.13 11.4 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.7 KXS98302.1 - 0.12 11.8 0.3 0.48 9.7 0.2 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase BTB PF00651.31 KXS98303.1 - 2.4e-09 37.4 0.1 4.3e-09 36.6 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain AJAP1_PANP_C PF15298.6 KXS98304.1 - 0.0049 17.1 0.7 0.0076 16.5 0.7 1.2 1 0 0 1 1 1 1 AJAP1/PANP C-terminus E_Pc_C PF06752.12 KXS98304.1 - 0.15 12.2 5.2 0.21 11.7 5.2 1.1 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus Response_reg PF00072.24 KXS98305.1 - 1.1e-23 83.5 0.1 2.4e-23 82.4 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 KXS98305.1 - 1.6e-19 70.4 0.0 3.1e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KXS98305.1 - 1.7e-09 37.5 0.2 9.8e-09 35.1 0.1 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 KXS98305.1 - 1.7e-08 34.6 0.3 9.4e-08 32.2 0.3 2.3 1 1 0 1 1 1 1 PAS fold PAS_4 PF08448.10 KXS98305.1 - 2.2e-08 34.3 0.0 0.00012 22.3 0.0 3.2 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 KXS98305.1 - 2.8e-07 30.5 0.0 8.6e-07 28.9 0.0 2.0 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 KXS98305.1 - 1.1e-05 25.6 0.0 0.0042 17.3 0.0 3.0 2 0 0 2 2 2 1 PAS domain PAS_8 PF13188.7 KXS98305.1 - 0.0018 18.2 0.0 0.0066 16.4 0.0 2.0 1 0 0 1 1 1 1 PAS domain Mito_fiss_Elm1 PF06258.11 KXS98305.1 - 0.0061 15.7 0.1 0.013 14.7 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial fission ELM1 DUF4141 PF13605.6 KXS98305.1 - 0.01 15.1 0.0 0.036 13.3 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4141) Rootletin PF15035.6 KXS98305.1 - 0.028 14.5 0.2 0.07 13.2 0.2 1.6 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion PAS_7 PF12860.7 KXS98305.1 - 0.14 12.3 0.0 0.7 10.1 0.0 2.2 1 0 0 1 1 1 0 PAS fold Snf7 PF03357.21 KXS98306.1 - 5.9e-16 58.5 18.2 5.9e-16 58.5 18.2 1.8 1 1 1 2 2 2 1 Snf7 MutS_III PF05192.18 KXS98306.1 - 0.27 11.4 11.4 0.88 9.8 0.1 2.4 2 0 0 2 2 2 0 MutS domain III Glyco_hydro_35 PF01301.19 KXS98308.1 - 1.1e-87 294.6 0.0 2.2e-87 293.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 KXS98308.1 - 9e-58 195.1 2.6 1.7e-57 194.1 2.6 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 KXS98308.1 - 2.1e-56 189.4 13.8 2.8e-33 114.9 0.5 3.2 4 0 0 4 4 4 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 KXS98308.1 - 2.9e-18 65.2 0.0 8.4e-18 63.7 0.0 1.8 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 TPR_11 PF13414.6 KXS98308.1 - 0.11 12.2 1.4 4.1 7.2 0.0 2.6 2 0 0 2 2 2 0 TPR repeat CoA_binding_3 PF13727.6 KXS98310.1 - 0.035 14.1 0.2 0.037 14.1 0.2 1.1 1 0 0 1 1 1 0 CoA-binding domain PEP-CTERM PF07589.11 KXS98310.1 - 4.2 7.6 6.7 8.9 6.6 0.3 2.8 2 1 0 2 2 2 0 PEP-CTERM motif DUF5075 PF16825.5 KXS98311.1 - 0.12 12.0 0.3 0.18 11.5 0.3 1.3 1 0 0 1 1 1 0 IGP family C-type lectin domain IU_nuc_hydro PF01156.19 KXS98312.1 - 0.035 13.7 0.0 0.045 13.3 0.0 1.1 1 0 0 1 1 1 0 Inosine-uridine preferring nucleoside hydrolase Svf1_C PF17187.4 KXS98314.1 - 4.8e-58 195.6 0.0 1.1e-57 194.5 0.0 1.6 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 KXS98314.1 - 2.9e-57 193.3 0.1 3.9e-57 192.9 0.1 1.2 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain CBFD_NFYB_HMF PF00808.23 KXS98315.1 - 3.7e-05 23.9 0.1 6.2e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXS98315.1 - 0.00048 20.5 0.1 0.00067 20.0 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KXS98315.1 - 0.011 15.8 0.0 0.016 15.3 0.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 KXS98315.1 - 0.034 14.2 0.0 0.051 13.6 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated DUF3176 PF11374.8 KXS98316.1 - 2.9e-36 123.9 6.8 1.7e-35 121.5 1.1 3.4 4 0 0 4 4 4 2 Protein of unknown function (DUF3176) BTB PF00651.31 KXS98317.1 - 1.9e-11 44.2 0.1 3.2e-11 43.4 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KXS98318.1 - 1.9e-11 44.2 0.1 3.2e-11 43.4 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain Na_Ca_ex PF01699.24 KXS98319.1 - 5.2e-43 146.6 41.1 1.7e-22 80.0 17.6 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein SpoIIIAH PF12685.7 KXS98319.1 - 0.066 13.0 3.2 0.68 9.7 0.0 2.5 2 0 0 2 2 2 0 SpoIIIAH-like protein Peroxidase_2 PF01328.17 KXS98320.1 - 4.7e-48 164.2 0.0 6e-48 163.9 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 YabA PF06156.13 KXS98321.1 - 5.9e-05 23.6 56.8 0.041 14.5 2.0 7.4 1 1 6 7 7 7 3 Initiation control protein YabA APG6_N PF17675.1 KXS98321.1 - 6.6e-05 23.5 85.1 0.25 11.9 6.6 6.4 1 1 7 8 8 8 5 Apg6 coiled-coil region ERM PF00769.19 KXS98321.1 - 0.00011 22.1 30.9 0.00011 22.1 30.9 3.5 1 1 2 3 3 3 1 Ezrin/radixin/moesin family CENP-F_leu_zip PF10473.9 KXS98321.1 - 0.00031 20.8 79.1 0.018 15.1 13.6 4.8 2 1 1 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fez1 PF06818.15 KXS98321.1 - 0.00036 21.0 79.2 0.033 14.7 25.0 5.3 1 1 5 6 6 6 3 Fez1 GAS PF13851.6 KXS98321.1 - 0.00059 19.2 66.6 0.029 13.7 9.9 5.3 1 1 3 5 5 5 4 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 KXS98321.1 - 0.00098 18.1 72.7 0.053 12.4 15.1 5.0 1 1 4 5 5 5 3 Spc7 kinetochore protein SHE3 PF17078.5 KXS98321.1 - 0.0027 17.5 12.0 0.0027 17.5 12.0 4.6 2 1 2 4 4 4 1 SWI5-dependent HO expression protein 3 ATG16 PF08614.11 KXS98321.1 - 0.0033 17.7 75.5 0.24 11.6 15.1 5.1 1 1 3 4 4 4 3 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.12 KXS98321.1 - 0.0052 16.8 76.2 0.11 12.6 4.4 6.4 1 1 6 8 8 8 4 TPR/MLP1/MLP2-like protein HAP1_N PF04849.13 KXS98321.1 - 0.0075 15.5 11.7 0.0075 15.5 11.7 4.9 1 1 2 4 4 4 1 HAP1 N-terminal conserved region DUF4407 PF14362.6 KXS98321.1 - 0.016 14.6 46.9 0.21 10.9 11.4 4.6 1 1 3 4 4 4 0 Domain of unknown function (DUF4407) Filament PF00038.21 KXS98321.1 - 0.034 13.7 75.0 0.051 13.1 31.1 5.9 1 1 1 4 4 4 0 Intermediate filament protein DUF948 PF06103.11 KXS98321.1 - 0.037 14.3 14.1 7.5 6.9 0.0 5.1 3 3 1 4 4 4 0 Bacterial protein of unknown function (DUF948) BST2 PF16716.5 KXS98321.1 - 0.041 14.5 1.6 0.041 14.5 1.6 7.6 4 2 4 8 8 8 0 Bone marrow stromal antigen 2 Laminin_I PF06008.14 KXS98321.1 - 0.086 12.5 51.7 0.1 12.3 4.2 4.4 3 1 1 4 4 4 0 Laminin Domain I KASH_CCD PF14662.6 KXS98321.1 - 0.09 12.6 70.4 0.13 12.0 7.0 5.0 1 1 4 5 5 5 0 Coiled-coil region of CCDC155 or KASH DUF812 PF05667.11 KXS98321.1 - 0.25 10.2 70.4 1.2 8.0 10.8 3.5 1 1 1 3 3 3 0 Protein of unknown function (DUF812) Golgin_A5 PF09787.9 KXS98321.1 - 0.71 9.3 80.5 0.33 10.4 13.9 4.8 1 1 3 4 4 4 0 Golgin subfamily A member 5 FPP PF05911.11 KXS98321.1 - 0.75 7.9 61.7 0.73 7.9 10.9 2.9 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil GIT_CC PF16559.5 KXS98321.1 - 0.91 9.4 11.1 8.9 6.3 0.4 5.0 5 1 0 5 5 5 0 GIT coiled-coil Rho guanine nucleotide exchange factor CT_C_D PF02682.16 KXS98321.1 - 1.2 8.8 3.9 1.1 9.0 0.3 2.6 2 1 0 2 2 2 0 Carboxyltransferase domain, subdomain C and D Baculo_PEP_C PF04513.12 KXS98321.1 - 1.3 9.1 9.4 3.3 7.7 0.5 4.2 3 2 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMF_TATA_bd PF12325.8 KXS98321.1 - 1.4 9.1 70.1 0.03 14.5 10.6 6.9 1 1 5 8 8 8 0 TATA element modulatory factor 1 TATA binding CALCOCO1 PF07888.11 KXS98321.1 - 1.8 7.3 85.1 0.14 11.0 26.8 3.8 1 1 3 4 4 4 0 Calcium binding and coiled-coil domain (CALCOCO1) like HMMR_N PF15905.5 KXS98321.1 - 2 7.8 67.5 0.02 14.4 15.7 4.8 1 1 4 5 5 5 0 Hyaluronan mediated motility receptor N-terminal MCPsignal PF00015.21 KXS98321.1 - 2.6 7.8 14.5 0.45 10.3 1.7 3.9 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain TMPIT PF07851.13 KXS98321.1 - 3.7 6.7 46.9 0.38 10.0 2.6 5.3 2 2 2 5 5 5 0 TMPIT-like protein DUF3450 PF11932.8 KXS98321.1 - 4.7 6.4 51.1 0.25 10.6 4.0 6.2 1 1 4 7 7 7 0 Protein of unknown function (DUF3450) EzrA PF06160.12 KXS98321.1 - 6.1 4.9 57.3 0.051 11.8 5.7 4.2 1 1 3 4 4 4 0 Septation ring formation regulator, EzrA Fungal_trans_2 PF11951.8 KXS98322.1 - 3e-42 144.8 2.5 5.6e-42 143.9 2.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS98322.1 - 1.1e-06 28.7 9.0 1.9e-06 27.9 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pinin_SDK_N PF04697.13 KXS98322.1 - 0.12 13.0 2.6 0.24 12.0 2.6 1.5 1 0 0 1 1 1 0 pinin/SDK conserved region Endomucin PF07010.12 KXS98322.1 - 0.91 9.4 7.9 1.5 8.8 7.9 1.2 1 0 0 1 1 1 0 Endomucin CPSase_L_D2 PF02786.17 KXS98324.1 - 2.8e-114 379.9 0.1 1.3e-82 276.4 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain GATase PF00117.28 KXS98324.1 - 5.7e-49 166.5 0.0 1.2e-48 165.4 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I OTCace_N PF02729.21 KXS98324.1 - 1.9e-46 157.8 0.1 4.8e-46 156.4 0.1 1.8 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_sm_chain PF00988.22 KXS98324.1 - 4.7e-46 155.8 0.0 4.5e-45 152.6 0.0 2.3 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain CPSase_L_D3 PF02787.19 KXS98324.1 - 1.2e-39 135.4 0.0 2.6e-39 134.3 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 KXS98324.1 - 7.3e-30 104.1 0.0 1.6e-29 103.0 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Dala_Dala_lig_C PF07478.13 KXS98324.1 - 1.4e-19 70.4 0.3 8.4e-10 38.5 0.1 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KXS98324.1 - 9.3e-18 64.4 0.1 2.9e-09 36.7 0.0 2.6 3 0 0 3 3 3 2 ATP-grasp domain MGS PF02142.22 KXS98324.1 - 9.3e-18 64.2 0.0 3.6e-17 62.3 0.0 2.2 1 0 0 1 1 1 1 MGS-like domain ATPgrasp_Ter PF15632.6 KXS98324.1 - 4e-10 39.5 0.0 0.00015 21.6 0.0 2.7 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 KXS98324.1 - 1.3e-06 28.5 0.6 0.015 15.3 0.1 2.9 3 0 0 3 3 3 2 ATP-grasp domain DJ-1_PfpI PF01965.24 KXS98324.1 - 1.8e-06 27.9 0.1 0.0054 16.6 0.0 4.2 5 0 0 5 5 4 1 DJ-1/PfpI family GARS_A PF01071.19 KXS98324.1 - 9.8e-06 25.5 0.2 0.18 11.6 0.0 2.9 2 1 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Peptidase_C26 PF07722.13 KXS98324.1 - 3.1e-05 23.9 0.2 0.0021 17.8 0.2 2.5 1 1 0 1 1 1 1 Peptidase C26 RimK PF08443.11 KXS98324.1 - 0.0011 18.6 0.0 0.14 11.8 0.0 2.7 2 0 0 2 2 2 1 RimK-like ATP-grasp domain TrkA_N PF02254.18 KXS98324.1 - 0.029 14.6 0.0 0.18 12.1 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain Peroxidase_2 PF01328.17 KXS98325.1 - 1.5e-43 149.5 0.0 2.3e-43 148.9 0.0 1.3 1 0 0 1 1 1 1 Peroxidase, family 2 Beta-lactamase PF00144.24 KXS98326.1 - 2.3e-31 109.2 0.0 3.3e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF4185 PF13810.6 KXS98328.1 - 1.9e-10 40.5 0.3 2.6e-10 40.1 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4185) MFS_1 PF07690.16 KXS98329.1 - 4.3e-08 32.5 11.3 8.6e-08 31.5 11.3 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily YitT_membrane PF02588.15 KXS98329.1 - 0.025 14.0 0.0 0.025 14.0 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised 5xTM membrane BCR, YitT family COG1284 MFS_2 PF13347.6 KXS98329.1 - 0.03 12.9 4.8 0.048 12.2 4.8 1.3 1 1 0 1 1 1 0 MFS/sugar transport protein Apolipoprotein PF01442.18 KXS98330.1 - 0.0071 16.2 6.3 0.011 15.6 6.3 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain CREPT PF16566.5 KXS98330.1 - 0.0093 16.1 5.7 0.016 15.4 5.7 1.3 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour Atg14 PF10186.9 KXS98330.1 - 0.046 12.8 0.7 0.066 12.3 0.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ABC_tran_CTD PF16326.5 KXS98330.1 - 0.051 13.8 8.6 0.8 10.0 0.9 2.5 1 1 1 2 2 2 0 ABC transporter C-terminal domain Phage_Mu_Gam PF07352.12 KXS98330.1 - 0.061 13.2 5.8 0.37 10.7 4.1 2.4 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein DUF1151 PF06625.11 KXS98330.1 - 0.084 12.8 5.3 0.14 12.1 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) DUF773 PF05600.12 KXS98330.1 - 0.097 11.4 7.8 0.051 12.3 3.2 2.0 2 0 0 2 2 2 0 CDK5 regulatory subunit-associated protein 3 PilJ PF13675.6 KXS98330.1 - 0.1 12.7 1.1 0.2 11.7 1.1 1.5 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Ax_dynein_light PF10211.9 KXS98330.1 - 0.13 12.2 5.4 0.21 11.5 5.4 1.3 1 0 0 1 1 1 0 Axonemal dynein light chain YabA PF06156.13 KXS98330.1 - 0.15 12.7 4.4 0.12 13.0 1.2 2.2 1 1 1 2 2 2 0 Initiation control protein YabA PCRF PF03462.18 KXS98330.1 - 0.16 11.9 5.6 0.31 10.9 5.6 1.4 1 0 0 1 1 1 0 PCRF domain PI3K_1B_p101 PF10486.9 KXS98330.1 - 0.18 9.5 2.3 0.25 9.1 2.3 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Lipoprotein_6 PF01441.19 KXS98330.1 - 0.28 11.2 7.4 0.064 13.3 4.0 1.6 2 0 0 2 2 2 0 Lipoprotein YebO PF13974.6 KXS98330.1 - 0.29 11.2 2.0 0.71 10.0 2.0 1.7 1 0 0 1 1 1 0 YebO-like protein Prefoldin_2 PF01920.20 KXS98330.1 - 0.41 10.6 7.9 0.77 9.7 7.9 1.5 1 0 0 1 1 1 0 Prefoldin subunit AAA_23 PF13476.6 KXS98330.1 - 0.54 10.7 5.3 0.77 10.2 4.9 1.4 1 1 0 1 1 1 0 AAA domain APG6_N PF17675.1 KXS98330.1 - 1.6 9.3 10.7 2.8 8.5 10.7 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region Lebercilin PF15619.6 KXS98331.1 - 0.046 13.4 11.3 0.062 13.0 11.0 1.5 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Helicase_IV_N PF12462.8 KXS98331.1 - 0.13 12.1 2.1 0.22 11.5 2.1 1.3 1 0 0 1 1 1 0 DNA helicase IV / RNA helicase N terminal DUF2570 PF10828.8 KXS98331.1 - 1.6 8.6 7.7 1.2 9.0 5.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) DUF3935 PF13071.6 KXS98335.1 - 0.081 13.5 0.1 0.35 11.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3935) Nmad4 PF18756.1 KXS98335.1 - 0.092 13.1 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Nucleotide modification associated domain 4 Vsr PF03852.15 KXS98336.1 - 0.026 14.4 0.0 0.096 12.5 0.0 1.9 2 0 0 2 2 2 0 DNA mismatch endonuclease Vsr PP28 PF10252.9 KXS98337.1 - 4.8e-29 100.6 19.7 4.8e-29 100.6 19.7 3.3 2 1 1 3 3 3 2 Casein kinase substrate phosphoprotein PP28 Spore_YhaL PF14147.6 KXS98337.1 - 0.64 9.8 3.5 2.6 7.8 3.5 2.1 1 0 0 1 1 1 0 Sporulation protein YhaL p450 PF00067.22 KXS98338.1 - 1.1e-54 185.9 0.0 1.3e-54 185.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Aldo_ket_red PF00248.21 KXS98340.1 - 9.6e-46 156.3 0.0 5.6e-44 150.5 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family TcpQ PF10671.9 KXS98340.1 - 0.094 12.9 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Toxin co-regulated pilus biosynthesis protein Q Hamartin PF04388.12 KXS98341.1 - 2.7 6.6 8.5 3.9 6.0 1.3 2.1 2 0 0 2 2 2 0 Hamartin protein ATG22 PF11700.8 KXS98342.1 - 6.1e-191 635.2 9.0 7.5e-191 634.9 9.0 1.1 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 KXS98342.1 - 0.00015 20.8 47.7 0.00073 18.6 4.0 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.6 KXS98342.1 - 0.029 12.9 29.4 0.046 12.3 13.1 2.6 2 1 0 2 2 2 0 MFS/sugar transport protein GRDA PF04723.14 KXS98343.1 - 2.3 8.0 4.8 1.6 8.5 1.7 1.8 1 1 1 2 2 2 0 Glycine reductase complex selenoprotein A DUF3196 PF11428.8 KXS98344.1 - 0.11 12.0 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3196) HET PF06985.11 KXS98345.1 - 4.2e-25 88.8 0.3 8.3e-25 87.8 0.3 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DASH_Spc34 PF08657.10 KXS98346.1 - 0.16 11.7 0.0 0.21 11.3 0.0 1.1 1 0 0 1 1 1 0 DASH complex subunit Spc34 HATPase_c PF02518.26 KXS98347.1 - 5e-28 97.8 0.0 2.6e-27 95.5 0.0 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXS98347.1 - 2.3e-26 92.1 0.0 4.9e-26 91.1 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KXS98347.1 - 5.3e-15 55.2 0.0 1.6e-14 53.7 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 KXS98347.1 - 0.0011 19.2 0.2 0.058 13.8 0.0 3.2 3 0 0 3 3 3 1 HAMP domain Prefoldin PF02996.17 KXS98348.1 - 4.9e-29 100.7 0.0 8.9e-29 99.8 0.0 1.4 2 0 0 2 2 2 1 Prefoldin subunit GAS PF13851.6 KXS98348.1 - 0.0066 15.8 0.4 0.38 10.1 0.1 2.2 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding CCDC106 PF15794.5 KXS98348.1 - 0.026 14.2 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Prefoldin_2 PF01920.20 KXS98348.1 - 0.039 13.9 0.4 0.59 10.1 0.1 2.2 2 0 0 2 2 2 0 Prefoldin subunit Cep3 PF16846.5 KXS98348.1 - 0.04 12.4 0.0 0.055 11.9 0.0 1.1 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit B Lebercilin PF15619.6 KXS98348.1 - 0.076 12.7 0.7 0.73 9.5 0.1 2.0 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Syntaxin-6_N PF09177.11 KXS98348.1 - 0.088 13.4 0.9 5.1 7.7 0.9 2.4 1 1 0 1 1 1 0 Syntaxin 6, N-terminal THOC7 PF05615.13 KXS98348.1 - 0.15 12.3 2.0 0.69 10.2 1.6 2.0 1 1 1 2 2 2 0 Tho complex subunit 7 SAT PF16073.5 KXS98349.1 - 1.3e-82 277.1 0.7 4.2e-82 275.5 0.1 2.1 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis ketoacyl-synt PF00109.26 KXS98349.1 - 1.3e-77 260.9 0.0 4e-77 259.2 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KXS98349.1 - 1.5e-43 149.5 0.0 3.4e-43 148.4 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXS98349.1 - 1e-33 115.9 3.6 3.9e-33 114.0 2.9 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Prefoldin PF02996.17 KXS98349.1 - 2e-27 95.5 0.0 4.9e-27 94.2 0.0 1.7 1 0 0 1 1 1 1 Prefoldin subunit PP-binding PF00550.25 KXS98349.1 - 7.7e-26 90.2 6.3 1.5e-13 50.9 0.4 3.3 3 0 0 3 3 3 2 Phosphopantetheine attachment site Thioesterase PF00975.20 KXS98349.1 - 4.6e-18 66.2 0.6 1.9e-16 60.9 0.0 3.2 2 1 0 2 2 2 1 Thioesterase domain PS-DH PF14765.6 KXS98349.1 - 2.2e-14 53.4 0.0 4.6e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_6 PF12697.7 KXS98349.1 - 2.3e-05 25.1 2.9 0.0018 18.9 1.0 3.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family KAsynt_C_assoc PF16197.5 KXS98349.1 - 0.00024 21.5 0.0 0.00062 20.2 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 KXS98349.1 - 0.00033 20.1 0.1 0.0016 17.9 0.0 2.2 2 0 0 2 2 2 1 Thiolase, N-terminal domain Abhydrolase_3 PF07859.13 KXS98349.1 - 0.062 13.2 0.0 0.2 11.5 0.0 1.9 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2974 PF11187.8 KXS98349.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) SMC_N PF02463.19 KXS98350.1 - 2.9e-66 223.1 40.9 3.8e-65 219.4 40.9 2.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KXS98350.1 - 6.3e-24 84.5 0.0 2.1e-23 82.8 0.0 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KXS98350.1 - 2.7e-12 47.1 0.7 3.7e-05 23.7 0.0 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KXS98350.1 - 3.4e-09 36.9 12.3 3.4e-09 36.9 12.3 4.3 2 2 1 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 KXS98350.1 - 0.00022 20.9 0.0 0.00046 19.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain HOOK PF05622.12 KXS98350.1 - 0.0013 17.0 19.0 0.0013 17.0 19.0 6.1 2 2 3 6 6 6 1 HOOK protein Myosin_tail_1 PF01576.19 KXS98350.1 - 0.14 9.9 134.3 0.089 10.6 43.0 3.7 2 2 1 3 3 3 0 Myosin tail Fez1 PF06818.15 KXS98350.1 - 0.15 12.5 121.5 0.11 13.0 14.0 6.3 2 2 2 5 5 5 0 Fez1 ABC_tran PF00005.27 KXS98350.1 - 1.5 9.3 0.0 1.5 9.3 0.0 6.6 3 2 1 4 4 4 0 ABC transporter ApoO PF09769.9 KXS98351.1 - 3.2e-42 143.6 0.1 1e-41 141.9 0.0 1.8 2 0 0 2 2 2 1 Apolipoprotein O adh_short_C2 PF13561.6 KXS98353.1 - 2.2e-57 194.3 1.8 3.3e-57 193.8 1.8 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS98353.1 - 1.3e-49 168.3 3.5 1.8e-49 167.9 3.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS98353.1 - 9.1e-13 48.5 1.3 1.3e-12 48.0 1.3 1.1 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 KXS98353.1 - 0.022 14.1 0.2 0.061 12.6 0.0 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 KXS98353.1 - 0.069 12.6 0.6 0.11 11.9 0.6 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KXS98353.1 - 0.73 9.7 3.3 0.99 9.3 2.0 1.9 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CLP_protease PF00574.23 KXS98354.1 - 7e-75 250.9 0.0 8.6e-75 250.6 0.0 1.0 1 0 0 1 1 1 1 Clp protease SDH_sah PF01972.16 KXS98354.1 - 0.1 11.6 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Serine dehydrogenase proteinase CLP_protease PF00574.23 KXS98355.1 - 7e-75 250.9 0.0 8.6e-75 250.6 0.0 1.0 1 0 0 1 1 1 1 Clp protease SDH_sah PF01972.16 KXS98355.1 - 0.1 11.6 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Serine dehydrogenase proteinase AMP-binding PF00501.28 KXS98356.1 - 1.6e-141 471.8 0.0 2.2e-71 240.7 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 KXS98356.1 - 5e-98 328.7 0.0 5.8e-69 232.9 0.0 2.9 3 0 0 3 3 3 2 Condensation domain PP-binding PF00550.25 KXS98356.1 - 1.3e-22 79.9 0.2 2e-11 44.1 0.1 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KXS98356.1 - 6e-07 30.4 0.0 0.079 13.9 0.0 3.8 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain Methyltransf_23 PF13489.6 KXS98356.1 - 5.7e-05 23.0 0.0 0.00014 21.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS98356.1 - 0.00025 21.7 0.0 0.00082 20.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS98356.1 - 0.0041 17.8 0.0 0.013 16.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS98356.1 - 0.011 15.6 0.0 0.036 13.9 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 KXS98356.1 - 0.019 15.6 0.0 0.058 14.0 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_C48 PF02902.19 KXS98357.1 - 2.9e-14 53.4 1.2 4.2e-14 52.9 1.2 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DnaJ PF00226.31 KXS98358.1 - 1.2e-10 41.3 1.9 2.5e-10 40.3 1.9 1.6 1 0 0 1 1 1 1 DnaJ domain DUF4820 PF16091.5 KXS98359.1 - 0.1 11.9 0.1 0.21 10.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) SDA1 PF05285.12 KXS98359.1 - 0.99 8.8 8.5 1.4 8.3 8.5 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KXS98359.1 - 2.4 6.3 13.6 3.2 5.9 13.6 1.1 1 0 0 1 1 1 0 Nop14-like family Ost4 PF10215.9 KXS98360.1 - 0.15 11.9 0.9 0.54 10.1 0.9 2.0 1 0 0 1 1 1 0 Oligosaccaryltransferase Peptidase_C48 PF02902.19 KXS98361.1 - 6.8e-05 22.8 0.3 0.00016 21.6 0.3 1.6 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain adh_short PF00106.25 KXS98362.1 - 1.5e-23 83.3 0.0 7.3e-21 74.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXS98362.1 - 1e-15 57.9 0.0 8.6e-14 51.7 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS98362.1 - 1.3e-05 25.2 0.0 2e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KXS98362.1 - 0.12 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF3328 PF11807.8 KXS98363.1 - 4.8e-31 108.2 0.5 6.1e-31 107.9 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) FAS_I_H PF18314.1 KXS98363.1 - 0.16 11.6 0.2 0.3 10.7 0.2 1.3 1 0 0 1 1 1 0 Fatty acid synthase type I helical domain Cupin_2 PF07883.11 KXS98366.1 - 0.0023 17.6 0.1 0.0023 17.6 0.1 2.1 3 0 0 3 3 3 1 Cupin domain YcaO PF02624.16 KXS98366.1 - 0.058 12.7 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 YcaO cyclodehydratase, ATP-ad Mg2+-binding ApbA_C PF08546.11 KXS98367.1 - 1e-28 100.0 0.1 1.6e-28 99.4 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KXS98367.1 - 5e-22 78.2 0.0 1.2e-21 77.0 0.0 1.7 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DUF3552 PF12072.8 KXS98368.1 - 0.00076 19.0 25.0 0.0011 18.5 25.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) Exonuc_VII_L PF02601.15 KXS98368.1 - 0.039 13.5 0.1 0.044 13.4 0.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.9 KXS98368.1 - 0.42 9.6 6.6 0.61 9.1 6.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 OmpH PF03938.14 KXS98368.1 - 0.62 10.4 10.9 0.98 9.8 10.9 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) ECM11 PF15463.6 KXS98368.1 - 0.83 10.2 14.3 1.1 9.8 12.9 1.9 1 1 1 2 2 2 0 Extracellular mutant protein 11 MPS2 PF17060.5 KXS98368.1 - 5.3 6.2 9.3 8.1 5.6 9.3 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 Zn_clus PF00172.18 KXS98371.1 - 3.9e-08 33.3 12.5 9.1e-08 32.1 12.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXS98371.1 - 1.9e-05 23.8 0.8 1.9e-05 23.8 0.8 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KXS98371.1 - 3.1e-05 24.2 13.5 0.00012 22.3 1.8 3.8 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXS98371.1 - 0.00026 21.3 3.9 0.00026 21.3 3.9 4.6 4 1 1 5 5 5 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXS98371.1 - 0.0058 17.4 1.0 0.0058 17.4 1.0 4.4 4 1 0 4 4 4 2 C2H2-type zinc finger Cytochrom_CIII PF02085.16 KXS98371.1 - 1.1 9.6 6.6 3.4 8.1 6.6 1.8 1 0 0 1 1 1 0 Class III cytochrome C family zf-C2H2_jaz PF12171.8 KXS98371.1 - 1.1 9.6 3.9 15 6.0 0.3 3.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Abhydrolase_2 PF02230.16 KXS98372.1 - 7e-35 120.8 0.0 9.7e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase BAAT_C PF08840.11 KXS98372.1 - 0.0019 18.1 0.0 0.0074 16.2 0.0 1.9 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 KXS98372.1 - 0.0078 15.5 0.1 2.1 7.5 0.0 2.6 3 0 0 3 3 3 2 Serine aminopeptidase, S33 FSH1 PF03959.13 KXS98372.1 - 0.021 14.5 0.0 0.094 12.4 0.0 2.1 2 1 0 2 2 2 0 Serine hydrolase (FSH1) Lipase_GDSL_2 PF13472.6 KXS98373.1 - 4e-09 37.1 2.3 1.3e-08 35.5 2.3 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXS98373.1 - 5.1e-07 29.9 0.0 1e-06 28.9 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase KASH_CCD PF14662.6 KXS98375.1 - 0.001 18.9 2.7 0.001 18.9 2.7 2.2 1 1 1 2 2 2 1 Coiled-coil region of CCDC155 or KASH bZIP_1 PF00170.21 KXS98375.1 - 0.0011 19.0 1.6 0.007 16.4 0.8 2.3 1 1 1 2 2 2 2 bZIP transcription factor TSC22 PF01166.18 KXS98375.1 - 0.022 15.1 2.1 0.12 12.7 0.5 2.6 1 1 1 2 2 2 0 TSC-22/dip/bun family bZIP_2 PF07716.15 KXS98375.1 - 0.025 14.6 5.5 0.22 11.6 0.8 2.7 1 1 1 2 2 2 0 Basic region leucine zipper HALZ PF02183.18 KXS98375.1 - 0.057 13.7 0.7 2.1 8.6 0.2 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper Shugoshin_N PF07558.11 KXS98375.1 - 0.098 12.5 0.3 0.21 11.5 0.3 1.5 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region TMF_DNA_bd PF12329.8 KXS98375.1 - 0.37 10.8 9.0 1.3 9.1 8.9 2.0 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding ADIP PF11559.8 KXS98375.1 - 0.7 10.0 16.1 1.5 8.9 13.8 2.6 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding YabA PF06156.13 KXS98375.1 - 5 7.8 8.3 3 8.5 4.6 2.5 1 1 1 2 2 2 0 Initiation control protein YabA KASH_CCD PF14662.6 KXS98376.1 - 0.012 15.5 5.6 0.012 15.5 5.6 3.1 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH SAS4 PF15460.6 KXS98376.1 - 0.014 15.4 8.3 0.014 15.4 8.3 2.0 2 0 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 DUF2112 PF09885.9 KXS98376.1 - 0.097 12.7 0.4 0.3 11.1 0.4 1.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2112) PKHD_C PF18331.1 KXS98376.1 - 0.26 11.4 2.0 2.5 8.2 0.0 2.9 2 1 0 2 2 2 0 PKHD-type hydroxylase C-terminal domain DUF572 PF04502.13 KXS98376.1 - 9.9 5.7 23.5 16 5.0 23.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) PRA-PH PF01503.17 KXS98377.1 - 0.051 14.0 0.0 0.079 13.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase F-box PF00646.33 KXS98378.1 - 0.0031 17.4 0.0 0.011 15.7 0.0 1.9 1 1 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXS98378.1 - 0.028 14.3 0.1 0.16 11.9 0.1 2.0 1 1 0 1 1 1 0 F-box-like F-box-like_2 PF13013.6 KXS98378.1 - 0.069 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 F-box-like domain QRPTase_C PF01729.19 KXS98385.1 - 2.2e-52 177.2 0.0 2.8e-52 176.9 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 KXS98385.1 - 9.5e-22 76.9 0.0 2.3e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain ADH_zinc_N PF00107.26 KXS98385.1 - 0.004 17.1 0.3 0.023 14.7 0.2 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase CFEM PF05730.11 KXS98386.1 - 1.3e-11 44.4 11.6 2.2e-11 43.7 11.6 1.3 1 0 0 1 1 1 1 CFEM domain DUF373 PF04123.13 KXS98386.1 - 0.13 11.7 2.0 0.21 11.0 1.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF373) Gamma-thionin PF00304.20 KXS98386.1 - 0.66 10.3 3.3 0.93 9.8 1.7 2.1 2 0 0 2 2 2 0 Gamma-thionin family Peptidase_M3 PF01432.20 KXS98387.1 - 2.6e-124 416.0 0.0 4.2e-124 415.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 KXS98387.1 - 0.0063 16.2 0.2 0.012 15.3 0.2 1.3 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M91 PF14891.6 KXS98387.1 - 0.049 14.0 0.0 0.14 12.5 0.0 1.7 2 0 0 2 2 2 0 Effector protein Peptidase_M2 PF01401.18 KXS98387.1 - 0.13 10.8 0.8 0.33 9.5 0.1 1.9 2 1 0 2 2 2 0 Angiotensin-converting enzyme cpYpsA PF12694.7 KXS98388.1 - 0.023 14.5 0.0 0.047 13.5 0.0 1.4 1 0 0 1 1 1 0 Circularly permutated YpsA SLOG family NUDE_C PF04880.13 KXS98389.1 - 10 6.6 11.3 19 5.7 4.7 2.6 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region Peroxidase_2 PF01328.17 KXS98390.1 - 3.7e-39 135.2 0.0 4.9e-39 134.8 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 Med14 PF08638.11 KXS98391.1 - 6.5e-56 188.8 0.0 1.8e-55 187.4 0.0 1.7 1 0 0 1 1 1 1 Mediator complex subunit MED14 tRNA-synt_2b PF00587.25 KXS98392.1 - 7.5e-33 114.0 0.1 1.6e-30 106.4 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KXS98392.1 - 4.1e-15 55.7 0.1 9e-15 54.6 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 KXS98392.1 - 1.2e-13 51.0 0.0 2.4e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 KXS98392.1 - 4.1e-12 46.0 0.0 1e-11 44.7 0.0 1.7 1 0 0 1 1 1 1 TGS domain UCH PF00443.29 KXS98393.1 - 1.7e-52 178.5 0.1 3e-52 177.7 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXS98393.1 - 5.4e-21 75.5 2.5 3.7e-16 59.6 0.3 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KXS98393.1 - 0.0031 17.8 1.6 0.0031 17.8 1.6 2.9 2 2 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein CpeT PF06206.11 KXS98393.1 - 0.095 12.7 0.3 0.18 11.8 0.3 1.3 1 0 0 1 1 1 0 CpeT/CpcT family (DUF1001) zf-C2H2 PF00096.26 KXS98394.1 - 0.0082 16.6 0.2 0.0082 16.6 0.2 3.6 3 1 0 3 3 3 2 Zinc finger, C2H2 type FOXP-CC PF16159.5 KXS98394.1 - 0.096 13.3 0.1 0.096 13.3 0.1 3.1 3 0 0 3 3 3 0 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 KXS98394.1 - 0.2 12.6 0.2 0.2 12.6 0.2 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger PS-DH PF14765.6 KXS98395.1 - 1.3e-51 175.6 0.2 2.3e-51 174.8 0.2 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 KXS98395.1 - 1.3e-39 136.0 7.1 4.6e-38 130.9 7.1 2.7 1 1 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 KXS98395.1 - 2.8e-17 63.2 0.0 5.9e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Methyltransf_12 PF08242.12 KXS98395.1 - 2.2e-11 44.3 0.0 2.8e-10 40.8 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS98395.1 - 1.2e-08 35.5 0.0 4e-07 30.7 0.0 3.6 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS98395.1 - 2.1e-07 30.8 0.0 2.7e-06 27.2 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain PP-binding PF00550.25 KXS98395.1 - 3.3e-07 30.6 0.0 8.5e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.12 KXS98395.1 - 4e-05 24.2 0.0 0.0005 20.7 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 KXS98395.1 - 0.0026 18.8 0.0 0.018 16.1 0.0 2.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_28 PF02636.17 KXS98395.1 - 0.009 15.7 0.0 0.024 14.2 0.0 1.7 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Ubie_methyltran PF01209.18 KXS98395.1 - 0.058 12.7 0.0 0.16 11.3 0.0 1.7 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family THF_DHG_CYH_C PF02882.19 KXS98395.1 - 0.14 11.4 0.0 0.56 9.5 0.0 2.0 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ketoacyl-synt PF00109.26 KXS98397.1 - 3.7e-56 190.5 0.0 8.2e-56 189.4 0.0 1.6 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KXS98397.1 - 1.1e-34 119.0 0.1 3e-34 117.6 0.1 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 KXS98397.1 - 1e-14 54.8 0.3 1.6e-14 54.2 0.3 1.2 1 0 0 1 1 1 1 Acyl transferase domain KAsynt_C_assoc PF16197.5 KXS98397.1 - 2.4e-13 50.5 0.0 4.8e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension AAA_13 PF13166.6 KXS98398.1 - 0.0049 15.6 1.8 0.0056 15.4 1.8 1.1 1 0 0 1 1 1 1 AAA domain CorA PF01544.18 KXS98398.1 - 0.0057 16.0 2.6 0.0071 15.7 2.6 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Exonuc_VII_L PF02601.15 KXS98398.1 - 0.0059 16.2 1.5 0.0071 15.9 1.5 1.0 1 0 0 1 1 1 1 Exonuclease VII, large subunit ORF6C PF10552.9 KXS98398.1 - 0.0076 16.3 6.2 0.053 13.6 1.2 2.2 1 1 1 2 2 2 1 ORF6C domain DUF3510 PF12022.8 KXS98398.1 - 0.0084 16.5 3.0 0.014 15.7 3.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3510) MIF4G_like_2 PF09090.11 KXS98398.1 - 0.024 14.1 4.4 0.033 13.7 4.4 1.1 1 0 0 1 1 1 0 MIF4G like HEPN_RES_NTD1 PF18870.1 KXS98398.1 - 0.047 13.9 0.1 0.062 13.5 0.1 1.2 1 0 0 1 1 1 0 HEPN/RES N-terminal domain 1 P4Ha_N PF08336.11 KXS98398.1 - 0.05 13.6 1.6 0.05 13.6 1.6 2.2 1 1 2 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region LUC7 PF03194.15 KXS98398.1 - 0.071 12.8 4.4 0.091 12.4 4.4 1.1 1 0 0 1 1 1 0 LUC7 N_terminus Planc_extracel PF07595.12 KXS98398.1 - 0.074 12.9 2.2 15 5.6 0.0 3.4 3 0 0 3 3 3 0 Planctomycete extracellular CLZ PF16526.5 KXS98398.1 - 0.12 12.7 7.3 1.1 9.7 0.5 2.3 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TcpS PF17456.2 KXS98398.1 - 0.15 12.1 9.3 4.3 7.4 9.3 2.2 1 1 0 1 1 1 0 Toxin-coregulated pilus protein S SlyX PF04102.12 KXS98398.1 - 0.15 12.7 4.1 1.3 9.6 0.3 2.6 1 1 0 2 2 2 0 SlyX AAA_23 PF13476.6 KXS98398.1 - 0.17 12.3 4.9 0.23 12.0 4.9 1.2 1 0 0 1 1 1 0 AAA domain bZIP_1 PF00170.21 KXS98398.1 - 0.2 11.8 12.8 2 8.6 1.1 3.0 2 1 1 3 3 3 0 bZIP transcription factor DUF1515 PF07439.11 KXS98398.1 - 0.23 11.5 1.9 0.37 10.8 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Prefoldin_2 PF01920.20 KXS98398.1 - 0.24 11.4 10.2 0.2 11.6 3.0 2.2 1 1 1 2 2 2 0 Prefoldin subunit LMSTEN PF07988.12 KXS98398.1 - 0.45 10.0 11.0 0.32 10.5 2.3 2.5 2 0 0 2 2 2 0 LMSTEN motif YnfE PF17452.2 KXS98398.1 - 1.1 9.6 4.3 0.5 10.7 2.0 1.7 2 0 0 2 2 1 0 Uncharacterized YnfE-like Fib_alpha PF08702.10 KXS98398.1 - 1.1 9.4 5.3 2 8.6 5.3 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Rota_NSP3 PF01665.16 KXS98398.1 - 1.2 8.2 6.0 1.9 7.6 6.0 1.4 1 1 0 1 1 1 0 Rotavirus non-structural protein NSP3 BMFP PF04380.13 KXS98398.1 - 1.3 9.5 8.2 11 6.6 0.1 3.1 3 1 1 4 4 3 0 Membrane fusogenic activity bZIP_2 PF07716.15 KXS98398.1 - 1.5 9.0 14.3 7.4 6.7 6.3 2.8 2 1 1 3 3 3 0 Basic region leucine zipper TSC22 PF01166.18 KXS98398.1 - 1.6 9.1 10.2 5 7.5 3.8 2.7 2 1 1 3 3 3 0 TSC-22/dip/bun family LapA_dom PF06305.11 KXS98398.1 - 1.7 8.5 8.6 1.1 9.1 0.4 2.3 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF4094 PF13334.6 KXS98398.1 - 1.9 8.9 5.8 55 4.3 5.8 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) Csm1_N PF18504.1 KXS98398.1 - 2.4 8.5 11.8 1.1 9.6 2.1 2.7 2 2 1 3 3 3 0 Csm1 N-terminal domain DivIC PF04977.15 KXS98398.1 - 7.9 6.3 12.7 1.1 9.1 2.5 2.6 2 1 1 3 3 3 0 Septum formation initiator SLATT_fungal PF18142.1 KXS98400.1 - 1.1e-12 47.9 4.2 6e-12 45.6 4.2 2.1 1 1 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain DUF1664 PF07889.12 KXS98400.1 - 0.025 14.6 0.3 0.04 13.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Cep57_MT_bd PF06657.13 KXS98400.1 - 0.057 13.9 1.6 0.12 12.9 1.6 1.5 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 p450 PF00067.22 KXS98401.1 - 1e-26 93.7 0.0 1.3e-26 93.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Sulfotransfer_4 PF17784.1 KXS98402.1 - 2e-57 194.5 0.0 2.4e-57 194.2 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KXS98402.1 - 0.0002 21.8 0.1 0.014 15.8 0.1 2.2 1 1 0 1 1 1 1 Sulfotransferase family HAD PF12710.7 KXS98403.1 - 0.0017 18.8 0.0 0.018 15.4 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Glyco_transf_4 PF13439.6 KXS98403.1 - 0.048 13.7 0.1 0.22 11.5 0.0 1.9 2 0 0 2 2 2 0 Glycosyltransferase Family 4 K_oxygenase PF13434.6 KXS98404.1 - 1.2e-11 44.4 0.0 2.8e-09 36.6 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KXS98404.1 - 1e-09 38.1 0.0 1.2e-07 31.4 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KXS98404.1 - 1.5e-09 36.8 0.0 2e-05 23.3 0.0 3.1 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KXS98404.1 - 7.1e-09 35.3 0.0 4.1e-06 26.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXS98404.1 - 7.6e-08 32.5 0.0 1.7e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXS98404.1 - 0.00011 21.9 0.0 0.76 9.3 0.0 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.17 KXS98404.1 - 0.0002 20.7 0.0 0.00033 20.0 0.0 1.2 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 KXS98404.1 - 0.00034 19.5 0.0 0.66 8.6 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_9 PF13454.6 KXS98404.1 - 0.00099 19.1 0.1 0.59 10.1 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KXS98404.1 - 0.0063 15.6 0.1 0.029 13.4 0.1 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 KXS98404.1 - 0.1 11.6 0.0 8.9 5.3 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A NmrA PF05368.13 KXS98408.1 - 1.2e-26 93.7 0.0 1.5e-26 93.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXS98408.1 - 1.1e-09 38.4 0.0 1.7e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXS98408.1 - 7.1e-05 22.4 0.0 0.0032 17.0 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KXS98408.1 - 0.00023 21.6 0.0 0.00052 20.4 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KXS98408.1 - 0.00073 18.6 0.0 0.0013 17.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DXP_reductoisom PF02670.16 KXS98408.1 - 0.0029 18.3 0.1 0.0059 17.3 0.0 1.6 2 0 0 2 2 2 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase Sacchrp_dh_NADP PF03435.18 KXS98408.1 - 0.013 15.8 0.1 0.022 15.0 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 KXS98408.1 - 0.02 14.8 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.15 KXS98408.1 - 0.045 12.9 0.0 0.067 12.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Glu_dehyd_C PF16912.5 KXS98408.1 - 0.12 11.9 0.0 0.34 10.3 0.0 1.6 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus HTH_32 PF13565.6 KXS98409.1 - 5.6e-05 23.7 0.9 5.6e-05 23.7 0.9 5.5 7 0 0 7 7 7 1 Homeodomain-like domain HTH_36 PF13730.6 KXS98409.1 - 0.00048 20.0 0.1 0.0016 18.3 0.1 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 KXS98409.1 - 0.002 18.1 0.6 0.002 18.1 0.6 3.3 4 0 0 4 4 4 1 Winged helix-turn helix IQ PF00612.27 KXS98409.1 - 0.011 15.5 0.3 0.038 13.8 0.3 2.1 1 0 0 1 1 1 0 IQ calmodulin-binding motif CENP-B_dimeris PF09026.10 KXS98409.1 - 0.6 10.5 4.9 0.58 10.6 0.2 3.0 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Transp_cyt_pur PF02133.15 KXS98410.1 - 2.2e-84 283.8 34.7 2.2e-84 283.8 34.7 1.3 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin zf-RING_2 PF13639.6 KXS98412.1 - 1.4e-11 44.5 9.2 2.2e-11 43.9 9.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KXS98412.1 - 1.4e-09 38.1 6.9 2.7e-09 37.1 6.9 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KXS98412.1 - 7e-07 29.0 8.6 1.1e-06 28.3 8.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS98412.1 - 1.8e-06 27.7 8.6 2.9e-06 27.1 8.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXS98412.1 - 5.2e-06 26.1 6.4 9.4e-06 25.3 6.4 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 KXS98412.1 - 4.1e-05 23.5 2.2 7.7e-05 22.7 2.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 KXS98412.1 - 0.00012 22.0 3.1 0.00029 20.8 3.1 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KXS98412.1 - 0.00026 20.9 8.0 0.00041 20.2 8.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KXS98412.1 - 0.00079 19.2 6.2 0.0014 18.4 6.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KXS98412.1 - 0.0018 18.1 6.5 0.0029 17.4 6.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KXS98412.1 - 0.0018 17.8 6.5 0.0032 17.1 6.5 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 KXS98412.1 - 0.052 13.4 3.5 0.1 12.5 3.5 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3H2C3 PF17122.5 KXS98412.1 - 0.082 13.0 1.3 0.16 12.0 1.3 1.4 1 0 0 1 1 1 0 Zinc-finger RINGv PF12906.7 KXS98412.1 - 0.1 12.7 9.1 0.18 12.0 9.1 1.4 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 KXS98412.1 - 0.37 11.0 6.7 0.95 9.7 6.9 1.6 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 KXS98412.1 - 0.75 9.6 6.2 1.5 8.7 6.0 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Mcm10 PF09332.11 KXS98412.1 - 2 7.7 4.7 1.2 8.5 0.3 2.3 2 0 0 2 2 2 0 Mcm10 replication factor zf-RING-like PF08746.11 KXS98412.1 - 5.6 7.4 7.0 10 6.6 7.0 1.4 1 0 0 1 1 1 0 RING-like domain VRR_NUC PF08774.11 KXS98413.1 - 8.2e-22 77.3 0.0 2.2e-21 76.0 0.0 1.7 1 0 0 1 1 1 1 VRR-NUC domain Spo0M PF07070.11 KXS98413.1 - 0.0054 16.3 0.0 0.053 13.1 0.0 2.4 3 0 0 3 3 3 1 SpoOM protein NPR3 PF03666.13 KXS98413.1 - 0.038 12.8 0.3 0.094 11.5 0.3 1.6 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 zf-HC5HC2H_2 PF13832.6 KXS98414.1 - 6.7e-18 64.9 3.1 6.7e-18 64.9 3.1 4.0 4 0 0 4 4 4 1 PHD-zinc-finger like domain BAH PF01426.18 KXS98414.1 - 1.6e-15 57.0 0.1 3.8e-15 55.8 0.1 1.7 1 0 0 1 1 1 1 BAH domain zf-HC5HC2H PF13771.6 KXS98414.1 - 8.1e-15 54.9 2.8 8.1e-15 54.9 2.8 4.4 4 0 0 4 4 4 2 PHD-like zinc-binding domain PHD PF00628.29 KXS98414.1 - 4.9e-11 42.3 57.0 2.1e-06 27.5 8.6 6.1 6 0 0 6 6 6 4 PHD-finger PHD_2 PF13831.6 KXS98414.1 - 3.4e-05 23.3 4.8 3.4e-05 23.3 4.8 5.8 5 0 0 5 5 5 1 PHD-finger PHD_4 PF16866.5 KXS98414.1 - 0.055 13.6 35.5 0.22 11.6 2.0 6.4 6 0 0 6 6 6 0 PHD-finger GATA PF00320.27 KXS98414.1 - 0.58 9.8 15.0 0.21 11.2 1.6 3.8 3 0 0 3 3 3 0 GATA zinc finger AFG1_ATPase PF03969.16 KXS98415.1 - 1.1e-91 307.5 0.0 5.1e-87 292.1 0.0 2.3 2 0 0 2 2 2 2 AFG1-like ATPase AAA_14 PF13173.6 KXS98415.1 - 0.00059 19.9 0.0 0.0014 18.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KXS98415.1 - 0.0057 16.9 0.0 0.075 13.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KXS98415.1 - 0.0069 16.8 0.2 3.1 8.2 0.0 3.2 3 2 0 4 4 4 1 AAA ATPase domain RNA_helicase PF00910.22 KXS98415.1 - 0.028 14.8 1.9 0.078 13.4 0.2 2.6 2 1 0 2 2 2 0 RNA helicase APS_kinase PF01583.20 KXS98415.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA PF00004.29 KXS98415.1 - 0.21 12.0 0.4 0.6 10.5 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SNF PF00209.18 KXS98416.1 - 7.9e-73 245.9 36.9 1.7e-45 155.7 19.5 3.0 3 0 0 3 3 3 3 Sodium:neurotransmitter symporter family DUF3328 PF11807.8 KXS98423.1 - 4.6e-23 82.1 0.0 4.7e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3659 PF12396.8 KXS98424.1 - 0 1181.4 229.8 1.3e-21 76.3 0.1 20.7 22 0 0 22 22 22 19 Protein of unknown function (DUF3659) GCV_T_C PF08669.11 KXS98424.1 - 1.4e-05 24.9 5.5 11 6.0 0.0 8.5 9 1 1 10 10 10 2 Glycine cleavage T-protein C-terminal barrel domain RPW8 PF05659.11 KXS98424.1 - 0.37 10.5 2.7 2.5 7.8 0.8 2.3 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF883 PF05957.13 KXS98424.1 - 3 8.5 52.3 0.061 13.9 2.2 8.2 9 0 0 9 9 9 0 Bacterial protein of unknown function (DUF883) Amidase PF01425.21 KXS98425.1 - 3.5e-98 329.5 0.0 4e-98 329.3 0.0 1.0 1 0 0 1 1 1 1 Amidase DUF1776 PF08643.10 KXS98426.1 - 2e-60 204.7 0.0 2.4e-53 181.4 0.0 2.1 1 1 1 2 2 2 2 Fungal family of unknown function (DUF1776) adh_short PF00106.25 KXS98426.1 - 7.7e-07 28.8 0.0 1.6e-06 27.7 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS98426.1 - 0.00045 19.8 0.0 0.0011 18.5 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase DUF3328 PF11807.8 KXS98427.1 - 1.9e-31 109.6 0.0 2.5e-31 109.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DLH PF01738.18 KXS98429.1 - 2.4e-17 63.3 0.7 2.9e-17 62.9 0.7 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Aminotran_3 PF00202.21 KXS98430.1 - 1.5e-87 293.9 0.0 1.9e-87 293.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Bac_rhamnosid6H PF17389.2 KXS98431.1 - 1.6e-69 234.8 0.1 2.4e-69 234.2 0.1 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 KXS98431.1 - 1.3e-37 129.2 0.0 3.6e-37 127.8 0.0 1.7 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 KXS98431.1 - 5.8e-18 64.7 0.1 2.1e-17 62.9 0.0 1.9 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 KXS98431.1 - 5.5e-14 51.7 0.0 1.5e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain DNA_ligase_OB PF03120.16 KXS98431.1 - 0.078 12.9 0.1 0.19 11.6 0.1 1.7 1 0 0 1 1 1 0 NAD-dependent DNA ligase OB-fold domain E1_DerP2_DerF2 PF02221.15 KXS98433.1 - 1.6e-14 54.5 0.0 1.9e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 ML domain Dus PF01207.17 KXS98434.1 - 2.3e-46 158.3 0.1 1.3e-45 155.8 0.1 2.0 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Radical_SAM PF04055.21 KXS98434.1 - 0.068 13.5 0.0 2.3 8.6 0.0 2.4 1 1 0 1 1 1 0 Radical SAM superfamily PucR PF07905.11 KXS98434.1 - 0.077 13.3 0.0 0.6 10.4 0.0 2.4 1 1 1 2 2 2 0 Purine catabolism regulatory protein-like family Gluconate_2-dh3 PF13618.6 KXS98434.1 - 0.078 13.2 0.0 0.58 10.4 0.0 2.4 1 1 1 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 DUF3328 PF11807.8 KXS98435.1 - 1.8e-30 106.3 0.1 2.8e-30 105.7 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) LigB PF02900.18 KXS98436.1 - 1.3e-23 83.5 0.0 2.2e-23 82.7 0.0 1.4 1 1 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase pPIWI_RE_REase PF18154.1 KXS98437.1 - 6.2e-07 29.4 0.1 1.4 8.9 0.0 4.6 1 1 3 5 5 5 3 REase associating with pPIWI_RE Kelch_3 PF13415.6 KXS98437.1 - 0.024 14.9 2.8 38 4.7 0.1 3.3 3 0 0 3 3 3 0 Galactose oxidase, central domain SpuA_C PF18033.1 KXS98437.1 - 0.031 14.3 0.9 70 3.6 0.0 4.0 1 1 2 4 4 4 0 SpuA C-terminal Tombus_movement PF05318.12 KXS98437.1 - 0.051 14.4 25.6 13 6.7 0.2 6.2 3 2 3 6 6 6 0 Tombusvirus movement protein NTase_sub_bind PF08780.11 KXS98437.1 - 3.2 7.7 20.1 59 3.6 0.0 6.8 2 2 6 8 8 8 0 Nucleotidyltransferase substrate binding protein like Arginosuc_synth PF00764.19 KXS98448.1 - 6.6e-157 522.8 0.0 7.6e-157 522.6 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 KXS98448.1 - 0.023 14.2 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 KXS98448.1 - 0.031 13.1 0.0 0.044 12.6 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase Beta-lactamase PF00144.24 KXS98449.1 - 2.5e-34 119.0 0.0 3.5e-34 118.5 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 KXS98449.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Ndc80_HEC PF03801.13 KXS98450.1 - 1.5e-56 190.2 0.2 3e-56 189.3 0.2 1.5 1 0 0 1 1 1 1 HEC/Ndc80p family MukB PF04310.12 KXS98450.1 - 0.012 15.4 0.0 0.012 15.4 0.0 3.0 3 0 0 3 3 3 0 MukB N-terminal Filament PF00038.21 KXS98450.1 - 0.23 11.0 55.3 0.052 13.1 19.0 4.1 2 2 2 4 4 4 0 Intermediate filament protein adh_short_C2 PF13561.6 KXS98450.1 - 1.1 8.8 5.1 4.3 6.8 0.2 2.3 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase Phage_GP20 PF06810.11 KXS98450.1 - 1.1 9.1 39.1 0.41 10.4 8.0 4.0 2 2 1 3 3 3 0 Phage minor structural protein GP20 NPV_P10 PF05531.12 KXS98450.1 - 2.9 8.4 12.0 7.7 7.1 1.0 4.1 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF16 PF01519.16 KXS98450.1 - 6.3 7.3 33.5 0.072 13.6 6.8 4.2 2 2 2 4 4 4 0 Protein of unknown function DUF16 Spc7 PF08317.11 KXS98450.1 - 9.6 5.0 58.0 0.37 9.6 26.4 3.3 2 2 1 3 3 3 0 Spc7 kinetochore protein DUF812 PF05667.11 KXS98450.1 - 9.8 4.9 44.9 0.21 10.4 20.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Methyltransf_25 PF13649.6 KXS98451.1 - 1.5e-10 41.7 0.0 6.2e-10 39.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 KXS98451.1 - 1.8e-09 37.4 0.0 2.9e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 KXS98451.1 - 9.1e-09 35.3 0.0 2.1e-08 34.1 0.0 1.6 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS98451.1 - 1.8e-07 31.7 0.0 9e-07 29.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 KXS98451.1 - 4.7e-06 25.8 0.1 7e-06 25.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 KXS98451.1 - 0.00019 20.9 0.0 0.00031 20.1 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 KXS98451.1 - 0.00053 19.9 0.0 0.00089 19.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXS98451.1 - 0.0007 19.5 0.0 0.0011 18.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS98451.1 - 0.0047 17.6 0.0 0.012 16.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KXS98451.1 - 0.022 14.3 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 KXS98451.1 - 0.045 13.7 0.0 0.08 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Oxidored_FMN PF00724.20 KXS98452.1 - 9.3e-98 327.6 0.0 1.1e-97 327.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Glycos_trans_3N PF02885.17 KXS98452.1 - 0.11 12.4 0.0 3.3 7.6 0.1 2.3 2 0 0 2 2 2 0 Glycosyl transferase family, helical bundle domain TA_inhibitor PF17574.2 KXS98452.1 - 0.24 11.4 0.6 6.9 6.8 0.1 2.6 2 1 1 3 3 3 0 Inhibitor of toxin/antitoxin system (Gp4.5) Snf7 PF03357.21 KXS98453.1 - 8.5e-14 51.5 13.1 1e-13 51.3 13.1 1.1 1 0 0 1 1 1 1 Snf7 DMSP_lyase PF16867.5 KXS98453.1 - 0.0052 16.4 0.4 0.011 15.4 0.0 1.7 2 0 0 2 2 2 1 Dimethlysulfonioproprionate lyase Ist1 PF03398.14 KXS98453.1 - 0.011 15.6 5.1 0.02 14.8 5.1 1.3 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway Vps51 PF08700.11 KXS98453.1 - 4.4 7.4 9.8 1.2 9.2 4.8 2.5 2 1 1 3 3 3 0 Vps51/Vps67 DUF724 PF05266.14 KXS98453.1 - 5.1 6.9 8.9 17 5.2 6.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) MS_channel PF00924.18 KXS98454.1 - 8.1e-18 64.7 1.7 1.5e-17 63.8 1.7 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 KXS98454.1 - 0.0038 16.7 0.1 0.01 15.3 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXS98454.1 - 0.055 13.4 0.0 0.055 13.4 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.6 KXS98454.1 - 0.1 13.1 0.1 0.27 11.7 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain pair Amidase PF01425.21 KXS98456.1 - 4.7e-96 322.5 0.0 5.4e-96 322.3 0.0 1.0 1 0 0 1 1 1 1 Amidase DUF3483 PF11982.8 KXS98457.1 - 0.087 12.4 0.4 2.9 7.5 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3483) PI3_PI4_kinase PF00454.27 KXS98458.1 - 3.2e-54 184.4 0.0 7e-54 183.3 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 KXS98458.1 - 5.2e-31 108.1 3.1 1.3e-30 106.8 3.1 1.8 1 0 0 1 1 1 1 FAT domain UME PF08064.13 KXS98458.1 - 1e-25 89.6 0.0 7.7e-25 86.8 0.0 2.7 2 0 0 2 2 2 1 UME (NUC010) domain FATC PF02260.20 KXS98458.1 - 3.3e-14 52.4 0.0 7.5e-14 51.3 0.0 1.7 1 0 0 1 1 1 1 FATC domain DUF3385 PF11865.8 KXS98458.1 - 0.12 12.2 0.0 1 9.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) TPR_19 PF14559.6 KXS98458.1 - 0.28 11.7 3.3 0.9 10.1 0.5 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXS98458.1 - 5.5 8.1 6.7 99 4.2 0.1 5.2 3 0 0 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 KXS98458.1 - 5.6 7.4 15.5 0.91 9.9 0.2 4.2 4 0 0 4 4 4 0 Bacterial transcriptional activator domain Abhydrolase_3 PF07859.13 KXS98459.1 - 2e-44 152.0 0.0 1.3e-33 116.6 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 KXS98459.1 - 4.6e-09 35.7 0.1 1.2e-08 34.3 0.1 1.6 1 1 0 1 1 1 1 Carboxylesterase family Chlorophyllase2 PF12740.7 KXS98459.1 - 0.026 13.4 0.0 0.04 12.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF2974 PF11187.8 KXS98459.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF829 PF05705.14 KXS98459.1 - 0.16 11.8 0.0 20 4.9 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF829) Abhydrolase_2 PF02230.16 KXS98459.1 - 0.25 11.1 0.0 0.53 10.0 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase YL1_C PF08265.11 KXS98460.1 - 2.5e-16 59.1 2.4 4.4e-16 58.3 2.4 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain BMC PF00936.19 KXS98461.1 - 0.15 12.1 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 BMC domain DOT1 PF08123.13 KXS98462.1 - 2.1e-40 138.5 0.0 2.7e-40 138.1 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_23 PF13489.6 KXS98462.1 - 0.017 15.0 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 KXS98462.1 - 0.12 12.1 0.0 0.27 10.9 0.0 1.5 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) AA_permease_2 PF13520.6 KXS98463.1 - 4e-84 282.9 32.5 5.1e-84 282.6 32.5 1.1 1 0 0 1 1 1 1 Amino acid permease F-box-like PF12937.7 KXS98463.1 - 0.021 14.7 0.2 0.14 12.0 0.3 2.3 2 0 0 2 2 2 0 F-box-like PAP_assoc PF03828.19 KXS98464.1 - 1.6e-20 73.1 0.0 4.9e-20 71.5 0.0 1.9 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KXS98464.1 - 3e-06 27.4 0.0 7e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KXS98464.1 - 0.0034 17.4 0.0 0.0078 16.3 0.0 1.5 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase CAF20 PF17052.5 KXS98464.1 - 0.02 15.0 2.4 0.063 13.4 2.4 1.9 1 0 0 1 1 1 0 Cap associated factor F-box PF00646.33 KXS98465.1 - 0.00039 20.2 0.1 0.00069 19.4 0.1 1.4 1 0 0 1 1 1 1 F-box domain AAL_decarboxy PF03306.13 KXS98465.1 - 0.0097 15.3 0.1 0.013 14.8 0.1 1.2 1 0 0 1 1 1 1 Alpha-acetolactate decarboxylase p450 PF00067.22 KXS98466.1 - 1.9e-64 218.1 0.0 2.3e-64 217.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Longin PF13774.6 KXS98467.1 - 4.8e-16 58.6 0.1 3.2e-15 55.9 0.0 2.3 3 0 0 3 3 3 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 KXS98467.1 - 8.8e-14 51.1 0.2 2e-13 49.9 0.2 1.6 1 0 0 1 1 1 1 Synaptobrevin F-box PF00646.33 KXS98467.1 - 0.00027 20.7 0.0 0.00082 19.2 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXS98467.1 - 0.063 13.2 0.0 0.22 11.4 0.0 1.9 2 0 0 2 2 2 0 F-box-like DUF1786 PF08735.10 KXS98468.1 - 0.13 11.6 0.0 0.24 10.6 0.0 1.4 1 1 0 1 1 1 0 Putative pyruvate format-lyase activating enzyme (DUF1786) SAP PF02037.27 KXS98470.1 - 0.03 14.1 2.2 0.049 13.4 0.4 2.4 2 1 0 2 2 2 0 SAP domain Nic96 PF04097.14 KXS98471.1 - 1.9e-206 687.3 1.0 2.4e-206 687.0 1.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Pex14_N PF04695.13 KXS98472.1 - 9.3e-26 91.4 9.5 9.3e-26 91.4 9.5 3.6 2 2 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region ERM PF00769.19 KXS98472.1 - 0.00033 20.5 3.6 0.00079 19.3 3.6 1.6 1 0 0 1 1 1 1 Ezrin/radixin/moesin family GrpE PF01025.19 KXS98472.1 - 0.00056 19.6 4.9 0.00099 18.8 4.9 1.3 1 0 0 1 1 1 1 GrpE DUF1043 PF06295.12 KXS98472.1 - 0.034 14.1 0.4 0.085 12.9 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF4235 PF14019.6 KXS98472.1 - 0.051 13.7 0.7 4.1 7.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4235) UPF0242 PF06785.11 KXS98472.1 - 0.061 13.4 0.2 0.11 12.6 0.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF3584 PF12128.8 KXS98472.1 - 0.22 9.0 5.8 0.31 8.5 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SOG2 PF10428.9 KXS98472.1 - 1.9 7.6 9.2 2.9 7.0 9.2 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein DUF4164 PF13747.6 KXS98472.1 - 1.9 8.8 12.1 0.22 11.8 1.5 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) ZapB PF06005.12 KXS98472.1 - 4.9 7.7 10.3 4.7 7.7 4.2 2.6 1 1 1 2 2 2 0 Cell division protein ZapB Fungal_trans_2 PF11951.8 KXS98473.1 - 1.1e-15 57.4 0.1 1.5e-15 56.9 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS98473.1 - 0.00014 21.9 6.6 0.00026 21.0 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box PF00646.33 KXS98474.1 - 3.8e-05 23.5 0.0 0.00011 21.9 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXS98474.1 - 0.00088 19.1 0.2 0.0017 18.2 0.2 1.6 1 0 0 1 1 1 1 F-box-like AAA_12 PF13087.6 KXS98475.1 - 3.4e-23 82.3 0.0 6.1e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KXS98475.1 - 2e-11 44.2 0.0 4.7e-11 43.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXS98475.1 - 2.1e-09 37.4 0.0 1.1e-05 25.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KXS98475.1 - 0.00017 22.0 0.0 0.00085 19.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 KXS98475.1 - 0.0002 21.4 0.0 0.00056 19.9 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 KXS98475.1 - 0.00027 21.4 0.0 0.00098 19.5 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 KXS98475.1 - 0.0015 19.0 0.0 0.0031 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KXS98475.1 - 0.0095 16.2 0.0 0.027 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KXS98475.1 - 0.016 15.6 0.0 0.048 14.1 0.0 1.8 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KXS98475.1 - 0.02 13.9 0.0 0.042 12.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein UvrD_C_2 PF13538.6 KXS98475.1 - 0.03 14.1 0.0 0.12 12.3 0.0 2.1 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain PIF1 PF05970.14 KXS98475.1 - 0.043 13.0 0.0 0.075 12.2 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase PhoH PF02562.16 KXS98475.1 - 0.045 13.2 0.0 0.096 12.1 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Viral_helicase1 PF01443.18 KXS98475.1 - 0.063 13.0 0.0 35 4.0 0.0 3.3 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 KXS98475.1 - 0.064 13.0 0.0 0.21 11.4 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 KXS98475.1 - 0.19 11.3 0.4 2.1 7.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region MTHFR PF02219.17 KXS98476.1 - 6.7e-111 370.2 0.0 1e-110 369.6 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase adh_short_C2 PF13561.6 KXS98476.1 - 3.9e-43 147.7 0.1 6.1e-43 147.0 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS98476.1 - 2.4e-40 138.1 1.0 4e-40 137.4 1.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS98476.1 - 3e-13 50.1 0.7 5.4e-13 49.2 0.7 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS98476.1 - 0.026 14.0 0.3 0.63 9.5 0.2 2.9 3 1 0 3 3 3 0 NAD dependent epimerase/dehydratase family DUF1614 PF07758.11 KXS98476.1 - 0.069 13.2 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1614) Fungal_lectin PF07938.12 KXS98477.1 - 1.8e-05 24.3 0.0 2.9e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Fungal fucose-specific lectin Zn_clus PF00172.18 KXS98477.1 - 0.014 15.5 6.4 0.29 11.3 1.2 2.3 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain KH_8 PF17903.1 KXS98478.1 - 4.4e-31 106.8 0.0 1.1e-30 105.6 0.0 1.7 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 KXS98478.1 - 0.009 15.8 0.1 0.024 14.5 0.1 1.8 1 0 0 1 1 1 1 KH domain QVR PF17064.5 KXS98479.1 - 0.14 12.4 0.1 0.26 11.6 0.1 1.4 1 0 0 1 1 1 0 Sleepless protein MraZ PF02381.18 KXS98481.1 - 0.27 11.3 1.6 0.45 10.5 0.1 2.1 2 1 0 2 2 2 0 MraZ protein, putative antitoxin-like OsmC PF02566.19 KXS98482.1 - 7.1e-15 55.3 0.1 2.4e-14 53.6 0.0 1.7 2 0 0 2 2 2 1 OsmC-like protein Dak2 PF02734.17 KXS98483.1 - 4.6e-42 143.8 1.0 1.3e-41 142.4 0.1 2.0 2 0 0 2 2 2 1 DAK2 domain DUF881 PF05949.12 KXS98483.1 - 0.019 14.8 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF881) FAD_binding_2 PF00890.24 KXS98484.1 - 1.3e-119 400.1 4.4 1.6e-119 399.7 4.4 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 KXS98484.1 - 4.4e-41 139.9 1.4 6.7e-41 139.3 1.4 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 KXS98484.1 - 6.5e-05 22.3 1.7 0.0016 17.8 0.7 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXS98484.1 - 0.00012 21.3 3.2 0.017 14.2 2.5 2.5 3 0 0 3 3 3 2 Glucose inhibited division protein A Thi4 PF01946.17 KXS98484.1 - 0.0011 18.2 0.3 0.08 12.2 0.1 2.4 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 KXS98484.1 - 0.0034 16.7 0.5 0.0061 15.8 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KXS98484.1 - 0.045 12.4 4.5 0.25 10.0 0.7 2.6 3 0 0 3 3 3 0 HI0933-like protein DAO PF01266.24 KXS98484.1 - 0.046 13.3 0.7 0.078 12.5 0.7 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KXS98484.1 - 0.12 11.4 0.1 0.19 10.8 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KXS98484.1 - 2 7.6 3.4 2 7.6 1.7 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXS98485.1 - 1.3e-119 400.1 4.4 1.6e-119 399.7 4.4 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 KXS98485.1 - 4.4e-41 139.9 1.4 6.7e-41 139.3 1.4 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 KXS98485.1 - 6.5e-05 22.3 1.7 0.0016 17.8 0.7 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXS98485.1 - 0.00012 21.3 3.2 0.017 14.2 2.5 2.5 3 0 0 3 3 3 2 Glucose inhibited division protein A Thi4 PF01946.17 KXS98485.1 - 0.0011 18.2 0.3 0.08 12.2 0.1 2.4 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 KXS98485.1 - 0.0034 16.7 0.5 0.0061 15.8 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KXS98485.1 - 0.045 12.4 4.5 0.25 10.0 0.7 2.6 3 0 0 3 3 3 0 HI0933-like protein DAO PF01266.24 KXS98485.1 - 0.046 13.3 0.7 0.078 12.5 0.7 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KXS98485.1 - 0.12 11.4 0.1 0.19 10.8 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KXS98485.1 - 2 7.6 3.4 2 7.6 1.7 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Alpha-L-AF_C PF06964.12 KXS98487.1 - 3.3e-20 72.9 0.0 5.6e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain CBM_4_9 PF02018.17 KXS98487.1 - 0.0038 17.5 1.4 0.0059 16.9 0.4 1.8 2 0 0 2 2 2 1 Carbohydrate binding domain Fungal_trans_2 PF11951.8 KXS98488.1 - 1.2e-13 50.7 9.3 2.6e-13 49.5 9.3 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS98488.1 - 4.6e-06 26.7 11.6 8.9e-06 25.7 11.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Clusterin PF01093.17 KXS98488.1 - 0.13 11.2 1.2 0.22 10.5 1.2 1.3 1 0 0 1 1 1 0 Clusterin Dickkopf_N PF04706.12 KXS98488.1 - 0.66 10.5 9.0 1.8 9.1 9.0 1.7 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Fungal_trans PF04082.18 KXS98489.1 - 3.7e-12 45.8 0.1 9.9e-12 44.4 0.1 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 KXS98489.1 - 2.8e-06 27.5 10.6 5.4e-05 23.4 3.5 2.8 2 0 0 2 2 2 2 Zinc-finger double domain zf-Di19 PF05605.12 KXS98489.1 - 0.0007 19.8 5.4 0.0016 18.7 5.4 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KXS98489.1 - 0.0012 19.5 17.1 0.041 14.7 5.6 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KXS98489.1 - 0.08 13.4 16.8 0.27 11.8 7.1 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KXS98489.1 - 0.12 12.7 6.8 0.18 12.1 1.2 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXS98489.1 - 9.3 6.8 6.7 9.6 6.8 0.8 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Transketolase_N PF00456.21 KXS98491.1 - 2e-125 418.2 0.0 3.2e-125 417.5 0.0 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KXS98491.1 - 1.3e-31 109.6 0.0 6.2e-31 107.4 0.0 1.9 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KXS98491.1 - 6.8e-06 26.0 0.0 1.5e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.20 KXS98491.1 - 9.1e-05 21.5 0.0 0.00015 20.8 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KXS98491.1 - 0.00045 19.5 0.0 0.0035 16.6 0.0 2.3 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase SR-25 PF10500.9 KXS98492.1 - 0.037 13.6 21.2 0.015 14.9 17.1 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Apt1 PF10351.9 KXS98492.1 - 0.11 11.3 6.5 0.18 10.6 6.5 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain RAP1 PF07218.11 KXS98492.1 - 2.9 6.0 10.4 5.3 5.2 10.4 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) UL42 PF17638.2 KXS98492.1 - 7.1 6.6 8.1 0.91 9.5 1.6 2.3 2 0 0 2 2 2 0 HCMV UL42 SR-25 PF10500.9 KXS98493.1 - 0.049 13.2 21.7 0.022 14.4 17.6 2.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Apt1 PF10351.9 KXS98493.1 - 0.11 11.3 6.5 0.18 10.6 6.5 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain RAP1 PF07218.11 KXS98493.1 - 3 6.0 10.4 5.4 5.2 10.4 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) UL42 PF17638.2 KXS98493.1 - 7.3 6.6 8.1 0.92 9.5 1.6 2.3 2 0 0 2 2 2 0 HCMV UL42 SR-25 PF10500.9 KXS98494.1 - 0.037 13.6 21.2 0.015 14.9 17.1 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Apt1 PF10351.9 KXS98494.1 - 0.11 11.3 6.5 0.18 10.6 6.5 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain RAP1 PF07218.11 KXS98494.1 - 2.9 6.0 10.4 5.3 5.2 10.4 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) UL42 PF17638.2 KXS98494.1 - 7.1 6.6 8.1 0.91 9.5 1.6 2.3 2 0 0 2 2 2 0 HCMV UL42 NAD_binding_11 PF14833.6 KXS98495.1 - 2.6e-41 140.7 0.5 1.5e-27 96.3 0.2 2.4 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 KXS98495.1 - 2.3e-37 128.6 0.0 4.3e-37 127.7 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 KXS98495.1 - 0.0022 17.4 0.0 0.0044 16.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KXS98495.1 - 0.0032 18.0 0.0 0.0088 16.6 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh PF00984.19 KXS98495.1 - 0.0036 17.5 0.2 0.44 10.8 0.1 2.9 2 1 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain 3HCDH_N PF02737.18 KXS98495.1 - 0.018 15.0 1.1 0.037 13.9 0.1 2.1 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KXS98495.1 - 0.14 11.7 0.0 12 5.4 0.1 2.7 2 1 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain LANC_like PF05147.13 KXS98496.1 - 1.2e-29 103.0 0.0 1.8e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein Pec_lyase PF09492.10 KXS98496.1 - 0.058 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Pectic acid lyase FA_desaturase PF00487.24 KXS98497.1 - 5.7e-18 65.7 17.9 1.1e-17 64.8 17.9 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KXS98497.1 - 9.2e-17 61.0 0.1 1.9e-16 59.9 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain BIR PF00653.21 KXS98498.1 - 0.034 14.8 0.0 0.076 13.7 0.0 1.6 1 0 0 1 1 1 0 Inhibitor of Apoptosis domain NOT2_3_5 PF04153.18 KXS98499.1 - 9.1e-26 90.5 0.5 9.1e-26 90.5 0.5 1.8 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family DUF2271 PF10029.9 KXS98499.1 - 0.017 14.7 0.2 0.031 13.9 0.2 1.3 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2271) NOT2_3_5 PF04153.18 KXS98500.1 - 8.6e-26 90.6 0.5 8.6e-26 90.6 0.5 1.8 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family DUF2271 PF10029.9 KXS98500.1 - 0.016 14.9 0.1 0.028 14.0 0.1 1.3 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2271) NOT2_3_5 PF04153.18 KXS98501.1 - 8.8e-26 90.5 0.5 8.8e-26 90.5 0.5 1.8 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family DUF2271 PF10029.9 KXS98501.1 - 0.017 14.8 0.2 0.03 14.0 0.2 1.3 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2271) UBA_4 PF14555.6 KXS98502.1 - 0.017 14.9 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain V-SNARE_C PF12352.8 KXS98503.1 - 0.013 15.8 7.4 0.11 12.8 1.8 3.3 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus DUF5089 PF17002.5 KXS98503.1 - 0.096 12.5 19.0 13 5.6 19.0 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5089) Pro-kuma_activ PF09286.11 KXS98504.1 - 4.5e-41 140.5 0.5 5.2e-40 137.0 0.5 2.2 1 1 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KXS98504.1 - 9.3e-06 25.1 0.4 1.8e-05 24.2 0.4 1.4 1 0 0 1 1 1 1 Subtilase family RSRP PF17069.5 KXS98505.1 - 0.065 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 TRI12 PF06609.13 KXS98507.1 - 2.4e-36 125.4 29.4 3.1e-36 125.0 29.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KXS98507.1 - 1.9e-25 89.5 48.0 1.9e-25 89.5 48.0 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS98507.1 - 8.3e-15 54.6 7.3 8.3e-15 54.6 7.3 3.3 3 1 1 4 4 4 1 Sugar (and other) transporter Cation_ATPase_C PF00689.21 KXS98507.1 - 0.43 10.3 23.8 0.049 13.3 7.1 4.2 3 1 0 4 4 4 0 Cation transporting ATPase, C-terminus DUF2614 PF11023.8 KXS98507.1 - 9.2 6.4 11.6 0.085 13.0 0.9 3.0 3 0 0 3 3 3 0 Zinc-ribbon containing domain zf-FPG_IleRS PF06827.14 KXS98508.1 - 0.19 11.7 3.8 0.097 12.5 0.7 2.1 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS ERAP1_C PF11838.8 KXS98509.1 - 7.7e-92 308.2 2.1 1.7e-90 303.8 0.9 2.4 2 0 0 2 2 2 2 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 KXS98509.1 - 2e-85 285.8 0.5 3.3e-85 285.1 0.5 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KXS98509.1 - 2.8e-53 180.9 0.9 8.5e-53 179.3 0.6 1.9 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Zn_clus PF00172.18 KXS98510.1 - 2.4e-07 30.8 10.9 4.7e-07 29.8 10.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Toxin_6 PF05453.12 KXS98511.1 - 3.9 8.0 7.7 0.33 11.4 2.4 2.0 2 0 0 2 2 2 0 BmTXKS1/BmP02 toxin family Sporozoite_P67 PF05642.11 KXS98511.1 - 5 5.1 9.4 5.5 4.9 9.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen adh_short PF00106.25 KXS98512.1 - 6.4e-25 87.8 0.0 7.9e-25 87.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS98512.1 - 9.9e-14 51.5 0.0 1.3e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Pro_isomerase PF00160.21 KXS98513.1 - 8.7e-49 165.8 0.8 1.6e-48 164.9 0.3 1.8 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 KXS98513.1 - 2.8e-13 50.1 0.1 0.0036 18.1 0.0 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS98513.1 - 0.00042 20.6 0.0 0.025 14.8 0.0 3.3 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXS98513.1 - 0.0036 16.3 0.3 2.2 7.2 0.1 2.6 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Glyco_hydro_47 PF01532.20 KXS98514.1 - 1.6e-126 422.9 0.0 2e-126 422.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 HlyIII PF03006.20 KXS98515.1 - 1.6e-60 204.6 19.6 2e-60 204.3 19.6 1.1 1 0 0 1 1 1 1 Haemolysin-III related YabA PF06156.13 KXS98515.1 - 0.056 14.1 0.2 0.13 13.0 0.2 1.5 1 0 0 1 1 1 0 Initiation control protein YabA CENP-H PF05837.12 KXS98515.1 - 0.12 12.8 2.0 0.14 12.6 0.9 1.7 1 1 0 1 1 1 0 Centromere protein H (CENP-H) G_glu_transpept PF01019.21 KXS98518.1 - 7.2e-163 543.0 0.1 8.7e-163 542.8 0.1 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase CN_hydrolase PF00795.22 KXS98519.1 - 9.4e-30 103.8 0.0 1.3e-29 103.3 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 KXS98519.1 - 1.4e-24 86.6 0.0 4.8e-24 84.8 0.0 1.7 1 1 0 1 1 1 1 NAD synthase ApoL PF05461.11 KXS98519.1 - 0.0063 15.9 0.1 0.01 15.2 0.1 1.2 1 0 0 1 1 1 1 Apolipoprotein L A_deaminase PF00962.22 KXS98520.1 - 3.8e-31 108.6 0.0 4.6e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase DUF1749 PF08538.10 KXS98521.1 - 4.4e-76 255.8 0.0 4.9e-76 255.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Hydrolase_4 PF12146.8 KXS98521.1 - 1.1e-08 34.7 0.0 4.6e-08 32.6 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXS98521.1 - 1.7e-07 32.1 0.0 2.1e-07 31.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.12 KXS98521.1 - 0.00012 21.7 0.0 0.00018 21.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_1 PF00561.20 KXS98521.1 - 0.0044 16.7 0.0 0.007 16.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 KXS98521.1 - 0.0061 16.4 0.0 0.016 15.1 0.0 1.6 1 1 1 2 2 2 1 Serine hydrolase Cutinase PF01083.22 KXS98521.1 - 0.014 15.4 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 Cutinase DUF915 PF06028.11 KXS98521.1 - 0.068 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Chlorophyllase2 PF12740.7 KXS98521.1 - 0.11 11.3 0.0 0.22 10.4 0.0 1.4 1 1 0 1 1 1 0 Chlorophyllase enzyme MS_channel PF00924.18 KXS98523.1 - 2.3e-09 37.1 0.3 4.8e-09 36.1 0.3 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 KXS98523.1 - 0.0057 16.1 0.2 0.017 14.6 0.2 1.9 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KXS98523.1 - 0.016 15.6 0.0 0.055 13.9 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair Exo70 PF03081.15 KXS98523.1 - 0.04 13.0 0.1 0.068 12.2 0.1 1.3 1 0 0 1 1 1 0 Exo70 exocyst complex subunit EF-hand_6 PF13405.6 KXS98523.1 - 0.048 13.6 0.4 0.45 10.6 0.1 2.7 3 0 0 3 3 3 0 EF-hand domain EF-hand_8 PF13833.6 KXS98523.1 - 0.13 12.1 0.7 0.33 10.9 0.7 1.6 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.6 KXS98523.1 - 0.2 11.2 0.5 1.6 8.3 0.2 2.4 2 0 0 2 2 2 0 EF hand DUF2976 PF11190.8 KXS98523.1 - 0.86 9.4 0.0 0.86 9.4 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) DUF3810 PF12725.7 KXS98523.1 - 5 6.4 13.9 1 8.7 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3810) SWIB PF02201.18 KXS98526.1 - 2.7e-31 107.2 0.3 6e-31 106.2 0.3 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 KXS98526.1 - 1.5e-13 50.4 3.6 1.5e-13 50.4 1.3 2.2 3 0 0 3 3 3 1 DEK C terminal domain DUF1878 PF08963.10 KXS98526.1 - 0.022 15.2 0.0 0.046 14.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1878) SRP54_N PF02881.19 KXS98526.1 - 0.039 14.2 1.3 0.68 10.2 0.4 2.5 2 0 0 2 2 2 0 SRP54-type protein, helical bundle domain FliT PF05400.13 KXS98526.1 - 0.18 12.6 6.4 2 9.3 1.4 2.5 2 0 0 2 2 2 0 Flagellar protein FliT SAPS PF04499.15 KXS98526.1 - 0.36 9.6 5.6 0.47 9.2 5.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SRP-alpha_N PF04086.13 KXS98526.1 - 0.49 10.3 16.8 0.76 9.6 16.8 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Mso1_C PF14477.6 KXS98526.1 - 7.5 7.0 7.7 1.6 9.2 3.0 2.3 2 0 0 2 2 2 0 Membrane-polarising domain of Mso1 IGR PF09597.10 KXS98528.1 - 5e-23 81.0 0.1 8e-23 80.3 0.1 1.3 1 0 0 1 1 1 1 IGR protein motif HhH-GPD PF00730.25 KXS98529.1 - 8.5e-05 23.0 0.0 0.0002 21.8 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Sugar_tr PF00083.24 KXS98530.1 - 2e-61 208.2 13.9 6.6e-61 206.5 13.9 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS98530.1 - 7.3e-12 44.9 26.8 9.5e-12 44.5 26.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Nuc_H_symport PF03825.16 KXS98530.1 - 1.8e-05 24.0 0.2 1.8e-05 24.0 0.2 2.0 2 0 0 2 2 2 1 Nucleoside H+ symporter Inositol_P PF00459.25 KXS98532.1 - 2.2e-59 201.2 0.0 2.6e-59 201.0 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DUF1772 PF08592.11 KXS98533.1 - 0.018 15.4 4.1 0.023 15.0 3.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) BCD PF15461.6 KXS98533.1 - 0.025 14.1 1.5 0.22 11.0 0.5 2.0 2 0 0 2 2 2 0 Beta-carotene 15,15'-dioxygenase DUF2781 PF10914.8 KXS98533.1 - 0.039 14.4 0.7 0.074 13.5 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) Cation_efflux PF01545.21 KXS98533.1 - 0.042 13.6 2.1 0.14 11.9 2.0 1.9 1 1 0 1 1 1 0 Cation efflux family MARVEL PF01284.23 KXS98533.1 - 0.052 13.6 9.2 0.14 12.1 9.0 1.9 1 1 1 2 2 2 0 Membrane-associating domain SUa-2TM PF18179.1 KXS98533.1 - 0.077 12.3 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 SMODS- and Ubiquitin system-associated 2TM effector domain DUF2157 PF09925.9 KXS98533.1 - 0.21 11.3 3.2 0.43 10.4 2.2 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) Ion_trans PF00520.31 KXS98533.1 - 0.23 10.7 8.8 0.18 11.0 4.8 2.2 2 1 0 2 2 2 0 Ion transport protein DUF3290 PF11694.8 KXS98533.1 - 0.3 11.0 1.9 0.45 10.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) DUF2721 PF11026.8 KXS98533.1 - 0.31 10.9 3.9 12 5.8 2.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) 7TMR-DISM_7TM PF07695.11 KXS98533.1 - 0.34 10.8 7.2 0.043 13.7 2.8 1.6 2 0 0 2 2 2 0 7TM diverse intracellular signalling DUF4381 PF14316.6 KXS98533.1 - 0.94 9.7 3.2 23 5.2 0.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4381) COX1 PF00115.20 KXS98533.1 - 1.1 8.1 6.9 1.8 7.3 7.0 1.3 1 1 0 1 1 1 0 Cytochrome C and Quinol oxidase polypeptide I Dsl1_C PF11989.8 KXS98534.1 - 1.4e-06 28.2 0.0 2.2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal Zw10 PF06248.13 KXS98534.1 - 0.0014 17.3 0.7 0.24 9.9 0.0 2.3 2 0 0 2 2 2 2 Centromere/kinetochore Zw10 Syntaxin-6_N PF09177.11 KXS98534.1 - 0.13 12.9 4.3 0.71 10.5 0.1 3.6 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Cdh1_DBD_1 PF18196.1 KXS98534.1 - 0.32 11.3 4.2 0.64 10.3 0.0 3.0 2 1 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 YlqD PF11068.8 KXS98534.1 - 5.5 7.4 7.9 1.1 9.6 3.2 2.1 2 0 0 2 2 2 0 YlqD protein RhoGEF PF00621.20 KXS98535.1 - 3.6e-32 112.1 0.1 1.9e-31 109.7 0.0 2.1 2 0 0 2 2 2 1 RhoGEF domain BAR PF03114.18 KXS98535.1 - 3e-17 63.1 0.8 6.9e-17 61.9 0.8 1.7 1 0 0 1 1 1 1 BAR domain eIF2A PF08662.11 KXS98536.1 - 2.2e-39 135.4 1.8 2.5e-36 125.4 0.2 3.6 2 2 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Fasciclin PF02469.22 KXS98536.1 - 1e-32 113.1 6.1 9.5e-20 71.1 0.1 3.0 3 0 0 3 3 3 2 Fasciclin domain RRM_1 PF00076.22 KXS98536.1 - 3e-05 23.8 0.0 7.9e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UTP25 PF06862.12 KXS98536.1 - 0.017 13.9 0.0 0.027 13.3 0.0 1.2 1 0 0 1 1 1 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 WD40 PF00400.32 KXS98536.1 - 0.032 15.1 1.3 3.6 8.6 0.0 3.9 4 0 0 4 4 4 0 WD domain, G-beta repeat PALP PF00291.25 KXS98537.1 - 3.9e-59 200.5 0.2 4.4e-59 200.3 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme NRD1_2 PF01995.16 KXS98537.1 - 0.062 12.6 0.1 0.15 11.3 0.0 1.6 2 0 0 2 2 2 0 NrpR regulatory domains NRD1 and 2 4HBT_3 PF13622.6 KXS98539.1 - 7.9e-49 167.1 0.1 9e-49 167.0 0.1 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Phosphodiest PF01663.22 KXS98544.1 - 1.4e-29 103.8 0.0 3.2e-29 102.7 0.0 1.5 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase HD PF01966.22 KXS98544.1 - 6.6e-08 32.8 0.0 1.3e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 HD domain HD_4 PF13328.6 KXS98544.1 - 0.0016 18.2 0.2 0.0031 17.3 0.2 1.4 1 0 0 1 1 1 1 HD domain MIOX PF05153.15 KXS98544.1 - 0.036 13.7 0.0 0.057 13.0 0.0 1.2 1 0 0 1 1 1 0 Myo-inositol oxygenase HDOD PF08668.12 KXS98544.1 - 0.13 11.8 0.0 0.33 10.4 0.1 1.6 2 0 0 2 2 2 0 HDOD domain FAA_hydrolase PF01557.18 KXS98545.1 - 2.3e-49 168.0 0.0 3.7e-49 167.3 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Pro-kuma_activ PF09286.11 KXS98545.1 - 1.4e-40 138.8 0.6 8e-40 136.4 0.1 2.2 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KXS98545.1 - 7.5e-05 22.1 0.2 0.00014 21.3 0.2 1.3 1 0 0 1 1 1 1 Subtilase family Chitin_synth_1 PF01644.17 KXS98546.1 - 2.2e-77 258.6 0.0 3.2e-77 258.1 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KXS98546.1 - 1.5e-27 95.3 0.1 3.1e-27 94.3 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KXS98546.1 - 7.7e-23 80.9 1.0 1.4e-21 76.7 0.0 2.3 2 0 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.6 KXS98546.1 - 1.2e-06 28.6 0.4 1.2e-06 28.6 0.4 2.3 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KXS98546.1 - 0.022 14.7 0.0 0.089 12.7 0.0 1.8 1 1 0 2 2 2 0 Glycosyltransferase like family 2 YesK PF14150.6 KXS98546.1 - 0.47 10.7 7.5 0.32 11.2 3.9 2.5 1 1 1 2 2 2 0 YesK-like protein DUF3989 PF13150.6 KXS98546.1 - 3.4 7.5 5.7 12 5.7 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) PHD PF00628.29 KXS98547.1 - 1.2e-08 34.7 8.8 2.8e-08 33.5 8.8 1.7 1 0 0 1 1 1 1 PHD-finger SET PF00856.28 KXS98547.1 - 2.8e-06 27.8 0.2 3.7e-05 24.2 0.0 2.7 2 1 0 2 2 2 1 SET domain DnaJ_C PF01556.18 KXS98548.1 - 1.5e-37 129.0 0.0 2.1e-37 128.5 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KXS98548.1 - 6.2e-23 80.7 2.2 1.4e-22 79.6 2.2 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KXS98548.1 - 2.7e-09 37.2 22.2 5.9e-09 36.2 22.2 1.6 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KXS98548.1 - 0.13 12.3 13.2 1.9 8.5 3.1 2.7 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KXS98548.1 - 5 7.2 9.5 49 4.0 1.2 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc-ribbons_6 PF07191.12 KXS98548.1 - 6.2 6.9 6.7 15 5.7 6.7 1.6 1 1 0 1 1 1 0 zinc-ribbons FPV060 PF17614.2 KXS98549.1 - 0.011 15.2 1.5 0.072 12.5 0.1 2.1 2 0 0 2 2 2 0 Viral CC-type chemokine DUF1746 PF08508.10 KXS98550.1 - 9.4e-40 135.5 0.5 1.4e-39 135.0 0.5 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) Peptidase_A4 PF01828.17 KXS98551.1 - 1.7e-53 181.2 2.5 2.3e-53 180.8 2.5 1.1 1 0 0 1 1 1 1 Peptidase A4 family Peptidase_A4 PF01828.17 KXS98552.1 - 1.9e-53 181.0 2.5 2.5e-53 180.7 2.5 1.1 1 0 0 1 1 1 1 Peptidase A4 family AA_permease_2 PF13520.6 KXS98553.1 - 7.6e-52 176.6 52.1 9.8e-52 176.2 52.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXS98553.1 - 3.8e-24 85.1 46.6 5.1e-24 84.7 46.6 1.0 1 0 0 1 1 1 1 Amino acid permease YlaH PF14036.6 KXS98553.1 - 0.28 11.6 8.9 0.063 13.6 1.4 3.2 3 0 0 3 3 3 0 YlaH-like protein DUF1077 PF06417.12 KXS98554.1 - 3.2e-48 162.6 0.9 4e-48 162.3 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) VMA21 PF09446.10 KXS98555.1 - 1.5e-16 60.3 8.2 2.1e-16 59.8 8.2 1.2 1 0 0 1 1 1 1 VMA21-like domain MTP18 PF10558.9 KXS98557.1 - 1e-82 276.2 0.3 1.3e-82 275.9 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) Peptidase_M35 PF02102.15 KXS98558.1 - 4.7e-112 374.4 20.5 5.6e-112 374.2 20.5 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 KXS98558.1 - 9.9e-43 146.2 5.6 2e-42 145.1 5.6 1.5 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 KXS98558.1 - 1.4e-05 24.8 4.4 3.6e-05 23.4 4.4 1.6 1 1 0 1 1 1 1 Putative peptidase family CEP170_C PF15308.6 KXS98558.1 - 5.6 5.4 11.8 8.1 4.9 11.8 1.1 1 0 0 1 1 1 0 CEP170 C-terminus Peptidase_M35 PF02102.15 KXS98559.1 - 3.6e-114 381.4 19.0 4e-114 381.2 19.0 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 KXS98559.1 - 1e-42 146.1 5.6 2.1e-42 145.1 5.6 1.5 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 KXS98559.1 - 2.2e-05 24.1 2.9 5.8e-05 22.8 2.9 1.6 1 1 0 1 1 1 1 Putative peptidase family CEP170_C PF15308.6 KXS98559.1 - 5.7 5.4 11.8 8.3 4.8 11.8 1.1 1 0 0 1 1 1 0 CEP170 C-terminus COesterase PF00135.28 KXS98560.1 - 1.5e-86 291.3 0.0 1.9e-86 291.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXS98560.1 - 0.0002 21.3 0.0 0.00087 19.2 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Glyco_hydro_31 PF01055.26 KXS98561.1 - 6.5e-56 190.4 6.3 8.8e-56 189.9 6.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Cyclophil_like PF04126.13 KXS98561.1 - 0.029 14.2 0.2 0.082 12.7 0.1 1.8 2 0 0 2 2 2 0 Cyclophilin-like Myosin_head PF00063.21 KXS98563.1 - 1.8e-242 806.4 7.4 2.2e-242 806.1 7.4 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 KXS98563.1 - 1.3e-52 178.3 0.0 2.4e-52 177.3 0.0 1.5 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 KXS98563.1 - 1.9e-13 49.7 0.2 3.7e-13 48.8 0.2 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXS98563.1 - 3.2e-13 49.3 0.1 7.4e-13 48.1 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KXS98563.1 - 6.5e-09 35.4 0.0 1.3e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain AAA_16 PF13191.6 KXS98563.1 - 0.019 15.4 0.0 0.074 13.4 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain IQ PF00612.27 KXS98563.1 - 0.034 13.9 9.4 1.1 9.2 1.6 2.7 1 1 1 2 2 2 0 IQ calmodulin-binding motif AAA_22 PF13401.6 KXS98563.1 - 0.055 13.7 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KXS98563.1 - 0.12 12.0 0.1 0.33 10.7 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.12 KXS98563.1 - 0.13 12.2 0.0 0.35 10.8 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Hpr_kinase_C PF07475.12 KXS98563.1 - 0.32 10.5 3.2 7.9 6.0 0.0 2.7 3 0 0 3 3 3 0 HPr Serine kinase C-terminal domain YjeF_N PF03853.15 KXS98564.1 - 2.8e-20 72.9 0.0 4e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus DprA_WH PF17782.1 KXS98564.1 - 0.023 14.8 0.4 0.041 14.0 0.4 1.5 1 0 0 1 1 1 0 DprA winged helix domain YjeF_N PF03853.15 KXS98565.1 - 4.7e-34 117.7 0.0 6e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus DprA_WH PF17782.1 KXS98565.1 - 0.024 14.7 0.3 0.057 13.5 0.3 1.7 1 0 0 1 1 1 0 DprA winged helix domain Phage_T7_Capsid PF05396.11 KXS98565.1 - 0.24 11.8 0.5 0.62 10.4 0.0 1.8 2 0 0 2 2 2 0 Phage T7 capsid assembly protein Zn_clus PF00172.18 KXS98566.1 - 4.3e-05 23.6 11.5 8.9e-05 22.5 11.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXS98566.1 - 0.0089 14.9 0.3 0.016 14.0 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS98567.1 - 4.3e-05 23.6 11.5 8.9e-05 22.5 11.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXS98567.1 - 0.0089 14.9 0.3 0.016 14.0 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain COesterase PF00135.28 KXS98568.1 - 1.7e-75 254.8 0.6 2.3e-75 254.5 0.6 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXS98568.1 - 1.4e-06 28.4 0.2 1e-05 25.5 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXS98569.1 - 1.4e-75 255.1 0.6 1.8e-75 254.8 0.6 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXS98569.1 - 1.2e-06 28.5 0.2 9.9e-06 25.6 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXS98570.1 - 1.7e-75 254.8 0.6 2.3e-75 254.5 0.6 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXS98570.1 - 1.4e-06 28.4 0.2 1e-05 25.5 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Zn_clus PF00172.18 KXS98571.1 - 4.3e-05 23.6 11.5 8.9e-05 22.5 11.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXS98571.1 - 0.0089 14.9 0.3 0.016 14.0 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Rep_fac_C PF08542.11 KXS98572.1 - 1.1e-16 61.0 0.0 2e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 KXS98572.1 - 8.6e-15 55.3 0.0 2.9e-14 53.6 0.0 1.9 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KXS98572.1 - 6.2e-12 45.6 0.0 1.8e-07 31.1 0.0 2.7 3 0 0 3 3 3 2 DNA polymerase III, delta subunit Rad17 PF03215.15 KXS98572.1 - 1.8e-08 34.5 0.0 3.9e-08 33.4 0.0 1.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_22 PF13401.6 KXS98572.1 - 4e-06 27.1 0.0 1.3e-05 25.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXS98572.1 - 1.5e-05 25.4 0.2 0.00051 20.5 0.0 2.7 2 2 1 3 3 2 1 AAA ATPase domain RuvB_N PF05496.12 KXS98572.1 - 4e-05 23.4 0.0 0.00011 22.0 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 KXS98572.1 - 4.6e-05 23.3 0.0 9.6e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 KXS98572.1 - 0.00023 21.5 0.1 0.00071 19.9 0.1 1.9 1 0 0 1 1 1 1 AAA C-terminal domain Mg_chelatase PF01078.21 KXS98572.1 - 0.00048 19.6 0.0 0.026 13.9 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KXS98572.1 - 0.0018 18.0 0.0 0.005 16.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KXS98572.1 - 0.0031 17.5 0.1 0.027 14.5 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 KXS98572.1 - 0.0039 16.4 0.0 0.0061 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 KXS98572.1 - 0.0067 16.5 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KXS98572.1 - 0.0097 16.2 0.0 0.021 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXS98572.1 - 0.014 15.7 0.0 0.097 13.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KXS98572.1 - 0.014 14.9 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TPM_phosphatase PF04536.14 KXS98572.1 - 0.019 15.2 0.0 1.6 8.9 0.0 2.7 3 0 0 3 3 2 0 TPM domain AAA_30 PF13604.6 KXS98572.1 - 0.031 14.0 0.2 0.21 11.3 0.0 2.6 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KXS98572.1 - 0.033 13.4 0.0 0.064 12.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DNA_pol3_delta PF06144.13 KXS98572.1 - 0.038 13.8 0.0 0.069 12.9 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit ResIII PF04851.15 KXS98572.1 - 0.047 13.7 0.0 0.14 12.1 0.0 1.7 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_3 PF07726.11 KXS98572.1 - 0.052 13.4 0.0 0.58 10.0 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KXS98572.1 - 0.058 13.9 0.0 0.18 12.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KXS98572.1 - 0.088 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DEAD PF00270.29 KXS98572.1 - 0.11 12.2 0.1 1.1 9.0 0.0 2.1 1 1 0 2 2 2 0 DEAD/DEAH box helicase RNA_helicase PF00910.22 KXS98572.1 - 0.15 12.4 0.0 0.34 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Ribosomal_60s PF00428.19 KXS98572.1 - 0.18 12.4 2.2 7 7.3 0.0 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein SKG6 PF08693.10 KXS98573.1 - 1.2e-07 31.1 0.0 1.2e-07 31.1 0.0 2.3 2 0 0 2 2 2 1 Transmembrane alpha-helix domain TMEM154 PF15102.6 KXS98573.1 - 0.022 14.6 0.0 0.022 14.6 0.0 2.3 1 1 1 2 2 2 0 TMEM154 protein family YajC PF02699.15 KXS98573.1 - 0.069 13.0 0.2 0.16 11.9 0.0 1.6 2 0 0 2 2 2 0 Preprotein translocase subunit Presenilin PF01080.17 KXS98573.1 - 0.38 9.5 1.1 0.64 8.7 1.1 1.2 1 0 0 1 1 1 0 Presenilin Dicty_REP PF05086.12 KXS98573.1 - 0.43 8.5 0.4 0.47 8.4 0.4 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Macoilin PF09726.9 KXS98573.1 - 0.54 8.7 3.1 0.6 8.6 3.1 1.1 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 KXS98573.1 - 0.94 8.2 5.3 1.2 7.9 5.3 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF515 PF04415.12 KXS98573.1 - 4 5.7 16.6 6.1 5.1 16.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) ATP19 PF11022.8 KXS98574.1 - 3.6e-30 104.1 0.3 4e-30 104.0 0.3 1.0 1 0 0 1 1 1 1 ATP synthase subunit K Halogen_Hydrol PF10112.9 KXS98574.1 - 0.099 12.7 0.0 0.11 12.5 0.0 1.0 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein AAA_33 PF13671.6 KXS98575.1 - 7.6e-20 71.5 0.0 9.4e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXS98575.1 - 1.8e-10 41.4 0.0 2.6e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KXS98575.1 - 1.2e-09 37.8 0.0 1.5e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin KTI12 PF08433.10 KXS98575.1 - 3.1e-06 26.9 0.0 4.2e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.6 KXS98575.1 - 9.1e-05 22.9 0.0 0.0003 21.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain dNK PF01712.19 KXS98575.1 - 0.00046 20.1 0.1 0.77 9.6 0.0 2.2 1 1 1 2 2 2 2 Deoxynucleoside kinase NB-ARC PF00931.22 KXS98575.1 - 0.0035 16.6 0.0 0.0052 16.0 0.0 1.4 1 1 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 KXS98575.1 - 0.0094 16.2 0.0 0.03 14.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.20 KXS98575.1 - 0.012 15.5 0.1 0.17 11.7 0.1 2.2 1 1 0 1 1 1 0 Adenylylsulphate kinase AAA_16 PF13191.6 KXS98575.1 - 0.014 15.7 0.0 0.022 15.1 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Viral_helicase1 PF01443.18 KXS98575.1 - 0.032 14.0 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 KXS98575.1 - 0.036 14.1 0.0 0.061 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KXS98575.1 - 0.13 12.6 0.0 0.38 11.2 0.0 1.8 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 KXS98575.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain TniB PF05621.11 KXS98575.1 - 0.15 11.4 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Abhydrolase_6 PF12697.7 KXS98577.1 - 3.7e-22 80.0 0.1 3.7e-22 80.0 0.1 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXS98577.1 - 3.3e-07 30.2 0.1 2.3e-06 27.4 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXS98577.1 - 7.3e-06 25.4 0.0 1.2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KXS98577.1 - 0.001 19.2 1.0 0.023 14.8 0.9 2.4 1 1 0 1 1 1 1 Thioesterase domain Lipase_3 PF01764.25 KXS98577.1 - 0.056 13.3 0.1 0.1 12.5 0.1 1.4 1 0 0 1 1 1 0 Lipase (class 3) GalP_UDP_transf PF01087.22 KXS98578.1 - 9.7e-71 238.0 0.2 6.6e-70 235.3 0.2 2.0 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 KXS98578.1 - 2.7e-59 199.6 0.0 5.7e-59 198.6 0.0 1.5 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain Methyltransf_28 PF02636.17 KXS98578.1 - 0.071 12.7 0.0 0.3 10.7 0.0 1.9 2 1 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase CBS PF00571.28 KXS98581.1 - 6.9e-09 36.0 0.0 0.0053 17.2 0.0 3.1 2 1 0 2 2 2 2 CBS domain Amidase PF01425.21 KXS98583.1 - 1.7e-79 267.9 0.8 9.6e-77 258.8 0.2 2.0 2 0 0 2 2 2 2 Amidase DUF2406 PF10295.9 KXS98584.1 - 1.9e-23 82.9 0.3 8e-23 80.9 0.1 2.2 2 0 0 2 2 2 1 Uncharacterised protein (DUF2406) DUF1102 PF06510.11 KXS98584.1 - 1.8 8.8 3.7 0.84 9.8 0.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1102) LMBR1 PF04791.16 KXS98585.1 - 7.8e-22 77.9 21.5 2.6e-21 76.1 1.2 2.5 2 1 1 3 3 3 2 LMBR1-like membrane protein PorA PF11271.8 KXS98585.1 - 0.015 14.6 0.1 0.036 13.4 0.0 1.6 2 0 0 2 2 2 0 Porin PorA GWT1 PF06423.12 KXS98585.1 - 8 6.6 24.3 2.1 8.4 1.9 4.3 2 2 1 3 3 3 0 GWT1 Mito_carr PF00153.27 KXS98587.1 - 1.7e-47 159.3 6.3 2.8e-17 62.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PhyH PF05721.13 KXS98589.1 - 1.3e-23 84.4 0.0 1.7e-23 84.0 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 KXS98589.1 - 0.00069 20.0 0.0 0.0013 19.1 0.0 1.5 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.6 KXS98589.1 - 0.087 13.7 0.0 0.18 12.7 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily MutS_V PF00488.21 KXS98591.1 - 1.9e-72 243.2 0.0 3.4e-72 242.4 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KXS98591.1 - 8.9e-41 140.2 8.0 1.9e-40 139.1 8.0 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KXS98591.1 - 1.2e-20 73.8 0.1 3.8e-20 72.2 0.1 1.8 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 KXS98591.1 - 1.7e-07 31.6 0.0 4.9e-07 30.1 0.0 1.8 1 0 0 1 1 1 1 MutS domain II AAA_14 PF13173.6 KXS98591.1 - 0.0019 18.2 0.0 0.24 11.4 0.0 3.0 3 0 0 3 3 3 1 AAA domain SnoaL_3 PF13474.6 KXS98591.1 - 0.005 17.1 0.0 0.014 15.7 0.0 1.7 1 0 0 1 1 1 1 SnoaL-like domain T2SSE PF00437.20 KXS98591.1 - 0.0054 15.8 0.3 3.2 6.7 0.1 3.1 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_29 PF13555.6 KXS98591.1 - 0.063 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KXS98591.1 - 0.083 13.4 4.5 0.2 12.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF4089 PF13318.6 KXS98591.1 - 0.21 12.1 1.4 60 4.2 0.2 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4089) HTH_37 PF13744.6 KXS98591.1 - 0.87 9.6 4.0 7.7 6.6 0.4 3.9 4 0 0 4 4 4 0 Helix-turn-helix domain PWI PF01480.17 KXS98592.1 - 8e-25 87.0 0.1 1.3e-24 86.3 0.1 1.3 1 0 0 1 1 1 1 PWI domain Peptidase_M20 PF01546.28 KXS98593.1 - 6.1e-35 120.8 0.0 1.2e-34 119.8 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KXS98593.1 - 8e-15 54.7 0.1 1.6e-14 53.7 0.1 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KXS98593.1 - 0.0029 17.3 0.0 0.0069 16.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 adh_short_C2 PF13561.6 KXS98595.1 - 6.3e-53 179.7 1.6 2.9e-28 99.0 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS98595.1 - 6.1e-43 146.6 0.9 1.7e-27 96.2 0.2 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 KXS98595.1 - 1e-11 45.1 0.2 2e-11 44.1 0.2 1.5 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXS98595.1 - 0.011 14.8 0.1 0.021 13.9 0.1 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 KXS98595.1 - 0.048 13.1 0.9 0.054 12.9 0.1 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 120_Rick_ant PF12574.8 KXS98595.1 - 0.18 11.0 0.0 0.29 10.3 0.0 1.3 1 0 0 1 1 1 0 120 KDa Rickettsia surface antigen ETC_C1_NDUFA5 PF04716.14 KXS98596.1 - 1.8e-23 82.1 1.2 9.7e-22 76.6 0.2 2.3 2 0 0 2 2 2 2 ETC complex I subunit conserved region BRO1 PF03097.18 KXS98597.1 - 9.3e-135 449.4 4.1 9.3e-135 449.4 4.1 2.6 2 1 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KXS98597.1 - 7.6e-81 271.6 19.3 7.6e-81 271.6 19.3 2.0 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV GCP_N_terminal PF17681.1 KXS98597.1 - 0.0042 16.8 1.5 0.01 15.5 1.5 1.6 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal DSBA PF01323.20 KXS98597.1 - 0.092 12.5 1.7 0.31 10.8 1.7 1.9 1 0 0 1 1 1 0 DSBA-like thioredoxin domain Uteroglobin PF01099.17 KXS98597.1 - 0.33 11.3 1.4 23 5.4 0.0 3.9 4 0 0 4 4 4 0 Uteroglobin family Syntaxin-6_N PF09177.11 KXS98597.1 - 4.6 7.9 14.2 1.2 9.7 1.4 4.5 2 2 2 4 4 4 0 Syntaxin 6, N-terminal Glyco_hydro_17 PF00332.18 KXS98598.1 - 0.046 13.3 0.2 0.1 12.2 0.2 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 E1-E2_ATPase PF00122.20 KXS98599.1 - 1.7e-37 128.7 9.1 2.5e-36 124.9 0.6 4.2 4 1 0 4 4 4 2 E1-E2 ATPase Hydrolase PF00702.26 KXS98599.1 - 8.5e-16 58.9 0.0 2.4e-15 57.4 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXS98599.1 - 4.3e-10 39.1 0.0 9.3e-10 38.1 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KXS98599.1 - 0.001 19.1 0.0 0.0029 17.6 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KXS98599.1 - 0.016 14.9 0.0 0.041 13.6 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase SNF2_N PF00176.23 KXS98600.1 - 3.8e-52 177.2 0.0 7.1e-52 176.3 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXS98600.1 - 6.6e-16 58.6 0.0 2.4e-15 56.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXS98600.1 - 4.4e-09 36.6 0.0 1.2e-08 35.2 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KXS98600.1 - 3e-05 23.4 1.0 9.3e-05 21.7 1.0 1.8 1 1 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase CUE PF02845.16 KXS98600.1 - 4.3e-05 23.1 0.0 0.00011 21.9 0.0 1.7 1 0 0 1 1 1 1 CUE domain HIGH_NTase1_ass PF16581.5 KXS98600.1 - 0.0015 18.6 0.2 0.0036 17.3 0.2 1.6 1 0 0 1 1 1 1 Cytidyltransferase-related C-terminal region Zip PF02535.22 KXS98601.1 - 1.8e-48 165.5 6.1 1.3e-47 162.7 6.1 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter Glyco_hydro_43 PF04616.14 KXS98601.1 - 3.1e-13 49.7 0.6 6.3e-13 48.7 0.6 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Asp PF00026.23 KXS98601.1 - 4.5e-07 29.6 0.0 7.4e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease DUF4690 PF15756.5 KXS98601.1 - 0.013 16.1 0.2 0.075 13.6 0.2 2.3 1 0 0 1 1 1 0 Small Novel Rich in Cartilage CYYR1 PF10873.8 KXS98601.1 - 0.023 15.2 0.0 0.08 13.4 0.0 1.9 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 VSP PF03302.13 KXS98601.1 - 0.04 12.8 0.4 0.067 12.0 0.4 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein EphA2_TM PF14575.6 KXS98601.1 - 0.046 14.6 0.1 0.19 12.6 0.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF202 PF02656.15 KXS98601.1 - 0.15 12.6 0.3 1.6 9.2 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF202) MHYT PF03707.16 KXS98601.1 - 1.4 9.2 7.7 6.3 7.0 0.4 3.9 3 0 0 3 3 3 0 Bacterial signalling protein N terminal repeat Aa_trans PF01490.18 KXS98602.1 - 1.5e-35 122.7 32.0 1.8e-35 122.5 32.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3602 PF12223.8 KXS98602.1 - 3.4e-14 53.2 16.0 8.8e-14 51.9 7.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) AA_permease_2 PF13520.6 KXS98602.1 - 0.00032 19.7 37.7 0.0085 15.0 37.6 2.2 1 1 0 1 1 1 1 Amino acid permease Adaptin_N PF01602.20 KXS98603.1 - 1.8e-120 403.0 12.9 2.2e-120 402.7 12.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KXS98603.1 - 2.8e-55 186.8 0.3 2.8e-55 186.8 0.3 3.7 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KXS98603.1 - 1e-15 57.9 5.7 2.6e-07 30.9 0.2 4.8 4 1 0 4 4 4 3 HEAT repeats HEAT PF02985.22 KXS98603.1 - 2.6e-10 39.6 2.9 0.02 15.1 0.0 5.8 5 0 0 5 5 5 3 HEAT repeat CLASP_N PF12348.8 KXS98603.1 - 0.00046 19.8 1.3 1 8.8 0.2 3.0 2 1 0 2 2 2 2 CLASP N terminal HEAT_EZ PF13513.6 KXS98603.1 - 0.0032 17.9 2.7 2.8 8.5 0.1 5.0 4 1 1 5 5 5 1 HEAT-like repeat TIP120 PF08623.10 KXS98603.1 - 0.08 12.7 3.4 3.8 7.3 0.1 3.6 3 1 1 4 4 4 0 TATA-binding protein interacting (TIP20) RTP1_C1 PF10363.9 KXS98603.1 - 0.18 12.0 4.9 20 5.4 0.1 3.8 2 1 2 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 KXS98603.1 - 0.56 10.3 5.5 33 4.7 0.0 4.8 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat CPSF_A PF03178.15 KXS98604.1 - 1.7e-71 241.2 0.0 4.3e-71 239.9 0.0 1.7 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.9 KXS98604.1 - 1.6e-24 86.4 0.0 9.6e-24 83.9 0.0 1.9 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Thioredoxin PF00085.20 KXS98605.1 - 3.7e-48 161.8 0.7 5.6e-25 87.3 0.0 4.4 3 1 0 3 3 3 3 Thioredoxin Thioredoxin_6 PF13848.6 KXS98605.1 - 4.5e-15 56.0 0.0 0.00011 22.2 0.0 4.4 3 1 1 4 4 4 4 Thioredoxin-like domain Thioredoxin_2 PF13098.6 KXS98605.1 - 3.8e-08 33.7 3.3 0.045 14.2 0.3 4.3 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KXS98605.1 - 9.8e-08 32.2 0.2 0.19 12.1 0.2 4.4 3 2 1 4 4 4 2 Thioredoxin-like OST3_OST6 PF04756.13 KXS98605.1 - 8.8e-05 22.0 0.0 0.15 11.4 0.1 2.4 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family HyaE PF07449.11 KXS98605.1 - 0.0048 16.8 0.0 3.9 7.5 0.0 3.0 3 0 0 3 3 3 2 Hydrogenase-1 expression protein HyaE TraF PF13728.6 KXS98605.1 - 0.012 15.4 0.1 0.53 10.1 0.0 2.8 3 0 0 3 3 3 0 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 KXS98605.1 - 0.02 14.9 0.0 8.3 6.5 0.0 3.9 5 0 0 5 5 5 0 Thioredoxin domain Thioredoxin_7 PF13899.6 KXS98605.1 - 0.026 14.7 1.7 0.22 11.7 0.2 3.1 3 1 0 3 3 3 0 Thioredoxin-like Thioredoxin_4 PF13462.6 KXS98605.1 - 1.6 8.8 5.4 3.5 7.8 0.4 3.2 4 0 0 4 4 4 0 Thioredoxin DUF697 PF05128.12 KXS98606.1 - 0.076 12.7 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF697) HET PF06985.11 KXS98607.1 - 4e-21 75.9 1.1 5.3e-21 75.5 1.1 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Eryth_link_C PF16915.5 KXS98607.1 - 0.051 13.6 0.1 0.1 12.6 0.0 1.6 1 1 0 1 1 1 0 Annelid erythrocruorin linker subunit C-terminus DUF2415 PF10313.9 KXS98607.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) F-box PF00646.33 KXS98608.1 - 4.1e-09 36.1 0.0 9.5e-09 34.9 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXS98608.1 - 0.00042 20.2 0.0 0.0009 19.1 0.0 1.7 1 0 0 1 1 1 1 F-box-like MFS_1 PF07690.16 KXS98622.1 - 8.4e-14 51.2 39.3 8.4e-14 51.2 39.3 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 KXS98622.1 - 1.1e-06 28.5 5.5 1.1e-06 28.5 5.5 2.6 2 2 0 2 2 2 1 Ion channel regulatory protein UNC-93 TMPIT PF07851.13 KXS98622.1 - 2.3 7.4 6.6 3.4 6.8 1.2 2.2 2 0 0 2 2 2 0 TMPIT-like protein F-box-like PF12937.7 KXS98623.1 - 0.011 15.7 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 KXS98623.1 - 0.022 14.7 0.1 0.04 13.8 0.1 1.4 1 0 0 1 1 1 0 F-box domain peroxidase PF00141.23 KXS98625.1 - 8.6e-24 84.5 0.0 1.8e-23 83.5 0.0 1.4 1 0 0 1 1 1 1 Peroxidase ABC1 PF03109.16 KXS98625.1 - 1.3e-20 73.8 0.0 6.7e-11 42.4 0.0 2.5 2 0 0 2 2 2 2 ABC1 family Intg_mem_TP0381 PF09529.10 KXS98625.1 - 0.12 11.8 0.1 0.19 11.2 0.1 1.2 1 0 0 1 1 1 0 Integral membrane protein (intg_mem_TP0381) LRR_4 PF12799.7 KXS98626.1 - 6.3e-36 121.8 49.7 4.7e-06 26.9 0.9 10.5 5 1 4 11 11 11 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS98626.1 - 1.5e-34 117.6 46.9 1e-07 31.6 6.5 8.5 5 2 4 9 9 9 9 Leucine rich repeat LRR_9 PF14580.6 KXS98626.1 - 4.7e-09 36.0 22.1 0.0025 17.4 1.4 5.6 3 3 2 6 6 6 5 Leucine-rich repeat LRR_1 PF00560.33 KXS98626.1 - 1.1e-06 28.4 43.5 1.1 10.1 0.2 13.9 16 2 1 17 17 17 4 Leucine Rich Repeat LRR_6 PF13516.6 KXS98626.1 - 8.6e-06 25.4 34.5 2.8 8.2 0.2 12.2 13 0 0 13 13 13 3 Leucine Rich repeat Tyrosinase PF00264.20 KXS98627.1 - 3.9e-38 131.9 3.3 7.3e-38 131.1 3.3 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 KXS98627.1 - 2.8e-25 89.4 0.0 5.4e-25 88.4 0.0 1.5 1 0 0 1 1 1 1 Tyosinase C-terminal domain Glyco_hydro_65N PF03636.15 KXS98628.1 - 8.9e-39 133.5 0.0 2.2e-38 132.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65m PF03632.15 KXS98628.1 - 1.6e-27 96.4 0.4 1.1e-26 93.6 0.3 2.0 1 1 1 2 2 2 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65C PF03633.15 KXS98628.1 - 0.00017 21.4 0.1 0.00065 19.6 0.1 2.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain F5_F8_type_C PF00754.25 KXS98628.1 - 0.0012 19.0 0.1 0.0057 16.8 0.1 2.3 2 0 0 2 2 2 1 F5/8 type C domain PSI_PsaH PF03244.14 KXS98628.1 - 0.15 11.6 0.4 0.39 10.2 0.4 1.6 1 0 0 1 1 1 0 Photosystem I reaction centre subunit VI eIF-3c_N PF05470.12 KXS98629.1 - 2.6e-171 571.0 25.2 2.6e-171 571.0 25.2 3.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Ferric_reduct PF01794.19 KXS98629.1 - 1e-17 64.4 11.8 2.9e-17 62.9 11.8 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component PCI PF01399.27 KXS98629.1 - 4.8e-12 46.3 1.7 2.4e-11 44.1 0.0 3.1 3 0 0 3 3 3 1 PCI domain NAD_binding_6 PF08030.12 KXS98629.1 - 3.2e-10 40.3 1.8 7.8e-05 22.9 0.0 2.9 3 0 0 3 3 3 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KXS98629.1 - 1.1e-07 31.8 0.1 1.4e-06 28.4 0.0 2.7 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.21 KXS98629.1 - 0.0015 19.1 0.6 0.017 15.8 0.0 3.1 4 0 0 4 4 4 1 Oxidoreductase NAD-binding domain DUF4381 PF14316.6 KXS98629.1 - 0.05 13.8 0.1 0.23 11.7 0.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) CDC45 PF02724.14 KXS98629.1 - 2 6.6 15.0 3.5 5.8 15.0 1.3 1 0 0 1 1 1 0 CDC45-like protein BSP_II PF05432.11 KXS98629.1 - 2 8.0 19.1 4.5 6.9 19.1 1.5 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) TssN PF17555.2 KXS98629.1 - 2.5 7.4 12.9 0.072 12.5 6.6 1.5 2 0 0 2 2 2 0 Type VI secretion system, TssN YcbB PF08664.10 KXS98630.1 - 0.22 11.6 0.0 0.45 10.6 0.0 1.4 1 0 0 1 1 1 0 YcbB domain NumbF PF06311.12 KXS98630.1 - 3.5 8.2 14.4 0.6 10.7 1.2 3.8 3 1 0 4 4 4 0 NUMB domain F-box PF00646.33 KXS98631.1 - 0.0024 17.7 0.0 0.022 14.6 0.0 2.4 2 0 0 2 2 2 1 F-box domain Sigma70_r4 PF04545.16 KXS98631.1 - 0.28 10.8 2.5 1.2 8.7 0.2 2.8 2 0 0 2 2 2 0 Sigma-70, region 4 DnaJ PF00226.31 KXS98632.1 - 8.7e-21 73.8 0.5 2.1e-20 72.6 0.5 1.7 1 0 0 1 1 1 1 DnaJ domain DnaJ PF00226.31 KXS98633.1 - 8.7e-21 73.8 0.5 2.1e-20 72.6 0.5 1.7 1 0 0 1 1 1 1 DnaJ domain MT0933_antitox PF14013.6 KXS98634.1 - 0.058 13.7 8.3 1.6 9.1 3.6 3.2 2 1 1 3 3 3 0 MT0933-like antitoxin protein UNC-93 PF05978.16 KXS98635.1 - 2.1e-13 50.3 7.6 2.1e-13 50.3 7.6 2.7 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 KXS98635.1 - 3e-07 29.7 37.6 3e-07 29.7 37.6 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Podoplanin PF05808.11 KXS98637.1 - 0.0003 20.9 3.6 0.00055 20.1 3.6 1.4 1 0 0 1 1 1 1 Podoplanin SKG6 PF08693.10 KXS98637.1 - 0.0096 15.3 0.9 0.019 14.4 0.9 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain RCR PF12273.8 KXS98637.1 - 0.039 14.6 0.0 0.11 13.1 0.0 1.8 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Mid2 PF04478.12 KXS98637.1 - 0.072 12.9 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF347 PF03988.12 KXS98637.1 - 0.15 12.2 0.1 0.35 11.1 0.1 1.6 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Ribosomal_L50 PF10501.9 KXS98638.1 - 1.7e-07 31.4 0.3 1.7e-07 31.4 0.3 1.9 2 0 0 2 2 2 1 Ribosomal subunit 39S DUF3734 PF12536.8 KXS98638.1 - 0.83 10.0 3.3 1.1 9.6 0.0 2.6 3 0 0 3 3 3 0 Patatin phospholipase PTR2 PF00854.21 KXS98640.1 - 3.2e-89 299.5 9.5 5.4e-89 298.8 8.3 1.9 1 1 1 2 2 2 1 POT family Aa_trans PF01490.18 KXS98641.1 - 5.2e-38 130.8 33.5 6.3e-38 130.5 33.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Cg6151-P PF10233.9 KXS98641.1 - 0.0066 16.7 1.8 0.0066 16.7 1.8 3.7 5 1 0 5 5 5 1 Uncharacterized conserved protein CG6151-P MFS_1 PF07690.16 KXS98642.1 - 6.8e-22 77.9 40.2 3.2e-12 46.0 10.5 2.9 2 1 1 3 3 3 3 Major Facilitator Superfamily Aldo_ket_red PF00248.21 KXS98643.1 - 8.7e-44 149.9 0.0 1.2e-43 149.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family CBM_14 PF01607.24 KXS98644.1 - 1.3e-06 28.5 9.9 1.8e-06 28.0 8.0 2.1 2 1 0 2 2 2 1 Chitin binding Peritrophin-A domain Hva1_TUDOR PF11160.8 KXS98645.1 - 6.5e-15 55.0 3.6 6.5e-15 55.0 3.6 2.5 2 1 1 3 3 3 1 Hypervirulence associated proteins TUDOR domain CDC45 PF02724.14 KXS98645.1 - 1.3 7.2 27.2 1.7 6.9 27.2 1.2 1 0 0 1 1 1 0 CDC45-like protein LAP1C PF05609.12 KXS98645.1 - 8.7 5.3 22.4 11 5.0 22.4 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) MFS_Mycoplasma PF07672.13 KXS98646.1 - 0.0072 15.6 0.0 0.0097 15.2 0.0 1.2 1 0 0 1 1 1 1 Mycoplasma MFS transporter adh_short_C2 PF13561.6 KXS98647.1 - 4.5e-51 173.7 0.1 5.6e-51 173.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS98647.1 - 7.6e-38 129.9 0.2 1.1e-37 129.4 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS98647.1 - 3.4e-07 30.4 1.1 1e-06 28.8 1.1 1.7 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KXS98648.1 - 4.5e-51 173.7 0.1 5.6e-51 173.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS98648.1 - 7.6e-38 129.9 0.2 1.1e-37 129.4 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS98648.1 - 3.4e-07 30.4 1.1 1e-06 28.8 1.1 1.7 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KXS98649.1 - 4.5e-51 173.7 0.1 5.6e-51 173.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS98649.1 - 7.6e-38 129.9 0.2 1.1e-37 129.4 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS98649.1 - 3.4e-07 30.4 1.1 1e-06 28.8 1.1 1.7 1 1 0 1 1 1 1 KR domain Arrestin_N PF00339.29 KXS98650.1 - 0.00012 22.2 0.0 0.0097 16.0 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain zf_UBZ PF18439.1 KXS98651.1 - 0.18 11.5 1.7 9.7 5.9 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_2 PF13240.6 KXS98651.1 - 1 9.2 5.5 3.3 7.6 0.3 3.1 3 0 0 3 3 3 0 zinc-ribbon domain DUF3632 PF12311.8 KXS98653.1 - 3.9e-10 40.4 2.4 4.8e-10 40.1 2.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) DUF3632 PF12311.8 KXS98654.1 - 3.9e-10 40.4 2.4 4.8e-10 40.1 2.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Alpha_Helical PF18489.1 KXS98655.1 - 0.062 13.5 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Alpha helical domain PTS_IIA PF02255.16 KXS98655.1 - 0.12 12.4 0.1 0.21 11.7 0.1 1.4 1 0 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIA subunit Alpha_Helical PF18489.1 KXS98656.1 - 0.05 13.8 0.0 0.086 13.0 0.0 1.3 1 0 0 1 1 1 0 Alpha helical domain Ish1 PF10281.9 KXS98656.1 - 0.14 12.5 0.0 0.34 11.2 0.0 1.6 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein DUF2795 PF11387.8 KXS98656.1 - 0.18 12.0 1.2 21 5.4 0.0 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF2795) PfkB PF00294.24 KXS98657.1 - 2.8e-11 43.3 0.0 7.1e-11 42.0 0.0 1.5 1 1 0 1 1 1 1 pfkB family carbohydrate kinase MFS_1 PF07690.16 KXS98661.1 - 3.6e-19 68.9 37.6 3.6e-19 68.9 37.6 3.0 1 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS98661.1 - 1.9e-05 23.7 14.5 1.9e-05 23.7 14.5 3.1 2 2 0 2 2 2 1 Sugar (and other) transporter DUF5392 PF17370.2 KXS98661.1 - 0.2 11.7 0.0 0.2 11.7 0.0 2.3 3 0 0 3 3 3 0 Family of unknown function (DUF5392) OATP PF03137.20 KXS98661.1 - 0.28 9.4 7.1 0.49 8.6 1.5 2.2 1 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 KXS98662.1 - 3.6e-19 68.9 37.6 3.6e-19 68.9 37.6 3.0 1 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS98662.1 - 1.9e-05 23.7 14.5 1.9e-05 23.7 14.5 3.1 2 2 0 2 2 2 1 Sugar (and other) transporter DUF5392 PF17370.2 KXS98662.1 - 0.2 11.7 0.0 0.2 11.7 0.0 2.3 3 0 0 3 3 3 0 Family of unknown function (DUF5392) OATP PF03137.20 KXS98662.1 - 0.28 9.4 7.1 0.49 8.6 1.5 2.2 1 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Ribonuclease_3 PF00636.26 KXS98663.1 - 2.2e-11 44.3 0.0 8.2e-11 42.5 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KXS98663.1 - 1.2e-10 41.6 0.0 1.5e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KXS98664.1 - 2.2e-11 44.3 0.0 8.2e-11 42.5 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KXS98664.1 - 1.2e-10 41.6 0.0 1.5e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Hexokinase_2 PF03727.16 KXS98665.1 - 1.1e-56 191.9 0.0 1.5e-56 191.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KXS98665.1 - 7.8e-47 159.7 0.0 1.3e-46 159.0 0.0 1.3 1 0 0 1 1 1 1 Hexokinase NDT80_PhoG PF05224.12 KXS98666.1 - 3e-35 122.1 0.0 6.3e-35 121.1 0.0 1.6 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Glucosamine_iso PF01182.20 KXS98667.1 - 9.8e-20 71.4 0.0 1.7e-19 70.6 0.0 1.4 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase zf-MYND PF01753.18 KXS98668.1 - 3.2e-12 46.3 10.2 3.6e-12 46.2 9.3 1.6 1 1 0 1 1 1 1 MYND finger HypA PF01155.19 KXS98668.1 - 0.005 16.8 2.2 0.011 15.8 2.2 1.6 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA PhnA_Zn_Ribbon PF08274.12 KXS98668.1 - 0.024 14.6 0.2 0.071 13.1 0.2 1.8 1 0 0 1 1 1 0 PhnA Zinc-Ribbon Meleagrin PF08189.11 KXS98668.1 - 0.13 11.9 2.2 0.38 10.5 2.2 1.8 1 0 0 1 1 1 0 Meleagrin/Cygnin family Ecl1 PF12855.7 KXS98668.1 - 0.74 11.0 7.6 0.36 12.0 0.8 2.4 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins zf-C6H2 PF15801.5 KXS98668.1 - 1.2 9.5 12.0 1.6 9.1 9.8 2.4 2 1 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding F-box PF00646.33 KXS98669.1 - 0.079 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 F-box domain Bestrophin PF01062.21 KXS98670.1 - 2.6e-36 125.5 0.1 4.6e-36 124.7 0.1 1.3 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel FMO-like PF00743.19 KXS98671.1 - 9.6e-37 126.6 0.0 5.5e-29 101.0 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXS98671.1 - 2.1e-12 46.9 2.4 8.6e-06 25.2 0.7 3.6 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXS98671.1 - 4.4e-10 39.3 0.0 2e-09 37.1 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXS98671.1 - 4.1e-09 36.5 0.0 1e-08 35.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXS98671.1 - 7.8e-09 35.6 0.8 3.2e-05 23.7 0.1 3.3 2 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXS98671.1 - 2.6e-06 27.5 1.3 0.00044 20.3 0.3 3.7 3 1 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 KXS98671.1 - 2.9e-05 23.4 0.0 6.2e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.24 KXS98671.1 - 3.6e-05 23.2 0.0 0.00058 19.3 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KXS98671.1 - 7.3e-05 23.3 0.0 0.00024 21.6 0.0 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 KXS98671.1 - 0.0006 18.7 0.0 0.001 18.0 0.0 1.3 1 0 0 1 1 1 1 MCRA family HI0933_like PF03486.14 KXS98671.1 - 0.00064 18.5 0.4 0.0012 17.6 0.4 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 KXS98671.1 - 0.0012 18.1 0.4 0.0027 16.9 0.2 1.7 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 KXS98671.1 - 0.0013 18.0 0.0 0.0022 17.3 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 KXS98671.1 - 0.0014 17.9 0.1 0.0026 17.1 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KXS98671.1 - 0.0015 18.0 0.0 0.002 17.6 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase IlvN PF07991.12 KXS98671.1 - 0.0078 15.8 0.0 0.28 10.7 0.0 2.7 3 0 0 3 3 3 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain GIDA PF01134.22 KXS98671.1 - 0.01 15.0 0.4 0.023 13.8 0.4 1.6 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 KXS98671.1 - 0.012 15.4 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KXS98671.1 - 0.028 13.8 0.0 0.087 12.2 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KXS98671.1 - 0.057 13.5 0.0 0.18 11.9 0.0 1.8 2 0 0 2 2 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 KXS98671.1 - 0.077 12.6 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 KXS98671.1 - 0.12 12.8 0.0 0.41 11.1 0.0 2.0 1 1 0 1 1 1 0 Putative NAD(P)-binding FMO-like PF00743.19 KXS98672.1 - 9.6e-37 126.6 0.0 5.5e-29 101.0 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXS98672.1 - 2.1e-12 46.9 2.4 8.6e-06 25.2 0.7 3.6 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXS98672.1 - 4.4e-10 39.3 0.0 2e-09 37.1 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXS98672.1 - 4.1e-09 36.5 0.0 1e-08 35.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXS98672.1 - 7.8e-09 35.6 0.8 3.2e-05 23.7 0.1 3.3 2 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXS98672.1 - 2.6e-06 27.5 1.3 0.00044 20.3 0.3 3.7 3 1 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 KXS98672.1 - 2.9e-05 23.4 0.0 6.2e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.24 KXS98672.1 - 3.6e-05 23.2 0.0 0.00058 19.3 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KXS98672.1 - 7.3e-05 23.3 0.0 0.00024 21.6 0.0 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 KXS98672.1 - 0.0006 18.7 0.0 0.001 18.0 0.0 1.3 1 0 0 1 1 1 1 MCRA family HI0933_like PF03486.14 KXS98672.1 - 0.00064 18.5 0.4 0.0012 17.6 0.4 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 KXS98672.1 - 0.0012 18.1 0.4 0.0027 16.9 0.2 1.7 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 KXS98672.1 - 0.0013 18.0 0.0 0.0022 17.3 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 KXS98672.1 - 0.0014 17.9 0.1 0.0026 17.1 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KXS98672.1 - 0.0015 18.0 0.0 0.002 17.6 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase IlvN PF07991.12 KXS98672.1 - 0.0078 15.8 0.0 0.28 10.7 0.0 2.7 3 0 0 3 3 3 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain GIDA PF01134.22 KXS98672.1 - 0.01 15.0 0.4 0.023 13.8 0.4 1.6 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 KXS98672.1 - 0.012 15.4 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KXS98672.1 - 0.028 13.8 0.0 0.087 12.2 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KXS98672.1 - 0.057 13.5 0.0 0.18 11.9 0.0 1.8 2 0 0 2 2 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 KXS98672.1 - 0.077 12.6 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 KXS98672.1 - 0.12 12.8 0.0 0.41 11.1 0.0 2.0 1 1 0 1 1 1 0 Putative NAD(P)-binding F-box PF00646.33 KXS98673.1 - 5.1e-07 29.4 0.5 1.2e-06 28.3 0.5 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXS98673.1 - 5e-06 26.3 0.1 1.2e-05 25.1 0.1 1.7 1 0 0 1 1 1 1 F-box-like TP6A_N PF04406.14 KXS98678.1 - 1.9e-24 85.4 0.0 6.8e-24 83.6 0.0 2.0 1 0 0 1 1 1 1 Type IIB DNA topoisomerase RIP PF00161.19 KXS98678.1 - 0.12 11.9 0.2 0.25 10.9 0.2 1.5 1 0 0 1 1 1 0 Ribosome inactivating protein AA_permease PF00324.21 KXS98680.1 - 2.7e-13 49.4 2.7 3.1e-13 49.1 2.7 1.0 1 0 0 1 1 1 1 Amino acid permease S_tail_recep_bd PF14928.6 KXS98680.1 - 0.087 13.5 0.0 0.3 11.7 0.0 1.7 1 1 1 2 2 2 0 Short tail fibre protein receptor-binding domain SAP PF02037.27 KXS98681.1 - 0.03 14.1 0.1 0.49 10.2 0.0 2.5 2 0 0 2 2 2 0 SAP domain Bac_rhodopsin PF01036.18 KXS98682.1 - 5.6e-55 186.3 12.2 7.5e-55 185.9 12.2 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein mCpol PF18182.1 KXS98683.1 - 0.18 12.2 2.7 13 6.2 0.0 3.3 3 0 0 3 3 3 0 minimal CRISPR polymerase domain DEAD PF00270.29 KXS98684.1 - 1.2e-41 142.4 0.1 1.9e-41 141.7 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXS98684.1 - 1.5e-32 112.3 0.0 7.9e-32 109.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 KXS98684.1 - 0.00044 20.0 0.0 0.00066 19.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXS98684.1 - 0.00087 19.6 0.0 0.0073 16.7 0.1 2.2 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 KXS98684.1 - 0.0019 18.2 0.0 0.0039 17.2 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 KXS98684.1 - 0.029 14.4 0.1 0.098 12.6 0.0 2.0 2 0 0 2 2 2 0 Flavivirus DEAD domain Helicase_RecD PF05127.14 KXS98684.1 - 0.069 13.0 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Helicase TniB PF05621.11 KXS98684.1 - 0.085 12.3 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein AAA_22 PF13401.6 KXS98684.1 - 0.22 11.8 0.7 0.92 9.8 0.7 2.0 1 1 0 1 1 1 0 AAA domain CAF1A PF12253.8 KXS98685.1 - 1.9e-19 69.6 8.6 1.9e-19 69.6 8.6 3.4 3 1 0 3 3 3 1 Chromatin assembly factor 1 subunit A Borrelia_P83 PF05262.11 KXS98685.1 - 0.017 13.6 24.4 0.031 12.8 24.4 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein SprA-related PF12118.8 KXS98685.1 - 2 7.5 27.4 4.3 6.4 27.4 1.5 1 0 0 1 1 1 0 SprA-related family Red1 PF07964.11 KXS98685.1 - 2.3 6.4 23.2 3.2 5.9 23.2 1.2 1 0 0 1 1 1 0 Rec10 / Red1 Hamartin PF04388.12 KXS98685.1 - 5.1 5.6 22.1 7.3 5.1 22.1 1.2 1 0 0 1 1 1 0 Hamartin protein RAP1 PF07218.11 KXS98685.1 - 8.2 4.6 18.9 13 3.9 18.9 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) AAA_11 PF13086.6 KXS98685.1 - 8.4 6.1 18.1 16 5.2 18.1 1.4 1 0 0 1 1 1 0 AAA domain Raftlin PF15250.6 KXS98685.1 - 9.1 4.9 14.0 19 3.9 14.0 1.6 1 0 0 1 1 1 0 Raftlin DIOX_N PF14226.6 KXS98686.1 - 5.9e-28 98.0 0.0 9.5e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXS98686.1 - 9.9e-18 64.5 0.0 2.1e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_2 PF07719.17 KXS98687.1 - 2.9e-23 80.1 28.0 0.00031 20.6 0.0 11.0 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_1 PF00515.28 KXS98687.1 - 1.2e-22 78.8 15.8 0.0018 18.0 0.0 10.1 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.6 KXS98687.1 - 1.6e-18 65.3 18.0 0.0027 17.8 0.0 10.7 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_19 PF14559.6 KXS98687.1 - 1.5e-17 63.8 20.4 0.024 15.1 0.0 10.7 6 3 3 10 10 10 4 Tetratricopeptide repeat TPR_12 PF13424.6 KXS98687.1 - 1.7e-15 57.1 18.6 0.0015 18.8 1.0 9.1 7 2 1 8 8 8 4 Tetratricopeptide repeat TPR_7 PF13176.6 KXS98687.1 - 2e-12 46.2 11.3 0.07 13.2 0.0 9.5 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.6 KXS98687.1 - 3.7e-11 42.9 20.8 0.022 15.5 0.1 11.5 9 2 2 11 11 10 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXS98687.1 - 7.2e-09 36.2 12.9 0.21 12.2 0.0 7.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 KXS98687.1 - 1.2e-07 31.5 20.3 1.4 9.5 0.2 11.4 13 1 1 14 14 13 1 Tetratricopeptide repeat TPR_6 PF13174.6 KXS98687.1 - 5.8e-07 29.7 25.0 0.0065 17.0 0.1 11.1 12 0 0 12 12 12 1 Tetratricopeptide repeat TPR_10 PF13374.6 KXS98687.1 - 3.3e-06 26.8 14.6 2.2 8.3 0.1 7.2 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 KXS98687.1 - 0.00014 21.5 19.3 1.7 8.4 0.0 8.8 8 1 1 9 9 9 2 TPR repeat Fis1_TPR_C PF14853.6 KXS98687.1 - 0.0075 16.3 0.6 12 6.0 0.0 4.8 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat DUF108 PF01958.18 KXS98687.1 - 0.1 13.0 0.4 0.42 11.0 0.4 2.1 1 1 0 1 1 1 0 Domain of unknown function DUF108 Peptidase_S10 PF00450.22 KXS98688.1 - 2.3e-75 254.6 0.0 3.8e-75 253.9 0.0 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase Peptidase_S9 PF00326.21 KXS98688.1 - 0.022 14.3 0.0 0.3 10.5 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family TRI12 PF06609.13 KXS98689.1 - 4e-33 114.7 18.3 5.5e-33 114.2 18.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KXS98689.1 - 5.7e-20 71.5 43.8 9.7e-20 70.8 40.3 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS98689.1 - 4.7e-08 32.3 7.3 4.7e-08 32.3 7.3 3.1 2 1 1 3 3 3 2 Sugar (and other) transporter Ribosomal_L4 PF00573.22 KXS98690.1 - 8.8e-38 129.9 0.3 1.2e-37 129.5 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 KXS98690.1 - 2.9e-26 91.3 0.3 2.9e-26 91.3 0.3 2.0 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Transp_cyt_pur PF02133.15 KXS98691.1 - 9.3e-19 67.5 40.8 1.7e-18 66.6 40.8 1.4 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Sec8_exocyst PF04048.14 KXS98692.1 - 3.9e-44 150.0 4.6 5.6e-44 149.5 2.2 2.5 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 KXS98692.1 - 9.1e-09 35.0 1.4 2.2e-08 33.7 1.4 1.6 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Zw10 PF06248.13 KXS98692.1 - 0.00017 20.3 0.6 0.00017 20.3 0.6 1.7 2 0 0 2 2 2 1 Centromere/kinetochore Zw10 Vta1_C PF18097.1 KXS98692.1 - 0.053 13.2 0.1 8.8 6.1 0.0 3.6 3 0 0 3 3 3 0 Vta1 C-terminal domain COG2 PF06148.11 KXS98692.1 - 2.5 8.2 4.8 0.68 10.0 0.2 2.5 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 SKG6 PF08693.10 KXS98695.1 - 0.012 15.0 1.3 0.02 14.3 1.3 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SKG6 PF08693.10 KXS98696.1 - 0.01 15.2 1.2 0.017 14.6 1.2 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain WAP PF00095.21 KXS98696.1 - 0.02 15.3 1.0 0.02 15.3 1.0 2.5 2 0 0 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' FAD_binding_8 PF08022.12 KXS98697.1 - 5.5e-21 74.7 0.0 1.1e-20 73.7 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KXS98697.1 - 1.9e-15 57.3 0.0 6.4e-15 55.6 0.0 1.9 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KXS98697.1 - 1.6e-08 34.7 8.1 1.6e-08 34.7 8.1 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component EF-hand_7 PF13499.6 KXS98697.1 - 3.8e-05 24.0 0.5 0.0001 22.7 0.5 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KXS98697.1 - 5.7e-05 22.4 1.2 0.00012 21.4 1.2 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXS98697.1 - 6.4e-05 22.6 1.3 0.00019 21.1 1.3 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 KXS98697.1 - 0.00021 20.6 3.1 0.00021 20.6 3.1 1.8 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 KXS98697.1 - 0.00032 20.5 0.5 0.00087 19.1 0.3 1.8 2 0 0 2 2 2 1 EF-hand domain pair Amidohydro_2 PF04909.14 KXS98698.1 - 1.3e-39 136.7 0.0 2.1e-39 136.1 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase DUF3449 PF11931.8 KXS98699.1 - 2.2e-73 246.0 0.3 2.2e-73 246.0 0.3 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 KXS98699.1 - 1.4e-25 89.6 1.0 4.2e-25 88.1 0.2 2.1 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 KXS98699.1 - 1.9e-12 46.8 0.5 4.2e-12 45.7 0.5 1.6 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.7 KXS98699.1 - 1.8e-08 34.5 2.4 8e-07 29.2 1.0 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KXS98699.1 - 2e-08 34.3 5.0 1.8e-07 31.3 2.2 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KXS98699.1 - 0.00026 21.2 0.6 0.0054 17.0 0.2 2.5 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C4H2 PF10146.9 KXS98699.1 - 0.031 14.6 0.1 0.031 14.6 0.1 2.1 2 0 0 2 2 2 0 Zinc finger-containing protein zf-LYAR PF08790.11 KXS98699.1 - 0.057 13.3 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger zf-C2H2_4 PF13894.6 KXS98699.1 - 0.087 13.7 0.7 28 5.9 0.0 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KXS98699.1 - 2 9.0 3.7 6.8 7.4 0.3 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type SbcD_C PF12320.8 KXS98699.1 - 3.8 7.9 7.6 0.55 10.6 1.5 2.6 2 0 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain zf-DBF PF07535.12 KXS98699.1 - 6.3 7.0 6.8 0.83 9.8 0.8 2.4 2 1 0 2 2 2 0 DBF zinc finger HET PF06985.11 KXS98700.1 - 8.9e-18 65.0 0.5 2e-17 63.9 0.5 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF2125 PF09898.9 KXS98701.1 - 0.037 13.7 0.2 0.038 13.6 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2125) Oxidored_FMN PF00724.20 KXS98703.1 - 4.2e-92 309.0 0.0 4.9e-92 308.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Hydrophobin_2 PF06766.11 KXS98704.1 - 3.7e-19 68.4 6.7 5.1e-19 68.0 6.7 1.2 1 0 0 1 1 1 1 Fungal hydrophobin HsbA PF12296.8 KXS98705.1 - 8.6e-20 71.4 11.3 8.6e-20 71.4 11.3 2.9 2 1 1 3 3 3 1 Hydrophobic surface binding protein A Med3 PF11593.8 KXS98705.1 - 0.0011 18.2 15.2 0.0011 18.2 15.2 1.3 1 1 0 1 1 1 1 Mediator complex subunit 3 fungal MAP65_ASE1 PF03999.12 KXS98705.1 - 0.9 8.2 4.5 1.5 7.4 4.5 1.4 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) CAP PF00188.26 KXS98711.1 - 1.2e-16 61.7 1.1 1.9e-16 61.0 1.1 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Mucin PF01456.17 KXS98711.1 - 1 9.3 17.4 1.9 8.5 17.4 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein SOG2 PF10428.9 KXS98711.1 - 2.4 7.3 5.5 2.9 7.0 5.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Hamartin PF04388.12 KXS98711.1 - 7 5.2 6.6 8.2 4.9 6.6 1.1 1 0 0 1 1 1 0 Hamartin protein Putative_PNPOx PF01243.20 KXS98712.1 - 8.9e-08 32.2 0.0 1.3e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF3658 PF12395.8 KXS98712.1 - 0.05 13.5 0.0 0.091 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function AA_permease_2 PF13520.6 KXS98714.1 - 4.5e-53 180.6 50.6 5.3e-53 180.4 50.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXS98714.1 - 1.6e-24 86.3 40.6 2.2e-24 85.9 40.6 1.1 1 0 0 1 1 1 1 Amino acid permease Aconitase PF00330.20 KXS98715.1 - 1.3e-109 367.2 0.1 9.3e-109 364.5 0.1 2.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KXS98715.1 - 7.8e-23 81.2 0.0 1.9e-22 80.0 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain Peptidase_S64 PF08192.11 KXS98716.1 - 1.4 7.4 11.9 2.1 6.7 11.9 1.2 1 0 0 1 1 1 0 Peptidase family S64 B-block_TFIIIC PF04182.12 KXS98717.1 - 5.8e-15 55.2 0.0 1.6e-14 53.8 0.0 1.8 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC Aldo_ket_red PF00248.21 KXS98718.1 - 3.4e-62 210.3 0.0 5e-62 209.7 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family SBD_N PF07005.11 KXS98718.1 - 5.1e-61 206.3 0.2 8.3e-61 205.6 0.2 1.3 1 0 0 1 1 1 1 Sugar-binding N-terminal domain NBD_C PF17042.5 KXS98718.1 - 1.8e-38 132.7 0.0 5.7e-38 131.1 0.0 1.9 1 0 0 1 1 1 1 Nucleotide-binding C-terminal domain MFS_1 PF07690.16 KXS98720.1 - 1.8e-19 69.9 61.0 2.6e-19 69.4 55.2 2.9 1 1 0 2 2 2 1 Major Facilitator Superfamily UPF0060 PF02694.15 KXS98720.1 - 0.098 12.9 0.4 0.098 12.9 0.4 3.5 5 0 0 5 5 5 0 Uncharacterised BCR, YnfA/UPF0060 family VEGFR-2_TMD PF17988.1 KXS98720.1 - 1.4 8.4 5.8 5.9 6.4 5.8 2.1 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain YabA PF06156.13 KXS98721.1 - 0.0027 18.3 0.4 0.0046 17.6 0.4 1.4 1 1 0 1 1 1 1 Initiation control protein YabA TelA PF05816.11 KXS98721.1 - 0.0043 16.2 1.6 0.0053 15.9 1.6 1.1 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) Cnn_1N PF07989.11 KXS98721.1 - 0.0065 16.6 0.4 0.091 12.9 0.0 2.2 1 1 1 2 2 2 1 Centrosomin N-terminal motif 1 DUF4201 PF13870.6 KXS98721.1 - 0.0082 15.9 0.3 0.01 15.6 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) TMF_DNA_bd PF12329.8 KXS98721.1 - 0.0089 16.0 1.7 0.0089 16.0 1.7 1.5 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding EzrA PF06160.12 KXS98721.1 - 0.014 13.6 0.6 0.016 13.4 0.6 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF3450 PF11932.8 KXS98721.1 - 0.016 14.5 4.9 0.02 14.2 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Fmp27_WPPW PF10359.9 KXS98721.1 - 0.017 14.0 0.3 0.02 13.8 0.3 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Ax_dynein_light PF10211.9 KXS98721.1 - 0.021 14.8 0.9 0.028 14.4 0.9 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain V_ATPase_I PF01496.19 KXS98721.1 - 0.026 12.5 0.2 0.029 12.3 0.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Tektin PF03148.14 KXS98721.1 - 0.035 12.9 1.8 0.042 12.6 1.8 1.1 1 0 0 1 1 1 0 Tektin family APG6_N PF17675.1 KXS98721.1 - 0.036 14.6 4.1 0.047 14.2 4.1 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region Seryl_tRNA_N PF02403.22 KXS98721.1 - 0.045 14.0 2.6 0.062 13.5 2.3 1.4 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Prefoldin PF02996.17 KXS98721.1 - 0.049 13.6 1.2 0.066 13.1 1.2 1.4 1 1 0 1 1 1 0 Prefoldin subunit DASH_Spc19 PF08287.11 KXS98721.1 - 0.075 12.9 3.9 0.064 13.1 2.0 1.7 1 1 1 2 2 2 0 Spc19 TerB_C PF15615.6 KXS98721.1 - 0.12 12.7 3.9 0.16 12.2 3.7 1.4 1 1 0 1 1 1 0 TerB-C domain FlaC_arch PF05377.11 KXS98721.1 - 0.18 12.2 1.3 0.93 9.9 0.2 2.6 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) ZapB PF06005.12 KXS98721.1 - 0.26 11.8 4.2 0.48 10.9 2.6 2.1 1 1 1 2 2 2 0 Cell division protein ZapB DivIC PF04977.15 KXS98721.1 - 0.35 10.7 2.1 0.89 9.4 2.0 1.9 1 1 0 1 1 1 0 Septum formation initiator CENP-H PF05837.12 KXS98721.1 - 0.66 10.4 4.7 0.65 10.4 3.6 1.6 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Med21 PF11221.8 KXS98721.1 - 4.6 7.5 10.7 0.15 12.3 3.2 2.0 1 1 1 2 2 2 0 Subunit 21 of Mediator complex Sugar_tr PF00083.24 KXS98724.1 - 3.3e-100 336.1 19.2 3.9e-100 335.9 19.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS98724.1 - 1.9e-23 82.9 21.2 1.9e-23 82.9 21.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF997 PF06196.12 KXS98724.1 - 0.47 10.5 0.0 0.47 10.5 0.0 4.2 4 1 1 5 5 5 0 Protein of unknown function (DUF997) Aldo_ket_red PF00248.21 KXS98725.1 - 1.4e-44 152.5 0.0 3.4e-43 147.9 0.0 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family DHDPS PF00701.22 KXS98725.1 - 4.2e-37 127.4 0.0 5.8e-37 127.0 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Zn_clus PF00172.18 KXS98726.1 - 1.2e-08 34.9 9.2 2.2e-08 34.1 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXS98726.1 - 0.00023 20.3 0.2 0.0018 17.3 0.2 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain PLDc_2 PF13091.6 KXS98727.1 - 3.2e-15 56.2 0.1 0.0001 22.2 0.0 3.6 3 0 0 3 3 3 3 PLD-like domain PLDc PF00614.22 KXS98727.1 - 4.3e-15 55.2 2.9 7.6e-08 32.2 0.2 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif Vasculin PF15337.6 KXS98727.1 - 2.4 9.0 7.6 0.14 13.0 0.5 2.6 2 1 1 3 3 3 0 Vascular protein family Vasculin-like 1 Glyco_hydro_92 PF07971.12 KXS98728.1 - 9.1e-145 483.1 6.2 1.3e-144 482.6 6.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Thioredox_DsbH PF03190.15 KXS98728.1 - 2.8e-66 222.5 0.0 4.8e-66 221.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Glyco_hydro_92N PF17678.1 KXS98728.1 - 4.6e-58 196.9 4.4 4.6e-58 196.9 4.4 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 92 N-terminal domain Thioredoxin_7 PF13899.6 KXS98728.1 - 1e-06 28.8 0.0 2.7e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like Sigma70_r3 PF04539.16 KXS98728.1 - 0.081 13.0 0.2 0.26 11.4 0.1 1.8 2 0 0 2 2 2 0 Sigma-70 region 3 Sigma70_r4_2 PF08281.12 KXS98728.1 - 0.082 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 2-oxoacid_dh PF00198.23 KXS98729.1 - 3.6e-72 242.6 0.2 4.5e-72 242.3 0.2 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KXS98729.1 - 1.4e-17 63.2 1.4 1.9e-17 62.8 0.3 1.9 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 KXS98729.1 - 3.1e-10 40.2 1.1 3.1e-10 40.2 1.1 2.2 2 0 0 2 2 2 1 e3 binding domain CAS_CSE1 PF03378.15 KXS98730.1 - 3.4e-172 572.9 0.0 7.6e-172 571.8 0.0 1.6 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 KXS98730.1 - 1.2e-148 494.9 2.8 2.3e-148 493.9 2.8 1.5 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 KXS98730.1 - 6.1e-15 54.9 0.0 2.4e-14 53.0 0.0 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF4335 PF14233.6 KXS98730.1 - 0.099 12.6 0.1 0.39 10.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4335) Xpo1 PF08389.12 KXS98730.1 - 0.12 12.5 0.9 3.3 7.8 0.1 3.5 2 1 0 2 2 2 0 Exportin 1-like protein RNA_pol_Rpc4 PF05132.14 KXS98730.1 - 0.16 12.4 0.0 0.3 11.5 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Methyltransf_25 PF13649.6 KXS98731.1 - 1.7e-18 67.1 0.0 2.6e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS98731.1 - 3.6e-15 56.4 0.0 5.5e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS98731.1 - 2.8e-10 40.8 0.0 4.6e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS98731.1 - 3e-10 40.1 0.0 3.7e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXS98731.1 - 4.2e-10 39.7 0.0 5.8e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXS98731.1 - 1.1e-06 28.3 0.0 1.7e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain tRNA_U5-meth_tr PF05958.11 KXS98731.1 - 1.3e-06 27.6 0.0 1.8e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Ubie_methyltran PF01209.18 KXS98731.1 - 5.8e-06 25.8 0.0 1e-05 25.0 0.0 1.3 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family RrnaAD PF00398.20 KXS98731.1 - 2.8e-05 23.3 0.0 3.6e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase CMAS PF02353.20 KXS98731.1 - 3.7e-05 23.1 0.0 5e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.11 KXS98731.1 - 0.00079 19.1 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) CheR PF01739.18 KXS98731.1 - 0.0014 18.2 0.0 0.14 11.6 0.1 2.4 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain Methyltransf_16 PF10294.9 KXS98731.1 - 0.029 14.1 0.0 0.043 13.6 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase PrmA PF06325.13 KXS98731.1 - 0.04 13.3 0.0 0.054 12.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Pox_MCEL PF03291.16 KXS98731.1 - 0.21 10.7 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 mRNA capping enzyme BNR_2 PF13088.6 KXS98733.1 - 1.6e-67 227.7 0.6 1.9e-67 227.5 0.6 1.0 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 KXS98733.1 - 0.0021 17.7 18.3 0.29 11.3 0.2 4.7 5 0 0 5 5 5 3 BNR/Asp-box repeat BNR_4 PF15892.5 KXS98733.1 - 0.075 12.4 0.0 12 5.1 0.0 2.6 2 1 0 2 2 2 0 BNR repeat-containing family member Sortilin-Vps10 PF15902.5 KXS98733.1 - 0.11 11.3 3.4 5.1 5.8 0.0 2.9 3 0 0 3 3 3 0 Sortilin, neurotensin receptor 3, RRM_1 PF00076.22 KXS98734.1 - 1.5e-08 34.3 0.0 0.00086 19.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3866 PF12982.7 KXS98734.1 - 0.033 13.3 0.0 0.037 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3866) Sec7 PF01369.20 KXS98735.1 - 4e-74 248.3 2.0 1.9e-73 246.1 2.0 2.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KXS98735.1 - 1.2e-40 139.0 0.2 1.2e-40 139.0 0.2 2.8 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 KXS98735.1 - 1.5e-33 114.5 10.0 1.9e-31 107.7 0.0 6.0 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) DCB PF16213.5 KXS98735.1 - 2.5e-20 72.9 0.6 2.5e-20 72.9 0.6 3.0 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 Sugar_tr PF00083.24 KXS98736.1 - 0.071 12.0 0.0 0.078 11.8 0.0 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter WD40 PF00400.32 KXS98737.1 - 6.5e-19 67.9 1.7 0.0074 17.1 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS98737.1 - 2.8e-05 24.3 1.5 7.4 7.0 0.0 4.5 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KXS98737.1 - 9.7e-05 21.3 1.1 0.57 8.9 0.2 3.3 2 2 1 3 3 3 2 Nup133 N terminal like Nup160 PF11715.8 KXS98737.1 - 0.00012 20.9 1.2 0.31 9.6 0.0 3.6 1 1 1 4 4 4 2 Nucleoporin Nup120/160 DUF771 PF05595.11 KXS98737.1 - 0.046 13.7 0.0 0.86 9.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF771) Sigma70_r1_2 PF00140.20 KXS98737.1 - 0.047 13.7 1.0 0.11 12.6 1.0 1.6 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 PQQ_3 PF13570.6 KXS98737.1 - 0.091 13.3 0.0 0.94 10.0 0.0 2.6 2 1 1 3 3 3 0 PQQ-like domain FMN_dh PF01070.18 KXS98738.1 - 1.4e-111 372.9 0.3 1.7e-111 372.7 0.3 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KXS98738.1 - 6.6e-06 25.5 0.1 1e-05 24.9 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KXS98738.1 - 9.1e-05 21.6 0.0 0.0002 20.5 0.0 1.5 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KXS98738.1 - 0.0043 16.5 1.2 0.0064 15.9 0.6 1.4 1 1 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 KXS98738.1 - 0.017 14.4 1.3 0.24 10.7 0.1 2.5 2 1 1 3 3 3 0 Thiazole biosynthesis protein ThiG Asp PF00026.23 KXS98739.1 - 1.6e-68 231.5 14.0 2e-68 231.1 14.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXS98739.1 - 0.00011 22.5 6.7 0.005 17.1 4.0 3.2 1 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KXS98739.1 - 0.00014 22.4 1.4 0.029 15.0 1.3 3.1 2 1 0 2 2 2 1 Aspartyl protease Aminotran_5 PF00266.19 KXS98740.1 - 1e-19 70.7 0.0 3.9e-17 62.3 0.0 2.4 1 1 0 1 1 1 1 Aminotransferase class-V IL17 PF06083.11 KXS98741.1 - 0.09 13.3 1.2 0.33 11.5 0.3 2.2 2 0 0 2 2 2 0 Interleukin-17 Epimerase PF01370.21 KXS98742.1 - 5.5e-17 62.0 0.0 7.3e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXS98742.1 - 3.4e-11 43.1 0.0 6.9e-11 42.1 0.0 1.4 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KXS98742.1 - 1.1e-10 41.0 0.0 1.4e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KXS98742.1 - 7e-05 22.1 0.0 0.00011 21.4 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KXS98742.1 - 0.00015 21.1 0.0 0.051 12.7 0.0 2.4 2 1 0 2 2 2 2 Male sterility protein Ldh_1_N PF00056.23 KXS98742.1 - 0.0036 17.4 0.0 0.0056 16.8 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain adh_short PF00106.25 KXS98742.1 - 0.076 12.5 0.0 0.15 11.5 0.0 1.6 1 1 0 1 1 1 0 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 KXS98742.1 - 0.08 13.2 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF3684 PF12449.8 KXS98743.1 - 0 1389.2 0.0 0 1388.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) Methyltr_RsmB-F PF01189.17 KXS98743.1 - 4.3e-17 62.4 0.1 7.9e-12 45.2 0.0 2.6 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F HATPase_c_3 PF13589.6 KXS98743.1 - 1.6e-05 24.8 0.0 7.3e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CT_C_D PF02682.16 KXS98743.1 - 0.15 11.8 0.0 15 5.3 0.0 2.7 2 0 0 2 2 2 0 Carboxyltransferase domain, subdomain C and D Sugar_tr PF00083.24 KXS98745.1 - 2.5e-97 326.6 19.3 2.8e-97 326.4 19.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS98745.1 - 2.1e-25 89.4 15.7 2.1e-25 89.4 15.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KXS98745.1 - 0.00013 20.4 2.3 0.0002 19.8 2.3 1.2 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Aminotran_5 PF00266.19 KXS98746.1 - 2.5e-35 122.1 0.0 3.5e-35 121.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KXS98746.1 - 3.8e-06 25.7 0.0 6.4e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KXS98746.1 - 0.00096 18.4 0.0 0.004 16.4 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KXS98746.1 - 0.0042 16.5 0.0 0.36 10.1 0.0 2.0 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 KXS98746.1 - 0.044 13.0 0.0 0.061 12.6 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase DUF4400 PF14348.6 KXS98747.1 - 4.9 6.6 7.9 16 4.9 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4400) Acid_PPase PF12689.7 KXS98748.1 - 1.2e-60 204.2 0.0 1.4e-60 204.0 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase DUF2428 PF10350.9 KXS98749.1 - 2.4e-52 177.9 1.6 2.4e-52 177.9 1.6 2.4 3 0 0 3 3 3 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 KXS98749.1 - 0.16 12.3 10.2 11 6.6 0.1 5.9 6 0 0 6 6 6 0 HEAT repeat HEAT_2 PF13646.6 KXS98749.1 - 1.3 9.4 13.4 5.4 7.5 0.3 5.8 6 1 0 6 6 6 0 HEAT repeats Drf_GBD PF06371.13 KXS98750.1 - 3.8e-17 62.5 0.5 1e-08 35.0 0.0 2.6 2 0 0 2 2 2 2 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 KXS98750.1 - 0.0043 16.7 0.0 0.0091 15.6 0.0 1.5 1 0 0 1 1 1 1 Diaphanous FH3 Domain Flavoprotein PF02441.19 KXS98751.1 - 1.1e-48 165.0 0.1 3.8e-48 163.2 0.1 1.8 1 1 0 1 1 1 1 Flavoprotein WD40 PF00400.32 KXS98752.1 - 8.1e-41 137.2 16.8 1.2e-05 26.0 0.1 8.2 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 KXS98752.1 - 1.8e-09 37.4 0.0 3.5e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 KXS98752.1 - 5.6e-07 29.8 0.3 2.6 8.4 0.0 4.7 2 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 KXS98752.1 - 1.2e-06 28.2 0.0 2.3e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KXS98752.1 - 0.022 14.7 0.0 0.049 13.5 0.0 1.6 1 0 0 1 1 1 0 F-box Nup160 PF11715.8 KXS98752.1 - 0.027 13.2 5.1 12 4.4 0.0 4.6 4 1 0 5 5 5 0 Nucleoporin Nup120/160 PQQ_2 PF13360.6 KXS98752.1 - 0.059 12.9 3.0 2 7.9 1.3 3.1 1 1 1 2 2 2 0 PQQ-like domain Syntaxin_2 PF14523.6 KXS98753.1 - 2.8e-23 82.2 10.6 1.3e-21 76.9 0.2 2.7 3 0 0 3 3 3 2 Syntaxin-like protein SNARE PF05739.19 KXS98753.1 - 2.5e-13 49.8 1.6 2.5e-13 49.8 1.6 2.5 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.25 KXS98753.1 - 2.4e-05 24.1 8.6 0.00012 21.8 3.3 2.9 2 1 0 2 2 2 1 Syntaxin Synaptobrevin PF00957.21 KXS98753.1 - 0.0031 17.3 1.1 0.012 15.4 0.8 2.1 2 0 0 2 2 2 1 Synaptobrevin T7SS_ESX_EspC PF10824.8 KXS98753.1 - 0.01 16.3 2.5 0.014 15.8 0.2 2.3 2 1 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm DUF5345 PF17280.2 KXS98753.1 - 0.014 15.4 6.3 1.1 9.3 0.1 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5345) DUF883 PF05957.13 KXS98753.1 - 0.14 12.8 12.7 2.5 8.8 0.1 3.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF812 PF05667.11 KXS98753.1 - 0.19 10.6 11.5 0.4 9.5 11.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF812) UPF0242 PF06785.11 KXS98753.1 - 0.21 11.7 8.0 0.15 12.1 6.2 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Spectrin PF00435.21 KXS98753.1 - 0.21 12.1 8.1 1.1 9.8 6.7 2.6 2 1 0 2 2 2 0 Spectrin repeat Laminin_II PF06009.12 KXS98753.1 - 0.27 11.3 7.6 0.63 10.1 1.1 3.2 2 1 1 3 3 3 0 Laminin Domain II T3SSipB PF16535.5 KXS98753.1 - 0.37 11.3 15.7 0.27 11.7 7.8 2.9 2 1 1 3 3 3 0 Type III cell invasion protein SipB Prominin PF05478.11 KXS98753.1 - 1.4 6.8 6.8 4.5 5.1 6.3 2.0 1 1 0 1 1 1 0 Prominin DUF1664 PF07889.12 KXS98753.1 - 1.6 8.8 5.1 20 5.2 2.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Guanylate_kin PF00625.21 KXS98754.1 - 8.4e-63 211.3 0.1 2.7e-62 209.7 0.0 1.9 2 0 0 2 2 2 1 Guanylate kinase Zn_clus PF00172.18 KXS98754.1 - 1e-07 31.9 13.7 1.7e-07 31.2 13.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA_18 PF13238.6 KXS98754.1 - 1.1e-06 29.2 0.5 3.5e-06 27.6 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KXS98754.1 - 4.2e-06 27.0 0.1 4.1e-05 23.8 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXS98754.1 - 0.00011 22.6 0.1 0.00046 20.6 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 KXS98754.1 - 0.00013 22.0 0.0 0.00091 19.3 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_28 PF13521.6 KXS98754.1 - 0.00071 19.8 0.0 0.0069 16.7 0.0 2.5 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KXS98754.1 - 0.00085 19.9 0.0 0.0025 18.3 0.0 1.9 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 KXS98754.1 - 0.002 18.4 0.0 0.0048 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain dNK PF01712.19 KXS98754.1 - 0.0052 16.7 0.0 0.095 12.5 0.0 2.4 2 0 0 2 2 2 1 Deoxynucleoside kinase RsgA_GTPase PF03193.16 KXS98754.1 - 0.0073 16.2 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase Rad17 PF03215.15 KXS98754.1 - 0.025 14.5 0.0 0.054 13.4 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_29 PF13555.6 KXS98754.1 - 0.031 14.0 0.0 0.063 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 KXS98754.1 - 0.042 13.8 0.0 0.17 11.9 0.0 2.1 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KXS98754.1 - 0.043 14.2 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase CPT PF07931.12 KXS98754.1 - 0.078 12.8 0.0 0.21 11.4 0.0 1.6 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Viral_helicase1 PF01443.18 KXS98754.1 - 0.08 12.7 0.1 0.32 10.7 0.0 2.0 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 KXS98754.1 - 0.091 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_17 PF13207.6 KXS98754.1 - 0.1 13.0 1.9 0.48 10.8 0.0 3.1 3 1 0 3 3 2 0 AAA domain AAA_14 PF13173.6 KXS98754.1 - 0.14 12.2 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain EamA PF00892.20 KXS98755.1 - 3.1e-23 82.5 29.5 4.4e-12 46.3 7.1 2.2 2 0 0 2 2 2 2 EamA-like transporter family Fungal_trans PF04082.18 KXS98756.1 - 3.2e-11 42.8 0.0 6.3e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS98756.1 - 7.9e-08 32.3 8.9 1.5e-07 31.4 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MRP-S35 PF10246.9 KXS98756.1 - 0.089 12.8 0.0 2.1 8.3 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial ribosomal protein MRP-S35 RRM_1 PF00076.22 KXS98757.1 - 2.7e-17 62.3 0.0 6.9e-13 48.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXS98757.1 - 0.17 11.8 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif NUDE_C PF04880.13 KXS98758.1 - 4.7e-39 134.7 6.4 4.7e-39 134.7 6.4 4.0 2 2 1 4 4 1 1 NUDE protein, C-terminal conserved region ERM PF00769.19 KXS98758.1 - 0.0013 18.6 14.6 0.0013 18.6 14.6 2.2 1 1 1 2 2 2 2 Ezrin/radixin/moesin family LPP PF04728.13 KXS98758.1 - 0.016 15.6 0.6 0.016 15.6 0.6 2.7 2 0 0 2 2 2 0 Lipoprotein leucine-zipper DUF4795 PF16043.5 KXS98758.1 - 0.12 11.9 13.9 0.17 11.4 12.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) ZapB PF06005.12 KXS98758.1 - 1.1 9.8 31.7 0.14 12.6 2.5 4.7 2 1 2 4 4 4 0 Cell division protein ZapB GAS PF13851.6 KXS98758.1 - 1.4 8.3 29.6 58 2.9 23.8 2.7 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding FliD_N PF02465.18 KXS98758.1 - 1.5 9.6 10.1 0.24 12.1 2.0 2.9 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF745 PF05335.13 KXS98758.1 - 3.4 7.3 13.7 6.8 6.4 13.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Tropomyosin_1 PF12718.7 KXS98758.1 - 3.5 7.8 36.1 1.5 8.9 27.7 3.6 2 1 1 3 3 3 0 Tropomyosin like Chibby PF14645.6 KXS98758.1 - 3.8 8.0 12.9 0.98 9.8 6.9 2.4 1 1 1 2 2 2 0 Chibby family WXG100 PF06013.12 KXS98758.1 - 4.4 7.6 10.0 10 6.5 8.3 2.3 2 0 0 2 2 2 0 Proteins of 100 residues with WXG DUF4407 PF14362.6 KXS98758.1 - 6.2 6.1 13.6 12 5.1 13.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pkinase PF00069.25 KXS98759.1 - 1.4e-43 149.2 0.0 6.1e-43 147.1 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS98759.1 - 1.5e-27 96.6 0.0 2.1e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXS98759.1 - 0.00045 19.1 0.0 0.00057 18.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KXS98759.1 - 0.2 10.9 0.0 2.3 7.5 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Sugar_tr PF00083.24 KXS98760.1 - 8.2e-139 463.3 30.7 9.5e-139 463.1 30.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS98760.1 - 1.7e-23 83.1 40.2 4.4e-23 81.8 33.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Ebp2 PF05890.12 KXS98761.1 - 5.6e-96 321.2 22.0 5.6e-96 321.2 22.0 2.1 2 0 0 2 2 2 2 Eukaryotic rRNA processing protein EBP2 Pyridox_ox_2 PF12900.7 KXS98762.1 - 2.3e-35 121.6 0.0 3.1e-35 121.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Tim17 PF02466.19 KXS98765.1 - 3.5e-27 95.0 4.7 5.5e-27 94.3 4.7 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family 2_5_RNA_ligase2 PF13563.6 KXS98767.1 - 1.4e-11 44.5 0.0 2.2e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily DJ-1_PfpI PF01965.24 KXS98768.1 - 4.4e-11 42.9 0.0 8.4e-11 41.9 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KXS98768.1 - 5.1e-07 29.6 0.0 6.2e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 ThiJ/PfpI family-like Catalase_C PF18011.1 KXS98768.1 - 0.04 13.6 0.1 0.065 12.9 0.1 1.3 1 0 0 1 1 1 0 C-terminal domain found in long catalases BTB PF00651.31 KXS98769.1 - 2e-12 47.3 0.0 3.6e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Annexin PF00191.20 KXS98770.1 - 9.5e-72 237.0 12.3 2.9e-21 75.3 0.3 4.1 4 0 0 4 4 4 4 Annexin WW PF00397.26 KXS98770.1 - 9.1e-08 32.1 1.2 9.1e-08 32.1 1.2 1.9 2 0 0 2 2 2 1 WW domain Acetyltransf_11 PF13720.6 KXS98770.1 - 0.096 13.2 2.1 34 5.0 0.1 3.6 4 0 0 4 4 4 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 YlbE PF14003.6 KXS98770.1 - 0.14 12.6 5.9 16 6.0 0.6 3.7 3 0 0 3 3 3 0 YlbE-like protein Methyltransf_25 PF13649.6 KXS98771.1 - 3.7e-16 59.6 0.0 9e-16 58.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS98771.1 - 6e-14 52.5 0.0 1e-13 51.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXS98771.1 - 7.4e-14 51.9 0.0 9.4e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS98771.1 - 2.2e-12 47.5 0.0 3.2e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS98771.1 - 9.4e-09 35.2 0.0 1.2e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXS98771.1 - 5.1e-08 32.5 0.0 6.7e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Pox_MCEL PF03291.16 KXS98771.1 - 0.0012 18.1 0.0 0.0016 17.7 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme FtsJ PF01728.19 KXS98771.1 - 0.0016 18.6 0.0 0.0034 17.5 0.0 1.5 2 0 0 2 2 2 1 FtsJ-like methyltransferase MTS PF05175.14 KXS98771.1 - 0.013 15.1 0.0 0.047 13.3 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_9 PF08003.11 KXS98771.1 - 0.032 13.2 0.0 0.041 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 KXS98771.1 - 0.037 14.0 0.0 0.055 13.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain adh_short PF00106.25 KXS98772.1 - 7.6e-35 120.1 0.0 1e-34 119.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXS98772.1 - 1e-22 80.9 0.0 1.3e-22 80.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS98772.1 - 0.0012 18.7 0.0 0.0025 17.8 0.0 1.5 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KXS98772.1 - 0.059 13.3 0.0 0.097 12.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F-box-like_2 PF13013.6 KXS98773.1 - 0.08 12.9 0.1 0.19 11.7 0.1 1.7 1 1 0 1 1 1 0 F-box-like domain 4HBT PF03061.22 KXS98774.1 - 3.1e-13 49.9 0.0 5.2e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 KXS98774.1 - 0.021 15.1 0.0 0.027 14.7 0.0 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily WD40 PF00400.32 KXS98775.1 - 9.1e-26 89.6 11.5 1.4e-07 32.1 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS98775.1 - 4.9e-07 30.0 0.0 0.25 11.7 0.0 3.9 3 2 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXS98775.1 - 0.00071 18.6 0.0 0.062 12.2 0.0 2.7 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KXS98775.1 - 0.012 14.3 0.0 0.58 8.7 0.0 2.5 2 1 0 3 3 3 0 Nucleoporin Nup120/160 Proteasome_A_N PF10584.9 KXS98775.1 - 0.053 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature COX7a PF02238.15 KXS98776.1 - 3.1e-24 85.1 0.9 3.9e-24 84.8 0.9 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII Isochorismatase PF00857.20 KXS98778.1 - 2.6e-10 40.8 0.0 4.1e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family Myb_DNA-binding PF00249.31 KXS98779.1 - 6.2e-10 39.1 4.3 5.9e-05 23.2 0.1 3.4 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXS98779.1 - 1.4e-08 34.8 0.3 0.00031 20.9 0.0 3.2 2 1 1 3 3 3 2 Myb-like DNA-binding domain HTH_38 PF13936.6 KXS98779.1 - 0.00053 19.7 1.2 0.0013 18.4 0.1 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain Terminase_5 PF06056.12 KXS98779.1 - 0.03 14.2 0.1 0.073 13.0 0.1 1.7 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) HTH_11 PF08279.12 KXS98779.1 - 0.05 13.5 0.1 0.34 10.9 0.0 2.3 2 0 0 2 2 2 0 HTH domain HTH_32 PF13565.6 KXS98779.1 - 0.056 14.1 6.3 0.079 13.6 0.2 2.8 1 1 2 3 3 3 0 Homeodomain-like domain HTH_23 PF13384.6 KXS98779.1 - 0.058 13.2 0.0 0.18 11.7 0.0 1.9 1 0 0 1 1 1 0 Homeodomain-like domain Sigma70_r4_2 PF08281.12 KXS98779.1 - 0.064 12.9 0.3 0.33 10.7 0.0 2.3 3 0 0 3 3 3 0 Sigma-70, region 4 Rap1_C PF11626.8 KXS98779.1 - 0.11 12.5 1.3 0.9 9.7 1.3 2.1 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain COesterase PF00135.28 KXS98780.1 - 2.3e-69 234.7 0.0 2.6e-69 234.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXS98780.1 - 3.2e-05 23.9 0.2 0.0054 16.6 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold PPR_2 PF13041.6 KXS98781.1 - 0.018 15.2 0.0 0.051 13.8 0.0 1.8 2 0 0 2 2 2 0 PPR repeat family Peptidase_S24 PF00717.23 KXS98782.1 - 4.5e-08 32.9 0.0 7.4e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 KXS98782.1 - 5.9e-05 22.9 0.0 0.0025 17.6 0.0 2.4 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 Amidoligase_2 PF12224.8 KXS98783.1 - 1.2e-10 41.6 0.1 1.3e-06 28.3 0.2 2.7 3 0 0 3 3 3 2 Putative amidoligase enzyme ACC_central PF08326.12 KXS98785.1 - 4.8e-273 907.8 0.0 6.2e-273 907.4 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 KXS98785.1 - 1e-183 611.6 0.0 1.4e-183 611.1 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 KXS98785.1 - 1.6e-52 178.1 0.1 3.3e-52 177.0 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KXS98785.1 - 1e-27 96.9 0.1 2.5e-27 95.6 0.1 1.8 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KXS98785.1 - 1.5e-22 79.8 0.0 9.8e-21 73.9 0.0 2.7 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KXS98785.1 - 2.9e-17 62.3 0.2 9.3e-17 60.6 0.2 2.0 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KXS98785.1 - 4.6e-05 23.0 0.1 0.00015 21.3 0.1 1.9 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 KXS98785.1 - 0.00029 20.9 0.1 0.0013 18.8 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain GxGYxYP_N PF16216.5 KXS98785.1 - 0.0031 17.7 0.1 0.0081 16.4 0.1 1.6 1 0 0 1 1 1 1 GxGYxY sequence motif in domain of unknown function N-terminal ATP-grasp PF02222.22 KXS98785.1 - 0.0042 16.7 0.0 0.01 15.4 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 KXS98785.1 - 0.0068 16.2 0.0 0.019 14.8 0.0 1.7 1 0 0 1 1 1 1 Biotin-lipoyl like Antiterm PF03589.13 KXS98785.1 - 0.1 12.9 0.0 0.79 10.1 0.0 2.4 2 0 0 2 2 2 0 Antitermination protein Ribonuclease PF00545.20 KXS98792.1 - 9.1e-09 36.0 0.7 1.5e-08 35.3 0.5 1.5 1 1 0 1 1 1 1 ribonuclease SMC_N PF02463.19 KXS98793.1 - 3.5e-70 235.9 9.3 1.2e-69 234.1 9.3 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KXS98793.1 - 6.2e-29 100.7 0.0 3.1e-28 98.4 0.0 2.4 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KXS98793.1 - 2.2e-17 63.8 14.2 6.5e-12 45.9 0.2 3.7 4 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KXS98793.1 - 2e-15 57.4 59.5 1.8e-09 37.8 27.2 4.4 2 2 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 KXS98793.1 - 2.5e-07 31.4 120.2 1.8e+04 -5.1 15.7 7.8 1 1 1 2 2 0 0 AAA domain APG6_N PF17675.1 KXS98793.1 - 3.1e-05 24.5 127.5 0.12 12.8 16.2 7.7 3 3 4 7 7 7 5 Apg6 coiled-coil region AAA_29 PF13555.6 KXS98793.1 - 0.0056 16.4 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran_CTD PF16326.5 KXS98793.1 - 0.01 16.1 4.9 0.01 16.1 4.9 11.5 4 3 7 12 12 9 0 ABC transporter C-terminal domain SbcCD_C PF13558.6 KXS98793.1 - 0.051 13.8 0.0 0.17 12.2 0.0 1.9 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.6 KXS98793.1 - 0.21 10.2 85.8 0.059 12.0 4.1 6.4 5 1 1 6 6 6 0 AAA domain DUF4407 PF14362.6 KXS98793.1 - 0.27 10.6 100.8 0.51 9.6 15.6 7.0 3 2 4 7 7 7 0 Domain of unknown function (DUF4407) DUF87 PF01935.17 KXS98793.1 - 2.4 8.2 0.0 2.4 8.2 0.0 6.9 4 3 1 5 5 3 0 Helicase HerA, central domain DUF3584 PF12128.8 KXS98793.1 - 4.1 4.8 114.1 0.0097 13.5 44.4 4.3 2 2 2 4 4 4 0 Protein of unknown function (DUF3584) MscS_porin PF12795.7 KXS98793.1 - 5.5 6.5 110.4 0.07 12.7 20.2 6.3 2 2 4 6 6 6 0 Mechanosensitive ion channel porin domain DUF1664 PF07889.12 KXS98793.1 - 5.9 7.0 67.5 0.74 9.9 5.6 9.0 3 2 7 11 11 11 0 Protein of unknown function (DUF1664) FMO-like PF00743.19 KXS98794.1 - 1.3e-20 73.3 0.0 6.6e-17 61.1 0.0 2.6 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXS98794.1 - 1.5e-20 73.7 0.0 2.6e-19 69.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXS98794.1 - 6e-13 48.7 0.0 2.5e-09 36.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXS98794.1 - 1e-12 47.9 0.0 1.8e-10 40.5 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KXS98794.1 - 7.3e-08 32.4 0.0 0.013 15.1 0.0 2.9 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXS98794.1 - 9.1e-06 25.7 0.1 0.093 12.7 0.0 3.2 2 1 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KXS98794.1 - 1.9e-05 24.8 0.0 0.00019 21.6 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXS98794.1 - 0.00073 18.9 0.3 0.0018 17.6 0.0 1.7 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 KXS98794.1 - 0.0032 18.0 1.8 0.58 10.7 0.2 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXS98794.1 - 0.017 14.2 0.3 0.32 10.0 0.0 2.9 3 1 0 3 3 3 0 Lycopene cyclase protein HI0933_like PF03486.14 KXS98794.1 - 0.066 11.9 0.0 12 4.5 0.0 2.6 3 0 0 3 3 3 0 HI0933-like protein Mqo PF06039.15 KXS98794.1 - 0.093 11.3 0.0 10 4.6 0.0 2.2 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) FAD_binding_2 PF00890.24 KXS98794.1 - 0.2 10.7 0.0 0.44 9.6 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.22 KXS98794.1 - 0.35 9.9 2.0 34 3.3 0.1 3.4 4 0 0 4 4 4 0 Glucose inhibited division protein A F-box PF00646.33 KXS98795.1 - 2.9e-05 23.8 0.1 6.2e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXS98795.1 - 0.00096 19.0 0.1 0.0016 18.3 0.1 1.4 1 0 0 1 1 1 1 F-box-like DUF1421 PF07223.11 KXS98795.1 - 0.11 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain (DUF1421) ADH_N PF08240.12 KXS98796.1 - 7.5e-07 29.0 0.0 8.9e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Suc_Fer-like PF06999.12 KXS98796.1 - 0.18 11.7 0.9 0.21 11.5 0.9 1.2 1 1 0 1 1 1 0 Sucrase/ferredoxin-like SH3_1 PF00018.28 KXS98797.1 - 2.7e-09 36.5 0.1 5.6e-09 35.5 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXS98797.1 - 1.2e-06 28.3 0.0 2.7e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KXS98797.1 - 2.7e-06 27.0 0.0 6e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain ThrE PF06738.12 KXS98797.1 - 0.027 13.9 4.4 0.039 13.3 4.4 1.2 1 0 0 1 1 1 0 Putative threonine/serine exporter DUF2070 PF09843.9 KXS98797.1 - 0.041 12.2 3.5 0.053 11.8 3.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF2303 PF10065.9 KXS98797.1 - 0.15 11.2 0.1 0.25 10.5 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2303) Consortin_C PF15281.6 KXS98797.1 - 0.18 11.8 0.2 0.32 11.0 0.2 1.3 1 0 0 1 1 1 0 Consortin C-terminus Pkinase PF00069.25 KXS98798.1 - 2.7e-72 243.3 0.0 3.9e-72 242.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS98798.1 - 1.6e-37 129.2 0.0 2.7e-37 128.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase ApbA PF02558.16 KXS98798.1 - 2.4e-31 108.4 0.0 4.4e-31 107.6 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KXS98798.1 - 1.4e-22 80.2 0.0 6.8e-22 78.0 0.0 2.0 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal Kinase-like PF14531.6 KXS98798.1 - 0.0007 19.0 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like GFO_IDH_MocA PF01408.22 KXS98798.1 - 0.048 14.5 0.0 0.82 10.5 0.0 2.5 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Acyltransferase PF01553.21 KXS98799.1 - 0.061 12.9 0.0 0.42 10.2 0.0 2.2 2 1 0 2 2 2 0 Acyltransferase DUF3632 PF12311.8 KXS98800.1 - 4.1e-36 125.0 6.6 6e-36 124.5 6.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) SNO PF01174.19 KXS98801.1 - 2.1e-54 184.2 0.0 3.1e-43 147.8 0.0 2.8 2 1 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 KXS98801.1 - 6.8e-11 42.1 0.0 5.9e-09 35.8 0.0 2.1 2 0 0 2 2 2 2 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 KXS98801.1 - 0.0018 18.1 0.0 0.026 14.3 0.0 2.2 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.24 KXS98801.1 - 0.0021 17.9 0.0 0.0032 17.3 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family Peptidase_S51 PF03575.17 KXS98801.1 - 0.013 15.1 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S51 ThiJ_like PF17124.5 KXS98801.1 - 0.043 13.5 0.0 0.066 12.9 0.0 1.3 1 0 0 1 1 1 0 ThiJ/PfpI family-like Lyase_1 PF00206.20 KXS98802.1 - 1.9e-37 129.3 0.1 5.9e-37 127.7 0.1 1.6 1 1 0 1 1 1 1 Lyase ADSL_C PF10397.9 KXS98802.1 - 2.9e-20 72.6 0.0 7.9e-20 71.2 0.0 1.8 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus ASL_C PF08328.11 KXS98802.1 - 0.0029 17.7 0.0 0.0076 16.3 0.0 1.8 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminal HTH_24 PF13412.6 KXS98802.1 - 0.13 11.8 0.3 0.36 10.4 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding DUF4267 PF14087.6 KXS98804.1 - 6.3e-17 61.7 0.2 7.4e-17 61.4 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) EMC1_C PF07774.13 KXS98805.1 - 1.8e-75 253.3 0.0 3.1e-75 252.5 0.0 1.4 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 KXS98805.1 - 2.3e-24 86.3 9.6 1.3e-23 83.9 1.4 3.0 2 1 1 3 3 3 2 PQQ-like domain PQQ PF01011.21 KXS98805.1 - 9e-10 38.0 0.4 0.091 12.7 0.0 4.8 4 0 0 4 4 4 3 PQQ enzyme repeat Lyase_1 PF00206.20 KXS98806.1 - 1.8e-23 83.4 0.0 3e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 KXS98806.1 - 3e-16 59.7 0.0 8.3e-16 58.3 0.0 1.8 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Amidohydro_1 PF01979.20 KXS98806.1 - 0.065 12.5 0.0 0.23 10.7 0.0 1.7 1 1 0 1 1 1 0 Amidohydrolase family Acetyltransf_2 PF00797.17 KXS98807.1 - 2.4e-38 132.3 0.3 4.7e-37 128.1 0.3 2.0 2 0 0 2 2 2 2 N-acetyltransferase DUF2439 PF10382.9 KXS98808.1 - 1e-26 93.1 0.0 1.8e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) RRM_1 PF00076.22 KXS98809.1 - 5.4e-15 55.0 0.0 7.9e-15 54.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ACPS PF01648.20 KXS98810.1 - 3.1e-06 27.3 0.0 1.7e-05 24.9 0.0 2.1 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily WHAMM-JMY_N PF15920.5 KXS98810.1 - 0.3 11.0 1.3 0.55 10.1 0.3 2.0 2 1 0 2 2 2 0 N-terminal of Junction-mediating and WASP homolog-associated SNase PF00565.17 KXS98813.1 - 2.8e-78 259.4 0.0 6.2e-26 91.0 0.0 5.9 6 0 0 6 6 6 5 Staphylococcal nuclease homologue adh_short_C2 PF13561.6 KXS98813.1 - 9.7e-29 100.6 0.2 8.1e-28 97.6 0.0 2.2 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase TUDOR PF00567.24 KXS98813.1 - 6e-18 65.0 0.0 2.9e-17 62.8 0.0 2.1 2 0 0 2 2 2 1 Tudor domain adh_short PF00106.25 KXS98813.1 - 4.7e-16 58.8 0.0 3.9e-14 52.5 0.0 2.6 1 1 1 2 2 2 1 short chain dehydrogenase SMN PF06003.12 KXS98813.1 - 8.9e-06 25.1 0.0 1.6e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) Agenet PF05641.12 KXS98813.1 - 0.13 12.8 0.1 0.38 11.2 0.1 1.8 1 0 0 1 1 1 0 Agenet domain UCH PF00443.29 KXS98814.1 - 5.2e-34 117.9 0.0 2.3e-33 115.8 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXS98814.1 - 3.6e-10 40.0 0.7 4.3e-08 33.1 0.0 3.4 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase DUF3517 PF12030.8 KXS98814.1 - 1.4e-09 37.3 0.0 1.9e-08 33.6 0.0 2.9 3 1 0 3 3 3 1 Domain of unknown function (DUF3517) TPR_5 PF12688.7 KXS98814.1 - 0.0025 18.1 0.6 0.027 14.7 0.2 2.6 2 0 0 2 2 2 1 Tetratrico peptide repeat GlnD_UR_UTase PF08335.11 KXS98814.1 - 0.055 13.6 3.8 0.074 13.1 1.9 2.2 2 0 0 2 2 2 0 GlnD PII-uridylyltransferase Nup88 PF10168.9 KXS98815.1 - 3.5e-07 28.5 8.9 0.11 10.3 0.0 3.3 3 0 0 3 3 3 3 Nuclear pore component SF-assemblin PF06705.11 KXS98815.1 - 0.036 13.4 7.1 0.017 14.5 4.3 1.8 2 0 0 2 2 2 0 SF-assemblin/beta giardin WXG100 PF06013.12 KXS98815.1 - 0.093 13.0 1.5 0.69 10.2 0.1 2.9 3 0 0 3 3 3 0 Proteins of 100 residues with WXG Spectrin PF00435.21 KXS98815.1 - 0.22 12.0 10.7 2.7 8.5 0.1 3.9 4 0 0 4 4 4 0 Spectrin repeat DUF948 PF06103.11 KXS98815.1 - 0.32 11.3 3.5 8.3 6.7 0.0 3.8 4 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) cwf21 PF08312.12 KXS98815.1 - 0.57 10.4 4.1 12 6.2 1.5 2.7 2 0 0 2 2 2 0 cwf21 domain FapA PF03961.13 KXS98815.1 - 0.72 8.4 6.9 0.37 9.3 3.1 1.7 1 1 1 2 2 2 0 Flagellar Assembly Protein A OmpH PF03938.14 KXS98815.1 - 1 9.7 6.5 1.8 8.9 1.1 2.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF1664 PF07889.12 KXS98815.1 - 3.7 7.6 6.3 45 4.1 0.3 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Nup54 PF13874.6 KXS98815.1 - 3.9 7.6 8.5 1.6 8.9 4.1 2.3 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 GrpE PF01025.19 KXS98815.1 - 7.2 6.3 7.6 6.5 6.4 5.1 2.1 1 1 1 2 2 2 0 GrpE TAL_FSA PF00923.19 KXS98816.1 - 1.3e-95 320.0 2.1 1.5e-95 319.8 2.1 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase C5-epim_C PF06662.13 KXS98816.1 - 0.03 13.8 0.0 0.055 13.0 0.0 1.4 1 0 0 1 1 1 0 D-glucuronyl C5-epimerase C-terminus MFS_1 PF07690.16 KXS98817.1 - 2.9e-34 118.5 35.6 2.9e-34 118.5 35.6 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4231 PF14015.6 KXS98817.1 - 0.14 12.7 3.1 1.6 9.2 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) DUF3605 PF12239.8 KXS98818.1 - 3.4e-57 193.1 0.3 4e-57 192.8 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) SLD5_C PF16922.5 KXS98819.1 - 6.1e-14 51.9 0.3 1.1e-13 51.2 0.3 1.4 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 KXS98819.1 - 1.1e-05 25.8 0.1 2.1e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 GINS complex protein adh_short_C2 PF13561.6 KXS98820.1 - 8.9e-62 208.7 1.0 1.2e-61 208.3 1.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS98820.1 - 2.2e-46 157.8 1.2 2.9e-46 157.4 1.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS98820.1 - 8e-17 61.7 0.2 1.6e-16 60.7 0.2 1.5 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 KXS98820.1 - 0.031 13.3 0.1 0.043 12.8 0.1 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KXS98820.1 - 0.14 11.5 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase SSF PF00474.17 KXS98822.1 - 2.3e-18 66.3 28.1 3.7e-18 65.6 28.1 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family PsbI PF02532.14 KXS98822.1 - 0.091 12.7 1.1 0.5 10.3 1.1 2.3 1 0 0 1 1 1 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) DUF3278 PF11683.8 KXS98822.1 - 4.3 7.4 16.4 0.62 10.2 0.2 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3278) Ras PF00071.22 KXS98824.1 - 4.3e-22 78.4 0.1 5e-22 78.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXS98824.1 - 3.9e-11 43.2 0.0 4.3e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KXS98824.1 - 0.017 15.2 0.0 0.019 15.0 0.0 1.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase Arf PF00025.21 KXS98824.1 - 0.038 13.5 0.0 0.038 13.4 0.0 1.0 1 0 0 1 1 1 0 ADP-ribosylation factor family DUF87 PF01935.17 KXS98824.1 - 0.039 14.0 0.2 0.06 13.4 0.2 1.3 1 1 0 1 1 1 0 Helicase HerA, central domain Ras PF00071.22 KXS98825.1 - 4.1e-19 68.7 0.1 5.4e-19 68.4 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXS98825.1 - 8.1e-11 42.2 0.0 1e-10 41.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 KXS98825.1 - 0.019 14.3 0.0 0.021 14.1 0.0 1.0 1 0 0 1 1 1 0 Septin DUF87 PF01935.17 KXS98825.1 - 0.041 14.0 0.3 0.058 13.5 0.3 1.4 1 1 0 1 1 1 0 Helicase HerA, central domain ATPase PF06745.13 KXS98825.1 - 0.07 12.5 0.5 0.17 11.2 0.1 1.7 1 1 1 2 2 2 0 KaiC MMR_HSR1 PF01926.23 KXS98825.1 - 0.089 12.9 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase FAD_binding_6 PF00970.24 KXS98826.1 - 5.1e-29 100.5 0.1 1.2e-28 99.4 0.1 1.6 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KXS98826.1 - 3.4e-25 88.8 0.0 5e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KXS98826.1 - 0.0047 17.1 0.0 0.12 12.5 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 KXS98827.1 - 5.1e-29 100.5 0.1 1.2e-28 99.4 0.1 1.6 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KXS98827.1 - 3.4e-25 88.8 0.0 5e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KXS98827.1 - 0.0047 17.1 0.0 0.12 12.5 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Kinesin PF00225.23 KXS98828.1 - 1.7e-83 280.3 11.5 2.5e-47 161.5 1.7 3.5 3 0 0 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 KXS98828.1 - 3.1e-46 157.0 0.1 1.7e-45 154.6 0.0 2.2 2 0 0 2 2 2 1 Microtubule binding Macoilin PF09726.9 KXS98828.1 - 0.086 11.4 43.9 0.05 12.2 30.7 2.3 1 1 1 2 2 2 0 Macoilin family Filament PF00038.21 KXS98828.1 - 0.5 9.9 43.7 85 2.6 31.5 3.3 1 1 1 2 2 2 0 Intermediate filament protein Baculo_PEP_C PF04513.12 KXS98828.1 - 1.3 9.0 15.3 0.3 11.1 3.7 3.6 3 2 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 KXS98828.1 - 1.4 7.8 45.3 0.22 10.4 13.9 2.8 1 1 2 3 3 3 0 Spc7 kinetochore protein RasGAP_C PF03836.15 KXS98828.1 - 4.6 7.4 17.5 0.78 9.9 7.7 3.4 3 1 0 3 3 3 0 RasGAP C-terminus HET PF06985.11 KXS98829.1 - 6.7e-32 110.9 0.1 1.9e-31 109.4 0.0 1.8 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 KXS98830.1 - 6.7e-32 110.9 0.1 1.9e-31 109.4 0.0 1.8 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF2401 PF10287.9 KXS98837.1 - 3.6e-93 311.4 0.8 3.6e-93 311.4 0.8 1.7 2 0 0 2 2 2 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 KXS98837.1 - 5.3e-27 94.0 0.4 1.5e-26 92.6 0.4 1.8 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) Peroxin-13_N PF04088.13 KXS98838.1 - 4e-53 179.6 0.3 7e-53 178.8 0.3 1.4 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 KXS98838.1 - 6.9e-09 35.3 0.0 1.2e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXS98838.1 - 2.1e-07 30.4 0.0 4.8e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 SH3 domain Pex2_Pex12 PF04757.14 KXS98838.1 - 0.16 11.5 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region GRP PF07172.11 KXS98838.1 - 1.6 9.5 20.6 3.5 8.4 20.6 1.6 1 0 0 1 1 1 0 Glycine rich protein family SRR1 PF07985.12 KXS98841.1 - 1.6e-13 50.5 0.0 3e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 SRR1 Nramp PF01566.18 KXS98842.1 - 3.3e-84 282.9 13.7 3.3e-84 282.9 13.7 2.5 2 1 0 2 2 2 1 Natural resistance-associated macrophage protein TMEM156 PF15106.6 KXS98842.1 - 0.42 10.0 4.3 0.72 9.2 4.3 1.3 1 0 0 1 1 1 0 TMEM156 protein family F-box-like PF12937.7 KXS98843.1 - 5.9e-05 22.9 0.7 5.9e-05 22.9 0.7 2.1 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KXS98843.1 - 6.1e-05 22.8 0.1 0.00013 21.8 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KXS98843.1 - 0.047 13.6 0.0 0.19 11.6 0.0 2.1 2 0 0 2 2 2 0 F-box Dpy-30 PF05186.13 KXS98844.1 - 5.7e-13 48.3 0.6 1.8e-12 46.8 0.2 1.9 2 0 0 2 2 2 1 Dpy-30 motif MCPVI PF02993.14 KXS98844.1 - 1.7 8.5 5.8 1.9 8.2 5.8 1.1 1 0 0 1 1 1 0 Minor capsid protein VI SNARE_assoc PF09335.11 KXS98845.1 - 3.8e-14 53.2 5.7 3.8e-14 53.2 5.7 2.1 2 0 0 2 2 2 1 SNARE associated Golgi protein Complex1_49kDa PF00346.19 KXS98846.1 - 3.5e-123 410.0 0.0 4.9e-123 409.5 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 KXS98846.1 - 0.014 14.4 0.0 0.02 13.8 0.0 1.3 1 0 0 1 1 1 0 Nickel-dependent hydrogenase TPR_12 PF13424.6 KXS98847.1 - 8e-05 22.9 1.8 0.00096 19.4 0.3 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KXS98847.1 - 0.00047 19.6 0.2 0.00093 18.7 0.2 1.4 1 0 0 1 1 1 1 MalT-like TPR region TPR_1 PF00515.28 KXS98847.1 - 0.0035 17.1 0.4 0.057 13.3 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXS98847.1 - 0.0053 16.7 0.1 0.22 11.6 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXS98847.1 - 0.055 14.0 0.2 0.52 10.8 0.2 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat ANAPC5 PF12862.7 KXS98847.1 - 0.061 13.4 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 TPR_14 PF13428.6 KXS98847.1 - 0.087 13.7 0.1 0.64 11.0 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXS98847.1 - 0.092 12.9 0.1 0.092 12.9 0.1 2.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXS98847.1 - 0.14 12.0 3.9 0.17 11.8 0.1 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXS98847.1 - 0.17 12.2 0.1 0.8 10.1 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Amino_oxidase PF01593.24 KXS98849.1 - 3.3e-79 267.3 0.0 4.8e-66 223.9 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase SWIRM PF04433.17 KXS98849.1 - 4.4e-15 55.8 0.0 8.6e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain NAD_binding_8 PF13450.6 KXS98849.1 - 8.1e-07 29.2 0.0 2.5e-06 27.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXS98849.1 - 0.00014 21.6 1.3 0.00031 20.4 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase HMG_box PF00505.19 KXS98849.1 - 0.0002 21.7 5.3 0.0017 18.7 0.6 2.5 1 1 1 2 2 2 1 HMG (high mobility group) box Pyr_redox_2 PF07992.14 KXS98849.1 - 0.0037 16.5 0.0 0.019 14.2 0.0 2.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thiolase_N PF00108.23 KXS98850.1 - 7.5e-14 51.7 0.0 4.2e-13 49.3 0.0 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXS98850.1 - 4e-12 45.9 0.3 3e-11 43.0 0.3 2.4 1 1 1 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 KXS98850.1 - 1.1e-05 25.2 0.0 0.00043 20.1 0.0 2.4 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 KXS98850.1 - 0.0012 18.5 0.2 0.0063 16.1 0.1 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KXS98850.1 - 0.016 15.2 0.3 1.6 8.8 0.0 3.2 3 0 0 3 3 3 0 Beta-ketoacyl synthase, C-terminal domain SpoVAD PF07451.11 KXS98850.1 - 0.02 13.6 0.1 0.052 12.2 0.1 1.6 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) Peroxidase_2 PF01328.17 KXS98853.1 - 1.8e-44 152.5 0.0 2.6e-44 152.0 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Peptidase_S8 PF00082.22 KXS98854.1 - 2.7e-35 122.1 17.0 5.2e-35 121.1 17.0 1.4 1 1 0 1 1 1 1 Subtilase family HMMR_N PF15905.5 KXS98855.1 - 9.8 5.5 6.1 16 4.9 6.1 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal F_actin_cap_B PF01115.17 KXS98857.1 - 2e-93 312.4 0.0 3e-93 311.9 0.0 1.2 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Metallophos PF00149.28 KXS98860.1 - 1.5e-15 58.3 1.3 2.4e-15 57.6 1.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase BRO1 PF03097.18 KXS98861.1 - 8.5e-124 413.3 0.2 8.5e-124 413.3 0.2 2.2 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KXS98861.1 - 1.6e-80 270.6 15.2 1.6e-80 270.6 15.2 2.1 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV DRE2_N PF16803.5 KXS98861.1 - 0.28 11.4 1.5 40 4.5 0.0 3.4 3 0 0 3 3 3 0 Fe-S cluster assembly protein DRE2 N-terminus DUF4281 PF14108.6 KXS98863.1 - 0.061 13.7 0.5 0.061 13.7 0.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4281) 7tm_6 PF02949.20 KXS98863.1 - 0.12 11.4 3.0 0.18 10.9 3.0 1.3 1 1 0 1 1 1 0 7tm Odorant receptor Tetraspanin PF00335.20 KXS98863.1 - 3.2 7.4 7.6 9.7 5.8 7.6 1.9 1 1 0 1 1 1 0 Tetraspanin family Methyltransf_16 PF10294.9 KXS98864.1 - 4.8e-15 55.7 0.1 2.6e-14 53.3 0.1 1.9 1 1 0 1 1 1 1 Lysine methyltransferase Pkinase PF00069.25 KXS98865.1 - 8.9e-14 51.5 0.0 1.2e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS98865.1 - 0.00069 19.0 0.0 0.00098 18.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase E1_DerP2_DerF2 PF02221.15 KXS98866.1 - 1.8e-27 96.4 0.5 2.2e-27 96.1 0.5 1.1 1 0 0 1 1 1 1 ML domain Big_9 PF17963.1 KXS98866.1 - 0.096 13.4 0.9 0.18 12.5 0.3 1.8 2 0 0 2 2 2 0 Bacterial Ig domain Pec_lyase_C PF00544.19 KXS98868.1 - 1.9e-42 145.2 8.4 2.7e-42 144.8 8.4 1.2 1 0 0 1 1 1 1 Pectate lyase Glyco_hydro_65m PF03632.15 KXS98868.1 - 0.005 15.7 0.0 0.0077 15.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain HMA PF00403.26 KXS98870.1 - 3e-18 66.0 0.8 3.5e-18 65.8 0.8 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain DUF148 PF02520.17 KXS98870.1 - 0.075 13.1 0.0 0.083 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF148 DHHA2 PF02833.14 KXS98871.1 - 2.5e-16 60.2 0.1 4.6e-16 59.3 0.1 1.5 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 KXS98871.1 - 1.8e-07 31.3 0.0 3.3e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 DHH family Phage_holin_2_4 PF16082.5 KXS98873.1 - 0.035 13.8 4.4 4.3 7.1 0.1 3.1 2 2 1 3 3 3 0 Bacteriophage holin family, superfamily II-like ATP-synt_F PF01990.17 KXS98874.1 - 1.2e-31 108.9 0.1 1.4e-31 108.7 0.1 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit Hce2 PF14856.6 KXS98875.1 - 1.5e-21 76.6 0.3 2.6e-21 75.8 0.3 1.5 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor VPS13_mid_rpt PF16910.5 KXS98876.1 - 1e-98 329.5 25.3 8.1e-96 320.0 5.3 6.5 7 0 0 7 7 7 3 Repeating coiled region of VPS13 SHR-BD PF06650.12 KXS98876.1 - 1.5e-94 316.4 0.0 1.3e-93 313.3 0.0 2.5 2 0 0 2 2 2 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13 PF16908.5 KXS98876.1 - 3.4e-85 285.6 9.2 3e-84 282.5 0.0 4.8 5 0 0 5 5 5 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 KXS98876.1 - 5.3e-74 247.8 3.8 1.8e-68 229.8 0.2 2.8 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 KXS98876.1 - 8.8e-41 138.7 0.1 3.9e-40 136.6 0.1 2.3 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 KXS98876.1 - 8.3e-06 26.1 0.0 0.00021 21.6 0.0 2.8 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain DUF896 PF05979.12 KXS98876.1 - 0.53 10.2 7.9 1.5 8.8 0.8 3.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) Tyrosinase PF00264.20 KXS98877.1 - 2e-52 178.7 0.9 3.5e-52 177.9 0.9 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 KXS98877.1 - 2.3e-27 96.1 0.0 7.2e-27 94.5 0.0 1.9 2 0 0 2 2 2 1 Tyosinase C-terminal domain GHMP_kinases_N PF00288.26 KXS98877.1 - 0.013 15.7 2.8 0.072 13.3 2.8 2.3 1 0 0 1 1 1 0 GHMP kinases N terminal domain UNC-93 PF05978.16 KXS98878.1 - 5.8e-11 42.4 9.6 1.7e-10 40.8 9.6 1.8 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 KXS98878.1 - 9.3e-11 41.2 31.4 2.3e-10 39.9 31.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1345 PF07077.11 KXS98878.1 - 0.015 15.0 1.8 0.15 11.8 0.0 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1345) DUF4148 PF13663.6 KXS98878.1 - 0.045 13.9 0.1 0.15 12.3 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) GST_N_2 PF13409.6 KXS98879.1 - 4.5e-15 55.7 0.0 1.1e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXS98879.1 - 5.4e-07 29.5 0.0 1.3e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXS98879.1 - 0.00035 20.7 0.0 0.00076 19.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXS98879.1 - 0.0019 18.3 0.0 0.0041 17.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glyco_transf_22 PF03901.17 KXS98880.1 - 6.2e-36 124.5 14.5 8.5e-36 124.1 14.5 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family COX7a PF02238.15 KXS98880.1 - 3.1 8.3 9.5 2.6 8.5 2.2 3.9 3 1 0 3 3 3 0 Cytochrome c oxidase subunit VII Na_Ca_ex PF01699.24 KXS98881.1 - 1e-39 135.9 32.9 4.2e-22 78.7 8.7 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF4282 PF14110.6 KXS98881.1 - 0.26 12.1 0.0 0.26 12.1 0.0 3.9 2 2 2 4 4 4 0 Domain of unknown function (DUF4282) Hist_deacetyl PF00850.19 KXS98882.1 - 1.6e-55 188.8 1.1 3.6e-55 187.6 1.1 1.6 1 1 0 1 1 1 1 Histone deacetylase domain DUF2046 PF09755.9 KXS98883.1 - 0.00038 19.8 1.9 0.00038 19.8 1.9 2.2 3 0 0 3 3 3 1 Uncharacterized conserved protein H4 (DUF2046) FapA PF03961.13 KXS98883.1 - 0.046 12.3 0.9 0.086 11.4 0.9 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A HAUS-augmin3 PF14932.6 KXS98883.1 - 0.37 10.3 8.8 0.84 9.2 8.5 1.8 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 CCDC-167 PF15188.6 KXS98883.1 - 1.7 9.0 12.2 0.08 13.3 4.8 2.6 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF5305 PF17231.2 KXS98884.1 - 0.025 14.0 0.0 0.034 13.6 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) SID-1_RNA_chan PF13965.6 KXS98884.1 - 0.038 12.4 1.2 0.041 12.3 1.2 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 HATPase_c_3 PF13589.6 KXS98886.1 - 1.3e-11 44.5 0.1 2.6e-11 43.5 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.19 KXS98886.1 - 2.2e-08 33.8 0.0 1.1e-07 31.6 0.0 2.1 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.26 KXS98886.1 - 2.7e-08 34.3 0.1 5.6e-08 33.3 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase OPT PF03169.15 KXS98887.1 - 6.3e-172 573.4 59.2 7.3e-172 573.2 59.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Spt20 PF12090.8 KXS98888.1 - 1.2 8.7 10.5 0.042 13.5 1.6 2.2 2 0 0 2 2 2 0 Spt20 family Dsh_C PF12316.8 KXS98888.1 - 5.5 7.3 33.9 2.7 8.4 13.2 2.3 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal DEAD PF00270.29 KXS98902.1 - 2e-45 154.7 1.1 3.3e-45 154.0 1.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXS98902.1 - 7.6e-32 109.9 0.1 8.5e-31 106.6 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXS98902.1 - 3.6e-06 27.1 0.0 5.7e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KXS98902.1 - 0.00023 20.9 0.1 0.00049 19.9 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXS98902.1 - 0.00094 19.5 0.9 0.006 16.9 0.5 2.2 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KXS98902.1 - 0.012 15.9 0.6 0.062 13.6 0.6 2.2 1 1 0 1 1 1 0 AAA domain CMS1 PF14617.6 KXS98902.1 - 0.014 14.7 0.2 0.032 13.6 0.0 1.7 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit UvrD-helicase PF00580.21 KXS98902.1 - 0.069 12.7 0.1 0.22 11.0 0.1 1.4 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain fragilysinNterm PF16376.5 KXS98902.1 - 0.099 12.4 0.0 0.32 10.7 0.0 1.8 1 0 0 1 1 1 0 N-terminal domain of fragilysin Flavi_DEAD PF07652.14 KXS98902.1 - 0.13 12.2 0.1 0.69 9.9 0.1 2.2 1 1 0 1 1 1 0 Flavivirus DEAD domain Helicase_RecD PF05127.14 KXS98902.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Helicase Astacin PF01400.24 KXS98904.1 - 0.0044 16.6 1.7 0.016 14.8 1.1 2.1 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 KXS98904.1 - 0.0085 15.9 0.6 0.04 13.8 0.2 2.1 2 0 0 2 2 2 1 Matrixin Reprolysin_5 PF13688.6 KXS98904.1 - 0.093 12.9 0.4 0.14 12.3 0.4 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 KXS98904.1 - 0.099 12.3 0.1 0.14 11.7 0.1 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like p450 PF00067.22 KXS98905.1 - 8.2e-56 189.7 0.0 1.1e-55 189.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Inj_translocase PF16928.5 KXS98905.1 - 0.12 11.9 0.1 0.34 10.3 0.0 1.7 2 0 0 2 2 2 0 DNA/protein translocase of phage P22 injectosome DUF4175 PF13779.6 KXS98906.1 - 4.8 5.0 8.4 8 4.2 8.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Astacin PF01400.24 KXS98907.1 - 5.9e-06 26.0 3.3 2e-05 24.3 0.7 2.3 1 1 0 2 2 2 1 Astacin (Peptidase family M12A) Reprolysin_5 PF13688.6 KXS98907.1 - 0.00043 20.5 0.2 0.00062 20.0 0.2 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KXS98907.1 - 0.00089 19.8 0.0 0.0014 19.2 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KXS98907.1 - 0.0028 17.5 0.0 0.028 14.3 0.0 2.1 2 0 0 2 2 2 1 Matrixin Reprolysin_4 PF13583.6 KXS98907.1 - 0.0056 16.3 0.4 0.0085 15.8 0.4 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KXS98907.1 - 0.0077 16.1 0.4 0.014 15.3 0.4 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 KXS98907.1 - 0.05 13.5 0.0 0.076 12.9 0.0 1.2 1 0 0 1 1 1 0 Reprolysin (M12B) family zinc metalloprotease Peptidase_M66 PF10462.9 KXS98907.1 - 0.12 11.3 1.7 0.18 10.7 1.7 1.2 1 0 0 1 1 1 0 Peptidase M66 Phage_tail_X PF05489.12 KXS98907.1 - 0.17 11.6 0.2 0.36 10.5 0.2 1.5 1 0 0 1 1 1 0 Phage Tail Protein X Metallopep PF12044.8 KXS98907.1 - 0.24 10.0 0.0 0.3 9.6 0.0 1.1 1 0 0 1 1 1 0 Putative peptidase family Thiolase_N PF00108.23 KXS98909.1 - 2.6e-61 207.3 0.1 3.2e-61 207.0 0.1 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXS98909.1 - 2.1e-37 127.5 0.0 4e-37 126.6 0.0 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KXS98909.1 - 0.0095 15.5 1.2 0.02 14.5 0.5 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KXS98909.1 - 0.07 13.0 0.0 5.5 6.9 0.0 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Acyl_transf_3 PF01757.22 KXS98910.1 - 7.5e-30 104.1 30.0 1e-29 103.7 30.0 1.1 1 0 0 1 1 1 1 Acyltransferase family DUF563 PF04577.14 KXS98911.1 - 3.8e-29 102.3 0.0 5.9e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) NfrA_C PF13283.6 KXS98911.1 - 0.052 13.0 0.1 2.8 7.4 0.0 2.2 2 0 0 2 2 2 0 Bacteriophage N adsorption protein A C-term CFEM PF05730.11 KXS98912.1 - 3.5e-12 46.2 10.8 5.2e-12 45.7 10.8 1.2 1 0 0 1 1 1 1 CFEM domain adh_short PF00106.25 KXS98913.1 - 3e-19 69.2 0.0 4.6e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 KXS98913.1 - 1.5e-07 31.1 0.0 2.2e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.6 KXS98913.1 - 1.7e-07 31.0 0.0 3.4e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXS98913.1 - 2.6e-07 30.7 0.1 4.3e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXS98913.1 - 0.00034 19.9 0.0 0.00048 19.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein OAM_alpha PF16552.5 KXS98913.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 D-ornithine 4,5-aminomutase alpha-subunit DUF3431 PF11913.8 KXS98914.1 - 7.2e-69 231.8 0.0 9.4e-69 231.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Cupin_8 PF13621.6 KXS98915.1 - 8.5e-16 58.4 0.0 1.9e-14 54.0 0.0 2.2 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 KXS98915.1 - 1.4e-09 38.4 0.0 6e-08 33.1 0.0 2.8 2 1 0 2 2 2 1 JmjC domain, hydroxylase F-box-like PF12937.7 KXS98915.1 - 1.3e-06 28.1 0.1 3.3e-06 26.9 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS98915.1 - 0.00051 19.9 0.0 0.0016 18.3 0.0 1.9 1 0 0 1 1 1 1 F-box domain FAM212 PF15342.6 KXS98915.1 - 0.049 13.4 0.1 6.7 6.6 0.0 2.6 2 0 0 2 2 2 0 FAM212 family Cupin_1 PF00190.22 KXS98915.1 - 0.053 13.1 0.0 0.091 12.4 0.0 1.3 1 0 0 1 1 1 0 Cupin RPAP2_Rtr1 PF04181.13 KXS98916.1 - 7.3e-14 51.9 0.4 3.4e-13 49.7 0.4 2.2 1 1 0 1 1 1 1 Rtr1/RPAP2 family Glyco_transf_90 PF05686.12 KXS98918.1 - 6.8e-22 77.9 1.0 1.1e-21 77.2 1.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 KXS98918.1 - 0.00029 21.2 0.0 0.0011 19.3 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 WLM PF08325.10 KXS98919.1 - 1.5e-55 188.3 0.1 3.4e-55 187.1 0.1 1.6 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.18 KXS98919.1 - 0.0031 16.8 2.7 0.0031 16.8 2.7 2.9 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others Vps36-NZF-N PF16988.5 KXS98919.1 - 0.13 11.7 6.2 0.77 9.2 6.2 2.3 1 1 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Gly_transf_sug PF04488.15 KXS98920.1 - 6.6e-06 26.7 0.2 2.7e-05 24.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Ribosomal_S13_N PF08069.12 KXS98921.1 - 7.1e-30 102.8 0.1 1.2e-29 102.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 KXS98921.1 - 3.4e-15 56.0 0.2 5.1e-15 55.4 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 KXS98921.1 - 0.01 15.8 0.1 0.021 14.7 0.0 1.6 2 0 0 2 2 2 0 'Paired box' domain LIP PF03583.14 KXS98922.1 - 2.7e-62 210.7 0.3 3.8e-62 210.2 0.3 1.1 1 0 0 1 1 1 1 Secretory lipase DUF3863 PF12979.7 KXS98922.1 - 0.012 14.5 0.0 0.019 13.9 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3863) NDT80_PhoG PF05224.12 KXS98923.1 - 9.6e-38 130.3 0.5 2.4e-37 128.9 0.5 1.7 1 1 0 1 1 1 1 NDT80 / PhoG like DNA-binding family NPM1-C PF16276.5 KXS98923.1 - 0.097 12.7 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Nucleophosmin C-terminal domain NDT80_PhoG PF05224.12 KXS98924.1 - 9.6e-38 130.3 0.5 2.4e-37 128.9 0.5 1.7 1 1 0 1 1 1 1 NDT80 / PhoG like DNA-binding family NPM1-C PF16276.5 KXS98924.1 - 0.097 12.7 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Nucleophosmin C-terminal domain SRPRB PF09439.10 KXS98925.1 - 6.5e-35 120.2 0.0 3.5e-34 117.8 0.0 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KXS98925.1 - 1.7e-07 31.3 0.0 2.8e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KXS98925.1 - 2.6e-06 27.0 0.0 3e-05 23.5 0.0 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_16 PF13191.6 KXS98925.1 - 0.00027 21.4 0.3 0.00046 20.6 0.3 1.6 1 1 0 1 1 1 1 AAA ATPase domain Roc PF08477.13 KXS98925.1 - 0.0019 18.4 0.0 0.0055 16.9 0.0 1.9 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 KXS98925.1 - 0.0029 17.0 0.0 0.006 16.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein Septin PF00735.18 KXS98925.1 - 0.0033 16.7 0.0 0.01 15.2 0.0 1.6 2 0 0 2 2 2 1 Septin AAA_29 PF13555.6 KXS98925.1 - 0.0043 16.8 0.1 0.0089 15.7 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 KXS98925.1 - 0.0044 16.8 0.1 0.68 9.7 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 KXS98925.1 - 0.0046 16.5 0.0 0.015 14.8 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 KXS98925.1 - 0.013 16.0 0.1 0.018 15.6 0.1 1.5 1 1 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 KXS98925.1 - 0.02 14.8 0.2 0.15 12.0 0.0 2.3 3 0 0 3 3 3 0 RsgA GTPase AAA_22 PF13401.6 KXS98925.1 - 0.021 15.1 0.0 0.037 14.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KXS98925.1 - 0.022 15.2 0.2 0.081 13.3 0.2 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KXS98925.1 - 0.023 15.2 0.0 0.039 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.12 KXS98925.1 - 0.026 13.9 0.0 0.053 12.9 0.0 1.5 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_5 PF07728.14 KXS98925.1 - 0.041 13.9 0.0 0.08 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.6 KXS98925.1 - 0.052 13.3 0.0 0.073 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Ras PF00071.22 KXS98925.1 - 0.054 13.1 0.0 0.2 11.2 0.0 1.8 1 1 0 1 1 1 0 Ras family RuvB_N PF05496.12 KXS98925.1 - 0.1 12.3 0.0 0.31 10.8 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain cobW PF02492.19 KXS98925.1 - 0.17 11.4 0.7 2.6 7.6 0.3 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SH3_1 PF00018.28 KXS98926.1 - 5.8e-10 38.6 0.1 1.3e-09 37.5 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXS98926.1 - 2.2e-07 30.6 0.3 5.6e-07 29.3 0.2 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KXS98926.1 - 0.00014 21.5 0.0 0.00027 20.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain CHAP PF05257.16 KXS98926.1 - 0.17 12.5 0.0 0.37 11.4 0.0 1.6 1 0 0 1 1 1 0 CHAP domain Peptidase_S10 PF00450.22 KXS98927.1 - 2.4e-12 47.0 0.1 3e-12 46.7 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase SH3_1 PF00018.28 KXS98928.1 - 5.8e-10 38.6 0.1 1.3e-09 37.5 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXS98928.1 - 2.2e-07 30.6 0.3 5.6e-07 29.3 0.2 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KXS98928.1 - 0.00014 21.5 0.0 0.00027 20.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain CHAP PF05257.16 KXS98928.1 - 0.17 12.5 0.0 0.37 11.4 0.0 1.6 1 0 0 1 1 1 0 CHAP domain TPT PF03151.16 KXS98929.1 - 6.5e-39 134.0 20.9 8.2e-39 133.7 20.9 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KXS98929.1 - 8.2e-13 48.2 21.9 1e-12 47.9 21.9 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KXS98929.1 - 0.4 10.9 28.8 0.06 13.5 14.2 2.5 2 1 0 2 2 2 0 EamA-like transporter family Acyl_transf_3 PF01757.22 KXS98931.1 - 9.4e-32 110.4 22.9 1.3e-31 109.9 22.9 1.2 1 0 0 1 1 1 1 Acyltransferase family Glyco_transf_25 PF01755.17 KXS98932.1 - 0.00077 19.4 0.0 0.0014 18.5 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Atg14 PF10186.9 KXS98933.1 - 4.5e-54 183.7 1.3 5.9e-54 183.3 1.3 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 OEP PF02321.18 KXS98933.1 - 0.011 15.6 1.1 0.02 14.7 1.1 1.4 1 0 0 1 1 1 0 Outer membrane efflux protein Spc7 PF08317.11 KXS98933.1 - 0.078 11.8 6.3 0.13 11.1 6.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein FAM76 PF16046.5 KXS98933.1 - 0.082 12.2 1.9 0.18 11.1 1.9 1.6 1 0 0 1 1 1 0 FAM76 protein YkyA PF10368.9 KXS98933.1 - 0.088 12.5 4.8 0.16 11.6 4.8 1.4 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein DUF4140 PF13600.6 KXS98933.1 - 0.17 12.3 3.7 0.31 11.5 3.0 1.8 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) RasGAP_C PF03836.15 KXS98933.1 - 0.29 11.3 3.2 0.56 10.4 3.2 1.4 1 0 0 1 1 1 0 RasGAP C-terminus TMPIT PF07851.13 KXS98933.1 - 1.1 8.4 3.2 1.7 7.8 3.2 1.3 1 0 0 1 1 1 0 TMPIT-like protein FYVE_2 PF02318.16 KXS98933.1 - 8.3 6.7 6.9 1.2 9.4 1.4 2.5 3 0 0 3 3 3 0 FYVE-type zinc finger Ecm33 PF12454.8 KXS98934.1 - 0.0023 18.0 0.1 0.0023 18.0 0.1 2.4 2 1 0 2 2 2 1 GPI-anchored cell wall organization protein PX PF00787.24 KXS98936.1 - 1.6e-20 73.2 1.3 5.5e-20 71.5 0.3 2.3 2 1 0 2 2 2 1 PX domain Vps5 PF09325.10 KXS98936.1 - 2.2e-11 43.8 10.5 1.1e-05 25.1 0.3 2.2 1 1 1 2 2 2 2 Vps5 C terminal like BAR PF03114.18 KXS98936.1 - 0.00043 20.0 7.3 0.005 16.5 7.3 2.2 1 1 0 1 1 1 1 BAR domain Sec34 PF04136.15 KXS98936.1 - 0.037 13.9 0.4 0.21 11.5 0.0 2.3 2 2 1 3 3 3 0 Sec34-like family BAR_3 PF16746.5 KXS98936.1 - 0.17 11.5 2.1 0.43 10.2 0.1 2.1 2 0 0 2 2 2 0 BAR domain of APPL family APG6_N PF17675.1 KXS98936.1 - 0.54 10.8 8.9 32 5.1 0.0 2.9 1 1 1 2 2 2 0 Apg6 coiled-coil region TerB PF05099.13 KXS98936.1 - 1.2 9.1 7.5 1.8 8.5 2.7 2.6 2 0 0 2 2 2 0 Tellurite resistance protein TerB Ribosomal_60s PF00428.19 KXS98938.1 - 6 7.5 9.0 4.4 8.0 7.1 1.8 1 1 1 2 2 2 0 60s Acidic ribosomal protein DUF4519 PF15012.6 KXS98938.1 - 8.5 6.6 8.3 20 5.4 8.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) NARP1 PF12569.8 KXS98938.1 - 9 5.1 7.3 13 4.5 7.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Lipase_GDSL_2 PF13472.6 KXS98939.1 - 4.6e-12 46.7 1.9 1.8e-11 44.8 1.9 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXS98939.1 - 2.2e-09 37.6 0.1 5.7e-09 36.2 0.1 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PAP2_3 PF14378.6 KXS98952.1 - 1.5e-23 83.4 23.7 8e-20 71.3 7.1 2.5 3 0 0 3 3 3 2 PAP2 superfamily PAP2 PF01569.21 KXS98952.1 - 0.013 15.2 2.7 0.013 15.2 2.7 2.1 1 1 1 2 2 2 0 PAP2 superfamily PAP2_C PF14360.6 KXS98952.1 - 0.023 15.2 0.8 0.023 15.2 0.8 3.8 5 0 0 5 5 5 0 PAP2 superfamily C-terminal DUF1129 PF06570.11 KXS98952.1 - 3.7 7.0 5.2 0.48 9.9 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) ADK PF00406.22 KXS98954.1 - 7.8e-36 123.5 0.0 1e-19 71.1 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.14 KXS98954.1 - 1.5e-16 60.0 0.0 2.5e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.6 KXS98954.1 - 3.3e-13 50.2 0.0 3.4e-09 37.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KXS98954.1 - 2.2e-07 31.5 0.0 2.1e-06 28.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KXS98954.1 - 0.0022 18.1 0.0 0.046 13.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KXS98954.1 - 0.11 12.8 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KXS98954.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 KXS98954.1 - 0.12 12.6 0.0 0.25 11.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain Rad51 PF08423.11 KXS98955.1 - 1.1e-09 38.0 0.0 1.6e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 KXS98955.1 - 2.2e-06 27.3 0.1 3.9e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein IstB_IS21 PF01695.17 KXS98955.1 - 0.0007 19.4 0.0 0.0016 18.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein ATPase PF06745.13 KXS98955.1 - 0.0011 18.4 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 KaiC AAA_24 PF13479.6 KXS98955.1 - 0.002 17.9 0.0 0.0034 17.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 KXS98955.1 - 0.012 15.1 0.1 0.019 14.4 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_16 PF13191.6 KXS98955.1 - 0.012 16.0 0.0 0.034 14.5 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 KXS98955.1 - 0.014 15.4 0.1 0.029 14.3 0.1 1.5 1 1 0 1 1 1 0 NACHT domain SSXRD PF09514.10 KXS98955.1 - 0.018 14.6 0.5 0.035 13.7 0.5 1.4 1 0 0 1 1 1 0 SSXRD motif RNA12 PF10443.9 KXS98955.1 - 0.077 11.7 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 RNA12 protein AAA_25 PF13481.6 KXS98955.1 - 0.25 10.9 2.2 0.27 10.8 0.1 2.0 3 0 0 3 3 3 0 AAA domain DUF1757 PF08560.10 KXS98956.1 - 0.00038 20.5 0.0 0.00054 20.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1757) ORC4_C PF14629.6 KXS98957.1 - 4.9e-46 156.8 0.0 9.6e-46 155.9 0.0 1.5 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 KXS98957.1 - 6e-15 56.0 0.4 6e-15 56.0 0.4 3.0 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 KXS98957.1 - 6.2e-07 29.8 0.1 2.6e-06 27.7 0.1 2.1 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KXS98957.1 - 1.4e-06 28.8 0.7 4.9e-06 27.0 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 KXS98957.1 - 2.2e-05 23.7 0.0 4.2e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) NACHT PF05729.12 KXS98957.1 - 5.9e-05 23.1 0.4 0.00023 21.1 0.4 2.0 1 1 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 KXS98957.1 - 0.0022 17.2 0.1 0.0053 16.0 0.1 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA_14 PF13173.6 KXS98957.1 - 0.0042 17.1 0.0 0.021 14.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KXS98957.1 - 0.0048 16.6 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_7 PF12775.7 KXS98957.1 - 0.016 14.7 0.3 0.046 13.2 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region ATPase_2 PF01637.18 KXS98957.1 - 0.029 14.3 0.0 0.029 14.3 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NOA36 PF06524.12 KXS98957.1 - 0.041 13.2 13.5 0.083 12.2 13.5 1.4 1 0 0 1 1 1 0 NOA36 protein AAA_19 PF13245.6 KXS98957.1 - 0.07 13.5 0.2 0.27 11.5 0.2 2.0 1 1 0 1 1 1 0 AAA domain Roc PF08477.13 KXS98957.1 - 0.13 12.5 0.0 0.42 10.8 0.0 1.9 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Sugar_tr PF00083.24 KXS98958.1 - 2.3e-123 412.4 23.7 2.7e-123 412.2 23.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS98958.1 - 1.4e-19 70.2 32.5 1.4e-19 70.2 32.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Ilm1 PF10311.9 KXS98958.1 - 0.11 12.1 1.2 0.22 11.1 1.2 1.5 1 0 0 1 1 1 0 Increased loss of mitochondrial DNA protein 1 LPD25 PF18840.1 KXS98959.1 - 0.061 13.9 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 Large polyvalent protein associated domain 25 DUF3113 PF11310.8 KXS98960.1 - 0.033 14.1 0.1 0.077 13.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3113) DUF5054 PF16477.5 KXS98961.1 - 0.025 14.4 0.3 0.038 13.8 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5054) zf-BED PF02892.15 KXS98961.1 - 0.046 13.7 0.6 0.091 12.8 0.6 1.4 1 0 0 1 1 1 0 BED zinc finger HalX PF08663.10 KXS98961.1 - 0.097 13.0 5.0 2.9 8.3 2.3 2.7 2 1 0 2 2 2 0 HalX domain UBA2_C PF16195.5 KXS98961.1 - 0.12 13.1 9.5 0.3 11.8 0.2 3.4 3 0 0 3 3 3 0 SUMO-activating enzyme subunit 2 C-terminus PilJ PF13675.6 KXS98961.1 - 0.14 12.1 3.6 0.34 10.9 3.4 1.8 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term TMPIT PF07851.13 KXS98961.1 - 0.18 11.1 0.2 0.25 10.6 0.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein SMC_N PF02463.19 KXS98962.1 - 6.6e-65 218.6 0.1 2.5e-64 216.7 0.1 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KXS98962.1 - 1.1e-20 74.1 0.1 5.7e-20 71.8 0.0 2.4 2 0 0 2 2 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KXS98962.1 - 1.3e-10 41.6 5.0 8e-05 22.6 0.2 3.0 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXS98962.1 - 0.00048 19.8 0.0 0.0011 18.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KXS98962.1 - 0.0006 20.4 49.0 0.0006 20.4 49.0 7.6 3 2 1 4 4 2 1 AAA domain Spc7 PF08317.11 KXS98962.1 - 0.0025 16.8 14.6 0.0025 16.8 14.6 7.5 2 2 6 8 8 8 2 Spc7 kinetochore protein FlxA PF14282.6 KXS98962.1 - 0.0026 17.7 5.6 0.0026 17.7 5.6 8.6 4 2 4 9 9 6 1 FlxA-like protein TMF_DNA_bd PF12329.8 KXS98962.1 - 0.003 17.5 7.9 0.003 17.5 7.9 12.0 6 4 6 12 12 12 1 TATA element modulatory factor 1 DNA binding HIP1_clath_bdg PF16515.5 KXS98962.1 - 0.0047 17.5 12.2 0.0047 17.5 12.2 9.8 3 2 5 9 9 7 1 Clathrin-binding domain of Huntingtin-interacting protein 1 UPF0242 PF06785.11 KXS98962.1 - 0.0064 16.6 22.4 0.0064 16.6 22.4 6.5 3 2 2 5 5 4 1 Uncharacterised protein family (UPF0242) N-terminus Cnn_1N PF07989.11 KXS98962.1 - 0.0069 16.5 4.5 0.0069 16.5 4.5 10.6 6 5 1 7 7 4 1 Centrosomin N-terminal motif 1 NRN1 PF15056.6 KXS98962.1 - 0.086 12.9 1.7 0.48 10.5 0.1 3.1 2 1 0 2 2 2 0 Neuritin protein family DUF2999 PF11212.8 KXS98962.1 - 0.097 13.0 0.1 0.097 13.0 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2999) Sas10 PF09368.10 KXS98962.1 - 6 7.4 10.8 0.21 12.1 0.9 3.5 3 0 0 3 3 3 0 Sas10 C-terminal domain DUF3896 PF13035.6 KXS98962.1 - 6.6 7.0 11.3 0.16 12.1 0.9 3.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) Peptidase_M24 PF00557.24 KXS98963.1 - 4.1e-56 190.0 0.1 5.5e-56 189.6 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KXS98963.1 - 1.1e-24 86.4 0.0 2.1e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Creatinase_N PF01321.18 KXS98963.1 - 0.15 12.7 0.0 0.41 11.3 0.0 1.7 1 1 0 1 1 1 0 Creatinase/Prolidase N-terminal domain LacAB_rpiB PF02502.18 KXS98965.1 - 3.6e-44 150.1 0.1 4.2e-44 149.9 0.1 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Gly_rich_SFCGS PF14272.6 KXS98965.1 - 0.0023 17.9 0.3 0.091 12.8 0.0 2.7 2 1 0 3 3 3 1 Glycine-rich SFCGS DUF2620 PF10941.8 KXS98965.1 - 0.047 13.8 1.1 0.11 12.6 0.5 2.0 2 1 0 2 2 2 0 Protein of unknown function DUF2620 Mit_ribos_Mrp51 PF11709.8 KXS98966.1 - 4.7e-106 355.5 0.4 5.6e-106 355.2 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit ATP_synt_H PF05493.13 KXS98967.1 - 9.6e-10 38.8 1.3 0.00033 21.1 0.1 2.1 1 1 1 2 2 2 2 ATP synthase subunit H NAT PF04768.13 KXS98970.1 - 2.4e-52 177.0 0.0 8.6e-51 172.0 0.0 2.9 3 0 0 3 3 3 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase TPR_12 PF13424.6 KXS98970.1 - 2.9e-12 46.7 4.4 2e-09 37.6 0.8 3.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 KXS98970.1 - 7.2e-06 25.7 4.5 0.012 15.5 0.2 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat AAA_16 PF13191.6 KXS98970.1 - 6e-05 23.5 1.1 0.00076 19.9 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain TPR_19 PF14559.6 KXS98970.1 - 0.00024 21.5 2.4 2.1 8.9 0.2 4.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXS98970.1 - 0.0011 19.6 16.6 5.7 8.0 0.0 7.1 6 2 2 8 8 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXS98970.1 - 0.04 14.0 0.6 25 5.3 0.2 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_22 PF13401.6 KXS98970.1 - 0.069 13.4 0.0 5.9 7.2 0.0 3.0 2 0 0 2 2 2 0 AAA domain TPR_6 PF13174.6 KXS98970.1 - 0.096 13.4 0.3 16 6.4 0.0 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXS98970.1 - 0.12 12.6 0.6 54 4.4 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 KXS98970.1 - 0.67 10.7 15.0 3.6 8.5 0.1 6.0 6 0 0 6 6 5 0 Tetratricopeptide repeat Arv1 PF04161.13 KXS98971.1 - 4.2e-75 252.5 0.0 4.9e-75 252.3 0.0 1.0 1 0 0 1 1 1 1 Arv1-like family FAM76 PF16046.5 KXS98971.1 - 0.36 10.2 0.5 0.49 9.7 0.5 1.1 1 0 0 1 1 1 0 FAM76 protein Bac_luciferase PF00296.20 KXS98972.1 - 8.1e-66 222.6 0.1 9.7e-66 222.3 0.1 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase Pro_isomerase PF00160.21 KXS98976.1 - 2.9e-43 147.9 0.0 4.6e-43 147.2 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD LETM1 PF07766.13 KXS98977.1 - 1.5e-104 349.1 0.2 1.5e-104 349.1 0.2 2.0 2 0 0 2 2 2 1 LETM1-like protein SAP PF02037.27 KXS98977.1 - 0.00024 20.7 0.0 0.0025 17.5 0.0 2.5 2 0 0 2 2 2 1 SAP domain Caudo_TAP PF02413.17 KXS98977.1 - 0.019 15.1 1.6 0.019 15.1 1.6 2.7 2 1 0 2 2 2 0 Caudovirales tail fibre assembly protein, lambda gpK PAN_1 PF00024.26 KXS98979.1 - 0.0025 17.8 0.8 0.0067 16.4 0.8 1.7 1 0 0 1 1 1 1 PAN domain SCAB_CC PF16712.5 KXS98979.1 - 0.019 14.8 1.5 0.041 13.7 1.5 1.5 1 0 0 1 1 1 0 Coiled-coil regions of plant-specific actin-binding protein RbpA PF13397.6 KXS98979.1 - 0.11 13.2 0.1 0.78 10.4 0.0 2.4 2 0 0 2 2 2 0 RNA polymerase-binding protein DUF3844 PF12955.7 KXS98980.1 - 5.1e-37 126.2 4.1 9e-37 125.4 4.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) SAM_LFY PF01698.16 KXS98980.1 - 0.11 12.4 0.0 0.36 10.8 0.0 1.8 2 0 0 2 2 2 0 Floricaula / Leafy protein SAM domain ACBP PF00887.19 KXS98981.1 - 3.9e-18 65.4 4.8 8.1e-18 64.4 4.8 1.6 1 0 0 1 1 1 1 Acyl CoA binding protein CorA PF01544.18 KXS98981.1 - 0.00093 18.6 0.0 0.0022 17.4 0.0 1.6 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein MFS_1 PF07690.16 KXS98982.1 - 1.2e-27 96.8 26.4 1.2e-27 96.8 26.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Tmemb_18A PF09771.9 KXS98982.1 - 0.078 13.4 0.1 5.9 7.3 0.0 2.8 3 0 0 3 3 3 0 Transmembrane protein 188 CDP-OH_P_transf PF01066.21 KXS98983.1 - 1.9e-13 51.0 0.0 1.9e-13 51.0 0.0 3.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase CDP-OH_P_transf PF01066.21 KXS98984.1 - 1.8e-13 51.1 0.0 1.8e-13 51.1 0.0 3.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF4118 PF13493.6 KXS98984.1 - 9.2 6.1 10.0 0.47 10.3 0.7 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4118) Na_H_Exchanger PF00999.21 KXS98986.1 - 1.7e-35 122.6 19.8 2e-35 122.3 19.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF4271 PF14093.6 KXS98986.1 - 9 6.1 10.8 70 3.2 11.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4271) Rpn3_C PF08375.11 KXS98987.1 - 2.4e-21 75.9 1.2 5.3e-21 74.8 1.2 1.6 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 KXS98987.1 - 1.9e-20 73.4 0.3 6e-20 71.7 0.1 2.0 2 0 0 2 2 2 1 PCI domain FA_desaturase PF00487.24 KXS98988.1 - 4.4e-26 92.3 26.4 6.3e-26 91.7 26.4 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KXS98988.1 - 1.3e-12 47.6 0.0 5.5e-12 45.7 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain bacHORMA_2 PF18173.1 KXS98989.1 - 0.039 13.8 0.0 0.047 13.5 0.0 1.1 1 0 0 1 1 1 0 Bacterial HORMA domain 2 PALP PF00291.25 KXS98991.1 - 9.1e-53 179.6 0.9 1.1e-52 179.3 0.9 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Clr5 PF14420.6 KXS98991.1 - 0.075 13.3 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Clr5 domain Rho_N PF07498.12 KXS98991.1 - 0.14 12.1 0.0 0.62 10.0 0.0 2.0 2 0 0 2 2 2 0 Rho termination factor, N-terminal domain APH PF01636.23 KXS98992.1 - 1.3e-12 48.1 0.0 1.6e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXS98992.1 - 0.00023 20.8 0.0 0.00036 20.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase PLA2_B PF01735.18 KXS98992.1 - 0.0095 14.4 0.0 0.015 13.7 0.0 1.2 1 0 0 1 1 1 1 Lysophospholipase catalytic domain PTS_EIIC_2 PF13303.6 KXS98993.1 - 0.013 14.5 0.6 0.022 13.8 0.6 1.3 1 0 0 1 1 1 0 Phosphotransferase system, EIIC Mg_trans_NIPA PF05653.14 KXS98994.1 - 1.6e-89 299.9 29.3 2.1e-89 299.5 29.3 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KXS98994.1 - 4.5e-07 30.1 8.9 4.5e-07 30.1 8.9 3.2 3 0 0 3 3 3 2 EamA-like transporter family Abhydrolase_2 PF02230.16 KXS98995.1 - 2.4e-35 122.3 0.0 3.6e-35 121.8 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 KXS98995.1 - 0.00023 20.9 0.0 0.00063 19.5 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 KXS98995.1 - 0.0012 18.1 0.3 0.36 10.0 0.1 3.0 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXS98995.1 - 0.0074 16.9 0.0 0.01 16.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KXS98995.1 - 0.013 15.0 0.0 0.3 10.5 0.0 2.5 3 0 0 3 3 3 0 Prolyl oligopeptidase family DLH PF01738.18 KXS98995.1 - 0.18 11.3 0.0 0.48 9.9 0.0 1.8 2 1 0 2 2 2 0 Dienelactone hydrolase family CN_hydrolase PF00795.22 KXS98996.1 - 5.5e-38 130.8 0.0 7.3e-38 130.4 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF3450 PF11932.8 KXS98997.1 - 0.028 13.7 0.9 0.035 13.4 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Med11 PF10280.9 KXS98997.1 - 0.15 12.5 2.2 1.7 9.1 0.0 2.1 1 1 1 2 2 2 0 Mediator complex protein MFS_MOT1 PF16983.5 KXS98998.1 - 0.059 13.8 1.8 0.12 12.7 1.8 1.5 1 0 0 1 1 1 0 Molybdate transporter of MFS superfamily COG4 PF08318.12 KXS98999.1 - 6.8e-122 406.7 0.0 1e-121 406.2 0.0 1.3 1 0 0 1 1 1 1 COG4 transport protein FGGY_C PF02782.16 KXS98999.1 - 0.061 13.1 0.2 0.13 11.9 0.2 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Nsp1_C PF05064.13 KXS98999.1 - 0.064 13.1 0.7 1 9.2 0.1 2.6 1 1 1 2 2 2 0 Nsp1-like C-terminal region HEM4 PF02602.15 KXS99000.1 - 1.1e-38 132.9 0.0 7.2e-38 130.2 0.0 1.9 1 1 0 1 1 1 1 Uroporphyrinogen-III synthase HemD ThiF PF00899.21 KXS99001.1 - 2.4e-56 190.8 0.0 3.6e-56 190.2 0.0 1.2 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 KXS99001.1 - 4.8e-08 33.5 0.1 1.8e-07 31.7 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain FliJ PF02050.16 KXS99001.1 - 0.046 14.0 1.5 0.086 13.1 1.5 1.3 1 0 0 1 1 1 0 Flagellar FliJ protein NAD_binding_7 PF13241.6 KXS99001.1 - 0.096 13.1 0.0 0.26 11.7 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding TMF_DNA_bd PF12329.8 KXS99001.1 - 0.21 11.6 2.2 0.59 10.2 2.2 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding RIC3 PF15361.6 KXS99001.1 - 0.32 11.4 1.1 0.71 10.3 1.1 1.5 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 FlxA PF14282.6 KXS99001.1 - 0.33 11.0 7.8 0.67 10.0 7.8 1.5 1 0 0 1 1 1 0 FlxA-like protein PspA_IM30 PF04012.12 KXS99001.1 - 1.3 8.6 6.1 2.3 7.7 6.1 1.4 1 0 0 1 1 1 0 PspA/IM30 family SlyX PF04102.12 KXS99001.1 - 2 9.1 5.6 5.5 7.7 5.6 1.7 1 0 0 1 1 1 0 SlyX ABA_WDS PF02496.16 KXS99002.1 - 0.0013 19.2 2.6 0.0013 19.2 2.6 2.1 2 1 0 2 2 2 1 ABA/WDS induced protein YtxH PF12732.7 KXS99002.1 - 0.0054 17.2 2.4 0.1 13.1 2.4 2.7 1 1 0 1 1 1 1 YtxH-like protein DUF3042 PF11240.8 KXS99002.1 - 0.014 15.4 0.2 0.03 14.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) zf-C2H2_4 PF13894.6 KXS99003.1 - 1.2e-05 25.7 2.1 0.0075 17.0 0.2 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXS99003.1 - 2.3e-05 24.6 5.8 0.01 16.3 2.2 2.6 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KXS99003.1 - 0.0043 17.4 5.7 0.066 13.7 2.5 2.9 3 0 0 3 3 3 1 Zinc finger, C2H2 type Hydantoinase_B PF02538.14 KXS99004.1 - 1.4e-222 739.7 0.3 2e-222 739.2 0.3 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KXS99004.1 - 2e-102 342.4 0.3 4.5e-102 341.2 0.3 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KXS99004.1 - 2.7e-62 209.6 0.9 1.3e-60 204.1 0.0 2.7 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region DASH_Spc34 PF08657.10 KXS99006.1 - 6.6e-39 134.2 2.1 2.4e-20 73.4 0.1 2.0 1 1 1 2 2 2 2 DASH complex subunit Spc34 DASH_Spc19 PF08287.11 KXS99006.1 - 0.0047 16.8 0.6 0.0079 16.1 0.6 1.3 1 0 0 1 1 1 1 Spc19 DUF724 PF05266.14 KXS99006.1 - 0.12 12.2 0.1 0.19 11.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ABC_tran_CTD PF16326.5 KXS99006.1 - 5.2 7.4 7.6 2.4 8.5 2.0 2.4 2 0 0 2 2 2 0 ABC transporter C-terminal domain Lycopene_cycl PF05834.12 KXS99007.1 - 0.0015 17.7 0.0 0.0016 17.5 0.0 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KXS99007.1 - 0.0015 18.7 0.0 0.002 18.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXS99007.1 - 0.0087 15.7 0.0 0.0087 15.7 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXS99007.1 - 0.047 12.9 0.1 0.058 12.6 0.1 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase IlvN PF07991.12 KXS99007.1 - 0.071 12.7 0.2 0.2 11.2 0.2 1.8 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain FAD_binding_3 PF01494.19 KXS99007.1 - 0.096 11.9 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KXS99007.1 - 0.13 10.9 0.1 0.15 10.7 0.1 1.1 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.24 KXS99007.1 - 0.16 11.0 0.0 0.16 11.0 0.0 1.0 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 KXS99007.1 - 0.16 11.1 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pox_RNA_Pol_22 PF05273.13 KXS99008.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Poxvirus RNA polymerase 22 kDa subunit MAD PF05557.13 KXS99012.1 - 8e-56 189.7 80.5 2.1e-55 188.4 80.5 1.6 1 1 0 1 1 1 1 Mitotic checkpoint protein WD40_alt PF14077.6 KXS99012.1 - 9.6 6.2 10.0 12 5.8 0.2 4.9 3 1 1 4 4 4 0 Alternative WD40 repeat motif ABC_ATPase PF09818.9 KXS99013.1 - 7.8e-162 539.1 0.0 9.7e-162 538.8 0.0 1.1 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_23 PF13476.6 KXS99013.1 - 0.00041 20.9 0.7 0.00076 20.0 0.1 1.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KXS99013.1 - 0.037 13.8 0.1 0.078 12.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Myb_DNA-binding PF00249.31 KXS99014.1 - 5.6e-19 68.1 0.6 1.1e-09 38.3 0.0 3.5 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXS99014.1 - 4.6e-13 49.2 1.1 1.3e-07 31.7 0.1 3.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KXS99014.1 - 0.046 14.1 5.8 0.52 10.7 0.0 3.8 4 0 0 4 4 4 0 Myb/SANT-like DNA-binding domain Rap1_C PF11626.8 KXS99014.1 - 1.2 9.3 3.9 0.63 10.2 0.2 2.5 2 1 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain 6PGD PF00393.19 KXS99015.1 - 4e-127 423.5 0.0 6.1e-127 422.9 0.0 1.3 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KXS99015.1 - 4.8e-48 163.3 0.1 9.7e-48 162.3 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KXS99015.1 - 0.0091 16.2 0.5 0.051 13.8 0.0 2.2 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Evr1_Alr PF04777.13 KXS99016.1 - 2.2e-30 105.1 3.5 2.2e-30 105.1 3.5 1.7 2 0 0 2 2 2 1 Erv1 / Alr family NPR2 PF06218.11 KXS99017.1 - 0.095 11.4 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Nitrogen permease regulator 2 PCI PF01399.27 KXS99017.1 - 0.097 13.2 0.0 0.36 11.4 0.0 1.9 1 0 0 1 1 1 0 PCI domain SHMT PF00464.19 KXS99018.1 - 4.9e-199 660.9 0.0 5.8e-199 660.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase HsbA PF12296.8 KXS99019.1 - 4.5e-27 94.9 9.1 4.5e-27 94.9 9.1 2.4 3 0 0 3 3 3 1 Hydrophobic surface binding protein A Baculo_PEP_C PF04513.12 KXS99019.1 - 0.076 13.1 0.6 0.25 11.4 0.4 1.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus LPP PF04728.13 KXS99019.1 - 0.36 11.3 2.7 1.4 9.3 0.7 2.7 2 1 0 2 2 2 0 Lipoprotein leucine-zipper Vac7 PF12751.7 KXS99021.1 - 3e-147 491.0 5.4 3e-147 491.0 5.4 2.5 3 0 0 3 3 3 1 Vacuolar segregation subunit 7 SURF6 PF04935.12 KXS99023.1 - 8.8e-50 169.3 47.7 8.8e-50 169.3 47.7 4.9 2 1 2 4 4 4 1 Surfeit locus protein 6 RRP14 PF15459.6 KXS99023.1 - 9.3e-13 48.6 2.2 9.3e-13 48.6 2.2 7.7 6 2 1 7 7 7 1 60S ribosome biogenesis protein Rrp14 SURF6 PF04935.12 KXS99024.1 - 8.3e-50 169.4 47.7 8.3e-50 169.4 47.7 4.7 2 1 1 4 4 4 1 Surfeit locus protein 6 RRP14 PF15459.6 KXS99024.1 - 8.9e-13 48.6 2.2 8.9e-13 48.6 2.2 7.7 6 2 1 7 7 7 1 60S ribosome biogenesis protein Rrp14 Aminotran_4 PF01063.19 KXS99025.1 - 1.2e-35 123.4 0.0 1.7e-35 122.9 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV Peptidase_M3 PF01432.20 KXS99028.1 - 2.4e-110 369.9 3.8 3.2e-110 369.5 3.8 1.2 1 0 0 1 1 1 1 Peptidase family M3 Asparaginase PF00710.20 KXS99028.1 - 0.11 12.1 0.1 0.22 11.1 0.1 1.4 1 0 0 1 1 1 0 Asparaginase, N-terminal DUF465 PF04325.13 KXS99028.1 - 3.6 7.7 5.8 5 7.2 3.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF465) SR-25 PF10500.9 KXS99029.1 - 0.0057 16.3 7.8 0.0057 16.3 7.8 2.2 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein YL1 PF05764.13 KXS99029.1 - 0.092 12.9 5.7 0.024 14.8 2.6 1.6 2 0 0 2 2 2 0 YL1 nuclear protein DUF3439 PF11921.8 KXS99030.1 - 0.37 10.8 4.7 0.41 10.6 4.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) HET PF06985.11 KXS99040.1 - 1.1e-33 116.6 0.6 2.4e-33 115.6 0.6 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DNA_ligase_A_N PF04675.14 KXS99041.1 - 7.2e-27 94.8 0.0 1.6e-26 93.7 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_M PF01068.21 KXS99041.1 - 2.5e-20 73.0 0.0 4.2e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain RNA_ligase PF09414.10 KXS99041.1 - 6.1e-05 23.4 0.0 0.00014 22.2 0.0 1.6 1 0 0 1 1 1 1 RNA ligase DUF3459 PF11941.8 KXS99041.1 - 0.0049 17.1 0.0 0.018 15.4 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3459) DUF3903 PF13043.6 KXS99041.1 - 0.0072 16.0 0.3 0.016 15.0 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3903) DNA_ligase_A_C PF04679.15 KXS99041.1 - 0.098 13.3 0.0 12 6.6 0.0 2.6 2 0 0 2 2 2 0 ATP dependent DNA ligase C terminal region HPP PF04982.13 KXS99042.1 - 4.3e-41 139.9 6.8 7.6e-41 139.1 6.8 1.4 1 0 0 1 1 1 1 HPP family FtsK_4TM PF13491.6 KXS99042.1 - 0.031 14.0 3.4 0.046 13.4 3.4 1.3 1 0 0 1 1 1 0 4TM region of DNA translocase FtsK/SpoIIIE DUF1375 PF07119.12 KXS99042.1 - 0.048 14.1 0.2 0.16 12.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1375) Glucos_trans_II PF14264.6 KXS99042.1 - 0.81 9.0 5.6 0.45 9.8 3.8 1.4 1 1 0 1 1 1 0 Glucosyl transferase GtrII DUF4203 PF13886.6 KXS99043.1 - 2.9e-49 167.5 23.8 3.7e-49 167.1 23.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Spt20 PF12090.8 KXS99044.1 - 1.3 8.6 10.5 0.097 12.3 6.0 1.6 2 0 0 2 2 2 0 Spt20 family AA_permease PF00324.21 KXS99045.1 - 2.4e-136 455.1 47.7 3e-136 454.8 47.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXS99045.1 - 3.6e-45 154.6 51.5 4.6e-45 154.2 51.5 1.1 1 0 0 1 1 1 1 Amino acid permease T_cell_tran_alt PF15128.6 KXS99045.1 - 0.46 10.3 2.3 3.4 7.6 0.1 3.2 2 1 1 3 3 3 0 T-cell leukemia translocation-altered DUF4579 PF15158.6 KXS99045.1 - 1.7 8.3 4.3 10 5.8 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4579) ABC2_membrane PF01061.24 KXS99046.1 - 1.2e-30 106.5 30.3 1.8e-30 106.0 30.3 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KXS99046.1 - 6.6e-25 88.2 0.1 1.1e-24 87.5 0.1 1.4 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KXS99046.1 - 2.2e-06 27.7 0.2 7e-05 22.8 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KXS99046.1 - 9.4e-06 26.1 0.1 1.6e-05 25.3 0.1 1.3 1 0 0 1 1 1 1 AAA ATPase domain ABC2_membrane_3 PF12698.7 KXS99046.1 - 5.5e-05 22.4 22.4 8.9e-05 21.8 22.1 1.5 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_22 PF13401.6 KXS99046.1 - 5.9e-05 23.4 0.1 0.00023 21.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 KXS99046.1 - 0.00014 21.7 0.1 0.5 10.1 0.0 2.5 3 0 0 3 3 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_13 PF13166.6 KXS99046.1 - 0.00042 19.1 0.2 0.0068 15.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KXS99046.1 - 0.0008 19.7 0.3 0.0013 19.0 0.3 1.3 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 KXS99046.1 - 0.0012 18.4 0.1 0.0025 17.4 0.1 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 KXS99046.1 - 0.0029 17.8 0.1 0.0047 17.1 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KXS99046.1 - 0.0043 16.8 0.1 0.012 15.4 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 KXS99046.1 - 0.0047 16.5 0.1 0.0082 15.7 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXS99046.1 - 0.0051 16.5 0.2 0.0092 15.7 0.2 1.3 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KXS99046.1 - 0.0062 15.6 0.1 0.0093 15.1 0.1 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_7 PF12775.7 KXS99046.1 - 0.011 15.2 0.2 0.023 14.2 0.2 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region MMR_HSR1 PF01926.23 KXS99046.1 - 0.012 15.7 0.1 0.022 14.9 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 KXS99046.1 - 0.016 14.9 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KXS99046.1 - 0.025 15.1 0.1 0.056 14.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KXS99046.1 - 0.026 14.5 0.2 0.048 13.6 0.2 1.4 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.6 KXS99046.1 - 0.037 14.1 0.0 0.071 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_35 PF14516.6 KXS99046.1 - 0.04 12.7 0.0 0.063 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain SRP54 PF00448.22 KXS99046.1 - 0.053 13.1 0.5 0.1 12.2 0.1 1.7 2 0 0 2 2 1 0 SRP54-type protein, GTPase domain AAA_5 PF07728.14 KXS99046.1 - 0.054 13.5 0.0 0.35 10.9 0.1 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Septin PF00735.18 KXS99046.1 - 0.056 12.7 0.1 0.09 12.0 0.1 1.2 1 0 0 1 1 1 0 Septin AAA_23 PF13476.6 KXS99046.1 - 0.064 13.8 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KXS99046.1 - 0.076 13.4 0.1 0.23 11.9 0.1 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.10 KXS99046.1 - 0.11 12.0 0.1 0.21 11.0 0.1 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit TsaE PF02367.17 KXS99046.1 - 0.11 12.5 0.1 0.21 11.6 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Cytidylate_kin PF02224.18 KXS99046.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase IstB_IS21 PF01695.17 KXS99046.1 - 0.15 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase_2 PF01637.18 KXS99046.1 - 0.18 11.7 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea SMC_N PF02463.19 KXS99046.1 - 0.2 11.1 0.0 0.95 8.9 0.0 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain PduV-EutP PF10662.9 KXS99046.1 - 0.21 11.3 0.2 0.43 10.3 0.2 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation adh_short_C2 PF13561.6 KXS99047.1 - 3e-59 200.4 1.3 1.3e-58 198.4 1.3 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS99047.1 - 2.3e-33 115.3 1.1 8.9e-33 113.4 1.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS99047.1 - 4.2e-06 26.8 1.2 2.2e-05 24.4 0.1 2.1 1 1 1 2 2 2 1 KR domain 2-Hacid_dh_C PF02826.19 KXS99047.1 - 0.028 13.8 0.0 0.046 13.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KXS99047.1 - 0.042 14.4 0.2 0.092 13.3 0.2 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent STALD PF18185.1 KXS99047.1 - 0.15 11.4 1.5 0.36 10.1 1.0 1.9 1 1 1 2 2 2 0 Sir2- and TIR-associating SLOG family Voldacs PF03517.13 KXS99048.1 - 3.7e-11 43.3 2.6 2.2e-09 37.5 2.6 2.4 1 1 0 1 1 1 1 Regulator of volume decrease after cellular swelling Complex1_LYR_2 PF13233.6 KXS99050.1 - 3.4e-06 27.7 0.9 5.5e-06 27.0 0.9 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KXS99050.1 - 0.00027 20.9 0.2 0.00055 19.9 0.2 1.6 1 1 0 1 1 1 1 Complex 1 protein (LYR family) R-HINP1I PF11463.8 KXS99050.1 - 0.079 12.4 0.1 0.11 11.9 0.1 1.2 1 1 0 1 1 1 0 R.HinP1I restriction endonuclease SAC3_GANP PF03399.16 KXS99051.1 - 1.4e-92 310.3 0.0 2e-92 309.7 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP family PRP3 PF08572.10 KXS99051.1 - 0.0025 17.6 0.2 0.0025 17.6 0.2 2.6 3 0 0 3 3 3 1 pre-mRNA processing factor 3 (PRP3) Fungal_trans PF04082.18 KXS99052.1 - 8.8e-09 34.8 0.5 1.7e-08 33.8 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS99052.1 - 1.3e-06 28.4 7.1 2.5e-06 27.5 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ANTAR PF03861.14 KXS99052.1 - 0.0053 16.6 0.2 0.02 14.7 0.2 2.0 1 0 0 1 1 1 1 ANTAR domain Fungal_trans PF04082.18 KXS99054.1 - 1.2e-10 40.9 4.1 1.2e-10 40.9 4.1 1.6 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS99054.1 - 9.2e-09 35.3 8.6 1.8e-08 34.3 8.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2841 PF11001.8 KXS99055.1 - 1.2e-28 99.7 1.1 2.4e-28 98.7 1.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) DUF2841 PF11001.8 KXS99056.1 - 1.2e-28 99.7 1.1 2.4e-28 98.7 1.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) DUF2423 PF10338.9 KXS99057.1 - 3.5e-16 59.1 3.4 3.5e-16 59.1 3.4 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF2423) CDC45 PF02724.14 KXS99057.1 - 2.7 6.2 9.4 2.6 6.2 9.4 1.0 1 0 0 1 1 1 0 CDC45-like protein ATG22 PF11700.8 KXS99060.1 - 2.7e-170 567.1 13.2 3.1e-170 566.9 13.2 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_2 PF13347.6 KXS99060.1 - 6.3e-05 21.7 14.6 6.3e-05 21.7 14.6 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein DUF4387 PF14330.6 KXS99061.1 - 1.3e-11 45.0 0.0 1.3e-05 25.8 0.0 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4387) NUDIX PF00293.28 KXS99062.1 - 1.3e-15 57.6 0.0 4.7e-15 55.8 0.0 1.8 2 0 0 2 2 2 1 NUDIX domain NUDIX-like PF09296.11 KXS99062.1 - 3.9e-13 49.9 0.0 1.5e-12 48.0 0.0 2.0 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 KXS99062.1 - 1.4e-05 24.6 1.4 2.8e-05 23.7 1.4 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain zf-CHCC PF10276.9 KXS99063.1 - 4.6e-16 58.6 1.9 4.6e-16 58.6 1.9 1.6 2 0 0 2 2 2 1 Zinc-finger domain Sulfatase PF00884.23 KXS99064.1 - 1.1e-73 248.4 0.0 1.9e-73 247.6 0.0 1.4 1 1 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 KXS99064.1 - 0.00041 21.1 0.1 0.059 14.1 0.0 3.1 2 1 0 2 2 2 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 KXS99064.1 - 0.0025 17.5 0.2 0.044 13.4 0.2 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KXS99064.1 - 0.071 11.7 0.0 0.21 10.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF229) DUF4976 PF16347.5 KXS99064.1 - 0.096 13.0 0.2 0.41 10.9 0.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4976) ARD PF03079.14 KXS99065.1 - 1.4e-44 152.1 0.0 1.8e-44 151.7 0.0 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 KXS99065.1 - 6.6e-10 38.6 0.1 1.1e-09 37.8 0.1 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KXS99065.1 - 5.2e-06 26.4 0.0 8.3e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 KXS99065.1 - 0.0094 15.6 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 KXS99065.1 - 0.053 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_6 PF12852.7 KXS99065.1 - 0.097 12.4 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Cupin RNA_pol_I_TF PF04090.12 KXS99066.1 - 0.0075 15.8 0.0 0.014 14.9 0.0 1.4 1 1 1 2 2 2 1 RNA polymerase I specific initiation factor polyprenyl_synt PF00348.17 KXS99068.1 - 3e-95 318.1 0.1 3.8e-95 317.8 0.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase RNase_H2-Ydr279 PF09468.10 KXS99068.1 - 0.02 15.1 0.6 0.13 12.5 0.2 2.2 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) wHTH domain PINIT PF14324.6 KXS99069.1 - 8.8e-35 120.2 1.8 1.2e-34 119.8 0.0 2.1 2 0 0 2 2 2 1 PINIT domain zf-MIZ PF02891.20 KXS99069.1 - 2.4e-20 72.0 2.3 3.5e-20 71.5 1.5 1.8 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KXS99069.1 - 1.3e-07 31.3 1.4 3.1e-07 30.1 0.3 2.1 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.27 KXS99069.1 - 3.4e-05 23.5 0.0 6.1e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 SAP domain SUIM_assoc PF16619.5 KXS99069.1 - 0.036 14.1 5.8 0.072 13.2 4.3 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF4127 PF13552.6 KXS99071.1 - 0.06 11.9 0.0 0.089 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4127) PAN_4 PF14295.6 KXS99072.1 - 3.5e-08 33.2 0.4 6.1e-08 32.5 0.4 1.4 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 KXS99072.1 - 0.0029 17.5 0.0 0.0043 17.0 0.0 1.3 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.12 KXS99072.1 - 0.054 13.3 0.1 0.089 12.6 0.1 1.3 1 0 0 1 1 1 0 PAN-like domain YhhN PF07947.14 KXS99075.1 - 0.013 15.2 0.4 0.12 12.0 0.1 2.2 2 0 0 2 2 2 0 YhhN family UPF0506 PF11703.8 KXS99075.1 - 0.062 13.7 0.3 0.062 13.7 0.3 1.7 2 0 0 2 2 2 0 UPF0506 ANAPC8 PF04049.13 KXS99076.1 - 1.5e-50 170.9 0.3 3.6e-50 169.7 0.1 1.8 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.28 KXS99076.1 - 4.7e-18 64.2 19.4 4.2e-06 26.4 0.0 6.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 KXS99076.1 - 7.8e-16 56.9 15.1 2.1e-06 27.5 0.0 6.9 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 KXS99076.1 - 1.2e-15 56.2 28.9 0.0014 18.6 0.0 7.8 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 KXS99076.1 - 3.2e-14 52.4 21.0 0.0015 19.2 0.1 8.5 8 2 2 10 10 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 KXS99076.1 - 2.2e-12 46.5 3.8 1.2e-06 28.1 0.7 4.5 3 1 1 4 4 4 3 TPR repeat TPR_16 PF13432.6 KXS99076.1 - 5.6e-09 36.5 16.4 0.00039 21.0 0.0 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXS99076.1 - 8.7e-08 32.6 15.4 0.014 15.9 0.5 6.3 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXS99076.1 - 1.1e-07 32.1 9.0 0.55 10.6 0.0 5.8 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXS99076.1 - 8.1e-06 25.5 18.9 0.4 10.8 0.3 6.7 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 KXS99076.1 - 0.00034 20.7 18.1 0.027 14.6 0.2 5.2 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 KXS99076.1 - 0.00094 19.7 13.7 0.13 12.9 0.4 5.4 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 KXS99076.1 - 0.0015 18.7 9.3 6.6 7.4 0.1 6.0 6 0 0 6 6 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KXS99076.1 - 0.0021 18.3 7.4 2.2 8.5 2.1 5.0 3 2 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 KXS99076.1 - 0.01 15.1 6.0 1.2 8.3 0.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat YfiO PF13525.6 KXS99076.1 - 0.027 14.2 0.3 0.065 12.9 0.3 1.5 1 0 0 1 1 1 0 Outer membrane lipoprotein ChAPs PF09295.10 KXS99076.1 - 0.031 13.3 0.0 4.5 6.2 0.0 2.3 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF3808 PF10300.9 KXS99076.1 - 0.056 12.2 0.1 0.056 12.2 0.1 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3808) DUF3856 PF12968.7 KXS99076.1 - 0.11 12.5 2.1 1.8 8.6 0.1 3.3 2 1 1 3 3 3 0 Domain of Unknown Function (DUF3856) LZ_Tnp_IS66 PF13007.7 KXS99076.1 - 0.21 12.4 0.1 0.21 12.4 0.1 2.4 2 0 0 2 2 1 0 Transposase C of IS166 homeodomain TPR_10 PF13374.6 KXS99076.1 - 0.79 9.7 15.3 19 5.3 0.1 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat PX PF00787.24 KXS99083.1 - 1.7e-24 85.9 0.1 2.3e-24 85.6 0.1 1.1 1 0 0 1 1 1 1 PX domain Ribosomal_S4e PF00900.20 KXS99084.1 - 1.2e-37 127.6 0.3 2.4e-37 126.6 0.3 1.5 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 KXS99084.1 - 5.6e-24 83.5 0.0 9.8e-24 82.7 0.0 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 KXS99084.1 - 1.5e-17 63.4 6.5 2.7e-17 62.6 6.5 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 KXS99084.1 - 6e-10 38.7 0.1 1.3e-09 37.7 0.1 1.6 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 KXS99084.1 - 0.00091 19.1 0.7 0.00091 19.1 0.7 2.9 3 0 0 3 3 3 1 KOW motif ApbA_C PF08546.11 KXS99085.1 - 1.7e-27 96.1 0.0 4.1e-27 94.9 0.0 1.7 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KXS99085.1 - 3.7e-24 85.1 0.1 9.9e-17 61.0 0.0 2.4 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA GPI-anchored PF10342.9 KXS99085.1 - 7.9e-09 36.2 2.3 1e-08 35.8 0.0 2.3 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Rax2 PF12768.7 KXS99085.1 - 0.03 13.8 0.0 0.054 12.9 0.0 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity MGC-24 PF05283.11 KXS99085.1 - 0.053 14.0 1.2 0.16 12.4 1.2 1.8 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin 2-Hacid_dh_C PF02826.19 KXS99085.1 - 0.059 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Podoplanin PF05808.11 KXS99085.1 - 0.13 12.4 4.2 0.069 13.2 0.5 2.4 3 0 0 3 3 3 0 Podoplanin Methyltransf_31 PF13847.6 KXS99086.1 - 0.018 14.8 0.1 0.043 13.6 0.0 1.8 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 KXS99086.1 - 0.094 13.5 0.0 0.32 11.8 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain UCH PF00443.29 KXS99087.1 - 5.4e-47 160.4 0.0 8.4e-47 159.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXS99087.1 - 1.6e-09 37.8 0.0 4.4e-08 33.1 0.0 2.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase HU-DNA_bdg PF14848.6 KXS99088.1 - 0.99 9.4 5.5 7.1 6.7 0.4 2.5 2 0 0 2 2 2 0 DNA-binding domain SMRP1 PF15181.6 KXS99091.1 - 0.047 13.3 0.4 0.13 11.9 0.0 1.8 1 1 1 2 2 2 0 Spermatid-specific manchette-related protein 1 MFS_1 PF07690.16 KXS99092.1 - 1.3e-28 100.0 31.5 1.7e-28 99.6 31.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ADH_N PF08240.12 KXS99095.1 - 5.4e-21 74.5 1.4 1.1e-20 73.5 1.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXS99095.1 - 1.9e-11 44.1 0.0 3.4e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KXS99095.1 - 0.00016 21.0 0.1 0.00034 20.0 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KXS99095.1 - 0.0059 15.9 0.2 0.0099 15.2 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain BTRD1 PF17660.1 KXS99095.1 - 0.11 12.3 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial tandem repeat domain 1 Cloacin_immun PF03513.14 KXS99095.1 - 0.12 12.8 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 Cloacin immunity protein Coq4 PF05019.13 KXS99098.1 - 7.8e-98 326.2 0.0 9.6e-98 325.9 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 MORN PF02493.20 KXS99099.1 - 0.28 11.1 0.6 0.62 10.1 0.6 1.6 1 0 0 1 1 1 0 MORN repeat zf-Sec23_Sec24 PF04810.15 KXS99100.1 - 0.013 15.6 2.2 0.013 15.6 2.2 3.9 4 2 1 5 5 5 0 Sec23/Sec24 zinc finger DUF1772 PF08592.11 KXS99102.1 - 0.13 12.6 6.8 0.11 12.8 2.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) Med21 PF11221.8 KXS99103.1 - 1.3e-45 155.2 1.5 1.5e-45 155.0 1.5 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Med9 PF07544.13 KXS99103.1 - 5.4e-05 23.2 1.6 0.0012 18.9 0.6 2.4 1 1 1 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 KIX PF02172.16 KXS99103.1 - 0.00076 19.7 0.2 0.0014 18.8 0.2 1.4 1 0 0 1 1 1 1 KIX domain Spore_III_AB PF09548.10 KXS99103.1 - 0.0091 16.1 1.1 0.01 15.9 0.3 1.4 2 0 0 2 2 2 1 Stage III sporulation protein AB (spore_III_AB) DUF1178 PF06676.11 KXS99103.1 - 0.048 14.0 1.4 0.065 13.6 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) Herpes_UL6 PF01763.16 KXS99103.1 - 0.12 10.8 0.6 0.14 10.7 0.6 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like HSP70 PF00012.20 KXS99105.1 - 4.9e-74 249.6 3.2 4.9e-74 249.6 3.2 1.5 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 KXS99105.1 - 6.5e-09 35.1 0.4 1.2e-08 34.2 0.4 1.4 1 0 0 1 1 1 1 MreB/Mbl protein PilM_2 PF11104.8 KXS99105.1 - 0.0027 16.8 0.1 0.96 8.4 0.0 2.3 2 0 0 2 2 2 2 Type IV pilus assembly protein PilM; PHD PF00628.29 KXS99107.1 - 7.4e-07 29.0 9.1 1.5e-06 28.0 9.1 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KXS99107.1 - 0.00026 20.5 1.7 0.00065 19.2 1.7 1.7 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KXS99107.1 - 0.014 15.6 3.6 0.015 15.5 2.0 1.9 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KXS99107.1 - 0.026 14.7 0.5 0.099 12.8 0.3 2.0 2 0 0 2 2 2 0 PHD-zinc-finger like domain ANTH PF07651.16 KXS99108.1 - 2.9e-76 256.1 6.9 1e-75 254.3 0.0 3.5 3 1 0 3 3 3 1 ANTH domain I_LWEQ PF01608.17 KXS99108.1 - 5.2e-56 189.1 7.2 5.2e-56 189.1 7.2 6.2 4 1 1 6 6 6 2 I/LWEQ domain TcdB_N PF12918.7 KXS99108.1 - 0.004 17.4 1.4 0.004 17.4 1.4 3.7 5 0 0 5 5 5 1 TcdB toxin N-terminal helical domain Ion_trans_2 PF07885.16 KXS99109.1 - 1.9e-17 63.0 5.9 3.1e-17 62.3 5.9 1.3 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 KXS99109.1 - 0.00037 19.8 3.9 0.00057 19.2 3.9 1.2 1 0 0 1 1 1 1 Ion transport protein Lig_chan PF00060.26 KXS99109.1 - 0.00055 19.8 1.8 0.00092 19.1 1.0 1.8 2 0 0 2 2 2 1 Ligand-gated ion channel Ion_trans_2 PF07885.16 KXS99110.1 - 4.3e-14 52.2 3.0 4.3e-14 52.2 3.0 2.9 2 1 1 3 3 3 1 Ion channel DUF5090 PF17009.5 KXS99110.1 - 0.31 11.0 2.3 0.26 11.2 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5090) Ion_trans_2 PF07885.16 KXS99111.1 - 1.2e-28 98.9 26.2 6.2e-17 61.3 5.9 3.3 3 1 0 3 3 3 2 Ion channel Ion_trans PF00520.31 KXS99111.1 - 9.1e-06 25.1 9.7 0.0012 18.2 3.9 2.6 2 1 1 3 3 3 2 Ion transport protein Lig_chan PF00060.26 KXS99111.1 - 0.0018 18.2 4.1 0.002 17.9 1.0 2.6 2 1 1 3 3 3 1 Ligand-gated ion channel Aminotran_5 PF00266.19 KXS99112.1 - 3.8e-23 82.1 0.0 6.4e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KXS99112.1 - 1.3e-06 27.9 0.0 2.2e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KXS99112.1 - 0.00011 20.9 0.0 0.00015 20.4 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KXS99112.1 - 0.00012 21.5 0.2 0.0004 19.8 0.2 1.7 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Asp PF00026.23 KXS99113.1 - 3.6e-07 29.9 0.6 1.3e-05 24.8 0.6 2.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease SKG6 PF08693.10 KXS99113.1 - 0.012 15.0 3.8 0.022 14.2 3.8 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain VSP PF03302.13 KXS99113.1 - 0.053 12.4 0.6 0.096 11.5 0.6 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF2681 PF10883.8 KXS99113.1 - 0.074 13.5 0.3 0.14 12.6 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) DUF4381 PF14316.6 KXS99113.1 - 0.12 12.6 0.4 0.24 11.6 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Exop_C PF18559.1 KXS99113.1 - 0.18 11.7 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 Galactose-binding domain-like Bacteriocin_IIc PF10439.9 KXS99113.1 - 8.8 6.5 10.4 23 5.2 10.4 1.7 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide GMC_oxred_N PF00732.19 KXS99114.1 - 0.026 13.9 0.0 0.029 13.7 0.0 1.1 1 0 0 1 1 1 0 GMC oxidoreductase KH_6 PF15985.5 KXS99115.1 - 2.4e-18 66.2 0.4 4.9e-18 65.2 0.4 1.6 1 0 0 1 1 1 1 KH domain Rrp40_N PF18311.1 KXS99115.1 - 5.2e-14 51.9 3.8 9.7e-14 51.0 2.0 2.1 2 0 0 2 2 2 1 Exosome complex exonuclease Rrp40 N-terminal domain DUF4388 PF14332.6 KXS99115.1 - 0.044 14.0 0.0 1.6 9.0 0.0 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4388) TPR_11 PF13414.6 KXS99116.1 - 1.2e-07 31.3 0.6 5.8e-05 22.7 0.0 4.1 3 1 1 4 4 4 1 TPR repeat TPR_1 PF00515.28 KXS99116.1 - 2.6e-07 30.2 0.8 0.00036 20.2 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXS99116.1 - 2.3e-06 27.3 0.1 0.00022 21.2 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 KXS99116.1 - 6.8e-06 26.1 0.2 0.065 13.6 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXS99116.1 - 8.2e-06 25.6 8.8 0.00024 21.0 0.0 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXS99116.1 - 0.014 15.5 0.7 0.014 15.5 0.7 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXS99116.1 - 0.016 16.0 0.5 0.016 16.0 0.5 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KXS99116.1 - 0.14 12.7 0.2 0.14 12.7 0.2 3.7 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 KXS99116.1 - 0.49 10.5 1.7 23 5.3 0.1 4.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXS99116.1 - 1.9 8.9 4.4 19 5.6 0.1 4.0 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KXS99116.1 - 4.6 8.0 11.6 0.07 13.8 0.7 3.2 3 1 1 4 4 2 0 Tetratricopeptide repeat PHD PF00628.29 KXS99117.1 - 0.00016 21.5 8.1 0.00025 20.9 8.1 1.3 1 0 0 1 1 1 1 PHD-finger Pox_C4_C10 PF03336.13 KXS99117.1 - 0.078 12.1 0.1 0.11 11.6 0.1 1.1 1 0 0 1 1 1 0 Poxvirus C4/C10 protein FANCL_C PF11793.8 KXS99117.1 - 0.75 10.0 5.3 0.45 10.7 2.2 2.0 2 0 0 2 2 2 0 FANCL C-terminal domain PHD_2 PF13831.6 KXS99117.1 - 2.1 7.9 6.5 0.44 10.1 2.8 1.8 2 0 0 2 2 2 0 PHD-finger DNA_pol_phi PF04931.13 KXS99120.1 - 0.0037 15.4 21.8 0.0043 15.2 21.8 1.0 1 0 0 1 1 1 1 DNA polymerase phi SAPS PF04499.15 KXS99120.1 - 0.0073 15.2 0.6 0.0073 15.2 0.6 1.0 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein NPR3 PF03666.13 KXS99120.1 - 0.011 14.6 0.4 0.011 14.6 0.4 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Nop14 PF04147.12 KXS99120.1 - 0.019 13.2 16.5 0.021 13.1 16.5 1.0 1 0 0 1 1 1 0 Nop14-like family RNA_pol_Rpc4 PF05132.14 KXS99120.1 - 0.026 15.0 0.7 0.029 14.8 0.7 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 Tim54 PF11711.8 KXS99120.1 - 0.027 13.3 5.4 0.032 13.0 5.4 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SDA1 PF05285.12 KXS99120.1 - 0.038 13.4 15.4 0.041 13.3 15.4 1.0 1 0 0 1 1 1 0 SDA1 Cytomega_UL84 PF06284.11 KXS99120.1 - 0.063 11.7 5.8 0.071 11.6 5.8 1.0 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Pox_Ag35 PF03286.14 KXS99120.1 - 0.1 12.4 11.4 0.14 12.0 11.4 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF913 PF06025.12 KXS99120.1 - 0.1 11.5 0.6 0.1 11.6 0.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Afi1 PF07792.12 KXS99120.1 - 0.11 13.0 9.9 1.4 9.4 10.5 2.0 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF4820 PF16091.5 KXS99120.1 - 0.12 11.7 4.2 0.15 11.4 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Zip PF02535.22 KXS99120.1 - 0.15 11.3 0.7 0.16 11.2 0.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter BUD22 PF09073.10 KXS99120.1 - 0.18 11.1 13.3 0.2 10.9 13.3 1.0 1 0 0 1 1 1 0 BUD22 CPSF100_C PF13299.6 KXS99120.1 - 0.2 11.8 2.7 0.22 11.7 2.7 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Presenilin PF01080.17 KXS99120.1 - 0.26 10.0 2.9 0.3 9.8 2.9 1.0 1 0 0 1 1 1 0 Presenilin DUF5523 PF17661.1 KXS99120.1 - 0.27 10.9 13.6 0.33 10.6 13.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Drc1-Sld2 PF11719.8 KXS99120.1 - 0.5 9.8 9.5 0.55 9.7 9.5 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein MRNIP PF15749.5 KXS99120.1 - 0.51 11.1 5.6 0.73 10.6 5.6 1.4 1 0 0 1 1 1 0 MRN-interacting protein TRAP_alpha PF03896.16 KXS99120.1 - 0.57 9.3 10.7 0.68 9.1 10.7 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit eIF_4EBP PF05456.11 KXS99120.1 - 1.1 9.2 4.0 1.6 8.7 4.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) CDC45 PF02724.14 KXS99120.1 - 1.3 7.2 15.5 1.6 7.0 15.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Trypan_PARP PF05887.11 KXS99120.1 - 1.5 8.8 18.5 2 8.4 18.5 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF2722 PF10846.8 KXS99120.1 - 2.5 7.0 13.9 3 6.7 13.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) O-antigen_lig PF13425.6 KXS99120.1 - 2.7 6.7 4.2 3 6.5 4.2 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Myc_N PF01056.18 KXS99120.1 - 6.5 6.6 11.5 8.5 6.2 11.5 1.1 1 0 0 1 1 1 0 Myc amino-terminal region TFB6 PF17110.5 KXS99120.1 - 6.6 6.5 11.7 9.9 5.9 11.7 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Auts2 PF15336.6 KXS99120.1 - 7.1 6.7 8.1 8.9 6.4 8.1 1.1 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein DUF4637 PF15470.6 KXS99120.1 - 7.8 6.2 18.2 12 5.6 18.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Pkinase_Tyr PF07714.17 KXS99121.1 - 0.21 10.8 0.0 0.28 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 KXS99122.1 - 1.2e-12 47.7 0.0 1.3e-11 44.4 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS99122.1 - 4.9e-07 29.3 0.0 1.8e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Metal_resist PF13801.6 KXS99122.1 - 5.7 7.1 14.1 1.7 8.8 0.9 3.9 4 0 0 4 4 4 0 Heavy-metal resistance Phosphoesterase PF04185.14 KXS99123.1 - 5.7e-28 98.1 0.0 6.2e-28 98.0 0.0 1.0 1 0 0 1 1 1 1 Phosphoesterase family Pkinase PF00069.25 KXS99124.1 - 6.4e-09 35.6 0.0 1.3e-08 34.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS99124.1 - 0.028 13.7 0.0 0.18 11.1 0.0 2.2 1 1 1 2 2 2 0 Protein tyrosine kinase RasGAP_C PF03836.15 KXS99124.1 - 0.27 11.4 0.4 0.5 10.5 0.4 1.3 1 0 0 1 1 1 0 RasGAP C-terminus EHN PF06441.12 KXS99125.1 - 6.8e-34 116.5 2.8 1.1e-33 115.8 0.3 2.2 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KXS99125.1 - 2.8e-12 46.9 0.0 5.6e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXS99125.1 - 0.012 16.3 1.3 0.018 15.7 1.2 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Bacteriocin_IIc PF10439.9 KXS99126.1 - 0.23 11.6 0.1 0.45 10.7 0.1 1.3 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide ZapB PF06005.12 KXS99126.1 - 0.33 11.4 46.0 0.29 11.6 5.7 6.6 2 1 4 6 6 6 0 Cell division protein ZapB EccE PF11203.8 KXS99126.1 - 1.8 8.9 7.4 1.6 9.1 0.3 3.1 3 1 0 3 3 3 0 Putative type VII ESX secretion system translocon, EccE HMMR_N PF15905.5 KXS99126.1 - 2.3 7.6 42.6 0.43 10.0 19.2 2.2 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Cut8 PF08559.10 KXS99127.1 - 0.084 12.5 0.0 0.098 12.3 0.0 1.0 1 0 0 1 1 1 0 Cut8, nuclear proteasome tether protein NMT_C PF02799.15 KXS99127.1 - 0.12 11.9 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain UQ_con PF00179.26 KXS99134.1 - 2.6e-42 143.8 0.0 3.6e-42 143.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 KXS99134.1 - 9.1e-05 22.2 0.0 0.00018 21.3 0.0 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.6 KXS99134.1 - 0.003 17.2 0.0 0.005 16.5 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B DUF1421 PF07223.11 KXS99134.1 - 0.038 13.8 0.3 0.07 13.0 0.3 1.3 1 0 0 1 1 1 0 UBA-like domain (DUF1421) Sugar_tr PF00083.24 KXS99136.1 - 1.5e-104 350.4 23.8 1.7e-104 350.3 23.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS99136.1 - 6.8e-23 81.1 25.4 2.7e-22 79.2 17.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily E1-E2_ATPase PF00122.20 KXS99137.1 - 1.1e-33 116.3 14.8 4.4e-27 94.8 0.0 2.7 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KXS99137.1 - 1.8e-23 83.2 0.8 1.8e-23 83.2 0.8 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KXS99137.1 - 1.4e-18 67.9 0.0 6.3e-18 65.8 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXS99137.1 - 2.1e-17 62.5 0.1 4.9e-17 61.4 0.1 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Glyco_transf_8 PF01501.20 KXS99137.1 - 6.9e-13 48.7 0.4 1.2e-12 47.9 0.4 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Cation_ATPase PF13246.6 KXS99137.1 - 1.2e-12 47.8 0.0 2.3e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KXS99137.1 - 1.3e-06 28.4 1.8 1.9e-05 24.6 0.5 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Mannosyl_trans3 PF11051.8 KXS99137.1 - 7.6e-05 22.2 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Fasciclin PF02469.22 KXS99138.1 - 4.2e-14 52.9 0.0 9.9e-10 38.7 0.0 2.7 2 1 0 2 2 2 2 Fasciclin domain WD40 PF00400.32 KXS99139.1 - 1.6e-11 44.5 17.4 0.0011 19.7 0.8 6.3 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS99139.1 - 0.024 14.9 0.0 0.53 10.6 0.0 2.8 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain GCIP PF13324.6 KXS99139.1 - 0.11 12.1 1.9 0.16 11.5 1.9 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting MraZ PF02381.18 KXS99139.1 - 0.11 12.4 0.0 16 5.6 0.0 2.6 2 0 0 2 2 2 0 MraZ protein, putative antitoxin-like TFIIF_alpha PF05793.12 KXS99139.1 - 0.21 10.1 10.5 0.015 13.9 5.2 1.7 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RXT2_N PF08595.11 KXS99139.1 - 0.35 10.9 5.2 0.93 9.5 5.2 1.8 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.12 KXS99139.1 - 0.35 10.2 12.5 0.59 9.4 12.5 1.3 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 KXS99139.1 - 3.2 5.8 10.0 4.6 5.2 10.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi RRN3 PF05327.11 KXS99139.1 - 7.2 5.0 5.3 8.9 4.7 5.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Promethin PF16015.5 KXS99140.1 - 1.7e-28 98.6 15.4 2.3e-28 98.2 15.4 1.2 1 0 0 1 1 1 1 Promethin DUF2207 PF09972.9 KXS99140.1 - 0.2 10.4 1.5 0.24 10.1 1.5 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Methyltransf_23 PF13489.6 KXS99142.1 - 6.7e-15 55.3 0.0 9.9e-15 54.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS99142.1 - 1.8e-11 44.6 0.0 5.1e-11 43.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS99142.1 - 1.3e-07 32.2 0.0 2.7e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS99142.1 - 1.3e-05 25.1 0.0 0.00017 21.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS99142.1 - 0.0014 19.4 0.0 0.0078 16.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KXS99142.1 - 0.002 17.5 0.0 0.0041 16.4 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 KXS99142.1 - 0.004 16.6 0.0 0.0095 15.4 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Rsm22 PF09243.10 KXS99142.1 - 0.0043 16.4 0.0 0.0064 15.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 MTS PF05175.14 KXS99142.1 - 0.008 15.7 0.0 0.013 15.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 KXS99142.1 - 0.044 13.9 0.0 0.069 13.2 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 KXS99142.1 - 0.056 12.9 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_2 PF00891.18 KXS99142.1 - 0.072 12.4 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_16 PF10294.9 KXS99142.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase CH PF00307.31 KXS99143.1 - 6.2e-44 148.6 0.1 7.2e-23 80.9 0.0 2.8 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 KXS99143.1 - 1.4e-24 86.0 0.1 4e-24 84.5 0.1 1.9 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 KXS99143.1 - 1.5e-09 37.6 0.1 1.6e-05 24.6 0.0 2.8 2 0 0 2 2 2 2 CAMSAP CH domain EF-hand_6 PF13405.6 KXS99143.1 - 0.0019 18.0 0.6 0.094 12.7 0.0 3.3 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 KXS99143.1 - 0.0053 16.2 0.8 1 9.1 0.0 3.2 3 0 0 3 3 3 1 EF hand PBD PF00786.28 KXS99143.1 - 0.023 15.1 1.0 0.09 13.2 1.0 2.1 1 0 0 1 1 1 0 P21-Rho-binding domain EF-hand_8 PF13833.6 KXS99143.1 - 0.087 12.7 1.0 1.1 9.2 0.0 2.7 3 0 0 3 3 3 0 EF-hand domain pair zf-RRPl_C4 PF17026.5 KXS99143.1 - 0.098 12.8 0.1 0.25 11.5 0.1 1.7 2 0 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type DUF2884 PF11101.8 KXS99143.1 - 0.26 10.7 1.3 0.32 10.5 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) EF-hand_7 PF13499.6 KXS99143.1 - 2.9 8.4 7.5 0.55 10.7 0.4 3.2 4 0 0 4 4 4 0 EF-hand domain pair Alginate_lyase2 PF08787.11 KXS99144.1 - 0.027 14.3 0.0 0.028 14.3 0.0 1.1 1 0 0 1 1 1 0 Alginate lyase RNA_pol_I_A49 PF06870.12 KXS99145.1 - 1.1e-80 271.3 2.0 1.3e-80 271.1 2.0 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor AAA PF00004.29 KXS99147.1 - 7.3e-41 139.7 0.0 1.3e-40 138.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXS99147.1 - 1.5e-10 40.7 0.4 2.9e-10 39.8 0.4 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 KXS99147.1 - 6.6e-10 38.8 0.2 1.3e-09 37.9 0.2 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 KXS99147.1 - 5.6e-06 26.6 0.0 1.1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KXS99147.1 - 6.1e-06 26.5 0.2 0.0059 16.9 0.2 2.5 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 KXS99147.1 - 1.2e-05 24.7 0.0 2.1e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 KXS99147.1 - 0.0001 22.3 0.1 0.00029 20.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXS99147.1 - 0.0002 21.8 0.2 0.0055 17.1 0.1 2.3 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KXS99147.1 - 0.00027 20.7 0.0 0.00053 19.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KXS99147.1 - 0.0031 18.1 0.0 0.0064 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KXS99147.1 - 0.0039 17.4 0.9 0.0077 16.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KXS99147.1 - 0.0079 16.4 0.1 0.027 14.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 KXS99147.1 - 0.017 14.6 0.7 0.52 9.7 0.1 2.2 2 0 0 2 2 2 0 PhoH-like protein IstB_IS21 PF01695.17 KXS99147.1 - 0.018 14.8 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 KXS99147.1 - 0.018 15.1 0.0 0.037 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 KXS99147.1 - 0.018 14.3 0.3 0.041 13.1 0.1 1.7 2 1 0 2 2 1 0 TIP49 P-loop domain NACHT PF05729.12 KXS99147.1 - 0.018 15.0 0.2 0.63 9.9 0.1 2.6 2 1 1 3 3 3 0 NACHT domain ATPase PF06745.13 KXS99147.1 - 0.019 14.3 0.1 0.5 9.7 0.1 2.2 1 1 0 2 2 2 0 KaiC AAA_3 PF07726.11 KXS99147.1 - 0.02 14.7 0.0 0.041 13.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Prot_ATP_OB_N PF17758.1 KXS99147.1 - 0.027 14.1 0.2 0.3 10.8 0.0 2.4 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain RNA_helicase PF00910.22 KXS99147.1 - 0.051 14.0 0.0 0.099 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 KXS99147.1 - 0.061 12.7 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 KXS99147.1 - 0.069 12.4 0.0 0.19 11.0 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.6 KXS99147.1 - 0.11 12.0 1.2 0.66 9.5 0.4 2.3 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.6 KXS99147.1 - 0.13 12.0 0.3 0.31 10.8 0.3 1.8 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KXS99147.1 - 0.16 11.2 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 KXS99147.1 - 0.2 11.1 0.1 0.52 9.8 0.1 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region PNP_UDP_1 PF01048.20 KXS99148.1 - 6.3e-52 176.2 0.0 8.6e-52 175.7 0.0 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily Fcf2 PF08698.11 KXS99152.1 - 5e-38 129.4 3.9 5.6e-38 129.3 0.2 2.7 2 1 1 3 3 3 1 Fcf2 pre-rRNA processing FDX-ACB PF03147.14 KXS99152.1 - 0.037 14.5 0.2 0.11 12.9 0.2 1.8 1 0 0 1 1 1 0 Ferredoxin-fold anticodon binding domain DUF2922 PF11148.8 KXS99152.1 - 0.056 13.2 0.2 0.64 9.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2922) Seryl_tRNA_N PF02403.22 KXS99152.1 - 4.5 7.6 9.6 0.18 12.0 1.0 2.7 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain COG2 PF06148.11 KXS99153.1 - 4.8e-28 97.9 1.5 5.1e-28 97.8 0.1 1.7 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 KXS99153.1 - 4e-07 30.0 0.2 1.5e-06 28.2 0.0 2.0 2 0 0 2 2 2 1 Vps51/Vps67 COG5 PF10392.9 KXS99153.1 - 0.005 17.0 0.0 0.012 15.8 0.0 1.6 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Vps54_N PF10475.9 KXS99153.1 - 0.09 12.0 0.0 0.39 9.9 0.0 1.8 2 0 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex p450 PF00067.22 KXS99154.1 - 4e-17 62.1 0.1 7.6e-16 57.9 0.1 2.2 1 1 0 1 1 1 1 Cytochrome P450 ARL17 PF15840.5 KXS99154.1 - 0.23 11.8 1.8 26 5.3 0.0 3.0 3 0 0 3 3 3 0 ADP-ribosylation factor-like protein 17 Ribosomal_S10 PF00338.22 KXS99155.1 - 2.3e-24 85.5 0.0 4.9e-24 84.4 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e p450 PF00067.22 KXS99156.1 - 4.2e-44 151.1 0.0 5.7e-44 150.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 UFD1 PF03152.14 KXS99157.1 - 1.2e-69 233.2 0.0 1.6e-69 232.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 RFX_DNA_binding PF02257.15 KXS99158.1 - 4e-28 97.8 0.0 7.6e-28 97.0 0.0 1.5 1 0 0 1 1 1 1 RFX DNA-binding domain DUF4448 PF14610.6 KXS99159.1 - 0.078 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF2989 PF11207.8 KXS99161.1 - 0.11 12.3 0.1 0.13 12.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2989) ANAPC4 PF12896.7 KXS99164.1 - 4.4e-44 150.4 0.0 6e-44 150.0 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 KXS99164.1 - 3.8e-13 49.6 0.0 2e-12 47.2 0.0 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Proteasome PF00227.26 KXS99165.1 - 3.8e-46 157.0 0.0 5.1e-46 156.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KXS99165.1 - 2.7e-12 46.1 0.3 4.7e-12 45.4 0.3 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Flg_hook PF02120.16 KXS99165.1 - 0.049 13.5 1.5 14 5.6 0.0 3.1 2 1 1 3 3 3 0 Flagellar hook-length control protein FliK Apt1 PF10351.9 KXS99166.1 - 5.9e-193 642.1 1.8 5.9e-193 642.1 1.8 3.8 3 0 0 3 3 3 1 Golgi-body localisation protein domain Fmp27 PF10344.9 KXS99166.1 - 7.5e-185 616.6 0.0 1.2e-184 615.9 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Fmp27_WPPW PF10359.9 KXS99166.1 - 1.8e-171 571.3 1.0 1.8e-171 571.3 1.0 2.2 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.9 KXS99166.1 - 2.4e-57 193.4 0.0 6.5e-57 192.0 0.0 1.8 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 KXS99166.1 - 3.2e-54 183.1 0.4 6.9e-54 182.0 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 KXS99166.1 - 2.7e-30 105.1 4.6 1.6e-29 102.7 0.0 3.6 3 0 0 3 3 3 1 RNA pol II promoter Fmp27 protein domain Fn_bind PF02986.14 KXS99166.1 - 0.73 9.6 5.2 0.47 10.2 1.8 2.5 3 0 0 3 3 3 0 Fibronectin binding repeat SKA2 PF16740.5 KXS99166.1 - 1 9.2 4.2 0.8 9.5 1.6 2.2 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Asp_protease_2 PF13650.6 KXS99167.1 - 0.0003 21.4 0.0 0.0004 21.0 0.0 1.4 1 1 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KXS99167.1 - 0.00094 19.7 0.0 0.0015 19.0 0.0 1.5 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 KXS99167.1 - 0.019 14.7 0.1 0.022 14.5 0.1 1.1 1 0 0 1 1 1 0 Putative peptidase (DUF1758) PapC_N PF13954.6 KXS99167.1 - 0.11 12.5 0.1 0.11 12.5 0.1 1.1 1 0 0 1 1 1 0 PapC N-terminal domain ATP-sulfurylase PF01747.17 KXS99169.1 - 0.051 13.0 0.1 0.068 12.6 0.1 1.1 1 0 0 1 1 1 0 ATP-sulfurylase Pyr_redox_2 PF07992.14 KXS99170.1 - 7.2e-44 150.2 2.1 1.2e-43 149.5 2.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 KXS99170.1 - 4.6e-20 71.7 0.0 9.3e-20 70.7 0.0 1.5 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox PF00070.27 KXS99170.1 - 3.8e-17 62.6 5.3 4.3e-15 56.0 0.8 3.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 KXS99170.1 - 1.7e-15 56.8 0.0 5.3e-15 55.2 0.0 1.9 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain Rieske PF00355.26 KXS99170.1 - 2.7e-14 52.9 0.1 1.8e-13 50.2 0.0 2.4 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Fer2_BFD PF04324.15 KXS99170.1 - 8.8e-14 51.6 5.6 1.1e-11 44.9 4.3 2.6 2 0 0 2 2 2 1 BFD-like [2Fe-2S] binding domain NIR_SIR_ferr PF03460.17 KXS99170.1 - 6e-10 38.8 0.0 1.8e-09 37.3 0.0 1.8 2 0 0 2 2 2 1 Nitrite/Sulfite reductase ferredoxin-like half domain Amino_oxidase PF01593.24 KXS99170.1 - 5.7e-07 29.2 0.4 0.0083 15.5 0.0 2.4 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase Rubredoxin_C PF18267.1 KXS99170.1 - 9e-06 25.5 0.0 0.037 14.0 0.0 3.4 3 0 0 3 3 3 2 Rubredoxin NAD+ reductase C-terminal domain NAD_binding_9 PF13454.6 KXS99170.1 - 2.2e-05 24.5 1.3 0.74 9.8 0.0 3.6 3 1 1 4 4 4 2 FAD-NAD(P)-binding K_oxygenase PF13434.6 KXS99170.1 - 0.0066 15.6 0.0 0.24 10.5 0.0 2.3 1 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KXS99170.1 - 0.0085 15.7 1.6 1.8 8.0 0.0 3.6 3 1 1 4 4 4 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KXS99170.1 - 0.011 14.4 0.2 8.2 5.0 0.0 3.1 3 0 0 3 3 3 0 HI0933-like protein DUF2420 PF10336.9 KXS99172.1 - 7.2e-28 96.8 0.2 1.2e-27 96.1 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) HU-CCDC81_euk_2 PF18289.1 KXS99172.1 - 0.24 11.6 0.0 0.52 10.5 0.0 1.5 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 2 Homeodomain PF00046.29 KXS99173.1 - 4.1e-19 68.2 3.9 8.7e-19 67.1 3.9 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KXS99173.1 - 0.019 14.9 0.3 0.043 13.7 0.3 1.6 1 0 0 1 1 1 0 Homeobox KN domain UCH PF00443.29 KXS99174.1 - 3e-29 102.3 0.1 4e-29 101.9 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXS99174.1 - 1e-13 51.6 1.0 2.6e-13 50.3 1.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Sugar_tr PF00083.24 KXS99175.1 - 2.1e-76 257.6 20.4 3.8e-76 256.8 20.4 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter PAP2_3 PF14378.6 KXS99175.1 - 3.3e-32 111.7 13.9 3.3e-32 111.7 13.9 4.2 3 1 0 3 3 3 1 PAP2 superfamily MFS_1 PF07690.16 KXS99175.1 - 4.1e-19 68.7 5.3 4.1e-19 68.7 5.3 4.0 3 1 0 3 3 3 2 Major Facilitator Superfamily PAP2 PF01569.21 KXS99175.1 - 0.0064 16.3 2.2 0.0064 16.3 2.2 3.6 3 1 0 3 3 3 1 PAP2 superfamily Vps55 PF04133.14 KXS99176.1 - 5.3e-42 142.5 8.6 6.1e-42 142.3 8.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 EI24 PF07264.11 KXS99176.1 - 0.016 15.4 6.0 0.016 15.4 6.0 1.4 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DUF4231 PF14015.6 KXS99176.1 - 0.089 13.3 2.8 0.34 11.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF4349 PF14257.6 KXS99176.1 - 0.13 11.7 0.5 0.26 10.7 0.0 1.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4349) ABC2_membrane_2 PF12679.7 KXS99176.1 - 9.8 5.4 11.1 38 3.4 10.7 2.0 1 1 0 1 1 1 0 ABC-2 family transporter protein Molybdopterin PF00384.22 KXS99177.1 - 6.9e-72 242.7 0.0 2.4e-70 237.6 0.0 2.3 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 KXS99177.1 - 2.2e-21 75.7 0.2 9.2e-21 73.7 0.2 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 KXS99177.1 - 2.8e-17 62.0 0.2 2.8e-17 62.0 0.2 2.1 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region NADH_dhqG_C PF09326.11 KXS99177.1 - 3.7e-16 59.5 0.1 9.6e-16 58.2 0.1 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer2 PF00111.27 KXS99177.1 - 1.4e-08 34.5 0.4 1.4e-08 34.5 0.4 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 KXS99177.1 - 0.0024 17.6 0.0 0.32 10.7 0.0 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Lyx_isomer PF07385.12 KXS99177.1 - 0.034 13.4 0.0 0.066 12.5 0.0 1.4 1 0 0 1 1 1 0 D-lyxose isomerase Fer4_19 PF06902.11 KXS99177.1 - 0.11 12.5 0.2 26 5.0 0.1 2.6 2 0 0 2 2 2 0 Divergent 4Fe-4S mono-cluster Fer4 PF00037.27 KXS99177.1 - 0.13 12.2 1.1 3.5 7.6 0.3 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain MDM10 PF12519.8 KXS99178.1 - 2.1e-142 475.3 5.1 2e-127 425.9 2.9 2.1 1 1 1 2 2 2 2 Mitochondrial distribution and morphology protein 10 Porin_3 PF01459.22 KXS99178.1 - 1.3e-05 24.8 0.0 0.00026 20.6 0.0 2.6 2 1 0 2 2 2 1 Eukaryotic porin DUF4336 PF14234.6 KXS99180.1 - 1.1e-07 31.4 0.0 3.8e-05 23.1 0.0 2.7 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) UCH PF00443.29 KXS99182.1 - 1.5e-24 86.9 0.0 2.5e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXS99182.1 - 5.3e-11 42.7 1.3 1.4e-10 41.2 0.0 2.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Dynein_light PF01221.18 KXS99182.1 - 0.2 12.0 0.1 0.2 12.0 0.1 2.5 3 0 0 3 3 3 0 Dynein light chain type 1 Prim_Zn_Ribbon PF08273.12 KXS99182.1 - 1.2 9.5 6.5 14 6.1 0.4 3.0 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase PRK PF00485.18 KXS99183.1 - 0.012 15.4 0.8 0.03 14.1 0.8 1.6 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family TFIIF_alpha PF05793.12 KXS99184.1 - 0.46 9.0 54.7 0.64 8.6 54.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 KXS99184.1 - 2.7 6.2 24.2 3.7 5.7 24.2 1.3 1 0 0 1 1 1 0 CDC45-like protein BSP_II PF05432.11 KXS99184.1 - 7.5 6.1 39.9 9.7 5.8 39.9 1.0 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) TFIIF_alpha PF05793.12 KXS99185.1 - 0.46 9.0 54.7 0.64 8.6 54.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 KXS99185.1 - 2.7 6.2 24.2 3.7 5.7 24.2 1.3 1 0 0 1 1 1 0 CDC45-like protein BSP_II PF05432.11 KXS99185.1 - 7.5 6.1 39.9 9.7 5.8 39.9 1.0 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) TFIIF_alpha PF05793.12 KXS99187.1 - 0.46 9.0 54.7 0.64 8.6 54.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 KXS99187.1 - 2.7 6.2 24.2 3.7 5.7 24.2 1.3 1 0 0 1 1 1 0 CDC45-like protein BSP_II PF05432.11 KXS99187.1 - 7.5 6.1 39.9 9.7 5.8 39.9 1.0 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) TFIIF_alpha PF05793.12 KXS99188.1 - 0.46 9.0 54.7 0.64 8.6 54.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 KXS99188.1 - 2.7 6.2 24.2 3.7 5.7 24.2 1.3 1 0 0 1 1 1 0 CDC45-like protein BSP_II PF05432.11 KXS99188.1 - 7.5 6.1 39.9 9.7 5.8 39.9 1.0 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) JAB PF01398.21 KXS99189.1 - 1.9e-28 98.8 0.5 3.2e-28 98.1 0.5 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 KXS99189.1 - 3.1e-17 63.3 0.0 6.9e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 KXS99189.1 - 7.8e-06 25.7 0.3 2e-05 24.4 0.0 1.8 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 KXS99189.1 - 0.01 15.9 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) Thiamine_BP PF01910.17 KXS99189.1 - 0.11 12.4 0.3 0.61 10.0 0.1 2.3 1 1 1 2 2 2 0 Thiamine-binding protein UCH PF00443.29 KXS99191.1 - 4.7e-22 78.7 0.1 7.2e-22 78.1 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXS99191.1 - 3.5e-14 53.1 0.7 6.6e-14 52.2 0.7 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase APCDDC PF14921.6 KXS99191.1 - 0.058 12.8 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Adenomatosis polyposis coli down-regulated 1 Peptidase_C54 PF03416.19 KXS99191.1 - 0.096 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase family C54 Glyco_hydro_72 PF03198.14 KXS99192.1 - 2.1e-125 418.1 1.4 2.6e-125 417.9 1.4 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Adap_comp_sub PF00928.21 KXS99194.1 - 9.5e-17 61.2 0.0 1.3e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KXS99194.1 - 5e-07 29.7 0.1 8.6e-07 29.0 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RPM2 PF08579.11 KXS99194.1 - 0.00022 21.6 0.4 0.0052 17.2 0.2 2.3 2 0 0 2 2 2 1 Mitochondrial ribonuclease P subunit (RPM2) Mon1 PF03164.14 KXS99194.1 - 0.015 14.4 0.3 0.021 13.9 0.3 1.2 1 0 0 1 1 1 0 Trafficking protein Mon1 Peptidase_M3 PF01432.20 KXS99195.1 - 1.4e-120 403.6 0.4 1.9e-120 403.2 0.4 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M32 PF02074.15 KXS99195.1 - 0.14 10.9 4.3 0.14 10.9 0.0 2.9 4 0 0 4 4 4 0 Carboxypeptidase Taq (M32) metallopeptidase HSCB_C PF07743.13 KXS99195.1 - 0.14 12.7 2.5 0.59 10.7 0.3 2.9 3 0 0 3 3 3 0 HSCB C-terminal oligomerisation domain Spb1_C PF07780.12 KXS99196.1 - 8.6e-80 267.3 21.9 8.6e-80 267.3 21.9 3.4 3 2 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.19 KXS99196.1 - 5.1e-54 183.1 0.0 8.6e-54 182.3 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 KXS99196.1 - 3.1e-50 170.2 17.0 3.1e-50 170.2 17.0 4.6 4 0 0 4 4 4 1 Domain of unknown function (DUF3381) Methyltr_RsmB-F PF01189.17 KXS99196.1 - 0.042 13.5 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F WHIM1 PF15612.6 KXS99197.1 - 0.082 12.5 0.2 0.16 11.6 0.2 1.5 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 F-box-like_2 PF13013.6 KXS99199.1 - 0.16 11.9 1.7 0.18 11.8 0.4 1.8 2 1 0 2 2 2 0 F-box-like domain DNA_pol_B PF00136.21 KXS99200.1 - 7.1e-145 483.2 1.5 1.1e-144 482.6 1.5 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KXS99200.1 - 9.8e-77 258.3 0.0 1.5e-76 257.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KXS99200.1 - 5.1e-17 62.1 2.6 1.1e-16 61.1 2.6 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 KXS99200.1 - 0.0072 15.2 1.0 0.023 13.6 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.9 KXS99200.1 - 0.015 15.0 0.3 0.049 13.3 0.1 1.9 2 0 0 2 2 2 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB C1_1 PF00130.22 KXS99200.1 - 7.6 6.5 6.0 92 3.0 6.0 2.3 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Mo-co_dimer PF03404.16 KXS99201.1 - 1.3e-60 203.4 0.1 2.3e-60 202.6 0.1 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.19 KXS99201.1 - 2.1e-54 183.7 0.0 4e-54 182.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.24 KXS99201.1 - 6.3e-35 119.5 0.0 1.1e-34 118.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KXS99201.1 - 1.5e-27 96.4 0.0 5.5e-27 94.6 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 KXS99201.1 - 5.9e-20 71.2 0.0 1.4e-19 70.0 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 KXS99201.1 - 0.0012 18.9 0.1 0.011 15.9 0.0 2.2 1 1 1 2 2 2 1 Ferric reductase NAD binding domain SBF_like PF13593.6 KXS99202.1 - 3.9e-81 272.8 25.0 4.5e-81 272.6 25.0 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 KXS99202.1 - 1.7e-13 50.7 9.8 1.7e-13 50.7 9.8 1.9 1 1 1 2 2 2 1 Sodium Bile acid symporter family DUF2207 PF09972.9 KXS99202.1 - 1 8.0 5.5 0.79 8.4 0.1 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF1129 PF06570.11 KXS99202.1 - 1 8.8 12.1 1.2 8.6 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) Astacin PF01400.24 KXS99210.1 - 8.6e-08 32.0 0.0 0.00025 20.7 0.0 2.1 1 1 0 2 2 2 2 Astacin (Peptidase family M12A) Methyltransf_11 PF08241.12 KXS99211.1 - 6.3e-21 74.8 0.0 9.9e-21 74.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS99211.1 - 6.9e-20 71.6 0.0 1.3e-19 70.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS99211.1 - 3.8e-12 46.2 0.0 6.3e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS99211.1 - 2.8e-11 44.0 0.0 4.6e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXS99211.1 - 6.7e-10 38.7 0.0 1e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KXS99211.1 - 5.8e-09 36.0 0.0 7.9e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KXS99211.1 - 0.0028 17.4 0.0 0.0047 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 KXS99211.1 - 0.0083 15.6 0.0 0.038 13.4 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase PrmA PF06325.13 KXS99211.1 - 0.013 14.9 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) tRNA_U5-meth_tr PF05958.11 KXS99211.1 - 0.013 14.5 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase MTS PF05175.14 KXS99211.1 - 0.016 14.8 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain ADH_zinc_N PF00107.26 KXS99211.1 - 0.024 14.6 0.0 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Pox_MCEL PF03291.16 KXS99211.1 - 0.042 13.0 0.0 0.059 12.5 0.0 1.1 1 0 0 1 1 1 0 mRNA capping enzyme Methyltransf_32 PF13679.6 KXS99211.1 - 0.12 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.12 KXS99211.1 - 0.12 11.5 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Mob1_phocein PF03637.17 KXS99212.1 - 9.7e-24 84.3 0.1 1.7e-23 83.5 0.1 1.3 1 0 0 1 1 1 1 Mob1/phocein family DND1_DSRM PF14709.7 KXS99213.1 - 0.084 13.1 0.1 0.89 9.9 0.1 2.1 1 1 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.26 KXS99213.1 - 0.13 13.0 0.1 0.3 11.8 0.1 1.6 1 1 0 1 1 1 0 Double-stranded RNA binding motif Cellulase PF00150.18 KXS99215.1 - 3e-15 56.4 0.8 6.5e-15 55.3 0.8 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) ANAPC1 PF12859.7 KXS99216.1 - 0.078 13.5 0.0 0.085 13.4 0.0 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 zf-NOSIP PF15906.5 KXS99216.1 - 0.16 12.1 0.0 0.18 11.9 0.0 1.1 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein Dak1 PF02733.17 KXS99217.1 - 1.6e-90 303.2 0.0 1.8e-90 303.0 0.0 1.0 1 0 0 1 1 1 1 Dak1 domain PAS_3 PF08447.12 KXS99218.1 - 2.9e-09 37.1 0.0 3.8e-08 33.5 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 KXS99218.1 - 8.3e-07 29.2 0.0 1.2e-05 25.5 0.0 2.2 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 KXS99218.1 - 4.1e-05 23.8 0.0 0.046 14.0 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 KXS99218.1 - 0.00047 20.1 0.0 0.025 14.6 0.0 2.4 2 0 0 2 2 2 1 PAS fold PAS_11 PF14598.6 KXS99218.1 - 0.0045 17.1 0.0 0.017 15.3 0.0 1.9 2 0 0 2 2 2 1 PAS domain Fungal_trans PF04082.18 KXS99219.1 - 1.9e-07 30.4 1.2 4.3e-07 29.2 1.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF4396 PF14342.6 KXS99221.1 - 2.4e-38 131.7 15.5 2.4e-38 131.7 15.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4396) Cys_knot PF00007.22 KXS99221.1 - 0.13 12.6 1.2 0.19 12.1 1.2 1.2 1 0 0 1 1 1 0 Cystine-knot domain ECM11 PF15463.6 KXS99222.1 - 8.6e-36 123.4 0.6 8.6e-36 123.4 0.6 2.5 3 0 0 3 3 3 1 Extracellular mutant protein 11 EMC3_TMCO1 PF01956.16 KXS99223.1 - 0.082 12.6 0.9 0.098 12.4 0.9 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like ALMT PF11744.8 KXS99223.1 - 0.082 11.7 0.9 0.091 11.6 0.9 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Glyco_hydro_2_C PF02836.17 KXS99224.1 - 4e-111 370.9 0.0 5.4e-111 370.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 KXS99224.1 - 3.7e-62 210.1 0.0 7e-62 209.2 0.0 1.4 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 KXS99224.1 - 1e-47 162.2 0.1 2.2e-47 161.1 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 KXS99224.1 - 3.3e-19 69.2 0.0 9.2e-19 67.7 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 KXS99224.1 - 3e-16 60.0 0.0 9.4e-16 58.5 0.0 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 KXS99224.1 - 0.00082 19.9 0.7 0.0042 17.6 0.2 2.5 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain Xan_ur_permease PF00860.20 KXS99225.1 - 5.5e-65 219.6 34.4 1.1e-63 215.3 34.4 2.0 1 1 0 1 1 1 1 Permease family DUF2237 PF09996.9 KXS99226.1 - 1.3e-39 134.8 0.0 2.4e-39 133.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) Abhydrolase_6 PF12697.7 KXS99226.1 - 3.2e-08 34.4 0.6 9.1e-08 33.0 0.6 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXS99226.1 - 3.1e-07 30.3 0.1 1e-06 28.6 0.1 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXS99226.1 - 4.4e-06 26.1 0.0 7.3e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Glyco_hydro_106 PF17132.4 KXS99227.1 - 2.1e-25 89.2 0.0 6.3e-25 87.6 0.0 1.7 2 1 0 2 2 2 1 alpha-L-rhamnosidase DUF846 PF05832.12 KXS99228.1 - 1.5e-51 174.1 7.5 1.7e-51 173.9 7.5 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) TMEM220 PF15071.6 KXS99228.1 - 0.023 15.4 1.0 0.044 14.6 0.1 1.9 2 0 0 2 2 2 0 Transmembrane family 220, helix TctB PF07331.11 KXS99228.1 - 0.044 14.1 10.9 0.62 10.3 3.5 2.2 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family Methyltransf_2 PF00891.18 KXS99229.1 - 4.7e-16 58.7 0.1 6.6e-16 58.2 0.1 1.2 1 0 0 1 1 1 1 O-methyltransferase domain HTH_IclR PF09339.10 KXS99229.1 - 0.0022 17.8 0.0 0.0052 16.6 0.0 1.7 1 0 0 1 1 1 1 IclR helix-turn-helix domain TrmB PF01978.19 KXS99229.1 - 0.031 14.2 0.0 0.065 13.1 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB MCM3AP_GANP PF16769.5 KXS99229.1 - 0.039 12.2 0.0 0.058 11.7 0.0 1.1 1 0 0 1 1 1 0 MCM3AP domain of GANP Amidase PF01425.21 KXS99230.1 - 8.4e-85 285.4 0.0 1.1e-84 285.0 0.0 1.1 1 0 0 1 1 1 1 Amidase Sugar_tr PF00083.24 KXS99231.1 - 7.4e-77 259.1 18.8 8.6e-77 258.9 18.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS99231.1 - 2.4e-25 89.2 21.8 2.4e-25 89.2 21.8 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 KXS99231.1 - 9.1e-06 24.5 12.0 0.0013 17.4 1.3 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.13 KXS99231.1 - 0.00025 19.6 0.8 0.00035 19.1 0.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXS99232.1 - 6.6e-71 239.5 19.4 1.4e-69 235.1 19.4 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS99232.1 - 1.2e-23 83.6 17.2 1.2e-23 83.6 17.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXS99232.1 - 2.5e-05 23.0 13.5 0.0014 17.3 1.3 2.5 2 1 0 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.13 KXS99232.1 - 0.00026 19.6 0.8 0.00037 19.0 0.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXS99233.1 - 2.2e-94 316.9 19.5 2.8e-94 316.6 19.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS99233.1 - 6.7e-31 107.5 20.2 9.9e-31 106.9 20.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3792 PF12670.7 KXS99233.1 - 3.2 7.9 10.2 9.9 6.4 1.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) SAD_SRA PF02182.17 KXS99234.1 - 1.4e-15 57.4 0.0 2.9e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 SAD/SRA domain Aminotran_1_2 PF00155.21 KXS99235.1 - 2.1e-84 283.8 0.0 2.5e-84 283.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Peptidase_M20 PF01546.28 KXS99237.1 - 3.7e-18 66.0 0.1 5.6e-18 65.4 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 KXS99237.1 - 0.0045 16.7 0.0 0.0078 15.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 F-box-like PF12937.7 KXS99238.1 - 5.8e-07 29.3 1.7 8.1e-07 28.8 0.2 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXS99238.1 - 3.8e-05 23.5 0.1 9.3e-05 22.2 0.1 1.6 1 0 0 1 1 1 1 F-box domain zf-H2C2_2 PF13465.6 KXS99239.1 - 1.4e-09 37.9 15.7 7.5e-05 23.0 3.3 3.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KXS99239.1 - 2.8e-08 33.8 14.0 0.00058 20.2 4.5 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXS99239.1 - 0.00013 22.5 11.3 0.066 14.1 3.1 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXS99239.1 - 0.016 15.5 0.4 0.068 13.5 0.4 2.1 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KXS99239.1 - 0.064 13.3 1.2 3 8.0 0.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger FOXP-CC PF16159.5 KXS99239.1 - 0.28 11.8 0.1 0.28 11.8 0.1 3.5 3 1 1 4 4 4 0 FOXP coiled-coil domain WD40 PF00400.32 KXS99240.1 - 2.1e-14 53.7 3.7 1.4e-06 28.9 0.0 4.5 5 0 0 5 5 5 2 WD domain, G-beta repeat cobW PF02492.19 KXS99241.1 - 8.9e-49 165.5 0.1 1.3e-48 164.9 0.1 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KXS99241.1 - 2.9e-06 27.1 0.1 5.5e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 KXS99241.1 - 3.3e-05 23.9 0.4 0.29 11.0 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 KXS99241.1 - 0.00069 20.2 0.1 0.0013 19.2 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXS99241.1 - 0.0025 18.2 0.0 0.0068 16.8 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KXS99241.1 - 0.0077 16.0 0.3 0.019 14.7 0.0 1.7 2 0 0 2 2 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 KXS99241.1 - 0.014 15.1 0.3 0.072 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 KXS99241.1 - 0.017 14.1 0.2 1.4 7.8 0.0 2.9 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 KXS99241.1 - 0.02 15.0 0.0 0.034 14.2 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 KXS99241.1 - 0.023 14.5 0.3 0.31 10.8 0.3 2.1 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 KXS99241.1 - 0.029 14.9 0.0 0.077 13.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter GTP_EFTU PF00009.27 KXS99241.1 - 0.034 13.7 0.0 6.6 6.2 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 KXS99241.1 - 0.036 14.6 0.0 0.12 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KXS99241.1 - 0.041 13.9 0.1 0.093 12.7 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 KXS99241.1 - 0.049 13.6 0.0 0.079 12.9 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KXS99241.1 - 0.059 13.6 0.2 0.16 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF2791 PF10923.8 KXS99241.1 - 0.094 11.5 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) Septin PF00735.18 KXS99241.1 - 0.11 11.7 0.2 7.8 5.7 0.0 2.2 2 0 0 2 2 2 0 Septin WD40 PF00400.32 KXS99242.1 - 2.1e-14 53.7 3.7 1.4e-06 28.9 0.0 4.5 5 0 0 5 5 5 2 WD domain, G-beta repeat Peptidase_S9 PF00326.21 KXS99243.1 - 1.2e-48 165.4 1.8 7e-31 107.4 0.3 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Pkinase PF00069.25 KXS99243.1 - 3.2e-33 115.2 0.0 1.3e-18 67.4 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXS99243.1 - 1e-12 47.9 0.0 1.1e-11 44.6 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Esterase PF00756.20 KXS99243.1 - 4.1e-05 23.4 1.5 0.0001 22.1 1.5 1.6 1 0 0 1 1 1 1 Putative esterase APH PF01636.23 KXS99243.1 - 0.00012 22.1 0.1 0.00031 20.7 0.1 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family PD40 PF07676.12 KXS99243.1 - 0.02 14.8 0.2 3.2 7.8 0.0 3.6 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Peptidase_S15 PF02129.18 KXS99243.1 - 0.021 14.4 11.3 0.016 14.8 1.0 2.6 3 0 0 3 3 3 0 X-Pro dipeptidyl-peptidase (S15 family) FXR_C1 PF16096.5 KXS99243.1 - 0.059 13.6 3.1 0.14 12.4 3.1 1.6 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 DUF2920 PF11144.8 KXS99243.1 - 0.1 11.7 0.0 0.35 10.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) Methyltr_RsmB-F PF01189.17 KXS99251.1 - 1.8e-35 122.4 0.0 6.8e-28 97.7 0.0 3.4 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KXS99251.1 - 0.03 14.4 0.0 0.058 13.5 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Tyr_Deacylase PF02580.16 KXS99253.1 - 1.8e-54 184.2 0.0 2.1e-54 184.0 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase DUF1958 PF09211.10 KXS99253.1 - 0.073 13.4 0.1 0.31 11.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1958) PRiA4_ORF3 PF07929.11 KXS99254.1 - 1.6e-34 119.1 0.0 3.6e-34 118.0 0.0 1.4 1 1 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein zf-MYND PF01753.18 KXS99254.1 - 4.1e-10 39.6 12.5 7.2e-10 38.8 12.5 1.4 1 0 0 1 1 1 1 MYND finger XTBD PF11952.8 KXS99254.1 - 0.13 12.1 0.1 0.67 9.8 0.0 2.0 2 0 0 2 2 2 0 XRN-Two Binding Domain, XTBD Arylsulfotran_N PF17425.2 KXS99254.1 - 0.19 11.8 0.0 0.38 10.8 0.0 1.4 1 0 0 1 1 1 0 Arylsulfotransferase Ig-like domain zf-C6H2 PF15801.5 KXS99254.1 - 0.25 11.7 9.1 1 9.7 9.1 2.0 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding UQ_con PF00179.26 KXS99255.1 - 1.8e-11 43.8 0.1 3.9e-11 42.8 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KXS99255.1 - 0.013 15.8 0.1 0.027 14.8 0.1 1.5 1 0 0 1 1 1 0 RWD domain TRP PF06011.12 KXS99256.1 - 3.2e-167 556.6 29.2 3.9e-167 556.3 29.2 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KXS99256.1 - 1.9e-42 144.9 1.9 3.2e-42 144.2 1.9 1.4 1 0 0 1 1 1 1 ML-like domain Ac76 PF05814.11 KXS99256.1 - 1.1 9.3 0.0 1.1 9.3 0.0 4.1 5 0 0 5 5 5 0 Orf76 (Ac76) Shisa PF13908.6 KXS99256.1 - 1.3 9.2 4.7 3.8 7.7 0.1 3.2 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator DEAD PF00270.29 KXS99257.1 - 2.8e-33 115.1 0.0 7.6e-32 110.5 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXS99257.1 - 1.8e-23 83.0 0.0 4e-23 81.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KXS99257.1 - 2.1e-16 59.9 0.0 5.3e-16 58.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KXS99257.1 - 1e-06 28.9 0.0 2.4e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KXS99257.1 - 0.06 12.6 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase RcsF PF16358.5 KXS99258.1 - 0.012 15.6 0.8 0.047 13.8 0.2 2.2 2 1 1 3 3 3 0 RcsF lipoprotein RRP7 PF12923.7 KXS99258.1 - 0.12 12.5 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Proteasome PF00227.26 KXS99259.1 - 1.8e-50 171.1 0.1 2.3e-50 170.7 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit ADH_zinc_N PF00107.26 KXS99260.1 - 1.7e-16 60.4 0.0 2.9e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXS99260.1 - 2.8e-13 51.0 0.0 7.2e-13 49.7 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXS99260.1 - 4.5e-08 32.9 0.1 7.8e-06 25.7 0.0 2.4 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain Kinesin PF00225.23 KXS99261.1 - 2.4e-114 381.7 0.6 2.4e-114 381.7 0.6 2.5 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KXS99261.1 - 9.9e-30 103.4 4.0 6.6e-29 100.8 0.5 3.0 2 0 0 2 2 2 1 Microtubule binding FlgH PF02107.16 KXS99261.1 - 0.03 13.9 1.1 0.14 11.7 0.0 2.7 3 0 0 3 3 3 0 Flagellar L-ring protein zf-C2H2 PF00096.26 KXS99264.1 - 0.0049 17.3 4.8 1.4 9.5 0.2 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KXS99264.1 - 0.01 15.5 4.0 0.29 10.9 0.1 3.0 2 0 0 2 2 2 0 C2H2-type zinc-finger domain FOXP-CC PF16159.5 KXS99264.1 - 0.039 14.6 0.8 0.19 12.4 0.5 2.0 1 1 1 2 2 2 0 FOXP coiled-coil domain MAP65_ASE1 PF03999.12 KXS99264.1 - 0.32 9.6 1.9 0.3 9.7 1.9 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) NAD_binding_8 PF13450.6 KXS99265.1 - 3.4e-12 46.4 0.0 9.3e-12 45.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 KXS99265.1 - 3.8e-12 45.4 2.2 3e-11 42.5 0.1 2.6 3 1 0 3 3 3 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KXS99265.1 - 1.2e-05 24.6 0.1 0.00014 21.1 0.0 2.6 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KXS99265.1 - 0.0014 17.9 0.0 0.016 14.5 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXS99265.1 - 0.0032 16.8 0.0 0.049 12.9 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase BTRD1 PF17660.1 KXS99265.1 - 0.12 12.3 0.3 0.26 11.2 0.3 1.6 1 0 0 1 1 1 0 Bacterial tandem repeat domain 1 BIR PF00653.21 KXS99266.1 - 1.5e-44 150.5 7.1 3.1e-23 82.2 0.2 2.5 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain Ccdc124 PF06244.12 KXS99267.1 - 2.1e-26 93.0 22.5 2.1e-26 93.0 22.5 2.3 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 Pkinase PF00069.25 KXS99268.1 - 2.9e-15 56.4 0.0 1.8e-14 53.8 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXS99268.1 - 1.6e-07 30.9 0.1 3.9e-07 29.6 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase dsrm PF00035.26 KXS99268.1 - 0.00021 21.9 0.0 0.15 12.8 0.0 2.9 2 0 0 2 2 2 2 Double-stranded RNA binding motif Dicer_dimer PF03368.14 KXS99268.1 - 0.044 13.9 0.2 0.29 11.3 0.0 2.4 2 0 0 2 2 2 0 Dicer dimerisation domain tRNA-synt_2b PF00587.25 KXS99270.1 - 2.2e-22 79.9 0.0 1.5e-21 77.2 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KXS99270.1 - 1.1e-14 54.5 1.8 2.3e-14 53.5 1.8 1.6 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain CENP-F_leu_zip PF10473.9 KXS99270.1 - 2.5 8.1 13.5 11 6.1 0.0 3.9 3 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Thiolase_N PF00108.23 KXS99271.1 - 1.7e-88 296.3 1.0 3.1e-88 295.5 1.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXS99271.1 - 6.1e-38 129.2 0.9 6.1e-38 129.2 0.9 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KXS99271.1 - 0.00034 20.3 2.6 0.007 16.0 1.1 2.4 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KXS99271.1 - 0.032 14.1 3.2 0.28 11.1 0.0 2.8 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FMO-like PF00743.19 KXS99272.1 - 1.2e-18 66.9 0.1 1.3e-16 60.2 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXS99272.1 - 5.7e-16 58.7 0.0 1.6e-12 47.3 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXS99272.1 - 7.6e-16 58.2 0.0 6e-13 48.7 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXS99272.1 - 1.7e-13 50.4 0.0 1.9e-11 43.7 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KXS99272.1 - 2.4e-10 40.5 0.0 2.8e-06 27.5 0.0 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KXS99272.1 - 8e-08 32.4 0.1 0.1 12.6 0.1 4.2 3 1 0 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.24 KXS99272.1 - 1.2e-07 31.6 2.2 0.023 14.3 0.2 3.6 3 1 1 4 4 4 3 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 KXS99272.1 - 7.8e-06 26.3 0.0 0.23 11.9 0.0 3.2 2 1 0 2 2 2 2 Putative NAD(P)-binding Pyr_redox PF00070.27 KXS99272.1 - 0.00011 22.7 0.9 0.83 10.3 1.1 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXS99272.1 - 0.00027 19.8 1.4 1.4 7.5 0.1 3.2 3 0 0 3 3 3 2 HI0933-like protein Thi4 PF01946.17 KXS99272.1 - 0.0004 19.7 1.4 0.042 13.1 0.2 2.5 3 0 0 3 3 3 1 Thi4 family Shikimate_DH PF01488.20 KXS99272.1 - 0.00048 20.2 0.0 0.023 14.8 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 KXS99272.1 - 0.0011 18.1 1.8 0.019 14.1 0.1 2.5 3 0 0 3 3 3 1 FAD binding domain GIDA PF01134.22 KXS99272.1 - 0.0024 17.1 1.2 3.5 6.6 0.0 3.4 4 0 0 4 4 4 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KXS99272.1 - 0.003 16.7 0.5 0.75 8.8 0.2 3.3 4 0 0 4 4 4 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 KXS99272.1 - 0.016 14.5 0.4 0.13 11.5 0.2 2.4 3 0 0 3 3 3 0 FAD binding domain FAD_oxidored PF12831.7 KXS99272.1 - 0.073 12.4 3.1 0.061 12.7 0.5 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KXS99272.1 - 0.12 11.7 0.7 1.3 8.3 0.0 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 KXS99272.1 - 0.13 11.5 0.0 26 3.9 0.0 3.0 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Het-C PF07217.11 KXS99274.1 - 1.1e-245 816.4 0.0 1.6e-245 816.0 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Zn_dep_PLPC PF00882.18 KXS99274.1 - 0.056 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Zinc dependent phospholipase C DUF3246 PF11596.8 KXS99274.1 - 0.12 11.8 0.8 0.29 10.5 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Med19 PF10278.9 KXS99274.1 - 1.5 8.7 18.3 4.3 7.2 18.0 2.0 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Gly_kinase PF02595.15 KXS99275.1 - 6.4e-131 436.7 5.6 7.3e-131 436.5 5.6 1.0 1 0 0 1 1 1 1 Glycerate kinase family DUF2373 PF10180.9 KXS99276.1 - 4e-24 84.2 0.6 7.9e-24 83.3 0.6 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) NAM-associated PF14303.6 KXS99276.1 - 0.00011 22.9 12.3 0.00011 22.9 12.3 3.9 2 1 1 3 3 3 1 No apical meristem-associated C-terminal domain AF-4 PF05110.13 KXS99276.1 - 0.0024 16.0 24.7 0.0024 16.0 24.7 2.3 2 0 0 2 2 2 1 AF-4 proto-oncoprotein MFS_1 PF07690.16 KXS99277.1 - 1.1e-27 96.9 28.1 8.2e-23 80.9 7.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS99277.1 - 4.8e-07 29.0 5.8 4.8e-07 29.0 5.8 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter TMEM171 PF15471.6 KXS99277.1 - 0.028 13.4 0.7 0.072 12.1 0.7 1.6 1 0 0 1 1 1 0 Transmembrane protein family 171 MFS_1_like PF12832.7 KXS99277.1 - 0.047 12.5 6.4 1.1 8.0 1.3 3.1 3 1 1 4 4 4 0 MFS_1 like family Spore_YhaL PF14147.6 KXS99277.1 - 0.051 13.3 0.1 0.28 10.9 0.0 2.2 2 0 0 2 2 2 0 Sporulation protein YhaL vATP-synt_AC39 PF01992.16 KXS99278.1 - 6.5e-106 354.6 0.0 7.2e-106 354.5 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Not3 PF04065.15 KXS99279.1 - 3.5e-90 301.5 26.7 6e-90 300.7 26.7 1.4 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 KXS99279.1 - 1.6e-43 147.9 11.8 4.2e-43 146.6 11.8 1.7 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Syntaxin_2 PF14523.6 KXS99279.1 - 0.018 15.4 3.3 0.018 15.4 3.3 2.3 2 0 0 2 2 2 0 Syntaxin-like protein DUF2373 PF10180.9 KXS99279.1 - 0.028 14.2 3.6 0.064 13.1 3.6 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) DUF2524 PF10732.9 KXS99279.1 - 0.052 13.9 0.9 0.17 12.2 0.9 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) CorA PF01544.18 KXS99279.1 - 0.074 12.3 1.0 0.15 11.4 1.0 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Cep57_MT_bd PF06657.13 KXS99279.1 - 0.14 12.6 11.0 2.6 8.5 1.4 2.8 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 FlaC_arch PF05377.11 KXS99279.1 - 0.26 11.7 6.3 1.1 9.7 0.0 3.8 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) ING PF12998.7 KXS99279.1 - 2.9 8.5 14.6 0.33 11.6 2.0 3.1 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Tam41_Mmp37 PF09139.11 KXS99280.1 - 3.6e-124 414.4 0.0 5.3e-124 413.9 0.0 1.2 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial AP3D1 PF06375.11 KXS99280.1 - 1.6 8.9 14.6 4.1 7.6 2.1 2.3 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 SR-25 PF10500.9 KXS99280.1 - 6.2 6.4 38.6 0.13 11.8 20.9 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Peroxidase_2 PF01328.17 KXS99281.1 - 1.1e-39 137.0 0.0 1.9e-39 136.2 0.0 1.4 1 0 0 1 1 1 1 Peroxidase, family 2 Patatin PF01734.22 KXS99282.1 - 9.4e-19 68.4 0.4 2.8e-18 66.9 0.4 1.9 1 1 0 1 1 1 1 Patatin-like phospholipase MMR_HSR1 PF01926.23 KXS99282.1 - 0.001 19.1 0.0 0.0021 18.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 KXS99282.1 - 0.084 13.4 0.0 0.3 11.6 0.0 1.9 1 0 0 1 1 1 0 ABC transporter zf-RING_UBOX PF13445.6 KXS99282.1 - 9.3 6.4 20.1 0.4 10.7 12.7 2.6 2 1 0 2 2 2 0 RING-type zinc-finger ABC2_membrane PF01061.24 KXS99283.1 - 2.2e-84 282.1 58.4 6.6e-45 153.1 21.1 3.5 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 KXS99283.1 - 1.3e-34 119.6 0.0 3.5e-17 63.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KXS99283.1 - 3.8e-27 94.0 0.1 3.8e-27 94.0 0.1 3.6 4 0 0 4 4 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KXS99283.1 - 1e-17 64.5 2.6 4.3e-17 62.5 2.6 2.2 1 1 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KXS99283.1 - 1.2e-06 29.1 0.1 0.0022 18.4 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KXS99283.1 - 7.8e-06 25.9 0.2 0.0004 20.3 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase ABC2_membrane_3 PF12698.7 KXS99283.1 - 1e-05 24.8 13.6 1e-05 24.8 13.6 3.1 4 0 0 4 4 4 1 ABC-2 family transporter protein AAA_21 PF13304.6 KXS99283.1 - 2.8e-05 24.1 0.1 0.046 13.5 0.0 2.7 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 KXS99283.1 - 0.00066 19.9 0.0 0.018 15.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KXS99283.1 - 0.0007 19.9 0.0 0.0017 18.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXS99283.1 - 0.001 19.6 0.0 0.029 14.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KXS99283.1 - 0.0011 19.0 0.3 0.1 12.7 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KXS99283.1 - 0.0034 17.7 0.1 0.2 12.0 0.1 3.0 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 KXS99283.1 - 0.0048 16.6 0.1 0.4 10.5 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 KXS99283.1 - 0.0066 15.9 0.6 0.13 11.7 0.1 2.7 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain cobW PF02492.19 KXS99283.1 - 0.0077 15.8 0.1 0.034 13.8 0.0 2.0 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 KXS99283.1 - 0.0086 15.7 0.0 0.091 12.3 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 KXS99283.1 - 0.023 14.4 0.7 0.46 10.2 0.1 3.0 3 0 0 3 3 3 0 AAA domain TsaE PF02367.17 KXS99283.1 - 0.06 13.4 0.2 0.61 10.1 0.2 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Septin PF00735.18 KXS99283.1 - 0.065 12.5 0.5 0.51 9.6 0.1 2.2 2 0 0 2 2 2 0 Septin AAA_30 PF13604.6 KXS99283.1 - 0.066 12.9 0.4 1.7 8.3 0.4 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KXS99283.1 - 0.093 12.6 0.5 0.35 10.8 0.3 2.0 2 0 0 2 2 2 0 NACHT domain GBP PF02263.19 KXS99283.1 - 0.1 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain AAA_23 PF13476.6 KXS99283.1 - 2.1 8.8 6.0 9.5 6.7 0.1 3.4 3 0 0 3 3 3 0 AAA domain ADH_N PF08240.12 KXS99284.1 - 6.7e-23 80.7 1.0 1.2e-22 79.9 1.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXS99284.1 - 2.6e-13 50.1 0.0 4.8e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KXS99284.1 - 0.00013 21.4 0.1 0.0002 20.7 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KXS99284.1 - 0.0057 16.0 0.1 0.0089 15.3 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KXS99284.1 - 0.027 14.3 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IGFBP PF00219.18 KXS99284.1 - 0.029 15.0 0.9 0.054 14.2 0.9 1.4 1 0 0 1 1 1 0 Insulin-like growth factor binding protein hNIFK_binding PF12196.8 KXS99285.1 - 0.099 12.1 0.1 0.28 10.7 0.0 1.8 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK TPT PF03151.16 KXS99287.1 - 7e-33 114.2 22.3 8.4e-33 114.0 22.3 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KXS99287.1 - 2.3e-11 43.5 24.0 3e-11 43.1 24.0 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KXS99287.1 - 0.014 15.5 15.1 0.014 15.5 15.1 2.3 2 0 0 2 2 2 0 EamA-like transporter family Aft1_HRR PF11787.8 KXS99288.1 - 2.3e-23 83.1 7.6 2.3e-23 83.1 7.6 4.0 4 2 0 4 4 4 1 Aft1 HRR domain Aft1_HRA PF11786.8 KXS99288.1 - 6.5e-21 74.5 9.4 6.5e-21 74.5 9.4 2.6 2 1 1 3 3 3 1 Aft1 HRA domain bZIP_1 PF00170.21 KXS99288.1 - 3.8e-13 49.3 3.4 6.1e-13 48.7 3.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor Aft1_OSA PF11785.8 KXS99288.1 - 2.5e-10 40.6 9.0 2.5e-10 40.6 9.0 4.4 4 1 1 5 5 5 2 Aft1 osmotic stress response (OSM) domain bZIP_2 PF07716.15 KXS99288.1 - 1.7e-05 24.8 6.0 3e-05 24.0 6.0 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KXS99288.1 - 0.0016 18.9 2.0 0.0041 17.6 2.0 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor Nnf1 PF03980.14 KXS99288.1 - 0.058 13.8 0.3 0.12 12.8 0.3 1.5 1 0 0 1 1 1 0 Nnf1 Aft1_HRR PF11787.8 KXS99289.1 - 2.3e-23 83.1 7.6 2.3e-23 83.1 7.6 4.0 4 2 0 4 4 4 1 Aft1 HRR domain Aft1_HRA PF11786.8 KXS99289.1 - 6.5e-21 74.5 9.4 6.5e-21 74.5 9.4 2.6 2 1 1 3 3 3 1 Aft1 HRA domain bZIP_1 PF00170.21 KXS99289.1 - 3.8e-13 49.3 3.4 6.1e-13 48.7 3.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor Aft1_OSA PF11785.8 KXS99289.1 - 2.5e-10 40.6 9.0 2.5e-10 40.6 9.0 4.4 4 1 1 5 5 5 2 Aft1 osmotic stress response (OSM) domain bZIP_2 PF07716.15 KXS99289.1 - 1.7e-05 24.8 6.0 3e-05 24.0 6.0 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KXS99289.1 - 0.0016 18.9 2.0 0.0041 17.6 2.0 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor Nnf1 PF03980.14 KXS99289.1 - 0.058 13.8 0.3 0.12 12.8 0.3 1.5 1 0 0 1 1 1 0 Nnf1 Aft1_HRR PF11787.8 KXS99290.1 - 2.5e-23 83.0 7.6 2.5e-23 83.0 7.6 4.1 4 2 0 4 4 4 1 Aft1 HRR domain Aft1_HRA PF11786.8 KXS99290.1 - 7.7e-21 74.2 9.5 7.7e-21 74.2 9.5 2.8 2 1 1 3 3 3 1 Aft1 HRA domain bZIP_1 PF00170.21 KXS99290.1 - 4e-13 49.3 3.4 6.4e-13 48.6 3.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor Aft1_OSA PF11785.8 KXS99290.1 - 2.6e-10 40.6 9.0 2.6e-10 40.6 9.0 4.4 4 1 1 5 5 5 2 Aft1 osmotic stress response (OSM) domain bZIP_2 PF07716.15 KXS99290.1 - 1.9e-05 24.7 6.0 3.1e-05 23.9 6.0 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KXS99290.1 - 0.0018 18.8 2.0 0.0043 17.5 2.0 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor Nnf1 PF03980.14 KXS99290.1 - 0.062 13.7 0.3 0.12 12.7 0.3 1.5 1 0 0 1 1 1 0 Nnf1 GCP_C_terminal PF04130.13 KXS99291.1 - 4.8e-98 328.4 0.2 1.2e-97 327.1 0.2 1.7 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KXS99291.1 - 3.4e-81 273.2 0.0 3.7e-80 269.8 0.0 2.2 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal Sugar_tr PF00083.24 KXS99294.1 - 1.4e-123 413.2 23.0 1.8e-123 412.8 23.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Peptidase_C78 PF07910.13 KXS99294.1 - 5.6e-47 160.0 0.0 9.4e-47 159.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C78 MFS_1 PF07690.16 KXS99294.1 - 1.1e-18 67.3 24.9 1.1e-18 67.3 24.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-Di19 PF05605.12 KXS99294.1 - 0.32 11.3 1.4 0.81 10.0 0.1 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Pex14_N PF04695.13 KXS99294.1 - 1.5 9.5 4.7 0.56 10.8 0.4 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Cation_ATPase_C PF00689.21 KXS99294.1 - 2.3 7.9 17.8 0.11 12.2 5.0 3.5 4 0 0 4 4 4 0 Cation transporting ATPase, C-terminus UPF0029 PF01205.19 KXS99295.1 - 2.9e-38 130.4 0.1 1.3e-36 125.1 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 RWD PF05773.22 KXS99295.1 - 5.7e-06 26.6 0.0 5.2e-05 23.5 0.0 2.1 1 1 0 1 1 1 1 RWD domain Pho88 PF10032.9 KXS99296.1 - 5.8e-84 279.9 0.1 6.5e-84 279.7 0.1 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) DUF4408 PF14364.6 KXS99296.1 - 0.45 10.3 0.2 0.45 10.3 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4408) Glyco_transf_21 PF13506.6 KXS99298.1 - 4.1e-18 65.4 0.5 6.4e-09 35.5 0.5 3.0 2 1 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KXS99298.1 - 5.4e-05 23.1 0.0 0.00018 21.4 0.0 1.9 2 1 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KXS99298.1 - 0.00024 21.1 0.0 0.00088 19.2 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 NMT1 PF09084.11 KXS99299.1 - 0.0012 18.8 0.0 0.0027 17.7 0.0 1.6 1 0 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.7 KXS99299.1 - 0.0032 17.1 0.0 0.0048 16.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1_3 PF16868.5 KXS99299.1 - 0.023 14.1 0.1 0.086 12.2 0.0 1.8 2 0 0 2 2 2 0 NMT1-like family SBP_bac_3 PF00497.20 KXS99299.1 - 0.071 12.5 0.0 0.3 10.5 0.0 1.9 1 1 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 FixP_N PF14715.6 KXS99299.1 - 0.094 12.5 0.5 0.16 11.7 0.5 1.4 1 0 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP NMT1 PF09084.11 KXS99300.1 - 0.0012 18.8 0.0 0.0027 17.7 0.0 1.6 1 0 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.7 KXS99300.1 - 0.0032 17.1 0.0 0.0048 16.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1_3 PF16868.5 KXS99300.1 - 0.023 14.1 0.1 0.086 12.2 0.0 1.8 2 0 0 2 2 2 0 NMT1-like family SBP_bac_3 PF00497.20 KXS99300.1 - 0.071 12.5 0.0 0.3 10.5 0.0 1.9 1 1 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 FixP_N PF14715.6 KXS99300.1 - 0.094 12.5 0.5 0.16 11.7 0.5 1.4 1 0 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP WD40 PF00400.32 KXS99301.1 - 6.1e-24 83.8 13.1 8.1e-05 23.3 0.7 6.5 6 1 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 KXS99301.1 - 7.6e-23 80.5 0.2 2.7e-22 78.8 0.1 2.0 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Frtz PF11768.8 KXS99301.1 - 0.029 12.7 0.0 0.18 10.1 0.0 1.8 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Leader_Erm PF08253.11 KXS99301.1 - 0.36 11.2 1.8 12 6.5 1.0 2.8 2 0 0 2 2 2 0 Erm Leader peptide Rrp15p PF07890.12 KXS99302.1 - 1.4e-39 135.5 10.6 1.4e-39 135.5 10.6 2.2 2 1 0 2 2 2 1 Rrp15p AA_permease_2 PF13520.6 KXS99303.1 - 3.2e-53 181.1 46.4 3.9e-53 180.8 46.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXS99303.1 - 2.5e-23 82.4 37.4 3.5e-23 82.0 37.4 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3493 PF11998.8 KXS99303.1 - 0.24 11.6 0.0 0.24 11.6 0.0 3.1 3 1 1 4 4 4 0 Low psii accumulation1 / Rep27 KASH PF10541.9 KXS99303.1 - 2.8 8.3 5.3 16 5.9 0.3 3.3 3 0 0 3 3 3 0 Nuclear envelope localisation domain FAD-oxidase_C PF02913.19 KXS99304.1 - 3.4e-60 203.8 0.0 5.2e-60 203.2 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KXS99304.1 - 4.1e-37 127.0 0.2 8.7e-36 122.7 0.5 2.3 2 0 0 2 2 2 1 FAD binding domain LemA PF04011.12 KXS99304.1 - 0.13 12.2 0.1 0.32 10.8 0.1 1.7 1 0 0 1 1 1 0 LemA family Nefa_Nip30_N PF10187.9 KXS99304.1 - 0.29 11.5 3.0 0.42 11.0 0.6 2.4 2 1 0 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 SLBB PF10531.9 KXS99305.1 - 0.12 12.3 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 SLBB domain XRN_M PF17846.1 KXS99307.1 - 3.2e-102 342.7 4.9 5e-102 342.1 4.9 1.2 1 0 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 KXS99307.1 - 1.2e-97 326.1 0.0 2.3e-97 325.2 0.0 1.5 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 KXS99307.1 - 4.6e-72 241.8 0.0 4.6e-72 241.8 0.0 1.6 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 KXS99307.1 - 9.1e-30 102.7 0.0 2.2e-29 101.5 0.0 1.7 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 KXS99307.1 - 2e-24 85.5 0.7 4e-24 84.5 0.7 1.6 1 0 0 1 1 1 1 Xrn1 SH3-like domain Xrn1_D3 PF18194.1 KXS99307.1 - 0.00048 20.2 0.0 0.002 18.2 0.0 2.1 2 0 0 2 2 2 1 Exoribonuclease 1 Domain-3 R3H PF01424.22 KXS99307.1 - 0.14 12.2 0.0 0.41 10.7 0.0 1.8 1 0 0 1 1 1 0 R3H domain DER1 PF04511.15 KXS99308.1 - 3.5e-51 173.9 6.0 4e-51 173.7 6.0 1.0 1 0 0 1 1 1 1 Der1-like family SAD_SRA PF02182.17 KXS99310.1 - 6.1e-41 139.7 0.1 8.4e-41 139.3 0.1 1.2 1 0 0 1 1 1 1 SAD/SRA domain tRNA-synt_1b PF00579.25 KXS99311.1 - 1.5e-72 244.4 0.0 2e-72 244.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Proteasome PF00227.26 KXS99312.1 - 6.3e-51 172.6 0.3 8.7e-51 172.1 0.3 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KXS99312.1 - 6.2e-13 48.2 0.3 2.3e-12 46.4 0.1 2.1 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Nsp2a_N PF17896.1 KXS99312.1 - 0.062 12.5 0.0 0.091 11.9 0.0 1.1 1 0 0 1 1 1 0 Replicase polyprotein 1a N-terminal domain Terminase_5 PF06056.12 KXS99312.1 - 0.12 12.3 0.1 0.27 11.1 0.1 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) Ank_4 PF13637.6 KXS99313.1 - 2.3e-10 40.8 0.1 0.00013 22.4 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXS99313.1 - 7.8e-10 39.2 0.1 1.3e-09 38.5 0.1 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KXS99313.1 - 2.4e-07 30.9 0.3 0.00012 22.3 0.2 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KXS99313.1 - 1.6e-05 25.1 0.0 4.3e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS99313.1 - 0.0001 22.5 0.0 0.017 15.6 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat ThiF PF00899.21 KXS99314.1 - 4e-29 101.7 0.0 5.6e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 ThiF family MBOAT PF03062.19 KXS99315.1 - 1.3e-53 182.6 6.5 1.6e-53 182.3 5.7 1.6 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Histone PF00125.24 KXS99315.1 - 2.1e-38 131.7 0.0 3.8e-38 130.8 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KXS99315.1 - 0.0054 16.8 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KXS99315.1 - 0.046 14.1 0.0 0.14 12.5 0.0 1.8 1 0 0 1 1 1 0 CENP-S protein DUF4748 PF15932.5 KXS99316.1 - 3.3e-18 65.2 0.2 4.7e-18 64.7 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4748) PSD1 PF07587.11 KXS99316.1 - 0.032 13.7 0.8 0.036 13.6 0.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1553) DivIC PF04977.15 KXS99316.1 - 0.056 13.2 0.1 0.074 12.8 0.1 1.2 1 0 0 1 1 1 0 Septum formation initiator Nop10p PF04135.12 KXS99317.1 - 1.1e-22 79.8 0.5 1.2e-22 79.6 0.5 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family UDPG_MGDP_dh PF00984.19 KXS99322.1 - 4.8e-24 84.4 0.0 1.4e-23 82.9 0.0 1.8 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_N PF03721.14 KXS99322.1 - 1e-10 41.5 0.1 1.3e-07 31.3 0.0 3.2 1 1 1 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 KXS99322.1 - 0.00014 22.2 0.0 0.0004 20.8 0.0 1.8 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Adenylsucc_synt PF00709.21 KXS99323.1 - 2.5e-170 567.0 0.5 2.8e-170 566.8 0.5 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase LURAP PF14854.6 KXS99324.1 - 0.1 12.6 3.2 0.14 12.2 0.7 2.6 1 1 1 2 2 2 0 Leucine rich adaptor protein Filament PF00038.21 KXS99324.1 - 0.81 9.2 71.2 0.2 11.2 31.6 3.0 1 1 2 3 3 3 0 Intermediate filament protein Epimerase PF01370.21 KXS99325.1 - 7.3e-10 38.7 0.1 1.5e-09 37.6 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXS99325.1 - 1.9e-09 37.7 0.0 2.7e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXS99325.1 - 3.8e-05 23.4 0.4 0.0002 21.0 0.1 1.9 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.19 KXS99325.1 - 0.00034 19.7 0.0 0.0022 17.1 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_2 PF03446.15 KXS99325.1 - 0.0011 19.1 0.0 0.0016 18.6 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase GDP_Man_Dehyd PF16363.5 KXS99325.1 - 0.0073 15.7 0.1 0.055 12.9 0.0 2.1 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase ApbA PF02558.16 KXS99325.1 - 0.02 14.6 0.1 0.046 13.4 0.1 1.7 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 KXS99325.1 - 0.025 14.7 0.0 0.04 14.0 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.15 KXS99325.1 - 0.036 13.2 0.0 0.073 12.2 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein AlaDh_PNT_C PF01262.21 KXS99325.1 - 0.062 12.6 0.0 0.096 12.0 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lipocalin_9 PF17186.4 KXS99325.1 - 0.083 13.2 0.0 0.47 10.7 0.0 2.2 3 0 0 3 3 3 0 Lipocalin-like domain DNA_primase_S PF01896.19 KXS99326.1 - 0.066 13.2 0.0 0.16 12.0 0.0 1.6 1 1 1 2 2 2 0 DNA primase small subunit Macoilin PF09726.9 KXS99331.1 - 9.2 4.7 7.3 10 4.5 7.3 1.1 1 0 0 1 1 1 0 Macoilin family Dynamin_M PF01031.20 KXS99332.1 - 3.5e-100 334.9 0.4 6.2e-100 334.1 0.0 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 KXS99332.1 - 3.5e-57 193.1 0.6 6.7e-57 192.2 0.0 1.8 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 KXS99332.1 - 4.9e-30 103.5 7.8 1.1e-29 102.4 7.8 1.6 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KXS99332.1 - 2.4e-05 24.4 0.6 0.00011 22.2 0.6 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Thioredoxin_14 PF18402.1 KXS99332.1 - 0.08 12.9 0.3 1 9.2 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like domain FeoB_N PF02421.18 KXS99332.1 - 0.085 12.4 0.2 19 4.8 0.0 2.9 3 0 0 3 3 3 0 Ferrous iron transport protein B ERCC3_RAD25_C PF16203.5 KXS99333.1 - 3.7e-119 396.5 1.7 1e-118 395.0 0.9 2.1 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 KXS99333.1 - 7.9e-34 116.5 0.0 1.6e-33 115.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXS99333.1 - 1.9e-17 63.8 1.0 4.5e-17 62.6 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KXS99333.1 - 7.4e-10 39.2 0.5 2.7e-09 37.3 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KXS99333.1 - 3.6e-09 35.8 0.0 8.7e-09 34.5 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 KXS99333.1 - 1.1e-05 25.3 0.0 1.9e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_34 PF13872.6 KXS99333.1 - 0.0011 17.9 0.0 0.0019 17.1 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 SBP_bac_6 PF13343.6 KXS99333.1 - 0.082 12.3 0.0 0.8 9.1 0.0 2.1 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein DUF4820 PF16091.5 KXS99333.1 - 0.39 10.0 4.0 0.85 8.9 4.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) ATP-synt_ab PF00006.25 KXS99334.1 - 7.4e-111 368.9 0.0 1.1e-110 368.4 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 KXS99334.1 - 1.9e-44 150.4 0.0 4.2e-44 149.3 0.0 1.6 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 KXS99334.1 - 1.4e-13 51.1 2.6 2.9e-13 50.1 2.6 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HSBP1 PF06825.12 KXS99334.1 - 0.074 12.9 0.1 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 Heat shock factor binding protein 1 Methyltransf_23 PF13489.6 KXS99335.1 - 1.8e-11 44.2 0.0 2.6e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS99335.1 - 6.7e-09 36.3 0.0 1.8e-08 35.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS99335.1 - 2.3e-07 31.4 0.0 6.9e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS99335.1 - 6.4e-07 30.0 0.0 2.5e-06 28.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS99335.1 - 1.3e-06 28.3 0.0 3.8e-06 26.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXS99335.1 - 0.00036 20.0 0.0 0.0007 19.0 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family CheR PF01739.18 KXS99335.1 - 0.016 14.7 0.0 0.046 13.2 0.0 1.7 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain DUF86 PF01934.17 KXS99335.1 - 0.035 14.0 0.1 0.063 13.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF86 Chitin_synth_2 PF03142.15 KXS99336.1 - 1.6e-29 102.9 0.0 3.7e-24 85.2 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.6 KXS99336.1 - 2.2e-08 34.3 0.0 5.2e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KXS99336.1 - 4.6e-05 23.3 0.0 0.018 14.9 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 KXS99336.1 - 0.00041 20.3 4.9 0.001 19.0 4.9 1.7 1 1 0 1 1 1 1 Glycosyl transferase family group 2 CBP_CCPA PF17040.5 KXS99336.1 - 0.11 13.1 2.7 0.17 12.5 0.5 2.3 1 1 1 2 2 2 0 Cellulose-complementing protein A DHHC PF01529.20 KXS99337.1 - 2.6 8.2 8.0 0.91 9.6 1.5 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase SKIP_SNW PF02731.15 KXS99338.1 - 2.1e-69 232.3 6.4 2.1e-69 232.3 6.4 2.3 2 0 0 2 2 2 1 SKIP/SNW domain SR-25 PF10500.9 KXS99338.1 - 0.088 12.4 28.3 0.16 11.5 28.3 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein 4HBT PF03061.22 KXS99339.1 - 0.00017 21.8 0.1 0.00051 20.3 0.1 1.8 1 1 0 1 1 1 1 Thioesterase superfamily SARAF PF06682.12 KXS99341.1 - 3.3e-108 362.3 5.8 3.9e-108 362.0 5.8 1.0 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis SARAF PF06682.12 KXS99342.1 - 3.3e-108 362.3 5.8 3.9e-108 362.0 5.8 1.0 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis DLH PF01738.18 KXS99343.1 - 8.8e-23 81.0 0.0 1.3e-22 80.5 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family EMP24_GP25L PF01105.24 KXS99344.1 - 4.4e-46 157.1 0.1 5e-46 156.9 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD UPRTase PF14681.6 KXS99345.1 - 1.3e-78 263.2 0.0 1.8e-78 262.7 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KXS99345.1 - 0.0011 18.5 0.0 0.0016 17.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain HET PF06985.11 KXS99346.1 - 1.7e-30 106.3 1.7 3.2e-30 105.4 1.7 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PAN_1 PF00024.26 KXS99348.1 - 0.0032 17.4 17.0 0.17 11.8 2.5 4.6 4 0 0 4 4 4 2 PAN domain PAN_3 PF08277.12 KXS99348.1 - 0.03 14.1 1.1 0.03 14.1 1.1 4.1 5 0 0 5 5 5 0 PAN-like domain zf-ribbon_3 PF13248.6 KXS99348.1 - 2.9 7.4 11.5 16 5.1 1.2 4.1 3 0 0 3 3 3 0 zinc-ribbon domain Anti-TRAP PF15777.5 KXS99348.1 - 6.3 6.8 11.1 42 4.2 0.9 3.8 3 0 0 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein Kin17_mid PF10357.9 KXS99349.1 - 2.6e-51 172.8 1.1 2.6e-51 172.8 1.1 2.1 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.8 KXS99349.1 - 1.3e-05 25.4 1.1 2.7e-05 24.3 1.1 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXS99349.1 - 3.6e-05 24.0 2.1 6.7e-05 23.1 2.1 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KXS99349.1 - 0.0014 19.0 5.8 0.0034 17.7 0.7 2.5 1 1 0 2 2 2 1 C2H2 type zinc-finger (2 copies) LIDHydrolase PF10230.9 KXS99350.1 - 3.6e-48 164.4 0.0 5.3e-48 163.9 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 KXS99350.1 - 0.00018 22.2 0.3 0.00024 21.8 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXS99350.1 - 0.0034 16.7 0.0 0.0062 15.8 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF900 PF05990.12 KXS99350.1 - 0.0059 16.1 0.0 0.011 15.3 0.0 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) LCAT PF02450.15 KXS99350.1 - 0.018 14.3 0.0 0.028 13.6 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Peptidase_M18 PF02127.15 KXS99353.1 - 5e-79 266.1 0.0 6.8e-79 265.7 0.0 1.1 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Pyr_redox_2 PF07992.14 KXS99354.1 - 5.7e-15 55.3 0.0 4.8e-09 35.9 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXS99354.1 - 0.00021 20.7 0.0 0.028 13.7 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXS99354.1 - 0.0003 20.0 0.1 0.00083 18.5 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 KXS99354.1 - 0.00055 19.1 0.1 0.026 13.6 0.1 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 KXS99354.1 - 0.00059 18.7 0.1 0.0011 17.7 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein K_oxygenase PF13434.6 KXS99354.1 - 0.0012 18.1 0.3 0.0052 16.0 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KXS99354.1 - 0.0038 17.4 0.2 0.0098 16.1 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KXS99354.1 - 0.0055 15.8 0.3 0.038 13.0 0.2 2.0 1 1 1 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 KXS99354.1 - 0.014 15.4 0.1 3.9 7.4 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KXS99354.1 - 0.046 13.0 0.0 0.072 12.3 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 KXS99354.1 - 0.086 12.2 0.6 0.13 11.5 0.6 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Cation_efflux PF01545.21 KXS99355.1 - 5.2e-26 91.6 11.8 6.7e-26 91.3 11.8 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KXS99355.1 - 2.1e-07 30.9 0.1 4.2e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter GTP_CH_N PF12471.8 KXS99356.1 - 5.8e-91 303.5 0.0 9.3e-91 302.8 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 KXS99356.1 - 1.2e-17 64.0 0.0 1.8e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II EthD PF07110.11 KXS99357.1 - 3.5e-16 60.1 0.9 5.4e-16 59.5 0.9 1.3 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 KXS99357.1 - 7.6e-06 26.4 0.7 2.9e-05 24.5 0.7 1.9 1 1 0 1 1 1 1 Methylmuconolactone methyl-isomerase Ras PF00071.22 KXS99358.1 - 2.7e-45 153.9 0.2 3.2e-45 153.6 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXS99358.1 - 1.4e-15 57.5 0.1 2.3e-15 56.9 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXS99358.1 - 1.5e-08 34.3 0.0 1.7e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KXS99358.1 - 1.3e-05 24.7 0.1 1.7e-05 24.3 0.1 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KXS99358.1 - 5.1e-05 23.2 0.0 0.011 15.6 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KXS99358.1 - 5.6e-05 23.2 0.1 0.0001 22.4 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KXS99358.1 - 0.00031 20.3 1.7 0.0028 17.2 0.9 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KXS99358.1 - 0.00032 20.2 0.1 0.0059 16.1 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_14 PF13173.6 KXS99358.1 - 0.072 13.1 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain BRE1 PF08647.11 KXS99359.1 - 6.7e-30 103.0 10.2 6.7e-30 103.0 10.2 7.0 5 1 2 7 7 7 1 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.6 KXS99359.1 - 3.8e-09 36.2 6.5 7.5e-09 35.3 6.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXS99359.1 - 4.5e-09 36.0 7.3 8.2e-09 35.2 7.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS99359.1 - 4e-08 33.0 9.2 7.5e-08 32.1 9.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXS99359.1 - 4.5e-07 30.1 7.7 7.7e-07 29.3 7.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KXS99359.1 - 2.8e-06 27.2 8.5 5.1e-06 26.3 8.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXS99359.1 - 6.2e-06 26.1 8.6 1.3e-05 25.2 8.6 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KXS99359.1 - 3.7e-05 23.8 7.5 6.9e-05 22.9 7.5 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KXS99359.1 - 4.5e-05 23.2 7.7 8.6e-05 22.3 7.7 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KXS99359.1 - 0.0013 19.0 3.8 0.0045 17.3 3.8 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain TerY_C PF15616.6 KXS99359.1 - 0.0028 17.8 2.5 0.0085 16.2 2.5 1.8 1 0 0 1 1 1 1 TerY-C metal binding domain zinc-ribbons_6 PF07191.12 KXS99359.1 - 0.0079 16.2 5.3 0.0081 16.1 3.3 2.0 1 1 0 1 1 1 1 zinc-ribbons DUF4407 PF14362.6 KXS99359.1 - 0.0091 15.4 1.7 0.0091 15.4 1.7 5.1 1 1 4 5 5 5 1 Domain of unknown function (DUF4407) zf-Nse PF11789.8 KXS99359.1 - 0.062 13.1 3.3 0.16 11.8 3.3 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 KXS99359.1 - 0.067 13.0 6.0 0.24 11.2 6.2 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain NADH-G_4Fe-4S_3 PF10588.9 KXS99359.1 - 0.083 12.4 1.7 0.31 10.6 0.1 2.4 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region zf-Di19 PF05605.12 KXS99359.1 - 0.51 10.7 5.3 4.9 7.5 5.4 2.5 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DUF4250 PF14056.6 KXS99359.1 - 0.61 10.1 5.0 0.75 9.8 0.2 3.6 3 0 0 3 3 2 0 Domain of unknown function (DUF4250) Zn_ribbon_17 PF17120.5 KXS99359.1 - 0.7 9.6 4.9 1.4 8.6 4.9 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_6 PF14835.6 KXS99359.1 - 0.82 9.6 4.8 1.8 8.5 4.8 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein FYVE PF01363.21 KXS99359.1 - 1.3 9.2 7.4 9.8 6.4 7.3 2.4 1 1 1 2 2 2 0 FYVE zinc finger zf-C2H2_4 PF13894.6 KXS99359.1 - 8 7.6 6.9 8.5 7.5 0.4 3.2 3 0 0 3 3 2 0 C2H2-type zinc finger USP7_ICP0_bdg PF12436.8 KXS99360.1 - 3.7e-81 272.0 0.5 1.4e-80 270.1 0.0 2.0 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 KXS99360.1 - 6.8e-66 221.9 2.9 1.7e-65 220.6 2.9 1.7 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal UCH PF00443.29 KXS99360.1 - 1.4e-46 159.1 1.2 2e-46 158.6 0.6 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXS99360.1 - 6.4e-17 62.1 0.0 6e-16 58.9 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 KXS99360.1 - 4.3e-05 23.6 0.0 0.00015 21.9 0.0 1.9 1 0 0 1 1 1 1 MATH domain zf-C2H2 PF00096.26 KXS99361.1 - 4.2e-17 61.6 22.4 0.00037 20.8 0.3 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXS99361.1 - 3.3e-14 52.6 25.9 4e-08 33.3 1.3 5.1 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXS99361.1 - 2.7e-08 34.0 20.2 0.043 14.7 0.8 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KXS99361.1 - 4e-05 23.8 6.9 0.024 14.9 1.5 3.5 1 1 2 3 3 3 3 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 KXS99361.1 - 0.0063 16.7 5.7 0.43 10.7 0.3 3.3 2 1 1 3 3 3 1 Aberrant zinc-finger zf-met PF12874.7 KXS99361.1 - 0.0078 16.6 11.1 0.24 11.9 0.3 4.1 4 0 0 4 4 4 2 Zinc-finger of C2H2 type RteC PF09357.10 KXS99361.1 - 0.02 14.6 0.1 0.042 13.5 0.1 1.5 1 0 0 1 1 1 0 RteC protein FOXP-CC PF16159.5 KXS99361.1 - 0.12 13.0 3.9 21 5.8 0.1 3.7 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-DNA_Pol PF08996.10 KXS99361.1 - 0.59 9.9 5.2 2.8 7.6 1.2 2.3 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger zf-LYAR PF08790.11 KXS99361.1 - 1.2 9.1 11.6 25 4.9 0.1 4.3 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger FYVE PF01363.21 KXS99361.1 - 2.3 8.4 6.5 1 9.5 3.2 2.0 2 1 1 3 3 3 0 FYVE zinc finger zf-C2H2_4 PF13894.6 KXS99364.1 - 0.00025 21.6 0.4 0.00055 20.6 0.4 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.26 KXS99364.1 - 0.00059 20.1 0.9 0.0014 19.0 0.9 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 KXS99364.1 - 0.044 13.6 0.6 0.11 12.3 0.6 1.6 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 KXS99364.1 - 0.052 14.2 0.0 0.17 12.6 0.0 2.0 1 0 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats ROKNT PF08067.11 KXS99364.1 - 4.9 7.5 6.6 1.4 9.3 0.4 3.2 3 0 0 3 3 3 0 ROKNT (NUC014) domain Zn_clus PF00172.18 KXS99365.1 - 2.1e-06 27.7 9.5 3.5e-06 27.0 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3738 PF12543.8 KXS99365.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3738) P21-Arc PF04062.14 KXS99366.1 - 1.4e-74 249.9 0.0 1.6e-74 249.7 0.0 1.1 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Pep3_Vps18 PF05131.14 KXS99369.1 - 5.8e-45 152.7 0.0 1.3e-44 151.6 0.0 1.7 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 KXS99369.1 - 4.7e-13 49.2 4.7 2.4e-10 40.4 0.5 3.5 3 0 0 3 3 3 2 Region in Clathrin and VPS zf-RING_5 PF14634.6 KXS99369.1 - 0.002 18.1 0.2 0.0044 17.0 0.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 KXS99369.1 - 0.006 16.2 0.3 0.012 15.2 0.3 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 KXS99369.1 - 0.0064 16.2 2.2 0.02 14.6 2.2 1.8 1 0 0 1 1 1 1 RING-like zinc finger Nup54_57_C PF18570.1 KXS99369.1 - 0.014 15.0 0.3 0.066 12.8 0.1 2.3 2 0 0 2 2 2 0 NUP57/Nup54 C-terminal domain Vps39_2 PF10367.9 KXS99369.1 - 0.02 15.3 0.0 0.058 13.8 0.0 1.8 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-rbx1 PF12678.7 KXS99369.1 - 0.11 12.7 0.5 0.3 11.4 0.5 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KXS99369.1 - 0.14 12.1 1.8 0.33 10.8 1.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXS99369.1 - 0.15 12.1 0.1 0.32 11.1 0.1 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3H2C3 PF17122.5 KXS99369.1 - 0.15 12.1 0.6 0.29 11.2 0.6 1.4 1 0 0 1 1 1 0 Zinc-finger DUF1664 PF07889.12 KXS99369.1 - 0.17 11.9 1.7 0.34 10.9 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ANAPC3 PF12895.7 KXS99369.1 - 0.19 12.0 1.5 7.8 6.8 0.1 3.5 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 zf-RING_2 PF13639.6 KXS99369.1 - 0.31 11.4 1.4 1 9.7 1.4 1.9 1 0 0 1 1 1 0 Ring finger domain Pep3_Vps18 PF05131.14 KXS99370.1 - 5.8e-45 152.7 0.0 1.3e-44 151.6 0.0 1.7 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 KXS99370.1 - 4.7e-13 49.2 4.7 2.4e-10 40.4 0.5 3.5 3 0 0 3 3 3 2 Region in Clathrin and VPS zf-RING_5 PF14634.6 KXS99370.1 - 0.002 18.1 0.2 0.0044 17.0 0.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 KXS99370.1 - 0.006 16.2 0.3 0.012 15.2 0.3 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 KXS99370.1 - 0.0064 16.2 2.2 0.02 14.6 2.2 1.8 1 0 0 1 1 1 1 RING-like zinc finger Nup54_57_C PF18570.1 KXS99370.1 - 0.014 15.0 0.3 0.066 12.8 0.1 2.3 2 0 0 2 2 2 0 NUP57/Nup54 C-terminal domain Vps39_2 PF10367.9 KXS99370.1 - 0.02 15.3 0.0 0.058 13.8 0.0 1.8 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-rbx1 PF12678.7 KXS99370.1 - 0.11 12.7 0.5 0.3 11.4 0.5 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KXS99370.1 - 0.14 12.1 1.8 0.33 10.8 1.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXS99370.1 - 0.15 12.1 0.1 0.32 11.1 0.1 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3H2C3 PF17122.5 KXS99370.1 - 0.15 12.1 0.6 0.29 11.2 0.6 1.4 1 0 0 1 1 1 0 Zinc-finger DUF1664 PF07889.12 KXS99370.1 - 0.17 11.9 1.7 0.34 10.9 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ANAPC3 PF12895.7 KXS99370.1 - 0.19 12.0 1.5 7.8 6.8 0.1 3.5 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 zf-RING_2 PF13639.6 KXS99370.1 - 0.31 11.4 1.4 1 9.7 1.4 1.9 1 0 0 1 1 1 0 Ring finger domain Pmp3 PF01679.17 KXS99374.1 - 1e-18 67.2 2.2 1.6e-18 66.6 2.2 1.3 1 0 0 1 1 1 1 Proteolipid membrane potential modulator GRDP-like PF07173.12 KXS99375.1 - 3.9e-18 66.5 2.8 8.1e-15 55.7 0.1 2.8 3 0 0 3 3 3 2 Glycine-rich domain-containing protein-like Perm-CXXC PF15629.6 KXS99375.1 - 2.8 8.3 8.6 6.9 7.0 2.8 2.5 2 0 0 2 2 2 0 Permuted single zf-CXXC unit Myb_DNA-bind_7 PF15963.5 KXS99376.1 - 3.5e-24 84.5 0.2 3.5e-24 84.5 0.2 2.5 1 1 1 2 2 2 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 KXS99376.1 - 3.3e-07 30.4 0.0 8.2e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain HIGH_NTase1_ass PF16581.5 KXS99376.1 - 0.017 15.1 0.6 0.034 14.1 0.6 1.4 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region AAA_23 PF13476.6 KXS99376.1 - 0.77 10.2 10.7 4.8 7.6 0.8 2.2 2 0 0 2 2 2 0 AAA domain WD40 PF00400.32 KXS99377.1 - 7.2e-63 207.0 13.2 1.2e-09 38.7 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS99377.1 - 8e-21 74.2 0.0 0.00017 21.8 0.0 6.3 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Tup_N PF08581.10 KXS99377.1 - 1.9e-17 63.4 12.3 3.4e-17 62.5 12.3 1.5 1 0 0 1 1 1 1 Tup N-terminal WD40_like PF17005.5 KXS99377.1 - 2.3e-07 30.5 0.0 0.031 13.6 0.0 4.2 4 1 1 5 5 5 2 WD40-like domain Cytochrom_D1 PF02239.16 KXS99377.1 - 2.9e-07 29.3 0.1 3.7e-05 22.4 0.1 2.6 1 1 1 2 2 2 2 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 KXS99377.1 - 8e-07 28.3 0.2 0.35 9.8 0.0 5.7 1 1 5 7 7 7 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KXS99377.1 - 2e-05 24.6 0.0 0.052 13.4 0.0 3.3 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KXS99377.1 - 3e-05 22.9 0.4 0.21 10.2 0.0 3.2 1 1 3 4 4 4 2 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.14 KXS99377.1 - 0.034 13.2 0.0 0.088 11.8 0.0 1.5 1 1 0 1 1 1 0 Coatomer WD associated region PD40 PF07676.12 KXS99377.1 - 0.037 14.0 0.0 7.3 6.7 0.0 4.3 6 0 0 6 6 5 0 WD40-like Beta Propeller Repeat MMS1_N PF10433.9 KXS99377.1 - 0.037 12.7 0.0 5.9 5.4 0.0 2.2 2 0 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term VID27 PF08553.10 KXS99377.1 - 0.065 12.3 0.0 2.5 7.1 0.0 2.5 1 1 2 3 3 3 0 VID27 C-terminal WD40-like domain Golgin_A5 PF09787.9 KXS99377.1 - 0.13 11.7 5.6 0.18 11.2 5.6 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Nbas_N PF15492.6 KXS99377.1 - 0.14 11.4 0.0 24 4.2 0.0 2.8 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Inh PF02974.14 KXS99377.1 - 0.19 11.8 0.2 29 4.8 0.0 3.7 3 1 1 4 4 4 0 Protease inhibitor Inh DUF3037 PF11236.8 KXS99377.1 - 0.28 11.6 1.5 0.51 10.8 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) DUF3523 PF12037.8 KXS99377.1 - 0.59 9.5 6.4 0.84 9.0 6.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) ORC6 PF05460.13 KXS99378.1 - 1.6e-30 106.6 11.5 1.4e-28 100.2 11.5 2.3 1 1 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) ABC_membrane PF00664.23 KXS99379.1 - 1.1e-109 366.3 37.6 1.1e-56 192.5 11.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXS99379.1 - 5.5e-68 227.7 0.0 8.1e-33 113.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KXS99379.1 - 1.7e-15 57.0 0.0 1.8e-05 24.3 0.0 3.5 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KXS99379.1 - 2.6e-07 30.3 0.3 0.0037 17.0 0.3 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KXS99379.1 - 7.2e-07 29.3 0.0 0.15 11.9 0.0 3.4 3 0 0 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 KXS99379.1 - 9.2e-06 26.1 4.8 0.062 13.7 0.2 3.4 2 2 1 3 3 2 2 AAA ATPase domain ABC_ATPase PF09818.9 KXS99379.1 - 9.7e-06 24.6 4.3 0.016 14.0 0.0 2.9 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA PF00004.29 KXS99379.1 - 0.0002 21.8 2.4 7.2 7.0 0.0 4.7 3 1 1 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KXS99379.1 - 0.00022 20.9 0.0 0.27 10.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KXS99379.1 - 0.00025 20.9 0.0 0.81 9.3 0.0 2.9 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 KXS99379.1 - 0.00044 20.5 2.5 0.28 11.4 0.1 3.5 2 2 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KXS99379.1 - 0.00088 19.0 3.6 0.82 9.4 0.6 3.9 3 1 0 3 3 3 2 AAA domain DUF815 PF05673.13 KXS99379.1 - 0.0016 17.6 0.0 1.6 7.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) G-alpha PF00503.20 KXS99379.1 - 0.0018 17.5 0.0 0.89 8.6 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_28 PF13521.6 KXS99379.1 - 0.0019 18.4 0.2 0.32 11.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 KXS99379.1 - 0.0045 17.2 3.3 2.3 8.5 0.4 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 KXS99379.1 - 0.0079 16.0 1.1 6.8 6.4 0.1 3.6 3 1 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 KXS99379.1 - 0.0097 16.0 0.2 3.5 7.6 0.2 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_7 PF12775.7 KXS99379.1 - 0.014 14.9 0.0 5 6.6 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_33 PF13671.6 KXS99379.1 - 0.021 15.0 0.0 9.4 6.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KXS99379.1 - 0.042 13.8 2.1 13 5.8 0.0 3.5 4 0 0 4 4 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KXS99379.1 - 0.052 13.3 0.1 3.7 7.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 KXS99379.1 - 0.055 13.2 0.0 1.5 8.5 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_23 PF13476.6 KXS99379.1 - 0.059 13.9 1.9 5.2 7.5 0.0 3.2 3 0 0 3 3 3 0 AAA domain SRP54 PF00448.22 KXS99379.1 - 0.063 12.9 0.8 2.7 7.6 0.0 2.7 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain Rad17 PF03215.15 KXS99379.1 - 0.067 13.1 0.0 0.35 10.8 0.0 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain APS_kinase PF01583.20 KXS99379.1 - 0.069 13.0 0.2 1.6 8.6 0.1 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_18 PF13238.6 KXS99379.1 - 0.087 13.4 1.6 20 5.7 0.0 3.2 3 0 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KXS99379.1 - 0.091 12.1 0.1 7.9 5.7 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zeta_toxin PF06414.12 KXS99379.1 - 0.091 12.0 3.7 4.7 6.4 0.0 3.1 4 0 0 4 4 3 0 Zeta toxin ATP-synt_ab PF00006.25 KXS99379.1 - 0.094 12.3 0.0 20 4.8 0.0 2.7 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.22 KXS99379.1 - 0.23 11.9 1.0 12 6.4 0.0 3.3 4 0 0 4 4 2 0 RNA helicase MMR_HSR1 PF01926.23 KXS99379.1 - 0.46 10.6 2.0 11 6.2 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase Elf1 PF05129.13 KXS99380.1 - 6.8e-30 102.9 2.4 8.5e-30 102.6 2.4 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Vps36-NZF-N PF16988.5 KXS99380.1 - 0.02 14.3 0.4 0.039 13.3 0.4 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-Sec23_Sec24 PF04810.15 KXS99380.1 - 0.12 12.4 0.8 0.12 12.4 0.8 2.1 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger Ribosomal_L37ae PF01780.19 KXS99380.1 - 0.13 12.4 5.6 0.08 13.0 0.8 2.1 1 1 1 2 2 2 0 Ribosomal L37ae protein family Zn-ribbon_8 PF09723.10 KXS99380.1 - 0.18 11.9 0.9 0.4 10.8 0.9 1.6 1 1 0 1 1 1 0 Zinc ribbon domain Erf4 PF10256.9 KXS99381.1 - 3.4e-37 127.1 0.0 4.4e-37 126.7 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Ribosomal_L31 PF01197.18 KXS99397.1 - 1.7e-05 25.0 0.1 3e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L31 DUF2385 PF09539.10 KXS99397.1 - 0.14 12.7 0.7 0.31 11.6 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) Mito_carr PF00153.27 KXS99398.1 - 1.7e-67 223.4 2.6 1.7e-22 79.1 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein eIF2A PF08662.11 KXS99401.1 - 3.8e-83 278.1 0.0 1.1e-81 273.4 0.1 2.2 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 KXS99401.1 - 0.0064 17.3 1.5 1.6 9.7 0.1 4.5 3 2 0 4 4 4 1 WD domain, G-beta repeat PD40 PF07676.12 KXS99401.1 - 0.44 10.6 11.1 2.3 8.2 0.1 5.2 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat FAM220 PF15487.6 KXS99401.1 - 0.46 10.1 5.3 0.72 9.4 5.3 1.2 1 0 0 1 1 1 0 FAM220 family Proteasome_A_N PF10584.9 KXS99401.1 - 0.62 9.8 5.5 3.2 7.5 0.0 3.9 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Mon1 PF03164.14 KXS99402.1 - 3.2e-155 517.2 0.0 3.7e-155 517.0 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 Inhibitor_Mig-6 PF11555.8 KXS99402.1 - 3.2 7.9 8.7 7.2 6.8 8.7 1.6 1 0 0 1 1 1 0 EGFR receptor inhibitor Mig-6 Ribosomal_S10 PF00338.22 KXS99403.1 - 6e-26 90.5 0.2 7.7e-26 90.2 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e ARID PF01388.21 KXS99404.1 - 1.8e-18 67.0 0.4 1.5e-17 64.0 0.0 2.8 3 0 0 3 3 3 1 ARID/BRIGHT DNA binding domain DUF2353 PF09789.9 KXS99404.1 - 6.3 6.1 8.6 11 5.3 8.6 1.3 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Ferric_reduct PF01794.19 KXS99405.1 - 3.2e-20 72.5 13.7 3.2e-20 72.5 13.7 3.0 2 2 2 4 4 4 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KXS99405.1 - 2.3e-13 50.2 0.0 5.1e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain DUF4405 PF14358.6 KXS99405.1 - 0.065 13.8 1.1 0.065 13.8 1.1 4.1 4 1 0 4 4 4 0 Domain of unknown function (DUF4405) Serglycin PF04360.12 KXS99406.1 - 0.12 12.3 1.6 0.22 11.5 1.6 1.3 1 0 0 1 1 1 0 Serglycin Serglycin PF04360.12 KXS99407.1 - 0.12 12.3 1.6 0.22 11.5 1.6 1.3 1 0 0 1 1 1 0 Serglycin Ferric_reduct PF01794.19 KXS99408.1 - 3.1e-20 72.5 13.7 3.1e-20 72.5 13.7 3.0 2 2 1 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KXS99408.1 - 2.2e-13 50.2 0.0 4.9e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain DUF4405 PF14358.6 KXS99408.1 - 0.064 13.8 1.1 0.064 13.8 1.1 4.0 4 1 0 4 4 4 0 Domain of unknown function (DUF4405) BLACT_WH PF17778.1 KXS99413.1 - 4.2e-17 61.9 0.0 9.4e-17 60.7 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B PF00753.27 KXS99413.1 - 9e-16 58.5 0.3 1.9e-15 57.4 0.3 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RRM_1 PF00076.22 KXS99413.1 - 3e-06 27.0 0.2 7.2e-06 25.7 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lactamase_B_2 PF12706.7 KXS99413.1 - 0.00059 19.4 0.0 0.0014 18.1 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RRM_5 PF13893.6 KXS99413.1 - 0.0032 17.1 0.0 0.0071 15.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 KXS99413.1 - 0.094 12.9 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 RRM-like domain D-ser_dehydrat PF14031.6 KXS99414.1 - 2.8e-22 79.2 0.0 6.1e-22 78.1 0.0 1.6 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 KXS99414.1 - 1.6e-11 44.3 0.0 2.4e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Aminotran_5 PF00266.19 KXS99415.1 - 5.1e-21 75.0 0.0 2.5e-18 66.2 0.0 2.9 1 1 0 1 1 1 1 Aminotransferase class-V TLD PF07534.16 KXS99416.1 - 9.7e-26 90.7 0.0 3.2e-14 53.3 0.0 2.2 2 0 0 2 2 2 2 TLD COX6B PF02297.17 KXS99417.1 - 8.2e-23 80.4 2.6 1e-22 80.1 2.6 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb DegS PF05384.11 KXS99418.1 - 0.028 13.9 2.3 0.051 13.1 1.9 1.8 1 1 0 1 1 1 0 Sensor protein DegS LPD15 PF18828.1 KXS99418.1 - 0.041 13.7 0.3 0.1 12.5 0.3 1.6 1 0 0 1 1 1 0 Large polyvalent-protein-associated domain 15 Defensin_like PF10868.8 KXS99419.1 - 0.013 16.2 15.4 0.024 15.4 15.4 1.5 1 1 0 1 1 1 0 Cysteine-rich antifungal protein 2, defensin-like Bromodomain PF00439.25 KXS99420.1 - 4.8e-17 61.8 0.3 9.3e-17 60.9 0.3 1.5 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.13 KXS99420.1 - 5.5e-08 32.7 0.0 1.7e-07 31.1 0.0 1.8 2 0 0 2 2 2 1 Bromodomain associated PBP1_TM PF14812.6 KXS99420.1 - 7.9 6.9 29.6 0.031 14.6 7.1 4.2 4 0 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Zn_clus PF00172.18 KXS99421.1 - 4.9e-06 26.6 6.2 1e-05 25.5 6.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_19 PF14559.6 KXS99421.1 - 3.5e-05 24.2 6.3 1.1 9.8 0.3 5.4 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXS99421.1 - 0.00018 21.2 17.4 2.5 8.1 0.1 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 KXS99421.1 - 0.00069 20.2 3.7 0.87 10.3 0.1 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXS99421.1 - 0.0032 17.5 10.7 33 5.0 0.1 7.4 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_7 PF13176.6 KXS99421.1 - 0.23 11.6 7.5 44 4.4 0.0 5.9 5 1 0 5 5 5 0 Tetratricopeptide repeat HUN PF08729.10 KXS99422.1 - 6.3e-08 32.5 0.4 1.3e-07 31.5 0.4 1.5 1 0 0 1 1 1 1 HPC2 and ubinuclein domain CP2 PF04516.15 KXS99423.1 - 3.3e-84 281.8 0.0 5.8e-84 281.0 0.0 1.3 1 0 0 1 1 1 1 CP2 transcription factor Tektin PF03148.14 KXS99423.1 - 0.1 11.4 0.1 0.16 10.7 0.1 1.2 1 0 0 1 1 1 0 Tektin family Rabaptin PF03528.15 KXS99426.1 - 0.046 12.4 1.7 0.07 11.8 1.7 1.2 1 0 0 1 1 1 0 Rabaptin ADH_N PF08240.12 KXS99427.1 - 4.4e-25 87.7 1.1 9.5e-25 86.6 1.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXS99427.1 - 2.6e-10 40.4 0.3 4.3e-10 39.7 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXS99427.1 - 0.00078 20.5 0.0 0.0013 19.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXS99427.1 - 0.0054 16.2 0.4 0.0084 15.6 0.4 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Megourin PF17560.2 KXS99427.1 - 0.063 13.5 1.7 15 6.0 0.6 3.1 2 1 0 2 2 2 0 Aphid Megourins 2-Hacid_dh_C PF02826.19 KXS99427.1 - 0.067 12.5 0.2 0.11 11.8 0.2 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Importin_rep_4 PF18808.1 KXS99428.1 - 9.5e-33 112.4 3.1 9.7e-32 109.1 2.7 3.0 2 0 0 2 2 2 1 Importin repeat Importin_rep_5 PF18816.1 KXS99428.1 - 1.8e-21 76.2 1.6 6e-21 74.5 1.6 2.0 1 0 0 1 1 1 1 Importin repeat HEAT_EZ PF13513.6 KXS99428.1 - 5.7e-21 74.6 15.2 3.8e-11 43.3 0.2 9.8 8 3 3 11 11 10 3 HEAT-like repeat HEAT PF02985.22 KXS99428.1 - 2.7e-18 64.5 15.8 0.00028 20.9 0.0 12.6 13 0 0 13 13 13 2 HEAT repeat HEAT_2 PF13646.6 KXS99428.1 - 2.3e-17 63.2 12.7 1.5e-08 34.9 0.1 8.2 6 2 3 9 9 7 4 HEAT repeats Importin_rep_6 PF18829.1 KXS99428.1 - 4e-13 49.4 3.4 9.7e-13 48.2 0.3 3.2 3 0 0 3 3 3 1 Importin repeat 6 CLASP_N PF12348.8 KXS99428.1 - 1.8e-09 37.5 2.7 0.012 15.2 0.0 5.9 3 2 2 5 5 5 4 CLASP N terminal Vac14_Fab1_bd PF12755.7 KXS99428.1 - 7.5e-09 36.1 0.3 0.021 15.4 0.0 6.2 5 2 1 7 7 5 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KXS99428.1 - 1.7e-07 31.5 1.3 0.013 15.5 0.0 5.1 4 1 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.12 KXS99428.1 - 3.4e-07 30.2 0.0 0.0031 17.3 0.1 4.3 3 1 0 3 3 3 1 rRNA processing/ribosome biogenesis DUF3385 PF11865.8 KXS99428.1 - 8.2e-06 25.8 0.4 0.11 12.4 0.0 5.5 2 1 2 4 4 4 2 Domain of unknown function (DUF3385) MMS19_C PF12460.8 KXS99428.1 - 9.8e-06 24.9 5.6 2.3e-05 23.7 0.0 3.8 4 0 0 4 4 4 1 RNAPII transcription regulator C-terminal Arm PF00514.23 KXS99428.1 - 0.00024 21.1 13.3 0.049 13.7 0.1 6.2 7 0 0 7 7 6 1 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 KXS99428.1 - 0.00027 19.6 0.2 0.061 11.9 0.0 3.9 2 1 2 4 4 4 2 Adaptin N terminal region MMS19_N PF14500.6 KXS99428.1 - 0.00032 20.4 0.3 1.2 8.6 0.0 4.0 4 0 0 4 4 3 2 Dos2-interacting transcription regulator of RNA-Pol-II DRIM PF07539.12 KXS99428.1 - 0.0018 16.7 1.6 0.16 10.3 0.1 3.9 2 2 1 4 4 4 1 Down-regulated in metastasis TFCD_C PF12612.8 KXS99428.1 - 0.0029 17.5 0.5 0.1 12.4 0.0 3.7 4 1 0 4 4 4 1 Tubulin folding cofactor D C terminal V-ATPase_H_N PF03224.14 KXS99428.1 - 0.011 15.1 4.1 2.2 7.5 0.0 3.9 3 1 0 3 3 3 0 V-ATPase subunit H DUF1981 PF09324.10 KXS99428.1 - 0.031 14.1 0.1 3 7.8 0.0 3.2 3 0 0 3 3 2 0 Domain of unknown function (DUF1981) YihI PF04220.12 KXS99428.1 - 0.049 13.4 0.6 0.22 11.3 0.6 2.1 1 0 0 1 1 1 0 Der GTPase activator (YihI) DUF4042 PF13251.6 KXS99428.1 - 0.081 12.6 0.1 5.2 6.7 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4042) DNA_alkylation PF08713.11 KXS99428.1 - 0.091 12.5 1.2 0.22 11.2 0.0 2.3 3 0 0 3 3 3 0 DNA alkylation repair enzyme Nse4_C PF08743.10 KXS99430.1 - 1.6 9.0 3.5 24 5.3 0.5 2.3 1 1 1 2 2 2 0 Nse4 C-terminal Peptidase_C12 PF01088.21 KXS99431.1 - 2.9e-50 171.0 0.0 3.6e-49 167.4 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Ndc1_Nup PF09531.10 KXS99431.1 - 0.12 11.1 0.1 8.9 4.9 0.4 2.0 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup MSA-2c PF12238.8 KXS99431.1 - 6.1 6.8 7.9 0.48 10.4 1.1 2.1 1 1 1 2 2 2 0 Merozoite surface antigen 2c I-set PF07679.16 KXS99434.1 - 0.024 14.7 0.2 13 6.0 0.0 4.4 4 0 0 4 4 4 0 Immunoglobulin I-set domain F-box PF00646.33 KXS99435.1 - 0.0004 20.2 0.4 0.0011 18.8 0.0 1.9 2 0 0 2 2 2 1 F-box domain CotJA PF11007.8 KXS99436.1 - 0.018 14.8 0.0 0.033 14.0 0.0 1.4 1 0 0 1 1 1 0 Spore coat associated protein JA (CotJA) THUMP PF02926.17 KXS99437.1 - 2.7e-11 43.7 0.1 5.3e-11 42.8 0.1 1.6 1 0 0 1 1 1 1 THUMP domain Fungal_trans_2 PF11951.8 KXS99438.1 - 0.00012 21.0 0.1 0.013 14.3 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Ribosomal_S2 PF00318.20 KXS99440.1 - 5.3e-63 212.1 0.0 1.6e-62 210.5 0.0 1.7 1 1 0 1 1 1 1 Ribosomal protein S2 Img2 PF05046.14 KXS99441.1 - 9.6e-24 83.5 0.0 1.3e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) Dopey_N PF04118.14 KXS99442.1 - 1.9e-107 358.9 0.0 1.3e-106 356.2 0.0 2.3 2 0 0 2 2 2 1 Dopey, N-terminal Peptidase_M50 PF02163.22 KXS99442.1 - 0.035 13.4 0.0 0.062 12.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M50 WD40 PF00400.32 KXS99443.1 - 4.2e-43 144.5 18.2 5.5e-08 33.4 0.1 7.0 6 1 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 KXS99443.1 - 1.8e-39 134.9 0.0 2.6e-39 134.4 0.0 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 KXS99443.1 - 1e-09 38.6 0.1 0.027 14.8 0.0 5.1 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 KXS99443.1 - 9.3e-07 28.6 0.0 2.1e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 LisH Nup160 PF11715.8 KXS99443.1 - 0.066 11.9 1.7 19 3.8 0.0 3.6 3 1 1 4 4 4 0 Nucleoporin Nup120/160 RAB3GAP2_N PF14655.6 KXS99443.1 - 0.11 11.8 0.0 2.9 7.1 0.0 2.7 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PALB2_WD40 PF16756.5 KXS99443.1 - 0.22 10.4 0.6 0.37 9.6 0.6 1.4 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain RPAP1_C PF08620.10 KXS99444.1 - 2.7e-27 94.7 0.0 4.9e-27 93.8 0.0 1.5 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 KXS99444.1 - 4.5e-15 55.1 1.2 4.5e-15 55.1 1.2 1.8 2 0 0 2 2 2 1 RPAP1-like, N-terminal TFIIA PF03153.13 KXS99444.1 - 0.052 13.5 14.3 0.076 13.0 14.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Na_trans_assoc PF06512.13 KXS99444.1 - 0.26 11.6 12.5 0.4 10.9 12.5 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated BUD22 PF09073.10 KXS99444.1 - 0.84 8.9 21.9 1.1 8.5 21.9 1.2 1 0 0 1 1 1 0 BUD22 Sporozoite_P67 PF05642.11 KXS99444.1 - 4.9 5.1 10.1 7.4 4.5 10.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nucleo_P87 PF07267.11 KXS99444.1 - 7.9 5.2 9.6 11 4.8 9.6 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 VanZ PF04892.12 KXS99445.1 - 9.1e-05 23.1 0.2 0.00012 22.7 0.2 1.2 1 0 0 1 1 1 1 VanZ like family Phage_holin_2_4 PF16082.5 KXS99445.1 - 0.12 12.2 0.0 0.54 10.0 0.0 2.1 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like MFS_1 PF07690.16 KXS99446.1 - 1.5e-18 66.9 68.1 1.2e-15 57.3 42.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Med11 PF10280.9 KXS99450.1 - 7.9e-39 133.3 0.7 1.1e-38 132.8 0.7 1.2 1 0 0 1 1 1 1 Mediator complex protein DD_K PF12121.8 KXS99450.1 - 0.091 12.9 0.2 0.18 12.0 0.2 1.5 1 0 0 1 1 1 0 Dermaseptin eIF3_N PF09440.10 KXS99451.1 - 3.6e-46 156.9 2.1 8.8e-46 155.6 2.1 1.7 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 KXS99451.1 - 1.8e-13 50.9 0.1 7.4e-13 48.9 0.0 2.0 2 0 0 2 2 2 1 PCI domain CUE PF02845.16 KXS99452.1 - 2.5e-09 36.6 1.1 5.3e-09 35.6 0.5 1.9 2 0 0 2 2 2 1 CUE domain tRNA_bind_3 PF17176.4 KXS99452.1 - 0.0025 18.1 0.1 0.0062 16.8 0.1 1.6 1 0 0 1 1 1 1 tRNA-binding domain FXMRP1_C_core PF12235.8 KXS99452.1 - 4 8.1 13.8 1.5 9.5 9.5 2.2 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal RF-1 PF00472.20 KXS99453.1 - 6.1e-20 71.3 1.2 9e-20 70.8 1.2 1.2 1 0 0 1 1 1 1 RF-1 domain DUF2828 PF11443.8 KXS99453.1 - 0.03 12.4 0.0 0.04 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Flavin_Reduct PF01613.18 KXS99454.1 - 1.9e-16 60.5 0.8 2.2e-15 57.0 0.0 2.9 2 1 1 3 3 3 1 Flavin reductase like domain CDC45 PF02724.14 KXS99458.1 - 0.17 10.1 17.2 0.18 10.0 17.2 1.0 1 0 0 1 1 1 0 CDC45-like protein CNDH2_C PF16858.5 KXS99458.1 - 0.47 10.3 11.9 0.5 10.2 11.9 1.0 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Nop14 PF04147.12 KXS99458.1 - 0.52 8.4 23.3 0.65 8.1 23.3 1.1 1 0 0 1 1 1 0 Nop14-like family SURF2 PF05477.11 KXS99458.1 - 1.3 8.6 13.1 1.5 8.4 13.1 1.0 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) SDA1 PF05285.12 KXS99458.1 - 2.5 7.4 22.8 3.1 7.1 22.8 1.0 1 0 0 1 1 1 0 SDA1 Hid1 PF12722.7 KXS99458.1 - 4.1 5.4 5.2 4.4 5.3 5.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein YqfQ PF14181.6 KXS99458.1 - 5.7 7.1 6.9 6.8 6.9 6.9 1.1 1 0 0 1 1 1 0 YqfQ-like protein DNA_pol_phi PF04931.13 KXS99458.1 - 5.9 4.9 27.4 6.2 4.8 27.4 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF3176 PF11374.8 KXS99459.1 - 6.3e-33 113.2 0.0 8.2e-33 112.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Acyl_transf_3 PF01757.22 KXS99460.1 - 1.1e-30 106.9 17.9 1.6e-30 106.3 17.9 1.2 1 0 0 1 1 1 1 Acyltransferase family Voltage_CLC PF00654.20 KXS99461.1 - 7.2e-90 301.8 26.1 1.1e-89 301.2 26.1 1.3 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 KXS99461.1 - 8.7e-10 38.9 0.0 4.1e-06 27.1 0.0 2.7 2 0 0 2 2 2 2 CBS domain BTB PF00651.31 KXS99462.1 - 0.00032 20.9 0.0 0.0042 17.3 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain Homeobox_KN PF05920.11 KXS99464.1 - 2.4e-16 59.4 0.3 6.5e-16 58.0 0.3 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KXS99464.1 - 2.1e-10 40.3 0.5 5.6e-10 38.9 0.5 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KXS99465.1 - 1.9e-14 53.3 0.1 5.8e-14 51.7 0.1 1.9 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KXS99465.1 - 3.2e-08 33.3 0.2 7.7e-07 28.9 0.2 2.6 1 1 0 1 1 1 1 Homeodomain Aldo_ket_red PF00248.21 KXS99466.1 - 2.8e-63 213.9 0.0 3.1e-63 213.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Peptidase_M41 PF01434.18 KXS99467.1 - 1.8e-58 197.6 1.2 3.4e-58 196.7 1.2 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KXS99467.1 - 1.2e-43 148.8 0.0 8.9e-43 145.9 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXS99467.1 - 9.1e-09 35.0 0.0 2.3e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KXS99467.1 - 1.2e-06 28.6 0.0 5.2e-06 26.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXS99467.1 - 1.2e-05 25.7 2.0 0.00022 21.7 2.0 3.1 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 KXS99467.1 - 1.8e-05 24.2 0.0 0.00012 21.4 0.0 2.1 2 0 0 2 2 2 1 TIP49 P-loop domain RuvB_N PF05496.12 KXS99467.1 - 0.00016 21.5 0.0 0.00051 19.8 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KXS99467.1 - 0.00067 19.9 0.1 0.064 13.5 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KXS99467.1 - 0.0053 16.9 0.1 0.018 15.2 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_2 PF07724.14 KXS99467.1 - 0.0063 16.6 0.0 0.033 14.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 KXS99467.1 - 0.0093 15.7 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KXS99467.1 - 0.027 13.9 1.2 0.054 12.9 0.2 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI GHMP_kinases_C PF08544.13 KXS99467.1 - 0.031 14.6 0.0 0.63 10.4 0.0 2.8 2 0 0 2 2 2 0 GHMP kinases C terminal AAA_25 PF13481.6 KXS99467.1 - 0.035 13.7 1.3 0.47 10.0 0.3 2.5 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.6 KXS99467.1 - 0.062 13.9 0.1 0.26 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KXS99467.1 - 0.07 13.4 0.2 0.21 11.8 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 KXS99467.1 - 0.076 12.5 0.1 0.38 10.3 0.1 2.0 1 1 0 1 1 1 0 P-loop containing dynein motor region Peptidase_M50B PF13398.6 KXS99467.1 - 0.085 12.5 0.1 0.18 11.4 0.1 1.5 1 0 0 1 1 1 0 Peptidase M50B-like Beta_protein PF14350.6 KXS99467.1 - 0.11 11.9 0.1 0.34 10.3 0.0 1.7 2 0 0 2 2 2 0 Beta protein NACHT PF05729.12 KXS99467.1 - 0.12 12.3 0.4 2 8.3 0.1 2.4 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 KXS99467.1 - 0.15 12.1 0.0 0.39 10.7 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 KXS99467.1 - 0.16 11.3 1.6 1.4 8.2 0.0 2.6 3 0 0 3 3 3 0 KaiC WD40 PF00400.32 KXS99468.1 - 2e-26 91.7 25.3 3.9e-05 24.3 0.1 7.8 8 0 0 8 8 8 5 WD domain, G-beta repeat F-box-like PF12937.7 KXS99468.1 - 4e-12 45.8 0.1 9.2e-12 44.7 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXS99468.1 - 4.1e-10 39.3 0.0 1e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 KXS99468.1 - 5.5e-05 23.4 0.8 2.3 8.6 0.0 4.4 3 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXS99468.1 - 0.00043 19.1 0.2 1.3 7.6 0.0 3.2 3 0 0 3 3 3 2 Nucleoporin Nup120/160 WD40_like PF17005.5 KXS99468.1 - 0.033 13.5 0.7 2.1 7.6 0.1 2.8 2 1 0 3 3 3 0 WD40-like domain ECH_1 PF00378.20 KXS99469.1 - 1.1e-20 74.1 0.0 1.5e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXS99469.1 - 5.3e-08 32.7 0.0 8.3e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KXS99469.1 - 0.0026 17.7 0.0 1.3 9.0 0.0 2.3 2 0 0 2 2 2 2 Peptidase family S49 Abhydrolase_3 PF07859.13 KXS99470.1 - 1.3e-37 129.7 0.0 1.7e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXS99470.1 - 0.00022 21.9 0.0 0.00032 21.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.28 KXS99470.1 - 0.15 10.9 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 Carboxylesterase family Thioesterase PF00975.20 KXS99470.1 - 0.16 12.1 1.4 1.1 9.3 0.7 2.2 1 1 0 1 1 1 0 Thioesterase domain Thiamine_BP PF01910.17 KXS99471.1 - 6.2e-27 93.4 0.1 8.9e-27 92.9 0.1 1.2 1 0 0 1 1 1 1 Thiamine-binding protein Thiamine_BP PF01910.17 KXS99472.1 - 8.3e-31 105.8 0.0 1.1e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 Thiamine-binding protein DUF1335 PF07056.11 KXS99472.1 - 0.15 12.2 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1335) Thiamine_BP PF01910.17 KXS99473.1 - 6.2e-27 93.4 0.1 8.9e-27 92.9 0.1 1.2 1 0 0 1 1 1 1 Thiamine-binding protein Thiamine_BP PF01910.17 KXS99474.1 - 8.3e-31 105.8 0.0 1.1e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 Thiamine-binding protein DUF1335 PF07056.11 KXS99474.1 - 0.15 12.2 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1335) MCD_N PF17408.2 KXS99475.1 - 0.0044 17.1 0.3 0.0067 16.5 0.2 1.4 1 1 0 1 1 1 1 Malonyl-CoA decarboxylase N-terminal domain Fer4_24 PF18109.1 KXS99475.1 - 0.0088 16.3 1.1 0.92 9.8 0.2 3.3 3 0 0 3 3 3 1 Ferredoxin I 4Fe-4S cluster domain Ectatomin PF06457.11 KXS99475.1 - 0.019 14.8 8.0 42 4.2 0.0 6.4 3 2 5 8 8 8 0 Ectatomin Dynactin_p22 PF07426.11 KXS99475.1 - 0.051 13.4 3.6 0.12 12.2 3.5 1.7 1 1 0 1 1 1 0 Dynactin subunit p22 FLYWCH_u PF16662.5 KXS99475.1 - 0.16 12.0 0.1 1.7 8.7 0.1 2.7 1 1 1 2 2 2 0 FLYWCH-type zinc finger-containing protein 1 COMPASS-Shg1 PF05205.12 KXS99475.1 - 0.4 11.4 5.4 5.3 7.8 2.2 2.2 1 1 1 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 RuvA_C PF07499.13 KXS99475.1 - 0.44 11.0 11.0 31 5.1 0.4 5.0 1 1 5 6 6 6 0 RuvA, C-terminal domain DHHC PF01529.20 KXS99476.1 - 1.2e-25 90.1 8.8 1.8e-25 89.6 4.0 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase MerC PF03203.14 KXS99476.1 - 6.9 7.2 8.3 0.29 11.6 2.6 1.6 2 0 0 2 2 2 0 MerC mercury resistance protein Clathrin_lg_ch PF01086.17 KXS99478.1 - 3.2e-80 269.5 2.7 3.6e-80 269.3 2.7 1.0 1 0 0 1 1 1 1 Clathrin light chain EMP24_GP25L PF01105.24 KXS99478.1 - 0.062 13.2 0.4 0.087 12.8 0.4 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD rve_3 PF13683.6 KXS99478.1 - 0.16 11.8 0.3 0.33 10.8 0.3 1.5 1 0 0 1 1 1 0 Integrase core domain Put_DNA-bind_N PF06971.13 KXS99479.1 - 0.0081 16.2 0.0 0.027 14.5 0.0 1.9 2 0 0 2 2 2 1 Putative DNA-binding protein N-terminus CTD_bind PF04818.13 KXS99480.1 - 5.3e-18 65.6 0.4 1.2e-17 64.4 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase II-binding domain. DMPK_coil PF08826.10 KXS99480.1 - 0.006 16.7 2.9 0.006 16.7 2.9 3.1 3 0 0 3 3 3 1 DMPK coiled coil domain like PIN_9 PF18477.1 KXS99480.1 - 0.062 13.6 0.4 0.17 12.2 0.4 1.7 1 0 0 1 1 1 0 PIN like domain CREPT PF16566.5 KXS99480.1 - 0.064 13.4 0.5 0.064 13.4 0.5 2.0 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DUF3328 PF11807.8 KXS99481.1 - 5.2e-20 72.2 0.0 8.7e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) ABC_membrane PF00664.23 KXS99482.1 - 1.1e-48 166.3 12.4 1.7e-48 165.6 12.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KXS99482.1 - 5.3e-35 120.9 0.3 2.4e-34 118.8 0.0 2.3 3 0 0 3 3 3 1 ABC transporter SMC_N PF02463.19 KXS99482.1 - 0.00015 21.2 0.0 0.00034 20.1 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KXS99482.1 - 0.00075 19.9 0.0 0.00075 19.9 0.0 2.6 4 0 0 4 4 4 1 AAA ATPase domain DEAD PF00270.29 KXS99482.1 - 0.0033 17.2 0.0 0.029 14.2 0.0 2.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_25 PF13481.6 KXS99482.1 - 0.0036 16.9 0.1 0.017 14.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXS99482.1 - 0.005 16.6 0.8 0.014 15.1 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KXS99482.1 - 0.06 13.6 4.2 0.08 13.2 0.4 2.6 2 1 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 KXS99482.1 - 0.06 13.5 0.0 9.7 6.3 0.0 2.9 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF3987 PF13148.6 KXS99482.1 - 0.071 12.1 0.0 0.071 12.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_29 PF13555.6 KXS99482.1 - 0.099 12.4 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.6 KXS99482.1 - 0.14 12.4 0.5 1.5 9.1 0.5 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Coilin_N PF15862.5 KXS99482.1 - 0.86 9.4 5.1 1.8 8.3 0.6 2.4 2 0 0 2 2 2 0 Coilin N-terminus PrgI PF12666.7 KXS99482.1 - 2.4 8.9 5.1 2.5 8.9 0.1 2.9 3 0 0 3 3 3 0 PrgI family protein Methyltransf_23 PF13489.6 KXS99483.1 - 3.9e-21 75.6 0.0 1.2e-20 74.0 0.0 1.5 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS99483.1 - 9.3e-21 74.3 0.0 1.9e-20 73.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXS99483.1 - 4.2e-17 62.6 0.0 8.3e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS99483.1 - 7.8e-17 61.8 0.0 1.9e-16 60.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS99483.1 - 3.3e-15 56.2 0.0 4.8e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KXS99483.1 - 1e-06 28.0 0.0 1.7e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) NodS PF05401.11 KXS99483.1 - 5.8e-06 26.1 0.0 9.3e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) PrmA PF06325.13 KXS99483.1 - 6e-06 25.9 0.0 8.5e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 KXS99483.1 - 7.5e-06 25.4 0.0 1.1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 KXS99483.1 - 8.3e-05 22.0 0.0 0.00013 21.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KXS99483.1 - 0.00061 19.4 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 KXS99483.1 - 0.0088 16.0 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Trp_leader2 PF08056.11 KXS99483.1 - 0.028 14.4 0.5 0.073 13.1 0.5 1.7 1 0 0 1 1 1 0 Tryptophan operon leader peptide PCMT PF01135.19 KXS99483.1 - 0.21 11.3 0.0 0.34 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PI-PLC-X PF00388.19 KXS99484.1 - 0.00023 20.8 0.0 0.0004 20.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain DUF3602 PF12223.8 KXS99484.1 - 0.06 13.9 0.3 0.15 12.7 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3602) ApbA_C PF08546.11 KXS99485.1 - 1.9e-27 95.9 0.0 2.7e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KXS99485.1 - 3.7e-27 94.9 0.0 4.9e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KXS99486.1 - 1.9e-27 95.9 0.0 2.7e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KXS99486.1 - 3.7e-27 94.9 0.0 4.9e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA FMN_dh PF01070.18 KXS99487.1 - 2.1e-116 388.7 0.0 2.5e-116 388.5 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KXS99487.1 - 1e-20 73.7 0.0 2e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KXS99487.1 - 2.9e-07 29.9 0.0 5.7e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KXS99487.1 - 2.2e-06 27.0 1.5 1.9e-05 23.9 0.5 2.4 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 KXS99487.1 - 0.0084 15.4 0.0 1.5 8.1 0.0 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 KXS99487.1 - 0.016 14.7 0.5 0.45 9.9 0.0 2.7 3 0 0 3 3 3 0 Histidine biosynthesis protein NMO PF03060.15 KXS99487.1 - 0.022 14.1 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase ADH_N PF08240.12 KXS99488.1 - 3.9e-22 78.2 6.8 6.1e-22 77.6 6.8 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXS99488.1 - 5.9e-19 68.3 0.1 1.3e-18 67.3 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXS99488.1 - 4e-06 27.9 0.0 8.2e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KXS99488.1 - 0.0012 18.3 0.4 0.0019 17.6 0.4 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KXS99488.1 - 0.0071 15.7 0.1 0.014 14.7 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Ins_P5_2-kin PF06090.12 KXS99490.1 - 6.1e-44 150.8 0.1 9.8e-44 150.1 0.1 1.3 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase MCD_N PF17408.2 KXS99490.1 - 1.9 8.7 4.6 1 9.5 0.1 2.6 3 0 0 3 3 3 0 Malonyl-CoA decarboxylase N-terminal domain Zn_clus PF00172.18 KXS99491.1 - 3.4e-08 33.5 10.6 5.7e-08 32.7 10.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXS99491.1 - 0.00014 20.9 0.6 0.00025 20.0 0.2 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain PH_10 PF15411.6 KXS99492.1 - 1.1e-37 129.0 0.1 3.2e-37 127.5 0.1 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain CDC24 PF06395.11 KXS99492.1 - 5.3e-32 109.9 0.0 1.3e-31 108.7 0.0 1.7 1 0 0 1 1 1 1 CDC24 Calponin RhoGEF PF00621.20 KXS99492.1 - 1e-29 104.1 0.6 1.6e-29 103.4 0.6 1.3 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.24 KXS99492.1 - 7e-09 35.5 0.0 1.5e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 PB1 domain PH PF00169.29 KXS99492.1 - 0.0049 17.4 0.1 0.012 16.2 0.1 1.7 1 0 0 1 1 1 1 PH domain MFS_1 PF07690.16 KXS99493.1 - 4.1e-42 144.4 60.9 4.1e-42 144.4 60.9 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Neurensin PF14927.6 KXS99493.1 - 1.7 8.4 4.2 8.7 6.1 0.0 3.7 3 1 0 3 3 3 0 Neurensin HET PF06985.11 KXS99494.1 - 1.1e-32 113.4 0.1 2.4e-32 112.3 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) BTB PF00651.31 KXS99495.1 - 4.7e-11 42.9 1.0 2.8e-09 37.2 0.1 3.0 2 1 1 3 3 3 1 BTB/POZ domain BTB PF00651.31 KXS99496.1 - 4.7e-11 42.9 1.0 2.8e-09 37.2 0.1 3.0 2 1 1 3 3 3 1 BTB/POZ domain Velvet PF11754.8 KXS99497.1 - 2.1e-06 27.9 1.1 4.8e-06 26.7 1.1 1.6 1 1 0 1 1 1 1 Velvet factor Apt1 PF10351.9 KXS99497.1 - 0.018 13.9 1.3 0.021 13.7 1.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 KXS99497.1 - 0.062 12.1 0.0 0.082 11.7 0.0 1.1 1 0 0 1 1 1 0 Presenilin PUL PF08324.11 KXS99498.1 - 6.6e-40 137.1 0.6 8.7e-40 136.7 0.6 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 KXS99498.1 - 1e-39 135.2 0.1 1.9e-39 134.4 0.1 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 KXS99498.1 - 9.9e-36 121.2 9.4 2.5e-07 31.3 0.0 7.1 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.8 KXS99498.1 - 0.013 14.1 0.1 0.95 8.0 0.0 2.9 3 0 0 3 3 3 0 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KXS99498.1 - 0.038 14.3 0.1 44 4.5 0.0 4.1 4 1 1 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain Ish1 PF10281.9 KXS99499.1 - 4.1e-59 196.6 19.3 1.5e-14 54.0 0.2 5.4 5 0 0 5 5 5 5 Putative stress-responsive nuclear envelope protein HeH PF12949.7 KXS99499.1 - 1e-09 37.9 0.0 0.83 9.4 0.0 4.5 4 0 0 4 4 4 4 HeH/LEM domain SAP PF02037.27 KXS99499.1 - 0.0003 20.5 0.0 0.47 10.3 0.0 4.2 4 0 0 4 4 4 1 SAP domain Slx4 PF09494.10 KXS99499.1 - 0.0024 17.8 1.0 3.7 7.6 0.0 3.6 4 1 0 4 4 4 2 Slx4 endonuclease Apolipoprotein PF01442.18 KXS99499.1 - 0.13 12.1 0.0 0.13 12.1 0.0 3.3 2 1 0 3 3 3 0 Apolipoprotein A1/A4/E domain SAM_2 PF07647.17 KXS99499.1 - 5.2 7.3 7.3 51 4.1 0.0 4.0 5 0 0 5 5 5 0 SAM domain (Sterile alpha motif) Rad9 PF04139.13 KXS99500.1 - 2.6e-51 174.5 0.5 3.4e-51 174.1 0.5 1.1 1 0 0 1 1 1 1 Rad9 Ripply PF14998.6 KXS99500.1 - 0.14 12.8 0.0 0.35 11.5 0.0 1.8 1 0 0 1 1 1 0 Transcription Regulator RCC1 PF00415.18 KXS99501.1 - 2.3e-31 108.2 18.2 5.3e-09 36.6 0.2 6.4 5 1 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KXS99501.1 - 1.2e-25 88.7 27.1 2.5e-08 33.5 0.3 6.0 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat Methyltranf_PUA PF13636.6 KXS99501.1 - 0.021 14.8 0.2 2.4 8.2 0.0 2.6 2 0 0 2 2 2 0 RNA-binding PUA-like domain of methyltransferase RsmF Arf PF00025.21 KXS99502.1 - 1.5e-75 252.5 0.1 1.7e-75 252.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KXS99502.1 - 1.1e-14 54.6 0.0 1.5e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KXS99502.1 - 2e-13 50.1 0.0 2.9e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KXS99502.1 - 3.2e-13 49.6 0.0 3.8e-13 49.4 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KXS99502.1 - 1.2e-10 41.1 0.6 1.4e-06 27.7 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KXS99502.1 - 8.1e-09 35.2 0.0 1.1e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KXS99502.1 - 7.3e-07 29.3 0.0 1.2e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KXS99502.1 - 0.00023 20.8 0.0 0.02 14.4 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KXS99502.1 - 0.003 17.1 1.1 0.014 14.9 1.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B Toprim_4 PF13662.6 KXS99502.1 - 0.022 15.2 0.0 0.51 10.9 0.0 2.1 2 0 0 2 2 2 0 Toprim domain cobW PF02492.19 KXS99502.1 - 0.12 11.9 0.1 2.5 7.6 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain HicA_toxin PF07927.12 KXS99504.1 - 1.1e-05 25.4 0.0 2.3e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, Lipase_3 PF01764.25 KXS99505.1 - 2.6e-05 24.1 0.0 6.9e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 KXS99505.1 - 0.013 15.2 0.0 0.079 12.7 0.0 2.0 2 0 0 2 2 2 0 PGAP1-like protein Hydrolase_4 PF12146.8 KXS99505.1 - 0.046 13.0 0.0 0.081 12.2 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXS99505.1 - 0.076 12.6 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 KXS99505.1 - 0.091 12.5 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family HicB-like_2 PF15970.5 KXS99506.1 - 0.17 12.1 0.0 1.3 9.2 0.0 2.2 2 0 0 2 2 2 0 HicB_like antitoxin of bacterial toxin-antitoxin system Phos_pyr_kin PF08543.12 KXS99507.1 - 3.6e-78 262.3 6.6 5.2e-78 261.8 6.6 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 KXS99507.1 - 2.6e-51 174.4 0.7 4e-51 173.8 0.7 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.24 KXS99507.1 - 3.1e-06 26.7 0.4 1.4e-05 24.6 0.4 1.9 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Carb_kinase PF01256.17 KXS99507.1 - 0.04 13.4 5.0 0.11 12.0 2.0 2.5 2 1 0 2 2 2 0 Carbohydrate kinase HK PF02110.15 KXS99507.1 - 0.93 8.8 7.3 1.3 8.3 4.7 2.4 1 1 1 2 2 2 0 Hydroxyethylthiazole kinase family Phos_pyr_kin PF08543.12 KXS99508.1 - 4.1e-78 262.2 6.6 5.9e-78 261.6 6.6 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 KXS99508.1 - 2.8e-51 174.3 0.7 4.4e-51 173.7 0.7 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.24 KXS99508.1 - 3.6e-06 26.5 0.4 1.5e-05 24.4 0.4 1.9 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Carb_kinase PF01256.17 KXS99508.1 - 0.046 13.2 5.0 0.12 11.9 2.0 2.5 2 1 0 2 2 2 0 Carbohydrate kinase HK PF02110.15 KXS99508.1 - 0.83 9.0 6.9 1.4 8.3 4.7 2.4 1 1 1 2 2 2 0 Hydroxyethylthiazole kinase family LRR_8 PF13855.6 KXS99509.1 - 0.76 9.6 15.4 4.7 7.1 0.0 6.3 7 0 0 7 7 7 0 Leucine rich repeat LRR_8 PF13855.6 KXS99510.1 - 0.76 9.6 15.4 4.7 7.1 0.0 6.3 7 0 0 7 7 7 0 Leucine rich repeat Ferric_reduct PF01794.19 KXS99512.1 - 1.2e-19 70.6 17.9 1.2e-19 70.6 17.9 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KXS99512.1 - 1.5e-08 34.9 0.0 8.4e-07 29.2 0.0 2.4 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KXS99512.1 - 1e-05 25.6 0.0 0.18 11.9 0.0 2.5 2 0 0 2 2 2 2 FAD-binding domain CFEM PF05730.11 KXS99513.1 - 1.4 9.1 10.3 0.14 12.3 4.9 2.1 2 1 0 2 2 2 0 CFEM domain CFEM PF05730.11 KXS99514.1 - 1.3 9.2 10.5 0.14 12.3 5.0 2.2 2 1 0 2 2 2 0 CFEM domain CFEM PF05730.11 KXS99515.1 - 1.3 9.2 10.5 0.14 12.3 5.0 2.2 2 1 0 2 2 2 0 CFEM domain AMP-binding_C_2 PF14535.6 KXS99516.1 - 0.047 14.0 0.2 0.079 13.3 0.2 1.3 1 1 0 1 1 1 0 AMP-binding enzyme C-terminal domain AAA PF00004.29 KXS99517.1 - 4.3e-40 137.2 0.0 9.1e-40 136.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KXS99517.1 - 1.4e-19 69.8 0.2 2.9e-19 68.8 0.2 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KXS99517.1 - 6.6e-07 29.0 0.0 1.5e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KXS99517.1 - 0.00012 22.5 1.4 0.015 15.7 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 KXS99517.1 - 0.00017 21.6 0.5 0.00073 19.6 0.1 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KXS99517.1 - 0.00025 20.8 0.0 0.00068 19.4 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KXS99517.1 - 0.0019 18.3 1.4 0.013 15.7 0.0 2.9 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) PhoH PF02562.16 KXS99517.1 - 0.005 16.3 0.2 0.072 12.5 0.1 2.3 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 KXS99517.1 - 0.0071 15.7 0.1 0.02 14.3 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 KXS99517.1 - 0.01 15.0 0.0 0.025 13.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 KXS99517.1 - 0.011 15.9 0.0 0.036 14.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain JIP_LZII PF16471.5 KXS99517.1 - 0.012 15.8 3.7 0.035 14.3 3.7 1.8 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II AAA_22 PF13401.6 KXS99517.1 - 0.022 15.0 5.8 0.084 13.1 0.0 3.2 3 1 1 4 4 4 0 AAA domain IstB_IS21 PF01695.17 KXS99517.1 - 0.068 12.9 0.1 0.16 11.7 0.1 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 KXS99517.1 - 0.12 11.9 0.2 0.49 9.9 0.0 2.1 2 1 0 2 2 2 0 P-loop containing dynein motor region AAA_11 PF13086.6 KXS99517.1 - 0.24 11.1 8.7 0.38 10.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain RPN2_C PF18004.1 KXS99517.1 - 1.6 8.7 10.9 3.6 7.5 10.9 1.6 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Bac_surface_Ag PF01103.23 KXS99518.1 - 4.5e-41 141.4 0.1 5.6e-41 141.1 0.1 1.1 1 0 0 1 1 1 1 Surface antigen Peripla_BP_2 PF01497.18 KXS99518.1 - 0.04 13.5 0.0 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein DUF1400 PF07176.11 KXS99518.1 - 0.11 12.8 0.2 0.22 11.8 0.2 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1400) Rep_1 PF01446.17 KXS99518.1 - 0.21 11.0 0.0 0.38 10.2 0.0 1.3 1 0 0 1 1 1 0 Replication protein UPF0669 PF17065.5 KXS99519.1 - 0.032 14.0 0.0 0.044 13.5 0.0 1.2 1 1 0 1 1 1 0 Putative cytokine, C6ORF120 MAP1B_neuraxin PF00414.17 KXS99519.1 - 0.087 12.4 0.5 0.087 12.4 0.5 2.4 2 0 0 2 2 2 0 Neuraxin and MAP1B repeat COesterase PF00135.28 KXS99521.1 - 0.11 11.4 0.1 0.43 9.4 0.0 1.9 2 0 0 2 2 2 0 Carboxylesterase family C_LFY_FLO PF17538.2 KXS99521.1 - 0.16 11.5 0.1 0.23 10.9 0.1 1.2 1 0 0 1 1 1 0 DNA Binding Domain (C-terminal) Leafy/Floricaula Sigma54_CBD PF04963.13 KXS99522.1 - 0.16 11.8 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain RIG-I_C PF18119.1 KXS99523.1 - 0.099 12.7 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 RIG-I receptor C-terminal domain Bac_rhamnosid6H PF17389.2 KXS99524.1 - 1.8e-10 40.6 0.1 2.8e-08 33.4 0.1 2.2 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Trehalase PF01204.18 KXS99524.1 - 0.00047 19.1 0.1 0.00066 18.6 0.1 1.1 1 0 0 1 1 1 1 Trehalase Mersacidin PF16934.5 KXS99524.1 - 0.064 13.0 1.4 0.21 11.4 1.4 1.9 1 0 0 1 1 1 0 Two-component Enterococcus faecalis cytolysin (EFC) zf-C2H2 PF00096.26 KXS99530.1 - 0.22 12.0 0.2 0.48 11.0 0.2 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type DFRP_C PF16543.5 KXS99530.1 - 0.37 11.3 7.5 0.17 12.4 4.6 1.8 2 0 0 2 2 2 0 DRG Family Regulatory Proteins, Tma46 DUF1682 PF07946.14 KXS99530.1 - 1.4 8.0 7.9 2.1 7.4 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) zf-C2H2 PF00096.26 KXS99531.1 - 0.15 12.6 0.2 0.36 11.4 0.2 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF1387 PF07139.11 KXS99531.1 - 0.94 9.2 3.6 9.7 5.8 4.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) zf-C2H2 PF00096.26 KXS99532.1 - 0.24 12.0 0.2 0.51 10.9 0.2 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF1387 PF07139.11 KXS99532.1 - 0.28 10.9 13.7 0.14 11.9 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) DFRP_C PF16543.5 KXS99532.1 - 0.7 10.4 8.3 0.19 12.3 4.6 1.8 2 0 0 2 2 2 0 DRG Family Regulatory Proteins, Tma46 DUF1682 PF07946.14 KXS99532.1 - 1.6 7.9 7.9 2.3 7.3 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF1682 PF07946.14 KXS99533.1 - 2.1 7.5 11.2 2.7 7.1 11.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF1387 PF07139.11 KXS99534.1 - 0.079 12.7 12.7 0.1 12.3 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) zf-C2H2 PF00096.26 KXS99534.1 - 0.21 12.1 0.2 0.47 11.0 0.2 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type DFRP_C PF16543.5 KXS99534.1 - 0.39 11.2 7.6 0.17 12.4 4.6 1.8 2 0 0 2 2 2 0 DRG Family Regulatory Proteins, Tma46 DUF1682 PF07946.14 KXS99534.1 - 1.4 8.1 7.9 2.1 7.5 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) zf-C2H2 PF00096.26 KXS99535.1 - 0.13 12.7 0.2 0.32 11.5 0.2 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF1387 PF07139.11 KXS99535.1 - 0.78 9.4 4.2 8.7 6.0 5.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) TFIIA PF03153.13 KXS99535.1 - 6.1 6.7 20.0 7.1 6.5 20.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1682 PF07946.14 KXS99536.1 - 2.1 7.5 11.2 2.7 7.1 11.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) PDH PF02153.17 KXS99538.1 - 7.1e-16 58.0 0.1 1.2e-15 57.2 0.1 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 KXS99538.1 - 0.00011 22.7 0.1 0.0011 19.5 0.1 2.5 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KXS99538.1 - 0.0039 17.4 0.4 0.012 15.8 0.4 1.9 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KXS99538.1 - 0.014 15.3 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KXS99538.1 - 0.045 13.1 0.0 0.074 12.4 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PDH PF02153.17 KXS99539.1 - 6.1e-16 58.2 0.0 1e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 KXS99539.1 - 3.8e-05 24.2 0.1 0.00031 21.2 0.1 2.5 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KXS99539.1 - 0.0021 18.3 0.2 0.0052 17.0 0.2 1.7 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 KXS99539.1 - 0.044 13.1 0.0 0.072 12.4 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KXS99539.1 - 0.088 12.7 0.1 0.17 11.8 0.1 1.6 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain bZIP_1 PF00170.21 KXS99540.1 - 0.0049 16.9 11.2 0.011 15.9 11.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXS99540.1 - 0.011 15.8 15.5 0.025 14.7 15.5 1.6 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_Maf PF03131.17 KXS99540.1 - 3.9 8.1 14.0 0.27 11.8 8.1 2.0 2 0 0 2 2 2 0 bZIP Maf transcription factor adh_short_C2 PF13561.6 KXS99541.1 - 6.5e-49 166.6 0.2 7.4e-49 166.4 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS99541.1 - 2.3e-47 161.0 0.2 2.9e-47 160.7 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXS99541.1 - 4.3e-10 39.8 0.4 6.2e-10 39.3 0.4 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXS99541.1 - 0.00022 20.8 0.1 0.0004 19.9 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXS99541.1 - 0.00023 20.7 0.0 0.00042 19.8 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KXS99541.1 - 0.0066 16.4 0.0 0.0097 15.8 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KXS99541.1 - 0.012 14.7 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Hydantoinase_A PF01968.18 KXS99541.1 - 0.051 12.8 0.2 0.08 12.2 0.2 1.2 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase Amidohydro_1 PF01979.20 KXS99542.1 - 1.9e-74 251.1 0.0 2.2e-74 250.8 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXS99542.1 - 1.5e-14 54.3 0.4 2.9e-12 46.8 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family DCAF15_WD40 PF14939.6 KXS99542.1 - 0.013 15.2 0.1 0.02 14.5 0.1 1.3 1 0 0 1 1 1 0 DDB1-and CUL4-substrate receptor 15, WD repeat A_deaminase PF00962.22 KXS99542.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Adenosine/AMP deaminase Ala_racemase_N PF01168.20 KXS99543.1 - 8.9e-26 90.9 0.1 1.1e-25 90.6 0.1 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain VPS9 PF02204.18 KXS99544.1 - 2.9e-24 85.3 0.0 5.6e-24 84.4 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 KXS99544.1 - 0.016 15.5 0.1 0.071 13.4 0.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF5601) NAD_binding_10 PF13460.6 KXS99545.1 - 3.1e-13 50.0 0.0 7.5e-12 45.5 0.0 2.0 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXS99545.1 - 1.9e-05 24.3 0.0 2.6e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KXS99545.1 - 0.0076 15.7 0.0 0.0098 15.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 KXS99545.1 - 0.015 14.7 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase YopX PF09643.10 KXS99547.1 - 0.023 14.8 0.0 0.026 14.6 0.0 1.2 1 0 0 1 1 1 0 YopX protein MAPEG PF01124.18 KXS99548.1 - 8.7e-15 54.8 1.9 1.1e-14 54.4 1.9 1.2 1 0 0 1 1 1 1 MAPEG family UQ_con PF00179.26 KXS99549.1 - 1.1e-19 70.5 0.0 1.9e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXS99549.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family B DUF2514 PF10721.9 KXS99549.1 - 0.64 10.0 9.2 0.37 10.8 7.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) DUF4574 PF15141.6 KXS99550.1 - 0.16 11.9 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 Ribosomal_S11 PF00411.19 KXS99551.1 - 7.6e-46 155.1 1.4 1.2e-45 154.4 1.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S11 SMC_Nse1 PF07574.13 KXS99553.1 - 7.2e-62 208.7 1.4 9e-62 208.4 1.4 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 KXS99553.1 - 5.9e-13 48.9 10.8 1.1e-12 48.0 10.8 1.5 1 0 0 1 1 1 1 RING-like domain zf-ANAPC11 PF12861.7 KXS99553.1 - 0.00011 22.2 1.7 0.0002 21.3 1.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger HTH_IclR PF09339.10 KXS99553.1 - 0.0067 16.2 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain CtsR_C PF17727.1 KXS99553.1 - 0.012 15.7 0.1 4.7 7.4 0.0 3.2 2 1 1 3 3 3 0 CtsR C-terminal dimerization domain zf-RING_2 PF13639.6 KXS99553.1 - 0.019 15.3 7.1 0.043 14.2 7.1 1.6 1 0 0 1 1 1 0 Ring finger domain TetR PF13972.6 KXS99553.1 - 0.047 13.4 0.1 0.16 11.7 0.1 1.8 2 0 0 2 2 2 0 Bacterial transcriptional repressor FANCL_C PF11793.8 KXS99553.1 - 0.099 12.8 4.5 0.21 11.8 4.5 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain RIH_assoc PF08454.11 KXS99553.1 - 0.15 11.9 1.3 8.8 6.3 0.0 2.5 2 0 0 2 2 2 0 RyR and IP3R Homology associated zf-HC5HC2H PF13771.6 KXS99553.1 - 2.5 8.4 9.3 11 6.4 9.4 1.9 1 1 1 2 2 2 0 PHD-like zinc-binding domain C1_1 PF00130.22 KXS99553.1 - 3 7.8 10.7 0.3 11.0 5.0 2.1 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4 PF00097.25 KXS99553.1 - 3.1 7.8 7.6 7 6.6 7.6 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SET PF00856.28 KXS99555.1 - 3.9e-10 40.4 0.0 2.3e-09 37.9 0.0 2.1 1 1 0 1 1 1 1 SET domain RmlD_sub_bind PF04321.17 KXS99563.1 - 7.4e-17 61.4 0.0 1e-16 60.9 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 KXS99563.1 - 6e-13 48.8 0.0 8.1e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXS99563.1 - 0.0012 18.3 0.0 0.0038 16.7 0.0 1.7 1 1 1 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KXS99563.1 - 0.034 13.3 0.0 0.055 12.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein FR47 PF08445.10 KXS99564.1 - 0.002 18.0 0.0 0.006 16.5 0.0 1.9 1 1 0 1 1 1 1 FR47-like protein zf-C2H2 PF00096.26 KXS99565.1 - 4e-10 39.6 11.5 1.4e-05 25.2 4.4 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXS99565.1 - 7.7e-09 35.6 15.8 4e-05 23.9 0.4 3.3 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXS99565.1 - 4.4e-07 30.2 10.4 0.00061 20.4 2.9 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KXS99565.1 - 6.6e-06 26.3 1.2 1.8e-05 24.9 1.2 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KXS99565.1 - 0.00011 22.0 8.1 0.00014 21.8 2.1 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXS99565.1 - 0.00084 19.6 5.0 0.001 19.3 2.5 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KXS99565.1 - 0.12 12.3 4.5 3.6 7.6 0.3 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.7 KXS99565.1 - 0.15 12.4 2.8 0.16 12.3 1.6 1.7 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 KXS99565.1 - 0.33 10.8 9.0 1.3 8.8 1.0 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-BED PF02892.15 KXS99565.1 - 1.6 8.8 4.9 0.91 9.6 0.9 2.2 2 0 0 2 2 2 0 BED zinc finger Peptidase_S8 PF00082.22 KXS99566.1 - 7.7e-36 123.9 0.7 7.7e-36 123.9 0.7 1.5 2 0 0 2 2 2 1 Subtilase family P_proprotein PF01483.20 KXS99566.1 - 2.7e-27 94.6 0.6 2.7e-27 94.6 0.6 1.8 2 0 0 2 2 2 1 Proprotein convertase P-domain BDHCT_assoc PF16204.5 KXS99566.1 - 1.9 8.1 4.5 1.9 8.2 2.1 2.0 2 0 0 2 2 2 0 BDHCT-box associated domain on Bloom syndrome protein DUF3807 PF12720.7 KXS99567.1 - 3e-23 83.0 5.1 3e-23 83.0 5.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3807) DUF3807 PF12720.7 KXS99568.1 - 3e-23 83.0 5.1 3e-23 83.0 5.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3807) Thioredoxin PF00085.20 KXS99569.1 - 1.1e-34 118.4 1.1 6.3e-28 96.8 0.1 2.9 3 0 0 3 3 3 2 Thioredoxin OST3_OST6 PF04756.13 KXS99569.1 - 8.3e-08 31.9 0.0 2.9e-06 26.9 0.0 2.2 1 1 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 KXS99569.1 - 1.3e-07 32.1 0.3 0.0042 17.5 0.0 2.8 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin_6 PF13848.6 KXS99569.1 - 5e-06 26.5 0.0 0.0035 17.3 0.0 3.3 2 1 2 4 4 4 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KXS99569.1 - 8.5e-05 22.8 0.3 3.2 8.2 0.0 4.6 3 2 1 4 4 4 1 Thioredoxin-like AhpC-TSA PF00578.21 KXS99569.1 - 0.00025 21.0 0.1 0.012 15.5 0.0 2.7 3 0 0 3 3 3 1 AhpC/TSA family ERp29_N PF07912.13 KXS99569.1 - 0.00058 20.0 0.0 0.017 15.2 0.0 2.3 2 0 0 2 2 2 1 ERp29, N-terminal domain Thioredoxin_7 PF13899.6 KXS99569.1 - 0.0052 16.9 0.0 0.014 15.6 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like TraF PF13728.6 KXS99569.1 - 0.0075 16.1 0.0 0.0075 16.1 0.0 4.2 5 0 0 5 5 5 1 F plasmid transfer operon protein SpoIIIAH PF12685.7 KXS99569.1 - 0.12 12.2 1.8 0.25 11.2 1.8 1.5 1 0 0 1 1 1 0 SpoIIIAH-like protein Med21 PF11221.8 KXS99569.1 - 0.39 11.0 4.7 1 9.6 4.7 1.7 1 0 0 1 1 1 0 Subunit 21 of Mediator complex Mitofilin PF09731.9 KXS99569.1 - 1.8 7.3 11.6 1.6 7.5 10.6 1.4 1 1 0 1 1 1 0 Mitochondrial inner membrane protein Ran_BP1 PF00638.18 KXS99570.1 - 7.3e-13 48.8 0.0 1.2e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 RanBP1 domain Sel1 PF08238.12 KXS99571.1 - 2.9e-11 43.7 9.6 1.6e-05 25.4 0.3 3.9 4 0 0 4 4 4 3 Sel1 repeat Cytotoxic PF09000.10 KXS99571.1 - 0.63 10.4 4.5 6.1 7.3 0.0 2.6 2 0 0 2 2 2 0 Cytotoxic ABC2_membrane PF01061.24 KXS99573.1 - 4e-78 261.6 47.3 5.5e-45 153.4 14.6 2.7 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.27 KXS99573.1 - 1.2e-38 132.8 0.1 7.6e-19 68.6 0.0 2.7 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KXS99573.1 - 8.3e-24 83.3 0.8 2.9e-21 75.2 0.2 2.9 2 0 0 2 2 2 1 CDR ABC transporter ABC_trans_N PF14510.6 KXS99573.1 - 3.2e-12 46.9 0.2 9.1e-12 45.4 0.2 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 KXS99573.1 - 8.2e-07 28.4 31.9 0.0016 17.6 16.0 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.6 KXS99573.1 - 3.4e-05 24.3 0.2 0.016 15.6 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KXS99573.1 - 6e-05 23.3 0.5 0.5 10.6 0.2 3.7 3 2 1 4 4 3 2 AAA domain AAA_25 PF13481.6 KXS99573.1 - 0.00016 21.3 0.2 0.0024 17.5 0.1 2.2 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KXS99573.1 - 0.00022 21.2 0.2 0.01 15.7 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 KXS99573.1 - 0.001 19.0 0.1 4.3 7.1 0.0 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXS99573.1 - 0.01 15.6 0.3 0.089 12.5 0.1 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain PduV-EutP PF10662.9 KXS99573.1 - 0.026 14.2 0.8 7.8 6.2 0.3 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 KXS99573.1 - 0.052 13.1 1.0 1.1 8.8 0.4 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 KXS99573.1 - 0.064 13.7 0.0 12 6.4 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KXS99573.1 - 0.068 13.4 1.9 0.96 9.7 0.4 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KXS99573.1 - 0.083 13.4 0.0 5.4 7.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KXS99573.1 - 0.14 12.1 0.6 1.2 9.0 0.2 2.2 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.23 KXS99573.1 - 0.16 12.0 0.2 22 5.2 0.1 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Cas_APE2256 PF09651.10 KXS99573.1 - 0.17 11.7 0.0 0.37 10.7 0.0 1.4 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_APE2256) DUF1295 PF06966.12 KXS99575.1 - 9.2e-54 182.4 0.9 1.4e-53 181.9 0.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 KXS99575.1 - 9.3e-05 22.8 1.6 0.00011 22.5 0.1 2.1 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.16 KXS99575.1 - 0.0013 18.7 1.7 0.0048 16.9 0.2 2.5 2 2 1 3 3 3 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 KXS99575.1 - 0.022 15.2 2.1 0.22 11.9 0.0 2.8 2 1 1 3 3 3 0 Phospholipid methyltransferase PepX_N PF09168.10 KXS99575.1 - 0.15 12.5 0.2 0.24 11.8 0.2 1.2 1 0 0 1 1 1 0 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal APG6 PF04111.12 KXS99576.1 - 1.5e-71 240.0 0.0 2.2e-71 239.5 0.0 1.2 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 KXS99576.1 - 1.1e-35 123.0 22.5 1.9e-35 122.3 22.5 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region SUKH-4 PF14435.6 KXS99576.1 - 0.039 14.0 2.5 0.12 12.4 2.5 1.8 2 0 0 2 2 2 0 SUKH-4 immunity protein DUF1664 PF07889.12 KXS99576.1 - 0.063 13.3 1.9 0.18 11.9 1.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) zf_UBZ PF18439.1 KXS99576.1 - 0.12 12.0 0.9 1.2 8.8 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger V_ATPase_I PF01496.19 KXS99576.1 - 0.45 8.4 3.9 0.61 7.9 3.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YabA PF06156.13 KXS99576.1 - 0.63 10.7 3.5 0.5 11.0 1.1 2.0 1 1 1 2 2 2 0 Initiation control protein YabA GAS PF13851.6 KXS99576.1 - 0.7 9.2 18.1 0.89 8.9 14.3 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding FapA PF03961.13 KXS99576.1 - 1.2 7.6 4.4 1.9 7.0 4.4 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A zf-C4H2 PF10146.9 KXS99576.1 - 3.9 7.7 13.8 1.8 8.8 11.4 1.6 1 1 0 1 1 1 0 Zinc finger-containing protein DUF3450 PF11932.8 KXS99576.1 - 4.7 6.5 16.1 1.2 8.4 11.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Glyoxalase PF00903.25 KXS99577.1 - 4.4e-06 26.9 0.0 4.9e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily GDP_Man_Dehyd PF16363.5 KXS99578.1 - 1.4e-60 205.5 0.2 8.8e-59 199.6 0.2 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KXS99578.1 - 1.8e-45 155.3 0.4 4.8e-44 150.6 0.4 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KXS99578.1 - 3.9e-17 62.3 0.0 6.3e-14 51.8 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 KXS99578.1 - 3.6e-16 59.2 0.0 3.7e-15 55.8 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KXS99578.1 - 3.3e-13 49.3 0.0 4.5e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KXS99578.1 - 4.4e-11 42.4 0.0 1.1e-10 41.1 0.0 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KXS99578.1 - 0.00021 21.3 0.0 0.00041 20.3 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding Ribosomal_L10 PF00466.20 KXS99579.1 - 3.8e-23 81.5 0.1 7.3e-23 80.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 KXS99579.1 - 2.1e-22 78.9 0.1 5.3e-22 77.6 0.0 1.7 2 0 0 2 2 2 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 KXS99579.1 - 4.2e-21 75.3 4.8 7.3e-21 74.6 1.8 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein RRN3 PF05327.11 KXS99580.1 - 0.078 11.5 0.7 0.11 11.0 0.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF4342 PF14242.6 KXS99580.1 - 0.2 11.7 0.2 0.37 10.8 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) F-box PF00646.33 KXS99581.1 - 0.00057 19.7 0.1 0.0011 18.8 0.1 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXS99581.1 - 0.017 15.0 0.0 0.038 13.9 0.0 1.6 1 0 0 1 1 1 0 F-box-like Vta1 PF04652.16 KXS99582.1 - 2.1e-53 180.2 3.8 1.6e-52 177.3 4.3 1.9 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 KXS99582.1 - 3e-16 58.8 0.3 7e-16 57.6 0.3 1.7 1 0 0 1 1 1 1 Vta1 C-terminal domain PALP PF00291.25 KXS99585.1 - 1.1e-62 212.1 0.8 1.4e-62 211.8 0.8 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Peptidase_S24 PF00717.23 KXS99586.1 - 3.1e-05 23.8 0.0 4.4e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like PhoD PF09423.10 KXS99587.1 - 1.2e-06 27.8 0.3 1e-05 24.7 0.3 2.1 1 1 0 1 1 1 1 PhoD-like phosphatase MTBP_mid PF14919.6 KXS99587.1 - 0.87 8.7 3.0 1.5 7.9 3.0 1.3 1 0 0 1 1 1 0 MDM2-binding DUF3328 PF11807.8 KXS99588.1 - 7.1e-48 163.3 0.8 9.1e-48 162.9 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3024 PF11225.8 KXS99588.1 - 0.1 12.9 1.1 0.66 10.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3024) adh_short PF00106.25 KXS99590.1 - 3.8e-28 98.3 3.2 4.9e-16 58.8 0.1 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXS99590.1 - 1.1e-24 87.3 3.0 9.4e-14 51.5 0.6 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KXS99590.1 - 4.1e-05 23.2 0.2 7.3e-05 22.4 0.2 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KXS99590.1 - 0.016 15.2 0.3 0.044 13.7 0.3 1.7 1 0 0 1 1 1 0 KR domain Sacchrp_dh_NADP PF03435.18 KXS99590.1 - 0.091 13.0 0.2 0.23 11.7 0.2 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TPT PF03151.16 KXS99591.1 - 7.1e-10 38.7 18.8 9.6e-10 38.3 18.8 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KXS99591.1 - 7.6e-08 32.6 28.7 8.6e-08 32.4 10.8 2.2 2 0 0 2 2 2 2 EamA-like transporter family TRI9 PF08195.11 KXS99591.1 - 0.033 14.1 0.4 0.35 10.8 0.2 2.4 2 0 0 2 2 2 0 TRI9 protein MitoNEET_N PF10660.9 KXS99591.1 - 6 7.0 11.3 2.9 8.0 0.0 3.7 3 2 1 4 4 4 0 Iron-containing outer mitochondrial membrane protein N-terminus MFS_1 PF07690.16 KXS99593.1 - 5.5e-52 176.8 20.2 1e-49 169.3 15.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS99593.1 - 1.7e-12 47.0 25.0 3.9e-11 42.5 25.0 2.9 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 KXS99593.1 - 0.00012 20.5 5.1 0.0026 16.1 2.6 2.6 2 1 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family OAD_gamma PF04277.13 KXS99593.1 - 0.00075 20.0 0.0 0.0051 17.4 0.0 2.5 1 0 0 1 1 1 1 Oxaloacetate decarboxylase, gamma chain OSTbeta PF15048.6 KXS99593.1 - 0.0015 18.7 0.0 0.003 17.7 0.0 1.5 1 0 0 1 1 1 1 Organic solute transporter subunit beta protein DUF4381 PF14316.6 KXS99593.1 - 0.038 14.2 0.1 0.038 14.2 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF2615 PF11027.8 KXS99593.1 - 0.21 11.7 0.2 1.4 9.1 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2615) Vpu PF00558.19 KXS99593.1 - 1.4 8.7 3.8 0.34 10.7 0.3 1.8 2 0 0 2 2 2 0 Vpu protein UL42 PF17638.2 KXS99593.1 - 3.6 7.6 5.0 2.3 8.2 0.3 2.5 2 0 0 2 2 2 0 HCMV UL42 Glyco_hydro_43 PF04616.14 KXS99594.1 - 9.9e-13 48.0 6.4 2.5e-11 43.4 6.5 2.4 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 YacG PF03884.14 KXS99594.1 - 0.012 15.3 1.0 0.035 13.8 1.0 1.7 1 0 0 1 1 1 0 DNA gyrase inhibitor YacG DUF5326 PF17260.2 KXS99596.1 - 0.00061 19.9 0.3 0.0012 18.9 0.3 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5326) Methyltransf_28 PF02636.17 KXS99597.1 - 1.3e-41 143.0 0.0 1.9e-41 142.4 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.16 KXS99597.1 - 0.011 15.5 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase EspF PF04806.12 KXS99597.1 - 0.14 12.6 0.6 10 6.6 0.1 3.3 3 0 0 3 3 3 0 EspF protein repeat MRP-L47 PF06984.13 KXS99598.1 - 4.2e-22 78.1 0.5 6.6e-22 77.4 0.5 1.3 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) DUF4267 PF14087.6 KXS99607.1 - 1.2e-22 80.1 4.0 1.4e-22 79.9 4.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) Tom7 PF08038.12 KXS99607.1 - 0.13 11.9 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 TOM7 family PRIMA1 PF16101.5 KXS99609.1 - 0.033 14.2 2.8 0.043 13.9 2.4 1.3 1 1 0 1 1 1 0 Proline-rich membrane anchor 1 Synaptobrevin PF00957.21 KXS99609.1 - 0.065 13.0 2.0 0.12 12.2 2.0 1.4 1 0 0 1 1 1 0 Synaptobrevin DUF2207 PF09972.9 KXS99609.1 - 0.082 11.7 0.0 0.086 11.6 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) zf-CGNR PF11706.8 KXS99612.1 - 0.022 14.6 0.1 0.022 14.6 0.1 1.8 2 0 0 2 2 2 0 CGNR zinc finger FAM199X PF15814.5 KXS99613.1 - 0.19 10.8 4.3 0.21 10.6 4.3 1.1 1 0 0 1 1 1 0 Protein family FAM199X bZIP_C PF12498.8 KXS99613.1 - 0.19 12.7 5.8 0.23 12.5 5.5 1.4 1 1 0 1 1 1 0 Basic leucine-zipper C terminal Ndc1_Nup PF09531.10 KXS99613.1 - 2.6 6.6 10.2 2.6 6.6 10.2 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TFIIA PF03153.13 KXS99613.1 - 6.7 6.6 13.2 7.5 6.4 13.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Tyrosinase PF00264.20 KXS99614.1 - 3.8e-35 122.2 9.0 2.7e-34 119.4 9.0 2.0 1 1 0 1 1 1 1 Common central domain of tyrosinase CbtB PF09489.10 KXS99614.1 - 0.091 12.9 0.4 0.82 9.8 0.8 2.2 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) DUF3328 PF11807.8 KXS99615.1 - 3.2e-32 112.1 2.7 3.7e-32 111.9 2.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Flavodoxin_2 PF02525.17 KXS99616.1 - 0.062 13.0 0.1 0.21 11.3 0.0 2.0 2 0 0 2 2 2 0 Flavodoxin-like fold Fib_alpha PF08702.10 KXS99617.1 - 0.074 13.2 36.9 0.37 11.0 9.4 3.4 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Atg14 PF10186.9 KXS99617.1 - 0.15 11.1 51.3 0.048 12.7 28.9 2.9 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF812 PF05667.11 KXS99617.1 - 0.22 10.3 44.5 0.43 9.4 27.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Fez1 PF06818.15 KXS99617.1 - 0.38 11.2 48.1 2.8 8.3 23.6 3.3 1 1 2 3 3 3 0 Fez1 ATG16 PF08614.11 KXS99617.1 - 1.3 9.2 52.3 0.39 10.9 21.2 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF948 PF06103.11 KXS99617.1 - 2.1 8.6 18.5 3.8 7.8 1.7 4.0 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) SlyX PF04102.12 KXS99617.1 - 2.1 9.0 43.7 2.8 8.6 1.1 5.7 2 2 2 4 4 4 0 SlyX Spc7 PF08317.11 KXS99617.1 - 2.6 6.9 56.0 0.051 12.4 15.8 3.6 2 1 1 3 3 3 0 Spc7 kinetochore protein SAM_Exu PF18609.1 KXS99617.1 - 2.8 8.1 12.6 12 6.0 0.1 4.3 3 2 1 4 4 4 0 Exuperantia SAM-like domain Golgin_A5 PF09787.9 KXS99617.1 - 3.3 7.1 48.2 0.3 10.5 20.7 2.3 1 1 1 2 2 2 0 Golgin subfamily A member 5 AAA_15 PF13175.6 KXS99617.1 - 5.9 6.5 21.5 8.4 6.0 21.5 1.1 1 0 0 1 1 1 0 AAA ATPase domain DUF1819 PF08849.11 KXS99618.1 - 0.043 13.6 0.3 0.07 12.9 0.3 1.3 1 0 0 1 1 1 0 Putative inner membrane protein (DUF1819) HAP1_N PF04849.13 KXS99622.1 - 0.026 13.8 6.7 0.043 13.0 6.7 1.3 1 0 0 1 1 1 0 HAP1 N-terminal conserved region PTS_IIA PF02255.16 KXS99622.1 - 1.1 9.4 10.8 0.097 12.7 5.2 2.1 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit SYCE1 PF15233.6 KXS99622.1 - 2.2 8.3 12.8 5.2 7.1 12.8 1.5 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 CAP PF00188.26 KXS99624.1 - 0.12 13.2 6.5 2.1 9.2 2.1 2.9 3 0 0 3 3 3 0 Cysteine-rich secretory protein family DUF3328 PF11807.8 KXS99625.1 - 8.7e-36 123.8 1.1 1.1e-35 123.4 1.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Cellulase PF00150.18 KXS99626.1 - 2.6e-13 50.1 0.4 2.6e-13 50.1 0.4 1.9 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) TrmB PF01978.19 KXS99629.1 - 3.5e-05 23.6 1.7 37 4.3 0.0 5.0 5 0 0 5 5 5 0 Sugar-specific transcriptional regulator TrmB DUF4733 PF15878.5 KXS99629.1 - 0.00012 22.5 7.8 21 5.7 0.0 5.2 5 0 0 5 5 5 1 Domain of unknown function (DUF4733) CSD PF00313.22 KXS99629.1 - 0.00024 20.9 1.5 39 4.2 0.0 5.0 5 0 0 5 5 5 0 'Cold-shock' DNA-binding domain DUF2680 PF10925.8 KXS99629.1 - 0.0013 18.7 6.5 33 4.6 0.1 4.8 5 0 0 5 5 5 0 Protein of unknown function (DUF2680) MarR_2 PF12802.7 KXS99629.1 - 0.046 13.6 0.0 1.9e+02 2.0 0.0 4.4 5 0 0 5 5 5 0 MarR family Phage_CI_C PF16452.5 KXS99629.1 - 0.076 13.3 0.0 20 5.5 0.0 3.4 1 1 2 3 3 3 0 Bacteriophage CI repressor C-terminal domain Ycf34 PF10718.9 KXS99629.1 - 0.078 13.7 2.5 60 4.4 0.0 4.0 4 0 0 4 4 4 0 Hypothetical chloroplast protein Ycf34 RyR PF02026.16 KXS99629.1 - 0.31 11.3 5.7 20 5.5 0.2 3.3 1 1 4 5 5 5 0 RyR domain ABC2_membrane_5 PF13346.6 KXS99635.1 - 0.0011 18.6 4.0 0.0011 18.6 4.0 2.1 2 0 0 2 2 2 1 ABC-2 family transporter protein Mpv17_PMP22 PF04117.12 KXS99636.1 - 2.8e-19 69.1 1.0 5.4e-19 68.2 1.0 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF3341 PF11821.8 KXS99636.1 - 0.00058 19.5 0.3 0.00085 19.0 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3341) HgmA PF04209.13 KXS99637.1 - 1.6e-201 669.6 0.2 1.8e-201 669.4 0.2 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase KTI12 PF08433.10 KXS99638.1 - 1.4e-84 283.8 0.0 1.6e-84 283.6 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 KXS99638.1 - 0.015 15.4 0.0 0.028 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Acyl-CoA_dh_1 PF00441.24 KXS99639.1 - 6.6e-31 107.5 1.3 9.2e-31 107.1 1.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KXS99639.1 - 2.5e-23 82.1 0.1 5.3e-23 81.0 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KXS99639.1 - 3.7e-15 56.6 0.1 1.1e-14 55.0 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KXS99639.1 - 0.00018 21.8 0.2 0.00027 21.2 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain PAP2 PF01569.21 KXS99641.1 - 6e-26 90.8 0.5 6e-26 90.8 0.5 1.9 2 1 0 2 2 2 1 PAP2 superfamily DUF3325 PF11804.8 KXS99641.1 - 0.014 15.5 0.3 0.014 15.5 0.3 2.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3325) RseC_MucC PF04246.12 KXS99641.1 - 0.26 11.3 1.8 9.9 6.1 0.5 2.9 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC EptA_B_N PF08019.12 KXS99641.1 - 1.4 8.8 6.3 3.5 7.5 0.4 2.4 3 0 0 3 3 3 0 Phosphoethanolamine transferase EptA/EptB A_deaminase PF00962.22 KXS99645.1 - 2.2e-20 73.2 0.2 1.1e-19 71.0 0.0 1.9 2 0 0 2 2 2 1 Adenosine/AMP deaminase Med7 PF05983.11 KXS99646.1 - 3.7e-56 190.3 4.0 5.1e-56 189.8 4.0 1.2 1 0 0 1 1 1 1 MED7 protein API5 PF05918.11 KXS99646.1 - 0.022 13.6 1.1 0.036 12.9 1.1 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) SpecificRecomb PF10136.9 KXS99646.1 - 0.058 11.7 0.1 0.075 11.3 0.1 1.1 1 0 0 1 1 1 0 Site-specific recombinase FAA_hydrolase PF01557.18 KXS99647.1 - 1.3e-49 168.8 0.0 1.7e-49 168.5 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 KXS99647.1 - 6e-34 116.5 0.0 1.2e-33 115.5 0.0 1.5 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal p450 PF00067.22 KXS99648.1 - 1.8e-58 198.5 0.0 2e-58 198.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.32 KXS99649.1 - 8.5e-13 48.6 2.7 0.28 12.1 0.1 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS99649.1 - 0.0027 18.0 0.1 3.2 8.1 0.0 3.7 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Fungal_trans PF04082.18 KXS99650.1 - 7.5e-13 48.1 0.3 1.1e-12 47.6 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS99650.1 - 1.2e-09 38.1 9.0 3e-09 36.8 9.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXS99651.1 - 7.5e-13 48.1 0.3 1.1e-12 47.6 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS99651.1 - 1.2e-09 38.1 9.0 3e-09 36.8 9.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXS99652.1 - 1.4e-12 47.3 0.3 1.4e-12 47.3 0.3 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS99652.1 - 1.2e-09 38.1 9.0 3.5e-09 36.6 9.0 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXS99653.1 - 1.4e-12 47.3 0.3 1.4e-12 47.3 0.3 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS99653.1 - 1.2e-09 38.1 9.0 3.5e-09 36.6 9.0 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 KXS99654.1 - 1.4e-12 47.9 2.2 0.32 11.9 0.1 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS99654.1 - 0.0047 17.2 0.1 4.3 7.7 0.0 3.6 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXS99655.1 - 8.5e-13 48.6 2.7 0.28 12.1 0.1 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS99655.1 - 0.0027 18.0 0.1 3.2 8.1 0.0 3.7 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain OPT PF03169.15 KXS99658.1 - 0.0017 17.1 2.7 0.002 16.9 2.7 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Shisa PF13908.6 KXS99659.1 - 0.00079 19.7 1.1 0.00079 19.7 1.1 1.9 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator Trypan_PARP PF05887.11 KXS99659.1 - 0.0015 18.5 12.7 0.0015 18.5 12.7 1.5 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) DUF3180 PF11377.8 KXS99659.1 - 0.017 15.3 0.1 0.023 14.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3180) DUF4381 PF14316.6 KXS99659.1 - 0.07 13.4 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) ASC PF00858.24 KXS99659.1 - 0.078 11.9 0.0 0.078 11.9 0.0 1.2 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel COX2_TM PF02790.15 KXS99659.1 - 0.081 13.1 0.3 0.62 10.3 0.3 2.1 1 1 1 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain Neisseria_TspB PF05616.13 KXS99659.1 - 0.081 11.4 1.1 0.083 11.4 1.1 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein SPESP1 PF15754.5 KXS99659.1 - 0.27 10.3 5.5 0.34 10.1 5.5 1.3 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 FAP PF07174.11 KXS99659.1 - 0.72 9.3 9.8 1.1 8.7 9.8 1.3 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) TMEM154 PF15102.6 KXS99659.1 - 0.99 9.3 0.0 0.99 9.3 0.0 2.7 2 1 1 3 3 3 0 TMEM154 protein family PROL5-SMR PF15621.6 KXS99659.1 - 4.7 7.8 10.5 2.2 8.9 7.9 1.7 1 1 1 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family DUF3306 PF11748.8 KXS99659.1 - 6.3 7.7 9.0 15 6.5 9.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3306) Zds_C PF08632.10 KXS99660.1 - 9.9e-29 98.9 1.2 1.9e-28 98.0 1.2 1.5 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Prefoldin_2 PF01920.20 KXS99661.1 - 1.3e-18 66.8 7.7 2.4e-18 66.0 7.7 1.4 1 1 0 1 1 1 1 Prefoldin subunit T6PP_N PF18572.1 KXS99661.1 - 0.0037 17.1 2.4 0.0053 16.6 2.4 1.3 1 1 0 1 1 1 1 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain DUF5446 PF17522.2 KXS99661.1 - 0.021 15.0 4.0 0.072 13.3 0.4 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5446) EMP24_GP25L PF01105.24 KXS99661.1 - 0.023 14.6 4.2 0.12 12.3 0.1 2.1 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF1512 PF07431.12 KXS99661.1 - 0.024 13.6 0.1 0.051 12.6 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1512) Dynamitin PF04912.14 KXS99661.1 - 0.026 13.9 4.3 0.036 13.4 4.3 1.1 1 0 0 1 1 1 0 Dynamitin DUF4349 PF14257.6 KXS99661.1 - 0.04 13.4 4.0 0.095 12.1 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4349) DUF4200 PF13863.6 KXS99661.1 - 0.097 13.1 10.0 1.1 9.6 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) HR1 PF02185.16 KXS99661.1 - 0.098 12.8 10.6 0.11 12.6 1.8 2.3 1 1 1 2 2 2 0 Hr1 repeat Val_tRNA-synt_C PF10458.9 KXS99661.1 - 0.12 12.7 0.8 0.12 12.7 0.8 2.6 2 1 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Spc24 PF08286.11 KXS99661.1 - 0.36 11.1 7.6 0.59 10.4 2.0 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 RasGAP_C PF03836.15 KXS99661.1 - 0.46 10.6 7.4 2.1 8.5 1.3 2.2 2 1 0 2 2 2 0 RasGAP C-terminus FlaC_arch PF05377.11 KXS99661.1 - 0.64 10.5 4.2 0.94 9.9 0.2 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF4140 PF13600.6 KXS99661.1 - 0.64 10.5 5.7 1.4 9.4 0.2 2.2 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) YabA PF06156.13 KXS99661.1 - 0.84 10.3 6.9 11 6.8 6.9 2.0 1 1 0 1 1 1 0 Initiation control protein YabA DUF724 PF05266.14 KXS99661.1 - 1.1 9.1 7.5 1.8 8.3 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF812 PF05667.11 KXS99661.1 - 2 7.2 9.8 5.1 5.8 9.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF812) HAUS-augmin3 PF14932.6 KXS99661.1 - 3.3 7.2 12.0 2.2 7.8 3.5 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 SlyX PF04102.12 KXS99661.1 - 3.9 8.2 9.1 3.4 8.4 0.6 2.3 2 0 0 2 2 2 0 SlyX ABC_tran_CTD PF16326.5 KXS99661.1 - 7.4 6.9 13.0 0.35 11.1 1.0 2.7 2 1 0 2 2 2 0 ABC transporter C-terminal domain Fungal_trans PF04082.18 KXS99662.1 - 1e-27 96.8 0.0 1.9e-27 96.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS99662.1 - 7e-10 38.9 13.9 1.2e-09 38.2 13.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXS99663.1 - 8.7e-28 97.1 0.0 1.6e-27 96.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS99663.1 - 6.3e-10 39.0 13.9 1e-09 38.3 13.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_16 PF00722.21 KXS99664.1 - 5.8e-15 55.2 0.7 9.4e-15 54.5 0.7 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Abhydrolase_6 PF12697.7 KXS99665.1 - 1.1e-11 45.8 0.0 1.5e-11 45.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 KXS99665.1 - 0.001 18.8 0.3 0.0015 18.3 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.12 KXS99665.1 - 0.0085 15.7 0.2 0.26 10.9 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase Chlorophyllase2 PF12740.7 KXS99665.1 - 0.0088 15.0 0.2 0.014 14.3 0.2 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KXS99665.1 - 0.015 14.6 0.4 0.081 12.2 0.3 2.2 2 1 0 2 2 2 0 Serine aminopeptidase, S33 DUF676 PF05057.14 KXS99665.1 - 0.032 13.7 0.3 0.068 12.7 0.3 1.5 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 KXS99665.1 - 0.056 13.1 0.0 1.3 8.6 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold Mrr_cat PF04471.12 KXS99665.1 - 0.057 13.5 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease Chlorophyllase PF07224.11 KXS99665.1 - 0.11 11.5 0.1 0.16 11.0 0.1 1.4 1 1 0 1 1 1 0 Chlorophyllase UPF0180 PF03698.13 KXS99665.1 - 0.13 12.5 0.0 0.3 11.3 0.0 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0180) Saf-Nte_pilin PF09460.10 KXS99665.1 - 0.14 12.2 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Saf-pilin pilus formation protein Ceramidase PF05875.12 KXS99666.1 - 1.6e-105 352.3 9.3 1.9e-105 352.1 9.3 1.0 1 0 0 1 1 1 1 Ceramidase Gpi1 PF05024.15 KXS99666.1 - 0.062 13.4 1.7 0.099 12.7 0.3 1.9 1 1 1 2 2 2 0 N-acetylglucosaminyl transferase component (Gpi1) Mycobact_memb PF05423.13 KXS99666.1 - 0.21 11.5 0.3 0.38 10.7 0.3 1.5 1 0 0 1 1 1 0 Mycobacterium membrane protein Abhydrolase_1 PF00561.20 KXS99667.1 - 2e-15 57.1 0.0 8.3e-12 45.3 0.1 2.5 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXS99667.1 - 1.8e-10 41.8 0.0 4.2e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXS99667.1 - 8e-10 38.4 0.0 2e-09 37.1 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 EthD PF07110.11 KXS99667.1 - 0.0039 18.3 0.0 3.7 8.7 0.0 3.2 3 0 0 3 3 3 1 EthD domain Esterase PF00756.20 KXS99667.1 - 0.0077 15.9 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Putative esterase MS_channel PF00924.18 KXS99668.1 - 2.7e-24 85.9 1.8 4.2e-24 85.2 1.8 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_5 PF13202.6 KXS99668.1 - 0.00042 19.7 0.0 0.001 18.5 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXS99668.1 - 0.00078 19.2 0.0 0.0019 18.0 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 KXS99668.1 - 0.0019 17.6 0.2 0.0043 16.5 0.2 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KXS99668.1 - 0.029 14.8 0.1 0.09 13.2 0.1 1.8 1 0 0 1 1 1 0 EF-hand domain pair HhH-GPD PF00730.25 KXS99669.1 - 2.7e-06 27.8 0.0 5e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KXS99669.1 - 0.037 13.9 0.3 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix motif Peptidase_M41 PF01434.18 KXS99670.1 - 7.6e-66 221.6 0.0 1.6e-65 220.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KXS99670.1 - 4.5e-42 143.6 0.0 1.1e-41 142.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXS99670.1 - 8.9e-12 44.6 0.1 3.1e-11 42.9 0.1 2.0 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 KXS99670.1 - 4.5e-07 30.2 0.1 1.3e-06 28.7 0.1 1.8 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.14 KXS99670.1 - 0.00014 21.9 0.2 0.00099 19.1 0.0 2.5 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXS99670.1 - 0.0023 18.4 0.5 0.23 11.8 0.2 3.2 2 1 0 3 3 3 1 AAA ATPase domain TIP49 PF06068.13 KXS99670.1 - 0.0097 15.1 0.1 0.019 14.2 0.1 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 KXS99670.1 - 0.011 16.0 0.4 1.2 9.4 0.1 3.0 3 0 0 3 3 3 0 AAA domain RuvB_N PF05496.12 KXS99670.1 - 0.014 15.1 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain DUF5623 PF18536.1 KXS99670.1 - 0.068 13.5 0.1 0.17 12.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5623) AAA_2 PF07724.14 KXS99670.1 - 0.091 12.9 0.0 0.25 11.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 KXS99670.1 - 0.12 12.1 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Pkinase PF00069.25 KXS99671.1 - 5.4e-56 189.9 0.2 1.6e-34 119.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXS99671.1 - 1.1e-37 129.7 0.0 6.5e-25 87.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KXS99671.1 - 2.4e-05 23.8 1.4 0.00011 21.7 0.0 2.4 2 1 0 2 2 2 1 Kinase-like Cep57_CLD_2 PF14197.6 KXS99671.1 - 0.00042 20.3 4.3 0.00042 20.3 4.3 2.3 3 0 0 3 3 3 1 Centrosome localisation domain of PPC89 APH PF01636.23 KXS99671.1 - 0.0018 18.2 10.0 0.013 15.4 0.0 3.2 2 2 1 4 4 4 1 Phosphotransferase enzyme family BRE1 PF08647.11 KXS99671.1 - 0.024 14.7 7.2 0.065 13.3 3.6 2.5 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Phage_GP20 PF06810.11 KXS99671.1 - 0.063 13.1 6.5 0.31 10.8 7.1 1.8 2 0 0 2 2 2 0 Phage minor structural protein GP20 CP12 PF02672.15 KXS99671.1 - 0.078 13.7 3.3 0.37 11.6 3.3 2.2 1 0 0 1 1 1 0 CP12 domain DUF2458 PF10454.9 KXS99671.1 - 0.098 12.3 5.7 0.21 11.2 5.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) Pkinase_fungal PF17667.1 KXS99671.1 - 0.13 11.0 2.8 1 8.1 0.0 2.3 2 0 0 2 2 2 0 Fungal protein kinase FapA PF03961.13 KXS99671.1 - 0.28 9.8 3.2 0.12 10.9 1.0 1.4 2 0 0 2 2 2 0 Flagellar Assembly Protein A DNA_pol_delta_4 PF04081.13 KXS99671.1 - 0.39 11.1 3.8 0.91 9.9 3.8 1.6 1 0 0 1 1 1 0 DNA polymerase delta, subunit 4 APG6_N PF17675.1 KXS99671.1 - 3.5 8.2 16.4 1.3 9.5 10.1 2.9 3 0 0 3 3 3 0 Apg6 coiled-coil region DivIC PF04977.15 KXS99671.1 - 4.8 7.0 8.3 0.54 10.1 2.3 2.5 2 0 0 2 2 2 0 Septum formation initiator Spc7 PF08317.11 KXS99672.1 - 0.0041 16.1 5.0 0.0064 15.4 5.0 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein IPK PF03770.16 KXS99672.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Inositol polyphosphate kinase BLOC1_2 PF10046.9 KXS99672.1 - 0.54 10.6 2.4 5.4 7.4 0.2 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cytochrom_C PF00034.21 KXS99672.1 - 1.3 10.2 4.7 1.9 9.7 2.4 2.6 2 0 0 2 2 2 0 Cytochrome c DHR10 PF18595.1 KXS99672.1 - 6.4 6.9 15.4 0.13 12.4 3.3 2.9 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain DnaB_bind PF10410.9 KXS99680.1 - 0.3 11.3 0.9 0.71 10.1 0.9 1.6 1 0 0 1 1 1 0 DnaB-helicase binding domain of primase Fungal_trans PF04082.18 KXS99683.1 - 2.3e-24 85.8 0.1 4.6e-24 84.9 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS99683.1 - 0.0012 18.9 15.2 0.0019 18.3 15.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Syntaxin PF00804.25 KXS99684.1 - 1.8e-19 70.2 8.4 2.9e-19 69.5 8.4 1.2 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 KXS99684.1 - 1.4e-09 37.7 0.2 3.5e-09 36.5 0.2 1.7 1 0 0 1 1 1 1 SNARE domain Mod_r PF07200.13 KXS99684.1 - 0.033 14.3 13.1 0.94 9.6 6.3 2.2 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Synaptobrevin PF00957.21 KXS99684.1 - 0.071 12.9 3.0 0.2 11.5 3.0 1.7 1 1 0 1 1 1 0 Synaptobrevin Vac_Fusion PF02346.16 KXS99684.1 - 0.087 12.5 0.1 0.4 10.4 0.1 2.1 1 0 0 1 1 1 0 Chordopoxvirus multifunctional envelope protein A27 DUF2721 PF11026.8 KXS99684.1 - 0.19 11.6 0.8 0.62 9.9 0.0 2.2 3 1 0 3 3 3 0 Protein of unknown function (DUF2721) DUF3584 PF12128.8 KXS99684.1 - 0.28 8.7 19.4 0.51 7.8 4.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) SurA_N_3 PF13624.6 KXS99684.1 - 0.51 10.1 7.5 0.11 12.3 2.3 2.2 2 0 0 2 2 2 0 SurA N-terminal domain Allexi_40kDa PF05549.11 KXS99684.1 - 0.96 8.9 7.2 0.31 10.5 1.6 2.0 2 0 0 2 2 2 0 Allexivirus 40kDa protein DUF4094 PF13334.6 KXS99684.1 - 5.6 7.5 6.2 0.72 10.3 0.2 2.7 2 1 0 3 3 3 0 Domain of unknown function (DUF4094) Ligase_CoA PF00549.19 KXS99686.1 - 5.8e-34 117.1 2.3 5.9e-17 61.9 0.3 2.5 2 0 0 2 2 2 2 CoA-ligase CoA_binding PF02629.19 KXS99686.1 - 6.2e-15 55.7 0.5 2.6e-14 53.7 0.1 2.3 2 0 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.6 KXS99686.1 - 1e-08 35.0 0.1 1.3e-06 28.3 0.0 2.7 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_2 PF08442.10 KXS99686.1 - 0.035 13.7 0.0 0.13 11.8 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp domain Pox_A11 PF05061.13 KXS99686.1 - 0.15 11.3 0.1 0.23 10.7 0.1 1.2 1 0 0 1 1 1 0 Poxvirus A11 Protein CLTH PF10607.9 KXS99689.1 - 6.1e-27 94.3 1.6 1.5e-26 93.1 0.0 2.1 2 1 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KXS99689.1 - 0.013 15.4 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 LisH U-box PF04564.15 KXS99689.1 - 0.018 15.2 0.0 0.072 13.3 0.0 2.0 1 0 0 1 1 1 0 U-box domain zf-C2H2_9 PF16293.5 KXS99689.1 - 0.18 11.7 1.3 4.2 7.3 0.0 2.9 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) FapA PF03961.13 KXS99689.1 - 2.8 6.4 6.0 4.4 5.8 6.0 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A CFEM PF05730.11 KXS99691.1 - 3e-14 52.8 8.1 7.3e-14 51.6 8.1 1.7 1 0 0 1 1 1 1 CFEM domain TnsD PF15978.5 KXS99691.1 - 0.087 11.8 0.3 0.12 11.3 0.3 1.1 1 0 0 1 1 1 0 Tn7-like transposition protein D RIFIN PF02009.16 KXS99691.1 - 1.2 9.0 10.1 1.6 8.6 10.1 1.1 1 0 0 1 1 1 0 Rifin Cation_ATPase_C PF00689.21 KXS99692.1 - 8.1e-48 162.5 8.6 8.1e-48 162.5 8.6 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KXS99692.1 - 1e-37 129.5 1.1 1e-37 129.5 1.1 3.2 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 KXS99692.1 - 3.6e-23 81.4 0.0 9e-23 80.2 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KXS99692.1 - 9.6e-17 62.0 0.3 8e-16 59.0 0.3 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KXS99692.1 - 1.7e-05 24.7 1.4 2.7e-05 24.0 0.5 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXS99692.1 - 0.00012 21.7 0.2 0.00045 19.8 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus RskA PF10099.9 KXS99692.1 - 0.097 13.0 4.5 0.28 11.4 0.6 3.1 2 1 0 2 2 2 0 Anti-sigma-K factor rskA DUF2207 PF09972.9 KXS99692.1 - 0.23 10.2 0.8 10 4.8 0.0 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Fungal_trans PF04082.18 KXS99693.1 - 9.1e-17 61.0 0.2 2.3e-16 59.6 0.2 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXS99693.1 - 5.5e-08 32.8 10.2 1e-07 31.9 10.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.6 KXS99696.1 - 2.9e-08 33.6 0.0 4.9e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS99696.1 - 8.3e-05 22.1 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase CRF-BP PF05428.11 KXS99697.1 - 0.039 12.8 0.0 0.064 12.0 0.0 1.2 1 0 0 1 1 1 0 Corticotropin-releasing factor binding protein (CRF-BP) CRF-BP PF05428.11 KXS99698.1 - 0.039 12.8 0.0 0.064 12.0 0.0 1.2 1 0 0 1 1 1 0 Corticotropin-releasing factor binding protein (CRF-BP) CRF-BP PF05428.11 KXS99699.1 - 0.039 12.8 0.0 0.064 12.0 0.0 1.2 1 0 0 1 1 1 0 Corticotropin-releasing factor binding protein (CRF-BP) MFS_1 PF07690.16 KXS99700.1 - 3.9e-40 137.9 47.1 3.9e-40 137.9 47.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS99700.1 - 4.9e-12 45.4 10.3 4.9e-12 45.4 10.3 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 KXS99700.1 - 6.1e-05 22.0 8.9 6.1e-05 22.0 8.9 2.4 2 0 0 2 2 2 1 MFS_1 like family DUF4191 PF13829.6 KXS99700.1 - 0.001 18.4 0.0 0.001 18.4 0.0 2.9 4 0 0 4 4 4 1 Domain of unknown function (DUF4191) OATP PF03137.20 KXS99700.1 - 0.0044 15.4 2.0 0.0044 15.4 2.0 2.4 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Tudor_3 PF18115.1 KXS99701.1 - 9.7e-05 22.1 0.2 0.00018 21.3 0.2 1.4 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain DUF1325 PF07039.11 KXS99701.1 - 0.00029 20.9 0.8 0.00052 20.1 0.8 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain DUF4537 PF15057.6 KXS99701.1 - 0.012 15.7 0.1 0.018 15.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) SAWADEE PF16719.5 KXS99701.1 - 0.032 14.3 0.0 0.057 13.4 0.0 1.3 1 0 0 1 1 1 0 SAWADEE domain Tudor-knot PF11717.8 KXS99701.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Mito_fiss_reg PF05308.11 KXS99701.1 - 0.6 10.2 14.3 2.6 8.0 1.7 2.4 2 0 0 2 2 2 0 Mitochondrial fission regulator DUF4468 PF14730.6 KXS99702.1 - 0.15 12.4 0.1 1.4 9.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4468) with TBP-like fold NAD_binding_8 PF13450.6 KXS99703.1 - 3.5e-11 43.1 0.0 6.8e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KXS99703.1 - 0.00016 21.1 0.0 0.00054 19.4 0.0 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 KXS99703.1 - 0.00018 21.0 0.0 0.00035 20.0 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KXS99703.1 - 0.0016 17.2 0.0 0.0024 16.7 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 KXS99703.1 - 0.0037 16.4 0.1 0.0054 15.9 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KXS99703.1 - 0.0039 16.5 0.1 0.0061 15.8 0.1 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KXS99703.1 - 0.04 13.2 0.0 0.11 11.7 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXS99703.1 - 0.12 12.9 0.2 0.42 11.2 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXS99703.1 - 0.15 11.6 0.1 0.24 10.9 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF3328 PF11807.8 KXS99704.1 - 0.0039 17.0 0.0 0.0056 16.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 KXS99705.1 - 0.0033 17.2 0.0 0.0043 16.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) COX15-CtaA PF02628.15 KXS99706.1 - 9.8e-112 373.2 9.0 1.2e-111 372.9 9.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein NADH-u_ox-rdase PF10785.9 KXS99706.1 - 0.084 13.6 3.0 19 6.0 0.1 3.3 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit PAP1 PF08601.10 KXS99707.1 - 9.4e-56 190.1 47.4 5.2e-55 187.7 38.7 3.8 1 1 1 2 2 2 1 Transcription factor PAP1 bZIP_1 PF00170.21 KXS99707.1 - 1.8e-08 34.3 10.1 3.6e-08 33.4 10.1 1.5 1 0 0 1 1 1 1 bZIP transcription factor SHE3 PF17078.5 KXS99707.1 - 0.051 13.3 4.6 0.1 12.3 4.6 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 bZIP_Maf PF03131.17 KXS99707.1 - 0.25 11.9 9.3 0.52 10.9 9.3 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_2 PF07716.15 KXS99707.1 - 0.31 11.2 11.6 1.3 9.2 11.6 2.0 1 1 0 1 1 1 0 Basic region leucine zipper CENP-H PF05837.12 KXS99707.1 - 1.6 9.1 5.5 11 6.5 4.2 2.4 2 0 0 2 2 2 0 Centromere protein H (CENP-H) PAP1 PF08601.10 KXS99708.1 - 9.4e-56 190.1 47.4 5.2e-55 187.7 38.7 3.8 1 1 1 2 2 2 1 Transcription factor PAP1 bZIP_1 PF00170.21 KXS99708.1 - 1.8e-08 34.3 10.1 3.6e-08 33.4 10.1 1.5 1 0 0 1 1 1 1 bZIP transcription factor SHE3 PF17078.5 KXS99708.1 - 0.051 13.3 4.6 0.1 12.3 4.6 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 bZIP_Maf PF03131.17 KXS99708.1 - 0.25 11.9 9.3 0.52 10.9 9.3 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_2 PF07716.15 KXS99708.1 - 0.31 11.2 11.6 1.3 9.2 11.6 2.0 1 1 0 1 1 1 0 Basic region leucine zipper CENP-H PF05837.12 KXS99708.1 - 1.6 9.1 5.5 11 6.5 4.2 2.4 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Ferric_reduct PF01794.19 KXS99709.1 - 3.8e-15 56.1 11.9 3.8e-15 56.1 11.9 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component BTB PF00651.31 KXS99711.1 - 1.1e-24 86.8 0.4 1.5e-13 50.9 0.1 2.8 3 0 0 3 3 3 2 BTB/POZ domain Ank_4 PF13637.6 KXS99711.1 - 3.7e-08 33.7 0.1 9.9e-08 32.4 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXS99711.1 - 6.8e-06 26.6 0.1 2.7e-05 24.7 0.1 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXS99711.1 - 8.5e-06 25.9 0.0 2.3e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS99711.1 - 0.00043 20.5 0.3 0.087 13.4 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 KXS99711.1 - 0.00068 20.0 0.5 0.0082 16.6 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat YqzH PF14164.6 KXS99711.1 - 0.075 13.1 0.1 12 6.1 0.2 2.9 2 0 0 2 2 2 0 YqzH-like protein AMP-binding PF00501.28 KXS99712.1 - 9e-58 195.8 0.0 1.3e-57 195.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXS99712.1 - 7.3e-06 26.9 0.0 1.9e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Mito_carr PF00153.27 KXS99714.1 - 2.7e-65 216.3 0.5 3.2e-22 78.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Antimicrobial_8 PF08103.11 KXS99714.1 - 0.023 14.8 0.8 12 6.3 0.0 3.0 3 0 0 3 3 3 0 Uperin family Dicty_CTDC PF00526.18 KXS99715.1 - 0.012 15.4 0.5 0.012 15.4 0.5 2.5 3 0 0 3 3 3 0 Dictyostelium (slime mold) repeat Pmp3 PF01679.17 KXS99716.1 - 1.7e-23 82.5 9.3 2e-23 82.3 9.3 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Glyco_trans_2_3 PF13632.6 KXS99723.1 - 4.4e-18 65.9 4.3 4.4e-18 65.9 4.3 1.8 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KXS99723.1 - 1.7e-14 54.3 0.0 2.4e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KXS99723.1 - 1.5e-07 31.0 0.0 2.4e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KXS99723.1 - 0.00013 21.9 0.0 0.00019 21.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Vert_HS_TF PF06546.11 KXS99724.1 - 6 6.5 10.0 0.054 13.1 1.6 1.8 2 0 0 2 2 2 0 Vertebrate heat shock transcription factor SH3_6 PF12913.7 KXS99725.1 - 0.085 12.4 0.5 1.1 8.8 0.0 2.3 2 0 0 2 2 2 0 SH3 domain (SH3b1 type) MoCF_biosynth PF00994.24 KXS99726.1 - 8.5e-54 181.1 0.5 1.4e-28 99.3 0.0 2.4 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 KXS99726.1 - 2.5e-38 131.3 2.8 4.1e-38 130.6 2.8 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 KXS99726.1 - 7.4e-17 61.3 0.0 1.6e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) SelP_N PF04592.14 KXS99726.1 - 0.26 10.7 8.6 0.39 10.1 8.6 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region TetR_C_22 PF17928.1 KXS99727.1 - 0.11 12.8 0.0 0.3 11.4 0.0 1.8 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Metallophos PF00149.28 KXS99728.1 - 6.9e-32 111.6 0.0 1.9e-22 80.8 0.0 2.2 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KXS99728.1 - 0.18 12.3 0.1 0.54 10.7 0.1 1.8 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain PAC4 PF16093.5 KXS99729.1 - 0.15 12.3 0.1 0.47 10.7 0.1 1.8 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 MFS_1 PF07690.16 KXS99731.1 - 3.6e-32 111.7 31.0 4.8e-32 111.3 31.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KXS99731.1 - 1.7e-06 27.6 22.8 6.1e-06 25.8 8.4 2.1 1 1 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB DUF1180 PF06679.12 KXS99731.1 - 0.11 13.0 0.0 0.31 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) AA_permease PF00324.21 KXS99732.1 - 4.1e-117 391.7 37.5 5.1e-117 391.4 37.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXS99732.1 - 4.8e-33 114.6 37.3 6.1e-33 114.3 37.3 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1612 PF07756.12 KXS99732.1 - 0.049 13.9 0.4 1.9 8.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1612) Methyltransf_25 PF13649.6 KXS99733.1 - 1.4e-09 38.5 0.0 2.5e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXS99733.1 - 5.6e-09 35.7 0.0 8.6e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KXS99733.1 - 3.4e-07 30.9 0.0 6e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXS99733.1 - 1.6e-06 28.1 0.0 2.3e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXS99733.1 - 8.4e-05 23.1 0.0 0.00016 22.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXS99733.1 - 0.00013 21.8 0.0 0.0002 21.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Rsm22 PF09243.10 KXS99733.1 - 0.049 12.9 0.0 0.14 11.4 0.0 1.5 1 1 1 2 2 2 0 Mitochondrial small ribosomal subunit Rsm22 DUF43 PF01861.16 KXS99733.1 - 0.089 12.0 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain FAD_binding_2 PF00890.24 KXS99735.1 - 8.5e-13 48.2 0.0 1.1e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Cpn10 PF00166.21 KXS99736.1 - 2.3e-30 104.5 0.0 2.6e-30 104.3 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit GDP_Man_Dehyd PF16363.5 KXS99737.1 - 2.4e-41 142.2 0.0 3.6e-41 141.7 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KXS99737.1 - 1.3e-34 119.7 0.0 1.7e-34 119.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXS99737.1 - 1.2e-07 31.0 0.0 1.5e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.18 KXS99737.1 - 0.21 11.5 0.0 0.36 10.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Cpn10 PF00166.21 KXS99738.1 - 2.3e-30 104.5 0.0 2.6e-30 104.3 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit RNA_pol PF00940.19 KXS99739.1 - 2.3e-184 613.1 0.0 3.1e-184 612.6 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 KXS99739.1 - 1.1e-91 307.7 6.7 1.1e-91 307.7 6.7 2.2 2 0 0 2 2 2 1 DNA-directed RNA polymerase N-terminal RSN1_7TM PF02714.15 KXS99740.1 - 9.8e-89 297.3 22.3 9.8e-89 297.3 22.3 2.4 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KXS99740.1 - 5.1e-40 136.8 2.2 1.7e-39 135.1 0.7 2.8 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KXS99740.1 - 2.1e-38 132.3 0.2 3.2e-38 131.7 0.2 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KXS99740.1 - 1.6e-32 111.5 0.2 3.4e-32 110.5 0.2 1.6 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter RRM_1 PF00076.22 KXS99740.1 - 0.055 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3377 PF11857.8 KXS99740.1 - 0.092 12.7 4.8 3.4 7.7 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3377) FYVE PF01363.21 KXS99741.1 - 0.00038 20.5 39.8 0.039 14.1 10.2 3.4 1 1 2 3 3 3 3 FYVE zinc finger zf-C3HC4 PF00097.25 KXS99741.1 - 0.98 9.3 39.5 2.7 7.9 9.3 3.4 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) EHN PF06441.12 KXS99742.1 - 1.3e-35 122.0 2.2 5.6e-35 120.0 0.2 2.2 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KXS99742.1 - 1.6e-09 37.8 0.1 3.4e-09 36.7 0.1 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXS99742.1 - 0.0024 18.5 5.0 0.016 15.8 5.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family LRR_4 PF12799.7 KXS99744.1 - 5.8e-19 67.9 35.5 0.00049 20.4 2.7 8.3 5 2 2 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXS99744.1 - 4.6e-16 58.3 29.8 0.00066 19.4 1.3 6.4 4 2 2 6 6 6 5 Leucine rich repeat LRR_9 PF14580.6 KXS99744.1 - 1.3e-09 37.8 8.5 0.00018 21.0 0.1 3.5 2 1 1 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 KXS99744.1 - 0.19 12.4 28.2 7.2 7.6 0.5 9.4 8 2 0 8 8 8 0 Leucine Rich Repeat LRR_6 PF13516.6 KXS99744.1 - 0.55 10.4 25.3 1.8 8.8 0.4 8.0 9 0 0 9 9 9 0 Leucine Rich repeat DUF3510 PF12022.8 KXS99744.1 - 0.99 9.8 6.4 0.12 12.7 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3510) DUF998 PF06197.13 KXS99745.1 - 7.3e-06 25.7 3.2 7.3e-06 25.7 3.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF998) Frag1 PF10277.9 KXS99745.1 - 0.01 15.4 0.1 0.032 13.8 0.1 1.9 1 1 1 2 2 2 0 Frag1/DRAM/Sfk1 family SpoVAC_SpoVAEB PF03862.13 KXS99745.1 - 0.034 14.4 0.6 0.071 13.4 0.6 1.6 1 1 0 1 1 1 0 SpoVAC/SpoVAEB sporulation membrane protein MnhB PF04039.13 KXS99745.1 - 0.051 13.9 2.3 0.087 13.1 0.9 2.1 2 0 0 2 2 2 0 Domain related to MnhB subunit of Na+/H+ antiporter CBFD_NFYB_HMF PF00808.23 KXS99746.1 - 3.4e-09 36.9 0.2 8.2e-09 35.6 0.2 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAFII28 PF04719.14 KXS99746.1 - 0.0044 17.1 0.2 0.0091 16.1 0.2 1.5 1 0 0 1 1 1 1 hTAFII28-like protein conserved region Histone PF00125.24 KXS99746.1 - 0.091 13.1 0.3 0.091 13.1 0.3 1.5 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 NUC153 PF08159.12 KXS99747.1 - 6.3e-18 64.3 10.6 7.8e-15 54.4 1.1 3.8 3 0 0 3 3 3 3 NUC153 domain Glyco_hydro_16 PF00722.21 KXS99748.1 - 1.6e-07 31.0 1.1 9.2e-07 28.5 0.6 2.3 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 Acyl_transf_3 PF01757.22 KXS99748.1 - 1.7e-05 24.1 46.3 3.3e-05 23.1 46.3 1.5 1 0 0 1 1 1 1 Acyltransferase family DUF2418 PF10332.9 KXS99748.1 - 0.49 10.9 5.4 1.3 9.6 5.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2418) Thr_synth_N PF14821.6 KXS99749.1 - 1.3e-29 102.2 0.0 2.7e-29 101.2 0.0 1.6 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 KXS99749.1 - 4.9e-13 49.2 0.0 6.2e-12 45.5 0.0 2.1 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ESSS PF10183.9 KXS99750.1 - 1.5 9.1 6.3 22 5.3 0.1 3.7 4 0 0 4 4 4 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) zf-ZPR1 PF03367.13 KXS99751.1 - 1.2e-112 373.0 0.1 5.1e-56 188.9 0.0 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain PASTA PF03793.19 KXS99751.1 - 0.34 10.8 1.9 12 5.8 0.1 3.2 3 0 0 3 3 3 0 PASTA domain DnaJ_CXXCXGXG PF00684.19 KXS99751.1 - 0.74 10.2 4.7 2.4 8.6 0.2 2.5 2 0 0 2 2 2 0 DnaJ central domain zinc-ribbons_6 PF07191.12 KXS99751.1 - 1 9.4 3.9 3.6 7.6 0.5 2.4 2 0 0 2 2 2 0 zinc-ribbons Zn-ribbon_8 PF09723.10 KXS99751.1 - 1.2 9.3 7.1 21 5.3 0.1 4.2 4 0 0 4 4 4 0 Zinc ribbon domain GCP_N_terminal PF17681.1 KXS99752.1 - 3.8e-35 122.0 0.4 8.5e-35 120.8 0.0 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KXS99752.1 - 5.5e-23 81.9 2.5 9.5e-23 81.1 2.5 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal RNase_P_Rpp14 PF01900.19 KXS99753.1 - 5.7e-35 119.7 0.0 7.8e-35 119.2 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family PBP PF01161.20 KXS99754.1 - 2.7e-14 53.6 0.1 4.7e-14 52.8 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Fels1 PF05666.11 KXS99754.1 - 0.012 15.2 0.1 0.031 13.9 0.1 1.6 1 0 0 1 1 1 0 Fels-1 Prophage Protein-like Voltage_CLC PF00654.20 KXS99755.1 - 3.5e-87 293.0 26.8 3.5e-87 293.0 26.8 1.8 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KXS99755.1 - 1.1e-09 38.6 0.0 0.00025 21.4 0.0 2.5 2 0 0 2 2 2 2 CBS domain COesterase PF00135.28 KXS99756.1 - 7.2e-105 351.8 0.0 8.9e-105 351.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXS99756.1 - 5.7e-08 32.9 0.2 2.8e-07 30.6 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold ANAPC4_WD40 PF12894.7 KXS99758.1 - 7.5e-07 29.4 0.0 9.8e-05 22.6 0.0 3.3 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXS99758.1 - 0.00055 20.7 17.5 0.039 14.8 0.0 6.1 5 1 0 5 5 5 2 WD domain, G-beta repeat Lactonase PF10282.9 KXS99758.1 - 0.0018 17.6 0.0 0.0029 16.9 0.0 1.4 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Cytochrom_D1 PF02239.16 KXS99758.1 - 0.0018 16.9 0.0 0.0027 16.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain IKI3 PF04762.12 KXS99758.1 - 0.02 12.9 0.0 0.03 12.3 0.0 1.2 1 0 0 1 1 1 0 IKI3 family PD40 PF07676.12 KXS99758.1 - 0.1 12.6 0.2 14 5.8 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KXS99758.1 - 0.17 10.8 0.1 0.95 8.4 0.0 2.2 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein VID27 PF08553.10 KXS99758.1 - 0.18 10.8 0.0 0.28 10.2 0.0 1.4 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain CP12 PF02672.15 KXS99765.1 - 9.1 7.1 7.4 15 6.4 2.5 2.9 2 0 0 2 2 2 0 CP12 domain JmjC PF02373.22 KXS99769.1 - 3.5e-05 24.2 0.0 0.0037 17.7 0.0 2.5 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 KXS99769.1 - 0.2 11.3 1.0 0.56 9.9 0.3 2.1 2 1 0 2 2 2 0 Cupin-like domain Hep_59 PF07052.11 KXS99775.1 - 5 7.9 6.1 2.5 8.9 0.4 2.6 2 1 1 3 3 3 0 Hepatocellular carcinoma-associated antigen 59 Yqai PF09466.10 KXS99776.1 - 0.044 14.1 0.2 0.079 13.3 0.2 1.5 1 0 0 1 1 1 0 Hypothetical protein Yqai Cas_Csa4 PF09703.10 KXS99780.1 - 0.21 10.8 0.0 0.24 10.7 0.0 1.0 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa4) Trypan_PARP PF05887.11 KXS99781.1 - 7.3 6.6 17.2 0.26 11.3 10.4 1.8 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) Peptidase_C48 PF02902.19 KXS99784.1 - 8.7e-07 29.0 0.0 1.7e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Mac_assoc PF16628.5 KXS99785.1 - 0.33 11.2 2.8 0.19 11.9 0.5 1.7 1 1 1 2 2 2 0 Unstructured region on maltose acetyltransferase Cys_Met_Meta_PP PF01053.20 KXS99794.1 - 4.3e-132 440.2 0.0 5.4e-132 439.9 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme CoA_binding_2 PF13380.6 KXS99794.1 - 2.5e-39 134.3 0.6 1.3e-38 132.0 0.1 2.3 3 0 0 3 3 3 1 CoA binding domain Aminotran_5 PF00266.19 KXS99794.1 - 5.3e-07 28.9 0.0 1.1e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KXS99794.1 - 7e-07 28.9 0.0 1.1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family CoA_binding PF02629.19 KXS99794.1 - 1.9e-06 28.5 0.0 1.2e-05 25.9 0.0 2.2 2 0 0 2 2 2 1 CoA binding domain Beta_elim_lyase PF01212.21 KXS99794.1 - 5.9e-05 22.5 0.0 0.00021 20.7 0.0 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KXS99794.1 - 6.3e-05 22.3 0.0 0.0001 21.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II GDC-P PF02347.16 KXS99794.1 - 0.00031 19.7 0.0 0.00046 19.1 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein P5CR_dimer PF14748.6 KXS99795.1 - 2.7e-31 107.9 0.2 4.8e-31 107.1 0.2 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KXS99795.1 - 2.3e-09 37.7 2.0 1.8e-07 31.7 0.5 3.1 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent RE_Alw26IDE PF09665.10 KXS99795.1 - 0.045 12.9 0.0 0.064 12.4 0.0 1.1 1 0 0 1 1 1 0 Type II restriction endonuclease (RE_Alw26IDE) HECT PF00632.25 KXS99797.1 - 2.3e-80 270.3 0.0 4e-80 269.6 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) FAM176 PF14851.6 KXS99797.1 - 3.6 7.2 6.1 8.4 6.0 6.1 1.5 1 0 0 1 1 1 0 FAM176 family zf-MYND PF01753.18 KXS99799.1 - 1e-08 35.1 17.4 1.9e-08 34.3 17.4 1.5 1 0 0 1 1 1 1 MYND finger RNase_H2-Ydr279 PF09468.10 KXS99799.1 - 0.042 14.0 0.1 0.084 13.0 0.1 1.4 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) wHTH domain eIF-4B PF06273.11 KXS99799.1 - 0.073 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B WH2 PF02205.20 KXS99799.1 - 0.12 12.2 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 WH2 motif zf-Mss51 PF13824.6 KXS99799.1 - 0.81 9.8 8.2 2.4 8.3 8.2 1.8 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 HsbA PF12296.8 KXS99800.1 - 5.7e-06 26.8 3.5 6.8e-06 26.5 0.9 1.9 1 1 1 2 2 2 1 Hydrophobic surface binding protein A CHD5 PF04420.14 KXS99801.1 - 2.6e-58 196.4 2.9 3.3e-58 196.0 2.9 1.1 1 0 0 1 1 1 1 CHD5-like protein YnfE PF17452.2 KXS99801.1 - 0.0076 16.5 0.6 0.013 15.8 0.6 1.3 1 0 0 1 1 1 1 Uncharacterized YnfE-like DUF572 PF04502.13 KXS99801.1 - 0.028 14.0 3.8 0.041 13.5 3.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) ZapB PF06005.12 KXS99801.1 - 0.41 11.1 4.4 1.3 9.5 4.4 1.7 1 1 0 1 1 1 0 Cell division protein ZapB DivIC PF04977.15 KXS99801.1 - 7.5 6.4 8.8 4 7.3 5.1 2.4 2 1 1 3 3 3 0 Septum formation initiator MtrF PF09472.10 KXS99802.1 - 0.58 9.6 3.1 0.93 8.9 3.1 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) TPR_MLP1_2 PF07926.12 KXS99803.1 - 1.6e-36 125.2 26.3 1.6e-36 125.2 26.3 20.0 8 4 10 18 18 18 10 TPR/MLP1/MLP2-like protein MscS_porin PF12795.7 KXS99803.1 - 9.3e-06 25.4 61.9 1.3e-05 24.9 40.6 14.9 5 2 8 14 14 14 5 Mechanosensitive ion channel porin domain Fungal_TACC PF12709.7 KXS99803.1 - 0.0076 16.7 3.3 0.0076 16.7 3.3 20.5 15 7 11 26 26 26 1 Fungal Transforming acidic coiled-coil (TACC) proteins DUF3693 PF12472.8 KXS99803.1 - 0.066 12.9 1.0 0.24 11.1 1.0 2.0 1 0 0 1 1 1 0 Phage related protein Surfac_D-trimer PF09006.11 KXS99803.1 - 2.1 8.3 14.6 9.5 6.2 0.1 8.0 9 0 0 9 9 9 0 Lung surfactant protein D coiled-coil trimerisation NOC3p PF07540.11 KXS99805.1 - 1e-31 109.2 0.0 1e-31 109.2 0.0 2.6 4 0 0 4 4 4 1 Nucleolar complex-associated protein CBF PF03914.17 KXS99805.1 - 2.4e-25 89.5 1.7 4.1e-25 88.8 0.2 2.1 2 0 0 2 2 2 1 CBF/Mak21 family DUF3545 PF12065.8 KXS99805.1 - 0.15 12.1 5.2 0.47 10.5 5.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3545) p450 PF00067.22 KXS99806.1 - 2.3e-42 145.4 0.0 6.3e-42 143.9 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 CTP_transf_like PF01467.26 KXS99807.1 - 2.4e-17 63.5 0.0 1.1e-13 51.6 0.0 3.4 3 0 0 3 3 3 3 Cytidylyltransferase-like MFS_1 PF07690.16 KXS99808.1 - 2.8e-30 105.4 25.8 2.8e-30 105.4 25.8 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS99808.1 - 7.2e-13 48.2 3.5 7.2e-13 48.2 3.5 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 KXS99808.1 - 8.4e-06 24.5 3.6 1.3e-05 23.8 3.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) HhH-GPD PF00730.25 KXS99811.1 - 4.9e-13 49.5 0.0 8.4e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HET PF06985.11 KXS99812.1 - 6.2e-25 88.3 0.1 1.1e-24 87.4 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HTH_12 PF08461.10 KXS99812.1 - 0.19 11.7 0.1 0.43 10.5 0.1 1.5 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain Sec63 PF02889.16 KXS99813.1 - 2.7e-30 105.4 0.0 4.4e-30 104.7 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 KXS99813.1 - 5.3e-25 88.2 0.1 3.4e-24 85.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KXS99813.1 - 8.7e-12 45.4 0.0 2.2e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KXS99813.1 - 8.3e-08 32.6 0.0 3.2e-07 30.7 0.0 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 KXS99813.1 - 0.029 14.7 0.0 0.2 12.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KXS99813.1 - 0.085 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain HHH_5 PF14520.6 KXS99813.1 - 0.093 13.4 0.0 0.46 11.1 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix domain Nuc_sug_transp PF04142.15 KXS99814.1 - 3.6e-88 295.8 11.7 6.1e-88 295.0 11.7 1.4 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 KXS99814.1 - 5.5e-05 23.4 3.0 5.5e-05 23.4 3.0 2.8 2 1 0 2 2 2 1 EamA-like transporter family DUF5379 PF17350.2 KXS99814.1 - 0.0084 16.4 4.2 0.0084 16.4 4.2 2.7 3 0 0 3 3 3 1 Family of unknown function (DUF5379) DUF202 PF02656.15 KXS99814.1 - 0.32 11.5 0.1 0.32 11.5 0.1 3.6 3 3 1 4 4 4 0 Domain of unknown function (DUF202) Sec63 PF02889.16 KXS99815.1 - 2.7e-30 105.4 0.0 4.4e-30 104.7 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 KXS99815.1 - 5.3e-25 88.2 0.1 3.4e-24 85.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KXS99815.1 - 8.7e-12 45.4 0.0 2.2e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KXS99815.1 - 8.3e-08 32.6 0.0 3.2e-07 30.7 0.0 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 KXS99815.1 - 0.029 14.7 0.0 0.2 12.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KXS99815.1 - 0.085 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain HHH_5 PF14520.6 KXS99815.1 - 0.093 13.4 0.0 0.46 11.1 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix domain IKI3 PF04762.12 KXS99817.1 - 9.5e-291 967.1 0.0 1.1e-290 966.8 0.0 1.1 1 0 0 1 1 1 1 IKI3 family 7TMR-HDED PF07697.11 KXS99817.1 - 0.14 12.3 2.4 0.91 9.6 1.5 2.4 2 1 0 2 2 2 0 7TM-HD extracellular Clathrin PF00637.20 KXS99817.1 - 0.42 10.5 4.3 1.7 8.5 0.2 2.7 2 1 0 2 2 2 0 Region in Clathrin and VPS TPR_19 PF14559.6 KXS99817.1 - 5.1 7.7 5.5 3.4 8.2 2.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3544 PF12064.8 KXS99818.1 - 0.0091 16.3 0.2 0.01 16.1 0.2 1.1 1 0 0 1 1 1 1 Protein kinase C-binding protein 1 CCDC53 PF10152.9 KXS99818.1 - 0.12 12.8 1.6 0.12 12.7 1.6 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF390 PF04094.14 KXS99818.1 - 9.4 4.4 7.6 9.8 4.3 7.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF390) Ish1 PF10281.9 KXS99819.1 - 0.012 15.9 0.0 0.044 14.1 0.0 2.0 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein DnaJ PF00226.31 KXS99820.1 - 2.4e-10 40.4 0.0 5.6e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain RNA_pol_Rbc25 PF08292.12 KXS99820.1 - 0.039 14.2 0.3 0.071 13.3 0.3 1.4 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 Asp-B-Hydro_N PF05279.11 KXS99820.1 - 2.2 8.3 7.2 3.3 7.7 7.2 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region UCR_14kD PF02271.16 KXS99821.1 - 7.1e-45 151.1 0.2 8.3e-45 150.8 0.2 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit DUF1712 PF08217.11 KXS99822.1 - 4.2e-12 45.4 0.0 8.4e-11 41.1 0.0 2.6 2 1 0 2 2 2 1 Fungal domain of unknown function (DUF1712) UPF0113_N PF17833.1 KXS99823.1 - 2.9e-26 91.8 0.0 3.9e-26 91.4 0.0 1.2 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 KXS99823.1 - 4.9e-25 87.6 0.0 4.8e-24 84.4 0.0 2.1 2 0 0 2 2 2 1 UPF0113 PUA domain Sortase PF04203.13 KXS99823.1 - 0.065 13.0 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 Sortase domain Aminotran_1_2 PF00155.21 KXS99824.1 - 5.9e-38 131.0 0.0 7.2e-38 130.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II MFS_1 PF07690.16 KXS99825.1 - 1.6e-23 83.2 37.6 1.6e-23 83.2 37.6 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 KXS99825.1 - 1.1e-06 27.5 2.4 1.1e-06 27.5 2.4 2.4 2 1 0 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.7 KXS99825.1 - 0.34 9.7 13.4 0.18 10.6 2.1 3.0 1 1 3 4 4 4 0 MFS_1 like family SAP PF02037.27 KXS99828.1 - 0.042 13.6 0.3 3 7.7 0.2 2.9 3 0 0 3 3 3 0 SAP domain TMEM154 PF15102.6 KXS99829.1 - 0.0017 18.2 0.7 0.0034 17.3 0.0 1.8 2 0 0 2 2 2 1 TMEM154 protein family DUF3827 PF12877.7 KXS99829.1 - 0.013 13.9 0.0 0.036 12.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Syndecan PF01034.20 KXS99829.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain G-patch PF01585.23 KXS99830.1 - 7.2e-10 38.6 2.4 1.5e-09 37.6 2.4 1.5 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 KXS99830.1 - 0.00091 19.0 0.0 0.002 17.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mito_carr PF00153.27 KXS99831.1 - 5.6e-62 205.7 5.4 3.5e-23 81.3 0.2 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein TFA2_Winged_2 PF18121.1 KXS99832.1 - 2.6e-18 65.4 0.0 5.7e-18 64.4 0.0 1.6 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 KXS99832.1 - 4.3e-11 42.9 0.1 1.1e-10 41.7 0.1 1.7 1 0 0 1 1 1 1 TFIIE beta subunit core domain Peptidase_S10 PF00450.22 KXS99833.1 - 2.1e-76 258.0 0.6 4.4e-76 257.0 0.6 1.5 1 0 0 1 1 1 1 Serine carboxypeptidase Endotoxin_C2 PF18449.1 KXS99834.1 - 0.051 13.9 0.1 0.13 12.6 0.1 1.6 1 0 0 1 1 1 0 Delta endotoxin TPR_2 PF07719.17 KXS99839.1 - 9.6e-06 25.3 2.7 0.083 13.0 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KXS99839.1 - 0.0028 18.2 0.9 0.06 14.0 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXS99839.1 - 0.01 16.1 1.6 1.5 9.2 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXS99839.1 - 0.011 15.6 4.4 0.43 10.5 0.9 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 KXS99839.1 - 0.019 15.0 0.0 0.061 13.4 0.0 1.9 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain TPR_19 PF14559.6 KXS99839.1 - 0.023 15.2 1.4 2.2 8.8 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXS99839.1 - 0.031 14.5 1.2 2.8 8.4 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXS99839.1 - 0.26 11.2 1.1 33 4.5 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 KXS99839.1 - 0.54 10.0 5.1 0.37 10.5 0.8 2.5 2 0 0 2 2 2 0 TPR repeat TPR_16 PF13432.6 KXS99839.1 - 0.66 10.7 3.9 9.9 6.9 0.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Sugar_tr PF00083.24 KXS99840.1 - 2e-78 264.3 17.8 2.3e-78 264.1 17.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS99840.1 - 9.9e-17 60.9 26.4 9.9e-17 60.9 26.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KXS99840.1 - 1.8e-05 24.3 5.6 1.8e-05 24.3 5.6 2.6 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 KXS99840.1 - 0.073 11.9 13.0 0.017 14.0 6.2 2.5 3 0 0 3 3 3 0 MFS_1 like family DUF4804 PF16062.5 KXS99841.1 - 5.3e-80 269.4 0.0 7.9e-42 143.6 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4804) Nitroreductase PF00881.24 KXS99841.1 - 9.5e-14 51.8 0.0 1.8e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Nitroreductase family CDC45 PF02724.14 KXS99856.1 - 3.4 5.9 8.1 4.2 5.5 8.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Ank_2 PF12796.7 KXS99857.1 - 7.2e-71 234.8 7.8 8.2e-12 45.5 0.0 7.1 1 1 6 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXS99857.1 - 5.8e-60 198.9 19.4 1.1e-10 41.8 0.0 9.6 3 2 7 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXS99857.1 - 2.5e-52 168.7 6.5 0.0011 19.3 0.0 12.9 13 0 0 13 13 13 11 Ankyrin repeat Ank PF00023.30 KXS99857.1 - 1.9e-50 167.2 22.0 0.0006 20.1 0.0 12.9 13 1 1 14 14 14 11 Ankyrin repeat Ank_5 PF13857.6 KXS99857.1 - 4.1e-43 144.9 18.6 1.2e-06 28.7 0.2 9.6 4 3 4 9 9 9 8 Ankyrin repeats (many copies) MIT PF04212.18 KXS99858.1 - 9.2e-15 54.5 0.3 2.5e-14 53.1 0.3 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain zf-UBR PF02207.20 KXS99859.1 - 3.4e-14 52.7 6.4 3.4e-14 52.7 6.4 3.6 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) Mad3_BUB1_I PF08311.12 KXS99860.1 - 7.1e-46 155.2 0.2 1.7e-45 154.0 0.2 1.7 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 KXS99860.1 - 1.5e-10 40.9 0.8 1.3e-09 37.8 0.0 2.5 3 0 0 3 3 3 1 Protein kinase domain Mad3_BUB1_II PF08171.11 KXS99860.1 - 3e-08 33.7 2.0 9.4e-08 32.1 0.0 2.7 3 0 0 3 3 3 1 Mad3/BUB1 homology region 2 Mad3_BUB1_I_2 PF17014.5 KXS99860.1 - 0.0014 18.7 0.0 0.0091 16.1 0.0 2.2 2 0 0 2 2 2 1 Putative Mad3/BUB1 like region 1 protein Pkinase_Tyr PF07714.17 KXS99860.1 - 0.004 16.5 0.0 0.014 14.7 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXS99860.1 - 0.028 14.3 2.0 0.054 13.4 0.1 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family CPSase_L_D2 PF02786.17 KXS99861.1 - 9.1e-60 201.8 0.0 1.4e-59 201.1 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 KXS99861.1 - 4e-31 107.3 0.0 8.1e-31 106.3 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 KXS99861.1 - 9.3e-31 106.6 0.0 2.3e-30 105.4 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 KXS99861.1 - 2.9e-11 43.0 3.3 9.1e-11 41.4 3.3 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KXS99861.1 - 5.8e-10 39.0 0.0 1.1e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KXS99861.1 - 9.3e-07 28.6 0.0 5.7e-06 26.0 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KXS99861.1 - 0.00011 22.3 0.0 0.0002 21.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain DUF2118 PF09891.9 KXS99861.1 - 0.005 16.8 0.1 0.011 15.7 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2118) ATPgrasp_ST PF14397.6 KXS99861.1 - 0.01 15.1 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp ATPgrasp_YheCD PF14398.6 KXS99861.1 - 0.03 13.6 0.0 0.068 12.4 0.0 1.5 1 0 0 1 1 1 0 YheC/D like ATP-grasp DUF5017 PF16409.5 KXS99861.1 - 0.043 13.3 0.0 0.083 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5017) RimK PF08443.11 KXS99861.1 - 0.05 13.2 0.0 0.15 11.6 0.0 1.9 1 1 0 1 1 1 0 RimK-like ATP-grasp domain GSH-S_ATP PF02955.16 KXS99861.1 - 0.054 12.9 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain TMEM154 PF15102.6 KXS99862.1 - 0.92 9.4 4.2 0.44 10.4 0.9 1.9 2 0 0 2 2 2 0 TMEM154 protein family p450 PF00067.22 KXS99863.1 - 1.2e-45 156.1 0.0 2.7e-45 155.0 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 NTF2 PF02136.20 KXS99864.1 - 6.5e-07 29.9 0.0 7.5e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain OB_NTP_bind PF07717.16 KXS99865.1 - 1.6e-21 76.4 0.0 7.9e-21 74.2 0.0 2.2 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KXS99865.1 - 5.2e-19 68.5 0.0 5.2e-19 68.5 0.0 4.1 3 1 0 3 3 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KXS99865.1 - 5.4e-13 49.3 0.0 1.4e-12 47.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KXS99865.1 - 1.5e-05 25.2 0.0 5.6e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 KXS99865.1 - 3.4e-05 23.7 0.0 8.9e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 KXS99865.1 - 0.0009 18.4 0.0 0.0018 17.4 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 KXS99865.1 - 0.0063 16.3 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain PWI PF01480.17 KXS99865.1 - 0.0068 16.7 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 PWI domain ATPase PF06745.13 KXS99865.1 - 0.033 13.5 0.0 0.09 12.1 0.0 1.7 1 0 0 1 1 1 0 KaiC SRP54 PF00448.22 KXS99865.1 - 0.084 12.5 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ABC_tran PF00005.27 KXS99865.1 - 0.6 10.6 0.0 0.6 10.6 0.0 3.0 3 1 0 3 3 3 0 ABC transporter TTSSLRR PF12468.8 KXS99865.1 - 0.65 10.3 4.6 5.5 7.3 0.5 3.1 3 0 0 3 3 3 0 Type III secretion system leucine rich repeat protein Cyt-b5 PF00173.28 KXS99866.1 - 1.8e-17 63.3 0.1 2e-17 63.1 0.1 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain BRX PF08381.11 KXS99866.1 - 0.29 10.5 1.7 6.3 6.2 1.7 2.7 1 1 0 1 1 1 0 Transcription factor regulating root and shoot growth via Pin3 Sec8_exocyst PF04048.14 KXS99867.1 - 0.011 15.6 0.0 0.041 13.8 0.0 2.0 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain CK2S PF15011.6 KXS99867.1 - 0.012 15.5 0.1 0.032 14.1 0.1 1.7 1 0 0 1 1 1 0 Casein Kinase 2 substrate AbiH PF14253.6 KXS99867.1 - 0.033 14.1 0.1 0.054 13.4 0.1 1.4 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH ADP_ribosyl_GH PF03747.14 KXS99867.1 - 0.11 12.2 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase TT1725 PF18324.1 KXS99867.1 - 0.14 12.3 0.1 0.39 10.8 0.1 1.7 1 0 0 1 1 1 0 Hypothetical protein TT1725 Gly_transf_sug PF04488.15 KXS99869.1 - 1.6e-13 51.1 0.1 3.5e-13 50.0 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KXS99869.1 - 0.037 13.4 0.0 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein LapA_dom PF06305.11 KXS99869.1 - 2.8 7.8 4.4 2.2 8.1 1.0 2.4 1 1 1 2 2 2 0 Lipopolysaccharide assembly protein A domain zinc_ribbon_16 PF17034.5 KXS99870.1 - 0.11 12.7 0.3 0.31 11.3 0.3 1.7 1 0 0 1 1 1 0 Zinc-ribbon like family Coatomer_WDAD PF04053.14 KXS99871.1 - 2.4e-148 494.9 0.0 3.8e-148 494.2 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 KXS99871.1 - 1.4e-91 307.3 0.1 1.9e-91 306.9 0.1 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 KXS99871.1 - 2.7e-35 119.8 16.5 1.8e-07 31.8 0.3 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXS99871.1 - 5.5e-07 29.8 0.6 0.026 14.8 0.0 5.2 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXS99871.1 - 0.038 12.6 5.7 2.4 6.7 0.1 3.4 2 1 1 3 3 3 0 Nucleoporin Nup120/160 CRISPR_Cas2 PF09827.9 KXS99871.1 - 0.041 14.1 0.2 1.6 9.0 0.0 3.1 3 0 0 3 3 3 0 CRISPR associated protein Cas2 Gpr1_Fun34_YaaH PF01184.19 KXS99872.1 - 8e-30 104.0 14.7 1.1e-29 103.6 14.7 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Cir_N PF10197.9 KXS99873.1 - 2.6e-07 30.7 3.6 2.6e-07 30.7 3.6 5.4 6 1 1 7 7 7 1 N-terminal domain of CBF1 interacting co-repressor CIR MFS_1 PF07690.16 KXS99874.1 - 1.2e-35 123.1 28.6 1.2e-35 123.1 28.6 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily LCAT PF02450.15 KXS99875.1 - 7.3e-104 348.0 0.0 8.9e-104 347.8 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF900 PF05990.12 KXS99875.1 - 0.047 13.2 0.0 0.076 12.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Lipase_2 PF01674.18 KXS99875.1 - 0.061 12.8 0.0 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 Lipase (class 2) DUF1749 PF08538.10 KXS99875.1 - 0.18 10.8 0.0 0.3 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Sulfotransfer_4 PF17784.1 KXS99876.1 - 3.7e-54 183.8 0.0 4.4e-54 183.6 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KXS99876.1 - 8e-07 29.7 0.4 1.9e-05 25.2 0.0 2.3 1 1 1 2 2 2 1 Sulfotransferase family Sulfotransfer_4 PF17784.1 KXS99877.1 - 3.7e-54 183.8 0.0 4.4e-54 183.6 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KXS99877.1 - 8e-07 29.7 0.4 1.9e-05 25.2 0.0 2.3 1 1 1 2 2 2 1 Sulfotransferase family Sulfotransfer_4 PF17784.1 KXS99878.1 - 3.7e-54 183.8 0.0 4.4e-54 183.6 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KXS99878.1 - 8e-07 29.7 0.4 1.9e-05 25.2 0.0 2.3 1 1 1 2 2 2 1 Sulfotransferase family Na_Ca_ex PF01699.24 KXS99879.1 - 3.1e-13 50.0 22.3 8.7e-09 35.5 2.0 3.2 3 0 0 3 3 3 3 Sodium/calcium exchanger protein CPP1-like PF11833.8 KXS99879.1 - 3.8 7.1 7.1 0.7 9.5 2.8 2.0 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Sulfotransfer_4 PF17784.1 KXS99880.1 - 3.7e-54 183.8 0.0 4.4e-54 183.6 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KXS99880.1 - 8e-07 29.7 0.4 1.9e-05 25.2 0.0 2.3 1 1 1 2 2 2 1 Sulfotransferase family zf-RING_2 PF13639.6 KXS99881.1 - 0.0085 16.4 14.9 0.014 15.7 14.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 KXS99881.1 - 0.023 14.7 6.2 0.046 13.8 6.2 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KXS99881.1 - 0.08 12.8 11.1 1.9 8.4 5.6 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KXS99881.1 - 1.3 9.0 12.1 2.4 8.2 12.1 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 KXS99881.1 - 9.2 6.2 10.8 23 5.0 10.8 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CFEM PF05730.11 KXS99882.1 - 1.1e-10 41.4 7.5 1.9e-10 40.7 7.5 1.4 1 0 0 1 1 1 1 CFEM domain Acetyltransf_1 PF00583.25 KXS99883.1 - 4.4e-18 65.6 0.0 6.3e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXS99883.1 - 2.5e-11 43.6 0.0 4.2e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXS99883.1 - 2.9e-10 40.4 0.0 5.3e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KXS99883.1 - 3.5e-08 34.2 0.0 5.8e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXS99883.1 - 4.7e-08 32.9 0.0 7.5e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 KXS99883.1 - 1.4e-05 24.8 0.0 2.4e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXS99883.1 - 3.2e-05 24.0 0.7 0.0001 22.4 0.1 2.1 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXS99883.1 - 0.00083 19.4 0.0 0.0015 18.6 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase GNAT_acetyltran PF12746.7 KXS99883.1 - 0.026 14.1 0.0 0.036 13.6 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase Acetyltransf_4 PF13420.7 KXS99883.1 - 0.038 14.1 0.0 0.051 13.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 KXS99883.1 - 0.086 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Rox3 PF08633.10 KXS99884.1 - 0.079 13.2 0.0 0.087 13.1 0.0 1.0 1 0 0 1 1 1 0 Rox3 mediator complex subunit GMC_oxred_N PF00732.19 KXS99886.1 - 2.6e-54 184.6 0.0 3.6e-54 184.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXS99886.1 - 1.3e-29 103.6 0.0 2.3e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DnaJ_C PF01556.18 KXS99887.1 - 1.3e-25 90.3 0.0 1.8e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KXS99887.1 - 1.2e-23 83.0 4.4 2e-23 82.3 4.4 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KXS99887.1 - 4.8e-13 49.3 18.7 8.6e-13 48.4 18.7 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KXS99887.1 - 2.6e-07 30.5 6.6 0.00042 20.2 1.2 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KXS99887.1 - 0.00019 21.4 6.2 0.15 12.1 1.5 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TackOD1 PF18551.1 KXS99887.1 - 0.054 13.2 7.5 0.27 10.9 0.6 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 Biotin_lipoyl_2 PF13533.6 KXS99887.1 - 0.18 11.7 0.5 0.42 10.5 0.5 1.6 1 0 0 1 1 1 0 Biotin-lipoyl like Lar_restr_allev PF14354.6 KXS99887.1 - 0.61 10.5 10.4 1.5 9.3 2.6 3.3 1 1 2 3 3 3 0 Restriction alleviation protein Lar A2L_zn_ribbon PF08792.10 KXS99887.1 - 2.8 7.8 14.6 1.3 8.9 0.1 3.9 4 0 0 4 4 4 0 A2L zinc ribbon domain DZR PF12773.7 KXS99887.1 - 7.1 6.7 12.9 32 4.6 13.0 1.9 1 1 0 1 1 1 0 Double zinc ribbon RRM_1 PF00076.22 KXS99889.1 - 1.5e-14 53.5 0.0 2.5e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) XS PF03468.14 KXS99889.1 - 0.2 11.9 2.7 0.14 12.4 0.3 2.1 2 1 0 2 2 2 0 XS domain MobL PF18555.1 KXS99890.1 - 0.072 12.3 13.8 0.16 11.2 13.8 1.5 1 0 0 1 1 1 0 MobL relaxases V_ATPase_I PF01496.19 KXS99890.1 - 0.38 8.6 14.7 0.63 7.9 13.6 1.8 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Acyl-CoA_ox_N PF14749.6 KXS99890.1 - 0.94 10.0 9.2 0.094 13.3 2.3 2.5 2 0 0 2 2 2 0 Acyl-coenzyme A oxidase N-terminal Borrelia_P83 PF05262.11 KXS99890.1 - 4.4 5.7 23.3 6.7 5.1 23.3 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Peptidase_M2 PF01401.18 KXS99890.1 - 4.9 5.7 10.0 7.4 5.1 10.0 1.2 1 0 0 1 1 1 0 Angiotensin-converting enzyme MFS_1 PF07690.16 KXS99892.1 - 9.5e-37 126.7 52.5 2.5e-33 115.5 31.8 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Amino_oxidase PF01593.24 KXS99893.1 - 1.4e-57 196.0 0.0 1.6e-57 195.8 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Ribonuc_L-PSP PF01042.21 KXS99893.1 - 1.7e-14 53.8 0.0 3.6e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Endoribonuclease L-PSP NAD_binding_8 PF13450.6 KXS99893.1 - 4e-13 49.4 0.7 1.1e-12 47.9 0.2 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXS99893.1 - 4.4e-08 32.6 1.4 6.9e-08 32.0 1.4 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KXS99893.1 - 1.5e-07 31.1 0.3 2.1e-07 30.7 0.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KXS99893.1 - 1.6e-07 30.7 0.4 0.00014 21.1 0.5 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Thi4 PF01946.17 KXS99893.1 - 2.2e-06 27.1 0.1 4.4e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KXS99893.1 - 2.4e-06 27.4 0.0 4.7e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KXS99893.1 - 0.00023 20.4 0.3 0.0004 19.6 0.3 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 KXS99893.1 - 0.00026 19.8 1.2 0.0015 17.3 0.3 2.0 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.6 KXS99893.1 - 0.00027 21.0 0.9 0.16 12.0 0.1 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KXS99893.1 - 0.00045 19.5 0.0 0.00084 18.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXS99893.1 - 0.00049 19.5 0.1 0.24 10.6 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXS99893.1 - 0.0022 17.3 0.7 0.0037 16.6 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KXS99893.1 - 0.031 14.8 0.1 0.088 13.4 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KXS99893.1 - 0.058 12.7 0.2 0.11 11.8 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Metallophos PF00149.28 KXS99894.1 - 6.2e-12 46.4 0.5 1.1e-11 45.7 0.5 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXS99894.1 - 1.2e-06 28.9 0.2 1e-05 25.8 0.2 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ribonuc_L-PSP PF01042.21 KXS99895.1 - 7.2e-10 38.9 0.0 9e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP EKLF_TAD1 PF16832.5 KXS99895.1 - 0.0012 18.6 0.1 0.0025 17.6 0.1 1.5 1 0 0 1 1 1 1 Erythroid krueppel-like transcription factor, transactivation 1 T_cell_tran_alt PF15128.6 KXS99900.1 - 0.98 9.3 3.6 7.4 6.5 0.2 2.4 1 1 1 2 2 2 0 T-cell leukemia translocation-altered Abhydrolase_4 PF08386.10 KXS99901.1 - 2.8e-15 56.3 0.0 8.7e-15 54.7 0.0 1.8 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.20 KXS99901.1 - 6e-11 42.5 0.0 8.2e-10 38.8 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 KXS99902.1 - 4.6e-21 75.6 0.0 1.5e-16 60.8 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KXS99902.1 - 1.7e-16 60.2 0.2 5.3e-16 58.6 0.0 1.9 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_6 PF12697.7 KXS99902.1 - 0.002 18.8 0.1 0.08 13.5 0.0 2.6 1 1 1 3 3 3 1 Alpha/beta hydrolase family MFS_1 PF07690.16 KXS99906.1 - 9.7e-17 60.9 63.4 3.9e-09 35.9 28.4 3.4 2 1 1 3 3 3 2 Major Facilitator Superfamily CRM1_repeat_3 PF18787.1 KXS99911.1 - 0.034 14.3 0.1 0.083 13.0 0.1 1.6 1 0 0 1 1 1 0 CRM1 / Exportin repeat 3 F-box PF00646.33 KXS99912.1 - 2.5e-07 30.4 0.1 0.00012 21.9 0.0 2.5 2 0 0 2 2 2 2 F-box domain F-box-like PF12937.7 KXS99912.1 - 1.3e-06 28.2 0.2 0.0018 18.1 0.1 2.5 2 0 0 2 2 2 2 F-box-like DUF4472 PF14739.6 KXS99914.1 - 0.054 14.2 0.7 0.067 13.9 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) p450 PF00067.22 KXS99916.1 - 4.3e-34 118.1 0.0 5.6e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TRI12 PF06609.13 KXS99917.1 - 5.3e-25 87.9 25.5 6.5e-25 87.6 25.5 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KXS99917.1 - 5.4e-20 71.6 51.4 5.4e-20 71.6 51.4 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXS99917.1 - 9.1e-09 34.7 10.3 9.1e-09 34.7 10.3 3.5 1 1 0 3 3 3 2 Sugar (and other) transporter MipA PF06629.12 KXS99917.1 - 0.061 13.6 0.7 0.48 10.6 0.2 2.2 2 0 0 2 2 2 0 MltA-interacting protein MipA Glyco_hydro_17 PF00332.18 KXS99918.1 - 1.8e-06 27.8 0.0 2.6e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 RRM_2 PF04059.12 KXS99919.1 - 9.9e-12 44.9 0.0 1.5e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif 2 DUF4448 PF14610.6 KXS99923.1 - 0.053 13.3 0.0 0.085 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) TMEM154 PF15102.6 KXS99923.1 - 0.057 13.3 7.7 0.41 10.5 7.7 2.2 1 1 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.6 KXS99923.1 - 0.066 14.1 0.0 0.15 13.0 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3377 PF11857.8 KXS99923.1 - 0.095 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Shisa PF13908.6 KXS99923.1 - 8.2 6.6 8.8 1.5 9.0 1.1 2.7 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Melibiase PF02065.18 KXS99924.1 - 8.9e-129 429.4 0.0 1.1e-128 429.0 0.0 1.1 1 0 0 1 1 1 1 Melibiase Glyco_hydro_36N PF16875.5 KXS99924.1 - 1.4e-76 257.4 0.0 2.4e-76 256.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 N-terminal domain Glyco_hydro_36C PF16874.5 KXS99924.1 - 5.2e-22 78.1 0.0 1.1e-21 77.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 C-terminal domain GHL10 PF02638.15 KXS99924.1 - 0.0012 18.0 0.1 0.002 17.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase-like 10 DUF829 PF05705.14 KXS99925.1 - 1.1e-31 110.6 0.0 1.6e-31 110.1 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_1 PF00561.20 KXS99927.1 - 2.9e-16 59.9 0.0 5.7e-16 58.9 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXS99927.1 - 3.5e-11 44.1 0.2 3.7e-09 37.5 0.0 2.4 2 1 1 3 3 3 1 Alpha/beta hydrolase family Chlorophyllase PF07224.11 KXS99927.1 - 0.0086 15.1 0.1 0.29 10.1 0.0 2.4 2 1 0 2 2 2 1 Chlorophyllase Asp PF00026.23 KXS99928.1 - 4.7e-69 233.2 0.2 5.7e-69 232.9 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXS99928.1 - 5.9e-13 49.4 0.3 3.8e-11 43.5 0.3 2.6 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KXS99928.1 - 0.00077 20.1 0.1 4.2 8.1 0.0 3.5 2 1 0 2 2 2 2 Aspartyl protease Peroxidase_2 PF01328.17 KXS99929.1 - 3.4e-46 158.2 0.0 4.8e-46 157.7 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 Peroxidase_2 PF01328.17 KXS99931.1 - 7.4e-18 65.8 0.0 1.2e-17 65.1 0.0 1.3 1 0 0 1 1 1 1 Peroxidase, family 2 WbqC PF08889.11 KXS99938.1 - 0.011 15.7 0.0 0.011 15.6 0.0 1.1 1 0 0 1 1 1 0 WbqC-like protein family Peptidase_M48_N PF16491.5 KXS99944.1 - 1.2e-63 214.3 7.6 3e-63 213.0 7.0 2.0 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 KXS99944.1 - 8.5e-43 146.4 0.3 3.2e-42 144.5 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M48 Cyclase PF04199.13 KXS99944.1 - 1.4e-14 54.5 0.1 4.6e-14 52.8 0.0 1.9 2 0 0 2 2 2 1 Putative cyclase Peptidase_M56 PF05569.11 KXS99944.1 - 0.021 14.0 0.2 0.07 12.3 0.2 1.7 1 1 0 1 1 1 0 BlaR1 peptidase M56 NTP_transf_3 PF12804.7 KXS99944.1 - 0.073 13.4 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 MobA-like NTP transferase domain DUF2268 PF10026.9 KXS99944.1 - 0.077 12.6 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) SprT-like PF10263.9 KXS99944.1 - 0.11 12.3 0.0 0.31 10.9 0.0 1.7 1 0 0 1 1 1 0 SprT-like family Sugar_tr PF00083.24 KXS99945.1 - 5.1e-96 322.3 19.7 6.3e-96 322.0 19.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXS99945.1 - 8.6e-29 100.6 29.3 8.6e-29 100.6 29.3 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Ceramidase PF05875.12 KXS99945.1 - 0.13 11.7 1.2 0.21 11.0 1.2 1.4 1 0 0 1 1 1 0 Ceramidase AMP-binding PF00501.28 KXS99946.1 - 3.5e-98 329.0 0.0 4.2e-98 328.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXS99946.1 - 9.8e-15 55.3 0.2 2.5e-14 54.0 0.2 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Hydrolase_4 PF12146.8 KXS99947.1 - 1.3e-20 73.7 0.0 2.3e-20 72.9 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXS99947.1 - 3.8e-18 66.1 0.0 2.5e-15 56.8 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXS99947.1 - 1.5e-17 64.9 0.0 2e-17 64.5 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 KXS99947.1 - 1.6e-06 27.1 0.0 2.6e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Ndr family Abhydrolase_2 PF02230.16 KXS99947.1 - 2.7e-06 27.4 0.0 0.00038 20.3 0.0 2.1 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase Thioesterase PF00975.20 KXS99947.1 - 6.9e-06 26.3 0.0 8.7e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain DUF1749 PF08538.10 KXS99947.1 - 0.00027 20.1 0.0 0.00051 19.2 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1749) Ser_hydrolase PF06821.13 KXS99947.1 - 0.0005 20.0 0.1 0.0016 18.3 0.1 2.0 1 1 0 1 1 1 1 Serine hydrolase Esterase PF00756.20 KXS99947.1 - 0.0012 18.5 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.13 KXS99947.1 - 0.0055 16.5 0.1 0.01 15.6 0.0 1.4 2 0 0 2 2 2 1 PGAP1-like protein LIDHydrolase PF10230.9 KXS99947.1 - 0.0077 15.8 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase DUF1057 PF06342.12 KXS99947.1 - 0.015 14.4 0.0 0.027 13.5 0.0 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_5 PF12695.7 KXS99947.1 - 0.018 14.8 0.0 0.28 10.9 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family FSH1 PF03959.13 KXS99947.1 - 0.032 13.9 0.2 0.24 11.1 0.0 2.3 2 1 0 2 2 2 0 Serine hydrolase (FSH1) DLH PF01738.18 KXS99947.1 - 0.044 13.3 0.0 0.18 11.4 0.0 1.8 2 0 0 2 2 2 0 Dienelactone hydrolase family WD40 PF00400.32 KXS99948.1 - 9.2e-49 162.4 19.8 4.4e-05 24.2 0.0 12.6 11 2 0 11 11 11 8 WD domain, G-beta repeat Utp13 PF08625.11 KXS99948.1 - 5.6e-43 146.2 0.2 1.2e-42 145.2 0.2 1.6 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.8 KXS99948.1 - 9.2e-08 31.2 18.2 0.51 8.9 0.0 7.5 4 2 3 8 8 8 5 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KXS99948.1 - 4.8e-07 30.0 5.6 1.1 9.6 0.1 6.7 6 1 2 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 KXS99948.1 - 0.0026 16.8 1.6 0.19 10.6 0.2 3.0 3 0 0 3 3 3 2 Partner and localizer of BRCA2 WD40 domain Nucleoporin_N PF08801.11 KXS99948.1 - 0.071 11.9 2.4 19 3.9 0.4 4.0 3 2 1 4 4 4 0 Nup133 N terminal like SF3b10 PF07189.11 KXS99948.1 - 0.12 12.6 0.9 16 5.7 0.0 2.6 2 0 0 2 2 2 0 Splicing factor 3B subunit 10 (SF3b10) Sfi1 PF08457.10 KXS99949.1 - 5.2e-07 28.6 7.5 7.8e-07 28.0 7.5 1.2 1 0 0 1 1 1 1 Sfi1 spindle body protein BTB PF00651.31 KXS99950.1 - 0.023 14.9 0.0 0.045 14.0 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain DUF5538 PF17692.1 KXS99950.1 - 0.037 14.1 1.5 0.053 13.6 0.2 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5538) Proteasome PF00227.26 KXS99951.1 - 1.3e-37 129.1 0.0 1.5e-37 128.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit CLZ PF16526.5 KXS99954.1 - 0.0015 18.8 5.5 0.0022 18.3 5.5 1.2 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FlxA PF14282.6 KXS99954.1 - 0.0054 16.7 4.6 0.0062 16.5 4.6 1.1 1 0 0 1 1 1 1 FlxA-like protein KxDL PF10241.9 KXS99954.1 - 0.0067 16.7 1.2 0.008 16.4 1.0 1.3 1 1 0 1 1 1 1 Uncharacterized conserved protein GAS PF13851.6 KXS99954.1 - 0.011 15.1 3.7 0.014 14.8 3.7 1.0 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Imm49 PF15575.6 KXS99954.1 - 0.014 15.2 1.1 0.015 15.0 1.1 1.1 1 0 0 1 1 1 0 Immunity protein 49 HAUS6_N PF14661.6 KXS99954.1 - 0.015 14.9 1.5 0.015 14.9 1.5 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Serine_rich PF08824.10 KXS99954.1 - 0.017 15.1 0.4 0.022 14.7 0.4 1.1 1 0 0 1 1 1 0 Serine rich protein interaction domain zf-CpG_bind_C PF12269.8 KXS99954.1 - 0.052 13.3 1.0 0.057 13.2 1.0 1.0 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain TssO PF17561.2 KXS99954.1 - 0.087 12.9 0.3 0.1 12.7 0.3 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssO Get5_C PF18514.1 KXS99954.1 - 0.11 12.3 1.3 5.8 6.7 0.2 2.2 2 0 0 2 2 2 0 Get5 C-terminal domain Sec34 PF04136.15 KXS99954.1 - 0.11 12.4 0.9 0.12 12.2 0.9 1.1 1 0 0 1 1 1 0 Sec34-like family MtrG PF04210.13 KXS99954.1 - 0.13 12.1 0.3 0.23 11.3 0.2 1.4 1 1 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G APG6_N PF17675.1 KXS99954.1 - 0.18 12.3 9.0 0.2 12.2 9.0 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region ThrE PF06738.12 KXS99954.1 - 0.31 10.4 0.1 0.38 10.1 0.1 1.1 1 0 0 1 1 1 0 Putative threonine/serine exporter OmpH PF03938.14 KXS99954.1 - 0.4 11.0 8.8 0.46 10.8 8.8 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) GTA_holin_3TM PF11351.8 KXS99954.1 - 1.3 9.5 4.0 1.6 9.2 4.0 1.1 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release DUF4387 PF14330.6 KXS99955.1 - 1.1e-37 128.6 0.0 2.4e-37 127.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) AtuA PF07287.11 KXS99955.1 - 8.7e-17 60.9 0.1 7.1e-16 57.9 0.1 2.0 1 1 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Methyltransf_16 PF10294.9 KXS99957.1 - 1.4e-43 148.7 0.0 2e-43 148.2 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 KXS99957.1 - 4.5e-07 29.8 0.0 1.3e-06 28.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KXS99957.1 - 0.00062 19.4 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KXS99957.1 - 0.0022 18.7 0.0 0.0098 16.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXS99957.1 - 0.0029 18.3 0.0 0.0069 17.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KXS99957.1 - 0.063 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain DAHP_synth_1 PF00793.20 KXS99958.1 - 1.8e-99 332.1 0.0 2.3e-99 331.7 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family FMO-like PF00743.19 KXS99959.1 - 4.7e-17 61.6 0.3 3.4e-16 58.8 0.1 2.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KXS99959.1 - 3.5e-13 49.4 0.0 5.1e-10 39.1 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXS99959.1 - 5.8e-13 48.8 2.2 8.4e-13 48.2 0.2 2.3 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXS99959.1 - 6.2e-08 32.2 0.1 8.8e-05 21.9 0.0 2.7 3 0 0 3 3 3 2 Thi4 family NAD_binding_8 PF13450.6 KXS99959.1 - 3.8e-07 30.2 0.0 0.0002 21.6 0.0 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXS99959.1 - 5.9e-07 29.4 0.2 0.17 11.4 0.0 4.0 4 1 0 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 KXS99959.1 - 7.7e-07 28.6 0.1 3e-05 23.3 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KXS99959.1 - 7e-05 23.3 1.2 0.011 16.2 0.0 3.1 4 0 0 4 4 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXS99959.1 - 0.0044 16.1 0.0 4.8 6.1 0.0 3.1 3 0 0 3 3 3 1 Lycopene cyclase protein Mqo PF06039.15 KXS99959.1 - 0.0071 14.9 0.1 2.2 6.7 0.0 2.5 3 0 0 3 3 3 2 Malate:quinone oxidoreductase (Mqo) FAD_binding_2 PF00890.24 KXS99959.1 - 0.025 13.7 0.1 0.67 9.0 0.0 2.4 2 0 0 2 2 2 0 FAD binding domain HTH_Crp_2 PF13545.6 KXS99959.1 - 0.094 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Wzy_C_2 PF11846.8 KXS99959.1 - 0.1 12.5 0.0 0.77 9.6 0.0 2.1 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal Shikimate_DH PF01488.20 KXS99959.1 - 0.18 11.9 0.1 2.1 8.4 0.0 2.5 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 KXS99959.1 - 0.18 11.8 1.3 82 3.2 0.1 3.9 4 0 0 4 4 4 0 FAD-NAD(P)-binding Sacchrp_dh_NADP PF03435.18 KXS99959.1 - 0.24 11.6 1.5 13 6.0 0.0 2.7 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain Zn_clus PF00172.18 KXS99960.1 - 0.0015 18.7 11.8 0.0031 17.6 11.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cep3 PF16846.5 KXS99960.1 - 0.0064 15.0 0.0 0.01 14.3 0.0 1.2 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit B Aa_trans PF01490.18 KXS99961.1 - 1.2e-81 274.6 34.9 1.4e-81 274.4 34.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Glyco_hydro_32N PF00251.20 KXS99962.1 - 2e-76 257.5 3.2 2.6e-76 257.1 3.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KXS99962.1 - 2.7e-09 37.2 0.1 4.9e-09 36.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Pam17 PF08566.10 KXS99963.1 - 6.3e-60 201.8 0.0 8.9e-60 201.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 P19Arf_N PF07392.12 KXS99963.1 - 0.78 10.2 4.1 17 6.0 0.1 3.3 3 0 0 3 3 3 0 Cyclin-dependent kinase inhibitor 2a p19Arf N-terminus Pam17 PF08566.10 KXS99964.1 - 6.3e-60 201.8 0.0 8.9e-60 201.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 P19Arf_N PF07392.12 KXS99964.1 - 0.78 10.2 4.1 17 6.0 0.1 3.3 3 0 0 3 3 3 0 Cyclin-dependent kinase inhibitor 2a p19Arf N-terminus Pam17 PF08566.10 KXS99965.1 - 6.3e-60 201.8 0.0 8.9e-60 201.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 P19Arf_N PF07392.12 KXS99965.1 - 0.78 10.2 4.1 17 6.0 0.1 3.3 3 0 0 3 3 3 0 Cyclin-dependent kinase inhibitor 2a p19Arf N-terminus MT0933_antitox PF14013.6 KXS99966.1 - 0.81 10.0 6.6 1.4 9.3 2.3 3.0 2 1 0 2 2 2 0 MT0933-like antitoxin protein NARP1 PF12569.8 KXS99967.1 - 1 8.2 18.8 0.83 8.5 4.3 2.2 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 Peptidase_S49_N PF08496.10 KXS99967.1 - 5.7 7.0 10.5 0.65 10.1 0.9 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Ntox3 PF15536.6 KXS99968.1 - 0.00079 19.5 0.0 0.0011 19.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial toxin 3 zf-RING_2 PF13639.6 KXS99969.1 - 4.5e-11 42.9 11.7 8.1e-11 42.1 11.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KXS99969.1 - 8.8e-10 38.3 7.4 1.5e-09 37.5 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXS99969.1 - 1.3e-09 37.8 11.2 2.4e-09 36.9 11.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXS99969.1 - 9.9e-08 31.7 11.3 1.9e-07 30.8 11.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXS99969.1 - 7.9e-07 29.3 7.5 2e-06 28.0 7.5 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KXS99969.1 - 7.9e-07 28.9 9.6 1.4e-06 28.1 9.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXS99969.1 - 1.2e-06 28.4 9.7 2.9e-06 27.2 9.7 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KXS99969.1 - 3.6e-06 26.7 8.4 1.1e-05 25.2 8.5 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KXS99969.1 - 0.0001 22.2 3.4 0.00025 21.0 3.4 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KXS99969.1 - 0.0084 16.3 11.9 0.018 15.2 11.9 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KXS99969.1 - 0.012 15.4 8.7 0.054 13.3 8.8 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 KXS99969.1 - 0.098 12.3 6.3 0.22 11.2 6.3 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF1272 PF06906.11 KXS99969.1 - 0.12 12.5 5.6 0.24 11.5 5.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zinc-ribbons_6 PF07191.12 KXS99969.1 - 0.27 11.3 8.2 0.48 10.4 8.2 1.4 1 0 0 1 1 1 0 zinc-ribbons DNA_ligase_ZBD PF03119.16 KXS99969.1 - 0.39 10.8 2.6 12 6.0 0.1 2.7 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain zf-P11 PF03854.14 KXS99969.1 - 0.65 9.7 9.1 2.7 7.7 9.1 1.9 1 1 0 1 1 1 0 P-11 zinc finger zf-RING_6 PF14835.6 KXS99969.1 - 1.1 9.2 7.0 0.87 9.5 1.3 2.3 1 1 1 2 2 2 0 zf-RING of BARD1-type protein DZR PF12773.7 KXS99969.1 - 1.5 8.9 6.7 4.8 7.3 6.8 1.8 1 1 0 1 1 1 0 Double zinc ribbon IBR PF01485.21 KXS99969.1 - 1.7 9.0 9.3 4.7 7.5 9.3 1.8 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain zf-RING_11 PF17123.5 KXS99969.1 - 1.9 8.3 6.0 4.7 7.0 6.0 1.8 1 0 0 1 1 1 0 RING-like zinc finger OrfB_Zn_ribbon PF07282.11 KXS99969.1 - 5.6 7.0 6.7 4.8 7.2 0.2 2.3 1 1 1 2 2 2 0 Putative transposase DNA-binding domain IF-2B PF01008.17 KXS99970.1 - 1.5e-71 240.9 0.8 1.9e-71 240.6 0.8 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family BNR_2 PF13088.6 KXS99972.1 - 7e-06 25.5 0.2 0.07 12.4 0.0 2.6 2 1 0 2 2 2 2 BNR repeat-like domain adh_short_C2 PF13561.6 KXS99974.1 - 8.3e-47 159.7 0.0 1e-46 159.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXS99974.1 - 1.5e-33 115.9 0.0 1.8e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase 3HCDH_N PF02737.18 KXS99974.1 - 0.042 13.7 0.1 0.15 11.9 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MFS_1 PF07690.16 KXS99975.1 - 1.3e-35 123.0 29.5 1.3e-35 123.0 29.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Pam17 PF08566.10 KXS99975.1 - 0.011 15.6 0.2 3.8 7.3 0.0 2.6 3 0 0 3 3 3 0 Mitochondrial import protein Pam17 DUF962 PF06127.11 KXS99975.1 - 0.016 15.3 0.7 0.053 13.6 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF962) MFS_1 PF07690.16 KXS99976.1 - 1.3e-35 123.0 29.5 1.3e-35 123.0 29.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Pam17 PF08566.10 KXS99976.1 - 0.011 15.6 0.2 3.8 7.3 0.0 2.6 3 0 0 3 3 3 0 Mitochondrial import protein Pam17 DUF962 PF06127.11 KXS99976.1 - 0.016 15.3 0.7 0.053 13.6 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF962) MFS_1 PF07690.16 KXS99977.1 - 1.3e-35 123.0 29.5 1.3e-35 123.0 29.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Pam17 PF08566.10 KXS99977.1 - 0.011 15.6 0.2 3.8 7.3 0.0 2.6 3 0 0 3 3 3 0 Mitochondrial import protein Pam17 DUF962 PF06127.11 KXS99977.1 - 0.016 15.3 0.7 0.053 13.6 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF962) Ribosomal_S13 PF00416.22 KXS99978.1 - 1.1e-20 74.3 1.2 2.2e-18 66.9 1.2 2.1 1 1 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 KXS99978.1 - 0.0029 16.4 0.0 0.0036 16.1 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) cobW PF02492.19 KXS99980.1 - 1.4e-34 119.3 0.1 2.4e-34 118.5 0.1 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 KXS99980.1 - 6.9e-07 29.2 0.0 1.9e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B RsgA_GTPase PF03193.16 KXS99980.1 - 0.00067 19.6 0.0 0.19 11.6 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase Viral_helicase1 PF01443.18 KXS99980.1 - 0.0031 17.3 0.0 0.007 16.1 0.0 1.6 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 KXS99980.1 - 0.0043 17.4 0.0 0.0043 17.4 0.0 2.4 3 1 0 3 3 2 1 AAA ATPase domain SRP54 PF00448.22 KXS99980.1 - 0.0091 15.6 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_22 PF13401.6 KXS99980.1 - 0.012 15.9 2.2 0.021 15.1 0.1 2.6 3 1 0 3 3 3 0 AAA domain AAA_14 PF13173.6 KXS99980.1 - 0.014 15.4 0.1 0.082 12.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain CobW_C PF07683.14 KXS99980.1 - 0.038 13.9 0.0 0.099 12.6 0.0 1.7 1 0 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain ABC_tran PF00005.27 KXS99980.1 - 0.039 14.5 0.5 0.14 12.7 0.0 2.2 2 1 0 2 2 2 0 ABC transporter AAA_28 PF13521.6 KXS99980.1 - 0.039 14.2 1.3 0.52 10.5 0.0 2.8 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 KXS99980.1 - 0.066 13.1 0.1 0.19 11.6 0.1 1.8 1 0 0 1 1 1 0 NTPase Adeno_IVa2 PF02456.15 KXS99980.1 - 0.068 12.0 0.2 4 6.1 0.0 2.4 2 0 0 2 2 2 0 Adenovirus IVa2 protein ATPase_2 PF01637.18 KXS99980.1 - 0.086 12.7 0.0 0.086 12.7 0.0 1.8 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea CbiA PF01656.23 KXS99980.1 - 0.12 12.4 0.2 0.4 10.8 0.0 2.0 2 1 1 3 3 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_11 PF13086.6 KXS99980.1 - 0.49 10.1 8.1 0.67 9.7 0.1 3.1 3 1 0 3 3 3 0 AAA domain DUF4632 PF15451.6 KXS99980.1 - 5.5 7.1 6.4 20 5.4 6.4 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) GTP_EFTU PF00009.27 KXS99981.1 - 5.5e-07 29.3 0.1 0.014 14.9 0.0 3.0 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KXS99981.1 - 6e-07 29.7 0.0 2.2e-06 27.8 0.0 2.0 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KXS99981.1 - 0.00014 22.0 0.0 0.66 10.1 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXS99981.1 - 0.00051 20.0 0.0 0.16 11.9 0.0 3.3 3 1 1 4 4 4 1 RsgA GTPase DUF87 PF01935.17 KXS99981.1 - 0.0011 19.1 1.0 0.038 14.1 0.0 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain TryThrA_C PF12319.8 KXS99981.1 - 0.0079 15.7 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 Tryptophan-Threonine-rich plasmodium antigen C terminal AAA_16 PF13191.6 KXS99981.1 - 0.014 15.8 0.4 0.11 12.9 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 KXS99981.1 - 0.025 15.1 0.0 0.16 12.5 0.0 2.4 2 0 0 2 2 2 0 ABC transporter SRP54 PF00448.22 KXS99981.1 - 0.099 12.3 0.1 6.4 6.4 0.1 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ADK PF00406.22 KXS99983.1 - 8.1e-48 162.4 0.0 1e-47 162.1 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KXS99983.1 - 6.5e-38 130.2 0.0 1e-37 129.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXS99983.1 - 1.2e-10 42.0 0.0 2.9e-10 40.8 0.0 1.5 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 KXS99983.1 - 4.2e-06 26.6 0.3 0.073 12.8 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_33 PF13671.6 KXS99983.1 - 2e-05 24.8 0.0 6.6e-05 23.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain PAS_7 PF12860.7 KXS99983.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.5 2 0 0 2 2 2 0 PAS fold Asp PF00026.23 KXS99986.1 - 1.3e-46 159.5 0.0 4.8e-46 157.6 0.0 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease HA2 PF04408.23 KXS99986.1 - 0.058 13.7 0.2 0.25 11.6 0.0 2.1 2 0 0 2 2 2 0 Helicase associated domain (HA2) Pro_isomerase PF00160.21 KXS99987.1 - 6.4e-49 166.3 0.2 9.2e-49 165.7 0.2 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SnoaL_4 PF13577.6 KXS99988.1 - 7.3e-15 55.2 0.0 9.6e-15 54.8 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.6 KXS99988.1 - 0.031 14.5 0.1 0.065 13.5 0.1 1.5 1 1 0 1 1 1 0 SnoaL-like domain TMF_DNA_bd PF12329.8 KXT00006.1 - 0.00053 19.9 15.0 0.00053 19.9 15.0 19.1 8 3 13 22 22 22 6 TATA element modulatory factor 1 DNA binding Phage_GP20 PF06810.11 KXT00006.1 - 0.0031 17.3 10.6 0.0031 17.3 10.6 14.3 5 2 10 16 16 16 5 Phage minor structural protein GP20 DUF4743 PF15916.5 KXT00006.1 - 0.016 15.2 2.0 3.9 7.5 0.0 4.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4743) adh_short PF00106.25 KXT00007.1 - 4.2e-31 107.9 0.0 4.5e-23 81.7 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXT00007.1 - 6.8e-21 74.9 0.0 4.5e-15 55.9 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT00007.1 - 1.3e-11 44.8 0.0 2e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KXT00007.1 - 0.035 14.0 0.0 0.14 12.0 0.0 1.8 2 0 0 2 2 2 0 NAD(P)H-binding Mpt_N PF09176.11 KXT00007.1 - 0.093 12.9 0.0 1.6 8.9 0.0 2.6 2 1 1 3 3 3 0 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal Glyco_transf_90 PF05686.12 KXT00008.1 - 5e-22 78.3 1.2 7.2e-22 77.8 1.2 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 KXT00008.1 - 0.0026 18.1 0.4 0.0067 16.8 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 DUF5308 PF17233.2 KXT00009.1 - 0.01 16.0 0.1 0.014 15.7 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5308) TPR_2 PF07719.17 KXT00010.1 - 0.19 11.9 1.5 2.1 8.6 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat FAT PF02259.23 KXT00010.1 - 0.29 10.3 2.5 2.8 7.1 0.7 2.0 1 1 1 2 2 2 0 FAT domain CFEM PF05730.11 KXT00011.1 - 1.3e-09 38.0 2.4 2.4e-09 37.2 2.4 1.4 1 0 0 1 1 1 1 CFEM domain PAN_1 PF00024.26 KXT00012.1 - 0.00048 20.0 0.6 0.00075 19.4 0.6 1.3 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.12 KXT00012.1 - 0.00094 18.9 1.1 0.0016 18.2 1.1 1.4 1 0 0 1 1 1 1 PAN-like domain PAN_4 PF14295.6 KXT00012.1 - 0.033 14.1 1.6 0.048 13.6 0.7 1.7 2 0 0 2 2 2 0 PAN domain DUF2020 PF09449.10 KXT00012.1 - 0.051 13.4 0.0 0.18 11.6 0.0 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF2020) MANEC PF07502.14 KXT00012.1 - 0.064 13.5 0.1 0.095 13.0 0.1 1.3 1 0 0 1 1 1 0 MANEC domain Peptidase_S9 PF00326.21 KXT00013.1 - 4.5e-45 153.7 0.2 7.7e-45 153.0 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 KXT00013.1 - 3.7e-06 26.7 1.9 0.00059 19.7 0.1 3.7 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat MARVEL PF01284.23 KXT00013.1 - 0.00047 20.2 3.3 0.0011 19.0 3.3 1.6 1 0 0 1 1 1 1 Membrane-associating domain DUF2920 PF11144.8 KXT00013.1 - 0.1 11.8 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Ank_2 PF12796.7 KXT00014.1 - 6.3e-24 84.4 7.5 5.7e-11 42.9 0.4 5.3 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXT00014.1 - 2.9e-18 65.7 5.3 0.00012 22.3 0.3 5.8 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXT00014.1 - 5.1e-18 63.3 2.8 0.0042 17.5 0.0 7.5 7 0 0 7 7 7 4 Ankyrin repeat Ank_4 PF13637.6 KXT00014.1 - 8.7e-18 64.5 4.5 2.3e-05 24.9 0.0 5.3 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 KXT00014.1 - 4.4e-14 52.2 7.8 0.0088 16.5 0.1 6.7 6 0 0 6 6 6 3 Ankyrin repeat NACHT PF05729.12 KXT00014.1 - 9.6e-10 38.6 0.2 2e-09 37.6 0.2 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KXT00014.1 - 1.1e-05 25.9 1.9 2.1e-05 24.9 0.2 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KXT00014.1 - 0.00014 22.1 0.0 0.0005 20.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KXT00014.1 - 0.018 15.4 0.0 0.1 12.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KXT00014.1 - 0.033 13.5 0.0 0.5 9.6 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.6 KXT00014.1 - 0.085 13.0 0.0 0.43 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KXT00014.1 - 0.17 12.3 0.1 0.5 10.8 0.0 1.8 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) ABA_GPCR PF12430.8 KXT00015.1 - 7.8e-59 198.5 0.7 7.8e-59 198.5 0.7 2.2 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 KXT00015.1 - 4.6e-25 87.5 0.8 2.3e-24 85.3 0.2 2.2 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal ketoacyl-synt PF00109.26 KXT00016.1 - 4.2e-70 236.2 0.0 8.5e-70 235.2 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain HTH_51 PF18558.1 KXT00016.1 - 9e-32 108.8 0.0 1.9e-31 107.8 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain Ketoacyl-synt_C PF02801.22 KXT00016.1 - 1.2e-31 109.1 0.5 2.8e-31 108.0 0.5 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 KXT00016.1 - 1.1e-26 94.2 0.0 5.8e-23 81.9 0.0 2.3 2 0 0 2 2 2 2 Acyl transferase domain NAD_binding_4 PF07993.12 KXT00016.1 - 1.3e-24 86.8 0.0 2.2e-24 86.1 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein SAT PF16073.5 KXT00016.1 - 7.6e-15 55.3 5.5 2.6e-12 47.0 0.1 3.8 3 1 0 3 3 3 2 Starter unit:ACP transacylase in aflatoxin biosynthesis KAsynt_C_assoc PF16197.5 KXT00016.1 - 3e-12 47.0 0.3 1.8e-11 44.5 0.0 2.5 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 KXT00016.1 - 1.2e-11 44.8 1.0 2.7e-11 43.7 1.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_12 PF08242.12 KXT00016.1 - 5.5e-11 43.1 0.0 2.1e-10 41.2 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXT00016.1 - 2.9e-08 34.3 0.0 1.7e-07 31.9 0.0 2.5 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 KXT00016.1 - 4.5e-08 32.8 0.2 1.6e-07 31.0 0.0 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_23 PF13489.6 KXT00016.1 - 4.2e-07 29.9 0.0 9.2e-06 25.6 0.0 2.7 3 0 0 3 3 2 1 Methyltransferase domain Epimerase PF01370.21 KXT00016.1 - 1.4e-05 24.7 0.0 2.8e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PS-DH PF14765.6 KXT00016.1 - 5.5e-05 22.5 0.0 0.0001 21.6 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_11 PF08241.12 KXT00016.1 - 0.00011 22.7 0.0 0.00039 21.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXT00016.1 - 0.0029 17.4 0.0 0.012 15.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain KR PF08659.10 KXT00016.1 - 0.0076 16.2 0.0 0.026 14.4 0.0 1.9 2 0 0 2 2 1 1 KR domain Methyltransf_28 PF02636.17 KXT00016.1 - 0.049 13.3 0.0 0.099 12.2 0.0 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_33 PF10017.9 KXT00016.1 - 0.053 12.7 0.0 0.16 11.1 0.0 1.7 2 0 0 2 2 2 0 Histidine-specific methyltransferase, SAM-dependent Entericidin PF08085.11 KXT00017.1 - 0.12 12.4 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Entericidin EcnA/B family Neur_chan_memb PF02932.16 KXT00018.1 - 0.37 10.8 2.6 0.45 10.5 2.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SARAF PF06682.12 KXT00018.1 - 0.95 9.0 6.1 3.3 7.2 6.0 1.7 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF4078 PF13300.6 KXT00019.1 - 2e-28 98.5 14.3 2e-28 98.5 14.3 3.7 4 2 1 5 5 5 1 Domain of unknown function (DUF4078) PIG-Y PF15159.6 KXT00020.1 - 1.8e-21 76.8 6.3 3e-21 76.1 6.3 1.3 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y TLP-20 PF06088.11 KXT00020.1 - 7.2 6.5 5.9 9.8 6.0 1.8 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) PIG-Y PF15159.6 KXT00021.1 - 1.8e-21 76.8 6.3 3e-21 76.1 6.3 1.3 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y TLP-20 PF06088.11 KXT00021.1 - 7.2 6.5 5.9 9.8 6.0 1.8 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) FAD_binding_3 PF01494.19 KXT00024.1 - 1.1e-17 64.3 0.0 3.8e-17 62.6 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain YCII PF03795.14 KXT00024.1 - 4.6e-10 39.8 0.0 1.1e-09 38.5 0.0 1.6 1 0 0 1 1 1 1 YCII-related domain DAO PF01266.24 KXT00024.1 - 4.5e-05 23.2 3.8 0.03 13.9 4.0 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KXT00024.1 - 0.00017 21.0 0.0 0.00084 18.7 0.0 1.9 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXT00024.1 - 0.00056 20.1 3.0 0.00058 20.0 1.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KXT00024.1 - 0.0012 17.7 0.2 0.047 12.5 0.2 2.5 3 0 0 3 3 3 1 Tryptophan halogenase Pyr_redox PF00070.27 KXT00024.1 - 0.0049 17.4 0.4 0.016 15.7 0.4 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXT00024.1 - 0.028 13.7 0.0 0.76 8.9 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXT00024.1 - 0.051 13.6 3.2 2.2 8.3 1.2 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding Actin PF00022.19 KXT00025.1 - 1.7e-52 178.5 0.0 6.4e-27 94.2 0.0 2.4 1 1 1 2 2 2 2 Actin DUF695 PF05117.12 KXT00026.1 - 0.00047 20.3 0.0 0.00051 20.2 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF695) DUF4259 PF14078.6 KXT00026.1 - 0.007 17.1 0.2 0.01 16.6 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4259) DUF4519 PF15012.6 KXT00026.1 - 0.94 9.7 4.4 2 8.6 4.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) FAM176 PF14851.6 KXT00027.1 - 0.47 10.1 0.0 0.47 10.1 0.0 2.9 3 1 0 3 3 3 0 FAM176 family DUF383 PF04063.14 KXT00028.1 - 2e-67 226.6 0.0 2.2e-66 223.1 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.13 KXT00028.1 - 2.4e-21 75.3 0.0 5.9e-21 74.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF384) Glyco_hydro_43 PF04616.14 KXT00029.1 - 6.9e-40 137.2 5.5 8e-40 136.9 5.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF1338 PF07063.13 KXT00030.1 - 2.1e-111 372.2 0.0 2.4e-111 372.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) ATPase PF06745.13 KXT00030.1 - 0.18 11.1 0.1 1.2 8.4 0.0 2.0 2 0 0 2 2 2 0 KaiC HpcH_HpaI PF03328.14 KXT00031.1 - 0.1 11.7 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family HpcH_HpaI PF03328.14 KXT00032.1 - 0.1 11.7 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family MFS_1 PF07690.16 KXT00034.1 - 2.8e-23 82.4 63.1 3e-16 59.3 25.5 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Toxin_32 PF08120.11 KXT00036.1 - 0.045 13.6 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 Tamulustoxin family Pterin_4a PF01329.19 KXT00038.1 - 2.3e-26 91.8 0.7 3.6e-26 91.2 0.7 1.3 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase BKACE PF05853.12 KXT00038.1 - 0.089 12.1 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme Homoserine_dh PF00742.19 KXT00039.1 - 7.6e-51 172.5 0.0 9.9e-51 172.1 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 KXT00039.1 - 1.2e-14 54.9 0.0 2.2e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain TPP_enzyme_N PF02776.18 KXT00041.1 - 1.1e-53 181.3 0.1 3.3e-53 179.8 0.1 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KXT00041.1 - 1.2e-44 151.8 0.1 2.3e-43 147.6 0.0 2.6 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KXT00041.1 - 1.4e-39 134.9 0.4 3.3e-39 133.8 0.2 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 KXT00041.1 - 0.0013 18.5 0.6 0.0041 16.9 0.0 2.1 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg ORC6 PF05460.13 KXT00041.1 - 5.7 6.1 10.3 9.6 5.4 10.3 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Transket_pyr PF02779.24 KXT00042.1 - 4.9e-49 166.4 0.0 8.7e-49 165.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KXT00042.1 - 2.9e-35 120.9 0.3 1e-34 119.1 0.0 2.1 3 0 0 3 3 3 1 Transketolase, C-terminal domain Fungal_trans PF04082.18 KXT00043.1 - 7e-12 44.9 0.8 1.2e-11 44.2 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT00043.1 - 2.4e-05 24.4 12.3 6.4e-05 23.0 12.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXT00044.1 - 7e-12 44.9 0.8 1.2e-11 44.2 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT00044.1 - 2.4e-05 24.4 12.3 6.4e-05 23.0 12.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXT00045.1 - 7e-12 44.9 0.8 1.2e-11 44.2 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT00045.1 - 2.4e-05 24.4 12.3 6.4e-05 23.0 12.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BTB PF00651.31 KXT00046.1 - 0.0029 17.8 0.0 0.024 14.9 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain Cation_efflux PF01545.21 KXT00047.1 - 1.1e-09 38.3 15.2 1.6e-09 37.8 15.2 1.2 1 0 0 1 1 1 1 Cation efflux family SWIRM-assoc_2 PF16496.5 KXT00048.1 - 0.2 10.5 4.0 0.37 9.6 4.0 1.4 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal TPR_19 PF14559.6 KXT00049.1 - 0.0001 22.7 2.1 0.48 11.0 0.1 3.2 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXT00049.1 - 0.054 14.1 8.2 1.5 9.5 0.5 4.3 2 1 2 4 4 4 0 Tetratricopeptide repeat PerC PF06069.11 KXT00049.1 - 0.084 13.1 0.0 0.28 11.5 0.0 1.8 1 0 0 1 1 1 0 PerC transcriptional activator UL42 PF17638.2 KXT00049.1 - 0.48 10.4 3.9 0.94 9.5 3.9 1.4 1 0 0 1 1 1 0 HCMV UL42 DIOX_N PF14226.6 KXT00050.1 - 1.2e-30 106.7 0.0 1.8e-30 106.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXT00050.1 - 7.6e-20 71.3 0.0 1.3e-19 70.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NmrA PF05368.13 KXT00051.1 - 2.2e-11 43.8 0.0 2.9e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXT00051.1 - 8.1e-09 35.6 0.0 1.8e-08 34.5 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Na_Ca_ex PF01699.24 KXT00060.1 - 6.1e-49 165.8 46.8 9.3e-28 97.1 17.3 2.9 3 0 0 3 3 3 2 Sodium/calcium exchanger protein MARVEL PF01284.23 KXT00060.1 - 0.0097 15.9 0.8 0.0097 15.9 0.8 4.6 4 2 2 6 6 6 2 Membrane-associating domain Peptidase_C48 PF02902.19 KXT00061.1 - 7.4e-17 61.9 0.1 2.2e-16 60.4 0.1 1.8 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF4951 PF16309.5 KXT00061.1 - 0.099 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Domian of unknown function (DUF4951) Acetyltransf_7 PF13508.7 KXT00062.1 - 8.8e-06 26.1 0.1 1.5e-05 25.4 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXT00062.1 - 0.00046 20.1 0.0 0.0017 18.3 0.0 1.8 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 KXT00062.1 - 0.00088 19.5 0.0 0.0015 18.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXT00062.1 - 0.046 13.7 0.0 0.077 12.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Peptidase_C48 PF02902.19 KXT00063.1 - 6.3e-17 62.1 0.1 2e-16 60.5 0.1 1.8 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF4951 PF16309.5 KXT00063.1 - 0.09 12.8 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Domian of unknown function (DUF4951) Peptidase_C48 PF02902.19 KXT00064.1 - 6.3e-17 62.1 0.1 2e-16 60.5 0.1 1.8 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF4951 PF16309.5 KXT00064.1 - 0.09 12.8 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Domian of unknown function (DUF4951) PMM PF03332.13 KXT00065.1 - 9.1e-101 336.2 0.1 1.1e-100 336.0 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 KXT00065.1 - 0.0002 21.2 0.0 0.0019 18.0 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KXT00065.1 - 0.065 13.6 0.0 7.1 7.0 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase HsbA PF12296.8 KXT00066.1 - 6.8e-26 91.0 4.0 8.8e-26 90.7 4.0 1.1 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Phage_CP76 PF06892.11 KXT00066.1 - 0.015 14.8 0.2 0.29 10.6 0.1 2.5 2 1 1 3 3 3 0 Phage regulatory protein CII (CP76) DUF2892 PF11127.8 KXT00066.1 - 0.26 11.4 1.4 0.29 11.2 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) PAPA-1 PF04795.12 KXT00069.1 - 2.4e-28 98.8 5.8 2.4e-28 98.8 5.8 3.6 3 0 0 3 3 3 1 PAPA-1-like conserved region DUF4756 PF15948.5 KXT00069.1 - 0.087 12.7 6.3 0.15 11.9 6.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4756) PAPA-1 PF04795.12 KXT00070.1 - 2.2e-28 98.8 5.8 2.2e-28 98.8 5.8 3.7 3 0 0 3 3 3 1 PAPA-1-like conserved region DUF4756 PF15948.5 KXT00070.1 - 0.088 12.7 6.3 0.14 12.0 6.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4756) DNA_pol_A_exo1 PF01612.20 KXT00071.1 - 1.4e-18 67.2 0.1 4.2e-18 65.7 0.0 1.9 2 0 0 2 2 2 1 3'-5' exonuclease Baculo_PEP_C PF04513.12 KXT00071.1 - 1 9.4 13.5 1.4 8.9 4.0 3.5 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sugar_tr PF00083.24 KXT00072.1 - 7.5e-68 229.4 28.6 1.7e-66 225.0 28.6 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXT00072.1 - 3.1e-14 52.7 39.4 2.4e-11 43.1 12.5 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_19 PF14559.6 KXT00072.1 - 0.096 13.2 0.5 0.21 12.1 0.5 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TFIIF_alpha PF05793.12 KXT00073.1 - 0.39 9.2 8.4 0.59 8.7 8.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) NOA36 PF06524.12 KXT00073.1 - 4 6.7 8.3 7.2 5.8 8.3 1.3 1 0 0 1 1 1 0 NOA36 protein PPP4R2 PF09184.11 KXT00073.1 - 4.5 6.8 6.2 6.8 6.2 6.2 1.1 1 0 0 1 1 1 0 PPP4R2 Cwf_Cwc_15 PF04889.12 KXT00073.1 - 5.9 6.5 12.8 8.7 6.0 12.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein MCM PF00493.23 KXT00074.1 - 2.8e-102 340.6 0.0 4.4e-102 339.9 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KXT00074.1 - 1.3e-33 115.5 0.3 2.3e-33 114.7 0.3 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KXT00074.1 - 2.5e-17 63.1 0.1 6.4e-17 61.8 0.1 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KXT00074.1 - 1e-16 61.4 0.3 2.5e-16 60.2 0.3 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KXT00074.1 - 1.5e-06 27.7 0.0 0.00013 21.4 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KXT00074.1 - 4.3e-06 26.8 0.0 1.3e-05 25.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 KXT00074.1 - 0.012 15.4 0.0 0.046 13.6 0.0 2.0 2 0 0 2 2 2 0 AAA lid domain DUF5319 PF17252.2 KXT00074.1 - 0.038 14.2 0.0 0.091 13.0 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5319) Sigma54_activat PF00158.26 KXT00074.1 - 0.062 13.0 0.0 0.41 10.3 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_3 PF07726.11 KXT00074.1 - 0.072 13.0 0.1 0.25 11.2 0.1 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) zf-C2HC5 PF06221.13 KXT00075.1 - 0.071 13.1 0.8 0.17 11.9 0.8 1.6 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type GNAT_C PF18164.1 KXT00075.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 GNAT-like C-terminal domain E1-E2_ATPase PF00122.20 KXT00076.1 - 1.1e-52 178.2 6.0 7.4e-52 175.5 1.7 2.7 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KXT00076.1 - 1.5e-46 158.4 5.2 1.5e-46 158.4 5.2 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KXT00076.1 - 1.2e-23 84.6 3.2 1.1e-22 81.3 3.2 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXT00076.1 - 3e-20 72.1 0.1 6.1e-20 71.1 0.1 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KXT00076.1 - 9.6e-20 70.0 0.0 2.9e-19 68.5 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KXT00076.1 - 4.7e-10 39.6 1.1 1.8e-06 27.9 1.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 KXT00076.1 - 7.6e-07 29.7 0.1 4.2e-06 27.3 0.0 2.3 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase DUF2463 PF09591.10 KXT00076.1 - 0.13 12.1 6.7 0.051 13.4 2.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2463) bZIP_2 PF07716.15 KXT00077.1 - 0.0065 16.5 10.4 0.017 15.2 10.4 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KXT00077.1 - 0.024 14.7 7.7 0.047 13.8 7.7 1.5 1 0 0 1 1 1 0 bZIP transcription factor SR-25 PF10500.9 KXT00077.1 - 0.15 11.7 10.5 0.018 14.6 5.8 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Polyketide_cyc PF03364.20 KXT00078.1 - 7.4e-18 65.0 0.0 1.2e-17 64.3 0.0 1.4 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Big_5 PF13205.6 KXT00078.1 - 0.0032 18.2 0.6 0.067 13.9 0.1 2.7 3 0 0 3 3 3 1 Bacterial Ig-like domain Polyketide_cyc2 PF10604.9 KXT00078.1 - 0.0049 17.1 0.0 1.9 8.7 0.0 2.3 1 1 1 2 2 2 2 Polyketide cyclase / dehydrase and lipid transport CMAS PF02353.20 KXT00079.1 - 7.5e-60 202.5 0.0 9.5e-60 202.2 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 KXT00079.1 - 4.4e-09 36.9 0.0 8.7e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXT00079.1 - 3.1e-08 33.6 0.0 4.8e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXT00079.1 - 4.6e-08 33.7 0.0 1.4e-07 32.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXT00079.1 - 0.0055 17.4 0.0 0.011 16.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KXT00079.1 - 0.038 13.7 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KXT00079.1 - 0.12 11.9 0.1 0.21 11.1 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain NMO PF03060.15 KXT00080.1 - 5.4e-54 183.8 0.6 8e-54 183.2 0.6 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KXT00080.1 - 7.6e-10 38.3 1.0 1.1e-09 37.8 1.0 1.2 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KXT00080.1 - 0.013 14.6 3.8 0.023 13.7 3.8 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase PEP_hydrolase PF09370.10 KXT00080.1 - 0.031 13.5 0.0 0.05 12.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate hydrolase-like DUF3173 PF11372.8 KXT00080.1 - 0.092 12.6 0.1 0.25 11.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3173) SHR3_chaperone PF08229.11 KXT00081.1 - 6.8e-77 256.7 0.0 7.6e-77 256.5 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 DUF5453 PF17534.2 KXT00081.1 - 0.96 9.4 5.5 0.19 11.6 0.9 2.0 2 1 0 3 3 3 0 Family of unknown function (DUF5453) Glyco_hydro_32N PF00251.20 KXT00082.1 - 6.6e-43 147.4 0.0 1.1e-42 146.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KXT00082.1 - 4.2e-27 95.1 0.0 6.6e-27 94.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal DUF4975 PF16346.5 KXT00082.1 - 5.1e-05 23.4 0.0 0.0001 22.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4975) Rad60-SLD PF11976.8 KXT00084.1 - 0.0029 17.4 0.0 0.0072 16.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KXT00084.1 - 0.14 12.0 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin family MutS_V PF00488.21 KXT00085.1 - 5.7e-63 212.4 1.0 1e-62 211.5 1.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KXT00085.1 - 1.1e-33 117.1 0.8 4.2e-33 115.2 0.8 2.1 1 1 0 1 1 1 1 MutS domain III MutS_II PF05188.17 KXT00085.1 - 1e-08 35.5 0.0 2.8e-08 34.1 0.0 1.8 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 KXT00085.1 - 8.6e-05 22.8 1.5 0.00015 22.0 0.1 2.2 2 0 0 2 2 2 1 MutS family domain IV AAA_30 PF13604.6 KXT00085.1 - 0.018 14.8 0.1 0.059 13.1 0.1 1.9 1 0 0 1 1 1 0 AAA domain AAA_27 PF13514.6 KXT00085.1 - 0.051 13.2 0.2 1 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain BAR_3_WASP_bdg PF10456.9 KXT00085.1 - 0.073 12.5 0.1 0.38 10.2 0.0 2.2 2 0 0 2 2 2 0 WASP-binding domain of Sorting nexin protein LSM PF01423.22 KXT00086.1 - 3.7e-22 77.8 0.0 4.1e-22 77.6 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KXT00086.1 - 0.056 13.6 0.0 0.063 13.4 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain HET PF06985.11 KXT00089.1 - 3.5e-11 43.7 3.2 1.1e-07 32.3 0.3 2.8 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF3602 PF12223.8 KXT00090.1 - 2e-16 60.4 9.9 1.6e-15 57.4 2.7 3.1 2 2 1 3 3 3 2 Protein of unknown function (DUF3602) zf-H2C2_2 PF13465.6 KXT00092.1 - 1.3e-13 50.7 16.2 1.1e-07 31.9 2.2 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KXT00092.1 - 8.2e-09 35.4 23.8 0.012 16.0 3.8 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXT00092.1 - 7e-06 26.5 20.7 0.095 13.6 5.6 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KXT00092.1 - 0.00011 22.1 18.1 0.006 16.6 0.1 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-Di19 PF05605.12 KXT00092.1 - 0.0068 16.7 6.1 0.014 15.6 6.1 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding Tup_N PF08581.10 KXT00092.1 - 0.013 15.7 0.1 0.027 14.8 0.1 1.5 1 0 0 1 1 1 0 Tup N-terminal zf-C2H2_8 PF15909.5 KXT00092.1 - 0.11 12.8 7.3 0.75 10.1 1.3 2.5 1 1 1 2 2 2 0 C2H2-type zinc ribbon DUF2383 PF09537.10 KXT00092.1 - 0.11 12.8 0.1 0.3 11.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) zf-C2H2_jaz PF12171.8 KXT00092.1 - 0.13 12.6 7.7 2.2 8.7 1.8 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DUF3268 PF11672.8 KXT00092.1 - 0.16 12.3 1.3 0.3 11.4 0.5 1.9 1 1 0 1 1 1 0 zinc-finger-containing domain Zn-ribbon_8 PF09723.10 KXT00092.1 - 0.24 11.5 6.6 0.25 11.5 2.1 2.6 2 1 0 2 2 2 0 Zinc ribbon domain DZR PF12773.7 KXT00092.1 - 0.72 9.9 8.4 5.1 7.2 8.2 2.2 1 1 1 2 2 2 0 Double zinc ribbon GAGA PF09237.11 KXT00092.1 - 0.86 9.5 7.5 0.51 10.2 1.5 2.9 1 1 1 2 2 2 0 GAGA factor Rad50_zn_hook PF04423.14 KXT00092.1 - 0.87 9.5 2.6 0.6 10.0 0.3 1.9 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-C2H2_9 PF16293.5 KXT00092.1 - 1.2 9.0 2.7 6.7 6.6 0.2 2.8 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-C2HC_2 PF13913.6 KXT00092.1 - 1.3 9.0 6.1 0.32 10.9 0.6 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-CHCC PF10276.9 KXT00092.1 - 7 6.8 8.4 8 6.6 0.4 3.0 3 0 0 3 3 3 0 Zinc-finger domain AICARFT_IMPCHas PF01808.18 KXT00093.1 - 3.5e-90 302.5 0.0 4.6e-90 302.1 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 KXT00093.1 - 1.8e-21 76.1 0.0 3.7e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain COesterase PF00135.28 KXT00094.1 - 4.9e-71 240.1 0.0 9e-71 239.3 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXT00094.1 - 4.7e-08 33.2 0.0 2.1e-07 31.0 0.0 1.9 2 1 0 2 2 2 1 alpha/beta hydrolase fold Diphthami_syn_2 PF01902.17 KXT00095.1 - 5.9e-20 71.7 0.0 1.9e-19 70.1 0.0 1.7 1 1 0 1 1 1 1 Diphthamide synthase Ribonuc_L-PSP PF01042.21 KXT00095.1 - 2.7e-10 40.3 0.0 1.7e-06 28.0 0.0 2.5 2 0 0 2 2 2 2 Endoribonuclease L-PSP FMO-like PF00743.19 KXT00096.1 - 3.2e-19 68.7 0.1 1.7e-15 56.5 0.1 2.6 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KXT00096.1 - 2.1e-11 43.9 0.0 2.9e-10 40.2 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KXT00096.1 - 3.6e-08 32.9 0.1 5.3e-06 25.8 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KXT00096.1 - 2.4e-07 30.3 0.0 0.0028 16.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXT00096.1 - 3.4e-05 23.3 0.1 0.0047 16.2 0.0 3.2 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXT00096.1 - 0.0019 17.8 0.1 1.6 8.2 0.0 3.1 2 1 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXT00096.1 - 0.0051 16.8 0.0 0.15 12.1 0.0 2.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 KXT00096.1 - 0.058 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Shikimate_DH PF01488.20 KXT00096.1 - 0.085 12.9 0.0 0.91 9.6 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase LBR_tudor PF09465.10 KXT00096.1 - 0.18 11.6 0.5 0.59 10.0 0.2 2.0 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain WD40 PF00400.32 KXT00097.1 - 2.6e-20 72.3 31.5 9.2e-05 23.1 1.6 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat NLE PF08154.12 KXT00097.1 - 2.3e-18 66.5 0.3 5.2e-18 65.3 0.2 1.7 2 0 0 2 2 2 1 NLE (NUC135) domain Nup160 PF11715.8 KXT00097.1 - 0.0003 19.6 5.0 0.034 12.8 0.5 2.9 2 1 0 3 3 3 2 Nucleoporin Nup120/160 Alpha-amylase PF00128.24 KXT00098.1 - 7.4e-09 35.6 0.0 7.4e-09 35.6 0.0 1.0 1 0 0 1 1 1 1 Alpha amylase, catalytic domain RXT2_N PF08595.11 KXT00099.1 - 0.1 12.6 0.1 0.1 12.6 0.1 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal PRELI PF04707.14 KXT00099.1 - 0.12 12.2 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 PRELI-like family Glyco_hydro_79C PF16862.5 KXT00100.1 - 7.9e-20 71.7 0.0 1.7e-19 70.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Glyco_hydro_79n PF03662.14 KXT00100.1 - 0.067 12.1 0.0 0.37 9.7 0.0 2.1 2 1 0 2 2 2 0 Glycosyl hydrolase family 79, N-terminal domain CHCH PF06747.13 KXT00101.1 - 0.00078 19.5 3.7 0.0018 18.3 3.3 1.8 1 1 1 2 2 2 1 CHCH domain COX6B PF02297.17 KXT00101.1 - 0.0041 17.3 4.6 0.0056 16.9 4.6 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb MTCP1 PF08991.10 KXT00101.1 - 0.011 15.9 2.1 0.014 15.6 2.1 1.2 1 0 0 1 1 1 0 Mature-T-Cell Proliferation I type Cnd2 PF05786.14 KXT00102.1 - 8.7e-298 990.3 4.0 1.1e-297 990.0 4.0 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 KXT00102.1 - 0.035 14.3 0.0 0.11 12.8 0.0 1.8 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal INSIG PF07281.12 KXT00106.1 - 2.6e-73 246.2 0.1 3.3e-73 245.8 0.1 1.1 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) Glyco_hydro_72 PF03198.14 KXT00107.1 - 2.7e-103 345.6 0.0 4.7e-103 344.7 0.1 1.3 2 0 0 2 2 2 1 Glucanosyltransferase Cellulase PF00150.18 KXT00107.1 - 0.0008 18.9 0.1 0.0016 17.9 0.1 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 KXT00107.1 - 0.052 12.6 0.1 0.15 11.1 0.1 1.6 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain MOSC PF03473.17 KXT00108.1 - 1.5e-32 112.4 0.0 3.1e-32 111.3 0.0 1.6 1 0 0 1 1 1 1 MOSC domain Aminotran_5 PF00266.19 KXT00108.1 - 9.8e-25 87.3 0.0 2.7e-24 85.8 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V MOSC_N PF03476.16 KXT00108.1 - 1.4e-23 83.1 0.0 2.7e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain DUF1640 PF07798.11 KXT00109.1 - 4e-58 196.3 10.5 4.9e-58 196.0 10.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) GNAT_acetyltr_2 PF13718.6 KXT00109.1 - 0.14 11.6 1.6 0.46 9.9 0.0 2.0 1 1 1 2 2 2 0 GNAT acetyltransferase 2 XhlA PF10779.9 KXT00109.1 - 0.55 10.5 3.9 0.21 11.8 0.3 2.2 3 0 0 3 3 3 0 Haemolysin XhlA Uds1 PF15456.6 KXT00120.1 - 6.1e-36 123.5 9.8 6.1e-36 123.5 9.8 6.4 5 2 1 6 6 6 2 Up-regulated During Septation HR1 PF02185.16 KXT00120.1 - 0.00015 21.8 2.6 0.00015 21.8 2.6 8.4 8 2 0 8 8 8 2 Hr1 repeat zf-RING_6 PF14835.6 KXT00121.1 - 0.0042 16.9 7.2 0.0075 16.1 7.2 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.6 KXT00121.1 - 0.21 11.5 9.4 0.33 10.8 9.4 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXT00121.1 - 1.1 9.2 11.5 1.9 8.4 11.5 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Pex26 PF07163.12 KXT00122.1 - 0.028 13.8 9.5 0.28 10.5 1.6 2.8 3 0 0 3 3 3 0 Pex26 protein CDC45 PF02724.14 KXT00122.1 - 0.037 12.3 8.3 0.038 12.3 6.8 1.7 2 0 0 2 2 2 0 CDC45-like protein Merozoite_SPAM PF07133.11 KXT00122.1 - 0.072 13.1 9.7 0.11 12.5 9.7 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Plasmodium_Vir PF05795.11 KXT00122.1 - 0.14 11.5 0.6 0.22 10.9 0.6 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Radial_spoke_3 PF06098.11 KXT00122.1 - 0.16 11.2 13.9 0.28 10.4 13.9 1.5 1 0 0 1 1 1 0 Radial spoke protein 3 RR_TM4-6 PF06459.12 KXT00122.1 - 0.92 9.3 10.0 1.5 8.6 10.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Borrelia_P83 PF05262.11 KXT00122.1 - 1.2 7.5 10.6 1.8 7.0 10.6 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Presenilin PF01080.17 KXT00122.1 - 1.6 7.5 7.3 2.7 6.7 7.3 1.4 1 0 0 1 1 1 0 Presenilin MSA-2c PF12238.8 KXT00122.1 - 2.2 8.2 8.9 0.81 9.7 0.8 2.3 2 0 0 2 2 2 0 Merozoite surface antigen 2c Velvet PF11754.8 KXT00123.1 - 2e-33 116.4 5.7 3.9e-26 92.5 0.4 3.2 2 2 1 3 3 3 2 Velvet factor Imm59 PF15597.6 KXT00123.1 - 0.17 12.4 0.0 0.45 11.0 0.0 1.7 1 0 0 1 1 1 0 Immunity protein 59 Isy1 PF06246.12 KXT00124.1 - 2.7e-88 295.8 1.9 3.5e-88 295.5 1.9 1.1 1 0 0 1 1 1 1 Isy1-like splicing family YolD PF08863.10 KXT00124.1 - 0.024 14.7 0.1 0.057 13.5 0.1 1.6 1 0 0 1 1 1 0 YolD-like protein MFS_1 PF07690.16 KXT00125.1 - 3.8e-34 118.2 34.5 3.8e-34 118.2 34.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 KXT00125.1 - 0.083 12.7 2.6 0.17 11.7 2.6 1.5 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) LapA_dom PF06305.11 KXT00125.1 - 0.4 10.5 0.1 0.4 10.5 0.1 3.7 3 1 1 4 4 4 0 Lipopolysaccharide assembly protein A domain Fungal_trans PF04082.18 KXT00127.1 - 0.00067 18.8 0.0 0.0013 17.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain McrBC PF10117.9 KXT00132.1 - 0.048 12.8 0.0 0.054 12.6 0.0 1.0 1 0 0 1 1 1 0 McrBC 5-methylcytosine restriction system component F-box-like PF12937.7 KXT00133.1 - 0.012 15.5 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 KXT00133.1 - 0.055 13.4 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 F-box domain Bac_rhamnosid6H PF17389.2 KXT00134.1 - 4.8e-117 391.0 0.0 6.4e-117 390.6 0.0 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 KXT00134.1 - 4.3e-41 140.6 0.0 9.5e-41 139.5 0.0 1.6 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 KXT00134.1 - 1e-28 99.3 0.0 1.9e-28 98.4 0.0 1.5 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 KXT00134.1 - 8.1e-17 60.8 0.1 2.9e-16 59.0 0.1 2.0 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain PNP_UDP_1 PF01048.20 KXT00135.1 - 8.2e-15 54.7 0.1 1.4e-14 53.9 0.1 1.5 1 1 0 1 1 1 1 Phosphorylase superfamily MWFE PF15879.5 KXT00136.1 - 1.7e-23 82.5 0.5 2.4e-23 82.1 0.5 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit LPD26 PF18842.1 KXT00136.1 - 0.059 13.4 0.0 0.091 12.7 0.0 1.2 1 0 0 1 1 1 0 Large polyvalent protein associated domain 26 CN_hydrolase PF00795.22 KXT00138.1 - 1.4e-32 113.0 0.0 1.2e-31 110.0 0.0 2.0 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase CN_hydrolase PF00795.22 KXT00139.1 - 1.4e-32 113.0 0.0 1.2e-31 110.0 0.0 2.0 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Ufd2P_core PF10408.9 KXT00140.1 - 2.5e-206 687.1 6.4 3.1e-206 686.8 6.4 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 KXT00140.1 - 1.5e-27 95.5 1.2 4.9e-27 93.9 1.2 2.0 1 0 0 1 1 1 1 U-box domain CTP_transf_like PF01467.26 KXT00140.1 - 0.076 13.2 0.1 2.6 8.2 0.0 3.5 2 1 0 2 2 2 0 Cytidylyltransferase-like Ndc1_Nup PF09531.10 KXT00140.1 - 0.39 9.3 5.1 0.67 8.6 5.1 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Cation_ATPase_C PF00689.21 KXT00141.1 - 2.9e-37 128.1 6.4 2.9e-37 128.1 6.4 3.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KXT00141.1 - 5.6e-37 127.0 0.3 5.6e-37 127.0 0.3 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KXT00141.1 - 2.7e-22 80.1 0.1 1.1e-11 45.4 0.0 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXT00141.1 - 2.9e-18 65.7 0.0 5.9e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KXT00141.1 - 5.6e-09 35.6 0.0 2.6e-08 33.4 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KXT00141.1 - 0.00012 22.0 0.0 0.00023 21.0 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KXT00141.1 - 0.026 14.9 0.0 0.13 12.6 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF2231 PF09990.9 KXT00141.1 - 0.026 14.9 1.1 0.026 14.9 1.1 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) TMEM43 PF07787.12 KXT00141.1 - 1.2 8.5 6.1 0.42 10.0 0.3 2.5 2 0 0 2 2 2 0 Transmembrane protein 43 PGG PF13962.6 KXT00141.1 - 9.7 6.1 8.2 0.62 9.9 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF1667 PF07892.11 KXT00142.1 - 0.12 12.4 0.0 0.33 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1667) Cofilin_ADF PF00241.20 KXT00143.1 - 1.5e-33 115.2 0.0 1.1e-15 57.4 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein TatD_DNase PF01026.21 KXT00145.1 - 1.6e-55 188.2 0.0 2.1e-55 187.9 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase BRCA-2_OB1 PF09103.10 KXT00145.1 - 0.098 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 AP_endonuc_2 PF01261.24 KXT00145.1 - 0.11 11.9 0.3 0.68 9.3 0.1 2.3 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel SHD1 PF03983.12 KXT00146.1 - 0.00048 19.9 0.2 0.14 12.0 0.0 3.1 3 1 0 3 3 3 2 SLA1 homology domain 1, SHD1 RNase_PH_C PF03725.15 KXT00146.1 - 0.054 13.5 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Calici_PP_N PF08405.11 KXT00146.1 - 0.16 10.8 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Viral polyprotein N-terminal Glyoxalase PF00903.25 KXT00147.1 - 1.9e-10 41.0 0.0 4.2e-10 39.9 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KXT00147.1 - 0.049 13.9 0.0 0.13 12.6 0.0 1.7 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Ribosomal_S7 PF00177.21 KXT00148.1 - 4e-30 104.4 0.0 8.8e-30 103.3 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein S7p/S5e Meth_synt_2 PF01717.18 KXT00149.1 - 1.1e-152 508.0 0.0 9.7e-148 491.7 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KXT00149.1 - 4.1e-122 407.6 0.3 1.6e-115 385.9 0.1 3.0 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.17 KXT00149.1 - 2.9e-05 23.4 0.1 0.0033 16.6 0.0 2.9 3 0 0 3 3 3 2 Uroporphyrinogen decarboxylase (URO-D) SHOCT PF09851.9 KXT00149.1 - 0.21 11.4 2.3 0.47 10.3 0.1 2.9 3 0 0 3 3 3 0 Short C-terminal domain Abhydrolase_3 PF07859.13 KXT00150.1 - 5.3e-24 85.3 0.0 7.5e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXT00150.1 - 4.6e-22 78.4 0.0 5.6e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 KXT00150.1 - 0.0071 15.3 0.1 0.13 11.1 0.0 2.1 2 0 0 2 2 2 1 Carboxylesterase family DUF3273 PF11677.8 KXT00151.1 - 0.0042 16.4 0.0 0.0063 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) AMP-binding PF00501.28 KXT00153.1 - 6.2e-85 285.3 0.0 7.9e-85 285.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXT00153.1 - 7.7e-16 58.8 0.3 1.6e-15 57.8 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain RTX_C PF08339.10 KXT00153.1 - 0.069 13.2 0.1 0.55 10.3 0.0 2.2 2 0 0 2 2 2 0 RTX C-terminal domain Mito_carr PF00153.27 KXT00154.1 - 1.2e-68 227.1 0.6 1.1e-22 79.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Sulfatase PF00884.23 KXT00155.1 - 7.6e-48 163.5 0.0 8.3e-46 156.8 0.0 2.0 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KXT00155.1 - 7.8e-08 32.3 2.8 0.0048 16.5 0.8 2.3 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1501 PF07394.12 KXT00155.1 - 0.0075 15.4 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) DUF4965 PF16335.5 KXT00156.1 - 2.8e-66 222.5 0.1 7.2e-66 221.1 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF5127 PF17168.4 KXT00156.1 - 6.1e-46 157.0 1.5 6.1e-46 157.0 1.5 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF5127) DUF1793 PF08760.11 KXT00156.1 - 4.1e-42 144.5 0.7 4.1e-42 144.5 0.7 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KXT00156.1 - 2.6e-06 26.9 0.0 6e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) Glyco_hydr_116N PF12215.8 KXT00156.1 - 0.00021 20.9 0.2 0.00037 20.1 0.2 1.3 1 0 0 1 1 1 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term VASt PF16016.5 KXT00157.1 - 1.7e-36 125.9 0.0 2.5e-36 125.4 0.0 1.3 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 KXT00157.1 - 9.2e-23 80.3 0.0 1.8e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 GRAM domain Methyltransf_11 PF08241.12 KXT00158.1 - 1.2e-13 51.5 0.0 3.6e-13 50.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXT00158.1 - 1.8e-13 51.0 0.0 3.5e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXT00158.1 - 3.1e-12 47.1 0.0 5.4e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXT00158.1 - 4.9e-11 42.6 0.0 7.5e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXT00158.1 - 0.0003 20.2 0.0 0.00054 19.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KXT00158.1 - 0.0021 17.9 0.0 0.0031 17.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 KXT00158.1 - 0.0095 15.6 0.0 0.023 14.3 0.0 1.5 2 0 0 2 2 2 1 Nodulation protein S (NodS) DUF938 PF06080.12 KXT00158.1 - 0.099 12.4 0.0 0.2 11.4 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF938) MethyltransfD12 PF02086.15 KXT00158.1 - 0.14 11.8 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase ICE2 PF08426.10 KXT00159.1 - 1.3e-146 488.9 0.7 1.5e-146 488.7 0.7 1.0 1 0 0 1 1 1 1 ICE2 adh_short PF00106.25 KXT00161.1 - 3.6e-35 121.2 2.4 5e-27 94.6 0.0 2.3 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXT00161.1 - 1.8e-34 119.4 1.8 2.6e-32 112.3 1.8 2.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT00161.1 - 2.4e-10 40.6 0.3 4.5e-09 36.5 0.0 2.2 2 0 0 2 2 2 1 KR domain ADH_zinc_N PF00107.26 KXT00161.1 - 0.041 13.9 0.1 0.079 12.9 0.1 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase DUF1776 PF08643.10 KXT00161.1 - 0.098 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) AIF_C PF14721.6 KXT00161.1 - 0.12 12.7 0.5 1.3 9.4 0.0 2.3 2 1 1 3 3 3 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Lactonase PF10282.9 KXT00162.1 - 1.3e-27 97.0 0.0 2.8e-27 95.9 0.0 1.5 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SGL PF08450.12 KXT00162.1 - 0.0075 15.9 0.0 0.055 13.0 0.0 2.3 3 0 0 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 KXT00162.1 - 0.13 12.5 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Arylesterase CR6_interact PF10147.9 KXT00163.1 - 0.2 11.4 0.3 0.32 10.7 0.3 1.3 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 MOZ_SAS PF01853.18 KXT00164.1 - 1.4e-65 220.3 0.0 4.5e-32 111.2 0.0 2.2 2 0 0 2 2 2 2 MOZ/SAS family zf-MYST PF17772.1 KXT00164.1 - 1.7e-19 69.1 5.3 3.5e-19 68.1 5.3 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain PHD_4 PF16866.5 KXT00164.1 - 1.4e-10 41.1 8.3 1.5e-10 41.0 6.2 2.1 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 KXT00164.1 - 0.0031 17.4 7.5 0.0031 17.4 7.5 2.3 2 0 0 2 2 2 1 PHD-finger C1_1 PF00130.22 KXT00164.1 - 0.0033 17.3 0.6 0.011 15.6 0.6 1.9 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) ANT PF03374.14 KXT00164.1 - 0.02 15.2 0.0 0.048 14.0 0.0 1.6 1 0 0 1 1 1 0 Phage antirepressor protein KilAC domain Prok-RING_1 PF14446.6 KXT00164.1 - 0.063 13.2 1.6 0.18 11.8 1.6 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 IF2_N PF04760.15 KXT00164.1 - 0.1 12.4 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region PHD_2 PF13831.6 KXT00164.1 - 4 7.1 7.3 0.32 10.6 1.6 2.1 2 0 0 2 2 2 0 PHD-finger CAF1 PF04857.20 KXT00165.1 - 5.2e-82 275.6 0.0 6.3e-82 275.3 0.0 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease PP-binding PF00550.25 KXT00165.1 - 0.16 12.4 0.0 0.47 10.8 0.0 1.8 2 0 0 2 2 2 0 Phosphopantetheine attachment site DASH_Dad4 PF08650.10 KXT00184.1 - 5.7e-31 106.3 4.3 6.3e-31 106.2 4.3 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 GM_CSF PF01109.17 KXT00184.1 - 0.017 15.3 0.3 0.019 15.1 0.3 1.1 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor BPL_N PF09825.9 KXT00185.1 - 1.9e-139 465.0 0.0 2.7e-139 464.4 0.0 1.2 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 KXT00185.1 - 1.1e-22 80.3 0.1 1.8e-22 79.6 0.1 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 KXT00185.1 - 2.3e-05 24.2 0.2 5.6e-05 22.9 0.2 1.7 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain Glyco_hydro_42M PF08532.10 KXT00185.1 - 0.021 14.3 0.8 0.9 9.0 0.0 2.8 3 0 0 3 3 3 0 Beta-galactosidase trimerisation domain GATase_3 PF07685.14 KXT00185.1 - 0.18 11.4 0.1 0.32 10.6 0.1 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain adh_short_C2 PF13561.6 KXT00186.1 - 7.7e-52 176.2 2.9 1.9e-50 171.6 2.9 2.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXT00186.1 - 9e-37 126.4 5.2 6.8e-36 123.6 5.2 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXT00186.1 - 7.3e-08 32.5 0.7 7.3e-08 32.5 0.7 2.0 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KXT00186.1 - 0.00031 20.3 0.1 0.0017 17.8 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF448 PF04296.13 KXT00186.1 - 0.025 14.5 0.0 0.2 11.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF448) PWWP PF00855.17 KXT00187.1 - 0.018 15.4 0.1 0.079 13.4 0.1 2.2 1 1 0 1 1 1 0 PWWP domain PWWP PF00855.17 KXT00188.1 - 0.017 15.5 0.1 0.077 13.4 0.1 2.2 1 1 0 1 1 1 0 PWWP domain ADH_zinc_N PF00107.26 KXT00189.1 - 1.5e-20 73.4 0.0 4.3e-20 72.0 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXT00189.1 - 0.032 14.1 0.2 0.17 11.8 0.0 2.3 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain Methyltransf_5 PF01795.19 KXT00190.1 - 0.029 13.9 0.0 0.03 13.8 0.0 1.0 1 0 0 1 1 1 0 MraW methylase family DUF2458 PF10454.9 KXT00192.1 - 1.1e-57 194.5 0.3 1.3e-57 194.2 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) Not1 PF04054.15 KXT00194.1 - 1.2e-111 373.2 0.3 2.8e-111 372.0 0.3 1.7 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 KXT00194.1 - 2e-90 302.1 0.6 4.3e-90 301.0 0.6 1.5 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain Oxysterol_BP PF01237.18 KXT00194.1 - 3.3e-62 210.5 9.2 4.5e-61 206.7 6.5 2.9 3 1 0 3 3 3 1 Oxysterol-binding protein DUF3819 PF12842.7 KXT00194.1 - 1.9e-45 154.4 2.8 1.9e-45 154.4 2.8 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3819) CNOT1_HEAT PF16418.5 KXT00194.1 - 1.3e-37 129.2 0.6 5.3e-37 127.2 0.6 2.2 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat CNOT1_TTP_bind PF16417.5 KXT00194.1 - 1.7e-31 108.9 0.0 6.5e-31 107.0 0.0 2.0 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain AA_permease PF00324.21 KXT00197.1 - 6.4e-89 298.7 30.7 7.9e-89 298.4 30.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXT00197.1 - 5.9e-21 74.8 34.1 6.9e-21 74.6 34.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXT00198.1 - 6.4e-89 298.7 30.7 7.9e-89 298.4 30.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXT00198.1 - 5.9e-21 74.8 34.1 6.9e-21 74.6 34.1 1.0 1 0 0 1 1 1 1 Amino acid permease CorA PF01544.18 KXT00199.1 - 6.1e-13 48.7 0.8 1e-12 48.0 0.1 1.7 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein ABC2_membrane_5 PF13346.6 KXT00199.1 - 0.081 12.5 2.7 0.12 11.9 2.7 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Zn_clus PF00172.18 KXT00200.1 - 5.7e-11 42.4 10.4 1.2e-10 41.3 10.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXT00200.1 - 6e-05 22.2 0.2 0.00015 20.9 0.2 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Pyr_redox_3 PF13738.6 KXT00201.1 - 1.5e-14 54.0 0.0 5.2e-12 45.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KXT00201.1 - 1.9e-13 49.7 0.0 6.6e-06 24.8 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KXT00201.1 - 1.5e-10 40.7 0.1 3.9e-08 32.8 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KXT00201.1 - 4.6e-10 39.2 0.0 4e-08 32.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXT00201.1 - 0.0013 18.9 0.0 0.0043 17.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KXT00201.1 - 0.0025 17.8 0.1 0.21 11.6 0.0 3.1 3 1 1 4 4 4 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KXT00201.1 - 0.0051 15.9 0.0 0.036 13.1 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain HemeBinding_Shp PF11545.8 KXT00201.1 - 0.084 12.9 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Cell surface heme-binding protein Shp DAO PF01266.24 KXT00201.1 - 0.21 11.1 0.6 1.5 8.4 0.3 2.4 2 1 0 3 3 3 0 FAD dependent oxidoreductase Ras PF00071.22 KXT00202.1 - 6.2e-50 169.0 0.0 7.2e-50 168.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXT00202.1 - 8.7e-22 77.6 0.0 1.3e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXT00202.1 - 4.3e-07 29.6 0.0 5.9e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KXT00202.1 - 0.0011 18.5 0.0 0.0063 16.1 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KXT00202.1 - 0.014 14.7 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KXT00202.1 - 0.031 13.7 0.0 0.044 13.2 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 KXT00202.1 - 0.033 13.9 0.0 2.4 7.9 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.6 KXT00202.1 - 0.2 11.4 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system MFS_1 PF07690.16 KXT00203.1 - 1.5e-21 76.7 48.5 1.1e-13 50.9 22.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXT00203.1 - 1.2e-06 27.4 16.8 0.00065 18.4 2.6 2.1 2 0 0 2 2 2 2 MFS/sugar transport protein MWFE PF15879.5 KXT00203.1 - 5.4 7.3 5.1 1.1 9.5 0.1 2.5 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase MWFE subunit Mgm101p PF06420.12 KXT00206.1 - 7e-86 286.0 0.0 9.4e-86 285.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Preseq_ALAS PF09029.10 KXT00206.1 - 0.38 11.3 8.8 0.11 13.0 2.2 2.2 2 0 0 2 2 2 0 5-aminolevulinate synthase presequence MSA-2c PF12238.8 KXT00206.1 - 1.2 9.1 6.4 0.17 11.9 0.2 2.0 2 0 0 2 2 2 0 Merozoite surface antigen 2c Mgm101p PF06420.12 KXT00207.1 - 7e-86 286.0 0.0 9.4e-86 285.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Preseq_ALAS PF09029.10 KXT00207.1 - 0.38 11.3 8.8 0.11 13.0 2.2 2.2 2 0 0 2 2 2 0 5-aminolevulinate synthase presequence MSA-2c PF12238.8 KXT00207.1 - 1.2 9.1 6.4 0.17 11.9 0.2 2.0 2 0 0 2 2 2 0 Merozoite surface antigen 2c BTB PF00651.31 KXT00210.1 - 1.3e-07 31.8 0.0 2.7e-07 30.8 0.0 1.5 1 1 0 1 1 1 1 BTB/POZ domain Glyco_hydro_88 PF07470.13 KXT00212.1 - 6.2e-67 226.1 7.5 7.9e-67 225.8 7.5 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_88 PF07470.13 KXT00213.1 - 6.2e-67 226.1 7.5 7.9e-67 225.8 7.5 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 NST1 PF13945.6 KXT00214.1 - 1.1e-52 179.0 0.1 1.1e-52 179.0 0.1 4.8 3 1 0 3 3 3 1 Salt tolerance down-regulator COX14 PF14880.6 KXT00216.1 - 2.5e-15 56.0 0.2 5.8e-15 54.9 0.2 1.7 1 0 0 1 1 1 1 Cytochrome oxidase c assembly Peptidase_S24 PF00717.23 KXT00217.1 - 2.4e-08 33.8 0.0 3.4e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like IBR PF01485.21 KXT00218.1 - 1.5e-15 57.2 20.8 1e-09 38.5 5.9 4.1 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 KXT00218.1 - 0.024 14.5 27.3 0.21 11.5 9.8 3.4 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FlgN PF05130.12 KXT00218.1 - 1 9.8 10.4 2.3 8.7 10.4 1.6 1 0 0 1 1 1 0 FlgN protein Prok-RING_4 PF14447.6 KXT00218.1 - 8.1 6.4 23.3 2 8.3 7.6 3.4 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KXT00218.1 - 9 6.4 17.5 13 5.9 3.0 3.3 2 1 0 2 2 2 0 RING-type zinc-finger Lactamase_B_2 PF12706.7 KXT00220.1 - 4.4e-31 108.0 0.0 2.8e-30 105.4 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KXT00220.1 - 4.5e-11 42.9 0.0 7.2e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KXT00220.1 - 0.26 11.2 6.8 0.47 10.4 2.9 3.0 3 1 0 3 3 3 0 Metallo-beta-lactamase superfamily Methyltransf_23 PF13489.6 KXT00221.1 - 2e-18 66.8 0.0 4.5e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXT00221.1 - 1.9e-14 54.1 0.0 4.9e-14 52.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXT00221.1 - 2.6e-14 53.7 0.0 8.1e-14 52.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXT00221.1 - 3.6e-14 53.3 0.0 1.1e-13 51.8 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXT00221.1 - 4.2e-14 52.6 0.0 7e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Pkinase PF00069.25 KXT00221.1 - 3.2e-09 36.5 0.0 5.6e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ubie_methyltran PF01209.18 KXT00221.1 - 6.6e-08 32.2 0.0 1.9e-07 30.7 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.7 KXT00221.1 - 0.00042 20.3 0.0 0.00072 19.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 KXT00221.1 - 0.00062 19.5 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 KXT00221.1 - 0.00063 19.3 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.20 KXT00221.1 - 0.0018 17.4 0.0 0.0027 16.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.6 KXT00221.1 - 0.0026 17.8 0.0 0.0045 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KXT00221.1 - 0.0056 16.1 0.0 0.0096 15.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 KXT00221.1 - 0.0086 15.8 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 KXT00221.1 - 0.092 12.2 0.0 0.42 10.1 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase Kinase-like PF14531.6 KXT00221.1 - 0.18 11.1 0.0 0.38 10.0 0.0 1.4 2 0 0 2 2 2 0 Kinase-like FCH PF00611.23 KXT00222.1 - 4.1e-13 49.4 0.0 1.1e-12 48.0 0.0 1.8 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 KXT00222.1 - 5.1e-12 45.2 0.0 1.4e-11 43.8 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KXT00222.1 - 1e-11 44.3 0.0 3.6e-10 39.4 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 KXT00222.1 - 6.6e-11 41.9 0.0 1.4e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain FAS_meander PF17951.1 KXT00222.1 - 0.14 11.9 0.1 0.5 10.2 0.4 1.6 2 0 0 2 2 2 0 Fatty acid synthase meander beta sheet domain Rapsyn_N PF10579.9 KXT00222.1 - 0.16 12.1 0.2 0.36 10.9 0.2 1.5 1 0 0 1 1 1 0 Rapsyn N-terminal myristoylation and linker region PP_kinase_N PF13089.6 KXT00222.1 - 0.17 12.2 0.1 0.86 10.0 0.0 2.2 2 0 0 2 2 2 0 Polyphosphate kinase N-terminal domain Goodbye PF17109.5 KXT00223.1 - 1.6e-06 28.5 0.0 2.2e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain PglZ PF08665.12 KXT00224.1 - 0.23 11.5 0.0 0.58 10.2 0.0 1.6 1 1 1 2 2 2 0 PglZ domain Nucleo_P87 PF07267.11 KXT00225.1 - 0.0082 15.1 5.4 0.014 14.3 5.4 1.3 1 0 0 1 1 1 1 Nucleopolyhedrovirus capsid protein P87 Ran-binding PF05508.11 KXT00239.1 - 5.8e-122 406.6 0.0 7.3e-122 406.2 0.0 1.1 1 0 0 1 1 1 1 RanGTP-binding protein DegQ PF08181.11 KXT00239.1 - 0.093 12.8 0.1 0.41 10.8 0.1 2.1 1 0 0 1 1 1 0 DegQ (SacQ) family TRI12 PF06609.13 KXT00240.1 - 9.7e-37 126.7 33.4 1.2e-36 126.3 33.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KXT00240.1 - 6.4e-19 68.1 53.2 6.4e-19 68.1 53.2 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXT00240.1 - 1.4e-11 43.9 29.2 1.8e-10 40.3 10.5 2.7 2 0 0 2 2 2 2 Sugar (and other) transporter CDO_I PF05995.12 KXT00241.1 - 2.1e-37 128.1 0.4 8.9e-37 126.0 0.4 1.8 1 1 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 KXT00241.1 - 0.0018 17.8 0.1 0.0025 17.3 0.1 1.3 1 1 0 1 1 1 1 PCO_ADO Ribosomal_S17_N PF16205.5 KXT00242.1 - 2.8e-33 114.1 0.2 4.8e-33 113.4 0.2 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 KXT00242.1 - 3.2e-26 91.2 0.2 7.2e-26 90.1 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S17 DNA_primase_lrg PF04104.14 KXT00243.1 - 1.6e-79 267.1 0.0 2.6e-79 266.4 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit DNA_primase_lrg PF04104.14 KXT00244.1 - 1.6e-79 267.1 0.0 2.6e-79 266.4 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit PEP_hydrolase PF09370.10 KXT00245.1 - 8.9e-132 438.2 0.4 1.2e-131 437.8 0.4 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate hydrolase-like Pkinase PF00069.25 KXT00246.1 - 2.1e-69 233.8 0.0 2.8e-69 233.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT00246.1 - 2e-30 105.9 0.0 2.6e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KXT00246.1 - 0.00065 18.8 0.1 0.019 13.9 0.0 2.0 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 KXT00246.1 - 0.0017 17.7 0.0 0.0039 16.6 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KXT00246.1 - 0.0071 16.3 0.0 0.016 15.1 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KXT00246.1 - 0.01 14.9 0.1 0.016 14.3 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 MMR_HSR1_Xtn PF16897.5 KXT00247.1 - 6.8e-40 135.4 0.2 6.8e-40 135.4 0.2 2.1 3 0 0 3 3 3 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 KXT00247.1 - 5.9e-21 74.7 0.1 2.1e-20 72.9 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.21 KXT00247.1 - 6.8e-20 70.9 0.1 1.5e-19 69.8 0.1 1.6 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 KXT00247.1 - 3.5e-09 36.4 0.1 1.7e-08 34.2 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KXT00247.1 - 0.0009 19.3 0.1 0.19 11.7 0.0 2.5 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 KXT00247.1 - 0.0016 18.0 0.1 9.9 5.6 0.0 3.7 2 2 1 3 3 3 2 Elongation factor Tu GTP binding domain MeaB PF03308.16 KXT00247.1 - 0.0034 16.4 0.6 0.019 14.0 0.1 2.1 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 KXT00247.1 - 0.1 12.5 0.5 5.6 6.8 0.0 3.0 2 1 1 3 3 3 0 RsgA GTPase MMR_HSR1_Xtn PF16897.5 KXT00248.1 - 6.8e-40 135.4 0.2 6.8e-40 135.4 0.2 2.1 3 0 0 3 3 3 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 KXT00248.1 - 5.9e-21 74.7 0.1 2.1e-20 72.9 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.21 KXT00248.1 - 6.8e-20 70.9 0.1 1.5e-19 69.8 0.1 1.6 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 KXT00248.1 - 3.5e-09 36.4 0.1 1.7e-08 34.2 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KXT00248.1 - 0.0009 19.3 0.1 0.19 11.7 0.0 2.5 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 KXT00248.1 - 0.0016 18.0 0.1 9.9 5.6 0.0 3.7 2 2 1 3 3 3 2 Elongation factor Tu GTP binding domain MeaB PF03308.16 KXT00248.1 - 0.0034 16.4 0.6 0.019 14.0 0.1 2.1 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 KXT00248.1 - 0.1 12.5 0.5 5.6 6.8 0.0 3.0 2 1 1 3 3 3 0 RsgA GTPase FUSC_2 PF13515.6 KXT00249.1 - 0.00027 21.0 10.3 0.013 15.6 1.4 2.5 1 1 1 2 2 2 2 Fusaric acid resistance protein-like YhhN PF07947.14 KXT00249.1 - 0.11 12.0 16.4 0.0097 15.5 8.9 2.0 1 1 1 2 2 2 0 YhhN family Peroxin-3 PF04882.12 KXT00250.1 - 0.014 14.4 3.6 0.36 9.8 0.0 2.2 2 0 0 2 2 2 0 Peroxin-3 MFS_1 PF07690.16 KXT00251.1 - 5.5e-45 153.8 50.7 2.6e-44 151.6 50.6 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXT00251.1 - 6.4e-10 38.5 11.5 6.4e-10 38.5 11.5 3.2 3 1 0 3 3 3 1 Sugar (and other) transporter His_Phos_1 PF00300.22 KXT00252.1 - 3.3e-18 66.1 0.3 5.3e-18 65.4 0.1 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ANAPC_CDC26 PF10471.9 KXT00252.1 - 0.012 16.4 1.4 0.03 15.1 1.4 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 GTP_EFTU PF00009.27 KXT00253.1 - 8.4e-43 146.2 0.0 1.7e-42 145.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KXT00253.1 - 3.6e-30 104.6 0.0 9.4e-30 103.2 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KXT00253.1 - 4.1e-05 23.9 0.1 0.00012 22.4 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KXT00253.1 - 0.0039 17.2 0.1 0.019 15.1 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Ndc1_Nup PF09531.10 KXT00253.1 - 1.4 7.5 5.8 2.4 6.8 5.8 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup UPF0261 PF06792.11 KXT00256.1 - 1.1e-166 554.8 0.1 1.3e-166 554.6 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) Pkinase PF00069.25 KXT00257.1 - 6.9e-05 22.3 0.0 0.0091 15.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain K_channel_TID PF07941.11 KXT00257.1 - 0.37 11.3 2.8 0.9 10.0 2.8 1.6 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Synaptobrevin PF00957.21 KXT00258.1 - 1.1e-30 105.3 1.4 1.2e-30 105.1 1.4 1.0 1 0 0 1 1 1 1 Synaptobrevin MCU PF04678.13 KXT00258.1 - 0.0032 17.6 0.0 0.0033 17.5 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial calcium uniporter AKNA PF12443.8 KXT00258.1 - 0.0068 17.0 0.1 0.0094 16.6 0.1 1.3 1 1 0 1 1 1 1 AT-hook-containing transcription factor Fzo_mitofusin PF04799.13 KXT00258.1 - 0.0078 15.8 0.3 0.0078 15.8 0.3 1.4 2 0 0 2 2 2 1 fzo-like conserved region DUF5098 PF17023.5 KXT00258.1 - 0.021 13.8 0.1 0.026 13.5 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5098) EMP24_GP25L PF01105.24 KXT00258.1 - 0.021 14.8 0.7 0.032 14.2 0.7 1.3 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD GP41 PF00517.17 KXT00258.1 - 0.035 14.0 0.0 0.042 13.7 0.0 1.1 1 0 0 1 1 1 0 Retroviral envelope protein Sec20 PF03908.13 KXT00258.1 - 0.042 13.8 0.0 0.059 13.3 0.0 1.1 1 0 0 1 1 1 0 Sec20 Prominin PF05478.11 KXT00258.1 - 0.072 11.0 0.1 0.091 10.7 0.1 1.1 1 0 0 1 1 1 0 Prominin NPV_P10 PF05531.12 KXT00258.1 - 0.12 12.9 0.1 0.16 12.5 0.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 KXT00258.1 - 0.16 12.4 0.1 6.3 7.3 0.0 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF2207 PF09972.9 KXT00258.1 - 0.16 10.7 0.0 0.17 10.6 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Cation_efflux PF01545.21 KXT00261.1 - 9.1e-46 156.1 8.2 1.4e-45 155.5 8.2 1.3 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KXT00261.1 - 0.00011 22.2 0.3 0.00057 20.0 0.0 2.3 2 0 0 2 2 2 1 Dimerisation domain of Zinc Transporter E1_FCCH PF16190.5 KXT00261.1 - 0.094 12.9 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-activating enzyme E1 FCCH domain SelP_N PF04592.14 KXT00261.1 - 2.2 7.6 23.6 0.72 9.2 0.1 3.3 3 0 0 3 3 3 0 Selenoprotein P, N terminal region Abhydrolase_2 PF02230.16 KXT00262.1 - 1.2e-60 205.0 0.0 1.4e-60 204.8 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KXT00262.1 - 1e-06 28.4 0.5 0.00016 21.2 0.0 2.4 3 0 0 3 3 3 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KXT00262.1 - 9e-06 25.1 0.1 0.031 13.5 0.0 2.9 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KXT00262.1 - 3.5e-05 23.7 0.0 0.19 11.6 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXT00262.1 - 6.8e-05 23.6 0.0 0.00011 22.9 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 KXT00262.1 - 0.0024 17.4 0.0 0.0039 16.8 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.13 KXT00262.1 - 0.0025 17.5 0.0 0.028 14.1 0.0 2.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Esterase PF00756.20 KXT00262.1 - 0.0031 17.2 0.0 0.0034 17.1 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.20 KXT00262.1 - 0.012 15.3 0.2 0.092 12.4 0.1 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KXT00262.1 - 0.061 13.4 0.0 0.093 12.8 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein Lipase_3 PF01764.25 KXT00262.1 - 0.088 12.7 0.0 0.19 11.6 0.0 1.6 1 1 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.8 KXT00262.1 - 0.11 12.0 0.1 0.25 10.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Cutinase PF01083.22 KXT00262.1 - 0.16 11.9 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Cutinase Myb_DNA-binding PF00249.31 KXT00263.1 - 7.8e-06 26.0 0.4 0.00026 21.1 0.0 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXT00263.1 - 7.7e-05 22.9 0.1 0.00018 21.7 0.1 1.7 1 1 0 1 1 1 1 Myb-like DNA-binding domain TRI12 PF06609.13 KXT00264.1 - 2.1e-55 188.3 29.7 2.8e-55 187.9 29.7 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KXT00264.1 - 3.5e-15 55.8 45.1 2.8e-14 52.8 42.0 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily HTH_Tnp_Tc5 PF03221.16 KXT00265.1 - 1.1e-12 47.8 0.1 2.3e-12 46.8 0.1 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KXT00265.1 - 1.1e-05 25.0 0.1 1.9e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain MarR PF01047.22 KXT00265.1 - 0.036 14.0 0.0 0.074 13.0 0.0 1.5 1 0 0 1 1 1 0 MarR family HTH_Tnp_4 PF13613.6 KXT00265.1 - 0.1 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_Crp_2 PF13545.6 KXT00265.1 - 0.18 11.8 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Rif1_N PF12231.8 KXT00266.1 - 5.9e-119 397.4 3.5 1.1e-118 396.5 3.5 1.5 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Aldose_epim PF01263.20 KXT00266.1 - 8.6e-42 143.5 0.0 1.2e-41 143.0 0.0 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase Gln-synt_C PF00120.24 KXT00267.1 - 1.4e-82 277.5 0.0 1.7e-82 277.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain adh_short_C2 PF13561.6 KXT00268.1 - 8.5e-52 176.0 1.0 5.6e-34 117.7 0.9 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXT00268.1 - 3e-46 157.3 1.8 4.6e-43 147.0 0.6 2.1 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.10 KXT00268.1 - 5.3e-14 52.5 0.5 7.5e-14 52.0 0.5 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXT00268.1 - 0.0044 16.5 0.1 0.0072 15.8 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXT00268.1 - 0.038 13.4 0.0 0.065 12.6 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Rad4 PF03835.15 KXT00269.1 - 1.1e-35 122.4 0.2 3e-35 121.1 0.2 1.7 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 KXT00269.1 - 2e-26 92.2 0.0 3.8e-26 91.3 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_2 PF10404.9 KXT00269.1 - 8.2e-19 68.3 0.3 8.2e-19 68.3 0.3 3.2 4 0 0 4 4 4 1 Rad4 beta-hairpin domain 2 BHD_1 PF10403.9 KXT00269.1 - 1.3e-18 66.5 0.1 2.6e-18 65.6 0.1 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 Transglut_core PF01841.19 KXT00269.1 - 0.019 15.4 0.0 0.09 13.2 0.0 2.2 1 1 0 1 1 1 0 Transglutaminase-like superfamily DUF1748 PF08520.10 KXT00270.1 - 1.8e-31 107.8 0.0 2e-31 107.7 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Med10 PF09748.9 KXT00271.1 - 2.5e-39 134.0 0.7 2.8e-39 133.8 0.7 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF3877 PF12993.7 KXT00271.1 - 0.0018 18.1 0.1 0.0022 17.9 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function, E. rectale Gene description (DUF3877) SSXT PF05030.12 KXT00271.1 - 0.018 14.6 1.8 0.52 10.0 0.3 2.3 2 0 0 2 2 2 0 SSXT protein (N-terminal region) FANCF PF11107.8 KXT00271.1 - 0.089 12.0 0.0 0.098 11.9 0.0 1.1 1 0 0 1 1 1 0 Fanconi anemia group F protein (FANCF) DUF5343 PF17278.2 KXT00271.1 - 0.099 12.7 0.2 1.3 9.1 0.0 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5343) Glyco_transf_90 PF05686.12 KXT00272.1 - 1.5e-13 50.4 8.7 2.6e-12 46.3 4.8 2.8 2 1 0 2 2 2 2 Glycosyl transferase family 90 Sugar_tr PF00083.24 KXT00273.1 - 2.5e-85 287.0 17.9 2.8e-85 286.9 17.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXT00273.1 - 2.5e-23 82.6 30.5 8e-17 61.2 7.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KXT00273.1 - 0.00033 19.6 0.2 0.00033 19.6 0.2 2.6 1 1 2 3 3 3 2 MFS_1 like family KIX_2 PF16987.5 KXT00274.1 - 1.5e-12 47.3 3.3 1.5e-12 47.3 3.3 2.8 2 0 0 2 2 2 1 KIX domain HEAT_EZ PF13513.6 KXT00274.1 - 0.039 14.5 0.5 2.3 8.8 0.0 3.2 2 0 0 2 2 2 0 HEAT-like repeat LIN52 PF10044.9 KXT00274.1 - 0.044 14.5 7.0 0.065 13.9 0.9 4.2 2 0 0 2 2 2 0 Retinal tissue protein Transferase PF02458.15 KXT00275.1 - 1.9e-23 82.8 0.0 2.5e-18 66.0 0.0 2.9 2 1 0 2 2 2 2 Transferase family Transferase PF02458.15 KXT00276.1 - 1.9e-23 82.8 0.0 2.5e-18 66.0 0.0 2.9 2 1 0 2 2 2 2 Transferase family Myb_DNA-binding PF00249.31 KXT00278.1 - 0.047 13.9 0.1 0.099 12.8 0.1 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KXT00278.1 - 0.11 12.8 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain adh_short_C2 PF13561.6 KXT00279.1 - 4.5e-58 196.6 0.2 5.2e-58 196.4 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXT00279.1 - 4.4e-41 140.5 0.1 5.3e-41 140.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXT00279.1 - 3.1e-07 30.5 0.5 5e-07 29.8 0.5 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KXT00279.1 - 0.00022 21.1 0.2 0.00046 20.1 0.2 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 KXT00279.1 - 0.0016 19.1 0.0 0.0033 18.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXT00279.1 - 0.0019 18.9 0.0 0.0041 17.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Polysacc_synt_2 PF02719.15 KXT00279.1 - 0.021 14.0 0.0 0.035 13.2 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ADH_zinc_N PF00107.26 KXT00279.1 - 0.038 14.0 0.2 0.28 11.2 0.2 2.2 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Methyltransf_11 PF08241.12 KXT00279.1 - 0.072 13.7 0.0 0.14 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RecC_C PF17946.1 KXT00279.1 - 0.077 12.8 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 RecC C-terminal domain NAD_binding_10 PF13460.6 KXT00279.1 - 0.83 9.5 4.0 0.92 9.4 1.9 2.2 2 1 0 2 2 2 0 NAD(P)H-binding Lyase_1 PF00206.20 KXT00280.1 - 4.5e-114 381.0 0.0 7.9e-114 380.2 0.0 1.4 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 KXT00280.1 - 3.7e-21 75.3 0.0 8.9e-21 74.1 0.0 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus Ric8 PF10165.9 KXT00281.1 - 3.6e-130 435.1 0.0 4.8e-130 434.7 0.0 1.2 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn LigB PF02900.18 KXT00282.1 - 2.5e-34 118.6 0.0 3e-34 118.3 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase PrpR_N PF06506.11 KXT00282.1 - 0.15 11.6 0.0 0.38 10.3 0.0 1.6 2 0 0 2 2 2 0 Propionate catabolism activator MPC PF03650.13 KXT00283.1 - 1.4e-45 154.0 0.4 3.1e-45 152.9 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial pyruvate carriers MT0933_antitox PF14013.6 KXT00283.1 - 0.025 14.9 5.2 0.025 14.9 5.2 1.9 2 0 0 2 2 2 0 MT0933-like antitoxin protein LigB PF02900.18 KXT00284.1 - 2e-30 105.8 0.0 2.4e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase PrpR_N PF06506.11 KXT00284.1 - 0.16 11.5 0.0 0.41 10.2 0.0 1.6 2 0 0 2 2 2 0 Propionate catabolism activator HSP9_HSP12 PF04119.12 KXT00285.1 - 1.1e-17 64.1 5.6 1.1e-17 64.1 5.6 2.2 2 0 0 2 2 2 1 Heat shock protein 9/12 Tape_meas_lam_C PF09718.10 KXT00285.1 - 1.5 9.0 6.2 2.4 8.3 2.6 2.7 1 1 1 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) PXA PF02194.15 KXT00286.1 - 2e-42 145.2 0.1 3.8e-42 144.3 0.1 1.5 1 0 0 1 1 1 1 PXA domain L51_S25_CI-B8 PF05047.16 KXT00287.1 - 6.6e-16 58.0 0.0 8.2e-16 57.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain LEF-8 PF04941.12 KXT00291.1 - 0.09 11.0 0.1 0.099 10.9 0.1 1.0 1 0 0 1 1 1 0 Late expression factor 8 (LEF-8) DnaJ PF00226.31 KXT00292.1 - 2.2e-13 50.1 0.0 3.6e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain DUF2497 PF10691.9 KXT00292.1 - 0.097 13.1 0.0 12 6.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2497) Dynamin_N PF00350.23 KXT00293.1 - 0.0015 18.7 0.0 0.0051 16.9 0.0 2.0 1 1 0 1 1 1 1 Dynamin family LapD_MoxY_N PF16448.5 KXT00293.1 - 0.019 14.9 0.6 0.14 12.1 0.8 2.3 2 0 0 2 2 2 0 LapD/MoxY periplasmic domain AAA_16 PF13191.6 KXT00293.1 - 0.09 13.2 0.1 0.69 10.3 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain Lipase_GDSL_3 PF14606.6 KXT00293.1 - 0.12 12.5 0.3 0.33 11.1 0.3 1.8 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family RsgA_GTPase PF03193.16 KXT00293.1 - 0.3 11.0 1.5 4.9 7.0 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase MRP-L28 PF09812.9 KXT00293.1 - 0.52 10.4 3.2 0.22 11.6 0.3 1.9 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L28 DUF2229 PF09989.9 KXT00293.1 - 1.8 8.2 5.0 3.4 7.3 1.2 2.4 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) Mit_KHE1 PF10173.9 KXT00293.1 - 2 8.5 3.6 4.7 7.3 0.5 2.4 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related GEN1_C PF18380.1 KXT00294.1 - 2.2e-30 105.6 0.0 2.2e-30 105.6 0.0 3.1 2 1 0 2 2 2 1 Holliday junction resolvase Gen1 C-terminal domain XPG_I PF00867.18 KXT00294.1 - 3.6e-25 88.1 0.0 8.4e-25 87.0 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KXT00294.1 - 3.8e-08 33.7 0.0 9.4e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 KXT00294.1 - 0.0074 15.8 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing MRC1 PF09444.10 KXT00295.1 - 1.5e-24 87.2 23.6 1.5e-24 87.2 23.6 7.2 5 2 3 8 8 8 1 MRC1-like domain F-box-like PF12937.7 KXT00297.1 - 3.9e-10 39.5 0.7 7.5e-10 38.6 0.2 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXT00297.1 - 6.1e-07 29.2 0.1 1.1e-06 28.3 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KXT00297.1 - 0.016 15.1 0.1 0.032 14.1 0.1 1.5 1 0 0 1 1 1 0 F-box DUF5427 PF10310.9 KXT00298.1 - 4.3e-160 533.7 2.2 5.3e-160 533.4 2.2 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5427) MSA-2c PF12238.8 KXT00298.1 - 9.3 6.2 7.6 20 5.1 7.6 1.5 1 0 0 1 1 1 0 Merozoite surface antigen 2c Sugar_tr PF00083.24 KXT00299.1 - 4.8e-78 263.0 31.4 6.7e-78 262.6 31.4 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXT00299.1 - 1.5e-18 66.9 37.3 1.1e-14 54.1 21.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Kringle PF00051.18 KXT00299.1 - 0.045 14.1 0.2 0.093 13.1 0.2 1.4 1 0 0 1 1 1 0 Kringle domain Kinesin PF00225.23 KXT00301.1 - 5.5e-113 377.3 0.0 7.4e-113 376.8 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXT00301.1 - 1.9e-26 92.8 0.0 5.5e-26 91.3 0.0 1.8 2 0 0 2 2 2 1 Microtubule binding AAA_16 PF13191.6 KXT00301.1 - 0.08 13.3 0.9 0.37 11.1 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain PhoU PF01895.19 KXT00301.1 - 1.5 9.3 5.2 0.43 11.1 1.2 2.2 2 0 0 2 2 2 0 PhoU domain MRP-L28 PF09812.9 KXT00301.1 - 4.5 7.4 8.6 13 5.9 0.0 3.2 2 1 1 3 3 3 0 Mitochondrial ribosomal protein L28 Sel1 PF08238.12 KXT00302.1 - 4.2e-32 109.9 28.6 8.9e-07 29.4 0.7 13.0 13 0 0 13 13 13 7 Sel1 repeat TPR_7 PF13176.6 KXT00302.1 - 0.0021 18.0 2.1 12 6.2 0.0 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXT00302.1 - 0.017 15.2 7.5 13 6.2 0.0 7.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXT00302.1 - 0.024 15.2 9.9 29 5.6 0.0 7.1 7 0 0 7 7 7 0 Tetratricopeptide repeat LapA_dom PF06305.11 KXT00302.1 - 0.062 13.1 0.3 0.062 13.1 0.3 1.7 2 0 0 2 2 1 0 Lipopolysaccharide assembly protein A domain Phage_holin_2_4 PF16082.5 KXT00302.1 - 0.08 12.7 0.5 0.28 10.9 0.5 1.9 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like FeoB_associated PF12669.7 KXT00302.1 - 0.15 12.5 0.0 0.43 11.0 0.0 1.8 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein TPR_17 PF13431.6 KXT00302.1 - 0.19 12.2 1.3 51 4.6 0.0 4.2 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KXT00302.1 - 0.31 11.3 9.4 1.8 8.9 0.1 5.5 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXT00302.1 - 0.73 9.8 0.0 0.73 9.8 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat CcmD PF04995.14 KXT00302.1 - 1.1 9.4 4.4 2.5 8.2 4.4 1.6 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) TPR_8 PF13181.6 KXT00302.1 - 4.9 7.6 10.2 4.6 7.7 0.0 5.1 6 0 0 6 6 4 0 Tetratricopeptide repeat Lipase_3 PF01764.25 KXT00303.1 - 5.4e-07 29.6 0.0 1.3e-06 28.3 0.0 1.7 2 1 0 2 2 2 1 Lipase (class 3) Abhydrolase_2 PF02230.16 KXT00303.1 - 0.014 15.2 0.1 0.02 14.7 0.1 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Fungal_trans_2 PF11951.8 KXT00304.1 - 2.5e-07 29.8 0.1 1.7e-06 27.1 0.1 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain LRR_4 PF12799.7 KXT00305.1 - 0.00032 21.0 0.2 0.0006 20.1 0.2 1.5 1 1 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXT00305.1 - 0.0034 17.1 0.6 0.037 13.8 0.1 2.0 1 1 0 2 2 2 1 Leucine rich repeat DUF2237 PF09996.9 KXT00308.1 - 1.2e-28 99.3 0.1 1.4e-28 99.2 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) ADH_zinc_N PF00107.26 KXT00309.1 - 0.0009 19.2 0.1 0.0015 18.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXT00309.1 - 0.1 12.5 0.0 0.32 10.9 0.0 1.8 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain MFS_1 PF07690.16 KXT00310.1 - 1.4e-35 122.9 39.0 1.4e-35 122.9 39.0 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily ADH_N PF08240.12 KXT00311.1 - 1.1e-26 92.9 1.9 1.6e-26 92.3 1.9 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXT00311.1 - 9.4e-20 70.9 0.0 1.4e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXT00311.1 - 4.6e-06 26.3 0.0 6.8e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Sacchrp_dh_NADP PF03435.18 KXT00311.1 - 5.6e-06 26.7 0.0 8.2e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ADH_zinc_N_2 PF13602.6 KXT00311.1 - 0.011 16.8 0.0 0.018 16.1 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Shikimate_DH PF01488.20 KXT00311.1 - 0.034 14.2 0.0 0.066 13.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 KXT00311.1 - 0.039 13.3 0.4 0.23 10.8 0.1 2.0 2 0 0 2 2 2 0 ThiF family DAO PF01266.24 KXT00311.1 - 0.049 13.2 0.1 0.11 12.1 0.1 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_3 PF03447.16 KXT00311.1 - 0.057 14.1 0.0 0.1 13.2 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Fungal_trans PF04082.18 KXT00312.1 - 4.7e-12 45.5 2.0 9.1e-12 44.6 2.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain COG5 PF10392.9 KXT00313.1 - 0.00042 20.5 1.7 0.0014 18.8 1.7 1.9 1 1 0 1 1 1 1 Golgi transport complex subunit 5 COG7 PF10191.9 KXT00313.1 - 0.0077 14.5 0.2 0.023 13.0 0.0 1.7 2 0 0 2 2 2 1 Golgi complex component 7 (COG7) Baculo_PEP_C PF04513.12 KXT00313.1 - 0.013 15.6 4.4 0.013 15.6 4.4 1.9 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FapA PF03961.13 KXT00313.1 - 0.28 9.7 2.8 0.13 10.9 0.1 1.6 2 0 0 2 2 2 0 Flagellar Assembly Protein A WXG100 PF06013.12 KXT00313.1 - 0.36 11.1 2.4 16 5.8 0.3 3.1 3 0 0 3 3 3 0 Proteins of 100 residues with WXG bZIP_1 PF00170.21 KXT00313.1 - 0.69 10.1 2.9 18 5.5 0.6 2.6 1 1 1 2 2 2 0 bZIP transcription factor DUF4795 PF16043.5 KXT00313.1 - 1.3 8.6 7.5 63 3.1 7.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Cob_adeno_trans PF01923.18 KXT00313.1 - 1.4 9.0 5.4 4.5 7.4 0.6 2.2 1 1 0 2 2 2 0 Cobalamin adenosyltransferase LPP PF04728.13 KXT00313.1 - 1.8 9.0 3.8 40 4.7 1.3 3.2 1 1 1 2 2 2 0 Lipoprotein leucine-zipper Isochorismatase PF00857.20 KXT00314.1 - 2.5e-25 89.7 0.1 4.2e-25 88.9 0.1 1.4 1 1 0 1 1 1 1 Isochorismatase family PPR_3 PF13812.6 KXT00315.1 - 1.2e-05 25.2 0.0 0.22 11.6 0.0 3.0 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR_2 PF13041.6 KXT00315.1 - 0.016 15.4 0.0 0.098 12.9 0.0 2.4 2 0 0 2 2 2 0 PPR repeat family CLTH PF10607.9 KXT00316.1 - 6e-27 94.4 0.1 1.1e-26 93.5 0.1 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 KXT00316.1 - 1.7e-24 86.2 0.3 7.7e-24 84.1 0.1 2.1 2 0 0 2 2 2 1 SPRY domain LisH PF08513.11 KXT00316.1 - 0.00044 20.1 0.0 0.00099 19.0 0.0 1.6 1 0 0 1 1 1 1 LisH Amino_oxidase PF01593.24 KXT00317.1 - 1.4e-50 172.9 0.1 2.1e-50 172.4 0.1 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXT00317.1 - 4.5e-15 55.6 0.8 8.7e-15 54.7 0.2 1.8 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Ribonuc_L-PSP PF01042.21 KXT00317.1 - 1.5e-14 54.0 0.0 3e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Endoribonuclease L-PSP DAO PF01266.24 KXT00317.1 - 3.5e-07 30.1 1.0 3.5e-07 30.1 1.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXT00317.1 - 4e-07 29.5 1.9 7.1e-07 28.7 1.9 1.4 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KXT00317.1 - 9e-07 28.6 0.3 1.2e-06 28.2 0.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXT00317.1 - 1.3e-06 27.9 0.0 2.5e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KXT00317.1 - 6.6e-06 25.6 0.1 1e-05 24.9 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXT00317.1 - 4.4e-05 22.9 1.0 7.5e-05 22.1 1.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KXT00317.1 - 8.5e-05 23.0 0.4 0.00017 22.1 0.4 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXT00317.1 - 0.00035 19.4 0.2 0.00051 18.9 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.12 KXT00317.1 - 0.00093 18.3 1.7 0.0011 18.1 0.5 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KXT00317.1 - 0.0015 17.8 0.6 0.036 13.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXT00317.1 - 0.006 15.7 0.3 0.0093 15.1 0.3 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KXT00317.1 - 0.036 14.1 0.6 0.13 12.2 0.2 2.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 KXT00317.1 - 0.094 12.0 0.1 0.14 11.4 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF521 PF04412.13 KXT00317.1 - 0.11 11.2 0.0 0.21 10.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Trp_halogenase PF04820.14 KXT00317.1 - 0.14 11.0 0.2 7 5.4 0.3 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Glyco_hydro_16 PF00722.21 KXT00318.1 - 5.4e-21 74.8 5.8 1.2e-20 73.7 5.8 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 WSC PF01822.19 KXT00318.1 - 3.8e-14 52.6 8.1 2.4e-13 50.1 8.1 2.6 1 0 0 1 1 1 1 WSC domain LysM PF01476.20 KXT00318.1 - 7.3e-05 22.7 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 LysM domain IL6Ra-bind PF09240.10 KXT00318.1 - 0.11 12.9 0.1 0.11 12.9 0.1 2.2 2 0 0 2 2 2 0 Interleukin-6 receptor alpha chain, binding RPA43_OB PF17875.1 KXT00319.1 - 3.3e-16 60.0 0.1 9.3e-15 55.3 0.0 2.3 1 1 1 2 2 2 2 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 KXT00319.1 - 0.00089 19.6 0.0 0.0016 18.8 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RPA43_OB PF17875.1 KXT00320.1 - 3.3e-16 60.0 0.1 9.3e-15 55.3 0.0 2.3 1 1 1 2 2 2 2 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 KXT00320.1 - 0.00089 19.6 0.0 0.0016 18.8 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 COX5B PF01215.19 KXT00321.1 - 2.5e-60 201.8 0.0 3.4e-60 201.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb A2L_zn_ribbon PF08792.10 KXT00321.1 - 0.025 14.3 0.2 0.042 13.6 0.2 1.4 1 0 0 1 1 1 0 A2L zinc ribbon domain PARP PF00644.20 KXT00322.1 - 4.3e-10 39.5 0.2 9.2e-10 38.4 0.2 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.26 KXT00322.1 - 4.2e-06 26.4 0.0 8.6e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme INO80_Ies4 PF08193.11 KXT00324.1 - 9.4e-58 196.1 20.2 1.3e-57 195.6 20.2 1.1 1 0 0 1 1 1 1 INO80 complex subunit Ies4 DAGK_cat PF00781.24 KXT00328.1 - 0.11 12.1 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain TolA_bind_tri PF16331.5 KXT00329.1 - 0.059 13.4 11.9 0.16 12.1 0.2 2.7 2 0 0 2 2 2 0 TolA binding protein trimerisation MCC-bdg_PDZ PF10506.9 KXT00329.1 - 0.21 11.6 8.9 0.15 12.1 2.3 2.6 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF2570 PF10828.8 KXT00329.1 - 0.32 10.8 14.2 2.8 7.8 6.7 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2570) UPF0242 PF06785.11 KXT00329.1 - 0.5 10.4 16.5 0.38 10.8 10.6 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Snapin_Pallidin PF14712.6 KXT00329.1 - 2.3 8.7 9.9 7.1 7.1 6.2 2.7 2 0 0 2 2 2 0 Snapin/Pallidin DUF1664 PF07889.12 KXT00329.1 - 2.6 8.1 8.0 15 5.6 5.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ZapB PF06005.12 KXT00329.1 - 3.3 8.2 19.2 1.8 9.1 0.2 3.3 2 1 0 2 2 2 0 Cell division protein ZapB DUF745 PF05335.13 KXT00329.1 - 5.5 6.7 11.3 0.91 9.2 2.5 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF745) AA_kinase PF00696.28 KXT00330.1 - 3.3e-41 141.5 0.0 7.3e-41 140.3 0.0 1.6 1 1 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.6 KXT00330.1 - 7.4e-11 41.7 0.7 4e-08 32.9 0.1 2.6 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 KXT00330.1 - 1.4e-10 40.8 0.8 1.2e-06 28.2 0.1 2.7 2 0 0 2 2 2 2 ACT domain PI-PLC-C1 PF16670.5 KXT00331.1 - 2.2e-129 431.2 0.0 2.5e-129 431.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoinositide phospholipase C, Ca2+-dependent Ank_2 PF12796.7 KXT00333.1 - 3.5e-34 117.2 3.7 1.3e-10 41.7 0.0 5.1 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 KXT00333.1 - 7.4e-16 57.8 6.1 0.0065 16.9 0.0 7.3 7 0 0 7 7 7 4 Ankyrin repeat Ank_4 PF13637.6 KXT00333.1 - 8.4e-16 58.1 0.8 1.7e-05 25.2 0.1 5.1 2 2 3 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXT00333.1 - 9.9e-15 53.2 0.2 0.38 11.4 0.0 8.3 8 0 0 8 8 8 3 Ankyrin repeat NACHT PF05729.12 KXT00333.1 - 2.3e-10 40.6 0.9 2.6e-09 37.2 0.9 2.6 1 1 0 1 1 1 1 NACHT domain Ank_5 PF13857.6 KXT00333.1 - 7.2e-08 32.5 1.5 0.11 12.9 0.0 5.6 2 1 4 6 6 6 3 Ankyrin repeats (many copies) AAA_16 PF13191.6 KXT00333.1 - 2e-05 25.0 0.1 8.6e-05 23.0 0.1 2.1 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 KXT00333.1 - 0.043 14.2 0.0 0.16 12.4 0.0 2.0 1 0 0 1 1 1 0 RNA helicase DUF1908 PF08926.11 KXT00333.1 - 0.064 12.3 1.9 0.075 12.1 0.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1908) HSF_DNA-bind PF00447.17 KXT00334.1 - 3.3e-27 94.9 2.1 5.3e-27 94.3 0.1 2.3 2 0 0 2 2 2 1 HSF-type DNA-binding Spc7 PF08317.11 KXT00334.1 - 0.0058 15.5 4.7 0.06 12.2 0.8 2.3 2 0 0 2 2 2 2 Spc7 kinetochore protein TMF_TATA_bd PF12325.8 KXT00334.1 - 0.032 14.5 4.4 0.049 13.9 1.2 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Seryl_tRNA_N PF02403.22 KXT00334.1 - 0.13 12.5 5.6 0.18 12.1 2.4 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain HemX PF04375.14 KXT00334.1 - 0.21 10.9 6.2 4 6.6 0.1 2.5 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase TMF_DNA_bd PF12329.8 KXT00334.1 - 0.24 11.4 6.7 1.7 8.7 2.3 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding NPV_P10 PF05531.12 KXT00334.1 - 0.51 10.8 2.5 1.7 9.2 0.4 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF3450 PF11932.8 KXT00334.1 - 0.62 9.3 7.2 1.8 7.8 3.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Fib_alpha PF08702.10 KXT00334.1 - 1.4 9.1 8.0 2.9 8.1 0.0 2.8 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family APG6_N PF17675.1 KXT00334.1 - 1.5 9.4 11.9 0.17 12.4 4.9 2.6 3 0 0 3 3 3 0 Apg6 coiled-coil region DivIC PF04977.15 KXT00334.1 - 3.4 7.5 6.8 24 4.8 3.2 2.9 2 0 0 2 2 2 0 Septum formation initiator FliT PF05400.13 KXT00334.1 - 5.6 7.8 8.4 6.1 7.7 0.7 2.7 2 0 0 2 2 2 0 Flagellar protein FliT p450 PF00067.22 KXT00335.1 - 2.6e-68 230.9 0.0 3.7e-68 230.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Gly_transf_sug PF04488.15 KXT00335.1 - 3.6e-18 66.0 0.0 9.5e-18 64.6 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif PrgI PF12666.7 KXT00335.1 - 0.53 11.0 0.1 0.53 11.0 0.1 3.1 3 0 0 3 3 3 0 PrgI family protein LapA_dom PF06305.11 KXT00335.1 - 1.2 9.0 5.1 11 5.9 0.2 3.2 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain DUF3746 PF12562.8 KXT00336.1 - 0.069 13.1 0.0 0.091 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3746) RAI1 PF08652.11 KXT00338.1 - 1.1e-23 83.2 0.0 2.1e-23 82.3 0.0 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease RAI1 PF08652.11 KXT00339.1 - 1.1e-23 83.2 0.0 2.1e-23 82.3 0.0 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease RRM_1 PF00076.22 KXT00340.1 - 0.051 13.4 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fimbrillin_C PF15495.6 KXT00340.1 - 0.089 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Major fimbrial subunit protein type IV, Fimbrillin, C-terminal Sugar_tr PF00083.24 KXT00341.1 - 1e-108 364.1 24.7 1.2e-108 363.9 24.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXT00341.1 - 1.2e-24 86.9 35.7 2.2e-16 59.7 8.0 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily CbtA PF09490.10 KXT00341.1 - 3.8 7.2 10.1 4.5 7.0 5.1 3.0 3 0 0 3 3 3 0 Probable cobalt transporter subunit (CbtA) Pkinase PF00069.25 KXT00342.1 - 2.5e-58 197.5 0.0 3.6e-58 197.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT00342.1 - 9.8e-25 87.3 0.0 1.4e-24 86.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXT00342.1 - 6.9e-06 25.6 0.1 1.6e-05 24.4 0.1 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KXT00342.1 - 3.6e-05 22.7 0.0 6.3e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KXT00342.1 - 0.0014 18.0 0.0 0.0092 15.3 0.0 2.0 2 0 0 2 2 2 1 Kinase-like YrbL-PhoP_reg PF10707.9 KXT00342.1 - 0.016 14.7 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 KXT00342.1 - 0.31 10.9 2.7 0.29 11.0 0.1 2.0 2 1 0 2 2 2 0 Phosphotransferase enzyme family Rit1_C PF17184.4 KXT00343.1 - 8.9e-97 323.8 0.0 1.8e-96 322.8 0.0 1.5 2 0 0 2 2 2 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 KXT00343.1 - 5.8e-29 100.6 0.5 2.1e-28 98.8 0.0 2.2 3 0 0 3 3 3 1 Rit1 DUSP-like domain Shikimate_DH PF01488.20 KXT00343.1 - 0.024 14.7 0.4 6.9 6.7 0.0 3.6 4 0 0 4 4 4 0 Shikimate / quinate 5-dehydrogenase SGS PF05002.15 KXT00344.1 - 2.7e-30 104.3 0.8 1e-29 102.4 0.5 2.2 2 0 0 2 2 2 1 SGS domain CS PF04969.16 KXT00344.1 - 1.2e-12 48.7 0.0 2.2e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 CS domain TPR_19 PF14559.6 KXT00344.1 - 2.3e-07 31.2 1.4 0.0048 17.4 0.1 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXT00344.1 - 6.6e-06 26.7 0.7 0.017 15.7 0.2 2.5 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXT00344.1 - 7.5e-06 25.7 2.2 0.83 9.9 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KXT00344.1 - 0.00082 19.6 1.8 0.0044 17.3 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXT00344.1 - 0.0016 18.1 0.4 0.15 11.8 0.1 2.6 2 1 0 2 2 2 1 TPR repeat ANAPC3 PF12895.7 KXT00344.1 - 0.021 15.1 0.9 0.43 10.8 0.1 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KXT00344.1 - 0.025 15.4 0.4 6.7 7.8 0.0 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXT00344.1 - 0.11 12.8 0.5 12 6.4 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat UL73_N PF12522.8 KXT00344.1 - 2.1 8.2 13.5 4.2 7.2 13.5 1.5 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein N terminal Exo_endo_phos PF03372.23 KXT00345.1 - 0.00017 21.2 0.0 0.00062 19.4 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CcmF_C PF16327.5 KXT00345.1 - 0.064 12.5 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c-type biogenesis protein CcmF C-terminal LCCL PF03815.19 KXT00346.1 - 2.8e-19 69.0 0.1 4.6e-19 68.3 0.1 1.3 1 0 0 1 1 1 1 LCCL domain MTHFR PF02219.17 KXT00347.1 - 1.9e-100 335.9 0.0 3e-100 335.2 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DUF3295 PF11702.8 KXT00347.1 - 0.0016 17.9 0.5 0.0025 17.3 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) MmgE_PrpD PF03972.14 KXT00349.1 - 7.7e-115 383.9 0.5 9.5e-115 383.6 0.5 1.1 1 0 0 1 1 1 1 MmgE/PrpD family Glyco_hydro_43 PF04616.14 KXT00350.1 - 9.5e-68 228.6 7.2 1.2e-67 228.2 7.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KXT00350.1 - 2.9e-17 63.1 0.0 5.1e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain DUF5045 PF16464.5 KXT00350.1 - 0.16 12.3 0.0 0.32 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5045) Reg_prop PF07494.11 KXT00350.1 - 0.21 11.9 1.5 35 5.1 0.1 3.0 2 0 0 2 2 2 0 Two component regulator propeller Tau95 PF09734.9 KXT00351.1 - 6.1e-34 117.8 0.3 1.3e-33 116.8 0.3 1.5 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 KXT00351.1 - 8.6e-33 113.2 0.1 1.6e-32 112.4 0.1 1.4 1 0 0 1 1 1 1 Tau95 Triple barrel domain TPR_2 PF07719.17 KXT00352.1 - 3.6e-09 36.0 0.5 0.002 18.1 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXT00352.1 - 1.8e-07 30.7 1.1 0.065 13.1 0.1 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXT00352.1 - 5.3e-06 27.0 0.2 0.0059 17.2 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXT00352.1 - 2.8e-05 24.0 3.9 0.014 15.5 0.0 4.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXT00352.1 - 0.00019 21.6 0.3 0.26 11.6 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXT00352.1 - 0.00066 19.3 0.1 0.023 14.3 0.1 2.6 2 0 0 2 2 2 1 TPR repeat TPR_19 PF14559.6 KXT00352.1 - 0.0033 17.9 0.2 0.17 12.4 0.0 2.8 3 1 0 3 3 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXT00352.1 - 0.013 16.3 0.3 1.7 9.6 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 KXT00352.1 - 0.016 15.4 0.0 0.89 9.7 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KXT00352.1 - 0.019 14.4 0.2 0.036 13.4 0.2 1.5 1 1 0 1 1 1 0 MalT-like TPR region TPR_6 PF13174.6 KXT00352.1 - 0.077 13.7 0.3 1.7 9.4 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Cu_amine_oxid PF01179.20 KXT00353.1 - 3.3e-160 533.5 0.0 4e-160 533.2 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KXT00353.1 - 2e-19 69.9 0.2 1e-18 67.5 0.1 2.2 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KXT00353.1 - 1e-10 41.7 0.0 1.9e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Aldedh PF00171.22 KXT00354.1 - 8.2e-34 116.9 4.4 1e-20 73.7 1.2 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family DUF3813 PF12758.7 KXT00354.1 - 0.06 13.7 0.1 18 5.8 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3813) ParA PF10609.9 KXT00355.1 - 6.5e-91 304.2 0.0 8.4e-91 303.8 0.0 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KXT00355.1 - 1.9e-12 47.4 0.0 3e-11 43.5 0.0 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 KXT00355.1 - 1.6e-07 30.9 0.0 7.4e-07 28.7 0.0 1.8 2 0 0 2 2 2 1 ATPase MipZ ArsA_ATPase PF02374.15 KXT00355.1 - 9e-07 28.4 0.9 6e-05 22.4 0.1 2.2 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.6 KXT00355.1 - 1.4e-05 25.1 0.3 0.00018 21.5 0.3 2.2 1 1 0 1 1 1 1 AAA domain AAA_26 PF13500.6 KXT00355.1 - 0.00023 21.0 1.1 0.049 13.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KXT00355.1 - 0.0023 17.6 0.8 0.004 16.7 0.1 1.7 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 KXT00355.1 - 0.0024 16.9 0.1 0.0039 16.2 0.1 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CBP_BcsQ PF06564.12 KXT00355.1 - 0.0059 16.1 0.3 0.024 14.1 0.3 1.8 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ SRP54 PF00448.22 KXT00355.1 - 0.053 13.1 0.1 2.2 7.9 0.1 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 KXT00355.1 - 0.057 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 KXT00355.1 - 0.11 12.9 0.4 0.23 11.8 0.2 1.6 2 0 0 2 2 2 0 AAA ATPase domain APS_kinase PF01583.20 KXT00355.1 - 0.12 12.3 0.1 0.19 11.6 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase CLP1_P PF16575.5 KXT00355.1 - 0.14 11.9 0.1 0.49 10.2 0.0 1.8 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop RsgA_GTPase PF03193.16 KXT00355.1 - 0.17 11.8 1.6 0.39 10.6 1.0 1.8 2 0 0 2 2 2 0 RsgA GTPase tRNA_int_endo PF01974.17 KXT00356.1 - 1.4e-16 60.4 0.2 3.4e-16 59.1 0.2 1.7 1 1 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 KXT00356.1 - 1.3e-07 31.2 0.0 0.0007 19.2 0.0 2.5 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain B2 PF11473.8 KXT00356.1 - 0.17 11.7 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 RNA binding protein B2 DUF410 PF04190.13 KXT00358.1 - 4.1e-91 305.3 0.0 1.1e-90 303.9 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF410) DCP1 PF06058.13 KXT00359.1 - 1.7e-28 98.9 0.2 2.6e-28 98.3 0.2 1.3 1 0 0 1 1 1 1 Dcp1-like decapping family DraK_HK_N PF18092.1 KXT00359.1 - 0.045 14.2 0.5 0.089 13.2 0.5 1.4 1 0 0 1 1 1 0 DraK Histidine Kinase N-terminal domain DHHA2 PF02833.14 KXT00360.1 - 1.1e-35 122.9 0.0 2.2e-35 121.9 0.0 1.5 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 KXT00360.1 - 2.4e-09 37.3 0.0 4.5e-09 36.5 0.0 1.5 1 1 0 1 1 1 1 DHH family Ig_GlcNase PF18368.1 KXT00361.1 - 1.2e-33 115.4 0.0 4.5e-33 113.5 0.0 2.1 2 0 0 2 2 2 1 Exo-beta-D-glucosaminidase Ig-fold domain Glyco_hydro_2 PF00703.21 KXT00361.1 - 1.5e-11 44.9 0.1 1.5e-11 44.9 0.1 2.8 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 Mannosidase_ig PF17786.1 KXT00361.1 - 8.9e-06 26.2 1.2 6.7e-05 23.4 0.2 2.8 3 0 0 3 3 3 1 Mannosidase Ig/CBM-like domain Ig_mannosidase PF17753.1 KXT00361.1 - 0.0044 16.7 0.4 0.055 13.2 0.0 2.9 3 0 0 3 3 3 1 Ig-fold domain Invasin_D3 PF09134.10 KXT00361.1 - 0.19 12.1 2.1 2 8.8 1.0 2.8 2 0 0 2 2 2 0 Invasin, domain 3 PQ-loop PF04193.14 KXT00362.1 - 8.1e-37 124.8 7.6 1.1e-19 69.9 1.6 2.3 2 0 0 2 2 2 2 PQ loop repeat NMN_transporter PF04973.12 KXT00362.1 - 0.87 9.5 6.8 0.43 10.5 3.0 2.3 3 0 0 3 3 3 0 Nicotinamide mononucleotide transporter PAN_1 PF00024.26 KXT00363.1 - 2.4e-05 24.2 4.3 0.013 15.4 0.0 3.4 3 0 0 3 3 3 2 PAN domain DUF2780 PF11075.8 KXT00363.1 - 0.00051 20.2 17.4 1.2 9.2 0.8 6.4 4 2 1 5 5 5 3 Protein of unknown function VcgC/VcgE (DUF2780) PAN_4 PF14295.6 KXT00363.1 - 0.0011 18.8 13.6 0.0013 18.6 0.5 3.5 3 0 0 3 3 3 2 PAN domain Baculo_PEP_C PF04513.12 KXT00363.1 - 0.0054 16.8 6.7 0.012 15.6 0.0 3.8 3 1 0 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus B56 PF01603.20 KXT00364.1 - 3.2e-191 635.8 6.0 4.1e-191 635.4 6.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) GATase_5 PF13507.6 KXT00364.1 - 1.4e-99 332.5 0.1 2.5e-99 331.6 0.0 1.5 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain FGAR-AT_N PF18076.1 KXT00364.1 - 5.2e-33 113.5 0.0 1.2e-32 112.3 0.0 1.7 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal AIRS_C PF02769.22 KXT00364.1 - 1.2e-32 113.2 0.2 1.1e-22 80.9 0.0 2.5 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_linker PF18072.1 KXT00364.1 - 5.3e-23 81.3 0.0 1.2e-22 80.1 0.0 1.7 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain Sec7_N PF12783.7 KXT00364.1 - 0.039 13.9 1.2 8.1 6.3 0.0 2.3 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal CFEM PF05730.11 KXT00371.1 - 5.5e-12 45.6 15.8 5.5e-12 45.6 15.8 2.3 2 0 0 2 2 2 1 CFEM domain CFEM PF05730.11 KXT00372.1 - 5.5e-12 45.6 15.8 5.5e-12 45.6 15.8 2.3 2 0 0 2 2 2 1 CFEM domain IMS PF00817.20 KXT00373.1 - 8.2e-39 133.0 0.0 1.7e-38 132.0 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family REV1_C PF16727.5 KXT00373.1 - 1.2e-25 89.7 1.5 2.6e-25 88.6 1.5 1.6 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain UBM PF14377.6 KXT00373.1 - 1e-19 69.3 21.4 3.4e-10 39.0 3.4 4.3 5 0 0 5 5 5 3 Ubiquitin binding region IMS_C PF11799.8 KXT00373.1 - 2e-11 44.6 0.0 4.5e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 KXT00373.1 - 2.8e-10 40.4 0.0 1.2e-09 38.4 0.0 2.2 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KXT00373.1 - 2.7e-05 24.5 0.0 8.8e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KXT00373.1 - 0.0001 22.5 0.0 0.00027 21.2 0.0 1.7 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain IMS_HHH PF11798.8 KXT00373.1 - 0.00063 19.9 0.2 0.01 16.1 0.1 2.9 2 0 0 2 2 2 1 IMS family HHH motif PTCB-BRCT PF12738.7 KXT00373.1 - 0.00098 19.0 0.0 0.002 18.1 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain mCpol PF18182.1 KXT00373.1 - 0.011 16.0 0.0 0.031 14.6 0.0 1.7 1 0 0 1 1 1 0 minimal CRISPR polymerase domain RCC_reductase PF06405.11 KXT00373.1 - 0.12 11.5 0.0 0.26 10.4 0.0 1.4 1 0 0 1 1 1 0 Red chlorophyll catabolite reductase (RCC reductase) Cdd1 PF11731.8 KXT00373.1 - 0.12 12.6 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 Pathogenicity locus FliG_M PF14841.6 KXT00373.1 - 0.17 12.1 1.6 44 4.4 0.1 3.6 3 0 0 3 3 3 0 FliG middle domain MgtE_N PF03448.17 KXT00373.1 - 0.36 11.5 1.8 1e+02 3.6 0.0 4.0 4 0 0 4 4 4 0 MgtE intracellular N domain Bac_rhodopsin PF01036.18 KXT00374.1 - 2.1e-48 164.8 9.9 2.7e-48 164.5 9.9 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein PAP2_3 PF14378.6 KXT00374.1 - 0.65 9.6 9.2 0.19 11.4 0.5 2.8 2 1 0 2 2 2 0 PAP2 superfamily p450 PF00067.22 KXT00375.1 - 3.4e-51 174.4 0.0 7.1e-51 173.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 DUF1962 PF09227.10 KXT00376.1 - 0.69 10.3 12.2 0.14 12.6 8.9 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1962) BNR_2 PF13088.6 KXT00377.1 - 0.0013 18.1 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 KXT00377.1 - 0.014 15.2 2.5 0.48 10.6 0.5 3.2 2 0 0 2 2 2 0 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 KXT00377.1 - 0.041 12.7 0.3 6.7 5.4 0.0 2.3 2 0 0 2 2 2 0 Sortilin, neurotensin receptor 3, BNR_2 PF13088.6 KXT00378.1 - 0.00097 18.5 0.0 0.0015 17.9 0.0 1.4 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 KXT00378.1 - 0.0094 15.8 2.5 0.41 10.8 0.5 3.3 2 0 0 2 2 2 1 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 KXT00378.1 - 0.031 13.1 0.3 5.6 5.6 0.0 2.3 2 0 0 2 2 2 0 Sortilin, neurotensin receptor 3, BNR_2 PF13088.6 KXT00379.1 - 0.00099 18.5 0.0 0.0015 17.9 0.0 1.4 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 KXT00379.1 - 0.0098 15.8 2.5 0.41 10.8 0.5 3.3 2 0 0 2 2 2 1 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 KXT00379.1 - 0.029 13.2 0.3 5.7 5.6 0.0 2.4 2 0 0 2 2 2 0 Sortilin, neurotensin receptor 3, Man-6-P_recep PF02157.15 KXT00379.1 - 0.24 10.4 0.0 0.33 10.0 0.0 1.1 1 0 0 1 1 1 0 Mannose-6-phosphate receptor Adaptin_N PF01602.20 KXT00380.1 - 1.2e-136 456.4 4.0 1.4e-136 456.2 4.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KXT00380.1 - 2.6e-64 216.2 5.1 4.9e-62 208.8 1.0 2.8 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KXT00380.1 - 1.3e-13 51.1 9.2 4.7e-06 26.9 0.1 5.9 4 2 4 8 8 8 4 HEAT repeats HEAT PF02985.22 KXT00380.1 - 5.3e-12 44.9 3.4 0.0089 16.2 0.0 6.5 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.6 KXT00380.1 - 4e-05 24.0 1.8 0.9 10.1 0.0 6.4 6 1 1 7 7 7 1 HEAT-like repeat CLASP_N PF12348.8 KXT00380.1 - 0.0027 17.3 0.9 0.54 9.8 0.0 3.7 2 2 1 3 3 3 1 CLASP N terminal UNC45-central PF11701.8 KXT00380.1 - 0.0057 16.6 0.9 0.36 10.8 0.3 2.8 2 1 0 2 2 2 1 Myosin-binding striated muscle assembly central Arm PF00514.23 KXT00380.1 - 0.013 15.5 1.7 52 4.1 0.0 5.2 4 1 1 5 5 4 0 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 KXT00380.1 - 0.046 13.9 0.8 2.6 8.3 0.0 3.8 2 2 1 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 TIP120 PF08623.10 KXT00380.1 - 0.068 12.9 2.3 1.1 9.0 0.0 3.3 3 1 1 4 4 4 0 TATA-binding protein interacting (TIP20) Lar_N PF09861.9 KXT00380.1 - 0.1 11.8 0.3 2.8 7.0 0.0 2.3 2 0 0 2 2 2 0 Lactate racemase N-terminal domain Glyco_transf_20 PF00982.21 KXT00381.1 - 2.2e-199 663.0 0.0 2.7e-199 662.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.20 KXT00381.1 - 0.0015 18.1 0.4 0.031 13.8 0.0 2.6 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 KXT00381.1 - 0.012 15.3 0.1 0.025 14.3 0.1 1.5 1 0 0 1 1 1 0 Starch synthase catalytic domain Myc_N PF01056.18 KXT00381.1 - 0.061 13.2 1.5 0.094 12.6 1.5 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Ribosomal_60s PF00428.19 KXT00381.1 - 0.27 11.8 4.6 0.12 12.9 0.8 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Transp_cyt_pur PF02133.15 KXT00382.1 - 4.1e-94 315.9 40.8 4.7e-94 315.7 40.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Pkinase PF00069.25 KXT00383.1 - 1.5e-67 227.8 0.0 1.9e-67 227.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT00383.1 - 1.4e-31 109.7 0.0 1.9e-31 109.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KXT00383.1 - 0.00058 19.3 0.3 0.0014 18.0 0.3 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KXT00383.1 - 0.0065 15.4 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KXT00383.1 - 0.015 14.6 0.0 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KXT00383.1 - 0.036 14.0 0.0 0.094 12.6 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KXT00383.1 - 0.1 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF2183 PF09949.9 KXT00384.1 - 1.1e-20 73.7 0.2 2.7e-20 72.5 0.2 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) DUF1583 PF07622.11 KXT00384.1 - 0.14 10.9 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1583) ADH_zinc_N PF00107.26 KXT00386.1 - 7.8e-20 71.2 0.3 1.3e-19 70.5 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXT00386.1 - 1.3e-16 61.9 0.0 2.1e-16 61.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXT00386.1 - 2.6e-08 33.7 0.0 1.4e-06 28.1 0.0 2.7 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXT00387.1 - 7.8e-20 71.2 0.3 1.3e-19 70.5 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXT00387.1 - 1.3e-16 61.9 0.0 2.1e-16 61.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXT00387.1 - 2.6e-08 33.7 0.0 1.4e-06 28.1 0.0 2.7 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain MFS_1 PF07690.16 KXT00388.1 - 2.2e-34 119.0 28.8 2.2e-34 119.0 28.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MNSV_P7B PF06692.11 KXT00388.1 - 0.36 10.9 1.4 0.81 9.7 1.4 1.5 1 0 0 1 1 1 0 Melon necrotic spot virus P7B protein DUF632 PF04782.12 KXT00389.1 - 0.046 13.1 0.0 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF632) MFS_1 PF07690.16 KXT00391.1 - 9.1e-12 44.6 46.6 1.5e-07 30.7 10.5 3.3 2 1 1 3 3 3 2 Major Facilitator Superfamily TMPIT PF07851.13 KXT00391.1 - 0.057 12.7 0.8 0.1 11.8 0.8 1.4 1 0 0 1 1 1 0 TMPIT-like protein CSTF2_hinge PF14327.6 KXT00393.1 - 1.8e-28 98.8 2.8 5.4e-28 97.3 2.8 1.9 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 KXT00393.1 - 5.3e-21 74.2 0.0 9.1e-21 73.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 KXT00393.1 - 1.1e-06 28.1 2.7 6.8e-06 25.6 3.2 2.1 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal RRM_7 PF16367.5 KXT00393.1 - 0.015 15.4 0.0 0.034 14.3 0.0 1.6 1 1 0 1 1 1 0 RNA recognition motif SIS_2 PF13580.6 KXT00393.1 - 0.084 12.9 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 SIS domain RRM_occluded PF16842.5 KXT00393.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif AA_permease PF00324.21 KXT00394.1 - 5.7e-91 305.5 41.7 6.7e-91 305.3 41.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXT00394.1 - 8.6e-21 74.3 44.3 1.1e-20 73.9 44.3 1.0 1 0 0 1 1 1 1 Amino acid permease CH PF00307.31 KXT00395.1 - 4.7e-05 23.5 0.0 0.00014 22.0 0.0 1.8 2 0 0 2 2 2 1 Calponin homology (CH) domain DUF3431 PF11913.8 KXT00396.1 - 7e-84 280.9 0.4 9.3e-84 280.5 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) DUF3107 PF11305.8 KXT00396.1 - 0.14 12.4 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3107) KAR9 PF08580.10 KXT00397.1 - 1.2e-139 467.0 15.0 1.2e-139 467.0 15.0 2.3 3 0 0 3 3 3 1 Yeast cortical protein KAR9 KxDL PF10241.9 KXT00397.1 - 0.13 12.5 2.7 0.33 11.2 0.3 2.9 3 0 0 3 3 3 0 Uncharacterized conserved protein MIase PF02426.16 KXT00397.1 - 0.14 12.3 0.2 9.8 6.4 0.0 2.8 2 0 0 2 2 2 0 Muconolactone delta-isomerase DUF4795 PF16043.5 KXT00397.1 - 0.37 10.4 13.2 0.026 14.2 0.6 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4795) SVIP PF15811.5 KXT00397.1 - 7.6 7.1 9.0 32 5.1 9.0 2.1 1 0 0 1 1 1 0 Small VCP/p97-interacting protein FMO-like PF00743.19 KXT00398.1 - 1.7e-19 69.6 0.0 5e-19 68.1 0.0 1.7 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KXT00398.1 - 2.1e-13 50.2 0.0 4.1e-13 49.2 0.0 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXT00398.1 - 1.1e-11 44.6 0.1 5.5e-11 42.3 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXT00398.1 - 9.4e-11 41.8 0.0 4.8e-10 39.5 0.0 2.3 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KXT00398.1 - 3.3e-06 26.5 0.0 0.00039 19.7 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KXT00398.1 - 0.00034 20.3 1.4 0.96 9.0 0.4 3.7 2 2 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXT00398.1 - 0.004 17.7 0.1 4.6 7.9 0.1 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXT00398.1 - 0.0062 15.8 0.1 0.012 14.9 0.1 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 KXT00398.1 - 0.013 15.5 0.0 0.44 10.5 0.0 3.0 2 1 1 3 3 3 0 FAD-NAD(P)-binding DUF4390 PF14334.6 KXT00398.1 - 0.091 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4390) AlaDh_PNT_C PF01262.21 KXT00398.1 - 0.2 10.9 0.0 0.36 10.1 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KXT00398.1 - 0.26 10.3 0.4 0.53 9.3 0.1 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A FMO-like PF00743.19 KXT00399.1 - 1.6e-19 69.7 0.0 4.7e-19 68.2 0.0 1.7 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KXT00399.1 - 2e-13 50.3 0.0 3.9e-13 49.3 0.0 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXT00399.1 - 1e-11 44.7 0.1 5.2e-11 42.4 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXT00399.1 - 9.4e-11 41.8 0.0 4.6e-10 39.6 0.0 2.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KXT00399.1 - 3.1e-06 26.6 0.0 0.00036 19.8 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KXT00399.1 - 0.0003 20.5 1.5 0.92 9.0 0.4 3.6 2 2 1 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXT00399.1 - 0.0058 15.9 0.1 0.012 14.9 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 KXT00399.1 - 0.0081 16.7 1.3 4.4 7.9 0.1 3.0 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXT00399.1 - 0.012 15.6 0.0 0.42 10.6 0.0 3.0 2 1 1 3 3 3 0 FAD-NAD(P)-binding DUF4390 PF14334.6 KXT00399.1 - 0.089 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4390) AlaDh_PNT_C PF01262.21 KXT00399.1 - 0.2 10.9 0.0 0.35 10.1 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KXT00399.1 - 0.27 10.3 0.4 0.51 9.4 0.1 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A NPL PF17800.1 KXT00400.1 - 6.3e-33 113.5 0.0 6.3e-33 113.5 0.0 2.1 2 1 0 2 2 2 1 Nucleoplasmin-like domain FKBP_C PF00254.28 KXT00400.1 - 2.6e-32 111.0 0.0 6e-32 109.8 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Noggin PF05806.12 KXT00400.1 - 10 6.0 5.8 2.1 8.2 2.1 1.7 2 0 0 2 2 2 0 Noggin Epimerase PF01370.21 KXT00401.1 - 0.00035 20.1 0.0 0.00057 19.4 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family SpoU_sub_bind PF08032.12 KXT00401.1 - 0.13 12.5 0.0 0.51 10.6 0.0 1.9 1 1 1 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding Fasciclin PF02469.22 KXT00403.1 - 2.3e-36 124.8 0.4 6.1e-22 78.2 0.1 2.2 2 0 0 2 2 2 2 Fasciclin domain MFS_1 PF07690.16 KXT00405.1 - 1.6e-09 37.2 27.9 2.5e-09 36.5 27.9 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 KXT00405.1 - 7.2e-06 25.8 3.8 7.2e-06 25.8 3.8 2.9 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.24 KXT00405.1 - 0.00097 18.1 10.8 0.0022 16.9 10.8 1.6 1 0 0 1 1 1 1 Sugar (and other) transporter ComJ PF11033.8 KXT00405.1 - 0.033 13.9 0.1 0.33 10.7 0.0 2.1 2 0 0 2 2 2 0 Competence protein J (ComJ) Peroxidase_2 PF01328.17 KXT00407.1 - 1.3e-48 166.1 0.0 1.8e-48 165.6 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Mito_carr PF00153.27 KXT00408.1 - 6e-61 202.4 6.1 1.1e-19 70.1 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Apolipoprotein PF01442.18 KXT00408.1 - 0.043 13.7 3.0 0.069 13.0 3.0 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain HAP1_N PF04849.13 KXT00408.1 - 0.17 11.0 3.2 0.22 10.7 3.2 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region TBCA PF02970.16 KXT00408.1 - 0.24 11.8 2.3 0.42 11.0 2.3 1.3 1 0 0 1 1 1 0 Tubulin binding cofactor A Terminase_GpA PF05876.12 KXT00409.1 - 0.047 12.2 0.0 0.061 11.9 0.0 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) RNA_pol_Rbc25 PF08292.12 KXT00409.1 - 0.061 13.6 0.7 0.11 12.8 0.3 1.5 1 1 0 1 1 1 0 RNA polymerase III subunit Rpc25 Pkinase PF00069.25 KXT00411.1 - 3.2e-43 148.0 0.0 5.8e-43 147.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT00411.1 - 8.6e-26 90.8 0.0 1.7e-25 89.8 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase DUF3544 PF12064.8 KXT00413.1 - 0.022 15.0 1.8 0.028 14.7 1.8 1.0 1 0 0 1 1 1 0 Protein kinase C-binding protein 1 Pkinase PF00069.25 KXT00414.1 - 4.3e-12 45.9 0.0 1.4e-09 37.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXT00414.1 - 2.9e-05 23.5 0.0 0.00025 20.4 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase DEK_C PF08766.11 KXT00415.1 - 0.0034 17.3 0.0 0.0094 15.8 0.0 1.8 1 0 0 1 1 1 1 DEK C terminal domain ADH_zinc_N PF00107.26 KXT00416.1 - 5.1e-08 33.0 0.0 1e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXT00416.1 - 0.00032 21.7 0.0 0.00078 20.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXT00416.1 - 0.0012 18.7 0.0 0.0022 17.9 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Bac_luciferase PF00296.20 KXT00417.1 - 7.3e-51 173.4 0.0 9.7e-51 173.0 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Mannosyl_trans2 PF04188.13 KXT00429.1 - 2.7e-47 162.1 11.8 3.1e-47 161.9 11.8 1.0 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) CcmD PF04995.14 KXT00432.1 - 0.15 12.2 0.1 0.15 12.2 0.1 2.5 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) DUF1388 PF07142.12 KXT00432.1 - 2.7 8.0 9.1 18 5.4 0.9 4.1 3 0 0 3 3 3 0 Repeat of unknown function (DUF1388) Pro-kuma_activ PF09286.11 KXT00433.1 - 3.3e-35 121.5 0.1 4.9e-35 120.9 0.1 1.2 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KXT00433.1 - 0.0012 18.2 0.4 0.002 17.5 0.4 1.2 1 0 0 1 1 1 1 Subtilase family DUF998 PF06197.13 KXT00434.1 - 0.00019 21.1 13.4 0.0006 19.5 6.6 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF998) Amidohydro_1 PF01979.20 KXT00435.1 - 2.5e-41 142.2 0.1 2.9e-41 142.0 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXT00435.1 - 3.9e-09 36.5 0.6 2.4e-07 30.6 0.0 2.2 1 1 1 2 2 2 2 Amidohydrolase family Urocanase_C PF17392.2 KXT00435.1 - 0.00039 19.9 0.5 0.00091 18.7 0.4 1.6 1 1 0 1 1 1 1 Urocanase C-terminal domain Pterin_bind PF00809.22 KXT00435.1 - 0.099 12.3 0.1 0.13 11.9 0.1 1.1 1 0 0 1 1 1 0 Pterin binding enzyme SET PF00856.28 KXT00437.1 - 5.2e-05 23.7 0.0 0.00011 22.7 0.0 1.5 1 0 0 1 1 1 1 SET domain 2OG-FeII_Oxy PF03171.20 KXT00438.1 - 3.8e-19 69.0 0.0 7.7e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KXT00438.1 - 1.2e-13 51.8 0.0 1.8e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Vps36_ESCRT-II PF11605.8 KXT00439.1 - 0.0013 18.9 0.0 0.0053 16.9 0.0 1.9 2 0 0 2 2 2 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.20 KXT00439.1 - 0.038 13.9 0.0 0.059 13.3 0.0 1.3 1 0 0 1 1 1 0 GRAM domain DUF2052 PF09747.9 KXT00440.1 - 7.8e-25 88.2 21.6 2.6e-12 47.3 0.6 2.3 1 1 0 2 2 2 2 Coiled-coil domain containing protein (DUF2052) RBD-FIP PF09457.10 KXT00440.1 - 0.86 9.6 3.4 2 8.4 3.4 1.5 1 0 0 1 1 1 0 FIP domain MMR_HSR1 PF01926.23 KXT00441.1 - 4.4e-14 52.5 0.0 9.9e-14 51.4 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXT00441.1 - 2.9e-05 24.1 0.0 5.2e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 KXT00441.1 - 0.0023 18.0 0.1 0.11 12.5 0.2 2.3 1 1 1 2 2 2 1 Dynamin family FeoB_N PF02421.18 KXT00441.1 - 0.0029 17.1 0.0 0.0054 16.3 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B SMN PF06003.12 KXT00441.1 - 0.077 12.2 1.8 0.053 12.8 0.4 1.4 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) AAA_21 PF13304.6 KXT00441.1 - 0.12 12.2 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 KXT00441.1 - 0.13 12.8 0.0 0.24 11.9 0.0 1.6 1 1 0 1 1 1 0 ABC transporter DUF3712 PF12505.8 KXT00442.1 - 2.3e-09 37.6 0.0 1.6e-05 25.2 0.0 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF3712) LEA_2 PF03168.13 KXT00442.1 - 0.0046 17.5 0.5 0.85 10.2 0.1 3.7 4 0 0 4 4 4 1 Late embryogenesis abundant protein Cyclase PF04199.13 KXT00443.1 - 4.8e-15 56.0 0.4 7.6e-15 55.4 0.4 1.4 1 0 0 1 1 1 1 Putative cyclase Glyco_hydro81C PF17652.1 KXT00444.1 - 3.6e-148 493.5 6.8 4.7e-148 493.1 6.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 KXT00444.1 - 9.7e-97 324.0 2.4 2.6e-96 322.6 2.4 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain PIR PF00399.19 KXT00444.1 - 0.03 13.9 0.6 0.1 12.2 0.6 2.0 1 0 0 1 1 1 0 Yeast PIR protein repeat IMP2_N PF18590.1 KXT00444.1 - 0.039 14.5 0.1 0.43 11.2 0.0 2.7 2 0 0 2 2 2 0 Immune Mapped Protein 2 (IMP2) N-terminal domain Abhydrolase_3 PF07859.13 KXT00447.1 - 1.5e-42 145.9 0.0 2.4e-42 145.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold TauD PF02668.16 KXT00448.1 - 3.1e-43 148.5 0.1 4.1e-43 148.1 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Syja_N PF02383.18 KXT00448.1 - 0.081 12.2 0.0 0.094 12.0 0.0 1.2 1 0 0 1 1 1 0 SacI homology domain Abhydrolase_3 PF07859.13 KXT00449.1 - 1.5e-42 145.9 0.0 2.4e-42 145.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold TauD PF02668.16 KXT00450.1 - 3.1e-43 148.5 0.1 4.1e-43 148.1 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Syja_N PF02383.18 KXT00450.1 - 0.081 12.2 0.0 0.094 12.0 0.0 1.2 1 0 0 1 1 1 0 SacI homology domain TauD PF02668.16 KXT00451.1 - 3.1e-43 148.5 0.1 4.1e-43 148.1 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Syja_N PF02383.18 KXT00451.1 - 0.081 12.2 0.0 0.094 12.0 0.0 1.2 1 0 0 1 1 1 0 SacI homology domain K_oxygenase PF13434.6 KXT00452.1 - 7.9e-21 74.6 0.0 2.9e-14 53.0 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KXT00452.1 - 3.7e-12 46.1 0.0 1.1e-06 28.2 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXT00452.1 - 2.7e-11 43.3 0.0 3.7e-05 23.1 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXT00452.1 - 0.00018 21.2 0.2 0.011 15.3 0.0 3.2 1 1 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXT00452.1 - 0.00058 19.9 0.4 0.92 9.5 0.2 3.8 4 1 1 5 5 5 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KXT00452.1 - 0.0015 18.8 0.1 0.016 15.4 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KXT00452.1 - 0.0016 17.2 0.0 0.13 10.9 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 KXT00452.1 - 0.0016 17.7 0.0 0.009 15.3 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KXT00452.1 - 0.016 14.4 0.0 0.036 13.3 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 KXT00452.1 - 0.019 14.0 0.0 0.086 11.9 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 KXT00452.1 - 0.073 12.1 0.1 0.18 10.9 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 KXT00452.1 - 0.077 13.6 0.0 76 4.0 0.0 3.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase OTCace PF00185.24 KXT00453.1 - 4.6e-44 150.3 0.0 7.4e-44 149.6 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 KXT00453.1 - 1.1e-41 142.4 0.6 1.9e-41 141.5 0.6 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Glyco_transf_4 PF13439.6 KXT00453.1 - 0.17 11.8 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase Family 4 zf-met PF12874.7 KXT00454.1 - 0.036 14.5 0.0 0.12 12.8 0.0 2.0 1 0 0 1 1 1 0 Zinc-finger of C2H2 type OTCace PF00185.24 KXT00455.1 - 4.6e-44 150.3 0.0 7.4e-44 149.6 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 KXT00455.1 - 1.1e-41 142.4 0.6 1.9e-41 141.5 0.6 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Glyco_transf_4 PF13439.6 KXT00455.1 - 0.17 11.8 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase Family 4 zf-met PF12874.7 KXT00456.1 - 0.036 14.5 0.0 0.12 12.8 0.0 2.0 1 0 0 1 1 1 0 Zinc-finger of C2H2 type SUZ PF12752.7 KXT00457.1 - 5.6e-13 49.4 1.7 5.6e-13 49.4 1.7 3.8 3 1 1 4 4 4 1 SUZ domain R3H PF01424.22 KXT00457.1 - 9.4e-10 38.3 0.0 2.4e-09 37.0 0.0 1.8 1 0 0 1 1 1 1 R3H domain Piwi PF02171.17 KXT00458.1 - 3.7e-78 262.8 0.0 6.3e-78 262.1 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KXT00458.1 - 6.2e-17 62.5 0.1 1.3e-16 61.4 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KXT00458.1 - 4.3e-14 51.9 0.0 9.8e-14 50.8 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 KXT00458.1 - 3.7e-11 43.0 0.0 8.1e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 KXT00458.1 - 4.9e-08 33.2 0.0 1.4e-07 31.7 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 KXT00458.1 - 0.0034 17.6 0.1 0.01 16.1 0.1 1.9 1 1 0 1 1 1 1 Mid domain of argonaute ALS_ss_C PF10369.9 KXT00459.1 - 2.1e-14 53.5 0.0 1.8e-13 50.5 0.0 2.3 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 KXT00459.1 - 4.3e-14 52.0 0.1 7.9e-14 51.1 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 KXT00459.1 - 4.1e-08 32.9 0.0 6.7e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 ACT domain zf-CCHC_3 PF13917.6 KXT00460.1 - 8.7e-05 22.4 3.0 0.00033 20.5 2.9 2.0 1 1 1 2 2 2 1 Zinc knuckle ATP-synt_C PF00137.21 KXT00462.1 - 4e-10 39.9 11.8 7.3e-10 39.1 11.8 1.5 1 0 0 1 1 1 1 ATP synthase subunit C PilJ PF13675.6 KXT00462.1 - 0.14 12.1 4.7 0.23 11.5 4.7 1.5 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term YTH PF04146.15 KXT00463.1 - 1.8e-32 112.5 0.1 1.8e-32 112.5 0.1 3.4 2 2 0 2 2 2 1 YT521-B-like domain KIAA1430 PF13879.6 KXT00463.1 - 1.1 10.0 12.9 70 4.3 10.7 3.2 2 1 0 2 2 2 0 KIAA1430 homologue Macoilin PF09726.9 KXT00463.1 - 6.4 5.2 15.8 11 4.5 15.8 1.2 1 0 0 1 1 1 0 Macoilin family SMN PF06003.12 KXT00465.1 - 1.9 7.7 8.8 3 7.0 8.8 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) SAPS PF04499.15 KXT00467.1 - 1.1e-185 618.1 3.3 9.4e-185 615.0 0.0 2.4 2 1 0 2 2 2 1 SIT4 phosphatase-associated protein KH_1 PF00013.29 KXT00468.1 - 6.5e-07 29.1 0.0 0.00075 19.3 0.0 2.6 2 0 0 2 2 2 2 KH domain HET PF06985.11 KXT00469.1 - 2.1e-30 106.0 2.3 5.6e-30 104.6 0.2 2.6 3 0 0 3 3 3 1 Heterokaryon incompatibility protein (HET) Isochorismatase PF00857.20 KXT00470.1 - 1.3e-44 152.5 0.2 1.4e-44 152.3 0.2 1.0 1 0 0 1 1 1 1 Isochorismatase family AAA_25 PF13481.6 KXT00470.1 - 0.062 12.9 0.0 0.091 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain adh_short PF00106.25 KXT00471.1 - 7.9e-34 116.8 0.0 1.4e-33 116.0 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT00471.1 - 1.2e-24 87.2 0.0 2.1e-23 83.1 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT00471.1 - 0.0065 16.4 0.0 0.016 15.2 0.0 1.6 2 0 0 2 2 2 1 KR domain ENTH PF01417.20 KXT00472.1 - 1.4e-46 157.6 0.0 2.1e-46 157.0 0.0 1.3 1 0 0 1 1 1 1 ENTH domain DUF1720 PF08226.11 KXT00472.1 - 5e-05 23.6 42.2 5e-05 23.6 42.2 5.1 1 1 2 3 3 3 1 Domain of unknown function (DUF1720) ANTH PF07651.16 KXT00472.1 - 0.0059 15.6 0.0 0.0088 15.1 0.0 1.2 1 0 0 1 1 1 1 ANTH domain UIM PF02809.20 KXT00472.1 - 0.052 13.5 4.4 0.14 12.1 0.3 2.7 2 0 0 2 2 2 0 Ubiquitin interaction motif VHS PF00790.19 KXT00472.1 - 0.052 13.4 0.0 0.094 12.6 0.0 1.3 1 0 0 1 1 1 0 VHS domain DUF4264 PF14084.6 KXT00472.1 - 0.13 11.9 0.1 0.25 11.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) APH PF01636.23 KXT00473.1 - 4.5e-15 56.2 1.8 1.3e-14 54.7 1.8 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXT00473.1 - 7e-07 29.0 0.0 1.2e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KXT00473.1 - 0.0041 16.8 0.0 1.5 8.4 0.0 2.1 2 0 0 2 2 2 2 RIO1 family FAD_binding_4 PF01565.23 KXT00474.1 - 3.9e-22 78.5 0.1 6.1e-22 77.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Sod_Fe_C PF02777.18 KXT00475.1 - 2.5e-35 120.7 0.2 4.7e-35 119.8 0.2 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KXT00475.1 - 5e-30 103.8 1.8 1.7e-29 102.1 1.8 1.9 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain UCR_hinge PF02320.16 KXT00475.1 - 8.1e-16 58.0 3.4 1.9e-15 56.8 3.4 1.6 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein BUD22 PF09073.10 KXT00475.1 - 0.025 14.0 12.9 0.034 13.5 12.9 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 KXT00475.1 - 0.035 13.5 15.1 0.044 13.2 15.1 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KXT00475.1 - 1.2 7.3 19.1 1.6 6.9 19.1 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KXT00475.1 - 4 5.6 14.8 5.9 5.0 14.8 1.2 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 KXT00475.1 - 5.4 5.0 22.7 7.6 4.5 22.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi HA2 PF04408.23 KXT00475.1 - 7.4 6.9 5.7 20 5.5 5.7 2.0 1 1 0 1 1 1 0 Helicase associated domain (HA2) Zn-ribbon_8 PF09723.10 KXT00476.1 - 0.0034 17.4 1.0 0.0073 16.4 1.0 1.6 1 0 0 1 1 1 1 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 KXT00476.1 - 0.0097 15.9 3.1 2.6 8.1 0.7 2.5 2 0 0 2 2 2 2 Transposase zinc-ribbon domain BTB PF00651.31 KXT00476.1 - 0.018 15.3 0.0 0.073 13.3 0.0 1.9 2 0 0 2 2 2 0 BTB/POZ domain HypA PF01155.19 KXT00476.1 - 0.032 14.3 0.7 0.07 13.2 0.7 1.7 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA NiFeSe_Hases PF00374.19 KXT00476.1 - 0.11 11.3 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Nickel-dependent hydrogenase zf-C2H2_6 PF13912.6 KXT00476.1 - 0.36 10.9 0.3 0.36 10.9 0.3 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KXT00476.1 - 0.54 11.2 2.5 10 7.2 0.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Cupin_8 PF13621.6 KXT00480.1 - 3.2e-42 145.0 0.0 5.3e-42 144.3 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain LCM PF04072.14 KXT00480.1 - 2.7e-21 76.4 0.0 4.7e-21 75.6 0.0 1.4 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_5 PF13854.6 KXT00480.1 - 2.6e-09 36.9 0.0 7e-05 22.7 0.0 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 KXT00480.1 - 2.6e-08 33.8 10.8 0.03 14.3 0.0 5.9 6 0 0 6 6 6 3 Galactose oxidase, central domain Cupin_4 PF08007.12 KXT00480.1 - 4.4e-05 23.1 0.0 0.0001 21.9 0.0 1.5 1 0 0 1 1 1 1 Cupin superfamily protein Kelch_3 PF13415.6 KXT00480.1 - 0.029 14.7 6.1 11 6.5 0.0 4.6 4 0 0 4 4 4 0 Galactose oxidase, central domain Rho_GDI PF02115.17 KXT00481.1 - 1.6e-61 207.5 0.2 2e-61 207.2 0.2 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Fumerase_C PF05683.12 KXT00481.1 - 0.063 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Fumarase C-terminus DUF4452 PF14618.6 KXT00483.1 - 2.5e-67 226.0 9.7 3.3e-67 225.6 9.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) GDE_N PF12439.8 KXT00483.1 - 0.037 13.5 0.4 0.059 12.8 0.4 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme N terminal TRF PF08558.10 KXT00484.1 - 7.7e-58 195.9 0.0 1e-57 195.5 0.0 1.1 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.31 KXT00484.1 - 0.0036 17.4 0.0 0.0085 16.3 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF573 PF04504.14 KXT00484.1 - 0.099 13.3 0.0 0.55 10.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF573 DASH_Dad3 PF08656.10 KXT00485.1 - 3.3e-30 104.0 0.4 4.4e-30 103.6 0.4 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad3 DASH_Dad3 PF08656.10 KXT00486.1 - 3.3e-30 104.0 0.4 4.4e-30 103.6 0.4 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad3 Pkinase PF00069.25 KXT00487.1 - 3.2e-72 243.1 0.0 6.8e-72 242.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT00487.1 - 2.4e-30 105.7 0.0 4.1e-22 78.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KXT00487.1 - 3.6e-06 26.5 0.0 0.55 9.5 0.0 3.2 3 0 0 3 3 3 3 Kinase-like Kdo PF06293.14 KXT00487.1 - 0.02 14.2 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXT00487.1 - 0.037 13.9 0.0 0.51 10.2 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXT00487.1 - 0.094 11.5 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase SOBP PF15279.6 KXT00487.1 - 2.2 8.8 10.0 4.2 7.9 10.0 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein LRR_9 PF14580.6 KXT00488.1 - 2e-55 187.0 0.0 2.7e-55 186.6 0.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 KXT00488.1 - 4e-07 29.7 0.5 1.2e-06 28.2 0.5 1.9 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 KXT00488.1 - 5.1e-07 29.9 10.2 6.4e-06 26.4 2.4 3.3 2 2 1 3 3 3 2 Leucine Rich repeats (2 copies) Trimer_CC PF08954.11 KXT00488.1 - 0.035 13.6 0.0 0.073 12.6 0.0 1.5 1 0 0 1 1 1 0 Trimerisation motif ParB_C PF18064.1 KXT00488.1 - 0.17 12.0 0.0 0.36 11.0 0.0 1.5 1 0 0 1 1 1 0 Centromere-binding protein ParB C-terminal Thioredoxin PF00085.20 KXT00489.1 - 1.4e-28 98.9 0.3 1.8e-28 98.6 0.3 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 KXT00489.1 - 2.6e-05 23.7 0.1 3.4e-05 23.3 0.1 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 KXT00489.1 - 0.00015 22.0 0.0 0.0013 19.0 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 KXT00489.1 - 0.00023 20.9 0.0 0.0003 20.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KXT00489.1 - 0.00054 20.4 0.5 0.0045 17.4 0.5 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 KXT00489.1 - 0.0017 18.3 0.0 0.0019 18.1 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 KXT00489.1 - 0.012 15.8 0.3 0.019 15.1 0.3 1.5 1 1 0 1 1 1 0 Thioredoxin-like AhpC-TSA PF00578.21 KXT00489.1 - 0.048 13.6 0.1 0.11 12.4 0.1 1.5 1 1 0 1 1 1 0 AhpC/TSA family Phosducin PF02114.16 KXT00489.1 - 0.074 12.0 0.0 0.089 11.7 0.0 1.1 1 0 0 1 1 1 0 Phosducin Glutaredoxin PF00462.24 KXT00489.1 - 0.12 12.7 0.9 0.2 11.9 0.9 1.5 1 1 0 1 1 1 0 Glutaredoxin Dcc1 PF09724.9 KXT00490.1 - 3.8e-31 108.6 0.0 4.9e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 Cu-oxidase_3 PF07732.15 KXT00492.1 - 3.7e-41 139.9 2.9 1.3e-40 138.2 1.6 2.6 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KXT00492.1 - 2e-40 137.7 5.1 6.2e-40 136.1 0.2 3.3 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 KXT00492.1 - 2.9e-39 134.7 0.0 3.5e-38 131.2 0.3 2.5 2 0 0 2 2 2 1 Multicopper oxidase CFEM PF05730.11 KXT00493.1 - 5.4e-06 26.4 7.1 1e-05 25.5 7.1 1.5 1 0 0 1 1 1 1 CFEM domain DUF3307 PF11750.8 KXT00493.1 - 0.093 12.8 0.4 0.18 11.9 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3307) Babuvirus_MP PF07234.11 KXT00493.1 - 0.36 11.0 2.7 3.9 7.7 1.3 2.3 2 0 0 2 2 2 0 Movement and RNA silencing protein Glyco_trans_2_3 PF13632.6 KXT00494.1 - 1.7e-15 57.5 5.0 6.8e-15 55.5 5.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 KXT00494.1 - 6e-13 48.6 0.0 1.1e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 KXT00494.1 - 2.8e-07 30.6 0.0 5.4e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KXT00494.1 - 0.00014 21.7 0.0 0.00024 20.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Cellulose_synt PF03552.14 KXT00494.1 - 0.00014 20.6 0.3 0.0002 20.0 0.3 1.1 1 0 0 1 1 1 1 Cellulose synthase DUF3099 PF11298.8 KXT00494.1 - 0.16 12.1 5.5 10 6.3 0.1 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3099) Aldedh PF00171.22 KXT00495.1 - 2.3e-85 286.9 0.1 2.8e-85 286.6 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KXT00495.1 - 3.7e-05 23.0 0.0 9.9e-05 21.5 0.0 1.7 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF3071 PF11268.8 KXT00495.1 - 0.16 12.0 0.1 0.56 10.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3071) Use1 PF09753.9 KXT00497.1 - 4.6e-10 39.7 0.2 6e-10 39.3 0.2 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 SNARE PF05739.19 KXT00497.1 - 7.3e-09 35.5 1.4 1.5e-08 34.5 1.4 1.5 1 0 0 1 1 1 1 SNARE domain DUF5364 PF17322.2 KXT00497.1 - 0.0085 16.4 1.6 0.016 15.6 1.6 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5364) Rrn6 PF10214.9 KXT00497.1 - 0.082 11.4 4.3 0.1 11.1 4.3 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Cluap1 PF10234.9 KXT00497.1 - 0.39 10.1 4.5 1.4 8.3 0.5 2.2 2 1 0 2 2 2 0 Clusterin-associated protein-1 HrpB7 PF09486.10 KXT00497.1 - 2.2 8.6 9.7 7.6 6.9 5.7 3.0 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) GHMP_kinases_N PF00288.26 KXT00498.1 - 1.6e-17 63.5 0.6 4.1e-17 62.2 0.6 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KXT00498.1 - 1.1e-11 44.9 0.0 2.7e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal TFIIE-A_C PF11521.8 KXT00499.1 - 0.27 11.6 0.9 0.41 11.0 0.0 1.7 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha SNF2_N PF00176.23 KXT00500.1 - 1.1e-54 185.6 0.0 4.9e-54 183.4 0.0 1.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXT00500.1 - 1.2e-14 54.5 2.2 1.7e-13 50.8 0.0 3.3 4 0 0 4 4 4 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KXT00500.1 - 0.00029 20.1 0.4 0.00096 18.4 0.0 1.9 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 PHD PF00628.29 KXT00500.1 - 0.0012 18.7 6.4 0.0012 18.7 6.4 2.8 2 1 1 3 3 3 1 PHD-finger Zf_RING PF16744.5 KXT00500.1 - 0.011 15.8 1.4 0.011 15.8 1.4 3.3 2 1 1 3 3 3 0 KIAA1045 RING finger JHY PF15261.6 KXT00500.1 - 0.016 15.9 1.0 0.016 15.9 1.0 2.4 3 0 0 3 3 3 0 Jhy protein ERCC3_RAD25_C PF16203.5 KXT00500.1 - 0.091 12.0 0.0 12 5.1 0.0 2.4 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase zf-PHD-like PF15446.6 KXT00500.1 - 0.92 9.1 10.5 0.21 11.2 2.1 2.7 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain RhoGEF PF00621.20 KXT00501.1 - 3.3e-22 79.6 0.0 8.1e-22 78.3 0.0 1.6 1 0 0 1 1 1 1 RhoGEF domain DUF3507 PF12015.8 KXT00501.1 - 1e-05 25.4 0.0 2.1e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) Nod1 PF17114.5 KXT00501.1 - 0.0029 17.8 0.0 0.012 15.8 0.0 2.0 2 0 0 2 2 2 1 Gef2-related medial cortical node protein Nod1 TSC22 PF01166.18 KXT00501.1 - 0.18 12.1 0.5 1.3 9.4 0.5 2.5 1 0 0 1 1 1 0 TSC-22/dip/bun family Shugoshin_N PF07558.11 KXT00501.1 - 0.22 11.4 1.5 1.3 8.9 0.1 2.7 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region SHE3 PF17078.5 KXT00501.1 - 0.23 11.2 5.1 0.45 10.2 1.9 2.9 3 0 0 3 3 3 0 SWI5-dependent HO expression protein 3 DUF4407 PF14362.6 KXT00501.1 - 0.58 9.4 7.1 4.8 6.4 4.5 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Cep57_CLD_2 PF14197.6 KXT00502.1 - 0.029 14.5 1.0 0.029 14.5 1.0 2.8 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 Cnn_1N PF07989.11 KXT00502.1 - 0.11 12.7 2.2 0.45 10.7 0.3 2.6 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 Glyco_transf_10 PF00852.19 KXT00504.1 - 0.1 12.3 0.1 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 10 (fucosyltransferase) C-term Pyr_redox_2 PF07992.14 KXT00506.1 - 3.6e-43 147.9 0.0 5e-43 147.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXT00506.1 - 7.9e-14 52.0 0.0 5.4e-10 39.7 0.0 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 KXT00506.1 - 7e-06 25.2 0.1 2.2e-05 23.7 0.1 1.9 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KXT00506.1 - 3.6e-05 23.4 0.2 0.00014 21.5 0.2 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KXT00506.1 - 0.00023 21.5 0.1 0.00057 20.3 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KXT00506.1 - 0.00091 18.6 0.3 0.0023 17.3 0.3 1.8 1 0 0 1 1 1 1 EF hand Pyr_redox_3 PF13738.6 KXT00506.1 - 0.038 13.2 0.3 0.22 10.7 0.4 2.0 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.25 KXT00507.1 - 2.8e-31 108.9 0.0 5e-18 65.4 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXT00507.1 - 4.4e-14 52.4 0.0 4.3e-09 36.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 KXT00507.1 - 0.02 14.2 0.1 0.04 13.3 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KXT00507.1 - 0.067 12.0 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 KXT00507.1 - 0.083 12.5 0.0 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Clr2_transil PF16761.5 KXT00508.1 - 9e-25 87.3 0.4 1.9e-24 86.3 0.4 1.6 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Clr2 PF10383.9 KXT00508.1 - 6.5e-16 59.4 2.0 7.7e-15 55.9 0.3 2.9 2 1 0 2 2 2 1 Transcription-silencing protein Clr2 Glyco_hydro_31 PF01055.26 KXT00511.1 - 2.6e-112 376.2 2.0 3.4e-112 375.9 2.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KXT00511.1 - 1.7e-05 25.1 1.4 0.00019 21.7 0.2 3.1 2 1 0 2 2 2 1 Galactose mutarotase-like DUF4968 PF16338.5 KXT00511.1 - 0.00019 21.7 0.0 0.00034 20.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) DSPc PF00782.20 KXT00512.1 - 4.5e-28 97.7 0.0 2.2e-20 72.8 0.0 2.4 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KXT00512.1 - 3.9e-05 23.3 0.0 0.0028 17.3 0.0 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase CDKN3 PF05706.12 KXT00512.1 - 0.085 12.5 0.7 1.8 8.2 0.0 2.5 2 1 0 2 2 2 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) HTH_17 PF12728.7 KXT00512.1 - 0.13 12.5 0.1 0.6 10.3 0.0 2.2 2 1 0 2 2 2 0 Helix-turn-helix domain PNKP_ligase PF16542.5 KXT00513.1 - 0.075 12.5 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 PNKP adenylyltransferase domain, ligase domain COesterase PF00135.28 KXT00514.1 - 3.2e-86 290.2 0.0 2e-72 244.8 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KXT00514.1 - 1.3e-07 31.7 0.1 6.2e-07 29.5 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold PPR_2 PF13041.6 KXT00515.1 - 1.2e-40 137.4 1.8 1.9e-08 34.4 0.0 13.0 13 1 1 14 14 14 9 PPR repeat family PPR_3 PF13812.6 KXT00515.1 - 3.9e-34 116.5 0.0 0.00031 20.7 0.0 10.3 8 4 3 11 11 11 8 Pentatricopeptide repeat domain PPR_long PF17177.4 KXT00515.1 - 8.4e-18 64.5 14.7 8.2e-08 31.9 0.0 6.4 4 1 2 6 6 6 4 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 KXT00515.1 - 5e-17 61.3 4.3 8.8e-06 25.3 0.0 9.8 11 0 0 11 11 11 3 PPR repeat PPR PF01535.20 KXT00515.1 - 1.7e-15 56.1 33.2 0.0028 17.8 0.1 16.5 19 0 0 19 19 19 2 PPR repeat RPM2 PF08579.11 KXT00515.1 - 0.0062 16.9 0.0 0.17 12.3 0.0 3.4 4 0 0 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) TPR_14 PF13428.6 KXT00515.1 - 3.9 8.6 11.0 2.5 9.2 0.2 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 KXT00515.1 - 4.4 7.9 7.7 23 5.6 0.2 5.1 4 1 0 4 4 4 0 Tetratricopeptide repeat zf-TRAF PF02176.18 KXT00516.1 - 4.7e-09 36.8 19.3 0.0037 17.9 6.3 4.0 1 1 2 3 3 3 3 TRAF-type zinc finger zf-RING_2 PF13639.6 KXT00516.1 - 8.5e-07 29.2 13.7 8.5e-07 29.2 13.7 3.0 2 1 1 3 3 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KXT00516.1 - 1.2e-06 28.4 13.2 1.2e-06 28.4 13.2 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KXT00516.1 - 1.3e-06 28.2 11.3 1.3e-06 28.2 11.3 3.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXT00516.1 - 6e-06 26.1 11.0 6e-06 26.1 11.0 2.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KXT00516.1 - 0.00012 21.8 14.5 0.00012 21.8 14.5 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 KXT00516.1 - 0.00017 21.3 4.7 0.00068 19.4 4.7 2.0 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_3 PF13920.6 KXT00516.1 - 0.00071 19.4 10.0 0.00071 19.4 10.0 3.2 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KXT00516.1 - 0.0018 18.3 4.6 0.0059 16.6 4.6 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KXT00516.1 - 0.0023 18.0 12.9 0.0023 18.0 12.9 2.7 3 1 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-TRAF_2 PF15965.5 KXT00516.1 - 0.13 12.8 26.9 2 9.0 9.5 3.7 1 1 3 4 4 4 0 TRAF-like zinc-finger zf-rbx1 PF12678.7 KXT00516.1 - 0.54 10.6 17.7 0.037 14.3 9.3 3.0 2 1 0 2 2 2 0 RING-H2 zinc finger domain Sina PF03145.16 KXT00516.1 - 0.73 9.7 10.8 0.31 11.0 0.4 2.6 1 1 2 3 3 3 0 Seven in absentia protein family Nup54 PF13874.6 KXT00516.1 - 3.2 7.9 7.4 12 6.0 0.2 3.2 3 0 0 3 3 3 0 Nucleoporin complex subunit 54 Acetyltransf_3 PF13302.7 KXT00517.1 - 1.3e-16 61.5 0.0 1.5e-16 61.3 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXT00517.1 - 1.6e-14 54.1 0.0 2e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXT00517.1 - 1.1e-05 25.4 0.0 1.7e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXT00517.1 - 2.4e-05 24.7 0.0 3.4e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXT00517.1 - 0.00017 21.5 0.0 0.00041 20.2 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 KXT00517.1 - 0.052 13.2 0.0 0.083 12.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DBR1 PF05011.13 KXT00518.1 - 6.4e-40 136.8 0.2 1.2e-39 135.9 0.2 1.5 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 KXT00518.1 - 2.8e-06 28.0 1.2 3.4e-06 27.7 0.3 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Ta0938 PF11494.8 KXT00518.1 - 0.21 11.9 0.0 0.67 10.3 0.0 1.8 2 0 0 2 2 2 0 Ta0938 TSC22 PF01166.18 KXT00519.1 - 0.046 14.0 0.7 0.25 11.7 0.3 2.2 2 0 0 2 2 2 0 TSC-22/dip/bun family YabA PF06156.13 KXT00519.1 - 0.066 13.9 0.6 0.18 12.5 0.2 1.9 2 0 0 2 2 2 0 Initiation control protein YabA bZIP_2 PF07716.15 KXT00519.1 - 0.22 11.6 1.9 0.64 10.2 1.9 1.8 1 0 0 1 1 1 0 Basic region leucine zipper Shugoshin_N PF07558.11 KXT00519.1 - 0.31 11.0 2.7 0.54 10.2 2.7 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region TubC_N PF18563.1 KXT00519.1 - 0.35 10.9 3.7 10 6.2 0.7 2.3 2 0 0 2 2 2 0 TubC N-terminal docking domain ZapB PF06005.12 KXT00519.1 - 1.3 9.5 4.8 0.37 11.3 0.9 2.1 2 0 0 2 2 2 0 Cell division protein ZapB tRNA_int_end_N2 PF12928.7 KXT00520.1 - 1.9e-23 82.4 0.0 3.2e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_end_N2 PF12928.7 KXT00521.1 - 1.9e-23 82.4 0.0 3.2e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_end_N2 PF12928.7 KXT00522.1 - 1.9e-23 82.4 0.0 3.2e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term KilA-N PF04383.13 KXT00523.1 - 0.035 13.9 0.0 0.076 12.9 0.0 1.5 1 0 0 1 1 1 0 KilA-N domain Spore_III_AF PF09581.10 KXT00523.1 - 0.082 12.9 1.4 0.13 12.2 1.4 1.4 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Pox_D2 PF04701.13 KXT00524.1 - 0.11 12.6 0.5 0.3 11.3 0.0 1.9 2 0 0 2 2 2 0 Pox virus D2 protein GDA1_CD39 PF01150.17 KXT00525.1 - 1.9e-113 379.4 0.0 2.6e-113 378.9 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DsbD_2 PF13386.6 KXT00525.1 - 0.085 12.8 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Cytochrome C biogenesis protein transmembrane region DEADboxA PF12343.8 KXT00526.1 - 0.23 12.0 5.0 0.15 12.6 0.8 2.5 2 1 0 2 2 2 0 Cold shock protein DEAD box A Hemerythrin PF01814.23 KXT00527.1 - 3.5e-13 50.3 6.7 5.9e-13 49.6 6.7 1.4 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain ANAPC4_WD40 PF12894.7 KXT00528.1 - 0.0078 16.5 0.0 0.47 10.8 0.0 3.5 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXT00528.1 - 0.13 13.2 0.0 14 6.7 0.0 3.3 2 0 0 2 2 2 0 WD domain, G-beta repeat WD40_like PF17005.5 KXT00528.1 - 0.13 11.5 0.2 3.7 6.8 0.0 2.9 4 0 0 4 4 4 0 WD40-like domain Rpr2 PF04032.16 KXT00529.1 - 9.4e-07 29.0 1.7 1.9e-06 28.1 1.7 1.5 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain PP1_bind PF15276.6 KXT00529.1 - 0.14 12.5 0.8 0.38 11.1 0.8 1.7 1 0 0 1 1 1 0 Protein phosphatase 1 binding DUF678 PF05077.12 KXT00529.1 - 0.18 12.0 0.1 0.18 12.0 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF678) DIM1 PF02966.16 KXT00530.1 - 1.7e-69 231.7 0.3 1.9e-69 231.6 0.3 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 KXT00530.1 - 0.0012 18.8 0.0 0.0015 18.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KXT00530.1 - 0.017 15.4 0.6 0.035 14.4 0.6 1.6 1 1 0 1 1 1 0 Thioredoxin-like DUF3328 PF11807.8 KXT00538.1 - 1.6e-17 64.0 3.2 4.8e-17 62.5 3.2 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) adh_short PF00106.25 KXT00539.1 - 4.4e-44 150.3 0.0 5.5e-44 150.0 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT00539.1 - 7.8e-43 146.7 0.0 9.6e-43 146.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT00539.1 - 0.00016 21.6 0.0 0.00033 20.6 0.0 1.5 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 KXT00539.1 - 0.028 13.5 0.0 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.18 KXT00539.1 - 0.048 13.6 0.3 0.078 12.9 0.1 1.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 KXT00539.1 - 0.11 12.8 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain MFS_1 PF07690.16 KXT00540.1 - 6.2e-28 97.7 22.1 6.2e-28 97.7 22.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MCR_beta PF02241.18 KXT00540.1 - 0.077 12.6 0.3 0.14 11.7 0.3 1.3 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, C-terminal domain Ras PF00071.22 KXT00541.1 - 1.3e-40 138.7 0.0 1.6e-40 138.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXT00541.1 - 3.1e-12 46.8 0.0 5.7e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXT00541.1 - 3.5e-05 23.3 0.0 5.3e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family CWC25 PF12542.8 KXT00542.1 - 7.2e-24 84.6 0.1 7.2e-24 84.6 0.1 4.4 2 2 1 3 3 3 1 Pre-mRNA splicing factor Cir_N PF10197.9 KXT00542.1 - 1.4e-12 47.6 6.5 1.4e-12 47.6 6.5 4.5 4 1 1 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR 2-Hacid_dh_C PF02826.19 KXT00543.1 - 4.3e-51 172.8 0.1 6.6e-51 172.2 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXT00543.1 - 8.6e-11 41.6 0.0 1.3e-10 41.0 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KXT00543.1 - 7.1e-06 26.3 0.0 1.1e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.21 KXT00543.1 - 0.0066 15.8 0.0 0.022 14.1 0.0 1.7 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Poly_export PF02563.16 KXT00543.1 - 0.056 13.7 0.0 2.7 8.3 0.0 2.3 2 0 0 2 2 2 0 Polysaccharide biosynthesis/export protein HTH_1 PF00126.27 KXT00543.1 - 0.1 12.6 0.0 1.3 9.0 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family Nuc_deoxyrib_tr PF05014.15 KXT00544.1 - 7.3e-09 35.7 0.0 1.4e-08 34.8 0.0 1.5 2 0 0 2 2 2 1 Nucleoside 2-deoxyribosyltransferase Septin PF00735.18 KXT00545.1 - 6.8e-31 107.6 0.0 1.5e-17 63.8 0.0 3.1 2 1 0 2 2 2 2 Septin MMR_HSR1 PF01926.23 KXT00545.1 - 0.012 15.7 0.0 0.028 14.5 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 KXT00545.1 - 0.03 13.7 0.0 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Spem1 PF15670.5 KXT00545.1 - 0.038 13.6 0.2 0.038 13.6 0.2 3.3 2 2 0 2 2 2 0 Spermatid maturation protein 1 Roc PF08477.13 KXT00545.1 - 0.066 13.4 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DASH_Spc19 PF08287.11 KXT00546.1 - 3e-49 166.9 6.3 4.4e-49 166.4 6.3 1.3 1 0 0 1 1 1 1 Spc19 UPF0184 PF03670.13 KXT00546.1 - 0.02 15.3 1.9 0.046 14.1 0.0 2.2 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0184) COG5 PF10392.9 KXT00546.1 - 0.24 11.6 9.8 6.6 6.9 0.1 3.1 2 1 1 3 3 3 0 Golgi transport complex subunit 5 Spc7 PF08317.11 KXT00546.1 - 0.47 9.3 9.5 1.2 8.0 1.2 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Fib_alpha PF08702.10 KXT00546.1 - 1.2 9.3 6.0 10 6.3 0.0 2.9 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family COG2 PF06148.11 KXT00546.1 - 4.5 7.4 7.1 1.2 9.2 1.2 2.6 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Ras PF00071.22 KXT00547.1 - 5.6e-55 185.4 0.0 6.6e-55 185.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXT00547.1 - 2.1e-21 76.4 0.0 3.5e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXT00547.1 - 3.4e-08 33.2 0.0 4.5e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KXT00547.1 - 0.00092 18.8 0.1 0.0021 17.7 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Ribosomal_S27e PF01667.17 KXT00548.1 - 7.2e-29 99.3 6.8 9e-29 99.0 6.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 zf-C2HC5 PF06221.13 KXT00548.1 - 0.32 11.0 5.7 0.98 9.5 2.8 2.3 2 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type zf-CSL PF05207.13 KXT00548.1 - 0.45 10.3 3.3 1.3 8.8 3.3 1.7 1 1 0 1 1 1 0 CSL zinc finger DUF2076 PF09849.9 KXT00549.1 - 6.6e-10 39.5 13.0 8.3e-10 39.1 13.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 KXT00549.1 - 0.00012 22.1 2.0 0.0002 21.4 2.0 1.3 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 KXT00549.1 - 0.003 17.5 0.7 0.0054 16.7 0.7 1.3 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Med2 PF11214.8 KXT00549.1 - 0.17 12.1 0.0 0.24 11.6 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 2 YppG PF14179.6 KXT00549.1 - 3.4 8.4 13.0 4.6 8.0 8.6 2.2 2 0 0 2 2 2 0 YppG-like protein CorA PF01544.18 KXT00550.1 - 9.6e-11 41.5 0.0 3e-10 39.9 0.0 1.8 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Annexin PF00191.20 KXT00551.1 - 2.1e-24 85.4 3.7 5e-06 26.5 0.0 4.4 4 0 0 4 4 4 4 Annexin P-mevalo_kinase PF04275.14 KXT00551.1 - 0.34 10.9 3.2 3.1 7.8 0.6 2.6 2 0 0 2 2 2 0 Phosphomevalonate kinase FXMRP1_C_core PF12235.8 KXT00551.1 - 8 7.1 18.4 0.078 13.6 6.0 3.2 2 1 1 3 3 3 0 Fragile X-related 1 protein core C terminal UPF0139 PF03669.13 KXT00552.1 - 0.026 14.4 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0139) tRNA-synt_2 PF00152.20 KXT00553.1 - 4.2e-70 236.3 0.0 5.7e-70 235.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KXT00553.1 - 1.9e-05 24.6 0.0 3.4e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KXT00553.1 - 0.04 13.4 0.1 4.6 6.6 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Porin_5 PF16930.5 KXT00553.1 - 0.78 8.2 4.2 1.1 7.6 4.2 1.1 1 0 0 1 1 1 0 Putative porin SRP14 PF02290.15 KXT00553.1 - 2.4 8.6 4.5 56 4.2 3.7 2.7 2 1 1 3 3 3 0 Signal recognition particle 14kD protein Rogdi_lz PF10259.9 KXT00555.1 - 1.2e-88 297.1 0.0 1.4e-88 296.9 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein LIAS_N PF16881.5 KXT00556.1 - 1.9e-24 86.1 0.0 3.6e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 KXT00556.1 - 1.5e-15 58.0 0.0 2.4e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily G-patch PF01585.23 KXT00557.1 - 1.9e-06 27.7 3.3 4e-06 26.6 3.3 1.6 1 0 0 1 1 1 1 G-patch domain RED_N PF07808.13 KXT00557.1 - 0.0021 17.7 0.9 0.0021 17.7 0.9 2.3 3 0 0 3 3 3 1 RED-like protein N-terminal region RRM_1 PF00076.22 KXT00557.1 - 0.0023 17.7 0.0 0.0061 16.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.7 KXT00557.1 - 0.069 13.2 0.8 0.27 11.4 0.8 2.1 1 0 0 1 1 1 0 G-patch domain Sec2p PF06428.11 KXT00558.1 - 7.4e-29 99.6 13.6 7.4e-29 99.6 13.6 2.5 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p Tup_N PF08581.10 KXT00558.1 - 0.1 12.9 11.2 1 9.7 1.1 3.2 2 1 0 2 2 2 0 Tup N-terminal Prefoldin_2 PF01920.20 KXT00558.1 - 0.31 11.0 19.1 0.061 13.3 6.2 2.5 2 0 0 2 2 2 0 Prefoldin subunit DUF3584 PF12128.8 KXT00558.1 - 0.5 7.8 17.3 0.97 6.9 17.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) GCN5L1 PF06320.13 KXT00558.1 - 0.51 10.5 13.2 0.15 12.2 7.8 2.3 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) Jnk-SapK_ap_N PF09744.9 KXT00558.1 - 0.57 10.4 17.7 0.39 10.9 10.6 2.8 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF1664 PF07889.12 KXT00558.1 - 0.89 9.6 7.6 3.3 7.8 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) MHC2-interact PF09307.10 KXT00558.1 - 1.6 8.8 6.8 1.1 9.3 3.1 2.5 2 0 0 2 2 2 0 CLIP, MHC2 interacting ADIP PF11559.8 KXT00558.1 - 2.1 8.4 23.7 0.27 11.3 12.8 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF1043 PF06295.12 KXT00558.1 - 3.1 7.8 12.4 3.4 7.7 1.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Sec8_exocyst PF04048.14 KXT00558.1 - 3.7 7.4 9.3 15 5.4 0.3 2.3 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain EzrA PF06160.12 KXT00558.1 - 3.8 5.6 15.5 12 3.9 15.5 2.1 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Spc7 PF08317.11 KXT00558.1 - 6.2 5.6 24.2 5.2 5.9 5.6 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein Spc24 PF08286.11 KXT00558.1 - 6.2 7.1 17.8 3.6 7.9 3.5 3.1 1 1 0 2 2 2 0 Spc24 subunit of Ndc80 DUF5339 PF17274.2 KXT00558.1 - 7.1 7.6 15.7 0.44 11.4 0.9 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5339) TMF_TATA_bd PF12325.8 KXT00558.1 - 7.6 6.8 20.0 1.8 8.8 0.4 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding CC2-LZ PF16516.5 KXT00558.1 - 9.2 6.7 19.6 3.2 8.2 2.9 2.7 3 0 0 3 3 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator VIGSSK PF14773.6 KXT00559.1 - 0.019 15.1 0.5 0.026 14.6 0.5 1.2 1 0 0 1 1 1 0 Helicase-associated putative binding domain, C-terminal MF_alpha_N PF05436.11 KXT00559.1 - 0.032 14.1 0.0 0.051 13.5 0.0 1.3 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus Med12 PF09497.10 KXT00562.1 - 3.3e-26 91.3 0.2 8.3e-26 90.1 0.2 1.8 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.8 KXT00562.1 - 0.0016 17.4 0.0 0.003 16.5 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic Mediator 12 subunit domain DeoC PF01791.9 KXT00563.1 - 4.7e-15 55.8 0.0 8.1e-15 55.1 0.0 1.4 1 1 0 1 1 1 1 DeoC/LacD family aldolase DHO_dh PF01180.21 KXT00563.1 - 0.00034 19.9 0.1 0.00063 19.0 0.1 1.4 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NanE PF04131.14 KXT00563.1 - 0.0019 17.4 0.0 0.0049 16.1 0.0 1.6 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.21 KXT00563.1 - 0.0042 16.6 0.1 0.012 15.1 0.1 1.7 1 1 0 1 1 1 1 Histidine biosynthesis protein FMN_dh PF01070.18 KXT00563.1 - 0.061 12.4 0.6 0.12 11.3 0.3 1.5 2 0 0 2 2 2 0 FMN-dependent dehydrogenase TT_ORF2a PF08197.11 KXT00563.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 pORF2a truncated protein TP_methylase PF00590.20 KXT00565.1 - 1.1e-47 162.8 0.6 2.5e-47 161.6 0.1 1.9 2 1 1 3 3 3 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Sirohm_synth_C PF14823.6 KXT00565.1 - 2.2e-13 49.6 0.1 2.7e-09 36.5 0.0 2.5 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal NAD_binding_7 PF13241.6 KXT00565.1 - 2.5e-12 47.1 0.0 5.4e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.6 KXT00565.1 - 1.5e-10 40.3 2.0 1.9e-10 40.0 0.2 2.2 2 0 0 2 2 2 1 Sirohaem biosynthesis protein central PCI PF01399.27 KXT00566.1 - 4.1e-20 72.2 0.5 1.2e-19 70.8 0.1 2.0 2 0 0 2 2 2 1 PCI domain TPR_7 PF13176.6 KXT00566.1 - 0.00074 19.4 1.1 0.65 10.2 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KXT00566.1 - 0.00078 19.4 1.0 0.097 12.8 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat Sulfotransfer_1 PF00685.27 KXT00566.1 - 0.037 13.5 0.3 0.084 12.3 0.3 1.6 1 0 0 1 1 1 0 Sulfotransferase domain TPR_11 PF13414.6 KXT00566.1 - 0.11 12.2 0.4 0.59 9.9 0.1 2.5 2 0 0 2 2 2 0 TPR repeat TPR_1 PF00515.28 KXT00566.1 - 0.11 12.3 4.0 0.18 11.7 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXT00566.1 - 0.15 12.9 1.4 20 6.3 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat DctP PF03480.13 KXT00567.1 - 0.0023 17.3 0.5 0.005 16.2 0.1 1.7 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein, family 7 MoaE PF02391.17 KXT00568.1 - 4.5e-38 130.0 0.4 6.4e-38 129.5 0.4 1.2 1 0 0 1 1 1 1 MoaE protein ATP-sulfurylase PF01747.17 KXT00569.1 - 4.5e-88 294.2 0.0 6.2e-88 293.8 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 KXT00569.1 - 1.5e-56 190.7 0.1 2.2e-56 190.1 0.1 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 KXT00569.1 - 1.6e-52 177.4 0.0 3.1e-52 176.5 0.0 1.5 1 0 0 1 1 1 1 PUA-like domain ABC1 PF03109.16 KXT00570.1 - 5.2e-20 71.8 0.0 1.2e-19 70.7 0.0 1.6 1 0 0 1 1 1 1 ABC1 family FSAP_sig_propep PF03032.15 KXT00571.1 - 0.013 15.5 0.9 0.026 14.5 0.9 1.4 1 0 0 1 1 1 0 Frog skin active peptide family signal and propeptide DUF3481 PF11980.8 KXT00571.1 - 0.12 12.0 0.5 0.19 11.4 0.3 1.5 1 1 0 1 1 1 0 C-terminal domain of neuropilin glycoprotein Peptidase_C65 PF10275.9 KXT00572.1 - 6.1e-65 219.1 0.0 8.2e-65 218.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase C65 Otubain SUR7 PF06687.12 KXT00573.1 - 1.4e-34 119.6 12.8 2e-34 119.1 12.8 1.1 1 0 0 1 1 1 1 SUR7/PalI family PH_10 PF15411.6 KXT00573.1 - 0.068 13.4 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain Oxidored_q3 PF00499.20 KXT00573.1 - 0.38 10.5 12.8 1.4 8.7 9.5 2.3 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 E1-E2_ATPase PF00122.20 KXT00585.1 - 1.5e-47 161.5 2.2 2.8e-47 160.6 0.1 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KXT00585.1 - 1.9e-38 132.0 0.9 1.9e-38 132.0 0.9 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KXT00585.1 - 8.8e-22 78.4 2.5 4.3e-21 76.2 2.5 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXT00585.1 - 2.1e-17 62.6 0.0 3.9e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KXT00585.1 - 2.2e-14 53.3 0.0 4.3e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KXT00585.1 - 0.00012 21.9 1.2 0.00081 19.2 0.6 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXT00586.1 - 0.00052 20.4 0.0 0.0097 16.2 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KXT00586.1 - 0.14 12.2 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase PTR2 PF00854.21 KXT00588.1 - 4.6e-81 272.7 5.1 7.1e-81 272.0 5.1 1.3 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 KXT00588.1 - 4.9e-12 45.4 16.8 1.8e-11 43.6 15.5 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Holin_SPP1 PF04688.13 KXT00588.1 - 1 9.6 5.8 8.2 6.7 0.6 2.6 2 0 0 2 2 2 0 SPP1 phage holin MFS_1 PF07690.16 KXT00589.1 - 1.2e-34 119.8 25.9 1.2e-34 119.8 25.9 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily FAD_binding_3 PF01494.19 KXT00590.1 - 6.8e-21 74.9 0.0 1.9e-20 73.4 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXT00590.1 - 9.7e-05 22.5 0.0 0.00024 21.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXT00590.1 - 0.00011 21.9 0.2 0.0013 18.4 0.1 2.2 2 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXT00590.1 - 0.00022 20.6 0.0 0.00063 19.1 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXT00590.1 - 0.0085 15.2 0.1 0.015 14.4 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KXT00590.1 - 0.026 13.6 0.1 0.05 12.7 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 KXT00590.1 - 0.043 12.9 0.1 0.061 12.4 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.23 KXT00590.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.17 KXT00590.1 - 0.23 10.7 0.1 0.35 10.1 0.1 1.2 1 0 0 1 1 1 0 Thi4 family DDHD PF02862.17 KXT00592.1 - 7.4e-61 206.2 2.3 7.8e-60 202.8 0.0 2.7 2 1 0 2 2 2 1 DDHD domain DUF676 PF05057.14 KXT00592.1 - 0.055 13.0 0.1 0.14 11.6 0.0 1.7 2 0 0 2 2 2 0 Putative serine esterase (DUF676) LIDHydrolase PF10230.9 KXT00592.1 - 0.12 11.9 0.0 0.34 10.4 0.0 1.7 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase 4HBT PF03061.22 KXT00593.1 - 4.9e-10 39.6 0.1 8.1e-10 38.9 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Ribosomal_L44 PF00935.19 KXT00594.1 - 7.2e-37 125.7 12.6 1.1e-36 125.2 12.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 DIL PF01843.19 KXT00595.1 - 1.2e-31 109.1 1.4 2.6e-31 108.0 1.4 1.6 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.7 KXT00595.1 - 3.1e-16 59.7 0.0 9.6e-16 58.2 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXT00595.1 - 4.2e-13 49.5 0.2 2.4e-05 24.8 0.1 4.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXT00595.1 - 1.7e-11 44.1 0.5 2e-10 40.7 0.0 2.9 2 1 2 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 KXT00595.1 - 6e-11 42.3 0.3 4.7e-05 23.6 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KXT00595.1 - 1e-06 28.6 0.0 0.084 13.5 0.0 3.9 3 0 0 3 3 3 1 Ankyrin repeat Chorismate_synt PF01264.21 KXT00595.1 - 0.045 12.5 0.0 0.082 11.6 0.0 1.3 1 0 0 1 1 1 0 Chorismate synthase Allantoicase PF03561.15 KXT00596.1 - 9.4e-92 304.5 0.2 5.7e-47 159.3 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat Rad21_Rec8_N PF04825.13 KXT00597.1 - 6.2e-36 122.9 0.0 1.8e-35 121.5 0.0 1.8 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KXT00597.1 - 3.3e-07 29.5 0.0 7.8e-07 28.3 0.0 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ABM PF03992.16 KXT00598.1 - 3e-05 24.0 0.1 5.2e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF1876 PF08962.11 KXT00600.1 - 0.049 13.6 0.1 0.082 12.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1876) Cupin_1 PF00190.22 KXT00601.1 - 6.2e-05 22.7 0.0 7.4e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 KXT00601.1 - 0.012 15.3 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Cupin domain Aft1_HRA PF11786.8 KXT00601.1 - 0.029 14.7 0.0 0.058 13.7 0.0 1.5 1 0 0 1 1 1 0 Aft1 HRA domain DUF3748 PF12566.8 KXT00601.1 - 0.087 12.8 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3748) DUF4314 PF14192.6 KXT00601.1 - 0.2 11.6 0.0 0.39 10.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4314) Qua1 PF16274.5 KXT00603.1 - 0.16 11.8 2.7 0.32 10.9 2.7 1.5 1 0 0 1 1 1 0 Qua1 domain Fungal_trans PF04082.18 KXT00604.1 - 2.1e-08 33.6 0.2 3e-08 33.0 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1053 PF06327.14 KXT00604.1 - 0.12 13.0 0.0 0.22 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1053) Fungal_trans PF04082.18 KXT00605.1 - 2e-08 33.6 0.2 2.9e-08 33.1 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1053 PF06327.14 KXT00605.1 - 0.12 13.0 0.0 0.23 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1053) Fungal_trans PF04082.18 KXT00606.1 - 2.1e-08 33.6 0.2 3e-08 33.0 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1053 PF06327.14 KXT00606.1 - 0.12 13.0 0.0 0.22 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1053) Fungal_trans PF04082.18 KXT00607.1 - 2e-08 33.6 0.2 2.9e-08 33.1 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1053 PF06327.14 KXT00607.1 - 0.12 13.0 0.0 0.23 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1053) Sec23_trunk PF04811.15 KXT00608.1 - 1.5e-48 165.5 0.0 4.8e-48 163.8 0.0 1.7 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KXT00608.1 - 4.1e-24 84.4 0.0 7.8e-24 83.5 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KXT00608.1 - 6.3e-18 65.3 1.0 1.1e-17 64.5 1.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KXT00608.1 - 9.9e-16 57.5 3.6 2.2e-15 56.4 3.6 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KXT00608.1 - 9.7e-07 28.6 0.0 2.3e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Fungal_trans PF04082.18 KXT00609.1 - 2e-08 33.6 0.2 2.9e-08 33.1 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1053 PF06327.14 KXT00609.1 - 0.12 13.0 0.0 0.23 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1053) Sec23_trunk PF04811.15 KXT00610.1 - 1.5e-48 165.5 0.0 4.8e-48 163.8 0.0 1.7 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KXT00610.1 - 4.1e-24 84.4 0.0 7.8e-24 83.5 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KXT00610.1 - 6.3e-18 65.3 1.0 1.1e-17 64.5 1.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KXT00610.1 - 9.9e-16 57.5 3.6 2.2e-15 56.4 3.6 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KXT00610.1 - 9.7e-07 28.6 0.0 2.3e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Zn_clus PF00172.18 KXT00611.1 - 5.6e-06 26.4 13.0 5.6e-06 26.4 13.0 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Vps39_2 PF10367.9 KXT00611.1 - 0.28 11.6 2.3 0.53 10.8 2.3 1.4 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 Sec23_trunk PF04811.15 KXT00612.1 - 1.5e-48 165.5 0.0 4.8e-48 163.8 0.0 1.7 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KXT00612.1 - 4.1e-24 84.4 0.0 7.8e-24 83.5 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KXT00612.1 - 6.3e-18 65.3 1.0 1.1e-17 64.5 1.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KXT00612.1 - 9.9e-16 57.5 3.6 2.2e-15 56.4 3.6 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KXT00612.1 - 9.7e-07 28.6 0.0 2.3e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat RasGEF PF00617.19 KXT00613.1 - 3.7e-46 157.6 0.3 6.2e-46 156.8 0.3 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KXT00613.1 - 3.1e-12 46.7 0.1 6.5e-12 45.6 0.1 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif CorA PF01544.18 KXT00614.1 - 4.3e-42 144.4 0.1 2.6e-20 72.9 0.5 2.3 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein CYSTM PF12734.7 KXT00615.1 - 0.00012 22.3 65.2 0.8 10.1 50.5 3.7 2 1 0 2 2 2 2 Cysteine-rich TM module stress tolerance MSC PF09402.10 KXT00616.1 - 1.3e-105 353.6 0.0 2.1e-105 352.9 0.0 1.3 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 KXT00616.1 - 2.6e-17 62.2 0.0 5.8e-17 61.1 0.0 1.7 1 0 0 1 1 1 1 HeH/LEM domain Thymopoietin PF08198.11 KXT00616.1 - 4.7e-06 26.1 0.0 9.1e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Thymopoietin protein CAP PF00188.26 KXT00618.1 - 1.7e-14 54.7 4.0 2.3e-14 54.3 4.0 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family KilA-N PF04383.13 KXT00619.1 - 4.9e-05 23.1 0.0 0.00089 19.1 0.0 2.2 1 1 0 1 1 1 1 KilA-N domain FRQ PF09421.10 KXT00620.1 - 1.3e-128 430.7 56.1 4.9e-128 428.7 54.1 2.4 1 1 0 1 1 1 1 Frequency clock protein Pkinase PF00069.25 KXT00621.1 - 6.1e-28 97.9 0.0 3.6e-26 92.1 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT00621.1 - 1.7e-13 50.5 0.0 1.6e-12 47.3 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KXT00621.1 - 0.0015 17.5 0.0 0.0022 17.0 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KXT00621.1 - 0.0018 18.2 0.1 0.0035 17.3 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KXT00621.1 - 0.041 12.9 0.0 0.06 12.3 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF4140 PF13600.6 KXT00621.1 - 0.063 13.7 0.1 0.26 11.7 0.0 2.0 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Exo_endo_phos PF03372.23 KXT00623.1 - 1.1e-10 41.4 0.0 2.1e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SLAC1 PF03595.17 KXT00624.1 - 3.9e-58 197.3 42.9 4.4e-58 197.1 42.9 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel ArsB PF02040.15 KXT00626.1 - 2.2e-15 56.9 23.6 1.1e-08 34.9 6.7 2.1 2 0 0 2 2 2 2 Arsenical pump membrane protein CitMHS PF03600.16 KXT00626.1 - 9.3e-12 44.7 16.2 9.3e-12 44.7 16.2 1.8 1 1 0 1 1 1 1 Citrate transporter zf-RING_2 PF13639.6 KXT00626.1 - 0.0031 17.8 0.4 0.0031 17.8 0.4 1.9 2 0 0 2 2 2 1 Ring finger domain SKG6 PF08693.10 KXT00626.1 - 1.9 7.9 5.2 8.7 5.9 5.2 2.2 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PBP1_TM PF14812.6 KXT00626.1 - 3.9 7.9 12.8 34 4.9 0.0 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Stealth_CR3 PF17102.5 KXT00627.1 - 3.3 7.7 5.6 3.5 7.6 0.1 3.2 3 0 0 3 3 3 0 Stealth protein CR3, conserved region 3 hnRNP_Q_AcD PF18360.1 KXT00628.1 - 0.21 11.6 0.0 0.62 10.1 0.0 1.8 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain PHO4 PF01384.20 KXT00631.1 - 1.1e-102 343.6 18.0 1.2e-102 343.4 18.0 1.0 1 0 0 1 1 1 1 Phosphate transporter family HATPase_c PF02518.26 KXT00632.1 - 5.2e-33 113.9 0.0 1.3e-32 112.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXT00632.1 - 2.7e-21 75.8 0.0 8.3e-21 74.3 0.0 1.9 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KXT00632.1 - 1.8e-19 69.5 1.0 5.7e-19 67.9 0.0 2.5 2 0 0 2 2 1 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.6 KXT00632.1 - 9.8e-18 65.1 0.0 2e-16 60.8 0.0 3.2 2 0 0 2 2 2 1 AAA ATPase domain GAF_2 PF13185.6 KXT00632.1 - 2.5e-10 40.8 0.0 6.9e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.25 KXT00632.1 - 2.4e-08 33.7 0.0 4.8e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain GAF PF01590.26 KXT00632.1 - 9.5e-08 32.8 0.0 2.9e-07 31.2 0.0 1.9 1 0 0 1 1 1 1 GAF domain Pkinase_Tyr PF07714.17 KXT00632.1 - 1.4e-06 27.8 0.0 2.9e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_12 PF13424.6 KXT00632.1 - 0.00014 22.1 3.1 0.045 14.0 0.4 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat HATPase_c_3 PF13589.6 KXT00632.1 - 0.00064 19.6 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NACHT PF05729.12 KXT00632.1 - 0.0008 19.4 0.0 1.8 8.5 0.0 2.9 2 0 0 2 2 2 2 NACHT domain AAA_22 PF13401.6 KXT00632.1 - 0.01 16.1 0.0 0.15 12.3 0.0 2.8 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KXT00632.1 - 0.014 14.6 0.0 0.035 13.3 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain GAF_3 PF13492.6 KXT00632.1 - 0.019 15.3 0.0 0.044 14.1 0.0 1.7 1 0 0 1 1 1 0 GAF domain ANAPC3 PF12895.7 KXT00632.1 - 0.021 15.0 0.6 1.3 9.3 0.0 3.1 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 KXT00632.1 - 0.04 13.6 0.2 0.04 13.6 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain MeaB PF03308.16 KXT00632.1 - 0.058 12.4 1.4 0.063 12.2 0.0 1.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB GlnD_UR_UTase PF08335.11 KXT00632.1 - 0.085 12.9 0.0 0.63 10.1 0.0 2.4 2 0 0 2 2 2 0 GlnD PII-uridylyltransferase TPR_2 PF07719.17 KXT00632.1 - 0.4 10.9 5.6 35 4.8 0.2 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXT00632.1 - 0.61 10.0 2.8 63 3.6 0.4 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXT00632.1 - 6.1 7.9 15.9 1.4 9.9 0.1 5.7 5 1 1 6 6 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KXT00632.1 - 6.2 7.5 8.5 2.8 8.7 0.1 3.6 4 0 0 4 4 2 0 Tetratricopeptide repeat Sugar_tr PF00083.24 KXT00633.1 - 1.1e-78 265.2 20.2 1.8e-78 264.4 20.2 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXT00633.1 - 5.7e-24 84.7 54.0 4.1e-16 58.8 30.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ADH_N PF08240.12 KXT00633.1 - 0.00011 22.0 0.0 0.00023 21.0 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXT00633.1 - 0.00037 20.5 0.0 0.0042 17.1 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase HNH_2 PF13391.6 KXT00641.1 - 4.7e-09 36.2 0.1 1.6e-08 34.6 0.1 1.9 1 0 0 1 1 1 1 HNH endonuclease SVA PF05326.11 KXT00642.1 - 0.06 13.3 0.1 0.089 12.8 0.1 1.2 1 0 0 1 1 1 0 Seminal vesicle autoantigen (SVA) CwsA PF10814.8 KXT00642.1 - 1 9.6 5.2 0.94 9.6 3.8 1.7 1 1 1 2 2 2 0 Cell wall synthesis protein CwsA rRNA_methylase PF06962.12 KXT00644.1 - 0.047 13.7 0.0 0.08 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative rRNA methylase PHP_C PF13263.6 KXT00646.1 - 0.072 12.9 0.1 28 4.6 0.0 3.5 3 0 0 3 3 3 0 PHP-associated ATG16 PF08614.11 KXT00647.1 - 4.1e-05 23.9 12.6 5.1e-05 23.6 12.6 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) APG6_N PF17675.1 KXT00647.1 - 0.0007 20.1 15.9 0.0007 20.1 15.9 1.3 1 1 0 1 1 1 1 Apg6 coiled-coil region KELK PF15796.5 KXT00647.1 - 0.0047 17.4 10.4 0.0078 16.6 10.4 1.4 1 0 0 1 1 1 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase Fez1 PF06818.15 KXT00647.1 - 0.005 17.3 10.1 0.0061 17.0 10.1 1.1 1 0 0 1 1 1 1 Fez1 HMMR_N PF15905.5 KXT00647.1 - 0.019 14.5 12.1 0.025 14.0 12.1 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Laminin_II PF06009.12 KXT00647.1 - 0.022 14.8 4.2 0.026 14.5 4.2 1.2 1 0 0 1 1 1 0 Laminin Domain II Med4 PF10018.9 KXT00647.1 - 0.025 14.2 5.5 0.037 13.7 5.5 1.4 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF3891 PF13030.6 KXT00647.1 - 0.026 14.3 1.4 0.03 14.1 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3891) bZIP_1 PF00170.21 KXT00647.1 - 0.036 14.2 2.1 0.036 14.2 2.1 2.3 1 1 1 2 2 2 0 bZIP transcription factor DUF745 PF05335.13 KXT00647.1 - 0.044 13.5 11.9 0.071 12.8 11.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF745) GAS PF13851.6 KXT00647.1 - 0.06 12.7 15.7 0.22 10.8 15.7 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DAPDH_C PF16654.5 KXT00647.1 - 0.07 13.0 1.2 0.11 12.3 1.0 1.4 1 1 0 1 1 1 0 Diaminopimelic acid dehydrogenase C-terminal domain ADIP PF11559.8 KXT00647.1 - 0.07 13.2 15.1 0.18 11.9 14.7 1.9 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding TMPIT PF07851.13 KXT00647.1 - 0.071 12.3 5.7 0.084 12.1 5.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein ERM PF00769.19 KXT00647.1 - 0.073 12.9 14.7 0.084 12.7 14.7 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF3450 PF11932.8 KXT00647.1 - 0.1 11.9 11.4 0.13 11.5 11.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) AAA_13 PF13166.6 KXT00647.1 - 0.12 11.0 10.9 0.15 10.6 10.9 1.1 1 0 0 1 1 1 0 AAA domain NBP1 PF08537.10 KXT00647.1 - 0.13 11.7 5.9 0.15 11.5 5.9 1.2 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 CENP-H PF05837.12 KXT00647.1 - 0.13 12.7 8.4 0.19 12.1 8.4 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Uso1_p115_C PF04871.13 KXT00647.1 - 0.13 12.6 9.1 0.18 12.2 9.1 1.4 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region TMF_DNA_bd PF12329.8 KXT00647.1 - 0.15 12.1 11.0 0.66 10.0 10.6 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Atg14 PF10186.9 KXT00647.1 - 0.16 11.0 10.9 0.18 10.9 10.9 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4874 PF16173.5 KXT00647.1 - 0.17 11.6 3.5 0.3 10.8 3.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4874) Tropomyosin_1 PF12718.7 KXT00647.1 - 0.21 11.7 14.9 0.11 12.7 5.5 2.2 1 1 0 1 1 1 0 Tropomyosin like GCN5L1 PF06320.13 KXT00647.1 - 0.26 11.4 9.6 0.42 10.8 8.8 1.7 1 1 1 2 2 2 0 GCN5-like protein 1 (GCN5L1) DUF5595 PF18077.1 KXT00647.1 - 0.32 11.1 6.4 0.77 9.9 1.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5595) HAUS6_N PF14661.6 KXT00647.1 - 0.34 10.4 8.0 0.44 10.1 8.0 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF16 PF01519.16 KXT00647.1 - 0.38 11.3 9.8 0.66 10.5 9.1 1.7 1 1 1 2 2 2 0 Protein of unknown function DUF16 Methyltransf_1N PF02870.15 KXT00647.1 - 0.5 11.2 2.7 0.5 11.2 1.0 1.7 1 1 1 2 2 2 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain PHM7_cyt PF14703.6 KXT00647.1 - 0.58 10.4 6.5 0.5 10.6 5.7 1.4 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter DUF1664 PF07889.12 KXT00647.1 - 0.65 10.0 5.2 4.9 7.2 3.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF1515 PF07439.11 KXT00647.1 - 0.84 9.7 4.9 0.59 10.2 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) UPF0242 PF06785.11 KXT00647.1 - 0.9 9.6 13.6 1.1 9.3 13.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Exonuc_VII_L PF02601.15 KXT00647.1 - 0.92 9.0 9.5 1.1 8.8 9.5 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Prefoldin_2 PF01920.20 KXT00647.1 - 1.2 9.2 16.1 0.54 10.2 4.2 2.2 1 1 1 2 2 2 0 Prefoldin subunit DUF724 PF05266.14 KXT00647.1 - 1.3 8.9 9.5 1.7 8.5 9.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) SlyX PF04102.12 KXT00647.1 - 1.3 9.7 15.5 0.32 11.6 2.1 2.3 1 1 1 2 2 2 0 SlyX Prominin PF05478.11 KXT00647.1 - 1.4 6.8 7.4 1.5 6.7 7.4 1.0 1 0 0 1 1 1 0 Prominin Seryl_tRNA_N PF02403.22 KXT00647.1 - 1.6 9.0 11.1 2.7 8.2 10.3 1.9 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Fib_alpha PF08702.10 KXT00647.1 - 1.6 8.9 10.3 3.7 7.7 8.8 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.11 KXT00647.1 - 1.8 9.0 5.9 0.62 10.5 1.0 2.1 1 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Swi5 PF07061.11 KXT00647.1 - 2.4 8.3 12.7 2.3 8.4 1.0 2.4 1 1 1 2 2 2 0 Swi5 OmpH PF03938.14 KXT00647.1 - 2.4 8.5 17.8 3.1 8.1 17.3 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.6 KXT00647.1 - 3.8 6.8 12.8 4.8 6.4 12.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 KXT00647.1 - 5.6 6.8 21.0 0.18 11.6 3.8 2.9 1 1 2 3 3 3 0 Septum formation initiator RskA PF10099.9 KXT00652.1 - 0.02 15.2 0.0 0.023 15.0 0.0 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF4381 PF14316.6 KXT00652.1 - 0.031 14.5 0.0 0.046 14.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Trp_oprn_chp PF09534.10 KXT00652.1 - 0.055 13.3 0.0 0.067 13.0 0.0 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF2207 PF09972.9 KXT00652.1 - 0.066 12.0 0.0 0.076 11.8 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Phage_holin_2_4 PF16082.5 KXT00652.1 - 0.11 12.3 0.9 0.13 12.0 0.0 1.6 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like DNA_methylase PF00145.17 KXT00652.1 - 0.12 11.6 0.1 0.15 11.4 0.1 1.1 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase DUF5305 PF17231.2 KXT00652.1 - 0.17 11.3 0.0 0.2 11.0 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) CDC45 PF02724.14 KXT00657.1 - 0.038 12.3 7.7 0.05 11.9 7.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Sin_N PF04801.13 KXT00657.1 - 0.29 10.3 7.8 0.38 9.9 7.8 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region RR_TM4-6 PF06459.12 KXT00657.1 - 2.1 8.1 9.3 2.7 7.7 9.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hid1 PF12722.7 KXT00657.1 - 2.5 6.1 6.1 3.2 5.7 6.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.16 KXT00657.1 - 3.4 7.6 4.4 4.8 7.2 4.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 KXT00657.1 - 4.4 6.0 7.0 5.9 5.5 7.0 1.1 1 0 0 1 1 1 0 Presenilin RP-C_C PF11800.8 KXT00659.1 - 0.01 16.0 1.5 0.088 12.9 0.3 2.0 2 0 0 2 2 2 0 Replication protein C C-terminal region HTH_AsnC-type PF13404.6 KXT00659.1 - 0.017 14.9 1.2 0.039 13.8 0.9 1.9 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 KXT00659.1 - 0.1 12.1 0.0 0.38 10.3 0.1 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Phage_holin_3_3 PF16083.5 KXT00666.1 - 0.095 12.8 3.1 0.34 11.0 0.1 2.4 3 0 0 3 3 3 0 LydA holin phage, holin superfamily III PRIMA1 PF16101.5 KXT00666.1 - 0.29 11.2 8.0 0.061 13.4 4.1 1.8 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 DUF5518 PF17647.1 KXT00666.1 - 0.65 10.2 8.5 1.7 8.8 0.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5518) Ank_4 PF13637.6 KXT00677.1 - 4.9e-12 46.1 0.1 2.3e-06 28.0 0.0 2.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXT00677.1 - 7.5e-12 45.7 0.0 1.1e-05 26.0 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXT00677.1 - 6e-10 39.2 0.1 0.00025 21.3 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KXT00677.1 - 6.3e-10 39.0 0.1 0.0013 19.1 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 KXT00677.1 - 4.3e-09 35.9 0.1 0.0044 17.4 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat KilA-N PF04383.13 KXT00677.1 - 2.3e-05 24.2 1.4 6.5e-05 22.7 0.2 2.3 2 1 0 2 2 2 1 KilA-N domain PQ-loop PF04193.14 KXT00678.1 - 9.4e-18 63.7 15.6 7e-15 54.6 0.9 3.8 3 1 0 3 3 3 2 PQ loop repeat LtrA PF06772.11 KXT00678.1 - 0.0032 16.7 0.7 0.0048 16.2 0.7 1.2 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) EamA PF00892.20 KXT00678.1 - 2.6 8.2 8.0 0.96 9.6 1.0 2.3 2 0 0 2 2 2 0 EamA-like transporter family PQ-loop PF04193.14 KXT00679.1 - 2.9e-23 81.4 13.7 7.8e-15 54.4 0.9 3.3 3 0 0 3 3 3 2 PQ loop repeat DPM3 PF08285.11 KXT00679.1 - 0.14 12.4 0.5 0.54 10.5 0.5 2.0 1 0 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Pkinase PF00069.25 KXT00680.1 - 9.8e-44 149.7 0.0 1.8e-43 148.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT00680.1 - 8.7e-18 64.5 0.0 1.7e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXT00680.1 - 0.011 15.7 2.2 1.7 8.5 0.1 3.3 2 1 0 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.22 KXT00680.1 - 0.017 14.7 0.3 0.043 13.4 0.1 1.7 1 1 1 2 2 2 0 RIO1 family Kdo PF06293.14 KXT00680.1 - 0.023 14.0 0.2 0.043 13.2 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HCMVantigenic_N PF12154.8 KXT00680.1 - 0.048 13.8 0.7 0.048 13.8 0.7 3.5 4 0 0 4 4 4 0 Glycoprotein B N-terminal antigenic domain of HCMV Kinase-like PF14531.6 KXT00680.1 - 0.062 12.6 0.1 0.2 10.9 0.0 1.9 2 1 0 2 2 2 0 Kinase-like ZZ PF00569.17 KXT00681.1 - 8.1e-13 48.0 7.0 1.5e-12 47.1 7.0 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_1 PF00036.32 KXT00681.1 - 3.6e-11 41.8 1.3 0.00013 21.2 0.5 2.9 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KXT00681.1 - 4.7e-07 29.2 3.6 0.0046 16.8 0.1 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 KXT00681.1 - 1.9e-06 28.2 0.4 0.028 14.9 0.1 3.6 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 KXT00681.1 - 0.00017 21.4 0.5 0.32 10.9 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KXT00681.1 - 0.0021 17.4 4.0 0.11 12.0 0.1 2.8 3 0 0 3 3 3 2 EF hand Dockerin_1 PF00404.18 KXT00681.1 - 0.066 13.4 0.5 0.51 10.6 0.1 2.5 2 0 0 2 2 2 0 Dockerin type I domain Vps5 PF09325.10 KXT00682.1 - 5.4e-83 278.2 2.7 5.4e-83 278.2 2.7 1.8 2 0 0 2 2 2 1 Vps5 C terminal like SUI1 PF01253.22 KXT00682.1 - 1.1e-25 90.0 0.1 2.3e-25 88.9 0.1 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 PX PF00787.24 KXT00682.1 - 1.7e-24 86.0 0.0 4.5e-24 84.6 0.0 1.8 1 0 0 1 1 1 1 PX domain KELK PF15796.5 KXT00682.1 - 0.016 15.7 0.8 0.016 15.7 0.8 3.2 4 0 0 4 4 4 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Sec34 PF04136.15 KXT00682.1 - 0.076 12.9 1.0 5.6 6.8 0.1 2.6 2 0 0 2 2 2 0 Sec34-like family NAD_binding_8 PF13450.6 KXT00683.1 - 1.7e-12 47.4 0.6 4.7e-12 46.0 0.6 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KXT00683.1 - 9.9e-09 35.0 0.2 4.9e-07 29.4 0.2 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 KXT00683.1 - 7.3e-06 24.9 0.3 1e-05 24.4 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 KXT00683.1 - 9.1e-06 25.0 0.5 1.5e-05 24.3 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXT00683.1 - 1e-05 25.3 0.1 1.7e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KXT00683.1 - 1.2e-05 24.9 1.4 2e-05 24.2 1.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KXT00683.1 - 9.1e-05 21.9 0.3 0.00013 21.3 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KXT00683.1 - 0.00069 18.9 0.4 0.0013 18.0 0.4 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KXT00683.1 - 0.0013 18.0 0.2 0.0021 17.4 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXT00683.1 - 0.0025 17.0 0.5 0.0036 16.4 0.5 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KXT00683.1 - 0.0033 16.7 0.1 0.0069 15.7 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXT00683.1 - 0.013 14.6 0.5 0.022 13.8 0.1 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 KXT00683.1 - 0.04 13.9 0.2 0.11 12.5 0.1 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 KXT00683.1 - 0.056 14.0 0.2 0.12 13.0 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KXT00683.1 - 0.15 11.7 0.6 0.31 10.7 0.6 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Ribosomal_L5e PF17144.4 KXT00684.1 - 7.7e-77 256.9 0.1 7.7e-77 256.9 0.1 1.5 2 0 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 KXT00684.1 - 4.7e-35 120.4 8.7 4.7e-35 120.4 8.7 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Ribosomal_L18p PF00861.22 KXT00684.1 - 0.004 17.5 2.6 0.025 15.0 0.0 2.3 2 0 0 2 2 2 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Thr_synth_N PF14821.6 KXT00684.1 - 0.02 15.1 0.2 0.44 10.8 0.0 2.7 3 0 0 3 3 3 0 Threonine synthase N terminus BRCT PF00533.26 KXT00685.1 - 1.1e-05 25.7 0.2 4e-05 23.9 0.1 2.0 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KXT00685.1 - 0.0058 16.5 0.2 0.043 13.8 0.0 2.6 3 0 0 3 3 3 1 twin BRCT domain DUF5416 PF17437.2 KXT00685.1 - 0.051 13.4 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5416) BRCT_2 PF16589.5 KXT00685.1 - 0.07 13.5 0.2 0.16 12.4 0.2 1.5 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain UIM PF02809.20 KXT00686.1 - 0.00012 21.7 3.5 0.00029 20.6 3.5 1.7 1 0 0 1 1 1 1 Ubiquitin interaction motif F-box-like PF12937.7 KXT00687.1 - 0.0044 16.9 0.8 1.1 9.3 0.3 2.6 2 0 0 2 2 2 2 F-box-like Serglycin PF04360.12 KXT00688.1 - 0.0079 16.2 1.0 0.013 15.5 1.0 1.4 1 0 0 1 1 1 1 Serglycin SPX PF03105.19 KXT00688.1 - 1.1 9.1 10.9 1.3 8.9 10.9 1.1 1 0 0 1 1 1 0 SPX domain DUF4719 PF15843.5 KXT00688.1 - 1.9 8.6 7.2 3.2 7.8 7.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) LRR_6 PF13516.6 KXT00689.1 - 2.7 8.3 7.3 21 5.5 0.8 5.1 6 0 0 6 6 6 0 Leucine Rich repeat LAP1C PF05609.12 KXT00689.1 - 4.7 6.2 9.6 14 4.7 9.6 1.7 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) IGPS PF00218.21 KXT00690.1 - 4e-95 317.8 0.1 8e-95 316.8 0.0 1.6 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase GATase PF00117.28 KXT00690.1 - 9.4e-46 156.0 0.0 1.7e-45 155.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I PRAI PF00697.22 KXT00690.1 - 1.7e-45 155.2 0.4 8.9e-41 139.8 0.1 2.3 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Peptidase_C26 PF07722.13 KXT00690.1 - 0.00017 21.4 0.1 0.00063 19.5 0.1 1.9 1 1 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.19 KXT00690.1 - 0.13 12.0 2.4 0.84 9.4 0.1 2.9 3 0 0 3 3 3 0 Quinolinate phosphoribosyl transferase, C-terminal domain STT3 PF02516.14 KXT00691.1 - 5.9e-141 470.7 30.5 3.3e-137 458.4 28.4 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Dpy19 PF10034.9 KXT00691.1 - 0.22 9.7 2.6 1 7.5 2.6 2.1 1 1 0 1 1 1 0 Q-cell neuroblast polarisation DUF4244 PF14029.6 KXT00691.1 - 4.7 6.7 5.7 3.6 7.1 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4244) PEMT PF04191.13 KXT00694.1 - 2.1e-33 114.9 2.0 3.5e-33 114.2 2.0 1.4 1 0 0 1 1 1 1 Phospholipid methyltransferase Aa_trans PF01490.18 KXT00695.1 - 1.1e-26 93.5 37.6 1.3e-26 93.3 37.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF4231 PF14015.6 KXT00695.1 - 4.2 7.9 12.2 0.67 10.5 0.7 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF4231) zf-HC5HC2H_2 PF13832.6 KXT00696.1 - 2.2e-32 111.5 6.4 2.2e-32 111.5 6.4 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.9 KXT00696.1 - 7.2e-30 104.4 0.9 1.8e-29 103.2 0.0 2.2 2 0 0 2 2 2 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.6 KXT00696.1 - 6.9e-27 93.5 4.5 6.9e-27 93.5 4.5 2.6 2 1 0 2 2 2 1 PHD-like zinc-binding domain PHD_2 PF13831.6 KXT00696.1 - 1e-13 50.6 1.3 1e-13 50.6 1.3 2.0 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 KXT00696.1 - 3e-10 39.8 22.6 2.9e-09 36.7 9.6 2.5 2 0 0 2 2 2 2 PHD-finger Bromodomain PF00439.25 KXT00696.1 - 0.14 12.3 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 Bromodomain zf-RING-like PF08746.11 KXT00696.1 - 9.9 6.6 20.5 0.11 12.9 6.4 2.6 2 1 0 2 2 2 0 RING-like domain Sugar_tr PF00083.24 KXT00697.1 - 1.8e-27 96.3 22.8 6.4e-25 87.9 22.8 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter Acetyltransf_10 PF13673.7 KXT00698.1 - 1.1e-11 44.8 0.0 1.9e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXT00698.1 - 1.4e-10 41.4 0.0 2.8e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXT00698.1 - 1.9e-08 34.6 0.0 3.7e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXT00698.1 - 4.2e-05 23.6 0.1 0.00011 22.3 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXT00698.1 - 0.015 15.2 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Sugar_tr PF00083.24 KXT00699.1 - 1.4e-79 268.1 23.6 1.9e-79 267.7 23.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXT00699.1 - 1.9e-26 92.9 36.2 9.1e-26 90.6 35.9 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KXT00699.1 - 1.9e-06 26.6 2.5 3.2e-06 25.9 2.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ApbA PF02558.16 KXT00700.1 - 1.6e-25 89.5 0.0 2.4e-25 89.0 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KXT00700.1 - 7e-22 78.0 0.0 1e-21 77.4 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Cupin_8 PF13621.6 KXT00703.1 - 4.7e-24 85.5 0.0 6.3e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.11 KXT00703.1 - 0.0034 17.0 0.0 0.011 15.5 0.1 1.8 2 0 0 2 2 2 1 Cupin domain Cupin_4 PF08007.12 KXT00703.1 - 0.02 14.4 0.0 0.043 13.3 0.0 1.5 1 0 0 1 1 1 0 Cupin superfamily protein JmjC PF02373.22 KXT00703.1 - 0.11 13.0 0.0 0.54 10.7 0.0 2.1 3 0 0 3 3 3 0 JmjC domain, hydroxylase Proteasom_Rpn13 PF04683.13 KXT00704.1 - 1.1e-28 99.5 0.0 2e-28 98.8 0.0 1.4 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 KXT00704.1 - 1.7e-09 37.8 3.2 9.6e-08 32.2 3.2 2.3 1 1 0 1 1 1 1 UCH-binding domain Proteasom_Rpn13 PF04683.13 KXT00705.1 - 1.1e-28 99.5 0.0 2e-28 98.8 0.0 1.4 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 KXT00705.1 - 1.7e-09 37.8 3.2 9.6e-08 32.2 3.2 2.3 1 1 0 1 1 1 1 UCH-binding domain SKG6 PF08693.10 KXT00706.1 - 0.00047 19.5 1.7 0.0012 18.3 1.7 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain MLANA PF14991.6 KXT00706.1 - 0.0028 17.9 0.0 0.004 17.4 0.0 1.3 1 0 0 1 1 1 1 Protein melan-A Herpes_gE PF02480.16 KXT00706.1 - 0.012 14.4 0.0 0.016 14.0 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Phage_holin_2_1 PF04971.12 KXT00706.1 - 0.039 14.0 0.1 0.065 13.3 0.1 1.4 1 0 0 1 1 1 0 Bacteriophage P21 holin S EphA2_TM PF14575.6 KXT00706.1 - 0.052 14.4 0.0 0.089 13.7 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4328 PF14219.6 KXT00706.1 - 0.056 13.0 0.2 0.082 12.5 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) DUF4381 PF14316.6 KXT00706.1 - 0.056 13.7 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Beta-APP PF03494.13 KXT00706.1 - 0.067 13.1 2.2 0.11 12.3 2.2 1.3 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) CorA PF01544.18 KXT00707.1 - 4.4e-12 45.9 0.1 6e-12 45.5 0.1 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2207 PF09972.9 KXT00707.1 - 0.016 14.0 0.1 0.025 13.3 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Metallophos PF00149.28 KXT00708.1 - 8.9e-36 124.3 0.1 1.4e-35 123.7 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KXT00708.1 - 3.2e-17 62.7 0.0 5.5e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain TFIIA PF03153.13 KXT00709.1 - 0.011 15.7 24.2 0.022 14.8 24.2 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAN_4 PF14295.6 KXT00710.1 - 1.2e-12 47.5 38.0 5.7e-05 22.9 0.3 7.2 7 0 0 7 7 7 5 PAN domain Robl_LC7 PF03259.17 KXT00711.1 - 2.4e-07 30.4 0.2 0.00033 20.4 0.0 2.1 2 0 0 2 2 2 2 Roadblock/LC7 domain Biotin_lipoyl PF00364.22 KXT00712.1 - 2e-20 72.4 0.6 1.2e-19 69.8 0.4 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 KXT00712.1 - 6.2e-08 32.9 0.0 6.2e-08 32.9 0.0 2.1 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 KXT00712.1 - 0.00054 19.7 0.0 0.0065 16.3 0.0 2.5 2 0 0 2 2 2 1 Biotin-lipoyl like Spt20 PF12090.8 KXT00712.1 - 0.0094 15.6 1.1 0.015 15.0 1.1 1.2 1 0 0 1 1 1 1 Spt20 family QRPTase_N PF02749.16 KXT00712.1 - 0.15 12.1 0.0 0.91 9.6 0.0 2.3 2 1 1 3 3 3 0 Quinolinate phosphoribosyl transferase, N-terminal domain UbiA PF01040.18 KXT00713.1 - 3.9e-57 193.4 14.9 3.9e-57 193.4 14.9 1.6 1 1 1 2 2 2 1 UbiA prenyltransferase family TauD PF02668.16 KXT00715.1 - 3.8e-47 161.3 2.5 3.6e-46 158.1 2.5 2.2 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KXT00715.1 - 0.0021 18.6 0.0 0.0048 17.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF971) DUF2379 PF09543.10 KXT00715.1 - 0.069 13.4 0.2 0.38 10.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2379) PIR PF00399.19 KXT00716.1 - 5.1e-06 25.9 5.5 5.1e-06 25.9 5.5 2.8 3 0 0 3 3 3 1 Yeast PIR protein repeat NDUF_B7 PF05676.13 KXT00717.1 - 8.2e-30 102.3 5.1 1e-29 102.0 5.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) BSP_II PF05432.11 KXT00718.1 - 3.3 7.3 6.7 4.7 6.8 6.7 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Hydrolase_4 PF12146.8 KXT00719.1 - 4.9e-46 156.9 0.0 6.1e-46 156.6 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXT00719.1 - 5.5e-11 43.5 0.0 7e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXT00719.1 - 9.9e-10 38.5 0.0 2.1e-09 37.4 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF1749 PF08538.10 KXT00719.1 - 0.00079 18.6 0.0 0.0014 17.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Esterase PF00756.20 KXT00719.1 - 0.0016 18.2 0.0 0.0043 16.7 0.0 1.7 1 1 0 1 1 1 1 Putative esterase DLH PF01738.18 KXT00719.1 - 0.0042 16.7 0.0 0.15 11.6 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family PAF-AH_p_II PF03403.13 KXT00719.1 - 0.029 12.9 0.2 0.55 8.7 0.0 2.1 1 1 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II PGAP1 PF07819.13 KXT00719.1 - 0.031 14.0 0.0 0.047 13.4 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Chlorophyllase2 PF12740.7 KXT00719.1 - 0.043 12.7 0.0 0.075 11.9 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF2974 PF11187.8 KXT00719.1 - 0.098 12.2 0.0 0.22 11.1 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2974) Chlorophyllase PF07224.11 KXT00719.1 - 0.15 11.1 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase ABC_membrane PF00664.23 KXT00720.1 - 4.2e-86 289.0 21.2 3.7e-47 161.3 8.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXT00720.1 - 1.2e-56 191.0 0.0 7.8e-28 97.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KXT00720.1 - 4.3e-17 62.3 2.5 3.1e-05 23.5 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KXT00720.1 - 4.4e-11 43.2 0.3 0.00022 21.5 0.0 3.8 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KXT00720.1 - 1.2e-08 34.6 1.8 0.0042 16.8 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 KXT00720.1 - 2.8e-08 33.0 4.4 0.0017 17.2 0.0 3.8 4 0 0 4 4 4 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 KXT00720.1 - 3.3e-07 30.4 0.7 0.021 14.7 0.0 2.9 3 0 0 3 3 2 2 RsgA GTPase AAA_21 PF13304.6 KXT00720.1 - 1.1e-06 28.7 2.5 0.2 11.4 0.0 4.2 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KXT00720.1 - 1.3e-06 28.4 0.5 0.03 14.0 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_16 PF13191.6 KXT00720.1 - 4.7e-06 27.1 0.1 0.075 13.4 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 KXT00720.1 - 1.9e-05 25.3 1.1 0.083 13.4 0.3 2.8 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KXT00720.1 - 2e-05 24.4 0.0 0.047 13.4 0.0 3.2 3 1 0 3 3 3 1 AAA domain AAA_5 PF07728.14 KXT00720.1 - 0.0007 19.6 0.1 0.25 11.4 0.0 3.2 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 KXT00720.1 - 0.00072 19.9 0.1 0.023 15.0 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 KXT00720.1 - 0.0014 18.2 0.1 4.6 6.8 0.0 3.8 4 0 0 4 4 3 0 AAA domain AAA_33 PF13671.6 KXT00720.1 - 0.0029 17.8 0.1 1.6 8.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KXT00720.1 - 0.0042 17.6 0.2 4.7 7.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KXT00720.1 - 0.0045 16.7 0.4 2.6 7.7 0.1 2.9 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KXT00720.1 - 0.0053 16.8 0.1 2.8 8.1 0.1 3.3 3 0 0 3 3 3 1 50S ribosome-binding GTPase DUF87 PF01935.17 KXT00720.1 - 0.0072 16.5 1.9 0.57 10.2 0.1 3.3 3 0 0 3 3 3 1 Helicase HerA, central domain Sigma54_activ_2 PF14532.6 KXT00720.1 - 0.0081 16.3 0.0 5.7 7.0 0.0 3.2 3 0 0 3 3 3 0 Sigma-54 interaction domain DUF3987 PF13148.6 KXT00720.1 - 0.0088 15.1 0.1 1.1 8.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) PhoH PF02562.16 KXT00720.1 - 0.012 15.0 0.3 14 5.1 0.0 3.4 3 0 0 3 3 3 0 PhoH-like protein NACHT PF05729.12 KXT00720.1 - 0.014 15.4 0.2 2.9 7.8 0.1 3.1 2 1 0 2 2 2 0 NACHT domain FtsK_SpoIIIE PF01580.18 KXT00720.1 - 0.018 14.4 0.0 2.2 7.5 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family APS_kinase PF01583.20 KXT00720.1 - 0.021 14.7 0.2 4.7 7.1 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_13 PF13166.6 KXT00720.1 - 0.023 13.4 0.9 6.1 5.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 KXT00720.1 - 0.024 13.9 0.0 2.5 7.3 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.22 KXT00720.1 - 0.038 14.4 0.4 15 6.1 0.0 2.9 3 0 0 3 3 2 0 RNA helicase NB-ARC PF00931.22 KXT00720.1 - 0.062 12.5 0.1 11 5.1 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain G-alpha PF00503.20 KXT00720.1 - 0.064 12.4 0.0 6.7 5.8 0.0 2.6 2 0 0 2 2 2 0 G-protein alpha subunit CPT PF07931.12 KXT00720.1 - 0.064 13.1 0.2 8.2 6.2 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_7 PF12775.7 KXT00720.1 - 0.077 12.5 0.1 16 4.9 0.0 2.7 3 0 0 3 3 2 0 P-loop containing dynein motor region PRK PF00485.18 KXT00720.1 - 0.084 12.6 0.3 3.8 7.2 0.1 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family SbcCD_C PF13558.6 KXT00720.1 - 0.1 12.8 0.2 11 6.3 0.0 3.4 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Sigma54_activat PF00158.26 KXT00720.1 - 0.11 12.1 0.0 14 5.4 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_10 PF12846.7 KXT00720.1 - 0.14 11.1 0.0 15 4.3 0.1 2.6 2 0 0 2 2 2 0 AAA-like domain CoaE PF01121.20 KXT00720.1 - 0.23 11.1 1.3 2.7 7.6 0.4 2.6 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_28 PF13521.6 KXT00720.1 - 0.93 9.7 2.8 5 7.4 0.5 3.0 3 0 0 3 3 2 0 AAA domain ATPase PF06745.13 KXT00720.1 - 1.6 8.0 8.1 25 4.1 0.1 3.8 4 0 0 4 4 4 0 KaiC Lactamase_B PF00753.27 KXT00721.1 - 2.5e-17 63.5 5.8 3.3e-17 63.2 5.8 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXT00721.1 - 0.0074 15.8 0.6 0.011 15.2 0.6 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF2300 PF10062.9 KXT00721.1 - 0.16 12.0 0.3 0.28 11.3 0.3 1.3 1 0 0 1 1 1 0 Predicted secreted protein (DUF2300) Polysacc_synt_4 PF04669.13 KXT00724.1 - 2.3e-21 76.2 1.3 6.9e-20 71.4 1.3 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis MFS_1 PF07690.16 KXT00725.1 - 6.5e-27 94.4 17.9 6.5e-27 94.4 17.9 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KXT00725.1 - 0.013 13.9 3.2 0.036 12.5 3.2 1.6 1 1 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) DUF3040 PF11239.8 KXT00725.1 - 0.11 12.8 0.1 0.11 12.8 0.1 3.1 5 0 0 5 5 5 0 Protein of unknown function (DUF3040) Mito_carr PF00153.27 KXT00726.1 - 6.4e-60 199.1 1.6 6.5e-19 67.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KXT00726.1 - 0.015 14.5 0.2 0.11 11.6 0.1 2.5 3 0 0 3 3 3 0 Gammaproteobacterial serine protease His_Phos_1 PF00300.22 KXT00727.1 - 8.6e-33 113.7 2.9 2.1e-15 56.9 0.1 2.5 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) DUF3425 PF11905.8 KXT00728.1 - 5.2e-15 55.5 0.0 1.4e-14 54.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 KXT00728.1 - 0.036 14.2 4.5 0.089 12.9 4.5 1.7 1 0 0 1 1 1 0 bZIP transcription factor RP-C_C PF11800.8 KXT00728.1 - 0.25 11.4 5.5 0.6 10.2 5.5 1.5 1 1 0 1 1 1 0 Replication protein C C-terminal region OsmC PF02566.19 KXT00729.1 - 1.5e-15 57.5 0.0 2.3e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 OsmC-like protein Rep_fac-A_3 PF08661.11 KXT00729.1 - 0.024 15.0 0.0 0.044 14.1 0.0 1.4 1 0 0 1 1 1 0 Replication factor A protein 3 Ribosomal_L6e PF01159.19 KXT00730.1 - 1.8e-40 137.9 0.1 2.8e-40 137.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e GNAT_acetyltr_2 PF13718.6 KXT00730.1 - 0.022 14.1 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 ADH_N_2 PF16884.5 KXT00732.1 - 5.9e-28 96.9 0.0 9.3e-28 96.3 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KXT00732.1 - 9.2e-21 74.2 0.1 1.5e-20 73.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXT00732.1 - 0.0017 19.4 0.0 0.0048 18.0 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PhoH PF02562.16 KXT00732.1 - 0.0028 17.1 0.3 0.025 14.1 0.0 2.0 2 0 0 2 2 2 1 PhoH-like protein TrkA_N PF02254.18 KXT00732.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Fungal_trans PF04082.18 KXT00733.1 - 5.4e-17 61.7 0.0 9.1e-17 60.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT00733.1 - 5.3e-06 26.4 9.3 9.5e-06 25.6 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MDMPI_N PF11716.8 KXT00733.1 - 0.2 12.3 0.6 0.48 11.1 0.6 1.6 1 0 0 1 1 1 0 Mycothiol maleylpyruvate isomerase N-terminal domain DUF2457 PF10446.9 KXT00734.1 - 6e-126 421.3 36.3 6e-126 421.3 36.3 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF2457) 2OG-FeII_Oxy_3 PF13640.6 KXT00736.1 - 1.5e-12 48.2 0.1 2.3e-12 47.6 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF5337 PF17272.2 KXT00736.1 - 0.13 12.2 0.2 0.27 11.1 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5337) SET PF00856.28 KXT00737.1 - 1.3e-16 61.5 0.0 2.7e-16 60.4 0.0 1.5 1 1 0 1 1 1 1 SET domain MFS_1 PF07690.16 KXT00738.1 - 2e-41 142.1 39.3 2e-41 142.1 39.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXT00738.1 - 3.5e-11 42.6 11.1 3.5e-11 42.6 11.1 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter MS_channel PF00924.18 KXT00738.1 - 2.5 7.6 4.6 1 8.9 1.4 2.0 2 0 0 2 2 2 0 Mechanosensitive ion channel Nup188_C PF18378.1 KXT00739.1 - 1.7e-104 349.6 0.0 4.6e-104 348.2 0.0 1.8 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain Nup188 PF10487.9 KXT00739.1 - 5.3e-49 167.0 0.1 1.7e-30 105.7 0.0 4.0 4 0 0 4 4 4 3 Nucleoporin subcomplex protein binding to Pom34 PAN_1 PF00024.26 KXT00740.1 - 0.0047 16.9 0.2 0.0095 15.9 0.2 1.4 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 KXT00740.1 - 0.0064 16.4 0.5 0.015 15.2 0.5 1.6 1 0 0 1 1 1 1 PAN domain Abhydrolase_2 PF02230.16 KXT00740.1 - 0.016 15.1 0.0 2.6 7.8 0.0 2.4 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Esterase_phd PF10503.9 KXT00740.1 - 0.067 12.7 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Esterase PHB depolymerase AXE1 PF05448.12 KXT00740.1 - 0.13 10.9 0.0 0.22 10.2 0.0 1.4 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Aminotran_1_2 PF00155.21 KXT00749.1 - 4.2e-22 78.8 0.0 5.4e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KXT00749.1 - 6.9e-06 25.6 0.1 4e-05 23.1 0.1 1.9 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_MocR PF12897.7 KXT00749.1 - 0.0091 14.8 0.0 0.016 14.0 0.0 1.4 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase OKR_DC_1 PF01276.20 KXT00749.1 - 0.13 10.9 0.0 0.2 10.3 0.0 1.1 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Use1 PF09753.9 KXT00750.1 - 1.8 8.2 7.7 3.2 7.4 7.7 1.3 1 0 0 1 1 1 0 Membrane fusion protein Use1 HsbA PF12296.8 KXT00751.1 - 3.3e-22 79.2 2.0 4.6e-22 78.7 2.0 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A DUF885 PF05960.11 KXT00751.1 - 0.034 13.8 0.3 0.041 13.5 0.3 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) BPL_LplA_LipB_2 PF16917.5 KXT00751.1 - 0.11 12.0 0.8 0.77 9.3 0.1 2.5 2 1 1 3 3 3 0 Biotin/lipoate A/B protein ligase family CRAL_TRIO PF00650.20 KXT00752.1 - 7.2e-24 84.3 0.0 1.4e-23 83.3 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KXT00752.1 - 1.2e-10 41.4 0.1 3.2e-10 40.0 0.1 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Nop16 PF09420.10 KXT00752.1 - 0.45 10.5 3.4 1.7 8.6 3.2 2.0 2 0 0 2 2 2 0 Ribosome biogenesis protein Nop16 p450 PF00067.22 KXT00753.1 - 8.5e-55 186.3 0.0 1.1e-54 185.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 APAF1_C PF17908.1 KXT00753.1 - 0.003 17.5 1.2 2.9 7.9 0.0 2.7 2 1 1 3 3 3 2 APAF-1 helical domain Glyco_hydro_16 PF00722.21 KXT00754.1 - 4e-35 120.9 3.9 8.6e-35 119.8 3.9 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Podoplanin PF05808.11 KXT00754.1 - 0.025 14.7 0.0 0.048 13.8 0.0 1.4 1 0 0 1 1 1 0 Podoplanin TMEM132D_C PF15706.5 KXT00754.1 - 0.15 11.9 0.2 0.68 9.8 0.0 2.0 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Glyco_hydro_3 PF00933.21 KXT00755.1 - 8.8e-49 166.6 0.0 1.3e-48 166.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KXT00755.1 - 2.2e-40 138.8 0.0 3e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain PA14 PF07691.12 KXT00755.1 - 5.2e-10 39.3 0.0 1.8e-09 37.6 0.0 1.9 1 1 1 2 2 2 1 PA14 domain DUF5490 PF17593.2 KXT00755.1 - 0.053 13.5 0.0 15 5.7 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5490) MFS_1 PF07690.16 KXT00756.1 - 2.3e-10 40.0 32.8 2.3e-10 40.0 32.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KXT00756.1 - 4e-05 22.6 0.3 5.2e-05 22.3 0.3 1.5 1 1 0 1 1 1 1 MFS_1 like family LacY_symp PF01306.19 KXT00756.1 - 0.0008 18.3 0.4 0.0014 17.5 0.4 1.3 1 0 0 1 1 1 1 LacY proton/sugar symporter Cpn60_TCP1 PF00118.24 KXT00757.1 - 4.6e-155 517.0 4.4 5.2e-155 516.8 4.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PNTB_4TM PF12769.7 KXT00757.1 - 0.12 12.9 0.3 0.75 10.3 0.0 2.4 3 0 0 3 3 3 0 4TM region of pyridine nucleotide transhydrogenase, mitoch Ribosomal_S26e PF01283.19 KXT00758.1 - 5.9e-52 174.7 8.7 7e-52 174.4 8.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e zf_CopZ PF18423.1 KXT00758.1 - 0.042 13.8 1.5 0.059 13.3 0.0 2.0 3 0 0 3 3 3 0 Zinc binding domain DUF4668 PF15701.5 KXT00758.1 - 0.076 12.8 0.3 0.12 12.2 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4668) DUF1918 PF08940.11 KXT00758.1 - 0.095 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) SF1-HH PF16275.5 KXT00758.1 - 0.22 11.9 1.5 0.28 11.6 1.5 1.3 1 1 0 1 1 1 0 Splicing factor 1 helix-hairpin domain DUF3328 PF11807.8 KXT00759.1 - 8.7e-31 107.4 0.7 9.8e-31 107.2 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF2512 PF10710.9 KXT00759.1 - 0.63 9.7 2.8 0.52 10.0 0.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2512) TMV_coat PF00721.21 KXT00760.1 - 0.065 13.1 0.5 0.074 12.9 0.5 1.1 1 0 0 1 1 1 0 Virus coat protein (TMV like) FlxA PF14282.6 KXT00760.1 - 0.2 11.7 2.7 0.51 10.4 2.7 1.8 1 1 0 1 1 1 0 FlxA-like protein TFIIF_beta_N PF17683.1 KXT00762.1 - 0.0013 19.5 0.3 0.0018 19.0 0.3 1.3 1 0 0 1 1 1 1 TFIIF, beta subunit N-terminus PHM7_cyt PF14703.6 KXT00762.1 - 0.0085 16.3 0.1 0.0095 16.2 0.1 1.1 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter DUF3849 PF12960.7 KXT00763.1 - 0.0069 16.4 0.0 0.0083 16.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3849) PKD_3 PF16820.5 KXT00763.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 PKD-like domain F-box-like_2 PF13013.6 KXT00764.1 - 0.18 11.8 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 F-box-like domain CYLD_phos_site PF16607.5 KXT00766.1 - 0.088 12.7 1.1 0.22 11.4 1.1 1.6 1 0 0 1 1 1 0 Phosphorylation region of CYLD, unstructured nec1 PF10379.9 KXT00766.1 - 0.77 9.2 8.1 0.052 13.0 3.3 1.5 2 0 0 2 2 2 0 Virulence protein nec1 DUF2345 PF10106.9 KXT00767.1 - 0.0098 15.8 0.0 0.026 14.4 0.0 1.6 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2345) Spo7_2_N PF15407.6 KXT00767.1 - 0.014 15.0 0.0 3.7 7.2 0.0 2.1 2 0 0 2 2 2 0 Sporulation protein family 7 DraK_HK_N PF18092.1 KXT00767.1 - 0.02 15.3 0.2 5.7 7.4 0.1 2.2 1 1 1 2 2 2 0 DraK Histidine Kinase N-terminal domain PCP_red PF08369.10 KXT00767.1 - 0.64 10.3 2.7 6.9 7.0 0.2 2.4 2 1 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit DUF1772 PF08592.11 KXT00769.1 - 5.9e-12 46.1 3.0 5.9e-12 46.1 3.0 2.0 1 1 0 2 2 2 1 Domain of unknown function (DUF1772) Mito_carr PF00153.27 KXT00770.1 - 2.8e-57 190.7 3.7 1.9e-21 75.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Rrn6 PF10214.9 KXT00772.1 - 0.14 10.6 7.5 1.6 7.1 1.5 2.2 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor DUF4692 PF15763.5 KXT00772.1 - 1.3 9.5 4.1 6.9 7.1 1.0 2.7 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) BCS1_N PF08740.11 KXT00772.1 - 1.4 8.9 0.0 1.4 8.9 0.0 2.9 4 0 0 4 4 4 0 BCS1 N terminal Nrap_D5 PF17406.2 KXT00773.1 - 7.8e-60 201.3 0.9 2.9e-59 199.5 0.5 2.0 2 0 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D4 PF17405.2 KXT00773.1 - 9.4e-60 201.6 0.0 1.6e-59 200.9 0.0 1.3 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap PF03813.14 KXT00773.1 - 2.8e-50 170.3 0.0 4.8e-50 169.6 0.0 1.4 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D3 PF17404.2 KXT00773.1 - 8.1e-43 146.3 0.0 1.8e-42 145.1 0.0 1.6 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D2 PF17403.2 KXT00773.1 - 5.6e-40 136.6 0.1 2.9e-39 134.3 0.0 2.1 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain Nrap_D6 PF17407.2 KXT00773.1 - 6.2e-37 126.8 0.0 1.5e-36 125.6 0.0 1.7 1 0 0 1 1 1 1 Nrap protein domain 6 Sporozoite_P67 PF05642.11 KXT00773.1 - 1.8 6.5 9.7 2.8 5.9 9.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.12 KXT00773.1 - 2.8 6.0 8.7 4 5.5 8.7 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 KXT00773.1 - 3.7 6.9 9.0 5.6 6.3 9.0 1.2 1 0 0 1 1 1 0 SDA1 AAA PF00004.29 KXT00774.1 - 3.2e-42 144.1 0.0 5.8e-42 143.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KXT00774.1 - 6.6e-31 106.1 0.1 2.5e-30 104.2 0.1 2.1 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 KXT00774.1 - 1.4e-22 79.5 8.4 3.3e-22 78.3 8.4 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain RuvB_N PF05496.12 KXT00774.1 - 3.2e-06 27.0 0.0 5.9e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KXT00774.1 - 3.5e-06 27.5 0.2 0.0016 18.9 0.0 3.1 2 1 1 3 3 3 1 AAA ATPase domain AAA_lid_3 PF17862.1 KXT00774.1 - 1.6e-05 24.6 0.0 0.00012 21.8 0.0 2.4 2 0 0 2 2 2 1 AAA+ lid domain AAA_2 PF07724.14 KXT00774.1 - 1.7e-05 25.0 0.1 0.0055 16.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KXT00774.1 - 5.1e-05 23.3 0.0 0.00023 21.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 KXT00774.1 - 5.2e-05 23.1 0.0 0.00011 22.0 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 KXT00774.1 - 7.2e-05 23.1 0.1 0.0045 17.3 0.1 2.6 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KXT00774.1 - 7.4e-05 23.1 0.0 0.012 16.0 0.0 2.6 2 0 0 2 2 2 1 RNA helicase TIP49 PF06068.13 KXT00774.1 - 8.1e-05 22.0 0.0 0.00014 21.2 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_14 PF13173.6 KXT00774.1 - 0.00016 21.7 0.0 0.00034 20.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 KXT00774.1 - 0.00022 20.5 0.0 0.0018 17.5 0.0 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 KXT00774.1 - 0.00066 20.2 0.1 0.002 18.7 0.0 2.1 2 1 0 2 2 1 1 AAA domain AAA_24 PF13479.6 KXT00774.1 - 0.00082 19.1 0.1 0.0051 16.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KXT00774.1 - 0.0014 18.8 0.0 0.0044 17.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KXT00774.1 - 0.0091 15.3 0.3 1.5 8.0 0.1 3.1 2 1 1 3 3 3 1 Zeta toxin AAA_17 PF13207.6 KXT00774.1 - 0.012 16.0 0.1 0.057 13.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KXT00774.1 - 0.014 15.0 0.1 0.64 9.6 0.1 2.4 1 1 1 2 2 2 0 AAA domain USP8_dimer PF08969.11 KXT00774.1 - 0.016 15.3 4.3 0.035 14.3 4.3 1.5 1 0 0 1 1 1 0 USP8 dimerisation domain AAA_7 PF12775.7 KXT00774.1 - 0.022 14.3 0.0 0.13 11.8 0.0 2.2 2 1 0 2 2 2 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 KXT00774.1 - 0.025 13.9 0.0 0.082 12.3 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Torsin PF06309.11 KXT00774.1 - 0.032 14.3 0.0 0.087 12.9 0.0 1.7 2 0 0 2 2 1 0 Torsin Parvo_NS1 PF01057.17 KXT00774.1 - 0.043 12.9 0.0 0.1 11.6 0.0 1.5 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Cytidylate_kin PF02224.18 KXT00774.1 - 0.068 12.9 0.7 0.51 10.0 0.0 2.4 2 1 0 2 2 2 0 Cytidylate kinase PhoH PF02562.16 KXT00774.1 - 0.073 12.5 0.1 0.16 11.4 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.12 KXT00774.1 - 0.074 13.0 0.0 0.69 9.8 0.0 2.1 1 1 1 2 2 2 0 NACHT domain CPT PF07931.12 KXT00774.1 - 0.11 12.4 0.0 0.57 10.0 0.0 2.0 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein KAP_NTPase PF07693.14 KXT00774.1 - 0.23 10.7 1.4 44 3.2 0.0 2.9 2 1 1 3 3 3 0 KAP family P-loop domain TPR_1 PF00515.28 KXT00774.1 - 0.28 11.1 6.3 0.44 10.4 4.1 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat ATPase_2 PF01637.18 KXT00774.1 - 0.33 10.8 2.2 1.3 8.9 0.0 2.6 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea AAA PF00004.29 KXT00775.1 - 3.2e-42 144.1 0.0 5.8e-42 143.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KXT00775.1 - 6.6e-31 106.1 0.1 2.5e-30 104.2 0.1 2.1 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 KXT00775.1 - 1.4e-22 79.5 8.4 3.3e-22 78.3 8.4 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain RuvB_N PF05496.12 KXT00775.1 - 3.2e-06 27.0 0.0 5.9e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KXT00775.1 - 3.5e-06 27.5 0.2 0.0016 18.9 0.0 3.1 2 1 1 3 3 3 1 AAA ATPase domain AAA_lid_3 PF17862.1 KXT00775.1 - 1.6e-05 24.6 0.0 0.00012 21.8 0.0 2.4 2 0 0 2 2 2 1 AAA+ lid domain AAA_2 PF07724.14 KXT00775.1 - 1.7e-05 25.0 0.1 0.0055 16.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KXT00775.1 - 5.1e-05 23.3 0.0 0.00023 21.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 KXT00775.1 - 5.2e-05 23.1 0.0 0.00011 22.0 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 KXT00775.1 - 7.2e-05 23.1 0.1 0.0045 17.3 0.1 2.6 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KXT00775.1 - 7.4e-05 23.1 0.0 0.012 16.0 0.0 2.6 2 0 0 2 2 2 1 RNA helicase TIP49 PF06068.13 KXT00775.1 - 8.1e-05 22.0 0.0 0.00014 21.2 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_14 PF13173.6 KXT00775.1 - 0.00016 21.7 0.0 0.00034 20.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 KXT00775.1 - 0.00022 20.5 0.0 0.0018 17.5 0.0 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 KXT00775.1 - 0.00066 20.2 0.1 0.002 18.7 0.0 2.1 2 1 0 2 2 1 1 AAA domain AAA_24 PF13479.6 KXT00775.1 - 0.00082 19.1 0.1 0.0051 16.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KXT00775.1 - 0.0014 18.8 0.0 0.0044 17.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KXT00775.1 - 0.0091 15.3 0.3 1.5 8.0 0.1 3.1 2 1 1 3 3 3 1 Zeta toxin AAA_17 PF13207.6 KXT00775.1 - 0.012 16.0 0.1 0.057 13.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KXT00775.1 - 0.014 15.0 0.1 0.64 9.6 0.1 2.4 1 1 1 2 2 2 0 AAA domain USP8_dimer PF08969.11 KXT00775.1 - 0.016 15.3 4.3 0.035 14.3 4.3 1.5 1 0 0 1 1 1 0 USP8 dimerisation domain AAA_7 PF12775.7 KXT00775.1 - 0.022 14.3 0.0 0.13 11.8 0.0 2.2 2 1 0 2 2 2 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 KXT00775.1 - 0.025 13.9 0.0 0.082 12.3 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Torsin PF06309.11 KXT00775.1 - 0.032 14.3 0.0 0.087 12.9 0.0 1.7 2 0 0 2 2 1 0 Torsin Parvo_NS1 PF01057.17 KXT00775.1 - 0.043 12.9 0.0 0.1 11.6 0.0 1.5 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Cytidylate_kin PF02224.18 KXT00775.1 - 0.068 12.9 0.7 0.51 10.0 0.0 2.4 2 1 0 2 2 2 0 Cytidylate kinase PhoH PF02562.16 KXT00775.1 - 0.073 12.5 0.1 0.16 11.4 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.12 KXT00775.1 - 0.074 13.0 0.0 0.69 9.8 0.0 2.1 1 1 1 2 2 2 0 NACHT domain CPT PF07931.12 KXT00775.1 - 0.11 12.4 0.0 0.57 10.0 0.0 2.0 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein KAP_NTPase PF07693.14 KXT00775.1 - 0.23 10.7 1.4 44 3.2 0.0 2.9 2 1 1 3 3 3 0 KAP family P-loop domain TPR_1 PF00515.28 KXT00775.1 - 0.28 11.1 6.3 0.44 10.4 4.1 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat ATPase_2 PF01637.18 KXT00775.1 - 0.33 10.8 2.2 1.3 8.9 0.0 2.6 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea bZIP_1 PF00170.21 KXT00776.1 - 0.017 15.2 7.2 0.037 14.1 7.1 1.6 1 1 0 1 1 1 0 bZIP transcription factor TMPIT PF07851.13 KXT00776.1 - 0.41 9.8 3.5 0.53 9.5 3.5 1.1 1 0 0 1 1 1 0 TMPIT-like protein Glyco_hydro_76 PF03663.14 KXT00779.1 - 1.2e-151 505.5 28.5 1.3e-151 505.3 28.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 MFS_1 PF07690.16 KXT00780.1 - 0.0072 15.3 15.8 0.019 13.9 14.9 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 KXT00780.1 - 0.051 11.9 3.8 0.14 10.5 3.8 1.6 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family MAPEG PF01124.18 KXT00781.1 - 0.035 14.0 0.0 0.07 13.0 0.0 1.5 1 0 0 1 1 1 0 MAPEG family MAPEG PF01124.18 KXT00782.1 - 0.035 14.0 0.0 0.07 13.0 0.0 1.5 1 0 0 1 1 1 0 MAPEG family AAA_24 PF13479.6 KXT00784.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Bromodomain PF00439.25 KXT00785.1 - 1.7e-35 120.9 6.0 1.7e-17 63.3 1.1 2.5 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 KXT00785.1 - 3.4e-16 59.2 0.2 7.6e-16 58.1 0.2 1.6 1 0 0 1 1 1 1 BAH domain TRI12 PF06609.13 KXT00786.1 - 7.1e-39 133.7 14.8 9.8e-39 133.2 14.8 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KXT00786.1 - 2e-17 63.1 41.7 2.7e-17 62.8 39.0 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily PC_rep PF01851.22 KXT00786.1 - 0.18 12.3 0.3 0.18 12.3 0.3 2.4 3 0 0 3 3 3 0 Proteasome/cyclosome repeat His_Phos_1 PF00300.22 KXT00787.1 - 2.1e-34 118.9 0.5 4.3e-27 95.1 1.1 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) OTU PF02338.19 KXT00788.1 - 1.9e-06 28.4 0.0 3e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease PB1 PF00564.24 KXT00788.1 - 0.041 13.8 0.0 0.54 10.2 0.0 2.4 2 0 0 2 2 2 0 PB1 domain DUF2318 PF10080.9 KXT00788.1 - 0.051 13.7 0.1 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) Prenylcys_lyase PF07156.14 KXT00789.1 - 1.8e-88 297.1 0.0 2.5e-88 296.6 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase Amino_oxidase PF01593.24 KXT00789.1 - 3.8e-14 52.8 0.0 5.6e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXT00789.1 - 5.5e-12 45.7 0.1 1.1e-11 44.8 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXT00789.1 - 1e-07 31.9 0.2 4.1e-05 23.3 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXT00789.1 - 3.7e-05 23.1 0.2 0.085 12.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXT00789.1 - 5.8e-05 23.1 0.1 0.0033 17.4 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KXT00789.1 - 0.0024 18.4 0.2 0.84 10.2 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KXT00789.1 - 0.013 15.2 0.1 0.57 9.8 0.1 2.5 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 KXT00789.1 - 0.021 14.1 0.0 0.036 13.3 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain K_oxygenase PF13434.6 KXT00789.1 - 0.024 13.8 0.1 0.38 9.8 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KXT00789.1 - 0.049 12.9 0.2 0.18 11.0 0.0 1.8 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.22 KXT00789.1 - 0.054 12.6 0.1 0.1 11.7 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KXT00789.1 - 0.063 12.4 0.2 0.32 10.0 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain Pheromone PF08015.11 KXT00789.1 - 0.1 13.6 0.1 0.32 12.1 0.1 1.8 1 0 0 1 1 1 0 Fungal mating-type pheromone PIR PF00399.19 KXT00790.1 - 2.1e-08 33.5 24.0 0.00039 19.9 5.7 2.7 2 0 0 2 2 2 2 Yeast PIR protein repeat TPR_12 PF13424.6 KXT00791.1 - 9.5e-11 41.8 0.9 1.3e-07 31.8 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 KXT00791.1 - 1.3e-07 31.2 0.6 0.00049 19.9 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXT00791.1 - 0.00017 22.1 2.3 0.33 11.6 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXT00791.1 - 0.00019 21.4 0.5 1.3 9.4 0.0 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat Pro_isomerase PF00160.21 KXT00791.1 - 0.00044 20.5 0.0 0.023 15.0 0.0 2.5 1 1 1 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF1045 PF06299.12 KXT00791.1 - 0.0062 16.5 1.0 0.023 14.7 1.0 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1045) TPR_2 PF07719.17 KXT00791.1 - 0.0079 16.2 7.6 1.1 9.5 0.1 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXT00791.1 - 0.0081 15.9 0.2 3.4 7.6 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXT00791.1 - 0.019 15.5 0.3 3.1 8.4 0.0 3.8 3 1 1 4 4 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KXT00791.1 - 0.034 14.2 2.1 0.1 12.7 0.1 2.9 3 0 0 3 3 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 KXT00791.1 - 0.037 14.8 2.5 11 7.1 0.1 3.9 2 1 1 3 3 3 0 Tetratricopeptide repeat FliS PF02561.14 KXT00791.1 - 0.11 12.7 0.6 0.58 10.4 0.0 2.5 2 0 0 2 2 2 0 Flagellar protein FliS COG2 PF06148.11 KXT00791.1 - 9.7 6.3 7.2 69 3.5 0.0 3.5 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 ATP-grasp_3 PF02655.14 KXT00793.1 - 0.13 12.3 0.0 0.33 11.0 0.0 1.8 1 1 0 1 1 1 0 ATP-grasp domain AAA PF00004.29 KXT00794.1 - 8e-19 68.4 0.0 2e-18 67.1 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXT00794.1 - 0.00019 21.8 0.3 0.00069 20.0 0.3 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 KXT00794.1 - 0.00032 20.3 0.0 0.00057 19.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KXT00794.1 - 0.0014 18.6 0.0 0.0032 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXT00794.1 - 0.013 15.7 0.2 0.042 14.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KXT00794.1 - 0.04 14.2 0.0 0.088 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KXT00794.1 - 0.054 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_24 PF13479.6 KXT00794.1 - 0.15 11.7 0.1 0.37 10.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 KXT00794.1 - 0.19 11.5 0.0 0.34 10.7 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain DUF3659 PF12396.8 KXT00796.1 - 4.2e-15 55.4 1.1 5.7e-15 55.0 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3659) UPF0203 PF05254.12 KXT00797.1 - 2.3e-28 98.2 3.4 2.7e-28 98.0 3.4 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.13 KXT00797.1 - 6.4e-05 23.2 0.6 0.00018 21.8 0.6 1.6 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 KXT00797.1 - 0.0019 18.2 4.2 0.1 12.6 0.2 2.4 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like UCR_hinge PF02320.16 KXT00797.1 - 0.069 13.4 5.1 1.5 9.0 0.6 2.2 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein DUF5339 PF17274.2 KXT00797.1 - 0.14 13.0 2.8 0.64 10.9 0.7 2.3 2 1 0 2 2 2 0 Family of unknown function (DUF5339) Cys_Met_Meta_PP PF01053.20 KXT00798.1 - 9.5e-33 113.2 0.0 1.3e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KXT00798.1 - 0.06 12.5 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II AAA_12 PF13087.6 KXT00799.1 - 3e-13 49.8 0.0 6.4e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXT00799.1 - 3.2e-06 27.0 0.2 2.5e-05 24.1 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KXT00799.1 - 0.00024 21.0 2.2 0.00068 19.5 2.2 1.7 1 1 0 1 1 1 1 AAA domain NT5C PF06941.12 KXT00799.1 - 0.019 14.8 0.0 0.045 13.6 0.0 1.5 1 0 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) ResIII PF04851.15 KXT00799.1 - 0.09 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Pyocin_S PF06958.12 KXT00799.1 - 0.19 12.3 0.0 0.19 12.3 0.0 3.0 3 0 0 3 3 3 0 S-type Pyocin CbiA PF01656.23 KXT00799.1 - 0.83 9.7 2.7 1.9 8.5 2.7 1.8 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain CorA PF01544.18 KXT00800.1 - 6.1e-06 25.8 2.0 2.7e-05 23.6 2.3 1.8 1 1 1 2 2 2 1 CorA-like Mg2+ transporter protein Saf_2TM PF18303.1 KXT00800.1 - 0.012 15.2 0.6 0.021 14.4 0.6 1.4 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain CobN-Mg_chel PF02514.16 KXT00800.1 - 0.094 10.4 0.1 0.12 10.1 0.1 1.1 1 0 0 1 1 1 0 CobN/Magnesium Chelatase FAM209 PF15206.6 KXT00800.1 - 0.12 12.1 0.6 1.4 8.7 0.5 2.5 3 0 0 3 3 3 0 FAM209 family Acetyltransf_10 PF13673.7 KXT00801.1 - 8.2e-11 41.9 0.0 1.5e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXT00801.1 - 5.3e-08 33.1 0.0 1.1e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXT00801.1 - 1.4e-07 31.8 0.0 3.1e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Zn_clus PF00172.18 KXT00801.1 - 7.2e-06 26.0 10.2 1.7e-05 24.8 10.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 KXT00802.1 - 2.2e-72 244.3 0.0 2.5e-72 244.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M48_N PF16491.5 KXT00802.1 - 0.83 9.5 4.1 1.6 8.6 4.1 1.4 1 0 0 1 1 1 0 CAAX prenyl protease N-terminal, five membrane helices ADH_N PF08240.12 KXT00803.1 - 2e-05 24.4 0.0 4e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXT00803.1 - 0.021 14.8 0.0 0.038 14.0 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Glyco_hydro_43 PF04616.14 KXT00806.1 - 8.7e-30 104.0 0.0 1.4e-29 103.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Fig1 PF12351.8 KXT00807.1 - 7.6e-56 189.0 3.4 1.6e-55 187.9 3.4 1.6 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.12 KXT00807.1 - 3.1e-06 27.0 4.8 5.2e-06 26.2 4.8 1.3 1 0 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.13 KXT00807.1 - 0.0045 16.1 2.4 0.0078 15.3 2.4 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF898) HsbA PF12296.8 KXT00808.1 - 9.2e-18 64.8 13.2 9.2e-18 64.8 13.2 1.6 2 0 0 2 2 2 1 Hydrophobic surface binding protein A NPV_P10 PF05531.12 KXT00808.1 - 0.026 15.0 1.1 0.095 13.2 0.1 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein CUT PF02376.15 KXT00808.1 - 0.043 14.0 0.0 0.098 12.8 0.0 1.6 1 0 0 1 1 1 0 CUT domain Rsd_AlgQ PF04353.13 KXT00808.1 - 0.055 13.4 0.1 0.35 10.8 0.1 1.9 2 0 0 2 2 2 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Endotoxin_N PF03945.14 KXT00808.1 - 0.2 11.3 0.0 0.36 10.5 0.0 1.3 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain Phage_GP20 PF06810.11 KXT00808.1 - 0.36 10.6 5.0 4.2 7.2 5.0 2.0 1 1 0 1 1 1 0 Phage minor structural protein GP20 MT0933_antitox PF14013.6 KXT00809.1 - 0.0033 17.7 1.5 1.1 9.7 0.1 2.1 1 1 1 2 2 2 2 MT0933-like antitoxin protein HLH PF00010.26 KXT00809.1 - 0.013 15.5 0.1 0.18 11.8 0.0 2.1 2 0 0 2 2 2 0 Helix-loop-helix DNA-binding domain DHQ_synthase PF01761.20 KXT00812.1 - 1.7e-52 178.2 0.0 2.7e-52 177.5 0.0 1.2 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 KXT00812.1 - 4.2e-11 43.0 0.0 6.7e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DNA_ligase_A_M PF01068.21 KXT00813.1 - 3.4e-50 170.5 0.2 2.3e-47 161.3 0.0 2.4 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KXT00813.1 - 4e-37 128.2 0.0 8.8e-37 127.1 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KXT00813.1 - 1.6e-17 63.9 0.0 4.9e-17 62.4 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region mRNA_cap_enzyme PF01331.19 KXT00813.1 - 0.044 13.6 0.1 11 5.8 0.0 2.4 2 0 0 2 2 2 0 mRNA capping enzyme, catalytic domain Rtt106_N PF18215.1 KXT00815.1 - 0.041 13.6 0.0 0.095 12.5 0.0 1.6 1 0 0 1 1 1 0 Histone chaperone Rtt106 N-terminal domain F-box-like_2 PF13013.6 KXT00815.1 - 0.13 12.3 0.0 0.35 10.9 0.0 1.8 2 0 0 2 2 2 0 F-box-like domain CBS PF00571.28 KXT00816.1 - 1.2e-35 121.7 4.8 8.8e-10 38.9 0.0 6.1 6 0 0 6 6 6 4 CBS domain PB1 PF00564.24 KXT00816.1 - 1.3e-09 37.8 0.0 5.3e-09 35.9 0.0 2.1 2 1 0 2 2 2 1 PB1 domain Coilin_N PF15862.5 KXT00816.1 - 0.88 9.4 4.8 2.4 8.0 1.0 2.3 2 0 0 2 2 2 0 Coilin N-terminus DnaJ PF00226.31 KXT00817.1 - 5.6e-25 87.3 0.6 5.6e-25 87.3 0.6 2.4 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.8 KXT00817.1 - 1e-11 44.8 3.6 1e-11 44.8 3.6 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXT00817.1 - 7.7e-10 38.8 9.3 1.1e-08 35.2 2.0 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KXT00817.1 - 3.2e-06 27.4 3.8 0.0029 17.9 2.2 2.9 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KXT00817.1 - 1e-05 25.9 3.7 0.063 14.1 0.6 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KXT00817.1 - 0.002 18.1 6.6 0.1 12.7 0.6 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KXT00817.1 - 0.0024 18.2 6.7 0.1 13.1 1.3 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type AKAP95 PF04988.12 KXT00817.1 - 0.15 12.3 5.2 0.28 11.4 2.0 2.5 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) DUF3328 PF11807.8 KXT00818.1 - 2.9e-30 105.7 0.1 4e-30 105.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) PhzC-PhzF PF02567.16 KXT00819.1 - 0.0077 15.7 0.3 1.3 8.4 0.0 2.9 1 1 2 3 3 3 3 Phenazine biosynthesis-like protein Prefoldin_2 PF01920.20 KXT00820.1 - 2.7e-23 81.9 14.7 3.5e-23 81.6 14.7 1.2 1 0 0 1 1 1 1 Prefoldin subunit MIP-T3_C PF17749.1 KXT00820.1 - 0.0011 19.0 4.0 0.0011 19.0 4.0 2.1 2 1 0 2 2 2 1 Microtubule-binding protein MIP-T3 C-terminal region Prefoldin_3 PF13758.6 KXT00820.1 - 0.0013 18.7 5.3 0.0015 18.6 4.7 1.4 1 1 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 KXT00820.1 - 0.004 17.1 14.2 0.17 11.8 14.2 2.2 1 1 0 1 1 1 1 Prefoldin subunit Spc24 PF08286.11 KXT00820.1 - 0.0068 16.6 12.3 0.075 13.3 3.1 2.1 1 1 0 2 2 2 2 Spc24 subunit of Ndc80 Uso1_p115_C PF04871.13 KXT00820.1 - 0.013 15.8 12.0 0.017 15.5 3.5 2.2 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region CENP-F_leu_zip PF10473.9 KXT00820.1 - 0.014 15.5 12.2 0.35 10.9 2.5 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rx_N PF18052.1 KXT00820.1 - 0.014 15.6 7.0 0.96 9.8 0.2 2.2 2 0 0 2 2 2 0 Rx N-terminal domain FTA4 PF13093.6 KXT00820.1 - 0.045 13.6 4.9 0.054 13.4 4.9 1.3 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Fib_alpha PF08702.10 KXT00820.1 - 0.067 13.4 10.5 0.11 12.7 10.5 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.11 KXT00820.1 - 0.067 13.6 8.1 0.92 9.9 1.5 2.8 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.12 KXT00820.1 - 0.088 13.3 10.9 0.71 10.4 2.5 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF5446 PF17522.2 KXT00820.1 - 0.095 12.9 2.6 0.11 12.7 0.2 2.2 2 2 0 2 2 2 0 Family of unknown function (DUF5446) ERp29 PF07749.12 KXT00820.1 - 0.12 13.3 5.0 0.24 12.3 5.0 1.6 1 1 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain DASH_Dam1 PF08653.10 KXT00820.1 - 0.13 12.0 2.4 0.4 10.5 0.2 2.4 3 0 0 3 3 2 0 DASH complex subunit Dam1 DUF4200 PF13863.6 KXT00820.1 - 0.17 12.3 11.0 1 9.8 1.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) APG6_N PF17675.1 KXT00820.1 - 0.2 12.2 14.9 0.91 10.1 3.3 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region Spc7 PF08317.11 KXT00820.1 - 0.22 10.3 13.8 0.36 9.7 13.8 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF2312 PF10073.9 KXT00820.1 - 0.27 10.9 5.7 0.22 11.2 1.0 2.5 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) Sas10_Utp3 PF04000.15 KXT00820.1 - 0.32 11.7 6.2 5.4 7.7 0.9 2.3 2 0 0 2 2 2 0 Sas10/Utp3/C1D family PHM7_cyt PF14703.6 KXT00820.1 - 0.35 11.1 6.2 0.62 10.3 6.2 1.4 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Occludin_ELL PF07303.13 KXT00820.1 - 0.57 10.9 7.3 0.55 11.0 0.9 2.1 2 0 0 2 2 2 0 Occludin homology domain FliD_N PF02465.18 KXT00820.1 - 0.65 10.7 12.5 1.2e+02 3.5 12.5 2.9 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Osmo_CC PF08946.10 KXT00820.1 - 0.74 10.1 9.3 0.17 12.2 3.3 2.4 2 1 0 2 2 2 0 Osmosensory transporter coiled coil DUF5082 PF16888.5 KXT00820.1 - 0.8 10.0 13.7 8.5 6.7 13.7 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) ATG16 PF08614.11 KXT00820.1 - 0.81 9.9 13.0 0.67 10.1 3.1 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Tektin PF03148.14 KXT00820.1 - 1.1 7.9 13.0 0.31 9.8 3.6 2.0 2 0 0 2 2 2 0 Tektin family Fzo_mitofusin PF04799.13 KXT00820.1 - 1.2 8.7 8.8 1.4 8.4 0.9 2.2 2 0 0 2 2 2 0 fzo-like conserved region TPR_MLP1_2 PF07926.12 KXT00820.1 - 1.2 9.2 16.4 1.7 8.7 6.0 2.6 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein ABC_tran_CTD PF16326.5 KXT00820.1 - 1.6 9.0 16.3 2.9 8.2 1.1 3.3 2 2 1 3 3 3 0 ABC transporter C-terminal domain TMPIT PF07851.13 KXT00820.1 - 1.9 7.7 9.4 1.8 7.7 6.4 1.7 1 1 0 1 1 1 0 TMPIT-like protein DivIC PF04977.15 KXT00820.1 - 2 8.2 18.0 0.13 12.1 4.6 3.3 1 1 2 3 3 3 0 Septum formation initiator HAUS-augmin3 PF14932.6 KXT00820.1 - 2 7.9 13.2 0.45 10.1 6.9 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 XhlA PF10779.9 KXT00820.1 - 2.1 8.6 10.1 0.61 10.3 1.8 2.4 2 1 0 2 2 2 0 Haemolysin XhlA M PF02370.16 KXT00820.1 - 2.3 9.1 12.3 2.8 8.8 0.6 3.7 3 1 1 4 4 3 0 M protein repeat YabA PF06156.13 KXT00820.1 - 2.6 8.7 8.6 1.8 9.3 1.7 2.1 1 1 1 2 2 2 0 Initiation control protein YabA Fmp27_WPPW PF10359.9 KXT00820.1 - 2.6 6.8 11.6 1.2 7.9 2.5 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Macoilin PF09726.9 KXT00820.1 - 2.7 6.5 11.1 3.4 6.1 11.1 1.2 1 0 0 1 1 1 0 Macoilin family BRE1 PF08647.11 KXT00820.1 - 2.7 8.1 14.3 8.7 6.5 2.5 2.6 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF4407 PF14362.6 KXT00820.1 - 3.9 6.8 11.0 6.8 5.9 11.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4140 PF13600.6 KXT00820.1 - 7.1 7.1 10.9 16 6.0 3.5 2.6 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) UPF0242 PF06785.11 KXT00820.1 - 7.5 6.6 15.1 14 5.8 15.1 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Val_tRNA-synt_C PF10458.9 KXT00820.1 - 8.3 6.8 10.0 3.2 8.1 0.2 3.1 3 1 1 4 4 4 0 Valyl tRNA synthetase tRNA binding arm SPT_ssu-like PF11779.8 KXT00821.1 - 1.9e-12 46.6 1.5 2.5e-12 46.2 1.5 1.2 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like PRKCSH-like PF12999.7 KXT00822.1 - 0.053 13.3 0.4 0.072 12.9 0.4 1.2 1 0 0 1 1 1 0 Glucosidase II beta subunit-like ZapD PF07072.11 KXT00823.1 - 0.0011 18.7 0.0 0.0054 16.5 0.0 2.1 2 0 0 2 2 2 1 Cell division protein Sel1 PF08238.12 KXT00824.1 - 6.3e-17 61.6 29.8 2e-06 28.3 0.2 7.5 7 1 0 7 7 7 5 Sel1 repeat TPR_1 PF00515.28 KXT00824.1 - 0.0001 21.9 4.9 0.0021 17.8 0.2 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KXT00824.1 - 0.023 14.8 6.6 0.59 10.4 0.2 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4244 PF14029.6 KXT00824.1 - 0.16 11.4 0.3 18 4.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4244) COesterase PF00135.28 KXT00825.1 - 6.8e-80 269.4 0.0 7.9e-80 269.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXT00825.1 - 5.5e-08 32.9 0.5 1.8e-07 31.3 0.1 2.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold DUF4265 PF14085.6 KXT00825.1 - 0.096 12.7 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4265) DUF2358 PF10184.9 KXT00826.1 - 0.059 13.6 0.1 0.3 11.4 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2358) SnoaL_2 PF12680.7 KXT00826.1 - 0.13 13.0 0.0 0.24 12.0 0.0 1.5 1 0 0 1 1 1 0 SnoaL-like domain GTP_EFTU PF00009.27 KXT00827.1 - 5.9e-33 114.0 4.1 1.5e-31 109.5 4.1 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KXT00827.1 - 5.1e-26 90.8 0.0 1.1e-25 89.8 0.0 1.5 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 KXT00827.1 - 9.3e-09 35.4 0.1 2e-08 34.3 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase zf-CCHC PF00098.23 KXT00827.1 - 5.2e-08 32.6 9.2 0.00021 21.2 1.4 2.4 2 0 0 2 2 2 2 Zinc knuckle IF2_N PF04760.15 KXT00827.1 - 3.1e-07 30.1 0.0 8.6e-07 28.7 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region RsgA_GTPase PF03193.16 KXT00827.1 - 1.1e-05 25.4 0.8 7.5e-05 22.7 0.2 2.3 1 1 1 2 2 2 1 RsgA GTPase GTP_EFTU_D2 PF03144.25 KXT00827.1 - 2.4e-05 24.6 4.1 0.0065 16.8 0.7 2.9 2 0 0 2 2 2 2 Elongation factor Tu domain 2 Arf PF00025.21 KXT00827.1 - 6e-05 22.6 0.0 0.00011 21.7 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.18 KXT00827.1 - 0.00016 21.2 0.2 0.00032 20.2 0.2 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B MeaB PF03308.16 KXT00827.1 - 0.00024 20.2 2.3 0.0005 19.1 2.3 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB zf-CCHC_5 PF14787.6 KXT00827.1 - 0.0011 18.6 4.6 0.0011 18.6 4.6 2.5 1 1 1 2 2 2 1 GAG-polyprotein viral zinc-finger GTP_EFTU_D4 PF14578.6 KXT00827.1 - 0.0021 18.0 2.3 0.07 13.0 1.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 4 zf-CCHC_4 PF14392.6 KXT00827.1 - 0.0027 17.4 2.8 0.088 12.6 0.2 2.6 2 0 0 2 2 2 1 Zinc knuckle Ras PF00071.22 KXT00827.1 - 0.0086 15.7 0.1 0.023 14.3 0.1 1.7 1 0 0 1 1 1 1 Ras family GcrA PF07750.11 KXT00827.1 - 0.0088 16.5 0.3 0.0088 16.5 0.3 4.8 5 1 1 6 6 5 1 GcrA cell cycle regulator PduV-EutP PF10662.9 KXT00827.1 - 0.026 14.3 0.3 0.068 12.9 0.3 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 KXT00827.1 - 0.031 13.7 0.0 0.069 12.6 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Roc PF08477.13 KXT00827.1 - 0.048 13.9 0.1 0.2 11.9 0.0 2.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase HTH_24 PF13412.6 KXT00827.1 - 0.074 12.6 0.1 0.61 9.7 0.0 2.5 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding DUF3854 PF12965.7 KXT00827.1 - 0.095 12.7 0.1 0.27 11.2 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) MMR_HSR1_Xtn PF16897.5 KXT00827.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain zf-CCHC_3 PF13917.6 KXT00827.1 - 0.19 11.7 5.3 0.7 9.9 0.4 2.7 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.6 KXT00827.1 - 0.42 10.5 10.5 1.5 8.7 2.5 3.1 2 1 1 3 3 3 0 Zinc knuckle TPP_enzyme_N PF02776.18 KXT00828.1 - 1.8e-40 138.4 0.4 6.1e-40 136.6 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KXT00828.1 - 1.1e-35 122.4 0.0 2.3e-35 121.3 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KXT00828.1 - 2.3e-20 72.9 1.6 1e-19 70.9 2.1 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.16 KXT00828.1 - 0.031 14.0 0.0 0.055 13.2 0.0 1.3 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Eclosion PF04736.12 KXT00829.1 - 0.78 9.5 5.6 0.5 10.1 0.5 2.2 1 1 0 2 2 2 0 Eclosion hormone Peptidase_M35 PF02102.15 KXT00836.1 - 1.1e-81 274.5 22.4 5.8e-80 268.9 15.0 2.0 1 1 1 2 2 2 2 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 KXT00836.1 - 1.2e-39 136.2 8.2 2.3e-39 135.2 8.2 1.5 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase RB_A PF01858.17 KXT00836.1 - 0.0011 18.9 0.0 0.0017 18.2 0.0 1.3 1 0 0 1 1 1 1 Retinoblastoma-associated protein A domain Glyco_hydro_2_C PF02836.17 KXT00838.1 - 0.017 14.2 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Abhydrolase_1 PF00561.20 KXT00839.1 - 0.00069 19.3 0.2 0.0016 18.1 0.2 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Mannosyl_trans3 PF11051.8 KXT00840.1 - 0.0084 15.5 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Glyco_transf_8 PF01501.20 KXT00840.1 - 0.013 15.1 3.2 0.24 10.9 3.2 2.2 1 1 0 1 1 1 0 Glycosyl transferase family 8 Amidase PF01425.21 KXT00841.1 - 3.2e-26 92.3 0.3 4.9e-26 91.7 0.3 1.2 1 0 0 1 1 1 1 Amidase Lactamase_B_6 PF16661.5 KXT00842.1 - 1e-62 211.1 0.0 1.6e-62 210.4 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 KXT00842.1 - 4.3e-46 157.2 0.5 4.3e-46 157.2 0.5 3.2 2 1 1 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 KXT00842.1 - 1.3e-16 60.8 0.1 4.9e-16 59.0 0.1 2.1 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 KXT00842.1 - 5.5e-12 45.5 0.0 1.8e-11 43.8 0.0 1.9 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 KXT00842.1 - 0.0018 18.3 1.6 0.0038 17.3 0.0 2.4 3 0 0 3 3 3 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXT00842.1 - 0.0089 15.6 0.1 0.03 13.8 0.1 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Polysacc_deac_1 PF01522.21 KXT00843.1 - 2.1e-17 63.1 0.0 3.4e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 KXT00843.1 - 1.2e-05 25.0 0.7 6.8e-05 22.6 0.4 2.2 2 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.9 KXT00843.1 - 0.0016 16.9 0.0 0.0022 16.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein conserved in bacteria (DUF2194) TPR_12 PF13424.6 KXT00844.1 - 4.1e-13 49.4 8.7 1.2e-06 28.7 1.2 4.9 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 KXT00844.1 - 1.5e-06 27.9 7.3 0.0053 16.6 0.0 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXT00844.1 - 2e-06 27.5 0.1 0.64 10.3 0.0 4.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXT00844.1 - 0.00014 21.5 0.0 0.13 12.1 0.0 3.4 2 0 0 2 2 2 1 Tetratricopeptide repeat AAA_16 PF13191.6 KXT00844.1 - 0.00039 20.9 0.2 0.0016 18.8 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 KXT00844.1 - 0.00043 19.5 0.0 0.00086 18.6 0.0 1.5 1 1 0 1 1 1 1 NB-ARC domain PGAP1 PF07819.13 KXT00844.1 - 0.003 17.3 0.0 0.006 16.3 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein SpoIID PF08486.10 KXT00844.1 - 0.0052 17.3 0.0 0.02 15.4 0.0 2.0 1 0 0 1 1 1 1 Stage II sporulation protein AAA_22 PF13401.6 KXT00844.1 - 0.015 15.6 0.0 0.11 12.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KXT00844.1 - 0.022 14.1 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 KaiC TPR_4 PF07721.14 KXT00844.1 - 0.025 15.2 1.2 0.51 11.1 0.0 3.6 3 0 0 3 3 2 0 Tetratricopeptide repeat RuvB_N PF05496.12 KXT00844.1 - 0.035 13.9 0.0 0.12 12.1 0.0 2.0 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain DUF87 PF01935.17 KXT00844.1 - 0.056 13.5 0.6 5.2 7.1 0.0 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain Acetyltransf_3 PF13302.7 KXT00847.1 - 6.8e-26 91.6 0.0 8.3e-26 91.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXT00847.1 - 5.9e-07 29.7 0.0 1.1e-06 28.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXT00847.1 - 0.00084 19.7 0.0 0.0013 19.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PepSY_2 PF13670.6 KXT00848.1 - 0.11 12.5 0.2 0.24 11.4 0.2 1.6 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain WD40 PF00400.32 KXT00849.1 - 2e-39 132.9 35.1 0.00013 22.6 1.7 10.9 11 0 0 11 11 11 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXT00849.1 - 1.2e-19 70.4 6.7 9.5e-06 25.8 0.0 7.6 4 4 4 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 KXT00849.1 - 4.5e-06 26.7 0.0 0.0012 18.8 0.0 3.9 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Ge1_WD40 PF16529.5 KXT00849.1 - 6e-05 22.1 6.3 3.2 6.6 0.0 5.7 4 2 1 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KXT00849.1 - 9.6e-05 22.2 7.0 2.6 8.1 0.0 6.1 7 0 0 7 7 7 2 WD40-like Beta Propeller Repeat PQQ_3 PF13570.6 KXT00849.1 - 0.00043 20.7 15.3 0.28 11.7 0.1 6.6 7 1 0 7 7 7 2 PQQ-like domain Hira PF07569.11 KXT00849.1 - 0.028 14.1 0.1 0.067 12.9 0.1 1.7 1 0 0 1 1 1 0 TUP1-like enhancer of split VID27 PF08553.10 KXT00849.1 - 0.11 11.6 0.5 3.2 6.7 0.0 2.5 3 0 0 3 3 3 0 VID27 C-terminal WD40-like domain Nup160 PF11715.8 KXT00849.1 - 0.11 11.2 0.1 3 6.4 0.0 2.2 1 1 1 2 2 2 0 Nucleoporin Nup120/160 IKI3 PF04762.12 KXT00849.1 - 0.28 9.1 0.7 0.71 7.8 0.0 1.8 2 0 0 2 2 2 0 IKI3 family Acylphosphatase PF00708.18 KXT00851.1 - 8.1e-24 83.8 0.5 9.2e-24 83.7 0.5 1.0 1 0 0 1 1 1 1 Acylphosphatase DLH PF01738.18 KXT00853.1 - 4.5e-14 52.5 0.0 5.4e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Glutaredoxin2_C PF04399.13 KXT00853.1 - 0.05 13.4 0.1 0.089 12.6 0.1 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Hydrolase_4 PF12146.8 KXT00853.1 - 0.067 12.4 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Aldo_ket_red PF00248.21 KXT00854.1 - 1e-40 139.8 0.1 1.8e-40 139.0 0.0 1.4 2 0 0 2 2 2 1 Aldo/keto reductase family DUF575 PF04746.12 KXT00854.1 - 0.003 17.8 0.0 0.0066 16.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF575) PorB PF11565.8 KXT00855.1 - 0.0027 18.1 0.0 0.48 10.9 0.0 2.3 2 1 0 2 2 2 2 Alpha helical Porin B SnoaL_2 PF12680.7 KXT00855.1 - 0.0037 17.9 0.0 0.0045 17.6 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain Baculo_8kDa PF06096.11 KXT00855.1 - 0.12 12.5 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 Baculoviridae 8.2 KDa protein F-box PF00646.33 KXT00856.1 - 0.0064 16.3 0.0 0.017 15.0 0.0 1.7 1 0 0 1 1 1 1 F-box domain AOX PF01786.17 KXT00857.1 - 2.2e-97 324.9 0.5 2.7e-97 324.6 0.5 1.1 1 0 0 1 1 1 1 Alternative oxidase DUF1358 PF07096.11 KXT00857.1 - 0.13 12.3 0.0 0.46 10.5 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1358) Zn_clus PF00172.18 KXT00858.1 - 0.00014 21.9 12.3 0.00029 20.9 12.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXT00858.1 - 0.00016 20.8 0.1 0.00049 19.2 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain HTH_50 PF18024.1 KXT00858.1 - 0.037 13.6 0.0 0.083 12.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain AA_permease PF00324.21 KXT00859.1 - 4.8e-116 388.2 45.8 6e-116 387.9 45.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXT00859.1 - 8e-33 113.9 46.0 8e-33 113.9 46.0 1.5 2 0 0 2 2 2 1 Amino acid permease AA_permease PF00324.21 KXT00860.1 - 2.3e-116 389.2 45.8 2.7e-116 389.0 45.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXT00860.1 - 2.8e-33 115.4 46.0 3.7e-33 115.0 46.0 1.0 1 0 0 1 1 1 1 Amino acid permease Zn_clus PF00172.18 KXT00861.1 - 0.00014 21.9 12.3 0.00029 20.9 12.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXT00861.1 - 0.00016 20.8 0.1 0.00049 19.2 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain HTH_50 PF18024.1 KXT00861.1 - 0.037 13.6 0.0 0.083 12.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain DWNN PF08783.11 KXT00863.1 - 1.9e-26 92.1 0.4 3.8e-26 91.2 0.4 1.5 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 KXT00863.1 - 3.3e-08 33.2 6.5 6.4e-08 32.3 6.5 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-RING_2 PF13639.6 KXT00863.1 - 0.00099 19.4 7.3 0.0022 18.3 7.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KXT00863.1 - 0.0013 18.5 5.9 0.0013 18.5 5.9 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC PF00098.23 KXT00863.1 - 0.003 17.6 1.0 0.003 17.6 1.0 2.2 2 0 0 2 2 2 1 Zinc knuckle DUF1272 PF06906.11 KXT00863.1 - 0.028 14.5 4.1 0.062 13.4 4.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-C3HC4 PF00097.25 KXT00863.1 - 0.14 12.1 9.2 0.31 11.0 9.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXT00863.1 - 0.17 11.9 5.7 0.37 10.9 5.7 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KXT00863.1 - 0.6 10.3 7.5 1.9 8.7 7.5 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KXT00863.1 - 1.7 8.5 16.4 0.026 14.4 9.1 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) SOG2 PF10428.9 KXT00863.1 - 5.9 6.0 18.6 0.0085 15.3 6.4 2.2 3 0 0 3 3 3 0 RAM signalling pathway protein DUF4551 PF15087.6 KXT00863.1 - 8.8 5.0 8.5 16 4.1 8.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) ADH_N PF08240.12 KXT00864.1 - 5.4e-24 84.2 3.7 8.2e-24 83.6 3.7 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXT00864.1 - 1.5e-17 63.8 0.0 2.5e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXT00864.1 - 6.4e-07 30.5 0.0 9.9e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KXT00864.1 - 0.0025 17.2 0.1 0.0042 16.5 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TPR_12 PF13424.6 KXT00865.1 - 1.6e-13 50.8 9.1 3.8e-08 33.5 0.1 5.2 4 1 1 5 5 5 3 Tetratricopeptide repeat NB-ARC PF00931.22 KXT00865.1 - 6.3e-09 35.4 0.0 1.9e-08 33.8 0.0 1.7 1 1 0 1 1 1 1 NB-ARC domain TPR_10 PF13374.6 KXT00865.1 - 8.8e-05 22.2 14.2 0.49 10.3 0.3 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat ATPase_2 PF01637.18 KXT00865.1 - 0.0006 19.8 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KXT00865.1 - 0.0014 18.9 0.0 0.031 14.6 0.0 3.0 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.6 KXT00865.1 - 0.0042 17.5 0.0 0.011 16.1 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain TPR_7 PF13176.6 KXT00865.1 - 0.012 15.6 0.4 21 5.4 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXT00865.1 - 0.013 15.5 1.9 0.95 9.7 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat IstB_IS21 PF01695.17 KXT00865.1 - 0.12 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Hpr_kinase_C PF07475.12 KXT00865.1 - 0.17 11.4 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain DUF1771 PF08590.10 KXT00865.1 - 3.2 8.2 6.1 0.61 10.5 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1771) ABC_membrane PF00664.23 KXT00866.1 - 6.5e-38 131.0 10.0 8.3e-38 130.6 10.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KXT00866.1 - 4.6e-34 117.9 0.2 1.1e-33 116.7 0.0 1.7 2 0 0 2 2 1 1 ABC transporter SMC_N PF02463.19 KXT00866.1 - 2.2e-07 30.5 0.2 4e-05 23.2 0.2 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KXT00866.1 - 0.00034 21.0 0.0 0.00075 19.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXT00866.1 - 0.00066 20.0 0.1 0.006 16.9 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 KXT00866.1 - 0.00095 19.1 0.2 0.0092 15.8 0.0 2.1 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 KXT00866.1 - 0.0012 18.7 0.1 0.0028 17.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KXT00866.1 - 0.0036 17.1 0.0 0.011 15.5 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KXT00866.1 - 0.0045 17.4 0.0 0.025 15.0 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KXT00866.1 - 0.0046 17.0 0.0 0.088 12.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KXT00866.1 - 0.015 15.2 0.0 0.037 13.9 0.0 1.6 1 1 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 KXT00866.1 - 0.02 14.6 0.0 0.049 13.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KXT00866.1 - 0.02 14.9 0.0 0.059 13.5 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase Rad17 PF03215.15 KXT00866.1 - 0.024 14.6 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_23 PF13476.6 KXT00866.1 - 0.037 14.5 2.0 0.046 14.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KXT00866.1 - 0.039 14.2 0.0 0.097 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KXT00866.1 - 0.065 12.9 0.1 0.52 10.0 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KXT00866.1 - 0.07 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 KXT00866.1 - 0.083 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 KXT00866.1 - 0.086 12.0 0.0 0.49 9.5 0.0 2.0 2 0 0 2 2 2 0 G-protein alpha subunit AAA_18 PF13238.6 KXT00866.1 - 0.13 12.8 0.0 0.41 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain PRP1_N PF06424.12 KXT00867.1 - 1e-46 159.0 10.8 6e-46 156.5 10.8 2.4 1 1 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_19 PF14559.6 KXT00867.1 - 1e-20 74.0 7.5 6.6e-05 23.3 0.3 9.8 7 3 2 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.6 KXT00867.1 - 2.6e-20 71.4 35.6 0.00031 21.3 0.1 14.4 6 5 10 16 16 14 6 Tetratricopeptide repeat TPR_2 PF07719.17 KXT00867.1 - 9e-13 47.3 0.9 1.4 9.2 0.0 10.0 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_8 PF13181.6 KXT00867.1 - 5.1e-09 35.7 1.1 0.091 13.0 0.0 7.7 9 0 0 9 9 7 2 Tetratricopeptide repeat NARP1 PF12569.8 KXT00867.1 - 1.3e-06 27.7 5.4 0.3 10.0 0.0 5.5 4 1 1 6 6 6 2 NMDA receptor-regulated protein 1 TPR_15 PF13429.6 KXT00867.1 - 3e-06 26.7 20.4 0.0029 16.9 2.7 5.9 4 2 1 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 KXT00867.1 - 4.5e-06 26.7 0.1 1.5e+02 3.1 0.0 9.5 11 1 1 12 12 11 0 Tetratricopeptide repeat TPR_9 PF13371.6 KXT00867.1 - 5.7e-05 23.2 0.1 1.1 9.4 0.0 5.2 4 1 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXT00867.1 - 0.00023 21.7 18.4 1.9 9.2 0.0 7.3 7 1 0 7 7 7 2 Tetratricopeptide repeat Suf PF05843.14 KXT00867.1 - 0.00043 20.4 4.5 0.17 11.9 0.0 4.5 5 0 0 5 5 5 1 Suppressor of forked protein (Suf) TPR_1 PF00515.28 KXT00867.1 - 0.0013 18.4 0.0 6 6.9 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXT00867.1 - 0.0076 15.9 0.3 5.5 6.8 0.0 4.9 6 0 0 6 6 6 1 TPR repeat PIN PF01850.21 KXT00867.1 - 1.1 9.7 10.9 0.13 12.8 0.6 3.9 3 1 2 5 5 5 0 PIN domain TPR_6 PF13174.6 KXT00867.1 - 1.5 9.6 14.9 56 4.7 0.0 8.5 11 0 0 11 11 10 0 Tetratricopeptide repeat PD-C2-AF1 PF09310.10 KXT00869.1 - 0.019 14.4 0.5 0.024 14.0 0.5 1.2 1 0 0 1 1 1 0 POU domain, class 2, associating factor 1 HET PF06985.11 KXT00870.1 - 2.1e-28 99.5 0.0 4.3e-28 98.5 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MatE PF01554.18 KXT00872.1 - 7.3e-39 133.0 27.3 6e-28 97.5 7.4 2.5 3 0 0 3 3 3 2 MatE CorA PF01544.18 KXT00873.1 - 9e-13 48.2 0.0 1.6e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF4398 PF14346.6 KXT00873.1 - 4.2 8.1 6.0 7.9 7.2 6.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) AIM24 PF01987.17 KXT00874.1 - 5.8e-48 163.4 0.0 7.6e-48 163.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 RebB PF11747.8 KXT00874.1 - 0.031 14.4 0.3 0.071 13.2 0.3 1.6 1 0 0 1 1 1 0 Killing trait TFIID_20kDa PF03847.13 KXT00875.1 - 2e-19 69.8 0.0 4e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 KXT00875.1 - 0.084 13.2 0.0 0.22 11.8 0.0 1.8 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Cu-oxidase PF00394.22 KXT00877.1 - 2.5e-28 99.2 0.0 5.7e-28 98.0 0.0 1.6 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 KXT00877.1 - 2.3e-27 95.3 1.0 3.9e-27 94.6 0.1 1.9 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KXT00877.1 - 1.1e-23 83.4 3.5 5.7e-20 71.5 0.1 3.5 3 1 0 3 3 3 2 Multicopper oxidase DUF3390 PF11870.8 KXT00877.1 - 0.024 15.0 0.5 0.099 13.0 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3390) CorA PF01544.18 KXT00879.1 - 8.8e-12 44.9 0.1 1.4e-11 44.3 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein HpcH_HpaI PF03328.14 KXT00879.1 - 0.077 12.1 0.0 5.1 6.2 0.0 2.3 2 0 0 2 2 2 0 HpcH/HpaI aldolase/citrate lyase family FliJ PF02050.16 KXT00879.1 - 7.9 6.7 7.6 1.6 9.0 3.2 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein Nucleotid_trans PF03407.16 KXT00880.1 - 2.8e-20 73.2 0.1 6.3e-20 72.1 0.0 1.5 2 0 0 2 2 2 1 Nucleotide-diphospho-sugar transferase Put_DNA-bind_N PF06971.13 KXT00880.1 - 0.07 13.1 0.1 0.17 11.9 0.1 1.6 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus Indigoidine_A PF04227.12 KXT00881.1 - 2.7e-121 404.4 1.8 3.9e-121 403.9 1.8 1.2 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 KXT00881.1 - 2.2e-21 76.5 0.0 2.1e-10 40.4 0.0 2.4 2 0 0 2 2 2 2 pfkB family carbohydrate kinase RRM_1 PF00076.22 KXT00896.1 - 1.8e-68 226.3 3.2 1.2e-18 66.7 0.0 5.9 6 0 0 6 6 6 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KXT00896.1 - 6.8e-07 29.2 0.0 0.22 11.5 0.0 4.0 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KXT00896.1 - 1.3e-06 28.4 0.0 0.052 13.7 0.0 4.5 5 0 0 5 5 5 2 RNA recognition motif RRM_occluded PF16842.5 KXT00896.1 - 3.9e-05 23.4 0.0 1.6 8.7 0.0 4.2 5 0 0 5 5 5 2 Occluded RNA-recognition motif Limkain-b1 PF11608.8 KXT00896.1 - 9.5e-05 22.4 0.7 0.53 10.4 0.0 5.2 5 2 0 5 5 5 1 Limkain b1 Nup35_RRM PF05172.13 KXT00896.1 - 0.0015 18.4 0.0 0.67 9.9 0.0 2.6 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 KXT00896.1 - 0.002 17.7 0.0 16 5.1 0.0 4.3 3 1 1 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Neuregulin PF02158.15 KXT00896.1 - 3 7.1 8.2 0.9 8.8 2.3 2.3 1 1 1 2 2 2 0 Neuregulin intracellular region TEA PF01285.18 KXT00897.1 - 1.5e-26 92.2 0.1 3.3e-26 91.1 0.1 1.6 1 0 0 1 1 1 1 TEA/ATTS domain TMEM71 PF15121.6 KXT00897.1 - 0.16 11.7 0.7 0.36 10.5 0.1 1.9 2 0 0 2 2 2 0 TMEM71 protein family TEA PF01285.18 KXT00898.1 - 1.5e-26 92.2 0.1 3.3e-26 91.1 0.1 1.6 1 0 0 1 1 1 1 TEA/ATTS domain TMEM71 PF15121.6 KXT00898.1 - 0.16 11.7 0.7 0.36 10.5 0.1 1.9 2 0 0 2 2 2 0 TMEM71 protein family Pyr_redox_2 PF07992.14 KXT00899.1 - 6e-53 180.0 3.9 7.9e-53 179.6 3.9 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 KXT00899.1 - 4e-16 58.7 0.0 1.2e-15 57.2 0.0 1.8 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 KXT00899.1 - 4.2e-15 56.1 1.8 4.2e-15 56.1 1.8 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXT00899.1 - 5.8e-08 32.4 0.9 3e-06 26.7 0.1 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 KXT00899.1 - 3.6e-06 26.9 0.0 4.3e-05 23.4 0.0 2.7 4 0 0 4 4 4 1 Rieske-like [2Fe-2S] domain Reductase_C PF14759.6 KXT00899.1 - 0.0013 19.2 0.0 0.0053 17.3 0.0 2.0 2 0 0 2 2 2 1 Reductase C-terminal NAD_binding_9 PF13454.6 KXT00899.1 - 0.0018 18.3 0.0 1 9.3 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 KXT00899.1 - 0.075 12.6 0.8 0.41 10.2 0.1 2.3 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain adh_short_C2 PF13561.6 KXT00900.1 - 9.5e-64 215.1 0.0 1.1e-63 214.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXT00900.1 - 8.9e-46 155.8 0.1 1.1e-45 155.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXT00900.1 - 3.5e-11 43.4 0.1 5.3e-11 42.8 0.1 1.2 1 0 0 1 1 1 1 KR domain FolB PF02152.18 KXT00902.1 - 2.9e-25 89.0 0.0 3.1e-18 66.3 0.1 2.2 2 0 0 2 2 2 2 Dihydroneopterin aldolase Sugar_tr PF00083.24 KXT00903.1 - 1.5e-70 238.3 30.2 4e-46 157.8 9.3 2.7 2 1 1 3 3 3 2 Sugar (and other) transporter CDH-cyt PF16010.5 KXT00903.1 - 9.2e-26 90.6 1.1 1.8e-25 89.7 1.1 1.3 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase MFS_1 PF07690.16 KXT00903.1 - 5.3e-14 51.9 39.0 2.6e-10 39.8 11.0 4.2 3 2 0 4 4 4 2 Major Facilitator Superfamily DOMON PF03351.17 KXT00903.1 - 9.4e-05 22.6 0.1 0.00021 21.5 0.1 1.5 1 0 0 1 1 1 1 DOMON domain DUF2427 PF10348.9 KXT00903.1 - 0.00065 19.5 2.1 0.0029 17.4 2.1 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) DUF4079 PF13301.6 KXT00903.1 - 1.5 8.9 7.3 1.7 8.8 2.6 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) RRP7 PF12923.7 KXT00904.1 - 1e-33 116.0 14.8 1.8e-33 115.2 14.8 1.4 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 KXT00904.1 - 3.9e-20 72.3 0.0 1e-19 70.9 0.0 1.7 1 1 0 1 1 1 1 Rrp7 RRM-like N-terminal domain DUF4407 PF14362.6 KXT00904.1 - 0.023 14.0 4.2 0.031 13.6 4.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HET PF06985.11 KXT00905.1 - 1.8e-26 93.2 0.0 1.5e-25 90.3 0.0 2.4 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) FAD_binding_8 PF08022.12 KXT00906.1 - 6.9e-23 80.8 0.0 1.5e-22 79.7 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KXT00906.1 - 1.1e-21 77.6 0.0 1.8e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KXT00906.1 - 5.3e-19 68.6 8.0 5.3e-19 68.6 8.0 2.3 1 1 1 2 2 2 1 Ferric reductase like transmembrane component DNA_pol3_a_NII PF11490.8 KXT00907.1 - 0.77 9.7 6.8 1.2 9.0 6.8 1.3 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II RR_TM4-6 PF06459.12 KXT00907.1 - 1.3 8.7 10.2 2.5 7.9 10.2 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Borrelia_P83 PF05262.11 KXT00907.1 - 2 6.8 9.7 2.9 6.3 9.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein PPL5 PF18168.1 KXT00907.1 - 2.1 7.6 6.5 3.4 6.9 6.5 1.2 1 0 0 1 1 1 0 Prim-pol family 5 RNA_polI_A34 PF08208.11 KXT00907.1 - 6.7 6.7 21.6 5 7.2 17.2 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Presenilin PF01080.17 KXT00907.1 - 9.8 4.8 8.7 13 4.4 8.7 1.3 1 0 0 1 1 1 0 Presenilin FAD_binding_4 PF01565.23 KXT00908.1 - 2.7e-17 62.8 0.0 5.7e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXT00908.1 - 2.5e-06 27.5 0.4 6.7e-06 26.1 0.4 1.7 1 0 0 1 1 1 1 Berberine and berberine like ALO PF04030.14 KXT00908.1 - 0.002 18.0 0.1 0.0045 16.8 0.1 1.5 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase Cytokin-bind PF09265.10 KXT00908.1 - 0.061 12.7 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding EPSP_synthase PF00275.20 KXT00909.1 - 1.5e-121 406.0 0.0 2.2e-121 405.4 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 KXT00909.1 - 9e-100 333.2 0.0 1.6e-99 332.3 0.0 1.4 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 KXT00909.1 - 3.9e-58 197.4 0.0 7.6e-58 196.5 0.0 1.5 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 KXT00909.1 - 3.8e-37 127.9 0.0 2.8e-36 125.0 0.0 2.2 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 KXT00909.1 - 2.4e-23 82.2 0.0 6.8e-23 80.7 0.0 1.9 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.6 KXT00909.1 - 1.5e-06 28.1 0.0 4e-06 26.7 0.0 1.6 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase SDH_C PF18317.1 KXT00909.1 - 1.6e-05 24.6 0.1 3.6e-05 23.4 0.1 1.7 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 KXT00909.1 - 0.065 13.3 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase RTC PF01137.21 KXT00909.1 - 0.086 12.0 0.3 0.92 8.7 0.3 2.7 2 1 1 3 3 3 0 RNA 3'-terminal phosphate cyclase AAA_18 PF13238.6 KXT00909.1 - 0.096 13.2 0.0 4.4 7.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain TRI12 PF06609.13 KXT00913.1 - 6.2e-05 21.6 2.7 8.4e-05 21.2 2.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_76 PF03663.14 KXT00914.1 - 4.7e-28 98.7 0.5 5.5e-28 98.5 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyoxalase_4 PF13669.6 KXT00915.1 - 0.14 12.4 0.0 0.18 12.1 0.0 1.1 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily TRAM_LAG1_CLN8 PF03798.16 KXT00917.1 - 3.4e-46 157.5 12.2 5.5e-46 156.8 12.2 1.3 1 0 0 1 1 1 1 TLC domain DHDPS PF00701.22 KXT00918.1 - 4.7e-27 94.4 0.0 6.1e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Ribosomal_S15 PF00312.22 KXT00919.1 - 2.6e-23 82.0 0.1 7.1e-23 80.6 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S15 SBF PF01758.16 KXT00920.1 - 1e-47 162.4 5.9 1e-47 162.4 5.9 2.5 3 0 0 3 3 3 1 Sodium Bile acid symporter family Rav1p_C PF12234.8 KXT00921.1 - 7.7e-144 480.5 1.6 2.3e-143 479.0 1.6 1.7 1 1 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.32 KXT00921.1 - 0.0034 18.2 0.1 0.93 10.5 0.0 4.0 3 1 0 3 3 3 1 WD domain, G-beta repeat Acyl-CoA_dh_1 PF00441.24 KXT00923.1 - 4.7e-30 104.8 1.2 8.2e-30 104.0 1.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KXT00923.1 - 1.3e-21 76.6 0.0 2.3e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KXT00923.1 - 5.6e-20 72.1 0.2 1.3e-19 71.0 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KXT00923.1 - 2.8e-16 60.0 2.1 1.7e-15 57.5 0.6 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Cpn60_TCP1 PF00118.24 KXT00925.1 - 4.2e-172 573.2 1.9 4.7e-172 573.0 1.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family BRK PF07533.16 KXT00925.1 - 0.068 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 BRK domain Zn_clus PF00172.18 KXT00926.1 - 4.6e-05 23.5 6.8 4.6e-05 23.5 6.8 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dynein_light PF01221.18 KXT00927.1 - 7.4e-39 132.0 2.0 8.8e-39 131.7 2.0 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 RhoGEF67_u1 PF16615.5 KXT00927.1 - 0.15 12.6 0.1 0.21 12.1 0.1 1.2 1 0 0 1 1 1 0 Unstructured region one on RhoGEF 6 and 7 DEAD PF00270.29 KXT00929.1 - 9.2e-31 107.0 0.0 1.6e-30 106.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXT00929.1 - 7e-25 87.5 0.0 7.2e-24 84.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXT00929.1 - 2e-05 24.6 0.0 4e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Amidohydro_2 PF04909.14 KXT00931.1 - 2.7e-21 76.6 1.9 8.3e-21 75.0 1.9 1.9 1 1 0 1 1 1 1 Amidohydrolase ATP-synt_G PF04718.15 KXT00934.1 - 1.9e-33 115.3 0.3 5.9e-33 113.7 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit DUF883 PF05957.13 KXT00934.1 - 0.034 14.8 2.6 0.23 12.1 2.0 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Alanine_zipper PF11839.8 KXT00934.1 - 9 6.7 20.8 20 5.7 0.2 2.6 2 1 1 3 3 3 0 Alanine-zipper, major outer membrane lipoprotein zf-Tim10_DDP PF02953.15 KXT00935.1 - 1.3e-21 76.0 0.8 1.5e-21 75.8 0.8 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Tom5 PF10642.9 KXT00935.1 - 0.22 11.6 0.4 0.22 11.6 0.4 2.7 3 0 0 3 3 3 0 Mitochondrial import receptor subunit or translocase TMEM223 PF14640.6 KXT00936.1 - 0.0043 17.2 0.5 0.017 15.3 0.1 1.8 1 1 0 2 2 2 1 Transmembrane protein 223 Glyco_tranf_2_3 PF13641.6 KXT00937.1 - 4.5e-30 105.2 0.1 5.9e-30 104.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KXT00937.1 - 2e-07 30.6 0.1 6.3e-07 29.0 0.1 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KXT00937.1 - 8.5e-07 28.9 0.0 2.5e-06 27.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 Chitin_synth_2 PF03142.15 KXT00937.1 - 0.54 8.8 4.3 0.78 8.3 4.3 1.3 1 1 0 1 1 1 0 Chitin synthase INCENP_ARK-bind PF03941.15 KXT00941.1 - 2.2e-17 62.8 1.0 2.2e-17 62.8 1.0 2.5 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region IU_nuc_hydro PF01156.19 KXT00946.1 - 1.1e-12 48.2 4.1 3.6e-10 39.9 0.0 2.3 1 1 1 2 2 2 2 Inosine-uridine preferring nucleoside hydrolase zf-Dof PF02701.15 KXT00946.1 - 0.051 13.7 0.2 0.11 12.7 0.2 1.5 1 0 0 1 1 1 0 Dof domain, zinc finger zf-C3HC4_2 PF13923.6 KXT00947.1 - 6.8e-11 41.8 11.7 1.2e-10 41.0 11.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXT00947.1 - 3.9e-10 39.9 11.7 6.8e-10 39.1 11.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KXT00947.1 - 7.1e-09 35.4 12.4 1.1e-08 34.7 12.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXT00947.1 - 2.7e-07 30.4 9.7 5e-07 29.5 9.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXT00947.1 - 2.7e-07 30.5 7.5 6e-07 29.4 7.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 KXT00947.1 - 3.3e-06 27.3 8.4 7.8e-06 26.1 8.4 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KXT00947.1 - 2.9e-05 23.9 11.8 5.3e-05 23.1 11.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KXT00947.1 - 4.7e-05 23.2 8.6 9.1e-05 22.2 8.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KXT00947.1 - 0.00018 21.6 10.6 0.0003 20.9 10.6 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 KXT00947.1 - 0.0023 17.9 7.6 0.0083 16.2 7.6 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 KXT00947.1 - 0.0051 16.5 3.1 0.011 15.5 3.1 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_4 PF14570.6 KXT00947.1 - 0.014 15.1 10.3 0.028 14.2 10.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 KXT00947.1 - 0.019 14.8 5.4 0.037 13.9 5.4 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 KXT00947.1 - 0.045 13.9 7.8 0.11 12.6 7.8 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-Nse PF11789.8 KXT00947.1 - 0.059 13.2 5.5 0.1 12.5 5.5 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF4407 PF14362.6 KXT00948.1 - 0.92 8.8 15.2 2.3 7.5 15.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Peptidase_M20 PF01546.28 KXT00949.1 - 1.4e-27 96.8 0.1 1.9e-27 96.3 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KXT00949.1 - 4.1e-17 62.1 0.0 9.1e-17 61.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Y_phosphatase3 PF13350.6 KXT00950.1 - 5.2e-41 141.1 0.0 9.4e-41 140.3 0.0 1.3 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 KXT00950.1 - 3.5e-09 36.4 0.2 2.9e-07 30.2 0.0 2.9 2 1 1 3 3 3 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KXT00950.1 - 0.00088 18.9 0.0 0.0019 17.8 0.0 1.5 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Myotub-related PF06602.14 KXT00950.1 - 0.079 11.9 0.0 0.44 9.4 0.0 1.9 2 0 0 2 2 2 0 Myotubularin-like phosphatase domain DSPc PF00782.20 KXT00950.1 - 0.14 12.0 0.0 1.2 9.0 0.0 2.1 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain MGC-24 PF05283.11 KXT00951.1 - 8e-05 23.1 5.5 8e-05 23.1 5.5 2.9 1 1 1 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin RNA_pol_L_2 PF13656.6 KXT00954.1 - 1.4e-24 85.6 0.0 2.1e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KXT00954.1 - 5.6e-08 32.1 0.0 1.3e-07 30.9 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Rio2_N PF09202.11 KXT00954.1 - 0.017 15.3 0.0 0.031 14.5 0.0 1.4 1 0 0 1 1 1 0 Rio2, N-terminal RNA_pol_L_2 PF13656.6 KXT00955.1 - 1.4e-24 85.7 0.0 2e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KXT00955.1 - 5.4e-08 32.2 0.0 1.3e-07 30.9 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Rio2_N PF09202.11 KXT00955.1 - 0.016 15.4 0.0 0.031 14.5 0.0 1.4 1 0 0 1 1 1 0 Rio2, N-terminal Glyco_hydro_47 PF01532.20 KXT00956.1 - 2.8e-167 557.3 1.4 3.5e-167 556.9 1.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Questin_oxidase PF14027.6 KXT00958.1 - 4.8e-99 332.1 0.0 6.5e-99 331.7 0.0 1.2 1 0 0 1 1 1 1 Questin oxidase-like FAD_binding_6 PF00970.24 KXT00958.1 - 0.066 13.6 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain EXS PF03124.14 KXT00961.1 - 1.4e-86 290.8 17.5 1.6e-86 290.7 17.5 1.0 1 0 0 1 1 1 1 EXS family PIF1 PF05970.14 KXT00962.1 - 1e-35 123.6 0.0 6.4e-26 91.4 0.0 2.3 2 0 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 KXT00962.1 - 2.3e-19 69.9 0.0 1.4e-17 64.0 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KXT00962.1 - 4.8e-08 33.5 0.2 4e-07 30.5 0.1 2.5 2 1 0 2 2 2 1 AAA domain Herpes_Helicase PF02689.14 KXT00962.1 - 1.5e-06 26.5 0.0 1.2e-05 23.5 0.0 2.2 3 0 0 3 3 3 1 Helicase UvrD_C_2 PF13538.6 KXT00962.1 - 1.3e-05 25.0 0.0 2.9e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 KXT00962.1 - 2.1e-05 24.4 0.2 0.12 12.1 0.0 2.8 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 KXT00962.1 - 7.4e-05 22.7 0.7 0.011 15.7 0.7 2.4 1 1 0 1 1 1 1 NTPase AAA_22 PF13401.6 KXT00962.1 - 0.00012 22.4 0.4 0.0009 19.5 0.4 2.2 1 1 0 1 1 1 1 AAA domain AAA_32 PF13654.6 KXT00962.1 - 0.0024 16.7 0.1 0.0036 16.2 0.1 1.2 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 KXT00962.1 - 0.0025 16.9 0.0 0.0041 16.1 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA PF00004.29 KXT00962.1 - 0.0043 17.5 0.0 0.012 16.1 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KXT00962.1 - 0.0049 16.4 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region PHD PF00628.29 KXT00962.1 - 0.0083 16.0 1.8 0.0083 16.0 1.8 2.3 2 0 0 2 2 2 1 PHD-finger AAA_5 PF07728.14 KXT00962.1 - 0.035 14.1 0.1 0.2 11.7 0.1 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 KXT00962.1 - 0.035 13.3 0.1 0.071 12.3 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain PhoH PF02562.16 KXT00962.1 - 0.037 13.5 0.0 0.11 12.0 0.0 1.8 1 0 0 1 1 1 0 PhoH-like protein Helicase_RecD PF05127.14 KXT00962.1 - 0.08 12.8 0.4 0.76 9.6 0.4 2.2 1 1 0 1 1 1 0 Helicase AAA_33 PF13671.6 KXT00962.1 - 0.11 12.6 0.1 0.29 11.3 0.1 1.7 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KXT00962.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase UvrD-helicase PF00580.21 KXT00962.1 - 0.16 11.4 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_29 PF13555.6 KXT00962.1 - 0.62 9.8 0.0 0.62 9.8 0.0 1.9 2 0 0 2 2 1 0 P-loop containing region of AAA domain PCAF_N PF06466.11 KXT00963.1 - 0.1 12.2 1.5 0.36 10.4 0.1 2.0 1 1 1 2 2 2 0 PCAF (P300/CBP-associated factor) N-terminal domain DUF1633 PF07794.11 KXT00963.1 - 4.5 5.3 7.3 5.9 4.9 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) Methyltransf_3 PF01596.17 KXT00964.1 - 8.8e-11 41.4 0.0 1.2e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 KXT00964.1 - 2.1e-10 41.5 0.0 4.1e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF2797 PF10977.8 KXT00964.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2797) Prenyltrans PF00432.21 KXT00965.1 - 4e-25 87.3 10.5 1e-06 28.4 0.1 5.7 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 KXT00965.1 - 1.3e-05 24.5 0.0 2.5e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 KXT00965.1 - 0.0014 17.8 0.0 1.6 7.7 0.0 3.1 3 0 0 3 3 3 1 Squalene-hopene cyclase N-terminal domain TED_complement PF07678.14 KXT00965.1 - 0.031 13.3 0.1 0.31 10.0 0.1 2.0 1 1 0 1 1 1 0 A-macroglobulin TED domain DUF3314 PF11771.8 KXT00965.1 - 0.035 14.2 0.1 0.15 12.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3314) Sulfotransfer_4 PF17784.1 KXT00967.1 - 4.5e-18 65.9 0.0 5.3e-18 65.6 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain DUF2606 PF10794.9 KXT00968.1 - 0.006 16.4 0.1 0.016 14.9 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2606) Sigma70_r4 PF04545.16 KXT00968.1 - 0.013 15.0 0.0 0.04 13.5 0.0 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_IclR PF09339.10 KXT00968.1 - 0.028 14.2 0.0 0.051 13.4 0.0 1.3 1 0 0 1 1 1 0 IclR helix-turn-helix domain Sigma70_r4_2 PF08281.12 KXT00968.1 - 0.052 13.2 0.0 0.24 11.1 0.0 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_23 PF13384.6 KXT00968.1 - 0.17 11.7 0.0 1.9 8.4 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain TruB_C_2 PF16198.5 KXT00970.1 - 0.044 13.9 0.1 0.19 11.9 0.0 2.0 2 0 0 2 2 2 0 tRNA pseudouridylate synthase B C-terminal domain P5CR_dimer PF14748.6 KXT00971.1 - 8.7e-13 48.4 4.6 8.7e-13 48.4 4.6 1.7 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KXT00971.1 - 1.6e-07 31.8 0.0 4e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent PGDH_C PF16896.5 KXT00971.1 - 0.043 13.7 0.1 0.067 13.1 0.1 1.3 1 0 0 1 1 1 0 Phosphogluconate dehydrogenase (decarboxylating) C-term ABC2_membrane_5 PF13346.6 KXT00972.1 - 7.3 6.1 10.3 1.5 8.3 0.1 3.0 3 0 0 3 3 3 0 ABC-2 family transporter protein NMO PF03060.15 KXT00973.1 - 2.4e-27 96.2 7.4 2.1e-24 86.5 7.4 2.2 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.18 KXT00973.1 - 1e-07 31.3 0.4 1.6e-07 30.7 0.4 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KXT00973.1 - 3.7e-07 29.5 1.5 6.1e-07 28.8 0.1 1.9 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KXT00973.1 - 1.2e-06 28.0 0.2 1.9e-06 27.3 0.2 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.21 KXT00973.1 - 0.085 12.1 0.1 0.15 11.3 0.1 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase DAP3 PF10236.9 KXT00975.1 - 5.7e-90 301.6 0.0 7.1e-90 301.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 Sod_Fe_C PF02777.18 KXT00976.1 - 1.8e-17 63.4 0.1 3.1e-09 36.9 0.0 2.6 3 0 0 3 3 3 2 Iron/manganese superoxide dismutases, C-terminal domain Telomerase_RBD PF12009.8 KXT00977.1 - 3.4e-45 153.5 0.3 8.8e-45 152.1 0.1 1.9 2 0 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 KXT00977.1 - 3.8e-14 52.7 0.0 1.9e-10 40.6 0.0 2.6 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_L38e PF01781.18 KXT00978.1 - 1.6e-34 117.8 1.5 2.1e-34 117.4 1.5 1.2 1 0 0 1 1 1 1 Ribosomal L38e protein family EF-hand_4 PF12763.7 KXT00979.1 - 3.1e-27 94.6 0.0 1.3e-13 50.8 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand WH2 PF02205.20 KXT00979.1 - 1.6e-06 27.7 2.8 2.2e-06 27.3 0.8 2.2 2 0 0 2 2 2 1 WH2 motif EF-hand_7 PF13499.6 KXT00979.1 - 9.3e-06 26.0 1.3 0.007 16.8 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain pair DUF1720 PF08226.11 KXT00979.1 - 2.3e-05 24.7 70.2 8.2e-05 22.9 30.8 7.2 5 2 2 7 7 7 3 Domain of unknown function (DUF1720) EF-hand_1 PF00036.32 KXT00979.1 - 0.0012 18.2 0.0 0.92 9.2 0.0 3.2 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KXT00979.1 - 0.13 12.1 0.9 12 5.8 0.0 3.3 4 0 0 4 4 4 0 EF-hand domain pair EF-hand_6 PF13405.6 KXT00979.1 - 0.13 12.2 0.3 17 5.6 0.1 3.7 4 0 0 4 4 4 0 EF-hand domain Kinesin PF00225.23 KXT00980.1 - 2e-96 322.9 0.0 2e-96 322.9 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KXT00980.1 - 5.8e-23 81.5 0.0 1.5e-22 80.1 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding PKcGMP_CC PF16808.5 KXT00980.1 - 0.39 10.6 12.4 0.78 9.6 4.0 3.8 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Eisosome1 PF12757.7 KXT00981.1 - 1.4e-34 119.0 19.5 1.4e-34 119.0 19.5 4.5 5 0 0 5 5 5 1 Eisosome protein 1 SNF2_N PF00176.23 KXT00986.1 - 7.9e-66 222.1 0.0 1.5e-65 221.2 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_2 PF13923.6 KXT00986.1 - 4.2e-10 39.3 9.9 9.6e-10 38.2 9.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXT00986.1 - 3.8e-09 36.7 10.8 7.2e-09 35.8 10.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KXT00986.1 - 6.4e-09 35.5 7.3 1.4e-08 34.4 7.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXT00986.1 - 1.8e-08 34.1 10.0 3.4e-08 33.2 10.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXT00986.1 - 3.5e-07 30.2 7.3 7.6e-07 29.1 7.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KXT00986.1 - 4.7e-07 29.5 8.3 9.5e-07 28.6 8.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KXT00986.1 - 3.9e-06 26.7 10.8 7.8e-06 25.8 10.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KXT00986.1 - 7.4e-06 26.2 7.1 2e-05 24.8 7.1 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain Helicase_C PF00271.31 KXT00986.1 - 0.001 19.4 0.0 0.0056 17.0 0.0 2.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_4 PF15227.6 KXT00986.1 - 0.002 18.2 9.2 0.0044 17.1 9.2 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KXT00986.1 - 0.033 14.0 3.7 0.069 13.0 3.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 KXT00986.1 - 0.087 12.5 4.5 0.18 11.4 4.5 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 KXT00986.1 - 0.2 11.7 3.7 0.43 10.7 3.7 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 KXT00986.1 - 0.58 10.3 5.1 1.3 9.2 5.1 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-P11 PF03854.14 KXT00986.1 - 0.71 9.6 4.5 1.3 8.7 4.5 1.4 1 0 0 1 1 1 0 P-11 zinc finger DUF2262 PF10020.9 KXT00986.1 - 0.91 9.9 3.1 2.6 8.4 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2262) DUF1272 PF06906.11 KXT00986.1 - 1.1 9.4 4.7 2.4 8.3 4.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DUF202 PF02656.15 KXT00992.1 - 1.4e-12 47.9 1.9 1.4e-12 47.9 1.9 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF202) C2-set_2 PF08205.12 KXT00992.1 - 0.029 14.4 0.0 7.8 6.6 0.0 2.3 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain SdpI PF13630.6 KXT00992.1 - 0.09 12.9 0.2 0.15 12.2 0.2 1.4 1 0 0 1 1 1 0 SdpI/YhfL protein family SPT16 PF08644.11 KXT00993.1 - 1.4e-55 187.6 0.2 1.4e-55 187.6 0.2 2.5 3 0 0 3 3 3 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 KXT00993.1 - 2.5e-53 180.2 0.4 2.5e-53 180.2 0.4 2.5 3 0 0 3 3 3 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 KXT00993.1 - 3e-29 102.2 0.0 5.1e-29 101.5 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 KXT00993.1 - 1e-15 57.9 0.1 4.5e-15 55.8 0.0 2.2 2 0 0 2 2 2 1 Histone chaperone Rttp106-like 2H-phosphodiest PF08975.10 KXT00994.1 - 7.6e-21 74.2 0.0 1.1e-20 73.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1868) 2_5_RNA_ligase2 PF13563.6 KXT00994.1 - 0.0024 17.8 0.0 0.0032 17.4 0.0 1.3 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily MMU163 PF17119.5 KXT00995.1 - 1.3e-90 302.9 3.2 2.3e-67 226.8 0.1 2.1 1 1 1 2 2 2 2 Mitochondrial protein up-regulated during meiosis PAN_2 PF08276.11 KXT00995.1 - 0.064 13.4 0.9 0.12 12.5 0.9 1.4 1 0 0 1 1 1 0 PAN-like domain APG6_N PF17675.1 KXT00996.1 - 0.049 14.2 0.7 0.049 14.2 0.7 1.8 2 0 0 2 2 2 0 Apg6 coiled-coil region Cnd2 PF05786.14 KXT00996.1 - 0.13 10.9 6.1 0.16 10.6 6.1 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 SDA1 PF05285.12 KXT00996.1 - 0.34 10.3 8.8 0.49 9.8 8.8 1.3 1 0 0 1 1 1 0 SDA1 PPP4R2 PF09184.11 KXT00996.1 - 3.4 7.2 6.3 4.5 6.8 6.3 1.2 1 0 0 1 1 1 0 PPP4R2 BUD22 PF09073.10 KXT00996.1 - 8.9 5.5 14.0 12 5.2 10.5 2.0 2 0 0 2 2 2 0 BUD22 MBA1 PF07961.11 KXT00997.1 - 7.8e-10 38.2 0.0 1.3e-08 34.3 0.0 2.0 1 1 1 2 2 2 2 MBA1-like protein ATP-synt_E PF05680.12 KXT00998.1 - 1.5 9.2 9.3 5.6 7.4 2.2 2.6 2 0 0 2 2 2 0 ATP synthase E chain Sugar_tr PF00083.24 KXT00999.1 - 2.4e-104 349.7 16.0 2.8e-104 349.5 16.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXT00999.1 - 1.3e-30 106.5 17.4 1.3e-30 106.5 17.4 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KXT00999.1 - 0.001 18.0 7.8 0.027 13.3 0.1 2.4 1 1 1 2 2 2 2 MFS_1 like family DUF2530 PF10745.9 KXT00999.1 - 0.41 10.9 4.2 0.4 11.0 0.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Med3 PF11593.8 KXT01000.1 - 0.063 12.5 0.6 0.073 12.3 0.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ribosomal_S7 PF00177.21 KXT01000.1 - 0.14 11.8 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S7p/S5e SUI1 PF01253.22 KXT01001.1 - 3.5e-28 98.0 3.6 4.5e-28 97.6 3.6 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 GlcNAc-1_reg PF18440.1 KXT01001.1 - 0.097 12.9 0.3 0.15 12.3 0.3 1.2 1 0 0 1 1 1 0 Putative GlcNAc-1 phosphotransferase regulatory domain Abhydrolase_3 PF07859.13 KXT01002.1 - 4.2e-50 170.5 0.0 5.2e-50 170.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXT01002.1 - 1.7e-09 37.1 0.7 9.4e-09 34.7 0.7 1.8 1 1 0 1 1 1 1 Carboxylesterase family DUF382 PF04037.13 KXT01002.1 - 0.024 14.8 0.0 0.042 14.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF382) Peptidase_S9 PF00326.21 KXT01002.1 - 0.036 13.5 0.0 0.078 12.4 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 KXT01002.1 - 0.04 12.8 0.0 0.048 12.5 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase Abhydrolase_1 PF00561.20 KXT01002.1 - 0.12 12.0 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold gpW PF02831.15 KXT01004.1 - 0.083 12.8 0.1 0.083 12.8 0.1 2.6 3 0 0 3 3 3 0 gpW Prominin PF05478.11 KXT01004.1 - 1.6 6.6 9.5 0.38 8.6 4.7 2.0 2 0 0 2 2 2 0 Prominin GAS PF13851.6 KXT01004.1 - 1.6 8.1 24.3 0.7 9.2 1.7 3.8 3 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding Spc42p PF11544.8 KXT01004.1 - 2.6 8.1 7.3 0.35 10.9 1.9 2.4 2 0 0 2 2 2 0 Spindle pole body component Spc42p gpW PF02831.15 KXT01005.1 - 0.083 12.8 0.1 0.083 12.8 0.1 2.6 3 0 0 3 3 3 0 gpW Prominin PF05478.11 KXT01005.1 - 1.6 6.6 9.5 0.38 8.6 4.7 2.0 2 0 0 2 2 2 0 Prominin GAS PF13851.6 KXT01005.1 - 1.6 8.1 24.3 0.7 9.2 1.7 3.8 3 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding Spc42p PF11544.8 KXT01005.1 - 2.6 8.1 7.3 0.35 10.9 1.9 2.4 2 0 0 2 2 2 0 Spindle pole body component Spc42p MBOAT_2 PF13813.6 KXT01006.1 - 1.5e-16 60.4 10.0 4.7e-16 58.8 10.0 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family SYS1 PF09801.9 KXT01006.1 - 3.6 7.7 12.6 0.1 12.7 2.4 2.7 2 1 0 2 2 2 0 Integral membrane protein S linking to the trans Golgi network Transp_cyt_pur PF02133.15 KXT01007.1 - 3.5e-70 237.0 35.8 4.1e-70 236.8 35.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin CN_hydrolase PF00795.22 KXT01010.1 - 1e-43 149.6 0.0 1.8e-43 148.8 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Asp_Glu_race PF01177.22 KXT01010.1 - 6.5e-11 42.5 0.1 1.3e-10 41.5 0.1 1.6 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Amdase PF17645.1 KXT01010.1 - 3.1e-06 27.0 0.4 5.7e-06 26.1 0.4 1.4 1 0 0 1 1 1 1 Arylmalonate decarboxylase adh_short PF00106.25 KXT01011.1 - 6.6e-23 81.2 0.2 8.5e-23 80.8 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT01011.1 - 5e-17 62.2 0.2 6.2e-17 61.9 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT01011.1 - 5e-09 36.3 0.4 7.5e-09 35.7 0.4 1.3 1 1 0 1 1 1 1 KR domain DivIC PF04977.15 KXT01011.1 - 0.0044 16.8 0.0 0.0069 16.1 0.0 1.2 1 0 0 1 1 1 1 Septum formation initiator Shikimate_DH PF01488.20 KXT01011.1 - 0.0066 16.5 0.1 0.011 15.8 0.1 1.5 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DUF948 PF06103.11 KXT01011.1 - 0.027 14.7 0.2 0.042 14.1 0.2 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) B12-binding PF02310.19 KXT01011.1 - 0.086 12.9 0.1 0.19 11.7 0.1 1.5 1 1 0 1 1 1 0 B12 binding domain Polysacc_synt_2 PF02719.15 KXT01011.1 - 0.1 11.7 0.1 0.13 11.3 0.1 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.25 KXT01012.1 - 8e-32 110.3 0.4 1e-31 109.9 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT01012.1 - 2.6e-24 86.1 0.1 3.4e-24 85.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT01012.1 - 2.1e-11 44.1 0.3 6.1e-11 42.6 0.3 1.6 1 1 0 1 1 1 1 KR domain DivIC PF04977.15 KXT01012.1 - 0.0085 15.8 0.2 0.019 14.7 0.0 1.6 2 0 0 2 2 2 1 Septum formation initiator Shikimate_DH PF01488.20 KXT01012.1 - 0.013 15.6 0.2 0.036 14.1 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF1776 PF08643.10 KXT01012.1 - 0.027 13.8 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF948 PF06103.11 KXT01012.1 - 0.058 13.6 0.2 0.13 12.5 0.2 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) NAD_binding_1 PF00175.21 KXT01013.1 - 1.9e-23 83.2 0.0 3.5e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KXT01013.1 - 8e-19 67.8 0.0 1.3e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KXT01013.1 - 3e-08 33.9 0.0 4.7e-06 26.8 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 KXT01013.1 - 0.077 13.2 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain AA_permease_2 PF13520.6 KXT01014.1 - 8.4e-63 212.7 43.4 2.1e-61 208.0 43.4 2.0 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXT01014.1 - 1.2e-19 70.3 40.5 2.6e-19 69.2 40.4 1.5 1 1 0 1 1 1 1 Amino acid permease Trp_oprn_chp PF09534.10 KXT01015.1 - 0.03 14.1 4.1 0.036 13.9 4.1 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) GTP_EFTU PF00009.27 KXT01016.1 - 2.3e-65 219.8 0.2 4.8e-65 218.7 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KXT01016.1 - 5.2e-32 110.2 0.0 1.4e-31 108.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 KXT01016.1 - 1.1e-20 73.4 0.0 3.6e-20 71.8 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KXT01016.1 - 5.7e-12 45.9 0.0 1.7e-11 44.3 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KXT01016.1 - 1.3e-11 44.4 0.0 1.9e-10 40.7 0.0 2.8 3 0 0 3 3 3 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KXT01016.1 - 0.00025 21.1 0.3 0.00067 19.7 0.3 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase GST_N PF02798.20 KXT01017.1 - 3e-10 40.3 0.0 7.4e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXT01017.1 - 5.1e-09 36.4 0.0 1.1e-08 35.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXT01017.1 - 2.8e-06 27.5 0.0 5.9e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXT01017.1 - 0.011 15.7 0.0 0.031 14.3 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXT01017.1 - 0.012 15.8 0.0 0.028 14.6 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXT01017.1 - 0.031 14.5 0.0 0.19 11.9 0.0 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain JmjC PF02373.22 KXT01019.1 - 7e-39 132.8 0.6 1.5e-38 131.7 0.6 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.6 KXT01019.1 - 2.7e-20 72.6 4.4 4.9e-20 71.7 4.4 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KXT01019.1 - 1.2e-19 70.3 2.4 2.9e-19 69.1 2.4 1.7 1 0 0 1 1 1 1 PHD-like zinc-binding domain JmjN PF02375.17 KXT01019.1 - 2.2e-14 53.1 0.4 6.7e-14 51.6 0.4 1.9 1 0 0 1 1 1 1 jmjN domain HsbA PF12296.8 KXT01023.1 - 6.1e-14 52.5 0.2 1e-13 51.7 0.2 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Es2 PF09751.9 KXT01024.1 - 1.4e-120 404.0 8.4 2e-120 403.5 8.4 1.2 1 0 0 1 1 1 1 Nuclear protein Es2 NAAA-beta PF15508.6 KXT01025.1 - 0.00058 20.1 1.9 8.7 6.7 0.1 4.1 1 1 2 3 3 3 3 beta subunit of N-acylethanolamine-hydrolyzing acid amidase PdaC PF13739.6 KXT01025.1 - 0.0027 18.7 4.9 10 7.2 4.9 3.2 1 1 0 1 1 1 1 Deacetylase PdaC Sec5 PF15469.6 KXT01025.1 - 0.025 14.4 10.1 7.2e+02 -0.1 10.1 4.5 1 1 0 1 1 1 0 Exocyst complex component Sec5 CelTOS PF18659.1 KXT01025.1 - 0.028 14.9 4.6 6.8 7.1 0.5 3.0 1 1 2 3 3 3 0 Cell-traversal protein for ookinetes and sporozoites Epimerase PF01370.21 KXT01027.1 - 1e-22 80.8 0.2 8.7e-22 77.8 0.2 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXT01027.1 - 7.2e-12 45.4 0.2 1.9e-11 44.0 0.2 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KXT01027.1 - 2.2e-08 33.6 0.0 4.7e-08 32.5 0.0 1.5 2 0 0 2 2 2 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KXT01027.1 - 6e-08 32.0 0.0 2.4e-07 30.0 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KXT01027.1 - 5.8e-06 25.6 0.0 0.0003 20.0 0.1 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KXT01027.1 - 1.1e-05 24.8 0.0 2.2e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KXT01027.1 - 0.00021 21.3 0.0 0.00044 20.2 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Mito_carr PF00153.27 KXT01028.1 - 1.6e-16 60.0 2.5 5.2e-12 45.5 0.1 3.2 3 1 0 3 3 3 2 Mitochondrial carrier protein PHD PF00628.29 KXT01029.1 - 7.1e-08 32.2 6.8 7.1e-08 32.2 6.8 1.7 2 0 0 2 2 2 1 PHD-finger zf-PHD-like PF15446.6 KXT01029.1 - 0.027 14.1 3.2 0.069 12.8 3.2 1.7 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain zf-ribbon_3 PF13248.6 KXT01029.1 - 0.044 13.2 2.6 7.9 6.0 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain zf-HC5HC2H PF13771.6 KXT01029.1 - 0.095 13.0 4.1 0.24 11.7 4.1 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain TF_Zn_Ribbon PF08271.12 KXT01029.1 - 0.11 12.1 5.9 1.7 8.2 2.2 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding PHD_4 PF16866.5 KXT01029.1 - 1.5 9.0 8.1 0.24 11.5 3.9 1.9 2 0 0 2 2 2 0 PHD-finger YfhO PF09586.10 KXT01030.1 - 0.11 10.8 0.9 0.15 10.3 0.9 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Peptidase_C14 PF00656.22 KXT01030.1 - 0.12 12.4 0.2 0.2 11.6 0.2 1.3 1 0 0 1 1 1 0 Caspase domain FlxA PF14282.6 KXT01030.1 - 0.12 12.4 15.3 14 5.7 14.4 2.8 1 1 0 1 1 1 0 FlxA-like protein DUF1398 PF07166.11 KXT01030.1 - 0.13 12.4 0.4 0.24 11.5 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1398) Bul1_C PF04426.12 KXT01030.1 - 0.25 10.7 4.0 3.7 6.9 0.9 2.2 1 1 1 2 2 2 0 Bul1 C terminus AA_permease_2 PF13520.6 KXT01031.1 - 1.9e-59 201.6 54.5 2.2e-59 201.4 54.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXT01031.1 - 5.3e-30 104.4 48.9 7.2e-30 104.0 48.9 1.0 1 0 0 1 1 1 1 Amino acid permease Phage_holin_4_1 PF05105.12 KXT01031.1 - 0.46 10.6 7.9 0.065 13.4 2.2 2.6 2 1 0 2 2 2 0 Bacteriophage holin family DUF1275 PF06912.11 KXT01032.1 - 8.9e-09 35.5 0.1 1.1e-08 35.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) GPI2 PF06432.11 KXT01033.1 - 9.6e-127 422.2 1.1 1.1e-126 422.0 1.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Sporozoite_P67 PF05642.11 KXT01033.1 - 3.4 5.6 7.6 0.13 10.3 1.8 1.4 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Cupin_2 PF07883.11 KXT01035.1 - 0.15 11.8 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Cupin domain Fungal_trans PF04082.18 KXT01036.1 - 2.2e-23 82.6 0.2 5e-23 81.5 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT01036.1 - 4.2e-05 23.6 8.0 7.4e-05 22.8 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXT01037.1 - 2.1e-23 82.7 0.2 4.7e-23 81.6 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT01037.1 - 4e-05 23.7 8.0 7.1e-05 22.9 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAN_4 PF14295.6 KXT01038.1 - 4.9e-10 39.2 10.3 6.1e-05 22.8 0.2 3.8 3 0 0 3 3 3 3 PAN domain Esterase_phd PF10503.9 KXT01038.1 - 0.0018 17.8 0.0 0.0057 16.2 0.0 1.9 1 0 0 1 1 1 1 Esterase PHB depolymerase WD40 PF00400.32 KXT01039.1 - 1.1e-08 35.6 7.6 0.46 11.5 0.3 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXT01039.1 - 8e-05 22.9 0.0 0.69 10.3 0.0 3.7 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Myb_DNA-binding PF00249.31 KXT01039.1 - 0.12 12.6 0.0 0.31 11.3 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain BRE1 PF08647.11 KXT01040.1 - 0.37 10.9 38.5 6.4 6.9 22.9 3.6 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase Fucose_iso_N2 PF07882.12 KXT01040.1 - 1.7 8.2 10.0 2.5 7.6 1.0 2.3 1 1 1 2 2 2 0 L-fucose isomerase, second N-terminal domain KxDL PF10241.9 KXT01040.1 - 2.8 8.3 32.2 2.6 8.4 5.5 3.5 2 1 1 3 3 3 0 Uncharacterized conserved protein DUF572 PF04502.13 KXT01040.1 - 2.8 7.5 23.7 4.6 6.8 23.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) HrpB7 PF09486.10 KXT01040.1 - 4.6 7.6 31.7 2.4 8.6 6.5 3.7 1 1 3 4 4 4 0 Bacterial type III secretion protein (HrpB7) Exonuc_VII_L PF02601.15 KXT01040.1 - 5.8 6.4 33.1 1.8 8.1 18.9 2.2 1 1 1 2 2 2 0 Exonuclease VII, large subunit ATG16 PF08614.11 KXT01040.1 - 6.8 6.9 42.5 0.63 10.2 32.8 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) BRE1 PF08647.11 KXT01041.1 - 0.37 10.9 38.5 6.4 6.9 22.9 3.6 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase Fucose_iso_N2 PF07882.12 KXT01041.1 - 1.7 8.2 10.0 2.5 7.6 1.0 2.3 1 1 1 2 2 2 0 L-fucose isomerase, second N-terminal domain KxDL PF10241.9 KXT01041.1 - 2.8 8.3 32.2 2.6 8.4 5.5 3.5 2 1 1 3 3 3 0 Uncharacterized conserved protein DUF572 PF04502.13 KXT01041.1 - 2.8 7.5 23.7 4.6 6.8 23.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) HrpB7 PF09486.10 KXT01041.1 - 4.6 7.6 31.7 2.4 8.6 6.5 3.7 1 1 3 4 4 4 0 Bacterial type III secretion protein (HrpB7) Exonuc_VII_L PF02601.15 KXT01041.1 - 5.8 6.4 33.1 1.8 8.1 18.9 2.2 1 1 1 2 2 2 0 Exonuclease VII, large subunit ATG16 PF08614.11 KXT01041.1 - 6.8 6.9 42.5 0.63 10.2 32.8 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) zf-C2HC5 PF06221.13 KXT01043.1 - 0.2 11.7 4.1 0.36 10.9 4.1 1.5 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type DUF3510 PF12022.8 KXT01045.1 - 0.1 13.0 0.1 0.16 12.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) ATPgrasp_Ter PF15632.6 KXT01058.1 - 0.034 13.9 0.0 0.036 13.8 0.0 1.1 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon Rad21_Rec8_N PF04825.13 KXT01062.1 - 0.076 13.2 0.0 0.088 13.0 0.0 1.1 1 0 0 1 1 1 0 N terminus of Rad21 / Rec8 like protein Borrelia_P83 PF05262.11 KXT01067.1 - 0.88 8.0 8.8 1.3 7.4 8.8 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein RNA_pol_Rpc4 PF05132.14 KXT01067.1 - 1.3 9.4 6.4 1.9 8.9 6.4 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 CT47 PF15623.6 KXT01067.1 - 2.6 7.8 14.1 3.5 7.4 14.1 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 FGF-BP1 PF06473.12 KXT01067.1 - 3.7 7.3 8.7 5.3 6.8 8.7 1.2 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Acyl-CoA_ox_N PF14749.6 KXT01068.1 - 0.047 14.2 0.3 0.083 13.4 0.0 1.5 2 0 0 2 2 2 0 Acyl-coenzyme A oxidase N-terminal Planc_extracel PF07595.12 KXT01068.1 - 0.18 11.6 2.4 15 5.6 1.3 2.4 2 0 0 2 2 2 0 Planctomycete extracellular M-factor PF03855.13 KXT01071.1 - 0.52 10.5 3.9 1.6 8.9 3.9 1.9 1 0 0 1 1 1 0 M-factor Trypan_PARP PF05887.11 KXT01072.1 - 1.8 8.6 14.6 6.9 6.7 14.6 2.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Scm3 PF10384.9 KXT01076.1 - 9.2e-16 57.3 0.6 1.8e-15 56.4 0.6 1.5 1 0 0 1 1 1 1 Centromere protein Scm3 FNIP_N PF14636.6 KXT01077.1 - 0.27 12.2 3.5 0.51 11.3 3.5 1.4 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus RR_TM4-6 PF06459.12 KXT01077.1 - 0.55 10.0 10.8 0.74 9.6 10.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pannexin_like PF12534.8 KXT01077.1 - 5.7 5.9 6.6 8.3 5.4 6.6 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Presenilin PF01080.17 KXT01077.1 - 6.2 5.5 6.8 7.6 5.2 6.8 1.1 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 KXT01077.1 - 6.9 5.8 4.5 8.1 5.6 4.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter MBA1 PF07961.11 KXT01082.1 - 0.11 11.6 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 MBA1-like protein BKACE PF05853.12 KXT01083.1 - 0.045 13.1 0.1 0.076 12.3 0.1 1.4 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme LcnG-beta PF11632.8 KXT01084.1 - 0.19 11.7 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 Lactococcin G-beta NADH_dehy_S2_C PF06444.11 KXT01085.1 - 0.1 13.1 0.9 0.19 12.3 0.9 1.3 1 0 0 1 1 1 0 NADH dehydrogenase subunit 2 C-terminus TetR_C_37 PF18665.1 KXT01087.1 - 0.2 12.3 1.0 1.9 9.1 0.0 2.5 1 1 2 3 3 3 0 Tetracyclin repressor-like, C-terminal domain DivIC PF04977.15 KXT01088.1 - 0.0033 17.2 10.4 0.011 15.4 0.6 2.6 2 1 1 3 3 3 1 Septum formation initiator DUF790 PF05626.11 KXT01088.1 - 0.037 12.8 2.7 0.044 12.5 2.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF790) GAS PF13851.6 KXT01088.1 - 0.046 13.1 14.9 0.06 12.7 14.9 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding BLOC1_2 PF10046.9 KXT01088.1 - 0.05 13.9 6.5 0.34 11.3 0.2 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 bZIP_2 PF07716.15 KXT01088.1 - 0.063 13.4 3.0 0.063 13.4 3.0 3.0 2 1 1 3 3 3 0 Basic region leucine zipper FlaC_arch PF05377.11 KXT01088.1 - 0.11 12.9 5.8 3.8 8.0 0.4 3.1 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) KASH_CCD PF14662.6 KXT01088.1 - 0.13 12.1 15.6 0.28 11.0 15.6 1.5 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Ax_dynein_light PF10211.9 KXT01088.1 - 0.19 11.7 15.1 0.38 10.7 4.8 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain V_ATPase_I PF01496.19 KXT01088.1 - 0.19 9.6 9.2 0.44 8.4 3.1 1.8 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Macoilin PF09726.9 KXT01088.1 - 0.22 10.0 13.3 0.25 9.9 13.3 1.0 1 0 0 1 1 1 0 Macoilin family Prefoldin_2 PF01920.20 KXT01088.1 - 0.27 11.2 14.4 0.22 11.5 2.2 2.6 2 1 0 2 2 2 0 Prefoldin subunit Spc29 PF17082.5 KXT01088.1 - 0.29 11.0 8.6 1.4 8.7 2.6 2.1 1 1 1 2 2 2 0 Spindle Pole Component 29 Taxilin PF09728.9 KXT01088.1 - 0.34 10.1 17.3 0.098 11.8 2.4 2.1 1 1 1 2 2 2 0 Myosin-like coiled-coil protein Serine_rich PF08824.10 KXT01088.1 - 0.35 10.9 5.8 52 3.8 5.8 2.1 1 1 0 1 1 1 0 Serine rich protein interaction domain Tropomyosin_1 PF12718.7 KXT01088.1 - 0.52 10.5 15.1 9.9 6.3 15.1 2.3 1 1 0 1 1 1 0 Tropomyosin like DUF5339 PF17274.2 KXT01088.1 - 0.64 10.9 9.4 0.078 13.8 4.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5339) GIT1_C PF12205.8 KXT01088.1 - 0.95 9.6 7.2 2.6 8.2 1.2 2.2 1 1 1 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term HR1 PF02185.16 KXT01088.1 - 1.1 9.4 12.7 0.28 11.3 2.9 3.3 1 1 2 3 3 3 0 Hr1 repeat Swi5 PF07061.11 KXT01088.1 - 1.2 9.2 12.7 2.8 8.1 1.4 3.0 2 1 1 3 3 3 0 Swi5 TMF_DNA_bd PF12329.8 KXT01088.1 - 1.4 9.0 16.8 1.3 9.1 3.4 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4407 PF14362.6 KXT01088.1 - 1.7 7.9 5.6 2.1 7.6 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4140 PF13600.6 KXT01088.1 - 2.2 8.8 8.2 18 5.8 2.6 2.9 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) Sec2p PF06428.11 KXT01088.1 - 2.8 8.0 11.4 0.53 10.3 3.9 2.3 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p DUF3450 PF11932.8 KXT01088.1 - 2.8 7.2 10.1 9 5.5 4.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) TSC22 PF01166.18 KXT01088.1 - 2.9 8.3 8.1 0.22 11.8 2.0 2.2 2 1 0 2 2 2 0 TSC-22/dip/bun family Exonuc_VII_L PF02601.15 KXT01088.1 - 3.4 7.2 7.7 4.2 6.8 7.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit IFP_35_N PF07334.13 KXT01088.1 - 4.8 7.3 9.4 1.6 8.9 1.6 3.2 3 1 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Vir_act_alpha_C PF10400.9 KXT01088.1 - 5.9 7.6 9.2 40 5.0 0.2 2.8 1 1 1 2 2 2 0 Virulence activator alpha C-term Prefoldin PF02996.17 KXT01088.1 - 6 6.8 12.2 3.6 7.5 1.2 2.4 2 1 0 2 2 2 0 Prefoldin subunit APG6_N PF17675.1 KXT01088.1 - 6.4 7.3 19.6 8 7.0 3.3 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region UPF0449 PF15136.6 KXT01088.1 - 7 7.2 9.5 74 3.9 9.5 2.2 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 EMP24_GP25L PF01105.24 KXT01088.1 - 7 6.5 9.6 7.3 6.5 3.7 2.7 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Fmp27_WPPW PF10359.9 KXT01088.1 - 7.3 5.3 11.3 2.8 6.7 5.7 1.9 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF3552 PF12072.8 KXT01088.1 - 7.5 5.9 17.2 1.1 8.7 6.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) Rad21_Rec8 PF04824.16 KXT01090.1 - 0.08 12.2 0.1 0.15 11.3 0.1 1.4 1 0 0 1 1 1 0 Conserved region of Rad21 / Rec8 like protein DUF3950 PF13132.6 KXT01094.1 - 0.16 11.8 0.1 0.3 10.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3950) Proteasome PF00227.26 KXT01106.1 - 1.2e-47 161.8 0.5 3.7e-33 114.6 0.0 2.1 1 1 1 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 KXT01106.1 - 1.3e-11 43.9 0.7 1.8e-11 43.5 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature FXR_C3 PF16097.5 KXT01106.1 - 0.095 13.4 0.5 0.38 11.5 0.0 2.2 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 3 LSM PF01423.22 KXT01107.1 - 1.9e-17 62.7 0.0 2.6e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain Glyco_transf_20 PF00982.21 KXT01109.1 - 7.3e-161 536.0 0.1 1e-160 535.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KXT01109.1 - 7.9e-39 133.2 1.3 1.6e-38 132.2 0.0 2.0 2 0 0 2 2 2 1 Trehalose-phosphatase Cyclin PF08613.11 KXT01110.1 - 6.6e-38 130.6 11.6 4.5e-24 85.6 0.1 3.8 4 0 0 4 4 4 2 Cyclin FAD_binding_4 PF01565.23 KXT01111.1 - 1.1e-23 83.5 0.9 2e-23 82.7 0.9 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXT01111.1 - 1.4e-12 47.5 0.3 3e-12 46.4 0.3 1.6 1 0 0 1 1 1 1 Berberine and berberine like Ribosomal_L5_C PF00673.21 KXT01112.1 - 3.9e-22 78.2 0.0 5.9e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KXT01112.1 - 3.2e-20 72.2 0.0 8.9e-20 70.8 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L5 AMP-binding PF00501.28 KXT01113.1 - 0 1376.6 0.0 5.9e-72 242.6 0.0 6.6 6 0 0 6 6 6 6 AMP-binding enzyme Condensation PF00668.20 KXT01113.1 - 0 1039.9 0.0 6.6e-42 143.7 0.0 10.8 10 1 0 10 10 10 10 Condensation domain PP-binding PF00550.25 KXT01113.1 - 1.3e-82 272.1 9.0 1.1e-11 44.9 0.1 8.5 8 0 0 8 8 8 7 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KXT01113.1 - 4e-21 75.8 0.0 0.017 16.1 0.0 7.4 7 0 0 7 7 7 5 AMP-binding enzyme C-terminal domain Alpha-amylase PF00128.24 KXT01114.1 - 2e-58 198.6 0.0 2.9e-58 198.0 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 KXT01114.1 - 6.2e-25 87.3 0.1 1.3e-24 86.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) HMGL-like PF00682.19 KXT01115.1 - 1.2e-56 192.2 0.0 1.6e-56 191.8 0.0 1.1 1 0 0 1 1 1 1 HMGL-like p450 PF00067.22 KXT01116.1 - 9.2e-23 80.7 0.0 1.3e-22 80.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Proteasome PF00227.26 KXT01117.1 - 4.2e-47 160.1 0.5 4.9e-47 159.9 0.5 1.0 1 0 0 1 1 1 1 Proteasome subunit Hydrolase_4 PF12146.8 KXT01119.1 - 4.4e-15 55.6 0.0 1.1e-09 37.9 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXT01119.1 - 1.6e-08 34.6 0.0 6.9e-05 22.6 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXT01119.1 - 1.3e-05 25.9 0.0 6.2e-05 23.7 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family AXE1 PF05448.12 KXT01119.1 - 2.2e-05 23.3 0.1 0.58 8.8 0.0 3.0 2 1 1 3 3 3 3 Acetyl xylan esterase (AXE1) FSH1 PF03959.13 KXT01119.1 - 2.9e-05 23.8 0.0 4.7e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DUF818 PF05677.12 KXT01119.1 - 0.0012 17.8 0.0 0.0017 17.4 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) BAAT_C PF08840.11 KXT01119.1 - 0.0042 17.0 0.0 0.26 11.2 0.0 2.2 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 KXT01119.1 - 0.015 15.1 0.0 0.25 11.1 0.0 2.3 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KXT01119.1 - 0.018 14.6 0.0 0.07 12.6 0.0 1.8 1 1 0 1 1 1 0 Prolyl oligopeptidase family LIDHydrolase PF10230.9 KXT01119.1 - 0.023 14.2 0.0 6.2 6.3 0.0 2.1 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Abhydrolase_3 PF07859.13 KXT01119.1 - 0.045 13.6 0.0 0.085 12.7 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KXT01119.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Frag1 PF10277.9 KXT01120.1 - 1.3e-41 142.5 16.0 1.5e-41 142.3 16.0 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family AAA PF00004.29 KXT01121.1 - 1.3e-54 184.2 0.0 1.8e-42 144.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 KXT01121.1 - 7.5e-28 96.8 0.3 1.9e-27 95.5 0.3 1.8 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 KXT01121.1 - 2.9e-14 52.6 0.0 2.1e-08 33.9 0.0 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_2 PF07724.14 KXT01121.1 - 1.4e-08 35.1 0.0 0.007 16.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) NACHT PF05729.12 KXT01121.1 - 1.5e-08 34.8 0.3 1.3e-05 25.2 0.0 3.3 3 0 0 3 3 3 1 NACHT domain AAA_16 PF13191.6 KXT01121.1 - 1.7e-08 35.0 8.2 0.0053 17.1 0.1 5.0 3 2 2 5 5 5 2 AAA ATPase domain RuvB_N PF05496.12 KXT01121.1 - 1.1e-06 28.5 0.0 0.013 15.2 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KXT01121.1 - 4.1e-06 27.1 3.2 0.038 14.3 0.1 4.7 2 2 2 4 4 4 2 AAA domain AAA_7 PF12775.7 KXT01121.1 - 1e-05 25.1 0.0 0.00078 19.0 0.0 2.6 3 0 0 3 3 3 1 P-loop containing dynein motor region TsaE PF02367.17 KXT01121.1 - 1.1e-05 25.4 0.1 0.025 14.6 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 KXT01121.1 - 5.7e-05 23.1 0.1 0.33 10.9 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 KXT01121.1 - 6.9e-05 22.9 0.0 0.11 12.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KXT01121.1 - 0.0002 21.5 0.0 0.22 11.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KXT01121.1 - 0.00022 21.8 0.1 0.63 10.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KXT01121.1 - 0.00023 21.0 0.2 0.26 11.0 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_25 PF13481.6 KXT01121.1 - 0.00035 20.2 0.3 1.3 8.6 0.0 3.4 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 KXT01121.1 - 0.00064 19.1 0.1 0.24 10.7 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin TIP49 PF06068.13 KXT01121.1 - 0.0007 18.9 0.0 1.2 8.3 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain Sigma54_activat PF00158.26 KXT01121.1 - 0.00081 19.1 0.0 0.055 13.2 0.0 2.6 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_28 PF13521.6 KXT01121.1 - 0.0017 18.7 0.0 0.6 10.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KXT01121.1 - 0.0039 17.6 0.0 4.8 7.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Mg_chelatase PF01078.21 KXT01121.1 - 0.0068 15.8 0.1 0.77 9.1 0.1 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.6 KXT01121.1 - 0.0075 16.4 0.0 0.34 11.0 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain ABC_tran PF00005.27 KXT01121.1 - 0.017 15.7 0.7 5.9 7.4 0.0 3.0 3 0 0 3 3 2 0 ABC transporter ATPase PF06745.13 KXT01121.1 - 0.02 14.3 0.1 4.1 6.7 0.0 2.3 2 0 0 2 2 2 0 KaiC AAA_17 PF13207.6 KXT01121.1 - 0.027 14.9 0.2 2.3 8.6 0.1 2.8 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 KXT01121.1 - 0.061 12.8 0.1 5.4 6.4 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.6 KXT01121.1 - 0.073 12.8 0.1 14 5.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 KXT01121.1 - 0.12 12.3 0.2 0.59 10.0 0.0 2.2 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF815 PF05673.13 KXT01121.1 - 0.13 11.4 0.0 1.9 7.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) KAP_NTPase PF07693.14 KXT01121.1 - 0.15 11.3 0.4 0.82 8.8 0.0 2.1 1 1 1 2 2 2 0 KAP family P-loop domain NB-ARC PF00931.22 KXT01121.1 - 0.15 11.2 0.3 12 5.0 0.0 2.9 3 1 0 3 3 3 0 NB-ARC domain AAA_3 PF07726.11 KXT01121.1 - 0.15 11.9 0.0 8.9 6.2 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KXT01121.1 - 0.16 12.3 0.8 2.3 8.6 0.0 2.7 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 KXT01121.1 - 0.19 11.6 0.1 2.5 8.0 0.0 2.2 2 0 0 2 2 2 0 NTPase T2SSE PF00437.20 KXT01121.1 - 0.34 9.9 1.6 0.41 9.7 0.1 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein cobW PF02492.19 KXT01121.1 - 0.56 9.8 1.9 3 7.4 0.1 2.5 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain Lipase_3 PF01764.25 KXT01122.1 - 1.6e-30 105.8 0.0 2.3e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KXT01122.1 - 0.0029 18.3 0.0 0.0043 17.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXT01122.1 - 0.017 14.4 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Esterase PF00756.20 KXT01122.1 - 0.023 14.3 0.0 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 Putative esterase DUF3463 PF11946.8 KXT01122.1 - 0.042 13.7 0.0 0.09 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3463) DUF2974 PF11187.8 KXT01122.1 - 0.13 11.8 0.0 1.6 8.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) PGAP1 PF07819.13 KXT01122.1 - 0.13 11.9 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein ABC_membrane PF00664.23 KXT01123.1 - 7.4e-56 189.8 42.1 5.3e-37 128.0 21.0 3.2 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 KXT01123.1 - 3e-48 163.8 0.1 1.9e-27 96.4 0.0 3.1 3 0 0 3 3 2 2 ABC transporter Zeta_toxin PF06414.12 KXT01123.1 - 8.2e-08 31.8 0.0 1.6e-05 24.3 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin MMR_HSR1 PF01926.23 KXT01123.1 - 2e-05 24.7 2.6 0.14 12.2 0.2 3.2 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KXT01123.1 - 4.5e-05 23.1 1.9 0.2 11.4 0.1 3.0 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KXT01123.1 - 5.3e-05 23.7 0.1 0.079 13.3 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 KXT01123.1 - 0.0001 21.9 0.1 1.4 8.3 0.0 3.3 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KXT01123.1 - 0.00034 20.5 1.4 0.22 11.4 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 KXT01123.1 - 0.0012 18.6 1.1 1 9.0 0.1 2.6 2 0 0 2 2 2 2 AAA domain MeaB PF03308.16 KXT01123.1 - 0.0065 15.5 1.8 0.62 9.0 0.3 2.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF87 PF01935.17 KXT01123.1 - 0.0095 16.1 10.5 0.016 15.4 0.6 3.2 2 1 1 3 3 3 1 Helicase HerA, central domain AAA_25 PF13481.6 KXT01123.1 - 0.02 14.5 0.0 4.7 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 KXT01123.1 - 0.031 14.2 0.1 12 5.7 0.1 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_21 PF13304.6 KXT01123.1 - 0.038 13.8 7.2 0.65 9.7 0.1 3.5 3 1 1 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system Roc PF08477.13 KXT01123.1 - 0.042 14.1 0.2 1.5 9.0 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 KXT01123.1 - 0.05 13.9 1.4 12 6.2 0.0 3.0 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KXT01123.1 - 0.069 12.7 0.5 3.8 7.0 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 KXT01123.1 - 0.074 12.8 0.0 2.4 7.9 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein KAP_NTPase PF07693.14 KXT01123.1 - 0.079 12.2 0.2 0.38 9.9 0.0 2.3 2 1 0 2 2 2 0 KAP family P-loop domain Orf78 PF06024.12 KXT01123.1 - 0.095 13.0 5.3 0.4 11.0 2.6 3.1 3 0 0 3 3 3 0 Orf78 (ac78) NACHT PF05729.12 KXT01123.1 - 0.16 11.8 0.3 1.7 8.5 0.0 2.2 2 0 0 2 2 2 0 NACHT domain ATP_bind_1 PF03029.17 KXT01123.1 - 0.3 10.8 2.2 13 5.5 0.1 2.8 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 KXT01123.1 - 0.31 11.1 10.2 0.081 13.0 0.6 3.2 3 0 0 3 3 3 0 Dynamin family AAA_23 PF13476.6 KXT01123.1 - 0.63 10.5 13.3 5.9 7.3 0.0 4.3 3 1 1 4 4 3 0 AAA domain AAA PF00004.29 KXT01125.1 - 5.3e-17 62.5 0.0 1.2e-16 61.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KXT01125.1 - 0.00068 19.4 0.0 0.55 9.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KXT01125.1 - 0.013 15.8 0.0 0.029 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KXT01125.1 - 0.038 14.4 0.0 0.087 13.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 KXT01125.1 - 0.067 13.6 0.0 0.25 11.7 0.0 1.9 1 1 1 2 2 2 0 AAA ATPase domain AAA_11 PF13086.6 KXT01125.1 - 0.092 12.5 0.1 0.24 11.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain C2 PF00168.30 KXT01127.1 - 9e-14 51.6 0.1 1.6e-13 50.8 0.1 1.4 1 0 0 1 1 1 1 C2 domain AAA_17 PF13207.6 KXT01127.1 - 0.031 14.7 0.2 0.12 12.8 0.0 2.1 3 0 0 3 3 3 0 AAA domain BTB PF00651.31 KXT01129.1 - 1e-11 45.0 0.0 2.1e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain DnaJ PF00226.31 KXT01130.1 - 4.6e-10 39.5 0.5 1.1e-09 38.3 0.5 1.7 1 0 0 1 1 1 1 DnaJ domain DTHCT PF08070.11 KXT01130.1 - 0.015 16.0 5.0 0.015 16.0 5.0 1.7 2 0 0 2 2 2 0 DTHCT (NUC029) region NA37 PF04245.13 KXT01130.1 - 0.54 9.7 6.0 1.5 8.3 6.0 1.7 1 1 0 1 1 1 0 37-kD nucleoid-associated bacterial protein Ribonuclease_3 PF00636.26 KXT01131.1 - 1.7e-09 38.3 0.0 3e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KXT01131.1 - 3.9e-09 36.8 0.0 6.6e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like DUF4510 PF14971.6 KXT01131.1 - 0.1 13.0 1.0 0.16 12.3 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) F-box-like PF12937.7 KXT01132.1 - 0.034 14.0 0.2 0.069 13.1 0.2 1.5 1 0 0 1 1 1 0 F-box-like MGC-24 PF05283.11 KXT01132.1 - 0.042 14.3 0.7 0.073 13.5 0.7 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Pneumo_att_G PF05539.11 KXT01132.1 - 4 6.9 9.8 5.7 6.4 9.8 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G AMP-binding PF00501.28 KXT01135.1 - 8.4e-75 251.9 0.0 1e-74 251.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXT01135.1 - 2.1e-06 28.6 0.1 4.8e-06 27.5 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Aminotran_3 PF00202.21 KXT01137.1 - 1.6e-121 405.8 0.0 1.9e-121 405.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KXT01137.1 - 0.00089 18.5 0.0 0.0015 17.8 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KXT01137.1 - 0.012 14.9 0.0 0.036 13.3 0.0 1.8 1 1 0 1 1 1 0 Beta-eliminating lyase OAM_dimer PF16554.5 KXT01137.1 - 0.1 13.1 0.0 0.24 11.9 0.0 1.6 1 0 0 1 1 1 0 Dimerisation domain of d-ornithine 4,5-aminomutase 2-Hacid_dh_C PF02826.19 KXT01138.1 - 8.3e-36 123.0 0.0 1.1e-35 122.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXT01138.1 - 2.2e-11 43.5 0.0 2.3e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 KXT01138.1 - 0.027 14.5 0.0 0.049 13.7 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.6 KXT01138.1 - 0.042 14.4 0.0 0.093 13.2 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain F420_oxidored PF03807.17 KXT01138.1 - 0.058 14.0 0.1 0.14 12.7 0.1 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 KXT01139.1 - 8e-46 155.9 0.1 1.6e-45 154.9 0.0 1.5 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 KXT01139.1 - 2.9e-43 147.6 0.1 5.3e-43 146.7 0.1 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus DUF3543 PF12063.8 KXT01140.1 - 8.8e-85 284.1 0.1 1.5e-84 283.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 KXT01140.1 - 5.5e-63 212.8 0.0 9.7e-63 212.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT01140.1 - 2.2e-41 141.8 0.0 4.2e-41 141.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXT01140.1 - 0.01 14.6 1.0 0.044 12.6 0.0 2.4 3 0 0 3 3 3 0 Fungal protein kinase APH PF01636.23 KXT01140.1 - 0.045 13.7 0.6 0.13 12.2 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KXT01140.1 - 0.067 12.5 0.0 0.37 10.1 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Thioredoxin_7 PF13899.6 KXT01141.1 - 1.5e-15 57.1 0.0 3.6e-15 55.9 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.6 KXT01141.1 - 4.2e-13 48.9 0.4 1.1e-12 47.5 0.4 1.7 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 KXT01141.1 - 4.5e-07 30.0 0.0 8.2e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 UBX domain DUF4670 PF15709.5 KXT01141.1 - 0.00071 19.0 1.0 0.0021 17.5 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4670) Pyrophosphatase PF00719.19 KXT01141.1 - 0.0091 15.8 0.2 0.028 14.2 0.1 1.7 1 1 1 2 2 2 1 Inorganic pyrophosphatase Thioredoxin_2 PF13098.6 KXT01141.1 - 0.032 14.7 0.0 0.069 13.6 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like domain Thioredox_DsbH PF03190.15 KXT01141.1 - 0.077 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF255 ATP_sub_h PF10775.9 KXT01141.1 - 0.26 11.3 1.3 0.74 9.9 0.0 2.3 2 0 0 2 2 2 0 ATP synthase complex subunit h Homeobox_KN PF05920.11 KXT01142.1 - 0.2 11.6 8.1 0.37 10.7 0.2 2.9 2 1 1 3 3 3 0 Homeobox KN domain CTU2 PF10288.9 KXT01143.1 - 6.6 7.0 7.4 0.94 9.7 2.9 1.9 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 p450 PF00067.22 KXT01144.1 - 1.8e-22 79.8 0.0 4e-21 75.3 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 ABC_membrane PF00664.23 KXT01145.1 - 1.3e-71 241.5 22.6 7.6e-37 127.4 5.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXT01145.1 - 7.7e-61 204.6 0.0 6.8e-33 114.1 0.0 2.9 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 KXT01145.1 - 3.3e-14 52.8 0.1 0.0032 17.0 0.0 4.9 4 1 1 5 5 5 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KXT01145.1 - 1.2e-09 38.6 0.1 0.0033 17.7 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KXT01145.1 - 9.1e-08 32.7 1.5 0.002 18.5 0.0 3.5 2 1 1 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 KXT01145.1 - 2.9e-07 30.1 0.1 0.11 12.3 0.0 3.4 3 0 0 3 3 3 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KXT01145.1 - 4.5e-07 29.9 0.0 0.039 13.8 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 KXT01145.1 - 1.2e-06 28.6 0.5 0.35 10.6 0.0 4.2 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KXT01145.1 - 1.4e-06 28.1 0.1 0.063 12.9 0.0 3.6 4 0 0 4 4 4 2 AAA domain Rad17 PF03215.15 KXT01145.1 - 8e-06 25.9 0.0 0.17 11.8 0.0 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_18 PF13238.6 KXT01145.1 - 8.1e-06 26.4 0.4 0.36 11.4 0.4 3.4 2 1 1 3 3 3 2 AAA domain AAA_15 PF13175.6 KXT01145.1 - 1.8e-05 24.6 0.0 0.21 11.2 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_28 PF13521.6 KXT01145.1 - 5.2e-05 23.5 0.8 0.16 12.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KXT01145.1 - 0.0002 21.1 0.1 0.38 10.5 0.0 4.0 4 0 0 4 4 4 1 AAA domain AAA_23 PF13476.6 KXT01145.1 - 0.00022 21.8 0.0 0.097 13.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 KXT01145.1 - 0.00045 20.4 0.1 0.091 13.0 0.1 3.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit PRK PF00485.18 KXT01145.1 - 0.00094 19.0 0.4 0.55 9.9 0.1 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 KXT01145.1 - 0.0018 17.6 1.2 6.5 6.0 0.0 3.9 5 0 0 5 5 4 0 Zeta toxin AAA_5 PF07728.14 KXT01145.1 - 0.0022 18.0 0.0 2.4 8.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF87 PF01935.17 KXT01145.1 - 0.0024 18.0 0.3 1.2 9.2 0.1 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain NACHT PF05729.12 KXT01145.1 - 0.003 17.5 0.1 4 7.3 0.0 3.5 3 0 0 3 3 3 1 NACHT domain G-alpha PF00503.20 KXT01145.1 - 0.0035 16.5 0.1 1.1 8.4 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit ABC_ATPase PF09818.9 KXT01145.1 - 0.0053 15.6 1.0 0.033 13.0 0.0 2.6 4 0 0 4 4 4 1 Predicted ATPase of the ABC class AAA_7 PF12775.7 KXT01145.1 - 0.0053 16.3 0.0 1 8.9 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region tRNA_lig_kinase PF08303.11 KXT01145.1 - 0.0072 16.4 0.1 2.9 8.0 0.0 2.4 2 0 0 2 2 2 1 tRNA ligase kinase domain AAA PF00004.29 KXT01145.1 - 0.0078 16.6 0.3 2.8 8.4 0.2 3.7 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KXT01145.1 - 0.0098 15.6 0.0 1 9.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.25 KXT01145.1 - 0.012 15.3 0.1 0.17 11.6 0.0 2.5 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain IstB_IS21 PF01695.17 KXT01145.1 - 0.013 15.2 0.3 0.89 9.3 0.0 3.4 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_14 PF13173.6 KXT01145.1 - 0.015 15.3 0.0 2.3 8.2 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_33 PF13671.6 KXT01145.1 - 0.017 15.3 0.1 11 6.1 0.1 3.1 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KXT01145.1 - 0.019 14.3 0.0 0.2 11.0 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KXT01145.1 - 0.019 15.3 0.1 6.7 7.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase SRP54 PF00448.22 KXT01145.1 - 0.027 14.1 0.0 7.5 6.1 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NB-ARC PF00931.22 KXT01145.1 - 0.036 13.3 0.0 1.9 7.6 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_17 PF13207.6 KXT01145.1 - 0.041 14.3 0.9 6.3 7.2 0.0 3.0 3 0 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KXT01145.1 - 0.097 12.0 0.7 2.1 7.6 0.0 3.1 4 0 0 4 4 4 0 FtsK/SpoIIIE family ATPase PF06745.13 KXT01145.1 - 0.1 11.9 0.3 12 5.2 0.0 2.7 2 0 0 2 2 2 0 KaiC AAA_19 PF13245.6 KXT01145.1 - 0.12 12.8 0.0 13 6.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 KXT01145.1 - 0.17 11.6 0.0 39 3.9 0.0 3.4 3 0 0 3 3 3 0 DEAD/DEAH box helicase VirE PF05272.11 KXT01145.1 - 0.19 11.5 0.0 0.96 9.1 0.0 2.0 2 0 0 2 2 2 0 Virulence-associated protein E Proton_antipo_N PF00662.20 KXT01145.1 - 3.8 7.7 5.6 1.3 9.2 1.5 2.3 2 0 0 2 2 1 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Tyrosinase PF00264.20 KXT01151.1 - 1.2e-34 120.6 4.4 2.4e-34 119.5 4.4 1.5 1 0 0 1 1 1 1 Common central domain of tyrosinase Thioredoxin_4 PF13462.6 KXT01151.1 - 2.7e-08 34.1 0.0 8.3e-08 32.6 0.0 1.8 2 1 0 2 2 2 1 Thioredoxin DSBA PF01323.20 KXT01151.1 - 0.037 13.8 1.2 0.14 12.0 0.6 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain MFS_1 PF07690.16 KXT01152.1 - 3.3e-29 101.9 33.3 3.3e-29 101.9 33.3 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KXT01153.1 - 3.3e-29 101.9 33.3 3.3e-29 101.9 33.3 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 KXT01155.1 - 4.7e-71 239.2 0.0 6e-71 238.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT01155.1 - 9.4e-34 116.9 0.0 1.3e-33 116.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KXT01155.1 - 8.9e-12 45.5 0.3 2.8e-11 43.9 0.3 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 KXT01155.1 - 3.2e-06 26.4 0.0 4.6e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain C2 PF00168.30 KXT01155.1 - 0.0013 19.0 0.0 0.0026 18.0 0.0 1.4 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.6 KXT01155.1 - 0.0096 15.3 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 KXT01155.1 - 0.036 13.7 0.1 1.6 8.3 0.1 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KXT01155.1 - 0.18 11.7 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Amidohydro_2 PF04909.14 KXT01156.1 - 3.8e-30 105.7 0.0 8.8e-30 104.5 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase Fungal_trans PF04082.18 KXT01157.1 - 3.4e-30 105.0 0.0 6.8e-30 104.0 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT01157.1 - 1.1e-07 31.9 8.4 1.8e-07 31.2 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease_2 PF13520.6 KXT01159.1 - 2.8e-41 141.8 21.4 2.8e-41 141.8 21.4 1.5 1 1 1 2 2 2 1 Amino acid permease DUF3981 PF13139.6 KXT01159.1 - 0.14 12.6 1.9 0.16 12.4 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3981) SET PF00856.28 KXT01160.1 - 2.5e-11 44.2 0.1 7e-11 42.8 0.1 1.7 1 1 0 1 1 1 1 SET domain Amidohydro_1 PF01979.20 KXT01161.1 - 2e-26 93.1 1.5 7.5e-26 91.3 1.5 1.8 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXT01161.1 - 6.3e-15 55.6 3.4 8.7e-11 41.9 0.3 2.8 1 1 1 2 2 2 2 Amidohydrolase family Neuropep_like PF15161.6 KXT01161.1 - 0.015 14.9 0.1 0.058 13.1 0.1 2.0 1 0 0 1 1 1 0 Neuropeptide-like PEP_hydrolase PF09370.10 KXT01161.1 - 0.044 13.0 0.0 0.92 8.7 0.0 2.2 2 0 0 2 2 2 0 Phosphoenolpyruvate hydrolase-like Ank_2 PF12796.7 KXT01163.1 - 3.7e-29 101.1 1.2 8.2e-11 42.3 0.0 4.3 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.30 KXT01163.1 - 1.4e-18 66.4 6.3 8.7e-06 26.0 0.6 5.8 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 KXT01163.1 - 2.1e-18 66.4 5.6 3.5e-05 24.3 0.2 5.0 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXT01163.1 - 3.1e-18 64.0 5.5 3.3e-06 27.0 0.2 6.2 6 0 0 6 6 6 3 Ankyrin repeat DHHC PF01529.20 KXT01163.1 - 4.4e-15 56.0 5.2 4.4e-15 56.0 5.2 2.4 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank_5 PF13857.6 KXT01163.1 - 1.4e-14 54.0 1.7 2.8e-05 24.3 0.0 4.8 4 1 1 5 5 5 4 Ankyrin repeats (many copies) PDR_CDR PF06422.12 KXT01163.1 - 9.8 6.2 6.7 0.84 9.6 1.0 2.1 2 0 0 2 2 2 0 CDR ABC transporter NAD_binding_4 PF07993.12 KXT01164.1 - 6.6e-37 127.1 0.0 9.6e-37 126.5 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KXT01164.1 - 1.5e-28 99.6 0.0 2.4e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KXT01164.1 - 1.3e-13 51.0 0.0 2.6e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KXT01164.1 - 1.5e-06 28.4 0.3 9.5e-06 25.9 0.0 2.5 3 0 0 3 3 3 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 KXT01164.1 - 3.3e-05 23.0 0.0 0.00012 21.2 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KXT01164.1 - 6.6e-05 22.5 0.0 0.00017 21.1 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 KXT01164.1 - 0.00019 21.4 0.2 0.00042 20.3 0.2 1.6 1 1 0 1 1 1 1 KR domain DUF726 PF05277.12 KXT01165.1 - 1e-119 399.5 3.7 1.5e-119 399.0 3.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Arylsulfotran_2 PF14269.6 KXT01166.1 - 1.6e-44 152.5 0.0 1.1e-43 149.7 0.0 1.9 2 0 0 2 2 2 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KXT01166.1 - 2.2e-05 23.6 0.3 0.00018 20.5 0.3 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Fungal_trans_2 PF11951.8 KXT01167.1 - 9.4e-19 67.5 0.0 5.1e-12 45.3 2.9 3.1 2 1 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT01167.1 - 6.9e-08 32.5 11.0 1.2e-07 31.8 11.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXT01167.1 - 0.14 11.1 1.5 0.27 10.3 1.5 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain LRRNT_2 PF08263.12 KXT01168.1 - 0.0077 16.5 3.9 0.011 16.0 0.1 2.5 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain Pkinase PF00069.25 KXT01169.1 - 5.8e-18 65.2 0.0 1.1e-16 61.1 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain SMC_Nse1 PF07574.13 KXT01170.1 - 0.032 14.1 1.5 0.048 13.5 1.5 1.3 1 0 0 1 1 1 0 Nse1 non-SMC component of SMC5-6 complex SMC_Nse1 PF07574.13 KXT01171.1 - 0.049 13.5 1.6 0.084 12.8 1.6 1.3 1 0 0 1 1 1 0 Nse1 non-SMC component of SMC5-6 complex PSK PF06404.12 KXT01173.1 - 0.00082 20.3 14.2 0.18 12.9 0.0 4.1 3 1 1 4 4 4 3 Phytosulfokine precursor protein (PSK) zf-C2H2 PF00096.26 KXT01174.1 - 2.1e-10 40.5 21.2 0.0014 19.0 4.9 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXT01174.1 - 5.3e-06 26.8 18.5 0.035 14.9 2.3 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXT01174.1 - 9.2e-05 22.6 15.0 0.0011 19.1 8.4 3.2 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 KXT01174.1 - 0.0006 20.1 0.8 0.0027 18.0 0.2 2.0 2 0 0 2 2 2 1 C2H2-type zinc ribbon zf-met PF12874.7 KXT01174.1 - 0.0016 18.8 5.3 0.0016 18.8 5.3 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 KXT01174.1 - 0.0031 17.9 3.9 0.0031 17.9 3.9 5.0 5 0 0 5 5 5 1 Zinc-finger double domain FOXP-CC PF16159.5 KXT01174.1 - 0.38 11.4 6.3 7.6 7.2 0.0 3.1 2 1 0 2 2 2 0 FOXP coiled-coil domain zf-DBF PF07535.12 KXT01174.1 - 0.95 9.6 10.3 0.07 13.3 4.7 2.0 1 1 1 2 2 2 0 DBF zinc finger Abhydrolase_1 PF00561.20 KXT01176.1 - 1.6e-25 90.3 0.2 2.1e-21 76.7 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXT01176.1 - 1e-18 68.8 0.6 1.3e-18 68.4 0.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXT01176.1 - 2.3e-14 53.2 0.5 3e-13 49.6 0.5 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KXT01176.1 - 5.2e-06 25.4 0.0 0.0022 16.8 0.0 2.1 1 1 0 1 1 1 1 Ndr family Esterase PF00756.20 KXT01176.1 - 0.021 14.5 0.1 0.033 13.8 0.1 1.4 1 0 0 1 1 1 0 Putative esterase PhoPQ_related PF10142.9 KXT01176.1 - 0.041 12.6 0.0 0.1 11.2 0.0 1.6 2 0 0 2 2 2 0 PhoPQ-activated pathogenicity-related protein Peptidase_S9 PF00326.21 KXT01176.1 - 0.1 12.0 0.2 0.43 10.0 0.3 2.0 2 1 0 2 2 2 0 Prolyl oligopeptidase family LAMTOR5 PF16672.5 KXT01176.1 - 0.17 11.8 0.0 0.39 10.7 0.0 1.6 1 0 0 1 1 1 0 Ragulator complex protein LAMTOR5 WW PF00397.26 KXT01177.1 - 2.5e-05 24.3 0.2 5.8e-05 23.1 0.2 1.7 1 0 0 1 1 1 1 WW domain Zn_clus PF00172.18 KXT01177.1 - 0.00051 20.1 6.7 0.00092 19.3 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ntox8 PF15545.6 KXT01177.1 - 0.092 12.9 0.1 0.27 11.4 0.1 1.8 1 0 0 1 1 1 0 Bacterial toxin 8 Acetyltransf_1 PF00583.25 KXT01179.1 - 2e-13 50.6 0.0 3.5e-13 49.8 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXT01179.1 - 9.2e-12 45.0 0.0 1.4e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXT01179.1 - 1.3e-09 38.4 0.0 2e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXT01179.1 - 0.0001 22.4 0.0 0.00059 19.9 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXT01179.1 - 0.00027 20.8 0.0 0.0006 19.7 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KXT01179.1 - 0.0084 16.2 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase MOZ_SAS PF01853.18 KXT01179.1 - 0.22 11.2 0.0 0.37 10.4 0.0 1.3 1 0 0 1 1 1 0 MOZ/SAS family Acetyltransf_1 PF00583.25 KXT01180.1 - 1.4e-13 51.1 0.0 2.5e-13 50.3 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXT01180.1 - 7e-12 45.4 0.0 1e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXT01180.1 - 9.7e-10 38.7 0.0 1.5e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXT01180.1 - 7.2e-05 22.9 0.0 0.00046 20.3 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXT01180.1 - 0.00021 21.2 0.0 0.00047 20.1 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KXT01180.1 - 0.007 16.5 0.0 0.013 15.7 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase MOZ_SAS PF01853.18 KXT01180.1 - 0.18 11.5 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 MOZ/SAS family Acetyltransf_16 PF05301.11 KXT01180.1 - 0.2 11.4 0.0 0.33 10.7 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase, Mec-17 TGT PF01702.18 KXT01182.1 - 2.3e-135 451.3 0.0 2.7e-135 451.0 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase F-box-like_2 PF13013.6 KXT01183.1 - 0.0084 16.1 0.1 0.016 15.2 0.1 1.7 1 1 0 1 1 1 1 F-box-like domain Wx5_PLAF3D7 PF09688.10 KXT01183.1 - 0.044 13.8 0.1 0.051 13.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (Wx5_PLAF3D7) Pkinase PF00069.25 KXT01184.1 - 5.5e-13 48.9 0.0 9e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT01184.1 - 0.058 12.7 0.0 0.28 10.4 0.0 2.0 1 1 0 1 1 1 0 Protein tyrosine kinase Asp_protease PF09668.10 KXT01187.1 - 3.3e-60 201.3 0.1 5.3e-60 200.7 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KXT01187.1 - 9e-23 80.7 0.0 1.9e-22 79.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KXT01187.1 - 1.3e-11 44.9 0.0 3.4e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease UBA PF00627.31 KXT01187.1 - 6.5e-08 32.3 0.1 1.3e-07 31.4 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain ubiquitin PF00240.23 KXT01187.1 - 9.7e-07 28.5 0.0 2.1e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family RVP_2 PF08284.11 KXT01187.1 - 8.8e-05 22.3 0.0 0.00018 21.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 KXT01187.1 - 0.0013 19.0 1.5 0.034 14.5 0.0 3.3 3 1 1 4 4 4 1 Retroviral aspartyl protease UBA_4 PF14555.6 KXT01187.1 - 0.002 17.9 0.3 0.0043 16.8 0.3 1.6 1 0 0 1 1 1 1 UBA-like domain YukD PF08817.10 KXT01187.1 - 0.18 12.5 0.0 0.65 10.7 0.0 1.9 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD ZZ PF00569.17 KXT01188.1 - 5e-11 42.2 5.0 1e-10 41.2 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.31 KXT01188.1 - 9.4e-08 32.1 0.0 3e-07 30.5 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM PF04433.17 KXT01188.1 - 4.4e-06 26.9 0.1 1.7e-05 25.1 0.0 2.0 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-bind_6 PF13921.6 KXT01188.1 - 0.0028 17.9 0.0 0.0067 16.7 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain KN_motif PF12075.8 KXT01188.1 - 0.066 13.0 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 KN motif Tic110 PF16940.5 KXT01188.1 - 0.069 11.6 0.1 1.3 7.4 0.0 2.2 2 0 0 2 2 2 0 Chloroplast envelope transporter DUF4239 PF14023.6 KXT01188.1 - 0.14 11.8 0.5 0.24 11.1 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) ADH_zinc_N PF00107.26 KXT01189.1 - 6.8e-11 42.3 0.5 1.1e-10 41.6 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXT01189.1 - 1.5e-09 37.7 0.0 3.3e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 KXT01189.1 - 0.056 12.9 0.3 0.084 12.3 0.3 1.2 1 0 0 1 1 1 0 short chain dehydrogenase PGM_PMM_II PF02879.16 KXT01189.1 - 0.13 12.9 0.0 0.31 11.7 0.0 1.6 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II DUF2855 PF11017.8 KXT01189.1 - 0.16 11.7 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) Ctr PF04145.15 KXT01190.1 - 1.1e-41 142.9 0.1 1.6e-41 142.4 0.1 1.2 1 0 0 1 1 1 1 Ctr copper transporter family DUF2244 PF10003.9 KXT01190.1 - 0.69 9.6 2.3 2.1 8.0 2.3 1.7 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) Fe-ADH PF00465.19 KXT01191.1 - 1.6e-66 224.6 0.2 2.1e-66 224.2 0.2 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KXT01191.1 - 1.8e-11 44.2 0.0 3.1e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase WW PF00397.26 KXT01193.1 - 0.0002 21.3 0.0 0.00066 19.7 0.0 2.0 1 0 0 1 1 1 1 WW domain Fcf1 PF04900.12 KXT01194.1 - 8.1e-33 112.8 0.1 1.3e-32 112.1 0.1 1.4 1 0 0 1 1 1 1 Fcf1 OPA3 PF07047.12 KXT01195.1 - 5.7e-43 145.7 10.5 1.2e-42 144.6 10.5 1.7 1 1 0 1 1 1 1 Optic atrophy 3 protein (OPA3) RNA_pol_Rpc4 PF05132.14 KXT01195.1 - 1.3 9.5 10.1 0.32 11.4 0.9 2.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 RR_TM4-6 PF06459.12 KXT01195.1 - 3.1 7.5 16.9 0.13 12.1 5.5 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Ribonucleas_3_3 PF14622.6 KXT01218.1 - 8.1e-05 22.8 0.0 0.00012 22.2 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KXT01218.1 - 0.12 13.0 0.1 1.9 9.1 0.1 2.3 1 1 0 1 1 1 0 Ribonuclease III domain SprT-like PF10263.9 KXT01219.1 - 0.00013 21.8 0.2 0.00057 19.7 0.2 2.0 1 1 0 1 1 1 1 SprT-like family WLM PF08325.10 KXT01219.1 - 0.14 12.2 0.1 0.24 11.5 0.1 1.3 1 0 0 1 1 1 0 WLM domain JAB PF01398.21 KXT01225.1 - 8.9e-33 112.8 0.0 1.5e-32 112.0 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KXT01225.1 - 1.3e-12 48.1 0.2 2.7e-12 47.1 0.2 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 KXT01225.1 - 2.9e-07 30.3 0.0 5.5e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Phasin_2 PF09361.10 KXT01226.1 - 0.12 12.6 18.5 1.1 9.6 0.3 5.6 6 0 0 6 6 6 0 Phasin protein UPF0184 PF03670.13 KXT01226.1 - 0.56 10.6 5.7 1.7 9.1 0.1 3.7 3 1 1 4 4 4 0 Uncharacterised protein family (UPF0184) IZUMO PF15005.6 KXT01226.1 - 3.8 8.0 10.5 4.2 7.9 0.3 4.3 3 2 1 4 4 4 0 Izumo sperm-egg fusion, Ig domain-associated Baculo_PEP_C PF04513.12 KXT01226.1 - 4.9 7.2 10.0 0.4 10.7 0.2 3.3 3 1 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus ABC_membrane PF00664.23 KXT01227.1 - 3.7e-47 161.3 24.9 1.4e-28 100.4 12.7 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 KXT01227.1 - 9.9e-47 158.9 0.2 4.1e-29 101.8 0.1 2.7 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 KXT01227.1 - 3.3e-12 46.3 2.5 1.4e-05 24.6 0.1 4.3 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KXT01227.1 - 1.1e-05 25.8 0.1 0.18 12.1 0.3 3.1 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.6 KXT01227.1 - 7.2e-05 23.4 0.2 0.37 11.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KXT01227.1 - 8.8e-05 22.2 1.1 0.015 15.0 0.9 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KXT01227.1 - 9.1e-05 22.4 0.1 1.5 8.6 0.0 3.9 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 KXT01227.1 - 0.0029 17.7 0.1 0.82 9.8 0.0 3.4 3 0 0 3 3 3 1 50S ribosome-binding GTPase DUF87 PF01935.17 KXT01227.1 - 0.0043 17.2 0.4 0.0094 16.1 0.4 1.5 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_25 PF13481.6 KXT01227.1 - 0.0062 16.1 0.3 0.078 12.5 0.1 2.4 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KXT01227.1 - 0.0092 15.9 0.0 1.1 9.1 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KXT01227.1 - 0.021 15.2 3.4 4.9 7.5 0.0 3.3 4 0 0 4 4 2 0 AAA ATPase domain Dynamin_N PF00350.23 KXT01227.1 - 0.024 14.7 0.2 1.7 8.7 0.0 2.7 2 0 0 2 2 2 0 Dynamin family IstB_IS21 PF01695.17 KXT01227.1 - 0.032 14.0 1.9 3.3 7.4 0.0 3.6 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_15 PF13175.6 KXT01227.1 - 0.064 13.0 0.4 6.5 6.4 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 KXT01227.1 - 0.076 13.2 0.3 8.7 6.5 0.4 2.9 2 1 0 2 2 2 0 AAA domain T2SSE PF00437.20 KXT01227.1 - 0.077 12.1 0.1 10 5.1 0.3 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein SbcCD_C PF13558.6 KXT01227.1 - 0.082 13.2 0.0 8.1 6.8 0.0 2.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit FtsK_SpoIIIE PF01580.18 KXT01227.1 - 0.13 11.6 0.7 1.2 8.5 0.5 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Pox_A32 PF04665.12 KXT01227.1 - 0.21 11.0 1.3 0.58 9.6 0.1 2.1 2 0 0 2 2 2 0 Poxvirus A32 protein DUF3382 PF11862.8 KXT01227.1 - 2.2 8.6 11.4 3.6 7.9 0.3 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3382) ABC_ATPase PF09818.9 KXT01227.1 - 8.4 5.1 6.7 9.7 4.9 0.0 3.1 4 0 0 4 4 4 0 Predicted ATPase of the ABC class Ribonuclease_3 PF00636.26 KXT01228.1 - 0.025 15.2 0.0 0.068 13.8 0.0 1.8 1 1 0 1 1 1 0 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KXT01228.1 - 0.03 14.5 0.0 2.9 8.1 0.0 2.2 2 0 0 2 2 2 0 Ribonuclease-III-like DUF1967 PF09269.11 KXT01228.1 - 0.073 13.0 0.1 0.34 10.9 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1967) MscS_porin PF12795.7 KXT01235.1 - 0.0013 18.4 12.4 0.0018 17.9 12.4 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain YabA PF06156.13 KXT01235.1 - 0.33 11.6 1.6 0.75 10.5 1.0 1.8 1 1 1 2 2 2 0 Initiation control protein YabA DivIC PF04977.15 KXT01235.1 - 0.36 10.6 7.4 3 7.7 0.3 2.4 1 1 1 2 2 2 0 Septum formation initiator ZapB PF06005.12 KXT01235.1 - 3.5 8.1 8.9 1.3 9.5 1.1 2.5 1 1 1 2 2 2 0 Cell division protein ZapB MFS_1 PF07690.16 KXT01238.1 - 3.4e-13 49.3 16.3 3.4e-13 49.3 16.3 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Pam17 PF08566.10 KXT01238.1 - 0.15 11.9 0.6 0.5 10.2 0.0 2.2 3 0 0 3 3 3 0 Mitochondrial import protein Pam17 DUF3552 PF12072.8 KXT01238.1 - 1.9 7.8 6.0 8.3 5.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) DUF3018 PF11455.8 KXT01239.1 - 0.075 13.0 1.4 0.42 10.6 0.9 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3018) SNF2_N PF00176.23 KXT01240.1 - 1e-51 175.8 0.2 1.6e-51 175.1 0.2 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.6 KXT01240.1 - 4.5e-23 81.1 1.4 9.6e-23 80.1 1.4 1.6 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.31 KXT01240.1 - 1.6e-18 67.1 0.0 2.8e-17 63.0 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXT01240.1 - 1.3e-05 25.2 0.0 5.2e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KXT01240.1 - 0.00034 19.9 0.0 0.00069 18.9 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SEC-C PF02810.15 KXT01240.1 - 1.6 8.8 7.8 2.9 7.9 7.8 1.5 1 0 0 1 1 1 0 SEC-C motif 6PGD PF00393.19 KXT01241.1 - 4.4e-87 292.1 0.0 6.4e-87 291.6 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KXT01241.1 - 3.4e-30 105.3 0.0 6.2e-30 104.4 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KXT01241.1 - 3.5e-08 33.5 0.0 7.4e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KXT01241.1 - 0.00024 21.6 0.0 0.00081 19.9 0.0 2.0 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 KXT01241.1 - 0.0003 21.0 0.0 0.24 11.7 0.0 3.1 3 0 0 3 3 3 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_11 PF14833.6 KXT01241.1 - 0.0029 17.9 0.7 0.0053 17.0 0.1 1.7 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_Gly3P_dh_N PF01210.23 KXT01241.1 - 0.0083 16.1 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 KXT01241.1 - 0.0084 15.8 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 KXT01241.1 - 0.085 12.4 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.27 KXT01241.1 - 0.087 13.4 0.0 0.19 12.3 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ING PF12998.7 KXT01242.1 - 1.7e-19 70.3 0.1 2.6e-19 69.6 0.1 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KXT01242.1 - 9.3e-07 28.6 9.0 2.1e-06 27.5 9.0 1.6 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KXT01242.1 - 0.0055 16.9 0.2 0.014 15.7 0.2 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain PHD_2 PF13831.6 KXT01242.1 - 0.021 14.4 3.8 0.049 13.2 3.8 1.6 1 0 0 1 1 1 0 PHD-finger TFIIA PF03153.13 KXT01242.1 - 0.024 14.6 3.3 0.042 13.9 3.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SWIRM-assoc_2 PF16496.5 KXT01242.1 - 0.36 9.7 4.9 0.55 9.0 4.9 1.2 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Pex2_Pex12 PF04757.14 KXT01243.1 - 6.2e-33 114.3 4.4 1.1e-32 113.4 4.4 1.4 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region RDD PF06271.12 KXT01243.1 - 0.00044 20.5 0.8 0.011 16.0 0.2 2.2 1 1 1 2 2 2 2 RDD family zf-C3HC4_4 PF15227.6 KXT01243.1 - 0.0049 17.0 4.9 0.01 15.9 4.9 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING DUF5476 PF17570.2 KXT01243.1 - 0.11 12.9 0.5 0.31 11.5 0.5 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5476) NMN_transporter PF04973.12 KXT01243.1 - 0.19 11.7 2.8 1.6 8.7 0.1 2.4 2 1 1 3 3 3 0 Nicotinamide mononucleotide transporter Abhydrolase_6 PF12697.7 KXT01244.1 - 4.7e-11 43.7 0.5 7.4e-11 43.1 0.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXT01244.1 - 9.5e-07 28.3 0.0 1.5e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXT01244.1 - 9.4e-05 22.2 0.0 0.00027 20.7 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 KXT01244.1 - 0.01 14.8 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Esterase PF00756.20 KXT01244.1 - 0.01 15.5 0.4 0.017 14.8 0.0 1.6 2 0 0 2 2 2 0 Putative esterase Ndr PF03096.14 KXT01244.1 - 0.066 11.9 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 Ndr family PGAP1 PF07819.13 KXT01244.1 - 0.066 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Peptidase_S9 PF00326.21 KXT01244.1 - 0.069 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Fez1 PF06818.15 KXT01246.1 - 0.0025 18.3 1.8 0.0028 18.1 1.8 1.0 1 0 0 1 1 1 1 Fez1 RYDR_ITPR PF01365.21 KXT01246.1 - 0.015 14.7 0.3 0.02 14.3 0.3 1.2 1 0 0 1 1 1 0 RIH domain LPP PF04728.13 KXT01246.1 - 0.019 15.3 3.1 0.49 10.8 2.1 3.3 3 2 1 4 4 4 0 Lipoprotein leucine-zipper Ntox15 PF15604.6 KXT01246.1 - 0.023 14.8 3.1 0.031 14.4 2.2 1.6 1 1 1 2 2 2 0 Novel toxin 15 B2 PF11473.8 KXT01246.1 - 0.026 14.3 0.1 0.46 10.3 0.0 2.3 1 1 1 2 2 2 0 RNA binding protein B2 TetR_C_29 PF17938.1 KXT01246.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.5 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Fez1 PF06818.15 KXT01247.1 - 0.0025 18.3 1.8 0.0028 18.1 1.8 1.0 1 0 0 1 1 1 1 Fez1 RYDR_ITPR PF01365.21 KXT01247.1 - 0.015 14.7 0.3 0.02 14.3 0.3 1.2 1 0 0 1 1 1 0 RIH domain LPP PF04728.13 KXT01247.1 - 0.019 15.3 3.1 0.49 10.8 2.1 3.3 3 2 1 4 4 4 0 Lipoprotein leucine-zipper Ntox15 PF15604.6 KXT01247.1 - 0.023 14.8 3.1 0.031 14.4 2.2 1.6 1 1 1 2 2 2 0 Novel toxin 15 B2 PF11473.8 KXT01247.1 - 0.026 14.3 0.1 0.46 10.3 0.0 2.3 1 1 1 2 2 2 0 RNA binding protein B2 TetR_C_29 PF17938.1 KXT01247.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.5 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Fez1 PF06818.15 KXT01248.1 - 0.0025 18.3 1.8 0.0028 18.1 1.8 1.0 1 0 0 1 1 1 1 Fez1 RYDR_ITPR PF01365.21 KXT01248.1 - 0.015 14.7 0.3 0.02 14.3 0.3 1.2 1 0 0 1 1 1 0 RIH domain LPP PF04728.13 KXT01248.1 - 0.019 15.3 3.1 0.49 10.8 2.1 3.3 3 2 1 4 4 4 0 Lipoprotein leucine-zipper Ntox15 PF15604.6 KXT01248.1 - 0.023 14.8 3.1 0.031 14.4 2.2 1.6 1 1 1 2 2 2 0 Novel toxin 15 B2 PF11473.8 KXT01248.1 - 0.026 14.3 0.1 0.46 10.3 0.0 2.3 1 1 1 2 2 2 0 RNA binding protein B2 TetR_C_29 PF17938.1 KXT01248.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.5 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Fez1 PF06818.15 KXT01249.1 - 0.0025 18.3 1.8 0.0028 18.1 1.8 1.0 1 0 0 1 1 1 1 Fez1 RYDR_ITPR PF01365.21 KXT01249.1 - 0.015 14.7 0.3 0.02 14.3 0.3 1.2 1 0 0 1 1 1 0 RIH domain LPP PF04728.13 KXT01249.1 - 0.019 15.3 3.1 0.49 10.8 2.1 3.3 3 2 1 4 4 4 0 Lipoprotein leucine-zipper Ntox15 PF15604.6 KXT01249.1 - 0.023 14.8 3.1 0.031 14.4 2.2 1.6 1 1 1 2 2 2 0 Novel toxin 15 B2 PF11473.8 KXT01249.1 - 0.026 14.3 0.1 0.46 10.3 0.0 2.3 1 1 1 2 2 2 0 RNA binding protein B2 TetR_C_29 PF17938.1 KXT01249.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.5 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Hist_deacetyl PF00850.19 KXT01250.1 - 1.1e-80 271.5 0.1 2.4e-80 270.3 0.0 1.6 2 0 0 2 2 2 1 Histone deacetylase domain Pro-kuma_activ PF09286.11 KXT01251.1 - 7.4e-40 136.5 0.0 1.5e-39 135.5 0.0 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain NIF PF03031.18 KXT01254.1 - 5.8e-37 126.9 0.0 8.4e-37 126.3 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HTH_38 PF13936.6 KXT01254.1 - 0.0079 15.9 0.1 1.9 8.3 0.0 2.7 1 1 1 2 2 2 2 Helix-turn-helix domain HTH_7 PF02796.15 KXT01254.1 - 0.048 13.7 0.1 2.3 8.4 0.0 2.5 1 1 1 2 2 2 0 Helix-turn-helix domain of resolvase Pro_dh PF01619.18 KXT01255.1 - 5.1e-66 223.2 1.8 6.1e-66 223.0 1.8 1.0 1 0 0 1 1 1 1 Proline dehydrogenase bZIP_2 PF07716.15 KXT01255.1 - 0.1 12.7 3.4 0.26 11.4 3.4 1.7 1 0 0 1 1 1 0 Basic region leucine zipper Hist_deacetyl PF00850.19 KXT01256.1 - 7e-74 249.1 0.0 9e-74 248.7 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Pribosyltran PF00156.27 KXT01257.1 - 9.4e-14 51.2 0.0 1.4e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KXT01257.1 - 0.016 14.6 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 KXT01257.1 - 0.056 12.9 0.0 0.081 12.4 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase Abhydrolase_3 PF07859.13 KXT01258.1 - 1e-43 149.6 0.0 1.3e-43 149.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXT01258.1 - 1.7e-06 27.2 0.0 3.2e-06 26.3 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Thioesterase PF00975.20 KXT01258.1 - 0.019 15.0 0.0 0.033 14.3 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain AXE1 PF05448.12 KXT01258.1 - 0.12 11.0 0.0 0.38 9.4 0.0 1.7 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 KXT01258.1 - 0.13 11.7 0.1 0.33 10.4 0.1 1.6 1 1 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KXT01258.1 - 0.66 10.5 4.3 1.6 9.3 4.3 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Transp_cyt_pur PF02133.15 KXT01260.1 - 1.6e-20 73.3 37.7 5.6e-20 71.5 37.7 1.8 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF1616 PF07760.11 KXT01260.1 - 2.4 7.4 5.8 5.1 6.4 5.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) DUF4863 PF16155.5 KXT01262.1 - 1e-50 171.5 0.1 1.3e-48 164.8 0.1 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4863) Lactamase_B PF00753.27 KXT01262.1 - 1.5e-09 38.2 0.4 3.9e-09 36.8 0.4 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXT01262.1 - 2.6e-05 23.9 0.0 6.1e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF1737 PF08410.10 KXT01262.1 - 0.11 12.4 0.5 0.41 10.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1737) ArAE_1_C PF11728.8 KXT01262.1 - 0.11 12.5 0.1 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 Putative aromatic acid exporter C-terminal domain COMMD1_N PF17221.3 KXT01263.1 - 0.11 12.8 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 COMMD1 N-terminal domain TENA_THI-4 PF03070.16 KXT01263.1 - 0.13 12.1 2.2 0.15 11.8 0.5 2.0 2 1 0 2 2 2 0 TENA/THI-4/PQQC family Glyco_hydro_47 PF01532.20 KXT01264.1 - 2.9e-115 385.8 0.0 3.5e-115 385.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Zn_clus PF00172.18 KXT01266.1 - 1.8e-05 24.7 9.7 4.1e-05 23.6 9.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_49 PF03718.13 KXT01266.1 - 2.9 7.9 7.2 7.6 6.6 2.6 2.4 1 1 2 3 3 3 0 Glycosyl hydrolase family 49 Shugoshin_N PF07558.11 KXT01266.1 - 3.5 7.6 6.1 10 6.1 0.1 3.2 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region Toxin_22 PF08092.11 KXT01267.1 - 0.099 12.7 2.1 0.24 11.5 2.1 1.6 1 0 0 1 1 1 0 Magi peptide toxin family DUF3106 PF11304.8 KXT01270.1 - 0.07 13.6 1.3 0.3 11.6 0.2 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3106) zf-RING_2 PF13639.6 KXT01272.1 - 1.9e-05 24.9 7.1 3.8e-05 23.9 7.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KXT01272.1 - 0.00013 21.9 6.9 0.00021 21.2 6.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 KXT01272.1 - 0.0016 18.1 1.2 0.0016 18.1 1.2 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 KXT01272.1 - 0.13 12.1 4.9 0.23 11.3 4.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXT01272.1 - 0.45 10.4 6.5 0.84 9.6 6.5 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KXT01272.1 - 0.63 9.9 6.7 1.3 8.9 6.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF3328 PF11807.8 KXT01273.1 - 1.5e-35 123.0 2.1 1.8e-35 122.7 2.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) PP-binding PF00550.25 KXT01274.1 - 5.6e-08 33.0 0.6 2.8e-06 27.6 0.1 2.4 2 0 0 2 2 2 1 Phosphopantetheine attachment site Condensation PF00668.20 KXT01274.1 - 0.00075 18.3 0.1 0.00098 17.9 0.1 1.1 1 0 0 1 1 1 1 Condensation domain Terminase_4 PF05119.12 KXT01275.1 - 1.2 9.6 5.5 0.48 10.9 2.1 2.2 2 1 1 3 3 3 0 Phage terminase, small subunit Histone_HNS PF00816.21 KXT01275.1 - 2.3 9.1 10.7 35 5.3 8.8 2.7 2 0 0 2 2 2 0 H-NS histone family RR_TM4-6 PF06459.12 KXT01275.1 - 4.7 6.9 13.8 2.2 8.0 11.7 1.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Phage_integrase PF00589.22 KXT01276.1 - 0.14 11.9 2.2 0.32 10.8 1.7 1.7 1 1 0 1 1 1 0 Phage integrase family Phage_integrase PF00589.22 KXT01277.1 - 0.18 11.6 2.1 0.4 10.5 1.8 1.7 1 1 0 1 1 1 0 Phage integrase family DUF3328 PF11807.8 KXT01278.1 - 3.1e-57 193.9 0.7 3.4e-29 102.2 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF3328) SH3_9 PF14604.6 KXT01280.1 - 0.073 12.9 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain SH3_1 PF00018.28 KXT01280.1 - 0.35 10.5 0.0 0.35 10.5 0.0 2.0 3 0 0 3 3 3 0 SH3 domain Band_7 PF01145.25 KXT01285.1 - 3.8e-16 59.6 0.2 3.8e-16 59.6 0.2 3.0 3 1 0 3 3 3 1 SPFH domain / Band 7 family FIT1_2 PF17357.2 KXT01285.1 - 0.18 11.9 1.7 0.34 11.0 0.0 2.2 2 1 0 2 2 2 0 Facilitor Of iron transport 1 and 2 Filament PF00038.21 KXT01286.1 - 0.0081 15.8 9.1 0.0097 15.5 9.1 1.0 1 0 0 1 1 1 1 Intermediate filament protein CENP-F_leu_zip PF10473.9 KXT01286.1 - 0.0084 16.1 11.8 0.011 15.8 11.8 1.1 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FliG_M PF14841.6 KXT01286.1 - 0.013 15.7 0.1 0.47 10.7 0.0 2.4 2 1 0 2 2 2 0 FliG middle domain Mis14 PF08641.12 KXT01286.1 - 0.019 15.3 9.7 0.024 14.9 9.7 1.1 1 0 0 1 1 1 0 Kinetochore protein Mis14 like MutL_C PF08676.11 KXT01286.1 - 0.026 14.3 2.9 0.54 10.0 0.1 2.1 1 1 1 2 2 2 0 MutL C terminal dimerisation domain KASH_CCD PF14662.6 KXT01286.1 - 0.026 14.3 11.1 0.032 14.0 11.1 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH GAS PF13851.6 KXT01286.1 - 0.035 13.4 11.8 0.063 12.6 7.0 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Muted PF14942.6 KXT01286.1 - 0.062 13.6 10.7 0.081 13.3 10.7 1.1 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein PolC_DP2 PF03833.13 KXT01286.1 - 0.067 11.1 2.8 0.072 11.0 2.8 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 SHE3 PF17078.5 KXT01286.1 - 0.082 12.6 6.3 0.11 12.2 6.3 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 LXG PF04740.12 KXT01286.1 - 0.084 12.6 4.8 0.12 12.1 4.8 1.1 1 0 0 1 1 1 0 LXG domain of WXG superfamily Atg14 PF10186.9 KXT01286.1 - 0.096 11.7 8.5 0.11 11.5 8.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Leu_zip PF15294.6 KXT01286.1 - 0.12 11.9 7.9 0.15 11.5 7.9 1.1 1 0 0 1 1 1 0 Leucine zipper Exonuc_VII_L PF02601.15 KXT01286.1 - 0.14 11.7 8.1 0.15 11.6 8.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit FTA4 PF13093.6 KXT01286.1 - 0.14 12.0 9.0 0.21 11.4 9.0 1.2 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 IFT20 PF14931.6 KXT01286.1 - 0.35 11.1 8.4 0.46 10.7 8.4 1.2 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 HAUS-augmin3 PF14932.6 KXT01286.1 - 0.41 10.2 13.0 0.51 9.9 13.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 TMPIT PF07851.13 KXT01286.1 - 0.49 9.6 5.9 0.56 9.4 5.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein WXG100 PF06013.12 KXT01286.1 - 0.49 10.7 14.9 0.3 11.4 8.1 2.2 1 1 1 2 2 2 0 Proteins of 100 residues with WXG Tfb4 PF03850.14 KXT01286.1 - 0.71 9.3 3.3 0.83 9.1 3.3 1.1 1 0 0 1 1 1 0 Transcription factor Tfb4 OEP PF02321.18 KXT01286.1 - 0.74 9.6 15.6 0.17 11.7 7.9 2.1 1 1 1 2 2 2 0 Outer membrane efflux protein APG6_N PF17675.1 KXT01286.1 - 0.84 10.2 15.7 1.3 9.5 15.7 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region Spore_III_AB PF09548.10 KXT01286.1 - 0.86 9.7 6.0 4 7.5 5.7 1.9 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Spc7 PF08317.11 KXT01286.1 - 1 8.1 12.5 1.3 7.9 12.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3584 PF12128.8 KXT01286.1 - 1.1 6.6 15.3 1.3 6.5 15.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) GvpL_GvpF PF06386.11 KXT01286.1 - 1.4 8.8 9.5 1.7 8.5 9.5 1.1 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF724 PF05266.14 KXT01286.1 - 1.5 8.7 8.1 1.9 8.3 8.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF4407 PF14362.6 KXT01286.1 - 1.5 8.1 9.5 1.8 7.8 9.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ADIP PF11559.8 KXT01286.1 - 1.5 8.9 15.1 1.9 8.6 13.3 1.4 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding FUSC PF04632.12 KXT01286.1 - 1.7 7.1 9.0 1.7 7.1 9.0 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family CCDC-167 PF15188.6 KXT01286.1 - 2.5 8.5 8.8 1.9 8.9 6.7 2.0 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 YabA PF06156.13 KXT01286.1 - 2.6 8.7 6.8 1.9 9.2 4.7 1.8 1 1 1 2 2 2 0 Initiation control protein YabA Nup88 PF10168.9 KXT01286.1 - 3.5 5.3 8.2 4 5.1 8.2 1.0 1 0 0 1 1 1 0 Nuclear pore component V_ATPase_I PF01496.19 KXT01286.1 - 5 4.9 6.8 5.7 4.7 6.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family UPF0242 PF06785.11 KXT01286.1 - 8.1 6.5 13.4 43 4.1 13.4 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ZapB PF06005.12 KXT01286.1 - 9.4 6.8 16.7 13 6.3 2.0 2.4 1 1 1 2 2 2 0 Cell division protein ZapB FSH1 PF03959.13 KXT01287.1 - 1.4e-48 165.3 0.0 1.9e-48 164.9 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 KXT01287.1 - 0.064 12.9 0.0 0.49 10.0 0.0 2.0 1 1 0 2 2 2 0 alpha/beta hydrolase fold Mago-bind PF09282.10 KXT01288.1 - 2.9e-15 55.8 2.5 6.9e-15 54.6 2.5 1.7 1 0 0 1 1 1 1 Mago binding DUF4407 PF14362.6 KXT01288.1 - 4.4 6.6 8.6 4.8 6.4 8.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Med4 PF10018.9 KXT01289.1 - 9.1e-26 90.7 4.0 1.7e-25 89.9 4.0 1.3 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Mito_fiss_reg PF05308.11 KXT01289.1 - 0.014 15.5 1.0 0.027 14.6 1.0 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator GCR PF02155.15 KXT01289.1 - 0.051 12.6 0.2 0.09 11.8 0.2 1.3 1 0 0 1 1 1 0 Glucocorticoid receptor HsbA PF12296.8 KXT01289.1 - 0.09 13.2 2.6 0.45 10.9 2.7 2.2 1 1 0 1 1 1 0 Hydrophobic surface binding protein A OmpH PF03938.14 KXT01289.1 - 6.1 7.2 11.3 5.2 7.4 0.6 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Nop53 PF07767.11 KXT01289.1 - 6.3 6.1 9.0 1.1 8.6 0.3 2.1 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) CAP_N PF01213.19 KXT01289.1 - 8.2 5.8 8.2 1.1 8.7 3.3 1.9 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal MFS_1 PF07690.16 KXT01290.1 - 9.6e-40 136.6 27.1 9.6e-40 136.6 27.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXT01290.1 - 9.8e-11 41.2 6.2 9.8e-11 41.2 6.2 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KXT01290.1 - 7e-05 21.4 4.0 7e-05 21.4 4.0 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) BT1 PF03092.16 KXT01290.1 - 0.00047 18.5 2.0 0.00047 18.5 2.0 2.2 1 1 1 2 2 2 1 BT1 family Spore_III_AF PF09581.10 KXT01290.1 - 0.21 11.6 0.2 0.36 10.8 0.2 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) LapA_dom PF06305.11 KXT01290.1 - 8.4 6.3 6.1 6.7 6.6 1.6 3.3 2 1 1 3 3 3 0 Lipopolysaccharide assembly protein A domain UCR_UQCRX_QCR9 PF05365.12 KXT01294.1 - 1.7e-23 82.3 1.5 3.3e-23 81.4 1.5 1.5 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like zf-UBR PF02207.20 KXT01294.1 - 7.8e-18 64.4 18.7 7.8e-18 64.4 18.7 2.8 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 KXT01294.1 - 8.2e-08 31.9 0.5 2.8e-07 30.2 0.1 2.2 2 0 0 2 2 2 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_5 PF14634.6 KXT01294.1 - 0.01 15.8 0.8 0.01 15.8 0.8 4.4 3 1 1 4 4 4 0 zinc-RING finger domain zf-RING_2 PF13639.6 KXT01294.1 - 0.023 15.0 0.7 0.023 15.0 0.7 4.5 4 1 0 4 4 4 0 Ring finger domain AA_permease_2 PF13520.6 KXT01296.1 - 8.8e-68 229.1 46.6 1e-67 228.8 46.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXT01296.1 - 2.3e-18 66.0 39.3 2.9e-18 65.7 39.3 1.1 1 0 0 1 1 1 1 Amino acid permease Cu_amine_oxid PF01179.20 KXT01297.1 - 8.3e-166 551.9 0.0 1e-165 551.6 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KXT01297.1 - 4.7e-05 23.7 0.0 0.00013 22.3 0.0 1.7 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KXT01297.1 - 0.0041 17.3 0.2 0.018 15.3 0.0 2.2 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain TP_methylase PF00590.20 KXT01298.1 - 3.3e-24 86.0 0.6 7.3e-24 84.9 0.6 1.6 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases RRM_1 PF00076.22 KXT01299.1 - 1.5e-33 114.5 0.3 1.2e-16 60.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXT01299.1 - 1e-09 38.4 0.2 0.00098 19.2 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KXT01299.1 - 0.0063 16.5 0.0 0.95 9.5 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KXT01299.1 - 0.017 15.2 0.0 2.2 8.4 0.0 2.4 2 0 0 2 2 2 0 RNA binding motif TFIIA PF03153.13 KXT01299.1 - 1.5 8.7 11.5 1.9 8.4 11.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RRM_1 PF00076.22 KXT01301.1 - 3.9e-33 113.1 0.3 2e-16 59.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXT01301.1 - 3e-10 40.1 0.1 0.00018 21.6 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KXT01301.1 - 0.016 15.2 0.0 1.5 8.9 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KXT01301.1 - 0.036 14.1 0.0 3.3 7.8 0.0 2.4 2 0 0 2 2 2 0 RNA binding motif dCMP_cyt_deam_1 PF00383.23 KXT01302.1 - 6.3e-26 90.2 1.0 1.4e-25 89.1 1.0 1.6 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KXT01302.1 - 4.3e-09 36.2 0.1 7.5e-09 35.5 0.1 1.3 1 0 0 1 1 1 1 MafB19-like deaminase Prok-E2_A PF14457.6 KXT01302.1 - 0.19 11.3 1.7 1.6 8.3 0.1 2.3 2 0 0 2 2 2 0 Prokaryotic E2 family A Hep_59 PF07052.11 KXT01303.1 - 0.0028 18.4 3.1 0.0028 18.4 0.6 2.3 2 1 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 Pannexin_like PF12534.8 KXT01303.1 - 0.15 11.1 1.0 0.22 10.6 1.0 1.2 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Ribosomal_L27A PF00828.19 KXT01304.1 - 1.4e-21 77.4 0.0 2.2e-21 76.9 0.0 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ribosomal_S18 PF01084.20 KXT01305.1 - 3.4e-13 49.6 0.0 2.7e-12 46.7 0.0 2.5 3 0 0 3 3 3 1 Ribosomal protein S18 SR-25 PF10500.9 KXT01305.1 - 0.0087 15.7 7.3 0.012 15.2 7.3 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein ASFV_J13L PF05568.11 KXT01305.1 - 0.044 13.5 2.7 0.064 13.0 2.7 1.2 1 0 0 1 1 1 0 African swine fever virus J13L protein GATase_4 PF13230.6 KXT01306.1 - 0.089 11.7 0.2 0.099 11.5 0.2 1.1 1 0 0 1 1 1 0 Glutamine amidotransferases class-II zf-CCCH_4 PF18044.1 KXT01307.1 - 3.9e-12 45.7 7.3 1.9e-06 27.5 1.9 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH PF00642.24 KXT01307.1 - 3.8e-08 33.0 8.7 8e-05 22.4 0.7 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KXT01307.1 - 8e-07 28.9 17.6 5.7e-06 26.2 1.9 2.4 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 KXT01307.1 - 3.2e-06 27.8 8.8 0.0073 17.0 0.4 2.4 1 1 1 2 2 2 2 Torus domain zf-CCCH_3 PF15663.5 KXT01307.1 - 0.0021 18.2 2.4 0.0038 17.4 2.4 1.3 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 KXT01307.1 - 0.013 15.9 13.3 0.078 13.5 1.9 2.4 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf_CCCH_5 PF18384.1 KXT01307.1 - 1.8 8.7 8.6 3.3 7.9 2.4 2.4 2 0 0 2 2 2 0 Unkempt Zinc finger domain 1 (Znf1) VID27 PF08553.10 KXT01308.1 - 7.8e-191 633.7 0.1 1.9e-190 632.5 0.0 1.6 2 0 0 2 2 2 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 KXT01308.1 - 7.1e-69 231.1 0.9 7.1e-69 231.1 0.9 2.8 3 0 0 3 3 3 1 VID27 N-terminal region VID27_PH PF17747.1 KXT01308.1 - 1.2e-45 154.2 2.6 1.6e-45 153.9 1.6 1.7 2 0 0 2 2 2 1 VID27 PH-like domain Lipocalin_5 PF13924.6 KXT01309.1 - 3.6e-25 88.4 0.0 5.3e-25 87.9 0.0 1.3 1 0 0 1 1 1 1 Lipocalin-like domain Fringe PF02434.16 KXT01310.1 - 0.00063 19.3 0.7 0.0091 15.5 0.7 2.2 1 1 0 1 1 1 1 Fringe-like RabGAP-TBC PF00566.18 KXT01319.1 - 2.2e-50 171.3 0.0 3.3e-48 164.2 0.0 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain SH3_9 PF14604.6 KXT01320.1 - 2.8e-19 68.7 0.1 4.4e-10 39.2 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KXT01320.1 - 1.8e-18 65.9 0.7 4.3e-08 32.6 0.2 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 KXT01320.1 - 6.9e-11 41.7 0.0 2.4e-05 23.9 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain hSH3 PF14603.6 KXT01320.1 - 0.0068 16.8 0.0 0.4 11.1 0.0 2.2 2 0 0 2 2 2 1 Helically-extended SH3 domain Ppnp PF06865.11 KXT01320.1 - 0.038 14.4 0.0 0.81 10.2 0.0 2.2 2 0 0 2 2 2 0 Pyrimidine/purine nucleoside phosphorylase SH3_3 PF08239.11 KXT01320.1 - 0.057 13.7 0.0 1.2 9.5 0.0 2.5 2 0 0 2 2 2 0 Bacterial SH3 domain Fasciclin PF02469.22 KXT01321.1 - 2.9e-43 147.1 5.0 3.6e-25 88.6 2.0 2.2 2 0 0 2 2 2 2 Fasciclin domain FMO-like PF00743.19 KXT01322.1 - 8.5e-15 54.2 0.0 2.2e-14 52.8 0.0 1.6 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KXT01322.1 - 1.1e-14 54.4 0.0 5.7e-12 45.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXT01322.1 - 6.1e-09 35.5 0.0 2.3e-07 30.3 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KXT01322.1 - 2.8e-08 33.4 0.0 6.4e-08 32.2 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXT01322.1 - 9.3e-08 32.2 0.1 1.4e-06 28.5 0.0 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXT01322.1 - 0.0021 17.7 4.6 0.15 11.6 2.5 3.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXT01322.1 - 0.0038 16.4 0.0 0.0084 15.2 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KXT01322.1 - 0.012 14.9 0.1 0.13 11.5 0.0 2.2 2 0 0 2 2 2 0 Thi4 family FAD_oxidored PF12831.7 KXT01322.1 - 0.056 12.8 0.1 0.13 11.5 0.1 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF5396 PF17374.2 KXT01322.1 - 0.088 10.7 0.0 0.13 10.2 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5396) 2-Hacid_dh_C PF02826.19 KXT01322.1 - 0.18 11.1 0.0 0.39 10.0 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.14 KXT01322.1 - 0.73 8.5 1.8 13 4.4 0.1 2.8 3 0 0 3 3 3 0 HI0933-like protein GIDA PF01134.22 KXT01322.1 - 2.8 6.9 3.9 2 7.4 0.2 2.5 4 0 0 4 4 4 0 Glucose inhibited division protein A PPR_2 PF13041.6 KXT01323.1 - 1.2e-10 41.4 4.6 0.024 14.8 0.0 5.5 7 0 0 7 7 7 3 PPR repeat family PPR PF01535.20 KXT01323.1 - 1.6e-07 31.1 1.0 0.12 12.6 0.0 5.3 7 0 0 7 7 7 2 PPR repeat PPR_3 PF13812.6 KXT01323.1 - 0.00015 21.7 0.1 13 5.9 0.0 5.1 5 0 0 5 5 5 1 Pentatricopeptide repeat domain TPR_14 PF13428.6 KXT01323.1 - 0.0075 17.0 0.0 30 5.8 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF1566 PF07603.11 KXT01323.1 - 0.1 13.0 0.0 0.27 11.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1566) HARE-HTH PF05066.13 KXT01323.1 - 0.14 12.5 0.0 12 6.3 0.0 2.6 2 0 0 2 2 2 0 HB1, ASXL, restriction endonuclease HTH domain DUF4717 PF15838.5 KXT01324.1 - 0.099 12.7 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4717) Amidase PF01425.21 KXT01325.1 - 1.7e-63 215.1 0.0 2.7e-53 181.6 0.0 2.4 2 1 0 2 2 2 2 Amidase GMC_oxred_N PF00732.19 KXT01327.1 - 4.1e-52 177.4 0.0 5.5e-52 177.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXT01327.1 - 1.2e-33 116.7 0.0 2.9e-33 115.4 0.0 1.7 1 1 0 1 1 1 1 GMC oxidoreductase F-box PF00646.33 KXT01328.1 - 0.00029 20.6 0.1 0.00067 19.5 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXT01328.1 - 0.0061 16.4 1.0 0.0087 15.9 0.1 1.8 2 0 0 2 2 2 1 F-box-like DUF1794 PF08768.11 KXT01328.1 - 0.048 13.6 0.0 0.075 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1794) TFIID-18kDa PF02269.16 KXT01330.1 - 1.4e-28 98.7 1.1 6e-28 96.7 0.5 2.0 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit CBFD_NFYB_HMF PF00808.23 KXT01330.1 - 0.014 15.7 0.3 0.051 13.9 0.1 2.0 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ppx-GppA PF02541.16 KXT01331.1 - 5.9e-39 134.2 0.0 1e-38 133.4 0.0 1.3 1 0 0 1 1 1 1 Ppx/GppA phosphatase family Methyltransf_25 PF13649.6 KXT01332.1 - 2e-14 54.0 0.1 6.3e-14 52.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXT01332.1 - 4.1e-14 53.0 0.0 9.4e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXT01332.1 - 2e-09 37.4 0.0 6.2e-09 35.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXT01332.1 - 1.4e-08 35.4 0.1 6.3e-08 33.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXT01332.1 - 4.9e-08 33.0 0.0 9e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXT01332.1 - 7.6e-07 28.7 0.0 2.3e-06 27.1 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KXT01332.1 - 9.1e-05 22.1 0.0 0.00014 21.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KXT01332.1 - 0.00029 20.3 0.1 0.00044 19.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TPMT PF05724.11 KXT01332.1 - 0.0034 17.1 0.0 0.005 16.5 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) ANAPC4_WD40 PF12894.7 KXT01333.1 - 0.00028 21.1 0.0 0.039 14.3 0.0 2.5 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXT01333.1 - 0.046 14.6 1.1 15 6.7 0.0 3.8 4 0 0 4 4 4 0 WD domain, G-beta repeat DSBA PF01323.20 KXT01334.1 - 3.4e-35 121.6 0.0 3.8e-35 121.4 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 KXT01334.1 - 0.0067 16.6 0.2 0.045 13.9 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin CinA PF02464.17 KXT01335.1 - 2.4e-33 114.9 0.0 2.7e-33 114.7 0.0 1.0 1 0 0 1 1 1 1 Competence-damaged protein VATC PF18716.1 KXT01344.1 - 0.0022 17.8 0.1 0.0034 17.2 0.1 1.2 1 0 0 1 1 1 1 Vms1-associating treble clef domain DUF2306 PF10067.9 KXT01344.1 - 0.0042 17.3 0.1 0.0057 16.9 0.1 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2306) eIF-5a PF01287.20 KXT01346.1 - 2.1e-07 30.9 0.1 5.2e-07 29.7 0.1 1.7 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold RCR PF12273.8 KXT01346.1 - 0.11 13.2 0.1 0.31 11.7 0.1 1.8 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red His_Phos_2 PF00328.22 KXT01347.1 - 2.6e-46 158.7 0.0 3e-46 158.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Cnn_1N PF07989.11 KXT01348.1 - 2.1e-06 27.8 10.0 5.9e-06 26.3 10.0 1.8 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 FPP PF05911.11 KXT01348.1 - 0.0022 16.3 5.8 0.0046 15.2 5.8 1.4 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil Csm1_N PF18504.1 KXT01348.1 - 0.45 10.9 12.9 3.9 7.9 4.0 2.8 1 1 1 2 2 2 0 Csm1 N-terminal domain bZIP_1 PF00170.21 KXT01348.1 - 5.6 7.1 8.9 1.7 8.8 0.2 2.9 2 1 0 2 2 2 0 bZIP transcription factor 2OG-FeII_Oxy PF03171.20 KXT01349.1 - 6.4e-13 49.1 0.0 1.2e-12 48.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KXT01349.1 - 8.3e-09 36.2 0.0 1.7e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal SET PF00856.28 KXT01350.1 - 0.056 13.8 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 SET domain ALAD PF00490.21 KXT01351.1 - 4.9e-117 390.6 0.0 7.4e-117 390.0 0.0 1.2 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase zf-RING_2 PF13639.6 KXT01351.1 - 5e-08 33.2 6.7 5e-08 33.2 6.7 3.4 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 KXT01351.1 - 0.0065 16.4 5.3 0.0065 16.4 5.3 3.3 3 0 0 3 3 3 1 zinc-RING finger domain zf-rbx1 PF12678.7 KXT01351.1 - 0.015 15.6 6.2 0.071 13.4 6.2 2.2 1 0 0 1 1 1 0 RING-H2 zinc finger domain FYDLN_acid PF09538.10 KXT01351.1 - 0.022 15.4 3.8 0.05 14.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) PHD PF00628.29 KXT01351.1 - 0.28 11.1 16.3 0.15 12.0 8.3 2.7 2 0 0 2 2 2 0 PHD-finger Baculo_IE-1 PF05290.11 KXT01351.1 - 2.9 7.9 9.1 0.22 11.4 3.1 2.0 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) ACOX PF01756.19 KXT01352.1 - 1.8e-45 154.7 0.6 6.4e-45 152.9 0.2 2.0 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 KXT01352.1 - 1.1e-21 77.6 0.3 4.1e-21 75.8 0.1 2.0 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 KXT01352.1 - 7.4e-11 42.1 0.0 1.7e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KXT01352.1 - 0.00014 22.1 0.2 0.0059 16.8 0.0 2.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Ribosomal_L37ae PF01780.19 KXT01353.1 - 5.8e-42 141.7 10.3 6.5e-42 141.5 10.3 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 KXT01353.1 - 0.0017 18.4 2.9 0.0025 17.9 2.9 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain C1_2 PF03107.16 KXT01353.1 - 0.011 16.0 1.7 0.35 11.2 0.1 2.1 1 1 1 2 2 2 0 C1 domain Nudix_N_2 PF14803.6 KXT01353.1 - 0.015 15.2 1.5 0.78 9.7 0.0 2.3 2 0 0 2 2 2 0 Nudix N-terminal zf-BED PF02892.15 KXT01353.1 - 0.018 15.1 4.0 1.5 8.9 0.4 2.2 1 1 1 2 2 2 0 BED zinc finger Elf1 PF05129.13 KXT01353.1 - 0.025 14.6 1.2 0.038 14.1 1.2 1.4 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like Zn_Tnp_IS1595 PF12760.7 KXT01353.1 - 0.028 14.4 3.0 0.049 13.6 3.0 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.10 KXT01353.1 - 0.032 14.3 1.1 0.075 13.2 1.1 1.6 1 1 0 1 1 1 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 KXT01353.1 - 0.055 13.9 3.0 0.85 10.2 0.7 2.3 1 1 1 2 2 2 0 Zinc-finger double domain DUF1451 PF07295.11 KXT01353.1 - 0.066 13.2 0.7 0.093 12.8 0.7 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain Desulfoferrod_N PF06397.12 KXT01353.1 - 0.076 12.7 1.2 7.4 6.3 0.1 2.2 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain DUF2175 PF09943.9 KXT01353.1 - 0.09 13.1 0.5 3.2 8.1 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) OrfB_Zn_ribbon PF07282.11 KXT01353.1 - 0.21 11.5 2.8 0.32 10.9 2.8 1.4 1 1 0 1 1 1 0 Putative transposase DNA-binding domain HalOD2 PF18547.1 KXT01353.1 - 0.49 10.4 7.1 3.8 7.5 2.0 2.4 1 1 1 2 2 2 0 Halobacterial output domain 2 ADD_ATRX PF17981.1 KXT01353.1 - 0.52 10.2 4.0 5.1 7.0 0.4 2.2 1 1 1 2 2 2 0 Cysteine Rich ADD domain MRNIP PF15749.5 KXT01353.1 - 0.89 10.3 4.8 18 6.1 1.9 2.2 1 1 1 2 2 2 0 MRN-interacting protein zf-CCHC_2 PF13696.6 KXT01353.1 - 3.4 7.6 5.5 16 5.5 0.4 2.2 2 0 0 2 2 2 0 Zinc knuckle Ribosomal_L37ae PF01780.19 KXT01354.1 - 5.8e-42 141.7 10.3 6.5e-42 141.5 10.3 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 KXT01354.1 - 0.0017 18.4 2.9 0.0025 17.9 2.9 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain C1_2 PF03107.16 KXT01354.1 - 0.011 16.0 1.7 0.35 11.2 0.1 2.1 1 1 1 2 2 2 0 C1 domain Nudix_N_2 PF14803.6 KXT01354.1 - 0.015 15.2 1.5 0.78 9.7 0.0 2.3 2 0 0 2 2 2 0 Nudix N-terminal zf-BED PF02892.15 KXT01354.1 - 0.018 15.1 4.0 1.5 8.9 0.4 2.2 1 1 1 2 2 2 0 BED zinc finger Elf1 PF05129.13 KXT01354.1 - 0.025 14.6 1.2 0.038 14.1 1.2 1.4 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like Zn_Tnp_IS1595 PF12760.7 KXT01354.1 - 0.028 14.4 3.0 0.049 13.6 3.0 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.10 KXT01354.1 - 0.032 14.3 1.1 0.075 13.2 1.1 1.6 1 1 0 1 1 1 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 KXT01354.1 - 0.055 13.9 3.0 0.85 10.2 0.7 2.3 1 1 1 2 2 2 0 Zinc-finger double domain DUF1451 PF07295.11 KXT01354.1 - 0.066 13.2 0.7 0.093 12.8 0.7 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain Desulfoferrod_N PF06397.12 KXT01354.1 - 0.076 12.7 1.2 7.4 6.3 0.1 2.2 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain DUF2175 PF09943.9 KXT01354.1 - 0.09 13.1 0.5 3.2 8.1 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) OrfB_Zn_ribbon PF07282.11 KXT01354.1 - 0.21 11.5 2.8 0.32 10.9 2.8 1.4 1 1 0 1 1 1 0 Putative transposase DNA-binding domain HalOD2 PF18547.1 KXT01354.1 - 0.49 10.4 7.1 3.8 7.5 2.0 2.4 1 1 1 2 2 2 0 Halobacterial output domain 2 ADD_ATRX PF17981.1 KXT01354.1 - 0.52 10.2 4.0 5.1 7.0 0.4 2.2 1 1 1 2 2 2 0 Cysteine Rich ADD domain MRNIP PF15749.5 KXT01354.1 - 0.89 10.3 4.8 18 6.1 1.9 2.2 1 1 1 2 2 2 0 MRN-interacting protein zf-CCHC_2 PF13696.6 KXT01354.1 - 3.4 7.6 5.5 16 5.5 0.4 2.2 2 0 0 2 2 2 0 Zinc knuckle zf-RING_2 PF13639.6 KXT01355.1 - 1.4e-07 31.7 1.7 1.4e-07 31.7 1.7 3.6 3 1 1 4 4 3 1 Ring finger domain zf-rbx1 PF12678.7 KXT01355.1 - 1.1e-06 28.8 1.2 1.1e-06 28.8 1.2 2.1 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KXT01355.1 - 7.1e-06 25.8 0.8 7.1e-06 25.8 0.8 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXT01355.1 - 4.1e-05 23.3 3.0 4.1e-05 23.3 3.0 3.0 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 KXT01355.1 - 4.2e-05 23.3 16.3 5.1e-05 23.1 7.5 2.6 2 0 0 2 2 2 1 PHD-finger zf-RING_5 PF14634.6 KXT01355.1 - 8.4e-05 22.4 2.4 0.00016 21.6 0.4 2.5 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KXT01355.1 - 0.00027 20.7 1.1 0.00027 20.7 1.1 2.4 2 1 0 2 2 1 1 Prokaryotic RING finger family 4 PHD_2 PF13831.6 KXT01355.1 - 0.00092 18.7 2.3 0.00092 18.7 2.3 2.0 2 0 0 2 2 2 1 PHD-finger zf-C3HC4_3 PF13920.6 KXT01355.1 - 0.0011 18.8 0.9 0.0011 18.8 0.9 3.4 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KXT01355.1 - 0.0031 17.5 0.2 0.0031 17.5 0.2 1.7 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.7 KXT01355.1 - 0.17 11.9 6.8 0.62 10.1 2.4 3.0 1 1 1 2 2 2 0 Double zinc ribbon DUF1289 PF06945.13 KXT01355.1 - 0.43 10.4 5.3 3.1 7.7 1.7 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) Zn_ribbon_17 PF17120.5 KXT01355.1 - 0.49 10.0 14.4 0.25 11.0 1.7 2.5 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type PHF5 PF03660.14 KXT01355.1 - 0.8 9.9 5.4 1.5 9.1 1.9 2.7 1 1 1 2 2 2 0 PHF5-like protein YL1 PF05764.13 KXT01356.1 - 6.7e-48 163.9 39.8 6.7e-48 163.9 39.8 1.6 2 0 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.11 KXT01356.1 - 2.5e-07 30.3 0.1 4.5e-07 29.5 0.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain CRM1_C PF08767.11 KXT01357.1 - 0.036 13.2 0.0 0.055 12.6 0.0 1.2 1 0 0 1 1 1 0 CRM1 C terminal DUF2564 PF10819.8 KXT01357.1 - 0.25 11.7 5.0 0.85 10.0 5.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2564) CHCH PF06747.13 KXT01358.1 - 0.12 12.5 0.2 0.16 12.2 0.2 1.2 1 0 0 1 1 1 0 CHCH domain Bowman-Birk_leg PF00228.20 KXT01359.1 - 0.09 13.2 3.7 0.09 13.2 3.7 1.6 2 0 0 2 2 2 0 Bowman-Birk serine protease inhibitor family MFS_2 PF13347.6 KXT01360.1 - 3.2e-13 49.0 1.7 1e-12 47.4 1.7 1.9 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.16 KXT01360.1 - 1.3e-11 44.0 23.0 1.3e-11 44.0 23.0 2.3 2 1 1 3 3 3 1 Major Facilitator Superfamily DUF3039 PF11238.8 KXT01360.1 - 0.01 15.5 0.1 0.021 14.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3039) Aha1_N PF09229.11 KXT01361.1 - 6.2e-38 130.1 1.0 1.3e-37 129.1 1.0 1.6 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 KXT01361.1 - 6.1e-19 68.5 0.3 1.1e-18 67.7 0.3 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein LemA PF04011.12 KXT01361.1 - 0.0043 16.9 0.1 0.011 15.6 0.1 1.7 1 0 0 1 1 1 1 LemA family RmuC PF02646.16 KXT01361.1 - 0.0075 15.4 0.1 0.023 13.9 0.1 1.8 1 0 0 1 1 1 1 RmuC family TolA_bind_tri PF16331.5 KXT01361.1 - 0.048 13.8 0.4 0.12 12.5 0.4 1.6 1 0 0 1 1 1 0 TolA binding protein trimerisation ZapB PF06005.12 KXT01361.1 - 0.094 13.2 3.6 21 5.7 0.1 3.3 3 0 0 3 3 3 0 Cell division protein ZapB DHR10 PF18595.1 KXT01361.1 - 0.096 12.7 2.9 0.1 12.6 0.9 2.0 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain DUF4407 PF14362.6 KXT01361.1 - 0.89 8.9 2.6 0.5 9.7 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) CENP-Q PF13094.6 KXT01361.1 - 9.3 6.4 9.7 5.1 7.3 0.3 3.4 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit adh_short PF00106.25 KXT01362.1 - 4.5e-27 94.8 0.0 9.4e-19 67.6 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXT01362.1 - 1.6e-21 76.9 0.0 5e-13 49.1 0.0 2.4 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Peptidase_C97 PF05903.14 KXT01362.1 - 1.7e-05 24.7 0.1 3.6e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF778 PF05608.12 KXT01362.1 - 0.017 15.5 1.2 0.029 14.7 0.1 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF778) LRAT PF04970.13 KXT01362.1 - 0.019 15.3 2.3 0.38 11.0 2.3 2.6 1 1 0 1 1 1 0 Lecithin retinol acyltransferase F_bP_aldolase PF01116.20 KXT01363.1 - 3e-79 266.4 0.3 3.4e-79 266.2 0.3 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Amidohydro_1 PF01979.20 KXT01363.1 - 0.00031 20.2 0.1 0.0049 16.2 0.1 2.0 1 1 1 2 2 2 1 Amidohydrolase family Beach PF02138.18 KXT01364.1 - 1.2e-117 392.3 0.2 1.9e-117 391.6 0.2 1.3 1 0 0 1 1 1 1 Beige/BEACH domain Na_Ca_ex PF01699.24 KXT01364.1 - 2.5e-28 98.9 21.3 4e-14 52.8 10.4 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein PH_BEACH PF14844.6 KXT01364.1 - 1.3e-09 38.1 1.3 1.9e-09 37.5 0.0 2.0 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 KXT01364.1 - 7.1e-07 29.5 0.0 1.5e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.32 KXT01364.1 - 0.0011 19.8 0.3 1.3 10.0 0.0 4.1 3 0 0 3 3 3 1 WD domain, G-beta repeat MscS_TM PF12794.7 KXT01364.1 - 0.0046 15.9 0.7 0.014 14.3 0.7 1.7 1 0 0 1 1 1 1 Mechanosensitive ion channel inner membrane domain 1 MIG-14_Wnt-bd PF06664.12 KXT01364.1 - 0.27 10.4 9.0 0.012 14.8 1.0 2.3 2 0 0 2 2 2 0 Wnt-binding factor required for Wnt secretion Spt5_N PF11942.8 KXT01364.1 - 0.33 12.0 1.4 1.1 10.3 1.4 1.9 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Cyto_heme_lyase PF01265.17 KXT01365.1 - 1e-39 136.9 9.9 1.4e-37 129.9 9.9 3.0 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase Glyco_hydro_11 PF00457.17 KXT01366.1 - 1.7e-76 255.8 14.8 2e-76 255.6 14.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 W_rich_C PF07483.11 KXT01366.1 - 0.05 13.8 0.2 11 6.3 0.1 2.3 2 0 0 2 2 2 0 Tryptophan-rich Synechocystis species C-terminal domain DEAD PF00270.29 KXT01367.1 - 3.1e-31 108.5 0.0 5.6e-31 107.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXT01367.1 - 4.4e-16 59.2 0.0 3.8e-15 56.2 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXT01367.1 - 0.00012 22.2 0.0 0.00035 20.6 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Alpha-amylase PF00128.24 KXT01368.1 - 3.8e-22 79.3 2.1 5.8e-21 75.4 2.1 2.3 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 KXT01368.1 - 1.4e-14 54.4 0.0 2.5e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KXT01368.1 - 2.1e-06 27.4 0.0 5.2e-06 26.1 0.0 1.6 1 1 1 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KXT01368.1 - 0.017 15.1 0.0 0.063 13.3 0.0 1.9 2 0 0 2 2 2 0 Glycosyltransferase Family 4 LSPR PF06049.12 KXT01368.1 - 6.8 7.0 5.3 18 5.7 1.1 3.1 2 0 0 2 2 2 0 Coagulation Factor V LSPD Repeat p450 PF00067.22 KXT01369.1 - 3.5e-18 65.6 0.0 4.4e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_S8 PF00082.22 KXT01370.1 - 2.3e-35 122.3 11.8 3.5e-35 121.7 11.8 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KXT01370.1 - 1.8e-18 67.0 0.4 4e-18 65.9 0.4 1.7 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF3328 PF11807.8 KXT01371.1 - 2.3e-32 112.5 1.6 3.3e-32 112.0 1.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Tannase PF07519.11 KXT01372.1 - 6.2e-97 325.4 0.0 7.3e-97 325.2 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 KXT01372.1 - 0.0007 18.9 0.0 0.0019 17.5 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KXT01372.1 - 0.0008 18.9 0.0 0.019 14.5 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KXT01372.1 - 0.0031 17.2 0.0 0.0054 16.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KXT01372.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Epimerase PF01370.21 KXT01373.1 - 2.1e-22 79.8 0.0 2.6e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXT01373.1 - 7.4e-17 61.8 0.0 1.6e-16 60.7 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KXT01373.1 - 2.7e-11 43.0 0.0 3.8e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KXT01373.1 - 1.4e-07 30.9 0.0 3.8e-07 29.5 0.0 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KXT01373.1 - 8.3e-06 25.2 0.2 0.13 11.5 0.0 2.7 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 KXT01373.1 - 0.0005 20.0 0.0 0.00068 19.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 KXT01373.1 - 0.0015 18.0 0.0 0.0033 16.9 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase Ldh_1_N PF00056.23 KXT01373.1 - 0.024 14.7 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Zn_clus PF00172.18 KXT01374.1 - 2.4e-06 27.5 12.7 2.4e-06 27.5 12.7 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Alpha-amylase PF00128.24 KXT01375.1 - 7.3e-53 180.3 0.0 1.1e-52 179.7 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 KXT01375.1 - 9.6e-24 83.5 0.0 2.2e-23 82.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) YEATS PF03366.16 KXT01376.1 - 4.4e-26 90.7 0.0 7e-26 90.0 0.0 1.3 1 0 0 1 1 1 1 YEATS family FlxA PF14282.6 KXT01376.1 - 0.0059 16.6 3.0 0.006 16.6 0.2 2.0 2 0 0 2 2 2 1 FlxA-like protein GED PF02212.18 KXT01376.1 - 0.26 11.4 2.2 0.83 9.9 2.2 1.8 1 0 0 1 1 1 0 Dynamin GTPase effector domain MDD_C PF18376.1 KXT01377.1 - 6.7e-62 208.6 0.0 9.5e-62 208.1 0.0 1.2 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 KXT01377.1 - 7.2e-09 35.8 0.6 1.7e-08 34.5 0.6 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain AAT PF03417.16 KXT01379.1 - 3e-26 92.5 0.0 3.6e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase FeoB_N PF02421.18 KXT01379.1 - 0.21 11.1 0.0 0.49 9.9 0.0 1.5 2 0 0 2 2 2 0 Ferrous iron transport protein B Ecl1 PF12855.7 KXT01380.1 - 3.2e-14 54.5 30.2 3.8e-14 54.2 30.2 1.1 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins YacG PF03884.14 KXT01380.1 - 0.0069 16.1 1.7 0.017 14.9 1.7 1.7 1 0 0 1 1 1 1 DNA gyrase inhibitor YacG PH PF00169.29 KXT01381.1 - 1.3e-09 38.5 0.0 3.4e-09 37.2 0.0 1.8 1 0 0 1 1 1 1 PH domain Anillin PF08174.11 KXT01381.1 - 2.4e-05 24.8 0.0 4.9e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Cell division protein anillin PH_9 PF15410.6 KXT01381.1 - 0.06 13.7 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain PH PF00169.29 KXT01382.1 - 1.3e-09 38.5 0.0 3.5e-09 37.1 0.0 1.8 1 0 0 1 1 1 1 PH domain Anillin PF08174.11 KXT01382.1 - 2.4e-05 24.8 0.0 5e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Cell division protein anillin PH_9 PF15410.6 KXT01382.1 - 0.063 13.7 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain DUF3445 PF11927.8 KXT01385.1 - 2.4e-72 243.2 0.0 3.1e-72 242.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) RSB_motif PF16294.5 KXT01386.1 - 2.7e-06 27.6 3.5 0.00016 21.9 0.1 2.6 2 0 0 2 2 2 2 RNSP1-SAP18 binding (RSB) motif SAP PF02037.27 KXT01386.1 - 1e-05 25.1 0.2 1.9e-05 24.3 0.2 1.5 1 0 0 1 1 1 1 SAP domain Pinin_SDK_memA PF04696.13 KXT01386.1 - 0.091 12.8 0.5 0.23 11.5 0.5 1.6 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region FMO-like PF00743.19 KXT01387.1 - 1.1e-14 53.9 0.3 5e-14 51.6 0.2 2.0 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXT01387.1 - 1.8e-13 50.4 0.0 1.8e-12 47.1 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXT01387.1 - 8.5e-13 48.2 0.0 8.6e-11 41.6 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXT01387.1 - 1.1e-09 37.9 0.1 2.8e-05 23.4 0.0 3.3 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KXT01387.1 - 1e-07 32.1 0.0 2.8e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXT01387.1 - 3.7e-07 30.1 0.2 9.9e-06 25.4 0.0 2.7 3 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXT01387.1 - 0.00022 21.7 0.0 1.1 9.8 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KXT01387.1 - 0.00026 21.0 0.3 0.05 13.7 0.0 2.6 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 KXT01387.1 - 0.00053 20.0 0.0 0.011 15.7 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KXT01387.1 - 0.006 15.7 0.1 0.0097 15.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KXT01387.1 - 0.0074 15.6 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 KXT01387.1 - 0.038 13.4 0.0 0.065 12.6 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KXT01387.1 - 0.18 10.5 0.5 0.38 9.4 0.3 1.6 2 0 0 2 2 2 0 HI0933-like protein adh_short PF00106.25 KXT01388.1 - 2.8e-05 23.7 0.0 0.17 11.3 0.0 3.2 2 1 0 2 2 2 2 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 KXT01389.1 - 2.1e-15 57.1 0.1 3.2e-15 56.5 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Aa_trans PF01490.18 KXT01391.1 - 7e-36 123.8 34.8 7.9e-36 123.6 34.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Phage_r1t_holin PF16945.5 KXT01391.1 - 2.2 8.5 7.2 0.25 11.6 1.7 2.3 2 0 0 2 2 2 0 Putative lactococcus lactis phage r1t holin HeLo PF14479.6 KXT01392.1 - 4.5e-44 150.7 0.1 1.2e-43 149.4 0.0 1.7 2 0 0 2 2 2 1 Prion-inhibition and propagation Form_Nir_trans PF01226.17 KXT01393.1 - 5.6e-12 45.5 6.8 1.5e-10 40.9 4.4 2.1 1 1 1 2 2 2 2 Formate/nitrite transporter Sdh_cyt PF01127.22 KXT01408.1 - 4.8e-20 71.8 4.3 6.6e-20 71.4 4.3 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Glyco_transf_25 PF01755.17 KXT01409.1 - 1.9e-05 24.6 0.0 0.00032 20.6 0.0 2.5 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) MFS_1 PF07690.16 KXT01410.1 - 1.7e-44 152.2 22.2 2.4e-41 141.8 12.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXT01410.1 - 3e-10 39.6 0.2 3e-10 39.6 0.2 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KXT01410.1 - 7.4e-05 21.4 2.4 0.00012 20.7 2.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 KXT01410.1 - 0.0017 17.3 1.1 0.01 14.7 0.1 2.7 2 1 0 2 2 2 1 MFS_1 like family YiaAB PF05360.14 KXT01410.1 - 0.0075 16.5 1.5 0.04 14.2 1.5 2.3 1 0 0 1 1 1 1 yiaA/B two helix domain LacY_symp PF01306.19 KXT01410.1 - 0.17 10.6 6.8 0.064 12.0 2.7 2.1 1 1 1 2 2 2 0 LacY proton/sugar symporter MMR_HSR1_Xtn PF16897.5 KXT01411.1 - 2.9e-35 120.5 1.3 2.7e-34 117.4 0.3 2.3 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 KXT01411.1 - 1.2e-20 73.2 0.1 2.2e-20 72.5 0.1 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 KXT01411.1 - 4.7e-20 71.8 0.0 1.1e-19 70.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXT01411.1 - 4.8e-13 48.9 0.0 8.4e-13 48.1 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KXT01411.1 - 0.002 18.2 0.3 0.69 10.0 0.0 2.5 1 1 1 2 2 2 2 Dynamin family MeaB PF03308.16 KXT01411.1 - 0.047 12.7 0.2 0.14 11.1 0.1 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MCM PF00493.23 KXT01411.1 - 0.079 12.0 0.1 0.18 10.8 0.0 1.6 2 0 0 2 2 2 0 MCM P-loop domain RNA_pol_L_2 PF13656.6 KXT01412.1 - 6.8e-30 102.7 0.0 1.3e-29 101.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Transglut_core PF01841.19 KXT01412.1 - 5e-10 39.8 0.1 1.7e-09 38.1 0.1 2.0 2 0 0 2 2 2 1 Transglutaminase-like superfamily RNA_pol_L PF01193.24 KXT01412.1 - 9.2e-10 37.8 0.0 1.6e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain SH3_2 PF07653.17 KXT01412.1 - 1.3e-05 24.8 0.0 2.7e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXT01412.1 - 0.00012 21.6 0.1 0.00029 20.4 0.1 1.7 1 0 0 1 1 1 1 SH3 domain Fungal_trans PF04082.18 KXT01413.1 - 3.9e-07 29.4 0.3 8e-07 28.3 0.3 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT01413.1 - 3.9e-07 30.1 5.5 7.4e-07 29.2 5.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 KXT01414.1 - 1.2e-20 74.0 0.0 2.5e-13 50.0 0.0 2.7 2 2 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXT01414.1 - 1.6e-08 34.2 0.1 1.2e-07 31.3 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase AA_permease PF00324.21 KXT01415.1 - 5.7e-122 407.7 37.3 6.5e-122 407.5 37.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXT01415.1 - 3.6e-28 98.6 41.1 4.4e-28 98.3 41.1 1.1 1 0 0 1 1 1 1 Amino acid permease Ribosomal_L5_C PF00673.21 KXT01417.1 - 9.8e-29 99.4 0.0 6.6e-28 96.7 0.0 2.3 3 0 0 3 3 3 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KXT01417.1 - 1.7e-12 47.5 0.6 3.3e-12 46.6 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L5 Ribosomal_L5_C PF00673.21 KXT01418.1 - 9.8e-29 99.4 0.0 6.6e-28 96.7 0.0 2.3 3 0 0 3 3 3 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KXT01418.1 - 1.7e-12 47.5 0.6 3.3e-12 46.6 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L5 MFS_1 PF07690.16 KXT01419.1 - 6.8e-35 120.6 28.5 1e-34 120.1 28.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KXT01419.1 - 2.7e-05 23.6 8.4 3.6e-05 23.2 4.4 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF1691 PF07950.11 KXT01419.1 - 0.042 14.6 1.3 0.11 13.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1691) EXS PF03124.14 KXT01419.1 - 0.42 9.9 4.1 0.17 11.2 0.4 2.1 2 1 0 2 2 2 0 EXS family Nitroreductase PF00881.24 KXT01420.1 - 3.8e-07 30.3 0.0 5e-06 26.7 0.0 2.0 1 1 0 1 1 1 1 Nitroreductase family Spo12 PF05032.12 KXT01421.1 - 5.9e-10 38.9 0.2 1.5e-09 37.6 0.2 1.7 1 0 0 1 1 1 1 Spo12 family Histone PF00125.24 KXT01423.1 - 1.8e-16 60.7 0.0 2.2e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KXT01423.1 - 1.5e-12 47.0 0.1 3.2e-12 46.0 0.1 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KXT01423.1 - 1.4e-05 25.2 0.0 2e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Glyco_hydro_31 PF01055.26 KXT01424.1 - 9.6e-138 460.1 3.9 1.3e-137 459.6 3.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KXT01424.1 - 2.1e-23 82.4 0.6 9.9e-22 77.0 0.2 2.6 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 KXT01424.1 - 2.7e-09 37.2 0.6 1e-08 35.3 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF5110) MFS_1 PF07690.16 KXT01425.1 - 2.5e-18 66.2 30.9 1.5e-17 63.5 30.9 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 KXT01426.1 - 2.7e-25 89.1 31.9 2.7e-25 89.1 31.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KXT01429.1 - 8e-19 67.8 35.4 1.3e-18 67.1 31.6 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_L2_C PF03947.18 KXT01430.1 - 2.4e-41 140.8 5.1 2.4e-41 140.8 5.1 1.6 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KXT01430.1 - 6.5e-14 51.6 0.3 1.6e-13 50.4 0.3 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Cu-oxidase_3 PF07732.15 KXT01431.1 - 1e-43 148.1 0.2 1e-43 148.1 0.2 3.0 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.22 KXT01431.1 - 1.3e-32 113.2 0.1 2.9e-30 105.5 0.0 2.5 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KXT01431.1 - 2.1e-31 108.5 8.9 9.3e-28 96.7 1.5 3.7 3 1 0 3 3 3 2 Multicopper oxidase Comm PF15957.5 KXT01432.1 - 0.14 12.5 0.0 0.26 11.7 0.0 1.4 1 0 0 1 1 1 0 Commissureless HgmA PF04209.13 KXT01433.1 - 9e-129 429.9 0.0 1.1e-128 429.5 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Ribosomal_L39 PF00832.20 KXT01435.1 - 5.5e-21 73.9 9.4 8.3e-21 73.3 9.4 1.3 1 0 0 1 1 1 1 Ribosomal L39 protein MBOAT_2 PF13813.6 KXT01436.1 - 2.7e-19 69.2 1.6 2.7e-19 69.2 1.6 2.5 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family DKCLD PF08068.12 KXT01437.1 - 5.6e-33 112.8 0.2 2.3e-31 107.7 0.1 2.7 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.18 KXT01437.1 - 1e-22 81.1 6.8 5.3e-21 75.5 0.2 4.0 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KXT01437.1 - 7.9e-22 77.2 0.9 1.5e-21 76.3 0.9 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 KXT01437.1 - 4.6e-20 71.3 1.4 9.5e-20 70.3 1.4 1.6 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 KXT01437.1 - 0.0082 16.4 0.0 0.022 15.0 0.0 1.8 1 0 0 1 1 1 1 UPF0113 PUA domain AP3D1 PF06375.11 KXT01437.1 - 0.23 11.7 14.8 0.46 10.7 14.8 1.5 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Coilin_N PF15862.5 KXT01437.1 - 3.7 7.3 12.7 7.3 6.4 12.7 1.5 1 0 0 1 1 1 0 Coilin N-terminus WHIM1 PF15612.6 KXT01438.1 - 0.0089 15.6 0.0 0.019 14.5 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 DNA_pol_phi PF04931.13 KXT01438.1 - 2.8 6.0 12.8 4 5.4 12.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 KXT01438.1 - 5.7 5.0 14.0 9.7 4.2 14.0 1.3 1 0 0 1 1 1 0 Nop14-like family adh_short PF00106.25 KXT01439.1 - 1.5e-31 109.4 0.0 4.7e-31 107.8 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT01439.1 - 4.9e-23 81.9 0.0 1.2e-22 80.6 0.0 1.6 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT01439.1 - 0.0046 16.9 0.7 0.15 12.0 0.7 2.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXT01439.1 - 0.016 14.6 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family CDH-cyt PF16010.5 KXT01440.1 - 9e-51 172.1 4.5 9e-51 172.1 4.5 2.0 2 0 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 KXT01440.1 - 1.3e-26 93.7 0.0 3.7e-26 92.2 0.0 1.9 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXT01440.1 - 2.2e-25 89.9 0.1 5.5e-25 88.6 0.1 1.7 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KXT01440.1 - 4.5e-07 29.3 0.0 0.0041 16.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KXT01440.1 - 2.6e-05 24.0 0.2 0.0047 16.5 0.1 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXT01440.1 - 8.9e-05 21.9 0.0 0.57 9.4 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXT01440.1 - 0.00068 19.8 0.1 0.002 18.3 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXT01440.1 - 0.00072 18.9 0.0 0.0091 15.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXT01440.1 - 0.0012 17.6 0.0 0.1 11.3 0.0 2.6 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox PF00070.27 KXT01440.1 - 0.021 15.4 0.1 11 6.6 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXT01440.1 - 0.051 12.8 0.4 0.58 9.3 0.2 2.4 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.12 KXT01440.1 - 0.11 11.5 0.1 0.2 10.7 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein SSB PF00436.25 KXT01441.1 - 4.1e-15 55.7 0.0 5.1e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family Fungal_trans PF04082.18 KXT01442.1 - 1.4e-11 43.9 1.5 2.5e-11 43.1 1.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Mito_fiss_reg PF05308.11 KXT01442.1 - 3.9 7.5 18.0 0.16 12.0 8.1 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator TRAPP PF04051.16 KXT01443.1 - 4.3e-44 149.8 0.0 5.5e-44 149.4 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Pyr_redox_2 PF07992.14 KXT01445.1 - 2.9e-26 92.4 0.0 4.2e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXT01445.1 - 2.3e-06 28.1 0.0 2.8e-05 24.6 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXT01445.1 - 0.00083 18.7 0.0 0.0056 16.0 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Maf PF02545.14 KXT01445.1 - 0.035 14.0 0.0 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 Maf-like protein K_oxygenase PF13434.6 KXT01445.1 - 0.1 11.8 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) FokI_C PF02980.16 KXT01447.1 - 0.02 14.9 0.0 0.03 14.3 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease FokI, catalytic domain IGPD PF00475.18 KXT01448.1 - 8.6e-31 107.2 0.1 1.9e-30 106.1 0.1 1.5 2 0 0 2 2 2 1 Imidazoleglycerol-phosphate dehydratase DUF3295 PF11702.8 KXT01449.1 - 0.22 10.8 8.1 0.26 10.6 8.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) tRNA-synt_1e PF01406.19 KXT01452.1 - 9.5e-114 379.8 0.1 1.7e-113 379.0 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 KXT01452.1 - 7.2e-05 21.7 1.1 0.34 9.6 0.0 3.3 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1c PF00749.21 KXT01452.1 - 0.051 12.5 2.6 0.11 11.4 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain DALR_2 PF09190.11 KXT01452.1 - 0.11 13.0 0.0 0.11 13.0 0.0 2.2 2 0 0 2 2 2 0 DALR domain UCH_1 PF13423.6 KXT01453.1 - 2.4e-13 50.4 0.0 1.7e-10 41.0 0.0 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ABM PF03992.16 KXT01455.1 - 1.4e-06 28.3 1.1 0.0027 17.8 0.1 2.3 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase SOR_SNZ PF01680.17 KXT01456.1 - 1.2e-106 355.1 6.8 1.7e-106 354.6 6.8 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 KXT01456.1 - 4.9e-08 32.6 9.7 3.5e-06 26.5 1.1 2.5 2 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 KXT01456.1 - 0.00014 21.1 0.5 0.018 14.2 0.1 2.5 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.14 KXT01456.1 - 0.00042 19.6 0.2 0.0047 16.1 0.0 2.4 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.21 KXT01456.1 - 0.00056 19.4 0.2 0.048 13.1 0.1 2.8 2 1 1 3 3 3 2 Histidine biosynthesis protein TetR_C_27 PF17935.1 KXT01456.1 - 0.00082 19.4 0.0 0.0027 17.8 0.0 1.8 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain IGPS PF00218.21 KXT01456.1 - 0.00088 18.5 0.1 0.0077 15.4 0.0 2.2 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase FMN_dh PF01070.18 KXT01456.1 - 0.0033 16.5 0.2 0.027 13.5 0.0 2.1 2 0 0 2 2 2 1 FMN-dependent dehydrogenase TMP-TENI PF02581.17 KXT01456.1 - 0.018 14.4 0.7 0.11 11.8 0.2 2.4 2 1 0 2 2 2 0 Thiamine monophosphate synthase ApoL PF05461.11 KXT01456.1 - 3.7 6.8 8.4 0.17 11.1 1.1 2.1 2 0 0 2 2 2 0 Apolipoprotein L CBFD_NFYB_HMF PF00808.23 KXT01459.1 - 3.5e-19 68.8 0.5 4.8e-19 68.4 0.5 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXT01459.1 - 1.1e-14 54.9 0.4 2e-14 54.1 0.4 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 KXT01459.1 - 0.047 14.0 0.2 0.098 13.0 0.1 1.6 2 0 0 2 2 2 0 CENP-S associating Centromere protein X CBFD_NFYB_HMF PF00808.23 KXT01460.1 - 3.5e-19 68.8 0.5 4.8e-19 68.4 0.5 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXT01460.1 - 1.1e-14 54.9 0.4 2e-14 54.1 0.4 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 KXT01460.1 - 0.047 14.0 0.2 0.098 13.0 0.1 1.6 2 0 0 2 2 2 0 CENP-S associating Centromere protein X P5-ATPase PF12409.8 KXT01461.1 - 4.7e-41 139.8 0.3 2.5e-40 137.5 0.1 2.2 2 0 0 2 2 2 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 KXT01461.1 - 1.1e-30 106.5 0.2 5.9e-30 104.1 0.0 2.2 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KXT01461.1 - 4e-15 56.7 0.1 5.9e-07 30.0 0.0 3.2 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 KXT01461.1 - 9.3e-07 28.7 3.9 9.3e-07 28.7 3.9 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KXT01461.1 - 0.0055 16.8 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KXT01461.1 - 0.0077 16.0 0.2 1.9 8.2 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXT01461.1 - 0.013 15.2 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus PH PF00169.29 KXT01463.1 - 0.0021 18.5 0.2 0.0045 17.5 0.2 1.5 1 0 0 1 1 1 1 PH domain Pkinase PF00069.25 KXT01464.1 - 5.7e-49 166.8 0.0 9.7e-49 166.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT01464.1 - 6e-28 97.8 0.0 9.1e-28 97.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXT01464.1 - 0.007 15.7 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like SARAF PF06682.12 KXT01464.1 - 1.3 8.6 5.0 2.5 7.7 5.0 1.4 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis SNF2_N PF00176.23 KXT01465.1 - 9.6e-75 251.5 1.1 9.6e-75 251.5 1.1 2.4 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.25 KXT01465.1 - 7.7e-24 83.6 0.4 4.1e-23 81.2 0.4 2.3 2 0 0 2 2 2 1 Bromodomain Helicase_C PF00271.31 KXT01465.1 - 1.4e-22 80.1 1.5 1.8e-20 73.3 0.0 3.6 3 1 1 4 4 4 1 Helicase conserved C-terminal domain HSA PF07529.13 KXT01465.1 - 2.4e-20 72.6 10.9 2.4e-20 72.6 10.9 4.3 4 1 1 5 5 5 1 HSA SnAC PF14619.6 KXT01465.1 - 3.2e-12 46.9 0.8 3.2e-12 46.9 0.8 3.2 3 0 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex ResIII PF04851.15 KXT01465.1 - 4.5e-11 43.0 2.6 8.1e-11 42.2 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit QLQ PF08880.11 KXT01465.1 - 1.1e-05 25.0 0.5 3.8e-05 23.3 0.5 2.0 1 0 0 1 1 1 1 QLQ LRR_6 PF13516.6 KXT01466.1 - 0.15 12.2 0.2 0.5 10.5 0.2 2.0 1 0 0 1 1 1 0 Leucine Rich repeat Transp_cyt_pur PF02133.15 KXT01467.1 - 7e-91 305.2 40.6 8.5e-91 304.9 40.6 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin CoA_transf_3 PF02515.17 KXT01468.1 - 8.6e-65 219.2 0.0 1.1e-64 218.9 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III CN_hydrolase PF00795.22 KXT01469.1 - 2.1e-14 53.5 0.0 3.3e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Phage_holin_3_2 PF04550.12 KXT01469.1 - 0.011 16.3 0.1 0.026 15.0 0.1 1.6 1 0 0 1 1 1 0 Phage holin family 2 Ldh_1_N PF00056.23 KXT01470.1 - 8e-45 152.4 0.1 1.1e-44 152.0 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KXT01470.1 - 1.1e-44 152.3 0.0 1.6e-44 151.7 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 KXT01470.1 - 0.0049 15.9 0.0 0.0073 15.3 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KXT01470.1 - 0.04 13.8 0.0 0.24 11.3 0.0 2.2 2 1 0 2 2 2 0 NAD(P)H-binding Glyco_hydro_4 PF02056.16 KXT01470.1 - 0.076 12.6 0.2 0.71 9.4 0.3 2.2 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase Ank_3 PF13606.6 KXT01471.1 - 6.8e-08 32.2 0.6 0.018 15.5 0.0 3.1 3 0 0 3 3 2 2 Ankyrin repeat Ank_4 PF13637.6 KXT01471.1 - 9.3e-08 32.5 0.0 2.2e-06 28.1 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXT01471.1 - 6.6e-07 29.8 0.0 2.6e-06 27.9 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KXT01471.1 - 1.1e-05 25.6 0.3 0.035 14.5 0.1 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KXT01471.1 - 0.00057 20.1 0.1 0.37 11.2 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) ExsD PF16806.5 KXT01471.1 - 0.021 14.7 1.8 0.63 9.9 1.1 2.4 2 0 0 2 2 2 0 Antiactivator protein ExsD HAP1_N PF04849.13 KXT01471.1 - 0.055 12.7 9.8 0.013 14.7 6.5 1.6 2 0 0 2 2 2 0 HAP1 N-terminal conserved region F_actin_cap_B PF01115.17 KXT01471.1 - 0.1 12.2 0.4 2.5 7.7 0.0 2.3 2 0 0 2 2 2 0 F-actin capping protein, beta subunit DUF2009 PF09418.10 KXT01471.1 - 0.11 11.5 3.2 0.2 10.7 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) UPF0242 PF06785.11 KXT01471.1 - 0.38 10.8 8.5 0.85 9.7 8.5 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ALMT PF11744.8 KXT01471.1 - 0.39 9.5 3.9 0.55 9.0 3.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Atg14 PF10186.9 KXT01471.1 - 0.55 9.3 12.1 0.54 9.3 7.1 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 TPR_12 PF13424.6 KXT01471.1 - 0.82 10.0 5.7 0.29 11.4 0.3 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXT01471.1 - 1.6 9.1 11.5 17 5.8 0.0 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat Fib_alpha PF08702.10 KXT01471.1 - 1.8 8.7 10.7 12 6.1 9.6 2.5 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DHR10 PF18595.1 KXT01471.1 - 5 7.2 18.1 2.8 8.0 13.9 2.6 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Piwi PF02171.17 KXT01473.1 - 2.1e-64 217.6 0.0 1e-31 110.4 0.0 2.2 2 0 0 2 2 2 2 Piwi domain ArgoL2 PF16488.5 KXT01473.1 - 2.2e-06 27.9 0.0 4.7e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoL1 PF08699.10 KXT01473.1 - 0.0001 21.9 0.1 0.00026 20.6 0.1 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.5 KXT01473.1 - 0.0024 18.5 0.0 0.0053 17.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute Lysozyme_like PF13702.6 KXT01473.1 - 0.54 9.9 2.0 20 4.9 0.1 3.1 3 0 0 3 3 3 0 Lysozyme-like Piwi PF02171.17 KXT01474.1 - 2.4e-64 217.5 0.0 1.1e-31 110.2 0.0 2.3 2 0 0 2 2 2 2 Piwi domain ArgoL2 PF16488.5 KXT01474.1 - 2.3e-06 27.8 0.0 5e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoL1 PF08699.10 KXT01474.1 - 0.00011 21.8 0.1 0.00028 20.5 0.1 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.5 KXT01474.1 - 0.0026 18.4 0.0 0.0057 17.3 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute Lysozyme_like PF13702.6 KXT01474.1 - 0.8 9.4 2.4 21 4.8 0.1 3.0 3 0 0 3 3 3 0 Lysozyme-like LysM PF01476.20 KXT01475.1 - 2.3e-12 46.8 0.0 3.6e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 LysM domain NUDIX PF00293.28 KXT01476.1 - 1e-18 67.7 0.0 1.2e-18 67.4 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain DUF1688 PF07958.11 KXT01477.1 - 1.8e-185 616.7 0.0 2e-185 616.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) NDK PF00334.19 KXT01478.1 - 1.6e-53 180.4 0.0 1.9e-53 180.1 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase DUF3091 PF11291.8 KXT01478.1 - 0.084 13.0 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3091) Sacchrp_dh_C PF16653.5 KXT01479.1 - 1.6e-91 307.1 0.0 4.7e-91 305.6 0.0 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 KXT01479.1 - 9.2e-25 87.4 1.2 1.4e-24 86.8 1.2 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KXT01479.1 - 3.4e-07 30.4 1.3 4.8e-06 26.7 1.3 2.1 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 KXT01479.1 - 1.6e-05 24.9 0.5 2.7e-05 24.2 0.5 1.3 1 0 0 1 1 1 1 NAD(P)H-binding IlvN PF07991.12 KXT01479.1 - 0.00019 21.1 0.1 0.00056 19.5 0.1 1.7 2 1 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 KXT01479.1 - 0.0034 17.9 0.4 0.0065 17.0 0.4 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.22 KXT01479.1 - 0.041 14.7 0.1 0.069 14.0 0.1 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Epimerase PF01370.21 KXT01479.1 - 0.071 12.6 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.6 KXT01479.1 - 0.16 12.4 0.4 0.36 11.3 0.4 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF2325 PF10087.9 KXT01479.1 - 0.19 11.9 0.3 0.47 10.6 0.3 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) ACT_7 PF13840.6 KXT01480.1 - 4.4e-26 90.5 0.0 1.9e-16 59.6 0.0 2.5 2 0 0 2 2 2 2 ACT domain Abhydrolase_6 PF12697.7 KXT01481.1 - 2.8e-17 64.1 0.0 3.3e-17 63.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXT01481.1 - 0.028 13.7 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 KXT01481.1 - 0.073 12.8 0.0 0.21 11.3 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family Synapsin PF02078.16 KXT01481.1 - 0.12 12.6 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Synapsin, N-terminal domain Defensin_beta PF00711.19 KXT01483.1 - 1 9.4 7.5 14 5.8 0.5 3.7 3 1 1 4 4 4 0 Beta defensin DUF2293 PF10056.9 KXT01486.1 - 2.3e-31 107.9 0.3 6.1e-31 106.5 0.3 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) CUE PF02845.16 KXT01486.1 - 0.061 13.0 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 CUE domain DUF2293 PF10056.9 KXT01487.1 - 2.3e-31 107.9 0.3 6e-31 106.5 0.3 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) CUE PF02845.16 KXT01487.1 - 0.06 13.1 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 CUE domain SNF2_N PF00176.23 KXT01488.1 - 3.5e-63 213.5 0.5 3.3e-61 207.0 0.5 3.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXT01488.1 - 4.1e-16 59.3 0.2 1e-15 58.0 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXT01488.1 - 4e-05 23.7 0.8 0.0001 22.4 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KXT01488.1 - 9.6e-05 22.2 0.0 0.00024 20.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Solute_trans_a PF03619.16 KXT01489.1 - 9.4e-39 133.5 7.7 1.2e-38 133.2 7.7 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha TPP_enzyme_N PF02776.18 KXT01491.1 - 1.1e-26 93.5 0.2 1.2e-26 93.4 0.2 1.0 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KXT01492.1 - 1.4e-37 128.8 0.0 9.6e-37 126.1 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KXT01492.1 - 2.8e-26 91.9 0.0 4.9e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N PF02776.18 KXT01492.1 - 1.1e-12 48.0 0.0 3.7e-12 46.2 0.1 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain CO_dh PF02552.16 KXT01492.1 - 0.085 12.6 0.0 0.28 10.9 0.0 1.7 2 0 0 2 2 2 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit TPP_enzyme_N PF02776.18 KXT01493.1 - 1.5e-45 154.9 0.6 6e-45 152.9 1.1 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KXT01493.1 - 8.3e-39 132.8 0.3 1.3e-36 125.7 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KXT01493.1 - 3.7e-26 91.5 0.0 6.5e-26 90.7 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain CO_dh PF02552.16 KXT01493.1 - 0.11 12.2 0.0 0.34 10.7 0.0 1.7 2 0 0 2 2 2 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit MFS_1 PF07690.16 KXT01494.1 - 2.2e-36 125.5 41.5 2.2e-36 125.5 41.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXT01494.1 - 2.6e-11 43.0 31.6 7.6e-11 41.5 31.6 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KXT01494.1 - 8.3e-07 27.8 5.5 8.3e-07 27.8 5.5 2.3 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 KXT01494.1 - 2.9e-05 23.5 4.2 2.9e-05 23.5 4.2 2.3 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF4112 PF13430.6 KXT01494.1 - 0.84 9.9 4.3 1.9 8.8 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4112) SNF2_N PF00176.23 KXT01495.1 - 1.2e-56 192.0 0.1 1.8e-56 191.4 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 KXT01495.1 - 8.7e-21 73.6 3.7 2.8e-13 49.5 0.3 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 KXT01495.1 - 1.5e-18 67.1 0.0 3.2e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4208 PF13907.6 KXT01495.1 - 6.4e-18 65.0 0.0 2.4e-17 63.1 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) HDA2-3 PF11496.8 KXT01495.1 - 3.1e-06 26.6 0.5 1e-05 24.9 0.0 2.1 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 KXT01495.1 - 7e-06 26.2 0.0 2.7e-05 24.2 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Cdh1_DBD_1 PF18196.1 KXT01495.1 - 2.9e-05 24.4 20.4 0.0015 18.9 0.5 4.8 3 1 1 4 4 4 2 Chromodomain helicase DNA-binding domain 1 SLIDE PF09111.10 KXT01495.1 - 0.0073 16.3 0.7 0.046 13.8 0.0 2.7 2 0 0 2 2 2 1 SLIDE CHDCT2 PF08074.11 KXT01495.1 - 0.071 13.3 0.3 0.42 10.8 0.0 2.3 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain S4 PF01479.25 KXT01495.1 - 0.18 11.5 0.4 4 7.2 0.0 2.5 2 0 0 2 2 2 0 S4 domain CDH1_2_SANT_HL1 PF18375.1 KXT01495.1 - 1.7 9.4 4.6 0.96 10.2 1.0 2.7 2 0 0 2 2 1 0 CDH1/2 SANT-Helical linker 1 NUC173 PF08161.12 KXT01496.1 - 1.5e-82 276.2 0.2 1.2e-77 260.1 0.0 2.9 2 0 0 2 2 2 2 NUC173 domain CdiI_2 PF18593.1 KXT01496.1 - 0.072 13.8 0.3 10 6.9 0.0 3.8 5 0 0 5 5 5 0 CdiI immunity protein Vac14_Fab1_bd PF12755.7 KXT01496.1 - 0.11 13.1 0.0 41 4.9 0.0 4.0 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region GvpK PF05121.12 KXT01496.1 - 0.29 11.2 1.6 0.51 10.4 0.4 2.1 2 0 0 2 2 2 0 Gas vesicle protein K MMS19_C PF12460.8 KXT01496.1 - 0.79 8.8 17.8 11 4.9 0.3 4.5 3 1 0 3 3 3 0 RNAPII transcription regulator C-terminal Methyltransf_24 PF13578.6 KXT01497.1 - 3.9e-06 27.8 0.0 2.8e-05 25.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain AAL_decarboxy PF03306.13 KXT01498.1 - 1.5e-72 243.5 0.0 1.6e-72 243.4 0.0 1.0 1 0 0 1 1 1 1 Alpha-acetolactate decarboxylase BORCS6 PF10157.9 KXT01499.1 - 0.058 13.6 0.4 0.19 11.9 0.2 1.9 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 6 AAA PF00004.29 KXT01500.1 - 3.1e-16 60.0 0.0 8.3e-16 58.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 KXT01500.1 - 3.3e-13 49.6 0.0 9.2e-13 48.2 0.0 1.7 1 0 0 1 1 1 1 AAA lid domain AAA_16 PF13191.6 KXT01500.1 - 5.3e-11 43.2 0.0 5.5e-10 39.9 0.0 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXT01500.1 - 2.8e-10 40.6 0.0 4.5e-08 33.4 0.0 2.7 3 0 0 3 3 3 1 AAA domain BAH PF01426.18 KXT01500.1 - 2e-06 27.7 0.0 6.7e-06 26.0 0.0 1.9 1 0 0 1 1 1 1 BAH domain AAA_19 PF13245.6 KXT01500.1 - 0.00051 20.4 0.0 0.0013 19.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KXT01500.1 - 0.011 16.0 0.0 0.03 14.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain Rrn6 PF10214.9 KXT01500.1 - 0.02 13.4 0.1 0.028 13.0 0.1 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor AAA_11 PF13086.6 KXT01500.1 - 0.026 14.3 0.2 0.08 12.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KXT01500.1 - 0.027 14.8 0.0 0.15 12.4 0.0 2.3 2 0 0 2 2 2 0 RNA helicase ssDBP PF17878.1 KXT01500.1 - 0.043 14.0 0.1 0.097 12.9 0.1 1.5 1 0 0 1 1 1 0 Single-stranded DNA-binding protein AAA_30 PF13604.6 KXT01500.1 - 0.06 13.0 0.2 0.17 11.6 0.2 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KXT01500.1 - 0.077 13.5 0.0 0.18 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KXT01500.1 - 0.1 11.8 0.0 0.26 10.5 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 KXT01500.1 - 0.11 12.4 0.0 0.28 11.1 0.0 1.7 1 1 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 KXT01500.1 - 0.13 12.1 0.0 0.74 9.7 0.0 2.1 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_32 PF13654.6 KXT01500.1 - 0.15 10.8 0.0 0.55 9.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KXT01500.1 - 0.18 11.3 0.1 1.4 8.4 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_6 PF12774.7 KXT01500.1 - 0.25 10.3 0.2 0.47 9.4 0.2 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region Forkhead PF00250.18 KXT01501.1 - 1.5e-33 114.9 0.2 2.7e-33 114.1 0.2 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 KXT01501.1 - 3.7e-09 36.8 0.1 6.7e-09 36.0 0.1 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KXT01501.1 - 0.022 15.1 0.0 0.044 14.1 0.0 1.4 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain DUF2756 PF10956.8 KXT01501.1 - 0.084 13.4 3.5 0.22 12.1 3.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2756) CRC_subunit PF08624.10 KXT01502.1 - 1.6e-51 174.3 0.0 2.4e-51 173.7 0.0 1.3 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit F-box-like_2 PF13013.6 KXT01503.1 - 0.0029 17.6 0.0 0.0053 16.7 0.0 1.5 1 0 0 1 1 1 1 F-box-like domain zf-RING_9 PF13901.6 KXT01503.1 - 0.021 14.8 0.3 0.033 14.2 0.3 1.3 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon Rho_Binding PF08912.11 KXT01503.1 - 0.031 15.1 0.0 0.082 13.7 0.0 1.7 1 0 0 1 1 1 0 Rho Binding Ribosomal_L22e PF01776.17 KXT01504.1 - 1.9e-43 147.3 0.1 2.4e-43 147.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal L22e protein family DUF1160 PF06648.11 KXT01504.1 - 0.14 12.2 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1160) OCRE PF17780.1 KXT01505.1 - 2.4 8.3 8.5 1.6 8.8 1.1 2.5 2 0 0 2 2 2 0 OCRE domain ABC_tran PF00005.27 KXT01506.1 - 4.6e-36 124.3 0.0 1e-16 61.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter RLI PF04068.15 KXT01506.1 - 3e-14 52.6 5.5 3e-14 52.6 5.5 2.0 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 KXT01506.1 - 2.5e-11 43.5 1.8 0.0066 15.9 0.0 4.1 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KXT01506.1 - 1.5e-10 41.4 0.7 0.094 12.5 0.1 4.2 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 KXT01506.1 - 1.2e-06 28.6 0.0 0.015 15.2 0.0 2.5 2 1 0 2 2 2 2 Rad17 P-loop domain AAA PF00004.29 KXT01506.1 - 4.5e-06 27.1 0.1 0.016 15.7 0.1 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXT01506.1 - 5.4e-06 26.7 0.0 0.0036 17.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KXT01506.1 - 1.6e-05 24.8 0.1 0.24 11.1 0.0 2.9 2 1 0 3 3 3 2 AAA ATPase domain AAA_16 PF13191.6 KXT01506.1 - 1.7e-05 25.2 0.0 0.11 12.9 0.0 2.4 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KXT01506.1 - 2.9e-05 24.1 0.0 0.18 11.7 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase RNA_helicase PF00910.22 KXT01506.1 - 7.8e-05 23.0 0.5 0.14 12.6 0.0 3.3 4 0 0 4 4 2 1 RNA helicase Fer4 PF00037.27 KXT01506.1 - 0.00014 21.5 3.1 0.00014 21.5 3.1 2.7 3 0 0 3 3 3 1 4Fe-4S binding domain SRP54 PF00448.22 KXT01506.1 - 0.00015 21.4 1.2 0.053 13.1 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_24 PF13479.6 KXT01506.1 - 0.00052 19.8 0.2 0.14 11.8 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KXT01506.1 - 0.00068 19.3 0.1 1.4 8.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_33 PF13671.6 KXT01506.1 - 0.00083 19.5 0.0 0.54 10.4 0.1 2.5 2 0 0 2 2 2 1 AAA domain Fer4_21 PF14697.6 KXT01506.1 - 0.0011 19.1 11.7 0.0022 18.1 11.7 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_7 PF12775.7 KXT01506.1 - 0.0014 18.2 0.1 0.044 13.3 0.1 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_23 PF13476.6 KXT01506.1 - 0.0014 19.2 0.0 0.26 11.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KXT01506.1 - 0.0014 18.6 1.6 0.25 11.3 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_30 PF13604.6 KXT01506.1 - 0.0019 18.0 0.1 0.31 10.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KXT01506.1 - 0.0022 18.5 0.0 3 8.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 KXT01506.1 - 0.0024 17.9 0.1 0.061 13.3 0.1 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Thymidylate_kin PF02223.17 KXT01506.1 - 0.0044 16.7 0.1 3.1 7.4 0.0 2.5 2 0 0 2 2 2 1 Thymidylate kinase NB-ARC PF00931.22 KXT01506.1 - 0.0059 15.8 0.0 0.55 9.4 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain AAA_5 PF07728.14 KXT01506.1 - 0.011 15.7 0.2 0.68 9.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Fer4_6 PF12837.7 KXT01506.1 - 0.012 15.7 13.1 0.031 14.4 2.9 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain AAA_13 PF13166.6 KXT01506.1 - 0.013 14.2 1.4 0.017 13.8 0.0 1.9 3 0 0 3 3 2 0 AAA domain Fer4_10 PF13237.6 KXT01506.1 - 0.016 15.3 1.7 0.016 15.3 1.7 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain AAA_14 PF13173.6 KXT01506.1 - 0.018 15.1 0.1 4.6 7.3 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KXT01506.1 - 0.019 15.2 0.1 5.9 7.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain Fer4_9 PF13187.6 KXT01506.1 - 0.037 14.2 11.1 0.085 13.0 11.1 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 KXT01506.1 - 0.043 14.4 1.4 0.043 14.4 1.4 2.4 1 1 2 3 3 3 0 4Fe-4S dicluster domain VirE PF05272.11 KXT01506.1 - 0.059 13.1 0.0 5.5 6.7 0.0 2.4 2 0 0 2 2 2 0 Virulence-associated protein E MukB PF04310.12 KXT01506.1 - 0.07 12.9 0.1 12 5.6 0.0 2.3 2 0 0 2 2 2 0 MukB N-terminal Rad51 PF08423.11 KXT01506.1 - 0.082 12.2 0.2 0.48 9.6 0.1 2.1 2 0 0 2 2 2 0 Rad51 Fer4_16 PF13484.6 KXT01506.1 - 0.087 13.8 0.3 0.087 13.8 0.3 2.7 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain DnaB_C PF03796.15 KXT01506.1 - 0.1 11.9 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain DUF815 PF05673.13 KXT01506.1 - 0.11 11.7 0.0 9.4 5.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ATPase PF06745.13 KXT01506.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 KaiC CLP1_P PF16575.5 KXT01506.1 - 0.16 11.7 0.3 1.7 8.4 0.0 2.3 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop MeaB PF03308.16 KXT01506.1 - 0.2 10.6 0.1 1.4 7.8 0.0 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PduV-EutP PF10662.9 KXT01506.1 - 0.2 11.4 1.6 0.32 10.7 0.1 2.1 2 0 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 KXT01506.1 - 0.24 11.3 3.1 4.2 7.3 0.1 2.9 3 0 0 3 3 2 0 NTPase MMR_HSR1 PF01926.23 KXT01506.1 - 0.3 11.2 0.8 37 4.5 0.0 2.5 2 1 0 2 2 2 0 50S ribosome-binding GTPase Fer4_8 PF13183.6 KXT01506.1 - 0.31 11.5 6.5 0.38 11.2 0.2 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 KXT01506.1 - 1.7 8.9 9.9 0.25 11.5 1.2 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain GLE1 PF07817.13 KXT01508.1 - 1.3e-26 93.3 0.0 1.3e-26 93.3 0.0 1.9 2 0 0 2 2 2 1 GLE1-like protein eIF-1a PF01176.19 KXT01511.1 - 2.2e-21 75.4 0.0 3.1e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 G-alpha PF00503.20 KXT01512.1 - 5e-120 400.9 1.7 5e-120 400.9 1.7 1.8 2 0 0 2 2 2 1 G-protein alpha subunit Arf PF00025.21 KXT01512.1 - 1.3e-13 50.7 2.0 1.1e-09 38.0 0.1 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family SET PF00856.28 KXT01512.1 - 1.6e-13 51.4 1.1 1e-12 48.8 0.1 2.9 2 1 0 2 2 2 1 SET domain zf-CHC2 PF01807.20 KXT01512.1 - 0.0013 18.5 0.0 0.0049 16.7 0.0 2.0 1 0 0 1 1 1 1 CHC2 zinc finger Gtr1_RagA PF04670.12 KXT01512.1 - 0.063 12.6 2.8 0.69 9.2 0.1 2.7 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region MCM PF00493.23 KXT01512.1 - 0.08 12.0 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain AAA_29 PF13555.6 KXT01512.1 - 0.3 10.9 0.0 0.3 10.9 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain FF PF01846.19 KXT01513.1 - 2.6e-34 117.2 28.6 5.2e-13 48.9 1.7 5.5 5 0 0 5 5 5 4 FF domain WW PF00397.26 KXT01513.1 - 5.5e-16 58.3 16.9 4.1e-09 36.4 0.8 2.9 3 0 0 3 3 3 2 WW domain Glyco_hyd_101C PF17451.2 KXT01513.1 - 0.00038 20.7 4.9 0.065 13.5 0.5 2.9 2 0 0 2 2 2 2 Glycosyl hydrolase 101 beta sandwich domain Vps51 PF08700.11 KXT01513.1 - 7.2 6.8 7.5 0.76 9.9 0.2 2.9 3 0 0 3 3 3 0 Vps51/Vps67 UPF0020 PF01170.18 KXT01514.1 - 2.7e-07 30.5 0.1 5.4e-06 26.2 0.1 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 MethyltransfD12 PF02086.15 KXT01514.1 - 0.09 12.4 0.1 0.39 10.3 0.0 1.9 1 1 1 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase MIS13 PF08202.11 KXT01515.1 - 8.4e-39 133.6 11.4 5.6e-36 124.4 0.2 2.7 3 0 0 3 3 3 2 Mis12-Mtw1 protein family ZapB PF06005.12 KXT01515.1 - 2.4 8.6 6.5 1.4 9.4 0.7 3.0 2 0 0 2 2 2 0 Cell division protein ZapB BPL_N PF09825.9 KXT01515.1 - 6.3 5.8 10.0 7.5 5.5 2.8 2.2 2 0 0 2 2 2 0 Biotin-protein ligase, N terminal DUF4811 PF16069.5 KXT01515.1 - 9.4 6.1 6.8 19 5.1 6.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4811) MIS13 PF08202.11 KXT01516.1 - 8.5e-39 133.6 12.1 5.2e-36 124.5 0.2 2.7 3 0 0 3 3 3 2 Mis12-Mtw1 protein family ZapB PF06005.12 KXT01516.1 - 2.3 8.7 6.5 1.3 9.5 0.7 3.0 2 0 0 2 2 2 0 Cell division protein ZapB BPL_N PF09825.9 KXT01516.1 - 5.8 5.9 10.0 7.2 5.6 2.8 2.2 2 0 0 2 2 2 0 Biotin-protein ligase, N terminal DUF4811 PF16069.5 KXT01516.1 - 8.8 6.2 6.8 18 5.2 6.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4811) COA2 PF17051.5 KXT01517.1 - 3.3e-06 27.1 0.0 6e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome C oxidase assembly factor 2 RNB PF00773.19 KXT01518.1 - 9e-91 304.6 0.2 2.8e-90 303.0 0.1 1.9 2 0 0 2 2 2 1 RNB domain OB_Dis3 PF17849.1 KXT01518.1 - 1.4e-27 95.5 0.0 3.8e-27 94.1 0.0 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 KXT01518.1 - 3e-25 88.3 0.0 1.3e-24 86.3 0.0 2.1 2 0 0 2 2 2 1 DIS3-like exonuclease 2 C terminal CSD2 PF17876.1 KXT01518.1 - 7.3e-06 26.1 0.0 0.0028 17.8 0.0 3.0 2 0 0 2 2 2 2 Cold shock domain Rrp44_CSD1 PF17216.3 KXT01518.1 - 0.00032 20.4 0.8 0.0022 17.8 0.0 2.3 2 0 0 2 2 2 1 Rrp44-like cold shock domain CBFD_NFYB_HMF PF00808.23 KXT01519.1 - 1.6e-10 41.1 0.0 3.2e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 KXT01519.1 - 4.1e-05 23.6 0.0 7.7e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 KXT01519.1 - 0.013 15.8 0.9 0.027 14.8 0.0 2.0 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXT01520.1 - 1.6e-10 41.1 0.0 3.2e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 KXT01520.1 - 4.1e-05 23.6 0.0 7.7e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 KXT01520.1 - 0.013 15.8 0.9 0.027 14.8 0.0 2.0 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 HLH PF00010.26 KXT01521.1 - 5.6e-11 42.2 0.9 1.4e-09 37.7 0.0 3.0 2 1 1 3 3 3 1 Helix-loop-helix DNA-binding domain DFF40 PF09230.10 KXT01521.1 - 0.04 13.5 0.1 0.081 12.5 0.0 1.5 1 1 0 1 1 1 0 DNA fragmentation factor 40 kDa LIM PF00412.22 KXT01522.1 - 3.5e-21 75.2 23.6 8.4e-13 48.4 3.8 3.0 3 0 0 3 3 3 2 LIM domain MFS_5 PF05631.14 KXT01524.1 - 8.2e-65 219.0 9.1 1.3e-64 218.4 9.1 1.2 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 KXT01524.1 - 3.1e-19 69.1 35.4 3.9e-19 68.8 35.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily C2 PF00168.30 KXT01525.1 - 0.068 13.5 0.0 0.092 13.1 0.0 1.4 1 1 0 1 1 1 0 C2 domain WD40 PF00400.32 KXT01526.1 - 2.5e-21 75.5 19.3 3.5e-06 27.7 0.5 7.1 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXT01526.1 - 2.1e-11 44.0 5.1 9e-06 25.9 0.0 3.9 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXT01526.1 - 0.025 13.5 0.0 37 3.1 0.0 3.6 2 2 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 KXT01526.1 - 0.03 12.3 2.7 0.11 10.5 0.1 2.1 2 0 0 2 2 2 0 IKI3 family Spindle_Spc25 PF08234.12 KXT01528.1 - 2.5e-23 82.1 0.2 6.3e-23 80.8 0.0 1.8 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 DUF5094 PF17015.5 KXT01528.1 - 2.5e-05 24.4 0.5 3.8e-05 23.9 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5094) AAA_13 PF13166.6 KXT01528.1 - 0.0052 15.5 9.2 0.0069 15.1 9.2 1.0 1 0 0 1 1 1 1 AAA domain ESM4 PF15952.5 KXT01528.1 - 0.023 15.1 5.5 0.039 14.4 5.5 1.4 1 0 0 1 1 1 0 Enhancer of split M4 family DUF148 PF02520.17 KXT01528.1 - 0.024 14.8 6.3 0.024 14.8 6.3 2.1 1 1 1 2 2 2 0 Domain of unknown function DUF148 AcetDehyd-dimer PF09290.11 KXT01528.1 - 0.067 13.4 1.0 0.11 12.7 1.0 1.4 1 0 0 1 1 1 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation Exonuc_VII_L PF02601.15 KXT01528.1 - 0.081 12.5 9.5 0.11 12.0 9.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF812 PF05667.11 KXT01528.1 - 0.1 11.5 14.5 0.13 11.1 14.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Tup_N PF08581.10 KXT01528.1 - 0.12 12.7 14.2 0.15 12.4 2.0 2.4 1 1 1 2 2 2 0 Tup N-terminal PIN_8 PF18476.1 KXT01528.1 - 0.14 12.0 8.5 0.22 11.4 8.5 1.2 1 0 0 1 1 1 0 PIN like domain Spc7 PF08317.11 KXT01528.1 - 0.23 10.3 14.9 0.5 9.2 10.4 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Presenilin PF01080.17 KXT01528.1 - 0.27 10.0 4.2 0.33 9.7 4.2 1.1 1 0 0 1 1 1 0 Presenilin Atg14 PF10186.9 KXT01528.1 - 0.29 10.2 15.5 0.51 9.4 15.5 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 V_ATPase_I PF01496.19 KXT01528.1 - 0.34 8.8 8.5 0.43 8.5 8.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DDE_Tnp_ISL3 PF01610.17 KXT01528.1 - 0.43 10.3 8.2 0.66 9.6 8.2 1.2 1 0 0 1 1 1 0 Transposase DUF1664 PF07889.12 KXT01528.1 - 2.5 8.2 9.2 12 6.0 3.1 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) YabA PF06156.13 KXT01528.1 - 2.9 8.6 13.3 6.6 7.4 1.7 2.4 1 1 1 2 2 2 0 Initiation control protein YabA DUF4407 PF14362.6 KXT01528.1 - 3.7 6.8 14.1 5.8 6.2 14.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FapA PF03961.13 KXT01528.1 - 3.7 6.1 10.7 6.9 5.2 10.7 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A TMPIT PF07851.13 KXT01528.1 - 4 6.6 11.9 6 6.0 11.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein RasGAP_C PF03836.15 KXT01528.1 - 8.8 6.5 14.6 1.3 9.2 6.6 2.5 2 1 1 3 3 2 0 RasGAP C-terminus RNase_PH PF01138.21 KXT01529.1 - 6.2e-12 46.1 0.0 1.2e-11 45.3 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 tRNA_anti-codon PF01336.25 KXT01530.1 - 0.0038 17.2 0.0 0.016 15.2 0.0 2.0 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain REPA_OB_2 PF16900.5 KXT01530.1 - 0.025 14.5 0.1 0.058 13.3 0.1 1.5 1 0 0 1 1 1 0 Replication protein A OB domain zf_C2HC_14 PF18574.1 KXT01530.1 - 0.11 12.3 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 C2HC Zing finger domain MBA1 PF07961.11 KXT01530.1 - 0.26 10.3 0.0 0.4 9.7 0.0 1.2 1 0 0 1 1 1 0 MBA1-like protein Rrn6 PF10214.9 KXT01531.1 - 9.7e-136 454.5 8.8 1.2e-135 454.2 8.8 1.1 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Phage_min_cap2 PF06152.11 KXT01531.1 - 0.27 10.1 4.7 0.42 9.5 4.7 1.2 1 0 0 1 1 1 0 Phage minor capsid protein 2 NARP1 PF12569.8 KXT01531.1 - 1.5 7.6 5.5 2.6 6.9 5.5 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 UPF0029 PF01205.19 KXT01532.1 - 4e-21 75.3 0.1 8.9e-21 74.2 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 ESSS PF10183.9 KXT01533.1 - 6.9e-17 61.6 0.0 7.9e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF3961 PF13106.6 KXT01533.1 - 0.14 11.8 3.3 0.24 11.0 3.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3961) MFS_1 PF07690.16 KXT01534.1 - 4.9e-31 107.9 57.2 8.8e-27 93.9 37.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXT01534.1 - 2.2e-14 53.2 26.4 1.3e-13 50.6 26.4 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXT01535.1 - 4.9e-31 107.9 57.2 8.8e-27 93.9 37.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXT01535.1 - 2.2e-14 53.2 26.4 1.3e-13 50.6 26.4 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter WH1 PF00568.23 KXT01536.1 - 1.9e-29 101.8 0.3 2.6e-29 101.4 0.3 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.20 KXT01536.1 - 2.6e-06 27.1 0.3 5.7e-06 26.0 0.3 1.5 1 0 0 1 1 1 1 WH2 motif DCP1 PF06058.13 KXT01536.1 - 0.036 14.0 0.1 0.056 13.4 0.1 1.3 1 0 0 1 1 1 0 Dcp1-like decapping family KH_1 PF00013.29 KXT01537.1 - 0.11 12.4 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 KH domain M20_dimer PF07687.14 KXT01538.1 - 9.2e-07 28.8 0.1 1.8e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KXT01538.1 - 9.4e-07 28.7 0.1 1.5e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KXT01539.1 - 9.2e-07 28.8 0.1 1.8e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KXT01539.1 - 9.4e-07 28.7 0.1 1.5e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 PIF1 PF05970.14 KXT01540.1 - 6.6e-62 209.8 0.0 8.3e-49 166.7 0.1 2.6 2 1 1 3 3 3 2 PIF1-like helicase AAA_30 PF13604.6 KXT01540.1 - 2.4e-23 82.9 0.0 4.4e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXT01540.1 - 4.4e-12 46.6 0.0 1e-11 45.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KXT01540.1 - 3.6e-08 33.8 0.0 1e-07 32.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KXT01540.1 - 5.1e-06 26.1 0.0 1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region Herpes_Helicase PF02689.14 KXT01540.1 - 0.00018 19.6 0.0 0.00068 17.7 0.0 1.8 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.6 KXT01540.1 - 0.00028 20.7 0.0 0.0006 19.6 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA PF00004.29 KXT01540.1 - 0.0012 19.2 0.0 0.0029 18.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXT01540.1 - 0.0014 19.0 0.1 0.0039 17.6 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 KXT01540.1 - 0.0057 15.8 0.0 0.0097 15.0 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein PhoH PF02562.16 KXT01540.1 - 0.0078 15.7 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein RNA_helicase PF00910.22 KXT01540.1 - 0.0084 16.5 0.0 0.021 15.2 0.0 1.8 1 0 0 1 1 1 1 RNA helicase NACHT PF05729.12 KXT01540.1 - 0.0097 15.8 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain DUF2075 PF09848.9 KXT01540.1 - 0.011 15.0 0.1 0.011 15.0 0.1 2.1 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.22 KXT01540.1 - 0.012 14.8 0.1 0.022 13.9 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain ResIII PF04851.15 KXT01540.1 - 0.014 15.4 0.3 0.059 13.4 0.1 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit ATPase_2 PF01637.18 KXT01540.1 - 0.014 15.3 0.0 0.13 12.2 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 KXT01540.1 - 0.014 15.4 0.5 0.16 12.0 0.5 2.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TrwB_AAD_bind PF10412.9 KXT01540.1 - 0.015 14.2 0.0 0.027 13.4 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_11 PF13086.6 KXT01540.1 - 0.017 14.9 0.0 0.017 14.9 0.0 3.1 2 1 1 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 KXT01540.1 - 0.023 14.6 0.1 0.048 13.6 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase DUF5605 PF18310.1 KXT01540.1 - 0.062 13.2 0.0 0.19 11.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5605) AAA_14 PF13173.6 KXT01540.1 - 0.078 13.0 0.1 0.39 10.8 0.1 2.1 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KXT01540.1 - 0.079 13.1 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 KXT01540.1 - 0.086 13.4 0.5 0.4 11.2 0.0 2.4 2 0 0 2 2 2 0 ABC transporter Mg_chelatase PF01078.21 KXT01540.1 - 0.1 12.0 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KXT01540.1 - 0.15 11.7 0.1 0.36 10.5 0.1 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain WD40 PF00400.32 KXT01541.1 - 2.3e-09 37.7 14.8 0.00014 22.6 0.1 5.3 5 1 0 5 5 5 3 WD domain, G-beta repeat PQQ_3 PF13570.6 KXT01541.1 - 3.2e-05 24.3 0.7 0.34 11.5 0.3 4.1 4 0 0 4 4 4 1 PQQ-like domain ANAPC4_WD40 PF12894.7 KXT01541.1 - 0.0003 21.0 0.2 11 6.4 0.0 3.8 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXT01541.1 - 0.00074 18.3 2.1 0.1 11.2 0.0 2.9 1 1 2 3 3 3 2 Nucleoporin Nup120/160 PQQ_2 PF13360.6 KXT01541.1 - 0.0044 16.6 2.1 1.6 8.2 0.0 3.0 2 2 0 2 2 2 2 PQQ-like domain Nucleoporin_N PF08801.11 KXT01541.1 - 0.024 13.4 0.0 0.053 12.3 0.0 1.6 1 0 0 1 1 1 0 Nup133 N terminal like APG6_N PF17675.1 KXT01541.1 - 0.05 14.1 2.7 0.082 13.4 2.7 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region HPS3_N PF14761.6 KXT01541.1 - 0.092 12.3 1.0 0.95 9.0 0.0 2.2 1 1 1 2 2 2 0 Hermansky-Pudlak syndrome 3 TRAM_LAG1_CLN8 PF03798.16 KXT01542.1 - 4.5e-37 127.7 18.4 4.5e-37 127.7 18.4 2.0 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KXT01542.1 - 1.2e-23 82.6 0.0 1.2e-23 82.6 0.0 1.9 2 0 0 2 2 2 1 TRAM1-like protein WD40 PF00400.32 KXT01543.1 - 4.3e-26 90.7 4.0 9.6e-07 29.4 0.1 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXT01543.1 - 2.1e-05 24.7 0.0 1.1 9.6 0.0 4.0 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXT01543.1 - 0.0032 16.5 0.0 0.077 11.9 0.0 2.8 4 0 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein adh_short PF00106.25 KXT01544.1 - 6e-32 110.7 0.3 7.9e-32 110.3 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT01544.1 - 1.1e-25 90.6 0.0 1.4e-25 90.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT01544.1 - 1.3e-09 38.2 0.3 2.3e-09 37.4 0.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXT01544.1 - 0.043 13.3 0.1 0.1 12.0 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family RabGAP-TBC PF00566.18 KXT01545.1 - 8.7e-39 133.4 2.4 3.2e-38 131.5 2.4 1.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 KXT01545.1 - 7.7e-08 32.0 0.0 5.5e-06 26.0 0.2 2.9 2 1 0 2 2 2 1 Rab-binding domain (RBD) Pkinase PF00069.25 KXT01546.1 - 2.5e-51 174.6 0.0 3.4e-51 174.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT01546.1 - 1.1e-30 106.8 0.0 1.6e-30 106.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXT01546.1 - 2.1e-10 40.4 0.0 2.6e-07 30.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KXT01546.1 - 0.0048 16.8 0.0 0.009 16.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KXT01546.1 - 0.014 14.7 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF918 PF06033.11 KXT01546.1 - 0.13 12.3 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF918) TrmE_N PF10396.9 KXT01547.1 - 2e-36 124.8 0.0 8.3e-36 122.8 0.0 2.1 2 0 0 2 2 2 1 GTP-binding protein TrmE N-terminus MnmE_helical PF12631.7 KXT01547.1 - 6.8e-33 114.6 0.0 2.4e-32 112.8 0.0 1.9 1 1 0 1 1 1 1 MnmE helical domain MMR_HSR1 PF01926.23 KXT01547.1 - 7.8e-20 71.1 0.0 1.3e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KXT01547.1 - 8.1e-07 29.2 0.0 2.5e-06 27.6 0.0 1.8 1 1 0 1 1 1 1 Dynamin family FeoB_N PF02421.18 KXT01547.1 - 3.4e-06 26.7 0.3 4.4e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KXT01547.1 - 5.9e-05 23.0 0.9 0.35 10.8 0.6 2.6 2 1 0 2 2 2 2 RsgA GTPase Glyco_hydro_3_C PF01915.22 KXT01547.1 - 0.003 17.5 0.1 0.0048 16.9 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain GTP_EFTU PF00009.27 KXT01547.1 - 0.007 15.9 0.0 0.6 9.6 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain cobW PF02492.19 KXT01547.1 - 0.013 15.1 0.4 0.099 12.2 0.4 2.1 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Ras PF00071.22 KXT01547.1 - 0.072 12.7 0.2 4.2 6.9 0.1 2.4 2 0 0 2 2 2 0 Ras family Roc PF08477.13 KXT01547.1 - 0.074 13.3 0.1 1.1 9.6 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXT01547.1 - 0.14 11.6 0.1 16 4.9 0.1 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family SH3_1 PF00018.28 KXT01548.1 - 4.5e-05 23.0 0.0 8.1e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXT01548.1 - 0.061 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain TauD PF02668.16 KXT01549.1 - 5e-47 161.0 0.5 7.7e-47 160.3 0.5 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family F_bP_aldolase PF01116.20 KXT01549.1 - 0.064 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-II Lipase_GDSL_2 PF13472.6 KXT01550.1 - 3.8e-18 66.5 0.3 5.6e-18 66.0 0.3 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXT01550.1 - 3e-07 30.6 0.0 5.5e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Fes1 PF08609.10 KXT01552.1 - 1.4e-27 96.4 2.6 1.4e-27 96.4 2.6 2.0 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 WW PF00397.26 KXT01552.1 - 1.9e-10 40.6 6.4 3.9e-10 39.6 6.4 1.6 1 0 0 1 1 1 1 WW domain HEAT_2 PF13646.6 KXT01552.1 - 4.4e-06 27.0 0.1 1e-05 25.8 0.1 1.6 1 0 0 1 1 1 1 HEAT repeats HEAT PF02985.22 KXT01552.1 - 0.00044 20.3 0.1 0.35 11.3 0.0 2.6 2 0 0 2 2 2 2 HEAT repeat Arm PF00514.23 KXT01552.1 - 0.00061 19.7 0.1 0.53 10.4 0.0 2.6 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KXT01552.1 - 0.0061 17.1 0.1 0.032 14.8 0.1 2.3 1 1 1 2 2 2 1 HEAT-like repeat Cnd1 PF12717.7 KXT01552.1 - 0.0099 15.9 0.0 0.017 15.2 0.0 1.3 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Glyco_hydro_67M PF07488.12 KXT01552.1 - 0.069 12.2 0.1 0.1 11.6 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 middle domain DUF2142 PF09913.9 KXT01553.1 - 0.081 11.8 5.1 0.13 11.1 5.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) Glyco_hydro_16 PF00722.21 KXT01555.1 - 1e-33 116.3 2.1 1e-33 116.3 2.1 2.0 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 SOG2 PF10428.9 KXT01555.1 - 4.4 6.4 29.2 7 5.7 29.2 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Actin PF00022.19 KXT01556.1 - 3.3e-144 480.5 0.0 1.3e-143 478.5 0.0 1.7 1 1 0 1 1 1 1 Actin DAO PF01266.24 KXT01557.1 - 2.5e-62 211.5 0.8 2.9e-62 211.3 0.8 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXT01557.1 - 4.5e-07 29.4 0.1 0.0036 16.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXT01557.1 - 1.9e-06 28.3 0.4 0.0013 19.3 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXT01557.1 - 6e-06 26.4 0.2 1.3e-05 25.3 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain MCRA PF06100.11 KXT01557.1 - 3.8e-05 22.7 0.1 0.00046 19.1 0.1 2.0 2 0 0 2 2 2 1 MCRA family FAD_binding_2 PF00890.24 KXT01557.1 - 0.00047 19.4 1.3 0.0023 17.1 1.3 2.0 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 KXT01557.1 - 0.00068 19.0 0.0 0.0013 18.2 0.0 1.4 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 KXT01557.1 - 0.0029 16.5 0.6 0.0094 14.8 0.1 1.8 2 0 0 2 2 2 1 Tryptophan halogenase FAD_binding_3 PF01494.19 KXT01557.1 - 0.028 13.7 0.0 0.88 8.8 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 KXT01557.1 - 0.035 13.3 0.3 0.054 12.7 0.3 1.2 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 KXT01557.1 - 0.063 13.3 0.3 0.25 11.3 0.1 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Mqo PF06039.15 KXT01557.1 - 0.094 11.3 0.0 9.6 4.6 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) FAD_oxidored PF12831.7 KXT01557.1 - 0.13 11.5 0.4 3 7.1 0.4 2.1 1 1 0 1 1 1 0 FAD dependent oxidoreductase Arylsulfotran_2 PF14269.6 KXT01558.1 - 5.4e-70 236.1 0.1 7.2e-70 235.7 0.1 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KXT01558.1 - 3.2e-10 39.5 0.1 7.6e-09 35.0 0.1 2.3 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) POT1PC PF16686.5 KXT01558.1 - 0.037 13.9 0.1 0.23 11.3 0.0 2.0 2 0 0 2 2 2 0 ssDNA-binding domain of telomere protection protein Bystin PF05291.11 KXT01559.1 - 4.4e-125 416.8 0.0 7e-125 416.1 0.0 1.2 1 0 0 1 1 1 1 Bystin Ribonuc_red_sm PF00268.21 KXT01559.1 - 7.7e-121 402.8 2.7 1.2e-120 402.2 2.7 1.3 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain zf-C3HC4_3 PF13920.6 KXT01561.1 - 3.2e-09 36.5 9.2 4.8e-09 35.9 9.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXT01561.1 - 1.8e-07 31.1 4.3 1.8e-07 31.0 2.2 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KXT01561.1 - 2.1e-07 31.2 9.1 3.3e-07 30.5 9.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KXT01561.1 - 8.6e-07 28.8 10.8 1.4e-06 28.1 10.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KXT01561.1 - 1.4e-05 24.8 10.1 2.4e-05 24.1 10.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXT01561.1 - 2.1e-05 24.3 8.5 4.1e-05 23.4 8.5 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KXT01561.1 - 2.6e-05 24.0 12.2 0.00021 21.1 12.7 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KXT01561.1 - 0.0041 17.3 7.8 0.0081 16.3 7.8 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KXT01561.1 - 0.013 15.8 5.7 0.025 14.8 5.7 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain Rad50_zn_hook PF04423.14 KXT01561.1 - 0.052 13.4 0.2 0.12 12.2 0.2 1.6 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-RING_4 PF14570.6 KXT01561.1 - 0.074 12.8 5.7 0.18 11.6 5.7 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 KXT01561.1 - 0.24 11.6 8.1 0.52 10.5 8.1 1.6 1 1 0 1 1 1 0 FANCL C-terminal domain zf-HC5HC2H PF13771.6 KXT01561.1 - 0.77 10.0 9.2 1.9 8.8 9.3 1.6 1 1 0 1 1 1 0 PHD-like zinc-binding domain Macoilin PF09726.9 KXT01561.1 - 2.3 6.7 5.3 3 6.3 5.3 1.1 1 0 0 1 1 1 0 Macoilin family DAP_B PF07930.12 KXT01562.1 - 1.2e-71 240.5 0.0 1.6e-71 240.0 0.0 1.2 1 0 0 1 1 1 1 D-aminopeptidase, domain B Beta-lactamase PF00144.24 KXT01562.1 - 5.7e-38 131.0 0.1 9.5e-38 130.3 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase Transcrip_reg PF01709.20 KXT01563.1 - 5.8e-69 232.1 1.3 6.7e-69 232.0 1.3 1.0 1 0 0 1 1 1 1 Transcriptional regulator FH2 PF02181.23 KXT01564.1 - 1.8e-88 297.2 5.3 1.8e-88 297.2 5.3 2.1 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 KXT01564.1 - 1.1e-64 217.5 1.9 1.1e-64 217.4 0.2 2.0 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 KXT01564.1 - 1.8e-50 171.3 0.3 1.8e-50 171.3 0.3 3.4 3 1 1 4 4 4 2 Diaphanous FH3 Domain PcfK PF14058.6 KXT01564.1 - 0.13 12.5 1.0 0.41 10.9 1.0 1.8 1 0 0 1 1 1 0 PcfK-like protein SlyX PF04102.12 KXT01564.1 - 2.1 9.0 11.6 26 5.5 4.8 4.4 3 0 0 3 3 3 0 SlyX AA_permease_2 PF13520.6 KXT01565.1 - 6.1e-47 160.4 49.4 7.9e-47 160.0 49.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXT01565.1 - 5.5e-19 68.1 38.9 7.9e-19 67.6 38.9 1.1 1 0 0 1 1 1 1 Amino acid permease Phage_holin_3_6 PF07332.11 KXT01565.1 - 9.5 6.3 19.1 0.45 10.6 0.2 4.2 4 0 0 4 4 4 0 Putative Actinobacterial Holin-X, holin superfamily III LSM PF01423.22 KXT01566.1 - 1.6e-18 66.2 0.2 2.4e-18 65.6 0.2 1.3 1 0 0 1 1 1 1 LSM domain LSM PF01423.22 KXT01567.1 - 1.6e-18 66.2 0.2 2.4e-18 65.6 0.2 1.3 1 0 0 1 1 1 1 LSM domain DUF3246 PF11596.8 KXT01568.1 - 0.00048 19.6 3.5 0.00057 19.4 3.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3246) BRCT PF00533.26 KXT01568.1 - 0.005 17.2 0.1 0.017 15.5 0.0 1.9 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain DUF2052 PF09747.9 KXT01568.1 - 0.0071 16.5 3.7 0.0099 16.0 3.7 1.1 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) CDC45 PF02724.14 KXT01568.1 - 0.045 12.1 1.1 0.046 12.0 1.1 1.1 1 0 0 1 1 1 0 CDC45-like protein MPM1 PF17234.2 KXT01568.1 - 0.05 13.9 1.3 0.093 13.0 0.9 1.6 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 PBP1_TM PF14812.6 KXT01568.1 - 0.051 14.0 6.7 0.089 13.2 6.7 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF5427 PF10310.9 KXT01568.1 - 0.08 11.9 5.4 0.092 11.7 5.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) BRCT_2 PF16589.5 KXT01568.1 - 0.14 12.5 0.0 0.36 11.3 0.0 1.7 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain TLP-20 PF06088.11 KXT01568.1 - 0.37 10.7 3.8 0.6 10.0 3.8 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) RR_TM4-6 PF06459.12 KXT01568.1 - 0.57 10.0 5.1 0.75 9.6 5.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM176 PF14851.6 KXT01568.1 - 2.1 8.0 5.2 3.4 7.3 5.2 1.4 1 0 0 1 1 1 0 FAM176 family DUF3246 PF11596.8 KXT01569.1 - 0.00048 19.6 3.5 0.00057 19.4 3.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3246) BRCT PF00533.26 KXT01569.1 - 0.005 17.2 0.1 0.017 15.5 0.0 1.9 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain DUF2052 PF09747.9 KXT01569.1 - 0.0071 16.5 3.7 0.0099 16.0 3.7 1.1 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) CDC45 PF02724.14 KXT01569.1 - 0.045 12.1 1.1 0.046 12.0 1.1 1.1 1 0 0 1 1 1 0 CDC45-like protein MPM1 PF17234.2 KXT01569.1 - 0.05 13.9 1.3 0.093 13.0 0.9 1.6 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 PBP1_TM PF14812.6 KXT01569.1 - 0.051 14.0 6.7 0.089 13.2 6.7 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF5427 PF10310.9 KXT01569.1 - 0.08 11.9 5.4 0.092 11.7 5.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) BRCT_2 PF16589.5 KXT01569.1 - 0.14 12.5 0.0 0.36 11.3 0.0 1.7 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain TLP-20 PF06088.11 KXT01569.1 - 0.37 10.7 3.8 0.6 10.0 3.8 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) RR_TM4-6 PF06459.12 KXT01569.1 - 0.57 10.0 5.1 0.75 9.6 5.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM176 PF14851.6 KXT01569.1 - 2.1 8.0 5.2 3.4 7.3 5.2 1.4 1 0 0 1 1 1 0 FAM176 family HAD_2 PF13419.6 KXT01570.1 - 7.4e-06 26.2 0.0 0.00067 19.8 0.0 2.4 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXT01570.1 - 8.6e-06 26.2 0.0 0.24 11.7 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXT01570.1 - 9.8e-05 22.3 0.0 0.00047 20.2 0.0 2.1 2 0 0 2 2 2 1 HAD-hyrolase-like RNA_pol_Rpc4 PF05132.14 KXT01570.1 - 3 8.3 6.3 3.6 8.0 4.4 2.1 2 1 0 2 2 2 0 RNA polymerase III RPC4 HAD_2 PF13419.6 KXT01572.1 - 7.4e-06 26.2 0.0 0.00067 19.8 0.0 2.4 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXT01572.1 - 8.6e-06 26.2 0.0 0.24 11.7 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXT01572.1 - 9.8e-05 22.3 0.0 0.00047 20.2 0.0 2.1 2 0 0 2 2 2 1 HAD-hyrolase-like RNA_pol_Rpc4 PF05132.14 KXT01572.1 - 3 8.3 6.3 3.6 8.0 4.4 2.1 2 1 0 2 2 2 0 RNA polymerase III RPC4 p450 PF00067.22 KXT01573.1 - 1e-58 199.2 0.0 1.4e-58 198.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 KXT01574.1 - 1.9e-12 46.8 33.5 3.1e-07 29.7 21.3 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 KXT01574.1 - 7.1e-07 29.1 4.3 2.5e-06 27.3 4.3 1.9 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 DUF3487 PF11990.8 KXT01574.1 - 0.085 12.7 0.3 0.65 9.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) DUF2561 PF10812.8 KXT01574.1 - 0.4 10.7 2.7 0.26 11.3 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2561) Thioredoxin PF00085.20 KXT01576.1 - 4.3e-24 84.5 0.0 8e-24 83.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Transglut_core PF01841.19 KXT01576.1 - 5.3e-13 49.4 0.1 1.7e-12 47.8 0.0 1.9 2 0 0 2 2 2 1 Transglutaminase-like superfamily OST3_OST6 PF04756.13 KXT01576.1 - 2.8e-05 23.6 0.0 5.6e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 KXT01576.1 - 7.4e-05 23.0 0.0 0.0018 18.6 0.0 2.4 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.6 KXT01576.1 - 0.00065 20.1 0.1 0.0024 18.3 0.0 1.9 2 1 0 2 2 2 1 Thioredoxin-like domain DUF553 PF04473.12 KXT01576.1 - 0.0086 15.6 0.0 0.23 11.0 0.0 2.4 1 1 0 1 1 1 1 Transglutaminase-like domain AhpC-TSA PF00578.21 KXT01576.1 - 0.13 12.2 0.0 0.5 10.3 0.0 1.8 1 1 0 1 1 1 0 AhpC/TSA family CorA PF01544.18 KXT01577.1 - 4.6e-24 85.2 13.8 4e-20 72.3 2.6 3.5 4 0 0 4 4 4 3 CorA-like Mg2+ transporter protein ATP13 PF12921.7 KXT01577.1 - 1.2e-23 83.1 0.0 2.8e-23 82.0 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial ATPase expression PPR_3 PF13812.6 KXT01577.1 - 0.00046 20.2 0.0 0.25 11.4 0.0 2.9 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR_2 PF13041.6 KXT01577.1 - 0.0025 18.0 0.2 0.015 15.4 0.0 2.4 2 0 0 2 2 2 1 PPR repeat family PPR PF01535.20 KXT01577.1 - 0.024 14.9 0.2 0.77 10.1 0.0 3.1 3 0 0 3 3 3 0 PPR repeat SUR7 PF06687.12 KXT01577.1 - 0.91 9.1 5.0 1.5 8.4 5.0 1.3 1 0 0 1 1 1 0 SUR7/PalI family F-box-like PF12937.7 KXT01578.1 - 0.0022 17.9 0.1 0.0055 16.6 0.1 1.7 1 0 0 1 1 1 1 F-box-like Polysacc_deac_1 PF01522.21 KXT01579.1 - 1.9e-12 47.2 0.0 3.5e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase NIF PF03031.18 KXT01580.1 - 6e-25 87.8 0.1 1.1e-24 87.0 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase AF-4 PF05110.13 KXT01580.1 - 0.079 11.0 9.2 0.1 10.6 9.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Polysacc_deac_1 PF01522.21 KXT01581.1 - 1.9e-12 47.2 0.0 3.5e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Polysacc_deac_1 PF01522.21 KXT01582.1 - 1.9e-12 47.2 0.0 3.5e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DNApol_Exo PF18136.1 KXT01583.1 - 1.5e-101 339.3 0.0 2.4e-101 338.6 0.0 1.3 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 KXT01583.1 - 5.1e-57 193.6 0.0 7.6e-57 193.1 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.20 KXT01583.1 - 0.14 11.9 0.0 1.8 8.2 0.0 2.5 2 0 0 2 2 2 0 3'-5' exonuclease Spo7 PF03907.13 KXT01584.1 - 1.6e-85 286.1 0.2 3.2e-85 285.1 0.0 1.5 2 0 0 2 2 2 1 Spo7-like protein FA_hydroxylase PF04116.13 KXT01585.1 - 9.3e-21 74.6 8.7 9.3e-21 74.6 8.7 2.2 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily 7TM_GPCR_Srz PF10325.9 KXT01585.1 - 0.4 10.0 3.8 0.99 8.7 0.3 2.2 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srz PIN_8 PF18476.1 KXT01586.1 - 2.4 7.9 29.4 0.21 11.4 10.1 2.7 1 1 1 2 2 2 0 PIN like domain Abhydrolase_6 PF12697.7 KXT01588.1 - 0.00045 20.9 0.2 0.0028 18.3 0.1 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KXT01588.1 - 0.026 14.0 0.0 0.046 13.2 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Esterase_phd PF10503.9 KXT01588.1 - 0.074 12.5 0.1 0.3 10.5 0.1 1.9 1 1 0 1 1 1 0 Esterase PHB depolymerase Abhydrolase_6 PF12697.7 KXT01589.1 - 0.00045 20.9 0.2 0.0028 18.3 0.1 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KXT01589.1 - 0.026 14.0 0.0 0.046 13.2 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Esterase_phd PF10503.9 KXT01589.1 - 0.074 12.5 0.1 0.3 10.5 0.1 1.9 1 1 0 1 1 1 0 Esterase PHB depolymerase Abhydrolase_1 PF00561.20 KXT01590.1 - 6.8e-25 88.2 0.1 1.7e-24 86.9 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KXT01590.1 - 7.2e-18 64.6 0.1 1.9e-17 63.3 0.1 1.7 1 0 0 1 1 1 1 TAP-like protein Ser_hydrolase PF06821.13 KXT01590.1 - 0.038 13.9 0.0 0.068 13.0 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Abhydrolase_1 PF00561.20 KXT01591.1 - 6.8e-25 88.2 0.1 1.7e-24 86.9 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KXT01591.1 - 7.2e-18 64.6 0.1 1.9e-17 63.3 0.1 1.7 1 0 0 1 1 1 1 TAP-like protein Ser_hydrolase PF06821.13 KXT01591.1 - 0.038 13.9 0.0 0.068 13.0 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Abhydrolase_1 PF00561.20 KXT01592.1 - 5.2e-21 75.5 0.0 1.3e-18 67.6 0.0 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXT01592.1 - 4.2e-17 63.5 0.8 4.2e-17 63.5 0.8 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXT01592.1 - 8.5e-16 57.9 0.0 1.2e-14 54.2 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF915 PF06028.11 KXT01592.1 - 1.6e-06 27.6 0.0 3.1e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.20 KXT01592.1 - 1.7e-06 27.9 0.0 3.4e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.13 KXT01592.1 - 0.01 15.6 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_2 PF02230.16 KXT01592.1 - 0.025 14.4 0.0 0.3 10.9 0.0 2.4 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase DUF900 PF05990.12 KXT01592.1 - 0.045 13.3 0.0 0.083 12.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) LIDHydrolase PF10230.9 KXT01592.1 - 0.06 12.9 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DUF2048 PF09752.9 KXT01592.1 - 0.13 11.4 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Abhydrolase domain containing 18 Chlorophyllase2 PF12740.7 KXT01592.1 - 0.16 10.9 0.0 0.28 10.1 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Lipase_3 PF01764.25 KXT01592.1 - 0.19 11.6 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) SPRY PF00622.28 KXT01594.1 - 0.0079 16.3 0.0 0.41 10.8 0.0 3.0 2 1 1 3 3 3 1 SPRY domain ABC_tran_CTD PF16326.5 KXT01594.1 - 0.02 15.1 1.2 0.02 15.1 1.2 2.4 1 1 1 2 2 2 0 ABC transporter C-terminal domain XhlA PF10779.9 KXT01594.1 - 0.055 13.7 9.0 0.17 12.1 0.4 3.3 3 0 0 3 3 3 0 Haemolysin XhlA EzrA PF06160.12 KXT01594.1 - 0.095 10.9 6.2 0.14 10.3 6.2 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Het-C PF07217.11 KXT01594.1 - 0.17 10.4 3.5 0.25 9.8 3.5 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C TMF_TATA_bd PF12325.8 KXT01594.1 - 0.18 12.0 11.3 0.16 12.2 1.6 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Fmp27_WPPW PF10359.9 KXT01594.1 - 0.23 10.3 5.6 0.44 9.3 5.6 1.4 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Flagellin_N PF00669.20 KXT01594.1 - 0.27 11.3 3.6 0.63 10.1 1.2 2.5 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region FlaC_arch PF05377.11 KXT01594.1 - 1 9.8 6.1 7 7.1 0.1 3.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Spc7 PF08317.11 KXT01594.1 - 2.1 7.2 13.2 14 4.4 11.0 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Snapin_Pallidin PF14712.6 KXT01594.1 - 2.3 8.7 6.1 1.1 9.7 3.3 2.0 2 0 0 2 2 1 0 Snapin/Pallidin DUF2802 PF10975.8 KXT01594.1 - 2.9 8.1 5.9 16 5.7 0.1 2.9 3 0 0 3 3 2 0 Protein of unknown function (DUF2802) Phage_GP20 PF06810.11 KXT01594.1 - 3.7 7.3 9.1 2.3 8.0 1.3 3.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF16 PF01519.16 KXT01594.1 - 4.1 7.9 6.7 2.4 8.7 2.4 2.6 1 1 1 2 2 2 0 Protein of unknown function DUF16 SH3_1 PF00018.28 KXT01597.1 - 5.7e-22 77.1 0.0 1.9e-10 40.2 0.0 2.6 2 0 0 2 2 2 2 SH3 domain SAC3_GANP PF03399.16 KXT01597.1 - 4.4e-21 75.5 2.3 9.7e-20 71.1 2.3 2.2 1 1 0 1 1 1 1 SAC3/GANP family PX PF00787.24 KXT01597.1 - 1.2e-13 51.0 0.0 5.6e-13 48.9 0.0 2.2 1 0 0 1 1 1 1 PX domain SH3_9 PF14604.6 KXT01597.1 - 6.1e-13 48.4 0.1 8e-06 25.6 0.1 2.7 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 KXT01597.1 - 2.2e-08 33.6 0.0 2e-05 24.2 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain CSN8_PSD8_EIF3K PF10075.9 KXT01597.1 - 9.8e-08 32.1 0.2 2.5e-07 30.8 0.2 1.6 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family TMEM51 PF15345.6 KXT01597.1 - 8.1 6.2 9.3 9.1 6.0 0.1 2.5 2 0 0 2 2 2 0 Transmembrane protein 51 DUF423 PF04241.15 KXT01598.1 - 4e-25 87.8 2.6 5.6e-25 87.4 2.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF423) Topoisom_I PF01028.20 KXT01599.1 - 2e-96 321.7 6.0 2e-96 321.7 6.0 2.3 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 KXT01599.1 - 1.1e-95 319.2 6.6 1.1e-95 319.2 6.6 3.9 5 0 0 5 5 5 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 KXT01599.1 - 9.7e-34 115.1 0.6 3.8e-33 113.2 0.6 2.2 1 0 0 1 1 1 1 C-terminal topoisomerase domain LptF_LptG PF03739.14 KXT01599.1 - 0.2 10.5 1.6 0.36 9.6 1.6 1.4 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG DLH PF01738.18 KXT01601.1 - 4.1e-30 104.9 0.1 5e-30 104.7 0.1 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF915 PF06028.11 KXT01601.1 - 0.016 14.6 0.0 0.067 12.5 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DLH PF01738.18 KXT01602.1 - 4.1e-30 104.9 0.1 5e-30 104.7 0.1 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF915 PF06028.11 KXT01602.1 - 0.016 14.6 0.0 0.067 12.5 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Fungal_trans PF04082.18 KXT01603.1 - 1.8e-17 63.3 0.0 3.4e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT01603.1 - 1.2e-08 34.9 11.5 2.4e-08 34.0 11.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSP70 PF00012.20 KXT01604.1 - 4.5e-264 877.2 14.0 5.2e-264 877.0 14.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KXT01604.1 - 3.6e-12 45.7 2.8 9.8e-11 41.0 0.9 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 KXT01604.1 - 0.0014 18.4 0.0 0.0032 17.2 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain HXXSHH PF07586.11 KXT01604.1 - 0.0064 16.1 3.5 0.011 15.3 3.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1552) DUF4363 PF14276.6 KXT01604.1 - 0.011 15.8 4.6 0.024 14.7 4.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) Syntaxin-18_N PF10496.9 KXT01604.1 - 0.072 13.3 0.0 0.31 11.3 0.0 2.2 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus SMBP PF16785.5 KXT01604.1 - 0.2 11.9 8.3 0.082 13.1 5.4 1.9 2 0 0 2 2 2 0 Small metal-binding protein FtsA PF14450.6 KXT01604.1 - 0.49 10.8 10.7 1.8 9.0 0.1 4.1 3 2 0 3 3 3 0 Cell division protein FtsA Choline_transpo PF04515.12 KXT01605.1 - 5.8e-82 275.5 22.5 5.8e-82 275.5 22.5 2.5 2 1 0 2 2 2 1 Plasma-membrane choline transporter DUF973 PF06157.11 KXT01605.1 - 0.81 8.7 13.5 0.052 12.6 7.5 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF973) Aldedh PF00171.22 KXT01606.1 - 1.3e-95 320.7 0.0 1.5e-95 320.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GTP_EFTU PF00009.27 KXT01608.1 - 4e-46 157.0 0.0 6.4e-46 156.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 KXT01608.1 - 1.3e-36 125.9 8.9 2.3e-36 125.1 8.9 1.4 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 KXT01608.1 - 3.5e-23 81.7 0.0 9.3e-23 80.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 KXT01608.1 - 7.7e-18 64.3 0.0 2.7e-17 62.6 0.0 2.0 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KXT01608.1 - 2.1e-10 40.8 1.1 3e-10 40.4 0.1 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KXT01608.1 - 8.1e-07 29.0 0.0 1.7e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KXT01608.1 - 4.3e-06 26.8 0.1 7.9e-06 25.9 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXT01608.1 - 0.0011 18.6 0.4 0.17 11.4 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B SRPRB PF09439.10 KXT01608.1 - 0.053 13.0 0.2 0.56 9.6 0.2 2.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit MOSC PF03473.17 KXT01609.1 - 1.3e-26 93.2 0.0 2e-26 92.6 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KXT01609.1 - 5.1e-15 55.4 0.0 1.1e-14 54.3 0.0 1.7 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain DAO PF01266.24 KXT01610.1 - 5.1e-31 108.5 0.0 6e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXT01610.1 - 3.4e-06 27.2 0.0 7.9e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXT01610.1 - 4.2e-06 26.2 0.0 0.0034 16.7 0.0 2.4 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KXT01610.1 - 0.00015 21.2 0.0 0.21 10.9 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KXT01610.1 - 0.0036 17.8 0.0 0.013 16.1 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXT01610.1 - 0.0091 15.3 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KXT01610.1 - 0.011 15.0 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.23 KXT01610.1 - 0.012 15.6 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_9 PF13454.6 KXT01610.1 - 0.013 15.5 0.1 0.1 12.6 0.0 2.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 KXT01610.1 - 0.027 14.9 0.0 0.053 14.0 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Trp_halogenase PF04820.14 KXT01610.1 - 0.028 13.3 0.1 1.7 7.4 0.0 2.7 3 0 0 3 3 3 0 Tryptophan halogenase Shikimate_DH PF01488.20 KXT01610.1 - 0.11 12.6 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Dioxygenase_C PF00775.21 KXT01611.1 - 2e-08 33.9 0.0 3.2e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase Sugar_tr PF00083.24 KXT01612.1 - 6e-119 397.9 18.9 7.7e-119 397.5 18.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter COesterase PF00135.28 KXT01612.1 - 9.6e-68 229.3 0.0 2.7e-67 227.8 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family MFS_1 PF07690.16 KXT01612.1 - 1.8e-17 63.3 30.1 1.8e-17 63.3 30.1 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily Abhydrolase_3 PF07859.13 KXT01612.1 - 3.6e-05 23.7 0.1 9.5e-05 22.3 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold BT1 PF03092.16 KXT01612.1 - 0.027 12.7 0.5 0.34 9.1 0.1 2.1 2 0 0 2 2 2 0 BT1 family DUF2207 PF09972.9 KXT01612.1 - 3.6 6.2 9.2 0.026 13.3 0.5 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) SnoaL_4 PF13577.6 KXT01613.1 - 9.2e-25 87.2 0.3 1.1e-24 87.0 0.3 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KXT01613.1 - 0.00023 21.5 0.3 0.00032 21.1 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) DUF3225 PF11533.8 KXT01613.1 - 0.0042 16.8 0.1 0.0057 16.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3225) SnoaL_2 PF12680.7 KXT01613.1 - 0.0051 17.4 0.4 0.0073 16.9 0.4 1.3 1 1 0 1 1 1 1 SnoaL-like domain Lumazine_bd_2 PF12893.7 KXT01613.1 - 0.0055 17.4 0.1 0.071 13.8 0.0 2.0 1 1 1 2 2 2 1 Putative lumazine-binding DUF2114 PF09887.9 KXT01613.1 - 0.082 11.4 0.0 0.1 11.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2114) Scytalone_dh PF02982.14 KXT01613.1 - 0.093 12.5 0.3 1.3 8.8 0.0 2.0 1 1 1 2 2 2 0 Scytalone dehydratase Sugar_tr PF00083.24 KXT01614.1 - 3.4e-83 280.0 20.3 3.4e-83 280.0 20.3 1.4 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 KXT01614.1 - 2.7e-17 62.7 27.4 2.7e-17 62.7 27.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily HSP70 PF00012.20 KXT01615.1 - 9.3e-210 697.8 6.1 1.4e-209 697.2 6.1 1.3 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KXT01615.1 - 7.9e-16 57.8 0.3 7.3e-15 54.6 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KXT01615.1 - 0.00014 21.7 0.0 0.00026 20.8 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DEK_C PF08766.11 KXT01616.1 - 0.16 11.9 0.1 0.39 10.7 0.1 1.6 1 0 0 1 1 1 0 DEK C terminal domain RPE65 PF03055.15 KXT01617.1 - 6e-93 312.5 0.0 7.1e-93 312.3 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein RPE65 PF03055.15 KXT01618.1 - 6e-93 312.5 0.0 7.1e-93 312.3 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein GLEYA PF10528.9 KXT01619.1 - 1.3e-23 83.2 1.6 4.3e-23 81.5 1.6 2.0 1 0 0 1 1 1 1 GLEYA domain PA14 PF07691.12 KXT01619.1 - 1.2e-06 28.4 0.0 2.9e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 PA14 domain FixQ PF05545.11 KXT01619.1 - 0.076 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ DUF2415 PF10313.9 KXT01620.1 - 1e-15 57.4 0.0 2.1e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) Lgl_C PF08596.10 KXT01620.1 - 0.0091 14.7 0.0 0.021 13.5 0.0 1.6 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.32 KXT01620.1 - 0.011 16.6 0.4 13 6.8 0.0 3.9 3 1 1 4 4 4 0 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXT01620.1 - 0.019 15.2 0.0 11 6.4 0.0 3.6 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain ANAPC1 PF12859.7 KXT01620.1 - 9.8 6.8 7.9 5.7 7.5 0.0 3.0 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 1 COPIIcoated_ERV PF07970.12 KXT01621.1 - 1.2e-85 286.9 0.0 1.9e-85 286.2 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KXT01621.1 - 1.9e-29 101.9 0.0 1.1e-28 99.4 0.0 2.1 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Sugar_tr PF00083.24 KXT01622.1 - 0.035 13.0 0.5 0.042 12.7 0.5 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter Sec20 PF03908.13 KXT01624.1 - 6.5e-17 61.2 1.0 6.5e-17 61.2 1.0 2.7 3 0 0 3 3 3 1 Sec20 DUF4051 PF13260.6 KXT01624.1 - 0.082 12.6 1.3 0.2 11.4 1.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) FapA PF03961.13 KXT01624.1 - 3.8 6.0 13.2 0.014 14.1 2.5 2.2 2 1 1 3 3 3 0 Flagellar Assembly Protein A MR_MLE_C PF13378.6 KXT01625.1 - 6.4e-57 192.6 0.0 9.6e-57 192.1 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KXT01625.1 - 0.0027 16.9 0.1 0.01 15.0 0.1 1.8 1 1 1 2 2 2 1 Methylaspartate ammonia-lyase C-terminus PepSY PF03413.19 KXT01625.1 - 0.045 14.3 0.9 0.15 12.7 0.5 2.1 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Chitin_synth_2 PF03142.15 KXT01626.1 - 3.3e-281 933.5 0.4 4.6e-281 933.0 0.0 1.4 2 0 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.6 KXT01626.1 - 5.3e-11 42.8 5.9 2.1e-10 40.9 5.9 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KXT01626.1 - 1.5e-10 41.4 0.0 3.4e-09 36.9 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KXT01626.1 - 0.0013 18.2 0.0 0.031 13.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KXT01626.1 - 0.0083 16.0 0.0 0.18 11.6 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 DUF2235 PF09994.9 KXT01627.1 - 1.5e-81 274.0 0.3 2.1e-81 273.5 0.3 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) NTS_2 PF15448.6 KXT01627.1 - 0.0026 18.1 1.4 0.013 15.8 0.3 2.5 2 0 0 2 2 2 1 N-terminal segments of P. falciparum erythrocyte membrane protein BAAT_C PF08840.11 KXT01627.1 - 0.022 14.7 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Metallophos PF00149.28 KXT01630.1 - 4.3e-09 37.2 0.5 5.8e-07 30.2 0.5 2.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase RraA-like PF03737.15 KXT01631.1 - 2.3e-35 122.0 0.0 2.8e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 Aldolase/RraA UPRTase PF14681.6 KXT01632.1 - 2.9e-36 124.9 0.1 5.3e-36 124.0 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase HAD PF12710.7 KXT01632.1 - 6.8e-13 49.4 0.0 1e-11 45.6 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase AAA_17 PF13207.6 KXT01632.1 - 1.1e-11 45.3 0.0 3.6e-11 43.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain Hydrolase PF00702.26 KXT01632.1 - 9.2e-05 22.8 0.0 0.00019 21.8 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase NB-ARC PF00931.22 KXT01632.1 - 0.00065 19.0 0.0 0.023 13.9 0.0 2.6 3 0 0 3 3 3 1 NB-ARC domain Pribosyltran PF00156.27 KXT01632.1 - 0.00097 18.7 0.1 0.0037 16.8 0.1 1.9 1 1 0 1 1 1 1 Phosphoribosyl transferase domain AAA_30 PF13604.6 KXT01632.1 - 0.0018 18.0 0.0 0.85 9.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KXT01632.1 - 0.0033 17.8 0.0 0.0082 16.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KXT01632.1 - 0.0083 16.2 0.0 0.77 9.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KXT01632.1 - 0.011 16.0 0.0 0.068 13.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain PRTase_2 PF15609.6 KXT01632.1 - 0.014 14.9 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosyl transferase cobW PF02492.19 KXT01632.1 - 0.02 14.5 0.0 0.058 13.0 0.0 1.8 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 KXT01632.1 - 0.021 15.4 0.0 0.077 13.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain RYDR_ITPR PF01365.21 KXT01632.1 - 0.022 14.2 0.7 0.047 13.1 0.7 1.5 1 0 0 1 1 1 0 RIH domain AAA_16 PF13191.6 KXT01632.1 - 0.027 14.9 0.0 0.13 12.7 0.0 2.2 2 1 1 3 3 3 0 AAA ATPase domain Hydrolase_3 PF08282.12 KXT01632.1 - 0.028 14.2 0.1 0.079 12.7 0.0 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase AAA_24 PF13479.6 KXT01632.1 - 0.032 14.0 0.1 0.19 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KXT01632.1 - 0.076 12.3 0.1 0.49 9.6 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin DUF2075 PF09848.9 KXT01632.1 - 0.084 12.1 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 KXT01632.1 - 0.095 13.0 0.1 0.56 10.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 KXT01632.1 - 0.16 11.1 0.0 0.49 9.6 0.0 1.8 2 0 0 2 2 2 0 KAP family P-loop domain AAA_18 PF13238.6 KXT01633.1 - 0.0071 16.9 0.0 0.034 14.7 0.0 2.1 3 0 0 3 3 3 1 AAA domain MeaB PF03308.16 KXT01633.1 - 0.055 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 KXT01633.1 - 0.1 12.2 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.22 KXT01633.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PRK PF00485.18 KXT01633.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family TsaE PF02367.17 KXT01633.1 - 0.13 12.3 0.0 0.35 10.9 0.0 1.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KXT01633.1 - 0.15 12.3 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KXT01633.1 - 0.17 11.8 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.6 KXT01633.1 - 0.19 11.8 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain PetL PF05115.14 KXT01634.1 - 0.15 12.1 0.7 0.21 11.6 0.7 1.2 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit VI (PetL) Thiolase_N PF00108.23 KXT01635.1 - 1.9e-91 306.1 2.5 2.6e-91 305.6 1.1 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXT01635.1 - 1.1e-46 157.5 1.6 1.3e-45 154.0 1.0 2.3 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KXT01635.1 - 1.9e-06 27.7 3.7 7.7e-05 22.4 1.3 3.5 3 1 1 4 4 4 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KXT01635.1 - 0.0061 16.4 3.8 0.46 10.4 0.1 3.0 3 0 0 3 3 3 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SpoVAD PF07451.11 KXT01635.1 - 0.011 14.4 0.8 0.047 12.4 0.1 2.0 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) GMC_oxred_N PF00732.19 KXT01638.1 - 9.4e-31 107.3 0.0 1.9e-30 106.3 0.0 1.5 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXT01638.1 - 2.3e-29 102.8 0.0 6.4e-29 101.3 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KXT01638.1 - 5.1e-05 23.4 0.1 0.00018 21.7 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXT01638.1 - 0.00024 20.3 0.0 0.00052 19.2 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KXT01638.1 - 0.00098 18.4 0.0 0.0035 16.6 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXT01638.1 - 0.0018 17.4 0.0 0.0025 16.9 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 KXT01638.1 - 0.074 11.7 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein PTCRA PF15028.6 KXT01638.1 - 0.097 12.4 0.0 0.27 10.9 0.0 1.7 1 0 0 1 1 1 0 Pre-T-cell antigen receptor MelC1 PF06236.11 KXT01638.1 - 0.11 12.6 0.1 0.3 11.2 0.1 1.7 1 0 0 1 1 1 0 Tyrosinase co-factor MelC1 ApbA PF02558.16 KXT01638.1 - 0.16 11.6 0.2 0.31 10.7 0.2 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA adh_short PF00106.25 KXT01639.1 - 9.2e-87 289.5 8.9 6.6e-48 162.8 0.6 2.6 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXT01639.1 - 1e-66 224.9 2.0 1e-35 123.4 0.1 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 KXT01639.1 - 1.4e-32 111.8 0.1 4.3e-32 110.3 0.0 1.9 2 0 0 2 2 2 1 MaoC like domain KR PF08659.10 KXT01639.1 - 3.3e-30 105.3 2.1 5.1e-14 52.6 0.1 2.4 2 0 0 2 2 2 2 KR domain MaoC_dehydrat_N PF13452.6 KXT01639.1 - 0.019 15.1 0.0 1.4 9.1 0.0 2.4 2 0 0 2 2 2 0 N-terminal half of MaoC dehydratase THF_DHG_CYH_C PF02882.19 KXT01639.1 - 0.054 12.8 0.2 12 5.2 0.1 2.5 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain FAM25 PF15825.5 KXT01639.1 - 0.16 12.3 2.0 0.51 10.7 0.2 2.5 2 0 0 2 2 2 0 FAM25 family PALP PF00291.25 KXT01639.1 - 2.1 7.7 8.0 0.11 11.9 0.2 2.6 3 0 0 3 3 3 0 Pyridoxal-phosphate dependent enzyme Sel1 PF08238.12 KXT01640.1 - 2.8e-28 97.7 33.8 6.1e-05 23.6 0.1 7.4 7 0 0 7 7 7 7 Sel1 repeat Sel1 PF08238.12 KXT01641.1 - 2.8e-28 97.7 33.8 6.1e-05 23.6 0.1 7.4 7 0 0 7 7 7 7 Sel1 repeat F-box PF00646.33 KXT01652.1 - 0.011 15.6 0.1 0.022 14.6 0.1 1.4 1 0 0 1 1 1 0 F-box domain VIT1 PF01988.19 KXT01653.1 - 0.22 11.4 0.0 0.22 11.4 0.0 2.3 3 0 0 3 3 3 0 VIT family VIT1 PF01988.19 KXT01654.1 - 0.23 11.3 0.0 0.23 11.3 0.0 2.2 3 0 0 3 3 3 0 VIT family F-box-like_2 PF13013.6 KXT01656.1 - 0.011 15.7 0.1 6.8 6.7 0.0 2.9 2 1 0 2 2 2 0 F-box-like domain Drc1-Sld2 PF11719.8 KXT01657.1 - 8.7e-80 269.5 32.4 1.3e-79 268.9 32.4 1.2 1 0 0 1 1 1 1 DNA replication and checkpoint protein GPP34 PF05719.11 KXT01658.1 - 3.8e-69 232.8 1.7 4.8e-69 232.5 1.7 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) RPN13_C PF16550.5 KXT01660.1 - 0.069 13.3 0.0 0.14 12.3 0.0 1.5 1 1 0 1 1 1 0 UCH-binding domain NARP1 PF12569.8 KXT01662.1 - 0.099 11.5 9.6 0.17 10.8 9.6 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 PPL5 PF18168.1 KXT01662.1 - 1.6 7.9 6.7 3.6 6.8 6.7 1.6 1 0 0 1 1 1 0 Prim-pol family 5 5_nucleotid_C PF02872.18 KXT01663.1 - 9.7e-38 129.9 0.0 2.6e-37 128.5 0.0 1.7 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KXT01663.1 - 4.2e-09 37.2 0.6 2.6e-08 34.6 0.2 2.0 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase YmdB PF13277.6 KXT01663.1 - 0.0013 18.2 0.1 0.0051 16.2 0.1 1.9 2 0 0 2 2 2 1 YmdB-like protein Hexokinase_2 PF03727.16 KXT01664.1 - 3.2e-83 278.8 0.0 4.4e-83 278.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KXT01664.1 - 4.1e-72 242.3 0.0 1.2e-71 240.7 0.0 1.7 2 0 0 2 2 2 1 Hexokinase Hexokinase_2 PF03727.16 KXT01665.1 - 3.2e-83 278.8 0.0 4.4e-83 278.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KXT01665.1 - 4.1e-72 242.3 0.0 1.2e-71 240.7 0.0 1.7 2 0 0 2 2 2 1 Hexokinase Ammonium_transp PF00909.21 KXT01666.1 - 4.2e-113 378.0 26.1 4.9e-113 377.8 26.1 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Clat_adaptor_s PF01217.20 KXT01667.1 - 4.2e-15 55.9 1.0 3.8e-14 52.8 1.0 1.9 1 1 0 1 1 1 1 Clathrin adaptor complex small chain F-box-like PF12937.7 KXT01668.1 - 0.0016 18.3 0.0 0.0041 17.0 0.0 1.7 1 0 0 1 1 1 1 F-box-like NIF PF03031.18 KXT01669.1 - 2e-27 95.9 0.0 3.7e-27 95.0 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BRCT PF00533.26 KXT01669.1 - 5.7e-07 29.8 0.1 1.5e-06 28.5 0.1 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KXT01669.1 - 0.00013 21.9 0.8 0.00031 20.6 0.8 1.7 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 KXT01669.1 - 0.0007 20.0 0.0 0.0023 18.3 0.0 1.9 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 KXT01669.1 - 0.0025 17.7 0.0 0.0064 16.4 0.0 1.7 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain LIG3_BRCT PF16759.5 KXT01669.1 - 0.0047 17.2 0.2 0.031 14.6 0.7 2.1 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain DUF3646 PF12362.8 KXT01669.1 - 7.9 6.8 9.7 9.8 6.5 1.1 2.8 1 1 1 2 2 2 0 DNA polymerase III gamma and tau subunits C terminal zf-C2H2 PF00096.26 KXT01670.1 - 1.7e-05 25.0 17.7 0.2 12.2 0.1 4.3 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 KXT01670.1 - 0.0058 17.3 0.8 0.045 14.4 0.9 2.3 2 0 0 2 2 2 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_6 PF13912.6 KXT01670.1 - 0.0058 16.6 0.1 4.7 7.3 0.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXT01670.1 - 0.22 12.0 14.0 0.21 12.1 0.3 3.7 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXT01670.1 - 0.23 12.4 11.7 8.1 7.6 3.9 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KXT01670.1 - 0.23 11.6 1.2 0.63 10.2 1.2 1.8 1 0 0 1 1 1 0 Zinc ribbon domain zf-C2HE PF16278.5 KXT01670.1 - 0.38 11.2 2.1 1.2 9.6 2.1 1.9 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger DRIM PF07539.12 KXT01671.1 - 3.4e-163 544.3 1.9 3.4e-163 544.3 1.9 4.1 5 0 0 5 5 5 2 Down-regulated in metastasis CLASP_N PF12348.8 KXT01671.1 - 0.0021 17.7 4.4 0.11 12.0 0.0 4.9 6 0 0 6 6 6 1 CLASP N terminal GlutR_dimer PF00745.20 KXT01671.1 - 0.0038 17.6 1.6 1.5 9.3 0.0 4.9 3 0 0 3 3 3 1 Glutamyl-tRNAGlu reductase, dimerisation domain tRNA-Thr_ED PF08915.11 KXT01671.1 - 0.18 11.8 0.5 9.2 6.3 0.0 3.4 3 0 0 3 3 3 0 Archaea-specific editing domain of threonyl-tRNA synthetase ParcG PF10274.9 KXT01671.1 - 0.36 10.9 1.2 32 4.6 0.0 3.8 4 0 0 4 4 4 0 Parkin co-regulated protein Sec7_N PF12783.7 KXT01671.1 - 0.71 9.8 16.7 18 5.2 0.0 8.3 9 1 1 10 10 10 0 Guanine nucleotide exchange factor in Golgi transport N-terminal HEAT_EZ PF13513.6 KXT01671.1 - 2.4 8.8 10.4 42 4.8 0.0 6.5 6 0 0 6 6 6 0 HEAT-like repeat RIX1 PF08167.12 KXT01671.1 - 5.6 6.7 6.7 15 5.3 0.0 5.2 6 0 0 6 6 6 0 rRNA processing/ribosome biogenesis Acyl_transf_3 PF01757.22 KXT01672.1 - 5.2e-32 111.3 42.6 6.3e-32 111.0 42.6 1.1 1 0 0 1 1 1 1 Acyltransferase family Na_K-ATPase PF00287.18 KXT01672.1 - 0.11 11.7 1.6 0.19 10.9 1.6 1.3 1 0 0 1 1 1 0 Sodium / potassium ATPase beta chain Malic_M PF03949.15 KXT01673.1 - 9.4e-92 306.9 0.0 1.3e-91 306.5 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KXT01673.1 - 1e-63 214.4 0.0 2.1e-63 213.4 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain p450 PF00067.22 KXT01674.1 - 5.9e-60 203.3 0.0 1.1e-59 202.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 RabGAP-TBC PF00566.18 KXT01675.1 - 1.1e-33 116.7 0.0 1.7e-33 116.1 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ubiquitin PF00240.23 KXT01679.1 - 4.6e-34 116.0 0.6 8e-34 115.2 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 KXT01679.1 - 8.9e-26 89.8 2.2 8.9e-26 89.8 2.2 2.0 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 KXT01679.1 - 2.6e-16 59.2 0.7 5e-16 58.3 0.7 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KXT01679.1 - 2.9e-05 24.4 0.5 0.00013 22.4 0.1 2.1 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KXT01679.1 - 0.0015 18.6 0.6 0.0035 17.4 0.6 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KXT01679.1 - 0.0047 17.3 0.9 0.0083 16.5 0.0 1.7 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KXT01679.1 - 0.0055 16.6 0.0 0.0083 16.0 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 KXT01679.1 - 0.013 16.1 0.8 0.018 15.6 0.8 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 KXT01679.1 - 0.021 14.9 1.0 5.9 7.0 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain BTB PF00651.31 KXT01680.1 - 1.1e-07 32.1 0.0 1.4e-06 28.5 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain UBA_5 PF16577.5 KXT01680.1 - 0.079 13.1 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 UBA domain FMN_bind PF04205.14 KXT01682.1 - 0.19 12.3 1.6 0.36 11.4 1.6 1.5 1 1 0 1 1 1 0 FMN-binding domain Sun2_CC2 PF18580.1 KXT01683.1 - 0.17 12.1 0.8 0.38 11.0 0.8 1.5 1 0 0 1 1 1 0 SUN2 coiled coil domain 2 PP-binding PF00550.25 KXT01684.1 - 2.3e-11 43.9 0.2 3.4e-11 43.3 0.2 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 KXT01684.1 - 8.6e-06 25.9 0.1 1.4e-05 25.2 0.1 1.3 1 0 0 1 1 1 1 Acyl-carrier TAD2 PF18521.1 KXT01684.1 - 0.16 12.0 0.0 0.43 10.6 0.0 1.7 1 0 0 1 1 1 0 Transactivation domain 2 F-box PF00646.33 KXT01685.1 - 0.015 15.2 0.0 0.022 14.6 0.0 1.2 1 0 0 1 1 1 0 F-box domain BPTA PF17044.5 KXT01685.1 - 0.13 12.1 0.0 0.15 11.9 0.0 1.0 1 0 0 1 1 1 0 Borrelial persistence in ticks protein A Gly_transf_sug PF04488.15 KXT01686.1 - 8.7e-13 48.7 0.1 1.8e-12 47.8 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif WD40 PF00400.32 KXT01687.1 - 6.9e-08 33.0 3.7 0.53 11.2 0.0 5.4 6 0 0 6 6 6 4 WD domain, G-beta repeat LCM PF04072.14 KXT01688.1 - 5.5e-25 88.4 0.0 9.8e-25 87.6 0.0 1.4 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase HlyD_D4 PF16572.5 KXT01688.1 - 0.043 13.7 0.1 0.089 12.7 0.1 1.5 1 0 0 1 1 1 0 Long alpha hairpin domain of cation efflux system protein, CusB Mito_carr PF00153.27 KXT01689.1 - 9.1e-45 150.5 0.7 2.6e-17 62.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CDKN3 PF05706.12 KXT01689.1 - 0.21 11.2 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Vma12 PF11712.8 KXT01690.1 - 4.1e-44 150.0 0.0 5.5e-44 149.6 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF2569 PF10754.9 KXT01690.1 - 0.011 16.2 0.2 0.016 15.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) PBP_N PF17093.5 KXT01690.1 - 0.66 10.2 3.3 1.1 9.6 0.2 2.2 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus XPG_I PF00867.18 KXT01693.1 - 7.5e-31 106.3 1.9 1.8e-30 105.1 0.0 2.3 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 KXT01693.1 - 2.6e-30 104.9 0.0 7.7e-30 103.4 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 KXT01693.1 - 1.3e-05 25.7 2.0 3.9e-05 24.2 0.0 2.5 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold AHD PF17793.1 KXT01693.1 - 0.018 14.8 0.0 0.047 13.5 0.0 1.7 1 0 0 1 1 1 0 ANC1 homology domain (AHD) HXXSHH PF07586.11 KXT01693.1 - 0.031 13.9 3.0 0.063 12.8 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) AAA_23 PF13476.6 KXT01693.1 - 0.42 11.1 7.7 0.82 10.1 5.7 2.1 2 0 0 2 2 2 0 AAA domain Clat_adaptor_s PF01217.20 KXT01695.1 - 1.2e-55 187.4 0.6 1.4e-55 187.1 0.6 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain MFS_1 PF07690.16 KXT01696.1 - 1.9e-35 122.5 31.5 2.4e-33 115.6 23.3 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXT01696.1 - 2.3e-05 23.5 8.9 2.3e-05 23.5 8.9 2.4 1 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 KXT01696.1 - 8.5e-05 22.0 8.3 0.0022 17.3 1.9 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 KXT01696.1 - 0.00012 20.5 1.8 0.00055 18.4 1.7 2.0 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Abhydrolase_2 PF02230.16 KXT01696.1 - 0.02 14.7 0.3 0.069 12.9 0.0 1.9 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase LacY_symp PF01306.19 KXT01696.1 - 0.025 13.4 0.2 0.025 13.4 0.2 1.9 2 0 0 2 2 2 0 LacY proton/sugar symporter MFS_1_like PF12832.7 KXT01696.1 - 1.7 7.4 21.6 0.2 10.5 0.5 4.0 3 2 1 4 4 4 0 MFS_1 like family DAO PF01266.24 KXT01699.1 - 1.1e-36 127.2 0.0 1.2e-36 127.0 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXT01699.1 - 0.00016 20.9 0.1 0.00033 19.9 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain ThiF PF00899.21 KXT01699.1 - 0.00025 20.5 0.0 0.0004 19.8 0.0 1.2 1 0 0 1 1 1 1 ThiF family Pyr_redox_2 PF07992.14 KXT01699.1 - 0.00077 18.8 0.0 0.82 8.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXT01699.1 - 0.0013 18.9 0.0 0.0031 17.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KXT01699.1 - 0.0014 17.8 0.0 0.3 10.1 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A Shikimate_DH PF01488.20 KXT01699.1 - 0.0048 17.0 0.0 0.0085 16.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 KXT01699.1 - 0.0074 16.3 0.1 2.1 8.3 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KXT01699.1 - 0.0077 15.1 0.2 0.087 11.7 0.2 2.2 1 1 0 1 1 1 1 Tryptophan halogenase NAD_binding_7 PF13241.6 KXT01699.1 - 0.14 12.6 0.0 0.4 11.1 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 KXT01699.1 - 0.15 11.2 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_Gly3P_dh_N PF01210.23 KXT01699.1 - 0.21 11.5 0.0 0.38 10.7 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 KXT01699.1 - 0.22 11.4 0.0 0.4 10.5 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Asp PF00026.23 KXT01701.1 - 5.7e-108 361.1 0.1 7.3e-108 360.7 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXT01701.1 - 2.5e-15 57.2 1.3 5.1e-13 49.6 0.9 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 KXT01701.1 - 0.00038 21.0 0.0 0.59 10.7 0.0 2.9 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KXT01701.1 - 0.00044 20.8 0.1 2.5 8.8 0.0 3.3 2 2 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 KXT01701.1 - 0.0023 17.8 0.0 0.012 15.3 0.0 2.1 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal MBOAT PF03062.19 KXT01702.1 - 1.1e-44 153.2 20.6 3.2e-44 151.7 11.0 2.2 2 0 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 KXT01702.1 - 2.8e-06 27.5 4.9 7.2e-06 26.2 4.9 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family ATP-synt_8 PF00895.20 KXT01702.1 - 0.31 11.5 5.4 2.1 8.9 0.0 3.7 3 0 0 3 3 3 0 ATP synthase protein 8 BTB PF00651.31 KXT01704.1 - 1.2e-07 32.0 0.0 1.1e-05 25.6 0.0 2.6 3 0 0 3 3 3 2 BTB/POZ domain BTB PF00651.31 KXT01705.1 - 1.1e-06 28.9 0.0 1.9e-06 28.1 0.0 1.5 2 0 0 2 2 2 1 BTB/POZ domain DUF1048 PF06304.11 KXT01705.1 - 0.1 13.1 0.0 0.24 11.8 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1048) Glyco_hydro_76 PF03663.14 KXT01706.1 - 5e-45 154.6 16.7 6.4e-45 154.2 16.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KXT01706.1 - 1.4e-05 24.4 0.1 0.0058 15.8 0.0 3.1 2 1 2 4 4 4 2 Glycosyl Hydrolase Family 88 FtsJ PF01728.19 KXT01707.1 - 1.7e-53 181.3 0.0 2.2e-53 181.0 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 KXT01707.1 - 0.05 13.4 0.0 0.082 12.7 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain HET PF06985.11 KXT01708.1 - 3.3e-09 37.2 3.3 8.1e-08 32.7 0.3 4.4 2 2 1 3 3 3 2 Heterokaryon incompatibility protein (HET) betaPIX_CC PF16523.5 KXT01708.1 - 0.029 14.2 1.0 0.029 14.2 1.0 4.8 4 1 1 6 6 6 0 betaPIX coiled coil WDCP PF15390.6 KXT01708.1 - 4.9 5.4 13.7 6.6 5.0 13.7 1.3 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family DOPA_dioxygen PF08883.11 KXT01709.1 - 5.6e-43 145.5 0.1 7e-43 145.2 0.1 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family Ribosomal_L11 PF00298.19 KXT01710.1 - 8.5e-25 87.1 2.0 2.1e-24 85.8 2.0 1.7 1 1 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 KXT01710.1 - 5.1e-24 83.9 0.1 5.1e-24 83.9 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain PriC PF07445.12 KXT01711.1 - 0.045 13.7 0.0 0.27 11.1 0.0 2.0 2 0 0 2 2 2 0 Primosomal replication protein priC zf-C2H2 PF00096.26 KXT01714.1 - 3e-10 40.0 3.1 6.8e-06 26.2 0.6 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXT01714.1 - 1.5e-09 37.8 2.0 9.2e-06 26.1 0.3 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KXT01714.1 - 1.3e-05 25.0 0.2 3.2e-05 23.8 0.1 1.8 2 0 0 2 2 2 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXT01714.1 - 2.4e-05 24.5 8.6 0.00095 19.5 0.2 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-Di19 PF05605.12 KXT01714.1 - 0.0024 18.1 2.1 0.0056 16.9 2.1 1.7 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.11 KXT01714.1 - 0.096 12.5 2.9 0.12 12.2 0.1 2.2 1 1 1 2 2 2 0 GAGA factor zf-RING_UBOX PF13445.6 KXT01714.1 - 0.13 12.3 3.8 0.54 10.3 2.3 2.5 2 1 0 2 2 2 0 RING-type zinc-finger Cytochrom_B561 PF03188.16 KXT01715.1 - 7.3e-18 65.0 4.5 1.5e-17 64.0 4.5 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 KXT01715.1 - 0.21 11.7 14.4 0.14 12.3 0.6 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF4079) EF-hand_7 PF13499.6 KXT01716.1 - 1e-23 83.5 8.8 1.6e-15 57.3 0.8 3.7 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 KXT01716.1 - 1.2e-22 77.7 12.6 6.4e-08 31.6 0.2 5.0 5 1 1 6 6 6 3 EF hand EF-hand_6 PF13405.6 KXT01716.1 - 6.1e-22 75.6 6.4 9.7e-06 25.1 0.1 5.8 5 1 1 6 6 6 4 EF-hand domain EF-hand_5 PF13202.6 KXT01716.1 - 3.5e-16 57.9 11.1 0.0001 21.6 0.1 5.0 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 KXT01716.1 - 2e-12 46.8 13.1 8.5e-05 22.3 0.5 4.3 3 2 1 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 KXT01716.1 - 2.8e-07 30.5 7.1 0.0095 15.9 0.2 4.0 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KXT01716.1 - 0.00077 19.7 0.2 0.022 15.1 0.0 2.9 1 1 1 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.9 KXT01716.1 - 0.00094 19.5 3.1 1.5 9.1 0.3 3.4 2 2 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region DUF3953 PF13129.6 KXT01716.1 - 0.01 15.6 0.1 0.021 14.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3953) EF-hand_10 PF14788.6 KXT01716.1 - 0.88 9.5 3.3 2.5 8.0 0.0 3.2 5 0 0 5 5 5 0 EF hand FAD_SOX PF18371.1 KXT01717.1 - 0.029 14.7 0.4 0.099 13.0 0.0 2.1 2 0 0 2 2 2 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase polyprenyl_synt PF00348.17 KXT01718.1 - 7.8e-71 238.1 0.0 1.5e-70 237.2 0.0 1.5 1 1 0 1 1 1 1 Polyprenyl synthetase Ank_2 PF12796.7 KXT01718.1 - 1.9e-17 63.6 0.7 2.3e-07 31.3 0.3 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXT01718.1 - 3.6e-16 59.0 2.7 1.4e-09 38.0 0.3 4.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXT01718.1 - 1.9e-12 47.4 2.2 6.1e-06 26.7 0.1 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXT01718.1 - 1.1e-10 40.7 0.8 0.0048 17.3 0.1 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 KXT01718.1 - 8.6e-09 35.5 8.5 0.00012 22.3 0.9 4.7 3 1 0 3 3 3 3 Ankyrin repeat F-box PF00646.33 KXT01718.1 - 0.0065 16.3 0.1 0.015 15.1 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXT01718.1 - 0.075 12.9 0.9 0.21 11.5 0.9 1.8 1 0 0 1 1 1 0 F-box-like RRM_1 PF00076.22 KXT01719.1 - 3.9e-48 161.1 0.0 1.5e-16 60.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXT01719.1 - 0.0015 18.1 0.0 0.78 9.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KXT01719.1 - 0.013 15.5 0.0 13 5.9 0.0 3.1 3 0 0 3 3 3 0 RNA binding motif RRM_occluded PF16842.5 KXT01719.1 - 0.084 12.7 0.0 18 5.3 0.0 2.5 3 0 0 3 3 3 0 Occluded RNA-recognition motif NrsF PF06532.11 KXT01720.1 - 0.62 9.7 5.8 3.1 7.4 0.3 2.2 1 1 0 2 2 2 0 Negative regulator of sigma F Adeno_PX PF05829.12 KXT01721.1 - 0.0078 16.1 0.1 0.015 15.1 0.1 1.4 1 0 0 1 1 1 1 Adenovirus late L2 mu core protein (Protein X) Pacs-1 PF10254.9 KXT01721.1 - 8.5 5.2 6.2 0.42 9.5 0.1 1.9 2 0 0 2 2 2 0 PACS-1 cytosolic sorting protein CSN8_PSD8_EIF3K PF10075.9 KXT01722.1 - 2.1e-20 73.1 0.0 3.2e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 KXT01722.1 - 1.9e-06 27.5 0.0 2.7e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP family COG6 PF06419.11 KXT01723.1 - 7.1e-206 685.2 10.5 8.1e-206 685.0 10.5 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 COG2 PF06148.11 KXT01723.1 - 0.0025 17.9 0.2 0.0025 17.9 0.2 2.8 4 0 0 4 4 4 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF1043 PF06295.12 KXT01723.1 - 0.0095 15.9 1.1 2 8.4 0.0 3.6 3 1 0 3 3 3 1 Protein of unknown function (DUF1043) CENP-F_leu_zip PF10473.9 KXT01723.1 - 0.015 15.3 0.1 0.071 13.1 0.1 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Sec34 PF04136.15 KXT01723.1 - 0.025 14.4 2.5 1.2 9.0 0.2 3.7 4 0 0 4 4 4 0 Sec34-like family Gp-FAR-1 PF05823.12 KXT01723.1 - 0.082 13.3 0.3 20 5.5 0.0 2.7 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF4225 PF13988.6 KXT01723.1 - 0.099 12.2 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4225) DUF948 PF06103.11 KXT01723.1 - 0.12 12.6 0.7 0.87 9.9 0.1 2.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) S4 PF01479.25 KXT01723.1 - 0.23 11.2 0.5 7.2 6.4 0.0 2.4 2 0 0 2 2 2 0 S4 domain RasGAP PF00616.19 KXT01724.1 - 2.1e-58 197.4 0.5 6.6e-58 195.8 0.0 2.1 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 KXT01724.1 - 3.7e-30 104.9 4.2 3.7e-30 104.9 4.2 2.7 3 0 0 3 3 3 1 RasGAP C-terminus OMP_b-brl PF13505.6 KXT01725.1 - 0.012 15.7 9.2 0.021 14.9 9.2 1.4 1 0 0 1 1 1 0 Outer membrane protein beta-barrel domain OMP_b-brl PF13505.6 KXT01727.1 - 0.012 15.7 9.2 0.021 14.9 9.2 1.4 1 0 0 1 1 1 0 Outer membrane protein beta-barrel domain Bac_luciferase PF00296.20 KXT01729.1 - 3.7e-61 207.3 0.4 5.3e-61 206.8 0.4 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase 2-Hacid_dh_C PF02826.19 KXT01730.1 - 7.2e-38 129.7 0.0 1e-37 129.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXT01730.1 - 2.2e-11 43.5 0.0 3.2e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.17 KXT01730.1 - 0.015 15.9 0.0 0.031 14.9 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.21 KXT01730.1 - 0.057 13.5 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.15 KXT01730.1 - 0.11 12.7 0.1 0.22 11.7 0.0 1.5 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 KXT01731.1 - 7.2e-38 129.7 0.0 1e-37 129.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXT01731.1 - 2.2e-11 43.5 0.0 3.2e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.17 KXT01731.1 - 0.015 15.9 0.0 0.031 14.9 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.21 KXT01731.1 - 0.057 13.5 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.15 KXT01731.1 - 0.11 12.7 0.1 0.22 11.7 0.0 1.5 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 KXT01732.1 - 7.2e-38 129.7 0.0 1e-37 129.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXT01732.1 - 2.2e-11 43.5 0.0 3.2e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.17 KXT01732.1 - 0.015 15.9 0.0 0.031 14.9 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.21 KXT01732.1 - 0.057 13.5 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.15 KXT01732.1 - 0.11 12.7 0.1 0.22 11.7 0.0 1.5 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase PAP2_3 PF14378.6 KXT01733.1 - 6.7e-24 84.6 12.4 6.7e-24 84.6 12.4 1.8 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 KXT01733.1 - 6.5e-10 38.9 5.7 6.5e-10 38.9 5.7 1.8 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 KXT01733.1 - 4.9 7.8 11.2 0.14 12.7 3.1 2.5 2 1 0 2 2 2 0 PAP2 superfamily C-terminal NADH_dhqG_C PF09326.11 KXT01734.1 - 0.17 12.6 0.0 0.23 12.2 0.0 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit G, C-terminal Ribophorin_I PF04597.14 KXT01735.1 - 5.4e-151 503.7 2.1 6.1e-151 503.6 2.1 1.0 1 0 0 1 1 1 1 Ribophorin I BolA PF01722.18 KXT01737.1 - 2.3e-17 63.0 0.1 4.7e-17 62.0 0.1 1.5 1 1 0 1 1 1 1 BolA-like protein BolA PF01722.18 KXT01738.1 - 2.3e-17 63.0 0.1 4.7e-17 62.0 0.1 1.5 1 1 0 1 1 1 1 BolA-like protein TRP PF06011.12 KXT01739.1 - 4e-141 470.6 21.7 5.4e-141 470.2 21.7 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KXT01739.1 - 2.1e-40 138.3 0.6 3.9e-40 137.4 0.6 1.5 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.15 KXT01739.1 - 3.6e-06 27.5 0.3 6.8e-06 26.5 0.3 1.4 1 0 0 1 1 1 1 ML domain Phage_SSB PF16773.5 KXT01739.1 - 0.066 13.3 0.2 0.19 11.8 0.2 1.7 1 0 0 1 1 1 0 Lactococcus phage single-stranded DNA binding protein EphA2_TM PF14575.6 KXT01739.1 - 3.6 8.6 5.7 15 6.6 0.0 3.5 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain Pil1 PF13805.6 KXT01740.1 - 1.3e-93 313.3 9.3 1.8e-93 312.9 9.3 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 NIF3 PF01784.18 KXT01741.1 - 3.8e-61 206.8 0.0 5e-61 206.4 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Glyco_trans_2_3 PF13632.6 KXT01742.1 - 6.7e-24 84.9 1.7 1.3e-23 84.0 1.7 1.5 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_trans_2_3 PF13632.6 KXT01743.1 - 6.7e-24 84.9 1.7 1.3e-23 84.0 1.7 1.5 1 0 0 1 1 1 1 Glycosyl transferase family group 2 DUF2256 PF10013.9 KXT01744.1 - 2.4e-05 24.4 3.9 9e-05 22.5 3.9 2.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2256) LAP1C PF05609.12 KXT01744.1 - 0.063 12.4 1.1 0.098 11.7 1.1 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) TTL PF03133.15 KXT01744.1 - 0.12 11.4 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Tubulin-tyrosine ligase family STIMATE PF12400.8 KXT01745.1 - 5.1e-41 140.1 2.8 8.5e-41 139.4 2.8 1.3 1 0 0 1 1 1 1 STIMATE family FKBP_C PF00254.28 KXT01745.1 - 2.3e-32 111.2 0.0 3.4e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase RPEL PF02755.15 KXT01745.1 - 5.1 6.9 4.6 1.6 8.5 0.3 2.2 2 0 0 2 2 2 0 RPEL repeat STIMATE PF12400.8 KXT01746.1 - 5.1e-41 140.1 2.8 8.5e-41 139.4 2.8 1.3 1 0 0 1 1 1 1 STIMATE family FKBP_C PF00254.28 KXT01746.1 - 2.3e-32 111.2 0.0 3.4e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase RPEL PF02755.15 KXT01746.1 - 5.1 6.9 4.6 1.6 8.5 0.3 2.2 2 0 0 2 2 2 0 RPEL repeat Lipase_2 PF01674.18 KXT01747.1 - 1.9e-08 34.1 0.0 1.5e-07 31.2 0.0 2.0 1 1 0 1 1 1 1 Lipase (class 2) Abhydrolase_1 PF00561.20 KXT01747.1 - 0.00022 20.9 0.2 0.00086 19.0 0.2 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXT01747.1 - 0.0003 20.1 0.0 0.00048 19.5 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Palm_thioest PF02089.15 KXT01747.1 - 0.00087 19.2 0.1 0.0094 15.8 0.0 2.3 2 1 1 3 3 3 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 KXT01747.1 - 0.00099 19.8 0.0 0.0019 18.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.12 KXT01747.1 - 0.019 14.5 0.0 0.032 13.7 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_8 PF06259.12 KXT01747.1 - 0.069 12.8 0.0 0.81 9.3 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase DUF676 PF05057.14 KXT01747.1 - 0.071 12.6 0.0 0.17 11.4 0.0 1.5 1 1 0 1 1 1 0 Putative serine esterase (DUF676) STIMATE PF12400.8 KXT01748.1 - 5.1e-41 140.1 2.8 8.5e-41 139.4 2.8 1.3 1 0 0 1 1 1 1 STIMATE family FKBP_C PF00254.28 KXT01748.1 - 2.3e-32 111.2 0.0 3.4e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase RPEL PF02755.15 KXT01748.1 - 5.1 6.9 4.6 1.6 8.5 0.3 2.2 2 0 0 2 2 2 0 RPEL repeat DUF2256 PF10013.9 KXT01749.1 - 2.4e-05 24.4 3.9 9e-05 22.5 3.9 2.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2256) LAP1C PF05609.12 KXT01749.1 - 0.063 12.4 1.1 0.098 11.7 1.1 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) TTL PF03133.15 KXT01749.1 - 0.12 11.4 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Tubulin-tyrosine ligase family STIMATE PF12400.8 KXT01750.1 - 5.1e-41 140.1 2.8 8.5e-41 139.4 2.8 1.3 1 0 0 1 1 1 1 STIMATE family FKBP_C PF00254.28 KXT01750.1 - 2.3e-32 111.2 0.0 3.4e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase RPEL PF02755.15 KXT01750.1 - 5.1 6.9 4.6 1.6 8.5 0.3 2.2 2 0 0 2 2 2 0 RPEL repeat F-box PF00646.33 KXT01751.1 - 0.0069 16.2 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXT01751.1 - 0.013 15.4 0.2 0.027 14.4 0.2 1.6 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 KXT01752.1 - 0.0069 16.2 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXT01752.1 - 0.013 15.4 0.2 0.027 14.4 0.2 1.6 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 KXT01753.1 - 0.0069 16.2 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXT01753.1 - 0.013 15.4 0.2 0.027 14.4 0.2 1.6 1 0 0 1 1 1 0 F-box-like DUF2256 PF10013.9 KXT01754.1 - 2.5e-05 24.3 3.9 7.8e-05 22.7 3.9 1.8 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2256) LAP1C PF05609.12 KXT01754.1 - 0.05 12.7 1.1 0.077 12.1 1.1 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) TTL PF03133.15 KXT01754.1 - 0.1 11.7 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Tubulin-tyrosine ligase family TFIIIC_delta PF12657.7 KXT01755.1 - 1.6e-35 122.7 0.3 6.4e-35 120.7 0.3 2.1 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 KXT01755.1 - 5.4e-20 71.2 0.9 1.2e-19 70.1 0.9 1.5 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex F-box PF00646.33 KXT01757.1 - 5.9e-08 32.4 0.0 1.1e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXT01757.1 - 0.00033 20.5 0.1 0.0006 19.7 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXT01758.1 - 5.9e-08 32.4 0.0 1.1e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXT01758.1 - 0.00033 20.5 0.1 0.0006 19.7 0.1 1.5 1 0 0 1 1 1 1 F-box-like Glyco_transf_24 PF18404.1 KXT01759.1 - 1.9e-149 496.4 2.9 2.9e-149 495.8 2.9 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 KXT01759.1 - 3.5e-68 230.3 0.0 9.7e-68 228.9 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 KXT01759.1 - 1.3e-48 165.4 0.4 2.5e-48 164.5 0.4 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 KXT01759.1 - 3.7e-46 156.4 1.4 6.9e-45 152.3 0.2 3.1 3 0 0 3 3 3 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 KXT01759.1 - 2.6e-40 136.9 0.0 5.1e-40 136.0 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_15 PF18403.1 KXT01759.1 - 2.6e-36 125.6 0.0 1.5e-35 123.0 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 KXT01759.1 - 0.0027 17.3 0.1 0.0052 16.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 Oxidored_FMN PF00724.20 KXT01760.1 - 8.2e-63 212.7 0.0 1.1e-62 212.3 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 KXT01760.1 - 0.03 13.4 0.0 1.3 8.1 0.0 2.2 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) Sulfotransfer_3 PF13469.6 KXT01761.1 - 0.0057 17.1 0.1 0.11 12.9 0.0 2.6 2 1 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 KXT01761.1 - 0.014 14.9 0.2 0.045 13.2 0.1 1.8 2 0 0 2 2 2 0 Sulfotransferase domain Glyco_hydro_cc PF11790.8 KXT01762.1 - 2e-72 243.6 5.5 2.3e-72 243.4 5.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core EF1G PF00647.19 KXT01762.1 - 0.017 15.2 0.3 0.035 14.2 0.3 1.4 1 0 0 1 1 1 0 Elongation factor 1 gamma, conserved domain Glyco_hydro_cc PF11790.8 KXT01763.1 - 2e-72 243.6 5.5 2.3e-72 243.4 5.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core EF1G PF00647.19 KXT01763.1 - 0.017 15.2 0.3 0.035 14.2 0.3 1.4 1 0 0 1 1 1 0 Elongation factor 1 gamma, conserved domain Ribosomal_S19 PF00203.21 KXT01777.1 - 3.1e-28 97.5 0.1 3.6e-28 97.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 DEAD PF00270.29 KXT01778.1 - 9.6e-40 136.2 0.1 1.5e-39 135.5 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXT01778.1 - 2e-21 76.4 0.0 8.3e-21 74.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KXT01778.1 - 3.7e-18 65.5 1.0 1e-17 64.1 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KXT01778.1 - 1.5e-06 28.3 0.0 3e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KXT01778.1 - 0.0068 15.6 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase CMAS PF02353.20 KXT01780.1 - 1e-65 221.8 0.0 2.1e-64 217.5 0.0 2.1 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 KXT01780.1 - 1.7e-11 44.6 0.0 4.1e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXT01780.1 - 5.6e-11 42.9 0.0 1.5e-10 41.5 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXT01780.1 - 3.9e-09 36.5 0.0 1.2e-08 34.9 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXT01780.1 - 9.9e-09 35.2 0.0 1.6e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXT01780.1 - 2.3e-06 28.3 0.0 6.4e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 KXT01780.1 - 0.001 18.2 0.0 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_3 PF01596.17 KXT01780.1 - 0.0032 16.7 0.0 0.0052 16.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase PCMT PF01135.19 KXT01780.1 - 0.031 14.0 0.0 0.052 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.16 KXT01780.1 - 0.032 14.0 0.0 0.052 13.3 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein DUF938 PF06080.12 KXT01780.1 - 0.045 13.5 0.0 0.18 11.5 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF938) Ubie_methyltran PF01209.18 KXT01780.1 - 0.047 13.0 0.0 0.089 12.1 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 KXT01780.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase ATP-synt_C PF00137.21 KXT01781.1 - 1.3e-24 86.2 24.7 3.4e-15 56.1 10.6 3.0 3 0 0 3 3 3 2 ATP synthase subunit C SLATT_5 PF18160.1 KXT01781.1 - 0.038 13.3 0.1 0.038 13.3 0.1 1.9 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 adh_short_C2 PF13561.6 KXT01783.1 - 2.6e-51 174.5 1.1 5.1e-51 173.5 1.1 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXT01783.1 - 3.5e-42 144.1 0.7 5.9e-42 143.3 0.7 1.4 1 0 0 1 1 1 1 short chain dehydrogenase MFS_1 PF07690.16 KXT01783.1 - 2.8e-16 59.4 17.6 7.6e-16 58.0 17.2 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily KR PF08659.10 KXT01783.1 - 3.3e-05 23.9 0.5 0.00012 22.1 0.5 1.8 1 1 0 1 1 1 1 KR domain Nodulin-like PF06813.13 KXT01783.1 - 0.0001 21.9 2.7 0.0001 21.9 2.7 2.2 2 0 0 2 2 2 1 Nodulin-like RecX PF02631.16 KXT01783.1 - 0.094 13.2 0.2 0.28 11.6 0.2 1.8 1 0 0 1 1 1 0 RecX family Rabaptin PF03528.15 KXT01783.1 - 0.5 9.0 3.0 0.74 8.4 3.0 1.1 1 0 0 1 1 1 0 Rabaptin SGL PF08450.12 KXT01784.1 - 4.3e-06 26.5 0.1 0.002 17.7 0.1 2.6 1 1 2 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region SBBP PF06739.11 KXT01784.1 - 0.6 10.2 3.8 5.1 7.2 0.1 3.3 3 0 0 3 3 3 0 Beta-propeller repeat Mre11_DNA_bind PF04152.14 KXT01785.1 - 1.2e-49 168.9 0.2 1.2e-49 168.9 0.2 2.1 3 0 0 3 3 3 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 KXT01785.1 - 3.7e-14 53.7 2.1 1.1e-13 52.1 2.1 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXT01785.1 - 0.00018 21.8 0.0 0.0035 17.5 0.0 2.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MFS_1 PF07690.16 KXT01786.1 - 1.2e-39 136.3 23.1 1.7e-39 135.8 23.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1772 PF08592.11 KXT01786.1 - 0.00076 19.8 0.3 0.00076 19.8 0.3 4.0 3 1 0 3 3 3 1 Domain of unknown function (DUF1772) tRNA_U5-meth_tr PF05958.11 KXT01787.1 - 2.8e-12 46.3 0.0 1.5e-11 43.9 0.0 2.1 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.10 KXT01787.1 - 7.7e-05 22.3 0.1 0.00015 21.4 0.1 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 KXT01787.1 - 7.7e-05 23.3 0.0 0.00022 21.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXT01787.1 - 0.0002 21.2 0.1 0.00041 20.2 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KXT01787.1 - 0.0066 15.9 0.1 0.013 14.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KXT01787.1 - 0.0086 16.7 0.0 0.022 15.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltrans_SAM PF10672.9 KXT01787.1 - 0.02 14.0 0.0 0.035 13.2 0.0 1.3 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase MTS PF05175.14 KXT01787.1 - 0.12 12.0 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain ROS_MUCR PF05443.11 KXT01787.1 - 0.12 12.4 0.1 0.3 11.1 0.1 1.6 1 0 0 1 1 1 0 ROS/MUCR transcriptional regulator protein HAD_2 PF13419.6 KXT01788.1 - 1e-18 68.1 0.0 1.9e-18 67.2 0.0 1.5 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXT01788.1 - 2.9e-09 37.5 0.0 4.5e-06 27.1 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase NT5C PF06941.12 KXT01788.1 - 0.02 14.8 0.0 0.16 11.9 0.0 2.0 1 1 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Hydrolase_like PF13242.6 KXT01788.1 - 0.027 14.5 0.0 0.049 13.7 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like F-box PF00646.33 KXT01789.1 - 9.5e-07 28.5 1.1 9.5e-07 28.5 1.1 2.7 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 KXT01789.1 - 0.00048 20.0 2.4 0.00056 19.8 1.0 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXT01790.1 - 9.5e-07 28.5 1.1 9.5e-07 28.5 1.1 2.7 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 KXT01790.1 - 0.00048 20.0 2.4 0.00056 19.8 1.0 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXT01791.1 - 9.2e-07 28.6 1.1 9.2e-07 28.6 1.1 2.7 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 KXT01791.1 - 0.00046 20.0 2.4 0.00054 19.8 1.0 1.8 2 0 0 2 2 2 1 F-box-like CENP-T_C PF15511.6 KXT01792.1 - 0.18 12.0 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold Sad1_UNC PF07738.13 KXT01793.1 - 5e-12 46.0 0.0 3.1e-06 27.3 0.0 2.3 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal Mago_nashi PF02792.14 KXT01793.1 - 0.1 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Mago nashi protein Zn_clus PF00172.18 KXT01794.1 - 3.4e-08 33.5 11.1 5.3e-08 32.8 11.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXT01794.1 - 1.2e-07 31.0 0.0 2.7e-07 29.9 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_M3_N PF08439.10 KXT01795.1 - 0.045 14.0 0.0 0.19 12.0 0.0 2.1 1 0 0 1 1 1 0 Oligopeptidase F Flexi_CP_N PF08358.10 KXT01795.1 - 0.076 13.0 0.1 50 4.0 0.0 3.4 3 0 0 3 3 3 0 Carlavirus coat p450 PF00067.22 KXT01796.1 - 5.6e-62 210.0 0.0 7e-62 209.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.19 KXT01797.1 - 1.5e-14 54.0 0.1 4.3e-10 39.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KXT01797.1 - 1.2e-07 31.9 0.4 2.8e-07 30.7 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXT01797.1 - 5.7e-06 25.8 0.9 4.2e-05 22.9 0.3 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KXT01797.1 - 7.5e-06 25.5 3.6 0.012 15.0 0.0 2.7 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase DAO PF01266.24 KXT01797.1 - 1.7e-05 24.6 2.1 1.7e-05 24.6 2.1 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXT01797.1 - 9.8e-05 21.7 2.4 0.0028 17.0 0.3 2.8 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXT01797.1 - 0.00026 20.2 2.3 0.00038 19.7 1.3 1.8 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 KXT01797.1 - 0.00027 20.1 1.9 0.077 12.0 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Trp_halogenase PF04820.14 KXT01797.1 - 0.00034 19.6 0.5 0.00064 18.7 0.1 1.6 2 1 0 2 2 2 1 Tryptophan halogenase Pyr_redox PF00070.27 KXT01797.1 - 0.0011 19.4 0.8 0.0034 17.9 0.3 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXT01797.1 - 0.0013 18.7 4.1 0.0076 16.2 2.1 2.9 2 1 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.14 KXT01797.1 - 0.0015 17.3 0.0 0.0021 16.9 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein DTW PF03942.15 KXT01797.1 - 0.0087 15.8 0.0 0.01 15.6 0.0 1.2 1 0 0 1 1 1 1 DTW domain GIDA PF01134.22 KXT01797.1 - 0.014 14.5 0.4 0.022 13.9 0.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KXT01797.1 - 0.025 13.9 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KXT01797.1 - 0.028 13.7 0.1 0.052 12.8 0.1 1.4 1 0 0 1 1 1 0 Thi4 family ApbA PF02558.16 KXT01797.1 - 0.081 12.6 0.4 0.17 11.5 0.4 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KXT01797.1 - 0.098 12.5 0.2 0.28 11.1 0.2 1.8 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Kei1 PF08552.11 KXT01798.1 - 4.4e-59 199.6 0.7 5.4e-59 199.3 0.7 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 DUF3775 PF12616.8 KXT01798.1 - 0.082 12.9 0.3 0.17 11.9 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3775) Cpn60_TCP1 PF00118.24 KXT01800.1 - 3.7e-151 504.1 12.7 4.3e-151 503.9 12.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cupin_2 PF07883.11 KXT01801.1 - 0.00087 19.0 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 Cupin domain MAS20 PF02064.15 KXT01802.1 - 1.6e-44 151.2 0.1 1.9e-44 150.9 0.1 1.0 1 0 0 1 1 1 1 MAS20 protein import receptor DUF429 PF04250.13 KXT01802.1 - 0.011 15.5 0.7 2.6 7.8 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF429) MipZ PF09140.11 KXT01802.1 - 0.014 14.7 0.0 0.017 14.4 0.0 1.1 1 0 0 1 1 1 0 ATPase MipZ DUF1018 PF06252.12 KXT01802.1 - 0.054 14.5 0.4 0.08 13.9 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) SUR7 PF06687.12 KXT01803.1 - 1e-07 31.8 0.2 2.8e-06 27.1 0.2 2.1 1 1 0 1 1 1 1 SUR7/PalI family Baculo_PEP_C PF04513.12 KXT01803.1 - 0.032 14.3 0.6 0.059 13.4 0.6 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Amastin PF07344.11 KXT01803.1 - 0.27 11.1 3.5 3.4 7.5 1.3 2.4 2 0 0 2 2 2 0 Amastin surface glycoprotein Fig1 PF12351.8 KXT01803.1 - 0.45 10.4 11.5 0.086 12.8 7.4 1.8 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 DUF2569 PF10754.9 KXT01803.1 - 1.5 9.3 8.7 0.39 11.2 4.6 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2569) EF-hand_6 PF13405.6 KXT01804.1 - 2.7e-07 30.0 0.8 0.032 14.2 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 KXT01804.1 - 1.1e-06 28.9 1.8 1.2e-06 28.9 0.2 1.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KXT01804.1 - 2.5e-05 23.5 0.3 7.2e-05 22.1 0.0 1.9 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 KXT01804.1 - 0.0039 16.6 0.0 0.011 15.2 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 KXT01804.1 - 0.0081 16.0 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair Gag_p6 PF08705.11 KXT01804.1 - 0.22 11.8 0.4 0.54 10.6 0.4 1.6 1 0 0 1 1 1 0 Gag protein p6 SET PF00856.28 KXT01805.1 - 1.5e-11 44.9 5.2 2.1e-11 44.5 0.1 2.3 2 0 0 2 2 2 1 SET domain Macoilin PF09726.9 KXT01805.1 - 0.13 10.8 15.2 0.24 9.9 15.2 1.4 1 0 0 1 1 1 0 Macoilin family Mito_carr PF00153.27 KXT01807.1 - 8.4e-67 221.2 6.3 1.8e-24 85.4 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 KXT01807.1 - 9.9e-21 71.7 5.2 2.7e-05 23.4 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KXT01807.1 - 1e-17 64.3 5.3 9.9e-09 35.5 0.8 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KXT01807.1 - 1.2e-15 56.0 7.8 0.00035 20.3 0.0 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 KXT01807.1 - 7.1e-12 44.3 8.4 0.0013 18.1 0.6 3.9 4 0 0 4 4 4 3 EF hand SPARC_Ca_bdg PF10591.9 KXT01807.1 - 5.5e-09 36.3 0.2 0.00048 20.4 0.1 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 KXT01807.1 - 1.1e-07 31.5 5.0 0.011 15.5 0.3 3.7 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_4 PF12763.7 KXT01807.1 - 1.9e-05 24.6 3.1 0.092 12.7 0.2 3.2 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 KXT01807.1 - 0.0086 15.9 2.1 0.24 11.3 0.0 2.9 3 0 0 3 3 3 1 EF hand Alpha-amylase PF00128.24 KXT01808.1 - 1.3e-99 334.0 2.1 2.5e-99 333.0 0.1 1.9 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 KXT01808.1 - 0.036 14.2 0.0 0.087 13.0 0.0 1.6 1 0 0 1 1 1 0 Maltogenic Amylase, C-terminal domain adh_short_C2 PF13561.6 KXT01809.1 - 3e-51 174.3 0.0 3.7e-51 174.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXT01809.1 - 2.8e-45 154.2 0.0 3.6e-45 153.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXT01809.1 - 1.1e-09 38.4 0.0 1.7e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 KR domain DFP PF04127.15 KXT01809.1 - 0.0024 17.7 0.9 0.021 14.7 1.1 2.2 2 1 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein THF_DHG_CYH_C PF02882.19 KXT01809.1 - 0.0068 15.7 0.0 0.017 14.5 0.0 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GFO_IDH_MocA PF01408.22 KXT01809.1 - 0.038 14.8 0.0 0.071 13.9 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Pyr_redox_3 PF13738.6 KXT01809.1 - 0.048 12.9 0.1 0.067 12.4 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_lectin_2 PF18647.1 KXT01809.1 - 0.087 13.3 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 Alpha-galactosyl-binding fungal lectin DUF3337 PF11816.8 KXT01810.1 - 6.5e-58 195.4 0.0 1.3e-57 194.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 KXT01810.1 - 1.1e-19 70.3 12.1 3.5e-05 24.5 0.2 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KXT01810.1 - 0.018 14.0 0.3 0.11 11.4 0.0 2.4 4 0 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 KXT01810.1 - 0.1 12.9 0.5 2 8.7 0.1 3.1 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain MFS_1 PF07690.16 KXT01812.1 - 2.8e-22 79.1 27.0 2.8e-22 79.1 27.0 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KXT01812.1 - 3.5e-06 26.5 14.5 0.00026 20.4 3.0 2.5 2 1 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB MIX PF18529.1 KXT01812.1 - 0.19 11.4 0.1 0.34 10.6 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial membrane-anchored proteins PMP1_2 PF08114.11 KXT01812.1 - 0.73 9.6 3.9 21 5.0 0.4 2.8 2 0 0 2 2 2 0 ATPase proteolipid family DcpS PF05652.12 KXT01813.1 - 1.5e-34 119.0 0.0 2.4e-34 118.3 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 KXT01813.1 - 4.6e-32 110.9 0.1 7.2e-32 110.2 0.1 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Dynamitin PF04912.14 KXT01813.1 - 0.032 13.6 0.0 0.035 13.4 0.0 1.1 1 0 0 1 1 1 0 Dynamitin HIT PF01230.23 KXT01813.1 - 0.065 14.0 0.3 0.18 12.6 0.3 1.7 1 0 0 1 1 1 0 HIT domain CTNNBL PF08216.11 KXT01814.1 - 4.4e-37 126.4 0.0 1.5e-36 124.7 0.0 2.0 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear Mo25 PF08569.11 KXT01814.1 - 0.024 14.0 0.6 0.051 12.9 0.6 1.6 1 1 0 1 1 1 0 Mo25-like Ribosomal_S5_C PF03719.15 KXT01814.1 - 0.042 13.3 0.0 0.077 12.5 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S5, C-terminal domain PAH PF02671.21 KXT01814.1 - 0.053 13.7 0.3 8.7 6.6 0.0 3.2 3 0 0 3 3 3 0 Paired amphipathic helix repeat Arm_2 PF04826.13 KXT01814.1 - 0.058 12.9 0.1 0.13 11.7 0.1 1.6 1 0 0 1 1 1 0 Armadillo-like MMS19_C PF12460.8 KXT01814.1 - 0.18 10.9 2.2 0.32 10.0 0.1 2.3 3 0 0 3 3 3 0 RNAPII transcription regulator C-terminal UPF0184 PF03670.13 KXT01814.1 - 0.51 10.8 0.0 0.51 10.8 0.0 3.5 4 1 1 5 5 5 0 Uncharacterised protein family (UPF0184) GDP_Man_Dehyd PF16363.5 KXT01815.1 - 4.9e-54 183.9 0.0 6.3e-54 183.6 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KXT01815.1 - 5.1e-49 166.9 0.0 6.5e-49 166.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXT01815.1 - 7.9e-19 67.7 0.0 2.8e-18 65.9 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KXT01815.1 - 1.9e-14 53.5 0.0 1.1e-12 47.7 0.0 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KXT01815.1 - 1.2e-11 44.2 0.0 1.8e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 KXT01815.1 - 1.6e-10 40.8 0.0 2.9e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXT01815.1 - 1.7e-07 31.4 0.0 3e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 KXT01815.1 - 1.1e-05 24.8 0.0 0.00014 21.1 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein adh_short_C2 PF13561.6 KXT01815.1 - 4.9e-05 23.0 0.0 9.4e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KXT01815.1 - 0.00028 20.8 0.0 0.00045 20.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXT01815.1 - 0.014 14.9 0.0 0.063 12.8 0.0 1.9 2 0 0 2 2 2 0 NmrA-like family TSA PF03249.13 KXT01815.1 - 0.099 11.4 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Type specific antigen UDPG_MGDP_dh_N PF03721.14 KXT01815.1 - 0.14 11.7 0.1 0.26 10.9 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain tRNA_bind PF01588.20 KXT01817.1 - 9.6e-23 80.1 0.1 1.3e-21 76.5 0.0 2.6 2 1 0 2 2 2 1 Putative tRNA binding domain GST_C_2 PF13410.6 KXT01817.1 - 0.00068 19.6 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXT01817.1 - 0.0079 16.4 0.0 0.0079 16.4 0.0 2.7 3 1 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KXT01817.1 - 0.024 14.4 0.0 0.044 13.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Latrophilin PF02354.16 KXT01817.1 - 0.11 11.6 0.5 0.21 10.6 0.5 1.4 1 0 0 1 1 1 0 Latrophilin Cytoplasmic C-terminal region RPN2_C PF18004.1 KXT01817.1 - 6 6.8 17.2 0.79 9.6 12.6 1.8 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain IML1 PF12257.8 KXT01818.1 - 6.2e-84 281.5 0.5 2.1e-83 279.8 0.5 1.8 1 1 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 KXT01818.1 - 1.4e-20 73.1 0.2 2.9e-20 72.1 0.2 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) EamA PF00892.20 KXT01820.1 - 0.0026 17.9 20.2 0.013 15.7 20.2 1.8 1 1 0 1 1 1 1 EamA-like transporter family TMEM234 PF10639.9 KXT01820.1 - 0.084 12.9 4.0 0.11 12.5 4.0 1.2 1 0 0 1 1 1 0 Putative transmembrane family 234 TFIIA_gamma_C PF02751.14 KXT01821.1 - 4.5e-24 84.3 3.3 7e-24 83.7 3.3 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 KXT01821.1 - 2.3e-22 78.7 0.1 3.3e-22 78.2 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain DNA_pol_delta_4 PF04081.13 KXT01822.1 - 1.5e-37 128.9 3.7 1.5e-37 128.9 3.7 2.2 1 1 1 2 2 2 1 DNA polymerase delta, subunit 4 DUF1690 PF07956.11 KXT01822.1 - 0.17 12.3 3.0 0.29 11.5 2.6 1.7 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) TFIID_30kDa PF03540.13 KXT01823.1 - 1.6e-24 85.6 0.2 2.5e-24 85.0 0.2 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit AflR PF08493.10 KXT01823.1 - 0.041 13.3 4.0 0.054 13.0 4.0 1.2 1 0 0 1 1 1 0 Aflatoxin regulatory protein TAF4 PF05236.14 KXT01823.1 - 0.28 10.9 0.0 0.28 10.9 0.0 1.8 2 1 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family GST_N_2 PF13409.6 KXT01824.1 - 1.7e-21 76.2 0.1 6.9e-21 74.3 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXT01824.1 - 2.2e-16 59.6 0.0 1.6e-15 56.8 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXT01824.1 - 2e-08 34.3 0.0 7.5e-08 32.5 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KXT01824.1 - 3.9e-06 27.2 0.2 0.00016 22.0 0.1 2.6 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXT01824.1 - 0.00074 19.7 0.2 0.0024 18.0 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KXT01824.1 - 0.17 12.5 0.0 0.3 11.7 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KXT01825.1 - 1.7e-21 76.2 0.1 6.9e-21 74.3 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXT01825.1 - 2.2e-16 59.6 0.0 1.6e-15 56.8 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXT01825.1 - 2e-08 34.3 0.0 7.5e-08 32.5 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KXT01825.1 - 3.9e-06 27.2 0.2 0.00016 22.0 0.1 2.6 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXT01825.1 - 0.00074 19.7 0.2 0.0024 18.0 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KXT01825.1 - 0.17 12.5 0.0 0.3 11.7 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Fungal_trans PF04082.18 KXT01826.1 - 3.1e-13 49.4 1.3 6e-13 48.4 1.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KXT01826.1 - 2.9e-09 36.9 6.2 0.0002 21.6 0.1 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXT01826.1 - 8.9e-09 35.4 10.5 5.1e-08 33.0 2.3 3.2 3 0 0 3 3 3 2 Zinc-finger double domain Zn_clus PF00172.18 KXT01826.1 - 6.9e-08 32.5 11.1 6.9e-08 32.5 11.1 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_jaz PF12171.8 KXT01826.1 - 0.00016 21.8 1.5 0.26 11.6 0.0 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KXT01826.1 - 0.0021 18.7 15.7 0.03 15.1 1.2 3.5 4 0 0 4 4 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KXT01826.1 - 0.0097 15.9 3.2 1.5 8.9 0.4 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KXT01826.1 - 0.012 16.0 1.2 0.79 10.2 0.4 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type TPR_16 PF13432.6 KXT01826.1 - 0.075 13.7 1.7 0.076 13.7 0.1 1.8 2 0 0 2 2 1 0 Tetratricopeptide repeat zf-C2H2_11 PF16622.5 KXT01826.1 - 0.1 12.3 0.1 1.1 9.1 0.0 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2HE PF16278.5 KXT01826.1 - 0.11 13.0 1.8 8.2 7.0 0.5 2.8 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf_C2H2_ZHX PF18387.1 KXT01826.1 - 3.1 7.5 4.6 7.6 6.3 0.3 2.8 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain Acetyltransf_1 PF00583.25 KXT01827.1 - 2.3e-10 40.7 0.0 3.6e-10 40.1 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXT01827.1 - 4e-10 39.7 0.0 7e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXT01827.1 - 7.8e-08 32.6 0.0 1.4e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KXT01827.1 - 4.5e-07 30.0 0.2 0.00017 21.7 0.0 2.6 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXT01827.1 - 0.00041 20.3 0.0 0.0008 19.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KXT01827.1 - 0.0026 17.8 0.0 0.0056 16.8 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase CDC27 PF09507.10 KXT01827.1 - 0.013 14.9 0.0 0.015 14.7 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Cyclin_N PF00134.23 KXT01828.1 - 1.1e-11 44.6 0.8 1.9e-11 43.8 0.2 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain NAD_binding_9 PF13454.6 KXT01828.1 - 0.053 13.5 0.5 0.11 12.5 0.5 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Cyclin_C_2 PF16899.5 KXT01828.1 - 0.078 13.4 2.1 0.15 12.5 0.3 2.4 3 1 0 3 3 3 0 Cyclin C-terminal domain TFIIB PF00382.19 KXT01828.1 - 0.082 13.0 0.4 0.22 11.6 0.4 1.8 1 1 0 1 1 1 0 Transcription factor TFIIB repeat Sugar_tr PF00083.24 KXT01829.1 - 7.2e-91 305.3 19.1 8.3e-91 305.1 19.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXT01829.1 - 1.3e-24 86.8 39.4 2.7e-18 66.0 12.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KXT01829.1 - 0.023 13.0 14.7 0.41 8.9 0.1 3.2 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family FAD_binding_4 PF01565.23 KXT01831.1 - 2.5e-29 101.8 0.6 4.2e-29 101.1 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain UPF0561 PF10573.9 KXT01832.1 - 0.014 15.5 4.6 0.014 15.5 4.6 2.1 1 1 1 2 2 2 0 Uncharacterised protein family UPF0561 adh_short_C2 PF13561.6 KXT01834.1 - 1.6e-57 194.8 3.1 2e-57 194.4 3.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXT01834.1 - 1.2e-43 148.8 0.5 1.6e-43 148.5 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXT01834.1 - 1.6e-08 34.7 1.0 2.5e-08 34.1 1.0 1.3 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 KXT01834.1 - 0.0023 17.3 0.2 0.0068 15.8 0.1 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 KXT01834.1 - 0.11 12.0 0.1 0.24 10.8 0.1 1.6 1 1 1 2 2 2 0 NAD dependent epimerase/dehydratase family DIOX_N PF14226.6 KXT01843.1 - 8e-05 23.4 0.1 9.3e-05 23.2 0.1 1.1 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal DUF5343 PF17278.2 KXT01843.1 - 0.054 13.6 0.0 0.066 13.3 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5343) uDENN PF03456.18 KXT01844.1 - 0.23 12.3 2.0 2.1 9.1 0.1 2.3 2 0 0 2 2 2 0 uDENN domain Cofilin_ADF PF00241.20 KXT01845.1 - 6.7e-40 135.7 0.1 7.5e-40 135.5 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Fumerase PF05681.14 KXT01845.1 - 0.073 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Fumarate hydratase (Fumerase) Blt1 PF12754.7 KXT01846.1 - 6.1e-32 111.0 1.2 1.1e-31 110.2 1.2 1.4 1 0 0 1 1 1 1 Blt1 N-terminal domain Blt1_C PF17183.4 KXT01846.1 - 3.7e-17 61.7 0.4 6.9e-17 60.8 0.4 1.5 1 0 0 1 1 1 1 Get5 carboxyl domain ubiquitin PF00240.23 KXT01846.1 - 1.8e-06 27.6 0.4 3.1e-06 26.9 0.4 1.3 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_5 PF18037.1 KXT01846.1 - 2e-05 24.9 0.4 4.3e-05 23.8 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 KXT01846.1 - 3.5e-05 23.6 0.3 6.4e-05 22.7 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like SAF PF08666.12 KXT01846.1 - 0.083 13.5 0.0 0.19 12.4 0.0 1.6 1 0 0 1 1 1 0 SAF domain Na_H_Exchanger PF00999.21 KXT01847.1 - 3e-75 253.4 37.2 3.8e-75 253.1 37.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PepSY_TM PF03929.16 KXT01847.1 - 0.019 14.7 0.4 0.019 14.7 0.4 2.3 3 0 0 3 3 3 0 PepSY-associated TM region DUF3169 PF11368.8 KXT01847.1 - 0.02 14.4 0.2 0.02 14.4 0.2 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3169) Kelch_6 PF13964.6 KXT01847.1 - 0.15 12.4 0.0 0.36 11.2 0.0 1.6 1 0 0 1 1 1 0 Kelch motif Epimerase PF01370.21 KXT01848.1 - 0.00069 19.2 0.0 0.00086 18.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KXT01848.1 - 0.0011 18.2 0.0 0.002 17.3 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 KXT01848.1 - 0.0019 17.3 0.0 0.17 10.9 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KXT01848.1 - 0.003 17.5 0.0 0.037 13.9 0.0 2.1 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KXT01848.1 - 0.047 12.8 0.0 0.068 12.3 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein SAS-6_N PF16531.5 KXT01848.1 - 0.12 13.0 0.0 0.2 12.3 0.0 1.5 1 1 0 1 1 1 0 Centriolar protein SAS N-terminal FAD_binding_3 PF01494.19 KXT01850.1 - 7.6e-81 272.1 0.0 1.4e-80 271.2 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain Phe_hydrox_dim PF07976.12 KXT01850.1 - 1.6e-27 96.6 0.0 2.9e-27 95.7 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 KXT01850.1 - 3.3e-07 29.8 0.3 3.7e-06 26.4 0.0 2.7 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXT01850.1 - 1.9e-06 27.7 0.0 2.5e-05 24.0 0.0 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXT01850.1 - 1.1e-05 25.9 0.0 0.00023 21.7 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXT01850.1 - 0.00016 20.5 0.0 0.00029 19.7 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.12 KXT01850.1 - 0.00028 20.1 0.1 0.00043 19.4 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KXT01850.1 - 0.00052 20.2 0.6 0.0041 17.3 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Inj_translocase PF16928.5 KXT01850.1 - 0.00096 18.7 0.1 0.0017 17.9 0.1 1.3 1 0 0 1 1 1 1 DNA/protein translocase of phage P22 injectosome AlaDh_PNT_C PF01262.21 KXT01850.1 - 0.0021 17.4 0.0 0.0057 16.0 0.0 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 KXT01850.1 - 0.0028 16.8 0.0 0.0028 16.8 0.0 2.1 3 0 0 3 3 2 1 FAD binding domain Thi4 PF01946.17 KXT01850.1 - 0.0056 15.9 0.8 0.0085 15.4 0.0 1.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 KXT01850.1 - 0.0063 15.8 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXT01850.1 - 0.0069 15.5 0.0 0.02 14.0 0.0 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KXT01850.1 - 0.018 14.4 0.1 0.039 13.3 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.18 KXT01850.1 - 0.042 14.1 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 TrkA-N domain XdhC_C PF13478.6 KXT01850.1 - 0.062 13.8 0.0 0.15 12.6 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain Shikimate_DH PF01488.20 KXT01850.1 - 0.2 11.7 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Gtr1_RagA PF04670.12 KXT01851.1 - 2.5e-86 288.8 0.1 3e-86 288.5 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KXT01851.1 - 1.3e-09 38.3 0.0 3.4e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXT01851.1 - 1.7e-09 37.4 0.1 5.9e-09 35.6 0.0 1.8 1 1 1 2 2 2 1 ADP-ribosylation factor family Ras PF00071.22 KXT01851.1 - 1.1e-08 34.9 0.0 2e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KXT01851.1 - 8.4e-08 32.3 0.0 2.6e-07 30.7 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase G-alpha PF00503.20 KXT01851.1 - 0.0008 18.7 3.9 0.28 10.3 0.1 3.0 2 1 1 3 3 3 2 G-protein alpha subunit DUF815 PF05673.13 KXT01851.1 - 0.0027 16.9 0.0 0.0051 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ABC_tran PF00005.27 KXT01851.1 - 0.0037 17.8 0.1 0.0081 16.7 0.0 1.8 2 1 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 KXT01851.1 - 0.0041 17.0 0.2 0.11 12.3 0.0 2.6 3 0 0 3 3 3 1 RsgA GTPase AAA_29 PF13555.6 KXT01851.1 - 0.0093 15.7 0.8 0.16 11.7 0.0 2.7 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KXT01851.1 - 0.018 15.4 0.0 0.03 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 KXT01851.1 - 0.021 14.2 0.0 0.038 13.4 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_10 PF12846.7 KXT01851.1 - 0.093 11.6 0.8 0.22 10.4 0.1 2.0 2 1 0 2 2 2 0 AAA-like domain DUF3697 PF12478.8 KXT01851.1 - 0.12 12.5 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-associated protein 2 Spc7 PF08317.11 KXT01852.1 - 9.9e-07 27.9 132.8 0.00035 19.6 14.3 5.6 1 1 5 6 6 6 5 Spc7 kinetochore protein Filament PF00038.21 KXT01852.1 - 2.3e-06 27.5 114.4 0.038 13.6 46.2 5.3 1 1 3 4 4 4 4 Intermediate filament protein MscS_porin PF12795.7 KXT01852.1 - 9.2e-05 22.1 130.7 0.049 13.2 33.6 5.2 1 1 3 4 4 4 2 Mechanosensitive ion channel porin domain GAS PF13851.6 KXT01852.1 - 0.00023 20.6 131.6 0.078 12.3 12.4 6.4 1 1 7 8 8 8 4 Growth-arrest specific micro-tubule binding HMMR_N PF15905.5 KXT01852.1 - 0.0005 19.6 125.8 0.024 14.1 25.6 4.6 1 1 3 4 4 4 3 Hyaluronan mediated motility receptor N-terminal Rootletin PF15035.6 KXT01852.1 - 0.0014 18.7 23.9 0.0014 18.7 23.9 5.1 1 1 2 3 3 2 1 Ciliary rootlet component, centrosome cohesion Lebercilin PF15619.6 KXT01852.1 - 0.0027 17.4 13.1 0.0027 17.4 13.1 6.7 1 1 5 6 6 5 2 Ciliary protein causing Leber congenital amaurosis disease DUF3584 PF12128.8 KXT01852.1 - 0.0033 15.0 132.0 0.0015 16.1 62.9 4.0 1 1 3 4 4 4 2 Protein of unknown function (DUF3584) BRE1 PF08647.11 KXT01852.1 - 0.0053 16.8 17.2 0.0053 16.8 17.2 8.7 3 2 6 9 9 8 2 BRE1 E3 ubiquitin ligase APG6_N PF17675.1 KXT01852.1 - 0.0089 16.6 159.5 0.075 13.6 20.2 7.8 1 1 4 5 5 4 2 Apg6 coiled-coil region ABC_tran_CTD PF16326.5 KXT01852.1 - 0.019 15.2 10.5 0.019 15.2 10.5 11.1 2 2 8 10 10 8 0 ABC transporter C-terminal domain ATG16 PF08614.11 KXT01852.1 - 0.032 14.4 141.7 0.98 9.6 13.9 6.0 1 1 5 6 6 6 0 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 KXT01852.1 - 0.1 11.9 128.2 0.67 9.2 23.1 5.1 1 1 4 5 5 5 0 Domain of unknown function (DUF4407) Tup_N PF08581.10 KXT01852.1 - 0.23 11.8 82.0 0.37 11.1 3.7 10.1 2 1 8 11 11 11 0 Tup N-terminal Limkain-b1 PF11608.8 KXT01852.1 - 0.3 11.2 2.4 0.48 10.5 0.6 2.4 2 0 0 2 2 2 0 Limkain b1 Rab5-bind PF09311.11 KXT01852.1 - 0.86 8.9 106.8 9.7 5.5 13.4 4.9 1 1 1 3 3 3 0 Rabaptin-like protein Golgin_A5 PF09787.9 KXT01852.1 - 1.2 8.5 112.8 0.38 10.2 13.2 5.3 1 1 4 5 5 5 0 Golgin subfamily A member 5 Fez1 PF06818.15 KXT01852.1 - 5.2 7.5 117.2 0.2 12.1 21.1 5.4 1 1 3 4 4 3 0 Fez1 TPR_MLP1_2 PF07926.12 KXT01852.1 - 7.4 6.6 161.7 1.4 9.0 24.8 7.3 1 1 7 8 8 8 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 KXT01853.1 - 9.9e-07 27.9 132.8 0.00035 19.6 14.3 5.6 1 1 5 6 6 6 5 Spc7 kinetochore protein Filament PF00038.21 KXT01853.1 - 2.3e-06 27.5 114.4 0.038 13.6 46.2 5.3 1 1 3 4 4 4 4 Intermediate filament protein MscS_porin PF12795.7 KXT01853.1 - 9.2e-05 22.1 130.7 0.049 13.2 33.6 5.2 1 1 3 4 4 4 2 Mechanosensitive ion channel porin domain GAS PF13851.6 KXT01853.1 - 0.00023 20.6 131.6 0.078 12.3 12.4 6.4 1 1 7 8 8 8 4 Growth-arrest specific micro-tubule binding HMMR_N PF15905.5 KXT01853.1 - 0.0005 19.6 125.8 0.024 14.1 25.6 4.6 1 1 3 4 4 4 3 Hyaluronan mediated motility receptor N-terminal Rootletin PF15035.6 KXT01853.1 - 0.0014 18.7 23.9 0.0014 18.7 23.9 5.1 1 1 2 3 3 2 1 Ciliary rootlet component, centrosome cohesion Lebercilin PF15619.6 KXT01853.1 - 0.0027 17.4 13.1 0.0027 17.4 13.1 6.7 1 1 5 6 6 5 2 Ciliary protein causing Leber congenital amaurosis disease DUF3584 PF12128.8 KXT01853.1 - 0.0033 15.0 132.0 0.0015 16.1 62.9 4.0 1 1 3 4 4 4 2 Protein of unknown function (DUF3584) BRE1 PF08647.11 KXT01853.1 - 0.0053 16.8 17.2 0.0053 16.8 17.2 8.7 3 2 6 9 9 8 2 BRE1 E3 ubiquitin ligase APG6_N PF17675.1 KXT01853.1 - 0.0089 16.6 159.5 0.075 13.6 20.2 7.8 1 1 4 5 5 4 2 Apg6 coiled-coil region ABC_tran_CTD PF16326.5 KXT01853.1 - 0.019 15.2 10.5 0.019 15.2 10.5 11.1 2 2 8 10 10 8 0 ABC transporter C-terminal domain ATG16 PF08614.11 KXT01853.1 - 0.032 14.4 141.7 0.98 9.6 13.9 6.0 1 1 5 6 6 6 0 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 KXT01853.1 - 0.1 11.9 128.2 0.67 9.2 23.1 5.1 1 1 4 5 5 5 0 Domain of unknown function (DUF4407) Tup_N PF08581.10 KXT01853.1 - 0.23 11.8 82.0 0.37 11.1 3.7 10.1 2 1 8 11 11 11 0 Tup N-terminal Limkain-b1 PF11608.8 KXT01853.1 - 0.3 11.2 2.4 0.48 10.5 0.6 2.4 2 0 0 2 2 2 0 Limkain b1 Rab5-bind PF09311.11 KXT01853.1 - 0.86 8.9 106.8 9.7 5.5 13.4 4.9 1 1 1 3 3 3 0 Rabaptin-like protein Golgin_A5 PF09787.9 KXT01853.1 - 1.2 8.5 112.8 0.38 10.2 13.2 5.3 1 1 4 5 5 5 0 Golgin subfamily A member 5 Fez1 PF06818.15 KXT01853.1 - 5.2 7.5 117.2 0.2 12.1 21.1 5.4 1 1 3 4 4 3 0 Fez1 TPR_MLP1_2 PF07926.12 KXT01853.1 - 7.4 6.6 161.7 1.4 9.0 24.8 7.3 1 1 7 8 8 8 0 TPR/MLP1/MLP2-like protein IDO PF01231.18 KXT01854.1 - 8.9e-144 479.5 0.0 1.1e-143 479.2 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase HsbA PF12296.8 KXT01856.1 - 1.5e-18 67.4 0.2 2.2e-18 66.8 0.2 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Pro_isomerase PF00160.21 KXT01857.1 - 2.2e-39 135.3 0.0 4.3e-39 134.3 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Fungal_trans PF04082.18 KXT01858.1 - 1.8e-07 30.4 0.1 3.1e-07 29.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT01858.1 - 2.1e-06 27.8 11.1 3.7e-06 27.0 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXT01859.1 - 1.8e-07 30.4 0.1 3.1e-07 29.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT01859.1 - 2.1e-06 27.8 11.1 3.7e-06 27.0 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXT01860.1 - 1.8e-07 30.4 0.1 3.1e-07 29.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT01860.1 - 2.1e-06 27.8 11.1 3.7e-06 27.0 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain THOC2_N PF16134.5 KXT01861.1 - 5.6e-209 695.9 0.0 9e-209 695.2 0.0 1.3 1 0 0 1 1 1 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 KXT01861.1 - 4.3e-99 331.5 1.7 7.6e-99 330.7 1.7 1.4 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 KXT01861.1 - 7.4e-26 90.0 0.0 3.6e-25 87.8 0.0 2.3 2 0 0 2 2 2 1 Transcription- and export-related complex subunit DUF2487 PF10673.9 KXT01861.1 - 0.18 11.8 0.3 0.51 10.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2487) CorA PF01544.18 KXT01862.1 - 2.3e-11 43.6 0.0 4.7e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Acetyltransf_7 PF13508.7 KXT01862.1 - 2.1e-05 24.9 0.2 4.5e-05 23.8 0.2 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXT01862.1 - 0.00028 21.1 0.0 0.00059 20.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXT01862.1 - 0.00054 19.9 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXT01862.1 - 0.0036 17.2 0.0 0.0074 16.2 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein VMA21 PF09446.10 KXT01862.1 - 0.13 12.3 2.7 0.34 11.0 2.7 1.6 1 0 0 1 1 1 0 VMA21-like domain NAD_binding_2 PF03446.15 KXT01863.1 - 3.6e-33 115.0 0.1 5e-33 114.5 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KXT01863.1 - 5.1e-26 91.3 0.0 8.6e-26 90.6 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.19 KXT01863.1 - 1.1e-07 31.3 0.0 2e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KXT01863.1 - 9.1e-06 26.2 0.1 2.7e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.9 KXT01863.1 - 0.0013 18.6 0.0 0.0027 17.5 0.0 1.6 1 0 0 1 1 1 1 Rossmann-like domain 3HCDH_N PF02737.18 KXT01863.1 - 0.0024 17.8 0.2 0.0081 16.1 0.0 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.12 KXT01863.1 - 0.0025 17.4 0.1 0.005 16.4 0.1 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 KXT01863.1 - 0.043 14.1 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 KXT01863.1 - 0.059 12.9 0.0 0.17 11.4 0.0 1.8 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GARS_A PF01071.19 KXT01864.1 - 1.7e-79 266.1 0.0 2.6e-79 265.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 KXT01864.1 - 1.6e-33 115.3 0.1 3.5e-33 114.2 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 KXT01864.1 - 9.7e-29 99.5 1.2 2.7e-28 98.1 1.2 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain ATP-grasp PF02222.22 KXT01864.1 - 2.2e-06 27.4 0.0 3.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 KXT01864.1 - 6.7e-05 22.5 0.0 0.00011 21.8 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.14 KXT01864.1 - 0.00012 22.1 0.0 0.00022 21.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 KXT01864.1 - 0.012 15.2 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain RimK PF08443.11 KXT01864.1 - 0.013 15.1 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 RimK-like ATP-grasp domain Fungal_trans PF04082.18 KXT01865.1 - 8.6e-16 57.8 0.1 1.5e-15 57.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT01865.1 - 0.00089 19.3 10.8 0.0019 18.3 10.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_28 PF00295.17 KXT01866.1 - 3.6e-29 101.9 3.8 5.1e-29 101.4 3.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.7 KXT01866.1 - 1.4e-10 41.4 9.2 1e-09 38.6 4.4 3.2 1 1 1 2 2 2 1 Pectate lyase superfamily protein FAD_binding_3 PF01494.19 KXT01867.1 - 0.001 18.4 0.0 0.0012 18.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Glyco_hydro_71 PF03659.14 KXT01869.1 - 2.5e-141 470.8 6.2 2.5e-141 470.8 6.2 1.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 71 Polysacc_deac_1 PF01522.21 KXT01871.1 - 6e-17 61.7 0.0 1.2e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 KXT01871.1 - 3.1e-05 23.7 0.1 0.00012 21.9 0.0 2.1 2 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2334) Oxidored_FMN PF00724.20 KXT01872.1 - 1.2e-89 300.9 0.0 7.3e-89 298.4 0.0 1.8 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family F-box-like PF12937.7 KXT01873.1 - 3.4e-08 33.3 3.8 3.4e-08 33.3 3.8 2.5 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KXT01873.1 - 0.00069 19.4 0.9 0.027 14.4 0.9 3.0 1 1 0 1 1 1 1 F-box domain DUF3847 PF12958.7 KXT01874.1 - 0.042 14.0 8.7 0.075 13.2 0.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3847) HlyE PF06109.13 KXT01874.1 - 0.044 13.1 0.2 0.084 12.2 0.2 1.4 1 0 0 1 1 1 0 Haemolysin E (HlyE) Lip_A_acyltrans PF03279.13 KXT01874.1 - 0.052 12.7 0.3 0.24 10.5 0.3 1.9 1 1 0 1 1 1 0 Bacterial lipid A biosynthesis acyltransferase SlyX PF04102.12 KXT01874.1 - 5 7.8 7.7 2.7 8.7 0.6 3.0 2 1 1 3 3 3 0 SlyX DivIC PF04977.15 KXT01874.1 - 6.6 6.6 7.0 8.6 6.2 1.4 2.7 1 1 1 2 2 2 0 Septum formation initiator UreF PF01730.16 KXT01875.1 - 2.1e-23 83.3 0.2 2.8e-23 83.0 0.2 1.1 1 0 0 1 1 1 1 UreF MOSC PF03473.17 KXT01877.1 - 7.3e-24 84.3 0.0 1.2e-23 83.6 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KXT01877.1 - 2.4e-17 62.9 0.0 4.1e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Transp_cyt_pur PF02133.15 KXT01878.1 - 1.8e-11 43.5 27.2 6.3e-11 41.7 27.2 1.7 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MINDY_DUB PF04424.13 KXT01879.1 - 2.9e-25 88.6 0.0 5.3e-25 87.7 0.0 1.4 1 0 0 1 1 1 1 MINDY deubiquitinase Amidase PF01425.21 KXT01880.1 - 9.2e-106 354.5 0.0 1.1e-105 354.2 0.0 1.1 1 0 0 1 1 1 1 Amidase UPF0180 PF03698.13 KXT01880.1 - 0.081 13.1 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) DnaJ_C PF01556.18 KXT01881.1 - 1.2e-34 119.5 0.6 1.6e-34 119.2 0.6 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KXT01881.1 - 1.4e-24 86.0 1.5 2.9e-24 84.9 1.5 1.6 1 0 0 1 1 1 1 DnaJ domain FUN14 PF04930.15 KXT01882.1 - 9.2e-07 29.2 1.5 9.2e-07 29.2 1.5 1.6 2 0 0 2 2 2 1 FUN14 family Pyr_redox PF00070.27 KXT01883.1 - 0.017 15.7 0.0 0.025 15.1 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXT01883.1 - 0.023 14.9 0.0 0.034 14.4 0.0 1.4 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXT01883.1 - 0.029 13.6 0.0 0.033 13.4 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DegQ PF08181.11 KXT01884.1 - 0.13 12.4 0.1 0.66 10.1 0.1 2.2 2 0 0 2 2 2 0 DegQ (SacQ) family DUF3228 PF11539.8 KXT01884.1 - 0.14 11.7 0.1 0.27 10.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3228) F-box PF00646.33 KXT01885.1 - 9.1e-06 25.4 0.1 1.7e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXT01885.1 - 0.00011 22.0 0.1 0.00029 20.7 0.1 1.7 1 0 0 1 1 1 1 F-box-like FAD_binding_3 PF01494.19 KXT01886.1 - 1.8e-17 63.6 0.3 2.7e-16 59.7 0.3 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXT01886.1 - 2.3e-09 37.3 8.8 1.3e-06 28.3 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KXT01886.1 - 5.4e-07 29.0 0.7 1.1e-06 28.0 0.7 1.4 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KXT01886.1 - 1.8e-06 27.4 0.6 0.014 14.6 0.5 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXT01886.1 - 0.00017 21.8 1.3 0.00049 20.3 1.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KXT01886.1 - 0.00037 21.0 0.9 0.17 12.4 1.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXT01886.1 - 0.0012 18.0 5.6 0.01 14.9 5.0 2.1 2 0 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.24 KXT01886.1 - 0.0017 17.8 3.2 0.088 12.1 0.1 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase HI0933_like PF03486.14 KXT01886.1 - 0.0017 17.1 3.1 0.096 11.4 1.6 2.1 2 0 0 2 2 2 2 HI0933-like protein GIDA PF01134.22 KXT01886.1 - 0.0077 15.4 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A SE PF08491.10 KXT01886.1 - 0.065 12.3 0.0 1.6 7.7 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox_3 PF13738.6 KXT01886.1 - 0.083 12.1 2.1 3 7.0 2.6 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Rossmann-like PF10727.9 KXT01886.1 - 0.11 12.4 0.4 0.5 10.2 0.3 2.0 2 0 0 2 2 2 0 Rossmann-like domain 3HCDH_N PF02737.18 KXT01886.1 - 0.13 12.2 2.1 0.24 11.3 2.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 KXT01886.1 - 1.3 8.3 5.6 1.9 7.8 5.6 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXT01886.1 - 4.5 7.2 7.9 7.1 6.6 0.1 2.6 3 0 0 3 3 2 0 FAD-NAD(P)-binding MFS_2 PF13347.6 KXT01887.1 - 8.7e-10 37.7 22.6 2.2e-09 36.4 7.2 3.1 4 0 0 4 4 4 2 MFS/sugar transport protein MFS_1 PF07690.16 KXT01887.1 - 3.4e-08 32.8 14.8 3.4e-08 32.8 14.8 2.7 3 1 0 3 3 3 2 Major Facilitator Superfamily AIRS_C PF02769.22 KXT01888.1 - 6.5e-33 114.1 0.4 1.3e-32 113.1 0.4 1.4 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 KXT01888.1 - 7.1e-13 49.0 0.5 2.5e-12 47.3 0.5 2.0 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain GHMP_kinases_N PF00288.26 KXT01888.1 - 4.8e-10 39.5 0.1 4.8e-10 39.5 0.1 2.2 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KXT01888.1 - 1.8e-05 25.0 0.0 5.1e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal Cwf_Cwc_15 PF04889.12 KXT01889.1 - 0.17 11.6 2.0 0.23 11.2 2.0 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF3245 PF11595.8 KXT01889.1 - 0.65 10.5 3.0 16 6.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) PBP1_TM PF14812.6 KXT01889.1 - 1.3 9.4 4.9 9.6 6.7 0.3 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal INCENP_ARK-bind PF03941.15 KXT01889.1 - 5.5 7.0 8.2 8.4 6.4 0.5 2.2 2 0 0 2 2 2 0 Inner centromere protein, ARK binding region Cwf_Cwc_15 PF04889.12 KXT01893.1 - 2.2 8.0 12.1 0.25 11.0 1.2 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Cwf_Cwc_15 PF04889.12 KXT01894.1 - 0.17 11.6 2.0 0.23 11.2 2.0 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF3245 PF11595.8 KXT01894.1 - 0.65 10.5 3.0 16 6.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) PBP1_TM PF14812.6 KXT01894.1 - 1.3 9.4 4.9 9.6 6.7 0.3 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal INCENP_ARK-bind PF03941.15 KXT01894.1 - 5.5 7.0 8.2 8.4 6.4 0.5 2.2 2 0 0 2 2 2 0 Inner centromere protein, ARK binding region Cwf_Cwc_15 PF04889.12 KXT01895.1 - 3.5 7.3 12.6 0.27 10.9 1.2 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein ECH_1 PF00378.20 KXT01896.1 - 1.8e-28 99.5 0.0 4.7e-26 91.6 0.0 2.3 2 1 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXT01896.1 - 5.5e-11 42.5 0.0 8.4e-07 28.8 0.0 2.5 2 1 0 2 2 2 2 Enoyl-CoA hydratase/isomerase NPP1 PF05630.11 KXT01897.1 - 1.3e-39 136.3 0.0 1.7e-39 136.0 0.0 1.1 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Fungal_trans PF04082.18 KXT01898.1 - 2e-37 128.7 2.1 3.1e-37 128.1 2.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KXT01898.1 - 1.2e-07 31.8 11.8 0.00064 20.0 1.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXT01898.1 - 0.0003 21.4 10.7 0.078 13.9 1.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger AA_permease PF00324.21 KXT01899.1 - 1.4e-16 60.2 2.4 1.5e-16 60.0 2.4 1.0 1 0 0 1 1 1 1 Amino acid permease Peroxin-3 PF04882.12 KXT01900.1 - 2.1e-166 554.6 0.5 2.9e-166 554.1 0.5 1.2 1 0 0 1 1 1 1 Peroxin-3 ALP_N PF17989.1 KXT01900.1 - 0.057 13.6 0.1 0.18 12.0 0.1 1.9 1 1 1 2 2 2 0 Actin like proteins N terminal domain Tugs PF17840.1 KXT01900.1 - 4.5 7.5 6.0 0.98 9.7 1.5 2.3 2 0 0 2 2 2 0 Tethering Ubl4a to BAGS domain Aminotran_5 PF00266.19 KXT01901.1 - 3.1e-05 23.1 0.0 5.6e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V ECR1_N PF14382.6 KXT01910.1 - 1.1e-12 47.5 0.1 2.6e-12 46.3 0.1 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 KXT01910.1 - 0.00011 22.5 0.1 0.00021 21.6 0.1 1.4 1 0 0 1 1 1 1 KH domain Sugar_tr PF00083.24 KXT01911.1 - 2.5e-80 270.5 26.4 3e-80 270.3 26.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXT01911.1 - 1.3e-17 63.8 27.9 1.3e-17 63.8 27.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Thg1C PF14413.6 KXT01912.1 - 1.1e-50 170.9 0.8 1.5e-50 170.4 0.8 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.12 KXT01912.1 - 4.4e-49 165.7 0.0 6.6e-49 165.1 0.0 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase MFS_1 PF07690.16 KXT01913.1 - 1.9e-27 96.1 18.3 1.9e-27 96.1 18.3 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXT01913.1 - 2.6e-09 36.5 1.8 2.6e-09 36.5 1.8 3.2 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 KXT01913.1 - 0.0025 16.3 1.5 0.0044 15.5 1.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KXT01914.1 - 3.6e-27 95.2 17.1 3.6e-27 95.2 17.1 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXT01914.1 - 3.2e-08 32.9 4.6 3.2e-08 32.9 4.6 3.2 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 KXT01914.1 - 0.003 16.1 1.6 0.0052 15.2 1.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Ndufs5 PF10200.9 KXT01914.1 - 0.21 11.9 0.0 0.36 11.1 0.0 1.3 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Arrestin_N PF00339.29 KXT01916.1 - 6.3e-16 58.7 0.0 2.7e-15 56.7 0.0 1.9 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Glyco_trans_2_3 PF13632.6 KXT01918.1 - 2.3e-51 174.5 5.9 8.2e-51 172.7 5.9 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KXT01918.1 - 3.6e-06 26.9 0.0 3.7e-05 23.6 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KXT01918.1 - 3.6e-05 23.3 0.6 8.1e-05 22.2 0.1 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 KXT01918.1 - 0.00044 20.2 0.1 0.00098 19.1 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Pkinase PF00069.25 KXT01919.1 - 9.3e-21 74.4 0.0 2.4e-18 66.4 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXT01919.1 - 3.8e-11 42.8 0.0 2.3e-10 40.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase G2BR PF18442.1 KXT01919.1 - 0.074 12.7 0.2 0.35 10.6 0.2 2.2 1 0 0 1 1 1 0 E3 gp78 Ube2g2-binding region (G2BR) Pkinase PF00069.25 KXT01920.1 - 9.3e-21 74.4 0.0 2.4e-18 66.4 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXT01920.1 - 3.8e-11 42.8 0.0 2.3e-10 40.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase G2BR PF18442.1 KXT01920.1 - 0.074 12.7 0.2 0.35 10.6 0.2 2.2 1 0 0 1 1 1 0 E3 gp78 Ube2g2-binding region (G2BR) zf-C2H2_jaz PF12171.8 KXT01921.1 - 1.3e-09 38.1 0.5 1.9e-09 37.5 0.5 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXT01921.1 - 4.1e-07 30.2 0.5 7.3e-07 29.4 0.5 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-DBF PF07535.12 KXT01921.1 - 0.034 14.3 0.1 0.063 13.4 0.1 1.3 1 0 0 1 1 1 0 DBF zinc finger zf-U1 PF06220.12 KXT01921.1 - 0.091 12.5 0.1 0.24 11.2 0.1 1.7 1 0 0 1 1 1 0 U1 zinc finger zf-C2H2_2 PF12756.7 KXT01921.1 - 0.12 12.7 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 KXT01921.1 - 0.17 12.4 0.5 0.29 11.7 0.5 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type Fzo_mitofusin PF04799.13 KXT01921.1 - 0.27 10.8 2.3 0.39 10.3 2.3 1.2 1 0 0 1 1 1 0 fzo-like conserved region DUF1764 PF08576.10 KXT01921.1 - 5.2 8.0 11.3 2.7 8.9 7.5 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) DUF4407 PF14362.6 KXT01921.1 - 8.5 5.6 10.7 12 5.1 10.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MRJP PF03022.16 KXT01923.1 - 2.4e-13 50.1 0.0 3.2e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Major royal jelly protein SGL PF08450.12 KXT01923.1 - 1.2e-08 34.9 0.1 6.8e-05 22.6 0.1 3.2 1 1 3 4 4 4 2 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 KXT01923.1 - 0.13 12.3 0.2 9.4 6.5 0.1 3.3 4 0 0 4 4 4 0 NHL repeat PD40 PF07676.12 KXT01923.1 - 0.17 11.9 0.9 0.44 10.6 0.1 2.2 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat OTU PF02338.19 KXT01924.1 - 4.6e-21 75.6 0.0 1.3e-20 74.2 0.0 1.8 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KXT01924.1 - 0.023 14.2 0.0 2.5 7.5 0.0 2.4 2 0 0 2 2 2 0 Peptidase C65 Otubain Phage_Mu_F PF04233.14 KXT01924.1 - 0.023 15.4 1.1 0.023 15.4 1.1 2.4 3 0 0 3 3 3 0 Phage Mu protein F like protein DUF4407 PF14362.6 KXT01924.1 - 8.4 5.6 19.9 12 5.1 19.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) His_Phos_1 PF00300.22 KXT01927.1 - 7.2e-05 22.6 2.2 0.21 11.2 0.1 3.3 2 2 1 3 3 3 2 Histidine phosphatase superfamily (branch 1) 5_nucleotid_C PF02872.18 KXT01928.1 - 9.8e-42 142.8 0.0 2.3e-41 141.7 0.0 1.6 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KXT01928.1 - 2.3e-07 31.5 0.0 3.2e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FrhB_FdhB_N PF04422.13 KXT01928.1 - 0.041 14.0 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term Homeobox_KN PF05920.11 KXT01929.1 - 1.9e-16 59.7 1.2 4.6e-16 58.4 0.7 2.1 2 0 0 2 2 2 1 Homeobox KN domain HTH_Tnp_Tc5 PF03221.16 KXT01929.1 - 1e-06 28.6 0.1 4.5e-06 26.6 0.1 2.2 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Homeodomain PF00046.29 KXT01929.1 - 3.3e-05 23.6 0.1 7.9e-05 22.4 0.1 1.6 1 0 0 1 1 1 1 Homeodomain zf-C2H2_4 PF13894.6 KXT01929.1 - 0.0022 18.7 2.2 0.0022 18.7 2.2 5.8 6 0 0 6 6 6 1 C2H2-type zinc finger zf-C2H2 PF00096.26 KXT01929.1 - 0.016 15.6 23.7 0.25 11.9 2.6 5.1 4 0 0 4 4 4 0 Zinc finger, C2H2 type Zn_clus PF00172.18 KXT01929.1 - 0.29 11.3 9.7 0.034 14.3 4.8 2.0 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_2 PF12756.7 KXT01929.1 - 1.9 8.9 12.0 58 4.1 0.1 3.7 1 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) Med21 PF11221.8 KXT01930.1 - 0.065 13.5 0.3 0.065 13.5 0.3 2.7 2 1 0 2 2 2 0 Subunit 21 of Mediator complex KfrA_N PF11740.8 KXT01930.1 - 0.14 12.8 0.1 0.14 12.8 0.1 2.2 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term PHD PF00628.29 KXT01931.1 - 2e-05 24.4 6.1 3.6e-05 23.6 6.1 1.4 1 0 0 1 1 1 1 PHD-finger PHD_Oberon PF07227.11 KXT01931.1 - 6.2e-05 22.9 0.7 0.0001 22.2 0.7 1.2 1 0 0 1 1 1 1 PHD - plant homeodomain finger protein eIF3_subunit PF08597.10 KXT01931.1 - 0.059 13.3 0.6 0.088 12.7 0.6 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit BUD22 PF09073.10 KXT01931.1 - 0.068 12.5 4.0 0.091 12.1 4.0 1.2 1 0 0 1 1 1 0 BUD22 zf-HC5HC2H PF13771.6 KXT01931.1 - 0.071 13.4 0.7 0.13 12.5 0.7 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain SOG2 PF10428.9 KXT01931.1 - 0.41 9.8 6.2 0.54 9.4 6.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF908 PF06012.12 KXT01931.1 - 0.94 8.8 5.9 0.69 9.3 4.5 1.3 1 1 0 1 1 1 0 Domain of Unknown Function (DUF908) Hamartin PF04388.12 KXT01931.1 - 4 6.0 5.2 4.8 5.7 5.2 1.1 1 0 0 1 1 1 0 Hamartin protein NAM-associated PF14303.6 KXT01931.1 - 7.6 7.2 9.6 8.2 7.1 8.6 1.6 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain AtuA PF07287.11 KXT01933.1 - 2.5e-118 394.8 0.1 3.3e-118 394.4 0.1 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA RNA_pol_Rpb1_1 PF04997.12 KXT01934.1 - 2.9e-107 358.6 0.0 4.7e-107 357.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KXT01934.1 - 5.8e-101 337.4 0.1 8.4e-101 336.9 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KXT01934.1 - 5.7e-74 247.9 0.0 1.2e-73 246.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 KXT01934.1 - 6e-59 199.1 2.8 1.2e-58 198.1 2.8 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.12 KXT01934.1 - 8.9e-45 152.0 2.0 1.8e-44 151.0 2.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.18 KXT01934.1 - 3.3e-43 147.3 0.0 6.5e-43 146.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KXT01934.1 - 2.5e-32 111.0 0.1 8.7e-32 109.3 0.1 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 DUF3602 PF12223.8 KXT01934.1 - 0.00028 21.4 2.1 1.1 10.0 0.2 3.7 2 1 1 3 3 3 2 Protein of unknown function (DUF3602) RNA_pol_Rpb1_R PF05001.13 KXT01934.1 - 0.03 14.7 160.4 0.09 13.2 12.4 13.2 7 4 6 14 14 13 0 RNA polymerase Rpb1 C-terminal repeat DZR PF12773.7 KXT01934.1 - 0.17 11.9 0.3 0.41 10.7 0.3 1.5 1 0 0 1 1 1 0 Double zinc ribbon TonB_2 PF13103.6 KXT01934.1 - 0.17 12.1 0.3 0.46 10.8 0.3 1.7 1 0 0 1 1 1 0 TonB C terminal 2OG-FeII_Oxy_3 PF13640.6 KXT01935.1 - 1.9e-09 38.3 0.0 4.4e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GTP_EFTU PF00009.27 KXT01937.1 - 1.7e-49 168.0 0.1 3.7e-49 166.9 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 KXT01937.1 - 8.1e-41 138.5 4.4 1.4e-40 137.7 4.4 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 KXT01937.1 - 5.9e-19 67.9 0.0 1.1e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus Ras PF00071.22 KXT01937.1 - 1.5e-05 24.6 0.0 6.5e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.23 KXT01937.1 - 4.3e-05 23.6 0.1 0.00013 22.0 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase EFG_II PF14492.6 KXT01937.1 - 4.4e-05 23.5 0.0 9.8e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KXT01937.1 - 0.00045 20.6 0.0 0.0011 19.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KXT01937.1 - 0.0022 17.8 0.0 0.0067 16.2 0.0 1.8 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1_Xtn PF16897.5 KXT01937.1 - 0.0076 16.3 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain SRPRB PF09439.10 KXT01937.1 - 0.035 13.5 0.0 0.071 12.5 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Snurportin1 PF11538.8 KXT01937.1 - 0.3 11.3 3.1 0.7 10.1 3.1 1.6 1 0 0 1 1 1 0 Snurportin1 DNA_topoisoIV PF00521.20 KXT01938.1 - 1.3e-125 419.6 0.2 2.9e-125 418.5 0.2 1.6 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 KXT01938.1 - 2.8e-50 169.9 4.7 5.4e-50 169.0 1.0 2.9 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 KXT01938.1 - 4.9e-26 91.3 4.3 1.5e-25 89.7 4.3 1.8 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 KXT01938.1 - 2.5e-12 47.3 0.0 6.2e-12 46.0 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 KXT01938.1 - 1.5e-07 31.6 0.0 6.4e-07 29.5 0.0 2.1 1 0 0 1 1 1 1 Toprim domain Roughex PF06020.11 KXT01939.1 - 0.14 11.2 0.0 0.21 10.6 0.0 1.3 1 1 0 1 1 1 0 Drosophila roughex protein SKG6 PF08693.10 KXT01941.1 - 1.8 8.1 5.1 0.18 11.2 0.5 1.7 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Forkhead PF00250.18 KXT01942.1 - 2.1e-17 63.1 0.1 4.1e-17 62.2 0.1 1.5 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 KXT01942.1 - 0.00065 20.0 0.0 0.0013 19.1 0.0 1.5 1 0 0 1 1 1 1 FHA domain Reticulon PF02453.17 KXT01943.1 - 1.7e-29 102.8 4.3 2.6e-29 102.2 4.3 1.3 1 0 0 1 1 1 1 Reticulon FUSC_2 PF13515.6 KXT01943.1 - 0.91 9.7 8.8 0.15 12.2 1.8 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein-like CoA_transf_3 PF02515.17 KXT01944.1 - 2.7e-38 132.0 0.0 9.2e-36 123.7 0.0 2.3 2 0 0 2 2 2 2 CoA-transferase family III WD40 PF00400.32 KXT01945.1 - 4.2e-45 150.8 23.2 4.7e-09 36.7 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXT01945.1 - 4.8e-09 36.4 0.3 0.065 13.5 0.0 4.3 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXT01945.1 - 2.9e-06 26.2 3.4 0.021 13.5 0.2 4.4 2 1 2 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KXT01945.1 - 0.019 13.9 0.0 10 5.0 0.0 3.7 2 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KXT01945.1 - 0.031 14.2 1.3 20 5.3 0.0 4.3 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KXT01945.1 - 0.033 13.5 0.0 2.2 7.5 0.0 2.6 2 1 0 3 3 3 0 WD40-like domain Aa_trans PF01490.18 KXT01946.1 - 2.5e-24 85.7 29.5 3.1e-24 85.5 29.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein RBP_receptor PF14752.6 KXT01946.1 - 0.011 14.4 0.6 0.011 14.4 0.6 1.6 2 0 0 2 2 2 0 Retinol binding protein receptor zf-C3HC4_2 PF13923.6 KXT01947.1 - 1.1e-10 41.2 11.5 2.1e-10 40.3 11.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXT01947.1 - 1.9e-10 40.9 11.6 3.3e-10 40.1 11.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KXT01947.1 - 5.3e-10 39.2 12.5 1e-09 38.2 12.5 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KXT01947.1 - 8.7e-09 35.1 10.5 1.6e-08 34.3 10.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXT01947.1 - 8.1e-08 32.0 7.6 1.7e-07 31.0 7.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KXT01947.1 - 1.7e-07 31.3 9.7 3.6e-07 30.2 9.7 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING U-box PF04564.15 KXT01947.1 - 4.1e-06 26.9 0.1 1e-05 25.6 0.1 1.7 2 0 0 2 2 1 1 U-box domain Prok-RING_4 PF14447.6 KXT01947.1 - 5.1e-06 26.2 10.4 6.9e-05 22.6 10.7 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KXT01947.1 - 8.6e-06 25.6 9.6 1.7e-05 24.7 9.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KXT01947.1 - 2.2e-05 24.7 11.1 0.00039 20.6 11.1 2.4 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-Nse PF11789.8 KXT01947.1 - 0.00032 20.5 5.6 0.00067 19.4 5.6 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit ZapB PF06005.12 KXT01947.1 - 0.0052 17.2 1.6 0.059 13.8 0.2 1.9 2 1 1 3 3 2 2 Cell division protein ZapB zf-ANAPC11 PF12861.7 KXT01947.1 - 0.02 14.9 5.3 0.2 11.7 2.1 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger HrpB7 PF09486.10 KXT01947.1 - 0.021 15.2 0.4 0.042 14.3 0.4 1.4 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Vac_Fusion PF02346.16 KXT01947.1 - 0.049 13.2 0.3 0.56 9.9 0.1 2.2 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 DUF641 PF04859.12 KXT01947.1 - 0.094 13.1 0.3 0.26 11.6 0.1 1.8 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF1664 PF07889.12 KXT01947.1 - 0.12 12.4 1.2 0.2 11.7 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 KXT01947.1 - 0.13 12.5 0.3 0.13 12.5 0.3 1.6 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) zf-RING_11 PF17123.5 KXT01947.1 - 0.14 11.9 7.6 0.32 10.8 7.6 1.7 1 0 0 1 1 1 0 RING-like zinc finger DUF16 PF01519.16 KXT01947.1 - 0.14 12.6 0.7 0.26 11.8 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 Sec20 PF03908.13 KXT01947.1 - 0.19 11.7 0.7 0.35 10.8 0.7 1.4 1 0 0 1 1 1 0 Sec20 Anti-adapt_IraP PF10796.9 KXT01947.1 - 0.25 11.9 1.3 0.45 11.1 0.2 2.0 3 0 0 3 3 1 0 Sigma-S stabilisation anti-adaptor protein zf-RING_10 PF16685.5 KXT01947.1 - 0.31 11.2 6.0 0.68 10.1 6.0 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 FYVE PF01363.21 KXT01947.1 - 3.7 7.7 11.4 8.1 6.7 11.4 1.6 1 1 0 1 1 1 0 FYVE zinc finger HORMA PF02301.18 KXT01948.1 - 2.8e-30 105.5 0.2 3.8e-30 105.1 0.2 1.2 1 0 0 1 1 1 1 HORMA domain ATG101 PF07855.12 KXT01948.1 - 0.00026 21.0 0.6 0.0009 19.3 0.6 1.8 1 1 0 1 1 1 1 Autophagy-related protein 101 TAF PF02969.17 KXT01948.1 - 0.019 15.2 0.3 0.041 14.0 0.3 1.5 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) DHHA2 PF02833.14 KXT01948.1 - 0.033 14.4 1.1 0.046 13.9 0.8 1.5 1 1 0 1 1 1 0 DHHA2 domain FlxA PF14282.6 KXT01948.1 - 0.05 13.6 2.5 0.05 13.6 2.5 2.4 3 0 0 3 3 3 0 FlxA-like protein Arcadin_1 PF18653.1 KXT01948.1 - 0.051 13.6 2.5 5.1 7.2 0.2 2.3 1 1 1 2 2 2 0 Arcadin 1 DUF3915 PF13054.6 KXT01948.1 - 0.091 12.7 0.2 0.19 11.7 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) UPF0225 PF17775.1 KXT01948.1 - 0.26 12.1 2.6 0.22 12.4 0.7 1.8 2 0 0 2 2 2 0 UPF0225 domain RICH PF05062.12 KXT01948.1 - 1.8 8.9 9.3 0.36 11.2 0.5 2.8 3 0 0 3 3 3 0 RICH domain ADH_N PF08240.12 KXT01961.1 - 2.4e-22 78.9 3.6 3.3e-21 75.2 3.6 2.3 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXT01961.1 - 1e-16 61.1 0.0 1.5e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXT01961.1 - 1.6e-07 31.1 0.0 2.8e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KXT01961.1 - 3.3e-06 26.5 0.1 5.9e-06 25.7 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 KXT01961.1 - 6.8e-05 23.9 0.0 0.00014 22.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TFIIE_beta PF02186.15 KXT01965.1 - 0.11 12.8 0.0 0.17 12.2 0.0 1.2 1 0 0 1 1 1 0 TFIIE beta subunit core domain Zn_clus PF00172.18 KXT01966.1 - 2.7e-09 37.0 25.9 0.00011 22.2 8.5 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3011 PF11218.8 KXT01970.1 - 0.011 15.7 0.1 0.021 14.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3011) DUF1409 PF07197.12 KXT01972.1 - 0.02 14.8 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1409) TDA11 PF17084.5 KXT01976.1 - 0.16 10.9 0.3 0.29 10.0 0.1 1.4 1 1 1 2 2 2 0 Topoisomerase I damage affected protein 11 RNase_H PF00075.24 KXT01978.1 - 5e-16 59.2 0.0 6.4e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 KXT01978.1 - 0.00015 21.6 0.1 0.00039 20.2 0.1 1.7 1 1 0 1 1 1 1 Reverse transcriptase-like CAP_N PF01213.19 KXT01978.1 - 1.8 8.0 5.4 2.4 7.6 5.4 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PI_PP_C PF18365.1 KXT01982.1 - 0.027 14.5 0.1 0.047 13.7 0.1 1.4 1 0 0 1 1 1 0 Phosphoinositide phosphatase C-terminal domain F-box PF00646.33 KXT01983.1 - 0.0037 17.1 0.1 0.0081 16.0 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXT01983.1 - 0.0054 16.6 0.1 0.0099 15.8 0.1 1.5 1 0 0 1 1 1 1 F-box-like RNase_H PF00075.24 KXT01984.1 - 1.1e-15 58.1 0.0 1.4e-15 57.7 0.0 1.1 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 KXT01984.1 - 0.0071 16.2 0.0 0.0098 15.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase-like HTH_11 PF08279.12 KXT01984.1 - 0.21 11.6 0.0 0.46 10.5 0.0 1.6 1 1 0 1 1 1 0 HTH domain DUF3439 PF11921.8 KXT01986.1 - 0.026 14.5 3.1 0.03 14.3 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) IBR PF01485.21 KXT01987.1 - 7.5e-09 35.7 26.1 2e-08 34.3 5.5 3.5 4 0 0 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 KXT01987.1 - 0.0071 16.7 0.3 0.0071 16.7 0.3 3.9 4 1 0 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXT01987.1 - 0.038 13.8 0.2 0.038 13.8 0.2 4.7 4 2 1 5 5 5 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXT01987.1 - 0.15 11.9 0.2 0.15 11.9 0.2 3.7 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf_CopZ PF18423.1 KXT01987.1 - 0.69 9.9 0.0 0.69 9.9 0.0 3.8 4 1 1 5 5 5 0 Zinc binding domain L27_N PF09060.10 KXT01988.1 - 0.18 11.9 1.5 6.4 6.9 0.0 3.4 4 0 0 4 4 4 0 L27_N AMP-binding PF00501.28 KXT01991.1 - 2.6e-16 59.3 0.0 1.7e-15 56.6 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme GH3 PF03321.13 KXT01991.1 - 0.017 14.0 0.0 0.027 13.3 0.0 1.2 1 0 0 1 1 1 0 GH3 auxin-responsive promoter Herpes_DNAp_acc PF04929.12 KXT01993.1 - 0.31 10.0 2.1 0.36 9.7 2.1 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor HET PF06985.11 KXT01995.1 - 1.1e-30 106.8 0.0 2e-30 106.1 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_M14 PF00246.24 KXT01996.1 - 0.028 14.2 0.0 0.03 14.1 0.0 1.1 1 0 0 1 1 1 0 Zinc carboxypeptidase Sulfotransfer_4 PF17784.1 KXT01997.1 - 4.4e-67 226.0 0.0 5.6e-67 225.7 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KXT01997.1 - 0.02 15.3 0.0 0.68 10.3 0.0 2.3 1 1 0 1 1 1 0 Sulfotransferase family MFS_1 PF07690.16 KXT01998.1 - 8.1e-20 71.0 52.1 8.1e-20 71.0 52.1 3.3 2 1 1 3 3 3 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXT01998.1 - 2.3e-10 39.9 16.4 2.3e-10 39.9 16.4 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter CFEM PF05730.11 KXT02001.1 - 0.0004 20.4 7.0 0.00088 19.3 7.0 1.6 1 0 0 1 1 1 1 CFEM domain Glyco_hydro_76 PF03663.14 KXT02002.1 - 1.3e-149 498.7 26.6 1.6e-149 498.4 26.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 2-Hacid_dh_C PF02826.19 KXT02003.1 - 1.8e-45 154.5 0.0 4.4e-45 153.2 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXT02003.1 - 2.1e-05 24.2 0.0 0.0028 17.3 0.0 2.6 2 1 1 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ELFV_dehydrog PF00208.21 KXT02003.1 - 0.0068 16.2 0.0 0.0098 15.6 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_7 PF13241.6 KXT02003.1 - 0.0091 16.4 0.0 0.033 14.6 0.0 1.8 2 0 0 2 2 2 1 Putative NAD(P)-binding AdoHcyase_NAD PF00670.21 KXT02003.1 - 0.014 15.5 0.0 0.051 13.6 0.0 1.8 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.6 KXT02003.1 - 0.13 12.8 0.0 0.8 10.2 0.0 2.0 2 0 0 2 2 2 0 XdhC Rossmann domain F-box PF00646.33 KXT02004.1 - 3.7e-05 23.5 0.0 0.00012 21.9 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXT02004.1 - 0.0001 22.1 2.1 0.00091 19.1 0.1 3.0 2 0 0 2 2 2 1 F-box-like Colipase PF01114.18 KXT02005.1 - 0.056 13.1 2.0 0.36 10.6 0.3 2.6 2 0 0 2 2 2 0 Colipase, N-terminal domain Antig_Caf1 PF09255.10 KXT02005.1 - 0.13 12.4 0.1 0.21 11.7 0.1 1.3 1 0 0 1 1 1 0 Caf1 Capsule antigen SLX9 PF15341.6 KXT02006.1 - 7.8e-33 113.7 6.5 1.3e-32 112.9 6.5 1.4 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 Nucleo_P87 PF07267.11 KXT02006.1 - 1.2 7.9 4.4 1.4 7.7 4.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 F-box-like PF12937.7 KXT02010.1 - 5.7e-05 22.9 0.3 0.00012 21.9 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXT02010.1 - 5.9e-05 22.8 0.2 0.00017 21.4 0.2 1.7 1 0 0 1 1 1 1 F-box domain BTB PF00651.31 KXT02011.1 - 5.9e-10 39.4 0.0 4.5e-08 33.3 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain TPKR_C2 PF16920.5 KXT02011.1 - 0.0076 16.4 0.1 0.022 14.9 0.1 1.8 1 0 0 1 1 1 1 Tyrosine-protein kinase receptor C2 Ig-like domain Pneumo_att_G PF05539.11 KXT02012.1 - 3.2 7.3 14.6 3.6 7.1 14.6 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G BTB PF00651.31 KXT02013.1 - 5.9e-10 39.4 0.0 4.5e-08 33.3 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain TPKR_C2 PF16920.5 KXT02013.1 - 0.0076 16.4 0.1 0.022 14.9 0.1 1.8 1 0 0 1 1 1 1 Tyrosine-protein kinase receptor C2 Ig-like domain RNA_ligase PF09414.10 KXT02017.1 - 8.7e-08 32.6 0.0 1.2e-07 32.2 0.0 1.2 1 0 0 1 1 1 1 RNA ligase Glyco_tranf_2_3 PF13641.6 KXT02019.1 - 7.2e-24 84.9 0.0 1.1e-23 84.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KXT02019.1 - 2.4e-13 50.2 0.0 3.7e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KXT02019.1 - 0.00039 19.9 0.0 0.0013 18.2 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 21 Mg_chelatase PF01078.21 KXT02019.1 - 0.28 10.5 0.1 0.57 9.5 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF5387 PF17361.2 KXT02020.1 - 0.14 11.8 0.2 0.21 11.2 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5387) Pannexin_like PF12534.8 KXT02020.1 - 0.24 10.5 0.3 0.35 9.9 0.3 1.2 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 F-box PF00646.33 KXT02026.1 - 0.00039 20.2 1.6 0.038 13.9 0.2 2.3 2 0 0 2 2 2 2 F-box domain F-box-like PF12937.7 KXT02026.1 - 0.00083 19.2 0.0 0.0039 17.0 0.0 2.1 1 1 0 1 1 1 1 F-box-like HalX PF08663.10 KXT02034.1 - 0.044 14.1 5.6 0.33 11.3 0.2 3.5 4 0 0 4 4 4 0 HalX domain Baculo_PEP_C PF04513.12 KXT02034.1 - 0.65 10.0 1.8 10 6.1 0.1 2.9 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus TerB_C PF15615.6 KXT02034.1 - 2.7 8.3 6.5 0.35 11.2 1.2 2.2 3 0 0 3 3 3 0 TerB-C domain DUF4147 PF13660.6 KXT02035.1 - 0.04 13.5 0.0 0.083 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4147) CSTF2_hinge PF14327.6 KXT02035.1 - 0.086 13.3 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 MctB PF11382.8 KXT02039.1 - 0.031 14.0 0.4 0.038 13.7 0.4 1.1 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB Rotamase PF00639.21 KXT02039.1 - 0.058 14.4 0.1 0.079 13.9 0.1 1.1 1 0 0 1 1 1 0 PPIC-type PPIASE domain DNA_primase_lrg PF04104.14 KXT02039.1 - 0.06 12.7 0.2 0.062 12.7 0.2 1.0 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase, large subunit DUF4250 PF14056.6 KXT02039.1 - 0.93 9.5 4.9 0.48 10.4 1.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4250) DivIC PF04977.15 KXT02039.1 - 1.3 8.8 6.9 8.4 6.3 7.0 2.1 1 1 0 1 1 1 0 Septum formation initiator Ndc1_Nup PF09531.10 KXT02040.1 - 3.6 6.2 8.5 3.9 6.1 8.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3716 PF12511.8 KXT02042.1 - 1.8e-08 34.3 3.2 4e-08 33.2 3.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) FAM163 PF15069.6 KXT02042.1 - 2.4 8.6 4.3 7.2 7.0 4.3 1.7 1 0 0 1 1 1 0 FAM163 family Peroxidase_2 PF01328.17 KXT02043.1 - 1.1e-41 143.4 0.0 1.5e-41 143.0 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 ECH_1 PF00378.20 KXT02044.1 - 1.1e-48 165.8 0.0 3.2e-48 164.2 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXT02044.1 - 5.2e-27 95.2 0.1 3.5e-24 85.9 0.0 2.2 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase GP52 PF17468.2 KXT02047.1 - 0.14 12.3 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 Phage gene product 52 MFS_1 PF07690.16 KXT02048.1 - 3.6e-35 121.5 20.8 1.5e-34 119.5 21.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Peroxidase_2 PF01328.17 KXT02049.1 - 5.4e-51 173.8 0.0 7.8e-51 173.3 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 GMC_oxred_N PF00732.19 KXT02050.1 - 1.4e-60 205.2 0.0 2.2e-60 204.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXT02050.1 - 7.7e-34 117.3 0.0 1.6e-33 116.3 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Thi4 PF01946.17 KXT02050.1 - 0.0014 17.9 0.1 0.0027 17.0 0.1 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KXT02050.1 - 0.0055 16.9 0.2 0.022 15.0 0.2 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXT02050.1 - 0.016 14.3 0.1 0.22 10.5 0.0 2.4 2 1 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 KXT02050.1 - 0.029 13.4 0.1 0.043 12.9 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.24 KXT02050.1 - 0.032 13.8 5.8 0.49 9.9 5.7 2.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase DUF4574 PF15141.6 KXT02055.1 - 6.6 6.7 7.2 4.6 7.2 1.0 3.4 2 1 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 DUF4239 PF14023.6 KXT02055.1 - 6.6 6.4 8.7 3.2 7.4 1.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4239) GST_C PF00043.25 KXT02056.1 - 5.3e-12 45.8 0.0 9e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXT02056.1 - 2.1e-10 40.7 0.0 4.1e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KXT02056.1 - 8.6e-10 38.8 0.0 2.2e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXT02056.1 - 1.1e-09 38.4 0.0 2.4e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXT02056.1 - 6.3e-09 36.1 0.0 1.2e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXT02056.1 - 4.8e-07 29.7 0.0 8.4e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain TolA_bind_tri PF16331.5 KXT02056.1 - 0.11 12.6 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation Aldedh PF00171.22 KXT02057.1 - 6.9e-10 38.0 2.5 9.2e-09 34.3 0.6 2.5 2 1 0 2 2 2 2 Aldehyde dehydrogenase family GFO_IDH_MocA PF01408.22 KXT02058.1 - 6.8e-29 101.1 0.1 8.2e-28 97.6 0.0 2.4 3 0 0 3 3 3 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KXT02058.1 - 0.00099 19.7 0.0 0.0019 18.8 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain AAA_33 PF13671.6 KXT02058.1 - 0.011 15.8 0.7 0.081 13.1 0.1 2.5 2 1 0 2 2 2 0 AAA domain GFO_IDH_MocA_C PF02894.17 KXT02058.1 - 0.054 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain F420_oxidored PF03807.17 KXT02058.1 - 0.063 13.9 0.0 0.25 12.0 0.0 2.1 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent FAM199X PF15814.5 KXT02061.1 - 0.61 9.1 6.8 0.96 8.4 6.8 1.2 1 0 0 1 1 1 0 Protein family FAM199X RAP1 PF07218.11 KXT02061.1 - 5.8 5.1 4.2 8.5 4.5 4.2 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Vac14_Fig4_bd PF11916.8 KXT02063.1 - 0.15 11.8 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Vacuolar protein 14 C-terminal Fig4p binding JmjC PF02373.22 KXT02064.1 - 3e-09 37.3 0.1 8.9e-09 35.8 0.1 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.29 KXT02064.1 - 2.5e-07 30.5 5.7 2.5e-07 30.5 5.7 2.3 2 0 0 2 2 2 1 PHD-finger Cupin_8 PF13621.6 KXT02064.1 - 7.7e-07 29.1 3.7 7.9e-07 29.0 0.0 2.8 4 0 0 4 4 4 1 Cupin-like domain JHD PF17811.1 KXT02064.1 - 2e-06 28.3 0.9 4.8e-06 27.0 0.9 1.6 1 0 0 1 1 1 1 Jumonji helical domain PHD_2 PF13831.6 KXT02064.1 - 0.0073 15.8 2.3 0.0073 15.8 2.3 2.2 2 0 0 2 2 2 1 PHD-finger Dickkopf_N PF04706.12 KXT02064.1 - 3.5 8.2 10.0 6.9 7.2 2.0 2.7 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region Zn_clus PF00172.18 KXT02064.1 - 8.1 6.7 28.4 1.2 9.3 7.0 3.4 3 0 0 3 3 3 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Mcp5_PH PF12814.7 KXT02065.1 - 3.7e-41 140.1 0.0 6.5e-41 139.3 0.0 1.4 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology Fez1 PF06818.15 KXT02065.1 - 0.0009 19.7 12.5 0.0019 18.7 12.5 1.4 1 0 0 1 1 1 1 Fez1 TPR_MLP1_2 PF07926.12 KXT02065.1 - 0.0011 19.0 21.6 0.034 14.2 17.3 2.3 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein DUF3584 PF12128.8 KXT02065.1 - 0.038 11.5 13.9 0.054 11.0 13.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ADIP PF11559.8 KXT02065.1 - 0.79 9.8 18.4 5.6 7.0 3.3 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Exonuc_VII_L PF02601.15 KXT02065.1 - 1.2 8.6 8.1 2.1 7.8 8.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Macoilin PF09726.9 KXT02065.1 - 4.5 5.7 19.0 0.9 8.0 9.0 2.3 2 0 0 2 2 2 0 Macoilin family Golgin_A5 PF09787.9 KXT02065.1 - 6.8 6.1 16.5 12 5.3 16.5 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 Nucleos_tra2_C PF07662.13 KXT02067.1 - 2.1e-69 233.5 2.2 2.1e-69 233.5 2.2 2.5 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 KXT02067.1 - 2.5e-23 82.4 5.0 2.5e-23 82.4 5.0 2.9 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus ATP1G1_PLM_MAT8 PF02038.16 KXT02067.1 - 1.2 8.6 3.7 4.3 6.8 3.7 2.0 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family Gcn1_N PF12074.8 KXT02068.1 - 1.6e-117 392.8 4.0 1.6e-117 392.8 4.0 3.9 4 0 0 4 4 4 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT PF02985.22 KXT02068.1 - 1.1e-30 103.0 40.5 0.077 13.3 0.1 21.8 23 0 0 23 23 21 8 HEAT repeat HEAT_EZ PF13513.6 KXT02068.1 - 2.4e-28 98.2 53.6 8e-07 29.4 0.0 18.8 17 3 6 23 23 21 9 HEAT-like repeat HEAT_2 PF13646.6 KXT02068.1 - 1.1e-19 70.6 54.2 1.1e-05 25.7 0.0 15.0 9 4 10 19 19 18 7 HEAT repeats Cnd1 PF12717.7 KXT02068.1 - 5.7e-14 52.5 7.3 0.27 11.2 1.8 9.5 7 2 3 10 10 9 4 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KXT02068.1 - 2.9e-10 40.6 0.5 1.6 9.3 0.1 8.8 8 2 2 10 10 9 1 Vacuolar 14 Fab1-binding region ParcG PF10274.9 KXT02068.1 - 1e-09 38.8 4.3 0.011 15.9 0.0 6.0 6 1 1 7 7 6 2 Parkin co-regulated protein Adaptin_N PF01602.20 KXT02068.1 - 2.4e-07 29.7 15.1 0.003 16.2 1.7 6.4 6 1 0 6 6 6 3 Adaptin N terminal region TIP120 PF08623.10 KXT02068.1 - 3.7e-05 23.5 0.3 0.47 10.2 0.0 6.3 5 2 1 6 6 6 1 TATA-binding protein interacting (TIP20) Tti2 PF10521.9 KXT02068.1 - 0.00046 19.8 2.2 0.99 8.9 0.0 5.5 5 0 0 5 5 5 1 Tti2 family DUF937 PF06078.11 KXT02068.1 - 0.0014 19.3 4.6 48 4.6 0.1 6.5 4 2 2 6 6 6 0 Bacterial protein of unknown function (DUF937) TAN PF11640.8 KXT02068.1 - 0.018 15.1 0.5 3.8 7.6 0.0 3.6 2 0 0 2 2 2 0 Telomere-length maintenance and DNA damage repair FANCI_S2 PF14676.6 KXT02068.1 - 0.15 12.4 3.0 2.1 8.6 0.1 3.9 4 0 0 4 4 4 0 FANCI solenoid 2 Vitellogenin_N PF01347.22 KXT02068.1 - 0.24 9.7 1.4 0.82 8.0 0.1 2.5 3 0 0 3 3 3 0 Lipoprotein amino terminal region RecC_C PF17946.1 KXT02068.1 - 0.4 10.4 5.0 5.3 6.8 1.6 2.9 2 0 0 2 2 2 0 RecC C-terminal domain Cohesin_HEAT PF12765.7 KXT02068.1 - 1.2 9.6 13.4 1.6e+02 2.7 0.0 7.6 7 0 0 7 7 7 0 HEAT repeat associated with sister chromatid cohesion RTP1_C1 PF10363.9 KXT02068.1 - 2.8 8.2 7.5 43 4.3 0.0 6.2 7 0 0 7 7 6 0 Required for nuclear transport of RNA pol II C-terminus 1 ANAPC4_WD40 PF12894.7 KXT02069.1 - 3.8e-06 27.1 0.2 1.5 9.2 0.0 5.0 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXT02069.1 - 0.0007 20.4 2.9 27 5.8 0.0 5.5 6 1 0 6 6 6 2 WD domain, G-beta repeat PfkB PF00294.24 KXT02070.1 - 5.7e-12 45.6 0.1 9.1e-12 44.9 0.1 1.5 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Glyco_hydro_16 PF00722.21 KXT02072.1 - 1.7e-42 144.9 4.3 3.2e-42 144.0 4.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Laminin_G_2 PF02210.24 KXT02072.1 - 0.0038 17.8 0.1 0.0079 16.8 0.1 1.5 1 0 0 1 1 1 1 Laminin G domain DUF1080 PF06439.11 KXT02072.1 - 0.009 16.1 0.4 0.017 15.2 0.4 1.5 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1080) RRM_1 PF00076.22 KXT02074.1 - 3.7e-18 65.1 0.6 7.3e-18 64.2 0.3 1.6 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXT02074.1 - 2.1e-05 24.1 0.0 2.3e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXT02074.1 - 0.038 13.9 0.0 0.049 13.5 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif TPR_1 PF00515.28 KXT02075.1 - 1.2e-05 24.9 8.6 0.023 14.5 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXT02075.1 - 1.4e-05 24.8 8.7 0.6 10.4 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KXT02075.1 - 9.6e-05 22.5 3.7 0.00015 21.9 2.4 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KXT02075.1 - 0.0024 18.4 2.0 0.012 16.1 1.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXT02075.1 - 0.099 13.5 2.2 0.59 11.1 0.3 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 KXT02075.1 - 0.22 11.6 3.7 0.31 11.1 0.1 3.0 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_16 PF13432.6 KXT02075.1 - 0.54 11.0 4.1 1.5 9.6 0.8 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat F-box-like PF12937.7 KXT02076.1 - 8.9e-05 22.3 0.4 0.00022 21.0 0.4 1.6 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 KXT02076.1 - 0.00024 20.9 0.8 0.0088 16.0 0.0 3.3 3 0 0 3 3 3 1 Leucine Rich repeat LRR_4 PF12799.7 KXT02076.1 - 0.0071 16.7 0.0 29 5.3 0.0 4.5 5 0 0 5 5 5 1 Leucine Rich repeats (2 copies) F-box PF00646.33 KXT02076.1 - 0.096 12.6 0.9 0.28 11.1 0.3 2.1 2 0 0 2 2 2 0 F-box domain Cation_efflux PF01545.21 KXT02077.1 - 3.8e-43 147.5 2.3 3.8e-43 147.5 2.3 3.2 3 2 0 3 3 3 1 Cation efflux family Mito_carr PF00153.27 KXT02079.1 - 7.6e-75 246.9 2.7 1.1e-23 82.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KXT02079.1 - 4.1e-05 22.9 3.7 0.029 13.5 0.0 3.6 2 1 2 4 4 4 3 Gammaproteobacterial serine protease GAD-like PF08887.11 KXT02079.1 - 0.053 13.3 0.0 0.19 11.5 0.0 1.9 1 0 0 1 1 1 0 GAD-like domain Methyltransf_25 PF13649.6 KXT02080.1 - 0.0029 18.3 0.0 0.0067 17.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXT02080.1 - 0.0048 16.7 0.0 0.01 15.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 KXT02080.1 - 0.025 15.6 0.0 0.046 14.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KXT02080.1 - 0.051 14.2 0.0 0.13 13.0 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KXT02080.1 - 0.094 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 KXT02080.1 - 0.18 11.3 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase zf-CCCH_2 PF14608.6 KXT02081.1 - 2.4e-08 34.1 53.3 1.9e-06 28.1 11.4 5.3 5 0 0 5 5 5 4 RNA-binding, Nab2-type zinc finger Nab2 PF11517.8 KXT02081.1 - 0.15 12.4 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Peptidase_C15 PF01470.17 KXT02082.1 - 4e-11 43.5 0.0 1.1e-10 42.0 0.0 1.7 1 1 0 1 1 1 1 Pyroglutamyl peptidase AAA PF00004.29 KXT02083.1 - 8.2e-52 175.1 0.0 1.7e-39 135.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXT02083.1 - 1.1e-12 48.7 1.1 0.0004 20.8 0.3 4.0 4 1 1 5 5 3 2 AAA ATPase domain AAA_lid_3 PF17862.1 KXT02083.1 - 2.6e-11 43.1 0.1 8.4e-11 41.5 0.1 1.9 1 1 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KXT02083.1 - 9.4e-10 38.9 0.2 0.0011 19.2 0.0 3.9 2 2 2 4 4 4 2 AAA domain TIP49 PF06068.13 KXT02083.1 - 1.4e-09 37.7 0.0 0.00025 20.4 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain RuvB_N PF05496.12 KXT02083.1 - 7.5e-08 32.3 1.2 0.024 14.4 0.0 3.9 4 1 1 5 5 4 2 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 KXT02083.1 - 8.6e-08 31.8 0.1 0.0051 16.2 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI CDC48_2 PF02933.17 KXT02083.1 - 9.9e-08 31.7 0.4 3.6e-06 26.7 0.1 2.7 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_5 PF07728.14 KXT02083.1 - 1.9e-07 31.1 0.1 0.002 18.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KXT02083.1 - 2.3e-07 31.1 0.0 9.3e-05 22.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 KXT02083.1 - 2.2e-06 28.2 0.0 0.014 15.9 0.0 3.3 3 0 0 3 3 3 1 AAA domain CDC48_N PF02359.18 KXT02083.1 - 2.5e-06 27.6 0.0 8.3e-06 25.9 0.0 2.0 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_14 PF13173.6 KXT02083.1 - 4.5e-06 26.7 0.0 0.029 14.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KXT02083.1 - 5.7e-06 26.0 0.2 0.045 13.3 0.0 2.7 3 0 0 3 3 2 2 P-loop containing dynein motor region Sigma54_activat PF00158.26 KXT02083.1 - 6e-06 26.1 0.3 0.084 12.6 0.0 3.1 3 0 0 3 3 3 2 Sigma-54 interaction domain ATPase PF06745.13 KXT02083.1 - 7e-06 25.6 0.2 0.01 15.2 0.1 2.6 2 0 0 2 2 2 2 KaiC IstB_IS21 PF01695.17 KXT02083.1 - 7.1e-06 25.9 0.0 0.1 12.3 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_24 PF13479.6 KXT02083.1 - 8.7e-06 25.6 0.0 0.015 15.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KXT02083.1 - 1.2e-05 25.7 0.0 0.041 14.3 0.0 2.6 2 0 0 2 2 2 2 RNA helicase TsaE PF02367.17 KXT02083.1 - 1.2e-05 25.3 0.0 0.11 12.5 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KXT02083.1 - 2e-05 24.8 0.0 0.13 12.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 KXT02083.1 - 2e-05 25.1 1.4 0.043 14.3 0.1 2.8 3 0 0 3 3 2 2 ABC transporter NACHT PF05729.12 KXT02083.1 - 0.00011 22.1 4.2 0.089 12.7 0.1 3.8 3 1 1 4 4 3 1 NACHT domain PhoH PF02562.16 KXT02083.1 - 0.0002 20.9 0.1 0.23 10.9 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein ResIII PF04851.15 KXT02083.1 - 0.00025 21.1 0.1 0.37 10.8 0.0 3.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit NB-ARC PF00931.22 KXT02083.1 - 0.00067 18.9 0.1 1.1 8.4 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain TniB PF05621.11 KXT02083.1 - 0.00069 19.1 0.1 2.9 7.2 0.0 3.7 3 1 0 3 3 3 1 Bacterial TniB protein DEAD PF00270.29 KXT02083.1 - 0.00082 19.2 0.2 0.53 10.0 0.1 3.8 2 2 1 4 4 4 1 DEAD/DEAH box helicase ATPase_2 PF01637.18 KXT02083.1 - 0.00095 19.1 0.4 6.7 6.5 0.0 3.2 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 KXT02083.1 - 0.0013 18.3 0.3 2.5 7.6 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_28 PF13521.6 KXT02083.1 - 0.0017 18.7 0.0 0.23 11.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KXT02083.1 - 0.002 17.2 0.0 0.39 9.7 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_3 PF07726.11 KXT02083.1 - 0.0021 18.0 0.0 0.62 9.9 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KXT02083.1 - 0.0023 17.7 0.5 0.35 10.6 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_11 PF13086.6 KXT02083.1 - 0.003 17.4 0.1 0.5 10.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KXT02083.1 - 0.0061 16.9 0.2 0.72 10.2 0.0 2.9 3 0 0 3 3 3 1 AAA domain Parvo_NS1 PF01057.17 KXT02083.1 - 0.0065 15.6 0.0 0.41 9.7 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 DUF2075 PF09848.9 KXT02083.1 - 0.0097 15.2 0.4 1.1 8.4 0.2 2.6 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) IPT PF01745.16 KXT02083.1 - 0.014 14.8 0.1 0.15 11.4 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase AAA_29 PF13555.6 KXT02083.1 - 0.017 14.8 0.2 1.8 8.4 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_17 PF13207.6 KXT02083.1 - 0.051 14.0 0.1 6.7 7.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KXT02083.1 - 0.059 13.9 1.4 1 9.9 0.0 2.6 2 1 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 KXT02083.1 - 0.07 12.9 0.0 11 5.6 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase Zeta_toxin PF06414.12 KXT02083.1 - 0.09 12.0 0.0 6.4 6.0 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin DUF2076 PF09849.9 KXT02083.1 - 0.098 12.7 6.8 0.2 11.7 6.8 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) SRP54 PF00448.22 KXT02083.1 - 0.11 12.1 0.9 11 5.6 0.0 3.1 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain CPT PF07931.12 KXT02083.1 - 0.11 12.3 0.0 2.8 7.7 0.0 2.6 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Sigma54_activ_2 PF14532.6 KXT02083.1 - 0.13 12.4 0.0 32 4.6 0.0 2.8 3 0 0 3 3 2 0 Sigma-54 interaction domain Rad17 PF03215.15 KXT02083.1 - 0.16 11.9 0.0 3.5 7.5 0.0 2.8 3 0 0 3 3 3 0 Rad17 P-loop domain Sua5_yciO_yrdC PF01300.18 KXT02084.1 - 2.1e-53 180.5 0.0 3e-53 180.0 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 KXT02084.1 - 3.4e-31 108.6 0.0 8.1e-31 107.4 0.0 1.6 1 1 0 1 1 1 1 Putative GTP-binding controlling metal-binding AMP-binding PF00501.28 KXT02085.1 - 3.1e-83 279.7 0.0 3.9e-83 279.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXT02085.1 - 1.1e-14 55.1 0.0 2.4e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MA3 PF02847.17 KXT02086.1 - 1.7e-15 57.0 0.0 3.7e-15 55.9 0.0 1.6 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.19 KXT02086.1 - 3.3e-15 56.3 0.2 5.2e-15 55.7 0.2 1.3 1 0 0 1 1 1 1 MIF4G domain DUF5545 PF17699.1 KXT02086.1 - 0.042 13.7 0.7 0.085 12.7 0.7 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5545) Sugar_tr PF00083.24 KXT02087.1 - 3.8e-98 329.3 19.6 4.4e-98 329.1 19.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXT02087.1 - 4.8e-20 71.8 32.6 3.6e-15 55.7 13.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_L19e PF01280.20 KXT02088.1 - 3e-60 202.5 8.0 1.1e-59 200.7 8.0 2.0 1 0 0 1 1 1 1 Ribosomal protein L19e Helicase_C PF00271.31 KXT02088.1 - 2.9e-16 59.8 0.1 7.6e-16 58.4 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 KXT02088.1 - 4.5e-16 59.1 0.0 4.5e-16 59.1 0.0 2.9 2 0 0 2 2 2 1 Helicase associated domain (HA2) DEAD PF00270.29 KXT02088.1 - 5.5e-10 39.3 0.1 1.2e-09 38.2 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KXT02088.1 - 4.2e-07 30.3 0.4 2.5e-06 27.8 0.1 2.5 2 0 0 2 2 2 1 AAA domain OB_NTP_bind PF07717.16 KXT02088.1 - 0.0001 22.6 0.0 0.00039 20.7 0.0 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold ABC_tran PF00005.27 KXT02088.1 - 0.0081 16.7 0.1 0.059 13.9 0.0 2.5 2 0 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 KXT02088.1 - 0.061 13.2 0.0 0.18 11.7 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase Rad17 PF03215.15 KXT02088.1 - 0.092 12.7 0.0 0.29 11.0 0.0 1.8 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_23 PF13476.6 KXT02088.1 - 0.44 11.0 0.0 0.44 11.0 0.0 3.4 5 0 0 5 5 5 0 AAA domain Band_7 PF01145.25 KXT02089.1 - 5.2e-29 101.5 2.3 8e-29 100.9 2.3 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 KXT02089.1 - 0.044 13.5 0.1 0.077 12.7 0.1 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family RT_RNaseH_2 PF17919.1 KXT02091.1 - 0.0004 20.4 0.0 0.00051 20.0 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KXT02091.1 - 0.038 14.3 0.0 0.046 14.0 0.0 1.2 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase CAS_C PF12026.8 KXT02092.1 - 3.4 7.7 5.7 1.7 8.7 0.1 2.2 2 0 0 2 2 2 0 Crk-Associated Substrate C-terminal domain GMC_oxred_N PF00732.19 KXT02095.1 - 2.6e-40 138.7 0.0 9e-31 107.3 0.0 2.1 2 0 0 2 2 2 2 GMC oxidoreductase FAD_binding_2 PF00890.24 KXT02095.1 - 7.1e-07 28.7 0.1 0.00025 20.3 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KXT02095.1 - 7.3e-06 25.3 0.1 6e-05 22.3 0.1 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 KXT02095.1 - 0.00011 22.0 0.6 0.0012 18.5 0.3 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXT02095.1 - 0.00019 21.6 0.3 0.00045 20.4 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXT02095.1 - 0.00054 19.3 0.0 0.0053 16.0 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXT02095.1 - 0.001 17.9 0.2 0.0045 15.7 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 KXT02095.1 - 0.0014 19.2 0.0 0.24 12.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXT02095.1 - 0.003 16.8 0.0 0.0045 16.3 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KXT02095.1 - 0.025 13.9 0.3 0.09 12.0 0.4 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.25 KXT02096.1 - 4.3e-35 121.0 0.0 6e-35 120.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT02096.1 - 1.6e-31 109.7 0.1 2.4e-31 109.1 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT02096.1 - 5.7e-09 36.1 0.0 9.4e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 KR domain BTB PF00651.31 KXT02097.1 - 1.4e-09 38.2 0.0 2e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Mis14 PF08641.12 KXT02099.1 - 0.046 14.0 3.1 0.073 13.4 3.1 1.3 1 0 0 1 1 1 0 Kinetochore protein Mis14 like Macoilin PF09726.9 KXT02099.1 - 2 6.9 8.2 2.1 6.8 8.2 1.0 1 0 0 1 1 1 0 Macoilin family Pes-10 PF07149.11 KXT02099.1 - 5.2 6.0 7.6 6.5 5.7 7.6 1.1 1 0 0 1 1 1 0 Pes-10 MutS_V PF00488.21 KXT02100.1 - 6e-80 267.7 0.1 1.1e-79 266.8 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KXT02100.1 - 1.4e-36 126.6 0.4 1.4e-36 126.6 0.4 1.9 2 1 0 2 2 2 1 MutS domain III MutS_II PF05188.17 KXT02100.1 - 1.8e-19 70.4 2.2 2.4e-19 70.0 0.0 2.4 3 0 0 3 3 3 1 MutS domain II MutS_IV PF05190.18 KXT02100.1 - 8.6e-18 64.5 0.9 2.6e-17 63.0 0.9 1.9 1 0 0 1 1 1 1 MutS family domain IV MutS_I PF01624.20 KXT02100.1 - 4.7e-15 55.8 0.0 2.7e-13 50.1 0.0 2.6 2 0 0 2 2 2 1 MutS domain I AAA_27 PF13514.6 KXT02100.1 - 0.053 13.1 0.0 0.16 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain KinB_sensor PF16767.5 KXT02100.1 - 0.16 12.4 1.9 1.5 9.3 0.0 2.9 3 0 0 3 3 3 0 Sensor domain of alginate biosynthesis sensor protein KinB 3HCDH_N PF02737.18 KXT02101.1 - 1e-39 136.3 0.0 3e-39 134.8 0.0 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KXT02101.1 - 7.8e-12 45.7 0.0 1.4e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_8 PF13450.6 KXT02101.1 - 0.00027 21.1 0.0 0.00058 20.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 KXT02101.1 - 0.00076 18.8 0.0 0.001 18.4 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 KXT02101.1 - 0.0017 18.0 0.0 0.0022 17.6 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.23 KXT02101.1 - 0.0037 17.3 0.0 0.0053 16.7 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Ldh_1_N PF00056.23 KXT02101.1 - 0.011 15.8 0.0 0.032 14.3 0.0 1.8 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain ApbA PF02558.16 KXT02101.1 - 0.032 13.9 0.0 0.066 12.9 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Thi4 PF01946.17 KXT02101.1 - 0.042 13.1 0.1 0.069 12.4 0.1 1.3 1 0 0 1 1 1 0 Thi4 family 2-Hacid_dh_C PF02826.19 KXT02101.1 - 0.074 12.4 0.0 0.17 11.2 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 KXT02101.1 - 0.088 12.0 0.0 0.2 10.9 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.15 KXT02101.1 - 0.13 12.5 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KXT02101.1 - 0.15 12.6 0.0 0.44 11.2 0.0 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent HTH_43 PF09904.9 KXT02102.1 - 0.036 14.0 0.2 0.71 9.9 0.0 2.8 3 0 0 3 3 3 0 Winged helix-turn helix PC4 PF02229.16 KXT02105.1 - 3.7e-18 64.9 0.1 3.7e-18 64.9 0.1 1.7 2 0 0 2 2 2 1 Transcriptional Coactivator p15 (PC4) SRP14 PF02290.15 KXT02106.1 - 4.5e-31 107.1 0.0 8.5e-31 106.2 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle 14kD protein DUF4460 PF14687.6 KXT02106.1 - 0.067 13.2 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4460) SRP14 PF02290.15 KXT02107.1 - 4.5e-31 107.1 0.0 8.5e-31 106.2 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle 14kD protein DUF4460 PF14687.6 KXT02107.1 - 0.067 13.2 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4460) ELFV_dehydrog PF00208.21 KXT02108.1 - 3.9e-66 223.2 0.0 6e-66 222.6 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 KXT02108.1 - 3.5e-16 58.0 0.1 3e-11 41.7 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 KXT02108.1 - 0.091 12.6 0.0 0.32 10.9 0.0 1.9 2 0 0 2 2 2 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain PDZ_1 PF12812.7 KXT02109.1 - 2e-48 162.3 0.0 9.5e-33 112.1 0.0 2.7 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 KXT02109.1 - 1.6e-27 97.2 0.3 4.2e-21 76.4 0.1 2.7 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ_6 PF17820.1 KXT02109.1 - 3.8e-14 52.3 0.3 4.4e-07 29.7 0.2 4.5 4 0 0 4 4 4 2 PDZ domain PDZ_2 PF13180.6 KXT02109.1 - 2e-13 50.5 0.1 3.9e-05 23.9 0.0 4.5 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.24 KXT02109.1 - 1.2e-10 41.6 0.0 5.1e-05 23.5 0.0 3.5 3 0 0 3 3 3 2 PDZ domain Trypsin PF00089.26 KXT02109.1 - 0.00019 21.3 0.0 0.00048 20.0 0.0 1.6 1 0 0 1 1 1 1 Trypsin 4HPAD_g_N PF18671.1 KXT02109.1 - 0.0013 18.3 0.0 0.014 15.1 0.0 2.6 2 0 0 2 2 2 1 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal Tricorn_PDZ PF14685.6 KXT02109.1 - 0.0044 17.0 0.3 21 5.2 0.1 3.6 3 0 0 3 3 3 0 Tricorn protease PDZ domain Peptidase_S46 PF10459.9 KXT02109.1 - 0.23 10.1 0.1 0.42 9.2 0.1 1.3 1 0 0 1 1 1 0 Peptidase S46 DUF31 PF01732.16 KXT02109.1 - 0.28 10.7 0.2 0.52 9.8 0.2 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF31) Zn_clus PF00172.18 KXT02128.1 - 1.3e-09 38.0 8.3 2.4e-09 37.1 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MIF4G PF02854.19 KXT02130.1 - 4.9e-59 199.5 0.3 1.6e-30 106.4 0.1 3.3 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 KXT02130.1 - 1.5e-42 145.5 2.8 1.5e-42 145.5 2.8 2.7 3 0 0 3 3 3 1 Up-frameshift suppressor 2 Fungal_trans PF04082.18 KXT02131.1 - 5.4e-20 71.5 0.0 9.3e-20 70.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KXT02131.1 - 7.7e-10 38.7 13.4 0.00017 21.9 3.8 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXT02131.1 - 2e-07 31.1 12.9 2.3e-06 27.8 7.1 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXT02131.1 - 5.9e-05 23.6 12.6 0.038 14.8 2.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KXT02131.1 - 4.1 7.3 8.2 14 5.5 0.9 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type ketoacyl-synt PF00109.26 KXT02132.1 - 4.7e-73 245.9 1.5 5.9e-73 245.6 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KXT02132.1 - 1.7e-60 204.0 0.6 4.6e-60 202.6 0.6 1.8 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 KXT02132.1 - 1.6e-50 172.1 0.0 2.6e-50 171.4 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KXT02132.1 - 1.1e-43 150.0 0.1 2e-43 149.1 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXT02132.1 - 1.3e-35 122.0 0.2 1.3e-34 118.7 0.0 2.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 KXT02132.1 - 4.9e-16 58.8 0.2 1.1e-15 57.6 0.2 1.6 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT02132.1 - 9.1e-11 41.8 0.2 1.7e-10 40.8 0.2 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KAsynt_C_assoc PF16197.5 KXT02132.1 - 1.1e-10 42.0 0.0 2.2e-09 37.8 0.0 2.9 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 KXT02132.1 - 1.5e-07 31.6 0.0 5.1e-07 29.9 0.0 1.9 2 0 0 2 2 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 KXT02132.1 - 7.5e-07 28.8 0.1 1.8e-06 27.5 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain ADH_N PF08240.12 KXT02132.1 - 0.0023 17.8 0.0 0.0061 16.4 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KXT02132.1 - 0.02 16.0 0.0 0.16 13.0 0.0 2.6 1 1 1 2 2 2 0 Zinc-binding dehydrogenase ACP_syn_III PF08545.10 KXT02132.1 - 0.02 14.7 1.4 0.22 11.4 1.4 2.8 1 1 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III F420_oxidored PF03807.17 KXT02132.1 - 0.039 14.5 0.4 0.72 10.5 0.2 3.1 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent DSPc PF00782.20 KXT02133.1 - 1.4e-09 37.9 0.0 3e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KXT02133.1 - 1.2e-05 25.0 0.0 2.3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTEN_C2 PF10409.9 KXT02133.1 - 0.0041 16.9 0.0 0.0073 16.1 0.0 1.4 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPn PF14671.6 KXT02133.1 - 0.16 12.4 0.0 0.31 11.5 0.0 1.4 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half Cellulose_synt PF03552.14 KXT02133.1 - 0.17 10.3 0.1 0.56 8.6 0.0 1.7 2 0 0 2 2 2 0 Cellulose synthase SnoaL_2 PF12680.7 KXT02135.1 - 1.9e-05 25.2 0.0 2.4e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 KXT02135.1 - 0.00064 19.5 0.0 0.00076 19.3 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase PdxA PF04166.12 KXT02136.1 - 4.1e-75 252.8 0.0 4.9e-75 252.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal phosphate biosynthetic protein PdxA PdxA PF04166.12 KXT02137.1 - 4.1e-75 252.8 0.0 4.9e-75 252.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal phosphate biosynthetic protein PdxA Putative_PNPOx PF01243.20 KXT02142.1 - 2.2e-11 43.8 0.0 2.4e-10 40.5 0.0 2.4 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 KXT02142.1 - 0.0073 16.3 0.0 0.078 13.0 0.0 2.1 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase FMO-like PF00743.19 KXT02143.1 - 3.6e-19 68.6 0.0 6.6e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KXT02143.1 - 7.3e-07 29.3 0.0 3e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KXT02143.1 - 1.1e-06 28.1 0.0 0.0032 16.7 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KXT02143.1 - 0.00012 21.4 0.0 0.00078 18.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.25 KXT02144.1 - 1.3e-11 44.4 0.0 5.2e-11 42.4 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Csm2_III-A PF03750.13 KXT02144.1 - 0.063 14.1 1.0 0.24 12.3 1.0 2.1 1 1 0 1 1 1 0 Csm2 Type III-A Hormone_3 PF00159.18 KXT02144.1 - 1.2 9.3 3.9 34 4.6 0.0 3.7 3 0 0 3 3 3 0 Pancreatic hormone peptide RPE65 PF03055.15 KXT02146.1 - 3.2e-108 362.9 0.0 3.6e-108 362.7 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein CNOT11 PF10155.9 KXT02147.1 - 0.014 15.5 0.8 4.1 7.6 0.1 2.2 1 1 1 2 2 2 0 CCR4-NOT transcription complex subunit 11 Abhydrolase_3 PF07859.13 KXT02148.1 - 9.9e-37 126.8 0.0 1.3e-36 126.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXT02148.1 - 0.06 12.2 0.2 0.16 10.8 0.2 1.5 1 1 0 1 1 1 0 Carboxylesterase family NmrA PF05368.13 KXT02149.1 - 1.3e-28 100.2 0.2 1.7e-28 99.8 0.2 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXT02149.1 - 1.7e-16 60.7 0.0 2.9e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXT02149.1 - 0.00038 20.0 0.0 0.004 16.6 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Med26 PF08711.11 KXT02149.1 - 0.084 12.9 0.1 0.25 11.4 0.1 1.8 1 0 0 1 1 1 0 TFIIS helical bundle-like domain LIP PF03583.14 KXT02151.1 - 3.6e-11 42.9 0.5 6.7e-05 22.3 0.0 2.1 2 0 0 2 2 2 2 Secretory lipase Abhydrolase_1 PF00561.20 KXT02151.1 - 4.9e-08 32.9 0.2 3.9e-07 30.0 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXT02151.1 - 6.8e-08 33.4 9.8 1.5e-07 32.3 5.8 2.4 2 1 1 3 3 3 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXT02151.1 - 7e-08 32.0 1.2 2.2e-07 30.4 1.2 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KXT02151.1 - 5.3e-05 22.8 0.2 0.003 17.1 0.1 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 KXT02151.1 - 0.0001 21.9 0.1 0.0015 18.1 0.1 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Chlorophyllase PF07224.11 KXT02151.1 - 0.053 12.5 0.1 0.084 11.9 0.1 1.3 1 0 0 1 1 1 0 Chlorophyllase FSH1 PF03959.13 KXT02151.1 - 0.11 12.1 0.0 3.5 7.2 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Palm_thioest PF02089.15 KXT02151.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Carb_anhydrase PF00194.21 KXT02153.1 - 1.6e-29 103.3 0.0 2.5e-29 102.6 0.0 1.3 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase dUTPase PF00692.19 KXT02154.1 - 1.8e-09 37.4 0.0 2.5e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 dUTPase FtsZ_C PF12327.8 KXT02154.1 - 0.082 13.2 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 FtsZ family, C-terminal domain 2OG-FeII_Oxy PF03171.20 KXT02157.1 - 3.2e-20 72.5 0.0 4.9e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cupin_1 PF00190.22 KXT02158.1 - 1.1e-07 31.5 0.0 1.5e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 KXT02158.1 - 2.3e-06 27.2 0.1 3.8e-06 26.5 0.1 1.2 1 0 0 1 1 1 1 Cupin domain ARD PF03079.14 KXT02158.1 - 0.0036 17.5 0.0 0.0052 17.0 0.0 1.3 1 0 0 1 1 1 1 ARD/ARD' family Cupin_6 PF12852.7 KXT02158.1 - 0.03 14.1 0.0 0.033 13.9 0.0 1.1 1 0 0 1 1 1 0 Cupin FSH1 PF03959.13 KXT02159.1 - 7.9e-20 71.4 0.0 1.5e-18 67.2 0.0 2.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) SIR2_2 PF13289.6 KXT02159.1 - 0.17 12.0 0.0 0.47 10.6 0.0 1.8 1 0 0 1 1 1 0 SIR2-like domain Arylsulfotran_2 PF14269.6 KXT02160.1 - 2.5e-54 184.7 3.8 3.9e-54 184.1 3.8 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KXT02160.1 - 4.1e-14 52.3 5.5 1.2e-13 50.8 5.5 1.6 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Amidase PF01425.21 KXT02161.1 - 3.4e-79 266.9 0.2 5.6e-79 266.2 0.2 1.3 1 1 0 1 1 1 1 Amidase Isochorismatase PF00857.20 KXT02161.1 - 2.8e-39 135.1 0.0 6.5e-39 133.9 0.0 1.6 1 0 0 1 1 1 1 Isochorismatase family Nup214_FG PF18617.1 KXT02161.1 - 0.3 11.6 3.1 0.98 10.0 2.5 2.2 2 0 0 2 2 2 0 Nucleoporin Nup214 phenylalanine-glycine (FG) domain Sigma70_r4_2 PF08281.12 KXT02162.1 - 1.7e-14 53.2 0.4 0.0094 15.6 0.0 5.3 5 0 0 5 5 5 4 Sigma-70, region 4 HTH_23 PF13384.6 KXT02162.1 - 5.7e-12 45.1 3.8 0.11 12.3 0.0 5.2 4 1 1 5 5 5 4 Homeodomain-like domain HTH_38 PF13936.6 KXT02162.1 - 2.2e-07 30.5 1.7 0.25 11.2 0.0 4.2 4 0 0 4 4 4 2 Helix-turn-helix domain HTH_24 PF13412.6 KXT02162.1 - 2.9e-07 30.0 0.6 0.03 13.9 0.1 3.8 4 0 0 4 4 4 2 Winged helix-turn-helix DNA-binding GerE PF00196.19 KXT02162.1 - 1.4e-06 27.8 0.3 0.31 10.6 0.0 3.6 3 0 0 3 3 3 2 Bacterial regulatory proteins, luxR family Sigma70_r4 PF04545.16 KXT02162.1 - 1.1e-05 24.8 2.4 0.053 13.0 0.0 4.4 5 0 0 5 5 5 1 Sigma-70, region 4 HTH_7 PF02796.15 KXT02162.1 - 0.00015 21.7 0.2 7.4 6.7 0.0 4.6 4 0 0 4 4 4 1 Helix-turn-helix domain of resolvase MarR_2 PF12802.7 KXT02162.1 - 0.00025 20.9 0.1 0.076 12.9 0.0 3.7 4 0 0 4 4 4 1 MarR family Terminase_5 PF06056.12 KXT02162.1 - 0.00075 19.3 0.1 2.7 8.0 0.0 3.6 3 0 0 3 3 3 1 Putative ATPase subunit of terminase (gpP-like) HTH_29 PF13551.6 KXT02162.1 - 0.00076 19.5 0.1 2.8 8.0 0.0 4.1 3 0 0 3 3 3 1 Winged helix-turn helix HTH_1 PF00126.27 KXT02162.1 - 0.0011 18.9 0.0 0.24 11.4 0.1 2.7 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_28 PF13518.6 KXT02162.1 - 0.002 18.2 3.3 25 5.1 0.1 4.6 4 0 0 4 4 4 0 Helix-turn-helix domain HTH_Tnp_Tc3_1 PF11427.8 KXT02162.1 - 0.0031 17.3 1.3 14 5.6 0.0 4.1 4 0 0 4 4 4 0 Tc3 transposase Myb_DNA-bind_6 PF13921.6 KXT02162.1 - 0.0042 17.3 2.7 13 6.1 0.0 4.2 4 0 0 4 4 4 0 Myb-like DNA-binding domain HTH_11 PF08279.12 KXT02162.1 - 0.0083 16.0 0.2 0.14 12.1 0.0 3.0 3 0 0 3 3 3 1 HTH domain HTH_20 PF12840.7 KXT02162.1 - 0.011 15.8 0.1 2.6 8.2 0.0 3.2 4 0 0 4 4 3 0 Helix-turn-helix domain Sigma70_ECF PF07638.11 KXT02162.1 - 0.028 14.3 0.5 11 5.9 0.0 3.3 3 1 1 4 4 4 0 ECF sigma factor HTH_AsnC-type PF13404.6 KXT02162.1 - 0.028 14.2 0.2 1.7 8.5 0.0 3.3 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain PSD2 PF07624.11 KXT02162.1 - 0.037 13.8 0.1 0.99 9.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1585) MarR PF01047.22 KXT02162.1 - 0.067 13.1 0.0 0.37 10.7 0.0 2.3 2 0 0 2 2 2 0 MarR family DUF2316 PF10078.9 KXT02162.1 - 0.069 13.4 0.0 0.75 10.1 0.0 2.6 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2316) Myb_DNA-binding PF00249.31 KXT02162.1 - 0.083 13.1 1.4 4.2 7.6 0.1 3.4 3 1 0 3 3 2 0 Myb-like DNA-binding domain Fe_dep_repress PF01325.19 KXT02162.1 - 0.089 13.0 0.0 0.3 11.3 0.0 1.9 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain TrmB PF01978.19 KXT02162.1 - 0.13 12.2 1.9 21 5.1 0.0 3.4 4 0 0 4 4 4 0 Sugar-specific transcriptional regulator TrmB DUF3584 PF12128.8 KXT02165.1 - 0.019 12.5 27.9 0.026 12.0 27.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Prominin PF05478.11 KXT02165.1 - 0.04 11.9 15.7 0.055 11.4 15.7 1.1 1 0 0 1 1 1 0 Prominin Ribosomal_S6 PF01250.17 KXT02166.1 - 1.3e-24 86.3 0.0 1.6e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 Pkinase PF00069.25 KXT02167.1 - 6.4e-12 45.4 0.0 7e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT02167.1 - 0.0011 18.3 0.0 0.0014 18.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXT02168.1 - 6.4e-12 45.4 0.0 7e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT02168.1 - 0.0011 18.3 0.0 0.0014 18.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RhoGAP PF00620.27 KXT02169.1 - 7.3e-43 146.0 0.0 3.8e-42 143.7 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 KXT02169.1 - 6.2e-12 45.6 0.9 6.2e-12 45.6 0.9 2.1 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain HTH_57 PF18679.1 KXT02169.1 - 0.72 10.2 2.6 1.3 9.4 0.1 2.7 3 1 1 4 4 4 0 ThcOx helix turn helix domain Rpp20 PF12328.8 KXT02170.1 - 1.2e-31 109.5 11.8 3e-31 108.2 11.8 1.6 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 KXT02170.1 - 6e-13 48.4 2.2 1.2e-12 47.5 0.4 2.3 3 0 0 3 3 3 1 Alba ApoLp-III PF07464.11 KXT02170.1 - 0.015 15.4 1.6 0.099 12.7 0.1 2.2 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF4666 PF15697.5 KXT02170.1 - 2 9.1 6.0 1.3 9.7 1.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4666) Vfa1 PF08432.10 KXT02170.1 - 5 7.4 7.7 18 5.6 7.7 1.8 1 1 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 AAA PF00004.29 KXT02171.1 - 6.5e-15 55.7 0.0 2e-14 54.1 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXT02171.1 - 0.00073 19.5 0.0 0.0018 18.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KXT02171.1 - 0.00083 19.8 0.5 0.0056 17.1 0.5 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXT02171.1 - 0.0029 17.9 3.6 0.017 15.4 0.1 3.2 1 1 2 3 3 3 1 AAA domain AAA_33 PF13671.6 KXT02171.1 - 0.053 13.7 0.1 0.24 11.6 0.1 2.2 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KXT02171.1 - 0.076 12.4 0.0 0.18 11.1 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 KXT02171.1 - 0.076 12.8 0.0 0.076 12.8 0.0 4.2 2 1 0 2 2 2 0 AAA domain MFS_1 PF07690.16 KXT02172.1 - 2.6e-27 95.7 42.3 3e-27 95.5 40.2 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXT02172.1 - 9.7e-05 21.0 24.1 0.00036 19.1 24.2 1.8 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KXT02174.1 - 2.6e-27 95.7 42.3 3e-27 95.5 40.2 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXT02174.1 - 9.7e-05 21.0 24.1 0.00036 19.1 24.2 1.8 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Gemini_V2 PF01524.17 KXT02175.1 - 0.073 13.3 0.0 0.099 12.9 0.0 1.2 1 0 0 1 1 1 0 Geminivirus V2 protein FixS PF03597.15 KXT02175.1 - 0.19 11.5 0.0 0.33 10.7 0.0 1.3 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type SRP9-21 PF05486.12 KXT02176.1 - 3.2e-32 110.8 0.2 3.2e-32 110.8 0.2 1.5 2 0 0 2 2 2 1 Signal recognition particle 9 kDa protein (SRP9) Pmp3 PF01679.17 KXT02177.1 - 6.9e-20 71.0 10.6 9.5e-20 70.6 10.6 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF872 PF05915.12 KXT02177.1 - 0.83 9.8 3.2 5.8 7.1 2.0 2.1 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF872) zf-C2H2 PF00096.26 KXT02178.1 - 1.1e-08 35.1 27.3 0.019 15.4 0.8 7.3 7 1 0 7 7 7 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXT02178.1 - 9.4e-07 29.2 26.7 0.087 13.7 0.6 7.1 6 1 0 6 6 6 4 C2H2-type zinc finger zf-met PF12874.7 KXT02178.1 - 0.015 15.7 11.4 0.6 10.6 0.0 4.8 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf_C2H2_ZHX PF18387.1 KXT02178.1 - 0.017 14.7 1.4 0.89 9.2 0.3 2.7 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_8 PF15909.5 KXT02178.1 - 0.069 13.5 12.2 0.25 11.7 1.3 3.6 3 0 0 3 3 3 0 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 KXT02178.1 - 2.2 8.4 12.8 0.054 13.5 1.5 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger FSH1 PF03959.13 KXT02179.1 - 4.9e-35 121.1 0.0 8.1e-35 120.4 0.0 1.3 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 KXT02179.1 - 7.2e-05 22.7 0.0 0.0064 16.3 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase DUF389 PF04087.14 KXT02179.1 - 0.0081 16.2 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF389) BAAT_C PF08840.11 KXT02179.1 - 0.016 15.1 0.1 0.038 13.9 0.1 1.5 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.20 KXT02179.1 - 0.041 13.5 0.3 0.43 10.2 0.0 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXT02179.1 - 0.06 12.6 0.1 0.2 10.9 0.1 1.8 1 1 1 2 2 2 0 Serine aminopeptidase, S33 DUF3089 PF11288.8 KXT02179.1 - 0.085 12.4 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Glyco_transf_8 PF01501.20 KXT02180.1 - 0.00056 19.5 0.1 0.001 18.7 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 8 Cutinase PF01083.22 KXT02181.1 - 9e-43 146.3 0.1 1.1e-42 146.0 0.1 1.1 1 0 0 1 1 1 1 Cutinase Thioesterase PF00975.20 KXT02181.1 - 0.00069 19.8 0.0 0.00083 19.5 0.0 1.1 1 0 0 1 1 1 1 Thioesterase domain PE-PPE PF08237.11 KXT02181.1 - 0.017 14.7 0.1 0.024 14.2 0.1 1.2 1 0 0 1 1 1 0 PE-PPE domain Lipase_3 PF01764.25 KXT02181.1 - 0.037 13.9 0.0 0.055 13.3 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) Fungal_trans PF04082.18 KXT02182.1 - 9.4e-26 90.4 0.8 1.4e-25 89.8 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT02182.1 - 0.0009 19.3 9.8 0.001 19.2 8.8 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CDC4_D PF16856.5 KXT02182.1 - 0.074 12.9 0.6 0.26 11.2 0.1 2.1 2 0 0 2 2 2 0 Cell division control protein 4 dimerisation domain Dicty_REP PF05086.12 KXT02182.1 - 0.13 10.2 3.1 8.6 4.2 5.7 2.0 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein RhgB_N PF09284.10 KXT02183.1 - 1.4e-104 349.0 2.1 2.2e-104 348.4 2.1 1.3 1 0 0 1 1 1 1 Rhamnogalacturonan lyase B, N-terminal CBM-like PF14683.6 KXT02183.1 - 6.7e-34 117.1 0.0 2.2e-33 115.5 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 KXT02183.1 - 2.3e-24 85.0 5.3 7.7e-24 83.3 5.3 2.0 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 KXT02183.1 - 0.0003 21.0 1.5 0.0003 21.0 1.5 3.2 4 0 0 4 4 4 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 KXT02183.1 - 0.027 14.4 0.4 0.32 11.0 0.1 2.7 1 1 1 2 2 2 0 CarboxypepD_reg-like domain fn3_5 PF06280.12 KXT02183.1 - 0.061 14.0 0.9 0.27 11.9 0.0 2.4 3 0 0 3 3 3 0 Fn3-like domain DUF2012 PF09430.10 KXT02183.1 - 0.083 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2012) BRCT_2 PF16589.5 KXT02183.1 - 0.09 13.2 0.0 3.8 8.0 0.0 3.0 3 0 0 3 3 3 0 BRCT domain, a BRCA1 C-terminus domain Clr2_transil PF16761.5 KXT02183.1 - 0.14 13.0 0.0 0.32 11.9 0.0 1.5 1 0 0 1 1 1 0 Transcription-silencing protein, cryptic loci regulator Clr2 Rep_fac-A_3 PF08661.11 KXT02184.1 - 2.3e-11 44.0 0.1 1.4e-09 38.3 0.0 2.1 2 0 0 2 2 2 2 Replication factor A protein 3 AA_permease_2 PF13520.6 KXT02185.1 - 3.5e-51 174.4 54.9 4.7e-51 174.0 54.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXT02185.1 - 1.2e-18 67.1 38.7 1.8e-18 66.4 38.7 1.2 1 0 0 1 1 1 1 Amino acid permease DUF4692 PF15763.5 KXT02186.1 - 0.025 15.1 4.4 0.031 14.7 4.4 1.2 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) DUF4638 PF15472.6 KXT02186.1 - 0.15 11.8 1.2 0.19 11.5 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) TUSC2 PF15000.6 KXT02186.1 - 1.3 9.4 3.8 1.9 8.8 0.0 2.2 2 0 0 2 2 2 0 Tumour suppressor candidate 2 Zn_clus PF00172.18 KXT02187.1 - 8.4e-06 25.8 5.3 8.4e-06 25.8 5.3 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Totivirus_coat PF05518.11 KXT02187.1 - 0.13 10.3 0.4 0.15 10.0 0.4 1.2 1 0 0 1 1 1 0 Totivirus coat protein IMUP PF15761.5 KXT02187.1 - 4.1 8.1 10.1 6.3 7.5 4.4 2.3 2 0 0 2 2 2 0 Immortalisation up-regulated protein V-SNARE_C PF12352.8 KXT02188.1 - 1e-13 51.3 0.2 1e-13 51.3 0.2 1.9 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KXT02188.1 - 5.5e-07 29.4 0.0 2.2e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 Sec20 KxDL PF10241.9 KXT02188.1 - 0.01 16.1 1.0 5 7.5 0.1 2.7 2 1 1 3 3 3 0 Uncharacterized conserved protein Metal_resist PF13801.6 KXT02188.1 - 0.053 13.7 0.2 0.053 13.7 0.2 2.1 3 0 0 3 3 3 0 Heavy-metal resistance Snapin_Pallidin PF14712.6 KXT02188.1 - 0.061 13.7 0.8 0.33 11.4 0.1 2.1 2 0 0 2 2 2 0 Snapin/Pallidin DIOX_N PF14226.6 KXT02189.1 - 1e-25 90.8 0.0 1.4e-25 90.3 0.0 1.1 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Transp_cyt_pur PF02133.15 KXT02191.1 - 4.7e-98 328.8 33.6 5.8e-98 328.5 33.6 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin BTB PF00651.31 KXT02192.1 - 0.029 14.6 0.0 0.07 13.4 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain DUF2742 PF10888.8 KXT02192.1 - 0.096 13.0 0.0 2.4 8.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2742) BTB PF00651.31 KXT02193.1 - 0.029 14.6 0.0 0.07 13.4 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain DUF2742 PF10888.8 KXT02193.1 - 0.096 13.0 0.0 2.4 8.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2742) GCV_H PF01597.19 KXT02194.1 - 1.4e-37 128.3 1.7 2.8e-35 120.9 0.3 2.1 1 1 1 2 2 2 2 Glycine cleavage H-protein GCV_H PF01597.19 KXT02195.1 - 1.4e-37 128.3 1.7 2.8e-35 120.9 0.3 2.1 1 1 1 2 2 2 2 Glycine cleavage H-protein BTB PF00651.31 KXT02196.1 - 0.029 14.6 0.0 0.07 13.4 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain DUF2742 PF10888.8 KXT02196.1 - 0.096 13.0 0.0 2.4 8.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2742) BTB PF00651.31 KXT02197.1 - 0.029 14.6 0.0 0.07 13.4 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain DUF2742 PF10888.8 KXT02197.1 - 0.096 13.0 0.0 2.4 8.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2742) DUF1308 PF07000.11 KXT02198.1 - 4.4e-14 52.8 0.0 2.3e-13 50.4 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1308) SKA2 PF16740.5 KXT02198.1 - 0.073 12.9 0.1 2.5 7.9 0.1 2.8 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 MFS_1 PF07690.16 KXT02199.1 - 6.4e-36 124.0 25.9 6.4e-36 124.0 25.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily GATase_4 PF13230.6 KXT02200.1 - 9.6e-13 47.6 0.0 8.2e-10 38.0 0.0 3.1 3 0 0 3 3 3 3 Glutamine amidotransferases class-II GATase_6 PF13522.6 KXT02200.1 - 9e-08 32.4 0.0 1.7e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain YrvL PF14184.6 KXT02200.1 - 0.21 11.7 0.0 0.34 11.0 0.0 1.3 1 0 0 1 1 1 0 Regulatory protein YrvL DUF3042 PF11240.8 KXT02209.1 - 0.0019 18.2 0.2 0.0055 16.7 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3042) HSBP1 PF06825.12 KXT02209.1 - 0.098 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Heat shock factor binding protein 1 Pkinase PF00069.25 KXT02210.1 - 4.4e-72 242.6 0.0 6.8e-72 242.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT02210.1 - 6.3e-35 120.7 0.0 1.1e-34 119.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXT02210.1 - 0.002 17.5 0.0 0.0034 16.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXT02210.1 - 0.0032 16.3 0.0 0.0032 16.3 0.0 4.0 4 1 0 4 4 4 1 Fungal protein kinase Kdo PF06293.14 KXT02210.1 - 0.0052 16.2 0.0 0.0052 16.2 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KXT02210.1 - 0.0084 15.1 0.1 0.026 13.5 0.1 1.7 2 0 0 2 2 2 1 Haspin like kinase domain MUG113 PF13455.6 KXT02211.1 - 6.2e-23 81.3 0.1 1.5e-22 80.1 0.1 1.6 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.9 KXT02211.1 - 1.9e-22 79.8 0.4 9.3e-22 77.5 0.0 2.3 2 0 0 2 2 2 1 T5orf172 domain DUF1768 PF08719.11 KXT02214.1 - 4.7e-54 183.0 0.1 5.9e-54 182.7 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Flavin_Reduct PF01613.18 KXT02215.1 - 1.7e-14 54.2 0.0 2.3e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain DnaJ PF00226.31 KXT02216.1 - 1e-21 76.8 0.8 2e-21 75.9 0.8 1.5 1 0 0 1 1 1 1 DnaJ domain P66_CC PF16563.5 KXT02216.1 - 0.0096 15.5 2.6 0.036 13.7 2.6 2.0 1 0 0 1 1 1 1 Coiled-coil and interaction region of P66A and P66B with MBD2 Ax_dynein_light PF10211.9 KXT02216.1 - 1.1 9.1 9.3 2.6 7.9 0.2 2.5 1 1 1 2 2 2 0 Axonemal dynein light chain DUF4140 PF13600.6 KXT02216.1 - 1.4 9.4 10.5 2 8.9 2.3 2.8 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) SHE3 PF17078.5 KXT02216.1 - 1.4 8.6 11.3 8.7 6.0 0.2 3.0 3 0 0 3 3 3 0 SWI5-dependent HO expression protein 3 DUF3391 PF11871.8 KXT02216.1 - 1.7 9.2 7.8 0.31 11.6 1.2 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3391) OmpH PF03938.14 KXT02216.1 - 2.6 8.4 9.4 49 4.3 6.5 3.0 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) DivIC PF04977.15 KXT02216.1 - 5.2 6.9 8.8 4.1 7.2 1.4 2.4 2 0 0 2 2 2 0 Septum formation initiator Sugar_tr PF00083.24 KXT02220.1 - 1.7e-68 231.6 29.1 2e-68 231.4 29.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXT02220.1 - 9.2e-16 57.7 40.1 7.2e-12 44.9 24.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Tail_VII PF17091.5 KXT02220.1 - 0.21 11.5 7.4 0.72 9.8 0.1 3.2 3 0 0 3 3 3 0 Inovirus G7P protein Bac_rhamnosid6H PF17389.2 KXT02221.1 - 1.4e-12 47.5 0.4 5.2e-12 45.7 0.4 1.8 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Glyco_hydro_2_N PF02837.18 KXT02221.1 - 0.0016 18.3 0.0 0.0034 17.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_36 PF17167.4 KXT02221.1 - 0.046 12.4 0.0 0.077 11.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain Bac_rhamnosid_N PF08531.10 KXT02221.1 - 0.065 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Alpha-L-rhamnosidase N-terminal domain Glyco_hydro_92 PF07971.12 KXT02222.1 - 5.8e-140 467.3 0.5 7.3e-140 466.9 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KXT02222.1 - 9.1e-60 202.5 0.4 1.5e-59 201.8 0.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain NmrA PF05368.13 KXT02222.1 - 1.5e-09 37.8 0.0 8.5e-07 28.8 0.0 2.7 2 1 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 KXT02222.1 - 1.2e-07 31.8 0.0 2.9e-07 30.5 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXT02222.1 - 0.00011 21.8 0.0 0.00034 20.2 0.0 1.7 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Amidohydro_3 PF07969.11 KXT02223.1 - 3e-32 112.7 0.3 4.9e-32 112.0 0.3 1.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KXT02223.1 - 3.9e-08 33.0 0.4 0.0018 17.6 0.0 3.2 3 0 0 3 3 3 2 Amidohydrolase family PPR_long PF17177.4 KXT02223.1 - 0.087 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP DS PF01916.17 KXT02224.1 - 3.5e-134 446.6 0.0 4e-134 446.4 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Carbam_trans_N PF02543.15 KXT02224.1 - 0.094 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus Myosin_head PF00063.21 KXT02225.1 - 4.4e-261 867.9 0.0 6.7e-261 867.3 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 KXT02225.1 - 6e-27 94.0 2.6 3.3e-26 91.6 2.6 2.4 1 0 0 1 1 1 1 DIL domain IQ PF00612.27 KXT02225.1 - 1.4e-09 36.9 31.1 0.00012 21.6 0.1 6.3 7 0 0 7 7 6 4 IQ calmodulin-binding motif Myosin_N PF02736.19 KXT02225.1 - 0.00011 21.9 2.1 0.0003 20.6 2.1 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 KXT02225.1 - 0.0033 17.7 0.0 0.015 15.5 0.0 2.2 1 0 0 1 1 1 1 AAA domain KASH_CCD PF14662.6 KXT02225.1 - 0.052 13.4 26.7 0.13 12.1 11.0 2.9 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH AAA_16 PF13191.6 KXT02225.1 - 0.08 13.3 0.8 0.31 11.4 0.0 2.4 2 0 0 2 2 1 0 AAA ATPase domain Sec34 PF04136.15 KXT02225.1 - 0.081 12.8 3.5 0.28 11.0 3.5 2.0 1 0 0 1 1 1 0 Sec34-like family ATPase PF06745.13 KXT02225.1 - 0.15 11.4 2.4 15 4.8 0.0 2.9 2 0 0 2 2 2 0 KaiC ABC_tran PF00005.27 KXT02225.1 - 0.16 12.5 2.3 3.2 8.3 0.0 3.1 2 1 0 2 2 2 0 ABC transporter Leu_zip PF15294.6 KXT02225.1 - 0.16 11.5 17.0 1.1 8.8 17.0 2.4 1 1 0 1 1 1 0 Leucine zipper GAS PF13851.6 KXT02225.1 - 0.33 10.3 28.0 1.9 7.8 10.6 2.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 KXT02225.1 - 0.33 11.1 33.2 3.4 7.9 10.7 2.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) AAA_13 PF13166.6 KXT02225.1 - 1.5 7.4 17.9 8.3 4.9 17.9 2.0 1 1 0 1 1 1 0 AAA domain CENP-F_leu_zip PF10473.9 KXT02225.1 - 2.9 7.9 23.2 0.5 10.4 5.9 2.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TolA_bind_tri PF16331.5 KXT02225.1 - 3.3 7.9 29.9 0.15 12.2 4.8 4.8 3 1 1 4 4 4 0 TolA binding protein trimerisation Atg14 PF10186.9 KXT02225.1 - 3.3 6.7 24.5 4.2 6.4 7.9 2.4 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 BRE1 PF08647.11 KXT02225.1 - 3.6 7.7 24.1 10 6.2 8.8 3.2 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase FUSC PF04632.12 KXT02225.1 - 4.9 5.6 16.3 0.046 12.3 7.2 1.9 2 0 0 2 2 2 0 Fusaric acid resistance protein family YabA PF06156.13 KXT02225.1 - 8.7 7.0 15.7 13 6.5 4.6 3.1 1 1 1 2 2 2 0 Initiation control protein YabA Mito_carr PF00153.27 KXT02227.1 - 1.6e-10 40.7 2.2 0.0056 16.6 0.1 4.4 3 2 0 3 3 3 3 Mitochondrial carrier protein CDC45 PF02724.14 KXT02227.1 - 0.012 14.0 0.0 0.016 13.5 0.0 1.1 1 0 0 1 1 1 0 CDC45-like protein MotA_ExbB PF01618.16 KXT02227.1 - 0.15 11.8 0.1 0.79 9.5 0.0 2.0 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family NAP PF00956.18 KXT02228.1 - 1.6e-26 93.1 1.2 2.7e-26 92.4 1.2 1.3 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) PerC PF06069.11 KXT02228.1 - 0.035 14.4 0.0 0.11 12.8 0.0 1.8 1 0 0 1 1 1 0 PerC transcriptional activator DUF5625 PF18539.1 KXT02228.1 - 0.075 13.3 0.0 2.3 8.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5625) Ferritin_2 PF13668.6 KXT02229.1 - 7.8e-41 139.5 4.5 1.1e-40 139.0 4.5 1.2 1 0 0 1 1 1 1 Ferritin-like domain DUF4439 PF14530.6 KXT02229.1 - 0.012 16.3 0.3 0.027 15.2 0.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4439) DUF455 PF04305.14 KXT02229.1 - 0.017 14.7 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF455) BTB PF00651.31 KXT02230.1 - 5.1e-08 33.1 0.0 1.3e-07 31.8 0.0 1.8 1 1 0 1 1 1 1 BTB/POZ domain AAA_25 PF13481.6 KXT02231.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain Mito_carr PF00153.27 KXT02232.1 - 1.3e-65 217.4 2.0 7e-21 74.0 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.32 KXT02233.1 - 1.3e-39 133.5 17.7 4.5e-09 36.8 0.1 12.0 13 0 0 13 13 13 7 WD domain, G-beta repeat Utp12 PF04003.12 KXT02233.1 - 1.7e-23 83.0 0.2 2.5e-23 82.4 0.2 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KXT02233.1 - 1.6e-16 60.4 0.0 0.47 10.8 0.0 9.3 5 2 4 10 10 10 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXT02233.1 - 5.3e-05 23.2 1.0 0.063 13.1 0.0 5.0 4 1 3 7 7 7 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KXT02233.1 - 0.00013 21.1 2.1 1.3 8.0 0.1 5.6 5 2 2 7 7 7 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KXT02233.1 - 0.00038 19.2 3.0 0.34 9.5 0.0 4.2 3 2 1 4 4 4 2 Nucleoporin Nup120/160 WD40_like PF17005.5 KXT02233.1 - 0.02 14.2 0.0 6.7 5.9 0.0 3.3 3 0 0 3 3 3 0 WD40-like domain PQQ_3 PF13570.6 KXT02233.1 - 0.86 10.2 10.5 1.7 9.2 0.0 5.2 5 0 0 5 5 5 0 PQQ-like domain Beta-lactamase PF00144.24 KXT02234.1 - 2.1e-45 155.4 2.4 4.6e-45 154.3 2.4 1.5 1 1 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 KXT02234.1 - 1.2e-05 25.7 0.1 0.00019 21.8 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3471) MFS_1 PF07690.16 KXT02235.1 - 6.6e-36 124.0 22.8 6.6e-36 124.0 22.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KXT02235.1 - 2.5e-05 23.8 3.5 2.9e-05 23.5 0.1 2.2 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Flp_Fap PF04964.14 KXT02236.1 - 0.12 12.2 2.2 0.24 11.3 2.2 1.4 1 0 0 1 1 1 0 Flp/Fap pilin component Phage_holin_3_6 PF07332.11 KXT02236.1 - 1 9.4 4.9 0.18 11.8 0.3 2.0 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III BTB PF00651.31 KXT02239.1 - 5.1e-09 36.3 0.0 8.2e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BLOC1_2 PF10046.9 KXT02242.1 - 4.1e-05 23.8 1.0 0.3 11.4 0.7 2.5 1 1 1 2 2 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 Snapin_Pallidin PF14712.6 KXT02242.1 - 0.0003 21.2 0.8 0.00062 20.1 0.7 1.6 1 1 0 1 1 1 1 Snapin/Pallidin SKA2 PF16740.5 KXT02242.1 - 0.014 15.2 0.4 0.033 14.0 0.4 1.6 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 Fib_alpha PF08702.10 KXT02242.1 - 0.028 14.6 0.6 0.11 12.6 0.4 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ABC_tran_CTD PF16326.5 KXT02242.1 - 0.065 13.5 5.3 0.057 13.7 2.7 2.1 1 1 1 2 2 2 0 ABC transporter C-terminal domain DUF4795 PF16043.5 KXT02242.1 - 0.081 12.5 1.1 0.11 12.1 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Exonuc_VII_L PF02601.15 KXT02242.1 - 0.13 11.8 2.5 0.17 11.5 2.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Glyco_hydro_79C PF16862.5 KXT02243.1 - 4e-20 72.6 0.1 1.1e-19 71.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain Pkinase PF00069.25 KXT02244.1 - 5.9e-61 206.1 0.0 7.1e-36 123.9 0.0 3.6 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KXT02244.1 - 1.7e-36 125.9 0.0 3.4e-18 65.9 0.0 3.5 3 0 0 3 3 3 3 Protein tyrosine kinase HGTP_anticodon2 PF12745.7 KXT02244.1 - 5.2e-32 111.4 0.4 5.2e-32 111.4 0.4 2.0 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs tRNA-synt_His PF13393.6 KXT02244.1 - 3.6e-11 42.9 6.1 1.5e-10 40.8 0.0 2.5 2 0 0 2 2 2 1 Histidyl-tRNA synthetase RWD PF05773.22 KXT02244.1 - 8.7e-08 32.5 0.0 2.2e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 RWD domain Kinase-like PF14531.6 KXT02244.1 - 0.011 15.1 0.0 0.81 8.9 0.0 2.4 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 KXT02244.1 - 0.011 15.6 4.3 0.021 14.7 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF1682 PF07946.14 KXT02244.1 - 1.5 7.9 8.4 1.1 8.4 6.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) Pkinase PF00069.25 KXT02245.1 - 4.3e-62 209.9 0.0 5.5e-37 127.6 0.0 3.6 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KXT02245.1 - 8.1e-37 126.9 0.0 1.6e-18 66.9 0.0 3.5 3 0 0 3 3 3 3 Protein tyrosine kinase HGTP_anticodon2 PF12745.7 KXT02245.1 - 5e-32 111.5 0.4 5e-32 111.5 0.4 2.0 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs tRNA-synt_His PF13393.6 KXT02245.1 - 3.3e-11 43.0 6.1 1.5e-10 40.9 0.0 2.5 2 0 0 2 2 2 1 Histidyl-tRNA synthetase RWD PF05773.22 KXT02245.1 - 8.6e-08 32.5 0.0 2.1e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 RWD domain APH PF01636.23 KXT02245.1 - 0.01 15.8 4.3 0.021 14.8 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KXT02245.1 - 0.011 15.1 0.0 0.81 8.9 0.0 2.4 2 0 0 2 2 2 0 Kinase-like DUF1682 PF07946.14 KXT02245.1 - 1.4 8.0 8.4 1 8.5 6.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) DIT1_PvcA PF05141.12 KXT02246.1 - 2.2e-95 319.3 0.0 3.3e-95 318.7 0.0 1.3 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein ABC2_membrane PF01061.24 KXT02246.1 - 5.4e-78 261.2 45.9 4.8e-41 140.5 18.1 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 KXT02246.1 - 1.8e-30 106.3 0.0 6.9e-14 52.5 0.0 3.3 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 KXT02246.1 - 2.6e-28 97.8 9.4 3.3e-26 91.0 0.0 3.4 4 0 0 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.6 KXT02246.1 - 1.7e-12 47.7 0.0 5.3e-12 46.2 0.0 1.9 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KXT02246.1 - 2.2e-08 34.7 0.3 0.00013 22.4 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KXT02246.1 - 8e-06 25.8 0.2 0.00079 19.4 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 KXT02246.1 - 3.2e-05 23.6 1.3 0.058 13.1 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 KXT02246.1 - 8e-05 22.2 0.0 0.0094 15.4 0.0 3.1 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KXT02246.1 - 0.00022 21.1 0.1 0.96 9.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KXT02246.1 - 0.00022 20.8 0.2 0.0016 18.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KXT02246.1 - 0.00084 19.9 0.0 0.043 14.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KXT02246.1 - 0.0045 16.7 0.0 0.77 9.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KXT02246.1 - 0.0048 17.1 0.0 0.76 9.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KXT02246.1 - 0.0053 17.0 0.7 0.97 9.7 0.2 3.1 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 KXT02246.1 - 0.015 15.2 0.6 1.8 8.5 0.1 2.7 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 KXT02246.1 - 0.051 13.8 0.1 1.5 9.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KXT02246.1 - 0.088 12.9 0.0 15 5.7 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase dNK PF01712.19 KXT02246.1 - 0.1 12.4 0.0 4.6 7.0 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_5 PF07728.14 KXT02246.1 - 0.11 12.5 0.5 14 5.7 0.1 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) T2SSE PF00437.20 KXT02246.1 - 0.14 11.2 0.4 7.6 5.5 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_23 PF13476.6 KXT02246.1 - 0.22 12.0 0.2 1.4 9.3 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KXT02246.1 - 0.27 10.9 0.1 4.3 6.9 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain WW_1 PF18507.1 KXT02246.1 - 0.27 10.9 1.5 0.87 9.3 0.0 2.6 3 0 0 3 3 2 0 WW domain cobW PF02492.19 KXT02246.1 - 2.3 7.8 5.0 2.6 7.6 0.8 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC2_membrane_3 PF12698.7 KXT02246.1 - 4.8 6.2 38.9 0.024 13.8 11.1 3.4 2 2 1 3 3 3 0 ABC-2 family transporter protein Torus PF16131.5 KXT02247.1 - 4.1e-41 140.1 0.1 1.1e-40 138.7 0.1 1.8 2 0 0 2 2 2 1 Torus domain RRM_1 PF00076.22 KXT02247.1 - 2.9e-06 27.0 0.0 6.1e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 KXT02247.1 - 0.00036 20.5 0.6 0.00036 20.5 0.6 1.9 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH PF00642.24 KXT02247.1 - 0.044 13.7 0.8 0.085 12.8 0.8 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nup35_RRM_2 PF14605.6 KXT02247.1 - 0.061 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif AMP-binding PF00501.28 KXT02248.1 - 7e-27 94.1 0.0 1.1e-26 93.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 KXT02248.1 - 6.8e-09 36.0 1.5 5.3e-08 33.1 0.1 2.6 2 0 0 2 2 2 1 Phosphopantetheine attachment site Transferase PF02458.15 KXT02248.1 - 3.2e-05 22.8 0.0 0.15 10.7 0.0 2.8 3 0 0 3 3 3 2 Transferase family Se-cys_synth_N PF12390.8 KXT02248.1 - 0.085 13.1 0.2 0.36 11.1 0.0 2.2 2 0 0 2 2 2 0 Selenocysteine synthase N terminal AMP-binding PF00501.28 KXT02249.1 - 6.7e-23 81.0 0.0 1e-22 80.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 KXT02249.1 - 6.9e-09 35.9 1.5 5.4e-08 33.1 0.1 2.6 2 0 0 2 2 2 1 Phosphopantetheine attachment site Transferase PF02458.15 KXT02249.1 - 3.3e-05 22.8 0.0 0.15 10.6 0.0 2.8 3 0 0 3 3 3 2 Transferase family Se-cys_synth_N PF12390.8 KXT02249.1 - 0.086 13.1 0.2 0.36 11.1 0.0 2.2 2 0 0 2 2 2 0 Selenocysteine synthase N terminal Myb_DNA-binding PF00249.31 KXT02250.1 - 3.2e-15 56.1 0.2 2.6e-07 30.7 0.0 2.9 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KXT02250.1 - 5.5e-06 26.2 0.0 8.1e-05 22.5 0.0 2.7 2 0 0 2 2 2 1 Myb DNA-binding like Glyco_hydro_88 PF07470.13 KXT02251.1 - 6.4e-13 48.5 0.2 1.5e-12 47.3 0.1 1.5 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 Fungal_trans_2 PF11951.8 KXT02252.1 - 1.3e-20 73.6 2.4 9.5e-12 44.4 0.3 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT02252.1 - 3.9e-06 26.9 9.9 8.8e-06 25.8 9.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease_2 PF13520.6 KXT02253.1 - 1.2e-41 143.0 52.1 1.6e-41 142.5 52.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXT02253.1 - 1.1e-21 77.0 47.1 1.7e-21 76.4 47.1 1.2 1 0 0 1 1 1 1 Amino acid permease DUF267 PF03268.14 KXT02253.1 - 0.24 10.2 10.0 2.4 6.9 0.5 2.5 2 0 0 2 2 2 0 Caenorhabditis protein of unknown function, DUF267 NDUF_B12 PF08122.12 KXT02254.1 - 3.2e-24 84.7 0.6 4.6e-24 84.2 0.6 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Abhydrolase_3 PF07859.13 KXT02255.1 - 2e-43 148.7 0.0 2.7e-43 148.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 KXT02255.1 - 0.059 12.9 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 Dienelactone hydrolase family Say1_Mug180 PF10340.9 KXT02255.1 - 0.096 11.5 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 KXT02256.1 - 2.5e-41 141.9 0.0 1.8e-40 139.1 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 KXT02256.1 - 0.039 13.5 0.0 0.093 12.3 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family Say1_Mug180 PF10340.9 KXT02256.1 - 0.11 11.4 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KXT02256.1 - 0.11 11.9 0.0 14 5.0 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Glyco_hydro_61 PF03443.14 KXT02257.1 - 2.2e-05 24.5 0.1 3.4e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 HTH_Crp_2 PF13545.6 KXT02258.1 - 0.077 13.0 0.2 0.38 10.8 0.1 2.2 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain GTP_cyclohydroI PF01227.22 KXT02259.1 - 2.9e-73 245.1 0.1 3.7e-73 244.8 0.1 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 KXT02259.1 - 0.0034 17.5 0.0 0.0065 16.6 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein STE3 PF02076.15 KXT02261.1 - 2.6e-80 269.8 21.6 3.2e-80 269.4 21.6 1.1 1 0 0 1 1 1 1 Pheromone A receptor PfkB PF00294.24 KXT02262.1 - 1.4e-57 195.4 1.7 1.5e-57 195.2 1.7 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Fer4_24 PF18109.1 KXT02263.1 - 0.025 14.8 0.4 0.059 13.7 0.4 1.6 1 0 0 1 1 1 0 Ferredoxin I 4Fe-4S cluster domain Tropomyosin_1 PF12718.7 KXT02263.1 - 0.081 13.1 7.2 0.11 12.6 3.5 2.1 1 1 1 2 2 2 0 Tropomyosin like FYRC PF05965.14 KXT02263.1 - 0.13 12.5 0.7 4.2 7.6 0.1 2.4 1 1 1 2 2 2 0 F/Y rich C-terminus PSI PF01437.25 KXT02264.1 - 1.1e-05 25.8 9.7 1.9e-05 25.1 9.7 1.5 1 0 0 1 1 1 1 Plexin repeat PSI_integrin PF17205.3 KXT02264.1 - 0.019 14.7 12.5 0.03 14.1 12.5 1.5 1 1 0 1 1 1 0 Integrin plexin domain 2OG-FeII_Oxy_3 PF13640.6 KXT02265.1 - 4.3e-10 40.4 0.1 9.4e-10 39.3 0.1 1.5 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.25 KXT02266.1 - 2.2e-67 227.2 0.0 2.8e-67 226.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT02266.1 - 9.2e-30 103.8 0.0 1.4e-29 103.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXT02266.1 - 0.0017 17.8 0.0 0.0047 16.3 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KXT02266.1 - 0.0069 15.4 0.0 0.0099 14.9 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KXT02266.1 - 0.019 13.7 0.0 0.028 13.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Septin PF00735.18 KXT02267.1 - 8.3e-114 379.6 0.1 1.2e-113 379.0 0.1 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KXT02267.1 - 3.9e-07 30.1 0.0 8e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXT02267.1 - 7.6e-06 25.9 0.0 8.1e-05 22.6 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KXT02267.1 - 1.5e-05 24.6 2.0 0.00023 20.8 0.3 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KXT02267.1 - 0.00063 20.0 0.4 0.0023 18.2 0.0 2.2 2 1 0 2 2 2 1 AAA domain Pox_A32 PF04665.12 KXT02267.1 - 0.0035 16.8 0.0 0.006 16.1 0.0 1.3 1 0 0 1 1 1 1 Poxvirus A32 protein FOXP-CC PF16159.5 KXT02267.1 - 0.009 16.6 1.8 0.03 14.9 1.8 2.0 1 0 0 1 1 1 1 FOXP coiled-coil domain Roc PF08477.13 KXT02267.1 - 0.0092 16.2 0.1 0.019 15.1 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase IIGP PF05049.13 KXT02267.1 - 0.012 14.7 0.0 0.022 13.8 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AIG1 PF04548.16 KXT02267.1 - 0.013 14.9 0.0 0.025 13.9 0.0 1.5 1 0 0 1 1 1 0 AIG1 family Casc1_N PF15927.5 KXT02267.1 - 0.018 14.8 8.9 0.044 13.5 8.9 1.6 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus AAA_24 PF13479.6 KXT02267.1 - 0.019 14.7 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXT02267.1 - 0.023 15.1 0.6 0.069 13.5 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain KAP_NTPase PF07693.14 KXT02267.1 - 0.048 12.9 0.0 0.065 12.5 0.0 1.5 1 1 0 1 1 1 0 KAP family P-loop domain T2SSE PF00437.20 KXT02267.1 - 0.067 12.2 0.3 0.13 11.3 0.0 1.5 2 0 0 2 2 2 0 Type II/IV secretion system protein Ras PF00071.22 KXT02267.1 - 0.071 12.7 0.1 0.18 11.4 0.1 1.7 1 0 0 1 1 1 0 Ras family NACHT PF05729.12 KXT02267.1 - 0.085 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 KXT02267.1 - 0.094 13.2 0.3 0.32 11.5 0.0 1.9 2 0 0 2 2 2 0 ABC transporter PduV-EutP PF10662.9 KXT02267.1 - 0.14 11.9 0.3 5.2 6.8 0.3 2.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 KXT02267.1 - 0.37 10.8 5.9 4.8 7.2 0.1 3.1 2 1 1 3 3 3 0 Dynamin family DUF1664 PF07889.12 KXT02267.1 - 0.7 9.9 4.4 0.9 9.6 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Myc-LZ PF02344.15 KXT02267.1 - 1.8 8.7 7.2 6.5 6.9 0.9 2.7 2 0 0 2 2 2 0 Myc leucine zipper domain AAA_11 PF13086.6 KXT02267.1 - 7.3 6.3 6.6 44 3.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain adh_short PF00106.25 KXT02268.1 - 1.1e-26 93.5 0.0 1.4e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT02268.1 - 1.7e-18 67.0 0.0 2.3e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT02268.1 - 9.3e-08 32.2 0.0 2e-07 31.1 0.0 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXT02268.1 - 8.1e-06 25.5 0.0 1.3e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KXT02268.1 - 0.00097 18.3 0.0 0.0019 17.4 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KXT02268.1 - 0.001 19.0 0.0 0.0014 18.6 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXT02268.1 - 0.0069 16.0 0.1 0.011 15.3 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 KXT02268.1 - 0.0084 15.3 0.0 0.012 14.8 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.24 KXT02268.1 - 0.089 13.2 0.0 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 KXT02269.1 - 3.2e-69 233.1 0.0 3.9e-69 232.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXT02269.1 - 2.5e-09 37.3 0.0 3.5e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding DUF3431 PF11913.8 KXT02270.1 - 1.5e-86 289.7 0.0 2.3e-86 289.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) UCH PF00443.29 KXT02271.1 - 2.2e-11 43.8 0.0 3.3e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-C3HC4_3 PF13920.6 KXT02271.1 - 3.3e-11 42.9 8.1 5.2e-11 42.2 8.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) MORN PF02493.20 KXT02271.1 - 4.8e-08 32.4 15.0 0.0001 22.0 0.0 4.7 4 0 0 4 4 4 3 MORN repeat Prok-RING_4 PF14447.6 KXT02271.1 - 3e-05 23.8 8.4 5.5e-05 22.9 8.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 MATH PF00917.26 KXT02271.1 - 0.0024 18.0 0.0 1.4 9.1 0.0 2.5 2 0 0 2 2 2 2 MATH domain zf-RING_2 PF13639.6 KXT02271.1 - 0.0078 16.5 8.8 0.016 15.5 8.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KXT02271.1 - 0.16 12.1 4.3 0.84 9.7 4.3 2.2 1 1 1 2 2 2 0 RING-type zinc-finger DUF2039 PF10217.9 KXT02271.1 - 0.17 12.2 5.4 0.37 11.2 5.4 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) zf-RING_5 PF14634.6 KXT02271.1 - 1.2 9.2 9.0 2.3 8.3 9.0 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KXT02271.1 - 1.3 8.9 9.7 3.1 7.7 9.7 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) AMP-binding PF00501.28 KXT02272.1 - 4.5e-59 200.1 0.0 6.7e-59 199.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.20 KXT02272.1 - 1.2e-23 84.4 0.0 4.3e-23 82.6 0.0 2.0 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.7 KXT02272.1 - 2.7e-07 31.4 1.9 6.7e-07 30.1 1.9 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family PP-binding PF00550.25 KXT02272.1 - 1.1e-05 25.7 0.0 2.3e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_1 PF00561.20 KXT02272.1 - 0.032 13.9 0.0 0.069 12.8 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.18 KXT02272.1 - 0.038 13.5 0.0 0.072 12.6 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family Pkinase PF00069.25 KXT02273.1 - 1.2e-21 77.3 0.0 1.6e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT02273.1 - 1e-18 67.6 0.0 1.3e-18 67.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXT02273.1 - 0.00034 20.6 0.2 0.00045 20.2 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KXT02273.1 - 0.00049 19.5 0.1 0.00085 18.7 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KXT02273.1 - 0.003 17.2 0.0 0.0047 16.5 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 KXT02273.1 - 0.011 15.1 0.0 0.03 13.6 0.0 1.8 2 0 0 2 2 2 0 Kinase-like LPD24 PF18839.1 KXT02273.1 - 0.017 15.3 0.0 0.042 14.1 0.0 1.6 2 0 0 2 2 2 0 Large polyvalent protein associated domain 24 Seadorna_VP7 PF07387.11 KXT02273.1 - 0.086 11.9 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 CAF1 PF04857.20 KXT02274.1 - 2.4e-20 72.9 0.0 2e-10 40.4 0.0 2.2 2 0 0 2 2 2 2 CAF1 family ribonuclease Terminase_GpA PF05876.12 KXT02285.1 - 0.037 12.6 0.0 0.069 11.7 0.0 1.4 1 1 1 2 2 2 0 Phage terminase large subunit (GpA) UCH PF00443.29 KXT02286.1 - 1.2e-38 133.0 0.0 1.8e-38 132.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KXT02286.1 - 2e-25 88.9 12.5 4.6e-21 74.9 1.9 3.1 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 KXT02286.1 - 1e-24 86.1 1.5 7.5e-23 80.1 0.1 2.9 2 0 0 2 2 2 1 Variant UBP zinc finger UBA PF00627.31 KXT02286.1 - 4.5e-19 68.0 0.0 1.6e-08 34.3 0.0 2.7 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.6 KXT02286.1 - 7.5e-16 58.6 0.0 7.4e-14 52.1 0.0 3.2 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.6 KXT02286.1 - 0.023 14.5 0.0 0.048 13.5 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain Helicase_C PF00271.31 KXT02287.1 - 1.3e-19 70.6 0.0 7.9e-16 58.4 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 KXT02287.1 - 8.6e-19 68.0 0.0 1.5e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 KXT02287.1 - 0.00021 22.0 0.4 0.00048 20.8 0.4 1.6 1 0 0 1 1 1 1 RecQ zinc-binding SNF2_N PF00176.23 KXT02287.1 - 0.026 13.2 0.0 0.035 12.8 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain MarR_2 PF12802.7 KXT02287.1 - 0.081 12.8 0.0 0.31 10.9 0.0 2.1 1 0 0 1 1 1 0 MarR family HSF_DNA-bind PF00447.17 KXT02288.1 - 2.8e-31 108.0 0.9 5.3e-31 107.1 0.9 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.24 KXT02288.1 - 3.2e-22 78.8 0.0 6.9e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Gp58 PF07902.11 KXT02288.1 - 2.3 6.4 4.0 3.4 5.9 4.0 1.1 1 0 0 1 1 1 0 gp58-like protein Ribosomal_S17 PF00366.20 KXT02289.1 - 4.4e-15 55.5 5.4 9.3e-15 54.5 5.4 1.6 1 0 0 1 1 1 1 Ribosomal protein S17 DUF948 PF06103.11 KXT02291.1 - 1.6 9.0 9.2 4 7.8 0.3 3.9 5 0 0 5 5 5 0 Bacterial protein of unknown function (DUF948) DUF948 PF06103.11 KXT02292.1 - 1.9 8.8 9.5 4.1 7.7 0.3 4.1 5 0 0 5 5 5 0 Bacterial protein of unknown function (DUF948) zf-C2H2 PF00096.26 KXT02293.1 - 5.6e-08 32.8 34.1 0.0065 16.9 5.7 6.4 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXT02293.1 - 0.00051 20.7 29.3 0.051 14.4 4.3 6.4 6 0 0 6 6 6 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXT02293.1 - 0.025 15.0 0.4 0.025 15.0 0.4 4.8 5 0 0 5 5 5 0 Zinc-finger double domain zf-HIT PF04438.16 KXT02293.1 - 0.13 12.2 2.0 1.1 9.2 0.1 2.8 2 0 0 2 2 2 0 HIT zinc finger zf-BED PF02892.15 KXT02293.1 - 0.23 11.5 6.8 0.11 12.6 1.1 2.5 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_11 PF16622.5 KXT02293.1 - 0.45 10.3 7.9 0.38 10.6 3.8 2.9 2 0 0 2 2 2 0 zinc-finger C2H2-type ET PF01684.16 KXT02293.1 - 0.64 10.4 5.1 2.5 8.5 0.2 2.6 2 0 0 2 2 2 0 ET module zf-met PF12874.7 KXT02293.1 - 0.76 10.3 10.4 43 4.7 0.1 4.7 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KXT02293.1 - 0.92 9.9 17.1 5.5 7.4 0.1 5.2 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KXT02294.1 - 5.6e-08 32.8 34.1 0.0065 16.9 5.7 6.4 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXT02294.1 - 0.00051 20.7 29.3 0.051 14.4 4.3 6.4 6 0 0 6 6 6 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXT02294.1 - 0.025 15.0 0.4 0.025 15.0 0.4 4.8 5 0 0 5 5 5 0 Zinc-finger double domain zf-HIT PF04438.16 KXT02294.1 - 0.13 12.2 2.0 1.1 9.2 0.1 2.8 2 0 0 2 2 2 0 HIT zinc finger zf-BED PF02892.15 KXT02294.1 - 0.23 11.5 6.8 0.11 12.6 1.1 2.5 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_11 PF16622.5 KXT02294.1 - 0.45 10.3 7.9 0.38 10.6 3.8 2.9 2 0 0 2 2 2 0 zinc-finger C2H2-type ET PF01684.16 KXT02294.1 - 0.64 10.4 5.1 2.5 8.5 0.2 2.6 2 0 0 2 2 2 0 ET module zf-met PF12874.7 KXT02294.1 - 0.76 10.3 10.4 43 4.7 0.1 4.7 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KXT02294.1 - 0.92 9.9 17.1 5.5 7.4 0.1 5.2 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding RCR PF12273.8 KXT02295.1 - 8.6e-24 84.5 9.0 1.1e-23 84.1 9.0 1.1 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red 7tm_3 PF00003.22 KXT02295.1 - 0.031 14.0 0.2 0.038 13.7 0.2 1.1 1 0 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR Rhabdo_glycop PF00974.18 KXT02295.1 - 0.23 9.9 0.1 0.32 9.4 0.1 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein NrsF PF06532.11 KXT02296.1 - 0.071 12.8 9.3 0.17 11.6 9.3 1.6 1 1 0 1 1 1 0 Negative regulator of sigma F ABC2_membrane_4 PF12730.7 KXT02296.1 - 0.53 10.2 10.5 82 3.1 10.5 2.0 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF2628 PF10947.8 KXT02296.1 - 6.7 7.1 8.2 1 9.7 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) Peptidase_M43 PF05572.13 KXT02297.1 - 3e-11 43.5 0.4 5.3e-11 42.7 0.4 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 KXT02297.1 - 0.0048 17.4 1.0 0.022 15.3 1.0 2.2 1 1 1 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KXT02297.1 - 0.008 16.0 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Matrixin Reprolysin_5 PF13688.6 KXT02297.1 - 0.071 13.2 0.9 0.14 12.3 0.9 1.6 1 1 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M66 PF10462.9 KXT02297.1 - 0.19 10.7 3.1 0.25 10.3 1.5 1.7 1 1 0 2 2 2 0 Peptidase M66 ADH_zinc_N PF00107.26 KXT02299.1 - 2.6e-24 85.6 1.0 6.6e-24 84.3 0.7 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXT02299.1 - 3e-14 52.8 1.1 3.3e-13 49.5 1.1 2.3 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KXT02299.1 - 3.9e-09 37.7 0.0 8.7e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KXT02299.1 - 0.00028 20.2 1.4 0.00041 19.7 1.4 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KXT02299.1 - 0.04 13.3 0.1 0.073 12.4 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Zn_clus PF00172.18 KXT02300.1 - 1.8e-05 24.7 9.7 2.9e-05 24.1 9.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Elf1 PF05129.13 KXT02300.1 - 0.012 15.6 2.4 0.019 15.0 2.4 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Fungal_trans PF04082.18 KXT02301.1 - 2.7e-14 52.9 0.8 4.7e-14 52.1 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT02301.1 - 0.00016 21.7 9.7 0.00029 20.9 9.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Elf1 PF05129.13 KXT02301.1 - 0.19 11.8 3.2 0.44 10.6 3.2 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Zn_clus PF00172.18 KXT02302.1 - 1.8e-05 24.7 9.7 2.9e-05 24.1 9.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Elf1 PF05129.13 KXT02302.1 - 0.012 15.6 2.4 0.019 15.0 2.4 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like RTA1 PF04479.13 KXT02304.1 - 5.1e-68 228.8 8.8 5.1e-68 228.8 8.8 1.7 1 1 1 2 2 2 1 RTA1 like protein DUF3483 PF11982.8 KXT02304.1 - 0.0024 17.5 0.3 0.0056 16.3 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3483) DUF4293 PF14126.6 KXT02304.1 - 0.68 10.2 8.8 0.64 10.3 0.2 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4293) Sugar_tr PF00083.24 KXT02305.1 - 1.4e-105 353.8 23.1 1.6e-105 353.6 23.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXT02305.1 - 6.7e-25 87.7 30.8 4.4e-23 81.8 17.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KXT02305.1 - 0.0016 16.8 2.8 0.0016 16.8 2.8 2.9 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family Phage_holin_3_2 PF04550.12 KXT02305.1 - 0.41 11.2 7.7 0.33 11.5 2.9 2.6 2 0 0 2 2 2 0 Phage holin family 2 Fungal_trans_2 PF11951.8 KXT02306.1 - 1.5e-11 43.8 0.1 3.1e-10 39.4 0.0 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Kisspeptin PF15152.6 KXT02306.1 - 0.081 13.7 0.0 0.32 11.8 0.0 2.1 1 0 0 1 1 1 0 Kisspeptin Herpes_pp85 PF04637.12 KXT02306.1 - 0.21 10.0 0.4 0.29 9.5 0.4 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF2530 PF10745.9 KXT02307.1 - 0.18 12.1 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) DUF2530 PF10745.9 KXT02308.1 - 0.18 12.1 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) MFS_1 PF07690.16 KXT02309.1 - 4.2e-23 81.9 54.9 1.1e-18 67.4 34.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily AFG1_ATPase PF03969.16 KXT02310.1 - 3.4e-13 49.2 0.0 6.5e-12 45.0 0.0 2.0 2 0 0 2 2 2 2 AFG1-like ATPase Sugar_tr PF00083.24 KXT02314.1 - 2.2e-82 277.4 30.9 2.5e-82 277.2 30.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXT02314.1 - 1.3e-26 93.4 28.4 6.3e-26 91.1 25.9 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXT02314.1 - 0.00082 17.9 4.3 0.00082 17.9 4.3 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Ost4 PF10215.9 KXT02314.1 - 0.34 10.8 3.2 0.24 11.2 0.2 2.5 2 0 0 2 2 2 0 Oligosaccaryltransferase Arf PF00025.21 KXT02315.1 - 7.4e-40 136.2 0.1 1.5e-39 135.2 0.1 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KXT02315.1 - 2.2e-16 59.9 0.0 2.7e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXT02315.1 - 2.9e-14 53.3 0.0 4.3e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KXT02315.1 - 3.9e-07 29.7 0.0 9e-07 28.5 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KXT02315.1 - 6.4e-05 23.0 0.0 0.00012 22.1 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KXT02315.1 - 0.00061 19.2 0.0 0.0008 18.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KXT02315.1 - 0.0054 16.3 0.0 0.015 14.9 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KXT02315.1 - 0.0063 16.1 0.5 0.18 11.4 0.1 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 KXT02315.1 - 0.027 14.5 0.0 0.047 13.7 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain G-alpha PF00503.20 KXT02315.1 - 0.045 12.9 0.3 0.2 10.8 0.1 1.9 1 1 1 2 2 2 0 G-protein alpha subunit Dynamin_N PF00350.23 KXT02315.1 - 0.078 13.0 0.0 0.41 10.7 0.1 1.9 1 1 1 2 2 2 0 Dynamin family PduV-EutP PF10662.9 KXT02315.1 - 0.14 11.9 0.1 2.2 8.0 0.0 2.4 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation adh_short PF00106.25 KXT02316.1 - 2.2e-28 99.1 0.0 3.3e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT02316.1 - 1.9e-24 86.5 0.0 3.6e-24 85.6 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT02316.1 - 5.9e-05 23.1 0.1 0.015 15.2 0.1 2.2 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 KXT02316.1 - 0.041 13.3 0.1 0.14 11.6 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KXT02316.1 - 0.11 11.8 0.2 0.23 10.8 0.0 1.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Pro_racemase PF05544.11 KXT02317.1 - 2.8e-115 384.8 0.0 3.6e-115 384.5 0.0 1.1 1 0 0 1 1 1 1 Proline racemase ATP_transf PF09830.9 KXT02317.1 - 1.1e-12 47.9 0.0 2.5e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 ATP adenylyltransferase TauD PF02668.16 KXT02320.1 - 3.9e-34 118.7 0.2 5.1e-34 118.3 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family AAA_5 PF07728.14 KXT02320.1 - 0.065 13.2 0.0 0.57 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RRM_1 PF00076.22 KXT02321.1 - 3.6e-12 45.9 0.0 5e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KXT02321.1 - 0.0052 16.8 0.0 0.0074 16.3 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DEAD_2 PF06733.15 KXT02322.1 - 1.6e-51 174.4 0.0 2.9e-51 173.6 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 KXT02322.1 - 2e-47 161.4 0.8 4.6e-42 143.9 0.2 2.4 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 KXT02322.1 - 2.3e-44 151.6 0.5 5.2e-44 150.4 0.0 1.9 2 0 0 2 2 2 1 Helicase C-terminal domain Methyltransf_31 PF13847.6 KXT02322.1 - 0.12 12.2 0.1 4.6 7.0 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain NFACT-C PF11923.8 KXT02323.1 - 3.4e-40 136.2 0.1 3.4e-40 136.2 0.1 3.6 3 0 0 3 3 3 1 NFACT protein C-terminal domain adh_short PF00106.25 KXT02323.1 - 8.7e-37 126.5 0.1 1.4e-34 119.3 0.0 2.8 2 1 0 2 2 2 1 short chain dehydrogenase NFACT-R_1 PF05670.13 KXT02323.1 - 5e-30 104.4 0.0 1.2e-29 103.1 0.0 1.7 1 0 0 1 1 1 1 NFACT protein RNA binding domain adh_short_C2 PF13561.6 KXT02323.1 - 1.5e-29 103.3 0.7 1.3e-27 96.9 0.0 3.4 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase FbpA PF05833.11 KXT02323.1 - 6.5e-29 101.0 15.6 6.5e-29 101.0 15.6 2.2 2 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) KR PF08659.10 KXT02323.1 - 0.00015 21.7 3.2 0.00035 20.5 0.1 2.5 2 0 0 2 2 2 1 KR domain ADH_zinc_N PF00107.26 KXT02323.1 - 0.023 14.7 0.0 0.073 13.1 0.0 1.9 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Phage_Gp19 PF09355.10 KXT02323.1 - 0.33 11.4 4.2 1.4 9.4 0.0 3.3 2 0 0 2 2 2 0 Phage protein Gp19/Gp15/Gp42 FMO-like PF00743.19 KXT02324.1 - 1.4e-19 69.9 0.0 1.2e-17 63.6 0.0 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KXT02324.1 - 7.3e-10 38.9 0.0 2e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXT02324.1 - 3.3e-09 36.4 0.0 8.4e-07 28.5 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXT02324.1 - 9.1e-08 31.6 0.1 1.4e-05 24.5 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KXT02324.1 - 5.4e-07 29.1 0.0 0.0031 16.8 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXT02324.1 - 0.0016 18.1 0.0 8.5 5.8 0.0 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXT02324.1 - 0.0072 16.3 0.2 0.59 10.1 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 KXT02324.1 - 0.023 14.0 0.0 0.24 10.7 0.0 2.5 2 1 1 3 3 3 0 Flavin containing amine oxidoreductase Thi4 PF01946.17 KXT02324.1 - 0.065 12.5 0.0 5.4 6.2 0.0 2.7 3 0 0 3 3 3 0 Thi4 family RNA_pol_Rpb2_6 PF00562.28 KXT02325.1 - 2.6e-113 379.0 0.8 3.5e-113 378.6 0.8 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KXT02325.1 - 1.1e-29 103.4 0.0 1.9e-29 102.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 KXT02325.1 - 1.1e-28 99.2 0.0 3.8e-28 97.5 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 KXT02325.1 - 2.4e-27 94.7 0.0 4.9e-27 93.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.14 KXT02325.1 - 5.8e-25 88.0 0.0 1.1e-24 87.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KXT02325.1 - 1.4e-15 57.4 0.0 1e-14 54.6 0.0 2.3 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 MFS_1 PF07690.16 KXT02326.1 - 7.3e-15 54.7 43.3 1.2e-14 54.0 40.3 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily AMP-binding PF00501.28 KXT02327.1 - 4e-64 216.8 0.0 5.4e-64 216.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXT02327.1 - 3.1e-08 34.5 0.0 8.6e-08 33.1 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 KXT02327.1 - 1.1e-06 28.8 0.2 3.1e-06 27.4 0.2 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Condensation PF00668.20 KXT02327.1 - 3.7e-06 25.9 0.0 1.2e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 Condensation domain DUF2619 PF10942.8 KXT02327.1 - 0.11 12.6 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2619) zf-RING_2 PF13639.6 KXT02328.1 - 3.7e-08 33.6 9.2 7.2e-08 32.6 9.2 1.5 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 KXT02328.1 - 1.6e-06 28.2 6.4 3.7e-06 27.0 6.4 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 KXT02328.1 - 1.3e-05 25.2 2.9 2.9e-05 24.0 2.9 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KXT02328.1 - 0.0016 18.7 8.0 0.0037 17.5 8.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING-like PF08746.11 KXT02328.1 - 0.0021 18.3 7.1 0.0042 17.3 7.1 1.5 1 0 0 1 1 1 1 RING-like domain RINGv PF12906.7 KXT02328.1 - 0.0024 18.0 6.0 0.0061 16.7 6.0 1.8 1 0 0 1 1 1 1 RING-variant domain zf-C3HC4_2 PF13923.6 KXT02328.1 - 0.0051 16.6 8.7 0.012 15.4 8.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXT02328.1 - 0.0055 16.5 10.0 0.011 15.6 10.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.22 KXT02328.1 - 0.0091 15.9 6.0 0.02 14.8 6.0 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_4 PF14570.6 KXT02328.1 - 0.012 15.4 8.5 0.2 11.4 1.5 2.4 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 KXT02328.1 - 0.016 14.9 4.9 0.032 13.9 4.9 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type NIT PF08376.10 KXT02328.1 - 0.022 15.3 0.7 0.022 15.3 0.7 2.9 3 1 0 3 3 2 0 Nitrate and nitrite sensing zf-RING_9 PF13901.6 KXT02328.1 - 0.034 14.1 6.5 0.11 12.4 6.5 1.9 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon zf-C3HC4_3 PF13920.6 KXT02328.1 - 0.28 11.1 8.2 0.71 9.8 8.2 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn-C2H2_12 PF18112.1 KXT02328.1 - 0.4 11.2 6.4 3.5 8.2 2.1 2.6 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-RING_11 PF17123.5 KXT02328.1 - 0.79 9.5 3.5 1.6 8.5 3.5 1.6 1 0 0 1 1 1 0 RING-like zinc finger PHD PF00628.29 KXT02328.1 - 1.5 8.8 7.3 2.7 7.9 7.3 1.4 1 0 0 1 1 1 0 PHD-finger Prok-RING_4 PF14447.6 KXT02328.1 - 7.9 6.4 10.0 82 3.2 10.0 2.4 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KXT02328.1 - 9.1 6.4 6.5 27 4.9 6.5 1.9 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_1 PF14446.6 KXT02328.1 - 9.8 6.2 6.2 41 4.2 6.2 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 HET PF06985.11 KXT02330.1 - 3.4e-33 115.0 0.0 8e-33 113.8 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Transp_cyt_pur PF02133.15 KXT02331.1 - 6.6e-87 292.1 34.4 8.2e-87 291.8 34.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Transp_cyt_pur PF02133.15 KXT02332.1 - 6.6e-87 292.1 34.4 8.2e-87 291.8 34.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Ank_4 PF13637.6 KXT02333.1 - 0.00021 21.8 0.3 0.17 12.5 0.0 2.7 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXT02333.1 - 0.0021 18.6 0.3 0.092 13.3 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Methyltransf_2 PF00891.18 KXT02333.1 - 0.017 14.5 0.0 0.034 13.4 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase domain Gti1_Pac2 PF09729.9 KXT02334.1 - 7.9e-44 149.9 9.9 7.5e-38 130.4 0.3 3.2 2 1 1 3 3 3 2 Gti1/Pac2 family DUF908 PF06012.12 KXT02334.1 - 4.8 6.5 7.5 8.1 5.7 7.5 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Hid1 PF12722.7 KXT02335.1 - 0.0056 14.9 15.4 0.007 14.6 15.4 1.1 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.16 KXT02335.1 - 0.0059 16.7 9.4 0.0094 16.0 9.4 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.22 KXT02335.1 - 0.013 14.7 0.4 0.019 14.2 0.4 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1282 PF06930.12 KXT02335.1 - 0.042 13.6 0.1 0.058 13.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) Membralin PF09746.9 KXT02335.1 - 1.7 7.6 6.8 2.2 7.2 6.8 1.2 1 0 0 1 1 1 0 Tumour-associated protein SLC12 PF03522.15 KXT02335.1 - 4.3 6.3 20.0 6.3 5.7 20.0 1.2 1 0 0 1 1 1 0 Solute carrier family 12 LAP1C PF05609.12 KXT02335.1 - 8.3 5.4 22.0 12 4.9 22.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Peptidase_S64 PF08192.11 KXT02335.1 - 9.4 4.6 11.2 13 4.1 11.2 1.3 1 0 0 1 1 1 0 Peptidase family S64 SGL PF08450.12 KXT02336.1 - 1.2e-27 97.1 0.1 1e-25 90.8 0.0 2.4 1 1 1 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region Fungal_trans PF04082.18 KXT02336.1 - 0.00012 21.2 0.1 0.00033 19.8 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Arylesterase PF01731.20 KXT02336.1 - 0.0023 18.1 0.0 0.0073 16.5 0.0 1.8 1 0 0 1 1 1 1 Arylesterase Peptidase_M43 PF05572.13 KXT02337.1 - 3.3e-09 36.8 0.0 6.8e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 KXT02337.1 - 4.2e-05 24.1 0.0 0.00044 20.8 0.0 2.2 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KXT02337.1 - 0.00027 21.2 0.0 0.00073 19.7 0.0 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M10 PF00413.24 KXT02337.1 - 0.025 14.4 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 Matrixin MFS_1 PF07690.16 KXT02338.1 - 1.9e-50 171.8 32.4 1.9e-50 171.8 32.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXT02338.1 - 1e-13 51.0 10.6 1e-13 51.0 10.6 2.5 1 1 1 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KXT02338.1 - 5.8e-06 25.0 4.0 9.2e-06 24.4 4.0 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) SpoIIIAC PF06686.11 KXT02338.1 - 0.57 10.4 0.1 0.57 10.4 0.1 3.4 4 0 0 4 4 4 0 Stage III sporulation protein AC/AD protein family MFS_1 PF07690.16 KXT02339.1 - 1.9e-50 171.8 32.4 1.9e-50 171.8 32.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXT02339.1 - 1e-13 51.0 10.6 1e-13 51.0 10.6 2.5 1 1 1 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KXT02339.1 - 5.8e-06 25.0 4.0 9.2e-06 24.4 4.0 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) SpoIIIAC PF06686.11 KXT02339.1 - 0.57 10.4 0.1 0.57 10.4 0.1 3.4 4 0 0 4 4 4 0 Stage III sporulation protein AC/AD protein family adh_short PF00106.25 KXT02340.1 - 2.8e-40 137.9 0.3 3.7e-40 137.5 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT02340.1 - 4.3e-29 101.7 0.1 6e-29 101.2 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KXT02340.1 - 7.7e-08 32.0 0.0 3.6e-07 29.8 0.0 1.9 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 KXT02340.1 - 1e-07 32.0 0.2 1.7e-07 31.3 0.2 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KXT02340.1 - 4e-06 26.8 0.0 8.4e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXT02340.1 - 0.0017 17.9 0.0 0.0038 16.7 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KXT02340.1 - 0.0023 17.5 0.0 0.0048 16.5 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family F420_oxidored PF03807.17 KXT02340.1 - 0.017 15.7 0.0 0.058 14.0 0.0 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KXT02340.1 - 0.031 13.6 0.0 0.064 12.6 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 KXT02340.1 - 0.073 12.2 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.8 KXT02340.1 - 0.11 12.2 0.1 0.26 11.1 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase zf-met2 PF12907.7 KXT02341.1 - 2.8e-11 43.4 5.4 4.5e-11 42.7 5.4 1.3 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 KXT02341.1 - 0.00028 21.7 9.5 0.00028 21.7 9.5 1.7 2 0 0 2 2 2 1 4F5 protein family zf-C2H2_11 PF16622.5 KXT02341.1 - 0.089 12.6 2.3 0.17 11.7 2.3 1.5 1 0 0 1 1 1 0 zinc-finger C2H2-type Peptidase_S10 PF00450.22 KXT02342.1 - 1.4e-84 284.9 3.5 9.2e-84 282.3 3.5 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase RNA_pol_Rpb1_5 PF04998.17 KXT02343.1 - 2.2e-87 292.9 0.1 4.7e-87 291.8 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KXT02343.1 - 5.2e-68 228.5 0.0 9.7e-68 227.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KXT02343.1 - 2.3e-32 112.1 0.0 5.7e-32 110.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 KXT02343.1 - 3.1e-31 108.9 0.0 7.2e-30 104.4 0.0 3.0 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 KXT02343.1 - 4.3e-18 65.2 0.0 1.3e-17 63.7 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Glyco_hydro_65C PF03633.15 KXT02344.1 - 0.012 15.4 2.2 3.7 7.5 0.1 3.0 3 0 0 3 3 3 0 Glycosyl hydrolase family 65, C-terminal domain IL3Ra_N PF18611.1 KXT02344.1 - 5.3 7.1 11.7 21 5.2 1.5 3.5 3 0 0 3 3 3 0 IL-3 receptor alpha chain N-terminal domain Tafi-CsgC PF10610.9 KXT02344.1 - 8.4 6.7 13.6 31 4.9 0.9 3.7 3 0 0 3 3 3 0 Thin aggregative fimbriae synthesis protein Aldedh PF00171.22 KXT02345.1 - 1.8e-127 425.7 0.0 2e-127 425.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ATG16 PF08614.11 KXT02346.1 - 0.018 15.3 0.2 0.018 15.3 0.2 11.5 8 4 3 12 12 12 0 Autophagy protein 16 (ATG16) Tup_N PF08581.10 KXT02346.1 - 0.024 14.9 45.5 0.28 11.5 0.1 12.8 11 4 2 13 13 13 0 Tup N-terminal NTP_transf_2 PF01909.23 KXT02346.1 - 0.7 10.2 3.5 4.1 7.8 0.3 3.3 2 0 0 2 2 2 0 Nucleotidyltransferase domain HALZ PF02183.18 KXT02346.1 - 0.84 9.9 13.0 0.037 14.2 1.6 4.9 5 0 0 5 5 5 0 Homeobox associated leucine zipper Iron_permease PF04120.12 KXT02346.1 - 7.9 6.3 7.2 11 5.9 2.4 3.8 2 1 0 2 2 2 0 Low affinity iron permease F-box PF00646.33 KXT02347.1 - 0.0007 19.4 0.1 0.0014 18.5 0.1 1.4 1 0 0 1 1 1 1 F-box domain Phage_Gp23 PF10669.9 KXT02347.1 - 0.41 11.0 2.4 0.7 10.2 2.4 1.4 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) SIMPL PF04402.14 KXT02348.1 - 7.7e-23 82.0 0.0 8.7e-23 81.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) DUF2335 PF10097.9 KXT02349.1 - 0.068 13.1 0.7 0.18 11.8 0.7 1.8 1 0 0 1 1 1 0 Predicted membrane protein (DUF2335) Seryl_tRNA_N PF02403.22 KXT02349.1 - 2.3 8.5 7.9 2.4 8.4 0.8 2.7 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain EZH2_N PF18601.1 KXT02352.1 - 0.085 13.2 0.1 10 6.5 0.0 2.7 3 0 0 3 3 3 0 EZH2 N-terminal domain WavE PF07507.11 KXT02354.1 - 0.0003 20.1 0.0 0.00039 19.7 0.0 1.1 1 0 0 1 1 1 1 WavE lipopolysaccharide synthesis DUF3085 PF11284.8 KXT02355.1 - 0.085 13.2 0.0 0.14 12.4 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3085) SNF2_N PF00176.23 KXT02356.1 - 1.4e-57 195.0 0.0 2.2e-57 194.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 KXT02356.1 - 3e-54 184.0 2.1 1.4e-53 181.8 2.9 1.7 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.31 KXT02356.1 - 7.5e-16 58.5 0.0 1.7e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXT02356.1 - 3e-06 27.3 0.0 6e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KXT02356.1 - 0.0029 16.8 0.0 0.02 14.1 0.0 2.3 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 MFS_1 PF07690.16 KXT02357.1 - 1.4e-40 139.4 44.6 1.4e-40 139.4 44.6 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXT02357.1 - 1.1e-14 53.9 25.9 1.1e-14 53.9 25.9 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXT02357.1 - 2.9e-11 42.9 11.8 2.9e-11 42.9 11.8 2.9 1 1 0 2 2 2 1 Sugar (and other) transporter DUF5337 PF17272.2 KXT02357.1 - 0.0081 16.0 1.3 0.041 13.7 1.3 2.2 1 0 0 1 1 1 1 Family of unknown function (DUF5337) CH PF00307.31 KXT02358.1 - 1.2e-69 231.4 0.0 5.4e-18 65.2 0.0 4.3 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 KXT02358.1 - 0.00011 22.6 1.2 0.00049 20.5 0.2 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KXT02358.1 - 0.0067 15.9 1.5 1.9 8.2 0.2 3.4 3 0 0 3 3 3 1 EF hand CAMSAP_CH PF11971.8 KXT02358.1 - 0.019 14.8 0.0 3.9 7.4 0.0 3.4 4 0 0 4 4 4 0 CAMSAP CH domain EF-hand_6 PF13405.6 KXT02358.1 - 0.034 14.1 1.0 1.1 9.4 0.2 2.7 2 0 0 2 2 2 0 EF-hand domain F-box PF00646.33 KXT02359.1 - 1.6e-05 24.7 0.0 3.6e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXT02359.1 - 9.1e-05 22.3 0.5 0.00022 21.0 0.1 1.9 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 KXT02359.1 - 0.062 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 F-box Hce2 PF14856.6 KXT02360.1 - 3.6e-22 78.6 0.8 9.1e-22 77.3 0.8 1.7 1 1 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor HemS PF05171.12 KXT02360.1 - 0.094 12.7 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Haemin-degrading HemS.ChuX domain HCMV_UL124 PF17609.2 KXT02361.1 - 0.097 12.9 0.5 0.31 11.2 0.0 1.9 2 1 0 2 2 2 0 Family of unknown function Amidohydro_2 PF04909.14 KXT02362.1 - 5.1e-27 95.4 0.0 6.9e-27 95.0 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase RNA_pol_Rpb5_C PF01191.19 KXT02364.1 - 1e-30 105.4 0.1 1.9e-30 104.5 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 KXT02364.1 - 3.2e-26 91.7 0.0 4.9e-26 91.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Sialidase PF02973.16 KXT02364.1 - 0.067 12.7 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Sialidase, N-terminal domain Sld3_N PF18523.1 KXT02364.1 - 0.071 13.2 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 Sld3 N-terminal domain Sof1 PF04158.14 KXT02364.1 - 0.12 12.7 0.1 0.25 11.7 0.1 1.5 1 0 0 1 1 1 0 Sof1-like domain partial_CstF PF15861.5 KXT02364.1 - 0.15 11.9 0.2 0.29 10.9 0.2 1.5 1 0 0 1 1 1 0 Partial cleavage stimulation factor domain PRP3 PF08572.10 KXT02365.1 - 2.4e-67 227.0 11.2 2.4e-67 227.0 11.2 2.5 2 1 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 KXT02365.1 - 2.3e-46 157.5 1.3 3.2e-46 157.1 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) GET2 PF08690.10 KXT02365.1 - 0.0055 16.4 5.8 0.0055 16.4 5.8 2.8 3 0 0 3 3 3 1 GET complex subunit GET2 COQ9 PF08511.11 KXT02366.1 - 2.2e-30 104.2 0.1 9.3e-30 102.2 0.1 2.0 2 0 0 2 2 2 1 COQ9 2OG-FeII_Oxy_3 PF13640.6 KXT02366.1 - 1.3e-08 35.6 0.0 2.7e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily OST3_OST6 PF04756.13 KXT02367.1 - 1.6e-108 362.5 0.0 1.9e-108 362.3 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family HXXEE PF13787.6 KXT02367.1 - 0.0054 17.5 1.2 0.0094 16.8 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function with HXXEE motif Thioredoxin PF00085.20 KXT02367.1 - 0.088 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin DUF2232 PF09991.9 KXT02367.1 - 0.31 10.2 9.0 0.045 12.9 5.2 1.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) CPBP PF02517.16 KXT02367.1 - 0.41 11.1 3.6 1.9 8.9 3.8 2.0 1 1 1 2 2 2 0 CPBP intramembrane metalloprotease FA_desaturase PF00487.24 KXT02367.1 - 0.43 10.4 6.9 0.053 13.4 1.8 1.9 1 1 1 2 2 2 0 Fatty acid desaturase MerC PF03203.14 KXT02367.1 - 2.2 8.8 6.7 25 5.3 2.6 2.4 2 0 0 2 2 2 0 MerC mercury resistance protein QCR10 PF09796.9 KXT02367.1 - 8.1 6.6 10.0 8.1 6.6 0.2 3.6 2 2 2 4 4 4 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) OST3_OST6 PF04756.13 KXT02368.1 - 1.6e-108 362.5 0.0 1.9e-108 362.3 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family HXXEE PF13787.6 KXT02368.1 - 0.0054 17.5 1.2 0.0094 16.8 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function with HXXEE motif Thioredoxin PF00085.20 KXT02368.1 - 0.088 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin DUF2232 PF09991.9 KXT02368.1 - 0.31 10.2 9.0 0.045 12.9 5.2 1.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) CPBP PF02517.16 KXT02368.1 - 0.41 11.1 3.6 1.9 8.9 3.8 2.0 1 1 1 2 2 2 0 CPBP intramembrane metalloprotease FA_desaturase PF00487.24 KXT02368.1 - 0.43 10.4 6.9 0.053 13.4 1.8 1.9 1 1 1 2 2 2 0 Fatty acid desaturase MerC PF03203.14 KXT02368.1 - 2.2 8.8 6.7 25 5.3 2.6 2.4 2 0 0 2 2 2 0 MerC mercury resistance protein QCR10 PF09796.9 KXT02368.1 - 8.1 6.6 10.0 8.1 6.6 0.2 3.6 2 2 2 4 4 4 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) TPT PF03151.16 KXT02369.1 - 5.1e-22 78.6 11.2 1.2e-21 77.3 11.2 1.5 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KXT02369.1 - 4.2e-06 27.0 33.8 0.00042 20.5 3.5 2.8 3 0 0 3 3 3 2 EamA-like transporter family Caldesmon PF02029.15 KXT02369.1 - 0.27 10.0 9.0 0.51 9.0 9.0 1.4 1 0 0 1 1 1 0 Caldesmon Bap31_Bap29_C PF18035.1 KXT02369.1 - 0.87 9.6 5.0 0.17 11.9 0.8 1.9 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain SRF-TF PF00319.18 KXT02370.1 - 0.15 11.6 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 SRF-type transcription factor (DNA-binding and dimerisation domain) PhoR PF11808.8 KXT02373.1 - 0.069 13.6 0.2 0.11 12.9 0.2 1.2 1 0 0 1 1 1 0 Phosphate regulon sensor protein PhoR FUSC_2 PF13515.6 KXT02374.1 - 9.1e-29 100.2 6.5 9.1e-29 100.2 6.5 2.5 2 0 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.8 KXT02374.1 - 2.5e-10 39.8 22.6 1.4e-08 34.1 10.7 3.6 3 1 0 3 3 3 2 Aluminium activated malate transporter FUSC PF04632.12 KXT02374.1 - 7.8e-05 21.4 7.5 0.058 11.9 2.8 3.4 3 0 0 3 3 3 3 Fusaric acid resistance protein family ArAE_2 PF10334.9 KXT02374.1 - 0.0059 16.5 0.1 0.025 14.4 0.0 2.0 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 Ank_2 PF12796.7 KXT02375.1 - 1.7e-19 70.1 6.4 4.5e-09 36.8 0.4 4.2 1 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXT02375.1 - 1.2e-13 51.3 1.3 2.6e-07 31.1 0.1 4.3 3 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXT02375.1 - 3.4e-12 45.4 6.4 0.016 15.7 0.0 6.4 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 KXT02375.1 - 3.9e-11 43.0 0.4 1.6e-06 28.3 0.1 4.1 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 KXT02375.1 - 2.2e-08 34.2 14.0 0.14 12.6 0.1 5.8 6 0 0 6 6 6 3 Ankyrin repeat Ank_2 PF12796.7 KXT02376.1 - 1.7e-19 70.1 6.4 4.5e-09 36.8 0.4 4.2 1 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXT02376.1 - 1.2e-13 51.3 1.3 2.6e-07 31.1 0.1 4.3 3 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXT02376.1 - 3.4e-12 45.4 6.4 0.016 15.7 0.0 6.4 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 KXT02376.1 - 3.9e-11 43.0 0.4 1.6e-06 28.3 0.1 4.1 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 KXT02376.1 - 2.2e-08 34.2 14.0 0.14 12.6 0.1 5.8 6 0 0 6 6 6 3 Ankyrin repeat NifU_N PF01592.16 KXT02377.1 - 1.8e-54 183.3 0.1 2.6e-54 182.8 0.1 1.2 1 0 0 1 1 1 1 NifU-like N terminal domain TSCPD PF12637.7 KXT02377.1 - 0.098 12.9 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 TSCPD domain RPN6_N PF18055.1 KXT02378.1 - 5.4e-45 152.5 0.7 1.4e-44 151.1 0.1 2.1 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 KXT02378.1 - 1e-18 67.8 0.7 2.5e-18 66.5 0.2 2.0 2 0 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 KXT02378.1 - 2.1e-12 46.5 0.3 4.8e-12 45.4 0.3 1.7 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_MalT PF17874.1 KXT02378.1 - 7e-05 22.4 4.7 0.0022 17.5 1.0 3.2 1 1 1 3 3 3 1 MalT-like TPR region NepR PF18557.1 KXT02378.1 - 0.0065 16.1 0.0 0.018 14.7 0.0 1.8 1 0 0 1 1 1 1 Anti-sigma factor NepR TPR_12 PF13424.6 KXT02378.1 - 0.012 15.9 15.1 0.56 10.5 0.3 5.3 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.6 KXT02378.1 - 0.054 14.0 5.8 7.9 7.1 0.1 4.9 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 KXT02378.1 - 0.061 13.4 6.3 11 6.3 0.0 4.5 4 1 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXT02378.1 - 0.074 12.9 3.0 21 5.2 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat DDRGK PF09756.9 KXT02378.1 - 0.13 11.8 3.4 0.19 11.3 0.1 2.2 2 0 0 2 2 2 0 DDRGK domain SbsC_C PF18058.1 KXT02378.1 - 0.18 12.0 0.0 0.18 12.0 0.0 2.8 3 0 0 3 3 3 0 SbsC C-terminal domain TPR_16 PF13432.6 KXT02378.1 - 0.26 12.0 6.8 7.7 7.3 0.0 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_3 PF07720.12 KXT02378.1 - 0.26 11.3 5.3 3.9 7.6 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXT02378.1 - 6.2 7.2 11.5 1.2e+02 3.2 0.8 6.0 5 1 2 7 7 7 0 Tetratricopeptide repeat Ogr_Delta PF04606.12 KXT02379.1 - 0.11 12.5 0.1 0.22 11.5 0.1 1.4 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger IBR PF01485.21 KXT02380.1 - 3.5e-21 75.2 50.1 1.7e-11 44.1 9.2 4.6 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain W2 PF02020.18 KXT02380.1 - 7e-11 42.1 6.7 7e-11 42.1 6.7 3.1 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 KXT02380.1 - 3.1e-07 29.9 8.8 0.00014 21.4 0.7 3.3 1 1 3 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KXT02380.1 - 0.00014 22.3 0.0 0.00034 21.0 0.0 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain zf-C3HC4 PF00097.25 KXT02380.1 - 0.00025 20.8 4.8 0.00025 20.8 4.8 4.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXT02380.1 - 0.00066 20.0 3.7 0.00066 20.0 3.7 4.1 2 1 1 3 3 3 1 Ring finger domain NTP_transferase PF00483.23 KXT02380.1 - 0.0059 16.2 0.0 0.014 14.9 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.6 KXT02380.1 - 0.13 12.1 5.2 0.41 10.4 3.1 2.5 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase zf-C3HC4_2 PF13923.6 KXT02380.1 - 8.3 6.4 43.7 0.016 15.0 4.4 4.5 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Lactamase_B PF00753.27 KXT02381.1 - 6.4e-08 32.8 0.1 1.1e-07 32.1 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXT02381.1 - 0.01 15.4 0.0 0.024 14.2 0.0 1.7 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KXT02381.1 - 0.012 15.5 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain AAA PF00004.29 KXT02382.1 - 1.6e-41 141.8 0.0 2.6e-14 53.8 0.0 6.7 6 0 0 6 6 6 4 ATPase family associated with various cellular activities (AAA) AAA_12 PF13087.6 KXT02382.1 - 6e-39 133.7 0.0 1.8e-38 132.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KXT02382.1 - 3.6e-25 89.2 0.0 3.6e-25 89.2 0.0 7.0 6 1 0 6 6 5 2 AAA domain AAA_30 PF13604.6 KXT02382.1 - 3.9e-19 69.1 1.1 0.00044 20.0 0.0 6.1 6 0 0 6 6 5 4 AAA domain AAA_19 PF13245.6 KXT02382.1 - 3.5e-18 66.3 0.0 2.7e-09 37.5 0.0 5.0 4 1 0 4 4 4 2 AAA domain AAA_lid_6 PF17866.1 KXT02382.1 - 4.5e-15 55.6 11.8 1.1e-06 28.7 0.7 4.6 4 0 0 4 4 3 2 AAA lid domain AAA_5 PF07728.14 KXT02382.1 - 6e-14 52.2 0.8 0.0093 16.0 0.0 5.6 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXT02382.1 - 5.2e-11 43.0 15.6 0.33 11.2 0.5 9.0 7 3 0 7 7 5 4 AAA domain AAA_18 PF13238.6 KXT02382.1 - 2.8e-09 37.6 2.9 0.1 13.2 0.0 5.4 4 0 0 4 4 4 1 AAA domain Mg_chelatase PF01078.21 KXT02382.1 - 5.1e-09 35.8 0.5 0.1 12.0 0.0 4.6 4 0 0 4 4 4 2 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 KXT02382.1 - 5.4e-09 36.0 0.1 0.08 12.7 0.0 4.8 4 1 0 4 4 4 2 Holliday junction DNA helicase RuvB P-loop domain Viral_helicase1 PF01443.18 KXT02382.1 - 7.7e-09 35.6 0.1 0.13 11.9 0.0 5.9 6 0 0 6 6 6 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 KXT02382.1 - 6.7e-08 32.7 0.0 0.00023 21.2 0.0 4.6 5 0 0 5 5 5 1 Type III restriction enzyme, res subunit AAA_24 PF13479.6 KXT02382.1 - 3.9e-07 30.0 4.8 1.1 8.9 0.1 5.4 5 0 0 5 5 5 3 AAA domain RNA_helicase PF00910.22 KXT02382.1 - 6.7e-07 29.7 1.3 3.2 8.2 0.0 5.0 5 0 0 5 5 4 2 RNA helicase IstB_IS21 PF01695.17 KXT02382.1 - 1.8e-06 27.8 0.1 6.1 6.5 0.0 4.7 4 0 0 4 4 4 0 IstB-like ATP binding protein Torsin PF06309.11 KXT02382.1 - 2.2e-06 27.8 0.1 0.76 9.9 0.0 4.5 4 0 0 4 4 4 1 Torsin AAA_7 PF12775.7 KXT02382.1 - 4.6e-05 23.0 0.1 5.3 6.5 0.0 4.7 4 0 0 4 4 4 0 P-loop containing dynein motor region AAA_16 PF13191.6 KXT02382.1 - 6.3e-05 23.4 17.8 1.3 9.3 0.0 6.8 7 0 0 7 7 6 2 AAA ATPase domain DUF2075 PF09848.9 KXT02382.1 - 0.00012 21.5 10.0 0.0043 16.4 0.0 6.6 6 1 0 6 6 6 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 KXT02382.1 - 0.00017 21.1 1.3 4 6.8 0.0 4.4 4 0 0 4 4 4 1 PhoH-like protein AAA_25 PF13481.6 KXT02382.1 - 0.0003 20.4 2.3 1.5 8.3 0.0 5.4 4 0 0 4 4 4 1 AAA domain TniB PF05621.11 KXT02382.1 - 0.00065 19.2 0.1 2.5 7.5 0.0 4.9 5 1 1 6 6 5 1 Bacterial TniB protein Adeno_IVa2 PF02456.15 KXT02382.1 - 0.00079 18.3 0.0 0.0017 17.2 0.0 1.4 1 0 0 1 1 1 1 Adenovirus IVa2 protein ATPase PF06745.13 KXT02382.1 - 0.0019 17.6 1.2 2.5 7.4 0.0 4.1 4 0 0 4 4 4 1 KaiC Rad17 PF03215.15 KXT02382.1 - 0.0028 17.6 0.2 3.2 7.6 0.0 3.6 4 0 0 4 4 4 1 Rad17 P-loop domain AAA_33 PF13671.6 KXT02382.1 - 0.0044 17.2 20.8 0.39 10.9 0.0 6.4 7 0 0 7 7 4 2 AAA domain AAA_14 PF13173.6 KXT02382.1 - 0.0079 16.2 0.0 13 5.9 0.0 3.9 4 0 0 4 4 3 0 AAA domain TsaE PF02367.17 KXT02382.1 - 0.033 14.2 1.0 8.4 6.4 0.0 3.8 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KXT02382.1 - 0.079 12.9 3.3 58 3.6 0.0 4.8 4 0 0 4 4 4 0 NACHT domain SRP54 PF00448.22 KXT02382.1 - 0.1 12.3 3.3 2.6 7.6 0.0 3.9 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain Guanylate_cyc_2 PF09778.9 KXT02382.1 - 0.12 11.7 0.0 16 4.8 0.0 2.5 2 0 0 2 2 2 0 Guanylylate cyclase UvrD_C_2 PF13538.6 KXT02382.1 - 0.14 12.0 0.0 0.44 10.4 0.0 1.9 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain ABC_tran PF00005.27 KXT02382.1 - 0.21 12.1 8.4 42 4.6 0.0 5.0 5 0 0 5 5 4 0 ABC transporter ADK PF00406.22 KXT02382.1 - 0.31 11.1 2.7 85 3.2 0.0 4.6 4 0 0 4 4 4 0 Adenylate kinase NTPase_1 PF03266.15 KXT02382.1 - 0.49 10.3 3.5 64 3.4 0.0 4.0 4 0 0 4 4 4 0 NTPase AAA_28 PF13521.6 KXT02382.1 - 0.57 10.4 19.3 2.3 8.4 0.0 6.1 6 0 0 6 6 5 0 AAA domain Helicase_RecD PF05127.14 KXT02382.1 - 0.58 10.0 4.0 0.88 9.4 0.0 3.5 4 0 0 4 4 3 0 Helicase TFIIA PF03153.13 KXT02382.1 - 2.5 8.0 35.2 0.29 11.1 13.9 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit AAA_17 PF13207.6 KXT02382.1 - 5.3 7.5 19.3 4.4 7.7 0.0 5.6 6 0 0 6 6 4 0 AAA domain Zn_clus PF00172.18 KXT02383.1 - 3.5e-08 33.4 9.3 7.4e-08 32.4 9.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXT02383.1 - 1.5e-05 24.2 0.0 4e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Pyr_redox_3 PF13738.6 KXT02385.1 - 2.1e-15 56.8 0.0 6.7e-14 51.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KXT02385.1 - 2e-14 53.0 0.0 3.5e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KXT02385.1 - 1.2e-09 37.7 0.1 8.1e-08 31.8 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KXT02385.1 - 3.2e-09 36.4 0.0 4.2e-07 29.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXT02385.1 - 9.1e-06 25.8 0.0 0.00061 20.0 0.0 3.0 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXT02385.1 - 0.00027 20.6 0.8 0.15 11.6 0.5 2.8 2 1 1 3 3 3 2 FAD dependent oxidoreductase Shikimate_DH PF01488.20 KXT02385.1 - 0.0014 18.7 0.0 0.021 14.9 0.0 2.3 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 KXT02385.1 - 0.0078 15.3 0.0 0.018 14.1 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain 2-Hacid_dh_C PF02826.19 KXT02385.1 - 0.48 9.8 1.7 1.2 8.4 0.0 2.4 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Spem1 PF15670.5 KXT02386.1 - 0.072 12.7 2.0 0.12 11.9 2.0 1.3 1 0 0 1 1 1 0 Spermatid maturation protein 1 Dioxygenase_C PF00775.21 KXT02388.1 - 1.1e-47 161.8 0.1 1.4e-47 161.5 0.1 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KXT02388.1 - 1.6e-28 98.4 0.4 2.5e-28 97.7 0.4 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 KXT02388.1 - 8.5e-08 32.4 0.1 4.8e-07 30.0 0.0 2.2 3 0 0 3 3 3 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 KXT02388.1 - 0.011 15.7 0.1 2 8.4 0.0 2.9 3 0 0 3 3 3 0 CarboxypepD_reg-like domain SpaA PF17802.1 KXT02388.1 - 0.087 13.2 0.0 0.23 11.8 0.0 1.7 2 0 0 2 2 2 0 Prealbumin-like fold domain Vac14_Fig4_bd PF11916.8 KXT02389.1 - 5.2e-79 264.1 7.5 1e-78 263.1 7.5 1.5 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 KXT02389.1 - 2e-45 153.3 0.8 4.9e-42 142.5 0.1 4.2 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KXT02389.1 - 1.3e-08 35.1 2.4 0.0014 19.1 0.1 4.8 4 0 0 4 4 4 2 HEAT-like repeat HEAT PF02985.22 KXT02389.1 - 8.9e-07 28.7 3.5 0.0012 18.9 0.0 6.0 7 0 0 7 7 6 1 HEAT repeat Cnd1 PF12717.7 KXT02389.1 - 7.9e-06 26.0 3.9 0.037 14.1 0.9 3.7 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KXT02389.1 - 0.00013 22.3 5.8 0.13 12.7 0.1 5.1 6 0 0 6 6 6 1 HEAT repeats UME PF08064.13 KXT02389.1 - 0.0021 17.9 0.5 0.91 9.5 0.1 3.1 3 0 0 3 3 3 1 UME (NUC010) domain Dopey_N PF04118.14 KXT02389.1 - 0.034 13.3 2.1 1.2 8.2 0.2 3.2 3 0 0 3 3 3 0 Dopey, N-terminal Arm PF00514.23 KXT02389.1 - 0.052 13.6 1.2 15 5.8 0.0 4.8 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat ParcG PF10274.9 KXT02389.1 - 0.12 12.5 0.9 14 5.8 0.0 3.0 3 0 0 3 3 3 0 Parkin co-regulated protein DUF2052 PF09747.9 KXT02389.1 - 0.14 12.2 9.2 0.035 14.2 4.0 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Lipase_GDSL PF00657.22 KXT02390.1 - 8.1e-08 32.5 0.1 1e-07 32.1 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KXT02390.1 - 1.5e-06 28.7 2.9 2.8e-06 27.8 2.9 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family AMP-binding PF00501.28 KXT02391.1 - 4.2e-74 249.7 0.0 5.3e-74 249.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXT02391.1 - 4.9e-17 62.7 0.0 1e-16 61.7 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KXT02391.1 - 1.7e-12 47.0 3.6 1.7e-12 47.0 3.6 2.2 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus Stn1_C PF12659.7 KXT02391.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Telomere capping C-terminal wHTH CK1gamma_C PF12605.8 KXT02392.1 - 0.1 13.8 0.1 7.3 7.8 0.0 2.3 2 0 0 2 2 2 0 Casein kinase 1 gamma C terminal RrnaAD PF00398.20 KXT02394.1 - 9.5e-61 205.2 0.0 1.5e-60 204.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 KXT02394.1 - 2.8e-07 31.2 0.0 6.3e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXT02394.1 - 6.5e-05 22.8 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXT02394.1 - 0.0002 22.1 0.0 0.0021 18.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXT02394.1 - 0.0002 22.0 0.0 0.00043 20.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KXT02394.1 - 0.00088 19.1 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 KXT02394.1 - 0.0027 17.5 0.0 0.005 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXT02394.1 - 0.0097 15.5 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 KXT02394.1 - 0.011 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein AAA_lid_4 PF17864.1 KXT02394.1 - 0.011 15.5 0.1 0.023 14.4 0.1 1.5 1 0 0 1 1 1 0 RuvB AAA lid domain CMAS PF02353.20 KXT02394.1 - 0.04 13.2 0.0 0.066 12.5 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 KXT02394.1 - 0.079 12.3 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family NodS PF05401.11 KXT02394.1 - 0.15 11.7 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_28 PF02636.17 KXT02394.1 - 0.16 11.6 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DREV PF05219.12 KXT02394.1 - 0.19 10.8 0.0 0.34 10.0 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Amidohydro_2 PF04909.14 KXT02395.1 - 9.8e-33 114.2 0.0 1.3e-32 113.8 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase FAD_binding_3 PF01494.19 KXT02396.1 - 7.5e-20 71.5 0.1 1.7e-19 70.3 0.1 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXT02396.1 - 5.2e-07 29.2 0.7 1.2e-06 27.9 0.7 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXT02396.1 - 7.1e-07 28.6 1.7 0.0015 17.7 1.6 2.2 1 1 1 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KXT02396.1 - 8.8e-07 29.1 0.4 1.9e-06 28.0 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KXT02396.1 - 5.5e-06 25.7 0.1 8.1e-06 25.1 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KXT02396.1 - 1.5e-05 24.8 6.1 2.9e-05 23.8 4.0 2.1 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXT02396.1 - 0.00013 22.4 1.2 0.0081 16.7 0.7 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXT02396.1 - 0.00034 20.1 0.1 0.00048 19.6 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KXT02396.1 - 0.0053 15.9 1.8 0.037 13.1 0.5 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 KXT02396.1 - 0.0075 15.0 1.8 0.031 13.0 1.8 1.8 1 1 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 KXT02396.1 - 0.008 15.5 1.0 0.67 9.2 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KXT02396.1 - 0.044 13.1 0.2 2.1 7.5 0.1 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_Gly3P_dh_N PF01210.23 KXT02396.1 - 0.06 13.3 0.3 0.13 12.2 0.3 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 KXT02396.1 - 0.62 9.7 2.3 3.7 7.2 0.9 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Fungal_trans PF04082.18 KXT02397.1 - 4e-11 42.4 0.4 1.2e-10 40.8 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Remorin_C PF03763.13 KXT02399.1 - 0.22 11.4 12.4 0.033 14.1 6.4 2.7 2 0 0 2 2 2 0 Remorin, C-terminal region Dam PF05869.11 KXT02400.1 - 0.081 12.5 0.0 0.083 12.5 0.0 1.1 1 0 0 1 1 1 0 DNA N-6-adenine-methyltransferase (Dam) BTB PF00651.31 KXT02401.1 - 0.00028 21.1 0.0 0.00069 19.8 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KXT02402.1 - 0.00029 21.0 0.0 0.0008 19.6 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain PHD PF00628.29 KXT02403.1 - 2e-10 40.4 8.3 3.2e-10 39.7 8.3 1.3 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 KXT02403.1 - 0.002 18.0 2.6 0.002 18.0 2.6 1.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 C1_1 PF00130.22 KXT02403.1 - 0.0033 17.3 1.2 0.0033 17.3 1.2 1.7 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.6 KXT02403.1 - 0.0052 16.4 2.7 0.015 14.9 2.7 1.8 1 1 0 1 1 1 1 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.6 KXT02403.1 - 0.0068 15.9 6.3 0.025 14.1 6.3 2.0 1 1 0 1 1 1 1 PHD-finger zf-RRPl_C4 PF17026.5 KXT02403.1 - 0.14 12.3 1.7 0.21 11.7 1.7 1.2 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type Rep_fac-A_C PF08646.10 KXT02403.1 - 1.1 9.0 3.0 2.1 8.1 3.0 1.4 1 0 0 1 1 1 0 Replication factor-A C terminal domain DZR PF12773.7 KXT02403.1 - 2.1 8.4 6.1 24 5.1 6.1 2.2 1 1 0 1 1 1 0 Double zinc ribbon Zf_RING PF16744.5 KXT02403.1 - 2.9 8.0 6.1 7.6 6.7 6.1 1.7 1 0 0 1 1 1 0 KIAA1045 RING finger zf-piccolo PF05715.13 KXT02403.1 - 4.6 7.5 6.8 9.4 6.5 6.8 1.5 1 0 0 1 1 1 0 Piccolo Zn-finger zf-RING_2 PF13639.6 KXT02403.1 - 5.2 7.5 6.2 8.3 6.8 6.2 1.3 1 0 0 1 1 1 0 Ring finger domain Glycos_transf_2 PF00535.26 KXT02405.1 - 5.7e-35 120.6 0.0 6.9e-35 120.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KXT02405.1 - 1.7e-12 47.7 0.0 2.5e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KXT02405.1 - 1.3e-05 24.8 0.0 1.8e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KXT02405.1 - 0.00017 21.1 0.0 0.00028 20.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.6 KXT02405.1 - 0.13 12.8 0.0 0.28 11.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 MIP PF00230.20 KXT02406.1 - 3.1e-43 148.1 4.7 5.2e-43 147.4 4.7 1.3 1 0 0 1 1 1 1 Major intrinsic protein Esterase PF00756.20 KXT02407.1 - 5.2e-06 26.3 0.0 0.00075 19.2 0.0 2.3 2 0 0 2 2 2 2 Putative esterase Aldo_ket_red PF00248.21 KXT02408.1 - 5.7e-52 176.7 0.1 1.6e-51 175.2 0.1 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family Z1 PF10593.9 KXT02408.1 - 0.18 11.2 0.0 1.9 8.0 0.0 2.1 2 0 0 2 2 2 0 Z1 domain Kinesin PF00225.23 KXT02409.1 - 5.6e-62 209.6 0.0 8.3e-62 209.0 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXT02409.1 - 2.4e-10 40.6 0.0 1.4e-07 31.5 0.0 3.2 2 1 1 3 3 3 2 Microtubule binding LprI PF07007.12 KXT02409.1 - 0.088 13.5 2.5 0.28 11.9 2.5 1.8 1 0 0 1 1 1 0 Lysozyme inhibitor LprI bZIP_2 PF07716.15 KXT02409.1 - 4.6 7.4 11.3 0.062 13.4 2.9 2.3 2 0 0 2 2 2 0 Basic region leucine zipper Kinesin PF00225.23 KXT02410.1 - 5.6e-62 209.6 0.0 8.3e-62 209.0 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXT02410.1 - 2.4e-10 40.6 0.0 1.4e-07 31.5 0.0 3.2 2 1 1 3 3 3 2 Microtubule binding LprI PF07007.12 KXT02410.1 - 0.088 13.5 2.5 0.28 11.9 2.5 1.8 1 0 0 1 1 1 0 Lysozyme inhibitor LprI bZIP_2 PF07716.15 KXT02410.1 - 4.6 7.4 11.3 0.062 13.4 2.9 2.3 2 0 0 2 2 2 0 Basic region leucine zipper Pkinase PF00069.25 KXT02411.1 - 2.1e-66 224.0 0.0 2.6e-66 223.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT02411.1 - 1.5e-29 103.0 0.0 2.1e-29 102.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KXT02411.1 - 0.011 14.7 0.3 0.016 14.2 0.3 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KXT02411.1 - 0.032 13.0 0.0 0.055 12.3 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 KXT02411.1 - 0.035 13.4 0.0 0.11 11.8 0.0 1.8 2 0 0 2 2 2 0 Kinase-like TB2_DP1_HVA22 PF03134.19 KXT02413.1 - 5.6e-20 71.1 3.5 8.3e-20 70.5 3.5 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Aldolase_II PF00596.21 KXT02414.1 - 6.7e-47 159.8 0.1 8.3e-47 159.5 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Aldolase_II PF00596.21 KXT02415.1 - 8.6e-47 159.5 0.1 1.1e-46 159.2 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Lactamase_B PF00753.27 KXT02416.1 - 2.8e-05 24.2 1.3 5.3e-05 23.3 1.3 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF5513 PF17632.2 KXT02416.1 - 0.038 14.4 0.0 0.098 13.1 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5513) Lactamase_B_2 PF12706.7 KXT02416.1 - 0.082 12.4 0.3 0.19 11.2 0.3 1.7 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Gly-zipper_Omp PF13488.6 KXT02418.1 - 0.0071 16.3 1.1 0.018 15.0 1.1 1.6 1 0 0 1 1 1 1 Glycine zipper Mid2 PF04478.12 KXT02418.1 - 0.038 13.8 0.0 0.069 13.0 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Mucin15 PF15672.5 KXT02418.1 - 2.7 7.4 10.4 1.6 8.2 5.5 2.4 2 1 0 2 2 2 0 Cell-membrane associated Mucin15 SRR1 PF07985.12 KXT02424.1 - 7.2e-05 22.8 0.0 0.00013 21.9 0.0 1.4 1 0 0 1 1 1 1 SRR1 NTP_transf_9 PF04248.12 KXT02426.1 - 5.1e-31 106.4 0.1 6.7e-31 106.0 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF427) BTB PF00651.31 KXT02427.1 - 0.012 15.8 0.0 0.025 14.8 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain zf-PARP PF00645.18 KXT02428.1 - 2.9e-19 69.7 0.1 2.9e-19 69.7 0.1 2.0 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Yip1 PF04893.17 KXT02429.1 - 9.2e-06 25.5 17.2 6.8e-05 22.6 17.2 2.3 1 1 0 1 1 1 1 Yip1 domain RILP PF11461.8 KXT02430.1 - 0.18 12.0 0.9 0.47 10.7 0.9 1.6 1 0 0 1 1 1 0 Rab interacting lysosomal protein DAHP_synth_1 PF00793.20 KXT02432.1 - 3.6e-100 334.4 0.1 4.6e-100 334.0 0.1 1.1 1 0 0 1 1 1 1 DAHP synthetase I family BTB PF00651.31 KXT02433.1 - 0.0072 16.6 0.0 0.057 13.6 0.0 2.1 1 1 1 2 2 2 1 BTB/POZ domain TauD PF02668.16 KXT02434.1 - 4.7e-36 125.0 0.0 6.6e-36 124.5 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KXT02434.1 - 1.3e-10 41.8 0.1 2.6e-10 40.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 KXT02434.1 - 0.0022 17.1 0.1 0.039 13.1 0.0 2.1 2 0 0 2 2 2 1 CsiD TFIIB PF00382.19 KXT02435.1 - 1.5e-37 127.4 0.2 3e-19 68.8 0.0 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 KXT02435.1 - 6.4e-13 48.0 0.4 1.1e-12 47.2 0.4 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding RB_B PF01857.20 KXT02435.1 - 0.0048 16.9 0.0 0.012 15.7 0.0 1.8 1 1 0 1 1 1 1 Retinoblastoma-associated protein B domain Cyclin_C PF02984.19 KXT02435.1 - 0.064 13.4 0.0 5.6 7.1 0.0 2.3 2 0 0 2 2 2 0 Cyclin, C-terminal domain TFIIB PF00382.19 KXT02436.1 - 1.5e-37 127.4 0.2 3e-19 68.8 0.0 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 KXT02436.1 - 6.4e-13 48.0 0.4 1.1e-12 47.2 0.4 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding RB_B PF01857.20 KXT02436.1 - 0.0048 16.9 0.0 0.012 15.7 0.0 1.8 1 1 0 1 1 1 1 Retinoblastoma-associated protein B domain Cyclin_C PF02984.19 KXT02436.1 - 0.064 13.4 0.0 5.6 7.1 0.0 2.3 2 0 0 2 2 2 0 Cyclin, C-terminal domain Alpha-L-AF_C PF06964.12 KXT02437.1 - 1.6e-20 73.9 0.0 6e-20 72.0 0.0 1.8 2 0 0 2 2 2 1 Alpha-L-arabinofuranosidase C-terminal domain Alpha-L-AF_C PF06964.12 KXT02438.1 - 1.6e-20 73.9 0.0 6e-20 72.0 0.0 1.8 2 0 0 2 2 2 1 Alpha-L-arabinofuranosidase C-terminal domain TFIIB PF00382.19 KXT02439.1 - 1.5e-30 105.0 1.3 1.5e-16 60.2 0.1 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 KXT02439.1 - 3.8e-20 72.1 0.1 3.8e-20 72.1 0.1 3.8 4 0 0 4 4 4 1 Brf1-like TBP-binding domain zf-RRN7 PF11781.8 KXT02439.1 - 2.6e-05 23.8 0.5 2.6e-05 23.8 0.5 2.2 3 0 0 3 3 3 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 TF_Zn_Ribbon PF08271.12 KXT02439.1 - 0.00015 21.2 1.2 0.00032 20.2 1.2 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding DUF2318 PF10080.9 KXT02439.1 - 0.0078 16.3 0.3 0.018 15.1 0.3 1.5 1 0 0 1 1 1 1 Predicted membrane protein (DUF2318) Cyclin_N PF00134.23 KXT02439.1 - 0.0088 15.8 0.4 0.29 10.9 0.0 2.5 1 1 1 2 2 2 1 Cyclin, N-terminal domain DUF4428 PF14471.6 KXT02439.1 - 0.25 11.3 0.8 0.73 9.8 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) Aa_trans PF01490.18 KXT02440.1 - 4.7e-21 75.0 29.1 5.8e-21 74.7 29.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 KXT02440.1 - 0.00036 19.5 25.6 0.00036 19.5 25.6 2.3 1 1 1 2 2 2 1 Amino acid permease TB2_DP1_HVA22 PF03134.19 KXT02440.1 - 0.071 13.0 0.8 0.83 9.6 0.2 2.7 2 0 0 2 2 2 0 TB2/DP1, HVA22 family CHZ PF09649.10 KXT02445.1 - 0.0001 21.7 0.5 0.0001 21.7 0.5 1.7 2 0 0 2 2 2 1 Histone chaperone domain CHZ Glyco_hydro_43 PF04616.14 KXT02446.1 - 1.7e-31 109.6 1.0 2.4e-31 109.1 1.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_47 PF01532.20 KXT02448.1 - 3e-134 448.4 0.0 3.4e-134 448.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 GlutR_N PF05201.15 KXT02448.1 - 0.14 11.9 0.1 0.32 10.7 0.1 1.5 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, N-terminal domain TANGO2 PF05742.12 KXT02449.1 - 4.8e-75 252.9 0.0 5.5e-75 252.7 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 DEAD PF00270.29 KXT02450.1 - 4.2e-50 169.9 0.0 3.1e-49 167.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXT02450.1 - 2.6e-14 53.5 0.0 1.1e-13 51.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXT02450.1 - 6.8e-05 22.9 0.0 0.00029 20.9 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KXT02450.1 - 0.0043 17.4 0.0 1.1 9.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KXT02450.1 - 0.013 15.2 0.0 0.06 13.1 0.0 2.1 1 1 1 2 2 2 0 AAA domain DUF5335 PF17269.2 KXT02450.1 - 0.088 12.7 0.2 0.14 12.0 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5335) DUF2313 PF10076.9 KXT02450.1 - 0.13 12.1 0.1 0.23 11.3 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2313) DEAD PF00270.29 KXT02451.1 - 5.5e-50 169.6 0.0 3.7e-49 166.9 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXT02451.1 - 3.1e-14 53.3 0.0 1.3e-13 51.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXT02451.1 - 8.6e-05 22.6 0.0 0.00034 20.6 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KXT02451.1 - 0.0055 17.1 0.0 1.3 9.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KXT02451.1 - 0.017 14.9 0.0 0.062 13.0 0.0 2.0 1 1 1 2 2 2 0 AAA domain DUF5335 PF17269.2 KXT02451.1 - 0.099 12.5 0.2 0.16 11.8 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5335) DUF2313 PF10076.9 KXT02451.1 - 0.15 11.9 0.1 0.27 11.1 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2313) DEAD PF00270.29 KXT02452.1 - 8.1e-50 169.0 0.0 4.9e-49 166.5 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXT02452.1 - 1.3e-24 86.7 0.0 2.6e-23 82.5 0.0 2.7 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXT02452.1 - 0.00011 22.2 0.0 0.00045 20.3 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KXT02452.1 - 0.006 16.9 0.0 1.7 9.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KXT02452.1 - 0.023 14.4 0.0 0.086 12.6 0.0 2.0 1 1 1 2 2 2 0 AAA domain DUF5335 PF17269.2 KXT02452.1 - 0.11 12.3 0.2 0.2 11.5 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5335) DUF2313 PF10076.9 KXT02452.1 - 0.18 11.7 0.1 0.33 10.8 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2313) DEAD PF00270.29 KXT02453.1 - 2.1e-50 170.9 0.0 1.9e-49 167.8 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXT02453.1 - 1.4e-14 54.3 0.0 8.1e-14 51.9 0.0 2.1 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXT02453.1 - 3.6e-05 23.8 0.0 0.00019 21.5 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KXT02453.1 - 0.0021 18.4 0.0 0.66 10.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KXT02453.1 - 0.0067 16.2 0.0 0.033 13.9 0.0 2.2 1 1 1 2 2 2 1 AAA domain DUF5335 PF17269.2 KXT02453.1 - 0.06 13.2 0.2 0.1 12.4 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5335) DUF2313 PF10076.9 KXT02453.1 - 0.09 12.6 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2313) Zn_clus PF00172.18 KXT02454.1 - 0.00011 22.2 7.1 0.00018 21.6 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXT02454.1 - 0.0012 18.0 0.0 0.0028 16.7 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain HOOK PF05622.12 KXT02454.1 - 0.1 10.7 0.5 0.15 10.2 0.5 1.2 1 0 0 1 1 1 0 HOOK protein ABC_tran_CTD PF16326.5 KXT02454.1 - 0.13 12.5 2.0 0.46 10.8 0.1 2.9 3 0 0 3 3 3 0 ABC transporter C-terminal domain PaaX_C PF08223.11 KXT02454.1 - 0.21 11.9 1.2 1.6 9.1 0.1 2.7 3 0 0 3 3 3 0 PaaX-like protein C-terminal domain MreB_Mbl PF06723.13 KXT02455.1 - 0.017 14.0 0.0 0.043 12.6 0.0 1.7 2 0 0 2 2 2 0 MreB/Mbl protein TFR_dimer PF04253.15 KXT02456.1 - 5.4e-34 116.9 0.0 9.7e-34 116.1 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KXT02456.1 - 1.4e-19 70.6 0.0 9e-19 67.9 0.0 2.1 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.22 KXT02456.1 - 2.4e-08 33.9 0.0 5.7e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M9_N PF08453.10 KXT02456.1 - 0.0069 16.1 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M9 N-terminal DUF676 PF05057.14 KXT02458.1 - 2.8e-39 134.9 0.0 4.7e-26 91.7 0.0 3.2 3 0 0 3 3 3 3 Putative serine esterase (DUF676) DUF915 PF06028.11 KXT02458.1 - 0.091 12.1 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) RSN1_7TM PF02714.15 KXT02460.1 - 4.1e-73 246.1 25.0 7.2e-73 245.3 25.0 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KXT02460.1 - 1e-40 139.0 0.6 1e-40 139.0 0.6 2.1 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KXT02460.1 - 3.3e-40 138.2 0.2 5.7e-40 137.4 0.2 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter DUF2683 PF10884.8 KXT02460.1 - 0.095 13.0 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2683) TMF_TATA_bd PF12325.8 KXT02460.1 - 0.15 12.2 1.8 0.33 11.2 0.1 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding TP2 PF01254.18 KXT02460.1 - 3.2 8.4 5.4 6.9 7.3 5.4 1.5 1 0 0 1 1 1 0 Nuclear transition protein 2 ATP_sub_h PF10775.9 KXT02461.1 - 4.4e-27 93.9 1.8 1.3e-26 92.4 2.4 1.5 2 0 0 2 2 2 1 ATP synthase complex subunit h XPG_I_2 PF12813.7 KXT02462.1 - 1e-36 126.7 0.4 3.9e-36 124.8 0.0 2.0 3 0 0 3 3 3 1 XPG domain containing 5_3_exonuc_N PF02739.16 KXT02462.1 - 0.0093 15.9 0.0 0.035 14.0 0.0 1.9 2 0 0 2 2 2 1 5'-3' exonuclease, N-terminal resolvase-like domain F-box-like PF12937.7 KXT02463.1 - 6.7e-05 22.7 1.2 0.00024 21.0 1.2 2.1 1 0 0 1 1 1 1 F-box-like GMC_oxred_N PF00732.19 KXT02464.1 - 7.5e-42 143.7 0.0 9.8e-42 143.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXT02464.1 - 1.2e-30 107.0 0.0 4.8e-30 105.0 0.0 2.1 3 0 0 3 3 3 1 GMC oxidoreductase DUF4407 PF14362.6 KXT02465.1 - 4.8 6.4 11.8 6 6.1 11.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SnoaL PF07366.12 KXT02480.1 - 0.0018 18.1 0.0 0.0028 17.4 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SIR2 PF02146.17 KXT02482.1 - 3e-31 108.7 0.0 3.8e-31 108.4 0.0 1.1 1 0 0 1 1 1 1 Sir2 family CLU PF13236.6 KXT02485.1 - 2.9e-76 256.2 0.0 6.2e-76 255.1 0.0 1.6 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 KXT02485.1 - 4.8e-50 170.0 0.2 3.5e-49 167.2 0.0 2.4 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 KXT02485.1 - 1.3e-40 137.5 24.3 3.6e-11 43.2 0.1 9.1 5 2 4 9 9 9 7 Tetratricopeptide repeat TPR_1 PF00515.28 KXT02485.1 - 1.8e-38 128.8 21.3 1.7e-09 37.1 0.1 9.3 10 0 0 10 10 9 7 Tetratricopeptide repeat Afi1 PF07792.12 KXT02485.1 - 2.4e-38 131.6 0.0 2.4e-38 131.6 0.0 3.9 4 0 0 4 4 2 1 Docking domain of Afi1 for Arf3 in vesicle trafficking TPR_2 PF07719.17 KXT02485.1 - 7.8e-38 125.6 25.3 2.5e-06 27.2 0.0 11.9 11 1 1 12 12 12 7 Tetratricopeptide repeat SPA PF08616.10 KXT02485.1 - 2.9e-33 114.2 0.0 1.3e-32 112.1 0.0 2.1 2 0 0 2 2 2 1 Stabilization of polarity axis DnaJ PF00226.31 KXT02485.1 - 1.7e-27 95.3 3.6 7e-27 93.4 3.6 2.2 1 0 0 1 1 1 1 DnaJ domain TPR_11 PF13414.6 KXT02485.1 - 4.5e-26 90.3 22.1 4.1e-08 32.8 3.0 7.5 6 2 2 8 8 6 5 TPR repeat TPR_10 PF13374.6 KXT02485.1 - 9.5e-26 88.9 23.1 2.6e-05 23.9 0.0 11.1 11 0 0 11 11 11 6 Tetratricopeptide repeat CLU_N PF15044.6 KXT02485.1 - 1.2e-23 83.2 0.1 2.9e-23 82.0 0.1 1.7 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_16 PF13432.6 KXT02485.1 - 3.8e-22 78.7 20.0 3.3e-05 24.4 0.0 6.9 6 1 1 7 7 6 5 Tetratricopeptide repeat TPR_19 PF14559.6 KXT02485.1 - 1.2e-19 70.6 26.4 1.7e-07 31.7 1.3 7.9 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 KXT02485.1 - 4.2e-19 67.1 17.3 0.0038 17.3 0.0 11.1 10 1 1 11 11 10 3 Tetratricopeptide repeat TPR_17 PF13431.6 KXT02485.1 - 2e-17 62.2 15.9 0.0069 16.7 0.2 9.2 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 KXT02485.1 - 2.6e-16 58.9 23.3 0.0022 18.7 0.0 10.2 7 2 3 10 10 9 5 Tetratricopeptide repeat TPR_9 PF13371.6 KXT02485.1 - 1.1e-14 54.3 6.9 0.00014 22.0 0.3 6.6 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 KXT02485.1 - 6.9e-11 41.4 17.1 1.1 9.4 0.1 9.7 11 0 0 11 11 9 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KXT02485.1 - 4.3e-09 36.5 15.2 0.00067 19.8 1.2 6.2 4 2 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KXT02485.1 - 1.4e-06 28.6 27.0 0.35 11.6 0.0 9.1 10 0 0 10 10 8 2 Tetratricopeptide repeat DUF727 PF05303.12 KXT02485.1 - 5.7e-06 26.3 0.0 1.6e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF727) BTAD PF03704.17 KXT02485.1 - 1.2e-05 25.7 14.0 0.53 10.7 0.4 6.8 4 3 2 6 6 6 2 Bacterial transcriptional activator domain Avl9 PF09794.9 KXT02485.1 - 6.6e-05 21.8 0.0 0.81 8.3 0.0 3.6 2 2 1 3 3 3 2 Transport protein Avl9 TPR_4 PF07721.14 KXT02485.1 - 9.6e-05 22.7 13.8 1.9 9.3 0.0 6.6 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KXT02485.1 - 0.00023 20.7 9.8 0.033 13.6 0.1 3.9 3 1 0 3 3 3 1 MalT-like TPR region TPR_15 PF13429.6 KXT02485.1 - 0.0034 16.6 19.6 0.25 10.5 0.4 5.4 5 1 0 5 5 5 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KXT02485.1 - 0.058 13.5 3.7 10 6.3 0.1 4.5 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.6 KXT02485.1 - 0.36 11.2 17.8 3.2 8.1 0.1 6.2 4 2 1 5 5 5 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KXT02485.1 - 0.52 10.8 2.3 43 4.5 0.1 3.9 2 2 2 4 4 4 0 Alkyl sulfatase dimerisation DUF627 PF04781.12 KXT02485.1 - 1.1 9.3 4.8 69 3.5 0.1 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF627) ChAPs PF09295.10 KXT02485.1 - 2.5 7.0 4.3 0.59 9.1 0.2 2.0 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) Ras PF00071.22 KXT02486.1 - 6.9e-59 198.1 0.2 8.1e-59 197.8 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXT02486.1 - 3.7e-36 124.0 0.1 7e-36 123.1 0.1 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXT02486.1 - 4.8e-14 52.2 0.0 6e-14 51.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KXT02486.1 - 1.5e-06 28.2 0.0 2.3e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KXT02486.1 - 2.7e-06 27.0 0.1 4.3e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KXT02486.1 - 8.5e-06 25.3 0.0 1e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KXT02486.1 - 2.4e-05 24.3 1.1 0.16 11.8 0.1 2.4 1 1 2 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 KXT02486.1 - 0.0074 16.7 0.3 0.014 15.8 0.3 1.6 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 KXT02486.1 - 0.087 12.3 0.1 0.16 11.4 0.1 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 KXT02486.1 - 0.12 11.8 0.0 0.33 10.3 0.0 1.8 2 1 0 2 2 2 0 Bacterial TniB protein AAA_22 PF13401.6 KXT02486.1 - 0.15 12.3 0.0 3.4 8.0 0.0 2.2 1 1 1 2 2 2 0 AAA domain BATS PF06968.13 KXT02487.1 - 3e-20 72.2 0.6 7.8e-20 70.8 0.1 2.0 2 1 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 KXT02487.1 - 2.1e-14 54.2 0.1 1.2e-13 51.8 0.1 2.0 2 0 0 2 2 2 1 Radical SAM superfamily Methyltransf_23 PF13489.6 KXT02488.1 - 8.6e-15 54.9 0.0 1.2e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXT02488.1 - 1.4e-10 41.7 0.0 3.1e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXT02488.1 - 6.8e-10 39.5 0.0 2.3e-09 37.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXT02488.1 - 3e-09 36.8 0.0 4.6e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXT02488.1 - 1.1e-08 35.7 0.0 4.5e-08 33.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXT02488.1 - 3e-06 26.8 0.0 8.2e-06 25.3 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family DREV PF05219.12 KXT02488.1 - 0.0075 15.4 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase APH PF01636.23 KXT02489.1 - 2.1e-10 41.0 0.1 3.8e-10 40.1 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXT02489.1 - 0.015 14.9 0.0 0.032 13.8 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Mannosyl_trans PF05007.13 KXT02490.1 - 3e-80 269.8 15.1 4.9e-80 269.1 15.1 1.3 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 KXT02490.1 - 8.5e-13 48.1 3.2 8.5e-13 48.1 3.2 2.1 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U GT87 PF09594.10 KXT02490.1 - 0.00059 19.6 28.0 0.0088 15.8 27.6 2.9 2 1 0 2 2 2 1 Glycosyltransferase family 87 HPD PF05044.12 KXT02490.1 - 0.018 14.9 0.2 0.11 12.4 0.2 1.9 2 0 0 2 2 2 0 Homeo-prospero domain Pkinase PF00069.25 KXT02491.1 - 2e-68 230.6 0.0 3e-68 230.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT02491.1 - 1.1e-46 159.2 0.0 1.7e-46 158.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 KXT02491.1 - 5.3e-26 90.9 0.0 1.2e-25 89.7 0.0 1.6 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.17 KXT02491.1 - 1.4e-16 60.3 0.1 3.9e-16 58.9 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KXT02491.1 - 1.7e-16 60.4 0.1 5.4e-16 58.8 0.1 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.6 KXT02491.1 - 1.4e-07 31.1 0.0 7.7e-05 22.1 0.0 2.3 2 0 0 2 2 2 2 Kinase-like SAM_4 PF18017.1 KXT02491.1 - 5.4e-05 23.1 0.2 0.00013 21.8 0.2 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 KXT02491.1 - 0.00067 20.2 0.0 0.0017 19.0 0.0 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Seadorna_VP7 PF07387.11 KXT02491.1 - 0.0084 15.2 0.1 0.021 13.9 0.1 1.6 2 0 0 2 2 2 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 KXT02491.1 - 0.078 11.7 0.0 0.17 10.6 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase AhpC-TSA PF00578.21 KXT02492.1 - 2.7e-29 101.6 0.0 3.7e-29 101.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KXT02492.1 - 1e-12 48.0 0.0 1.4e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KXT02492.1 - 0.0022 17.8 0.0 0.0052 16.6 0.0 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin PIN_4 PF13638.6 KXT02493.1 - 7e-05 23.1 0.1 0.00016 22.0 0.1 1.6 1 0 0 1 1 1 1 PIN domain Syja_N PF02383.18 KXT02494.1 - 1.7e-92 310.2 0.3 2.8e-92 309.5 0.3 1.3 1 0 0 1 1 1 1 SacI homology domain Glutaredoxin PF00462.24 KXT02495.1 - 1.7e-19 69.7 0.0 2.6e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 KXT02495.1 - 0.0029 18.0 0.1 0.0043 17.4 0.1 1.4 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 KXT02495.1 - 0.004 17.6 0.0 0.0065 16.9 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 KXT02495.1 - 0.0065 16.5 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin domain Sugar_tr PF00083.24 KXT02496.1 - 7.7e-107 358.0 22.8 9.5e-107 357.6 22.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXT02496.1 - 9.2e-24 84.0 32.1 6.9e-17 61.4 12.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 KXT02497.1 - 1.4e-15 57.0 0.0 2.3e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.24 KXT02498.1 - 1.9e-88 297.3 22.1 3.6e-88 296.4 22.1 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXT02498.1 - 4.9e-24 84.9 31.1 2e-15 56.6 16.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MatC_N PF07158.11 KXT02498.1 - 0.027 14.5 4.1 0.035 14.1 2.4 2.1 2 0 0 2 2 2 0 Dicarboxylate carrier protein MatC N-terminus DUF1689 PF07954.11 KXT02498.1 - 0.2 12.0 0.7 0.47 10.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1689) Lig_chan PF00060.26 KXT02498.1 - 0.41 10.5 4.8 1.1 9.1 0.0 2.9 2 1 0 2 2 2 0 Ligand-gated ion channel Sgf11 PF08209.11 KXT02499.1 - 2.8e-11 42.8 0.2 2.8e-11 42.8 0.2 1.7 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.6 KXT02499.1 - 0.04 13.8 1.6 0.12 12.3 1.6 1.8 1 0 0 1 1 1 0 zinc-finger of a C2HC-type DUF3295 PF11702.8 KXT02500.1 - 1.6e-156 522.6 35.9 2e-156 522.2 35.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.10 KXT02500.1 - 5.9e-11 42.0 4.2 1.2e-10 41.1 4.2 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DUF3074 PF11274.8 KXT02501.1 - 1.1e-50 172.1 2.3 1.9e-50 171.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3074) zinc_ribbon_16 PF17034.5 KXT02501.1 - 0.0001 22.5 0.2 0.00026 21.2 0.2 1.7 1 0 0 1 1 1 1 Zinc-ribbon like family Exonuc_VII_L PF02601.15 KXT02501.1 - 2.4 7.6 12.6 3.9 6.9 12.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4407 PF14362.6 KXT02501.1 - 4.9 6.4 18.1 8.7 5.6 18.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PPTA PF01239.22 KXT02502.1 - 1.2e-37 126.6 25.8 2.1e-09 36.8 0.0 5.8 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat NTP_transferase PF00483.23 KXT02503.1 - 2.2e-32 112.6 0.0 3.8e-32 111.8 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase adh_short PF00106.25 KXT02503.1 - 4.6e-22 78.4 0.6 7.2e-22 77.8 0.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT02503.1 - 3.6e-13 49.6 5.8 8e-13 48.5 5.8 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Hexapep PF00132.24 KXT02503.1 - 1.7e-09 37.0 6.1 7.4e-07 28.6 0.1 3.5 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KXT02503.1 - 4.4e-08 33.6 0.0 2e-07 31.5 0.0 2.2 3 0 0 3 3 3 1 MobA-like NTP transferase domain Epimerase PF01370.21 KXT02503.1 - 3.5e-06 26.7 1.2 2.8e-05 23.7 1.2 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KXT02503.1 - 3.5e-05 23.8 1.6 0.0012 18.8 1.6 2.5 1 1 0 1 1 1 1 KR domain IspD PF01128.19 KXT02503.1 - 0.00063 19.6 0.1 0.14 11.8 0.0 2.4 2 0 0 2 2 2 2 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase DUF2968 PF11180.8 KXT02503.1 - 0.028 14.1 0.1 0.052 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Hexapep_2 PF14602.6 KXT02503.1 - 0.16 11.7 1.4 0.56 10.0 0.1 2.6 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase DUF1690 PF07956.11 KXT02504.1 - 1.3e-35 122.9 15.2 4.9e-35 121.0 15.2 1.9 1 1 0 1 1 1 1 Protein of Unknown function (DUF1690) Rootletin PF15035.6 KXT02504.1 - 0.021 14.9 3.8 0.021 14.9 3.8 1.9 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion ProSAAS PF07259.12 KXT02504.1 - 0.1 12.5 0.7 0.18 11.8 0.7 1.4 1 0 0 1 1 1 0 ProSAAS precursor DUF1664 PF07889.12 KXT02504.1 - 0.62 10.1 3.5 0.55 10.3 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF1857 PF08982.11 KXT02505.1 - 3.7e-55 185.8 0.0 4.1e-55 185.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) Alpha-L-AF_C PF06964.12 KXT02506.1 - 2.2e-30 106.0 0.7 3.5e-30 105.4 0.7 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Glyco_hydro_44 PF12891.7 KXT02506.1 - 0.027 14.4 0.1 0.056 13.4 0.1 1.5 1 0 0 1 1 1 0 Glycoside hydrolase family 44 zf-C2HC5 PF06221.13 KXT02507.1 - 4.7e-23 80.9 6.1 7.8e-23 80.2 6.1 1.4 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Zn_clus PF00172.18 KXT02508.1 - 9.2e-08 32.1 6.7 1.4e-07 31.5 6.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KXT02509.1 - 7.3e-08 32.4 6.7 1.1e-07 31.8 6.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain E1-E2_ATPase PF00122.20 KXT02510.1 - 1.5e-37 128.9 10.8 4.6e-29 101.2 0.1 4.2 4 0 0 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KXT02510.1 - 2.3e-26 92.6 7.2 2.3e-26 92.6 7.2 2.8 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KXT02510.1 - 2.9e-21 76.7 0.0 1.8e-19 70.9 0.0 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXT02510.1 - 4.2e-17 62.0 0.0 8.5e-17 61.0 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KXT02510.1 - 1.3e-16 60.0 1.1 2.4e-16 59.2 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KXT02510.1 - 0.0001 22.1 2.7 0.00021 21.1 0.3 2.5 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Pribosyl_synth PF14572.6 KXT02511.1 - 2.2e-44 151.7 1.4 5.3e-39 134.2 1.1 2.5 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 KXT02511.1 - 1.3e-43 147.6 0.4 2.5e-42 143.5 0.1 2.5 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 KXT02511.1 - 3e-17 62.6 0.9 2.7e-16 59.5 0.5 2.2 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KXT02511.1 - 0.00021 20.8 0.2 0.00034 20.1 0.2 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase C9orf72-like PF15019.6 KXT02511.1 - 0.073 12.6 0.9 0.27 10.7 0.1 1.9 2 0 0 2 2 2 0 C9orf72-like protein family Ribosomal_S6e PF01092.19 KXT02512.1 - 1.1e-58 196.6 0.6 2.2e-58 195.6 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S6e DUF2461 PF09365.10 KXT02513.1 - 1.5e-52 178.6 5.1 6.8e-38 130.7 0.0 3.3 3 0 0 3 3 3 3 Conserved hypothetical protein (DUF2461) SDA1 PF05285.12 KXT02513.1 - 4.1 6.7 15.7 1.9 7.8 9.6 2.2 2 0 0 2 2 2 0 SDA1 Abhydrolase_6 PF12697.7 KXT02514.1 - 0.00022 21.9 0.2 0.00049 20.8 0.2 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXT02514.1 - 0.0042 16.4 0.0 0.0084 15.4 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 KXT02514.1 - 0.018 14.8 0.1 0.046 13.4 0.0 1.7 1 1 1 2 2 2 0 PGAP1-like protein Abhydrolase_1 PF00561.20 KXT02514.1 - 0.035 13.7 0.0 0.076 12.6 0.0 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold Cu-oxidase_3 PF07732.15 KXT02515.1 - 5.8e-40 136.0 1.7 5.8e-40 136.0 1.7 2.8 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KXT02515.1 - 1.8e-36 124.9 2.9 3.9e-33 114.1 0.0 2.9 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KXT02515.1 - 2.6e-29 102.4 0.0 1.1e-28 100.4 0.0 2.1 2 0 0 2 2 2 1 Multicopper oxidase Sulfotransfer_4 PF17784.1 KXT02516.1 - 1.7e-27 96.7 0.0 1.7e-24 86.9 0.0 2.2 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KXT02516.1 - 0.00072 20.0 0.6 0.41 11.0 0.1 2.2 1 1 1 2 2 2 2 Sulfotransferase family DUF5044 PF16447.5 KXT02516.1 - 0.073 12.9 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5044) AAA_18 PF13238.6 KXT02516.1 - 0.11 13.1 0.0 0.19 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2985 PF11204.8 KXT02519.1 - 2.6e-40 136.4 1.4 2.6e-40 136.4 1.4 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) DUF3915 PF13054.6 KXT02520.1 - 0.94 9.5 13.9 2 8.4 13.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) DUF1769 PF08588.10 KXT02521.1 - 5.4e-28 97.0 0.5 9.9e-28 96.1 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Cas9_b_hairpin PF17893.1 KXT02521.1 - 0.075 12.8 0.1 0.22 11.3 0.0 1.8 2 0 0 2 2 2 0 CRISPR-associated endonuclease Cas9 beta-hairpin domain Iso_dh PF00180.20 KXT02522.1 - 1e-97 327.5 0.0 1.3e-97 327.1 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase TetR_C_31 PF17940.1 KXT02522.1 - 0.085 13.1 0.0 14 5.9 0.0 2.5 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain FGGY_C PF02782.16 KXT02523.1 - 8e-28 97.5 0.0 1.2e-27 96.9 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KXT02523.1 - 3.1e-16 59.7 0.0 1.4e-11 44.4 0.0 2.5 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Efg1 PF10153.9 KXT02524.1 - 1.1e-33 116.0 8.1 1.1e-33 116.0 8.1 1.9 2 0 0 2 2 2 1 rRNA-processing protein Efg1 GARP PF16731.5 KXT02524.1 - 0.0017 18.1 6.1 0.003 17.3 6.1 1.4 1 0 0 1 1 1 1 Glutamic acid/alanine-rich protein of Trypanosoma DUF4349 PF14257.6 KXT02524.1 - 0.073 12.5 3.9 4.5 6.7 1.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) TMF_TATA_bd PF12325.8 KXT02524.1 - 0.24 11.6 10.8 1.2 9.4 10.8 2.0 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF1525 PF07511.11 KXT02524.1 - 0.67 10.1 3.5 6.1 7.0 3.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1525) PTS_IIA PF02255.16 KXT02524.1 - 0.81 9.8 3.7 1.6 8.8 2.8 2.0 1 1 1 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit CHD5 PF04420.14 KXT02524.1 - 6.6 6.6 5.7 11 5.9 5.7 1.3 1 0 0 1 1 1 0 CHD5-like protein Spore_III_AF PF09581.10 KXT02524.1 - 9.4 6.2 7.7 5.4 7.0 5.5 1.7 1 1 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) RabGAP-TBC PF00566.18 KXT02525.1 - 1.2e-31 110.0 0.3 1.7e-31 109.5 0.3 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain WD40 PF00400.32 KXT02526.1 - 1.2e-06 29.1 3.7 0.0061 17.4 0.0 4.9 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXT02526.1 - 2.5e-05 24.5 0.0 2.7 8.4 0.0 3.5 3 0 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain 4HBT PF03061.22 KXT02527.1 - 3.6e-05 24.0 0.0 5.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 KXT02527.1 - 0.00031 21.2 0.0 0.00042 20.8 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 KXT02527.1 - 0.00037 19.9 0.5 0.00055 19.3 0.5 1.2 1 0 0 1 1 1 1 Acyl-ACP thioesterase Acetyltransf_1 PF00583.25 KXT02528.1 - 4.4e-09 36.6 0.0 5.9e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXT02528.1 - 0.00019 21.8 0.0 0.00031 21.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXT02528.1 - 0.00026 21.0 0.0 0.00045 20.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KXT02528.1 - 0.23 11.6 0.0 0.44 10.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain EF-hand_6 PF13405.6 KXT02529.1 - 6.9e-09 34.9 0.0 0.00014 21.5 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KXT02529.1 - 4.7e-07 30.2 0.1 0.0001 22.7 0.0 1.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KXT02529.1 - 3.6e-06 26.1 0.0 0.021 14.3 0.0 2.3 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 KXT02529.1 - 6.4e-06 26.4 0.0 0.088 13.2 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KXT02529.1 - 0.0026 17.2 0.1 0.027 14.0 0.2 2.2 2 0 0 2 2 2 1 EF hand Zn_clus PF00172.18 KXT02530.1 - 6.5e-09 35.8 8.8 1.5e-08 34.6 8.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Phosphoesterase PF04185.14 KXT02531.1 - 2.2e-36 125.8 2.6 8.1e-36 123.9 2.6 1.9 1 1 0 1 1 1 1 Phosphoesterase family Phosphoesterase PF04185.14 KXT02532.1 - 2.2e-36 125.8 2.6 8.1e-36 123.9 2.6 1.9 1 1 0 1 1 1 1 Phosphoesterase family Phosphoesterase PF04185.14 KXT02533.1 - 2.2e-36 125.8 2.6 8.1e-36 123.9 2.6 1.9 1 1 0 1 1 1 1 Phosphoesterase family Steroid_dh PF02544.16 KXT02534.1 - 0.0048 16.9 1.5 0.12 12.4 0.2 2.2 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase MARVEL PF01284.23 KXT02534.1 - 0.038 14.0 18.1 0.053 13.5 18.1 1.2 1 0 0 1 1 1 0 Membrane-associating domain ERG4_ERG24 PF01222.17 KXT02534.1 - 0.11 11.2 4.5 0.082 11.6 1.9 1.8 1 1 1 2 2 2 0 Ergosterol biosynthesis ERG4/ERG24 family PDR_CDR PF06422.12 KXT02534.1 - 0.3 11.0 1.8 0.82 9.6 0.1 2.1 2 0 0 2 2 2 0 CDR ABC transporter NKAIN PF05640.14 KXT02534.1 - 0.5 9.6 7.5 16 4.7 4.7 2.7 1 1 1 3 3 3 0 Na,K-Atpase Interacting protein LrgB PF04172.16 KXT02534.1 - 1.1 8.7 9.0 0.19 11.3 3.1 1.9 1 1 0 2 2 2 0 LrgB-like family Tetraspanin PF00335.20 KXT02534.1 - 2.3 7.9 8.8 0.2 11.4 0.4 2.1 1 1 0 2 2 2 0 Tetraspanin family DUF3391 PF11871.8 KXT02535.1 - 0.018 15.6 1.1 0.028 15.0 0.0 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3391) zf-BED PF02892.15 KXT02535.1 - 0.028 14.5 2.1 0.059 13.4 2.1 1.6 1 0 0 1 1 1 0 BED zinc finger zf-H2C2_2 PF13465.6 KXT02535.1 - 0.055 13.9 1.6 2.7 8.6 0.3 2.5 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2 PF00096.26 KXT02535.1 - 0.071 13.6 3.8 0.22 12.0 3.8 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXT02535.1 - 0.76 10.8 4.4 2.6 9.1 4.4 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger Cupin_7 PF12973.7 KXT02544.1 - 0.012 15.6 0.0 0.024 14.6 0.0 1.5 1 1 0 1 1 1 0 ChrR Cupin-like domain EHN PF06441.12 KXT02545.1 - 9.1e-30 103.2 0.3 5.3e-28 97.5 0.0 2.3 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KXT02545.1 - 3.8e-13 49.7 0.0 6.5e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXT02545.1 - 0.00026 21.7 0.7 0.00044 20.9 0.7 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family GCV_T PF01571.21 KXT02546.1 - 2.2e-81 273.0 0.0 2.8e-81 272.7 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 KXT02546.1 - 7.7e-22 77.0 0.2 1.4e-21 76.2 0.2 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain TrmE_N PF10396.9 KXT02546.1 - 0.015 15.6 0.0 0.81 10.0 0.0 3.3 4 0 0 4 4 4 0 GTP-binding protein TrmE N-terminus LSM PF01423.22 KXT02548.1 - 8.9e-18 63.7 0.3 1.5e-17 63.0 0.3 1.4 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KXT02548.1 - 0.046 13.4 0.0 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 Hfq protein DUF3818 PF12825.7 KXT02550.1 - 2e-129 431.5 5.0 3.6e-129 430.6 5.0 1.4 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 KXT02550.1 - 3.4e-38 130.6 1.1 3.4e-38 130.6 1.1 2.1 2 0 0 2 2 2 1 PX-associated PX PF00787.24 KXT02550.1 - 8.9e-12 45.0 0.1 9.8e-11 41.6 0.1 2.8 1 1 0 1 1 1 1 PX domain CPSase_L_D2 PF02786.17 KXT02551.1 - 0.031 13.8 0.0 0.057 12.9 0.0 1.4 1 1 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain Sds3 PF08598.11 KXT02552.1 - 6.3e-10 39.4 8.6 6.3e-10 39.4 8.6 1.9 1 1 1 2 2 2 1 Sds3-like Porph_ging PF09697.10 KXT02552.1 - 0.21 12.2 2.4 0.39 11.3 0.1 2.7 1 1 0 2 2 2 0 Protein of unknown function (Porph_ging) RabGAP-TBC PF00566.18 KXT02554.1 - 4.6e-47 160.5 0.0 6.5e-46 156.7 0.0 2.3 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Cnn_1N PF07989.11 KXT02554.1 - 0.0013 18.8 22.7 0.0031 17.6 5.7 3.6 3 1 1 4 4 4 2 Centrosomin N-terminal motif 1 HALZ PF02183.18 KXT02554.1 - 1.1 9.6 15.9 0.18 12.1 0.5 4.1 4 0 0 4 4 4 0 Homeobox associated leucine zipper DivIC PF04977.15 KXT02554.1 - 6.1 6.7 23.4 9.1 6.1 3.3 4.0 1 1 2 3 3 3 0 Septum formation initiator YabA PF06156.13 KXT02554.1 - 8.4 7.1 21.7 3.5 8.3 8.2 3.4 1 1 2 3 3 3 0 Initiation control protein YabA TolA_bind_tri PF16331.5 KXT02554.1 - 9.2 6.4 17.7 3.5 7.8 4.7 3.1 1 1 1 2 2 2 0 TolA binding protein trimerisation bZIP_1 PF00170.21 KXT02554.1 - 9.9 6.4 18.9 3.1 8.0 3.2 3.8 3 0 0 3 3 3 0 bZIP transcription factor Pyridoxal_deC PF00282.19 KXT02555.1 - 6.5e-18 64.6 0.0 1e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KXT02555.1 - 0.00077 18.5 0.0 0.0015 17.6 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KXT02555.1 - 0.0099 15.2 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DUF1775 PF07987.11 KXT02555.1 - 0.014 15.7 0.0 0.024 14.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unkown function (DUF1775) Pkinase PF00069.25 KXT02561.1 - 4.5e-43 147.5 0.0 1.4e-42 145.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT02561.1 - 8.2e-28 97.4 0.0 1.2e-27 96.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXT02561.1 - 3e-05 23.5 0.0 4.6e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KXT02561.1 - 0.062 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PXA PF02194.15 KXT02562.1 - 2e-47 161.5 0.0 2e-47 161.5 0.0 2.8 5 0 0 5 5 5 1 PXA domain Nexin_C PF08628.12 KXT02562.1 - 8.5e-26 90.7 0.0 9.2e-25 87.4 0.0 2.8 3 0 0 3 3 3 1 Sorting nexin C terminal PX PF00787.24 KXT02562.1 - 2.5e-22 79.0 0.5 7.8e-22 77.4 0.3 2.0 2 0 0 2 2 2 1 PX domain RGS PF00615.19 KXT02562.1 - 2.9e-11 43.6 0.0 8.5e-11 42.2 0.0 1.9 1 0 0 1 1 1 1 Regulator of G protein signaling domain PXA PF02194.15 KXT02563.1 - 2e-47 161.5 0.0 2e-47 161.5 0.0 2.8 5 0 0 5 5 5 1 PXA domain Nexin_C PF08628.12 KXT02563.1 - 8.5e-26 90.7 0.0 9.2e-25 87.4 0.0 2.8 3 0 0 3 3 3 1 Sorting nexin C terminal PX PF00787.24 KXT02563.1 - 2.5e-22 79.0 0.5 7.8e-22 77.4 0.3 2.0 2 0 0 2 2 2 1 PX domain RGS PF00615.19 KXT02563.1 - 2.9e-11 43.6 0.0 8.5e-11 42.2 0.0 1.9 1 0 0 1 1 1 1 Regulator of G protein signaling domain Fungal_trans_2 PF11951.8 KXT02564.1 - 1e-08 34.5 1.3 1.5e-08 33.9 1.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT02564.1 - 0.0004 20.4 3.6 0.0004 20.4 3.6 2.3 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribul_P_3_epim PF00834.19 KXT02565.1 - 1.5e-63 213.8 0.0 9.1e-33 113.3 0.0 2.1 1 1 1 2 2 2 2 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.24 KXT02565.1 - 0.0074 15.9 0.1 0.015 14.9 0.0 1.6 2 0 0 2 2 2 1 Orotidine 5'-phosphate decarboxylase / HUMPS family ThiG PF05690.14 KXT02565.1 - 0.011 15.0 0.2 0.015 14.6 0.2 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG QRPTase_C PF01729.19 KXT02565.1 - 0.025 14.4 0.0 0.045 13.5 0.0 1.3 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Metallophos PF00149.28 KXT02566.1 - 7.8e-11 42.9 0.0 1.2e-10 42.3 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXT02566.1 - 4.2e-08 33.5 0.0 2e-05 24.9 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain YabA PF06156.13 KXT02566.1 - 0.19 12.4 0.0 0.34 11.5 0.0 1.4 1 0 0 1 1 1 0 Initiation control protein YabA RTA1 PF04479.13 KXT02567.1 - 8.1e-36 123.6 2.2 2e-31 109.2 0.6 2.4 3 0 0 3 3 3 2 RTA1 like protein Pkinase PF00069.25 KXT02568.1 - 2e-18 66.8 0.0 6.1e-18 65.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT02568.1 - 1.2e-08 34.6 0.0 9.2e-08 31.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase KCNQ2_u3 PF16642.5 KXT02568.1 - 0.29 12.1 9.1 0.21 12.6 2.5 2.8 2 0 0 2 2 2 0 Unstructured region on Potassium channel subunit alpha KvLQT2 DPPIV_N PF00930.21 KXT02569.1 - 1.7e-102 342.8 0.3 2.2e-102 342.4 0.3 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KXT02569.1 - 3.2e-52 177.1 5.5 5.9e-52 176.2 5.5 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KXT02569.1 - 3.9e-06 26.7 4.8 0.00026 20.7 2.6 2.5 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 KXT02569.1 - 6.4e-05 23.7 0.7 0.031 14.9 0.4 2.9 1 1 1 2 2 2 2 Alpha/beta hydrolase family Esterase PF00756.20 KXT02569.1 - 0.0015 18.3 0.1 0.0031 17.2 0.1 1.5 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 KXT02569.1 - 0.016 15.1 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 KXT02569.1 - 0.016 14.8 0.1 0.054 13.1 0.0 1.9 1 1 1 2 2 2 0 alpha/beta hydrolase fold DLH PF01738.18 KXT02569.1 - 0.042 13.4 0.0 0.24 10.9 0.0 2.0 1 1 0 1 1 1 0 Dienelactone hydrolase family F-box PF00646.33 KXT02569.1 - 0.042 13.7 0.7 0.18 11.7 0.1 2.3 2 0 0 2 2 2 0 F-box domain PD40 PF07676.12 KXT02569.1 - 0.048 13.6 1.3 5.6 7.0 0.0 3.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Pectate_lyase_3 PF12708.7 KXT02570.1 - 1.6e-63 214.4 9.4 2e-48 165.1 5.3 2.5 2 0 0 2 2 2 2 Pectate lyase superfamily protein AA_permease_2 PF13520.6 KXT02570.1 - 3.7e-47 161.1 35.2 5.6e-47 160.5 35.2 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXT02570.1 - 1.6e-20 73.2 30.1 2.5e-20 72.6 30.1 1.2 1 0 0 1 1 1 1 Amino acid permease End_N_terminal PF12218.8 KXT02570.1 - 3e-06 26.8 1.7 0.032 13.9 0.0 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase eIF-3_zeta PF05091.12 KXT02571.1 - 1.8e-202 673.9 0.0 2.2e-202 673.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF569 PF04601.13 KXT02571.1 - 0.059 13.1 0.0 0.13 11.9 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF569) Rota_Capsid_VP6 PF00980.17 KXT02572.1 - 0.064 12.2 0.0 0.087 11.7 0.0 1.1 1 0 0 1 1 1 0 Rotavirus major capsid protein VP6 Methyltransf_23 PF13489.6 KXT02573.1 - 1.9e-05 24.5 0.0 2.3e-05 24.3 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase domain Sugar_tr PF00083.24 KXT02574.1 - 2.6e-56 191.4 8.7 2.9e-56 191.2 8.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Sugar_tr PF00083.24 KXT02575.1 - 6.8e-36 124.1 10.9 7.5e-36 124.0 10.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Sugar_tr PF00083.24 KXT02576.1 - 2.6e-56 191.4 8.7 2.9e-56 191.2 8.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Glyco_hydro_3 PF00933.21 KXT02577.1 - 2.5e-45 155.2 0.0 3.6e-45 154.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KXT02577.1 - 5.8e-12 46.0 0.0 1.5e-06 28.3 0.0 2.3 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain Arylsulfotran_2 PF14269.6 KXT02578.1 - 4.8e-29 101.7 0.6 6.9e-29 101.2 0.6 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KXT02578.1 - 6.8e-10 38.4 4.1 8.4e-09 34.8 4.1 2.2 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Ribosomal_60s PF00428.19 KXT02579.1 - 2.3e-26 92.2 9.2 3e-26 91.8 9.2 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF2967 PF11179.8 KXT02579.1 - 0.68 8.0 3.1 0.77 7.8 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) DUF3328 PF11807.8 KXT02580.1 - 7e-31 107.7 0.0 7.8e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) SPT2 PF08243.11 KXT02581.1 - 1.6e-07 31.8 17.0 1.6e-07 31.8 17.0 1.7 2 0 0 2 2 2 1 SPT2 chromatin protein RPN7 PF10602.9 KXT02582.1 - 3.7e-55 186.3 0.3 6.1e-55 185.6 0.3 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 KXT02582.1 - 2.4e-13 50.5 0.0 5.1e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 PCI domain Csc2 PF18320.1 KXT02582.1 - 0.0072 15.3 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Csc2 Crispr TPR_2 PF07719.17 KXT02582.1 - 0.063 13.4 0.2 0.22 11.7 0.2 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXT02582.1 - 0.089 13.7 0.1 0.67 10.9 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat ABC_tran_Xtn PF12848.7 KXT02582.1 - 6.1 6.9 7.3 23 5.1 0.0 3.1 3 0 0 3 3 3 0 ABC transporter Rhomboid PF01694.22 KXT02583.1 - 8.5e-19 68.0 4.3 1.2e-18 67.6 4.3 1.2 1 0 0 1 1 1 1 Rhomboid family adh_short PF00106.25 KXT02585.1 - 8.9e-25 87.3 0.0 1.4e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT02585.1 - 6.7e-22 78.2 0.0 9.7e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase SLAC1 PF03595.17 KXT02586.1 - 0.036 13.3 6.0 0.038 13.2 4.9 1.5 1 1 0 1 1 1 0 Voltage-dependent anion channel DUF4271 PF14093.6 KXT02586.1 - 0.11 12.3 3.5 0.25 11.3 0.4 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4271) SUR7 PF06687.12 KXT02586.1 - 0.18 11.4 3.6 0.072 12.7 0.6 1.8 2 0 0 2 2 2 0 SUR7/PalI family SLAC1 PF03595.17 KXT02587.1 - 0.036 13.3 6.0 0.038 13.2 4.9 1.5 1 1 0 1 1 1 0 Voltage-dependent anion channel DUF4271 PF14093.6 KXT02587.1 - 0.11 12.3 3.5 0.25 11.3 0.4 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4271) SUR7 PF06687.12 KXT02587.1 - 0.18 11.4 3.6 0.072 12.7 0.6 1.8 2 0 0 2 2 2 0 SUR7/PalI family Methyltransf_11 PF08241.12 KXT02588.1 - 2.8e-16 59.9 0.0 6.5e-16 58.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXT02588.1 - 1.3e-15 57.8 0.0 3.5e-15 56.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXT02588.1 - 8.1e-14 51.7 0.0 1.7e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXT02588.1 - 5.8e-12 46.2 0.0 1.5e-11 44.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXT02588.1 - 1.4e-11 44.5 0.0 2.2e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXT02588.1 - 1.1e-07 31.4 0.0 2.8e-07 30.1 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KXT02588.1 - 3.9e-06 26.4 0.0 6.2e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 KXT02588.1 - 1.3e-05 24.9 0.0 2.3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KXT02588.1 - 0.00095 18.7 0.0 0.0018 17.8 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_2 PF00891.18 KXT02588.1 - 0.0011 18.3 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain PCMT PF01135.19 KXT02588.1 - 0.0018 18.1 0.0 0.058 13.1 0.0 2.2 1 1 1 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 KXT02588.1 - 0.0023 17.0 0.0 0.0038 16.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase TehB PF03848.14 KXT02588.1 - 0.0053 16.2 0.0 0.0092 15.4 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB PrmA PF06325.13 KXT02588.1 - 0.0063 15.9 0.0 0.0098 15.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_17 PF12692.7 KXT02588.1 - 0.042 13.8 0.0 0.08 12.9 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase MetW PF07021.12 KXT02588.1 - 0.15 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW RRM_1 PF00076.22 KXT02589.1 - 1.6e-14 53.4 0.1 1.7e-09 37.3 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) S1 PF00575.23 KXT02590.1 - 7.7e-09 35.8 0.5 1.3e-08 35.1 0.1 1.6 2 0 0 2 2 2 1 S1 RNA binding domain SHS2_Rpb7-N PF03876.17 KXT02590.1 - 0.00031 21.1 0.0 0.00052 20.3 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RNA_pol_Rbc25 PF08292.12 KXT02590.1 - 0.0031 17.8 0.0 0.0062 16.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 DRMBL PF07522.14 KXT02591.1 - 5.4e-34 116.7 0.0 1.2e-33 115.6 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 KXT02591.1 - 0.00024 20.7 0.0 0.00045 19.8 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain TIP49 PF06068.13 KXT02591.1 - 0.063 12.5 0.0 0.096 11.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain PMT PF02366.18 KXT02592.1 - 1.4e-84 283.5 17.9 1.4e-84 283.5 17.9 1.6 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KXT02592.1 - 1.4e-69 233.7 7.5 1.4e-69 233.7 7.5 3.2 2 1 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KXT02592.1 - 1.6e-19 70.5 0.9 2.6e-19 69.8 0.9 1.3 1 0 0 1 1 1 1 MIR domain PLA2_B PF01735.18 KXT02593.1 - 2.1e-180 600.3 3.2 2.7e-180 600.0 3.2 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Methyltransf_11 PF08241.12 KXT02594.1 - 4.4e-08 33.7 0.0 1.1e-07 32.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXT02594.1 - 0.00016 21.5 0.0 0.00033 20.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXT02594.1 - 0.0066 17.1 0.0 0.026 15.2 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Caudo_TAP PF02413.17 KXT02594.1 - 0.34 11.1 2.6 2.7 8.1 0.3 2.6 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein, lambda gpK DUF3425 PF11905.8 KXT02595.1 - 4.7e-11 42.7 0.6 8.7e-11 41.9 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Aminotran_4 PF01063.19 KXT02596.1 - 5.2e-28 98.4 0.0 6.9e-28 98.0 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV V-ATPase_C PF03223.15 KXT02597.1 - 2.1e-121 405.8 0.0 2.4e-121 405.6 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C mRNA_cap_C PF03919.15 KXT02597.1 - 0.066 13.8 0.0 0.17 12.5 0.0 1.7 1 0 0 1 1 1 0 mRNA capping enzyme, C-terminal domain POTRA_TamA_1 PF17243.2 KXT02598.1 - 0.062 13.4 0.2 0.062 13.4 0.2 3.1 3 0 0 3 3 3 0 POTRA domain TamA domain 1 POTRA_TamA_1 PF17243.2 KXT02599.1 - 0.061 13.4 0.2 0.061 13.4 0.2 3.1 3 0 0 3 3 3 0 POTRA domain TamA domain 1 DUF5345 PF17280.2 KXT02600.1 - 0.0078 16.2 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5345) CECR6_TMEM121 PF14997.6 KXT02600.1 - 0.012 15.5 1.2 0.013 15.4 0.2 1.5 2 0 0 2 2 2 0 CECR6/TMEM121 family DUF2798 PF11391.8 KXT02600.1 - 0.76 9.9 8.4 0.14 12.2 1.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2798) PNP_UDP_1 PF01048.20 KXT02601.1 - 1.9e-40 138.6 0.0 2.3e-40 138.3 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily DNA_pol_B_palm PF14792.6 KXT02601.1 - 0.17 12.1 0.0 0.28 11.4 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase beta palm PBP PF01161.20 KXT02602.1 - 2.5e-17 63.4 0.3 3.3e-17 63.0 0.3 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein GP52 PF17468.2 KXT02602.1 - 0.14 12.3 0.1 15 5.8 0.0 2.6 2 0 0 2 2 2 0 Phage gene product 52 PBP PF01161.20 KXT02603.1 - 2.5e-17 63.4 0.3 3.3e-17 63.0 0.3 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein GP52 PF17468.2 KXT02603.1 - 0.14 12.3 0.1 15 5.8 0.0 2.6 2 0 0 2 2 2 0 Phage gene product 52 FAD_binding_3 PF01494.19 KXT02604.1 - 2.4e-26 92.8 0.0 3.4e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXT02604.1 - 1.1e-06 28.2 0.7 0.00022 20.6 0.3 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXT02604.1 - 0.00014 21.6 2.7 0.17 11.4 0.9 2.3 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXT02604.1 - 0.00032 20.9 0.5 0.0008 19.6 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KXT02604.1 - 0.00042 19.3 2.2 0.048 12.5 0.7 2.5 1 1 2 3 3 3 2 Tryptophan halogenase Pyr_redox PF00070.27 KXT02604.1 - 0.0012 19.3 0.3 0.17 12.4 0.1 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXT02604.1 - 0.0058 15.4 0.7 0.02 13.6 0.1 2.1 3 0 0 3 3 3 1 HI0933-like protein Amino_oxidase PF01593.24 KXT02604.1 - 0.013 14.8 0.2 0.025 13.9 0.0 1.5 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase GIDA PF01134.22 KXT02604.1 - 0.021 13.9 0.7 0.037 13.1 0.7 1.5 1 1 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KXT02604.1 - 0.045 12.8 1.0 0.086 11.9 0.7 1.6 1 1 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 KXT02604.1 - 0.053 12.8 0.1 0.096 11.9 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Dynamin_M PF01031.20 KXT02605.1 - 6.3e-110 366.9 0.0 1.4e-109 365.7 0.0 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 KXT02605.1 - 1.2e-55 188.1 0.0 1.2e-55 188.1 0.0 2.0 3 0 0 3 3 3 1 Dynamin family GED PF02212.18 KXT02605.1 - 3.4e-31 107.2 1.3 8.3e-31 106.0 1.3 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KXT02605.1 - 0.00044 20.3 0.3 0.0053 16.8 0.3 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dabb PF07876.12 KXT02606.1 - 0.00041 20.9 0.1 0.0006 20.4 0.1 1.2 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Melibiase PF02065.18 KXT02607.1 - 1.1e-38 133.1 0.0 1.6e-38 132.6 0.0 1.2 1 0 0 1 1 1 1 Melibiase Glyco_hydro_36N PF16875.5 KXT02607.1 - 3.8e-05 23.4 0.1 0.00012 21.7 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 36 N-terminal domain Melibiase_2 PF16499.5 KXT02607.1 - 0.039 13.1 0.0 0.069 12.3 0.0 1.3 1 0 0 1 1 1 0 Alpha galactosidase A NPR3 PF03666.13 KXT02608.1 - 4.8e-84 282.8 5.3 1.3e-45 156.1 1.1 2.8 2 1 1 3 3 3 2 Nitrogen Permease regulator of amino acid transport activity 3 PBP1_TM PF14812.6 KXT02608.1 - 0.25 11.7 5.0 0.4 11.1 3.7 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Mce4_CUP1 PF11887.8 KXT02609.1 - 0.026 14.0 0.3 0.045 13.2 0.3 1.4 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative cobW PF02492.19 KXT02610.1 - 4.5e-32 111.1 0.0 5.5e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 KXT02610.1 - 1.5e-05 24.2 0.6 0.00012 21.2 0.6 1.9 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 KXT02610.1 - 0.0014 18.7 0.0 0.0033 17.5 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KXT02610.1 - 0.014 15.8 0.0 0.018 15.4 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 KXT02610.1 - 0.018 15.0 0.0 0.027 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 KXT02610.1 - 0.026 15.0 0.0 0.054 14.0 0.0 1.3 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 KXT02610.1 - 0.094 12.7 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 KXT02610.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Ank PF00023.30 KXT02610.1 - 0.11 12.9 0.2 10 6.8 0.0 3.1 2 0 0 2 2 2 0 Ankyrin repeat CbiA PF01656.23 KXT02610.1 - 0.12 12.4 0.1 0.24 11.5 0.1 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.6 KXT02610.1 - 0.16 12.5 0.0 0.37 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KXT02610.1 - 0.19 11.6 0.0 0.28 11.1 0.0 1.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NACHT PF05729.12 KXT02610.1 - 0.2 11.5 0.0 0.35 10.8 0.0 1.5 1 1 0 1 1 1 0 NACHT domain Parvo_NS1 PF01057.17 KXT02610.1 - 0.21 10.6 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Glyco_hydro_3_C PF01915.22 KXT02631.1 - 9.9e-45 153.0 0.0 1.7e-44 152.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXT02631.1 - 1.7e-35 123.0 0.0 2.8e-35 122.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXT02631.1 - 8.2e-25 86.7 0.2 1.5e-24 85.8 0.2 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3_C PF01915.22 KXT02632.1 - 6.6e-45 153.6 0.0 1.1e-44 152.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXT02632.1 - 1.6e-35 123.0 0.0 2.8e-35 122.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXT02632.1 - 8.1e-25 86.7 0.2 1.5e-24 85.9 0.2 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain CRM1_C PF08767.11 KXT02633.1 - 1.4e-121 405.6 8.9 6.8e-121 403.3 5.3 3.3 2 1 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.12 KXT02633.1 - 1.8e-39 135.2 8.9 7.3e-37 126.7 4.7 4.4 4 0 0 4 4 4 2 Exportin 1-like protein CRM1_repeat_2 PF18784.1 KXT02633.1 - 3.9e-33 112.9 2.7 3.9e-33 112.9 2.7 2.6 3 0 0 3 3 3 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 KXT02633.1 - 6.5e-30 103.0 2.7 1.4e-29 101.9 1.2 2.5 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 KXT02633.1 - 1.4e-19 69.3 2.9 1.4e-19 69.3 2.9 1.8 2 0 0 2 2 2 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 KXT02633.1 - 2.3e-13 49.8 0.1 1.2e-12 47.6 0.1 2.4 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3385 PF11865.8 KXT02633.1 - 0.0018 18.2 0.9 0.2 11.5 0.0 4.1 4 0 0 4 4 4 1 Domain of unknown function (DUF3385) HD_assoc PF13286.6 KXT02633.1 - 0.064 13.8 2.3 24 5.5 0.0 4.3 5 0 0 5 5 5 0 Phosphohydrolase-associated domain Vac14_Fab1_bd PF12755.7 KXT02633.1 - 0.71 10.5 3.8 8.7 7.0 0.0 4.1 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region CRM1_C PF08767.11 KXT02634.1 - 5.1e-131 436.6 5.7 1.2e-130 435.4 2.5 2.7 2 0 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.12 KXT02634.1 - 8.6e-40 136.2 10.1 7e-37 126.8 4.7 4.7 3 1 1 4 4 4 2 Exportin 1-like protein CRM1_repeat_2 PF18784.1 KXT02634.1 - 3.8e-33 112.9 2.7 3.8e-33 112.9 2.7 2.7 3 0 0 3 3 3 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 KXT02634.1 - 6e-30 103.1 2.7 1.4e-29 102.0 1.2 2.5 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 KXT02634.1 - 1.3e-19 69.4 2.9 1.3e-19 69.4 2.9 1.9 2 0 0 2 2 2 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 KXT02634.1 - 2.4e-13 49.8 0.1 1.1e-12 47.6 0.1 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3385 PF11865.8 KXT02634.1 - 0.006 16.5 3.6 0.2 11.6 0.0 4.4 4 1 1 5 5 5 1 Domain of unknown function (DUF3385) HD_assoc PF13286.6 KXT02634.1 - 0.058 13.9 2.3 23 5.6 0.0 4.3 5 0 0 5 5 5 0 Phosphohydrolase-associated domain BID PF06393.11 KXT02634.1 - 0.062 12.8 0.4 0.18 11.3 0.4 1.8 1 0 0 1 1 1 0 BH3 interacting domain (BID) Vac14_Fab1_bd PF12755.7 KXT02634.1 - 0.38 11.4 3.4 8.5 7.0 0.0 4.3 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region WAC_Acf1_DNA_bd PF10537.9 KXT02635.1 - 2e-35 121.3 0.0 7.8e-35 119.4 0.0 2.1 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 KXT02635.1 - 3.9e-23 81.8 0.9 3.9e-23 81.8 0.9 3.2 3 0 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 KXT02635.1 - 8.7e-15 54.8 1.4 1.6e-14 54.0 1.4 1.4 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 KXT02635.1 - 0.029 13.9 0.0 0.078 12.5 0.0 1.7 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 Choline_kinase PF01633.20 KXT02635.1 - 0.072 12.7 0.5 0.18 11.4 0.5 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase Troponin-I_N PF11636.8 KXT02635.1 - 0.13 12.2 0.5 0.32 11.0 0.5 1.6 1 0 0 1 1 1 0 Troponin I residues 1-32 Alpha-2-MRAP_C PF06401.11 KXT02635.1 - 1.8 8.5 14.7 0.1 12.5 1.3 2.7 2 0 0 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain WAC_Acf1_DNA_bd PF10537.9 KXT02636.1 - 1.5e-33 115.3 0.0 5.9e-33 113.4 0.0 2.1 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 KXT02636.1 - 4e-23 81.8 0.9 4e-23 81.8 0.9 3.3 3 0 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 KXT02636.1 - 8.8e-15 54.8 1.4 1.6e-14 54.0 1.4 1.4 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 KXT02636.1 - 0.029 13.9 0.0 0.079 12.5 0.0 1.7 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 Choline_kinase PF01633.20 KXT02636.1 - 0.072 12.7 0.5 0.18 11.4 0.5 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase Troponin-I_N PF11636.8 KXT02636.1 - 0.13 12.2 0.5 0.32 11.0 0.5 1.6 1 0 0 1 1 1 0 Troponin I residues 1-32 Alpha-2-MRAP_C PF06401.11 KXT02636.1 - 1.8 8.5 14.7 0.1 12.5 1.3 2.7 2 0 0 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain Pyr_redox_2 PF07992.14 KXT02637.1 - 3.7e-37 128.2 0.0 2.7e-34 118.8 0.0 1.9 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXT02637.1 - 1.2e-17 64.2 0.1 2.4e-13 50.4 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXT02637.1 - 3.8e-09 36.6 0.0 0.023 14.3 0.0 3.7 3 1 1 4 4 4 3 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXT02637.1 - 9e-09 35.0 0.0 3e-07 30.0 0.0 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KXT02637.1 - 1.7e-06 28.4 0.0 0.0063 16.9 0.0 3.0 3 0 0 3 3 3 2 Putative NAD(P)-binding K_oxygenase PF13434.6 KXT02637.1 - 2.7e-06 26.8 0.0 1.2e-05 24.7 0.0 2.1 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KXT02637.1 - 4e-06 26.9 0.3 2.6 8.0 0.0 4.3 3 1 1 4 4 4 2 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KXT02637.1 - 0.00017 20.6 0.1 3 6.6 0.0 3.1 2 1 1 3 3 3 3 Tryptophan halogenase NAD_binding_8 PF13450.6 KXT02637.1 - 0.0021 18.2 0.0 2.7 8.3 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 KXT02637.1 - 0.023 15.0 0.7 1.4 9.2 0.0 2.7 3 0 0 3 3 3 0 TrkA-N domain HI0933_like PF03486.14 KXT02637.1 - 0.062 12.0 0.0 19 3.8 0.1 3.1 3 1 1 4 4 4 0 HI0933-like protein L27_1 PF09058.10 KXT02637.1 - 0.087 12.8 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 L27_1 TFIID-18kDa PF02269.16 KXT02638.1 - 3.9e-18 65.3 0.0 6.8e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Histone PF00125.24 KXT02638.1 - 0.013 15.8 1.6 0.023 15.1 0.0 2.0 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KXT02638.1 - 0.088 13.2 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 CENP-S protein Pyr_redox_2 PF07992.14 KXT02639.1 - 3.7e-37 128.2 0.0 2.7e-34 118.8 0.0 1.9 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXT02639.1 - 1.2e-17 64.2 0.1 2.4e-13 50.4 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXT02639.1 - 3.8e-09 36.6 0.0 0.023 14.3 0.0 3.7 3 1 1 4 4 4 3 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXT02639.1 - 9e-09 35.0 0.0 3e-07 30.0 0.0 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KXT02639.1 - 1.7e-06 28.4 0.0 0.0063 16.9 0.0 3.0 3 0 0 3 3 3 2 Putative NAD(P)-binding K_oxygenase PF13434.6 KXT02639.1 - 2.7e-06 26.8 0.0 1.2e-05 24.7 0.0 2.1 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KXT02639.1 - 4e-06 26.9 0.3 2.6 8.0 0.0 4.3 3 1 1 4 4 4 2 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KXT02639.1 - 0.00017 20.6 0.1 3 6.6 0.0 3.1 2 1 1 3 3 3 3 Tryptophan halogenase NAD_binding_8 PF13450.6 KXT02639.1 - 0.0021 18.2 0.0 2.7 8.3 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 KXT02639.1 - 0.023 15.0 0.7 1.4 9.2 0.0 2.7 3 0 0 3 3 3 0 TrkA-N domain HI0933_like PF03486.14 KXT02639.1 - 0.062 12.0 0.0 19 3.8 0.1 3.1 3 1 1 4 4 4 0 HI0933-like protein L27_1 PF09058.10 KXT02639.1 - 0.087 12.8 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 L27_1 Alg6_Alg8 PF03155.15 KXT02640.1 - 9.9e-176 585.4 26.9 1.1e-175 585.2 26.9 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family DUF5464 PF17552.2 KXT02640.1 - 0.019 15.2 0.2 0.099 12.9 0.2 2.3 1 0 0 1 1 1 0 Family of unknown function (DUF5464) Oxidored_FMN PF00724.20 KXT02641.1 - 1.4e-19 70.6 0.0 2.9e-19 69.5 0.0 1.6 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Septin PF00735.18 KXT02642.1 - 2.1e-113 378.3 0.3 2.6e-113 378.0 0.3 1.1 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KXT02642.1 - 4e-08 33.3 0.0 1.5e-07 31.5 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXT02642.1 - 2.1e-05 24.5 0.5 0.00026 20.9 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 KXT02642.1 - 2.5e-05 23.7 0.0 4.9e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 KXT02642.1 - 2.6e-05 23.9 0.1 0.047 13.2 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KXT02642.1 - 0.0014 18.7 0.3 1.8 8.6 0.1 2.6 1 1 1 2 2 2 2 Dynamin family NB-ARC PF00931.22 KXT02642.1 - 0.0021 17.3 0.0 0.0032 16.7 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KXT02642.1 - 0.0039 17.6 0.0 0.0072 16.7 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXT02642.1 - 0.01 16.1 0.0 0.035 14.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KXT02642.1 - 0.012 15.1 0.3 0.089 12.3 0.1 2.4 2 1 0 2 2 2 0 P-loop containing dynein motor region Gtr1_RagA PF04670.12 KXT02642.1 - 0.024 14.0 0.0 1 8.7 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.18 KXT02642.1 - 0.025 13.9 0.0 0.046 13.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family FOXO_KIX_bdg PF16675.5 KXT02642.1 - 0.03 14.6 1.7 3.9 7.9 0.6 2.6 2 0 0 2 2 2 0 KIX-binding domain of forkhead box O, CR2 T2SSE PF00437.20 KXT02642.1 - 0.037 13.1 0.1 0.078 12.0 0.1 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 KXT02642.1 - 0.037 14.5 0.7 0.075 13.5 0.2 1.8 1 1 0 1 1 1 0 ABC transporter Zn_clus PF00172.18 KXT02643.1 - 0.0071 16.4 7.9 0.016 15.3 7.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DASH_Dad2 PF08654.10 KXT02644.1 - 6.2e-32 110.0 1.4 6.2e-32 110.0 1.4 1.4 2 0 0 2 2 2 1 DASH complex subunit Dad2 DASH_Duo1 PF08651.10 KXT02644.1 - 0.021 14.6 0.1 0.04 13.7 0.1 1.4 1 0 0 1 1 1 0 DASH complex subunit Duo1 CH_2 PF06294.11 KXT02644.1 - 0.07 13.3 0.0 0.12 12.5 0.0 1.5 1 1 0 1 1 1 0 CH-like domain in sperm protein GvpL_GvpF PF06386.11 KXT02644.1 - 0.14 12.1 3.0 0.15 11.9 3.0 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Seryl_tRNA_N PF02403.22 KXT02644.1 - 1.2 9.4 7.9 0.28 11.4 1.7 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Striatin PF08232.12 KXT02645.1 - 0.013 16.1 1.0 0.013 16.1 1.0 1.7 2 0 0 2 2 2 0 Striatin family TPR_MLP1_2 PF07926.12 KXT02645.1 - 0.14 12.2 0.8 0.26 11.4 0.8 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF3253 PF11625.8 KXT02646.1 - 4.2e-19 68.6 0.0 7.7e-19 67.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3253) NUDIX PF00293.28 KXT02647.1 - 7.8e-17 61.6 0.5 3.8e-16 59.3 0.1 2.0 1 1 1 2 2 2 1 NUDIX domain Methyltransf_23 PF13489.6 KXT02648.1 - 2.6e-24 85.9 0.0 4.4e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXT02648.1 - 1.7e-12 47.9 0.0 4.2e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXT02648.1 - 6.9e-11 42.6 0.0 1.8e-10 41.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXT02648.1 - 2.3e-09 37.2 0.0 3.7e-08 33.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXT02648.1 - 9e-08 32.8 0.0 6.4e-07 30.0 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXT02648.1 - 0.013 14.9 0.0 0.053 12.8 0.0 1.9 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KXT02648.1 - 0.013 14.9 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase FtsJ PF01728.19 KXT02648.1 - 0.025 14.7 0.0 0.046 13.8 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.14 KXT02648.1 - 0.038 13.5 0.0 0.076 12.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.18 KXT02648.1 - 0.045 13.1 0.0 0.07 12.4 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain CMAS PF02353.20 KXT02648.1 - 0.081 12.2 0.0 0.15 11.3 0.0 1.5 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase GidB PF02527.15 KXT02648.1 - 0.12 11.7 0.0 0.63 9.3 0.0 2.0 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_23 PF13489.6 KXT02649.1 - 2.8e-24 85.8 0.0 4.8e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXT02649.1 - 1.8e-12 47.8 0.0 4.4e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXT02649.1 - 7.4e-11 42.6 0.0 1.9e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXT02649.1 - 2.7e-09 37.0 0.0 3.9e-08 33.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXT02649.1 - 9.8e-08 32.7 0.0 6.7e-07 30.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXT02649.1 - 0.014 14.7 0.0 0.054 12.8 0.0 1.8 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KXT02649.1 - 0.014 14.8 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.14 KXT02649.1 - 0.04 13.5 0.0 0.079 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain CMAS PF02353.20 KXT02649.1 - 0.093 12.0 0.0 0.18 11.0 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 KXT02649.1 - 0.1 11.9 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain GidB PF02527.15 KXT02649.1 - 0.13 11.6 0.0 0.66 9.3 0.0 1.9 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_23 PF13489.6 KXT02650.1 - 2.7e-24 85.9 0.0 4.8e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXT02650.1 - 1.7e-12 47.8 0.0 4.4e-12 46.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXT02650.1 - 7.3e-11 42.6 0.0 1.9e-10 41.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXT02650.1 - 2.6e-09 37.1 0.0 4e-08 33.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXT02650.1 - 9.6e-08 32.7 0.0 6.8e-07 30.0 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KXT02650.1 - 0.014 14.9 0.0 0.028 13.9 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.18 KXT02650.1 - 0.014 14.7 0.0 0.054 12.8 0.0 1.9 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family MTS PF05175.14 KXT02650.1 - 0.039 13.5 0.0 0.08 12.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.18 KXT02650.1 - 0.047 13.0 0.0 0.074 12.3 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain CMAS PF02353.20 KXT02650.1 - 0.086 12.1 0.0 0.17 11.2 0.0 1.5 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase GidB PF02527.15 KXT02650.1 - 0.12 11.6 0.0 0.67 9.3 0.0 2.0 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_23 PF13489.6 KXT02651.1 - 2.6e-24 85.9 0.0 4.4e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXT02651.1 - 1.7e-12 47.9 0.0 4.2e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXT02651.1 - 6.9e-11 42.6 0.0 1.8e-10 41.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXT02651.1 - 2.3e-09 37.2 0.0 3.7e-08 33.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXT02651.1 - 9e-08 32.8 0.0 6.4e-07 30.0 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXT02651.1 - 0.013 14.9 0.0 0.053 12.8 0.0 1.9 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KXT02651.1 - 0.013 14.9 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase FtsJ PF01728.19 KXT02651.1 - 0.025 14.7 0.0 0.046 13.8 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.14 KXT02651.1 - 0.038 13.5 0.0 0.076 12.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.18 KXT02651.1 - 0.045 13.1 0.0 0.07 12.4 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain CMAS PF02353.20 KXT02651.1 - 0.081 12.2 0.0 0.15 11.3 0.0 1.5 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase GidB PF02527.15 KXT02651.1 - 0.12 11.7 0.0 0.63 9.3 0.0 2.0 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G mRNA_cap_enzyme PF01331.19 KXT02652.1 - 1.6e-49 168.4 1.3 1.9e-49 168.1 0.0 1.7 2 0 0 2 2 2 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 KXT02652.1 - 3.3e-27 95.3 1.2 5.8e-27 94.5 0.0 1.9 2 0 0 2 2 2 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 KXT02652.1 - 1.2e-08 34.9 0.4 0.0007 19.3 0.0 2.7 2 1 1 3 3 3 2 ATP dependent DNA ligase domain DUF3634 PF12321.8 KXT02652.1 - 0.035 14.5 0.3 0.21 12.0 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3634) DUF4407 PF14362.6 KXT02652.1 - 1.1 8.6 9.7 1.6 8.0 9.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Coilin_N PF15862.5 KXT02652.1 - 5.4 6.8 10.0 9.5 6.0 10.0 1.3 1 0 0 1 1 1 0 Coilin N-terminus CCDC53 PF10152.9 KXT02652.1 - 5.7 7.3 8.9 9.8 6.6 8.9 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DND1_DSRM PF14709.7 KXT02653.1 - 0.019 15.2 0.4 0.036 14.3 0.1 1.7 2 0 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.26 KXT02653.1 - 0.029 15.1 0.0 0.068 13.9 0.0 1.5 1 0 0 1 1 1 0 Double-stranded RNA binding motif PhyH PF05721.13 KXT02654.1 - 1.5e-08 35.2 1.2 9.4e-08 32.6 0.2 2.3 2 1 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 KXT02654.1 - 1.5e-05 24.0 0.4 0.028 13.2 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1479) Kelch_2 PF07646.15 KXT02654.1 - 0.37 10.9 3.3 1.3 9.1 1.1 2.4 2 0 0 2 2 2 0 Kelch motif BRAP2 PF07576.12 KXT02655.1 - 2e-31 108.2 0.0 4e-31 107.2 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 KXT02655.1 - 4.8e-20 71.6 6.9 1.8e-19 69.8 6.9 1.9 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 KXT02655.1 - 2.9e-08 33.9 8.8 2.9e-08 33.9 8.8 1.9 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXT02655.1 - 2.6e-06 27.1 8.2 6.3e-06 25.9 8.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXT02655.1 - 2.3e-05 24.2 7.3 6.2e-05 22.8 7.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXT02655.1 - 0.00011 22.2 4.5 0.00074 19.5 4.8 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 KXT02655.1 - 0.00012 21.8 4.9 0.00037 20.2 4.9 2.0 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 KXT02655.1 - 0.00016 21.9 6.0 0.00053 20.2 6.0 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 KXT02655.1 - 0.0019 18.1 3.2 0.0053 16.6 3.2 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.6 KXT02655.1 - 0.0024 17.7 7.1 0.0024 17.7 7.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXT02655.1 - 0.0026 17.7 6.5 0.0026 17.7 6.5 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KXT02655.1 - 0.025 14.6 5.6 0.078 13.0 5.6 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Hrs_helical PF12210.8 KXT02655.1 - 0.2 12.2 16.0 0.67 10.5 5.4 2.6 1 1 1 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate GARP PF16731.5 KXT02655.1 - 0.66 9.6 31.5 0.014 15.1 22.5 2.3 2 1 1 3 3 2 0 Glutamic acid/alanine-rich protein of Trypanosoma DHR10 PF18595.1 KXT02655.1 - 1.1 9.4 29.4 1.5 8.9 14.1 2.8 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain Exonuc_VII_L PF02601.15 KXT02655.1 - 1.3 8.5 16.4 2.2 7.8 16.4 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit YkyA PF10368.9 KXT02655.1 - 2 8.1 29.3 3.3 7.4 29.3 1.3 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein Methyltrn_RNA_4 PF09936.9 KXT02655.1 - 2.7 7.8 4.8 4.9 7.0 4.8 1.3 1 0 0 1 1 1 0 SAM-dependent RNA methyltransferase Prok-RING_4 PF14447.6 KXT02655.1 - 3.3 7.7 19.3 0.41 10.5 9.3 3.2 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 PHM7_cyt PF14703.6 KXT02655.1 - 5.2 7.3 14.9 1.2 9.3 9.3 2.3 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Zn_ribbon_17 PF17120.5 KXT02655.1 - 6.5 6.5 13.6 0.068 12.8 5.0 2.1 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type AAA_23 PF13476.6 KXT02655.1 - 6.9 7.1 16.0 14 6.1 16.0 1.5 1 0 0 1 1 1 0 AAA domain p450 PF00067.22 KXT02656.1 - 1.2e-35 123.1 0.0 1.9e-35 122.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.32 KXT02657.1 - 6.6e-53 175.5 17.3 1.1e-10 41.9 1.5 9.0 7 3 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXT02657.1 - 3.7e-14 52.8 0.0 3.7e-05 23.9 0.0 4.8 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXT02657.1 - 9.8e-07 27.8 0.4 0.0047 15.6 0.1 3.9 3 1 0 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KXT02657.1 - 1.1e-05 24.5 0.1 0.5 9.1 0.1 3.6 3 1 0 3 3 3 3 Nup133 N terminal like Acyl-CoA_dh_1 PF00441.24 KXT02658.1 - 2.4e-37 128.5 1.2 3.4e-37 128.0 0.4 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KXT02658.1 - 8.9e-32 110.1 0.2 2.2e-31 108.8 0.2 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KXT02658.1 - 3.5e-28 97.6 0.2 6.4e-28 96.8 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KXT02658.1 - 1.6e-12 47.8 0.0 4e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KXT02658.1 - 0.0042 16.8 0.2 0.012 15.2 0.2 1.7 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Pec_lyase_C PF00544.19 KXT02659.1 - 2.8e-13 49.9 5.0 8.2e-12 45.2 5.0 2.2 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KXT02659.1 - 0.0029 17.5 6.8 0.01 15.7 5.6 2.0 1 1 1 2 2 2 2 Right handed beta helix region Glyco_hydro_47 PF01532.20 KXT02660.1 - 4.7e-187 622.4 1.2 5.7e-187 622.2 1.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Ferrochelatase PF00762.19 KXT02661.1 - 7.1e-98 327.6 0.0 8.6e-98 327.3 0.0 1.1 1 0 0 1 1 1 1 Ferrochelatase 4HB_MCP_1 PF12729.7 KXT02662.1 - 0.34 10.4 4.1 1 8.8 0.6 3.6 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction DUF1835 PF08874.10 KXT02663.1 - 0.051 13.8 0.7 0.092 12.9 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1835) Mtd_N PF18454.1 KXT02663.1 - 0.14 12.2 0.0 0.38 10.8 0.0 1.7 1 0 0 1 1 1 0 Major tropism determinant N-terminal domain VIR_N PF15912.5 KXT02663.1 - 0.72 9.4 8.9 1.1 8.8 8.9 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal PPI_Ypi1 PF07491.11 KXT02664.1 - 4.2e-25 87.3 0.3 8.9e-25 86.3 0.3 1.6 1 0 0 1 1 1 1 Protein phosphatase inhibitor Catalase PF00199.19 KXT02665.1 - 7.8e-172 571.7 0.0 1.1e-171 571.2 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KXT02665.1 - 5.9e-16 58.4 0.0 1.8e-15 56.9 0.0 1.9 1 0 0 1 1 1 1 Catalase-related immune-responsive Fungal_trans_2 PF11951.8 KXT02665.1 - 1.3e-13 50.6 3.2 3.5e-13 49.1 3.2 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zip PF02535.22 KXT02666.1 - 1.5e-30 106.6 15.2 1.4e-20 73.8 7.6 2.1 2 0 0 2 2 2 2 ZIP Zinc transporter EOS1 PF12326.8 KXT02666.1 - 0.0053 16.7 0.6 0.011 15.6 0.1 1.8 2 0 0 2 2 2 1 N-glycosylation protein PHO4 PF01384.20 KXT02666.1 - 1.5 7.8 10.1 0.31 10.0 3.9 2.2 1 1 1 2 2 2 0 Phosphate transporter family DUF4834 PF16118.5 KXT02666.1 - 3.9 8.5 8.1 2.3 9.2 2.2 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) DENN PF02141.21 KXT02667.1 - 9.6e-55 185.4 0.0 3.6e-54 183.6 0.0 1.9 2 0 0 2 2 2 1 DENN (AEX-3) domain uDENN PF03456.18 KXT02667.1 - 4.9e-14 52.8 0.2 1.1e-13 51.7 0.2 1.6 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 KXT02667.1 - 6e-14 51.8 2.9 1.7e-13 50.3 2.0 2.3 2 0 0 2 2 2 1 dDENN domain C1_1 PF00130.22 KXT02667.1 - 0.00094 19.0 11.0 0.0019 18.0 11.0 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KXT02667.1 - 0.053 13.8 10.5 0.042 14.2 8.0 2.0 2 0 0 2 2 2 0 C1 domain PHD_2 PF13831.6 KXT02667.1 - 0.056 13.0 1.2 0.14 11.8 1.2 1.7 1 0 0 1 1 1 0 PHD-finger PHD PF00628.29 KXT02667.1 - 0.42 10.5 12.3 0.23 11.4 9.0 2.2 2 0 0 2 2 2 0 PHD-finger THOC7 PF05615.13 KXT02668.1 - 0.00077 19.7 2.5 0.001 19.3 2.5 1.2 1 0 0 1 1 1 1 Tho complex subunit 7 TMEM237 PF15383.6 KXT02668.1 - 0.083 12.0 0.2 0.1 11.7 0.2 1.2 1 0 0 1 1 1 0 Transmembrane protein 237 Fungal_trans_2 PF11951.8 KXT02669.1 - 1.2e-06 27.6 0.0 2e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 KXT02670.1 - 1.2e-06 27.6 0.0 1.9e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT02671.1 - 5.6e-09 36.0 9.5 1.2e-08 34.9 9.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXT02671.1 - 1.4e-06 27.4 0.0 2.1e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain COesterase PF00135.28 KXT02674.1 - 1.1e-82 278.6 0.0 1.5e-82 278.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXT02674.1 - 9.9e-06 25.6 1.1 0.0001 22.2 0.4 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXT02674.1 - 0.16 11.5 0.6 0.27 10.7 0.6 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Shugoshin_N PF07558.11 KXT02675.1 - 9.4e-13 47.8 6.9 2.2e-12 46.6 6.9 1.6 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.11 KXT02675.1 - 4.8e-11 42.2 5.2 4.8e-11 42.2 5.2 2.9 3 0 0 3 3 3 1 Shugoshin C terminus CCDC85 PF10226.9 KXT02675.1 - 0.092 12.4 2.7 0.088 12.5 0.8 1.9 2 0 0 2 2 2 0 CCDC85 family DUF1465 PF07323.12 KXT02675.1 - 0.42 10.5 4.7 0.68 9.8 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) DUF5518 PF17647.1 KXT02676.1 - 0.29 11.3 6.5 0.54 10.4 6.5 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5518) DUF2388 PF09498.10 KXT02677.1 - 0.024 14.6 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2388) Carboxyl_trans PF01039.22 KXT02679.1 - 3.9e-138 461.2 0.0 5.7e-138 460.6 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain ATG16 PF08614.11 KXT02679.1 - 0.0041 17.4 3.8 0.0041 17.4 3.8 2.6 3 0 0 3 3 3 1 Autophagy protein 16 (ATG16) MdcE PF06833.11 KXT02679.1 - 0.026 14.0 0.1 3.5 7.0 0.0 2.6 2 0 0 2 2 2 0 Malonate decarboxylase gamma subunit (MdcE) APG6_N PF17675.1 KXT02679.1 - 0.6 10.6 4.2 1.4 9.4 4.2 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF812 PF05667.11 KXT02679.1 - 0.69 8.7 7.4 0.028 13.3 1.9 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF812) p450 PF00067.22 KXT02680.1 - 7e-46 156.9 0.0 1e-45 156.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_76 PF03663.14 KXT02681.1 - 3.6e-134 447.9 13.1 4.4e-134 447.6 13.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KXT02681.1 - 0.049 12.7 12.5 0.087 11.9 0.8 2.9 2 1 0 3 3 3 0 Glycosyl Hydrolase Family 88 RINGv PF12906.7 KXT02682.1 - 1.8e-16 60.0 9.3 3.5e-16 59.0 9.3 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KXT02682.1 - 0.0018 18.6 9.9 0.0036 17.6 9.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 KXT02682.1 - 0.13 12.3 2.8 0.35 11.0 2.8 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KXT02682.1 - 0.19 11.6 6.0 0.41 10.5 6.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ubiquitin PF00240.23 KXT02684.1 - 2.4e-95 312.3 10.9 1.6e-33 114.2 0.6 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.8 KXT02684.1 - 3e-44 148.7 10.7 1e-15 57.3 0.7 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KXT02684.1 - 4.7e-18 65.4 4.9 0.00021 21.7 0.1 4.6 2 2 1 3 3 3 3 Ubiquitin-like domain TBK1_ULD PF18396.1 KXT02684.1 - 5.9e-13 48.6 0.1 0.013 15.4 0.0 3.2 2 1 0 3 3 3 3 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 KXT02684.1 - 2.1e-12 47.3 1.2 0.012 16.0 0.1 3.1 2 1 1 3 3 3 3 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KXT02684.1 - 2.9e-11 43.5 0.8 0.017 15.2 0.1 3.8 2 2 1 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KXT02684.1 - 1.6e-09 38.2 0.6 0.04 14.5 0.1 3.1 1 1 2 3 3 3 3 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 KXT02684.1 - 7.6e-06 25.9 11.0 9.8 6.3 0.2 5.3 5 0 0 5 5 5 0 Ubiquitin-like domain Sde2_N_Ubi PF13019.6 KXT02684.1 - 4.3e-05 23.4 0.3 0.33 10.8 0.0 3.0 1 1 2 3 3 3 2 Silencing defective 2 N-terminal ubiquitin domain DUF2870 PF11069.8 KXT02684.1 - 0.00015 22.1 0.0 11 6.4 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2870) DUF3861 PF12977.7 KXT02684.1 - 0.0041 17.3 0.5 7.5 6.8 0.0 3.0 3 0 0 3 3 3 1 Domain of Unknown Function with PDB structure (DUF3861) TmoB PF06234.12 KXT02684.1 - 0.0043 17.1 0.5 27 5.0 0.0 3.7 2 2 1 3 3 3 0 Toluene-4-monooxygenase system protein B (TmoB) TRCF PF03461.15 KXT02684.1 - 0.014 15.8 0.4 8.7 6.8 0.0 3.1 3 0 0 3 3 3 0 TRCF domain ACT_5 PF13710.6 KXT02684.1 - 0.017 15.0 2.0 6.2 6.7 0.0 2.9 3 0 0 3 3 3 0 ACT domain Raf1_HTH PF18579.1 KXT02684.1 - 0.023 14.4 0.0 64 3.3 0.0 3.2 3 0 0 3 3 3 0 Rubisco accumulation factor 1 helix turn helix domain DUF969 PF06149.12 KXT02684.1 - 0.025 14.0 0.0 13 5.2 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF969) FERM_f0 PF16511.5 KXT02684.1 - 0.045 14.0 2.8 67 3.9 0.1 4.2 3 3 0 3 3 3 0 N-terminal or F0 domain of Talin-head FERM YcgR_2 PF12945.7 KXT02684.1 - 0.083 13.0 1.3 17 5.6 0.1 2.6 3 0 0 3 3 3 0 Flagellar protein YcgR Big_7 PF17957.1 KXT02684.1 - 0.084 13.6 0.1 29 5.5 0.0 2.5 3 0 0 3 3 2 0 Bacterial Ig domain ProRS-C_2 PF09181.10 KXT02684.1 - 0.089 12.9 1.8 65 3.8 0.1 3.1 3 0 0 3 3 3 0 Prolyl-tRNA synthetase, C-terminal DUF1940 PF09155.10 KXT02684.1 - 0.17 12.0 1.6 70 3.5 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1940) Tash_PEST PF07708.11 KXT02684.1 - 0.31 11.3 9.6 4.1 7.7 1.5 2.5 2 0 0 2 2 2 0 Tash protein PEST motif DMA PF03474.14 KXT02684.1 - 0.68 9.6 2.8 65 3.2 0.0 3.2 3 0 0 3 3 3 0 DMRTA motif Plexin_cytopl PF08337.12 KXT02684.1 - 0.73 8.4 8.0 9.8 4.7 0.5 3.5 2 1 0 3 3 3 0 Plexin cytoplasmic RasGAP domain Ubiq_cyt_C_chap PF03981.12 KXT02685.1 - 1.1e-34 119.5 0.5 1.7e-34 118.9 0.5 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Ku PF02735.16 KXT02686.1 - 7e-42 143.5 0.0 3.3e-40 138.0 0.0 2.2 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 KXT02686.1 - 1e-29 103.9 0.0 1.6e-29 103.3 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 KXT02686.1 - 4.5e-27 94.6 0.2 1.3e-26 93.1 0.2 1.8 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 KXT02686.1 - 1.4e-08 34.3 0.0 2.2e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 SAP domain HeH PF12949.7 KXT02686.1 - 0.024 14.4 0.0 0.053 13.3 0.0 1.6 1 0 0 1 1 1 0 HeH/LEM domain VWA_2 PF13519.6 KXT02686.1 - 0.025 15.2 0.1 1.7 9.4 0.0 2.7 2 0 0 2 2 2 0 von Willebrand factor type A domain Sec61_beta PF03911.16 KXT02687.1 - 1.3e-17 63.6 1.7 2e-17 62.9 1.7 1.3 1 0 0 1 1 1 1 Sec61beta family SET PF00856.28 KXT02688.1 - 1.2e-14 55.1 0.0 6.3e-13 49.5 0.0 2.1 1 1 0 1 1 1 1 SET domain SAF PF08666.12 KXT02688.1 - 0.013 16.1 0.1 9.4 6.9 0.0 2.3 2 0 0 2 2 2 0 SAF domain RRM_1 PF00076.22 KXT02689.1 - 8e-38 128.1 0.1 7.5e-12 44.9 0.1 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXT02689.1 - 3.3e-14 52.5 0.1 0.0061 16.4 0.0 4.6 5 0 0 5 5 5 3 Occluded RNA-recognition motif RRM PF10378.9 KXT02689.1 - 1.4e-07 31.1 9.8 1.4e-07 31.1 9.8 4.2 3 1 0 3 3 3 1 Putative RRM domain DUF4523 PF15023.6 KXT02689.1 - 2.7e-05 24.0 0.0 0.44 10.4 0.0 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF4523) RRM_7 PF16367.5 KXT02689.1 - 3.1e-05 24.0 0.0 0.18 12.0 0.0 3.7 3 0 0 3 3 3 2 RNA recognition motif RRM_3 PF08777.11 KXT02689.1 - 0.00024 21.1 0.1 0.71 10.0 0.1 3.1 3 0 0 3 3 3 2 RNA binding motif Nup35_RRM_2 PF14605.6 KXT02689.1 - 0.064 13.3 0.0 40 4.3 0.0 3.3 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Glyco_trans_4_3 PF12000.8 KXT02689.1 - 0.14 11.8 1.3 0.37 10.5 1.3 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 4 group RNA_bind PF08675.11 KXT02689.1 - 0.19 11.8 0.3 1.1 9.3 0.0 2.4 3 0 0 3 3 3 0 RNA binding domain eIF3g PF12353.8 KXT02690.1 - 0.14 12.5 0.1 0.23 11.8 0.1 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G Ribosomal_L32p PF01783.23 KXT02691.1 - 1.4e-13 50.8 6.0 2.4e-13 50.1 6.0 1.4 1 0 0 1 1 1 1 Ribosomal L32p protein family DUF5089 PF17002.5 KXT02691.1 - 0.011 15.6 0.8 0.018 15.0 0.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5089) zinc-ribbons_6 PF07191.12 KXT02691.1 - 0.057 13.4 1.1 0.11 12.5 1.1 1.5 1 1 0 1 1 1 0 zinc-ribbons PolC_DP2 PF03833.13 KXT02691.1 - 0.087 10.7 0.1 0.098 10.5 0.1 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Autophagy_N PF03986.13 KXT02692.1 - 6.4e-41 139.5 0.1 6.4e-41 139.5 0.1 3.5 3 1 0 3 3 3 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_C PF10381.9 KXT02692.1 - 1.7e-15 56.2 0.6 2.7e-15 55.5 0.6 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Autophagy_act_C PF03987.15 KXT02692.1 - 5.4e-14 52.5 0.1 1.1e-13 51.5 0.1 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain ATG16 PF08614.11 KXT02692.1 - 0.0008 19.7 13.1 0.0008 19.7 13.1 3.6 2 1 2 4 4 3 1 Autophagy protein 16 (ATG16) TPD52 PF04201.15 KXT02692.1 - 0.0014 18.3 3.6 0.0014 18.3 3.6 2.3 2 1 1 3 3 3 1 Tumour protein D52 family Rootletin PF15035.6 KXT02692.1 - 0.017 15.2 1.4 0.017 15.2 1.4 3.6 2 1 1 3 3 2 0 Ciliary rootlet component, centrosome cohesion FlaC_arch PF05377.11 KXT02692.1 - 0.16 12.3 1.7 17 5.9 0.0 3.1 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Spectrin PF00435.21 KXT02692.1 - 0.51 10.8 21.2 0.37 11.3 9.7 3.4 2 1 0 2 2 2 0 Spectrin repeat DUF720 PF05302.11 KXT02692.1 - 1.1 9.1 11.8 0.26 11.1 5.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF720) GAS PF13851.6 KXT02692.1 - 1.2 8.5 35.0 1.8 7.9 7.0 3.4 1 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 KXT02692.1 - 1.2 9.5 34.5 2.5 8.5 11.8 2.7 1 1 1 2 2 2 0 Fez1 DUF1664 PF07889.12 KXT02692.1 - 3 7.9 14.9 2.8 8.0 1.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF4446 PF14584.6 KXT02692.1 - 3.1 7.8 12.2 3.5 7.6 0.3 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) Plk4_PB2 PF18409.1 KXT02692.1 - 3.7 8.3 7.6 1.1 10.0 1.1 3.0 1 1 2 3 3 3 0 Polo-like Kinase 4 Polo Box 2 Tropomyosin PF00261.20 KXT02692.1 - 5 6.4 36.0 8.3 5.7 4.4 2.4 1 1 1 2 2 2 0 Tropomyosin FliJ PF02050.16 KXT02692.1 - 5 7.4 33.5 0.78 10.0 8.9 3.5 1 1 2 3 3 3 0 Flagellar FliJ protein KxDL PF10241.9 KXT02692.1 - 5.5 7.3 15.8 11 6.4 0.3 3.7 3 0 0 3 3 3 0 Uncharacterized conserved protein TMF_TATA_bd PF12325.8 KXT02692.1 - 7.4 6.8 26.2 3.6 7.8 6.4 3.1 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding zf-C4H2 PF10146.9 KXT02692.1 - 8.2 6.7 25.7 40 4.4 7.4 3.7 1 1 2 3 3 3 0 Zinc finger-containing protein DUF974 PF06159.13 KXT02693.1 - 3.1e-78 263.0 0.1 3.7e-78 262.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF974) DUF1242 PF06842.12 KXT02694.1 - 7.8e-18 64.0 1.2 1.1e-17 63.5 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) DUF418 PF04235.12 KXT02694.1 - 0.022 14.7 0.2 0.022 14.7 0.2 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF418) DUF624 PF04854.14 KXT02694.1 - 0.025 14.7 0.1 0.025 14.7 0.1 1.3 2 0 0 2 2 2 0 Protein of unknown function, DUF624 UcrQ PF02939.16 KXT02701.1 - 2.1e-33 114.1 0.1 2.5e-33 113.8 0.1 1.1 1 0 0 1 1 1 1 UcrQ family Pre-PUA PF17832.1 KXT02702.1 - 1.6e-25 89.6 0.3 2.2e-25 89.1 0.3 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 KXT02702.1 - 8.1e-13 48.1 0.0 2.9e-12 46.4 0.0 1.8 1 1 0 1 1 1 1 PUA domain DUF1947 PF09183.10 KXT02702.1 - 0.067 13.5 0.0 0.13 12.5 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1947) zf-U1 PF06220.12 KXT02703.1 - 2.3e-06 27.3 0.3 2.3e-06 27.3 0.3 1.6 2 0 0 2 2 2 1 U1 zinc finger TetR_C_6 PF13977.6 KXT02703.1 - 0.01 16.1 0.2 0.068 13.4 0.0 2.4 2 1 0 2 2 2 1 BetI-type transcriptional repressor, C-terminal PaaA_PaaC PF05138.12 KXT02703.1 - 0.033 13.3 0.2 0.044 13.0 0.2 1.2 1 0 0 1 1 1 0 Phenylacetic acid catabolic protein DUF4554 PF15091.6 KXT02703.1 - 0.055 12.3 2.2 0.09 11.7 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) DUF2052 PF09747.9 KXT02703.1 - 0.14 12.2 9.8 0.1 12.7 2.4 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) SAPI PF16560.5 KXT02703.1 - 0.16 11.5 0.0 0.35 10.4 0.0 1.5 1 0 0 1 1 1 0 Putative mobile pathogenicity island PCI PF01399.27 KXT02704.1 - 2.1e-14 53.9 0.0 6.6e-14 52.3 0.0 1.9 1 0 0 1 1 1 1 PCI domain RPN7 PF10602.9 KXT02704.1 - 6.9e-05 22.6 0.8 6.9e-05 22.6 0.8 1.6 2 0 0 2 2 2 1 26S proteasome subunit RPN7 TPR_19 PF14559.6 KXT02704.1 - 0.00066 20.1 0.4 1 9.9 0.1 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat RhoGAP PF00620.27 KXT02705.1 - 2.1e-38 131.5 0.0 3.4e-38 130.9 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Peptidase_M22 PF00814.25 KXT02707.1 - 3.9e-49 167.8 0.0 2.5e-48 165.1 0.0 2.2 1 1 0 1 1 1 1 Glycoprotease family DUF4048 PF13257.6 KXT02707.1 - 0.00017 21.6 0.0 0.00027 20.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4048) YycC PF14174.6 KXT02707.1 - 0.0095 15.7 0.3 0.02 14.7 0.3 1.5 1 0 0 1 1 1 1 YycC-like protein COPIIcoated_ERV PF07970.12 KXT02708.1 - 2.3e-31 109.4 0.0 3.4e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KXT02708.1 - 8.5e-27 93.3 0.0 1.4e-26 92.7 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF4245 PF14030.6 KXT02708.1 - 0.099 12.6 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4245) Kri1_C PF12936.7 KXT02709.1 - 9e-30 102.7 0.0 9e-30 102.7 0.0 4.6 3 1 1 4 4 4 1 KRI1-like family C-terminal Kri1 PF05178.12 KXT02709.1 - 2.4e-28 98.7 14.2 2.4e-28 98.7 14.2 5.7 5 2 1 6 6 6 1 KRI1-like family tRNA-synt_2b PF00587.25 KXT02710.1 - 2e-34 119.1 0.0 3.3e-34 118.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KXT02710.1 - 6.2e-11 42.3 0.0 1.2e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain SURF4 PF02077.15 KXT02711.1 - 2.3e-93 312.6 7.5 2.6e-93 312.5 7.5 1.0 1 0 0 1 1 1 1 SURF4 family DUF3325 PF11804.8 KXT02711.1 - 0.068 13.3 0.9 0.068 13.3 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3325) DNA_ligase_A_M PF01068.21 KXT02712.1 - 1e-58 198.4 0.6 3.1e-46 157.6 0.2 2.4 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KXT02712.1 - 6.1e-44 150.4 0.0 1.2e-43 149.5 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KXT02712.1 - 2.3e-28 98.7 0.0 9.4e-28 96.7 0.0 2.1 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region PWWP PF00855.17 KXT02712.1 - 0.069 13.6 1.0 0.41 11.1 1.0 2.4 1 0 0 1 1 1 0 PWWP domain DNA_ligase_OB_2 PF14743.6 KXT02712.1 - 0.12 12.4 0.0 15 5.7 0.1 2.6 2 0 0 2 2 2 0 DNA ligase OB-like domain Nup84_Nup100 PF04121.13 KXT02713.1 - 5.3e-164 547.2 7.5 6.4e-164 546.9 7.5 1.1 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 PK PF00224.21 KXT02714.1 - 1.1e-172 573.7 5.8 1.4e-172 573.4 5.8 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KXT02714.1 - 2.2e-38 131.1 0.2 7.5e-38 129.4 0.0 2.1 3 0 0 3 3 3 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KXT02714.1 - 0.00018 20.7 0.8 0.00046 19.4 0.2 1.8 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family DUF218 PF02698.17 KXT02714.1 - 0.15 12.1 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 DUF218 domain DUF3336 PF11815.8 KXT02715.1 - 3.6e-26 91.5 0.6 6.2e-25 87.5 0.4 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KXT02715.1 - 1.1e-12 48.6 0.1 3.1e-12 47.1 0.0 1.9 2 0 0 2 2 2 1 Patatin-like phospholipase DUF2630 PF10944.8 KXT02715.1 - 0.017 15.6 0.1 0.055 13.9 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2630) DUF3336 PF11815.8 KXT02716.1 - 4.6e-47 159.2 2.3 7.1e-47 158.6 2.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KXT02716.1 - 5.1e-17 62.7 0.6 6.4e-16 59.1 0.6 2.5 1 1 0 1 1 1 1 Patatin-like phospholipase DUF1713 PF08213.11 KXT02717.1 - 3.8e-11 42.7 21.3 3.8e-11 42.7 21.3 2.1 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) Pet20 PF08692.10 KXT02717.1 - 0.00025 21.7 0.6 0.002 18.8 0.0 2.6 3 0 0 3 3 3 1 Mitochondrial protein Pet20 PBP_N PF17093.5 KXT02717.1 - 0.07 13.4 0.3 0.07 13.4 0.3 2.6 2 1 0 3 3 3 0 Penicillin-binding protein N-terminus Red1 PF07964.11 KXT02717.1 - 6.6 4.8 10.3 13 3.9 10.3 1.3 1 0 0 1 1 1 0 Rec10 / Red1 Homeodomain PF00046.29 KXT02718.1 - 2.6e-13 49.6 0.2 6.3e-13 48.4 0.2 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KXT02718.1 - 0.014 15.3 1.0 0.13 12.2 0.1 2.5 2 0 0 2 2 2 0 Homeobox KN domain CK_II_beta PF01214.18 KXT02719.1 - 1.7e-77 259.4 0.6 2.1e-77 259.0 0.6 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Astro_capsid_p PF12226.8 KXT02719.1 - 0.028 13.6 0.9 0.041 13.0 0.9 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CxC5 PF18718.1 KXT02719.1 - 0.081 13.0 0.4 0.18 11.9 0.4 1.6 1 0 0 1 1 1 0 CxC5 like cysteine cluster associated with KDZ transposases Tocopherol_cycl PF14249.6 KXT02721.1 - 0.0034 16.6 0.9 0.0085 15.3 0.8 2.0 1 1 1 2 2 2 1 Tocopherol cyclase AhpC-TSA_2 PF13911.6 KXT02722.1 - 3.8e-18 65.7 0.0 5.7e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 KXT02722.1 - 7.2e-07 29.2 0.0 1e-06 28.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KXT02722.1 - 0.00091 19.0 0.0 0.0014 18.4 0.0 1.2 1 0 0 1 1 1 1 Redoxin Cid2 PF09774.9 KXT02724.1 - 5e-52 176.6 0.1 7.1e-52 176.0 0.1 1.2 1 0 0 1 1 1 1 Caffeine-induced death protein 2 Fapy_DNA_glyco PF01149.24 KXT02726.1 - 2.9e-28 98.8 1.0 3.8e-28 98.4 0.0 1.7 2 0 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 KXT02726.1 - 1.8e-22 79.1 0.0 3.5e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Ribosomal_S13 PF00416.22 KXT02726.1 - 0.027 14.9 0.5 0.06 13.7 0.0 1.8 2 0 0 2 2 2 0 Ribosomal protein S13/S18 Tropomyosin PF00261.20 KXT02727.1 - 0.0041 16.5 12.8 0.0041 16.5 12.8 5.2 1 1 3 5 5 5 1 Tropomyosin Tropomyosin_1 PF12718.7 KXT02727.1 - 0.0064 16.6 16.4 0.0064 16.6 16.4 5.5 2 1 3 7 7 7 2 Tropomyosin like Shugoshin_N PF07558.11 KXT02727.1 - 0.1 12.5 9.6 3.2 7.7 0.1 4.4 5 0 0 5 5 5 0 Shugoshin N-terminal coiled-coil region ATG16 PF08614.11 KXT02727.1 - 0.24 11.6 71.5 4.2 7.5 21.9 4.5 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) TMEM192 PF14802.6 KXT02727.1 - 1.4 7.9 3.4 2.9 6.9 3.4 1.5 1 0 0 1 1 1 0 TMEM192 family DUF1664 PF07889.12 KXT02727.1 - 4.9 7.2 17.3 4.9 7.2 0.4 4.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Glyoxalase PF00903.25 KXT02728.1 - 1.8e-09 37.8 3.2 6.4e-08 32.8 2.2 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF3395 PF11875.8 KXT02729.1 - 0.0022 17.9 4.7 0.0022 17.9 4.7 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF3395) YqfD PF06898.11 KXT02729.1 - 1.2 7.9 5.7 2.2 7.0 5.7 1.4 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD Glyco_transf_34 PF05637.12 KXT02730.1 - 3.8e-65 220.0 0.1 9.4e-65 218.7 0.1 1.6 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Glutaredoxin PF00462.24 KXT02730.1 - 6.8e-20 71.0 0.0 4.8e-18 65.1 0.0 2.7 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 KXT02730.1 - 1.3e-14 54.0 0.0 2.8e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KXT02730.1 - 0.00065 20.0 0.0 0.034 14.5 0.0 2.6 1 1 1 2 2 2 1 Thioredoxin-like OST3_OST6 PF04756.13 KXT02730.1 - 0.0071 15.7 0.7 0.033 13.5 0.0 2.1 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family SMP PF04927.12 KXT02730.1 - 4.7 7.8 7.6 0.89 10.1 0.2 2.5 2 0 0 2 2 2 0 Seed maturation protein SPC25 PF06703.11 KXT02731.1 - 2.5e-52 177.0 0.3 3.3e-52 176.5 0.3 1.2 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Phage_TTP_11 PF16460.5 KXT02731.1 - 0.6 10.0 3.8 3.3 7.5 1.6 2.6 2 1 1 3 3 3 0 Phage tail tube, TTP, lambda-like Translin PF01997.16 KXT02732.1 - 3.4e-45 154.5 0.0 4.3e-45 154.2 0.0 1.1 1 0 0 1 1 1 1 Translin family Ribosomal_S13_N PF08069.12 KXT02732.1 - 0.2 11.7 0.6 4.3 7.5 0.0 2.7 2 1 1 3 3 3 0 Ribosomal S13/S15 N-terminal domain 4HBT PF03061.22 KXT02733.1 - 2e-06 28.1 0.0 3.5e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 KXT02733.1 - 0.043 14.1 0.0 0.054 13.7 0.0 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily Protoglobin PF11563.8 KXT02733.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.5 2 0 0 2 2 2 0 Protoglobin 4HBT PF03061.22 KXT02735.1 - 2e-06 28.1 0.0 3.5e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 KXT02735.1 - 0.043 14.1 0.0 0.054 13.7 0.0 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily Protoglobin PF11563.8 KXT02735.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.5 2 0 0 2 2 2 0 Protoglobin 4HBT PF03061.22 KXT02736.1 - 2e-06 28.1 0.0 3.5e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 KXT02736.1 - 0.043 14.1 0.0 0.054 13.7 0.0 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily Protoglobin PF11563.8 KXT02736.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.5 2 0 0 2 2 2 0 Protoglobin Methyltransf_16 PF10294.9 KXT02737.1 - 3.4e-13 49.7 0.0 4.5e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KXT02737.1 - 0.00016 21.5 0.0 0.00023 21.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 KXT02737.1 - 0.00027 20.2 0.0 0.0005 19.3 0.0 1.4 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_25 PF13649.6 KXT02737.1 - 0.0031 18.2 0.0 0.0078 16.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain GidB PF02527.15 KXT02737.1 - 0.016 14.6 0.0 0.028 13.7 0.0 1.4 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G RrnaAD PF00398.20 KXT02737.1 - 0.04 13.0 0.0 0.063 12.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase NDUFB10 PF10249.9 KXT02738.1 - 0.00073 20.0 0.1 0.00082 19.9 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 HWE_HK PF07536.14 KXT02738.1 - 0.1 13.3 0.0 0.17 12.6 0.0 1.3 1 0 0 1 1 1 0 HWE histidine kinase PDEase_I PF00233.19 KXT02741.1 - 8.2e-69 231.9 0.0 1.2e-68 231.4 0.0 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase MARVEL PF01284.23 KXT02742.1 - 0.024 14.7 17.0 0.07 13.2 16.9 1.8 1 1 0 1 1 1 0 Membrane-associating domain MARVEL PF01284.23 KXT02745.1 - 0.024 14.7 17.0 0.07 13.2 16.9 1.8 1 1 0 1 1 1 0 Membrane-associating domain Rcd1 PF04078.13 KXT02746.1 - 2.8e-125 416.8 2.7 3.3e-125 416.6 2.7 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Androgen_recep PF02166.16 KXT02746.1 - 0.082 11.7 8.8 0.13 11.1 8.8 1.3 1 0 0 1 1 1 0 Androgen receptor zf-Tim10_DDP PF02953.15 KXT02747.1 - 2.1e-21 75.3 4.4 2.8e-21 74.9 4.4 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 KXT02747.1 - 0.03 14.0 4.5 0.2 11.4 3.2 2.1 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Transketolase_N PF00456.21 KXT02748.1 - 3.8e-153 509.3 0.1 4.9e-153 509.0 0.1 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KXT02748.1 - 8.8e-46 155.8 0.0 1.4e-45 155.1 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KXT02748.1 - 1.7e-13 50.5 0.0 3.4e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 KXT02748.1 - 0.0018 17.5 0.0 0.003 16.8 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 KXT02748.1 - 0.0052 15.8 0.1 0.008 15.2 0.1 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component GtrA PF04138.14 KXT02748.1 - 0.13 12.5 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 GtrA-like protein Beta_elim_lyase PF01212.21 KXT02748.1 - 0.16 11.2 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase JIP_LZII PF16471.5 KXT02749.1 - 0.015 15.5 0.3 0.015 15.5 0.3 9.3 8 3 2 10 10 10 0 JNK-interacting protein leucine zipper II DEAD PF00270.29 KXT02750.1 - 1.5e-41 142.1 0.0 6.3e-41 140.0 0.0 2.1 2 1 1 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXT02750.1 - 2.2e-30 105.3 0.0 5.6e-30 103.9 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXT02750.1 - 7.9e-05 22.7 0.0 0.00022 21.3 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 KXT02750.1 - 0.013 14.3 0.0 0.018 13.8 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain SWI2_SNF2 PF18766.1 KXT02750.1 - 0.2 11.3 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 SWI2/SNF2 ATPase Band_7 PF01145.25 KXT02751.1 - 1.9e-24 86.6 7.1 3.3e-24 85.9 7.0 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 KXT02751.1 - 4.8e-05 22.6 4.5 6.9e-05 22.1 4.5 1.3 1 0 0 1 1 1 1 SigmaW regulon antibacterial MgtE_N PF03448.17 KXT02751.1 - 0.056 14.0 1.7 12 6.6 0.1 2.3 2 0 0 2 2 2 0 MgtE intracellular N domain GatB_Yqey PF02637.18 KXT02751.1 - 0.082 12.8 1.4 0.15 11.9 1.3 1.5 1 1 0 1 1 1 0 GatB domain F-box-like PF12937.7 KXT02752.1 - 0.0013 18.6 0.1 0.0027 17.5 0.1 1.6 1 0 0 1 1 1 1 F-box-like Actin PF00022.19 KXT02753.1 - 8.3e-110 367.2 0.0 3.4e-109 365.1 0.0 1.8 1 1 0 1 1 1 1 Actin SUN PF03856.13 KXT02753.1 - 1.2e-92 309.8 18.7 1.9e-92 309.2 18.7 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) ApeC PF16977.5 KXT02753.1 - 0.063 13.2 0.1 0.063 13.2 0.1 1.9 2 0 0 2 2 2 0 C-terminal domain of apextrin RIC1 PF07064.13 KXT02754.1 - 2.5e-81 272.8 0.0 3.5e-81 272.3 0.0 1.2 1 0 0 1 1 1 1 RIC1 WD40 PF00400.32 KXT02754.1 - 0.28 12.1 1.1 48 5.0 0.3 3.9 2 1 0 2 2 2 0 WD domain, G-beta repeat Brix PF04427.18 KXT02755.1 - 9.1e-39 133.6 0.1 1.2e-38 133.1 0.1 1.2 1 0 0 1 1 1 1 Brix domain Fungal_trans_2 PF11951.8 KXT02756.1 - 2.8e-11 42.8 0.7 7.3e-10 38.2 0.1 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain CBF PF03914.17 KXT02758.1 - 1.7e-56 190.9 0.1 4.4e-56 189.6 0.1 1.8 1 0 0 1 1 1 1 CBF/Mak21 family Adaptin_N PF01602.20 KXT02758.1 - 0.0013 17.4 0.1 0.027 13.0 0.0 2.1 2 0 0 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 KXT02758.1 - 0.0045 17.0 0.7 0.021 14.9 0.0 2.1 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 DUF4201 PF13870.6 KXT02760.1 - 0.049 13.4 7.4 0.1 12.3 7.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Fib_alpha PF08702.10 KXT02760.1 - 0.62 10.3 3.7 9.3 6.4 0.6 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family adh_short PF00106.25 KXT02763.1 - 1.1e-13 51.1 0.2 1.3e-13 50.9 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT02763.1 - 1.9e-09 37.5 0.0 2.1e-09 37.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT02763.1 - 3.5e-08 33.6 0.2 4.4e-08 33.3 0.2 1.0 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXT02763.1 - 0.00014 21.4 0.0 0.00016 21.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KXT02763.1 - 0.0021 18.1 0.1 0.0023 18.0 0.1 1.1 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 KXT02763.1 - 0.011 15.6 0.2 0.014 15.3 0.2 1.1 1 0 0 1 1 1 0 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KXT02763.1 - 0.029 14.6 0.1 0.034 14.4 0.1 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 KXT02763.1 - 0.031 13.9 0.3 0.035 13.6 0.3 1.0 1 0 0 1 1 1 0 NmrA-like family 3HBOH PF10605.9 KXT02763.1 - 0.046 12.0 0.1 0.049 11.9 0.1 1.0 1 0 0 1 1 1 0 3HB-oligomer hydrolase (3HBOH) 3Beta_HSD PF01073.19 KXT02763.1 - 0.051 12.6 0.1 0.061 12.3 0.1 1.0 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KXT02763.1 - 0.055 12.9 0.1 0.081 12.3 0.1 1.3 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KXT02763.1 - 0.097 11.8 0.1 0.12 11.5 0.1 1.0 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RIFIN PF02009.16 KXT02764.1 - 5.8e-06 26.4 0.1 8.6e-06 25.9 0.1 1.2 1 0 0 1 1 1 1 Rifin CFEM PF05730.11 KXT02764.1 - 0.00019 21.4 8.8 0.00043 20.3 8.8 1.5 1 0 0 1 1 1 1 CFEM domain SKG6 PF08693.10 KXT02764.1 - 0.0049 16.3 2.7 0.0093 15.4 2.7 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain EphA2_TM PF14575.6 KXT02764.1 - 0.025 15.5 0.0 0.073 14.0 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 KXT02764.1 - 0.088 12.7 9.1 0.93 9.4 9.1 2.3 1 1 0 1 1 1 0 TMEM154 protein family Mucin PF01456.17 KXT02764.1 - 2.7 8.0 26.8 0.061 13.3 18.3 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein PIG-F PF06699.11 KXT02765.1 - 1.6e-65 220.7 6.9 2.2e-65 220.2 6.9 1.2 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Bacteriocin_IIc PF10439.9 KXT02765.1 - 0.01 15.9 0.3 0.021 14.9 0.3 1.5 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_Omp PF13488.6 KXT02765.1 - 0.54 10.3 5.4 3.7 7.6 5.4 2.0 1 1 0 1 1 1 0 Glycine zipper Gly-zipper_YMGG PF13441.6 KXT02765.1 - 1.2 8.9 5.5 4.4 7.1 0.4 2.2 2 0 0 2 2 2 0 YMGG-like Gly-zipper Arginase PF00491.21 KXT02766.1 - 2.5e-92 309.4 0.0 2.9e-92 309.1 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KXT02766.1 - 0.011 16.0 0.3 0.018 15.3 0.3 1.4 1 0 0 1 1 1 0 UPF0489 domain EMC3_TMCO1 PF01956.16 KXT02767.1 - 3e-59 199.6 0.8 4.2e-59 199.1 0.8 1.2 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like DUF2014 PF09427.10 KXT02781.1 - 1.9e-98 329.0 1.3 2.7e-98 328.5 1.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.26 KXT02781.1 - 1.4e-15 57.0 0.5 3.1e-15 55.9 0.5 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Dynamitin PF04912.14 KXT02781.1 - 0.0012 18.2 0.9 0.0021 17.5 0.9 1.2 1 0 0 1 1 1 1 Dynamitin CCDC74_C PF14917.6 KXT02781.1 - 0.027 15.0 2.6 0.033 14.7 0.5 2.3 2 0 0 2 2 2 0 Coiled coil protein 74, C terminal ZapB PF06005.12 KXT02781.1 - 0.06 13.8 0.8 0.38 11.2 1.3 2.0 2 0 0 2 2 2 0 Cell division protein ZapB Prefoldin_2 PF01920.20 KXT02781.1 - 0.16 11.9 2.0 0.33 10.9 2.0 1.4 1 0 0 1 1 1 0 Prefoldin subunit PKcGMP_CC PF16808.5 KXT02781.1 - 0.18 11.7 0.4 0.47 10.4 0.4 1.6 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ATG16 PF08614.11 KXT02781.1 - 0.34 11.1 8.8 0.69 10.1 8.8 1.6 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) PIEZO PF15917.5 KXT02781.1 - 0.68 9.4 3.7 1.2 8.5 3.7 1.3 1 0 0 1 1 1 0 Piezo RtxA PF07634.11 KXT02782.1 - 0.12 13.0 0.0 0.19 12.3 0.0 1.3 1 0 0 1 1 1 0 RtxA repeat AMP-binding PF00501.28 KXT02783.1 - 1e-14 54.0 0.1 1.4e-14 53.5 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme SO_alpha_A3 PF17806.1 KXT02783.1 - 0.11 12.8 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 Sarcosine oxidase A3 domain F-box_4 PF15966.5 KXT02785.1 - 0.036 14.0 0.1 0.17 11.7 0.0 2.2 1 1 1 2 2 2 0 F-box F-box-like PF12937.7 KXT02785.1 - 0.07 13.0 0.6 0.27 11.2 0.2 2.4 2 0 0 2 2 2 0 F-box-like F-box PF00646.33 KXT02785.1 - 0.082 12.8 0.0 0.28 11.1 0.0 1.9 1 0 0 1 1 1 0 F-box domain Glyco_hydro_61 PF03443.14 KXT02786.1 - 0.027 14.4 0.0 0.074 13.0 0.0 1.7 1 1 0 1 1 1 0 Glycosyl hydrolase family 61 F-box-like PF12937.7 KXT02789.1 - 0.00084 19.2 0.0 0.0023 17.8 0.0 1.8 1 0 0 1 1 1 1 F-box-like CwfJ_C_1 PF04677.15 KXT02790.1 - 0.09 12.7 0.3 0.5 10.2 0.1 1.9 1 1 1 2 2 2 0 Protein similar to CwfJ C-terminus 1 CwfJ_C_1 PF04677.15 KXT02791.1 - 0.1 12.5 0.3 0.49 10.3 0.1 2.0 1 1 1 2 2 2 0 Protein similar to CwfJ C-terminus 1 GST_N_3 PF13417.6 KXT02792.1 - 2.9e-17 62.8 0.1 6.3e-17 61.8 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXT02792.1 - 1.4e-12 47.8 0.1 2.8e-12 46.7 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXT02792.1 - 4.7e-09 36.3 0.0 8.2e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXT02792.1 - 8.2e-08 32.2 0.0 1.5e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXT02792.1 - 1.5e-07 31.5 0.0 2.6e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KXT02792.1 - 8.4e-07 29.3 0.5 2.5e-06 27.7 0.1 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 KXT02792.1 - 0.0038 17.9 0.1 0.008 16.9 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain APS_kinase PF01583.20 KXT02793.1 - 1.7e-72 242.5 0.0 2e-72 242.2 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 KXT02793.1 - 4.5e-05 23.6 0.0 7.6e-05 22.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 KXT02793.1 - 0.00014 21.4 0.0 0.00017 21.1 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 KXT02793.1 - 0.00054 20.5 0.0 0.00093 19.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KXT02793.1 - 0.02 14.7 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.20 KXT02793.1 - 0.033 13.3 0.4 0.069 12.3 0.2 1.5 1 1 0 1 1 1 0 G-protein alpha subunit AAA_16 PF13191.6 KXT02793.1 - 0.038 14.4 0.1 0.069 13.5 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 KXT02793.1 - 0.05 14.1 0.0 0.077 13.5 0.0 1.4 1 1 0 1 1 1 0 ABC transporter DUF463 PF04317.12 KXT02793.1 - 0.062 12.2 0.0 0.081 11.8 0.0 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 6PF2K PF01591.18 KXT02793.1 - 0.09 12.1 0.0 0.15 11.3 0.0 1.5 2 0 0 2 2 2 0 6-phosphofructo-2-kinase APS_kinase PF01583.20 KXT02794.1 - 1.7e-72 242.5 0.0 2e-72 242.2 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 KXT02794.1 - 4.5e-05 23.6 0.0 7.6e-05 22.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 KXT02794.1 - 0.00014 21.4 0.0 0.00017 21.1 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 KXT02794.1 - 0.00054 20.5 0.0 0.00093 19.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KXT02794.1 - 0.02 14.7 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.20 KXT02794.1 - 0.033 13.3 0.4 0.069 12.3 0.2 1.5 1 1 0 1 1 1 0 G-protein alpha subunit AAA_16 PF13191.6 KXT02794.1 - 0.038 14.4 0.1 0.069 13.5 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 KXT02794.1 - 0.05 14.1 0.0 0.077 13.5 0.0 1.4 1 1 0 1 1 1 0 ABC transporter DUF463 PF04317.12 KXT02794.1 - 0.062 12.2 0.0 0.081 11.8 0.0 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 6PF2K PF01591.18 KXT02794.1 - 0.09 12.1 0.0 0.15 11.3 0.0 1.5 2 0 0 2 2 2 0 6-phosphofructo-2-kinase HLH PF00010.26 KXT02795.1 - 3.5e-06 26.9 0.0 7e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF5618 PF18498.1 KXT02795.1 - 0.14 12.4 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5618) GTP_EFTU PF00009.27 KXT02796.1 - 4e-55 186.4 0.0 5.9e-55 185.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KXT02796.1 - 2.6e-41 140.4 0.0 5.6e-41 139.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KXT02796.1 - 5.7e-13 49.1 1.8 5.7e-13 49.1 1.8 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KXT02796.1 - 0.00066 19.8 0.1 0.015 15.4 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AA_permease_2 PF13520.6 KXT02797.1 - 2.7e-56 191.2 52.5 3.3e-56 190.9 52.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXT02797.1 - 3.2e-22 78.8 44.0 4.3e-22 78.4 44.0 1.1 1 0 0 1 1 1 1 Amino acid permease A_deamin PF02137.18 KXT02799.1 - 1.6e-25 90.3 0.0 3.2e-25 89.3 0.0 1.5 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain AA_permease PF00324.21 KXT02800.1 - 5.3e-130 434.2 39.5 6e-130 434.0 39.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXT02800.1 - 7.6e-35 120.5 41.9 1e-34 120.1 41.9 1.0 1 0 0 1 1 1 1 Amino acid permease DLH PF01738.18 KXT02801.1 - 1.8e-15 57.1 0.0 2.5e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Trypan_PARP PF05887.11 KXT02802.1 - 0.027 14.4 0.1 0.03 14.3 0.1 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF1959 PF09218.10 KXT02803.1 - 0.05 13.7 0.0 0.076 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1959) UPF1_Zn_bind PF09416.10 KXT02804.1 - 2.6e-71 238.5 2.9 3.1e-71 238.3 1.0 2.0 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 KXT02804.1 - 1.7e-59 200.8 0.0 3.6e-59 199.8 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_11 PF13086.6 KXT02804.1 - 2.4e-53 181.6 4.0 6.1e-30 104.9 0.4 2.4 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 KXT02804.1 - 6.1e-32 109.7 0.0 1.2e-31 108.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 KXT02804.1 - 1.8e-14 53.9 2.3 8.5e-13 48.5 1.6 2.6 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.6 KXT02804.1 - 4.1e-11 43.4 0.2 3.1e-10 40.6 0.2 2.4 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KXT02804.1 - 4.5e-06 26.6 0.8 0.09 12.5 0.0 2.9 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 KXT02804.1 - 8.9e-06 25.8 0.0 1.7e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 KXT02804.1 - 0.0004 20.3 0.0 0.00081 19.3 0.0 1.5 1 0 0 1 1 1 1 Helicase DUF2075 PF09848.9 KXT02804.1 - 0.00051 19.4 0.0 0.039 13.2 0.0 2.7 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.14 KXT02804.1 - 0.0015 17.8 0.1 0.53 9.4 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase AAA_10 PF12846.7 KXT02804.1 - 0.0029 16.6 0.0 0.0044 16.0 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain DEAD PF00270.29 KXT02804.1 - 0.0064 16.3 0.1 0.012 15.3 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase UvrD-helicase PF00580.21 KXT02804.1 - 0.014 14.9 0.0 0.18 11.3 0.0 2.2 1 1 1 2 2 2 0 UvrD/REP helicase N-terminal domain Ribosomal_S13_N PF08069.12 KXT02804.1 - 0.049 13.7 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain AAA_22 PF13401.6 KXT02804.1 - 0.098 12.9 0.0 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KXT02804.1 - 0.13 11.7 0.0 0.38 10.2 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein SRP54 PF00448.22 KXT02804.1 - 0.13 11.9 0.1 0.25 10.9 0.1 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ATPase PF06745.13 KXT02804.1 - 0.15 11.4 0.1 0.45 9.8 0.0 1.7 2 0 0 2 2 2 0 KaiC AAA_5 PF07728.14 KXT02804.1 - 0.17 11.9 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) zf-UBP PF02148.19 KXT02804.1 - 0.66 10.4 6.7 2.1 8.7 6.7 1.9 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein SLS PF14611.6 KXT02806.1 - 2.3e-21 76.6 1.1 2.4e-20 73.3 0.0 2.3 2 0 0 2 2 2 1 Mitochondrial inner-membrane-bound regulator HTH_Tnp_Tc3_2 PF01498.18 KXT02806.1 - 0.05 13.9 0.4 0.34 11.2 0.0 2.5 2 1 1 3 3 3 0 Transposase YolD PF08863.10 KXT02806.1 - 0.095 12.8 0.1 0.29 11.2 0.1 1.8 1 0 0 1 1 1 0 YolD-like protein p450 PF00067.22 KXT02807.1 - 3.3e-49 167.9 0.0 4.9e-49 167.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 ABC_membrane_2 PF06472.15 KXT02808.1 - 1.7e-102 342.4 1.1 2.8e-102 341.8 1.1 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KXT02808.1 - 1.1e-15 58.4 0.0 3.1e-15 56.9 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KXT02808.1 - 0.0001 22.2 0.0 0.00026 20.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KXT02808.1 - 0.0042 17.6 0.0 0.013 16.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KXT02808.1 - 0.011 15.4 0.0 0.033 13.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain RuvB_N PF05496.12 KXT02808.1 - 0.037 13.8 0.0 0.45 10.3 0.0 2.5 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain SMC_N PF02463.19 KXT02808.1 - 0.043 13.3 0.0 0.093 12.2 0.0 1.5 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Mg_chelatase PF01078.21 KXT02808.1 - 0.062 12.7 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_27 PF13514.6 KXT02808.1 - 0.072 12.7 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 KXT02808.1 - 0.094 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_16 PF13191.6 KXT02808.1 - 0.1 13.0 0.3 0.77 10.1 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 KXT02808.1 - 0.11 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Maf1 PF09174.10 KXT02810.1 - 3.7e-58 196.5 0.1 5.2e-58 196.0 0.1 1.2 1 0 0 1 1 1 1 Maf1 regulator Type_III_YscX PF09474.10 KXT02810.1 - 0.063 13.6 0.0 0.51 10.6 0.0 2.1 2 0 0 2 2 2 0 Type III secretion system YscX (type_III_YscX) Clat_adaptor_s PF01217.20 KXT02811.1 - 4.9e-49 165.9 0.2 6.1e-49 165.6 0.2 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PulA_N1 PF17999.1 KXT02811.1 - 0.065 14.0 0.3 0.12 13.1 0.2 1.5 1 1 0 1 1 1 0 Pullulanase N1-terminal domain Maf1 PF09174.10 KXT02812.1 - 3.7e-58 196.5 0.1 5.2e-58 196.0 0.1 1.2 1 0 0 1 1 1 1 Maf1 regulator Type_III_YscX PF09474.10 KXT02812.1 - 0.063 13.6 0.0 0.51 10.6 0.0 2.1 2 0 0 2 2 2 0 Type III secretion system YscX (type_III_YscX) Maf1 PF09174.10 KXT02813.1 - 3.7e-58 196.5 0.1 5.2e-58 196.0 0.1 1.2 1 0 0 1 1 1 1 Maf1 regulator Type_III_YscX PF09474.10 KXT02813.1 - 0.063 13.6 0.0 0.51 10.6 0.0 2.1 2 0 0 2 2 2 0 Type III secretion system YscX (type_III_YscX) Maf1 PF09174.10 KXT02814.1 - 3.7e-58 196.5 0.1 5.2e-58 196.0 0.1 1.2 1 0 0 1 1 1 1 Maf1 regulator Type_III_YscX PF09474.10 KXT02814.1 - 0.063 13.6 0.0 0.51 10.6 0.0 2.1 2 0 0 2 2 2 0 Type III secretion system YscX (type_III_YscX) Clat_adaptor_s PF01217.20 KXT02815.1 - 1.3e-48 164.5 0.3 1.9e-48 164.0 0.3 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Clat_adaptor_s PF01217.20 KXT02816.1 - 1e-48 164.9 0.3 1.5e-48 164.4 0.3 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PulA_N1 PF17999.1 KXT02816.1 - 0.1 13.4 0.0 0.19 12.5 0.0 1.4 1 0 0 1 1 1 0 Pullulanase N1-terminal domain Maf1 PF09174.10 KXT02817.1 - 3.7e-58 196.5 0.1 5.2e-58 196.0 0.1 1.2 1 0 0 1 1 1 1 Maf1 regulator Type_III_YscX PF09474.10 KXT02817.1 - 0.063 13.6 0.0 0.51 10.6 0.0 2.1 2 0 0 2 2 2 0 Type III secretion system YscX (type_III_YscX) DUF1772 PF08592.11 KXT02818.1 - 2.6e-25 89.3 5.0 3.8e-25 88.8 5.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) TMEM237 PF15383.6 KXT02818.1 - 0.22 10.6 0.7 6 5.9 0.1 2.1 2 0 0 2 2 2 0 Transmembrane protein 237 Acyl_transf_3 PF01757.22 KXT02818.1 - 0.45 9.5 3.3 0.59 9.1 3.4 1.2 1 1 0 1 1 1 0 Acyltransferase family Urb2 PF10441.9 KXT02819.1 - 1.1e-43 149.5 0.2 1.1e-43 149.5 0.2 2.8 2 0 0 2 2 2 1 Urb2/Npa2 family SNF5 PF04855.12 KXT02820.1 - 3.3e-80 269.3 0.0 4.5e-80 268.8 0.0 1.2 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.27 KXT02820.1 - 1.7e-05 24.3 2.3 4.2e-05 23.1 2.3 1.7 1 0 0 1 1 1 1 GATA zinc finger Rubredoxin_2 PF18073.1 KXT02820.1 - 2.6 7.8 6.2 3.7 7.4 2.3 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain HSP90 PF00183.18 KXT02822.1 - 1.8e-221 736.5 33.6 2.4e-221 736.1 33.6 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 KXT02822.1 - 4e-15 56.3 0.1 7.2e-15 55.5 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KXT02822.1 - 7.7e-10 38.7 0.1 7.7e-10 38.7 0.1 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.9 KXT02822.1 - 0.038 14.0 0.4 0.12 12.4 0.4 1.8 1 0 0 1 1 1 0 Tumour suppressor protein NLRC4_HD PF17889.1 KXT02822.1 - 0.35 11.2 0.1 0.35 11.2 0.1 3.6 4 0 0 4 4 4 0 NLRC4 helical domain zf-C2H2 PF00096.26 KXT02824.1 - 6.2e-07 29.5 12.8 0.012 16.0 1.9 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXT02824.1 - 0.0023 18.3 11.3 0.5 10.9 1.1 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXT02824.1 - 0.0049 17.6 11.5 0.037 14.9 1.4 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-Di19 PF05605.12 KXT02824.1 - 0.33 11.3 6.5 0.69 10.3 0.6 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Cytochrom_B561 PF03188.16 KXT02826.1 - 1.4e-05 25.3 11.9 1.4e-05 25.3 11.9 1.9 2 1 0 2 2 2 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 KXT02826.1 - 5.7e-05 22.9 8.0 5.7e-05 22.9 8.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) DUF4079 PF13301.6 KXT02826.1 - 0.54 10.4 15.1 3.9 7.6 13.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) RRM_1 PF00076.22 KXT02827.1 - 6.2e-35 118.9 0.2 3.7e-18 65.1 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KXT02827.1 - 0.022 14.8 0.3 1.2 9.3 0.0 2.5 2 0 0 2 2 2 0 Limkain b1 Nup35_RRM PF05172.13 KXT02827.1 - 0.094 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Pup PF05639.11 KXT02827.1 - 5.7 7.9 7.3 2.5 9.1 3.3 2.4 1 1 1 2 2 2 0 Pup-like protein His_Phos_2 PF00328.22 KXT02829.1 - 1.4e-36 126.7 0.0 1.7e-36 126.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RNA_pol_A_bac PF01000.26 KXT02830.1 - 3.3e-27 95.1 0.0 6.2e-27 94.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KXT02830.1 - 1.6e-17 62.7 0.0 2.1e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain TPR_12 PF13424.6 KXT02831.1 - 0.021 15.1 2.0 0.091 13.1 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KXT02831.1 - 0.033 14.2 0.4 29 5.0 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF659 PF04937.15 KXT02831.1 - 0.033 14.1 0.0 0.065 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) TPR_16 PF13432.6 KXT02831.1 - 0.053 14.2 1.9 0.24 12.1 0.9 2.7 3 1 0 3 3 3 0 Tetratricopeptide repeat Methyltransf_16 PF10294.9 KXT02832.1 - 9.2e-15 54.8 0.0 1.4e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 KXT02832.1 - 0.018 15.8 0.0 0.058 14.1 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain TPR_12 PF13424.6 KXT02833.1 - 0.021 15.1 2.0 0.091 13.1 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KXT02833.1 - 0.033 14.2 0.4 29 5.0 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF659 PF04937.15 KXT02833.1 - 0.033 14.1 0.0 0.065 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) TPR_16 PF13432.6 KXT02833.1 - 0.053 14.2 1.9 0.24 12.1 0.9 2.7 3 1 0 3 3 3 0 Tetratricopeptide repeat Brix PF04427.18 KXT02834.1 - 7.8e-32 110.9 0.1 1e-31 110.6 0.1 1.1 1 0 0 1 1 1 1 Brix domain GATA PF00320.27 KXT02835.1 - 3.3e-16 58.6 2.5 8.6e-16 57.3 2.5 1.8 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 KXT02835.1 - 5.5e-12 45.3 1.7 1.1e-11 44.3 1.7 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) PHD PF00628.29 KXT02836.1 - 2.8e-06 27.1 7.8 5.1e-06 26.3 7.8 1.4 1 0 0 1 1 1 1 PHD-finger ING PF12998.7 KXT02836.1 - 0.037 14.6 0.0 0.1 13.2 0.0 1.8 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding zf-HC5HC2H PF13771.6 KXT02836.1 - 0.057 13.7 0.4 0.13 12.5 0.4 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-BED PF02892.15 KXT02836.1 - 0.086 12.9 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 BED zinc finger zf-HC5HC2H_2 PF13832.6 KXT02836.1 - 0.14 12.3 0.3 0.28 11.3 0.3 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain DUF543 PF04418.12 KXT02837.1 - 1e-29 102.3 0.0 1.2e-29 102.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) MmgE_PrpD PF03972.14 KXT02837.1 - 0.21 10.1 0.0 0.37 9.3 0.0 1.4 2 0 0 2 2 2 0 MmgE/PrpD family Aldo_ket_red PF00248.21 KXT02839.1 - 5.5e-10 38.9 0.0 7.3e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 KXT02840.1 - 5.5e-10 38.9 0.0 7.3e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family TPR_1 PF00515.28 KXT02842.1 - 2.6e-22 77.6 3.0 5.8e-08 32.2 0.0 6.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 KXT02842.1 - 1.2e-20 72.9 1.8 4.2e-08 32.7 0.0 4.9 5 0 0 5 5 5 3 TPR repeat TPR_2 PF07719.17 KXT02842.1 - 2e-20 71.2 7.3 3.6e-06 26.7 0.1 6.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 KXT02842.1 - 7.2e-17 60.1 0.5 0.00015 21.7 0.0 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 KXT02842.1 - 1.1e-15 58.0 13.5 1.1e-06 29.2 1.3 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 KXT02842.1 - 2.7e-13 49.5 6.3 4.5e-05 23.9 0.4 5.1 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 KXT02842.1 - 7.1e-12 44.9 0.5 0.27 11.7 0.0 5.5 5 1 0 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 KXT02842.1 - 4.6e-11 43.1 9.3 0.00086 19.8 0.3 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXT02842.1 - 2e-09 36.8 5.3 0.13 12.3 0.0 5.9 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 KXT02842.1 - 9.9e-08 32.0 4.9 0.0022 18.1 0.4 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXT02842.1 - 1e-07 32.2 7.5 0.0002 21.6 0.3 4.3 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_20 PF14561.6 KXT02842.1 - 9.6e-07 29.1 2.8 0.041 14.2 0.1 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 KXT02842.1 - 2.3e-06 27.9 6.2 7.4 7.4 0.0 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KXT02842.1 - 4.5e-06 26.8 1.2 0.0008 19.6 0.1 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 KXT02842.1 - 0.0032 17.5 0.3 11 6.2 0.0 4.6 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain BTAD PF03704.17 KXT02842.1 - 0.0051 17.3 3.0 0.078 13.4 0.2 3.1 2 1 0 2 2 2 1 Bacterial transcriptional activator domain TPR_3 PF07720.12 KXT02842.1 - 0.0096 15.9 0.0 5.1 7.2 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 KXT02842.1 - 0.012 14.9 10.8 0.054 12.7 1.0 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF484 PF04340.12 KXT02842.1 - 0.048 13.4 0.5 3.4 7.3 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function, DUF484 TPR_10 PF13374.6 KXT02842.1 - 1.1 9.2 8.9 10 6.1 1.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat MAS20 PF02064.15 KXT02842.1 - 8.1 6.5 7.9 6 7.0 0.1 3.9 4 1 0 4 4 4 0 MAS20 protein import receptor ATP-synt_DE_N PF02823.16 KXT02843.1 - 8.4e-16 57.6 0.1 1.7e-15 56.7 0.1 1.4 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DUF2339 PF10101.9 KXT02843.1 - 0.00029 19.6 2.1 0.00045 19.0 2.1 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) Cytochrom_B561 PF03188.16 KXT02843.1 - 0.00097 19.3 6.3 0.0018 18.4 6.3 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 Peptidase_U4 PF03419.13 KXT02843.1 - 0.21 10.8 1.1 0.38 10.0 1.1 1.4 1 0 0 1 1 1 0 Sporulation factor SpoIIGA 7TMR-DISM_7TM PF07695.11 KXT02843.1 - 0.46 10.3 10.3 0.035 14.0 2.0 2.1 2 0 0 2 2 2 0 7TM diverse intracellular signalling MatE PF01554.18 KXT02843.1 - 1.7 8.3 7.7 0.052 13.2 1.5 1.6 2 0 0 2 2 2 0 MatE Pkinase PF00069.25 KXT02844.1 - 4e-60 203.4 0.0 5.6e-59 199.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT02844.1 - 2.4e-27 95.9 0.1 1.4e-18 67.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXT02844.1 - 0.0013 18.7 1.7 0.2 11.5 0.1 3.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_C PF00433.24 KXT02844.1 - 0.0066 17.1 0.1 0.023 15.4 0.1 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 KXT02844.1 - 0.013 14.8 0.2 0.052 12.9 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Haspin_kinase PF12330.8 KXT02844.1 - 0.058 12.3 0.0 0.12 11.3 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain IDO PF01231.18 KXT02845.1 - 2.1e-164 547.4 0.0 2.4e-164 547.2 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Granulin PF00396.18 KXT02852.1 - 4.5 7.7 14.4 15 6.0 14.4 2.0 1 1 0 1 1 1 0 Granulin AIM24 PF01987.17 KXT02853.1 - 6.2e-46 156.7 3.2 7.5e-46 156.5 3.2 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 SBD PF17882.1 KXT02853.1 - 0.12 12.2 2.1 3.5 7.5 0.1 2.9 2 1 0 3 3 3 0 OAA-family lectin sugar binding domain Mito_carr PF00153.27 KXT02854.1 - 3.2e-59 196.9 0.4 1.3e-18 66.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF5518 PF17647.1 KXT02854.1 - 1.2 9.3 4.7 22 5.2 0.1 3.6 4 0 0 4 4 4 0 Family of unknown function (DUF5518) zf-C2H2 PF00096.26 KXT02855.1 - 0.062 13.8 7.2 0.32 11.6 0.1 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXT02855.1 - 0.18 12.7 12.3 0.19 12.6 0.2 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger DUF3074 PF11274.8 KXT02856.1 - 1.7e-36 126.0 0.1 2.5e-36 125.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) PhyH PF05721.13 KXT02856.1 - 0.071 13.4 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) AMP-binding PF00501.28 KXT02857.1 - 6.7e-62 209.4 0.0 8.8e-62 209.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXT02857.1 - 3.4e-13 50.4 0.0 7.5e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain NMO PF03060.15 KXT02857.1 - 0.057 12.8 0.2 0.088 12.2 0.2 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase DUF3099 PF11298.8 KXT02857.1 - 5.4 7.2 5.8 9.5 6.4 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3099) Sod_Fe_C PF02777.18 KXT02858.1 - 1.3e-38 131.3 0.2 3.2e-38 130.0 0.2 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KXT02858.1 - 6.3e-30 103.5 1.6 1.1e-29 102.7 1.6 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Arf PF00025.21 KXT02859.1 - 1.6e-73 245.8 0.1 1.9e-73 245.6 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KXT02859.1 - 3.9e-14 52.9 0.0 5.4e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KXT02859.1 - 1.1e-12 47.7 0.0 1.4e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KXT02859.1 - 2.6e-12 46.6 1.4 2.8e-08 33.3 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KXT02859.1 - 3.4e-12 46.3 0.0 3.8e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KXT02859.1 - 9.6e-11 41.5 0.0 1.2e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KXT02859.1 - 0.00023 21.2 0.0 0.00049 20.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KXT02859.1 - 0.021 14.2 0.2 0.04 13.2 0.0 1.5 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Tachylectin PF14517.6 KXT02859.1 - 0.084 12.4 0.0 0.14 11.7 0.0 1.4 1 1 0 1 1 1 0 Tachylectin Thioredoxin PF00085.20 KXT02860.1 - 1.7e-06 28.0 0.1 2e-06 27.7 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Ribosomal_L24e PF01246.20 KXT02862.1 - 9.3e-27 93.1 0.3 9.3e-27 93.1 0.3 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e DUF775 PF05603.12 KXT02862.1 - 0.34 10.4 2.2 0.45 10.0 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Glyco_transf_8 PF01501.20 KXT02863.1 - 2.7e-09 37.0 0.0 0.0013 18.3 0.1 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 8 2OG-FeII_Oxy_2 PF13532.6 KXT02864.1 - 5e-19 69.3 0.0 6.1e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KXT02864.1 - 0.0085 16.6 0.0 0.034 14.6 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily p450 PF00067.22 KXT02865.1 - 1.2e-57 195.7 0.0 1.5e-57 195.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_8 PF13450.6 KXT02866.1 - 1e-06 28.8 0.8 1.3e-06 28.5 0.8 1.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KXT02866.1 - 0.00033 20.1 4.0 0.00038 19.9 4.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KXT02866.1 - 0.00038 19.6 0.9 0.00038 19.6 0.9 1.0 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 KXT02866.1 - 0.00039 19.2 2.5 0.00048 18.9 2.5 1.0 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 KXT02866.1 - 0.0005 19.4 0.4 0.0005 19.4 0.4 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXT02866.1 - 0.00054 20.5 0.3 0.00057 20.4 0.3 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXT02866.1 - 0.0006 19.5 1.5 0.00064 19.4 1.5 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXT02866.1 - 0.0021 17.2 2.4 0.0022 17.1 2.4 1.1 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 KXT02866.1 - 0.025 13.9 0.8 0.025 13.9 0.8 1.1 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 KXT02866.1 - 0.05 12.7 0.2 0.053 12.6 0.2 1.0 1 0 0 1 1 1 0 Lycopene cyclase protein 3HCDH_N PF02737.18 KXT02866.1 - 0.09 12.6 0.7 0.088 12.7 0.7 1.1 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.14 KXT02866.1 - 0.28 10.0 2.5 0.31 9.8 2.5 1.0 1 0 0 1 1 1 0 Tryptophan halogenase MFS_1 PF07690.16 KXT02868.1 - 7.8e-33 113.8 23.4 7.8e-33 113.8 23.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily CcmD PF04995.14 KXT02868.1 - 0.0066 16.5 0.3 0.021 14.9 0.3 1.9 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) VanZ PF04892.12 KXT02868.1 - 0.023 15.4 0.3 0.094 13.4 0.3 2.1 1 0 0 1 1 1 0 VanZ like family Response_reg PF00072.24 KXT02870.1 - 1.1e-21 77.1 1.2 1.4e-14 54.2 0.1 3.3 3 0 0 3 3 3 2 Response regulator receiver domain HATPase_c PF02518.26 KXT02870.1 - 1.1e-19 71.0 0.0 2.4e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KXT02870.1 - 9.9e-09 35.1 0.0 2.1e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 KXT02870.1 - 0.00029 21.1 0.2 0.011 16.0 0.0 3.5 4 1 0 4 4 4 1 PAS fold HATPase_c_3 PF13589.6 KXT02870.1 - 0.016 15.1 0.0 0.042 13.7 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_8 PF13188.7 KXT02870.1 - 0.016 15.2 0.0 0.047 13.7 0.0 1.8 1 0 0 1 1 1 0 PAS domain p450 PF00067.22 KXT02871.1 - 4.6e-61 207.0 0.0 6.2e-61 206.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2570 PF10828.8 KXT02871.1 - 0.12 12.1 0.3 3.6 7.4 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) PI-PLC-X PF00388.19 KXT02872.1 - 5e-09 35.9 0.0 7.3e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain DUF1771 PF08590.10 KXT02873.1 - 8.5e-17 61.3 15.2 8.5e-17 61.3 15.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 KXT02873.1 - 3.6e-11 43.3 1.0 9.3e-11 41.9 0.1 2.0 2 0 0 2 2 2 1 Smr domain CD225 PF04505.12 KXT02873.1 - 0.31 11.2 1.2 0.56 10.4 1.2 1.4 1 0 0 1 1 1 0 Interferon-induced transmembrane protein MFS_1 PF07690.16 KXT02874.1 - 7.1e-23 81.1 64.3 2.8e-15 56.1 35.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4643 PF15485.6 KXT02874.1 - 1.1 9.0 3.0 1.6 8.5 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4643) PHD PF00628.29 KXT02876.1 - 3.4e-09 36.5 10.8 7.5e-09 35.4 10.8 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KXT02876.1 - 0.00053 19.5 4.2 0.0012 18.4 4.2 1.6 1 0 0 1 1 1 1 PHD-finger C1_2 PF03107.16 KXT02876.1 - 0.35 11.2 9.5 0.4 11.1 5.3 2.4 2 0 0 2 2 2 0 C1 domain GCS PF03074.16 KXT02877.1 - 2.5e-174 579.9 0.0 3e-174 579.6 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase p450 PF00067.22 KXT02879.1 - 3e-45 154.8 0.0 7.1e-45 153.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome P450 ACOX PF01756.19 KXT02879.1 - 1e-35 122.9 0.2 3.9e-35 121.0 0.1 2.0 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 KXT02879.1 - 1.8e-23 83.4 0.2 3.8e-23 82.4 0.2 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 KXT02879.1 - 6.3e-10 39.1 0.0 1.6e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KXT02879.1 - 0.00013 22.2 0.1 0.00059 20.1 0.1 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KXT02879.1 - 0.076 13.7 0.0 0.24 12.1 0.0 1.9 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain Sugar_tr PF00083.24 KXT02880.1 - 1.7e-90 304.1 19.3 2.1e-90 303.8 19.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXT02880.1 - 1.2e-32 113.3 23.1 1.2e-32 113.3 23.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXT02880.1 - 0.00047 18.7 1.3 0.00047 18.7 1.3 2.3 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) ECH_1 PF00378.20 KXT02881.1 - 4.1e-18 65.6 0.0 3e-16 59.5 0.0 2.0 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXT02881.1 - 5.4e-08 32.7 0.0 7.7e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ABC_tran PF00005.27 KXT02882.1 - 1.9e-49 167.7 0.2 4.3e-27 95.3 0.0 4.1 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KXT02882.1 - 1.4e-15 57.9 0.0 0.00081 19.3 0.0 4.6 5 0 0 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXT02882.1 - 1.1e-13 51.1 0.0 0.00016 21.2 0.0 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain Chromo PF00385.24 KXT02882.1 - 1.1e-08 34.8 0.4 2.3e-08 33.8 0.4 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_23 PF13476.6 KXT02882.1 - 1.9e-08 35.1 0.1 0.00033 21.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KXT02882.1 - 2.1e-07 30.6 0.3 0.004 16.9 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KXT02882.1 - 2.7e-07 30.7 0.0 0.0045 17.1 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXT02882.1 - 7e-07 29.3 0.0 0.0063 16.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KXT02882.1 - 5.5e-05 23.4 0.0 0.27 11.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KXT02882.1 - 6.1e-05 23.3 0.0 0.0079 16.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain Cnd1 PF12717.7 KXT02882.1 - 0.00011 22.3 0.0 0.021 14.8 0.2 3.0 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 AAA_15 PF13175.6 KXT02882.1 - 0.00029 20.6 0.1 0.34 10.6 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain DUF87 PF01935.17 KXT02882.1 - 0.00039 20.6 0.8 0.17 12.0 0.0 3.4 4 0 0 4 4 2 1 Helicase HerA, central domain RNA_helicase PF00910.22 KXT02882.1 - 0.00041 20.7 0.0 1.9 8.9 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.6 KXT02882.1 - 0.00069 20.2 0.1 0.26 11.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 KXT02882.1 - 0.00069 18.7 0.1 0.37 9.7 0.0 2.5 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_14 PF13173.6 KXT02882.1 - 0.00097 19.2 0.0 0.57 10.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KXT02882.1 - 0.0011 19.2 0.0 2.7 8.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KXT02882.1 - 0.0018 18.0 0.1 0.4 10.4 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA PF00004.29 KXT02882.1 - 0.0019 18.6 0.0 2.9 8.3 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 KXT02882.1 - 0.0037 17.0 0.0 0.59 9.9 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.13 KXT02882.1 - 0.0041 16.3 0.1 0.72 9.0 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 KXT02882.1 - 0.0044 16.8 0.1 0.99 9.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KXT02882.1 - 0.0047 16.8 0.1 2.3 8.1 0.0 2.4 2 0 0 2 2 2 1 NACHT domain HEAT_EZ PF13513.6 KXT02882.1 - 0.0073 16.8 1.6 0.4 11.2 0.1 3.9 4 0 0 4 4 4 1 HEAT-like repeat HEAT_2 PF13646.6 KXT02882.1 - 0.01 16.2 0.8 0.15 12.5 0.1 3.3 3 0 0 3 3 2 0 HEAT repeats Adaptin_N PF01602.20 KXT02882.1 - 0.013 14.1 0.2 0.037 12.6 0.1 1.7 2 0 0 2 2 2 0 Adaptin N terminal region AAA_27 PF13514.6 KXT02882.1 - 0.013 15.1 0.2 5.9 6.4 0.0 2.7 3 0 0 3 3 2 0 AAA domain Dynamin_N PF00350.23 KXT02882.1 - 0.013 15.5 0.0 1.1 9.3 0.0 2.8 2 0 0 2 2 2 0 Dynamin family HEAT PF02985.22 KXT02882.1 - 0.015 15.5 0.0 1.1e+02 3.4 0.0 5.1 4 0 0 4 4 4 0 HEAT repeat AAA_16 PF13191.6 KXT02882.1 - 0.016 15.6 0.0 1.9 8.8 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain Septin PF00735.18 KXT02882.1 - 0.019 14.2 0.0 6.6 5.9 0.0 2.5 2 0 0 2 2 2 0 Septin Roc PF08477.13 KXT02882.1 - 0.032 14.4 0.0 7.6 6.8 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KXT02882.1 - 0.039 13.1 0.3 20 4.2 0.0 3.1 3 0 0 3 3 3 0 G-protein alpha subunit Alginate_lyase2 PF08787.11 KXT02882.1 - 0.05 13.5 0.2 0.12 12.3 0.0 1.7 2 0 0 2 2 1 0 Alginate lyase CLASP_N PF12348.8 KXT02882.1 - 0.051 13.1 0.0 1.3 8.5 0.0 2.4 2 0 0 2 2 2 0 CLASP N terminal DUF3584 PF12128.8 KXT02882.1 - 0.053 11.0 1.0 2.6 5.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) TsaE PF02367.17 KXT02882.1 - 0.059 13.4 0.1 15 5.6 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 KXT02882.1 - 0.067 12.8 0.3 21 4.6 0.0 3.1 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_13 PF13166.6 KXT02882.1 - 0.069 11.8 0.0 6.4 5.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KXT02882.1 - 0.074 13.0 0.0 0.83 9.6 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_7 PF12775.7 KXT02882.1 - 0.082 12.4 0.1 12 5.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_25 PF13481.6 KXT02882.1 - 0.091 12.3 0.0 9.4 5.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 KXT02882.1 - 0.092 12.4 0.3 13 5.4 0.0 3.1 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.22 KXT02882.1 - 0.099 11.8 0.1 7.4 5.7 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain MukB PF04310.12 KXT02882.1 - 0.14 11.9 0.0 22 4.8 0.0 2.4 2 0 0 2 2 2 0 MukB N-terminal SR-25 PF10500.9 KXT02882.1 - 0.31 10.6 5.6 0.34 10.5 3.7 1.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein ABC_tran PF00005.27 KXT02883.1 - 1.9e-49 167.7 0.2 4.3e-27 95.3 0.0 4.1 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KXT02883.1 - 1.4e-15 57.9 0.0 0.00081 19.3 0.0 4.6 5 0 0 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXT02883.1 - 1.1e-13 51.1 0.0 0.00016 21.2 0.0 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain Chromo PF00385.24 KXT02883.1 - 1.1e-08 34.8 0.4 2.3e-08 33.8 0.4 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_23 PF13476.6 KXT02883.1 - 1.9e-08 35.1 0.1 0.00033 21.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KXT02883.1 - 2.1e-07 30.6 0.3 0.004 16.9 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KXT02883.1 - 2.7e-07 30.7 0.0 0.0045 17.1 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXT02883.1 - 7e-07 29.3 0.0 0.0063 16.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KXT02883.1 - 5.5e-05 23.4 0.0 0.27 11.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KXT02883.1 - 6.1e-05 23.3 0.0 0.0079 16.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain Cnd1 PF12717.7 KXT02883.1 - 0.00011 22.3 0.0 0.021 14.8 0.2 3.0 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 AAA_15 PF13175.6 KXT02883.1 - 0.00029 20.6 0.1 0.34 10.6 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain DUF87 PF01935.17 KXT02883.1 - 0.00039 20.6 0.8 0.17 12.0 0.0 3.4 4 0 0 4 4 2 1 Helicase HerA, central domain RNA_helicase PF00910.22 KXT02883.1 - 0.00041 20.7 0.0 1.9 8.9 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.6 KXT02883.1 - 0.00069 20.2 0.1 0.26 11.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 KXT02883.1 - 0.00069 18.7 0.1 0.37 9.7 0.0 2.5 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_14 PF13173.6 KXT02883.1 - 0.00097 19.2 0.0 0.57 10.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KXT02883.1 - 0.0011 19.2 0.0 2.7 8.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KXT02883.1 - 0.0018 18.0 0.1 0.4 10.4 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA PF00004.29 KXT02883.1 - 0.0019 18.6 0.0 2.9 8.3 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 KXT02883.1 - 0.0037 17.0 0.0 0.59 9.9 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.13 KXT02883.1 - 0.0041 16.3 0.1 0.72 9.0 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 KXT02883.1 - 0.0044 16.8 0.1 0.99 9.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KXT02883.1 - 0.0047 16.8 0.1 2.3 8.1 0.0 2.4 2 0 0 2 2 2 1 NACHT domain HEAT_EZ PF13513.6 KXT02883.1 - 0.0073 16.8 1.6 0.4 11.2 0.1 3.9 4 0 0 4 4 4 1 HEAT-like repeat HEAT_2 PF13646.6 KXT02883.1 - 0.01 16.2 0.8 0.15 12.5 0.1 3.3 3 0 0 3 3 2 0 HEAT repeats Adaptin_N PF01602.20 KXT02883.1 - 0.013 14.1 0.2 0.037 12.6 0.1 1.7 2 0 0 2 2 2 0 Adaptin N terminal region AAA_27 PF13514.6 KXT02883.1 - 0.013 15.1 0.2 5.9 6.4 0.0 2.7 3 0 0 3 3 2 0 AAA domain Dynamin_N PF00350.23 KXT02883.1 - 0.013 15.5 0.0 1.1 9.3 0.0 2.8 2 0 0 2 2 2 0 Dynamin family HEAT PF02985.22 KXT02883.1 - 0.015 15.5 0.0 1.1e+02 3.4 0.0 5.1 4 0 0 4 4 4 0 HEAT repeat AAA_16 PF13191.6 KXT02883.1 - 0.016 15.6 0.0 1.9 8.8 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain Septin PF00735.18 KXT02883.1 - 0.019 14.2 0.0 6.6 5.9 0.0 2.5 2 0 0 2 2 2 0 Septin Roc PF08477.13 KXT02883.1 - 0.032 14.4 0.0 7.6 6.8 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KXT02883.1 - 0.039 13.1 0.3 20 4.2 0.0 3.1 3 0 0 3 3 3 0 G-protein alpha subunit Alginate_lyase2 PF08787.11 KXT02883.1 - 0.05 13.5 0.2 0.12 12.3 0.0 1.7 2 0 0 2 2 1 0 Alginate lyase CLASP_N PF12348.8 KXT02883.1 - 0.051 13.1 0.0 1.3 8.5 0.0 2.4 2 0 0 2 2 2 0 CLASP N terminal DUF3584 PF12128.8 KXT02883.1 - 0.053 11.0 1.0 2.6 5.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) TsaE PF02367.17 KXT02883.1 - 0.059 13.4 0.1 15 5.6 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 KXT02883.1 - 0.067 12.8 0.3 21 4.6 0.0 3.1 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_13 PF13166.6 KXT02883.1 - 0.069 11.8 0.0 6.4 5.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KXT02883.1 - 0.074 13.0 0.0 0.83 9.6 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_7 PF12775.7 KXT02883.1 - 0.082 12.4 0.1 12 5.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_25 PF13481.6 KXT02883.1 - 0.091 12.3 0.0 9.4 5.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 KXT02883.1 - 0.092 12.4 0.3 13 5.4 0.0 3.1 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.22 KXT02883.1 - 0.099 11.8 0.1 7.4 5.7 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain MukB PF04310.12 KXT02883.1 - 0.14 11.9 0.0 22 4.8 0.0 2.4 2 0 0 2 2 2 0 MukB N-terminal SR-25 PF10500.9 KXT02883.1 - 0.31 10.6 5.6 0.34 10.5 3.7 1.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein PX PF00787.24 KXT02884.1 - 1.7e-14 53.8 0.0 2.9e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 PX domain ACP_PD PF04336.12 KXT02884.1 - 0.041 14.3 0.2 3.3 8.2 0.0 2.4 2 0 0 2 2 2 0 Acyl carrier protein phosphodiesterase Syntaxin-6_N PF09177.11 KXT02884.1 - 0.22 12.1 0.1 0.22 12.1 0.1 2.6 3 1 0 3 3 3 0 Syntaxin 6, N-terminal PhyH PF05721.13 KXT02886.1 - 1.6e-08 35.0 0.1 4.7e-08 33.6 0.1 1.7 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 KXT02886.1 - 2.5e-05 23.3 0.0 0.011 14.6 0.1 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF1479) Ribonuclease_3 PF00636.26 KXT02887.1 - 2.7e-36 124.4 0.0 3e-18 66.4 0.0 2.9 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KXT02887.1 - 6.7e-25 87.7 0.0 3.7e-12 46.5 0.0 3.7 3 0 0 3 3 3 2 Ribonuclease-III-like Dicer_dimer PF03368.14 KXT02887.1 - 3.5e-20 72.0 0.4 1.4e-19 70.0 0.0 2.1 2 0 0 2 2 2 1 Dicer dimerisation domain DEAD PF00270.29 KXT02887.1 - 6.7e-18 65.1 0.0 1.5e-17 64.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXT02887.1 - 3.7e-15 56.2 0.0 1.2e-14 54.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXT02887.1 - 1.7e-12 47.7 0.0 5.9e-12 45.9 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF3638 PF12340.8 KXT02887.1 - 0.00014 21.2 0.0 0.00025 20.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) dsrm PF00035.26 KXT02887.1 - 0.0046 17.6 0.2 0.012 16.3 0.2 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif Cu_bind_CorA PF18252.1 KXT02887.1 - 0.021 14.5 0.1 0.92 9.1 0.0 2.6 3 0 0 3 3 3 0 Copper(I)-binding protein CorA PMI_typeI PF01238.21 KXT02888.1 - 1.5e-144 481.9 0.0 1.7e-144 481.6 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I tRNA_bind_2 PF13725.6 KXT02888.1 - 0.027 14.2 0.6 0.13 11.9 0.3 1.9 2 0 0 2 2 2 0 Possible tRNA binding domain G-alpha PF00503.20 KXT02889.1 - 1.7e-106 356.4 0.3 1.7e-106 356.4 0.3 1.7 2 0 0 2 2 2 1 G-protein alpha subunit Arf PF00025.21 KXT02889.1 - 6.5e-13 48.5 1.8 1.6e-08 34.2 0.0 2.9 3 0 0 3 3 3 2 ADP-ribosylation factor family SET PF00856.28 KXT02889.1 - 7.8e-11 42.6 0.0 8.9e-10 39.2 0.0 2.4 1 1 0 1 1 1 1 SET domain Gtr1_RagA PF04670.12 KXT02889.1 - 0.00062 19.2 0.5 0.028 13.8 0.1 2.5 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KXT02889.1 - 0.085 13.1 0.1 5.7 7.2 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 KXT02889.1 - 0.1 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family PP2C_C PF07830.13 KXT02889.1 - 5.6 7.5 5.0 30 5.2 1.2 2.8 3 0 0 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain Hexapep PF00132.24 KXT02890.1 - 1.3e-10 40.6 12.1 1.3e-06 27.8 2.0 4.5 4 0 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KXT02890.1 - 2e-05 24.3 8.0 0.00032 20.4 3.0 4.8 4 1 1 5 5 5 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 KXT02890.1 - 0.048 12.6 0.0 0.056 12.4 0.0 1.2 1 0 0 1 1 1 0 L-fucokinase Rotamase_3 PF13616.6 KXT02891.1 - 7.2e-17 62.0 0.0 1.3e-16 61.1 0.0 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 KXT02891.1 - 2.7e-15 57.1 0.0 4.7e-15 56.3 0.0 1.3 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 KXT02891.1 - 3.7e-06 27.8 0.4 4.7e-06 27.5 0.4 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain FA_hydroxylase PF04116.13 KXT02892.1 - 9.3e-23 81.0 11.7 9.3e-23 81.0 11.7 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily FAD_binding_2 PF00890.24 KXT02893.1 - 2.4e-124 415.6 2.0 3e-124 415.3 2.0 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 KXT02893.1 - 2.6e-44 150.3 2.0 4e-44 149.7 2.0 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 KXT02893.1 - 7.2e-05 22.2 0.6 0.041 13.1 0.2 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXT02893.1 - 0.00012 21.4 0.2 0.064 12.5 0.0 2.4 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.22 KXT02893.1 - 0.00014 21.1 0.8 0.13 11.3 1.1 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KXT02893.1 - 0.0044 16.3 0.4 0.0085 15.4 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KXT02893.1 - 0.023 14.3 0.8 0.069 12.7 0.3 1.8 1 1 0 2 2 2 0 FAD dependent oxidoreductase Mab-21 PF03281.14 KXT02893.1 - 0.18 11.1 0.1 0.26 10.6 0.1 1.2 1 0 0 1 1 1 0 Mab-21 protein HAD_2 PF13419.6 KXT02894.1 - 0.00012 22.3 0.0 0.00028 21.0 0.0 1.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KXT02895.1 - 0.00012 22.3 0.0 0.00028 21.0 0.0 1.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KXT02896.1 - 0.00012 22.3 0.0 0.00028 21.0 0.0 1.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase MFS_1 PF07690.16 KXT02897.1 - 6.2e-33 114.2 36.9 6.2e-33 114.2 36.9 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 KXT02897.1 - 0.0037 15.6 5.1 0.0061 14.9 4.3 1.8 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family YrhK PF14145.6 KXT02897.1 - 0.22 11.4 7.6 0.28 11.1 0.6 2.8 2 0 0 2 2 2 0 YrhK-like protein Shisa PF13908.6 KXT02898.1 - 0.00023 21.4 1.0 0.00023 21.4 1.0 2.1 3 0 0 3 3 3 1 Wnt and FGF inhibitory regulator TcfC PF16967.5 KXT02898.1 - 0.069 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 E-set like domain Hira PF07569.11 KXT02900.1 - 4.2e-85 285.0 0.1 9.1e-85 283.9 0.1 1.6 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.32 KXT02900.1 - 4.9e-30 103.1 19.7 2.4e-05 25.0 0.0 8.6 7 1 1 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXT02900.1 - 1.1e-14 54.4 0.0 0.032 14.5 0.0 6.4 5 1 2 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 KXT02900.1 - 1.4e-12 47.1 0.7 2.9e-12 46.1 0.7 1.5 1 0 0 1 1 1 1 HIRA B motif Ge1_WD40 PF16529.5 KXT02900.1 - 2.4e-05 23.5 0.6 0.14 11.1 0.0 4.8 4 1 1 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 KXT02900.1 - 0.0044 15.1 0.1 0.13 10.3 0.0 2.4 3 0 0 3 3 3 1 IKI3 family PD40 PF07676.12 KXT02900.1 - 0.021 14.8 0.1 16 5.6 0.0 3.4 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Anp1 PF03452.14 KXT02901.1 - 5.8e-110 366.8 0.0 6.8e-110 366.6 0.0 1.0 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 KXT02901.1 - 0.072 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 Abhydrolase_3 PF07859.13 KXT02902.1 - 0.0043 16.9 0.0 0.0058 16.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold FPN1 PF06963.12 KXT02903.1 - 1.5e-114 382.9 13.2 2e-114 382.5 13.2 1.2 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Peptidase_C50 PF03568.17 KXT02904.1 - 1.1e-145 485.7 0.0 3e-145 484.3 0.0 1.8 2 0 0 2 2 2 1 Peptidase family C50 Atypical_Card PF18461.1 KXT02904.1 - 0.069 13.4 0.0 9.8 6.5 0.0 2.9 2 0 0 2 2 2 0 Atypical caspase recruitment domain TPR_2 PF07719.17 KXT02904.1 - 5.4 7.4 8.8 11 6.4 0.4 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Glyco_transf_90 PF05686.12 KXT02905.1 - 1.6e-24 86.6 0.9 2.6e-24 85.9 0.9 1.3 1 1 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 KXT02905.1 - 0.00015 22.1 0.0 0.00028 21.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 tRNA-synt_1c_C PF03950.18 KXT02905.1 - 0.0078 16.1 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain zf-C2H2 PF00096.26 KXT02906.1 - 0.051 14.1 19.2 4.1 8.1 0.1 5.4 5 0 0 5 5 5 0 Zinc finger, C2H2 type Sporozoite_P67 PF05642.11 KXT02906.1 - 0.093 10.8 2.9 0.19 9.8 2.9 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen zf-C2H2_4 PF13894.6 KXT02906.1 - 0.42 11.6 17.0 11 7.2 0.1 5.3 4 1 0 4 4 4 0 C2H2-type zinc finger PBP1_TM PF14812.6 KXT02906.1 - 1.4 9.4 5.9 3.8 7.9 5.9 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-H2C2_2 PF13465.6 KXT02906.1 - 7.9 7.1 13.7 1.1 9.8 1.5 3.6 4 0 0 4 4 4 0 Zinc-finger double domain ABC_tran PF00005.27 KXT02907.1 - 1.7e-26 93.4 0.0 3.4e-26 92.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KXT02907.1 - 0.0023 17.8 0.2 0.0046 16.9 0.2 1.4 1 0 0 1 1 1 1 RsgA GTPase RNA_helicase PF00910.22 KXT02907.1 - 0.037 14.4 0.3 8.1 6.9 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_21 PF13304.6 KXT02907.1 - 0.053 13.3 0.0 0.14 11.9 0.0 1.7 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 KXT02907.1 - 0.16 12.0 0.1 0.32 11.1 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase IIGP PF05049.13 KXT02907.1 - 0.19 10.8 0.1 0.3 10.1 0.1 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Scs3p PF10261.9 KXT02908.1 - 8.8e-76 254.7 3.8 1.1e-75 254.4 3.8 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Dynamin_M PF01031.20 KXT02909.1 - 2.4e-19 69.7 2.5 5.8e-18 65.1 0.0 2.3 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 KXT02909.1 - 2.6e-11 43.8 0.3 7.1e-10 39.2 0.0 3.2 2 2 0 2 2 2 1 Dynamin family AAA_16 PF13191.6 KXT02909.1 - 0.001 19.5 1.1 0.047 14.1 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain GED PF02212.18 KXT02909.1 - 0.0024 18.0 0.2 0.025 14.7 0.0 2.8 3 0 0 3 3 3 1 Dynamin GTPase effector domain Roc PF08477.13 KXT02909.1 - 0.0074 16.5 0.0 0.1 12.8 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KXT02909.1 - 0.033 14.3 0.3 1.1 9.4 0.0 3.0 2 1 0 2 2 2 0 50S ribosome-binding GTPase Ras PF00071.22 KXT02909.1 - 0.097 12.3 0.1 0.21 11.1 0.1 1.6 1 0 0 1 1 1 0 Ras family RRM_1 PF00076.22 KXT02910.1 - 6.6e-19 67.5 0.1 1.7e-18 66.2 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXT02910.1 - 0.00032 20.7 0.0 0.0011 19.1 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif DNA_pol_phi PF04931.13 KXT02910.1 - 6.2 4.8 8.7 8.3 4.4 8.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi MFS_1 PF07690.16 KXT02911.1 - 1.6e-37 129.3 48.6 1.6e-37 129.3 48.6 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXT02911.1 - 3.4e-12 46.0 15.2 3.4e-12 46.0 15.2 2.8 2 2 0 2 2 2 1 Sugar (and other) transporter DUF3188 PF11384.8 KXT02911.1 - 7.7 6.3 8.8 23 4.8 0.9 4.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3188) MFS_1 PF07690.16 KXT02912.1 - 4.3e-16 58.8 22.8 4.3e-16 58.8 22.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF5321 PF17254.2 KXT02913.1 - 4.4e-49 166.0 2.7 6.5e-49 165.4 2.7 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5321) DUF3987 PF13148.6 KXT02913.1 - 2.2 7.2 10.7 1.2 8.0 7.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Aldo_ket_red PF00248.21 KXT02915.1 - 2.7e-67 227.1 0.0 3.4e-67 226.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family 5_nucleotid PF05761.14 KXT02915.1 - 0.07 12.0 0.2 0.11 11.4 0.2 1.2 1 0 0 1 1 1 0 5' nucleotidase family AD PF09793.9 KXT02918.1 - 4.7e-06 26.6 0.0 1.2e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain Peptidase_U57 PF05582.12 KXT02918.1 - 0.07 12.4 0.5 0.083 12.1 0.5 1.1 1 0 0 1 1 1 0 YabG peptidase U57 FAD_binding_3 PF01494.19 KXT02919.1 - 8.9e-24 84.4 0.0 4.9e-23 81.9 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXT02919.1 - 9.2e-06 25.8 0.8 2.2e-05 24.6 0.8 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXT02919.1 - 9.8e-05 22.1 0.1 0.00017 21.3 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXT02919.1 - 0.00012 21.5 1.9 0.0086 15.3 0.7 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KXT02919.1 - 0.01 15.1 0.0 4.2 6.5 0.0 2.4 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Thi4 PF01946.17 KXT02919.1 - 0.018 14.3 0.0 0.03 13.6 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 KXT02919.1 - 0.065 12.3 0.2 4.2 6.3 0.2 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 KXT02919.1 - 0.14 11.2 0.2 0.25 10.4 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain DUF2183 PF09949.9 KXT02920.1 - 1.9e-17 63.4 0.0 2.9e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) GOLGA2L5 PF15070.6 KXT02920.1 - 0.011 14.5 0.0 0.011 14.5 0.0 1.0 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 OTCace_N PF02729.21 KXT02920.1 - 0.11 12.5 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain DUF2183 PF09949.9 KXT02921.1 - 1.9e-10 41.0 0.0 3.2e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) DUF2183 PF09949.9 KXT02922.1 - 1.1e-14 54.5 0.0 3.2e-14 53.1 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) AA_permease_2 PF13520.6 KXT02923.1 - 4e-52 177.5 45.8 5.5e-52 177.0 45.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXT02923.1 - 1.5e-19 70.0 42.4 2e-19 69.6 42.4 1.0 1 0 0 1 1 1 1 Amino acid permease TEX29 PF15839.5 KXT02923.1 - 0.068 13.8 2.3 0.17 12.5 2.3 1.6 1 0 0 1 1 1 0 Testis-expressed sequence 29 protein Orai-1 PF07856.12 KXT02923.1 - 0.82 9.3 8.8 0.28 10.9 1.5 2.8 2 0 0 2 2 2 0 Mediator of CRAC channel activity KH_1 PF00013.29 KXT02924.1 - 3.5e-42 142.1 5.4 1.8e-18 66.1 0.3 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KXT02924.1 - 4e-12 45.8 4.3 0.0042 16.9 0.3 3.3 3 0 0 3 3 3 3 KH domain MOEP19 PF16005.5 KXT02924.1 - 9.3e-05 22.4 0.0 0.022 14.8 0.0 2.3 2 0 0 2 2 2 2 KH-like RNA-binding domain KH_4 PF13083.6 KXT02924.1 - 0.00025 20.9 6.5 1.1 9.2 0.0 3.7 4 0 0 4 4 4 2 KH domain KH_5 PF13184.6 KXT02924.1 - 0.0071 16.4 11.7 0.27 11.3 0.2 3.7 4 1 0 4 4 4 2 NusA-like KH domain Pyr_redox_2 PF07992.14 KXT02925.1 - 0.006 15.8 0.0 0.007 15.6 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXT02925.1 - 0.11 12.7 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Ribosomal_L23eN PF03939.13 KXT02925.1 - 0.26 11.5 0.1 0.26 11.5 0.1 1.6 2 0 0 2 2 2 0 Ribosomal protein L23, N-terminal domain DUF1330 PF07045.11 KXT02926.1 - 0.0014 18.9 0.1 1.3 9.5 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF1330) ABM PF03992.16 KXT02926.1 - 0.0018 18.4 0.0 0.0078 16.3 0.0 2.0 2 0 0 2 2 2 1 Antibiotic biosynthesis monooxygenase iPGM_N PF06415.13 KXT02928.1 - 4.3e-75 251.9 0.0 6.8e-75 251.2 0.0 1.3 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 KXT02928.1 - 6e-67 225.6 0.1 6.9e-67 225.4 0.1 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 KXT02928.1 - 2.2e-07 30.6 0.0 8.8e-07 28.6 0.0 1.8 1 1 1 2 2 2 1 Sulfatase Phosphodiest PF01663.22 KXT02928.1 - 2.1e-06 27.6 0.0 3.5e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Alk_phosphatase PF00245.20 KXT02928.1 - 0.0097 14.9 0.2 0.02 13.9 0.1 1.5 2 0 0 2 2 2 1 Alkaline phosphatase DEAD PF00270.29 KXT02929.1 - 2.8e-42 144.4 0.1 4.1e-42 143.9 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXT02929.1 - 6.7e-27 94.0 1.1 2e-26 92.5 0.4 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXT02929.1 - 0.0011 19.0 0.0 0.002 18.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KXT02929.1 - 0.0098 15.3 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit TP_methylase PF00590.20 KXT02930.1 - 5e-22 78.9 0.0 8e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Npun_R1517 PF18068.1 KXT02930.1 - 0.14 12.5 0.0 0.34 11.3 0.0 1.6 1 0 0 1 1 1 0 Npun R1517 MAPEG PF01124.18 KXT02931.1 - 3.2e-09 36.8 2.3 5.1e-09 36.1 2.3 1.3 1 0 0 1 1 1 1 MAPEG family MIB_HERC2 PF06701.13 KXT02932.1 - 0.014 15.6 0.1 0.16 12.3 0.0 2.2 2 0 0 2 2 2 0 Mib_herc2 DUF1182 PF06681.13 KXT02932.1 - 0.04 13.5 3.5 0.069 12.7 3.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1182) tRNA_m1G_MT PF01746.21 KXT02933.1 - 6.5e-27 94.5 0.1 3.4e-20 72.6 0.0 2.2 1 1 1 2 2 2 2 tRNA (Guanine-1)-methyltransferase Ysc84 PF04366.12 KXT02934.1 - 0.0092 15.7 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator Glyco_hydro_18 PF00704.28 KXT02935.1 - 6.2e-17 62.3 0.0 6.9e-12 45.7 0.0 2.8 2 1 0 2 2 2 2 Glycosyl hydrolases family 18 Pentapeptide PF00805.22 KXT02935.1 - 0.00012 21.6 0.3 0.00025 20.6 0.3 1.6 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) SMC_N PF02463.19 KXT02936.1 - 2.1e-26 92.7 0.0 4.7e-26 91.6 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KXT02936.1 - 2.3e-15 57.7 8.1 2.3e-15 57.7 8.1 5.1 2 2 1 3 3 3 1 AAA domain AAA_15 PF13175.6 KXT02936.1 - 3.4e-11 43.5 6.3 3.4e-11 43.5 6.3 3.0 3 1 0 3 3 3 1 AAA ATPase domain AAA_21 PF13304.6 KXT02936.1 - 2e-06 27.8 6.8 0.00082 19.3 0.1 3.7 4 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KXT02936.1 - 0.0015 18.8 0.0 0.0057 16.9 0.0 2.1 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KXT02936.1 - 0.0022 17.7 0.2 0.0077 15.9 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain RCC1 PF00415.18 KXT02937.1 - 3.6e-30 104.3 0.1 2.6e-07 31.2 0.0 6.5 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KXT02937.1 - 6.9e-14 51.2 24.5 5.3e-11 42.0 0.5 6.3 8 0 0 8 8 8 3 Regulator of chromosome condensation (RCC1) repeat Transgly PF00912.22 KXT02937.1 - 0.21 11.0 1.7 0.36 10.3 1.7 1.4 1 0 0 1 1 1 0 Transglycosylase MFS_1 PF07690.16 KXT02938.1 - 2.2e-20 72.9 38.7 1.8e-19 69.9 38.3 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Gar1 PF04410.14 KXT02940.1 - 2.5e-38 131.3 0.0 3e-38 131.0 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Glyco_hydro_32N PF00251.20 KXT02941.1 - 2.7e-37 129.0 3.6 8e-37 127.4 3.6 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KXT02941.1 - 4.3e-26 91.8 0.0 8.8e-26 90.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal DUF4975 PF16346.5 KXT02941.1 - 1.1e-05 25.5 0.0 1.9e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4975) BNR PF02012.20 KXT02941.1 - 0.032 14.2 0.1 0.19 11.8 0.1 2.5 1 0 0 1 1 1 0 BNR/Asp-box repeat Sugar_tr PF00083.24 KXT02942.1 - 1.9e-89 300.6 26.9 2.2e-89 300.4 26.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXT02942.1 - 9.8e-28 97.1 26.1 9.8e-28 97.1 26.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Pam17 PF08566.10 KXT02942.1 - 0.062 13.2 0.2 0.16 11.8 0.2 1.7 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 Pmp3 PF01679.17 KXT02942.1 - 0.15 12.3 2.9 0.21 11.8 0.1 2.8 3 0 0 3 3 3 0 Proteolipid membrane potential modulator Methyltr_RsmB-F PF01189.17 KXT02944.1 - 3e-23 82.5 0.1 4.9e-17 62.2 0.0 2.4 1 1 1 2 2 2 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KXT02944.1 - 0.00011 22.3 0.0 0.00017 21.7 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 KXT02944.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Med9 PF07544.13 KXT02946.1 - 7.4e-17 61.2 6.0 3.1e-16 59.2 6.0 2.0 1 1 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Phage_GP20 PF06810.11 KXT02946.1 - 0.00033 20.5 1.1 0.00051 19.9 1.1 1.3 1 0 0 1 1 1 1 Phage minor structural protein GP20 Fib_alpha PF08702.10 KXT02946.1 - 0.00092 19.4 1.5 0.0016 18.7 1.5 1.4 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family SKA2 PF16740.5 KXT02946.1 - 0.0023 17.7 0.2 0.0046 16.7 0.2 1.5 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 2 Spc29 PF17082.5 KXT02946.1 - 0.0098 15.8 0.7 0.014 15.3 0.7 1.2 1 0 0 1 1 1 1 Spindle Pole Component 29 DUF3450 PF11932.8 KXT02946.1 - 0.012 14.9 6.2 0.082 12.2 4.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) UPF0242 PF06785.11 KXT02946.1 - 0.012 15.7 3.2 0.018 15.2 3.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Formin_GBD_N PF18382.1 KXT02946.1 - 0.015 15.8 0.4 0.027 14.9 0.4 1.4 1 0 0 1 1 1 0 Formin N-terminal GTPase-binding domain DUF16 PF01519.16 KXT02946.1 - 0.015 15.8 1.8 0.026 15.0 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 Efg1 PF10153.9 KXT02946.1 - 0.015 15.6 3.6 0.023 15.0 3.6 1.3 1 0 0 1 1 1 0 rRNA-processing protein Efg1 NPV_P10 PF05531.12 KXT02946.1 - 0.015 15.7 0.9 0.023 15.1 0.2 1.6 2 0 0 2 2 1 0 Nucleopolyhedrovirus P10 protein Acetyltransf_6 PF13480.7 KXT02946.1 - 0.018 15.2 2.6 0.026 14.7 2.6 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF848 PF05852.11 KXT02946.1 - 0.023 14.8 1.0 0.037 14.2 1.0 1.3 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) DUF2721 PF11026.8 KXT02946.1 - 0.025 14.5 1.7 0.033 14.1 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) BLOC1_2 PF10046.9 KXT02946.1 - 0.027 14.8 1.6 0.058 13.7 1.6 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Med21 PF11221.8 KXT02946.1 - 0.031 14.5 6.9 0.041 14.1 6.9 1.3 1 1 0 1 1 1 0 Subunit 21 of Mediator complex AAA_23 PF13476.6 KXT02946.1 - 0.036 14.6 0.7 0.035 14.6 0.7 1.1 1 0 0 1 1 1 0 AAA domain Occludin_ELL PF07303.13 KXT02946.1 - 0.039 14.7 0.7 0.071 13.8 0.7 1.4 1 0 0 1 1 1 0 Occludin homology domain DUF148 PF02520.17 KXT02946.1 - 0.044 13.9 0.5 0.081 13.0 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF148 DUF1664 PF07889.12 KXT02946.1 - 0.052 13.6 0.9 0.08 13.0 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF5082 PF16888.5 KXT02946.1 - 0.057 13.7 2.7 0.089 13.1 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) TMPIT PF07851.13 KXT02946.1 - 0.12 11.6 1.0 0.15 11.3 1.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein ABC_tran_Xtn PF12848.7 KXT02946.1 - 0.15 12.1 5.3 0.52 10.4 5.0 1.9 1 1 1 2 2 2 0 ABC transporter DUF2730 PF10805.8 KXT02946.1 - 0.17 12.0 1.3 0.33 11.1 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) FlaC_arch PF05377.11 KXT02946.1 - 0.32 11.4 2.3 5.1 7.6 2.3 2.2 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) XhlA PF10779.9 KXT02946.1 - 0.54 10.5 4.6 0.89 9.8 4.6 1.3 1 0 0 1 1 1 0 Haemolysin XhlA BST2 PF16716.5 KXT02946.1 - 1.7 9.3 6.6 5.4 7.7 2.2 2.3 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 DUF4140 PF13600.6 KXT02946.1 - 1.8 9.1 7.9 2.2 8.8 1.7 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) MerR-DNA-bind PF09278.11 KXT02946.1 - 1.9 9.1 10.0 1.4e+02 3.1 10.8 2.8 2 1 1 3 3 3 0 MerR, DNA binding SlyX PF04102.12 KXT02946.1 - 2.2 8.9 11.8 0.23 12.1 4.1 2.5 2 1 1 3 3 2 0 SlyX FlxA PF14282.6 KXT02946.1 - 2.6 8.1 8.7 0.28 11.2 4.4 1.5 2 0 0 2 2 1 0 FlxA-like protein DivIC PF04977.15 KXT02946.1 - 4.3 7.2 8.3 1.7e+02 2.0 8.7 2.3 1 1 0 1 1 1 0 Septum formation initiator Pkr1 PF08636.10 KXT02947.1 - 3.3e-31 107.2 3.6 4.4e-31 106.8 3.6 1.1 1 0 0 1 1 1 1 ER protein Pkr1 FAM176 PF14851.6 KXT02947.1 - 0.065 12.9 1.3 0.1 12.3 0.0 1.8 2 0 0 2 2 2 0 FAM176 family PGA2 PF07543.12 KXT02947.1 - 1.9 8.5 8.8 0.21 11.6 3.3 1.8 2 0 0 2 2 2 0 Protein trafficking PGA2 Ribo_biogen_C PF04034.13 KXT02948.1 - 1.8e-51 173.1 0.0 2.7e-51 172.6 0.0 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 KXT02948.1 - 1.2e-09 37.9 0.1 2.2e-09 37.0 0.1 1.5 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Lactamase_B PF00753.27 KXT02949.1 - 4.6e-09 36.6 0.0 1.6e-08 34.8 0.0 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXT02949.1 - 0.0056 16.2 0.0 0.037 13.6 0.0 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain HATPase_c PF02518.26 KXT02950.1 - 1.3e-20 74.0 0.1 1.3e-19 70.8 0.0 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXT02950.1 - 7.5e-20 71.2 0.1 1.7e-19 70.0 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KXT02950.1 - 1.6e-11 44.1 0.0 6e-11 42.2 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Amdase PF17645.1 KXT02952.1 - 2.4e-16 60.0 0.0 3e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 Arylmalonate decarboxylase Asp_Glu_race PF01177.22 KXT02952.1 - 0.098 12.5 0.0 0.22 11.3 0.0 1.6 1 1 0 1 1 1 0 Asp/Glu/Hydantoin racemase EZH2_N PF18601.1 KXT02952.1 - 0.2 12.0 0.0 0.39 11.1 0.0 1.4 1 0 0 1 1 1 0 EZH2 N-terminal domain K_oxygenase PF13434.6 KXT02953.1 - 2.7e-08 33.3 0.0 4.1e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) DSBA PF01323.20 KXT02954.1 - 8.7e-41 139.8 0.0 1.2e-19 70.8 0.0 3.3 3 1 0 3 3 3 2 DSBA-like thioredoxin domain Sua5_yciO_yrdC PF01300.18 KXT02954.1 - 1.9e-07 30.8 0.0 4.5e-07 29.5 0.0 1.7 1 1 0 1 1 1 1 Telomere recombination Thioredoxin_5 PF13743.6 KXT02954.1 - 0.0064 16.2 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_4 PF13462.6 KXT02954.1 - 0.16 12.2 0.0 1.4 9.1 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin LEA_3 PF03242.13 KXT02957.1 - 0.00051 20.7 0.2 0.0011 19.6 0.2 1.5 1 0 0 1 1 1 1 Late embryogenesis abundant protein Asp_Glu_race PF01177.22 KXT02957.1 - 0.053 13.4 0.0 0.08 12.8 0.0 1.2 1 0 0 1 1 1 0 Asp/Glu/Hydantoin racemase Linker_histone PF00538.19 KXT02958.1 - 1.3e-26 92.7 0.1 3.2e-26 91.5 0.1 1.7 1 0 0 1 1 1 1 linker histone H1 and H5 family PIP5K PF01504.18 KXT02959.1 - 5.9e-101 337.3 0.0 9.8e-101 336.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Lipocalin_5 PF13924.6 KXT02960.1 - 2.1e-30 105.4 0.0 2.6e-30 105.1 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Linker_histone PF00538.19 KXT02961.1 - 1.9e-13 50.6 0.1 4.7e-13 49.3 0.1 1.7 1 0 0 1 1 1 1 linker histone H1 and H5 family SRP-alpha_N PF04086.13 KXT02961.1 - 8.2 6.3 20.7 12 5.7 20.7 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal MFS_1 PF07690.16 KXT02962.1 - 4.1e-44 151.0 63.7 4.6e-40 137.6 46.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXT02962.1 - 0.00043 19.3 2.0 0.00043 19.3 2.0 3.3 3 0 0 3 3 3 1 Sugar (and other) transporter Forkhead PF00250.18 KXT02963.1 - 0.021 15.1 0.0 0.041 14.1 0.0 1.5 1 0 0 1 1 1 0 Forkhead domain DUF1363 PF07101.11 KXT02963.1 - 0.069 13.4 0.1 0.3 11.4 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1363) Peptidase_S28 PF05577.12 KXT02964.1 - 2e-43 148.8 0.7 2.6e-43 148.4 0.7 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Hydrolase_4 PF12146.8 KXT02964.1 - 1.7e-08 34.0 0.0 3.2e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KXT02964.1 - 1e-05 25.1 0.2 2.4e-05 23.9 0.1 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Tannase PF07519.11 KXT02964.1 - 0.0075 15.2 0.1 0.011 14.6 0.1 1.2 1 0 0 1 1 1 1 Tannase and feruloyl esterase DUF2920 PF11144.8 KXT02964.1 - 0.097 11.8 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Abhydrolase_1 PF00561.20 KXT02964.1 - 0.28 10.8 2.9 0.64 9.6 2.6 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S28 PF05577.12 KXT02965.1 - 2e-43 148.8 0.7 2.6e-43 148.4 0.7 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Hydrolase_4 PF12146.8 KXT02965.1 - 1.7e-08 34.0 0.0 3.2e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KXT02965.1 - 1e-05 25.1 0.2 2.4e-05 23.9 0.1 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Tannase PF07519.11 KXT02965.1 - 0.0075 15.2 0.1 0.011 14.6 0.1 1.2 1 0 0 1 1 1 1 Tannase and feruloyl esterase DUF2920 PF11144.8 KXT02965.1 - 0.097 11.8 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Abhydrolase_1 PF00561.20 KXT02965.1 - 0.28 10.8 2.9 0.64 9.6 2.6 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S28 PF05577.12 KXT02966.1 - 2e-43 148.8 0.7 2.6e-43 148.4 0.7 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Hydrolase_4 PF12146.8 KXT02966.1 - 1.7e-08 34.0 0.0 3.2e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KXT02966.1 - 1e-05 25.1 0.2 2.4e-05 23.9 0.1 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Tannase PF07519.11 KXT02966.1 - 0.0075 15.2 0.1 0.011 14.6 0.1 1.2 1 0 0 1 1 1 1 Tannase and feruloyl esterase DUF2920 PF11144.8 KXT02966.1 - 0.097 11.8 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Abhydrolase_1 PF00561.20 KXT02966.1 - 0.28 10.8 2.9 0.64 9.6 2.6 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S28 PF05577.12 KXT02968.1 - 2e-43 148.8 0.7 2.6e-43 148.4 0.7 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Hydrolase_4 PF12146.8 KXT02968.1 - 1.7e-08 34.0 0.0 3.2e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KXT02968.1 - 1e-05 25.1 0.2 2.4e-05 23.9 0.1 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Tannase PF07519.11 KXT02968.1 - 0.0075 15.2 0.1 0.011 14.6 0.1 1.2 1 0 0 1 1 1 1 Tannase and feruloyl esterase DUF2920 PF11144.8 KXT02968.1 - 0.097 11.8 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Abhydrolase_1 PF00561.20 KXT02968.1 - 0.28 10.8 2.9 0.64 9.6 2.6 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold Methyltransf_15 PF09445.10 KXT02969.1 - 2.2e-50 170.4 0.0 2.9e-50 170.1 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 KXT02969.1 - 3.1e-06 26.9 0.0 4.8e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 UPF0020 PF01170.18 KXT02969.1 - 1.1e-05 25.2 0.0 1.6e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Met_10 PF02475.16 KXT02969.1 - 0.00021 21.1 0.0 0.00031 20.5 0.0 1.4 1 1 0 1 1 1 1 Met-10+ like-protein YqzE PF14038.6 KXT02969.1 - 0.0064 16.5 0.4 0.059 13.4 0.1 2.2 2 0 0 2 2 2 1 YqzE-like protein Methyltransf_5 PF01795.19 KXT02969.1 - 0.039 13.5 0.0 0.058 12.9 0.0 1.2 1 0 0 1 1 1 0 MraW methylase family Methyltransf_3 PF01596.17 KXT02969.1 - 0.04 13.1 0.2 0.06 12.5 0.2 1.2 1 0 0 1 1 1 0 O-methyltransferase MTS PF05175.14 KXT02969.1 - 0.053 13.1 0.0 0.076 12.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain N6_Mtase PF02384.16 KXT02969.1 - 0.071 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase Methyltransf_25 PF13649.6 KXT02969.1 - 0.091 13.5 0.0 0.18 12.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 KXT02969.1 - 0.15 12.0 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain FMO-like PF00743.19 KXT02971.1 - 2e-24 85.9 0.0 2.1e-13 49.5 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXT02971.1 - 1.7e-12 47.3 0.5 3e-07 30.0 0.2 3.4 3 1 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXT02971.1 - 4.8e-10 39.2 0.0 2.5e-08 33.5 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXT02971.1 - 1.7e-07 31.4 0.1 4.4e-06 26.8 0.2 3.1 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KXT02971.1 - 2.3e-07 30.9 0.0 5.2e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KXT02971.1 - 3.5e-07 29.7 0.2 0.00039 19.7 0.0 3.0 3 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KXT02971.1 - 6.3e-05 22.7 0.0 0.0094 15.6 0.0 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXT02971.1 - 0.00035 19.9 0.0 0.087 12.1 0.0 2.2 2 0 0 2 2 2 2 Thi4 family Pyr_redox PF00070.27 KXT02971.1 - 0.0025 18.4 0.1 0.089 13.4 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXT02971.1 - 0.038 12.7 0.1 0.11 11.2 0.3 1.6 2 0 0 2 2 2 0 HI0933-like protein Shikimate_DH PF01488.20 KXT02971.1 - 0.067 13.3 0.0 3.3 7.8 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Glu_dehyd_C PF16912.5 KXT02971.1 - 0.14 11.6 0.0 1.6 8.1 0.0 2.2 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus Ldh_1_N PF00056.23 KXT02971.1 - 0.18 11.9 0.0 0.45 10.6 0.0 1.7 2 0 0 2 2 1 0 lactate/malate dehydrogenase, NAD binding domain ABC2_membrane PF01061.24 KXT02972.1 - 8e-85 283.5 60.9 1.6e-44 151.9 19.0 3.1 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.27 KXT02972.1 - 4.3e-37 127.7 0.0 1.4e-17 64.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KXT02972.1 - 9.5e-31 105.6 11.3 1.2e-27 95.6 0.1 3.5 4 0 0 4 4 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KXT02972.1 - 2.7e-17 63.2 0.5 9.9e-17 61.3 0.5 2.1 1 1 0 1 1 1 1 ABC-transporter N-terminal AAA_25 PF13481.6 KXT02972.1 - 7.7e-06 25.6 0.0 0.00029 20.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KXT02972.1 - 0.00013 21.9 0.1 0.0042 17.0 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase ABC2_membrane_3 PF12698.7 KXT02972.1 - 0.00018 20.7 14.1 0.00018 20.7 14.1 3.4 3 2 0 3 3 3 1 ABC-2 family transporter protein AAA_16 PF13191.6 KXT02972.1 - 0.00021 21.7 0.1 0.0082 16.5 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KXT02972.1 - 0.00059 19.5 1.9 0.02 14.6 0.3 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 KXT02972.1 - 0.00082 19.9 0.1 0.01 16.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KXT02972.1 - 0.0032 17.6 0.1 0.049 13.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KXT02972.1 - 0.0087 15.9 0.2 1.8 8.3 0.1 2.8 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 KXT02972.1 - 0.009 15.7 0.2 1.9 8.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KXT02972.1 - 0.014 15.1 0.1 1.6 8.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 KXT02972.1 - 0.017 14.6 0.0 0.19 11.2 0.0 2.5 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KXT02972.1 - 0.041 14.1 0.9 1.6 9.0 0.2 2.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KXT02972.1 - 0.072 13.0 1.6 3.1 7.7 0.3 2.5 2 0 0 2 2 2 0 NACHT domain Ploopntkinase3 PF18751.1 KXT02972.1 - 0.094 12.6 0.2 1.5 8.7 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 MMR_HSR1 PF01926.23 KXT02972.1 - 0.15 12.1 0.4 21 5.3 0.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase cobW PF02492.19 KXT02972.1 - 0.39 10.3 2.1 1.4 8.5 0.2 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 KXT02972.1 - 0.55 10.5 3.6 0.27 11.5 0.5 2.0 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KXT02972.1 - 0.6 10.6 0.0 0.6 10.6 0.0 2.5 3 0 0 3 3 1 0 AAA domain MFS_1 PF07690.16 KXT02973.1 - 3.8e-37 128.0 41.7 5.2e-32 111.1 27.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXT02973.1 - 1.1e-12 47.6 25.5 9.9e-12 44.4 25.5 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 KXT02973.1 - 0.0027 16.1 0.2 0.011 14.0 0.1 1.9 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Acetyltransf_2 PF00797.17 KXT02974.1 - 4.5e-30 105.2 0.1 1e-29 104.1 0.1 1.6 1 1 0 1 1 1 1 N-acetyltransferase Esterase PF00756.20 KXT02975.1 - 1.2e-08 34.9 0.0 4.7e-08 33.0 0.0 2.1 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 KXT02975.1 - 0.0034 16.9 0.0 0.47 9.9 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family adh_short_C2 PF13561.6 KXT02976.1 - 1.8e-34 119.3 0.1 3e-34 118.6 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXT02976.1 - 1.1e-33 116.3 0.1 1.7e-33 115.7 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXT02976.1 - 0.00022 21.2 0.1 0.0014 18.5 0.0 2.1 2 0 0 2 2 2 1 KR domain DTHCT PF08070.11 KXT02977.1 - 0.019 15.7 4.5 0.029 15.1 4.5 1.3 1 0 0 1 1 1 0 DTHCT (NUC029) region Presenilin PF01080.17 KXT02977.1 - 0.084 11.6 1.0 0.093 11.5 1.0 1.0 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 KXT02977.1 - 0.18 11.6 3.0 0.21 11.4 3.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DTHCT PF08070.11 KXT02978.1 - 0.019 15.7 4.5 0.029 15.1 4.5 1.3 1 0 0 1 1 1 0 DTHCT (NUC029) region Presenilin PF01080.17 KXT02978.1 - 0.084 11.6 1.0 0.093 11.5 1.0 1.0 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 KXT02978.1 - 0.18 11.6 3.0 0.21 11.4 3.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 LSM PF01423.22 KXT02979.1 - 4.4e-16 58.3 0.1 5.6e-16 58.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KXT02979.1 - 0.013 15.6 0.0 0.02 15.0 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain DUF2642 PF10842.8 KXT02979.1 - 0.074 12.9 0.1 4.7 7.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2642) Oxidored_molyb PF00174.19 KXT02980.1 - 8.6e-53 178.5 0.0 1.5e-52 177.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KXT02980.1 - 8.4e-31 106.8 0.0 1.9e-30 105.7 0.0 1.6 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 KXT02980.1 - 5.6e-11 42.4 0.0 1e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain BNR PF02012.20 KXT02980.1 - 0.78 10.0 3.6 0.38 10.9 0.2 2.5 2 0 0 2 2 2 0 BNR/Asp-box repeat AAA PF00004.29 KXT02981.1 - 3.9e-45 153.5 0.5 1.4e-44 151.7 0.0 2.2 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KXT02981.1 - 3.9e-10 39.5 0.1 2.5e-09 36.9 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 KXT02981.1 - 7.1e-09 35.8 0.5 2.8e-08 33.9 0.1 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KXT02981.1 - 5.7e-08 33.1 0.0 1.3e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KXT02981.1 - 1.9e-07 31.7 0.7 4.2e-05 24.0 0.0 2.9 2 2 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 KXT02981.1 - 2.9e-06 26.6 0.2 7e-06 25.4 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 KXT02981.1 - 3.3e-05 24.2 1.3 0.0081 16.4 0.1 2.8 1 1 0 2 2 2 1 AAA domain AAA_lid_3 PF17862.1 KXT02981.1 - 0.00024 20.9 0.0 0.00059 19.6 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KXT02981.1 - 0.00038 20.3 0.0 0.0011 18.8 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 KXT02981.1 - 0.00091 19.5 0.0 0.002 18.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXT02981.1 - 0.00098 19.7 0.0 0.0026 18.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 KXT02981.1 - 0.0012 18.1 0.0 0.0023 17.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_7 PF12775.7 KXT02981.1 - 0.0012 18.4 0.1 0.0072 15.9 0.1 2.0 1 1 0 1 1 1 1 P-loop containing dynein motor region RNA_helicase PF00910.22 KXT02981.1 - 0.0013 19.1 0.0 0.0031 17.9 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 KXT02981.1 - 0.0014 18.7 0.2 0.0087 16.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KXT02981.1 - 0.0017 18.1 0.0 0.0041 16.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 KXT02981.1 - 0.0025 17.7 0.0 0.012 15.5 0.0 2.1 2 0 0 2 2 2 1 NTPase NACHT PF05729.12 KXT02981.1 - 0.0046 16.9 0.2 0.11 12.4 0.0 2.9 3 0 0 3 3 3 1 NACHT domain AAA_3 PF07726.11 KXT02981.1 - 0.006 16.4 0.0 0.02 14.8 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KXT02981.1 - 0.0066 16.4 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 KXT02981.1 - 0.0081 15.6 0.0 0.019 14.3 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KXT02981.1 - 0.0082 16.3 0.0 0.02 15.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 KXT02981.1 - 0.01 15.3 0.0 0.55 9.6 0.0 2.4 2 0 0 2 2 2 0 Bacterial TniB protein IstB_IS21 PF01695.17 KXT02981.1 - 0.012 15.4 0.1 0.039 13.7 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_24 PF13479.6 KXT02981.1 - 0.02 14.6 0.2 0.051 13.3 0.2 1.8 1 1 0 1 1 1 0 AAA domain DUF3450 PF11932.8 KXT02981.1 - 0.021 14.1 4.3 0.043 13.1 4.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) AAA_11 PF13086.6 KXT02981.1 - 0.025 14.3 0.3 0.14 12.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KXT02981.1 - 0.031 13.6 1.1 0.52 9.6 0.0 2.7 3 0 0 3 3 3 0 KaiC ATPase_2 PF01637.18 KXT02981.1 - 0.038 13.9 1.3 0.23 11.4 0.1 2.6 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 KXT02981.1 - 0.048 14.2 1.4 5.9 7.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 KXT02981.1 - 0.065 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein Sigma54_activat PF00158.26 KXT02981.1 - 0.09 12.5 0.1 1.4 8.6 0.0 2.4 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.6 KXT02981.1 - 0.11 12.9 0.4 0.41 11.0 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KXT02981.1 - 0.11 12.0 1.9 0.23 11.0 0.2 2.3 2 1 1 3 3 3 0 AAA domain AAA_29 PF13555.6 KXT02981.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain CHD5 PF04420.14 KXT02981.1 - 0.54 10.1 2.8 1.8 8.4 2.8 1.9 1 1 0 1 1 1 0 CHD5-like protein Pkinase PF00069.25 KXT02982.1 - 1.6e-71 240.8 0.0 2e-71 240.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT02982.1 - 4.8e-29 101.4 0.0 6.3e-29 101.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXT02982.1 - 1.4e-07 31.1 0.0 2.2e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXT02982.1 - 0.00012 21.0 0.1 0.00025 20.0 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KXT02982.1 - 0.00035 20.6 0.4 0.00068 19.6 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KXT02982.1 - 0.00046 19.6 0.1 0.00095 18.6 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RQC PF09382.10 KXT02983.1 - 2.8e-22 78.7 0.0 5.7e-22 77.6 0.0 1.6 1 0 0 1 1 1 1 RQC domain DEAD PF00270.29 KXT02983.1 - 1.5e-21 76.9 0.0 3.9e-21 75.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 KXT02983.1 - 1.8e-19 70.2 2.1 8.7e-19 68.0 2.1 2.3 1 0 0 1 1 1 1 RecQ zinc-binding Helicase_C PF00271.31 KXT02983.1 - 4.9e-17 62.3 0.0 2.9e-14 53.3 0.1 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain HRDC PF00570.23 KXT02983.1 - 0.007 16.3 0.0 0.025 14.6 0.0 2.0 1 0 0 1 1 1 1 HRDC domain Rhomboid PF01694.22 KXT02984.1 - 3.3e-19 69.3 6.2 7e-19 68.3 5.9 1.6 2 0 0 2 2 2 1 Rhomboid family DUF417 PF04224.12 KXT02984.1 - 0.059 12.9 0.0 0.35 10.4 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function, DUF417 MR_MLE_C PF13378.6 KXT02989.1 - 5.7e-43 147.0 0.0 7.6e-43 146.6 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KXT02989.1 - 8.3e-10 38.9 0.0 1.4e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain RPS31 PF17067.5 KXT02990.1 - 0.057 13.6 1.7 1.3 9.2 0.1 2.3 2 0 0 2 2 2 0 Ribosomal protein S31e CMD PF02627.20 KXT02992.1 - 2.2e-15 56.5 0.1 1.8e-07 31.1 0.0 2.3 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family CMD PF02627.20 KXT02993.1 - 2.2e-15 56.5 0.1 1.8e-07 31.1 0.0 2.3 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family FAD_binding_3 PF01494.19 KXT02994.1 - 4.7e-46 157.6 0.0 5.7e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXT02994.1 - 2e-05 24.7 0.1 4.8e-05 23.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXT02994.1 - 3.5e-05 23.1 0.0 5.4e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KXT02994.1 - 0.0002 20.2 0.0 0.00031 19.6 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 KXT02994.1 - 0.00022 20.6 0.0 0.00034 19.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXT02994.1 - 0.00049 20.6 0.0 0.0014 19.2 0.0 1.7 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXT02994.1 - 0.0013 18.4 0.0 0.003 17.2 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXT02994.1 - 0.0016 17.7 0.1 0.0026 17.0 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KXT02994.1 - 0.0051 16.1 0.0 0.018 14.3 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXT02994.1 - 0.0058 15.7 0.0 0.0088 15.1 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_7 PF13241.6 KXT02994.1 - 0.037 14.5 0.0 0.088 13.3 0.0 1.7 2 0 0 2 2 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 KXT02994.1 - 0.038 14.1 0.0 0.063 13.3 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 KXT02994.1 - 0.056 13.4 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 KXT02994.1 - 0.14 11.4 0.1 0.24 10.7 0.1 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KXT02994.1 - 0.14 10.9 0.2 0.24 10.2 0.2 1.3 1 0 0 1 1 1 0 Tryptophan halogenase TrkA_N PF02254.18 KXT02994.1 - 0.15 12.3 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain GIDA PF01134.22 KXT02994.1 - 0.27 10.3 0.0 0.43 9.6 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pkinase PF00069.25 KXT02995.1 - 7.1e-67 225.6 0.0 9.4e-67 225.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT02995.1 - 3.7e-39 134.6 0.0 5.1e-39 134.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXT02995.1 - 1.9e-05 23.6 0.0 3.1e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KXT02995.1 - 0.0021 17.5 0.0 0.0034 16.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXT02995.1 - 0.047 13.6 0.0 0.08 12.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 KXT02995.1 - 0.059 13.0 0.0 0.096 12.3 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.11 KXT02995.1 - 0.086 11.9 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 KXT02995.1 - 0.094 11.6 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain zf_CCCH_4 PF18345.1 KXT02996.1 - 2.1e-05 24.4 5.6 4e-05 23.5 5.6 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KXT02996.1 - 3.6e-05 23.6 3.1 6.4e-05 22.8 3.1 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KXT02996.1 - 0.012 16.3 1.1 0.012 16.3 1.1 2.2 2 0 0 2 2 2 0 Torus domain zf-CCCH_4 PF18044.1 KXT02996.1 - 0.014 15.2 1.9 0.023 14.5 1.9 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger Glyco_hydro_79C PF16862.5 KXT02997.1 - 3.1e-23 82.6 0.9 8e-23 81.3 0.3 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain Alpha-amylase PF00128.24 KXT02998.1 - 1.3e-51 176.1 0.1 2.1e-51 175.5 0.1 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 KXT02998.1 - 2.8e-24 85.2 0.1 6.2e-24 84.1 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) RecQ_Zn_bind PF16124.5 KXT02998.1 - 0.15 12.8 0.0 0.36 11.6 0.0 1.6 1 0 0 1 1 1 0 RecQ zinc-binding Syntaxin-18_N PF10496.9 KXT02999.1 - 0.23 11.7 4.5 0.11 12.8 1.2 2.3 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus RNase_PH PF01138.21 KXT03000.1 - 5.5e-33 114.3 0.1 8.3e-33 113.7 0.1 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KXT03000.1 - 0.0061 16.6 0.1 0.011 15.8 0.1 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 RRN3 PF05327.11 KXT03000.1 - 0.18 10.3 0.0 0.24 9.9 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Na_trans_assoc PF06512.13 KXT03003.1 - 3.9 7.7 41.4 1.8e+04 -4.8 40.9 3.4 1 1 0 1 1 1 0 Sodium ion transport-associated PET117 PF15786.5 KXT03004.1 - 2.5e-23 82.1 2.2 3.2e-23 81.8 2.2 1.1 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial RPA_interact_M PF14767.6 KXT03004.1 - 0.037 14.6 2.6 0.047 14.2 2.6 1.3 1 0 0 1 1 1 0 Replication protein A interacting middle Pmp3 PF01679.17 KXT03005.1 - 7e-14 51.8 7.7 9.7e-14 51.3 7.7 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator HNH_repeat PF18780.1 KXT03005.1 - 0.071 12.9 1.3 0.084 12.7 0.0 1.8 2 0 0 2 2 2 0 Homing endonuclease repeat MUG113 PF13455.6 KXT03005.1 - 0.12 13.1 0.0 0.21 12.3 0.0 1.5 1 0 0 1 1 1 0 Meiotically up-regulated gene 113 FTHFS PF01268.19 KXT03006.1 - 4.4e-252 837.2 2.1 6.5e-252 836.7 2.1 1.3 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 KXT03006.1 - 1.9e-66 222.3 1.6 4.6e-66 221.1 1.6 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KXT03006.1 - 2.4e-38 131.0 1.8 6.4e-38 129.6 1.8 1.8 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain SH2_2 PF14633.6 KXT03007.1 - 4.3e-84 281.3 0.3 4.3e-84 281.3 0.3 2.3 2 0 0 2 2 2 1 SH2 domain HHH_7 PF14635.6 KXT03007.1 - 2.4e-32 111.4 0.0 6.2e-32 110.0 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 KXT03007.1 - 4.3e-30 104.5 0.1 1.4e-29 102.8 0.0 2.0 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 HTH_44 PF14641.6 KXT03007.1 - 1.3e-27 96.5 1.0 5e-27 94.6 1.0 2.1 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.6 KXT03007.1 - 1.2e-18 67.4 27.5 1.2e-18 67.4 27.5 4.9 5 0 0 5 5 5 1 Acidic N-terminal SPT6 HHH_9 PF17674.1 KXT03007.1 - 9e-06 26.5 2.8 9e-06 26.5 2.8 4.0 3 1 0 3 3 3 1 HHH domain HHH_3 PF12836.7 KXT03007.1 - 0.00019 21.6 0.1 0.00073 19.7 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif SH2 PF00017.24 KXT03007.1 - 0.0012 18.8 0.0 0.0037 17.3 0.0 1.8 1 0 0 1 1 1 1 SH2 domain LNS2 PF08235.13 KXT03008.1 - 6.9e-90 300.5 0.0 1.3e-89 299.5 0.0 1.5 1 1 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 KXT03008.1 - 4.8e-42 142.1 0.0 9.5e-42 141.1 0.0 1.5 1 0 0 1 1 1 1 lipin, N-terminal conserved region DMPK_coil PF08826.10 KXT03008.1 - 0.21 11.7 0.7 0.48 10.6 0.7 1.5 1 0 0 1 1 1 0 DMPK coiled coil domain like NAD_binding_1 PF00175.21 KXT03009.1 - 6.2e-12 46.1 0.0 1.2e-11 45.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.22 KXT03009.1 - 1.5e-09 38.4 0.1 3.8e-09 37.1 0.0 1.7 2 0 0 2 2 2 1 Globin FAD_binding_6 PF00970.24 KXT03009.1 - 2e-05 24.9 0.0 4.2e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KXT03009.1 - 2.4e-05 24.5 0.0 0.00036 20.7 0.0 2.5 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Protoglobin PF11563.8 KXT03009.1 - 4.8e-05 23.3 0.0 7.9e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Protoglobin MFS_1 PF07690.16 KXT03010.1 - 8.4e-54 182.8 42.9 6.1e-42 143.8 22.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXT03010.1 - 2.6e-05 23.0 31.3 0.041 12.4 8.9 3.3 2 2 0 2 2 2 2 MFS/sugar transport protein MFS_3 PF05977.13 KXT03010.1 - 0.0029 16.1 6.4 0.0029 16.1 6.4 2.5 2 1 0 2 2 2 1 Transmembrane secretion effector OATP PF03137.20 KXT03010.1 - 0.019 13.3 2.8 0.26 9.5 1.3 2.8 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family PTR2 PF00854.21 KXT03010.1 - 0.25 10.1 5.2 0.04 12.7 0.8 1.9 2 1 0 2 2 2 0 POT family DUF5337 PF17272.2 KXT03010.1 - 0.53 10.2 3.0 0.48 10.3 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5337) MFS_1_like PF12832.7 KXT03010.1 - 6 5.6 13.0 1.4 7.7 4.4 3.3 1 1 2 3 3 3 0 MFS_1 like family Lipoxygenase PF00305.19 KXT03011.1 - 7.4e-28 97.4 0.1 7.7e-28 97.3 0.1 1.1 1 0 0 1 1 1 1 Lipoxygenase V-ATPase_G PF03179.15 KXT03012.1 - 6.4e-34 116.6 17.0 7.3e-34 116.5 17.0 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF3450 PF11932.8 KXT03012.1 - 0.015 14.6 11.1 0.017 14.4 11.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ATP-synt_B PF00430.18 KXT03012.1 - 0.028 14.5 12.2 0.028 14.5 12.2 2.1 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) DUF2203 PF09969.9 KXT03012.1 - 0.081 13.6 5.7 0.1 13.3 5.7 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) V-ATPase_G_2 PF16999.5 KXT03012.1 - 0.093 13.1 14.3 0.14 12.6 14.3 1.3 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit OmpH PF03938.14 KXT03012.1 - 0.096 13.0 16.9 0.12 12.7 16.9 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) RRF PF01765.19 KXT03012.1 - 0.15 12.0 12.2 0.2 11.6 12.2 1.4 1 0 0 1 1 1 0 Ribosome recycling factor PIN_8 PF18476.1 KXT03012.1 - 0.15 11.9 7.3 0.17 11.7 7.3 1.0 1 0 0 1 1 1 0 PIN like domain RabGAP-TBC PF00566.18 KXT03012.1 - 0.24 11.0 2.4 0.27 10.9 2.4 1.1 1 0 0 1 1 1 0 Rab-GTPase-TBC domain ATP11 PF06644.11 KXT03012.1 - 0.26 11.0 12.0 0.33 10.7 12.0 1.0 1 0 0 1 1 1 0 ATP11 protein DUF4375 PF14300.6 KXT03012.1 - 0.27 11.5 7.0 0.8 10.0 6.6 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4375) DUF3552 PF12072.8 KXT03012.1 - 0.31 10.4 21.5 0.03 13.7 12.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) SAPS PF04499.15 KXT03012.1 - 0.6 8.8 6.7 0.61 8.8 6.7 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SMBP PF16785.5 KXT03012.1 - 1.3 9.2 6.6 1.7 8.9 6.6 1.2 1 0 0 1 1 1 0 Small metal-binding protein DUF3987 PF13148.6 KXT03012.1 - 1.7 7.6 8.3 1.8 7.5 8.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Borrelia_P83 PF05262.11 KXT03012.1 - 2.2 6.6 15.2 2.5 6.5 15.2 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Atg14 PF10186.9 KXT03012.1 - 3.7 6.6 9.5 3.9 6.5 9.5 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF883 PF05957.13 KXT03012.1 - 4 8.1 10.0 76 4.0 10.2 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) TMPIT PF07851.13 KXT03012.1 - 4.6 6.4 9.1 5 6.3 9.1 1.0 1 0 0 1 1 1 0 TMPIT-like protein RNA_pol_Rpb2_6 PF00562.28 KXT03015.1 - 5.1e-125 417.6 0.1 7.7e-125 417.0 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KXT03015.1 - 1.2e-55 188.2 0.1 2e-55 187.4 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 KXT03015.1 - 5e-45 153.5 0.6 1.2e-43 149.0 0.2 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KXT03015.1 - 8.4e-32 109.4 0.1 2e-31 108.2 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 KXT03015.1 - 1.1e-25 89.6 0.1 2.4e-25 88.5 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 KXT03015.1 - 5.9e-24 84.1 0.5 1.5e-23 82.8 0.5 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 KXT03015.1 - 8.5e-22 77.5 0.3 3e-21 75.7 0.3 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RRM_1 PF00076.22 KXT03017.1 - 6.1e-46 154.1 0.0 7.8e-17 60.9 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KXT03017.1 - 4.1e-07 29.9 0.0 0.0016 18.4 0.0 3.2 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KXT03017.1 - 3e-05 23.8 0.0 0.059 13.2 0.0 2.7 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_3 PF08777.11 KXT03017.1 - 7.3e-05 22.7 0.0 0.0012 18.8 0.0 2.5 3 0 0 3 3 3 1 RNA binding motif RRM_7 PF16367.5 KXT03017.1 - 0.00036 20.6 0.1 0.052 13.7 0.0 3.1 3 1 0 3 3 3 1 RNA recognition motif RRM_5 PF13893.6 KXT03017.1 - 0.02 14.5 0.0 0.058 13.0 0.0 1.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KXT03017.1 - 0.025 14.8 0.1 1.9 8.7 0.0 3.3 3 1 1 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter OB_RNB PF08206.11 KXT03017.1 - 0.057 13.1 0.1 11 5.8 0.0 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain 14-3-3 PF00244.20 KXT03018.1 - 2e-106 354.5 6.5 2.3e-106 354.3 6.5 1.0 1 0 0 1 1 1 1 14-3-3 protein TerB PF05099.13 KXT03018.1 - 0.014 15.3 0.3 0.041 13.8 0.3 1.7 1 0 0 1 1 1 0 Tellurite resistance protein TerB TPR_19 PF14559.6 KXT03018.1 - 0.63 10.6 3.6 1.7 9.2 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_transf_28 PF03033.20 KXT03019.1 - 1.1e-15 57.9 0.1 2.2e-10 40.7 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain UIM PF02809.20 KXT03019.1 - 7.4e-06 25.5 23.9 6.3e-05 22.6 2.3 4.0 3 0 0 3 3 3 2 Ubiquitin interaction motif UDPGT PF00201.18 KXT03019.1 - 7.6e-06 25.0 0.0 1.3e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 KXT03019.1 - 1.8e-05 25.0 0.0 8e-05 22.9 0.0 2.1 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Glyco_tran_28_C PF04101.16 KXT03019.1 - 0.0018 18.3 0.4 0.011 15.8 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain RAP80_UIM PF18282.1 KXT03019.1 - 5.8 6.8 8.7 1.3 8.9 3.7 2.4 3 0 0 3 3 3 0 RAP80 N-terminal ubiquitin interaction motif RhoGEF PF00621.20 KXT03020.1 - 1.8e-19 70.7 0.1 3.7e-19 69.7 0.1 1.5 1 1 0 1 1 1 1 RhoGEF domain GRASP55_65 PF04495.14 KXT03021.1 - 8.7e-47 158.9 0.0 2e-43 148.0 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 KXT03021.1 - 0.00016 21.4 0.0 0.81 9.6 0.0 2.4 2 0 0 2 2 2 2 PDZ domain N_BRCA1_IG PF16158.5 KXT03022.1 - 3.5e-32 111.2 0.0 8.5e-32 109.9 0.0 1.7 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 KXT03022.1 - 2.8e-21 75.0 56.1 3.1e-06 26.9 10.3 4.4 4 0 0 4 4 4 4 Zinc finger, ZZ type C1_2 PF03107.16 KXT03022.1 - 0.00048 20.4 39.8 0.00074 19.8 1.6 4.6 4 0 0 4 4 4 3 C1 domain DUF1700 PF08006.11 KXT03022.1 - 1.4 8.4 3.6 2.5 7.6 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) BRD4_CDT PF17105.5 KXT03022.1 - 4 7.1 11.5 0.53 9.9 6.4 2.1 2 0 0 2 2 2 0 C-terminal domain of bromodomain protein 4 AMPK1_CBM PF16561.5 KXT03023.1 - 0.00032 20.8 0.1 0.00056 20.1 0.1 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase DUF951 PF06107.11 KXT03023.1 - 0.96 9.4 3.1 1.7 8.6 3.1 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF951) IFRD PF05004.13 KXT03024.1 - 3.8e-87 292.3 6.2 3.8e-87 292.3 6.2 1.6 2 0 0 2 2 2 1 Interferon-related developmental regulator (IFRD) ICL PF00463.21 KXT03025.1 - 5.7e-293 972.2 0.7 6.5e-293 972.0 0.7 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 KXT03025.1 - 4.4e-11 42.7 0.2 1.3e-10 41.2 0.0 1.8 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase FHA PF00498.26 KXT03026.1 - 4.6e-13 49.3 0.0 9.4e-13 48.3 0.0 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KXT03026.1 - 0.0079 16.5 0.0 0.021 15.1 0.0 1.7 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain His_Phos_1 PF00300.22 KXT03027.1 - 2.6e-11 43.6 0.1 1.4e-10 41.2 0.1 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_1 PF00300.22 KXT03028.1 - 2.6e-11 43.6 0.1 1.4e-10 41.2 0.1 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_1 PF00300.22 KXT03029.1 - 2.6e-11 43.6 0.1 1.4e-10 41.2 0.1 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) zf-MYND PF01753.18 KXT03031.1 - 5.5e-06 26.4 16.4 1.3e-05 25.1 16.4 1.7 1 1 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KXT03031.1 - 5.5 7.4 9.5 12 6.3 9.5 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding ADH_N_2 PF16884.5 KXT03032.1 - 1.8e-31 108.2 0.0 4e-31 107.1 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KXT03032.1 - 1.8e-17 63.5 0.1 2.9e-17 62.9 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXT03032.1 - 5.6e-11 43.6 0.3 1.3e-10 42.4 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase MBF1 PF08523.10 KXT03035.1 - 1.5e-22 79.9 1.4 1.5e-22 79.9 1.4 2.0 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 KXT03035.1 - 0.0025 17.9 0.0 0.0056 16.7 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix Scytalone_dh PF02982.14 KXT03036.1 - 4.3e-86 286.6 0.9 5.4e-86 286.3 0.9 1.1 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 KXT03036.1 - 2.4e-05 24.5 0.1 3.4e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain UDG PF03167.19 KXT03037.1 - 7.2e-19 68.3 0.0 1.1e-18 67.7 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily SnoaL_2 PF12680.7 KXT03039.1 - 1.9e-06 28.4 0.0 3.7e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like domain TFB6 PF17110.5 KXT03040.1 - 7.1e-57 191.9 0.0 9.1e-57 191.5 0.0 1.1 1 0 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH Mei5 PF10376.9 KXT03041.1 - 0.00041 20.3 14.1 0.00094 19.1 10.6 2.8 2 1 0 2 2 2 1 Double-strand recombination repair protein BBS1 PF14779.6 KXT03041.1 - 0.022 14.2 0.2 0.037 13.5 0.2 1.4 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 1 DUF3461 PF11944.8 KXT03041.1 - 0.045 13.9 0.1 0.083 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3461) DUF2262 PF10020.9 KXT03041.1 - 0.41 11.0 8.5 0.087 13.2 4.8 1.7 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2262) Lectin_N PF03954.14 KXT03041.1 - 0.5 10.1 2.7 0.37 10.6 0.2 1.9 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain DUF3848 PF12959.7 KXT03041.1 - 1.5 9.0 7.0 10 6.3 0.9 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3848) DUF4407 PF14362.6 KXT03041.1 - 4.9 6.4 8.8 8.2 5.7 8.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NAD_binding_2 PF03446.15 KXT03042.1 - 2e-28 99.6 0.2 3.4e-28 98.8 0.2 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KXT03042.1 - 1.1e-20 74.1 0.0 1.8e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Peptidase_S10 PF00450.22 KXT03043.1 - 9e-82 275.7 0.1 1.1e-81 275.4 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Aspzincin_M35 PF14521.6 KXT03044.1 - 1.8e-11 44.8 3.5 1.2e-05 25.9 0.4 3.0 2 1 0 2 2 2 2 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 KXT03044.1 - 0.0029 17.2 1.0 0.0073 15.9 0.2 1.9 2 0 0 2 2 2 1 Putative peptidase family DOPA_dioxygen PF08883.11 KXT03045.1 - 0.14 12.3 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Dopa 4,5-dioxygenase family Aspzincin_M35 PF14521.6 KXT03046.1 - 3.9e-07 30.7 7.1 7e-06 26.7 0.4 3.2 3 2 0 3 3 3 2 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 KXT03046.1 - 0.0021 17.7 0.2 0.0043 16.7 0.2 1.5 1 0 0 1 1 1 1 Putative peptidase family SBE2 PF17076.5 KXT03046.1 - 0.16 10.1 0.9 0.19 9.9 0.9 1.1 1 0 0 1 1 1 0 SBE2, cell-wall formation RNA_pol_Rpb1_5 PF04998.17 KXT03047.1 - 2.8e-79 266.3 0.2 1.8e-78 263.6 0.1 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KXT03047.1 - 5.8e-71 238.1 0.0 1.5e-70 236.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 KXT03047.1 - 1.6e-61 208.3 0.2 1.1e-59 202.4 0.2 2.3 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 KXT03047.1 - 1e-31 110.0 0.0 4.7e-31 107.9 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KXT03047.1 - 1.5e-27 95.6 1.2 8.1e-27 93.3 0.0 2.7 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 Antigen_Bd37 PF11641.8 KXT03047.1 - 0.036 13.6 0.3 0.097 12.2 0.3 1.7 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein ALIX_LYPXL_bnd PF13949.6 KXT03047.1 - 0.15 11.4 0.4 0.52 9.5 0.1 2.0 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV betaPIX_CC PF16523.5 KXT03047.1 - 0.15 11.9 1.0 6.1 6.7 0.2 2.8 2 0 0 2 2 2 0 betaPIX coiled coil Fungal_trans PF04082.18 KXT03048.1 - 2.6e-24 85.7 0.6 4.2e-24 85.0 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT03048.1 - 0.12 12.5 14.5 0.91 9.7 14.5 2.3 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain TolA_bind_tri PF16331.5 KXT03048.1 - 0.22 11.6 2.7 0.71 10.0 0.4 2.6 2 0 0 2 2 2 0 TolA binding protein trimerisation AHSA1 PF08327.11 KXT03050.1 - 0.069 13.4 0.0 0.14 12.4 0.0 1.5 1 1 0 1 1 1 0 Activator of Hsp90 ATPase homolog 1-like protein Helicase_C PF00271.31 KXT03050.1 - 0.16 12.4 0.0 0.29 11.5 0.0 1.4 1 0 0 1 1 1 0 Helicase conserved C-terminal domain ADIP PF11559.8 KXT03052.1 - 7.7e-37 126.7 15.0 7.7e-37 126.7 15.0 1.8 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding SpoU_methylase PF00588.19 KXT03052.1 - 0.33 11.1 1.2 4.7 7.4 1.0 2.2 2 0 0 2 2 2 0 SpoU rRNA Methylase family XhlA PF10779.9 KXT03052.1 - 2.1 8.6 4.4 1.8 8.9 2.0 2.2 2 0 0 2 2 2 0 Haemolysin XhlA bZIP_1 PF00170.21 KXT03052.1 - 4.8 7.4 12.9 8.1 6.6 0.2 3.7 2 1 1 3 3 3 0 bZIP transcription factor Btz PF09405.10 KXT03054.1 - 6.6e-20 71.7 4.3 6.6e-20 71.7 4.3 2.5 3 0 0 3 3 3 1 CASC3/Barentsz eIF4AIII binding Sec1 PF00995.23 KXT03055.1 - 8.5e-131 438.0 0.0 9.8e-131 437.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF2813 PF11398.8 KXT03055.1 - 0.022 14.0 0.0 0.059 12.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) HCV_core PF01542.18 KXT03055.1 - 0.1 13.0 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 Hepatitis C virus core protein p450 PF00067.22 KXT03056.1 - 6.8e-67 226.2 0.0 9e-67 225.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pox_A14 PF05767.12 KXT03057.1 - 0.066 13.4 0.6 0.066 13.4 0.6 2.0 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 RexB PF15968.5 KXT03057.1 - 0.1 13.0 2.0 0.21 12.1 2.0 1.4 1 0 0 1 1 1 0 Membrane-anchored ion channel, Abi component Acyl-CoA_dh_1 PF00441.24 KXT03058.1 - 4.2e-33 114.7 1.2 5.6e-33 114.3 1.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KXT03058.1 - 1.6e-23 82.7 0.5 2.6e-23 82.0 0.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KXT03058.1 - 7.4e-14 52.4 0.0 2.8e-13 50.5 0.0 2.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KXT03058.1 - 1.5e-06 28.5 0.1 2.2e-06 28.0 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain PsaL PF02605.15 KXT03058.1 - 0.039 13.6 0.1 0.089 12.4 0.1 1.5 1 1 0 1 1 1 0 Photosystem I reaction centre subunit XI HTH_ABP1_N PF18107.1 KXT03058.1 - 0.042 13.6 0.4 0.084 12.6 0.4 1.4 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain Acyl-CoA_dh_1 PF00441.24 KXT03059.1 - 4.2e-33 114.7 1.2 5.6e-33 114.3 1.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KXT03059.1 - 1.6e-23 82.7 0.5 2.6e-23 82.0 0.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KXT03059.1 - 7.4e-14 52.4 0.0 2.8e-13 50.5 0.0 2.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KXT03059.1 - 1.5e-06 28.5 0.1 2.2e-06 28.0 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain PsaL PF02605.15 KXT03059.1 - 0.039 13.6 0.1 0.089 12.4 0.1 1.5 1 1 0 1 1 1 0 Photosystem I reaction centre subunit XI HTH_ABP1_N PF18107.1 KXT03059.1 - 0.042 13.6 0.4 0.084 12.6 0.4 1.4 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain SBDS PF01172.18 KXT03062.1 - 7.2e-26 90.1 0.3 8.7e-26 89.8 0.3 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein FAD_binding_4 PF01565.23 KXT03063.1 - 1.5e-28 99.3 0.0 2.3e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 KXT03063.1 - 4.8e-07 29.7 0.2 7.4e-07 29.0 0.2 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain Complex1_LYR PF05347.15 KXT03075.1 - 1.9e-11 43.8 0.8 2.6e-11 43.4 0.8 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KXT03075.1 - 0.4 11.5 2.6 0.92 10.3 2.6 1.5 1 1 0 1 1 1 0 Complex1_LYR-like Forkhead PF00250.18 KXT03076.1 - 0.00077 19.7 0.1 0.0036 17.5 0.1 2.2 2 0 0 2 2 2 1 Forkhead domain NOA36 PF06524.12 KXT03078.1 - 6.4 6.0 6.5 8.3 5.6 6.5 1.1 1 0 0 1 1 1 0 NOA36 protein PKD_channel PF08016.12 KXT03079.1 - 0.037 12.7 11.6 0.52 8.9 4.2 2.3 2 0 0 2 2 2 0 Polycystin cation channel Abhydrolase_3 PF07859.13 KXT03080.1 - 2.5e-13 50.4 0.0 3.2e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold 4HBT_2 PF13279.6 KXT03084.1 - 7.6e-25 87.8 0.1 1.1e-24 87.2 0.1 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 KXT03084.1 - 0.0029 17.9 0.0 0.0057 17.0 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily TctC PF03401.14 KXT03084.1 - 0.16 11.0 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter family receptor Serglycin PF04360.12 KXT03085.1 - 0.23 11.4 2.3 0.55 10.2 2.3 1.5 1 0 0 1 1 1 0 Serglycin Aminotran_1_2 PF00155.21 KXT03086.1 - 4.4e-41 141.3 0.0 5.6e-41 140.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KXT03086.1 - 0.0034 16.0 0.0 0.0047 15.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_3 PF00202.21 KXT03086.1 - 0.01 14.5 0.0 0.016 13.9 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-III Glyco_hydro_18 PF00704.28 KXT03087.1 - 6.8e-76 256.0 2.2 8e-76 255.7 2.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 WLM PF08325.10 KXT03088.1 - 7.9e-28 97.8 2.5 3.3e-27 95.8 2.4 2.1 1 1 0 1 1 1 1 WLM domain DUF45 PF01863.17 KXT03088.1 - 2.3e-06 27.8 1.5 2.3e-06 27.8 1.5 2.2 3 0 0 3 3 3 1 Protein of unknown function DUF45 zf-RanBP PF00641.18 KXT03088.1 - 0.0023 17.2 3.8 0.0023 17.2 3.8 2.6 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others zf-RING_10 PF16685.5 KXT03088.1 - 0.45 10.7 2.5 1.3 9.2 2.5 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 DZR PF12773.7 KXT03088.1 - 0.74 9.9 7.9 1.7 8.7 7.9 1.6 1 0 0 1 1 1 0 Double zinc ribbon Ras PF00071.22 KXT03089.1 - 1.1e-40 138.9 0.0 1.3e-40 138.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXT03089.1 - 7.2e-13 48.8 0.0 1.1e-12 48.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXT03089.1 - 1.5e-05 24.5 0.0 1.9e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KXT03089.1 - 0.00053 20.1 0.0 0.00079 19.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KXT03089.1 - 0.0045 16.5 0.0 0.055 13.0 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain NB-ARC PF00931.22 KXT03089.1 - 0.017 14.3 0.0 0.032 13.4 0.0 1.4 2 0 0 2 2 2 0 NB-ARC domain PRK PF00485.18 KXT03089.1 - 0.071 12.8 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family RsgA_GTPase PF03193.16 KXT03089.1 - 0.091 12.7 0.0 1.7 8.6 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Hpr_kinase_C PF07475.12 KXT03089.1 - 0.21 11.1 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain Ras PF00071.22 KXT03090.1 - 1.1e-40 138.9 0.0 1.3e-40 138.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXT03090.1 - 7.2e-13 48.8 0.0 1.1e-12 48.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXT03090.1 - 1.5e-05 24.5 0.0 1.9e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KXT03090.1 - 0.00053 20.1 0.0 0.00079 19.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KXT03090.1 - 0.0045 16.5 0.0 0.055 13.0 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain NB-ARC PF00931.22 KXT03090.1 - 0.017 14.3 0.0 0.032 13.4 0.0 1.4 2 0 0 2 2 2 0 NB-ARC domain PRK PF00485.18 KXT03090.1 - 0.071 12.8 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family RsgA_GTPase PF03193.16 KXT03090.1 - 0.091 12.7 0.0 1.7 8.6 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Hpr_kinase_C PF07475.12 KXT03090.1 - 0.21 11.1 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain PACT_coil_coil PF10495.9 KXT03091.1 - 5.5e-23 81.3 0.1 5.5e-23 81.3 0.1 6.1 6 3 1 7 7 5 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Cnn_1N PF07989.11 KXT03091.1 - 3.5e-20 71.9 11.2 3.5e-20 71.9 11.2 18.4 5 3 12 18 18 14 3 Centrosomin N-terminal motif 1 Spc7 PF08317.11 KXT03091.1 - 4e-08 32.5 227.6 0.0012 17.8 24.4 10.5 1 1 9 11 11 11 9 Spc7 kinetochore protein bZIP_1 PF00170.21 KXT03091.1 - 0.0023 18.0 1.6 0.0023 18.0 1.6 16.5 14 5 4 19 19 17 2 bZIP transcription factor Lebercilin PF15619.6 KXT03091.1 - 0.0025 17.5 22.0 0.0025 17.5 22.0 11.0 2 2 8 10 10 8 2 Ciliary protein causing Leber congenital amaurosis disease GAS PF13851.6 KXT03091.1 - 0.0025 17.2 17.4 0.0025 17.2 17.4 12.2 1 1 10 12 12 11 4 Growth-arrest specific micro-tubule binding Spc110_C PF18520.1 KXT03091.1 - 0.0026 17.3 5.7 0.0075 15.8 0.2 4.6 4 0 0 4 4 4 1 Spindle pole body component 110 C-terminal domain DUF745 PF05335.13 KXT03091.1 - 0.0043 16.8 12.7 0.0043 16.8 12.7 10.8 1 1 8 10 10 8 2 Protein of unknown function (DUF745) Tropomyosin_1 PF12718.7 KXT03091.1 - 0.0043 17.2 17.4 0.0043 17.2 17.4 12.5 1 1 11 12 12 10 1 Tropomyosin like SOGA PF11365.8 KXT03091.1 - 0.005 17.9 9.8 0.005 17.9 9.8 14.3 2 2 9 14 14 9 1 Protein SOGA DUF4407 PF14362.6 KXT03091.1 - 0.62 9.4 195.6 0.052 12.9 22.3 9.1 1 1 9 10 10 9 0 Domain of unknown function (DUF4407) HMMR_N PF15905.5 KXT03091.1 - 1.1 8.7 211.4 0.041 13.4 23.1 9.9 1 1 7 9 9 8 0 Hyaluronan mediated motility receptor N-terminal GhoS PF11080.8 KXT03091.1 - 2.5 8.1 8.3 2.8 8.0 0.1 4.4 4 1 0 4 4 4 0 Endoribonuclease GhoS RrnaAD PF00398.20 KXT03093.1 - 0.00032 19.9 0.0 0.027 13.5 0.0 2.4 2 1 0 2 2 2 2 Ribosomal RNA adenine dimethylase ZnuA PF01297.17 KXT03093.1 - 0.054 12.9 0.0 0.17 11.2 0.0 1.6 1 1 1 2 2 2 0 Zinc-uptake complex component A periplasmic Peptidase_C54 PF03416.19 KXT03094.1 - 1.7e-99 332.7 0.0 2.2e-99 332.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 PAS_9 PF13426.7 KXT03095.1 - 3.7e-28 97.8 0.0 2.2e-16 60.0 0.0 3.4 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.12 KXT03095.1 - 4.1e-17 62.3 0.0 2e-10 40.8 0.0 3.6 3 0 0 3 3 3 3 PAS fold GATA PF00320.27 KXT03095.1 - 1.1e-14 53.7 4.8 2.5e-14 52.6 4.8 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.25 KXT03095.1 - 2.8e-13 49.9 0.0 1.5e-05 25.0 0.0 3.7 3 1 0 3 3 3 3 PAS fold PAS_11 PF14598.6 KXT03095.1 - 1.8e-09 37.7 0.0 0.0005 20.2 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 KXT03095.1 - 1e-05 25.8 0.0 0.98 9.7 0.0 3.6 3 0 0 3 3 3 2 PAS fold PAS_2 PF08446.11 KXT03095.1 - 0.001 19.7 0.0 0.66 10.7 0.0 3.5 3 0 0 3 3 3 1 PAS fold Trimer_CC PF08954.11 KXT03096.1 - 0.014 14.9 0.3 0.037 13.6 0.0 1.8 2 0 0 2 2 2 0 Trimerisation motif BLOC1_2 PF10046.9 KXT03096.1 - 0.11 12.8 0.2 0.15 12.4 0.2 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sugar_tr PF00083.24 KXT03097.1 - 1.4e-43 149.5 22.9 1.8e-43 149.1 22.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXT03097.1 - 1.1e-14 54.2 29.4 2e-14 53.3 29.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Gpi1 PF05024.15 KXT03098.1 - 3.7e-77 258.7 8.3 5.8e-77 258.0 8.3 1.3 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) Gpi1 PF05024.15 KXT03099.1 - 3.7e-77 258.7 8.3 5.8e-77 258.0 8.3 1.3 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) Gpi1 PF05024.15 KXT03100.1 - 4.3e-77 258.4 8.3 6.7e-77 257.8 8.3 1.3 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) Histone PF00125.24 KXT03102.1 - 4.8e-23 82.0 1.3 5.9e-23 81.7 1.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXT03102.1 - 6.5e-05 23.1 1.0 0.00011 22.5 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KXT03102.1 - 0.00027 21.4 0.0 0.00045 20.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF1018 PF06252.12 KXT03102.1 - 0.031 15.3 0.7 0.042 14.8 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) RP-C PF03428.13 KXT03102.1 - 0.058 13.0 0.1 0.14 11.8 0.1 1.6 1 1 0 1 1 1 0 Replication protein C N-terminal domain Lgl_C PF08596.10 KXT03104.1 - 8.1e-117 390.2 0.0 1.3e-116 389.6 0.0 1.3 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.32 KXT03104.1 - 1.6e-05 25.6 0.3 0.03 15.2 0.1 4.2 3 0 0 3 3 3 1 WD domain, G-beta repeat RDD PF06271.12 KXT03105.1 - 0.14 12.4 5.0 3.5 7.8 2.9 2.5 2 0 0 2 2 2 0 RDD family DUF1656 PF07869.12 KXT03105.1 - 0.46 10.5 4.7 1.7 8.7 1.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) PID_2 PF14719.6 KXT03106.1 - 0.13 12.2 1.3 0.94 9.3 1.0 2.1 2 0 0 2 2 2 0 Phosphotyrosine interaction domain (PTB/PID) RDD PF06271.12 KXT03106.1 - 0.16 12.2 5.0 3.7 7.8 2.9 2.5 2 0 0 2 2 2 0 RDD family DUF1656 PF07869.12 KXT03106.1 - 0.5 10.4 4.7 1.8 8.7 1.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) Fungal_trans PF04082.18 KXT03107.1 - 7.6e-13 48.1 0.4 3.6e-12 45.9 0.0 2.0 1 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT03107.1 - 1.4e-07 31.5 9.8 2.8e-07 30.5 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GLE1 PF07817.13 KXT03107.1 - 0.076 12.2 0.2 2.9 7.0 0.1 2.5 2 0 0 2 2 2 0 GLE1-like protein 2-oxoacid_dh PF00198.23 KXT03108.1 - 9.2e-80 267.4 0.2 1.3e-79 266.9 0.2 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KXT03108.1 - 6.4e-17 61.1 2.8 1.4e-16 60.1 2.8 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KXT03108.1 - 0.00037 20.3 0.4 0.015 15.2 0.1 2.4 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 KXT03108.1 - 0.011 16.4 0.2 1.5 9.5 0.0 2.5 1 1 1 2 2 2 0 HlyD family secretion protein GCV_H PF01597.19 KXT03108.1 - 0.015 15.2 0.4 0.04 13.8 0.4 1.7 1 0 0 1 1 1 0 Glycine cleavage H-protein RnfC_N PF13375.6 KXT03108.1 - 0.017 15.1 0.9 0.066 13.2 0.1 2.4 2 1 0 2 2 2 0 RnfC Barrel sandwich hybrid domain Raftlin PF15250.6 KXT03108.1 - 0.059 12.1 13.1 0.083 11.6 13.1 1.1 1 0 0 1 1 1 0 Raftlin Velvet PF11754.8 KXT03108.1 - 0.076 12.9 7.3 0.11 12.4 7.3 1.2 1 0 0 1 1 1 0 Velvet factor Presenilin PF01080.17 KXT03108.1 - 0.15 10.8 12.7 0.22 10.3 12.7 1.1 1 0 0 1 1 1 0 Presenilin Spore_coat_CotO PF14153.6 KXT03108.1 - 0.27 11.2 20.9 0.45 10.4 20.9 1.4 1 0 0 1 1 1 0 Spore coat protein CotO CDC45 PF02724.14 KXT03108.1 - 0.68 8.1 13.5 0.9 7.8 13.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4551 PF15087.6 KXT03108.1 - 0.92 8.3 11.1 1.3 7.8 11.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Mitofilin PF09731.9 KXT03108.1 - 1.1 8.0 22.5 1.6 7.5 22.5 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein FAM76 PF16046.5 KXT03108.1 - 1.5 8.1 14.8 7.1 5.9 13.9 2.0 2 0 0 2 2 2 0 FAM76 protein GAGA_bind PF06217.12 KXT03108.1 - 1.9 8.7 11.6 3 8.0 11.6 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.12 KXT03108.1 - 2.6 7.8 19.6 3.9 7.2 19.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 LAP1C PF05609.12 KXT03108.1 - 2.7 7.0 14.0 3.9 6.5 14.0 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Apt1 PF10351.9 KXT03108.1 - 3.2 6.5 13.3 4.4 6.1 13.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Trypan_PARP PF05887.11 KXT03108.1 - 5.3 7.0 22.2 11 6.1 22.2 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Neur_chan_memb PF02932.16 KXT03108.1 - 8.7 6.3 7.5 12 5.9 7.5 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Histone_H2A_C PF16211.5 KXT03109.1 - 6.6e-21 73.8 2.3 1.2e-20 73.0 2.3 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KXT03109.1 - 5.6e-17 62.3 0.0 7.6e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXT03109.1 - 1.1e-05 25.6 0.0 1.4e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF4597 PF15366.6 KXT03110.1 - 0.037 13.8 1.7 0.037 13.8 1.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4597) Nop PF01798.18 KXT03111.1 - 4.6e-84 281.5 0.0 4.6e-84 281.5 0.0 1.9 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KXT03111.1 - 8.6e-20 70.9 0.4 8.6e-20 70.9 0.4 2.8 3 1 0 3 3 3 1 NOP5NT (NUC127) domain Dicty_REP PF05086.12 KXT03112.1 - 5.9 4.7 6.5 8.3 4.2 6.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein COesterase PF00135.28 KXT03113.1 - 6.1e-73 246.4 0.1 8.8e-73 245.9 0.1 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXT03113.1 - 2.9e-06 27.3 0.2 9.4e-06 25.6 0.2 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXT03113.1 - 0.019 14.5 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Peptidase_C14 PF00656.22 KXT03114.1 - 5.7e-62 209.9 0.0 7e-62 209.6 0.0 1.1 1 0 0 1 1 1 1 Caspase domain SnoaL PF07366.12 KXT03115.1 - 2.6e-05 24.0 0.0 7e-05 22.6 0.0 1.8 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KXT03115.1 - 0.039 14.6 0.0 0.1 13.3 0.0 1.6 1 1 0 1 1 1 0 SnoaL-like domain COG5 PF10392.9 KXT03117.1 - 2.6e-39 134.4 2.2 7.1e-39 133.0 0.3 2.6 2 0 0 2 2 2 1 Golgi transport complex subunit 5 DUF5344 PF17279.2 KXT03117.1 - 0.021 15.4 1.1 0.66 10.6 0.4 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5344) Rpp20 PF12328.8 KXT03117.1 - 0.03 14.3 0.8 0.067 13.1 0.8 1.5 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P NPV_P10 PF05531.12 KXT03117.1 - 0.64 10.5 3.6 1.4 9.4 0.5 2.7 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Aldolase_II PF00596.21 KXT03118.1 - 1.5e-28 100.0 0.3 2.1e-28 99.5 0.3 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain EthD PF07110.11 KXT03119.1 - 1.1e-08 36.1 0.1 1.3e-08 35.9 0.1 1.1 1 0 0 1 1 1 1 EthD domain DUF1330 PF07045.11 KXT03119.1 - 0.025 14.9 0.0 0.043 14.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1330) MmlI PF09448.10 KXT03119.1 - 0.18 12.3 0.2 0.44 11.0 0.2 1.7 1 1 0 1 1 1 0 Methylmuconolactone methyl-isomerase JAB PF01398.21 KXT03120.1 - 2.4e-10 40.4 0.0 4.9e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 KXT03120.1 - 1.5e-05 25.1 1.0 3e-05 24.2 1.0 1.5 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.6 KXT03120.1 - 6.7e-05 22.6 0.0 0.00023 20.9 0.0 1.9 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain SSXT PF05030.12 KXT03120.1 - 0.087 12.5 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 SSXT protein (N-terminal region) TBCC PF07986.12 KXT03121.1 - 3.6e-29 100.9 0.8 8.3e-29 99.8 0.2 2.0 2 0 0 2 2 2 1 Tubulin binding cofactor C TBCC_N PF16752.5 KXT03121.1 - 5.1e-09 36.6 0.2 6.3e-08 33.1 0.0 2.2 2 0 0 2 2 2 1 Tubulin-specific chaperone C N-terminal domain TBCC PF07986.12 KXT03122.1 - 3.6e-29 100.9 0.8 8.3e-29 99.8 0.2 2.0 2 0 0 2 2 2 1 Tubulin binding cofactor C TBCC_N PF16752.5 KXT03122.1 - 5.1e-09 36.6 0.2 6.3e-08 33.1 0.0 2.2 2 0 0 2 2 2 1 Tubulin-specific chaperone C N-terminal domain TBCC PF07986.12 KXT03123.1 - 3.6e-29 100.9 0.8 8.3e-29 99.8 0.2 2.0 2 0 0 2 2 2 1 Tubulin binding cofactor C TBCC_N PF16752.5 KXT03123.1 - 5.1e-09 36.6 0.2 6.3e-08 33.1 0.0 2.2 2 0 0 2 2 2 1 Tubulin-specific chaperone C N-terminal domain TBCC PF07986.12 KXT03125.1 - 3.6e-29 100.9 0.8 8.3e-29 99.8 0.2 2.0 2 0 0 2 2 2 1 Tubulin binding cofactor C TBCC_N PF16752.5 KXT03125.1 - 5.1e-09 36.6 0.2 6.3e-08 33.1 0.0 2.2 2 0 0 2 2 2 1 Tubulin-specific chaperone C N-terminal domain ASF1_hist_chap PF04729.13 KXT03127.1 - 3.1e-74 248.0 0.0 4.3e-74 247.6 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone DUF1139 PF06599.11 KXT03127.1 - 0.26 10.6 0.8 0.39 10.1 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1139) zf-CCCH_4 PF18044.1 KXT03128.1 - 2.8e-05 23.8 2.9 5.3e-05 22.9 2.9 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KXT03128.1 - 8.5e-05 22.5 4.9 0.00016 21.6 4.9 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KXT03128.1 - 0.0075 16.2 1.9 0.013 15.4 1.9 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 KXT03128.1 - 0.69 10.5 4.2 1.4 9.5 4.2 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Nucleoporin_FG PF13634.6 KXT03128.1 - 7.4 7.5 125.5 0.74 10.7 28.1 5.5 2 1 3 5 5 5 0 Nucleoporin FG repeat region Phage_GP20 PF06810.11 KXT03130.1 - 0.36 10.6 8.5 0.76 9.6 1.8 3.7 2 1 2 4 4 4 0 Phage minor structural protein GP20 Fib_alpha PF08702.10 KXT03130.1 - 9 6.5 11.5 0.4 10.9 1.1 3.2 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family Glyco_hydro_16 PF00722.21 KXT03131.1 - 1.3e-06 28.0 0.1 3.3e-06 26.7 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Pro-kuma_activ PF09286.11 KXT03132.1 - 2.1e-34 118.8 0.4 3.5e-33 114.9 0.1 2.2 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KXT03132.1 - 0.02 14.2 0.2 0.037 13.3 0.2 1.5 2 0 0 2 2 2 0 Subtilase family DUF4283 PF14111.6 KXT03132.1 - 0.15 11.5 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4283) SAM_2 PF07647.17 KXT03134.1 - 2.3e-05 24.4 0.0 4.7e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KXT03134.1 - 0.0068 16.8 0.1 0.014 15.9 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) MerR-DNA-bind PF09278.11 KXT03134.1 - 4.3 8.0 6.3 0.62 10.6 0.1 2.7 3 0 0 3 3 3 0 MerR, DNA binding DUF2370 PF10176.9 KXT03135.1 - 1e-83 280.5 0.1 1.8e-83 279.7 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2370) PBP1_TM PF14812.6 KXT03135.1 - 0.76 10.2 5.8 1.8 9.0 5.8 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2370 PF10176.9 KXT03136.1 - 1e-83 280.5 0.1 1.8e-83 279.7 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2370) PBP1_TM PF14812.6 KXT03136.1 - 0.76 10.2 5.8 1.8 9.0 5.8 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Exo_endo_phos PF03372.23 KXT03138.1 - 4.6e-20 72.1 0.1 3.7e-19 69.2 0.1 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 KXT03138.1 - 2e-09 37.1 0.1 7.8e-05 22.4 1.8 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KXT03138.1 - 2.7e-07 30.8 0.2 0.0027 18.1 0.1 2.4 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) CCDC14 PF15254.6 KXT03138.1 - 3.4 6.2 7.7 4.8 5.7 7.7 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 Aminotran_3 PF00202.21 KXT03141.1 - 3.4e-40 138.0 0.0 1.2e-19 70.3 0.0 3.6 3 1 0 3 3 3 2 Aminotransferase class-III AAA_26 PF13500.6 KXT03141.1 - 3.6e-20 72.6 0.0 9.5e-20 71.3 0.0 1.6 1 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KXT03141.1 - 0.12 12.7 0.0 0.31 11.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Complex1_LYR_2 PF13233.6 KXT03142.1 - 5.4e-05 23.9 1.5 7.3e-05 23.4 1.5 1.3 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KXT03142.1 - 0.00021 21.3 0.1 0.00033 20.6 0.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) R3H PF01424.22 KXT03143.1 - 2.3e-11 43.5 0.0 5.6e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 R3H domain G-patch PF01585.23 KXT03143.1 - 5.9e-09 35.7 8.2 1.2e-08 34.7 8.2 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KXT03143.1 - 8.1e-05 22.6 5.2 8.1e-05 22.6 5.2 2.4 2 0 0 2 2 2 1 G-patch domain Abhydrolase_1 PF00561.20 KXT03144.1 - 1.8e-10 40.9 0.0 3.5e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXT03144.1 - 5e-09 35.8 0.0 1e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 KXT03144.1 - 0.04 13.6 0.0 0.077 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.21 KXT03144.1 - 0.16 11.4 0.0 0.61 9.5 0.0 1.9 1 1 0 1 1 1 0 Prolyl oligopeptidase family Mito_carr PF00153.27 KXT03145.1 - 2e-56 187.9 0.4 1.1e-21 76.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HA2 PF04408.23 KXT03146.1 - 5.2e-17 62.1 0.1 5.2e-17 62.1 0.1 1.8 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KXT03146.1 - 2.1e-12 47.2 0.0 4.8e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KXT03146.1 - 3.3e-12 46.7 0.0 1e-11 45.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXT03146.1 - 1.6e-07 31.3 0.0 4.1e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KXT03146.1 - 3.5e-06 27.3 0.0 8e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXT03146.1 - 6.3e-05 23.3 0.0 0.00012 22.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KXT03146.1 - 0.0035 16.4 0.0 0.0064 15.6 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 KXT03146.1 - 0.0059 17.1 0.0 0.019 15.5 0.0 1.9 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 KXT03146.1 - 0.015 15.0 0.0 0.034 13.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF815 PF05673.13 KXT03146.1 - 0.066 12.4 0.0 0.16 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 KXT03146.1 - 0.081 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_30 PF13604.6 KXT03146.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KXT03146.1 - 0.17 11.9 0.0 12 5.9 0.0 3.2 2 1 0 2 2 2 0 AAA domain Sec34 PF04136.15 KXT03147.1 - 1.8e-51 174.0 0.5 3.3e-51 173.1 0.5 1.5 1 0 0 1 1 1 1 Sec34-like family Phasin_2 PF09361.10 KXT03147.1 - 0.059 13.6 3.4 0.31 11.3 0.6 2.8 2 0 0 2 2 2 0 Phasin protein DUF2857 PF11198.8 KXT03147.1 - 0.12 12.2 1.2 0.25 11.1 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2857) FHA PF00498.26 KXT03150.1 - 6.1e-17 61.7 0.0 1e-16 61.0 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KXT03150.1 - 1.6e-06 28.4 0.0 6.7e-05 23.1 0.0 2.3 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kelch_4 PF13418.6 KXT03151.1 - 2e-33 114.2 11.1 1.1e-10 41.4 0.0 6.7 6 1 1 7 7 7 4 Galactose oxidase, central domain Kelch_3 PF13415.6 KXT03151.1 - 3.1e-30 103.8 12.3 6.3e-09 35.9 0.0 7.7 8 0 0 8 8 8 4 Galactose oxidase, central domain DUF4110 PF13422.6 KXT03151.1 - 5.7e-29 100.0 4.4 5.7e-29 100.0 4.4 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4110) Kelch_6 PF13964.6 KXT03151.1 - 1.8e-22 78.8 2.1 7.7e-06 26.0 0.1 5.5 5 0 0 5 5 5 4 Kelch motif Kelch_5 PF13854.6 KXT03151.1 - 3.2e-21 74.9 4.2 3e-05 23.9 0.0 6.1 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 KXT03151.1 - 4.7e-16 58.0 3.1 0.0047 16.9 0.0 6.1 5 1 0 5 5 5 4 Kelch motif Kelch_1 PF01344.25 KXT03151.1 - 8.5e-14 50.9 3.1 3.2e-06 26.6 0.0 5.8 5 1 0 5 5 5 2 Kelch motif MCPVI PF02993.14 KXT03151.1 - 0.046 13.5 1.9 0.097 12.5 1.9 1.5 1 0 0 1 1 1 0 Minor capsid protein VI PBP1_TM PF14812.6 KXT03152.1 - 0.028 14.8 6.0 0.092 13.1 6.0 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 KXT03152.1 - 0.095 12.0 2.9 0.13 11.6 2.9 1.2 1 0 0 1 1 1 0 NOA36 protein GRIM-19 PF06212.12 KXT03153.1 - 4.5e-23 81.7 0.1 5.8e-23 81.3 0.1 1.2 1 0 0 1 1 1 1 GRIM-19 protein DUF1686 PF07937.11 KXT03153.1 - 0.2 11.5 0.0 0.24 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1686) Lactamase_B_3 PF13483.6 KXT03154.1 - 2.9e-06 27.3 0.0 5.5e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 KXT03154.1 - 0.00018 21.1 0.0 0.00027 20.5 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain N6-adenineMlase PF10237.9 KXT03155.1 - 1.7e-52 177.4 0.0 2.2e-52 177.1 0.0 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase MTS PF05175.14 KXT03155.1 - 0.18 11.3 0.0 0.99 8.9 0.0 2.0 1 1 1 2 2 2 0 Methyltransferase small domain Sec7 PF01369.20 KXT03156.1 - 1.4e-26 93.3 0.0 2.9e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 KXT03156.1 - 6.8e-18 65.2 0.0 1.5e-17 64.0 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Tektin PF03148.14 KXT03156.1 - 0.0014 17.4 0.2 0.0024 16.7 0.2 1.2 1 0 0 1 1 1 1 Tektin family LETM1 PF07766.13 KXT03157.1 - 1.5e-19 70.4 0.2 2.5e-14 53.3 0.2 2.1 2 0 0 2 2 2 2 LETM1-like protein DUF3176 PF11374.8 KXT03158.1 - 1.5e-11 44.4 1.8 8.4e-11 42.0 1.8 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3176) WSC PF01822.19 KXT03158.1 - 6e-10 39.2 15.8 1.5e-09 37.9 15.8 1.7 1 0 0 1 1 1 1 WSC domain SKG6 PF08693.10 KXT03158.1 - 3.4e-08 32.8 5.8 3.4e-08 32.8 5.8 2.4 3 0 0 3 3 3 1 Transmembrane alpha-helix domain Phage_holin_2_4 PF16082.5 KXT03158.1 - 0.011 15.4 0.3 0.038 13.7 0.3 1.9 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like DUF4448 PF14610.6 KXT03158.1 - 0.011 15.5 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Mid2 PF04478.12 KXT03158.1 - 0.14 12.0 0.7 0.32 10.8 0.7 1.6 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor EphA2_TM PF14575.6 KXT03158.1 - 0.16 12.9 0.0 0.44 11.5 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain BAT2_N PF07001.11 KXT03158.1 - 0.17 12.3 5.0 0.36 11.3 5.0 1.5 1 0 0 1 1 1 0 BAT2 N-terminus PTP_tm PF18861.1 KXT03158.1 - 1.1 9.3 5.3 0.82 9.6 2.9 2.0 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J HNH PF01844.23 KXT03159.1 - 0.014 15.6 1.4 0.04 14.1 1.4 1.8 1 1 0 1 1 1 0 HNH endonuclease FSH1 PF03959.13 KXT03160.1 - 1.9e-30 106.1 0.0 2.6e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 KXT03160.1 - 0.018 14.7 0.0 0.025 14.2 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KXT03160.1 - 0.087 12.6 0.5 0.97 9.2 0.2 2.6 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Caps_synth PF05704.12 KXT03182.1 - 0.069 12.5 0.0 0.093 12.1 0.0 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein F-box-like PF12937.7 KXT03184.1 - 0.011 15.6 1.0 0.011 15.6 1.0 2.0 2 0 0 2 2 2 0 F-box-like F-box PF00646.33 KXT03184.1 - 0.1 12.5 0.2 0.1 12.5 0.2 2.3 2 0 0 2 2 2 0 F-box domain Asparaginase_2 PF01112.18 KXT03185.1 - 9.5e-49 166.1 0.1 2.4e-32 112.2 0.0 2.4 2 0 0 2 2 2 2 Asparaginase FTHFS PF01268.19 KXT03185.1 - 0.15 10.2 0.1 0.24 9.6 0.1 1.2 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase UDPG_MGDP_dh_N PF03721.14 KXT03186.1 - 2.9e-57 193.3 0.0 5.3e-57 192.4 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 KXT03186.1 - 3.9e-31 107.6 1.0 3.1e-26 91.8 0.2 3.2 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 KXT03186.1 - 2.5e-29 101.3 0.0 7.1e-29 99.9 0.0 1.8 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_binding_2 PF03446.15 KXT03186.1 - 0.012 15.8 0.0 0.2 11.8 0.0 2.7 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Ldh_1_N PF00056.23 KXT03186.1 - 0.019 15.1 0.4 10 6.2 0.0 3.1 2 1 1 3 3 3 0 lactate/malate dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KXT03186.1 - 0.026 14.8 0.7 0.15 12.3 0.0 2.5 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 KXT03186.1 - 0.032 14.1 0.1 0.24 11.3 0.0 2.4 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 KXT03186.1 - 0.036 14.0 0.1 0.61 10.0 0.0 2.5 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus MTS PF05175.14 KXT03186.1 - 0.11 12.0 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Nuf2 PF03800.14 KXT03187.1 - 3.3e-42 143.9 3.0 3.9e-42 143.7 0.1 2.4 2 0 0 2 2 2 1 Nuf2 family DHR10 PF18595.1 KXT03187.1 - 6.4e-31 106.8 23.4 6.4e-31 106.8 23.4 3.6 3 0 0 3 3 3 2 Designed helical repeat protein 10 domain GAS PF13851.6 KXT03187.1 - 0.14 11.5 62.9 0.91 8.8 23.4 3.3 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Tropomyosin_1 PF12718.7 KXT03187.1 - 0.65 10.2 64.2 0.045 13.9 20.7 3.3 1 1 2 3 3 3 0 Tropomyosin like Spc7 PF08317.11 KXT03187.1 - 2.8 6.8 62.3 0.4 9.5 22.6 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein FUSC PF04632.12 KXT03187.1 - 5.8 5.3 28.7 8.1 4.8 21.2 2.3 1 1 1 2 2 2 0 Fusaric acid resistance protein family FRG2 PF15315.6 KXT03188.1 - 0.36 11.0 9.6 1 9.5 9.6 1.7 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 Corazonin PF17308.2 KXT03189.1 - 0.083 13.3 0.1 0.1 13.0 0.1 1.1 1 0 0 1 1 1 0 Pro-corazonin PET117 PF15786.5 KXT03189.1 - 0.72 10.2 5.1 4.9 7.5 5.1 2.0 1 1 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial Pmp3 PF01679.17 KXT03191.1 - 1.6e-19 69.8 8.6 2.1e-19 69.4 8.6 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator FAD_binding_3 PF01494.19 KXT03193.1 - 3e-73 247.1 0.0 3.8e-73 246.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KXT03193.1 - 1.9e-38 132.1 0.1 3.6e-38 131.2 0.1 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 KXT03193.1 - 0.0011 18.2 0.0 0.025 13.8 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXT03193.1 - 0.0069 16.6 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXT03193.1 - 0.01 15.5 0.2 0.58 9.7 0.0 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXT03193.1 - 0.015 15.8 0.0 0.043 14.4 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 KXT03193.1 - 0.036 13.6 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Lycopene_cycl PF05834.12 KXT03193.1 - 0.094 11.8 0.0 0.2 10.7 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein Adaptin_N PF01602.20 KXT03194.1 - 4.1e-94 316.0 0.1 6.5e-94 315.4 0.1 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KXT03194.1 - 3e-13 50.2 1.4 1.8e-11 44.3 0.1 3.9 2 2 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KXT03194.1 - 3.3e-10 40.2 7.3 6.9e-05 23.2 0.1 5.3 3 2 2 5 5 5 3 HEAT repeats HEAT PF02985.22 KXT03194.1 - 5.3e-08 32.5 6.0 0.0068 16.6 0.0 5.9 7 0 0 7 7 7 2 HEAT repeat Cohesin_HEAT PF12765.7 KXT03194.1 - 6e-06 26.5 0.3 0.11 12.8 0.1 2.9 2 0 0 2 2 2 2 HEAT repeat associated with sister chromatid cohesion RTP1_C1 PF10363.9 KXT03194.1 - 0.056 13.6 0.1 7.3 6.8 0.0 3.3 2 1 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Telomere_reg-2 PF10193.9 KXT03194.1 - 0.1 13.1 0.6 2 8.9 0.1 3.3 4 1 0 4 4 4 0 Telomere length regulation protein GATase PF00117.28 KXT03197.1 - 3.8e-37 127.9 0.0 6e-37 127.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.22 KXT03197.1 - 7e-30 102.9 0.1 1.7e-29 101.7 0.1 1.7 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.17 KXT03197.1 - 2.4e-10 40.0 0.1 1.4e-05 24.4 0.1 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 KXT03197.1 - 2.7e-05 24.0 0.0 7.3e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 KXT03197.1 - 0.00054 18.9 0.2 0.0016 17.3 0.1 1.8 2 0 0 2 2 2 1 tRNA methyl transferase QueC PF06508.13 KXT03197.1 - 0.0011 18.5 0.1 0.0095 15.5 0.0 2.3 2 1 0 2 2 2 1 Queuosine biosynthesis protein QueC ThiI PF02568.14 KXT03197.1 - 0.0072 15.9 0.1 0.025 14.2 0.0 1.9 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) Arginosuc_synth PF00764.19 KXT03197.1 - 0.021 14.1 0.1 0.045 13.0 0.1 1.5 1 0 0 1 1 1 0 Arginosuccinate synthase Lon_C PF05362.13 KXT03198.1 - 1.8e-68 230.1 0.3 3.5e-68 229.2 0.3 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KXT03198.1 - 4.6e-30 105.1 0.1 1.1e-29 103.9 0.1 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KXT03198.1 - 1.5e-23 83.6 0.0 6.3e-23 81.6 0.0 2.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXT03198.1 - 5.2e-09 36.2 0.0 2.1e-08 34.2 0.0 2.2 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 KXT03198.1 - 2.9e-07 30.3 0.0 8e-07 28.9 0.0 1.8 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 KXT03198.1 - 7.1e-06 26.5 1.0 3.3e-05 24.3 0.0 2.8 3 1 0 3 3 2 1 AAA ATPase domain AAA_2 PF07724.14 KXT03198.1 - 1e-05 25.7 0.0 3.7e-05 23.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 KXT03198.1 - 4.9e-05 23.1 0.0 0.00012 21.9 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 KXT03198.1 - 8.7e-05 22.4 0.0 0.00026 20.9 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KXT03198.1 - 8.8e-05 22.3 0.1 0.00099 18.9 0.0 2.6 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KXT03198.1 - 0.00013 21.3 0.0 0.00024 20.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 KXT03198.1 - 0.00052 20.3 0.0 0.011 16.0 0.0 3.2 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KXT03198.1 - 0.0028 17.8 0.6 0.0094 16.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KXT03198.1 - 0.013 15.5 0.0 0.034 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KXT03198.1 - 0.016 15.8 9.1 0.019 15.4 0.0 3.1 1 1 1 2 2 1 0 AAA domain NTPase_1 PF03266.15 KXT03198.1 - 0.02 14.8 0.0 0.19 11.7 0.0 2.5 2 0 0 2 2 2 0 NTPase RNA_helicase PF00910.22 KXT03198.1 - 0.028 14.8 0.0 0.061 13.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 KXT03198.1 - 0.033 14.7 0.0 0.1 13.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KXT03198.1 - 0.037 13.9 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 KXT03198.1 - 0.052 12.7 0.0 0.12 11.5 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain Mg_chelatase PF01078.21 KXT03198.1 - 0.052 12.9 0.1 0.14 11.5 0.1 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 KXT03198.1 - 0.053 13.4 0.0 0.21 11.5 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase Rad17 PF03215.15 KXT03198.1 - 0.06 13.3 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_7 PF12775.7 KXT03198.1 - 0.076 12.5 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 KXT03198.1 - 0.079 12.9 0.2 0.46 10.4 0.0 2.4 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 KXT03198.1 - 0.083 12.5 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KXT03198.1 - 0.086 12.8 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 KXT03198.1 - 0.14 11.9 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_PrkA PF08298.11 KXT03198.1 - 0.16 10.8 1.2 1.9 7.3 0.1 2.5 2 1 1 3 3 3 0 PrkA AAA domain SOAR PF16533.5 KXT03198.1 - 0.42 10.6 2.6 1.9 8.5 1.2 2.5 2 0 0 2 2 2 0 STIM1 Orai1-activating region NMD3 PF04981.13 KXT03199.1 - 1.9e-78 263.3 1.5 3.2e-78 262.6 1.5 1.4 1 0 0 1 1 1 1 NMD3 family Nif11 PF07862.11 KXT03199.1 - 0.016 15.5 1.1 0.034 14.5 0.2 2.0 2 0 0 2 2 2 0 Nif11 domain HypA PF01155.19 KXT03199.1 - 0.024 14.7 2.5 1.2 9.1 0.1 2.6 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA HscB_4_cys PF18256.1 KXT03199.1 - 0.034 14.0 0.6 0.086 12.7 0.6 1.7 1 0 0 1 1 1 0 Co-chaperone HscB tetracysteine metal binding motif DUF3797 PF12677.7 KXT03199.1 - 0.069 13.0 0.1 0.84 9.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) DZR PF12773.7 KXT03199.1 - 0.17 11.9 4.6 1.5 8.9 2.0 2.6 2 1 0 2 2 2 0 Double zinc ribbon TackOD1 PF18551.1 KXT03199.1 - 0.87 9.2 4.3 12 5.5 0.6 2.5 1 1 0 2 2 2 0 Thaumarchaeal output domain 1 zinc-ribbons_6 PF07191.12 KXT03199.1 - 6.6 6.8 6.2 7.1 6.7 0.8 2.8 2 1 0 2 2 2 0 zinc-ribbons Aldedh PF00171.22 KXT03200.1 - 5.6e-184 612.0 1.4 6.3e-184 611.8 1.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KXT03200.1 - 0.027 13.9 0.2 1.1 8.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Eno-Rase_NADH_b PF12242.8 KXT03200.1 - 0.078 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Skp1_POZ PF03931.15 KXT03201.1 - 5.4e-05 23.3 0.0 0.00022 21.3 0.0 1.9 1 1 0 1 1 1 1 Skp1 family, tetramerisation domain SGL PF08450.12 KXT03201.1 - 0.0099 15.5 0.0 0.011 15.3 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region IBR PF01485.21 KXT03202.1 - 0.0065 16.7 8.7 0.0065 16.7 8.7 3.4 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain CENP-B_dimeris PF09026.10 KXT03202.1 - 0.034 14.5 6.5 1.7 9.0 2.1 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DXP_reductoisom PF02670.16 KXT03202.1 - 0.13 13.0 1.1 0.26 12.0 0.3 1.9 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Glyco_transf_17 PF04724.13 KXT03203.1 - 7.6e-54 183.1 0.0 9.6e-40 136.7 0.0 2.6 2 1 0 2 2 2 2 Glycosyltransferase family 17 DUF3446 PF11928.8 KXT03205.1 - 0.59 10.5 3.7 1.3 9.3 1.0 2.1 2 0 0 2 2 2 0 Early growth response N-terminal domain PNTB PF02233.16 KXT03206.1 - 1.2e-170 568.4 24.1 1.2e-170 568.4 24.1 2.2 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 KXT03206.1 - 5.4e-75 251.4 0.6 5.4e-75 251.4 0.6 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 KXT03206.1 - 2e-37 128.5 0.4 8.6e-37 126.5 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 KXT03206.1 - 1.5e-30 105.5 3.9 1.5e-30 105.5 3.9 5.3 4 1 1 5 5 4 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 KXT03206.1 - 1.4e-06 27.8 0.5 0.6 9.4 0.0 3.6 2 1 1 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 KXT03206.1 - 0.01 15.1 0.4 0.04 13.2 0.4 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TPP_enzyme_M PF00205.22 KXT03206.1 - 0.02 14.6 0.3 0.085 12.6 0.1 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain ADH_zinc_N PF00107.26 KXT03206.1 - 0.021 14.8 0.6 0.1 12.6 0.3 2.5 2 0 0 2 2 2 0 Zinc-binding dehydrogenase CP_ATPgrasp_1 PF04174.13 KXT03206.1 - 0.084 11.9 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 A circularly permuted ATPgrasp GIDA PF01134.22 KXT03206.1 - 0.1 11.6 1.3 0.19 10.8 1.3 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A FliM PF02154.15 KXT03206.1 - 0.12 12.2 0.1 0.34 10.8 0.1 1.7 2 0 0 2 2 2 0 Flagellar motor switch protein FliM FAD_binding_2 PF00890.24 KXT03206.1 - 0.22 10.6 3.2 1.2 8.2 2.6 2.2 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.6 KXT03206.1 - 0.9 9.8 4.8 0.33 11.2 0.7 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain TPT PF03151.16 KXT03212.1 - 5.4e-37 127.7 18.1 6.4e-37 127.5 18.1 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KXT03212.1 - 1.4e-15 57.3 22.5 2e-15 56.8 22.5 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KXT03212.1 - 0.0002 21.6 33.2 0.048 13.8 11.3 2.2 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 KXT03214.1 - 5.4e-37 127.7 18.1 6.4e-37 127.5 18.1 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KXT03214.1 - 1.4e-15 57.3 22.5 2e-15 56.8 22.5 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KXT03214.1 - 0.0002 21.6 33.2 0.048 13.8 11.3 2.2 2 0 0 2 2 2 2 EamA-like transporter family Sugar_tr PF00083.24 KXT03217.1 - 5.7e-05 22.2 0.0 6.2e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXT03217.1 - 0.034 13.1 0.1 0.039 12.9 0.1 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF3100 PF11299.8 KXT03217.1 - 0.16 11.4 0.8 0.21 10.9 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3100) Ribosomal_L34 PF00468.17 KXT03218.1 - 0.092 12.7 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L34 GDPD PF03009.17 KXT03222.1 - 1.2e-09 38.3 0.0 2.1e-09 37.5 0.0 1.5 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Fungal_trans PF04082.18 KXT03223.1 - 7.6e-20 71.0 0.0 4.8e-19 68.4 0.0 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT03223.1 - 0.00032 20.8 7.6 0.00032 20.8 7.6 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BTB PF00651.31 KXT03224.1 - 2.7e-11 43.7 0.0 4.6e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Rota_NSP3 PF01665.16 KXT03224.1 - 0.048 12.8 0.1 0.075 12.1 0.1 1.2 1 0 0 1 1 1 0 Rotavirus non-structural protein NSP3 Fungal_trans PF04082.18 KXT03225.1 - 7.6e-20 71.0 0.0 4.8e-19 68.4 0.0 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT03225.1 - 0.00032 20.8 7.6 0.00032 20.8 7.6 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_4 PF01565.23 KXT03226.1 - 3.4e-17 62.5 0.0 5.5e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DUF4428 PF14471.6 KXT03226.1 - 0.0086 16.0 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4428) Actin PF00022.19 KXT03227.1 - 4e-88 295.8 0.0 1.1e-52 179.0 0.0 2.0 1 1 1 2 2 2 2 Actin MreB_Mbl PF06723.13 KXT03227.1 - 0.0098 14.7 0.0 0.39 9.5 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein zf-CCHC_4 PF14392.6 KXT03227.1 - 0.16 11.7 1.3 0.72 9.6 0.0 2.3 2 0 0 2 2 2 0 Zinc knuckle LtrA PF06772.11 KXT03228.1 - 3.2e-23 82.5 30.1 9.9e-23 80.9 23.5 2.3 2 0 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) SPC12 PF06645.13 KXT03228.1 - 5.6 7.1 11.5 0.16 12.0 0.6 3.7 3 2 1 4 4 4 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Sugar_tr PF00083.24 KXT03229.1 - 1.8e-93 313.9 22.9 2.2e-93 313.6 22.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXT03229.1 - 6.3e-13 48.4 51.4 1.2e-08 34.3 16.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Tti2 PF10521.9 KXT03230.1 - 3.9e-72 243.1 2.5 6.6e-72 242.4 2.5 1.3 1 0 0 1 1 1 1 Tti2 family PolyA_pol PF01743.20 KXT03230.1 - 2.5e-24 86.1 1.1 1.4e-23 83.7 1.1 2.1 1 1 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 KXT03230.1 - 2.7e-08 33.4 0.0 6.8e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.6 KXT03230.1 - 0.0054 16.7 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative Glyco_hydro_127 PF07944.12 KXT03233.1 - 1.5e-92 310.8 0.0 1.9e-92 310.5 0.0 1.0 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_127 PF07944.12 KXT03234.1 - 7.5e-93 311.8 0.0 9.4e-93 311.5 0.0 1.0 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 Redoxin PF08534.10 KXT03235.1 - 8.3e-27 93.7 0.0 9.9e-27 93.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KXT03235.1 - 1.9e-06 27.8 0.0 2.7e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family DUF3299 PF11736.8 KXT03235.1 - 0.019 15.0 1.7 0.13 12.3 0.2 2.4 2 1 0 3 3 3 0 Protein of unknown function (DUF3299) Lipase_2 PF01674.18 KXT03236.1 - 3.3e-08 33.3 0.0 5.7e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 2) Abhydrolase_6 PF12697.7 KXT03236.1 - 4.1e-05 24.3 1.6 5.5e-05 23.9 1.7 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXT03236.1 - 0.00099 18.8 0.1 0.0035 17.0 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXT03236.1 - 0.011 15.0 0.1 0.019 14.2 0.1 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 BAAT_C PF08840.11 KXT03236.1 - 0.22 11.4 0.0 0.33 10.8 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal BTB PF00651.31 KXT03237.1 - 8.9e-17 61.3 0.0 5.8e-16 58.7 0.0 2.1 1 1 1 2 2 2 1 BTB/POZ domain CLP_protease PF00574.23 KXT03238.1 - 0.14 12.0 0.0 0.43 10.4 0.0 1.7 2 0 0 2 2 2 0 Clp protease OTU PF02338.19 KXT03239.1 - 7.7e-10 39.4 0.0 2e-09 38.0 0.0 1.7 1 1 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KXT03239.1 - 0.011 15.2 0.5 14 5.1 0.0 3.1 2 1 1 3 3 3 0 Peptidase C65 Otubain UBA PF00627.31 KXT03239.1 - 0.086 12.8 0.1 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 UBA/TS-N domain CUE PF02845.16 KXT03239.1 - 0.11 12.3 0.1 0.22 11.3 0.1 1.5 1 0 0 1 1 1 0 CUE domain Rib_5-P_isom_A PF06026.14 KXT03240.1 - 1.8e-40 138.3 0.0 3.3e-40 137.5 0.0 1.4 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) ThiF PF00899.21 KXT03240.1 - 1.9e-16 60.2 0.0 3.1e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 ThiF family TFIIS_C PF01096.18 KXT03241.1 - 1.6e-17 63.1 3.2 1.6e-17 63.1 3.2 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) DZR PF12773.7 KXT03241.1 - 2.1e-05 24.5 6.4 0.0055 16.7 0.2 2.5 2 1 0 2 2 2 2 Double zinc ribbon RNA_POL_M_15KD PF02150.16 KXT03241.1 - 0.0027 17.6 0.6 0.0027 17.6 0.6 3.2 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit zf-ribbon_3 PF13248.6 KXT03241.1 - 0.0027 17.0 10.1 2.7 7.5 0.1 4.2 4 0 0 4 4 4 1 zinc-ribbon domain zf-RRN7 PF11781.8 KXT03241.1 - 0.0068 16.1 8.8 1.8 8.3 0.1 4.2 5 0 0 5 5 4 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 IBR PF01485.21 KXT03241.1 - 0.0077 16.4 7.3 0.14 12.4 0.1 2.8 2 1 0 2 2 2 1 IBR domain, a half RING-finger domain zinc_ribbon_2 PF13240.6 KXT03241.1 - 0.0081 15.9 13.3 0.77 9.6 0.1 4.1 4 0 0 4 4 4 1 zinc-ribbon domain zinc_ribbon_4 PF13717.6 KXT03241.1 - 0.013 15.4 6.0 1 9.3 0.3 4.0 4 0 0 4 4 4 0 zinc-ribbon domain zf-CSL PF05207.13 KXT03241.1 - 0.064 13.0 1.0 0.064 13.0 1.0 2.1 2 1 0 2 2 1 0 CSL zinc finger Zn-ribbon_8 PF09723.10 KXT03241.1 - 0.099 12.8 12.2 1 9.5 0.7 3.2 2 1 1 3 3 3 0 Zinc ribbon domain zf_UBZ PF18439.1 KXT03241.1 - 0.11 12.1 12.7 0.88 9.2 0.2 4.0 3 1 1 4 4 4 0 Ubiquitin-Binding Zinc Finger HypA PF01155.19 KXT03241.1 - 0.13 12.3 8.4 1.2 9.1 0.6 2.6 1 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TF_Zn_Ribbon PF08271.12 KXT03241.1 - 0.18 11.4 14.6 0.89 9.1 0.2 4.0 2 2 1 4 4 4 0 TFIIB zinc-binding Lar_restr_allev PF14354.6 KXT03241.1 - 0.21 12.0 12.6 2.9 8.3 1.1 3.0 2 2 0 2 2 2 0 Restriction alleviation protein Lar Baculo_LEF5_C PF11792.8 KXT03241.1 - 0.47 10.2 5.4 0.59 9.8 1.5 2.7 2 1 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain zf-3CxxC PF13695.6 KXT03241.1 - 0.98 9.9 8.4 4.5 7.8 0.2 2.8 2 1 1 3 3 3 0 Zinc-binding domain eIF-5_eIF-2B PF01873.17 KXT03241.1 - 1.4 8.8 6.0 6.1 6.8 0.7 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 zf-FPG_IleRS PF06827.14 KXT03241.1 - 1.4 8.8 10.4 14 5.7 0.4 4.0 4 0 0 4 4 4 0 Zinc finger found in FPG and IleRS DUF3268 PF11672.8 KXT03241.1 - 1.5 9.2 5.8 0.45 10.9 0.7 2.3 2 1 1 3 3 3 0 zinc-finger-containing domain Nudix_N_2 PF14803.6 KXT03241.1 - 1.7 8.7 11.6 13 5.9 3.0 3.5 2 2 0 2 2 2 0 Nudix N-terminal Mu-like_Com PF10122.9 KXT03241.1 - 1.8 8.1 10.1 0.35 10.3 2.2 2.9 3 1 0 3 3 3 0 Mu-like prophage protein Com Rubredoxin_2 PF18073.1 KXT03241.1 - 2.1 8.2 11.2 11 5.8 0.5 3.9 4 0 0 4 4 4 0 Rubredoxin metal binding domain zf-IS66 PF13005.7 KXT03241.1 - 2.1 8.8 10.4 31 5.1 0.1 4.1 3 1 1 4 4 4 0 zinc-finger binding domain of transposase IS66 zf-3CxxC_2 PF17180.4 KXT03241.1 - 2.6 8.9 9.5 12 6.8 1.2 3.1 2 1 1 3 3 3 0 Zinc-binding domain OrfB_Zn_ribbon PF07282.11 KXT03241.1 - 3.3 7.7 11.2 17 5.4 2.9 3.2 2 2 0 3 3 3 0 Putative transposase DNA-binding domain Prim_Zn_Ribbon PF08273.12 KXT03241.1 - 3.5 8.0 0.0 3.5 8.0 0.0 3.4 3 1 0 3 3 3 0 Zinc-binding domain of primase-helicase zf-RING_7 PF02591.15 KXT03241.1 - 3.6 7.9 8.7 12 6.1 0.0 3.7 4 1 0 4 4 4 0 C4-type zinc ribbon domain RecR PF02132.15 KXT03241.1 - 5.4 6.7 13.7 9.1 5.9 2.1 3.9 3 1 0 3 3 3 0 RecR protein C1_2 PF03107.16 KXT03241.1 - 5.6 7.4 11.9 18 5.8 3.1 3.3 2 2 0 2 2 2 0 C1 domain Zn_Tnp_IS1595 PF12760.7 KXT03241.1 - 6.9 6.7 10.6 2.8 8.0 4.1 2.8 2 2 1 3 3 3 0 Transposase zinc-ribbon domain DNA_RNApol_7kD PF03604.13 KXT03241.1 - 6.9 6.4 10.7 39 4.0 3.4 3.7 3 1 1 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit Ribosomal_S27e PF01667.17 KXT03241.1 - 7.6 6.3 9.4 22 4.8 1.3 3.6 3 1 0 3 3 3 0 Ribosomal protein S27 Imm53 PF15580.6 KXT03242.1 - 0.13 12.0 0.5 1.6 8.5 0.0 2.2 2 0 0 2 2 2 0 Immunity protein 53 Ribosomal_S5_C PF03719.15 KXT03244.1 - 3.9e-22 77.5 0.0 2.8e-21 74.7 0.1 2.2 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 KXT03244.1 - 1.1e-16 60.5 0.1 2.4e-16 59.5 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Med27 PF11571.8 KXT03246.1 - 0.056 13.8 0.1 0.078 13.3 0.1 1.3 1 0 0 1 1 1 0 Mediator complex subunit 27 HEAT_2 PF13646.6 KXT03247.1 - 7.2e-29 100.0 3.1 6.9e-14 52.0 0.7 3.0 2 2 1 3 3 3 2 HEAT repeats HEAT_PBS PF03130.16 KXT03247.1 - 1e-21 75.3 1.5 0.0097 16.5 0.1 6.4 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT PF02985.22 KXT03247.1 - 5.8e-07 29.2 6.1 0.036 14.3 0.0 6.3 8 0 0 8 8 8 2 HEAT repeat HEAT_EZ PF13513.6 KXT03247.1 - 1.9e-05 25.0 3.5 1.4 9.5 0.1 5.2 3 2 3 6 6 6 2 HEAT-like repeat CNTF PF01110.17 KXT03247.1 - 0.079 12.3 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 Ciliary neurotrophic factor RsfS PF02410.15 KXT03248.1 - 1.1e-14 54.6 0.0 3.2e-14 53.2 0.0 1.8 1 1 0 1 1 1 1 Ribosomal silencing factor during starvation NPM1-C PF16276.5 KXT03248.1 - 0.012 15.6 1.0 1.3 9.0 0.3 2.6 2 0 0 2 2 2 0 Nucleophosmin C-terminal domain NAD_binding_2 PF03446.15 KXT03250.1 - 1.1e-36 126.4 0.0 1.7e-36 125.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KXT03250.1 - 1.4e-23 83.4 0.0 2.6e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KXT03250.1 - 0.0051 17.4 0.0 0.011 16.3 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.22 KXT03250.1 - 0.061 14.1 0.0 0.13 13.0 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold adh_short PF00106.25 KXT03251.1 - 3.3e-13 49.5 2.0 2.9e-10 39.9 0.0 2.7 3 0 0 3 3 3 2 short chain dehydrogenase KR PF08659.10 KXT03251.1 - 8.5e-05 22.5 0.9 0.00012 22.0 0.0 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KXT03251.1 - 0.00052 19.6 0.2 0.0019 17.7 0.1 2.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.6 KXT03251.1 - 0.00052 19.6 0.8 0.0016 18.0 0.0 2.1 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase RDD PF06271.12 KXT03251.1 - 0.12 12.5 1.6 0.15 12.2 0.3 1.8 2 0 0 2 2 2 0 RDD family adh_short PF00106.25 KXT03252.1 - 3.3e-13 49.5 2.0 2.9e-10 39.9 0.0 2.7 3 0 0 3 3 3 2 short chain dehydrogenase KR PF08659.10 KXT03252.1 - 8.5e-05 22.5 0.9 0.00012 22.0 0.0 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KXT03252.1 - 0.00052 19.6 0.2 0.0019 17.7 0.1 2.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.6 KXT03252.1 - 0.00052 19.6 0.8 0.0016 18.0 0.0 2.1 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase RDD PF06271.12 KXT03252.1 - 0.12 12.5 1.6 0.15 12.2 0.3 1.8 2 0 0 2 2 2 0 RDD family Peptidase_C12 PF01088.21 KXT03253.1 - 5.4e-56 189.7 0.0 6.1e-56 189.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DUF2114 PF09887.9 KXT03253.1 - 0.21 10.0 0.0 0.28 9.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2114) DUF4185 PF13810.6 KXT03254.1 - 2.2e-05 23.9 1.6 3.2e-05 23.3 1.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4185) PhnG PF06754.12 KXT03254.1 - 0.014 15.3 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnG ABC_tran PF00005.27 KXT03255.1 - 1.7e-20 73.9 0.0 6.5e-09 36.4 0.0 3.4 2 1 0 2 2 2 2 ABC transporter SbcCD_C PF13558.6 KXT03255.1 - 2.7e-05 24.3 0.0 0.087 13.1 0.1 2.7 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 KXT03255.1 - 0.026 14.3 7.4 1.3 8.7 0.3 3.2 2 1 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KXT03255.1 - 0.082 13.4 0.4 0.082 13.4 0.4 2.5 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 KXT03255.1 - 0.083 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KXT03255.1 - 0.096 13.0 1.4 1.1 9.5 0.5 3.1 2 1 0 2 2 2 0 AAA domain BCIP PF13862.6 KXT03256.1 - 1.4e-72 243.8 0.6 1.9e-72 243.4 0.6 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein V-ATPase_H_N PF03224.14 KXT03256.1 - 0.055 12.8 1.1 0.11 11.8 1.1 1.4 1 1 0 1 1 1 0 V-ATPase subunit H VID27_N PF17748.1 KXT03256.1 - 0.15 11.9 0.1 0.15 11.9 0.1 1.8 2 0 0 2 2 2 0 VID27 N-terminal region OPT PF03169.15 KXT03257.1 - 1.7e-136 456.4 48.6 2e-136 456.2 48.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein zf-C3HC4_2 PF13923.6 KXT03258.1 - 1.8e-11 43.7 11.0 3.4e-11 42.8 11.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXT03258.1 - 2.9e-09 36.6 10.8 6.2e-09 35.6 10.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXT03258.1 - 6.3e-09 35.7 8.2 1.3e-08 34.7 8.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KXT03258.1 - 3e-08 33.5 10.9 7e-08 32.3 10.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KXT03258.1 - 5e-07 29.5 7.7 9.9e-07 28.5 7.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXT03258.1 - 1.2e-06 28.7 10.9 2.4e-06 27.8 10.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 KXT03258.1 - 9.8e-06 25.6 9.6 2.1e-05 24.5 9.6 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 KXT03258.1 - 4.6e-05 23.2 2.5 8.5e-05 22.4 2.5 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 KXT03258.1 - 0.00012 21.9 9.1 0.00036 20.3 7.6 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KXT03258.1 - 0.00016 21.9 6.0 0.00047 20.4 6.0 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain Mob_synth_C PF06463.13 KXT03258.1 - 0.00043 20.2 1.7 0.0011 18.9 1.7 1.7 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C SAP PF02037.27 KXT03258.1 - 0.00089 18.9 0.0 0.002 17.8 0.0 1.6 1 0 0 1 1 1 1 SAP domain zf-RING_10 PF16685.5 KXT03258.1 - 0.0032 17.6 4.0 0.0063 16.6 4.0 1.4 1 0 0 1 1 1 1 zinc RING finger of MSL2 U-box PF04564.15 KXT03258.1 - 0.03 14.5 0.0 0.1 12.8 0.0 1.9 1 0 0 1 1 1 0 U-box domain zf-RING_4 PF14570.6 KXT03258.1 - 0.043 13.6 7.8 0.22 11.4 8.0 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 KXT03258.1 - 0.043 13.9 1.5 0.096 12.7 1.5 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-P11 PF03854.14 KXT03258.1 - 0.047 13.4 5.0 0.1 12.3 5.0 1.5 1 0 0 1 1 1 0 P-11 zinc finger Rubredoxin_2 PF18073.1 KXT03258.1 - 0.049 13.4 1.1 0.12 12.2 1.1 1.7 1 0 0 1 1 1 0 Rubredoxin metal binding domain DUF1272 PF06906.11 KXT03258.1 - 0.5 10.5 7.1 1.1 9.4 7.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) ADH_N PF08240.12 KXT03260.1 - 7.7e-29 99.8 0.5 1.4e-28 99.0 0.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXT03260.1 - 5.7e-22 78.1 0.1 9.6e-22 77.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXT03260.1 - 0.00042 21.4 0.0 0.00069 20.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KXT03260.1 - 0.0022 17.4 0.1 0.0039 16.6 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.25 KXT03260.1 - 0.003 17.0 0.4 0.0055 16.2 0.4 1.5 1 0 0 1 1 1 1 short chain dehydrogenase AlaDh_PNT_C PF01262.21 KXT03260.1 - 0.0061 15.9 1.3 0.0096 15.2 1.3 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UMP1 PF05348.11 KXT03262.1 - 9.6e-39 132.3 0.0 1.4e-38 131.8 0.0 1.2 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Pkinase PF00069.25 KXT03263.1 - 4.1e-22 78.8 0.0 6e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 KXT03263.1 - 1.5e-11 44.7 6.7 6.1e-06 26.9 0.1 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat HEAT PF02985.22 KXT03263.1 - 3.7e-11 42.3 6.4 0.003 17.7 0.0 6.4 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 KXT03263.1 - 8.9e-06 26.0 1.4 1.1 9.8 0.0 3.8 2 1 2 4 4 4 3 HEAT repeats Pkinase_Tyr PF07714.17 KXT03263.1 - 2.4e-05 23.7 0.0 4.1e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_EZ PF13513.6 KXT03263.1 - 0.00021 21.7 0.9 0.017 15.6 0.2 3.1 2 0 0 2 2 2 1 HEAT-like repeat Ge1_WD40 PF16529.5 KXT03263.1 - 0.0021 17.1 0.0 0.15 10.9 0.0 2.5 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Kinase-like PF14531.6 KXT03263.1 - 0.026 13.9 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Cnd1 PF12717.7 KXT03263.1 - 0.029 14.4 0.5 3.2 7.8 0.0 3.6 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 ANAPC4_WD40 PF12894.7 KXT03263.1 - 0.034 14.5 0.0 6.8 7.1 0.0 3.5 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain zf-RING_5 PF14634.6 KXT03264.1 - 1.3e-07 31.5 7.1 2.1e-07 30.8 7.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KXT03264.1 - 0.00073 19.4 6.6 0.0013 18.6 6.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXT03264.1 - 0.00074 19.3 5.6 0.0014 18.5 5.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXT03264.1 - 0.0036 17.1 5.6 0.0068 16.2 5.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KXT03264.1 - 0.0037 17.6 6.4 0.0067 16.7 6.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 KXT03264.1 - 0.011 15.8 1.9 0.024 14.8 1.9 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KXT03264.1 - 0.014 15.4 4.6 0.016 15.2 3.1 1.9 1 1 1 2 2 2 0 RING-type zinc-finger DUF4868 PF16162.5 KXT03264.1 - 0.014 15.3 0.3 0.02 14.8 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4868) zf-C3HC4_2 PF13923.6 KXT03264.1 - 0.068 13.0 6.9 0.15 11.9 6.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KXT03264.1 - 0.078 12.8 3.0 0.14 11.9 3.0 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain MAD PF05557.13 KXT03264.1 - 0.15 10.4 9.6 0.19 10.0 9.6 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Fmp27_WPPW PF10359.9 KXT03264.1 - 1.9 7.3 8.9 2.5 6.9 8.9 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Mod_r PF07200.13 KXT03264.1 - 3.3 7.8 11.8 5.8 7.0 11.8 1.4 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein V_ATPase_I PF01496.19 KXT03264.1 - 3.4 5.5 5.9 4.1 5.2 5.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ZapB PF06005.12 KXT03264.1 - 4.9 7.7 9.5 12 6.4 9.4 1.8 1 1 0 1 1 1 0 Cell division protein ZapB bZIP_1 PF00170.21 KXT03264.1 - 8.2 6.6 10.4 0.69 10.0 1.9 2.8 2 1 1 3 3 3 0 bZIP transcription factor DENN PF02141.21 KXT03265.1 - 3.6e-40 137.9 0.1 6.3e-40 137.1 0.1 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KXT03265.1 - 4.2e-05 24.2 0.0 0.00012 22.7 0.0 1.9 1 0 0 1 1 1 1 uDENN domain Elongin_A PF06881.11 KXT03265.1 - 0.013 16.1 5.6 0.045 14.3 5.6 2.0 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A MCC-bdg_PDZ PF10506.9 KXT03265.1 - 0.41 10.7 5.0 0.13 12.3 1.6 2.0 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome CENP-F_leu_zip PF10473.9 KXT03265.1 - 2.6 8.1 18.6 0.046 13.7 6.5 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cnn_1N PF07989.11 KXT03265.1 - 4.8 7.4 13.0 0.34 11.1 2.7 2.6 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 APG6_N PF17675.1 KXT03265.1 - 5.6 7.5 23.3 5.3 7.6 20.0 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF724 PF05266.14 KXT03265.1 - 6.9 6.4 11.9 13 5.6 11.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF724) adh_short PF00106.25 KXT03266.1 - 4.3e-15 55.7 0.0 5.3e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT03266.1 - 2.4e-10 40.4 0.0 3e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT03266.1 - 5.2e-08 33.0 0.0 9.6e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 KR domain Asp PF00026.23 KXT03267.1 - 5.6e-69 233.0 1.0 6.9e-69 232.7 1.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXT03267.1 - 1.1e-06 29.1 0.4 0.0045 17.2 0.0 3.0 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KXT03267.1 - 0.029 15.0 1.3 1.2 9.8 0.2 3.4 3 1 0 3 3 3 0 Aspartyl protease bZIP_1 PF00170.21 KXT03268.1 - 0.00014 21.8 7.3 0.00014 21.8 7.3 1.9 2 0 0 2 2 2 1 bZIP transcription factor RR_TM4-6 PF06459.12 KXT03268.1 - 0.94 9.3 5.8 1.8 8.3 5.8 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 bZIP_Maf PF03131.17 KXT03268.1 - 2.4 8.7 10.8 1.5 9.4 8.6 1.7 1 1 0 1 1 1 0 bZIP Maf transcription factor SOBP PF15279.6 KXT03268.1 - 3.7 8.1 7.1 5.6 7.5 7.1 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Clr5 PF14420.6 KXT03269.1 - 1.8e-09 37.7 1.1 1.8e-09 37.7 1.1 2.3 3 0 0 3 3 3 1 Clr5 domain TPR_12 PF13424.6 KXT03269.1 - 0.042 14.1 3.2 1.7 9.0 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KXT03269.1 - 0.1 12.8 0.3 1 9.6 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Baseplate_J PF04865.14 KXT03269.1 - 0.21 10.7 0.0 0.33 10.1 0.0 1.2 1 0 0 1 1 1 0 Baseplate J-like protein STOP PF05217.12 KXT03269.1 - 6.5 7.1 7.7 0.26 11.6 1.2 2.0 2 0 0 2 2 2 0 STOP protein Amidohydro_1 PF01979.20 KXT03270.1 - 8.6e-28 97.6 0.0 1.5e-27 96.9 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXT03270.1 - 2.6e-14 53.5 0.0 1.3e-06 28.2 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family Urease_alpha PF00449.20 KXT03270.1 - 0.00047 20.5 0.2 0.0013 19.0 0.2 1.7 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Amidohydro_1 PF01979.20 KXT03271.1 - 8.6e-28 97.6 0.0 1.5e-27 96.9 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXT03271.1 - 2.6e-14 53.5 0.0 1.3e-06 28.2 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family Urease_alpha PF00449.20 KXT03271.1 - 0.00047 20.5 0.2 0.0013 19.0 0.2 1.7 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain She9_MDM33 PF05546.11 KXT03272.1 - 1.2e-52 178.6 7.7 2.1e-52 177.9 7.7 1.4 1 0 0 1 1 1 1 She9 / Mdm33 family HTH_32 PF13565.6 KXT03272.1 - 1.6 9.4 4.8 2 9.1 0.4 3.0 3 0 0 3 3 3 0 Homeodomain-like domain Ribosom_S12_S23 PF00164.25 KXT03273.1 - 1.7e-29 101.7 1.2 2.3e-29 101.3 1.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S12 PF17487.2 KXT03273.1 - 0.12 13.2 0.0 0.35 11.6 0.0 1.8 1 1 0 1 1 1 0 Ribosomal protein S12 TRAPPC-Trs85 PF12739.7 KXT03275.1 - 2.7e-109 365.8 0.0 8.7e-109 364.2 0.0 1.7 2 0 0 2 2 2 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Nipped-B_C PF12830.7 KXT03276.1 - 3.2e-35 121.8 1.9 1.7e-32 112.9 0.0 4.0 2 1 0 2 2 2 1 Sister chromatid cohesion C-terminus Cnd1 PF12717.7 KXT03276.1 - 1.5e-08 34.8 4.6 0.0018 18.3 0.1 3.7 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.7 KXT03276.1 - 3.7e-08 33.5 1.9 3.7e-08 33.5 1.9 3.9 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 KXT03276.1 - 1.2e-06 28.2 0.4 0.25 11.7 0.2 5.3 5 0 0 5 5 5 1 HEAT repeat Adaptin_N PF01602.20 KXT03276.1 - 9.9e-06 24.4 5.8 2.3e-05 23.2 0.3 3.3 2 1 1 3 3 3 1 Adaptin N terminal region RTP1_C1 PF10363.9 KXT03276.1 - 0.005 17.0 0.3 0.037 14.2 0.3 2.7 1 1 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 1 DUF507 PF04368.13 KXT03276.1 - 0.21 11.5 1.4 0.59 10.1 1.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF507) HEAT_EZ PF13513.6 KXT03276.1 - 3.2 8.4 5.4 21 5.7 0.1 4.1 4 0 0 4 4 4 0 HEAT-like repeat DUF4611 PF15387.6 KXT03276.1 - 3.5 7.9 8.9 29 5.0 2.1 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Fungal_trans PF04082.18 KXT03277.1 - 4e-42 144.1 0.0 6.6e-42 143.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT03277.1 - 6.3e-09 35.8 8.1 1.4e-08 34.7 8.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lipin_mid PF16876.5 KXT03277.1 - 0.072 13.2 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Lipin/Ned1/Smp2 multi-domain protein middle domain Fungal_trans PF04082.18 KXT03278.1 - 4e-42 144.1 0.0 6.6e-42 143.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT03278.1 - 6.3e-09 35.8 8.1 1.4e-08 34.7 8.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lipin_mid PF16876.5 KXT03278.1 - 0.072 13.2 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Lipin/Ned1/Smp2 multi-domain protein middle domain Fungal_trans PF04082.18 KXT03279.1 - 4e-42 144.1 0.0 6.6e-42 143.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT03279.1 - 6.3e-09 35.8 8.1 1.4e-08 34.7 8.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lipin_mid PF16876.5 KXT03279.1 - 0.072 13.2 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Lipin/Ned1/Smp2 multi-domain protein middle domain Metallophos PF00149.28 KXT03283.1 - 2.5e-35 122.8 0.2 3.2e-35 122.5 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KXT03283.1 - 0.033 14.6 0.2 0.086 13.3 0.2 1.8 1 1 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 KXT03283.1 - 0.069 13.3 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain RNase_PH PF01138.21 KXT03284.1 - 2.2e-27 96.1 0.0 4.9e-27 95.0 0.0 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH PF01138.21 KXT03285.1 - 2.4e-27 96.1 0.0 5.1e-27 95.0 0.0 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 GILT PF03227.16 KXT03286.1 - 2.4e-20 72.7 0.4 4.7e-20 71.8 0.0 1.7 2 0 0 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Myb_Cef PF11831.8 KXT03287.1 - 1.7e-41 142.4 3.5 1.7e-41 142.4 3.5 2.9 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 KXT03287.1 - 1.9e-22 79.2 4.4 1.8e-11 44.0 0.7 3.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXT03287.1 - 2.8e-20 72.3 4.7 1.4e-13 50.9 1.3 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 KXT03287.1 - 0.00022 21.2 0.1 0.0033 17.5 0.0 2.9 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain HAD PF12710.7 KXT03288.1 - 1.1e-25 91.2 0.0 1.4e-25 90.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KXT03288.1 - 5.1e-05 22.8 0.0 0.00024 20.6 0.0 1.8 1 1 0 1 1 1 1 Putative Phosphatase UMPH-1 PF05822.12 KXT03288.1 - 0.0012 18.4 0.0 0.01 15.4 0.0 2.2 2 1 1 3 3 3 1 Pyrimidine 5'-nucleotidase (UMPH-1) P3A PF08727.11 KXT03288.1 - 0.15 11.5 0.0 9.1 5.7 0.0 2.3 2 0 0 2 2 2 0 Poliovirus 3A protein like Cu-oxidase_3 PF07732.15 KXT03289.1 - 5.3e-39 132.9 5.2 7.7e-39 132.4 1.7 2.9 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KXT03289.1 - 1.8e-38 131.4 6.0 5.7e-37 126.5 0.1 3.2 2 2 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 KXT03289.1 - 1.4e-31 109.7 0.1 1.1e-29 103.6 0.0 2.9 3 0 0 3 3 3 1 Multicopper oxidase Aminotran_1_2 PF00155.21 KXT03290.1 - 3.1e-16 59.5 0.0 4e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Glyco_hydro_72 PF03198.14 KXT03291.1 - 3.1e-117 391.3 0.1 3.9e-117 391.0 0.1 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.17 KXT03291.1 - 1.5e-05 24.3 0.1 2.8e-05 23.4 0.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.18 KXT03291.1 - 0.0003 20.3 0.1 0.0023 17.4 0.1 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) ATP_bind_3 PF01171.20 KXT03292.1 - 1e-37 129.7 0.0 1.6e-37 129.1 0.0 1.3 1 0 0 1 1 1 1 PP-loop family ATP_bind_3 PF01171.20 KXT03293.1 - 1e-37 129.7 0.0 1.6e-37 129.1 0.0 1.3 1 0 0 1 1 1 1 PP-loop family ATP_bind_3 PF01171.20 KXT03295.1 - 1e-37 129.7 0.0 1.6e-37 129.1 0.0 1.3 1 0 0 1 1 1 1 PP-loop family Glyco_hydro_125 PF06824.11 KXT03296.1 - 8.8e-182 604.6 0.0 1e-181 604.4 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) TPP_enzyme_N PF02776.18 KXT03297.1 - 1.8e-30 105.8 0.5 3.7e-30 104.8 0.5 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KXT03297.1 - 1.6e-18 66.7 0.0 1e-17 64.2 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KXT03297.1 - 3.1e-16 59.5 0.0 1.4e-15 57.4 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Pyr_redox_2 PF07992.14 KXT03298.1 - 5.4e-12 45.5 0.0 3e-11 43.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXT03298.1 - 2.6e-10 40.1 0.0 5.1e-07 29.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KXT03298.1 - 3.8e-10 38.8 0.0 8.1e-10 37.7 0.0 1.4 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KXT03298.1 - 3.1e-08 33.7 0.0 9.5e-05 22.6 0.0 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KXT03298.1 - 5.2e-06 25.8 0.0 5.8e-05 22.4 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KXT03298.1 - 0.00046 20.7 0.0 0.034 14.7 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXT03298.1 - 0.0028 16.8 0.0 0.057 12.5 0.0 2.7 2 1 0 2 2 2 1 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 KXT03298.1 - 0.019 14.3 0.0 0.042 13.2 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 KXT03298.1 - 0.023 14.7 0.0 2 8.4 0.0 2.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 KXT03298.1 - 0.047 13.0 0.0 6.8 5.9 0.0 2.8 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 KXT03298.1 - 0.06 13.4 0.0 0.59 10.2 0.0 2.3 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 KXT03298.1 - 0.071 13.5 0.0 0.75 10.3 0.0 2.5 3 1 0 3 3 3 0 Putative NAD(P)-binding zf-HIT PF04438.16 KXT03299.1 - 2.5e-08 33.6 12.7 3.8e-08 33.0 12.7 1.3 1 0 0 1 1 1 1 HIT zinc finger AAA_6 PF12774.7 KXT03300.1 - 2.2e-124 414.7 0.2 1.6e-122 408.6 0.0 3.4 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KXT03300.1 - 1.6e-121 406.1 5.4 1.6e-121 406.1 5.4 5.1 7 0 0 7 7 4 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 KXT03300.1 - 4.5e-108 362.3 1.9 4.5e-108 362.3 1.9 5.2 6 0 0 6 6 6 1 Dynein heavy chain, N-terminal region 1 AAA_9 PF12781.7 KXT03300.1 - 2.4e-73 245.9 0.2 2.4e-73 245.9 0.2 5.3 7 1 1 8 8 6 1 ATP-binding dynein motor region AAA_8 PF12780.7 KXT03300.1 - 4.1e-66 223.0 0.0 3.1e-65 220.1 0.0 2.7 3 0 0 3 3 2 1 P-loop containing dynein motor region D4 MT PF12777.7 KXT03300.1 - 4.7e-38 131.1 7.3 1.2e-37 129.7 7.3 1.7 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.7 KXT03300.1 - 1.2e-33 116.1 0.0 2.6e-27 95.5 0.0 4.4 4 0 0 4 4 4 2 P-loop containing dynein motor region Dynein_heavy PF03028.15 KXT03300.1 - 3.8e-28 98.0 0.0 8.2e-27 93.7 0.0 3.1 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 KXT03300.1 - 1.7e-27 96.1 0.1 9.6e-12 45.1 0.0 6.2 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_lid_11 PF18198.1 KXT03300.1 - 8e-26 90.8 0.0 1.8e-25 89.6 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain HR1 PF02185.16 KXT03300.1 - 2.3e-20 72.5 13.3 7e-12 45.3 3.5 6.9 6 1 1 7 7 5 2 Hr1 repeat C1_1 PF00130.22 KXT03300.1 - 6.2e-19 67.6 30.4 3.7e-11 42.7 9.2 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Dynein_AAA_lid PF17852.1 KXT03300.1 - 4.7e-17 62.3 5.5 1.5e-16 60.6 0.0 4.0 4 0 0 4 4 3 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 KXT03300.1 - 7.5e-16 58.6 4.1 0.0084 16.4 0.0 8.2 7 0 0 7 7 7 3 AAA domain AAA PF00004.29 KXT03300.1 - 1.1e-12 48.5 0.0 0.015 15.7 0.0 5.4 5 0 0 5 5 4 3 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KXT03300.1 - 4.4e-11 43.1 0.5 0.022 14.9 0.0 5.2 4 0 0 4 4 4 3 AAA domain T2SSE PF00437.20 KXT03300.1 - 2.1e-08 33.6 0.0 0.0088 15.1 0.0 3.7 3 0 0 3 3 3 3 Type II/IV secretion system protein AAA_18 PF13238.6 KXT03300.1 - 7.7e-08 33.0 5.5 0.15 12.6 0.0 5.9 5 0 0 5 5 4 2 AAA domain AAA_16 PF13191.6 KXT03300.1 - 1e-07 32.5 7.5 2.1 8.7 0.0 8.1 7 0 0 7 7 5 2 AAA ATPase domain C2 PF00168.30 KXT03300.1 - 4.8e-06 26.8 0.0 1.3e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 C2 domain FtsK_SpoIIIE PF01580.18 KXT03300.1 - 6e-06 25.8 0.0 0.86 8.9 0.1 4.3 3 0 0 3 3 3 2 FtsK/SpoIIIE family AAA_30 PF13604.6 KXT03300.1 - 6.1e-05 22.8 0.5 26 4.4 0.0 5.4 5 0 0 5 5 5 0 AAA domain AAA_29 PF13555.6 KXT03300.1 - 6.3e-05 22.6 0.2 2.7 7.8 0.0 3.6 3 0 0 3 3 3 2 P-loop containing region of AAA domain Mg_chelatase PF01078.21 KXT03300.1 - 6.8e-05 22.3 1.0 0.74 9.2 0.0 3.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 KXT03300.1 - 7.4e-05 23.3 0.1 6.3 7.3 0.0 5.1 3 0 0 3 3 3 0 ABC transporter AAA_24 PF13479.6 KXT03300.1 - 9.3e-05 22.2 2.4 7.5 6.2 0.0 5.7 5 0 0 5 5 5 0 AAA domain AAA_lid_1 PF17857.1 KXT03300.1 - 0.00013 22.1 0.0 0.0022 18.2 0.0 2.9 2 0 0 2 2 2 1 AAA+ lid domain AAA_19 PF13245.6 KXT03300.1 - 0.00072 19.9 4.3 0.3 11.4 0.0 5.0 5 0 0 5 5 4 1 AAA domain IstB_IS21 PF01695.17 KXT03300.1 - 0.0021 17.8 0.2 1.6 8.5 0.0 4.8 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_25 PF13481.6 KXT03300.1 - 0.0023 17.5 0.2 1.2 8.7 0.0 4.7 4 0 0 4 4 4 1 AAA domain RNA_helicase PF00910.22 KXT03300.1 - 0.0032 17.8 0.2 4.7 7.6 0.0 4.5 4 0 0 4 4 4 0 RNA helicase Rad17 PF03215.15 KXT03300.1 - 0.0043 17.0 0.3 7.3 6.5 0.0 4.3 4 0 0 4 4 3 0 Rad17 P-loop domain RsgA_GTPase PF03193.16 KXT03300.1 - 0.014 15.3 0.0 6.7 6.6 0.0 3.6 4 0 0 4 4 3 0 RsgA GTPase G-gamma PF00631.22 KXT03300.1 - 0.063 13.3 1.1 0.52 10.4 0.0 3.3 3 0 0 3 3 1 0 GGL domain Vps23_core PF09454.10 KXT03300.1 - 0.49 10.4 2.6 52 3.9 0.0 3.9 3 0 0 3 3 2 0 Vps23 core domain AAA_11 PF13086.6 KXT03300.1 - 0.88 9.3 0.0 0.88 9.3 0.0 5.3 5 0 0 5 5 4 0 AAA domain WXG100 PF06013.12 KXT03300.1 - 1.3 9.3 9.7 2.4 8.4 3.0 5.4 3 0 0 3 3 2 0 Proteins of 100 residues with WXG SRP54 PF00448.22 KXT03300.1 - 2.8 7.5 4.8 29 4.2 0.1 3.7 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain DUF948 PF06103.11 KXT03300.1 - 7.9 6.8 10.9 7.6 6.9 0.2 5.9 4 0 0 4 4 3 0 Bacterial protein of unknown function (DUF948) Rad60-SLD_2 PF13881.6 KXT03301.1 - 5.4e-11 42.6 0.0 8.6e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KXT03301.1 - 0.0028 17.4 0.0 0.0049 16.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 KXT03301.1 - 0.07 13.7 0.0 0.12 13.0 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Acyl_transf_3 PF01757.22 KXT03302.1 - 2.5e-18 66.3 33.6 5.1e-18 65.2 33.6 1.6 1 1 0 1 1 1 1 Acyltransferase family Phage_holin_3_6 PF07332.11 KXT03302.1 - 8.4 6.5 9.9 13 5.9 6.7 2.9 2 1 1 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Pyrid_ox_like PF16242.5 KXT03303.1 - 6.2e-23 81.0 0.0 9.5e-23 80.4 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 KXT03303.1 - 1.3e-08 34.9 0.0 1.9e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF3248 PF11609.8 KXT03303.1 - 0.071 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3248) Ribosomal_L23 PF00276.20 KXT03310.1 - 1.5e-06 28.4 0.0 2.9e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 Ribosomal_L23 PF00276.20 KXT03312.1 - 5.9e-06 26.6 0.0 1.2e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 Adeno_GP19K PF04881.13 KXT03313.1 - 0.07 13.1 0.2 1.5 8.8 0.0 2.3 2 0 0 2 2 2 0 Adenovirus GP19K FAD_binding_3 PF01494.19 KXT03314.1 - 2.2e-21 76.5 0.0 2.3e-20 73.1 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 KXT03314.1 - 0.00038 19.6 0.0 0.56 9.2 0.0 2.2 2 0 0 2 2 2 2 Squalene epoxidase NAD_binding_8 PF13450.6 KXT03314.1 - 0.0021 18.2 0.2 0.0094 16.2 0.2 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXT03314.1 - 0.0061 15.8 0.2 0.089 12.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXT03314.1 - 0.01 15.5 0.1 0.18 11.4 0.2 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXT03314.1 - 0.017 14.4 0.1 0.27 10.4 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXT03314.1 - 0.067 13.8 0.4 0.19 12.3 0.2 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase p450 PF00067.22 KXT03315.1 - 8.6e-78 262.1 0.0 1.1e-77 261.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Metallophos PF00149.28 KXT03316.1 - 2.1e-34 119.8 0.0 1.3e-29 104.2 0.0 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 KXT03316.1 - 0.0091 15.7 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain RNase_PH_C PF03725.15 KXT03319.1 - 0.16 12.0 0.1 0.32 11.1 0.1 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 FAD_binding_1 PF00667.20 KXT03320.1 - 1e-63 214.9 0.0 1.5e-63 214.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KXT03320.1 - 2.1e-34 118.8 3.0 2.5e-34 118.5 1.0 2.1 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 KXT03320.1 - 2.3e-21 76.5 0.1 1.8e-20 73.6 0.1 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Bromodomain PF00439.25 KXT03320.1 - 0.14 12.3 0.0 0.41 10.7 0.0 2.0 1 0 0 1 1 1 0 Bromodomain adh_short_C2 PF13561.6 KXT03321.1 - 2.2e-44 151.8 0.0 3e-44 151.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXT03321.1 - 5.4e-36 123.9 0.1 7.1e-36 123.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXT03321.1 - 3.5e-07 30.3 0.0 4.4e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXT03321.1 - 1.8e-05 24.0 0.0 2.6e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KXT03321.1 - 2.5e-05 23.9 0.0 7.1e-05 22.4 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KXT03321.1 - 0.0024 17.3 0.0 0.023 14.1 0.0 2.0 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_7 PF13241.6 KXT03321.1 - 0.0058 17.1 0.0 0.0099 16.3 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding GDP_Man_Dehyd PF16363.5 KXT03321.1 - 0.0068 15.8 0.0 0.0089 15.5 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase THF_DHG_CYH_C PF02882.19 KXT03321.1 - 0.014 14.7 0.0 0.034 13.4 0.0 1.7 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RmlD_sub_bind PF04321.17 KXT03321.1 - 0.081 12.0 0.0 0.17 11.0 0.0 1.6 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_10 PF13460.6 KXT03321.1 - 0.11 12.4 0.1 0.41 10.5 0.0 1.9 1 1 1 2 2 2 0 NAD(P)H-binding IBN_N PF03810.19 KXT03322.1 - 7.2e-12 45.1 1.9 3.5e-11 42.9 0.3 3.0 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KXT03322.1 - 3.7e-07 30.3 2.9 0.00091 19.3 0.0 3.9 5 0 0 5 5 5 2 Exportin 1-like protein RIX1 PF08167.12 KXT03322.1 - 4.3e-05 23.3 0.1 0.00045 20.0 0.1 2.5 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis CAS_CSE1 PF03378.15 KXT03322.1 - 0.012 14.2 0.0 0.026 13.0 0.0 1.6 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus HEAT_EZ PF13513.6 KXT03322.1 - 0.016 15.7 5.5 9.2 6.9 0.7 5.8 5 1 1 6 6 6 0 HEAT-like repeat ZZ PF00569.17 KXT03323.1 - 1.3e-08 34.6 9.0 1.3e-08 34.6 9.0 1.9 2 0 0 2 2 2 1 Zinc finger, ZZ type MFS_1 PF07690.16 KXT03324.1 - 5.2e-49 167.0 12.9 2e-44 152.0 11.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXT03324.1 - 5.9e-05 21.8 14.4 0.032 12.8 0.2 2.9 3 1 0 3 3 3 2 MFS/sugar transport protein Sugar_tr PF00083.24 KXT03324.1 - 7.6e-05 21.8 21.5 0.0038 16.1 10.4 3.5 2 2 1 3 3 3 3 Sugar (and other) transporter BT1 PF03092.16 KXT03324.1 - 0.00012 20.5 0.2 0.52 8.5 0.0 3.0 3 0 0 3 3 3 2 BT1 family OATP PF03137.20 KXT03324.1 - 0.003 15.9 5.2 0.32 9.2 1.7 2.3 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 KXT03324.1 - 0.038 12.9 10.4 0.52 9.1 7.2 2.8 2 1 1 3 3 3 0 MFS_1 like family Sec1 PF00995.23 KXT03325.1 - 1.1e-115 388.1 0.0 1.2e-115 387.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF4913 PF16259.5 KXT03326.1 - 0.022 14.8 0.2 0.04 14.0 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4913) CoA_transf_3 PF02515.17 KXT03328.1 - 7.3e-119 397.2 0.0 2.9e-118 395.2 0.0 1.7 1 1 0 1 1 1 1 CoA-transferase family III Acyl-CoA_dh_1 PF00441.24 KXT03329.1 - 2.7e-37 128.3 2.8 5e-37 127.4 2.8 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KXT03329.1 - 2e-23 83.2 0.0 4.4e-23 82.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KXT03329.1 - 2.9e-16 59.4 0.0 5.3e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KXT03329.1 - 1.9e-14 54.0 0.5 3.9e-14 53.1 0.5 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_1 PF00441.24 KXT03330.1 - 2.7e-37 128.3 2.8 5e-37 127.4 2.8 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KXT03330.1 - 2e-23 83.2 0.0 4.4e-23 82.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KXT03330.1 - 2.9e-16 59.4 0.0 5.3e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KXT03330.1 - 1.9e-14 54.0 0.5 3.9e-14 53.1 0.5 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Glyco_hydro_18 PF00704.28 KXT03331.1 - 4.8e-38 131.6 0.0 6.4e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 KXT03331.1 - 5.7e-10 39.1 0.0 0.00037 20.5 0.0 2.5 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.19 KXT03331.1 - 1.2e-05 25.7 8.5 1.2e-05 25.7 8.5 3.6 3 1 0 3 3 3 1 Chitin recognition protein AbrB PF05145.12 KXT03331.1 - 0.053 12.5 0.0 0.074 12.0 0.0 1.1 1 0 0 1 1 1 0 Transition state regulatory protein AbrB Cytomega_gL PF01801.16 KXT03332.1 - 0.0044 16.5 0.0 0.0061 16.0 0.0 1.2 1 0 0 1 1 1 1 Cytomegalovirus glycoprotein L TAP42 PF04177.12 KXT03334.1 - 2.7e-105 352.0 6.2 3.1e-105 351.8 6.2 1.0 1 0 0 1 1 1 1 TAP42-like family E2F_CC-MB PF16421.5 KXT03334.1 - 0.0058 17.0 1.8 0.014 15.7 0.1 2.3 2 0 0 2 2 2 1 E2F transcription factor CC-MB domain Glyco_trans_1_2 PF13524.6 KXT03334.1 - 0.0077 16.6 0.8 1.6 9.1 0.1 2.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 PilJ PF13675.6 KXT03334.1 - 0.051 13.6 0.8 0.13 12.3 0.3 1.9 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Streptin-Immun PF11083.8 KXT03334.1 - 0.085 13.3 2.1 3.9 8.0 0.3 2.6 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein DASH_Duo1 PF08651.10 KXT03334.1 - 0.098 12.4 0.2 0.28 11.0 0.2 1.8 1 0 0 1 1 1 0 DASH complex subunit Duo1 VF530 PF09905.9 KXT03334.1 - 0.17 12.1 0.4 0.39 10.9 0.1 1.7 2 0 0 2 2 2 0 DNA-binding protein VF530 PACT_coil_coil PF10495.9 KXT03334.1 - 0.65 10.6 3.6 14 6.4 0.0 2.7 2 0 0 2 2 2 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein Haemagg_act PF05860.13 KXT03335.1 - 0.18 11.7 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 haemagglutination activity domain HTH_48 PF17906.1 KXT03335.1 - 0.19 11.9 0.3 0.4 10.8 0.3 1.5 1 0 0 1 1 1 0 HTH domain in Mos1 transposase Oxidored_FMN PF00724.20 KXT03336.1 - 1.2e-60 205.6 0.0 4.3e-58 197.2 0.0 2.2 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family CLP1_P PF16575.5 KXT03337.1 - 5.2e-34 117.7 0.0 8.1e-34 117.1 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 KXT03337.1 - 2e-29 101.6 0.0 3.6e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 KXT03337.1 - 5.1e-23 81.7 0.0 9.7e-23 80.8 0.0 1.5 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 ATP_bind_1 PF03029.17 KXT03337.1 - 0.00016 21.5 0.0 0.00036 20.4 0.0 1.6 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 KXT03337.1 - 0.0066 16.5 0.4 0.24 11.5 0.0 2.2 2 0 0 2 2 2 1 Dynamin family AAA_16 PF13191.6 KXT03337.1 - 0.013 15.9 0.0 0.027 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 KXT03337.1 - 0.013 15.5 0.0 1.8 8.7 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXT03337.1 - 0.087 12.7 0.0 6.5 6.6 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase Ribonuclease_3 PF00636.26 KXT03338.1 - 1.8e-42 144.2 0.0 1.8e-20 73.5 0.0 2.8 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KXT03338.1 - 5.9e-23 81.4 0.2 4.3e-10 39.8 0.0 4.1 2 2 0 2 2 2 2 Ribonuclease-III-like Dicer_dimer PF03368.14 KXT03338.1 - 2.8e-22 78.7 0.0 1.5e-21 76.4 0.0 2.2 2 0 0 2 2 2 1 Dicer dimerisation domain Helicase_C PF00271.31 KXT03338.1 - 5.9e-16 58.8 0.1 1.5e-15 57.5 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXT03338.1 - 3.1e-13 50.1 0.2 8.5e-13 48.6 0.2 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KXT03338.1 - 1.8e-12 47.4 0.0 3.4e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase dsrm PF00035.26 KXT03338.1 - 0.0052 17.5 0.0 1.9 9.2 0.0 3.0 2 0 0 2 2 2 1 Double-stranded RNA binding motif SWI2_SNF2 PF18766.1 KXT03338.1 - 0.0074 16.0 0.0 0.038 13.6 0.0 2.2 1 1 0 1 1 1 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 KXT03338.1 - 0.063 13.6 0.2 0.42 10.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Abhydrolase_1 PF00561.20 KXT03339.1 - 6.3e-07 29.3 0.1 1.7e-06 27.9 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXT03339.1 - 3.4e-05 24.6 0.6 3.4e-05 24.6 0.6 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXT03339.1 - 0.005 16.1 0.0 0.021 14.1 0.0 2.1 2 1 0 2 2 2 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 KXT03339.1 - 0.0066 16.2 0.4 0.014 15.1 0.4 1.5 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.13 KXT03339.1 - 0.014 15.3 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 KXT03339.1 - 0.026 14.4 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Chlorophyllase2 PF12740.7 KXT03339.1 - 0.027 13.4 0.2 0.19 10.6 0.0 2.1 2 0 0 2 2 2 0 Chlorophyllase enzyme Lipase_3 PF01764.25 KXT03339.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_1 PF00561.20 KXT03340.1 - 6.4e-07 29.3 0.1 1.7e-06 27.9 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXT03340.1 - 3.3e-05 24.6 0.7 3.3e-05 24.6 0.7 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXT03340.1 - 0.005 16.1 0.0 0.021 14.1 0.0 2.1 2 1 0 2 2 2 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 KXT03340.1 - 0.0065 16.2 0.4 0.014 15.1 0.4 1.5 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.13 KXT03340.1 - 0.014 15.3 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 KXT03340.1 - 0.026 14.4 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Chlorophyllase2 PF12740.7 KXT03340.1 - 0.028 13.3 0.2 0.19 10.6 0.0 2.1 2 0 0 2 2 2 0 Chlorophyllase enzyme Lipase_3 PF01764.25 KXT03340.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Glyco_hydro_18 PF00704.28 KXT03341.1 - 5e-16 59.3 0.0 1.7e-15 57.6 0.0 2.0 2 1 1 3 3 3 1 Glycosyl hydrolases family 18 Abhydrolase_1 PF00561.20 KXT03342.1 - 6.4e-07 29.3 0.1 1.7e-06 27.9 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXT03342.1 - 3.3e-05 24.6 0.7 3.3e-05 24.6 0.7 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXT03342.1 - 0.005 16.1 0.0 0.021 14.1 0.0 2.1 2 1 0 2 2 2 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 KXT03342.1 - 0.0065 16.2 0.4 0.014 15.1 0.4 1.5 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.13 KXT03342.1 - 0.014 15.3 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 KXT03342.1 - 0.026 14.4 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Chlorophyllase2 PF12740.7 KXT03342.1 - 0.028 13.3 0.2 0.19 10.6 0.0 2.1 2 0 0 2 2 2 0 Chlorophyllase enzyme Lipase_3 PF01764.25 KXT03342.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Glyco_hydro_18 PF00704.28 KXT03343.1 - 5e-16 59.3 0.0 1.7e-15 57.6 0.0 2.0 2 1 1 3 3 3 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.28 KXT03344.1 - 5.1e-16 59.3 0.0 1.7e-15 57.6 0.0 1.9 2 1 1 3 3 3 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.28 KXT03345.1 - 5.1e-16 59.3 0.0 1.7e-15 57.6 0.0 1.9 2 1 1 3 3 3 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.28 KXT03346.1 - 5e-16 59.3 0.0 1.7e-15 57.6 0.0 2.0 2 1 1 3 3 3 1 Glycosyl hydrolases family 18 PQ-loop PF04193.14 KXT03348.1 - 2.4e-18 65.7 6.5 1e-10 41.2 0.5 3.4 4 0 0 4 4 4 2 PQ loop repeat ER_lumen_recept PF00810.18 KXT03348.1 - 0.0019 19.1 0.8 0.005 17.7 0.1 2.0 1 1 1 2 2 2 1 ER lumen protein retaining receptor DUF2681 PF10883.8 KXT03348.1 - 1.9 9.0 0.0 1.9 9.0 0.0 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2681) ABC2_membrane_5 PF13346.6 KXT03348.1 - 4.8 6.7 15.6 3 7.3 9.5 2.7 3 0 0 3 3 3 0 ABC-2 family transporter protein WD40 PF00400.32 KXT03350.1 - 1.8e-10 41.2 10.1 0.13 13.1 0.0 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXT03350.1 - 0.00052 20.3 0.4 0.4 11.0 0.0 4.2 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_FG PF13634.6 KXT03351.1 - 4.7e-13 49.8 65.5 5.9e-06 27.0 21.7 3.4 1 1 1 2 2 2 2 Nucleoporin FG repeat region Spc7 PF08317.11 KXT03351.1 - 0.04 12.8 4.1 0.024 13.6 2.0 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein Atg14 PF10186.9 KXT03351.1 - 0.057 12.5 1.6 0.097 11.7 1.6 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Laminin_II PF06009.12 KXT03351.1 - 0.072 13.1 4.0 0.18 11.8 2.0 2.2 2 0 0 2 2 2 0 Laminin Domain II FH2 PF02181.23 KXT03351.1 - 0.11 11.6 1.8 0.21 10.7 1.8 1.4 1 0 0 1 1 1 0 Formin Homology 2 Domain STAT_alpha PF01017.20 KXT03351.1 - 0.3 10.9 5.2 0.75 9.7 3.1 2.2 2 0 0 2 2 2 0 STAT protein, all-alpha domain DUF16 PF01519.16 KXT03351.1 - 0.35 11.4 7.1 0.28 11.7 3.3 2.3 2 1 0 2 2 2 0 Protein of unknown function DUF16 XhlA PF10779.9 KXT03351.1 - 0.42 10.9 3.4 0.92 9.8 3.4 1.6 1 0 0 1 1 1 0 Haemolysin XhlA DUF1664 PF07889.12 KXT03351.1 - 0.6 10.2 4.6 0.37 10.8 1.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF724 PF05266.14 KXT03351.1 - 0.63 9.8 6.1 0.3 10.9 3.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF745 PF05335.13 KXT03351.1 - 0.81 9.4 6.8 0.13 12.0 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) CHASE3 PF05227.13 KXT03351.1 - 1 9.3 6.3 0.29 11.0 2.1 2.2 2 1 0 2 2 2 0 CHASE3 domain FlaC_arch PF05377.11 KXT03351.1 - 1.3 9.5 4.7 9 6.8 0.1 3.3 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) TMPIT PF07851.13 KXT03351.1 - 2.6 7.2 3.5 2 7.6 0.8 2.0 2 1 1 3 3 3 0 TMPIT-like protein Fib_alpha PF08702.10 KXT03351.1 - 6.9 6.8 6.9 5 7.3 1.4 2.6 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family MatE PF01554.18 KXT03352.1 - 6.6e-60 201.4 23.5 1.9e-36 125.1 8.1 2.4 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KXT03352.1 - 3.3e-05 24.0 11.3 3.3e-05 24.0 11.3 3.2 5 0 0 5 5 5 2 Polysaccharide biosynthesis C-terminal domain Ribosomal_L26 PF16906.5 KXT03353.1 - 7.3e-37 125.7 4.1 1.2e-36 125.0 4.1 1.4 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 KXT03353.1 - 4.2e-07 29.7 0.4 8.9e-07 28.7 0.4 1.6 1 0 0 1 1 1 1 KOW motif DUF1223 PF06764.11 KXT03353.1 - 0.022 14.8 0.1 0.031 14.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) XAP5 PF04921.14 KXT03354.1 - 1.9e-83 280.2 0.5 2.9e-83 279.6 0.5 1.2 1 0 0 1 1 1 1 XAP5, circadian clock regulator ORC6 PF05460.13 KXT03354.1 - 3.8 6.7 12.4 0.82 8.9 6.3 2.1 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) FAD_binding_4 PF01565.23 KXT03356.1 - 1.3e-25 89.8 0.2 2.2e-25 89.0 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXT03356.1 - 1.4e-11 44.3 0.1 2.6e-11 43.5 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like HORMA PF02301.18 KXT03357.1 - 3.8e-10 39.7 0.0 5.1e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 HORMA domain TPR_1 PF00515.28 KXT03358.1 - 3.4e-07 29.8 0.0 0.0051 16.6 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXT03358.1 - 2.4e-05 23.9 0.3 7e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.17 KXT03358.1 - 2.7e-05 23.9 0.1 0.11 12.6 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXT03358.1 - 0.00047 20.6 0.1 0.0014 19.1 0.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXT03358.1 - 0.0065 16.7 0.6 0.018 15.3 0.2 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF5315 PF17242.2 KXT03358.1 - 0.032 14.0 0.7 0.086 12.7 0.7 1.7 1 0 0 1 1 1 0 Disordered region of unknown function (DUF5315) TPR_7 PF13176.6 KXT03358.1 - 0.09 12.8 0.0 3.1 8.0 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF5113 PF17140.4 KXT03358.1 - 0.15 11.8 0.1 0.34 10.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5113) AATF-Che1 PF13339.6 KXT03358.1 - 0.16 12.6 2.4 0.34 11.6 1.4 1.9 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Glyco_hydro_92 PF07971.12 KXT03360.1 - 0.042 12.8 0.0 0.049 12.6 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 92 SprT-like PF10263.9 KXT03361.1 - 0.0014 18.4 0.2 0.0038 17.1 0.2 1.7 1 1 0 1 1 1 1 SprT-like family NUT PF12881.7 KXT03361.1 - 6.9 5.0 5.2 8.9 4.6 5.2 1.1 1 0 0 1 1 1 0 NUT protein Cyclase PF04199.13 KXT03362.1 - 2.4e-11 44.0 0.0 4.4e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Putative cyclase RRM_1 PF00076.22 KXT03363.1 - 7.8e-25 86.5 0.1 2.9e-11 43.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KXT03363.1 - 0.0023 17.9 1.1 0.0046 17.0 1.1 1.5 1 0 0 1 1 1 1 RNA binding motif RRM_5 PF13893.6 KXT03363.1 - 0.008 15.8 0.0 0.49 10.0 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXT03363.1 - 0.016 15.1 0.0 0.15 11.9 0.0 2.1 2 0 0 2 2 2 0 Occluded RNA-recognition motif Limkain-b1 PF11608.8 KXT03363.1 - 0.077 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Limkain b1 Ammonium_transp PF00909.21 KXT03364.1 - 7.2e-112 374.0 21.2 8.6e-112 373.7 21.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family HET PF06985.11 KXT03365.1 - 1.8e-05 25.1 0.0 2.9e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) UvrB_inter PF17757.1 KXT03365.1 - 0.14 12.3 0.0 3.1 8.1 0.0 2.5 3 0 0 3 3 3 0 UvrB interaction domain PAPS_reduct PF01507.19 KXT03368.1 - 1e-27 97.3 0.0 5.4e-19 68.9 0.0 2.3 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family MHB PF16525.5 KXT03368.1 - 0.075 13.3 0.0 0.78 10.0 0.0 2.3 2 0 0 2 2 2 0 Haemophore, haem-binding UNC45-central PF11701.8 KXT03370.1 - 3.3e-45 153.8 4.2 2.1e-44 151.2 0.5 3.6 3 0 0 3 3 3 1 Myosin-binding striated muscle assembly central MIT PF04212.18 KXT03370.1 - 0.065 13.3 0.4 32 4.7 0.1 3.9 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_14 PF13428.6 KXT03370.1 - 0.42 11.6 4.0 2 9.4 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2497 PF10691.9 KXT03370.1 - 3.1 8.3 6.1 5.5 7.5 0.2 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2497) TRIQK PF15168.6 KXT03371.1 - 7.3 6.6 5.6 2.1 8.3 0.0 2.7 3 0 0 3 3 3 0 Triple QxxK/R motif-containing protein family MRAP PF15183.6 KXT03371.1 - 7.5 6.6 10.4 0.72 9.8 0.5 2.9 2 1 1 3 3 3 0 Melanocortin-2 receptor accessory protein family ECH_1 PF00378.20 KXT03372.1 - 4.2e-40 137.6 0.0 2e-39 135.4 0.0 1.8 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXT03372.1 - 2.8e-23 82.9 0.0 1.4e-22 80.7 0.0 2.2 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase Glyco_hydro_47 PF01532.20 KXT03373.1 - 2.8e-108 362.8 0.0 3.2e-108 362.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 RRM_1 PF00076.22 KXT03374.1 - 1.1e-28 98.9 0.0 2.9e-14 52.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 KXT03374.1 - 0.0042 17.3 0.0 0.0076 16.5 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 MOR2-PAG1_N PF14222.6 KXT03375.1 - 1.6e-204 680.9 0.0 2.4e-204 680.3 0.0 1.3 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 KXT03375.1 - 2.3e-97 325.8 0.3 5.9e-97 324.5 0.3 1.8 1 0 0 1 1 1 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 KXT03375.1 - 1.1e-36 125.9 6.7 7.4e-13 47.1 0.0 4.2 3 1 1 4 4 4 4 Cell morphogenesis central region DUF2009 PF09418.10 KXT03375.1 - 0.036 13.1 0.0 0.067 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) TAN PF11640.8 KXT03375.1 - 0.34 11.0 3.9 0.36 11.0 0.9 2.6 1 1 1 2 2 2 0 Telomere-length maintenance and DNA damage repair F-box-like PF12937.7 KXT03376.1 - 0.002 17.9 0.0 0.002 17.9 0.0 2.3 3 1 0 3 3 3 1 F-box-like DUF4385 PF14328.6 KXT03377.1 - 7.7e-53 178.5 1.3 7.7e-53 178.5 1.3 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4385) LRR_8 PF13855.6 KXT03378.1 - 3.4e-07 29.9 15.1 8.5e-05 22.2 0.2 3.8 3 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 KXT03378.1 - 0.00018 21.8 15.7 0.091 13.2 0.1 5.0 1 1 6 7 7 7 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXT03378.1 - 0.0012 19.1 11.2 11 7.1 0.3 6.1 6 0 0 6 6 6 2 Leucine Rich Repeat LRRNT_2 PF08263.12 KXT03378.1 - 0.002 18.4 0.4 0.0093 16.2 0.1 2.3 2 1 0 2 2 2 1 Leucine rich repeat N-terminal domain Aminotran_4 PF01063.19 KXT03378.1 - 0.053 13.4 0.1 0.22 11.3 0.1 1.8 2 0 0 2 2 2 0 Amino-transferase class IV SUV3_C PF12513.8 KXT03379.1 - 4.1e-17 61.8 0.0 1.1e-16 60.5 0.0 1.8 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 KXT03379.1 - 1.8e-09 38.0 0.0 5.1e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Suv3_C_1 PF18147.1 KXT03379.1 - 0.001 18.9 0.0 0.0024 17.7 0.0 1.6 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 DUF3328 PF11807.8 KXT03380.1 - 3.5e-41 141.4 0.6 5e-41 140.9 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) MMS1_N PF10433.9 KXT03383.1 - 4e-129 431.4 0.0 6.4e-129 430.7 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KXT03383.1 - 1.8e-76 257.5 0.0 1.2e-75 254.8 0.0 2.3 3 0 0 3 3 3 1 CPSF A subunit region HPS3_N PF14761.6 KXT03383.1 - 0.04 13.4 0.3 7.3 6.1 0.1 4.2 4 1 1 5 5 5 0 Hermansky-Pudlak syndrome 3 Sin_N PF04801.13 KXT03385.1 - 7.7e-33 114.3 3.0 6.9e-32 111.2 3.0 1.9 1 1 0 1 1 1 1 Sin-like protein conserved region Sin_N PF04801.13 KXT03386.1 - 7.7e-33 114.3 3.0 6.9e-32 111.2 3.0 1.9 1 1 0 1 1 1 1 Sin-like protein conserved region IPK PF03770.16 KXT03387.1 - 3.2e-57 193.6 0.0 7.5e-57 192.4 0.0 1.7 1 0 0 1 1 1 1 Inositol polyphosphate kinase MAGUK_N_PEST PF10608.9 KXT03387.1 - 0.76 10.2 5.9 3.1 8.2 0.1 3.1 2 0 0 2 2 2 0 Polyubiquitination (PEST) N-terminal domain of MAGUK Glyco_hydro_31 PF01055.26 KXT03388.1 - 6.8e-86 289.2 8.5 9.8e-86 288.7 8.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF4968 PF16338.5 KXT03388.1 - 0.0014 18.9 0.0 0.0033 17.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) APH PF01636.23 KXT03389.1 - 4.3e-13 49.8 0.0 9.9e-13 48.6 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF4125 PF13526.6 KXT03389.1 - 0.016 14.9 0.2 0.51 9.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4125) DUF1679 PF07914.11 KXT03389.1 - 0.058 12.2 0.0 2.1 7.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) PPTA PF01239.22 KXT03389.1 - 0.079 12.7 1.6 2.1 8.2 0.5 2.7 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat DUF5086 PF16985.5 KXT03390.1 - 0.023 14.6 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5086) NAD_binding_10 PF13460.6 KXT03391.1 - 7.5e-12 45.5 0.0 1.1e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXT03391.1 - 4.2e-08 33.1 0.3 6.1e-08 32.5 0.3 1.2 1 0 0 1 1 1 1 NmrA-like family adh_short_C2 PF13561.6 KXT03391.1 - 0.00019 21.1 0.4 0.00048 19.7 0.2 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KXT03391.1 - 0.00066 19.2 0.1 0.016 14.7 0.1 2.4 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 KXT03391.1 - 0.0038 16.7 0.2 0.01 15.3 0.1 1.8 2 1 0 2 2 2 1 short chain dehydrogenase AA_permease_2 PF13520.6 KXT03392.1 - 2.7e-82 276.9 30.6 3.4e-82 276.6 30.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXT03392.1 - 3e-15 55.8 28.5 3.6e-15 55.5 28.5 1.1 1 0 0 1 1 1 1 Amino acid permease TarH PF02203.15 KXT03392.1 - 0.14 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Tar ligand binding domain homologue FA_desaturase PF00487.24 KXT03392.1 - 7.5 6.3 14.2 8 6.2 0.2 3.3 3 0 0 3 3 3 0 Fatty acid desaturase zf-C2H2_aberr PF17017.5 KXT03393.1 - 0.13 12.5 0.1 0.21 11.7 0.1 1.3 1 0 0 1 1 1 0 Aberrant zinc-finger Wyosine_form PF08608.12 KXT03394.1 - 1.4e-22 79.7 0.0 3.4e-22 78.6 0.0 1.7 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.21 KXT03394.1 - 1.4e-21 77.6 0.0 2.9e-21 76.6 0.0 1.6 1 1 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.25 KXT03394.1 - 6.6e-06 26.4 0.0 1.2e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin Pentapeptide PF00805.22 KXT03395.1 - 0.042 13.5 0.2 0.079 12.6 0.2 1.4 1 0 0 1 1 1 0 Pentapeptide repeats (8 copies) BAG PF02179.16 KXT03395.1 - 0.39 11.2 0.2 0.39 11.2 0.2 2.0 1 1 1 2 2 2 0 BAG domain APH PF01636.23 KXT03396.1 - 2.6e-16 60.3 0.0 3.7e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KXT03396.1 - 1.6e-06 27.8 0.6 0.0011 18.6 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Choline_kinase PF01633.20 KXT03396.1 - 0.00023 20.8 0.2 0.00057 19.5 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase PF00069.25 KXT03396.1 - 0.015 14.7 0.0 4 6.7 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain Fructosamin_kin PF03881.14 KXT03396.1 - 0.022 14.0 0.0 1.3 8.1 0.0 2.1 2 0 0 2 2 2 0 Fructosamine kinase EcKinase PF02958.20 KXT03396.1 - 0.028 13.8 0.1 0.057 12.7 0.1 1.5 1 0 0 1 1 1 0 Ecdysteroid kinase DUF1679 PF07914.11 KXT03396.1 - 0.097 11.5 0.1 0.16 10.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Gti1_Pac2 PF09729.9 KXT03410.1 - 3.9e-60 203.0 0.0 1.4e-59 201.3 0.0 1.8 2 0 0 2 2 2 1 Gti1/Pac2 family Gti1_Pac2 PF09729.9 KXT03411.1 - 3.9e-60 203.0 0.0 1.4e-59 201.3 0.0 1.8 2 0 0 2 2 2 1 Gti1/Pac2 family Sad1_UNC PF07738.13 KXT03413.1 - 3.7e-32 111.1 0.5 6.2e-32 110.4 0.5 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal MIF4G_like PF09088.11 KXT03414.1 - 2.1e-83 278.8 0.7 3.4e-83 278.1 0.7 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.11 KXT03414.1 - 3.7e-66 223.3 0.1 6.9e-66 222.5 0.1 1.4 1 0 0 1 1 1 1 MIF4G like Clr5 PF14420.6 KXT03415.1 - 8.4e-06 25.9 3.6 1.7e-05 25.0 2.5 2.1 2 0 0 2 2 2 1 Clr5 domain CDP-OH_P_transf PF01066.21 KXT03416.1 - 5.5e-14 52.7 0.4 5.5e-14 52.7 0.4 2.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Alpha_adaptinC2 PF02883.20 KXT03416.1 - 0.00014 22.1 0.2 0.00033 20.9 0.2 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain DUF3433 PF11915.8 KXT03417.1 - 1.9e-38 130.8 16.8 5.9e-21 74.7 2.8 4.0 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) DUF5527 PF17665.1 KXT03417.1 - 0.062 12.8 0.0 0.062 12.8 0.0 3.4 2 1 1 3 3 3 0 Family of unknown function (DUF5527) Mur_ligase_M PF08245.12 KXT03418.1 - 1.4e-08 34.9 0.0 2.8e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Mur ligase middle domain Glyco_hydro_61 PF03443.14 KXT03419.1 - 0.00081 19.4 0.1 0.0015 18.5 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 TAF6_C PF07571.13 KXT03420.1 - 9.9e-29 99.5 0.0 2.6e-28 98.2 0.0 1.8 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 KXT03420.1 - 5e-26 90.7 0.3 1.1e-25 89.6 0.3 1.6 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 KXT03420.1 - 9.4e-08 32.5 0.5 1e-05 25.9 0.4 2.4 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KXT03420.1 - 0.00015 22.0 0.7 0.00049 20.3 0.5 2.0 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KXT03420.1 - 0.0018 18.3 0.4 0.0044 17.1 0.4 1.6 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KXT03420.1 - 0.0095 15.9 0.1 0.024 14.7 0.1 1.6 1 0 0 1 1 1 1 Bromodomain associated CENP-S PF15630.6 KXT03420.1 - 0.057 13.8 0.1 0.18 12.2 0.1 1.8 1 0 0 1 1 1 0 CENP-S protein Ribosomal_S6e PF01092.19 KXT03421.1 - 0.041 13.8 0.0 0.37 10.8 0.0 2.4 3 0 0 3 3 3 0 Ribosomal protein S6e Myb_DNA-binding PF00249.31 KXT03421.1 - 0.14 12.3 0.0 1 9.6 0.0 2.3 2 1 0 2 2 2 0 Myb-like DNA-binding domain Ribosomal_S6e PF01092.19 KXT03422.1 - 0.041 13.8 0.0 0.37 10.8 0.0 2.4 3 0 0 3 3 3 0 Ribosomal protein S6e Myb_DNA-binding PF00249.31 KXT03422.1 - 0.14 12.3 0.0 1 9.6 0.0 2.3 2 1 0 2 2 2 0 Myb-like DNA-binding domain Radical_SAM_C PF16199.5 KXT03423.1 - 6.2e-32 109.5 0.2 1.9e-31 107.9 0.1 1.9 2 0 0 2 2 2 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 KXT03423.1 - 6.8e-16 59.1 0.0 1.8e-15 57.7 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 KXT03423.1 - 1.8e-08 34.6 0.2 4.2e-08 33.4 0.2 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXT03423.1 - 5e-05 23.3 0.0 0.00011 22.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXT03423.1 - 0.036 14.5 0.1 0.088 13.2 0.1 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain UQ_con PF00179.26 KXT03424.1 - 5.9e-50 168.6 0.0 6.6e-50 168.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme adh_short PF00106.25 KXT03425.1 - 8.8e-16 57.9 0.0 8.9e-15 54.7 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT03425.1 - 1.3e-08 34.7 0.0 1.9e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT03425.1 - 2.9e-08 33.9 0.1 4.1e-08 33.3 0.1 1.2 1 0 0 1 1 1 1 KR domain Aa_trans PF01490.18 KXT03426.1 - 5.8e-69 232.8 23.0 6.8e-69 232.5 23.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KXT03426.1 - 0.0002 20.5 5.2 0.0002 20.5 5.2 2.3 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family JSRP PF15312.6 KXT03426.1 - 0.06 13.3 0.5 0.83 9.6 0.1 2.6 2 0 0 2 2 2 0 Junctional sarcoplasmic reticulum protein STE PF02200.16 KXT03427.1 - 2.1e-56 189.1 0.1 3.4e-56 188.4 0.1 1.3 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 KXT03427.1 - 6.1e-10 39.0 11.1 5.2e-05 23.5 1.1 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXT03427.1 - 9e-08 32.2 2.8 9e-08 32.2 2.8 3.3 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXT03427.1 - 4.4e-07 30.2 8.7 0.0039 17.9 0.5 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KXT03427.1 - 0.00071 19.5 0.6 0.00071 19.5 0.6 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXT03427.1 - 0.0064 16.8 0.3 0.11 12.8 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXT03427.1 - 0.2 12.1 1.7 0.71 10.4 0.5 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Ribosomal_L19 PF01245.20 KXT03429.1 - 3.2e-14 52.8 0.1 5.4e-14 52.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L19 CFEM PF05730.11 KXT03431.1 - 1e-12 48.0 13.8 2e-12 47.0 13.8 1.5 1 0 0 1 1 1 1 CFEM domain DUF3169 PF11368.8 KXT03431.1 - 0.0043 16.6 0.1 0.0067 16.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3169) Pectinesterase PF01095.19 KXT03431.1 - 0.05 12.3 0.1 0.084 11.6 0.1 1.3 1 0 0 1 1 1 0 Pectinesterase EI24 PF07264.11 KXT03431.1 - 1.5 9.0 10.7 0.56 10.4 6.6 2.2 2 1 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) DUF4462 PF14692.6 KXT03431.1 - 2.7 7.5 6.2 13 5.3 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4462) Gcd10p PF04189.13 KXT03433.1 - 1.1e-109 366.2 0.0 1.4e-109 365.9 0.0 1.1 1 0 0 1 1 1 1 Gcd10p family GMC_oxred_N PF00732.19 KXT03434.1 - 5.6e-52 177.0 0.0 9.4e-52 176.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXT03434.1 - 6.7e-38 130.5 0.5 1.9e-37 129.0 0.1 1.9 2 0 0 2 2 2 1 GMC oxidoreductase Pyr_redox_3 PF13738.6 KXT03434.1 - 7.7e-06 25.4 0.4 0.0081 15.4 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXT03434.1 - 1.1e-05 25.1 0.0 0.00041 20.0 0.0 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXT03434.1 - 3.7e-05 23.0 0.1 0.0023 17.1 0.3 2.2 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 KXT03434.1 - 0.0007 18.8 0.7 0.0011 18.2 0.2 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KXT03434.1 - 0.0009 18.6 0.1 0.0018 17.5 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXT03434.1 - 0.0031 17.7 3.3 0.0037 17.4 1.2 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KXT03434.1 - 0.038 13.2 0.2 0.093 12.0 0.3 1.6 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 KXT03434.1 - 0.092 11.4 0.2 0.14 10.8 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein TrkA_N PF02254.18 KXT03434.1 - 0.11 12.7 0.1 0.24 11.6 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.17 KXT03434.1 - 0.14 11.4 0.1 0.25 10.5 0.1 1.3 1 0 0 1 1 1 0 Thi4 family MADF_DNA_bdg PF10545.9 KXT03439.1 - 0.0084 16.4 0.0 0.013 15.8 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Cupin_2 PF07883.11 KXT03442.1 - 4.6e-07 29.5 1.5 2.1e-05 24.2 1.5 2.4 1 1 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KXT03442.1 - 0.00067 19.3 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 KXT03442.1 - 0.0095 15.6 0.1 0.61 9.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF861) Cupin_6 PF12852.7 KXT03442.1 - 0.094 12.4 0.2 0.54 10.0 0.2 2.3 1 1 0 1 1 1 0 Cupin NPCC PF08058.11 KXT03445.1 - 3.4e-22 78.9 0.0 6.6e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 Nuclear pore complex component NAD_binding_2 PF03446.15 KXT03446.1 - 2.3e-34 118.9 0.0 3.4e-34 118.3 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KXT03446.1 - 4.5e-17 62.4 0.0 6.5e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KXT03446.1 - 5.9e-06 26.8 0.0 1.3e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.15 KXT03446.1 - 0.0087 15.0 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family HisKA PF00512.25 KXT03447.1 - 6.2e-13 48.6 0.0 1.8e-12 47.1 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Mito_fiss_reg PF05308.11 KXT03447.1 - 8.2 6.4 7.8 5.3 7.0 2.5 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator Methyltransf_23 PF13489.6 KXT03448.1 - 1e-23 84.0 0.0 1.7e-23 83.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXT03448.1 - 7.2e-09 36.2 0.0 2e-08 34.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXT03448.1 - 3.1e-06 27.7 0.0 1e-05 26.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXT03448.1 - 1.8e-05 24.5 0.0 0.074 12.9 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain PrmA PF06325.13 KXT03448.1 - 0.00049 19.6 0.0 0.00072 19.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 KXT03448.1 - 0.0012 19.5 0.0 0.014 16.2 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 KXT03448.1 - 0.01 15.2 0.0 0.04 13.2 0.0 1.9 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.9 KXT03448.1 - 0.012 15.4 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase MTS PF05175.14 KXT03448.1 - 0.035 13.6 0.0 0.069 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.19 KXT03448.1 - 0.042 13.6 0.0 1.1 9.0 0.0 2.2 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.16 KXT03448.1 - 0.056 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_23 PF13489.6 KXT03451.1 - 1.5e-23 83.4 0.0 2.3e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXT03451.1 - 5.9e-09 36.5 0.0 1.6e-08 35.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXT03451.1 - 2.4e-06 28.1 0.0 8.6e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXT03451.1 - 2.1e-05 24.3 0.0 0.1 12.4 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KXT03451.1 - 0.0011 19.7 0.0 0.011 16.4 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 KXT03451.1 - 0.0022 17.5 0.0 0.0031 17.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 KXT03451.1 - 0.021 14.6 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase MTS PF05175.14 KXT03451.1 - 0.029 13.9 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain CMAS PF02353.20 KXT03451.1 - 0.13 11.5 0.0 0.45 9.8 0.0 1.8 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Ribonuclease_T2 PF00445.18 KXT03453.1 - 7.1e-37 127.4 0.1 1.3e-36 126.6 0.1 1.3 1 0 0 1 1 1 1 Ribonuclease T2 family SET PF00856.28 KXT03454.1 - 1.5e-18 67.7 0.0 2.9e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 KXT03454.1 - 0.014 16.0 0.3 0.079 13.7 0.1 2.4 2 0 0 2 2 2 0 Rubisco LSMT substrate-binding FAM178 PF14816.6 KXT03454.1 - 0.08 11.9 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function, FAM178 T3SchapCesA PF11439.8 KXT03454.1 - 0.38 10.9 3.0 2.3 8.4 0.2 2.6 2 0 0 2 2 2 0 Type III secretion system filament chaperone CesA BBP1_C PF15272.6 KXT03455.1 - 0.5 10.2 2.0 1.7 8.4 0.2 2.4 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal Pkinase PF00069.25 KXT03457.1 - 8.6e-67 225.3 0.9 5.8e-66 222.5 0.9 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT03457.1 - 9.9e-53 179.1 0.1 1.8e-52 178.2 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KXT03457.1 - 2.7e-20 72.4 0.0 8e-20 71.0 0.0 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.29 KXT03457.1 - 1.2e-08 35.4 0.5 3.5e-08 33.9 0.5 1.9 1 0 0 1 1 1 1 PH domain Pkinase_fungal PF17667.1 KXT03457.1 - 2.4e-05 23.3 0.0 2.4e-05 23.3 0.0 3.2 4 0 0 4 4 4 1 Fungal protein kinase Kinase-like PF14531.6 KXT03457.1 - 0.00011 21.6 0.0 0.0002 20.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like KIND PF16474.5 KXT03457.1 - 0.032 14.1 0.0 0.032 14.1 0.0 2.2 2 0 0 2 2 2 0 Kinase non-catalytic C-lobe domain Haspin_kinase PF12330.8 KXT03457.1 - 0.058 12.3 0.2 0.11 11.4 0.2 1.4 1 0 0 1 1 1 0 Haspin like kinase domain PH_11 PF15413.6 KXT03457.1 - 0.18 12.2 4.5 0.58 10.6 0.9 3.2 2 1 0 2 2 2 0 Pleckstrin homology domain WRW PF10206.9 KXT03458.1 - 0.00076 19.8 0.1 0.002 18.5 0.1 1.7 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f WW PF00397.26 KXT03458.1 - 0.0015 18.6 4.2 0.0047 17.0 4.2 1.9 1 0 0 1 1 1 1 WW domain Aldo_ket_red PF00248.21 KXT03460.1 - 8.1e-46 156.5 0.0 1.1e-45 156.1 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family HTH_10 PF04967.12 KXT03460.1 - 0.2 11.5 1.2 15 5.5 0.0 3.6 4 0 0 4 4 4 0 HTH DNA binding domain Rieske PF00355.26 KXT03461.1 - 2.3e-10 40.3 0.0 4.2e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 KXT03461.1 - 5.4e-10 39.1 0.0 7.9e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain cobW PF02492.19 KXT03462.1 - 3e-49 167.0 3.9 3.3e-37 127.8 0.3 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KXT03462.1 - 7.4e-18 64.3 0.1 2e-13 50.1 0.0 2.5 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain MeaB PF03308.16 KXT03462.1 - 4.2e-06 25.9 0.1 0.0013 17.8 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB TsaE PF02367.17 KXT03462.1 - 0.0067 16.4 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE MobB PF03205.14 KXT03462.1 - 0.007 16.3 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B RsgA_GTPase PF03193.16 KXT03462.1 - 0.0075 16.2 0.4 1.7 8.5 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase Viral_helicase1 PF01443.18 KXT03462.1 - 0.0093 15.7 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase GTP_EFTU PF00009.27 KXT03462.1 - 0.0095 15.5 0.6 0.33 10.5 0.1 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KXT03462.1 - 0.016 15.6 0.1 0.046 14.1 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KXT03462.1 - 0.044 13.5 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 KXT03462.1 - 0.053 13.7 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KXT03462.1 - 0.069 13.7 0.1 0.5 10.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KXT03462.1 - 0.088 12.6 0.1 13 5.4 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein UPF0004 PF00919.20 KXT03462.1 - 0.09 12.8 0.6 0.27 11.3 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein family UPF0004 NACHT PF05729.12 KXT03462.1 - 0.16 11.9 0.0 0.44 10.4 0.0 1.8 1 0 0 1 1 1 0 NACHT domain PTPRCAP PF15713.5 KXT03462.1 - 2.5 8.4 8.5 0.45 10.8 2.0 2.4 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated EPL1 PF10513.9 KXT03463.1 - 7.3e-24 84.9 0.2 7.3e-24 84.9 0.2 2.7 3 1 0 3 3 3 1 Enhancer of polycomb-like Aminotran_1_2 PF00155.21 KXT03464.1 - 8.9e-82 275.2 0.0 1.2e-81 274.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KXT03464.1 - 1.4e-06 27.5 0.0 2.9e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KXT03464.1 - 1.1e-05 24.2 0.1 2.2e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KXT03464.1 - 5.7e-05 22.6 0.2 9.5e-05 21.9 0.2 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DUF3405 PF11885.8 KXT03464.1 - 0.012 14.3 0.5 0.02 13.5 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) Beta_elim_lyase PF01212.21 KXT03464.1 - 0.016 14.5 2.8 0.04 13.2 2.9 1.4 1 1 0 1 1 1 0 Beta-eliminating lyase Methyltransf_31 PF13847.6 KXT03464.1 - 0.074 12.8 0.0 2.9 7.7 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain AstE_AspA PF04952.14 KXT03465.1 - 8.1e-32 110.4 0.0 1e-31 110.1 0.0 1.1 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Biotin_lipoyl PF00364.22 KXT03465.1 - 0.2 11.5 0.5 1.5 8.7 0.2 2.4 2 0 0 2 2 2 0 Biotin-requiring enzyme SGL PF08450.12 KXT03466.1 - 4e-07 29.9 0.0 0.075 12.6 0.0 4.1 3 1 1 4 4 4 3 SMP-30/Gluconolactonase/LRE-like region Reg_prop PF07494.11 KXT03466.1 - 0.029 14.5 0.3 14 6.3 0.0 3.8 4 0 0 4 4 4 0 Two component regulator propeller OLF PF02191.16 KXT03466.1 - 0.051 13.1 0.2 21 4.5 0.0 3.7 3 1 0 4 4 4 0 Olfactomedin-like domain Antirestrict PF03230.13 KXT03466.1 - 0.099 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Antirestriction protein NmrA PF05368.13 KXT03467.1 - 2.6e-08 33.7 0.0 2.9e-08 33.6 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXT03467.1 - 0.00053 19.9 0.0 0.00061 19.7 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding TPR_2 PF07719.17 KXT03469.1 - 3.3e-05 23.6 0.6 2.8 8.3 0.7 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat UBA PF00627.31 KXT03469.1 - 6.4e-05 22.8 0.0 0.00015 21.6 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain DnaJ PF00226.31 KXT03469.1 - 0.031 14.4 0.0 0.085 13.0 0.0 1.7 1 0 0 1 1 1 0 DnaJ domain Sec1 PF00995.23 KXT03470.1 - 1.3e-133 447.3 0.0 1.5e-133 447.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Abhydrolase_4 PF08386.10 KXT03470.1 - 0.13 12.4 0.1 0.68 10.1 0.0 2.1 2 0 0 2 2 2 0 TAP-like protein SPC12 PF06645.13 KXT03473.1 - 1.1e-27 95.9 0.7 1.3e-27 95.7 0.7 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF2627 PF11118.8 KXT03473.1 - 0.03 14.9 0.1 0.052 14.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) BCS1_N PF08740.11 KXT03474.1 - 2.7e-41 141.6 0.1 5.7e-41 140.5 0.1 1.5 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KXT03474.1 - 1.9e-16 60.7 0.0 1e-07 32.4 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KXT03474.1 - 0.0065 16.2 0.0 0.036 13.8 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KXT03474.1 - 0.011 16.1 0.0 0.024 15.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain ATPase PF06745.13 KXT03474.1 - 0.033 13.5 0.0 0.14 11.5 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_5 PF07728.14 KXT03474.1 - 0.12 12.3 0.0 0.31 11.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KXT03474.1 - 0.14 12.3 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KXT03474.1 - 0.17 11.7 1.4 0.46 10.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain Striatin PF08232.12 KXT03475.1 - 5.1e-43 147.3 9.1 5.1e-43 147.3 9.1 2.0 2 0 0 2 2 2 1 Striatin family WD40 PF00400.32 KXT03475.1 - 2.4e-21 75.6 20.7 0.00018 22.2 0.1 8.1 8 1 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXT03475.1 - 0.00018 21.8 0.0 0.77 10.1 0.0 3.9 3 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain KLRAQ PF10205.9 KXT03475.1 - 0.11 12.7 2.0 0.23 11.7 2.0 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein EVC2_like PF12297.8 KXT03475.1 - 0.21 10.2 3.6 0.34 9.5 3.6 1.2 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein Metallophos PF00149.28 KXT03476.1 - 2.8e-35 122.7 0.1 4.9e-35 121.9 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos PF00149.28 KXT03477.1 - 2.5e-35 122.9 0.1 4.1e-35 122.1 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1647 PF07801.11 KXT03477.1 - 0.13 12.0 0.9 2.2 8.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) DUF1996 PF09362.10 KXT03478.1 - 2e-68 230.9 1.1 3.2e-68 230.2 1.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.19 KXT03478.1 - 8.4e-42 141.3 50.8 5.8e-15 55.3 7.3 4.3 4 0 0 4 4 4 3 WSC domain Atg29_N PF18388.1 KXT03478.1 - 0.19 11.6 0.2 0.42 10.5 0.0 1.7 2 0 0 2 2 2 0 Atg29 N-terminal domain adh_short PF00106.25 KXT03480.1 - 1e-19 70.8 0.0 2e-19 69.9 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT03480.1 - 2e-11 43.9 0.0 2.7e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KXT03480.1 - 1.4e-09 37.8 0.0 1.5e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) PALP PF00291.25 KXT03482.1 - 2e-66 224.4 0.2 2.3e-66 224.2 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Cellulase PF00150.18 KXT03483.1 - 7.3e-13 48.6 4.3 1.7e-12 47.4 4.3 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) zf-rbx1 PF12678.7 KXT03484.1 - 4.1e-25 87.8 12.9 6.1e-25 87.3 12.9 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KXT03484.1 - 3.1e-17 62.4 10.1 4.2e-17 62.0 10.1 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 KXT03484.1 - 2.9e-06 27.5 14.8 0.00011 22.5 14.8 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KXT03484.1 - 0.0015 18.4 11.6 0.021 14.7 11.6 2.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXT03484.1 - 0.0038 17.1 14.7 0.0038 17.1 9.1 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXT03484.1 - 0.21 11.3 15.3 18 5.2 15.3 2.4 1 1 0 1 1 1 0 RING-like zinc finger zf-C3HC4_3 PF13920.6 KXT03484.1 - 0.32 10.9 10.8 1 9.3 4.5 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXT03484.1 - 0.4 10.7 7.6 1.4 9.0 7.6 2.0 1 1 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.8 KXT03484.1 - 0.57 10.4 9.4 3 8.1 9.7 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 KXT03484.1 - 0.69 9.6 14.7 0.17 11.5 5.0 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type MaoC_dehydratas PF01575.19 KXT03485.1 - 0.011 15.3 0.0 0.031 13.8 0.0 1.7 2 0 0 2 2 2 0 MaoC like domain 2-Hacid_dh_C PF02826.19 KXT03487.1 - 3.6e-49 166.5 0.0 6.9e-49 165.6 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXT03487.1 - 4.5e-36 123.5 0.1 5.9e-36 123.1 0.1 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 KXT03487.1 - 6e-05 22.7 0.0 0.00012 21.7 0.0 1.6 1 0 0 1 1 1 1 ACT domain NAD_binding_2 PF03446.15 KXT03487.1 - 0.00014 22.1 0.8 0.00079 19.6 0.2 2.4 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 KXT03487.1 - 0.021 14.9 0.2 0.052 13.6 0.0 1.7 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.18 KXT03487.1 - 0.072 13.0 0.9 5.9 6.7 0.4 2.8 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.6 KXT03487.1 - 0.097 13.2 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain DUF1780 PF08682.10 KXT03487.1 - 0.21 11.2 0.0 0.4 10.3 0.0 1.4 1 0 0 1 1 1 0 Putative endonuclease, protein of unknown function (DUF1780) CorA PF01544.18 KXT03488.1 - 9.3e-44 149.9 0.0 1.2e-43 149.5 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein PHD PF00628.29 KXT03489.1 - 6.3e-08 32.4 6.5 6.3e-08 32.4 6.5 2.9 3 0 0 3 3 3 1 PHD-finger PHD_2 PF13831.6 KXT03489.1 - 0.18 11.4 7.8 0.18 11.4 1.9 2.6 2 0 0 2 2 2 0 PHD-finger zf-C2H2_4 PF13894.6 KXT03489.1 - 1 10.4 13.7 0.3 12.1 0.3 5.2 3 1 0 3 3 3 0 C2H2-type zinc finger TolA_bind_tri PF16331.5 KXT03489.1 - 3.7 7.7 9.1 0.26 11.4 3.3 2.1 2 0 0 2 2 2 0 TolA binding protein trimerisation PDT PF00800.18 KXT03490.1 - 6.9e-56 188.9 0.1 1.7e-55 187.7 0.1 1.6 1 1 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 KXT03490.1 - 0.0073 16.1 0.0 2.5 7.9 0.0 2.8 2 1 1 3 3 3 2 ACT domain Phos_pyr_kin PF08543.12 KXT03490.1 - 0.08 12.3 0.3 0.13 11.7 0.3 1.2 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase Pkinase PF00069.25 KXT03495.1 - 5.6e-12 45.6 0.0 7e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT03495.1 - 2.7e-11 43.3 0.0 3.3e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXT03495.1 - 0.18 11.7 2.5 0.59 10.0 1.3 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family UBA_4 PF14555.6 KXT03496.1 - 9.9e-08 31.7 0.1 2.1e-07 30.6 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain ASD2 PF08687.11 KXT03496.1 - 0.00017 21.3 3.4 0.06 12.9 3.5 2.6 2 0 0 2 2 2 2 Apx/Shroom domain ASD2 UIM PF02809.20 KXT03496.1 - 0.0031 17.3 1.1 0.0031 17.3 1.1 2.3 2 0 0 2 2 2 1 Ubiquitin interaction motif PNK3P PF08645.11 KXT03496.1 - 0.015 15.0 0.0 3 7.5 0.0 2.4 2 0 0 2 2 2 0 Polynucleotide kinase 3 phosphatase DUF5082 PF16888.5 KXT03496.1 - 0.053 13.8 4.2 0.13 12.6 2.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) DUF4047 PF13256.6 KXT03496.1 - 0.13 12.4 0.5 13 6.0 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) YkyA PF10368.9 KXT03496.1 - 0.66 9.6 6.2 0.066 12.9 0.4 2.2 3 0 0 3 3 3 0 Putative cell-wall binding lipoprotein G10 PF01125.17 KXT03497.1 - 8.4e-62 207.3 10.7 9.5e-62 207.1 10.7 1.0 1 0 0 1 1 1 1 G10 protein Forkhead PF00250.18 KXT03498.1 - 9.8e-35 118.7 0.1 3.3e-34 117.0 0.0 1.9 2 0 0 2 2 2 1 Forkhead domain GIDA PF01134.22 KXT03499.1 - 6.8e-156 519.3 0.0 8.3e-156 519.0 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 KXT03499.1 - 7.8e-70 235.3 0.0 1.1e-69 234.8 0.0 1.2 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 KXT03499.1 - 1.8e-06 27.6 0.4 3e-06 26.8 0.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXT03499.1 - 1.2e-05 24.7 0.6 2.4e-05 23.7 0.6 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXT03499.1 - 0.00018 20.7 2.4 0.00018 20.7 2.4 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KXT03499.1 - 0.00038 20.9 0.2 0.0011 19.5 0.2 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KXT03499.1 - 0.0019 17.5 0.2 0.0037 16.6 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KXT03499.1 - 0.016 14.0 0.9 0.092 11.4 0.3 2.1 2 0 0 2 2 2 0 HI0933-like protein DAO PF01266.24 KXT03499.1 - 0.022 14.4 1.6 2.7 7.5 0.7 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXT03499.1 - 0.045 13.0 0.0 0.12 11.6 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXT03499.1 - 0.065 12.3 0.1 0.1 11.6 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein UQ_con PF00179.26 KXT03500.1 - 2.2e-38 131.1 0.1 3.2e-38 130.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KXT03500.1 - 0.07 13.4 1.9 0.079 13.2 1.0 1.7 1 1 1 2 2 2 0 RWD domain YL1 PF05764.13 KXT03500.1 - 4.7 7.3 19.2 6 6.9 19.2 1.2 1 0 0 1 1 1 0 YL1 nuclear protein FrhB_FdhB_N PF04422.13 KXT03501.1 - 0.065 13.4 0.0 0.092 12.9 0.0 1.3 1 0 0 1 1 1 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term F-box PF00646.33 KXT03502.1 - 0.001 18.9 0.2 0.051 13.5 0.0 2.6 3 0 0 3 3 3 1 F-box domain ADH_zinc_N_2 PF13602.6 KXT03504.1 - 1.4e-13 52.1 0.0 6.9e-13 49.8 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KXT03504.1 - 1.9e-06 27.9 0.0 4.1e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Oxidored_nitro PF00148.19 KXT03504.1 - 0.0051 15.6 0.0 0.0072 15.1 0.0 1.1 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase ADH_N PF08240.12 KXT03504.1 - 0.0078 16.1 0.2 0.017 15.0 0.1 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Striatin PF08232.12 KXT03505.1 - 2.4 8.7 10.0 1.8 9.1 1.0 3.3 4 0 0 4 4 4 0 Striatin family Pkinase PF00069.25 KXT03506.1 - 1.2e-15 57.6 0.0 3.8e-15 56.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain DUF2909 PF11137.8 KXT03506.1 - 0.086 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2909) ASFV_J13L PF05568.11 KXT03507.1 - 0.78 9.5 7.4 1.1 9.0 7.4 1.2 1 0 0 1 1 1 0 African swine fever virus J13L protein DUF3245 PF11595.8 KXT03508.1 - 0.00042 20.8 2.6 0.00046 20.7 2.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3245) Myb_DNA-binding PF00249.31 KXT03508.1 - 0.065 13.4 0.0 0.15 12.3 0.0 1.7 1 1 0 1 1 1 0 Myb-like DNA-binding domain DUF4677 PF15726.5 KXT03508.1 - 0.069 13.3 0.8 0.08 13.1 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4677) NOA36 PF06524.12 KXT03508.1 - 0.11 11.8 2.3 0.13 11.6 2.3 1.1 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 KXT03508.1 - 1.5 8.5 4.0 1.9 8.1 4.0 1.2 1 0 0 1 1 1 0 FAM176 family PhyH PF05721.13 KXT03509.1 - 3.5e-24 86.2 0.0 4.9e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) POT1 PF02765.17 KXT03510.1 - 3.3e-09 36.7 0.0 9e-09 35.3 0.0 1.7 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 TrkH PF02386.16 KXT03511.1 - 4.4e-149 497.2 6.8 4.4e-149 497.2 6.8 2.1 2 0 0 2 2 2 2 Cation transport protein Cpn60_TCP1 PF00118.24 KXT03512.1 - 4.3e-84 282.9 12.6 7.2e-84 282.2 12.6 1.3 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pkinase PF00069.25 KXT03513.1 - 1.7e-18 66.9 0.0 6.6e-18 65.0 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT03513.1 - 4.2e-05 23.0 0.0 0.00056 19.3 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase DnaJ PF00226.31 KXT03514.1 - 4.4e-09 36.3 0.1 9e-09 35.3 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain DUF4168 PF13767.6 KXT03514.1 - 0.0027 18.8 0.0 0.0084 17.3 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4168) Myb_DNA-binding PF00249.31 KXT03515.1 - 0.0018 18.4 0.0 0.0041 17.3 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain RNA_polI_A34 PF08208.11 KXT03515.1 - 0.51 10.4 12.1 0.6 10.2 12.1 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Cnd3 PF12719.7 KXT03516.1 - 7.2e-84 281.5 6.5 2.1e-83 279.9 2.2 2.7 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 KXT03516.1 - 1.8e-07 30.8 7.0 0.041 14.1 0.0 7.3 8 0 0 8 8 8 2 HEAT repeat HEAT_2 PF13646.6 KXT03516.1 - 3.5e-07 30.5 13.9 0.00014 22.2 0.9 6.3 5 2 1 6 6 6 3 HEAT repeats Cnd1 PF12717.7 KXT03516.1 - 0.0063 16.6 7.0 0.77 9.8 0.1 4.8 5 1 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 KXT03516.1 - 0.008 16.4 0.4 0.25 11.5 0.1 3.4 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 GhoS PF11080.8 KXT03516.1 - 0.28 11.2 1.8 0.48 10.4 0.1 2.3 2 0 0 2 2 2 0 Endoribonuclease GhoS HEAT_EZ PF13513.6 KXT03516.1 - 1.3 9.6 12.4 1.1 9.9 0.2 6.0 7 1 0 7 7 7 0 HEAT-like repeat Mo25 PF08569.11 KXT03516.1 - 8.2 5.7 8.0 27 4.0 0.0 3.8 3 2 0 4 4 4 0 Mo25-like Glyco_hydro_114 PF03537.13 KXT03519.1 - 2.8e-80 269.0 0.3 3.6e-80 268.6 0.3 1.1 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 SPC22 PF04573.12 KXT03521.1 - 5e-41 140.0 0.2 1.5e-27 96.2 0.0 2.1 2 0 0 2 2 2 2 Signal peptidase subunit DUF3472 PF11958.8 KXT03522.1 - 0.1 13.1 0.0 2 8.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3472) Glyco_hydro_3_C PF01915.22 KXT03524.1 - 4.7e-44 150.8 0.0 1e-43 149.7 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXT03524.1 - 4.4e-40 138.0 0.0 8e-40 137.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXT03524.1 - 2.5e-19 69.2 0.1 4.8e-19 68.2 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3_C PF01915.22 KXT03525.1 - 4.7e-44 150.8 0.0 1e-43 149.7 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXT03525.1 - 4.4e-40 138.0 0.0 8e-40 137.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXT03525.1 - 2.5e-19 69.2 0.1 4.8e-19 68.2 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain ORC2 PF04084.14 KXT03526.1 - 2.7e-120 401.2 0.0 3.4e-120 400.9 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 Drc1-Sld2 PF11719.8 KXT03526.1 - 0.0058 16.2 14.0 0.011 15.3 12.4 1.9 2 0 0 2 2 2 1 DNA replication and checkpoint protein Rhabdo_ncap PF00945.18 KXT03526.1 - 0.52 9.1 4.4 0.78 8.6 4.4 1.2 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein ORC6 PF05460.13 KXT03526.1 - 4 6.6 21.5 0.047 13.0 13.3 1.9 2 1 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) Glyco_hydro_18 PF00704.28 KXT03530.1 - 7.9e-84 282.0 3.8 9.7e-84 281.7 3.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.28 KXT03531.1 - 7.9e-84 282.0 3.8 9.7e-84 281.7 3.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Methyltransf_2 PF00891.18 KXT03533.1 - 2.6e-23 82.4 0.0 4.2e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 KXT03533.1 - 0.00028 21.5 0.0 0.00088 19.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXT03533.1 - 0.058 14.1 0.0 0.11 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain AT_hook PF02178.19 KXT03534.1 - 0.47 10.5 9.7 0.21 11.6 6.3 2.3 2 0 0 2 2 2 0 AT hook motif Pox_Ag35 PF03286.14 KXT03534.1 - 1.6 8.5 14.6 2.1 8.1 14.6 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein AT_hook PF02178.19 KXT03535.1 - 0.47 10.5 9.7 0.21 11.6 6.3 2.3 2 0 0 2 2 2 0 AT hook motif Pox_Ag35 PF03286.14 KXT03535.1 - 1.6 8.5 14.6 2.1 8.1 14.6 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CMAS PF02353.20 KXT03536.1 - 1.5e-34 119.6 0.3 2.1e-34 119.1 0.3 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 KXT03536.1 - 1.6e-14 54.0 0.0 2.2e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXT03536.1 - 8.7e-12 45.5 0.0 1.6e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXT03536.1 - 1e-11 45.0 0.0 1.6e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXT03536.1 - 1.1e-11 45.2 0.0 2.4e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXT03536.1 - 2.1e-09 38.0 0.0 3.9e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXT03536.1 - 8.3e-06 25.4 0.0 1.9e-05 24.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltr_RsmB-F PF01189.17 KXT03536.1 - 1e-05 25.3 0.0 2.5e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F TehB PF03848.14 KXT03536.1 - 0.0003 20.2 0.1 0.0014 18.1 0.0 1.9 2 0 0 2 2 2 1 Tellurite resistance protein TehB DUF938 PF06080.12 KXT03536.1 - 0.0027 17.5 0.0 0.0041 16.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) GCD14 PF08704.10 KXT03536.1 - 0.0043 16.8 0.0 0.01 15.5 0.0 1.5 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_4 PF02390.17 KXT03536.1 - 0.0049 16.3 0.0 0.0097 15.4 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.19 KXT03536.1 - 0.0056 16.5 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 KXT03536.1 - 0.018 15.1 0.0 0.23 11.5 0.0 2.1 1 1 0 1 1 1 0 FtsJ-like methyltransferase MyTH4 PF00784.17 KXT03536.1 - 0.035 14.6 0.1 0.096 13.2 0.1 1.8 1 0 0 1 1 1 0 MyTH4 domain FTO_CTD PF12934.7 KXT03536.1 - 0.091 12.5 2.8 0.11 12.2 1.6 1.7 1 1 0 1 1 1 0 FTO C-terminal domain RrnaAD PF00398.20 KXT03536.1 - 0.12 11.4 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase adh_short PF00106.25 KXT03537.1 - 7.4e-22 77.8 0.0 9.4e-22 77.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT03537.1 - 3.7e-18 65.9 0.0 4.5e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KXT03537.1 - 3.8e-07 30.2 0.2 1.8e-06 28.0 0.2 1.9 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KXT03537.1 - 1.9e-05 24.7 0.1 2.9e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KXT03537.1 - 0.01 15.2 0.3 0.11 11.9 0.1 2.0 1 1 1 2 2 2 0 Fungal family of unknown function (DUF1776) 3Beta_HSD PF01073.19 KXT03537.1 - 0.014 14.5 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1993 PF09351.10 KXT03538.1 - 1.2e-50 171.8 0.1 1.3e-50 171.7 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) DUF348 PF03990.14 KXT03538.1 - 0.032 14.0 0.1 3.1 7.6 0.1 2.4 2 0 0 2 2 2 0 G5-linked-Ubiquitin-like domain TPR_20 PF14561.6 KXT03538.1 - 0.14 12.5 0.5 2.5 8.5 0.1 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF1993 PF09351.10 KXT03539.1 - 1.2e-50 171.8 0.1 1.3e-50 171.7 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) DUF348 PF03990.14 KXT03539.1 - 0.032 14.0 0.1 3.1 7.6 0.1 2.4 2 0 0 2 2 2 0 G5-linked-Ubiquitin-like domain TPR_20 PF14561.6 KXT03539.1 - 0.14 12.5 0.5 2.5 8.5 0.1 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF1993 PF09351.10 KXT03540.1 - 1.2e-50 171.8 0.1 1.3e-50 171.7 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) DUF348 PF03990.14 KXT03540.1 - 0.032 14.0 0.1 3.1 7.6 0.1 2.4 2 0 0 2 2 2 0 G5-linked-Ubiquitin-like domain TPR_20 PF14561.6 KXT03540.1 - 0.14 12.5 0.5 2.5 8.5 0.1 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat AMP-binding PF00501.28 KXT03541.1 - 2.8e-15 55.9 0.0 1.5e-14 53.5 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme Glyco_trans_2_3 PF13632.6 KXT03543.1 - 6e-15 55.7 0.8 6e-15 55.7 0.8 2.3 1 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 KXT03543.1 - 1e-14 54.4 0.0 1.6e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 KXT03543.1 - 5.7e-08 32.9 0.0 1.1e-07 32.0 0.0 1.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KXT03543.1 - 0.00075 19.3 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 CoA_binding PF02629.19 KXT03547.1 - 5.8e-27 94.2 2.5 1.2e-26 93.2 0.8 2.2 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 KXT03547.1 - 2.2e-24 86.0 0.6 3.5e-24 85.4 0.6 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KXT03547.1 - 1.6e-06 28.0 0.1 2.6e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KXT03547.1 - 0.0014 19.1 0.0 0.0039 17.7 0.0 1.8 2 0 0 2 2 2 1 CoA binding domain IlvN PF07991.12 KXT03547.1 - 0.033 13.8 0.0 0.057 13.0 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain IBR PF01485.21 KXT03548.1 - 4.9e-05 23.5 5.4 4.9e-05 23.5 5.4 3.4 3 2 0 3 3 3 2 IBR domain, a half RING-finger domain GCD14 PF08704.10 KXT03556.1 - 1.2e-08 34.9 0.0 2.2e-07 30.8 0.0 2.4 1 1 1 2 2 2 1 tRNA methyltransferase complex GCD14 subunit GCD14_N PF14801.6 KXT03556.1 - 2.4e-06 27.3 0.0 4.8e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term Methyltransf_24 PF13578.6 KXT03556.1 - 2.3e-05 25.4 0.0 6.1e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXT03556.1 - 6.7e-05 22.7 0.0 0.0001 22.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXT03556.1 - 0.0014 19.3 0.1 0.0062 17.2 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXT03556.1 - 0.065 14.0 0.0 0.17 12.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Hexokinase_2 PF03727.16 KXT03557.1 - 4.3e-79 265.3 0.0 5.8e-79 264.9 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KXT03557.1 - 5.1e-75 251.7 0.0 9.2e-75 250.9 0.0 1.4 1 0 0 1 1 1 1 Hexokinase HMGL-like PF00682.19 KXT03557.1 - 0.061 12.9 0.8 6.8 6.2 0.2 2.3 2 0 0 2 2 2 0 HMGL-like MMR_HSR1_C PF08438.10 KXT03558.1 - 2.4e-35 121.5 0.0 4e-35 120.8 0.0 1.4 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 KXT03558.1 - 3.5e-16 59.3 0.0 9.6e-16 57.9 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXT03558.1 - 0.001 18.6 0.0 0.0083 15.7 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 KXT03558.1 - 0.011 15.3 0.1 0.69 9.4 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Ploopntkinase3 PF18751.1 KXT03558.1 - 0.055 13.4 0.0 0.18 11.7 0.0 1.8 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 RsgA_GTPase PF03193.16 KXT03558.1 - 0.088 12.7 0.1 3.3 7.6 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase Dynamin_N PF00350.23 KXT03558.1 - 0.091 12.8 0.4 0.45 10.5 0.1 2.2 3 0 0 3 3 3 0 Dynamin family MMR_HSR1_C PF08438.10 KXT03559.1 - 2.3e-35 121.5 0.0 3.9e-35 120.8 0.0 1.4 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 KXT03559.1 - 1.2e-14 54.3 0.0 3.9e-14 52.7 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXT03559.1 - 0.0016 18.0 0.1 0.014 15.0 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 KXT03559.1 - 0.0052 16.4 0.1 0.67 9.5 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KXT03559.1 - 0.071 13.2 0.1 0.43 10.6 0.0 2.2 3 0 0 3 3 3 0 Dynamin family Ploopntkinase3 PF18751.1 KXT03559.1 - 0.081 12.8 0.0 0.27 11.1 0.0 1.8 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 RsgA_GTPase PF03193.16 KXT03559.1 - 0.095 12.6 0.2 3.2 7.6 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase MMR_HSR1_C PF08438.10 KXT03560.1 - 1.1e-35 122.6 0.0 1.7e-35 122.0 0.0 1.3 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 KXT03560.1 - 1e-16 61.1 0.0 3.6e-16 59.3 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXT03560.1 - 0.00028 20.5 0.0 0.0042 16.6 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 KXT03560.1 - 0.0027 17.3 0.1 0.32 10.5 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Ploopntkinase3 PF18751.1 KXT03560.1 - 0.022 14.7 0.0 0.095 12.6 0.0 1.9 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 RsgA_GTPase PF03193.16 KXT03560.1 - 0.025 14.5 0.1 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase Dynamin_N PF00350.23 KXT03560.1 - 0.025 14.6 0.4 0.25 11.4 0.1 2.5 3 0 0 3 3 3 0 Dynamin family ABC_tran PF00005.27 KXT03560.1 - 0.13 12.8 0.0 0.7 10.4 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_33 PF13671.6 KXT03560.1 - 0.17 12.0 0.0 4.8 7.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KXT03560.1 - 0.18 12.0 0.1 0.35 11.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain PS_Dcarbxylase PF02666.15 KXT03561.1 - 2.4e-57 193.8 0.0 3.9e-57 193.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 KXT03561.1 - 1.8e-43 147.0 0.1 7.9e-21 74.3 0.0 2.5 2 0 0 2 2 2 2 C2 domain EF-hand_6 PF13405.6 KXT03561.1 - 0.0099 15.7 0.2 0.067 13.2 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 KXT03561.1 - 0.011 15.2 0.0 0.026 14.0 0.0 1.7 1 0 0 1 1 1 0 EF hand EF-hand_1 PF00036.32 KXT03561.1 - 0.016 14.7 0.0 0.051 13.1 0.0 1.9 1 0 0 1 1 1 0 EF hand CDC45 PF02724.14 KXT03561.1 - 0.35 9.1 6.4 0.63 8.3 6.4 1.3 1 0 0 1 1 1 0 CDC45-like protein IR1-M PF12185.8 KXT03561.1 - 5.6 7.0 6.0 3.8 7.5 0.2 2.6 2 0 0 2 2 2 0 Nup358/RanBP2 E3 ligase domain Shugoshin_N PF07558.11 KXT03564.1 - 0.00024 20.9 12.6 0.58 10.1 0.1 5.3 5 0 0 5 5 5 2 Shugoshin N-terminal coiled-coil region TPR_MLP1_2 PF07926.12 KXT03564.1 - 0.00068 19.7 3.2 0.00068 19.7 3.2 4.5 2 1 2 4 4 3 1 TPR/MLP1/MLP2-like protein HALZ PF02183.18 KXT03564.1 - 0.0038 17.4 18.5 0.12 12.6 1.1 5.1 5 1 1 6 6 5 2 Homeobox associated leucine zipper bZIP_1 PF00170.21 KXT03564.1 - 0.0072 16.4 16.6 0.66 10.1 0.2 5.3 3 2 2 5 5 5 3 bZIP transcription factor DUF2935 PF11155.8 KXT03564.1 - 0.097 13.0 5.9 0.18 12.1 1.5 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF2935) UPF0449 PF15136.6 KXT03564.1 - 0.14 12.6 0.0 0.14 12.6 0.0 4.0 4 1 0 4 4 4 0 Uncharacterised protein family UPF0449 UPF0184 PF03670.13 KXT03564.1 - 0.17 12.3 6.8 7.4 7.0 4.1 3.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) TMF_DNA_bd PF12329.8 KXT03564.1 - 0.22 11.5 11.2 3.8 7.6 0.3 3.7 2 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding CLZ PF16526.5 KXT03564.1 - 0.31 11.4 22.6 2 8.8 2.5 5.5 4 2 1 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Spc7 PF08317.11 KXT03564.1 - 0.39 9.6 30.5 1.4 7.7 1.7 4.0 1 1 3 4 4 4 0 Spc7 kinetochore protein Syntaxin_2 PF14523.6 KXT03564.1 - 0.46 10.9 19.8 4.5 7.7 5.2 4.1 3 1 1 4 4 4 0 Syntaxin-like protein IFT57 PF10498.9 KXT03564.1 - 0.48 9.3 27.1 0.1 11.5 8.0 3.5 1 1 2 3 3 3 0 Intra-flagellar transport protein 57 KASH_CCD PF14662.6 KXT03564.1 - 0.6 9.9 31.6 1.2 8.9 10.1 3.8 2 2 2 4 4 4 0 Coiled-coil region of CCDC155 or KASH VPS53_C PF16854.5 KXT03564.1 - 1 9.2 6.1 2.4 8.0 0.6 3.1 2 2 0 3 3 3 0 Vacuolar protein sorting-associated protein 53 C-terminus DUF5082 PF16888.5 KXT03564.1 - 1.4 9.2 13.4 2.6 8.3 0.1 4.4 3 2 0 3 3 3 0 Domain of unknown function (DUF5082) FlaC_arch PF05377.11 KXT03564.1 - 6.6 7.2 13.7 15 6.0 0.2 4.8 3 1 2 5 5 5 0 Flagella accessory protein C (FlaC) Spectrin_like PF18373.1 KXT03564.1 - 7.8 6.6 6.6 4.5 7.4 0.1 3.6 3 1 0 3 3 3 0 Spectrin like domain JIP_LZII PF16471.5 KXT03564.1 - 7.9 6.7 25.9 0.091 12.9 6.1 4.6 5 1 1 6 6 5 0 JNK-interacting protein leucine zipper II YabA PF06156.13 KXT03564.1 - 8.4 7.1 25.2 3.2 8.4 1.9 4.6 2 2 2 4 4 4 0 Initiation control protein YabA ABC_tran_CTD PF16326.5 KXT03564.1 - 9.7 6.5 25.5 1.6 9.0 0.7 5.5 3 1 3 6 6 6 0 ABC transporter C-terminal domain Hydrolase_6 PF13344.6 KXT03565.1 - 1e-24 86.5 0.0 2e-24 85.6 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXT03565.1 - 2e-13 50.2 0.0 8.1e-13 48.2 0.0 2.1 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 KXT03565.1 - 0.0033 17.8 0.0 6 7.1 0.0 3.2 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KXT03565.1 - 0.19 11.8 0.1 1.1 9.3 0.0 2.2 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase CPL PF08144.11 KXT03567.1 - 1.6e-33 116.1 0.4 9.8e-32 110.3 0.0 3.7 4 1 1 5 5 5 1 CPL (NUC119) domain GCN5L1 PF06320.13 KXT03567.1 - 0.079 13.1 4.0 0.91 9.7 1.1 2.7 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) Spt5_N PF11942.8 KXT03567.1 - 1.9 9.5 11.7 0.28 12.2 6.6 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal ASD2 PF08687.11 KXT03567.1 - 9.8 5.6 13.2 1.7 8.1 8.7 1.9 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 HMG_box_2 PF09011.10 KXT03568.1 - 2.2e-08 34.6 5.2 1.1e-05 25.9 0.1 3.6 3 0 0 3 3 3 2 HMG-box domain HMG_box PF00505.19 KXT03568.1 - 5.1e-05 23.6 0.1 5.1e-05 23.6 0.1 4.1 3 2 0 3 3 3 2 HMG (high mobility group) box Phage_cap_E PF03864.15 KXT03568.1 - 0.88 8.7 7.1 1.2 8.3 6.0 1.7 1 1 1 2 2 2 0 Phage major capsid protein E SOBP PF15279.6 KXT03568.1 - 9.8 6.7 12.2 14 6.2 12.2 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Ribosomal_S3_C PF00189.20 KXT03569.1 - 1.3e-24 86.5 0.2 5.9e-24 84.4 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 KXT03569.1 - 1.2e-09 37.8 0.0 2.2e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 KH domain Pkinase PF00069.25 KXT03570.1 - 2.1e-47 161.7 0.0 3.2e-47 161.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT03570.1 - 5.6e-15 55.3 0.0 9.5e-15 54.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXT03570.1 - 0.00036 20.5 0.0 0.0011 19.0 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family PTR2 PF00854.21 KXT03571.1 - 8.1e-46 156.6 0.6 1.4e-45 155.8 0.6 1.4 1 0 0 1 1 1 1 POT family Amastin PF07344.11 KXT03571.1 - 2.9 7.7 5.5 2 8.2 0.9 2.3 2 0 0 2 2 2 0 Amastin surface glycoprotein Glyco_hydro_17 PF00332.18 KXT03572.1 - 3.7e-32 112.2 0.7 6e-31 108.2 0.7 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 Bmp PF02608.14 KXT03572.1 - 0.038 13.0 0.0 0.17 10.8 0.0 2.1 1 1 1 2 2 2 0 ABC transporter substrate-binding protein PnrA-like Docking PF08990.11 KXT03573.1 - 0.0061 16.1 1.4 0.0061 16.1 1.4 3.4 3 0 0 3 3 3 2 Erythronolide synthase docking GST_N_3 PF13417.6 KXT03574.1 - 3e-21 75.6 0.0 6.8e-21 74.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXT03574.1 - 5.9e-15 55.3 0.0 1.1e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXT03574.1 - 2.3e-09 37.4 0.0 4.3e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXT03574.1 - 2.8e-08 33.7 0.1 5.3e-08 32.8 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KXT03574.1 - 3.6e-05 24.3 0.0 6.3e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Use1 PF09753.9 KXT03575.1 - 7.2e-09 35.7 11.3 1.4e-08 34.8 11.3 1.5 1 1 0 1 1 1 1 Membrane fusion protein Use1 CCDC84 PF14968.6 KXT03575.1 - 0.38 10.3 4.5 1.1 8.8 0.0 2.2 1 1 1 2 2 2 0 Coiled coil protein 84 zf-C2H2 PF00096.26 KXT03576.1 - 5.5e-07 29.7 7.1 3.1e-05 24.2 1.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXT03576.1 - 3.9e-05 23.9 2.4 3.9e-05 23.9 2.4 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 KXT03576.1 - 0.00074 19.4 0.2 0.0023 17.9 0.2 1.8 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KXT03576.1 - 0.011 16.5 0.8 0.011 16.5 0.8 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger DSBA PF01323.20 KXT03577.1 - 9.4e-23 81.0 0.0 1.1e-22 80.8 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain SinI PF08671.10 KXT03577.1 - 0.0058 16.4 0.1 0.012 15.4 0.1 1.5 1 0 0 1 1 1 1 Anti-repressor SinI Radical_SAM_C PF16199.5 KXT03577.1 - 0.17 12.0 0.3 18 5.4 0.0 2.7 3 0 0 3 3 3 0 Radical_SAM C-terminal domain Whi5 PF08528.11 KXT03579.1 - 4.4e-08 32.6 0.1 9.8e-08 31.5 0.1 1.6 1 0 0 1 1 1 1 Whi5 like ATP_bind_1 PF03029.17 KXT03580.1 - 2.3e-65 220.7 2.1 6.3e-64 216.1 0.5 2.5 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 KXT03580.1 - 4.1e-07 29.7 0.0 0.0047 16.5 0.2 3.0 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KXT03580.1 - 0.00018 22.0 0.1 0.0013 19.1 0.0 2.3 2 2 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KXT03580.1 - 0.00025 21.0 1.4 0.24 11.3 0.0 3.3 3 0 0 3 3 3 1 RsgA GTPase MeaB PF03308.16 KXT03580.1 - 0.00026 20.1 0.5 0.011 14.7 0.1 2.2 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Ras PF00071.22 KXT03580.1 - 0.00071 19.2 0.1 0.027 14.1 0.1 2.5 2 1 0 2 2 2 1 Ras family AAA_23 PF13476.6 KXT03580.1 - 0.0012 19.4 0.3 1.4 9.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KXT03580.1 - 0.0012 19.0 0.0 0.0076 16.3 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KXT03580.1 - 0.0017 18.7 0.0 0.012 15.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KXT03580.1 - 0.002 18.0 0.0 0.0062 16.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Roc PF08477.13 KXT03580.1 - 0.0029 17.8 0.1 0.55 10.5 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 KXT03580.1 - 0.0062 16.1 0.0 0.2 11.2 0.0 2.6 2 0 0 2 2 2 1 Ferrous iron transport protein B G-alpha PF00503.20 KXT03580.1 - 0.0067 15.6 5.7 0.0075 15.5 0.1 2.8 2 1 1 3 3 3 1 G-protein alpha subunit NB-ARC PF00931.22 KXT03580.1 - 0.0068 15.6 0.0 0.017 14.3 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA_30 PF13604.6 KXT03580.1 - 0.007 16.1 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 KXT03580.1 - 0.011 15.4 0.1 1.1 8.8 0.0 2.6 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 KXT03580.1 - 0.019 15.1 0.3 0.071 13.3 0.0 2.1 2 0 0 2 2 1 0 AAA domain SRP54 PF00448.22 KXT03580.1 - 0.024 14.3 0.0 0.094 12.3 0.0 2.0 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain Septin PF00735.18 KXT03580.1 - 0.043 13.1 0.3 0.11 11.8 0.0 1.8 2 0 0 2 2 2 0 Septin KAP_NTPase PF07693.14 KXT03580.1 - 0.051 12.8 0.1 0.14 11.3 0.1 1.8 1 1 0 1 1 1 0 KAP family P-loop domain AAA_7 PF12775.7 KXT03580.1 - 0.071 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region SRPRB PF09439.10 KXT03580.1 - 0.086 12.3 1.8 1.3 8.5 0.0 2.5 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit RNA_helicase PF00910.22 KXT03580.1 - 0.092 13.1 0.4 0.69 10.3 0.0 2.6 3 0 0 3 3 2 0 RNA helicase Mg_chelatase PF01078.21 KXT03580.1 - 0.092 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PduV-EutP PF10662.9 KXT03580.1 - 0.13 12.0 1.1 0.95 9.2 0.1 2.6 3 1 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation PI-PLC-X PF00388.19 KXT03581.1 - 3.4e-11 42.9 0.0 5e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Translin PF01997.16 KXT03582.1 - 1.1e-68 231.3 0.0 1.2e-68 231.1 0.0 1.0 1 0 0 1 1 1 1 Translin family Metallophos PF00149.28 KXT03583.1 - 7.4e-20 72.3 0.1 1.1e-19 71.8 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXT03583.1 - 2.2e-05 24.7 0.0 0.00016 21.9 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Epimerase_2 PF02350.19 KXT03583.1 - 0.16 10.8 0.0 0.26 10.1 0.0 1.2 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase Corona_S2 PF01601.16 KXT03584.1 - 0.005 15.4 7.4 0.0066 15.0 7.4 1.1 1 0 0 1 1 1 1 Coronavirus S2 glycoprotein NAD_binding_6 PF08030.12 KXT03585.1 - 2.4e-08 34.3 0.0 3.7e-07 30.4 0.0 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 KXT03585.1 - 0.0012 19.4 0.0 0.019 15.6 0.0 2.3 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Zn_clus PF00172.18 KXT03587.1 - 1.4e-09 37.9 8.8 2.7e-09 37.0 8.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXT03587.1 - 2.7e-09 36.4 1.8 6.4e-09 35.2 1.8 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Sacchrp_dh_C PF16653.5 KXT03587.1 - 0.14 12.2 0.0 0.81 9.7 0.0 1.9 1 1 0 2 2 2 0 Saccharopine dehydrogenase C-terminal domain Aa_trans PF01490.18 KXT03588.1 - 2.2e-20 72.8 6.8 2.5e-20 72.6 6.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KXT03588.1 - 1.1e-05 24.7 6.0 1.4e-05 24.4 6.0 1.1 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family YwiC PF14256.6 KXT03588.1 - 0.0029 17.9 1.9 0.0029 17.9 1.9 1.8 2 0 0 2 2 2 1 YwiC-like protein PalH PF08733.10 KXT03588.1 - 0.046 12.7 0.5 0.077 12.0 0.5 1.3 1 0 0 1 1 1 0 PalH/RIM21 Aa_trans PF01490.18 KXT03589.1 - 7e-16 57.9 13.0 8.5e-16 57.7 13.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ATP-synt_I PF03899.15 KXT03589.1 - 0.0074 16.6 4.3 0.0074 16.6 4.3 2.6 2 1 0 2 2 2 1 ATP synthase I chain PrgI PF12666.7 KXT03589.1 - 1.4 9.7 7.1 2.7 8.8 0.5 2.8 2 2 0 2 2 2 0 PrgI family protein Zn_clus PF00172.18 KXT03590.1 - 1.7e-05 24.8 7.2 2.9e-05 24.1 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cu-oxidase_2 PF07731.14 KXT03591.1 - 8.5e-22 77.4 8.5 1e-20 73.9 2.2 3.0 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KXT03591.1 - 7.5e-18 64.7 1.7 7.5e-18 64.7 1.7 2.0 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 KXT03591.1 - 8.6e-07 29.2 0.1 9.5e-05 22.6 0.1 2.7 2 0 0 2 2 2 2 Multicopper oxidase JAB PF01398.21 KXT03592.1 - 1.8e-07 31.1 0.0 4.4e-06 26.7 0.0 2.5 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF3523 PF12037.8 KXT03592.1 - 3 7.1 10.8 5.5 6.3 10.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) Fe-ADH PF00465.19 KXT03593.1 - 1e-76 258.2 0.3 1.2e-76 258.0 0.3 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KXT03593.1 - 2.5e-15 56.9 0.1 3.3e-15 56.5 0.1 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DNA_pol_A_exo1 PF01612.20 KXT03594.1 - 9.8e-15 54.7 0.0 1.6e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease IU_nuc_hydro PF01156.19 KXT03594.1 - 0.062 12.9 0.0 0.091 12.3 0.0 1.2 1 0 0 1 1 1 0 Inosine-uridine preferring nucleoside hydrolase Transp_cyt_pur PF02133.15 KXT03595.1 - 9.3e-146 486.1 36.6 1.1e-145 485.8 36.6 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Cpn60_TCP1 PF00118.24 KXT03597.1 - 2.3e-157 524.6 3.7 2.6e-157 524.4 3.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CPT PF07931.12 KXT03597.1 - 0.029 14.2 0.7 1.1 9.1 0.0 2.9 2 1 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein An_peroxidase PF03098.15 KXT03598.1 - 1e-38 133.3 0.1 3.9e-25 88.4 0.0 3.2 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 KXT03598.1 - 1.9e-07 30.2 0.0 3.2e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 DEAD PF00270.29 KXT03599.1 - 3.2e-47 160.6 0.0 9.6e-47 159.0 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXT03599.1 - 4.5e-25 88.1 0.0 9.4e-25 87.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXT03600.1 - 3.8e-47 160.3 0.0 1.1e-46 158.8 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXT03600.1 - 5.1e-25 88.0 0.0 1.1e-24 87.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Fungal_trans_2 PF11951.8 KXT03603.1 - 4.3e-49 167.4 4.5 4.3e-49 167.4 4.5 2.1 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT03603.1 - 1.8e-05 24.7 6.5 3.8e-05 23.7 6.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EthD PF07110.11 KXT03603.1 - 0.051 14.7 1.2 0.22 12.7 0.0 2.6 3 0 0 3 3 3 0 EthD domain Coatomer_E PF04733.14 KXT03604.1 - 2.6e-52 178.0 3.8 3e-52 177.8 3.8 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit ANAPC3 PF12895.7 KXT03604.1 - 5.3e-08 33.0 0.2 0.014 15.6 0.1 3.4 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 KXT03604.1 - 3e-06 26.8 0.0 0.0046 16.7 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXT03604.1 - 2e-05 25.0 16.7 0.0008 19.9 1.1 4.1 4 2 1 5 5 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXT03604.1 - 2.9e-05 23.8 7.8 0.00031 20.6 0.0 5.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.6 KXT03604.1 - 8.9e-05 23.0 11.8 0.014 16.1 0.2 5.6 4 2 2 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXT03604.1 - 0.00038 20.7 8.0 0.0064 16.8 0.5 3.9 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXT03604.1 - 0.0087 16.2 0.8 0.045 14.0 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXT03604.1 - 0.021 15.5 12.8 0.46 11.2 0.1 4.6 2 1 2 5 5 5 0 Tetratricopeptide repeat YfdX PF10938.8 KXT03604.1 - 0.1 12.6 3.8 1.2 9.0 0.3 3.0 3 1 0 3 3 3 0 YfdX protein TPR_4 PF07721.14 KXT03604.1 - 0.15 12.8 7.8 3.2 8.6 0.1 4.1 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXT03604.1 - 0.21 12.3 5.3 15 6.5 0.0 5.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_9 PF13371.6 KXT03604.1 - 0.24 11.6 2.3 1.4 9.1 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 KXT03604.1 - 0.59 9.9 0.0 0.59 9.9 0.0 2.9 4 0 0 4 4 4 0 TPR repeat adh_short PF00106.25 KXT03605.1 - 5.7e-11 42.2 0.0 8.2e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT03605.1 - 2.7e-09 36.9 0.0 5.7e-09 35.9 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Memo PF01875.17 KXT03606.1 - 2.6e-70 236.7 0.0 3.8e-70 236.1 0.0 1.2 1 0 0 1 1 1 1 Memo-like protein Memo PF01875.17 KXT03607.1 - 1.2e-10 41.0 0.0 2.3e-10 40.0 0.0 1.5 1 1 0 1 1 1 1 Memo-like protein Memo PF01875.17 KXT03608.1 - 2.6e-70 236.7 0.0 3.8e-70 236.1 0.0 1.2 1 0 0 1 1 1 1 Memo-like protein Kinesin PF00225.23 KXT03609.1 - 2.5e-111 371.8 0.0 2.5e-111 371.8 0.0 1.8 2 0 0 2 2 1 1 Kinesin motor domain DUF3694 PF12473.8 KXT03609.1 - 6e-43 147.2 0.1 2.1e-42 145.4 0.1 2.0 1 0 0 1 1 1 1 Kinesin protein Kinesin_assoc PF16183.5 KXT03609.1 - 8.6e-37 127.0 10.4 1.4e-29 103.5 0.2 3.6 2 1 1 3 3 3 2 Kinesin-associated Microtub_bd PF16796.5 KXT03609.1 - 3e-25 88.9 0.0 1e-24 87.1 0.0 2.0 1 0 0 1 1 1 1 Microtubule binding PH PF00169.29 KXT03609.1 - 0.0006 20.3 0.4 0.0068 16.9 0.1 2.5 2 0 0 2 2 2 1 PH domain KIF1B PF12423.8 KXT03609.1 - 0.01 16.2 0.4 0.01 16.2 0.4 3.1 5 0 0 5 5 1 0 Kinesin protein 1B UPF0242 PF06785.11 KXT03609.1 - 0.22 11.6 26.5 0.35 11.0 2.4 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4854 PF16146.5 KXT03609.1 - 0.59 10.5 13.5 0.042 14.2 6.8 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4854) FAM76 PF16046.5 KXT03609.1 - 0.65 9.3 16.0 0.064 12.6 8.1 2.3 2 0 0 2 2 2 0 FAM76 protein OmpH PF03938.14 KXT03609.1 - 0.76 10.1 29.6 0.24 11.7 21.1 2.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) AAA_22 PF13401.6 KXT03609.1 - 1.3 9.3 3.2 5.2 7.3 0.0 2.8 2 1 0 2 2 2 0 AAA domain DUF3819 PF12842.7 KXT03609.1 - 1.7 8.6 7.0 5.2 7.0 7.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3819) Borrelia_P83 PF05262.11 KXT03609.1 - 2 6.8 13.9 0.014 13.9 5.2 1.8 2 0 0 2 2 2 0 Borrelia P83/100 protein DLP_helical PF18709.1 KXT03609.1 - 3.2 6.9 19.5 0.23 10.6 11.4 3.0 3 1 0 3 3 3 0 Dynamin-like helical domain Exonuc_VII_L PF02601.15 KXT03609.1 - 7.2 6.1 17.8 6.9 6.1 12.0 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit CwfJ_C_1 PF04677.15 KXT03610.1 - 1.2e-26 93.0 0.1 2.2e-26 92.1 0.1 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 KXT03610.1 - 1.9e-25 89.6 0.3 1.9e-25 89.6 0.3 2.7 3 0 0 3 3 3 1 Protein similar to CwfJ C-terminus 2 Chromo PF00385.24 KXT03611.1 - 5.1e-13 48.7 1.3 5.1e-13 48.7 1.3 2.3 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 KXT03611.1 - 7.8e-10 38.7 5.8 2.4e-09 37.1 0.1 3.4 3 1 0 3 3 3 1 Chromo shadow domain Troponin-I_N PF11636.8 KXT03611.1 - 2.2 8.3 7.9 0.3 11.1 2.2 2.2 2 0 0 2 2 2 0 Troponin I residues 1-32 NAD_binding_6 PF08030.12 KXT03612.1 - 2.1e-20 73.4 0.0 1e-18 68.0 0.0 2.5 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KXT03612.1 - 1.1e-19 70.8 10.4 1.1e-19 70.8 10.4 2.7 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KXT03612.1 - 8.1e-12 45.2 0.0 3.9e-11 43.0 0.0 2.3 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KXT03612.1 - 4.2e-05 24.1 0.0 0.027 15.1 0.0 2.7 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain Met_10 PF02475.16 KXT03613.1 - 4e-68 229.1 0.0 5.6e-68 228.6 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein TRM PF02005.16 KXT03613.1 - 0.083 12.0 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase DUF2235 PF09994.9 KXT03614.1 - 2.7e-80 269.8 0.3 3.7e-80 269.3 0.3 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Translin PF01997.16 KXT03614.1 - 0.062 13.3 0.1 0.11 12.5 0.1 1.4 1 1 0 1 1 1 0 Translin family Amdase PF17645.1 KXT03616.1 - 1.8e-19 70.3 0.3 2.5e-19 69.8 0.3 1.1 1 0 0 1 1 1 1 Arylmalonate decarboxylase Asp_Glu_race PF01177.22 KXT03616.1 - 1.7e-08 34.6 0.9 2.6e-08 34.0 0.9 1.4 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase UEV PF05743.13 KXT03617.1 - 1.4e-33 115.4 0.0 2.4e-33 114.6 0.0 1.4 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 KXT03617.1 - 3.1e-21 75.1 0.9 8.7e-21 73.6 0.0 2.2 2 0 0 2 2 2 1 Vps23 core domain UQ_con PF00179.26 KXT03617.1 - 0.02 14.6 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme Paralemmin PF03285.15 KXT03617.1 - 0.044 13.4 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 Paralemmin CDH-cyt PF16010.5 KXT03618.1 - 5e-13 49.1 0.3 1e-12 48.1 0.3 1.4 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 KXT03618.1 - 1.4e-10 41.5 13.6 1.4e-10 41.5 13.6 3.0 4 0 0 4 4 4 1 Eukaryotic cytochrome b561 DOMON PF03351.17 KXT03618.1 - 3.6e-05 24.0 0.4 7.5e-05 22.9 0.4 1.5 1 0 0 1 1 1 1 DOMON domain DUF2427 PF10348.9 KXT03618.1 - 0.00012 21.8 4.8 0.00012 21.8 4.8 2.6 2 1 0 3 3 3 1 Domain of unknown function (DUF2427) DUF373 PF04123.13 KXT03618.1 - 0.17 11.3 10.0 0.42 10.0 10.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF373) DUF3007 PF11460.8 KXT03618.1 - 0.2 11.9 3.4 0.24 11.7 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3007) DUF998 PF06197.13 KXT03618.1 - 0.54 9.8 21.6 0.19 11.3 16.8 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF998) Acyl_transf_3 PF01757.22 KXT03618.1 - 2.1 7.4 22.6 3 6.8 14.7 2.6 2 1 0 2 2 2 0 Acyltransferase family DUF4229 PF14012.6 KXT03618.1 - 4.6 7.4 9.2 0.38 10.9 0.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) SET PF00856.28 KXT03619.1 - 5.2e-21 75.8 0.2 1.8e-20 74.0 0.2 2.0 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.16 KXT03619.1 - 1.1e-13 51.8 1.0 1.1e-13 51.8 1.0 2.3 2 1 0 2 2 2 1 Pre-SET motif Chromo PF00385.24 KXT03619.1 - 0.012 15.5 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain GTF2I PF02946.14 KXT03619.1 - 0.11 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 GTF2I-like repeat PIP5K PF01504.18 KXT03620.1 - 1.2e-50 172.3 0.0 4.5e-50 170.4 0.0 1.7 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Nop52 PF05997.12 KXT03621.1 - 6.9e-70 235.2 0.1 8.6e-70 234.9 0.1 1.0 1 0 0 1 1 1 1 Nucleolar protein,Nop52 RlaP PF10127.9 KXT03621.1 - 0.11 12.1 0.0 0.95 9.0 0.0 2.0 2 0 0 2 2 2 0 RNA repair pathway DNA polymerase beta family Abhydrolase_1 PF00561.20 KXT03642.1 - 2.6e-49 168.2 0.0 8.1e-49 166.6 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXT03642.1 - 0.00054 20.6 2.8 0.0014 19.3 2.8 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Say1_Mug180 PF10340.9 KXT03642.1 - 0.0015 17.5 0.0 0.0021 17.0 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 KXT03642.1 - 0.011 15.0 0.0 0.81 8.9 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 KXT03642.1 - 0.018 15.1 0.0 0.045 13.9 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein Peptidase_M14 PF00246.24 KXT03643.1 - 7.3e-70 236.0 0.0 1.2e-69 235.3 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase YTH PF04146.15 KXT03646.1 - 2.9e-14 53.4 0.8 7.8e-14 52.0 0.0 2.1 2 1 0 2 2 2 1 YT521-B-like domain Methyltransf_23 PF13489.6 KXT03647.1 - 0.00079 19.3 0.0 0.0018 18.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Spermine_synth PF01564.17 KXT03647.1 - 0.029 13.8 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 Spermine/spermidine synthase domain Vfa1 PF08432.10 KXT03648.1 - 2.5e-50 171.3 19.9 2.8e-50 171.1 19.9 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 CDO_I PF05995.12 KXT03648.1 - 0.081 12.2 0.0 0.17 11.2 0.0 1.5 1 1 0 1 1 1 0 Cysteine dioxygenase type I DUF262 PF03235.14 KXT03648.1 - 0.31 11.2 7.9 0.35 11.0 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 ColG_sub PF18496.1 KXT03648.1 - 1.7 8.8 6.0 2.6 8.2 6.0 1.2 1 0 0 1 1 1 0 Collagenase G catalytic helper subdomain Borrelia_P83 PF05262.11 KXT03648.1 - 1.8 7.0 23.2 2 6.8 23.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Neur_chan_memb PF02932.16 KXT03648.1 - 7 6.6 6.0 8.9 6.3 6.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Steroid_dh PF02544.16 KXT03649.1 - 7.1e-17 61.8 4.1 1.3e-16 60.9 0.4 2.5 2 2 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KXT03649.1 - 0.029 13.9 0.3 0.048 13.2 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) SRR1 PF07985.12 KXT03650.1 - 9.4e-07 28.8 0.0 1.7e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 SRR1 adh_short_C2 PF13561.6 KXT03651.1 - 5.4e-41 140.7 0.1 6.6e-41 140.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXT03651.1 - 1.8e-37 128.7 0.0 2.8e-37 128.1 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXT03651.1 - 2.7e-09 37.2 0.1 6.3e-09 36.0 0.0 1.5 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 KXT03651.1 - 0.0044 16.2 0.0 0.0061 15.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NPV_P10 PF05531.12 KXT03652.1 - 0.0029 18.0 2.3 0.0035 17.8 2.3 1.1 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein ABC_tran_CTD PF16326.5 KXT03652.1 - 0.0086 16.3 0.3 0.01 16.1 0.3 1.1 1 0 0 1 1 1 1 ABC transporter C-terminal domain FliS PF02561.14 KXT03652.1 - 0.046 14.0 0.2 0.05 13.9 0.2 1.1 1 0 0 1 1 1 0 Flagellar protein FliS PPR_2 PF13041.6 KXT03653.1 - 1e-23 83.3 0.3 4.6e-13 49.1 0.0 4.2 4 1 1 5 5 5 3 PPR repeat family PPR_1 PF12854.7 KXT03653.1 - 1.4e-16 59.9 0.0 1.4e-05 24.6 0.0 4.0 4 0 0 4 4 4 3 PPR repeat PPR_3 PF13812.6 KXT03653.1 - 6.4e-13 48.6 0.5 5.5e-09 36.0 0.0 3.2 3 1 0 3 3 3 2 Pentatricopeptide repeat domain PPR PF01535.20 KXT03653.1 - 9.7e-13 47.4 0.1 0.00037 20.6 0.0 4.3 4 0 0 4 4 4 2 PPR repeat PPR_long PF17177.4 KXT03653.1 - 1.4e-07 31.1 0.7 0.017 14.5 0.1 2.7 2 1 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP RRM_1 PF00076.22 KXT03655.1 - 2.1e-17 62.7 0.0 4.9e-17 61.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 KXT03655.1 - 0.0023 18.5 13.2 0.0023 18.5 13.2 3.9 4 2 0 4 4 4 1 C-terminal duplication domain of Friend of PRMT1 ETF PF01012.21 KXT03656.1 - 3.9e-45 154.0 0.5 5.6e-45 153.5 0.5 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Chorismate_synt PF01264.21 KXT03657.1 - 7.6e-138 458.7 0.0 8.8e-138 458.5 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase DUF647 PF04884.14 KXT03658.1 - 3.7e-107 357.5 1.7 5.1e-107 357.0 1.7 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis DHquinase_I PF01487.15 KXT03659.1 - 5.6e-48 164.2 0.0 9.9e-48 163.4 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase DHquinase_I PF01487.15 KXT03660.1 - 5.6e-48 164.2 0.0 9.9e-48 163.4 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase Ctr PF04145.15 KXT03661.1 - 2.7e-28 99.5 2.8 5e-28 98.6 2.8 1.4 1 1 0 1 1 1 1 Ctr copper transporter family MFS_1 PF07690.16 KXT03662.1 - 1.6e-27 96.3 26.1 1.6e-27 96.3 26.1 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXT03662.1 - 9.9e-05 21.4 11.5 9.9e-05 21.4 11.5 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter Flavodoxin_1 PF00258.25 KXT03663.1 - 1.2e-27 96.9 0.0 2.7e-27 95.7 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.20 KXT03663.1 - 1.2e-23 83.9 0.0 1.9e-23 83.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KXT03663.1 - 1.4e-15 57.9 0.0 1.4e-14 54.6 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KXT03663.1 - 0.13 12.5 0.0 1 9.6 0.0 2.3 2 1 0 2 2 2 0 Flavodoxin domain ThrE PF06738.12 KXT03665.1 - 3.9e-61 206.5 25.0 5.8e-61 205.9 2.1 2.4 3 0 0 3 3 3 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KXT03665.1 - 1.9e-09 37.7 15.4 1.9e-09 37.7 15.4 2.7 2 1 0 2 2 2 1 Threonine/Serine exporter, ThrE Sec7 PF01369.20 KXT03666.1 - 4.2e-31 108.0 0.0 7.2e-31 107.3 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 KXT03666.1 - 3.5e-07 30.6 0.2 9.7e-07 29.2 0.2 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KXT03666.1 - 4.3e-06 27.2 0.0 1.3e-05 25.6 0.0 1.9 1 0 0 1 1 1 1 PH domain Pkinase PF00069.25 KXT03667.1 - 8.9e-49 166.2 0.0 3e-34 118.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXT03667.1 - 6.3e-21 74.8 0.0 3.7e-19 69.0 0.0 3.2 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KXT03667.1 - 4.4e-06 26.2 0.0 1.3e-05 24.7 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KXT03667.1 - 0.01 15.8 0.1 0.16 11.9 0.0 2.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Ldl_recept_b PF00058.17 KXT03668.1 - 2.2e-07 31.2 0.9 0.00064 20.1 0.0 5.0 6 0 0 6 6 6 1 Low-density lipoprotein receptor repeat class B SGL PF08450.12 KXT03668.1 - 0.00083 19.0 0.0 2.6 7.6 0.0 3.3 3 0 0 3 3 3 3 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 KXT03668.1 - 0.017 15.2 0.0 0.47 10.6 0.0 3.1 4 0 0 4 4 4 0 Strictosidine synthase PAS_8 PF13188.7 KXT03668.1 - 0.099 12.7 0.0 3.6 7.7 0.0 2.4 2 0 0 2 2 2 0 PAS domain CTK3 PF12243.8 KXT03669.1 - 5.5e-44 149.1 0.0 7.7e-44 148.6 0.0 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 KXT03669.1 - 1.5e-24 85.9 10.4 3.4e-24 84.8 10.4 1.6 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus KfrA_N PF11740.8 KXT03669.1 - 0.39 11.4 6.2 2.8 8.7 1.9 2.5 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term Haspin_kinase PF12330.8 KXT03670.1 - 4.4e-43 147.6 0.0 6.2e-43 147.1 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain tRNA-synt_1g PF09334.11 KXT03671.1 - 4.9e-153 509.5 0.2 1.1e-152 508.3 0.1 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KXT03671.1 - 3.8e-08 32.0 0.2 2.7e-05 22.6 0.0 3.2 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KXT03671.1 - 0.0012 18.8 1.2 0.002 18.1 0.5 1.7 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA HNOBA PF07701.14 KXT03671.1 - 0.087 12.2 0.1 4.1 6.8 0.0 2.2 2 0 0 2 2 2 0 Heme NO binding associated Isochorismatase PF00857.20 KXT03672.1 - 8.4e-45 153.1 0.0 1e-44 152.8 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family MFS_1 PF07690.16 KXT03673.1 - 2e-12 46.7 13.3 2.7e-12 46.3 13.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXT03673.1 - 2.3e-06 26.8 4.1 4e-06 25.9 3.8 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.6 KXT03673.1 - 0.0002 20.1 1.6 0.00033 19.4 1.5 1.5 1 1 0 1 1 1 1 MFS/sugar transport protein TRI12 PF06609.13 KXT03673.1 - 0.0024 16.3 0.2 0.0032 15.9 0.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) CclA_1 PF16942.5 KXT03673.1 - 0.2 11.9 4.9 0.66 10.3 0.2 2.5 1 1 0 2 2 2 0 Putative cyclic bacteriocin Isochorismatase PF00857.20 KXT03674.1 - 8.4e-45 153.1 0.0 1e-44 152.8 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family MFS_1 PF07690.16 KXT03675.1 - 2e-12 46.7 13.3 2.7e-12 46.3 13.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXT03675.1 - 2.3e-06 26.8 4.1 4e-06 25.9 3.8 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.6 KXT03675.1 - 0.0002 20.1 1.6 0.00033 19.4 1.5 1.5 1 1 0 1 1 1 1 MFS/sugar transport protein TRI12 PF06609.13 KXT03675.1 - 0.0024 16.3 0.2 0.0032 15.9 0.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) CclA_1 PF16942.5 KXT03675.1 - 0.2 11.9 4.9 0.66 10.3 0.2 2.5 1 1 0 2 2 2 0 Putative cyclic bacteriocin Nucleos_tra2_C PF07662.13 KXT03676.1 - 0.022 14.6 0.7 0.028 14.2 0.7 1.1 1 0 0 1 1 1 0 Na+ dependent nucleoside transporter C-terminus BTB PF00651.31 KXT03677.1 - 7.7e-16 58.3 0.0 8.9e-16 58.1 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KXT03678.1 - 8.3e-11 42.1 0.4 1.7e-10 41.1 0.4 1.5 1 0 0 1 1 1 1 BTB/POZ domain Fungal_trans PF04082.18 KXT03679.1 - 1.9e-20 73.1 0.0 4.6e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT03679.1 - 7.3e-06 26.0 16.9 1.4e-05 25.1 16.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RP-C_C PF11800.8 KXT03679.1 - 0.11 12.6 0.1 0.11 12.6 0.1 1.6 2 0 0 2 2 2 0 Replication protein C C-terminal region Striatin PF08232.12 KXT03679.1 - 0.26 11.9 1.2 0.38 11.3 0.1 1.8 2 0 0 2 2 2 0 Striatin family Zn_clus PF00172.18 KXT03680.1 - 1.6e-09 37.7 5.6 2.6e-09 37.0 5.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXT03680.1 - 0.0006 18.7 0.2 0.00087 18.2 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ras PF00071.22 KXT03681.1 - 2.1e-55 186.8 0.0 2.4e-55 186.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXT03681.1 - 6.9e-22 77.9 0.0 1.1e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXT03681.1 - 5.3e-07 29.3 0.0 8.6e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KXT03681.1 - 0.0022 17.4 0.0 0.0038 16.7 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit NB-ARC PF00931.22 KXT03681.1 - 0.032 13.4 0.1 0.31 10.2 0.0 2.0 1 1 1 2 2 2 0 NB-ARC domain PduV-EutP PF10662.9 KXT03681.1 - 0.035 13.9 0.1 4.9 6.9 0.0 2.5 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 KXT03681.1 - 0.092 12.1 0.0 0.13 11.6 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Ras PF00071.22 KXT03682.1 - 2.1e-55 186.8 0.0 2.4e-55 186.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXT03682.1 - 6.9e-22 77.9 0.0 1.1e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXT03682.1 - 5.3e-07 29.3 0.0 8.6e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KXT03682.1 - 0.0022 17.4 0.0 0.0038 16.7 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit NB-ARC PF00931.22 KXT03682.1 - 0.032 13.4 0.1 0.31 10.2 0.0 2.0 1 1 1 2 2 2 0 NB-ARC domain PduV-EutP PF10662.9 KXT03682.1 - 0.035 13.9 0.1 4.9 6.9 0.0 2.5 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 KXT03682.1 - 0.092 12.1 0.0 0.13 11.6 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Ras PF00071.22 KXT03683.1 - 5e-55 185.5 0.0 6.1e-55 185.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXT03683.1 - 1.4e-21 76.9 0.0 2.3e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXT03683.1 - 9.7e-07 28.4 0.0 1.6e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KXT03683.1 - 0.0049 16.3 0.0 0.0078 15.7 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit NB-ARC PF00931.22 KXT03683.1 - 0.061 12.5 0.1 0.59 9.3 0.0 2.0 1 1 1 2 2 2 0 NB-ARC domain PduV-EutP PF10662.9 KXT03683.1 - 0.085 12.6 0.1 6 6.6 0.0 2.4 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 KXT03683.1 - 0.18 11.1 0.0 0.28 10.5 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Sugar_tr PF00083.24 KXT03684.1 - 1.6e-45 155.8 9.4 2.3e-45 155.3 9.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXT03684.1 - 5.7e-36 124.2 25.9 5.7e-36 124.2 25.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily ATG22 PF11700.8 KXT03684.1 - 3.7e-06 25.9 2.4 7.7e-05 21.5 0.2 2.3 2 0 0 2 2 2 2 Vacuole effluxer Atg22 like MFS_1_like PF12832.7 KXT03684.1 - 2e-05 23.6 3.0 0.00049 19.1 0.0 2.7 2 2 0 2 2 2 1 MFS_1 like family UNC-93 PF05978.16 KXT03684.1 - 0.14 11.9 2.0 0.17 11.6 0.6 1.9 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 UPF0016 PF01169.19 KXT03684.1 - 0.22 11.9 0.1 0.22 11.9 0.1 4.0 5 0 0 5 5 5 0 Uncharacterized protein family UPF0016 FUSC_2 PF13515.6 KXT03684.1 - 0.52 10.4 0.0 0.52 10.4 0.0 3.9 4 2 0 4 4 4 0 Fusaric acid resistance protein-like LacY_symp PF01306.19 KXT03684.1 - 4.8 5.8 9.8 0.17 10.6 1.4 2.3 1 1 1 2 2 2 0 LacY proton/sugar symporter OATP PF03137.20 KXT03684.1 - 6.5 4.9 10.8 1.1 7.5 5.8 2.1 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family BT1 PF03092.16 KXT03684.1 - 8.4 4.5 9.6 2.6 6.2 2.3 3.0 2 1 2 4 4 4 0 BT1 family OCD_Mu_crystall PF02423.15 KXT03685.1 - 1.8e-09 37.0 0.1 0.00041 19.4 0.0 3.3 4 0 0 4 4 4 2 Ornithine cyclodeaminase/mu-crystallin family MPDZ_u10 PF16667.5 KXT03685.1 - 0.23 12.4 1.8 0.32 11.9 0.0 2.1 2 0 0 2 2 2 0 Unstructured region 10 on multiple PDZ protein UBA2_C PF16195.5 KXT03687.1 - 0.72 10.6 4.3 1.4 9.6 4.3 1.5 1 1 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus 3HCDH_N PF02737.18 KXT03688.1 - 2.4e-40 138.3 0.0 3.7e-40 137.7 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KXT03688.1 - 2.7e-11 43.9 0.0 4.7e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_7 PF13241.6 KXT03688.1 - 0.0042 17.5 0.0 0.0079 16.6 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 KXT03688.1 - 0.0051 16.2 0.0 0.0088 15.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KXT03688.1 - 0.02 15.4 0.0 0.058 14.0 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.14 KXT03688.1 - 0.046 13.3 0.0 0.1 12.2 0.0 1.6 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.15 KXT03688.1 - 0.06 13.5 0.0 0.13 12.4 0.0 1.6 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.21 KXT03688.1 - 0.069 12.4 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KXT03688.1 - 0.088 13.4 0.0 0.2 12.2 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F-box PF00646.33 KXT03691.1 - 0.001 18.9 0.0 0.0071 16.2 0.0 2.4 3 0 0 3 3 3 1 F-box domain DUF3584 PF12128.8 KXT03692.1 - 0.031 11.8 6.3 0.041 11.4 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DLP_helical PF18709.1 KXT03692.1 - 0.057 12.6 2.8 0.097 11.9 2.8 1.4 1 0 0 1 1 1 0 Dynamin-like helical domain Golgin_A5 PF09787.9 KXT03692.1 - 0.19 11.2 6.4 0.097 12.1 4.3 1.6 2 0 0 2 2 2 0 Golgin subfamily A member 5 Syntaxin PF00804.25 KXT03692.1 - 0.23 11.1 6.5 0.7 9.5 0.8 2.2 1 1 1 2 2 2 0 Syntaxin Prominin PF05478.11 KXT03692.1 - 0.63 7.9 2.0 0.81 7.6 2.0 1.1 1 0 0 1 1 1 0 Prominin Lectin_N PF03954.14 KXT03692.1 - 1.2 8.9 3.6 1.3 8.7 1.2 2.1 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain Fib_alpha PF08702.10 KXT03692.1 - 1.3 9.2 4.5 5.1 7.3 1.9 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF883 PF05957.13 KXT03692.1 - 4.8 7.8 6.4 1.6 9.4 0.8 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DSPc PF00782.20 KXT03695.1 - 9.1e-26 90.2 0.0 1.3e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KXT03695.1 - 0.091 12.7 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family ANTAR PF03861.14 KXT03695.1 - 0.12 12.3 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 ANTAR domain Yippee-Mis18 PF03226.14 KXT03695.1 - 0.22 11.8 1.9 0.98 9.7 1.9 2.0 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DSPc PF00782.20 KXT03696.1 - 3.1e-10 40.0 0.0 4.7e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain ANTAR PF03861.14 KXT03696.1 - 0.08 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 ANTAR domain zf-LITAF-like PF10601.9 KXT03696.1 - 0.084 13.1 0.6 17 5.8 0.1 2.7 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain Yippee-Mis18 PF03226.14 KXT03696.1 - 0.15 12.2 2.4 0.72 10.1 2.4 2.0 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DSPc PF00782.20 KXT03697.1 - 1.4e-06 28.1 0.0 1.7e-06 27.9 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CoA_transf_3 PF02515.17 KXT03698.1 - 1.2e-38 133.2 0.1 8.5e-37 127.1 0.1 2.2 2 0 0 2 2 2 2 CoA-transferase family III RRM_1 PF00076.22 KXT03699.1 - 2.1e-15 56.3 0.0 3.4e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3450 PF11932.8 KXT03699.1 - 0.12 11.7 3.4 0.15 11.3 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) UPF0242 PF06785.11 KXT03699.1 - 0.18 11.9 4.9 0.25 11.4 4.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4140 PF13600.6 KXT03699.1 - 0.35 11.3 1.9 0.6 10.6 1.9 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) EMP24_GP25L PF01105.24 KXT03699.1 - 0.7 9.8 2.3 0.98 9.3 2.3 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD TRAP_alpha PF03896.16 KXT03699.1 - 1.7 7.8 4.1 2.6 7.2 4.1 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF724 PF05266.14 KXT03699.1 - 3.6 7.4 6.9 5 6.9 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) MFS_1 PF07690.16 KXT03700.1 - 2.4e-30 105.6 42.0 2.4e-29 102.4 34.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_25 PF01183.20 KXT03701.1 - 1.7e-35 122.8 0.5 2.5e-35 122.3 0.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 RRM_1 PF00076.22 KXT03701.1 - 5.4e-15 55.0 0.0 9.8e-15 54.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UPF0242 PF06785.11 KXT03701.1 - 0.066 13.3 2.1 0.099 12.7 2.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Dynactin_p62 PF05502.13 KXT03701.1 - 0.18 10.5 0.3 0.24 10.1 0.3 1.1 1 0 0 1 1 1 0 Dynactin p62 family DUF4140 PF13600.6 KXT03701.1 - 1 9.9 2.9 1.7 9.1 2.9 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF3450 PF11932.8 KXT03701.1 - 1.5 8.1 5.7 2.1 7.6 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) MFS_1 PF07690.16 KXT03702.1 - 2.4e-30 105.6 42.0 2.4e-29 102.4 34.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily RRM_1 PF00076.22 KXT03703.1 - 2.1e-15 56.3 0.0 3.4e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3450 PF11932.8 KXT03703.1 - 0.12 11.7 3.4 0.15 11.3 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) UPF0242 PF06785.11 KXT03703.1 - 0.18 11.9 4.9 0.25 11.4 4.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4140 PF13600.6 KXT03703.1 - 0.35 11.3 1.9 0.6 10.6 1.9 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) EMP24_GP25L PF01105.24 KXT03703.1 - 0.7 9.8 2.3 0.98 9.3 2.3 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD TRAP_alpha PF03896.16 KXT03703.1 - 1.7 7.8 4.1 2.6 7.2 4.1 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF724 PF05266.14 KXT03703.1 - 3.6 7.4 6.9 5 6.9 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Y_phosphatase2 PF03162.13 KXT03704.1 - 3.1e-41 140.7 0.0 4.2e-41 140.3 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 KXT03704.1 - 6.4e-08 32.9 0.0 1.2e-07 32.0 0.0 1.4 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 KXT03704.1 - 6.1e-05 22.8 0.0 0.0001 22.2 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KXT03704.1 - 0.00049 19.7 0.0 0.00074 19.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PBECR3 PF18812.1 KXT03704.1 - 0.045 13.7 0.0 0.094 12.7 0.0 1.5 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease3 Y_phosphatase2 PF03162.13 KXT03705.1 - 3.1e-41 140.7 0.0 4.2e-41 140.3 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 KXT03705.1 - 6.4e-08 32.9 0.0 1.2e-07 32.0 0.0 1.4 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 KXT03705.1 - 6.1e-05 22.8 0.0 0.0001 22.2 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KXT03705.1 - 0.00049 19.7 0.0 0.00074 19.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PBECR3 PF18812.1 KXT03705.1 - 0.045 13.7 0.0 0.094 12.7 0.0 1.5 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease3 HORMA PF02301.18 KXT03706.1 - 4.1e-38 131.1 0.0 6.5e-38 130.5 0.0 1.3 1 0 0 1 1 1 1 HORMA domain PHD PF00628.29 KXT03706.1 - 0.00012 21.9 9.7 0.00022 21.1 9.7 1.4 1 0 0 1 1 1 1 PHD-finger Iso_dh PF00180.20 KXT03707.1 - 3.4e-90 302.7 0.0 3.8e-90 302.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF4875 PF16175.5 KXT03707.1 - 0.052 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4875) cwf18 PF08315.12 KXT03708.1 - 4.9e-44 150.3 13.9 4.9e-44 150.3 13.9 1.9 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor zf-C2H2 PF00096.26 KXT03709.1 - 0.0016 18.8 19.3 0.023 15.2 0.8 4.8 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXT03709.1 - 0.015 15.7 0.5 0.015 15.7 0.5 3.8 5 0 0 5 5 5 0 Zinc-finger double domain Ytp1 PF10355.9 KXT03709.1 - 0.26 10.5 0.1 0.58 9.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (Ytp1) zf-CHCC PF10276.9 KXT03709.1 - 0.36 10.9 3.3 5.9 7.0 0.3 2.4 2 0 0 2 2 2 0 Zinc-finger domain PyrI_C PF02748.15 KXT03709.1 - 0.5 10.3 6.2 6.2 6.8 0.0 2.4 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_4 PF13894.6 KXT03709.1 - 0.87 10.6 21.8 1.8 9.6 1.2 4.9 4 0 0 4 4 4 0 C2H2-type zinc finger HsbA PF12296.8 KXT03710.1 - 3.7e-19 69.3 3.4 4.5e-19 69.0 2.8 1.4 2 0 0 2 2 2 1 Hydrophobic surface binding protein A Shikimate_DH PF01488.20 KXT03711.1 - 2.2e-08 34.2 0.1 3.3e-07 30.5 0.1 2.6 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase OCD_Mu_crystall PF02423.15 KXT03711.1 - 2.8e-08 33.1 0.1 1.1e-05 24.6 0.0 2.6 2 1 0 2 2 2 2 Ornithine cyclodeaminase/mu-crystallin family GFO_IDH_MocA PF01408.22 KXT03711.1 - 0.069 14.0 0.0 0.13 13.0 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Sugar_tr PF00083.24 KXT03712.1 - 0.019 13.8 0.1 0.029 13.2 0.1 1.2 1 0 0 1 1 1 0 Sugar (and other) transporter MAPEG PF01124.18 KXT03713.1 - 4.4e-19 68.7 0.9 5.2e-19 68.4 0.9 1.0 1 0 0 1 1 1 1 MAPEG family Amidase PF01425.21 KXT03715.1 - 1.1e-48 166.4 1.8 2.9e-44 151.8 0.1 2.8 3 1 0 3 3 3 2 Amidase DDE_Tnp_1 PF01609.21 KXT03716.1 - 0.061 13.0 0.0 0.079 12.6 0.0 1.1 1 0 0 1 1 1 0 Transposase DDE domain Peptidase_M48 PF01435.18 KXT03717.1 - 6.3e-35 120.7 0.1 2.3e-34 118.9 0.1 1.8 1 1 0 1 1 1 1 Peptidase family M48 Zincin_1 PF06262.11 KXT03717.1 - 0.071 13.2 0.1 0.15 12.2 0.1 1.6 1 1 0 1 1 1 0 Zincin-like metallopeptidase RRM_1 PF00076.22 KXT03719.1 - 6.9e-29 99.5 0.1 5.7e-15 54.9 0.0 3.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXT03719.1 - 0.00019 21.0 0.0 0.078 12.6 0.0 3.2 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXT03719.1 - 0.0044 17.1 0.0 0.54 10.4 0.0 2.7 2 1 0 2 2 2 1 RNA recognition motif DbpA PF03880.15 KXT03719.1 - 0.021 14.8 0.0 5 7.2 0.0 2.4 2 0 0 2 2 2 0 DbpA RNA binding domain PHM7_cyt PF14703.6 KXT03719.1 - 0.059 13.6 0.1 36 4.5 0.0 3.1 2 1 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Limkain-b1 PF11608.8 KXT03719.1 - 0.065 13.3 0.1 21 5.3 0.0 2.7 3 0 0 3 3 3 0 Limkain b1 Tristanin_u2 PF16638.5 KXT03719.1 - 0.52 11.1 9.8 4.4 8.2 5.9 2.8 2 0 0 2 2 2 0 Unstructured region on methyltransferase between zinc-fingers Ferric_reduct PF01794.19 KXT03720.1 - 2.5e-21 76.1 11.9 2.5e-21 76.1 11.9 3.0 2 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KXT03720.1 - 4.3e-15 56.2 0.0 7.9e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KXT03720.1 - 1.2e-12 47.8 0.0 3.9e-12 46.2 0.0 1.9 2 0 0 2 2 2 1 FAD-binding domain DUF4405 PF14358.6 KXT03720.1 - 0.079 13.5 13.7 0.13 12.9 0.6 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) PHD PF00628.29 KXT03721.1 - 7.8e-11 41.7 1.2 1.9e-10 40.5 1.2 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KXT03721.1 - 0.0028 17.2 3.9 0.0048 16.4 3.9 1.3 1 0 0 1 1 1 1 PHD-finger UIM PF02809.20 KXT03721.1 - 0.24 11.4 3.8 0.64 10.1 3.8 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif DUF3678 PF12435.8 KXT03721.1 - 0.39 10.1 1.8 0.86 9.0 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) Pkinase PF00069.25 KXT03722.1 - 6.5e-48 163.4 0.0 9.7e-48 162.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT03722.1 - 1.9e-27 96.2 0.0 2.9e-26 92.3 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXT03722.1 - 0.004 16.5 0.2 0.012 15.0 0.0 1.8 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.14 KXT03722.1 - 0.0056 16.1 0.0 0.0094 15.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FAM217 PF15344.6 KXT03722.1 - 0.03 14.3 14.2 0.96 9.3 0.1 2.4 1 1 1 2 2 2 0 FAM217 family DUF2076 PF09849.9 KXT03722.1 - 0.039 14.0 5.6 0.09 12.8 5.6 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) SOG2 PF10428.9 KXT03722.1 - 3.2 6.8 11.1 4.7 6.3 11.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Lyase_1 PF00206.20 KXT03723.1 - 2.7e-94 316.1 0.0 3.6e-94 315.7 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 KXT03723.1 - 4.9e-24 84.9 0.0 1e-23 83.8 0.0 1.6 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal TauD PF02668.16 KXT03728.1 - 2e-44 152.4 0.1 2.6e-44 152.0 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TauD PF02668.16 KXT03729.1 - 2e-44 152.4 0.1 2.6e-44 152.0 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Glyco_hydro_5_C PF18564.1 KXT03730.1 - 3.4e-24 85.2 0.2 1.8e-23 82.9 0.1 2.3 2 0 0 2 2 2 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 KXT03730.1 - 2.4e-08 33.8 7.2 6.1e-07 29.2 0.8 3.4 3 1 0 3 3 3 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_35 PF01301.19 KXT03730.1 - 0.023 14.3 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 EKLF_TAD1 PF16832.5 KXT03730.1 - 0.089 12.7 0.7 0.23 11.4 0.7 1.7 1 0 0 1 1 1 0 Erythroid krueppel-like transcription factor, transactivation 1 p47_phox_C PF08944.11 KXT03730.1 - 0.22 10.9 1.1 0.68 9.4 1.1 1.8 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain Complex1_LYR_2 PF13233.6 KXT03732.1 - 3.5e-20 72.5 0.0 5.8e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KXT03732.1 - 4.1e-11 42.7 0.0 7.9e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 KXT03732.1 - 0.0048 17.5 0.0 0.0094 16.5 0.0 1.5 1 0 0 1 1 1 1 Complex1_LYR-like Thioredoxin PF00085.20 KXT03732.1 - 0.14 12.2 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin PCMT PF01135.19 KXT03735.1 - 4.2e-58 196.6 0.0 6.3e-58 196.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) HET PF06985.11 KXT03735.1 - 1.1e-12 48.5 5.5 4.6e-08 33.5 0.1 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Methyltransf_31 PF13847.6 KXT03735.1 - 2.1e-05 24.4 0.0 4.3e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KXT03735.1 - 0.0015 18.5 0.0 0.0037 17.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXT03735.1 - 0.0032 18.1 0.0 0.0077 16.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXT03735.1 - 0.004 17.0 0.0 0.01 15.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KXT03735.1 - 0.025 14.2 0.0 0.046 13.3 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW RrnaAD PF00398.20 KXT03735.1 - 0.052 12.6 0.0 0.084 11.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase adh_short PF00106.25 KXT03737.1 - 4.5e-33 114.4 0.0 6.4e-33 113.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT03737.1 - 2.7e-27 95.9 0.0 3.7e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Sacchrp_dh_NADP PF03435.18 KXT03737.1 - 2.9e-05 24.3 0.0 5.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 KXT03737.1 - 0.00012 22.0 0.0 0.00026 21.0 0.0 1.5 1 0 0 1 1 1 1 KR domain TrkA_N PF02254.18 KXT03737.1 - 0.00091 19.5 0.0 0.0017 18.6 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_10 PF13460.6 KXT03737.1 - 0.0026 17.7 0.0 0.0039 17.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 KXT03737.1 - 0.014 15.4 0.0 0.021 14.9 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Methyltransf_12 PF08242.12 KXT03737.1 - 0.054 14.2 0.0 0.12 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KXT03737.1 - 0.069 13.9 0.1 0.17 12.6 0.0 1.7 2 0 0 2 2 1 0 Methyltransferase domain NAD_binding_2 PF03446.15 KXT03737.1 - 0.11 12.7 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KXT03737.1 - 0.15 11.9 0.2 0.3 11.0 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Peptidase_C2 PF00648.21 KXT03738.1 - 2.8e-26 92.3 0.0 3.3e-25 88.7 0.0 2.1 1 1 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 KXT03738.1 - 4.5e-08 33.5 0.3 7.7e-06 26.2 0.0 3.3 3 1 0 3 3 3 1 Calpain large subunit, domain III Peptidase_C2 PF00648.21 KXT03739.1 - 2.8e-26 92.3 0.0 3.3e-25 88.7 0.0 2.1 1 1 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 KXT03739.1 - 4.5e-08 33.5 0.3 7.7e-06 26.2 0.0 3.3 3 1 0 3 3 3 1 Calpain large subunit, domain III Penicillinase_R PF03965.16 KXT03740.1 - 0.13 12.6 0.1 0.28 11.6 0.1 1.5 1 0 0 1 1 1 0 Penicillinase repressor SnoaL PF07366.12 KXT03741.1 - 0.0015 18.3 0.2 0.0023 17.7 0.2 1.2 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KXT03741.1 - 0.01 16.4 0.3 0.015 15.9 0.3 1.3 1 0 0 1 1 1 0 SnoaL-like domain SnoaL_3 PF13474.6 KXT03741.1 - 0.061 13.6 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain Aconitase_C PF00694.19 KXT03742.1 - 9.3e-46 155.4 0.0 1.2e-45 155.1 0.0 1.1 1 0 0 1 1 1 1 Aconitase C-terminal domain Aconitase_C PF00694.19 KXT03743.1 - 9.2e-46 155.4 0.0 1.2e-45 155.1 0.0 1.1 1 0 0 1 1 1 1 Aconitase C-terminal domain Aconitase PF00330.20 KXT03744.1 - 2.9e-136 455.1 0.0 3.8e-136 454.8 0.0 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) DUF521 PF04412.13 KXT03744.1 - 0.12 11.1 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Aconitase PF00330.20 KXT03745.1 - 7.1e-150 500.0 0.0 8.5e-150 499.8 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) DUF521 PF04412.13 KXT03745.1 - 0.13 10.9 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Hexapep PF00132.24 KXT03746.1 - 6.1e-06 25.8 5.1 0.0088 15.7 0.4 3.1 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KXT03746.1 - 0.00021 20.9 0.6 0.048 13.4 0.0 2.4 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase GST_N_3 PF13417.6 KXT03747.1 - 5.3e-21 74.8 0.0 9.8e-21 74.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXT03747.1 - 1.2e-19 70.4 0.0 2.3e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXT03747.1 - 3.8e-14 52.8 0.1 6.2e-14 52.1 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXT03747.1 - 6.5e-07 29.3 0.5 2e-06 27.7 0.3 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KXT03747.1 - 0.0019 18.9 0.0 0.0035 18.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain Glutaredoxin PF00462.24 KXT03747.1 - 0.0026 17.9 0.0 0.0046 17.1 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin CAP18_C PF12153.8 KXT03747.1 - 0.076 12.9 2.0 0.18 11.7 2.0 1.6 1 0 0 1 1 1 0 LPS binding domain of CAP18 (C terminal) TetR_C_24 PF17932.1 KXT03747.1 - 0.09 13.1 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain IBN_N PF03810.19 KXT03748.1 - 3.5e-05 23.6 0.2 0.0003 20.7 0.1 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain NUC153 PF08159.12 KXT03750.1 - 0.039 13.8 0.2 7.3 6.5 0.0 2.5 2 0 0 2 2 2 0 NUC153 domain Macscav_rec PF03523.13 KXT03750.1 - 0.11 12.4 2.7 1 9.3 0.8 2.3 2 0 0 2 2 2 0 Macrophage scavenger receptor adh_short PF00106.25 KXT03751.1 - 1.3e-25 90.0 0.0 1.6e-25 89.7 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT03751.1 - 7.4e-17 61.7 0.0 9.6e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT03751.1 - 0.0019 18.1 0.1 0.0027 17.6 0.1 1.2 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 KXT03751.1 - 0.002 18.2 0.0 0.0028 17.7 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Glyco_trans_4_2 PF13477.6 KXT03751.1 - 0.01 15.9 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase 4-like NAD_binding_2 PF03446.15 KXT03751.1 - 0.019 15.2 0.0 0.031 14.4 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Epimerase PF01370.21 KXT03751.1 - 0.027 13.9 0.0 0.037 13.5 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DFP PF04127.15 KXT03751.1 - 0.11 12.4 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein zf-C2H2 PF00096.26 KXT03752.1 - 0.0053 17.1 3.9 0.4 11.2 0.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXT03752.1 - 0.02 15.7 2.4 6.9 7.8 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-TFIIB PF13453.6 KXT03752.1 - 0.068 12.5 0.2 0.12 11.7 0.2 1.4 1 0 0 1 1 1 0 Transcription factor zinc-finger zf-TFIIB PF13453.6 KXT03753.1 - 0.071 12.5 0.2 0.13 11.6 0.2 1.4 1 0 0 1 1 1 0 Transcription factor zinc-finger zf-C2H2 PF00096.26 KXT03753.1 - 0.085 13.4 8.3 0.43 11.1 0.4 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXT03753.1 - 0.13 13.2 5.9 7.3 7.7 0.1 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger SET PF00856.28 KXT03755.1 - 4.1e-08 33.8 0.1 1.3e-07 32.2 0.1 1.9 1 1 0 1 1 1 1 SET domain Pico_P2B PF01552.17 KXT03756.1 - 0.11 12.7 0.1 2 8.6 0.0 2.1 1 1 1 2 2 2 0 Picornavirus 2B protein XPG_N PF00752.17 KXT03758.1 - 1.5e-24 86.4 0.0 3.7e-24 85.1 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KXT03758.1 - 1.1e-22 80.2 0.1 2.4e-22 79.1 0.1 1.6 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 KXT03758.1 - 1.2e-06 28.2 0.0 2.2e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.20 KXT03758.1 - 0.0025 18.4 0.0 0.0073 16.9 0.0 1.7 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold DUF5090 PF17009.5 KXT03759.1 - 8.3 6.3 6.5 14 5.6 6.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) Thioredoxin PF00085.20 KXT03760.1 - 1.3e-66 221.0 4.4 4.3e-33 113.4 0.2 4.4 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.6 KXT03760.1 - 1.4e-45 155.5 0.4 2.8e-32 112.1 0.0 3.6 3 1 1 4 4 4 3 Thioredoxin-like domain Calsequestrin PF01216.17 KXT03760.1 - 7.7e-11 41.6 0.5 2e-10 40.2 0.1 1.8 2 0 0 2 2 2 1 Calsequestrin Thioredoxin_7 PF13899.6 KXT03760.1 - 8.7e-11 41.9 0.9 0.0022 18.1 0.0 3.9 4 0 0 4 4 4 2 Thioredoxin-like Thioredoxin_8 PF13905.6 KXT03760.1 - 2.2e-09 37.5 0.0 0.027 14.8 0.0 4.5 4 1 1 5 5 5 2 Thioredoxin-like Thioredoxin_2 PF13098.6 KXT03760.1 - 1.2e-08 35.3 0.2 0.0014 19.0 0.1 3.0 2 0 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KXT03760.1 - 3.3e-07 29.9 0.3 0.00047 19.6 0.1 2.6 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 KXT03760.1 - 2.7e-06 27.3 1.2 0.073 13.0 0.1 3.1 3 0 0 3 3 3 2 AhpC/TSA family Redoxin PF08534.10 KXT03760.1 - 3.1e-05 23.7 3.0 0.098 12.4 0.0 3.4 3 0 0 3 3 3 2 Redoxin Thioredoxin_3 PF13192.6 KXT03760.1 - 0.014 15.5 0.4 0.16 12.0 0.1 2.8 2 0 0 2 2 2 0 Thioredoxin domain Sugar_tr PF00083.24 KXT03761.1 - 1.9e-75 254.4 22.6 2.3e-75 254.2 22.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXT03761.1 - 6.8e-08 31.8 42.8 1.6e-07 30.6 14.5 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KXT03761.1 - 0.00014 20.9 3.0 0.00014 20.9 3.0 2.2 2 0 0 2 2 2 2 MFS_1 like family MFS_2 PF13347.6 KXT03761.1 - 0.0011 17.6 17.8 0.0026 16.4 4.8 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein PH PF00169.29 KXT03762.1 - 7e-06 26.5 0.1 1.3e-05 25.7 0.1 1.5 1 0 0 1 1 1 1 PH domain Spc7 PF08317.11 KXT03762.1 - 0.022 13.7 1.5 0.038 12.9 1.5 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein ApoO PF09769.9 KXT03762.1 - 0.065 13.2 0.4 1.5 8.8 0.0 2.4 2 0 0 2 2 2 0 Apolipoprotein O OmpH PF03938.14 KXT03762.1 - 0.17 12.2 1.5 1.4 9.3 0.4 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Prominin PF05478.11 KXT03762.1 - 0.18 9.7 0.6 0.26 9.2 0.6 1.2 1 0 0 1 1 1 0 Prominin DUF334 PF03904.13 KXT03762.1 - 0.36 10.3 4.4 1.1 8.7 1.7 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF334) CRAL_TRIO PF00650.20 KXT03763.1 - 1.1e-43 148.7 0.0 1.7e-43 148.1 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KXT03763.1 - 1e-12 48.0 0.3 2.8e-12 46.6 0.3 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KXT03763.1 - 1e-06 29.0 0.0 1.9e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Ribonuclease_T2 PF00445.18 KXT03765.1 - 3.4e-41 141.5 0.7 6.4e-41 140.6 0.1 1.7 2 0 0 2 2 2 1 Ribonuclease T2 family UDG PF03167.19 KXT03766.1 - 7.3e-23 81.3 0.1 1.5e-22 80.2 0.1 1.5 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Tma16 PF11176.8 KXT03767.1 - 1.3e-49 167.9 2.8 1.6e-49 167.6 2.8 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 MmgE_PrpD PF03972.14 KXT03767.1 - 0.021 13.4 0.0 0.028 13.0 0.0 1.1 1 0 0 1 1 1 0 MmgE/PrpD family Methyltr_RsmF_N PF17125.5 KXT03767.1 - 0.049 14.1 0.8 0.24 11.9 0.2 2.0 1 1 1 2 2 2 0 N-terminal domain of 16S rRNA methyltransferase RsmF PPP4R2 PF09184.11 KXT03768.1 - 5 6.6 8.2 7.5 6.1 8.2 1.2 1 0 0 1 1 1 0 PPP4R2 BUD22 PF09073.10 KXT03768.1 - 5.8 6.2 10.8 7.9 5.7 10.8 1.1 1 0 0 1 1 1 0 BUD22 SGT1 PF07093.11 KXT03769.1 - 4e-87 293.0 16.4 2.6e-82 277.2 0.0 2.1 1 1 0 2 2 2 2 SGT1 protein SeleniumBinding PF11524.8 KXT03769.1 - 0.12 12.8 0.0 0.27 11.7 0.0 1.5 1 0 0 1 1 1 0 Selenium binding protein zf-AN1 PF01428.16 KXT03770.1 - 4.7e-12 45.9 5.4 4.7e-12 45.9 5.4 1.5 1 1 0 1 1 1 1 AN1-like Zinc finger ubiquitin PF00240.23 KXT03770.1 - 1.2e-11 44.2 0.0 2e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Transp_Tc5_C PF04236.15 KXT03770.1 - 0.0024 18.2 2.2 0.0041 17.4 2.2 1.4 1 0 0 1 1 1 1 Tc5 transposase C-terminal domain Sde2_N_Ubi PF13019.6 KXT03770.1 - 0.0081 16.0 0.2 0.0081 16.0 0.2 1.6 2 0 0 2 2 2 1 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 KXT03770.1 - 0.017 15.2 0.0 0.23 11.5 0.0 2.2 1 1 1 2 2 2 0 Ubiquitin-like domain Rad60-SLD PF11976.8 KXT03770.1 - 0.032 14.1 0.0 0.05 13.4 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KXT03770.1 - 0.11 13.0 0.1 0.17 12.5 0.1 1.5 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain ADH_zinc_N PF00107.26 KXT03772.1 - 6.3e-09 35.9 0.0 1.5e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXT03772.1 - 2.6e-06 27.3 0.1 1.1e-05 25.3 0.1 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain CDP-OH_P_transf PF01066.21 KXT03773.1 - 1.6e-13 51.2 0.6 3e-13 50.3 0.1 1.8 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Oxysterol_BP PF01237.18 KXT03774.1 - 4.9e-57 193.5 2.0 4.2e-55 187.1 2.0 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein Mab-21 PF03281.14 KXT03774.1 - 0.09 12.0 0.2 0.13 11.5 0.2 1.2 1 0 0 1 1 1 0 Mab-21 protein Cas9-BH PF16593.5 KXT03775.1 - 0.049 13.4 0.0 11 5.8 0.0 2.5 2 0 0 2 2 2 0 Bridge helix of CRISPR-associated endonuclease Cas9 Aldo_ket_red PF00248.21 KXT03776.1 - 3.5e-64 216.8 0.0 6.2e-64 216.0 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_17 PF00332.18 KXT03776.1 - 1.4e-05 24.9 0.5 1.4e-05 24.9 0.5 2.2 2 1 1 3 3 3 1 Glycosyl hydrolases family 17 DEC-1_N PF04625.13 KXT03776.1 - 0.018 14.1 8.5 0.044 12.8 8.5 1.7 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region CAP_N PF01213.19 KXT03776.1 - 5.7 6.3 16.7 2.9 7.3 13.9 1.9 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal WW PF00397.26 KXT03777.1 - 0.0044 17.1 0.5 0.0044 17.1 0.5 2.5 3 0 0 3 3 3 1 WW domain NAM-associated PF14303.6 KXT03777.1 - 0.0094 16.7 4.7 0.0094 16.7 4.7 2.0 2 0 0 2 2 2 1 No apical meristem-associated C-terminal domain CDC45 PF02724.14 KXT03777.1 - 4.1 5.6 8.1 5.2 5.2 8.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.7 KXT03777.1 - 4.8 5.2 4.6 6.4 4.8 4.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein zf-rbx1 PF12678.7 KXT03778.1 - 2.7e-08 34.0 0.6 6.1e-08 32.8 0.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KXT03778.1 - 4.8e-08 33.2 1.9 9.6e-08 32.2 1.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KXT03778.1 - 4.6e-05 23.3 0.5 8.6e-05 22.4 0.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KXT03778.1 - 0.00015 21.6 1.0 0.00027 20.7 1.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXT03778.1 - 0.00017 21.4 0.3 0.00034 20.4 0.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXT03778.1 - 0.00024 20.9 2.0 0.00054 19.8 2.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KXT03778.1 - 0.00035 20.4 0.5 0.00065 19.5 0.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KXT03778.1 - 0.0013 18.3 0.7 0.0025 17.4 0.7 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 KXT03778.1 - 0.0064 16.5 0.3 0.0064 16.5 0.3 1.8 2 0 0 2 2 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KXT03778.1 - 0.0091 16.0 0.6 0.018 15.1 0.6 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KXT03778.1 - 0.068 13.0 0.8 0.14 12.0 0.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 KXT03778.1 - 0.12 12.7 0.7 0.22 11.8 0.7 1.4 1 0 0 1 1 1 0 RING-like domain Allexi_40kDa PF05549.11 KXT03778.1 - 0.42 10.1 1.9 0.65 9.5 0.6 2.0 2 0 0 2 2 2 0 Allexivirus 40kDa protein ADH_N_assoc PF13823.6 KXT03778.1 - 1.6 8.7 3.5 5.2 7.1 3.5 1.9 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated zf-P11 PF03854.14 KXT03778.1 - 2.1 8.1 5.0 0.56 9.9 1.8 1.6 2 0 0 2 2 2 0 P-11 zinc finger CFEM PF05730.11 KXT03780.1 - 2.9e-05 24.1 1.7 3.8e-05 23.7 1.7 1.2 1 0 0 1 1 1 1 CFEM domain DnaJ PF00226.31 KXT03782.1 - 1.1e-20 73.5 1.1 1.1e-20 73.5 1.1 2.8 4 0 0 4 4 3 1 DnaJ domain TPR_1 PF00515.28 KXT03782.1 - 6.6e-13 47.9 13.4 0.0059 16.4 0.0 8.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.6 KXT03782.1 - 1.1e-12 47.9 0.0 0.02 15.1 0.0 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 KXT03782.1 - 1.4e-10 41.5 5.9 2.7e-05 24.6 1.0 5.7 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXT03782.1 - 6.3e-09 35.3 19.9 0.023 14.8 0.0 8.6 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_11 PF13414.6 KXT03782.1 - 1.3e-07 31.2 5.2 0.056 13.1 0.1 6.1 6 1 1 7 7 7 2 TPR repeat TPR_14 PF13428.6 KXT03782.1 - 1.5e-07 31.7 3.5 4.2 8.4 0.0 7.3 4 3 4 8 8 8 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXT03782.1 - 9.4e-06 25.5 10.6 0.48 10.8 0.0 7.3 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 KXT03782.1 - 3.6e-05 24.3 6.2 0.53 11.0 0.6 5.6 4 3 3 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 KXT03782.1 - 7.9e-05 22.8 11.4 0.023 15.1 0.1 5.6 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 KXT03782.1 - 0.00018 21.9 7.6 93 4.0 0.1 7.9 8 0 0 8 8 7 0 Tetratricopeptide repeat PknG_TPR PF16918.5 KXT03782.1 - 0.0025 16.6 0.1 0.052 12.3 0.0 2.5 3 0 0 3 3 3 1 Protein kinase G tetratricopeptide repeat ANAPC3 PF12895.7 KXT03782.1 - 0.0056 16.9 9.4 0.38 11.0 1.8 4.9 4 2 0 5 5 4 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF615 PF04751.14 KXT03782.1 - 0.027 14.5 2.6 0.065 13.2 2.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF615) DUF3562 PF12085.8 KXT03782.1 - 0.029 14.0 0.0 0.11 12.1 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3562) MLTD_N PF06474.12 KXT03782.1 - 0.087 13.0 0.1 0.43 10.8 0.1 2.2 2 0 0 2 2 2 0 MltD lipid attachment motif Thioredoxin_8 PF13905.6 KXT03782.1 - 0.29 11.5 1.7 0.37 11.2 0.1 2.0 2 0 0 2 2 2 0 Thioredoxin-like DUF1194 PF06707.11 KXT03782.1 - 0.31 10.2 4.1 2.1 7.5 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1194) TPR_12 PF13424.6 KXT03782.1 - 0.42 10.9 12.3 2.4 8.5 0.5 4.7 4 2 1 5 5 4 0 Tetratricopeptide repeat GlutR_dimer PF00745.20 KXT03782.1 - 0.87 10.1 10.0 0.57 10.7 3.0 3.1 3 1 0 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain zf-C2H2_jaz PF12171.8 KXT03783.1 - 5.6e-12 45.6 2.0 1.6e-11 44.2 2.0 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXT03783.1 - 1.7e-05 25.0 0.6 1.7e-05 25.0 0.6 1.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-U1 PF06220.12 KXT03783.1 - 0.003 17.3 0.8 0.005 16.6 0.2 1.7 2 0 0 2 2 2 1 U1 zinc finger zf-C2H2_4 PF13894.6 KXT03783.1 - 0.011 16.5 0.2 0.011 16.5 0.2 2.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KXT03783.1 - 0.095 13.0 1.8 0.18 12.2 1.8 1.5 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) ANAPC1 PF12859.7 KXT03784.1 - 1.9e-27 96.4 0.3 1.9e-27 96.4 0.3 3.2 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 1 Cullin PF00888.22 KXT03785.1 - 1.9e-15 56.6 0.0 3.2e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 KXT03785.1 - 0.00072 20.0 0.4 0.0022 18.5 0.0 2.1 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 DUF1827 PF08860.10 KXT03785.1 - 0.13 12.6 0.0 0.35 11.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1827) MFS_1 PF07690.16 KXT03787.1 - 1.1e-34 120.0 27.3 2.9e-33 115.3 26.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily LapA_dom PF06305.11 KXT03787.1 - 0.14 12.0 0.0 0.14 12.0 0.0 2.5 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Aa_trans PF01490.18 KXT03788.1 - 3.2e-43 148.0 41.3 3.9e-43 147.7 41.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 KXT03788.1 - 8e-05 21.6 39.3 8e-05 21.6 39.3 2.2 1 1 1 2 2 2 1 Amino acid permease TMEM125 PF15109.6 KXT03788.1 - 4 7.8 8.4 1.8 8.9 0.1 3.0 3 0 0 3 3 3 0 TMEM125 protein family BTB PF00651.31 KXT03789.1 - 4.3e-09 36.6 0.0 2.2e-08 34.3 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain LETM1 PF07766.13 KXT03789.1 - 0.13 11.5 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 LETM1-like protein Ribosomal_L29e PF01779.17 KXT03790.1 - 1.1e-20 73.6 11.3 1.7e-20 73.1 11.3 1.3 1 0 0 1 1 1 1 Ribosomal L29e protein family TRI12 PF06609.13 KXT03792.1 - 5e-42 144.1 24.8 6.3e-42 143.8 24.8 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KXT03792.1 - 1.8e-15 56.7 62.8 6.9e-15 54.8 59.5 3.4 2 1 1 3 3 3 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXT03792.1 - 8.7e-10 38.0 11.5 8.7e-10 38.0 11.5 3.8 4 1 0 4 4 4 1 Sugar (and other) transporter SpoIIIAC PF06686.11 KXT03792.1 - 0.62 10.3 0.1 0.62 10.3 0.1 4.7 5 1 1 6 6 6 0 Stage III sporulation protein AC/AD protein family MTS PF05175.14 KXT03793.1 - 0.014 14.9 0.0 0.032 13.8 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_23 PF13489.6 KXT03793.1 - 0.043 13.6 0.0 0.64 9.8 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain FAD_binding_3 PF01494.19 KXT03797.1 - 3e-44 151.7 0.0 3.6e-44 151.4 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXT03797.1 - 0.00021 21.4 0.0 0.00046 20.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXT03797.1 - 0.0079 15.5 0.2 0.043 13.1 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KXT03797.1 - 0.013 15.1 0.0 0.25 10.9 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KXT03797.1 - 0.013 14.3 0.0 0.031 13.0 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_2 PF07992.14 KXT03797.1 - 0.024 13.9 0.0 0.11 11.8 0.0 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXT03797.1 - 0.043 14.4 0.1 13 6.5 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXT03797.1 - 0.3 11.1 1.0 0.7 9.9 0.1 2.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding Cellulase PF00150.18 KXT03799.1 - 8e-10 38.6 0.0 1.4e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Pyridoxal_deC PF00282.19 KXT03799.1 - 0.021 13.5 0.1 0.032 13.0 0.1 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Glyco_hydro_43 PF04616.14 KXT03800.1 - 5e-30 104.8 0.8 6.5e-30 104.4 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 KXT03800.1 - 0.052 13.1 0.2 17 4.9 0.1 2.8 3 0 0 3 3 3 0 Glycosyl hydrolases family 32 N-terminal domain Aminotran_1_2 PF00155.21 KXT03801.1 - 1.2e-35 123.4 0.0 1.5e-35 123.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KXT03801.1 - 0.043 12.4 0.0 0.073 11.6 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DivIVA PF05103.13 KXT03802.1 - 0.0015 18.6 3.7 0.0016 18.5 3.7 1.1 1 0 0 1 1 1 1 DivIVA protein ISG65-75 PF11727.8 KXT03802.1 - 0.0088 15.3 8.1 0.011 15.0 8.1 1.0 1 0 0 1 1 1 1 Invariant surface glycoprotein DUF883 PF05957.13 KXT03802.1 - 0.16 12.6 5.5 0.22 12.1 5.5 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) MT0933_antitox PF14013.6 KXT03802.1 - 1 9.7 20.4 8.4 6.8 12.6 2.4 1 1 1 2 2 2 0 MT0933-like antitoxin protein Tannase PF07519.11 KXT03803.1 - 2.3e-93 313.7 0.0 3e-93 313.3 0.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase COesterase PF00135.28 KXT03803.1 - 9e-79 265.7 0.0 9.5e-74 249.1 0.0 2.1 1 1 1 2 2 2 2 Carboxylesterase family Peptidase_S9 PF00326.21 KXT03803.1 - 4.8e-07 29.5 0.1 0.0077 15.7 0.0 3.2 3 0 0 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KXT03803.1 - 7.5e-07 29.2 0.1 4.5e-06 26.7 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXT03803.1 - 0.00045 19.5 0.0 0.35 10.1 0.0 2.9 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXT03803.1 - 0.024 14.3 0.1 0.58 9.7 0.0 2.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold Esterase PF00756.20 KXT03803.1 - 0.05 13.2 0.0 5.4 6.6 0.0 2.3 2 0 0 2 2 2 0 Putative esterase Cyt-b5 PF00173.28 KXT03804.1 - 9.9e-10 38.4 0.0 1.8e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Msg2_C PF12373.8 KXT03804.1 - 0.06 12.8 1.7 3 7.3 0.0 2.4 2 0 0 2 2 2 0 Major surface glycoprotein 2 C terminal YtxH PF12732.7 KXT03804.1 - 4.6 7.8 10.9 1.5 9.4 3.9 2.5 2 0 0 2 2 2 0 YtxH-like protein UPF0506 PF11703.8 KXT03805.1 - 6.3 7.3 22.4 11 6.5 16.4 2.2 1 1 1 2 2 2 0 UPF0506 Conotoxin_I2 PF17557.2 KXT03805.1 - 6.4 7.0 18.7 8.3 6.6 2.8 2.4 2 0 0 2 2 2 0 I2-superfamily conotoxins Rsa3 PF14615.6 KXT03808.1 - 2.1e-21 75.2 0.2 2.8e-21 74.8 0.2 1.2 1 0 0 1 1 1 1 Ribosome-assembly protein 3 SR-25 PF10500.9 KXT03808.1 - 0.0027 17.4 9.4 0.0031 17.2 9.4 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF3283 PF11686.8 KXT03808.1 - 0.041 13.7 0.1 0.096 12.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3283) SPATA3 PF15662.5 KXT03808.1 - 0.23 12.1 9.2 0.25 12.0 9.2 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family EphA2_TM PF14575.6 KXT03808.1 - 0.98 10.3 4.3 1.8 9.5 4.3 1.5 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4100 PF13352.6 KXT03808.1 - 2.6 7.8 7.7 3.4 7.4 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4100) NPR3 PF03666.13 KXT03808.1 - 4.1 6.1 8.7 4.6 5.9 8.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 KXT03808.1 - 4.5 5.9 6.1 4.9 5.8 6.1 1.0 1 0 0 1 1 1 0 Presenilin ECH_1 PF00378.20 KXT03809.1 - 1.8e-45 155.3 0.0 4.8e-45 153.8 0.0 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXT03809.1 - 1.2e-24 87.5 0.0 1.4e-24 87.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Ytp1 PF10355.9 KXT03810.1 - 1.1e-107 359.4 9.6 1.1e-107 359.4 9.6 1.8 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KXT03810.1 - 1.9e-21 75.8 6.4 1.9e-21 75.8 6.4 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) EcsB PF05975.12 KXT03810.1 - 0.0052 15.7 3.1 1.6 7.5 2.6 2.4 2 0 0 2 2 2 2 Bacterial ABC transporter protein EcsB ICMT PF04140.14 KXT03810.1 - 0.019 15.4 0.1 0.058 13.8 0.1 1.8 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Clc-like PF07062.12 KXT03810.1 - 0.026 14.0 0.5 0.072 12.6 0.0 2.0 2 0 0 2 2 2 0 Clc-like CLP1_P PF16575.5 KXT03811.1 - 3.4e-35 121.6 0.0 5.3e-35 120.9 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop APH PF01636.23 KXT03812.1 - 2.7e-13 50.4 0.0 2.5e-12 47.3 0.0 2.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family PUF PF00806.19 KXT03813.1 - 1e-15 56.4 0.0 0.052 13.2 0.0 8.1 8 0 0 8 8 8 6 Pumilio-family RNA binding repeat DUF1722 PF08349.11 KXT03813.1 - 0.048 13.9 0.1 4.7 7.5 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1722) SPATA48 PF15073.6 KXT03814.1 - 0.018 15.3 0.5 0.02 15.2 0.5 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 48 Mob1_phocein PF03637.17 KXT03818.1 - 9.4e-70 234.0 0.0 1.5e-69 233.3 0.0 1.3 1 0 0 1 1 1 1 Mob1/phocein family SET PF00856.28 KXT03819.1 - 2.1e-10 41.3 0.1 4.5e-10 40.2 0.0 1.6 2 0 0 2 2 2 1 SET domain SprT-like PF10263.9 KXT03820.1 - 0.00063 19.6 0.3 0.24 11.2 0.0 2.7 2 0 0 2 2 2 2 SprT-like family Peptidase_M91 PF14891.6 KXT03820.1 - 0.19 12.0 0.1 5.5 7.3 0.0 2.2 2 0 0 2 2 2 0 Effector protein Peptidase_M43 PF05572.13 KXT03820.1 - 0.47 10.3 1.2 1.3 8.9 0.4 2.0 2 0 0 2 2 2 0 Pregnancy-associated plasma protein-A Peptidase_M24 PF00557.24 KXT03821.1 - 7.3e-49 166.3 0.0 9e-49 166.0 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 KXT03821.1 - 2.1e-19 69.6 8.9 4.4e-19 68.5 8.9 1.6 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KXT03821.1 - 0.0029 17.6 7.7 0.0029 17.6 7.7 2.2 2 0 0 2 2 2 1 MYND finger Urocanase PF01175.18 KXT03821.1 - 0.025 14.2 0.0 0.043 13.4 0.0 1.4 1 0 0 1 1 1 0 Urocanase Rossmann-like domain DUF520 PF04461.13 KXT03821.1 - 0.074 13.2 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF520) Metallophos PF00149.28 KXT03822.1 - 3.5e-40 138.7 0.1 4.6e-40 138.3 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KXT03822.1 - 5.5e-23 81.2 1.8 7.9e-23 80.6 1.1 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Dna2 PF08696.11 KXT03823.1 - 2.9e-65 219.9 0.4 5e-65 219.1 0.4 1.4 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.6 KXT03823.1 - 1.5e-49 168.3 0.0 2.6e-49 167.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KXT03823.1 - 7.6e-33 114.4 0.1 2.1e-17 63.8 0.0 2.6 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 KXT03823.1 - 2.4e-14 53.5 0.0 5.4e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXT03823.1 - 7.2e-12 45.9 0.2 1.5e-11 44.9 0.2 1.6 1 0 0 1 1 1 1 AAA domain Cas_Cas4 PF01930.17 KXT03823.1 - 2.4e-07 31.0 0.4 0.00027 21.1 0.0 3.4 3 0 0 3 3 3 1 Domain of unknown function DUF83 WH2 PF02205.20 KXT03823.1 - 3.3e-07 29.9 0.4 8.8e-07 28.6 0.4 1.8 1 0 0 1 1 1 1 WH2 motif UvrD-helicase PF00580.21 KXT03823.1 - 4.7e-05 23.1 0.1 9.7e-05 22.0 0.1 1.6 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 KXT03823.1 - 5.4e-05 23.1 0.0 0.00013 21.8 0.0 1.7 1 0 0 1 1 1 1 Helicase Viral_helicase1 PF01443.18 KXT03823.1 - 0.0011 18.7 1.2 2.4 7.8 0.0 3.4 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 KXT03823.1 - 0.0098 15.2 0.4 0.024 13.9 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 KXT03823.1 - 0.012 15.6 0.1 0.033 14.2 0.1 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Csa1 PF06023.12 KXT03823.1 - 0.014 14.8 0.1 0.087 12.2 0.1 2.1 1 1 0 1 1 1 0 CRISPR-associated exonuclease Csa1 SRP54 PF00448.22 KXT03823.1 - 0.016 14.8 0.1 0.029 14.0 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_7 PF12775.7 KXT03823.1 - 0.051 13.1 0.1 0.095 12.2 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 KXT03823.1 - 0.1 13.0 0.0 0.31 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain PhoH PF02562.16 KXT03823.1 - 0.11 11.9 0.1 0.47 9.9 0.1 2.0 1 1 0 1 1 1 0 PhoH-like protein Methyltransf_31 PF13847.6 KXT03824.1 - 7.3e-18 64.8 0.0 1.2e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXT03824.1 - 5.3e-07 29.6 0.0 8e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXT03824.1 - 2.2e-05 25.1 0.0 4.3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXT03824.1 - 2.7e-05 24.8 0.0 5.5e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXT03824.1 - 0.00067 20.3 0.0 0.0015 19.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KXT03824.1 - 0.002 18.1 0.0 0.0028 17.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KXT03824.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Xpo1 PF08389.12 KXT03825.1 - 6e-32 110.8 4.1 9.2e-32 110.2 0.1 3.4 4 1 0 4 4 4 1 Exportin 1-like protein MRP-S26 PF14943.6 KXT03826.1 - 0.0037 17.2 4.2 0.79 9.6 0.0 2.3 2 0 0 2 2 2 2 Mitochondrial ribosome subunit S26 UvrD_C PF13361.6 KXT03827.1 - 2.8e-60 204.6 1.9 6e-60 203.5 0.0 2.3 3 0 0 3 3 3 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 KXT03827.1 - 5.8e-56 190.3 11.5 2.5e-28 99.5 1.6 3.3 3 1 1 4 4 4 2 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 KXT03827.1 - 1.7e-33 116.0 0.5 4.3e-31 108.2 0.0 2.7 3 0 0 3 3 3 2 AAA domain UvrD_C_2 PF13538.6 KXT03827.1 - 5.6e-14 51.7 0.0 1.7e-13 50.2 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 KXT03827.1 - 6.5e-08 32.5 1.8 2.3e-05 24.2 0.1 2.7 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 KXT03827.1 - 8.1e-05 22.5 0.2 0.24 11.1 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 KXT03827.1 - 0.0078 16.0 5.4 0.011 15.5 0.0 3.1 3 0 0 3 3 3 1 AAA domain Helicase_RecD PF05127.14 KXT03827.1 - 0.17 11.7 1.0 0.83 9.5 0.0 2.4 2 0 0 2 2 2 0 Helicase MFS_1 PF07690.16 KXT03828.1 - 1e-53 182.5 74.4 1.6e-50 172.0 54.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXT03828.1 - 3.6e-26 91.8 25.9 5.5e-26 91.1 25.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KXT03828.1 - 2.8e-12 46.2 28.1 8.4e-12 44.7 13.0 2.8 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_4 PF06779.14 KXT03828.1 - 1.9e-07 30.7 25.6 2.7e-06 26.9 12.3 3.3 3 0 0 3 3 3 2 Uncharacterised MFS-type transporter YbfB DHHC PF01529.20 KXT03828.1 - 0.89 9.7 0.0 0.89 9.7 0.0 3.2 3 1 0 3 3 3 0 DHHC palmitoyltransferase SieB PF14163.6 KXT03828.1 - 1.9 8.0 5.3 5.1 6.6 0.1 2.7 2 0 0 2 2 2 0 Super-infection exclusion protein B zf-C2H2 PF00096.26 KXT03829.1 - 7.4e-09 35.6 12.4 0.00014 22.1 1.8 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXT03829.1 - 0.00011 22.7 11.2 0.037 14.9 1.4 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXT03829.1 - 0.0002 21.6 15.3 0.00027 21.2 2.4 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.7 KXT03829.1 - 0.014 15.7 3.0 0.035 14.5 1.1 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KXT03829.1 - 0.086 13.2 0.3 0.086 13.2 0.3 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Zn_ribbon_SprT PF17283.2 KXT03829.1 - 0.12 12.3 5.4 0.098 12.6 1.2 2.3 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf-C2H2_6 PF13912.6 KXT03829.1 - 0.66 10.0 4.0 0.17 11.9 0.6 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KXT03829.1 - 0.87 9.8 3.2 8.7 6.6 1.2 2.3 1 1 2 3 3 3 0 Zinc ribbon domain zf-C2HC_2 PF13913.6 KXT03829.1 - 5.2 7.1 6.0 0.31 11.0 0.4 1.9 2 0 0 2 2 2 0 zinc-finger of a C2HC-type ARPC4 PF05856.12 KXT03830.1 - 7.1e-78 260.0 2.7 8.7e-78 259.7 2.7 1.1 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) ARPC4 PF05856.12 KXT03831.1 - 2.3e-78 261.6 2.6 2.6e-78 261.4 2.6 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) DUF3602 PF12223.8 KXT03833.1 - 3.4e-13 50.0 22.3 3.2e-08 34.1 2.2 3.0 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) GTP1_OBG PF01018.22 KXT03833.1 - 0.057 13.0 5.2 5.7 6.5 0.3 3.0 1 1 2 3 3 3 0 GTP1/OBG PNPase_C PF12111.8 KXT03833.1 - 2.2 7.8 8.5 8.3 5.9 0.3 3.3 3 0 0 3 3 3 0 Polyribonucleotide phosphorylase C terminal TauE PF01925.19 KXT03835.1 - 0.044 13.4 0.6 0.062 12.9 0.2 1.4 2 0 0 2 2 2 0 Sulfite exporter TauE/SafE DUF981 PF06168.11 KXT03835.1 - 0.05 13.5 0.3 0.12 12.3 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF981) PGPGW PF09656.10 KXT03835.1 - 0.11 12.1 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 Putative transmembrane protein (PGPGW) LRR_6 PF13516.6 KXT03836.1 - 3.6e-11 42.2 27.4 0.0082 16.1 0.2 12.0 13 0 0 13 13 13 4 Leucine Rich repeat F-box-like PF12937.7 KXT03836.1 - 1.8e-10 40.5 1.4 2.9e-10 39.9 0.2 2.1 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KXT03836.1 - 3.4e-09 36.8 13.8 0.12 12.8 0.0 7.1 4 2 5 9 9 9 6 Leucine Rich repeats (2 copies) DUF1699 PF08004.11 KXT03836.1 - 0.0036 17.0 0.8 0.6 9.8 0.0 3.7 3 1 1 4 4 4 1 Protein of unknown function (DUF1699) F-box PF00646.33 KXT03836.1 - 0.012 15.5 0.4 0.012 15.5 0.4 3.0 3 0 0 3 3 3 0 F-box domain CagZ PF09053.10 KXT03836.1 - 0.071 12.7 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 CagZ DUF3818 PF12825.7 KXT03840.1 - 7e-52 176.5 1.1 5.5e-29 101.2 0.1 2.2 1 1 1 2 2 2 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 KXT03840.1 - 5.3e-34 117.0 0.0 1.3e-33 115.8 0.0 1.7 1 0 0 1 1 1 1 PX-associated ProQ PF04352.13 KXT03840.1 - 0.0036 17.2 0.2 0.56 10.1 0.0 2.7 2 0 0 2 2 2 2 ProQ/FINO family DUF5304 PF17230.2 KXT03840.1 - 0.0048 17.1 0.4 0.012 15.9 0.4 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5304) Yippee-Mis18 PF03226.14 KXT03841.1 - 2.2e-17 63.2 1.9 2.5e-17 63.0 1.9 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF2039 PF10217.9 KXT03841.1 - 0.018 15.4 0.6 0.018 15.4 0.6 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) RIG-I_C-RD PF11648.8 KXT03841.1 - 0.076 13.3 2.1 0.11 12.7 2.1 1.3 1 0 0 1 1 1 0 C-terminal domain of RIG-I p450 PF00067.22 KXT03843.1 - 2.5e-64 217.7 0.0 3.4e-64 217.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KXT03844.1 - 2.5e-64 217.7 0.0 3.4e-64 217.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KXT03845.1 - 2.5e-64 217.7 0.0 3.4e-64 217.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_1 PF00561.20 KXT03846.1 - 5.7e-05 22.9 0.0 7.2e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXT03846.1 - 0.003 18.2 0.1 0.0034 18.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXT03846.1 - 0.022 14.0 0.0 0.022 14.0 0.0 1.1 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Esterase PF00756.20 KXT03846.1 - 0.039 13.6 0.0 0.041 13.5 0.0 1.1 1 0 0 1 1 1 0 Putative esterase DUF3141 PF11339.8 KXT03846.1 - 0.11 10.9 0.0 0.13 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) adh_short PF00106.25 KXT03848.1 - 1.6e-32 112.5 0.0 2.2e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT03848.1 - 6.8e-20 71.6 0.0 8.8e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT03848.1 - 3.5e-06 27.1 0.0 5e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KXT03848.1 - 0.0084 15.5 0.0 2.3 7.5 0.0 2.0 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 KXT03848.1 - 0.0099 15.8 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3HCDH_N PF02737.18 KXT03848.1 - 0.015 15.2 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PQ-loop PF04193.14 KXT03849.1 - 1.3e-22 79.3 7.3 1.5e-13 50.3 4.5 2.7 2 0 0 2 2 2 2 PQ loop repeat Hydrolase_6 PF13344.6 KXT03850.1 - 4.9e-29 100.4 0.0 1e-28 99.4 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXT03850.1 - 5.4e-14 52.0 0.0 1.6e-13 50.5 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 KXT03850.1 - 1.6e-09 38.4 0.3 0.0042 17.4 0.0 3.0 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KXT03850.1 - 9e-05 22.6 0.6 0.098 12.7 0.0 3.2 3 1 1 4 4 4 2 Haloacid dehalogenase-like hydrolase NUDIX PF00293.28 KXT03851.1 - 1.1e-15 57.8 0.9 1.3e-15 57.5 0.9 1.1 1 0 0 1 1 1 1 NUDIX domain PEP-utilisers_N PF05524.13 KXT03852.1 - 0.0022 18.2 3.2 0.0035 17.5 3.2 1.4 1 0 0 1 1 1 1 PEP-utilising enzyme, N-terminal PEPcase_2 PF14010.6 KXT03852.1 - 0.0069 14.9 0.3 0.0079 14.8 0.3 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase Pfg27 PF09216.10 KXT03852.1 - 0.052 13.4 0.0 0.068 13.0 0.0 1.1 1 0 0 1 1 1 0 Pfg27 FUSC-like PF12805.7 KXT03852.1 - 0.14 11.3 0.2 0.17 10.9 0.2 1.1 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS FUSC PF04632.12 KXT03852.1 - 1 7.8 3.6 1 7.8 3.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family WD40 PF00400.32 KXT03853.1 - 3.2e-23 81.6 19.7 1.1e-05 26.1 0.0 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXT03853.1 - 1.1e-11 44.8 5.8 6.7e-05 23.1 0.2 4.3 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain ELYS-bb PF16687.5 KXT03853.1 - 0.01 14.5 0.2 0.08 11.5 0.0 2.3 2 1 1 3 3 3 0 beta-propeller of ELYS nucleoporin Ge1_WD40 PF16529.5 KXT03853.1 - 0.029 13.4 0.0 0.062 12.3 0.0 1.5 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein LRR_8 PF13855.6 KXT03854.1 - 9.4e-11 41.3 10.2 3.1e-07 30.1 1.2 3.0 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KXT03854.1 - 3.3e-09 36.9 12.6 4.5e-05 23.7 2.5 3.8 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KXT03854.1 - 3.3e-05 23.6 13.8 3.6 7.9 0.0 5.6 4 1 1 5 5 5 3 Leucine Rich repeat LRR_9 PF14580.6 KXT03854.1 - 4.5e-05 23.0 0.6 0.00014 21.5 0.5 1.7 1 1 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 KXT03854.1 - 0.0017 18.6 9.6 23 6.0 0.8 5.7 5 0 0 5 5 5 2 Leucine Rich Repeat Cyt-b5 PF00173.28 KXT03855.1 - 1.6e-17 63.4 0.0 2.3e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Abhydrolase_4 PF08386.10 KXT03856.1 - 1.3e-18 67.0 0.0 2.4e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 KXT03856.1 - 1.3e-16 61.0 0.1 6.8e-07 29.2 0.0 3.0 3 0 0 3 3 3 2 alpha/beta hydrolase fold DUF951 PF06107.11 KXT03856.1 - 0.025 14.5 0.0 0.052 13.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF951) DUF21 PF01595.20 KXT03857.1 - 3.1e-32 111.7 0.1 5.4e-32 110.9 0.1 1.4 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KXT03857.1 - 4.3e-06 27.1 0.2 0.21 12.1 0.0 3.4 4 0 0 4 4 4 2 CBS domain Sugar_tr PF00083.24 KXT03859.1 - 2.2e-88 297.1 27.8 2.6e-88 296.9 27.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXT03859.1 - 2.3e-15 56.4 36.5 1.4e-12 47.2 11.9 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily LptF_LptG PF03739.14 KXT03859.1 - 4.2 6.1 8.3 1.9 7.3 3.0 2.6 2 1 1 3 3 3 0 Lipopolysaccharide export system permease LptF/LptG ATE_C PF04377.15 KXT03860.1 - 1.6e-48 164.7 1.3 3.4e-48 163.7 1.3 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 KXT03860.1 - 7.9e-26 90.3 2.0 2.1e-25 88.9 2.0 1.7 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.7 KXT03860.1 - 0.0073 16.5 1.6 0.0083 16.3 0.4 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain ATE_C PF04377.15 KXT03861.1 - 2.1e-48 164.4 1.3 4.3e-48 163.3 1.3 1.5 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 KXT03861.1 - 2.5e-25 88.7 2.0 2.5e-25 88.7 2.0 2.1 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.7 KXT03861.1 - 0.0044 17.2 0.5 0.011 15.8 0.5 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain KH_1 PF00013.29 KXT03862.1 - 1.4e-41 140.1 7.5 2.1e-17 62.7 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KXT03862.1 - 2.4e-10 40.1 12.0 0.0028 17.4 1.6 3.4 3 1 0 3 3 3 3 KH domain KH_4 PF13083.6 KXT03862.1 - 1.1e-07 31.6 6.8 0.04 13.8 0.3 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 KXT03862.1 - 8.4e-05 22.6 6.0 0.13 12.4 0.1 3.3 3 0 0 3 3 3 2 NusA-like KH domain Nucleoside_tran PF01733.18 KXT03863.1 - 0.014 14.8 0.1 2 7.7 0.0 2.1 2 0 0 2 2 2 0 Nucleoside transporter AA_permease_C PF13906.6 KXT03863.1 - 0.1 12.7 4.1 0.29 11.2 0.4 2.6 2 0 0 2 2 2 0 C-terminus of AA_permease Baculo_11_kDa PF06143.11 KXT03863.1 - 0.13 11.9 2.5 0.15 11.7 0.0 2.1 2 0 0 2 2 2 0 Baculovirus 11 kDa family FixQ PF05545.11 KXT03863.1 - 0.17 11.9 0.0 0.17 11.9 0.0 2.5 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ UPF0114 PF03350.16 KXT03863.1 - 1.1 9.5 6.1 1 9.6 3.8 1.9 2 0 0 2 2 2 0 Uncharacterized protein family, UPF0114 DUF2150 PF09920.9 KXT03865.1 - 0.083 12.9 0.1 0.13 12.2 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2150) Ank_2 PF12796.7 KXT03866.1 - 8.2e-49 164.1 6.7 7.1e-13 49.0 0.0 4.8 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXT03866.1 - 3.5e-37 126.3 3.8 4.9e-12 46.1 0.4 6.4 4 2 2 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 KXT03866.1 - 1.7e-31 107.2 4.8 0.0049 17.2 0.6 9.6 9 0 0 9 9 9 8 Ankyrin repeat Ank_3 PF13606.6 KXT03866.1 - 1.4e-29 98.8 5.1 0.00095 19.5 0.0 9.9 9 1 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 KXT03866.1 - 4.2e-29 100.2 7.7 7.8e-10 38.8 0.0 7.2 3 1 4 7 7 7 6 Ankyrin repeats (many copies) CorA PF01544.18 KXT03866.1 - 1.4e-14 54.1 0.0 4.2e-14 52.5 0.0 1.8 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF3698 PF12479.8 KXT03866.1 - 1 10.0 3.1 15 6.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3698) DUF913 PF06025.12 KXT03868.1 - 1.8e-118 395.7 0.0 1.8e-118 395.7 0.0 7.2 6 1 0 6 6 6 2 Domain of Unknown Function (DUF913) DUF908 PF06012.12 KXT03868.1 - 1.8e-101 340.1 3.3 1.8e-101 340.1 3.3 5.5 5 2 0 6 6 6 1 Domain of Unknown Function (DUF908) HECT PF00632.25 KXT03868.1 - 9.7e-96 320.9 0.3 1.9e-95 319.9 0.2 1.5 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) UBM PF14377.6 KXT03868.1 - 3.6e-23 80.2 28.9 1.1e-08 34.3 0.5 5.2 3 1 1 4 4 4 4 Ubiquitin binding region Glyco_hydro_3_C PF01915.22 KXT03869.1 - 4.2e-38 131.4 0.0 6.9e-38 130.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXT03869.1 - 1.9e-33 116.2 0.0 2.7e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXT03869.1 - 6.3e-07 29.4 0.0 1.4e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Mt_ATP-synt_D PF05873.12 KXT03870.1 - 8e-22 77.7 1.9 1.1e-21 77.4 1.9 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) DUF2408 PF10303.9 KXT03870.1 - 0.025 15.1 0.2 0.042 14.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) DUF148 PF02520.17 KXT03870.1 - 0.041 14.0 6.2 0.03 14.4 4.1 1.8 1 1 0 1 1 1 0 Domain of unknown function DUF148 BLOC1_2 PF10046.9 KXT03870.1 - 0.14 12.5 2.8 0.25 11.7 2.4 1.6 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 XhlA PF10779.9 KXT03870.1 - 1.7 8.9 4.0 3 8.1 2.5 2.1 1 1 1 2 2 2 0 Haemolysin XhlA Amidohydro_3 PF07969.11 KXT03871.1 - 9e-13 48.5 0.4 3.9e-06 26.6 0.0 3.4 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_1 PF01979.20 KXT03871.1 - 2e-11 43.8 0.1 9.4e-07 28.5 0.0 3.4 3 0 0 3 3 3 3 Amidohydrolase family Aminotran_1_2 PF00155.21 KXT03872.1 - 2.5e-67 227.6 0.0 2.9e-67 227.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KXT03872.1 - 0.0017 17.4 0.0 0.0041 16.1 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KXT03872.1 - 0.0034 16.7 0.0 0.0052 16.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KXT03872.1 - 0.0045 16.4 0.0 0.0075 15.6 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KXT03872.1 - 0.0062 15.1 0.0 0.011 14.4 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme NGP1NT PF08153.12 KXT03873.1 - 2.7e-49 166.7 1.7 4.8e-49 165.8 1.7 1.4 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 KXT03873.1 - 4e-16 59.1 0.0 7e-13 48.7 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase Arf PF00025.21 KXT03873.1 - 9e-05 22.0 0.0 0.036 13.5 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KXT03873.1 - 0.00036 20.5 0.0 0.00091 19.2 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 KXT03873.1 - 0.0006 19.4 0.1 0.002 17.7 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KXT03873.1 - 0.0016 18.5 0.8 0.64 10.1 0.0 3.9 3 1 1 4 4 4 1 Dynamin family GTP_EFTU PF00009.27 KXT03873.1 - 0.01 15.4 0.1 1.2 8.6 0.0 3.3 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain adh_short PF00106.25 KXT03875.1 - 5.8e-19 68.3 0.0 9.6e-19 67.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT03875.1 - 7.6e-13 48.6 0.1 9.2e-13 48.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT03875.1 - 1.3e-08 35.0 0.1 2.8e-08 33.9 0.0 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KXT03875.1 - 4.8e-07 29.5 0.0 6.8e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXT03875.1 - 6.2e-06 25.8 0.0 9.1e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KXT03875.1 - 0.0005 19.3 0.1 0.0023 17.1 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 KXT03875.1 - 0.00082 18.5 0.0 0.0014 17.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KXT03875.1 - 0.0048 16.1 0.0 0.0071 15.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NeuB PF03102.14 KXT03875.1 - 0.12 11.8 0.0 15 4.9 0.0 2.2 2 0 0 2 2 2 0 NeuB family Ribosomal_L14e PF01929.17 KXT03876.1 - 1.2e-28 99.4 0.4 2.1e-28 98.6 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 KXT03876.1 - 4.8e-05 23.2 0.1 9.9e-05 22.2 0.1 1.6 1 0 0 1 1 1 1 KOW motif FKBP_C PF00254.28 KXT03877.1 - 2.9e-32 110.8 0.1 3.7e-32 110.5 0.1 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Chal_sti_synt_N PF00195.19 KXT03878.1 - 1.4e-20 73.7 0.0 2.1e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Chal_sti_synt_C PF02797.15 KXT03878.1 - 2.9e-20 72.8 0.0 5.7e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain ACP_syn_III_C PF08541.10 KXT03878.1 - 5.3e-06 26.5 0.0 1.8e-05 24.8 0.0 1.9 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Smr PF01713.21 KXT03879.1 - 0.0011 19.3 0.2 0.0024 18.2 0.2 1.6 1 0 0 1 1 1 1 Smr domain F-box-like PF12937.7 KXT03879.1 - 0.037 13.9 0.0 0.11 12.4 0.0 1.9 1 0 0 1 1 1 0 F-box-like SAM_Exu PF18609.1 KXT03879.1 - 0.068 13.3 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 Exuperantia SAM-like domain Sugar_tr PF00083.24 KXT03881.1 - 1.3e-109 367.0 23.4 2.3e-109 366.2 23.4 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXT03881.1 - 1.5e-15 57.0 42.4 1.8e-14 53.5 28.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 KXT03882.1 - 3.6e-63 213.9 0.0 5.7e-63 213.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KXT03883.1 - 3.6e-63 213.9 0.0 5.7e-63 213.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF1687 PF07955.11 KXT03885.1 - 6.8e-31 107.4 0.0 9e-31 107.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) ArsC PF03960.15 KXT03885.1 - 0.00045 20.2 0.0 0.0017 18.3 0.0 1.8 2 0 0 2 2 2 1 ArsC family EF-hand_10 PF14788.6 KXT03885.1 - 0.13 12.2 0.7 0.7 9.8 0.7 2.2 1 1 0 1 1 1 0 EF hand DUF1687 PF07955.11 KXT03886.1 - 6.8e-31 107.4 0.0 9e-31 107.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) ArsC PF03960.15 KXT03886.1 - 0.00045 20.2 0.0 0.0017 18.3 0.0 1.8 2 0 0 2 2 2 1 ArsC family EF-hand_10 PF14788.6 KXT03886.1 - 0.13 12.2 0.7 0.7 9.8 0.7 2.2 1 1 0 1 1 1 0 EF hand DUF1687 PF07955.11 KXT03887.1 - 6.8e-31 107.4 0.0 9e-31 107.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) ArsC PF03960.15 KXT03887.1 - 0.00045 20.2 0.0 0.0017 18.3 0.0 1.8 2 0 0 2 2 2 1 ArsC family EF-hand_10 PF14788.6 KXT03887.1 - 0.13 12.2 0.7 0.7 9.8 0.7 2.2 1 1 0 1 1 1 0 EF hand Pkinase PF00069.25 KXT03888.1 - 6.1e-64 215.9 0.0 7.5e-64 215.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT03888.1 - 2.5e-34 118.7 0.0 3.5e-34 118.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXT03888.1 - 5.8e-07 29.1 0.0 9.3e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KXT03888.1 - 9e-05 21.4 0.0 0.00014 20.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXT03888.1 - 0.17 11.2 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4451 PF14616.6 KXT03889.1 - 3.3e-15 56.4 3.6 7.8e-15 55.2 3.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4451) APC_rep PF18797.1 KXT03890.1 - 0.012 16.5 0.0 0.034 15.1 0.0 1.7 1 0 0 1 1 1 0 Adenomatous polyposis coli (APC) repeat adh_short_C2 PF13561.6 KXT03897.1 - 3.6e-55 187.1 0.2 4.4e-55 186.8 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXT03897.1 - 1.2e-51 174.9 0.2 1.7e-51 174.5 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXT03897.1 - 2.2e-11 44.0 0.9 2.6e-11 43.8 0.2 1.4 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KXT03897.1 - 6.1e-06 25.9 0.1 7.9e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXT03897.1 - 0.019 14.4 0.1 0.031 13.7 0.1 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Glyco_transf_5 PF08323.11 KXT03897.1 - 0.019 14.6 0.0 0.48 10.1 0.0 2.4 2 1 1 3 3 3 0 Starch synthase catalytic domain THF_DHG_CYH_C PF02882.19 KXT03897.1 - 0.036 13.4 0.1 0.11 11.9 0.0 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain La PF05383.17 KXT03898.1 - 2.2e-17 62.8 0.9 3.9e-17 62.1 0.9 1.4 1 0 0 1 1 1 1 La domain La PF05383.17 KXT03900.1 - 2.2e-17 62.8 0.9 3.9e-17 62.1 0.9 1.4 1 0 0 1 1 1 1 La domain DNA_pol_A_exo1 PF01612.20 KXT03901.1 - 0.082 12.6 0.1 0.22 11.2 0.0 1.7 2 0 0 2 2 2 0 3'-5' exonuclease RNase_T PF00929.24 KXT03901.1 - 0.2 12.2 0.2 0.86 10.1 0.2 2.1 1 1 0 1 1 1 0 Exonuclease THF_DHG_CYH PF00763.23 KXT03902.1 - 6.3e-23 81.3 0.0 1e-22 80.6 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 KXT03902.1 - 1.8e-14 53.4 0.0 9.9e-10 38.0 0.0 2.7 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DEDD_Tnp_IS110 PF01548.17 KXT03902.1 - 0.19 11.6 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 Transposase SecY PF00344.20 KXT03903.1 - 1.2e-71 241.5 8.5 1.6e-71 241.1 8.5 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 KXT03903.1 - 1.1e-17 63.5 0.2 2.9e-17 62.2 0.2 1.8 1 0 0 1 1 1 1 Plug domain of Sec61p DUF1751 PF08551.10 KXT03904.1 - 8.6e-24 84.0 0.5 1.8e-23 82.9 0.5 1.6 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 KXT03904.1 - 0.0044 17.0 6.9 0.0088 16.1 6.9 1.4 1 0 0 1 1 1 1 Rhomboid family ADH_N PF08240.12 KXT03905.1 - 6.4e-29 100.0 0.1 1.4e-28 99.0 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXT03905.1 - 3.9e-19 68.9 0.7 8.7e-19 67.8 0.7 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXT03905.1 - 8.8e-09 35.1 0.6 6.6e-05 22.5 0.0 2.3 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KXT03905.1 - 0.0011 20.1 0.2 0.0036 18.3 0.1 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase LsmAD PF06741.13 KXT03905.1 - 0.0079 16.7 0.0 0.014 15.9 0.0 1.4 1 0 0 1 1 1 1 LsmAD domain AlaDh_PNT_C PF01262.21 KXT03905.1 - 0.02 14.2 1.0 0.035 13.4 1.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 KXT03905.1 - 0.023 14.2 2.3 0.053 13.1 2.3 1.7 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.14 KXT03905.1 - 0.097 11.4 2.4 0.14 10.8 2.4 1.2 1 0 0 1 1 1 0 HI0933-like protein AdoHcyase_NAD PF00670.21 KXT03905.1 - 0.097 12.7 1.0 0.29 11.2 0.3 2.0 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ThiF PF00899.21 KXT03905.1 - 0.15 11.4 0.5 0.3 10.4 0.5 1.4 1 0 0 1 1 1 0 ThiF family Shikimate_DH PF01488.20 KXT03905.1 - 0.17 11.9 0.7 1.6 8.8 0.3 2.3 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 KXT03905.1 - 0.19 10.8 1.4 0.26 10.3 1.4 1.2 1 0 0 1 1 1 0 FAD binding domain MMS19_N PF14500.6 KXT03906.1 - 2.3e-92 309.3 0.0 2e-86 289.8 0.0 4.0 3 1 0 4 4 4 3 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 KXT03906.1 - 1.2e-87 294.8 2.0 5.7e-85 286.0 0.2 2.4 2 0 0 2 2 2 2 RNAPII transcription regulator C-terminal SH3_1 PF00018.28 KXT03906.1 - 1.6e-37 126.9 5.8 2e-12 46.5 0.1 4.1 4 0 0 4 4 4 3 SH3 domain SHD1 PF03983.12 KXT03906.1 - 7.6e-34 115.4 0.0 1.4e-33 114.5 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_9 PF14604.6 KXT03906.1 - 9.5e-32 108.6 4.9 1.1e-11 44.4 0.3 3.7 3 0 0 3 3 3 3 Variant SH3 domain SH3_2 PF07653.17 KXT03906.1 - 5.2e-22 77.3 0.0 6.5e-07 28.9 0.0 4.4 4 0 0 4 4 4 3 Variant SH3 domain SH3_10 PF17902.1 KXT03906.1 - 4.7e-08 33.0 0.1 0.03 14.4 0.0 3.3 3 0 0 3 3 3 2 SH3 domain SH3_3 PF08239.11 KXT03906.1 - 0.036 14.3 2.7 0.53 10.6 0.2 3.0 3 0 0 3 3 3 0 Bacterial SH3 domain SAM_4 PF18017.1 KXT03906.1 - 0.19 11.7 0.0 0.53 10.3 0.0 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) HEAT_EZ PF13513.6 KXT03906.1 - 0.26 11.8 4.0 7.8 7.1 0.2 4.4 3 1 0 3 3 3 0 HEAT-like repeat CUE PF02845.16 KXT03907.1 - 7.9e-09 35.1 0.0 1.3e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 CUE domain zf-C3HC4_2 PF13923.6 KXT03908.1 - 0.49 10.3 7.2 1.1 9.2 7.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXT03908.1 - 4.2 7.3 12.6 1.7 8.6 9.0 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Sugar_tr PF00083.24 KXT03909.1 - 2.9e-71 240.7 23.3 6.1e-70 236.3 23.4 2.7 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 KXT03909.1 - 9.7e-18 64.2 45.1 7.9e-11 41.5 8.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEM40 PF15817.5 KXT03909.1 - 1.7 8.4 5.0 0.91 9.3 0.5 2.6 2 1 1 3 3 3 0 Transmembrane protein 40 family HhH-GPD PF00730.25 KXT03910.1 - 2.8e-19 69.6 0.0 7.9e-19 68.1 0.0 1.8 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KXT03910.1 - 6.3e-09 35.2 0.0 2.7e-08 33.3 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif BRCT_2 PF16589.5 KXT03911.1 - 0.00014 22.2 0.0 0.00052 20.4 0.0 2.0 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KXT03911.1 - 0.002 18.5 0.0 0.0048 17.2 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 KXT03911.1 - 0.0037 17.1 0.0 0.0071 16.2 0.0 1.5 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain AT_hook PF02178.19 KXT03911.1 - 0.065 13.1 36.7 0.18 11.8 3.5 4.8 4 0 0 4 4 4 0 AT hook motif Mito_carr PF00153.27 KXT03912.1 - 4.7e-42 141.8 3.5 5.3e-15 55.1 1.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KXT03912.1 - 0.021 14.0 0.8 0.17 11.0 0.1 2.2 2 0 0 2 2 2 0 Gammaproteobacterial serine protease Bromo_TP PF07524.13 KXT03913.1 - 7.1e-07 29.1 0.0 1.3e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated Cyt-b5 PF00173.28 KXT03914.1 - 1.7e-10 40.9 0.1 2e-10 40.6 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain GFO_IDH_MocA PF01408.22 KXT03915.1 - 5.9e-22 78.7 0.0 9.1e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KXT03915.1 - 2.9e-07 30.5 0.0 5.4e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain TruB_C PF09142.11 KXT03915.1 - 0.0012 18.6 0.1 0.12 12.2 0.0 2.6 2 0 0 2 2 2 1 tRNA Pseudouridine synthase II, C terminal Isochorismatase PF00857.20 KXT03915.1 - 0.003 17.8 0.0 0.006 16.8 0.0 1.4 1 0 0 1 1 1 1 Isochorismatase family Methyltransf_5 PF01795.19 KXT03915.1 - 0.0086 15.6 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 MraW methylase family Pkinase PF00069.25 KXT03917.1 - 8.9e-60 202.3 0.0 6.7e-59 199.4 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT03917.1 - 1.5e-27 96.5 0.0 2.2e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXT03917.1 - 0.12 12.3 0.1 0.35 10.8 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family LCE6A PF15858.5 KXT03917.1 - 0.58 10.9 1.8 1.4 9.7 1.8 1.6 1 0 0 1 1 1 0 Late cornified envelope protein 6A family DEAD PF00270.29 KXT03918.1 - 4.3e-31 108.0 0.3 8e-31 107.1 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXT03918.1 - 8.2e-25 87.3 0.1 4.7e-24 84.9 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXT03918.1 - 2.7e-05 24.3 0.0 4.7e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KXT03918.1 - 0.00062 19.5 0.1 0.0019 17.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain tRNA-synt_1b PF00579.25 KXT03918.1 - 0.038 13.3 0.0 0.068 12.5 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) Flavi_DEAD PF07652.14 KXT03918.1 - 0.11 12.5 0.1 0.23 11.4 0.1 1.5 1 1 0 1 1 1 0 Flavivirus DEAD domain Glyco_hydro_18 PF00704.28 KXT03919.1 - 2.4e-24 86.6 0.0 2.7e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Amidohydro_2 PF04909.14 KXT03920.1 - 8.3e-22 78.3 0.0 1.1e-21 77.9 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Trans_coact PF16805.5 KXT03920.1 - 0.13 12.4 0.1 0.26 11.4 0.1 1.4 1 0 0 1 1 1 0 Phage late-transcription coactivator Snf7 PF03357.21 KXT03921.1 - 9.2e-35 119.8 12.7 1.2e-34 119.4 12.7 1.2 1 0 0 1 1 1 1 Snf7 ANAPC4_WD40 PF12894.7 KXT03922.1 - 9e-08 32.3 0.0 0.0012 19.1 0.0 5.2 3 2 2 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 KXT03922.1 - 3.4e-05 23.6 0.0 6.2e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 LisH PD40 PF07676.12 KXT03922.1 - 3.6e-05 23.6 1.8 0.5 10.4 0.1 4.2 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat WD40 PF00400.32 KXT03922.1 - 0.00011 22.9 9.5 1.5 9.9 0.1 6.0 7 0 0 7 7 7 2 WD domain, G-beta repeat Abhydrolase_3 PF07859.13 KXT03923.1 - 7.3e-30 104.4 0.0 1.1e-29 103.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXT03923.1 - 1.2e-19 70.4 0.0 3.4e-19 69.0 0.0 1.7 1 1 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KXT03923.1 - 0.0084 15.6 0.0 0.4 10.1 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family PAF-AH_p_II PF03403.13 KXT03924.1 - 1.6e-52 178.3 0.0 4.6e-26 91.2 0.0 3.1 3 0 0 3 3 3 3 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KXT03924.1 - 2.6e-07 29.8 0.0 6.7e-06 25.2 0.0 2.2 2 0 0 2 2 2 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KXT03924.1 - 0.00068 19.0 0.3 0.51 9.5 0.2 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 KXT03924.1 - 0.00097 18.2 0.5 0.0026 16.9 0.0 1.8 3 0 0 3 3 3 1 Chlorophyllase Methyltransf_2 PF00891.18 KXT03925.1 - 2.8e-19 69.3 0.0 4.9e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 KXT03925.1 - 0.0012 19.5 0.0 0.0039 17.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Mito_carr PF00153.27 KXT03926.1 - 9.2e-50 166.5 1.7 3e-16 59.1 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein FCH PF00611.23 KXT03927.1 - 2.8e-26 91.6 0.1 2.8e-26 91.6 0.1 2.6 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 KXT03927.1 - 1.6e-17 63.1 0.5 4.5e-08 32.8 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KXT03927.1 - 3.5e-17 61.8 0.0 2.2e-07 30.3 0.0 2.5 2 0 0 2 2 2 2 SH3 domain C1_1 PF00130.22 KXT03927.1 - 3e-13 49.4 4.9 5e-13 48.7 4.9 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_2 PF07653.17 KXT03927.1 - 0.00026 20.6 0.1 0.73 9.6 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain C1_2 PF03107.16 KXT03927.1 - 0.041 14.2 5.5 0.083 13.2 5.5 1.5 1 0 0 1 1 1 0 C1 domain SH3_10 PF17902.1 KXT03927.1 - 0.063 13.3 0.0 4.7 7.3 0.0 2.6 2 0 0 2 2 2 0 SH3 domain DUF3510 PF12022.8 KXT03927.1 - 0.58 10.5 5.6 0.21 12.0 0.8 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3510) PHD PF00628.29 KXT03927.1 - 0.85 9.6 5.9 1.8 8.5 5.9 1.5 1 0 0 1 1 1 0 PHD-finger CENP-S PF15630.6 KXT03928.1 - 1e-26 93.1 0.0 1.3e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KXT03928.1 - 2.2e-07 30.9 0.0 2.6e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 KXT03928.1 - 0.0027 17.7 0.0 0.0041 17.1 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated AAA PF00004.29 KXT03929.1 - 2.1e-91 303.2 0.0 2.4e-44 151.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXT03929.1 - 1.7e-15 56.6 0.1 8.2e-07 28.7 0.0 2.7 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 KXT03929.1 - 1.7e-12 47.4 0.0 2.3e-05 24.2 0.0 3.7 4 1 0 4 4 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KXT03929.1 - 5e-12 46.5 0.7 0.0022 18.4 0.0 4.6 3 2 1 4 4 3 2 AAA ATPase domain AAA_5 PF07728.14 KXT03929.1 - 1.1e-11 44.9 0.5 5.6e-06 26.4 0.1 3.6 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KXT03929.1 - 2.2e-10 40.9 0.0 0.0017 18.5 0.0 3.1 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KXT03929.1 - 4.1e-10 40.1 0.5 0.017 15.4 0.1 5.2 2 2 1 3 3 3 2 AAA domain AAA_33 PF13671.6 KXT03929.1 - 1.1e-09 38.6 0.0 0.00058 20.0 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.6 KXT03929.1 - 1.2e-08 34.7 1.7 0.023 14.3 0.0 5.1 4 1 1 5 5 5 2 AAA domain AAA_18 PF13238.6 KXT03929.1 - 9.5e-07 29.4 0.0 0.014 16.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 KXT03929.1 - 1.1e-06 28.8 0.0 0.037 14.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KXT03929.1 - 1.1e-06 28.1 0.3 0.11 11.8 0.0 3.5 4 0 0 4 4 4 2 Zeta toxin RNA_helicase PF00910.22 KXT03929.1 - 1.6e-06 28.5 0.0 0.038 14.4 0.0 2.9 2 2 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.21 KXT03929.1 - 1.7e-06 27.6 0.8 0.037 13.4 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KXT03929.1 - 2.3e-06 27.5 0.0 0.0023 17.8 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 KXT03929.1 - 2.5e-06 27.0 0.0 0.024 13.9 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain TsaE PF02367.17 KXT03929.1 - 3.5e-06 27.0 0.0 0.015 15.3 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 KXT03929.1 - 5.2e-06 26.8 0.0 0.0076 16.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 KXT03929.1 - 1.1e-05 25.5 0.0 0.036 14.0 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain NACHT PF05729.12 KXT03929.1 - 1.5e-05 25.0 0.4 0.052 13.5 0.0 3.5 4 0 0 4 4 4 1 NACHT domain IstB_IS21 PF01695.17 KXT03929.1 - 2.9e-05 23.9 0.0 0.24 11.1 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein Bac_DnaA PF00308.18 KXT03929.1 - 3.7e-05 23.7 0.0 0.1 12.4 0.0 3.6 2 2 0 2 2 2 1 Bacterial dnaA protein ABC_tran PF00005.27 KXT03929.1 - 4.1e-05 24.1 0.0 0.56 10.7 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_17 PF13207.6 KXT03929.1 - 6.9e-05 23.3 0.8 0.25 11.7 0.5 3.5 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KXT03929.1 - 0.00015 21.6 0.0 0.7 9.6 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 KXT03929.1 - 0.00019 21.8 0.0 0.1 12.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 KXT03929.1 - 0.00019 20.7 0.0 0.48 9.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Viral_helicase1 PF01443.18 KXT03929.1 - 0.0002 21.2 0.0 0.22 11.3 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 KXT03929.1 - 0.00029 20.8 0.0 0.56 10.1 0.0 3.1 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea AAA_11 PF13086.6 KXT03929.1 - 0.0003 20.7 0.0 0.21 11.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KXT03929.1 - 0.00037 20.0 0.1 1.3 8.5 0.1 3.2 2 1 0 2 2 2 1 P-loop containing dynein motor region AFG1_ATPase PF03969.16 KXT03929.1 - 0.0011 18.0 0.3 1.9 7.3 0.0 3.2 3 0 0 3 3 3 1 AFG1-like ATPase PhoH PF02562.16 KXT03929.1 - 0.0013 18.2 0.2 0.76 9.2 0.1 2.4 2 0 0 2 2 2 1 PhoH-like protein Sigma54_activat PF00158.26 KXT03929.1 - 0.0014 18.4 0.0 1.3 8.7 0.0 3.1 2 1 0 2 2 2 1 Sigma-54 interaction domain NB-ARC PF00931.22 KXT03929.1 - 0.0035 16.6 0.0 3.2 6.9 0.0 2.6 2 0 0 2 2 2 2 NB-ARC domain ATPase PF06745.13 KXT03929.1 - 0.011 15.1 0.2 4.7 6.5 0.0 3.1 3 0 0 3 3 3 0 KaiC TniB PF05621.11 KXT03929.1 - 0.016 14.6 0.0 5 6.5 0.0 2.9 3 0 0 3 3 3 0 Bacterial TniB protein SKI PF01202.22 KXT03929.1 - 0.028 14.5 0.0 4.1 7.5 0.0 2.7 2 0 0 2 2 2 0 Shikimate kinase PduV-EutP PF10662.9 KXT03929.1 - 0.049 13.4 0.0 3.9 7.2 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 KXT03929.1 - 0.055 13.4 0.1 13 5.6 0.0 2.9 2 1 1 3 3 3 0 NTPase SRPRB PF09439.10 KXT03929.1 - 0.068 12.6 0.0 48 3.3 0.0 3.6 4 0 0 4 4 3 0 Signal recognition particle receptor beta subunit AAA_30 PF13604.6 KXT03929.1 - 0.072 12.8 0.6 7.6 6.2 0.1 2.7 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 KXT03929.1 - 0.075 12.7 0.0 1.3 8.6 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_29 PF13555.6 KXT03929.1 - 0.11 12.3 0.0 6.5 6.6 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain Parvo_NS1 PF01057.17 KXT03929.1 - 0.12 11.5 0.1 10 5.1 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 MMR_HSR1 PF01926.23 KXT03929.1 - 0.19 11.8 0.1 57 3.8 0.0 4.0 3 1 1 4 4 4 0 50S ribosome-binding GTPase DnaB_C PF03796.15 KXT03929.1 - 0.82 9.0 4.5 2.8 7.2 0.4 3.2 3 1 1 4 4 4 0 DnaB-like helicase C terminal domain LtrA PF06772.11 KXT03931.1 - 2.5e-24 86.2 22.6 5.4e-23 81.8 17.3 2.1 2 0 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) Tmemb_14 PF03647.13 KXT03931.1 - 0.83 10.4 8.1 2.1 9.1 0.6 3.6 3 0 0 3 3 3 0 Transmembrane proteins 14C Utp12 PF04003.12 KXT03932.1 - 4.1e-22 78.5 0.4 6e-22 78.0 0.4 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family UTP15_C PF09384.10 KXT03932.1 - 0.072 12.8 0.5 0.11 12.1 0.5 1.3 1 0 0 1 1 1 0 UTP15 C terminal BUD22 PF09073.10 KXT03932.1 - 2.3 7.5 49.6 0.36 10.1 24.4 2.1 2 0 0 2 2 2 0 BUD22 Keratin_2_head PF16208.5 KXT03933.1 - 0.35 11.0 11.0 0.53 10.4 11.0 1.2 1 0 0 1 1 1 0 Keratin type II head DUF3176 PF11374.8 KXT03935.1 - 1.3e-31 109.0 2.3 4.5e-31 107.2 0.1 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) DUF2183 PF09949.9 KXT03936.1 - 1.1e-32 112.3 0.0 2.3e-32 111.3 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.13 KXT03936.1 - 0.0048 16.4 0.0 0.0079 15.7 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) CarboxypepD_reg PF13620.6 KXT03936.1 - 0.02 15.2 0.1 0.08 13.2 0.1 2.0 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain UIM PF02809.20 KXT03936.1 - 0.67 10.0 4.7 1.6 8.8 4.7 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif RFC1 PF08519.12 KXT03937.1 - 1.8e-58 197.1 0.3 5.3e-58 195.6 0.3 1.8 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 KXT03937.1 - 9e-13 48.4 0.0 3.3e-12 46.6 0.0 2.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 KXT03937.1 - 1.7e-09 38.2 0.1 4.2e-09 36.9 0.1 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KXT03937.1 - 1.2e-05 25.4 0.0 6.4e-05 23.0 0.0 2.1 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 KXT03937.1 - 0.00033 21.0 0.0 0.0011 19.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KXT03937.1 - 0.0012 19.0 0.1 0.0035 17.5 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXT03937.1 - 0.0026 18.2 0.1 0.02 15.3 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KXT03937.1 - 0.0078 16.0 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 KXT03937.1 - 0.016 15.2 0.0 0.045 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KXT03937.1 - 0.045 14.3 0.0 0.14 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KXT03937.1 - 0.14 12.1 0.0 0.97 9.3 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 KXT03937.1 - 0.33 11.2 0.0 0.33 11.2 0.0 1.8 2 0 0 2 2 1 0 AAA domain AT_hook PF02178.19 KXT03937.1 - 0.4 10.7 8.3 0.052 13.4 1.4 3.6 2 0 0 2 2 1 0 AT hook motif tRNA-synt_2d PF01409.20 KXT03938.1 - 3.7e-47 160.9 0.6 1.5e-24 86.8 0.0 2.4 2 1 1 3 3 3 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 KXT03938.1 - 5.9e-27 93.9 0.0 1.3e-26 92.8 0.0 1.6 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain BCDHK_Adom3 PF10436.9 KXT03939.1 - 4.9e-74 247.6 0.0 7.1e-74 247.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KXT03939.1 - 4.7e-13 49.6 0.0 1.1e-12 48.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1772 PF08592.11 KXT03940.1 - 0.00011 22.5 1.2 0.00015 22.1 1.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) F-box PF00646.33 KXT03941.1 - 2.8e-05 23.9 0.1 5.6e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXT03941.1 - 0.098 12.6 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 F-box-like TMF_TATA_bd PF12325.8 KXT03944.1 - 5.5e-33 113.6 10.3 5.5e-33 113.6 10.3 7.2 2 1 6 8 8 8 2 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 KXT03944.1 - 4.5e-18 65.0 19.5 4.5e-18 65.0 19.5 9.3 5 4 4 9 9 9 1 TATA element modulatory factor 1 DNA binding Matrilin_ccoil PF10393.9 KXT03944.1 - 8.5 6.3 11.7 52 3.8 0.1 4.9 4 0 0 4 4 4 0 Trimeric coiled-coil oligomerisation domain of matrilin HA2 PF04408.23 KXT03945.1 - 5.4e-18 65.2 0.1 1.5e-17 63.8 0.1 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KXT03945.1 - 7.9e-16 58.2 0.0 2e-15 56.9 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KXT03945.1 - 6e-12 45.9 0.0 1.3e-11 44.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 KXT03945.1 - 7.7e-05 23.1 0.2 0.00029 21.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KXT03945.1 - 0.00013 22.2 0.2 0.00063 20.0 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KXT03945.1 - 0.00039 20.2 0.1 0.00078 19.2 0.1 1.4 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 KXT03945.1 - 0.0057 16.5 1.2 0.045 13.5 1.2 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase cobW PF02492.19 KXT03945.1 - 0.019 14.6 0.1 0.35 10.4 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 KXT03945.1 - 0.048 12.7 0.0 0.12 11.4 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.6 KXT03945.1 - 0.083 12.9 0.0 4.5 7.3 0.0 2.5 1 1 1 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KXT03945.1 - 0.11 11.8 0.0 0.21 10.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin DUF2075 PF09848.9 KXT03945.1 - 0.16 11.2 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 KXT03945.1 - 0.19 11.2 0.0 1.4 8.4 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region ABC_tran PF00005.27 KXT03945.1 - 0.19 12.2 0.0 0.57 10.7 0.0 1.8 1 1 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 KXT03945.1 - 0.21 11.6 0.5 5.5 7.0 0.4 3.0 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Homeodomain PF00046.29 KXT03946.1 - 2.2e-14 53.0 4.4 1.6e-13 50.3 2.3 2.8 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 KXT03946.1 - 0.14 12.1 0.1 0.14 12.1 0.1 2.6 3 0 0 3 3 3 0 Homeobox KN domain Pkinase PF00069.25 KXT03947.1 - 1.4e-55 188.5 0.0 2e-55 188.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT03947.1 - 1.5e-31 109.6 0.0 9.8e-31 107.0 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KXT03947.1 - 0.02 13.9 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 KXT03947.1 - 0.035 13.1 0.0 0.052 12.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF1387 PF07139.11 KXT03947.1 - 1.8 8.2 0.0 1.8 8.2 0.0 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF1387) Ank_2 PF12796.7 KXT03948.1 - 8.4e-28 96.8 6.9 2.3e-11 44.1 0.1 4.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXT03948.1 - 1.8e-20 73.0 5.9 3.2e-06 27.6 0.0 5.3 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXT03948.1 - 1e-18 65.4 0.9 0.00015 21.9 0.0 6.6 8 0 0 8 8 6 3 Ankyrin repeat Ank_5 PF13857.6 KXT03948.1 - 1.6e-16 60.2 0.6 6.7e-05 23.1 0.1 4.7 1 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KXT03948.1 - 5.7e-16 58.2 5.1 6e-05 23.3 0.1 6.1 6 0 0 6 6 6 3 Ankyrin repeat Helo_like_N PF17111.5 KXT03948.1 - 0.00012 21.5 3.2 0.00023 20.6 3.2 1.5 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins sCache_like PF16736.5 KXT03948.1 - 0.01 16.0 1.1 1.4 9.0 0.1 3.3 3 0 0 3 3 3 1 Single Cache-like Symplekin_C PF12295.8 KXT03948.1 - 0.16 12.0 0.1 0.41 10.7 0.1 1.6 1 0 0 1 1 1 0 Symplekin tight junction protein C terminal DUF1843 PF08898.10 KXT03948.1 - 0.43 11.1 2.2 1.9 9.1 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) Seryl_tRNA_N PF02403.22 KXT03948.1 - 2.4 8.4 6.1 13 6.1 0.5 4.1 3 1 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain DUF4032 PF13224.6 KXT03948.1 - 2.8 7.8 5.8 0.77 9.6 0.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4032) Arginase PF00491.21 KXT03949.1 - 2.4e-82 276.6 0.2 3.1e-82 276.2 0.2 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KXT03949.1 - 0.14 12.3 0.3 0.22 11.8 0.3 1.2 1 0 0 1 1 1 0 UPF0489 domain Abhydrolase_1 PF00561.20 KXT03950.1 - 4.3e-09 36.4 0.0 1.6e-08 34.5 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXT03950.1 - 2.6e-06 28.2 5.8 2.5e-05 25.0 5.8 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family HKR_ArcB_TM PF18415.1 KXT03950.1 - 0.1 13.4 0.4 0.28 12.0 0.0 1.8 2 0 0 2 2 2 0 Histidine kinase receptor ArcB trans-membrane domain Mod_r PF07200.13 KXT03952.1 - 1.5e-27 96.5 9.1 1.9e-27 96.2 9.1 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Fez1 PF06818.15 KXT03952.1 - 0.11 12.9 7.4 0.19 12.2 7.4 1.3 1 0 0 1 1 1 0 Fez1 KxDL PF10241.9 KXT03952.1 - 2.8 8.3 8.1 1.7 9.0 5.2 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein Fe_bilin_red PF05996.12 KXT03952.1 - 3.2 7.4 6.1 0.2 11.3 0.8 1.7 2 0 0 2 2 2 0 Ferredoxin-dependent bilin reductase RRM_1 PF00076.22 KXT03954.1 - 5.2e-61 202.4 0.0 8e-18 64.0 0.0 5.4 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXT03954.1 - 2.8e-08 33.4 0.0 2e-05 24.2 0.0 2.4 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 KXT03954.1 - 3.5e-06 26.9 0.0 0.042 13.7 0.0 2.6 2 0 0 2 2 2 2 Rrp7 RRM-like N-terminal domain PHM7_cyt PF14703.6 KXT03954.1 - 0.00078 19.7 12.8 2.3 8.4 0.0 6.5 5 3 2 7 7 7 2 Cytosolic domain of 10TM putative phosphate transporter RRM_occluded PF16842.5 KXT03954.1 - 0.0029 17.4 0.0 0.33 10.9 0.0 2.7 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_7 PF16367.5 KXT03954.1 - 0.01 16.0 0.0 8 6.7 0.0 3.5 3 0 0 3 3 3 0 RNA recognition motif Mito_carr PF00153.27 KXT03955.1 - 2.8e-71 235.5 0.3 1.5e-25 88.9 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 KXT03955.1 - 7.6e-10 39.1 2.7 2.1e-05 24.9 0.1 3.8 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KXT03955.1 - 2.6e-09 36.2 0.6 3.5e-05 23.4 0.0 5.3 6 0 0 6 6 6 1 EF-hand domain EF-hand_1 PF00036.32 KXT03955.1 - 4.2e-07 29.1 2.2 1e-05 24.7 0.0 4.2 7 0 0 7 7 7 1 EF hand EF-hand_8 PF13833.6 KXT03955.1 - 3.8e-05 23.4 1.6 11 6.0 0.0 4.9 5 0 0 5 5 5 2 EF-hand domain pair EF-hand_5 PF13202.6 KXT03955.1 - 0.00032 20.1 0.2 0.0022 17.4 0.0 2.5 2 0 0 2 2 2 1 EF hand MurB_C PF02873.16 KXT03955.1 - 0.042 13.9 0.0 0.12 12.4 0.0 1.8 2 0 0 2 2 2 0 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain Serine_protease PF18405.1 KXT03955.1 - 0.23 10.6 0.2 16 4.5 0.0 2.9 3 1 1 4 4 4 0 Gammaproteobacterial serine protease Mito_carr PF00153.27 KXT03956.1 - 2.9e-71 235.5 0.3 1.6e-25 88.9 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 KXT03956.1 - 7.8e-10 39.1 2.7 2.1e-05 24.9 0.1 3.7 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KXT03956.1 - 2.8e-09 36.1 0.6 3.5e-05 23.4 0.0 5.3 6 0 0 6 6 6 1 EF-hand domain EF-hand_1 PF00036.32 KXT03956.1 - 4.4e-07 29.0 2.2 1e-05 24.7 0.0 4.2 7 0 0 7 7 7 1 EF hand EF-hand_8 PF13833.6 KXT03956.1 - 4e-05 23.4 1.6 11 5.9 0.0 4.9 5 0 0 5 5 5 2 EF-hand domain pair EF-hand_5 PF13202.6 KXT03956.1 - 0.00033 20.0 0.2 0.0022 17.4 0.0 2.5 2 0 0 2 2 2 1 EF hand MurB_C PF02873.16 KXT03956.1 - 0.042 13.9 0.0 0.12 12.4 0.0 1.8 2 0 0 2 2 2 0 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain Serine_protease PF18405.1 KXT03956.1 - 0.24 10.5 0.2 17 4.5 0.0 2.9 3 1 1 4 4 4 0 Gammaproteobacterial serine protease Methyltransf_4 PF02390.17 KXT03957.1 - 4.4e-51 172.8 0.0 6.9e-51 172.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.12 KXT03957.1 - 0.00036 21.2 0.1 0.0009 19.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXT03957.1 - 0.0023 18.6 0.0 0.0042 17.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KXT03957.1 - 0.0029 17.6 0.0 0.0052 16.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXT03957.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Orai-1 PF07856.12 KXT03957.1 - 1.3 8.7 5.9 0.12 12.1 0.3 2.1 2 0 0 2 2 2 0 Mediator of CRAC channel activity Fe_hyd_lg_C PF02906.14 KXT03958.1 - 2.4e-55 187.8 0.0 5.9e-55 186.6 0.0 1.7 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Pkinase PF00069.25 KXT03959.1 - 1.3e-59 201.8 0.0 6.1e-37 127.4 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXT03959.1 - 9.7e-28 97.1 0.0 2.7e-19 69.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 KXT03959.1 - 3e-13 49.9 0.1 6e-13 48.9 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 KXT03959.1 - 6.5e-07 29.0 0.0 2.9e-05 23.5 0.0 2.4 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KXT03959.1 - 3.2e-05 24.0 0.0 0.0011 18.9 0.1 2.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family PAS PF00989.25 KXT03959.1 - 0.0029 17.6 0.0 0.008 16.2 0.0 1.8 1 0 0 1 1 1 1 PAS fold Kdo PF06293.14 KXT03959.1 - 0.0032 16.8 0.0 0.0066 15.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KXT03959.1 - 0.019 13.9 0.0 0.019 13.9 0.0 1.8 2 0 0 2 2 1 0 Haspin like kinase domain PAS_9 PF13426.7 KXT03959.1 - 0.024 14.9 0.0 0.072 13.3 0.0 1.8 1 0 0 1 1 1 0 PAS domain PAS_4 PF08448.10 KXT03959.1 - 0.032 14.5 0.0 0.11 12.7 0.0 2.0 1 0 0 1 1 1 0 PAS fold Seadorna_VP7 PF07387.11 KXT03959.1 - 0.13 11.3 0.1 0.24 10.4 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 SelP_N PF04592.14 KXT03959.1 - 1.2 8.5 5.1 4.4 6.6 5.1 1.9 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Pkinase PF00069.25 KXT03960.1 - 1.2e-59 201.8 0.1 3.9e-41 141.2 0.3 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXT03960.1 - 1e-25 90.5 0.3 1.7e-20 73.4 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 KXT03960.1 - 1.3e-05 24.4 0.4 2.8e-05 23.2 0.1 1.6 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KXT03960.1 - 4.3e-05 23.5 0.2 0.046 13.6 0.2 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KXT03960.1 - 0.00015 21.2 0.1 0.00076 18.9 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXT03960.1 - 0.0035 16.7 0.7 0.021 14.2 0.0 2.3 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 KXT03960.1 - 0.011 15.4 2.3 1 9.0 0.1 2.9 2 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 KXT03960.1 - 0.028 14.0 0.9 0.047 13.3 0.0 1.7 2 0 0 2 2 2 0 RIO1 family SpoIIIAH PF12685.7 KXT03960.1 - 0.08 12.8 0.5 0.19 11.6 0.5 1.6 1 0 0 1 1 1 0 SpoIIIAH-like protein Seadorna_VP7 PF07387.11 KXT03960.1 - 0.2 10.7 0.0 0.3 10.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Asp PF00026.23 KXT03961.1 - 7.7e-06 25.5 0.1 1.6e-05 24.5 0.1 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease SKG6 PF08693.10 KXT03961.1 - 0.0014 18.0 1.1 0.0023 17.3 1.1 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Phage_HK97_TLTM PF06120.11 KXT03961.1 - 0.31 10.2 0.5 0.51 9.5 0.5 1.2 1 0 0 1 1 1 0 Tail length tape measure protein adh_short_C2 PF13561.6 KXT03962.1 - 9.1e-65 218.5 2.8 1e-64 218.3 2.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXT03962.1 - 5.1e-47 159.9 1.0 6.3e-47 159.6 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXT03962.1 - 1.7e-11 44.4 0.1 2.6e-11 43.8 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXT03962.1 - 5.9e-05 22.6 0.1 8.4e-05 22.1 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KXT03962.1 - 0.00091 18.4 0.1 0.0012 18.0 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF1776 PF08643.10 KXT03962.1 - 0.084 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) LPMO_10 PF03067.15 KXT03965.1 - 0.0038 17.9 0.2 0.023 15.4 0.2 2.3 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading DUF3602 PF12223.8 KXT03965.1 - 0.18 12.4 4.1 0.2 12.3 1.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3602) STE2 PF02116.15 KXT03967.1 - 2.2e-81 273.2 27.4 2.7e-81 273.0 27.4 1.1 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR PLA2_B PF01735.18 KXT03968.1 - 1.5e-18 66.5 0.2 3.9e-17 61.8 0.2 2.4 1 1 0 1 1 1 1 Lysophospholipase catalytic domain adh_short PF00106.25 KXT03969.1 - 1.4e-33 116.0 0.0 1.8e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT03969.1 - 2.8e-26 92.5 0.0 3.4e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KXT03969.1 - 5.1e-05 22.8 0.2 7.7e-05 22.3 0.2 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KXT03969.1 - 0.00024 21.1 0.1 0.0027 17.7 0.1 2.0 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 KXT03969.1 - 0.06 12.7 0.0 0.079 12.3 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) 3Beta_HSD PF01073.19 KXT03969.1 - 0.08 11.9 0.0 0.087 11.8 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KXT03969.1 - 0.14 12.0 0.1 0.16 11.9 0.1 1.3 1 1 0 1 1 1 0 NAD(P)H-binding SIR2 PF02146.17 KXT03970.1 - 1.6e-56 191.0 0.0 3e-56 190.1 0.0 1.5 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 KXT03970.1 - 9.5e-05 22.2 0.1 0.069 12.9 0.0 2.7 3 0 0 3 3 3 2 Thiamine pyrophosphate enzyme, central domain DUF592 PF04574.13 KXT03970.1 - 0.00045 20.0 0.0 0.00094 19.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF592) BES1_N PF05687.13 KXT03970.1 - 0.034 14.5 0.3 0.034 14.5 0.3 2.2 2 1 0 2 2 2 0 BES1/BZR1 plant transcription factor, N-terminal VWA_2 PF13519.6 KXT03971.1 - 2.7e-25 89.1 0.0 1.1e-24 87.2 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain Ssl1 PF04056.14 KXT03971.1 - 1.7e-09 37.8 0.0 2.3e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.28 KXT03971.1 - 8.8e-08 32.6 0.1 1.3e-07 32.0 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.20 KXT03971.1 - 0.048 13.6 0.3 0.11 12.5 0.3 1.6 1 0 0 1 1 1 0 Ubiquitin interaction motif DUF2405 PF10293.9 KXT03971.1 - 0.45 10.5 2.5 3.9 7.4 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2405) PI-PLC-X PF00388.19 KXT03972.1 - 2e-60 202.6 0.0 7.2e-60 200.8 0.0 2.0 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KXT03972.1 - 2.5e-41 140.6 0.2 5.5e-41 139.5 0.2 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.11 KXT03972.1 - 0.019 15.4 0.1 0.048 14.1 0.1 1.7 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like NCD2 PF04905.13 KXT03973.1 - 0.074 13.0 1.5 0.12 12.3 0.1 2.0 1 1 1 2 2 2 0 NAB conserved region 2 (NCD2) zf-C2H2_aberr PF17017.5 KXT03974.1 - 0.012 15.8 0.1 0.027 14.6 0.1 1.6 1 0 0 1 1 1 0 Aberrant zinc-finger zf-C2H2_4 PF13894.6 KXT03974.1 - 0.018 15.9 16.0 2.1 9.4 1.2 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KXT03974.1 - 0.049 14.1 17.6 0.14 12.6 2.4 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type KRAP_IP3R_bind PF14722.6 KXT03974.1 - 0.073 12.8 0.2 0.16 11.7 0.2 1.5 1 0 0 1 1 1 0 Ki-ras-induced actin-interacting protein-IP3R-interacting domain CENP-H PF05837.12 KXT03974.1 - 0.76 10.2 4.8 1.9 8.9 4.8 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DivIC PF04977.15 KXT03974.1 - 1.4 8.7 6.5 0.84 9.4 4.2 1.8 1 1 0 1 1 1 0 Septum formation initiator YabA PF06156.13 KXT03974.1 - 4.1 8.1 7.1 0.36 11.5 1.7 2.0 2 0 0 2 2 2 0 Initiation control protein YabA bZIP_2 PF07716.15 KXT03974.1 - 5.9 7.0 10.6 3.4 7.8 5.1 2.4 2 0 0 2 2 2 0 Basic region leucine zipper UQ_con PF00179.26 KXT03975.1 - 5.2e-32 110.4 0.0 1.1e-31 109.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXT03975.1 - 0.11 12.1 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic E2 family B DNA_RNApol_7kD PF03604.13 KXT03979.1 - 4e-17 61.6 6.4 5.2e-17 61.2 6.4 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.19 KXT03979.1 - 0.0039 17.2 0.1 0.0048 16.9 0.1 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 KXT03979.1 - 0.018 15.0 0.3 0.026 14.6 0.3 1.2 1 0 0 1 1 1 0 Double zinc ribbon zinc-ribbon_6 PF10005.9 KXT03979.1 - 0.031 15.0 0.2 0.04 14.6 0.2 1.2 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_13 PF09855.9 KXT03979.1 - 0.037 14.2 1.2 0.065 13.4 0.9 1.7 1 1 0 1 1 1 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) DUF2757 PF10955.8 KXT03979.1 - 0.069 13.4 0.2 0.085 13.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2757) A2L_zn_ribbon PF08792.10 KXT03979.1 - 0.17 11.7 2.7 0.28 10.9 2.7 1.3 1 0 0 1 1 1 0 A2L zinc ribbon domain AA_permease_2 PF13520.6 KXT03980.1 - 3.3e-40 138.2 37.2 7.7e-38 130.4 37.2 2.2 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXT03980.1 - 3.5e-15 55.6 33.8 4.1e-15 55.3 31.7 2.1 2 1 0 2 2 2 1 Amino acid permease DUF4674 PF15719.5 KXT03980.1 - 1.4 8.9 4.9 2.2 8.3 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4674) RNase_PH PF01138.21 KXT03981.1 - 5.2e-13 49.6 0.0 1.3e-12 48.4 0.0 1.7 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KXT03981.1 - 0.056 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 PilJ PF13675.6 KXT03981.1 - 0.089 12.8 0.1 0.85 9.7 0.0 2.2 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Lipase_GDSL_2 PF13472.6 KXT03984.1 - 5.1e-12 46.6 0.2 6.7e-12 46.2 0.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXT03984.1 - 0.0036 17.3 0.0 0.005 16.8 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PC4 PF02229.16 KXT03985.1 - 0.00087 18.9 0.0 0.0018 17.8 0.0 1.5 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) bZIP_1 PF00170.21 KXT03985.1 - 0.0056 16.7 18.4 0.19 11.8 3.0 4.4 2 1 2 4 4 4 3 bZIP transcription factor YejG PF13989.6 KXT03985.1 - 0.016 15.7 3.3 0.035 14.5 0.7 2.5 1 1 1 2 2 2 0 YejG-like protein Synaptonemal_3 PF15191.6 KXT03985.1 - 0.033 14.0 0.6 0.033 14.0 0.6 2.6 3 1 0 3 3 3 0 Synaptonemal complex central element protein 3 HMMR_N PF15905.5 KXT03985.1 - 0.19 11.2 38.5 0.97 8.8 1.9 2.2 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal GAS PF13851.6 KXT03985.1 - 2.1 7.6 41.2 2 7.7 9.3 3.6 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 KXT03985.1 - 2.9 8.0 59.4 2.6 8.1 10.8 4.9 2 2 2 4 4 4 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 KXT03985.1 - 3.9 6.3 48.2 1.8 7.4 11.4 3.0 1 1 2 3 3 3 0 Spc7 kinetochore protein ZYG-11_interact PF05884.12 KXT03985.1 - 7.6 5.8 6.0 2.6 7.4 2.7 1.8 1 1 0 2 2 2 0 Interactor of ZYG-11 APG6_N PF17675.1 KXT03985.1 - 8.3 7.0 56.6 0.8 10.2 15.8 3.7 1 1 2 3 3 3 0 Apg6 coiled-coil region PITH PF06201.13 KXT03986.1 - 2.6e-43 147.9 0.0 3.2e-43 147.6 0.0 1.1 1 0 0 1 1 1 1 PITH domain RNA_lig_T4_1 PF09511.10 KXT03986.1 - 0.1 12.4 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 RNA ligase tRNA-synt_1 PF00133.22 KXT03987.1 - 3.4e-40 137.9 0.0 9.7e-28 96.8 0.0 2.7 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KXT03987.1 - 3.3e-16 59.0 0.0 2.4e-09 36.4 0.0 3.0 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KXT03987.1 - 9.8e-11 41.8 0.0 2.1e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KXT03987.1 - 8.3e-07 28.6 0.0 4e-06 26.4 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1b PF00579.25 KXT03987.1 - 0.022 14.1 0.1 8.4 5.6 0.0 2.9 3 0 0 3 3 3 0 tRNA synthetases class I (W and Y) IMS PF00817.20 KXT03991.1 - 5.9e-37 127.0 0.0 1e-36 126.2 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KXT03991.1 - 5.7e-15 56.0 0.0 3.3e-14 53.6 0.1 2.0 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KXT03991.1 - 0.00064 19.9 0.0 0.0021 18.3 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif HHH_8 PF14716.6 KXT03991.1 - 0.11 12.9 0.0 0.51 10.8 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix domain Clat_adaptor_s PF01217.20 KXT03992.1 - 2.3e-44 150.8 0.0 3.4e-44 150.2 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TLV_coat PF00429.19 KXT03992.1 - 0.0052 15.5 4.0 0.0066 15.2 4.0 1.2 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) AICARFT_IMPCHas PF01808.18 KXT03992.1 - 0.082 12.3 0.4 0.12 11.8 0.4 1.2 1 0 0 1 1 1 0 AICARFT/IMPCHase bienzyme Aldo_ket_red PF00248.21 KXT03993.1 - 2.4e-44 151.7 0.0 3.7e-42 144.5 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family DUF4483 PF14825.6 KXT03993.1 - 0.19 11.5 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4483) MIOX PF05153.15 KXT03994.1 - 8.1e-123 408.8 1.3 1.4e-122 408.1 1.3 1.3 1 0 0 1 1 1 1 Myo-inositol oxygenase Cytochrom_C_2 PF01322.20 KXT03994.1 - 0.046 14.6 2.5 0.081 13.8 2.5 1.4 1 0 0 1 1 1 0 Cytochrome C' HD PF01966.22 KXT03994.1 - 0.15 12.3 0.3 0.77 10.0 0.0 2.2 3 0 0 3 3 3 0 HD domain Ribosomal_L16 PF00252.18 KXT03995.1 - 4.6e-31 107.6 0.0 6.7e-31 107.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DUF4050 PF13259.6 KXT03996.1 - 7.1e-50 169.9 0.8 7.1e-50 169.9 0.8 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4050) MRI PF15325.6 KXT03996.1 - 0.004 18.2 14.2 0.029 15.5 7.5 2.7 2 0 0 2 2 2 2 Modulator of retrovirus infection Polyoma_lg_T_C PF06431.11 KXT03996.1 - 0.22 10.4 1.3 0.36 9.6 1.3 1.2 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus NOA36 PF06524.12 KXT03996.1 - 1.1 8.5 5.5 1.9 7.7 5.5 1.4 1 0 0 1 1 1 0 NOA36 protein RRM_1 PF00076.22 KXT03997.1 - 5.8e-13 48.5 0.7 3.8e-06 26.6 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXT03997.1 - 8.8e-06 25.8 0.0 2.3e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif RRM_3 PF08777.11 KXT03997.1 - 0.029 14.4 9.9 0.072 13.1 4.0 2.9 3 0 0 3 3 3 0 RNA binding motif BRAP2 PF07576.12 KXT03997.1 - 0.14 12.4 0.0 0.39 11.0 0.0 1.7 2 0 0 2 2 2 0 BRCA1-associated protein 2 PhoD PF09423.10 KXT03999.1 - 2e-07 30.4 0.2 0.00037 19.6 0.0 2.8 2 1 0 2 2 2 2 PhoD-like phosphatase FMO-like PF00743.19 KXT04000.1 - 8.5e-09 34.4 0.0 1.5e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KXT04000.1 - 6.8e-06 25.5 0.0 6.8e-05 22.2 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KXT04000.1 - 0.00025 20.4 0.0 0.0017 17.7 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase LBR_tudor PF09465.10 KXT04000.1 - 0.017 14.9 0.1 0.041 13.7 0.1 1.6 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain GrpE PF01025.19 KXT04003.1 - 1.6e-40 138.5 9.7 2.4e-40 137.9 9.7 1.3 1 1 0 1 1 1 1 GrpE DUF1664 PF07889.12 KXT04003.1 - 0.57 10.2 5.2 13 5.8 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FliT PF05400.13 KXT04003.1 - 1.7 9.5 8.0 0.51 11.2 4.7 1.9 2 1 0 2 2 2 0 Flagellar protein FliT HSP70 PF00012.20 KXT04003.1 - 2.5 6.2 10.5 3.4 5.7 10.5 1.1 1 0 0 1 1 1 0 Hsp70 protein DUF4407 PF14362.6 KXT04003.1 - 2.6 7.3 6.4 3.6 6.9 6.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ALMT PF11744.8 KXT04003.1 - 3.6 6.3 5.7 4.9 5.9 5.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter APG6_N PF17675.1 KXT04003.1 - 9.9 6.7 16.7 11 6.6 15.3 1.7 1 1 1 2 2 2 0 Apg6 coiled-coil region p450 PF00067.22 KXT04004.1 - 1.7e-67 228.2 0.0 2.4e-67 227.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Bromodomain PF00439.25 KXT04006.1 - 1.4e-40 137.3 0.0 7.4e-19 67.6 0.1 3.1 3 0 0 3 3 3 2 Bromodomain BET PF17035.5 KXT04006.1 - 1.1e-12 47.9 0.5 2.2e-12 46.9 0.5 1.6 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation DUF3305 PF11749.8 KXT04006.1 - 0.14 12.3 1.6 0.87 9.7 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3305) RGS-like PF09128.11 KXT04006.1 - 0.17 11.6 0.5 1.1 8.9 0.0 2.4 2 0 0 2 2 2 0 Regulator of G protein signalling-like domain FlxA PF14282.6 KXT04006.1 - 0.46 10.5 13.5 0.77 9.8 0.5 3.7 2 1 1 3 3 3 0 FlxA-like protein FUSC PF04632.12 KXT04006.1 - 1 7.8 2.9 1.9 6.9 2.9 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3138 PF11336.8 KXT04006.1 - 1 7.9 7.4 1.9 7.0 7.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Glyco_hydro_72 PF03198.14 KXT04007.1 - 2.6e-133 444.2 2.9 3.1e-133 443.9 2.9 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 KXT04007.1 - 2.3e-05 24.0 0.1 0.0002 20.9 0.1 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 KXT04007.1 - 0.00012 21.3 0.1 0.00053 19.2 0.1 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Torus PF16131.5 KXT04008.1 - 0.021 15.5 4.8 0.7 10.6 1.4 2.4 2 0 0 2 2 2 0 Torus domain PHD PF00628.29 KXT04008.1 - 1.7 8.6 4.8 3 7.8 1.0 2.6 2 0 0 2 2 2 0 PHD-finger SH3_9 PF14604.6 KXT04009.1 - 1.5e-30 104.8 2.7 4.1e-15 55.4 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KXT04009.1 - 9.8e-30 101.9 5.1 3.9e-15 55.2 0.6 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 KXT04009.1 - 1.9e-17 62.7 0.0 1.2e-07 31.3 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.20 KXT04009.1 - 3.5e-16 59.1 0.0 6e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein FOG_N PF15888.5 KXT04009.1 - 0.087 13.2 0.2 4 7.8 0.1 2.6 2 0 0 2 2 2 0 Folded gastrulation N-terminus MFS_1 PF07690.16 KXT04010.1 - 8.3e-35 120.3 25.2 8.3e-35 120.3 25.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily GPI2 PF06432.11 KXT04010.1 - 3.7 6.9 13.0 0.38 10.2 0.6 2.6 2 1 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase Sugar_tr PF00083.24 KXT04011.1 - 1.4e-88 297.7 8.8 1.9e-88 297.4 8.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXT04011.1 - 9.2e-32 110.3 55.2 3.9e-27 95.1 31.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXT04011.1 - 2.4e-05 23.1 24.5 0.0019 16.8 0.7 3.7 3 1 1 4 4 4 3 MFS/sugar transport protein DUF1989 PF09347.10 KXT04012.1 - 7.2e-15 55.0 0.1 2.4e-14 53.3 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1989) CNOT1_HEAT PF16418.5 KXT04012.1 - 0.15 12.2 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 HEAT repeat F-box-like PF12937.7 KXT04013.1 - 1e-09 38.1 2.4 1.7e-08 34.3 0.2 2.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXT04013.1 - 0.0018 18.1 5.0 0.021 14.7 5.0 2.5 1 1 0 1 1 1 1 F-box domain Voltage_CLC PF00654.20 KXT04022.1 - 0.056 12.7 5.5 0.069 12.4 5.5 1.1 1 0 0 1 1 1 0 Voltage gated chloride channel DUF4229 PF14012.6 KXT04022.1 - 9.1 6.5 10.8 8.9 6.5 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4229) zf-DNL PF05180.12 KXT04023.1 - 7.8e-25 86.6 4.2 1.8e-24 85.4 4.2 1.7 1 0 0 1 1 1 1 DNL zinc finger zinc_ribbon_4 PF13717.6 KXT04023.1 - 0.013 15.4 1.1 0.13 12.2 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain RNHCP PF12647.7 KXT04023.1 - 0.098 12.6 2.5 1.5 8.8 3.2 2.2 1 1 1 2 2 2 0 RNHCP domain Asp-B-Hydro_N PF05279.11 KXT04023.1 - 1.8 8.6 13.9 2.5 8.1 13.9 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region V_ATPase_I PF01496.19 KXT04023.1 - 8.5 4.1 8.2 14 3.5 8.2 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pep_deformylase PF01327.21 KXT04024.1 - 0.21 11.2 0.0 0.34 10.5 0.0 1.3 1 0 0 1 1 1 0 Polypeptide deformylase PrpF PF04303.13 KXT04025.1 - 3e-89 299.6 0.3 3.7e-89 299.3 0.3 1.0 1 0 0 1 1 1 1 PrpF protein Glyco_hydro_cc PF11790.8 KXT04026.1 - 1.7e-56 191.5 1.4 2.3e-56 191.0 1.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Flocculin_t3 PF13928.6 KXT04026.1 - 3.9 8.1 10.1 19 5.9 1.3 3.1 2 0 0 2 2 2 0 Flocculin type 3 repeat DUF5407 PF17401.2 KXT04028.1 - 0.031 14.5 0.0 0.049 13.9 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5407) EMP70 PF02990.16 KXT04032.1 - 2.6e-205 683.0 5.6 3.5e-205 682.6 5.6 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 DUF1375 PF07119.12 KXT04032.1 - 0.098 13.1 0.1 0.3 11.5 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1375) Pyrid_ox_like PF16242.5 KXT04033.1 - 2.3e-27 95.4 0.0 3.7e-27 94.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 KXT04033.1 - 1.1e-09 38.4 0.0 2.1e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase JCAD PF15351.6 KXT04033.1 - 0.05 11.4 0.9 0.066 11.0 0.9 1.1 1 0 0 1 1 1 0 Junctional protein associated with coronary artery disease Gpr1_Fun34_YaaH PF01184.19 KXT04034.1 - 4.8e-35 121.1 26.0 6e-35 120.7 26.0 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DEAD PF00270.29 KXT04035.1 - 7.7e-48 162.6 0.0 6.1e-47 159.6 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXT04035.1 - 5.5e-33 113.6 0.1 2.6e-29 101.8 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 KXT04035.1 - 2.8e-07 30.7 2.9 3.9e-07 30.2 0.0 2.5 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KXT04035.1 - 0.0023 17.2 0.0 0.0023 17.2 0.0 2.6 3 0 0 3 3 3 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_RecD PF05127.14 KXT04035.1 - 0.029 14.2 0.0 0.029 14.2 0.0 2.6 3 0 0 3 3 3 0 Helicase MOZ_SAS PF01853.18 KXT04036.1 - 8.1e-67 224.4 0.0 1e-66 224.0 0.0 1.1 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KXT04036.1 - 1.2e-15 56.8 1.1 2.8e-15 55.7 1.1 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 KXT04036.1 - 0.043 14.2 0.0 0.094 13.2 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXT04036.1 - 0.13 12.5 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family IATP PF04568.12 KXT04037.1 - 7.6e-19 68.0 1.4 8e-19 67.9 1.4 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP DUF4407 PF14362.6 KXT04037.1 - 0.17 11.2 5.6 0.2 11.0 5.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) tRNA-synt_2 PF00152.20 KXT04038.1 - 6.7e-90 301.3 0.0 9.9e-90 300.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KXT04038.1 - 2.2e-11 43.6 0.0 3.7e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 KXT04038.1 - 0.15 12.3 0.0 0.38 11.0 0.0 1.6 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain YdfA_immunity PF12127.8 KXT04038.1 - 4.1 6.4 5.5 6.2 5.8 5.5 1.2 1 0 0 1 1 1 0 SigmaW regulon antibacterial Amino_oxidase PF01593.24 KXT04039.1 - 8.6e-60 203.3 0.1 5.4e-59 200.7 0.1 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KXT04039.1 - 1.2e-14 54.3 0.4 2.3e-14 53.4 0.4 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXT04039.1 - 6.7e-07 29.2 0.0 1.1e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXT04039.1 - 1.2e-06 29.0 0.3 1.1e-05 25.9 0.7 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXT04039.1 - 5e-06 26.0 0.2 9.1e-06 25.1 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXT04039.1 - 8.3e-05 21.8 1.3 0.00014 21.0 1.3 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 KXT04039.1 - 8.7e-05 21.9 1.9 0.00013 21.3 1.9 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KXT04039.1 - 0.00024 20.6 0.0 0.00032 20.2 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KXT04039.1 - 0.00032 20.0 0.4 0.0012 18.1 0.4 1.9 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.21 KXT04039.1 - 0.00052 19.4 0.5 0.001 18.4 0.5 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KXT04039.1 - 0.00056 18.7 0.3 0.00097 17.9 0.3 1.4 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 KXT04039.1 - 0.015 14.4 0.5 0.03 13.4 0.5 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A K_oxygenase PF13434.6 KXT04039.1 - 0.026 13.7 0.6 4.8 6.2 0.0 2.4 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Vitellogenin_N PF01347.22 KXT04039.1 - 0.063 11.7 0.0 0.092 11.1 0.0 1.1 1 0 0 1 1 1 0 Lipoprotein amino terminal region Pyr_redox_3 PF13738.6 KXT04039.1 - 0.091 12.0 0.1 0.14 11.3 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Cullin PF00888.22 KXT04040.1 - 3.4e-199 663.5 8.8 4.5e-199 663.1 8.8 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KXT04040.1 - 5.1e-25 87.3 1.0 1.6e-24 85.7 1.0 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain SNF5 PF04855.12 KXT04041.1 - 2.3e-61 207.6 2.1 6.4e-60 202.9 2.1 2.2 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 SNF5 PF04855.12 KXT04042.1 - 2.3e-61 207.6 2.1 6.4e-60 202.9 2.1 2.2 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 p450 PF00067.22 KXT04043.1 - 1.3e-60 205.5 0.0 1.6e-60 205.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 KXT04044.1 - 8.1e-41 140.1 0.0 9.1e-41 140.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT04044.1 - 5.8e-16 58.6 0.0 7.6e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXT04044.1 - 0.0002 20.8 0.0 0.00028 20.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXT04044.1 - 0.0007 19.6 0.1 0.53 10.2 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXT04044.1 - 0.0098 14.7 0.0 0.015 14.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXT04044.1 - 0.011 15.2 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KXT04044.1 - 0.021 14.3 0.0 0.061 12.8 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Pkinase PF00069.25 KXT04045.1 - 8.1e-41 140.1 0.0 9.1e-41 140.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT04045.1 - 5.8e-16 58.6 0.0 7.6e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXT04045.1 - 0.0002 20.8 0.0 0.00028 20.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KXT04045.1 - 0.0007 19.6 0.1 0.53 10.2 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXT04045.1 - 0.0098 14.7 0.0 0.015 14.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KXT04045.1 - 0.011 15.2 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KXT04045.1 - 0.021 14.3 0.0 0.061 12.8 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL PHD PF00628.29 KXT04046.1 - 5.5e-16 58.2 15.9 2e-09 37.2 5.4 2.7 2 1 1 3 3 3 2 PHD-finger zf-HC5HC2H PF13771.6 KXT04046.1 - 0.0014 18.8 4.9 0.025 14.8 0.7 2.5 2 0 0 2 2 2 2 PHD-like zinc-binding domain zf-PHD-like PF15446.6 KXT04046.1 - 0.054 13.1 10.1 0.82 9.3 2.0 2.6 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain FANCL_C PF11793.8 KXT04046.1 - 0.53 10.5 5.1 1.1 9.5 1.1 2.4 2 0 0 2 2 2 0 FANCL C-terminal domain C1_1 PF00130.22 KXT04046.1 - 0.59 10.1 14.5 1.1 9.3 1.9 2.6 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H_2 PF13832.6 KXT04046.1 - 3 8.1 5.4 1.8 8.8 0.5 2.3 2 0 0 2 2 2 0 PHD-zinc-finger like domain Mo25 PF08569.11 KXT04047.1 - 3.3e-121 404.6 0.3 3.8e-121 404.5 0.3 1.0 1 0 0 1 1 1 1 Mo25-like STE PF02200.16 KXT04047.1 - 0.035 14.5 0.1 15 6.0 0.1 2.4 2 0 0 2 2 2 0 STE like transcription factor Peptidase_M24 PF00557.24 KXT04048.1 - 1.5e-06 28.1 0.0 2.2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 RNA_pol_3_Rpc31 PF11705.8 KXT04048.1 - 0.013 15.7 5.3 0.013 15.7 5.3 1.8 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Trans_coact PF16805.5 KXT04048.1 - 0.28 11.3 2.7 1.8 8.8 0.0 2.7 3 0 0 3 3 3 0 Phage late-transcription coactivator Ribosomal_60s PF00428.19 KXT04048.1 - 0.46 11.1 13.0 1.9 9.1 13.0 2.0 1 0 0 1 1 1 0 60s Acidic ribosomal protein Pox_Ag35 PF03286.14 KXT04048.1 - 0.65 9.8 13.2 1.4 8.7 13.2 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein ANAPC15 PF15243.6 KXT04048.1 - 1 9.8 11.0 1.9 8.9 11.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 WRNPLPNID PF15017.6 KXT04048.1 - 3 8.8 9.3 3.7 8.5 8.0 1.9 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box RXT2_N PF08595.11 KXT04048.1 - 4.3 7.4 10.9 39 4.2 8.5 2.5 2 0 0 2 2 2 0 RXT2-like, N-terminal HATPase_c PF02518.26 KXT04049.1 - 3.7e-26 91.8 0.3 7e-26 90.9 0.3 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.12 KXT04049.1 - 8.1e-20 70.9 1.1 1.1e-11 44.9 0.5 3.7 3 0 0 3 3 3 3 PAS fold Response_reg PF00072.24 KXT04049.1 - 1.4e-18 67.1 0.0 3.8e-18 65.7 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KXT04049.1 - 1.4e-17 63.4 0.1 3.6e-17 62.2 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 KXT04049.1 - 1.1e-12 48.0 0.0 3.4e-06 27.0 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 KXT04049.1 - 3.7e-12 46.4 0.0 6.4e-08 32.8 0.0 3.6 3 0 0 3 3 3 2 PAS domain PAS_4 PF08448.10 KXT04049.1 - 3.7e-11 43.3 0.7 2.8e-08 34.0 0.0 3.6 4 0 0 4 4 4 2 PAS fold PAS_8 PF13188.7 KXT04049.1 - 0.00016 21.6 0.0 0.17 12.0 0.0 2.7 2 0 0 2 2 2 2 PAS domain His_biosynth PF00977.21 KXT04050.1 - 4.7e-47 160.4 0.2 3.4e-46 157.6 0.2 2.3 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 KXT04050.1 - 5.6e-23 81.7 0.0 9.4e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 KXT04050.1 - 1.6e-09 37.9 0.0 3.1e-08 33.7 0.0 2.2 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 KXT04050.1 - 9.7e-06 25.3 0.0 2.6e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Dus PF01207.17 KXT04050.1 - 0.0019 17.4 0.1 0.0036 16.4 0.1 1.4 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Peptidase_C26 PF07722.13 KXT04050.1 - 0.004 17.0 0.1 0.023 14.5 0.1 2.1 1 1 0 1 1 1 1 Peptidase C26 DUF1993 PF09351.10 KXT04051.1 - 1.3e-56 191.1 0.0 1.5e-56 191.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) NTP_transf_2 PF01909.23 KXT04052.1 - 0.00055 20.2 0.0 0.0013 19.0 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain DNA_pol_phi PF04931.13 KXT04053.1 - 5.8 4.9 20.8 10 4.1 20.8 1.3 1 0 0 1 1 1 0 DNA polymerase phi PS-DH PF14765.6 KXT04055.1 - 9.3e-67 225.4 0.0 1.5e-66 224.7 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 KXT04055.1 - 7.7e-63 211.7 0.2 2.5e-62 210.0 0.2 2.0 1 0 0 1 1 1 1 KR domain ketoacyl-synt PF00109.26 KXT04055.1 - 2.6e-58 197.6 0.7 1e-57 195.6 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KXT04055.1 - 1.4e-57 195.6 0.1 2.3e-57 194.9 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXT04055.1 - 4.3e-34 117.1 0.1 1.2e-33 115.6 0.1 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KXT04055.1 - 7.1e-27 94.1 0.0 2.2e-26 92.5 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 KXT04055.1 - 4.8e-13 49.2 0.1 2e-12 47.2 0.1 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXT04055.1 - 9.5e-11 42.9 0.0 5.4e-10 40.4 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 KXT04055.1 - 6.5e-09 35.5 0.7 2e-07 30.6 0.1 2.5 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_12 PF08242.12 KXT04055.1 - 2.9e-07 31.1 0.0 7.9e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KXT04055.1 - 9.8e-07 29.0 0.1 2.7e-06 27.6 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.6 KXT04055.1 - 3.8e-06 26.8 0.0 1.1e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 KXT04055.1 - 7e-06 25.8 0.4 0.00028 20.5 0.1 3.5 5 0 0 5 5 5 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_31 PF13847.6 KXT04055.1 - 3.4e-05 23.7 0.0 7.7e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.12 KXT04055.1 - 0.00078 19.3 0.0 0.002 18.0 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Collagen PF01391.18 KXT04055.1 - 0.0077 16.0 3.6 0.02 14.7 3.6 1.7 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Methyltransf_11 PF08241.12 KXT04055.1 - 0.044 14.4 0.0 0.18 12.5 0.0 2.1 1 0 0 1 1 1 0 Methyltransferase domain Zn_clus PF00172.18 KXT04056.1 - 1.5e-08 34.6 11.8 2.8e-08 33.8 11.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Exo5 PF09810.9 KXT04057.1 - 1.1e-125 420.0 0.1 1.1e-125 420.0 0.1 1.5 2 0 0 2 2 2 1 Exonuclease V - a 5' deoxyribonuclease L_lactis_ph-MCP PF06673.11 KXT04057.1 - 0.079 11.9 0.1 0.36 9.8 0.0 1.9 1 1 1 2 2 2 0 Lactococcus lactis bacteriophage major capsid protein Mpv17_PMP22 PF04117.12 KXT04058.1 - 2.1e-14 53.5 1.2 2.1e-14 53.5 1.2 2.2 2 0 0 2 2 2 1 Mpv17 / PMP22 family Fer4 PF00037.27 KXT04059.1 - 4.2e-14 51.7 15.9 3.7e-08 32.9 4.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KXT04059.1 - 4.9e-13 49.5 10.5 7.8e-13 48.8 10.5 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KXT04059.1 - 1e-10 42.4 7.5 1.7e-05 25.6 0.4 2.4 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 KXT04059.1 - 4.8e-10 39.4 21.9 3.7e-07 30.1 12.4 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KXT04059.1 - 7.8e-10 38.8 21.2 7.1e-08 32.5 11.2 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 KXT04059.1 - 1e-09 38.4 5.1 0.00012 22.1 0.4 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 KXT04059.1 - 7.4e-07 29.5 19.7 0.00032 21.1 11.7 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 KXT04059.1 - 1.8e-06 27.8 17.5 0.0004 20.3 5.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 KXT04059.1 - 5.3e-06 26.2 12.5 0.011 15.8 2.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 KXT04059.1 - 2.4e-05 24.5 11.5 0.0003 21.1 1.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 KXT04059.1 - 0.00013 22.4 12.0 0.023 15.2 2.0 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 KXT04059.1 - 0.023 14.9 6.1 0.79 10.0 0.3 2.3 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_13 PF13370.6 KXT04059.1 - 0.05 14.2 15.4 0.74 10.4 4.3 2.7 2 1 1 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 KXT04059.1 - 0.057 13.6 9.3 1.3 9.2 1.5 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 KXT04059.1 - 0.069 14.1 15.7 0.12 13.4 3.5 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain ETF_QO PF05187.13 KXT04059.1 - 0.094 12.9 5.9 0.4 10.8 0.6 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_22 PF17179.4 KXT04059.1 - 0.41 11.5 11.7 2.4 9.1 1.9 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain PhyH PF05721.13 KXT04060.1 - 1.4e-32 113.6 0.0 2e-32 113.2 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 KXT04060.1 - 0.1 13.0 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Neur_chan_memb PF02932.16 KXT04062.1 - 0.0091 16.1 0.1 0.012 15.7 0.1 1.3 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region MFS_1 PF07690.16 KXT04063.1 - 3.6e-28 98.5 62.0 4.9e-27 94.8 60.6 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXT04063.1 - 4.9e-12 45.4 7.7 4.9e-12 45.4 7.7 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter DUF3522 PF12036.8 KXT04063.1 - 0.0071 16.6 1.5 0.0071 16.6 1.5 2.6 2 2 0 2 2 2 1 Protein of unknown function (DUF3522) DUF4574 PF15141.6 KXT04063.1 - 3.1 7.8 4.2 4 7.4 0.0 3.0 2 1 0 3 3 3 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 Cnd1_N PF12922.7 KXT04064.1 - 3.8e-54 183.0 0.1 3.8e-54 183.0 0.1 2.5 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.7 KXT04064.1 - 6.6e-49 166.1 2.0 1e-42 145.9 0.1 4.1 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KXT04064.1 - 6.5e-10 39.3 0.6 0.012 16.0 0.0 5.7 5 1 1 6 6 6 2 HEAT repeats HEAT PF02985.22 KXT04064.1 - 3.5e-06 26.8 6.0 0.047 14.0 0.0 7.1 7 1 0 7 7 7 1 HEAT repeat RTP1_C1 PF10363.9 KXT04064.1 - 0.00023 21.3 0.2 0.094 12.9 0.0 3.9 3 1 1 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 KXT04064.1 - 0.00058 18.5 1.9 0.011 14.3 0.1 3.0 2 1 0 2 2 2 1 Adaptin N terminal region CLASP_N PF12348.8 KXT04064.1 - 0.28 10.7 2.5 4.5 6.8 0.1 3.6 3 2 1 5 5 5 0 CLASP N terminal HEAT_EZ PF13513.6 KXT04064.1 - 0.68 10.5 6.6 32 5.1 0.0 4.8 5 0 0 5 5 5 0 HEAT-like repeat PHF12_MRG_bd PF16737.5 KXT04065.1 - 0.14 11.9 0.0 0.37 10.5 0.0 1.7 2 0 0 2 2 2 0 PHD finger protein 12 MRG binding domain Elongin_A PF06881.11 KXT04066.1 - 2e-23 82.9 2.5 2e-23 82.9 2.5 2.5 2 1 0 3 3 3 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Gar1 PF04410.14 KXT04068.1 - 6.4e-46 155.9 1.0 6.4e-46 155.9 1.0 1.7 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region YL1 PF05764.13 KXT04068.1 - 0.16 12.1 11.2 2.3 8.3 5.1 2.3 2 0 0 2 2 2 0 YL1 nuclear protein DUF4692 PF15763.5 KXT04068.1 - 0.94 9.9 3.8 2.2 8.7 3.8 1.6 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) FAD_binding_4 PF01565.23 KXT04070.1 - 2.3e-21 76.0 0.7 4.1e-21 75.2 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain SWI-SNF_Ssr4 PF08549.10 KXT04071.1 - 7.4e-166 553.8 14.7 9.1e-166 553.5 14.7 1.1 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1750) Integrin_alpha2 PF08441.12 KXT04071.1 - 0.096 11.6 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Integrin alpha APG9 PF04109.16 KXT04072.1 - 9.8e-176 585.5 8.7 1.2e-175 585.2 8.7 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 MCM PF00493.23 KXT04073.1 - 2.7e-101 337.4 0.0 4.3e-101 336.7 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KXT04073.1 - 4.2e-38 130.1 0.0 7.5e-38 129.2 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 KXT04073.1 - 1.9e-29 102.9 31.0 1.9e-29 102.9 31.0 1.9 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 KXT04073.1 - 1.4e-25 89.5 0.6 4.1e-25 88.0 0.6 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KXT04073.1 - 3.8e-14 53.1 0.0 1.6e-13 51.2 0.0 2.0 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 KXT04073.1 - 2.7e-08 33.5 0.0 2.7e-06 26.9 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KXT04073.1 - 3e-06 27.3 0.0 6.7e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KXT04073.1 - 0.00042 20.2 0.1 0.0015 18.4 0.0 1.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KXT04073.1 - 0.0014 18.4 0.1 0.011 15.5 0.1 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain DUF3824 PF12868.7 KXT04074.1 - 5.5e-36 124.5 36.0 5.5e-36 124.5 36.0 11.3 4 3 6 10 10 10 3 Domain of unknwon function (DUF3824) Voltage_CLC PF00654.20 KXT04074.1 - 0.9 8.7 2.3 1.4 8.1 0.8 2.0 2 0 0 2 2 2 0 Voltage gated chloride channel DUF533 PF04391.12 KXT04074.1 - 7.2 6.1 8.3 16 5.0 0.5 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF533) DUF3824 PF12868.7 KXT04075.1 - 5.3e-36 124.5 36.0 5.3e-36 124.5 36.0 11.2 4 3 6 10 10 10 3 Domain of unknwon function (DUF3824) Voltage_CLC PF00654.20 KXT04075.1 - 0.86 8.8 2.3 1.4 8.1 0.8 2.0 2 0 0 2 2 2 0 Voltage gated chloride channel DUF533 PF04391.12 KXT04075.1 - 3.4 7.2 7.2 13 5.3 0.4 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF533) PhzC-PhzF PF02567.16 KXT04077.1 - 1.5e-41 142.7 0.0 1.8e-41 142.5 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pyr_redox_2 PF07992.14 KXT04078.1 - 2.7e-67 227.1 8.2 3.6e-67 226.7 7.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KXT04078.1 - 1.1e-39 135.1 0.6 2.6e-39 133.9 0.1 2.0 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KXT04078.1 - 8.7e-23 80.7 7.8 2.6e-19 69.5 0.5 3.1 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXT04078.1 - 1.8e-10 40.9 6.0 8e-07 29.2 0.3 2.8 3 0 0 3 3 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KXT04078.1 - 7.7e-10 38.7 0.6 7.7e-10 38.7 0.6 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 KXT04078.1 - 2.2e-08 33.6 10.9 6.1e-07 28.9 5.2 2.7 2 1 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KXT04078.1 - 3.8e-08 32.9 6.0 7e-06 25.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KXT04078.1 - 7.7e-08 31.9 3.5 0.0037 16.6 0.2 2.6 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 KXT04078.1 - 3.5e-07 29.6 2.5 3.5e-07 29.6 2.5 2.8 4 0 0 4 4 4 1 FAD binding domain K_oxygenase PF13434.6 KXT04078.1 - 5.2e-07 29.1 0.9 0.034 13.3 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 KXT04078.1 - 2.9e-06 26.2 14.4 6.5e-05 21.8 1.7 4.1 4 0 0 4 4 4 1 HI0933-like protein Thi4 PF01946.17 KXT04078.1 - 2e-05 24.0 2.5 3.8e-05 23.1 0.1 2.2 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 KXT04078.1 - 4.5e-05 23.2 14.1 0.0019 17.8 0.6 3.9 4 0 0 4 4 4 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KXT04078.1 - 0.0011 18.1 3.2 0.0099 15.0 0.3 2.6 2 1 0 2 2 2 1 Lycopene cyclase protein NAD_binding_7 PF13241.6 KXT04078.1 - 0.0034 17.8 0.8 3.6 8.1 0.1 2.7 2 0 0 2 2 2 2 Putative NAD(P)-binding FAD_binding_3 PF01494.19 KXT04078.1 - 0.0084 15.4 8.3 0.2 10.8 1.2 3.2 2 1 0 2 2 2 2 FAD binding domain 3HCDH_N PF02737.18 KXT04078.1 - 0.018 14.9 3.3 0.13 12.1 0.6 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KXT04078.1 - 0.08 12.3 0.6 8.8 5.6 0.2 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Trp_halogenase PF04820.14 KXT04078.1 - 0.098 11.5 5.3 0.078 11.8 0.6 2.3 2 0 0 2 2 2 0 Tryptophan halogenase UDPG_MGDP_dh_N PF03721.14 KXT04078.1 - 0.14 11.7 3.9 0.79 9.3 0.2 2.6 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FMO-like PF00743.19 KXT04078.1 - 0.86 8.0 5.0 0.33 9.3 1.5 1.9 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like Glyco_transf_20 PF00982.21 KXT04080.1 - 8e-148 493.0 0.0 1.2e-147 492.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KXT04080.1 - 2.6e-84 282.0 0.0 6.1e-84 280.8 0.0 1.6 2 0 0 2 2 2 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 KXT04080.1 - 0.00021 21.1 0.0 0.11 12.2 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Glyco_transf_5 PF08323.11 KXT04080.1 - 0.1 12.3 0.1 0.24 11.1 0.1 1.6 1 0 0 1 1 1 0 Starch synthase catalytic domain DUF4121 PF13497.6 KXT04080.1 - 0.13 11.4 0.8 0.28 10.3 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4121) Glyco_transf_20 PF00982.21 KXT04081.1 - 8e-148 493.0 0.0 1.2e-147 492.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KXT04081.1 - 2.6e-84 282.0 0.0 6.1e-84 280.8 0.0 1.6 2 0 0 2 2 2 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 KXT04081.1 - 0.00021 21.1 0.0 0.11 12.2 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Glyco_transf_5 PF08323.11 KXT04081.1 - 0.1 12.3 0.1 0.24 11.1 0.1 1.6 1 0 0 1 1 1 0 Starch synthase catalytic domain DUF4121 PF13497.6 KXT04081.1 - 0.13 11.4 0.8 0.28 10.3 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4121) CorA PF01544.18 KXT04084.1 - 7.2e-13 48.5 0.1 1.1e-12 47.8 0.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Zn_clus PF00172.18 KXT04085.1 - 1.5e-09 37.8 9.2 2.5e-09 37.1 9.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KXT04086.1 - 4.7e-31 108.0 24.4 9.2e-31 107.0 17.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_20 PF00728.22 KXT04088.1 - 3.5e-87 293.1 2.0 4.3e-87 292.8 2.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 KXT04088.1 - 1.6e-27 96.8 0.0 3.4e-27 95.8 0.0 1.6 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 KXT04088.1 - 8.4e-10 39.5 0.1 7.5e-09 36.4 0.1 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 DUF3445 PF11927.8 KXT04089.1 - 2.1e-77 259.7 0.0 2.7e-77 259.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Glyco_transf_90 PF05686.12 KXT04089.1 - 0.052 12.4 0.0 0.076 11.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 90 DUF3445 PF11927.8 KXT04090.1 - 2.1e-77 259.7 0.0 2.7e-77 259.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Glyco_transf_90 PF05686.12 KXT04090.1 - 0.052 12.4 0.0 0.076 11.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 90 adh_short PF00106.25 KXT04091.1 - 3.8e-17 62.4 0.0 1.7e-16 60.2 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXT04091.1 - 2e-10 40.9 0.4 9.9e-10 38.6 0.0 2.0 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 KXT04091.1 - 3.1e-06 27.2 0.4 9.5e-06 25.6 0.1 2.0 2 1 0 2 2 2 1 NAD(P)H-binding F420_oxidored PF03807.17 KXT04091.1 - 3.4e-06 27.5 0.1 8.8e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent adh_short_C2 PF13561.6 KXT04091.1 - 4.1e-05 23.3 1.6 0.00076 19.1 1.3 2.8 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ApbA PF02558.16 KXT04091.1 - 0.0024 17.5 0.0 0.0042 16.8 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Epimerase PF01370.21 KXT04091.1 - 0.0048 16.4 0.0 0.012 15.1 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KXT04091.1 - 0.0048 16.8 0.0 0.023 14.6 0.0 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KXT04091.1 - 0.0095 16.2 0.1 0.019 15.2 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 KXT04091.1 - 0.022 14.9 0.0 0.041 14.1 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NmrA PF05368.13 KXT04091.1 - 0.041 13.5 0.0 0.14 11.6 0.0 1.8 2 0 0 2 2 2 0 NmrA-like family GDP_Man_Dehyd PF16363.5 KXT04091.1 - 0.088 12.2 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DFP PF04127.15 KXT04091.1 - 0.092 12.6 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Polysacc_synt_2 PF02719.15 KXT04091.1 - 0.096 11.8 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KXT04091.1 - 0.1 11.7 0.1 0.16 11.0 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_Gly3P_dh_N PF01210.23 KXT04091.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.18 KXT04091.1 - 0.15 12.3 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain ubiquitin PF00240.23 KXT04092.1 - 7.8e-26 89.6 0.1 8.7e-26 89.5 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KXT04092.1 - 1.3e-15 57.0 0.1 1.4e-15 56.8 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KXT04092.1 - 1.3e-05 25.5 0.1 4.3e-05 23.9 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KXT04092.1 - 0.00035 20.4 0.0 0.00041 20.2 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KXT04092.1 - 0.089 12.9 0.1 0.27 11.4 0.1 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 KXT04092.1 - 0.24 11.5 0.4 5 7.2 0.2 2.0 2 0 0 2 2 2 0 Ubiquitin-like domain MFS_1 PF07690.16 KXT04094.1 - 5.5e-10 38.7 0.5 7e-10 38.4 0.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXT04094.1 - 0.00016 20.7 0.0 0.00022 20.2 0.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter CENP-T_C PF15511.6 KXT04095.1 - 8e-09 35.6 0.1 9.7e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 KXT04095.1 - 2.4e-05 24.7 0.1 2.8e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 KXT04095.1 - 7.2e-05 22.9 0.1 0.0001 22.4 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KXT04095.1 - 0.0002 21.6 0.1 0.00035 20.8 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 KXT04095.1 - 0.0004 20.7 0.1 0.00056 20.2 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 KXT04095.1 - 0.0085 16.2 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KXT04095.1 - 0.031 14.3 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 KXT04095.1 - 0.052 13.3 0.2 0.064 13.0 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) HIGH_NTase1_ass PF16581.5 KXT04095.1 - 0.11 12.5 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region THOC7 PF05615.13 KXT04096.1 - 1.1e-35 122.7 6.1 1.1e-35 122.7 6.1 2.0 1 1 1 2 2 2 1 Tho complex subunit 7 DUF241 PF03087.14 KXT04096.1 - 0.0011 18.9 2.8 0.0019 18.1 2.8 1.4 1 0 0 1 1 1 1 Arabidopsis protein of unknown function TPR_MLP1_2 PF07926.12 KXT04096.1 - 0.025 14.6 11.4 0.043 13.9 11.4 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Rootletin PF15035.6 KXT04096.1 - 0.029 14.4 8.3 0.049 13.7 8.3 1.4 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion NFRKB_winged PF14465.6 KXT04096.1 - 0.04 14.1 0.1 1.3 9.2 0.0 2.4 2 0 0 2 2 2 0 NFRKB Winged Helix-like CorA PF01544.18 KXT04096.1 - 1.8 7.8 6.9 3.5 6.9 6.9 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein HAD_2 PF13419.6 KXT04097.1 - 3.7e-10 40.2 0.0 7.4e-10 39.2 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXT04097.1 - 2.6e-09 37.7 0.0 4e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXT04097.1 - 5.6e-07 29.5 0.0 1.3e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Mpt_N PF09176.11 KXT04097.1 - 0.1 12.7 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal TBCA PF02970.16 KXT04098.1 - 1.7e-26 92.4 8.5 2.1e-26 92.1 8.5 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor A DUF2570 PF10828.8 KXT04098.1 - 0.076 12.8 5.5 0.092 12.6 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) HSP70 PF00012.20 KXT04098.1 - 0.28 9.3 6.9 0.32 9.1 6.9 1.0 1 0 0 1 1 1 0 Hsp70 protein Tho2 PF11262.8 KXT04098.1 - 0.92 8.6 5.0 1 8.5 5.0 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 V_ATPase_I PF01496.19 KXT04098.1 - 3 5.6 5.8 3.1 5.6 5.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 KXT04098.1 - 3.4 6.9 8.8 4.8 6.5 8.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Inp1 PF12634.7 KXT04099.1 - 1.8e-39 134.9 0.1 1.4e-38 132.0 0.0 2.6 3 0 0 3 3 3 1 Inheritance of peroxisomes protein 1 NAM-associated PF14303.6 KXT04099.1 - 0.6 10.8 0.0 0.6 10.8 0.0 3.6 2 2 0 4 4 4 0 No apical meristem-associated C-terminal domain Pkinase PF00069.25 KXT04100.1 - 6.4e-45 153.6 0.0 4.6e-21 75.4 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KXT04100.1 - 1.5e-13 50.7 0.0 7.9e-10 38.4 0.0 3.6 2 2 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KXT04100.1 - 0.0082 16.1 0.0 0.68 9.8 0.0 2.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXT04100.1 - 0.015 14.1 0.0 0.029 13.1 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KXT04100.1 - 0.06 12.7 0.8 0.16 11.3 0.1 2.0 2 1 1 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family Stm1_N PF09598.10 KXT04100.1 - 0.07 14.0 1.2 0.29 12.0 1.2 2.1 1 0 0 1 1 1 0 Stm1 DNA_pol_phi PF04931.13 KXT04100.1 - 0.54 8.3 10.0 0.98 7.4 10.0 1.3 1 0 0 1 1 1 0 DNA polymerase phi Histone PF00125.24 KXT04101.1 - 4e-52 176.0 2.5 4.5e-52 175.9 2.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KXT04101.1 - 6e-06 26.6 0.0 9e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 KXT04101.1 - 4e-05 24.2 1.2 4.7e-05 24.0 1.2 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 KXT04101.1 - 4.3e-05 23.6 0.4 7.4e-05 22.8 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KXT04101.1 - 0.0038 17.5 0.4 0.0065 16.7 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KXT04101.1 - 0.026 14.6 0.2 0.042 13.9 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Aminotran_1_2 PF00155.21 KXT04102.1 - 4.8e-42 144.4 0.0 6.7e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KXT04102.1 - 2.5e-06 26.3 0.0 3.5e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme MCM PF00493.23 KXT04103.1 - 5.2e-100 333.2 0.0 9.2e-100 332.3 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KXT04103.1 - 6.9e-39 132.6 0.9 1.3e-38 131.7 0.9 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KXT04103.1 - 9.6e-30 102.9 3.1 1.9e-29 101.9 3.1 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KXT04103.1 - 2.6e-13 50.5 0.0 1.3e-12 48.2 0.0 2.2 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.14 KXT04103.1 - 4.4e-06 26.7 0.3 0.00012 22.1 0.0 2.8 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KXT04103.1 - 1.3e-05 24.7 0.0 0.00027 20.4 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KXT04103.1 - 0.00066 19.6 0.0 0.0018 18.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KXT04103.1 - 0.1 12.3 0.1 3.5 7.3 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_32 PF13654.6 KXT04103.1 - 0.53 9.0 2.6 0.29 9.9 0.2 1.7 2 0 0 2 2 2 0 AAA domain Ras PF00071.22 KXT04104.1 - 4.3e-53 179.2 0.2 1.5e-52 177.5 0.2 1.7 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KXT04104.1 - 2.4e-19 69.7 0.0 2.2e-17 63.4 0.0 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXT04104.1 - 5.7e-05 22.6 0.0 0.00046 19.7 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KXT04104.1 - 0.01 15.4 0.4 0.46 10.0 0.4 2.9 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KXT04104.1 - 0.059 13.3 0.0 12 5.8 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase Septin PF00735.18 KXT04104.1 - 0.068 12.4 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Septin MMR_HSR1 PF01926.23 KXT04104.1 - 0.073 13.1 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase PAG PF15347.6 KXT04104.1 - 0.096 11.7 0.9 0.13 11.2 0.9 1.1 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched AAA_16 PF13191.6 KXT04104.1 - 0.15 12.4 0.3 0.35 11.2 0.3 1.8 1 1 0 1 1 1 0 AAA ATPase domain Cu_amine_oxid PF01179.20 KXT04105.1 - 1.9e-161 537.6 0.1 2.4e-161 537.3 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KXT04105.1 - 0.00055 20.3 0.0 0.0012 19.2 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KXT04105.1 - 0.00095 19.4 0.0 0.0025 18.0 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Aminotran_1_2 PF00155.21 KXT04106.1 - 1.6e-21 76.9 0.0 2.8e-12 46.5 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KXT04106.1 - 1.7e-05 23.6 0.0 2.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KXT04106.1 - 0.0086 15.4 0.2 0.02 14.2 0.1 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 KXT04106.1 - 0.025 13.9 0.1 0.038 13.3 0.1 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase OKR_DC_1 PF01276.20 KXT04106.1 - 0.035 12.8 0.0 0.066 11.9 0.0 1.3 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Aminotran_5 PF00266.19 KXT04106.1 - 0.055 12.4 0.0 0.15 11.0 0.0 1.6 2 0 0 2 2 2 0 Aminotransferase class-V SHMT PF00464.19 KXT04106.1 - 0.14 10.7 0.0 0.57 8.7 0.0 1.7 1 1 1 2 2 2 0 Serine hydroxymethyltransferase RED_N PF07808.13 KXT04107.1 - 1.6e-05 24.6 7.1 1.6e-05 24.6 7.1 3.1 2 1 1 3 3 3 1 RED-like protein N-terminal region p450 PF00067.22 KXT04108.1 - 6.2e-68 229.6 0.0 7.8e-68 229.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SapB_1 PF05184.15 KXT04108.1 - 0.11 12.5 0.1 0.22 11.6 0.1 1.5 1 0 0 1 1 1 0 Saposin-like type B, region 1 FmdA_AmdA PF03069.15 KXT04109.1 - 9.8e-169 561.1 0.0 1.3e-168 560.6 0.0 1.1 1 0 0 1 1 1 1 Acetamidase/Formamidase family EI24 PF07264.11 KXT04109.1 - 4.7e-11 43.3 3.1 7.2e-09 36.1 3.1 2.2 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Fungal_trans_2 PF11951.8 KXT04110.1 - 3.7e-50 170.8 2.5 5.2e-50 170.4 2.5 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT04110.1 - 2.3e-10 40.4 10.7 4.4e-10 39.5 10.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.19 KXT04110.1 - 0.35 10.9 4.2 0.82 9.8 4.2 1.6 1 0 0 1 1 1 0 AT hook motif Endosulfine PF04667.17 KXT04138.1 - 3.3e-32 110.4 0.3 3.3e-32 110.4 0.3 1.5 2 0 0 2 2 2 1 cAMP-regulated phosphoprotein/endosulfine conserved region Endonuclease_NS PF01223.23 KXT04139.1 - 4.8e-65 219.5 0.0 5.9e-65 219.2 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease DUF2555 PF10742.9 KXT04140.1 - 0.12 12.2 0.0 0.39 10.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2555) WD40 PF00400.32 KXT04141.1 - 4.2e-34 116.0 14.9 1.2e-06 29.2 0.7 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXT04141.1 - 1e-15 57.8 0.1 0.0054 17.0 0.0 5.4 3 1 3 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXT04141.1 - 0.00012 22.1 0.0 2.2 8.1 0.0 3.6 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KXT04141.1 - 0.012 14.6 0.3 1.9 7.4 0.3 3.4 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein EpmC PF04315.12 KXT04141.1 - 0.13 12.0 0.3 0.25 11.0 0.3 1.4 1 0 0 1 1 1 0 Elongation factor P hydroxylase Nbas_N PF15492.6 KXT04141.1 - 0.15 11.4 0.2 8.1 5.7 0.0 3.2 2 2 2 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Frtz PF11768.8 KXT04141.1 - 0.2 10.0 0.0 0.64 8.3 0.0 1.8 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz WD40 PF00400.32 KXT04142.1 - 4.2e-34 116.0 14.9 1.2e-06 29.2 0.7 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXT04142.1 - 1e-15 57.8 0.1 0.0054 17.0 0.0 5.4 3 1 3 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXT04142.1 - 0.00012 22.1 0.0 2.2 8.1 0.0 3.6 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KXT04142.1 - 0.012 14.6 0.3 1.9 7.4 0.3 3.4 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein EpmC PF04315.12 KXT04142.1 - 0.13 12.0 0.3 0.25 11.0 0.3 1.4 1 0 0 1 1 1 0 Elongation factor P hydroxylase Nbas_N PF15492.6 KXT04142.1 - 0.15 11.4 0.2 8.1 5.7 0.0 3.2 2 2 2 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Frtz PF11768.8 KXT04142.1 - 0.2 10.0 0.0 0.64 8.3 0.0 1.8 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Glyco_hydro_43 PF04616.14 KXT04143.1 - 1.9e-10 40.6 2.8 4.3e-10 39.4 2.8 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 WD40 PF00400.32 KXT04144.1 - 2.7e-38 129.3 18.8 9.4e-10 38.9 0.1 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXT04144.1 - 6e-13 48.9 0.3 0.0029 17.8 0.1 4.9 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXT04144.1 - 2.5e-08 33.3 0.1 0.18 10.8 0.0 4.2 1 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KXT04144.1 - 0.00052 18.8 2.6 0.18 10.4 0.1 4.4 3 1 0 4 4 4 1 Nucleoporin Nup120/160 Frtz PF11768.8 KXT04144.1 - 0.0038 15.6 0.0 0.0078 14.6 0.0 1.4 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz DUF1513 PF07433.11 KXT04144.1 - 0.0055 15.8 0.7 2.6 7.0 0.0 3.1 1 1 1 3 3 3 2 Protein of unknown function (DUF1513) PALB2_WD40 PF16756.5 KXT04144.1 - 0.02 13.9 0.1 0.02 13.9 0.1 2.7 4 0 0 4 4 4 0 Partner and localizer of BRCA2 WD40 domain Coatomer_WDAD PF04053.14 KXT04144.1 - 0.028 13.5 0.0 0.072 12.1 0.0 1.7 1 1 0 1 1 1 0 Coatomer WD associated region HPS3_N PF14761.6 KXT04144.1 - 0.082 12.4 0.0 0.25 10.8 0.0 1.8 1 1 0 2 2 2 0 Hermansky-Pudlak syndrome 3 Alpha_L_fucos PF01120.17 KXT04145.1 - 5.4e-80 269.5 4.4 9e-80 268.7 4.4 1.3 1 0 0 1 1 1 1 Alpha-L-fucosidase CDC37_N PF03234.14 KXT04145.1 - 3.6e-46 157.3 1.0 3.6e-46 157.3 1.0 3.1 4 0 0 4 4 4 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 KXT04145.1 - 2.9e-34 117.5 0.6 1.3e-33 115.4 0.6 2.1 1 1 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 KXT04145.1 - 8.8e-30 102.8 0.1 3.4e-29 100.9 0.1 2.0 1 0 0 1 1 1 1 Cdc37 C terminal domain DUF2799 PF10973.8 KXT04145.1 - 0.77 10.2 3.8 1.5 9.3 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2799) Spectrin PF00435.21 KXT04145.1 - 3.1 8.3 6.0 29 5.2 0.5 3.5 3 0 0 3 3 3 0 Spectrin repeat DDOST_48kD PF03345.14 KXT04146.1 - 1e-157 525.3 0.0 1.3e-157 524.9 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Asp PF00026.23 KXT04146.1 - 4.4e-66 223.4 6.9 9e-66 222.4 6.9 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXT04146.1 - 7.1e-11 42.7 4.6 1.3e-10 41.8 1.3 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal PseudoU_synth_1 PF01416.20 KXT04147.1 - 3.7e-07 30.6 0.0 3.1e-06 27.6 0.0 2.4 2 0 0 2 2 2 1 tRNA pseudouridine synthase DUF4441 PF14536.6 KXT04147.1 - 0.1 12.8 1.2 0.17 12.1 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4441) WD40 PF00400.32 KXT04148.1 - 3.4e-17 62.5 3.7 8.2e-05 23.3 0.0 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXT04148.1 - 0.0025 18.0 0.0 0.66 10.3 0.0 4.0 1 1 3 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PilX PF13681.6 KXT04148.1 - 0.015 15.6 0.1 0.044 14.1 0.1 2.0 1 1 0 1 1 1 0 Type IV pilus assembly protein PilX C-term Ge1_WD40 PF16529.5 KXT04148.1 - 0.018 14.0 0.2 0.17 10.8 0.0 2.7 2 2 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein FliO PF04347.13 KXT04148.1 - 0.12 12.7 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 Flagellar biosynthesis protein, FliO zf-C2H2_4 PF13894.6 KXT04149.1 - 2.7e-06 27.8 32.1 0.15 13.0 0.7 7.0 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2 PF00096.26 KXT04149.1 - 0.00021 21.5 29.5 0.0097 16.3 0.6 6.5 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 KXT04149.1 - 0.0026 18.4 9.5 0.093 13.4 4.6 2.9 1 1 2 3 3 3 2 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 KXT04149.1 - 1.9 9.0 16.8 7 7.2 2.2 4.8 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KXT04149.1 - 4.5 7.7 22.8 0.38 11.1 1.9 5.4 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KXT04149.1 - 9.4 6.6 12.2 16 5.9 2.5 3.5 2 2 1 3 3 3 0 C2H2 type zinc-finger (2 copies) DIE2_ALG10 PF04922.12 KXT04150.1 - 6.2e-120 401.1 15.9 7.4e-120 400.8 15.9 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family Dynamin_N PF00350.23 KXT04153.1 - 4.9e-34 117.8 1.1 8.1e-34 117.1 0.0 1.9 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 KXT04153.1 - 3.3e-27 95.4 5.0 1.6e-26 93.2 0.5 3.0 1 1 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 KXT04153.1 - 4.7e-05 23.4 0.0 0.00057 19.9 0.0 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase TMF_TATA_bd PF12325.8 KXT04153.1 - 0.034 14.4 0.2 0.034 14.4 0.2 3.2 4 0 0 4 4 4 0 TATA element modulatory factor 1 TATA binding AAA_15 PF13175.6 KXT04153.1 - 0.065 12.9 2.6 0.93 9.1 0.0 3.1 3 0 0 3 3 3 0 AAA ATPase domain HSP9_HSP12 PF04119.12 KXT04153.1 - 0.11 12.9 0.5 21 5.6 0.2 3.2 2 0 0 2 2 2 0 Heat shock protein 9/12 AAA_16 PF13191.6 KXT04153.1 - 0.12 12.8 7.1 0.6 10.5 0.0 3.9 3 1 2 5 5 5 0 AAA ATPase domain AAA_23 PF13476.6 KXT04153.1 - 3.5 8.1 9.2 3.6 8.0 0.0 3.4 3 1 0 3 3 3 0 AAA domain Hexapep PF00132.24 KXT04154.1 - 5e-09 35.5 6.7 7.3e-07 28.7 0.6 3.3 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KXT04154.1 - 1e-08 34.7 7.8 1.7e-07 30.8 0.5 3.1 2 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Zn_clus PF00172.18 KXT04154.1 - 2.9e-07 30.5 9.5 7.4e-07 29.2 9.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mac PF12464.8 KXT04154.1 - 0.0019 18.4 0.1 0.0046 17.2 0.1 1.7 1 0 0 1 1 1 1 Maltose acetyltransferase Metallophos_2 PF12850.7 KXT04155.1 - 6e-12 46.1 0.0 7.4e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain TauD PF02668.16 KXT04157.1 - 3.5e-24 86.0 0.1 7.7e-24 84.9 0.1 1.6 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family VSP PF03302.13 KXT04158.1 - 0.00069 18.6 0.6 0.001 18.0 0.6 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein Podoplanin PF05808.11 KXT04158.1 - 0.0015 18.6 0.8 0.0015 18.6 0.8 1.6 2 0 0 2 2 2 1 Podoplanin DcuC PF03606.15 KXT04158.1 - 0.08 11.4 0.4 0.11 10.9 0.4 1.1 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier Amnionless PF14828.6 KXT04158.1 - 0.2 10.4 0.1 0.27 10.0 0.1 1.1 1 0 0 1 1 1 0 Amnionless FSA_C PF10479.9 KXT04158.1 - 0.28 9.3 6.4 0.4 8.8 6.4 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus RRM_1 PF00076.22 KXT04159.1 - 3.6e-14 52.3 0.1 7.8e-14 51.3 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 KXT04159.1 - 0.053 13.5 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 RL domain UBX PF00789.20 KXT04160.1 - 1.2e-07 31.8 0.0 3.1e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 UBX domain UBA PF00627.31 KXT04160.1 - 6.6e-05 22.7 0.1 0.0002 21.2 0.0 2.0 2 0 0 2 2 2 1 UBA/TS-N domain zf-C2H2_2 PF12756.7 KXT04160.1 - 0.0044 17.3 0.3 0.0044 17.3 0.3 1.9 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) Atg14 PF10186.9 KXT04160.1 - 0.17 10.9 14.0 0.23 10.5 14.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 zf-C2HE PF16278.5 KXT04160.1 - 0.5 10.9 0.1 0.5 10.9 0.1 3.1 2 1 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Skp1 PF01466.19 KXT04160.1 - 3.5 7.8 13.5 0.12 12.5 5.5 2.7 2 0 0 2 2 2 0 Skp1 family, dimerisation domain SOBP PF15279.6 KXT04160.1 - 5.3 7.6 8.5 6.4 7.3 8.5 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein SAP PF02037.27 KXT04161.1 - 3.2e-06 26.8 0.4 7.8e-06 25.5 0.1 1.7 2 0 0 2 2 2 1 SAP domain Aminotran_5 PF00266.19 KXT04162.1 - 6.6e-28 97.7 0.0 8.3e-28 97.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cytochrom_B559a PF00284.20 KXT04162.1 - 0.075 12.8 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 Lumenal portion of Cytochrome b559, alpha (gene psbE) subunit Fungal_trans PF04082.18 KXT04163.1 - 6.8e-19 67.9 0.0 1.2e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT04163.1 - 0.003 17.6 13.0 0.0057 16.8 13.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sld5 PF05916.11 KXT04164.1 - 4.2e-26 91.6 0.0 7.7e-26 90.7 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein Nucleoporin_C PF03177.14 KXT04165.1 - 8.4e-127 424.4 13.6 1.1e-126 424.1 13.6 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 KXT04165.1 - 2.1e-39 135.5 0.0 3.1e-39 135.0 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Motile_Sperm PF00635.26 KXT04166.1 - 2.4e-25 88.5 0.0 5.1e-25 87.4 0.0 1.6 1 1 0 1 1 1 1 MSP (Major sperm protein) domain ASH PF15780.5 KXT04166.1 - 0.014 15.6 0.0 0.03 14.5 0.0 1.5 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PheRS_DBD3 PF18553.1 KXT04166.1 - 0.021 15.1 1.1 0.31 11.4 0.1 2.4 2 0 0 2 2 2 0 PheRS DNA binding domain 3 Podoplanin PF05808.11 KXT04167.1 - 0.031 14.4 0.0 0.052 13.7 0.0 1.3 1 0 0 1 1 1 0 Podoplanin PTP_tm PF18861.1 KXT04167.1 - 0.14 12.2 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J MLTD_N PF06474.12 KXT04167.1 - 0.28 11.4 2.2 0.92 9.7 0.1 3.0 4 0 0 4 4 4 0 MltD lipid attachment motif SMN PF06003.12 KXT04168.1 - 0.0012 18.1 11.5 0.0042 16.4 6.5 2.0 1 1 1 2 2 2 2 Survival motor neuron protein (SMN) SMN PF06003.12 KXT04169.1 - 0.0012 18.1 11.5 0.0042 16.4 6.5 2.0 1 1 1 2 2 2 2 Survival motor neuron protein (SMN) Orn_Arg_deC_N PF02784.16 KXT04170.1 - 7e-75 251.6 0.0 9.6e-75 251.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KXT04170.1 - 5e-17 61.9 0.0 6.6e-17 61.6 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.24 KXT04170.1 - 0.001 18.5 0.0 0.0031 17.0 0.0 1.7 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel DUF1815 PF08844.10 KXT04170.1 - 0.078 13.0 0.1 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1815) RGS PF00615.19 KXT04171.1 - 1.3e-11 44.8 0.0 1.9e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain ELFV_dehydrog PF00208.21 KXT04172.1 - 8e-86 287.7 4.6 9.8e-86 287.4 4.6 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 KXT04172.1 - 9.5e-52 174.3 0.0 2.4e-51 173.0 0.0 1.7 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.6 KXT04172.1 - 0.037 14.5 0.1 0.13 12.7 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding Acyl_transf_1 PF00698.21 KXT04174.1 - 2.8e-23 82.9 0.0 1.3e-17 64.3 0.0 2.1 1 1 1 2 2 2 2 Acyl transferase domain ROS_MUCR PF05443.11 KXT04174.1 - 0.0017 18.4 0.0 0.0041 17.2 0.0 1.6 1 0 0 1 1 1 1 ROS/MUCR transcriptional regulator protein Omega-toxin PF06357.11 KXT04175.1 - 0.85 9.5 5.0 6.2 6.7 0.4 2.5 1 1 1 2 2 2 0 Omega-atracotoxin IucA_IucC PF04183.12 KXT04176.1 - 8.7e-21 74.6 0.1 2.5e-16 60.0 0.0 2.5 2 0 0 2 2 2 2 IucA / IucC family FhuF PF06276.12 KXT04176.1 - 1.1e-19 71.4 0.0 2.7e-19 70.1 0.0 1.7 1 0 0 1 1 1 1 Ferric iron reductase FhuF-like transporter ERAP1_C PF11838.8 KXT04176.1 - 0.033 13.7 0.1 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 ERAP1-like C-terminal domain GH3 PF03321.13 KXT04176.1 - 0.066 12.1 0.1 0.12 11.2 0.1 1.4 1 0 0 1 1 1 0 GH3 auxin-responsive promoter Ribosomal_L3 PF00297.22 KXT04177.1 - 3.8e-21 75.5 3.6 9.9e-18 64.3 1.6 2.1 1 1 1 2 2 2 2 Ribosomal protein L3 LRR_6 PF13516.6 KXT04180.1 - 0.04 14.0 0.0 0.068 13.3 0.0 1.4 1 0 0 1 1 1 0 Leucine Rich repeat MCM_bind PF09739.9 KXT04182.1 - 0.14 10.6 2.3 0.18 10.2 2.3 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor MAP17 PF15807.5 KXT04182.1 - 0.18 12.1 1.5 0.32 11.2 1.5 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Otopetrin PF03189.13 KXT04182.1 - 0.19 10.5 0.0 0.21 10.4 0.0 1.1 1 0 0 1 1 1 0 Otopetrin HTH_11 PF08279.12 KXT04183.1 - 0.11 12.5 0.1 0.22 11.5 0.1 1.4 1 0 0 1 1 1 0 HTH domain Spc7 PF08317.11 KXT04183.1 - 0.27 10.1 2.3 0.35 9.7 2.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Trehalase PF01204.18 KXT04186.1 - 8.2e-08 31.5 0.0 1.2e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Trehalase Glyco_hydro_63 PF03200.16 KXT04186.1 - 0.0019 17.0 0.4 0.018 13.8 0.0 2.7 2 1 1 3 3 3 1 Glycosyl hydrolase family 63 C-terminal domain DUF2408 PF10303.9 KXT04188.1 - 3.5e-39 134.5 13.7 6.7e-24 85.0 4.1 5.0 3 2 1 4 4 4 4 Protein of unknown function (DUF2408) DUF3365 PF11845.8 KXT04188.1 - 0.0053 17.1 0.1 0.0091 16.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3365) RFX5_N PF18326.1 KXT04190.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 RFX5 N-terminal domain Ribosomal_60s PF00428.19 KXT04191.1 - 2.4e-26 92.1 10.9 3.3e-26 91.7 10.9 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein SOG2 PF10428.9 KXT04192.1 - 2.1e-15 57.0 7.6 2.5e-09 36.9 3.9 3.6 3 1 1 4 4 4 2 RAM signalling pathway protein LRR_8 PF13855.6 KXT04192.1 - 6e-11 41.9 0.9 1.1e-08 34.7 0.1 3.1 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KXT04192.1 - 3.4e-09 36.8 0.7 0.00082 19.7 0.0 3.9 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXT04192.1 - 7.7e-06 25.8 0.6 1.4 9.8 0.0 4.7 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.6 KXT04192.1 - 0.00046 20.0 0.2 3.6 7.9 0.1 3.9 4 0 0 4 4 4 2 Leucine Rich repeat Tmemb_170 PF10190.9 KXT04194.1 - 1.1e-22 80.3 9.7 1.3e-22 80.1 9.7 1.1 1 0 0 1 1 1 1 Putative transmembrane protein 170 Wzz PF02706.15 KXT04194.1 - 0.68 10.3 3.5 0.54 10.6 0.5 2.3 1 1 1 2 2 2 0 Chain length determinant protein Bacteriocin_IIc PF10439.9 KXT04194.1 - 3 8.0 10.3 9.1 6.5 10.3 1.9 1 1 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide FtsX PF02687.21 KXT04194.1 - 3.6 8.1 11.7 0.73 10.3 7.9 1.7 1 1 1 2 2 2 0 FtsX-like permease family NiFeSe_Hases PF00374.19 KXT04195.1 - 0.24 10.3 0.0 0.32 9.8 0.0 1.1 1 0 0 1 1 1 0 Nickel-dependent hydrogenase AAA_13 PF13166.6 KXT04196.1 - 0.0007 18.4 26.0 0.0007 18.4 26.0 12.5 2 1 3 9 9 9 2 AAA domain STAS_2 PF13466.6 KXT04197.1 - 0.03 14.7 0.0 0.067 13.5 0.0 1.6 1 0 0 1 1 1 0 STAS domain DAO PF01266.24 KXT04198.1 - 8.8e-46 157.1 0.0 1e-45 156.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXT04198.1 - 0.0013 18.9 0.0 0.0027 17.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXT04198.1 - 0.0014 17.9 0.0 0.033 13.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXT04198.1 - 0.002 18.1 0.5 0.31 11.0 0.2 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KXT04198.1 - 0.0023 17.2 0.1 0.012 14.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXT04198.1 - 0.0036 16.4 0.1 0.011 14.9 0.1 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KXT04198.1 - 0.013 14.6 0.0 0.042 12.9 0.0 1.8 1 1 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 KXT04198.1 - 0.037 13.2 0.0 0.076 12.3 0.0 1.4 1 0 0 1 1 1 0 Thi4 family K_oxygenase PF13434.6 KXT04198.1 - 0.11 11.6 0.0 0.29 10.2 0.0 1.6 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) PLA2_B PF01735.18 KXT04199.1 - 1.1e-115 386.9 2.4 1.4e-115 386.5 2.4 1.2 1 0 0 1 1 1 1 Lysophospholipase catalytic domain IBR PF01485.21 KXT04200.1 - 3.6e-12 46.3 45.6 4.4e-08 33.2 8.9 4.3 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain Sedlin_N PF04628.13 KXT04201.1 - 5.8e-14 52.3 0.0 9.3e-14 51.7 0.0 1.3 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Formyl_trans_N PF00551.19 KXT04203.1 - 2.7e-25 89.2 0.0 4.1e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Peroxidase_2 PF01328.17 KXT04204.1 - 8.6e-41 140.5 0.1 1.6e-40 139.7 0.0 1.4 2 0 0 2 2 2 1 Peroxidase, family 2 Aldolase_II PF00596.21 KXT04205.1 - 1.4e-47 162.1 0.4 1.7e-47 161.8 0.4 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain AmpE PF17113.5 KXT04206.1 - 0.06 12.7 0.2 0.063 12.6 0.2 1.0 1 0 0 1 1 1 0 Regulatory signalling modulator protein AmpE GST_N_2 PF13409.6 KXT04208.1 - 3.4e-21 75.3 0.0 6.1e-21 74.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXT04208.1 - 1e-15 57.5 0.1 2.6e-15 56.2 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXT04208.1 - 6e-06 26.4 0.0 1.2e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXT04208.1 - 0.00017 21.7 0.1 0.00044 20.4 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KXT04208.1 - 0.018 15.4 0.0 7.4 7.1 0.0 2.3 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain DNMT1-RFD PF12047.8 KXT04208.1 - 0.067 13.2 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Cytosine specific DNA methyltransferase replication foci domain DUF3599 PF12206.8 KXT04208.1 - 0.069 13.5 0.0 0.75 10.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3599) Pkinase PF00069.25 KXT04209.1 - 2.1e-08 33.9 0.0 3.2e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT04209.1 - 8.5e-08 31.8 0.0 1.3e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Cnd1 PF12717.7 KXT04209.1 - 3.3e-07 30.5 0.1 3.4e-05 23.9 0.0 2.4 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KXT04209.1 - 2e-06 27.6 2.4 0.047 13.9 0.0 5.0 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 KXT04209.1 - 0.0004 20.8 0.3 1.4 9.5 0.1 3.7 4 0 0 4 4 4 2 HEAT-like repeat HEAT_2 PF13646.6 KXT04209.1 - 0.00076 19.8 2.1 0.019 15.4 0.2 2.8 2 1 1 3 3 3 2 HEAT repeats Kinase-like PF14531.6 KXT04209.1 - 0.084 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like SLC35F PF06027.12 KXT04210.1 - 3.4e-93 312.4 23.0 4.1e-93 312.2 23.0 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 KXT04210.1 - 4e-10 39.2 4.7 6.4e-10 38.5 4.7 1.3 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like HCV_env PF01539.17 KXT04210.1 - 0.026 14.2 5.4 0.05 13.3 5.4 1.4 1 0 0 1 1 1 0 Hepatitis C virus envelope glycoprotein E1 FUSC-like PF12805.7 KXT04210.1 - 1 8.3 7.9 2.1 7.3 2.4 3.3 2 1 1 3 3 3 0 FUSC-like inner membrane protein yccS Tim17 PF02466.19 KXT04210.1 - 2.6 8.5 6.6 3.1 8.2 2.4 2.8 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family EamA PF00892.20 KXT04210.1 - 9.7 6.4 36.0 2.6 8.2 15.2 2.4 2 0 0 2 2 2 0 EamA-like transporter family AA_permease PF00324.21 KXT04211.1 - 8.5e-96 321.4 42.5 1.1e-95 321.1 42.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXT04211.1 - 2.5e-21 76.0 46.1 3.3e-21 75.6 46.1 1.2 1 0 0 1 1 1 1 Amino acid permease Ammonium_transp PF00909.21 KXT04213.1 - 1.6e-63 214.8 24.0 2e-63 214.5 24.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family 4F5 PF04419.14 KXT04214.1 - 1.9e-08 35.0 14.5 1.9e-08 35.0 14.5 2.3 1 1 1 2 2 2 1 4F5 protein family DUF4578 PF15147.6 KXT04216.1 - 0.025 15.5 0.6 0.051 14.5 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4578) DUF3659 PF12396.8 KXT04217.1 - 3e-18 65.5 4.2 4.9e-18 64.8 4.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3659) DUF1899 PF08953.11 KXT04218.1 - 2.1e-36 123.6 0.0 4.1e-36 122.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 KXT04218.1 - 4.9e-20 71.1 0.2 1.2e-19 69.9 0.2 1.7 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 KXT04218.1 - 9.5e-17 61.1 6.1 0.0001 23.0 0.2 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXT04218.1 - 2e-06 28.0 0.1 0.016 15.5 0.0 3.6 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXT04218.1 - 0.00033 19.5 0.1 0.22 10.1 0.1 2.4 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KXT04218.1 - 0.00034 19.7 0.0 0.054 12.5 0.0 2.2 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein SSFA2_C PF14723.6 KXT04218.1 - 0.0092 15.9 0.3 0.018 14.9 0.3 1.6 1 0 0 1 1 1 1 Sperm-specific antigen 2 C-terminus DUF155 PF02582.14 KXT04219.1 - 3.3e-54 183.6 2.7 5e-54 183.1 2.7 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 zf-Tim10_DDP PF02953.15 KXT04220.1 - 7.2e-23 80.0 0.4 9.4e-23 79.6 0.4 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger UPF0253 PF06786.12 KXT04220.1 - 0.12 12.6 0.3 0.25 11.6 0.3 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0253) DUF1682 PF07946.14 KXT04221.1 - 6.8e-107 357.4 6.2 9.6e-107 356.9 6.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) adh_short PF00106.25 KXT04221.1 - 1.6e-91 305.1 11.8 1.8e-48 164.6 4.3 3.2 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXT04221.1 - 1.5e-71 240.6 9.1 1.4e-39 136.1 3.9 2.6 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT04221.1 - 9.2e-34 116.9 5.2 6.3e-19 68.6 1.5 2.5 2 0 0 2 2 2 2 KR domain MaoC_dehydratas PF01575.19 KXT04221.1 - 7.5e-27 93.3 0.0 1.6e-26 92.3 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KXT04221.1 - 1.1e-09 38.5 0.0 6.3e-07 29.6 0.0 3.2 3 0 0 3 3 3 1 N-terminal half of MaoC dehydratase Epimerase PF01370.21 KXT04221.1 - 0.00062 19.3 2.9 0.0022 17.5 0.8 2.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PYC_OADA PF02436.18 KXT04221.1 - 0.37 10.5 4.3 4.9 6.8 2.6 2.5 2 0 0 2 2 2 0 Conserved carboxylase domain DUF543 PF04418.12 KXT04221.1 - 1.4 9.0 5.5 3.5 7.7 0.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF543) Ribonuc_L-PSP PF01042.21 KXT04222.1 - 1.2e-37 128.6 0.0 1.5e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP BPL_LplA_LipB PF03099.19 KXT04223.1 - 0.089 12.7 0.0 0.34 10.8 0.0 1.8 1 1 0 1 1 1 0 Biotin/lipoate A/B protein ligase family Oxidored_q6 PF01058.22 KXT04224.1 - 4.6e-22 78.2 0.0 7.2e-22 77.6 0.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit adh_short_C2 PF13561.6 KXT04225.1 - 9.8e-53 179.1 0.0 1.2e-52 178.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXT04225.1 - 6.2e-38 130.2 0.0 8.2e-38 129.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXT04225.1 - 8.5e-08 32.3 0.0 1.2e-07 31.8 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KXT04225.1 - 0.0047 16.3 0.0 0.0056 16.1 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) TFIIE_alpha PF02002.17 KXT04226.1 - 2.7e-15 56.1 0.6 1.1e-14 54.1 0.0 2.3 2 1 0 2 2 2 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.12 KXT04226.1 - 0.001 18.5 2.1 0.0015 18.0 0.9 2.0 2 0 0 2 2 2 1 TFIIB zinc-binding HTH_24 PF13412.6 KXT04226.1 - 0.041 13.4 0.1 0.083 12.5 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding BUD22 PF09073.10 KXT04226.1 - 0.8 9.0 30.0 1.3 8.3 30.0 1.3 1 0 0 1 1 1 0 BUD22 DBC1 PF14443.6 KXT04227.1 - 0.017 15.1 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 DBC1 DBC1 PF14443.6 KXT04228.1 - 0.014 15.4 0.0 0.033 14.2 0.0 1.6 1 0 0 1 1 1 0 DBC1 GRAB PF10375.9 KXT04229.1 - 1.4e-09 37.5 0.1 2.8e-09 36.5 0.1 1.5 1 0 0 1 1 1 1 GRIP-related Arf-binding domain EzrA PF06160.12 KXT04229.1 - 0.075 11.2 47.7 0.21 9.8 14.5 3.1 1 1 2 3 3 3 0 Septation ring formation regulator, EzrA Filament PF00038.21 KXT04229.1 - 0.11 12.1 62.3 1.5 8.3 46.3 2.7 1 1 1 2 2 2 0 Intermediate filament protein DUF2353 PF09789.9 KXT04229.1 - 0.11 11.8 57.1 0.021 14.2 14.1 3.3 1 1 2 3 3 3 0 Uncharacterized coiled-coil protein (DUF2353) DUF2555 PF10742.9 KXT04229.1 - 0.16 11.8 0.8 0.65 9.9 0.8 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2555) Phage_GP20 PF06810.11 KXT04229.1 - 0.17 11.7 47.4 0.12 12.2 7.9 4.4 1 1 3 4 4 4 0 Phage minor structural protein GP20 Spc7 PF08317.11 KXT04229.1 - 0.2 10.5 64.2 0.095 11.6 26.3 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF3584 PF12128.8 KXT04229.1 - 0.4 8.1 66.3 2.6 5.4 30.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Golgin_A5 PF09787.9 KXT04229.1 - 0.57 9.6 65.6 0.11 12.0 25.3 3.6 1 1 2 3 3 3 0 Golgin subfamily A member 5 AAA_13 PF13166.6 KXT04229.1 - 0.71 8.4 45.9 0.1 11.3 26.6 2.2 1 1 0 2 2 2 0 AAA domain APG6_N PF17675.1 KXT04229.1 - 0.75 10.3 81.5 0.057 13.9 16.7 4.5 1 1 3 4 4 4 0 Apg6 coiled-coil region NPV_P10 PF05531.12 KXT04229.1 - 1.1 9.8 16.6 0.66 10.5 1.6 4.5 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 KXT04229.1 - 1.6 8.8 31.9 1.9 8.5 3.0 4.3 1 1 2 4 4 4 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 KXT04229.1 - 3.1 7.8 68.7 0.47 10.5 29.1 3.6 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4806 PF16064.5 KXT04229.1 - 4.8 7.6 5.3 2.9 8.3 0.6 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4806) Rootletin PF15035.6 KXT04229.1 - 4.9 7.1 65.2 0.15 12.1 10.9 3.5 2 1 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion FAD_binding_3 PF01494.19 KXT04239.1 - 1.6e-71 241.4 0.0 2.8e-71 240.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KXT04239.1 - 1.2e-39 136.1 0.0 2.3e-39 135.1 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Thi4 PF01946.17 KXT04239.1 - 0.013 14.7 0.0 0.022 14.0 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 KXT04239.1 - 0.022 13.8 0.0 0.035 13.2 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KXT04239.1 - 0.047 12.9 0.1 0.67 9.1 0.0 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Rhomboid PF01694.22 KXT04240.1 - 1.7e-23 83.3 11.9 3e-23 82.5 11.9 1.3 1 0 0 1 1 1 1 Rhomboid family Mpv17_PMP22 PF04117.12 KXT04241.1 - 2.6e-23 82.0 0.2 5.3e-23 81.0 0.2 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family AAA_11 PF13086.6 KXT04242.1 - 9.7e-61 205.8 0.3 9.7e-61 205.8 0.3 2.0 2 0 0 2 2 1 1 AAA domain AAA_12 PF13087.6 KXT04242.1 - 3.8e-57 193.1 0.0 2.8e-56 190.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KXT04242.1 - 1.6e-13 50.8 0.1 1.5e-11 44.4 0.1 3.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KXT04242.1 - 2.6e-10 40.8 0.2 3.9e-09 37.0 0.0 3.0 3 1 0 3 3 2 1 AAA domain UvrD-helicase PF00580.21 KXT04242.1 - 4e-08 33.1 0.2 9.7e-08 31.9 0.1 1.7 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 KXT04242.1 - 5.9e-08 32.4 2.8 8.6e-07 28.5 2.8 2.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 KXT04242.1 - 9e-08 32.1 0.1 0.071 12.8 0.0 3.6 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 KXT04242.1 - 1.2e-05 24.9 0.0 0.0084 15.6 0.0 2.7 2 1 1 3 3 3 1 PhoH-like protein ResIII PF04851.15 KXT04242.1 - 1.5e-05 25.1 0.0 7.2e-05 22.9 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD_C PF13361.6 KXT04242.1 - 1.9e-05 24.3 0.1 0.089 12.1 0.0 3.1 2 1 1 3 3 3 2 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 KXT04242.1 - 0.00014 22.1 0.2 0.0013 19.0 0.2 2.5 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 KXT04242.1 - 0.00041 20.2 0.2 0.0034 17.2 0.2 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_16 PF13191.6 KXT04242.1 - 0.00042 20.7 0.1 0.0039 17.6 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain T2SSE PF00437.20 KXT04242.1 - 0.00094 18.3 0.0 0.0023 17.0 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein Helicase_RecD PF05127.14 KXT04242.1 - 0.0015 18.4 0.1 0.17 11.8 0.0 3.5 2 2 0 2 2 2 1 Helicase Flavi_DEAD PF07652.14 KXT04242.1 - 0.0056 16.7 0.0 0.042 13.8 0.0 2.4 2 0 0 2 2 2 1 Flavivirus DEAD domain AAA_5 PF07728.14 KXT04242.1 - 0.0056 16.7 0.1 0.026 14.5 0.0 2.2 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 KXT04242.1 - 0.0059 17.0 0.4 0.028 14.9 0.1 2.5 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KXT04242.1 - 0.0069 15.8 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI PIF1 PF05970.14 KXT04242.1 - 0.013 14.7 0.0 3.9 6.5 0.0 2.4 2 0 0 2 2 2 0 PIF1-like helicase AAA_33 PF13671.6 KXT04242.1 - 0.016 15.3 0.1 0.06 13.5 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.6 KXT04242.1 - 0.018 14.6 0.2 0.33 10.5 0.0 2.7 2 1 1 3 3 3 0 AAA domain RuvB_N PF05496.12 KXT04242.1 - 0.022 14.5 0.5 0.086 12.6 0.0 2.2 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain UvrD_C_2 PF13538.6 KXT04242.1 - 0.027 14.3 0.0 0.13 12.1 0.0 2.2 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain IstB_IS21 PF01695.17 KXT04242.1 - 0.031 14.0 0.0 0.083 12.6 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein SKI PF01202.22 KXT04242.1 - 0.034 14.3 0.1 0.17 12.0 0.1 2.2 2 0 0 2 2 2 0 Shikimate kinase NACHT PF05729.12 KXT04242.1 - 0.035 14.0 0.2 0.59 10.0 0.0 2.7 3 0 0 3 3 2 0 NACHT domain 4HB_MCP_1 PF12729.7 KXT04242.1 - 0.04 13.5 0.2 0.092 12.3 0.2 1.6 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction AAA_24 PF13479.6 KXT04242.1 - 0.042 13.6 0.7 0.33 10.6 0.1 2.7 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KXT04242.1 - 0.062 12.6 0.4 0.42 9.9 0.4 2.2 1 1 0 1 1 1 0 FtsK/SpoIIIE family ABC_tran PF00005.27 KXT04242.1 - 0.069 13.7 0.2 0.43 11.1 0.0 2.6 2 1 0 2 2 1 0 ABC transporter AAA_7 PF12775.7 KXT04242.1 - 0.072 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 KXT04242.1 - 0.085 12.8 0.2 0.94 9.4 0.0 2.6 2 0 0 2 2 2 0 NTPase Hydin_ADK PF17213.3 KXT04242.1 - 0.13 12.6 4.3 5.1 7.3 0.1 3.1 3 0 0 3 3 2 0 Hydin Adenylate kinase-like domain AAA_23 PF13476.6 KXT04242.1 - 0.41 11.1 3.1 0.43 11.1 0.4 2.6 2 1 0 2 2 1 0 AAA domain SelR PF01641.18 KXT04243.1 - 1.6e-50 170.2 0.3 2e-50 169.9 0.3 1.1 1 0 0 1 1 1 1 SelR domain zinc_ribbon_10 PF10058.9 KXT04243.1 - 0.0069 16.1 0.1 0.35 10.6 0.0 2.3 2 0 0 2 2 2 1 Predicted integral membrane zinc-ribbon metal-binding protein Importin_rep PF18773.1 KXT04243.1 - 0.043 13.5 0.1 0.068 12.9 0.1 1.3 1 0 0 1 1 1 0 Importin 13 repeat GFA PF04828.14 KXT04243.1 - 0.048 14.0 0.8 2.2 8.7 0.1 2.3 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Yippee-Mis18 PF03226.14 KXT04243.1 - 0.063 13.5 0.2 0.14 12.4 0.2 1.6 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly TF_Zn_Ribbon PF08271.12 KXT04243.1 - 0.1 12.2 1.4 0.5 9.9 0.2 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding DZR PF12773.7 KXT04243.1 - 0.14 12.2 4.2 1.3 9.1 4.2 2.2 1 1 1 2 2 2 0 Double zinc ribbon MCM_OB PF17207.3 KXT04243.1 - 0.17 11.7 0.1 0.36 10.7 0.0 1.6 2 0 0 2 2 2 0 MCM OB domain ADH_N PF08240.12 KXT04245.1 - 2.5e-26 91.7 3.7 2.5e-26 91.7 3.7 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXT04245.1 - 1.9e-20 73.1 0.6 4.7e-20 71.9 0.6 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KXT04245.1 - 0.00026 20.4 0.8 0.00046 19.5 0.8 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Sacchrp_dh_NADP PF03435.18 KXT04245.1 - 0.00031 21.0 0.1 0.0006 20.1 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain IGFBP PF00219.18 KXT04245.1 - 0.012 16.2 0.5 0.051 14.2 0.5 2.0 1 0 0 1 1 1 0 Insulin-like growth factor binding protein UDPG_MGDP_dh_N PF03721.14 KXT04245.1 - 0.014 15.0 0.1 0.025 14.1 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ADH_zinc_N_2 PF13602.6 KXT04245.1 - 0.068 14.2 0.0 0.15 13.1 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase FKBP_C PF00254.28 KXT04245.1 - 0.11 12.9 0.2 4 7.8 0.0 2.6 2 0 0 2 2 2 0 FKBP-type peptidyl-prolyl cis-trans isomerase Sigma70_r4_2 PF08281.12 KXT04246.1 - 0.038 13.7 0.0 0.065 12.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 ADH_N PF08240.12 KXT04248.1 - 9.9e-32 109.1 0.6 1.7e-31 108.3 0.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXT04248.1 - 4.9e-23 81.5 2.5 7e-23 81.0 0.8 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXT04248.1 - 5.3e-10 40.5 0.1 1.1e-09 39.4 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 KXT04248.1 - 0.038 14.3 0.3 0.072 13.4 0.3 1.6 1 0 0 1 1 1 0 TrkA-N domain Methyltransf_31 PF13847.6 KXT04248.1 - 0.046 13.5 0.1 0.086 12.6 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain 3HCDH_N PF02737.18 KXT04248.1 - 0.07 13.0 0.6 0.11 12.3 0.6 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF4911 PF16256.5 KXT04248.1 - 0.093 12.7 0.1 0.2 11.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4911) MTS PF05175.14 KXT04248.1 - 0.14 11.7 0.2 0.33 10.5 0.1 1.5 1 1 0 1 1 1 0 Methyltransferase small domain DMAP1 PF05499.12 KXT04248.1 - 0.22 11.4 0.0 0.38 10.6 0.0 1.3 1 0 0 1 1 1 0 DNA methyltransferase 1-associated protein 1 (DMAP1) POP1 PF06978.11 KXT04249.1 - 3e-71 239.6 15.3 3e-71 239.6 15.3 1.9 2 0 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 KXT04249.1 - 8.1e-31 106.2 0.7 8.1e-31 106.2 0.7 2.6 2 0 0 2 2 2 1 POPLD (NUC188) domain IBR PF01485.21 KXT04250.1 - 1.2e-07 31.8 53.1 0.00013 22.1 15.6 4.4 4 0 0 4 4 4 3 IBR domain, a half RING-finger domain zf-RING_5 PF14634.6 KXT04250.1 - 0.011 15.7 5.8 0.011 15.7 5.8 4.8 4 1 0 4 4 4 0 zinc-RING finger domain DUF1689 PF07954.11 KXT04251.1 - 0.0032 17.9 0.1 0.0039 17.6 0.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1689) Hjc PF01870.18 KXT04251.1 - 0.037 14.0 0.0 0.061 13.3 0.0 1.4 1 0 0 1 1 1 0 Archaeal holliday junction resolvase (hjc) Tim17 PF02466.19 KXT04251.1 - 0.067 13.6 0.7 4.4 7.7 0.0 2.2 2 0 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Malate_DH PF12434.8 KXT04251.1 - 3 8.0 5.7 0.67 10.0 0.4 2.2 2 0 0 2 2 2 0 Malate dehydrogenase enzyme XPG_N PF00752.17 KXT04252.1 - 4.9e-36 123.3 0.0 1.2e-35 122.0 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KXT04252.1 - 2e-25 88.9 1.1 3.7e-25 88.1 0.0 2.1 2 0 0 2 2 2 1 XPG I-region UIM PF02809.20 KXT04252.1 - 0.001 18.8 3.8 0.001 18.8 3.8 3.8 3 0 0 3 3 3 1 Ubiquitin interaction motif 5_3_exonuc PF01367.20 KXT04252.1 - 0.013 16.1 0.0 0.04 14.5 0.0 1.9 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold SAUGI PF06106.11 KXT04253.1 - 0.7 10.4 3.4 0.85 10.2 0.1 2.4 3 0 0 3 3 3 0 S. aureus uracil DNA glycosylase inhibitor SAUGI PF06106.11 KXT04254.1 - 0.7 10.4 3.4 0.85 10.2 0.1 2.4 3 0 0 3 3 3 0 S. aureus uracil DNA glycosylase inhibitor SAUGI PF06106.11 KXT04255.1 - 0.7 10.4 3.4 0.85 10.2 0.1 2.4 3 0 0 3 3 3 0 S. aureus uracil DNA glycosylase inhibitor Fungal_trans_2 PF11951.8 KXT04256.1 - 2.7e-52 177.9 0.0 4.6e-52 177.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT04256.1 - 3.4e-06 27.1 8.2 6.1e-06 26.3 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF512 PF04459.12 KXT04256.1 - 0.065 12.5 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF512) Fungal_trans_2 PF11951.8 KXT04257.1 - 2.7e-52 177.9 0.0 4.6e-52 177.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT04257.1 - 3.4e-06 27.1 8.2 6.1e-06 26.3 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF512 PF04459.12 KXT04257.1 - 0.065 12.5 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF512) Fungal_trans_2 PF11951.8 KXT04258.1 - 3e-52 177.7 0.0 5.3e-52 176.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT04258.1 - 3.6e-06 27.0 8.2 6.5e-06 26.2 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF512 PF04459.12 KXT04258.1 - 0.07 12.4 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF512) fn3_2 PF16893.5 KXT04261.1 - 3e-36 123.4 0.0 5.1e-36 122.7 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 KXT04261.1 - 5.6e-24 83.8 0.3 1.1e-23 82.9 0.3 1.5 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus PTCB-BRCT PF12738.7 KXT04261.1 - 3.3e-14 52.6 0.0 5.9e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 KXT04261.1 - 1e-07 32.2 0.0 1.8e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3006 PF11213.8 KXT04261.1 - 7.9e-06 26.0 0.0 3.4e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3006) fn3 PF00041.21 KXT04261.1 - 9.3e-05 22.7 0.0 0.00027 21.2 0.0 1.8 1 1 0 1 1 1 1 Fibronectin type III domain BRCT_2 PF16589.5 KXT04261.1 - 0.0011 19.4 0.0 0.0021 18.4 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain VIR_N PF15912.5 KXT04261.1 - 1.9 8.0 17.4 2.9 7.4 17.4 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal EutQ PF06249.12 KXT04262.1 - 1.2e-06 28.4 0.0 1.9e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_2 PF07883.11 KXT04262.1 - 0.00011 21.8 0.0 0.00025 20.7 0.0 1.6 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 KXT04262.1 - 0.00031 20.4 0.0 0.00057 19.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_1 PF00190.22 KXT04262.1 - 0.07 12.7 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Cupin Rad10 PF03834.14 KXT04263.1 - 2.2e-45 153.4 0.2 3.6e-45 152.6 0.2 1.4 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 KXT04263.1 - 0.028 15.0 0.0 0.054 14.1 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix domain KRBA1 PF15287.6 KXT04264.1 - 0.38 10.5 3.0 0.72 9.6 1.3 2.3 2 0 0 2 2 2 0 KRBA1 family repeat DNA_pol_B_palm PF14792.6 KXT04265.1 - 3.9e-32 110.9 0.0 8.3e-32 109.8 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.6 KXT04265.1 - 8.8e-19 67.7 0.2 2.9e-18 66.0 0.2 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 KXT04265.1 - 1.4e-18 66.4 0.1 3.7e-18 65.1 0.1 1.8 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.6 KXT04265.1 - 1.3e-11 44.4 0.0 3.7e-11 43.0 0.0 1.8 1 0 0 1 1 1 1 DNA polymerase beta thumb IBR PF01485.21 KXT04265.1 - 9.5e-08 32.2 6.7 9.5e-08 32.2 6.7 2.9 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain BRCT_2 PF16589.5 KXT04265.1 - 0.00025 21.4 0.0 0.00064 20.1 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KXT04265.1 - 0.00058 20.2 0.0 0.0027 18.0 0.0 2.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain NTP_transf_2 PF01909.23 KXT04265.1 - 0.016 15.5 0.0 0.049 13.9 0.0 1.8 1 0 0 1 1 1 0 Nucleotidyltransferase domain 5_3_exonuc PF01367.20 KXT04265.1 - 0.063 13.9 0.0 0.29 11.7 0.0 2.1 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold DSPc PF00782.20 KXT04266.1 - 5.6e-25 87.7 0.0 2.1e-24 85.8 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KXT04266.1 - 0.073 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase HCO3_cotransp PF00955.21 KXT04267.1 - 1.6e-71 241.7 6.9 6.4e-42 144.0 3.6 2.6 1 1 1 2 2 2 2 HCO3- transporter family MFS_1 PF07690.16 KXT04268.1 - 2.9e-41 141.6 29.1 2.9e-41 141.6 29.1 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXT04268.1 - 2.8e-12 46.3 15.0 2.8e-12 46.3 15.0 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KXT04268.1 - 5e-12 45.0 5.0 7.8e-12 44.4 5.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) COesterase PF00135.28 KXT04269.1 - 7.4e-58 196.7 0.0 1.1e-57 196.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family ATP-synt_E PF05680.12 KXT04269.1 - 1.2e-16 60.8 0.1 2.6e-16 59.8 0.1 1.5 1 0 0 1 1 1 1 ATP synthase E chain Abhydrolase_3 PF07859.13 KXT04269.1 - 2.9e-10 40.4 0.4 2.4e-09 37.4 0.1 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXT04269.1 - 0.0022 18.6 0.2 0.0067 17.0 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KXT04269.1 - 0.011 15.2 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family PT PF04886.12 KXT04270.1 - 2.1 8.0 15.5 0.021 14.4 5.0 2.8 3 0 0 3 3 3 0 PT repeat Bac_rhodopsin PF01036.18 KXT04271.1 - 1.5e-48 165.3 18.2 1.8e-48 165.0 18.2 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Heliorhodopsin PF18761.1 KXT04271.1 - 0.00021 20.7 9.8 0.00042 19.7 9.8 1.6 1 1 0 1 1 1 1 Heliorhodopsin DUF3810 PF12725.7 KXT04271.1 - 0.33 10.3 5.8 1.2 8.4 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) DUF2516 PF10724.9 KXT04271.1 - 0.7 10.2 8.3 1.6 9.1 3.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2516) MerC PF03203.14 KXT04271.1 - 0.76 10.3 14.7 1 9.8 7.7 2.4 2 0 0 2 2 2 0 MerC mercury resistance protein DUF1772 PF08592.11 KXT04271.1 - 4.8 7.5 13.2 3.3 8.0 1.2 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) RPEL PF02755.15 KXT04272.1 - 8.9e-08 31.6 2.8 8.9e-08 31.6 2.8 2.2 2 0 0 2 2 2 1 RPEL repeat RPEL PF02755.15 KXT04273.1 - 2.8e-14 52.3 2.5 8.7e-07 28.4 0.0 2.4 3 0 0 3 3 3 2 RPEL repeat NT-C2 PF10358.9 KXT04274.1 - 1.8e-31 108.8 0.0 3.2e-31 108.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins PrpF PF04303.13 KXT04275.1 - 7.6e-22 77.8 0.0 1.1e-21 77.3 0.0 1.1 1 0 0 1 1 1 1 PrpF protein Pro_racemase PF05544.11 KXT04275.1 - 0.059 12.4 0.0 0.084 11.9 0.0 1.1 1 0 0 1 1 1 0 Proline racemase DUF5127 PF17168.4 KXT04276.1 - 4.6e-78 262.1 11.7 4.3e-45 154.2 6.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KXT04276.1 - 7.1e-75 250.5 2.0 7.2e-75 250.4 0.4 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KXT04276.1 - 2.5e-65 220.0 1.3 2.5e-65 220.0 1.3 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KXT04276.1 - 1.8e-07 30.6 0.1 6.9e-07 28.7 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4964) MS_channel PF00924.18 KXT04278.1 - 6.1e-13 48.8 1.5 1.6e-12 47.5 0.4 2.0 2 0 0 2 2 2 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 KXT04278.1 - 0.00079 18.8 1.1 0.0034 16.8 0.6 2.2 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KXT04278.1 - 0.0012 18.6 0.2 0.017 15.0 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 KXT04278.1 - 0.0063 16.9 0.1 0.029 14.8 0.1 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 KXT04278.1 - 0.027 14.0 0.4 0.52 9.9 0.4 2.5 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.6 KXT04278.1 - 0.12 12.2 0.9 0.31 10.9 0.3 2.0 2 0 0 2 2 2 0 EF-hand domain pair DUF2976 PF11190.8 KXT04278.1 - 0.67 9.8 3.9 0.72 9.7 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) DUF3810 PF12725.7 KXT04278.1 - 0.68 9.2 8.9 5.8 6.2 3.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3810) DUF1793 PF08760.11 KXT04280.1 - 1.2e-69 234.0 0.2 5.2e-69 231.9 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4965 PF16335.5 KXT04280.1 - 1e-61 207.6 0.2 5.5e-49 166.1 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4965) DUF5127 PF17168.4 KXT04280.1 - 1e-41 143.2 3.5 1.6e-41 142.5 3.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4964 PF16334.5 KXT04280.1 - 0.0033 17.0 0.1 0.008 15.7 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) Ndufs5 PF10200.9 KXT04281.1 - 0.0004 20.6 0.1 0.00062 20.0 0.1 1.3 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.8 KXT04281.1 - 0.0022 18.3 0.6 0.0042 17.4 0.6 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3128) UPF0203 PF05254.12 KXT04281.1 - 0.027 14.7 0.7 0.047 13.9 0.7 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0203) COX17 PF05051.13 KXT04281.1 - 0.063 13.6 0.4 0.11 12.8 0.4 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) AMP-binding PF00501.28 KXT04283.1 - 2.8e-67 227.2 0.0 6e-67 226.1 0.0 1.6 1 1 1 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXT04283.1 - 7.4e-12 46.1 0.0 1.6e-11 45.0 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PHD PF00628.29 KXT04284.1 - 7.6e-07 28.9 8.9 1.6e-06 27.9 8.9 1.6 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KXT04284.1 - 0.082 13.2 3.1 0.19 12.0 3.1 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.6 KXT04284.1 - 0.12 11.9 2.8 0.23 11.1 2.8 1.5 1 0 0 1 1 1 0 PHD-finger Piwi PF02171.17 KXT04285.1 - 8.6e-59 199.2 0.0 1.3e-58 198.6 0.0 1.3 1 0 0 1 1 1 1 Piwi domain Oxidored_FMN PF00724.20 KXT04285.1 - 1.9e-36 126.0 0.0 2.9e-36 125.4 0.0 1.3 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family ArgoL1 PF08699.10 KXT04285.1 - 2.3e-08 33.6 0.1 5.9e-08 32.3 0.1 1.8 1 0 0 1 1 1 1 Argonaute linker 1 domain zf-C2H2 PF00096.26 KXT04286.1 - 1.3e-11 44.2 10.3 2e-05 24.8 0.5 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXT04286.1 - 4.4e-09 36.4 8.5 0.00043 20.9 0.5 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXT04286.1 - 8.3e-07 29.2 10.9 3.5e-05 24.0 1.7 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KXT04286.1 - 0.00029 21.0 1.5 0.036 14.4 0.0 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KXT04286.1 - 0.00035 20.3 5.7 0.086 12.6 0.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KXT04286.1 - 0.028 14.4 4.4 1.4 9.0 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KXT04286.1 - 0.18 11.6 2.3 10 6.0 0.2 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-met PF12874.7 KXT04286.1 - 0.19 12.2 2.6 0.62 10.5 0.1 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HE PF16278.5 KXT04286.1 - 0.3 11.6 7.0 2 8.9 1.2 2.3 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2 PF00096.26 KXT04287.1 - 1.3e-11 44.2 10.3 2e-05 24.8 0.5 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXT04287.1 - 4.4e-09 36.4 8.5 0.00043 20.9 0.5 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXT04287.1 - 8.3e-07 29.2 10.9 3.5e-05 24.0 1.7 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KXT04287.1 - 0.00029 21.0 1.5 0.036 14.4 0.0 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KXT04287.1 - 0.00035 20.3 5.7 0.086 12.6 0.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KXT04287.1 - 0.028 14.4 4.4 1.4 9.0 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KXT04287.1 - 0.18 11.6 2.3 10 6.0 0.2 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-met PF12874.7 KXT04287.1 - 0.19 12.2 2.6 0.62 10.5 0.1 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HE PF16278.5 KXT04287.1 - 0.3 11.6 7.0 2 8.9 1.2 2.3 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Rad51 PF08423.11 KXT04289.1 - 0.0001 21.7 0.2 0.0044 16.3 0.2 2.1 1 1 0 1 1 1 1 Rad51 CSM2 PF16834.5 KXT04289.1 - 0.0073 16.0 0.5 0.011 15.4 0.0 1.5 2 0 0 2 2 2 1 Shu complex component Csm2, DNA-binding Pex14_N PF04695.13 KXT04290.1 - 0.16 12.6 7.2 0.3 11.7 7.2 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Beta-lactamase PF00144.24 KXT04292.1 - 2.5e-43 148.6 0.1 4.5e-43 147.8 0.1 1.3 1 1 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 KXT04292.1 - 0.19 11.3 0.0 0.67 9.5 0.0 1.8 2 0 0 2 2 2 0 Beta-lactamase enzyme family His_Phos_2 PF00328.22 KXT04293.1 - 4.6e-65 220.4 0.0 6.1e-65 220.0 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Ribosomal_L7Ae PF01248.26 KXT04294.1 - 1.1e-24 85.9 0.0 1.4e-24 85.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KXT04294.1 - 0.0026 17.9 0.0 0.0028 17.7 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 KXT04294.1 - 0.0028 17.5 0.0 0.0037 17.1 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain FAA_hydrolase PF01557.18 KXT04295.1 - 1.1e-62 211.5 0.0 2.7e-62 210.3 0.0 1.7 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Abhydrolase_1 PF00561.20 KXT04295.1 - 5.3e-23 82.0 0.1 3e-22 79.5 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Amidohydro_1 PF01979.20 KXT04295.1 - 5.1e-20 72.1 1.0 7.6e-20 71.5 1.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family Hydrolase_4 PF12146.8 KXT04295.1 - 5.6e-18 65.1 0.0 1.2e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXT04295.1 - 7.5e-18 65.9 0.0 1.5e-17 65.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Amidohydro_3 PF07969.11 KXT04295.1 - 3.7e-09 36.6 5.0 1.8e-05 24.4 0.7 4.0 1 1 1 2 2 2 2 Amidohydrolase family Ser_hydrolase PF06821.13 KXT04295.1 - 8.7e-06 25.7 0.1 0.0034 17.3 0.0 2.3 2 0 0 2 2 2 2 Serine hydrolase LIDHydrolase PF10230.9 KXT04295.1 - 0.00019 21.1 0.0 0.0023 17.6 0.0 2.1 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase Abhydrolase_8 PF06259.12 KXT04295.1 - 0.0019 17.8 0.0 0.0041 16.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase Ndr PF03096.14 KXT04295.1 - 0.0042 15.8 0.0 0.0098 14.6 0.0 1.5 1 1 0 1 1 1 1 Ndr family Abhydrolase_4 PF08386.10 KXT04295.1 - 0.029 14.5 0.0 0.08 13.1 0.0 1.7 1 0 0 1 1 1 0 TAP-like protein DUF3860 PF12976.7 KXT04295.1 - 0.15 12.1 0.0 0.41 10.7 0.0 1.7 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3860) DnaJ-X PF14308.6 KXT04296.1 - 5.2e-77 258.0 2.7 5.2e-77 258.0 2.7 2.8 4 0 0 4 4 4 1 X-domain of DnaJ-containing DnaJ PF00226.31 KXT04296.1 - 1.1e-25 89.6 1.7 2.6e-25 88.3 1.7 1.7 1 0 0 1 1 1 1 DnaJ domain U1snRNP70_N PF12220.8 KXT04296.1 - 1.3 9.7 14.3 2.6 8.7 1.9 3.9 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Sld5 PF05916.11 KXT04297.1 - 3.2e-11 43.6 0.0 4.9e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein Kelch_4 PF13418.6 KXT04299.1 - 1.7e-16 60.0 1.7 8.9e-07 28.8 0.0 4.8 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.6 KXT04299.1 - 4.5e-16 58.7 4.9 5.7e-09 36.0 0.0 5.6 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 KXT04299.1 - 7.5e-14 51.3 0.6 4.5e-06 26.5 0.1 3.7 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.25 KXT04299.1 - 1.5e-13 50.1 0.4 0.0024 17.4 0.0 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 KXT04299.1 - 5.7e-11 42.3 0.2 0.001 19.3 0.0 4.9 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 KXT04299.1 - 5.6e-08 32.5 0.2 0.029 14.4 0.0 4.1 4 0 0 4 4 4 2 Kelch motif BTB PF00651.31 KXT04299.1 - 0.046 14.0 0.0 0.082 13.1 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain A_deaminase PF00962.22 KXT04300.1 - 9.9e-125 416.2 0.2 1.7e-124 415.4 0.2 1.4 1 0 0 1 1 1 1 Adenosine/AMP deaminase SF1-HH PF16275.5 KXT04301.1 - 1.9e-44 150.6 0.8 4.6e-44 149.4 0.8 1.6 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 KXT04301.1 - 5e-12 45.3 11.1 1.3e-05 25.1 0.8 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 KXT04301.1 - 2.7e-07 30.4 5.9 0.00014 21.8 3.2 2.6 1 1 1 2 2 2 2 Zinc knuckle KH_1 PF00013.29 KXT04301.1 - 7.1e-07 29.0 0.3 1.6e-06 27.9 0.3 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_6 PF15288.6 KXT04301.1 - 0.00018 21.3 6.7 0.09 12.6 0.3 2.9 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 KXT04301.1 - 0.00086 19.0 4.7 0.66 9.8 0.5 2.9 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_2 PF13696.6 KXT04301.1 - 0.015 15.1 0.7 0.015 15.1 0.7 2.3 2 0 0 2 2 2 0 Zinc knuckle Prim_Zn_Ribbon PF08273.12 KXT04301.1 - 6.5 7.1 7.7 0.77 10.1 2.6 2.0 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase SF1-HH PF16275.5 KXT04302.1 - 1.8e-44 150.7 0.8 4.2e-44 149.5 0.8 1.6 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 KXT04302.1 - 4.4e-12 45.5 11.1 1.2e-05 25.2 0.8 2.3 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.29 KXT04302.1 - 3.2e-08 33.3 0.1 6.4e-08 32.3 0.1 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.6 KXT04302.1 - 2.3e-07 30.6 5.9 0.00013 21.9 3.2 2.6 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 KXT04302.1 - 0.00015 21.5 6.7 0.085 12.7 0.3 2.9 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 KXT04302.1 - 0.00075 19.2 4.7 0.62 9.8 0.5 2.9 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_2 PF13696.6 KXT04302.1 - 0.014 15.2 0.7 0.014 15.2 0.7 2.4 2 0 0 2 2 2 0 Zinc knuckle Prim_Zn_Ribbon PF08273.12 KXT04302.1 - 5.8 7.3 7.7 0.73 10.2 2.6 2.1 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase HpcH_HpaI PF03328.14 KXT04303.1 - 7.4e-29 100.5 0.0 2.1e-28 99.0 0.0 1.8 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family WD40 PF00400.32 KXT04304.1 - 3.2e-06 27.8 9.0 0.014 16.3 0.4 5.5 6 1 0 6 6 6 3 WD domain, G-beta repeat Zn_clus PF00172.18 KXT04305.1 - 1.4e-07 31.5 10.7 2.4e-07 30.7 10.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KXT04306.1 - 3.8e-08 33.3 13.4 6.7e-08 32.5 13.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LXG PF04740.12 KXT04306.1 - 0.16 11.7 0.1 0.23 11.1 0.1 1.1 1 0 0 1 1 1 0 LXG domain of WXG superfamily Saw1 PF11561.8 KXT04308.1 - 0.19 11.3 9.1 0.86 9.1 5.8 2.5 1 1 0 2 2 2 0 Single strand annealing-weakened 1 CDC45 PF02724.14 KXT04308.1 - 0.41 8.9 4.1 0.48 8.7 4.1 1.2 1 0 0 1 1 1 0 CDC45-like protein UBA2_C PF16195.5 KXT04308.1 - 0.51 11.1 9.8 0.068 13.9 4.3 2.2 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus UQ_con PF00179.26 KXT04310.1 - 4.9e-27 94.3 0.0 1e-26 93.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Mut7-C PF01927.16 KXT04310.1 - 0.11 12.5 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Mut7-C RNAse domain Zn_clus PF00172.18 KXT04311.1 - 1e-08 35.2 7.7 1.5e-08 34.6 7.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 KXT04312.1 - 6.9e-66 222.3 0.0 1.6e-64 217.8 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Fungal_KA1 PF16797.5 KXT04312.1 - 2.9e-37 127.0 0.0 5.4e-37 126.1 0.0 1.5 1 0 0 1 1 1 1 Fungal kinase associated-1 domain Pkinase_Tyr PF07714.17 KXT04312.1 - 1.5e-31 109.7 0.0 5e-31 107.9 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Choline_kinase PF01633.20 KXT04312.1 - 0.0001 22.0 0.0 0.00027 20.6 0.0 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase Haspin_kinase PF12330.8 KXT04312.1 - 0.00016 20.8 0.0 0.00031 19.8 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KXT04312.1 - 0.0003 20.2 0.0 0.00078 18.9 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXT04312.1 - 0.00049 20.1 0.6 0.0016 18.4 0.0 2.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KXT04312.1 - 0.017 14.5 0.0 0.038 13.3 0.0 1.6 1 0 0 1 1 1 0 Kinase-like MSA-2c PF12238.8 KXT04312.1 - 6.1 6.8 7.5 26 4.7 7.5 2.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c UQ_con PF00179.26 KXT04313.1 - 5.6e-47 158.9 0.0 6.3e-47 158.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXT04313.1 - 2.6e-05 23.9 0.0 3.3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KXT04313.1 - 0.1 12.4 0.0 0.21 11.5 0.0 1.5 1 1 0 1 1 1 0 UEV domain ATP-synt_C PF00137.21 KXT04314.1 - 9.8e-36 121.9 33.8 5.5e-22 77.9 14.8 2.1 2 0 0 2 2 2 2 ATP synthase subunit C DUF2244 PF10003.9 KXT04314.1 - 1.5 8.5 5.0 0.19 11.4 0.5 1.8 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) Cyt-b5 PF00173.28 KXT04315.1 - 4.4e-14 52.4 0.0 7.2e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain BOP1NT PF08145.12 KXT04318.1 - 1e-101 340.2 5.4 1e-101 340.2 5.4 1.8 2 0 0 2 2 2 1 BOP1NT (NUC169) domain WD40 PF00400.32 KXT04318.1 - 1.3e-25 89.2 8.0 8.4e-10 39.1 0.1 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXT04318.1 - 2.4e-08 34.2 0.1 0.0058 16.9 0.0 3.8 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Rox3 PF08633.10 KXT04319.1 - 9.6e-58 195.8 1.4 1.5e-57 195.2 1.4 1.3 1 0 0 1 1 1 1 Rox3 mediator complex subunit Rox3 PF08633.10 KXT04320.1 - 8.7e-58 196.0 1.4 1.4e-57 195.3 1.4 1.3 1 0 0 1 1 1 1 Rox3 mediator complex subunit Syntaxin PF00804.25 KXT04321.1 - 5.3e-20 71.9 11.8 1.2e-19 70.8 10.6 2.2 1 1 0 1 1 1 1 Syntaxin SNARE PF05739.19 KXT04321.1 - 4.8e-15 55.3 0.6 1.4e-14 53.8 0.6 1.9 1 0 0 1 1 1 1 SNARE domain TMPIT PF07851.13 KXT04321.1 - 0.15 11.3 1.7 5.6 6.1 0.4 2.2 2 0 0 2 2 2 0 TMPIT-like protein Syntaxin_2 PF14523.6 KXT04321.1 - 0.42 11.0 10.8 0.24 11.8 3.0 3.0 2 1 0 2 2 2 0 Syntaxin-like protein DUF4094 PF13334.6 KXT04321.1 - 1.5 9.3 8.3 0.3 11.5 0.6 3.7 4 1 1 5 5 5 0 Domain of unknown function (DUF4094) BLOC1_2 PF10046.9 KXT04321.1 - 2.3 8.6 7.6 0.43 10.9 0.7 3.2 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3018 PF11455.8 KXT04321.1 - 3.6 7.6 5.8 26 4.8 1.5 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3018) HsbA PF12296.8 KXT04322.1 - 1.4e-27 96.4 12.7 1.4e-27 96.4 12.7 1.9 2 0 0 2 2 2 1 Hydrophobic surface binding protein A PIR PF00399.19 KXT04322.1 - 0.0046 16.5 4.0 0.0046 16.5 4.0 2.7 2 0 0 2 2 2 1 Yeast PIR protein repeat Fungal_trans_2 PF11951.8 KXT04323.1 - 3.2e-08 32.8 0.0 1.7e-06 27.1 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT04323.1 - 4.4e-08 33.1 9.3 9.1e-08 32.1 9.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXT04324.1 - 2.3e-08 33.3 0.0 1.4e-06 27.4 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT04324.1 - 4e-08 33.3 9.3 7.8e-08 32.3 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain eIF3m_C_helix PF18005.1 KXT04324.1 - 2.8 7.7 5.6 1.5 8.6 2.1 2.3 2 0 0 2 2 2 0 eIF3 subunit M, C-terminal helix Amidase PF01425.21 KXT04325.1 - 5.4e-98 328.9 0.0 7.7e-98 328.4 0.0 1.2 1 0 0 1 1 1 1 Amidase CBP4 PF07960.11 KXT04326.1 - 1.2e-27 96.3 0.7 1.3e-27 96.2 0.7 1.0 1 0 0 1 1 1 1 CBP4 BolA PF01722.18 KXT04327.1 - 3.6e-30 104.0 2.3 4.7e-30 103.7 2.3 1.1 1 0 0 1 1 1 1 BolA-like protein PhoLip_ATPase_C PF16212.5 KXT04328.1 - 4.9e-77 259.1 28.4 4.9e-77 259.1 28.4 2.1 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KXT04328.1 - 7.8e-18 63.9 0.5 2e-17 62.6 0.5 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KXT04328.1 - 5.2e-13 49.8 0.9 3.1e-09 37.4 0.7 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXT04328.1 - 2.5e-12 46.7 0.0 1.1e-11 44.6 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KXT04328.1 - 0.0014 18.2 0.9 0.0081 15.7 0.0 2.6 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KXT04328.1 - 0.01 15.6 0.2 0.025 14.3 0.2 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase NAPRTase PF04095.16 KXT04329.1 - 5.2e-55 186.7 0.5 1e-53 182.4 0.5 2.1 1 1 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 KXT04329.1 - 1.6e-36 125.4 0.1 2.5e-36 124.8 0.1 1.3 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain STT3_PglB_C PF18527.1 KXT04329.1 - 0.0083 16.2 0.2 0.03 14.4 0.1 2.0 2 0 0 2 2 2 1 STT3/PglB C-terminal beta-barrel domain GAF_2 PF13185.6 KXT04330.1 - 5.7e-10 39.6 0.0 1.2e-09 38.6 0.0 1.5 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 KXT04330.1 - 0.00018 22.2 0.0 0.00029 21.5 0.0 1.4 1 0 0 1 1 1 1 GAF domain rRNA_methylase PF06962.12 KXT04330.1 - 0.0037 17.2 0.0 0.0064 16.5 0.0 1.4 1 0 0 1 1 1 1 Putative rRNA methylase Peptidase_M20 PF01546.28 KXT04332.1 - 3e-25 89.1 0.0 2.1e-23 83.1 0.0 2.3 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.32 KXT04332.1 - 4.6e-14 52.6 1.0 9.3e-05 23.1 0.0 5.8 5 0 0 5 5 5 3 WD domain, G-beta repeat M20_dimer PF07687.14 KXT04332.1 - 1.9e-06 27.8 0.0 4.3e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain ANAPC4_WD40 PF12894.7 KXT04332.1 - 0.003 17.8 0.0 0.64 10.4 0.0 2.9 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KXT04332.1 - 0.089 12.1 0.0 3.5 6.9 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain PQQ_3 PF13570.6 KXT04332.1 - 8.9 7.0 9.0 1.1e+02 3.5 0.0 4.9 4 1 1 5 5 5 0 PQQ-like domain DnaJ PF00226.31 KXT04336.1 - 1.2e-20 73.3 0.8 3e-20 72.1 0.8 1.7 1 0 0 1 1 1 1 DnaJ domain AhpC-TSA PF00578.21 KXT04337.1 - 3.2e-30 104.6 0.0 4.2e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KXT04337.1 - 1e-12 48.0 0.0 1.3e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KXT04337.1 - 5.4e-10 38.9 0.1 1.1e-09 38.0 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin GST_C_3 PF14497.6 KXT04338.1 - 4.8e-30 103.7 0.7 9.4e-30 102.7 0.7 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXT04338.1 - 8.7e-09 35.5 0.2 1.8e-08 34.5 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXT04338.1 - 1.2e-05 25.2 0.1 2.4e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Sulfotransfer_4 PF17784.1 KXT04339.1 - 1.2e-66 224.6 0.0 1.5e-66 224.3 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KXT04339.1 - 0.0031 17.9 0.4 0.017 15.5 0.0 2.1 1 1 0 2 2 2 1 Sulfotransferase family CHORD PF04968.12 KXT04340.1 - 3.2e-48 162.3 23.4 3.6e-25 88.5 8.9 2.5 2 0 0 2 2 2 2 CHORD CS PF04969.16 KXT04340.1 - 8.4e-14 52.4 0.1 1.5e-13 51.5 0.1 1.4 1 0 0 1 1 1 1 CS domain BTK PF00779.19 KXT04340.1 - 0.46 10.4 8.0 3.8 7.4 1.0 3.0 2 0 0 2 2 2 0 BTK motif Acetyltransf_CG PF14542.6 KXT04341.1 - 4.7e-05 23.4 0.0 7.2e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.7 KXT04341.1 - 8.1e-05 22.6 0.0 0.0001 22.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXT04341.1 - 0.00029 21.1 0.0 0.00047 20.4 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KXT04341.1 - 0.0019 18.3 0.0 0.0027 17.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 KXT04341.1 - 0.046 13.9 0.0 0.075 13.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXT04341.1 - 0.06 13.8 0.0 0.091 13.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AAA_23 PF13476.6 KXT04342.1 - 1.9e-22 80.8 0.4 1.9e-22 80.8 0.4 5.2 2 2 1 3 3 3 1 AAA domain SMC_N PF02463.19 KXT04342.1 - 1.9e-21 76.5 0.0 3.4e-21 75.7 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KXT04342.1 - 8.9e-05 22.4 13.7 0.00082 19.2 0.0 3.3 2 2 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KXT04342.1 - 0.00032 20.6 7.8 0.014 15.2 0.0 3.3 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXT04342.1 - 0.0028 17.3 0.0 0.0077 16.0 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain Baculo_PEP_C PF04513.12 KXT04342.1 - 0.009 16.1 22.1 1 9.4 1.2 5.0 3 3 0 4 4 4 3 Baculovirus polyhedron envelope protein, PEP, C terminus Seryl_tRNA_N PF02403.22 KXT04342.1 - 0.012 15.9 11.1 0.012 15.9 11.1 7.1 3 2 4 7 7 7 0 Seryl-tRNA synthetase N-terminal domain AAA PF00004.29 KXT04342.1 - 0.038 14.4 0.4 0.51 10.8 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KXT04342.1 - 0.057 13.0 3.6 0.21 11.2 0.0 3.4 3 0 0 3 3 3 0 AAA domain TFR_dimer PF04253.15 KXT04342.1 - 0.88 9.7 5.2 8.7 6.5 0.3 3.4 2 0 0 2 2 2 0 Transferrin receptor-like dimerisation domain IBR PF01485.21 KXT04343.1 - 1.2 9.4 6.3 0.26 11.5 2.6 1.8 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Exo_endo_phos PF03372.23 KXT04344.1 - 1.8e-06 27.7 0.0 3.2e-06 26.8 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HET PF06985.11 KXT04345.1 - 8.4e-11 42.4 5.9 2e-07 31.5 1.1 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) ERCC4 PF02732.15 KXT04347.1 - 4.8e-18 65.9 0.0 9.4e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain Malate_synthase PF01274.22 KXT04348.1 - 2.1e-223 742.4 0.1 2.4e-223 742.2 0.1 1.0 1 0 0 1 1 1 1 Malate synthase SIR2 PF02146.17 KXT04360.1 - 3e-36 125.0 0.0 9.7e-36 123.3 0.0 1.7 1 1 0 1 1 1 1 Sir2 family zf-H2C2_2 PF13465.6 KXT04361.1 - 1.9e-14 53.3 19.7 1.2e-05 25.5 1.9 6.3 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXT04361.1 - 8.4e-12 44.9 33.5 0.0013 19.4 1.4 7.2 7 0 0 7 7 7 4 C2H2-type zinc finger zf-C2H2 PF00096.26 KXT04361.1 - 1.7e-10 40.7 44.3 0.00098 19.5 1.4 8.1 8 0 0 8 8 8 5 Zinc finger, C2H2 type FOXP-CC PF16159.5 KXT04361.1 - 8.5e-05 23.1 20.4 0.082 13.5 0.7 5.4 2 2 3 5 5 5 3 FOXP coiled-coil domain zf-Di19 PF05605.12 KXT04361.1 - 0.00022 21.5 30.5 0.043 14.1 2.7 4.8 4 2 0 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding DUF3984 PF13136.6 KXT04361.1 - 0.0071 15.8 1.6 0.012 15.1 1.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3984) zf-C2H2_9 PF16293.5 KXT04361.1 - 0.021 14.7 7.3 0.69 9.8 0.2 4.2 2 1 2 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-C2H2_6 PF13912.6 KXT04361.1 - 0.038 14.0 6.3 3.1 7.9 0.5 4.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf_Hakai PF18408.1 KXT04361.1 - 0.29 10.9 5.5 4.4 7.1 0.0 3.4 3 0 0 3 3 3 0 C2H2 Hakai zinc finger domain zf-H2C2_5 PF13909.6 KXT04361.1 - 0.49 10.2 0.0 0.49 10.2 0.0 5.9 6 1 0 6 6 6 0 C2H2-type zinc-finger domain UQ_con PF00179.26 KXT04362.1 - 2.7e-37 127.5 0.1 3.5e-37 127.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme FF PF01846.19 KXT04363.1 - 1.2e-07 31.8 0.1 1.2e-07 31.8 0.1 4.0 5 0 0 5 5 5 1 FF domain adh_short_C2 PF13561.6 KXT04364.1 - 5.8e-38 130.8 0.4 6.8e-38 130.5 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXT04364.1 - 1.2e-33 116.2 0.1 1.5e-33 115.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXT04364.1 - 2.7e-08 33.9 2.1 9e-08 32.2 2.1 1.7 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 KXT04364.1 - 0.01 14.9 0.2 0.015 14.5 0.2 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Epimerase PF01370.21 KXT04364.1 - 0.011 15.2 0.1 0.019 14.4 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family PRMT5 PF05185.16 KXT04364.1 - 0.1 12.4 0.2 0.28 11.0 0.1 1.6 1 1 1 2 2 2 0 PRMT5 arginine-N-methyltransferase PA PF02225.22 KXT04364.1 - 0.12 12.4 0.4 3.8 7.6 0.1 2.7 2 1 1 3 3 3 0 PA domain Flavokinase PF01687.17 KXT04365.1 - 7.2e-35 119.7 0.0 9.6e-35 119.3 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase PCI PF01399.27 KXT04366.1 - 2.2e-09 37.8 1.1 6.1e-09 36.3 0.1 2.4 2 0 0 2 2 2 1 PCI domain PAS PF00989.25 KXT04367.1 - 0.008 16.2 0.0 0.022 14.7 0.0 1.8 1 0 0 1 1 1 1 PAS fold Zn_clus PF00172.18 KXT04367.1 - 0.11 12.7 12.0 0.025 14.7 8.6 1.8 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KXT04368.1 - 7.9e-17 61.2 8.4 7.9e-17 61.2 8.4 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 KXT04369.1 - 8.7e-17 61.1 8.4 8.7e-17 61.1 8.4 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily LapA_dom PF06305.11 KXT04369.1 - 0.069 13.0 0.8 0.3 10.9 0.8 2.1 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Asp-Al_Ex PF06826.12 KXT04369.1 - 4.7 7.0 7.1 0.16 11.8 1.0 1.6 2 0 0 2 2 2 0 Predicted Permease Membrane Region MFS_1 PF07690.16 KXT04370.1 - 8e-17 61.2 8.4 8e-17 61.2 8.4 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily DHHA1 PF02272.19 KXT04371.1 - 0.058 13.8 0.0 0.45 10.9 0.0 2.2 2 0 0 2 2 2 0 DHHA1 domain HHH_2 PF12826.7 KXT04371.1 - 0.12 12.5 0.1 15 5.8 0.1 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix motif bZIP_1 PF00170.21 KXT04372.1 - 6.2e-06 26.2 10.6 9.2e-06 25.7 10.6 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXT04372.1 - 0.00027 21.0 12.3 0.00039 20.4 12.3 1.2 1 0 0 1 1 1 1 Basic region leucine zipper DUF4798 PF16055.5 KXT04372.1 - 0.0029 17.8 1.2 0.0058 16.9 1.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4798) HAUS-augmin3 PF14932.6 KXT04372.1 - 0.093 12.3 4.7 0.12 12.0 4.7 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 NAM-associated PF14303.6 KXT04372.1 - 0.14 12.9 6.0 0.19 12.5 6.0 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Herpes_UL56 PF04534.12 KXT04372.1 - 0.24 10.8 8.3 0.16 11.5 6.0 1.7 1 1 1 2 2 2 0 Herpesvirus UL56 protein bZIP_Maf PF03131.17 KXT04372.1 - 0.3 11.6 8.8 0.42 11.2 8.8 1.2 1 0 0 1 1 1 0 bZIP Maf transcription factor GrpE PF01025.19 KXT04372.1 - 0.32 10.6 3.5 0.42 10.3 3.5 1.2 1 0 0 1 1 1 0 GrpE Fringe PF02434.16 KXT04373.1 - 0.00077 19.0 0.1 0.03 13.8 0.0 2.7 2 1 0 2 2 2 1 Fringe-like HemY_N PF07219.13 KXT04373.1 - 0.039 14.2 0.0 0.066 13.4 0.0 1.3 1 0 0 1 1 1 0 HemY protein N-terminus PAN_2 PF08276.11 KXT04373.1 - 0.041 14.0 0.2 0.086 13.0 0.2 1.5 1 0 0 1 1 1 0 PAN-like domain Kelch_1 PF01344.25 KXT04373.1 - 0.095 12.3 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Kelch motif PAN_4 PF14295.6 KXT04373.1 - 0.1 12.5 0.6 0.25 11.3 0.6 1.6 1 0 0 1 1 1 0 PAN domain Proteasome PF00227.26 KXT04374.1 - 5.8e-61 205.3 0.2 7e-61 205.0 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KXT04374.1 - 4.2e-13 48.7 0.1 8.7e-13 47.7 0.1 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Nitrate_red_gam PF02665.14 KXT04374.1 - 0.0088 15.6 0.0 0.013 15.1 0.0 1.1 1 0 0 1 1 1 1 Nitrate reductase gamma subunit DUF5624 PF18538.1 KXT04374.1 - 0.029 14.5 0.5 0.082 13.0 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5624) Ank_2 PF12796.7 KXT04375.1 - 3.9e-48 161.9 10.8 1.9e-17 63.6 0.2 4.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXT04375.1 - 5.6e-39 132.0 9.5 2.8e-12 46.9 0.1 5.4 2 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXT04375.1 - 1.8e-38 126.2 9.0 3.2e-05 24.0 0.0 8.6 8 0 0 8 8 8 8 Ankyrin repeat Ank PF00023.30 KXT04375.1 - 1e-36 123.8 18.6 3.9e-05 23.9 0.0 8.4 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 KXT04375.1 - 1.9e-29 101.3 13.1 1.6e-07 31.5 0.1 7.3 1 1 7 8 8 8 7 Ankyrin repeats (many copies) DUF1843 PF08898.10 KXT04375.1 - 0.081 13.4 0.2 1.8 9.1 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) DUF3659 PF12396.8 KXT04376.1 - 3.1e-14 52.6 2.8 5.7e-14 51.8 2.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3659) DNA_pol_A_exo1 PF01612.20 KXT04376.1 - 5.3e-05 23.0 0.0 0.00015 21.6 0.0 1.7 2 0 0 2 2 2 1 3'-5' exonuclease IES5 PF17335.2 KXT04376.1 - 0.029 14.6 0.0 0.087 13.1 0.0 1.8 1 0 0 1 1 1 0 Ino80 complex subunit 5 XPG_I_2 PF12813.7 KXT04376.1 - 0.12 11.8 0.2 0.26 10.7 0.0 1.6 2 0 0 2 2 2 0 XPG domain containing DUF918 PF06033.11 KXT04377.1 - 0.2 11.7 0.0 7 6.6 0.0 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF918) SRP-alpha_N PF04086.13 KXT04378.1 - 3.8e-76 256.8 2.4 5.3e-76 256.3 2.4 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 KXT04378.1 - 1.4e-44 152.1 1.0 4.9e-44 150.3 1.0 2.0 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 KXT04378.1 - 7.2e-10 39.0 0.1 2.2e-09 37.4 0.1 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 KXT04378.1 - 5.4e-05 22.3 0.1 9.8e-05 21.5 0.1 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 KXT04378.1 - 0.002 18.6 0.3 0.011 16.1 0.0 2.4 2 1 1 3 3 3 1 AAA ATPase domain AAA_30 PF13604.6 KXT04378.1 - 0.011 15.5 0.1 0.025 14.3 0.1 1.6 1 0 0 1 1 1 0 AAA domain Fer4_NifH PF00142.18 KXT04378.1 - 0.022 14.2 0.0 0.052 13.0 0.0 1.6 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_31 PF13614.6 KXT04378.1 - 0.023 14.6 0.0 0.063 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain CinA PF02464.17 KXT04378.1 - 0.067 12.7 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 Competence-damaged protein NTPase_1 PF03266.15 KXT04378.1 - 0.07 13.0 0.2 0.4 10.6 0.1 2.2 2 0 0 2 2 2 0 NTPase ABC_tran PF00005.27 KXT04378.1 - 0.077 13.5 0.0 0.22 12.0 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 KXT04378.1 - 0.084 12.9 0.1 0.91 9.6 0.0 2.4 1 1 1 2 2 2 0 AAA domain CbiA PF01656.23 KXT04378.1 - 0.095 12.8 0.3 0.27 11.3 0.1 1.9 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 KXT04378.1 - 0.12 12.7 1.4 0.56 10.5 0.0 2.8 3 1 2 5 5 5 0 AAA domain MMR_HSR1 PF01926.23 KXT04378.1 - 0.13 12.4 0.3 0.72 10.0 0.3 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase Herpes_gE PF02480.16 KXT04379.1 - 0.0016 17.3 0.0 0.0017 17.2 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Sigma_reg_N PF13800.6 KXT04379.1 - 0.052 13.8 1.0 0.084 13.2 1.0 1.3 1 0 0 1 1 1 0 Sigma factor regulator N-terminal PIRT PF15099.6 KXT04379.1 - 0.065 12.8 0.4 0.11 12.1 0.4 1.4 1 1 0 1 1 1 0 Phosphoinositide-interacting protein family Mur_ligase_M PF08245.12 KXT04381.1 - 6.1e-07 29.6 0.0 0.55 10.2 0.0 3.4 2 1 1 3 3 3 3 Mur ligase middle domain DUF2188 PF09954.9 KXT04381.1 - 0.4 10.8 2.1 2.6 8.3 0.2 2.6 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2188) Peptidase_S64 PF08192.11 KXT04382.1 - 3.8 5.9 6.6 3.9 5.8 6.6 1.0 1 0 0 1 1 1 0 Peptidase family S64 CAP_GLY PF01302.25 KXT04383.1 - 3.5e-16 59.0 0.8 4.7e-15 55.4 0.2 2.4 2 0 0 2 2 2 1 CAP-Gly domain LRR_4 PF12799.7 KXT04383.1 - 7.1e-10 39.0 10.6 0.0038 17.6 0.3 5.2 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KXT04383.1 - 1.5e-08 34.3 9.1 0.00065 19.4 0.1 4.9 4 1 1 5 5 5 3 Leucine rich repeat LRR_9 PF14580.6 KXT04383.1 - 2.8e-06 26.9 0.5 0.1 12.1 0.0 3.1 3 0 0 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.6 KXT04383.1 - 0.00075 19.4 4.0 2.1 8.6 0.1 6.0 7 0 0 7 7 7 1 Leucine Rich repeat LRR_1 PF00560.33 KXT04383.1 - 0.54 11.0 5.2 79 4.4 0.0 5.1 6 1 0 6 6 6 0 Leucine Rich Repeat WLM PF08325.10 KXT04384.1 - 0.045 13.8 0.4 0.045 13.8 0.4 1.6 2 0 0 2 2 2 0 WLM domain PAF-AH_p_II PF03403.13 KXT04385.1 - 4.4e-39 134.1 0.0 4.6e-38 130.7 0.0 1.9 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KXT04385.1 - 1.3e-07 30.9 0.0 5.9e-07 28.6 0.0 1.9 1 1 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.7 KXT04385.1 - 2.1e-06 28.5 0.0 5e-06 27.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXT04385.1 - 6e-06 25.7 0.4 0.0022 17.3 0.0 2.6 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KXT04385.1 - 0.0044 16.9 0.0 0.0094 15.8 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase PF07224.11 KXT04385.1 - 0.011 14.8 0.0 0.036 13.1 0.0 1.7 2 0 0 2 2 2 0 Chlorophyllase Peptidase_S9 PF00326.21 KXT04385.1 - 0.034 13.6 0.4 1.4 8.3 0.1 2.7 2 1 1 3 3 3 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KXT04385.1 - 0.17 11.6 0.0 0.45 10.3 0.0 1.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Mitofilin PF09731.9 KXT04386.1 - 2.9e-133 446.0 31.8 7.1e-113 378.6 32.8 2.0 1 1 1 2 2 2 2 Mitochondrial inner membrane protein Pex14_N PF04695.13 KXT04386.1 - 0.028 15.1 1.7 0.028 15.1 1.7 3.1 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Mei5_like PF17021.5 KXT04386.1 - 0.12 12.4 2.9 0.23 11.5 2.5 1.6 1 1 0 1 1 1 0 Putative double-strand recombination repair-like Cas_DxTHG PF09455.10 KXT04386.1 - 0.21 11.1 9.2 0.31 10.6 9.2 1.2 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family Filament PF00038.21 KXT04386.1 - 0.75 9.3 22.6 0.43 10.1 17.7 2.3 1 1 1 2 2 2 0 Intermediate filament protein HBS1_N PF08938.10 KXT04386.1 - 1.2 9.4 10.7 4 7.8 1.5 3.6 3 1 0 3 3 3 0 HBS1 N-terminus Phage_Gp23 PF10669.9 KXT04386.1 - 6.7 7.1 14.1 34 4.8 13.3 2.3 1 1 1 2 2 2 0 Protein gp23 (Bacteriophage A118) G-gamma PF00631.22 KXT04387.1 - 4e-21 74.8 0.1 4.8e-21 74.5 0.1 1.1 1 0 0 1 1 1 1 GGL domain HLH PF00010.26 KXT04388.1 - 6.5e-13 48.4 0.5 1.6e-12 47.2 0.5 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SIKE PF05769.11 KXT04388.1 - 0.014 15.3 2.3 0.03 14.3 2.3 1.6 1 0 0 1 1 1 0 SIKE family DUF5094 PF17015.5 KXT04388.1 - 0.32 11.1 7.8 0.62 10.1 7.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) Pro_isomerase PF00160.21 KXT04389.1 - 1.3e-52 178.2 0.0 2e-52 177.6 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Flavoprotein PF02441.19 KXT04389.1 - 1.4e-19 70.3 0.0 2.4e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 Flavoprotein Sde2_N_Ubi PF13019.6 KXT04390.1 - 8.5e-64 214.3 0.9 8.5e-64 214.3 0.9 1.8 2 0 0 2 2 2 1 Silencing defective 2 N-terminal ubiquitin domain Arf PF00025.21 KXT04391.1 - 1.6e-79 265.4 0.1 1.9e-79 265.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KXT04391.1 - 2.5e-14 53.5 0.0 3.6e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KXT04391.1 - 3.7e-14 52.5 0.0 4.6e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KXT04391.1 - 1.9e-13 50.4 1.2 1.6e-09 37.4 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KXT04391.1 - 8.8e-13 48.2 0.0 9.5e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KXT04391.1 - 1.7e-10 40.7 0.0 2.1e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KXT04391.1 - 5e-06 26.6 0.0 7.8e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KXT04391.1 - 0.0098 15.2 0.5 0.022 14.1 0.5 1.7 1 1 0 1 1 1 1 6-phosphofructo-2-kinase C2 PF00168.30 KXT04393.1 - 9.1e-29 99.8 0.1 6.5e-17 61.7 0.0 3.1 3 0 0 3 3 3 2 C2 domain Copper-fist PF00649.18 KXT04394.1 - 4.8e-18 64.4 0.9 4.8e-18 64.4 0.9 2.5 2 1 1 3 3 3 1 Copper fist DNA binding domain Zn_clus PF00172.18 KXT04395.1 - 3.5e-09 36.6 9.2 3.5e-09 36.6 9.2 1.5 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXT04395.1 - 1.5e-05 24.1 0.0 2.7e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_cc PF11790.8 KXT04396.1 - 5.2e-62 209.5 0.5 6.4e-62 209.2 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core TYW3 PF02676.14 KXT04398.1 - 1.4e-69 233.7 0.0 1.7e-69 233.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 YIF1 PF03878.15 KXT04399.1 - 4.7e-96 320.9 2.5 5.5e-96 320.7 2.5 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 KXT04399.1 - 0.00076 19.2 3.8 0.00076 19.2 3.8 1.6 2 0 0 2 2 2 1 Yip1 domain SNF2_N PF00176.23 KXT04400.1 - 2.6e-69 233.6 0.0 4.8e-69 232.7 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 KXT04400.1 - 3.9e-19 68.4 0.0 8.8e-19 67.2 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 KXT04400.1 - 1.1e-14 54.7 0.0 3.3e-14 53.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 KXT04400.1 - 1.4e-09 37.6 8.2 3e-09 36.6 8.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXT04400.1 - 2.6e-09 37.2 7.1 2.6e-09 37.2 7.1 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 KXT04400.1 - 4.4e-09 36.1 8.3 1e-08 34.9 8.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXT04400.1 - 2.7e-08 33.5 4.6 2.7e-08 33.5 4.6 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXT04400.1 - 1.7e-07 31.2 5.4 3.8e-07 30.0 5.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 KXT04400.1 - 2.4e-07 30.9 3.8 8e-07 29.3 3.8 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KXT04400.1 - 3.7e-07 30.2 5.7 8.8e-07 29.0 5.7 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 KXT04400.1 - 8.3e-06 25.5 2.8 0.00011 21.9 3.8 2.1 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.6 KXT04400.1 - 1.5e-05 24.9 6.6 3.4e-05 23.7 6.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KXT04400.1 - 0.00021 21.1 5.9 0.00049 19.9 5.9 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 U-box PF04564.15 KXT04400.1 - 0.00062 19.9 0.0 0.0019 18.4 0.0 1.8 1 0 0 1 1 1 1 U-box domain ResIII PF04851.15 KXT04400.1 - 0.0012 18.8 0.0 0.0062 16.6 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-RING_11 PF17123.5 KXT04400.1 - 0.0025 17.5 2.3 0.0063 16.2 2.3 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 KXT04400.1 - 0.0049 16.9 0.9 0.012 15.7 0.9 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KXT04400.1 - 0.054 13.3 3.5 0.13 12.1 3.5 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain HDA2-3 PF11496.8 KXT04400.1 - 0.062 12.5 0.1 0.17 11.1 0.0 1.7 2 0 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 zf-RING_10 PF16685.5 KXT04400.1 - 0.063 13.4 3.3 0.17 12.0 3.3 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 Kelch_5 PF13854.6 KXT04401.1 - 1.2e-12 47.5 19.2 7.8e-10 38.5 0.1 5.6 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 KXT04401.1 - 5.3e-07 29.6 19.2 0.0017 18.3 0.4 5.8 6 1 1 7 7 7 3 Galactose oxidase, central domain Kelch_2 PF07646.15 KXT04401.1 - 7.4e-05 22.6 9.3 0.07 13.1 0.1 5.2 5 0 0 5 5 5 2 Kelch motif SKG6 PF08693.10 KXT04401.1 - 0.003 16.9 0.3 0.0058 16.0 0.3 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Kelch_1 PF01344.25 KXT04401.1 - 0.004 16.7 10.9 1.6 8.4 0.2 6.4 6 0 0 6 6 6 1 Kelch motif Kelch_3 PF13415.6 KXT04401.1 - 0.018 15.3 11.8 0.3 11.4 0.2 5.5 5 0 0 5 5 5 0 Galactose oxidase, central domain Podoplanin PF05808.11 KXT04401.1 - 0.039 14.0 0.2 0.076 13.1 0.2 1.4 1 0 0 1 1 1 0 Podoplanin EphA2_TM PF14575.6 KXT04401.1 - 0.059 14.2 0.0 0.29 12.1 0.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Kelch_6 PF13964.6 KXT04401.1 - 0.067 13.5 0.5 0.067 13.5 0.5 5.8 6 0 0 6 6 5 0 Kelch motif RIFIN PF02009.16 KXT04401.1 - 0.081 12.8 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Rifin Nitrate_red_gam PF02665.14 KXT04401.1 - 0.089 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Nitrate reductase gamma subunit DUF4690 PF15756.5 KXT04401.1 - 0.093 13.3 0.1 0.34 11.5 0.1 2.0 1 0 0 1 1 1 0 Small Novel Rich in Cartilage DAP10 PF07213.11 KXT04401.1 - 0.13 12.2 0.2 1.7 8.6 0.0 2.6 2 1 0 2 2 2 0 DAP10 membrane protein Herpes_gE PF02480.16 KXT04401.1 - 0.15 10.8 0.1 0.22 10.2 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E NAC PF01849.18 KXT04402.1 - 8.1e-24 83.4 0.4 1.6e-23 82.4 0.4 1.5 1 0 0 1 1 1 1 NAC domain adh_short PF00106.25 KXT04403.1 - 3e-26 92.1 0.0 1.8e-25 89.5 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT04403.1 - 2.8e-11 43.4 0.0 6.2e-11 42.3 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT04403.1 - 1.3e-09 38.2 0.0 2.3e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXT04403.1 - 8.6e-07 28.7 0.0 1.3e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXT04403.1 - 0.00035 20.1 0.1 0.0005 19.6 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KXT04403.1 - 0.00086 18.5 0.0 0.0012 18.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KXT04403.1 - 0.017 15.3 0.0 0.033 14.5 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KXT04403.1 - 0.093 12.8 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Apq12 PF12716.7 KXT04404.1 - 6e-21 74.1 10.2 8.3e-21 73.7 10.2 1.2 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis Methyltransf_11 PF08241.12 KXT04405.1 - 0.00016 22.2 0.0 0.00038 21.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXT04405.1 - 0.015 16.0 0.0 0.036 14.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 KXT04405.1 - 0.24 10.6 0.0 0.38 9.9 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Acetyltransf_1 PF00583.25 KXT04406.1 - 1.1e-06 28.8 0.0 1.7e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KXT04406.1 - 1.3e-05 25.5 0.0 2.1e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KXT04406.1 - 0.00025 21.0 0.1 0.00057 19.8 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KXT04406.1 - 0.058 13.5 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF572 PF04502.13 KXT04407.1 - 4.5e-64 217.2 1.1 5.3e-64 216.9 1.1 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Carboxyl_trans PF01039.22 KXT04407.1 - 0.029 13.0 1.6 0.038 12.6 1.6 1.1 1 0 0 1 1 1 0 Carboxyl transferase domain CorA PF01544.18 KXT04408.1 - 5e-05 22.8 5.2 0.17 11.1 0.1 3.2 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein SieB PF14163.6 KXT04408.1 - 0.093 12.2 4.7 0.94 9.0 2.8 2.9 3 0 0 3 3 3 0 Super-infection exclusion protein B Pkinase PF00069.25 KXT04409.1 - 1.7e-61 207.9 0.0 2.5e-61 207.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT04409.1 - 1.6e-31 109.5 0.0 2.3e-31 109.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXT04409.1 - 8.4e-05 22.0 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KXT04409.1 - 0.00046 19.6 0.1 0.00087 18.7 0.1 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXT04409.1 - 0.0019 18.1 0.5 0.015 15.2 0.1 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXT04409.1 - 0.0031 16.3 0.2 0.007 15.2 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Endonuc_Holl PF10107.9 KXT04409.1 - 0.031 14.1 0.2 0.46 10.3 0.0 2.1 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase Haspin_kinase PF12330.8 KXT04409.1 - 0.16 10.8 0.1 0.24 10.3 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain MA3 PF02847.17 KXT04410.1 - 1.7e-24 85.9 0.0 5e-24 84.5 0.0 1.9 1 0 0 1 1 1 1 MA3 domain DUF3835 PF12927.7 KXT04410.1 - 4.7e-20 72.2 1.1 4.7e-20 72.2 1.1 5.6 5 0 0 5 5 5 1 Domain of unknown function (DUF3835) Prefoldin_3 PF13758.6 KXT04410.1 - 1.5e-19 69.9 1.7 1.5e-19 69.9 1.7 2.7 2 0 0 2 2 2 1 Prefoldin subunit MIF4G PF02854.19 KXT04410.1 - 1.1e-10 41.5 1.8 1.1e-10 41.5 1.8 2.1 2 0 0 2 2 2 1 MIF4G domain Prefoldin_2 PF01920.20 KXT04410.1 - 0.00059 19.7 6.4 0.82 9.7 1.5 3.9 3 0 0 3 3 3 2 Prefoldin subunit YqjK PF13997.6 KXT04410.1 - 0.051 13.8 1.4 0.14 12.4 1.4 1.8 1 0 0 1 1 1 0 YqjK-like protein FliD_N PF02465.18 KXT04410.1 - 0.082 13.6 1.5 12 6.7 0.4 3.1 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Cnd1 PF12717.7 KXT04410.1 - 0.082 12.9 0.9 0.17 11.9 0.9 1.4 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 APG12 PF04110.13 KXT04412.1 - 4.1e-14 52.8 0.0 6.1e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Pep1_7 PF17232.2 KXT04412.1 - 0.36 11.3 2.9 0.78 10.2 1.3 2.0 2 0 0 2 2 2 0 Elicitor peptide 1-7 DPM2 PF07297.12 KXT04413.1 - 1.9e-27 95.4 5.8 2.2e-18 66.3 0.2 2.1 2 0 0 2 2 2 2 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) COX14 PF14880.6 KXT04413.1 - 0.0011 18.7 0.0 0.0011 18.7 0.0 2.0 2 0 0 2 2 2 1 Cytochrome oxidase c assembly DUF1275 PF06912.11 KXT04413.1 - 0.0093 15.9 0.4 0.012 15.6 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) LapA_dom PF06305.11 KXT04413.1 - 0.012 15.5 0.4 0.012 15.5 0.4 1.9 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF4229 PF14012.6 KXT04413.1 - 0.016 15.3 1.0 0.016 15.3 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) DiS_P_DiS PF06750.13 KXT04413.1 - 0.098 12.8 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain PIG-P PF08510.12 KXT04413.1 - 0.18 11.7 7.0 0.49 10.3 7.0 1.6 1 1 0 1 1 1 0 PIG-P ECH_1 PF00378.20 KXT04414.1 - 4.7e-41 140.7 0.0 5.7e-41 140.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXT04414.1 - 2.8e-20 73.1 0.0 3.4e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Methyltransf_PK PF05891.12 KXT04417.1 - 4.2e-75 252.0 0.0 5e-75 251.8 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.6 KXT04417.1 - 6.2e-09 35.9 0.0 1e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXT04417.1 - 0.00012 22.7 0.0 0.00025 21.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXT04417.1 - 0.021 15.4 0.0 0.046 14.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain WD40 PF00400.32 KXT04418.1 - 3.2e-23 81.6 6.0 3.1e-06 27.8 0.7 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXT04418.1 - 3.8e-06 27.1 0.0 0.059 13.7 0.0 4.1 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain CDC45 PF02724.14 KXT04418.1 - 5.2 5.2 18.8 0.34 9.2 9.5 2.2 2 0 0 2 2 2 0 CDC45-like protein NRDE-2 PF08424.10 KXT04419.1 - 0.043 12.9 4.8 0.056 12.6 4.8 1.1 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference Tho2 PF11262.8 KXT04419.1 - 0.19 10.9 2.0 0.25 10.5 2.0 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 ADH_N PF08240.12 KXT04420.1 - 5.1e-07 29.5 0.1 6.8e-07 29.1 0.1 1.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.6 KXT04420.1 - 2.4e-05 24.2 0.0 3.7e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated DUF4350 PF14258.6 KXT04421.1 - 0.12 12.8 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4350) DUF1604 PF07713.13 KXT04422.1 - 4.7e-39 132.1 4.4 8.7e-39 131.2 2.6 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch PF01585.23 KXT04422.1 - 1.1e-05 25.2 4.3 2.2e-05 24.3 2.4 2.5 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 KXT04422.1 - 0.07 13.2 2.5 0.2 11.8 0.5 2.9 4 0 0 4 4 4 0 G-patch domain Arf PF00025.21 KXT04424.1 - 5.7e-63 211.5 0.0 7e-63 211.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KXT04424.1 - 2.2e-10 40.2 0.0 7.7e-07 28.6 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KXT04424.1 - 2.7e-07 30.2 0.0 3.5e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KXT04424.1 - 7.5e-07 29.4 0.0 2.8e-06 27.6 0.0 1.9 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KXT04424.1 - 2.8e-06 27.4 0.0 4e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 KXT04424.1 - 1e-05 25.2 0.0 1.4e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KXT04424.1 - 0.0023 17.3 0.0 0.0029 17.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PTS_2-RNA PF01885.16 KXT04425.1 - 4.5e-67 225.6 0.0 5.3e-67 225.4 0.0 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family PIP5K PF01504.18 KXT04426.1 - 1.1e-37 129.8 2.0 5.6e-30 104.5 0.3 2.5 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 KXT04426.1 - 1.2e-26 93.5 0.0 1.9e-26 92.8 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 KXT04426.1 - 6e-14 51.9 3.8 6e-14 51.9 3.8 2.4 2 1 0 2 2 2 1 FYVE zinc finger DUF1366 PF07104.11 KXT04426.1 - 0.079 12.7 0.2 0.23 11.1 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1366) C1_1 PF00130.22 KXT04426.1 - 0.13 12.1 10.1 0.051 13.5 3.9 2.8 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.7 KXT04426.1 - 0.63 10.1 9.2 0.33 11.0 5.0 2.5 2 0 0 2 2 2 0 Double zinc ribbon PHY PF00360.20 KXT04427.1 - 2.2e-28 98.8 0.0 7.2e-28 97.1 0.0 1.8 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.26 KXT04427.1 - 3.6e-18 66.1 0.1 8.4e-18 64.9 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXT04427.1 - 4.5e-16 59.0 0.0 4e-15 56.0 0.0 2.6 1 1 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KXT04427.1 - 1.5e-12 47.4 0.7 6e-12 45.4 0.7 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 KXT04427.1 - 2.4e-12 47.6 0.0 2.5e-11 44.4 0.0 2.5 3 0 0 3 3 3 1 GAF domain PAS_2 PF08446.11 KXT04427.1 - 1.2e-09 38.8 0.0 3.8e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 PAS fold HATPase_c_3 PF13589.6 KXT04427.1 - 0.031 14.1 0.0 0.084 12.7 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PHY PF00360.20 KXT04428.1 - 2.2e-28 98.8 0.0 7.2e-28 97.1 0.0 1.8 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.26 KXT04428.1 - 3.6e-18 66.1 0.1 8.4e-18 64.9 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXT04428.1 - 4.5e-16 59.0 0.0 4e-15 56.0 0.0 2.6 1 1 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KXT04428.1 - 1.5e-12 47.4 0.7 6e-12 45.4 0.7 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 KXT04428.1 - 2.4e-12 47.6 0.0 2.5e-11 44.4 0.0 2.5 3 0 0 3 3 3 1 GAF domain PAS_2 PF08446.11 KXT04428.1 - 1.2e-09 38.8 0.0 3.8e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 PAS fold HATPase_c_3 PF13589.6 KXT04428.1 - 0.031 14.1 0.0 0.084 12.7 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PHY PF00360.20 KXT04429.1 - 2.2e-28 98.8 0.0 7.2e-28 97.1 0.0 1.8 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.26 KXT04429.1 - 3.6e-18 66.1 0.1 8.4e-18 64.9 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXT04429.1 - 4.5e-16 59.0 0.0 4e-15 56.0 0.0 2.6 1 1 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KXT04429.1 - 1.5e-12 47.4 0.7 6e-12 45.4 0.7 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 KXT04429.1 - 2.4e-12 47.6 0.0 2.5e-11 44.4 0.0 2.5 3 0 0 3 3 3 1 GAF domain PAS_2 PF08446.11 KXT04429.1 - 1.2e-09 38.8 0.0 3.8e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 PAS fold HATPase_c_3 PF13589.6 KXT04429.1 - 0.031 14.1 0.0 0.084 12.7 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PHY PF00360.20 KXT04430.1 - 2.2e-28 98.8 0.0 7.2e-28 97.1 0.0 1.8 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.26 KXT04430.1 - 3.6e-18 66.1 0.1 8.4e-18 64.9 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXT04430.1 - 4.5e-16 59.0 0.0 4e-15 56.0 0.0 2.6 1 1 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KXT04430.1 - 1.5e-12 47.4 0.7 6e-12 45.4 0.7 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 KXT04430.1 - 2.4e-12 47.6 0.0 2.5e-11 44.4 0.0 2.5 3 0 0 3 3 3 1 GAF domain PAS_2 PF08446.11 KXT04430.1 - 1.2e-09 38.8 0.0 3.8e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 PAS fold HATPase_c_3 PF13589.6 KXT04430.1 - 0.031 14.1 0.0 0.084 12.7 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3506 PF12014.8 KXT04431.1 - 3.1e-52 176.3 0.0 4.7e-51 172.5 0.0 2.7 3 1 0 3 3 3 1 Domain of unknown function (DUF3506) F-box-like PF12937.7 KXT04431.1 - 2.4e-10 40.2 0.3 4.9e-10 39.2 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXT04431.1 - 4.6e-07 29.5 0.1 8.4e-07 28.7 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KXT04431.1 - 0.00028 20.8 0.0 0.00054 19.8 0.0 1.4 1 0 0 1 1 1 1 F-box zf-C2H2_2 PF12756.7 KXT04432.1 - 6.8e-36 122.6 10.8 3.8e-30 104.2 3.5 3.5 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KXT04432.1 - 2.7e-08 33.9 15.5 0.00013 22.1 0.4 4.0 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXT04432.1 - 4.9e-05 23.6 0.6 4.9e-05 23.6 0.6 3.7 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KXT04432.1 - 0.0088 16.4 28.5 0.075 13.5 0.6 5.4 5 0 0 5 5 5 2 Zinc finger, C2H2 type SnoaL_2 PF12680.7 KXT04432.1 - 0.011 16.4 0.2 0.039 14.6 0.2 1.9 1 0 0 1 1 1 0 SnoaL-like domain Mso1_Sec1_bdg PF14475.6 KXT04432.1 - 0.068 12.8 0.1 0.25 10.9 0.1 2.0 1 0 0 1 1 1 0 Sec1-binding region of Mso1 Phage_tail_APC PF16778.5 KXT04432.1 - 0.12 12.2 0.3 11 6.0 0.2 2.8 2 0 0 2 2 2 0 Phage tail assembly chaperone protein zf-FLZ PF04570.14 KXT04432.1 - 1.2 8.7 4.2 4.2 6.9 0.1 3.0 3 0 0 3 3 3 0 zinc-finger of the FCS-type, C2-C2 Peptidase_C14 PF00656.22 KXT04433.1 - 4.7e-41 141.4 0.0 6.1e-41 141.0 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Peptidase_M20 PF01546.28 KXT04434.1 - 8.6e-26 90.9 0.0 1.5e-25 90.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KXT04434.1 - 1.4e-06 28.1 0.0 3.5e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KXT04434.1 - 0.074 12.7 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M28 NARP1 PF12569.8 KXT04435.1 - 1.3e-190 634.8 17.1 1.3e-190 634.8 17.1 2.8 4 0 0 4 4 4 2 NMDA receptor-regulated protein 1 TPR_16 PF13432.6 KXT04435.1 - 2.6e-20 72.8 14.6 0.013 16.1 0.7 9.2 7 1 2 9 9 9 7 Tetratricopeptide repeat TPR_19 PF14559.6 KXT04435.1 - 2.2e-19 69.7 22.7 0.0046 17.4 0.0 7.7 7 0 0 7 7 7 5 Tetratricopeptide repeat ANAPC3 PF12895.7 KXT04435.1 - 2.4e-15 56.5 19.8 0.00014 22.0 0.7 6.2 5 1 1 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KXT04435.1 - 1.7e-14 53.2 16.4 0.13 13.2 0.1 10.8 7 4 5 12 12 11 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXT04435.1 - 2.4e-12 46.0 45.3 0.0018 18.3 0.0 11.5 13 0 0 13 13 11 4 Tetratricopeptide repeat TPR_1 PF00515.28 KXT04435.1 - 4.2e-11 42.2 23.5 0.0001 22.0 0.0 9.4 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_17 PF13431.6 KXT04435.1 - 1.4e-07 31.4 2.8 4.7 7.8 0.0 7.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXT04435.1 - 3.8e-07 29.7 11.1 0.00011 21.8 0.1 6.7 7 0 0 7 7 7 1 TPR repeat TPR_9 PF13371.6 KXT04435.1 - 8.4e-07 29.1 12.6 0.029 14.5 1.9 6.0 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KXT04435.1 - 6.4e-06 25.8 10.1 0.0056 16.1 2.7 3.4 2 1 1 3 3 3 2 MalT-like TPR region TPR_7 PF13176.6 KXT04435.1 - 3.5e-05 23.5 8.6 6.9 6.9 0.0 6.4 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KXT04435.1 - 6.3e-05 22.9 36.3 0.05 13.8 0.0 9.7 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_12 PF13424.6 KXT04435.1 - 7.5e-05 23.0 25.6 0.53 10.6 0.3 8.0 5 2 3 8 8 8 3 Tetratricopeptide repeat TPR_4 PF07721.14 KXT04435.1 - 9.5e-05 22.7 0.3 0.25 12.1 0.1 4.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_3 PF07720.12 KXT04435.1 - 0.00011 22.1 0.2 0.16 12.0 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KXT04435.1 - 0.037 14.7 15.1 39 5.2 0.0 8.1 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_10 PF13374.6 KXT04435.1 - 0.08 12.8 10.9 11 6.0 0.0 6.5 6 0 0 6 6 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KXT04435.1 - 0.088 12.9 16.8 2 8.5 0.1 6.1 8 0 0 8 8 8 0 Fis1 C-terminal tetratricopeptide repeat Adaptin_N PF01602.20 KXT04436.1 - 8.1e-142 473.4 0.2 9.6e-142 473.2 0.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 KXT04436.1 - 7.8e-23 80.9 0.4 2.4e-22 79.3 0.4 1.8 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 KXT04436.1 - 3.1e-09 37.1 3.4 3e-05 24.1 0.0 4.4 2 2 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KXT04436.1 - 3.1e-07 30.7 0.4 0.44 11.0 0.0 4.3 3 1 0 3 3 3 3 HEAT repeats HEAT PF02985.22 KXT04436.1 - 0.00026 21.0 0.9 2.5 8.6 0.0 4.4 3 0 0 3 3 3 1 HEAT repeat DUF3730 PF12530.8 KXT04436.1 - 0.0025 17.4 0.1 0.082 12.5 0.0 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF3730) RICTOR_M PF14666.6 KXT04436.1 - 0.055 13.3 0.0 0.16 11.8 0.0 1.9 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain Dynactin_p62 PF05502.13 KXT04437.1 - 5.2e-145 483.9 11.3 1.2e-95 321.1 0.0 2.0 1 1 1 2 2 2 2 Dynactin p62 family Prok-RING_2 PF14445.6 KXT04437.1 - 1.5 9.0 8.2 0.2 11.8 3.2 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 Rdx PF10262.9 KXT04438.1 - 6.1e-32 109.6 0.0 8.7e-32 109.2 0.0 1.2 1 0 0 1 1 1 1 Rdx family Pyr_redox_3 PF13738.6 KXT04439.1 - 9.7e-11 41.5 0.0 2.3e-08 33.6 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KXT04439.1 - 2.6e-10 39.4 0.1 4.4e-09 35.3 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KXT04439.1 - 1.1e-07 31.9 0.0 3.6e-07 30.3 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KXT04439.1 - 5.4e-06 25.8 0.0 0.0007 18.8 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pkinase PF00069.25 KXT04440.1 - 2.7e-70 236.8 0.0 4.9e-70 235.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT04440.1 - 1.1e-39 136.3 0.0 2.6e-39 135.1 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 KXT04440.1 - 3.3e-20 71.6 0.1 5.5e-20 70.9 0.1 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Haspin_kinase PF12330.8 KXT04440.1 - 1.5e-05 24.1 0.7 3.8e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 KXT04440.1 - 4.1e-05 23.0 0.0 7.2e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXT04440.1 - 5.4e-05 22.6 0.0 0.00036 19.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KXT04440.1 - 0.00087 19.3 0.3 0.058 13.3 0.0 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 KXT04440.1 - 0.074 12.6 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL ABC1 PF03109.16 KXT04440.1 - 0.075 13.2 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 ABC1 family WaaY PF06176.11 KXT04440.1 - 0.094 12.3 0.1 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.22 KXT04440.1 - 0.15 11.6 0.2 0.52 9.9 0.2 1.8 1 1 0 1 1 1 0 RIO1 family Pkinase PF00069.25 KXT04441.1 - 2.7e-70 236.8 0.0 4.9e-70 235.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT04441.1 - 1.1e-39 136.3 0.0 2.6e-39 135.1 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 KXT04441.1 - 3.3e-20 71.6 0.1 5.5e-20 70.9 0.1 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Haspin_kinase PF12330.8 KXT04441.1 - 1.5e-05 24.1 0.7 3.8e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 KXT04441.1 - 4.1e-05 23.0 0.0 7.2e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXT04441.1 - 5.4e-05 22.6 0.0 0.00036 19.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KXT04441.1 - 0.00087 19.3 0.3 0.058 13.3 0.0 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 KXT04441.1 - 0.074 12.6 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL ABC1 PF03109.16 KXT04441.1 - 0.075 13.2 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 ABC1 family WaaY PF06176.11 KXT04441.1 - 0.094 12.3 0.1 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.22 KXT04441.1 - 0.15 11.6 0.2 0.52 9.9 0.2 1.8 1 1 0 1 1 1 0 RIO1 family Pkinase PF00069.25 KXT04442.1 - 2.7e-70 236.8 0.0 4.9e-70 235.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT04442.1 - 1.1e-39 136.3 0.0 2.6e-39 135.1 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 KXT04442.1 - 3.3e-20 71.6 0.1 5.5e-20 70.9 0.1 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Haspin_kinase PF12330.8 KXT04442.1 - 1.5e-05 24.1 0.7 3.8e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 KXT04442.1 - 4.1e-05 23.0 0.0 7.2e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXT04442.1 - 5.4e-05 22.6 0.0 0.00036 19.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KXT04442.1 - 0.00087 19.3 0.3 0.058 13.3 0.0 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 KXT04442.1 - 0.074 12.6 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL ABC1 PF03109.16 KXT04442.1 - 0.075 13.2 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 ABC1 family WaaY PF06176.11 KXT04442.1 - 0.094 12.3 0.1 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.22 KXT04442.1 - 0.15 11.6 0.2 0.52 9.9 0.2 1.8 1 1 0 1 1 1 0 RIO1 family Pkinase PF00069.25 KXT04443.1 - 2.7e-70 236.8 0.0 4.9e-70 235.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT04443.1 - 1.1e-39 136.3 0.0 2.6e-39 135.1 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 KXT04443.1 - 3.3e-20 71.6 0.1 5.5e-20 70.9 0.1 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Haspin_kinase PF12330.8 KXT04443.1 - 1.5e-05 24.1 0.7 3.8e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 KXT04443.1 - 4.1e-05 23.0 0.0 7.2e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KXT04443.1 - 5.4e-05 22.6 0.0 0.00036 19.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KXT04443.1 - 0.00087 19.3 0.3 0.058 13.3 0.0 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 KXT04443.1 - 0.074 12.6 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL ABC1 PF03109.16 KXT04443.1 - 0.075 13.2 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 ABC1 family WaaY PF06176.11 KXT04443.1 - 0.094 12.3 0.1 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.22 KXT04443.1 - 0.15 11.6 0.2 0.52 9.9 0.2 1.8 1 1 0 1 1 1 0 RIO1 family 2OG-FeII_Oxy_3 PF13640.6 KXT04444.1 - 3e-08 34.4 0.0 6.5e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFMR_assoc PF16596.5 KXT04444.1 - 0.07 13.6 1.1 0.18 12.3 1.1 1.6 1 0 0 1 1 1 0 Disordered region downstream of MFMR NOA36 PF06524.12 KXT04444.1 - 1.3 8.2 22.2 1.4 8.2 6.4 2.4 2 0 0 2 2 2 0 NOA36 protein GP24_25 PF17388.2 KXT04444.1 - 2.2 8.3 5.5 18 5.4 0.1 2.6 2 0 0 2 2 2 0 Tail assembly gene products 24 & 25 DUF2457 PF10446.9 KXT04444.1 - 2.3 7.3 16.9 1.6 7.8 4.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) 2OG-FeII_Oxy_3 PF13640.6 KXT04445.1 - 3e-08 34.4 0.0 6.5e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFMR_assoc PF16596.5 KXT04445.1 - 0.07 13.6 1.1 0.18 12.3 1.1 1.6 1 0 0 1 1 1 0 Disordered region downstream of MFMR NOA36 PF06524.12 KXT04445.1 - 1.3 8.2 22.2 1.4 8.2 6.4 2.4 2 0 0 2 2 2 0 NOA36 protein GP24_25 PF17388.2 KXT04445.1 - 2.2 8.3 5.5 18 5.4 0.1 2.6 2 0 0 2 2 2 0 Tail assembly gene products 24 & 25 DUF2457 PF10446.9 KXT04445.1 - 2.3 7.3 16.9 1.6 7.8 4.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Ribosomal_L1 PF00687.21 KXT04446.1 - 7.7e-46 156.4 0.3 8.7e-46 156.2 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family FKBP_N_2 PF18023.1 KXT04446.1 - 0.13 12.3 0.2 0.57 10.3 0.0 2.0 2 0 0 2 2 2 0 BDBT FKBP like N-terminal Dfp1_Him1_M PF08630.10 KXT04447.1 - 8.4e-40 135.9 0.6 2.6e-39 134.3 0.0 2.2 2 0 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.12 KXT04447.1 - 4.7e-20 71.4 0.1 9.2e-20 70.5 0.1 1.5 1 0 0 1 1 1 1 DBF zinc finger PTCB-BRCT PF12738.7 KXT04447.1 - 0.014 15.4 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 twin BRCT domain BRCT PF00533.26 KXT04447.1 - 0.037 14.4 0.0 0.11 12.9 0.0 1.9 1 1 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Acetyltransf_7 PF13508.7 KXT04448.1 - 8.9e-07 29.3 0.0 1.4e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXT04448.1 - 2.8e-06 27.5 0.0 4.1e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KXT04448.1 - 3.9e-05 23.6 0.0 5.5e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KXT04448.1 - 7.7e-05 22.6 0.0 0.00013 21.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein TPP1 PF10341.9 KXT04449.1 - 1.9e-10 40.7 0.0 3.6e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD ATP-synt_F PF01990.17 KXT04449.1 - 0.028 14.7 0.3 0.061 13.6 0.3 1.6 1 0 0 1 1 1 0 ATP synthase (F/14-kDa) subunit PAS_9 PF13426.7 KXT04450.1 - 6e-16 58.6 0.0 6.7e-15 55.2 0.0 2.4 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 KXT04450.1 - 4.1e-06 26.8 0.0 8.7e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 KXT04450.1 - 0.01 16.0 0.0 0.028 14.7 0.0 1.7 1 0 0 1 1 1 0 PAS fold UCH_1 PF13423.6 KXT04451.1 - 6.9e-87 292.0 0.3 9.9e-87 291.5 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 KXT04451.1 - 4.8e-16 59.7 0.0 8.8e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 Exonuclease ANAPC4_WD40 PF12894.7 KXT04451.1 - 0.00086 19.6 0.0 0.02 15.2 0.0 3.0 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain p450 PF00067.22 KXT04464.1 - 7.5e-07 28.2 0.0 9.6e-07 27.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.6 KXT04465.1 - 3.7e-57 193.6 0.0 4.6e-57 193.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXT04465.1 - 2.8e-43 147.7 0.0 3.4e-43 147.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXT04465.1 - 0.00012 22.0 0.3 0.0002 21.3 0.3 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXT04465.1 - 0.053 13.0 0.1 0.47 9.9 0.1 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Methyltransf_31 PF13847.6 KXT04465.1 - 0.17 11.7 0.1 0.43 10.4 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase domain ATP12 PF07542.11 KXT04466.1 - 4.2e-44 149.7 0.9 4.2e-44 149.7 0.9 2.0 2 0 0 2 2 2 1 ATP12 chaperone protein GST_C_2 PF13410.6 KXT04467.1 - 0.00012 22.1 0.0 0.00025 21.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXT04467.1 - 0.00015 21.9 0.0 0.00027 21.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KXT04467.1 - 0.07 13.6 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain ER_lumen_recept PF00810.18 KXT04469.1 - 1.1e-54 185.3 1.0 1.6e-54 184.7 1.0 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 KXT04469.1 - 0.0071 16.1 4.0 2.3 8.1 0.2 3.8 3 1 1 4 4 4 2 PQ loop repeat ArAE_2_N PF10337.9 KXT04470.1 - 1.7e-41 142.8 24.5 1e-33 117.2 0.2 5.0 3 1 1 4 4 4 3 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 KXT04470.1 - 6e-16 58.7 12.6 6e-16 58.7 12.6 3.6 3 0 0 3 3 3 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 KXT04470.1 - 2.4e-08 34.1 0.1 8.1e-08 32.4 0.1 1.9 1 1 0 1 1 1 1 Aromatic acid exporter family member 2 Pdase_M17_N2 PF18295.1 KXT04471.1 - 0.13 12.5 0.0 0.75 10.1 0.0 2.0 2 0 0 2 2 2 0 M17 aminopeptidase N-terminal domain 2 DUF5572 PF17733.1 KXT04472.1 - 1.6e-24 85.4 0.7 2.4e-24 84.9 0.7 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5572) Fungal_trans PF04082.18 KXT04473.1 - 1.2e-25 90.1 0.0 3.8e-24 85.2 0.0 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT04473.1 - 6.4e-07 29.4 9.0 1.2e-06 28.5 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ATG27 PF09451.10 KXT04474.1 - 5.8e-93 311.6 0.0 6.9e-93 311.3 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 NACHT PF05729.12 KXT04475.1 - 2.8e-06 27.4 0.0 5.1e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KXT04475.1 - 4.7e-05 23.7 0.0 8.9e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXT04475.1 - 0.0001 22.7 0.0 0.00024 21.5 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain Torsin PF06309.11 KXT04475.1 - 0.00062 19.9 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 Torsin Zeta_toxin PF06414.12 KXT04475.1 - 0.0013 18.1 0.0 0.0048 16.2 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin RNA_helicase PF00910.22 KXT04475.1 - 0.0059 17.0 0.0 0.012 16.0 0.0 1.6 1 1 0 1 1 1 1 RNA helicase AAA PF00004.29 KXT04475.1 - 0.014 15.8 0.0 0.048 14.1 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 KXT04475.1 - 0.08 12.3 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_25 PF13481.6 KXT04475.1 - 0.088 12.4 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KXT04475.1 - 0.15 11.3 0.0 0.3 10.3 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Cid2 PF09774.9 KXT04475.1 - 0.23 11.9 2.5 0.54 10.7 0.9 2.1 2 0 0 2 2 2 0 Caffeine-induced death protein 2 PNP_UDP_1 PF01048.20 KXT04476.1 - 5.8e-07 29.0 0.6 1.4e-06 27.8 0.6 1.6 1 1 0 1 1 1 1 Phosphorylase superfamily Ank_2 PF12796.7 KXT04477.1 - 7e-14 52.2 0.0 2.1e-05 25.0 0.0 3.8 2 1 2 4 4 4 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXT04477.1 - 6.2e-11 42.3 0.0 1.8e-05 24.9 0.0 3.1 1 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXT04477.1 - 1e-09 37.8 0.0 0.017 15.6 0.0 4.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 KXT04477.1 - 7.7e-09 35.9 0.2 5.9e-06 26.7 0.0 3.7 3 1 1 4 4 3 1 Ankyrin repeats (many copies) NACHT PF05729.12 KXT04477.1 - 2.2e-08 34.2 0.0 4.9e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KXT04477.1 - 0.00013 22.2 0.0 0.00029 21.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXT04477.1 - 0.00059 20.2 0.0 0.0018 18.6 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Ank PF00023.30 KXT04477.1 - 0.00068 20.0 0.0 0.31 11.5 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Torsin PF06309.11 KXT04477.1 - 0.0017 18.5 0.0 0.006 16.7 0.0 1.9 2 0 0 2 2 2 1 Torsin Zeta_toxin PF06414.12 KXT04477.1 - 0.0073 15.6 0.0 0.021 14.1 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin AAA PF00004.29 KXT04477.1 - 0.0086 16.5 0.0 0.024 15.0 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KXT04477.1 - 0.028 14.8 0.0 0.057 13.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Ank_2 PF12796.7 KXT04478.1 - 3.4e-14 53.2 0.0 1.4e-05 25.6 0.0 3.4 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KXT04478.1 - 2.3e-11 43.7 0.0 1.1e-05 25.6 0.0 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXT04478.1 - 2.4e-10 39.7 0.0 0.011 16.2 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 KXT04478.1 - 4e-09 36.8 0.3 3.7e-06 27.4 0.0 3.5 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 KXT04478.1 - 0.00025 21.4 0.0 0.2 12.1 0.0 3.5 4 0 0 4 4 4 1 Ankyrin repeat PNP_UDP_1 PF01048.20 KXT04479.1 - 5.8e-07 29.0 0.6 1.4e-06 27.8 0.6 1.6 1 1 0 1 1 1 1 Phosphorylase superfamily PNP_UDP_1 PF01048.20 KXT04480.1 - 6.1e-07 28.9 0.8 1.4e-06 27.7 0.8 1.6 1 1 0 1 1 1 1 Phosphorylase superfamily CN_hydrolase PF00795.22 KXT04481.1 - 9.7e-47 159.5 0.0 1.2e-46 159.2 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase CN_hydrolase PF00795.22 KXT04482.1 - 9.7e-47 159.5 0.0 1.2e-46 159.2 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase RhoGAP PF00620.27 KXT04484.1 - 2.2e-48 164.0 0.1 5.7e-48 162.6 0.0 1.7 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.22 KXT04484.1 - 5.5e-14 52.1 16.3 2.1e-09 37.5 1.7 2.3 2 0 0 2 2 2 2 LIM domain KELK PF15796.5 KXT04484.1 - 0.33 11.4 10.9 0.12 12.9 0.9 2.7 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase CENP-H PF05837.12 KXT04484.1 - 0.54 10.7 0.0 0.54 10.7 0.0 3.2 3 0 0 3 3 3 0 Centromere protein H (CENP-H) DUF4407 PF14362.6 KXT04484.1 - 0.55 9.5 3.9 2.3 7.5 3.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Fez1 PF06818.15 KXT04484.1 - 0.81 10.1 12.1 0.82 10.1 7.3 2.6 1 1 1 2 2 2 0 Fez1 DUF5082 PF16888.5 KXT04484.1 - 1.4 9.2 6.9 2.9 8.2 1.4 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Desulfoferrod_N PF06397.12 KXT04484.1 - 1.8 8.3 10.3 11 5.8 0.7 3.5 2 1 1 3 3 3 0 Desulfoferrodoxin, N-terminal domain ZapB PF06005.12 KXT04484.1 - 2.3 8.7 10.8 12 6.4 1.9 3.4 2 1 0 2 2 2 0 Cell division protein ZapB Seryl_tRNA_N PF02403.22 KXT04484.1 - 2.4 8.4 10.4 0.28 11.4 0.4 3.1 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Zn-ribbon_8 PF09723.10 KXT04484.1 - 4.2 7.6 19.1 1.2 9.3 1.2 4.1 3 1 1 4 4 4 0 Zinc ribbon domain zf-ribbon_3 PF13248.6 KXT04484.1 - 9.8 5.7 16.5 0.86 9.1 0.0 3.8 5 1 0 5 5 5 0 zinc-ribbon domain AIM3 PF17096.5 KXT04485.1 - 0.0019 19.1 0.6 0.0019 19.1 0.6 5.0 5 1 0 5 5 5 2 Altered inheritance of mitochondria protein 3 DUF2142 PF09913.9 KXT04487.1 - 0.047 12.5 0.0 0.052 12.4 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) Glyco_hydro_12 PF01670.16 KXT04488.1 - 7.5e-38 130.7 11.1 9e-38 130.4 11.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 PPV_E2_C PF00511.17 KXT04488.1 - 0.27 11.5 9.2 2.4 8.4 1.9 2.5 1 1 1 2 2 2 0 E2 (early) protein, C terminal Phage_holin_5_1 PF06946.11 KXT04488.1 - 1.5 9.3 6.6 0.44 11.0 1.8 2.3 1 1 1 2 2 2 0 Bacteriophage A118-like holin, Hol118 Ge1_WD40 PF16529.5 KXT04489.1 - 5.9e-05 22.2 0.0 0.00019 20.5 0.0 1.7 1 1 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein MgtE_N PF03448.17 KXT04489.1 - 0.029 15.0 3.8 0.45 11.1 0.5 2.7 2 0 0 2 2 2 0 MgtE intracellular N domain MOR2-PAG1_C PF14225.6 KXT04489.1 - 0.076 12.9 1.9 2.3 8.0 0.2 2.4 2 0 0 2 2 2 0 Cell morphogenesis C-terminal DUF445 PF04286.12 KXT04489.1 - 0.11 12.2 12.3 0.047 13.5 9.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF445) DUF2937 PF11157.8 KXT04489.1 - 0.12 12.0 8.3 0.38 10.4 8.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) SPT_ssu-like PF11779.8 KXT04490.1 - 1.7e-22 78.8 3.1 2.9e-22 78.0 3.1 1.4 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like NdhL PF10716.9 KXT04490.1 - 0.059 13.3 2.0 0.059 13.3 0.3 1.8 1 1 1 2 2 2 0 NADH dehydrogenase transmembrane subunit CT_A_B PF02626.15 KXT04491.1 - 7.5e-78 261.8 0.0 1.6e-77 260.7 0.0 1.6 2 0 0 2 2 2 1 Carboxyltransferase domain, subdomain A and B CPSase_L_D2 PF02786.17 KXT04491.1 - 1.3e-54 184.9 0.0 2.4e-54 184.0 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KXT04491.1 - 4.9e-39 133.3 0.5 1.1e-38 132.2 0.0 1.9 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain CT_C_D PF02682.16 KXT04491.1 - 2.4e-31 109.1 0.0 5e-31 108.0 0.0 1.5 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D Biotin_carb_C PF02785.19 KXT04491.1 - 2.2e-29 101.7 0.0 4.1e-29 100.8 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KXT04491.1 - 4e-08 33.0 1.9 1.3e-07 31.3 1.9 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KXT04491.1 - 2e-07 30.7 0.0 4.2e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 KXT04491.1 - 0.017 15.0 7.7 0.072 12.9 0.2 3.4 3 1 1 4 4 4 0 Biotin-lipoyl like ATP-grasp PF02222.22 KXT04491.1 - 0.082 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain FMN_dh PF01070.18 KXT04492.1 - 9.7e-76 255.0 1.3 3.1e-41 141.6 0.1 2.2 1 1 1 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.25 KXT04492.1 - 0.00097 18.2 0.8 0.025 13.6 0.1 2.2 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KXT04492.1 - 0.018 14.2 0.3 0.066 12.3 0.2 1.8 1 1 1 2 2 2 0 Conserved region in glutamate synthase DHO_dh PF01180.21 KXT04492.1 - 0.059 12.6 0.4 3.8 6.6 0.0 2.7 3 0 0 3 3 3 0 Dihydroorotate dehydrogenase His_biosynth PF00977.21 KXT04492.1 - 0.068 12.6 0.0 0.3 10.5 0.0 2.0 2 0 0 2 2 2 0 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 KXT04492.1 - 0.19 11.1 0.0 17 4.7 0.0 2.2 2 0 0 2 2 2 0 Ribulose-phosphate 3 epimerase family GTP_EFTU PF00009.27 KXT04493.1 - 3.1e-19 69.3 0.1 1.3e-18 67.3 0.0 2.0 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KXT04493.1 - 2.4e-10 40.7 2.8 2.5e-09 37.4 2.0 2.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 KXT04493.1 - 0.00017 21.9 0.0 0.00043 20.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 KXT04493.1 - 0.0025 17.9 0.1 0.0085 16.2 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 KXT04493.1 - 0.0072 16.1 0.6 1.1 9.0 0.1 3.3 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 KXT04493.1 - 0.12 12.2 4.5 2.8 7.8 0.0 3.0 4 0 0 4 4 4 0 RsgA GTPase Dynamin_N PF00350.23 KXT04493.1 - 0.2 11.7 2.0 0.87 9.6 0.7 2.4 2 0 0 2 2 2 0 Dynamin family eIF-3c_N PF05470.12 KXT04493.1 - 0.32 9.3 0.5 2.4 6.3 0.1 1.9 1 1 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus HAGH_C PF16123.5 KXT04494.1 - 3.2e-19 69.2 0.2 5.2e-19 68.5 0.2 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 KXT04494.1 - 1.6e-18 67.4 4.9 1e-17 64.8 4.9 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KXT04494.1 - 0.0016 18.0 1.6 0.011 15.3 1.6 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Peripla_BP_4 PF13407.6 KXT04494.1 - 0.011 15.3 0.1 0.025 14.2 0.1 1.5 1 0 0 1 1 1 0 Periplasmic binding protein domain BcrAD_BadFG PF01869.20 KXT04494.1 - 0.15 11.5 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family Lactamase_B PF00753.27 KXT04495.1 - 8.3e-20 71.6 4.1 5.4e-19 69.0 4.1 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily HAGH_C PF16123.5 KXT04495.1 - 2.9e-19 69.4 0.2 4.8e-19 68.6 0.2 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B_2 PF12706.7 KXT04495.1 - 0.0013 18.3 1.6 0.0086 15.6 1.6 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Peripla_BP_4 PF13407.6 KXT04495.1 - 0.011 15.4 0.1 0.024 14.2 0.1 1.5 1 0 0 1 1 1 0 Periplasmic binding protein domain BcrAD_BadFG PF01869.20 KXT04495.1 - 0.13 11.7 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family GTP_EFTU PF00009.27 KXT04496.1 - 3.1e-19 69.3 0.1 1.3e-18 67.3 0.0 2.0 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KXT04496.1 - 2.4e-10 40.7 2.8 2.5e-09 37.4 2.0 2.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 KXT04496.1 - 0.00017 21.9 0.0 0.00043 20.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 KXT04496.1 - 0.0025 17.9 0.1 0.0085 16.2 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 KXT04496.1 - 0.0072 16.1 0.6 1.1 9.0 0.1 3.3 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 KXT04496.1 - 0.12 12.2 4.5 2.8 7.8 0.0 3.0 4 0 0 4 4 4 0 RsgA GTPase Dynamin_N PF00350.23 KXT04496.1 - 0.2 11.7 2.0 0.87 9.6 0.7 2.4 2 0 0 2 2 2 0 Dynamin family eIF-3c_N PF05470.12 KXT04496.1 - 0.32 9.3 0.5 2.4 6.3 0.1 1.9 1 1 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Lactamase_B PF00753.27 KXT04497.1 - 8.3e-20 71.6 4.1 5.4e-19 69.0 4.1 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily HAGH_C PF16123.5 KXT04497.1 - 2.9e-19 69.4 0.2 4.8e-19 68.6 0.2 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B_2 PF12706.7 KXT04497.1 - 0.0013 18.3 1.6 0.0086 15.6 1.6 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Peripla_BP_4 PF13407.6 KXT04497.1 - 0.011 15.4 0.1 0.024 14.2 0.1 1.5 1 0 0 1 1 1 0 Periplasmic binding protein domain BcrAD_BadFG PF01869.20 KXT04497.1 - 0.13 11.7 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family GTP_EFTU PF00009.27 KXT04498.1 - 3.1e-19 69.3 0.1 1.3e-18 67.3 0.0 2.0 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KXT04498.1 - 2.4e-10 40.7 2.8 2.5e-09 37.4 2.0 2.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 KXT04498.1 - 0.00017 21.9 0.0 0.00043 20.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 KXT04498.1 - 0.0025 17.9 0.1 0.0085 16.2 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 KXT04498.1 - 0.0072 16.1 0.6 1.1 9.0 0.1 3.3 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 KXT04498.1 - 0.12 12.2 4.5 2.8 7.8 0.0 3.0 4 0 0 4 4 4 0 RsgA GTPase Dynamin_N PF00350.23 KXT04498.1 - 0.2 11.7 2.0 0.87 9.6 0.7 2.4 2 0 0 2 2 2 0 Dynamin family eIF-3c_N PF05470.12 KXT04498.1 - 0.32 9.3 0.5 2.4 6.3 0.1 1.9 1 1 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Na_H_Exchanger PF00999.21 KXT04499.1 - 1.8e-45 155.4 15.7 2.3e-45 155.0 15.7 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family 7TM_GPCR_Srv PF10323.9 KXT04499.1 - 0.041 13.3 0.1 0.15 11.4 0.0 1.8 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv TIP49 PF06068.13 KXT04500.1 - 3.9e-152 506.5 0.5 4.9e-152 506.2 0.5 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KXT04500.1 - 9.4e-22 76.9 0.1 2.4e-21 75.6 0.1 1.8 1 0 0 1 1 1 1 TIP49 AAA-lid domain RuvB_N PF05496.12 KXT04500.1 - 6.6e-08 32.4 0.3 0.00068 19.4 0.0 2.3 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 KXT04500.1 - 8.3e-07 29.5 0.3 0.0047 17.3 0.0 2.9 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.15 KXT04500.1 - 0.0007 19.0 0.2 0.0013 18.2 0.2 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 KXT04500.1 - 0.0026 18.1 0.3 0.012 16.1 0.3 2.2 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 KXT04500.1 - 0.0037 16.7 0.6 0.085 12.2 0.2 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 KXT04500.1 - 0.019 15.3 3.4 0.6 10.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain Sigma54_activat PF00158.26 KXT04500.1 - 0.041 13.6 0.1 11 5.7 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_22 PF13401.6 KXT04500.1 - 0.044 14.0 0.0 1.2 9.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KXT04500.1 - 0.11 12.3 0.7 0.49 10.1 0.7 2.0 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KXT04500.1 - 0.11 12.7 0.0 0.3 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Hydin_ADK PF17213.3 KXT04500.1 - 1.5 9.1 4.1 0.41 10.9 0.1 2.1 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain LSM14 PF12701.7 KXT04501.1 - 1.8e-27 95.3 0.2 2.9e-27 94.5 0.2 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 KXT04501.1 - 4.5e-16 59.6 0.9 1.3e-15 58.1 0.9 1.8 1 0 0 1 1 1 1 FDF domain SM-ATX PF14438.6 KXT04501.1 - 9e-05 22.5 0.1 0.00016 21.8 0.1 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM PF01423.22 KXT04501.1 - 0.0032 17.1 0.0 0.0051 16.5 0.0 1.3 1 0 0 1 1 1 1 LSM domain TIP49 PF06068.13 KXT04502.1 - 3.9e-152 506.5 0.5 4.9e-152 506.2 0.5 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KXT04502.1 - 9.4e-22 76.9 0.1 2.4e-21 75.6 0.1 1.8 1 0 0 1 1 1 1 TIP49 AAA-lid domain RuvB_N PF05496.12 KXT04502.1 - 6.6e-08 32.4 0.3 0.00068 19.4 0.0 2.3 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 KXT04502.1 - 8.3e-07 29.5 0.3 0.0047 17.3 0.0 2.9 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.15 KXT04502.1 - 0.0007 19.0 0.2 0.0013 18.2 0.2 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 KXT04502.1 - 0.0026 18.1 0.3 0.012 16.1 0.3 2.2 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 KXT04502.1 - 0.0037 16.7 0.6 0.085 12.2 0.2 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 KXT04502.1 - 0.019 15.3 3.4 0.6 10.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain Sigma54_activat PF00158.26 KXT04502.1 - 0.041 13.6 0.1 11 5.7 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_22 PF13401.6 KXT04502.1 - 0.044 14.0 0.0 1.2 9.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KXT04502.1 - 0.11 12.3 0.7 0.49 10.1 0.7 2.0 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KXT04502.1 - 0.11 12.7 0.0 0.3 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Hydin_ADK PF17213.3 KXT04502.1 - 1.5 9.1 4.1 0.41 10.9 0.1 2.1 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain DUF3488 PF11992.8 KXT04503.1 - 0.019 13.9 0.4 0.023 13.6 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) HA2 PF04408.23 KXT04504.1 - 2.2e-23 82.6 2.4 2.9e-23 82.2 0.0 2.6 2 0 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KXT04504.1 - 2.7e-13 50.2 0.0 1.7e-10 41.3 0.0 3.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KXT04504.1 - 1e-08 35.4 0.0 2.1e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KXT04504.1 - 2.5e-08 33.9 0.2 7e-08 32.4 0.2 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KXT04504.1 - 0.00049 20.4 0.2 0.0053 17.0 0.0 2.7 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.18 KXT04504.1 - 0.0038 16.6 0.0 0.0078 15.6 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family T2SSE PF00437.20 KXT04504.1 - 0.0043 16.2 0.0 0.009 15.1 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 KXT04504.1 - 0.0095 15.7 1.1 0.024 14.4 0.2 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KXT04504.1 - 0.016 15.5 0.1 0.038 14.3 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KXT04504.1 - 0.028 14.6 0.4 0.12 12.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 KXT04504.1 - 0.074 12.5 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Vps52 PF04129.12 KXT04505.1 - 9.4e-124 413.9 0.0 1.3e-123 413.5 0.0 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 KXT04505.1 - 0.0006 18.3 0.5 0.0009 17.8 0.5 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec3 Mer2 PF09074.10 KXT04505.1 - 0.0032 17.3 3.5 0.015 15.1 0.4 2.9 4 0 0 4 4 4 1 Mer2 Xrn1_D3 PF18194.1 KXT04505.1 - 0.0039 17.2 4.7 0.15 12.2 0.5 2.8 2 0 0 2 2 2 2 Exoribonuclease 1 Domain-3 COG6 PF06419.11 KXT04505.1 - 0.023 12.9 3.7 0.019 13.2 2.3 1.6 2 0 0 2 2 2 0 Conserved oligomeric complex COG6 BST2 PF16716.5 KXT04505.1 - 0.024 15.2 0.5 0.074 13.6 0.5 1.8 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 ABC_tran_CTD PF16326.5 KXT04505.1 - 0.029 14.6 0.6 0.82 10.0 0.2 2.9 2 1 0 2 2 2 0 ABC transporter C-terminal domain DUF4349 PF14257.6 KXT04505.1 - 0.051 13.0 0.0 0.17 11.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) CCDC144C PF14915.6 KXT04505.1 - 0.068 12.3 2.3 0.12 11.5 2.3 1.3 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region BAR PF03114.18 KXT04505.1 - 0.076 12.6 0.6 9 5.9 0.0 2.5 2 1 0 2 2 2 0 BAR domain Sec34 PF04136.15 KXT04505.1 - 0.082 12.8 3.2 0.15 12.0 0.1 2.5 3 0 0 3 3 3 0 Sec34-like family Cluap1 PF10234.9 KXT04505.1 - 0.1 12.0 2.3 0.2 11.1 2.3 1.4 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF1664 PF07889.12 KXT04505.1 - 0.34 11.0 2.5 0.25 11.4 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) BSP PF04450.12 KXT04506.1 - 1.4e-68 230.8 0.0 1.7e-68 230.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase of plants and bacteria ACBP PF00887.19 KXT04507.1 - 6e-22 77.7 0.0 1.2e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein DUF4381 PF14316.6 KXT04507.1 - 0.033 14.4 4.2 0.088 13.0 4.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Cor1 PF04803.12 KXT04507.1 - 0.39 10.9 3.5 0.19 11.9 1.0 1.7 2 0 0 2 2 2 0 Cor1/Xlr/Xmr conserved region NINJA_B PF16136.5 KXT04507.1 - 0.56 10.6 10.3 0.046 14.1 3.0 2.3 2 0 0 2 2 2 0 Putative nuclear localisation signal TLV_coat PF00429.19 KXT04507.1 - 0.72 8.4 1.8 1.1 7.8 1.8 1.2 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) LamB_YcsF PF03746.16 KXT04508.1 - 8.4e-83 277.7 0.0 9.5e-83 277.5 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family Abhydrolase_4 PF08386.10 KXT04508.1 - 0.072 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein ResIII PF04851.15 KXT04509.1 - 1.2e-22 80.7 0.0 2.9e-22 79.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KXT04509.1 - 7.3e-13 48.8 0.0 2.2e-11 44.1 0.0 3.0 3 1 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 KXT04509.1 - 6.6e-12 45.5 0.0 8e-11 42.0 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KXT04509.1 - 0.0043 16.8 0.1 0.0076 15.9 0.1 1.5 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 KXT04509.1 - 0.033 14.5 0.0 0.13 12.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain zf-RRN7 PF11781.8 KXT04514.1 - 2.7e-08 33.4 3.0 4.8e-08 32.5 3.0 1.5 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Sld5 PF05916.11 KXT04514.1 - 0.034 14.6 0.1 0.12 12.8 0.0 1.9 2 0 0 2 2 2 0 GINS complex protein SPX PF03105.19 KXT04514.1 - 0.34 10.8 3.7 5.6 6.8 0.3 2.1 2 0 0 2 2 2 0 SPX domain SAF PF08666.12 KXT04515.1 - 5.5e-08 33.3 0.0 1.3e-07 32.2 0.0 1.7 1 0 0 1 1 1 1 SAF domain NAD_binding_3 PF03447.16 KXT04515.1 - 3.3e-05 24.5 0.1 0.00027 21.6 0.1 2.4 2 1 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 KXT04515.1 - 7.4e-05 23.6 0.1 0.00018 22.3 0.1 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.20 KXT04515.1 - 0.00011 22.3 0.1 0.00053 20.1 0.1 2.1 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Gp_dh_N PF00044.24 KXT04515.1 - 0.016 15.5 0.0 0.071 13.5 0.0 2.1 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain HAD_2 PF13419.6 KXT04516.1 - 7.3e-12 45.7 0.0 1e-11 45.3 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXT04516.1 - 1.5e-10 41.7 0.0 5.1e-10 40.0 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KXT04516.1 - 0.0039 17.2 0.0 0.0065 16.5 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 KXT04516.1 - 0.0054 17.2 0.0 0.007 16.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase MFS_1 PF07690.16 KXT04521.1 - 7.2e-31 107.4 32.8 8.5e-31 107.1 32.4 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily RRM_1 PF00076.22 KXT04522.1 - 1.6e-59 197.7 0.0 1.3e-20 73.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXT04522.1 - 1.5e-12 47.2 0.0 4.1e-05 23.2 0.0 3.3 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXT04522.1 - 1.7e-07 31.0 0.0 0.0086 15.9 0.0 3.5 3 1 0 3 3 3 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KXT04522.1 - 3e-06 27.1 0.1 0.71 9.9 0.0 3.4 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.10 KXT04522.1 - 0.00018 21.5 0.0 0.8 9.8 0.0 2.4 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) RRM_7 PF16367.5 KXT04522.1 - 0.00042 20.4 0.1 1 9.6 0.0 3.4 3 1 0 3 3 3 2 RNA recognition motif RRM_8 PF11835.8 KXT04522.1 - 0.0019 18.4 0.0 1.7 8.9 0.0 2.3 2 0 0 2 2 2 2 RRM-like domain RRM_3 PF08777.11 KXT04522.1 - 0.092 12.8 0.0 1.7 8.7 0.0 2.6 3 0 0 3 3 3 0 RNA binding motif SET_assoc PF11767.8 KXT04522.1 - 0.15 11.7 0.0 6.4 6.5 0.0 2.3 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated RRM_1 PF00076.22 KXT04523.1 - 1.6e-59 197.7 0.0 1.3e-20 73.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KXT04523.1 - 1.5e-12 47.2 0.0 4.1e-05 23.2 0.0 3.3 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXT04523.1 - 1.7e-07 31.0 0.0 0.0086 15.9 0.0 3.5 3 1 0 3 3 3 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KXT04523.1 - 3e-06 27.1 0.1 0.71 9.9 0.0 3.4 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.10 KXT04523.1 - 0.00018 21.5 0.0 0.8 9.8 0.0 2.4 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) RRM_7 PF16367.5 KXT04523.1 - 0.00042 20.4 0.1 1 9.6 0.0 3.4 3 1 0 3 3 3 2 RNA recognition motif RRM_8 PF11835.8 KXT04523.1 - 0.0019 18.4 0.0 1.7 8.9 0.0 2.3 2 0 0 2 2 2 2 RRM-like domain RRM_3 PF08777.11 KXT04523.1 - 0.092 12.8 0.0 1.7 8.7 0.0 2.6 3 0 0 3 3 3 0 RNA binding motif SET_assoc PF11767.8 KXT04523.1 - 0.15 11.7 0.0 6.4 6.5 0.0 2.3 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated Cyclin_N PF00134.23 KXT04525.1 - 7.7e-42 142.0 0.2 1.8e-41 140.8 0.2 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KXT04525.1 - 1.1e-31 109.4 0.0 2.7e-31 108.1 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain TFIIA PF03153.13 KXT04525.1 - 6.8 6.6 11.4 9.6 6.1 11.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cyclin_N PF00134.23 KXT04526.1 - 1.2e-41 141.4 0.2 2.8e-41 140.2 0.2 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KXT04526.1 - 1.6e-31 108.9 0.0 4.1e-31 107.5 0.0 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain DASH_Ask1 PF08655.10 KXT04527.1 - 1e-30 105.4 0.6 1.5e-30 104.8 0.6 1.3 1 0 0 1 1 1 1 DASH complex subunit Ask1 PH PF00169.29 KXT04528.1 - 2.5e-29 101.9 3.2 3.6e-14 53.2 0.6 2.2 2 0 0 2 2 2 2 PH domain PH_9 PF15410.6 KXT04528.1 - 1.2e-09 38.6 5.3 2.8e-05 24.4 1.0 3.6 2 2 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.6 KXT04528.1 - 1.2e-09 38.5 8.4 0.00034 21.0 0.6 3.7 2 2 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.6 KXT04528.1 - 2.7e-07 30.6 3.2 5e-05 23.3 1.0 2.4 2 1 0 2 2 2 2 PH domain PH_8 PF15409.6 KXT04528.1 - 3.3e-05 24.1 1.1 0.00019 21.6 0.2 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain Mcp5_PH PF12814.7 KXT04528.1 - 0.00018 21.6 1.5 0.028 14.5 0.1 2.3 2 0 0 2 2 2 2 Meiotic cell cortex C-terminal pleckstrin homology PH_2 PF08458.10 KXT04528.1 - 0.087 13.2 1.2 4.4 7.7 0.1 2.6 2 1 0 2 2 2 0 Plant pleckstrin homology-like region PH_13 PF16652.5 KXT04528.1 - 0.17 11.7 2.7 0.16 11.8 0.4 2.0 3 0 0 3 3 3 0 Pleckstrin homology domain PH_12 PF16457.5 KXT04528.1 - 0.25 11.9 1.4 19 5.8 0.0 2.8 2 1 0 2 2 2 0 Pleckstrin homology domain TPR_12 PF13424.6 KXT04529.1 - 0.078 13.3 0.4 0.15 12.3 0.4 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Phi-29_GP3 PF05435.11 KXT04529.1 - 0.21 11.0 0.9 0.36 10.3 0.9 1.3 1 0 0 1 1 1 0 Phi-29 DNA terminal protein GP3 KH_1 PF00013.29 KXT04531.1 - 2.2e-29 101.1 7.7 7.6e-07 28.9 0.2 7.6 9 0 0 9 9 9 5 KH domain DUF2012 PF09430.10 KXT04532.1 - 1.6e-28 99.3 0.0 2e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) SOP4 PF17081.5 KXT04532.1 - 0.00011 21.8 0.1 0.0013 18.3 0.1 2.0 1 1 0 1 1 1 1 Suppressor of PMA 1-7 protein F-box PF00646.33 KXT04533.1 - 1e-08 34.8 0.1 2.8e-08 33.5 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXT04533.1 - 5.9e-06 26.1 0.2 1.9e-05 24.5 0.2 1.9 1 0 0 1 1 1 1 F-box-like Hce2 PF14856.6 KXT04534.1 - 1.8e-16 60.3 0.4 2.7e-16 59.7 0.4 1.3 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor DUF2407 PF10302.9 KXT04535.1 - 0.0016 19.0 0.6 0.0078 16.8 0.6 2.3 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 KXT04535.1 - 0.002 17.9 0.0 0.002 17.9 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin family PulG PF11773.8 KXT04535.1 - 1.1 9.2 3.9 3.4 7.6 3.9 1.8 1 0 0 1 1 1 0 Type II secretory pathway pseudopilin DUF3176 PF11374.8 KXT04536.1 - 4.2e-18 65.5 1.6 7.9e-18 64.6 1.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Rad51 PF08423.11 KXT04537.1 - 0.026 13.8 0.1 0.052 12.8 0.1 1.4 1 0 0 1 1 1 0 Rad51 DcpS_C PF11969.8 KXT04538.1 - 1.7e-14 54.3 1.7 9.6e-14 51.8 1.7 2.0 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 KXT04538.1 - 5.3e-14 52.7 0.0 1.4e-13 51.4 0.0 1.7 1 1 0 1 1 1 1 HIT domain zf-C2HE PF16278.5 KXT04538.1 - 3.6e-13 49.7 0.6 8.4e-13 48.6 0.6 1.7 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger DUF4351 PF14261.6 KXT04538.1 - 0.034 14.2 0.2 0.06 13.4 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4351) OMPdecase PF00215.24 KXT04539.1 - 1.2e-77 260.5 0.0 1.5e-77 260.2 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Cue1_U7BR PF18499.1 KXT04539.1 - 0.11 12.6 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Ubc7p-binding region of Cue1 PI3K_1B_p101 PF10486.9 KXT04539.1 - 0.23 9.2 3.2 0.31 8.8 3.2 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF3246 PF11596.8 KXT04539.1 - 0.31 10.5 4.2 0.79 9.1 4.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3246) WD40 PF00400.32 KXT04540.1 - 2.4e-42 142.1 13.0 0.001 19.8 0.0 11.9 12 0 0 12 12 12 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXT04540.1 - 3.5e-10 40.1 4.4 0.71 10.2 0.1 8.1 5 2 6 11 11 11 4 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 KXT04540.1 - 0.00012 22.1 0.2 0.54 10.3 0.0 4.4 5 0 0 5 5 5 2 Ciliary BBSome complex subunit 2, middle region DUF4596 PF15363.6 KXT04540.1 - 0.017 15.4 0.1 0.078 13.2 0.1 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4596) SAD_SRA PF02182.17 KXT04541.1 - 7.3e-08 32.3 0.2 6.7e-07 29.1 0.2 2.1 1 1 0 1 1 1 1 SAD/SRA domain CCDC117 PF15810.5 KXT04541.1 - 0.16 12.2 0.0 0.28 11.5 0.0 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 117 FAD_binding_3 PF01494.19 KXT04542.1 - 4e-11 42.8 0.3 0.00036 19.9 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain Pyr_redox_2 PF07992.14 KXT04542.1 - 2e-05 24.0 0.3 0.029 13.6 0.4 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXT04542.1 - 6.4e-05 23.1 0.1 0.0002 21.5 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXT04542.1 - 0.00011 21.4 0.2 0.00018 20.7 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KXT04542.1 - 0.0029 16.4 0.1 0.0068 15.2 0.1 1.5 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 KXT04542.1 - 0.0071 15.7 0.1 0.015 14.7 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KXT04542.1 - 0.015 14.4 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A DAO PF01266.24 KXT04542.1 - 0.024 14.2 0.1 0.063 12.8 0.2 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF1989 PF09347.10 KXT04543.1 - 1.1e-64 217.0 0.0 1.4e-64 216.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) Arm PF00514.23 KXT04544.1 - 5.6e-08 32.6 7.3 0.58 10.3 0.1 7.3 8 0 0 8 8 8 3 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KXT04544.1 - 0.0047 17.1 10.1 9.3 6.8 0.2 6.3 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 KXT04544.1 - 1.1 9.7 8.5 4.9 7.6 0.1 5.0 4 1 0 4 4 4 0 HEAT repeats RL10P_insert PF17777.1 KXT04545.1 - 3.6e-23 81.3 0.0 1.2e-22 79.7 0.0 1.8 2 0 0 2 2 2 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 KXT04545.1 - 1.8e-17 63.3 0.0 3.5e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 CRT10 PF08728.10 KXT04546.1 - 8.6e-13 47.4 0.0 7.6e-09 34.3 0.0 2.6 3 0 0 3 3 3 2 CRT10 DUF3104 PF11302.8 KXT04547.1 - 0.092 12.5 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) DUF1640 PF07798.11 KXT04548.1 - 7.1e-41 140.2 9.1 7.1e-41 140.2 9.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1640) DUF4407 PF14362.6 KXT04548.1 - 0.29 10.4 14.1 1.3 8.4 4.6 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) DUF3112 PF11309.8 KXT04549.1 - 3.3e-16 59.4 0.2 5.4e-08 32.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) YoqO PF14037.6 KXT04549.1 - 0.042 14.4 0.5 0.042 14.4 0.5 2.7 3 0 0 3 3 3 0 YoqO-like protein MAP17 PF15807.5 KXT04549.1 - 3.8 7.8 0.0 3.8 7.8 0.0 3.0 4 0 0 4 4 4 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 BP28CT PF08146.12 KXT04550.1 - 3.9e-34 117.8 1.4 9.9e-34 116.5 0.4 2.3 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 KXT04550.1 - 6.8e-24 84.5 3.0 6.8e-24 84.5 3.0 4.4 3 2 2 5 5 5 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.22 KXT04550.1 - 0.0058 16.8 11.5 0.73 10.3 0.2 5.6 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 KXT04550.1 - 0.011 16.2 3.0 0.52 10.9 0.4 4.3 3 0 0 3 3 3 0 HEAT-like repeat Cnd1 PF12717.7 KXT04550.1 - 0.027 14.5 0.6 6.6 6.8 0.1 3.2 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 GMC_oxred_C PF05199.13 KXT04552.1 - 2.2e-08 34.7 0.1 6.4e-08 33.2 0.1 1.6 1 1 1 2 2 2 1 GMC oxidoreductase Peptidase_C69 PF03577.15 KXT04554.1 - 4.1e-19 68.8 0.0 6.2e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C69 adh_short_C2 PF13561.6 KXT04557.1 - 1.1e-55 188.8 7.9 1.3e-55 188.5 7.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXT04557.1 - 7.2e-45 152.8 7.8 9.3e-45 152.5 7.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_25 PF13649.6 KXT04557.1 - 0.0068 17.1 0.1 0.016 15.9 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXT04557.1 - 0.016 15.9 0.1 0.038 14.6 0.1 1.7 1 0 0 1 1 1 0 Methyltransferase domain 3HCDH_N PF02737.18 KXT04557.1 - 0.079 12.8 1.0 0.16 11.8 1.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Zn_clus PF00172.18 KXT04558.1 - 0.00092 19.3 11.5 0.0017 18.5 11.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.10 KXT04558.1 - 0.046 13.2 1.1 0.079 12.4 0.0 1.9 2 0 0 2 2 2 0 Histone chaperone domain CHZ DSPc PF00782.20 KXT04559.1 - 2.3e-28 98.7 0.0 2.7e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KXT04559.1 - 0.00033 20.8 0.0 0.00051 20.2 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Init_tRNA_PT PF04179.12 KXT04559.1 - 0.0024 18.2 0.0 0.0033 17.7 0.0 1.2 1 0 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase3 PF13350.6 KXT04559.1 - 0.011 15.7 0.1 0.024 14.6 0.0 1.6 2 0 0 2 2 2 0 Tyrosine phosphatase family Y_phosphatase PF00102.27 KXT04559.1 - 0.014 15.0 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Rhodanese PF00581.20 KXT04559.1 - 0.019 15.5 0.0 0.033 14.7 0.0 1.4 1 0 0 1 1 1 0 Rhodanese-like domain adh_short PF00106.25 KXT04560.1 - 5.6e-53 179.3 1.6 6.7e-53 179.0 1.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT04560.1 - 2.9e-49 167.8 2.7 5.1e-49 166.9 2.7 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT04560.1 - 1e-12 48.4 0.3 1.8e-12 47.5 0.3 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXT04560.1 - 0.0018 17.8 0.2 0.0053 16.2 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ATP_bind_2 PF03668.15 KXT04560.1 - 0.095 12.0 0.1 0.16 11.3 0.1 1.2 1 0 0 1 1 1 0 P-loop ATPase protein family adh_short PF00106.25 KXT04561.1 - 5.6e-53 179.3 1.6 6.7e-53 179.0 1.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT04561.1 - 2.9e-49 167.8 2.7 5.1e-49 166.9 2.7 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT04561.1 - 1e-12 48.4 0.3 1.8e-12 47.5 0.3 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXT04561.1 - 0.0018 17.8 0.2 0.0053 16.2 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ATP_bind_2 PF03668.15 KXT04561.1 - 0.095 12.0 0.1 0.16 11.3 0.1 1.2 1 0 0 1 1 1 0 P-loop ATPase protein family adh_short PF00106.25 KXT04562.1 - 5.6e-53 179.3 1.6 6.7e-53 179.0 1.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT04562.1 - 2.9e-49 167.8 2.7 5.1e-49 166.9 2.7 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT04562.1 - 1e-12 48.4 0.3 1.8e-12 47.5 0.3 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXT04562.1 - 0.0018 17.8 0.2 0.0053 16.2 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ATP_bind_2 PF03668.15 KXT04562.1 - 0.095 12.0 0.1 0.16 11.3 0.1 1.2 1 0 0 1 1 1 0 P-loop ATPase protein family GTP_EFTU PF00009.27 KXT04563.1 - 4.9e-58 195.9 0.0 9.9e-58 194.9 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KXT04563.1 - 2e-13 50.2 0.0 5.8e-13 48.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KXT04563.1 - 2.5e-11 43.8 0.0 2.6e-10 40.5 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KXT04563.1 - 9.8e-08 32.0 0.0 2e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KXT04563.1 - 0.034 14.2 0.0 0.093 12.8 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase TBCA PF02970.16 KXT04563.1 - 0.043 14.2 1.2 0.16 12.3 1.2 2.0 1 0 0 1 1 1 0 Tubulin binding cofactor A EFG_IV PF03764.18 KXT04563.1 - 0.12 12.2 0.1 1 9.1 0.0 2.7 2 1 0 2 2 2 0 Elongation factor G, domain IV DUF4633 PF15464.6 KXT04563.1 - 0.86 9.8 6.7 1.1 9.5 1.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4633) adh_short PF00106.25 KXT04564.1 - 5.6e-53 179.3 1.6 6.7e-53 179.0 1.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT04564.1 - 2.9e-49 167.8 2.7 5.1e-49 166.9 2.7 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT04564.1 - 1e-12 48.4 0.3 1.8e-12 47.5 0.3 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXT04564.1 - 0.0018 17.8 0.2 0.0053 16.2 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ATP_bind_2 PF03668.15 KXT04564.1 - 0.095 12.0 0.1 0.16 11.3 0.1 1.2 1 0 0 1 1 1 0 P-loop ATPase protein family GTP_EFTU PF00009.27 KXT04565.1 - 4.3e-56 189.5 0.0 9.5e-56 188.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KXT04565.1 - 2e-13 50.2 0.0 5.9e-13 48.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KXT04565.1 - 2.6e-11 43.8 0.0 2.6e-10 40.5 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KXT04565.1 - 9.8e-08 32.0 0.0 2e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KXT04565.1 - 0.034 14.2 0.0 0.093 12.8 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase TBCA PF02970.16 KXT04565.1 - 0.043 14.1 1.2 0.16 12.3 1.2 2.0 1 0 0 1 1 1 0 Tubulin binding cofactor A EFG_IV PF03764.18 KXT04565.1 - 0.12 12.1 0.1 1 9.1 0.0 2.6 2 1 0 2 2 2 0 Elongation factor G, domain IV DUF4633 PF15464.6 KXT04565.1 - 0.87 9.7 6.7 1.1 9.4 1.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4633) Mis12 PF05859.12 KXT04566.1 - 5.2e-42 143.1 1.0 5.2e-42 143.1 1.0 1.6 2 0 0 2 2 2 1 Mis12 protein ALO PF04030.14 KXT04567.1 - 7.8e-85 284.8 0.8 1.3e-84 284.1 0.8 1.3 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 KXT04567.1 - 1.8e-26 92.6 0.0 2.8e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain adh_short PF00106.25 KXT04569.1 - 1.4e-22 80.2 0.0 3.3e-16 59.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXT04569.1 - 2.9e-15 56.5 0.0 1.9e-10 40.7 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT04569.1 - 0.00044 20.2 0.2 0.00084 19.3 0.2 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXT04569.1 - 0.1 11.7 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.25 KXT04570.1 - 1.9e-22 79.7 0.0 4.3e-16 59.0 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXT04570.1 - 4.2e-15 55.9 0.0 2.4e-10 40.4 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT04570.1 - 0.00051 20.0 0.2 0.001 19.0 0.2 1.5 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXT04570.1 - 0.12 11.4 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.25 KXT04571.1 - 1.9e-22 79.7 0.0 4.3e-16 59.0 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KXT04571.1 - 4.2e-15 55.9 0.0 2.4e-10 40.4 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT04571.1 - 0.00051 20.0 0.2 0.001 19.0 0.2 1.5 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXT04571.1 - 0.12 11.4 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein FTR1 PF03239.14 KXT04574.1 - 6.4e-90 301.4 6.0 7.6e-90 301.2 6.0 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family FAD_binding_4 PF01565.23 KXT04574.1 - 6.4e-05 22.7 0.4 0.0015 18.3 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain Herpes_glycop PF01528.16 KXT04574.1 - 0.039 12.8 0.3 0.77 8.5 0.1 2.5 2 0 0 2 2 2 0 Herpesvirus glycoprotein M DUF3021 PF11457.8 KXT04574.1 - 1 9.7 18.8 0.48 10.8 2.9 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3021) Zn_clus PF00172.18 KXT04575.1 - 0.00014 21.9 10.5 0.00027 21.0 10.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Trimer_CC PF08954.11 KXT04575.1 - 0.014 14.9 0.1 0.036 13.6 0.1 1.7 1 0 0 1 1 1 0 Trimerisation motif Zn_clus PF00172.18 KXT04577.1 - 1.8e-05 24.7 10.5 2.5e-05 24.3 10.5 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Trimer_CC PF08954.11 KXT04577.1 - 0.0019 17.7 0.1 0.0036 16.8 0.1 1.5 1 0 0 1 1 1 1 Trimerisation motif Enkurin PF13864.6 KXT04577.1 - 0.054 13.9 0.1 0.08 13.4 0.1 1.2 1 0 0 1 1 1 0 Calmodulin-binding Dickkopf_N PF04706.12 KXT04577.1 - 8.1 7.0 13.1 11 6.6 4.5 2.2 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region bZIP_1 PF00170.21 KXT04578.1 - 8.1e-11 41.9 8.6 1.7e-10 40.8 8.6 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXT04578.1 - 3.5e-09 36.6 9.2 3.5e-09 36.6 9.2 1.9 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 KXT04578.1 - 0.00037 21.0 8.9 0.00037 21.0 8.9 2.2 1 1 1 2 2 2 1 bZIP Maf transcription factor DUF4407 PF14362.6 KXT04578.1 - 0.6 9.4 11.9 0.82 9.0 11.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RPN2_C PF18004.1 KXT04578.1 - 3.5 7.5 12.4 6 6.8 12.4 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF3584 PF12128.8 KXT04578.1 - 3.7 5.0 14.9 4.7 4.6 14.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Ribosomal_L32e PF01655.18 KXT04579.1 - 2.8e-51 172.5 1.0 2.8e-51 172.5 1.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L32 DUF3431 PF11913.8 KXT04580.1 - 4.5e-05 23.3 0.1 0.00041 20.2 0.0 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF3431) FA_desaturase PF00487.24 KXT04580.1 - 0.038 13.8 10.8 4.5 7.0 2.7 3.2 3 0 0 3 3 3 0 Fatty acid desaturase Saf_2TM PF18303.1 KXT04580.1 - 0.16 11.5 3.3 0.26 10.9 0.5 2.5 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain PepSY_TM PF03929.16 KXT04580.1 - 2.8 7.5 8.8 0.53 9.9 2.4 2.8 2 2 1 3 3 3 0 PepSY-associated TM region FlpD PF02662.16 KXT04581.1 - 0.025 14.6 0.0 0.038 14.0 0.0 1.3 1 0 0 1 1 1 0 Methyl-viologen-reducing hydrogenase, delta subunit Peptidase_M24 PF00557.24 KXT04582.1 - 9.1e-09 35.3 0.0 1.4e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 GST_N PF02798.20 KXT04583.1 - 6.1e-16 58.5 0.0 1.3e-15 57.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXT04583.1 - 2e-15 56.9 0.0 3.1e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXT04583.1 - 9.9e-13 48.1 0.0 1.6e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KXT04583.1 - 2.2e-10 40.7 0.0 6.8e-10 39.1 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXT04583.1 - 3.9e-10 39.8 0.0 6.5e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KXT04583.1 - 1.3e-05 25.1 0.0 2.2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GFO_IDH_MocA PF01408.22 KXT04584.1 - 3.3e-19 69.9 0.0 5.6e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KXT04584.1 - 7.4e-08 32.4 0.0 2.5e-07 30.7 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 KXT04584.1 - 0.0023 18.6 0.0 0.0045 17.6 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.20 KXT04584.1 - 0.13 12.4 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus SDA1 PF05285.12 KXT04585.1 - 0.63 9.4 6.7 0.7 9.3 6.7 1.1 1 0 0 1 1 1 0 SDA1 YL1 PF05764.13 KXT04585.1 - 1.9 8.6 11.8 2.4 8.2 11.8 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Cwf_Cwc_15 PF04889.12 KXT04585.1 - 5.3 6.7 9.0 8.2 6.1 9.0 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 KXT04585.1 - 7.8 4.6 9.4 9.1 4.4 9.4 1.1 1 0 0 1 1 1 0 Nop14-like family Dus PF01207.17 KXT04587.1 - 8.3e-57 192.6 0.0 6.9e-56 189.6 0.0 2.2 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 KXT04587.1 - 0.093 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase VWA PF00092.28 KXT04589.1 - 3.7e-07 30.6 0.0 9.1e-07 29.3 0.0 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KXT04589.1 - 0.00019 22.0 0.0 0.00035 21.2 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain HLH PF00010.26 KXT04590.1 - 3.9e-12 45.9 0.4 7e-12 45.1 0.4 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain GIT1_C PF12205.8 KXT04590.1 - 0.028 14.5 2.3 0.088 12.9 2.3 1.7 1 1 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term DUF5333 PF17267.2 KXT04590.1 - 0.036 14.2 0.4 0.082 13.1 0.2 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF5333) Pox_A30L_A26L PF06086.12 KXT04590.1 - 0.041 13.6 0.1 0.058 13.1 0.1 1.1 1 0 0 1 1 1 0 Orthopoxvirus A26L/A30L protein PIF1 PF05970.14 KXT04591.1 - 7.1e-41 140.6 0.0 1.6e-28 100.0 0.0 2.6 2 1 1 3 3 3 2 PIF1-like helicase AAA_30 PF13604.6 KXT04591.1 - 7.4e-24 84.5 0.0 2.9e-22 79.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KXT04591.1 - 5.4e-10 39.8 0.0 2.3e-09 37.7 0.0 2.1 2 1 0 2 2 2 1 AAA domain Herpes_Helicase PF02689.14 KXT04591.1 - 3.9e-07 28.4 0.0 5e-06 24.8 0.0 2.1 2 0 0 2 2 2 1 Helicase Viral_helicase1 PF01443.18 KXT04591.1 - 2.1e-05 24.4 1.0 0.11 12.2 0.0 3.4 3 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 KXT04591.1 - 5.5e-05 22.9 0.1 0.00018 21.2 0.0 1.9 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 KXT04591.1 - 0.00062 20.1 0.1 0.0019 18.5 0.1 1.7 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 KXT04591.1 - 0.0022 17.9 1.4 2 8.3 0.2 2.4 2 0 0 2 2 2 2 NTPase T2SSE PF00437.20 KXT04591.1 - 0.0025 16.9 0.0 0.0039 16.3 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein MeaB PF03308.16 KXT04591.1 - 0.0035 16.4 0.6 0.0054 15.8 0.6 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_29 PF13555.6 KXT04591.1 - 0.006 16.3 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KXT04591.1 - 0.0077 16.6 0.1 0.03 14.7 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 KXT04591.1 - 0.0081 15.9 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 KXT04591.1 - 0.029 14.3 0.0 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase DEAD PF00270.29 KXT04591.1 - 0.032 14.0 0.8 1.1 9.0 0.8 2.2 1 1 0 1 1 1 0 DEAD/DEAH box helicase Helicase_RecD PF05127.14 KXT04591.1 - 0.053 13.4 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 Helicase TrwB_AAD_bind PF10412.9 KXT04591.1 - 0.14 11.1 0.1 0.24 10.2 0.1 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Trypsin PF00089.26 KXT04592.1 - 1.5e-10 41.2 0.0 2.4e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KXT04592.1 - 3.8e-06 27.9 0.0 7.6e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain F-box PF00646.33 KXT04593.1 - 2.8e-07 30.2 0.0 1.6e-06 27.9 0.0 2.3 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KXT04593.1 - 0.069 13.1 1.8 0.15 12.0 0.0 2.5 3 0 0 3 3 3 0 F-box-like Urm1 PF09138.11 KXT04594.1 - 7.7e-36 122.4 0.0 8.7e-36 122.2 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 KXT04594.1 - 0.0026 18.4 0.0 0.0034 18.0 0.0 1.2 1 0 0 1 1 1 1 ThiS family Rick_17kDa_Anti PF05433.15 KXT04596.1 - 0.00072 19.4 18.1 0.0013 18.6 18.1 1.4 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 KXT04596.1 - 0.0079 16.2 10.5 0.014 15.3 10.5 1.5 1 0 0 1 1 1 1 Glycine zipper DUF533 PF04391.12 KXT04596.1 - 0.049 13.2 0.5 0.071 12.7 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF533) ATPase_gene1 PF09527.10 KXT04596.1 - 1.7 8.8 4.7 2.9 8.1 4.7 1.3 1 0 0 1 1 1 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter TraT PF05818.12 KXT04596.1 - 1.9 8.1 5.5 2.8 7.5 5.5 1.1 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein DUF3455 PF11937.8 KXT04597.1 - 1.7e-41 142.2 0.2 2.3e-41 141.8 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2990 PF11693.8 KXT04597.1 - 0.016 15.4 0.0 0.07 13.3 0.0 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2990) TRAP_alpha PF03896.16 KXT04599.1 - 5.7e-09 35.6 0.2 3e-08 33.2 0.2 1.9 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit DUF4440 PF14534.6 KXT04601.1 - 0.019 15.3 0.1 0.063 13.7 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4440) Arb2 PF09757.9 KXT04602.1 - 4.4e-87 291.5 0.1 5.8e-87 291.1 0.1 1.2 1 0 0 1 1 1 1 Arb2 domain Hist_deacetyl PF00850.19 KXT04602.1 - 1.4e-82 277.7 0.3 2e-82 277.1 0.3 1.2 1 0 0 1 1 1 1 Histone deacetylase domain DUF3431 PF11913.8 KXT04602.1 - 0.065 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3431) NRDE-2 PF08424.10 KXT04603.1 - 7.1e-84 281.7 7.4 1.2e-83 280.9 2.3 2.2 2 0 0 2 2 2 2 NRDE-2, necessary for RNA interference SPT6_acidic PF14632.6 KXT04603.1 - 4.4 8.0 8.7 0.094 13.3 0.4 2.5 2 1 0 2 2 2 0 Acidic N-terminal SPT6 Sec2p PF06428.11 KXT04604.1 - 1.5e-13 50.5 12.6 1.5e-13 50.5 12.6 2.3 2 1 0 2 2 2 1 GDP/GTP exchange factor Sec2p Tup_N PF08581.10 KXT04604.1 - 0.0061 16.8 8.3 0.18 12.1 2.5 3.0 2 1 0 2 2 2 2 Tup N-terminal Tmemb_cc2 PF10267.9 KXT04604.1 - 0.0098 15.1 7.8 0.013 14.7 7.8 1.2 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein KIAA1430 PF13879.6 KXT04604.1 - 0.013 16.3 16.8 0.22 12.3 0.2 4.2 1 1 2 3 3 3 0 KIAA1430 homologue SlyX PF04102.12 KXT04604.1 - 0.055 14.1 21.7 0.088 13.4 1.2 4.3 2 2 2 4 4 4 0 SlyX UPF0242 PF06785.11 KXT04604.1 - 0.1 12.7 14.3 1.1 9.3 8.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus V_ATPase_I PF01496.19 KXT04604.1 - 0.31 8.9 5.6 0.55 8.1 5.6 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family BshC PF10079.9 KXT04604.1 - 0.6 8.8 11.6 0.13 11.0 8.2 1.5 2 0 0 2 2 2 0 Bacillithiol biosynthesis BshC RMI1_N PF08585.12 KXT04604.1 - 1.2 8.9 7.0 0.32 10.7 3.7 1.7 2 0 0 2 2 2 0 RecQ mediated genome instability protein BBP1_C PF15272.6 KXT04604.1 - 2 8.2 11.8 5.6 6.8 0.2 2.2 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal FlaC_arch PF05377.11 KXT04604.1 - 9.5 6.7 8.1 26 5.3 0.6 3.4 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) F-box PF00646.33 KXT04605.1 - 0.00021 21.1 0.0 0.0005 19.9 0.0 1.7 1 0 0 1 1 1 1 F-box domain ELFV_dehydrog_N PF02812.18 KXT04605.1 - 0.16 11.8 0.0 0.83 9.5 0.0 1.9 1 1 0 2 2 2 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain F-box PF00646.33 KXT04606.1 - 0.00021 21.1 0.0 0.0005 19.9 0.0 1.7 1 0 0 1 1 1 1 F-box domain ELFV_dehydrog_N PF02812.18 KXT04606.1 - 0.16 11.8 0.0 0.83 9.5 0.0 1.9 1 1 0 2 2 2 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain CLASP_N PF12348.8 KXT04607.1 - 1.7e-119 397.4 6.3 2.8e-84 282.2 0.8 3.2 3 0 0 3 3 3 2 CLASP N terminal HEAT PF02985.22 KXT04607.1 - 4.1e-05 23.5 1.5 0.091 13.1 0.0 5.1 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.7 KXT04607.1 - 0.0016 18.5 0.1 1.7 8.6 0.0 3.9 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Sec7_N PF12783.7 KXT04607.1 - 0.006 16.5 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF3361 PF11841.8 KXT04607.1 - 0.062 13.2 0.0 0.18 11.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3361) HEAT_EZ PF13513.6 KXT04607.1 - 0.08 13.5 0.2 3.7 8.2 0.1 3.4 2 0 0 2 2 2 0 HEAT-like repeat Adaptin_N PF01602.20 KXT04607.1 - 0.094 11.3 2.4 0.61 8.6 0.5 3.0 3 2 1 4 4 4 0 Adaptin N terminal region dsrm PF00035.26 KXT04608.1 - 7e-05 23.5 0.0 0.00022 21.8 0.0 1.9 2 0 0 2 2 2 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.6 KXT04608.1 - 0.00011 22.4 0.0 0.035 14.3 0.0 2.5 3 0 0 3 3 3 2 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KXT04608.1 - 0.025 15.2 0.2 0.46 11.1 0.1 2.5 2 1 0 2 2 2 0 Ribonuclease III domain Pyr_redox_3 PF13738.6 KXT04609.1 - 4.2e-16 59.1 1.5 4.6e-14 52.4 3.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KXT04609.1 - 2.9e-15 55.7 0.0 9.3e-15 54.0 0.0 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KXT04609.1 - 3.6e-12 46.1 0.2 5.4e-12 45.5 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXT04609.1 - 5.1e-10 39.0 0.2 8.2e-09 35.0 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KXT04609.1 - 2.3e-05 24.5 3.1 3.6e-05 23.9 0.4 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 KXT04609.1 - 8.6e-05 21.9 0.3 0.038 13.3 0.0 2.2 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KXT04609.1 - 0.00013 22.4 4.6 0.075 13.6 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KXT04609.1 - 0.0084 16.2 0.0 2.7 8.1 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 KXT04609.1 - 0.0098 15.5 4.2 0.0098 15.5 4.2 2.3 1 1 1 2 2 2 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 KXT04609.1 - 0.025 14.5 1.4 0.052 13.4 1.3 1.5 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 KXT04609.1 - 0.025 14.6 1.6 0.44 10.5 0.2 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding HMG_box PF00505.19 KXT04609.1 - 0.054 13.9 0.1 0.12 12.9 0.1 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box GATase_5 PF13507.6 KXT04609.1 - 0.077 12.1 0.1 0.14 11.2 0.1 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain NAD_binding_7 PF13241.6 KXT04609.1 - 0.17 12.4 0.0 0.83 10.1 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding HI0933_like PF03486.14 KXT04609.1 - 0.17 10.6 2.5 2 7.0 0.5 2.7 3 0 0 3 3 3 0 HI0933-like protein 2-Hacid_dh_C PF02826.19 KXT04609.1 - 0.18 11.2 0.3 14 5.0 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 KXT04609.1 - 3 6.8 6.2 0.81 8.7 1.8 1.9 2 0 0 2 2 2 0 FAD binding domain adh_short_C2 PF13561.6 KXT04610.1 - 3.7e-51 173.9 0.4 6.3e-51 173.2 0.4 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase SurE PF01975.17 KXT04610.1 - 6.2e-46 156.6 0.5 3.6e-45 154.1 0.1 2.0 2 0 0 2 2 2 1 Survival protein SurE adh_short PF00106.25 KXT04610.1 - 2e-43 148.1 1.5 3.4e-43 147.4 1.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXT04610.1 - 6.3e-13 49.0 0.5 1.3e-12 48.0 0.5 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXT04610.1 - 0.021 14.3 0.1 0.38 10.2 0.1 2.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Flavoprotein PF02441.19 KXT04610.1 - 0.099 12.4 0.0 0.96 9.2 0.0 2.2 2 0 0 2 2 2 0 Flavoprotein Caleosin PF05042.13 KXT04610.1 - 0.15 12.0 0.0 18 5.2 0.0 2.3 2 0 0 2 2 2 0 Caleosin related protein AdoHcyase_NAD PF00670.21 KXT04610.1 - 0.18 11.9 1.2 0.41 10.7 0.9 1.7 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Glyco_trans_4_2 PF13477.6 KXT04610.1 - 0.19 11.7 0.0 0.62 10.1 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase 4-like Cu-oxidase_2 PF07731.14 KXT04611.1 - 2.4e-48 163.3 9.5 4.9e-42 142.9 1.2 4.0 3 2 1 4 4 4 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KXT04611.1 - 3.3e-42 143.2 8.9 1.3e-39 134.9 1.3 4.4 5 0 0 5 5 5 2 Multicopper oxidase Cu-oxidase PF00394.22 KXT04611.1 - 2.1e-40 138.5 2.4 6.1e-35 120.7 0.2 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.6 KXT04611.1 - 0.0018 18.4 0.0 11 6.2 0.0 4.0 4 1 0 4 4 4 2 Cupredoxin-like domain DUF5060 PF16586.5 KXT04611.1 - 0.0041 17.5 0.7 0.091 13.1 0.1 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF5060) Cu-oxidase_2 PF07731.14 KXT04612.1 - 2.4e-48 163.3 9.5 4.9e-42 142.9 1.2 4.0 3 2 1 4 4 4 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KXT04612.1 - 3.3e-42 143.2 8.9 1.3e-39 134.9 1.3 4.4 5 0 0 5 5 5 2 Multicopper oxidase Cu-oxidase PF00394.22 KXT04612.1 - 2.1e-40 138.5 2.4 6.1e-35 120.7 0.2 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.6 KXT04612.1 - 0.0018 18.4 0.0 11 6.2 0.0 4.0 4 1 0 4 4 4 2 Cupredoxin-like domain DUF5060 PF16586.5 KXT04612.1 - 0.0041 17.5 0.7 0.091 13.1 0.1 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF5060) Cu-oxidase_2 PF07731.14 KXT04613.1 - 2.4e-48 163.3 9.5 4.9e-42 142.9 1.2 4.0 3 2 1 4 4 4 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KXT04613.1 - 3.3e-42 143.2 8.9 1.3e-39 134.9 1.3 4.4 5 0 0 5 5 5 2 Multicopper oxidase Cu-oxidase PF00394.22 KXT04613.1 - 2.1e-40 138.5 2.4 6.1e-35 120.7 0.2 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.6 KXT04613.1 - 0.0018 18.4 0.0 11 6.2 0.0 4.0 4 1 0 4 4 4 2 Cupredoxin-like domain DUF5060 PF16586.5 KXT04613.1 - 0.0041 17.5 0.7 0.091 13.1 0.1 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF5060) rRNA_processing PF08524.11 KXT04614.1 - 0.00069 19.7 32.0 0.00069 19.7 32.0 2.6 2 1 0 2 2 2 1 rRNA processing Ndc1_Nup PF09531.10 KXT04614.1 - 4.4 5.9 8.6 5.4 5.6 8.6 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4192 PF13830.6 KXT04614.1 - 4.8 7.1 7.2 5.7 6.9 7.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) AMP-binding PF00501.28 KXT04615.1 - 1.6e-65 221.4 1.6 7.8e-27 93.9 0.0 4.5 3 1 0 3 3 3 3 AMP-binding enzyme DMAP_binding PF06464.11 KXT04615.1 - 2.3e-12 47.7 0.1 2.3e-12 47.7 0.1 2.0 2 0 0 2 2 2 1 DMAP1-binding Domain GvpG PF05120.12 KXT04615.1 - 0.00039 20.4 0.3 0.00083 19.3 0.3 1.5 1 0 0 1 1 1 1 Gas vesicle protein G ACCA PF03255.14 KXT04616.1 - 0.05 13.5 0.2 0.18 11.7 0.1 2.0 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DMPK_coil PF08826.10 KXT04616.1 - 0.9 9.7 5.7 0.21 11.7 0.7 2.6 4 0 0 4 4 4 0 DMPK coiled coil domain like PS_Dcarbxylase PF02666.15 KXT04617.1 - 4.3e-78 261.5 0.0 2e-56 190.7 0.0 2.0 2 0 0 2 2 2 2 Phosphatidylserine decarboxylase NADH_oxidored PF08040.11 KXT04617.1 - 0.032 13.9 0.0 0.062 13.0 0.0 1.4 1 0 0 1 1 1 0 MNLL subunit RNA_capsid PF03035.14 KXT04617.1 - 6.6 6.7 5.7 5.1 7.1 3.8 1.7 2 0 0 2 2 2 0 Calicivirus putative RNA polymerase/capsid protein Sugar_tr PF00083.24 KXT04618.1 - 5.4e-78 262.9 23.7 6.2e-78 262.7 23.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXT04618.1 - 8.7e-22 77.5 34.5 8.4e-19 67.7 14.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXT04618.1 - 0.00057 18.6 4.5 0.00057 18.6 4.5 3.2 3 1 1 4 4 4 1 MFS/sugar transport protein CcmF_C PF16327.5 KXT04618.1 - 2.1 7.6 10.5 0.17 11.2 5.7 1.6 2 0 0 2 2 2 0 Cytochrome c-type biogenesis protein CcmF C-terminal eIF-6 PF01912.18 KXT04619.1 - 1.7e-80 269.0 0.5 2.7e-80 268.4 0.5 1.3 1 0 0 1 1 1 1 eIF-6 family Ferric_reduct PF01794.19 KXT04620.1 - 2.3e-22 79.4 6.7 8.6e-22 77.6 6.7 2.1 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KXT04620.1 - 1.6e-16 60.8 0.2 7.5e-14 52.1 0.2 2.4 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KXT04620.1 - 5.4e-09 36.1 0.0 0.00069 19.7 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.21 KXT04620.1 - 0.019 15.6 0.0 0.056 14.1 0.0 1.8 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain PetN PF03742.14 KXT04620.1 - 0.065 13.1 1.4 0.12 12.3 0.2 2.1 2 0 0 2 2 2 0 PetN DUF4405 PF14358.6 KXT04620.1 - 6.2 7.4 12.4 8.6 7.0 2.6 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) MFS_1 PF07690.16 KXT04621.1 - 6.9e-35 120.6 27.4 6.9e-35 120.6 27.4 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily TMIE PF16038.5 KXT04621.1 - 0.063 13.1 3.4 0.57 10.1 0.1 2.7 2 0 0 2 2 2 0 TMIE protein F-box PF00646.33 KXT04627.1 - 0.04 13.8 4.5 4 7.4 0.0 3.0 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.7 KXT04627.1 - 0.049 13.5 0.1 0.28 11.1 0.0 2.3 2 0 0 2 2 2 0 F-box-like Arrestin_C PF02752.22 KXT04628.1 - 3.9e-12 46.8 0.1 1.6e-11 44.8 0.1 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KXT04628.1 - 8.5e-08 32.4 0.0 4.8e-07 29.9 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 KXT04628.1 - 0.043 13.5 0.0 0.093 12.4 0.0 1.5 1 0 0 1 1 1 0 Arrestin_N terminal like COX17 PF05051.13 KXT04629.1 - 7.9e-22 77.4 5.7 9.7e-22 77.1 5.7 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) SH3-WW_linker PF16618.5 KXT04631.1 - 0.00041 20.9 8.4 0.00052 20.6 8.4 1.1 1 0 0 1 1 1 1 Linker region between SH3 and WW domains on ARHGAP12 DUF3504 PF12012.8 KXT04631.1 - 0.024 14.5 1.2 0.033 14.1 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3504) Vfa1 PF08432.10 KXT04631.1 - 0.036 14.4 10.0 0.044 14.1 10.0 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 XRCC4 PF06632.12 KXT04631.1 - 0.74 8.6 9.9 0.87 8.4 9.9 1.0 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 CDC45 PF02724.14 KXT04631.1 - 1.3 7.2 10.4 1.5 7.1 10.4 1.0 1 0 0 1 1 1 0 CDC45-like protein Spore_coat_CotO PF14153.6 KXT04631.1 - 4.5 7.1 11.4 5.7 6.8 11.4 1.2 1 0 0 1 1 1 0 Spore coat protein CotO NICE-3 PF07406.11 KXT04632.1 - 1.6 8.7 3.0 1.7 8.6 2.1 1.4 1 1 0 1 1 1 0 NICE-3 protein TraQ PF09679.10 KXT04633.1 - 0.0021 17.9 0.1 0.0021 17.9 0.1 1.9 2 0 0 2 2 2 1 Type-F conjugative transfer system pilin chaperone (TraQ) SKG6 PF08693.10 KXT04633.1 - 0.2 11.1 1.9 0.49 9.8 1.9 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF4776 PF16003.5 KXT04633.1 - 2.8 6.8 5.9 0.42 9.6 0.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4776) HSCB_C PF07743.13 KXT04634.1 - 3.9e-21 75.3 8.8 3.9e-21 75.3 8.8 2.3 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain dCMP_cyt_deam_1 PF00383.23 KXT04634.1 - 2e-14 53.3 0.3 3.6e-14 52.5 0.3 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 KXT04634.1 - 2.9e-10 40.5 5.3 2.4e-08 34.2 0.2 2.9 2 1 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region DnaJ PF00226.31 KXT04634.1 - 6.3e-07 29.4 0.6 1.6e-06 28.1 0.6 1.7 1 0 0 1 1 1 1 DnaJ domain ThiD2 PF17792.1 KXT04634.1 - 0.0023 18.4 2.4 0.0023 18.4 2.4 2.1 1 1 1 2 2 2 1 ThiD2 family LmjF365940-deam PF14421.6 KXT04634.1 - 0.0064 16.1 1.4 1.7 8.2 0.1 2.3 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases Asparaginase_2 PF01112.18 KXT04635.1 - 3.2e-53 180.7 0.2 4.1e-47 160.7 0.0 2.4 2 1 0 2 2 2 2 Asparaginase Mito_carr PF00153.27 KXT04636.1 - 7.6e-54 179.6 1.8 1.9e-18 66.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TAP35_44 PF07265.11 KXT04636.1 - 0.052 13.6 0.1 0.096 12.7 0.1 1.4 1 0 0 1 1 1 0 Tapetum specific protein TAP35/TAP44 Alanine_zipper PF11839.8 KXT04636.1 - 0.059 13.7 8.7 0.12 12.8 8.7 1.5 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein BLOC1_2 PF10046.9 KXT04639.1 - 0.002 18.4 0.2 0.0042 17.3 0.1 1.7 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3418 PF11898.8 KXT04639.1 - 0.0022 16.7 0.9 0.0032 16.2 0.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3418) Ntox27 PF15531.6 KXT04639.1 - 0.024 14.5 0.1 0.18 11.7 0.0 2.2 2 1 0 2 2 2 0 Bacterial toxin 27 Trypan_PARP PF05887.11 KXT04639.1 - 0.027 14.5 2.7 0.057 13.4 2.7 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Fib_alpha PF08702.10 KXT04639.1 - 0.042 14.0 2.1 0.12 12.5 0.4 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 KXT04639.1 - 0.19 12.2 0.8 6.7 7.2 0.1 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF16 PF01519.16 KXT04639.1 - 0.58 10.7 4.8 60 4.2 6.2 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 PHM7_cyt PF14703.6 KXT04639.1 - 0.65 10.2 4.5 0.17 12.1 0.4 2.0 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter zf-Nse PF11789.8 KXT04640.1 - 8.2e-21 73.6 0.5 1.4e-20 72.8 0.5 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 KXT04640.1 - 2.3e-05 24.3 0.0 8e-05 22.6 0.1 1.9 2 0 0 2 2 2 1 RING-type zinc-finger IFT57 PF10498.9 KXT04640.1 - 0.034 13.1 7.9 0.077 11.9 7.9 1.5 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 zf-C3HC4_2 PF13923.6 KXT04640.1 - 0.041 13.7 0.0 0.086 12.7 0.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.20 KXT04640.1 - 0.052 13.3 0.4 0.11 12.3 0.4 1.6 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger DUF3552 PF12072.8 KXT04640.1 - 0.053 12.9 11.9 0.09 12.2 11.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Fmp27_WPPW PF10359.9 KXT04640.1 - 0.063 12.1 5.0 0.097 11.5 5.0 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain CorA PF01544.18 KXT04640.1 - 0.091 12.1 4.4 0.14 11.4 4.4 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein V_ATPase_I PF01496.19 KXT04640.1 - 0.12 10.3 3.5 0.16 9.9 3.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ISG65-75 PF11727.8 KXT04640.1 - 0.14 11.3 4.1 0.23 10.7 4.1 1.3 1 0 0 1 1 1 0 Invariant surface glycoprotein DUF1043 PF06295.12 KXT04640.1 - 0.31 11.0 3.6 0.67 10.0 2.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) DUF16 PF01519.16 KXT04640.1 - 0.43 11.1 4.8 0.24 11.9 2.0 2.0 2 0 0 2 2 1 0 Protein of unknown function DUF16 Uds1 PF15456.6 KXT04640.1 - 0.54 10.4 8.6 1.2 9.3 8.0 2.0 2 0 0 2 2 1 0 Up-regulated During Septation DUF1664 PF07889.12 KXT04640.1 - 0.93 9.5 3.1 1.3 9.1 2.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) UPF0242 PF06785.11 KXT04640.1 - 1 9.4 5.0 1.8 8.6 5.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus OmpH PF03938.14 KXT04640.1 - 1.6 9.0 12.9 0.32 11.3 8.0 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Muted PF14942.6 KXT04640.1 - 1.8 8.9 10.5 0.32 11.3 6.7 1.6 2 0 0 2 2 1 0 Organelle biogenesis, Muted-like protein Atg14 PF10186.9 KXT04640.1 - 2.5 7.1 8.0 4.3 6.3 8.0 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 COG2 PF06148.11 KXT04640.1 - 2.6 8.1 5.5 2.8 8.0 2.5 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 HEAT_EZ PF13513.6 KXT04641.1 - 4.1e-20 71.9 7.6 3.2e-06 27.5 0.2 7.6 7 2 2 9 9 8 4 HEAT-like repeat HEAT PF02985.22 KXT04641.1 - 4.5e-19 66.9 10.1 0.00024 21.1 0.2 9.9 12 0 0 12 12 8 3 HEAT repeat HEAT_2 PF13646.6 KXT04641.1 - 3.6e-18 65.7 10.3 0.00079 19.8 0.1 8.5 7 2 2 9 9 8 5 HEAT repeats IBN_N PF03810.19 KXT04641.1 - 2.2e-11 43.5 4.5 8.7e-11 41.6 0.8 3.5 4 0 0 4 4 4 1 Importin-beta N-terminal domain UME PF08064.13 KXT04641.1 - 1.1e-10 41.4 1.2 0.003 17.5 0.2 5.8 5 1 1 6 6 6 2 UME (NUC010) domain RIX1 PF08167.12 KXT04641.1 - 1.6e-10 41.0 0.1 0.037 13.8 0.7 5.0 3 1 0 4 4 4 3 rRNA processing/ribosome biogenesis Vac14_Fab1_bd PF12755.7 KXT04641.1 - 8.5e-09 35.9 0.1 0.6 10.7 0.0 5.9 6 1 1 7 7 7 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KXT04641.1 - 2.9e-08 33.9 6.5 0.52 10.4 0.0 5.6 4 1 1 6 6 6 3 non-SMC mitotic condensation complex subunit 1 IFRD PF05004.13 KXT04641.1 - 2.9e-07 29.9 13.9 2.6e-05 23.5 0.6 4.6 3 1 1 4 4 4 2 Interferon-related developmental regulator (IFRD) RTP1_C1 PF10363.9 KXT04641.1 - 2.8e-06 27.5 2.8 1 9.6 0.1 5.9 3 2 2 5 5 5 2 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 KXT04641.1 - 3.5e-06 26.9 2.0 0.32 11.1 0.0 6.3 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat Ecm29 PF13001.7 KXT04641.1 - 0.00036 19.3 9.6 0.021 13.5 2.0 4.6 3 2 3 6 6 6 1 Proteasome stabiliser ParcG PF10274.9 KXT04641.1 - 0.0014 18.8 1.4 1.5 8.9 0.1 3.6 3 0 0 3 3 3 1 Parkin co-regulated protein NUC173 PF08161.12 KXT04641.1 - 0.0046 16.6 1.6 9 5.9 0.0 4.7 3 1 1 4 4 4 1 NUC173 domain MMS19_C PF12460.8 KXT04641.1 - 0.0059 15.8 0.0 0.0059 15.8 0.0 5.4 6 0 0 6 6 6 1 RNAPII transcription regulator C-terminal Cohesin_HEAT PF12765.7 KXT04641.1 - 0.028 14.7 0.2 7.6 6.9 0.0 3.0 3 0 0 3 3 2 0 HEAT repeat associated with sister chromatid cohesion Tti2 PF10521.9 KXT04641.1 - 0.075 12.6 1.6 1.6 8.2 0.0 3.3 3 1 0 3 3 3 0 Tti2 family LuxT_C PF18285.1 KXT04641.1 - 0.15 12.6 1.8 4.4 7.9 0.2 3.6 3 0 0 3 3 3 0 Tetracycline repressor LuxT C-terminal domain DUF4211 PF13926.6 KXT04641.1 - 1.6 8.8 3.5 3.1 7.8 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4211) DUF4405 PF14358.6 KXT04642.1 - 0.017 15.6 0.4 0.021 15.4 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4405) Synaphin PF05835.12 KXT04643.1 - 0.017 15.4 1.9 0.031 14.5 1.9 1.3 1 0 0 1 1 1 0 Synaphin protein DUF3584 PF12128.8 KXT04643.1 - 0.034 11.7 1.9 0.042 11.4 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF812 PF05667.11 KXT04643.1 - 0.12 11.2 5.0 0.19 10.6 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Ysc84 PF04366.12 KXT04645.1 - 3.8e-40 136.6 0.2 6.7e-40 135.8 0.2 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 KXT04645.1 - 1.4e-13 50.3 0.2 4.2e-13 48.7 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KXT04645.1 - 1.8e-13 49.9 0.2 7.3e-13 48.0 0.1 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 KXT04645.1 - 2.7e-10 40.0 0.0 2.7e-10 40.0 0.0 2.1 3 0 0 3 3 3 1 Variant SH3 domain LMBR1 PF04791.16 KXT04646.1 - 1.6e-111 373.8 5.1 1.9e-111 373.5 5.1 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein DUF594 PF04578.13 KXT04646.1 - 0.11 12.1 0.1 0.28 10.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF594 Matrilin_ccoil PF10393.9 KXT04646.1 - 0.11 12.3 0.6 0.29 11.0 0.1 1.9 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin HECT PF00632.25 KXT04647.1 - 3.8e-76 256.5 0.0 5.9e-76 255.9 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.23 KXT04647.1 - 0.0021 18.1 9.8 3.4 7.8 0.1 6.7 7 1 1 8 8 8 1 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KXT04647.1 - 0.015 15.5 0.2 3.2 8.2 0.1 3.4 2 0 0 2 2 2 0 HEAT repeat HEAT_EZ PF13513.6 KXT04647.1 - 0.097 13.2 0.0 2.7 8.6 0.0 3.2 2 0 0 2 2 2 0 HEAT-like repeat Adaptin_N PF01602.20 KXT04647.1 - 0.31 9.5 7.9 0.15 10.5 0.2 3.2 3 1 1 4 4 4 0 Adaptin N terminal region CLASP_N PF12348.8 KXT04647.1 - 0.33 10.5 2.6 1 8.9 0.1 2.8 3 0 0 3 3 3 0 CLASP N terminal DUF2992 PF11208.8 KXT04647.1 - 1.2 9.4 3.4 3.3 8.0 3.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) HECT PF00632.25 KXT04649.1 - 3.8e-76 256.5 0.0 5.9e-76 255.9 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.23 KXT04649.1 - 0.0022 18.0 9.8 3.4 7.8 0.1 6.7 7 1 1 8 8 8 1 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KXT04649.1 - 0.015 15.5 0.2 3.2 8.2 0.1 3.4 2 0 0 2 2 2 0 HEAT repeat HEAT_EZ PF13513.6 KXT04649.1 - 0.099 13.2 0.0 2.7 8.6 0.0 3.2 2 0 0 2 2 2 0 HEAT-like repeat Adaptin_N PF01602.20 KXT04649.1 - 0.3 9.6 7.8 0.15 10.6 0.2 3.2 3 1 1 4 4 4 0 Adaptin N terminal region CLASP_N PF12348.8 KXT04649.1 - 0.34 10.4 2.6 1 8.9 0.1 2.8 3 0 0 3 3 3 0 CLASP N terminal DUF2992 PF11208.8 KXT04649.1 - 1.1 9.5 3.4 3.3 8.0 3.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) ICL PF00463.21 KXT04650.1 - 5.1e-196 652.2 0.2 5.9e-196 652.0 0.2 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 KXT04650.1 - 1.3e-10 41.1 0.1 5.6e-10 39.1 0.0 2.0 3 0 0 3 3 3 1 Phosphoenolpyruvate phosphomutase Peptidase_S28 PF05577.12 KXT04651.1 - 1.4e-47 162.5 0.5 5.2e-47 160.6 0.4 1.9 2 1 0 2 2 2 1 Serine carboxypeptidase S28 PTPA PF03095.15 KXT04653.1 - 9.1e-117 389.8 0.0 1.1e-116 389.6 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Smr PF01713.21 KXT04654.1 - 1.3e-05 25.5 0.1 2.9e-05 24.3 0.1 1.6 1 0 0 1 1 1 1 Smr domain Isochorismatase PF00857.20 KXT04656.1 - 1.8e-34 119.4 0.0 2.1e-34 119.2 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family Isochorismatase PF00857.20 KXT04657.1 - 1.8e-34 119.4 0.0 2.1e-34 119.2 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family PEX11 PF05648.14 KXT04659.1 - 3.3e-71 239.3 0.8 3.8e-71 239.1 0.8 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Isochorismatase PF00857.20 KXT04660.1 - 1.8e-34 119.4 0.0 2.1e-34 119.2 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family TPR_MLP1_2 PF07926.12 KXT04661.1 - 0.0046 17.0 14.8 0.0046 17.0 14.8 7.2 3 3 4 7 7 7 3 TPR/MLP1/MLP2-like protein Nbl1_Borealin_N PF10444.9 KXT04661.1 - 2.9 7.6 5.9 2.2 8.0 0.1 4.0 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal AMP-binding PF00501.28 KXT04662.1 - 2.4e-46 158.2 0.0 3.6e-46 157.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KXT04662.1 - 1.8e-06 27.7 0.0 5.4e-06 26.2 0.0 1.9 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KXT04662.1 - 0.006 17.5 0.0 0.052 14.5 0.0 2.5 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 KXT04663.1 - 4.5e-29 101.5 28.0 4.5e-29 101.5 28.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FtsJ PF01728.19 KXT04664.1 - 5.5e-61 205.8 0.0 8.1e-61 205.2 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase MFS_1 PF07690.16 KXT04664.1 - 1e-09 37.8 47.5 6.6e-09 35.1 41.8 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily QCR10 PF09796.9 KXT04664.1 - 0.14 12.3 0.1 0.14 12.3 0.1 2.8 3 0 0 3 3 3 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Citrate_synt PF00285.21 KXT04665.1 - 4.7e-99 331.9 0.0 5.7e-99 331.6 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain zf-RING_2 PF13639.6 KXT04666.1 - 2.2e-09 37.5 3.4 3.3e-09 36.9 3.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KXT04666.1 - 2.1e-06 27.9 4.0 7.5e-06 26.1 4.0 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KXT04666.1 - 0.00027 20.9 6.6 0.00045 20.2 6.6 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KXT04666.1 - 0.00073 19.5 0.8 0.0012 18.9 0.8 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 KXT04666.1 - 0.0052 16.6 5.5 0.011 15.5 5.3 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXT04666.1 - 0.014 15.3 2.5 0.023 14.5 2.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXT04666.1 - 0.016 15.0 1.3 0.064 13.1 1.3 1.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXT04666.1 - 0.025 14.3 3.4 0.041 13.6 3.4 1.4 1 0 0 1 1 1 0 RING-like zinc finger zinc_ribbon_9 PF14369.6 KXT04666.1 - 0.045 14.0 0.1 0.12 12.6 0.1 1.7 1 0 0 1 1 1 0 zinc-ribbon Prok-RING_4 PF14447.6 KXT04666.1 - 0.067 13.1 5.6 0.43 10.5 0.3 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 PUL PF08324.11 KXT04666.1 - 0.072 12.3 0.1 0.096 11.9 0.1 1.2 1 0 0 1 1 1 0 PUL domain FAD_binding_1 PF00667.20 KXT04667.1 - 4.2e-59 199.8 0.0 6.6e-59 199.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KXT04667.1 - 3.6e-09 37.2 0.0 1.3e-08 35.5 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.18 KXT04667.1 - 4.7e-07 30.1 0.0 1.1e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase PFOR_II PF17147.4 KXT04667.1 - 4.4e-06 26.9 0.1 1.2e-05 25.6 0.1 1.7 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Transketolase_C PF02780.20 KXT04667.1 - 0.0032 17.4 0.2 0.01 15.7 0.2 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain FAD_binding_6 PF00970.24 KXT04667.1 - 0.077 13.4 0.0 2.3 8.6 0.0 2.8 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain Gpi16 PF04113.14 KXT04668.1 - 1.3e-213 710.5 0.0 2e-213 709.9 0.0 1.1 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Inositol_P PF00459.25 KXT04668.1 - 3.3e-50 171.1 0.5 8.7e-50 169.7 0.5 1.6 1 1 0 1 1 1 1 Inositol monophosphatase family Sec3_C PF09763.9 KXT04669.1 - 1.1e-192 642.2 0.0 1.4e-192 641.9 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 KXT04669.1 - 2.3e-27 94.9 0.0 4.2e-27 94.1 0.0 1.4 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH End3 PF12761.7 KXT04669.1 - 0.00057 20.1 1.4 0.0013 18.9 1.4 1.6 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 Vps52 PF04129.12 KXT04669.1 - 0.0012 17.7 0.2 0.0012 17.7 0.2 1.5 2 0 0 2 2 2 1 Vps52 / Sac2 family Sec3_C_2 PF15278.6 KXT04669.1 - 0.035 14.5 0.0 0.11 12.8 0.0 1.8 1 0 0 1 1 1 0 Sec3 exocyst complex subunit Dict-STAT-coil PF09267.10 KXT04669.1 - 4.5 7.7 6.3 29 5.1 0.4 2.6 2 0 0 2 2 2 0 Dictyostelium STAT, coiled coil Gemini_AL2 PF01440.16 KXT04669.1 - 5.4 7.5 7.7 8.9 6.8 0.8 2.8 2 0 0 2 2 2 0 Geminivirus AL2 protein adh_short_C2 PF13561.6 KXT04670.1 - 1.6e-31 109.7 0.0 4.6e-31 108.2 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXT04670.1 - 4.5e-25 88.2 0.0 7.2e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXT04670.1 - 0.00011 22.2 0.0 0.0003 20.7 0.0 1.6 2 0 0 2 2 2 1 KR domain Beta-lactamase PF00144.24 KXT04671.1 - 1.2e-37 129.9 0.0 1.8e-37 129.4 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Transket_pyr PF02779.24 KXT04672.1 - 4.5e-45 153.5 0.1 7.1e-45 152.9 0.1 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KXT04672.1 - 5.9e-32 110.2 0.0 2.3e-31 108.3 0.0 2.0 2 0 0 2 2 2 1 Transketolase, C-terminal domain PFOR_II PF17147.4 KXT04672.1 - 0.006 16.9 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Prenyltransf PF01255.19 KXT04672.1 - 0.0096 15.5 0.0 0.023 14.2 0.0 1.6 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Con-6 PF10346.9 KXT04672.1 - 0.053 13.6 0.3 0.11 12.6 0.3 1.5 1 0 0 1 1 1 0 Conidiation protein 6 His_Phos_2 PF00328.22 KXT04673.1 - 4.7e-36 125.0 0.0 6.7e-36 124.4 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RmlD_sub_bind PF04321.17 KXT04674.1 - 0.052 12.7 0.0 0.11 11.6 0.0 1.5 2 0 0 2 2 2 0 RmlD substrate binding domain ABC2_membrane PF01061.24 KXT04675.1 - 4.4e-30 104.7 27.0 6.8e-30 104.1 27.0 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KXT04675.1 - 5.5e-26 91.7 0.0 9e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KXT04675.1 - 7e-06 26.1 0.2 4.8e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 KXT04675.1 - 3e-05 24.0 0.3 0.23 11.2 0.0 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KXT04675.1 - 0.0005 19.7 0.0 0.0011 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KXT04675.1 - 0.0007 19.9 0.0 0.0025 18.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 KXT04675.1 - 0.00075 19.0 0.1 0.0032 16.9 0.1 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KXT04675.1 - 0.00078 19.9 0.1 0.0014 19.0 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KXT04675.1 - 0.0019 17.9 0.0 0.0048 16.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KXT04675.1 - 0.023 14.8 0.1 0.062 13.4 0.1 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_13 PF13166.6 KXT04675.1 - 0.026 13.2 1.6 0.28 9.8 0.1 2.7 3 0 0 3 3 3 0 AAA domain T2SSE PF00437.20 KXT04675.1 - 0.049 12.7 0.1 0.081 12.0 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.6 KXT04675.1 - 0.051 14.1 0.0 0.12 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KXT04675.1 - 0.053 13.5 0.0 0.17 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 KXT04675.1 - 0.053 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_14 PF13173.6 KXT04675.1 - 0.063 13.3 0.0 0.16 12.0 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.6 KXT04675.1 - 0.066 13.5 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KXT04675.1 - 0.08 13.1 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KXT04675.1 - 0.082 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KXT04675.1 - 0.099 13.1 0.1 0.35 11.3 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KXT04675.1 - 0.1 13.0 0.0 0.29 11.5 0.0 1.8 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 KXT04675.1 - 0.12 12.1 0.1 0.69 9.6 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein Cytidylate_kin PF02224.18 KXT04675.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase ATPase_2 PF01637.18 KXT04675.1 - 0.19 11.6 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF423 PF04241.15 KXT04675.1 - 0.78 10.0 6.3 8.6 6.6 0.5 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF423) RRM_1 PF00076.22 KXT04676.1 - 8.4e-46 153.7 0.0 1.4e-23 82.5 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KXT04676.1 - 5.6e-05 23.1 0.1 0.096 12.7 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KXT04676.1 - 0.00068 19.5 0.0 0.11 12.3 0.0 2.5 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_7 PF16367.5 KXT04676.1 - 0.011 15.8 0.0 4.5 7.5 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif AAR2 PF05282.11 KXT04677.1 - 0.092 12.1 4.5 0.15 11.4 1.2 2.1 2 0 0 2 2 2 0 AAR2 protein DUF5383 PF17355.2 KXT04677.1 - 0.41 11.0 1.7 0.68 10.3 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5383) EOS1 PF12326.8 KXT04677.1 - 0.63 10.0 2.6 3.6 7.5 2.6 2.0 1 1 0 1 1 1 0 N-glycosylation protein RRM_1 PF00076.22 KXT04678.1 - 8.1e-46 153.7 0.0 1.3e-23 82.5 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KXT04678.1 - 5.5e-05 23.1 0.1 0.094 12.7 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KXT04678.1 - 0.00065 19.5 0.0 0.11 12.3 0.0 2.5 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_7 PF16367.5 KXT04678.1 - 0.011 15.9 0.0 4.4 7.5 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif Sec10 PF07393.11 KXT04679.1 - 2.2e-207 690.8 0.0 3.1e-207 690.3 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 DUF489 PF04356.12 KXT04679.1 - 0.11 12.5 0.9 0.46 10.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF489) Spore_III_AB PF09548.10 KXT04679.1 - 0.51 10.4 3.5 8.8 6.4 0.0 3.4 3 1 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) Exonuc_VII_L PF02601.15 KXT04679.1 - 0.72 9.4 4.2 0.84 9.1 0.1 2.5 3 0 0 3 3 3 0 Exonuclease VII, large subunit Rick_17kDa_Anti PF05433.15 KXT04680.1 - 0.00048 19.9 7.5 0.00077 19.3 7.5 1.3 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 KXT04680.1 - 0.0036 17.3 5.3 0.0066 16.4 5.3 1.4 1 0 0 1 1 1 1 Glycine zipper DUF456 PF04306.13 KXT04680.1 - 0.087 13.1 0.1 0.12 12.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Gly-zipper_YMGG PF13441.6 KXT04680.1 - 0.55 10.0 11.9 1 9.1 11.9 1.3 1 0 0 1 1 1 0 YMGG-like Gly-zipper Bacteriocin_IIc PF10439.9 KXT04680.1 - 1.6 8.9 7.8 2.7 8.2 7.8 1.2 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide SDP_N PF12278.8 KXT04680.1 - 7.6 6.7 7.7 0.55 10.4 2.2 1.7 2 0 0 2 2 2 0 Sex determination protein N terminal Spc7 PF08317.11 KXT04681.1 - 0.0038 16.2 8.7 0.024 13.5 1.0 2.6 3 0 0 3 3 3 2 Spc7 kinetochore protein FXMR_C2 PF16098.5 KXT04681.1 - 0.031 14.7 0.6 0.096 13.2 0.6 1.8 1 0 0 1 1 1 0 Fragile X-related mental retardation protein C-terminal region 2 DUF1043 PF06295.12 KXT04681.1 - 0.042 13.8 5.3 0.19 11.8 0.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1043) PknH_C PF14032.6 KXT04681.1 - 0.052 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 PknH-like extracellular domain DUF5347 PF17282.2 KXT04681.1 - 0.068 13.5 0.3 0.27 11.6 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5347) Snapin_Pallidin PF14712.6 KXT04681.1 - 0.11 12.9 12.1 0.84 10.1 1.3 4.5 3 1 1 4 4 4 0 Snapin/Pallidin FUSC PF04632.12 KXT04681.1 - 0.11 11.0 15.1 0.93 7.9 7.3 2.1 1 1 1 2 2 2 0 Fusaric acid resistance protein family AAA_13 PF13166.6 KXT04681.1 - 0.17 10.5 5.7 1.5 7.4 5.7 2.0 1 1 0 1 1 1 0 AAA domain Trimer_CC PF08954.11 KXT04681.1 - 0.18 11.4 4.0 4.4 6.9 0.7 4.3 4 0 0 4 4 4 0 Trimerisation motif UDPGT PF00201.18 KXT04681.1 - 0.2 10.4 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Tup_N PF08581.10 KXT04681.1 - 0.23 11.8 5.1 0.35 11.2 0.2 3.1 3 0 0 3 3 3 0 Tup N-terminal Syntaxin-6_N PF09177.11 KXT04681.1 - 0.24 12.0 6.3 0.42 11.2 0.7 2.9 2 1 1 3 3 3 0 Syntaxin 6, N-terminal DUF4407 PF14362.6 KXT04681.1 - 0.33 10.3 11.5 46 3.2 11.5 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ECH_2 PF16113.5 KXT04681.1 - 0.86 9.0 6.3 0.46 9.9 1.7 2.0 1 1 1 2 2 2 0 Enoyl-CoA hydratase/isomerase Atg14 PF10186.9 KXT04681.1 - 1.3 8.1 10.7 0.32 10.0 1.1 2.3 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Cob_adeno_trans PF01923.18 KXT04681.1 - 2.2 8.4 5.7 5.5 7.1 1.4 2.7 1 1 1 2 2 2 0 Cobalamin adenosyltransferase DUF2203 PF09969.9 KXT04681.1 - 3.2 8.5 8.4 28 5.5 0.4 3.4 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) THOC7 PF05615.13 KXT04681.1 - 4.4 7.6 11.4 5.2 7.3 2.0 2.7 2 1 0 2 2 2 0 Tho complex subunit 7 ParA PF10609.9 KXT04682.1 - 6e-96 320.6 0.1 6.7e-96 320.5 0.1 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KXT04682.1 - 1.2e-13 51.2 0.0 1.6e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KXT04682.1 - 4e-08 33.4 1.2 1.2e-07 31.8 1.2 1.9 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 KXT04682.1 - 4.1e-06 26.2 0.6 0.00023 20.5 0.1 2.7 2 1 1 3 3 3 1 Anion-transporting ATPase MipZ PF09140.11 KXT04682.1 - 4.5e-06 26.1 0.3 8.9e-06 25.2 0.3 1.6 1 1 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.18 KXT04682.1 - 8.5e-06 25.4 0.0 0.04 13.4 0.0 2.2 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.6 KXT04682.1 - 0.00092 18.8 0.1 0.0016 18.0 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_26 PF13500.6 KXT04682.1 - 0.015 15.1 0.4 3.3 7.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain FTHFS PF01268.19 KXT04682.1 - 0.057 11.6 0.1 0.13 10.4 0.1 1.5 2 0 0 2 2 2 0 Formate--tetrahydrofolate ligase CLP1_P PF16575.5 KXT04682.1 - 0.17 11.6 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop LUC7 PF03194.15 KXT04683.1 - 3.1e-72 243.3 6.8 3.6e-72 243.1 6.8 1.0 1 0 0 1 1 1 1 LUC7 N_terminus zinc_ribbon_16 PF17034.5 KXT04683.1 - 0.042 14.1 0.0 0.088 13.0 0.0 1.4 1 0 0 1 1 1 0 Zinc-ribbon like family MCPsignal PF00015.21 KXT04683.1 - 0.062 13.1 0.1 0.099 12.4 0.1 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain GRP PF07172.11 KXT04683.1 - 2.2 9.0 31.2 0.61 10.8 27.4 1.9 2 0 0 2 2 2 0 Glycine rich protein family UAA PF08449.11 KXT04684.1 - 2.6e-42 145.1 17.5 5.5e-41 140.7 17.5 2.2 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 KXT04684.1 - 7.3e-08 32.7 24.7 6.6e-05 23.1 5.9 4.0 4 1 1 5 5 5 2 EamA-like transporter family Nuc_sug_transp PF04142.15 KXT04684.1 - 5.1e-06 25.9 3.0 0.0044 16.2 0.2 2.3 2 0 0 2 2 2 2 Nucleotide-sugar transporter Multi_Drug_Res PF00893.19 KXT04684.1 - 0.041 14.5 2.0 0.15 12.8 0.2 2.9 3 0 0 3 3 3 0 Small Multidrug Resistance protein ArfGap PF01412.18 KXT04686.1 - 4.6e-39 133.1 3.2 6.7e-39 132.6 3.2 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf MFS_1 PF07690.16 KXT04687.1 - 4.4e-21 75.2 32.5 2.3e-10 40.0 6.6 3.3 3 0 0 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.6 KXT04687.1 - 7.1e-09 34.7 15.3 5.1e-07 28.6 2.1 4.0 4 0 0 4 4 4 3 MFS/sugar transport protein ATG22 PF11700.8 KXT04687.1 - 4.3e-07 28.9 3.9 0.00029 19.6 0.0 3.2 2 1 1 3 3 3 2 Vacuole effluxer Atg22 like Phage_holin_3_6 PF07332.11 KXT04687.1 - 0.017 15.1 0.4 0.017 15.1 0.4 5.0 4 2 0 4 4 4 0 Putative Actinobacterial Holin-X, holin superfamily III BT1 PF03092.16 KXT04687.1 - 1.6 6.8 9.7 1.7 6.8 0.9 3.4 3 1 1 4 4 4 0 BT1 family FAD_binding_7 PF03441.14 KXT04688.1 - 1.7e-75 253.0 0.4 2.6e-75 252.4 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KXT04688.1 - 4.3e-37 127.7 0.0 7e-37 127.0 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase GTP_EFTU PF00009.27 KXT04689.1 - 3e-46 157.4 0.0 5.8e-46 156.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 KXT04689.1 - 1.3e-20 73.5 0.9 3e-20 72.3 0.9 1.6 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D3 PF03143.17 KXT04689.1 - 5.3e-08 33.1 0.0 1.1e-07 32.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 KXT04689.1 - 1.1e-06 28.6 0.0 0.00014 21.9 0.0 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KXT04689.1 - 0.0057 16.1 0.0 0.22 11.0 0.0 2.4 1 1 1 2 2 2 1 ADP-ribosylation factor family GTP_EFTU_D2 PF03144.25 KXT04689.1 - 0.0079 16.6 0.1 0.039 14.3 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Roc PF08477.13 KXT04689.1 - 0.008 16.4 0.0 1.3 9.3 0.0 2.7 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 KXT04689.1 - 0.067 12.7 0.2 1.5 8.3 0.1 2.8 2 1 0 2 2 2 0 Ferrous iron transport protein B TraE PF05309.11 KXT04689.1 - 0.13 11.6 0.2 0.33 10.3 0.2 1.6 1 0 0 1 1 1 0 TraE protein SRPRB PF09439.10 KXT04689.1 - 0.56 9.6 3.8 2 7.8 0.1 2.7 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit DUF4594 PF15266.6 KXT04689.1 - 0.69 10.2 8.0 1.2 9.5 8.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4594) GTP_EFTU PF00009.27 KXT04690.1 - 6.9e-46 156.2 0.0 1.2e-45 155.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 KXT04690.1 - 2.1e-20 72.8 0.9 4.8e-20 71.7 0.9 1.6 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D3 PF03143.17 KXT04690.1 - 9.5e-08 32.3 0.0 1.8e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 KXT04690.1 - 2.3e-06 27.6 0.0 0.00025 21.1 0.0 2.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KXT04690.1 - 0.016 14.7 0.0 0.43 10.0 0.0 2.3 1 1 1 2 2 2 0 ADP-ribosylation factor family GTP_EFTU_D2 PF03144.25 KXT04690.1 - 0.017 15.5 0.0 0.062 13.7 0.0 2.0 1 0 0 1 1 1 0 Elongation factor Tu domain 2 Roc PF08477.13 KXT04690.1 - 0.024 14.9 0.0 2.1 8.6 0.0 2.6 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KXT04690.1 - 0.13 11.7 0.1 3.3 7.1 0.1 2.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 KXT04690.1 - 0.18 11.3 0.2 2.3 7.7 0.1 2.6 2 1 0 2 2 2 0 Ferrous iron transport protein B Fe-ADH PF00465.19 KXT04691.1 - 6.8e-102 341.0 0.0 8.6e-102 340.6 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KXT04691.1 - 2.2e-13 50.5 0.0 8.7e-10 38.7 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Methyltransf_23 PF13489.6 KXT04694.1 - 3.3e-11 43.3 0.0 5.1e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXT04694.1 - 1.3e-09 38.6 0.0 3.9e-09 37.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXT04694.1 - 2.8e-06 28.0 0.0 9.3e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXT04694.1 - 1.9e-05 25.2 0.0 7.6e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXT04694.1 - 5.4e-05 23.0 0.0 0.00011 22.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXT04694.1 - 0.044 13.1 0.0 0.096 12.0 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF515 PF04415.12 KXT04695.1 - 1.2 7.4 3.8 1.4 7.2 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DNA_binding_1 PF01035.20 KXT04696.1 - 5.8e-27 93.6 0.0 7.4e-27 93.3 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain ADH_zinc_N PF00107.26 KXT04699.1 - 1.9e-27 95.8 0.1 2.9e-27 95.2 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXT04699.1 - 1.6e-23 84.2 0.0 2.6e-23 83.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXT04699.1 - 0.00017 21.4 0.1 0.00054 19.8 0.1 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Peripla_BP_6 PF13458.6 KXT04699.1 - 0.00087 19.0 0.3 0.0019 17.9 0.2 1.5 1 1 0 1 1 1 1 Periplasmic binding protein ADH_N_2 PF16884.5 KXT04699.1 - 0.014 15.3 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase SET PF00856.28 KXT04700.1 - 7.5e-10 39.4 0.0 2.4e-09 37.8 0.0 1.9 1 1 0 1 1 1 1 SET domain RF-1 PF00472.20 KXT04700.1 - 0.13 12.2 0.6 0.27 11.2 0.6 1.5 1 0 0 1 1 1 0 RF-1 domain DUF2433 PF10360.9 KXT04701.1 - 6.3e-47 158.7 0.0 1.1e-46 158.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos PF00149.28 KXT04701.1 - 0.00033 21.2 0.0 0.00065 20.3 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KXT04701.1 - 0.017 15.3 0.0 0.043 14.0 0.0 1.7 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain EF_assoc_2 PF08356.12 KXT04703.1 - 2.6e-32 110.7 0.0 5.3e-32 109.7 0.0 1.6 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 KXT04703.1 - 2.8e-28 97.3 0.1 5e-28 96.5 0.1 1.4 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 KXT04703.1 - 2.4e-22 79.3 0.0 7.3e-14 51.7 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KXT04703.1 - 7.6e-13 48.7 0.0 4.3e-07 30.2 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KXT04703.1 - 1.6e-08 34.6 0.0 0.00027 21.0 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 KXT04703.1 - 3.4e-06 27.2 0.2 0.28 11.2 0.0 3.2 2 1 0 3 3 3 2 Dynamin family EF-hand_6 PF13405.6 KXT04703.1 - 3.7e-06 26.4 1.4 0.042 13.8 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KXT04703.1 - 1.4e-05 24.2 1.1 0.12 12.0 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KXT04703.1 - 2.3e-05 24.7 0.7 0.026 15.0 0.2 2.8 2 0 0 2 2 2 2 EF-hand domain pair AAA_16 PF13191.6 KXT04703.1 - 0.0072 16.7 0.1 2 8.8 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain EF-hand_5 PF13202.6 KXT04703.1 - 0.0087 15.5 2.7 0.61 9.7 0.4 2.7 2 0 0 2 2 2 1 EF hand EF-hand_10 PF14788.6 KXT04703.1 - 0.0098 15.7 0.3 0.083 12.8 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 KXT04703.1 - 0.049 13.5 3.2 4.2 7.3 0.0 2.8 3 0 0 3 3 2 0 EF-hand domain pair AAA_22 PF13401.6 KXT04703.1 - 0.075 13.3 0.0 8.8 6.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KXT04703.1 - 0.11 12.2 0.0 8.1 6.3 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Septin PF00735.18 KXT04703.1 - 0.12 11.7 0.0 2.9 7.1 0.0 2.2 2 0 0 2 2 2 0 Septin AIG1 PF04548.16 KXT04703.1 - 0.16 11.2 0.1 6.6 6.0 0.1 2.3 2 0 0 2 2 2 0 AIG1 family RNA_helicase PF00910.22 KXT04703.1 - 0.16 12.3 0.0 12 6.3 0.0 2.7 2 0 0 2 2 2 0 RNA helicase UBA PF00627.31 KXT04704.1 - 2e-07 30.8 0.0 4.2e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain LRR_6 PF13516.6 KXT04705.1 - 9.5e-11 40.9 5.1 0.0043 17.0 0.0 7.7 8 0 0 8 8 8 1 Leucine Rich repeat LRR_4 PF12799.7 KXT04705.1 - 1.6e-07 31.5 8.2 0.28 11.7 0.0 5.4 4 2 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXT04705.1 - 0.0007 19.8 0.4 17 6.5 0.0 5.3 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_8 PF13855.6 KXT04705.1 - 0.0014 18.3 9.3 1.3 8.8 0.0 4.8 3 2 1 4 4 4 2 Leucine rich repeat SDA1 PF05285.12 KXT04705.1 - 2.4 7.5 22.2 3.8 6.8 22.2 1.2 1 0 0 1 1 1 0 SDA1 NOA36 PF06524.12 KXT04705.1 - 9.3 5.5 13.1 13 5.0 13.1 1.2 1 0 0 1 1 1 0 NOA36 protein Alg6_Alg8 PF03155.15 KXT04706.1 - 1.6e-118 396.7 23.4 8e-74 249.3 11.1 2.3 2 1 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family NPC1_N PF16414.5 KXT04707.1 - 1.3e-82 277.1 7.7 2.2e-82 276.3 7.7 1.4 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 KXT04707.1 - 3.2e-77 260.4 8.2 4.4e-76 256.6 8.1 2.3 2 1 0 2 2 2 1 Patched family Sterol-sensing PF12349.8 KXT04707.1 - 2e-51 173.8 5.8 2e-51 173.8 5.8 2.8 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation Folate_rec PF03024.14 KXT04707.1 - 0.0011 18.8 1.5 0.0029 17.5 1.5 1.6 1 0 0 1 1 1 1 Folate receptor family Aminotran_5 PF00266.19 KXT04708.1 - 3.2e-24 85.6 0.0 1.2e-18 67.2 0.0 2.9 1 1 1 2 2 2 2 Aminotransferase class-V ATG13 PF10033.9 KXT04709.1 - 3e-69 233.4 0.0 5.7e-69 232.5 0.0 1.5 1 0 0 1 1 1 1 Autophagy-related protein 13 Pyr_redox_3 PF13738.6 KXT04709.1 - 3.2e-12 46.3 0.0 1.2e-11 44.5 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KXT04709.1 - 1.8e-11 43.2 0.0 1.6e-10 40.1 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KXT04709.1 - 2.1e-10 40.3 0.0 2.6e-09 36.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXT04709.1 - 3.5e-07 30.4 0.0 1.8e-06 28.1 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KXT04709.1 - 2.9e-06 26.7 0.0 4.2e-05 22.9 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KXT04709.1 - 0.00085 19.0 0.8 1.8 8.0 0.1 3.4 2 1 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KXT04709.1 - 0.0012 18.0 0.1 0.0035 16.5 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 KXT04709.1 - 0.0045 17.0 0.1 1.5 8.8 0.2 3.9 3 1 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KXT04709.1 - 0.11 11.8 0.1 8.5 5.5 0.0 2.4 2 0 0 2 2 2 0 FAD binding domain Glyco_hydro_31 PF01055.26 KXT04726.1 - 3.5e-161 537.3 5.3 4.5e-161 536.9 5.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KXT04726.1 - 2.1e-36 124.7 0.1 4.8e-36 123.5 0.1 1.6 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase CBM_20 PF00686.19 KXT04726.1 - 3.7e-17 62.0 0.1 1e-16 60.6 0.1 1.8 1 0 0 1 1 1 1 Starch binding domain Gal_mutarotas_2 PF13802.6 KXT04726.1 - 2.6e-08 34.1 2.1 1.1e-07 32.1 2.1 2.2 1 0 0 1 1 1 1 Galactose mutarotase-like AMP-binding PF00501.28 KXT04727.1 - 2.7e-74 250.3 0.0 4.1e-74 249.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme HA2 PF04408.23 KXT04727.1 - 4.2e-18 65.6 0.0 1.3e-17 64.0 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) AMP-binding_C PF13193.6 KXT04727.1 - 1.3e-16 61.3 0.2 5.6e-16 59.3 0.2 2.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain OB_NTP_bind PF07717.16 KXT04727.1 - 1.9e-14 53.8 0.0 6.6e-14 52.0 0.0 2.0 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KXT04727.1 - 3.7e-14 53.0 0.0 1.1e-13 51.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RWD PF05773.22 KXT04727.1 - 1e-08 35.4 0.0 2.2e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 RWD domain DEAD PF00270.29 KXT04727.1 - 3.7e-08 33.4 0.3 8.2e-08 32.2 0.3 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_29 PF13555.6 KXT04727.1 - 0.0076 16.0 0.0 0.028 14.2 0.0 2.0 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SSE PF00437.20 KXT04727.1 - 0.016 14.3 0.0 0.031 13.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 KXT04727.1 - 0.035 13.4 0.0 0.077 12.3 0.0 1.4 1 0 0 1 1 1 0 KaiC PhoH PF02562.16 KXT04727.1 - 0.068 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 KXT04727.1 - 0.074 12.8 0.2 0.82 9.4 0.1 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_22 PF13401.6 KXT04727.1 - 0.13 12.5 3.7 2.3 8.5 3.7 2.7 1 1 0 1 1 1 0 AAA domain PIGA PF08288.12 KXT04728.1 - 1.5e-40 137.7 1.2 1.5e-40 137.7 1.2 1.9 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 KXT04728.1 - 3.2e-24 85.8 0.9 5.6e-24 85.0 0.9 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 KXT04728.1 - 1.3e-22 80.2 0.0 2e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KXT04728.1 - 1.5e-20 74.0 0.1 2.5e-20 73.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KXT04728.1 - 1.9e-08 34.9 0.0 3.2e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KXT04728.1 - 0.00072 19.9 0.0 0.0015 18.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 KXT04728.1 - 0.033 14.2 0.1 0.059 13.4 0.1 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like Lactamase_B_4 PF13691.6 KXT04729.1 - 3e-23 81.3 0.1 5.5e-23 80.4 0.1 1.5 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 KXT04729.1 - 1e-13 51.3 0.3 8.5e-06 25.4 0.0 3.0 3 0 0 3 3 3 2 Beta-lactamase superfamily domain ATP-synt_B PF00430.18 KXT04730.1 - 1.8 8.7 10.5 3.2 7.9 10.5 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Ribosomal_S7 PF00177.21 KXT04731.1 - 1.1e-36 125.7 2.1 1.4e-36 125.4 2.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Ribosomal_S7 PF00177.21 KXT04732.1 - 1.1e-36 125.7 2.1 1.4e-36 125.4 2.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Methyltransf_23 PF13489.6 KXT04734.1 - 2e-18 66.8 0.0 2.5e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXT04734.1 - 5.4e-11 43.0 0.0 1.3e-10 41.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXT04734.1 - 2.7e-09 37.0 0.0 3.8e-08 33.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXT04734.1 - 8.1e-08 32.8 0.0 1.6e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXT04734.1 - 9.2e-07 29.5 0.0 4.8e-06 27.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXT04734.1 - 9.3e-06 25.1 0.0 0.019 14.3 0.0 3.0 3 0 0 3 3 3 2 ubiE/COQ5 methyltransferase family MTS PF05175.14 KXT04734.1 - 0.00026 20.6 0.0 0.032 13.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_2 PF00891.18 KXT04734.1 - 0.00026 20.3 0.0 0.00057 19.2 0.0 1.6 1 1 0 1 1 1 1 O-methyltransferase domain CMAS PF02353.20 KXT04734.1 - 0.00087 18.7 0.0 0.0027 17.0 0.0 1.7 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.9 KXT04734.1 - 0.001 18.9 0.0 0.0016 18.2 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_4 PF02390.17 KXT04734.1 - 0.0025 17.3 0.0 0.0074 15.8 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_PK PF05891.12 KXT04734.1 - 0.017 14.7 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Pro-MCH PF05824.12 KXT04735.1 - 0.14 12.1 0.0 0.39 10.7 0.0 1.7 1 0 0 1 1 1 0 Pro-melanin-concentrating hormone (Pro-MCH) AAT PF03417.16 KXT04736.1 - 3e-31 108.9 0.0 3.6e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase DUF3878 PF12994.7 KXT04738.1 - 0.61 9.5 4.6 0.79 9.1 4.6 1.0 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3878) XRN_M PF17846.1 KXT04738.1 - 6.7 5.6 9.4 9 5.1 9.4 1.1 1 0 0 1 1 1 0 Xrn1 helical domain TPK_catalytic PF04263.16 KXT04739.1 - 7.1e-31 106.8 0.0 1e-30 106.2 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 KXT04739.1 - 4e-16 58.5 0.3 6.9e-16 57.7 0.3 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain NmrA PF05368.13 KXT04740.1 - 1.5e-32 113.0 0.0 2e-32 112.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXT04740.1 - 9e-18 64.8 0.0 1.1e-17 64.5 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXT04740.1 - 5.4e-06 26.0 0.0 7.2e-05 22.4 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KXT04740.1 - 0.00064 19.7 0.1 0.0011 18.9 0.1 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 KXT04740.1 - 0.0007 18.8 0.0 0.35 10.0 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein Sacchrp_dh_NADP PF03435.18 KXT04740.1 - 0.0031 17.8 0.0 0.0055 17.0 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 KXT04740.1 - 0.0062 16.7 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GDP_Man_Dehyd PF16363.5 KXT04740.1 - 0.02 14.3 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 KXT04740.1 - 0.029 14.8 0.1 0.063 13.7 0.1 1.6 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KXT04740.1 - 0.051 12.6 0.0 0.079 12.0 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase_2 PF02350.19 KXT04740.1 - 0.068 12.0 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase TAF1D PF15333.6 KXT04743.1 - 0.0033 17.2 1.4 0.0039 17.0 1.4 1.2 1 0 0 1 1 1 1 TATA box-binding protein-associated factor 1D DHHC PF01529.20 KXT04745.1 - 7.4e-36 123.2 3.3 7.4e-36 123.2 3.3 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase RRM_1 PF00076.22 KXT04747.1 - 4.1e-05 23.3 0.0 9.4e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EP400_N PF15790.5 KXT04747.1 - 0.0018 17.2 0.2 0.0026 16.7 0.2 1.1 1 0 0 1 1 1 1 E1A-binding protein p400, N-terminal DNA_pol_B PF00136.21 KXT04749.1 - 4.4e-104 348.7 0.0 6.2e-104 348.3 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KXT04749.1 - 7.7e-24 84.5 0.1 1.1e-14 54.4 0.0 2.6 3 0 0 3 3 3 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KXT04749.1 - 1.1e-17 64.2 6.5 1.1e-17 64.2 6.5 2.1 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta RNA_pol_Rpc82 PF05645.13 KXT04750.1 - 4.8e-38 131.4 0.0 9.4e-35 120.6 0.0 2.6 2 1 0 2 2 2 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 KXT04750.1 - 1.4e-11 44.3 7.1 1.6e-06 28.1 2.0 4.3 4 0 0 4 4 4 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 KXT04750.1 - 4.3e-08 33.0 0.1 0.0069 16.2 0.0 3.0 2 1 1 3 3 3 2 TFIIE alpha subunit MarR PF01047.22 KXT04750.1 - 0.067 13.1 0.2 7.5 6.6 0.0 3.8 4 0 0 4 4 4 0 MarR family DUF2999 PF11212.8 KXT04750.1 - 0.12 12.6 0.0 0.85 9.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2999) SurA_N_3 PF13624.6 KXT04750.1 - 1 9.1 4.9 1.1 9.0 1.6 2.3 2 0 0 2 2 2 0 SurA N-terminal domain HTH_20 PF12840.7 KXT04750.1 - 8.6 6.5 7.1 18 5.5 0.8 4.0 4 0 0 4 4 4 0 Helix-turn-helix domain ADH_zinc_N PF00107.26 KXT04751.1 - 1e-12 48.2 0.0 1.3e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXT04751.1 - 0.00092 18.8 0.0 0.73 9.3 0.0 2.1 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KXT04751.1 - 0.016 16.3 0.0 0.03 15.4 0.0 1.4 1 1 0 1 1 1 0 Zinc-binding dehydrogenase dsDNA_bind PF01984.20 KXT04752.1 - 1e-35 122.3 7.2 1.4e-35 122.0 7.2 1.2 1 0 0 1 1 1 1 Double-stranded DNA-binding domain HEAT_EZ PF13513.6 KXT04753.1 - 3e-26 91.5 15.6 1.1e-11 44.9 0.0 9.9 8 3 3 11 11 10 5 HEAT-like repeat HEAT PF02985.22 KXT04753.1 - 2.6e-22 77.0 12.9 0.00075 19.6 0.1 10.3 10 0 0 10 10 10 6 HEAT repeat HEAT_2 PF13646.6 KXT04753.1 - 3.5e-21 75.4 1.2 3.4e-05 24.2 0.0 7.0 4 2 2 6 6 6 4 HEAT repeats Cnd1 PF12717.7 KXT04753.1 - 2.5e-13 50.4 0.2 2.5e-05 24.4 0.0 4.6 4 0 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KXT04753.1 - 1e-11 45.3 0.0 0.0012 19.4 0.0 6.8 6 1 2 8 8 8 2 Vacuolar 14 Fab1-binding region IBN_N PF03810.19 KXT04753.1 - 4.9e-09 36.0 1.1 7.3e-07 29.0 0.1 3.8 2 2 1 3 3 3 1 Importin-beta N-terminal domain CLASP_N PF12348.8 KXT04753.1 - 9e-07 28.7 0.3 0.84 9.1 0.0 6.0 5 2 1 6 6 6 1 CLASP N terminal Adaptin_N PF01602.20 KXT04753.1 - 0.00011 20.9 1.7 0.02 13.5 0.0 3.5 2 2 1 3 3 3 2 Adaptin N terminal region HEAT_PBS PF03130.16 KXT04753.1 - 0.0029 18.1 0.2 15 6.6 0.0 5.6 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat FANCI_S2 PF14676.6 KXT04753.1 - 0.019 15.3 0.1 0.084 13.2 0.0 2.1 2 0 0 2 2 2 0 FANCI solenoid 2 Arm PF00514.23 KXT04753.1 - 0.019 15.0 0.1 14 5.9 0.0 4.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat TAF6_C PF07571.13 KXT04753.1 - 0.025 14.9 0.0 2.9 8.3 0.0 3.7 4 0 0 4 4 4 0 TAF6 C-terminal HEAT repeat domain Myf5 PF12232.8 KXT04753.1 - 0.046 14.5 0.4 2.2 9.1 0.0 3.2 3 0 0 3 3 3 0 Myogenic determination factor 5 V-ATPase_H_N PF03224.14 KXT04753.1 - 0.35 10.1 3.7 3.9 6.7 0.1 3.1 3 1 1 4 4 4 0 V-ATPase subunit H Tti2 PF10521.9 KXT04753.1 - 0.38 10.2 2.1 45 3.4 0.0 4.4 5 0 0 5 5 5 0 Tti2 family Urb2 PF10441.9 KXT04753.1 - 2.5 8.0 6.4 1.4 8.8 0.0 3.4 4 1 1 5 5 5 0 Urb2/Npa2 family BTB PF00651.31 KXT04754.1 - 0.0005 20.3 0.0 0.0011 19.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Cys_Met_Meta_PP PF01053.20 KXT04755.1 - 1.8e-23 82.7 0.0 2.4e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KXT04755.1 - 0.0049 16.1 0.0 0.0069 15.6 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Inhibitor_G39P PF11417.8 KXT04755.1 - 0.069 13.7 0.3 6.5 7.4 0.0 2.8 2 0 0 2 2 2 0 Loader and inhibitor of phage G40P Abhydrolase_3 PF07859.13 KXT04756.1 - 1.9e-51 175.0 0.0 2.5e-51 174.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXT04756.1 - 5.5e-08 32.5 0.0 0.0017 17.8 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.28 KXT04756.1 - 9.8e-07 28.0 0.7 6e-06 25.4 0.7 1.9 1 1 0 1 1 1 1 Carboxylesterase family DLH PF01738.18 KXT04756.1 - 3.4e-05 23.5 0.3 0.00014 21.4 0.1 1.9 2 0 0 2 2 2 1 Dienelactone hydrolase family Say1_Mug180 PF10340.9 KXT04756.1 - 0.0028 16.6 0.1 0.0098 14.8 0.1 1.7 1 1 0 1 1 1 1 Steryl acetyl hydrolase AXE1 PF05448.12 KXT04756.1 - 0.073 11.7 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Esterase_phd PF10503.9 KXT04756.1 - 0.14 11.7 0.0 0.3 10.5 0.0 1.5 1 0 0 1 1 1 0 Esterase PHB depolymerase RDD PF06271.12 KXT04757.1 - 0.0078 16.4 0.3 0.0078 16.4 0.3 1.8 2 0 0 2 2 2 1 RDD family Sas10_Utp3 PF04000.15 KXT04758.1 - 6.6e-16 58.7 0.3 6.6e-16 58.7 0.3 2.1 2 1 0 2 2 2 1 Sas10/Utp3/C1D family SPRY PF00622.28 KXT04759.1 - 1.1e-19 70.7 0.1 2.6e-19 69.5 0.1 1.7 1 0 0 1 1 1 1 SPRY domain Pentapeptide_4 PF13599.6 KXT04759.1 - 5.9e-12 45.6 14.5 2.9e-08 33.8 2.1 2.8 2 1 0 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 KXT04759.1 - 0.0011 19.1 18.6 0.021 15.0 3.7 4.1 2 2 1 3 3 3 2 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 KXT04759.1 - 0.0027 17.3 5.9 0.37 10.5 0.8 2.6 2 0 0 2 2 2 2 Pentapeptide repeats (8 copies) DUF1387 PF07139.11 KXT04760.1 - 0.15 11.8 3.1 0.23 11.1 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Peptidase_M16 PF00675.20 KXT04761.1 - 1.3e-16 60.9 0.0 2.4e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KXT04761.1 - 2.7e-09 37.3 0.0 5.5e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Inj_translocase PF16928.5 KXT04761.1 - 0.059 12.8 0.4 0.097 12.1 0.4 1.2 1 0 0 1 1 1 0 DNA/protein translocase of phage P22 injectosome SET PF00856.28 KXT04762.1 - 1.6e-08 35.1 0.0 3.9e-08 33.9 0.0 1.7 1 1 0 1 1 1 1 SET domain Polysacc_deac_1 PF01522.21 KXT04763.1 - 1.7e-19 70.0 0.0 2.4e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 KXT04763.1 - 8.4e-08 32.1 0.3 2.5e-07 30.5 0.2 1.8 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.9 KXT04763.1 - 0.003 16.0 0.0 0.0038 15.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein conserved in bacteria (DUF2194) VID27_PH PF17747.1 KXT04763.1 - 0.029 14.7 0.1 0.056 13.7 0.1 1.4 1 0 0 1 1 1 0 VID27 PH-like domain Polysacc_deac_1 PF01522.21 KXT04764.1 - 1.7e-19 70.0 0.0 2.4e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 KXT04764.1 - 8.4e-08 32.1 0.3 2.5e-07 30.5 0.2 1.8 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.9 KXT04764.1 - 0.003 16.0 0.0 0.0038 15.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein conserved in bacteria (DUF2194) VID27_PH PF17747.1 KXT04764.1 - 0.029 14.7 0.1 0.056 13.7 0.1 1.4 1 0 0 1 1 1 0 VID27 PH-like domain Polysacc_deac_1 PF01522.21 KXT04766.1 - 2.3e-19 69.5 0.0 4e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 KXT04766.1 - 1.1e-07 31.7 0.3 3.7e-07 30.0 0.2 1.8 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.9 KXT04766.1 - 0.0044 15.4 0.0 0.0057 15.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein conserved in bacteria (DUF2194) VID27_PH PF17747.1 KXT04766.1 - 0.042 14.1 0.1 0.08 13.2 0.1 1.4 1 0 0 1 1 1 0 VID27 PH-like domain Polysacc_deac_1 PF01522.21 KXT04767.1 - 2.4e-19 69.5 0.0 4.5e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 KXT04767.1 - 1.3e-07 31.4 0.5 3.3e-07 30.2 0.3 1.7 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.9 KXT04767.1 - 0.0046 15.4 0.0 0.0062 15.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein conserved in bacteria (DUF2194) Polysacc_deac_1 PF01522.21 KXT04768.1 - 2.5e-19 69.4 0.0 4.7e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 KXT04768.1 - 1.5e-07 31.3 0.5 3.6e-07 30.1 0.3 1.7 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.9 KXT04768.1 - 0.0049 15.3 0.0 0.0067 14.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein conserved in bacteria (DUF2194) Mak10 PF04112.13 KXT04769.1 - 4.1e-53 179.3 0.0 7.8e-53 178.4 0.0 1.5 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Abhydrolase_1 PF00561.20 KXT04770.1 - 2e-14 53.9 0.2 3.9e-13 49.6 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXT04770.1 - 2.9e-06 26.7 0.0 4e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF1057 PF06342.12 KXT04770.1 - 0.0098 15.0 0.0 0.014 14.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_3 PF07859.13 KXT04770.1 - 0.026 14.4 0.0 0.044 13.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold UPF0524 PF15823.5 KXT04770.1 - 0.15 11.4 0.2 0.23 10.8 0.2 1.2 1 0 0 1 1 1 0 UPF0524 of C3orf70 AKAP7_RIRII_bdg PF10470.9 KXT04771.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein Cupin_2 PF07883.11 KXT04772.1 - 0.0018 17.9 0.1 0.069 12.9 0.1 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_2 PF07883.11 KXT04773.1 - 0.012 15.3 4.5 0.52 10.1 4.5 2.5 1 1 0 1 1 1 0 Cupin domain Proteasome PF00227.26 KXT04775.1 - 6.7e-53 179.0 0.0 8.5e-53 178.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KXT04775.1 - 1.9e-12 46.6 0.0 3.6e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature F-box-like PF12937.7 KXT04777.1 - 0.00037 20.3 0.3 0.0075 16.1 0.1 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXT04777.1 - 0.12 12.3 0.1 0.12 12.3 0.1 2.9 3 0 0 3 3 3 0 F-box domain 4HBT_2 PF13279.6 KXT04779.1 - 9e-07 29.4 0.0 1.8e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Thioesterase-like superfamily ERM PF00769.19 KXT04779.1 - 0.00012 22.0 12.1 0.00018 21.4 8.0 2.3 2 0 0 2 2 2 1 Ezrin/radixin/moesin family ADIP PF11559.8 KXT04779.1 - 0.24 11.4 16.5 0.22 11.6 0.2 2.6 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding GAS PF13851.6 KXT04779.1 - 0.34 10.2 19.5 0.46 9.8 0.4 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding PIEZO PF15917.5 KXT04779.1 - 1.8 8.0 9.6 4.3 6.8 9.6 1.6 1 0 0 1 1 1 0 Piezo Myosin_tail_1 PF01576.19 KXT04779.1 - 1.8 6.2 24.1 14 3.3 24.8 1.8 1 1 1 2 2 2 0 Myosin tail Cnn_1N PF07989.11 KXT04779.1 - 3.2 8.0 14.0 1.8 8.8 0.6 3.1 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 DUF3450 PF11932.8 KXT04779.1 - 7.6 5.8 19.9 1 8.6 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) SnoaL_4 PF13577.6 KXT04781.1 - 7.6e-25 87.5 0.0 1.1e-24 87.0 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain DivIC PF04977.15 KXT04781.1 - 0.11 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Septum formation initiator Trimer_CC PF08954.11 KXT04781.1 - 0.14 11.7 0.3 0.41 10.2 0.3 1.7 1 0 0 1 1 1 0 Trimerisation motif L51_S25_CI-B8 PF05047.16 KXT04782.1 - 5.9e-15 54.9 0.1 1.1e-14 54.1 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Lactonase PF10282.9 KXT04783.1 - 2.3e-83 280.3 0.0 2.9e-83 280.0 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Pyr_redox_2 PF07992.14 KXT04784.1 - 8.7e-41 140.1 0.0 1e-40 139.8 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXT04784.1 - 1.2e-08 35.4 0.0 3.6e-05 24.2 0.1 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXT04784.1 - 0.015 14.4 0.0 5.1 6.1 0.0 2.4 2 1 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 KXT04784.1 - 0.018 14.1 0.2 3.9 6.4 0.0 3.1 2 1 0 3 3 3 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 KXT04784.1 - 0.038 14.4 0.1 1.2 9.7 0.0 2.9 3 0 0 3 3 3 0 Putative NAD(P)-binding NAD_binding_9 PF13454.6 KXT04784.1 - 0.066 13.2 0.0 0.6 10.1 0.0 2.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KXT04784.1 - 0.32 10.2 1.4 6.8 5.8 0.1 2.8 3 1 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_2_N PF02837.18 KXT04785.1 - 2.2e-17 63.5 0.1 5.3e-17 62.2 0.1 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 KXT04785.1 - 2.6e-11 44.2 0.0 6.4e-10 39.7 0.0 2.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.17 KXT04785.1 - 4.2e-09 35.9 0.0 8.5e-09 34.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain AAA_assoc_C PF09821.9 KXT04785.1 - 0.23 12.0 0.0 0.4 11.2 0.0 1.3 1 0 0 1 1 1 0 C-terminal AAA-associated domain MAPEG PF01124.18 KXT04786.1 - 4.6e-15 55.7 0.3 6.2e-15 55.2 0.3 1.1 1 0 0 1 1 1 1 MAPEG family Phage_attach PF05354.11 KXT04786.1 - 0.079 12.8 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 Phage Head-Tail Attachment PUL PF08324.11 KXT04788.1 - 3.1e-52 177.5 0.4 4.1e-52 177.1 0.4 1.1 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.14 KXT04788.1 - 1.3e-40 138.7 0.0 1.9e-40 138.2 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain MFS_1 PF07690.16 KXT04790.1 - 2.1e-32 112.4 30.9 2.1e-32 112.4 30.9 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily PTR2 PF00854.21 KXT04790.1 - 0.00063 18.7 1.7 0.00097 18.1 1.7 1.4 1 0 0 1 1 1 1 POT family MKT1_C PF12246.8 KXT04791.1 - 2.7e-61 206.9 0.0 4e-61 206.3 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 KXT04791.1 - 3.8e-28 97.7 0.0 1.1e-27 96.2 0.0 1.8 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 KXT04791.1 - 6.1e-06 26.7 0.0 0.0002 21.7 0.0 2.6 2 0 0 2 2 2 1 XPG N-terminal domain ATG13 PF10033.9 KXT04791.1 - 0.098 12.3 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 Autophagy-related protein 13 XPG_I PF00867.18 KXT04791.1 - 0.14 12.5 0.1 0.67 10.3 0.1 2.3 2 1 0 2 2 2 0 XPG I-region DEAD PF00270.29 KXT04792.1 - 3.8e-32 111.5 0.2 4.5e-15 55.9 0.0 3.1 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.31 KXT04792.1 - 4e-11 43.2 0.0 9.6e-10 38.8 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXT04792.1 - 2.7e-05 24.2 0.0 0.00012 22.1 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KXT04792.1 - 0.02 15.2 0.2 4.5 7.6 0.1 3.4 4 0 0 4 4 4 0 AAA domain Avian_gp85 PF03708.14 KXT04792.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Avian retrovirus envelope protein, gp85 Glyco_hydro_92 PF07971.12 KXT04793.1 - 1.5e-134 449.4 3.1 1.9e-134 449.1 3.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KXT04793.1 - 1.5e-46 159.2 2.0 2.5e-46 158.5 2.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain GDA1_CD39 PF01150.17 KXT04795.1 - 7.1e-102 341.2 0.0 8.9e-102 340.9 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Cohesin_load PF10345.9 KXT04796.1 - 1.3e-113 380.5 0.1 1.6e-113 380.2 0.1 1.0 1 0 0 1 1 1 1 Cohesin loading factor ANAPC3 PF12895.7 KXT04796.1 - 2.2 8.6 4.2 15 5.9 0.0 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Fungal_trans PF04082.18 KXT04797.1 - 2.2e-07 30.2 0.7 6e-07 28.8 0.7 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Cullin PF00888.22 KXT04798.1 - 2.5e-179 597.8 0.2 3.1e-179 597.6 0.2 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KXT04798.1 - 2.6e-24 85.0 1.0 6.6e-24 83.7 1.0 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain Peripla_BP_4 PF13407.6 KXT04798.1 - 0.019 14.6 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein domain HTH_9 PF08221.11 KXT04798.1 - 0.14 12.2 0.1 6.6 6.9 0.0 2.6 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain Sugar_tr PF00083.24 KXT04799.1 - 1.7e-70 238.2 19.0 2e-70 237.9 19.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXT04799.1 - 3e-27 95.5 22.4 3e-27 95.5 22.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF554 PF04474.12 KXT04799.1 - 0.031 13.7 5.9 0.026 14.0 3.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF554) adh_short PF00106.25 KXT04801.1 - 1.1e-36 126.1 0.0 1.5e-36 125.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT04801.1 - 1.6e-28 99.9 0.0 2.1e-28 99.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT04801.1 - 5.9e-05 23.0 0.1 0.0013 18.7 0.0 2.3 2 1 0 2 2 2 1 KR domain Epimerase PF01370.21 KXT04801.1 - 0.009 15.5 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF2397 PF09660.10 KXT04802.1 - 0.16 10.9 0.1 0.23 10.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) TauD PF02668.16 KXT04803.1 - 1.3e-24 87.4 0.0 1.8e-24 87.0 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KXT04803.1 - 0.068 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 CsiD Ribosomal_L28e PF01778.17 KXT04804.1 - 4.7e-38 130.5 1.1 8.4e-38 129.7 1.1 1.4 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.14 KXT04804.1 - 8.7e-28 96.9 19.0 8.7e-28 96.9 19.0 2.5 1 1 1 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 KXT04804.1 - 2.2e-05 24.0 17.9 2.9e-05 23.6 17.9 1.1 1 0 0 1 1 1 1 BUD22 Nop14 PF04147.12 KXT04804.1 - 0.016 13.5 32.2 0.02 13.1 32.2 1.1 1 0 0 1 1 1 0 Nop14-like family PYC_OADA PF02436.18 KXT04804.1 - 0.17 11.6 0.9 0.29 10.9 0.6 1.6 1 1 0 1 1 1 0 Conserved carboxylase domain TFIIF_alpha PF05793.12 KXT04804.1 - 1.1 7.7 29.1 1.5 7.3 29.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) OPT PF03169.15 KXT04805.1 - 3.6e-90 303.4 42.0 4.2e-90 303.1 42.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3093 PF11292.8 KXT04805.1 - 1.1 9.5 9.5 1.8 8.8 2.5 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3093) MFS_1 PF07690.16 KXT04806.1 - 3.3e-23 82.2 23.4 3.3e-23 82.2 23.4 2.2 1 1 2 3 3 3 2 Major Facilitator Superfamily PTR2 PF00854.21 KXT04806.1 - 0.00013 20.9 3.6 0.0003 19.8 3.6 1.5 1 0 0 1 1 1 1 POT family DUF4191 PF13829.6 KXT04806.1 - 0.0015 17.9 0.4 0.0015 17.9 0.4 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4191) CMS1 PF14617.6 KXT04807.1 - 3.3e-78 262.5 5.0 4e-78 262.3 5.0 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 KXT04807.1 - 5.2e-05 23.1 0.0 5.7e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ORC3_N PF07034.11 KXT04807.1 - 0.11 11.6 0.1 0.16 11.0 0.1 1.3 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus DUF3808 PF10300.9 KXT04808.1 - 0.11 11.2 0.0 0.19 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) NPP1 PF05630.11 KXT04809.1 - 1.8e-61 207.7 0.0 2e-61 207.5 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Octopine_DH PF02317.17 KXT04809.1 - 0.17 12.0 0.0 0.25 11.4 0.0 1.2 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain SET PF00856.28 KXT04813.1 - 5.3e-15 56.2 0.3 5.3e-15 56.2 0.3 4.0 3 2 0 3 3 3 1 SET domain AWS PF17907.1 KXT04813.1 - 3.6e-09 36.5 3.9 3.6e-09 36.5 3.9 2.3 2 0 0 2 2 2 1 AWS domain ATP-synt_Eps PF04627.13 KXT04814.1 - 2.3e-23 81.9 0.9 3.4e-23 81.4 0.9 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain PMBR PF09373.10 KXT04814.1 - 0.11 12.7 0.1 0.17 12.1 0.1 1.3 1 0 0 1 1 1 0 Pseudomurein-binding repeat OPT PF03169.15 KXT04815.1 - 1.6e-78 264.9 31.0 2e-78 264.6 31.0 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein HSP70 PF00012.20 KXT04816.1 - 6.2e-56 189.8 18.5 2.8e-54 184.3 2.2 3.3 3 1 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 KXT04816.1 - 0.026 13.3 0.0 0.06 12.2 0.0 1.5 1 0 0 1 1 1 0 MreB/Mbl protein ISG65-75 PF11727.8 KXT04816.1 - 0.12 11.6 4.2 0.27 10.4 4.2 1.6 1 0 0 1 1 1 0 Invariant surface glycoprotein BcrAD_BadFG PF01869.20 KXT04816.1 - 0.13 11.7 0.4 1.5 8.2 0.1 2.7 3 0 0 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family Spectrin_like PF18373.1 KXT04816.1 - 0.37 10.9 1.4 0.65 10.1 0.4 1.9 2 0 0 2 2 2 0 Spectrin like domain Rx_N PF18052.1 KXT04816.1 - 0.72 10.2 5.6 0.69 10.2 1.0 3.1 3 0 0 3 3 3 0 Rx N-terminal domain Laminin_II PF06009.12 KXT04816.1 - 1.5 8.8 13.0 0.32 11.0 5.8 2.6 2 0 0 2 2 2 0 Laminin Domain II AAA PF00004.29 KXT04817.1 - 2.8e-11 44.0 0.0 6.4e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KXT04817.1 - 4.8e-05 23.4 0.4 0.00023 21.1 0.0 2.0 2 0 0 2 2 2 1 Rad17 P-loop domain RuvB_N PF05496.12 KXT04817.1 - 6.1e-05 22.8 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KXT04817.1 - 0.0001 22.6 0.0 0.0006 20.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KXT04817.1 - 0.0002 21.4 0.0 0.00044 20.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 KXT04817.1 - 0.00084 19.3 0.0 0.0017 18.3 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_33 PF13671.6 KXT04817.1 - 0.0018 18.4 0.0 0.0054 16.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KXT04817.1 - 0.0065 15.7 0.0 0.015 14.5 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KXT04817.1 - 0.013 15.9 0.0 0.054 13.9 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 KXT04817.1 - 0.019 15.0 0.0 0.034 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KXT04817.1 - 0.022 14.5 0.3 0.047 13.4 0.3 1.4 1 0 0 1 1 1 0 AAA domain UPF0180 PF03698.13 KXT04817.1 - 0.029 14.6 0.3 0.069 13.3 0.3 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) AAA_17 PF13207.6 KXT04817.1 - 0.11 13.0 0.1 0.33 11.4 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KXT04817.1 - 0.13 12.8 0.0 0.43 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KXT04817.1 - 0.17 11.9 0.0 0.39 10.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 KXT04817.1 - 0.25 10.9 2.2 0.67 9.5 0.1 2.7 3 1 1 4 4 4 0 AAA domain Mannitol_dh_C PF08125.13 KXT04818.1 - 2.1e-77 259.9 0.0 3.1e-77 259.4 0.0 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 KXT04818.1 - 2.9e-42 144.4 0.0 4.8e-42 143.7 0.0 1.4 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain ADH_zinc_N PF00107.26 KXT04819.1 - 1.3e-05 25.2 0.0 2.1e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXT04819.1 - 0.077 12.9 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KXT04819.1 - 0.12 13.5 0.0 0.2 12.7 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase AA_permease PF00324.21 KXT04824.1 - 4.4e-134 447.7 42.4 5.3e-134 447.4 42.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXT04824.1 - 2.2e-39 135.5 45.0 3e-39 135.1 45.0 1.0 1 0 0 1 1 1 1 Amino acid permease SCO1-SenC PF02630.14 KXT04825.1 - 1e-48 164.6 0.0 1.5e-48 164.1 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 KXT04825.1 - 1.2e-05 25.2 0.0 2.5e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 KXT04825.1 - 0.0018 18.5 0.0 0.0043 17.3 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 KXT04825.1 - 0.022 14.5 0.0 0.16 11.6 0.0 2.1 1 1 0 1 1 1 0 Redoxin Abhydrolase_1 PF00561.20 KXT04827.1 - 4.3e-10 39.7 0.0 2.6e-08 33.9 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXT04827.1 - 1.7e-06 27.5 0.0 6e-06 25.7 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 VirJ PF06057.11 KXT04827.1 - 0.009 15.9 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Cutinase PF01083.22 KXT04827.1 - 0.09 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Cutinase Cullin PF00888.22 KXT04828.1 - 8.9e-187 622.5 10.5 1.4e-186 621.8 10.5 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KXT04828.1 - 2.5e-27 94.7 3.9 8.2e-27 93.0 3.9 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain WAC_Acf1_DNA_bd PF10537.9 KXT04828.1 - 0.089 13.3 3.0 0.27 11.8 1.1 2.7 2 0 0 2 2 2 0 ATP-utilising chromatin assembly and remodelling N-terminal DUF1803 PF08820.10 KXT04828.1 - 7 6.8 8.2 5.2 7.2 0.1 4.1 3 1 0 4 4 4 0 Domain of unknown function (DUF1803) CHCH PF06747.13 KXT04829.1 - 5.3e-07 29.6 3.1 9.7e-07 28.8 3.1 1.5 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 KXT04829.1 - 6.1e-06 26.6 1.8 1.2e-05 25.6 1.8 1.5 1 0 0 1 1 1 1 GCK domain PAE PF03283.13 KXT04830.1 - 0.12 11.4 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Pectinacetylesterase Fungal_trans PF04082.18 KXT04831.1 - 6.4e-16 58.2 0.0 1.4e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain RAMP PF04901.13 KXT04831.1 - 0.12 12.4 1.1 17 5.5 0.0 2.9 3 0 0 3 3 3 0 Receptor activity modifying family Porin_6 PF16939.5 KXT04831.1 - 0.15 11.2 0.1 0.23 10.5 0.1 1.2 1 0 0 1 1 1 0 Putative porin GCP_N_terminal PF17681.1 KXT04832.1 - 5.4e-70 236.4 0.7 1.1e-69 235.4 0.1 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KXT04832.1 - 4e-60 203.9 2.6 4e-60 203.9 2.6 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GerD PF17898.1 KXT04832.1 - 0.028 14.4 0.0 0.13 12.2 0.0 2.1 2 0 0 2 2 2 0 Spore germination GerD central core domain DUF677 PF05055.12 KXT04833.1 - 0.0028 16.6 0.1 0.005 15.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF677) PEP-utilisers_N PF05524.13 KXT04833.1 - 0.0044 17.2 2.5 0.95 9.6 0.6 2.6 2 0 0 2 2 2 1 PEP-utilising enzyme, N-terminal HAP1_N PF04849.13 KXT04833.1 - 0.0048 16.2 0.4 0.0048 16.2 0.4 3.5 2 1 1 3 3 3 1 HAP1 N-terminal conserved region Sec2p PF06428.11 KXT04833.1 - 0.036 14.0 0.4 0.036 14.0 0.4 3.5 4 0 0 4 4 3 0 GDP/GTP exchange factor Sec2p baeRF_family2 PF18844.1 KXT04833.1 - 0.054 13.6 0.4 0.13 12.3 0.4 1.7 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 2 CC2-LZ PF16516.5 KXT04833.1 - 0.06 13.7 0.3 0.06 13.7 0.3 3.5 4 0 0 4 4 4 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator SLATT_4 PF18186.1 KXT04833.1 - 0.097 12.3 0.8 1.5 8.5 0.3 2.4 2 1 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 4 FlaC_arch PF05377.11 KXT04833.1 - 0.22 12.0 2.8 12 6.4 0.1 3.3 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF4407 PF14362.6 KXT04833.1 - 0.27 10.6 16.4 0.065 12.6 9.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) ADIP PF11559.8 KXT04833.1 - 0.31 11.1 17.3 0.79 9.8 8.8 2.6 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding FlxA PF14282.6 KXT04833.1 - 0.44 10.6 10.3 0.071 13.1 0.9 3.3 3 1 0 3 3 3 0 FlxA-like protein XLF PF09302.11 KXT04833.1 - 0.85 9.8 5.8 1.6 8.9 0.4 2.9 3 0 0 3 3 3 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component LMBR1 PF04791.16 KXT04833.1 - 2 7.3 3.9 2.7 6.8 3.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4472 PF14739.6 KXT04833.1 - 2.4 8.9 8.8 23 5.8 4.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4472) Astro_capsid_p PF12226.8 KXT04833.1 - 2.6 7.1 6.3 5.3 6.1 6.3 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Taxilin PF09728.9 KXT04833.1 - 3.6 6.7 12.7 0.22 10.7 5.6 2.4 2 1 1 3 3 3 0 Myosin-like coiled-coil protein Golgin_A5 PF09787.9 KXT04833.1 - 3.6 7.0 20.5 0.086 12.3 6.8 2.8 3 1 0 3 3 3 0 Golgin subfamily A member 5 GARP PF16731.5 KXT04833.1 - 5.1 6.7 9.9 0.087 12.5 1.9 2.1 3 0 0 3 3 3 0 Glutamic acid/alanine-rich protein of Trypanosoma Fez1 PF06818.15 KXT04833.1 - 8.6 6.8 15.6 16 5.9 11.9 2.6 2 1 0 2 2 2 0 Fez1 BLOC1_2 PF10046.9 KXT04833.1 - 8.7 6.7 8.2 1.2 9.5 0.2 2.7 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Aa_trans PF01490.18 KXT04845.1 - 3.1e-18 65.7 20.9 4.2e-18 65.2 20.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.18 KXT04846.1 - 9.1e-25 87.2 31.5 1.2e-24 86.8 31.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Ribonucleas_3_3 PF14622.6 KXT04847.1 - 1.1e-25 90.2 0.0 1.8e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KXT04847.1 - 2e-09 38.0 0.0 4.4e-08 33.7 0.0 2.2 2 0 0 2 2 2 1 Ribonuclease III domain EXS PF03124.14 KXT04848.1 - 1.3e-92 310.7 26.9 1.6e-92 310.4 26.9 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.19 KXT04848.1 - 7e-68 230.3 10.3 7e-68 230.3 10.3 2.2 2 0 0 2 2 2 1 SPX domain FUR PF01475.19 KXT04848.1 - 0.039 14.1 0.2 0.087 13.0 0.2 1.5 1 0 0 1 1 1 0 Ferric uptake regulator family DUF3899 PF13038.6 KXT04848.1 - 0.046 14.2 4.5 0.71 10.4 1.2 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) GIDA_assoc PF13932.6 KXT04848.1 - 3.4 7.8 8.8 1.1 9.4 3.5 2.3 1 1 1 2 2 2 0 GidA associated domain EXS PF03124.14 KXT04849.1 - 1.3e-92 310.7 26.9 1.6e-92 310.4 26.9 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.19 KXT04849.1 - 4.4e-63 214.5 11.8 4.4e-63 214.5 11.8 2.2 2 0 0 2 2 2 1 SPX domain FUR PF01475.19 KXT04849.1 - 0.039 14.1 0.2 0.087 13.0 0.2 1.5 1 0 0 1 1 1 0 Ferric uptake regulator family DUF3899 PF13038.6 KXT04849.1 - 0.061 13.8 6.6 0.71 10.4 1.2 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) GIDA_assoc PF13932.6 KXT04849.1 - 3.5 7.8 8.8 1.1 9.4 3.4 2.3 1 1 1 2 2 2 0 GidA associated domain SNF2_N PF00176.23 KXT04850.1 - 4e-46 157.3 0.1 1.1e-45 155.9 0.1 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXT04850.1 - 1.3e-20 73.7 0.0 6e-20 71.6 0.0 2.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXT04850.1 - 3e-08 33.8 0.0 9.6e-08 32.2 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KXT04850.1 - 2.5e-07 30.2 0.0 5.7e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SWI2_SNF2 PF18766.1 KXT04850.1 - 8.1e-05 22.4 0.1 0.074 12.7 0.0 2.7 2 0 0 2 2 2 2 SWI2/SNF2 ATPase NAD_kinase PF01513.21 KXT04851.1 - 3e-43 148.1 0.0 6.1e-43 147.1 0.0 1.5 1 1 0 1 1 1 1 ATP-NAD kinase WD40 PF00400.32 KXT04852.1 - 3.6e-18 65.6 10.3 0.00014 22.6 0.1 7.3 6 1 1 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXT04852.1 - 5e-16 58.8 0.0 0.0081 16.4 0.0 5.4 3 2 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXT04852.1 - 2.4e-05 23.5 0.1 9.3e-05 21.5 0.0 1.9 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 KXT04852.1 - 0.0024 17.5 0.3 0.25 10.9 0.1 2.9 2 1 0 2 2 2 1 PQQ-like domain PQQ PF01011.21 KXT04852.1 - 0.014 15.3 0.0 0.24 11.4 0.0 3.0 4 0 0 4 4 4 0 PQQ enzyme repeat BamHI PF02923.15 KXT04852.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease BamHI CLTH PF10607.9 KXT04852.1 - 0.17 11.7 0.1 0.3 11.0 0.1 1.3 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain Bacteriocin_IIc PF10439.9 KXT04853.1 - 0.062 13.4 0.9 0.062 13.4 0.9 1.9 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Abhydrolase_3 PF07859.13 KXT04854.1 - 1.4e-31 110.1 0.0 1.9e-31 109.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold ARL6IP6 PF15062.6 KXT04855.1 - 0.027 14.6 0.0 0.063 13.4 0.0 1.6 1 0 0 1 1 1 0 Haemopoietic lineage transmembrane helix Sugar_tr PF00083.24 KXT04856.1 - 2e-91 307.1 23.4 2.5e-91 306.8 23.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXT04856.1 - 7.2e-12 44.9 48.8 5.5e-10 38.7 12.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXT04857.1 - 2e-91 307.1 23.4 2.5e-91 306.8 23.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXT04857.1 - 7.2e-12 44.9 48.8 5.5e-10 38.7 12.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 KXT04858.1 - 3.3e-11 42.6 0.0 3.4e-10 39.3 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 Ham1p_like PF01725.16 KXT04861.1 - 8.9e-56 188.8 0.0 1.3e-55 188.3 0.0 1.2 1 0 0 1 1 1 1 Ham1 family Ribosomal_S3Ae PF01015.18 KXT04862.1 - 6.9e-89 296.8 2.8 8.5e-89 296.5 2.8 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 KXT04862.1 - 0.067 13.7 0.1 0.72 10.4 0.0 2.2 2 0 0 2 2 2 0 Translation initiation factor SUI1 Ribosomal_S3Ae PF01015.18 KXT04863.1 - 6.9e-89 296.8 2.8 8.5e-89 296.5 2.8 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 KXT04863.1 - 0.067 13.7 0.1 0.72 10.4 0.0 2.2 2 0 0 2 2 2 0 Translation initiation factor SUI1 Ribosomal_S3Ae PF01015.18 KXT04864.1 - 6.9e-89 296.8 2.8 8.5e-89 296.5 2.8 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 KXT04864.1 - 0.067 13.7 0.1 0.72 10.4 0.0 2.2 2 0 0 2 2 2 0 Translation initiation factor SUI1 Ham1p_like PF01725.16 KXT04865.1 - 7.1e-55 185.8 0.0 1.2e-53 181.9 0.0 2.1 1 1 0 1 1 1 1 Ham1 family Abhydrolase_1 PF00561.20 KXT04866.1 - 2.5e-19 69.9 0.0 2.1e-12 47.3 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXT04866.1 - 3.7e-14 53.9 0.0 5.1e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KXT04866.1 - 3.3e-07 30.3 0.2 3.6e-05 23.6 0.1 2.1 1 1 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 KXT04866.1 - 1.3e-06 27.9 0.0 2.4e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF676 PF05057.14 KXT04866.1 - 0.00037 20.1 0.0 0.00058 19.4 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Thioesterase PF00975.20 KXT04866.1 - 0.0025 18.0 0.0 0.0034 17.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain LCAT PF02450.15 KXT04866.1 - 0.0048 16.1 0.0 0.0065 15.7 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Chlorophyllase PF07224.11 KXT04866.1 - 0.011 14.8 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Chlorophyllase2 PF12740.7 KXT04866.1 - 0.056 12.3 0.0 0.093 11.6 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Ser_hydrolase PF06821.13 KXT04866.1 - 0.082 12.8 0.0 0.14 12.0 0.0 1.4 1 1 0 1 1 1 0 Serine hydrolase PIG-X PF08320.12 KXT04867.1 - 1.2e-68 231.2 0.0 1.7e-68 230.7 0.0 1.2 1 0 0 1 1 1 1 PIG-X / PBN1 His_Phos_2 PF00328.22 KXT04867.1 - 3.5e-09 36.5 0.7 8.6e-08 31.9 0.1 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) TPP_enzyme_N PF02776.18 KXT04869.1 - 1.3e-33 116.0 0.6 6.1e-32 110.6 0.5 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KXT04869.1 - 5.8e-16 58.6 0.0 1.4e-15 57.4 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KXT04869.1 - 1.9e-07 30.9 0.0 5.1e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain MCM PF00493.23 KXT04870.1 - 1.9e-104 347.7 0.0 3.5e-104 346.8 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KXT04870.1 - 6e-36 123.1 0.2 1.5e-35 121.8 0.2 1.7 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KXT04870.1 - 7.8e-29 99.9 1.5 2.2e-28 98.5 1.5 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KXT04870.1 - 8.1e-15 55.3 0.2 2.1e-14 53.9 0.2 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KXT04870.1 - 6.9e-06 25.6 0.0 0.00095 18.6 0.0 2.5 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KXT04870.1 - 1.8e-05 24.7 0.0 4.4e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KXT04870.1 - 0.00038 20.3 0.0 0.0014 18.5 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KXT04870.1 - 0.046 13.4 0.0 1.4 8.6 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.29 KXT04870.1 - 0.11 12.9 0.1 0.58 10.6 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF4079 PF13301.6 KXT04871.1 - 0.8 9.9 6.4 6.7 6.9 7.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) FtsX PF02687.21 KXT04871.1 - 7.4 7.1 11.8 0.14 12.7 3.0 2.5 3 0 0 3 3 3 0 FtsX-like permease family Pkinase PF00069.25 KXT04872.1 - 1.8e-21 76.7 0.0 8.6e-21 74.5 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT04872.1 - 2.2e-08 33.7 0.0 6.8e-07 28.8 0.0 2.6 1 1 0 1 1 1 1 Protein tyrosine kinase CSTF1_dimer PF16699.5 KXT04873.1 - 0.034 13.9 1.3 0.2 11.4 0.1 2.8 2 1 1 3 3 3 0 Cleavage stimulation factor subunit 1, dimerisation domain Rho_Binding PF08912.11 KXT04873.1 - 0.76 10.6 4.3 1.5 9.7 0.8 2.3 2 0 0 2 2 2 0 Rho Binding DUF1996 PF09362.10 KXT04874.1 - 2.2e-74 250.4 0.4 3.1e-74 249.9 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) PH PF00169.29 KXT04875.1 - 0.0039 17.7 0.0 0.047 14.2 0.0 2.7 2 1 0 2 2 2 1 PH domain SQHop_cyclase_C PF13243.6 KXT04876.1 - 6.2e-42 143.8 0.1 2.2e-39 135.4 0.1 3.5 2 2 1 3 3 3 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 KXT04876.1 - 4.5e-39 134.3 2.2 2.6e-33 115.4 0.2 3.3 2 1 1 3 3 3 2 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 KXT04876.1 - 1.7e-22 78.8 10.7 4.2e-09 36.0 0.4 5.2 4 1 0 4 4 4 3 Prenyltransferase and squalene oxidase repeat RRM_1 PF00076.22 KXT04876.1 - 4.9e-06 26.3 0.0 1.3e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.24 KXT04876.1 - 0.00014 22.5 0.0 0.00026 21.6 0.0 1.4 1 0 0 1 1 1 1 Exonuclease TED_complement PF07678.14 KXT04876.1 - 0.0012 17.9 0.0 0.17 10.9 0.0 3.0 2 1 0 3 3 3 1 A-macroglobulin TED domain Pex14_N PF04695.13 KXT04876.1 - 0.44 11.2 14.5 1.2 9.8 14.5 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA PF03153.13 KXT04876.1 - 2.1 8.3 7.4 3.1 7.7 7.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Strabismus PF06638.11 KXT04877.1 - 0.41 9.2 2.1 0.59 8.7 2.1 1.2 1 0 0 1 1 1 0 Strabismus protein adh_short PF00106.25 KXT04878.1 - 3e-13 49.7 0.0 7.2e-13 48.4 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT04878.1 - 8.7e-06 25.5 0.0 1.6e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT04878.1 - 1.1e-05 25.4 0.0 2e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KXT04878.1 - 0.012 15.9 0.1 0.026 14.8 0.0 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KXT04878.1 - 0.073 13.1 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glyco_hydro_31 PF01055.26 KXT04879.1 - 1.5e-116 390.2 0.3 2e-116 389.8 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KXT04879.1 - 1.1e-15 57.7 0.1 3.1e-15 56.2 0.1 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like adh_short PF00106.25 KXT04880.1 - 2.4e-13 50.0 0.0 5.9e-13 48.7 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT04880.1 - 7.1e-06 25.7 0.0 1.4e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT04880.1 - 1e-05 25.5 0.0 1.7e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KXT04880.1 - 0.0098 16.2 0.1 0.022 15.0 0.0 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KXT04880.1 - 0.063 13.3 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 KXT04881.1 - 2.9e-27 95.4 0.2 4e-27 95.0 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT04881.1 - 2.1e-21 76.6 0.1 2.7e-21 76.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT04881.1 - 2.8e-05 24.1 0.4 4e-05 23.6 0.4 1.3 1 0 0 1 1 1 1 KR domain CoA_trans PF01144.23 KXT04881.1 - 0.0019 17.7 0.0 0.003 17.0 0.0 1.3 1 0 0 1 1 1 1 Coenzyme A transferase MFS_2 PF13347.6 KXT04882.1 - 3.4e-11 42.4 1.8 4.6e-11 41.9 1.8 1.2 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.16 KXT04882.1 - 1.7e-08 33.8 2.8 2e-08 33.6 2.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KXT04882.1 - 0.00021 20.3 3.6 0.0046 15.9 0.2 1.8 1 1 1 2 2 2 2 MFS_1 like family PUCC PF03209.15 KXT04882.1 - 0.0022 17.1 0.4 0.0032 16.5 0.4 1.2 1 0 0 1 1 1 1 PUCC protein Sugar_tr PF00083.24 KXT04882.1 - 0.01 14.8 1.7 0.01 14.7 1.7 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter DUF3082 PF11282.8 KXT04882.1 - 0.063 13.5 0.1 0.13 12.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3082) DUF1056 PF06341.11 KXT04882.1 - 0.87 9.9 4.9 1.1 9.6 0.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1056) MFS_2 PF13347.6 KXT04883.1 - 8.8e-10 37.7 5.7 8.8e-10 37.7 5.7 2.8 3 0 0 3 3 3 1 MFS/sugar transport protein PUCC PF03209.15 KXT04883.1 - 0.00012 21.2 3.9 0.00012 21.2 3.9 1.9 2 0 0 2 2 2 1 PUCC protein MFS_1_like PF12832.7 KXT04883.1 - 0.0026 16.7 1.4 0.012 14.5 1.4 2.2 1 1 0 1 1 1 1 MFS_1 like family PLDc_2 PF13091.6 KXT04884.1 - 4.8e-16 58.9 0.0 1.9e-08 34.3 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KXT04884.1 - 2.8e-07 30.5 4.2 0.0029 17.7 0.5 3.4 3 1 0 3 3 3 2 Phospholipase D Active site motif DUF3828 PF12883.7 KXT04884.1 - 0.095 13.1 0.0 18 5.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3828) PLDc_2 PF13091.6 KXT04885.1 - 1.8e-11 44.0 0.0 9.3e-05 22.3 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KXT04885.1 - 2.6e-07 30.5 4.2 0.0028 17.8 0.5 3.4 3 1 0 3 3 3 2 Phospholipase D Active site motif PAN_4 PF14295.6 KXT04889.1 - 6e-22 77.3 8.6 3e-07 30.3 0.2 3.7 3 0 0 3 3 3 3 PAN domain PAN_1 PF00024.26 KXT04889.1 - 2.9e-09 36.7 2.3 0.057 13.4 0.0 3.5 3 0 0 3 3 3 3 PAN domain EHN PF06441.12 KXT04890.1 - 1.7e-32 112.0 0.5 3e-32 111.2 0.5 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KXT04890.1 - 6.2e-07 29.3 0.0 9.9e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold PAN_4 PF14295.6 KXT04891.1 - 6e-22 77.3 8.6 3e-07 30.3 0.2 3.7 3 0 0 3 3 3 3 PAN domain PAN_1 PF00024.26 KXT04891.1 - 2.9e-09 36.7 2.3 0.057 13.4 0.0 3.5 3 0 0 3 3 3 3 PAN domain PAN_4 PF14295.6 KXT04892.1 - 6e-22 77.3 8.6 3e-07 30.3 0.2 3.7 3 0 0 3 3 3 3 PAN domain PAN_1 PF00024.26 KXT04892.1 - 2.9e-09 36.7 2.3 0.057 13.4 0.0 3.5 3 0 0 3 3 3 3 PAN domain Peptidase_M3 PF01432.20 KXT04893.1 - 4.2e-110 369.1 0.6 7.1e-110 368.4 0.6 1.4 1 0 0 1 1 1 1 Peptidase family M3 PNRC PF15365.6 KXT04894.1 - 5.6e-09 35.6 2.5 5.6e-09 35.6 2.5 3.0 2 0 0 2 2 2 1 Proline-rich nuclear receptor coactivator motif Peroxidase_2 PF01328.17 KXT04896.1 - 3.5e-46 158.1 0.0 4.7e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Opi1 PF08618.10 KXT04897.1 - 8.1e-27 94.5 14.7 3.1e-21 76.1 2.3 3.3 2 1 1 4 4 4 2 Transcription factor Opi1 Dioxygenase_C PF00775.21 KXT04898.1 - 3.9e-41 140.5 0.0 5.4e-41 140.0 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KXT04898.1 - 5.6e-23 80.6 0.1 2.3e-22 78.6 0.0 1.9 2 0 0 2 2 2 1 Catechol dioxygenase N terminus SpaA PF17802.1 KXT04898.1 - 0.00019 21.7 0.0 0.00037 20.7 0.0 1.5 1 0 0 1 1 1 1 Prealbumin-like fold domain CarboxypepD_reg PF13620.6 KXT04898.1 - 0.0011 19.2 0.0 0.012 15.9 0.0 2.6 1 1 1 2 2 2 1 Carboxypeptidase regulatory-like domain Dioxygenase_C PF00775.21 KXT04899.1 - 3.9e-41 140.5 0.0 5.4e-41 140.0 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KXT04899.1 - 5.6e-23 80.6 0.1 2.3e-22 78.6 0.0 1.9 2 0 0 2 2 2 1 Catechol dioxygenase N terminus SpaA PF17802.1 KXT04899.1 - 0.00019 21.7 0.0 0.00037 20.7 0.0 1.5 1 0 0 1 1 1 1 Prealbumin-like fold domain CarboxypepD_reg PF13620.6 KXT04899.1 - 0.0011 19.2 0.0 0.012 15.9 0.0 2.6 1 1 1 2 2 2 1 Carboxypeptidase regulatory-like domain Vps54 PF07928.12 KXT04900.1 - 2.2e-50 170.6 0.1 5.3e-50 169.3 0.1 1.7 1 0 0 1 1 1 1 Vps54-like protein Vps54_N PF10475.9 KXT04900.1 - 4.7e-10 39.2 0.1 1.3e-07 31.2 0.0 2.7 3 0 0 3 3 3 2 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 KXT04900.1 - 8.2e-08 32.3 0.0 1.6e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) UME PF08064.13 KXT04900.1 - 0.069 13.1 0.2 0.67 9.9 0.0 2.6 2 0 0 2 2 2 0 UME (NUC010) domain COG2 PF06148.11 KXT04900.1 - 0.079 13.0 1.5 0.36 10.9 1.5 2.2 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 FliJ PF02050.16 KXT04900.1 - 3.4 7.9 12.4 0.2 11.9 0.7 2.9 3 0 0 3 3 3 0 Flagellar FliJ protein Pkinase PF00069.25 KXT04901.1 - 1.7e-63 214.5 0.0 2.1e-63 214.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT04901.1 - 7.8e-22 77.8 0.0 3.3e-21 75.7 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXT04901.1 - 1.9e-06 27.4 0.0 8.9e-06 25.2 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KXT04901.1 - 0.0073 16.3 0.0 0.015 15.2 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family TPR_19 PF14559.6 KXT04902.1 - 2.6e-10 40.7 16.9 0.054 14.0 0.1 8.1 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 KXT04902.1 - 6.7e-08 32.7 20.6 0.58 11.1 0.1 9.6 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXT04902.1 - 4.4e-07 29.5 13.0 0.22 11.7 0.0 8.1 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_1 PF00515.28 KXT04902.1 - 1.5e-05 24.6 2.9 3.5 7.6 0.0 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 KXT04902.1 - 0.00013 21.9 8.5 5.5 7.5 0.0 6.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 KXT04902.1 - 0.00023 21.3 7.5 9 6.9 0.1 5.9 5 1 1 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KXT04902.1 - 0.06 13.6 13.4 5.1 7.4 0.3 6.0 5 2 1 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 KXT04902.1 - 0.26 11.0 3.6 3.8 7.3 0.2 3.2 3 0 0 3 3 3 0 TPR repeat SMI1_KNR4 PF09346.10 KXT04903.1 - 8.2e-33 113.6 0.0 2.1e-32 112.3 0.0 1.7 1 1 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) PhyH PF05721.13 KXT04904.1 - 1.4e-07 32.0 0.1 7.8e-06 26.3 0.1 2.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Ank_4 PF13637.6 KXT04905.1 - 2.3e-17 63.1 0.4 7.1e-08 32.8 0.0 2.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXT04905.1 - 3.3e-16 59.7 0.0 7.7e-14 52.1 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KXT04905.1 - 1.3e-13 50.7 0.0 7e-08 32.6 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KXT04905.1 - 1e-11 44.8 0.2 1.3e-08 34.9 0.1 3.2 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXT04905.1 - 1.2e-10 40.6 0.0 2.8e-06 27.2 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat NDUFA12 PF05071.16 KXT04906.1 - 5.2e-20 72.1 0.0 1e-19 71.2 0.0 1.5 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 NDUFA12 PF05071.16 KXT04907.1 - 7e-20 71.7 0.5 1.1e-19 71.0 0.5 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Rootletin PF15035.6 KXT04908.1 - 0.0082 16.2 0.9 0.013 15.5 0.9 1.2 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion DUF3461 PF11944.8 KXT04908.1 - 0.009 16.1 0.1 0.012 15.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3461) DUF1640 PF07798.11 KXT04908.1 - 0.062 13.3 0.4 0.08 13.0 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) DUF4446 PF14584.6 KXT04908.1 - 0.16 12.0 0.4 0.21 11.6 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Med21 PF11221.8 KXT04908.1 - 0.45 10.8 4.7 0.86 9.8 4.7 1.7 1 1 0 1 1 1 0 Subunit 21 of Mediator complex DMPK_coil PF08826.10 KXT04908.1 - 0.57 10.3 5.8 0.13 12.4 2.5 1.6 2 0 0 2 2 2 0 DMPK coiled coil domain like DUF5082 PF16888.5 KXT04910.1 - 0.015 15.6 7.8 0.015 15.6 7.8 2.6 3 1 0 3 3 3 0 Domain of unknown function (DUF5082) TfuA PF07812.12 KXT04910.1 - 0.022 14.5 2.5 0.023 14.4 0.7 1.9 1 1 2 3 3 3 0 TfuA-like protein Fib_alpha PF08702.10 KXT04910.1 - 0.6 10.3 14.8 2.5 8.3 1.5 2.7 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family MukF_M PF17192.4 KXT04910.1 - 0.73 9.6 12.1 0.086 12.6 5.5 2.0 1 1 1 2 2 2 0 MukF middle domain DIT1_PvcA PF05141.12 KXT04910.1 - 0.99 8.8 10.0 0.33 10.4 1.1 2.2 1 1 0 2 2 2 0 Pyoverdine/dityrosine biosynthesis protein SlyX PF04102.12 KXT04910.1 - 1.9 9.2 22.2 1.2 9.8 4.6 4.9 3 2 2 5 5 5 0 SlyX PKcGMP_CC PF16808.5 KXT04910.1 - 4.3 7.3 26.9 0.99 9.3 0.3 7.1 7 0 0 7 7 7 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Fanconi_C PF02106.15 KXT04911.1 - 0.0045 15.8 1.6 0.0059 15.4 1.6 1.2 1 0 0 1 1 1 1 Fanconi anaemia group C protein NOB1_Zn_bind PF08772.11 KXT04912.1 - 1.9e-31 108.0 2.9 3.2e-31 107.3 2.9 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 KXT04912.1 - 1.9e-31 108.4 0.4 5.8e-31 106.8 0.4 1.9 1 0 0 1 1 1 1 PIN domain of ribonuclease WRNPLPNID PF15017.6 KXT04912.1 - 0.0086 16.9 3.6 0.0086 16.9 3.6 2.7 3 1 1 4 4 4 1 Putative WW-binding domain and destruction box Zn-ribbon_8 PF09723.10 KXT04912.1 - 0.0093 16.1 2.0 0.03 14.5 0.8 2.2 2 0 0 2 2 2 1 Zinc ribbon domain zf-NADH-PPase PF09297.11 KXT04912.1 - 0.026 14.2 3.4 0.047 13.4 0.9 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain HypA PF01155.19 KXT04912.1 - 0.16 12.0 0.2 0.43 10.6 0.2 1.7 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Glycos_transf_1 PF00534.20 KXT04913.1 - 2.4e-33 115.1 0.0 3.6e-33 114.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KXT04913.1 - 1.4e-27 96.8 0.0 2.4e-27 96.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KXT04913.1 - 2.8e-10 40.5 0.0 1.9e-06 28.0 0.0 3.1 3 0 0 3 3 3 2 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 KXT04913.1 - 8.7e-10 38.9 0.0 3.2e-09 37.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KXT04913.1 - 1.5e-08 35.3 0.6 7.1e-07 29.8 0.1 2.7 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain HCMV_UL124 PF17609.2 KXT04913.1 - 0.0088 16.2 0.0 0.026 14.7 0.1 1.8 2 0 0 2 2 2 1 Family of unknown function TPR_2 PF07719.17 KXT04914.1 - 1.3e-31 106.1 21.9 0.0004 20.3 0.3 11.2 11 0 0 11 11 11 7 Tetratricopeptide repeat ANAPC3 PF12895.7 KXT04914.1 - 4.8e-30 103.6 22.5 1.7e-22 79.4 0.9 5.3 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 KXT04914.1 - 1.2e-25 88.2 17.7 3.5e-05 23.4 0.7 10.1 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_19 PF14559.6 KXT04914.1 - 2e-22 79.5 22.3 6.1e-06 26.7 0.1 7.8 6 2 2 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 KXT04914.1 - 1.9e-21 74.4 12.0 0.001 19.1 0.2 10.2 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_12 PF13424.6 KXT04914.1 - 6.5e-19 68.0 31.2 1.3e-09 38.2 1.6 9.3 6 3 2 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 KXT04914.1 - 2.3e-14 53.7 22.8 0.0016 19.1 0.6 7.3 6 2 1 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 KXT04914.1 - 7.1e-13 48.2 25.2 0.15 13.0 0.4 10.5 6 3 5 11 11 10 1 Tetratricopeptide repeat TPR_11 PF13414.6 KXT04914.1 - 1.1e-09 37.8 16.2 0.34 10.6 0.0 8.5 7 3 3 10 10 10 4 TPR repeat TPR_9 PF13371.6 KXT04914.1 - 2e-06 27.8 17.4 0.00098 19.2 0.5 6.6 5 2 1 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 KXT04914.1 - 2.1e-06 27.3 19.7 0.36 11.0 0.2 8.3 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_10 PF13374.6 KXT04914.1 - 2.2e-06 27.3 18.1 0.0056 16.5 0.2 8.6 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_6 PF13174.6 KXT04914.1 - 5.2e-06 26.8 22.2 0.29 11.9 0.1 8.2 8 2 1 9 9 6 3 Tetratricopeptide repeat TPR_4 PF07721.14 KXT04914.1 - 8.9e-06 25.9 6.5 1.3 9.9 0.0 5.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 KXT04914.1 - 0.00095 18.5 12.9 1 8.5 0.3 5.4 2 2 4 6 6 6 2 Tetratricopeptide repeat PPR PF01535.20 KXT04914.1 - 0.0015 18.7 0.5 6.7 7.2 0.0 4.1 4 0 0 4 4 3 0 PPR repeat SNAP PF14938.6 KXT04914.1 - 0.0016 17.9 17.6 0.094 12.1 0.4 4.9 4 1 0 5 5 5 2 Soluble NSF attachment protein, SNAP ChAPs PF09295.10 KXT04914.1 - 0.0026 16.8 0.8 0.3 10.0 0.0 2.7 2 1 0 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) SRP_TPR_like PF17004.5 KXT04914.1 - 0.0034 17.4 2.3 3.9 7.5 0.0 3.7 3 1 0 3 3 3 1 Putative TPR-like repeat HrpB1_HrpK PF09613.10 KXT04914.1 - 0.011 15.3 0.1 2.1 8.0 0.1 3.5 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) DUF627 PF04781.12 KXT04914.1 - 0.014 15.4 0.7 6.3 6.9 0.1 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF627) TPR_20 PF14561.6 KXT04914.1 - 0.02 15.2 10.6 3.1 8.2 0.0 5.4 5 1 0 5 5 5 0 Tetratricopeptide repeat Phasin_2 PF09361.10 KXT04914.1 - 0.11 12.8 2.0 10 6.4 0.1 2.9 2 0 0 2 2 2 0 Phasin protein ANAPC8 PF04049.13 KXT04914.1 - 0.13 12.3 0.6 0.59 10.2 0.0 2.2 2 0 0 2 2 2 0 Anaphase promoting complex subunit 8 / Cdc23 TPR_21 PF09976.9 KXT04914.1 - 0.17 11.6 11.4 0.93 9.2 1.1 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat-like domain Fis1_TPR_C PF14853.6 KXT04914.1 - 1.2 9.2 12.8 36 4.5 0.2 6.2 6 1 1 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.6 KXT04914.1 - 6.6 7.4 15.2 93 3.8 0.2 7.3 9 0 0 9 9 6 0 Tetratricopeptide repeat IBN_N PF03810.19 KXT04915.1 - 0.0029 17.5 0.1 0.01 15.8 0.1 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain Importin_rep PF18773.1 KXT04915.1 - 0.016 14.9 0.0 0.038 13.7 0.0 1.6 1 0 0 1 1 1 0 Importin 13 repeat Importin_rep_3 PF18806.1 KXT04915.1 - 0.019 15.0 0.0 0.6 10.2 0.0 3.4 3 0 0 3 3 3 0 Importin 13 repeat adh_short PF00106.25 KXT04917.1 - 1.5e-35 122.5 0.2 2e-35 122.0 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT04917.1 - 4.5e-21 75.5 0.1 1.8e-20 73.5 0.1 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT04917.1 - 9.5e-12 45.2 0.1 1.7e-11 44.3 0.1 1.4 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXT04917.1 - 5.1e-06 25.8 0.1 8.4e-06 25.1 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KXT04917.1 - 0.00048 19.7 0.1 0.099 12.1 0.1 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXT04917.1 - 0.0025 17.3 0.1 0.05 13.0 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 KXT04917.1 - 0.049 13.5 0.6 0.076 12.9 0.6 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KXT04917.1 - 0.056 12.4 0.0 0.075 12.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family AdoHcyase_NAD PF00670.21 KXT04917.1 - 0.11 12.5 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain F-box-like PF12937.7 KXT04918.1 - 0.0067 16.3 0.4 0.16 11.9 0.1 2.5 2 0 0 2 2 2 1 F-box-like EF-G-binding_N PF07299.11 KXT04918.1 - 0.011 16.2 0.1 0.024 15.2 0.1 1.5 1 0 0 1 1 1 0 Elongation factor G-binding protein, N-terminal F-box-like_2 PF13013.6 KXT04918.1 - 0.04 13.9 0.0 0.082 12.9 0.0 1.6 1 0 0 1 1 1 0 F-box-like domain Pkinase PF00069.25 KXT04919.1 - 5.7e-19 68.5 0.0 3.4e-18 66.0 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain AAA_18 PF13238.6 KXT04920.1 - 5.4e-27 94.9 0.1 5.4e-27 94.9 0.1 1.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KXT04920.1 - 2e-08 34.8 0.4 1.4e-07 32.0 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.6 KXT04920.1 - 8.4e-06 26.1 0.0 1.9e-05 25.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KXT04920.1 - 1.9e-05 24.9 0.0 0.00028 21.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain ADK PF00406.22 KXT04920.1 - 8.4e-05 22.7 0.8 0.0014 18.7 0.0 2.2 1 1 1 2 2 2 1 Adenylate kinase AAA PF00004.29 KXT04920.1 - 9.5e-05 22.8 0.0 0.00046 20.6 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) dNK PF01712.19 KXT04920.1 - 0.00029 20.8 2.7 0.032 14.1 0.0 2.1 1 1 1 2 2 2 2 Deoxynucleoside kinase Thymidylate_kin PF02223.17 KXT04920.1 - 0.0014 18.4 0.2 1.2 8.8 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase AAA_22 PF13401.6 KXT04920.1 - 0.0014 18.9 0.0 0.0028 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 KXT04920.1 - 0.0021 18.0 0.7 0.0032 17.4 0.1 1.6 2 0 0 2 2 1 1 NTPase Hydin_ADK PF17213.3 KXT04920.1 - 0.003 17.8 0.3 0.0066 16.8 0.0 1.6 2 0 0 2 2 2 1 Hydin Adenylate kinase-like domain AAA_16 PF13191.6 KXT04920.1 - 0.0049 17.3 0.0 0.012 16.0 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.18 KXT04920.1 - 0.0072 16.1 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 KXT04920.1 - 0.0095 15.9 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain KTI12 PF08433.10 KXT04920.1 - 0.012 15.1 0.0 0.03 13.8 0.0 1.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_24 PF13479.6 KXT04920.1 - 0.018 14.8 0.1 0.055 13.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KXT04920.1 - 0.025 14.6 0.1 0.061 13.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KXT04920.1 - 0.029 14.5 0.1 0.052 13.6 0.1 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 KXT04920.1 - 0.054 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 KXT04920.1 - 0.064 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MeaB PF03308.16 KXT04920.1 - 0.088 11.8 1.2 0.36 9.8 0.0 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP_bind_1 PF03029.17 KXT04920.1 - 0.09 12.5 0.3 0.17 11.7 0.0 1.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_19 PF13245.6 KXT04920.1 - 0.14 12.5 0.1 0.26 11.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 KXT04920.1 - 0.14 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain CR6_interact PF10147.9 KXT04920.1 - 0.24 11.1 4.5 0.34 10.6 4.5 1.2 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Pyr_excise PF03013.14 KXT04920.1 - 0.4 10.7 2.1 1.4 8.9 0.6 2.1 1 1 1 2 2 2 0 Pyrimidine dimer DNA glycosylase AMPK1_CBM PF16561.5 KXT04921.1 - 2.6e-25 88.4 0.0 5.6e-25 87.4 0.0 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 KXT04921.1 - 1.7e-23 82.7 0.8 1.7e-23 82.7 0.8 3.6 3 0 0 3 3 3 1 5'-AMP-activated protein kinase beta subunit, interaction domain CBM53 PF16760.5 KXT04921.1 - 0.011 16.3 0.0 0.026 15.1 0.0 1.6 1 0 0 1 1 1 0 Starch/carbohydrate-binding module (family 53) DER1 PF04511.15 KXT04922.1 - 2.6e-33 115.6 5.5 3e-33 115.4 5.5 1.0 1 0 0 1 1 1 1 Der1-like family MFS_1 PF07690.16 KXT04923.1 - 5.4e-31 107.8 30.4 5.4e-31 107.8 30.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DNA_binding_1 PF01035.20 KXT04924.1 - 5.5e-24 84.1 0.2 2.1e-23 82.2 0.0 2.1 2 0 0 2 2 2 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Urocanase PF01175.18 KXT04924.1 - 0.012 15.3 0.1 0.021 14.5 0.1 1.4 1 0 0 1 1 1 0 Urocanase Rossmann-like domain Glyco_hydro_43 PF04616.14 KXT04925.1 - 8.8e-29 100.7 0.0 1.3e-28 100.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Sybindin PF04099.12 KXT04926.1 - 2.3e-24 85.9 0.0 2.9e-24 85.6 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family DUF3920 PF13058.6 KXT04926.1 - 0.13 12.5 0.0 0.19 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3920) ABC_membrane PF00664.23 KXT04927.1 - 2.5e-56 191.4 26.9 3.2e-35 122.1 6.5 3.3 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXT04927.1 - 2.1e-54 183.7 0.1 5.5e-32 111.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KXT04927.1 - 5e-07 29.4 3.1 0.14 11.5 0.0 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KXT04927.1 - 1.1e-06 28.8 0.3 0.0052 16.6 0.1 3.7 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KXT04927.1 - 2.5e-06 28.2 0.0 0.0025 18.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KXT04927.1 - 4.8e-05 23.4 0.1 0.065 13.3 0.0 2.9 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KXT04927.1 - 9.8e-05 22.6 0.2 2.4 8.4 0.1 3.5 3 0 0 3 3 3 2 AAA domain DUF87 PF01935.17 KXT04927.1 - 9.8e-05 22.5 0.3 0.053 13.6 0.0 2.8 2 0 0 2 2 2 1 Helicase HerA, central domain RsgA_GTPase PF03193.16 KXT04927.1 - 0.00012 22.0 0.2 0.17 11.8 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KXT04927.1 - 0.00016 22.1 0.6 1.3 9.3 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 KXT04927.1 - 0.00044 19.9 1.1 0.62 9.8 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.23 KXT04927.1 - 0.0025 17.9 2.6 0.27 11.3 0.0 3.1 3 0 0 3 3 3 1 Dynamin family AAA_25 PF13481.6 KXT04927.1 - 0.0053 16.4 1.2 2 7.9 0.0 3.2 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 KXT04927.1 - 0.0056 16.4 0.1 3.6 7.3 0.0 3.0 3 0 0 3 3 3 1 IstB-like ATP binding protein T2SSE PF00437.20 KXT04927.1 - 0.0084 15.2 0.4 0.22 10.5 0.1 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA PF00004.29 KXT04927.1 - 0.011 16.2 0.2 5.8 7.3 0.0 3.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KXT04927.1 - 0.033 14.3 0.0 2.9 8.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KXT04927.1 - 0.035 13.6 0.1 11 5.5 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_15 PF13175.6 KXT04927.1 - 0.045 13.5 2.4 0.16 11.6 0.1 2.8 4 0 0 4 4 4 0 AAA ATPase domain AAA_30 PF13604.6 KXT04927.1 - 0.049 13.3 1.8 10 5.8 0.0 3.3 3 0 0 3 3 3 0 AAA domain CbiA PF01656.23 KXT04927.1 - 0.057 13.5 0.9 0.29 11.2 0.0 2.6 3 0 0 3 3 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_5 PF07728.14 KXT04927.1 - 0.063 13.3 0.4 15 5.5 0.1 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) TrwB_AAD_bind PF10412.9 KXT04927.1 - 0.082 11.8 1.0 1.9 7.3 0.0 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain RNA_helicase PF00910.22 KXT04927.1 - 0.11 12.9 0.2 32 5.0 0.0 3.1 3 0 0 3 3 3 0 RNA helicase AAA_24 PF13479.6 KXT04927.1 - 0.11 12.2 0.4 8.8 6.0 0.0 2.6 3 0 0 3 3 2 0 AAA domain Roc PF08477.13 KXT04927.1 - 0.11 12.7 0.5 23 5.2 0.1 2.9 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase DUF2075 PF09848.9 KXT04927.1 - 0.16 11.2 0.2 11 5.1 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 KXT04927.1 - 0.17 11.3 0.3 9.2 5.7 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_18 PF13238.6 KXT04927.1 - 0.21 12.2 0.3 44 4.6 0.1 2.8 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KXT04927.1 - 0.23 10.7 1.9 6.6 6.0 0.1 2.7 3 0 0 3 3 3 0 Zeta toxin FtsK_SpoIIIE PF01580.18 KXT04927.1 - 0.23 10.8 0.9 4 6.7 0.1 2.6 3 0 0 3 3 3 0 FtsK/SpoIIIE family NACHT PF05729.12 KXT04927.1 - 0.28 11.1 1.7 6.5 6.6 0.1 2.4 2 0 0 2 2 2 0 NACHT domain cobW PF02492.19 KXT04927.1 - 0.32 10.6 2.5 2.2 7.8 0.5 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain HAT_KAT11 PF08214.11 KXT04928.1 - 8.3e-80 268.7 0.0 1.1e-79 268.3 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein HOASN PF14515.6 KXT04928.1 - 0.084 13.3 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Haem-oxygenase-associated N-terminal helices Tudor_3 PF18115.1 KXT04929.1 - 1.1e-20 73.1 0.1 2.7e-20 72.0 0.1 1.7 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain Rad9_Rad53_bind PF08605.10 KXT04929.1 - 2.5e-09 37.4 0.0 4.7e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT PF00533.26 KXT04929.1 - 9.7e-06 25.9 0.0 7.8e-05 23.0 0.0 2.3 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KXT04929.1 - 0.0056 17.1 0.0 0.016 15.6 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 KXT04929.1 - 0.016 15.3 0.0 8.9 6.5 0.0 2.5 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Peptidase_C2 PF00648.21 KXT04930.1 - 2.2e-45 155.0 0.2 1.9e-44 151.9 0.2 2.1 1 1 0 1 1 1 1 Calpain family cysteine protease PTP_tm PF18861.1 KXT04931.1 - 0.057 13.4 0.1 0.1 12.6 0.1 1.3 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Acyltransferase PF01553.21 KXT04932.1 - 5.8e-29 100.4 0.4 1.6e-28 99.0 0.0 1.8 2 0 0 2 2 2 1 Acyltransferase Acyltransf_C PF16076.5 KXT04932.1 - 2.6e-13 49.9 0.3 7.1e-13 48.4 0.3 1.7 1 0 0 1 1 1 1 Acyltransferase C-terminus Pkinase PF00069.25 KXT04933.1 - 1.4e-55 188.5 0.3 2.8e-53 181.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXT04933.1 - 1.1e-36 126.5 0.1 1.3e-35 123.0 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KXT04933.1 - 1.8e-07 30.7 0.0 7.3e-07 28.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KXT04933.1 - 0.00035 19.5 0.0 0.00084 18.2 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KXT04933.1 - 0.02 14.8 2.9 0.021 14.7 0.3 2.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 KXT04934.1 - 1.1e-59 201.9 0.1 2.7e-53 181.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXT04934.1 - 1.9e-37 129.0 0.0 1.2e-35 123.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KXT04934.1 - 5.4e-08 32.5 0.0 7.1e-07 28.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KXT04934.1 - 0.00033 19.6 0.0 0.0008 18.3 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KXT04934.1 - 0.013 15.4 2.5 0.014 15.3 0.2 2.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family Cupin_4 PF08007.12 KXT04935.1 - 0.018 14.5 0.0 0.048 13.1 0.0 1.6 2 0 0 2 2 2 0 Cupin superfamily protein Cupin_2 PF07883.11 KXT04935.1 - 0.024 14.4 0.6 0.17 11.6 0.0 2.5 2 0 0 2 2 2 0 Cupin domain JmjC PF02373.22 KXT04935.1 - 0.055 13.9 0.1 0.17 12.3 0.1 1.8 1 0 0 1 1 1 0 JmjC domain, hydroxylase Cupin_1 PF00190.22 KXT04935.1 - 0.065 12.8 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Cupin Pkinase PF00069.25 KXT04936.1 - 1.9e-55 188.1 0.3 3.3e-53 180.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXT04936.1 - 1.3e-36 126.2 0.1 1.5e-35 122.7 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KXT04936.1 - 2.2e-07 30.5 0.0 8.3e-07 28.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KXT04936.1 - 0.00041 19.3 0.0 0.00094 18.1 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KXT04936.1 - 0.017 15.1 0.3 0.017 15.1 0.3 2.0 2 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 KXT04937.1 - 1.5e-59 201.5 0.1 3.2e-53 180.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXT04937.1 - 2.5e-37 128.6 0.0 1.5e-35 122.8 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KXT04937.1 - 6.8e-08 32.2 0.0 8.1e-07 28.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KXT04937.1 - 0.00038 19.3 0.0 0.0009 18.1 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KXT04937.1 - 0.016 15.2 0.2 0.016 15.2 0.2 2.0 2 1 0 2 2 2 0 Phosphotransferase enzyme family GSH_synth_ATP PF03917.17 KXT04939.1 - 9.4e-143 475.5 0.0 1.1e-142 475.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 KXT04939.1 - 5e-33 113.6 0.0 9e-33 112.8 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase ABC_membrane PF00664.23 KXT04940.1 - 2.2e-87 293.2 30.3 1.4e-47 162.7 11.1 2.7 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXT04940.1 - 2.5e-51 173.8 0.0 8.8e-30 104.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KXT04940.1 - 1e-09 38.2 3.8 0.0022 17.5 0.1 4.1 2 2 2 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KXT04940.1 - 6.4e-06 26.2 0.8 0.12 12.4 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXT04940.1 - 8.8e-05 22.5 0.2 0.021 14.8 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KXT04940.1 - 0.00052 20.4 0.3 1.4 9.2 0.1 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KXT04940.1 - 0.0006 19.5 0.5 0.29 10.9 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KXT04940.1 - 0.00092 19.1 0.4 0.39 10.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KXT04940.1 - 0.0011 19.5 0.5 0.096 13.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KXT04940.1 - 0.014 15.7 1.6 2.7 8.3 0.1 3.3 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 KXT04940.1 - 0.019 15.1 2.2 3.3 7.7 0.1 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain Dynamin_N PF00350.23 KXT04940.1 - 0.021 14.9 2.0 1.7 8.7 0.0 3.0 3 0 0 3 3 3 0 Dynamin family AAA_30 PF13604.6 KXT04940.1 - 0.046 13.4 0.2 2 8.1 0.0 2.7 2 1 0 2 2 2 0 AAA domain Roc PF08477.13 KXT04940.1 - 0.081 13.2 0.2 13 6.0 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_27 PF13514.6 KXT04940.1 - 0.17 11.4 0.8 0.52 9.9 0.0 2.1 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 KXT04940.1 - 0.18 11.5 0.8 3.3 7.4 0.0 2.8 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_15 PF13175.6 KXT04940.1 - 0.24 11.1 0.5 1.9 8.1 0.0 2.3 3 0 0 3 3 3 0 AAA ATPase domain ABC_membrane PF00664.23 KXT04941.1 - 1.5e-67 228.1 28.6 4.7e-41 141.3 5.4 3.7 4 0 0 4 4 4 3 ABC transporter transmembrane region ABC_tran PF00005.27 KXT04941.1 - 2.5e-51 173.8 0.0 8.9e-30 104.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KXT04941.1 - 9.1e-10 38.3 3.7 0.0022 17.5 0.1 4.1 2 2 2 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KXT04941.1 - 6.5e-06 26.2 0.8 0.12 12.4 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXT04941.1 - 8.7e-05 22.5 0.2 0.021 14.7 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KXT04941.1 - 0.00054 20.4 0.3 1.5 9.2 0.1 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KXT04941.1 - 0.00061 19.5 0.5 0.3 10.9 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KXT04941.1 - 0.00094 19.1 0.4 0.4 10.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KXT04941.1 - 0.0012 19.4 0.5 0.097 13.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KXT04941.1 - 0.013 15.8 1.5 2.7 8.3 0.1 3.2 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 KXT04941.1 - 0.019 15.1 2.2 3.3 7.7 0.1 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain Dynamin_N PF00350.23 KXT04941.1 - 0.021 14.9 2.0 1.7 8.7 0.0 3.0 3 0 0 3 3 3 0 Dynamin family AAA_30 PF13604.6 KXT04941.1 - 0.045 13.5 0.2 2 8.1 0.0 2.7 2 1 0 2 2 2 0 AAA domain Roc PF08477.13 KXT04941.1 - 0.083 13.1 0.2 13 6.0 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_27 PF13514.6 KXT04941.1 - 0.17 11.4 0.8 0.52 9.9 0.0 2.1 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 KXT04941.1 - 0.18 11.6 0.8 3.3 7.4 0.0 2.8 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_15 PF13175.6 KXT04941.1 - 0.24 11.0 0.5 2 8.1 0.0 2.3 3 0 0 3 3 3 0 AAA ATPase domain CAF-1_p150 PF11600.8 KXT04942.1 - 0.029 14.1 18.5 0.031 14.0 18.5 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Presenilin PF01080.17 KXT04942.1 - 3.4 6.3 4.1 3.1 6.5 4.1 1.0 1 0 0 1 1 1 0 Presenilin Peroxidase_2 PF01328.17 KXT04943.1 - 3.4e-09 37.5 0.3 3.6e-09 37.4 0.3 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 AMP-binding PF00501.28 KXT04945.1 - 7e-61 206.1 0.0 9.1e-61 205.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXT04945.1 - 1.5e-08 35.5 0.0 3.3e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Phage_T7_Capsid PF05396.11 KXT04945.1 - 0.054 13.9 0.0 0.098 13.0 0.0 1.3 1 0 0 1 1 1 0 Phage T7 capsid assembly protein Pkinase PF00069.25 KXT04946.1 - 7.4e-32 110.7 0.0 2.1e-31 109.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT04946.1 - 1.6e-23 83.3 0.0 3.1e-23 82.4 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXT04946.1 - 0.0056 15.5 0.0 0.0077 15.1 0.0 1.3 1 1 0 1 1 1 1 Fungal protein kinase F-box-like PF12937.7 KXT04947.1 - 0.0067 16.3 0.1 0.019 14.9 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXT04947.1 - 0.14 12.1 0.0 0.48 10.4 0.0 1.9 1 0 0 1 1 1 0 F-box domain Pkinase PF00069.25 KXT04948.1 - 2.4e-22 79.6 0.0 5.3e-13 48.9 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXT04948.1 - 1.1e-08 34.7 0.0 0.00058 19.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase DUF572 PF04502.13 KXT04949.1 - 8.2e-71 239.3 10.0 9.9e-71 239.1 10.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-ACC PF17848.1 KXT04949.1 - 0.01 15.9 2.7 0.097 12.8 0.5 2.6 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain zinc_ribbon_12 PF11331.8 KXT04949.1 - 0.15 11.9 0.2 18 5.3 0.0 2.4 2 0 0 2 2 2 0 Probable zinc-ribbon domain Presenilin PF01080.17 KXT04949.1 - 1.2 7.8 2.1 1.7 7.3 2.1 1.1 1 0 0 1 1 1 0 Presenilin SMAP PF15477.6 KXT04949.1 - 1.4 10.0 4.4 29 5.7 2.8 2.7 2 1 0 2 2 2 0 Small acidic protein family zf-C2HE PF16278.5 KXT04949.1 - 3.2 8.3 7.3 25 5.4 0.2 3.4 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger ELO PF01151.18 KXT04950.1 - 1.6e-60 204.7 20.5 2e-60 204.4 20.5 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF2235 PF09994.9 KXT04957.1 - 4.6e-46 157.5 0.0 6.7e-46 156.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) MMR_HSR1 PF01926.23 KXT04957.1 - 1.3e-08 34.9 0.0 3.4e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 KXT04957.1 - 1.7e-06 27.5 0.3 0.0059 15.9 0.0 2.2 2 0 0 2 2 2 2 Septin Ras PF00071.22 KXT04957.1 - 1.2e-05 24.9 0.6 5.9e-05 22.7 0.6 1.9 1 1 0 1 1 1 1 Ras family RsgA_GTPase PF03193.16 KXT04957.1 - 4.2e-05 23.5 0.4 9.8e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase Roc PF08477.13 KXT04957.1 - 6.3e-05 23.2 0.7 0.0011 19.2 0.7 2.4 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Palm_thioest PF02089.15 KXT04957.1 - 0.014 15.3 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 Palmitoyl protein thioesterase AAA_23 PF13476.6 KXT04957.1 - 0.019 15.5 0.0 0.038 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.12 KXT04957.1 - 0.033 13.6 0.0 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 KXT04957.1 - 0.11 12.8 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.18 KXT04957.1 - 0.11 12.0 0.0 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_29 PF13555.6 KXT04957.1 - 0.12 12.1 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynamin_N PF00350.23 KXT04957.1 - 0.17 12.0 0.0 0.39 10.7 0.0 1.7 1 0 0 1 1 1 0 Dynamin family AIG1 PF04548.16 KXT04957.1 - 0.19 11.0 0.1 0.53 9.6 0.0 1.8 2 0 0 2 2 2 0 AIG1 family PWWP PF00855.17 KXT04958.1 - 4.7e-17 62.2 0.0 4.7e-17 62.2 0.0 3.4 3 1 0 3 3 3 1 PWWP domain Pkinase PF00069.25 KXT04959.1 - 3.5e-68 229.8 0.0 4.7e-68 229.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT04959.1 - 6.6e-36 123.9 0.0 9.8e-36 123.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXT04959.1 - 6.5e-06 25.7 0.0 9.8e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KXT04959.1 - 0.0037 16.7 0.0 0.0079 15.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Adeno_52K PF03052.15 KXT04960.1 - 0.12 11.8 0.0 0.36 10.2 0.0 1.7 2 0 0 2 2 2 0 Adenoviral protein L1 52/55-kDa HVSL PF09749.9 KXT04961.1 - 6.6e-80 268.0 0.0 7.4e-80 267.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein BssS PF13991.6 KXT04961.1 - 0.078 13.1 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 BssS protein family Vps8 PF12816.7 KXT04962.1 - 2.2e-68 229.7 0.1 1.2e-67 227.3 0.0 2.3 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 KXT04962.1 - 5.4e-10 39.3 0.6 0.00013 21.8 0.0 3.3 3 0 0 3 3 3 2 Region in Clathrin and VPS GAT PF03127.14 KXT04962.1 - 0.0032 17.7 0.2 0.022 15.0 0.0 2.6 2 0 0 2 2 2 1 GAT domain KR PF08659.10 KXT04962.1 - 0.012 15.5 0.1 0.91 9.4 0.1 2.4 2 0 0 2 2 2 0 KR domain zf-C3H2C3 PF17122.5 KXT04962.1 - 0.013 15.6 0.2 0.013 15.6 0.2 1.9 2 0 0 2 2 2 0 Zinc-finger Zn_ribbon_17 PF17120.5 KXT04962.1 - 0.017 14.7 0.0 0.039 13.6 0.0 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 KXT04962.1 - 0.14 12.5 0.0 0.38 11.1 0.0 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KXT04962.1 - 0.18 11.7 0.5 0.52 10.2 0.0 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KXT04962.1 - 0.37 10.6 1.9 0.33 10.7 0.2 1.9 2 0 0 2 2 2 0 RING-like zinc finger zf-C2H2 PF00096.26 KXT04963.1 - 2e-07 31.1 4.9 0.00045 20.5 0.3 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KXT04963.1 - 0.018 15.5 2.6 0.024 15.0 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 KXT04963.1 - 0.052 14.4 0.1 0.052 14.4 0.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger ParBc_2 PF08857.11 KXT04963.1 - 0.27 11.3 4.0 1.9 8.5 1.1 2.6 1 1 1 2 2 2 0 Putative ParB-like nuclease Dak2 PF02734.17 KXT04963.1 - 0.56 10.1 7.1 6.2 6.7 0.7 3.4 2 1 1 3 3 3 0 DAK2 domain Coat_F PF07875.12 KXT04963.1 - 0.94 9.8 3.6 0.62 10.3 0.3 2.4 3 0 0 3 3 3 0 Coat F domain zinc_ribbon_9 PF14369.6 KXT04963.1 - 3.7 7.9 4.8 2.4 8.5 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon Glyco_hydro_2_C PF02836.17 KXT04964.1 - 2.2e-12 46.7 0.2 5.6e-11 42.1 0.2 2.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 KXT04964.1 - 1e-11 45.0 0.0 2e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 KXT04964.1 - 1e-06 29.4 0.0 2e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 HpcH_HpaI PF03328.14 KXT04965.1 - 2.1e-39 135.0 0.0 5.1e-39 133.7 0.0 1.6 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 KXT04965.1 - 1.2e-14 54.3 0.0 2.4e-07 30.3 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold Herpes_pp85 PF04637.12 KXT04966.1 - 0.089 11.2 0.3 0.1 11.0 0.3 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Fumerase_C PF05683.12 KXT04968.1 - 0.035 13.4 0.0 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 Fumarase C-terminus RRM_1 PF00076.22 KXT04969.1 - 7.6e-21 73.7 0.0 9.9e-21 73.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXT04969.1 - 0.0016 18.5 0.0 0.0026 17.8 0.0 1.3 1 1 0 1 1 1 1 RNA recognition motif PAP_PilO PF06864.12 KXT04969.1 - 0.19 10.5 0.0 0.23 10.2 0.0 1.1 1 0 0 1 1 1 0 Pilin accessory protein (PilO) RRM_occluded PF16842.5 KXT04969.1 - 0.19 11.6 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif DUF3752 PF12572.8 KXT04970.1 - 2.9e-44 151.2 11.9 2.9e-44 151.2 11.9 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3752) TIP41 PF04176.13 KXT04971.1 - 1e-65 220.4 0.3 1.2e-65 220.2 0.3 1.1 1 0 0 1 1 1 1 TIP41-like family Polo_box_3 PF18544.1 KXT04971.1 - 0.027 15.1 0.2 0.19 12.4 0.1 2.4 3 0 0 3 3 3 0 Polo box domain GST_N_3 PF13417.6 KXT04972.1 - 3.6e-11 43.3 0.0 6.8e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KXT04972.1 - 1.9e-05 24.9 0.0 4e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXT04972.1 - 6e-05 23.0 0.3 0.00013 21.9 0.3 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RabGAP-TBC PF00566.18 KXT04973.1 - 2.8e-35 121.9 0.0 2.5e-27 96.0 0.0 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain DDT PF02791.17 KXT04973.1 - 0.038 14.3 0.1 0.076 13.3 0.1 1.4 1 0 0 1 1 1 0 DDT domain RabGAP-TBC PF00566.18 KXT04974.1 - 2.8e-35 121.9 0.0 2.5e-27 96.0 0.0 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain DDT PF02791.17 KXT04974.1 - 0.038 14.3 0.1 0.076 13.3 0.1 1.4 1 0 0 1 1 1 0 DDT domain RRN3 PF05327.11 KXT04975.1 - 4.2e-155 517.5 0.0 4.2e-155 517.5 0.0 2.0 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 NOA36 PF06524.12 KXT04975.1 - 0.41 9.9 12.4 0.62 9.3 5.5 2.3 2 0 0 2 2 2 0 NOA36 protein FAM176 PF14851.6 KXT04975.1 - 0.48 10.1 9.5 4.4 7.0 0.5 2.3 2 0 0 2 2 2 0 FAM176 family Sigma70_ner PF04546.13 KXT04975.1 - 0.76 9.6 9.1 6.9 6.5 3.5 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region MAM33 PF02330.16 KXT04975.1 - 0.87 9.5 7.3 4.3 7.2 0.4 2.2 2 0 0 2 2 2 0 Mitochondrial glycoprotein BUD22 PF09073.10 KXT04975.1 - 0.91 8.8 7.5 2.5 7.4 2.4 2.1 2 0 0 2 2 2 0 BUD22 DUF3246 PF11596.8 KXT04975.1 - 2.3 7.6 6.6 8.2 5.8 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) Cwf_Cwc_15 PF04889.12 KXT04975.1 - 3.1 7.5 16.4 3.2 7.4 4.3 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein GCIP PF13324.6 KXT04975.1 - 3.6 7.1 9.4 4.3 6.9 0.1 2.5 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting UQ_con PF00179.26 KXT04978.1 - 7.8e-26 90.4 0.2 1.4e-25 89.5 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme NUDIX PF00293.28 KXT04978.1 - 8.4e-08 32.3 0.0 2.1e-07 31.1 0.0 1.7 2 0 0 2 2 2 1 NUDIX domain RWD PF05773.22 KXT04978.1 - 0.052 13.8 1.0 0.4 11.0 0.3 2.2 1 1 1 2 2 2 0 RWD domain Sec-ASP3 PF15432.6 KXT04978.1 - 0.099 12.8 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Accessory Sec secretory system ASP3 DUF1180 PF06679.12 KXT04979.1 - 1.5 9.2 5.2 1.7 9.0 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Epimerase PF01370.21 KXT04980.1 - 8.7e-10 38.5 0.0 2.6e-09 36.9 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXT04980.1 - 2e-09 37.6 0.0 2.9e-09 37.1 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding HIM1 PF08732.10 KXT04980.1 - 1.2e-06 28.2 0.0 1.5e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 HIM1 NmrA PF05368.13 KXT04980.1 - 7.5e-05 22.4 0.4 0.00042 20.0 0.3 2.0 1 1 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 KXT04980.1 - 0.0046 17.4 0.0 0.02 15.3 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.25 KXT04981.1 - 4.7e-42 143.7 0.1 7e-42 143.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT04981.1 - 1.3e-24 87.1 0.0 1.7e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT04981.1 - 1.7e-05 24.8 0.0 3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KXT04981.1 - 0.0019 17.7 0.0 0.0027 17.2 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KXT04981.1 - 0.0023 17.1 0.1 0.0032 16.7 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 KXT04981.1 - 0.056 13.5 0.2 0.14 12.2 0.2 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 KXT04981.1 - 0.13 12.2 0.1 0.22 11.4 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 KXT04982.1 - 7.9e-41 140.8 0.6 9.7e-41 140.5 0.6 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXT04982.1 - 7.2e-06 26.2 0.6 2.1e-05 24.7 0.6 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain TAP_C PF03943.13 KXT04983.1 - 5.5e-13 48.3 0.4 1.2e-12 47.3 0.4 1.6 1 0 0 1 1 1 1 TAP C-terminal domain LRR_9 PF14580.6 KXT04983.1 - 8.6e-06 25.4 0.9 1.5e-05 24.6 0.9 1.4 1 0 0 1 1 1 1 Leucine-rich repeat RRM_9 PF18444.1 KXT04983.1 - 0.0011 18.7 0.0 0.0034 17.2 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif NTF2 PF02136.20 KXT04983.1 - 0.053 14.1 0.0 0.22 12.1 0.0 2.0 1 1 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain LRR_1 PF00560.33 KXT04983.1 - 0.34 11.6 1.4 64 4.7 0.2 3.1 2 0 0 2 2 2 0 Leucine Rich Repeat LRR_8 PF13855.6 KXT04983.1 - 0.43 10.4 7.5 2.4 8.0 7.6 2.3 1 1 0 1 1 1 0 Leucine rich repeat LRR_4 PF12799.7 KXT04983.1 - 2.2 8.8 16.0 0.15 12.5 5.9 3.3 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) DHO_dh PF01180.21 KXT04985.1 - 1.8e-64 217.8 0.6 1.7e-51 175.2 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase Allexi_40kDa PF05549.11 KXT04985.1 - 0.27 10.7 1.4 1.6 8.2 1.1 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein FAM220 PF15487.6 KXT04985.1 - 0.73 9.4 5.0 1.6 8.3 5.0 1.5 1 0 0 1 1 1 0 FAM220 family DUF3713 PF12506.8 KXT04985.1 - 0.78 10.1 2.2 3.8 7.8 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3713) ApoLp-III PF07464.11 KXT04985.1 - 0.85 9.7 5.7 0.97 9.5 1.3 2.6 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Methyltransf_8 PF05148.15 KXT04986.1 - 4.6e-58 196.6 0.4 2.1e-55 188.0 0.0 3.3 2 1 1 3 3 3 2 Hypothetical methyltransferase Methyltransf_11 PF08241.12 KXT04986.1 - 1.1e-05 26.0 0.0 4.2e-05 24.1 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXT04986.1 - 0.00027 21.6 0.0 0.0069 17.1 0.0 2.9 1 1 0 1 1 1 1 Methyltransferase domain Pyocin_S PF06958.12 KXT04986.1 - 0.02 15.4 1.5 0.055 14.0 1.5 1.7 1 0 0 1 1 1 0 S-type Pyocin Methyltransf_32 PF13679.6 KXT04986.1 - 0.17 11.9 0.0 0.17 11.9 0.0 3.2 3 1 0 3 3 3 0 Methyltransferase domain PolyA_pol PF01743.20 KXT04986.1 - 10 6.6 7.2 5 7.6 4.0 2.2 2 1 0 2 2 2 0 Poly A polymerase head domain CPSase_L_D2 PF02786.17 KXT04987.1 - 1.8e-106 354.3 0.0 2.5e-83 278.8 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 KXT04987.1 - 3.8e-41 140.3 0.2 1.5e-40 138.3 0.1 2.2 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 KXT04987.1 - 8.5e-19 67.8 0.0 3.8e-09 36.4 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KXT04987.1 - 9.7e-18 64.4 0.2 1.7e-08 34.2 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 KXT04987.1 - 1.9e-09 37.4 0.0 0.001 18.8 0.0 3.0 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon GARS_A PF01071.19 KXT04987.1 - 3.7e-07 30.1 0.7 0.016 15.0 0.0 2.7 3 0 0 3 3 3 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.14 KXT04987.1 - 1.7e-05 24.9 0.1 0.11 12.5 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_5 PF13549.6 KXT04987.1 - 8.2e-05 22.2 0.0 0.1 12.1 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.11 KXT04987.1 - 0.00014 21.5 0.0 0.068 12.8 0.0 2.7 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.6 KXT04987.1 - 0.13 11.9 0.0 0.49 10.0 0.0 2.1 1 0 0 1 1 1 0 ATP-grasp domain zf_Rg PF17915.1 KXT04988.1 - 0.1 12.0 0.2 0.16 11.4 0.2 1.3 1 0 0 1 1 1 0 Reverse gyrase zinc finger Peptidase_M28 PF04389.17 KXT04989.1 - 1.4e-38 132.6 0.0 2.1e-38 132.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KXT04989.1 - 2.4e-11 43.5 0.1 5.5e-11 42.3 0.1 1.7 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KXT04989.1 - 0.0024 17.6 0.0 0.0054 16.4 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 KXT04989.1 - 0.044 12.8 0.0 0.24 10.4 0.0 1.9 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase DUF3433 PF11915.8 KXT04990.1 - 4.4e-30 104.0 15.7 4.5e-15 55.9 3.8 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) DUF4834 PF16118.5 KXT04990.1 - 0.062 14.3 0.5 0.3 12.1 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) 2-Hacid_dh_C PF02826.19 KXT04991.1 - 7.8e-42 142.6 0.0 3.7e-28 98.1 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXT04991.1 - 0.047 13.4 0.0 0.078 12.6 0.0 1.5 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain IlvN PF07991.12 KXT04991.1 - 0.095 12.3 0.1 0.29 10.7 0.0 1.8 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 KXT04991.1 - 0.17 12.4 0.0 0.64 10.6 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent FeS_assembly_P PF01883.19 KXT04992.1 - 9.1e-11 41.8 0.1 2e-10 40.7 0.1 1.6 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein DAD PF02109.16 KXT04993.1 - 3e-50 169.1 2.1 3.8e-50 168.8 2.1 1.1 1 0 0 1 1 1 1 DAD family Pex14_N PF04695.13 KXT04993.1 - 0.0052 17.5 0.8 0.0071 17.0 0.8 1.2 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Arb2 PF09757.9 KXT04993.1 - 0.039 13.1 0.0 0.053 12.6 0.0 1.1 1 0 0 1 1 1 0 Arb2 domain DUF2486 PF10667.9 KXT04993.1 - 0.045 14.0 1.4 0.06 13.6 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) ANAPC1 PF12859.7 KXT04993.1 - 0.73 10.4 4.6 0.36 11.4 2.7 1.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 1 Rax2 PF12768.7 KXT04994.1 - 4.5e-62 209.3 7.2 6e-61 205.6 0.1 4.9 5 1 1 6 6 6 2 Cortical protein marker for cell polarity DUF4690 PF15756.5 KXT04994.1 - 3.1 8.5 7.2 0.5 11.0 0.8 3.1 4 0 0 4 4 4 0 Small Novel Rich in Cartilage Acyl_transf_3 PF01757.22 KXT04995.1 - 1.7e-23 83.2 32.9 3.2e-23 82.4 32.9 1.4 1 1 0 1 1 1 1 Acyltransferase family Lon_C PF05362.13 KXT04996.1 - 9e-62 208.3 0.0 2.2e-61 207.0 0.0 1.7 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KXT04996.1 - 1.6e-34 119.7 0.0 4.4e-34 118.2 0.0 1.8 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KXT04996.1 - 8.4e-22 78.0 0.0 2.4e-21 76.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXT04996.1 - 5.9e-07 29.6 0.0 1.3e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KXT04996.1 - 2.8e-06 27.6 0.0 9.7e-06 25.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KXT04996.1 - 4.1e-05 23.9 0.2 0.00073 19.8 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_PrkA PF08298.11 KXT04996.1 - 0.00011 21.2 0.0 0.00023 20.2 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.12 KXT04996.1 - 0.00012 21.9 0.1 0.0007 19.4 0.0 2.2 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain ChlI PF13541.6 KXT04996.1 - 0.00019 21.3 0.0 0.00047 20.0 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 KXT04996.1 - 0.0025 18.2 3.3 0.0051 17.2 0.1 3.1 3 1 0 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.17 KXT04996.1 - 0.0046 16.7 0.2 0.035 13.8 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_14 PF13173.6 KXT04996.1 - 0.0093 16.0 0.0 0.026 14.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KXT04996.1 - 0.0095 16.5 0.3 0.12 12.9 0.0 2.9 3 0 0 3 3 3 1 AAA domain ClpB_D2-small PF10431.9 KXT04996.1 - 0.016 15.3 0.4 0.073 13.1 0.4 2.2 1 0 0 1 1 1 0 C-terminal, D2-small domain, of ClpB protein F-box-like_2 PF13013.6 KXT04996.1 - 0.022 14.8 0.0 0.056 13.4 0.0 1.6 1 0 0 1 1 1 0 F-box-like domain AAA_30 PF13604.6 KXT04996.1 - 0.038 13.7 0.0 0.085 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KXT04996.1 - 0.078 13.4 0.0 0.28 11.6 0.0 2.0 2 0 0 2 2 1 0 RNA helicase NTPase_1 PF03266.15 KXT04996.1 - 0.1 12.5 0.2 1 9.2 0.0 2.4 1 1 1 2 2 2 0 NTPase TetR_C_29 PF17938.1 KXT04996.1 - 0.14 12.3 0.1 1.2 9.3 0.0 2.4 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain RsgA_GTPase PF03193.16 KXT04996.1 - 0.14 12.1 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_7 PF12775.7 KXT04996.1 - 0.26 10.8 1.0 0.46 10.0 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region ABC_tran PF00005.27 KXT04996.1 - 5.5 7.5 5.9 0.83 10.2 0.1 2.5 3 1 0 3 3 2 0 ABC transporter SnoaL_2 PF12680.7 KXT04999.1 - 0.11 13.2 0.1 0.17 12.6 0.1 1.3 1 0 0 1 1 1 0 SnoaL-like domain Thymidylat_synt PF00303.19 KXT05002.1 - 1.3e-105 352.4 0.0 1.6e-105 352.1 0.0 1.1 1 0 0 1 1 1 1 Thymidylate synthase ACPS PF01648.20 KXT05003.1 - 5.4e-06 26.5 0.7 4.2e-05 23.7 0.2 2.4 2 1 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 KXT05003.1 - 0.014 15.5 0.3 1.3 9.2 0.0 2.5 2 0 0 2 2 2 0 4'-phosphopantetheinyl transferase N-terminal domain SpoIIID PF12116.8 KXT05004.1 - 0.064 13.4 0.3 0.094 12.8 0.3 1.2 1 0 0 1 1 1 0 Stage III sporulation protein D Speriolin_N PF15058.6 KXT05004.1 - 0.41 10.7 1.8 0.42 10.7 0.8 1.5 1 1 0 1 1 1 0 Speriolin N terminus Bromodomain PF00439.25 KXT05005.1 - 2.2e-34 117.4 1.1 4.5e-18 65.1 0.6 2.6 2 0 0 2 2 2 2 Bromodomain Tannase PF07519.11 KXT05006.1 - 0.1 11.5 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Tannase and feruloyl esterase HET PF06985.11 KXT05007.1 - 1.2e-33 116.6 1.8 2.3e-33 115.6 1.8 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Erg28 PF03694.13 KXT05008.1 - 1e-45 154.6 0.9 1.4e-45 154.2 0.9 1.2 1 0 0 1 1 1 1 Erg28 like protein Ctr PF04145.15 KXT05009.1 - 9.2e-30 104.2 1.7 1.2e-29 103.9 1.7 1.1 1 0 0 1 1 1 1 Ctr copper transporter family MFS_1 PF07690.16 KXT05010.1 - 1.1e-29 103.5 27.0 1.1e-29 103.5 27.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TetR_C_8 PF14278.6 KXT05010.1 - 0.11 12.6 0.0 0.33 11.1 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator C-terminal region PigN PF04987.14 KXT05012.1 - 1.2e-158 528.8 23.1 1.2e-158 528.8 23.1 1.5 2 0 0 2 2 2 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 KXT05012.1 - 1.1e-07 31.8 2.4 1.8e-06 27.8 2.3 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KXT05012.1 - 3.3e-07 30.0 0.1 5.2e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 KXT05012.1 - 0.00013 21.4 0.0 0.00022 20.7 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily PglZ PF08665.12 KXT05012.1 - 0.074 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 PglZ domain Sulfate_transp PF00916.20 KXT05013.1 - 9.7e-106 353.7 25.3 1.4e-105 353.2 25.3 1.3 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KXT05013.1 - 1.9e-09 37.1 0.0 4e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KXT05013.1 - 1.9 8.9 19.6 0.041 14.3 4.1 3.1 2 1 0 2 2 2 0 Molybdate transporter of MFS superfamily SNN_transmemb PF09049.10 KXT05013.1 - 7.7 6.6 8.8 0.32 11.0 1.7 2.5 2 0 0 2 2 2 0 Stannin transmembrane MFS_1 PF07690.16 KXT05014.1 - 1.2e-23 83.6 18.0 1.2e-23 83.6 18.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Methyltransf_2 PF00891.18 KXT05014.1 - 8.2e-18 64.5 0.0 1.7e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 KXT05014.1 - 0.086 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.16 KXT05015.1 - 7.5e-36 123.8 27.1 1e-35 123.3 27.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KXT05015.1 - 3e-06 26.8 3.8 3e-06 26.8 3.8 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB Fungal_trans PF04082.18 KXT05016.1 - 1e-10 41.1 0.7 1.9e-10 40.2 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT05016.1 - 7.3e-07 29.2 6.5 1.4e-06 28.3 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.19 KXT05017.1 - 8.7e-28 97.6 0.0 1.1e-25 90.6 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KXT05017.1 - 3e-06 26.6 0.0 0.047 12.7 0.0 3.1 3 0 0 3 3 3 3 Lycopene cyclase protein SE PF08491.10 KXT05017.1 - 0.00097 18.3 0.0 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase K_oxygenase PF13434.6 KXT05017.1 - 0.033 13.3 0.0 0.06 12.5 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KXT05017.1 - 0.15 12.0 0.0 0.35 10.8 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KXT05017.1 - 0.17 11.1 0.0 0.31 10.2 0.0 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pal1 PF08316.11 KXT05018.1 - 3.4e-08 34.3 0.1 8.5e-08 33.1 0.1 1.6 1 0 0 1 1 1 1 Pal1 cell morphology protein NAD_binding_2 PF03446.15 KXT05020.1 - 4.6e-33 114.6 0.1 8e-33 113.8 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KXT05020.1 - 1.9e-11 44.4 0.1 4.4e-11 43.2 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KXT05020.1 - 2.6e-11 43.7 0.1 5.4e-11 42.7 0.0 1.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_11 PF14833.6 KXT05020.1 - 1.6e-10 41.3 0.1 2.5e-10 40.6 0.1 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Sacchrp_dh_NADP PF03435.18 KXT05020.1 - 2.4e-05 24.6 0.3 7.2e-05 23.1 0.3 1.8 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain OCD_Mu_crystall PF02423.15 KXT05020.1 - 0.00024 20.1 0.1 0.00041 19.4 0.1 1.4 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family UDPG_MGDP_dh_N PF03721.14 KXT05020.1 - 0.00095 18.8 0.3 0.0028 17.2 0.3 1.8 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_10 PF13460.6 KXT05020.1 - 0.0011 18.9 0.2 0.0019 18.1 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H-binding FIST_C PF10442.9 KXT05020.1 - 0.0065 16.4 0.0 4.9 7.1 0.0 2.3 2 0 0 2 2 2 2 FIST C domain PDH PF02153.17 KXT05020.1 - 0.1 11.6 0.5 0.17 10.9 0.5 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase Ham1p_like PF01725.16 KXT05020.1 - 0.11 12.5 0.1 0.29 11.1 0.0 1.8 2 1 0 2 2 2 0 Ham1 family Semialdhyde_dh PF01118.24 KXT05020.1 - 0.13 12.7 0.1 0.31 11.5 0.1 1.6 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Phage_head_chap PF11113.8 KXT05020.1 - 0.15 12.2 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 Head assembly gene product TrkA_N PF02254.18 KXT05020.1 - 0.23 11.7 2.7 0.24 11.7 0.9 2.0 2 1 0 2 2 2 0 TrkA-N domain P34-Arc PF04045.14 KXT05022.1 - 3.6e-110 367.4 0.2 4.6e-110 367.0 0.2 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.12 KXT05022.1 - 0.022 14.4 0.0 0.05 13.2 0.0 1.6 1 0 0 1 1 1 0 ARP2/3 complex 20 kDa subunit (ARPC4) Pro_isomerase PF00160.21 KXT05023.1 - 1.7e-57 194.1 0.2 2e-57 193.9 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pkinase PF00069.25 KXT05024.1 - 4.9e-54 183.5 0.0 6.6e-54 183.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT05024.1 - 1.3e-33 116.4 0.0 1.9e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXT05024.1 - 8.1e-05 22.1 0.0 0.00021 20.7 0.0 1.6 2 0 0 2 2 2 1 Kinase-like FAD_binding_3 PF01494.19 KXT05025.1 - 2.4e-17 63.2 2.7 5.2e-17 62.1 2.7 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXT05025.1 - 1.7e-05 24.2 0.3 0.063 12.5 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KXT05025.1 - 0.00018 20.9 0.0 0.00048 19.5 0.0 1.6 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 KXT05025.1 - 0.00041 19.5 1.9 0.0096 15.0 1.9 2.2 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KXT05025.1 - 0.00094 19.4 0.2 0.0037 17.5 0.2 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 KXT05025.1 - 0.0014 17.8 0.0 0.002 17.2 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Trp_halogenase PF04820.14 KXT05025.1 - 0.0028 16.6 0.1 4.9 5.9 0.0 3.3 4 0 0 4 4 4 2 Tryptophan halogenase DAO PF01266.24 KXT05025.1 - 0.0036 16.9 4.8 1.4 8.4 1.3 2.9 1 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXT05025.1 - 0.036 13.3 0.1 0.37 10.0 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Myosin_N PF02736.19 KXT05025.1 - 0.044 13.6 0.3 0.09 12.6 0.3 1.5 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain GMC_oxred_N PF00732.19 KXT05025.1 - 0.12 11.7 0.0 0.31 10.4 0.0 1.6 1 1 1 2 2 2 0 GMC oxidoreductase FAD_binding_2 PF00890.24 KXT05025.1 - 0.13 11.3 1.8 0.15 11.1 1.0 1.5 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 KXT05025.1 - 0.15 12.1 0.2 15 5.6 0.1 3.0 4 0 0 4 4 4 0 FAD-NAD(P)-binding DUF3024 PF11225.8 KXT05025.1 - 0.29 11.4 0.7 5.4 7.3 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3024) Peptidase_M76 PF09768.9 KXT05026.1 - 7.6e-68 227.6 0.3 1e-67 227.2 0.3 1.2 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 KXT05026.1 - 0.033 14.0 2.0 0.057 13.3 1.4 1.6 1 1 0 1 1 1 0 SprT-like family Peptidase_M91 PF14891.6 KXT05026.1 - 0.075 13.3 0.2 0.11 12.8 0.2 1.2 1 0 0 1 1 1 0 Effector protein MBOAT_2 PF13813.6 KXT05027.1 - 1.8e-14 53.8 6.1 1.8e-14 53.8 6.1 1.8 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family DUF1445 PF07286.12 KXT05028.1 - 1.6e-57 193.5 0.0 2e-57 193.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) Abhydrolase_6 PF12697.7 KXT05029.1 - 1e-13 52.4 0.0 1.2e-13 52.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ank_2 PF12796.7 KXT05031.1 - 2.4e-45 153.0 3.4 4.6e-16 59.2 0.1 4.7 2 1 3 5 5 4 4 Ankyrin repeats (3 copies) SF3b1 PF08920.10 KXT05031.1 - 6.1e-28 97.7 0.7 6.1e-28 97.7 0.7 2.5 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 Ank_4 PF13637.6 KXT05031.1 - 4.8e-24 84.4 0.5 3.6e-07 30.6 0.0 5.4 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXT05031.1 - 4.5e-23 78.8 0.6 0.033 14.7 0.0 7.8 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 KXT05031.1 - 2.7e-16 59.2 11.4 0.0055 17.1 0.0 7.1 7 0 0 7 7 6 5 Ankyrin repeat Ank_5 PF13857.6 KXT05031.1 - 8e-12 45.2 7.8 0.035 14.4 0.0 6.8 1 1 6 7 7 7 4 Ankyrin repeats (many copies) HEAT_EZ PF13513.6 KXT05031.1 - 8.2e-11 42.2 1.6 0.032 14.7 0.0 6.9 7 1 1 8 8 7 2 HEAT-like repeat HEAT PF02985.22 KXT05031.1 - 4.6e-10 38.9 6.5 0.088 13.1 0.1 9.0 10 0 0 10 10 10 1 HEAT repeat HEAT_2 PF13646.6 KXT05031.1 - 8.3e-10 38.9 8.7 0.27 11.7 0.1 9.0 5 3 5 11 11 11 2 HEAT repeats Cnd1 PF12717.7 KXT05031.1 - 2.1e-07 31.1 0.2 0.21 11.6 0.0 6.2 5 2 2 7 7 7 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KXT05031.1 - 1.1e-05 24.2 0.3 0.053 12.1 0.0 3.3 3 1 0 3 3 3 2 Adaptin N terminal region NUC173 PF08161.12 KXT05031.1 - 0.00017 21.3 0.2 1.4 8.6 0.0 4.6 2 1 2 4 4 4 1 NUC173 domain Vac14_Fab1_bd PF12755.7 KXT05031.1 - 0.00021 21.8 0.1 3.2 8.4 0.0 4.9 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 KXT05031.1 - 0.00079 19.4 0.7 0.043 13.7 0.0 3.9 6 0 0 6 6 5 1 Domain of unknown function (DUF3385) UNC45-central PF11701.8 KXT05031.1 - 0.0038 17.2 0.0 0.0098 15.9 0.0 1.6 1 0 0 1 1 1 1 Myosin-binding striated muscle assembly central CLASP_N PF12348.8 KXT05031.1 - 0.004 16.7 0.2 1.2 8.7 0.0 3.4 3 0 0 3 3 3 1 CLASP N terminal DRIM PF07539.12 KXT05031.1 - 0.2 9.9 0.1 7.2 4.8 0.0 2.9 2 1 1 3 3 3 0 Down-regulated in metastasis Ank_2 PF12796.7 KXT05032.1 - 6.8e-46 154.8 3.3 3.1e-16 59.7 0.1 4.7 2 1 3 5 5 4 4 Ankyrin repeats (3 copies) SF3b1 PF08920.10 KXT05032.1 - 6.3e-28 97.7 0.7 6.3e-28 97.7 0.7 2.6 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 Ank_4 PF13637.6 KXT05032.1 - 1.9e-24 85.7 0.4 3.7e-07 30.6 0.0 5.6 2 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXT05032.1 - 2.1e-23 79.8 0.3 0.034 14.7 0.0 7.8 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 KXT05032.1 - 1.3e-16 60.2 11.1 0.0057 17.1 0.0 7.1 7 0 0 7 7 6 5 Ankyrin repeat Ank_5 PF13857.6 KXT05032.1 - 1.5e-12 47.5 7.9 0.035 14.4 0.0 6.7 1 1 6 7 7 7 4 Ankyrin repeats (many copies) HEAT_EZ PF13513.6 KXT05032.1 - 9.6e-11 42.0 1.6 0.033 14.7 0.0 6.9 7 1 1 8 8 7 2 HEAT-like repeat HEAT PF02985.22 KXT05032.1 - 5.7e-10 38.6 6.5 0.09 13.1 0.1 9.0 10 0 0 10 10 10 1 HEAT repeat HEAT_2 PF13646.6 KXT05032.1 - 1e-09 38.6 8.6 0.27 11.7 0.1 8.9 5 3 5 11 11 11 2 HEAT repeats Cnd1 PF12717.7 KXT05032.1 - 2.5e-07 30.9 0.2 0.22 11.6 0.0 6.2 5 2 2 7 7 7 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KXT05032.1 - 1.2e-05 24.0 0.3 0.054 12.0 0.0 3.3 3 1 0 3 3 3 2 Adaptin N terminal region NUC173 PF08161.12 KXT05032.1 - 0.00019 21.2 0.2 1.4 8.5 0.0 4.6 2 1 2 4 4 4 1 NUC173 domain Vac14_Fab1_bd PF12755.7 KXT05032.1 - 0.00024 21.7 0.1 3.3 8.4 0.0 4.9 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 KXT05032.1 - 0.00078 19.4 0.5 0.044 13.7 0.0 3.9 6 0 0 6 6 5 1 Domain of unknown function (DUF3385) UNC45-central PF11701.8 KXT05032.1 - 0.004 17.1 0.0 0.01 15.8 0.0 1.6 1 0 0 1 1 1 1 Myosin-binding striated muscle assembly central CLASP_N PF12348.8 KXT05032.1 - 0.0043 16.6 0.2 1.2 8.6 0.0 3.4 3 0 0 3 3 3 1 CLASP N terminal DRIM PF07539.12 KXT05032.1 - 0.22 9.8 0.1 7.6 4.7 0.0 2.9 2 1 1 3 3 3 0 Down-regulated in metastasis Zn_clus PF00172.18 KXT05034.1 - 7.2e-07 29.2 5.6 2.3e-06 27.6 5.6 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 KXT05035.1 - 2.2e-15 56.7 6.9 0.0095 16.8 0.7 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXT05035.1 - 1.4e-06 28.5 0.7 0.057 13.7 0.1 4.2 2 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KXT05035.1 - 3.2e-05 22.8 4.1 0.025 13.2 0.5 3.2 2 1 0 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KXT05035.1 - 0.034 12.9 0.0 6.3 5.4 0.0 2.8 2 1 1 3 3 3 0 Nup133 N terminal like DUF2844 PF11005.8 KXT05035.1 - 0.11 12.5 0.4 0.27 11.3 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2844) Herpes_U47 PF05467.11 KXT05036.1 - 0.12 10.4 9.9 0.19 9.8 9.9 1.2 1 0 0 1 1 1 0 Herpesvirus glycoprotein U47 PHD_4 PF16866.5 KXT05036.1 - 2.6 8.2 10.4 11 6.2 1.8 3.3 2 0 0 2 2 2 0 PHD-finger PHD PF00628.29 KXT05036.1 - 4.9 7.1 26.4 1.3 9.0 12.3 3.0 2 0 0 2 2 2 0 PHD-finger Herpes_U47 PF05467.11 KXT05037.1 - 0.059 11.5 8.2 0.094 10.8 8.2 1.2 1 0 0 1 1 1 0 Herpesvirus glycoprotein U47 PHD_4 PF16866.5 KXT05037.1 - 2.8 8.1 10.4 12 6.1 1.8 3.3 2 0 0 2 2 2 0 PHD-finger PHD PF00628.29 KXT05037.1 - 5.4 7.0 26.4 1.3 9.0 12.3 3.0 2 0 0 2 2 2 0 PHD-finger Herpes_U47 PF05467.11 KXT05038.1 - 0.059 11.5 8.2 0.094 10.8 8.2 1.2 1 0 0 1 1 1 0 Herpesvirus glycoprotein U47 PHD_4 PF16866.5 KXT05038.1 - 2.8 8.1 10.4 12 6.1 1.8 3.3 2 0 0 2 2 2 0 PHD-finger PHD PF00628.29 KXT05038.1 - 5.4 7.0 26.4 1.3 9.0 12.3 3.0 2 0 0 2 2 2 0 PHD-finger Vps53_N PF04100.12 KXT05039.1 - 5.9e-107 357.9 2.0 5.9e-107 357.9 2.0 1.6 2 0 0 2 2 2 1 Vps53-like, N-terminal Vps54_N PF10475.9 KXT05039.1 - 4.6e-09 36.0 5.3 1.4e-08 34.3 5.5 1.6 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 KXT05039.1 - 3.2e-05 23.8 0.1 9.8e-05 22.2 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) DUF3510 PF12022.8 KXT05039.1 - 0.013 15.9 1.2 1.1 9.7 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3510) Zw10 PF06248.13 KXT05039.1 - 0.015 13.9 3.1 0.034 12.7 3.1 1.5 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 Spc7 PF08317.11 KXT05039.1 - 0.024 13.5 2.6 0.06 12.2 2.6 1.7 1 0 0 1 1 1 0 Spc7 kinetochore protein COG2 PF06148.11 KXT05039.1 - 0.029 14.4 5.3 0.027 14.5 1.3 3.0 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 VPS53_C PF16854.5 KXT05039.1 - 0.052 13.4 0.0 0.31 10.9 0.0 2.1 1 1 1 2 2 2 0 Vacuolar protein sorting-associated protein 53 C-terminus DUF3072 PF11272.8 KXT05039.1 - 0.063 13.2 0.0 2.7 8.0 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3072) Thioesterase PF00975.20 KXT05039.1 - 0.12 12.5 1.9 2.5 8.1 0.0 3.1 3 0 0 3 3 3 0 Thioesterase domain Hrs_helical PF12210.8 KXT05039.1 - 0.16 12.5 5.0 14 6.3 0.0 3.5 3 0 0 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate APG6_N PF17675.1 KXT05039.1 - 0.85 10.2 8.5 0.13 12.8 1.8 2.8 2 1 1 3 3 3 0 Apg6 coiled-coil region FAM76 PF16046.5 KXT05039.1 - 1.1 8.6 3.8 0.53 9.6 0.9 1.9 2 0 0 2 2 2 0 FAM76 protein Baculo_PEP_C PF04513.12 KXT05039.1 - 4.6 7.3 8.4 1.1 9.3 2.9 2.7 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Herpes_U47 PF05467.11 KXT05040.1 - 0.12 10.4 9.9 0.19 9.8 9.9 1.2 1 0 0 1 1 1 0 Herpesvirus glycoprotein U47 PHD_4 PF16866.5 KXT05040.1 - 2.6 8.2 10.4 11 6.2 1.8 3.3 2 0 0 2 2 2 0 PHD-finger PHD PF00628.29 KXT05040.1 - 4.9 7.1 26.4 1.3 9.0 12.3 3.0 2 0 0 2 2 2 0 PHD-finger RTC_insert PF05189.13 KXT05041.1 - 1.9e-30 105.4 0.1 4.2e-30 104.3 0.1 1.6 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.21 KXT05041.1 - 7.2e-28 97.3 0.1 8.9e-28 97.0 0.1 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase Astacin PF01400.24 KXT05042.1 - 7.8e-08 32.2 0.3 1.4e-06 28.0 0.1 2.2 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) AAA PF00004.29 KXT05043.1 - 5e-36 124.1 0.0 8.6e-36 123.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXT05043.1 - 1.6e-06 27.8 0.1 4.5e-06 26.4 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KXT05043.1 - 4.2e-06 26.6 0.0 8.7e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KXT05043.1 - 6.5e-06 26.6 0.3 0.00042 20.7 0.0 2.7 1 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 KXT05043.1 - 4.1e-05 23.6 0.0 0.00011 22.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 KXT05043.1 - 9.1e-05 22.6 0.0 0.00017 21.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 KXT05043.1 - 0.00012 22.6 0.5 0.0011 19.5 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 KXT05043.1 - 0.00015 21.9 0.0 0.00031 20.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KXT05043.1 - 0.00022 21.3 0.2 0.0014 18.7 0.1 2.3 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXT05043.1 - 0.00041 20.6 0.1 0.009 16.3 0.0 2.6 2 1 1 3 3 2 1 AAA domain RNA_helicase PF00910.22 KXT05043.1 - 0.00074 19.9 0.0 0.0033 17.8 0.0 2.2 1 1 0 1 1 1 1 RNA helicase AAA_25 PF13481.6 KXT05043.1 - 0.00079 19.1 0.0 0.04 13.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KXT05043.1 - 0.0011 18.5 0.1 0.0022 17.4 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TniB PF05621.11 KXT05043.1 - 0.0018 17.7 0.0 1.7 8.0 0.0 2.7 1 1 1 2 2 2 2 Bacterial TniB protein IstB_IS21 PF01695.17 KXT05043.1 - 0.0022 17.7 0.0 0.0039 16.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.6 KXT05043.1 - 0.0051 17.1 0.3 0.011 16.0 0.0 1.8 2 0 0 2 2 1 1 AAA domain ABC_tran PF00005.27 KXT05043.1 - 0.0056 17.2 0.0 0.013 16.0 0.0 1.7 1 1 0 1 1 1 1 ABC transporter NACHT PF05729.12 KXT05043.1 - 0.0075 16.2 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_24 PF13479.6 KXT05043.1 - 0.011 15.5 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KXT05043.1 - 0.018 15.0 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain Sigma54_activat PF00158.26 KXT05043.1 - 0.026 14.2 0.0 0.059 13.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain SPT2 PF08243.11 KXT05043.1 - 0.043 14.3 5.6 0.11 13.0 5.6 1.7 1 0 0 1 1 1 0 SPT2 chromatin protein AAA_21 PF13304.6 KXT05043.1 - 0.049 13.4 0.7 4.2 7.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system TsaE PF02367.17 KXT05043.1 - 0.055 13.5 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 KXT05043.1 - 0.06 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Viral_helicase1 PF01443.18 KXT05043.1 - 0.061 13.0 0.0 0.23 11.2 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 KXT05043.1 - 0.064 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 KXT05043.1 - 0.068 13.1 0.0 0.27 11.1 0.0 1.9 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea CPT PF07931.12 KXT05043.1 - 0.075 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein DUF815 PF05673.13 KXT05043.1 - 0.078 12.1 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 KXT05043.1 - 0.087 12.1 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin ATPase PF06745.13 KXT05043.1 - 0.094 12.0 0.0 0.62 9.4 0.0 2.0 1 1 1 2 2 2 0 KaiC TIP49 PF06068.13 KXT05043.1 - 0.096 11.9 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain SKI PF01202.22 KXT05043.1 - 0.11 12.6 0.2 0.46 10.6 0.0 2.2 3 0 0 3 3 2 0 Shikimate kinase Parvo_NS1 PF01057.17 KXT05043.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_17 PF13207.6 KXT05043.1 - 0.12 12.8 0.4 0.35 11.3 0.0 2.0 2 0 0 2 2 1 0 AAA domain Importin_rep_6 PF18829.1 KXT05043.1 - 0.15 12.2 1.4 0.44 10.7 1.4 1.8 1 0 0 1 1 1 0 Importin repeat 6 Lipase_chap PF03280.14 KXT05044.1 - 0.12 12.3 0.4 0.18 11.7 0.4 1.4 1 1 0 1 1 1 0 Proteobacterial lipase chaperone protein Pyrophosphatase PF00719.19 KXT05045.1 - 2.4e-58 196.5 0.1 3.4e-58 196.0 0.1 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase L6_membrane PF05805.12 KXT05046.1 - 0.065 12.8 0.7 0.077 12.6 0.7 1.3 1 0 0 1 1 1 0 L6 membrane protein Ion_trans_2 PF07885.16 KXT05046.1 - 0.53 10.3 0.1 0.53 10.3 0.1 2.2 3 1 0 3 3 3 0 Ion channel RCR PF12273.8 KXT05047.1 - 2.7e-10 40.9 10.1 8.4e-10 39.3 10.1 1.9 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF4336 PF14234.6 KXT05050.1 - 1.6e-15 57.1 0.2 1.2e-11 44.4 0.1 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4336) Myb_DNA-binding PF00249.31 KXT05051.1 - 0.0054 16.9 0.2 0.047 13.9 0.0 2.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain RHS_repeat PF05593.14 KXT05051.1 - 0.85 10.2 5.1 28 5.3 0.1 3.6 2 1 1 3 3 3 0 RHS Repeat DUF2937 PF11157.8 KXT05051.1 - 3.1 7.5 17.0 0.32 10.7 1.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2937) Zn_clus PF00172.18 KXT05052.1 - 2.5e-07 30.7 11.6 4.2e-07 30.0 11.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXT05052.1 - 1.5e-06 27.4 0.1 2.2e-06 26.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cu-oxidase PF00394.22 KXT05068.1 - 6.2e-07 29.7 1.1 1.2e-06 28.7 0.4 1.8 2 0 0 2 2 2 1 Multicopper oxidase Pribosyltran PF00156.27 KXT05069.1 - 0.00011 21.8 0.0 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain LON_substr_bdg PF02190.16 KXT05070.1 - 7.8e-29 101.0 0.0 1.4e-28 100.2 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 KXT05070.1 - 5.7e-10 38.9 21.3 2.2e-08 33.8 10.4 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXT05070.1 - 1.1e-09 37.9 17.9 1.2e-06 28.3 7.8 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KXT05070.1 - 1e-08 35.2 20.3 0.00036 20.6 9.2 2.5 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KXT05070.1 - 2.1e-08 34.1 21.9 1e-05 25.5 4.2 2.9 2 1 1 3 3 3 2 RING-type zinc-finger zf-RING_5 PF14634.6 KXT05070.1 - 2.4e-07 30.6 22.7 0.00033 20.5 8.5 2.4 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4 PF00097.25 KXT05070.1 - 3.4e-07 30.0 20.8 4.6e-05 23.2 9.1 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXT05070.1 - 5.6e-06 26.6 23.8 1.6e-05 25.1 9.3 2.5 2 0 0 2 2 2 2 Ring finger domain Prok-RING_4 PF14447.6 KXT05070.1 - 0.00011 22.0 20.6 0.00045 20.0 7.9 2.5 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 KXT05070.1 - 0.002 18.2 5.0 0.002 18.2 5.0 2.5 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-RING_4 PF14570.6 KXT05070.1 - 0.013 15.3 7.2 0.029 14.1 3.7 2.9 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 KXT05070.1 - 0.03 14.2 11.8 0.6 10.0 3.7 2.5 2 0 0 2 2 2 0 zf-RING of BARD1-type protein U-box PF04564.15 KXT05070.1 - 0.057 13.6 0.0 0.19 11.9 0.0 1.8 2 0 0 2 2 2 0 U-box domain HTH_31 PF13560.6 KXT05070.1 - 0.17 12.2 0.6 0.76 10.2 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain DZR PF12773.7 KXT05070.1 - 2.5 8.2 12.4 4.5 7.4 0.2 3.3 2 1 1 3 3 3 0 Double zinc ribbon 2OG-FeII_Oxy_5 PF13759.6 KXT05071.1 - 0.034 14.6 0.5 0.063 13.7 0.5 1.4 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Reprolysin_2 PF13574.6 KXT05071.1 - 0.13 12.1 1.0 0.17 11.7 1.0 1.1 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like GalKase_gal_bdg PF10509.9 KXT05072.1 - 5.8e-21 73.8 0.0 1e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 KXT05072.1 - 7e-16 58.2 1.5 1.7e-15 57.0 1.5 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KXT05072.1 - 1.8e-15 57.1 0.0 8.8e-15 54.8 0.0 2.1 2 0 0 2 2 2 1 GHMP kinases C terminal Nuc_N PF14448.6 KXT05072.1 - 0.044 13.6 0.7 0.19 11.6 0.1 2.1 2 0 0 2 2 2 0 Nuclease N terminal DUF3139 PF11337.8 KXT05072.1 - 0.047 14.3 0.4 0.11 13.2 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) BTB PF00651.31 KXT05073.1 - 1.6e-07 31.5 0.0 6.8e-07 29.5 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain CRC_subunit PF08624.10 KXT05074.1 - 3.7e-51 173.1 1.2 5.2e-51 172.6 0.1 1.8 2 0 0 2 2 2 1 Chromatin remodelling complex Rsc7/Swp82 subunit Cyclin PF08613.11 KXT05074.1 - 5.5e-12 46.3 0.1 1.2e-11 45.3 0.1 1.6 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KXT05074.1 - 0.00015 21.5 0.0 0.00027 20.7 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain CALM_bind PF16025.5 KXT05074.1 - 0.069 13.6 1.0 0.33 11.4 0.0 2.5 2 0 0 2 2 2 0 Calcium-dependent calmodulin binding 7tm_2 PF00002.24 KXT05075.1 - 5.3e-08 32.5 11.3 2e-07 30.6 11.4 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) Fumarate_red_D PF02313.17 KXT05075.1 - 0.42 10.7 9.8 0.11 12.6 2.3 3.2 4 0 0 4 4 4 0 Fumarate reductase subunit D Glyco_tranf_2_3 PF13641.6 KXT05076.1 - 6.3e-20 72.1 0.1 1e-19 71.4 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KXT05076.1 - 7.6e-08 32.4 0.1 1.6e-07 31.3 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KXT05076.1 - 4.5e-07 29.5 0.0 0.00032 20.2 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 21 Tfb2 PF03849.14 KXT05077.1 - 1.2e-136 455.4 1.2 3.3e-136 453.9 0.2 1.8 2 0 0 2 2 2 1 Transcription factor Tfb2 Tfb2_C PF18307.1 KXT05077.1 - 3.5e-17 62.6 0.2 7e-17 61.6 0.2 1.5 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 KXT05077.1 - 3.5e-05 24.0 0.1 0.0001 22.5 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain adh_short PF00106.25 KXT05078.1 - 5e-33 114.2 0.0 6.9e-33 113.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT05078.1 - 6.9e-22 78.1 0.0 1e-21 77.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT05078.1 - 0.0017 18.3 0.1 0.12 12.3 0.0 2.4 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KXT05078.1 - 0.098 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pkinase PF00069.25 KXT05079.1 - 1.4e-67 227.8 0.0 1.9e-67 227.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT05079.1 - 2.6e-30 105.6 0.0 4e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KXT05079.1 - 1.9e-12 47.7 0.8 1.9e-12 47.7 0.8 2.5 2 0 0 2 2 2 1 Protein kinase C terminal domain C2 PF00168.30 KXT05079.1 - 1.3e-09 38.2 0.0 1.8e-07 31.3 0.0 2.7 2 0 0 2 2 2 1 C2 domain Kinase-like PF14531.6 KXT05079.1 - 1.8e-07 30.8 0.1 4.1e-07 29.6 0.0 1.6 2 0 0 2 2 2 1 Kinase-like MaoC_dehydratas PF01575.19 KXT05079.1 - 6e-07 29.1 0.0 1.3e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KXT05079.1 - 9.2e-06 25.8 0.0 0.00016 21.8 0.0 2.5 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Haspin_kinase PF12330.8 KXT05079.1 - 0.003 16.5 0.1 0.006 15.6 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KXT05079.1 - 0.0049 16.8 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 KXT05079.1 - 0.0075 15.9 0.1 1.4 8.5 0.0 2.4 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 KXT05079.1 - 0.064 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 KXT05079.1 - 0.11 11.8 0.1 0.22 10.9 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4533 PF15047.6 KXT05084.1 - 0.29 10.7 2.0 0.39 10.2 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4533) APH PF01636.23 KXT05085.1 - 0.001 19.1 1.6 0.0014 18.6 0.3 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF3046 PF11248.8 KXT05085.1 - 0.089 13.2 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3046) Peptidase_C12 PF01088.21 KXT05086.1 - 1.5e-46 158.9 0.0 1.8e-46 158.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UQ_con PF00179.26 KXT05087.1 - 7.2e-40 135.9 0.0 8.1e-40 135.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KXT05087.1 - 2.4e-06 27.3 0.0 2.9e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KXT05087.1 - 0.00018 21.8 0.0 0.00022 21.5 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 KXT05087.1 - 0.0064 16.3 0.0 0.01 15.7 0.0 1.2 1 0 0 1 1 1 1 UEV domain F-box PF00646.33 KXT05090.1 - 0.0027 17.5 0.0 0.0048 16.7 0.0 1.4 1 0 0 1 1 1 1 F-box domain DPM3 PF08285.11 KXT05092.1 - 1.1e-35 121.7 0.0 1.2e-35 121.6 0.0 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Vta1_C PF18097.1 KXT05092.1 - 0.12 12.1 0.0 1.8 8.3 0.0 2.3 2 0 0 2 2 2 0 Vta1 C-terminal domain Bap31 PF05529.12 KXT05092.1 - 0.16 11.8 0.0 0.17 11.8 0.0 1.1 1 0 0 1 1 1 0 Bap31/Bap29 transmembrane region Glyco_hydro_3 PF00933.21 KXT05093.1 - 6.5e-64 216.3 0.0 9.2e-64 215.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.25 KXT05093.1 - 2.6e-05 24.5 0.0 0.00023 21.4 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Glyco_hydro_3_C PF01915.22 KXT05093.1 - 0.0046 16.9 0.0 0.009 16.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Abhydrolase_3 PF07859.13 KXT05094.1 - 2.7e-47 161.4 0.1 3.4e-47 161.1 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXT05094.1 - 1.4e-11 44.0 0.0 3e-11 42.9 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_2 PF02230.16 KXT05094.1 - 0.0071 16.2 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 KXT05094.1 - 0.011 16.3 0.5 0.029 15.0 0.3 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KXT05094.1 - 0.038 13.5 0.0 0.063 12.8 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KXT05094.1 - 0.052 13.2 0.0 0.075 12.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXT05094.1 - 0.061 12.2 0.0 6.7 5.5 0.0 2.1 2 0 0 2 2 2 0 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 KXT05094.1 - 0.077 12.2 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Esterase PF00756.20 KXT05094.1 - 0.13 11.9 0.5 4.9 6.7 0.5 2.5 2 1 0 2 2 2 0 Putative esterase APH PF01636.23 KXT05095.1 - 9.5e-38 130.5 0.0 1.5e-37 129.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KXT05095.1 - 4e-05 23.1 0.0 6e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 KXT05095.1 - 6.5e-05 22.6 0.0 9.3e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KXT05095.1 - 8.5e-05 22.2 0.0 0.0035 17.0 0.0 2.3 2 0 0 2 2 2 1 RIO1 family DUF1679 PF07914.11 KXT05095.1 - 0.0049 15.8 0.0 0.011 14.6 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) Fructosamin_kin PF03881.14 KXT05095.1 - 0.032 13.4 0.0 0.26 10.5 0.0 2.1 1 1 0 1 1 1 0 Fructosamine kinase Kdo PF06293.14 KXT05095.1 - 0.098 12.0 0.0 0.37 10.1 0.0 1.9 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRRNT_2 PF08263.12 KXT05096.1 - 0.069 13.5 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain HEAT PF02985.22 KXT05097.1 - 0.021 15.1 1.0 34 5.1 0.1 4.1 3 0 0 3 3 3 0 HEAT repeat TAF6_C PF07571.13 KXT05097.1 - 0.043 14.1 0.0 0.18 12.2 0.0 2.1 2 0 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain UNC45-central PF11701.8 KXT05097.1 - 0.057 13.4 0.1 0.26 11.3 0.0 2.2 2 0 0 2 2 2 0 Myosin-binding striated muscle assembly central RYDR_ITPR PF01365.21 KXT05097.1 - 0.098 12.1 0.1 1.8 7.9 0.0 2.7 3 1 0 3 3 3 0 RIH domain BUD22 PF09073.10 KXT05098.1 - 0.11 11.8 11.0 0.13 11.6 11.0 1.1 1 0 0 1 1 1 0 BUD22 RNA_pol_N PF01194.17 KXT05099.1 - 3.7e-29 100.8 0.7 4.7e-29 100.5 0.7 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit DUF1610 PF07754.11 KXT05099.1 - 0.028 14.4 0.0 0.054 13.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) Pkinase PF00069.25 KXT05100.1 - 2.3e-50 171.4 0.0 2.9e-50 171.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT05100.1 - 2e-31 109.3 0.0 2.4e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXT05100.1 - 0.0046 16.3 0.0 0.01 15.2 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KXT05100.1 - 0.0065 16.4 0.1 0.013 15.4 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KXT05100.1 - 0.012 15.0 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family 5_nucleotid PF05761.14 KXT05100.1 - 0.21 10.4 0.0 0.29 10.0 0.0 1.1 1 0 0 1 1 1 0 5' nucleotidase family Haspin_kinase PF12330.8 KXT05100.1 - 0.23 10.4 0.0 0.33 9.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain FAS_I_H PF18314.1 KXT05101.1 - 1e-80 270.2 0.4 2.9e-80 268.7 0.0 2.0 2 0 0 2 2 2 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 KXT05101.1 - 1.3e-76 256.5 0.0 2.9e-76 255.3 0.0 1.7 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain ketoacyl-synt PF00109.26 KXT05101.1 - 1.1e-19 71.0 0.0 2.1e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 KXT05101.1 - 1.7e-17 63.6 0.0 4.1e-17 62.4 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 KXT05101.1 - 7.6e-11 42.1 0.0 1.9e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 KXT05101.1 - 1.4e-06 27.9 0.0 3.9e-06 26.5 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KXT05101.1 - 0.019 14.9 0.0 0.052 13.5 0.0 1.7 1 0 0 1 1 1 0 KR domain DEC-1_N PF04625.13 KXT05101.1 - 8.8 5.2 12.0 16 4.4 12.0 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Abhydrolase_3 PF07859.13 KXT05102.1 - 1.3e-40 139.5 0.2 3.6e-31 108.7 0.1 2.8 1 1 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXT05102.1 - 3.8e-14 52.4 0.0 6.1e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 KXT05102.1 - 0.0028 16.6 0.0 0.0073 15.2 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family PRKCSH-like PF12999.7 KXT05103.1 - 6.3e-42 143.3 8.4 3.5e-41 140.9 5.0 3.0 1 1 1 2 2 2 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 KXT05103.1 - 5.7e-32 110.5 3.2 1.9e-31 108.8 1.4 2.2 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 KXT05103.1 - 3e-08 34.6 2.3 4.5e-08 34.0 0.7 2.3 2 0 0 2 2 1 1 Glucosidase II beta subunit-like protein Mod_r PF07200.13 KXT05103.1 - 0.0054 16.8 4.7 0.085 13.0 1.8 2.7 2 1 0 2 2 2 1 Modifier of rudimentary (Mod(r)) protein KxDL PF10241.9 KXT05103.1 - 0.0099 16.1 5.8 1.6 9.0 0.1 3.2 3 0 0 3 3 3 2 Uncharacterized conserved protein ATG27 PF09451.10 KXT05103.1 - 0.013 15.4 0.3 0.026 14.4 0.3 1.5 1 0 0 1 1 1 0 Autophagy-related protein 27 Sec8_exocyst PF04048.14 KXT05103.1 - 0.018 15.0 4.6 1.6 8.6 0.8 2.5 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF745 PF05335.13 KXT05103.1 - 0.025 14.3 7.9 0.17 11.6 4.8 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF745) DELLA PF12041.8 KXT05103.1 - 0.1 12.5 0.1 12 5.9 0.0 2.6 2 0 0 2 2 2 0 Transcriptional regulator DELLA protein N terminal OmpH PF03938.14 KXT05103.1 - 0.16 12.3 8.0 1.4 9.3 5.1 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) ApoLp-III PF07464.11 KXT05103.1 - 0.22 11.6 6.5 0.41 10.7 0.4 3.1 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) OEP PF02321.18 KXT05103.1 - 0.36 10.6 0.0 0.36 10.6 0.0 2.8 2 1 1 3 3 3 0 Outer membrane efflux protein UPF0449 PF15136.6 KXT05103.1 - 0.73 10.3 4.9 1.4 9.4 0.1 2.8 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 Spc7 PF08317.11 KXT05103.1 - 1.1 8.1 12.5 3.6 6.4 0.1 2.6 2 1 1 3 3 3 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 KXT05103.1 - 1.2 9.2 14.6 0.56 10.3 0.3 3.1 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein DUF5082 PF16888.5 KXT05103.1 - 1.5 9.1 5.7 0.94 9.8 0.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) DUF349 PF03993.12 KXT05103.1 - 1.5 9.2 8.5 0.54 10.6 4.7 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) SOAR PF16533.5 KXT05103.1 - 1.5 8.8 7.4 3.6 7.6 2.3 3.0 2 1 0 2 2 2 0 STIM1 Orai1-activating region Prefoldin_2 PF01920.20 KXT05103.1 - 1.6 8.7 12.9 7.3 6.6 0.4 3.5 3 0 0 3 3 3 0 Prefoldin subunit MscS_porin PF12795.7 KXT05103.1 - 2.9 7.4 14.0 0.43 10.1 2.3 3.0 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain ATG16 PF08614.11 KXT05103.1 - 3.4 7.9 17.6 0.34 11.1 2.3 3.2 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) KfrA_N PF11740.8 KXT05103.1 - 4.8 7.9 10.7 12 6.6 0.4 3.4 3 0 0 3 3 3 0 Plasmid replication region DNA-binding N-term Gal4_dimer PF03902.13 KXT05103.1 - 5.1 7.3 6.6 24 5.2 6.6 2.2 1 1 0 1 1 1 0 Gal4-like dimerisation domain CENP-F_leu_zip PF10473.9 KXT05103.1 - 5.1 7.1 13.8 6.4 6.8 9.0 2.8 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Jnk-SapK_ap_N PF09744.9 KXT05103.1 - 6 7.1 16.6 0.39 10.9 3.9 3.1 2 1 0 3 3 3 0 JNK_SAPK-associated protein-1 Vps5 PF09325.10 KXT05103.1 - 7.8 6.0 11.8 0.32 10.5 2.8 2.6 3 0 0 3 3 3 0 Vps5 C terminal like adh_short_C2 PF13561.6 KXT05104.1 - 1.3e-47 162.4 0.0 1.8e-47 161.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXT05104.1 - 2e-39 135.1 0.0 3.4e-39 134.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXT05104.1 - 2e-10 40.9 0.0 2.7e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 KR domain AMP-binding PF00501.28 KXT05105.1 - 4.7e-222 737.1 0.0 1.1e-81 274.6 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 KXT05105.1 - 1.6e-189 630.4 0.0 7.4e-35 120.5 0.0 7.2 6 1 1 7 7 7 6 Condensation domain PP-binding PF00550.25 KXT05105.1 - 1.5e-61 204.7 13.1 4.9e-12 46.0 0.2 6.9 6 0 0 6 6 6 6 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KXT05105.1 - 3.4e-12 47.2 0.0 0.0055 17.7 0.0 4.2 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain Transferase PF02458.15 KXT05105.1 - 7.5e-09 34.7 0.0 0.019 13.7 0.0 4.3 4 0 0 4 4 4 2 Transferase family GNAT_acetyltr_2 PF13718.6 KXT05105.1 - 0.0014 18.1 0.0 0.0037 16.7 0.0 1.6 1 0 0 1 1 1 1 GNAT acetyltransferase 2 WES_acyltransf PF03007.16 KXT05105.1 - 0.0022 17.8 0.1 0.52 10.0 0.0 3.6 3 0 0 3 3 3 1 Wax ester synthase-like Acyl-CoA acyltransferase domain FoP_duplication PF13865.6 KXT05106.1 - 0.87 10.2 5.5 50 4.5 0.0 2.4 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 Ldh_2 PF02615.14 KXT05107.1 - 1.4e-120 402.5 0.4 1.6e-120 402.3 0.4 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase R3H PF01424.22 KXT05108.1 - 1.9e-10 40.5 0.1 6e-10 39.0 0.0 1.9 2 0 0 2 2 2 1 R3H domain zf-H2C2_2 PF13465.6 KXT05108.1 - 7.9e-07 29.2 8.1 0.00017 21.9 1.3 3.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KXT05108.1 - 4.8e-06 26.7 7.6 0.0021 18.4 0.9 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXT05108.1 - 2.3e-05 24.9 4.1 0.0013 19.4 0.4 3.0 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KXT05108.1 - 0.1 12.7 0.2 0.34 11.0 0.2 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KXT05108.1 - 0.15 12.7 1.0 0.66 10.7 0.1 2.3 3 0 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-CCHC_2 PF13696.6 KXT05108.1 - 0.25 11.2 4.4 0.65 9.9 1.0 2.4 2 0 0 2 2 2 0 Zinc knuckle K_oxygenase PF13434.6 KXT05109.1 - 3.7e-104 348.6 0.0 4.4e-104 348.3 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KXT05109.1 - 4.1e-08 32.8 0.0 3e-07 30.0 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXT05109.1 - 5.6e-07 29.1 0.1 1.4e-05 24.5 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXT05109.1 - 1.6e-05 24.9 0.3 4.6e-05 23.4 0.0 2.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding TPR_1 PF00515.28 KXT05110.1 - 2.3e-16 58.8 6.5 1.2e-06 28.1 0.0 4.8 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 KXT05110.1 - 1.6e-15 55.9 4.5 3.1e-05 23.7 0.0 5.0 4 0 0 4 4 4 4 Tetratricopeptide repeat PB1 PF00564.24 KXT05110.1 - 5.7e-12 45.4 0.1 1.1e-11 44.5 0.1 1.4 1 0 0 1 1 1 1 PB1 domain TPR_8 PF13181.6 KXT05110.1 - 2e-10 40.0 1.3 0.0014 18.6 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KXT05110.1 - 2.3e-09 37.4 0.4 7.1e-06 26.2 0.0 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 KXT05110.1 - 1.8e-07 31.3 0.2 7 7.5 0.0 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXT05110.1 - 2.8e-07 30.1 4.8 0.0008 19.3 0.1 5.1 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXT05110.1 - 1.6e-06 27.7 1.8 0.00021 20.9 0.1 3.6 2 1 1 3 3 3 1 TPR repeat TPR_16 PF13432.6 KXT05110.1 - 0.00023 21.7 6.4 0.0073 16.9 0.0 4.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXT05110.1 - 0.0099 16.0 3.2 0.25 11.5 0.0 3.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KXT05110.1 - 0.02 14.8 0.6 2.8 7.9 0.1 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXT05110.1 - 0.024 15.4 6.3 2.6 9.1 0.0 4.6 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 KXT05110.1 - 0.083 13.3 0.2 6.7 7.3 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat p450 PF00067.22 KXT05112.1 - 1.3e-68 231.9 0.0 1.7e-68 231.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.28 KXT05113.1 - 1.7e-86 290.5 0.0 2.2e-86 290.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXT05113.1 - 1.3e-10 42.1 0.1 2.8e-10 41.0 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ILVD_EDD PF00920.21 KXT05114.1 - 1.4e-152 508.9 0.0 1.6e-152 508.7 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family Amidohydro_1 PF01979.20 KXT05115.1 - 4.7e-16 59.0 0.0 8.2e-16 58.2 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KXT05115.1 - 1.8e-11 44.2 0.0 7e-08 32.4 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family zf-RING_4 PF14570.6 KXT05115.1 - 3.7e-06 26.6 10.1 6.6e-06 25.8 10.1 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 KXT05115.1 - 9.6e-06 25.8 11.4 1.6e-05 25.1 11.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KXT05115.1 - 0.00044 20.0 10.8 0.00067 19.5 9.3 1.9 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXT05115.1 - 0.00078 19.3 11.6 0.0013 18.5 11.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXT05115.1 - 0.0012 19.1 10.3 0.0021 18.3 10.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KXT05115.1 - 0.0014 18.4 10.8 0.0027 17.5 10.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXT05115.1 - 0.0027 17.7 9.8 0.0056 16.7 9.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KXT05115.1 - 0.02 14.9 5.4 0.046 13.8 5.4 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-UDP PF14569.6 KXT05115.1 - 0.052 13.7 5.5 0.12 12.5 5.5 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4_4 PF15227.6 KXT05115.1 - 0.095 12.9 12.9 0.17 12.1 12.9 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Gemini_AL2 PF01440.16 KXT05115.1 - 0.29 11.6 1.4 0.53 10.7 1.4 1.3 1 0 0 1 1 1 0 Geminivirus AL2 protein zf-RING_5 PF14634.6 KXT05115.1 - 0.37 10.8 9.6 0.77 9.8 9.6 1.6 1 0 0 1 1 1 0 zinc-RING finger domain WD40 PF00400.32 KXT05116.1 - 1.3e-08 35.4 4.4 0.056 14.3 0.0 6.4 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXT05116.1 - 0.01 16.1 0.0 94 3.4 0.0 4.7 4 1 1 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KXT05116.1 - 0.019 14.9 0.1 19 5.3 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KXT05116.1 - 0.12 11.0 0.0 0.26 9.9 0.0 1.5 1 0 0 1 1 1 0 Nucleoporin Nup120/160 DUF1729 PF08354.10 KXT05118.1 - 8.5e-161 534.7 0.0 1.8e-160 533.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 KXT05118.1 - 9.6e-90 301.3 0.0 2.5e-89 299.9 0.0 1.7 1 0 0 1 1 1 1 Acyl transferase domain FAS_meander PF17951.1 KXT05118.1 - 3e-52 176.3 0.0 7.5e-52 175.0 0.0 1.8 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain SAT PF16073.5 KXT05118.1 - 2e-39 135.8 0.0 4.8e-39 134.5 0.0 1.7 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydratas PF01575.19 KXT05118.1 - 6e-36 122.7 0.0 1.5e-35 121.4 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain FAS_N PF17828.1 KXT05118.1 - 2.5e-35 121.3 0.1 9.6e-35 119.4 0.1 2.1 2 0 0 2 2 2 1 N-terminal domain in fatty acid synthase subunit beta MaoC_dehydrat_N PF13452.6 KXT05118.1 - 1.9e-22 79.8 0.0 5.8e-22 78.2 0.0 1.9 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase TIMELESS PF04821.14 KXT05119.1 - 4.1e-90 301.8 2.1 4.1e-90 301.8 2.1 2.4 3 0 0 3 3 3 1 Timeless protein TIMELESS_C PF05029.13 KXT05119.1 - 7.6e-23 81.5 41.3 7.6e-23 81.5 41.3 3.0 2 1 0 2 2 2 1 Timeless protein C terminal region DUF3990 PF13151.6 KXT05120.1 - 0.022 14.4 0.0 0.76 9.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3990) NmrA PF05368.13 KXT05120.1 - 0.16 11.5 0.0 2.1 7.8 0.0 2.1 2 0 0 2 2 2 0 NmrA-like family Roughex PF06020.11 KXT05124.1 - 1.3 8.0 4.4 1.1 8.3 2.3 1.8 2 0 0 2 2 2 0 Drosophila roughex protein tRNA-synt_1g PF09334.11 KXT05125.1 - 0.016 13.9 0.1 0.079 11.7 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (M) DUF3724 PF12521.8 KXT05127.1 - 0.089 12.7 0.2 0.18 11.7 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3724) CBFD_NFYB_HMF PF00808.23 KXT05128.1 - 1.2e-13 51.1 4.1 8.9e-13 48.3 4.1 2.1 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXT05128.1 - 0.00055 20.3 0.5 0.0014 19.0 0.0 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Baculo_LEF-11 PF06385.12 KXT05128.1 - 0.028 14.9 0.0 0.035 14.6 0.0 1.2 1 0 0 1 1 1 0 Baculovirus LEF-11 protein TFIID-18kDa PF02269.16 KXT05128.1 - 0.077 13.0 0.1 0.18 11.8 0.1 1.6 1 1 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Phage_tail_X PF05489.12 KXT05128.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Phage Tail Protein X RNase_H PF00075.24 KXT05129.1 - 2.1e-12 47.4 0.0 3.7e-12 46.6 0.0 1.4 1 1 0 1 1 1 1 RNase H adh_short PF00106.25 KXT05130.1 - 2.4e-41 141.3 0.0 2.9e-41 141.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT05130.1 - 1.1e-31 110.2 0.0 1.2e-31 110.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT05130.1 - 1.5e-13 51.1 0.1 2.1e-13 50.6 0.1 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXT05130.1 - 0.0054 15.9 0.0 0.0072 15.5 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KXT05130.1 - 0.062 12.7 0.1 0.33 10.4 0.1 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Vps35 PF03635.17 KXT05132.1 - 0 1024.1 0.1 0 1023.9 0.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Glyco_hydro_18 PF00704.28 KXT05133.1 - 1.1e-19 71.3 1.2 2.5e-19 70.2 1.2 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Seipin PF06775.14 KXT05134.1 - 1e-60 205.3 0.3 1.3e-60 204.9 0.3 1.2 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) QCR10 PF09796.9 KXT05134.1 - 0.58 10.2 5.1 1.9 8.6 0.2 2.4 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) 3HCDH_N PF02737.18 KXT05135.1 - 5.7e-55 186.0 0.6 7.5e-55 185.6 0.6 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KXT05135.1 - 3.4e-32 110.9 0.0 8e-32 109.7 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Sacchrp_dh_NADP PF03435.18 KXT05135.1 - 0.00069 19.9 0.1 0.0013 19.0 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Pyr_redox_2 PF07992.14 KXT05135.1 - 0.0013 18.1 0.0 0.0018 17.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KXT05135.1 - 0.0017 17.7 0.1 0.0034 16.8 0.1 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KXT05135.1 - 0.003 17.7 0.3 0.0077 16.4 0.3 1.7 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox PF00070.27 KXT05135.1 - 0.018 15.6 0.1 0.04 14.5 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 KXT05135.1 - 0.024 14.2 0.2 0.065 12.8 0.2 1.7 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.24 KXT05135.1 - 0.029 14.0 0.8 0.043 13.4 0.8 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase F420_oxidored PF03807.17 KXT05135.1 - 0.12 12.9 1.5 0.53 10.9 1.1 2.4 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent MFS_1 PF07690.16 KXT05136.1 - 2.6e-23 82.5 81.0 2.1e-22 79.6 54.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily CFEM PF05730.11 KXT05137.1 - 1.4e-05 25.0 0.5 1.4e-05 25.0 0.5 4.2 5 0 0 5 5 5 1 CFEM domain Acyl-CoA_dh_1 PF00441.24 KXT05138.1 - 2.4e-23 83.0 0.8 3.9e-23 82.3 0.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KXT05138.1 - 6e-14 52.7 0.0 1.3e-13 51.5 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KXT05138.1 - 1.5e-08 34.7 0.0 8.5e-08 32.3 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KXT05138.1 - 4.5e-06 27.0 0.0 7e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain ABC_membrane PF00664.23 KXT05139.1 - 5.6e-79 265.6 26.5 3.9e-44 151.4 12.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KXT05139.1 - 2e-61 206.5 0.0 6.2e-32 111.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KXT05139.1 - 5.5e-12 45.6 0.2 0.0028 17.1 0.0 4.0 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KXT05139.1 - 1.2e-09 38.4 0.6 0.33 10.7 0.0 4.2 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system ABC_ATPase PF09818.9 KXT05139.1 - 1e-07 31.2 3.8 0.00094 18.1 0.0 3.2 3 0 0 3 3 3 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 KXT05139.1 - 7.6e-06 25.9 0.0 0.086 12.7 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KXT05139.1 - 2.4e-05 24.0 0.8 0.11 12.3 0.2 3.3 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KXT05139.1 - 0.00012 22.4 0.3 1.2 9.4 0.2 3.7 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KXT05139.1 - 0.00043 19.9 0.5 1.3 8.6 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KXT05139.1 - 0.0022 18.4 1.9 2.9 8.2 0.2 3.6 2 2 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 KXT05139.1 - 0.0023 18.5 0.0 3.7 8.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KXT05139.1 - 0.0056 16.4 0.5 1.6 8.4 0.0 3.2 4 0 0 4 4 4 1 AAA domain AAA_15 PF13175.6 KXT05139.1 - 0.01 15.6 0.0 0.29 10.8 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain DUF87 PF01935.17 KXT05139.1 - 0.031 14.4 0.5 0.4 10.7 0.8 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_7 PF12775.7 KXT05139.1 - 0.042 13.4 0.0 5.6 6.4 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF1335 PF07056.11 KXT05139.1 - 0.045 13.9 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1335) AAA_28 PF13521.6 KXT05139.1 - 0.091 13.0 0.0 6.7 6.9 0.0 3.0 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KXT05139.1 - 0.12 11.7 0.0 3.5 6.9 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin SbcCD_C PF13558.6 KXT05139.1 - 0.2 11.9 5.6 18 5.7 0.3 4.1 3 2 0 3 3 3 0 Putative exonuclease SbcCD, C subunit YuiB PF14068.6 KXT05139.1 - 0.45 11.1 4.2 1.7 9.2 0.2 3.4 3 0 0 3 3 3 0 Putative membrane protein Actin PF00022.19 KXT05140.1 - 1.3e-83 280.9 0.0 3e-82 276.4 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KXT05140.1 - 0.0085 14.9 0.0 0.059 12.2 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 KXT05140.1 - 0.16 12.4 0.0 0.51 10.8 0.0 1.8 1 1 0 1 1 1 0 Cell division protein FtsA F-box PF00646.33 KXT05141.1 - 1e-08 34.8 0.2 1.9e-08 33.9 0.2 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXT05141.1 - 8.8e-07 28.7 0.1 1.4e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 F-box-like Pkinase PF00069.25 KXT05142.1 - 3.1e-53 180.8 0.1 4.8e-53 180.2 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT05142.1 - 1.2e-25 90.3 0.1 1.6e-24 86.6 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KXT05142.1 - 0.00024 21.1 0.0 0.0016 18.4 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KXT05142.1 - 0.0072 15.3 0.0 0.011 14.8 0.0 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 KXT05142.1 - 0.049 13.2 1.0 0.32 10.6 1.0 2.0 1 1 0 1 1 1 0 RIO1 family MFS_1 PF07690.16 KXT05143.1 - 3.4e-24 85.4 76.3 1.1e-17 64.1 44.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4286 PF14114.6 KXT05145.1 - 0.0013 19.1 0.2 1.8 9.1 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4286) EthD PF07110.11 KXT05145.1 - 0.0092 17.1 1.0 3.8 8.7 0.1 2.5 2 0 0 2 2 2 2 EthD domain DNA_pol3_tau_4 PF12168.8 KXT05145.1 - 0.16 12.5 3.1 7.1 7.3 0.1 2.5 2 0 0 2 2 2 0 DNA polymerase III subunits tau domain IV DnaB-binding Mvb12 PF09452.10 KXT05145.1 - 0.44 11.0 3.9 9.8 6.7 0.8 3.2 2 1 1 3 3 3 0 ESCRT-I subunit Mvb12 PRELI PF04707.14 KXT05160.1 - 4.8e-22 78.5 0.1 1.4e-19 70.4 0.0 2.2 2 0 0 2 2 2 2 PRELI-like family Cu_amine_oxid PF01179.20 KXT05163.1 - 1.2e-118 396.7 1.0 1.6e-118 396.2 1.0 1.2 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 KXT05163.1 - 1.3e-19 69.7 0.0 3.7e-19 68.3 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) COX4 PF02936.14 KXT05163.1 - 0.015 15.3 0.1 0.031 14.3 0.1 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV Sfi1 PF08457.10 KXT05164.1 - 4.3e-127 425.1 90.1 2.2e-125 419.4 80.0 2.1 1 1 1 2 2 2 2 Sfi1 spindle body protein LPD11 PF18824.1 KXT05164.1 - 0.12 12.4 0.3 0.4 10.8 0.0 2.0 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 11 Archease PF01951.16 KXT05164.1 - 0.37 11.0 1.9 1.8 8.8 0.1 2.9 3 0 0 3 3 3 0 Archease protein family (MTH1598/TM1083) PCM1_C PF15717.5 KXT05165.1 - 0.091 11.4 0.0 0.094 11.4 0.0 1.1 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus adh_short PF00106.25 KXT05166.1 - 8.2e-39 133.1 0.2 1.6e-38 132.1 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT05166.1 - 7.2e-29 101.0 0.0 1.1e-28 100.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT05166.1 - 6.9e-10 39.1 0.6 1.7e-09 37.9 0.6 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXT05166.1 - 0.0099 15.4 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 KXT05167.1 - 2.3e-20 72.9 0.1 6.6e-20 71.4 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.19 KXT05167.1 - 1.7e-17 63.7 0.0 2.6e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain ADH_N_2 PF16884.5 KXT05167.1 - 1.7e-13 50.4 0.0 3.1e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase DAO PF01266.24 KXT05167.1 - 3.7e-06 26.8 0.1 0.0039 16.8 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXT05167.1 - 1.8e-05 24.2 0.2 0.12 11.6 0.0 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXT05167.1 - 0.0022 18.2 0.1 0.014 15.6 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain ADH_zinc_N_2 PF13602.6 KXT05167.1 - 0.0026 18.8 0.0 0.0059 17.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Trp_halogenase PF04820.14 KXT05167.1 - 0.016 14.1 0.0 0.41 9.4 0.0 2.3 2 1 1 3 3 3 0 Tryptophan halogenase SE PF08491.10 KXT05167.1 - 0.04 13.0 0.0 0.086 11.9 0.0 1.5 1 0 0 1 1 1 0 Squalene epoxidase NAD_binding_9 PF13454.6 KXT05167.1 - 0.042 13.8 0.1 0.59 10.1 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding N2227 PF07942.12 KXT05167.1 - 0.16 11.1 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 N2227-like protein ThiS PF02597.20 KXT05168.1 - 8.2e-08 32.8 0.1 2.1e-07 31.5 0.1 1.6 1 1 0 1 1 1 1 ThiS family Spo12 PF05032.12 KXT05170.1 - 0.038 13.9 0.0 0.069 13.1 0.0 1.5 1 0 0 1 1 1 0 Spo12 family COX_ARM PF06481.14 KXT05171.1 - 0.15 12.0 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 COX Aromatic Rich Motif UPF0560 PF10577.9 KXT05171.1 - 6 5.2 10.7 0.24 9.9 3.3 1.9 1 1 0 2 2 2 0 Uncharacterised protein family UPF0560 EAF PF09816.9 KXT05172.1 - 1.4e-10 41.5 0.0 2.5e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor DUF2981 PF11200.8 KXT05172.1 - 1.8 8.2 5.0 3 7.5 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) His_Phos_1 PF00300.22 KXT05174.1 - 1.9e-28 99.5 0.6 2.9e-27 95.6 0.6 2.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 KXT05174.1 - 3.9e-05 23.2 0.0 6.6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) P5-ATPase PF12409.8 KXT05174.1 - 0.011 15.8 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 P5-type ATPase cation transporter NAT PF04768.13 KXT05175.1 - 4.7e-51 172.8 0.0 2.6e-50 170.4 0.0 2.2 3 0 0 3 3 3 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Glyco_hydro_76 PF03663.14 KXT05176.1 - 1.7e-107 360.1 15.1 3.3e-107 359.2 15.1 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 DUF1168 PF06658.12 KXT05177.1 - 5.2e-39 133.2 11.7 7.4e-39 132.7 11.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) Lyase_catalyt PF09093.11 KXT05177.1 - 0.01 15.0 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 0 Lyase, catalytic PPL5 PF18168.1 KXT05177.1 - 0.9 8.8 5.2 1.3 8.3 5.2 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Presenilin PF01080.17 KXT05177.1 - 2.4 6.8 5.1 2.2 7.0 5.1 1.1 1 0 0 1 1 1 0 Presenilin Casc1_N PF15927.5 KXT05177.1 - 6.2 6.5 17.3 8.3 6.0 17.3 1.2 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Toxin_37 PF11415.8 KXT05178.1 - 0.0096 15.7 3.4 0.0096 15.7 3.4 2.8 2 1 1 3 3 3 1 Antifungal peptide termicin SNF2_N PF00176.23 KXT05179.1 - 3.1e-59 200.5 1.1 5e-59 199.8 1.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXT05179.1 - 7.1e-14 52.1 0.0 1.5e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 KXT05179.1 - 6.4e-09 35.5 2.5 1.1e-08 34.7 2.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXT05179.1 - 1.8e-06 27.9 2.4 4.1e-06 26.7 2.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KXT05179.1 - 2.4e-06 27.3 4.6 5e-06 26.3 4.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXT05179.1 - 3.9e-06 26.6 8.2 1.2e-05 25.0 8.2 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 KXT05179.1 - 1.1e-05 25.5 0.1 1.1e-05 25.5 0.1 2.7 3 0 0 3 3 2 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.6 KXT05179.1 - 5.9e-05 23.3 4.6 0.00013 22.2 4.6 1.7 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KXT05179.1 - 0.0012 18.7 2.5 0.0033 17.3 2.5 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KXT05179.1 - 0.0021 18.0 4.0 0.0049 16.8 4.0 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KXT05179.1 - 0.0053 16.9 5.5 0.011 15.8 5.5 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KXT05179.1 - 0.0054 16.5 5.8 0.017 14.9 5.9 1.9 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf_Rg PF17915.1 KXT05179.1 - 0.091 12.2 0.7 0.25 10.8 0.7 1.7 1 0 0 1 1 1 0 Reverse gyrase zinc finger DZR PF12773.7 KXT05179.1 - 0.6 10.2 5.2 1.4 9.0 5.2 1.6 1 0 0 1 1 1 0 Double zinc ribbon PCI PF01399.27 KXT05180.1 - 3.2e-12 46.9 0.0 5.9e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 PCI domain p450 PF00067.22 KXT05181.1 - 1.4e-44 152.6 0.0 4.2e-44 151.1 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 ERK-JNK_inhib PF15002.6 KXT05181.1 - 0.11 12.2 0.1 0.17 11.6 0.1 1.2 1 0 0 1 1 1 0 ERK and JNK pathways, inhibitor PALP PF00291.25 KXT05182.1 - 7.9e-63 212.6 0.7 1.1e-62 212.2 0.7 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme SAD_SRA PF02182.17 KXT05183.1 - 1.6e-25 89.6 0.0 3.4e-25 88.6 0.0 1.5 1 0 0 1 1 1 1 SAD/SRA domain Dus PF01207.17 KXT05184.1 - 4.8e-37 127.7 0.0 1.1e-26 93.7 0.0 2.7 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) Antifungal_prot PF11402.8 KXT05184.1 - 0.17 12.2 0.9 0.51 10.6 0.9 1.8 1 0 0 1 1 1 0 Antifungal protein zf_CCCH_4 PF18345.1 KXT05184.1 - 0.27 11.4 13.2 0.3 11.2 2.7 3.3 3 0 0 3 3 3 0 Zinc finger domain zf-CCCH_4 PF18044.1 KXT05184.1 - 0.43 10.4 12.9 0.12 12.2 0.5 3.1 3 0 0 3 3 3 0 CCCH-type zinc finger zf-CCCH PF00642.24 KXT05184.1 - 2.9 7.9 5.1 11 6.1 0.1 3.0 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF917 PF06032.12 KXT05185.1 - 1.6e-121 405.4 0.2 7.3e-121 403.3 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.18 KXT05185.1 - 1.6e-31 109.7 7.5 5.9e-30 104.5 1.4 3.1 2 1 1 3 3 3 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KXT05185.1 - 2.7e-29 102.2 0.8 1.3e-26 93.4 0.1 2.8 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.6 KXT05185.1 - 8.1e-07 28.0 2.6 0.017 13.8 0.2 3.0 3 0 0 3 3 3 2 MutL protein BcrAD_BadFG PF01869.20 KXT05185.1 - 0.00027 20.5 0.2 0.00027 20.5 0.2 3.3 3 1 1 4 4 4 1 BadF/BadG/BcrA/BcrD ATPase family ROK PF00480.20 KXT05185.1 - 0.013 15.0 0.1 0.045 13.2 0.1 2.0 1 0 0 1 1 1 0 ROK family StbA PF06406.11 KXT05185.1 - 0.061 12.6 0.0 3.5 6.8 0.0 2.9 3 0 0 3 3 3 0 StbA protein FtsA PF14450.6 KXT05185.1 - 2.2 8.7 11.2 27 5.3 0.0 4.1 3 1 1 4 4 4 0 Cell division protein FtsA SnoaL_4 PF13577.6 KXT05186.1 - 0.035 14.2 0.0 5.9 7.0 0.0 2.2 2 0 0 2 2 2 0 SnoaL-like domain Transferase PF02458.15 KXT05186.1 - 0.07 11.8 0.1 0.087 11.5 0.1 1.1 1 0 0 1 1 1 0 Transferase family Lumazine_bd_2 PF12893.7 KXT05186.1 - 0.095 13.4 0.0 2.3 8.9 0.0 2.6 2 1 0 2 2 2 0 Putative lumazine-binding DUF5103 PF17116.5 KXT05186.1 - 0.17 11.1 0.0 0.29 10.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5103) WD40 PF00400.32 KXT05187.1 - 2e-07 31.6 4.5 0.042 14.7 0.0 4.4 4 1 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXT05187.1 - 0.0018 18.6 0.0 2.8 8.3 0.0 2.8 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain DUF3822 PF12864.7 KXT05187.1 - 0.14 11.3 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3822) PCRF PF03462.18 KXT05188.1 - 1.4e-50 171.8 1.7 1.5e-50 171.7 0.0 1.9 3 0 0 3 3 3 1 PCRF domain RF-1 PF00472.20 KXT05188.1 - 1.2e-33 115.5 7.3 2e-33 114.8 2.1 2.9 3 0 0 3 3 3 1 RF-1 domain VIT1 PF01988.19 KXT05189.1 - 1.2e-58 198.5 1.2 1.5e-58 198.2 1.2 1.1 1 0 0 1 1 1 1 VIT family FA_hydroxylase PF04116.13 KXT05193.1 - 8.8e-25 87.6 14.3 7.5e-24 84.6 11.5 2.1 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily p450 PF00067.22 KXT05195.1 - 3.2e-47 161.3 0.0 2e-46 158.7 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Ysc84 PF04366.12 KXT05196.1 - 5.4e-49 165.2 0.1 1e-48 164.3 0.1 1.5 1 0 0 1 1 1 1 Las17-binding protein actin regulator Amidase PF01425.21 KXT05198.1 - 3.4e-69 234.0 0.0 9.6e-69 232.5 0.0 1.6 1 1 0 1 1 1 1 Amidase DUF5337 PF17272.2 KXT05199.1 - 0.092 12.6 1.0 0.34 10.8 1.0 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5337) tRNA-synt_2 PF00152.20 KXT05200.1 - 5.3e-62 209.7 0.0 6.9e-62 209.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KXT05200.1 - 2e-09 37.3 0.0 4e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KXT05200.1 - 0.0002 20.9 0.1 0.043 13.3 0.0 2.9 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) SUR7 PF06687.12 KXT05201.1 - 9e-13 48.3 5.2 9e-13 48.3 5.2 1.6 1 1 1 2 2 2 1 SUR7/PalI family Tmemb_40 PF10160.9 KXT05201.1 - 0.00049 19.6 0.4 0.00049 19.6 0.4 1.6 2 0 0 2 2 2 1 Predicted membrane protein Claudin_3 PF06653.11 KXT05201.1 - 0.014 15.3 0.3 0.014 15.3 0.3 2.2 2 1 0 2 2 2 0 Tight junction protein, Claudin-like 7TM_GPCR_Srv PF10323.9 KXT05201.1 - 0.051 12.9 0.2 0.051 12.9 0.2 1.4 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv TMEM52 PF14979.6 KXT05201.1 - 0.064 13.2 1.8 0.16 11.9 0.0 2.4 3 0 0 3 3 3 0 Transmembrane 52 DUF898 PF05987.13 KXT05201.1 - 0.085 11.9 3.2 0.037 13.1 0.5 1.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF898) TMEM51 PF15345.6 KXT05201.1 - 0.14 12.0 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 DHHC PF01529.20 KXT05201.1 - 4.4 7.4 9.3 3.5 7.7 2.9 2.6 2 1 1 3 3 3 0 DHHC palmitoyltransferase EphA2_TM PF14575.6 KXT05201.1 - 7.1 7.6 7.4 4.9 8.1 0.0 3.0 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain CNOT1_HEAT_N PF16419.5 KXT05202.1 - 0.0073 16.0 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat Peptidase_M20 PF01546.28 KXT05205.1 - 1.4e-19 70.6 0.1 3.4e-15 56.3 0.1 2.3 2 0 0 2 2 2 2 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KXT05205.1 - 1.1e-15 57.5 0.2 1.9e-15 56.7 0.2 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KXT05205.1 - 0.00044 20.0 0.0 0.0014 18.3 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M42 PF05343.14 KXT05205.1 - 0.1 11.6 0.1 0.63 9.0 0.1 2.0 1 1 1 2 2 2 0 M42 glutamyl aminopeptidase Rad51 PF08423.11 KXT05207.1 - 7.9e-07 28.6 0.1 1.7e-06 27.5 0.1 1.6 1 1 0 1 1 1 1 Rad51 Ino80_Iec3 PF14612.6 KXT05207.1 - 0.096 13.3 0.1 0.15 12.7 0.1 1.2 1 0 0 1 1 1 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling Histidinol_dh PF00815.20 KXT05208.1 - 2.2e-157 524.3 3.9 2.2e-157 524.3 3.9 1.7 2 1 1 3 3 3 1 Histidinol dehydrogenase PRA-CH PF01502.18 KXT05208.1 - 2.3e-24 85.0 0.8 4.2e-24 84.2 0.8 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 KXT05208.1 - 9.5e-15 54.8 0.3 3.8e-14 52.9 0.2 2.2 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG-like PF12643.7 KXT05208.1 - 0.07 13.4 0.2 0.17 12.1 0.2 1.6 1 0 0 1 1 1 0 MazG-like family MazG PF03819.17 KXT05208.1 - 0.072 13.3 0.5 0.21 11.8 0.3 1.9 2 0 0 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain Pro_isomerase PF00160.21 KXT05209.1 - 3.2e-35 121.7 0.0 4.8e-35 121.2 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 KXT05209.1 - 7.5e-16 57.7 0.0 1.5e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) p450 PF00067.22 KXT05210.1 - 1.6e-36 126.0 0.0 3.6e-36 124.9 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 CCDC92 PF14916.6 KXT05210.1 - 0.2 11.5 0.1 15 5.4 0.0 2.5 2 0 0 2 2 2 0 Coiled-coil domain of unknown function ECH_1 PF00378.20 KXT05211.1 - 4.6e-39 134.2 0.0 6.2e-39 133.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXT05211.1 - 1.5e-24 87.1 0.1 2.7e-22 79.7 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Transp_cyt_pur PF02133.15 KXT05212.1 - 8.5e-99 331.3 32.7 9.8e-99 331.1 32.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MRP-L20 PF12824.7 KXT05213.1 - 2.7e-47 161.0 10.1 3.6e-47 160.6 10.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.11 KXT05213.1 - 0.069 13.2 1.0 0.083 12.9 0.2 1.6 2 0 0 2 2 2 0 Neugrin TPR_MLP1_2 PF07926.12 KXT05213.1 - 3.5 7.7 7.2 8.6 6.4 0.5 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Surface_Ag_2 PF01617.17 KXT05214.1 - 0.083 12.3 0.0 8.4 5.7 0.0 2.2 2 0 0 2 2 2 0 Surface antigen SWIB PF02201.18 KXT05215.1 - 6.8e-23 80.3 0.1 2e-22 78.9 0.0 1.9 2 0 0 2 2 2 1 SWIB/MDM2 domain Calici_MSP PF05752.11 KXT05215.1 - 0.025 14.4 0.1 0.044 13.6 0.1 1.4 1 0 0 1 1 1 0 Calicivirus minor structural protein SurA_N_3 PF13624.6 KXT05215.1 - 0.059 13.2 0.5 0.11 12.2 0.5 1.5 1 0 0 1 1 1 0 SurA N-terminal domain OPT PF03169.15 KXT05216.1 - 5.1e-150 501.1 15.7 5.8e-150 500.9 15.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Clr5 PF14420.6 KXT05217.1 - 5e-14 52.2 0.2 3.6e-12 46.3 0.0 3.0 2 0 0 2 2 2 1 Clr5 domain HTH_38 PF13936.6 KXT05217.1 - 0.022 14.5 0.2 3.4 7.5 0.1 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain PAS_9 PF13426.7 KXT05218.1 - 2.5e-07 30.9 0.0 1.3e-06 28.5 0.0 2.3 2 1 1 3 3 3 1 PAS domain DUF5578 PF17741.1 KXT05219.1 - 0.033 13.6 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5578) XFP_N PF09364.10 KXT05220.1 - 3.6e-170 565.6 0.0 5.9e-170 564.9 0.0 1.3 1 0 0 1 1 1 1 XFP N-terminal domain XFP PF03894.15 KXT05220.1 - 1.2e-82 275.9 0.0 3e-82 274.6 0.0 1.6 2 0 0 2 2 2 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.10 KXT05220.1 - 3.4e-81 271.5 0.0 5.3e-81 270.9 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain MFS_1 PF07690.16 KXT05221.1 - 8.5e-21 74.3 22.4 8.5e-21 74.3 22.4 2.9 2 1 1 3 3 3 3 Major Facilitator Superfamily AlphaC_C PF17480.2 KXT05225.1 - 0.074 13.1 0.5 0.11 12.6 0.1 1.5 2 0 0 2 2 2 0 AlphaC C-terminal SKG6 PF08693.10 KXT05226.1 - 1.3e-05 24.5 0.4 2.3e-05 23.7 0.4 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Peptidase_C13 PF01650.18 KXT05228.1 - 7e-39 133.9 0.0 1e-38 133.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C13 PF01650.18 KXT05230.1 - 7e-39 133.9 0.0 1e-38 133.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase C13 family ATP-synt_ab_C PF00306.27 KXT05231.1 - 0.11 12.8 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta chain, C terminal domain DA1-like PF12315.8 KXT05232.1 - 0.37 10.2 0.0 0.37 10.2 0.0 2.2 2 1 0 2 2 2 0 Protein DA1 Aldo_ket_red PF00248.21 KXT05233.1 - 8.1e-62 209.1 0.0 9.6e-62 208.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3223 PF11523.8 KXT05233.1 - 0.18 12.7 0.0 0.4 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3223) LAM_C PF12544.8 KXT05234.1 - 0.00013 22.2 0.0 0.00026 21.1 0.0 1.4 1 0 0 1 1 1 1 Lysine-2,3-aminomutase Fer4_14 PF13394.6 KXT05234.1 - 0.001 19.2 0.0 0.0016 18.5 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Radical_SAM PF04055.21 KXT05234.1 - 0.0084 16.5 0.0 0.021 15.2 0.0 1.9 1 1 0 1 1 1 1 Radical SAM superfamily PPP4R2 PF09184.11 KXT05235.1 - 9.2e-07 28.7 0.0 9.2e-07 28.7 0.0 2.9 3 1 0 3 3 3 1 PPP4R2 DUF4699 PF15770.5 KXT05235.1 - 2.1 8.0 12.9 0.036 13.8 5.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4699) Zn_clus PF00172.18 KXT05236.1 - 1.2e-06 28.5 9.4 2.4e-06 27.6 9.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_4 PF01063.19 KXT05237.1 - 9.9e-27 94.2 0.0 1.5e-26 93.7 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV Iso_dh PF00180.20 KXT05238.1 - 8.2e-73 245.5 0.0 9.6e-73 245.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase TPP_enzyme_C PF02775.21 KXT05240.1 - 3.8e-41 140.4 0.2 7.6e-39 132.9 0.1 3.2 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_N PF02776.18 KXT05240.1 - 1.3e-38 132.3 0.1 1.3e-33 116.0 0.0 2.8 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KXT05240.1 - 1.7e-35 121.7 0.0 4.2e-35 120.5 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Fucose_iso_N1 PF07881.12 KXT05240.1 - 0.0041 17.0 1.6 0.35 10.7 0.0 3.5 4 0 0 4 4 4 1 L-fucose isomerase, first N-terminal domain DnaJ PF00226.31 KXT05241.1 - 2.8e-19 69.0 0.8 5.1e-19 68.1 0.8 1.5 1 0 0 1 1 1 1 DnaJ domain SIP1 PF04938.12 KXT05241.1 - 0.24 11.1 2.6 0.2 11.4 0.5 1.9 2 0 0 2 2 2 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) Adap_comp_sub PF00928.21 KXT05242.1 - 1.3e-60 205.0 0.0 1.6e-60 204.7 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KXT05242.1 - 0.012 15.5 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 Clathrin adaptor complex small chain Amidohydro_2 PF04909.14 KXT05243.1 - 7.4e-48 163.8 0.0 8.5e-48 163.6 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase BTB PF00651.31 KXT05244.1 - 2.2e-06 27.9 0.0 7.1e-06 26.2 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain VAD1-2 PF15310.6 KXT05244.1 - 0.025 14.4 0.7 0.047 13.6 0.7 1.4 1 0 0 1 1 1 0 Vitamin A-deficiency (VAD) rat model signalling Skp1_POZ PF03931.15 KXT05244.1 - 0.2 11.9 0.0 1.2 9.3 0.0 2.1 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain Abhydrolase_1 PF00561.20 KXT05245.1 - 0.0016 18.2 0.0 0.011 15.3 0.0 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXT05245.1 - 0.0021 17.4 0.1 0.0068 15.7 0.1 1.7 1 1 0 2 2 2 1 Serine aminopeptidase, S33 Lipase_3 PF01764.25 KXT05245.1 - 0.022 14.6 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF818 PF05677.12 KXT05245.1 - 0.089 11.7 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) MFS_1 PF07690.16 KXT05247.1 - 2e-05 23.7 5.7 3e-05 23.1 5.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Ribosomal_L18A PF01775.17 KXT05248.1 - 9.6e-55 183.9 0.5 1.2e-54 183.5 0.5 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Ras PF00071.22 KXT05249.1 - 7.1e-49 165.5 0.0 8.9e-49 165.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXT05249.1 - 3.8e-29 101.3 0.1 9.6e-29 100.0 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXT05249.1 - 2.1e-10 40.3 0.0 2.7e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KXT05249.1 - 0.00055 20.0 0.0 0.00097 19.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 KXT05249.1 - 0.00062 20.1 0.1 0.003 17.9 0.1 2.0 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.12 KXT05249.1 - 0.0016 17.8 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Pox_A32 PF04665.12 KXT05249.1 - 0.017 14.6 0.1 0.028 13.9 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein G-alpha PF00503.20 KXT05249.1 - 0.021 14.0 2.4 0.82 8.8 0.1 2.6 2 1 1 3 3 3 0 G-protein alpha subunit AAA_7 PF12775.7 KXT05249.1 - 0.029 13.9 0.1 0.051 13.1 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KXT05249.1 - 0.059 13.1 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KXT05249.1 - 0.093 13.1 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 KXT05249.1 - 0.093 12.6 0.1 8.4 6.3 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase TsaE PF02367.17 KXT05249.1 - 0.093 12.7 0.1 0.21 11.6 0.1 1.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ArgoMid PF16487.5 KXT05249.1 - 0.096 13.0 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Mid domain of argonaute AAA_33 PF13671.6 KXT05249.1 - 0.11 12.6 0.2 0.22 11.7 0.2 1.5 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 KXT05249.1 - 0.17 11.2 0.7 0.24 10.6 0.1 1.6 2 0 0 2 2 2 0 Septin adh_short PF00106.25 KXT05251.1 - 2.2e-35 121.9 0.0 2.7e-35 121.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT05251.1 - 3.2e-30 105.4 0.0 4.5e-30 104.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KXT05251.1 - 0.00014 21.4 0.0 0.0014 18.2 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KXT05251.1 - 0.00021 21.3 0.1 0.00077 19.4 0.1 1.8 1 1 0 1 1 1 1 KR domain Bap31 PF05529.12 KXT05252.1 - 1.8e-47 160.6 7.8 2.2e-47 160.3 7.8 1.1 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 KXT05252.1 - 3.2e-14 52.7 2.9 3.2e-14 52.7 2.9 1.9 2 0 0 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain FlaC_arch PF05377.11 KXT05252.1 - 0.026 14.9 0.5 0.026 14.9 0.5 1.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 KXT05252.1 - 0.06 13.1 10.3 0.31 10.8 1.7 3.8 3 1 1 4 4 4 0 Septum formation initiator Csm1_N PF18504.1 KXT05252.1 - 0.087 13.2 0.4 0.087 13.2 0.4 1.8 2 0 0 2 2 2 0 Csm1 N-terminal domain bZIP_1 PF00170.21 KXT05252.1 - 0.23 11.6 5.2 9.2 6.5 0.1 2.5 2 0 0 2 2 2 0 bZIP transcription factor PKcGMP_CC PF16808.5 KXT05252.1 - 1.1 9.2 6.7 0.23 11.4 2.8 1.8 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Lebercilin PF15619.6 KXT05253.1 - 0.0095 15.6 34.4 0.013 15.2 25.0 2.5 3 0 0 3 3 3 2 Ciliary protein causing Leber congenital amaurosis disease MPS2 PF17060.5 KXT05253.1 - 0.055 12.7 10.7 0.11 11.7 10.7 1.5 1 1 0 1 1 1 0 Monopolar spindle protein 2 GAS PF13851.6 KXT05253.1 - 0.099 12.0 26.8 3.7 6.9 0.1 2.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF1127 PF06568.11 KXT05253.1 - 0.51 10.1 3.2 1.7 8.5 3.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1127) DUF4357 PF14267.6 KXT05253.1 - 0.54 10.2 2.2 1.7 8.7 2.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4357) Phage_GP20 PF06810.11 KXT05253.1 - 0.98 9.2 21.5 0.33 10.8 1.2 3.9 2 1 2 4 4 4 0 Phage minor structural protein GP20 DUF948 PF06103.11 KXT05253.1 - 2.5 8.4 14.9 11 6.3 0.6 3.6 4 0 0 4 4 3 0 Bacterial protein of unknown function (DUF948) LMBR1 PF04791.16 KXT05253.1 - 2.9 6.7 13.4 1.2 8.0 10.7 1.6 2 0 0 2 2 2 0 LMBR1-like membrane protein HAP1_N PF04849.13 KXT05253.1 - 3.2 6.9 29.7 0.3 10.2 0.4 3.3 2 1 0 2 2 2 0 HAP1 N-terminal conserved region DUF4407 PF14362.6 KXT05253.1 - 6.8 5.9 24.7 1.2 8.4 3.5 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) IKKbetaNEMObind PF12179.8 KXT05253.1 - 7.2 6.7 9.3 1.2 9.2 0.8 3.1 2 1 1 3 3 3 0 I-kappa-kinase-beta NEMO binding domain NPV_P10 PF05531.12 KXT05253.1 - 8.1 7.0 12.3 0.37 11.3 0.9 3.6 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein DASH_Dad2 PF08654.10 KXT05253.1 - 8.3 6.9 15.0 10 6.6 8.7 3.2 2 1 1 3 3 3 0 DASH complex subunit Dad2 Aminotran_5 PF00266.19 KXT05255.1 - 3.6e-57 194.0 0.0 5.4e-57 193.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KXT05255.1 - 0.00071 18.2 0.0 0.0027 16.3 0.0 1.9 2 1 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme ORC4_C PF14629.6 KXT05255.1 - 0.1 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 4 C-terminus NmrA PF05368.13 KXT05257.1 - 1.7e-22 80.2 0.0 2.2e-22 79.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXT05257.1 - 2e-08 34.4 0.0 8e-08 32.4 0.0 2.1 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KXT05257.1 - 0.00022 21.5 0.1 0.0027 18.0 0.0 2.1 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 KXT05257.1 - 0.056 13.7 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.20 KXT05257.1 - 0.057 13.5 0.0 0.28 11.2 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NmrA PF05368.13 KXT05258.1 - 6.7e-18 65.1 0.0 9.1e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXT05258.1 - 1.8e-07 31.3 0.0 9.4e-07 28.9 0.0 2.3 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KXT05258.1 - 0.00022 21.5 0.1 0.0027 17.9 0.0 2.1 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KXT05258.1 - 0.043 13.9 0.0 0.21 11.6 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 KXT05258.1 - 0.052 13.8 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain ThiF PF00899.21 KXT05258.1 - 0.15 11.4 0.1 0.45 9.8 0.0 1.7 2 0 0 2 2 2 0 ThiF family Aminotran_5 PF00266.19 KXT05259.1 - 3.6e-57 194.0 0.0 5.4e-57 193.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KXT05259.1 - 0.00071 18.2 0.0 0.0027 16.3 0.0 1.9 2 1 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme ORC4_C PF14629.6 KXT05259.1 - 0.1 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 4 C-terminus Aminotran_5 PF00266.19 KXT05260.1 - 3.6e-57 194.0 0.0 5.4e-57 193.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KXT05260.1 - 0.00071 18.2 0.0 0.0027 16.3 0.0 1.9 2 1 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme ORC4_C PF14629.6 KXT05260.1 - 0.1 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 4 C-terminus TPR_1 PF00515.28 KXT05261.1 - 1.2e-35 119.8 32.2 2.1e-05 24.2 0.1 11.5 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_2 PF07719.17 KXT05261.1 - 1.8e-34 115.1 28.7 0.00052 19.9 0.1 11.6 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_17 PF13431.6 KXT05261.1 - 2e-25 87.3 8.1 0.00011 22.3 0.0 8.7 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_11 PF13414.6 KXT05261.1 - 1.9e-24 85.0 26.2 0.00022 20.8 0.0 8.9 7 2 2 9 9 9 7 TPR repeat TPR_16 PF13432.6 KXT05261.1 - 9.1e-24 83.8 23.7 6.9e-06 26.6 0.6 7.8 7 2 1 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.6 KXT05261.1 - 1.5e-14 54.0 23.1 0.0014 18.9 0.0 8.2 7 3 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 KXT05261.1 - 4.2e-14 51.5 32.2 0.024 14.8 0.1 10.3 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_19 PF14559.6 KXT05261.1 - 2e-12 47.4 20.9 0.00011 22.6 0.8 7.1 6 1 0 6 6 6 4 Tetratricopeptide repeat TPR_9 PF13371.6 KXT05261.1 - 6.7e-12 45.4 14.6 0.0025 17.9 0.3 6.5 6 1 2 8 8 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 KXT05261.1 - 6.6e-10 38.3 19.5 0.052 13.6 0.1 8.8 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_14 PF13428.6 KXT05261.1 - 1.3e-09 38.0 17.3 0.032 15.0 0.3 8.7 4 3 5 9 9 9 2 Tetratricopeptide repeat TPR_10 PF13374.6 KXT05261.1 - 2.9e-06 26.9 24.1 0.03 14.2 0.2 7.7 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KXT05261.1 - 3.5e-05 23.4 4.3 7.1e-05 22.3 0.7 2.6 2 1 0 2 2 2 1 MalT-like TPR region ANAPC3 PF12895.7 KXT05261.1 - 7.2e-05 22.9 16.8 0.15 12.3 0.2 5.8 3 2 4 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 MAS20 PF02064.15 KXT05261.1 - 0.0022 18.1 6.9 0.49 10.5 0.1 4.7 4 1 1 5 5 5 1 MAS20 protein import receptor Sel1 PF08238.12 KXT05261.1 - 0.0044 17.7 3.4 1.7 9.5 0.0 4.2 4 0 0 4 4 2 1 Sel1 repeat SHNi-TPR PF10516.9 KXT05261.1 - 0.0047 16.3 15.0 0.66 9.5 0.1 5.9 6 0 0 6 6 5 2 SHNi-TPR DUF3856 PF12968.7 KXT05261.1 - 0.0059 16.7 4.0 4.9 7.2 0.0 4.5 4 1 0 4 4 4 1 Domain of Unknown Function (DUF3856) MIT PF04212.18 KXT05261.1 - 0.03 14.4 21.1 6.9 6.8 0.4 6.5 7 0 0 7 7 6 0 MIT (microtubule interacting and transport) domain DUF3808 PF10300.9 KXT05261.1 - 0.077 11.7 3.3 3.1 6.4 0.1 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF3808) Alkyl_sulf_dimr PF14863.6 KXT05261.1 - 0.21 12.0 4.5 28 5.2 0.1 4.2 2 2 1 3 3 3 0 Alkyl sulfatase dimerisation IPPT PF01715.17 KXT05261.1 - 0.41 10.4 4.3 1.8 8.3 1.8 3.0 2 1 0 2 2 2 0 IPP transferase TPR_6 PF13174.6 KXT05261.1 - 0.58 10.9 24.5 3.5 8.4 0.0 8.3 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_20 PF14561.6 KXT05261.1 - 5.3 7.4 17.1 6.5 7.2 0.1 6.1 6 1 1 7 7 7 0 Tetratricopeptide repeat Response_reg PF00072.24 KXT05262.1 - 3.7e-26 91.5 0.2 9e-26 90.3 0.2 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 KXT05262.1 - 6e-23 81.5 0.0 1.7e-21 76.8 0.0 2.7 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KXT05262.1 - 4.5e-14 52.2 0.0 1.7e-13 50.4 0.0 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 KXT05262.1 - 0.046 14.1 2.5 0.68 10.4 0.2 3.1 2 0 0 2 2 2 0 HAMP domain Mit_ribos_Mrp51 PF11709.8 KXT05264.1 - 0.094 12.3 1.0 0.1 12.2 1.0 1.0 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit HWE_HK PF07536.14 KXT05265.1 - 0.095 13.4 0.0 0.58 10.9 0.0 2.1 2 0 0 2 2 2 0 HWE histidine kinase Zn_clus PF00172.18 KXT05266.1 - 5.9e-07 29.5 9.8 1.3e-06 28.5 9.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXT05266.1 - 0.00032 19.8 0.1 0.0007 18.7 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_30 PF05430.11 KXT05266.1 - 0.028 14.3 0.4 0.079 12.8 0.1 1.8 2 0 0 2 2 2 0 S-adenosyl-L-methionine-dependent methyltransferase zf-C2H2_2 PF12756.7 KXT05267.1 - 0.00034 20.9 0.7 0.00053 20.3 0.7 1.2 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) NAD_binding_10 PF13460.6 KXT05270.1 - 6e-12 45.8 0.0 1.2e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXT05270.1 - 4.8e-11 42.7 0.1 8.6e-11 41.8 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KXT05270.1 - 0.00027 20.5 0.1 0.00047 19.7 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KXT05270.1 - 0.0014 19.1 0.1 0.0028 18.1 0.1 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KXT05270.1 - 0.0018 18.5 0.1 0.0032 17.7 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 KXT05270.1 - 0.004 17.3 0.2 0.019 15.1 0.2 2.1 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.22 KXT05270.1 - 0.0085 16.9 0.3 0.016 16.0 0.3 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GDP_Man_Dehyd PF16363.5 KXT05270.1 - 0.031 13.7 0.0 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase KR PF08659.10 KXT05270.1 - 0.046 13.6 0.0 0.09 12.7 0.0 1.5 1 0 0 1 1 1 0 KR domain Rossmann-like PF10727.9 KXT05270.1 - 0.055 13.3 0.0 0.097 12.5 0.0 1.4 1 0 0 1 1 1 0 Rossmann-like domain 3Beta_HSD PF01073.19 KXT05270.1 - 0.092 11.7 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Ribonuc_red_lgN PF00317.21 KXT05270.1 - 0.12 12.4 0.0 0.31 11.1 0.0 1.6 1 1 0 1 1 1 0 Ribonucleotide reductase, all-alpha domain K_oxygenase PF13434.6 KXT05270.1 - 0.12 11.5 0.1 0.18 10.9 0.1 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) PglD_N PF17836.1 KXT05270.1 - 0.14 12.9 0.0 15 6.3 0.0 2.4 2 0 0 2 2 2 0 PglD N-terminal domain CX9C PF16860.5 KXT05271.1 - 0.00036 20.5 1.6 0.00046 20.1 1.6 1.1 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, NDUF_B7 PF05676.13 KXT05271.1 - 0.042 13.6 2.6 2.4 8.0 0.7 2.0 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CHCH PF06747.13 KXT05271.1 - 0.31 11.2 3.0 0.64 10.2 2.9 1.7 1 1 1 2 2 2 0 CHCH domain Sec62 PF03839.16 KXT05285.1 - 1.3e-71 240.6 4.0 3.2e-71 239.3 4.0 1.7 1 0 0 1 1 1 1 Translocation protein Sec62 MFS_1 PF07690.16 KXT05285.1 - 3.6e-35 121.5 36.1 1.2e-32 113.2 19.7 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXT05285.1 - 5.7e-35 121.0 19.1 5.7e-35 121.0 19.1 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter MPM1 PF17234.2 KXT05285.1 - 0.062 13.6 0.3 0.062 13.6 0.3 2.2 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 SARAF PF06682.12 KXT05285.1 - 6.1 6.4 8.3 0.32 10.6 0.1 2.7 3 1 1 4 4 4 0 SOCE-associated regulatory factor of calcium homoeostasis PP2C PF00481.21 KXT05286.1 - 1.1e-62 212.0 0.1 3.5e-59 200.5 0.0 3.3 1 1 1 2 2 2 2 Protein phosphatase 2C FAD_binding_4 PF01565.23 KXT05287.1 - 4.2e-18 65.4 3.9 7.3e-18 64.6 2.0 2.4 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KXT05287.1 - 9.5e-10 38.4 0.1 2.6e-09 37.0 0.1 1.8 2 0 0 2 2 2 1 Berberine and berberine like CBS PF00571.28 KXT05288.1 - 6.8e-20 71.3 6.2 1.2e-07 32.1 0.1 3.8 4 0 0 4 4 4 3 CBS domain CBS PF00571.28 KXT05289.1 - 6.8e-20 71.3 6.2 1.2e-07 32.1 0.1 3.8 4 0 0 4 4 4 3 CBS domain Zn_clus PF00172.18 KXT05290.1 - 4.8e-07 29.8 12.0 8.2e-07 29.1 12.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pro-kuma_activ PF09286.11 KXT05292.1 - 8e-42 142.9 0.1 1.3e-41 142.3 0.1 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KXT05292.1 - 2e-06 27.3 1.8 3.2e-06 26.6 1.8 1.4 1 0 0 1 1 1 1 Subtilase family JUPITER PF17054.5 KXT05292.1 - 0.033 13.7 0.1 0.057 12.9 0.1 1.3 1 0 0 1 1 1 0 Microtubule-Associated protein Jupiter 6PF2K PF01591.18 KXT05294.1 - 7.9e-62 208.5 0.0 1.2e-61 207.9 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KXT05294.1 - 6.9e-22 78.1 1.1 5.1e-21 75.3 1.1 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KXT05294.1 - 0.031 14.4 0.0 0.093 12.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain CdvA PF18822.1 KXT05295.1 - 0.092 12.6 1.2 0.2 11.5 1.2 1.4 1 0 0 1 1 1 0 CdvA-like coiled-coil domain CdvA PF18822.1 KXT05296.1 - 0.095 12.5 1.2 0.2 11.5 1.2 1.4 1 0 0 1 1 1 0 CdvA-like coiled-coil domain PQ-loop PF04193.14 KXT05297.1 - 3.2e-35 119.7 8.0 4.3e-17 61.6 3.2 2.3 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.16 KXT05297.1 - 0.0043 17.0 0.3 0.025 14.6 0.2 2.1 2 0 0 2 2 2 1 Sugar efflux transporter for intercellular exchange S6OS1 PF15676.5 KXT05297.1 - 0.34 9.3 0.1 0.44 9.0 0.1 1.1 1 0 0 1 1 1 0 Six6 opposite strand transcript 1 family Nup192 PF11894.8 KXT05298.1 - 3.4e-297 989.2 4.3 4.4e-297 988.8 4.3 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 Nup192 PF11894.8 KXT05299.1 - 3.4e-297 989.2 4.3 4.4e-297 988.8 4.3 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 SDA1 PF05285.12 KXT05301.1 - 1.1e-96 324.3 40.0 1.1e-96 324.3 40.0 2.1 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.12 KXT05301.1 - 6.8e-23 80.7 0.1 2e-22 79.3 0.1 1.9 1 0 0 1 1 1 1 NUC130/3NT domain Abhydrolase_1 PF00561.20 KXT05302.1 - 1e-08 35.2 0.0 1.3e-07 31.5 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXT05302.1 - 0.0048 16.2 0.0 0.0075 15.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXT05302.1 - 0.012 16.2 0.0 0.017 15.7 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KXT05302.1 - 0.016 14.6 0.0 0.039 13.4 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KXT05303.1 - 1e-08 35.2 0.0 1.3e-07 31.5 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXT05303.1 - 0.0048 16.2 0.0 0.0075 15.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXT05303.1 - 0.012 16.2 0.0 0.017 15.7 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KXT05303.1 - 0.016 14.6 0.0 0.039 13.4 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF1664 PF07889.12 KXT05304.1 - 0.00092 19.2 20.2 0.0075 16.3 0.7 4.6 2 2 2 5 5 5 2 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 KXT05304.1 - 0.0017 18.4 30.4 0.19 11.7 0.7 5.0 3 1 1 4 4 4 3 Baculovirus polyhedron envelope protein, PEP, C terminus HTH_46 PF15977.5 KXT05304.1 - 0.0037 17.2 0.0 0.97 9.5 0.0 2.6 2 0 0 2 2 2 1 Winged helix-turn-helix DNA binding DASH_Dad1 PF08649.10 KXT05304.1 - 0.0061 16.7 3.0 0.59 10.4 0.1 4.0 3 1 1 4 4 4 1 DASH complex subunit Dad1 Fib_alpha PF08702.10 KXT05304.1 - 0.054 13.7 0.4 0.054 13.7 0.4 4.1 2 1 3 5 5 5 0 Fibrinogen alpha/beta chain family NETI PF14044.6 KXT05304.1 - 0.069 12.9 1.1 41 4.0 0.0 3.8 4 0 0 4 4 4 0 NETI protein DUF2937 PF11157.8 KXT05304.1 - 0.3 10.8 3.7 4.6 6.9 0.3 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2937) ApoC-I PF04691.12 KXT05304.1 - 0.61 10.1 5.9 3.5 7.6 0.1 4.1 3 1 1 4 4 4 0 Apolipoprotein C-I (ApoC-1) Suv3_N PF18114.1 KXT05304.1 - 0.64 10.1 3.0 9.8 6.3 0.5 3.0 2 1 1 3 3 3 0 Suv3 helical N-terminal domain FlaC_arch PF05377.11 KXT05304.1 - 0.68 10.4 16.2 4.4 7.8 0.4 5.2 5 1 1 6 6 4 0 Flagella accessory protein C (FlaC) DUF2730 PF10805.8 KXT05304.1 - 1.5 9.0 13.2 29 4.8 0.2 5.1 2 2 2 5 5 5 0 Protein of unknown function (DUF2730) DUF349 PF03993.12 KXT05304.1 - 2.1 8.7 11.1 0.41 11.0 3.8 3.4 1 1 2 3 3 3 0 Domain of Unknown Function (DUF349) Acyl-CoA_dh_2 PF08028.11 KXT05304.1 - 2.6 8.3 9.9 0.078 13.2 0.8 2.9 1 1 2 4 4 4 0 Acyl-CoA dehydrogenase, C-terminal domain FUSC PF04632.12 KXT05304.1 - 4.6 5.7 12.1 3 6.3 6.2 2.7 1 1 1 3 3 3 0 Fusaric acid resistance protein family CorA PF01544.18 KXT05304.1 - 5 6.4 15.2 2.1 7.6 0.3 3.1 1 1 2 3 3 3 0 CorA-like Mg2+ transporter protein Prefoldin_2 PF01920.20 KXT05304.1 - 8 6.5 25.0 0.5 10.3 3.7 5.2 3 2 2 6 6 6 0 Prefoldin subunit DUF489 PF04356.12 KXT05304.1 - 9.6 6.2 13.8 27 4.7 0.0 4.4 2 2 3 6 6 6 0 Protein of unknown function (DUF489) MFS_1 PF07690.16 KXT05305.1 - 5.7e-37 127.5 36.1 9.5e-35 120.1 25.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXT05305.1 - 0.00013 20.6 3.7 0.00013 20.6 3.7 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) ESSS PF10183.9 KXT05305.1 - 0.026 14.7 0.1 0.1 12.9 0.1 2.0 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) ADH_zinc_N PF00107.26 KXT05306.1 - 0.0003 20.8 0.1 0.00053 20.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glyco_transf_90 PF05686.12 KXT05307.1 - 8.6e-16 57.8 3.2 1.9e-11 43.5 1.4 3.8 2 1 0 2 2 2 2 Glycosyl transferase family 90 Mannosidase_ig PF17786.1 KXT05308.1 - 2e-20 73.2 0.7 6.7e-20 71.5 0.3 2.1 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KXT05308.1 - 3.6e-10 40.5 0.0 4.9e-09 36.8 0.0 2.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Ras PF00071.22 KXT05309.1 - 8e-62 207.6 0.1 9.3e-62 207.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXT05309.1 - 1.6e-35 121.9 0.2 2.2e-35 121.5 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXT05309.1 - 5.9e-13 48.6 0.0 7e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KXT05309.1 - 3.2e-07 30.4 0.1 4.8e-07 29.9 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXT05309.1 - 0.00018 21.5 0.1 0.016 15.1 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 KXT05309.1 - 0.0017 17.8 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KXT05309.1 - 0.0029 17.2 0.1 0.015 14.8 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KXT05309.1 - 0.0036 17.6 0.1 0.028 14.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KXT05309.1 - 0.0073 16.7 0.1 0.015 15.7 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 KXT05309.1 - 0.022 15.3 0.1 0.038 14.5 0.1 1.4 1 1 0 1 1 1 0 ABC transporter SRPRB PF09439.10 KXT05309.1 - 0.028 13.8 0.0 0.054 12.9 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 KXT05309.1 - 0.036 13.8 0.1 0.067 12.9 0.1 1.6 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 KXT05309.1 - 0.04 13.5 0.0 0.23 11.0 0.0 1.9 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF1128 PF06569.11 KXT05309.1 - 0.049 13.6 0.0 0.096 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1128) TniB PF05621.11 KXT05309.1 - 0.058 12.8 0.0 0.17 11.3 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein AAA_14 PF13173.6 KXT05309.1 - 0.066 13.3 0.1 0.19 11.8 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KXT05309.1 - 0.095 12.2 0.0 0.21 11.1 0.0 1.5 2 0 0 2 2 2 0 P-loop containing dynein motor region MCM PF00493.23 KXT05309.1 - 0.097 11.8 0.0 0.23 10.5 0.0 1.6 1 1 0 1 1 1 0 MCM P-loop domain AAA_21 PF13304.6 KXT05309.1 - 0.099 12.4 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system F-box PF00646.33 KXT05310.1 - 0.00075 19.3 0.3 0.0017 18.2 0.3 1.6 1 0 0 1 1 1 1 F-box domain cwf21 PF08312.12 KXT05311.1 - 2.8e-19 69.0 11.0 5.8e-19 68.0 11.0 1.6 1 0 0 1 1 1 1 cwf21 domain Trans_reg_C PF00486.28 KXT05311.1 - 0.034 14.2 0.8 1.2 9.3 0.1 2.4 1 1 1 2 2 2 0 Transcriptional regulatory protein, C terminal MRP-L28 PF09812.9 KXT05311.1 - 0.32 11.1 5.7 0.067 13.3 2.6 1.4 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L28 GvpG PF05120.12 KXT05311.1 - 2.1 8.4 5.7 1.9 8.5 2.5 2.0 2 0 0 2 2 2 0 Gas vesicle protein G WD40 PF00400.32 KXT05312.1 - 1.3e-38 130.3 16.1 1.5e-05 25.7 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXT05312.1 - 3e-16 59.5 0.0 0.00027 21.2 0.1 4.9 2 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXT05312.1 - 6.3e-05 22.9 0.0 0.035 14.0 0.0 2.8 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KXT05312.1 - 0.00087 18.7 0.0 0.011 15.1 0.0 2.5 1 1 1 3 3 3 1 WD40-like domain COMPASS-Shg1 PF05205.12 KXT05313.1 - 2e-20 73.4 0.0 2e-20 73.4 0.0 2.3 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component shg1 CENP-F_leu_zip PF10473.9 KXT05314.1 - 0.04 13.9 15.8 0.4 10.7 4.1 2.6 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3450 PF11932.8 KXT05314.1 - 0.057 12.7 10.7 0.19 11.0 1.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Prefoldin_2 PF01920.20 KXT05314.1 - 0.065 13.2 16.7 0.61 10.1 4.0 3.4 1 1 1 3 3 3 0 Prefoldin subunit HTH_19 PF12844.7 KXT05314.1 - 0.14 12.2 1.8 8 6.6 0.1 2.9 2 1 1 3 3 3 0 Helix-turn-helix domain APG6_N PF17675.1 KXT05314.1 - 0.24 11.9 19.0 0.16 12.5 3.2 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region KELK PF15796.5 KXT05314.1 - 0.28 11.7 12.2 0.059 13.8 4.6 2.6 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase AAA_13 PF13166.6 KXT05314.1 - 0.29 9.7 14.0 0.37 9.4 14.0 1.0 1 0 0 1 1 1 0 AAA domain Peptidase_C14 PF00656.22 KXT05314.1 - 0.31 11.0 2.3 3.7 7.4 0.3 2.7 2 1 0 2 2 2 0 Caspase domain Phage_GP20 PF06810.11 KXT05314.1 - 0.47 10.2 20.8 0.16 11.8 15.8 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 Cob_adeno_trans PF01923.18 KXT05314.1 - 0.69 10.0 8.5 0.32 11.1 1.2 2.4 1 1 1 2 2 2 0 Cobalamin adenosyltransferase HisKA_3 PF07730.13 KXT05314.1 - 1.1 9.9 8.0 8.1 7.0 0.1 3.9 2 1 2 4 4 4 0 Histidine kinase TPD52 PF04201.15 KXT05314.1 - 1.6 8.3 11.2 0.079 12.6 4.0 2.0 1 1 1 2 2 2 0 Tumour protein D52 family HMMR_N PF15905.5 KXT05314.1 - 4.3 6.7 19.1 5.6 6.3 6.1 2.1 1 1 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal BRE1 PF08647.11 KXT05314.1 - 4.4 7.5 17.2 2.5 8.2 1.3 2.9 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase UPF0242 PF06785.11 KXT05314.1 - 6.2 6.9 15.7 4e+02 1.0 15.8 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Nop14 PF04147.12 KXT05315.1 - 3.5 5.7 12.9 0.26 9.5 7.6 1.6 2 0 0 2 2 2 0 Nop14-like family RXT2_N PF08595.11 KXT05315.1 - 3.8 7.5 8.1 4.4 7.3 2.5 2.5 2 0 0 2 2 2 0 RXT2-like, N-terminal NOA36 PF06524.12 KXT05315.1 - 6.6 6.0 14.4 24 4.1 10.8 2.1 2 0 0 2 2 2 0 NOA36 protein CDC45 PF02724.14 KXT05315.1 - 7.6 4.7 8.3 1.3 7.2 3.8 1.8 2 0 0 2 2 2 0 CDC45-like protein Pro-kuma_activ PF09286.11 KXT05316.1 - 6.6e-20 71.9 0.0 1e-19 71.2 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KXT05316.1 - 0.0014 18.0 0.3 0.0021 17.4 0.3 1.2 1 0 0 1 1 1 1 Subtilase family Pro-kuma_activ PF09286.11 KXT05317.1 - 6.6e-20 71.9 0.0 1e-19 71.2 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KXT05317.1 - 0.0014 18.0 0.3 0.0021 17.4 0.3 1.2 1 0 0 1 1 1 1 Subtilase family Ribosomal_S14 PF00253.21 KXT05318.1 - 1.6e-13 50.2 3.6 1.7e-13 50.1 3.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.6 KXT05318.1 - 0.014 15.3 0.3 0.017 15.1 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) PLDc_2 PF13091.6 KXT05319.1 - 1.1e-15 57.7 0.0 2e-06 27.7 0.0 4.0 3 1 0 3 3 3 2 PLD-like domain PLDc PF00614.22 KXT05319.1 - 4.6e-12 45.6 5.0 2.2e-05 24.4 0.2 3.0 3 0 0 3 3 3 2 Phospholipase D Active site motif Romo1 PF10247.9 KXT05321.1 - 3e-25 88.4 16.7 4.5e-25 87.8 16.7 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.19 KXT05321.1 - 0.049 14.0 4.2 0.061 13.7 4.2 1.2 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Pacs-1 PF10254.9 KXT05322.1 - 0.16 10.9 3.2 0.22 10.4 3.2 1.3 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein Plasmodium_Vir PF05795.11 KXT05322.1 - 0.26 10.7 4.0 0.43 10.0 4.0 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Apt1 PF10351.9 KXT05322.1 - 5.5 5.7 14.5 7.1 5.4 14.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SOG2 PF10428.9 KXT05322.1 - 9.3 5.3 21.7 12 5.0 21.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein GREB1 PF15782.5 KXT05322.1 - 9.7 3.2 7.6 9.9 3.1 7.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer S4 PF01479.25 KXT05323.1 - 2.4e-12 46.4 0.9 2.4e-12 46.4 0.9 2.6 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 KXT05323.1 - 8.9e-06 26.5 0.2 1.8e-05 25.5 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain FHA PF00498.26 KXT05324.1 - 3e-16 59.5 0.0 6.2e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KXT05324.1 - 1.6e-05 25.1 0.0 4.7e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain ERM PF00769.19 KXT05324.1 - 0.0023 17.8 6.0 0.0023 17.8 6.0 2.4 2 0 0 2 2 2 1 Ezrin/radixin/moesin family YhfZ_C PF14503.6 KXT05324.1 - 0.0041 16.7 0.0 0.008 15.8 0.0 1.4 1 0 0 1 1 1 1 YhfZ C-terminal domain CENP-Q PF13094.6 KXT05324.1 - 0.0094 16.2 5.9 0.78 9.9 1.0 2.7 2 0 0 2 2 2 2 CENP-Q, a CENPA-CAD centromere complex subunit Spc29 PF17082.5 KXT05324.1 - 0.026 14.4 2.2 0.078 12.8 2.0 1.9 1 1 0 1 1 1 0 Spindle Pole Component 29 APG6_N PF17675.1 KXT05324.1 - 0.51 10.9 11.5 8.9 6.9 0.1 3.2 3 0 0 3 3 3 0 Apg6 coiled-coil region DUF4407 PF14362.6 KXT05324.1 - 1.5 8.1 10.9 0.11 11.9 5.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DinB_2 PF12867.7 KXT05324.1 - 2.2 8.8 6.1 6.3 7.3 0.0 3.1 2 1 0 3 3 3 0 DinB superfamily Ribosomal_L27A PF00828.19 KXT05325.1 - 3e-31 108.8 1.2 4.8e-31 108.1 1.2 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Prp18 PF02840.15 KXT05327.1 - 5.3e-54 182.2 0.1 5.3e-54 182.2 0.1 2.2 2 1 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 KXT05327.1 - 1.9e-08 33.7 4.1 1.9e-08 33.7 4.1 3.7 4 0 0 4 4 4 1 pre-mRNA processing factor 4 (PRP4) like CDC27 PF09507.10 KXT05327.1 - 0.41 10.0 20.5 0.7 9.2 20.5 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 ApoA-II PF04711.13 KXT05327.1 - 0.42 10.8 3.0 2.7 8.2 0.0 2.6 2 0 0 2 2 2 0 Apolipoprotein A-II (ApoA-II) MATalpha_HMGbox PF04769.12 KXT05327.1 - 0.47 9.7 0.0 0.47 9.7 0.0 1.9 3 0 0 3 3 3 0 Mating-type protein MAT alpha 1 HMG-box Cation_efflux PF01545.21 KXT05328.1 - 1.1e-25 90.6 4.4 1.4e-25 90.2 4.4 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KXT05328.1 - 4e-05 23.7 0.0 8.4e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter MFS_1 PF07690.16 KXT05329.1 - 3.1e-37 128.3 37.5 1.1e-33 116.6 18.2 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXT05329.1 - 1.3e-22 80.3 14.1 5e-22 78.4 14.1 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter DUF4604 PF15377.6 KXT05330.1 - 9.8e-20 71.7 15.8 1.2e-19 71.4 15.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) DUF4604 PF15377.6 KXT05331.1 - 9.8e-20 71.7 15.8 1.2e-19 71.4 15.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Abhydrolase_3 PF07859.13 KXT05332.1 - 2.5e-33 115.7 0.2 3.5e-33 115.2 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXT05332.1 - 1.1e-06 27.9 0.0 1.5e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family AXE1 PF05448.12 KXT05332.1 - 0.00011 21.0 0.0 0.017 13.8 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Say1_Mug180 PF10340.9 KXT05332.1 - 0.0011 17.9 0.0 0.0014 17.6 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase adh_short_C2 PF13561.6 KXT05334.1 - 6.8e-31 107.6 0.0 9.6e-31 107.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXT05334.1 - 3.4e-30 105.0 0.0 4.4e-30 104.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXT05334.1 - 3.4e-07 30.3 0.0 6.2e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXT05334.1 - 0.047 13.2 0.1 0.078 12.4 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.6 KXT05334.1 - 0.13 13.0 0.1 0.23 12.2 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain LDB19 PF13002.7 KXT05337.1 - 1.5e-39 135.7 0.1 4.4e-39 134.2 0.1 1.8 2 0 0 2 2 2 1 Arrestin_N terminal like Arrestin_N PF00339.29 KXT05337.1 - 1.2e-06 28.6 0.0 4.5e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Spo0M PF07070.11 KXT05337.1 - 0.0046 16.5 0.0 0.0079 15.8 0.0 1.3 1 0 0 1 1 1 1 SpoOM protein DIOX_N PF14226.6 KXT05338.1 - 1.2e-26 93.8 0.0 1.9e-26 93.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXT05338.1 - 4e-19 69.0 0.0 6e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CRA_rpt PF07046.11 KXT05338.1 - 0.051 13.7 2.3 0.7 10.1 0.3 2.5 2 0 0 2 2 2 0 Cytoplasmic repetitive antigen (CRA) like repeat Sugar_tr PF00083.24 KXT05339.1 - 1.7e-125 419.4 27.7 2e-125 419.2 27.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXT05339.1 - 4e-28 98.4 52.9 1.2e-26 93.5 24.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXT05339.1 - 0.00037 19.2 25.2 0.0016 17.0 12.3 2.8 2 1 1 3 3 3 2 MFS/sugar transport protein PsbT PF01405.17 KXT05339.1 - 0.25 11.2 2.7 0.96 9.3 2.7 2.0 1 0 0 1 1 1 0 Photosystem II reaction centre T protein XhlA PF10779.9 KXT05339.1 - 4.8 7.5 4.4 3.7 7.8 0.9 2.6 2 0 0 2 2 2 0 Haemolysin XhlA Porin_3 PF01459.22 KXT05340.1 - 9.2e-68 228.6 0.1 1.1e-67 228.4 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin DIOX_N PF14226.6 KXT05342.1 - 3.7e-20 72.8 0.0 5.5e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXT05342.1 - 6.8e-17 61.8 0.0 1.8e-16 60.5 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Flavin_Reduct PF01613.18 KXT05343.1 - 3.3e-17 63.0 0.0 4.9e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain TssC PF17541.2 KXT05343.1 - 0.049 12.5 0.0 0.068 12.0 0.0 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssC, VipB DUF3176 PF11374.8 KXT05344.1 - 2e-33 114.8 0.7 2e-33 114.8 0.7 3.0 2 2 1 3 3 3 1 Protein of unknown function (DUF3176) DUF973 PF06157.11 KXT05344.1 - 8.8 5.3 5.6 4.4 6.3 1.6 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF973) Redoxin PF08534.10 KXT05346.1 - 5.5e-29 100.8 0.0 6.6e-29 100.5 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KXT05346.1 - 8.7e-11 41.8 0.0 1.1e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Dynamin_N PF00350.23 KXT05347.1 - 1.9e-16 60.6 0.2 1.2e-15 57.9 0.0 2.4 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KXT05347.1 - 4.8e-09 36.3 0.0 2e-08 34.3 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KXT05347.1 - 2.4e-06 27.2 0.6 7.3e-05 22.4 0.2 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF2205 PF10224.9 KXT05347.1 - 3.1e-05 23.9 0.7 3.1e-05 23.9 0.7 2.7 3 0 0 3 3 3 1 Short coiled-coil protein Apolipoprotein PF01442.18 KXT05347.1 - 0.0066 16.3 8.5 0.093 12.6 1.6 2.9 2 1 0 2 2 2 2 Apolipoprotein A1/A4/E domain IIGP PF05049.13 KXT05347.1 - 0.034 13.2 0.0 0.08 12.0 0.0 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_18 PF13238.6 KXT05347.1 - 0.093 13.3 0.0 0.73 10.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KXT05347.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE HemX PF04375.14 KXT05347.1 - 0.15 11.3 3.9 4.7 6.4 0.1 2.6 3 0 0 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase UPF0444 PF15475.6 KXT05347.1 - 0.36 11.1 3.4 0.72 10.2 3.4 1.4 1 0 0 1 1 1 0 Transmembrane protein C12orf23, UPF0444 GFO_IDH_MocA PF01408.22 KXT05348.1 - 6.7e-24 85.0 0.0 1.4e-23 83.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KXT05348.1 - 6.7e-12 45.5 0.0 1.3e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 KXT05348.1 - 0.00083 20.0 0.0 0.0016 19.1 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.20 KXT05348.1 - 0.024 14.7 0.0 0.045 13.9 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus CoA_binding PF02629.19 KXT05348.1 - 0.14 12.9 0.0 0.34 11.6 0.0 1.7 1 0 0 1 1 1 0 CoA binding domain UPF0052 PF01933.18 KXT05349.1 - 5.9e-62 209.5 0.0 1.1e-61 208.6 0.0 1.3 1 1 0 1 1 1 1 Uncharacterised protein family UPF0052 Nop52 PF05997.12 KXT05350.1 - 0.087 12.6 2.4 5.5 6.7 0.0 2.7 3 0 0 3 3 3 0 Nucleolar protein,Nop52 Csd3_N PF18059.1 KXT05350.1 - 0.13 12.8 0.0 0.29 11.7 0.0 1.6 1 0 0 1 1 1 0 Csd3 N-terminal D123 PF07065.14 KXT05351.1 - 7.1e-111 370.2 3.5 8.6e-111 370.0 3.5 1.1 1 0 0 1 1 1 1 D123 FAM176 PF14851.6 KXT05351.1 - 1.7 8.3 7.1 2.4 7.8 0.5 2.4 2 0 0 2 2 2 0 FAM176 family RXT2_N PF08595.11 KXT05351.1 - 6.3 6.8 8.6 15 5.6 1.7 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal Kinesin PF00225.23 KXT05352.1 - 4.2e-112 374.4 0.1 6.6e-112 373.7 0.1 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXT05352.1 - 1.6e-26 93.0 0.0 4e-26 91.7 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding ERM PF00769.19 KXT05352.1 - 0.00077 19.3 13.6 0.0021 17.9 13.6 1.7 1 0 0 1 1 1 1 Ezrin/radixin/moesin family IMD PF08397.11 KXT05352.1 - 0.0059 16.0 4.3 0.012 15.0 4.3 1.5 1 0 0 1 1 1 1 IRSp53/MIM homology domain ZapB PF06005.12 KXT05352.1 - 0.019 15.4 0.0 0.019 15.4 0.0 2.9 2 1 1 3 3 2 0 Cell division protein ZapB YabA PF06156.13 KXT05352.1 - 0.041 14.5 8.7 0.16 12.6 0.9 3.5 3 1 1 4 4 3 0 Initiation control protein YabA Vps53_N PF04100.12 KXT05352.1 - 0.052 12.5 3.8 0.094 11.7 3.8 1.3 1 0 0 1 1 1 0 Vps53-like, N-terminal ATG16 PF08614.11 KXT05352.1 - 0.076 13.2 21.5 0.047 13.9 18.0 2.5 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) PAPS_reduct PF01507.19 KXT05352.1 - 0.35 10.9 3.0 6 6.9 2.0 2.4 2 0 0 2 2 2 0 Phosphoadenosine phosphosulfate reductase family Spc7 PF08317.11 KXT05352.1 - 0.49 9.2 11.3 0.91 8.3 11.3 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Cytochrom_B562 PF07361.11 KXT05352.1 - 0.84 10.3 8.0 2.4 8.9 7.1 2.3 2 0 0 2 2 1 0 Cytochrome b562 SKA2 PF16740.5 KXT05352.1 - 0.85 9.4 8.1 1.6 8.6 5.7 2.3 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 DUF87 PF01935.17 KXT05352.1 - 0.96 9.5 7.5 0.76 9.8 0.1 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain UPF0242 PF06785.11 KXT05352.1 - 1.3 9.1 6.5 3 7.9 6.5 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TMF_DNA_bd PF12329.8 KXT05352.1 - 2.3 8.3 8.3 1.9 8.5 0.2 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TBCC_N PF16752.5 KXT05352.1 - 2.5 8.6 10.4 9.2 6.7 10.4 2.0 1 0 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain DUF1640 PF07798.11 KXT05352.1 - 7.7 6.5 15.0 1.8 8.6 0.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1640) Polysacc_deac_1 PF01522.21 KXT05354.1 - 6.2e-10 39.0 0.0 1.2e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Peptidase_S10 PF00450.22 KXT05355.1 - 2e-69 235.0 3.1 4.4e-68 230.6 3.1 2.5 1 1 0 1 1 1 1 Serine carboxypeptidase EF-hand_4 PF12763.7 KXT05356.1 - 9.5e-07 28.7 0.0 1.9e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand DUF2570 PF10828.8 KXT05356.1 - 0.054 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Fis1_TPR_C PF14853.6 KXT05356.1 - 0.37 10.9 0.8 0.78 9.9 0.8 1.5 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat Apc13p PF05839.11 KXT05357.1 - 8.9e-31 105.9 0.9 1e-30 105.7 0.9 1.0 1 0 0 1 1 1 1 Apc13p protein COX4 PF02936.14 KXT05358.1 - 1.2e-44 151.7 0.1 1.4e-44 151.4 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF3106 PF11304.8 KXT05358.1 - 0.024 15.1 1.9 0.024 15.1 1.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) Arf PF00025.21 KXT05359.1 - 3.7e-66 221.9 1.3 4.1e-66 221.7 1.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KXT05359.1 - 6.4e-13 49.0 0.2 8.6e-13 48.6 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KXT05359.1 - 1.4e-11 44.2 1.4 3.2e-06 26.6 0.2 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KXT05359.1 - 1.4e-11 44.2 0.0 1.7e-11 44.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KXT05359.1 - 2.7e-08 33.4 0.0 3.2e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KXT05359.1 - 6.3e-08 32.7 0.1 1.6e-07 31.4 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 KXT05359.1 - 4.1e-07 29.6 0.0 5e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KXT05359.1 - 0.00031 20.3 0.0 0.014 14.9 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KXT05359.1 - 0.041 13.4 0.4 0.095 12.2 0.4 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B NTPase_1 PF03266.15 KXT05359.1 - 0.078 12.9 0.0 0.099 12.5 0.0 1.3 1 0 0 1 1 1 0 NTPase CdhD PF03599.16 KXT05359.1 - 0.13 11.0 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit 6PF2K PF01591.18 KXT05359.1 - 0.14 11.4 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase HCV_NS1 PF01560.17 KXT05359.1 - 0.16 10.6 0.0 0.21 10.2 0.0 1.2 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein E2/NS1 Arf PF00025.21 KXT05360.1 - 3.7e-66 221.9 1.3 4.1e-66 221.7 1.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KXT05360.1 - 6.4e-13 49.0 0.2 8.6e-13 48.6 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KXT05360.1 - 1.4e-11 44.2 1.4 3.2e-06 26.6 0.2 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KXT05360.1 - 1.4e-11 44.2 0.0 1.7e-11 44.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KXT05360.1 - 2.7e-08 33.4 0.0 3.2e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KXT05360.1 - 6.3e-08 32.7 0.1 1.6e-07 31.4 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 KXT05360.1 - 4.1e-07 29.6 0.0 5e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KXT05360.1 - 0.00031 20.3 0.0 0.014 14.9 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KXT05360.1 - 0.041 13.4 0.4 0.095 12.2 0.4 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B NTPase_1 PF03266.15 KXT05360.1 - 0.078 12.9 0.0 0.099 12.5 0.0 1.3 1 0 0 1 1 1 0 NTPase CdhD PF03599.16 KXT05360.1 - 0.13 11.0 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit 6PF2K PF01591.18 KXT05360.1 - 0.14 11.4 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase HCV_NS1 PF01560.17 KXT05360.1 - 0.16 10.6 0.0 0.21 10.2 0.0 1.2 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein E2/NS1 Arf PF00025.21 KXT05361.1 - 3.7e-66 221.9 1.3 4.1e-66 221.7 1.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KXT05361.1 - 6.4e-13 49.0 0.2 8.6e-13 48.6 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KXT05361.1 - 1.4e-11 44.2 1.4 3.2e-06 26.6 0.2 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KXT05361.1 - 1.4e-11 44.2 0.0 1.7e-11 44.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KXT05361.1 - 2.7e-08 33.4 0.0 3.2e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KXT05361.1 - 6.3e-08 32.7 0.1 1.6e-07 31.4 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 KXT05361.1 - 4.1e-07 29.6 0.0 5e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KXT05361.1 - 0.00031 20.3 0.0 0.014 14.9 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KXT05361.1 - 0.041 13.4 0.4 0.095 12.2 0.4 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B NTPase_1 PF03266.15 KXT05361.1 - 0.078 12.9 0.0 0.099 12.5 0.0 1.3 1 0 0 1 1 1 0 NTPase CdhD PF03599.16 KXT05361.1 - 0.13 11.0 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit 6PF2K PF01591.18 KXT05361.1 - 0.14 11.4 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase HCV_NS1 PF01560.17 KXT05361.1 - 0.16 10.6 0.0 0.21 10.2 0.0 1.2 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein E2/NS1 ERAP1_C PF11838.8 KXT05362.1 - 3.1e-86 289.8 0.1 7.6e-86 288.5 0.1 1.7 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 KXT05362.1 - 1.1e-82 276.9 5.2 2.3e-82 275.8 5.2 1.6 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KXT05362.1 - 5e-45 154.0 0.2 1e-44 153.0 0.2 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain MATalpha_HMGbox PF04769.12 KXT05362.1 - 0.024 14.0 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box Baculo_PEP_C PF04513.12 KXT05363.1 - 1.1 9.3 7.6 22 5.1 7.6 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF883 PF05957.13 KXT05363.1 - 5.4 7.7 11.7 0.7 10.5 5.3 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Macoilin PF09726.9 KXT05363.1 - 5.4 5.4 9.8 6.9 5.1 9.8 1.1 1 0 0 1 1 1 0 Macoilin family MFS_1 PF07690.16 KXT05364.1 - 1e-48 166.1 41.8 1.8e-47 162.0 41.6 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXT05364.1 - 6.7e-18 64.4 11.9 6.7e-18 64.4 11.9 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF1430 PF07242.11 KXT05364.1 - 0.098 12.9 2.0 0.2 11.9 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) Cyclin PF08613.11 KXT05365.1 - 6.6e-13 49.3 0.1 2.2e-12 47.6 0.0 1.9 2 0 0 2 2 2 1 Cyclin Peptidase_M78 PF06114.13 KXT05365.1 - 0.018 15.0 0.3 0.031 14.2 0.3 1.3 1 0 0 1 1 1 0 IrrE N-terminal-like domain Cyclin_N PF00134.23 KXT05365.1 - 0.036 13.8 0.0 0.058 13.1 0.0 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain HAD PF12710.7 KXT05366.1 - 3.2e-25 89.6 0.0 4.7e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXT05366.1 - 1.1e-17 65.0 0.0 1.7e-17 64.4 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KXT05366.1 - 1.6e-11 44.5 0.1 1.9e-10 40.9 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KXT05366.1 - 1.6e-05 25.0 0.0 7.4e-05 22.9 0.0 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KXT05366.1 - 0.00035 20.1 0.0 0.09 12.2 0.0 2.4 2 0 0 2 2 2 2 Putative Phosphatase DUF705 PF05152.12 KXT05366.1 - 0.068 12.6 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF705) S6PP PF05116.13 KXT05366.1 - 0.15 11.6 0.0 1.7 8.1 0.0 2.1 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase FMN_dh PF01070.18 KXT05367.1 - 1.1e-106 356.8 0.0 1.3e-106 356.6 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KXT05367.1 - 1.5e-18 66.7 0.0 3.2e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KXT05367.1 - 5.6e-07 29.0 0.2 1.3e-06 27.8 0.1 1.6 2 0 0 2 2 2 1 Conserved region in glutamate synthase IMPDH PF00478.25 KXT05367.1 - 9.2e-06 24.9 0.7 6.5e-05 22.1 0.0 2.3 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain Tugs PF17840.1 KXT05367.1 - 0.025 14.7 0.3 5.2 7.3 0.0 2.5 2 0 0 2 2 2 0 Tethering Ubl4a to BAGS domain DHO_dh PF01180.21 KXT05367.1 - 0.065 12.4 0.0 0.097 11.9 0.0 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase NMO PF03060.15 KXT05367.1 - 0.1 11.9 0.3 0.17 11.2 0.3 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase Ribul_P_3_epim PF00834.19 KXT05367.1 - 0.13 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family ATP11 PF06644.11 KXT05367.1 - 0.15 11.9 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 ATP11 protein AAA_lid_7 PF17867.1 KXT05368.1 - 0.047 13.9 0.1 1.8 8.8 0.1 2.1 1 1 1 2 2 2 0 Midasin AAA lid domain Geminin PF07412.12 KXT05368.1 - 0.071 12.8 0.0 0.082 12.6 0.0 1.1 1 0 0 1 1 1 0 Geminin Secretin_N_2 PF07655.13 KXT05368.1 - 1.1 9.9 13.0 4.8 7.8 13.0 1.9 1 1 0 1 1 1 0 Secretin N-terminal domain Methyltransf_23 PF13489.6 KXT05369.1 - 2.2e-11 43.9 0.0 4.2e-11 42.9 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXT05369.1 - 0.00022 21.8 0.0 0.00053 20.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXT05369.1 - 0.00047 20.8 0.0 0.0019 18.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Tho2 PF11262.8 KXT05369.1 - 0.082 12.1 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Methyltransf_12 PF08242.12 KXT05369.1 - 0.19 12.5 0.0 0.64 10.8 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Sirohm_synth_C PF14823.6 KXT05370.1 - 8.3e-31 105.4 0.3 1.5e-30 104.6 0.3 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal NAD_binding_7 PF13241.6 KXT05370.1 - 1.2e-30 106.0 0.0 2.3e-30 105.1 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.6 KXT05370.1 - 2.4e-14 52.5 0.3 2.4e-14 52.5 0.3 1.8 2 0 0 2 2 2 1 Sirohaem biosynthesis protein central Pyr_redox_3 PF13738.6 KXT05370.1 - 0.0021 17.4 0.0 0.0029 16.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KXT05370.1 - 0.0041 17.2 0.0 0.0063 16.6 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase LSDAT_prok PF18171.1 KXT05370.1 - 0.067 12.4 0.0 0.096 11.9 0.0 1.2 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote Ssl1 PF04056.14 KXT05371.1 - 3.6e-70 235.7 0.0 4.7e-70 235.3 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 KXT05371.1 - 8.7e-20 70.7 11.0 8.7e-20 70.7 11.0 2.9 2 2 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.6 KXT05371.1 - 8.3e-14 52.1 0.0 1.6e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KXT05371.1 - 5e-05 23.6 0.0 8.7e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 von Willebrand factor type A domain Tfb4 PF03850.14 KXT05371.1 - 0.039 13.4 7.5 0.14 11.6 7.5 2.0 1 1 0 1 1 1 0 Transcription factor Tfb4 zf_CCCH_4 PF18345.1 KXT05372.1 - 2.6e-14 52.7 24.1 6e-05 23.0 3.9 4.0 3 0 0 3 3 3 3 Zinc finger domain zf-CCCH PF00642.24 KXT05372.1 - 2e-12 46.7 16.1 3.2e-05 23.7 1.9 3.8 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) IBR PF01485.21 KXT05372.1 - 4.4e-11 42.8 29.7 7.9e-08 32.4 5.3 3.9 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain Torus PF16131.5 KXT05372.1 - 1.1e-10 42.2 9.8 0.00089 19.9 0.3 3.8 1 1 2 3 3 3 3 Torus domain zf-CCCH_3 PF15663.5 KXT05372.1 - 7.9e-09 35.7 7.2 0.00018 21.7 4.3 3.3 2 1 0 2 2 2 2 Zinc-finger containing family zf-CCCH_4 PF18044.1 KXT05372.1 - 2.2e-07 30.5 26.5 4.6e-05 23.1 1.9 4.0 4 0 0 4 4 3 3 CCCH-type zinc finger zf-C3HC4_4 PF15227.6 KXT05372.1 - 1.5e-06 28.2 5.6 1.5e-06 28.2 5.6 3.6 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 KXT05372.1 - 5.6e-05 22.9 4.1 5.6e-05 22.9 4.1 4.6 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXT05372.1 - 0.00028 20.8 5.4 0.00028 20.8 5.4 3.2 3 0 0 3 3 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KXT05372.1 - 0.00039 20.2 5.9 0.00039 20.2 5.9 3.8 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXT05372.1 - 0.0005 19.9 6.1 0.0005 19.9 6.1 3.7 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXT05372.1 - 0.00077 19.8 6.3 0.00077 19.8 6.3 4.1 3 0 0 3 3 3 1 Ring finger domain zf-CCCH_2 PF14608.6 KXT05372.1 - 0.011 16.2 28.9 0.031 14.7 1.2 4.3 4 0 0 4 4 3 0 RNA-binding, Nab2-type zinc finger zf-RING_5 PF14634.6 KXT05372.1 - 0.012 15.5 5.8 0.012 15.5 5.8 4.0 2 1 0 2 2 1 0 zinc-RING finger domain zf-UDP PF14569.6 KXT05372.1 - 0.069 13.3 8.9 0.29 11.3 8.9 2.0 1 1 0 1 1 1 0 Zinc-binding RING-finger CorA PF01544.18 KXT05374.1 - 1.1e-15 57.8 0.2 2.3e-15 56.7 0.2 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF4045 PF13254.6 KXT05378.1 - 3.7e-88 297.0 34.4 3.7e-88 297.0 34.4 6.3 2 2 4 6 6 6 1 Domain of unknown function (DUF4045) Gelsolin PF00626.22 KXT05378.1 - 5.4e-09 35.8 0.0 0.04 13.8 0.0 3.6 3 0 0 3 3 3 3 Gelsolin repeat PI3_PI4_kinase PF00454.27 KXT05379.1 - 5.1e-56 190.3 0.0 1.2e-55 189.1 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 KXT05379.1 - 3.5e-38 131.1 0.2 3.5e-38 131.1 0.2 3.2 3 0 0 3 3 3 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 KXT05379.1 - 7.8e-10 38.4 0.1 1.7e-09 37.4 0.1 1.6 1 0 0 1 1 1 1 FATC domain FAT PF02259.23 KXT05379.1 - 3.6e-05 23.1 4.5 9.8e-05 21.7 4.5 1.7 1 0 0 1 1 1 1 FAT domain FIVAR PF07554.13 KXT05379.1 - 2.4 9.0 6.8 23 5.8 1.2 2.9 2 0 0 2 2 2 0 FIVAR domain DUF829 PF05705.14 KXT05380.1 - 2.1e-13 50.8 0.0 2.5e-13 50.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) MFS_1 PF07690.16 KXT05381.1 - 7.3e-37 127.1 30.8 7.3e-37 127.1 30.8 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXT05381.1 - 3.2e-14 52.7 4.2 3.2e-14 52.7 4.2 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter TMEM169 PF15052.6 KXT05381.1 - 0.31 11.2 6.3 0.16 12.1 1.7 2.5 2 0 0 2 2 2 0 TMEM169 protein family Pol_alpha_B_N PF08418.10 KXT05382.1 - 6e-78 262.2 0.1 7.9e-78 261.8 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 KXT05382.1 - 7.5e-35 120.2 0.0 1.2e-34 119.6 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B ETF PF01012.21 KXT05384.1 - 6e-42 143.6 0.3 1.2e-41 142.6 0.3 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 KXT05384.1 - 2.1e-33 114.2 0.1 4.2e-33 113.2 0.1 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Pkinase PF00069.25 KXT05385.1 - 5.2e-66 222.7 0.0 6.7e-66 222.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT05385.1 - 1.2e-31 110.0 0.0 1.5e-31 109.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KXT05385.1 - 8.2e-06 25.0 0.1 1.1e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KXT05385.1 - 0.00014 21.3 0.1 0.00047 19.6 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXT05385.1 - 0.00063 19.7 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KXT05385.1 - 0.00075 18.9 0.0 0.051 12.9 0.0 2.3 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 KXT05385.1 - 0.01 15.5 0.2 0.022 14.4 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 KXT05385.1 - 0.022 14.4 0.0 0.043 13.4 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Get5_C PF18514.1 KXT05385.1 - 0.12 12.1 0.1 0.23 11.2 0.1 1.5 1 0 0 1 1 1 0 Get5 C-terminal domain Myb_DNA-bind_7 PF15963.5 KXT05385.1 - 0.43 10.5 1.3 0.7 9.8 0.2 1.9 2 0 0 2 2 2 0 Myb DNA-binding like Ribosomal_S8 PF00410.19 KXT05386.1 - 4.1e-22 78.5 0.1 5.2e-22 78.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 PDEase_II PF02112.15 KXT05387.1 - 2.5e-48 164.9 0.0 6.1e-21 74.9 0.0 3.4 4 0 0 4 4 4 3 cAMP phosphodiesterases class-II Avl9 PF09794.9 KXT05388.1 - 4.2e-132 440.4 0.0 5.3e-132 440.1 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.9 KXT05388.1 - 3.3e-11 43.3 0.2 5.2e-10 39.4 0.1 2.4 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.10 KXT05388.1 - 1.6e-09 37.7 0.2 0.00037 20.4 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis DENN PF02141.21 KXT05388.1 - 0.006 16.6 0.8 0.015 15.3 0.1 2.0 2 0 0 2 2 2 1 DENN (AEX-3) domain Ribosomal_S4Pg PF11993.8 KXT05389.1 - 0.049 13.7 2.9 0.11 12.6 2.9 1.5 1 0 0 1 1 1 0 Ribosomal S4P (gammaproteobacterial) TMEM252 PF15664.5 KXT05389.1 - 0.28 10.9 2.5 6.5 6.5 0.0 2.6 2 0 0 2 2 2 0 Transmembrane protein 252 family HSP20 PF00011.21 KXT05390.1 - 1.9e-12 47.2 0.0 2.7e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KXT05390.1 - 0.0072 15.9 0.0 0.12 11.9 0.0 2.1 2 0 0 2 2 2 1 HSP20-like domain found in ArsA PEPCK_ATP PF01293.20 KXT05390.1 - 0.24 10.0 0.0 0.32 9.6 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase CHCH PF06747.13 KXT05391.1 - 1.1e-07 31.8 4.5 1.1e-07 31.8 4.5 2.4 2 0 0 2 2 2 1 CHCH domain CX9C PF16860.5 KXT05391.1 - 0.00031 20.7 2.0 0.00031 20.7 2.0 2.6 3 0 0 3 3 3 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 KXT05391.1 - 2.8 8.0 10.4 1.6 8.8 2.2 2.7 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like UCR_hinge PF02320.16 KXT05391.1 - 9.4 6.5 10.1 3.2 8.0 5.4 2.8 2 1 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein Med26 PF08711.11 KXT05392.1 - 1.3e-06 28.3 0.6 4.3e-06 26.6 0.0 2.2 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Thy1 PF02511.15 KXT05392.1 - 0.056 13.3 0.3 0.1 12.4 0.3 1.4 1 0 0 1 1 1 0 Thymidylate synthase complementing protein Amidohydro_2 PF04909.14 KXT05393.1 - 1.8e-29 103.5 0.2 7.5e-24 85.0 0.2 2.1 2 0 0 2 2 2 2 Amidohydrolase TatD_DNase PF01026.21 KXT05393.1 - 0.12 11.7 0.0 9 5.6 0.0 2.2 2 0 0 2 2 2 0 TatD related DNase AAA_2 PF07724.14 KXT05394.1 - 9.5e-40 136.5 0.0 4.4e-39 134.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 KXT05394.1 - 6.5e-15 55.7 0.0 1.4e-14 54.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KXT05394.1 - 8.4e-11 41.8 0.0 2.2e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KXT05394.1 - 1.8e-07 31.2 0.0 4.6e-07 29.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KXT05394.1 - 0.00049 19.5 0.5 0.026 13.9 0.1 2.6 2 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 KXT05394.1 - 0.0015 19.0 0.8 0.0068 16.8 0.1 2.5 2 1 0 2 2 2 1 AAA ATPase domain Sigma54_activat PF00158.26 KXT05394.1 - 0.0023 17.7 0.0 0.097 12.4 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain MCM PF00493.23 KXT05394.1 - 0.0026 16.9 0.0 0.0051 15.9 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain AAA_22 PF13401.6 KXT05394.1 - 0.0033 17.7 0.2 0.053 13.8 0.2 2.6 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KXT05394.1 - 0.0044 16.8 0.0 0.0092 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KXT05394.1 - 0.011 15.5 0.1 0.047 13.4 0.0 2.0 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 KXT05394.1 - 0.012 15.3 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 KXT05394.1 - 0.031 13.8 0.0 0.069 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_3 PF07726.11 KXT05394.1 - 0.039 13.8 0.1 0.17 11.8 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KXT05394.1 - 0.078 13.4 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 KXT05394.1 - 0.095 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain DLIC PF05783.11 KXT05394.1 - 0.12 11.1 0.2 0.62 8.8 0.0 2.0 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) ABC_tran PF00005.27 KXT05394.1 - 0.15 12.6 0.0 0.4 11.2 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 KXT05394.1 - 0.68 10.5 0.0 0.68 10.5 0.0 2.5 3 0 0 3 3 2 0 AAA domain adh_short_C2 PF13561.6 KXT05395.1 - 1e-49 169.3 0.3 1.4e-49 168.8 0.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXT05395.1 - 2.8e-45 154.2 0.4 6.5e-45 153.0 0.2 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KXT05395.1 - 9.3e-13 48.5 0.3 1.9e-12 47.4 0.3 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXT05395.1 - 0.003 17.1 0.0 0.017 14.6 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 KXT05395.1 - 0.061 13.3 0.2 0.15 12.0 0.2 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase GCV_T PF01571.21 KXT05396.1 - 0.00069 19.1 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DnaJ PF00226.31 KXT05397.1 - 2.1e-22 79.0 0.6 1e-21 76.8 0.5 2.2 2 0 0 2 2 2 1 DnaJ domain RRM_1 PF00076.22 KXT05397.1 - 0.0084 15.9 0.1 0.039 13.8 0.1 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CRAL_TRIO PF00650.20 KXT05398.1 - 4.2e-35 120.8 0.0 5.7e-35 120.4 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KXT05398.1 - 2.9e-15 56.2 0.0 5.4e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain F-box PF00646.33 KXT05399.1 - 0.003 17.4 0.1 0.007 16.2 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXT05399.1 - 0.079 12.9 0.3 0.15 12.0 0.3 1.5 1 0 0 1 1 1 0 F-box-like Abhydrolase_6 PF12697.7 KXT05400.1 - 2.1e-07 31.8 2.1 4.1e-07 30.8 2.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 KXT05400.1 - 2.7e-05 23.8 0.0 4.6e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KXT05400.1 - 0.0016 18.2 0.0 0.0028 17.4 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Chlorophyllase2 PF12740.7 KXT05400.1 - 0.0034 16.3 0.0 0.0058 15.6 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KXT05400.1 - 0.0042 16.4 0.0 0.01 15.1 0.0 1.6 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KXT05400.1 - 0.0097 15.8 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 KXT05400.1 - 0.058 13.5 1.3 2.7 8.1 0.0 2.8 3 0 0 3 3 3 0 Thioesterase domain DUF915 PF06028.11 KXT05400.1 - 0.14 11.5 0.0 13 5.0 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DUF533 PF04391.12 KXT05400.1 - 0.36 10.4 1.9 0.43 10.1 0.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF533) Lipase_3 PF01764.25 KXT05400.1 - 0.38 10.6 0.0 0.38 10.6 0.0 1.8 2 0 0 2 2 2 0 Lipase (class 3) Acetyltransf_4 PF13420.7 KXT05401.1 - 0.077 13.1 0.1 0.31 11.2 0.1 2.0 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain Cupin_2 PF07883.11 KXT05402.1 - 0.00044 19.9 0.1 0.00092 18.9 0.1 1.6 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KXT05402.1 - 0.024 14.6 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 AraC-like ligand binding domain PBP_sp32 PF07222.12 KXT05403.1 - 4 6.8 11.0 6.7 6.1 11.0 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Peptidase_C12 PF01088.21 KXT05404.1 - 3e-65 219.9 0.0 4.2e-65 219.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KXT05404.1 - 8.4e-12 44.8 0.1 1.9e-11 43.7 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases ADH_zinc_N PF00107.26 KXT05406.1 - 9.7e-20 70.9 0.2 1.7e-19 70.1 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXT05406.1 - 1.6e-06 29.2 0.1 3.8e-06 28.0 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXT05406.1 - 0.0018 18.1 0.0 0.003 17.4 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III_C PF08541.10 KXT05406.1 - 0.1 12.8 0.2 0.21 11.8 0.2 1.5 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Fungal_trans_2 PF11951.8 KXT05407.1 - 6e-16 58.2 4.4 1.3e-05 24.2 0.2 3.1 3 0 0 3 3 3 3 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT05407.1 - 8.8e-09 35.3 5.7 1.5e-08 34.6 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Bac_luciferase PF00296.20 KXT05408.1 - 1.9e-62 211.5 0.6 2.4e-62 211.1 0.6 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase MOSC PF03473.17 KXT05408.1 - 0.13 12.3 0.0 0.29 11.2 0.0 1.6 2 0 0 2 2 2 0 MOSC domain SnoaL_2 PF12680.7 KXT05409.1 - 0.016 15.9 0.0 0.12 13.1 0.0 2.1 1 1 1 2 2 2 0 SnoaL-like domain BOF PF04076.13 KXT05409.1 - 0.05 13.7 0.1 0.12 12.5 0.0 1.6 2 0 0 2 2 2 0 Bacterial OB fold (BOF) protein COesterase PF00135.28 KXT05410.1 - 2.5e-91 307.1 2.2 1.7e-90 304.4 2.2 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXT05410.1 - 0.00033 20.6 0.0 0.00066 19.6 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXT05410.1 - 0.099 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family D_CNTX PF17492.2 KXT05410.1 - 0.27 11.4 6.9 8.9 6.6 2.4 2.5 2 0 0 2 2 2 0 Delta Ctenitoxins CBM_19 PF03427.13 KXT05410.1 - 9 6.4 32.1 0.11 12.5 3.1 4.7 4 0 0 4 4 4 0 Carbohydrate binding domain (family 19) AcetylCoA_hydro PF02550.15 KXT05411.1 - 2e-51 174.8 0.0 3.1e-51 174.2 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 KXT05411.1 - 5e-42 143.4 0.0 9.3e-42 142.6 0.0 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Peptidase_S55 PF05580.12 KXT05411.1 - 0.045 13.7 0.1 0.073 13.0 0.1 1.2 1 0 0 1 1 1 0 SpoIVB peptidase S55 Complex1_LYR PF05347.15 KXT05412.1 - 1.4e-20 73.0 5.5 1.9e-20 72.7 5.5 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KXT05412.1 - 2.9e-07 31.2 1.7 3.1e-07 31.1 1.7 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 KXT05412.1 - 0.0031 18.1 2.3 0.0054 17.3 2.3 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Requiem_N PF14051.6 KXT05412.1 - 0.0057 16.8 1.9 0.0092 16.2 1.9 1.3 1 0 0 1 1 1 1 N-terminal domain of DPF2/REQ. VitD-bind_III PF09164.10 KXT05412.1 - 0.15 12.0 0.3 0.23 11.5 0.3 1.2 1 0 0 1 1 1 0 Vitamin D binding protein, domain III Complex1_LYR PF05347.15 KXT05413.1 - 1.4e-20 73.0 5.5 1.9e-20 72.7 5.5 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KXT05413.1 - 2.9e-07 31.2 1.7 3.1e-07 31.1 1.7 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 KXT05413.1 - 0.0031 18.1 2.3 0.0054 17.3 2.3 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Requiem_N PF14051.6 KXT05413.1 - 0.0057 16.8 1.9 0.0092 16.2 1.9 1.3 1 0 0 1 1 1 1 N-terminal domain of DPF2/REQ. VitD-bind_III PF09164.10 KXT05413.1 - 0.15 12.0 0.3 0.23 11.5 0.3 1.2 1 0 0 1 1 1 0 Vitamin D binding protein, domain III Cupin_2 PF07883.11 KXT05414.1 - 1.8e-13 50.0 0.1 3.2e-13 49.2 0.1 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KXT05414.1 - 1.4e-07 31.3 0.0 1.7e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Cupin CENP-C_C PF11699.8 KXT05414.1 - 0.00014 22.0 0.0 0.00045 20.4 0.0 1.8 1 1 0 1 1 1 1 Mif2/CENP-C like Peptidase_S51 PF03575.17 KXT05415.1 - 3.2e-19 69.4 0.0 4e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family S51 DUF4202 PF13875.6 KXT05416.1 - 5.1e-75 251.5 0.5 5.7e-75 251.3 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) TCTP PF00838.17 KXT05417.1 - 3.3e-72 242.3 2.5 3.6e-72 242.1 2.5 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Sec63 PF02889.16 KXT05418.1 - 7.5e-16 58.1 0.0 1.3e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.31 KXT05418.1 - 9.1e-14 51.3 0.1 2.6e-13 49.9 0.1 1.9 1 0 0 1 1 1 1 DnaJ domain Astacin PF01400.24 KXT05419.1 - 0.0074 15.9 0.1 0.013 15.2 0.1 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Ins_P5_2-kin PF06090.12 KXT05419.1 - 0.096 12.1 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Inositol-pentakisphosphate 2-kinase Tom5 PF10642.9 KXT05420.1 - 1e-20 73.4 1.5 1.1e-20 73.3 1.5 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase HKR_ArcB_TM PF18415.1 KXT05420.1 - 0.095 13.5 0.0 0.098 13.5 0.0 1.1 1 0 0 1 1 1 0 Histidine kinase receptor ArcB trans-membrane domain Nup54 PF13874.6 KXT05421.1 - 1.5e-41 141.8 1.3 1.5e-41 141.8 1.3 2.4 3 1 0 3 3 3 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.6 KXT05421.1 - 4.9e-17 62.6 138.1 9e-10 39.3 36.5 3.0 1 1 2 3 3 3 3 Nucleoporin FG repeat region Nup54_57_C PF18570.1 KXT05421.1 - 1e-12 47.4 4.0 1e-12 47.4 4.0 2.1 2 0 0 2 2 2 1 NUP57/Nup54 C-terminal domain TBCA PF02970.16 KXT05421.1 - 7.5 7.0 9.1 2.2 8.6 0.8 3.0 3 1 0 3 3 3 0 Tubulin binding cofactor A G-alpha PF00503.20 KXT05422.1 - 6.4e-117 390.7 0.3 7.4e-117 390.5 0.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KXT05422.1 - 1.3e-15 57.3 1.0 1.1e-10 41.3 0.2 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KXT05422.1 - 9.6e-05 21.8 1.7 0.017 14.5 1.7 2.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KXT05422.1 - 0.0027 17.9 1.3 1.1 9.5 0.0 2.9 2 1 1 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KXT05422.1 - 0.09 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PHD PF00628.29 KXT05424.1 - 0.0032 17.3 7.7 0.0032 17.3 7.7 4.1 3 2 0 3 3 3 1 PHD-finger C1_2 PF03107.16 KXT05424.1 - 0.019 15.3 13.8 0.46 10.9 3.3 3.0 2 0 0 2 2 2 0 C1 domain zf-C4pol PF14260.6 KXT05424.1 - 0.045 14.2 0.4 0.045 14.2 0.4 3.9 2 1 1 3 3 3 0 C4-type zinc-finger of DNA polymerase delta C1_1 PF00130.22 KXT05424.1 - 5.9 6.9 18.8 0.37 10.7 2.3 4.0 5 0 0 5 5 5 0 Phorbol esters/diacylglycerol binding domain (C1 domain) p450 PF00067.22 KXT05426.1 - 0.00062 18.6 0.0 0.00073 18.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFAP1 PF06991.11 KXT05427.1 - 8.4e-65 218.6 35.5 8.4e-65 218.6 35.5 2.2 1 1 1 2 2 2 1 Microfibril-associated/Pre-mRNA processing Myb_DNA-binding PF00249.31 KXT05428.1 - 3.2e-15 56.1 0.3 5.8e-08 32.8 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXT05428.1 - 7.4e-12 45.3 0.0 1.7e-05 25.0 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 KXT05428.1 - 0.0004 20.4 0.0 0.15 12.1 0.0 2.3 2 0 0 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 KXT05428.1 - 0.0014 18.8 0.0 0.44 10.8 0.0 2.3 2 0 0 2 2 2 2 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 KXT05428.1 - 0.018 14.9 0.6 1.8 8.5 0.1 2.5 2 0 0 2 2 2 0 Myb DNA-binding like Whi5 PF08528.11 KXT05429.1 - 4.6e-11 42.1 0.0 8.1e-11 41.3 0.0 1.4 1 0 0 1 1 1 1 Whi5 like DUF1780 PF08682.10 KXT05429.1 - 0.085 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative endonuclease, protein of unknown function (DUF1780) BC10 PF06726.12 KXT05430.1 - 1.9e-11 44.0 7.3 3.1e-11 43.3 7.3 1.3 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 Gp_dh_C PF02800.20 KXT05432.1 - 1.9e-70 235.5 0.0 2.7e-70 235.0 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KXT05432.1 - 4.3e-37 126.5 0.1 1e-36 125.3 0.1 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 KXT05432.1 - 0.078 13.1 0.1 0.66 10.1 0.0 2.5 3 0 0 3 3 3 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 KXT05432.1 - 0.085 12.2 0.1 0.2 11.0 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Gp_dh_C PF02800.20 KXT05433.1 - 1.9e-70 235.5 0.0 2.7e-70 235.0 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KXT05433.1 - 4.3e-37 126.5 0.1 1e-36 125.3 0.1 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 KXT05433.1 - 0.078 13.1 0.1 0.66 10.1 0.0 2.5 3 0 0 3 3 3 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 KXT05433.1 - 0.085 12.2 0.1 0.2 11.0 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Raptor_N PF14538.6 KXT05435.1 - 4.2e-63 211.7 0.0 8.5e-63 210.7 0.0 1.6 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain PIF1 PF05970.14 KXT05435.1 - 3.3e-36 125.2 0.0 2e-25 89.7 0.0 2.7 2 1 1 3 3 3 2 PIF1-like helicase AAA_30 PF13604.6 KXT05435.1 - 6.7e-22 78.2 0.0 1.1e-19 71.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KXT05435.1 - 5.5e-12 46.2 0.0 1.4e-11 44.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain WD40 PF00400.32 KXT05435.1 - 2.1e-09 37.9 2.5 1.5 9.8 0.0 7.2 8 0 0 8 8 6 2 WD domain, G-beta repeat Herpes_Helicase PF02689.14 KXT05435.1 - 1.5e-07 29.8 0.5 1.7e-05 23.0 0.0 2.4 3 0 0 3 3 3 1 Helicase UvrD_C_2 PF13538.6 KXT05435.1 - 1.9e-05 24.4 0.0 0.00041 20.1 0.0 2.7 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 KXT05435.1 - 2.9e-05 23.9 0.0 0.089 12.5 0.0 2.7 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 KXT05435.1 - 4.6e-05 23.7 0.0 0.00013 22.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KXT05435.1 - 0.00016 21.7 0.0 0.00037 20.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) HEAT PF02985.22 KXT05435.1 - 0.00036 20.5 4.1 0.1 12.9 0.0 4.5 5 0 0 5 5 3 1 HEAT repeat MeaB PF03308.16 KXT05435.1 - 0.0012 17.9 0.1 0.0022 17.1 0.1 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB BBS2_Mid PF14783.6 KXT05435.1 - 0.002 18.2 0.0 0.024 14.7 0.0 2.7 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region Atx10homo_assoc PF09759.9 KXT05435.1 - 0.0045 17.0 0.1 0.011 15.8 0.1 1.6 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain AAA_16 PF13191.6 KXT05435.1 - 0.014 15.8 0.1 0.076 13.4 0.0 2.4 2 0 0 2 2 1 0 AAA ATPase domain TrwB_AAD_bind PF10412.9 KXT05435.1 - 0.014 14.3 0.1 0.026 13.4 0.1 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ABC_tran PF00005.27 KXT05435.1 - 0.024 15.1 0.0 0.18 12.3 0.0 2.4 2 0 0 2 2 2 0 ABC transporter AAA PF00004.29 KXT05435.1 - 0.027 14.9 0.0 0.056 13.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KXT05435.1 - 0.034 14.2 0.0 0.16 12.0 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 KXT05435.1 - 0.037 13.5 0.0 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 KXT05435.1 - 0.048 12.8 0.0 0.093 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PhoH PF02562.16 KXT05435.1 - 0.061 12.8 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein NTPase_1 PF03266.15 KXT05435.1 - 0.062 13.2 0.1 0.45 10.4 0.1 2.2 2 0 0 2 2 2 0 NTPase ATPase_2 PF01637.18 KXT05435.1 - 0.062 13.2 0.0 0.19 11.6 0.0 1.7 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea DEAD PF00270.29 KXT05435.1 - 0.12 12.2 0.1 0.92 9.2 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_24 PF13479.6 KXT05435.1 - 0.16 11.7 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain tRNA-synt_1c PF00749.21 KXT05437.1 - 2.7e-91 305.7 0.0 5.8e-53 179.8 0.0 3.2 1 1 2 3 3 3 3 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KXT05437.1 - 1.5e-33 116.1 0.0 3.8e-33 114.8 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain CCDC53 PF10152.9 KXT05437.1 - 3 8.3 4.2 4.4 7.7 0.0 2.5 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex Chitin_synth_2 PF03142.15 KXT05438.1 - 1.2e-27 96.7 2.4 1.4e-23 83.4 1.4 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KXT05438.1 - 3e-15 56.7 2.6 3e-15 56.7 2.6 2.4 2 1 1 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KXT05438.1 - 8.6e-13 48.7 0.0 1.9e-12 47.6 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KXT05438.1 - 0.00081 19.2 0.1 0.04 13.7 0.1 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 RdRP PF05183.12 KXT05439.1 - 2.1e-98 330.5 0.0 3.2e-98 329.9 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase LysM PF01476.20 KXT05440.1 - 0.00031 20.7 0.0 0.00051 20.0 0.0 1.4 1 0 0 1 1 1 1 LysM domain UBA_4 PF14555.6 KXT05440.1 - 0.00082 19.1 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain Prok-RING_4 PF14447.6 KXT05440.1 - 0.05 13.5 6.0 0.26 11.2 6.0 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 TAP_C PF03943.13 KXT05440.1 - 0.051 13.2 0.1 0.051 13.2 0.1 1.7 2 0 0 2 2 2 0 TAP C-terminal domain zf-RanBP PF00641.18 KXT05440.1 - 0.081 12.3 3.7 0.19 11.1 3.7 1.6 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others zf-RING_5 PF14634.6 KXT05440.1 - 0.094 12.7 10.7 0.19 11.7 10.7 1.6 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 KXT05440.1 - 0.35 11.2 9.7 0.79 10.1 9.7 1.6 1 1 0 1 1 1 0 Ring finger domain GPR15L PF15854.5 KXT05440.1 - 0.46 10.8 3.9 0.96 9.7 3.9 1.5 1 0 0 1 1 1 0 G-protein coupled receptor ligand 15 FYVE PF01363.21 KXT05440.1 - 1.8 8.8 8.3 4.3 7.6 8.3 1.6 1 1 0 1 1 1 0 FYVE zinc finger zf-C3HC4_3 PF13920.6 KXT05440.1 - 9.4 6.2 13.8 97 2.9 13.8 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Glyco_transf_15 PF01793.16 KXT05441.1 - 3.2e-96 322.4 12.5 4e-95 318.8 12.5 2.0 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase ADH_N PF08240.12 KXT05443.1 - 2.2e-25 88.7 4.4 3.8e-25 87.9 4.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXT05443.1 - 5.8e-16 58.7 0.3 1.6e-15 57.3 0.1 1.9 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXT05443.1 - 0.0072 17.4 0.0 0.015 16.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase WYL_3 PF18488.1 KXT05443.1 - 0.0073 16.6 0.2 0.023 15.1 0.2 1.8 1 0 0 1 1 1 1 WYL domain ELFV_dehydrog PF00208.21 KXT05443.1 - 0.077 12.7 0.2 0.14 11.9 0.2 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.19 KXT05443.1 - 0.082 12.3 0.3 0.14 11.5 0.3 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADK PF00406.22 KXT05444.1 - 1.7e-61 206.7 0.1 2.6e-61 206.1 0.1 1.3 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KXT05444.1 - 3.6e-25 89.0 0.3 3.6e-25 89.0 0.3 1.5 2 0 0 2 2 1 1 AAA domain ADK_lid PF05191.14 KXT05444.1 - 1.6e-17 63.2 0.0 3.6e-17 62.1 0.0 1.7 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 KXT05444.1 - 4.6e-05 24.0 0.0 0.0001 22.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KXT05444.1 - 0.00017 21.8 0.0 0.0004 20.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 KXT05444.1 - 0.0014 18.3 0.2 0.0023 17.6 0.2 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Dynactin_p22 PF07426.11 KXT05444.1 - 0.04 13.8 1.6 0.073 12.9 0.1 2.0 2 0 0 2 2 2 0 Dynactin subunit p22 BLOC1_2 PF10046.9 KXT05444.1 - 0.05 13.9 0.4 0.13 12.6 0.4 1.7 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ABC_tran_CTD PF16326.5 KXT05444.1 - 0.065 13.5 0.0 0.24 11.7 0.0 1.9 1 0 0 1 1 1 0 ABC transporter C-terminal domain Paramyx_P_V_C PF03210.13 KXT05444.1 - 0.072 12.9 0.8 0.16 11.8 0.5 1.6 1 1 0 1 1 1 0 Paramyxovirus P/V phosphoprotein C-terminal Cytidylate_kin PF02224.18 KXT05444.1 - 0.076 12.7 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase Csm1_N PF18504.1 KXT05444.1 - 9 6.7 7.0 1.8 8.9 0.2 2.9 4 0 0 4 4 3 0 Csm1 N-terminal domain PUF PF00806.19 KXT05445.1 - 8.6e-59 192.1 8.3 4.7e-07 29.1 0.1 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Peptidase_C15 PF01470.17 KXT05445.1 - 0.16 12.1 0.0 0.4 10.8 0.0 1.6 1 0 0 1 1 1 0 Pyroglutamyl peptidase PUF PF00806.19 KXT05446.1 - 8.6e-59 192.1 8.3 4.7e-07 29.1 0.1 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Peptidase_C15 PF01470.17 KXT05446.1 - 0.16 12.1 0.0 0.4 10.8 0.0 1.6 1 0 0 1 1 1 0 Pyroglutamyl peptidase Mhr1 PF12829.7 KXT05447.1 - 1.1e-28 99.2 0.8 2.1e-28 98.2 0.1 1.9 2 0 0 2 2 2 1 Transcriptional regulation of mitochondrial recombination DUF4695 PF15766.5 KXT05447.1 - 2.9 8.2 10.4 2 8.6 1.5 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4695) SDF PF00375.18 KXT05448.1 - 6.2e-91 305.3 30.0 7.4e-91 305.1 30.0 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family CAAD PF14159.6 KXT05448.1 - 0.0034 17.2 0.3 0.0034 17.2 0.3 2.9 2 0 0 2 2 2 1 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase AMP-binding PF00501.28 KXT05449.1 - 2.3e-73 247.2 0.0 3.8e-73 246.5 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KXT05449.1 - 2.3e-62 210.5 0.0 5.4e-62 209.3 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.25 KXT05449.1 - 5.4e-52 176.1 1.9 4.4e-51 173.1 1.6 2.2 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT05449.1 - 4.9e-40 137.5 1.2 1.1e-39 136.4 1.2 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT05449.1 - 2.2e-21 76.6 0.9 8.4e-16 58.4 0.8 2.4 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 KXT05449.1 - 8.4e-18 64.7 0.0 2.8e-10 40.1 0.0 3.2 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KXT05449.1 - 1.7e-12 47.5 0.0 4.8e-12 46.1 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site NAD_binding_10 PF13460.6 KXT05449.1 - 6.2e-10 39.3 1.2 1.2e-05 25.2 0.7 3.6 4 0 0 4 4 4 2 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KXT05449.1 - 1.1e-08 34.6 1.0 0.00026 20.2 0.2 2.8 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KXT05449.1 - 3.1e-08 33.0 0.0 4.8e-06 25.8 0.0 2.9 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KXT05449.1 - 3.4e-08 32.9 0.4 0.00014 21.1 0.0 3.1 2 1 0 2 2 2 2 RmlD substrate binding domain AMP-binding_C PF13193.6 KXT05449.1 - 0.0021 19.0 0.0 0.0089 17.0 0.0 2.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain NmrA PF05368.13 KXT05449.1 - 0.0037 16.8 1.3 22 4.5 0.0 4.0 4 0 0 4 4 4 0 NmrA-like family GDP_Man_Dehyd PF16363.5 KXT05449.1 - 0.0064 15.9 0.0 2.8 7.3 0.0 2.4 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase ApbA PF02558.16 KXT05449.1 - 0.023 14.4 0.1 0.11 12.1 0.1 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA DFP PF04127.15 KXT05449.1 - 0.07 13.0 1.1 0.21 11.4 0.6 2.0 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein DUF5353 PF17304.2 KXT05450.1 - 1.9e-33 114.0 5.6 2.6e-33 113.6 5.6 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5353) V-ATPase_G_2 PF16999.5 KXT05450.1 - 0.00012 22.4 14.9 0.0002 21.7 14.9 1.3 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit Borrelia_P83 PF05262.11 KXT05450.1 - 0.068 11.6 14.0 0.089 11.3 14.0 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Vicilin_N PF04702.12 KXT05450.1 - 0.12 12.2 11.6 0.16 11.8 11.6 1.1 1 0 0 1 1 1 0 Vicilin N terminal region DUF1451 PF07295.11 KXT05450.1 - 0.12 12.4 7.1 0.17 11.9 7.1 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain DUF3087 PF11286.8 KXT05450.1 - 0.13 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) Thioredoxin_14 PF18402.1 KXT05450.1 - 0.15 12.0 4.1 0.12 12.3 2.6 1.4 1 1 0 1 1 1 0 Thioredoxin-like domain Bacteriocin_IIc PF10439.9 KXT05450.1 - 0.25 11.5 3.7 0.4 10.8 3.7 1.2 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide ALMT PF11744.8 KXT05450.1 - 0.26 10.1 3.9 0.32 9.8 3.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter AAA_11 PF13086.6 KXT05450.1 - 0.44 10.3 5.4 0.55 10.0 5.4 1.2 1 0 0 1 1 1 0 AAA domain ETRAMP PF09716.10 KXT05450.1 - 0.66 10.1 5.9 3.8 7.7 5.9 2.1 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) HSP70 PF00012.20 KXT05450.1 - 0.68 8.0 11.6 0.83 7.8 11.6 1.0 1 0 0 1 1 1 0 Hsp70 protein Presenilin PF01080.17 KXT05450.1 - 0.77 8.4 4.8 0.81 8.4 4.8 1.2 1 0 0 1 1 1 0 Presenilin MCU PF04678.13 KXT05450.1 - 0.79 9.8 9.3 2.2 8.3 0.4 2.1 1 1 1 2 2 2 0 Mitochondrial calcium uniporter KfrA_N PF11740.8 KXT05450.1 - 1.6 9.4 10.8 0.78 10.4 3.7 2.4 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term CbtA PF09490.10 KXT05450.1 - 4.5 7.0 11.3 32 4.2 11.3 2.0 1 1 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) IFT57 PF10498.9 KXT05451.1 - 0.0051 15.8 2.8 0.0051 15.8 2.8 1.7 2 0 0 2 2 2 1 Intra-flagellar transport protein 57 BLOC1_2 PF10046.9 KXT05451.1 - 0.0052 17.0 7.2 0.31 11.4 1.0 3.5 1 1 4 5 5 5 3 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.11 KXT05451.1 - 0.011 15.9 6.0 0.56 10.5 0.6 3.0 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) HNF-1A_C PF04813.12 KXT05451.1 - 0.032 15.0 0.2 1.4 9.7 0.0 2.6 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus GCN5L1 PF06320.13 KXT05451.1 - 0.042 14.0 4.8 0.15 12.2 0.3 2.4 1 1 1 2 2 2 0 GCN5-like protein 1 (GCN5L1) EzrA PF06160.12 KXT05451.1 - 0.072 11.3 6.5 0.19 9.9 5.0 2.0 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA TPR_MLP1_2 PF07926.12 KXT05451.1 - 0.083 13.0 9.1 0.39 10.8 0.5 3.0 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 KXT05451.1 - 0.15 11.4 3.2 0.3 10.4 3.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 KXT05451.1 - 0.23 10.5 7.4 0.23 10.5 6.1 1.7 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Speriolin_C PF15059.6 KXT05451.1 - 0.24 11.5 1.1 3.2 7.9 0.0 2.3 1 1 1 2 2 2 0 Speriolin C-terminus Laminin_II PF06009.12 KXT05451.1 - 0.36 10.9 8.4 0.29 11.1 1.0 2.4 1 1 1 2 2 2 0 Laminin Domain II OmpH PF03938.14 KXT05451.1 - 0.64 10.4 6.7 5.4 7.4 6.7 2.3 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1759 PF03564.15 KXT05451.1 - 0.71 9.8 3.9 1.3 9.0 0.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) DMPK_coil PF08826.10 KXT05451.1 - 0.81 9.9 4.8 2.4 8.3 0.2 3.2 3 0 0 3 3 3 0 DMPK coiled coil domain like Spc7 PF08317.11 KXT05451.1 - 0.98 8.2 10.3 1.9 7.3 10.3 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein Occludin_ELL PF07303.13 KXT05451.1 - 1.8 9.3 7.1 2.4 8.9 2.2 2.9 1 1 2 3 3 3 0 Occludin homology domain UPF0242 PF06785.11 KXT05451.1 - 2 8.5 11.4 0.2 11.7 4.7 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Syntaxin_2 PF14523.6 KXT05451.1 - 4.7 7.6 6.9 25 5.3 1.9 2.6 2 1 0 2 2 2 0 Syntaxin-like protein V_ATPase_I PF01496.19 KXT05451.1 - 8.3 4.2 10.9 2.7 5.8 7.3 1.6 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Rhomboid PF01694.22 KXT05452.1 - 2.7e-34 118.3 7.9 2.7e-34 118.3 7.9 1.6 2 0 0 2 2 2 1 Rhomboid family DUF4956 PF16316.5 KXT05452.1 - 0.11 12.2 0.1 0.23 11.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4956) Pyr_redox_2 PF07992.14 KXT05453.1 - 4.3e-52 177.2 0.0 5.5e-52 176.8 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXT05453.1 - 1.1e-10 41.9 0.0 3.3e-09 37.2 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXT05453.1 - 0.0028 17.0 0.2 1.9 7.7 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NumbF PF06311.12 KXT05453.1 - 0.088 13.4 1.5 0.22 12.1 1.5 1.7 1 0 0 1 1 1 0 NUMB domain FPP PF05911.11 KXT05454.1 - 0.14 10.4 2.8 0.18 10.0 2.8 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil NYD-SP28_assoc PF14775.6 KXT05454.1 - 1.3 9.2 4.8 10 6.3 0.8 2.7 2 0 0 2 2 2 0 Sperm tail C-terminal domain HALZ PF02183.18 KXT05454.1 - 1.6 9.0 4.0 3.1 8.1 0.7 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper Seryl_tRNA_N PF02403.22 KXT05454.1 - 1.7 8.9 5.9 0.53 10.5 2.9 1.6 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain RNA_pol_Rpc4 PF05132.14 KXT05455.1 - 4.5e-29 101.8 0.3 4.5e-29 101.8 0.3 3.9 3 1 0 3 3 3 1 RNA polymerase III RPC4 OPT PF03169.15 KXT05456.1 - 4e-173 577.4 54.1 4.6e-173 577.2 54.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DNA_ligase_A_M PF01068.21 KXT05457.1 - 4.5e-44 150.6 0.2 1.8e-43 148.5 0.0 2.1 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KXT05457.1 - 5.1e-44 150.6 0.0 1.4e-43 149.2 0.0 1.8 2 0 0 2 2 2 1 DNA ligase N terminus BRCT_2 PF16589.5 KXT05457.1 - 7.5e-21 74.3 0.0 4e-15 56.0 0.0 2.9 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain DNA_ligase_A_C PF04679.15 KXT05457.1 - 6.6e-18 65.1 0.0 2.2e-17 63.5 0.0 2.0 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KXT05457.1 - 1.4e-15 58.0 0.0 2.8e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 RNA ligase LIG3_BRCT PF16759.5 KXT05457.1 - 1.2e-08 35.1 0.0 0.004 17.4 0.0 2.5 2 0 0 2 2 2 2 DNA ligase 3 BRCT domain BRCT PF00533.26 KXT05457.1 - 1.2e-07 32.0 0.0 1.2e-05 25.5 0.0 2.8 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 KXT05457.1 - 0.029 14.2 0.0 0.4 10.6 0.0 2.4 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain VPS13 PF16908.5 KXT05457.1 - 0.042 13.7 0.1 0.77 9.5 0.0 2.2 2 0 0 2 2 2 0 Vacuolar sorting-associated protein 13, N-terminal mRNA_cap_enzyme PF01331.19 KXT05457.1 - 0.11 12.3 0.9 0.32 10.8 0.3 2.2 2 1 0 2 2 2 0 mRNA capping enzyme, catalytic domain DUF1639 PF07797.14 KXT05457.1 - 2.1 8.4 7.3 8.2 6.5 7.3 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1639) Amidase PF01425.21 KXT05458.1 - 5.7e-85 286.0 0.0 7e-85 285.7 0.0 1.0 1 0 0 1 1 1 1 Amidase Tyr-DNA_phospho PF06087.12 KXT05461.1 - 4.7e-90 302.5 0.0 9e-90 301.6 0.0 1.5 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase CPSF73-100_C PF11718.8 KXT05461.1 - 1.1e-79 267.0 0.0 1.7e-79 266.3 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 KXT05461.1 - 1e-27 96.6 0.0 2.9e-27 95.1 0.0 1.8 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.27 KXT05461.1 - 4.8e-18 65.9 0.4 1e-17 64.8 0.4 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 KXT05461.1 - 7.4e-17 61.4 0.1 1.5e-16 60.4 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 KXT05461.1 - 5.1e-10 39.1 0.0 1.3e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_3 PF13483.6 KXT05461.1 - 0.00027 20.9 0.2 0.0013 18.6 0.2 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 KXT05461.1 - 0.00066 19.3 0.4 0.0032 17.0 0.2 2.2 2 1 0 2 2 2 1 Beta-lactamase superfamily domain PLDc_2 PF13091.6 KXT05461.1 - 0.0025 17.7 0.1 0.013 15.4 0.0 2.1 2 0 0 2 2 2 1 PLD-like domain UIM PF02809.20 KXT05461.1 - 0.014 15.3 1.5 0.045 13.7 1.5 2.0 1 0 0 1 1 1 0 Ubiquitin interaction motif Arrestin_C PF02752.22 KXT05462.1 - 6.1e-21 75.3 0.0 2e-20 73.6 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KXT05462.1 - 9.2e-07 29.0 0.0 0.00021 21.4 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain CRF PF00473.17 KXT05462.1 - 0.15 12.1 0.3 26 5.0 0.0 2.4 2 0 0 2 2 2 0 Corticotropin-releasing factor family Cellulase PF00150.18 KXT05463.1 - 3.5e-30 105.4 2.1 4.8e-30 105.0 2.1 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF5337 PF17272.2 KXT05463.1 - 0.11 12.4 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5337) Cellulase PF00150.18 KXT05464.1 - 2.2e-30 106.0 2.1 3e-30 105.6 2.1 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) XPG_I PF00867.18 KXT05469.1 - 9.4e-25 86.8 0.0 1.7e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KXT05469.1 - 0.0088 16.5 0.0 0.019 15.5 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain HsdM_N PF12161.8 KXT05469.1 - 0.073 13.7 0.0 0.17 12.5 0.0 1.6 1 0 0 1 1 1 0 HsdM N-terminal domain FA_hydroxylase PF04116.13 KXT05471.1 - 8.3e-23 81.2 13.5 8.3e-23 81.2 13.5 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily 4HBT_3 PF13622.6 KXT05474.1 - 0.025 14.8 0.2 0.043 14.1 0.2 1.3 1 0 0 1 1 1 0 Thioesterase-like superfamily BCDHK_Adom3 PF10436.9 KXT05475.1 - 1.7e-43 148.3 0.1 2.4e-43 147.8 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KXT05475.1 - 1.3e-08 35.3 0.3 1.6e-06 28.6 0.3 3.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Abhydrolase_3 PF07859.13 KXT05476.1 - 1.7e-35 122.8 0.0 5.3e-34 117.9 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXT05476.1 - 0.0057 15.6 0.1 0.0076 15.2 0.1 1.3 1 1 0 1 1 1 1 Carboxylesterase family DUF1772 PF08592.11 KXT05477.1 - 1.2e-12 48.4 1.3 1.4e-12 48.1 1.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) DUF4149 PF13664.6 KXT05477.1 - 0.032 14.6 0.8 0.078 13.3 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) Thiolase_N PF00108.23 KXT05478.1 - 5.1e-64 216.1 0.0 6.4e-64 215.8 0.0 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXT05478.1 - 4.9e-42 142.5 0.1 9.3e-42 141.6 0.1 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KXT05478.1 - 0.01 15.4 0.4 0.022 14.3 0.1 1.6 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KXT05478.1 - 0.047 13.5 0.2 3 7.8 0.0 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III TAF4 PF05236.14 KXT05479.1 - 4e-24 85.8 20.0 1.1e-22 81.1 20.0 2.8 1 1 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family DUF4554 PF15091.6 KXT05479.1 - 0.56 9.0 6.8 1.2 8.0 6.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) MFS_1 PF07690.16 KXT05480.1 - 1.3e-40 139.4 31.3 1.3e-40 139.4 31.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily IF-2B PF01008.17 KXT05481.1 - 1.4e-76 257.4 0.0 1.9e-76 257.0 0.0 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family TFIIA PF03153.13 KXT05481.1 - 1.1 9.1 19.3 1.5 8.8 19.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1387 PF07139.11 KXT05481.1 - 9.9 5.8 14.1 17 5.0 14.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) S1-P1_nuclease PF02265.16 KXT05482.1 - 8.7e-64 215.8 0.1 1.1e-63 215.4 0.1 1.1 1 0 0 1 1 1 1 S1/P1 Nuclease DUF697 PF05128.12 KXT05482.1 - 0.16 11.7 0.1 0.27 10.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF697) PTCB-BRCT PF12738.7 KXT05484.1 - 2.1e-38 130.0 0.2 5.5e-21 74.3 0.0 3.4 3 0 0 3 3 3 3 twin BRCT domain BRCT PF00533.26 KXT05484.1 - 2.2e-26 92.0 0.2 2.1e-13 50.5 0.0 4.4 5 0 0 5 5 5 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KXT05484.1 - 3.1e-11 43.5 0.0 0.00019 21.8 0.0 4.1 4 0 0 4 4 4 2 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KXT05484.1 - 7e-06 26.2 0.1 0.082 13.2 0.0 3.5 3 0 0 3 3 3 2 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 KXT05484.1 - 0.00011 22.2 0.0 0.15 12.2 0.0 2.7 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 KXT05484.1 - 0.0017 18.2 0.0 2.3 8.2 0.0 2.8 2 1 1 3 3 3 2 Regulator of Ty1 transposition protein 107 BRCT domain WD40 PF00400.32 KXT05494.1 - 0.0027 18.5 2.7 5.6 8.0 0.2 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat DUF3432 PF11914.8 KXT05494.1 - 0.11 12.7 1.5 0.21 11.8 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) Y_phosphatase PF00102.27 KXT05495.1 - 1.6e-59 201.3 2.3 5.7e-52 176.6 0.6 3.3 2 1 0 2 2 2 2 Protein-tyrosine phosphatase Rhodanese PF00581.20 KXT05495.1 - 2.8e-11 43.9 0.0 2.4e-10 40.9 0.0 2.3 2 0 0 2 2 2 1 Rhodanese-like domain DSPc PF00782.20 KXT05495.1 - 0.0042 16.9 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KXT05495.1 - 0.013 15.4 0.0 0.029 14.3 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family CCAP PF11105.8 KXT05495.1 - 0.087 12.8 0.1 0.27 11.2 0.1 1.8 1 0 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a Med17 PF10156.9 KXT05496.1 - 2.8e-78 263.7 0.0 3.6e-78 263.3 0.0 1.0 1 0 0 1 1 1 1 Subunit 17 of Mediator complex ABM PF03992.16 KXT05497.1 - 0.0056 16.8 0.6 0.01 16.0 0.6 1.4 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Melibiase_2 PF16499.5 KXT05498.1 - 4e-42 144.3 0.6 6.5e-42 143.7 0.6 1.3 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 KXT05498.1 - 3.2e-13 49.6 0.1 9.4e-13 48.0 0.1 1.9 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KXT05498.1 - 0.049 12.6 0.0 0.13 11.2 0.0 1.6 2 0 0 2 2 2 0 Melibiase Melibiase_2 PF16499.5 KXT05500.1 - 4e-42 144.3 0.6 6.5e-42 143.7 0.6 1.3 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 KXT05500.1 - 3.2e-13 49.6 0.1 9.4e-13 48.0 0.1 1.9 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KXT05500.1 - 0.049 12.6 0.0 0.13 11.2 0.0 1.6 2 0 0 2 2 2 0 Melibiase Sulfotransfer_4 PF17784.1 KXT05501.1 - 1.9e-62 210.9 0.0 2.5e-62 210.5 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KXT05501.1 - 0.0014 19.0 0.1 0.0036 17.7 0.1 1.8 1 1 0 1 1 1 1 Sulfotransferase family Pkinase PF00069.25 KXT05502.1 - 1.1e-07 31.5 0.0 1.8e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain ISN1 PF06437.11 KXT05503.1 - 3.5e-195 648.7 0.0 3.9e-195 648.5 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase FtsK_SpoIIIE PF01580.18 KXT05503.1 - 0.069 12.5 0.0 1.4 8.2 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Pex24p PF06398.11 KXT05504.1 - 2.4e-83 280.2 3.0 3.4e-83 279.6 3.0 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Secretin PF00263.21 KXT05506.1 - 0.062 12.9 0.1 0.085 12.5 0.1 1.2 1 0 0 1 1 1 0 Bacterial type II and III secretion system protein NYN PF01936.18 KXT05507.1 - 1.6e-29 103.3 0.0 2.5e-29 102.7 0.0 1.3 1 0 0 1 1 1 1 NYN domain OST-HTH PF12872.7 KXT05507.1 - 1.4e-08 34.4 0.0 3e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 OST-HTH/LOTUS domain PIN7 PF18475.1 KXT05507.1 - 0.069 13.8 0.0 0.13 12.9 0.0 1.5 1 0 0 1 1 1 0 PIN domain F-box PF00646.33 KXT05508.1 - 4.3e-07 29.6 0.3 1.6e-06 27.9 0.3 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXT05508.1 - 0.0091 15.9 0.1 0.024 14.5 0.1 1.8 1 0 0 1 1 1 1 F-box-like Per1 PF04080.13 KXT05509.1 - 1.8e-104 349.0 10.1 2.2e-104 348.8 10.1 1.0 1 0 0 1 1 1 1 Per1-like family DUF3792 PF12670.7 KXT05509.1 - 1.1 9.5 4.3 0.3 11.2 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) Ank_2 PF12796.7 KXT05510.1 - 2.9e-30 104.7 1.3 3.3e-10 40.4 0.0 8.2 3 3 5 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXT05510.1 - 8.3e-26 90.0 4.2 8.7e-06 26.2 0.0 9.8 9 3 2 11 11 11 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXT05510.1 - 1.9e-20 70.7 11.3 0.015 15.7 0.0 12.8 14 0 0 14 14 14 5 Ankyrin repeat Ank_5 PF13857.6 KXT05510.1 - 2e-16 59.8 3.1 0.0028 17.9 0.0 8.9 7 1 3 10 10 10 5 Ankyrin repeats (many copies) Ank PF00023.30 KXT05510.1 - 3.5e-09 36.7 10.1 0.019 15.4 0.1 7.9 9 0 0 9 9 9 2 Ankyrin repeat Acetyltransf_CG PF14542.6 KXT05510.1 - 0.16 12.1 0.0 0.49 10.6 0.0 1.8 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase HlyIII PF03006.20 KXT05511.1 - 2.1e-66 223.9 15.6 2.5e-66 223.6 15.6 1.1 1 0 0 1 1 1 1 Haemolysin-III related Phage_Coat_Gp8 PF05371.12 KXT05511.1 - 0.065 13.0 0.0 0.25 11.1 0.0 2.0 2 0 0 2 2 2 0 Phage major coat protein, Gp8 DUF962 PF06127.11 KXT05511.1 - 0.17 12.0 2.9 0.42 10.7 2.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF962) MerC PF03203.14 KXT05511.1 - 2.1 8.8 17.4 2.6 8.5 4.0 2.8 1 1 1 3 3 3 0 MerC mercury resistance protein p450 PF00067.22 KXT05512.1 - 1.2e-72 245.2 0.0 1.4e-72 245.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fe-S_biosyn PF01521.20 KXT05513.1 - 2.6e-12 46.9 0.0 3e-10 40.3 0.0 2.2 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis Peptidase_S8 PF00082.22 KXT05513.1 - 0.073 12.3 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 Subtilase family Clathrin-link PF09268.10 KXT05513.1 - 0.2 11.1 0.1 0.33 10.4 0.1 1.3 1 0 0 1 1 1 0 Clathrin, heavy-chain linker Lipase_GDSL_2 PF13472.6 KXT05514.1 - 1.9e-14 54.5 0.2 1.2e-12 48.6 0.2 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXT05514.1 - 2.2e-06 27.8 0.0 3.9e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF554 PF04474.12 KXT05514.1 - 0.17 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF554) Lipase_GDSL_2 PF13472.6 KXT05515.1 - 1.2e-16 61.6 0.4 9.4e-14 52.2 0.0 2.2 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXT05515.1 - 1.5e-08 34.9 0.0 2.6e-08 34.1 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase fn3 PF00041.21 KXT05515.1 - 0.00018 21.7 0.6 0.73 10.2 0.1 3.3 3 0 0 3 3 3 2 Fibronectin type III domain Lipase_GDSL_3 PF14606.6 KXT05515.1 - 0.0013 18.9 0.0 0.0027 17.9 0.0 1.5 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_2 PF13472.6 KXT05516.1 - 8.7e-17 62.1 0.4 7.4e-14 52.5 0.0 2.2 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXT05516.1 - 1.1e-08 35.3 0.0 2e-08 34.5 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase fn3 PF00041.21 KXT05516.1 - 0.0002 21.7 0.8 0.61 10.5 0.1 3.3 3 0 0 3 3 3 2 Fibronectin type III domain Lipase_GDSL_3 PF14606.6 KXT05516.1 - 0.001 19.3 0.0 0.0021 18.2 0.0 1.5 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_2 PF13472.6 KXT05517.1 - 8.7e-17 62.1 0.4 7.4e-14 52.5 0.0 2.2 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXT05517.1 - 1.1e-08 35.3 0.0 2e-08 34.5 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase fn3 PF00041.21 KXT05517.1 - 0.0002 21.7 0.8 0.61 10.5 0.1 3.3 3 0 0 3 3 3 2 Fibronectin type III domain Lipase_GDSL_3 PF14606.6 KXT05517.1 - 0.001 19.3 0.0 0.0021 18.2 0.0 1.5 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_2 PF13472.6 KXT05518.1 - 8.7e-17 62.1 0.4 7.4e-14 52.5 0.0 2.2 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KXT05518.1 - 1.1e-08 35.3 0.0 2e-08 34.5 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase fn3 PF00041.21 KXT05518.1 - 0.0002 21.7 0.8 0.61 10.5 0.1 3.3 3 0 0 3 3 3 2 Fibronectin type III domain Lipase_GDSL_3 PF14606.6 KXT05518.1 - 0.001 19.3 0.0 0.0021 18.2 0.0 1.5 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family HLH PF00010.26 KXT05519.1 - 6.4e-08 32.4 0.0 1.2e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain BCOR PF15808.5 KXT05519.1 - 0.043 14.0 10.4 0.12 12.5 10.2 1.8 1 1 0 1 1 1 0 BCL-6 co-repressor, non-ankyrin-repeat region DUF4171 PF13775.6 KXT05519.1 - 0.99 9.9 10.9 2 8.9 10.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4171) Ank_2 PF12796.7 KXT05520.1 - 1.7e-38 131.1 20.3 5.6e-12 46.1 3.5 5.5 2 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXT05520.1 - 1.5e-30 105.1 15.4 2.9e-06 27.7 0.3 8.3 5 3 2 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXT05520.1 - 1.3e-23 80.5 12.9 0.06 13.9 0.1 10.7 11 0 0 11 11 11 7 Ankyrin repeat Ank_5 PF13857.6 KXT05520.1 - 4.9e-23 80.9 22.2 3.2e-06 27.3 0.3 7.5 5 2 3 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 KXT05520.1 - 2.2e-22 78.5 28.8 0.0017 18.8 0.1 10.4 11 0 0 11 11 11 8 Ankyrin repeat Abhydrolase_1 PF00561.20 KXT05521.1 - 1e-17 64.7 0.0 1.8e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXT05521.1 - 2.1e-14 54.7 0.0 6.4e-14 53.1 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXT05521.1 - 1.8e-08 33.9 0.0 9.7e-08 31.6 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF3530 PF12048.8 KXT05521.1 - 0.0015 18.0 0.0 0.0019 17.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3530) Abhydrolase_2 PF02230.16 KXT05521.1 - 0.018 14.8 0.0 0.35 10.6 0.0 2.4 2 1 0 3 3 3 0 Phospholipase/Carboxylesterase zf-C2H2_jaz PF12171.8 KXT05522.1 - 6.1e-05 23.2 1.2 0.00011 22.4 1.2 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXT05522.1 - 0.015 15.7 0.1 0.028 14.8 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-DBF PF07535.12 KXT05522.1 - 0.32 11.2 3.3 0.64 10.2 3.3 1.5 1 0 0 1 1 1 0 DBF zinc finger Sterol_MT_C PF08498.10 KXT05523.1 - 1e-29 102.6 0.5 1.7e-29 101.9 0.5 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 KXT05523.1 - 6.5e-21 74.8 0.0 1.6e-20 73.5 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXT05523.1 - 7.3e-19 68.3 0.0 2.3e-18 66.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXT05523.1 - 6.3e-16 58.5 0.0 9e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXT05523.1 - 5e-12 46.0 0.0 8e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KXT05523.1 - 1.1e-10 41.2 0.0 1.6e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 KXT05523.1 - 3.3e-10 39.7 0.0 5.3e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KXT05523.1 - 8e-09 36.1 0.0 1.5e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 KXT05523.1 - 1.2e-05 24.1 0.0 1.7e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PrmA PF06325.13 KXT05523.1 - 0.00025 20.5 0.0 0.00058 19.3 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 KXT05523.1 - 0.0011 18.8 0.0 0.0017 18.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.10 KXT05523.1 - 0.0014 18.3 0.0 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.14 KXT05523.1 - 0.0031 17.1 0.0 0.0058 16.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.20 KXT05523.1 - 0.006 15.7 0.0 0.0093 15.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_2 PF00891.18 KXT05523.1 - 0.014 14.7 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain MetW PF07021.12 KXT05523.1 - 0.017 14.8 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW RRP14 PF15459.6 KXT05523.1 - 0.12 13.0 2.5 0.32 11.6 2.5 1.6 1 0 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 Methyltransf_32 PF13679.6 KXT05523.1 - 0.17 11.9 0.1 0.35 10.8 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain SAC3_GANP PF03399.16 KXT05524.1 - 0.0012 18.3 0.1 0.0019 17.6 0.1 1.2 1 0 0 1 1 1 1 SAC3/GANP family HEPN_SAV_6107 PF18726.1 KXT05524.1 - 0.089 13.3 0.1 0.36 11.4 0.0 2.0 2 0 0 2 2 2 0 SAV_6107-like HEPN Myb_DNA-binding PF00249.31 KXT05525.1 - 2.2e-08 34.2 5.5 0.042 14.0 0.0 5.3 5 0 0 5 5 5 2 Myb-like DNA-binding domain HTH_38 PF13936.6 KXT05525.1 - 2.1e-07 30.6 0.1 0.054 13.3 0.0 3.8 3 0 0 3 3 3 2 Helix-turn-helix domain HTH_23 PF13384.6 KXT05525.1 - 8e-07 28.7 0.8 0.11 12.3 0.0 4.5 4 1 0 4 4 4 2 Homeodomain-like domain Terminase_5 PF06056.12 KXT05525.1 - 6.2e-06 26.0 0.1 0.089 12.7 0.0 3.9 4 0 0 4 4 4 1 Putative ATPase subunit of terminase (gpP-like) HTH_11 PF08279.12 KXT05525.1 - 9.1e-06 25.5 0.1 0.0038 17.1 0.0 2.9 2 0 0 2 2 2 1 HTH domain GcrA PF07750.11 KXT05525.1 - 1.8e-05 25.2 1.6 0.2 12.1 0.0 4.2 3 1 1 4 4 4 1 GcrA cell cycle regulator Sigma70_r4_2 PF08281.12 KXT05525.1 - 5.5e-05 22.8 0.5 0.29 10.8 0.0 4.3 5 0 0 5 5 5 1 Sigma-70, region 4 HTH_28 PF13518.6 KXT05525.1 - 0.0027 17.8 0.5 2.5 8.3 0.0 4.0 4 1 0 4 4 4 1 Helix-turn-helix domain HTH_24 PF13412.6 KXT05525.1 - 0.012 15.2 0.1 4.1 7.1 0.1 2.8 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.16 KXT05525.1 - 0.018 14.5 0.0 4.2 7.0 0.0 3.2 3 0 0 3 3 3 0 Sigma-70, region 4 Myb_DNA-bind_6 PF13921.6 KXT05525.1 - 0.029 14.6 1.8 20 5.5 0.0 4.2 4 1 0 4 4 4 0 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KXT05525.1 - 0.04 14.3 0.2 0.54 10.7 0.0 2.7 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain DUF1732 PF08340.11 KXT05525.1 - 0.054 13.5 0.1 7.4 6.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1732) HTH_Tnp_1 PF01527.20 KXT05525.1 - 0.07 13.4 0.4 15 6.0 0.0 3.0 3 0 0 3 3 3 0 Transposase Glyco_tranf_2_3 PF13641.6 KXT05526.1 - 5.3e-13 49.4 1.9 1.7e-11 44.4 1.8 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KXT05526.1 - 3.1e-12 46.3 0.3 6e-12 45.4 0.3 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.15 KXT05526.1 - 2.3e-10 39.8 6.7 4.1e-08 32.3 7.3 2.8 2 1 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.6 KXT05526.1 - 4.7e-07 29.9 16.9 4.7e-07 29.9 16.9 2.8 1 1 1 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KXT05526.1 - 0.007 16.2 0.0 0.39 10.5 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 2 DUF1691 PF07950.11 KXT05527.1 - 3.1e-37 127.6 4.8 8.1e-34 116.6 1.1 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF1691) DUF3185 PF11381.8 KXT05527.1 - 0.0026 17.7 0.0 0.016 15.2 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3185) TPT PF03151.16 KXT05528.1 - 4.6e-14 52.4 17.6 5.8e-14 52.1 17.6 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KXT05528.1 - 7.6e-05 22.9 8.3 7.6e-05 22.9 8.3 2.2 2 0 0 2 2 2 1 EamA-like transporter family DUF3318 PF11780.8 KXT05528.1 - 0.0063 16.5 0.5 0.061 13.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3318) DUF2235 PF09994.9 KXT05529.1 - 2.6e-74 250.2 0.0 3.3e-74 249.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Complex1_LYR PF05347.15 KXT05530.1 - 5.8e-07 29.5 0.0 1.1e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KXT05530.1 - 0.0013 19.4 0.0 0.0023 18.6 0.0 1.3 1 1 0 1 1 1 1 Complex1_LYR-like Peptidase_M90 PF06167.12 KXT05530.1 - 0.0043 16.7 0.1 0.0053 16.4 0.1 1.1 1 0 0 1 1 1 1 Glucose-regulated metallo-peptidase M90 p450 PF00067.22 KXT05531.1 - 3.1e-13 49.3 0.0 3.4e-13 49.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SOG2 PF10428.9 KXT05532.1 - 1.6 7.9 17.0 1.9 7.6 17.0 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein ERG2_Sigma1R PF04622.12 KXT05533.1 - 1.4e-94 315.3 0.6 1.7e-94 315.0 0.6 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein RRM_1 PF00076.22 KXT05534.1 - 4.4e-07 29.6 0.0 7.3e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KXT05534.1 - 0.0013 18.6 0.0 0.0025 17.8 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif PGM_PMM_I PF02878.16 KXT05536.1 - 1.1e-18 67.2 0.2 7.2e-08 32.2 0.0 3.1 1 1 2 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 KXT05536.1 - 3.5e-11 43.1 0.0 1.6e-10 41.0 0.0 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.16 KXT05536.1 - 4.2e-05 24.1 0.1 0.00023 21.7 0.1 2.4 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 KXT05536.1 - 0.002 18.3 0.2 0.014 15.6 0.2 2.2 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Amidase PF01425.21 KXT05537.1 - 2.7e-105 352.9 0.1 4.2e-105 352.3 0.1 1.2 1 0 0 1 1 1 1 Amidase TBP PF00352.21 KXT05538.1 - 5.3e-58 192.9 0.3 5.7e-32 109.5 0.0 2.7 2 1 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KXT05538.1 - 0.0092 16.1 0.0 1 9.6 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Tankyrase_bdg_C PF15327.6 KXT05539.1 - 0.014 15.8 1.8 0.049 14.1 1.8 1.9 1 0 0 1 1 1 0 Tankyrase binding protein C terminal domain TPR_11 PF13414.6 KXT05539.1 - 0.039 13.6 0.3 0.88 9.3 1.2 2.9 3 0 0 3 3 3 0 TPR repeat WASH-7_C PF14746.6 KXT05539.1 - 0.053 13.2 0.7 0.16 11.7 0.2 1.9 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal CK_II_beta PF01214.18 KXT05539.1 - 0.11 12.3 0.0 0.43 10.4 0.0 2.0 2 0 0 2 2 2 0 Casein kinase II regulatory subunit TPR_1 PF00515.28 KXT05539.1 - 1.3 8.9 3.4 64 3.6 0.6 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Prion PF00377.18 KXT05540.1 - 0.077 12.8 0.3 0.15 11.9 0.3 1.4 1 0 0 1 1 1 0 Prion/Doppel alpha-helical domain TTL PF03133.15 KXT05541.1 - 1.3e-56 191.9 0.0 1.8e-56 191.4 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KXT05541.1 - 1e-05 24.9 0.0 3.9e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 YheC/D like ATP-grasp Dala_Dala_lig_C PF07478.13 KXT05541.1 - 0.096 12.2 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus CRAL_TRIO PF00650.20 KXT05542.1 - 2e-10 40.6 0.0 3.1e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KXT05542.1 - 0.015 15.4 0.0 0.049 13.8 0.0 1.9 2 0 0 2 2 2 0 CRAL/TRIO, N-terminal domain Metallophos PF00149.28 KXT05543.1 - 3.6e-11 44.0 5.7 3.6e-11 44.0 3.9 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.18 KXT05543.1 - 0.063 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain HET PF06985.11 KXT05545.1 - 3.9e-36 124.6 0.1 6.5e-36 123.9 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Tyrosinase PF00264.20 KXT05546.1 - 4.4e-35 122.0 5.9 1.4e-34 120.3 5.9 1.7 1 1 0 1 1 1 1 Common central domain of tyrosinase YhhN PF07947.14 KXT05546.1 - 0.18 11.4 0.2 0.35 10.4 0.2 1.4 1 0 0 1 1 1 0 YhhN family Tyrosinase PF00264.20 KXT05547.1 - 3.7e-35 122.2 6.1 1.2e-34 120.6 6.1 1.7 1 1 0 1 1 1 1 Common central domain of tyrosinase YhhN PF07947.14 KXT05547.1 - 0.18 11.4 0.2 0.3 10.7 0.2 1.3 1 0 0 1 1 1 0 YhhN family DNA_pol_B PF00136.21 KXT05548.1 - 3.2e-118 395.3 0.2 4.8e-118 394.8 0.2 1.3 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 KXT05548.1 - 2.2e-62 210.1 0.0 6.3e-62 208.6 0.0 1.9 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 KXT05548.1 - 2.9e-42 145.0 0.0 6.4e-42 143.9 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 KXT05548.1 - 1.5e-24 85.9 7.9 1.5e-24 85.9 7.9 3.2 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal NCKAP5 PF15246.6 KXT05548.1 - 0.0056 16.3 0.3 0.015 15.0 0.3 1.6 1 0 0 1 1 1 1 Nck-associated protein 5, Peripheral clock protein Tnp_DNA_bind PF14706.6 KXT05548.1 - 0.086 12.7 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 Transposase DNA-binding ATP_synth_reg PF14960.6 KXT05548.1 - 0.18 11.3 0.1 0.41 10.2 0.1 1.5 1 0 0 1 1 1 0 ATP synthase regulation MmgE_PrpD PF03972.14 KXT05549.1 - 1.4e-116 389.7 0.0 1.6e-116 389.4 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Myc_N PF01056.18 KXT05549.1 - 0.13 12.1 0.0 0.39 10.6 0.0 1.7 2 0 0 2 2 2 0 Myc amino-terminal region N_formyltrans_C PF18216.1 KXT05549.1 - 0.15 11.8 0.3 0.42 10.3 0.3 1.8 1 0 0 1 1 1 0 N-formyltransferase dimerization C-terminal domain Ribosomal_L13e PF01294.18 KXT05550.1 - 4.6e-75 251.4 7.5 4.6e-75 251.4 7.5 1.4 2 0 0 2 2 2 1 Ribosomal protein L13e Na_Ca_ex PF01699.24 KXT05552.1 - 7.8e-38 129.8 41.6 7.1e-19 68.3 21.7 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Coilin_N PF15862.5 KXT05552.1 - 1.5 8.6 10.3 7.5 6.4 0.2 2.3 2 0 0 2 2 2 0 Coilin N-terminus Na_Ca_ex PF01699.24 KXT05554.1 - 7.8e-38 129.8 41.6 7.1e-19 68.3 21.7 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Coilin_N PF15862.5 KXT05554.1 - 1.5 8.6 10.3 7.5 6.4 0.2 2.3 2 0 0 2 2 2 0 Coilin N-terminus BTB PF00651.31 KXT05555.1 - 7.2e-06 26.2 0.0 0.00013 22.2 0.0 2.4 1 1 1 2 2 2 1 BTB/POZ domain HLH PF00010.26 KXT05556.1 - 1e-07 31.8 0.0 1.9e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Pox_E6 PF04656.12 KXT05556.1 - 0.026 13.0 0.0 0.035 12.5 0.0 1.1 1 0 0 1 1 1 0 Pox virus E6 protein HalX PF08663.10 KXT05556.1 - 0.082 13.2 1.5 0.11 12.8 0.4 1.7 2 0 0 2 2 2 0 HalX domain CENP-F_N PF10481.9 KXT05557.1 - 0.02 14.6 5.5 0.54 9.8 0.2 2.3 2 0 0 2 2 2 0 Cenp-F N-terminal domain DUF2046 PF09755.9 KXT05557.1 - 0.035 13.3 1.3 0.53 9.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) SlyX PF04102.12 KXT05557.1 - 0.15 12.7 5.0 11 6.7 2.8 2.7 2 0 0 2 2 2 0 SlyX End3 PF12761.7 KXT05557.1 - 0.19 11.9 3.1 5.4 7.1 0.9 2.4 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Striatin PF08232.12 KXT05557.1 - 0.34 11.5 0.1 0.34 11.5 0.1 2.6 3 1 0 3 3 3 0 Striatin family DivIC PF04977.15 KXT05557.1 - 0.48 10.2 5.2 0.56 10.0 1.1 2.2 2 0 0 2 2 2 0 Septum formation initiator CENP-F_leu_zip PF10473.9 KXT05557.1 - 0.52 10.3 5.9 0.14 12.1 2.1 1.8 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HIP1_clath_bdg PF16515.5 KXT05557.1 - 0.95 10.1 6.7 13 6.5 2.0 2.3 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ETF_QO PF05187.13 KXT05558.1 - 2.1e-48 162.8 1.1 3.3e-48 162.1 1.1 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 KXT05558.1 - 9.7e-08 32.0 0.0 0.00028 20.6 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXT05558.1 - 6.9e-07 29.4 0.0 2.6e-06 27.5 0.0 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXT05558.1 - 2.1e-06 27.1 0.1 0.027 13.6 0.3 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KXT05558.1 - 4.7e-05 22.8 0.0 0.00014 21.2 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXT05558.1 - 0.00073 18.9 0.0 0.0096 15.2 0.0 2.0 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 KXT05558.1 - 0.00091 18.0 0.1 0.0014 17.4 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 KXT05558.1 - 0.0024 18.4 0.1 8.6 7.0 0.1 3.3 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXT05558.1 - 0.0028 17.7 0.0 0.0068 16.4 0.0 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KXT05558.1 - 0.0054 16.0 0.0 0.01 15.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KXT05558.1 - 0.009 15.3 0.1 0.013 14.7 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXT05558.1 - 0.014 14.8 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Fer4_7 PF12838.7 KXT05558.1 - 0.035 14.7 1.0 0.1 13.2 1.0 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain Trp_halogenase PF04820.14 KXT05558.1 - 0.061 12.2 0.0 0.15 10.9 0.0 1.6 2 0 0 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.12 KXT05558.1 - 0.074 12.1 0.2 0.11 11.6 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein RNase_H2-Ydr279 PF09468.10 KXT05559.1 - 4.5e-34 118.0 0.0 4.5e-34 118.0 0.0 2.3 2 1 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 KXT05559.1 - 4.6e-26 90.9 0.0 8.5e-26 90.0 0.0 1.5 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain DUF3237 PF11578.8 KXT05560.1 - 2.2e-29 102.2 0.0 2.5e-29 102.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Fungal_trans PF04082.18 KXT05562.1 - 5.2e-14 51.9 0.0 8.9e-14 51.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT05562.1 - 6.8e-08 32.5 6.5 1.1e-07 31.8 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Actin PF00022.19 KXT05563.1 - 4e-22 78.4 0.1 1.7e-19 69.8 0.0 3.2 3 1 0 3 3 3 2 Actin MreB_Mbl PF06723.13 KXT05563.1 - 0.081 11.7 0.0 10 4.8 0.0 2.2 2 0 0 2 2 2 0 MreB/Mbl protein ANAPC_CDC26 PF10471.9 KXT05563.1 - 7.3 7.5 7.7 7 7.6 1.8 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Cyt-b5 PF00173.28 KXT05564.1 - 5.2e-12 45.7 0.0 6.6e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PGM_PMM_I PF02878.16 KXT05565.1 - 1e-33 115.9 0.1 1.5e-33 115.4 0.1 1.2 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 KXT05565.1 - 4.6e-25 88.0 0.0 8e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KXT05565.1 - 4.5e-15 56.1 0.0 1.1e-14 54.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 KXT05565.1 - 3.1e-08 33.7 0.0 7.2e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Ferritin_2 PF13668.6 KXT05566.1 - 3.1e-19 69.5 0.0 5.3e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain Epimerase PF01370.21 KXT05567.1 - 6.7e-16 58.5 0.0 9.5e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXT05567.1 - 1.4e-09 37.9 0.1 7.2e-09 35.5 0.1 2.2 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KXT05567.1 - 2.3e-09 36.6 0.0 3.3e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KXT05567.1 - 2.5e-08 33.4 0.0 1.1e-06 28.0 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KXT05567.1 - 5.7e-06 26.3 0.0 8.9e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KXT05567.1 - 0.0011 19.0 0.0 0.002 18.1 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KXT05567.1 - 0.0029 16.8 0.0 0.0037 16.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KXT05567.1 - 0.0033 16.9 0.1 0.0095 15.4 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.13 KXT05567.1 - 0.018 14.6 0.0 0.034 13.7 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family Sacchrp_dh_NADP PF03435.18 KXT05567.1 - 0.022 15.0 0.0 0.05 13.9 0.0 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain RmlD_sub_bind PF04321.17 KXT05567.1 - 0.022 13.8 0.0 0.092 11.8 0.0 1.9 2 0 0 2 2 2 0 RmlD substrate binding domain Shikimate_DH PF01488.20 KXT05567.1 - 0.066 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glyco_hydro_16 PF00722.21 KXT05569.1 - 2.1e-14 53.4 0.1 2.9e-14 52.9 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Fungal_trans PF04082.18 KXT05570.1 - 2.7e-17 62.7 0.3 4.1e-17 62.1 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 KXT05570.1 - 3.1e-05 24.2 6.4 3.1e-05 24.2 6.4 3.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 KXT05570.1 - 3.8e-05 23.9 20.4 0.0061 17.0 9.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXT05570.1 - 8.4e-05 23.1 18.5 0.054 14.4 7.6 3.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KXT05570.1 - 0.015 15.7 5.6 0.04 14.3 5.6 1.8 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KXT05570.1 - 5.2 7.5 12.3 0.34 11.3 5.2 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Sugar_tr PF00083.24 KXT05571.1 - 4.2e-86 289.6 23.2 5.3e-86 289.3 23.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXT05571.1 - 3.4e-18 65.7 46.7 7.5e-17 61.3 25.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-RING_2 PF13639.6 KXT05572.1 - 5.1e-12 45.9 5.1 8.5e-12 45.2 5.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KXT05572.1 - 2.5e-10 39.9 1.8 4.7e-10 39.0 1.8 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KXT05572.1 - 2.1e-07 30.7 3.0 3.6e-07 30.0 3.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXT05572.1 - 3.1e-07 30.1 4.3 5.2e-07 29.4 4.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXT05572.1 - 6.5e-06 26.3 6.1 2.5e-05 24.5 6.0 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KXT05572.1 - 8.1e-06 25.6 3.7 1.9e-05 24.4 3.7 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KXT05572.1 - 0.00022 21.1 1.9 0.00039 20.3 1.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KXT05572.1 - 0.00098 19.1 4.0 0.002 18.1 4.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KXT05572.1 - 0.006 16.6 1.5 0.017 15.2 1.5 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KXT05572.1 - 0.015 15.1 2.0 0.026 14.4 2.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KXT05572.1 - 0.078 12.8 3.7 0.14 12.0 3.7 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 KXT05572.1 - 0.36 11.2 1.9 0.67 10.3 1.9 1.5 1 0 0 1 1 1 0 RING-like domain cwf21 PF08312.12 KXT05574.1 - 5.4 7.3 8.2 1.5 9.0 1.9 2.4 2 0 0 2 2 2 0 cwf21 domain Arylsulfotran_2 PF14269.6 KXT05575.1 - 6.6e-45 153.8 0.1 1e-44 153.1 0.1 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KXT05575.1 - 3.6e-19 68.9 0.0 1.4e-18 67.0 0.0 1.8 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Toprim_C_rpt PF13368.6 KXT05575.1 - 0.15 12.1 0.2 0.51 10.4 0.1 1.9 2 0 0 2 2 2 0 Topoisomerase C-terminal repeat RRM_1 PF00076.22 KXT05576.1 - 7.7e-16 57.7 0.1 8.5e-10 38.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXT05576.1 - 0.2 11.5 0.0 2.2 8.2 0.0 2.2 3 0 0 3 3 3 0 Occluded RNA-recognition motif RRM_1 PF00076.22 KXT05577.1 - 1.2e-18 66.7 0.1 7e-10 38.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXT05577.1 - 0.0023 17.8 0.0 1.9 8.4 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_1 PF00076.22 KXT05578.1 - 6.1e-21 74.0 0.0 9.4e-10 38.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KXT05578.1 - 0.017 14.9 0.0 2.4 8.1 0.0 2.4 3 0 0 3 3 3 0 Occluded RNA-recognition motif Epimerase PF01370.21 KXT05579.1 - 1.1e-16 61.1 0.1 3e-16 59.6 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXT05579.1 - 1.7e-13 50.8 0.0 2.4e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KXT05579.1 - 1.7e-12 46.9 0.0 2.5e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KXT05579.1 - 3.9e-11 42.6 0.0 5.7e-07 29.0 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 KXT05579.1 - 1.9e-10 40.7 0.1 3.1e-10 40.0 0.1 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KXT05579.1 - 8.7e-10 38.6 0.1 1.5e-09 37.8 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 KXT05579.1 - 1.1e-06 28.2 0.8 7.5e-06 25.5 0.1 2.1 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 KXT05579.1 - 4.1e-06 26.2 0.1 6e-06 25.6 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GFO_IDH_MocA PF01408.22 KXT05579.1 - 0.00099 19.9 0.1 0.047 14.5 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold RmlD_sub_bind PF04321.17 KXT05579.1 - 0.0056 15.8 0.1 0.065 12.3 0.0 2.2 2 0 0 2 2 2 1 RmlD substrate binding domain KR PF08659.10 KXT05579.1 - 0.017 15.0 0.4 0.58 10.0 0.4 2.3 1 1 0 1 1 1 0 KR domain Nrap_D6 PF17407.2 KXT05579.1 - 0.049 13.8 0.4 2.9 8.1 0.0 2.4 2 1 0 2 2 2 0 Nrap protein domain 6 His_Phos_2 PF00328.22 KXT05580.1 - 2.9e-12 46.6 0.0 1.5e-10 41.0 0.0 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) zf-primase PF09329.11 KXT05581.1 - 1.2e-19 69.8 1.4 2.3e-19 68.9 1.4 1.5 1 0 0 1 1 1 1 Primase zinc finger FlxA PF14282.6 KXT05581.1 - 0.0012 18.8 4.3 0.0012 18.8 4.3 3.0 3 0 0 3 3 3 1 FlxA-like protein WW PF00397.26 KXT05582.1 - 1.7e-11 44.0 1.9 4e-11 42.8 1.9 1.7 1 0 0 1 1 1 1 WW domain DUF3899 PF13038.6 KXT05582.1 - 0.0055 17.2 0.9 0.17 12.4 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3899) DUF2607 PF10795.9 KXT05582.1 - 0.03 14.4 0.6 0.063 13.4 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2607) p450 PF00067.22 KXT05583.1 - 0.0025 16.7 0.0 0.0028 16.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MRP-L28 PF09812.9 KXT05584.1 - 9.1e-08 32.4 2.3 2.7e-07 30.9 2.8 1.5 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L28 NADH5_C PF06455.11 KXT05604.1 - 0.16 11.5 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 NADH dehydrogenase subunit 5 C-terminus SKG6 PF08693.10 KXT05605.1 - 0.0071 15.7 0.1 0.012 15.0 0.1 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 KXT05605.1 - 0.055 13.2 0.0 0.17 11.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) Orf78 PF06024.12 KXT05605.1 - 0.18 12.1 0.0 0.56 10.5 0.0 1.8 1 0 0 1 1 1 0 Orf78 (ac78) 7TM_GPCR_Srv PF10323.9 KXT05605.1 - 0.25 10.7 0.0 0.43 9.9 0.0 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv SprT-like PF10263.9 KXT05606.1 - 0.043 13.7 0.5 0.24 11.3 0.5 2.0 1 1 0 1 1 1 0 SprT-like family p450 PF00067.22 KXT05607.1 - 3.4e-50 171.1 0.0 4.2e-50 170.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2205 PF10224.9 KXT05609.1 - 1.5e-34 117.8 0.7 2e-34 117.4 0.7 1.2 1 0 0 1 1 1 1 Short coiled-coil protein GST_N PF02798.20 KXT05610.1 - 2.7e-08 34.0 0.0 1e-07 32.2 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXT05610.1 - 7.7e-07 29.4 0.0 4e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KXT05610.1 - 1.3e-06 28.5 0.0 2e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXT05610.1 - 6.2e-06 26.3 0.0 1.2e-05 25.4 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KXT05610.1 - 2.5e-05 24.5 0.0 5.7e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXT05610.1 - 0.00091 19.2 0.0 0.0021 18.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KXT05610.1 - 0.011 16.3 0.0 0.02 15.5 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KXT05610.1 - 0.042 13.6 0.0 0.084 12.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain 2-Hacid_dh_C PF02826.19 KXT05611.1 - 4e-44 150.1 0.0 5.6e-44 149.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KXT05611.1 - 1.4e-05 25.3 0.7 2.1e-05 24.7 0.7 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh PF00389.30 KXT05611.1 - 1.6e-05 24.6 0.0 3e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.17 KXT05611.1 - 0.0067 17.0 0.2 0.018 15.6 0.1 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KXT05612.1 - 4e-44 150.1 0.0 5.6e-44 149.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KXT05612.1 - 1.4e-05 25.3 0.7 2.1e-05 24.7 0.7 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh PF00389.30 KXT05612.1 - 1.6e-05 24.6 0.0 3e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.17 KXT05612.1 - 0.0067 17.0 0.2 0.018 15.6 0.1 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KXT05613.1 - 4e-44 150.1 0.0 5.6e-44 149.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KXT05613.1 - 1.4e-05 25.3 0.7 2.1e-05 24.7 0.7 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh PF00389.30 KXT05613.1 - 1.6e-05 24.6 0.0 3e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.17 KXT05613.1 - 0.0067 17.0 0.2 0.018 15.6 0.1 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ADH_N PF08240.12 KXT05614.1 - 7.7e-26 90.1 1.7 1.7e-25 89.0 1.7 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXT05614.1 - 1.8e-14 53.8 0.0 2.8e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXT05614.1 - 1.5e-08 34.4 0.1 1.8e-06 27.6 0.2 2.2 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus UDPG_MGDP_dh_N PF03721.14 KXT05614.1 - 0.031 13.9 0.1 0.11 12.0 0.0 2.0 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PEP_mutase PF13714.6 KXT05615.1 - 1.2e-44 152.6 0.1 1.4e-44 152.3 0.1 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 KXT05615.1 - 1.3e-20 73.4 0.3 1.8e-20 72.9 0.3 1.1 1 0 0 1 1 1 1 Isocitrate lyase family S-methyl_trans PF02574.16 KXT05615.1 - 0.0085 15.9 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Fumerase_C PF05683.12 KXT05615.1 - 0.083 12.2 0.0 2.9 7.2 0.0 2.2 2 0 0 2 2 2 0 Fumarase C-terminus CHASE2 PF05226.11 KXT05615.1 - 0.1 12.3 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 CHASE2 domain Succ_CoA_lig PF13607.6 KXT05615.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain MARVEL PF01284.23 KXT05617.1 - 0.007 16.4 14.5 0.009 16.0 9.4 2.2 1 1 1 2 2 2 2 Membrane-associating domain SH3_9 PF14604.6 KXT05618.1 - 9.7e-13 47.8 0.0 2.3e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXT05618.1 - 8.5e-12 44.5 0.0 1.8e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain PH PF00169.29 KXT05618.1 - 3.3e-10 40.4 0.0 2.2e-09 37.8 0.0 2.2 1 1 0 1 1 1 1 PH domain SAM_2 PF07647.17 KXT05618.1 - 6.6e-10 38.9 0.0 1.2e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.17 KXT05618.1 - 2.2e-05 24.0 0.0 5.1e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.30 KXT05618.1 - 0.0053 17.2 0.0 0.0099 16.3 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_8 PF15409.6 KXT05618.1 - 0.12 12.7 0.0 0.45 10.8 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain DUF3431 PF11913.8 KXT05619.1 - 8.7e-75 251.2 0.6 1.1e-74 250.9 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) SLATT_fungal PF18142.1 KXT05620.1 - 0.11 12.5 0.2 0.16 12.0 0.2 1.2 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain ADH_zinc_N PF00107.26 KXT05623.1 - 9.4e-29 100.0 0.0 1.6e-28 99.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXT05623.1 - 6.4e-10 40.2 0.0 9.8e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXT05623.1 - 2.9e-05 23.9 0.0 0.00012 21.9 0.0 2.1 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 KXT05623.1 - 0.04 13.2 0.2 0.067 12.5 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 KXT05623.1 - 0.048 13.9 0.0 0.097 12.9 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain MJ1316 PF04457.12 KXT05625.1 - 3e-10 40.7 1.0 6.8e-10 39.6 1.0 1.6 1 0 0 1 1 1 1 MJ1316 RNA cyclic group end recognition domain DUF5305 PF17231.2 KXT05627.1 - 0.0096 15.3 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5305) TMEM154 PF15102.6 KXT05627.1 - 0.035 14.0 0.0 0.065 13.1 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family ASFV_J13L PF05568.11 KXT05627.1 - 0.044 13.6 0.0 0.066 13.0 0.0 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein Cadherin_C_2 PF16492.5 KXT05627.1 - 0.049 14.4 0.0 0.094 13.5 0.0 1.5 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal BatD PF13584.6 KXT05627.1 - 0.081 11.7 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance Gram_pos_anchor PF00746.21 KXT05627.1 - 0.098 12.6 0.4 0.17 11.9 0.4 1.4 1 0 0 1 1 1 0 LPXTG cell wall anchor motif zf-PHD-like PF15446.6 KXT05628.1 - 6.6e-67 224.3 12.3 6.6e-67 224.3 12.3 2.0 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.23 KXT05628.1 - 2.8e-54 184.2 0.0 4.4e-54 183.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-CCCH_6 PF18585.1 KXT05628.1 - 3.1e-27 94.2 0.6 7.4e-27 93.0 0.6 1.7 1 0 0 1 1 1 1 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 Helicase_C PF00271.31 KXT05628.1 - 2.7e-19 69.6 0.0 5.8e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KXT05628.1 - 1.1e-08 34.6 1.8 4.1e-08 32.7 1.8 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.24 KXT05628.1 - 1e-06 28.5 0.1 0.56 10.2 0.0 4.1 4 0 0 4 4 4 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 KXT05628.1 - 2.3e-05 24.5 0.0 4.7e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PHD PF00628.29 KXT05628.1 - 0.00012 21.9 13.9 0.00038 20.3 6.1 3.2 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 KXT05628.1 - 2.3 7.9 15.3 0.31 10.6 7.6 3.2 2 1 0 2 2 2 0 PHD-finger Peptidase_C1_2 PF03051.15 KXT05629.1 - 4.7e-158 526.6 0.0 5.4e-158 526.3 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 KXT05629.1 - 2.9e-07 30.8 0.2 0.0058 16.8 0.0 2.4 2 0 0 2 2 2 2 Papain family cysteine protease Inhibitor_I9 PF05922.16 KXT05630.1 - 0.0088 16.7 0.1 0.021 15.4 0.1 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 MFS_1 PF07690.16 KXT05631.1 - 6.4e-28 97.7 48.3 6.4e-28 97.7 48.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 KXT05634.1 - 3e-64 216.9 0.0 1.8e-63 214.4 0.0 2.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT05634.1 - 1.9e-36 125.7 0.0 2.3e-31 109.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KXT05634.1 - 1.4e-06 27.9 0.0 0.0032 16.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KXT05634.1 - 0.00033 20.6 0.1 0.00065 19.7 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KXT05634.1 - 0.014 14.4 0.1 0.022 13.7 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 KXT05634.1 - 0.038 13.6 0.0 0.072 12.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 KXT05634.1 - 0.043 13.2 0.0 0.076 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TrkH PF02386.16 KXT05636.1 - 2e-103 346.5 2.1 3.5e-97 326.0 0.4 2.0 2 0 0 2 2 2 2 Cation transport protein SieB PF14163.6 KXT05636.1 - 0.25 10.9 7.6 0.12 11.9 0.4 3.0 3 0 0 3 3 3 0 Super-infection exclusion protein B ABC_membrane PF00664.23 KXT05637.1 - 2.3e-33 116.0 13.2 4.1e-33 115.2 13.2 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KXT05637.1 - 4.5e-33 114.7 0.0 1.1e-32 113.4 0.0 1.7 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 KXT05637.1 - 5.6e-07 29.2 0.2 8.3e-06 25.4 0.0 2.1 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KXT05637.1 - 0.0046 17.2 0.4 0.049 13.9 0.4 2.4 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KXT05637.1 - 0.024 14.6 0.0 0.055 13.4 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 KXT05637.1 - 0.027 14.9 0.9 0.053 13.9 0.1 1.9 2 1 0 2 2 2 0 AAA ATPase domain SbcCD_C PF13558.6 KXT05637.1 - 0.028 14.6 0.6 0.61 10.4 0.6 2.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KXT05637.1 - 0.13 12.0 0.1 0.32 10.8 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 KXT05637.1 - 0.14 12.0 0.7 3 7.7 0.1 2.3 2 0 0 2 2 2 0 NTPase EMP70 PF02990.16 KXT05637.1 - 0.17 10.5 7.3 0.21 10.2 0.7 2.4 2 0 0 2 2 2 0 Endomembrane protein 70 AAA_5 PF07728.14 KXT05637.1 - 0.17 11.9 0.2 1.6 8.7 0.2 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) CH PF00307.31 KXT05638.1 - 2.6e-13 50.1 0.0 5e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain Sacchrp_dh_C PF16653.5 KXT05639.1 - 1.2e-73 248.5 0.0 1.7e-73 248.0 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 KXT05639.1 - 4.8e-20 72.2 0.5 7.7e-20 71.5 0.5 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KXT05639.1 - 1.2e-08 35.1 0.3 6.9e-08 32.6 0.3 2.0 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 KXT05639.1 - 9.7e-05 22.3 0.4 0.00022 21.2 0.3 1.5 1 1 0 1 1 1 1 NAD(P)H-binding F420_oxidored PF03807.17 KXT05639.1 - 0.00047 20.7 0.0 0.0012 19.4 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.6 KXT05639.1 - 0.032 14.7 0.1 0.066 13.7 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Semialdhyde_dh PF01118.24 KXT05639.1 - 0.098 13.1 0.3 0.62 10.5 0.1 2.4 3 1 1 4 4 4 0 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.18 KXT05639.1 - 0.13 12.5 1.1 0.16 12.3 0.2 1.6 2 0 0 2 2 2 0 TrkA-N domain Methyltransf_31 PF13847.6 KXT05640.1 - 1.8e-27 96.0 0.0 2.5e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXT05640.1 - 5.9e-20 71.8 0.0 9.7e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXT05640.1 - 2.4e-18 66.6 0.0 4.3e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXT05640.1 - 3.9e-15 56.4 0.0 7.3e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXT05640.1 - 1.2e-13 51.3 0.0 1.8e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXT05640.1 - 2.3e-11 43.5 0.0 3.3e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KXT05640.1 - 4.2e-11 42.7 0.0 5.9e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KXT05640.1 - 1.4e-09 37.6 0.0 3e-09 36.6 0.0 1.5 2 0 0 2 2 1 1 Putative methyltransferase PCMT PF01135.19 KXT05640.1 - 4.9e-06 26.4 0.0 2.4e-05 24.2 0.0 1.9 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.11 KXT05640.1 - 0.00016 20.7 0.0 0.0003 19.8 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) GCD14 PF08704.10 KXT05640.1 - 0.00017 21.4 0.0 0.00046 19.9 0.0 1.7 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_18 PF12847.7 KXT05640.1 - 0.00028 20.9 0.0 0.00044 20.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KXT05640.1 - 0.00055 19.6 0.0 0.00084 19.0 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 KXT05640.1 - 0.00057 19.9 0.0 0.00086 19.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KXT05640.1 - 0.00087 18.8 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 KXT05640.1 - 0.00092 19.4 0.0 0.0013 18.8 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase NodS PF05401.11 KXT05640.1 - 0.0029 17.2 0.0 0.0042 16.7 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_20 PF12147.8 KXT05640.1 - 0.013 14.7 0.0 0.018 14.2 0.0 1.1 1 0 0 1 1 1 0 Putative methyltransferase TehB PF03848.14 KXT05640.1 - 0.016 14.6 0.2 0.03 13.7 0.0 1.5 2 0 0 2 2 1 0 Tellurite resistance protein TehB tRNA_U5-meth_tr PF05958.11 KXT05640.1 - 0.017 14.2 0.0 0.024 13.7 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase UPF0020 PF01170.18 KXT05640.1 - 0.024 14.3 0.2 0.37 10.4 0.2 2.2 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Met_10 PF02475.16 KXT05640.1 - 0.026 14.3 0.0 0.033 13.9 0.0 1.1 1 0 0 1 1 1 0 Met-10+ like-protein DUF938 PF06080.12 KXT05640.1 - 0.03 14.1 0.0 0.043 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) CMAS PF02353.20 KXT05640.1 - 0.052 12.8 0.0 0.065 12.5 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_29 PF03141.16 KXT05640.1 - 0.1 11.2 0.0 1.6 7.2 0.0 2.0 1 1 1 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltr_RsmB-F PF01189.17 KXT05640.1 - 0.13 11.9 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F MethyltransfD12 PF02086.15 KXT05640.1 - 0.14 11.8 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase GidB PF02527.15 KXT05640.1 - 0.22 10.8 0.0 0.32 10.3 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Pkinase PF00069.25 KXT05641.1 - 7.8e-16 58.2 0.0 2.5e-15 56.5 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT05641.1 - 9.6e-09 34.9 0.0 1.8e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Aminotran_1_2 PF00155.21 KXT05642.1 - 1.8e-58 198.5 0.0 2.1e-58 198.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF4911 PF16256.5 KXT05642.1 - 0.094 12.7 0.0 3.9 7.5 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4911) Alliinase_C PF04864.13 KXT05642.1 - 0.15 10.9 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 Allinase Cys_Met_Meta_PP PF01053.20 KXT05642.1 - 0.2 10.2 0.0 0.32 9.5 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme 4HBT PF03061.22 KXT05643.1 - 1.7e-11 44.3 0.0 3e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily MaoC_dehydratas PF01575.19 KXT05643.1 - 0.11 12.1 0.0 0.27 10.8 0.0 1.7 2 0 0 2 2 2 0 MaoC like domain Na_H_Exchanger PF00999.21 KXT05644.1 - 2e-58 198.1 20.7 2.4e-58 197.8 20.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family RRM_1 PF00076.22 KXT05645.1 - 3e-10 39.8 0.0 0.00011 21.9 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.16 KXT05646.1 - 1e-23 83.8 16.7 1.4e-23 83.4 16.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1127 PF06568.11 KXT05646.1 - 0.16 11.7 0.1 0.37 10.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1127) Clr2_transil PF16761.5 KXT05647.1 - 1.2e-13 51.7 0.1 2.3e-13 50.7 0.1 1.5 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Clr2 PF10383.9 KXT05647.1 - 3.3e-08 34.4 0.0 1.8e-07 32.0 0.0 2.3 1 1 0 1 1 1 1 Transcription-silencing protein Clr2 p450 PF00067.22 KXT05648.1 - 3.4e-67 227.2 0.0 4.7e-67 226.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PhdYeFM_antitox PF02604.19 KXT05648.1 - 0.019 14.7 0.3 0.055 13.3 0.0 1.9 2 0 0 2 2 2 0 Antitoxin Phd_YefM, type II toxin-antitoxin system APH PF01636.23 KXT05649.1 - 1.2e-15 58.1 0.0 2e-15 57.4 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KXT05649.1 - 0.00021 20.7 0.0 0.018 14.4 0.0 2.1 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KXT05649.1 - 0.00039 19.5 0.0 0.00054 19.0 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 KXT05649.1 - 0.00054 19.6 0.0 0.00076 19.1 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KXT05649.1 - 0.00062 19.4 0.0 0.003 17.2 0.0 1.9 2 0 0 2 2 2 1 RIO1 family Pkinase PF00069.25 KXT05649.1 - 0.018 14.4 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Pkinase_Tyr PF07714.17 KXT05649.1 - 0.045 13.0 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Ran_BP1 PF00638.18 KXT05650.1 - 0.00021 21.6 0.0 0.00047 20.4 0.0 1.6 1 0 0 1 1 1 1 RanBP1 domain Nucleoporin_FG PF13634.6 KXT05650.1 - 0.00035 21.4 16.5 0.00035 21.4 16.5 11.5 3 3 5 9 9 9 2 Nucleoporin FG repeat region Di19_C PF14571.6 KXT05650.1 - 0.053 14.1 0.3 0.35 11.4 0.3 2.5 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal PBP1_TM PF14812.6 KXT05650.1 - 2.6 8.5 16.1 0.3 11.5 8.9 2.7 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SCP2 PF02036.17 KXT05651.1 - 3.4e-24 85.3 1.6 4e-24 85.0 1.6 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 KXT05651.1 - 7.8e-08 32.6 0.1 1e-07 32.3 0.1 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 KXT05651.1 - 0.064 13.7 0.0 0.079 13.4 0.0 1.2 1 0 0 1 1 1 0 Sterol carrier protein domain Ran_BP1 PF00638.18 KXT05652.1 - 0.00019 21.7 0.0 0.00044 20.5 0.0 1.6 1 0 0 1 1 1 1 RanBP1 domain Nucleoporin_FG PF13634.6 KXT05652.1 - 0.00035 21.4 16.6 0.00035 21.4 16.6 11.6 3 3 4 8 8 8 2 Nucleoporin FG repeat region Di19_C PF14571.6 KXT05652.1 - 0.046 14.2 0.3 0.33 11.5 0.3 2.5 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal PBP1_TM PF14812.6 KXT05652.1 - 2.3 8.7 16.1 0.28 11.6 8.9 2.7 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAA_hydrolase PF01557.18 KXT05653.1 - 5.1e-60 202.8 0.0 6.2e-60 202.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family AvrM_N PF18247.1 KXT05653.1 - 0.14 12.1 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 Flax-rust effector AvrM N-terminal domain DUF4588 PF15251.6 KXT05654.1 - 8e-08 32.4 2.6 3e-07 30.5 2.6 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) WD40 PF00400.32 KXT05656.1 - 3.3e-11 43.5 8.8 0.00023 21.9 0.2 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXT05656.1 - 3.2e-08 33.7 0.0 0.0014 18.9 0.0 3.0 1 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXT05656.1 - 1.2e-05 25.3 0.0 0.13 12.1 0.0 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Zn_ribbon_17 PF17120.5 KXT05656.1 - 1.6e-05 24.4 12.6 3.9e-05 23.2 12.6 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 KXT05656.1 - 0.0071 16.7 7.1 0.0071 16.7 7.1 2.5 2 0 0 2 2 2 1 Ring finger domain zinc_ribbon_16 PF17034.5 KXT05656.1 - 0.12 12.6 10.9 0.33 11.2 10.9 1.8 1 0 0 1 1 1 0 Zinc-ribbon like family zf-C3HC4 PF00097.25 KXT05656.1 - 1.5 8.8 12.0 3 7.8 2.9 2.8 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXT05656.1 - 9.7 6.6 11.7 79 3.6 11.7 2.4 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-MIZ PF02891.20 KXT05657.1 - 5.7e-09 35.6 0.7 1.1e-08 34.7 0.7 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger Glyco_hydro_16 PF00722.21 KXT05658.1 - 2.3e-43 147.7 5.1 3.6e-43 147.1 5.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Ribosomal_S21e PF01249.18 KXT05658.1 - 1.9e-41 140.1 0.1 3.2e-41 139.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S21e Chitin_bind_1 PF00187.19 KXT05658.1 - 2.7 8.5 20.6 0.2 12.1 14.2 2.3 1 1 1 2 2 2 0 Chitin recognition protein ubiquitin PF00240.23 KXT05661.1 - 8.1e-20 70.4 0.0 1.2e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 KXT05661.1 - 7.5e-08 32.1 0.1 1.6e-07 31.1 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.8 KXT05661.1 - 6.6e-07 29.1 0.0 1.2e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 KXT05661.1 - 1.5e-05 25.0 0.0 2.9e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KXT05661.1 - 0.00025 21.5 0.0 0.00047 20.7 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_2 PF14560.6 KXT05661.1 - 0.0031 18.0 0.0 0.0088 16.5 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain STI1 PF17830.1 KXT05661.1 - 0.041 13.8 27.4 0.25 11.3 3.7 3.5 2 1 1 3 3 3 0 STI1 domain HOIP-UBA PF16678.5 KXT05661.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 HOIP UBA domain pair YukD PF08817.10 KXT05661.1 - 0.19 12.4 0.0 0.76 10.5 0.0 2.1 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD GerD PF17898.1 KXT05661.1 - 0.83 9.6 7.4 1.2 9.1 1.5 2.5 2 1 0 2 2 2 0 Spore germination GerD central core domain ECH_1 PF00378.20 KXT05662.1 - 1.5e-09 37.6 0.0 1.8e-09 37.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Transketolase_C PF02780.20 KXT05663.1 - 0.15 12.0 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Transketolase, C-terminal domain 3HCDH_RFF PF18321.1 KXT05665.1 - 0.11 13.0 0.6 24 5.5 0.1 2.6 2 0 0 2 2 2 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain Pro_isomerase PF00160.21 KXT05669.1 - 3.5e-47 160.6 0.1 5e-47 160.1 0.1 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 KXT05669.1 - 7.2e-07 28.9 2.3 0.026 14.6 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KXT05669.1 - 0.00049 19.8 4.3 0.35 10.8 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KXT05669.1 - 0.0075 16.8 2.5 1.8 9.1 0.2 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXT05669.1 - 0.013 15.2 0.7 0.17 11.6 0.1 2.5 2 0 0 2 2 2 0 TPR repeat TPR_12 PF13424.6 KXT05669.1 - 0.02 15.2 0.3 6 7.2 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KXT05669.1 - 0.063 14.1 1.7 5.2 8.2 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXT05669.1 - 0.13 13.0 0.7 31 5.5 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat PI-PLC-X PF00388.19 KXT05670.1 - 5.3e-47 159.0 0.0 9.9e-47 158.2 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KXT05670.1 - 8.2e-39 132.5 0.0 1.3e-38 131.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 KXT05670.1 - 0.00046 20.4 0.0 0.0012 19.1 0.0 1.7 1 0 0 1 1 1 1 C2 domain MIP PF00230.20 KXT05672.1 - 9.9e-46 156.3 7.9 1.3e-45 155.9 7.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein CDC45 PF02724.14 KXT05674.1 - 1.5e-212 707.4 24.8 3.4e-196 653.4 0.0 3.8 1 1 3 4 4 4 2 CDC45-like protein TIMELESS_C PF05029.13 KXT05674.1 - 0.0054 16.0 1.3 0.0054 16.0 1.3 2.2 2 0 0 2 2 2 1 Timeless protein C terminal region CSRNP_N PF16019.5 KXT05674.1 - 0.48 10.3 5.5 1.4 8.8 5.5 1.7 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus BUD22 PF09073.10 KXT05674.1 - 0.51 9.6 34.1 0.094 12.0 15.1 2.1 2 0 0 2 2 2 0 BUD22 Nop14 PF04147.12 KXT05674.1 - 2.4 6.2 35.1 0.66 8.1 3.9 2.2 2 0 0 2 2 2 0 Nop14-like family FAM60A PF15396.6 KXT05674.1 - 6.3 6.8 11.7 0.45 10.5 5.4 2.1 2 0 0 2 2 2 0 Protein Family FAM60A Ras PF00071.22 KXT05675.1 - 2e-17 63.2 0.0 3e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXT05675.1 - 0.00011 22.5 0.0 0.00026 21.2 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 KXT05675.1 - 0.00093 19.2 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KXT05675.1 - 0.027 14.9 0.2 0.05 14.0 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain IIGP PF05049.13 KXT05675.1 - 0.041 13.0 0.0 0.062 12.3 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) RsgA_GTPase PF03193.16 KXT05675.1 - 0.094 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 KXT05675.1 - 0.12 12.2 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ras PF00071.22 KXT05676.1 - 2e-17 63.2 0.0 3e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXT05676.1 - 0.00011 22.5 0.0 0.00026 21.2 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 KXT05676.1 - 0.00093 19.2 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KXT05676.1 - 0.027 14.9 0.2 0.05 14.0 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain IIGP PF05049.13 KXT05676.1 - 0.041 13.0 0.0 0.062 12.3 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) RsgA_GTPase PF03193.16 KXT05676.1 - 0.094 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 KXT05676.1 - 0.12 12.2 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain F-box-like_2 PF13013.6 KXT05677.1 - 0.0059 16.6 0.2 0.015 15.2 0.2 1.9 1 1 0 1 1 1 1 F-box-like domain CFEM PF05730.11 KXT05678.1 - 2.3e-06 27.6 15.5 4.3e-06 26.7 15.5 1.5 1 0 0 1 1 1 1 CFEM domain Gamma-thionin PF00304.20 KXT05678.1 - 1.9 8.8 8.5 0.81 10.0 2.8 2.4 2 0 0 2 2 2 0 Gamma-thionin family RNase_H PF00075.24 KXT05679.1 - 1.2e-11 44.9 0.0 2.8e-11 43.8 0.0 1.5 1 1 0 1 1 1 1 RNase H MFS_1 PF07690.16 KXT05682.1 - 3.7e-19 68.9 37.2 1.5e-16 60.3 14.4 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily MRAP PF15183.6 KXT05682.1 - 0.11 12.4 0.0 0.77 9.7 0.0 2.2 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family MFS_1 PF07690.16 KXT05683.1 - 3.7e-19 68.9 37.2 1.5e-16 60.3 14.4 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily MRAP PF15183.6 KXT05683.1 - 0.11 12.4 0.0 0.77 9.7 0.0 2.2 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family Pyridoxal_deC PF00282.19 KXT05684.1 - 1.3e-53 182.1 0.0 2.4e-53 181.2 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KXT05684.1 - 0.00017 20.7 0.0 0.00026 20.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V SNF2_N PF00176.23 KXT05685.1 - 3.4e-60 203.6 0.4 6.4e-60 202.7 0.4 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXT05685.1 - 1.8e-16 60.5 0.0 5e-16 59.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXT05685.1 - 2.4e-09 37.4 0.9 2.7e-08 34.0 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HSA PF07529.13 KXT05685.1 - 0.0075 16.6 2.7 0.0075 16.6 2.7 3.6 2 1 1 3 3 3 1 HSA CTP_transf_1 PF01148.20 KXT05688.1 - 0.00027 20.8 2.6 0.00059 19.7 2.6 1.5 1 1 0 1 1 1 1 Cytidylyltransferase family DUF3984 PF13136.6 KXT05688.1 - 0.023 14.1 3.9 0.046 13.1 3.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3984) Fungal_trans PF04082.18 KXT05690.1 - 1.4e-16 60.3 0.1 3.1e-16 59.2 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT05690.1 - 1.4e-08 34.7 10.9 3e-08 33.7 10.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SpoU_methylase PF00588.19 KXT05691.1 - 3.2e-22 79.2 0.0 5.6e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 KXT05691.1 - 2.8e-11 43.5 0.0 6.6e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding GMC_oxred_C PF05199.13 KXT05692.1 - 4.4e-17 62.9 0.0 5.6e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase RasGAP PF00616.19 KXT05694.1 - 3.3e-31 108.6 0.1 6.5e-21 75.0 0.0 2.7 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 KXT05694.1 - 2.8e-05 24.3 0.0 0.00054 20.2 0.0 2.5 1 1 0 1 1 1 1 C2 domain PH_17 PF18012.1 KXT05694.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 PH domain Trehalase PF01204.18 KXT05696.1 - 1.4e-185 618.0 0.0 2.1e-185 617.4 0.0 1.2 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 KXT05696.1 - 1.6e-15 56.5 1.0 2.6e-15 55.8 1.0 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain SH3_1 PF00018.28 KXT05696.1 - 3.3e-14 52.2 0.0 6.3e-14 51.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXT05696.1 - 3.2e-10 39.7 0.0 6.5e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KXT05696.1 - 2.1e-07 30.5 0.0 5.4e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Nucleo_P87 PF07267.11 KXT05696.1 - 7.8 5.2 16.5 15 4.3 16.5 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 RRM_1 PF00076.22 KXT05697.1 - 2.1e-12 46.7 0.0 4.3e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lactamase_B_2 PF12706.7 KXT05697.1 - 5.3e-07 29.4 0.0 1.2e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DRMBL PF07522.14 KXT05697.1 - 0.00039 20.6 0.0 0.00085 19.5 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase RRM_7 PF16367.5 KXT05697.1 - 0.067 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif RMMBL PF07521.12 KXT05697.1 - 0.071 13.1 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain RRM_1 PF00076.22 KXT05698.1 - 2.1e-12 46.7 0.0 4.3e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lactamase_B_2 PF12706.7 KXT05698.1 - 5.5e-07 29.3 0.0 1.2e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DRMBL PF07522.14 KXT05698.1 - 0.00039 20.6 0.0 0.00085 19.5 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase RRM_7 PF16367.5 KXT05698.1 - 0.067 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif RMMBL PF07521.12 KXT05698.1 - 0.071 13.1 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain Sugar_tr PF00083.24 KXT05699.1 - 4.2e-84 283.0 21.7 4.8e-84 282.8 21.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXT05699.1 - 2.3e-14 53.1 32.0 2.3e-14 53.1 32.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Herpes_LMP1 PF05297.11 KXT05699.1 - 0.34 10.1 2.5 0.65 9.1 2.5 1.4 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Sugar_tr PF00083.24 KXT05700.1 - 4.2e-84 283.0 21.7 4.8e-84 282.8 21.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXT05700.1 - 2.3e-14 53.1 32.0 2.3e-14 53.1 32.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Herpes_LMP1 PF05297.11 KXT05700.1 - 0.34 10.1 2.5 0.65 9.1 2.5 1.4 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Sugar_tr PF00083.24 KXT05701.1 - 4.2e-84 283.0 21.7 4.8e-84 282.8 21.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXT05701.1 - 2.3e-14 53.1 32.0 2.3e-14 53.1 32.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Herpes_LMP1 PF05297.11 KXT05701.1 - 0.34 10.1 2.5 0.65 9.1 2.5 1.4 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) NDUF_B8 PF05821.11 KXT05704.1 - 6.6e-11 42.4 0.8 1e-10 41.7 0.8 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) DAO PF01266.24 KXT05705.1 - 0.013 15.1 0.0 0.015 14.9 0.0 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase 2OG-FeII_Oxy PF03171.20 KXT05706.1 - 5.6e-20 71.7 0.0 1.1e-19 70.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KXT05706.1 - 2.1e-10 41.3 0.0 3.6e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Methyltransf_33 PF10017.9 KXT05707.1 - 5.3e-63 213.0 0.1 4.5e-61 206.7 0.1 2.1 1 1 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent PTN13_u3 PF16599.5 KXT05707.1 - 0.023 14.7 0.1 0.31 11.1 0.1 2.2 2 0 0 2 2 2 0 Unstructured linker region on PTN13 protein between PDZ Pkinase PF00069.25 KXT05708.1 - 1.5e-63 214.6 0.0 2.1e-63 214.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT05708.1 - 4.7e-30 104.7 0.0 6.5e-29 101.0 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXT05708.1 - 0.0026 17.1 0.1 0.019 14.3 0.0 2.3 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.14 KXT05708.1 - 0.0036 16.7 0.0 0.0065 15.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KXT05708.1 - 0.0049 15.9 0.0 0.01 14.8 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KXT05708.1 - 0.0051 16.8 0.1 0.017 15.1 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family PH_3 PF14593.6 KXT05708.1 - 0.0062 16.6 0.0 0.014 15.5 0.0 1.6 1 0 0 1 1 1 1 PH domain Hydrolase PF00702.26 KXT05709.1 - 0.061 13.6 0.0 0.065 13.5 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase HTH_39 PF14090.6 KXT05709.1 - 0.14 11.9 0.0 0.34 10.7 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain Nucleopor_Nup85 PF07575.13 KXT05710.1 - 4.7e-26 91.5 3.4 6.5e-14 51.4 0.1 4.1 4 0 0 4 4 4 4 Nup85 Nucleoporin PBP1_TM PF14812.6 KXT05710.1 - 5.9 7.3 7.6 0.83 10.1 2.5 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GMC_oxred_N PF00732.19 KXT05711.1 - 5.8e-51 173.6 0.1 8.9e-51 173.0 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXT05711.1 - 7.4e-29 101.1 0.0 1.5e-28 100.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 KXT05711.1 - 0.00019 21.2 0.2 0.0014 18.3 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXT05711.1 - 0.00081 19.6 0.0 0.0025 18.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXT05711.1 - 0.0031 16.8 1.2 0.017 14.3 0.1 2.2 2 1 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 KXT05711.1 - 0.0056 15.8 0.1 0.19 10.8 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 KXT05711.1 - 0.0061 15.6 0.0 0.014 14.5 0.0 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KXT05711.1 - 0.055 12.7 0.2 1.2 8.3 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KXT05711.1 - 0.16 12.2 0.0 0.47 10.7 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain p450 PF00067.22 KXT05712.1 - 2.6e-52 178.1 0.0 9.9e-52 176.2 0.0 1.7 2 0 0 2 2 2 1 Cytochrome P450 Pkinase PF00069.25 KXT05713.1 - 3.1e-16 59.5 0.0 6.7e-12 45.3 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXT05713.1 - 5.5e-08 32.4 0.1 1.4e-07 31.1 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KXT05713.1 - 0.046 13.0 0.0 0.083 12.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF5056 PF16479.5 KXT05713.1 - 0.098 12.9 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5056) Pribosyl_synth PF14572.6 KXT05714.1 - 1.9e-34 119.3 0.3 1.1e-28 100.5 0.1 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 KXT05714.1 - 1.4e-33 115.3 0.0 2.9e-33 114.2 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 KXT05714.1 - 2.9e-15 56.2 0.1 1.5e-14 53.8 0.1 2.0 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KXT05714.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Pribosyl_synth PF14572.6 KXT05715.1 - 1.9e-34 119.3 0.3 1.1e-28 100.5 0.1 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 KXT05715.1 - 1.4e-33 115.3 0.0 2.9e-33 114.2 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 KXT05715.1 - 2.9e-15 56.2 0.1 1.5e-14 53.8 0.1 2.0 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KXT05715.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase NmrA PF05368.13 KXT05733.1 - 0.00015 21.4 0.0 0.00019 21.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXT05733.1 - 0.0015 18.5 0.0 0.0019 18.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Bac_rhodopsin PF01036.18 KXT05734.1 - 4e-14 52.7 1.5 4e-14 52.7 1.5 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Cmc1 PF08583.10 KXT05735.1 - 8.5e-08 32.1 2.7 8.5e-08 32.1 2.7 1.8 1 1 1 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like YqzE PF14038.6 KXT05735.1 - 9.3 6.3 8.5 6.1 6.9 6.4 1.8 1 1 1 2 2 2 0 YqzE-like protein Sds3 PF08598.11 KXT05736.1 - 1.2e-30 107.2 0.0 2.2e-30 106.3 0.0 1.6 1 1 0 1 1 1 1 Sds3-like OmpH PF03938.14 KXT05736.1 - 0.85 10.0 5.4 1 9.7 2.1 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF5595 PF18077.1 KXT05736.1 - 1.1 9.4 4.0 0.62 10.2 1.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF5595) DUF4201 PF13870.6 KXT05736.1 - 1.8 8.3 10.4 0.38 10.5 6.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) UQ_con PF00179.26 KXT05737.1 - 2.5e-44 150.3 0.0 3.1e-44 150.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KXT05737.1 - 0.0035 17.6 0.0 0.0035 17.6 0.0 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 KXT05737.1 - 0.072 12.8 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B Terpene_synth_C PF03936.16 KXT05738.1 - 0.019 14.3 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain Hydantoinase_B PF02538.14 KXT05739.1 - 1.2e-128 429.8 0.0 2.2e-128 428.9 0.0 1.4 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KXT05739.1 - 6.4e-91 304.6 2.5 6.4e-91 304.6 2.5 2.2 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KXT05739.1 - 1.3e-45 155.3 0.0 3.5e-43 147.4 0.0 2.7 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.6 KXT05739.1 - 6.1e-05 21.8 1.9 0.018 13.6 0.1 2.6 3 0 0 3 3 3 2 MutL protein BcrAD_BadFG PF01869.20 KXT05739.1 - 0.046 13.2 0.2 0.62 9.5 0.0 2.3 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Ppx-GppA PF02541.16 KXT05739.1 - 0.14 11.5 0.1 0.32 10.4 0.1 1.5 1 0 0 1 1 1 0 Ppx/GppA phosphatase family Plus-3 PF03126.18 KXT05740.1 - 3e-29 101.7 0.2 1.3e-28 99.7 0.0 2.1 2 0 0 2 2 2 1 Plus-3 domain hNIFK_binding PF12196.8 KXT05740.1 - 5.5 6.6 6.2 76 2.9 0.8 3.9 3 0 0 3 3 3 0 FHA Ki67 binding domain of hNIFK Ten1 PF12658.7 KXT05741.1 - 1.7e-29 102.2 0.0 2.2e-29 101.9 0.0 1.0 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Glyco_hydro_3 PF00933.21 KXT05742.1 - 2.3e-54 184.9 0.0 3.3e-54 184.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KXT05742.1 - 3.2e-53 180.7 0.0 5.2e-53 180.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KXT05742.1 - 7.2e-23 80.5 0.2 1.6e-22 79.4 0.2 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain CARDB PF07705.11 KXT05742.1 - 0.093 13.0 0.3 0.23 11.8 0.3 1.6 1 0 0 1 1 1 0 CARDB Herpes_gE PF02480.16 KXT05742.1 - 0.13 11.0 0.2 0.21 10.3 0.2 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF11 PF01345.18 KXT05742.1 - 0.16 12.3 1.6 0.77 10.1 1.6 2.1 1 1 0 1 1 1 0 Domain of unknown function DUF11 TMEM234 PF10639.9 KXT05743.1 - 1.2e-36 125.3 0.2 1.4e-36 125.0 0.2 1.1 1 0 0 1 1 1 1 Putative transmembrane family 234 EamA PF00892.20 KXT05743.1 - 0.00045 20.4 7.0 0.017 15.3 2.6 2.1 2 0 0 2 2 2 2 EamA-like transporter family TMEM234 PF10639.9 KXT05744.1 - 1.2e-36 125.3 0.2 1.4e-36 125.0 0.2 1.1 1 0 0 1 1 1 1 Putative transmembrane family 234 EamA PF00892.20 KXT05744.1 - 0.00045 20.4 7.0 0.017 15.3 2.6 2.1 2 0 0 2 2 2 2 EamA-like transporter family Laminin_II PF06009.12 KXT05745.1 - 0.027 14.5 0.1 0.14 12.1 0.0 2.3 1 1 1 2 2 2 0 Laminin Domain II BLOC1_2 PF10046.9 KXT05745.1 - 0.11 12.9 4.5 0.16 12.3 0.0 2.8 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2203 PF09969.9 KXT05745.1 - 0.11 13.2 5.0 0.071 13.8 1.3 2.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) PG_binding_1 PF01471.18 KXT05745.1 - 0.14 12.3 1.1 7.7 6.8 0.0 3.3 3 0 0 3 3 3 0 Putative peptidoglycan binding domain DUF1664 PF07889.12 KXT05745.1 - 0.16 12.0 1.6 3 7.9 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Taxilin PF09728.9 KXT05745.1 - 0.4 9.8 8.9 0.95 8.6 8.9 1.6 1 0 0 1 1 1 0 Myosin-like coiled-coil protein Spc7 PF08317.11 KXT05745.1 - 1.5 7.7 13.5 0.14 11.0 7.6 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF812 PF05667.11 KXT05745.1 - 7.9 5.2 22.7 0.0059 15.6 4.7 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF812) AMPK1_CBM PF16561.5 KXT05746.1 - 2.7e-20 72.4 2.8 5.3e-20 71.4 2.8 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Pkinase PF00069.25 KXT05749.1 - 5.9e-63 212.7 0.0 6.9e-62 209.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT05749.1 - 4.4e-28 98.3 0.0 2.1e-27 96.1 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KXT05749.1 - 0.0089 15.0 0.0 0.028 13.4 0.0 1.9 2 1 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 KXT05749.1 - 0.045 13.1 0.1 0.088 12.2 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KXT05749.1 - 0.053 13.4 0.0 0.17 11.8 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family BTB PF00651.31 KXT05750.1 - 1e-17 64.4 0.0 1.5e-07 31.6 0.0 2.6 2 1 0 2 2 2 2 BTB/POZ domain DUF2730 PF10805.8 KXT05750.1 - 0.18 11.9 0.0 0.96 9.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) UQ_con PF00179.26 KXT05751.1 - 1.5e-21 76.5 0.0 2.6e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme BUD22 PF09073.10 KXT05751.1 - 5.8 6.1 16.1 8.8 5.6 16.1 1.1 1 0 0 1 1 1 0 BUD22 ADH_N PF08240.12 KXT05752.1 - 1.7e-33 114.7 0.3 3.1e-33 113.9 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXT05752.1 - 2.7e-25 88.8 0.6 4.3e-25 88.2 0.6 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXT05752.1 - 8e-08 32.0 0.2 1.8e-07 30.9 0.2 1.6 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KXT05752.1 - 0.00056 21.0 0.0 0.0013 19.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KXT05752.1 - 0.00067 19.0 1.5 0.001 18.4 1.5 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 KXT05752.1 - 0.0041 16.7 0.1 0.0067 16.0 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_25 PF13649.6 KXT05752.1 - 0.0058 17.3 0.1 0.0098 16.6 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXT05752.1 - 0.032 13.8 0.1 0.058 12.9 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.6 KXT05752.1 - 0.068 13.0 0.0 0.16 11.8 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Glyco_hydro_28 PF00295.17 KXT05753.1 - 8.5e-118 393.1 16.7 1.1e-117 392.8 16.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DUF515 PF04415.12 KXT05753.1 - 0.38 9.1 11.7 0.66 8.3 11.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) TRAPP PF04051.16 KXT05755.1 - 3.8e-35 120.8 0.1 4.7e-35 120.5 0.1 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PNGaseA PF12222.8 KXT05755.1 - 0.018 13.9 0.0 0.021 13.7 0.0 1.1 1 0 0 1 1 1 0 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A GATase PF00117.28 KXT05757.1 - 8.4e-08 32.2 0.0 1.4e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Ig_J_chain PF15097.6 KXT05758.1 - 2.4 8.0 6.9 0.33 10.8 2.1 2.0 2 1 1 3 3 3 0 Immunoglobulin J chain FMN_dh PF01070.18 KXT05759.1 - 8.8e-87 291.4 0.2 1.8e-49 168.6 0.2 2.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.25 KXT05759.1 - 4.8e-05 22.5 0.0 0.00029 19.9 0.0 1.9 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KXT05759.1 - 0.00046 19.4 0.0 0.00072 18.8 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 KXT05759.1 - 0.018 14.5 0.2 0.16 11.4 0.1 2.2 2 0 0 2 2 2 0 Histidine biosynthesis protein NMO PF03060.15 KXT05759.1 - 0.031 13.6 0.1 0.051 13.0 0.1 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase PSP1 PF04468.12 KXT05760.1 - 3.5e-26 91.3 2.7 6.5e-26 90.4 2.7 1.5 1 0 0 1 1 1 1 PSP1 C-terminal conserved region AvrM_N PF18247.1 KXT05760.1 - 0.1 12.5 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Flax-rust effector AvrM N-terminal domain PSP1 PF04468.12 KXT05762.1 - 3.4e-26 91.3 2.7 6.4e-26 90.5 2.7 1.5 1 0 0 1 1 1 1 PSP1 C-terminal conserved region AvrM_N PF18247.1 KXT05762.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Flax-rust effector AvrM N-terminal domain NPV_P10 PF05531.12 KXT05763.1 - 0.036 14.5 0.6 0.071 13.6 0.6 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF1657 PF07870.11 KXT05763.1 - 0.07 13.0 0.1 0.18 11.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1657) HsbA PF12296.8 KXT05763.1 - 0.089 13.2 6.5 1.8 9.0 2.6 2.8 2 1 1 3 3 3 0 Hydrophobic surface binding protein A Presenilin PF01080.17 KXT05763.1 - 4.2 6.0 4.8 5.4 5.7 4.8 1.1 1 0 0 1 1 1 0 Presenilin ANAPC4_WD40 PF12894.7 KXT05764.1 - 2.2e-19 69.5 4.2 9.5e-07 29.0 0.1 4.6 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXT05764.1 - 2.2e-18 66.3 19.8 7.4e-05 23.4 0.1 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KXT05764.1 - 1.9e-07 30.4 0.1 0.00012 21.1 0.0 3.4 1 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 KXT05764.1 - 0.37 9.6 2.7 0.27 10.1 0.6 1.7 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain LMWPc PF01451.21 KXT05765.1 - 9.9e-31 107.0 0.0 1.6e-30 106.4 0.0 1.3 1 1 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Ost5 PF05251.12 KXT05766.1 - 1.8e-18 66.6 7.6 2.6e-18 66.1 7.6 1.3 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 MadM PF03818.13 KXT05766.1 - 0.039 13.8 0.9 0.051 13.4 0.9 1.3 1 1 0 1 1 1 0 Malonate/sodium symporter MadM subunit Chitin_synth_1 PF01644.17 KXT05767.1 - 1.8e-73 245.9 0.3 3.1e-73 245.1 0.3 1.4 1 0 0 1 1 1 1 Chitin synthase zf-CCHC PF00098.23 KXT05767.1 - 9.5e-43 142.4 120.8 1.5e-06 28.0 4.6 13.1 13 0 0 13 13 13 11 Zinc knuckle Chitin_synth_1N PF08407.11 KXT05767.1 - 2.1e-29 101.3 0.1 4.4e-29 100.3 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KXT05767.1 - 3.5e-21 75.4 3.3 1e-16 60.7 0.0 2.9 3 1 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KXT05767.1 - 1e-05 25.6 16.0 0.00011 22.2 16.0 2.4 1 1 0 1 1 1 1 Glycosyl transferase family group 2 zf-CCHC_2 PF13696.6 KXT05767.1 - 0.014 15.2 0.9 0.014 15.2 0.9 12.4 12 0 0 12 12 12 0 Zinc knuckle Glyco_tranf_2_3 PF13641.6 KXT05767.1 - 0.035 14.0 0.0 0.1 12.5 0.0 1.8 2 0 0 2 2 2 0 Glycosyltransferase like family 2 zf-CCHC_4 PF14392.6 KXT05767.1 - 0.3 10.8 80.5 0.22 11.3 0.8 12.3 11 1 1 12 12 12 0 Zinc knuckle zf-RING_2 PF13639.6 KXT05768.1 - 3.2e-05 24.2 9.7 9e-05 22.7 9.7 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KXT05768.1 - 6.5e-05 22.8 8.8 0.00013 21.8 8.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-UDP PF14569.6 KXT05768.1 - 0.071 13.2 3.5 0.17 12.0 3.5 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_11 PF17123.5 KXT05768.1 - 0.26 11.0 3.7 0.84 9.4 3.7 1.9 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_UBOX PF13445.6 KXT05768.1 - 0.35 10.9 9.9 1 9.4 9.9 1.9 1 0 0 1 1 1 0 RING-type zinc-finger Rhodanese_C PF12368.8 KXT05768.1 - 0.88 10.0 4.7 3.1 8.2 4.7 2.0 1 0 0 1 1 1 0 Rhodanase C-terminal Prok-RING_4 PF14447.6 KXT05768.1 - 1.4 8.9 8.8 4.1 7.3 8.8 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KXT05768.1 - 6.3 6.7 19.6 0.07 12.9 10.9 2.3 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain CAP59_mtransfer PF11735.8 KXT05769.1 - 0.057 13.1 0.0 0.065 12.9 0.0 1.1 1 0 0 1 1 1 0 Cryptococcal mannosyltransferase 1 SPATA3 PF15662.5 KXT05769.1 - 0.28 11.8 3.6 0.3 11.7 3.6 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family SIMPL PF04402.14 KXT05770.1 - 2e-26 93.7 0.0 2.3e-26 93.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) PilO PF04350.13 KXT05770.1 - 0.053 13.7 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Pilus assembly protein, PilO WD40 PF00400.32 KXT05771.1 - 1.8e-44 148.8 13.1 8.7e-08 32.7 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXT05771.1 - 2.9e-15 56.3 0.2 0.00039 20.7 0.0 5.0 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXT05771.1 - 0.00039 19.5 0.0 7.8 5.3 0.0 4.1 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KXT05771.1 - 0.028 13.0 0.0 0.057 11.9 0.0 1.5 1 0 0 1 1 1 0 Cytochrome D1 heme domain WD40 PF00400.32 KXT05772.1 - 1.8e-44 148.8 13.1 8.7e-08 32.7 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXT05772.1 - 2.9e-15 56.3 0.2 0.00039 20.7 0.0 5.0 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXT05772.1 - 0.00039 19.5 0.0 7.8 5.3 0.0 4.1 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KXT05772.1 - 0.028 13.0 0.0 0.057 11.9 0.0 1.5 1 0 0 1 1 1 0 Cytochrome D1 heme domain DUF155 PF02582.14 KXT05774.1 - 1.7e-54 184.6 0.0 3.7e-54 183.5 0.0 1.6 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 Beta-lactamase PF00144.24 KXT05774.1 - 1.2e-41 143.0 1.3 1.1e-40 139.9 0.3 2.6 2 1 0 2 2 2 1 Beta-lactamase Beta-lactamase2 PF13354.6 KXT05774.1 - 0.037 13.6 0.0 0.083 12.5 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase enzyme family IlvN PF07991.12 KXT05775.1 - 7.2e-47 159.0 0.0 1.1e-46 158.4 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 KXT05775.1 - 4.4e-41 140.5 0.2 1.1e-40 139.3 0.2 1.7 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.17 KXT05775.1 - 0.026 15.1 0.0 0.087 13.4 0.0 1.9 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GWT1 PF06423.12 KXT05776.1 - 4.8e-43 146.8 0.0 1.7e-42 145.0 0.0 2.0 2 0 0 2 2 2 1 GWT1 NPCC PF08058.11 KXT05776.1 - 0.15 12.1 0.1 0.35 10.9 0.1 1.5 1 0 0 1 1 1 0 Nuclear pore complex component Dor1 PF04124.12 KXT05777.1 - 7.4e-52 176.1 3.6 4.5e-38 130.8 3.0 2.2 2 0 0 2 2 2 2 Dor1-like family zf-C2H2 PF00096.26 KXT05778.1 - 1.2e-09 38.1 16.3 0.00023 21.4 0.5 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXT05778.1 - 1.5e-07 31.7 11.9 0.0065 17.2 0.3 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Di19 PF05605.12 KXT05778.1 - 0.006 16.8 9.8 0.008 16.4 0.7 2.4 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_12 PF18658.1 KXT05778.1 - 0.044 13.4 1.0 0.1 12.2 0.2 2.0 2 0 0 2 2 2 0 Zinc-finger C2H2-type zf-H2C2_2 PF13465.6 KXT05778.1 - 0.12 12.8 10.1 0.99 9.9 0.6 3.8 3 0 0 3 3 3 0 Zinc-finger double domain FOXP-CC PF16159.5 KXT05778.1 - 1.4 9.6 5.4 1.9 9.2 0.8 3.0 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 KXT05778.1 - 1.9 8.6 6.3 36 4.5 0.0 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Aldedh PF00171.22 KXT05779.1 - 1.5e-74 251.2 0.0 1.9e-74 250.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AMP-binding PF00501.28 KXT05780.1 - 1.7e-66 224.6 0.0 2.3e-66 224.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.20 KXT05780.1 - 9.2e-19 68.5 0.0 2.1e-18 67.3 0.0 1.7 1 1 0 1 1 1 1 Thioesterase domain PP-binding PF00550.25 KXT05780.1 - 2.9e-05 24.3 0.0 6.5e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_1 PF00561.20 KXT05780.1 - 0.001 18.8 0.0 0.0038 16.9 0.0 1.9 2 1 0 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 KXT05780.1 - 0.0083 15.7 0.1 0.026 14.1 0.0 1.7 2 0 0 2 2 2 1 Dienelactone hydrolase family COQ7 PF03232.13 KXT05782.1 - 6.8e-62 208.3 0.0 1.2e-61 207.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 KXT05782.1 - 0.00017 22.0 0.1 0.00091 19.6 0.0 2.2 1 1 0 2 2 2 1 Rubrerythrin Ala_racemase_N PF01168.20 KXT05782.1 - 0.073 12.7 0.3 1.1 8.8 0.0 2.5 2 1 1 3 3 3 0 Alanine racemase, N-terminal domain Crr6 PF08847.11 KXT05782.1 - 0.09 12.4 0.4 1 9.0 0.0 2.5 2 1 1 3 3 3 0 Chlororespiratory reduction 6 UPF0184 PF03670.13 KXT05782.1 - 0.58 10.6 2.1 2.1 8.8 2.1 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0184) COQ7 PF03232.13 KXT05785.1 - 6.8e-62 208.3 0.0 1.2e-61 207.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 KXT05785.1 - 0.00017 22.0 0.1 0.00091 19.6 0.0 2.2 1 1 0 2 2 2 1 Rubrerythrin Ala_racemase_N PF01168.20 KXT05785.1 - 0.073 12.7 0.3 1.1 8.8 0.0 2.5 2 1 1 3 3 3 0 Alanine racemase, N-terminal domain Crr6 PF08847.11 KXT05785.1 - 0.09 12.4 0.4 1 9.0 0.0 2.5 2 1 1 3 3 3 0 Chlororespiratory reduction 6 UPF0184 PF03670.13 KXT05785.1 - 0.58 10.6 2.1 2.1 8.8 2.1 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0184) COQ7 PF03232.13 KXT05787.1 - 6.8e-62 208.3 0.0 1.2e-61 207.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 KXT05787.1 - 0.00017 22.0 0.1 0.00091 19.6 0.0 2.2 1 1 0 2 2 2 1 Rubrerythrin Ala_racemase_N PF01168.20 KXT05787.1 - 0.073 12.7 0.3 1.1 8.8 0.0 2.5 2 1 1 3 3 3 0 Alanine racemase, N-terminal domain Crr6 PF08847.11 KXT05787.1 - 0.09 12.4 0.4 1 9.0 0.0 2.5 2 1 1 3 3 3 0 Chlororespiratory reduction 6 UPF0184 PF03670.13 KXT05787.1 - 0.58 10.6 2.1 2.1 8.8 2.1 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0184) MFS_1 PF07690.16 KXT05788.1 - 4e-34 118.1 34.9 1.1e-33 116.6 34.9 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily PAP_PilO PF06864.12 KXT05788.1 - 0.099 11.4 0.1 0.16 10.8 0.1 1.2 1 0 0 1 1 1 0 Pilin accessory protein (PilO) MFS_1_like PF12832.7 KXT05788.1 - 0.24 10.2 17.2 1.4 7.7 16.3 2.5 1 1 0 1 1 1 0 MFS_1 like family DUF2681 PF10883.8 KXT05788.1 - 0.44 11.0 1.8 0.76 10.2 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) DUF3188 PF11384.8 KXT05788.1 - 0.48 10.2 2.7 1.2 8.9 1.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) Snf7 PF03357.21 KXT05789.1 - 8.9e-34 116.6 25.3 8.9e-34 116.6 25.3 2.0 1 1 1 2 2 2 2 Snf7 MFS_1 PF07690.16 KXT05790.1 - 1.3e-41 142.7 44.0 1.3e-41 142.7 44.0 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily PAP_PilO PF06864.12 KXT05790.1 - 0.14 11.0 0.1 0.23 10.2 0.1 1.3 1 0 0 1 1 1 0 Pilin accessory protein (PilO) DUF2681 PF10883.8 KXT05790.1 - 0.46 10.9 1.3 1.1 9.7 0.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) Fungal_trans PF04082.18 KXT05791.1 - 6.6e-13 48.3 1.1 1.7e-12 46.9 1.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 KXT05791.1 - 5.1e-07 29.8 7.9 0.00022 21.5 3.1 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KXT05791.1 - 5.6e-07 29.7 7.9 0.0078 16.6 1.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXT05791.1 - 5.3e-06 26.8 6.9 0.013 16.2 1.2 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXT05791.1 - 8.6e-06 25.9 3.9 0.017 15.4 0.5 3.1 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding Zn_clus PF00172.18 KXT05791.1 - 0.002 18.2 8.0 0.002 18.2 8.0 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 KXT05793.1 - 8.1e-110 367.8 29.4 1e-109 367.4 29.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXT05793.1 - 8.4e-17 61.1 35.1 2.6e-13 49.6 10.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Pyr_redox_2 PF07992.14 KXT05795.1 - 6.7e-08 32.1 0.0 3.5e-05 23.2 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXT05795.1 - 2.6e-07 30.7 0.1 0.0015 18.5 0.0 3.6 3 1 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KXT05795.1 - 4.1e-07 30.1 0.0 5.4e-06 26.5 0.0 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KXT05795.1 - 1.1e-05 24.8 0.0 0.0011 18.2 0.1 3.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KXT05795.1 - 1.6e-05 23.6 0.0 0.00011 20.8 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KXT05795.1 - 3.3e-05 23.2 0.0 0.019 14.1 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) ThiF PF00899.21 KXT05795.1 - 0.00057 19.3 0.2 0.12 11.7 0.1 2.2 2 0 0 2 2 2 2 ThiF family Shikimate_DH PF01488.20 KXT05795.1 - 0.0032 17.5 0.1 0.2 11.7 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 KXT05795.1 - 0.012 15.2 1.0 0.97 8.9 0.5 2.9 2 1 1 3 3 3 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 KXT05795.1 - 0.062 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MFS_1 PF07690.16 KXT05796.1 - 2.3e-29 102.4 60.0 6.1e-26 91.2 49.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily APH PF01636.23 KXT05796.1 - 6.9e-11 42.5 0.1 1.6e-10 41.3 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Sugar_tr PF00083.24 KXT05796.1 - 8.3e-06 24.9 42.4 0.00045 19.2 15.9 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 KXT05796.1 - 7e-05 21.9 6.1 7e-05 21.9 6.1 2.2 2 0 0 2 2 2 2 MFS_1 like family Ribonuc_L-PSP PF01042.21 KXT05797.1 - 9.6e-36 122.5 0.0 1.4e-35 122.0 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP Bromodomain PF00439.25 KXT05798.1 - 3.6e-23 81.4 0.1 7.2e-23 80.5 0.1 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 KXT05798.1 - 1.4e-08 35.0 0.0 2.7e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family GST_N_2 PF13409.6 KXT05798.1 - 1.8e-07 31.3 0.0 5.4e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXT05798.1 - 1e-06 28.7 0.3 2.6e-06 27.3 0.3 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KXT05798.1 - 1.1e-06 28.9 0.1 4.5e-06 27.0 0.1 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Acetyltransf_10 PF13673.7 KXT05798.1 - 1.2e-06 28.5 0.2 3.1e-06 27.1 0.2 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXT05798.1 - 5.4e-05 23.5 0.1 0.00014 22.2 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AT_hook PF02178.19 KXT05798.1 - 0.032 14.1 0.8 0.15 12.0 0.8 2.3 1 0 0 1 1 1 0 AT hook motif Sugar_tr PF00083.24 KXT05799.1 - 9.6e-72 242.3 20.0 1.1e-71 242.1 20.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXT05799.1 - 2.5e-27 95.7 22.6 2.5e-27 95.7 22.6 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily KbaA PF14089.6 KXT05799.1 - 0.009 15.9 4.0 0.023 14.5 4.0 1.6 1 0 0 1 1 1 1 KinB-signalling pathway activation in sporulation adh_short_C2 PF13561.6 KXT05800.1 - 1.1e-50 172.4 2.7 2.9e-50 171.0 2.7 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXT05800.1 - 1.8e-43 148.3 1.9 2.8e-43 147.6 1.9 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXT05800.1 - 3.5e-11 43.3 2.0 7e-11 42.4 1.9 1.5 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 KXT05800.1 - 0.015 14.3 1.3 0.048 12.7 1.2 1.8 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family C2 PF00168.30 KXT05801.1 - 4.1e-78 258.3 1.3 5.4e-19 68.4 0.0 5.7 6 0 0 6 6 6 5 C2 domain MLVIN_C PF18697.1 KXT05801.1 - 0.06 13.4 0.2 2 8.6 0.0 3.3 3 0 0 3 3 3 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain Cupin_8 PF13621.6 KXT05802.1 - 2.4e-38 132.3 0.0 3.2e-38 131.9 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KXT05802.1 - 1.2e-06 28.2 0.0 0.0019 17.7 0.0 2.3 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.22 KXT05802.1 - 0.076 13.5 0.4 0.69 10.4 0.1 2.5 3 0 0 3 3 3 0 JmjC domain, hydroxylase Adenine_deam_C PF13382.6 KXT05802.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Adenine deaminase C-terminal domain Cupin_8 PF13621.6 KXT05803.1 - 2.4e-38 132.3 0.0 3.2e-38 131.9 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KXT05803.1 - 1.2e-06 28.2 0.0 0.0019 17.7 0.0 2.3 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.22 KXT05803.1 - 0.076 13.5 0.4 0.69 10.4 0.1 2.5 3 0 0 3 3 3 0 JmjC domain, hydroxylase Adenine_deam_C PF13382.6 KXT05803.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Adenine deaminase C-terminal domain ER_lumen_recept PF00810.18 KXT05804.1 - 9.9e-44 149.7 13.3 1.7e-43 148.9 13.3 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 KXT05804.1 - 0.00084 19.1 7.0 0.0096 15.7 0.3 3.3 3 0 0 3 3 3 2 PQ loop repeat NfeD PF01957.18 KXT05804.1 - 0.21 12.0 0.4 1.3 9.5 0.0 2.2 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding ILVD_EDD PF00920.21 KXT05805.1 - 1.5e-212 706.8 2.5 1.8e-212 706.6 2.5 1.0 1 0 0 1 1 1 1 Dehydratase family Sipho_tail PF05709.11 KXT05805.1 - 0.19 11.1 0.0 0.57 9.5 0.0 1.4 1 1 0 1 1 1 0 Phage tail protein GPI-anchored PF10342.9 KXT05806.1 - 1.3e-21 77.1 0.8 1.3e-21 77.1 0.8 2.3 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Cellulase PF00150.18 KXT05806.1 - 1.2e-11 44.6 6.1 1.5e-10 41.0 6.1 2.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Recep_L_domain PF01030.24 KXT05806.1 - 0.0001 22.4 2.9 0.38 10.9 0.1 3.4 1 1 1 2 2 2 2 Receptor L domain SKG6 PF08693.10 KXT05806.1 - 0.00022 20.6 0.1 0.00047 19.5 0.1 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain FAM176 PF14851.6 KXT05806.1 - 0.44 10.2 1.4 4.8 6.8 0.0 2.3 2 0 0 2 2 2 0 FAM176 family LRR_4 PF12799.7 KXT05806.1 - 0.73 10.3 6.6 0.23 11.9 0.3 3.3 2 2 1 3 3 3 0 Leucine Rich repeats (2 copies) MRP-S28 PF10213.9 KXT05807.1 - 6.9e-37 126.7 2.2 1.1e-36 126.0 2.2 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein Med1 PF10744.9 KXT05808.1 - 7e-76 255.9 0.0 9.3e-76 255.5 0.0 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 BTB PF00651.31 KXT05809.1 - 0.029 14.6 0.0 0.43 10.8 0.0 2.2 2 0 0 2 2 2 0 BTB/POZ domain Glyco_hydro_127 PF07944.12 KXT05810.1 - 9.1e-118 394.0 0.0 1.1e-117 393.8 0.0 1.0 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 PTR2 PF00854.21 KXT05811.1 - 2.9e-57 194.3 9.0 3.9e-57 193.9 9.0 1.2 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 KXT05811.1 - 9.1e-07 28.1 27.9 9.1e-07 28.1 27.9 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily CcmH PF03918.14 KXT05811.1 - 0.48 9.7 2.6 1.2 8.4 0.0 2.5 3 0 0 3 3 3 0 Cytochrome C biogenesis protein Kelch_4 PF13418.6 KXT05812.1 - 7.3e-24 83.5 8.6 2e-07 30.9 0.0 5.5 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KXT05812.1 - 1.4e-21 76.0 7.8 3.5e-06 26.9 0.0 5.0 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 KXT05812.1 - 9.3e-21 73.4 5.1 1.9e-05 24.8 0.2 5.9 3 1 2 5 5 5 4 Kelch motif Kelch_1 PF01344.25 KXT05812.1 - 1.5e-18 66.1 2.8 9.1e-06 25.2 0.1 5.1 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 KXT05812.1 - 7.6e-17 60.6 7.0 7.5e-06 25.7 0.3 5.4 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 KXT05812.1 - 1e-14 54.4 11.4 1.7e-05 25.0 0.0 6.5 7 0 0 7 7 7 2 Galactose oxidase, central domain BTB PF00651.31 KXT05812.1 - 1.8e-10 41.0 0.0 3.2e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Nsp1_C PF05064.13 KXT05813.1 - 4e-30 104.0 0.0 8e-30 103.0 0.0 1.5 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 KXT05813.1 - 1.2e-12 48.5 217.6 0.00044 21.0 36.0 8.8 1 1 6 7 7 5 4 Nucleoporin FG repeat region ATG16 PF08614.11 KXT05813.1 - 3.3e-06 27.5 5.1 6.6e-05 23.2 0.1 2.9 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) GAS PF13851.6 KXT05813.1 - 0.0066 15.8 1.4 0.11 11.8 0.0 2.1 1 1 0 2 2 2 1 Growth-arrest specific micro-tubule binding AAA_13 PF13166.6 KXT05813.1 - 0.023 13.3 1.4 0.034 12.8 1.4 1.1 1 0 0 1 1 1 0 AAA domain Lip_prot_lig_C PF10437.9 KXT05813.1 - 0.024 14.6 0.0 0.052 13.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial lipoate protein ligase C-terminus DUF3450 PF11932.8 KXT05813.1 - 0.052 12.8 0.2 0.052 12.8 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) FlaC_arch PF05377.11 KXT05813.1 - 0.067 13.6 2.7 0.53 10.7 0.1 2.6 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) MscS_porin PF12795.7 KXT05813.1 - 0.14 11.7 9.6 0.94 9.0 0.5 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain OmpH PF03938.14 KXT05813.1 - 0.22 11.9 1.4 0.6 10.4 0.1 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) CENP-Q PF13094.6 KXT05813.1 - 0.23 11.6 2.1 1.3 9.2 2.1 2.0 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit APG6_N PF17675.1 KXT05813.1 - 0.24 11.9 5.4 6.8 7.2 0.6 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region Phage_GP20 PF06810.11 KXT05813.1 - 0.45 10.3 3.7 0.29 10.9 0.5 2.0 2 0 0 2 2 2 0 Phage minor structural protein GP20 TolA_bind_tri PF16331.5 KXT05813.1 - 0.84 9.8 4.0 2.2 8.4 0.1 2.4 2 0 0 2 2 2 0 TolA binding protein trimerisation HMMR_N PF15905.5 KXT05813.1 - 0.96 8.8 3.8 0.56 9.6 1.3 1.7 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF16 PF01519.16 KXT05813.1 - 1.4 9.5 3.4 11 6.6 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 Sec34 PF04136.15 KXT05813.1 - 1.4 8.8 3.3 5.2 6.9 0.7 2.2 2 0 0 2 2 2 0 Sec34-like family Tropomyosin_1 PF12718.7 KXT05813.1 - 2.2 8.4 7.1 0.26 11.4 2.2 1.8 2 0 0 2 2 2 0 Tropomyosin like ADIP PF11559.8 KXT05813.1 - 2.9 7.9 10.0 0.84 9.7 1.1 2.7 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Prominin PF05478.11 KXT05813.1 - 3.2 5.6 4.2 8.9 4.1 0.2 2.0 2 0 0 2 2 2 0 Prominin DUF1664 PF07889.12 KXT05813.1 - 3.4 7.7 5.0 4.6 7.3 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 KXT05813.1 - 3.9 6.3 7.9 1.5 7.7 2.0 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein IFT57 PF10498.9 KXT05813.1 - 4.5 6.1 6.4 5.8 5.8 1.2 2.0 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Prefoldin_2 PF01920.20 KXT05813.1 - 9.9 6.2 7.9 1.1 9.3 0.3 2.7 2 1 0 3 3 3 0 Prefoldin subunit tRNA-synt_1 PF00133.22 KXT05814.1 - 1.5e-199 664.2 0.0 9.3e-199 661.6 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KXT05814.1 - 4.1e-23 82.0 0.0 3e-21 76.0 0.0 2.8 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KXT05814.1 - 1.7e-15 56.7 0.0 2.4e-05 23.3 0.0 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KXT05814.1 - 0.029 13.7 0.0 0.078 12.3 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain AMP-binding PF00501.28 KXT05815.1 - 3.1e-66 223.7 0.0 3.9e-66 223.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXT05815.1 - 1.7e-07 32.1 0.0 4.2e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain F-box PF00646.33 KXT05816.1 - 0.053 13.4 0.4 0.14 12.1 0.4 1.7 1 1 0 1 1 1 0 F-box domain F-box-like_2 PF13013.6 KXT05816.1 - 0.064 13.2 0.1 0.2 11.7 0.1 1.8 1 1 0 1 1 1 0 F-box-like domain Gln-synt_C PF00120.24 KXT05817.1 - 5e-17 61.9 0.0 1.8e-14 53.5 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KXT05817.1 - 1.5e-10 40.7 0.0 2.8e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Opy2 PF09463.10 KXT05820.1 - 2.6e-09 37.2 20.6 4.2e-09 36.6 20.6 1.3 1 0 0 1 1 1 1 Opy2 protein MAP17 PF15807.5 KXT05820.1 - 0.0069 16.6 0.1 0.014 15.6 0.1 1.5 1 0 0 1 1 1 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 ABC_tran_Xtn PF12848.7 KXT05820.1 - 0.5 10.4 2.9 0.91 9.6 2.9 1.4 1 0 0 1 1 1 0 ABC transporter PhyH PF05721.13 KXT05821.1 - 3.4e-56 190.9 0.0 4e-56 190.6 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Apt1 PF10351.9 KXT05822.1 - 4.6 6.0 10.3 6.6 5.5 10.3 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 KXT05822.1 - 4.7 5.6 7.4 5.4 5.4 7.4 1.1 1 0 0 1 1 1 0 Macoilin family Amidase PF01425.21 KXT05823.1 - 1.2e-75 255.2 0.5 1.8e-52 178.8 0.0 2.2 2 0 0 2 2 2 2 Amidase PspB PF06667.12 KXT05824.1 - 0.092 12.8 1.6 0.19 11.8 1.6 1.5 1 0 0 1 1 1 0 Phage shock protein B DUF4407 PF14362.6 KXT05824.1 - 4.1 6.7 10.4 5.2 6.3 10.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) XhlA PF10779.9 KXT05824.1 - 4.9 7.4 11.7 0.98 9.7 6.6 2.1 2 0 0 2 2 2 0 Haemolysin XhlA PLDc PF00614.22 KXT05825.1 - 3.1e-14 52.5 0.4 1e-06 28.6 0.2 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 KXT05825.1 - 1.3e-11 44.5 0.0 3.1e-06 27.1 0.0 2.8 2 0 0 2 2 2 2 PLD-like domain PX PF00787.24 KXT05825.1 - 3.1e-10 40.0 0.7 1.2e-09 38.1 0.0 2.4 3 0 0 3 3 3 1 PX domain Transferase PF02458.15 KXT05826.1 - 5.3e-23 81.4 0.2 6.3e-22 77.8 0.2 2.4 1 1 0 1 1 1 1 Transferase family MFS_1 PF07690.16 KXT05827.1 - 0.00011 21.3 4.0 0.00011 21.3 4.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily cNMP_binding PF00027.29 KXT05828.1 - 1.9e-39 133.6 0.0 2.5e-18 65.9 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 KXT05828.1 - 2.3e-10 39.9 0.1 4.7e-10 39.0 0.1 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit YscJ_FliF PF01514.17 KXT05828.1 - 0.14 11.8 0.0 9 5.9 0.0 2.2 2 0 0 2 2 2 0 Secretory protein of YscJ/FliF family PCI PF01399.27 KXT05829.1 - 0.00013 22.5 0.0 0.00019 21.9 0.0 1.3 1 0 0 1 1 1 1 PCI domain CSN7a_helixI PF18392.1 KXT05829.1 - 0.065 13.2 0.2 0.16 11.9 0.2 1.6 1 0 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain DUF4611 PF15387.6 KXT05829.1 - 0.68 10.2 5.6 7.1 6.9 2.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Wtap PF17098.5 KXT05830.1 - 0.081 12.8 0.2 0.21 11.5 0.2 1.6 1 0 0 1 1 1 0 WTAP/Mum2p family TPR_1 PF00515.28 KXT05831.1 - 1.3e-41 138.7 25.8 1.1e-05 25.0 0.1 9.8 9 0 0 9 9 9 8 Tetratricopeptide repeat STI1 PF17830.1 KXT05831.1 - 4.4e-35 119.4 13.4 6.4e-20 70.8 0.9 2.9 2 0 0 2 2 2 2 STI1 domain TPR_2 PF07719.17 KXT05831.1 - 1.2e-31 106.2 30.5 0.00019 21.3 0.7 10.0 10 0 0 10 10 9 9 Tetratricopeptide repeat TPR_11 PF13414.6 KXT05831.1 - 3.6e-18 65.0 19.8 0.00031 20.4 0.1 8.1 6 2 2 8 8 8 5 TPR repeat TPR_8 PF13181.6 KXT05831.1 - 4.6e-18 63.9 27.0 3e-05 23.9 0.2 9.6 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_19 PF14559.6 KXT05831.1 - 1.9e-17 63.5 16.1 0.0027 18.2 0.3 7.2 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.6 KXT05831.1 - 5.7e-17 62.1 11.2 0.013 16.1 0.2 6.1 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.6 KXT05831.1 - 1.2e-13 50.4 7.6 0.026 14.9 0.2 7.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 KXT05831.1 - 1e-12 47.8 22.4 0.032 15.0 0.6 9.1 7 3 2 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 KXT05831.1 - 3.7e-12 46.4 20.5 1.2e-09 38.3 0.2 6.6 4 4 2 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 KXT05831.1 - 1.9e-10 40.7 8.9 0.00018 21.6 0.1 5.1 4 3 1 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KXT05831.1 - 2e-08 33.7 5.6 0.00014 21.6 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 KXT05831.1 - 1.4e-05 25.4 21.5 0.89 10.3 0.1 8.7 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_10 PF13374.6 KXT05831.1 - 0.00015 21.5 10.4 1.4 8.9 0.0 6.2 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_20 PF14561.6 KXT05831.1 - 0.014 15.7 0.1 0.014 15.7 0.1 5.8 6 1 1 7 7 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KXT05831.1 - 0.026 14.7 11.3 0.2 11.9 1.0 4.0 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Trypan_PARP PF05887.11 KXT05831.1 - 0.04 13.9 11.2 0.14 12.1 11.2 1.9 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) ProQ PF04352.13 KXT05831.1 - 0.097 12.6 8.5 0.41 10.6 3.4 2.9 2 0 0 2 2 2 0 ProQ/FINO family Fis1_TPR_C PF14853.6 KXT05831.1 - 0.15 12.2 15.7 0.16 12.1 0.0 5.6 8 0 0 8 8 5 0 Fis1 C-terminal tetratricopeptide repeat RPN7 PF10602.9 KXT05831.1 - 0.34 10.6 7.0 3.4 7.3 0.0 4.6 4 2 2 6 6 6 0 26S proteasome subunit RPN7 DUF5486 PF17588.2 KXT05831.1 - 0.46 10.4 3.4 1.1 9.1 2.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5486) Alkyl_sulf_dimr PF14863.6 KXT05831.1 - 0.5 10.8 12.1 57 4.2 0.1 4.7 4 1 1 5 5 5 0 Alkyl sulfatase dimerisation TPR_3 PF07720.12 KXT05831.1 - 5.8 7.0 11.4 55 3.9 0.0 6.0 6 1 1 7 7 6 0 Tetratricopeptide repeat TOM20_plant PF06552.12 KXT05831.1 - 6.7 6.4 9.1 3.9 7.2 0.1 4.0 5 0 0 5 5 5 0 Plant specific mitochondrial import receptor subunit TOM20 Glyco_hydro_3_C PF01915.22 KXT05832.1 - 1.7e-47 162.0 0.0 2.6e-47 161.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXT05832.1 - 5.2e-32 111.5 0.0 1.2e-31 110.3 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXT05832.1 - 2.6e-22 78.7 0.0 5e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Esterase_phd PF10503.9 KXT05833.1 - 4e-10 39.5 0.1 8.9e-05 22.1 0.0 2.9 2 1 0 2 2 2 2 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KXT05833.1 - 3.7e-05 23.3 0.0 5.9e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KXT05833.1 - 0.061 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Pkinase PF00069.25 KXT05834.1 - 0.00021 20.7 0.0 0.002 17.5 0.0 2.5 1 1 0 1 1 1 1 Protein kinase domain DUF4448 PF14610.6 KXT05836.1 - 0.0031 17.3 0.1 0.0063 16.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DB_JBP1 PF18526.1 KXT05836.1 - 0.045 13.7 1.6 0.049 13.6 0.2 1.7 2 0 0 2 2 2 0 Thymine dioxygenase JBP1 DNA-binding domain Alpha-amylase PF00128.24 KXT05837.1 - 2.2e-58 198.4 0.2 3.1e-58 197.9 0.2 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain CBM_20 PF00686.19 KXT05837.1 - 7.2e-31 106.0 1.8 1.2e-30 105.3 0.9 1.9 2 0 0 2 2 2 1 Starch binding domain DUF1966 PF09260.11 KXT05837.1 - 2.9e-16 59.5 0.3 8.6e-16 58.0 0.3 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) PAN_4 PF14295.6 KXT05837.1 - 0.69 9.9 4.7 0.14 12.1 0.6 2.0 2 0 0 2 2 2 0 PAN domain F-box PF00646.33 KXT05838.1 - 0.013 15.4 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 F-box domain F-box-like_2 PF13013.6 KXT05838.1 - 0.043 13.8 0.2 0.12 12.3 0.2 1.7 1 1 0 1 1 1 0 F-box-like domain RVT_connect PF06815.13 KXT05838.1 - 0.12 12.6 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase connection domain MFS_1 PF07690.16 KXT05839.1 - 3.5e-28 98.5 31.0 3.5e-28 98.5 31.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2070 PF09843.9 KXT05839.1 - 1.4 7.1 14.0 0.021 13.2 2.3 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) ApbA_C PF08546.11 KXT05840.1 - 1.8e-28 99.3 0.0 3.2e-28 98.4 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KXT05840.1 - 1.5e-23 83.1 0.0 2.2e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Aldedh PF00171.22 KXT05843.1 - 6e-147 489.9 0.0 7.4e-147 489.6 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family T3SchapCesA PF11439.8 KXT05843.1 - 0.14 12.3 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 Type III secretion system filament chaperone CesA AAA_12 PF13087.6 KXT05844.1 - 9.3e-33 113.5 0.0 1.7e-32 112.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KXT05844.1 - 5.4e-25 88.7 0.1 1.4e-15 57.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KXT05844.1 - 7.6e-11 42.5 0.0 2.4e-10 40.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KXT05844.1 - 5.8e-09 35.9 0.0 9.6e-08 32.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KXT05844.1 - 2.9e-05 23.9 0.0 1.7 8.4 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 KXT05844.1 - 4.3e-05 23.2 0.0 0.00041 20.0 0.0 2.1 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain ResIII PF04851.15 KXT05844.1 - 5e-05 23.4 0.0 7.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 KXT05844.1 - 0.00035 20.5 0.0 0.0013 18.6 0.0 2.1 2 1 0 2 2 2 1 Helicase AAA_22 PF13401.6 KXT05844.1 - 0.00098 19.4 0.0 0.0032 17.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KXT05844.1 - 0.0011 18.1 0.0 0.0021 17.2 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.6 KXT05844.1 - 0.0044 17.4 0.0 0.017 15.5 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.9 KXT05844.1 - 0.0051 16.1 0.0 0.057 12.7 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 KXT05844.1 - 0.0056 16.2 0.0 0.014 14.8 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein AAA PF00004.29 KXT05844.1 - 0.018 15.5 0.0 0.088 13.2 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KXT05844.1 - 0.02 14.8 0.0 4.1 7.3 0.1 2.3 1 1 1 2 2 2 0 Rad17 P-loop domain DEAD PF00270.29 KXT05844.1 - 0.051 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase UvrD_C_2 PF13538.6 KXT05844.1 - 0.17 11.8 0.0 0.51 10.2 0.0 1.8 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_7 PF12775.7 KXT05844.1 - 0.2 11.1 0.0 0.39 10.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Glyco_tran_28_C PF04101.16 KXT05846.1 - 9.1e-18 64.8 0.0 1.2e-17 64.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain ADH_N PF08240.12 KXT05847.1 - 2.9e-26 91.5 1.3 5.8e-26 90.5 1.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXT05847.1 - 1.9e-09 37.6 0.3 6.8e-06 26.1 0.0 2.8 3 0 0 3 3 3 2 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 KXT05847.1 - 0.00092 19.1 1.9 0.00092 19.1 1.9 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated FAD_binding_3 PF01494.19 KXT05847.1 - 0.16 11.2 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_6 PF08030.12 KXT05848.1 - 1e-15 58.2 0.0 1.7e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KXT05848.1 - 6e-12 45.6 0.0 1.1e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 KXT05848.1 - 1.4e-08 34.9 10.2 1.4e-08 34.9 10.2 3.0 2 2 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 KXT05848.1 - 0.03 15.0 0.0 1.5 9.5 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain PDR_assoc PF08370.11 KXT05848.1 - 0.4 10.4 5.7 0.066 13.0 0.9 2.2 2 0 0 2 2 2 0 Plant PDR ABC transporter associated SSF PF00474.17 KXT05849.1 - 5.7e-17 61.7 25.8 8.6e-17 61.1 25.8 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family DUF1992 PF09350.10 KXT05849.1 - 0.012 15.8 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1992) CoA_binding_3 PF13727.6 KXT05849.1 - 0.012 15.6 3.2 0.047 13.7 0.0 2.7 2 0 0 2 2 2 0 CoA-binding domain Pkinase PF00069.25 KXT05850.1 - 1.7e-11 44.0 0.0 2.4e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT05850.1 - 2.5e-09 36.8 0.0 3.7e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase ABC_membrane_2 PF06472.15 KXT05851.1 - 1.1e-89 300.4 0.0 1.8e-89 299.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KXT05851.1 - 2.9e-15 57.0 0.0 8.9e-15 55.4 0.0 1.8 2 0 0 2 2 2 1 ABC transporter THOC7 PF05615.13 KXT05851.1 - 9.3e-05 22.7 0.3 0.00025 21.3 0.3 1.6 1 0 0 1 1 1 1 Tho complex subunit 7 AAA_21 PF13304.6 KXT05851.1 - 0.042 13.7 0.0 0.094 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KXT05851.1 - 0.05 13.4 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain RuvB_N PF05496.12 KXT05851.1 - 0.078 12.7 0.0 0.26 11.0 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain End3 PF12761.7 KXT05851.1 - 0.08 13.1 0.7 0.14 12.3 0.7 1.3 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Mg_chelatase PF01078.21 KXT05851.1 - 0.1 11.9 0.1 0.18 11.2 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.6 KXT05851.1 - 0.23 11.9 9.4 6.2 7.3 9.4 2.4 1 1 0 1 1 1 0 AAA domain eRF1_1 PF03463.15 KXT05854.1 - 3.4e-51 172.6 0.1 9.7e-51 171.1 0.0 1.8 2 0 0 2 2 2 1 eRF1 domain 1 eRF1_3 PF03465.15 KXT05854.1 - 4.2e-22 78.8 0.0 8e-22 77.9 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.15 KXT05854.1 - 8.2e-19 68.2 0.0 1.3e-18 67.6 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 DUF4407 PF14362.6 KXT05855.1 - 0.0043 16.5 5.4 0.007 15.8 5.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) HOOK PF05622.12 KXT05855.1 - 0.014 13.6 9.0 0.02 13.0 9.0 1.2 1 0 0 1 1 1 0 HOOK protein Tropomyosin_1 PF12718.7 KXT05855.1 - 0.027 14.7 15.4 0.054 13.6 15.4 1.5 1 0 0 1 1 1 0 Tropomyosin like Macoilin PF09726.9 KXT05855.1 - 0.031 12.9 8.3 0.077 11.5 8.3 1.6 1 0 0 1 1 1 0 Macoilin family ARS2 PF04959.13 KXT05855.1 - 0.039 14.3 2.5 0.11 12.8 2.5 1.7 1 0 0 1 1 1 0 Arsenite-resistance protein 2 IFP_35_N PF07334.13 KXT05855.1 - 0.16 12.1 0.5 0.73 9.9 0.5 2.2 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Fzo_mitofusin PF04799.13 KXT05855.1 - 0.32 10.5 4.5 0.57 9.7 4.5 1.3 1 0 0 1 1 1 0 fzo-like conserved region DUF641 PF04859.12 KXT05855.1 - 0.41 11.0 9.3 2.2 8.6 9.3 2.1 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) HrpB7 PF09486.10 KXT05855.1 - 0.45 10.9 15.3 2.8 8.3 15.2 2.2 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Cnn_1N PF07989.11 KXT05855.1 - 0.72 10.1 7.3 1.8 8.8 3.7 2.4 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 DUF745 PF05335.13 KXT05855.1 - 0.75 9.5 13.3 0.1 12.3 5.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF4201 PF13870.6 KXT05855.1 - 1.2 8.9 9.2 2.3 7.9 9.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) UPF0242 PF06785.11 KXT05855.1 - 1.9 8.6 8.2 3.7 7.6 8.2 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus GAS PF13851.6 KXT05855.1 - 3.3 7.0 11.1 9.4 5.5 11.2 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 KXT05855.1 - 3.5 7.8 19.7 10 6.3 10.4 3.0 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Exonuc_VII_L PF02601.15 KXT05855.1 - 8.1 5.9 8.7 13 5.2 8.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit AA_permease_2 PF13520.6 KXT05856.1 - 1.2e-42 146.3 43.1 1.5e-42 145.9 43.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXT05856.1 - 4.6e-26 91.5 35.1 6.6e-26 90.9 35.1 1.1 1 0 0 1 1 1 1 Amino acid permease NAD_binding_10 PF13460.6 KXT05856.1 - 8.4e-07 29.1 0.0 1.6e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXT05856.1 - 8.5e-07 28.8 0.2 1.7e-06 27.8 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family Aldo_ket_red PF00248.21 KXT05857.1 - 9.1e-22 77.6 0.0 4.4e-19 68.8 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family PilM PF07419.12 KXT05857.1 - 0.0055 16.9 0.0 0.0088 16.2 0.0 1.3 1 0 0 1 1 1 1 PilM Retro_M PF02813.14 KXT05857.1 - 0.21 12.0 0.4 0.57 10.6 0.0 1.9 2 0 0 2 2 2 0 Retroviral M domain Aldo_ket_red PF00248.21 KXT05858.1 - 7.9e-39 133.6 0.0 1.6e-29 103.0 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family PilM PF07419.12 KXT05858.1 - 0.0094 16.1 0.0 0.023 14.9 0.0 1.6 2 0 0 2 2 2 1 PilM Aldo_ket_red PF00248.21 KXT05859.1 - 9.1e-22 77.6 0.0 4.4e-19 68.8 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family PilM PF07419.12 KXT05859.1 - 0.0055 16.9 0.0 0.0088 16.2 0.0 1.3 1 0 0 1 1 1 1 PilM Retro_M PF02813.14 KXT05859.1 - 0.21 12.0 0.4 0.57 10.6 0.0 1.9 2 0 0 2 2 2 0 Retroviral M domain Myb_DNA-bind_3 PF12776.7 KXT05860.1 - 0.0014 19.5 1.9 0.0028 18.6 1.2 1.7 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXT05860.1 - 0.14 12.4 0.3 0.14 12.4 0.3 2.4 2 0 0 2 2 2 0 Myb-like DNA-binding domain Pkinase PF00069.25 KXT05862.1 - 6.4e-74 248.6 0.0 8.5e-74 248.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT05862.1 - 1.9e-39 135.5 0.0 2.8e-39 135.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 KXT05862.1 - 5.3e-21 75.3 0.1 1.6e-09 38.3 0.0 3.5 2 1 1 3 3 3 3 Adenylate sensor of SNF1-like protein kinase UBA_2 PF08587.11 KXT05862.1 - 3.5e-15 55.8 0.1 7.4e-15 54.8 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 KXT05862.1 - 3.5e-07 29.8 0.0 6.2e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KXT05862.1 - 0.0015 17.6 0.1 0.0023 16.9 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KXT05862.1 - 0.0033 17.1 0.1 0.0065 16.1 0.1 1.4 1 0 0 1 1 1 1 RIO1 family YukC PF10140.9 KXT05862.1 - 0.0076 15.1 0.1 0.011 14.5 0.1 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Kdo PF06293.14 KXT05862.1 - 0.017 14.5 0.1 0.037 13.4 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2070 PF09843.9 KXT05863.1 - 0.63 8.3 8.9 0.87 7.8 8.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) adh_short PF00106.25 KXT05865.1 - 2.2e-18 66.4 0.0 2.6e-18 66.2 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT05865.1 - 2e-09 37.4 0.0 2.2e-09 37.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT05865.1 - 0.0032 17.4 0.0 0.0037 17.2 0.0 1.1 1 0 0 1 1 1 1 KR domain MCM PF00493.23 KXT05874.1 - 9.4e-97 322.5 0.2 1.5e-96 321.9 0.2 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KXT05874.1 - 3.4e-30 104.5 0.0 6.2e-30 103.6 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KXT05874.1 - 2e-22 79.4 0.4 4.1e-22 78.4 0.4 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KXT05874.1 - 1.7e-10 41.4 0.2 5.1e-10 39.9 0.2 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KXT05874.1 - 9.9e-07 28.3 0.0 1.2e-05 24.8 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KXT05874.1 - 0.003 17.4 0.0 0.0067 16.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KXT05874.1 - 0.068 13.2 0.0 0.25 11.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KXT05874.1 - 0.089 12.5 0.0 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Sorting_nexin PF03700.13 KXT05874.1 - 0.46 11.1 10.4 1 9.9 10.4 1.6 1 0 0 1 1 1 0 Sorting nexin, N-terminal domain Fungal_trans PF04082.18 KXT05876.1 - 8e-13 48.0 2.8 1.4e-12 47.3 2.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT05876.1 - 4.6e-07 29.8 17.5 8.8e-07 28.9 17.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pex14_N PF04695.13 KXT05876.1 - 0.19 12.4 14.9 0.067 13.8 8.7 2.5 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3290 PF11694.8 KXT05877.1 - 0.1 12.5 1.2 0.64 10.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) Alb1 PF09135.11 KXT05879.1 - 8.6e-22 78.0 13.0 1.6e-21 77.2 13.0 1.4 1 0 0 1 1 1 1 Alb1 NARP1 PF12569.8 KXT05879.1 - 0.29 10.0 12.2 0.37 9.7 12.2 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SOBP PF15279.6 KXT05879.1 - 2.9 8.4 7.7 3.2 8.3 7.7 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein V_ATPase_I PF01496.19 KXT05879.1 - 4.6 5.0 5.9 5.4 4.8 5.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HIG_1_N PF04588.13 KXT05881.1 - 5.5e-06 26.5 0.1 5.5e-06 26.5 0.1 1.8 2 0 0 2 2 2 1 Hypoxia induced protein conserved region DUF1580 PF07618.11 KXT05881.1 - 0.08 12.6 0.1 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1580) PPR_3 PF13812.6 KXT05882.1 - 4.1e-15 55.6 2.4 0.055 13.5 0.0 6.3 5 1 1 6 6 6 4 Pentatricopeptide repeat domain PPR_2 PF13041.6 KXT05882.1 - 1.8e-08 34.5 2.4 0.13 12.4 0.0 6.1 6 1 1 7 7 7 2 PPR repeat family PPR_long PF17177.4 KXT05882.1 - 2.2e-06 27.2 0.4 0.81 9.0 0.0 4.5 3 1 2 5 5 5 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 KXT05882.1 - 0.00056 19.6 5.1 0.65 9.7 0.1 5.6 7 0 0 7 7 7 1 PPR repeat PPR PF01535.20 KXT05882.1 - 0.00066 19.8 3.7 0.23 11.8 0.0 5.0 5 1 0 5 5 5 1 PPR repeat TPR_19 PF14559.6 KXT05882.1 - 0.00098 19.6 0.5 0.076 13.5 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat XPC-binding PF09280.11 KXT05883.1 - 1e-23 82.8 17.3 1e-23 82.8 17.3 2.6 2 0 0 2 2 2 1 XPC-binding domain ubiquitin PF00240.23 KXT05883.1 - 2.1e-20 72.2 0.2 4.6e-20 71.1 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 KXT05883.1 - 8.1e-20 70.3 10.7 3.7e-12 45.9 0.5 2.9 3 0 0 3 3 3 2 UBA/TS-N domain Rad60-SLD PF11976.8 KXT05883.1 - 1.2e-07 31.5 1.4 2.4e-07 30.5 0.3 2.1 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KXT05883.1 - 0.034 14.6 0.1 0.076 13.5 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KXT05883.1 - 0.067 13.3 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.10 KXT05883.1 - 0.087 12.7 0.0 5.6 6.9 0.0 2.7 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain Rick_17kDa_Anti PF05433.15 KXT05884.1 - 0.00036 20.3 10.3 0.00036 20.3 10.3 2.4 3 0 0 3 3 3 1 Glycine zipper 2TM domain TraT PF05818.12 KXT05884.1 - 4.3 7.0 9.3 0.46 10.1 0.5 2.3 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein MFS_1 PF07690.16 KXT05885.1 - 2e-44 152.0 49.1 2e-44 152.0 49.1 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXT05885.1 - 7.2e-18 64.7 8.9 7.2e-18 64.7 8.9 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KXT05885.1 - 8.8e-14 50.8 27.4 8.8e-14 50.8 27.4 2.5 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Ysc84 PF04366.12 KXT05885.1 - 0.093 12.5 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 Las17-binding protein actin regulator DUF2919 PF11143.8 KXT05885.1 - 0.18 12.1 0.1 0.18 12.1 0.1 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF2919) DAO PF01266.24 KXT05886.1 - 7.7e-32 111.2 0.0 1.5e-31 110.3 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXT05886.1 - 0.00039 20.5 0.1 0.0055 16.7 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KXT05886.1 - 0.00068 19.8 0.0 0.0039 17.4 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 KXT05886.1 - 0.0031 17.6 0.0 0.0055 16.8 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 KXT05886.1 - 0.024 13.7 0.0 4.5 6.2 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.14 KXT05886.1 - 0.029 13.6 0.0 0.14 11.4 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 KXT05886.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 ThiF family Glu_dehyd_C PF16912.5 KXT05886.1 - 0.16 11.5 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KXT05886.1 - 0.18 11.1 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PUF PF00806.19 KXT05888.1 - 1.8e-53 175.3 8.2 6.7e-07 28.7 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat PUF PF00806.19 KXT05890.1 - 5.6e-54 176.9 8.2 5.8e-07 28.9 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Cauli_VI PF01693.16 KXT05891.1 - 2.4e-39 133.4 4.4 2.1e-20 72.8 0.1 2.5 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.24 KXT05891.1 - 1e-34 119.8 0.3 5.3e-27 94.8 0.0 2.4 2 0 0 2 2 2 2 RNase H RVT_3 PF13456.6 KXT05891.1 - 0.006 16.4 0.0 0.032 14.0 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase-like Arm-DNA-bind_4 PF14657.6 KXT05891.1 - 0.013 15.3 0.4 0.042 13.6 0.4 1.9 1 0 0 1 1 1 0 Arm DNA-binding domain GARS_A PF01071.19 KXT05891.1 - 0.12 12.1 0.0 0.78 9.5 0.0 2.1 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain TOPRIM_C PF16898.5 KXT05891.1 - 0.12 12.6 1.4 16 5.8 0.1 2.6 2 0 0 2 2 2 0 C-terminal associated domain of TOPRIM YmgB PF10798.8 KXT05891.1 - 0.17 11.7 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 Biofilm development protein YmgB/AriR SUZ PF12752.7 KXT05891.1 - 0.38 11.6 2.6 0.32 11.8 0.4 2.1 2 0 0 2 2 2 0 SUZ domain Glyco_hydro_1 PF00232.18 KXT05892.1 - 3.6e-68 230.0 3.1 1.9e-65 221.0 3.1 2.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 Mid1 PF12929.7 KXT05893.1 - 1.2e-153 512.4 5.3 1.4e-153 512.1 5.3 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 KXT05893.1 - 0.0016 19.0 7.6 0.11 13.1 3.3 2.7 2 1 0 2 2 2 2 Fz domain F-box-like PF12937.7 KXT05894.1 - 4.7e-07 29.6 0.4 1.1e-06 28.4 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXT05894.1 - 1.6e-06 27.9 1.3 3.9e-06 26.6 1.3 1.7 1 0 0 1 1 1 1 F-box domain Glyco_hydro_47 PF01532.20 KXT05895.1 - 1.7e-172 574.5 0.0 2e-172 574.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PPP5 PF08321.12 KXT05896.1 - 1.9e-34 117.8 2.8 1.1e-33 115.3 0.5 2.4 2 0 0 2 2 2 1 PPP5 TPR repeat region Metallophos PF00149.28 KXT05896.1 - 7.6e-32 111.5 0.1 1.2e-31 110.8 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_1 PF00515.28 KXT05896.1 - 2.2e-15 55.7 4.7 5.1e-06 26.1 0.3 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KXT05896.1 - 7.5e-10 38.2 3.3 0.0021 18.0 0.2 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 KXT05896.1 - 7e-07 28.8 3.1 0.014 15.0 0.2 2.6 1 1 1 2 2 2 2 TPR repeat TPR_17 PF13431.6 KXT05896.1 - 3.4e-05 23.9 1.5 0.074 13.5 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXT05896.1 - 0.00046 20.8 0.5 0.0044 17.6 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KXT05896.1 - 0.017 15.3 0.0 0.034 14.3 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat MIT PF04212.18 KXT05896.1 - 0.053 13.6 0.9 0.18 11.9 0.2 2.1 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_8 PF13181.6 KXT05896.1 - 0.26 11.6 0.1 0.26 11.6 0.1 3.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Asp PF00026.23 KXT05897.1 - 1.6e-76 257.8 7.5 2e-76 257.4 7.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXT05897.1 - 1.7e-10 41.4 7.4 7.4e-10 39.3 3.9 3.4 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KXT05897.1 - 2e-05 25.1 0.1 1.2 9.8 0.1 3.7 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 KXT05897.1 - 0.14 12.0 0.0 0.78 9.5 0.0 2.1 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal QCR10 PF09796.9 KXT05898.1 - 4.4e-25 87.5 0.2 6.1e-25 87.1 0.2 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) CPBP PF02517.16 KXT05899.1 - 1e-13 51.4 12.4 1e-13 51.4 12.4 2.9 1 1 1 2 2 2 1 CPBP intramembrane metalloprotease Aa_trans PF01490.18 KXT05899.1 - 0.025 13.3 1.5 0.18 10.4 0.2 2.2 2 0 0 2 2 2 0 Transmembrane amino acid transporter protein Med6 PF04934.14 KXT05900.1 - 5.6e-30 103.9 0.0 8.2e-30 103.3 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component PanZ PF12568.8 KXT05900.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ DUF3402 PF11882.8 KXT05901.1 - 6.3e-176 586.0 0.0 1.1e-175 585.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.13 KXT05901.1 - 8.8e-88 294.2 0.0 1.4e-87 293.5 0.0 1.4 1 0 0 1 1 1 1 N1221-like protein Glyco_hydro_92 PF07971.12 KXT05902.1 - 2.4e-142 475.1 0.2 2.9e-142 474.8 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KXT05902.1 - 5.1e-53 180.4 0.9 8e-53 179.8 0.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain HLH PF00010.26 KXT05903.1 - 1.2e-12 47.6 0.0 2.2e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HALZ PF02183.18 KXT05903.1 - 0.036 14.3 0.6 0.37 11.1 0.1 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper ZapB PF06005.12 KXT05903.1 - 0.12 12.9 0.4 0.56 10.7 0.0 2.2 3 0 0 3 3 3 0 Cell division protein ZapB Cnn_1N PF07989.11 KXT05903.1 - 0.15 12.3 0.0 0.4 10.9 0.0 1.7 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Shugoshin_N PF07558.11 KXT05903.1 - 0.2 11.6 0.0 0.38 10.7 0.0 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region DivIC PF04977.15 KXT05903.1 - 0.22 11.3 0.2 4.4 7.1 0.0 2.2 2 0 0 2 2 2 0 Septum formation initiator Pox_A_type_inc PF04508.12 KXT05903.1 - 0.25 11.2 0.1 0.25 11.2 0.1 1.7 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Vps51 PF08700.11 KXT05904.1 - 3.9e-14 52.5 3.1 1.4e-13 50.7 0.0 3.3 4 0 0 4 4 4 1 Vps51/Vps67 Dor1 PF04124.12 KXT05904.1 - 0.0083 14.8 8.2 0.15 10.7 2.5 3.3 2 1 1 3 3 3 2 Dor1-like family COG2 PF06148.11 KXT05904.1 - 0.11 12.6 5.2 0.05 13.7 1.2 2.6 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Ribosomal_S25 PF03297.15 KXT05905.1 - 2.2e-38 130.5 4.1 2.4e-38 130.4 4.1 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_DeoR PF08220.12 KXT05905.1 - 0.001 18.8 0.1 0.0014 18.3 0.1 1.3 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_24 PF13412.6 KXT05905.1 - 0.0014 18.1 0.1 0.0029 17.1 0.1 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Rrf2 PF02082.20 KXT05905.1 - 0.0019 18.5 0.1 0.0028 18.0 0.1 1.2 1 0 0 1 1 1 1 Transcriptional regulator MarR_2 PF12802.7 KXT05905.1 - 0.0056 16.5 0.0 0.0072 16.2 0.0 1.2 1 0 0 1 1 1 1 MarR family GntR PF00392.21 KXT05905.1 - 0.04 13.6 0.0 0.05 13.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family DUF1744 PF08490.12 KXT05905.1 - 0.088 11.4 0.0 0.096 11.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1744) DUF3328 PF11807.8 KXT05906.1 - 1.9e-29 103.0 0.4 2.2e-29 102.8 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) RRP36 PF06102.12 KXT05909.1 - 1.3e-47 161.8 38.2 1.3e-47 161.8 38.2 2.3 2 0 0 2 2 2 1 rRNA biogenesis protein RRP36 SlyX PF04102.12 KXT05909.1 - 1.7 9.3 13.2 15 6.3 3.1 3.8 2 1 1 3 3 3 0 SlyX MitMem_reg PF13012.6 KXT05911.1 - 3.1e-37 127.4 0.0 5.6e-37 126.6 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KXT05911.1 - 3.7e-31 107.5 0.1 1.6e-30 105.5 0.0 1.9 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Mak10 PF04112.13 KXT05911.1 - 0.0063 16.0 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase tRNA_bind_2 PF13725.6 KXT05911.1 - 0.15 11.7 10.0 0.22 11.2 10.0 1.2 1 0 0 1 1 1 0 Possible tRNA binding domain Connexin PF00029.19 KXT05911.1 - 0.97 9.1 4.3 1.5 8.5 4.3 1.2 1 0 0 1 1 1 0 Connexin O-antigen_lig PF13425.6 KXT05911.1 - 5.6 5.6 5.1 7.6 5.2 5.1 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein PhoD PF09423.10 KXT05912.1 - 6.7e-113 377.3 1.0 8.3e-113 377.0 1.0 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 KXT05912.1 - 2.4e-33 114.5 0.3 6.7e-33 113.1 0.3 1.8 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 KXT05912.1 - 5.8e-05 23.6 1.9 0.00011 22.6 0.5 2.2 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain PMT PF02366.18 KXT05913.1 - 1.2e-90 303.4 15.4 1.2e-90 303.4 15.4 1.9 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KXT05913.1 - 1.2e-63 214.3 18.9 1.2e-63 214.3 18.9 2.6 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KXT05913.1 - 7.5e-35 120.5 0.6 1.2e-34 119.8 0.6 1.2 1 0 0 1 1 1 1 MIR domain MreB_Mbl PF06723.13 KXT05914.1 - 0.022 13.6 0.0 3.6 6.3 0.0 2.6 2 1 0 2 2 2 0 MreB/Mbl protein HSP70 PF00012.20 KXT05914.1 - 0.035 12.3 0.1 0.05 11.8 0.1 1.2 1 0 0 1 1 1 0 Hsp70 protein Peptidase_M22 PF00814.25 KXT05914.1 - 0.062 13.0 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Glycoprotease family Coprogen_oxidas PF01218.18 KXT05915.1 - 4.7e-147 488.4 0.1 5.7e-147 488.1 0.1 1.1 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase SWIRM PF04433.17 KXT05916.1 - 5e-10 39.6 0.1 9.4e-10 38.7 0.1 1.4 1 0 0 1 1 1 1 SWIRM domain DUF4381 PF14316.6 KXT05917.1 - 0.0044 17.3 0.2 0.0063 16.8 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) CD34_antigen PF06365.12 KXT05917.1 - 0.022 14.3 0.1 0.032 13.8 0.1 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family Ni_hydr_CYTB PF01292.20 KXT05917.1 - 0.037 13.6 0.0 0.047 13.3 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 MLANA PF14991.6 KXT05917.1 - 0.064 13.5 0.0 0.16 12.2 0.0 1.7 2 0 0 2 2 2 0 Protein melan-A HemY_N PF07219.13 KXT05917.1 - 0.077 13.2 0.2 0.12 12.6 0.2 1.4 1 0 0 1 1 1 0 HemY protein N-terminus OppC_N PF12911.7 KXT05917.1 - 0.17 11.9 1.5 0.17 11.9 0.2 1.7 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Tad PF13400.6 KXT05917.1 - 1.6 9.1 5.8 3.8 7.9 5.8 1.6 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like NUDIX PF00293.28 KXT05918.1 - 2.4e-07 30.8 0.0 3.4e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Chromo PF00385.24 KXT05919.1 - 3.2e-12 46.1 0.7 7.6e-12 45.0 0.7 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-CCCH_4 PF18044.1 KXT05919.1 - 0.0039 17.0 1.0 0.0039 17.0 1.0 3.5 3 0 0 3 3 3 1 CCCH-type zinc finger zf-CCCH_3 PF15663.5 KXT05919.1 - 2 8.7 15.0 13 6.0 1.4 3.6 2 1 1 3 3 3 0 Zinc-finger containing family Torus PF16131.5 KXT05919.1 - 6.4 7.5 12.4 7.3 7.3 1.8 3.5 2 1 0 3 3 3 0 Torus domain Romo1 PF10247.9 KXT05920.1 - 0.082 13.3 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 SKG6 PF08693.10 KXT05920.1 - 0.12 11.8 0.1 0.27 10.7 0.1 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Podoplanin PF05808.11 KXT05920.1 - 0.14 12.2 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Podoplanin AMP-binding PF00501.28 KXT05921.1 - 4.8e-93 312.0 0.0 5.9e-93 311.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme MMR_HSR1 PF01926.23 KXT05922.1 - 0.00061 19.9 0.8 0.43 10.7 0.0 3.6 3 1 0 3 3 3 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 KXT05922.1 - 0.0012 18.9 5.4 0.0022 18.1 1.2 3.3 2 1 0 2 2 2 1 Dynamin family AAA_22 PF13401.6 KXT05922.1 - 0.0027 18.0 2.4 0.17 12.2 0.0 4.2 5 0 0 5 5 5 1 AAA domain AIG1 PF04548.16 KXT05922.1 - 0.027 13.8 0.6 0.15 11.3 0.2 2.6 3 0 0 3 3 3 0 AIG1 family dCache_3 PF14827.6 KXT05922.1 - 4.2 6.9 6.1 9.3 5.8 1.8 2.8 3 0 0 3 3 3 0 Double sensory domain of two-component sensor kinase SKG6 PF08693.10 KXT05923.1 - 0.0016 17.8 0.7 0.0037 16.6 0.7 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF347 PF03988.12 KXT05923.1 - 0.07 13.3 0.2 0.18 12.0 0.2 1.7 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) EphA2_TM PF14575.6 KXT05923.1 - 5.3 8.0 0.0 5.3 8.0 0.0 3.4 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Rep_fac_C PF08542.11 KXT05924.1 - 1.1e-23 83.4 0.0 3.9e-23 81.6 0.0 2.0 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 KXT05924.1 - 9.3e-12 45.0 0.0 2.4e-08 33.9 0.0 2.3 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 KXT05924.1 - 1.6e-11 44.7 0.0 2.7e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KXT05924.1 - 1.8e-06 28.0 0.0 4.1e-06 26.8 0.0 1.6 1 1 1 2 2 1 1 AAA domain AAA_16 PF13191.6 KXT05924.1 - 2.1e-06 28.2 0.0 0.00033 21.1 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KXT05924.1 - 4e-05 23.9 0.1 0.075 13.3 0.0 2.6 1 1 1 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 KXT05924.1 - 6.8e-05 22.7 0.0 0.00013 21.8 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.12 KXT05924.1 - 0.00024 20.9 0.0 0.00058 19.6 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 KXT05924.1 - 0.00047 20.0 0.0 0.001 19.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KXT05924.1 - 0.0016 17.8 0.0 0.02 14.3 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI DNA_pol3_delta PF06144.13 KXT05924.1 - 0.0023 17.8 0.0 0.0036 17.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 KXT05924.1 - 0.0029 17.5 0.0 0.005 16.8 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 KXT05924.1 - 0.0068 16.7 0.0 0.02 15.3 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain TniB PF05621.11 KXT05924.1 - 0.01 15.2 0.0 2 7.8 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein MeaB PF03308.16 KXT05924.1 - 0.011 14.7 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 KXT05924.1 - 0.021 14.5 0.0 0.059 13.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KXT05924.1 - 0.042 13.7 0.1 0.14 12.1 0.1 1.9 1 1 1 2 2 2 0 NTPase KTI12 PF08433.10 KXT05924.1 - 0.066 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_11 PF13086.6 KXT05924.1 - 0.071 12.9 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KXT05924.1 - 0.073 13.4 0.1 0.63 10.4 0.0 2.1 1 1 1 2 2 2 0 AAA domain RNA_helicase PF00910.22 KXT05924.1 - 0.12 12.8 0.0 0.7 10.3 0.0 2.1 1 1 0 1 1 1 0 RNA helicase DEAD PF00270.29 KXT05924.1 - 0.15 11.8 0.1 1.6 8.4 0.0 2.2 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_30 PF13604.6 KXT05924.1 - 0.15 11.8 0.1 0.55 9.9 0.1 1.9 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KXT05924.1 - 0.19 11.8 0.2 0.55 10.2 0.1 1.9 2 1 0 2 2 1 0 AAA domain (dynein-related subfamily) MRJP PF03022.16 KXT05925.1 - 1.1e-29 103.7 0.0 1.5e-29 103.3 0.0 1.1 1 0 0 1 1 1 1 Major royal jelly protein SGL PF08450.12 KXT05925.1 - 0.00022 20.9 0.4 0.0048 16.5 0.0 2.7 2 2 1 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 KXT05925.1 - 0.22 11.6 0.5 47 4.3 0.0 4.2 5 0 0 5 5 5 0 NHL repeat 6PF2K PF01591.18 KXT05926.1 - 2.5e-70 236.2 1.4 1.7e-48 164.9 1.2 2.4 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KXT05926.1 - 3.1e-27 95.5 0.0 4.9e-22 78.6 0.0 2.6 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Pet100 PF09803.9 KXT05926.1 - 7.3e-20 71.3 0.7 3.7e-19 69.0 0.7 2.3 1 0 0 1 1 1 1 Pet100 AAA_33 PF13671.6 KXT05926.1 - 0.00013 22.1 0.8 0.13 12.4 0.0 2.9 3 0 0 3 3 3 2 AAA domain KTI12 PF08433.10 KXT05926.1 - 0.04 13.4 0.5 0.1 12.0 0.0 1.9 2 0 0 2 2 2 0 Chromatin associated protein KTI12 TRAPPC10 PF12584.8 KXT05927.1 - 1.5e-16 60.5 0.0 2.5e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 PIF6 PF05341.11 KXT05927.1 - 0.042 14.0 0.0 3.8 7.7 0.0 2.6 2 0 0 2 2 2 0 Per os infectivity factor 6 DUF202 PF02656.15 KXT05928.1 - 0.0035 17.7 5.6 0.009 16.4 5.6 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF202) DUF202 PF02656.15 KXT05929.1 - 0.0055 17.1 5.7 0.014 15.8 5.7 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF202) HD PF01966.22 KXT05930.1 - 4.5e-07 30.1 0.1 9.9e-07 29.0 0.0 1.6 2 0 0 2 2 2 1 HD domain Lysine_decarbox PF03641.14 KXT05931.1 - 7.5e-32 110.2 0.3 9.9e-32 109.8 0.3 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 KXT05931.1 - 4.4e-06 26.4 0.8 5e-06 26.2 0.8 1.2 1 0 0 1 1 1 1 SLOG cluster4 family LSDAT_prok PF18171.1 KXT05931.1 - 0.029 13.6 0.3 0.045 13.0 0.3 1.3 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote DAGK_acc PF00609.19 KXT05931.1 - 0.11 12.8 0.1 0.19 12.1 0.0 1.5 2 0 0 2 2 2 0 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 KXT05931.1 - 0.31 10.7 1.5 17 5.0 0.1 2.3 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain AMP-binding PF00501.28 KXT05933.1 - 4e-21 75.1 0.0 6.5e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXT05933.1 - 1.3e-20 74.1 2.4 2.6e-20 73.2 2.4 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PepSY PF03413.19 KXT05933.1 - 0.15 12.7 0.4 0.63 10.6 0.1 2.1 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain SWIM PF04434.17 KXT05934.1 - 0.013 15.2 7.1 0.024 14.3 0.1 3.0 4 0 0 4 4 4 0 SWIM zinc finger PBP1_TM PF14812.6 KXT05935.1 - 0.41 11.0 5.3 0.99 9.8 5.3 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Syja_N PF02383.18 KXT05936.1 - 2e-89 300.1 0.1 3.4e-89 299.3 0.1 1.4 1 0 0 1 1 1 1 SacI homology domain adh_short PF00106.25 KXT05936.1 - 4.3e-42 143.8 0.0 7.2e-42 143.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Peroxidase_2 PF01328.17 KXT05936.1 - 4.7e-40 138.1 0.0 1.1e-39 136.9 0.0 1.7 1 0 0 1 1 1 1 Peroxidase, family 2 hSac2 PF12456.8 KXT05936.1 - 6.8e-34 116.0 0.0 2.7e-33 114.1 0.0 2.0 2 0 0 2 2 2 1 Inositol phosphatase adh_short_C2 PF13561.6 KXT05936.1 - 1.8e-30 106.3 0.0 3.9e-30 105.2 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT05936.1 - 2.1e-06 27.8 0.0 5.7e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 KXT05936.1 - 0.0083 15.5 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Peripla_BP_6 PF13458.6 KXT05936.1 - 0.03 14.0 1.7 0.054 13.2 0.1 2.1 3 0 0 3 3 3 0 Periplasmic binding protein Eno-Rase_NADH_b PF12242.8 KXT05936.1 - 0.25 11.1 0.6 0.61 9.9 0.6 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Usp PF00582.26 KXT05936.1 - 3.2 8.3 6.9 54 4.3 1.9 3.5 3 0 0 3 3 3 0 Universal stress protein family CFIA_Pcf11 PF11526.8 KXT05937.1 - 3e-05 24.4 0.2 7.9e-05 23.1 0.2 1.7 1 0 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 VHS PF00790.19 KXT05937.1 - 0.0019 18.1 0.0 0.0038 17.1 0.0 1.5 1 0 0 1 1 1 1 VHS domain CTD_bind PF04818.13 KXT05937.1 - 0.02 15.7 0.0 0.076 13.9 0.0 2.0 2 0 0 2 2 2 0 RNA polymerase II-binding domain. zf_UBZ PF18439.1 KXT05937.1 - 2.2 8.0 6.2 0.73 9.5 1.6 2.5 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger SAE2 PF08573.10 KXT05938.1 - 2e-26 93.3 0.3 2e-26 93.3 0.3 3.5 4 0 0 4 4 4 1 DNA repair protein endonuclease SAE2/CtIP C-terminus DivIC PF04977.15 KXT05938.1 - 0.015 15.0 2.3 0.077 12.8 0.1 2.6 2 0 0 2 2 2 0 Septum formation initiator HALZ PF02183.18 KXT05938.1 - 0.093 13.0 3.2 2.1 8.6 0.2 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper Shugoshin_N PF07558.11 KXT05938.1 - 0.14 12.0 0.4 0.32 10.9 0.4 1.5 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region YabA PF06156.13 KXT05938.1 - 1.7 9.3 4.5 2 9.1 0.9 2.7 2 1 0 2 2 2 0 Initiation control protein YabA DUF4665 PF15679.5 KXT05938.1 - 2.2 9.0 5.9 4.7 7.9 2.9 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4665) Arylsulfotran_2 PF14269.6 KXT05939.1 - 1.7e-44 152.4 1.1 2.9e-44 151.6 1.1 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) zf-CCHC PF00098.23 KXT05939.1 - 3.5e-33 112.2 55.3 4e-07 29.8 2.4 6.3 6 0 0 6 6 6 6 Zinc knuckle Arylsulfotrans PF05935.11 KXT05939.1 - 7.2e-10 38.3 3.2 4.6e-09 35.7 3.2 2.5 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) zf-CCHC_3 PF13917.6 KXT05939.1 - 0.00063 19.7 38.9 0.14 12.2 0.7 5.3 3 1 2 5 5 5 5 Zinc knuckle zf-CCHC_4 PF14392.6 KXT05939.1 - 0.001 18.7 34.3 0.055 13.2 0.6 6.2 6 0 0 6 6 6 5 Zinc knuckle zf-CCHC_5 PF14787.6 KXT05939.1 - 3.7 7.3 26.2 0.38 10.5 0.8 5.3 4 1 1 5 5 5 0 GAG-polyprotein viral zinc-finger DPBB_1 PF03330.18 KXT05940.1 - 1.3e-08 35.0 2.5 2e-08 34.4 0.1 2.4 2 1 0 2 2 2 1 Lytic transglycolase Barwin PF00967.17 KXT05940.1 - 7.5e-05 22.6 0.3 0.00015 21.6 0.3 1.5 1 0 0 1 1 1 1 Barwin family ATP-synt_ab PF00006.25 KXT05941.1 - 3.3e-62 209.9 0.0 6.6e-62 208.9 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KXT05941.1 - 3e-22 78.9 1.4 7.5e-22 77.6 1.0 2.0 2 0 0 2 2 1 1 ATP synthase alpha/beta family, beta-barrel domain ATPase PF06745.13 KXT05941.1 - 0.0043 16.4 0.2 0.0082 15.5 0.2 1.5 1 0 0 1 1 1 1 KaiC RsgA_GTPase PF03193.16 KXT05941.1 - 0.013 15.4 0.3 0.033 14.1 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase NB-ARC PF00931.22 KXT05941.1 - 0.015 14.5 0.7 0.1 11.7 0.1 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA PF00004.29 KXT05941.1 - 0.02 15.3 0.1 0.87 10.0 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KXT05941.1 - 0.046 13.6 0.3 0.14 12.1 0.1 1.8 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.6 KXT05941.1 - 0.071 13.4 0.9 0.48 10.7 0.2 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KXT05941.1 - 0.077 13.4 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase T3SS_ATPase_C PF18269.1 KXT05941.1 - 0.083 12.8 1.0 0.57 10.1 1.0 2.2 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain AAA_16 PF13191.6 KXT05941.1 - 0.1 12.9 0.2 0.45 10.9 0.2 2.1 1 1 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 KXT05941.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF4618 PF15397.6 KXT05941.1 - 0.14 11.6 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) AbfB PF05270.13 KXT05942.1 - 0.096 12.7 9.4 2.8 7.9 0.1 3.4 1 1 2 3 3 3 0 Alpha-L-arabinofuranosidase B (ABFB) domain Bile_Hydr_Trans PF04775.14 KXT05942.1 - 0.1 12.6 0.6 0.84 9.7 0.1 2.0 1 1 1 2 2 2 0 Acyl-CoA thioester hydrolase/BAAT N-terminal region DUF3328 PF11807.8 KXT05943.1 - 2.1e-37 129.0 1.5 2.5e-37 128.8 1.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) SPX PF03105.19 KXT05944.1 - 1.9 8.3 21.9 2.4 8.0 21.9 1.1 1 0 0 1 1 1 0 SPX domain Arf PF00025.21 KXT05945.1 - 5.5e-42 143.2 0.1 1.3e-27 96.3 0.0 2.0 2 0 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.20 KXT05945.1 - 3.5e-15 56.0 0.0 1.3e-07 31.2 0.0 2.0 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KXT05945.1 - 3.5e-10 40.1 0.0 1.1e-09 38.6 0.0 1.8 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KXT05945.1 - 7.3e-10 38.6 0.0 8.5e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 KXT05945.1 - 5.5e-09 35.8 0.0 3.5e-05 23.5 0.0 2.1 2 0 0 2 2 2 2 Ras family SRPRB PF09439.10 KXT05945.1 - 2.5e-07 30.3 0.0 4e-06 26.4 0.0 2.0 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KXT05945.1 - 8.8e-06 25.8 0.0 1.4e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KXT05945.1 - 1.4e-05 24.8 0.0 0.0037 16.8 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain TniB PF05621.11 KXT05945.1 - 0.01 15.3 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein FeoB_N PF02421.18 KXT05945.1 - 0.035 13.6 0.0 0.13 11.8 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_22 PF13401.6 KXT05945.1 - 0.04 14.2 0.0 0.13 12.5 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KXT05945.1 - 0.081 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF382 PF04037.13 KXT05947.1 - 3.2e-57 192.1 0.2 3.2e-57 192.1 0.2 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF382) PSP PF04046.16 KXT05947.1 - 5.1e-20 71.1 5.1 1.1e-19 69.9 5.1 1.6 1 0 0 1 1 1 1 PSP DUF382 PF04037.13 KXT05948.1 - 3.2e-57 192.1 0.2 3.2e-57 192.1 0.2 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF382) PSP PF04046.16 KXT05948.1 - 5.1e-20 71.1 5.1 1.1e-19 69.9 5.1 1.6 1 0 0 1 1 1 1 PSP APG6_N PF17675.1 KXT05949.1 - 1.4 9.4 9.7 2.3 8.8 9.7 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region IPPT PF01715.17 KXT05950.1 - 3.2e-66 223.4 1.6 4.6e-66 222.9 1.6 1.2 1 0 0 1 1 1 1 IPP transferase AAA_33 PF13671.6 KXT05950.1 - 2e-05 24.8 0.1 0.025 14.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain IPT PF01745.16 KXT05950.1 - 0.00018 20.9 0.0 0.00056 19.4 0.0 1.8 2 0 0 2 2 2 1 Isopentenyl transferase zf-C2H2_jaz PF12171.8 KXT05950.1 - 0.0006 20.0 0.0 0.0011 19.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding AAA_18 PF13238.6 KXT05950.1 - 0.0017 18.9 0.7 0.21 12.1 0.0 3.3 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KXT05950.1 - 0.0061 17.0 0.1 0.019 15.3 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 KXT05950.1 - 0.0065 17.0 0.1 0.024 15.1 0.0 2.2 2 1 0 2 2 2 1 ABC transporter AAA_28 PF13521.6 KXT05950.1 - 0.01 16.1 2.2 0.24 11.6 0.0 3.2 3 1 0 4 4 4 0 AAA domain CTU2 PF10288.9 KXT05950.1 - 0.027 14.7 0.1 0.058 13.6 0.1 1.6 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 DUF87 PF01935.17 KXT05950.1 - 0.051 13.7 0.6 0.62 10.1 0.0 2.5 2 1 0 2 2 2 0 Helicase HerA, central domain Hydin_ADK PF17213.3 KXT05950.1 - 0.095 13.0 0.5 0.76 10.0 0.1 2.3 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain zf-C2H2_2 PF12756.7 KXT05950.1 - 0.11 12.8 0.6 0.21 11.9 0.6 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 KXT05950.1 - 0.17 12.4 0.8 0.42 11.2 0.2 2.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type E1-E2_ATPase PF00122.20 KXT05951.1 - 2e-19 69.8 0.0 6.1e-19 68.2 0.0 1.9 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KXT05951.1 - 1.2e-16 61.6 1.5 7e-10 39.5 1.7 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXT05951.1 - 0.0022 18.0 0.1 0.009 16.1 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KXT05951.1 - 0.0077 16.0 0.3 0.049 13.4 0.2 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KXT05951.1 - 0.036 13.8 0.0 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus Fungal_trans_2 PF11951.8 KXT05952.1 - 1.3e-30 106.5 0.4 1.8e-30 106.0 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT05952.1 - 1.2e-07 31.7 9.1 2.2e-07 30.9 9.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spt4 PF06093.13 KXT05953.1 - 4.3e-30 103.6 0.7 5.7e-30 103.2 0.7 1.2 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger MBG_2 PF18676.1 KXT05953.1 - 0.0075 16.9 0.1 0.012 16.3 0.1 1.3 1 0 0 1 1 1 1 MBG domain (YGX type) Cys_Met_Meta_PP PF01053.20 KXT05954.1 - 3e-149 496.8 0.0 3.4e-149 496.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KXT05954.1 - 7e-10 38.8 0.1 1.2e-09 38.0 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 KXT05954.1 - 1.1e-08 34.7 0.0 3.3e-08 33.1 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KXT05954.1 - 4.7e-08 32.4 0.1 7.7e-08 31.7 0.1 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KXT05954.1 - 0.00023 20.6 0.0 0.00038 19.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 KXT05954.1 - 0.00036 19.2 0.1 0.00047 18.8 0.1 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase Asparaginase_C PF17763.1 KXT05954.1 - 0.018 15.3 0.0 0.053 13.7 0.0 1.7 1 0 0 1 1 1 0 Glutaminase/Asparaginase C-terminal domain Chs7 PF12271.8 KXT05955.1 - 4.8e-108 360.9 2.4 5.4e-108 360.7 2.4 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone FixQ PF05545.11 KXT05955.1 - 0.37 10.8 7.6 3.3 7.7 0.0 3.8 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ Hemolysin_N PF12563.8 KXT05956.1 - 0.027 14.1 0.0 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 Hemolytic toxin N terminal Bac_rhamnosid_C PF17390.2 KXT05958.1 - 4.9e-11 42.3 0.1 1.5e-10 40.7 0.1 1.9 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Ank_3 PF13606.6 KXT05960.1 - 3.4e-17 60.7 0.1 0.00011 22.4 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_2 PF12796.7 KXT05960.1 - 2.4e-15 56.9 0.1 2.8e-06 27.8 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXT05960.1 - 1.7e-14 53.9 0.1 0.00026 21.5 0.0 5.2 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 KXT05960.1 - 1.8e-11 43.9 0.5 0.037 14.5 0.0 5.9 5 1 1 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 KXT05960.1 - 1.6e-10 41.0 0.1 6.2e-05 23.2 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeats (many copies) DUF3447 PF11929.8 KXT05960.1 - 0.05 13.6 0.0 0.12 12.3 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) F-box-like PF12937.7 KXT05961.1 - 2.7e-05 24.0 0.3 5e-05 23.1 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXT05961.1 - 9e-05 22.2 0.1 0.00016 21.4 0.1 1.5 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.6 KXT05961.1 - 0.049 13.2 0.3 0.1 12.2 0.0 1.6 2 0 0 2 2 2 0 PQQ-like domain SET PF00856.28 KXT05962.1 - 4.7e-18 66.1 0.2 4.7e-18 66.1 0.2 3.6 3 1 0 3 3 3 1 SET domain SRI PF08236.11 KXT05962.1 - 4.7e-16 58.7 13.4 4.7e-16 58.7 13.4 2.2 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain AWS PF17907.1 KXT05962.1 - 5e-11 42.5 10.4 5e-11 42.5 10.4 2.2 2 0 0 2 2 2 1 AWS domain Med26 PF08711.11 KXT05962.1 - 3.1e-07 30.3 0.3 1.1e-06 28.5 0.3 2.0 1 0 0 1 1 1 1 TFIIS helical bundle-like domain WW PF00397.26 KXT05962.1 - 0.0049 16.9 3.4 0.014 15.5 3.4 1.9 1 0 0 1 1 1 1 WW domain p450 PF00067.22 KXT05963.1 - 1.5e-59 202.0 0.0 2.1e-59 201.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PrmC_N PF17827.1 KXT05964.1 - 0.00011 22.7 0.1 0.00063 20.3 0.1 2.3 1 1 0 1 1 1 1 PrmC N-terminal domain LVIVD PF08309.11 KXT05964.1 - 0.047 13.0 0.2 0.21 11.0 0.0 2.2 3 0 0 3 3 3 0 LVIVD repeat Eco57I PF07669.11 KXT05964.1 - 0.047 14.2 0.0 0.084 13.4 0.0 1.4 1 0 0 1 1 1 0 Eco57I restriction-modification methylase Methyltransf_31 PF13847.6 KXT05964.1 - 0.066 13.0 0.0 0.26 11.1 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain UPF0020 PF01170.18 KXT05964.1 - 0.21 11.3 0.2 16 5.1 0.1 2.8 2 1 1 3 3 3 0 Putative RNA methylase family UPF0020 Ribosomal_S13 PF00416.22 KXT05965.1 - 2.1e-54 183.4 2.8 2.4e-54 183.1 2.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 KXT05965.1 - 0.013 14.3 0.0 0.016 14.0 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DUF4576 PF15144.6 KXT05966.1 - 0.09 12.7 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4576) Mito_carr PF00153.27 KXT05967.1 - 3.6e-29 100.5 2.5 4.3e-15 55.4 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein NDUF_B12 PF08122.12 KXT05967.1 - 0.24 11.5 0.1 0.24 11.5 0.1 2.3 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B12 subunit family Inhibitor_I9 PF05922.16 KXT05968.1 - 0.056 14.1 0.0 0.066 13.9 0.0 1.2 1 0 0 1 1 1 0 Peptidase inhibitor I9 Phosphodiest PF01663.22 KXT05969.1 - 1.1e-13 51.6 0.6 1.8e-13 50.8 0.6 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KXT05969.1 - 9.4e-06 25.2 0.1 2.3e-05 23.9 0.1 1.7 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 KXT05969.1 - 2.7e-05 23.7 1.2 4.5e-05 22.9 1.2 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily PglZ PF08665.12 KXT05969.1 - 0.13 12.3 3.8 5.5 7.0 0.6 2.3 2 0 0 2 2 2 0 PglZ domain Gly-zipper_Omp PF13488.6 KXT05969.1 - 1.2 9.2 12.0 4.3 7.4 12.0 2.0 1 0 0 1 1 1 0 Glycine zipper Gly-zipper_YMGG PF13441.6 KXT05969.1 - 4.9 7.0 13.2 17 5.2 13.2 2.0 1 0 0 1 1 1 0 YMGG-like Gly-zipper CFEM PF05730.11 KXT05971.1 - 2e-13 50.2 9.8 2e-13 50.2 9.8 1.6 2 0 0 2 2 2 1 CFEM domain DUF5585 PF17823.1 KXT05971.1 - 4.8 6.0 9.2 0.55 9.1 0.2 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5585) CFEM PF05730.11 KXT05972.1 - 1.8e-13 50.3 9.8 1.8e-13 50.3 9.8 1.6 2 0 0 2 2 2 1 CFEM domain DUF5585 PF17823.1 KXT05972.1 - 4 6.3 9.2 0.51 9.2 0.2 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5585) CFEM PF05730.11 KXT05973.1 - 3.3e-14 52.7 9.8 4.8e-14 52.2 9.8 1.3 1 0 0 1 1 1 1 CFEM domain DUF2053 PF09767.9 KXT05974.1 - 0.05 13.8 1.7 0.085 13.0 1.1 1.5 1 1 1 2 2 2 0 Predicted membrane protein (DUF2053) DUF5585 PF17823.1 KXT05974.1 - 0.12 11.4 0.2 0.15 11.0 0.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5585) DUF3311 PF11755.8 KXT05974.1 - 0.45 10.5 3.0 14 5.7 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3311) CFEM PF05730.11 KXT05975.1 - 1.9e-13 50.3 9.8 1.9e-13 50.3 9.8 1.6 2 0 0 2 2 2 1 CFEM domain DUF5585 PF17823.1 KXT05975.1 - 4.1 6.3 9.2 0.51 9.2 0.2 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5585) CFEM PF05730.11 KXT05976.1 - 1.9e-13 50.3 9.8 1.9e-13 50.3 9.8 1.6 2 0 0 2 2 2 1 CFEM domain DUF5585 PF17823.1 KXT05976.1 - 4.1 6.3 9.2 0.51 9.2 0.2 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5585) Dynamin_N PF00350.23 KXT05977.1 - 4.2e-10 39.9 0.0 5.9e-09 36.2 0.0 2.7 1 1 1 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KXT05977.1 - 6.5e-06 26.2 0.1 0.089 12.9 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AIG1 PF04548.16 KXT05977.1 - 0.059 12.7 10.4 0.51 9.6 0.3 2.9 3 0 0 3 3 3 0 AIG1 family G-alpha PF00503.20 KXT05977.1 - 0.065 12.4 0.6 0.26 10.4 0.0 2.3 3 0 0 3 3 3 0 G-protein alpha subunit ABC_tran PF00005.27 KXT05977.1 - 0.14 12.7 1.0 2.3 8.7 0.0 3.1 3 1 0 3 3 3 0 ABC transporter UPF0184 PF03670.13 KXT05977.1 - 0.58 10.6 3.4 65 4.0 1.1 4.0 3 1 1 4 4 4 0 Uncharacterised protein family (UPF0184) DUF898 PF05987.13 KXT05978.1 - 0.0061 15.6 4.2 0.0095 15.0 0.9 2.1 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF898) NAD_binding_1 PF00175.21 KXT05978.1 - 0.01 16.5 0.0 0.018 15.7 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain CstA PF02554.14 KXT05978.1 - 0.075 11.9 4.6 0.12 11.3 4.6 1.3 1 0 0 1 1 1 0 Carbon starvation protein CstA Oxidored_q3 PF00499.20 KXT05978.1 - 0.27 11.0 3.1 0.2 11.4 1.2 1.8 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF4079 PF13301.6 KXT05978.1 - 0.46 10.6 11.4 0.21 11.7 8.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) YfhO PF09586.10 KXT05978.1 - 1.2 7.3 4.5 1.5 7.0 4.5 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Cytochrom_B561 PF03188.16 KXT05978.1 - 1.3 9.2 10.4 24 5.1 8.2 2.6 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 Dynamin_N PF00350.23 KXT05979.1 - 4.2e-10 39.9 0.0 5.9e-09 36.2 0.0 2.7 1 1 1 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KXT05979.1 - 6.5e-06 26.2 0.1 0.089 12.9 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AIG1 PF04548.16 KXT05979.1 - 0.059 12.7 10.4 0.51 9.6 0.3 2.9 3 0 0 3 3 3 0 AIG1 family G-alpha PF00503.20 KXT05979.1 - 0.065 12.4 0.6 0.26 10.4 0.0 2.3 3 0 0 3 3 3 0 G-protein alpha subunit ABC_tran PF00005.27 KXT05979.1 - 0.14 12.7 1.0 2.3 8.7 0.0 3.1 3 1 0 3 3 3 0 ABC transporter UPF0184 PF03670.13 KXT05979.1 - 0.58 10.6 3.4 65 4.0 1.1 4.0 3 1 1 4 4 4 0 Uncharacterised protein family (UPF0184) EBP PF05241.12 KXT05980.1 - 2e-54 183.7 12.0 2.6e-54 183.4 12.0 1.1 1 0 0 1 1 1 1 Emopamil binding protein Voltage_CLC PF00654.20 KXT05980.1 - 0.00024 20.5 4.9 0.00036 19.9 4.9 1.4 1 1 0 1 1 1 1 Voltage gated chloride channel QueT PF06177.11 KXT05980.1 - 0.13 12.6 6.6 0.039 14.3 1.8 2.1 1 1 1 2 2 2 0 QueT transporter Abhydrolase_3 PF07859.13 KXT05983.1 - 9.8e-56 188.9 0.0 1.5e-55 188.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold MFS_1 PF07690.16 KXT05983.1 - 9.2e-27 93.9 41.4 1.9e-25 89.6 28.8 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Say1_Mug180 PF10340.9 KXT05983.1 - 4.5e-09 35.6 0.0 6.9e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KXT05983.1 - 5.2e-05 22.8 0.0 0.0011 18.5 0.0 2.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Thioesterase PF00975.20 KXT05983.1 - 0.064 13.4 0.0 0.17 12.0 0.0 1.4 1 1 0 1 1 1 0 Thioesterase domain SBP_bac_5 PF00496.22 KXT05983.1 - 0.12 11.3 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle Cation_efflux PF01545.21 KXT05984.1 - 2e-17 63.6 2.6 2.7e-17 63.2 2.6 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KXT05984.1 - 2.2e-12 47.0 0.3 5e-12 45.8 0.3 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Vps16_N PF04841.13 KXT05985.1 - 7.9e-96 321.3 0.0 1e-95 321.0 0.0 1.1 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 KXT05985.1 - 1.5e-91 306.8 0.4 2.3e-91 306.2 0.4 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region ANAPC4_WD40 PF12894.7 KXT05985.1 - 6.5e-06 26.4 0.2 0.07 13.4 0.0 3.0 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KXT05985.1 - 0.00047 19.3 0.1 4.6 6.2 0.1 3.5 4 0 0 4 4 4 3 Coatomer WD associated region WD40 PF00400.32 KXT05985.1 - 0.14 13.1 0.2 2.5 9.1 0.1 2.6 2 0 0 2 2 2 0 WD domain, G-beta repeat Vps16_N PF04841.13 KXT05986.1 - 7.9e-96 321.3 0.0 1e-95 321.0 0.0 1.1 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 KXT05986.1 - 1.5e-91 306.8 0.4 2.3e-91 306.2 0.4 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region ANAPC4_WD40 PF12894.7 KXT05986.1 - 6.5e-06 26.4 0.2 0.07 13.4 0.0 3.0 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KXT05986.1 - 0.00047 19.3 0.1 4.6 6.2 0.1 3.5 4 0 0 4 4 4 3 Coatomer WD associated region WD40 PF00400.32 KXT05986.1 - 0.14 13.1 0.2 2.5 9.1 0.1 2.6 2 0 0 2 2 2 0 WD domain, G-beta repeat Vps16_N PF04841.13 KXT05987.1 - 7.9e-96 321.3 0.0 1e-95 321.0 0.0 1.1 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 KXT05987.1 - 1.5e-91 306.8 0.4 2.3e-91 306.2 0.4 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region ANAPC4_WD40 PF12894.7 KXT05987.1 - 6.5e-06 26.4 0.2 0.07 13.4 0.0 3.0 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KXT05987.1 - 0.00047 19.3 0.1 4.6 6.2 0.1 3.5 4 0 0 4 4 4 3 Coatomer WD associated region WD40 PF00400.32 KXT05987.1 - 0.14 13.1 0.2 2.5 9.1 0.1 2.6 2 0 0 2 2 2 0 WD domain, G-beta repeat AAA_lid_2 PF17863.1 KXT05988.1 - 0.0015 18.3 0.2 0.0061 16.4 0.1 2.0 2 0 0 2 2 2 1 AAA lid domain ADH_N PF08240.12 KXT05989.1 - 4.6e-21 74.8 0.2 7.7e-21 74.0 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain GYF PF02213.16 KXT05990.1 - 3.2e-16 58.7 1.3 7.9e-16 57.5 1.3 1.7 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 KXT05990.1 - 0.019 14.8 0.4 0.061 13.1 0.4 1.9 1 0 0 1 1 1 0 GYF domain 2 RNA_pol_Rpb2_6 PF00562.28 KXT05991.1 - 2.4e-121 405.5 0.1 3.5e-121 405.0 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KXT05991.1 - 5.6e-49 166.4 0.1 8.3e-49 165.9 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 KXT05991.1 - 3.8e-32 110.6 0.7 9.1e-32 109.3 0.7 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 KXT05991.1 - 3.4e-27 95.3 0.1 6.8e-27 94.3 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 KXT05991.1 - 5.1e-24 84.3 0.2 1.1e-23 83.3 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 KXT05991.1 - 3.5e-18 65.5 0.1 7.4e-18 64.5 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KXT05991.1 - 1.1e-09 38.7 0.5 3.8e-09 37.0 0.5 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Acyl_transf_3 PF01757.22 KXT05994.1 - 0.052 12.6 0.0 0.083 11.9 0.0 1.2 1 0 0 1 1 1 0 Acyltransferase family UCH PF00443.29 KXT05995.1 - 2.6e-38 132.0 0.2 3.1e-37 128.5 0.2 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXT05995.1 - 1.1e-07 31.8 0.7 2.4e-06 27.4 0.7 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase HRXXH PF13933.6 KXT06016.1 - 6.2e-95 317.4 0.0 7.6e-95 317.1 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Sporozoite_P67 PF05642.11 KXT06016.1 - 0.029 12.5 0.2 0.034 12.3 0.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MFS_1 PF07690.16 KXT06017.1 - 5.7e-23 81.4 83.3 5.6e-21 74.8 38.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Nudc_N PF14050.6 KXT06017.1 - 0.14 12.2 1.1 5.7 7.0 0.0 2.4 2 0 0 2 2 2 0 N-terminal conserved domain of Nudc. PAN_1 PF00024.26 KXT06018.1 - 2.9e-07 30.3 0.0 3.9e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 KXT06018.1 - 0.0013 18.6 2.1 0.0073 16.2 1.6 2.1 1 1 1 2 2 2 1 PAN domain MANEC PF07502.14 KXT06018.1 - 0.04 14.2 0.2 0.055 13.7 0.2 1.2 1 0 0 1 1 1 0 MANEC domain PAN_2 PF08276.11 KXT06018.1 - 0.056 13.6 0.4 0.072 13.2 0.4 1.3 1 0 0 1 1 1 0 PAN-like domain HJURP_C PF12347.8 KXT06020.1 - 0.014 15.4 0.1 0.045 13.8 0.1 1.8 1 0 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat Rrn6 PF10214.9 KXT06020.1 - 0.17 10.4 10.8 0.23 9.9 10.8 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF1501 PF07394.12 KXT06020.1 - 0.18 10.9 3.7 0.28 10.2 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DUF4407 PF14362.6 KXT06020.1 - 0.48 9.7 6.6 0.74 9.1 6.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Borrelia_P83 PF05262.11 KXT06020.1 - 8.9 4.7 9.6 13 4.1 9.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Esterase PF00756.20 KXT06022.1 - 3.3e-52 177.6 0.0 3.8e-52 177.4 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 KXT06022.1 - 8.2e-05 22.0 0.0 0.00018 20.9 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KXT06022.1 - 0.0022 17.5 0.0 0.0035 16.9 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 KXT06022.1 - 0.0064 16.1 0.5 0.029 13.9 0.5 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family Esterase_phd PF10503.9 KXT06022.1 - 0.013 15.0 0.0 0.13 11.7 0.0 2.0 2 0 0 2 2 2 0 Esterase PHB depolymerase Chlorophyllase2 PF12740.7 KXT06022.1 - 0.019 13.9 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_6 PF12697.7 KXT06022.1 - 0.031 14.9 0.0 0.038 14.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KXT06022.1 - 0.047 13.5 0.0 0.086 12.6 0.0 1.6 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 KXT06022.1 - 0.086 12.7 0.0 2 8.2 0.0 2.2 1 1 0 1 1 1 0 alpha/beta hydrolase fold LCAT PF02450.15 KXT06022.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase PGAP1 PF07819.13 KXT06022.1 - 0.19 11.4 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein 4HBT_3 PF13622.6 KXT06023.1 - 6.6e-34 118.3 0.0 8.9e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KXT06023.1 - 0.0018 18.1 0.1 0.18 11.7 0.0 3.3 3 1 0 3 3 3 1 Acyl-CoA thioesterase DUF5320 PF17253.2 KXT06023.1 - 0.58 11.3 3.7 0.25 12.5 0.4 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5320) BSD PF03909.17 KXT06024.1 - 2.2e-18 66.0 2.6 4.1e-18 65.1 2.6 1.5 1 0 0 1 1 1 1 BSD domain TLE_N PF03920.15 KXT06024.1 - 0.012 15.7 1.1 0.026 14.6 1.1 1.5 1 0 0 1 1 1 0 Groucho/TLE N-terminal Q-rich domain GMC_oxred_N PF00732.19 KXT06025.1 - 5.3e-53 180.3 0.0 7.6e-53 179.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase ABC2_membrane PF01061.24 KXT06025.1 - 2.2e-35 122.0 22.4 5.5e-35 120.7 22.4 1.7 1 0 0 1 1 1 1 ABC-2 type transporter GMC_oxred_C PF05199.13 KXT06025.1 - 1.1e-30 107.0 0.0 2e-30 106.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase ABC_tran PF00005.27 KXT06025.1 - 2.9e-27 95.8 0.0 5.3e-27 95.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 KXT06025.1 - 1.8e-05 24.0 14.6 1.8e-05 24.0 14.6 2.4 1 1 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 KXT06025.1 - 0.00024 21.0 0.1 0.84 9.4 0.0 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Lycopene_cycl PF05834.12 KXT06025.1 - 0.013 14.6 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KXT06025.1 - 0.015 14.5 0.0 1.7 7.8 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AAA_29 PF13555.6 KXT06025.1 - 0.02 14.6 0.0 0.046 13.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DAO PF01266.24 KXT06025.1 - 0.026 14.1 0.1 0.2 11.2 0.1 2.3 1 1 0 1 1 1 0 FAD dependent oxidoreductase Rad17 PF03215.15 KXT06025.1 - 0.066 13.1 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_25 PF13481.6 KXT06025.1 - 0.069 12.7 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain NAD_binding_8 PF13450.6 KXT06025.1 - 0.085 13.1 0.1 0.25 11.6 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain RsgA_GTPase PF03193.16 KXT06025.1 - 0.087 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 KXT06025.1 - 0.11 12.9 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 KXT06025.1 - 0.15 12.7 0.0 0.4 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KXT06025.1 - 0.21 11.7 0.0 0.44 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC2_membrane_2 PF12679.7 KXT06025.1 - 0.23 10.7 17.4 0.012 15.0 11.1 2.2 2 1 0 2 2 2 0 ABC-2 family transporter protein EGF_2 PF07974.13 KXT06025.1 - 0.92 9.9 29.1 0.38 11.2 12.6 3.7 3 0 0 3 3 3 0 EGF-like domain MFS_1 PF07690.16 KXT06026.1 - 2.3e-31 109.0 49.6 1.9e-29 102.7 29.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXT06026.1 - 4.2e-30 105.0 24.6 1.8e-23 83.2 12.1 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter BT1 PF03092.16 KXT06026.1 - 0.00046 18.6 0.4 0.00087 17.6 0.4 1.4 1 0 0 1 1 1 1 BT1 family Beta-Casp PF10996.8 KXT06026.1 - 0.034 14.4 0.1 0.067 13.5 0.1 1.4 1 0 0 1 1 1 0 Beta-Casp domain Shugoshin_N PF07558.11 KXT06027.1 - 0.21 11.5 9.5 2.9 7.8 0.1 3.5 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region Cep57_CLD_2 PF14197.6 KXT06027.1 - 1.1 9.4 11.3 0.37 10.9 3.9 2.8 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 ATG16 PF08614.11 KXT06027.1 - 1.2 9.3 18.8 0.037 14.3 6.7 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF4094 PF13334.6 KXT06027.1 - 1.3 9.5 4.5 2.1 8.8 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) Csm1_N PF18504.1 KXT06027.1 - 1.5 9.2 8.8 0.28 11.6 0.4 3.1 2 1 2 4 4 4 0 Csm1 N-terminal domain TMF_DNA_bd PF12329.8 KXT06027.1 - 5.6 7.0 14.6 0.12 12.4 2.5 3.2 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding PI3K_P85_iSH2 PF16454.5 KXT06027.1 - 6.9 6.2 11.5 0.4 10.2 3.3 2.3 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Spc7 PF08317.11 KXT06028.1 - 2e-102 342.2 5.2 4.2e-102 341.2 5.2 1.6 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc7_N PF15402.6 KXT06028.1 - 8.4e-80 269.2 95.9 5.2e-75 253.4 72.8 5.3 1 1 2 3 3 3 2 N-terminus of kinetochore NMS complex subunit Spc7 Spc7_C2 PF15577.6 KXT06028.1 - 1.1e-18 67.0 0.4 2.4e-18 65.9 0.4 1.6 1 0 0 1 1 1 1 Spc7_C2 ALIX_LYPXL_bnd PF13949.6 KXT06028.1 - 0.0048 16.2 5.5 0.0048 16.2 5.5 2.5 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV PLN_propep PF16485.5 KXT06028.1 - 0.045 13.5 0.1 0.14 11.8 0.1 1.9 1 0 0 1 1 1 0 Protealysin propeptide DUF948 PF06103.11 KXT06028.1 - 0.054 13.8 0.6 0.19 12.0 0.6 2.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DASH_Duo1 PF08651.10 KXT06028.1 - 0.35 10.7 2.2 1.3 8.8 1.6 2.4 1 1 1 2 2 2 0 DASH complex subunit Duo1 Sterol-sensing PF12349.8 KXT06029.1 - 6.6e-36 123.5 8.3 6.6e-36 123.5 8.3 2.2 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KXT06029.1 - 1.2e-10 40.2 7.1 1.8e-10 39.6 7.1 1.2 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 KXT06030.1 - 6.6e-36 123.5 8.3 6.6e-36 123.5 8.3 2.2 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KXT06030.1 - 1.2e-10 40.2 7.1 1.9e-10 39.6 7.1 1.2 1 0 0 1 1 1 1 Patched family UNC-93 PF05978.16 KXT06031.1 - 5.5e-13 48.9 8.9 5.5e-13 48.9 8.9 2.6 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 KXT06031.1 - 1.6e-08 33.9 24.7 4.6e-08 32.4 24.7 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily NMT_C PF02799.15 KXT06032.1 - 2.9e-77 258.9 0.0 4.3e-77 258.4 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 KXT06032.1 - 1e-67 226.9 0.0 1.9e-67 226.1 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 KXT06032.1 - 3.9e-07 30.2 0.0 1.6e-05 25.0 0.0 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXT06032.1 - 0.00022 21.4 0.0 0.0078 16.4 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family PGA2 PF07543.12 KXT06032.1 - 0.057 13.4 5.5 0.12 12.3 5.5 1.6 1 0 0 1 1 1 0 Protein trafficking PGA2 Rrp44_CSD1 PF17216.3 KXT06032.1 - 0.061 13.0 0.2 0.12 12.0 0.2 1.5 1 0 0 1 1 1 0 Rrp44-like cold shock domain Nop53 PF07767.11 KXT06032.1 - 0.081 12.3 10.1 0.11 11.8 10.1 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CDV3 PF15359.6 KXT06032.1 - 0.34 11.4 8.8 0.63 10.5 8.8 1.3 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 PBP1_TM PF14812.6 KXT06032.1 - 0.74 10.2 3.8 1.8 9.0 3.8 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Med3 PF11593.8 KXT06032.1 - 0.95 8.6 3.2 1.4 8.0 3.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal HSP90 PF00183.18 KXT06032.1 - 1.3 7.8 6.0 2.2 7.1 6.0 1.2 1 0 0 1 1 1 0 Hsp90 protein CDC45 PF02724.14 KXT06032.1 - 4.9 5.3 7.6 7 4.8 7.6 1.1 1 0 0 1 1 1 0 CDC45-like protein adh_short PF00106.25 KXT06033.1 - 1e-47 162.1 0.2 1.2e-47 161.9 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT06033.1 - 3.6e-39 134.7 0.4 4.2e-39 134.5 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT06033.1 - 9.6e-11 41.9 0.2 1.4e-10 41.4 0.2 1.2 1 0 0 1 1 1 1 KR domain Methyltransf_12 PF08242.12 KXT06033.1 - 5e-05 24.0 0.0 7.8e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 KXT06033.1 - 7e-05 22.4 0.0 7.9e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KXT06033.1 - 0.00037 20.4 0.0 0.00058 19.8 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KXT06033.1 - 0.00057 19.0 0.1 0.00066 18.8 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KXT06033.1 - 0.00059 19.0 0.0 0.00098 18.3 0.0 1.3 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KXT06033.1 - 0.00075 18.7 0.0 0.001 18.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Methyltransf_25 PF13649.6 KXT06033.1 - 0.0066 17.1 0.1 0.011 16.4 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KXT06033.1 - 0.018 14.8 0.1 0.027 14.2 0.1 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GDP_Man_Dehyd PF16363.5 KXT06033.1 - 0.02 14.3 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase THF_DHG_CYH_C PF02882.19 KXT06033.1 - 0.042 13.2 0.1 0.086 12.2 0.0 1.5 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.19 KXT06033.1 - 0.044 13.1 0.0 0.074 12.4 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ubie_methyltran PF01209.18 KXT06033.1 - 0.05 12.9 0.0 0.07 12.5 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family TrkA_N PF02254.18 KXT06033.1 - 0.076 13.3 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_4 PF07993.12 KXT06033.1 - 0.093 11.9 0.1 0.53 9.4 0.1 2.1 1 1 0 1 1 1 0 Male sterility protein adh_short_C2 PF13561.6 KXT06034.1 - 3.7e-06 26.7 0.1 3.7e-06 26.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short_C2 PF13561.6 KXT06035.1 - 8.9e-54 182.5 3.3 1.1e-53 182.3 3.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXT06035.1 - 8.6e-52 175.4 1.0 1.1e-51 175.1 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXT06035.1 - 1.3e-10 41.5 0.3 1.9e-10 41.0 0.3 1.3 1 0 0 1 1 1 1 KR domain Methyltransf_12 PF08242.12 KXT06035.1 - 8.6e-05 23.2 0.0 0.00014 22.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 KXT06035.1 - 0.00012 21.6 0.0 0.00015 21.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KXT06035.1 - 0.00051 20.0 0.0 0.00093 19.1 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KXT06035.1 - 0.00096 18.2 0.1 0.0012 17.9 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KXT06035.1 - 0.001 18.2 0.0 0.0018 17.5 0.0 1.3 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KXT06035.1 - 0.0012 18.1 0.0 0.0016 17.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Methyltransf_25 PF13649.6 KXT06035.1 - 0.011 16.5 0.1 0.02 15.6 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 KXT06035.1 - 0.027 14.2 0.1 0.042 13.6 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GDP_Man_Dehyd PF16363.5 KXT06035.1 - 0.03 13.7 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 2-Hacid_dh_C PF02826.19 KXT06035.1 - 0.052 12.9 0.1 0.12 11.8 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 KXT06035.1 - 0.058 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Ubie_methyltran PF01209.18 KXT06035.1 - 0.076 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family adh_short_C2 PF13561.6 KXT06036.1 - 8.9e-54 182.5 3.3 1.1e-53 182.3 3.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXT06036.1 - 8.6e-52 175.4 1.0 1.1e-51 175.1 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXT06036.1 - 1.3e-10 41.5 0.3 1.9e-10 41.0 0.3 1.3 1 0 0 1 1 1 1 KR domain Methyltransf_12 PF08242.12 KXT06036.1 - 8.6e-05 23.2 0.0 0.00014 22.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 KXT06036.1 - 0.00012 21.6 0.0 0.00015 21.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KXT06036.1 - 0.00051 20.0 0.0 0.00093 19.1 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KXT06036.1 - 0.00096 18.2 0.1 0.0012 17.9 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KXT06036.1 - 0.001 18.2 0.0 0.0018 17.5 0.0 1.3 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KXT06036.1 - 0.0012 18.1 0.0 0.0016 17.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Methyltransf_25 PF13649.6 KXT06036.1 - 0.011 16.5 0.1 0.02 15.6 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 KXT06036.1 - 0.027 14.2 0.1 0.042 13.6 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GDP_Man_Dehyd PF16363.5 KXT06036.1 - 0.03 13.7 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 2-Hacid_dh_C PF02826.19 KXT06036.1 - 0.052 12.9 0.1 0.12 11.8 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 KXT06036.1 - 0.058 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Ubie_methyltran PF01209.18 KXT06036.1 - 0.076 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family adh_short PF00106.25 KXT06037.1 - 1e-47 162.1 0.2 1.2e-47 161.9 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT06037.1 - 3.6e-39 134.7 0.4 4.2e-39 134.5 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT06037.1 - 9.6e-11 41.9 0.2 1.4e-10 41.4 0.2 1.2 1 0 0 1 1 1 1 KR domain Methyltransf_12 PF08242.12 KXT06037.1 - 5e-05 24.0 0.0 7.8e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 KXT06037.1 - 7e-05 22.4 0.0 7.9e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KXT06037.1 - 0.00037 20.4 0.0 0.00058 19.8 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KXT06037.1 - 0.00057 19.0 0.1 0.00066 18.8 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KXT06037.1 - 0.00059 19.0 0.0 0.00098 18.3 0.0 1.3 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KXT06037.1 - 0.00075 18.7 0.0 0.001 18.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Methyltransf_25 PF13649.6 KXT06037.1 - 0.0066 17.1 0.1 0.011 16.4 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KXT06037.1 - 0.018 14.8 0.1 0.027 14.2 0.1 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GDP_Man_Dehyd PF16363.5 KXT06037.1 - 0.02 14.3 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase THF_DHG_CYH_C PF02882.19 KXT06037.1 - 0.042 13.2 0.1 0.086 12.2 0.0 1.5 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.19 KXT06037.1 - 0.044 13.1 0.0 0.074 12.4 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ubie_methyltran PF01209.18 KXT06037.1 - 0.05 12.9 0.0 0.07 12.5 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family TrkA_N PF02254.18 KXT06037.1 - 0.076 13.3 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_4 PF07993.12 KXT06037.1 - 0.093 11.9 0.1 0.53 9.4 0.1 2.1 1 1 0 1 1 1 0 Male sterility protein Raf1_HTH PF18579.1 KXT06038.1 - 0.03 14.0 0.1 0.065 12.9 0.1 1.5 1 0 0 1 1 1 0 Rubisco accumulation factor 1 helix turn helix domain KELK PF15796.5 KXT06038.1 - 0.077 13.5 19.5 2.9 8.4 11.6 4.0 3 1 1 4 4 4 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase ATG16 PF08614.11 KXT06038.1 - 0.12 12.5 27.9 0.1 12.8 17.8 3.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) CENP-Q PF13094.6 KXT06038.1 - 0.23 11.6 13.7 0.062 13.5 9.9 2.1 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Laminin_I PF06008.14 KXT06038.1 - 0.42 10.3 21.1 0.017 14.9 13.0 2.4 3 0 0 3 3 3 0 Laminin Domain I Rootletin PF15035.6 KXT06038.1 - 0.5 10.4 25.3 0.046 13.7 17.7 2.4 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Uso1_p115_C PF04871.13 KXT06038.1 - 0.65 10.4 22.6 0.23 11.8 15.3 2.7 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region NPV_P10 PF05531.12 KXT06038.1 - 1 9.9 6.9 34 5.0 1.8 3.4 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein AAA_32 PF13654.6 KXT06038.1 - 1 8.0 9.0 1.9 7.2 9.0 1.3 1 0 0 1 1 1 0 AAA domain DUF4446 PF14584.6 KXT06038.1 - 1.8 8.6 5.2 4.3 7.3 4.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) DUF4201 PF13870.6 KXT06038.1 - 2 8.1 17.7 0.17 11.6 12.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) DUF4472 PF14739.6 KXT06038.1 - 2 9.2 17.7 6.2 7.6 9.2 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4472) Sec34 PF04136.15 KXT06038.1 - 2.2 8.1 16.6 2.2 8.2 0.9 2.4 2 0 0 2 2 2 0 Sec34-like family APG6_N PF17675.1 KXT06038.1 - 2.5 8.6 25.0 3.2 8.3 19.3 2.6 2 0 0 2 2 2 0 Apg6 coiled-coil region FapA PF03961.13 KXT06038.1 - 2.5 6.6 6.0 5 5.6 6.0 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A KLRAQ PF10205.9 KXT06038.1 - 3 8.1 17.7 1.5 9.1 12.2 2.8 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein LPP PF04728.13 KXT06038.1 - 3.4 8.1 5.7 69 4.0 3.0 2.9 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Laminin_II PF06009.12 KXT06038.1 - 4.7 7.2 12.7 25 4.9 7.6 2.5 2 0 0 2 2 2 0 Laminin Domain II WSC PF01822.19 KXT06039.1 - 1.3e-33 115.0 55.3 2.9e-18 65.8 16.0 5.4 4 1 1 5 5 5 3 WSC domain PAN_4 PF14295.6 KXT06039.1 - 4e-07 29.8 4.9 0.00022 21.1 0.3 4.7 5 0 0 5 5 5 2 PAN domain PAN_1 PF00024.26 KXT06039.1 - 3.7e-06 26.8 22.1 0.001 19.0 0.4 5.4 4 1 1 5 5 5 2 PAN domain PAN_3 PF08277.12 KXT06039.1 - 0.00047 19.9 23.4 0.0032 17.2 0.8 4.8 4 0 0 4 4 4 3 PAN-like domain DUF1749 PF08538.10 KXT06039.1 - 0.0054 15.9 0.0 0.009 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) OAD_gamma PF04277.13 KXT06042.1 - 0.068 13.8 0.6 0.38 11.4 0.0 2.3 1 1 1 2 2 2 0 Oxaloacetate decarboxylase, gamma chain zf-CCHC PF00098.23 KXT06043.1 - 9.3e-06 25.5 2.8 1.8e-05 24.6 2.8 1.5 1 0 0 1 1 1 1 Zinc knuckle Pectate_lyase PF03211.13 KXT06044.1 - 2.4e-87 291.8 4.2 3.3e-87 291.3 4.2 1.2 1 0 0 1 1 1 1 Pectate lyase Apt1 PF10351.9 KXT06044.1 - 0.005 15.7 4.6 0.0061 15.5 4.6 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain SPX PF03105.19 KXT06044.1 - 0.011 15.7 2.4 0.012 15.5 2.4 1.1 1 0 0 1 1 1 0 SPX domain TRAP_alpha PF03896.16 KXT06044.1 - 0.039 13.2 9.8 0.06 12.5 9.8 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Sigma70_ner PF04546.13 KXT06044.1 - 0.041 13.8 7.7 0.066 13.1 7.7 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Zip PF02535.22 KXT06044.1 - 0.042 13.1 0.7 0.065 12.4 0.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Nop14 PF04147.12 KXT06044.1 - 0.062 11.5 16.5 0.083 11.1 16.5 1.1 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.12 KXT06044.1 - 0.093 12.1 18.0 39 3.5 21.9 2.0 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT DNA_pol_phi PF04931.13 KXT06044.1 - 0.12 10.4 23.6 0.16 10.0 23.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.9 KXT06044.1 - 0.15 11.2 20.6 0.22 10.6 20.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RNA_pol_Rpc4 PF05132.14 KXT06044.1 - 0.17 12.3 4.3 0.29 11.6 4.3 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 SAPS PF04499.15 KXT06044.1 - 0.26 10.0 2.4 0.31 9.8 2.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SDA1 PF05285.12 KXT06044.1 - 0.28 10.6 18.0 0.41 10.0 18.0 1.1 1 0 0 1 1 1 0 SDA1 PTPRCAP PF15713.5 KXT06044.1 - 0.31 11.3 15.6 0.6 10.4 15.6 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated PhrC_PhrF PF11131.8 KXT06044.1 - 0.34 10.5 0.1 0.34 10.5 0.1 1.9 2 0 0 2 2 1 0 Rap-phr extracellular signalling Mpp10 PF04006.12 KXT06044.1 - 0.36 9.2 14.1 0.48 8.8 14.1 1.1 1 0 0 1 1 1 0 Mpp10 protein Tim54 PF11711.8 KXT06044.1 - 0.38 9.5 4.5 0.55 9.0 4.5 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CPSF100_C PF13299.6 KXT06044.1 - 0.69 10.1 2.6 1.7 8.8 2.6 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal PBP1_TM PF14812.6 KXT06044.1 - 0.86 10.0 15.0 1.6 9.1 15.0 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF913 PF06025.12 KXT06044.1 - 1.7 7.5 4.7 2.4 7.1 4.7 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NOA36 PF06524.12 KXT06044.1 - 2.8 7.2 23.4 5 6.4 23.4 1.3 1 0 0 1 1 1 0 NOA36 protein BUD22 PF09073.10 KXT06044.1 - 3.8 6.7 21.9 6.3 6.0 21.9 1.2 1 0 0 1 1 1 0 BUD22 Presenilin PF01080.17 KXT06044.1 - 4.4 6.0 4.5 6 5.5 4.5 1.1 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 KXT06044.1 - 5.4 5.4 6.9 7 5.1 6.9 1.1 1 0 0 1 1 1 0 Macoilin family FAM220 PF15487.6 KXT06044.1 - 8.7 5.9 8.3 13 5.3 8.3 1.1 1 0 0 1 1 1 0 FAM220 family UbiD PF01977.16 KXT06047.1 - 1.8e-107 359.8 0.0 2e-107 359.6 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Oxidored_FMN PF00724.20 KXT06050.1 - 2.2e-61 208.0 0.0 3.3e-61 207.4 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family HET PF06985.11 KXT06050.1 - 4.3e-37 127.7 0.7 7.8e-37 126.9 0.7 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Dus PF01207.17 KXT06050.1 - 0.028 13.5 0.0 0.11 11.6 0.0 1.9 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) DIOX_N PF14226.6 KXT06051.1 - 1.8e-24 86.7 0.0 2.9e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXT06051.1 - 9.8e-19 67.7 0.0 4.8e-18 65.5 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Cytochrom_C PF00034.21 KXT06052.1 - 1.8e-10 41.8 0.0 3.8e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 KXT06052.1 - 5.3e-07 29.9 1.9 3.2e-06 27.4 1.9 2.1 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 KXT06052.1 - 0.0011 18.7 0.2 0.0053 16.5 0.1 2.0 2 0 0 2 2 2 1 Cytochrome c-550 domain Glyco_hydro_63 PF03200.16 KXT06054.1 - 1.4e-06 27.4 9.1 0.00078 18.3 0.6 4.2 4 1 0 4 4 4 2 Glycosyl hydrolase family 63 C-terminal domain V-ATPase_H_N PF03224.14 KXT06055.1 - 1.3e-78 264.4 1.2 1.9e-78 263.9 1.2 1.2 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 KXT06055.1 - 7.2e-39 132.5 1.0 2.1e-37 127.8 0.0 3.0 3 0 0 3 3 3 1 V-ATPase subunit H RIX1 PF08167.12 KXT06055.1 - 0.019 14.7 6.4 0.93 9.2 0.0 3.7 3 1 1 4 4 4 0 rRNA processing/ribosome biogenesis Imm74 PF15603.6 KXT06055.1 - 0.057 13.6 1.2 1.9 8.8 0.0 2.4 2 0 0 2 2 2 0 Immunity protein 74 DUF1697 PF08002.11 KXT06055.1 - 0.15 12.5 0.0 0.67 10.4 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1697) Lys-AminoMut_A PF09043.11 KXT06055.1 - 0.16 10.4 0.1 1.8 7.0 0.1 2.0 2 0 0 2 2 2 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit HEAT PF02985.22 KXT06055.1 - 0.17 12.2 0.0 0.9 10.0 0.0 2.3 1 0 0 1 1 1 0 HEAT repeat Ribosomal_S5 PF00333.20 KXT06056.1 - 2.7e-26 91.3 1.0 2.7e-26 91.3 1.0 1.9 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 KXT06056.1 - 1.1e-23 82.5 0.0 2.1e-23 81.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 KXT06056.1 - 7.6 7.2 15.1 15 6.2 15.1 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 HET PF06985.11 KXT06057.1 - 9.6e-22 77.9 0.8 1.4e-21 77.4 0.8 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SMC_Nse1 PF07574.13 KXT06057.1 - 0.034 14.0 0.4 0.049 13.5 0.4 1.2 1 0 0 1 1 1 0 Nse1 non-SMC component of SMC5-6 complex DUF2555 PF10742.9 KXT06057.1 - 0.15 11.9 0.5 1 9.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2555) AAA PF00004.29 KXT06059.1 - 3e-17 63.3 0.0 5.1e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXT06059.1 - 0.11 12.8 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Aa_trans PF01490.18 KXT06060.1 - 2e-52 178.3 41.1 2.2e-52 178.1 41.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Fringe PF02434.16 KXT06061.1 - 8.3e-07 28.7 1.5 4e-05 23.2 0.7 2.6 2 1 0 2 2 2 1 Fringe-like DUF604 PF04646.12 KXT06061.1 - 0.0053 16.2 0.0 0.0095 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Glyco_transf_34 PF05637.12 KXT06061.1 - 0.014 15.1 0.5 0.014 15.1 0.5 2.0 2 0 0 2 2 2 0 galactosyl transferase GMA12/MNN10 family PAN_1 PF00024.26 KXT06061.1 - 0.033 14.2 0.1 0.078 13.0 0.1 1.5 1 0 0 1 1 1 0 PAN domain KdgT PF03812.13 KXT06062.1 - 4.1 6.6 4.8 5.4 6.3 4.8 1.1 1 0 0 1 1 1 0 2-keto-3-deoxygluconate permease Peptidase_M24 PF00557.24 KXT06063.1 - 1.7e-44 152.1 0.1 6.8e-44 150.1 0.0 2.0 2 0 0 2 2 2 1 Metallopeptidase family M24 NACHT PF05729.12 KXT06063.1 - 5.8e-06 26.3 0.1 1.7e-05 24.8 0.1 1.9 1 0 0 1 1 1 1 NACHT domain Creatinase_N PF01321.18 KXT06063.1 - 1.7e-05 25.5 0.0 4.9e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain AAA_16 PF13191.6 KXT06063.1 - 0.02 15.2 0.2 0.072 13.5 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain ARTD15_N PF18084.1 KXT06063.1 - 0.021 15.0 0.7 6.1 7.2 0.0 4.2 4 0 0 4 4 4 0 ARTD15 N-terminal domain KAP_NTPase PF07693.14 KXT06063.1 - 0.026 13.8 0.0 0.22 10.8 0.0 2.1 1 1 1 2 2 2 0 KAP family P-loop domain DUF87 PF01935.17 KXT06063.1 - 0.054 13.6 0.1 0.34 11.0 0.1 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain ABC_tran PF00005.27 KXT06063.1 - 0.055 14.0 0.0 0.17 12.4 0.0 1.8 1 0 0 1 1 1 0 ABC transporter ATPase_2 PF01637.18 KXT06063.1 - 0.084 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Coiled-coil_56 PF09813.9 KXT06064.1 - 2.5e-05 24.2 0.0 2.5e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 GMC_oxred_N PF00732.19 KXT06065.1 - 7.6e-05 22.2 0.0 0.00062 19.2 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KXT06065.1 - 0.0035 16.5 0.1 0.0048 16.0 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KXT06065.1 - 0.012 14.9 0.0 0.017 14.3 0.0 1.1 1 0 0 1 1 1 0 Thi4 family DAO PF01266.24 KXT06065.1 - 0.049 13.2 1.2 0.11 12.1 0.8 1.6 1 1 1 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KXT06065.1 - 0.072 12.3 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.24 KXT06065.1 - 0.08 12.0 0.2 0.1 11.7 0.2 1.1 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 KXT06065.1 - 0.13 11.1 0.1 0.17 10.7 0.1 1.1 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_2 PF07992.14 KXT06065.1 - 0.22 10.7 0.0 0.25 10.5 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXT06065.1 - 0.3 10.1 0.1 0.44 9.6 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A 4HBT_3 PF13622.6 KXT06067.1 - 1.8e-32 113.6 1.9 2.4e-32 113.1 1.9 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KXT06067.1 - 1.3e-08 34.7 0.3 1.2e-07 31.6 0.3 2.3 1 1 0 1 1 1 1 Acyl-CoA thioesterase PS-DH PF14765.6 KXT06067.1 - 0.00099 18.4 0.7 0.0021 17.3 0.7 1.6 1 1 0 1 1 1 1 Polyketide synthase dehydratase PRMT5_TIM PF17285.2 KXT06069.1 - 0.26 10.4 2.2 0.13 11.5 0.1 1.5 1 1 1 2 2 2 0 PRMT5 TIM barrel domain A_deaminase PF00962.22 KXT06070.1 - 3.2e-44 151.6 0.0 8.4e-44 150.2 0.0 1.6 1 1 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_3 PF07969.11 KXT06070.1 - 0.013 15.0 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Amidohydrolase family Amidohydro_1 PF01979.20 KXT06070.1 - 0.021 14.2 0.0 0.063 12.6 0.0 1.6 1 1 0 1 1 1 0 Amidohydrolase family Acetyltransf_CG PF14542.6 KXT06070.1 - 0.059 13.5 0.1 1.8 8.7 0.0 2.4 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Myb_DNA-bind_4 PF13837.6 KXT06073.1 - 0.0031 17.8 0.1 0.016 15.6 0.0 2.1 2 2 1 3 3 3 1 Myb/SANT-like DNA-binding domain ZapB PF06005.12 KXT06073.1 - 0.013 15.9 2.9 0.055 13.9 2.9 2.0 1 1 0 1 1 1 0 Cell division protein ZapB bZIP_2 PF07716.15 KXT06073.1 - 0.05 13.7 5.8 2 8.6 0.2 2.4 1 1 1 2 2 2 0 Basic region leucine zipper Myb_DNA-bind_6 PF13921.6 KXT06073.1 - 0.068 13.4 0.7 0.25 11.6 0.0 2.1 2 0 0 2 2 2 0 Myb-like DNA-binding domain DivIC PF04977.15 KXT06073.1 - 0.092 12.5 2.7 1.8 8.4 0.4 2.4 1 1 1 2 2 2 0 Septum formation initiator Cep57_CLD_2 PF14197.6 KXT06073.1 - 1.5 9.0 5.1 15 5.7 5.1 2.2 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 SIR2 PF02146.17 KXT06075.1 - 7.3e-24 84.6 0.0 7e-23 81.5 0.0 2.5 2 1 0 2 2 2 1 Sir2 family SGL PF08450.12 KXT06076.1 - 4.6e-07 29.7 0.0 0.0016 18.1 0.0 3.3 1 1 1 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region DUF5074 PF16819.5 KXT06076.1 - 0.00015 21.8 0.0 0.81 9.7 0.0 4.0 4 1 0 4 4 4 1 Domain of unknown function (DUF5074) Kelch_6 PF13964.6 KXT06076.1 - 0.014 15.7 0.0 25 5.3 0.0 3.6 3 0 0 3 3 3 0 Kelch motif bZIP_1 PF00170.21 KXT06079.1 - 2.4e-06 27.5 9.5 3.5e-06 27.0 9.5 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXT06079.1 - 0.00012 22.1 12.8 0.00018 21.6 12.8 1.2 1 0 0 1 1 1 1 Basic region leucine zipper DUF1465 PF07323.12 KXT06079.1 - 0.016 15.0 1.1 0.025 14.4 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) Ribosomal_S20p PF01649.18 KXT06079.1 - 0.056 14.1 3.5 0.091 13.4 3.5 1.3 1 0 0 1 1 1 0 Ribosomal protein S20 DivIC PF04977.15 KXT06079.1 - 0.18 11.6 2.4 0.23 11.3 1.7 1.5 1 1 0 1 1 1 0 Septum formation initiator Vac_ImportDeg PF09783.9 KXT06080.1 - 1.3e-27 96.6 0.0 5.8e-27 94.5 0.0 2.1 2 1 0 2 2 2 1 Vacuolar import and degradation protein Maf1 PF09174.10 KXT06080.1 - 0.065 13.4 2.6 2.3 8.3 0.2 2.5 2 0 0 2 2 2 0 Maf1 regulator Serglycin PF04360.12 KXT06080.1 - 0.22 11.5 2.3 0.55 10.2 2.3 1.6 1 0 0 1 1 1 0 Serglycin RhoGEF PF00621.20 KXT06081.1 - 8e-14 52.3 0.0 3.1e-13 50.4 0.0 1.9 2 0 0 2 2 2 1 RhoGEF domain Helo_like_N PF17111.5 KXT06081.1 - 0.007 15.8 0.2 0.007 15.8 0.2 2.5 4 1 0 4 4 4 1 Fungal N-terminal domain of STAND proteins Chalcone_2 PF16035.5 KXT06082.1 - 2.5e-73 246.2 0.0 3.5e-73 245.7 0.0 1.2 1 0 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 KXT06082.1 - 0.0019 18.3 0.1 0.0097 16.0 0.0 2.1 2 1 0 2 2 2 1 Chalcone isomerase-like UvdE PF03851.14 KXT06083.1 - 6.1e-112 373.4 0.0 8.3e-112 372.9 0.0 1.2 1 0 0 1 1 1 1 UV-endonuclease UvdE SGL PF08450.12 KXT06084.1 - 6.4e-08 32.5 0.1 0.0067 16.0 0.0 4.3 2 1 3 6 6 6 4 SMP-30/Gluconolactonase/LRE-like region Reg_prop PF07494.11 KXT06084.1 - 0.00088 19.2 3.4 1.3 9.5 0.1 4.9 6 0 0 6 6 6 1 Two component regulator propeller Glu_cyclase_2 PF05096.12 KXT06084.1 - 0.029 13.8 0.0 0.13 11.7 0.0 2.0 2 0 0 2 2 2 0 Glutamine cyclotransferase PQQ_2 PF13360.6 KXT06084.1 - 0.038 13.6 0.0 2 7.9 0.0 2.6 1 1 0 2 2 2 0 PQQ-like domain SGL PF08450.12 KXT06085.1 - 6.4e-08 32.5 0.1 0.0067 16.0 0.0 4.3 2 1 3 6 6 6 4 SMP-30/Gluconolactonase/LRE-like region Reg_prop PF07494.11 KXT06085.1 - 0.00088 19.2 3.4 1.3 9.5 0.1 4.9 6 0 0 6 6 6 1 Two component regulator propeller Glu_cyclase_2 PF05096.12 KXT06085.1 - 0.029 13.8 0.0 0.13 11.7 0.0 2.0 2 0 0 2 2 2 0 Glutamine cyclotransferase PQQ_2 PF13360.6 KXT06085.1 - 0.038 13.6 0.0 2 7.9 0.0 2.6 1 1 0 2 2 2 0 PQQ-like domain Abhydrolase_1 PF00561.20 KXT06086.1 - 1.6e-15 57.5 0.0 5.2e-15 55.8 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXT06086.1 - 1.8e-13 50.3 0.0 3e-12 46.3 0.0 2.5 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KXT06086.1 - 3.5e-11 44.1 0.0 5.2e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KXT06086.1 - 1.2e-05 24.9 0.0 0.015 14.7 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.20 KXT06086.1 - 0.017 14.8 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Thioesterase PF00975.20 KXT06086.1 - 0.02 15.0 0.0 0.037 14.1 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain DLH PF01738.18 KXT06086.1 - 0.029 13.9 0.0 7.4 6.0 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 KXT06086.1 - 0.053 13.3 0.0 12 5.6 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase PGAP1 PF07819.13 KXT06086.1 - 0.07 12.8 0.4 0.12 12.0 0.3 1.4 1 1 0 1 1 1 0 PGAP1-like protein DUF1100 PF06500.11 KXT06086.1 - 0.19 10.5 0.0 0.25 10.1 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Lipase_2 PF01674.18 KXT06086.1 - 0.21 11.1 0.0 0.49 9.9 0.0 1.5 2 0 0 2 2 2 0 Lipase (class 2) Sel1 PF08238.12 KXT06087.1 - 3.3e-37 126.1 23.8 4.9e-07 30.2 0.2 6.9 7 0 0 7 7 7 6 Sel1 repeat TPR_16 PF13432.6 KXT06087.1 - 0.00075 20.1 0.7 0.013 16.2 0.3 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXT06087.1 - 0.12 12.9 2.6 22 5.6 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KXT06087.1 - 0.61 10.4 1.9 4.6 7.5 0.3 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Topoisom_bac PF01131.20 KXT06088.1 - 1e-105 354.1 0.0 1.1e-99 334.3 0.0 2.1 2 0 0 2 2 2 2 DNA topoisomerase Toprim PF01751.22 KXT06088.1 - 1.9e-19 69.8 0.0 4.2e-19 68.7 0.0 1.6 1 0 0 1 1 1 1 Toprim domain PRR20 PF15708.5 KXT06088.1 - 0.011 15.7 4.4 0.019 14.9 4.4 1.4 1 0 0 1 1 1 0 Proline-rich protein family 20 BMFP PF04380.13 KXT06088.1 - 0.057 13.9 0.4 0.15 12.6 0.4 1.6 1 0 0 1 1 1 0 Membrane fusogenic activity Abhydrolase_6 PF12697.7 KXT06089.1 - 8.5e-18 65.8 0.1 1.1e-17 65.4 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXT06089.1 - 2.4e-07 30.7 0.0 1.3e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_8 PF06259.12 KXT06089.1 - 1.6e-06 27.9 0.1 2.4e-06 27.3 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase Ser_hydrolase PF06821.13 KXT06089.1 - 0.0019 18.1 0.4 0.013 15.3 0.1 2.2 2 1 0 2 2 2 1 Serine hydrolase DUF900 PF05990.12 KXT06089.1 - 0.0077 15.8 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Cutinase PF01083.22 KXT06089.1 - 0.012 15.5 0.0 0.028 14.4 0.0 1.5 2 0 0 2 2 2 0 Cutinase Hydrolase_4 PF12146.8 KXT06089.1 - 0.017 14.4 0.0 0.036 13.3 0.0 1.8 1 1 0 1 1 1 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 KXT06089.1 - 0.15 11.8 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein LIDHydrolase PF10230.9 KXT06089.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Arc PF03869.14 KXT06089.1 - 0.16 11.9 0.0 0.78 9.6 0.0 2.1 3 0 0 3 3 3 0 Arc-like DNA binding domain MFS_1 PF07690.16 KXT06090.1 - 2e-24 86.2 34.3 3.2e-24 85.5 30.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_2_4 PF16082.5 KXT06090.1 - 0.15 11.8 1.4 0.82 9.4 0.2 2.6 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like DUF2614 PF11023.8 KXT06090.1 - 0.18 11.9 0.7 2.4 8.3 0.0 2.6 2 0 0 2 2 2 0 Zinc-ribbon containing domain CAP_N PF01213.19 KXT06091.1 - 0.74 9.2 6.2 0.89 9.0 6.2 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Spt20 PF12090.8 KXT06091.1 - 1.5 8.3 10.1 1.9 8.0 10.1 1.2 1 0 0 1 1 1 0 Spt20 family Zip PF02535.22 KXT06092.1 - 2.1e-36 125.8 19.5 5.8e-36 124.4 19.5 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter Thyroglobulin_1 PF00086.18 KXT06092.1 - 0.0023 17.6 0.5 22 4.8 0.0 4.3 3 1 1 4 4 4 2 Thyroglobulin type-1 repeat Trypan_glycop_C PF10659.9 KXT06092.1 - 0.47 10.8 3.6 7.7 7.0 0.0 3.4 2 1 1 3 3 3 0 Trypanosome variant surface glycoprotein C-terminal domain FAD_binding_3 PF01494.19 KXT06093.1 - 3.8e-20 72.4 0.0 5.6e-20 71.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KXT06093.1 - 1.4e-07 31.4 0.3 0.017 14.7 0.8 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXT06093.1 - 3e-07 30.0 1.7 4.3e-06 26.2 1.7 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXT06093.1 - 9.6e-06 25.7 0.2 2.3e-05 24.5 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KXT06093.1 - 0.00038 19.3 4.7 0.0059 15.4 4.7 2.0 1 1 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 KXT06093.1 - 0.001 18.2 1.2 0.0017 17.5 1.2 1.3 1 1 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KXT06093.1 - 0.0013 17.9 2.4 0.0026 16.9 2.4 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KXT06093.1 - 0.0022 17.3 1.1 0.056 12.7 0.3 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXT06093.1 - 0.014 14.2 2.7 0.56 9.0 0.1 2.4 3 0 0 3 3 3 0 Tryptophan halogenase SE PF08491.10 KXT06093.1 - 0.016 14.3 0.0 0.035 13.1 0.0 1.5 2 0 0 2 2 2 0 Squalene epoxidase FAD_oxidored PF12831.7 KXT06093.1 - 0.025 13.9 1.7 0.06 12.7 1.7 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase Rossmann-like PF10727.9 KXT06093.1 - 0.027 14.3 0.2 0.047 13.5 0.2 1.3 1 0 0 1 1 1 0 Rossmann-like domain Amino_oxidase PF01593.24 KXT06093.1 - 0.03 13.6 0.3 2.9 7.1 0.0 2.7 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 KXT06093.1 - 0.15 11.3 0.4 0.35 10.1 0.4 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KXT06093.1 - 0.57 10.8 1.9 15 6.2 0.7 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AKAP7_NLS PF10469.9 KXT06094.1 - 2.2e-24 86.5 0.0 3.9e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain Epimerase PF01370.21 KXT06095.1 - 1.8e-13 50.5 0.0 7.5e-09 35.4 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXT06095.1 - 3e-09 37.0 0.0 5e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXT06095.1 - 3.8e-07 29.9 0.0 9.7e-07 28.6 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family GDP_Man_Dehyd PF16363.5 KXT06095.1 - 1e-06 28.4 0.0 1.6e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KXT06095.1 - 1.3e-06 27.7 0.0 2.5e-06 26.7 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KXT06095.1 - 0.0049 16.1 0.1 0.036 13.2 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein Sacchrp_dh_NADP PF03435.18 KXT06095.1 - 0.0063 16.8 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KXT06095.1 - 0.0065 16.9 0.0 0.011 16.1 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain GST_N_3 PF13417.6 KXT06096.1 - 8.7e-05 22.9 0.1 0.00021 21.6 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXT06096.1 - 0.059 13.4 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KXT06096.1 - 0.062 13.6 0.0 0.14 12.5 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Man-6-P_recep PF02157.15 KXT06097.1 - 5.3e-15 55.2 0.0 5.2e-14 51.9 0.0 2.0 1 1 1 2 2 2 1 Mannose-6-phosphate receptor ATG27 PF09451.10 KXT06097.1 - 5e-12 46.2 0.2 2.4e-11 44.0 0.1 1.9 2 0 0 2 2 2 1 Autophagy-related protein 27 CIMR PF00878.18 KXT06097.1 - 1e-06 28.8 0.3 0.0018 18.4 0.0 2.3 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Aminotran_5 PF00266.19 KXT06098.1 - 1.7e-94 316.9 0.0 8.4e-94 314.6 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KXT06098.1 - 6.4e-07 28.9 0.0 1.1e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KXT06098.1 - 1e-06 28.2 0.0 1.7e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KXT06098.1 - 2.8e-05 23.6 0.0 6.5e-05 22.4 0.0 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KXT06098.1 - 0.0024 16.5 0.0 0.0045 15.6 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Pyridoxal_deC PF00282.19 KXT06098.1 - 0.02 13.6 0.0 0.029 13.1 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain PhyH PF05721.13 KXT06099.1 - 6.2e-14 52.7 0.0 9.1e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) PhyH PF05721.13 KXT06102.1 - 6.2e-14 52.7 0.0 9.1e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) L51_S25_CI-B8 PF05047.16 KXT06104.1 - 2.4e-15 56.2 0.0 4.4e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain T4SS PF07996.11 KXT06104.1 - 0.016 15.7 0.4 0.022 15.2 0.4 1.3 1 0 0 1 1 1 0 Type IV secretion system proteins FAD_binding_3 PF01494.19 KXT06106.1 - 8.9e-65 219.2 0.1 1.2e-64 218.8 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KXT06106.1 - 0.00023 21.6 0.0 0.0083 16.7 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXT06106.1 - 0.00036 19.4 0.1 0.0026 16.5 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 KXT06106.1 - 0.00059 19.2 0.0 0.0083 15.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXT06106.1 - 0.00099 18.3 0.1 0.59 9.1 0.2 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KXT06106.1 - 0.0038 16.5 0.2 0.28 10.4 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXT06106.1 - 0.013 15.7 0.0 0.037 14.3 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXT06106.1 - 0.016 14.8 0.5 0.12 12.0 0.0 2.5 2 1 1 3 3 3 0 FAD dependent oxidoreductase PhageMin_Tail PF10145.9 KXT06106.1 - 0.017 15.0 0.1 0.028 14.3 0.1 1.3 1 0 0 1 1 1 0 Phage-related minor tail protein AlaDh_PNT_C PF01262.21 KXT06106.1 - 0.068 12.5 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Aldo_ket_red PF00248.21 KXT06108.1 - 4.1e-61 206.8 0.0 4.8e-61 206.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Nup54 PF13874.6 KXT06108.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DUF913 PF06025.12 KXT06108.1 - 0.21 10.5 0.0 0.29 10.1 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Aldo_ket_red PF00248.21 KXT06109.1 - 4.1e-61 206.8 0.0 4.8e-61 206.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Nup54 PF13874.6 KXT06109.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DUF913 PF06025.12 KXT06109.1 - 0.21 10.5 0.0 0.29 10.1 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Rgp1 PF08737.10 KXT06110.1 - 3.1e-144 481.2 0.0 5.8e-143 477.0 0.0 2.9 4 0 0 4 4 4 1 Rgp1 Ribosomal_S8e PF01201.22 KXT06110.1 - 3.3e-52 176.3 1.7 6.4e-52 175.4 1.7 1.5 1 0 0 1 1 1 1 Ribosomal protein S8e Arrestin_N PF00339.29 KXT06110.1 - 1.7e-06 28.2 0.0 0.00077 19.5 0.0 3.1 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KXT06110.1 - 0.00037 21.0 0.0 0.4 11.1 0.0 3.1 3 0 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Peptidase_A22B PF04258.13 KXT06111.1 - 1.9e-63 214.7 4.4 3.7e-63 213.7 4.4 1.4 1 0 0 1 1 1 1 Signal peptide peptidase VASt PF16016.5 KXT06111.1 - 7e-26 91.5 1.8 1.6e-25 90.3 1.8 1.6 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain BAR_3 PF16746.5 KXT06111.1 - 4.5e-16 59.3 0.9 8.4e-16 58.4 0.0 1.9 2 0 0 2 2 2 1 BAR domain of APPL family PH PF00169.29 KXT06111.1 - 5.5e-10 39.7 0.1 1.9e-09 38.0 0.1 2.0 1 0 0 1 1 1 1 PH domain SPP PF06550.11 KXT06111.1 - 9.7e-08 31.8 1.4 9.7e-08 31.8 1.4 2.1 2 0 0 2 2 2 1 Signal-peptide peptidase, presenilin aspartyl protease GRAM PF02893.20 KXT06111.1 - 0.042 13.7 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 GRAM domain DUF1517 PF07466.11 KXT06111.1 - 3.8 7.6 6.1 0.41 10.8 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1517) Curto_V3 PF07436.11 KXT06112.1 - 0.036 14.4 1.4 0.34 11.3 0.4 2.6 2 0 0 2 2 2 0 Curtovirus V3 protein Cupin_2 PF07883.11 KXT06113.1 - 1.3e-07 31.2 0.9 2.8e-07 30.1 0.2 1.9 1 1 1 2 2 2 1 Cupin domain Cupin_1 PF00190.22 KXT06113.1 - 0.087 12.4 0.0 0.16 11.6 0.0 1.5 1 1 0 1 1 1 0 Cupin TolB_like PF15869.5 KXT06116.1 - 0.22 10.7 0.0 0.29 10.3 0.0 1.1 1 0 0 1 1 1 0 TolB-like 6-blade propeller-like Diphthamide_syn PF01866.17 KXT06117.1 - 2.3e-116 388.5 0.0 2.8e-116 388.2 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein MFS_1 PF07690.16 KXT06118.1 - 2.9e-22 79.1 57.4 1.4e-14 53.8 23.9 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Pterin_4a PF01329.19 KXT06119.1 - 0.092 12.9 0.2 0.22 11.7 0.2 1.6 1 0 0 1 1 1 0 Pterin 4 alpha carbinolamine dehydratase Peptidase_C97 PF05903.14 KXT06120.1 - 8.2e-34 116.6 0.0 1.1e-33 116.2 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 KXT06120.1 - 0.0062 16.9 0.0 0.011 16.1 0.0 1.3 1 0 0 1 1 1 1 Lecithin retinol acyltransferase DUF778 PF05608.12 KXT06120.1 - 0.046 14.1 0.0 0.08 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF778) Fez1 PF06818.15 KXT06121.1 - 0.00069 20.1 6.7 0.00069 20.1 6.7 3.2 4 0 0 4 4 4 2 Fez1 HemX PF04375.14 KXT06121.1 - 0.01 15.1 0.5 0.01 15.1 0.5 2.6 3 0 0 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase DASH_Dad4 PF08650.10 KXT06121.1 - 0.043 13.8 0.5 0.11 12.5 0.2 1.7 1 1 1 2 2 2 0 DASH complex subunit Dad4 AhpC-TSA PF00578.21 KXT06121.1 - 0.073 13.0 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 AhpC/TSA family SurA_N_3 PF13624.6 KXT06121.1 - 0.25 11.1 0.0 0.25 11.1 0.0 3.3 4 0 0 4 4 4 0 SurA N-terminal domain OrfB_IS605 PF01385.19 KXT06121.1 - 0.39 11.0 10.8 0.26 11.5 4.8 2.5 2 0 0 2 2 2 0 Probable transposase Prominin PF05478.11 KXT06121.1 - 1 7.2 2.5 3.2 5.6 0.0 2.0 1 1 1 2 2 2 0 Prominin DUF745 PF05335.13 KXT06121.1 - 1.3 8.7 16.4 0.02 14.6 6.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF745) adh_short PF00106.25 KXT06123.1 - 3e-16 59.5 0.0 3.9e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT06123.1 - 1.5e-11 44.3 0.0 1.9e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N PF00107.26 KXT06124.1 - 1.2e-21 77.0 0.9 2.5e-21 76.0 0.9 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXT06124.1 - 1.4e-09 39.1 0.1 6.1e-09 37.0 0.0 1.9 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXT06124.1 - 5.9e-05 22.9 0.0 0.00065 19.6 0.0 2.5 1 1 2 3 3 3 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 KXT06124.1 - 0.017 14.6 0.7 0.027 13.9 0.7 1.3 1 0 0 1 1 1 0 short chain dehydrogenase LDcluster4 PF18306.1 KXT06124.1 - 0.02 14.5 2.8 0.046 13.3 2.0 1.9 1 1 1 2 2 2 0 SLOG cluster4 family Spt5-NGN PF03439.13 KXT06125.1 - 2.9e-19 68.7 0.0 5.6e-19 67.8 0.0 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 KXT06125.1 - 5.5e-19 69.0 12.2 5.5e-19 69.0 12.2 4.0 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.29 KXT06125.1 - 5e-07 29.4 24.7 0.037 14.0 2.7 6.1 6 0 0 6 6 6 3 KOW motif CTD PF12815.7 KXT06125.1 - 0.00016 22.2 41.6 0.014 16.0 14.1 3.7 1 1 1 2 2 2 2 Spt5 C-terminal nonapeptide repeat binding Spt4 DUF3912 PF13051.6 KXT06125.1 - 0.055 13.7 2.2 1.2 9.4 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3912) DUF150_C PF17384.2 KXT06125.1 - 0.53 10.5 2.4 1.9 8.7 0.3 2.4 2 0 0 2 2 2 0 RimP C-terminal SH3 domain YajC PF02699.15 KXT06125.1 - 2.2 8.2 3.8 1.3 8.9 0.2 2.5 3 0 0 3 3 3 0 Preprotein translocase subunit Rhodanese PF00581.20 KXT06126.1 - 1.3e-19 70.7 0.0 5.4e-11 43.0 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain DUF1967 PF09269.11 KXT06126.1 - 0.045 13.7 0.1 1.2 9.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) Brix PF04427.18 KXT06127.1 - 0.0054 16.9 1.2 0.0074 16.4 1.2 1.3 1 0 0 1 1 1 1 Brix domain FAM76 PF16046.5 KXT06128.1 - 0.0035 16.8 6.1 0.0035 16.8 6.1 1.8 2 0 0 2 2 2 1 FAM76 protein FlaC_arch PF05377.11 KXT06128.1 - 0.079 13.4 4.1 1.2 9.6 0.2 2.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) EST1 PF10374.9 KXT06128.1 - 1.6 9.3 8.5 1.2 9.8 3.3 2.8 2 1 0 2 2 2 0 Telomerase activating protein Est1 Exonuc_VII_L PF02601.15 KXT06128.1 - 3.4 7.1 18.5 0.041 13.4 8.5 2.5 3 0 0 3 3 3 0 Exonuclease VII, large subunit Prefoldin PF02996.17 KXT06128.1 - 3.6 7.5 13.1 0.11 12.5 1.1 3.2 1 1 2 3 3 3 0 Prefoldin subunit Tho2 PF11262.8 KXT06128.1 - 3.9 6.6 8.8 10 5.2 8.8 1.7 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF2730 PF10805.8 KXT06128.1 - 4.3 7.5 6.3 27 4.9 3.5 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Syntaxin-6_N PF09177.11 KXT06128.1 - 5.1 7.7 25.7 3.1 8.4 9.5 4.3 3 1 1 4 4 4 0 Syntaxin 6, N-terminal DUF4407 PF14362.6 KXT06128.1 - 6.3 6.1 27.0 0.06 12.7 13.6 3.0 3 1 1 4 4 4 0 Domain of unknown function (DUF4407) Spore_III_AB PF09548.10 KXT06128.1 - 7.9 6.6 10.5 38 4.3 10.5 2.2 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) zf-ANAPC11 PF12861.7 KXT06131.1 - 2.9e-41 139.4 8.1 4.3e-41 138.9 8.1 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KXT06131.1 - 4.3e-21 75.0 14.2 7.3e-21 74.2 14.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KXT06131.1 - 1.7e-07 31.4 17.6 8.8e-07 29.2 17.6 2.0 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KXT06131.1 - 0.0011 19.0 10.9 0.023 14.7 11.6 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KXT06131.1 - 0.0021 17.9 12.3 0.0046 16.8 12.3 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KXT06131.1 - 0.0064 16.3 8.9 0.0064 16.3 8.9 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXT06131.1 - 0.025 14.5 16.0 0.24 11.4 16.7 2.1 1 1 1 2 2 2 0 zinc-RING finger domain Rad50_zn_hook PF04423.14 KXT06131.1 - 0.068 13.0 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 Rad50 zinc hook motif Zn_ribbon_17 PF17120.5 KXT06131.1 - 0.1 12.2 14.4 0.62 9.7 14.4 2.0 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 KXT06131.1 - 0.1 12.5 14.2 3 7.8 14.4 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 KXT06131.1 - 0.18 12.0 13.2 0.97 9.7 13.2 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 KXT06131.1 - 1.9 8.4 13.2 4 7.3 10.1 2.5 1 1 2 3 3 3 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 KXT06131.1 - 5 7.1 9.8 10 6.0 9.8 1.6 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_11 PF17123.5 KXT06131.1 - 7.8 6.3 20.4 9.3 6.1 17.0 2.5 2 1 0 2 2 2 0 RING-like zinc finger zf-HC5HC2H_2 PF13832.6 KXT06131.1 - 9 6.5 12.9 2.4 8.4 8.9 2.0 1 1 1 2 2 2 0 PHD-zinc-finger like domain HmuY PF14064.6 KXT06132.1 - 0.074 13.3 0.0 0.088 13.0 0.0 1.3 1 0 0 1 1 1 0 HmuY protein Flavoprotein PF02441.19 KXT06133.1 - 1.9e-25 89.4 0.0 2.5e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein Gin PF10764.9 KXT06134.1 - 0.0034 17.3 0.5 0.87 9.6 0.1 2.2 2 0 0 2 2 2 2 Inhibitor of sigma-G Gin DZR PF12773.7 KXT06134.1 - 0.051 13.6 0.0 0.1 12.7 0.0 1.5 1 1 0 1 1 1 0 Double zinc ribbon Aldedh PF00171.22 KXT06135.1 - 1.2e-45 155.9 0.4 1.5e-45 155.5 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family EVE PF01878.18 KXT06136.1 - 1.7e-37 128.6 0.2 3.3e-37 127.7 0.2 1.5 1 0 0 1 1 1 1 EVE domain CDC27 PF09507.10 KXT06136.1 - 0.0039 16.6 26.1 0.0039 16.6 26.1 2.5 3 0 0 3 3 3 1 DNA polymerase subunit Cdc27 adh_short PF00106.25 KXT06139.1 - 2.9e-27 95.4 0.0 5.9e-27 94.4 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT06139.1 - 2.2e-21 76.5 0.0 4.4e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Stc1 PF12898.7 KXT06139.1 - 7.1e-20 71.3 11.4 1.7e-19 70.1 11.4 1.7 1 0 0 1 1 1 1 Stc1 domain Epimerase PF01370.21 KXT06139.1 - 3.1e-05 23.6 0.0 6e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family zf-CHY PF05495.12 KXT06139.1 - 0.0016 18.9 2.4 0.0049 17.3 2.4 1.9 1 1 0 1 1 1 1 CHY zinc finger NAD_binding_10 PF13460.6 KXT06139.1 - 0.0032 17.4 0.0 0.014 15.3 0.0 2.2 1 1 0 1 1 1 1 NAD(P)H-binding His_Me_b4a2 PF18275.1 KXT06139.1 - 0.072 13.2 3.8 0.21 11.7 0.1 2.7 2 0 0 2 2 2 0 His-Me finger endonuclease beta4-alpha2 domain 6PF2K PF01591.18 KXT06141.1 - 1e-78 263.7 0.1 1.3e-78 263.3 0.1 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KXT06141.1 - 2.6e-35 121.9 0.0 5.7e-35 120.8 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KXT06141.1 - 0.00022 21.4 0.1 0.00048 20.3 0.1 1.7 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 KXT06141.1 - 0.005 16.3 0.0 0.011 15.2 0.0 1.4 1 1 0 1 1 1 1 Chromatin associated protein KTI12 DUF816 PF05674.12 KXT06141.1 - 0.05 13.5 0.5 0.09 12.7 0.5 1.3 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF816) DUF4248 PF14053.6 KXT06141.1 - 0.075 13.1 0.0 0.83 9.7 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4248) SF3A2 PF16835.5 KXT06143.1 - 1.6e-38 131.0 0.1 2.4e-38 130.4 0.1 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 KXT06143.1 - 1.1e-05 25.7 0.5 2e-05 24.8 0.5 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type PRP4 PF08799.11 KXT06143.1 - 0.053 13.1 1.5 0.11 12.1 1.5 1.6 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Chorismate_bind PF00425.18 KXT06145.1 - 3.7e-87 292.2 0.0 5.6e-87 291.5 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 KXT06145.1 - 2.6e-29 102.2 0.0 2.7e-25 89.2 0.0 3.4 3 0 0 3 3 3 2 Anthranilate synthase component I, N terminal region NAPRTase_C PF17956.1 KXT06145.1 - 0.045 14.2 0.3 0.16 12.4 0.3 1.9 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase C-terminal domain Ribosomal_L28 PF00830.19 KXT06147.1 - 7.9e-21 74.0 2.5 2e-20 72.7 2.5 1.8 1 0 0 1 1 1 1 Ribosomal L28 family SLATT_5 PF18160.1 KXT06147.1 - 1.8 7.9 3.9 13 5.1 0.2 2.3 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 GET2 PF08690.10 KXT06148.1 - 2e-28 100.0 0.0 2.6e-28 99.6 0.0 1.1 1 0 0 1 1 1 1 GET complex subunit GET2 Pex19 PF04614.12 KXT06148.1 - 0.05 13.4 5.6 0.087 12.6 5.1 1.7 1 1 0 1 1 1 0 Pex19 protein family BAR PF03114.18 KXT06149.1 - 4.3e-60 203.3 8.4 5.4e-60 203.0 8.4 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 KXT06149.1 - 5.3e-14 51.6 0.4 1.1e-13 50.6 0.4 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXT06149.1 - 2.6e-08 33.6 0.3 1.2e-07 31.5 0.1 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KXT06149.1 - 1.2e-06 28.1 0.1 3.4e-06 26.6 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain Dscam_C PF12355.8 KXT06149.1 - 0.0052 17.7 1.2 0.009 17.0 1.2 1.4 1 0 0 1 1 1 1 Down syndrome cell adhesion molecule C terminal BRE1 PF08647.11 KXT06149.1 - 0.29 11.2 11.8 1.3 9.1 0.2 2.6 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase APG6_N PF17675.1 KXT06149.1 - 2.7 8.5 13.1 13 6.3 7.6 2.5 2 0 0 2 2 2 0 Apg6 coiled-coil region SKN1 PF03935.15 KXT06150.1 - 1.6e-223 742.6 0.7 1.9e-223 742.4 0.7 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) DIT1_PvcA PF05141.12 KXT06151.1 - 7.4e-97 324.1 0.0 9.4e-97 323.8 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein TauD PF02668.16 KXT06151.1 - 3e-22 79.7 0.1 5.2e-22 78.9 0.1 1.4 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DIT1_PvcA PF05141.12 KXT06152.1 - 7.4e-97 324.1 0.0 9.4e-97 323.8 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein TauD PF02668.16 KXT06152.1 - 3e-22 79.7 0.1 5.2e-22 78.9 0.1 1.4 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF5332 PF17266.2 KXT06153.1 - 0.0012 18.5 1.0 0.0014 18.3 1.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5332) TrbC_Ftype PF09673.10 KXT06156.1 - 0.076 13.1 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein HET PF06985.11 KXT06158.1 - 1.3e-34 119.7 0.0 2.7e-34 118.6 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyoxalase_3 PF13468.6 KXT06162.1 - 1.8e-25 90.1 0.0 2.9e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain PMBR PF09373.10 KXT06165.1 - 0.14 12.4 0.0 0.34 11.1 0.0 1.7 1 0 0 1 1 1 0 Pseudomurein-binding repeat ADH_N PF08240.12 KXT06168.1 - 3.9e-05 23.5 0.0 7.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXT06168.1 - 0.00013 21.9 0.0 0.00024 21.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase IBR PF01485.21 KXT06169.1 - 5.9e-07 29.6 49.8 0.0028 17.9 0.4 5.7 5 1 0 5 5 5 4 IBR domain, a half RING-finger domain Bromodomain PF00439.25 KXT06169.1 - 4.9e-06 26.5 0.0 9.5e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Bromodomain HIG_1_N PF04588.13 KXT06170.1 - 1.1e-21 76.7 0.0 1.7e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF4485 PF14846.6 KXT06170.1 - 0.0023 17.9 1.3 0.0047 17.0 1.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4485) TPX2 PF06886.11 KXT06170.1 - 0.013 15.8 13.1 0.013 15.8 13.1 2.5 1 1 1 2 2 2 0 Targeting protein for Xklp2 (TPX2) IATP PF04568.12 KXT06170.1 - 8.4 6.9 14.0 14 6.2 0.7 2.4 1 1 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP Fungal_trans PF04082.18 KXT06171.1 - 1.2e-26 93.3 0.0 2.4e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT06171.1 - 3.7e-09 36.6 8.3 7e-09 35.7 8.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2749 PF10907.8 KXT06171.1 - 0.18 12.0 0.1 0.54 10.5 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) Nefa_Nip30_N PF10187.9 KXT06172.1 - 1e-26 93.3 7.1 1e-26 93.3 7.1 2.6 2 1 1 3 3 3 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF572 PF04502.13 KXT06172.1 - 0.14 11.7 18.8 0.19 11.3 18.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) SOAR PF16533.5 KXT06172.1 - 1.8 8.6 12.2 0.48 10.4 2.3 2.7 2 1 1 3 3 3 0 STIM1 Orai1-activating region Ribosomal_L7Ae PF01248.26 KXT06173.1 - 6.1e-27 93.2 1.0 8.2e-27 92.8 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Glyco_hydro_31 PF01055.26 KXT06174.1 - 3.6e-86 290.1 0.0 4.6e-86 289.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KXT06174.1 - 1.6e-10 41.1 0.0 5.3e-10 39.5 0.0 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like Abhydrolase_3 PF07859.13 KXT06175.1 - 1.5e-10 41.3 0.0 1.8e-09 37.8 0.0 2.5 3 0 0 3 3 3 1 alpha/beta hydrolase fold MSP1a PF11670.8 KXT06178.1 - 0.13 11.5 0.9 0.22 10.8 0.9 1.3 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) MSP1a PF11670.8 KXT06179.1 - 0.13 11.5 0.9 0.22 10.8 0.9 1.3 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) Methyltransf_23 PF13489.6 KXT06180.1 - 0.11 12.3 0.0 0.19 11.6 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KXT06180.1 - 0.18 12.5 0.1 0.31 11.8 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KXT06181.1 - 0.11 12.3 0.0 0.19 11.6 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KXT06181.1 - 0.18 12.5 0.1 0.31 11.8 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase domain FMO-like PF00743.19 KXT06182.1 - 5.7e-16 58.0 0.0 1.9e-11 43.1 0.0 3.1 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KXT06182.1 - 1.6e-07 30.9 0.0 3.8e-07 29.7 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXT06182.1 - 3.5e-07 29.8 0.5 1.4e-05 24.5 0.4 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXT06182.1 - 8.4e-07 29.1 0.0 8.4e-07 29.1 0.0 2.2 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KXT06182.1 - 7.8e-06 25.3 0.1 0.00025 20.3 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KXT06182.1 - 0.00031 20.7 0.1 0.0011 19.0 0.1 2.1 1 1 0 1 1 1 1 FAD-NAD(P)-binding Thi4 PF01946.17 KXT06182.1 - 0.00043 19.6 1.2 0.00079 18.7 0.3 1.9 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 KXT06182.1 - 0.0019 17.5 0.1 0.0035 16.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KXT06182.1 - 0.0072 15.1 0.5 0.0072 15.1 0.5 1.5 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 KXT06182.1 - 0.017 15.7 0.0 2 9.0 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 KXT06182.1 - 0.022 13.6 0.0 0.032 13.0 0.0 1.2 1 0 0 1 1 1 0 MCRA family DAO PF01266.24 KXT06182.1 - 0.035 13.7 0.0 0.34 10.4 0.0 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KXT06182.1 - 0.038 13.3 0.0 0.083 12.2 0.0 1.5 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 KXT06182.1 - 0.039 13.0 0.1 0.096 11.8 0.1 1.6 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 KXT06182.1 - 0.35 10.2 2.1 0.53 9.6 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Ank_2 PF12796.7 KXT06184.1 - 2.3e-17 63.4 0.1 1.2e-07 32.2 0.1 4.2 2 1 2 4 4 4 2 Ankyrin repeats (3 copies) NACHT PF05729.12 KXT06184.1 - 4.2e-12 46.3 0.1 1.2e-11 44.8 0.1 1.8 1 0 0 1 1 1 1 NACHT domain Ank PF00023.30 KXT06184.1 - 1.6e-10 41.0 1.6 0.018 15.5 0.0 5.7 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 KXT06184.1 - 1.1e-08 35.5 2.9 0.0069 16.9 0.1 5.0 3 1 4 7 7 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXT06184.1 - 1.8e-08 34.0 0.3 1.1 10.0 0.0 6.5 7 0 0 7 7 6 2 Ankyrin repeat Ank_5 PF13857.6 KXT06184.1 - 1.2e-07 31.9 0.0 0.0022 18.3 0.0 5.0 4 1 1 5 5 5 1 Ankyrin repeats (many copies) AAA_16 PF13191.6 KXT06184.1 - 1.3e-06 29.0 0.1 5.2e-06 26.9 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXT06184.1 - 0.00012 22.4 0.0 0.00042 20.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 KXT06184.1 - 0.024 14.3 0.0 0.12 12.1 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF2075 PF09848.9 KXT06184.1 - 0.045 13.0 0.1 0.16 11.2 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 KXT06184.1 - 0.11 12.9 0.0 0.28 11.6 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 KXT06184.1 - 0.12 11.6 0.0 0.32 10.2 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin zf-C2H2 PF00096.26 KXT06185.1 - 1.3e-21 75.8 50.5 7.8e-05 22.9 0.4 11.0 11 1 0 11 11 11 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXT06185.1 - 4.5e-16 58.2 45.4 0.025 15.4 0.3 11.1 11 1 0 11 11 11 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXT06185.1 - 1.4e-11 44.2 41.3 0.00028 21.2 0.1 9.8 10 0 0 10 10 10 4 Zinc-finger double domain FOXP-CC PF16159.5 KXT06185.1 - 0.00014 22.4 21.0 0.0016 19.0 0.4 6.5 5 2 2 7 7 7 1 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 KXT06185.1 - 0.0017 18.6 12.2 0.11 12.8 1.0 5.0 4 1 2 6 6 6 2 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 KXT06185.1 - 0.0018 18.5 10.1 2.3 8.4 0.1 4.6 3 1 1 4 4 4 2 Aberrant zinc-finger zf_C2H2_ZHX PF18387.1 KXT06185.1 - 0.0019 17.8 17.6 3 7.6 0.1 6.8 4 2 3 7 7 7 1 Zinc-fingers and homeoboxes C2H2 finger domain zf-met PF12874.7 KXT06185.1 - 0.0062 16.9 10.5 8.5 6.9 0.2 7.2 8 0 0 8 8 8 1 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KXT06185.1 - 0.066 13.0 22.4 0.099 12.4 0.4 6.0 7 0 0 7 7 7 0 zinc-finger C2H2-type zf-C2H2_9 PF16293.5 KXT06185.1 - 0.088 12.7 1.5 2.4 8.0 0.2 3.5 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-C2H2_jaz PF12171.8 KXT06185.1 - 1.9 8.9 20.9 7.2 7.0 0.1 7.4 9 0 0 9 9 9 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KXT06185.1 - 5.9 7.3 14.6 6.8 7.1 0.4 4.7 3 1 1 4 4 4 0 C2H2 type zinc-finger (2 copies) Fungal_trans_2 PF11951.8 KXT06186.1 - 8.4e-33 113.7 7.0 1.1e-32 113.4 7.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DNA_pol3_delta2 PF13177.6 KXT06188.1 - 3.3e-11 43.2 0.1 7.7e-11 42.0 0.1 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 KXT06188.1 - 5.9e-06 26.7 0.1 1.5e-05 25.5 0.1 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 KXT06188.1 - 6.7e-06 26.4 0.3 2.1e-05 24.8 0.0 1.9 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA_22 PF13401.6 KXT06188.1 - 0.00011 22.5 0.1 0.0007 19.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KXT06188.1 - 0.00075 19.9 1.2 0.011 16.2 0.4 2.8 2 2 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 KXT06188.1 - 0.0032 17.2 0.8 0.011 15.5 0.8 1.8 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KXT06188.1 - 0.005 17.4 0.1 0.013 16.1 0.1 1.8 1 1 0 1 1 1 1 ABC transporter Rad17 PF03215.15 KXT06188.1 - 0.0059 16.6 0.0 0.018 15.0 0.0 1.7 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_23 PF13476.6 KXT06188.1 - 0.024 15.1 0.0 0.033 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KXT06188.1 - 0.047 13.4 0.0 0.28 10.9 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_5 PF07728.14 KXT06188.1 - 0.068 13.2 0.2 0.2 11.6 0.2 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Phyto-Amp PF15438.6 KXT06188.1 - 0.081 12.8 0.2 0.13 12.1 0.2 1.2 1 0 0 1 1 1 0 Antigenic membrane protein of phytoplasma DNA_pol3_delta2 PF13177.6 KXT06190.1 - 3.3e-11 43.2 0.1 7.7e-11 42.0 0.1 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 KXT06190.1 - 5.9e-06 26.7 0.1 1.5e-05 25.5 0.1 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 KXT06190.1 - 6.7e-06 26.4 0.3 2.1e-05 24.8 0.0 1.9 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA_22 PF13401.6 KXT06190.1 - 0.00011 22.5 0.1 0.0007 19.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KXT06190.1 - 0.00075 19.9 1.2 0.011 16.2 0.4 2.8 2 2 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 KXT06190.1 - 0.0032 17.2 0.8 0.011 15.5 0.8 1.8 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KXT06190.1 - 0.005 17.4 0.1 0.013 16.1 0.1 1.8 1 1 0 1 1 1 1 ABC transporter Rad17 PF03215.15 KXT06190.1 - 0.0059 16.6 0.0 0.018 15.0 0.0 1.7 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_23 PF13476.6 KXT06190.1 - 0.024 15.1 0.0 0.033 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KXT06190.1 - 0.047 13.4 0.0 0.28 10.9 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_5 PF07728.14 KXT06190.1 - 0.068 13.2 0.2 0.2 11.6 0.2 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Phyto-Amp PF15438.6 KXT06190.1 - 0.081 12.8 0.2 0.13 12.1 0.2 1.2 1 0 0 1 1 1 0 Antigenic membrane protein of phytoplasma DUF3638 PF12340.8 KXT06191.1 - 5.6e-100 333.3 2.0 1.9e-99 331.6 2.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 KXT06191.1 - 2.5e-18 65.1 1.2 5.4e-18 64.1 1.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) HMGL-like PF00682.19 KXT06192.1 - 5.2e-35 121.3 0.0 3.5e-24 85.8 0.0 2.0 2 0 0 2 2 2 2 HMGL-like CAP_N PF01213.19 KXT06192.1 - 0.14 11.6 1.9 0.2 11.1 1.9 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal TRP PF06011.12 KXT06193.1 - 5.3e-128 427.4 14.1 6.6e-128 427.1 14.1 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KXT06193.1 - 1.2e-37 129.4 0.4 2e-37 128.6 0.4 1.4 1 0 0 1 1 1 1 ML-like domain adh_short PF00106.25 KXT06194.1 - 1.3e-26 93.3 0.0 1.9e-26 92.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT06194.1 - 3.3e-16 59.6 0.0 6.6e-16 58.6 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT06194.1 - 1e-05 25.6 0.0 1.6e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXT06194.1 - 0.00064 19.2 0.1 0.0011 18.4 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Oxidored_nitro PF00148.19 KXT06194.1 - 0.0013 17.5 0.0 0.002 17.0 0.0 1.2 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase AdoHcyase_NAD PF00670.21 KXT06194.1 - 0.0036 17.4 0.2 0.0065 16.5 0.2 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Polysacc_synt_2 PF02719.15 KXT06194.1 - 0.0039 16.4 0.1 0.0051 16.0 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KXT06194.1 - 0.006 15.6 0.2 0.0077 15.3 0.2 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Urocanase PF01175.18 KXT06194.1 - 0.057 13.0 0.2 0.097 12.3 0.2 1.3 1 0 0 1 1 1 0 Urocanase Rossmann-like domain DUF2325 PF10087.9 KXT06194.1 - 0.21 11.7 0.1 0.4 10.8 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) GDP_Man_Dehyd PF16363.5 KXT06194.1 - 0.22 10.9 0.1 0.44 9.9 0.0 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase AAA_16 PF13191.6 KXT06195.1 - 3.4e-08 34.1 0.1 1.3e-07 32.1 0.1 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KXT06195.1 - 0.0057 16.4 0.3 0.014 15.1 0.0 1.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 KXT06195.1 - 0.0084 15.7 0.0 0.032 13.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KXT06195.1 - 0.022 14.3 0.0 0.082 12.4 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 KXT06195.1 - 0.23 11.3 0.2 1.9 8.4 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase DUF3328 PF11807.8 KXT06196.1 - 3.6e-25 89.0 4.1 1.1e-24 87.5 4.1 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) CorA PF01544.18 KXT06197.1 - 4e-28 98.6 10.1 3.6e-26 92.1 10.1 2.8 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein GTP_EFTU PF00009.27 KXT06198.1 - 6.1e-57 192.3 0.3 1.1e-56 191.5 0.3 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 KXT06198.1 - 1.1e-32 112.0 0.0 2.1e-32 111.0 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 KXT06198.1 - 1.1e-31 109.2 0.0 2.1e-31 108.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 KXT06198.1 - 9.3e-24 83.3 0.0 4.1e-23 81.2 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KXT06198.1 - 3.6e-14 52.9 0.2 1.3e-13 51.1 0.2 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KXT06198.1 - 2.5e-06 27.3 0.0 6.3e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 KXT06198.1 - 0.0017 18.5 0.0 0.0041 17.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gpr1_Fun34_YaaH PF01184.19 KXT06199.1 - 1.4e-59 201.2 12.4 1.1e-31 110.1 6.3 2.0 1 1 1 2 2 2 2 GPR1/FUN34/yaaH family FeoB_associated PF12669.7 KXT06200.1 - 0.0062 16.9 1.1 0.011 16.1 1.1 1.4 1 0 0 1 1 1 1 FeoB-associated Cys-rich membrane protein AJAP1_PANP_C PF15298.6 KXT06200.1 - 0.11 12.7 10.4 0.05 13.8 7.9 1.7 1 1 1 2 2 2 0 AJAP1/PANP C-terminus TMEM154 PF15102.6 KXT06200.1 - 0.18 11.7 2.0 0.59 10.0 2.0 1.9 1 1 0 1 1 1 0 TMEM154 protein family DUF2207 PF09972.9 KXT06200.1 - 0.21 10.3 0.0 0.31 9.8 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SCF PF02404.15 KXT06200.1 - 2.8 7.2 4.6 0.54 9.6 0.9 1.6 2 0 0 2 2 2 0 Stem cell factor MCC-bdg_PDZ PF10506.9 KXT06203.1 - 0.89 9.6 9.3 1.2 9.2 0.3 4.1 4 0 0 4 4 4 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Fib_alpha PF08702.10 KXT06203.1 - 10 6.3 21.8 9 6.5 0.1 3.0 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family adh_short PF00106.25 KXT06205.1 - 1.3e-39 135.7 0.7 2.8e-39 134.6 0.7 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT06205.1 - 3.3e-25 89.0 0.2 5.9e-25 88.2 0.2 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KXT06205.1 - 2.2e-07 30.6 0.0 1.7e-05 24.4 0.0 2.3 2 1 0 2 2 2 2 Fungal family of unknown function (DUF1776) DUF521 PF04412.13 KXT06206.1 - 5.1e-127 423.9 0.0 6.5e-127 423.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF521) DUF126 PF01989.16 KXT06206.1 - 6.9e-31 105.9 0.1 1.8e-30 104.6 0.1 1.8 1 0 0 1 1 1 1 Aconitase X swivel domain MmgE_PrpD PF03972.14 KXT06207.1 - 4.5e-150 500.0 0.0 5.5e-150 499.7 0.0 1.1 1 0 0 1 1 1 1 MmgE/PrpD family Med16 PF11635.8 KXT06208.1 - 9.3e-88 295.0 0.0 1.3e-87 294.5 0.0 1.2 1 0 0 1 1 1 1 Mediator complex subunit 16 CsbD PF05532.12 KXT06210.1 - 6.1e-05 22.9 11.4 0.021 14.7 3.5 2.1 1 1 1 2 2 2 2 CsbD-like Cornichon PF03311.14 KXT06213.1 - 3.9e-50 169.3 10.8 4.5e-50 169.1 10.8 1.0 1 0 0 1 1 1 1 Cornichon protein Cornichon PF03311.14 KXT06214.1 - 3.1e-50 169.6 10.8 3.6e-50 169.4 10.8 1.0 1 0 0 1 1 1 1 Cornichon protein Cornichon PF03311.14 KXT06215.1 - 3.9e-50 169.3 10.8 4.5e-50 169.1 10.8 1.0 1 0 0 1 1 1 1 Cornichon protein DUF724 PF05266.14 KXT06216.1 - 0.0076 16.1 1.7 0.0076 16.1 1.7 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF724) DUF2894 PF11445.8 KXT06216.1 - 0.087 13.3 9.9 0.072 13.6 7.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2894) Fib_alpha PF08702.10 KXT06216.1 - 0.91 9.7 6.9 0.16 12.2 0.3 2.6 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF2151 PF10221.9 KXT06216.1 - 4.1 5.9 8.0 6.4 5.2 8.0 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator DUF16 PF01519.16 KXT06216.1 - 5.6 7.5 6.9 1.6 9.2 0.2 2.5 1 1 1 2 2 2 0 Protein of unknown function DUF16 DASH_Hsk3 PF08227.11 KXT06217.1 - 2.6e-19 69.3 2.4 4e-19 68.7 2.4 1.3 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like ADIP PF11559.8 KXT06217.1 - 0.077 13.1 0.8 0.092 12.8 0.8 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding CENP-F_N PF10481.9 KXT06217.1 - 0.12 12.0 0.7 0.14 11.7 0.7 1.0 1 0 0 1 1 1 0 Cenp-F N-terminal domain RNA12 PF10443.9 KXT06217.1 - 0.18 10.5 0.0 0.21 10.3 0.0 1.0 1 0 0 1 1 1 0 RNA12 protein DUF3453 PF11935.8 KXT06218.1 - 2.1e-67 227.1 0.4 2.1e-67 227.1 0.4 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) NAP PF00956.18 KXT06218.1 - 0.027 13.7 0.1 0.044 13.0 0.1 1.3 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) PALP PF00291.25 KXT06219.1 - 3.6e-75 253.1 0.7 5.4e-75 252.5 0.7 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 KXT06219.1 - 2.6e-44 148.9 0.0 1.7e-22 79.0 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase DUF4911 PF16256.5 KXT06219.1 - 0.058 13.4 0.0 0.51 10.3 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4911) p450 PF00067.22 KXT06234.1 - 2.5e-74 250.7 0.0 3.4e-74 250.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Toprim PF01751.22 KXT06235.1 - 0.13 12.5 0.8 11 6.3 0.8 2.8 1 1 0 1 1 1 0 Toprim domain DUF4807 PF16065.5 KXT06235.1 - 0.21 11.3 1.2 2 8.1 0.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4807) 120_Rick_ant PF12574.8 KXT06235.1 - 2.9 7.0 4.5 8.1 5.6 0.8 2.3 1 1 2 3 3 3 0 120 KDa Rickettsia surface antigen MFS_1 PF07690.16 KXT06236.1 - 1.7e-20 73.2 9.1 2.3e-20 72.8 9.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KXT06236.1 - 0.00048 19.5 3.5 0.00068 19.0 3.5 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB DUF4193 PF13834.6 KXT06238.1 - 0.039 14.5 0.3 0.081 13.4 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4193) DUF4193 PF13834.6 KXT06239.1 - 0.039 14.5 0.3 0.081 13.4 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4193) KH_8 PF17903.1 KXT06240.1 - 1.5e-06 28.2 0.0 3.3e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Krr1 KH1 domain DUF2786 PF10979.8 KXT06240.1 - 0.00013 21.8 0.5 0.00013 21.8 0.5 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF2786) KH_1 PF00013.29 KXT06240.1 - 0.049 13.5 3.6 0.054 13.3 0.6 2.5 3 0 0 3 3 3 0 KH domain Proteasome PF00227.26 KXT06241.1 - 2.4e-40 138.0 0.0 3e-40 137.8 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit tRNA-synt_1g PF09334.11 KXT06242.1 - 1.8e-90 303.5 0.0 3.5e-89 299.3 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (M) Ferric_reduct PF01794.19 KXT06242.1 - 2.4e-23 82.6 9.2 2.7e-23 82.4 7.2 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component tRNA-synt_1 PF00133.22 KXT06242.1 - 3.2e-22 78.5 0.3 5.6e-10 38.1 0.2 2.9 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) NAD_binding_6 PF08030.12 KXT06242.1 - 5.1e-09 36.4 0.0 1.2e-08 35.2 0.0 1.7 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KXT06242.1 - 1.7e-07 31.3 0.4 1.4e-06 28.4 0.4 2.4 1 1 0 1 1 1 1 FAD-binding domain tRNA-synt_1e PF01406.19 KXT06242.1 - 3.2e-05 23.4 0.0 0.025 13.9 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Ferric_reduct PF01794.19 KXT06243.1 - 8.2e-24 84.1 9.2 1.3e-23 83.4 7.2 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KXT06243.1 - 3.1e-09 37.1 0.0 5.8e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KXT06243.1 - 1.1e-07 31.9 0.7 8.5e-07 29.0 0.7 2.2 1 1 0 1 1 1 1 FAD-binding domain AlaDh_PNT_N PF05222.15 KXT06244.1 - 3.1e-29 102.0 0.0 4.9e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 KXT06244.1 - 0.00027 20.3 0.0 0.0025 17.2 0.0 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain tRNA-synt_1g PF09334.11 KXT06245.1 - 1.5e-91 307.1 0.0 5.8e-90 301.9 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KXT06245.1 - 1.7e-23 82.7 0.3 2e-10 39.6 0.3 3.0 2 2 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 KXT06245.1 - 3.8e-06 26.5 0.0 0.0072 15.7 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain UQ_con PF00179.26 KXT06246.1 - 2.6e-27 95.2 0.0 4.9e-27 94.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme VWA_2 PF13519.6 KXT06246.1 - 1.8e-14 54.3 0.3 2.2e-10 41.1 0.0 3.1 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA PF00092.28 KXT06246.1 - 1.8e-11 44.6 0.2 7.9e-10 39.3 0.0 3.0 2 0 0 2 2 2 1 von Willebrand factor type A domain U-box PF04564.15 KXT06246.1 - 3e-10 40.1 0.0 3.4e-09 36.8 0.0 2.7 3 0 0 3 3 3 1 U-box domain Par3_HAL_N_term PF12053.8 KXT06246.1 - 0.012 15.8 0.0 0.032 14.4 0.0 1.7 1 0 0 1 1 1 0 N-terminal of Par3 and HAL proteins VWA_3 PF13768.6 KXT06246.1 - 0.09 12.7 0.0 0.32 10.9 0.0 2.0 1 0 0 1 1 1 0 von Willebrand factor type A domain Glyco_hydro_7 PF00840.20 KXT06251.1 - 8.5e-198 657.4 16.4 9.8e-198 657.2 16.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 DUF3176 PF11374.8 KXT06252.1 - 1 9.6 4.9 5.8 7.2 0.1 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3176) DUF1211 PF06736.11 KXT06252.1 - 1.4 9.4 6.5 5.6 7.5 2.6 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1211) zf-met PF12874.7 KXT06255.1 - 4.4e-17 61.8 39.2 1.1e-05 25.6 0.5 6.8 7 0 0 7 7 7 5 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KXT06255.1 - 3.6e-12 46.0 34.7 0.018 15.9 0.6 8.0 6 1 1 7 7 7 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXT06255.1 - 5.4e-12 45.7 38.8 5e-05 23.5 0.4 7.0 7 0 0 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KXT06255.1 - 2.4e-10 40.6 35.2 0.012 15.9 1.0 7.0 1 1 5 6 6 6 5 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 KXT06255.1 - 9.8e-09 35.0 32.1 0.00015 21.7 1.9 6.7 6 1 0 6 6 6 3 C2H2-type zinc finger zf-C2H2 PF00096.26 KXT06255.1 - 1.9e-06 28.0 39.6 0.046 14.2 0.4 7.6 7 1 0 7 7 7 4 Zinc finger, C2H2 type Cadherin_C PF01049.17 KXT06255.1 - 0.0057 17.0 2.2 2.9 8.2 0.2 3.8 2 1 1 3 3 3 1 Cadherin cytoplasmic region HypA PF01155.19 KXT06255.1 - 0.052 13.6 17.8 0.84 9.7 1.4 4.3 2 2 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-Di19 PF05605.12 KXT06255.1 - 0.067 13.5 0.4 0.067 13.5 0.4 4.3 3 1 2 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 KXT06255.1 - 0.13 12.7 29.2 4.6 7.8 0.9 7.4 7 0 0 7 7 7 0 Zinc-finger double domain zf-C2H2_11 PF16622.5 KXT06255.1 - 0.33 10.8 14.3 0.2 11.5 0.3 4.8 5 0 0 5 5 5 0 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 KXT06255.1 - 0.66 10.1 28.5 2.9 8.1 0.2 6.2 5 1 1 6 6 6 0 Zinc ribbon domain ABM PF03992.16 KXT06255.1 - 8.7 6.5 8.4 27 5.0 0.0 3.8 4 1 1 5 5 5 0 Antibiotic biosynthesis monooxygenase ATP-grasp_3 PF02655.14 KXT06256.1 - 0.016 15.3 0.0 0.059 13.4 0.0 1.9 2 1 0 2 2 2 0 ATP-grasp domain DUF3416 PF11896.8 KXT06256.1 - 0.099 12.9 0.1 0.23 11.7 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3416) Pex14_N PF04695.13 KXT06258.1 - 4.1e-12 47.0 27.2 2e-10 41.5 24.6 3.1 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Lin-8 PF03353.15 KXT06258.1 - 6.3 6.3 11.7 6.4 6.2 10.7 1.6 1 1 0 1 1 1 0 Ras-mediated vulval-induction antagonist Trm112p PF03966.16 KXT06259.1 - 3.4e-13 50.0 0.1 5e-13 49.4 0.1 1.3 1 0 0 1 1 1 1 Trm112p-like protein Methyltransf_11 PF08241.12 KXT06260.1 - 2.5e-16 60.1 0.1 5.6e-16 59.0 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXT06260.1 - 1.8e-13 51.0 0.1 3.5e-13 50.1 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXT06260.1 - 1.9e-09 37.6 0.0 2.9e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXT06260.1 - 1.3e-08 34.5 0.0 1.8e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KXT06260.1 - 2.5e-08 33.9 0.0 3.7e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXT06260.1 - 3.7e-08 34.0 0.0 6.8e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 KXT06260.1 - 3e-05 23.2 0.0 4e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase MTS PF05175.14 KXT06260.1 - 6.1e-05 22.6 0.0 0.00012 21.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 KXT06260.1 - 0.00055 19.6 0.1 0.00087 18.9 0.1 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW FtsJ PF01728.19 KXT06260.1 - 0.0026 17.9 0.0 0.0038 17.4 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 KXT06260.1 - 0.0091 16.0 0.1 0.016 15.2 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KXT06260.1 - 0.068 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Glyco_hydro_3_C PF01915.22 KXT06261.1 - 3.7e-43 147.9 0.0 6.3e-43 147.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXT06261.1 - 8.2e-36 124.0 0.0 2.3e-35 122.5 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXT06261.1 - 6e-17 61.5 0.1 1e-16 60.8 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain NatB_MDM20 PF09797.9 KXT06262.1 - 6.1e-37 127.5 0.1 6.1e-37 127.5 0.1 1.6 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit DUF1993 PF09351.10 KXT06262.1 - 0.031 14.4 1.4 0.22 11.6 1.4 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF1993) Acetyltransf_3 PF13302.7 KXT06263.1 - 5.7e-23 82.1 0.0 9.1e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyco_hydro_4C PF11975.8 KXT06263.1 - 0.039 14.0 0.0 1.9 8.5 0.0 2.1 2 0 0 2 2 2 0 Family 4 glycosyl hydrolase C-terminal domain Acetyltransf_8 PF13523.6 KXT06263.1 - 0.088 12.5 0.9 2.1 8.1 0.5 2.5 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain Proteasome PF00227.26 KXT06265.1 - 1.9e-29 102.5 0.2 4.5e-29 101.3 0.2 1.8 1 1 0 1 1 1 1 Proteasome subunit HSP70 PF00012.20 KXT06267.1 - 5.9e-09 34.7 0.0 4.1e-07 28.6 0.0 2.2 2 0 0 2 2 2 2 Hsp70 protein Pkinase PF00069.25 KXT06268.1 - 9.3e-68 228.4 0.0 1.4e-67 227.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT06268.1 - 2.5e-48 164.6 0.0 4.8e-48 163.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXT06268.1 - 0.0014 17.5 0.3 0.0026 16.6 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KXT06268.1 - 0.0046 16.3 0.0 0.044 13.1 0.0 2.2 2 0 0 2 2 2 1 Kinase-like IDO PF01231.18 KXT06269.1 - 1.7e-33 116.1 0.0 2.3e-33 115.7 0.0 1.3 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Nod_GRP PF07806.11 KXT06270.1 - 0.0025 17.6 0.7 0.0046 16.8 0.7 1.4 1 0 0 1 1 1 1 Nodule-specific GRP repeat Nod_GRP PF07806.11 KXT06271.1 - 0.0025 17.6 0.7 0.0046 16.8 0.7 1.4 1 0 0 1 1 1 1 Nodule-specific GRP repeat ADH_zinc_N PF00107.26 KXT06273.1 - 9.3e-27 93.6 0.5 1.4e-26 93.0 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXT06273.1 - 5e-18 66.4 0.1 1e-17 65.4 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXT06273.1 - 9.4e-07 28.7 0.0 4.1e-06 26.6 0.0 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.21 KXT06273.1 - 0.027 14.2 0.2 0.041 13.6 0.2 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Evr1_Alr PF04777.13 KXT06275.1 - 8.1e-27 93.6 1.0 1.4e-26 92.9 0.3 1.8 1 1 1 2 2 2 1 Erv1 / Alr family TarH PF02203.15 KXT06275.1 - 0.045 13.7 0.0 0.062 13.2 0.0 1.3 1 0 0 1 1 1 0 Tar ligand binding domain homologue APOBEC1 PF18769.1 KXT06275.1 - 0.098 12.9 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 APOBEC1 Aminotran_4 PF01063.19 KXT06276.1 - 2.4e-24 86.4 0.0 3.2e-24 86.1 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV DAO PF01266.24 KXT06277.1 - 1.2e-38 133.6 2.8 1.5e-38 133.3 2.8 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXT06277.1 - 0.00023 21.3 0.5 0.00059 20.0 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KXT06277.1 - 0.00056 19.1 0.7 0.00089 18.4 0.7 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KXT06277.1 - 0.0011 18.3 0.0 0.0031 16.8 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXT06277.1 - 0.0027 17.0 0.1 0.0049 16.1 0.1 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 KXT06277.1 - 0.004 17.2 0.6 0.021 14.8 0.3 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KXT06277.1 - 0.0068 15.7 0.0 0.098 11.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXT06277.1 - 0.15 11.1 3.7 0.2 10.7 3.7 1.4 1 1 0 1 1 1 0 FAD binding domain zf-C3HC4_4 PF15227.6 KXT06278.1 - 1.7e-09 37.7 8.6 1.7e-09 37.7 8.6 2.5 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KXT06278.1 - 1.6e-08 34.3 8.7 1.6e-08 34.3 8.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXT06278.1 - 2.2e-08 34.0 5.3 4.7e-08 32.9 5.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KXT06278.1 - 1.3e-07 31.4 8.9 1.3e-07 31.4 8.9 2.9 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXT06278.1 - 1.5e-07 31.6 7.0 1.5e-07 31.6 7.0 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 KXT06278.1 - 2.4e-06 27.3 6.6 2.4e-06 27.3 6.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXT06278.1 - 5.5e-06 26.2 8.3 5.5e-06 26.2 8.3 1.9 2 0 0 2 2 1 1 zinc-RING finger domain MqsA_antitoxin PF15731.5 KXT06278.1 - 0.012 15.7 0.4 0.035 14.2 0.0 1.9 2 0 0 2 2 2 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA zf-ANAPC11 PF12861.7 KXT06278.1 - 0.013 15.5 1.4 0.013 15.5 1.4 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger RecR PF02132.15 KXT06278.1 - 0.12 11.9 5.7 3 7.5 0.2 3.4 3 0 0 3 3 3 0 RecR protein zf-RING_10 PF16685.5 KXT06278.1 - 0.22 11.7 4.8 0.46 10.7 4.8 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 KXT06278.1 - 0.5 10.3 11.2 0.04 13.8 4.5 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 KXT06278.1 - 0.81 9.6 7.2 0.083 12.8 2.0 2.0 2 1 0 2 2 2 0 zf-RING of BARD1-type protein zinc_ribbon_9 PF14369.6 KXT06278.1 - 0.81 10.0 10.1 0.41 10.9 2.6 3.4 3 0 0 3 3 3 0 zinc-ribbon zf-LITAF-like PF10601.9 KXT06278.1 - 1.8 8.9 10.6 4.4 7.6 4.8 2.6 2 1 0 2 2 2 0 LITAF-like zinc ribbon domain FYVE PF01363.21 KXT06278.1 - 2 8.6 9.2 8.8 6.5 6.5 2.6 2 1 0 2 2 2 0 FYVE zinc finger zf-RING_4 PF14570.6 KXT06278.1 - 2.2 8.1 10.4 1.6 8.6 4.4 2.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DZR PF12773.7 KXT06278.1 - 3.4 7.8 12.4 3e+02 1.5 12.6 3.0 1 1 0 1 1 1 0 Double zinc ribbon UvrD_C_2 PF13538.6 KXT06281.1 - 0.00014 21.6 0.0 0.00026 20.8 0.0 1.4 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 KXT06281.1 - 0.00034 20.4 0.0 0.00045 20.0 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Herpes_Helicase PF02689.14 KXT06281.1 - 0.004 15.2 0.0 0.005 14.8 0.0 1.0 1 0 0 1 1 1 1 Helicase NmrA PF05368.13 KXT06282.1 - 4e-05 23.3 0.1 4.7e-05 23.0 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family FapA PF03961.13 KXT06283.1 - 5.7 5.4 12.0 10 4.6 0.3 2.1 2 0 0 2 2 2 0 Flagellar Assembly Protein A Cytochrom_C1 PF02167.15 KXT06284.1 - 3.8e-92 308.0 0.0 4.8e-92 307.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 KXT06284.1 - 0.0081 16.5 0.0 0.017 15.4 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III FAD_binding_3 PF01494.19 KXT06285.1 - 2.5e-22 79.6 0.0 1.1e-14 54.4 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KXT06285.1 - 1.6e-07 31.4 0.4 4e-07 30.2 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXT06285.1 - 3.9e-06 26.7 0.6 0.00029 20.5 0.7 2.3 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXT06285.1 - 0.00015 21.2 0.2 0.004 16.4 0.4 2.3 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXT06285.1 - 0.0037 16.4 2.0 0.0078 15.3 1.9 1.7 1 1 1 2 2 2 1 FAD binding domain Thi4 PF01946.17 KXT06285.1 - 0.047 12.9 0.1 0.077 12.2 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 KXT06285.1 - 0.08 12.2 0.3 0.15 11.3 0.3 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXT06285.1 - 0.1 11.4 0.2 0.16 10.8 0.2 1.3 1 0 0 1 1 1 0 Tryptophan halogenase UDPG_MGDP_dh_N PF03721.14 KXT06285.1 - 0.11 12.1 0.5 0.28 10.7 0.1 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.27 KXT06285.1 - 0.12 13.0 0.1 0.35 11.5 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 KXT06285.1 - 0.14 11.4 0.3 0.23 10.8 0.3 1.2 1 0 0 1 1 1 0 ThiF family GIDA PF01134.22 KXT06285.1 - 0.17 10.9 1.1 0.3 10.1 1.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A AAA_16 PF13191.6 KXT06287.1 - 3.5e-12 47.0 0.3 5.4e-10 39.9 0.3 2.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXT06287.1 - 7.5e-10 39.2 0.1 5.1e-09 36.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KXT06287.1 - 2.2e-09 37.8 0.0 6.7e-09 36.3 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KXT06287.1 - 5e-06 26.9 0.2 6.2e-05 23.4 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_lid_10 PF17872.1 KXT06287.1 - 5.4e-06 26.5 0.3 1.8e-05 24.8 0.3 1.9 1 0 0 1 1 1 1 AAA lid domain ATPase_2 PF01637.18 KXT06287.1 - 8.7e-06 25.8 0.4 0.00029 20.8 0.1 2.8 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea Cdc6_C PF09079.11 KXT06287.1 - 4.1e-05 23.5 0.1 0.00052 19.9 0.1 2.4 1 1 0 1 1 1 1 CDC6, C terminal winged helix domain AAA_30 PF13604.6 KXT06287.1 - 0.00031 20.5 0.0 0.00073 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KXT06287.1 - 0.00042 20.4 0.0 0.0008 19.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 KXT06287.1 - 0.0017 17.9 0.1 0.0068 16.0 0.1 1.9 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain T2SSE PF00437.20 KXT06287.1 - 0.004 16.2 0.0 0.0077 15.3 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_7 PF12775.7 KXT06287.1 - 0.0053 16.3 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region NTPase_1 PF03266.15 KXT06287.1 - 0.0058 16.5 0.0 0.1 12.5 0.0 2.5 2 0 0 2 2 2 1 NTPase NB-ARC PF00931.22 KXT06287.1 - 0.0085 15.3 0.0 0.016 14.4 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain DUF2075 PF09848.9 KXT06287.1 - 0.015 14.6 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 KXT06287.1 - 0.019 14.9 0.3 0.086 12.8 0.0 2.2 2 1 0 2 2 2 0 NACHT domain DAP3 PF10236.9 KXT06287.1 - 0.021 14.0 0.2 0.21 10.7 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Rad17 PF03215.15 KXT06287.1 - 0.029 14.3 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain PIF1 PF05970.14 KXT06287.1 - 0.03 13.5 0.0 0.054 12.7 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase RNA12 PF10443.9 KXT06287.1 - 0.051 12.3 0.0 0.1 11.3 0.0 1.4 1 0 0 1 1 1 0 RNA12 protein RNA_helicase PF00910.22 KXT06287.1 - 0.13 12.6 0.0 0.33 11.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Methyltransf_11 PF08241.12 KXT06289.1 - 3.8e-23 81.9 0.0 6.4e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXT06289.1 - 6.6e-22 77.9 0.0 8.9e-22 77.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXT06289.1 - 3e-21 75.9 0.0 5.5e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXT06289.1 - 2.4e-14 53.9 0.0 3.8e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXT06289.1 - 1.4e-13 50.7 0.0 2.3e-13 50.0 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KXT06289.1 - 3.1e-12 46.6 0.0 4e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXT06289.1 - 6.3e-07 29.1 0.0 9.6e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_PK PF05891.12 KXT06289.1 - 8.5e-06 25.4 0.0 1.3e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_2 PF00891.18 KXT06289.1 - 4.2e-05 22.9 0.0 5.4e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain DREV PF05219.12 KXT06289.1 - 0.00013 21.2 0.0 0.00019 20.6 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_29 PF03141.16 KXT06289.1 - 0.0013 17.3 0.1 0.0027 16.3 0.0 1.5 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MetW PF07021.12 KXT06289.1 - 0.0018 17.9 0.0 0.0027 17.3 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW CheR PF01739.18 KXT06289.1 - 0.0056 16.2 0.1 3.2 7.2 0.0 2.7 2 1 1 3 3 3 1 CheR methyltransferase, SAM binding domain Methyltransf_16 PF10294.9 KXT06289.1 - 0.012 15.4 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_32 PF13679.6 KXT06289.1 - 0.012 15.6 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 KXT06289.1 - 0.022 13.8 0.0 0.032 13.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_4 PF02390.17 KXT06289.1 - 0.023 14.2 0.0 0.048 13.1 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase PCMT PF01135.19 KXT06289.1 - 0.048 13.4 0.0 0.07 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 KXT06289.1 - 0.056 13.1 0.0 0.097 12.3 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltransf_18 PF12847.7 KXT06289.1 - 0.087 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ecm29 PF13001.7 KXT06290.1 - 5.9e-159 529.9 0.1 1.3e-155 518.9 0.0 3.6 3 0 0 3 3 3 2 Proteasome stabiliser Vac14_Fab1_bd PF12755.7 KXT06290.1 - 1.1e-09 38.7 0.9 0.0046 17.5 0.0 6.1 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 KXT06290.1 - 4.3e-08 32.7 6.2 0.22 11.9 0.2 8.7 9 0 0 9 9 9 1 HEAT repeat HEAT_EZ PF13513.6 KXT06290.1 - 3e-06 27.6 8.3 6.6 7.4 0.4 8.1 8 1 0 8 8 8 2 HEAT-like repeat IFRD PF05004.13 KXT06290.1 - 0.06 12.4 6.0 0.48 9.5 0.0 4.1 4 1 0 4 4 4 0 Interferon-related developmental regulator (IFRD) Adaptin_N PF01602.20 KXT06290.1 - 0.13 10.8 6.2 1.1 7.7 0.1 3.2 3 1 0 3 3 3 0 Adaptin N terminal region Ecm29 PF13001.7 KXT06292.1 - 8.1e-151 503.1 0.1 1.5e-147 492.2 0.0 3.6 3 0 0 3 3 3 2 Proteasome stabiliser Vac14_Fab1_bd PF12755.7 KXT06292.1 - 1.9e-09 38.0 0.4 0.0051 17.4 0.0 5.8 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 KXT06292.1 - 1.1e-07 31.4 6.2 0.25 11.7 0.2 8.4 9 0 0 9 9 9 1 HEAT repeat HEAT_EZ PF13513.6 KXT06292.1 - 5.3e-06 26.8 8.0 7.3 7.2 0.4 7.9 8 1 0 8 8 8 2 HEAT-like repeat IFRD PF05004.13 KXT06292.1 - 0.079 12.1 5.8 0.53 9.3 0.0 4.0 4 1 0 4 4 4 0 Interferon-related developmental regulator (IFRD) Adaptin_N PF01602.20 KXT06292.1 - 0.27 9.8 6.8 1.3 7.5 0.1 3.1 3 1 0 3 3 3 0 Adaptin N terminal region M20_dimer PF07687.14 KXT06296.1 - 4.1e-21 75.0 0.1 6.8e-21 74.2 0.1 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KXT06296.1 - 2.3e-18 66.7 0.6 2.4e-16 60.1 0.6 2.1 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 KXT06296.1 - 6.4e-05 22.7 0.3 0.0002 21.1 0.0 2.0 3 0 0 3 3 3 1 Peptidase family M28 FlxA PF14282.6 KXT06297.1 - 0.12 12.3 0.1 0.12 12.3 0.1 9.0 3 1 5 8 8 8 0 FlxA-like protein DMRL_synthase PF00885.19 KXT06298.1 - 2.9e-20 72.5 0.0 3.3e-20 72.3 0.0 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase DUF3431 PF11913.8 KXT06299.1 - 1.3e-70 237.5 0.3 1.7e-70 237.1 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) DUF3431 PF11913.8 KXT06300.1 - 1.3e-70 237.5 0.3 1.7e-70 237.1 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Dehydratase_MU PF02288.15 KXT06301.1 - 0.11 12.4 0.1 0.28 11.1 0.1 1.7 1 0 0 1 1 1 0 Dehydratase medium subunit DUF4482 PF14818.6 KXT06302.1 - 0.057 14.3 2.4 0.071 14.0 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4482) eIF2_C PF09173.11 KXT06304.1 - 1.9e-34 117.8 0.9 4.4e-34 116.6 0.9 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 KXT06304.1 - 9.8e-24 84.0 1.0 6.1e-23 81.4 1.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KXT06304.1 - 8e-12 45.4 0.3 1.7e-11 44.3 0.3 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 KXT06304.1 - 0.0039 17.1 0.1 0.045 13.7 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 KXT06304.1 - 0.0047 17.0 0.0 0.0095 16.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 KXT06304.1 - 0.039 14.0 0.1 0.086 12.9 0.1 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain B_lectin PF01453.24 KXT06307.1 - 2.5e-05 24.8 0.0 0.015 15.8 0.0 2.5 1 1 2 3 3 3 3 D-mannose binding lectin AbrB-like PF14250.6 KXT06307.1 - 0.066 13.3 0.1 0.8 9.8 0.0 2.6 1 1 2 3 3 3 0 AbrB-like transcriptional regulator SIS PF01380.22 KXT06308.1 - 9.1e-58 193.8 0.1 1.9e-31 108.6 0.0 2.4 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 KXT06308.1 - 9.9e-17 61.4 0.0 1.9e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KXT06308.1 - 4.2e-11 42.8 0.0 9.8e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KXT06308.1 - 0.0012 17.8 0.0 0.0022 17.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 KXT06308.1 - 0.16 12.0 0.0 1.7 8.7 0.0 2.6 2 1 0 2 2 2 0 SIS domain CHORD PF04968.12 KXT06309.1 - 0.066 13.9 3.0 1.1 10.0 0.4 2.4 2 0 0 2 2 2 0 CHORD DUF3328 PF11807.8 KXT06310.1 - 7.2e-34 117.5 2.9 9.9e-34 117.0 2.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF5345 PF17280.2 KXT06310.1 - 0.11 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5345) Transp_cyt_pur PF02133.15 KXT06310.1 - 0.22 10.3 0.9 0.3 9.8 0.9 1.1 1 0 0 1 1 1 0 Permease for cytosine/purines, uracil, thiamine, allantoin C2 PF00168.30 KXT06313.1 - 5.7e-24 84.4 0.0 4.7e-12 46.1 0.0 2.7 2 0 0 2 2 2 2 C2 domain C2 PF00168.30 KXT06314.1 - 5.7e-24 84.4 0.0 4.7e-12 46.1 0.0 2.7 2 0 0 2 2 2 2 C2 domain C2 PF00168.30 KXT06315.1 - 5.7e-24 84.4 0.0 4.7e-12 46.1 0.0 2.7 2 0 0 2 2 2 2 C2 domain AA_permease PF00324.21 KXT06316.1 - 2e-147 491.6 32.9 2.3e-147 491.4 32.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXT06316.1 - 1.1e-38 133.2 34.7 1.4e-38 132.9 34.7 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4781 PF16013.5 KXT06316.1 - 0.08 11.7 0.3 0.15 10.9 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) R3H PF01424.22 KXT06317.1 - 1.5e-15 56.9 0.4 5.8e-15 55.0 0.1 2.1 2 0 0 2 2 2 1 R3H domain zf-NF-X1 PF01422.17 KXT06317.1 - 7.2e-07 29.2 39.5 4.1e-05 23.5 14.0 13.5 16 1 0 16 16 16 7 NF-X1 type zinc finger FoP_duplication PF13865.6 KXT06317.1 - 9.7 6.8 19.1 20 5.8 8.8 2.8 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 F-box-like_2 PF13013.6 KXT06320.1 - 0.046 13.7 0.0 0.075 13.0 0.0 1.5 1 0 0 1 1 1 0 F-box-like domain PCI PF01399.27 KXT06321.1 - 2.7e-11 43.9 0.3 9.3e-11 42.2 0.1 2.1 2 0 0 2 2 2 1 PCI domain eIF3m_C_helix PF18005.1 KXT06321.1 - 6.3e-11 41.8 1.0 6.3e-11 41.8 1.0 1.8 2 0 0 2 2 2 1 eIF3 subunit M, C-terminal helix DUF2937 PF11157.8 KXT06321.1 - 0.091 12.5 1.4 2.9 7.6 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2937) MFS_1 PF07690.16 KXT06322.1 - 6.2e-46 156.9 37.1 8.1e-46 156.6 37.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXT06322.1 - 6.8e-09 35.1 13.0 6.8e-09 35.1 13.0 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KXT06322.1 - 0.00027 19.5 2.8 0.00027 19.5 2.8 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) CAP_N PF01213.19 KXT06322.1 - 0.2 11.1 5.2 0.29 10.6 5.2 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal G-patch PF01585.23 KXT06323.1 - 0.00057 19.7 0.0 0.005 16.7 0.0 2.5 1 1 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KXT06323.1 - 0.036 14.2 0.1 0.036 14.2 0.1 3.1 2 1 0 2 2 2 0 G-patch domain CDC45 PF02724.14 KXT06323.1 - 0.34 9.2 21.4 0.43 8.8 21.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DDHD PF02862.17 KXT06323.1 - 2.2 8.4 10.0 4.1 7.5 10.0 1.4 1 0 0 1 1 1 0 DDHD domain DUF4551 PF15087.6 KXT06323.1 - 2.6 6.8 13.9 3.5 6.3 13.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) eIF3_subunit PF08597.10 KXT06323.1 - 2.6 7.9 32.8 4.2 7.2 32.8 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF4407 PF14362.6 KXT06323.1 - 4.5 6.5 7.1 6.1 6.1 7.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SLC12 PF03522.15 KXT06323.1 - 6 5.8 12.1 8.8 5.2 12.1 1.2 1 0 0 1 1 1 0 Solute carrier family 12 AAA_11 PF13086.6 KXT06323.1 - 9.6 5.9 14.4 15 5.3 14.4 1.2 1 0 0 1 1 1 0 AAA domain AKAP7_RIRII_bdg PF10470.9 KXT06324.1 - 0.00014 21.9 2.3 1.5e+02 2.5 0.0 7.0 2 2 6 8 8 8 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein ANAPC15 PF15243.6 KXT06324.1 - 0.0036 17.7 8.6 44 4.6 8.2 4.1 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 15 TGase_elicitor PF16683.5 KXT06324.1 - 0.011 14.5 3.1 11 4.7 0.1 3.4 1 1 2 4 4 4 0 Transglutaminase elicitor Usp PF00582.26 KXT06324.1 - 0.045 14.3 3.4 12 6.4 1.3 3.7 1 1 1 2 2 2 0 Universal stress protein family AMP_N PF05195.16 KXT06324.1 - 0.44 10.3 6.8 18 5.1 1.1 3.6 1 1 1 2 2 2 0 Aminopeptidase P, N-terminal domain UL41A PF17591.2 KXT06324.1 - 2.3 8.4 20.4 9.1 6.5 0.8 4.7 1 1 5 6 6 6 0 Herpesvirus UL41A Menin PF05053.13 KXT06324.1 - 6 5.1 11.4 9 4.5 0.8 3.1 1 1 3 5 5 5 0 Menin AKAP7_RIRII_bdg PF10470.9 KXT06325.1 - 0.00014 21.9 2.3 1.5e+02 2.5 0.0 7.0 2 2 6 8 8 8 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein ANAPC15 PF15243.6 KXT06325.1 - 0.0036 17.7 8.6 44 4.6 8.2 4.1 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 15 TGase_elicitor PF16683.5 KXT06325.1 - 0.011 14.5 3.1 11 4.7 0.1 3.4 1 1 2 4 4 4 0 Transglutaminase elicitor Usp PF00582.26 KXT06325.1 - 0.045 14.3 3.4 12 6.4 1.3 3.7 1 1 1 2 2 2 0 Universal stress protein family AMP_N PF05195.16 KXT06325.1 - 0.44 10.3 6.8 18 5.1 1.1 3.6 1 1 1 2 2 2 0 Aminopeptidase P, N-terminal domain UL41A PF17591.2 KXT06325.1 - 2.3 8.4 20.4 9.1 6.5 0.8 4.7 1 1 5 6 6 6 0 Herpesvirus UL41A Menin PF05053.13 KXT06325.1 - 6 5.1 11.4 9 4.5 0.8 3.1 1 1 3 5 5 5 0 Menin WD40 PF00400.32 KXT06326.1 - 2.1e-54 180.2 34.6 1.2e-08 35.4 0.6 9.1 8 1 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXT06326.1 - 1.7e-20 73.1 2.1 0.0078 16.5 0.0 6.5 2 2 5 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KXT06326.1 - 0.0003 19.9 1.2 0.054 12.5 0.1 3.8 2 2 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein NLE PF08154.12 KXT06326.1 - 0.00058 20.3 0.0 0.0012 19.4 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain eIF2A PF08662.11 KXT06326.1 - 0.0013 18.7 0.3 1.1 9.1 0.0 3.6 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KXT06326.1 - 0.0052 15.5 1.3 2.3 6.7 0.0 3.7 4 1 0 4 4 4 1 Nucleoporin Nup120/160 DUF1652 PF07865.11 KXT06326.1 - 0.0068 16.2 0.0 0.053 13.3 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1652) Nucleoporin_N PF08801.11 KXT06326.1 - 0.044 12.5 0.8 15 4.2 0.0 3.3 2 2 2 4 4 4 0 Nup133 N terminal like TFIIIC_delta PF12657.7 KXT06326.1 - 0.17 11.8 2.7 14 5.6 0.1 4.1 3 2 1 4 4 4 0 Transcription factor IIIC subunit delta N-term PD40 PF07676.12 KXT06326.1 - 0.97 9.5 2.8 91 3.2 0.0 4.2 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Sugarporin_N PF11471.8 KXT06327.1 - 1.3 9.1 2.8 1.5 8.8 0.5 2.3 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension SWIRM-assoc_2 PF16496.5 KXT06328.1 - 0.024 13.5 1.6 0.028 13.3 1.6 1.0 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Metallophos PF00149.28 KXT06329.1 - 2.7e-13 50.9 0.3 4.9e-13 50.0 0.3 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Pyr_redox_2 PF07992.14 KXT06330.1 - 1.9e-42 145.5 0.0 2.3e-42 145.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXT06330.1 - 7.9e-09 36.0 0.0 1.6e-06 28.6 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXT06330.1 - 1.6e-05 24.2 0.0 0.0043 16.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Methyltransf_16 PF10294.9 KXT06330.1 - 0.0074 16.0 0.0 0.027 14.2 0.0 1.8 2 0 0 2 2 2 1 Lysine methyltransferase DUF4147 PF13660.6 KXT06330.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4147) DnaJ PF00226.31 KXT06331.1 - 3.2e-11 43.2 0.8 1.4e-09 38.0 0.1 2.4 2 0 0 2 2 2 2 DnaJ domain Glyco_hydro_18 PF00704.28 KXT06333.1 - 2.7e-14 53.6 1.7 3.2e-14 53.4 1.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 zf-MYND PF01753.18 KXT06334.1 - 2.4e-06 27.5 20.8 2.4e-06 27.5 20.8 4.0 3 1 0 3 3 3 1 MYND finger CHORD PF04968.12 KXT06335.1 - 0.022 15.5 0.1 0.037 14.8 0.1 1.3 1 0 0 1 1 1 0 CHORD Ets PF00178.22 KXT06335.1 - 0.6 10.6 2.7 2.9 8.4 0.0 2.4 1 1 2 3 3 3 0 Ets-domain Zn_clus PF00172.18 KXT06336.1 - 0.051 13.7 6.2 0.12 12.6 6.2 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Hydantoinase_B PF02538.14 KXT06337.1 - 2e-187 623.7 0.2 2.7e-187 623.3 0.2 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KXT06337.1 - 3.7e-89 298.8 0.1 2.8e-88 295.9 0.0 2.2 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KXT06337.1 - 3.5e-52 176.7 0.1 1.1e-49 168.6 0.0 2.6 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Epimerase PF01370.21 KXT06337.1 - 3.8e-05 23.3 0.0 0.072 12.5 0.0 2.5 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KXT06337.1 - 0.0028 18.1 0.0 0.0068 16.8 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 KXT06337.1 - 0.0038 17.2 0.0 0.009 15.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H-binding PepSY_2 PF13670.6 KXT06338.1 - 0.1 12.6 0.2 0.2 11.7 0.0 1.6 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain CMD PF02627.20 KXT06340.1 - 1.9e-08 34.2 0.3 7e-08 32.4 0.2 1.9 2 1 0 2 2 2 1 Carboxymuconolactone decarboxylase family DUF507 PF04368.13 KXT06340.1 - 0.015 15.2 1.2 0.024 14.6 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF507) Pox_VLTF3 PF04947.14 KXT06340.1 - 0.078 12.7 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Poxvirus Late Transcription Factor VLTF3 like AIM5 PF17050.5 KXT06340.1 - 0.09 13.6 0.2 0.09 13.6 0.2 2.1 2 0 0 2 2 2 0 Altered inheritance of mitochondria 5 SSF PF00474.17 KXT06341.1 - 2.6e-18 66.1 33.8 4.4e-18 65.3 33.8 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family Pex2_Pex12 PF04757.14 KXT06342.1 - 3.6e-44 151.0 5.6 4.8e-44 150.6 5.6 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.6 KXT06342.1 - 5.3e-11 42.7 10.1 1.1e-10 41.7 10.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXT06342.1 - 1.6e-09 37.5 11.2 3.4e-09 36.4 11.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXT06342.1 - 1.9e-09 37.3 6.9 3.1e-09 36.5 6.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXT06342.1 - 3.7e-09 36.3 8.2 3.7e-09 36.3 8.2 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXT06342.1 - 2.2e-07 30.8 8.9 5.1e-07 29.6 8.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KXT06342.1 - 4.4e-07 29.7 6.5 8.2e-07 28.9 6.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KXT06342.1 - 6e-07 29.6 7.5 1.4e-06 28.5 7.5 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KXT06342.1 - 9.6e-06 25.4 7.7 1.7e-05 24.6 7.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KXT06342.1 - 4.3e-05 23.6 9.1 7.6e-05 22.8 9.1 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 KXT06342.1 - 0.0015 18.4 2.6 0.0028 17.5 2.6 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Nse PF11789.8 KXT06342.1 - 0.0069 16.2 2.4 0.016 15.0 2.4 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 KXT06342.1 - 0.019 14.7 6.2 0.042 13.6 6.2 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 KXT06342.1 - 0.021 15.0 6.7 0.046 13.9 6.7 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 KXT06342.1 - 0.052 13.6 7.3 0.21 11.7 7.3 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger SBP56 PF05694.11 KXT06342.1 - 0.19 10.5 0.0 0.27 10.0 0.0 1.1 1 0 0 1 1 1 0 56kDa selenium binding protein (SBP56) zf-RING_11 PF17123.5 KXT06342.1 - 0.47 10.2 2.7 1.3 8.9 2.7 1.8 1 0 0 1 1 1 0 RING-like zinc finger IBR PF01485.21 KXT06342.1 - 0.49 10.6 5.1 1.5 9.1 5.1 1.9 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain DZR PF12773.7 KXT06342.1 - 0.88 9.7 5.1 2 8.5 5.1 1.6 1 0 0 1 1 1 0 Double zinc ribbon PAC4 PF16093.5 KXT06343.1 - 0.053 13.7 0.0 0.4 10.9 0.0 2.0 2 0 0 2 2 2 0 Proteasome assembly chaperone 4 Enolase_C PF00113.22 KXT06344.1 - 5.3e-153 508.5 0.4 7.2e-153 508.0 0.4 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KXT06344.1 - 2.6e-56 189.4 0.2 5e-56 188.5 0.2 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 KXT06344.1 - 1e-07 31.8 0.0 1.6e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like DNA_ligase_aden PF01653.18 KXT06344.1 - 0.024 13.7 0.1 0.041 13.0 0.1 1.2 1 0 0 1 1 1 0 NAD-dependent DNA ligase adenylation domain MAAL_C PF07476.11 KXT06344.1 - 0.038 13.1 2.6 0.06 12.5 0.7 2.1 2 1 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus PIR PF00399.19 KXT06345.1 - 5.7e-07 28.9 12.8 0.12 11.9 0.3 3.8 3 0 0 3 3 3 3 Yeast PIR protein repeat zf-TFIIB PF13453.6 KXT06345.1 - 0.02 14.2 2.8 0.41 10.0 0.3 2.6 2 0 0 2 2 2 0 Transcription factor zinc-finger IBR PF01485.21 KXT06345.1 - 0.94 9.8 6.8 4.3 7.6 0.3 2.8 2 1 1 3 3 3 0 IBR domain, a half RING-finger domain Cys_knot PF00007.22 KXT06345.1 - 3.2 8.1 13.6 12 6.3 6.6 2.7 2 1 0 2 2 2 0 Cystine-knot domain ArfGap PF01412.18 KXT06346.1 - 3.9e-35 120.5 0.0 3.9e-35 120.5 0.0 2.4 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 KXT06346.1 - 1.4e-18 67.5 17.0 2.7e-18 66.6 17.0 1.3 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 KXT06346.1 - 2.9e-13 50.2 1.4 7.1e-13 49.0 0.0 2.4 3 0 0 3 3 3 1 PH domain GFA PF04828.14 KXT06348.1 - 1.9e-21 76.2 0.5 3e-21 75.6 0.5 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Zn_ribbon_recom PF13408.6 KXT06348.1 - 0.011 16.2 0.8 0.07 13.6 0.0 2.2 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain HECA PF15353.6 KXT06348.1 - 0.11 12.7 3.0 0.28 11.5 3.0 1.7 1 1 0 1 1 1 0 Headcase protein family homologue GFA PF04828.14 KXT06349.1 - 1.9e-21 76.2 0.5 3e-21 75.6 0.5 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Zn_ribbon_recom PF13408.6 KXT06349.1 - 0.011 16.2 0.8 0.07 13.6 0.0 2.2 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain HECA PF15353.6 KXT06349.1 - 0.11 12.7 3.0 0.28 11.5 3.0 1.7 1 1 0 1 1 1 0 Headcase protein family homologue AAA PF00004.29 KXT06350.1 - 8.5e-43 146.0 0.0 1.5e-42 145.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KXT06350.1 - 6.9e-11 41.9 0.2 3.2e-10 39.8 0.1 2.1 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KXT06350.1 - 3.4e-10 39.6 0.0 7.5e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KXT06350.1 - 1.3e-07 32.2 0.0 7e-05 23.3 0.1 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 KXT06350.1 - 2.6e-06 27.5 0.1 4.6e-05 23.4 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KXT06350.1 - 3.1e-06 27.4 0.0 1.1e-05 25.6 0.0 2.0 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KXT06350.1 - 8.2e-06 25.6 0.0 1.8e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KXT06350.1 - 0.00022 21.5 0.1 0.0042 17.4 0.1 2.6 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 KXT06350.1 - 0.00043 19.5 0.0 0.00091 18.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 KXT06350.1 - 0.0011 19.5 0.0 0.0031 18.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KXT06350.1 - 0.0014 18.2 0.0 0.0028 17.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 KXT06350.1 - 0.0023 17.2 0.0 0.005 16.1 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain TsaE PF02367.17 KXT06350.1 - 0.0031 17.5 0.1 0.011 15.7 0.0 1.9 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 KXT06350.1 - 0.0034 16.8 0.0 0.0088 15.5 0.0 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KXT06350.1 - 0.0044 17.2 0.0 0.012 15.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KXT06350.1 - 0.0068 16.2 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 KXT06350.1 - 0.0069 16.8 0.0 0.014 15.8 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 KXT06350.1 - 0.0084 16.1 0.0 0.02 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 KXT06350.1 - 0.0093 15.7 0.0 0.038 13.7 0.0 2.0 1 1 1 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.11 KXT06350.1 - 0.015 15.1 0.0 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KXT06350.1 - 0.025 14.3 0.0 0.068 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain Prot_ATP_OB_N PF17758.1 KXT06350.1 - 0.038 13.6 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain ATPase PF06745.13 KXT06350.1 - 0.039 13.3 0.0 0.16 11.3 0.0 2.0 2 0 0 2 2 2 0 KaiC eIF-1a PF01176.19 KXT06350.1 - 0.042 13.6 0.1 0.077 12.8 0.1 1.4 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 AAA_30 PF13604.6 KXT06350.1 - 0.051 13.3 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KXT06350.1 - 0.063 13.1 0.1 0.3 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KXT06350.1 - 0.066 13.1 0.1 0.17 11.8 0.0 1.7 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.16 KXT06350.1 - 0.075 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.6 KXT06350.1 - 0.086 13.1 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KXT06350.1 - 0.11 12.1 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KXT06350.1 - 0.13 11.5 0.6 0.3 10.3 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin Parvo_NS1 PF01057.17 KXT06350.1 - 0.15 11.2 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 LSM PF01423.22 KXT06352.1 - 2.2e-16 59.3 0.1 3.1e-16 58.8 0.1 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KXT06352.1 - 0.036 13.7 0.0 0.055 13.1 0.0 1.2 1 0 0 1 1 1 0 Hfq protein DUF4407 PF14362.6 KXT06354.1 - 0.26 10.6 8.8 0.47 9.7 8.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 KXT06354.1 - 0.76 9.3 11.2 1.8 8.1 11.2 1.7 1 0 0 1 1 1 0 Exonuclease VII, large subunit Leu_zip PF15294.6 KXT06354.1 - 0.84 9.1 14.6 1.3 8.5 13.8 1.7 1 1 0 1 1 1 0 Leucine zipper TMF_DNA_bd PF12329.8 KXT06354.1 - 4.2 7.4 11.8 0.97 9.5 4.2 2.9 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Arylsulfotran_2 PF14269.6 KXT06355.1 - 4.7e-30 105.0 0.3 6.9e-30 104.4 0.3 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KXT06355.1 - 5.4e-16 58.5 0.2 3.4e-14 52.6 0.2 2.2 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Proteasome PF00227.26 KXT06356.1 - 6.6e-29 100.8 0.0 8.6e-29 100.4 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit PI3_PI4_kinase PF00454.27 KXT06357.1 - 6.2e-40 137.6 0.0 9.7e-38 130.4 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KXT06357.1 - 3.6e-25 88.4 1.6 8e-25 87.3 0.4 2.2 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) ArfGap PF01412.18 KXT06358.1 - 5.9e-37 126.3 0.2 5.9e-37 126.3 0.2 2.3 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf UBA PF00627.31 KXT06358.1 - 0.00011 22.0 0.0 0.00024 20.9 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Mitoc_mL59 PF18126.1 KXT06359.1 - 1.2e-45 154.9 1.5 1.5e-45 154.6 1.5 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein mL59 HET PF06985.11 KXT06360.1 - 1.5e-06 28.6 0.0 2.5e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) F-box-like PF12937.7 KXT06361.1 - 2.8e-05 23.9 1.8 4.5e-05 23.3 0.4 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXT06361.1 - 0.0026 17.6 0.1 0.0074 16.1 0.1 1.7 1 0 0 1 1 1 1 F-box domain OPT PF03169.15 KXT06362.1 - 5.6e-169 563.7 47.4 6.4e-169 563.5 47.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein CFEM PF05730.11 KXT06363.1 - 2.7e-11 43.4 6.7 2.7e-11 43.4 6.7 2.0 3 0 0 3 3 3 1 CFEM domain WD40 PF00400.32 KXT06364.1 - 7.2e-10 39.3 0.0 1.2 10.2 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat Nucleoporin_N PF08801.11 KXT06364.1 - 0.00066 18.5 0.0 0.84 8.3 0.3 2.8 2 1 1 3 3 3 2 Nup133 N terminal like RSN1_7TM PF02714.15 KXT06365.1 - 3.7e-71 239.6 23.0 3.7e-71 239.6 23.0 1.5 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KXT06365.1 - 7.2e-40 137.1 0.0 1.4e-39 136.2 0.0 1.5 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 KXT06365.1 - 1.1e-37 129.2 0.1 1.1e-37 129.2 0.1 3.3 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport Anoctamin PF04547.12 KXT06365.1 - 0.73 8.6 10.2 0.013 14.3 2.2 2.0 2 0 0 2 2 2 0 Calcium-activated chloride channel 3Beta_HSD PF01073.19 KXT06366.1 - 1.3e-52 178.6 0.0 1.6e-52 178.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KXT06366.1 - 1.5e-34 119.5 0.0 2e-34 119.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXT06366.1 - 8.9e-15 54.9 0.0 2e-11 43.9 0.0 2.3 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KXT06366.1 - 2.2e-13 50.0 0.0 4.3e-07 29.4 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 KXT06366.1 - 5.8e-09 36.1 0.0 9.5e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KXT06366.1 - 1.5e-08 34.1 0.0 2e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KXT06366.1 - 6.7e-08 32.0 0.0 6.3e-07 28.8 0.0 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 KXT06366.1 - 6.6e-07 29.4 0.2 3.2e-06 27.2 0.2 1.9 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 KXT06366.1 - 8.8e-06 25.3 0.0 1.8e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT06366.1 - 0.00099 18.7 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.13 KXT06366.1 - 0.0081 15.7 0.0 0.033 13.8 0.0 1.8 1 1 0 1 1 1 1 NmrA-like family HCNGP PF07818.13 KXT06367.1 - 1.6e-23 83.1 0.7 8.2e-23 80.9 0.2 2.0 2 0 0 2 2 2 1 HCNGP-like protein HCNGP PF07818.13 KXT06368.1 - 1.6e-23 83.1 0.7 8.2e-23 80.9 0.2 2.0 2 0 0 2 2 2 1 HCNGP-like protein p450 PF00067.22 KXT06369.1 - 1.5e-55 188.8 0.0 2.6e-28 99.0 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.22 KXT06370.1 - 1.3e-48 165.9 0.0 6.9e-47 160.2 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Glyco_transf_34 PF05637.12 KXT06371.1 - 2.8e-14 53.4 0.0 9.9e-10 38.5 0.0 2.4 2 0 0 2 2 2 2 galactosyl transferase GMA12/MNN10 family HrcA PF01628.21 KXT06371.1 - 0.079 12.9 1.7 0.13 12.1 1.7 1.3 1 0 0 1 1 1 0 HrcA protein C terminal domain MIT PF04212.18 KXT06371.1 - 7.1 6.8 7.1 1 9.5 1.6 2.3 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain zf-C3HC4_3 PF13920.6 KXT06372.1 - 1.2e-05 25.1 9.6 1.2e-05 25.1 9.6 3.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) PRA1 PF03208.19 KXT06373.1 - 1.2e-36 125.5 1.4 1.6e-36 125.0 1.4 1.2 1 0 0 1 1 1 1 PRA1 family protein Zn_clus PF00172.18 KXT06374.1 - 3.5e-09 36.6 15.7 7.1e-09 35.7 15.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXT06374.1 - 1.1e-05 24.7 0.3 1.9e-05 23.8 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT06375.1 - 3.7e-09 36.6 15.7 7.7e-09 35.5 15.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXT06375.1 - 0.0012 18.0 0.3 0.0024 17.0 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain NTP_transf_3 PF12804.7 KXT06376.1 - 6.6e-05 23.3 0.0 0.00014 22.3 0.0 1.6 1 1 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 KXT06376.1 - 0.00054 19.6 7.6 0.0038 16.9 0.6 3.3 1 1 1 2 2 2 1 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 KXT06376.1 - 0.0012 18.5 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.6 KXT06376.1 - 0.079 12.7 4.6 0.19 11.5 0.9 2.9 3 0 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 KXT06376.1 - 0.27 9.3 1.3 1.6 6.8 0.5 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4954) NTP_transf_3 PF12804.7 KXT06377.1 - 6.6e-05 23.3 0.0 0.00014 22.3 0.0 1.6 1 1 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 KXT06377.1 - 0.00054 19.6 7.6 0.0038 16.9 0.6 3.3 1 1 1 2 2 2 1 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 KXT06377.1 - 0.0012 18.5 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.6 KXT06377.1 - 0.079 12.7 4.6 0.19 11.5 0.9 2.9 3 0 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 KXT06377.1 - 0.27 9.3 1.3 1.6 6.8 0.5 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4954) Myb_DNA-bind_6 PF13921.6 KXT06378.1 - 1.8e-11 44.1 3.1 1.8e-11 44.1 3.1 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain HSA PF07529.13 KXT06378.1 - 7e-11 42.3 8.5 7e-11 42.3 8.5 5.5 5 1 1 6 6 6 1 HSA Myb_DNA-binding PF00249.31 KXT06378.1 - 1.4 9.1 6.1 0.38 11.0 1.1 2.4 2 0 0 2 2 2 0 Myb-like DNA-binding domain Polyketide_cyc2 PF10604.9 KXT06383.1 - 0.00032 21.0 0.1 0.00074 19.8 0.1 1.5 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport zf-C2H2 PF00096.26 KXT06383.1 - 0.003 17.9 5.2 0.003 17.9 5.2 3.2 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KXT06383.1 - 0.0067 16.2 8.4 0.035 13.9 0.4 3.3 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 KXT06383.1 - 0.0099 16.6 4.1 0.0099 16.6 4.1 3.1 3 0 0 3 3 3 1 C2H2-type zinc finger Polyketide_cyc PF03364.20 KXT06383.1 - 0.044 14.0 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport zf-C2H2_jaz PF12171.8 KXT06383.1 - 0.086 13.2 2.1 0.31 11.4 2.1 2.0 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KXT06383.1 - 0.1 12.7 1.5 0.19 11.8 1.5 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXT06383.1 - 7.3 7.2 17.4 0.85 10.2 0.3 3.5 3 0 0 3 3 3 0 Zinc-finger double domain DnaJ PF00226.31 KXT06384.1 - 0.00015 21.8 0.2 0.00032 20.8 0.0 1.7 2 0 0 2 2 2 1 DnaJ domain Pam16 PF03656.13 KXT06384.1 - 0.00035 20.6 0.4 0.0012 18.9 0.4 1.7 1 1 0 1 1 1 1 Pam16 DUF3918 PF13056.6 KXT06384.1 - 0.035 13.7 1.1 0.035 13.7 1.1 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3918) Sulfatase PF00884.23 KXT06385.1 - 4.5e-57 193.8 0.0 5.9e-57 193.4 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.8 KXT06385.1 - 1.4e-24 85.6 3.5 1.4e-24 85.6 3.5 2.0 2 0 0 2 2 2 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.22 KXT06385.1 - 3.2e-11 43.4 0.0 1.3e-10 41.4 0.0 1.9 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KXT06385.1 - 0.0038 15.9 0.0 0.0063 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF4994 PF16385.5 KXT06385.1 - 0.013 15.4 0.1 1.2 9.0 0.1 2.5 1 1 1 2 2 2 0 Domain of unknown function Sulfatase_C PF14707.6 KXT06385.1 - 0.032 15.0 0.6 0.17 12.7 0.3 2.3 2 1 1 3 3 3 0 C-terminal region of aryl-sulfatase DUF1501 PF07394.12 KXT06385.1 - 0.047 12.7 0.0 0.077 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) MutS_V PF00488.21 KXT06386.1 - 4.4e-69 232.3 0.3 7e-69 231.6 0.3 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KXT06386.1 - 1.8e-39 135.9 0.0 4.4e-39 134.7 0.0 1.7 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KXT06386.1 - 1.8e-32 111.9 0.1 7.4e-32 109.9 0.1 2.1 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.18 KXT06386.1 - 3.2e-17 62.6 0.1 1.1e-16 61.0 0.1 2.0 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 KXT06386.1 - 7.9e-10 39.1 0.0 2.5e-09 37.5 0.0 1.9 1 0 0 1 1 1 1 MutS domain II AAA_29 PF13555.6 KXT06386.1 - 0.026 14.3 0.1 0.061 13.1 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KXT06386.1 - 0.04 14.4 3.2 0.13 12.7 0.4 2.7 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 KXT06386.1 - 0.068 13.0 0.1 0.19 11.5 0.1 1.8 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_27 PF13514.6 KXT06386.1 - 0.071 12.7 0.0 0.22 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain DGF-1_C PF11040.8 KXT06386.1 - 0.2 11.7 2.1 0.84 9.7 2.1 2.1 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Pil1 PF13805.6 KXT06387.1 - 7.1e-126 419.1 0.1 1e-125 418.6 0.1 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.11 KXT06387.1 - 0.049 13.0 2.6 0.054 12.9 0.9 1.7 1 1 0 2 2 2 0 FAM92 protein Acetyltransf_3 PF13302.7 KXT06388.1 - 3.6e-19 69.8 0.2 4.8e-19 69.4 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXT06388.1 - 1.8e-05 25.0 0.0 2.2e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 KXT06388.1 - 0.0011 18.7 0.0 0.0021 17.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Frataxin_Cyay PF01491.16 KXT06388.1 - 0.18 11.9 0.0 0.25 11.4 0.0 1.2 1 0 0 1 1 1 0 Frataxin-like domain DUF3431 PF11913.8 KXT06389.1 - 6.4e-71 238.5 0.7 8.4e-71 238.2 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) NMT1_2 PF13379.6 KXT06389.1 - 0.13 12.0 0.1 0.19 11.4 0.1 1.2 1 0 0 1 1 1 0 NMT1-like family Ribosomal_S11 PF00411.19 KXT06390.1 - 0.00018 21.9 2.0 0.0013 19.1 0.3 2.2 1 1 1 2 2 2 1 Ribosomal protein S11 NDUFB11 PF17250.2 KXT06390.1 - 0.058 14.0 0.0 0.11 13.1 0.0 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase 11 kDa subunit UAA PF08449.11 KXT06391.1 - 3.2e-83 279.4 15.2 4.2e-83 279.0 15.2 1.0 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 KXT06391.1 - 4.3e-05 22.8 0.4 4.3e-05 22.8 0.4 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter EamA PF00892.20 KXT06391.1 - 0.047 13.9 29.3 0.43 10.7 6.8 3.9 3 1 1 4 4 4 0 EamA-like transporter family UAA PF08449.11 KXT06392.1 - 8.1e-85 284.7 16.0 1.1e-84 284.3 16.0 1.0 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 KXT06392.1 - 4.1e-05 22.9 0.4 4.1e-05 22.9 0.4 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter EamA PF00892.20 KXT06392.1 - 0.0019 18.4 30.1 0.43 10.8 6.8 4.3 3 1 0 4 4 4 3 EamA-like transporter family TPR_1 PF00515.28 KXT06393.1 - 9.2e-56 183.5 23.5 1.1e-08 34.5 0.0 10.8 11 1 0 11 11 10 9 Tetratricopeptide repeat TPR_2 PF07719.17 KXT06393.1 - 5.2e-51 166.7 16.2 1.4e-06 27.9 0.0 10.5 11 0 0 11 11 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 KXT06393.1 - 4.4e-40 132.5 17.2 3.3e-07 30.0 0.0 10.7 10 1 0 10 10 10 8 Tetratricopeptide repeat TPR_17 PF13431.6 KXT06393.1 - 1.5e-29 100.2 18.9 5.2e-05 23.3 0.1 11.0 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_11 PF13414.6 KXT06393.1 - 6.4e-28 96.2 23.3 9.8e-07 28.4 0.9 9.8 6 2 3 9 9 9 6 TPR repeat TPR_19 PF14559.6 KXT06393.1 - 6.8e-26 90.6 18.3 2.2e-06 28.1 0.1 8.1 6 2 2 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 KXT06393.1 - 6.8e-25 87.4 15.5 4.7e-06 27.2 0.0 7.0 6 1 0 7 7 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 KXT06393.1 - 2.6e-23 80.7 13.2 0.0002 21.9 0.0 9.4 4 3 6 10 10 10 6 Tetratricopeptide repeat TPR_12 PF13424.6 KXT06393.1 - 7.9e-22 77.3 18.6 2.5e-05 24.5 0.6 7.7 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_6 PF13174.6 KXT06393.1 - 2.2e-21 75.0 19.9 0.0026 18.3 0.0 10.0 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_7 PF13176.6 KXT06393.1 - 4.4e-20 70.2 11.4 0.0098 15.9 0.1 9.4 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_9 PF13371.6 KXT06393.1 - 8.8e-14 51.4 13.2 0.00062 19.9 0.1 6.7 3 2 5 8 8 8 5 Tetratricopeptide repeat ANAPC3 PF12895.7 KXT06393.1 - 9.4e-12 45.0 11.7 1.9e-08 34.4 1.8 3.8 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 KXT06393.1 - 1.6e-07 31.3 9.0 0.044 13.5 0.3 4.8 3 2 1 4 4 4 3 Tetratricopeptide repeat-like domain TPR_15 PF13429.6 KXT06393.1 - 2.6e-07 30.1 13.0 0.00055 19.2 1.8 5.7 1 1 3 4 4 4 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KXT06393.1 - 1.2e-05 25.2 0.1 0.39 10.8 0.0 4.5 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.6 KXT06393.1 - 0.00042 20.6 0.4 0.69 10.3 0.0 4.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KXT06393.1 - 0.0013 18.2 6.0 0.4 10.0 0.1 3.3 2 1 1 3 3 3 2 MalT-like TPR region BTAD PF03704.17 KXT06393.1 - 0.0035 17.8 13.5 0.24 11.8 0.1 4.4 4 0 0 4 4 4 2 Bacterial transcriptional activator domain ChAPs PF09295.10 KXT06393.1 - 0.0086 15.1 2.2 3.1 6.7 0.1 2.9 2 1 1 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) DUF2225 PF09986.9 KXT06393.1 - 0.027 14.2 2.5 1.5 8.5 0.0 3.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_10 PF13374.6 KXT06393.1 - 0.072 13.0 16.9 30 4.7 0.2 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 KXT06393.1 - 0.81 8.7 2.7 19 4.2 0.1 2.9 3 0 0 3 3 3 0 Coatomer WD associated region SNAP PF14938.6 KXT06393.1 - 1.4 8.2 17.5 26 4.1 1.6 5.0 2 1 3 5 5 5 0 Soluble NSF attachment protein, SNAP ANAPC4_WD40 PF12894.7 KXT06394.1 - 1.3e-07 31.8 0.0 0.0011 19.3 0.0 2.8 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXT06394.1 - 5.7e-06 27.0 7.4 1.7 9.6 0.1 6.0 6 0 0 6 6 6 2 WD domain, G-beta repeat YL1 PF05764.13 KXT06394.1 - 0.0092 16.1 5.7 0.014 15.6 5.7 1.2 1 0 0 1 1 1 1 YL1 nuclear protein Sigma70_ner PF04546.13 KXT06394.1 - 0.51 10.2 5.9 0.76 9.6 5.9 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region SPT6_acidic PF14632.6 KXT06394.1 - 0.81 10.3 12.5 1.6 9.4 12.5 1.4 1 0 0 1 1 1 0 Acidic N-terminal SPT6 CDC45 PF02724.14 KXT06394.1 - 5.6 5.1 7.5 7.9 4.6 7.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Cmc1 PF08583.10 KXT06396.1 - 0.0036 17.3 1.4 0.011 15.8 1.4 1.9 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like AT_hook PF02178.19 KXT06396.1 - 0.17 11.8 31.2 0.4 10.7 2.3 4.4 4 0 0 4 4 4 0 AT hook motif tRNA-synt_2 PF00152.20 KXT06397.1 - 1.6e-71 241.0 0.0 2.7e-71 240.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 KXT06397.1 - 9.6e-14 51.1 0.0 1.7e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA_anti-codon PF01336.25 KXT06397.1 - 1.8e-07 31.0 0.0 5e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KXT06397.1 - 0.00053 19.5 0.6 0.82 9.1 0.3 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) STI1 PF17830.1 KXT06397.1 - 0.15 12.0 0.2 1.2 9.1 0.0 2.2 2 0 0 2 2 2 0 STI1 domain RR_TM4-6 PF06459.12 KXT06397.1 - 1.7 8.4 7.3 3.8 7.2 7.3 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4407 PF14362.6 KXT06397.1 - 4.6 6.5 5.4 8 5.7 5.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) tRNA-synt_2 PF00152.20 KXT06398.1 - 1.6e-71 241.0 0.0 2.7e-71 240.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 KXT06398.1 - 9.6e-14 51.1 0.0 1.7e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA_anti-codon PF01336.25 KXT06398.1 - 1.8e-07 31.0 0.0 5e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KXT06398.1 - 0.00053 19.5 0.6 0.82 9.1 0.3 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) STI1 PF17830.1 KXT06398.1 - 0.15 12.0 0.2 1.2 9.1 0.0 2.2 2 0 0 2 2 2 0 STI1 domain RR_TM4-6 PF06459.12 KXT06398.1 - 1.7 8.4 7.3 3.8 7.2 7.3 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4407 PF14362.6 KXT06398.1 - 4.6 6.5 5.4 8 5.7 5.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Glyco_hydro_43 PF04616.14 KXT06399.1 - 1.7e-25 89.9 2.9 1e-24 87.3 2.9 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 HLH PF00010.26 KXT06400.1 - 2.2e-15 56.3 0.0 6.1e-15 54.9 0.0 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain BRO1 PF03097.18 KXT06400.1 - 0.012 14.5 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 BRO1-like domain Cnn_1N PF07989.11 KXT06400.1 - 0.037 14.2 1.1 0.037 14.2 1.1 1.9 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 RNase_E_G PF10150.9 KXT06400.1 - 0.054 12.9 1.0 0.086 12.2 1.0 1.2 1 0 0 1 1 1 0 Ribonuclease E/G family GIT_CC PF16559.5 KXT06400.1 - 0.068 13.1 0.3 0.068 13.1 0.3 2.8 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor YabA PF06156.13 KXT06400.1 - 0.17 12.6 1.0 0.44 11.2 1.0 1.7 1 0 0 1 1 1 0 Initiation control protein YabA ZapB PF06005.12 KXT06400.1 - 0.17 12.4 5.7 0.57 10.7 5.7 1.9 1 0 0 1 1 1 0 Cell division protein ZapB DUF4776 PF16003.5 KXT06400.1 - 0.29 10.1 3.8 0.42 9.5 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) HLH PF00010.26 KXT06401.1 - 2.2e-15 56.3 0.0 6.1e-15 54.9 0.0 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain BRO1 PF03097.18 KXT06401.1 - 0.012 14.5 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 BRO1-like domain Cnn_1N PF07989.11 KXT06401.1 - 0.037 14.2 1.1 0.037 14.2 1.1 1.9 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 RNase_E_G PF10150.9 KXT06401.1 - 0.054 12.9 1.0 0.086 12.2 1.0 1.2 1 0 0 1 1 1 0 Ribonuclease E/G family GIT_CC PF16559.5 KXT06401.1 - 0.068 13.1 0.3 0.068 13.1 0.3 2.8 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor YabA PF06156.13 KXT06401.1 - 0.17 12.6 1.0 0.44 11.2 1.0 1.7 1 0 0 1 1 1 0 Initiation control protein YabA ZapB PF06005.12 KXT06401.1 - 0.17 12.4 5.7 0.57 10.7 5.7 1.9 1 0 0 1 1 1 0 Cell division protein ZapB DUF4776 PF16003.5 KXT06401.1 - 0.29 10.1 3.8 0.42 9.5 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) SGL PF08450.12 KXT06402.1 - 7.3e-62 209.2 0.1 1e-61 208.6 0.1 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Aldedh PF00171.22 KXT06403.1 - 9.7e-167 555.1 0.0 1.1e-166 554.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KXT06403.1 - 0.0034 16.9 0.0 0.017 14.6 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) Aldedh PF00171.22 KXT06404.1 - 9.7e-167 555.1 0.0 1.1e-166 554.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KXT06404.1 - 0.0034 16.9 0.0 0.017 14.6 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) Cupin_1 PF00190.22 KXT06405.1 - 2.9e-34 117.9 0.2 1.6e-17 63.5 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 KXT06405.1 - 3.3e-22 78.0 0.6 2.4e-11 43.2 0.1 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KXT06405.1 - 4.9e-09 35.8 0.2 0.00059 19.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 KXT06405.1 - 0.0033 17.3 0.0 1.7 8.6 0.0 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_6 PF12852.7 KXT06405.1 - 0.12 12.1 0.0 14 5.3 0.0 2.2 2 0 0 2 2 2 0 Cupin Cupin_1 PF00190.22 KXT06410.1 - 2.9e-34 117.9 0.2 1.6e-17 63.5 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 KXT06410.1 - 3.3e-22 78.0 0.6 2.4e-11 43.2 0.1 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KXT06410.1 - 4.9e-09 35.8 0.2 0.00059 19.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 KXT06410.1 - 0.0033 17.3 0.0 1.7 8.6 0.0 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_6 PF12852.7 KXT06410.1 - 0.12 12.1 0.0 14 5.3 0.0 2.2 2 0 0 2 2 2 0 Cupin Cupin_1 PF00190.22 KXT06411.1 - 6.2e-34 116.8 0.1 1.7e-17 63.5 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 KXT06411.1 - 3.5e-22 77.9 0.6 2.5e-11 43.1 0.1 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KXT06411.1 - 5.2e-09 35.7 0.2 0.00061 19.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 KXT06411.1 - 0.0037 17.2 0.0 1.8 8.5 0.0 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_6 PF12852.7 KXT06411.1 - 0.14 11.9 0.0 17 5.0 0.0 2.2 2 0 0 2 2 2 0 Cupin Prefoldin PF02996.17 KXT06413.1 - 1.8e-23 82.7 0.4 2.9e-23 82.1 0.4 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 KXT06413.1 - 0.00012 22.0 4.7 0.014 15.3 0.2 2.5 3 0 0 3 3 3 2 Prefoldin subunit PHM7_cyt PF14703.6 KXT06413.1 - 0.06 13.6 0.1 0.16 12.2 0.1 1.7 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Cep57_MT_bd PF06657.13 KXT06413.1 - 0.094 13.2 1.4 0.12 12.8 0.3 1.7 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Fib_alpha PF08702.10 KXT06413.1 - 0.11 12.7 2.2 3.7 7.7 0.0 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family TMF_TATA_bd PF12325.8 KXT06413.1 - 0.16 12.2 3.1 0.51 10.6 0.8 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding SHE3 PF17078.5 KXT06413.1 - 0.3 10.8 3.6 11 5.7 0.3 2.3 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 DUF1664 PF07889.12 KXT06413.1 - 0.32 11.0 5.0 0.36 10.9 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Mod_r PF07200.13 KXT06413.1 - 0.47 10.6 5.8 0.12 12.5 2.3 1.7 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Fungal_trans PF04082.18 KXT06414.1 - 1.9e-15 56.6 0.0 4e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT06414.1 - 2.2e-09 37.3 9.4 3.6e-09 36.6 9.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXT06415.1 - 1.9e-15 56.6 0.0 4e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT06415.1 - 2.2e-09 37.3 9.4 3.6e-09 36.6 9.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Leo1 PF04004.13 KXT06416.1 - 2.1e-40 138.3 0.1 4.3e-40 137.3 0.1 1.5 1 0 0 1 1 1 1 Leo1-like protein LPD30 PF18850.1 KXT06416.1 - 0.36 10.6 1.4 0.7 9.7 1.4 1.5 1 0 0 1 1 1 0 Large polyvalent protein associated domain 30 Ank_2 PF12796.7 KXT06418.1 - 4.3e-23 81.7 0.3 9.1e-06 26.2 0.0 6.5 5 2 1 6 6 6 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXT06418.1 - 3.7e-20 69.9 7.2 0.014 15.9 0.0 10.1 11 1 1 12 12 12 6 Ankyrin repeat Ank_5 PF13857.6 KXT06418.1 - 2.9e-16 59.3 5.9 3.8e-05 23.9 0.0 7.3 6 1 1 7 7 7 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KXT06418.1 - 7.2e-12 45.6 4.0 0.1 13.2 0.0 7.4 4 1 4 8 8 8 4 Ankyrin repeats (many copies) Ank PF00023.30 KXT06418.1 - 1.4e-08 34.8 10.2 0.0084 16.5 0.0 7.1 7 1 0 7 7 7 2 Ankyrin repeat F-box-like PF12937.7 KXT06418.1 - 0.003 17.4 0.1 0.0071 16.2 0.1 1.7 1 0 0 1 1 1 1 F-box-like Questin_oxidase PF14027.6 KXT06419.1 - 5.9e-92 308.8 1.0 7.3e-92 308.5 1.0 1.1 1 0 0 1 1 1 1 Questin oxidase-like GST_N_3 PF13417.6 KXT06420.1 - 1.9e-12 47.4 0.0 3.3e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXT06420.1 - 1.1e-11 44.9 0.0 1.9e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KXT06420.1 - 1.7e-11 44.1 0.0 3.4e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXT06420.1 - 2.7e-11 43.5 0.0 6.2e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KXT06420.1 - 1.8e-10 41.0 0.0 3.2e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXT06420.1 - 4.3e-07 29.9 0.1 8.6e-07 28.9 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GREB1 PF15782.5 KXT06421.1 - 0.87 6.6 7.2 0.87 6.6 7.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Ald_Xan_dh_C2 PF02738.18 KXT06422.1 - 4.8e-210 698.7 0.8 6.6e-210 698.2 0.8 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 KXT06422.1 - 3.2e-47 160.4 0.0 6.3e-47 159.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 KXT06422.1 - 4.5e-33 113.9 0.0 1.2e-32 112.5 0.0 1.8 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.17 KXT06422.1 - 9.4e-33 112.5 0.0 2.6e-32 111.0 0.0 1.8 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.20 KXT06422.1 - 3.2e-29 100.7 0.1 7.7e-29 99.5 0.1 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 KXT06422.1 - 1.1e-07 31.7 0.1 1.1e-07 31.7 0.1 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Sigma70_r3 PF04539.16 KXT06422.1 - 0.0081 16.2 0.3 0.16 12.1 0.0 2.5 2 0 0 2 2 2 1 Sigma-70 region 3 DUF218 PF02698.17 KXT06422.1 - 0.067 13.2 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 DUF218 domain SART-1 PF03343.13 KXT06423.1 - 1e-168 562.8 86.2 1e-168 562.8 86.2 1.5 2 0 0 2 2 2 1 SART-1 family MRG PF05712.13 KXT06423.1 - 6e-53 179.1 0.6 1.9e-52 177.5 0.0 2.1 2 0 0 2 2 2 1 MRG Tudor-knot PF11717.8 KXT06423.1 - 7e-08 32.2 4.0 8.8e-08 31.9 2.7 1.9 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Ribophorin_II PF05817.14 KXT06425.1 - 9.6e-32 110.3 0.0 1.2e-31 110.0 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II PufQ PF05398.11 KXT06425.1 - 0.087 13.0 0.1 0.52 10.5 0.0 2.1 2 0 0 2 2 2 0 PufQ cytochrome subunit Abhydrolase_6 PF12697.7 KXT06426.1 - 3.2e-07 31.2 0.0 4.3e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXT06426.1 - 0.01 15.2 0.1 0.035 13.4 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KXT06426.1 - 0.073 12.5 0.0 0.33 10.4 0.0 2.1 2 1 0 2 2 2 0 Prolyl oligopeptidase family HLH PF00010.26 KXT06427.1 - 7.5e-14 51.4 0.4 1.4e-13 50.6 0.4 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HLH PF00010.26 KXT06428.1 - 7.5e-14 51.4 0.4 1.4e-13 50.6 0.4 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HLH PF00010.26 KXT06429.1 - 7.5e-14 51.4 0.4 1.4e-13 50.6 0.4 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HLH PF00010.26 KXT06430.1 - 7.5e-14 51.4 0.4 1.4e-13 50.6 0.4 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HLH PF00010.26 KXT06431.1 - 7.5e-14 51.4 0.4 1.4e-13 50.6 0.4 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HLH PF00010.26 KXT06432.1 - 7.5e-14 51.4 0.4 1.4e-13 50.6 0.4 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain tRNA-synt_1b PF00579.25 KXT06433.1 - 2.6e-58 197.7 0.0 4.4e-58 196.9 0.0 1.3 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 KXT06433.1 - 9.8e-42 141.6 0.0 1.9e-41 140.7 0.0 1.5 1 0 0 1 1 1 1 Tyrosyl-tRNA synthetase C-terminal domain Tim44 PF04280.15 KXT06434.1 - 7e-34 117.0 1.9 9e-34 116.7 0.0 2.2 3 0 0 3 3 3 1 Tim44-like domain DUF1376 PF07120.11 KXT06434.1 - 3.4 8.0 4.9 43 4.5 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1376) His_Phos_1 PF00300.22 KXT06436.1 - 1e-30 106.9 0.2 1.6e-30 106.3 0.2 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_1 PF00300.22 KXT06437.1 - 1e-30 106.9 0.2 1.6e-30 106.3 0.2 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_1 PF00300.22 KXT06438.1 - 1e-30 106.9 0.2 1.6e-30 106.3 0.2 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) HAD_2 PF13419.6 KXT06439.1 - 4.7e-07 30.0 0.0 3.1e-06 27.4 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KXT06439.1 - 0.0017 18.7 0.0 0.0027 18.0 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase EamA PF00892.20 KXT06440.1 - 2.6e-07 30.9 25.1 2.3e-06 27.8 1.5 3.0 3 0 0 3 3 3 2 EamA-like transporter family CSG2 PF16965.5 KXT06440.1 - 0.0044 16.0 6.2 0.048 12.6 6.3 2.0 1 1 0 1 1 1 1 Ceramide synthase regulator But2 PF09792.9 KXT06441.1 - 2.3e-43 148.0 0.4 2.3e-43 148.0 0.4 3.3 3 0 0 3 3 3 1 Ubiquitin 3 binding protein But2 C-terminal domain LRR_4 PF12799.7 KXT06442.1 - 0.0005 20.4 6.8 1.4 9.5 0.0 6.0 5 2 3 8 8 8 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KXT06442.1 - 0.044 14.3 3.6 8.9 7.3 0.0 5.3 7 0 0 7 7 7 0 Leucine Rich Repeat GATA PF00320.27 KXT06442.1 - 0.067 12.8 0.6 0.19 11.4 0.6 1.7 1 0 0 1 1 1 0 GATA zinc finger DUF4428 PF14471.6 KXT06442.1 - 0.089 12.7 0.2 0.26 11.2 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) LRR_8 PF13855.6 KXT06442.1 - 0.16 11.7 0.0 22 4.9 0.0 3.7 4 0 0 4 4 4 0 Leucine rich repeat CNDH2_C PF16858.5 KXT06442.1 - 2.4 7.9 13.4 4.8 7.0 13.4 1.4 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DTHCT PF08070.11 KXT06442.1 - 2.7 8.8 39.5 0.53 11.1 30.7 2.8 2 1 1 3 3 3 0 DTHCT (NUC029) region HSP70 PF00012.20 KXT06443.1 - 3e-13 48.9 0.0 9.5e-12 43.9 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein FtsA PF14450.6 KXT06443.1 - 0.0022 18.4 0.2 0.073 13.5 0.0 2.5 2 0 0 2 2 2 1 Cell division protein FtsA S-methyl_trans PF02574.16 KXT06445.1 - 1e-74 251.8 0.0 1.2e-74 251.6 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase EMP24_GP25L PF01105.24 KXT06446.1 - 1.4e-47 162.0 0.0 1.6e-47 161.8 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4793 PF16041.5 KXT06446.1 - 0.057 13.6 0.0 0.13 12.4 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4793) RWD PF05773.22 KXT06449.1 - 1.5e-24 86.5 2.6 2.9e-24 85.6 2.6 1.5 1 0 0 1 1 1 1 RWD domain Myb_DNA-bind_2 PF08914.11 KXT06449.1 - 0.012 15.8 0.5 0.012 15.8 0.5 2.4 3 0 0 3 3 3 0 Rap1 Myb domain ketoacyl-synt PF00109.26 KXT06449.1 - 0.054 13.1 0.2 0.079 12.5 0.2 1.2 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain DFRP_C PF16543.5 KXT06449.1 - 1.7 9.2 15.9 3.3 8.3 14.4 2.3 1 1 1 2 2 2 0 DRG Family Regulatory Proteins, Tma46 PTCB-BRCT PF12738.7 KXT06450.1 - 5.8e-31 106.2 2.3 7.4e-22 77.1 0.3 4.7 4 0 0 4 4 4 3 twin BRCT domain RTT107_BRCT_5 PF16770.5 KXT06450.1 - 2.4e-25 88.3 0.1 1.5e-23 82.5 0.0 3.5 4 0 0 4 4 4 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 KXT06450.1 - 2.3e-23 82.4 0.0 0.0052 17.2 0.1 5.6 5 0 0 5 5 5 5 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KXT06450.1 - 2.2e-22 79.2 0.0 3.8e-09 36.8 0.2 6.3 6 1 0 6 6 6 4 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KXT06450.1 - 9e-11 41.9 4.9 0.0082 16.4 0.0 5.1 5 0 0 5 5 5 3 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 KXT06450.1 - 2.5e-06 27.5 0.2 1.2 9.2 0.1 4.4 4 0 0 4 4 4 2 BRCA1 C Terminus (BRCT) domain NIBRIN_BRCT_II PF16508.5 KXT06450.1 - 0.015 15.6 0.0 2.2 8.7 0.0 3.6 3 1 0 3 3 3 0 Second BRCT domain on Nijmegen syndrome breakage protein AT_hook PF02178.19 KXT06450.1 - 0.17 11.9 2.3 0.59 10.2 2.3 2.0 1 0 0 1 1 1 0 AT hook motif Sen15 PF09631.10 KXT06451.1 - 8.6e-21 74.1 0.0 6.2e-20 71.4 0.0 2.0 1 1 0 1 1 1 1 Sen15 protein ATP-synt_10 PF05176.14 KXT06452.1 - 3.5e-71 239.5 0.0 4.3e-71 239.2 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein DUF1657 PF07870.11 KXT06452.1 - 0.03 14.2 0.0 0.068 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1657) EzrA PF06160.12 KXT06453.1 - 0.024 12.8 0.7 0.039 12.1 0.1 1.5 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Syntaxin-6_N PF09177.11 KXT06453.1 - 0.028 15.0 0.1 0.74 10.4 0.1 2.6 2 0 0 2 2 2 0 Syntaxin 6, N-terminal CLZ PF16526.5 KXT06453.1 - 0.11 12.9 0.9 0.92 9.9 0.0 2.4 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FlaC_arch PF05377.11 KXT06453.1 - 0.15 12.5 0.6 33 5.0 0.0 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) TolA_bind_tri PF16331.5 KXT06453.1 - 0.44 10.7 5.1 8.7 6.5 1.7 2.5 2 0 0 2 2 2 0 TolA binding protein trimerisation Aa_trans PF01490.18 KXT06454.1 - 3.2e-27 95.3 21.3 4.6e-27 94.8 21.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PKD_3 PF16820.5 KXT06454.1 - 0.028 14.1 0.0 0.061 13.1 0.0 1.5 1 0 0 1 1 1 0 PKD-like domain Pox_A14 PF05767.12 KXT06454.1 - 3.1 8.0 4.9 1.3 9.3 0.3 2.7 2 1 1 3 3 3 0 Poxvirus virion envelope protein A14 Aldo_ket_red PF00248.21 KXT06455.1 - 4.6e-50 170.5 0.0 5.3e-50 170.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family T2SSF PF00482.23 KXT06456.1 - 0.0095 15.9 0.6 0.026 14.5 0.4 1.8 1 1 1 2 2 2 1 Type II secretion system (T2SS), protein F DUF2207 PF09972.9 KXT06456.1 - 0.011 14.5 2.4 0.02 13.7 2.4 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) RIFIN PF02009.16 KXT06456.1 - 0.038 13.9 5.9 0.07 13.0 5.0 1.7 1 1 1 2 2 2 0 Rifin DUF2935 PF11155.8 KXT06456.1 - 0.075 13.4 1.8 0.46 10.8 1.8 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) DUF3040 PF11239.8 KXT06456.1 - 0.11 12.8 0.1 0.32 11.3 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) FUSC PF04632.12 KXT06456.1 - 0.25 9.9 6.1 0.16 10.5 4.0 1.7 1 1 1 2 2 2 0 Fusaric acid resistance protein family DUF2115 PF09888.9 KXT06456.1 - 0.25 11.8 4.7 0.094 13.2 1.0 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) TMEM154 PF15102.6 KXT06456.1 - 0.27 11.2 0.0 0.27 11.2 0.0 2.0 2 1 0 2 2 2 0 TMEM154 protein family Synaptobrevin PF00957.21 KXT06456.1 - 0.49 10.2 5.7 0.85 9.4 0.5 2.6 2 0 0 2 2 2 0 Synaptobrevin Renin_r PF07850.14 KXT06456.1 - 0.66 10.6 2.6 1.3 9.7 0.2 2.5 2 0 0 2 2 2 0 Renin receptor-like protein DUF2721 PF11026.8 KXT06456.1 - 2.5 8.0 9.6 0.13 12.2 0.8 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) MCU PF04678.13 KXT06456.1 - 3.4 7.7 13.4 3.4e+02 1.2 13.4 2.6 1 1 0 1 1 1 0 Mitochondrial calcium uniporter DUF1664 PF07889.12 KXT06456.1 - 8.9 6.4 6.7 5.8 7.0 2.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Cas_CXXC_CXXC PF09706.10 KXT06458.1 - 0.034 14.4 0.2 0.085 13.1 0.2 1.6 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_CXXC_CXXC) Pro_CA PF00484.19 KXT06459.1 - 8.1e-13 49.0 0.3 2.5e-11 44.1 0.3 2.3 1 1 0 1 1 1 1 Carbonic anhydrase bZIP_2 PF07716.15 KXT06461.1 - 4.9e-05 23.3 7.3 0.00011 22.2 7.3 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KXT06461.1 - 0.051 14.1 2.7 0.12 12.9 2.7 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_1 PF00170.21 KXT06461.1 - 0.81 9.8 6.8 0.28 11.3 3.7 1.7 2 0 0 2 2 2 0 bZIP transcription factor RRM_1 PF00076.22 KXT06463.1 - 3.5e-17 62.0 0.0 4.9e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KXT06463.1 - 0.0002 21.4 0.0 0.0003 20.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif Limkain-b1 PF11608.8 KXT06463.1 - 0.12 12.5 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Limkain b1 Rxt3 PF08642.10 KXT06465.1 - 1.2e-33 116.6 0.0 4.5e-33 114.7 0.0 2.1 1 0 0 1 1 1 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 KXT06465.1 - 1.7e-05 24.8 0.0 4.7e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 LCCL domain CUB_2 PF02408.20 KXT06465.1 - 0.21 11.3 0.0 0.58 9.9 0.0 1.7 1 0 0 1 1 1 0 CUB-like domain Carb_kinase PF01256.17 KXT06466.1 - 8.4e-58 195.7 0.1 1.1e-57 195.4 0.1 1.1 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.15 KXT06466.1 - 0.00062 19.2 0.0 0.00099 18.6 0.0 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Phos_pyr_kin PF08543.12 KXT06466.1 - 0.00092 18.7 0.1 0.0024 17.3 0.1 1.7 1 1 1 2 2 2 1 Phosphomethylpyrimidine kinase zf-C3HC4_2 PF13923.6 KXT06467.1 - 2.9e-09 36.6 2.5 7.1e-09 35.4 2.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXT06467.1 - 5.1e-09 36.3 4.4 1.4e-08 34.9 4.4 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KXT06467.1 - 9.3e-08 31.8 2.8 2.2e-07 30.7 2.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXT06467.1 - 7.8e-07 29.0 0.6 1.9e-06 27.8 0.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KXT06467.1 - 1.4e-06 28.0 4.1 4.2e-06 26.5 4.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KXT06467.1 - 1.8e-06 28.1 6.6 4e-06 27.0 6.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KXT06467.1 - 4.9e-06 26.4 4.6 1.1e-05 25.2 4.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KXT06467.1 - 6.8e-05 23.0 2.9 0.00015 21.9 2.9 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KXT06467.1 - 0.00023 21.0 3.6 0.00023 21.0 3.6 1.9 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KXT06467.1 - 0.039 14.0 1.5 0.083 12.9 1.5 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger TAP35_44 PF07265.11 KXT06467.1 - 0.041 13.9 1.1 0.081 13.0 1.1 1.4 1 0 0 1 1 1 0 Tapetum specific protein TAP35/TAP44 zf-RING_4 PF14570.6 KXT06467.1 - 0.11 12.2 4.1 0.32 10.8 4.1 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 KXT06467.1 - 0.28 11.0 2.6 0.56 10.1 2.6 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF3587 PF12132.8 KXT06467.1 - 0.3 10.5 2.6 0.56 9.6 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3587) zf-P11 PF03854.14 KXT06467.1 - 2.3 7.9 7.6 0.37 10.5 1.5 2.6 3 0 0 3 3 3 0 P-11 zinc finger Cutinase PF01083.22 KXT06468.1 - 8.1e-38 130.2 3.8 1.1e-37 129.8 3.8 1.2 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.20 KXT06468.1 - 0.011 15.4 0.1 0.017 14.8 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PE-PPE PF08237.11 KXT06468.1 - 0.011 15.2 0.5 0.017 14.7 0.5 1.2 1 0 0 1 1 1 0 PE-PPE domain Thioesterase PF00975.20 KXT06468.1 - 0.36 10.9 0.1 0.36 10.9 0.1 1.5 2 0 0 2 2 2 0 Thioesterase domain Cutinase PF01083.22 KXT06469.1 - 8.1e-38 130.2 3.8 1.1e-37 129.8 3.8 1.2 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.20 KXT06469.1 - 0.011 15.4 0.1 0.017 14.8 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PE-PPE PF08237.11 KXT06469.1 - 0.011 15.2 0.5 0.017 14.7 0.5 1.2 1 0 0 1 1 1 0 PE-PPE domain Thioesterase PF00975.20 KXT06469.1 - 0.36 10.9 0.1 0.36 10.9 0.1 1.5 2 0 0 2 2 2 0 Thioesterase domain Cgr1 PF03879.14 KXT06470.1 - 1.8e-32 111.9 27.2 2.1e-32 111.7 27.2 1.0 1 0 0 1 1 1 1 Cgr1 family Tox-ART-HYE1 PF15634.6 KXT06470.1 - 0.027 13.8 2.1 0.03 13.6 2.1 1.0 1 0 0 1 1 1 0 HYE1 signature containing ADP-ribosyltransferase Prismane PF03063.20 KXT06470.1 - 0.21 10.2 4.2 0.24 10.0 4.2 1.0 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family AAA_11 PF13086.6 KXT06470.1 - 0.8 9.4 13.2 0.83 9.4 13.2 1.0 1 0 0 1 1 1 0 AAA domain Mobilization_B PF17511.2 KXT06470.1 - 1.1 9.6 6.0 6.3 7.2 4.8 1.9 1 1 1 2 2 2 0 Mobilization protein B HicA_toxin PF07927.12 KXT06473.1 - 0.00017 21.5 0.0 0.00034 20.6 0.0 1.6 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, Ferric_reduct PF01794.19 KXT06474.1 - 8.8e-22 77.5 9.6 2.7e-21 76.0 9.3 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KXT06474.1 - 1.2e-17 64.5 0.0 1.6e-11 44.6 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KXT06474.1 - 8.4e-15 54.8 0.0 8.5e-11 41.9 0.0 2.3 2 0 0 2 2 2 2 FAD-binding domain Serglycin PF04360.12 KXT06475.1 - 0.83 9.6 5.6 0.39 10.7 3.3 1.6 2 0 0 2 2 2 0 Serglycin PTH2 PF01981.16 KXT06476.1 - 2.9e-48 163.0 0.2 3.6e-48 162.7 0.2 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Corona_nucleoca PF00937.18 KXT06476.1 - 0.05 12.6 0.0 0.064 12.3 0.0 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein TauD PF02668.16 KXT06477.1 - 2.2e-61 208.0 0.5 2.7e-61 207.7 0.5 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Ribosomal_L24e PF01246.20 KXT06478.1 - 4.6e-32 110.1 6.6 4.6e-32 110.1 6.6 1.8 3 0 0 3 3 3 1 Ribosomal protein L24e Ribosomal_L24e PF01246.20 KXT06479.1 - 4.6e-32 110.1 6.6 4.6e-32 110.1 6.6 1.8 3 0 0 3 3 3 1 Ribosomal protein L24e Zip PF02535.22 KXT06480.1 - 9e-63 212.5 0.5 1.2e-62 212.1 0.5 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter adh_short PF00106.25 KXT06481.1 - 1.7e-21 76.6 0.1 7.8e-21 74.4 0.3 1.8 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.10 KXT06481.1 - 3.4e-10 40.1 0.2 5.2e-10 39.5 0.2 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KXT06481.1 - 7.1e-10 38.8 0.0 3.4e-09 36.6 0.1 1.8 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 KXT06481.1 - 0.0008 18.6 0.2 0.0011 18.1 0.2 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KXT06481.1 - 0.021 14.0 0.9 0.53 9.4 0.9 2.2 1 1 0 1 1 1 0 Male sterility protein Sacchrp_dh_NADP PF03435.18 KXT06481.1 - 0.047 13.9 0.1 0.08 13.2 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KXT06481.1 - 0.083 12.9 0.3 0.17 11.9 0.3 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PIR PF00399.19 KXT06482.1 - 4.7e-18 64.2 55.7 5.9e-07 28.9 2.4 6.8 6 1 1 7 7 7 6 Yeast PIR protein repeat MRP-S31 PF15433.6 KXT06484.1 - 0.016 14.9 6.5 0.02 14.6 6.5 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Selenoprotein_S PF06936.11 KXT06484.1 - 0.79 9.5 13.5 1.6 8.5 13.2 1.6 1 1 0 1 1 1 0 Selenoprotein S (SelS) Presenilin PF01080.17 KXT06484.1 - 6.8 5.3 7.2 8.6 5.0 7.2 1.2 1 0 0 1 1 1 0 Presenilin CN_hydrolase PF00795.22 KXT06485.1 - 4.5e-59 199.9 0.0 5e-59 199.8 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Neugrin PF06413.11 KXT06486.1 - 2.9e-11 43.8 0.3 2.9e-11 43.8 0.3 3.2 2 2 0 3 3 3 1 Neugrin MRP-L20 PF12824.7 KXT06486.1 - 1.4e-08 35.0 0.5 1.4e-08 35.0 0.5 4.2 2 1 1 3 3 3 1 Mitochondrial ribosomal protein subunit L20 V_ATPase_I PF01496.19 KXT06486.1 - 9.8 3.9 7.6 14 3.4 7.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family adh_short_C2 PF13561.6 KXT06488.1 - 3.9e-55 187.0 2.8 4.2e-53 180.3 2.8 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXT06488.1 - 1.3e-41 142.2 3.5 1.3e-38 132.5 3.5 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXT06488.1 - 2e-11 44.1 4.9 1.5e-09 38.0 4.9 2.2 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KXT06488.1 - 0.032 14.1 0.9 0.086 12.7 0.9 1.7 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ACCA PF03255.14 KXT06488.1 - 0.065 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Epimerase PF01370.21 KXT06488.1 - 0.13 11.7 0.1 1.2 8.5 0.1 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Phosphodiest PF01663.22 KXT06489.1 - 3.5e-89 299.9 0.4 4.5e-89 299.5 0.4 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KXT06489.1 - 3.4e-05 23.4 0.0 0.0045 16.4 0.0 2.2 2 0 0 2 2 2 2 Sulfatase Mito_carr PF00153.27 KXT06491.1 - 7.5e-63 208.5 0.4 2.6e-21 75.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein MFS_1 PF07690.16 KXT06492.1 - 1.4e-15 57.1 64.6 3.7e-14 52.4 36.4 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily Oxidored_q2 PF00420.24 KXT06492.1 - 0.07 12.8 2.2 0.8 9.4 2.1 2.7 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L SRA1 PF07304.11 KXT06494.1 - 4.1e-09 36.4 0.2 4.1e-09 36.4 0.2 3.4 3 0 0 3 3 3 1 Steroid receptor RNA activator (SRA1) ANAPC4_WD40 PF12894.7 KXT06494.1 - 4.4e-07 30.1 1.3 0.007 16.6 0.0 4.0 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXT06494.1 - 5.1e-06 27.1 6.2 0.92 10.5 0.1 5.5 6 0 0 6 6 6 2 WD domain, G-beta repeat eIF2A PF08662.11 KXT06494.1 - 0.00014 21.8 0.6 0.0025 17.7 0.0 2.9 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Sec16_C PF12931.7 KXT06494.1 - 0.0002 21.1 1.1 0.0002 21.1 1.1 2.3 2 1 0 2 2 2 1 Sec23-binding domain of Sec16 Prp18 PF02840.15 KXT06494.1 - 0.0038 17.3 0.9 0.04 14.0 0.0 2.4 2 0 0 2 2 2 1 Prp18 domain PALB2_WD40 PF16756.5 KXT06494.1 - 0.015 14.2 0.1 13 4.6 0.0 3.2 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain PRKCSH PF07915.13 KXT06495.1 - 2.6e-17 63.6 0.1 2.6e-17 63.6 0.1 2.5 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 KXT06495.1 - 0.011 15.5 0.1 0.041 13.6 0.0 2.0 2 0 0 2 2 2 0 Glucosidase II beta subunit-like protein SpoOE-like PF09388.10 KXT06495.1 - 0.23 11.4 0.9 0.8 9.7 0.1 2.3 3 0 0 3 3 3 0 Spo0E like sporulation regulatory protein Solute_trans_a PF03619.16 KXT06497.1 - 2.1e-56 191.4 10.3 2.6e-56 191.1 10.3 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Polysacc_synt_C PF14667.6 KXT06497.1 - 1.3 9.1 11.3 0.83 9.7 1.6 2.6 2 1 0 3 3 3 0 Polysaccharide biosynthesis C-terminal domain Peptidase_M49 PF03571.15 KXT06498.1 - 5.9e-240 797.3 0.0 7.1e-240 797.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 adh_short PF00106.25 KXT06499.1 - 1.7e-29 102.7 0.0 3.2e-29 101.8 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT06499.1 - 7e-20 71.6 0.0 1.3e-17 64.2 0.0 2.2 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT06499.1 - 1.2e-11 44.9 0.0 2.9e-11 43.6 0.0 1.6 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KXT06499.1 - 9.5e-06 25.6 0.3 1.7e-05 24.8 0.3 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 KXT06499.1 - 2.3e-05 23.8 0.0 3.7e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 KXT06499.1 - 0.00031 20.3 0.0 0.00054 19.5 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXT06499.1 - 0.0023 17.8 1.1 0.25 11.2 1.0 2.9 2 1 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KXT06499.1 - 0.0034 16.8 0.0 0.0046 16.4 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_7 PF13241.6 KXT06499.1 - 0.0045 17.4 0.2 0.0087 16.5 0.2 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding ADH_zinc_N PF00107.26 KXT06499.1 - 0.01 15.8 0.0 0.025 14.5 0.0 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NAD_binding_2 PF03446.15 KXT06499.1 - 0.016 15.4 0.0 0.031 14.5 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KXT06499.1 - 0.017 15.7 0.1 0.035 14.7 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 KXT06499.1 - 0.027 14.7 0.1 0.053 13.8 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Polysacc_synt_2 PF02719.15 KXT06499.1 - 0.034 13.3 0.0 0.044 12.9 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Amidase_3 PF01520.18 KXT06499.1 - 0.069 13.3 0.0 0.12 12.5 0.0 1.4 1 1 0 1 1 1 0 N-acetylmuramoyl-L-alanine amidase Helicase_RecD PF05127.14 KXT06499.1 - 0.081 12.8 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Helicase HAD_SAK_2 PF18143.1 KXT06499.1 - 0.098 13.0 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 HAD domain in Swiss Army Knife RNA repair proteins YjeF_N PF03853.15 KXT06499.1 - 0.098 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 YjeF-related protein N-terminus ApbA PF02558.16 KXT06499.1 - 0.12 12.1 0.1 0.21 11.2 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Fungal_trans PF04082.18 KXT06500.1 - 1.6e-27 96.2 0.0 2.6e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT06500.1 - 2e-09 37.4 10.9 3.2e-09 36.8 10.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FATC PF02260.20 KXT06500.1 - 0.11 12.4 0.5 0.26 11.1 0.1 2.0 2 1 0 2 2 2 0 FATC domain Vac_ImportDeg PF09783.9 KXT06501.1 - 3e-65 219.0 0.0 3.7e-65 218.7 0.0 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein V-SNARE_C PF12352.8 KXT06503.1 - 2.6e-13 50.0 0.3 2.6e-13 50.0 0.3 2.0 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Spc7 PF08317.11 KXT06503.1 - 0.036 13.0 11.0 0.025 13.5 9.4 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein Muted PF14942.6 KXT06503.1 - 0.6 10.4 9.3 2.4 8.5 5.6 2.3 1 1 0 2 2 2 0 Organelle biogenesis, Muted-like protein Exonuc_VII_L PF02601.15 KXT06503.1 - 0.63 9.6 8.2 0.81 9.2 8.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit FlgN PF05130.12 KXT06503.1 - 1.3 9.5 13.3 0.39 11.2 10.1 1.7 1 1 1 2 2 2 0 FlgN protein Syntaxin-6_N PF09177.11 KXT06503.1 - 1.5 9.4 8.9 0.35 11.4 5.1 1.9 2 1 0 2 2 2 0 Syntaxin 6, N-terminal SATase_N PF06426.14 KXT06503.1 - 1.6 9.1 7.1 19 5.7 7.1 2.4 1 1 0 1 1 1 0 Serine acetyltransferase, N-terminal HMG_box PF00505.19 KXT06504.1 - 1.9e-11 44.2 2.5 1.9e-11 44.2 2.5 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KXT06504.1 - 2.4 8.8 9.2 0.3 11.7 3.5 2.4 2 0 0 2 2 2 0 HMG-box domain HMG_box PF00505.19 KXT06505.1 - 1.8e-11 44.3 2.5 1.8e-11 44.3 2.5 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KXT06505.1 - 1.8 9.2 8.9 0.28 11.8 3.5 2.4 2 0 0 2 2 2 0 HMG-box domain Ras PF00071.22 KXT06506.1 - 1.5e-57 193.8 0.0 1.8e-57 193.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXT06506.1 - 3.6e-34 117.6 0.0 5.6e-34 116.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXT06506.1 - 2.4e-13 49.9 0.0 5e-13 48.9 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KXT06506.1 - 3.4e-07 29.9 0.0 4.3e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KXT06506.1 - 8.2e-07 28.8 0.0 1.2e-06 28.3 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KXT06506.1 - 0.0001 22.4 0.0 0.00019 21.5 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KXT06506.1 - 0.00054 20.4 0.0 0.00072 20.0 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KXT06506.1 - 0.011 15.6 0.1 3.5 7.5 0.0 2.6 2 1 0 2 2 2 0 RsgA GTPase 3Beta_HSD PF01073.19 KXT06507.1 - 7.7e-54 182.6 0.0 1.3e-53 181.8 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KXT06507.1 - 7.1e-28 97.7 0.1 1e-27 97.2 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXT06507.1 - 3.9e-16 59.4 0.1 2.3e-13 50.3 0.1 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KXT06507.1 - 6.8e-15 54.9 0.2 4.9e-10 39.0 0.1 2.2 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 KXT06507.1 - 5.4e-12 45.4 0.0 1e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KXT06507.1 - 1.3e-08 34.4 0.4 1.1e-07 31.3 0.4 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KXT06507.1 - 1.9e-08 34.4 0.0 3.1e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KXT06507.1 - 2.8e-05 23.8 0.1 5.3e-05 22.9 0.1 1.4 1 1 0 1 1 1 1 NmrA-like family KR PF08659.10 KXT06507.1 - 6.5e-05 22.9 1.0 0.0011 18.9 1.0 2.4 1 1 0 1 1 1 1 KR domain FtsJ PF01728.19 KXT06507.1 - 0.031 14.4 0.0 0.052 13.7 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Ldh_1_N PF00056.23 KXT06507.1 - 0.095 12.8 0.0 0.23 11.5 0.0 1.8 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Esterase_phd PF10503.9 KXT06508.1 - 0.0097 15.4 0.1 0.068 12.6 0.0 2.3 3 0 0 3 3 3 1 Esterase PHB depolymerase Abhydrolase_2 PF02230.16 KXT06508.1 - 0.026 14.3 0.0 0.043 13.6 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KXT06508.1 - 0.11 12.0 0.1 0.42 10.0 0.1 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF987 PF06174.11 KXT06508.1 - 0.14 12.1 0.0 0.49 10.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF987) Pkinase PF00069.25 KXT06509.1 - 7.6e-17 61.5 0.0 9.7e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT06509.1 - 2.9e-16 59.6 0.0 1.3e-15 57.4 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXT06509.1 - 0.0006 19.2 0.0 0.00095 18.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.9 KXT06509.1 - 0.21 11.1 0.0 0.32 10.5 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL 14-3-3 PF00244.20 KXT06511.1 - 9.6e-09 35.1 1.5 1.3e-08 34.7 0.0 1.7 2 0 0 2 2 2 1 14-3-3 protein DUF3665 PF12427.8 KXT06512.1 - 0.24 11.1 0.9 0.62 9.8 0.9 1.7 1 0 0 1 1 1 0 Branched-chain amino acid aminotransferase Trs65 PF12735.7 KXT06513.1 - 2.3e-40 138.9 0.1 4.5e-40 138.0 0.1 1.4 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 Glyco_hydro_3_C PF01915.22 KXT06514.1 - 1.1e-39 136.5 0.0 3e-39 135.1 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KXT06514.1 - 4.6e-39 134.7 0.0 4.4e-38 131.4 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KXT06514.1 - 1.8e-20 72.8 0.0 3.4e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain NFACT-R_1 PF05670.13 KXT06515.1 - 1.1e-38 132.2 0.0 1.7e-38 131.6 0.0 1.3 1 0 0 1 1 1 1 NFACT protein RNA binding domain Nexin_C PF08628.12 KXT06515.1 - 0.13 12.9 3.3 0.26 11.9 3.2 1.6 1 1 0 1 1 1 0 Sorting nexin C terminal Myb_DNA-bind_6 PF13921.6 KXT06516.1 - 4.4e-12 46.1 18.8 1e-08 35.3 0.1 4.3 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KXT06516.1 - 2.1e-07 31.0 17.3 5.6e-05 23.2 0.4 4.4 4 0 0 4 4 4 2 Myb-like DNA-binding domain HTH_AsnC-type PF13404.6 KXT06516.1 - 0.011 15.5 0.0 0.4 10.5 0.0 3.0 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain MADF_DNA_bdg PF10545.9 KXT06516.1 - 0.056 13.8 0.5 0.056 13.8 0.5 3.6 2 1 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Rap1_C PF11626.8 KXT06516.1 - 0.11 12.5 15.7 0.18 11.9 1.3 3.4 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF2789 PF10982.8 KXT06516.1 - 1.8 8.8 6.3 2.7 8.2 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2789) Sec2p PF06428.11 KXT06517.1 - 0.045 13.7 14.3 0.32 11.0 13.2 3.0 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p Spc29 PF17082.5 KXT06517.1 - 0.15 11.9 6.7 0.53 10.1 4.8 2.5 2 1 1 3 3 3 0 Spindle Pole Component 29 Baculo_PEP_C PF04513.12 KXT06517.1 - 0.18 11.8 4.4 3.8 7.6 0.1 2.7 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-RING_9 PF13901.6 KXT06517.1 - 0.33 10.9 4.3 0.32 10.9 2.0 2.0 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon DUF4795 PF16043.5 KXT06517.1 - 0.61 9.7 20.5 0.55 9.8 15.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) DUF4407 PF14362.6 KXT06517.1 - 1.3 8.4 12.6 2.5 7.4 12.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2408 PF10303.9 KXT06517.1 - 5.3 7.6 12.1 0.3 11.7 0.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) FapA PF03961.13 KXT06517.1 - 5.5 5.5 13.6 0.41 9.2 8.6 1.6 2 0 0 2 2 2 0 Flagellar Assembly Protein A DHO_dh PF01180.21 KXT06518.1 - 5.9e-23 81.5 0.0 8.2e-23 81.0 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.15 KXT06518.1 - 2.7 7.3 7.4 4.2 6.7 7.4 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase GCN5L1 PF06320.13 KXT06519.1 - 2.9e-19 69.3 5.0 3.4e-19 69.1 5.0 1.0 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) Bacillus_HBL PF05791.11 KXT06519.1 - 0.0073 16.2 0.3 0.009 15.9 0.3 1.2 1 0 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) LMBR1 PF04791.16 KXT06519.1 - 0.034 13.1 1.3 0.037 13.0 1.3 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein OmpH PF03938.14 KXT06519.1 - 0.047 14.0 6.0 0.065 13.6 6.0 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) ERp29_N PF07912.13 KXT06519.1 - 0.062 13.5 0.0 0.081 13.1 0.0 1.3 1 0 0 1 1 1 0 ERp29, N-terminal domain DUF4407 PF14362.6 KXT06519.1 - 0.11 11.8 4.1 0.12 11.7 4.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_13 PF13166.6 KXT06519.1 - 0.12 11.0 5.0 0.15 10.7 5.0 1.0 1 0 0 1 1 1 0 AAA domain ADIP PF11559.8 KXT06519.1 - 0.14 12.3 5.6 0.18 11.9 5.6 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding TMP_2 PF06791.13 KXT06519.1 - 0.27 10.9 8.0 0.35 10.5 8.0 1.1 1 0 0 1 1 1 0 Prophage tail length tape measure protein HAUS6_N PF14661.6 KXT06519.1 - 0.34 10.5 4.7 0.4 10.2 4.7 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus ABC_tran_Xtn PF12848.7 KXT06519.1 - 3.3 7.8 8.6 2.3 8.3 7.3 1.5 1 1 0 1 1 1 0 ABC transporter MatE PF01554.18 KXT06520.1 - 4.5e-64 214.9 19.3 1.5e-32 112.5 7.0 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KXT06520.1 - 2.3e-08 34.2 9.8 2.3e-08 34.2 9.8 3.9 4 1 0 4 4 4 2 Polysaccharide biosynthesis C-terminal domain MatE PF01554.18 KXT06521.1 - 4.5e-64 214.9 19.3 1.5e-32 112.5 7.0 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KXT06521.1 - 2.3e-08 34.2 9.8 2.3e-08 34.2 9.8 3.9 4 1 0 4 4 4 2 Polysaccharide biosynthesis C-terminal domain Arginase PF00491.21 KXT06522.1 - 1.9e-69 234.3 0.1 2.3e-69 234.0 0.1 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KXT06522.1 - 0.03 14.5 0.0 0.044 14.0 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain Zn_clus PF00172.18 KXT06523.1 - 2.8e-05 24.1 35.3 0.023 14.8 2.1 5.3 3 1 1 4 4 4 3 Fungal Zn(2)-Cys(6) binuclear cluster domain Tubulin PF00091.25 KXT06524.1 - 6.6e-69 232.1 0.0 3e-68 229.9 0.0 1.8 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KXT06524.1 - 8.6e-43 145.5 0.0 1.4e-42 144.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KXT06524.1 - 5.2e-05 23.5 0.0 0.00015 22.0 0.0 1.8 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KXT06524.1 - 0.0031 17.2 0.0 0.0057 16.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 KXT06524.1 - 0.0038 16.5 0.0 0.023 13.9 0.0 1.9 2 0 0 2 2 2 1 Tubulin like GMC_oxred_N PF00732.19 KXT06525.1 - 9.8e-28 97.4 0.0 8.4e-19 68.0 0.0 3.1 3 0 0 3 3 3 2 GMC oxidoreductase GMC_oxred_C PF05199.13 KXT06525.1 - 1e-26 94.2 0.0 1.7e-26 93.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KXT06525.1 - 2.1e-06 27.9 0.0 2.1e-06 27.9 0.0 2.3 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXT06525.1 - 0.00017 21.0 0.0 0.00028 20.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXT06525.1 - 0.001 18.3 0.1 0.002 17.3 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 KXT06525.1 - 0.0024 17.2 0.0 0.0039 16.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KXT06525.1 - 0.0051 15.9 0.2 0.015 14.4 0.1 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KXT06525.1 - 0.029 13.6 0.2 1.7 7.8 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXT06525.1 - 0.083 11.6 0.1 0.12 11.1 0.1 1.1 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 KXT06525.1 - 0.11 11.6 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 KXT06525.1 - 0.17 11.2 0.0 0.31 10.3 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase 4HBT PF03061.22 KXT06527.1 - 4.5e-08 33.3 0.0 8.2e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily Ribosomal_L29 PF00831.23 KXT06528.1 - 1.5e-18 66.5 1.4 1.5e-18 66.5 1.4 2.2 2 0 0 2 2 2 1 Ribosomal L29 protein Exonuc_VII_L PF02601.15 KXT06528.1 - 0.66 9.5 6.2 0.78 9.3 6.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit 2-oxoacid_dh PF00198.23 KXT06529.1 - 5.2e-76 255.1 0.9 7.8e-76 254.6 0.4 1.5 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KXT06529.1 - 5.3e-18 64.6 0.0 9.4e-18 63.8 0.0 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KXT06529.1 - 3.3e-14 52.9 0.0 8e-14 51.7 0.0 1.7 1 0 0 1 1 1 1 e3 binding domain Mating_N PF12731.7 KXT06529.1 - 0.045 13.8 0.2 0.091 12.9 0.2 1.5 1 0 0 1 1 1 0 Mating-type protein beta 1 AAA_33 PF13671.6 KXT06530.1 - 7.1e-11 42.4 0.0 9e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain SKI PF01202.22 KXT06530.1 - 2.9e-10 40.5 0.0 3.8e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 KXT06530.1 - 1.4e-07 32.1 0.0 3.4e-07 30.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KXT06530.1 - 4.4e-05 23.9 0.0 9.8e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KXT06530.1 - 0.00058 20.1 0.1 0.0015 18.8 0.0 1.7 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KXT06530.1 - 0.002 18.6 0.0 0.0022 18.4 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain Cytidylate_kin PF02224.18 KXT06530.1 - 0.0036 17.1 0.1 0.014 15.1 0.0 1.9 1 1 1 2 2 2 1 Cytidylate kinase Rad17 PF03215.15 KXT06530.1 - 0.0037 17.2 0.0 0.0069 16.3 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_28 PF13521.6 KXT06530.1 - 0.0048 17.2 0.1 0.016 15.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KXT06530.1 - 0.0053 16.7 0.0 0.029 14.3 0.0 1.9 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA PF00004.29 KXT06530.1 - 0.0068 16.8 0.1 0.014 15.8 0.1 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KXT06530.1 - 0.0069 16.1 0.0 0.058 13.1 0.0 2.1 2 0 0 2 2 2 1 Sigma-54 interaction domain dNK PF01712.19 KXT06530.1 - 0.007 16.2 0.0 0.9 9.4 0.0 2.1 2 0 0 2 2 2 1 Deoxynucleoside kinase PRK PF00485.18 KXT06530.1 - 0.019 14.7 0.0 0.041 13.6 0.0 1.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Sigma54_activ_2 PF14532.6 KXT06530.1 - 0.019 15.1 0.0 0.036 14.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 KXT06530.1 - 0.031 14.8 0.0 0.041 14.4 0.0 1.5 1 1 0 1 1 1 0 ABC transporter APS_kinase PF01583.20 KXT06530.1 - 0.034 14.0 0.0 0.049 13.5 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_30 PF13604.6 KXT06530.1 - 0.042 13.6 0.3 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KXT06530.1 - 0.044 14.3 0.0 0.077 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KXT06530.1 - 0.068 12.5 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 KXT06530.1 - 0.087 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 KXT06530.1 - 0.09 12.3 0.0 0.23 10.9 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region PhoH PF02562.16 KXT06530.1 - 0.14 11.6 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.22 KXT06530.1 - 0.18 12.2 0.0 0.6 10.5 0.0 1.8 2 0 0 2 2 2 0 RNA helicase Vps26 PF03643.15 KXT06531.1 - 9.8e-124 411.8 0.1 1.2e-123 411.6 0.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 KXT06531.1 - 0.0023 18.0 0.2 0.51 10.4 0.0 3.0 2 1 1 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Adaptin_N PF01602.20 KXT06533.1 - 8.8e-95 318.2 10.0 1.3e-94 317.6 10.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 KXT06533.1 - 2.5e-57 192.7 0.7 6.2e-57 191.4 0.7 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 KXT06533.1 - 1.6e-55 186.5 0.0 4.9e-55 185.0 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 KXT06533.1 - 4.5e-15 56.1 5.4 2.8e-11 43.7 0.0 3.1 1 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KXT06533.1 - 8.5e-10 38.9 5.5 0.002 18.5 0.0 5.0 3 2 2 5 5 5 4 HEAT repeats Coatomer_g_Cpla PF16381.5 KXT06533.1 - 2.8e-06 27.5 0.2 0.00041 20.5 0.0 3.1 3 0 0 3 3 3 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT PF02985.22 KXT06533.1 - 0.00012 22.0 1.8 1.4 9.4 0.0 4.8 5 0 0 5 5 5 1 HEAT repeat HTH_44 PF14641.6 KXT06533.1 - 0.043 14.2 0.2 0.12 12.8 0.2 1.7 1 0 0 1 1 1 0 Helix-turn-helix DNA-binding domain of SPT6 HEAT_EZ PF13513.6 KXT06533.1 - 0.14 12.7 1.5 4.5 7.9 0.0 3.9 4 0 0 4 4 4 0 HEAT-like repeat bZIP_2 PF07716.15 KXT06534.1 - 1.2e-07 31.7 1.0 1.9e-07 31.0 1.0 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KXT06534.1 - 3e-05 24.0 0.2 4.6e-05 23.4 0.2 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KXT06534.1 - 0.022 15.2 0.8 0.037 14.5 0.8 1.2 1 0 0 1 1 1 0 bZIP Maf transcription factor Aldedh PF00171.22 KXT06535.1 - 1.7e-102 343.4 0.0 2.1e-102 343.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HicA_toxin PF07927.12 KXT06536.1 - 0.00043 20.3 0.0 0.00081 19.4 0.0 1.5 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, Mob1_phocein PF03637.17 KXT06537.1 - 2.2e-38 132.0 0.1 4.1e-38 131.1 0.1 1.4 1 0 0 1 1 1 1 Mob1/phocein family UQ_con PF00179.26 KXT06538.1 - 5.5e-19 68.2 0.0 5.7e-19 68.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KXT06538.1 - 0.0013 19.0 0.0 0.0014 18.9 0.0 1.2 1 0 0 1 1 1 1 RWD domain Exo_endo_phos PF03372.23 KXT06566.1 - 1.8e-08 34.2 0.0 3.8e-08 33.1 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Zn_clus PF00172.18 KXT06567.1 - 3.3e-08 33.5 11.3 5.1e-08 32.9 11.3 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXT06567.1 - 9.9e-06 24.6 4.5 1.2e-05 24.4 1.2 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT06568.1 - 3.4e-08 33.5 11.3 5.2e-08 32.9 11.3 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXT06568.1 - 8.5e-06 24.8 4.2 1.1e-05 24.5 1.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT06569.1 - 3.3e-08 33.5 11.3 5.1e-08 32.9 11.3 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXT06569.1 - 9.9e-06 24.6 4.5 1.2e-05 24.4 1.2 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT06570.1 - 3.3e-08 33.5 11.3 5.1e-08 32.9 11.3 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXT06570.1 - 9.9e-06 24.6 4.5 1.2e-05 24.4 1.2 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain IRF PF00605.17 KXT06571.1 - 0.034 14.4 0.7 0.24 11.7 0.7 2.3 2 1 0 2 2 2 0 Interferon regulatory factor transcription factor IRF PF00605.17 KXT06572.1 - 0.11 12.8 0.8 0.59 10.4 0.4 2.3 2 1 1 3 3 3 0 Interferon regulatory factor transcription factor Citrate_synt PF00285.21 KXT06573.1 - 2.5e-101 339.3 0.0 3.3e-101 339.0 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Eclosion PF04736.12 KXT06573.1 - 0.24 11.1 0.0 0.42 10.3 0.0 1.3 1 0 0 1 1 1 0 Eclosion hormone Peptidase_S9 PF00326.21 KXT06574.1 - 3e-06 26.9 0.0 5.6e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KXT06574.1 - 0.0049 16.5 0.2 0.0098 15.6 0.2 1.5 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 KXT06574.1 - 0.0056 16.5 0.0 0.02 14.7 0.0 1.8 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase Fungal_trans PF04082.18 KXT06575.1 - 1.5e-19 70.0 0.0 2.9e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT06575.1 - 1e-07 31.9 12.9 2.1e-07 30.9 12.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spc24 PF08286.11 KXT06575.1 - 0.13 12.5 0.7 0.3 11.3 0.7 1.6 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Mito_carr PF00153.27 KXT06576.1 - 3.4e-28 97.4 7.1 1.8e-13 50.2 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.25 KXT06577.1 - 3.6e-45 154.4 0.0 1.2e-44 152.6 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT06577.1 - 1.3e-13 50.9 0.0 4.1e-13 49.2 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXT06578.1 - 3.6e-45 154.4 0.0 1.2e-44 152.6 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT06578.1 - 1.3e-13 50.9 0.0 4.1e-13 49.2 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pan3_PK PF18101.1 KXT06579.1 - 5.9e-54 181.8 0.1 4.2e-53 179.0 0.1 2.1 1 1 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 KXT06579.1 - 0.055 12.8 0.0 0.093 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Pkinase_Tyr PF07714.17 KXT06579.1 - 0.12 11.7 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 KXT06580.1 - 3.6e-45 154.4 0.0 1.2e-44 152.6 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT06580.1 - 1.3e-13 50.9 0.0 4.1e-13 49.2 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pan3_PK PF18101.1 KXT06581.1 - 3.4e-54 182.6 0.1 2.9e-53 179.6 0.1 2.1 1 1 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 KXT06581.1 - 0.039 13.3 0.0 0.064 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Pkinase_Tyr PF07714.17 KXT06581.1 - 0.084 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 KXT06582.1 - 3.6e-45 154.4 0.0 1.2e-44 152.6 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT06582.1 - 1.3e-13 50.9 0.0 4.1e-13 49.2 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXT06583.1 - 3.6e-45 154.4 0.0 1.2e-44 152.6 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT06583.1 - 1.3e-13 50.9 0.0 4.1e-13 49.2 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KXT06584.1 - 3.6e-45 154.4 0.0 1.2e-44 152.6 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT06584.1 - 1.3e-13 50.9 0.0 4.1e-13 49.2 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Cupin_2 PF07883.11 KXT06586.1 - 2.5e-15 55.9 0.9 3.9e-10 39.3 0.1 2.7 3 0 0 3 3 3 2 Cupin domain AraC_binding PF02311.19 KXT06586.1 - 3e-08 33.7 0.8 0.0021 17.9 0.1 2.2 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_3 PF05899.12 KXT06586.1 - 6.2e-06 25.8 0.0 0.041 13.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_1 PF00190.22 KXT06586.1 - 0.0039 16.8 0.3 0.075 12.6 0.0 2.5 2 1 0 2 2 2 1 Cupin FdtA PF05523.11 KXT06586.1 - 0.01 15.6 0.0 0.028 14.1 0.0 1.7 2 0 0 2 2 2 0 WxcM-like, C-terminal MannoseP_isomer PF01050.18 KXT06586.1 - 0.11 12.3 0.0 3.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Mannose-6-phosphate isomerase WD40 PF00400.32 KXT06587.1 - 1.8e-16 60.2 10.1 5.9e-05 23.8 0.1 5.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXT06587.1 - 1.9e-06 28.1 0.0 0.024 14.9 0.0 3.8 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KXT06587.1 - 0.013 14.8 0.0 0.17 11.2 0.0 2.1 2 0 0 2 2 2 0 WD40-like domain Ge1_WD40 PF16529.5 KXT06587.1 - 0.15 11.0 0.3 4.4 6.2 0.1 2.6 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cyt-b5 PF00173.28 KXT06588.1 - 4.6e-19 68.3 1.7 6.3e-19 67.9 0.1 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 KXT06588.1 - 8.8e-12 45.5 18.4 8.8e-12 45.5 18.4 1.6 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.13 KXT06588.1 - 0.012 15.8 0.2 0.029 14.6 0.2 1.5 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region COX14 PF14880.6 KXT06588.1 - 0.041 13.7 1.3 0.11 12.4 0.2 2.2 2 0 0 2 2 2 0 Cytochrome oxidase c assembly RNR_inhib PF08591.10 KXT06589.1 - 3.2e-11 44.5 4.0 3.2e-11 44.5 4.0 2.9 2 1 1 3 3 3 1 Ribonucleotide reductase inhibitor Nucleo_P87 PF07267.11 KXT06589.1 - 0.0057 15.6 1.6 0.0066 15.4 1.6 1.1 1 0 0 1 1 1 1 Nucleopolyhedrovirus capsid protein P87 PBP1_TM PF14812.6 KXT06589.1 - 0.1 13.0 1.3 0.19 12.1 1.3 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Acyl-CoA_dh_2 PF08028.11 KXT06590.1 - 0.36 11.1 7.1 0.092 13.0 2.9 1.9 1 1 1 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain S1 PF00575.23 KXT06591.1 - 8.9e-67 221.4 28.3 8.5e-15 54.9 0.3 13.5 14 0 0 14 14 14 10 S1 RNA binding domain TPR_14 PF13428.6 KXT06591.1 - 9.4e-07 29.2 0.9 3.8 8.6 0.0 5.1 3 1 2 5 5 5 2 Tetratricopeptide repeat Suf PF05843.14 KXT06591.1 - 0.00013 22.1 18.8 0.11 12.5 0.1 4.7 4 1 1 5 5 5 3 Suppressor of forked protein (Suf) RNase_II_C_S1 PF18614.1 KXT06591.1 - 0.00024 21.0 17.2 1.4 8.9 0.0 8.3 9 0 0 9 9 9 1 RNase II-type exonuclease C-terminal S1 domain TPR_8 PF13181.6 KXT06591.1 - 0.04 14.1 0.0 0.61 10.4 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat NRDE-2 PF08424.10 KXT06591.1 - 0.084 12.0 6.9 0.36 9.9 0.2 3.1 1 1 0 2 2 2 0 NRDE-2, necessary for RNA interference RPN7 PF10602.9 KXT06591.1 - 0.11 12.2 0.2 0.68 9.6 0.1 2.2 1 1 1 2 2 2 0 26S proteasome subunit RPN7 TPR_17 PF13431.6 KXT06591.1 - 0.24 11.9 0.8 1.9 9.1 0.2 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat PCB_OB PF17092.5 KXT06591.1 - 0.33 11.7 17.0 7.1 7.4 0.2 7.4 7 1 1 8 8 8 0 Penicillin-binding protein OB-like domain TPR_19 PF14559.6 KXT06591.1 - 0.36 11.4 9.8 3.7 8.1 0.1 4.1 4 1 1 5 5 5 0 Tetratricopeptide repeat Abhydrolase_3 PF07859.13 KXT06592.1 - 8.8e-08 32.3 0.0 1.2e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KXT06592.1 - 7.4e-07 28.4 0.1 1.9e-06 27.1 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family Methyltransf_23 PF13489.6 KXT06593.1 - 2e-13 50.5 0.0 3e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXT06593.1 - 2.5e-10 40.9 0.0 4.1e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXT06593.1 - 4.1e-10 40.2 0.0 6.2e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXT06593.1 - 1e-07 31.9 0.0 1.3e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXT06593.1 - 2.1e-07 31.6 0.0 3.8e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXT06593.1 - 7.4e-06 25.5 0.0 1e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PHD PF00628.29 KXT06595.1 - 3.5e-05 23.6 9.4 6.3e-05 22.8 9.4 1.4 1 0 0 1 1 1 1 PHD-finger PHD_3 PF13922.6 KXT06595.1 - 0.00017 21.9 1.5 0.00083 19.7 1.5 2.3 1 0 0 1 1 1 1 PHD domain of transcriptional enhancer, Asx Presenilin PF01080.17 KXT06595.1 - 1.4 7.6 4.5 2.5 6.8 4.5 1.3 1 0 0 1 1 1 0 Presenilin PHD PF00628.29 KXT06596.1 - 3.5e-05 23.6 9.4 6.3e-05 22.8 9.4 1.4 1 0 0 1 1 1 1 PHD-finger PHD_3 PF13922.6 KXT06596.1 - 0.00017 21.9 1.5 0.00083 19.7 1.5 2.3 1 0 0 1 1 1 1 PHD domain of transcriptional enhancer, Asx Presenilin PF01080.17 KXT06596.1 - 1.4 7.6 4.5 2.5 6.8 4.5 1.3 1 0 0 1 1 1 0 Presenilin Bacillus_HBL PF05791.11 KXT06598.1 - 0.001 18.9 1.6 0.001 18.9 1.6 1.9 2 0 0 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) Spc7 PF08317.11 KXT06598.1 - 0.0036 16.2 6.5 0.0036 16.2 6.5 2.4 2 0 0 2 2 2 1 Spc7 kinetochore protein HMMR_N PF15905.5 KXT06598.1 - 0.034 13.6 19.5 0.32 10.4 5.3 3.1 2 1 1 3 3 3 0 Hyaluronan mediated motility receptor N-terminal DUF4407 PF14362.6 KXT06598.1 - 0.13 11.6 17.1 0.11 11.8 8.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) SNARE PF05739.19 KXT06598.1 - 0.13 12.2 0.4 0.42 10.7 0.4 1.9 1 0 0 1 1 1 0 SNARE domain FYVE PF01363.21 KXT06599.1 - 5.6e-22 77.7 22.1 2.5e-16 59.5 5.8 3.0 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.8 KXT06599.1 - 6.5e-18 64.2 1.8 1.5e-17 63.0 1.8 1.7 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-AN1 PF01428.16 KXT06599.1 - 7.5e-05 22.8 2.4 7.5e-05 22.8 2.4 4.0 4 1 1 5 5 5 1 AN1-like Zinc finger Seryl_tRNA_N PF02403.22 KXT06599.1 - 0.027 14.7 2.9 0.073 13.3 2.9 1.7 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Anillin_N PF16018.5 KXT06599.1 - 0.099 13.3 0.7 1.3 9.6 0.1 2.8 2 0 0 2 2 2 0 Anillin N-terminus TMF_TATA_bd PF12325.8 KXT06599.1 - 0.1 12.9 3.4 0.25 11.6 3.4 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding zf-met PF12874.7 KXT06599.1 - 1.2 9.7 9.8 3.2 8.3 0.2 4.4 4 0 0 4 4 4 0 Zinc-finger of C2H2 type UBZ_FAAP20 PF15750.5 KXT06599.1 - 1.6 8.7 7.7 16 5.5 1.0 3.8 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger zf-Di19 PF05605.12 KXT06599.1 - 1.7 9.0 14.6 3.6 8.0 0.0 3.6 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-ribbon_3 PF13248.6 KXT06599.1 - 2 7.9 18.8 0.046 13.2 0.7 4.8 5 0 0 5 5 5 0 zinc-ribbon domain ABC_tran_CTD PF16326.5 KXT06599.1 - 3.7 7.9 7.0 12 6.2 0.1 3.3 3 1 1 4 4 4 0 ABC transporter C-terminal domain zinc_ribbon_15 PF17032.5 KXT06599.1 - 6.4 7.6 15.0 55 4.6 1.2 4.3 4 1 0 4 4 4 0 zinc-ribbon family Solute_trans_a PF03619.16 KXT06601.1 - 2.5e-95 319.0 12.7 3.1e-95 318.7 12.7 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF5521 PF17659.1 KXT06601.1 - 0.66 7.8 5.1 1 7.1 5.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5521) MMS1_N PF10433.9 KXT06603.1 - 3.5e-71 240.3 0.0 7.1e-71 239.3 0.0 1.5 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term DUF4596 PF15363.6 KXT06604.1 - 0.13 12.5 1.1 8.5 6.7 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4596) TauD PF02668.16 KXT06605.1 - 1.1e-31 110.7 0.5 2.3e-31 109.6 0.3 1.6 1 1 1 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KXT06605.1 - 0.025 13.7 0.0 0.044 12.9 0.0 1.3 1 0 0 1 1 1 0 CsiD DUF5401 PF17380.2 KXT06605.1 - 0.11 10.5 0.1 0.15 10.1 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) RRP36 PF06102.12 KXT06605.1 - 0.11 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 AA_permease_2 PF13520.6 KXT06606.1 - 9e-68 229.0 36.7 1.2e-67 228.7 36.7 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXT06606.1 - 1.9e-13 49.8 20.3 1.9e-13 49.8 20.3 2.0 2 0 0 2 2 2 1 Amino acid permease PI3_PI4_kinase PF00454.27 KXT06607.1 - 5e-40 137.9 0.0 8.2e-40 137.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase NDUF_B4 PF07225.12 KXT06608.1 - 0.0049 16.8 0.1 0.0054 16.6 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) DAO PF01266.24 KXT06609.1 - 1.8e-30 106.7 0.1 2.3e-30 106.4 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXT06609.1 - 2.9e-06 27.4 0.0 0.031 14.3 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KXT06609.1 - 9.3e-05 22.6 0.0 0.00038 20.6 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXT06609.1 - 0.00012 21.4 0.1 0.0025 17.1 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KXT06609.1 - 0.0068 15.3 0.0 2.3 7.0 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase GIDA PF01134.22 KXT06609.1 - 0.0079 15.3 0.0 0.05 12.7 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Sacchrp_dh_NADP PF03435.18 KXT06609.1 - 0.015 15.5 0.0 0.27 11.5 0.0 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Thi4 PF01946.17 KXT06609.1 - 0.026 13.8 0.0 0.048 12.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 KXT06609.1 - 0.053 12.6 0.0 6.2 5.8 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein TrkA_N PF02254.18 KXT06609.1 - 0.054 13.8 0.0 0.093 13.0 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.20 KXT06609.1 - 0.13 12.4 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.6 KXT06609.1 - 0.13 11.4 0.0 2.1 7.5 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ketoacyl-synt PF00109.26 KXT06610.1 - 1.5e-74 250.8 0.0 2.9e-74 249.8 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 KXT06610.1 - 2.2e-54 184.7 0.0 4.1e-54 183.8 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 KXT06610.1 - 1e-53 181.9 0.2 5.2e-53 179.6 0.0 2.5 3 0 0 3 3 1 1 KR domain Acyl_transf_1 PF00698.21 KXT06610.1 - 1.3e-45 156.3 0.0 2.3e-45 155.5 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXT06610.1 - 1.2e-36 125.3 0.2 3.2e-36 123.9 0.2 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KXT06610.1 - 6.2e-21 75.0 0.0 2e-20 73.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 KXT06610.1 - 2.5e-20 73.9 0.0 2.3e-19 70.8 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KXT06610.1 - 1.5e-17 63.8 0.0 9.2e-17 61.2 0.0 2.5 2 0 0 2 2 1 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 KXT06610.1 - 1.4e-13 51.3 0.0 4.5e-13 49.6 0.0 1.9 2 0 0 2 2 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 KXT06610.1 - 1.4e-13 51.3 0.0 6.3e-13 49.2 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXT06610.1 - 4.1e-13 49.8 0.0 6e-12 46.1 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXT06610.1 - 1.5e-11 44.4 0.0 3.2e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXT06610.1 - 4.4e-11 42.8 0.0 1.4e-10 41.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KXT06610.1 - 4.6e-09 36.0 0.1 9.3e-08 31.8 0.0 2.8 3 0 0 3 3 3 1 short chain dehydrogenase Thiolase_N PF00108.23 KXT06610.1 - 4.8e-07 29.4 0.1 1e-06 28.3 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.25 KXT06610.1 - 5.6e-07 29.8 0.0 1.5e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 KXT06610.1 - 0.00012 21.9 0.0 0.00035 20.4 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ubie_methyltran PF01209.18 KXT06610.1 - 0.00028 20.3 0.0 0.00069 19.0 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.6 KXT06610.1 - 0.00055 20.9 0.0 0.0023 18.9 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_33 PF10017.9 KXT06610.1 - 0.0017 17.5 0.0 0.0053 16.0 0.0 1.7 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_16 PF10294.9 KXT06610.1 - 0.0071 16.1 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_28 PF02636.17 KXT06610.1 - 0.028 14.0 0.0 0.065 12.8 0.0 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DREV PF05219.12 KXT06610.1 - 0.033 13.3 0.0 0.077 12.1 0.0 1.5 1 0 0 1 1 1 0 DREV methyltransferase Viral_Rep PF02407.16 KXT06610.1 - 0.046 14.0 0.0 12 6.2 0.0 3.4 3 0 0 3 3 3 0 Putative viral replication protein SAT PF16073.5 KXT06610.1 - 0.051 13.3 0.4 0.19 11.4 0.4 1.9 1 1 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis NodS PF05401.11 KXT06610.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 Nodulation protein S (NodS) ACP_syn_III PF08545.10 KXT06610.1 - 0.19 11.6 1.2 0.42 10.5 0.3 2.1 2 0 0 2 2 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ApbA_C PF08546.11 KXT06611.1 - 2.2e-27 95.7 0.0 4.1e-27 94.8 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KXT06611.1 - 7.1e-27 93.9 0.0 9.7e-27 93.5 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DAO PF01266.24 KXT06611.1 - 0.0086 15.7 0.9 0.097 12.2 1.2 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase ELFV_dehydrog PF00208.21 KXT06611.1 - 0.036 13.8 0.0 0.054 13.2 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Sacchrp_dh_NADP PF03435.18 KXT06611.1 - 0.094 13.0 0.4 0.19 12.0 0.2 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 KXT06611.1 - 0.11 13.0 0.0 0.22 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 KXT06611.1 - 0.14 12.2 0.4 0.38 10.8 0.1 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 KXT06611.1 - 0.15 11.3 0.2 0.2 10.8 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 KXT06611.1 - 0.16 12.5 0.5 0.32 11.6 0.5 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DEAD PF00270.29 KXT06612.1 - 4.5e-47 160.1 0.0 8.2e-47 159.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXT06612.1 - 5.2e-29 100.8 0.6 2.5e-28 98.6 0.3 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain UTP25 PF06862.12 KXT06612.1 - 1.1e-05 24.5 3.3 5.2e-05 22.2 0.4 2.8 2 1 1 3 3 3 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 SNAD2 PF18745.1 KXT06612.1 - 0.11 12.2 1.2 0.22 11.2 1.2 1.5 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 2 Aldo_ket_red PF00248.21 KXT06613.1 - 4.7e-40 137.6 0.1 1.8e-38 132.4 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family ColG_sub PF18496.1 KXT06613.1 - 0.036 14.2 0.0 0.079 13.1 0.0 1.5 1 0 0 1 1 1 0 Collagenase G catalytic helper subdomain DUF2635 PF10948.8 KXT06613.1 - 0.19 11.4 0.2 0.86 9.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2635) CTD_bind PF04818.13 KXT06614.1 - 4.8e-06 27.3 0.0 1.3e-05 26.0 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_1 PF00076.22 KXT06614.1 - 7.3e-06 25.7 0.1 1.4e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA PF03153.13 KXT06614.1 - 1.6 8.6 14.8 3 7.7 14.8 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ANAPC10 PF03256.16 KXT06615.1 - 2.1e-44 151.4 0.0 3.8e-44 150.5 0.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) BCNT PF07572.12 KXT06615.1 - 2.7e-14 53.0 2.9 4.8e-14 52.2 0.8 2.4 2 0 0 2 2 2 1 Bucentaur or craniofacial development Nucleo_P87 PF07267.11 KXT06615.1 - 2.4 6.9 12.7 1.5 7.6 10.4 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 FA_desaturase PF00487.24 KXT06616.1 - 2.9e-24 86.3 19.3 8.1e-24 84.8 19.3 1.6 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KXT06616.1 - 1e-05 25.7 0.0 2.2e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) UPF0061 PF02696.14 KXT06617.1 - 2.7e-129 432.0 0.0 3.4e-129 431.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Amidase PF01425.21 KXT06618.1 - 1.8e-94 317.2 0.0 2.2e-94 317.0 0.0 1.1 1 0 0 1 1 1 1 Amidase Meth_synt_2 PF01717.18 KXT06619.1 - 2.5e-19 69.7 0.0 6.4e-12 45.4 0.0 2.1 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KXT06619.1 - 4e-05 23.3 0.0 0.01 15.4 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain adh_short PF00106.25 KXT06622.1 - 1.6e-39 135.4 1.4 2.6e-39 134.7 1.4 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT06622.1 - 1.5e-37 129.4 1.7 2.3e-36 125.5 1.7 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT06622.1 - 5.8e-08 32.9 4.3 8.6e-08 32.3 0.2 2.2 2 0 0 2 2 2 1 KR domain DUF1776 PF08643.10 KXT06622.1 - 0.063 12.6 0.0 0.081 12.3 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) ADH_zinc_N PF00107.26 KXT06622.1 - 0.066 13.2 0.5 0.32 11.0 0.5 2.0 1 1 0 1 1 1 0 Zinc-binding dehydrogenase AA_permease_2 PF13520.6 KXT06623.1 - 1.7e-49 168.8 44.7 2e-49 168.6 44.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXT06623.1 - 1.5e-21 76.5 37.3 2.1e-21 76.1 37.3 1.1 1 0 0 1 1 1 1 Amino acid permease IBR PF01485.21 KXT06624.1 - 1.5e-19 70.0 34.7 1.4e-14 54.1 2.5 4.2 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain RWD PF05773.22 KXT06624.1 - 1.1e-14 54.7 0.0 2.1e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 RWD domain zf-RING_UBOX PF13445.6 KXT06624.1 - 3.3e-05 23.8 5.6 3.3e-05 23.8 5.6 3.6 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 KXT06624.1 - 0.00068 19.9 7.8 0.00068 19.9 7.8 3.7 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4 PF00097.25 KXT06624.1 - 0.00072 19.4 6.8 0.00072 19.4 6.8 4.3 4 1 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) Flagellin_IN PF07196.13 KXT06625.1 - 8.9 6.6 9.1 0.4 10.9 1.6 2.7 3 0 0 3 3 3 0 Flagellin hook IN motif Lipase_2 PF01674.18 KXT06626.1 - 0.00031 20.3 0.0 0.0024 17.4 0.0 2.1 1 1 0 1 1 1 1 Lipase (class 2) Lipase_2 PF01674.18 KXT06627.1 - 0.00031 20.3 0.0 0.0024 17.4 0.0 2.1 1 1 0 1 1 1 1 Lipase (class 2) vWA-TerF-like PF10138.9 KXT06629.1 - 3.8e-09 36.9 0.1 5.4e-09 36.5 0.1 1.1 1 0 0 1 1 1 1 vWA found in TerF C terminus Pro_racemase PF05544.11 KXT06629.1 - 0.17 10.9 0.0 0.23 10.5 0.0 1.1 1 0 0 1 1 1 0 Proline racemase Pro-rich PF15240.6 KXT06629.1 - 0.89 9.8 80.7 0.64 10.3 32.9 2.4 2 0 0 2 2 2 0 Proline-rich vWA-TerF-like PF10138.9 KXT06630.1 - 6.2e-09 36.3 0.1 8.9e-09 35.7 0.1 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus SNF2_N PF00176.23 KXT06631.1 - 1.2e-64 218.3 0.0 1e-63 215.2 0.0 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXT06631.1 - 1.7e-21 76.6 0.1 8.6e-20 71.1 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXT06631.1 - 1.1e-06 28.8 0.2 6.2e-06 26.3 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KXT06631.1 - 2.5e-05 23.6 0.3 0.0039 16.4 0.0 3.0 3 0 0 3 3 3 2 Class II histone deacetylase complex subunits 2 and 3 DUF1003 PF06210.11 KXT06631.1 - 0.49 10.5 2.3 1.5 9.0 2.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) Chorismate_bind PF00425.18 KXT06633.1 - 2.4e-81 273.1 0.0 3.3e-81 272.7 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 KXT06633.1 - 1.8e-28 99.6 0.0 3.6e-28 98.6 0.0 1.5 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 KXT06633.1 - 4.1e-16 59.5 0.0 7.8e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 KXT06633.1 - 2e-05 24.4 1.1 0.00014 21.7 1.1 2.1 1 1 0 1 1 1 1 Peptidase C26 PseudoU_synth_2 PF00849.22 KXT06634.1 - 3.8e-30 105.1 0.0 5.7e-30 104.5 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 KXT06634.1 - 5.9e-05 22.7 0.3 0.00083 19.0 0.1 2.4 2 0 0 2 2 2 1 S4 domain Auto_anti-p27 PF06677.12 KXT06634.1 - 0.064 13.4 0.1 0.15 12.2 0.1 1.5 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) SLAC1 PF03595.17 KXT06635.1 - 3.5e-89 299.3 48.7 4e-89 299.1 48.7 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel COPI_assoc PF08507.10 KXT06635.1 - 4.4 7.4 14.8 0.027 14.5 3.3 2.4 2 1 0 2 2 2 0 COPI associated protein Sld7_C PF18596.1 KXT06636.1 - 9.2e-29 99.4 0.1 1.7e-28 98.5 0.1 1.5 1 0 0 1 1 1 1 Sld7 C-terminal domain Gene66 PF02053.15 KXT06636.1 - 0.011 15.4 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 Gene 66 (IR5) protein Glyco_hydro_42 PF02449.15 KXT06639.1 - 4.2e-112 375.2 4.7 5.6e-112 374.8 4.7 1.1 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_42M PF08532.10 KXT06639.1 - 5.2e-22 78.4 0.0 8.4e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase trimerisation domain Cellulase PF00150.18 KXT06639.1 - 9e-07 28.6 0.9 0.00044 19.8 0.5 2.3 1 1 1 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_14 PF01373.17 KXT06639.1 - 0.0038 16.2 0.1 0.0068 15.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 14 Glyco_hydro_35 PF01301.19 KXT06639.1 - 0.017 14.7 1.1 0.36 10.4 1.1 2.2 1 1 0 1 1 1 0 Glycosyl hydrolases family 35 DUF4434 PF14488.6 KXT06639.1 - 0.093 12.7 0.5 0.65 10.0 0.5 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4434) Apc15p PF05841.11 KXT06640.1 - 5.6e-15 56.2 3.8 5.6e-15 56.2 3.8 2.2 2 1 0 2 2 2 1 Apc15p protein BUD22 PF09073.10 KXT06640.1 - 0.02 14.2 14.5 0.03 13.7 14.5 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 KXT06640.1 - 0.14 10.3 18.4 0.22 9.7 18.4 1.2 1 0 0 1 1 1 0 Nop14-like family Elong_Iki1 PF10483.9 KXT06641.1 - 9.7e-101 337.2 0.0 1.8e-100 336.3 0.0 1.4 1 1 0 1 1 1 1 Elongator subunit Iki1 Med24_N PF11277.8 KXT06641.1 - 0.089 10.8 0.0 0.12 10.4 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal MFS_1 PF07690.16 KXT06642.1 - 6.4e-31 107.5 24.8 8.1e-31 107.2 24.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KXT06642.1 - 0.00076 18.9 5.5 0.036 13.4 4.1 2.3 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB PalH PF08733.10 KXT06642.1 - 2.5 7.0 9.3 0.41 9.6 2.9 2.1 2 0 0 2 2 2 0 PalH/RIM21 HisKA_7TM PF16927.5 KXT06642.1 - 4 7.4 18.2 0.65 10.0 4.2 3.1 3 1 1 4 4 4 0 N-terminal 7TM region of histidine kinase HSP70 PF00012.20 KXT06643.1 - 1e-162 542.4 6.7 1e-162 542.4 6.7 2.9 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 KXT06643.1 - 2.1e-12 46.6 0.0 1.3e-11 43.9 0.0 1.9 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 KXT06643.1 - 0.048 14.1 0.0 0.048 14.1 0.0 3.5 4 1 0 4 4 4 0 Cell division protein FtsA Fungal_trans PF04082.18 KXT06644.1 - 3.3e-10 39.4 0.0 6.2e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ldl_recept_b PF00058.17 KXT06645.1 - 0.0011 19.3 2.0 37 4.9 0.0 5.3 6 0 0 6 6 6 0 Low-density lipoprotein receptor repeat class B SGL PF08450.12 KXT06645.1 - 0.0014 18.2 0.8 0.015 14.9 0.3 2.7 1 1 1 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region DUF5050 PF16472.5 KXT06645.1 - 0.0079 15.5 0.0 0.1 11.8 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF5050) Neisseria_PilC PF05567.11 KXT06645.1 - 0.053 12.5 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Neisseria PilC beta-propeller domain NHL PF01436.21 KXT06645.1 - 0.22 11.6 0.9 59 4.0 0.0 4.4 5 0 0 5 5 5 0 NHL repeat Pentapeptide_4 PF13599.6 KXT06646.1 - 6.1e-13 48.7 3.0 1.8e-12 47.2 2.4 2.0 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 KXT06646.1 - 1.5e-09 37.3 4.5 1.5e-06 27.7 0.1 2.9 1 1 2 3 3 3 2 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.6 KXT06646.1 - 1.3e-07 31.6 6.2 6.6e-06 26.2 5.8 3.1 1 1 1 2 2 2 1 Pentapeptide repeats (9 copies) DinB_2 PF12867.7 KXT06646.1 - 0.052 14.1 0.9 0.19 12.2 0.2 2.3 3 0 0 3 3 3 0 DinB superfamily Beta_helix PF13229.6 KXT06646.1 - 0.22 11.3 0.0 0.43 10.4 0.0 1.4 1 0 0 1 1 1 0 Right handed beta helix region ASXH PF13919.6 KXT06647.1 - 1.2e-21 77.2 3.5 1.6e-21 76.8 3.5 1.2 1 0 0 1 1 1 1 Asx homology domain BTB PF00651.31 KXT06648.1 - 2e-08 34.4 0.0 3.4e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain HxlR PF01638.17 KXT06649.1 - 0.084 12.7 0.0 0.2 11.5 0.0 1.6 1 1 0 1 1 1 0 HxlR-like helix-turn-helix Cupin_1 PF00190.22 KXT06650.1 - 0.14 11.7 0.3 2.9 7.5 0.1 2.3 2 0 0 2 2 2 0 Cupin Choline_kinase PF01633.20 KXT06652.1 - 1.1e-59 201.6 0.0 4.9e-59 199.5 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase Choline_kin_N PF04428.14 KXT06652.1 - 2e-17 62.6 0.1 9e-17 60.5 0.0 2.2 2 0 0 2 2 2 1 Choline kinase N terminus APH PF01636.23 KXT06652.1 - 3.6e-05 23.8 0.3 0.00012 22.0 0.3 2.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family PGA2 PF07543.12 KXT06652.1 - 0.41 10.6 10.0 0.024 14.6 4.2 1.9 2 0 0 2 2 2 0 Protein trafficking PGA2 Heme_oxygenase PF01126.20 KXT06654.1 - 4.4e-09 36.4 0.0 5.6e-08 32.8 0.0 2.0 2 0 0 2 2 2 1 Heme oxygenase LGT PF01790.18 KXT06656.1 - 0.0063 15.8 0.0 0.0067 15.7 0.0 1.1 1 0 0 1 1 1 1 Prolipoprotein diacylglyceryl transferase DUF3302 PF11742.8 KXT06656.1 - 0.04 14.0 0.1 0.062 13.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3302) Pirin PF02678.16 KXT06659.1 - 1.5e-26 92.4 0.4 2.8e-26 91.6 0.4 1.4 1 0 0 1 1 1 1 Pirin Pirin_C_2 PF17954.1 KXT06659.1 - 9.7e-10 38.5 0.0 2.5e-08 34.0 0.0 2.7 2 1 0 2 2 2 1 Quercetinase C-terminal cupin domain Cupin_2 PF07883.11 KXT06659.1 - 0.00071 19.2 2.9 0.0034 17.0 0.8 2.6 3 0 0 3 3 3 1 Cupin domain DUF2985 PF11204.8 KXT06660.1 - 6.8e-21 74.2 2.9 1.1e-20 73.6 2.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Phage_holin_3_6 PF07332.11 KXT06660.1 - 0.0087 16.1 0.4 0.096 12.7 0.1 2.1 2 0 0 2 2 2 1 Putative Actinobacterial Holin-X, holin superfamily III DUF4181 PF13789.6 KXT06660.1 - 0.045 14.0 2.1 0.055 13.7 0.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4181) N2227 PF07942.12 KXT06661.1 - 9.2e-95 316.9 0.0 1.1e-94 316.6 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_12 PF08242.12 KXT06661.1 - 0.00037 21.2 0.1 0.013 16.2 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXT06661.1 - 0.015 15.9 0.1 0.47 11.1 0.0 2.5 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 KXT06661.1 - 0.031 14.1 0.0 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 KXT06661.1 - 0.042 13.7 0.0 0.069 13.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain TPMT PF05724.11 KXT06661.1 - 0.068 12.8 0.0 0.32 10.6 0.0 2.0 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) adh_short PF00106.25 KXT06662.1 - 7.3e-40 136.5 0.1 9.7e-40 136.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT06662.1 - 1.2e-34 119.9 0.0 3.1e-34 118.6 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT06662.1 - 1.2e-06 28.6 0.6 1.2e-06 28.6 0.6 2.0 2 1 0 2 2 2 1 KR domain FAD_binding_3 PF01494.19 KXT06662.1 - 0.14 11.4 0.1 0.17 11.1 0.1 1.1 1 0 0 1 1 1 0 FAD binding domain 4HBT_3 PF13622.6 KXT06663.1 - 1.7e-85 287.2 0.0 2.7e-85 286.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KXT06663.1 - 7.5e-28 97.0 0.0 3.8e-13 49.4 0.0 4.2 3 1 0 3 3 3 3 Acyl-CoA thioesterase 4HBT PF03061.22 KXT06663.1 - 0.027 14.8 0.0 0.21 12.0 0.0 2.3 2 0 0 2 2 2 0 Thioesterase superfamily AAA_2 PF07724.14 KXT06664.1 - 9.5e-47 159.3 0.0 2.6e-45 154.6 0.0 3.0 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KXT06664.1 - 1.8e-33 114.6 2.7 1.8e-33 114.6 2.7 5.0 4 1 1 5 5 5 1 AAA lid domain AAA PF00004.29 KXT06664.1 - 1.5e-26 93.4 0.0 6.8e-14 52.4 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KXT06664.1 - 1.8e-24 85.6 0.6 7.7e-24 83.6 0.6 2.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KXT06664.1 - 7e-15 55.2 0.2 3.3e-09 36.9 0.0 3.3 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXT06664.1 - 7e-13 49.0 0.1 4.6e-05 23.7 0.0 4.6 2 1 1 3 3 3 2 AAA domain Clp_N PF02861.20 KXT06664.1 - 2.9e-10 40.1 2.1 0.013 15.7 0.0 4.2 3 0 0 3 3 3 2 Clp amino terminal domain, pathogenicity island component AAA_16 PF13191.6 KXT06664.1 - 5.2e-10 40.0 0.1 1.1e-06 29.1 0.1 5.7 4 3 1 6 6 5 2 AAA ATPase domain Sigma54_activat PF00158.26 KXT06664.1 - 2e-08 34.1 0.0 2.6e-05 24.0 0.0 2.7 2 1 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.17 KXT06664.1 - 8e-06 25.7 0.0 0.089 12.5 0.0 2.8 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_7 PF12775.7 KXT06664.1 - 8.1e-06 25.5 0.0 0.019 14.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_14 PF13173.6 KXT06664.1 - 8.5e-06 25.8 0.0 0.25 11.4 0.0 3.3 3 0 0 3 3 3 2 AAA domain Mg_chelatase PF01078.21 KXT06664.1 - 1.7e-05 24.3 0.2 0.11 11.9 0.1 3.6 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KXT06664.1 - 2.4e-05 24.5 1.3 0.27 11.4 0.0 3.5 3 1 0 3 3 2 2 AAA domain RNA_helicase PF00910.22 KXT06664.1 - 7.1e-05 23.2 0.0 0.56 10.6 0.0 2.7 2 0 0 2 2 2 2 RNA helicase ATPase_2 PF01637.18 KXT06664.1 - 8.6e-05 22.6 4.9 0.075 12.9 0.1 4.7 5 1 0 5 5 4 1 ATPase domain predominantly from Archaea AAA_30 PF13604.6 KXT06664.1 - 0.00012 21.9 0.0 0.98 9.1 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA_24 PF13479.6 KXT06664.1 - 0.00017 21.4 0.0 0.2 11.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 KXT06664.1 - 0.0003 20.8 0.0 0.47 10.5 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 KXT06664.1 - 0.00034 20.5 0.0 1.3 8.8 0.0 3.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 KXT06664.1 - 0.00037 20.4 0.0 0.7 9.8 0.0 3.2 2 1 0 2 2 2 1 RsgA GTPase AAA_19 PF13245.6 KXT06664.1 - 0.00044 20.6 0.8 0.24 11.7 0.2 3.8 3 1 0 3 3 3 1 AAA domain ABC_tran PF00005.27 KXT06664.1 - 0.00048 20.7 0.3 1 9.9 0.0 3.5 3 0 0 3 3 2 1 ABC transporter T2SSE PF00437.20 KXT06664.1 - 0.00068 18.8 0.3 0.015 14.4 0.0 3.0 3 0 0 3 3 3 1 Type II/IV secretion system protein RuvB_N PF05496.12 KXT06664.1 - 0.0012 18.6 2.3 7 6.4 0.9 4.4 3 1 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 KXT06664.1 - 0.0033 17.7 7.3 0.78 10.0 0.0 4.1 3 1 0 3 3 2 2 AAA domain AAA_18 PF13238.6 KXT06664.1 - 0.0044 17.6 12.3 0.14 12.7 0.0 4.5 4 1 0 4 4 2 2 AAA domain AAA_29 PF13555.6 KXT06664.1 - 0.006 16.3 0.0 5.6 6.8 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain NACHT PF05729.12 KXT06664.1 - 0.0061 16.5 0.0 0.54 10.1 0.0 2.8 2 0 0 2 2 2 1 NACHT domain Torsin PF06309.11 KXT06664.1 - 0.0072 16.4 0.0 0.037 14.1 0.0 2.1 2 0 0 2 2 1 1 Torsin SRP54 PF00448.22 KXT06664.1 - 0.0097 15.6 0.0 1.8 8.1 0.0 2.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 KXT06664.1 - 0.011 15.7 0.0 0.22 11.4 0.0 2.7 2 0 0 2 2 2 0 NTPase Roc PF08477.13 KXT06664.1 - 0.011 16.0 0.0 3.6 7.8 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ResIII PF04851.15 KXT06664.1 - 0.022 14.8 0.0 4.7 7.2 0.0 3.8 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Rad17 PF03215.15 KXT06664.1 - 0.051 13.5 0.0 11 5.9 0.0 2.6 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_25 PF13481.6 KXT06664.1 - 0.11 12.1 6.0 0.53 9.8 0.0 3.3 3 0 0 3 3 3 0 AAA domain CbiA PF01656.23 KXT06664.1 - 0.16 12.0 0.0 42 4.2 0.0 3.4 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain V_ATPase_I PF01496.19 KXT06664.1 - 0.31 8.9 10.1 0.044 11.7 6.0 1.7 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family AAA_23 PF13476.6 KXT06664.1 - 0.41 11.1 0.0 0.41 11.1 0.0 5.7 4 2 0 5 5 4 0 AAA domain Spc7 PF08317.11 KXT06664.1 - 10 4.9 20.2 23 3.7 20.2 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein Pkinase PF00069.25 KXT06665.1 - 1e-52 179.2 0.0 7e-50 169.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXT06665.1 - 1.7e-29 102.9 0.0 3.2e-28 98.7 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KXT06665.1 - 0.0014 18.0 0.0 0.0022 17.4 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KXT06665.1 - 0.0054 15.7 0.0 0.008 15.2 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 KXT06665.1 - 0.011 14.8 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 KXT06665.1 - 0.039 12.7 0.0 0.064 12.0 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KXT06665.1 - 0.047 13.6 0.1 1.2 9.1 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family XRCC4 PF06632.12 KXT06666.1 - 6e-13 48.3 2.2 7.8e-13 48.0 2.2 1.2 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 Cast PF10174.9 KXT06666.1 - 0.0034 15.7 4.5 0.0046 15.3 4.5 1.1 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone Phytase-like PF13449.6 KXT06667.1 - 9.5e-38 130.8 0.0 1.2e-37 130.4 0.0 1.2 1 0 0 1 1 1 1 Esterase-like activity of phytase SLT PF01464.20 KXT06668.1 - 0.057 13.1 0.1 0.13 12.0 0.1 1.7 1 1 0 1 1 1 0 Transglycosylase SLT domain Chitin_bind_1 PF00187.19 KXT06668.1 - 0.074 13.5 8.7 0.22 12.0 8.7 1.8 1 0 0 1 1 1 0 Chitin recognition protein HMGL-like PF00682.19 KXT06669.1 - 1.5e-78 264.0 0.0 9.1e-78 261.4 0.0 1.9 2 0 0 2 2 2 1 HMGL-like LeuA_dimer PF08502.10 KXT06669.1 - 3.4e-20 72.3 0.3 7.8e-20 71.1 0.3 1.6 1 1 0 1 1 1 1 LeuA allosteric (dimerisation) domain Sigma_reg_N PF13800.6 KXT06669.1 - 0.11 12.8 0.1 0.24 11.7 0.1 1.5 1 0 0 1 1 1 0 Sigma factor regulator N-terminal MAP65_ASE1 PF03999.12 KXT06670.1 - 7.1e-76 256.2 18.1 1e-75 255.6 16.9 1.8 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Spectrin PF00435.21 KXT06670.1 - 0.12 12.9 10.5 0.81 10.2 1.2 3.4 2 1 1 3 3 3 0 Spectrin repeat SKA2 PF16740.5 KXT06670.1 - 1.4 8.7 7.2 15 5.4 0.9 3.5 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 ING PF12998.7 KXT06670.1 - 2.8 8.6 8.7 0.84 10.3 3.1 2.9 2 1 1 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding F_bP_aldolase PF01116.20 KXT06671.1 - 8.3e-95 317.5 0.0 9.3e-95 317.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II MFS_1 PF07690.16 KXT06672.1 - 1.6e-26 93.0 38.2 1.8e-26 92.9 36.6 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXT06672.1 - 6.8e-14 51.6 7.3 4.6e-12 45.5 2.9 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter LacY_symp PF01306.19 KXT06672.1 - 0.00057 18.8 2.0 0.00057 18.8 2.0 1.6 2 0 0 2 2 2 1 LacY proton/sugar symporter TRI12 PF06609.13 KXT06672.1 - 0.0045 15.5 1.2 0.0072 14.8 1.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KXT06672.1 - 0.0086 14.4 4.7 0.21 9.8 0.4 3.0 2 2 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Barttin PF15462.6 KXT06673.1 - 0.017 14.9 6.2 0.23 11.2 1.4 2.4 1 1 1 2 2 2 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) DUF4939 PF16297.5 KXT06673.1 - 0.13 12.2 0.3 12 5.9 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4939) PAN_2 PF08276.11 KXT06674.1 - 0.0011 19.1 1.4 0.0021 18.2 1.4 1.4 1 0 0 1 1 1 1 PAN-like domain Fringe PF02434.16 KXT06674.1 - 0.002 17.6 3.2 0.0075 15.7 1.9 2.3 2 1 0 2 2 2 1 Fringe-like PAN_3 PF08277.12 KXT06674.1 - 0.0052 16.6 0.4 0.0093 15.8 0.4 1.3 1 0 0 1 1 1 1 PAN-like domain PAN_4 PF14295.6 KXT06674.1 - 0.065 13.1 1.2 0.14 12.1 1.2 1.5 1 0 0 1 1 1 0 PAN domain Glyco_transf_34 PF05637.12 KXT06674.1 - 0.53 10.0 5.3 0.84 9.3 5.3 1.2 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family Pga1 PF10333.9 KXT06678.1 - 1.9e-05 24.6 1.3 6.6e-05 22.8 1.3 1.9 1 1 0 1 1 1 1 GPI-Mannosyltransferase II co-activator AA_permease_2 PF13520.6 KXT06679.1 - 2.5e-86 290.2 40.8 3.1e-86 289.9 40.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXT06679.1 - 2.4e-18 66.0 34.8 5e-18 64.9 34.8 1.4 1 1 0 1 1 1 1 Amino acid permease p450 PF00067.22 KXT06680.1 - 3.7e-67 227.1 0.0 4.3e-67 226.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PsiF_repeat PF07769.14 KXT06680.1 - 1.1 9.1 3.6 0.43 10.5 0.2 2.1 3 0 0 3 3 3 0 psiF repeat Abhydrolase_6 PF12697.7 KXT06681.1 - 0.0031 18.1 0.6 0.017 15.7 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family LCAT PF02450.15 KXT06681.1 - 0.015 14.5 0.0 0.063 12.4 0.0 1.8 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 KXT06681.1 - 0.027 13.7 0.0 0.056 12.7 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF676 PF05057.14 KXT06681.1 - 0.052 13.1 0.0 0.089 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Palm_thioest PF02089.15 KXT06681.1 - 0.2 11.4 0.0 0.36 10.6 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Sulfotransfer_4 PF17784.1 KXT06682.1 - 1.8e-66 224.0 0.0 2.4e-66 223.6 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KXT06682.1 - 0.0068 16.8 0.2 0.031 14.7 0.0 2.2 1 1 1 2 2 2 1 Sulfotransferase family HEAT PF02985.22 KXT06684.1 - 8.7e-16 56.7 9.2 6.9e-06 25.9 0.1 9.9 12 0 0 12 12 11 2 HEAT repeat HEAT_EZ PF13513.6 KXT06684.1 - 7e-15 55.2 13.6 7.2e-10 39.2 0.0 8.6 8 2 2 10 10 10 2 HEAT-like repeat HEAT_2 PF13646.6 KXT06684.1 - 1.5e-11 44.5 12.4 0.0028 18.0 0.0 7.6 3 2 5 8 8 8 4 HEAT repeats IBN_N PF03810.19 KXT06684.1 - 1.2e-09 37.9 7.4 3.1e-08 33.4 0.3 4.6 4 0 0 4 4 4 1 Importin-beta N-terminal domain CLASP_N PF12348.8 KXT06684.1 - 1.9e-06 27.6 1.9 0.067 12.7 0.0 5.1 4 1 0 5 5 5 2 CLASP N terminal Arm PF00514.23 KXT06684.1 - 3e-05 23.9 5.1 9.1 6.5 0.0 6.1 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.16 KXT06684.1 - 0.00032 21.1 0.1 6.6 7.7 0.0 5.9 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat UME PF08064.13 KXT06684.1 - 0.00095 19.0 1.5 4.4 7.3 0.0 5.5 4 2 2 6 6 6 1 UME (NUC010) domain DUF3385 PF11865.8 KXT06684.1 - 0.0018 18.2 2.7 2.8 7.8 0.0 4.9 3 2 1 4 4 4 1 Domain of unknown function (DUF3385) Cnd1 PF12717.7 KXT06684.1 - 0.0027 17.8 1.2 0.014 15.5 0.1 2.8 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.12 KXT06684.1 - 0.012 15.3 3.9 0.18 11.6 0.1 3.8 3 2 1 4 4 4 0 rRNA processing/ribosome biogenesis ThylakoidFormat PF11264.8 KXT06684.1 - 0.1 12.3 0.5 3.1 7.4 0.1 3.3 2 1 1 3 3 3 0 Thylakoid formation protein FAD_binding_4 PF01565.23 KXT06685.1 - 5e-22 78.1 2.2 9.5e-22 77.2 1.5 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KXT06685.1 - 4.7e-06 26.6 0.4 2e-05 24.6 0.2 2.1 2 0 0 2 2 2 1 Berberine and berberine like AA_permease_2 PF13520.6 KXT06686.1 - 1.4e-62 211.9 49.5 2e-62 211.4 49.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXT06686.1 - 1.7e-18 66.5 42.1 2.4e-18 66.0 42.1 1.1 1 0 0 1 1 1 1 Amino acid permease SpoVAB PF13782.6 KXT06686.1 - 0.013 15.8 0.1 0.013 15.8 0.1 3.6 4 0 0 4 4 4 0 Stage V sporulation protein AB DUF1980 PF09323.10 KXT06686.1 - 6.5 6.6 8.8 19 5.1 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) Prefoldin_2 PF01920.20 KXT06687.1 - 4.3e-21 74.9 3.3 2.8e-18 65.8 1.5 2.2 1 1 1 2 2 2 2 Prefoldin subunit bZIP_1 PF00170.21 KXT06687.1 - 0.012 15.7 0.2 0.012 15.7 0.2 2.6 2 1 0 2 2 2 0 bZIP transcription factor PP_kinase_N PF13089.6 KXT06687.1 - 0.054 13.8 1.6 0.3 11.4 0.0 2.2 2 1 0 2 2 2 0 Polyphosphate kinase N-terminal domain DUF5082 PF16888.5 KXT06687.1 - 0.31 11.3 7.0 3.5 7.9 7.0 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) RRM_1 PF00076.22 KXT06689.1 - 6.3e-46 154.1 1.7 3e-20 71.8 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 KXT06689.1 - 3.2e-21 76.2 0.8 3.2e-20 73.0 0.8 2.7 1 1 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_3 PF08777.11 KXT06689.1 - 5.3e-06 26.4 2.4 0.045 13.8 0.0 3.7 4 0 0 4 4 4 2 RNA binding motif RRM_7 PF16367.5 KXT06689.1 - 0.0097 16.0 0.1 2.1 8.5 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif RRM_5 PF13893.6 KXT06689.1 - 0.017 14.7 0.0 0.22 11.1 0.0 2.2 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KXT06689.1 - 0.048 13.9 1.2 0.36 11.1 0.3 3.0 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter RRM_occluded PF16842.5 KXT06689.1 - 0.083 12.8 0.0 0.74 9.7 0.0 2.3 2 0 0 2 2 2 0 Occluded RNA-recognition motif RRM_1 PF00076.22 KXT06690.1 - 8.2e-46 153.7 1.7 3.3e-20 71.7 0.1 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 KXT06690.1 - 3.8e-21 76.0 0.8 3.5e-20 72.9 0.8 2.6 1 1 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_3 PF08777.11 KXT06690.1 - 3.7e-06 26.9 1.6 0.05 13.7 0.0 3.8 4 0 0 4 4 4 2 RNA binding motif RRM_7 PF16367.5 KXT06690.1 - 0.012 15.7 0.1 2.3 8.4 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif RRM_5 PF13893.6 KXT06690.1 - 0.02 14.5 0.0 0.25 11.0 0.0 2.2 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KXT06690.1 - 0.05 13.8 1.1 0.4 10.9 0.3 3.0 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter RRM_occluded PF16842.5 KXT06690.1 - 0.098 12.5 0.0 0.82 9.6 0.0 2.3 2 0 0 2 2 2 0 Occluded RNA-recognition motif Blt1 PF12754.7 KXT06691.1 - 0.12 12.7 0.3 0.32 11.3 0.3 1.8 1 0 0 1 1 1 0 Blt1 N-terminal domain Aminotran_3 PF00202.21 KXT06692.1 - 1.6e-77 260.9 0.0 2.2e-77 260.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III PAC4 PF16093.5 KXT06693.1 - 2.5e-25 88.5 0.4 3.4e-25 88.0 0.4 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 VEFS-Box PF09733.9 KXT06694.1 - 2.3e-07 30.7 0.0 5.2e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 VEFS-Box of polycomb protein PHD PF00628.29 KXT06694.1 - 0.00081 19.2 4.9 0.00081 19.2 4.9 1.9 2 0 0 2 2 2 1 PHD-finger FANCL_C PF11793.8 KXT06694.1 - 0.0019 18.3 0.5 0.0053 16.9 0.5 1.7 1 0 0 1 1 1 1 FANCL C-terminal domain zf-HC5HC2H PF13771.6 KXT06694.1 - 0.0082 16.4 1.1 0.043 14.1 0.5 2.2 2 0 0 2 2 2 1 PHD-like zinc-binding domain PGAP1 PF07819.13 KXT06695.1 - 4.7e-89 298.1 0.0 7.6e-89 297.4 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KXT06695.1 - 0.00036 21.2 1.1 0.00065 20.4 0.1 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXT06695.1 - 0.0018 17.6 0.0 0.0037 16.5 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KXT06695.1 - 0.023 14.4 0.0 0.062 12.9 0.0 1.7 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF676 PF05057.14 KXT06695.1 - 0.027 14.0 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Palm_thioest PF02089.15 KXT06695.1 - 0.071 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Palmitoyl protein thioesterase LCAT PF02450.15 KXT06695.1 - 0.14 11.3 0.0 0.28 10.3 0.0 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase OSTbeta PF15048.6 KXT06695.1 - 5 7.3 5.3 2.2 8.5 0.1 2.5 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein Shugoshin_C PF07557.11 KXT06696.1 - 0.056 13.3 0.7 0.14 12.0 0.7 1.7 1 0 0 1 1 1 0 Shugoshin C terminus Tankyrase_bdg_C PF15327.6 KXT06696.1 - 0.34 11.4 3.4 0.76 10.2 3.4 1.6 1 0 0 1 1 1 0 Tankyrase binding protein C terminal domain Ras PF00071.22 KXT06698.1 - 1.1e-64 216.9 0.6 1.5e-64 216.5 0.6 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXT06698.1 - 3.1e-35 121.0 0.1 5.6e-35 120.2 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXT06698.1 - 1.3e-15 57.2 0.1 1.9e-15 56.7 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KXT06698.1 - 9.7e-05 22.3 0.4 0.34 10.8 0.0 2.3 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KXT06698.1 - 0.0001 22.3 0.0 0.00044 20.3 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KXT06698.1 - 0.00021 20.9 0.3 0.00049 19.7 0.2 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KXT06698.1 - 0.00088 18.7 0.1 0.0013 18.2 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KXT06698.1 - 0.0021 17.5 0.1 0.0037 16.7 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.29 KXT06698.1 - 0.0089 16.5 0.1 0.6 10.5 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 KXT06698.1 - 0.022 14.3 0.0 0.1 12.1 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_16 PF13191.6 KXT06698.1 - 0.028 14.8 0.0 0.062 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KXT06698.1 - 0.1 12.9 0.0 0.24 11.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KXT06698.1 - 0.13 12.1 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 KXT06698.1 - 0.16 11.9 0.0 0.48 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Tubulin PF00091.25 KXT06699.1 - 1.4e-65 221.2 0.0 1.9e-65 220.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KXT06699.1 - 1.3e-50 170.8 0.1 2.1e-50 170.1 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KXT06699.1 - 0.002 17.8 0.0 0.005 16.5 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain WW PF00397.26 KXT06700.1 - 6e-11 42.2 0.4 1.3e-10 41.2 0.4 1.6 1 0 0 1 1 1 1 WW domain WW PF00397.26 KXT06701.1 - 6.8e-06 26.1 0.1 1.5e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 WW domain RabGAP-TBC PF00566.18 KXT06702.1 - 9.2e-23 81.0 0.0 1.3e-22 80.5 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RNase_PH PF01138.21 KXT06702.1 - 0.16 12.5 0.0 0.28 11.7 0.0 1.3 1 0 0 1 1 1 0 3' exoribonuclease family, domain 1 Utp8 PF10395.9 KXT06703.1 - 1.5e-06 27.1 0.0 3.3e-05 22.6 0.0 2.6 2 1 0 2 2 2 1 Utp8 family DUF1840 PF08895.11 KXT06703.1 - 0.057 13.7 0.3 0.057 13.7 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) PTPLA PF04387.14 KXT06704.1 - 4.8e-57 192.3 11.9 7.5e-57 191.6 11.9 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA GDPD PF03009.17 KXT06704.1 - 2e-15 57.2 0.0 3.1e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Utp8 PF10395.9 KXT06705.1 - 1.5e-06 27.1 0.0 3.3e-05 22.6 0.0 2.6 2 1 0 2 2 2 1 Utp8 family DUF1840 PF08895.11 KXT06705.1 - 0.057 13.7 0.3 0.057 13.7 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) SSF PF00474.17 KXT06706.1 - 1.7e-21 76.5 27.8 2.5e-21 76.0 27.8 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family DUF1072 PF06380.11 KXT06706.1 - 0.34 10.8 3.3 1.2 9.1 0.6 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) GATA PF00320.27 KXT06707.1 - 1e-14 53.8 1.3 1.7e-14 53.1 1.3 1.4 1 0 0 1 1 1 1 GATA zinc finger Tropomyosin PF00261.20 KXT06707.1 - 0.0058 16.0 7.1 0.0083 15.5 7.1 1.1 1 0 0 1 1 1 1 Tropomyosin ATG16 PF08614.11 KXT06707.1 - 0.012 15.8 3.9 0.012 15.8 3.9 1.7 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Pox_A_type_inc PF04508.12 KXT06707.1 - 0.12 12.3 1.6 15 5.7 0.0 3.1 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat TF_Zn_Ribbon PF08271.12 KXT06707.1 - 0.24 11.0 0.3 0.42 10.2 0.3 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding GAS PF13851.6 KXT06707.1 - 0.24 10.7 3.8 0.34 10.2 3.8 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 KXT06707.1 - 0.35 10.9 7.5 0.12 12.4 3.1 1.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Golgin_A5 PF09787.9 KXT06707.1 - 0.43 10.0 4.9 0.63 9.4 4.9 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 KLRAQ PF10205.9 KXT06707.1 - 0.81 10.0 4.8 1.1 9.6 3.5 1.8 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein Atg14 PF10186.9 KXT06707.1 - 2.5 7.1 5.5 4.4 6.3 5.5 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 JIP_LZII PF16471.5 KXT06707.1 - 4.6 7.5 6.7 19 5.5 6.7 1.9 1 1 0 1 1 1 0 JNK-interacting protein leucine zipper II DIOX_N PF14226.6 KXT06708.1 - 9.5e-29 100.6 0.0 1.8e-28 99.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXT06708.1 - 7.1e-24 84.2 0.0 2.8e-23 82.3 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily SUIM_assoc PF16619.5 KXT06708.1 - 0.062 13.4 1.9 0.16 12.0 1.9 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 F-box PF00646.33 KXT06710.1 - 1e-06 28.5 2.7 0.0012 18.7 0.3 2.2 2 0 0 2 2 2 2 F-box domain F-box-like PF12937.7 KXT06710.1 - 0.00042 20.1 1.9 0.25 11.3 0.1 2.3 2 0 0 2 2 2 2 F-box-like RF-1 PF00472.20 KXT06711.1 - 1.1e-26 93.0 1.5 1.7e-26 92.4 1.5 1.2 1 0 0 1 1 1 1 RF-1 domain Prp19 PF08606.11 KXT06712.1 - 3.7e-32 110.1 2.7 7.8e-31 105.9 3.4 2.2 2 0 0 2 2 2 1 Prp19/Pso4-like WD40 PF00400.32 KXT06712.1 - 1.8e-17 63.4 1.4 1.3e-05 25.9 0.0 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXT06712.1 - 1.3e-13 51.0 0.0 3.7e-07 30.4 0.0 4.8 1 1 4 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXT06712.1 - 0.00024 21.0 0.0 0.01 15.7 0.0 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A V_ATPase_I_N PF18670.1 KXT06712.1 - 0.0044 17.4 0.1 0.01 16.2 0.1 1.6 1 0 0 1 1 1 1 V-type ATPase subunit I, N-terminal domain U-box PF04564.15 KXT06712.1 - 0.0045 17.1 0.0 0.0086 16.2 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 KXT06712.1 - 0.0073 16.1 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Cytochrom_D1 PF02239.16 KXT06712.1 - 0.0089 14.6 0.0 0.039 12.5 0.0 1.9 2 1 0 2 2 2 1 Cytochrome D1 heme domain DUF3450 PF11932.8 KXT06712.1 - 0.018 14.4 1.2 0.034 13.4 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) VID27 PF08553.10 KXT06712.1 - 0.02 13.9 0.0 0.036 13.1 0.0 1.3 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain Ge1_WD40 PF16529.5 KXT06712.1 - 0.029 13.3 0.0 0.07 12.1 0.0 1.6 1 1 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4407 PF14362.6 KXT06712.1 - 0.034 13.5 2.2 0.049 13.0 2.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Lactonase PF10282.9 KXT06712.1 - 0.057 12.7 0.3 1.4 8.1 0.0 2.4 2 1 1 3 3 3 0 Lactonase, 7-bladed beta-propeller Frtz PF11768.8 KXT06712.1 - 0.062 11.6 0.0 0.098 11.0 0.0 1.2 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz FixH PF05751.11 KXT06712.1 - 0.078 13.0 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 FixH ABC_tran_CTD PF16326.5 KXT06712.1 - 0.13 12.5 1.5 0.34 11.2 1.5 1.6 1 0 0 1 1 1 0 ABC transporter C-terminal domain Prp19 PF08606.11 KXT06713.1 - 3.7e-32 110.1 2.7 7.8e-31 105.9 3.4 2.2 2 0 0 2 2 2 1 Prp19/Pso4-like WD40 PF00400.32 KXT06713.1 - 1.8e-17 63.4 1.4 1.3e-05 25.9 0.0 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXT06713.1 - 1.3e-13 51.0 0.0 3.7e-07 30.4 0.0 4.8 1 1 4 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KXT06713.1 - 0.00024 21.0 0.0 0.01 15.7 0.0 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A V_ATPase_I_N PF18670.1 KXT06713.1 - 0.0044 17.4 0.1 0.01 16.2 0.1 1.6 1 0 0 1 1 1 1 V-type ATPase subunit I, N-terminal domain U-box PF04564.15 KXT06713.1 - 0.0045 17.1 0.0 0.0086 16.2 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 KXT06713.1 - 0.0073 16.1 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Cytochrom_D1 PF02239.16 KXT06713.1 - 0.0089 14.6 0.0 0.039 12.5 0.0 1.9 2 1 0 2 2 2 1 Cytochrome D1 heme domain DUF3450 PF11932.8 KXT06713.1 - 0.018 14.4 1.2 0.034 13.4 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) VID27 PF08553.10 KXT06713.1 - 0.02 13.9 0.0 0.036 13.1 0.0 1.3 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain Ge1_WD40 PF16529.5 KXT06713.1 - 0.029 13.3 0.0 0.07 12.1 0.0 1.6 1 1 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4407 PF14362.6 KXT06713.1 - 0.034 13.5 2.2 0.049 13.0 2.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Lactonase PF10282.9 KXT06713.1 - 0.057 12.7 0.3 1.4 8.1 0.0 2.4 2 1 1 3 3 3 0 Lactonase, 7-bladed beta-propeller Frtz PF11768.8 KXT06713.1 - 0.062 11.6 0.0 0.098 11.0 0.0 1.2 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz FixH PF05751.11 KXT06713.1 - 0.078 13.0 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 FixH ABC_tran_CTD PF16326.5 KXT06713.1 - 0.13 12.5 1.5 0.34 11.2 1.5 1.6 1 0 0 1 1 1 0 ABC transporter C-terminal domain Methyltransf_23 PF13489.6 KXT06715.1 - 7.9e-21 74.6 0.0 1.1e-20 74.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXT06715.1 - 6.3e-11 42.8 0.0 2.6e-10 40.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXT06715.1 - 1.2e-08 35.6 0.0 5.4e-08 33.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXT06715.1 - 1.9e-07 31.0 0.0 0.0021 17.8 0.0 2.6 2 1 1 3 3 3 2 Methyltransferase domain Methyltransf_11 PF08241.12 KXT06715.1 - 5.3e-07 30.2 0.0 1.2e-06 29.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KXT06715.1 - 0.00041 19.9 0.0 0.00072 19.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 KXT06715.1 - 0.023 14.4 0.0 0.049 13.4 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase PrmA PF06325.13 KXT06715.1 - 0.025 14.0 0.0 0.055 12.8 0.0 1.6 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 KXT06715.1 - 0.031 13.8 0.0 0.081 12.4 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase IGR PF09597.10 KXT06715.1 - 0.087 12.9 0.2 0.26 11.4 0.1 1.9 2 0 0 2 2 2 0 IGR protein motif FtsJ PF01728.19 KXT06715.1 - 0.12 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF938 PF06080.12 KXT06715.1 - 0.22 11.3 0.0 1 9.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF938) GST_N PF02798.20 KXT06716.1 - 5.1e-08 33.2 0.0 1.9e-07 31.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXT06716.1 - 2.8e-06 27.3 0.0 1.2e-05 25.2 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXT06716.1 - 3.6e-06 27.1 0.0 6.4e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KXT06716.1 - 1.8e-05 25.0 0.0 6.7e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXT06716.1 - 4.5e-05 23.8 0.0 9.4e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 KXT06716.1 - 0.00072 20.1 0.0 0.0013 19.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KXT06716.1 - 0.027 14.7 0.0 0.053 13.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain CDP-OH_P_transf PF01066.21 KXT06717.1 - 2.3e-11 44.3 0.2 2.3e-11 44.3 0.2 2.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Thermopsin PF05317.11 KXT06717.1 - 0.073 12.5 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Thermopsin CDP-OH_P_transf PF01066.21 KXT06718.1 - 2.3e-11 44.3 0.2 2.3e-11 44.3 0.2 2.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Thermopsin PF05317.11 KXT06718.1 - 0.073 12.5 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Thermopsin CDP-OH_P_transf PF01066.21 KXT06719.1 - 2.3e-11 44.3 0.2 2.3e-11 44.3 0.2 2.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Thermopsin PF05317.11 KXT06719.1 - 0.073 12.5 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Thermopsin TPT PF03151.16 KXT06720.1 - 6.7e-54 183.2 8.6 8e-54 182.9 8.6 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KXT06720.1 - 5e-11 42.3 9.9 1.1e-10 41.2 9.9 1.5 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 KXT06720.1 - 5e-06 26.7 30.3 0.0011 19.1 9.5 3.6 2 1 0 2 2 2 2 EamA-like transporter family Mem_trans PF03547.18 KXT06723.1 - 1.1e-43 149.1 7.3 2.9e-43 147.8 7.3 1.5 1 1 0 1 1 1 1 Membrane transport protein Mg_trans_NIPA PF05653.14 KXT06724.1 - 1.4e-102 342.8 16.1 1.6e-102 342.6 16.1 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KXT06724.1 - 8.8e-06 25.9 6.3 8.8e-06 25.9 6.3 3.3 3 0 0 3 3 3 1 EamA-like transporter family BTB_2 PF02214.22 KXT06725.1 - 0.00011 22.5 0.1 0.59 10.5 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain UBX PF00789.20 KXT06726.1 - 1.7e-12 47.4 0.0 5e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 KXT06726.1 - 4.5e-10 39.2 2.0 4.5e-10 39.2 2.0 1.9 2 0 0 2 2 2 1 UBA-like domain TAP_C PF03943.13 KXT06726.1 - 0.022 14.4 0.3 0.05 13.2 0.3 1.5 1 0 0 1 1 1 0 TAP C-terminal domain DUF1682 PF07946.14 KXT06726.1 - 0.29 10.3 13.9 0.5 9.5 13.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Med19 PF10278.9 KXT06726.1 - 0.44 10.5 7.0 0.68 9.8 7.0 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 RR_TM4-6 PF06459.12 KXT06726.1 - 0.84 9.4 11.1 1.3 8.7 11.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.17 KXT06726.1 - 0.88 9.7 4.2 1.3 9.1 4.2 1.2 1 0 0 1 1 1 0 DDHD domain MRP-S27 PF10037.9 KXT06726.1 - 1.7 7.4 11.1 3.5 6.4 11.1 1.5 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 DUF4746 PF15928.5 KXT06726.1 - 1.8 7.9 10.5 3.1 7.2 10.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RPN2_C PF18004.1 KXT06726.1 - 2 8.3 15.3 3.7 7.4 15.3 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Hox9_act PF04617.13 KXT06726.1 - 2.4 8.9 6.1 4.8 7.9 6.1 1.4 1 0 0 1 1 1 0 Hox9 activation region V_ATPase_I PF01496.19 KXT06726.1 - 2.6 5.8 4.6 3.4 5.5 4.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ald_Xan_dh_C2 PF02738.18 KXT06727.1 - 3.8e-198 659.4 0.3 5.3e-198 658.9 0.3 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 KXT06727.1 - 2.3e-36 125.1 0.0 4.9e-36 124.0 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 KXT06727.1 - 7.3e-29 100.3 0.1 1.4e-28 99.4 0.1 1.5 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.17 KXT06727.1 - 1.2e-28 99.3 0.0 7.4e-28 96.8 0.0 2.3 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.20 KXT06727.1 - 2e-25 88.6 0.0 4.6e-25 87.5 0.0 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 KXT06727.1 - 1.4e-08 34.5 1.6 2.3e-08 33.9 0.0 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain AAA PF00004.29 KXT06731.1 - 4.1e-11 43.4 4.5 2.7e-10 40.8 2.4 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KXT06731.1 - 6.8e-06 26.1 0.1 0.0016 18.4 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 KXT06731.1 - 1e-05 26.0 0.0 3.5e-05 24.2 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 KXT06731.1 - 0.00032 20.0 0.0 0.00054 19.3 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 KXT06731.1 - 0.001 19.3 0.2 0.0065 16.8 0.2 2.2 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KXT06731.1 - 0.0015 18.3 0.0 0.0038 17.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KXT06731.1 - 0.0043 17.0 0.1 0.11 12.4 0.0 2.9 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KXT06731.1 - 0.0053 17.3 0.0 0.042 14.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 KXT06731.1 - 0.033 14.1 0.0 3.4 7.6 0.0 2.3 2 0 0 2 2 2 0 NTPase TsaE PF02367.17 KXT06731.1 - 0.062 13.3 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KXT06731.1 - 0.21 12.0 0.0 0.56 10.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.6 KXT06731.1 - 0.41 11.1 0.0 0.41 11.1 0.0 2.6 3 0 0 3 3 2 0 AAA domain RRM_1 PF00076.22 KXT06732.1 - 6.3e-14 51.6 0.6 1.5e-13 50.4 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAP2 PF01569.21 KXT06733.1 - 9.7e-11 41.6 3.9 1.3e-10 41.2 2.7 1.8 1 1 0 1 1 1 1 PAP2 superfamily MIG-14_Wnt-bd PF06664.12 KXT06733.1 - 0.0082 15.4 0.2 0.018 14.3 0.2 1.4 1 1 0 1 1 1 1 Wnt-binding factor required for Wnt secretion DUF212 PF02681.14 KXT06733.1 - 0.019 15.1 0.0 0.41 10.8 0.0 2.3 2 1 0 2 2 2 0 Divergent PAP2 family NmrA PF05368.13 KXT06734.1 - 1.5e-32 113.0 0.0 2e-32 112.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KXT06734.1 - 1.9e-13 50.7 0.0 7.9e-13 48.7 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXT06734.1 - 5.5e-07 29.3 0.0 1.5e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXT06734.1 - 2.9e-06 26.5 0.0 4.2e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 KXT06734.1 - 0.00029 20.8 0.0 0.00052 20.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KXT06734.1 - 0.00084 19.6 0.1 0.0022 18.3 0.1 1.7 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KXT06734.1 - 0.0062 17.0 0.0 0.018 15.4 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 KXT06734.1 - 0.0083 15.6 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KXT06734.1 - 0.014 14.6 0.1 0.02 14.0 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Radical_SAM PF04055.21 KXT06734.1 - 0.026 14.9 0.0 1 9.7 0.0 2.3 1 1 1 2 2 2 0 Radical SAM superfamily DapB_N PF01113.20 KXT06734.1 - 0.03 14.4 0.0 0.058 13.5 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus PrpR_N PF06506.11 KXT06734.1 - 0.046 13.3 0.1 0.14 11.7 0.0 1.9 2 0 0 2 2 2 0 Propionate catabolism activator adh_short PF00106.25 KXT06734.1 - 0.074 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase DXP_reductoisom PF02670.16 KXT06734.1 - 0.086 13.6 0.1 0.2 12.4 0.1 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Longin PF13774.6 KXT06735.1 - 5.3e-22 77.7 0.2 9e-22 76.9 0.2 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 KXT06735.1 - 1.2e-06 28.3 1.0 8e-06 25.6 0.1 2.1 2 0 0 2 2 2 1 Synaptobrevin DUF4404 PF14357.6 KXT06735.1 - 0.017 15.7 1.0 0.47 11.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) OST-HTH PF12872.7 KXT06735.1 - 0.068 13.0 0.4 2.8 7.8 0.1 2.4 2 0 0 2 2 2 0 OST-HTH/LOTUS domain Acetyltransf_10 PF13673.7 KXT06736.1 - 2.3e-08 34.0 0.0 3.6e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KXT06736.1 - 2.4e-07 31.1 0.0 4.8e-07 30.1 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KXT06736.1 - 1.8e-06 28.2 0.0 3.1e-06 27.4 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KXT06736.1 - 0.00078 19.4 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KXT06736.1 - 0.0011 19.1 0.0 0.0017 18.4 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 KXT06736.1 - 0.0066 16.5 0.0 0.23 11.5 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain zf-RRN7 PF11781.8 KXT06736.1 - 0.24 11.1 1.4 0.72 9.6 1.2 1.8 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Fungal_trans PF04082.18 KXT06737.1 - 8.8e-22 77.4 0.7 1.5e-21 76.6 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT06737.1 - 4.1e-07 30.0 7.6 7.2e-07 29.2 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 KXT06738.1 - 1.2e-22 80.4 0.0 1.7e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT06738.1 - 1e-15 57.9 0.0 1.3e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF3879 PF12995.7 KXT06738.1 - 0.0041 16.9 0.0 0.0059 16.3 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function, E. rectale Gene description (DUF3879) adh_short PF00106.25 KXT06739.1 - 1.2e-18 67.3 0.2 1.4e-18 67.1 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT06739.1 - 4.7e-12 46.0 0.1 5.8e-12 45.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KXT06739.1 - 2.7e-06 27.4 0.1 3e-06 27.2 0.1 1.0 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXT06739.1 - 1.4e-05 24.7 0.0 1.5e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KXT06739.1 - 8.1e-05 22.6 0.1 0.00013 21.9 0.1 1.3 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 KXT06739.1 - 0.00038 19.7 0.1 0.00043 19.5 0.1 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KXT06739.1 - 0.012 15.0 0.1 0.013 14.9 0.1 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KXT06740.1 - 8.7e-47 159.1 0.1 1.1e-46 158.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT06740.1 - 9.2e-33 113.7 0.1 1.2e-32 113.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT06740.1 - 3.7e-07 30.2 0.1 8.1e-07 29.1 0.1 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXT06740.1 - 8.4e-07 28.7 0.1 2.7e-06 27.0 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KXT06740.1 - 1.2e-06 27.9 0.1 2.2e-06 27.0 0.1 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KXT06740.1 - 5.4e-06 26.4 0.3 7.4e-06 26.0 0.3 1.3 1 1 0 1 1 1 1 NAD(P)H-binding DUF3879 PF12995.7 KXT06740.1 - 0.0072 16.1 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function, E. rectale Gene description (DUF3879) GDP_Man_Dehyd PF16363.5 KXT06740.1 - 0.015 14.7 0.1 0.031 13.7 0.1 1.6 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Glyco_hydro_125 PF06824.11 KXT06742.1 - 9.7e-183 607.8 0.0 1.1e-182 607.6 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) DEK_C PF08766.11 KXT06742.1 - 3.3 7.7 4.6 47 4.0 0.1 3.3 4 0 0 4 4 4 0 DEK C terminal domain Methyltransf_32 PF13679.6 KXT06743.1 - 0.013 15.5 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 KXT06743.1 - 0.044 13.5 0.0 0.078 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.11 KXT06743.1 - 0.049 12.6 0.0 0.12 11.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.6 KXT06743.1 - 0.1 13.3 0.0 1.1 10.1 0.0 2.6 3 1 1 4 4 4 0 Methyltransferase domain MTS PF05175.14 KXT06743.1 - 0.13 11.8 0.0 0.38 10.3 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_31 PF13847.6 KXT06743.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 KXT06743.1 - 0.14 12.3 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase TPD PF14811.6 KXT06744.1 - 0.091 12.6 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function TPD sequence-motif MmgE_PrpD PF03972.14 KXT06753.1 - 1.4e-115 386.4 4.5 1.6e-115 386.2 4.5 1.0 1 0 0 1 1 1 1 MmgE/PrpD family SPOR PF05036.13 KXT06753.1 - 0.096 13.1 0.3 0.31 11.4 0.0 1.9 2 0 0 2 2 2 0 Sporulation related domain Ig_6 PF18452.1 KXT06755.1 - 0.0065 16.0 0.0 0.0094 15.5 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain Ntox16 PF15523.6 KXT06758.1 - 0.041 14.1 0.3 0.065 13.5 0.3 1.2 1 0 0 1 1 1 0 Novel toxin 16 TPPK_C PF12555.8 KXT06758.1 - 0.13 12.4 1.1 0.2 11.7 1.1 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal Cwf_Cwc_15 PF04889.12 KXT06759.1 - 0.0026 17.5 18.1 0.0031 17.3 18.1 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Sporozoite_P67 PF05642.11 KXT06759.1 - 0.04 12.0 6.8 0.045 11.8 6.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BUD22 PF09073.10 KXT06759.1 - 0.1 11.9 19.9 0.12 11.7 19.9 1.1 1 0 0 1 1 1 0 BUD22 RNA_pol_3_Rpc31 PF11705.8 KXT06759.1 - 0.15 12.3 24.7 0.24 11.6 24.7 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 GCIP PF13324.6 KXT06759.1 - 0.32 10.6 4.4 0.37 10.3 4.4 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting NOA36 PF06524.12 KXT06759.1 - 0.47 9.7 18.0 0.67 9.2 18.0 1.3 1 0 0 1 1 1 0 NOA36 protein Polyoma_lg_T_C PF06431.11 KXT06759.1 - 0.62 8.9 3.5 0.74 8.6 3.5 1.2 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus DNA_pol_phi PF04931.13 KXT06759.1 - 0.74 7.8 20.2 0.98 7.4 20.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi Rhabdo_ncap PF00945.18 KXT06759.1 - 1.2 7.9 5.4 1.4 7.7 5.4 1.2 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein CENP-B_dimeris PF09026.10 KXT06759.1 - 1.6 9.2 21.7 4.2 7.8 21.7 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nop14 PF04147.12 KXT06759.1 - 2.8 6.0 26.2 3.3 5.8 26.2 1.0 1 0 0 1 1 1 0 Nop14-like family RXT2_N PF08595.11 KXT06759.1 - 3.5 7.6 14.8 5.8 6.9 14.7 1.5 1 1 0 1 1 1 0 RXT2-like, N-terminal TFIIA PF03153.13 KXT06759.1 - 6 6.7 17.4 7.3 6.5 17.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LRIF1 PF15741.5 KXT06759.1 - 6.4 5.2 7.8 7.9 4.9 7.8 1.0 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 Helitron_like_N PF14214.6 KXT06760.1 - 0.0055 16.9 0.0 0.0065 16.7 0.0 1.0 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus JmjC PF02373.22 KXT06762.1 - 1.4e-08 35.1 0.3 9.9e-08 32.4 0.3 2.3 1 1 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.9 KXT06762.1 - 1.3e-06 28.6 10.3 1.3e-06 28.6 10.3 2.5 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.11 KXT06762.1 - 0.0033 17.1 0.0 0.0083 15.8 0.0 1.6 1 0 0 1 1 1 1 Cupin domain Ferric_reduct PF01794.19 KXT06765.1 - 4.3e-22 78.6 10.9 4.3e-22 78.6 10.9 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KXT06765.1 - 9.3e-05 22.5 0.0 0.00052 20.1 0.0 2.4 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KXT06765.1 - 0.00058 20.0 1.5 0.072 13.2 0.2 3.2 2 1 1 3 3 3 1 Ferric reductase NAD binding domain DUF5463 PF17551.2 KXT06765.1 - 0.083 12.8 3.3 0.26 11.2 3.3 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5463) DUF3984 PF13136.6 KXT06766.1 - 1.1e-24 87.5 33.7 9.1e-23 81.2 25.7 3.0 2 1 1 3 3 3 2 Protein of unknown function (DUF3984) PNGaseA PF12222.8 KXT06767.1 - 3.1e-153 510.7 2.7 3.1e-153 510.7 2.7 1.4 2 0 0 2 2 2 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A CAP_N PF01213.19 KXT06768.1 - 0.073 12.5 1.1 0.075 12.5 1.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Orbi_VP7 PF00897.17 KXT06768.1 - 0.22 10.5 0.1 0.23 10.4 0.1 1.0 1 0 0 1 1 1 0 Orbivirus inner capsid protein VP7 DUF2613 PF11021.8 KXT06773.1 - 0.0014 18.7 1.0 0.0023 18.0 1.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2613) SKG6 PF08693.10 KXT06773.1 - 0.009 15.4 4.2 0.014 14.8 4.2 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain COPI_assoc PF08507.10 KXT06773.1 - 0.1 12.7 0.1 0.12 12.4 0.1 1.1 1 0 0 1 1 1 0 COPI associated protein HET PF06985.11 KXT06774.1 - 6.6e-27 94.7 1.5 4.7e-26 91.9 1.5 2.1 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SPRY PF00622.28 KXT06774.1 - 0.073 13.2 0.1 11 6.2 0.0 3.4 4 0 0 4 4 4 0 SPRY domain DUF917 PF06032.12 KXT06775.1 - 4e-102 341.6 0.1 8.5e-102 340.6 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.18 KXT06775.1 - 4.5e-31 108.2 2.6 1.4e-26 93.5 0.4 3.3 2 1 1 3 3 3 3 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KXT06775.1 - 6e-27 94.5 8.0 2.7e-26 92.4 0.1 3.9 4 1 0 4 4 4 1 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.6 KXT06775.1 - 0.006 15.2 0.8 1.2 7.7 0.1 2.4 2 0 0 2 2 2 2 MutL protein FtsA PF14450.6 KXT06775.1 - 0.0087 16.5 0.1 0.0087 16.5 0.1 3.4 4 1 0 4 4 4 1 Cell division protein FtsA BcrAD_BadFG PF01869.20 KXT06775.1 - 0.03 13.8 2.4 0.03 13.8 0.2 2.1 3 0 0 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family ROK PF00480.20 KXT06775.1 - 0.046 13.2 1.2 0.1 12.0 0.2 2.0 2 0 0 2 2 2 0 ROK family Methyltransf_16 PF10294.9 KXT06776.1 - 1.2e-42 145.7 0.0 1.6e-42 145.2 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 KXT06776.1 - 0.16 11.5 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain DIOX_N PF14226.6 KXT06777.1 - 2.7e-19 70.1 0.1 7.6e-19 68.6 0.0 1.8 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXT06777.1 - 9.1e-11 42.2 0.0 1.6e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4638 PF15472.6 KXT06778.1 - 0.069 12.9 2.0 0.71 9.6 0.3 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4638) Peptidase_C48 PF02902.19 KXT06780.1 - 0.0011 18.8 0.0 0.0023 17.8 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Gpr1_Fun34_YaaH PF01184.19 KXT06781.1 - 1.5e-77 259.9 14.2 1.8e-77 259.6 14.2 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family HECT PF00632.25 KXT06784.1 - 5.2e-95 318.5 0.0 7.1e-95 318.0 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KXT06784.1 - 4.3e-33 113.1 18.8 1.2e-11 44.5 1.4 4.0 4 0 0 4 4 4 3 WW domain C2 PF00168.30 KXT06784.1 - 8.3e-20 71.0 0.0 1.9e-19 69.8 0.0 1.6 1 0 0 1 1 1 1 C2 domain Mucin PF01456.17 KXT06784.1 - 7.7 6.5 16.0 0.34 10.9 8.7 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein AAA PF00004.29 KXT06785.1 - 6.5e-17 62.2 0.0 1.3e-16 61.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXT06785.1 - 1.9e-06 28.2 0.6 0.0026 18.0 0.0 2.6 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.6 KXT06785.1 - 3.3e-06 27.6 0.6 4.8e-05 23.8 0.6 2.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KXT06785.1 - 0.0058 16.6 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KXT06785.1 - 0.016 15.0 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KXT06785.1 - 0.017 15.2 0.4 0.23 11.6 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 KXT06785.1 - 0.053 13.2 0.3 0.21 11.3 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KXT06785.1 - 0.076 13.0 0.0 0.26 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KXT06785.1 - 0.11 12.2 0.0 0.43 10.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KXT06785.1 - 0.13 12.0 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KXT06785.1 - 0.15 12.5 3.6 0.43 11.0 0.0 3.2 3 1 1 4 4 4 0 AAA domain tRNA-synt_1d PF00750.19 KXT06788.1 - 4.1e-94 315.4 9.5 6e-55 186.6 6.9 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.15 KXT06788.1 - 3.8e-23 81.9 2.8 2.7e-22 79.2 0.3 2.6 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 KXT06788.1 - 1.5e-08 35.1 0.1 4.6e-08 33.5 0.1 1.9 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain TraF PF13728.6 KXT06788.1 - 0.41 10.4 6.2 1 9.1 6.2 1.7 1 0 0 1 1 1 0 F plasmid transfer operon protein GST_C PF00043.25 KXT06789.1 - 4.6e-18 65.2 0.0 1.2e-17 63.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXT06789.1 - 6.9e-11 42.2 0.0 2.5e-10 40.4 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KXT06789.1 - 8.8e-08 32.3 0.0 5.7e-07 29.7 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KXT06789.1 - 2.8e-07 30.8 0.0 1e-06 29.0 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXT06789.1 - 5.6e-05 23.5 0.3 0.00016 22.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXT06789.1 - 0.0002 21.3 0.1 0.00052 20.0 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ATP-synt_C PF00137.21 KXT06790.1 - 2.6e-31 107.7 33.5 1.5e-18 66.9 12.9 2.1 2 0 0 2 2 2 2 ATP synthase subunit C ATP-synt_C PF00137.21 KXT06791.1 - 2.6e-31 107.7 33.5 1.5e-18 66.9 12.9 2.1 2 0 0 2 2 2 2 ATP synthase subunit C KOW PF00467.29 KXT06792.1 - 0.00035 20.4 1.4 0.00087 19.2 1.4 1.7 1 0 0 1 1 1 1 KOW motif DUF4208 PF13907.6 KXT06792.1 - 0.037 14.5 1.4 0.11 12.9 1.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) HisKA_2 PF07568.12 KXT06793.1 - 0.044 13.9 0.5 71 3.6 0.2 3.8 4 0 0 4 4 4 0 Histidine kinase HSP70 PF00012.20 KXT06794.1 - 0.0029 15.9 0.0 0.004 15.4 0.0 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KXT06794.1 - 0.016 14.0 0.0 0.027 13.3 0.0 1.2 1 0 0 1 1 1 0 MreB/Mbl protein TMEM154 PF15102.6 KXT06796.1 - 0.005 16.7 0.8 0.039 13.8 0.0 2.4 2 0 0 2 2 2 1 TMEM154 protein family Glycophorin_A PF01102.18 KXT06796.1 - 0.0098 16.1 2.2 0.01 16.1 0.2 2.1 2 0 0 2 2 2 1 Glycophorin A RIFIN PF02009.16 KXT06796.1 - 0.021 14.8 0.1 0.039 13.9 0.0 1.4 2 0 0 2 2 2 0 Rifin DUF2207 PF09972.9 KXT06796.1 - 0.075 11.8 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CHDCT2 PF08074.11 KXT06796.1 - 0.077 13.2 0.1 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain Podoplanin PF05808.11 KXT06796.1 - 6.3 6.9 12.7 0.17 12.0 5.3 2.0 2 1 0 2 2 2 0 Podoplanin Med22 PF06179.12 KXT06797.1 - 1.1e-10 41.6 5.2 1.9e-10 40.9 5.2 1.4 1 1 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex DUF2514 PF10721.9 KXT06797.1 - 0.014 15.4 2.3 0.019 15.0 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) CTNNB1_binding PF08347.11 KXT06798.1 - 0.035 14.3 1.3 0.035 14.3 1.3 1.7 2 0 0 2 2 2 0 N-terminal CTNNB1 binding Hs1pro-1_N PF07231.12 KXT06798.1 - 0.059 13.1 1.8 7.8 6.2 0.7 2.2 2 0 0 2 2 2 0 Hs1pro-1 N-terminus HK PF02110.15 KXT06799.1 - 4.2e-76 255.6 0.6 6.5e-76 255.0 0.6 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 KXT06799.1 - 5.4e-57 192.0 2.9 8.9e-57 191.3 2.9 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase Phos_pyr_kin PF08543.12 KXT06799.1 - 0.011 15.2 1.2 0.019 14.4 0.1 1.9 2 0 0 2 2 2 0 Phosphomethylpyrimidine kinase COesterase PF00135.28 KXT06800.1 - 1.8e-94 317.5 0.0 2.3e-94 317.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXT06800.1 - 0.0032 17.3 0.1 0.021 14.7 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXT06800.1 - 0.0037 16.8 0.3 0.0079 15.7 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family adh_short PF00106.25 KXT06801.1 - 2.3e-23 82.7 0.0 4.5e-23 81.7 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT06801.1 - 7.1e-16 58.5 0.0 1.2e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT06801.1 - 1.7e-07 31.3 0.0 3.2e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXT06801.1 - 0.00026 20.5 0.0 0.00035 20.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KXT06801.1 - 0.0098 15.2 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyco_transf_4 PF13439.6 KXT06801.1 - 0.15 12.1 0.0 0.34 10.9 0.0 1.7 1 1 0 1 1 1 0 Glycosyltransferase Family 4 Pyr_redox_3 PF13738.6 KXT06801.1 - 0.21 10.8 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Nse4_C PF08743.10 KXT06802.1 - 1.7e-32 111.5 0.0 9.7e-32 109.1 0.0 2.3 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 KXT06802.1 - 2.4e-13 50.0 1.3 2.4e-13 50.0 1.3 2.3 2 0 0 2 2 2 1 Binding domain of Nse4/EID3 to Nse3-MAGE ApoO PF09769.9 KXT06802.1 - 0.16 11.9 1.4 5.3 7.0 0.1 2.4 2 0 0 2 2 2 0 Apolipoprotein O ATHILA PF03078.15 KXT06802.1 - 0.26 10.0 3.0 0.53 9.0 3.0 1.4 1 0 0 1 1 1 0 ATHILA ORF-1 family GFA PF04828.14 KXT06803.1 - 7.7e-25 87.1 0.7 1e-24 86.7 0.7 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Fungal_trans PF04082.18 KXT06804.1 - 8.7e-50 169.2 0.5 1.4e-49 168.5 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 KXT06804.1 - 2.5e-48 164.1 0.0 6.5e-48 162.8 0.1 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT06804.1 - 2.8e-47 161.3 0.0 4.4e-47 160.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT06804.1 - 5.9e-09 36.1 0.1 1.2e-08 35.0 0.1 1.5 1 0 0 1 1 1 1 KR domain zf-C2H2 PF00096.26 KXT06804.1 - 8.6e-06 25.9 12.0 0.005 17.2 0.8 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type Epimerase PF01370.21 KXT06804.1 - 0.00082 18.9 0.1 0.0014 18.1 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ogr_Delta PF04606.12 KXT06804.1 - 0.0082 16.1 0.3 0.55 10.2 0.0 2.8 2 0 0 2 2 2 1 Ogr/Delta-like zinc finger zf-C2H2_4 PF13894.6 KXT06804.1 - 0.053 14.4 10.0 1.7 9.7 3.4 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger Glyco_transf_5 PF08323.11 KXT06804.1 - 0.11 12.2 0.0 0.98 9.1 0.0 2.3 2 1 1 3 3 3 0 Starch synthase catalytic domain FOXP-CC PF16159.5 KXT06804.1 - 0.67 10.6 4.9 7.8 7.2 0.9 2.7 1 1 1 2 2 2 0 FOXP coiled-coil domain Asn_synthase PF00733.21 KXT06805.1 - 8.7e-94 315.1 0.0 1.4e-54 186.1 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 KXT06805.1 - 4.7e-36 123.4 0.0 7.9e-36 122.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KXT06805.1 - 1.1e-25 90.4 0.0 2e-25 89.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KXT06805.1 - 0.00018 21.1 0.0 0.00031 20.3 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 KXT06805.1 - 0.0051 16.0 0.0 0.069 12.3 0.0 2.2 2 0 0 2 2 2 1 NAD synthase GCFC PF07842.12 KXT06806.1 - 1.8e-79 267.3 6.5 1.1e-78 264.7 7.5 1.8 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 KXT06806.1 - 3e-15 55.8 4.6 5.7e-15 54.9 4.6 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KXT06806.1 - 1.8e-08 34.3 1.9 5.6e-08 32.7 1.9 1.8 1 0 0 1 1 1 1 G-patch domain Cu-oxidase_3 PF07732.15 KXT06807.1 - 4.9e-37 126.6 3.7 1.5e-34 118.6 0.3 3.2 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KXT06807.1 - 1.6e-32 112.1 8.1 8.9e-26 90.3 0.3 3.3 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KXT06807.1 - 8.4e-15 55.2 0.0 8e-14 52.1 0.0 2.6 2 1 0 2 2 2 1 Multicopper oxidase zf-CCCH PF00642.24 KXT06808.1 - 1.5e-08 34.4 2.4 3.1e-08 33.3 2.4 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 KXT06808.1 - 2.3e-08 33.7 7.3 4.6e-08 32.8 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXT06808.1 - 3.5e-08 33.3 7.7 7e-08 32.4 7.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KXT06808.1 - 3.5e-08 33.1 10.5 6.9e-08 32.2 10.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KXT06808.1 - 1e-07 31.7 11.6 1.8e-07 30.9 11.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXT06808.1 - 5.7e-06 26.2 9.9 1.1e-05 25.3 9.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KXT06808.1 - 1.1e-05 25.6 7.3 2.2e-05 24.7 7.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf_CCCH_4 PF18345.1 KXT06808.1 - 2.1e-05 24.4 5.4 4.3e-05 23.4 5.4 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-C3HC4_4 PF15227.6 KXT06808.1 - 0.00027 21.0 9.1 0.00061 19.9 9.1 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KXT06808.1 - 0.00086 19.1 5.4 0.0017 18.2 5.4 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-CCCH_4 PF18044.1 KXT06808.1 - 0.00098 18.9 1.9 0.00098 18.9 1.9 2.1 2 0 0 2 2 1 1 CCCH-type zinc finger zf-Nse PF11789.8 KXT06808.1 - 0.022 14.6 4.8 0.041 13.7 4.8 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-CCCH_2 PF14608.6 KXT06808.1 - 0.052 14.0 2.5 0.13 12.8 2.5 1.7 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-RING_10 PF16685.5 KXT06808.1 - 0.33 11.1 9.8 0.047 13.8 5.8 1.7 2 0 0 2 2 1 0 zinc RING finger of MSL2 zf-rbx1 PF12678.7 KXT06808.1 - 0.37 11.1 4.8 0.82 10.0 4.8 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain Glyco_transf_90 PF05686.12 KXT06811.1 - 6.8e-15 54.9 3.8 2.1e-12 46.7 1.1 3.0 2 1 0 2 2 2 2 Glycosyl transferase family 90 PI3Ka PF00613.20 KXT06812.1 - 8.4e-52 175.3 0.3 1.3e-51 174.7 0.3 1.2 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 KXT06812.1 - 3.9e-42 144.8 0.0 9.5e-30 104.2 0.0 2.8 2 1 1 3 3 3 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 KXT06812.1 - 7.5e-31 106.9 0.0 1.3e-30 106.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF4135 PF13575.6 KXT06812.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) AMP-binding PF00501.28 KXT06813.1 - 2.1e-49 168.3 0.0 3.7e-49 167.5 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KXT06813.1 - 7.9e-27 94.0 1.6 4.1e-18 65.3 1.3 3.9 3 1 0 3 3 3 2 Condensation domain PP-binding PF00550.25 KXT06813.1 - 4.5e-10 39.7 0.0 2e-09 37.7 0.0 2.3 2 0 0 2 2 2 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KXT06813.1 - 0.0013 19.7 0.0 0.0042 18.0 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CoA_trans PF01144.23 KXT06814.1 - 1.3e-101 338.5 2.7 2.7e-60 203.4 0.5 2.1 2 0 0 2 2 2 2 Coenzyme A transferase Mal_decarbox_Al PF16957.5 KXT06814.1 - 0.0016 16.8 0.1 0.0025 16.2 0.1 1.2 1 0 0 1 1 1 1 Malonate decarboxylase, alpha subunit, transporter AcetylCoA_hyd_C PF13336.6 KXT06814.1 - 0.061 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain DUF1953 PF09196.10 KXT06814.1 - 0.092 12.6 0.0 1.1 9.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1953) TctB PF07331.11 KXT06815.1 - 0.013 15.8 2.0 0.013 15.8 2.0 1.6 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family F-box-like PF12937.7 KXT06816.1 - 0.015 15.2 0.8 0.038 13.9 0.4 1.9 2 0 0 2 2 2 0 F-box-like zf-RING_5 PF14634.6 KXT06818.1 - 1.4e-05 25.0 1.3 5e-05 23.2 1.4 1.9 1 1 0 1 1 1 1 zinc-RING finger domain Rx_N PF18052.1 KXT06818.1 - 0.0038 17.5 0.0 0.0061 16.8 0.0 1.3 1 0 0 1 1 1 1 Rx N-terminal domain Matrilin_ccoil PF10393.9 KXT06818.1 - 0.041 13.7 0.4 0.075 12.9 0.4 1.4 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Seryl_tRNA_N PF02403.22 KXT06818.1 - 0.13 12.4 1.0 0.2 11.9 1.0 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Macoilin PF09726.9 KXT06818.1 - 0.19 10.2 2.1 0.25 9.9 2.1 1.0 1 0 0 1 1 1 0 Macoilin family Prok-RING_4 PF14447.6 KXT06818.1 - 0.38 10.7 4.5 2.7 7.9 2.6 2.7 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KXT06818.1 - 0.42 11.0 3.2 2.3 8.6 3.2 2.2 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KXT06818.1 - 0.78 9.6 4.4 5.5 6.9 0.2 3.1 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXT06818.1 - 8 6.6 7.9 3.7 7.7 0.5 3.2 3 1 0 3 3 3 0 RING-type zinc-finger zf-RING_2 PF13639.6 KXT06818.1 - 9.5 6.6 8.0 1e+02 3.3 0.4 3.0 2 1 1 3 3 3 0 Ring finger domain DAO PF01266.24 KXT06819.1 - 6.2e-38 131.3 0.2 7.5e-38 131.0 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXT06819.1 - 0.002 18.1 0.1 0.013 15.5 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KXT06819.1 - 0.045 14.0 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXT06819.1 - 0.1 11.8 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase zf-C3H1 PF10650.9 KXT06820.1 - 2.4e-10 39.9 1.9 4.1e-10 39.2 1.9 1.4 1 0 0 1 1 1 1 Putative zinc-finger domain SOGA PF11365.8 KXT06820.1 - 8.5 7.6 9.3 57 4.9 0.1 3.8 3 0 0 3 3 3 0 Protein SOGA Voltage_CLC PF00654.20 KXT06821.1 - 6.3e-90 302.0 22.4 1.2e-89 301.1 22.4 1.4 1 0 0 1 1 1 1 Voltage gated chloride channel UCH PF00443.29 KXT06821.1 - 7e-62 209.2 0.2 1.2e-61 208.5 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KXT06821.1 - 6.8e-11 42.3 0.0 0.00021 21.0 0.0 3.2 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 KXT06821.1 - 3.3e-07 30.8 0.0 1.3e-06 28.9 0.0 2.1 1 0 0 1 1 1 1 DUSP domain ubiquitin PF00240.23 KXT06821.1 - 0.075 12.8 0.0 0.23 11.2 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin family 7tm_7 PF08395.12 KXT06821.1 - 0.88 8.7 3.1 0.54 9.4 0.3 1.9 2 0 0 2 2 2 0 7tm Chemosensory receptor PRIMA1 PF16101.5 KXT06821.1 - 6.3 6.9 9.4 17 5.5 9.4 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 AMPK1_CBM PF16561.5 KXT06822.1 - 2.3e-06 27.7 0.0 3.9e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase COesterase PF00135.28 KXT06823.1 - 3.9e-80 270.2 0.0 5.5e-80 269.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KXT06823.1 - 1.5e-06 28.2 0.2 1.1e-05 25.4 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KXT06823.1 - 5.3e-05 22.8 0.1 8.8e-05 22.1 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family GTP_EFTU PF00009.27 KXT06824.1 - 6.7e-54 182.4 0.0 1e-53 181.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 KXT06824.1 - 3.8e-24 84.6 0.0 1.1e-23 83.0 0.0 1.9 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_C PF00679.24 KXT06824.1 - 5.5e-15 55.2 0.0 5.8e-08 32.7 0.0 2.4 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KXT06824.1 - 5.7e-09 36.2 0.0 2.5e-08 34.2 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 KXT06824.1 - 2.5e-05 24.0 0.0 0.00022 21.0 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G, domain IV RF3_C PF16658.5 KXT06824.1 - 0.05 13.4 0.0 0.099 12.5 0.0 1.4 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain PAS PF00989.25 KXT06825.1 - 0.14 12.1 0.0 0.2 11.6 0.0 1.4 1 1 0 1 1 1 0 PAS fold Tweety PF04906.13 KXT06826.1 - 0.052 12.2 1.0 0.079 11.6 0.5 1.4 1 1 0 1 1 1 0 Tweety Fasciclin PF02469.22 KXT06828.1 - 7.9e-33 113.4 0.0 2e-19 70.1 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain COR PF16095.5 KXT06828.1 - 0.0097 15.7 0.0 0.33 10.8 0.0 2.1 2 0 0 2 2 2 1 C-terminal of Roc, COR, domain SFTA2 PF15210.6 KXT06828.1 - 0.077 12.9 1.6 0.31 11.0 0.2 2.5 3 0 0 3 3 3 0 Surfactant-associated protein 2 MRP-S25 PF13741.6 KXT06829.1 - 2.1e-49 168.2 16.7 7.1e-25 87.9 1.5 3.0 1 1 2 3 3 3 3 Mitochondrial ribosomal protein S25 Methyltransf_23 PF13489.6 KXT06830.1 - 2.4e-14 53.5 0.0 3.9e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXT06830.1 - 1.5e-10 41.1 0.0 4.7e-10 39.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXT06830.1 - 5.2e-10 39.8 0.0 1.9e-09 38.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXT06830.1 - 3.6e-08 34.0 0.0 1.1e-07 32.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXT06830.1 - 6.3e-08 33.2 0.0 3.1e-07 31.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KXT06830.1 - 0.0002 20.7 0.0 0.00049 19.4 0.0 1.6 2 0 0 2 2 2 1 O-methyltransferase domain MTS PF05175.14 KXT06830.1 - 0.0026 17.3 0.0 0.0045 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.12 KXT06830.1 - 0.011 14.8 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase RrnaAD PF00398.20 KXT06830.1 - 0.014 14.5 0.0 0.02 14.0 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_17 PF12692.7 KXT06830.1 - 0.026 14.5 0.0 0.042 13.9 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase CMAS PF02353.20 KXT06830.1 - 0.036 13.4 0.0 0.24 10.6 0.0 2.1 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Phage_min_cap2 PF06152.11 KXT06830.1 - 0.22 10.4 0.0 9 5.1 0.0 2.1 2 0 0 2 2 2 0 Phage minor capsid protein 2 Glyco_transf_90 PF05686.12 KXT06831.1 - 1.1e-28 100.2 2.2 1.1e-28 100.2 2.2 1.4 2 0 0 2 2 2 1 Glycosyl transferase family 90 PI-PLC-C1 PF16670.5 KXT06832.1 - 0.12 11.5 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 Phosphoinositide phospholipase C, Ca2+-dependent VraX PF17412.2 KXT06832.1 - 0.28 10.9 0.8 6.9 6.4 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function FAD_binding_3 PF01494.19 KXT06833.1 - 1.1e-82 278.1 0.0 5e-58 197.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Phe_hydrox_dim PF07976.12 KXT06833.1 - 5.3e-52 176.2 0.0 8.6e-52 175.5 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_2 PF00890.24 KXT06833.1 - 4.3e-05 22.8 0.2 7.8e-05 21.9 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXT06833.1 - 4.8e-05 22.7 0.2 0.00011 21.6 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXT06833.1 - 5.2e-05 22.1 0.1 8.3e-05 21.5 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 KXT06833.1 - 0.00014 21.2 0.1 0.00021 20.7 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXT06833.1 - 0.00027 21.1 0.1 0.002 18.3 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXT06833.1 - 0.00097 18.4 0.1 0.0043 16.3 0.0 1.9 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 KXT06833.1 - 0.0013 17.8 0.1 0.0024 17.0 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 KXT06833.1 - 0.015 14.4 0.1 0.024 13.7 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A DAO PF01266.24 KXT06833.1 - 0.017 14.7 0.0 0.038 13.6 0.0 1.7 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KXT06833.1 - 0.025 13.9 0.2 0.041 13.2 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 KXT06833.1 - 0.027 15.0 0.1 0.06 13.9 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KXT06833.1 - 0.044 13.1 0.0 0.071 12.4 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Zn_clus PF00172.18 KXT06834.1 - 1e-08 35.1 15.0 1e-08 35.1 15.0 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CENP-F_leu_zip PF10473.9 KXT06834.1 - 0.013 15.5 0.1 0.022 14.8 0.1 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4446 PF14584.6 KXT06834.1 - 0.019 15.0 0.2 0.042 13.8 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Viral_NABP PF05515.11 KXT06834.1 - 0.066 13.0 4.0 0.16 11.8 4.0 1.8 1 1 0 1 1 1 0 Viral nucleic acid binding NYD-SP28 PF14772.6 KXT06834.1 - 0.42 10.7 4.0 0.63 10.1 4.0 1.2 1 0 0 1 1 1 0 Sperm tail DZR PF12773.7 KXT06834.1 - 1 9.4 21.2 0.16 12.0 1.9 3.0 3 0 0 3 3 3 0 Double zinc ribbon Fungal_trans PF04082.18 KXT06835.1 - 3.4e-29 101.7 0.6 5.3e-29 101.1 0.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT06835.1 - 1.4e-09 37.9 8.6 3.6e-09 36.6 8.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AFG1_ATPase PF03969.16 KXT06836.1 - 3.7e-60 203.7 0.5 3.7e-26 91.9 0.0 5.2 3 2 1 5 5 5 5 AFG1-like ATPase AAA_16 PF13191.6 KXT06836.1 - 0.00017 22.0 0.3 0.0012 19.3 0.1 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KXT06836.1 - 0.0013 18.8 0.0 0.0029 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KXT06836.1 - 0.0027 18.0 0.0 0.0064 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KXT06836.1 - 0.025 14.3 0.0 0.076 12.8 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 KXT06836.1 - 0.025 15.0 0.0 0.071 13.5 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 KXT06836.1 - 0.04 13.3 0.0 0.076 12.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_7 PF12775.7 KXT06836.1 - 0.14 11.6 0.0 0.35 10.4 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region zf-C2H2_4 PF13894.6 KXT06837.1 - 5.8e-05 23.6 6.2 0.061 14.2 0.7 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KXT06837.1 - 0.00021 21.6 5.3 0.042 14.3 0.4 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type FAM76 PF16046.5 KXT06837.1 - 0.00085 18.8 6.4 0.0082 15.5 3.4 2.2 2 0 0 2 2 2 1 FAM76 protein SlyX PF04102.12 KXT06837.1 - 0.0057 17.3 6.3 0.62 10.7 0.3 2.9 2 0 0 2 2 2 2 SlyX FlxA PF14282.6 KXT06837.1 - 0.013 15.5 1.1 0.013 15.5 1.1 3.0 3 0 0 3 3 3 0 FlxA-like protein zf-Di19 PF05605.12 KXT06837.1 - 0.058 13.7 2.1 0.12 12.7 2.1 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Actin_micro PF17003.5 KXT06837.1 - 0.067 12.4 0.5 0.24 10.5 0.5 1.8 1 1 0 1 1 1 0 Putative actin-like family zf-H2C2_2 PF13465.6 KXT06837.1 - 0.077 13.5 5.0 0.07 13.6 2.2 2.3 2 0 0 2 2 2 0 Zinc-finger double domain DUF16 PF01519.16 KXT06837.1 - 0.08 13.4 3.9 2.1 8.9 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function DUF16 zf-C2H2_3rep PF18868.1 KXT06837.1 - 0.1 13.3 0.8 41 4.9 0.0 3.0 2 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf_UBZ PF18439.1 KXT06837.1 - 0.13 11.9 3.1 9.3 5.9 0.1 3.1 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger DUF641 PF04859.12 KXT06837.1 - 0.24 11.7 5.4 4 7.8 1.1 2.5 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) XhlA PF10779.9 KXT06837.1 - 0.26 11.5 2.1 3.3 8.0 0.2 3.1 3 0 0 3 3 3 0 Haemolysin XhlA MerR-DNA-bind PF09278.11 KXT06837.1 - 0.37 11.4 4.6 0.29 11.7 0.3 2.9 2 0 0 2 2 2 0 MerR, DNA binding TMF_DNA_bd PF12329.8 KXT06837.1 - 0.77 9.8 5.0 13 5.8 0.4 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Spectrin PF00435.21 KXT06837.1 - 1.3 9.6 9.2 5.4 7.6 0.5 3.7 4 1 0 4 4 4 0 Spectrin repeat DUF4140 PF13600.6 KXT06837.1 - 1.3 9.5 7.4 2.5 8.6 0.1 2.8 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) LPP PF04728.13 KXT06837.1 - 1.4 9.3 6.7 0.24 11.8 1.6 2.3 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Med21 PF11221.8 KXT06837.1 - 1.5 9.1 8.5 0.86 9.8 0.5 2.9 3 0 0 3 3 3 0 Subunit 21 of Mediator complex V-SNARE PF05008.15 KXT06837.1 - 2.4 8.6 6.8 1 9.8 0.6 2.9 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Csm1_N PF18504.1 KXT06837.1 - 5.9 7.3 7.0 27 5.2 0.6 2.9 3 0 0 3 3 3 0 Csm1 N-terminal domain CLZ PF16526.5 KXT06837.1 - 8.6 6.8 8.8 1.3 9.5 0.2 3.3 4 0 0 4 4 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Trypan_PARP PF05887.11 KXT06839.1 - 0.023 14.7 5.0 0.047 13.7 5.0 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) zf-H2C2_2 PF13465.6 KXT06840.1 - 6.2e-13 48.5 7.4 1.9e-07 31.2 0.2 4.0 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KXT06840.1 - 6.3e-13 48.4 12.4 2.5e-06 27.6 2.3 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXT06840.1 - 1.3e-08 34.9 10.2 0.00078 20.1 1.4 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KXT06840.1 - 3.6e-08 33.2 5.2 0.00049 20.0 0.3 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXT06840.1 - 2.7e-05 24.3 2.4 0.36 11.2 0.2 4.0 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KXT06840.1 - 0.00012 22.4 3.8 0.013 15.8 0.3 3.9 5 0 0 5 5 5 1 Zinc-finger of C2H2 type Zn_ribbon_recom PF13408.6 KXT06840.1 - 0.0075 16.8 0.8 0.02 15.4 0.8 1.7 1 0 0 1 1 1 1 Recombinase zinc beta ribbon domain zf-C2H2_11 PF16622.5 KXT06840.1 - 0.013 15.2 4.2 1.1 9.0 0.5 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-Di19 PF05605.12 KXT06840.1 - 0.066 13.5 1.4 0.2 12.0 1.4 1.8 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HE PF16278.5 KXT06840.1 - 0.31 11.5 2.0 9.5 6.8 0.3 2.6 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-BED PF02892.15 KXT06840.1 - 0.67 10.0 3.3 30 4.8 3.3 2.8 1 1 0 1 1 1 0 BED zinc finger PXPV PF12778.7 KXT06840.1 - 0.74 9.7 3.1 1.5 8.7 3.1 1.5 1 0 0 1 1 1 0 PXPV repeat (3 copies) LIM PF00412.22 KXT06840.1 - 0.99 9.7 3.2 25 5.2 0.1 2.4 1 1 1 2 2 2 0 LIM domain C5HCH PF17982.1 KXT06840.1 - 2.8 8.2 6.2 14 5.9 0.4 2.6 1 1 1 2 2 2 0 NSD Cys-His rich domain FYVE PF01363.21 KXT06840.1 - 3.1 8.0 5.3 6.3 7.0 5.3 1.5 1 0 0 1 1 1 0 FYVE zinc finger WD40 PF00400.32 KXT06841.1 - 3.8e-24 84.5 4.0 1.1e-06 29.3 0.0 6.3 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXT06841.1 - 6.2e-06 26.4 0.3 5.8e-05 23.3 0.1 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain 4HBT PF03061.22 KXT06841.1 - 0.036 14.4 0.3 8 6.9 0.0 2.5 2 0 0 2 2 2 0 Thioesterase superfamily SH3_9 PF14604.6 KXT06841.1 - 0.3 11.0 2.7 0.22 11.4 0.2 2.1 2 0 0 2 2 2 0 Variant SH3 domain TraL PF07178.11 KXT06842.1 - 0.16 12.5 0.0 0.28 11.7 0.0 1.4 1 0 0 1 1 1 0 TraL protein Lbh PF15317.6 KXT06844.1 - 0.079 13.8 0.1 0.26 12.2 0.1 1.8 1 0 0 1 1 1 0 Cardiac transcription factor regulator, Developmental protein Fungal_trans PF04082.18 KXT06846.1 - 5.5e-09 35.4 0.0 1.5e-08 34.0 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT06846.1 - 0.00013 22.0 5.2 0.00022 21.3 5.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXT06847.1 - 5.5e-09 35.4 0.0 1.5e-08 34.0 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT06847.1 - 0.00013 22.0 5.2 0.00022 21.3 5.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2OG-FeII_Oxy PF03171.20 KXT06848.1 - 0.0073 16.8 0.0 0.034 14.6 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Synapsin_N PF10581.9 KXT06848.1 - 0.13 12.3 0.1 0.3 11.1 0.1 1.7 1 0 0 1 1 1 0 Synapsin N-terminal DUF585 PF04522.12 KXT06850.1 - 0.0088 15.7 0.0 0.011 15.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF585) UspB PF10625.9 KXT06850.1 - 0.083 12.9 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Universal stress protein B (UspB) Aldo_ket_red PF00248.21 KXT06851.1 - 8.3e-70 235.3 0.0 9.9e-70 235.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Transp_cyt_pur PF02133.15 KXT06852.1 - 8e-76 255.6 38.9 9.4e-76 255.3 38.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF485 PF04341.12 KXT06852.1 - 1.4 8.9 7.5 1.4 8.9 2.0 3.3 2 1 0 2 2 2 0 Protein of unknown function, DUF485 adh_short_C2 PF13561.6 KXT06853.1 - 1.7e-38 132.5 0.0 2e-38 132.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXT06853.1 - 2.2e-32 112.1 0.0 3e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXT06853.1 - 9.3e-07 28.9 0.2 8e-06 25.9 0.2 2.2 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KXT06853.1 - 1.5e-06 27.9 0.0 8.7e-06 25.4 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KXT06853.1 - 1.4e-05 25.1 0.0 2.8e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KXT06853.1 - 0.00016 20.8 0.1 0.00023 20.3 0.1 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KXT06853.1 - 0.0048 16.3 0.0 0.0073 15.7 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase eIF3g PF12353.8 KXT06854.1 - 0.33 11.3 2.7 1.5 9.3 2.7 1.9 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G rRNA_proc-arch PF13234.6 KXT06855.1 - 1.1e-88 297.7 0.1 1.1e-88 297.7 0.1 2.2 3 0 0 3 3 3 1 rRNA-processing arch domain DSHCT PF08148.12 KXT06855.1 - 6e-58 195.1 1.8 1.8e-57 193.5 1.8 1.9 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 KXT06855.1 - 4.2e-19 69.0 0.0 1.9e-18 66.9 0.0 2.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXT06855.1 - 1.1e-06 29.0 0.0 7e-06 26.4 0.0 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXT06855.1 - 5.5e-06 26.5 0.0 2.7e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 KXT06855.1 - 0.0089 15.1 0.0 0.038 13.1 0.0 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF677 PF05055.12 KXT06855.1 - 0.02 13.8 0.2 0.058 12.3 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF677) AAA_22 PF13401.6 KXT06855.1 - 0.096 13.0 0.4 2.4 8.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain DUF5388 PF17363.2 KXT06855.1 - 0.16 12.2 0.7 1.4 9.2 0.2 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5388) DUF883 PF05957.13 KXT06855.1 - 9.9 6.8 13.2 1.4 9.6 0.4 4.0 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) NinG PF05766.12 KXT06856.1 - 0.08 12.9 1.3 0.14 12.1 1.3 1.4 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein RasGEF PF00617.19 KXT06857.1 - 2.6e-49 167.8 0.1 4.7e-49 167.0 0.1 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KXT06857.1 - 2.1e-14 53.6 0.0 6.6e-14 52.0 0.0 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.6 KXT06857.1 - 2.7e-05 24.0 0.0 6.7e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KXT06857.1 - 0.0027 17.3 0.0 0.0066 16.0 0.0 1.7 1 0 0 1 1 1 1 SH3 domain BAR_3 PF16746.5 KXT06857.1 - 0.038 13.7 0.1 4.1 7.0 0.0 2.6 2 0 0 2 2 2 0 BAR domain of APPL family DUF1279 PF06916.13 KXT06858.1 - 1.4e-19 70.4 0.0 3.5e-19 69.1 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) YCII PF03795.14 KXT06859.1 - 5.7e-08 33.1 0.0 8.1e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 YCII-related domain CTP_transf_like PF01467.26 KXT06860.1 - 4.3e-30 104.8 0.0 6.9e-30 104.1 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.12 KXT06860.1 - 0.042 13.7 0.0 0.074 12.9 0.0 1.4 1 0 0 1 1 1 0 FAD synthetase 2OG-FeII_Oxy_2 PF13532.6 KXT06861.1 - 3.5e-12 46.9 0.0 7.7e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-RanBP PF00641.18 KXT06861.1 - 0.62 9.4 5.5 0.058 12.7 0.5 1.9 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others MFS_1 PF07690.16 KXT06862.1 - 0.046 12.6 14.6 0.49 9.3 14.6 2.0 1 1 0 1 1 1 0 Major Facilitator Superfamily DUF2304 PF10066.9 KXT06862.1 - 0.26 11.5 2.0 4.3 7.6 0.4 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) LIP PF03583.14 KXT06863.1 - 5.6e-55 186.7 0.2 7.4e-55 186.3 0.2 1.1 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.21 KXT06863.1 - 0.011 15.3 0.1 0.37 10.2 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Gate PF07670.14 KXT06863.1 - 0.061 13.6 0.2 4.3 7.7 0.1 2.6 2 0 0 2 2 2 0 Nucleoside recognition NAGLU_N PF12971.7 KXT06865.1 - 0.13 12.1 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain NAGLU_N PF12971.7 KXT06866.1 - 0.13 12.1 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain NAGLU_N PF12971.7 KXT06868.1 - 0.13 12.1 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain PP2C PF00481.21 KXT06869.1 - 4.8e-83 278.7 0.0 6.1e-83 278.4 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KXT06869.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.5 1 1 0 1 1 1 0 Protein phosphatase 2C PP2C PF00481.21 KXT06870.1 - 1.1e-82 277.6 0.0 1.6e-82 277.0 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 KXT06871.1 - 4.7e-81 272.2 0.0 7e-81 271.6 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C NAGLU_N PF12971.7 KXT06872.1 - 0.13 12.1 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain PP2C PF00481.21 KXT06873.1 - 4.8e-83 278.7 0.0 6.1e-83 278.4 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KXT06873.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.5 1 1 0 1 1 1 0 Protein phosphatase 2C PP2C PF00481.21 KXT06875.1 - 5e-83 278.7 0.0 6.5e-83 278.3 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KXT06875.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.5 1 1 0 1 1 1 0 Protein phosphatase 2C NAGLU_N PF12971.7 KXT06876.1 - 0.13 12.1 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain Tcp11 PF05794.13 KXT06877.1 - 4.7e-96 322.6 4.2 7.2e-96 322.0 4.2 1.2 1 0 0 1 1 1 1 T-complex protein 11 Glyco_hydro_79C PF16862.5 KXT06878.1 - 6.8e-22 78.3 0.1 1.6e-21 77.1 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain PUF PF00806.19 KXT06879.1 - 1.7e-28 96.6 0.0 2.9e-06 26.6 0.0 6.2 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.22 KXT06879.1 - 1.6e-12 47.1 0.0 3.6e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 KXT06879.1 - 0.034 13.8 0.0 0.074 12.7 0.0 1.5 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated PUF PF00806.19 KXT06880.1 - 1.9e-27 93.3 0.0 4.6e-06 26.0 0.0 6.1 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat Glyco_hydro_79C PF16862.5 KXT06880.1 - 2.3e-21 76.6 0.1 7.6e-21 74.9 0.1 2.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain RRM_1 PF00076.22 KXT06880.1 - 7.2e-13 48.2 0.0 5.7e-12 45.3 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 KXT06880.1 - 0.051 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated MFS_1 PF07690.16 KXT06881.1 - 4.1e-33 114.8 28.0 1.3e-28 99.9 17.3 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 KXT06881.1 - 7.8e-10 38.2 0.5 7.8e-10 38.2 0.5 3.1 4 1 0 4 4 4 1 Sugar (and other) transporter DUF21 PF01595.20 KXT06881.1 - 0.058 13.1 4.6 2.9 7.6 0.9 2.7 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain DUF4131 PF13567.6 KXT06881.1 - 7.4 6.2 9.3 4.2 7.0 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) Aminotran_4 PF01063.19 KXT06883.1 - 6.8e-23 81.7 0.0 1.3e-22 80.8 0.0 1.5 1 0 0 1 1 1 1 Amino-transferase class IV adh_short_C2 PF13561.6 KXT06884.1 - 1.3e-43 149.2 2.9 1.6e-43 149.0 2.9 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXT06884.1 - 2.4e-39 134.8 1.5 3.1e-39 134.5 1.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXT06884.1 - 1.2e-06 28.6 0.1 1.9e-06 27.9 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXT06884.1 - 2.4e-05 23.9 0.4 4.6e-05 23.0 0.4 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ThiF PF00899.21 KXT06884.1 - 0.087 12.2 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 ThiF family BTB PF00651.31 KXT06886.1 - 0.081 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain SKG6 PF08693.10 KXT06890.1 - 1.3e-08 34.1 6.8 3.5e-08 32.7 6.8 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.6 KXT06890.1 - 5.2e-05 23.2 0.1 5.2e-05 23.2 0.1 3.2 1 1 1 2 2 1 1 TMEM154 protein family CD34_antigen PF06365.12 KXT06890.1 - 0.0011 18.6 0.0 0.0026 17.4 0.0 1.5 1 0 0 1 1 1 1 CD34/Podocalyxin family PAP_PilO PF06864.12 KXT06890.1 - 0.0065 15.4 0.1 0.013 14.4 0.1 1.4 1 0 0 1 1 1 1 Pilin accessory protein (PilO) DUF4448 PF14610.6 KXT06890.1 - 0.0076 16.0 0.5 0.019 14.8 0.4 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) Amnionless PF14828.6 KXT06890.1 - 0.0088 14.9 0.1 0.013 14.4 0.1 1.1 1 0 0 1 1 1 1 Amnionless CcmD PF04995.14 KXT06890.1 - 0.026 14.6 1.3 0.057 13.5 1.3 1.6 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Rax2 PF12768.7 KXT06890.1 - 0.067 12.6 5.0 0.21 11.0 5.0 1.8 1 1 0 1 1 1 0 Cortical protein marker for cell polarity DUF3619 PF12279.8 KXT06890.1 - 0.071 13.4 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) EphA2_TM PF14575.6 KXT06890.1 - 0.092 13.6 0.0 0.2 12.5 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2500 PF10694.9 KXT06890.1 - 0.096 13.2 0.2 0.92 10.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2500) MASE3 PF17159.4 KXT06890.1 - 0.099 12.2 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Membrane-associated sensor domain DUF4381 PF14316.6 KXT06890.1 - 0.2 11.9 0.0 0.31 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF3377 PF11857.8 KXT06890.1 - 0.27 11.2 0.7 0.6 10.1 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Hamartin PF04388.12 KXT06890.1 - 0.67 8.6 14.4 0.7 8.5 14.4 1.2 1 0 0 1 1 1 0 Hamartin protein DUF4330 PF14221.6 KXT06890.1 - 1.2 9.4 4.3 2.2 8.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4330) Stevor PF17410.2 KXT06890.1 - 2.4 7.6 4.9 0.78 9.2 0.0 2.0 1 1 1 2 2 2 0 Subtelomeric Variable Open Reading frame Porin_3 PF01459.22 KXT06891.1 - 4.3e-52 177.2 8.1 3.3e-45 154.6 3.2 2.1 2 0 0 2 2 2 2 Eukaryotic porin P_proprotein PF01483.20 KXT06891.1 - 0.041 13.9 0.3 0.1 12.6 0.0 1.8 2 0 0 2 2 2 0 Proprotein convertase P-domain OMP_b-brl PF13505.6 KXT06891.1 - 0.06 13.5 6.6 0.034 14.3 3.4 2.1 2 0 0 2 2 2 0 Outer membrane protein beta-barrel domain SKG6 PF08693.10 KXT06892.1 - 3.4e-08 32.7 6.8 3.4e-08 32.7 6.8 1.8 2 0 0 2 2 2 1 Transmembrane alpha-helix domain CD34_antigen PF06365.12 KXT06892.1 - 0.0011 18.6 0.0 0.0025 17.4 0.0 1.6 1 0 0 1 1 1 1 CD34/Podocalyxin family PAP_PilO PF06864.12 KXT06892.1 - 0.0063 15.4 0.1 0.012 14.4 0.1 1.4 1 0 0 1 1 1 1 Pilin accessory protein (PilO) DUF4448 PF14610.6 KXT06892.1 - 0.0076 16.0 0.6 0.017 14.9 0.4 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) Amnionless PF14828.6 KXT06892.1 - 0.0086 15.0 0.1 0.012 14.5 0.1 1.1 1 0 0 1 1 1 1 Amnionless CcmD PF04995.14 KXT06892.1 - 0.023 14.8 1.2 0.05 13.7 1.2 1.6 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF3619 PF12279.8 KXT06892.1 - 0.068 13.5 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) Rax2 PF12768.7 KXT06892.1 - 0.069 12.6 3.6 0.19 11.1 3.6 1.8 1 1 0 1 1 1 0 Cortical protein marker for cell polarity TMEM154 PF15102.6 KXT06892.1 - 0.075 12.9 22.1 2.3e+02 1.7 22.0 3.2 1 1 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.6 KXT06892.1 - 0.089 13.7 0.0 0.2 12.6 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2500 PF10694.9 KXT06892.1 - 0.092 13.3 0.2 0.9 10.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2500) MASE3 PF17159.4 KXT06892.1 - 0.1 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Membrane-associated sensor domain DUF4381 PF14316.6 KXT06892.1 - 0.19 11.9 0.0 0.3 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF3377 PF11857.8 KXT06892.1 - 0.26 11.2 0.7 0.58 10.1 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Hamartin PF04388.12 KXT06892.1 - 0.92 8.1 14.5 0.96 8.0 14.5 1.2 1 0 0 1 1 1 0 Hamartin protein DUF4330 PF14221.6 KXT06892.1 - 1.1 9.4 4.4 2.2 8.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4330) Stevor PF17410.2 KXT06892.1 - 1.5 8.3 3.6 0.75 9.3 0.0 1.9 1 1 1 2 2 2 0 Subtelomeric Variable Open Reading frame SKG6 PF08693.10 KXT06893.1 - 3.4e-08 32.7 6.8 3.4e-08 32.7 6.8 1.8 2 0 0 2 2 2 1 Transmembrane alpha-helix domain CD34_antigen PF06365.12 KXT06893.1 - 0.0011 18.6 0.0 0.0025 17.4 0.0 1.6 1 0 0 1 1 1 1 CD34/Podocalyxin family PAP_PilO PF06864.12 KXT06893.1 - 0.0063 15.4 0.1 0.012 14.4 0.1 1.4 1 0 0 1 1 1 1 Pilin accessory protein (PilO) DUF4448 PF14610.6 KXT06893.1 - 0.0076 16.0 0.6 0.017 14.9 0.4 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) Amnionless PF14828.6 KXT06893.1 - 0.0086 15.0 0.1 0.012 14.5 0.1 1.1 1 0 0 1 1 1 1 Amnionless CcmD PF04995.14 KXT06893.1 - 0.023 14.8 1.2 0.05 13.7 1.2 1.6 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF3619 PF12279.8 KXT06893.1 - 0.068 13.5 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) Rax2 PF12768.7 KXT06893.1 - 0.069 12.6 3.6 0.19 11.1 3.6 1.8 1 1 0 1 1 1 0 Cortical protein marker for cell polarity TMEM154 PF15102.6 KXT06893.1 - 0.075 12.9 22.1 2.3e+02 1.7 22.0 3.2 1 1 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.6 KXT06893.1 - 0.089 13.7 0.0 0.2 12.6 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2500 PF10694.9 KXT06893.1 - 0.092 13.3 0.2 0.9 10.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2500) MASE3 PF17159.4 KXT06893.1 - 0.1 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Membrane-associated sensor domain DUF4381 PF14316.6 KXT06893.1 - 0.19 11.9 0.0 0.3 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF3377 PF11857.8 KXT06893.1 - 0.26 11.2 0.7 0.58 10.1 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Hamartin PF04388.12 KXT06893.1 - 0.92 8.1 14.5 0.96 8.0 14.5 1.2 1 0 0 1 1 1 0 Hamartin protein DUF4330 PF14221.6 KXT06893.1 - 1.1 9.4 4.4 2.2 8.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4330) Stevor PF17410.2 KXT06893.1 - 1.5 8.3 3.6 0.75 9.3 0.0 1.9 1 1 1 2 2 2 0 Subtelomeric Variable Open Reading frame Porin_3 PF01459.22 KXT06894.1 - 4.3e-52 177.2 8.1 3.3e-45 154.6 3.2 2.1 2 0 0 2 2 2 2 Eukaryotic porin P_proprotein PF01483.20 KXT06894.1 - 0.041 13.9 0.3 0.1 12.6 0.0 1.8 2 0 0 2 2 2 0 Proprotein convertase P-domain OMP_b-brl PF13505.6 KXT06894.1 - 0.06 13.5 6.6 0.034 14.3 3.4 2.1 2 0 0 2 2 2 0 Outer membrane protein beta-barrel domain SKG6 PF08693.10 KXT06895.1 - 3.4e-08 32.7 6.8 3.4e-08 32.7 6.8 1.8 2 0 0 2 2 2 1 Transmembrane alpha-helix domain CD34_antigen PF06365.12 KXT06895.1 - 0.0011 18.6 0.0 0.0025 17.4 0.0 1.6 1 0 0 1 1 1 1 CD34/Podocalyxin family PAP_PilO PF06864.12 KXT06895.1 - 0.0063 15.4 0.1 0.012 14.4 0.1 1.4 1 0 0 1 1 1 1 Pilin accessory protein (PilO) DUF4448 PF14610.6 KXT06895.1 - 0.0076 16.0 0.6 0.017 14.9 0.4 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) Amnionless PF14828.6 KXT06895.1 - 0.0086 15.0 0.1 0.012 14.5 0.1 1.1 1 0 0 1 1 1 1 Amnionless CcmD PF04995.14 KXT06895.1 - 0.023 14.8 1.2 0.05 13.7 1.2 1.6 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF3619 PF12279.8 KXT06895.1 - 0.068 13.5 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) Rax2 PF12768.7 KXT06895.1 - 0.069 12.6 3.6 0.19 11.1 3.6 1.8 1 1 0 1 1 1 0 Cortical protein marker for cell polarity TMEM154 PF15102.6 KXT06895.1 - 0.075 12.9 22.1 2.3e+02 1.7 22.0 3.2 1 1 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.6 KXT06895.1 - 0.089 13.7 0.0 0.2 12.6 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2500 PF10694.9 KXT06895.1 - 0.092 13.3 0.2 0.9 10.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2500) MASE3 PF17159.4 KXT06895.1 - 0.1 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Membrane-associated sensor domain DUF4381 PF14316.6 KXT06895.1 - 0.19 11.9 0.0 0.3 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF3377 PF11857.8 KXT06895.1 - 0.26 11.2 0.7 0.58 10.1 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Hamartin PF04388.12 KXT06895.1 - 0.92 8.1 14.5 0.96 8.0 14.5 1.2 1 0 0 1 1 1 0 Hamartin protein DUF4330 PF14221.6 KXT06895.1 - 1.1 9.4 4.4 2.2 8.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4330) Stevor PF17410.2 KXT06895.1 - 1.5 8.3 3.6 0.75 9.3 0.0 1.9 1 1 1 2 2 2 0 Subtelomeric Variable Open Reading frame Ank_2 PF12796.7 KXT06896.1 - 7.8e-23 80.9 0.0 1.8e-11 44.5 0.0 3.5 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXT06896.1 - 2.1e-18 66.4 0.2 3.6e-07 30.6 0.1 4.2 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXT06896.1 - 2.1e-12 46.0 1.5 0.0047 17.3 0.0 5.9 6 0 0 6 6 6 3 Ankyrin repeat GDPD PF03009.17 KXT06896.1 - 4.1e-12 46.4 0.0 1.4e-11 44.6 0.0 1.8 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family SPX PF03105.19 KXT06896.1 - 6.9e-09 36.1 0.9 6.9e-09 36.1 0.9 5.0 1 1 1 2 2 2 1 SPX domain Ank_5 PF13857.6 KXT06896.1 - 3.2e-07 30.5 0.1 0.087 13.2 0.0 4.2 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 KXT06896.1 - 9.2e-06 25.9 0.1 0.011 16.2 0.0 4.3 4 0 0 4 4 4 1 Ankyrin repeat Med5 PF08689.10 KXT06897.1 - 3.9e-67 227.0 0.0 1.8e-65 221.5 0.0 2.9 1 1 0 1 1 1 1 Mediator complex subunit Med5 Taxilin PF09728.9 KXT06898.1 - 0.0038 16.5 0.3 0.0071 15.6 0.2 1.4 1 1 0 1 1 1 1 Myosin-like coiled-coil protein CDC37_N PF03234.14 KXT06900.1 - 0.15 12.9 0.3 0.15 12.9 0.3 2.5 1 1 2 3 3 3 0 Cdc37 N terminal kinase binding Suppressor_APC PF11414.8 KXT06900.1 - 0.61 10.2 6.5 5.3 7.2 1.5 3.5 3 0 0 3 3 3 0 Adenomatous polyposis coli tumour suppressor protein CutC PF03932.14 KXT06901.1 - 1.1e-56 191.5 0.0 1.3e-56 191.3 0.0 1.1 1 0 0 1 1 1 1 CutC family Alba PF01918.21 KXT06902.1 - 7.4e-08 32.1 0.5 1.2e-07 31.4 0.5 1.3 1 0 0 1 1 1 1 Alba Tyrosinase PF00264.20 KXT06903.1 - 7.7e-37 127.7 1.3 1.2e-36 127.1 1.3 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase FAD_binding_4 PF01565.23 KXT06904.1 - 1.1e-23 83.5 0.2 1.9e-23 82.7 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain PAS_9 PF13426.7 KXT06905.1 - 4.4e-12 46.2 0.0 4.7e-11 42.9 0.0 2.4 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 KXT06905.1 - 1.8e-05 24.7 0.0 6.9e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 PAS fold CRAL_TRIO_2 PF13716.6 KXT06906.1 - 2.9e-30 105.2 0.0 4.6e-30 104.6 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.27 KXT06906.1 - 9e-19 67.8 0.0 2.2e-18 66.5 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO PF00650.20 KXT06906.1 - 8.7e-05 22.3 0.0 0.00043 20.0 0.0 1.9 2 0 0 2 2 2 1 CRAL/TRIO domain Glyco_transf_22 PF03901.17 KXT06907.1 - 3.7e-75 253.7 19.5 4.5e-75 253.5 19.5 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PMT_2 PF13231.6 KXT06907.1 - 0.00066 19.9 8.5 0.00066 19.9 8.5 2.5 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Ima1_N PF09779.9 KXT06908.1 - 1.3e-32 113.5 6.0 1.3e-32 113.5 6.0 1.7 2 0 0 2 2 2 1 Ima1 N-terminal domain OppC_N PF12911.7 KXT06908.1 - 0.032 14.2 0.8 0.33 11.0 0.0 2.9 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C zinc_ribbon_10 PF10058.9 KXT06908.1 - 0.25 11.1 3.0 3.2 7.5 0.0 2.7 2 1 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein HypA PF01155.19 KXT06908.1 - 0.39 10.8 2.3 0.51 10.4 0.4 2.0 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 KXT06908.1 - 3.3 7.8 6.2 7.7 6.6 0.3 2.4 2 0 0 2 2 2 0 Double zinc ribbon BTB PF00651.31 KXT06910.1 - 1.3e-06 28.6 0.0 2.3e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain UQ_con PF00179.26 KXT06911.1 - 1.5e-46 157.5 0.0 2.5e-46 156.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme ABC1 PF03109.16 KXT06911.1 - 1.5e-31 109.0 0.0 2.4e-31 108.4 0.0 1.3 1 0 0 1 1 1 1 ABC1 family Prok-E2_B PF14461.6 KXT06911.1 - 0.0031 17.2 0.0 0.006 16.3 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B Aa_trans PF01490.18 KXT06912.1 - 2.5e-47 161.5 23.2 2.5e-47 161.5 23.2 1.6 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein AA_permease PF00324.21 KXT06912.1 - 1.6e-06 27.0 24.1 1.6e-06 27.0 24.1 1.9 3 0 0 3 3 3 1 Amino acid permease Spore_permease PF03845.13 KXT06912.1 - 0.0011 17.9 15.8 0.0011 17.9 15.8 1.9 3 0 0 3 3 3 1 Spore germination protein Trp_Tyr_perm PF03222.13 KXT06912.1 - 0.0028 16.8 18.7 0.0053 15.8 18.8 1.6 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family COX6A PF02046.15 KXT06912.1 - 0.2 12.1 0.0 1.7 9.2 0.0 2.4 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIa Glyco_hydro_92 PF07971.12 KXT06913.1 - 2.6e-145 484.9 0.1 3.4e-145 484.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KXT06913.1 - 9.5e-64 215.5 0.3 1.7e-63 214.7 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain DAO PF01266.24 KXT06914.1 - 1.8e-49 169.2 0.0 3.2e-49 168.4 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 KXT06914.1 - 7.7e-44 148.6 0.1 1.6e-43 147.6 0.1 1.6 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 KXT06914.1 - 1.7e-09 37.3 0.0 3e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KXT06914.1 - 8.1e-05 22.0 0.1 0.00057 19.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KXT06914.1 - 0.00014 21.3 0.0 0.0016 17.9 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXT06914.1 - 0.026 14.8 0.2 0.072 13.3 0.2 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 KXT06914.1 - 0.028 14.3 0.1 0.053 13.4 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 KXT06914.1 - 0.056 12.5 0.3 0.45 9.5 0.1 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KXT06914.1 - 0.074 12.3 0.1 0.21 10.8 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXT06914.1 - 0.1 13.2 0.1 0.35 11.5 0.1 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXT06914.1 - 0.17 10.6 0.9 0.27 9.9 0.4 1.5 2 0 0 2 2 2 0 HI0933-like protein Vps5 PF09325.10 KXT06916.1 - 1.1e-13 51.3 5.5 1.1e-13 51.3 5.5 1.7 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.24 KXT06916.1 - 2.3e-10 40.4 0.0 4.8e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 PX domain NST1 PF13945.6 KXT06916.1 - 3.5 7.7 17.9 0.3 11.2 3.3 2.4 2 0 0 2 2 2 0 Salt tolerance down-regulator Acetyltransf_8 PF13523.6 KXT06917.1 - 1.2e-50 170.9 0.1 1.9e-50 170.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KXT06917.1 - 0.0087 16.7 0.0 0.017 15.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FAD-oxidase_C PF02913.19 KXT06918.1 - 4.1e-53 180.6 0.3 9.9e-53 179.3 0.1 1.7 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KXT06918.1 - 4.5e-40 136.6 0.0 7.5e-40 135.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain SepSecS PF05889.13 KXT06918.1 - 0.01 14.6 0.0 0.019 13.7 0.0 1.3 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS ANF_receptor PF01094.28 KXT06918.1 - 0.071 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Receptor family ligand binding region FAD-oxidase_C PF02913.19 KXT06919.1 - 4.1e-53 180.6 0.3 9.9e-53 179.3 0.1 1.7 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KXT06919.1 - 4.5e-40 136.6 0.0 7.5e-40 135.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain SepSecS PF05889.13 KXT06919.1 - 0.01 14.6 0.0 0.019 13.7 0.0 1.3 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS ANF_receptor PF01094.28 KXT06919.1 - 0.071 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Receptor family ligand binding region NAD_binding_10 PF13460.6 KXT06922.1 - 4.5e-05 23.4 0.0 0.00024 21.1 0.0 2.1 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXT06922.1 - 0.0024 17.4 0.0 0.0048 16.4 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KXT06922.1 - 0.003 16.6 0.0 0.0048 15.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KXT06922.1 - 0.009 15.2 0.0 0.094 11.9 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.17 KXT06922.1 - 0.061 12.4 0.0 0.22 10.6 0.0 1.9 2 1 0 2 2 2 0 RmlD substrate binding domain Macoilin PF09726.9 KXT06923.1 - 6.9 5.1 9.0 7.6 5.0 9.0 1.1 1 0 0 1 1 1 0 Macoilin family RIFIN PF02009.16 KXT06923.1 - 8.5 6.2 6.0 11 5.9 6.0 1.1 1 0 0 1 1 1 0 Rifin Aldo_ket_red PF00248.21 KXT06925.1 - 1.4e-47 162.3 0.0 5.9e-47 160.3 0.0 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 KXT06926.1 - 1.4e-47 162.3 0.0 5.9e-47 160.3 0.0 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family APG17 PF04108.12 KXT06927.1 - 1.4e-112 376.7 8.1 1.6e-112 376.5 8.1 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 DUF615 PF04751.14 KXT06927.1 - 0.00036 20.5 1.5 0.021 14.8 0.4 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF615) RasGAP_C PF03836.15 KXT06927.1 - 0.0013 18.9 3.4 2.5 8.2 0.4 4.0 2 2 0 3 3 3 1 RasGAP C-terminus DUF5610 PF18433.1 KXT06927.1 - 0.013 16.0 0.1 0.046 14.2 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5610) NAP PF00956.18 KXT06927.1 - 0.07 12.3 0.2 0.17 11.0 0.0 1.8 2 0 0 2 2 2 0 Nucleosome assembly protein (NAP) OmpH PF03938.14 KXT06927.1 - 0.1 12.9 5.7 5 7.5 0.1 4.2 4 2 0 4 4 4 0 Outer membrane protein (OmpH-like) SHE3 PF17078.5 KXT06927.1 - 0.13 12.0 3.6 2.7 7.6 0.4 3.0 2 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 Prominin PF05478.11 KXT06927.1 - 0.23 9.4 3.4 0.1 10.5 0.5 1.8 2 1 0 2 2 2 0 Prominin SVIP PF15811.5 KXT06927.1 - 0.28 11.7 2.4 0.81 10.2 2.4 1.8 1 0 0 1 1 1 0 Small VCP/p97-interacting protein Baculo_PEP_C PF04513.12 KXT06927.1 - 0.64 10.1 4.4 7.5 6.6 0.8 3.4 4 1 1 5 5 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus AATF-Che1 PF13339.6 KXT06927.1 - 0.87 10.3 5.6 23 5.6 2.6 3.6 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor DUF2408 PF10303.9 KXT06927.1 - 1.1 9.8 6.3 13 6.3 0.1 3.5 1 1 2 4 4 4 0 Protein of unknown function (DUF2408) CdvA PF18822.1 KXT06927.1 - 2.1 8.2 13.8 6 6.7 0.6 4.4 5 0 0 5 5 5 0 CdvA-like coiled-coil domain DUF5082 PF16888.5 KXT06927.1 - 2.3 8.5 5.5 19 5.5 0.6 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF5082) Syntaxin-6_N PF09177.11 KXT06927.1 - 3.3 8.3 11.6 1.4 9.5 1.0 4.4 2 2 2 4 4 4 0 Syntaxin 6, N-terminal ZapB PF06005.12 KXT06927.1 - 3.5 8.1 8.9 1.6 9.3 0.5 3.8 3 1 0 3 3 3 0 Cell division protein ZapB WXG100 PF06013.12 KXT06927.1 - 4.1 7.7 10.1 34 4.8 0.2 5.4 6 1 0 6 6 5 0 Proteins of 100 residues with WXG Seryl_tRNA_N PF02403.22 KXT06927.1 - 5.7 7.2 12.2 0.74 10.1 1.0 4.0 4 1 0 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Pex19 PF04614.12 KXT06928.1 - 2.6e-69 233.7 20.6 2.6e-69 233.7 20.6 1.8 2 0 0 2 2 2 1 Pex19 protein family PP2C_C PF07830.13 KXT06928.1 - 0.012 16.0 8.6 0.091 13.2 0.0 3.8 4 1 1 5 5 5 0 Protein serine/threonine phosphatase 2C, C-terminal domain DUF445 PF04286.12 KXT06928.1 - 0.063 13.1 3.9 2.2 8.0 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF445) Cadherin_C PF01049.17 KXT06928.1 - 0.089 13.1 5.4 0.046 14.1 2.2 2.0 1 1 1 2 2 2 0 Cadherin cytoplasmic region TetR_C_28 PF17937.1 KXT06928.1 - 0.2 12.1 4.9 0.64 10.5 0.6 3.2 3 1 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain TIP120 PF08623.10 KXT06928.1 - 0.45 10.3 3.1 0.83 9.4 0.2 2.1 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) TetR_C_23 PF17931.1 KXT06928.1 - 0.55 10.4 2.4 20 5.3 0.0 3.2 2 2 2 4 4 4 0 Tetracyclin repressor-like, C-terminal domain PHA_synth_III_E PF09712.10 KXT06928.1 - 1 8.4 13.5 3.1 6.8 1.0 2.2 1 1 1 2 2 2 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) Ndc1_Nup PF09531.10 KXT06928.1 - 1.7 7.2 4.0 2.2 6.9 4.0 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup GET2 PF08690.10 KXT06928.1 - 2.4 7.7 24.4 3.1 7.4 3.1 2.3 1 1 1 2 2 2 0 GET complex subunit GET2 TORC_N PF12884.7 KXT06928.1 - 2.6 8.9 8.1 0.37 11.6 0.9 3.1 2 1 1 3 3 3 0 Transducer of regulated CREB activity, N terminus FliE PF02049.18 KXT06928.1 - 6.5 7.0 16.1 2.5 8.3 3.5 4.5 4 1 1 5 5 5 0 Flagellar hook-basal body complex protein FliE Pkinase PF00069.25 KXT06933.1 - 5e-25 88.3 0.0 7.3e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT06933.1 - 3.4e-07 29.8 0.0 0.00017 20.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXT06933.1 - 0.006 15.4 0.0 0.0085 14.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KXT06933.1 - 0.014 15.3 6.8 0.024 14.6 0.9 2.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KXT06933.1 - 1.5 8.2 4.8 0.25 10.7 0.2 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KXT06934.1 - 2.7e-72 243.3 0.0 6.3e-72 242.1 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT06934.1 - 6.6e-51 173.1 0.0 1.1e-50 172.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KXT06934.1 - 0.0027 16.6 0.0 0.0052 15.6 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Med15_fungi PF05397.12 KXT06934.1 - 0.021 15.1 0.3 0.056 13.7 0.3 1.7 1 0 0 1 1 1 0 Mediator complex subunit 15 Kinase-like PF14531.6 KXT06934.1 - 0.06 12.7 0.0 0.28 10.5 0.0 1.9 2 0 0 2 2 2 0 Kinase-like CDC14 PF08045.11 KXT06934.1 - 0.085 11.9 0.7 1.4 7.9 0.1 2.4 2 0 0 2 2 2 0 Cell division control protein 14, SIN component Seadorna_VP7 PF07387.11 KXT06934.1 - 0.65 9.0 2.0 1.6 7.7 0.1 2.5 3 0 0 3 3 3 0 Seadornavirus VP7 Mito_carr PF00153.27 KXT06935.1 - 7.1e-38 128.4 6.3 4.2e-14 52.2 0.1 4.2 3 1 0 3 3 3 3 Mitochondrial carrier protein He_PIG PF05345.12 KXT06936.1 - 1.1e-19 70.3 12.8 3.4e-07 30.4 2.1 5.2 5 0 0 5 5 5 3 Putative Ig domain DUF4690 PF15756.5 KXT06936.1 - 0.00038 21.0 0.3 0.0016 19.0 0.3 2.1 1 0 0 1 1 1 1 Small Novel Rich in Cartilage TMEM154 PF15102.6 KXT06936.1 - 0.026 14.4 2.0 0.029 14.3 0.2 2.1 2 0 0 2 2 2 0 TMEM154 protein family Couple_hipA PF13657.6 KXT06936.1 - 0.032 14.9 0.1 0.14 12.8 0.0 2.1 1 1 1 2 2 2 0 HipA N-terminal domain Glycophorin_A PF01102.18 KXT06936.1 - 0.04 14.1 1.9 0.058 13.6 0.1 2.2 2 0 0 2 2 2 0 Glycophorin A Sarcoglycan_2 PF05510.13 KXT06936.1 - 0.13 11.0 0.0 0.4 9.4 0.0 1.8 2 0 0 2 2 2 0 Sarcoglycan alpha/epsilon CcmD PF04995.14 KXT06936.1 - 2 8.6 4.9 6 7.0 4.9 1.8 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) ECH_1 PF00378.20 KXT06940.1 - 2.6e-28 99.0 0.0 4.4e-28 98.3 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXT06940.1 - 2.7e-15 56.7 0.0 3e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Glyco_transf_8 PF01501.20 KXT06941.1 - 4.8e-12 46.0 0.0 1.6e-11 44.2 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 8 Methyltransf_16 PF10294.9 KXT06942.1 - 9.7e-19 67.7 0.2 7.3e-18 64.9 0.2 2.0 1 1 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 KXT06942.1 - 1.6e-09 37.6 0.0 2.4e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KXT06942.1 - 4.2e-07 29.7 0.0 8.5e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KXT06942.1 - 2.1e-06 28.3 0.0 4.2e-05 24.2 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXT06942.1 - 0.00062 19.6 0.0 0.001 18.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXT06942.1 - 0.0016 19.1 0.1 0.0044 17.7 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KXT06942.1 - 0.0026 17.4 0.0 0.0048 16.6 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Met_10 PF02475.16 KXT06942.1 - 0.0033 17.2 0.0 0.0057 16.4 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein ADH_zinc_N PF00107.26 KXT06942.1 - 0.0097 15.9 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 KXT06942.1 - 0.013 15.3 0.0 0.03 14.2 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 KXT06942.1 - 0.015 15.1 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Spermine_synth PF01564.17 KXT06942.1 - 0.025 14.0 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 Spermine/spermidine synthase domain Methyltransf_11 PF08241.12 KXT06942.1 - 0.036 14.7 0.0 0.096 13.4 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 KXT06942.1 - 0.043 12.9 0.0 0.076 12.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DUF938 PF06080.12 KXT06942.1 - 0.084 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) MRP-L27 PF09809.9 KXT06943.1 - 2.5e-19 69.2 0.3 3.1e-19 68.9 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Phage_Integr_2 PF13009.6 KXT06943.1 - 0.11 11.6 0.2 0.14 11.2 0.2 1.1 1 0 0 1 1 1 0 Putative phage integrase MFS_1 PF07690.16 KXT06944.1 - 9.1e-34 116.9 16.8 9.1e-34 116.9 16.8 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily CagY_M PF07337.11 KXT06944.1 - 0.15 11.7 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 DC-EC Repeat ThiF PF00899.21 KXT06945.1 - 1.1e-38 133.0 0.0 2.3e-38 131.9 0.0 1.5 2 0 0 2 2 2 1 ThiF family Peptidase_A25 PF03418.14 KXT06945.1 - 0.015 14.3 0.0 0.028 13.3 0.0 1.4 1 0 0 1 1 1 0 Germination protease TrkA_N PF02254.18 KXT06945.1 - 0.025 14.8 0.0 0.071 13.4 0.0 1.8 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.6 KXT06945.1 - 0.11 12.9 0.0 0.33 11.4 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 KXT06945.1 - 0.21 11.1 0.1 0.63 9.6 0.0 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain OAD_gamma PF04277.13 KXT06946.1 - 3.2 8.4 5.9 0.63 10.7 0.8 2.2 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF4712 PF15830.5 KXT06946.1 - 9.6 5.8 9.0 24 4.5 9.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4712) DUF1156 PF06634.12 KXT06947.1 - 0.14 12.3 1.1 0.28 11.3 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1156) SWIRM-assoc_2 PF16496.5 KXT06948.1 - 2.6 6.8 6.1 10 4.9 0.0 3.0 3 0 0 3 3 3 0 SWIRM-associated domain at the N-terminal Coa1 PF08695.10 KXT06949.1 - 6.9e-41 138.7 0.0 1.1e-40 138.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Sporozoite_P67 PF05642.11 KXT06951.1 - 0.21 9.7 2.6 0.24 9.4 2.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FSA_C PF10479.9 KXT06951.1 - 1.5 6.9 6.1 1.9 6.5 6.1 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus SR-25 PF10500.9 KXT06951.1 - 4.8 6.7 9.5 7.1 6.2 9.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Transp_cyt_pur PF02133.15 KXT06952.1 - 1.4e-103 347.1 37.0 1.6e-103 346.8 37.0 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Transp_cyt_pur PF02133.15 KXT06954.1 - 1.4e-103 347.1 37.0 1.6e-103 346.8 37.0 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin BLOC1_2 PF10046.9 KXT06955.1 - 0.025 14.9 1.0 1.1 9.6 0.2 2.4 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 IFT20 PF14931.6 KXT06955.1 - 0.03 14.5 3.2 0.74 10.0 0.0 2.1 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 GTA_holin_3TM PF11351.8 KXT06955.1 - 0.041 14.4 0.3 0.068 13.7 0.3 1.3 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release PPR_3 PF13812.6 KXT06955.1 - 0.11 12.6 0.1 0.21 11.7 0.1 1.5 1 0 0 1 1 1 0 Pentatricopeptide repeat domain TSC22 PF01166.18 KXT06955.1 - 0.2 12.0 1.6 7.4 7.0 0.0 3.0 3 0 0 3 3 3 0 TSC-22/dip/bun family Lipoprotein_7 PF01540.16 KXT06955.1 - 0.35 10.1 2.1 0.23 10.7 0.4 1.4 2 0 0 2 2 2 0 Adhesin lipoprotein Alanine_zipper PF11839.8 KXT06956.1 - 0.0093 16.3 18.5 0.0093 16.3 18.5 5.0 4 1 2 6 6 5 2 Alanine-zipper, major outer membrane lipoprotein Tropomyosin PF00261.20 KXT06956.1 - 0.32 10.3 54.5 0.72 9.2 6.3 4.0 1 1 0 2 2 2 0 Tropomyosin EzrA PF06160.12 KXT06956.1 - 0.57 8.3 33.0 0.45 8.6 11.6 2.4 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA OEP PF02321.18 KXT06956.1 - 0.89 9.3 30.9 0.4 10.5 17.4 3.3 1 1 2 3 3 3 0 Outer membrane efflux protein WEMBL PF05701.11 KXT06956.1 - 0.98 8.0 50.7 0.75 8.4 16.4 3.2 1 1 2 3 3 3 0 Weak chloroplast movement under blue light YscO PF07321.12 KXT06956.1 - 1.1 9.2 48.5 0.67 9.9 9.3 3.5 1 1 2 3 3 3 0 Type III secretion protein YscO Laminin_II PF06009.12 KXT06956.1 - 1.2 9.1 31.6 0.13 12.3 3.5 3.7 1 1 1 3 3 3 0 Laminin Domain II HAUS-augmin3 PF14932.6 KXT06956.1 - 1.7 8.1 35.3 0.025 14.1 9.6 2.4 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 GAS PF13851.6 KXT06956.1 - 4.3 6.6 42.0 1 8.6 18.5 3.1 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.10 KXT06956.1 - 6.2 7.0 26.6 2.9 8.1 4.5 3.3 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF2703 PF10865.8 KXT06956.1 - 9.6 6.4 11.7 0.82 9.9 0.7 3.4 2 1 2 4 4 4 0 Domain of unknown function (DUF2703) KilA-N PF04383.13 KXT06957.1 - 0.075 12.9 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 KilA-N domain L31 PF09784.9 KXT06958.1 - 1.1e-41 141.4 1.6 7.4e-23 80.9 0.1 2.1 2 0 0 2 2 2 2 Mitochondrial ribosomal protein L31 FAD_binding_3 PF01494.19 KXT06959.1 - 9.9e-19 67.8 0.0 8.2e-11 41.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KXT06959.1 - 0.00026 21.2 0.0 0.00055 20.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXT06959.1 - 0.0068 15.7 0.0 0.27 10.4 0.0 2.7 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KXT06959.1 - 0.024 13.9 0.0 0.053 12.8 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXT06959.1 - 0.094 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Aldo_ket_red PF00248.21 KXT06961.1 - 6.5e-50 170.0 0.0 4e-49 167.4 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family Semialdhyde_dh PF01118.24 KXT06961.1 - 0.028 14.9 0.0 0.25 11.8 0.0 2.3 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Rnk_N PF14760.6 KXT06961.1 - 0.14 12.6 0.0 0.29 11.7 0.0 1.5 1 0 0 1 1 1 0 Rnk N-terminus Myosin_head PF00063.21 KXT06962.1 - 3.3e-269 894.8 3.4 5.2e-269 894.1 0.0 2.5 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_N PF02736.19 KXT06962.1 - 1.6e-08 34.2 0.0 4.2e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Myosin_tail_1 PF01576.19 KXT06962.1 - 2.7e-06 25.5 105.7 2.7e-06 25.5 105.7 8.1 2 2 2 4 4 4 2 Myosin tail TMF_TATA_bd PF12325.8 KXT06962.1 - 0.00089 19.5 11.5 0.00089 19.5 11.5 16.3 3 2 6 15 15 15 1 TATA element modulatory factor 1 TATA binding TPR_MLP1_2 PF07926.12 KXT06962.1 - 0.0036 17.4 18.3 0.0036 17.4 18.3 15.4 5 2 9 15 15 15 5 TPR/MLP1/MLP2-like protein AAA_22 PF13401.6 KXT06962.1 - 0.062 13.6 0.0 0.062 13.6 0.0 5.3 4 0 0 4 4 4 0 AAA domain IQ PF00612.27 KXT06962.1 - 0.14 12.0 2.3 0.52 10.3 2.3 2.1 1 0 0 1 1 1 0 IQ calmodulin-binding motif ABC2_membrane PF01061.24 KXT06963.1 - 2.1e-91 305.1 63.0 7.1e-49 166.1 22.4 3.4 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.12 KXT06963.1 - 2.3e-38 130.0 2.9 1.7e-33 114.3 0.1 3.5 4 0 0 4 4 2 2 CDR ABC transporter ABC_tran PF00005.27 KXT06963.1 - 2.5e-36 125.2 0.0 3e-17 63.4 0.0 3.4 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.6 KXT06963.1 - 5.3e-17 62.2 0.2 1.3e-16 60.9 0.2 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_33 PF13671.6 KXT06963.1 - 1.6e-06 28.3 0.3 0.0019 18.3 0.1 2.7 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KXT06963.1 - 2.7e-06 27.4 0.1 0.0003 20.7 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KXT06963.1 - 9.6e-06 26.1 0.1 0.0039 17.6 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 KXT06963.1 - 1.8e-05 25.3 0.0 0.0047 17.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KXT06963.1 - 2e-05 24.3 1.0 0.00023 20.8 0.3 2.6 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KXT06963.1 - 0.0003 21.2 0.3 0.034 14.6 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KXT06963.1 - 0.00069 19.3 1.8 0.032 14.0 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.6 KXT06963.1 - 0.0011 18.8 0.1 0.24 11.1 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KXT06963.1 - 0.0026 17.6 0.3 1.1 9.0 0.0 2.9 2 1 1 3 3 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXT06963.1 - 0.0034 16.9 0.0 0.5 9.8 0.0 3.3 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KXT06963.1 - 0.0053 17.0 0.1 2.4 8.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KXT06963.1 - 0.024 15.0 0.1 13 6.2 0.0 3.1 3 0 0 3 3 3 0 RNA helicase cobW PF02492.19 KXT06963.1 - 0.025 14.2 0.5 0.55 9.8 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Ploopntkinase3 PF18751.1 KXT06963.1 - 0.043 13.7 0.1 0.37 10.7 0.0 2.1 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 NACHT PF05729.12 KXT06963.1 - 0.061 13.2 0.4 2.7 7.9 0.2 2.4 2 0 0 2 2 2 0 NACHT domain Rad17 PF03215.15 KXT06963.1 - 0.064 13.2 0.0 3.5 7.5 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_24 PF13479.6 KXT06963.1 - 0.22 11.2 1.6 18 5.0 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 KXT06963.1 - 0.23 11.7 0.6 8.1 6.7 0.0 3.0 3 0 0 3 3 3 0 AAA domain IF-2B PF01008.17 KXT06964.1 - 1.7e-55 188.2 4.8 1.2e-30 106.7 0.1 3.2 3 1 0 3 3 3 2 Initiation factor 2 subunit family PS_pyruv_trans PF04230.13 KXT06965.1 - 0.084 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide pyruvyl transferase DUF4083 PF13314.6 KXT06966.1 - 0.22 11.5 0.8 2.6 8.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) Utp14 PF04615.13 KXT06967.1 - 4.4e-180 600.9 72.4 4.4e-180 600.9 72.4 2.3 1 1 1 2 2 2 1 Utp14 protein Lectin_leg-like PF03388.13 KXT06968.1 - 2e-70 236.7 0.0 2.7e-70 236.3 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.19 KXT06968.1 - 0.00047 19.8 0.1 0.36 10.3 0.0 2.2 2 0 0 2 2 2 2 Legume lectin domain ATG27 PF09451.10 KXT06968.1 - 0.0025 17.7 0.0 0.0039 17.1 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 27 FGGY_C PF02782.16 KXT06969.1 - 8.6e-74 247.5 1.4 2.3e-73 246.2 1.6 1.6 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KXT06969.1 - 3.2e-62 210.3 0.0 4.5e-62 209.8 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain DNA_pol_B_thumb PF14791.6 KXT06970.1 - 8.1e-23 80.4 0.4 1.9e-22 79.2 0.4 1.7 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 KXT06970.1 - 1e-19 70.1 1.0 3.3e-19 68.5 0.4 2.2 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda DNA_pol_B_palm PF14792.6 KXT06970.1 - 3.7e-19 69.0 0.1 1.9e-18 66.7 0.1 2.1 1 1 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.6 KXT06970.1 - 6.1e-09 36.1 0.1 1.6e-08 34.8 0.1 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_5 PF14520.6 KXT06970.1 - 0.015 15.9 0.0 1.2 9.8 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 KXT06970.1 - 0.086 13.1 0.0 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 Nucleotidyltransferase domain Pro_CA PF00484.19 KXT06971.1 - 1.9e-44 151.7 0.0 2.7e-44 151.2 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase GGACT PF06094.12 KXT06971.1 - 0.016 15.8 0.5 0.06 14.0 0.5 2.0 1 1 1 2 2 2 0 Gamma-glutamyl cyclotransferase, AIG2-like Ras PF00071.22 KXT06972.1 - 3.8e-53 179.4 0.0 4.7e-53 179.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KXT06972.1 - 7.2e-19 68.2 0.0 1e-18 67.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KXT06972.1 - 3.3e-06 26.7 0.0 4.5e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KXT06972.1 - 0.066 12.7 0.1 0.37 10.3 0.0 2.1 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain MFS_1 PF07690.16 KXT06973.1 - 1.9e-18 66.5 52.1 3.1e-11 42.8 25.9 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily NCBP3 PF10309.9 KXT06974.1 - 8.9e-19 67.1 0.5 1.5e-18 66.4 0.5 1.4 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 HeLo PF14479.6 KXT06976.1 - 1.9e-07 31.2 1.7 0.00093 19.1 0.1 3.6 4 0 0 4 4 4 2 Prion-inhibition and propagation TFIIA PF03153.13 KXT06976.1 - 0.0016 18.6 2.5 0.0016 18.6 2.5 1.9 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Med18 PF09637.10 KXT06977.1 - 7.9e-29 101.2 0.0 1.1e-28 100.7 0.0 1.2 1 0 0 1 1 1 1 Med18 protein MFS_1 PF07690.16 KXT06978.1 - 2.3e-31 109.0 50.4 7.1e-31 107.4 45.9 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily CLN3 PF02487.17 KXT06978.1 - 0.0016 17.6 6.7 0.0016 17.5 5.4 1.6 1 1 0 1 1 1 1 CLN3 protein DUF4121 PF13497.6 KXT06978.1 - 0.22 10.6 0.0 0.35 10.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4121) SET_assoc PF11767.8 KXT06979.1 - 3e-06 26.8 0.0 6.8e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated PHD PF00628.29 KXT06979.1 - 9.9e-05 22.2 10.4 9.9e-05 22.2 10.4 2.5 2 0 0 2 2 2 1 PHD-finger Forkhead PF00250.18 KXT06979.1 - 0.00011 22.3 0.0 0.00023 21.4 0.0 1.5 1 0 0 1 1 1 1 Forkhead domain PHD_4 PF16866.5 KXT06979.1 - 0.48 10.6 13.4 0.028 14.5 5.6 2.9 2 1 0 2 2 2 0 PHD-finger PHD_2 PF13831.6 KXT06979.1 - 6.7 6.4 7.6 1.7 8.2 3.7 2.1 2 0 0 2 2 2 0 PHD-finger zf-RING-like PF08746.11 KXT06979.1 - 6.8 7.1 9.6 20 5.6 9.6 1.9 1 0 0 1 1 1 0 RING-like domain MFS_1 PF07690.16 KXT06980.1 - 7.4e-27 94.2 32.0 9.8e-27 93.8 32.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXT06980.1 - 4.5e-12 45.6 12.5 4.5e-12 45.6 12.5 1.5 2 0 0 2 2 2 1 Sugar (and other) transporter PHF5 PF03660.14 KXT06981.1 - 1.9e-51 172.6 10.3 2.1e-51 172.5 10.3 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 KXT06981.1 - 0.69 7.7 7.7 0.63 7.8 7.1 1.3 1 1 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 KXT06981.1 - 4.7 7.3 16.2 6.4 6.9 2.2 3.0 1 1 1 2 2 2 0 Double zinc ribbon PHF5 PF03660.14 KXT06982.1 - 1.9e-51 172.6 10.3 2.1e-51 172.5 10.3 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 KXT06982.1 - 0.69 7.7 7.7 0.63 7.8 7.1 1.3 1 1 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 KXT06982.1 - 4.7 7.3 16.2 6.4 6.9 2.2 3.0 1 1 1 2 2 2 0 Double zinc ribbon PHF5 PF03660.14 KXT06983.1 - 1.9e-51 172.6 10.3 2.1e-51 172.5 10.3 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 KXT06983.1 - 0.69 7.7 7.7 0.63 7.8 7.1 1.3 1 1 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 KXT06983.1 - 4.7 7.3 16.2 6.4 6.9 2.2 3.0 1 1 1 2 2 2 0 Double zinc ribbon Methyltransf_2 PF00891.18 KXT06984.1 - 7.8e-28 97.2 0.0 1.6e-27 96.2 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase domain FAD_binding_3 PF01494.19 KXT06984.1 - 9.4e-20 71.1 0.1 3.5e-13 49.5 0.2 3.1 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KXT06984.1 - 4.5e-05 23.6 0.0 0.00014 22.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Methyltransf_12 PF08242.12 KXT06984.1 - 0.00032 21.4 0.0 0.00077 20.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXT06984.1 - 0.0013 19.4 0.0 0.0031 18.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Pyr_redox PF00070.27 KXT06984.1 - 0.013 16.0 0.0 0.23 12.0 0.0 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXT06984.1 - 0.032 13.3 0.3 1.5 7.8 0.0 2.8 3 0 0 3 3 3 0 Lycopene cyclase protein Methyltransf_16 PF10294.9 KXT06984.1 - 0.046 13.5 0.1 0.38 10.5 0.0 2.3 2 0 0 2 2 2 0 Lysine methyltransferase Pyr_redox_2 PF07992.14 KXT06984.1 - 0.17 11.1 0.0 9.7 5.3 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Zn_clus PF00172.18 KXT06985.1 - 8.8e-08 32.1 10.4 1.9e-07 31.0 10.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AflR PF08493.10 KXT06985.1 - 2.3e-05 24.0 1.5 3.6e-05 23.4 1.5 1.3 1 0 0 1 1 1 1 Aflatoxin regulatory protein EutB PF06751.11 KXT06985.1 - 0.049 12.5 0.0 0.075 11.8 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine ammonia lyase large subunit (EutB) Zn_clus PF00172.18 KXT06986.1 - 8.4e-08 32.2 10.4 1.9e-07 31.1 10.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AflR PF08493.10 KXT06986.1 - 2.3e-05 24.0 1.5 3.5e-05 23.4 1.5 1.3 1 0 0 1 1 1 1 Aflatoxin regulatory protein EutB PF06751.11 KXT06986.1 - 0.05 12.4 0.0 0.075 11.9 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine ammonia lyase large subunit (EutB) MFS_1 PF07690.16 KXT06987.1 - 4.8e-43 147.4 46.5 4.8e-43 147.4 46.5 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXT06987.1 - 8.1e-08 31.5 12.9 8.1e-08 31.5 12.9 3.6 3 2 2 5 5 5 1 Sugar (and other) transporter OppC_N PF12911.7 KXT06987.1 - 0.65 10.0 0.1 0.65 10.0 0.1 3.6 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C NIF PF03031.18 KXT06988.1 - 3.3e-53 179.6 0.0 4.7e-53 179.1 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Presenilin PF01080.17 KXT06988.1 - 0.067 11.9 0.3 0.084 11.6 0.3 1.2 1 0 0 1 1 1 0 Presenilin NIPSNAP PF07978.13 KXT06988.1 - 0.076 13.3 0.0 0.23 11.7 0.0 1.8 1 0 0 1 1 1 0 NIPSNAP Hid1 PF12722.7 KXT06988.1 - 5.1 5.1 7.9 6.7 4.7 7.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MCU PF04678.13 KXT06989.1 - 2.8e-25 89.4 0.1 2.8e-25 89.4 0.1 1.9 2 0 0 2 2 2 1 Mitochondrial calcium uniporter Granulin PF00396.18 KXT06989.1 - 7.8 6.9 15.5 9.4 6.7 5.0 2.3 1 1 1 2 2 2 0 Granulin SANT_DAMP1_like PF16282.5 KXT06990.1 - 6.5e-27 93.6 2.8 1.3e-26 92.6 2.8 1.5 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_6 PF13921.6 KXT06990.1 - 6.6e-06 26.3 1.4 1.9e-05 24.8 0.1 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KXT06990.1 - 0.0096 16.1 0.1 0.021 15.0 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KXT06990.1 - 0.033 14.6 0.0 0.15 12.4 0.0 2.2 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 KXT06990.1 - 0.048 13.7 0.1 0.77 9.9 0.0 2.9 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain CENP-B_dimeris PF09026.10 KXT06991.1 - 0.73 10.3 25.0 0.53 10.7 11.3 3.3 3 0 0 3 3 3 0 Centromere protein B dimerisation domain COX7C PF02935.16 KXT06993.1 - 4.6e-24 84.4 4.3 5.4e-24 84.2 4.3 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc AMP-binding PF00501.28 KXT06994.1 - 1.1e-77 261.4 0.0 1.5e-77 261.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXT06994.1 - 3.2e-14 53.7 0.0 6.3e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Na_Ca_ex PF01699.24 KXT06995.1 - 6.7e-46 156.0 38.6 1.3e-23 83.6 16.1 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Na_Ca_ex PF01699.24 KXT06996.1 - 5e-46 156.4 38.6 1.2e-23 83.8 16.1 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Zn_clus PF00172.18 KXT06998.1 - 8.3e-09 35.4 8.1 8.3e-09 35.4 8.1 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KXT06998.1 - 5.6e-07 28.7 0.1 1e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MerR PF00376.23 KXT06999.1 - 0.063 13.1 0.1 0.31 10.8 0.1 2.2 1 0 0 1 1 1 0 MerR family regulatory protein DUF1664 PF07889.12 KXT06999.1 - 0.12 12.5 1.4 2 8.5 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) HR1 PF02185.16 KXT06999.1 - 7.9 6.7 11.4 4.3 7.5 3.2 3.0 2 1 1 3 3 3 0 Hr1 repeat Oxidored_molyb PF00174.19 KXT07000.1 - 6.6e-12 45.4 0.0 1.7e-11 44.1 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KXT07000.1 - 0.057 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain Abhydrolase_3 PF07859.13 KXT07001.1 - 6e-31 107.9 0.0 8.9e-31 107.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KXT07001.1 - 1.3e-09 37.4 0.0 1.5e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase DUF2974 PF11187.8 KXT07001.1 - 0.0071 15.9 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Peptidase_S9 PF00326.21 KXT07001.1 - 0.012 15.1 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family BAAT_C PF08840.11 KXT07001.1 - 0.061 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal COesterase PF00135.28 KXT07001.1 - 0.19 10.6 0.1 0.43 9.4 0.1 1.5 1 1 0 1 1 1 0 Carboxylesterase family AXE1 PF05448.12 KXT07001.1 - 0.21 10.2 0.0 0.36 9.4 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) PepSY_2 PF13670.6 KXT07004.1 - 0.34 10.9 3.0 9.5 6.3 0.1 2.4 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Siah-Interact_N PF09032.11 KXT07006.1 - 3 8.2 7.1 5.9 7.3 2.0 2.9 2 0 0 2 2 2 0 Siah interacting protein, N terminal RIFIN PF02009.16 KXT07008.1 - 0.006 16.5 0.0 0.0071 16.3 0.0 1.0 1 0 0 1 1 1 1 Rifin Meckelin PF09773.9 KXT07008.1 - 0.0065 14.6 0.1 0.0074 14.4 0.1 1.0 1 0 0 1 1 1 1 Meckelin (Transmembrane protein 67) TNFR_16_TM PF18422.1 KXT07008.1 - 0.0071 16.3 0.3 0.011 15.7 0.3 1.3 1 0 0 1 1 1 1 Tumor necrosis factor receptor member 16 trans-membrane domain UDPGT PF00201.18 KXT07008.1 - 0.011 14.6 0.1 0.012 14.4 0.1 1.1 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase DUF1180 PF06679.12 KXT07008.1 - 0.016 15.6 0.0 0.018 15.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) GT87 PF09594.10 KXT07008.1 - 0.025 14.3 0.0 0.028 14.1 0.0 1.0 1 0 0 1 1 1 0 Glycosyltransferase family 87 DUF5305 PF17231.2 KXT07008.1 - 0.085 12.2 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) GRA6 PF05084.13 KXT07008.1 - 0.087 12.8 0.1 0.13 12.2 0.1 1.4 1 1 0 1 1 1 0 Granule antigen protein (GRA6) MGC-24 PF05283.11 KXT07008.1 - 0.11 13.0 0.1 0.13 12.7 0.1 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF2681 PF10883.8 KXT07008.1 - 0.16 12.4 0.1 0.27 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) DUF4083 PF13314.6 KXT07008.1 - 0.18 11.8 1.3 2.5 8.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) Zip PF02535.22 KXT07009.1 - 5.6e-32 111.3 22.7 1.6e-29 103.2 22.7 3.1 1 1 0 1 1 1 1 ZIP Zinc transporter Mcp5_PH PF12814.7 KXT07010.1 - 3.3e-45 153.1 0.2 8.7e-45 151.8 0.2 1.8 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 KXT07010.1 - 0.00031 21.2 0.0 0.00076 20.0 0.0 1.6 1 0 0 1 1 1 1 PH domain adh_short_C2 PF13561.6 KXT07011.1 - 1.3e-38 132.9 0.0 2.1e-38 132.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXT07011.1 - 3.8e-38 130.9 0.0 5.5e-38 130.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXT07011.1 - 0.00055 19.9 0.1 0.00087 19.2 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KXT07011.1 - 0.003 17.5 0.0 0.0061 16.5 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXT07011.1 - 0.015 14.7 0.0 0.031 13.7 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family zinc_ribbon_6 PF14599.6 KXT07012.1 - 6.5e-18 64.5 3.3 5.7e-15 55.1 0.2 5.8 4 2 1 5 5 5 2 Zinc-ribbon zf-CHY PF05495.12 KXT07012.1 - 5.6e-16 58.8 22.4 5.6e-16 58.8 22.4 4.1 3 1 1 4 4 4 1 CHY zinc finger zf-RING_2 PF13639.6 KXT07012.1 - 4.6e-08 33.3 3.5 4.6e-08 33.3 3.5 4.5 3 1 0 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXT07012.1 - 0.00017 21.3 6.0 0.00017 21.3 6.0 4.1 5 1 0 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXT07012.1 - 0.01 15.8 12.9 0.01 15.8 12.9 5.0 2 2 1 3 3 3 0 zinc-RING finger domain zf-RING_11 PF17123.5 KXT07012.1 - 0.017 14.8 1.0 0.017 14.8 1.0 3.4 4 0 0 4 4 4 0 RING-like zinc finger PLDc_N PF13396.6 KXT07014.1 - 1.4e-09 37.7 9.7 1.4e-09 37.7 9.7 1.5 2 0 0 2 2 2 1 Phospholipase_D-nuclease N-terminal Orai-1 PF07856.12 KXT07014.1 - 0.0098 15.6 1.9 0.011 15.5 1.9 1.1 1 0 0 1 1 1 1 Mediator of CRAC channel activity DUF2207 PF09972.9 KXT07014.1 - 0.027 13.2 0.9 0.03 13.1 0.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Pox_A14 PF05767.12 KXT07014.1 - 0.044 13.9 0.4 0.058 13.5 0.4 1.2 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 Sugar_tr PF00083.24 KXT07015.1 - 1.6e-103 347.0 13.7 1.9e-103 346.7 13.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXT07015.1 - 3.1e-29 102.0 24.4 3.1e-29 102.0 24.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KXT07015.1 - 1.3e-06 27.5 0.0 0.0048 15.8 0.1 3.3 2 2 1 3 3 3 2 MFS_1 like family TRI12 PF06609.13 KXT07015.1 - 1.9e-05 23.3 2.5 2.8e-05 22.7 2.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Phage_holin_3_2 PF04550.12 KXT07015.1 - 0.034 14.7 2.5 0.14 12.7 2.5 2.1 1 0 0 1 1 1 0 Phage holin family 2 DUF2933 PF11666.8 KXT07015.1 - 0.042 13.9 0.2 1.6 8.8 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2933) DUF3405 PF11885.8 KXT07016.1 - 3.9e-231 768.1 8.6 4.8e-231 767.8 8.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) DPBB_1 PF03330.18 KXT07017.1 - 0.00021 21.5 0.0 0.0005 20.3 0.0 1.7 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KXT07017.1 - 0.0029 17.5 0.2 0.0044 16.9 0.2 1.3 1 0 0 1 1 1 1 Barwin family SOG2 PF10428.9 KXT07017.1 - 2.4 7.3 9.3 2.7 7.1 9.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein FPP PF05911.11 KXT07018.1 - 0.0014 16.9 5.0 0.0018 16.6 5.0 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil Rogdi_lz PF10259.9 KXT07018.1 - 0.0022 17.5 4.0 0.0036 16.8 4.0 1.3 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Mating_N PF12731.7 KXT07018.1 - 0.017 15.2 1.7 0.031 14.3 0.1 2.2 3 0 0 3 3 3 0 Mating-type protein beta 1 BLOC1_2 PF10046.9 KXT07018.1 - 1.2 9.5 4.4 11 6.4 0.4 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 KXT07018.1 - 1.8 8.6 6.7 1.4 9.0 3.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 KXT07018.1 - 1.9 8.7 13.3 0.81 9.9 8.0 2.6 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family Abhydrolase_1 PF00561.20 KXT07019.1 - 2.1e-42 145.5 0.0 8.3e-42 143.6 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KXT07019.1 - 0.019 14.6 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 Putative esterase adh_short PF00106.25 KXT07020.1 - 7.7e-40 136.4 0.0 1.2e-39 135.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT07020.1 - 9.2e-31 107.2 0.0 1.2e-30 106.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT07020.1 - 1.8e-06 28.0 0.1 4.5e-06 26.7 0.1 1.7 1 1 0 1 1 1 1 KR domain Methyltransf_25 PF13649.6 KXT07020.1 - 0.012 16.3 0.0 0.024 15.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain 3Beta_HSD PF01073.19 KXT07020.1 - 0.061 12.3 0.1 0.091 11.7 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_7 PF13241.6 KXT07020.1 - 0.093 13.2 0.3 0.24 11.9 0.1 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding Epimerase PF01370.21 KXT07020.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family MHYT PF03707.16 KXT07021.1 - 1.1e-21 76.8 4.9 9.1e-09 35.4 0.1 4.8 4 0 0 4 4 4 4 Bacterial signalling protein N terminal repeat DUF4328 PF14219.6 KXT07021.1 - 0.23 11.0 5.8 1.6 8.3 1.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) MHYT PF03707.16 KXT07022.1 - 1.1e-21 76.8 4.9 9.1e-09 35.4 0.1 4.8 4 0 0 4 4 4 4 Bacterial signalling protein N terminal repeat DUF4328 PF14219.6 KXT07022.1 - 0.23 11.0 5.8 1.6 8.3 1.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) Sedlin_N PF04628.13 KXT07023.1 - 9.7e-44 148.7 0.0 1.2e-43 148.4 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 KXT07023.1 - 6e-06 26.2 0.0 0.00068 19.6 0.0 2.2 2 0 0 2 2 2 2 Sybindin-like family ArfA PF03889.13 KXT07023.1 - 0.18 11.3 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 Alternative ribosome-rescue factor A Ketoacyl-synt_2 PF13723.6 KXT07024.1 - 0.068 12.8 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain LRR_4 PF12799.7 KXT07025.1 - 0.21 12.1 4.2 8.1 7.0 0.2 4.3 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) EST1_DNA_bind PF10373.9 KXT07026.1 - 1.4e-06 28.0 0.0 3.7e-06 26.6 0.0 1.7 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain DUF1769 PF08588.10 KXT07027.1 - 1.8e-25 88.9 0.1 3.8e-25 87.9 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) ATP_bind_3 PF01171.20 KXT07028.1 - 1e-17 64.5 0.0 1.8e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 KXT07028.1 - 3.4e-17 61.6 2.7 3.4e-17 61.6 2.7 2.2 2 0 0 2 2 2 1 Zinc-ribbon RecR PF02132.15 KXT07028.1 - 0.0029 17.2 0.7 0.0075 15.8 0.7 1.7 1 0 0 1 1 1 1 RecR protein tRNA_Me_trans PF03054.16 KXT07028.1 - 0.066 12.0 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase HEAT PF02985.22 KXT07029.1 - 0.0017 18.4 1.2 1.5 9.3 0.0 5.0 6 0 0 6 6 6 1 HEAT repeat Gly_transf_sug PF04488.15 KXT07030.1 - 9.6e-14 51.8 0.0 1.9e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Gly_transf_sug PF04488.15 KXT07031.1 - 9.6e-14 51.8 0.0 1.9e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif eIF-5_eIF-2B PF01873.17 KXT07032.1 - 7.5e-41 138.7 0.0 1.5e-40 137.7 0.0 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 KXT07032.1 - 3e-21 75.3 0.3 3e-21 75.3 0.3 2.2 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Thiolase_N PF00108.23 KXT07033.1 - 7.8e-74 248.3 0.8 7.8e-74 248.3 0.8 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KXT07033.1 - 1.3e-44 150.8 0.1 2.4e-44 149.9 0.1 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KXT07033.1 - 0.0022 17.6 3.2 0.015 14.8 1.1 3.0 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Trigger_C PF05698.14 KXT07033.1 - 0.097 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus Pinin_SDK_memA PF04696.13 KXT07034.1 - 9.1e-26 90.4 12.9 9.1e-26 90.4 12.9 3.4 3 1 0 3 3 3 1 pinin/SDK/memA/ protein conserved region MMR_HSR1 PF01926.23 KXT07035.1 - 1.1e-13 51.3 0.0 2.1e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KXT07035.1 - 2.3e-05 24.4 0.7 6.9e-05 22.8 0.7 1.7 1 1 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 KXT07035.1 - 0.00034 20.7 0.1 0.072 13.1 0.1 2.4 1 1 1 2 2 2 2 Dynamin family FeoB_N PF02421.18 KXT07035.1 - 0.0005 19.6 0.0 0.00083 18.9 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 KXT07035.1 - 0.0015 18.9 0.0 0.0024 18.3 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 KXT07035.1 - 0.089 13.3 0.6 0.2 12.2 0.1 1.8 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 KXT07035.1 - 0.12 11.6 0.0 0.32 10.3 0.0 1.6 1 1 0 1 1 1 0 Septin FtsK_SpoIIIE PF01580.18 KXT07035.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family IIGP PF05049.13 KXT07035.1 - 0.13 11.3 0.1 0.21 10.6 0.1 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Roc PF08477.13 KXT07035.1 - 0.14 12.3 0.1 0.31 11.3 0.1 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 KXT07035.1 - 0.17 12.2 0.2 2.8 8.2 0.1 2.3 2 0 0 2 2 2 0 AAA domain Abhydrolase_1 PF00561.20 KXT07036.1 - 8.1e-23 81.4 0.2 1.6e-14 54.2 0.4 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXT07036.1 - 1.7e-13 51.7 0.0 2.6e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KXT07036.1 - 2.4e-06 27.0 0.2 8.7e-05 21.9 0.1 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 KXT07036.1 - 0.0088 15.8 0.1 1.9 8.2 0.1 2.4 2 1 0 2 2 2 2 Alpha/beta hydrolase family AMP-binding PF00501.28 KXT07038.1 - 5.8e-71 239.3 0.0 6.9e-71 239.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXT07038.1 - 2.3e-13 50.9 0.2 5e-13 49.8 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF5484 PF17583.2 KXT07038.1 - 0.22 11.2 1.3 0.74 9.5 1.3 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5484) Transket_pyr PF02779.24 KXT07039.1 - 3.2e-64 215.9 0.0 5.1e-64 215.2 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 KXT07039.1 - 4e-56 188.9 0.1 6.8e-56 188.2 0.1 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 KXT07039.1 - 6.6e-56 189.4 0.0 9.2e-56 189.0 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component 2-oxogl_dehyd_N PF16078.5 KXT07039.1 - 1.1e-19 69.7 1.8 2.4e-19 68.6 1.8 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus RAI16-like PF10257.9 KXT07040.1 - 5.3e-68 229.5 1.9 5.3e-68 229.5 1.9 1.8 2 0 0 2 2 2 1 Retinoic acid induced 16-like protein AflR PF08493.10 KXT07042.1 - 6.7e-09 35.6 0.1 1e-08 35.1 0.1 1.3 1 0 0 1 1 1 1 Aflatoxin regulatory protein Amido_AtzD_TrzD PF09663.10 KXT07043.1 - 1.3e-127 425.8 0.0 1.5e-127 425.6 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) zf-MYND PF01753.18 KXT07044.1 - 3.6e-09 36.5 14.4 9.4e-09 35.2 14.4 1.7 1 0 0 1 1 1 1 MYND finger DUF4259 PF14078.6 KXT07044.1 - 0.0082 16.9 0.0 0.015 16.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4259) WD40 PF00400.32 KXT07045.1 - 1.4e-41 139.7 19.1 2.7e-06 28.0 0.3 8.7 7 1 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 KXT07045.1 - 1.5e-12 47.2 0.2 3.1e-12 46.2 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXT07045.1 - 5.3e-11 42.1 0.1 1.3e-10 40.9 0.1 1.7 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 KXT07045.1 - 1.2e-06 27.5 7.2 0.36 9.4 0.1 5.1 2 1 2 5 5 5 4 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KXT07045.1 - 9.8e-06 25.8 0.2 1.1 9.6 0.0 4.3 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain F-box_4 PF15966.5 KXT07045.1 - 0.0019 18.1 0.0 0.0055 16.6 0.0 1.8 1 0 0 1 1 1 1 F-box WD40_like PF17005.5 KXT07045.1 - 0.0034 16.8 0.0 0.0048 16.3 0.0 1.1 1 0 0 1 1 1 1 WD40-like domain adh_short_C2 PF13561.6 KXT07047.1 - 3.2e-41 141.4 0.1 2.9e-40 138.3 0.1 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXT07047.1 - 2.9e-37 128.1 0.7 6.4e-36 123.7 0.7 2.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXT07047.1 - 7.7e-09 35.7 0.1 1.3e-08 34.9 0.1 1.4 1 0 0 1 1 1 1 KR domain NB-ARC PF00931.22 KXT07047.1 - 6.2e-05 22.3 0.0 0.00011 21.5 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_33 PF13671.6 KXT07047.1 - 0.00019 21.6 0.0 0.03 14.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain PRK PF00485.18 KXT07047.1 - 0.00053 19.8 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.6 KXT07047.1 - 0.0006 20.2 0.1 0.057 13.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KXT07047.1 - 0.0011 19.5 0.0 0.017 15.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KXT07047.1 - 0.0021 17.4 0.7 0.015 14.6 0.0 2.6 3 1 1 4 4 4 1 Zeta toxin AAA_16 PF13191.6 KXT07047.1 - 0.003 18.0 0.0 0.0062 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KXT07047.1 - 0.0033 17.7 0.0 0.009 16.3 0.0 1.7 2 0 0 2 2 1 1 AAA domain NACHT PF05729.12 KXT07047.1 - 0.004 17.1 0.0 0.0078 16.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain NTPase_1 PF03266.15 KXT07047.1 - 0.0086 16.0 0.1 0.027 14.4 0.0 1.9 2 0 0 2 2 1 1 NTPase AAA PF00004.29 KXT07047.1 - 0.0095 16.4 0.0 0.03 14.7 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Thymidylate_kin PF02223.17 KXT07047.1 - 0.011 15.4 0.0 0.039 13.6 0.0 1.9 2 0 0 2 2 2 0 Thymidylate kinase SRP54 PF00448.22 KXT07047.1 - 0.015 14.9 0.0 0.033 13.8 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_28 PF13521.6 KXT07047.1 - 0.024 14.9 0.0 0.067 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 KXT07047.1 - 0.031 14.0 0.0 0.065 13.0 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase KTI12 PF08433.10 KXT07047.1 - 0.046 13.2 0.0 0.083 12.3 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF2075 PF09848.9 KXT07047.1 - 0.049 12.9 0.0 0.082 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Epimerase PF01370.21 KXT07047.1 - 0.055 12.9 0.0 0.092 12.2 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXT07047.1 - 0.055 12.9 0.0 0.098 12.0 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase LDcluster4 PF18306.1 KXT07047.1 - 0.058 13.0 0.1 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 SLOG cluster4 family AAA_24 PF13479.6 KXT07047.1 - 0.079 12.7 0.5 1.9 8.2 0.0 3.0 4 0 0 4 4 3 0 AAA domain RGS PF00615.19 KXT07048.1 - 4.2e-30 104.4 0.0 9.8e-30 103.3 0.0 1.6 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.21 KXT07048.1 - 1.5e-19 69.8 0.0 6.2e-14 51.8 0.0 3.4 3 0 0 3 3 3 3 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Replic_Relax PF13814.6 KXT07048.1 - 0.0053 16.9 0.1 0.029 14.4 0.0 2.1 2 0 0 2 2 2 1 Replication-relaxation Sirohm_synth_M PF14824.6 KXT07048.1 - 0.076 12.5 3.3 0.28 10.7 1.0 2.5 2 0 0 2 2 2 0 Sirohaem biosynthesis protein central HATPase_c_3 PF13589.6 KXT07049.1 - 6e-13 48.8 0.0 1.3e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 KXT07049.1 - 5.3e-07 29.5 0.4 6.7e-06 25.9 0.1 2.5 2 1 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c PF02518.26 KXT07049.1 - 0.00018 22.0 0.0 0.00087 19.8 0.0 2.2 1 1 1 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pkinase PF00069.25 KXT07050.1 - 7.5e-55 186.1 0.0 9.6e-55 185.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT07050.1 - 9.8e-20 70.9 0.0 1.8e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KXT07050.1 - 0.0015 17.9 0.0 0.0024 17.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like AhpC-TSA PF00578.21 KXT07051.1 - 4.9e-25 87.8 0.0 7e-25 87.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KXT07051.1 - 1.2e-16 60.8 0.1 1.5e-16 60.5 0.1 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 KXT07051.1 - 0.00084 19.4 0.0 0.0028 17.8 0.0 1.7 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme DUF1180 PF06679.12 KXT07051.1 - 1.6 9.2 4.6 2.8 8.3 4.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF1761 PF08570.10 KXT07052.1 - 9.6e-28 96.9 4.2 1.1e-27 96.7 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) ADH_N PF08240.12 KXT07053.1 - 3.9e-29 100.7 1.0 9.2e-29 99.5 1.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXT07053.1 - 1.1e-23 83.6 0.1 2e-23 82.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXT07053.1 - 2.6e-09 36.9 0.1 3.2e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KXT07053.1 - 1.5e-05 26.0 0.0 2.8e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_7 PF13241.6 KXT07053.1 - 0.00021 21.7 0.0 0.00036 20.9 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 KXT07053.1 - 0.0011 19.3 0.0 0.0018 18.5 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 KXT07053.1 - 0.0064 16.0 0.1 0.011 15.2 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Shikimate_DH PF01488.20 KXT07053.1 - 0.019 15.0 0.0 0.035 14.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KXT07053.1 - 0.078 13.6 0.0 0.26 11.9 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KXT07053.1 - 0.1 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KXT07053.1 - 0.12 12.9 0.5 0.45 11.1 0.2 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3Beta_HSD PF01073.19 KXT07053.1 - 0.14 11.1 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family CNH PF00780.22 KXT07054.1 - 5.1e-69 232.9 0.0 1.1e-68 231.8 0.0 1.6 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.6 KXT07054.1 - 2.8e-44 150.5 0.0 7.3e-44 149.2 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 KXT07054.1 - 9.2e-39 133.6 0.2 1.9e-38 132.6 0.2 1.5 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 KXT07054.1 - 1.6e-13 50.5 0.0 3.2e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_13 PF16652.5 KXT07054.1 - 0.055 13.3 1.8 0.8 9.5 0.0 2.7 2 0 0 2 2 2 0 Pleckstrin homology domain DUF3087 PF11286.8 KXT07054.1 - 0.14 11.7 0.0 0.45 10.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) Acyl-CoA_dh_1 PF00441.24 KXT07063.1 - 2.9e-37 128.2 0.4 4.8e-37 127.5 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KXT07063.1 - 5.9e-20 71.3 0.1 1.1e-19 70.4 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KXT07063.1 - 4.5e-13 49.6 0.0 7.9e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KXT07063.1 - 3.5e-09 37.3 0.5 4.1e-08 33.9 0.5 2.5 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.8 KXT07063.1 - 3.6e-07 30.1 0.0 6.4e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Mst1_SARAH PF11629.8 KXT07063.1 - 0.28 11.3 1.2 0.92 9.6 0.1 2.1 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 HOOK PF05622.12 KXT07064.1 - 7.7e-19 67.3 66.4 1.4e-13 49.9 0.0 4.6 1 1 2 4 4 4 4 HOOK protein TPR_MLP1_2 PF07926.12 KXT07064.1 - 0.0023 18.0 21.1 0.0023 18.0 21.1 4.9 1 1 3 4 4 4 1 TPR/MLP1/MLP2-like protein HR1 PF02185.16 KXT07064.1 - 0.011 15.9 1.9 0.011 15.9 1.9 6.5 5 2 1 6 6 6 0 Hr1 repeat Sugarporin_N PF11471.8 KXT07064.1 - 0.014 15.3 9.5 0.41 10.6 5.2 3.2 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension CCDC-167 PF15188.6 KXT07064.1 - 0.022 15.1 5.9 0.022 15.1 5.9 5.4 3 1 2 5 5 5 0 Coiled-coil domain-containing protein 167 Phage_int_SAM_1 PF02899.17 KXT07064.1 - 0.055 13.8 0.5 0.055 13.8 0.5 3.3 3 1 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain TMF_DNA_bd PF12329.8 KXT07064.1 - 0.059 13.4 0.1 0.059 13.4 0.1 7.4 3 1 4 7 7 7 0 TATA element modulatory factor 1 DNA binding Halo_GVPC PF05465.13 KXT07064.1 - 0.2 11.9 1.6 8.8 6.7 0.1 3.3 3 0 0 3 3 3 0 Halobacterial gas vesicle protein C (GVPC) repeat Ribosomal_L31e PF01198.19 KXT07064.1 - 0.98 9.7 4.7 5.5 7.3 0.7 2.8 2 0 0 2 2 2 0 Ribosomal protein L31e DUF4051 PF13260.6 KXT07064.1 - 3.4 7.5 5.4 5.7 6.8 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) BshC PF10079.9 KXT07065.1 - 0.0074 15.1 3.9 0.0099 14.7 3.9 1.1 1 0 0 1 1 1 1 Bacillithiol biosynthesis BshC CK_II_beta PF01214.18 KXT07065.1 - 0.029 14.2 0.3 0.044 13.6 0.3 1.2 1 0 0 1 1 1 0 Casein kinase II regulatory subunit Jnk-SapK_ap_N PF09744.9 KXT07065.1 - 0.58 10.4 10.1 0.86 9.8 10.1 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 V_ATPase_I PF01496.19 KXT07065.1 - 1.7 6.5 4.5 2.3 6.0 4.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF5595 PF18077.1 KXT07065.1 - 2.7 8.2 5.3 1.2 9.3 2.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) XhlA PF10779.9 KXT07065.1 - 5.8 7.2 6.0 1.2 9.4 2.3 1.7 2 0 0 2 2 2 0 Haemolysin XhlA UPRTase PF14681.6 KXT07066.1 - 1.5e-75 253.2 0.0 1.6e-75 253.1 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KXT07066.1 - 1.9e-07 30.8 0.1 4.6e-07 29.5 0.1 1.6 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyl_synth PF14572.6 KXT07066.1 - 0.047 13.7 0.0 0.068 13.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl synthetase-associated domain CAP_GLY PF01302.25 KXT07067.1 - 2.4e-26 91.5 0.2 3.5e-26 91.0 0.2 1.2 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 KXT07067.1 - 3e-15 56.5 0.0 4.5e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 KXT07067.1 - 0.00011 21.9 0.0 0.00021 20.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Abhydrolase_1 PF00561.20 KXT07068.1 - 1.7e-06 27.9 0.2 3.9e-06 26.7 0.2 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KXT07068.1 - 3e-06 28.0 0.4 4.7e-06 27.4 0.4 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF5399 PF17377.2 KXT07068.1 - 0.065 13.0 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5399) TRAPPC9-Trs120 PF08626.11 KXT07073.1 - 7.5e-194 646.4 0.0 1e-190 636.0 0.0 2.8 2 1 0 2 2 2 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit VTC PF09359.10 KXT07073.1 - 3.9e-92 308.5 0.9 3.9e-92 308.5 0.9 1.5 2 0 0 2 2 2 1 VTC domain Glyco_hydro_61 PF03443.14 KXT07073.1 - 8.9e-65 218.5 0.0 1.9e-64 217.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF202 PF02656.15 KXT07073.1 - 3.2e-14 53.1 1.6 1.3e-13 51.1 1.6 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF202) SPX PF03105.19 KXT07073.1 - 0.00096 19.2 1.0 0.00096 19.2 1.0 4.7 4 1 1 5 5 5 2 SPX domain AA_permease PF00324.21 KXT07075.1 - 8.3e-05 21.4 5.2 0.00011 20.9 5.2 1.1 1 0 0 1 1 1 1 Amino acid permease TMEM238 PF15125.6 KXT07075.1 - 0.027 14.7 1.9 0.038 14.2 0.2 1.9 1 1 0 2 2 2 0 TMEM238 protein family Abp2 PF09441.10 KXT07076.1 - 2.8e-80 268.4 0.0 4.6e-80 267.7 0.0 1.3 1 0 0 1 1 1 1 ARS binding protein 2 ARID PF01388.21 KXT07076.1 - 0.095 13.4 0.0 0.24 12.1 0.0 1.6 1 0 0 1 1 1 0 ARID/BRIGHT DNA binding domain PX PF00787.24 KXT07077.1 - 4.7e-17 62.0 0.1 9.7e-17 61.0 0.1 1.6 1 0 0 1 1 1 1 PX domain Tmemb_cc2 PF10267.9 KXT07077.1 - 0.0048 16.1 1.4 0.0048 16.1 1.4 2.1 1 1 1 2 2 2 1 Predicted transmembrane and coiled-coil 2 protein Prefoldin_3 PF13758.6 KXT07077.1 - 0.016 15.3 1.6 0.02 14.9 0.3 1.9 2 0 0 2 2 2 0 Prefoldin subunit Nucleoporin_FG PF13634.6 KXT07077.1 - 0.073 13.9 21.4 0.68 10.8 1.6 2.5 2 0 0 2 2 2 0 Nucleoporin FG repeat region DUF3552 PF12072.8 KXT07077.1 - 1 8.7 5.5 1.7 8.0 5.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF4094 PF13334.6 KXT07078.1 - 0.85 10.1 0.0 0.85 10.1 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4094) ALMS_motif PF15309.6 KXT07079.1 - 0.36 11.3 4.0 14 6.1 4.0 3.0 1 1 0 1 1 1 0 ALMS motif UreD PF01774.17 KXT07080.1 - 2.6e-70 236.7 0.0 3.1e-70 236.4 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein DUF5313 PF17240.2 KXT07081.1 - 0.21 12.1 1.0 0.38 11.2 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5313) Cullin_binding PF03556.15 KXT07082.1 - 7.2e-33 113.6 9.1 1.4e-32 112.7 9.1 1.4 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.6 KXT07082.1 - 6e-13 48.4 0.1 1.3e-12 47.3 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain DSBA PF01323.20 KXT07083.1 - 8e-30 104.1 0.0 9e-30 103.9 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 KXT07083.1 - 4.6e-07 30.1 0.6 7.2e-06 26.3 0.0 2.1 1 1 0 2 2 2 1 Thioredoxin Thioredoxin_3 PF13192.6 KXT07083.1 - 0.059 13.4 0.0 1.1 9.4 0.0 2.4 2 1 0 2 2 2 0 Thioredoxin domain HrpJ PF07201.11 KXT07083.1 - 0.063 13.6 0.3 0.099 13.0 0.3 1.3 1 0 0 1 1 1 0 HrpJ-like domain VIT1 PF01988.19 KXT07084.1 - 0.18 11.7 0.5 0.26 11.1 0.5 1.2 1 0 0 1 1 1 0 VIT family TMIE PF16038.5 KXT07084.1 - 1.7 8.6 3.7 3.1 7.7 3.4 1.5 1 1 1 2 2 2 0 TMIE protein DUF1772 PF08592.11 KXT07085.1 - 2.6e-17 63.4 2.0 4.6e-17 62.6 0.3 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF1772) Bestrophin PF01062.21 KXT07086.1 - 4.3e-56 190.5 0.0 5.2e-56 190.2 0.0 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel F-box PF00646.33 KXT07087.1 - 1.5e-07 31.1 1.2 2.9e-07 30.2 0.1 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KXT07087.1 - 2.3e-05 24.2 1.1 5.2e-05 23.1 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 KXT07087.1 - 0.0019 18.1 0.0 0.0082 16.0 0.0 2.1 1 0 0 1 1 1 1 F-box ketoacyl-synt PF00109.26 KXT07088.1 - 7e-71 238.8 0.0 1.6e-70 237.6 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 KXT07088.1 - 3.5e-45 154.6 6.5 5e-45 154.1 0.1 3.0 2 1 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 KXT07088.1 - 7.4e-38 130.8 0.1 1.4e-37 129.9 0.1 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KXT07088.1 - 8.2e-36 122.6 0.1 2.2e-35 121.2 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.20 KXT07088.1 - 5.2e-23 82.4 0.1 1.9e-22 80.6 0.0 2.1 2 0 0 2 2 2 1 Thioesterase domain PS-DH PF14765.6 KXT07088.1 - 2.5e-10 40.1 0.1 5.4e-10 39.0 0.1 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.25 KXT07088.1 - 7.8e-09 35.8 0.2 2.3e-08 34.3 0.2 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 KXT07088.1 - 0.014 14.7 1.0 0.036 13.4 0.1 2.0 2 0 0 2 2 2 0 Thiolase, N-terminal domain Cyclase PF04199.13 KXT07089.1 - 5.3e-32 110.9 0.0 7.4e-32 110.4 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Cyclase PF04199.13 KXT07090.1 - 5.3e-32 110.9 0.0 7.4e-32 110.4 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Cyclase PF04199.13 KXT07091.1 - 5.3e-32 110.9 0.0 7.4e-32 110.4 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Sugar_tr PF00083.24 KXT07092.1 - 1.5e-88 297.7 28.1 1.7e-51 175.5 8.8 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KXT07092.1 - 3.7e-25 88.6 45.8 2.4e-22 79.3 26.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Smr PF01713.21 KXT07092.1 - 0.097 13.0 0.0 3.3 8.1 0.0 2.8 3 0 0 3 3 3 0 Smr domain Herpes_LMP1 PF05297.11 KXT07092.1 - 0.27 10.4 2.9 0.24 10.6 1.1 1.7 1 1 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) ABC2_membrane_2 PF12679.7 KXT07092.1 - 6.2 6.0 12.2 0.59 9.4 5.6 2.7 3 0 0 3 3 3 0 ABC-2 family transporter protein Sugar_tr PF00083.24 KXT07093.1 - 7.4e-91 305.3 25.9 1.8e-51 175.5 8.8 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KXT07093.1 - 2.9e-24 85.6 48.8 2.9e-21 75.8 28.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Smr PF01713.21 KXT07093.1 - 0.1 13.0 0.0 3.4 8.1 0.0 2.8 3 0 0 3 3 3 0 Smr domain ABC2_membrane_2 PF12679.7 KXT07093.1 - 5.9 6.1 12.0 0.61 9.3 5.6 2.6 3 0 0 3 3 3 0 ABC-2 family transporter protein CENP-X PF09415.10 KXT07094.1 - 3.7e-05 23.9 0.2 8.7e-05 22.8 0.2 1.6 1 0 0 1 1 1 1 CENP-S associating Centromere protein X TFIIF_alpha PF05793.12 KXT07094.1 - 1.1 7.7 8.6 1.4 7.4 8.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SWIRM-assoc_2 PF16496.5 KXT07094.1 - 4.3 6.1 9.4 5 5.9 9.4 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal MFS_1 PF07690.16 KXT07096.1 - 1.2e-33 116.5 52.0 6.4e-33 114.1 49.4 3.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXT07096.1 - 5.8e-10 38.2 13.7 8.5e-10 37.7 13.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) zf-LITAF-like PF10601.9 KXT07096.1 - 1.7 8.9 3.6 5.9 7.2 0.2 3.6 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain Endomucin PF07010.12 KXT07096.1 - 2.4 8.1 14.5 4.4 7.2 14.5 1.4 1 0 0 1 1 1 0 Endomucin Presenilin PF01080.17 KXT07096.1 - 3.3 6.4 7.4 0.11 11.2 1.3 1.7 2 0 0 2 2 2 0 Presenilin GREB1 PF15782.5 KXT07096.1 - 7.1 3.6 7.4 9.4 3.2 7.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SURF1 PF02104.15 KXT07098.1 - 9.5e-43 146.5 0.0 1.4e-42 145.9 0.0 1.2 1 0 0 1 1 1 1 SURF1 family Mobilization_B PF17511.2 KXT07099.1 - 0.18 12.2 0.3 0.18 12.2 0.3 1.8 2 0 0 2 2 2 0 Mobilization protein B Mif2_N PF15624.6 KXT07101.1 - 4.7e-33 114.8 4.1 4.7e-33 114.8 4.1 4.3 3 1 1 4 4 4 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal CENP-C_C PF11699.8 KXT07101.1 - 5.2e-27 93.9 0.8 9.7e-27 93.0 0.8 1.5 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.11 KXT07101.1 - 0.0022 17.7 0.4 0.0059 16.3 0.0 2.0 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 KXT07101.1 - 0.015 14.9 0.2 0.027 14.1 0.2 1.3 1 0 0 1 1 1 0 Cupin Cupin_6 PF12852.7 KXT07101.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Cupin ANAPC4_WD40 PF12894.7 KXT07102.1 - 8.9e-16 58.0 0.0 6.4e-06 26.4 0.0 5.3 3 1 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXT07102.1 - 1.7e-07 31.8 4.7 0.078 13.9 0.0 5.9 6 0 0 6 6 6 2 WD domain, G-beta repeat PD40 PF07676.12 KXT07102.1 - 5.6e-07 29.3 0.1 0.018 15.0 0.1 4.5 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat IKI3 PF04762.12 KXT07102.1 - 1.1e-05 23.7 0.0 0.13 10.2 0.0 2.9 2 1 1 3 3 3 3 IKI3 family eIF2A PF08662.11 KXT07102.1 - 0.0004 20.3 0.0 0.062 13.2 0.0 3.1 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Proteasome_A_N PF10584.9 KXT07102.1 - 0.00073 19.2 3.2 6.7 6.5 0.0 4.3 4 0 0 4 4 4 2 Proteasome subunit A N-terminal signature DUF485 PF04341.12 KXT07103.1 - 4.3 7.4 14.3 0.13 12.3 1.8 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF485 Mito_carr PF00153.27 KXT07104.1 - 5e-61 202.7 2.2 2.5e-20 72.2 0.1 3.5 2 2 1 3 3 3 3 Mitochondrial carrier protein PPR_2 PF13041.6 KXT07105.1 - 6.2e-20 71.1 0.1 3.4e-08 33.5 0.0 5.2 4 1 1 5 5 5 4 PPR repeat family PPR_3 PF13812.6 KXT07105.1 - 6.1e-10 39.0 0.1 8.1e-06 25.8 0.0 3.2 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR PF01535.20 KXT07105.1 - 7.4e-07 29.0 4.4 0.0056 16.8 0.0 4.7 5 0 0 5 5 5 2 PPR repeat PPR_1 PF12854.7 KXT07105.1 - 0.00032 20.4 0.0 0.022 14.5 0.0 3.7 5 0 0 5 5 5 1 PPR repeat PPR_long PF17177.4 KXT07105.1 - 0.015 14.6 0.0 0.57 9.5 0.0 2.8 3 0 0 3 3 3 0 Pentacotripeptide-repeat region of PRORP FlgN PF05130.12 KXT07105.1 - 0.049 14.1 1.2 14 6.2 0.1 2.9 2 0 0 2 2 2 0 FlgN protein Nha1_C PF08619.10 KXT07106.1 - 1.3e-96 324.7 56.3 2e-96 324.1 56.3 1.2 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.21 KXT07106.1 - 1.3e-79 267.8 21.1 1.5e-79 267.5 21.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF4190 PF13828.6 KXT07106.1 - 0.93 9.3 5.2 2.6 7.9 0.0 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4190) YrhC PF14143.6 KXT07106.1 - 1.8 8.7 3.2 1.5 9.0 0.4 2.2 2 0 0 2 2 2 0 YrhC-like protein DUF21 PF01595.20 KXT07106.1 - 2.7 7.7 6.2 0.79 9.4 2.0 2.2 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain HATPase_c PF02518.26 KXT07107.1 - 7.7e-21 74.7 0.0 1.8e-20 73.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KXT07107.1 - 1.5e-18 67.0 0.1 7e-15 55.2 0.1 2.8 3 0 0 3 3 3 2 Response regulator receiver domain HisKA PF00512.25 KXT07107.1 - 2.5e-11 43.4 0.0 5.8e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain ABC_tran PF00005.27 KXT07108.1 - 3.3e-46 157.2 1.0 1.8e-23 83.6 0.0 4.1 3 2 0 3 3 2 2 ABC transporter 4HB PF17947.1 KXT07108.1 - 9.5e-29 99.3 3.3 1e-28 99.2 0.4 2.5 2 0 0 2 2 2 1 Four helical bundle domain AAA_21 PF13304.6 KXT07108.1 - 5.7e-16 59.2 0.1 0.0024 17.7 0.0 4.5 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXT07108.1 - 3.4e-15 56.1 0.0 1.4e-05 24.6 0.0 3.9 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KXT07108.1 - 1e-07 31.6 0.1 0.014 15.1 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.6 KXT07108.1 - 6.6e-07 29.7 0.0 0.063 13.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KXT07108.1 - 2.3e-06 27.6 0.4 0.0031 17.4 0.0 3.0 3 0 0 3 3 2 1 RsgA GTPase AAA_23 PF13476.6 KXT07108.1 - 2.8e-06 28.0 17.2 0.0077 16.8 0.0 3.8 3 1 0 3 3 2 2 AAA domain AAA_22 PF13401.6 KXT07108.1 - 3.7e-06 27.2 0.6 0.11 12.8 0.0 4.0 5 0 0 5 5 3 2 AAA domain PduV-EutP PF10662.9 KXT07108.1 - 4.6e-06 26.4 0.1 0.15 11.8 0.0 3.1 3 0 0 3 3 2 2 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 KXT07108.1 - 6.8e-06 26.2 0.0 0.0071 16.4 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA PF00004.29 KXT07108.1 - 7.8e-06 26.3 0.1 0.13 12.6 0.0 4.3 4 1 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KXT07108.1 - 1.2e-05 25.8 0.5 0.28 11.5 0.0 3.8 5 0 0 5 5 2 2 AAA ATPase domain AAA_18 PF13238.6 KXT07108.1 - 6.5e-05 23.5 0.1 0.75 10.3 0.0 3.0 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 KXT07108.1 - 0.00017 21.6 0.1 0.17 11.8 0.0 2.9 3 0 0 3 3 2 1 NACHT domain G-alpha PF00503.20 KXT07108.1 - 0.00021 20.6 0.3 0.77 8.8 0.0 3.2 3 0 0 3 3 3 2 G-protein alpha subunit RNA_helicase PF00910.22 KXT07108.1 - 0.00022 21.6 0.0 0.66 10.4 0.0 2.8 2 0 0 2 2 2 1 RNA helicase DUF87 PF01935.17 KXT07108.1 - 0.00033 20.8 1.8 0.15 12.1 0.0 3.6 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_24 PF13479.6 KXT07108.1 - 0.00043 20.1 0.0 1.5 8.5 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_27 PF13514.6 KXT07108.1 - 0.00056 19.6 0.1 0.36 10.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain HEAT_2 PF13646.6 KXT07108.1 - 0.00069 20.0 0.1 0.17 12.3 0.1 2.9 1 1 1 2 2 2 1 HEAT repeats AAA_30 PF13604.6 KXT07108.1 - 0.00073 19.3 0.0 0.86 9.3 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 KXT07108.1 - 0.00081 19.4 0.0 1.5 8.9 0.0 3.3 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.6 KXT07108.1 - 0.001 19.2 0.0 2.2 8.5 0.0 3.2 2 0 0 2 2 2 1 AAA domain DUF3385 PF11865.8 KXT07108.1 - 0.0017 18.3 1.5 0.17 11.8 0.3 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF3385) DRIM PF07539.12 KXT07108.1 - 0.0018 16.7 3.3 0.068 11.5 0.6 2.4 1 1 1 2 2 2 1 Down-regulated in metastasis Roc PF08477.13 KXT07108.1 - 0.0019 18.4 0.2 2.9 8.1 0.0 3.1 3 0 0 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 KXT07108.1 - 0.0021 17.7 0.2 1.9 8.1 0.0 3.4 4 0 0 4 4 3 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 KXT07108.1 - 0.0022 17.0 0.1 0.51 9.3 0.0 2.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ATPase_2 PF01637.18 KXT07108.1 - 0.0038 17.2 0.1 1.3 8.8 0.0 3.5 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea ATP_bind_1 PF03029.17 KXT07108.1 - 0.0044 16.8 0.0 3.7 7.2 0.0 2.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.22 KXT07108.1 - 0.0047 16.2 0.8 0.22 10.7 0.0 2.8 3 0 0 3 3 3 1 NB-ARC domain Dynamin_N PF00350.23 KXT07108.1 - 0.0051 16.9 2.2 0.013 15.6 0.0 2.8 3 1 0 3 3 2 1 Dynamin family HEAT PF02985.22 KXT07108.1 - 0.0056 16.8 2.0 2.9 8.4 0.0 4.2 4 0 0 4 4 3 1 HEAT repeat Vac14_Fab1_bd PF12755.7 KXT07108.1 - 0.0078 16.8 0.1 4.2 8.0 0.0 3.5 2 1 1 3 3 2 0 Vacuolar 14 Fab1-binding region MMS19_C PF12460.8 KXT07108.1 - 0.009 15.2 0.5 3.4 6.7 0.2 3.1 2 1 0 2 2 2 0 RNAPII transcription regulator C-terminal T2SSE PF00437.20 KXT07108.1 - 0.011 14.8 0.0 3.9 6.4 0.0 2.7 2 0 0 2 2 2 0 Type II/IV secretion system protein SbcCD_C PF13558.6 KXT07108.1 - 0.011 15.9 0.0 2 8.7 0.0 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ATP-synt_ab PF00006.25 KXT07108.1 - 0.015 14.9 0.0 3 7.4 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Septin PF00735.18 KXT07108.1 - 0.021 14.1 0.5 3.3 6.9 0.0 3.2 3 0 0 3 3 3 0 Septin IstB_IS21 PF01695.17 KXT07108.1 - 0.022 14.5 0.0 9.5 5.9 0.0 3.0 2 0 0 2 2 2 0 IstB-like ATP binding protein TsaE PF02367.17 KXT07108.1 - 0.036 14.1 0.0 7.3 6.6 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 KXT07108.1 - 0.042 13.4 0.0 7.7 6.0 0.0 3.0 3 0 0 3 3 2 0 AAA domain Ecm29 PF13001.7 KXT07108.1 - 0.051 12.2 0.6 0.12 11.0 0.5 1.6 1 1 1 2 2 2 0 Proteasome stabiliser RuvB_N PF05496.12 KXT07108.1 - 0.052 13.3 0.4 4.9 6.9 0.0 2.9 3 0 0 3 3 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 KXT07108.1 - 0.055 13.0 0.0 8.3 5.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 KXT07108.1 - 0.065 12.6 0.0 6.7 6.0 0.0 2.9 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 KXT07108.1 - 0.066 13.1 0.0 3.9 7.4 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_5 PF07728.14 KXT07108.1 - 0.08 12.9 0.0 15 5.6 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 KXT07108.1 - 0.08 12.8 0.2 16 5.3 0.1 2.8 2 0 0 2 2 2 0 NTPase Arf PF00025.21 KXT07108.1 - 0.081 12.4 0.0 15 5.0 0.0 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family CLP1_P PF16575.5 KXT07108.1 - 0.091 12.6 4.0 0.89 9.3 0.0 3.4 5 0 0 5 5 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_15 PF13175.6 KXT07108.1 - 0.11 12.2 13.1 0.67 9.6 0.0 4.3 5 1 0 6 6 4 0 AAA ATPase domain MukB PF04310.12 KXT07108.1 - 0.12 12.2 0.0 25 4.6 0.0 2.8 2 0 0 2 2 2 0 MukB N-terminal AAA_13 PF13166.6 KXT07108.1 - 0.28 9.8 14.6 0.49 9.0 0.0 5.2 5 1 1 6 6 6 0 AAA domain FYVE PF01363.21 KXT07109.1 - 2.2e-15 56.6 10.8 4.3e-15 55.6 9.2 1.9 1 1 1 2 2 2 2 FYVE zinc finger Sugar_tr PF00083.24 KXT07110.1 - 4.3e-111 372.0 18.3 5.2e-111 371.7 18.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXT07110.1 - 4e-20 72.1 40.6 7.7e-16 58.0 14.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily EF1G PF00647.19 KXT07112.1 - 4e-46 155.5 0.3 8.4e-46 154.4 0.3 1.6 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 KXT07112.1 - 2.7e-15 56.3 3.4 2.1e-14 53.5 0.0 2.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KXT07112.1 - 7.3e-13 48.7 0.1 7.3e-12 45.5 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KXT07112.1 - 9.3e-07 29.2 0.0 1.9e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KXT07112.1 - 3.5e-06 26.9 0.1 9e-06 25.6 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KXT07112.1 - 0.0006 20.0 0.1 0.0017 18.5 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KXT07112.1 - 0.0058 16.9 0.0 0.014 15.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Myb_DNA-binding PF00249.31 KXT07114.1 - 1.2e-14 54.2 3.8 1.2e-10 41.4 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KXT07114.1 - 2.3e-08 34.2 6.7 4.5e-05 23.6 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain TruD PF01142.18 KXT07115.1 - 2.3e-55 188.1 0.3 1.5e-50 172.2 0.2 3.8 3 2 0 3 3 3 3 tRNA pseudouridine synthase D (TruD) IHABP4_N PF16174.5 KXT07115.1 - 0.017 15.7 6.2 0.017 15.7 6.2 2.2 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal RR_TM4-6 PF06459.12 KXT07115.1 - 2.5 7.9 6.3 7 6.4 6.3 1.7 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3328 PF11807.8 KXT07118.1 - 3.2e-51 174.2 0.0 4.4e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) NKAP PF15692.5 KXT07119.1 - 0.049 14.4 0.8 0.085 13.6 0.8 1.3 1 0 0 1 1 1 0 NF-kappa-B-activating protein RHD3 PF05879.12 KXT07120.1 - 0 1021.1 0.0 0 1020.9 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 KXT07120.1 - 6.9e-09 35.3 0.1 1.2e-08 34.6 0.1 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 KXT07120.1 - 2.1e-05 24.7 0.0 4.3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KXT07120.1 - 0.00011 22.3 0.0 0.00024 21.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 KXT07120.1 - 0.0081 15.5 0.1 0.015 14.6 0.1 1.4 1 0 0 1 1 1 1 Septin AAA_28 PF13521.6 KXT07120.1 - 0.018 15.3 0.3 0.089 13.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Phi_1 PF04674.12 KXT07120.1 - 0.13 11.6 0.3 0.22 10.8 0.3 1.3 1 0 0 1 1 1 0 Phosphate-induced protein 1 conserved region Glyco_hydro_67M PF07488.12 KXT07121.1 - 3.2e-143 476.7 0.1 5.4e-143 475.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.12 KXT07121.1 - 2.3e-86 288.9 2.8 3.4e-86 288.4 2.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.14 KXT07121.1 - 4.3e-28 98.1 0.0 1.1e-27 96.7 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 67 N-terminus Glyco_hydro_20b PF02838.15 KXT07121.1 - 0.00042 21.1 0.1 0.0011 19.7 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 DUF4838 PF16126.5 KXT07121.1 - 0.13 11.6 0.0 1.3 8.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4838) zf-C3HC4_2 PF13923.6 KXT07122.1 - 2.9e-08 33.4 4.9 4.5e-07 29.6 2.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KXT07122.1 - 9.2e-08 32.0 2.3 9.2e-08 32.0 2.3 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KXT07122.1 - 2e-07 30.8 7.4 3.5e-07 30.0 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXT07122.1 - 7.3e-07 29.4 7.8 1.7e-05 25.0 8.3 2.2 1 1 1 2 2 2 2 Ring finger domain zf-RING_5 PF14634.6 KXT07122.1 - 7.4e-07 29.0 4.0 1.7e-06 27.9 4.0 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KXT07122.1 - 1e-05 25.2 6.0 2.3e-05 24.2 6.0 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KXT07122.1 - 2.7e-05 24.2 4.9 0.00015 21.8 5.4 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KXT07122.1 - 0.0084 15.9 9.0 0.05 13.5 8.9 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-Nse PF11789.8 KXT07122.1 - 0.01 15.7 3.1 0.019 14.8 3.1 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 KXT07122.1 - 0.068 13.3 1.5 0.17 12.1 1.5 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 KXT07122.1 - 0.27 11.3 2.0 0.59 10.2 2.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 KXT07122.1 - 0.28 11.0 6.5 2.1 8.2 3.9 2.6 2 0 0 2 2 2 0 RING-like zinc finger FYVE PF01363.21 KXT07122.1 - 0.37 11.0 1.9 0.84 9.8 1.9 1.6 1 0 0 1 1 1 0 FYVE zinc finger zf-rbx1 PF12678.7 KXT07122.1 - 3.6 7.9 7.3 12 6.2 7.3 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-MIZ PF02891.20 KXT07122.1 - 9.2 6.1 9.5 58 3.5 9.3 2.2 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger YjeF_N PF03853.15 KXT07123.1 - 1.2e-23 83.8 0.1 1.9e-23 83.2 0.1 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 KXT07123.1 - 1.2e-07 32.6 1.4 1.2e-07 32.6 1.4 2.1 2 0 0 2 2 2 1 FDF domain LSM PF01423.22 KXT07123.1 - 0.0048 16.6 0.1 0.01 15.5 0.1 1.5 1 0 0 1 1 1 1 LSM domain Arginase PF00491.21 KXT07123.1 - 0.0081 15.7 0.2 0.031 13.8 0.0 1.9 2 0 0 2 2 2 1 Arginase family SM-ATX PF14438.6 KXT07123.1 - 0.035 14.2 0.0 0.11 12.7 0.0 1.9 1 0 0 1 1 1 0 Ataxin 2 SM domain YjeF_N PF03853.15 KXT07124.1 - 2.6e-10 40.5 0.1 4.4e-10 39.7 0.1 1.4 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 KXT07124.1 - 7.7e-08 33.2 1.2 7.7e-08 33.2 1.2 2.2 2 0 0 2 2 2 1 FDF domain LSM PF01423.22 KXT07124.1 - 0.0039 16.9 0.1 0.008 15.8 0.1 1.5 1 0 0 1 1 1 1 LSM domain Arginase PF00491.21 KXT07124.1 - 0.0058 16.2 0.2 0.026 14.0 0.0 1.9 2 0 0 2 2 2 1 Arginase family SM-ATX PF14438.6 KXT07124.1 - 0.033 14.3 0.0 0.084 13.0 0.0 1.7 1 0 0 1 1 1 0 Ataxin 2 SM domain FAD_binding_4 PF01565.23 KXT07125.1 - 6.2e-25 87.5 3.0 9.4e-25 87.0 3.0 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KXT07125.1 - 0.081 13.0 0.2 0.18 11.9 0.2 1.6 1 0 0 1 1 1 0 Berberine and berberine like PEX11 PF05648.14 KXT07126.1 - 2.5e-14 53.3 0.0 9.4e-14 51.4 0.0 1.9 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) RGS PF00615.19 KXT07127.1 - 0.13 12.5 0.4 8.6 6.7 0.0 2.2 2 0 0 2 2 2 0 Regulator of G protein signaling domain Toxin_ToxA PF11584.8 KXT07127.1 - 0.14 12.2 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Proteinaceous host-selective toxin ToxA Choline_transpo PF04515.12 KXT07128.1 - 1.7e-28 99.8 18.4 1.7e-28 99.8 18.4 2.6 2 2 0 2 2 2 1 Plasma-membrane choline transporter PAN_4 PF14295.6 KXT07128.1 - 0.00014 21.7 0.4 0.0003 20.6 0.4 1.6 1 0 0 1 1 1 1 PAN domain Velvet PF11754.8 KXT07129.1 - 3.8e-52 177.7 0.0 7e-35 121.2 0.0 4.6 1 1 2 3 3 3 2 Velvet factor Rap_GAP PF02145.15 KXT07130.1 - 4.5e-45 153.5 0.0 7.5e-45 152.8 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 KXT07130.1 - 3.3e-24 85.7 2.3 3e-21 75.9 0.1 2.5 2 0 0 2 2 2 2 Tuberin DUF3384 PF11864.8 KXT07130.1 - 1e-13 51.0 0.9 1.4e-13 50.6 0.2 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3384) Corona_7 PF02398.16 KXT07130.1 - 0.02 15.5 0.2 0.047 14.3 0.2 1.5 1 0 0 1 1 1 0 Coronavirus protein 7 Fungal_trans PF04082.18 KXT07131.1 - 1.1e-22 80.4 0.1 2.7e-22 79.1 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT07131.1 - 1.4e-07 31.5 9.6 2.4e-07 30.7 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1995 PF09353.10 KXT07132.1 - 0.0074 16.3 13.1 21 5.1 4.1 5.5 1 1 2 3 3 3 1 Domain of unknown function (DUF1995) DUF5347 PF17282.2 KXT07132.1 - 0.012 15.9 4.3 9.5 6.6 0.1 4.7 1 1 4 5 5 5 0 Family of unknown function (DUF5347) DUF5078 PF16877.5 KXT07132.1 - 0.039 14.4 10.7 3.8 8.0 1.1 3.6 1 1 3 4 4 4 0 Domain of unknown function (DUF5078) FaeA PF04703.12 KXT07132.1 - 0.041 14.3 21.7 49 4.4 0.1 6.8 1 1 6 7 7 7 0 FaeA-like protein TMEM252 PF15664.5 KXT07132.1 - 0.049 13.4 17.3 0.81 9.4 5.1 3.1 1 1 2 3 3 3 0 Transmembrane protein 252 family DUF3106 PF11304.8 KXT07132.1 - 0.65 10.5 10.2 5.4 7.5 1.2 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3106) Il2rg PF15874.5 KXT07132.1 - 8.9 6.7 9.7 1.1e+02 3.2 0.2 3.8 1 1 4 5 5 5 0 Putative Interleukin 2 receptor, gamma chain DUF3192 PF11399.8 KXT07132.1 - 9.1 6.3 10.9 42 4.2 0.2 3.5 1 1 5 6 6 6 0 Protein of unknown function (DUF3192) NMT1 PF09084.11 KXT07133.1 - 1.4e-39 136.2 0.0 1.8e-39 135.9 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 KXT07133.1 - 6.4e-06 26.0 0.0 3.9e-05 23.5 0.0 2.1 1 1 1 3 3 3 1 NMT1-like family 4HBT PF03061.22 KXT07134.1 - 1.2e-09 38.4 0.0 1.6e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 KXT07134.1 - 0.017 15.4 0.0 0.021 15.1 0.0 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily DUF4442 PF14539.6 KXT07134.1 - 0.06 13.5 0.0 0.064 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) 4HBT PF03061.22 KXT07135.1 - 1.3e-09 38.2 0.0 1.8e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 KXT07135.1 - 0.019 15.3 0.0 0.023 14.9 0.0 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily adh_short PF00106.25 KXT07138.1 - 3.2e-16 59.4 0.4 3.7e-16 59.2 0.4 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT07138.1 - 4.5e-08 32.9 0.1 5.7e-08 32.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT07138.1 - 0.038 13.9 0.1 0.046 13.6 0.1 1.1 1 0 0 1 1 1 0 KR domain NmrA PF05368.13 KXT07138.1 - 0.14 11.7 0.5 0.18 11.3 0.5 1.1 1 0 0 1 1 1 0 NmrA-like family NAD_binding_2 PF03446.15 KXT07140.1 - 6.1e-34 117.5 0.1 9.2e-34 116.9 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KXT07140.1 - 2.7e-22 79.3 0.0 4.5e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.19 KXT07140.1 - 0.031 13.6 0.0 0.054 12.9 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF656 PF04920.12 KXT07140.1 - 0.035 14.0 0.1 0.4 10.6 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF656) IlvN PF07991.12 KXT07140.1 - 0.13 11.8 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain MFS_1 PF07690.16 KXT07143.1 - 6e-40 137.2 35.7 6e-40 137.2 35.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KXT07143.1 - 6.1e-12 45.1 14.2 6.1e-12 45.1 14.2 2.6 2 1 0 3 3 3 1 Sugar (and other) transporter DUF1129 PF06570.11 KXT07143.1 - 0.056 12.9 5.0 0.034 13.6 1.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) DUF4538 PF15061.6 KXT07143.1 - 0.22 11.3 1.5 1.4 8.7 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) DUF3817 PF12823.7 KXT07143.1 - 2.5 9.0 9.9 0.18 12.7 1.5 3.4 3 2 1 4 4 4 0 Domain of unknown function (DUF3817) DUF3328 PF11807.8 KXT07144.1 - 4.8e-31 108.2 0.7 1.6e-30 106.5 0.7 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) ERG4_ERG24 PF01222.17 KXT07145.1 - 9.1e-93 311.3 8.0 1.1e-92 311.1 8.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KXT07145.1 - 0.0065 16.0 0.2 0.016 14.7 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.17 KXT07146.1 - 9.7e-65 219.0 4.7 1.2e-64 218.7 4.7 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF872 PF05915.12 KXT07146.1 - 1.5 9.0 4.9 11 6.3 0.3 3.5 4 0 0 4 4 4 0 Eukaryotic protein of unknown function (DUF872) Eaf7 PF07904.13 KXT07147.1 - 2.2e-22 79.4 0.0 2.2e-22 79.4 0.0 2.2 2 1 0 2 2 2 1 Chromatin modification-related protein EAF7 Raftlin PF15250.6 KXT07147.1 - 2.2 6.9 4.4 3.2 6.4 4.4 1.2 1 0 0 1 1 1 0 Raftlin DDRGK PF09756.9 KXT07147.1 - 4.7 6.8 10.8 8.1 6.0 10.8 1.3 1 0 0 1 1 1 0 DDRGK domain NPR3 PF03666.13 KXT07147.1 - 9.5 4.9 7.3 15 4.2 7.3 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 TFIIA PF03153.13 KXT07149.1 - 0.0092 16.0 16.5 0.014 15.4 16.5 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Spc7 PF08317.11 KXT07149.1 - 0.018 13.9 25.1 0.48 9.2 10.1 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein COG2 PF06148.11 KXT07149.1 - 0.28 11.2 8.7 2.8 8.0 0.3 2.5 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 FlaC_arch PF05377.11 KXT07149.1 - 0.57 10.6 5.7 47 4.5 1.0 4.2 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF1319 PF07028.11 KXT07149.1 - 0.81 9.9 5.0 0.86 9.8 0.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1319) Baculo_PEP_C PF04513.12 KXT07149.1 - 1.4 8.9 16.4 2.6 8.1 12.6 2.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TolA_bind_tri PF16331.5 KXT07149.1 - 1.9 8.6 7.4 12 6.1 0.8 2.7 2 0 0 2 2 2 0 TolA binding protein trimerisation TMF_TATA_bd PF12325.8 KXT07149.1 - 3.6 7.8 21.2 0.15 12.3 3.2 3.5 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Prefoldin_2 PF01920.20 KXT07149.1 - 4.8 7.2 19.5 2.6 8.0 9.8 3.3 2 1 0 2 2 2 0 Prefoldin subunit YojJ PF10372.9 KXT07149.1 - 5.1 7.3 5.7 16 5.7 0.7 2.7 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus FapA PF03961.13 KXT07149.1 - 7 5.1 12.1 25 3.3 12.1 1.8 1 1 0 1 1 1 0 Flagellar Assembly Protein A FAD_binding_3 PF01494.19 KXT07150.1 - 1.5e-13 50.8 2.4 0.00033 20.0 0.8 3.1 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.6 KXT07150.1 - 0.0075 16.5 0.7 0.021 15.0 0.7 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KXT07150.1 - 0.039 13.2 0.2 0.062 12.5 0.2 1.2 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 KXT07150.1 - 0.051 12.6 1.2 0.092 11.8 1.2 1.4 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KXT07150.1 - 0.081 11.6 0.7 0.12 11.0 0.7 1.2 1 0 0 1 1 1 0 HI0933-like protein p450 PF00067.22 KXT07151.1 - 2.2e-52 178.3 0.1 5.3e-52 177.1 0.1 1.5 1 1 0 1 1 1 1 Cytochrome P450 FMN_dh PF01070.18 KXT07152.1 - 2e-107 359.2 0.0 2.4e-107 359.0 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KXT07152.1 - 1.8e-19 69.7 0.0 3.1e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KXT07152.1 - 0.0001 21.6 0.0 0.00018 20.8 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KXT07152.1 - 0.00077 18.6 0.1 0.012 14.6 0.0 2.4 2 1 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KXT07153.1 - 2e-107 359.2 0.0 2.4e-107 359.0 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KXT07153.1 - 1.8e-19 69.7 0.0 3.1e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KXT07153.1 - 0.0001 21.6 0.0 0.00018 20.8 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KXT07153.1 - 0.00077 18.6 0.1 0.012 14.6 0.0 2.4 2 1 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain Atg14 PF10186.9 KXT07156.1 - 7.3e-18 64.7 15.3 1.5e-17 63.7 12.8 2.4 2 1 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 KXT07156.1 - 3.9e-10 39.2 0.7 2.5e-08 33.2 0.4 2.7 2 1 0 2 2 2 1 Vacuolar protein sorting 38 APG6 PF04111.12 KXT07156.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Apg6 BARA domain TetR_C_2 PF08361.11 KXT07156.1 - 0.16 12.1 0.8 0.42 10.7 0.7 1.8 1 1 0 1 1 1 0 MAATS-type transcriptional repressor, C-terminal region BAR_2 PF10455.9 KXT07156.1 - 0.41 9.7 6.1 0.82 8.8 6.1 1.4 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF4407 PF14362.6 KXT07156.1 - 0.92 8.8 8.1 1.8 7.9 8.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 KXT07156.1 - 3.4 6.5 14.3 6.2 5.6 14.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Methyltransf_2 PF00891.18 KXT07157.1 - 3.2e-23 82.1 0.0 4.9e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Rrf2 PF02082.20 KXT07157.1 - 0.0024 18.2 0.0 0.0054 17.0 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulator Dimerisation PF08100.11 KXT07157.1 - 0.019 15.0 0.1 0.13 12.4 0.1 2.6 2 0 0 2 2 2 0 Dimerisation domain Peptidase_M24 PF00557.24 KXT07158.1 - 4.1e-21 75.6 0.0 4.9e-21 75.4 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 Aminotran_1_2 PF00155.21 KXT07159.1 - 2.1e-58 198.3 0.0 2.5e-58 198.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Neuropep_like PF15161.6 KXT07160.1 - 0.18 11.5 0.6 7.1 6.4 0.0 3.3 4 0 0 4 4 4 0 Neuropeptide-like Hpr_kinase_N PF02603.16 KXT07161.1 - 0.087 12.8 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase N terminus UBM PF14377.6 KXT07161.1 - 0.13 11.8 1.7 2.4 7.7 0.2 2.7 2 0 0 2 2 2 0 Ubiquitin binding region Slu7 PF11708.8 KXT07162.1 - 1.8e-71 241.0 20.1 1.8e-71 241.0 20.1 3.2 2 1 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor Glyco_hydro_11 PF00457.17 KXT07163.1 - 0.25 10.9 1.6 0.32 10.6 1.6 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 11 Hydrolase PF00702.26 KXT07164.1 - 8.8e-07 29.4 0.0 3e-06 27.7 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KXT07164.1 - 0.00013 22.1 0.0 0.00017 21.7 0.0 1.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Fis1_TPR_C PF14853.6 KXT07165.1 - 2.4e-25 88.3 0.9 3.8e-25 87.7 0.9 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 KXT07165.1 - 1.7e-16 59.6 0.2 3.5e-16 58.6 0.2 1.6 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 KXT07165.1 - 0.0004 20.3 1.6 0.00088 19.2 1.6 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 KXT07165.1 - 0.021 15.3 0.4 0.068 13.7 0.2 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KXT07165.1 - 0.025 14.4 3.0 0.053 13.4 3.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 KXT07165.1 - 0.033 14.8 0.1 0.085 13.5 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat EF-hand_1 PF00036.32 KXT07166.1 - 5.7e-27 91.2 12.4 2.6e-07 29.7 0.5 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KXT07166.1 - 1.2e-23 83.3 14.0 2.4e-14 53.5 1.5 2.8 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KXT07166.1 - 1.3e-20 71.5 6.0 4.6e-05 23.0 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KXT07166.1 - 4.3e-18 63.9 9.8 2.2e-06 26.9 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KXT07166.1 - 6.2e-13 48.4 12.6 0.00016 21.5 0.8 4.2 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KXT07166.1 - 1.5e-06 28.5 0.1 0.0035 17.6 0.1 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KXT07166.1 - 6.2e-06 26.1 8.2 0.0026 17.7 0.5 3.9 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 KXT07166.1 - 0.071 13.3 0.6 0.29 11.4 0.5 2.2 1 1 0 1 1 1 0 Dockerin type I domain EF-hand_9 PF14658.6 KXT07166.1 - 0.089 13.1 0.2 2.4 8.6 0.1 2.8 2 1 1 3 3 3 0 EF-hand domain mono-CXXC PF15626.6 KXT07167.1 - 0.16 12.4 0.1 0.27 11.6 0.1 1.3 1 0 0 1 1 1 0 single CXXC unit TIG PF01833.24 KXT07168.1 - 5.4e-11 42.4 3.6 4.1e-10 39.6 2.6 2.7 2 0 0 2 2 2 1 IPT/TIG domain RHD_dimer PF16179.5 KXT07168.1 - 0.002 18.1 0.1 0.041 13.9 0.0 3.0 3 0 0 3 3 3 1 Rel homology dimerisation domain DAO PF01266.24 KXT07169.1 - 2.5e-43 149.0 0.0 3.2e-43 148.7 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KXT07169.1 - 8e-05 22.0 0.1 0.0032 16.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXT07169.1 - 0.0018 17.5 1.6 0.41 9.8 0.6 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXT07169.1 - 0.0021 16.8 0.1 0.058 12.1 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.6 KXT07169.1 - 0.0048 16.9 1.7 0.36 10.8 0.0 2.9 4 0 0 4 4 4 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KXT07169.1 - 0.0077 15.3 0.0 0.15 11.1 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein K_oxygenase PF13434.6 KXT07169.1 - 0.013 14.7 0.0 0.038 13.1 0.0 1.6 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KXT07169.1 - 0.064 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Malic_M PF03949.15 KXT07169.1 - 0.12 11.6 0.0 0.28 10.4 0.0 1.6 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain CRCB PF02537.15 KXT07170.1 - 1.6e-34 118.1 17.6 1.4e-21 76.5 9.0 2.7 2 1 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) Prion_bPrPp PF11587.8 KXT07170.1 - 3.3 7.6 5.5 1.1 9.1 1.8 2.1 2 0 0 2 2 2 0 Major prion protein bPrPp - N terminal Cu-oxidase_2 PF07731.14 KXT07171.1 - 6.8e-39 132.7 0.6 5.5e-38 129.8 0.0 2.3 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 KXT07171.1 - 2.1e-32 112.4 1.5 3.4e-31 108.5 0.2 3.0 2 1 1 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 KXT07171.1 - 2.3e-29 101.8 9.9 6e-28 97.2 6.1 3.4 3 1 0 3 3 3 1 Multicopper oxidase Ribosomal_S9 PF00380.19 KXT07172.1 - 7.3e-42 142.7 0.2 1.1e-41 142.1 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 CTU2 PF10288.9 KXT07173.1 - 3.6e-12 46.5 0.1 3.6e-12 46.5 0.1 3.1 2 1 1 3 3 3 2 Cytoplasmic tRNA 2-thiolation protein 2 PutA_N PF18083.1 KXT07173.1 - 0.054 13.5 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Proline utilization A N-terminal domain zf-AD PF07776.15 KXT07173.1 - 1.4 9.2 8.7 0.52 10.6 0.5 3.1 2 1 1 3 3 3 0 Zinc-finger associated domain (zf-AD) DUF1770 PF08589.10 KXT07174.1 - 1.5e-29 102.8 0.8 2e-29 102.4 0.8 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) MMS1_N PF10433.9 KXT07175.1 - 3.3e-105 352.5 0.0 4.1e-105 352.2 0.0 1.1 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KXT07175.1 - 1.4e-89 300.6 0.0 5.8e-89 298.6 0.0 2.0 3 0 0 3 3 3 1 CPSF A subunit region EST1_DNA_bind PF10373.9 KXT07176.1 - 5.1e-52 177.1 0.0 7.9e-52 176.5 0.0 1.3 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 KXT07176.1 - 1e-13 52.1 0.0 3.1e-13 50.5 0.0 1.8 1 0 0 1 1 1 1 Telomerase activating protein Est1 NAD_binding_2 PF03446.15 KXT07177.1 - 2.6e-27 95.9 0.1 3.8e-27 95.4 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KXT07177.1 - 6.8e-27 94.1 0.1 1.1e-26 93.5 0.1 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KXT07177.1 - 0.00088 19.8 0.1 0.0021 18.6 0.0 1.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KXT07177.1 - 0.0013 18.2 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Rossmann-like PF10727.9 KXT07177.1 - 0.0079 16.0 0.1 0.019 14.8 0.1 1.6 1 0 0 1 1 1 1 Rossmann-like domain UDPG_MGDP_dh_N PF03721.14 KXT07177.1 - 0.03 13.9 0.0 0.42 10.2 0.0 2.2 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 KXT07177.1 - 0.044 14.1 0.0 0.089 13.0 0.0 1.6 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 KXT07177.1 - 0.094 12.6 0.0 0.34 10.8 0.0 1.9 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GMC_oxred_N PF00732.19 KXT07178.1 - 2.3e-40 138.8 0.8 4.1e-40 138.0 0.8 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KXT07178.1 - 4e-27 95.5 0.0 8.8e-27 94.4 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KXT07178.1 - 1.4e-06 27.7 0.3 3.3e-06 26.4 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KXT07178.1 - 9.1e-06 25.1 0.2 1.9e-05 24.1 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KXT07178.1 - 1.1e-05 24.8 0.1 2.5e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 KXT07178.1 - 1.3e-05 24.6 0.0 2.1e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KXT07178.1 - 2.8e-05 24.2 1.3 0.0018 18.5 0.6 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KXT07178.1 - 0.0067 15.8 1.6 0.012 15.0 1.6 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 KXT07178.1 - 0.0083 15.7 9.3 0.084 12.4 9.3 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KXT07178.1 - 0.037 13.1 0.1 0.06 12.4 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 KXT07178.1 - 0.057 12.1 0.2 0.083 11.6 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein ThiF PF00899.21 KXT07178.1 - 0.06 12.7 0.2 0.15 11.4 0.0 1.6 2 0 0 2 2 2 0 ThiF family Pyr_redox PF00070.27 KXT07178.1 - 0.063 13.9 0.1 0.14 12.7 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KXT07178.1 - 0.18 10.8 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.14 KXT07178.1 - 0.22 11.1 1.6 0.34 10.5 1.6 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_31 PF13847.6 KXT07180.1 - 6e-16 58.6 0.0 8.6e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXT07180.1 - 3.8e-15 56.4 0.0 2.6e-14 53.7 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXT07180.1 - 4.4e-14 52.9 0.0 5.6e-13 49.4 0.0 2.4 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXT07180.1 - 4.8e-14 52.9 0.0 8.2e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KXT07180.1 - 2.1e-12 47.2 0.0 3.4e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXT07180.1 - 1.2e-07 31.3 0.0 2.2e-06 27.2 0.0 2.6 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 KXT07180.1 - 0.00011 22.2 0.0 0.00017 21.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KXT07180.1 - 0.00023 20.7 0.0 0.00051 19.5 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.19 KXT07180.1 - 0.00029 20.6 0.0 0.00076 19.3 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KXT07180.1 - 0.00056 19.5 0.0 0.0013 18.3 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain RrnaAD PF00398.20 KXT07180.1 - 0.001 18.2 0.0 0.0014 17.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase CMAS PF02353.20 KXT07180.1 - 0.025 13.9 0.0 2.5 7.3 0.0 2.1 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase MetW PF07021.12 KXT07180.1 - 0.03 13.9 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW NNMT_PNMT_TEMT PF01234.17 KXT07180.1 - 0.032 13.4 0.0 2 7.6 0.0 2.8 3 0 0 3 3 3 0 NNMT/PNMT/TEMT family FtsJ PF01728.19 KXT07180.1 - 0.036 14.2 0.0 0.19 11.9 0.0 2.0 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltr_RsmB-F PF01189.17 KXT07180.1 - 0.049 13.3 0.0 0.1 12.3 0.0 1.5 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F DREV PF05219.12 KXT07180.1 - 0.11 11.6 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_5 PF01795.19 KXT07180.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 MraW methylase family Peptidase_S10 PF00450.22 KXT07182.1 - 5.8e-125 418.0 0.1 8e-125 417.5 0.1 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.11 KXT07182.1 - 7.3e-16 58.8 1.7 1.4e-15 58.0 1.7 1.4 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide GCV_T PF01571.21 KXT07184.1 - 3.4e-66 223.3 0.0 5.4e-66 222.6 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DAO PF01266.24 KXT07184.1 - 3.9e-49 168.1 0.2 7.8e-49 167.1 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase MoaC PF01967.21 KXT07184.1 - 1e-47 161.6 2.4 2.1e-47 160.6 2.4 1.6 1 0 0 1 1 1 1 MoaC family FAO_M PF16350.5 KXT07184.1 - 7.8e-18 64.6 0.0 2.1e-17 63.2 0.0 1.8 1 0 0 1 1 1 1 FAD dependent oxidoreductase central domain GCV_T_C PF08669.11 KXT07184.1 - 1.7e-15 56.7 0.1 4.7e-15 55.3 0.1 1.8 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Pyr_redox PF00070.27 KXT07184.1 - 2.2e-05 24.9 0.0 0.015 15.8 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KXT07184.1 - 2.7e-05 23.6 0.0 0.03 13.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXT07184.1 - 5.3e-05 23.4 0.0 0.075 13.3 0.0 3.0 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KXT07184.1 - 0.00051 19.3 0.2 0.0016 17.6 0.2 1.8 1 1 0 1 1 1 1 FAD binding domain SoxG PF04268.12 KXT07184.1 - 0.0026 17.9 0.0 0.01 16.0 0.0 1.9 2 0 0 2 2 2 1 Sarcosine oxidase, gamma subunit family TrkA_N PF02254.18 KXT07184.1 - 0.0032 17.7 0.1 0.0089 16.3 0.1 1.8 2 0 0 2 2 1 1 TrkA-N domain Trp_halogenase PF04820.14 KXT07184.1 - 0.0097 14.8 1.0 0.081 11.8 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase FAD_binding_3 PF01494.19 KXT07184.1 - 0.021 14.1 0.9 0.69 9.1 0.5 2.3 2 0 0 2 2 2 0 FAD binding domain ThiF PF00899.21 KXT07184.1 - 0.025 13.9 0.3 0.063 12.6 0.0 1.7 2 0 0 2 2 2 0 ThiF family NAD_binding_9 PF13454.6 KXT07184.1 - 0.059 13.4 0.2 3.7 7.5 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding Shikimate_DH PF01488.20 KXT07184.1 - 0.061 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 KXT07184.1 - 0.15 10.7 0.2 1.4 7.6 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein CAP PF00188.26 KXT07185.1 - 3e-19 70.1 2.6 4.1e-19 69.6 2.6 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 KXT07186.1 - 8.3e-18 65.4 3.0 8.4e-17 62.2 3.0 2.0 1 1 0 1 1 1 1 Cysteine-rich secretory protein family Thioredoxin PF00085.20 KXT07187.1 - 4.2e-58 193.7 0.1 4.5e-29 100.5 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 KXT07187.1 - 9.5e-20 71.3 1.3 2.1e-19 70.2 0.6 2.1 2 0 0 2 2 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain OST3_OST6 PF04756.13 KXT07187.1 - 7.4e-17 61.6 0.0 1.2e-07 31.4 0.0 2.3 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 KXT07187.1 - 2.3e-14 53.8 0.1 1.1e-05 25.8 0.0 2.9 2 0 0 2 2 2 2 Thioredoxin-like domain HET PF06985.11 KXT07187.1 - 1.3e-11 45.0 10.8 1.3e-10 41.8 3.7 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 KXT07187.1 - 1.3e-11 44.0 5.6 2.1e-11 43.4 5.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Thioredoxin_8 PF13905.6 KXT07187.1 - 1.7e-06 28.3 0.0 0.019 15.3 0.0 4.0 2 2 1 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 KXT07187.1 - 3.4e-06 27.0 0.1 0.01 15.7 0.0 2.8 2 0 0 2 2 2 2 AhpC/TSA family TraF PF13728.6 KXT07187.1 - 3.7e-06 26.9 0.0 0.011 15.6 0.0 2.4 2 0 0 2 2 2 2 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 KXT07187.1 - 2e-05 24.7 0.0 0.32 11.2 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.6 KXT07187.1 - 6.6e-05 22.7 0.0 0.023 14.5 0.0 2.6 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_6 PF13848.6 KXT07187.1 - 0.001 19.0 0.0 1.9 8.3 0.0 3.2 2 1 0 2 2 2 1 Thioredoxin-like domain Glutaredoxin PF00462.24 KXT07187.1 - 0.012 15.8 0.3 5.5 7.3 0.2 3.2 2 1 0 2 2 2 0 Glutaredoxin Redoxin PF08534.10 KXT07187.1 - 0.025 14.3 0.1 5.7 6.6 0.0 2.5 2 0 0 2 2 2 0 Redoxin HyaE PF07449.11 KXT07187.1 - 0.039 13.9 0.0 13 5.8 0.0 2.9 3 0 0 3 3 3 0 Hydrogenase-1 expression protein HyaE F-box PF00646.33 KXT07188.1 - 1.7e-05 24.6 0.0 3.4e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KXT07188.1 - 0.00012 21.9 0.1 0.00024 20.9 0.1 1.5 1 0 0 1 1 1 1 F-box-like Toxin_31 PF08119.11 KXT07189.1 - 0.0062 16.3 0.9 0.015 15.0 0.9 1.6 1 0 0 1 1 1 1 Scorpion acidic alpha-KTx toxin family BTB PF00651.31 KXT07189.1 - 0.0066 16.7 0.0 0.013 15.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Ribosomal_S14 PF00253.21 KXT07190.1 - 5.5e-20 70.9 1.9 5.5e-20 70.9 1.9 1.6 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e Toxin_31 PF08119.11 KXT07191.1 - 0.0062 16.3 0.9 0.015 15.0 0.9 1.6 1 0 0 1 1 1 1 Scorpion acidic alpha-KTx toxin family BTB PF00651.31 KXT07191.1 - 0.0066 16.7 0.0 0.013 15.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Ribosomal_S14 PF00253.21 KXT07192.1 - 5.5e-20 70.9 1.9 5.5e-20 70.9 1.9 1.6 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e Toxin_31 PF08119.11 KXT07193.1 - 0.0062 16.3 0.9 0.015 15.0 0.9 1.6 1 0 0 1 1 1 1 Scorpion acidic alpha-KTx toxin family BTB PF00651.31 KXT07193.1 - 0.0066 16.7 0.0 0.013 15.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Ribosomal_S14 PF00253.21 KXT07194.1 - 5.5e-20 70.9 1.9 5.5e-20 70.9 1.9 1.6 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e Toxin_31 PF08119.11 KXT07195.1 - 0.0062 16.3 0.9 0.015 15.0 0.9 1.6 1 0 0 1 1 1 1 Scorpion acidic alpha-KTx toxin family BTB PF00651.31 KXT07195.1 - 0.0066 16.7 0.0 0.013 15.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain MFS_1 PF07690.16 KXT07196.1 - 5.4e-24 84.8 28.4 5.4e-24 84.8 28.4 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXT07196.1 - 4.3e-06 25.9 18.8 7.2e-06 25.1 17.3 2.1 1 1 1 2 2 2 1 Sugar (and other) transporter TraL PF07178.11 KXT07196.1 - 4.8 7.7 10.4 0.82 10.2 0.6 3.4 3 1 1 4 4 4 0 TraL protein MFS_1 PF07690.16 KXT07197.1 - 5.4e-24 84.8 28.4 5.4e-24 84.8 28.4 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXT07197.1 - 4.3e-06 25.9 18.8 7.2e-06 25.1 17.3 2.1 1 1 1 2 2 2 1 Sugar (and other) transporter TraL PF07178.11 KXT07197.1 - 4.8 7.7 10.4 0.82 10.2 0.6 3.4 3 1 1 4 4 4 0 TraL protein EthD PF07110.11 KXT07198.1 - 0.0058 17.7 0.1 0.023 15.8 0.1 1.9 1 1 0 1 1 1 1 EthD domain NCBP3 PF10309.9 KXT07198.1 - 0.18 11.6 1.0 2.2 8.2 0.1 2.6 2 1 1 3 3 3 0 Nuclear cap-binding protein subunit 3 Ribosomal_S14 PF00253.21 KXT07199.1 - 5.5e-20 70.9 1.9 5.5e-20 70.9 1.9 1.6 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e SUR7 PF06687.12 KXT07200.1 - 1.5e-26 93.3 4.1 2.2e-26 92.8 4.1 1.1 1 0 0 1 1 1 1 SUR7/PalI family Pox_P21 PF05313.12 KXT07200.1 - 0.013 15.1 0.1 0.013 15.1 0.1 1.5 2 0 0 2 2 2 0 Poxvirus P21 membrane protein DFP PF04127.15 KXT07201.1 - 1.1e-12 48.2 0.0 6.2e-05 22.9 0.0 3.2 2 1 0 3 3 3 3 DNA / pantothenate metabolism flavoprotein Zn_clus PF00172.18 KXT07202.1 - 1.6 8.9 12.3 4.1 7.6 12.3 1.7 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain NARP1 PF12569.8 KXT07204.1 - 1.6 7.6 25.6 2.8 6.7 25.6 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 NARP1 PF12569.8 KXT07205.1 - 1.6 7.6 25.6 2.8 6.7 25.6 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Sugar_tr PF00083.24 KXT07207.1 - 1.6e-89 300.9 27.9 1.9e-89 300.7 27.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXT07207.1 - 7.8e-16 57.9 43.9 1.1e-10 41.0 21.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KXT07207.1 - 0.00057 18.4 3.4 0.0011 17.5 3.4 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DLH PF01738.18 KXT07209.1 - 2.2e-25 89.5 0.0 2.9e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Chlorophyllase2 PF12740.7 KXT07209.1 - 0.006 15.5 0.0 0.0081 15.1 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KXT07209.1 - 0.086 11.8 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase LIDHydrolase PF10230.9 KXT07209.1 - 0.1 12.2 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Peptidase_S15 PF02129.18 KXT07209.1 - 0.18 11.4 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.11 KXT07209.1 - 0.21 11.5 0.0 0.8 9.6 0.0 1.7 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal zf-H2C2_2 PF13465.6 KXT07211.1 - 9.2e-06 25.9 1.5 9.2e-06 25.9 1.5 2.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 KXT07211.1 - 0.00041 20.6 4.0 0.092 13.2 0.9 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXT07211.1 - 1.1 10.3 9.0 0.67 11.0 1.4 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXT07212.1 - 1.4e-05 25.3 1.5 1.4e-05 25.3 1.5 2.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 KXT07212.1 - 0.011 16.2 8.3 0.14 12.7 0.9 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-Mss51 PF13824.6 KXT07214.1 - 2.3e-27 94.8 5.5 4.3e-27 94.0 5.5 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 KXT07214.1 - 0.88 9.7 3.0 0.88 9.7 0.4 2.1 2 0 0 2 2 2 0 MYND finger IBR PF01485.21 KXT07215.1 - 1.1e-06 28.8 3.2 1.3e-06 28.5 3.2 1.1 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain zf-CRD PF17979.1 KXT07215.1 - 0.041 14.0 2.4 0.043 13.9 2.4 1.2 1 0 0 1 1 1 0 Cysteine rich domain with multizinc binding regions zf-C2H2 PF00096.26 KXT07215.1 - 0.47 11.0 4.4 5.1 7.8 0.4 2.4 2 1 0 2 2 2 0 Zinc finger, C2H2 type Peptidase_M24 PF00557.24 KXT07216.1 - 1.2e-51 175.3 0.0 2.4e-51 174.4 0.0 1.5 1 1 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KXT07216.1 - 1.7e-23 82.7 0.0 3.1e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain His_binding PF02098.16 KXT07218.1 - 0.067 13.2 0.0 0.087 12.9 0.0 1.1 1 0 0 1 1 1 0 Tick histamine binding protein Isochorismatase PF00857.20 KXT07219.1 - 2.9e-26 92.7 0.0 2e-25 90.0 0.0 2.0 1 1 0 1 1 1 1 Isochorismatase family NAD_binding_10 PF13460.6 KXT07221.1 - 9.1e-36 123.5 0.6 1.1e-35 123.1 0.6 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KXT07221.1 - 4e-11 42.8 0.0 1.1e-10 41.3 0.0 1.6 1 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KXT07221.1 - 2.8e-06 27.1 0.1 0.00022 20.9 0.0 2.3 2 0 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.12 KXT07221.1 - 0.0013 18.0 0.0 0.0022 17.2 0.0 1.5 2 0 0 2 2 2 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KXT07221.1 - 0.0018 17.7 0.0 0.0029 17.1 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KXT07221.1 - 0.0064 15.6 0.0 0.011 14.9 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain Ligase_CoA PF00549.19 KXT07221.1 - 0.035 13.9 0.4 0.035 13.9 0.4 1.8 2 0 0 2 2 2 0 CoA-ligase DUF5585 PF17823.1 KXT07221.1 - 0.042 12.8 0.4 0.055 12.4 0.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5585) Polyketide_cyc2 PF10604.9 KXT07223.1 - 6.4e-08 33.0 0.1 7.5e-08 32.8 0.1 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport SH3_4 PF06347.13 KXT07223.1 - 0.1 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain LSM PF01423.22 KXT07224.1 - 1.1e-18 66.7 0.2 1.6e-18 66.2 0.2 1.3 1 0 0 1 1 1 1 LSM domain bZIP_1 PF00170.21 KXT07225.1 - 1e-08 35.1 8.2 1e-08 35.1 8.2 2.2 2 1 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KXT07225.1 - 0.001 19.1 10.4 0.001 19.1 10.4 2.7 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 KXT07225.1 - 0.0084 16.6 7.8 0.0084 16.6 7.8 2.8 2 0 0 2 2 2 1 bZIP Maf transcription factor SQS_PSY PF00494.19 KXT07226.1 - 5.1e-51 173.7 0.1 7.3e-51 173.2 0.1 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase Methyltransf_2 PF00891.18 KXT07227.1 - 1.1e-20 73.8 0.0 2e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 KXT07227.1 - 0.0062 17.2 0.0 0.017 15.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain DUF4942 PF13708.6 KXT07228.1 - 0.045 13.7 0.0 0.09 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4942) MIP PF00230.20 KXT07229.1 - 8.6e-38 130.3 16.4 1.1e-37 130.0 16.4 1.1 1 0 0 1 1 1 1 Major intrinsic protein Abhydrolase_4 PF08386.10 KXT07230.1 - 9.6e-19 67.4 0.0 2.1e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 KXT07230.1 - 1.7e-14 54.1 0.0 2e-06 27.6 0.0 3.0 3 0 0 3 3 3 2 alpha/beta hydrolase fold Fungal_trans PF04082.18 KXT07231.1 - 1.7e-27 96.1 1.1 2.3e-27 95.7 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT07231.1 - 5.4e-07 29.6 9.9 9e-07 28.9 9.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MHC_I_C PF06623.11 KXT07231.1 - 0.27 11.2 1.9 0.8 9.7 1.9 1.8 1 0 0 1 1 1 0 MHC_I C-terminus TLP1_add_C PF18313.1 KXT07232.1 - 1e-26 92.7 0.0 2.4e-26 91.5 0.0 1.6 1 0 0 1 1 1 1 Thiolase-like protein type 1 additional C-terminal domain Glyco_hydro_64 PF16483.5 KXT07233.1 - 5.7e-116 387.8 0.1 1.1e-115 386.9 0.0 1.5 2 0 0 2 2 2 1 Beta-1,3-glucanase E1-E2_ATPase PF00122.20 KXT07234.1 - 1.5e-34 119.1 1.5 1.5e-34 119.1 1.5 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KXT07234.1 - 7.2e-34 117.1 7.4 7.2e-34 117.1 7.4 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KXT07234.1 - 1.1e-18 68.3 1.9 2.5e-18 67.2 1.9 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KXT07234.1 - 4.2e-17 62.0 0.0 9.2e-17 60.9 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KXT07234.1 - 1.8e-10 40.3 0.6 7.2e-09 35.2 0.1 2.6 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KXT07234.1 - 0.00016 21.5 0.3 0.0014 18.4 0.2 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Polyketide_cyc PF03364.20 KXT07236.1 - 0.0003 21.0 0.1 0.00049 20.3 0.1 1.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 KXT07236.1 - 0.00073 19.8 0.3 0.0039 17.4 0.0 2.0 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport Sulfotransfer_3 PF13469.6 KXT07237.1 - 0.004 17.6 0.6 0.14 12.5 0.1 3.0 2 1 0 2 2 2 1 Sulfotransferase family VIT1 PF01988.19 KXT07238.1 - 0.0043 17.0 0.0 0.005 16.7 0.0 1.2 1 0 0 1 1 1 1 VIT family CitMHS PF03600.16 KXT07238.1 - 0.03 13.5 0.1 0.037 13.2 0.1 1.1 1 0 0 1 1 1 0 Citrate transporter CLPTM1 PF05602.12 KXT07239.1 - 2.4e-150 501.3 0.0 2.9e-150 501.0 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) His_Phos_2 PF00328.22 KXT07246.1 - 3.1e-20 72.9 0.0 6.5e-20 71.8 0.0 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Helicase_C PF00271.31 KXT07247.1 - 1.2e-17 64.2 0.0 2e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KXT07247.1 - 0.00015 21.1 0.1 0.00017 20.9 0.1 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase RRM_1 PF00076.22 KXT07248.1 - 4.8e-11 42.3 0.0 8.3e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Borrelia_P83 PF05262.11 KXT07248.1 - 9 4.7 12.9 14 4.0 12.9 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein PKD_channel PF08016.12 KXT07249.1 - 1.4e-05 24.0 16.3 0.00038 19.3 16.3 2.1 1 1 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 KXT07249.1 - 7.4e-05 22.1 25.4 0.00063 19.0 25.4 2.0 1 1 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 KXT07250.1 - 0.041 14.2 0.0 0.082 13.3 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain ketoacyl-synt PF00109.26 KXT07251.1 - 4.1e-73 246.1 0.0 1e-72 244.8 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 KXT07251.1 - 4.4e-61 206.7 2.9 4.4e-61 206.7 2.9 2.5 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Ketoacyl-synt_C PF02801.22 KXT07251.1 - 9.5e-33 112.7 3.0 3.4e-32 110.9 3.0 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 KXT07251.1 - 2.6e-28 99.5 0.1 4.5e-28 98.7 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain Thioesterase PF00975.20 KXT07251.1 - 6.2e-26 91.9 0.1 1.8e-25 90.4 0.0 1.9 2 0 0 2 2 2 1 Thioesterase domain PS-DH PF14765.6 KXT07251.1 - 9.6e-17 61.2 0.0 1.7e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.25 KXT07251.1 - 2.7e-09 37.2 0.2 6.3e-09 36.1 0.2 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 KXT07251.1 - 2.8e-07 31.0 0.0 7.1e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 KXT07251.1 - 2.4e-05 23.8 0.6 9.1e-05 21.9 0.1 2.1 2 1 1 3 3 3 1 Thiolase, N-terminal domain Abhydrolase_6 PF12697.7 KXT07251.1 - 0.0011 19.6 9.8 0.0014 19.2 0.4 3.7 3 0 0 3 3 3 1 Alpha/beta hydrolase family ACP_syn_III PF08545.10 KXT07251.1 - 0.04 13.8 0.1 0.45 10.4 0.0 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GFO_IDH_MocA PF01408.22 KXT07252.1 - 1.7e-18 67.6 0.0 3.2e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KXT07252.1 - 7.3e-05 22.8 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain KRE1 PF17056.5 KXT07252.1 - 0.058 13.1 0.3 0.14 11.9 0.0 1.7 2 0 0 2 2 2 0 Killer toxin-resistance protein 1 Hydant_A_N PF05378.13 KXT07252.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region Cellulase PF00150.18 KXT07253.1 - 1.1e-19 71.0 4.6 1.7e-19 70.3 4.6 1.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 KXT07253.1 - 1.3e-07 31.1 0.1 1.1e-06 28.0 0.0 2.2 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.15 KXT07253.1 - 0.0021 17.4 0.1 0.0076 15.6 0.1 1.9 1 1 0 1 1 1 1 Beta-galactosidase Sugar_tr PF00083.24 KXT07254.1 - 7.8e-66 222.8 21.8 6.9e-64 216.4 21.8 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXT07254.1 - 2e-24 86.2 28.1 2e-24 86.2 28.1 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily BT1 PF03092.16 KXT07254.1 - 0.037 12.3 3.6 0.89 7.7 0.5 2.3 2 0 0 2 2 2 0 BT1 family PFU PF09070.11 KXT07256.1 - 0.015 15.6 0.0 0.028 14.7 0.0 1.4 1 0 0 1 1 1 0 PFU (PLAA family ubiquitin binding) FAM199X PF15814.5 KXT07256.1 - 0.15 11.1 1.8 0.36 9.8 1.8 1.6 1 0 0 1 1 1 0 Protein family FAM199X SBDS_C PF09377.10 KXT07257.1 - 7.1e-43 145.3 0.0 1.1e-42 144.8 0.0 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 KXT07257.1 - 4.4e-31 106.8 0.1 7.5e-31 106.1 0.1 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein PCI PF01399.27 KXT07258.1 - 3.5e-21 75.7 0.4 1.6e-20 73.6 0.0 2.3 2 1 1 3 3 3 1 PCI domain RPN5_C PF18098.1 KXT07258.1 - 7.6e-16 57.9 1.4 7.6e-16 57.9 1.4 2.0 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN5 C-terminal domain YfdX PF10938.8 KXT07258.1 - 0.37 10.7 7.0 0.18 11.7 0.6 3.2 4 0 0 4 4 4 0 YfdX protein Sugar_tr PF00083.24 KXT07259.1 - 2.3e-33 115.7 25.5 7.4e-17 61.3 7.4 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KXT07259.1 - 1.4e-25 90.0 38.7 6.7e-15 54.9 16.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KXT07259.1 - 0.0015 17.2 20.5 0.0027 16.3 5.4 2.9 1 1 2 3 3 3 3 MFS/sugar transport protein Phage_holin_2_4 PF16082.5 KXT07259.1 - 0.037 13.8 0.2 0.16 11.7 0.2 2.2 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like DUF2231 PF09990.9 KXT07259.1 - 0.85 10.1 8.5 0.43 11.1 3.8 2.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) Macro PF01661.21 KXT07261.1 - 6.4e-40 135.9 0.8 1.1e-39 135.2 0.2 1.7 2 0 0 2 2 2 1 Macro domain DUF637 PF04830.13 KXT07261.1 - 0.067 13.0 0.0 3.7 7.3 0.0 2.1 2 0 0 2 2 2 0 Possible hemagglutinin (DUF637) SKA1 PF07160.12 KXT07261.1 - 0.12 12.2 1.2 0.21 11.4 1.2 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Sigma70_r4_2 PF08281.12 KXT07262.1 - 0.00023 20.8 0.1 0.01 15.5 0.0 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 Recombinase PF07508.13 KXT07262.1 - 0.0079 16.6 0.1 0.7 10.3 0.0 2.5 2 1 1 3 3 3 1 Recombinase HTH_38 PF13936.6 KXT07262.1 - 0.06 13.1 0.6 3.3 7.6 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain DUF2437 PF10370.9 KXT07262.1 - 0.068 14.1 0.0 0.13 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2437) UbiA PF01040.18 KXT07264.1 - 2e-32 112.5 14.5 2.3e-32 112.3 14.1 1.3 1 1 0 1 1 1 1 UbiA prenyltransferase family CrgA PF06781.12 KXT07264.1 - 8.3e-05 22.6 1.6 0.0014 18.6 0.6 3.0 3 0 0 3 3 3 1 Cell division protein CrgA DUF2569 PF10754.9 KXT07264.1 - 0.21 12.0 6.2 0.39 11.2 2.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) FAD_binding_7 PF03441.14 KXT07265.1 - 4.7e-57 192.7 2.5 7.5e-57 192.1 2.5 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KXT07265.1 - 2.2e-41 141.6 0.0 4.3e-41 140.7 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase Caps_synth PF05704.12 KXT07266.1 - 3.2e-08 33.3 0.0 5.7e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.15 KXT07266.1 - 0.00046 20.8 0.0 0.0019 18.8 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Rhamno_transf PF11316.8 KXT07266.1 - 0.096 12.1 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative rhamnosyl transferase Acatn PF13000.7 KXT07267.1 - 4.6e-161 537.1 18.3 4.1e-81 273.2 8.9 3.1 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 Serglycin PF04360.12 KXT07267.1 - 0.039 13.9 1.1 0.07 13.1 0.6 1.6 1 1 0 1 1 1 0 Serglycin Ring_hydroxyl_A PF00848.19 KXT07268.1 - 5.7e-25 88.5 5.4 1.1e-11 45.1 0.1 2.2 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 KXT07268.1 - 5.9e-14 51.8 0.0 1.3e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain F-box-like PF12937.7 KXT07269.1 - 0.072 13.0 0.0 0.31 11.0 0.0 2.0 2 0 0 2 2 2 0 F-box-like Mob_synth_C PF06463.13 KXT07271.1 - 2.2e-37 127.8 0.1 2.4e-36 124.5 0.0 2.1 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 KXT07271.1 - 2.3e-18 67.1 0.0 4.2e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KXT07271.1 - 0.057 13.7 0.0 0.32 11.2 0.0 2.2 3 0 0 3 3 3 0 4Fe-4S single cluster domain RseC_MucC PF04246.12 KXT07272.1 - 0.039 13.9 0.3 0.039 13.9 0.3 2.1 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC BCS1_N PF08740.11 KXT07273.1 - 4e-37 128.0 0.4 8.4e-37 127.0 0.4 1.5 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KXT07273.1 - 4.8e-22 78.8 0.0 2.7e-21 76.4 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KXT07273.1 - 4.7e-07 29.7 0.0 8.4e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 KXT07273.1 - 0.00021 20.6 0.0 0.00037 19.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 KXT07273.1 - 0.00048 20.6 0.0 0.0017 18.8 0.0 1.9 2 1 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.22 KXT07273.1 - 0.016 15.6 0.0 0.048 14.0 0.0 1.8 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 KXT07273.1 - 0.023 14.8 0.0 0.049 13.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KXT07273.1 - 0.025 14.3 0.0 0.059 13.1 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 KXT07273.1 - 0.061 13.9 0.0 0.13 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KXT07273.1 - 0.066 13.6 0.2 3.1 8.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KXT07273.1 - 0.095 12.7 0.0 0.45 10.5 0.0 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) UpxZ PF06603.11 KXT07275.1 - 0.11 12.8 2.0 0.24 11.7 0.7 2.3 1 1 1 2 2 2 0 UpxZ family of transcription anti-terminator antagonists FAM184 PF15665.5 KXT07275.1 - 2.2 8.0 54.1 6 6.6 10.9 4.0 1 1 3 4 4 4 0 Family with sequence similarity 184, A and B Dak2 PF02734.17 KXT07276.1 - 0.012 15.6 0.9 0.049 13.5 1.1 1.8 1 1 1 2 2 2 0 DAK2 domain Thaumatin PF00314.17 KXT07278.1 - 6e-68 228.7 6.3 1.4e-67 227.5 6.3 1.6 1 1 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 KXT07278.1 - 0.043 13.1 1.7 0.083 12.2 0.0 2.1 2 0 0 2 2 2 0 Beta-1,3-glucanase Laminin_II PF06009.12 KXT07279.1 - 0.94 9.5 14.9 0.27 11.2 9.7 2.3 1 1 1 2 2 2 0 Laminin Domain II Nup88 PF10168.9 KXT07279.1 - 2 6.1 22.3 2.8 5.7 22.3 1.1 1 0 0 1 1 1 0 Nuclear pore component MIP-T3_C PF17749.1 KXT07279.1 - 4.9 7.1 15.9 1.1 9.2 7.4 2.9 2 1 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region I_LWEQ PF01608.17 KXT07279.1 - 4.9 7.4 18.4 5.3 7.3 13.0 3.0 2 1 1 3 3 3 0 I/LWEQ domain Phage_GPO PF05929.11 KXT07279.1 - 5.4 6.6 20.3 2.8 7.5 6.2 2.3 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Thioredoxin_8 PF13905.6 KXT07280.1 - 0.082 13.2 0.0 11 6.5 0.0 2.3 1 1 1 2 2 2 0 Thioredoxin-like STAG PF08514.11 KXT07283.1 - 2.5e-31 107.9 2.5 2.5e-31 107.9 2.5 3.2 4 0 0 4 4 4 1 STAG domain HEAT_2 PF13646.6 KXT07283.1 - 6.3e-08 32.9 0.3 0.0062 16.9 0.0 3.8 2 1 1 3 3 3 2 HEAT repeats YL1 PF05764.13 KXT07283.1 - 0.00059 20.0 12.0 0.00059 20.0 12.0 4.4 3 1 0 3 3 3 1 YL1 nuclear protein HEAT PF02985.22 KXT07283.1 - 0.00089 19.3 0.6 69 4.1 0.0 5.9 5 0 0 5 5 5 0 HEAT repeat Xpo1 PF08389.12 KXT07283.1 - 0.062 13.4 1.5 4.3 7.4 0.1 3.2 3 0 0 3 3 3 0 Exportin 1-like protein PalH PF08733.10 KXT07284.1 - 6.2e-118 393.6 0.0 7.6e-118 393.3 0.0 1.1 1 0 0 1 1 1 1 PalH/RIM21 GIIM PF08388.11 KXT07284.1 - 0.17 11.9 0.2 0.45 10.6 0.2 1.7 1 0 0 1 1 1 0 Group II intron, maturase-specific domain SUR7 PF06687.12 KXT07287.1 - 2.9e-31 108.8 4.1 3.6e-31 108.5 4.1 1.1 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 KXT07287.1 - 0.0062 16.5 6.9 0.0062 16.5 6.9 1.7 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 Deltameth_res PF16020.5 KXT07287.1 - 0.46 10.4 2.7 0.36 10.7 0.3 2.1 2 0 0 2 2 2 0 Deltamethrin resistance Mt_ATP-synt_B PF05405.14 KXT07288.1 - 1.1e-45 155.2 3.2 1.3e-45 154.9 3.2 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF349 PF03993.12 KXT07288.1 - 0.00035 20.8 0.3 0.73 10.2 1.9 2.7 2 0 0 2 2 2 2 Domain of Unknown Function (DUF349) T4_neck-protein PF11649.8 KXT07288.1 - 0.061 12.6 0.0 0.085 12.2 0.0 1.2 1 0 0 1 1 1 0 Virus neck protein Bromodomain PF00439.25 KXT07289.1 - 2e-06 27.8 0.0 8.4e-06 25.8 0.0 2.0 1 1 0 1 1 1 1 Bromodomain HSP70 PF00012.20 KXT07290.1 - 1.3e-262 872.4 11.8 1.5e-262 872.2 11.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KXT07290.1 - 3.7e-20 72.0 0.5 3.1e-19 69.0 0.2 2.0 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.10 KXT07290.1 - 0.026 13.5 0.2 0.33 9.9 0.2 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.16 KXT07290.1 - 0.095 12.4 0.0 0.67 9.6 0.0 2.2 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 KXT07290.1 - 0.69 9.1 4.9 0.89 8.7 0.2 2.8 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase CENP-Q PF13094.6 KXT07290.1 - 1.5 9.0 8.4 8.2 6.6 3.5 2.6 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit FtsA PF14450.6 KXT07290.1 - 6.6 7.2 10.9 28 5.2 0.4 3.8 3 2 0 3 3 3 0 Cell division protein FtsA HSP70 PF00012.20 KXT07291.1 - 1.3e-262 872.4 11.8 1.5e-262 872.2 11.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KXT07291.1 - 3.7e-20 72.0 0.5 3.1e-19 69.0 0.2 2.0 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.10 KXT07291.1 - 0.026 13.5 0.2 0.33 9.9 0.2 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.16 KXT07291.1 - 0.095 12.4 0.0 0.67 9.6 0.0 2.2 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 KXT07291.1 - 0.69 9.1 4.9 0.89 8.7 0.2 2.8 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase CENP-Q PF13094.6 KXT07291.1 - 1.5 9.0 8.4 8.2 6.6 3.5 2.6 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit FtsA PF14450.6 KXT07291.1 - 6.6 7.2 10.9 28 5.2 0.4 3.8 3 2 0 3 3 3 0 Cell division protein FtsA DUF4618 PF15397.6 KXT07292.1 - 0.016 14.7 1.2 0.021 14.2 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) DUF1737 PF08410.10 KXT07292.1 - 0.028 14.3 0.1 0.054 13.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1737) PRP1_N PF06424.12 KXT07292.1 - 0.03 14.7 2.5 0.038 14.4 2.5 1.2 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal CCDC-167 PF15188.6 KXT07292.1 - 0.13 12.6 1.3 0.23 11.8 1.3 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF4407 PF14362.6 KXT07292.1 - 0.23 10.8 3.3 0.31 10.4 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2681 PF10883.8 KXT07292.1 - 0.3 11.5 4.6 0.92 10.0 4.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) CBF PF03914.17 KXT07293.1 - 1.1e-32 113.4 1.5 1.4e-32 113.1 0.1 1.9 2 1 0 2 2 2 1 CBF/Mak21 family NOC3p PF07540.11 KXT07293.1 - 0.021 15.3 0.1 0.052 14.0 0.1 1.7 1 0 0 1 1 1 0 Nucleolar complex-associated protein Bt_P21 PF05560.11 KXT07293.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein NIBRIN_BRCT_II PF16508.5 KXT07295.1 - 2.7e-25 89.0 0.0 1.1e-24 87.1 0.0 2.1 1 0 0 1 1 1 1 Second BRCT domain on Nijmegen syndrome breakage protein zf-HIT PF04438.16 KXT07296.1 - 3.7e-11 42.7 11.6 6.5e-11 41.9 11.6 1.4 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 KXT07296.1 - 0.0042 17.1 15.1 0.0077 16.3 15.1 1.4 1 0 0 1 1 1 1 MYND finger zf-B_box PF00643.24 KXT07296.1 - 1.4 9.2 13.9 2.6 8.3 13.9 1.5 1 0 0 1 1 1 0 B-box zinc finger PolC_DP2 PF03833.13 KXT07296.1 - 3.3 5.5 7.1 4.2 5.1 7.1 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 MAT1 PF06391.13 KXT07298.1 - 3.1e-48 164.3 22.5 4.3e-48 163.9 22.5 1.2 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 KXT07298.1 - 6e-30 102.9 8.2 1.1e-29 102.1 8.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KXT07298.1 - 0.00089 19.1 5.8 0.0016 18.3 5.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KXT07298.1 - 0.001 19.0 6.2 0.0071 16.3 1.6 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KXT07298.1 - 0.0043 16.9 6.5 0.019 14.9 6.8 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KXT07298.1 - 0.0094 16.3 8.4 0.024 14.9 8.2 1.8 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KXT07298.1 - 0.012 15.4 7.3 0.069 13.0 7.5 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KXT07298.1 - 0.012 15.2 1.9 0.025 14.2 1.9 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DDHD PF02862.17 KXT07298.1 - 0.054 13.6 1.8 0.097 12.8 1.8 1.5 1 0 0 1 1 1 0 DDHD domain zf-RING_4 PF14570.6 KXT07298.1 - 0.074 12.9 4.8 0.93 9.3 2.5 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF3797 PF12677.7 KXT07298.1 - 0.34 10.8 1.8 0.75 9.7 1.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) HGTP_anticodon2 PF12745.7 KXT07298.1 - 1.5 8.3 11.6 2.5 7.5 11.6 1.3 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs LAP1C PF05609.12 KXT07298.1 - 1.6 7.7 14.5 2.3 7.2 14.5 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) zf-RING_UBOX PF13445.6 KXT07298.1 - 1.8 8.7 6.7 4.1 7.5 6.7 1.6 1 0 0 1 1 1 0 RING-type zinc-finger CTP_transf_like PF01467.26 KXT07299.1 - 1.2e-23 83.9 0.0 1.6e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like DUF5131 PF07505.11 KXT07299.1 - 0.019 14.4 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF5131) Cyt-b5 PF00173.28 KXT07300.1 - 4.9e-22 77.8 0.1 6.8e-22 77.4 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glyoxalase PF00903.25 KXT07301.1 - 3.7e-37 127.4 0.9 1.4e-17 64.1 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KXT07301.1 - 1.9e-20 73.1 0.2 2.8e-09 37.2 0.0 3.7 2 2 1 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KXT07301.1 - 3.1e-09 37.2 0.0 0.0007 19.8 0.0 2.6 1 1 1 2 2 2 2 Glyoxalase-like domain Glyoxalase_6 PF18029.1 KXT07301.1 - 4e-06 27.6 0.0 0.14 12.9 0.0 3.1 2 2 1 3 3 3 2 Glyoxalase-like domain Glyoxalase_2 PF12681.7 KXT07301.1 - 0.00073 19.4 2.4 11 6.0 0.0 4.3 4 1 1 5 5 5 2 Glyoxalase-like domain DUF1338 PF07063.13 KXT07301.1 - 0.00093 18.5 0.1 1.4 8.0 0.1 3.8 3 2 0 3 3 3 1 Domain of unknown function (DUF1338) CppA_N PF14506.6 KXT07301.1 - 0.0021 18.1 0.1 0.17 11.9 0.0 2.3 2 0 0 2 2 2 1 CppA N-terminal MoaF PF10703.9 KXT07301.1 - 0.021 14.7 0.1 3.3 7.7 0.0 2.6 2 0 0 2 2 2 0 MoaF N-terminal domain PRT_C PF08372.10 KXT07301.1 - 0.1 12.3 0.0 3.2 7.5 0.0 2.2 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal Acetyltransf_10 PF13673.7 KXT07301.1 - 0.14 12.1 0.8 0.45 10.5 0.2 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain 2-Hacid_dh_C PF02826.19 KXT07303.1 - 1.9e-54 183.7 1.2 3.5e-54 182.9 0.1 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KXT07303.1 - 1.5e-36 125.0 0.3 2.3e-36 124.4 0.3 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 KXT07303.1 - 0.0028 17.4 0.3 0.017 14.9 0.0 2.5 2 0 0 2 2 2 1 ACT domain AdoHcyase_NAD PF00670.21 KXT07303.1 - 0.0041 17.2 0.2 0.011 15.8 0.2 1.7 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.15 KXT07303.1 - 0.042 14.0 0.1 0.1 12.8 0.1 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase XdhC_C PF13478.6 KXT07303.1 - 0.048 14.2 0.1 0.32 11.5 0.0 2.4 3 0 0 3 3 3 0 XdhC Rossmann domain UDPG_MGDP_dh_C PF03720.15 KXT07303.1 - 0.099 13.1 0.0 0.34 11.3 0.0 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain FMN_dh PF01070.18 KXT07304.1 - 5.1e-130 433.6 0.0 5.9e-130 433.3 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KXT07304.1 - 2.9e-08 33.1 0.6 7e-08 31.9 0.3 1.7 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KXT07304.1 - 4.3e-06 26.1 0.1 9.3e-06 25.0 0.1 1.6 1 1 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 KXT07304.1 - 4.2e-05 23.1 1.6 7e-05 22.4 1.6 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 KXT07304.1 - 7.6e-05 22.3 0.1 0.00068 19.2 0.0 2.0 1 1 1 2 2 2 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 KXT07304.1 - 0.011 15.2 0.2 0.53 9.6 0.2 2.5 2 1 1 3 3 3 0 Ribulose-phosphate 3 epimerase family DHO_dh PF01180.21 KXT07304.1 - 0.03 13.5 0.1 0.096 11.9 0.0 1.8 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase ThiG PF05690.14 KXT07304.1 - 0.054 12.8 4.6 0.11 11.8 0.1 2.5 2 1 1 3 3 3 0 Thiazole biosynthesis protein ThiG TauD PF02668.16 KXT07305.1 - 1.2e-60 205.6 0.6 1.5e-60 205.2 0.6 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DAO PF01266.24 KXT07306.1 - 2e-28 100.0 0.1 2.9e-28 99.5 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KXT07306.1 - 3.1e-06 26.7 0.0 0.022 14.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KXT07306.1 - 9.6e-06 26.1 0.0 0.18 12.3 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KXT07306.1 - 0.0068 16.4 2.1 0.025 14.6 0.1 3.0 5 0 0 5 5 5 1 FAD-NAD(P)-binding TrkA_N PF02254.18 KXT07306.1 - 0.01 16.1 0.0 0.025 14.9 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_8 PF13450.6 KXT07306.1 - 0.051 13.8 0.7 0.17 12.1 0.2 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain C1_2 PF03107.16 KXT07306.1 - 0.45 10.9 9.1 0.93 9.9 9.1 1.5 1 0 0 1 1 1 0 C1 domain zf-B_box PF00643.24 KXT07306.1 - 0.83 9.9 8.6 1.7 8.9 8.6 1.4 1 0 0 1 1 1 0 B-box zinc finger Rubredoxin_2 PF18073.1 KXT07306.1 - 0.84 9.4 14.0 0.18 11.6 6.4 2.5 2 0 0 2 2 2 0 Rubredoxin metal binding domain ABC_tran PF00005.27 KXT07307.1 - 1.9e-46 158.0 1.2 3.8e-22 79.3 0.1 3.0 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 KXT07307.1 - 7.2e-21 74.0 7.8 7.2e-21 74.0 7.8 3.3 4 0 0 4 4 3 1 ABC transporter AAA_21 PF13304.6 KXT07307.1 - 4.2e-14 53.1 6.6 0.0088 15.9 0.0 4.7 4 1 1 5 5 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KXT07307.1 - 3.8e-09 36.3 0.6 0.075 12.5 0.0 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KXT07307.1 - 1.7e-05 25.4 20.9 0.0078 16.7 0.0 5.1 4 1 1 5 5 5 2 AAA domain AAA_29 PF13555.6 KXT07307.1 - 3.9e-05 23.3 0.9 0.17 11.7 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.6 KXT07307.1 - 3.9e-05 24.2 1.7 0.18 12.4 0.0 3.6 4 0 0 4 4 2 2 AAA domain AAA_16 PF13191.6 KXT07307.1 - 5.5e-05 23.6 1.6 0.093 13.1 0.2 3.4 3 0 0 3 3 3 1 AAA ATPase domain MMR_HSR1 PF01926.23 KXT07307.1 - 5.9e-05 23.1 1.8 0.07 13.2 0.1 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 KXT07307.1 - 0.00012 22.3 0.0 0.7 10.2 0.0 3.0 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KXT07307.1 - 0.00013 21.9 1.8 0.04 13.8 0.0 2.9 3 0 0 3 3 3 1 RsgA GTPase AAA_33 PF13671.6 KXT07307.1 - 0.00025 21.2 0.1 1.1 9.4 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KXT07307.1 - 0.00032 20.5 0.1 0.037 13.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 KXT07307.1 - 0.00033 20.4 2.5 0.4 10.4 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 KXT07307.1 - 0.0014 19.1 0.1 2.1 8.8 0.1 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KXT07307.1 - 0.002 18.1 0.2 0.94 9.4 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_14 PF13173.6 KXT07307.1 - 0.0057 16.7 0.2 6.8 6.7 0.0 3.4 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 KXT07307.1 - 0.0065 16.8 0.0 3.7 8.0 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_15 PF13175.6 KXT07307.1 - 0.015 15.0 15.7 0.37 10.5 0.0 4.4 4 1 0 4 4 4 0 AAA ATPase domain Rad17 PF03215.15 KXT07307.1 - 0.017 15.1 1.2 4.3 7.2 0.0 3.2 2 1 0 3 3 3 0 Rad17 P-loop domain AAA_27 PF13514.6 KXT07307.1 - 0.02 14.5 3.6 3.3 7.2 0.0 3.5 4 0 0 4 4 4 0 AAA domain MeaB PF03308.16 KXT07307.1 - 0.025 13.6 2.7 2.2 7.2 0.1 2.8 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TsaE PF02367.17 KXT07307.1 - 0.033 14.2 0.0 9.1 6.3 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 KXT07307.1 - 0.037 14.3 8.0 0.23 11.7 0.0 3.4 4 0 0 4 4 2 0 AAA domain NTPase_1 PF03266.15 KXT07307.1 - 0.038 13.9 0.1 3.8 7.4 0.0 2.8 2 0 0 2 2 2 0 NTPase BLM10_mid PF16507.5 KXT07307.1 - 0.053 12.2 0.0 0.1 11.3 0.0 1.3 1 0 0 1 1 1 0 Proteasome-substrate-size regulator, mid region cobW PF02492.19 KXT07307.1 - 0.053 13.1 0.8 5.5 6.5 0.4 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 KXT07307.1 - 0.06 13.6 0.1 3.4 7.9 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_5 PF07728.14 KXT07307.1 - 0.077 13.0 0.2 8.4 6.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) MobB PF03205.14 KXT07307.1 - 0.08 12.8 0.3 2.6 8.0 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ATP-synt_ab PF00006.25 KXT07307.1 - 0.13 11.9 0.1 1.1 8.9 0.0 2.1 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Zeta_toxin PF06414.12 KXT07307.1 - 0.2 10.9 2.7 15 4.8 0.0 3.1 3 0 0 3 3 3 0 Zeta toxin DUF3209 PF11483.8 KXT07307.1 - 1.4 9.4 4.7 0.84 10.1 1.5 2.4 2 0 0 2 2 1 0 Protein of unknown function (DUF3209) Dynamin_N PF00350.23 KXT07307.1 - 1.6 8.8 7.0 2.3 8.3 0.0 3.5 4 0 0 4 4 3 0 Dynamin family AAA_17 PF13207.6 KXT07307.1 - 7 7.1 8.4 37 4.7 0.0 3.9 4 0 0 4 4 4 0 AAA domain YkyA PF10368.9 KXT07308.1 - 0.0036 17.0 9.2 0.0036 17.0 9.2 2.7 2 1 1 3 3 3 1 Putative cell-wall binding lipoprotein FlaC_arch PF05377.11 KXT07308.1 - 0.0058 17.0 1.4 4.6 7.7 0.0 3.9 4 0 0 4 4 4 1 Flagella accessory protein C (FlaC) Fez1 PF06818.15 KXT07308.1 - 0.0085 16.6 22.0 0.082 13.3 19.6 3.2 3 1 0 3 3 3 1 Fez1 Vps51 PF08700.11 KXT07308.1 - 0.08 13.0 3.9 1.7 8.8 0.9 3.6 4 0 0 4 4 4 0 Vps51/Vps67 LXG PF04740.12 KXT07308.1 - 0.13 12.0 10.5 1.6 8.4 0.0 3.3 3 1 1 4 4 4 0 LXG domain of WXG superfamily DUF3552 PF12072.8 KXT07308.1 - 0.32 10.4 24.6 0.49 9.8 6.1 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF3552) PKcGMP_CC PF16808.5 KXT07308.1 - 0.33 10.8 18.2 0.47 10.3 0.0 6.0 6 0 0 6 6 6 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF745 PF05335.13 KXT07308.1 - 0.53 10.0 12.3 0.4 10.4 2.9 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF745) Phage_tail_NK PF16532.5 KXT07308.1 - 0.59 9.7 2.5 0.94 9.1 0.1 2.3 3 0 0 3 3 3 0 Sf6-type phage tail needle knob or tip of some Caudovirales Baculo_p24 PF05073.12 KXT07308.1 - 0.74 9.6 4.2 0.98 9.2 0.0 2.5 2 1 0 2 2 2 0 Baculovirus P24 capsid protein MAD PF05557.13 KXT07308.1 - 1.8 6.8 22.7 0.085 11.2 11.1 2.6 2 1 1 3 3 3 0 Mitotic checkpoint protein HMMR_N PF15905.5 KXT07308.1 - 2.4 7.6 18.8 11 5.4 17.5 2.4 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Exonuc_VII_L PF02601.15 KXT07308.1 - 3.9 7.0 17.0 19 4.7 0.0 2.9 2 1 0 2 2 2 0 Exonuclease VII, large subunit TMPIT PF07851.13 KXT07308.1 - 7.3 5.7 9.0 6 6.0 5.5 2.4 2 1 0 2 2 2 0 TMPIT-like protein LAMTOR PF15454.6 KXT07309.1 - 2.6e-08 34.3 2.5 1.5e-07 31.9 0.1 2.3 2 0 0 2 2 2 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator DAHP_synth_2 PF01474.16 KXT07311.1 - 9.8e-203 673.5 0.0 1.1e-202 673.3 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Herpes_UL25 PF01499.16 KXT07311.1 - 0.11 11.0 0.0 0.15 10.5 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family IF4E PF01652.18 KXT07312.1 - 1.4e-54 184.2 0.9 1.7e-54 183.9 0.9 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Sec39 PF08314.11 KXT07313.1 - 1.3e-257 857.1 0.0 3.2e-257 855.8 0.0 1.5 1 1 0 1 1 1 1 Secretory pathway protein Sec39 F-box-like PF12937.7 KXT07313.1 - 0.12 12.3 0.1 0.41 10.6 0.1 2.0 1 0 0 1 1 1 0 F-box-like KH_1 PF00013.29 KXT07314.1 - 1.8e-94 309.5 29.6 1.8e-13 50.1 0.6 13.7 15 1 0 15 15 15 8 KH domain SLS PF14611.6 KXT07314.1 - 9e-15 55.1 3.3 0.088 12.6 0.2 7.2 4 1 2 7 7 7 5 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 KXT07314.1 - 1.1e-12 47.6 22.1 0.064 13.1 0.1 7.7 7 0 0 7 7 7 5 KH domain KH_4 PF13083.6 KXT07314.1 - 2.5e-08 33.7 4.1 1.4 8.8 0.1 5.5 5 0 0 5 5 5 3 KH domain KH_5 PF13184.6 KXT07314.1 - 0.019 15.0 6.5 5.8 7.1 0.0 5.4 6 1 0 6 6 6 0 NusA-like KH domain MOEP19 PF16005.5 KXT07314.1 - 0.066 13.2 0.2 4.2 7.5 0.0 3.5 4 0 0 4 4 4 0 KH-like RNA-binding domain Acylphosphatase PF00708.18 KXT07314.1 - 3.3 8.2 5.2 2.9 8.4 0.1 3.7 4 0 0 4 4 4 0 Acylphosphatase Zn_clus PF00172.18 KXT07315.1 - 6e-06 26.3 10.0 9.7e-06 25.6 10.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MRPL52 PF18699.1 KXT07315.1 - 0.037 14.2 0.5 0.072 13.3 0.5 1.4 1 0 0 1 1 1 0 Mitoribosomal protein mL52 AMP-binding PF00501.28 KXT07316.1 - 2.4e-58 197.7 0.0 3.3e-58 197.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXT07316.1 - 5.4e-09 36.9 0.0 1.2e-08 35.8 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Mito_carr PF00153.27 KXT07319.1 - 2.4e-66 219.7 3.9 2e-23 82.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Chitin_bind_1 PF00187.19 KXT07320.1 - 0.022 15.2 20.5 0.022 15.2 20.5 4.2 3 2 1 4 4 4 0 Chitin recognition protein Septin PF00735.18 KXT07321.1 - 6.5e-10 38.8 0.0 9e-09 35.0 0.0 2.3 1 1 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KXT07321.1 - 5e-05 23.4 0.0 0.0001 22.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KXT07321.1 - 0.0096 16.3 0.0 0.026 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 KXT07321.1 - 0.028 14.4 0.0 0.065 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KXT07321.1 - 0.15 12.3 0.0 0.42 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Rabaptin PF03528.15 KXT07321.1 - 0.26 10.0 1.1 0.6 8.8 0.1 1.9 2 1 0 2 2 2 0 Rabaptin DUF4149 PF13664.6 KXT07323.1 - 5.7e-25 87.6 1.7 1.1e-24 86.7 0.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) Gon7 PF08738.10 KXT07324.1 - 1.6e-11 44.2 3.6 3.6e-11 43.1 3.0 1.7 1 1 1 2 2 2 1 Gon7 family NuDC PF16273.5 KXT07324.1 - 0.021 15.3 8.5 0.021 15.3 8.5 1.4 1 1 0 1 1 1 0 Nuclear distribution C domain TFIIS_C PF01096.18 KXT07325.1 - 3.1e-18 65.3 5.7 3.1e-18 65.3 5.7 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KXT07325.1 - 3.6e-07 29.9 7.0 0.0049 16.7 0.1 3.0 3 0 0 3 3 3 2 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 KXT07325.1 - 0.64 10.0 13.8 0.9 9.6 1.7 2.7 2 1 0 2 2 2 0 Transposase zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 KXT07325.1 - 3.9 7.5 9.3 0.84 9.6 0.3 3.0 3 0 0 3 3 3 0 PhnA Zinc-Ribbon MAGE PF01454.19 KXT07326.1 - 2.4e-58 197.3 0.0 4e-58 196.6 0.0 1.3 1 0 0 1 1 1 1 MAGE family Isochorismatase PF00857.20 KXT07326.1 - 6.6e-14 52.5 0.0 2.2e-13 50.8 0.0 1.9 2 0 0 2 2 2 1 Isochorismatase family Glyco_transf_90 PF05686.12 KXT07328.1 - 2.9e-31 108.8 1.0 4e-31 108.3 1.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 KXT07328.1 - 8.2e-08 32.5 0.3 2.8e-07 30.8 0.1 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 DNA_pol3_gamma3 PF12169.8 KXT07328.1 - 0.083 12.8 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III subunits gamma and tau domain III Sugar_tr PF00083.24 KXT07329.1 - 2.5e-30 105.7 27.2 3.4e-18 65.8 8.5 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KXT07329.1 - 1.7e-16 60.1 38.5 4.3e-12 45.6 26.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PEMT PF04191.13 KXT07329.1 - 0.11 12.8 2.9 0.22 12.0 0.3 2.7 2 0 0 2 2 2 0 Phospholipid methyltransferase DUF21 PF01595.20 KXT07329.1 - 2.1 8.0 8.3 0.61 9.8 0.6 3.3 4 1 1 5 5 5 0 Cyclin M transmembrane N-terminal domain ANAPC4_WD40 PF12894.7 KXT07330.1 - 0.00048 20.4 0.1 0.09 13.1 0.0 3.3 3 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXT07330.1 - 0.00063 20.5 4.8 0.37 11.8 0.0 4.3 4 1 1 5 5 5 2 WD domain, G-beta repeat LisH PF08513.11 KXT07330.1 - 0.017 15.0 0.1 0.03 14.3 0.1 1.4 1 0 0 1 1 1 0 LisH Flexi_CP_N PF08358.10 KXT07330.1 - 0.12 12.4 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Carlavirus coat FMO-like PF00743.19 KXT07331.1 - 3.4e-17 62.1 0.3 7.5e-16 57.6 0.3 2.4 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KXT07331.1 - 5e-11 42.4 0.0 2.2e-07 30.4 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KXT07331.1 - 5.8e-11 42.1 0.2 1.7e-07 30.7 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KXT07331.1 - 4.5e-09 36.0 0.0 0.0006 19.1 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KXT07331.1 - 1.7e-08 34.6 0.0 4.1e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KXT07331.1 - 1.3e-07 31.6 0.0 1e-06 28.6 0.0 2.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KXT07331.1 - 1.7e-05 24.8 0.1 0.07 13.1 0.0 2.7 2 0 0 2 2 2 2 FAD-NAD(P)-binding Amino_oxidase PF01593.24 KXT07331.1 - 0.0028 17.0 0.0 0.87 8.8 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase GIDA PF01134.22 KXT07331.1 - 0.0063 15.6 0.1 0.38 9.8 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 KXT07331.1 - 0.009 16.6 0.1 1.8 9.2 0.1 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KXT07331.1 - 0.017 14.2 0.0 0.033 13.3 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.20 KXT07331.1 - 0.032 14.3 0.0 4.3 7.4 0.0 2.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 KXT07331.1 - 0.097 11.4 0.1 2.9 6.5 0.0 2.5 3 0 0 3 3 3 0 HI0933-like protein Thi4 PF01946.17 KXT07331.1 - 0.15 11.3 0.4 0.77 9.0 0.0 2.1 2 0 0 2 2 2 0 Thi4 family FAM184 PF15665.5 KXT07332.1 - 0.0029 17.4 14.9 0.0029 17.4 14.9 8.6 2 1 4 7 7 7 3 Family with sequence similarity 184, A and B Cyclin_N PF00134.23 KXT07334.1 - 2e-45 153.6 0.0 1.1e-44 151.2 0.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KXT07334.1 - 3.5e-34 117.4 0.0 6.1e-34 116.7 0.0 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain Sugar_tr PF00083.24 KXT07336.1 - 8.2e-81 272.2 23.6 9.5e-81 271.9 23.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXT07336.1 - 3.3e-18 65.7 23.7 3.3e-18 65.7 23.7 2.1 1 1 0 2 2 2 1 Major Facilitator Superfamily Steroid_dh PF02544.16 KXT07338.1 - 1.3e-31 109.6 0.1 2e-31 109.0 0.1 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KXT07338.1 - 0.00011 21.8 0.3 0.00015 21.3 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 KXT07338.1 - 0.047 14.1 0.4 0.13 12.7 0.0 1.9 2 1 1 3 3 3 0 Phospholipid methyltransferase AAA PF00004.29 KXT07339.1 - 5.2e-39 133.7 0.0 8e-38 129.8 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXT07339.1 - 7.5e-11 41.7 0.4 7.2e-09 35.3 0.1 2.6 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 KXT07339.1 - 8.4e-05 23.0 0.1 0.0017 18.8 0.1 2.8 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KXT07339.1 - 0.0002 21.2 0.0 0.0004 20.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KXT07339.1 - 0.00073 19.8 0.3 0.033 14.5 0.1 3.2 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KXT07339.1 - 0.001 19.2 0.0 0.012 15.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 KXT07339.1 - 0.0011 18.2 0.0 0.0021 17.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 KXT07339.1 - 0.0039 17.2 0.0 0.012 15.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KXT07339.1 - 0.019 14.3 0.1 0.048 13.1 0.1 1.6 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KXT07339.1 - 0.022 14.8 0.0 0.058 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KXT07339.1 - 0.024 14.9 0.0 0.054 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KXT07339.1 - 0.035 14.6 0.0 0.089 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KXT07339.1 - 0.035 13.8 0.0 0.094 12.4 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein TniB PF05621.11 KXT07339.1 - 0.043 13.2 0.0 1.9 7.8 0.0 2.5 1 1 1 2 2 2 0 Bacterial TniB protein RNA_helicase PF00910.22 KXT07339.1 - 0.043 14.2 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase IPT PF01745.16 KXT07339.1 - 0.052 12.9 0.0 0.093 12.1 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase SUR7 PF06687.12 KXT07339.1 - 0.1 12.2 2.9 0.19 11.3 2.9 1.4 1 0 0 1 1 1 0 SUR7/PalI family AAA_17 PF13207.6 KXT07339.1 - 0.11 13.0 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KXT07339.1 - 0.17 11.6 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Hydin_ADK PF17213.3 KXT07339.1 - 6.9 6.9 6.8 10 6.3 0.1 3.1 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain Acyltransferase PF01553.21 KXT07340.1 - 5.4e-14 52.0 0.0 8.5e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 KXT07340.1 - 1.8e-07 31.2 0.1 4.3e-07 29.9 0.1 1.6 1 0 0 1 1 1 1 Acyltransferase C-terminus MASE2 PF05230.11 KXT07340.1 - 1.5 8.9 5.6 0.81 9.8 2.0 2.2 2 0 0 2 2 2 0 MASE2 domain SGL PF08450.12 KXT07342.1 - 0.0089 15.6 0.6 0.6 9.6 0.2 2.5 2 1 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region MMR_HSR1 PF01926.23 KXT07343.1 - 4.4e-05 23.5 0.0 0.55 10.3 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase ATPase-cat_bd PF12156.8 KXT07343.1 - 0.17 12.6 0.0 0.51 11.1 0.0 1.8 1 1 0 1 1 1 0 Putative metal-binding domain of cation transport ATPase Reprolysin_5 PF13688.6 KXT07344.1 - 1.3e-55 188.6 10.1 1.3e-55 188.6 10.1 2.6 2 1 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 KXT07344.1 - 3.3e-48 164.2 5.4 8.8e-48 162.8 5.4 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KXT07344.1 - 1.4e-41 142.3 5.3 3.1e-41 141.3 5.3 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 KXT07344.1 - 3.2e-17 63.1 34.6 3.2e-17 63.1 34.6 4.5 3 1 0 3 3 3 1 Disintegrin Reprolysin_3 PF13582.6 KXT07344.1 - 3.9e-08 33.8 1.9 1.8e-07 31.7 0.2 2.6 1 1 1 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like ADAM_CR_2 PF17771.1 KXT07344.1 - 0.00022 21.7 12.9 0.00022 21.7 12.9 5.1 1 1 3 4 4 4 1 ADAM cysteine-rich domain Pep_M12B_propep PF01562.19 KXT07344.1 - 0.025 14.8 0.6 0.11 12.8 0.1 2.3 3 0 0 3 3 3 0 Reprolysin family propeptide DUF588 PF04535.12 KXT07345.1 - 0.0057 16.5 0.8 0.0057 16.5 0.8 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF588) TAFII55_N PF04658.13 KXT07346.1 - 4.2e-49 166.4 0.1 1.1e-48 165.0 0.1 1.7 1 0 0 1 1 1 1 TAFII55 protein conserved region I_LWEQ PF01608.17 KXT07346.1 - 0.14 12.4 6.1 0.36 11.1 6.1 1.7 1 0 0 1 1 1 0 I/LWEQ domain Thioredoxin_4 PF13462.6 KXT07346.1 - 0.2 11.8 4.1 0.54 10.4 4.1 1.7 1 0 0 1 1 1 0 Thioredoxin ADH_zinc_N PF00107.26 KXT07347.1 - 0.076 13.0 0.0 0.09 12.8 0.0 1.1 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Asp PF00026.23 KXT07348.1 - 2.5e-46 158.6 0.1 3.7e-46 158.0 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KXT07348.1 - 9.2e-07 29.3 0.3 0.00073 19.8 0.2 3.1 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KXT07348.1 - 0.00012 22.6 0.5 0.3 11.7 0.0 3.7 3 0 0 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.6 KXT07348.1 - 0.015 15.8 0.4 1.4 9.5 0.0 3.1 4 0 0 4 4 4 0 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 KXT07348.1 - 0.028 14.2 0.0 0.18 11.6 0.0 2.2 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Phage_sheath_1N PF17481.2 KXT07348.1 - 0.064 13.7 0.1 0.24 11.9 0.0 1.8 1 1 1 2 2 2 0 Phage tail sheath protein beta-sandwich domain Glyco_hydro_32N PF00251.20 KXT07349.1 - 3.9e-34 118.6 0.0 5.5e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_43 PF04616.14 KXT07349.1 - 9.9e-09 34.9 0.0 4.2e-05 23.0 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 Glyco_hydro_68 PF02435.16 KXT07349.1 - 0.0052 15.7 0.0 0.011 14.6 0.0 1.5 1 0 0 1 1 1 1 Levansucrase/Invertase EPTP PF03736.17 KXT07349.1 - 0.058 13.4 0.0 0.18 11.8 0.0 1.8 1 0 0 1 1 1 0 EPTP domain DUF3822 PF12864.7 KXT07349.1 - 0.23 10.6 0.0 0.41 9.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3822) Tim17 PF02466.19 KXT07350.1 - 6e-12 45.9 0.8 1.2e-11 45.0 0.8 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family PAN_4 PF14295.6 KXT07351.1 - 0.15 12.0 2.0 0.42 10.5 2.0 1.8 1 0 0 1 1 1 0 PAN domain RasGEF PF00617.19 KXT07352.1 - 5.2e-46 157.1 0.2 1.1e-45 156.0 0.2 1.6 1 0 0 1 1 1 1 RasGEF domain DUF2236 PF09995.9 KXT07352.1 - 6.3e-33 114.9 0.0 1.6e-32 113.5 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) RasGEF_N PF00618.20 KXT07352.1 - 3e-13 49.9 0.1 1.2e-12 48.0 0.0 2.0 2 0 0 2 2 2 1 RasGEF N-terminal motif Ras PF00071.22 KXT07352.1 - 9.4e-06 25.3 0.0 0.0004 20.0 0.0 2.3 2 0 0 2 2 2 1 Ras family RsgA_GTPase PF03193.16 KXT07352.1 - 0.03 14.2 0.0 7.9 6.4 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 KXT07352.1 - 0.098 13.0 0.0 0.46 10.9 0.0 2.3 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 KXT07352.1 - 0.14 12.2 0.1 0.48 10.5 0.1 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 KXT07352.1 - 0.16 11.7 0.0 11 5.7 0.0 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 KXT07352.1 - 0.18 11.3 0.0 3.3 7.2 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Hva1_TUDOR PF11160.8 KXT07353.1 - 2.2e-18 66.2 0.4 2.2e-18 66.2 0.4 3.3 3 1 0 3 3 3 1 Hypervirulence associated proteins TUDOR domain adh_short_C2 PF13561.6 KXT07354.1 - 8.9e-62 208.7 1.4 1.1e-61 208.3 1.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KXT07354.1 - 6.4e-53 179.1 1.8 8.8e-53 178.7 1.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KXT07354.1 - 3.6e-13 49.8 0.5 5.3e-13 49.3 0.5 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KXT07354.1 - 5.2e-05 22.8 0.2 8.4e-05 22.1 0.2 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PfkB PF00294.24 KXT07354.1 - 0.002 17.5 1.1 0.0038 16.6 0.8 1.5 1 1 0 1 1 1 1 pfkB family carbohydrate kinase ThiF PF00899.21 KXT07354.1 - 0.061 12.7 0.1 0.13 11.6 0.1 1.4 1 0 0 1 1 1 0 ThiF family SMN PF06003.12 KXT07355.1 - 0.28 10.4 2.4 0.45 9.7 2.4 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) DIOX_N PF14226.6 KXT07356.1 - 1.9e-21 77.0 0.0 3.2e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KXT07356.1 - 8.5e-21 74.3 0.0 1.6e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily KCH PF16944.5 KXT07357.1 - 1.4e-97 326.4 11.2 1.7e-97 326.1 11.2 1.1 1 0 0 1 1 1 1 Fungal potassium channel DUF1682 PF07946.14 KXT07357.1 - 0.2 10.8 0.0 0.3 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Lig_chan PF00060.26 KXT07357.1 - 4.3 7.2 9.0 29 4.5 9.0 2.1 1 1 0 1 1 1 0 Ligand-gated ion channel Glyco_transf_8 PF01501.20 KXT07358.1 - 1e-17 64.6 2.7 2.4e-17 63.4 0.3 2.5 2 1 0 2 2 2 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 KXT07358.1 - 0.13 11.6 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 Mannosyltransferase putative Snapin_Pallidin PF14712.6 KXT07359.1 - 0.00075 19.9 1.9 0.47 10.9 0.6 2.6 2 0 0 2 2 2 2 Snapin/Pallidin DUF1664 PF07889.12 KXT07359.1 - 0.0062 16.6 9.2 1.3 9.0 0.1 3.4 1 1 2 3 3 3 2 Protein of unknown function (DUF1664) YscO PF07321.12 KXT07359.1 - 0.0074 16.3 7.1 0.0082 16.1 4.5 2.1 2 0 0 2 2 2 1 Type III secretion protein YscO Laminin_II PF06009.12 KXT07359.1 - 0.0096 15.9 1.8 3.5 7.6 0.2 2.7 2 1 0 2 2 2 2 Laminin Domain II AIP3 PF03915.13 KXT07359.1 - 0.014 14.5 3.1 0.026 13.6 1.8 1.9 2 0 0 2 2 2 0 Actin interacting protein 3 DUF16 PF01519.16 KXT07359.1 - 0.015 15.8 1.6 6.3 7.3 0.5 2.7 2 1 0 2 2 2 0 Protein of unknown function DUF16 AATF-Che1 PF13339.6 KXT07359.1 - 0.022 15.5 0.5 0.71 10.6 0.4 2.5 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor Cluap1 PF10234.9 KXT07359.1 - 0.03 13.7 4.9 0.67 9.3 0.0 2.3 1 1 1 2 2 2 0 Clusterin-associated protein-1 DASH_Spc34 PF08657.10 KXT07359.1 - 0.044 13.6 0.8 0.087 12.6 0.8 1.5 1 0 0 1 1 1 0 DASH complex subunit Spc34 BLOC1_2 PF10046.9 KXT07359.1 - 0.058 13.7 3.1 2.3 8.6 0.0 3.0 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Apolipoprotein PF01442.18 KXT07359.1 - 0.1 12.5 12.4 0.37 10.6 12.4 2.1 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain COG2 PF06148.11 KXT07359.1 - 0.14 12.2 6.4 0.17 12.0 0.5 3.2 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF948 PF06103.11 KXT07359.1 - 0.18 12.1 3.9 28 5.0 0.0 3.7 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) PBECR1 PF18809.1 KXT07359.1 - 0.21 12.3 2.6 0.59 10.8 0.5 2.5 2 1 1 3 3 2 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease1 Mer2 PF09074.10 KXT07359.1 - 0.24 11.2 5.8 0.098 12.5 2.6 1.8 1 1 1 2 2 2 0 Mer2 DUF2433 PF10360.9 KXT07359.1 - 0.38 10.9 1.9 0.72 10.0 0.8 2.0 2 1 0 2 2 1 0 Protein of unknown function (DUF2433) DUF4335 PF14233.6 KXT07359.1 - 0.38 10.6 1.8 0.52 10.2 0.9 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF4335) H-kinase_dim PF02895.14 KXT07359.1 - 0.41 11.1 2.4 34 4.9 0.1 3.1 3 0 0 3 3 3 0 Signal transducing histidine kinase, homodimeric domain CENP-H PF05837.12 KXT07359.1 - 1.2 9.5 6.5 0.84 10.1 3.7 2.0 2 0 0 2 2 2 0 Centromere protein H (CENP-H) KxDL PF10241.9 KXT07359.1 - 1.5 9.1 5.9 12 6.2 0.2 3.8 2 1 1 3 3 3 0 Uncharacterized conserved protein DUF745 PF05335.13 KXT07359.1 - 1.7 8.3 8.8 1.6 8.5 3.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF745) PRKG1_interact PF15898.5 KXT07359.1 - 4.4 8.3 6.8 9.3 7.2 4.2 2.3 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain p450 PF00067.22 KXT07362.1 - 6.7e-94 315.2 0.0 7.8e-94 315.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_L13 PF00572.18 KXT07363.1 - 9.8e-10 38.8 0.0 7.6e-08 32.6 0.0 2.3 1 1 0 1 1 1 1 Ribosomal protein L13 Pkinase PF00069.25 KXT07364.1 - 2.3e-43 148.5 0.0 3.6e-43 147.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT07364.1 - 4.8e-30 104.7 0.0 7.2e-30 104.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXT07364.1 - 0.02 14.9 0.0 6.5 6.6 0.0 2.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXT07364.1 - 0.072 11.9 0.1 0.19 10.5 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Kinase-like PF14531.6 KXT07364.1 - 0.1 11.9 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Med31 PF05669.12 KXT07365.1 - 8.9e-35 118.6 1.3 1.1e-34 118.3 1.3 1.1 1 0 0 1 1 1 1 SOH1 EthD PF07110.11 KXT07366.1 - 0.0039 18.3 0.2 0.022 15.9 0.2 1.9 1 1 0 1 1 1 1 EthD domain Peptidase_M28 PF04389.17 KXT07367.1 - 2e-37 128.8 0.0 3.5e-37 128.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KXT07367.1 - 7.6e-05 22.5 0.0 0.00018 21.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Fungal_trans PF04082.18 KXT07368.1 - 2.2e-26 92.5 0.0 3.7e-26 91.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT07368.1 - 2.7e-11 43.4 12.6 4.4e-11 42.7 12.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AmiS_UreI PF02293.15 KXT07368.1 - 0.1 12.6 0.3 0.23 11.4 0.3 1.5 1 0 0 1 1 1 0 AmiS/UreI family transporter NUC153 PF08159.12 KXT07369.1 - 8.7e-11 41.4 4.8 1.9e-10 40.4 4.8 1.6 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 KXT07369.1 - 0.16 12.9 1.3 73 4.5 0.0 3.9 4 0 0 4 4 4 0 WD domain, G-beta repeat Adeno_E3_CR2 PF02439.15 KXT07370.1 - 0.033 13.9 0.3 0.055 13.2 0.3 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Arrestin_C PF02752.22 KXT07371.1 - 6.1e-09 36.4 0.0 3.2e-08 34.1 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KXT07371.1 - 0.011 15.8 0.2 0.5 10.4 0.0 3.3 3 1 0 3 3 3 0 Arrestin (or S-antigen), N-terminal domain SF3b10 PF07189.11 KXT07372.1 - 3.2e-36 123.3 0.0 3.5e-36 123.1 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) GTPase_binding PF09027.10 KXT07372.1 - 0.15 12.1 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 GTPase binding LMBR1 PF04791.16 KXT07373.1 - 0.64 8.9 1.7 0.73 8.7 1.7 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4407 PF14362.6 KXT07373.1 - 1.3 8.4 3.8 1.5 8.1 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BING4CT PF08149.11 KXT07374.1 - 1.6e-38 130.4 0.0 3.2e-35 119.8 0.0 3.2 3 0 0 3 3 3 2 BING4CT (NUC141) domain ANAPC4_WD40 PF12894.7 KXT07374.1 - 6.9e-09 35.9 0.2 2.8 8.3 0.0 5.9 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KXT07374.1 - 0.00012 22.8 0.0 0.46 11.4 0.0 4.5 4 1 1 5 5 5 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 KXT07374.1 - 0.00012 21.3 0.2 0.008 15.3 0.0 2.2 2 0 0 2 2 2 2 Coatomer WD associated region An_peroxidase PF03098.15 KXT07375.1 - 1.8e-32 112.7 0.0 1.2e-10 40.6 0.0 4.2 2 1 1 3 3 3 3 Animal haem peroxidase p450 PF00067.22 KXT07375.1 - 1.9e-08 33.5 0.0 5.4e-06 25.4 0.0 2.3 2 0 0 2 2 2 2 Cytochrome P450 BLI1 PF17324.2 KXT07375.1 - 0.12 13.0 0.1 19 5.9 0.0 2.7 2 0 0 2 2 2 0 BLOC-1 interactor 1 An_peroxidase PF03098.15 KXT07376.1 - 1.8e-32 112.7 0.0 1.2e-10 40.6 0.0 4.2 2 1 1 3 3 3 3 Animal haem peroxidase p450 PF00067.22 KXT07376.1 - 1.9e-08 33.5 0.0 5.4e-06 25.4 0.0 2.3 2 0 0 2 2 2 2 Cytochrome P450 BLI1 PF17324.2 KXT07376.1 - 0.12 13.0 0.1 19 5.9 0.0 2.7 2 0 0 2 2 2 0 BLOC-1 interactor 1 NAGLU PF05089.12 KXT07377.1 - 2.6e-130 434.2 11.5 7.8e-96 320.9 0.5 2.8 3 0 0 3 3 3 2 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.7 KXT07377.1 - 2.3e-71 240.5 4.8 3.4e-71 239.9 4.8 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.7 KXT07377.1 - 2e-19 69.2 0.0 4.7e-19 68.0 0.0 1.7 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain Glyco_transf_90 PF05686.12 KXT07378.1 - 2.1e-21 76.3 2.6 2.7e-21 75.9 2.6 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 MFS_1 PF07690.16 KXT07379.1 - 3.3e-18 65.7 28.4 3.3e-18 65.7 28.4 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily TRIQK PF15168.6 KXT07379.1 - 0.021 14.7 0.2 0.14 12.1 0.1 2.2 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family Sugar_tr PF00083.24 KXT07379.1 - 0.023 13.5 20.1 0.74 8.6 19.3 2.7 1 1 0 1 1 1 0 Sugar (and other) transporter SNF2_N PF00176.23 KXT07380.1 - 1e-36 126.4 0.0 4.5e-36 124.3 0.0 1.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXT07380.1 - 9.3e-06 26.0 0.0 1.8e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXT07380.1 - 0.01 15.8 0.0 4.9 7.1 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit CUTL PF16557.5 KXT07380.1 - 0.15 12.3 0.1 0.47 10.7 0.1 1.8 1 0 0 1 1 1 0 CUT1-like DNA-binding domain of SATB zf-H2C2_2 PF13465.6 KXT07381.1 - 1.5e-09 37.9 9.4 2.8e-08 33.8 1.3 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 KXT07381.1 - 2.4e-06 27.4 0.9 0.015 15.2 0.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KXT07381.1 - 5.4e-06 26.6 0.3 5.4e-06 26.6 0.3 4.0 4 1 0 4 4 4 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXT07381.1 - 0.00027 21.5 5.7 0.006 17.3 0.2 3.0 3 0 0 3 3 3 1 C2H2-type zinc finger FOXP-CC PF16159.5 KXT07381.1 - 0.024 15.2 0.1 0.024 15.2 0.1 4.3 4 1 1 5 5 5 0 FOXP coiled-coil domain Zap1_zf2 PF18217.1 KXT07381.1 - 0.094 12.7 0.5 0.094 12.7 0.5 2.6 2 0 0 2 2 2 0 Zap1 zinc finger 2 zf-H2C2_5 PF13909.6 KXT07381.1 - 0.12 12.1 0.4 3.4 7.5 0.0 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KXT07381.1 - 0.14 12.5 0.3 4.2 7.8 0.0 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Cys_Met_Meta_PP PF01053.20 KXT07382.1 - 9.1e-140 465.5 0.0 1e-139 465.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KXT07382.1 - 8.9e-08 31.7 0.1 1.6e-07 30.8 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KXT07382.1 - 1.8e-05 24.2 0.2 3.8e-05 23.2 0.2 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KXT07382.1 - 4.8e-05 22.5 0.1 9.6e-05 21.5 0.1 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KXT07382.1 - 0.001 18.4 0.0 0.0024 17.2 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase Big_3_5 PF16640.5 KXT07382.1 - 0.25 11.5 2.2 1 9.6 1.1 2.2 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) NAD_binding_3 PF03447.16 KXT07382.1 - 0.63 10.7 3.3 79 3.9 0.1 3.3 3 0 0 3 3 3 0 Homoserine dehydrogenase, NAD binding domain Ribosomal_L2_C PF03947.18 KXT07383.1 - 6.1e-49 165.4 4.6 1.8e-48 163.9 4.1 2.0 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KXT07383.1 - 3.2e-23 81.5 0.4 7.8e-23 80.2 0.4 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Diphthamide_syn PF01866.17 KXT07384.1 - 3e-87 292.9 0.0 3.7e-87 292.6 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein TPP_enzyme_N PF02776.18 KXT07385.1 - 5.7e-46 156.3 0.5 5.6e-45 153.0 0.0 2.5 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KXT07385.1 - 1.6e-23 83.2 0.8 3.5e-23 82.1 0.2 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KXT07385.1 - 1.3e-21 76.8 0.0 2.2e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Zn_clus PF00172.18 KXT07386.1 - 3.3e-08 33.5 9.9 5.1e-08 32.9 9.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KXT07387.1 - 2.5e-21 75.9 0.0 4.8e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT07387.1 - 4.5e-09 36.3 8.6 8.7e-09 35.4 8.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L6 PF00347.23 KXT07388.1 - 1.4e-22 80.1 0.0 1.3e-10 41.8 0.0 3.1 3 1 0 3 3 3 2 Ribosomal protein L6 zf-CSL PF05207.13 KXT07389.1 - 1.3e-22 79.2 0.8 1.6e-22 79.0 0.8 1.1 1 0 0 1 1 1 1 CSL zinc finger AAA PF00004.29 KXT07390.1 - 8.7e-47 158.9 0.0 4.1e-43 147.0 0.0 3.1 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KXT07390.1 - 8.7e-06 25.5 2.5 0.0036 17.1 0.0 2.8 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 KXT07390.1 - 0.00011 22.7 0.1 0.024 15.0 0.0 3.1 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KXT07390.1 - 0.00016 21.5 0.0 0.00056 19.7 0.0 1.9 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Parvo_NS1 PF01057.17 KXT07390.1 - 0.00054 19.2 0.0 0.0011 18.2 0.0 1.4 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_2 PF07724.14 KXT07390.1 - 0.0026 17.9 0.0 0.009 16.1 0.0 1.9 2 1 0 2 2 1 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 KXT07390.1 - 0.005 17.2 0.0 0.015 15.6 0.0 1.9 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.13 KXT07390.1 - 0.0055 16.0 0.0 0.014 14.6 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 KXT07390.1 - 0.0075 16.0 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 KXT07390.1 - 0.0092 16.3 0.0 0.057 13.7 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_25 PF13481.6 KXT07390.1 - 0.017 14.7 0.0 0.077 12.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 KXT07390.1 - 0.025 13.9 0.0 0.053 12.9 0.0 1.4 1 0 0 1 1 1 0 KaiC Mg_chelatase PF01078.21 KXT07390.1 - 0.027 13.8 0.1 0.057 12.8 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KXT07390.1 - 0.036 13.6 0.0 0.07 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 KXT07390.1 - 0.037 14.0 0.0 0.13 12.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KXT07390.1 - 0.051 14.1 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KXT07390.1 - 0.059 12.8 0.0 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein TsaE PF02367.17 KXT07390.1 - 0.066 13.2 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 KXT07390.1 - 0.15 12.3 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KXT07390.1 - 0.15 12.2 0.0 0.44 10.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain Putative_PNPOx PF01243.20 KXT07391.1 - 4.6e-08 33.1 0.0 4.8e-06 26.7 0.0 2.6 2 1 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase FAD_binding_6 PF00970.24 KXT07391.1 - 0.062 13.7 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain MSL1_dimer PF16801.5 KXT07392.1 - 0.29 10.9 0.5 0.29 10.9 0.5 2.6 3 0 0 3 3 3 0 Dimerisation domain of Male-specific-Lethal 1 DUF4407 PF14362.6 KXT07392.1 - 3.1 7.1 7.5 3.7 6.8 7.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Presenilin PF01080.17 KXT07392.1 - 4 6.1 8.0 4.2 6.0 8.0 1.1 1 0 0 1 1 1 0 Presenilin Cu-oxidase_3 PF07732.15 KXT07393.1 - 8.8e-40 135.4 5.1 4.4e-39 133.2 2.3 3.0 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KXT07393.1 - 4.4e-37 126.9 8.6 1.6e-32 112.1 0.2 3.7 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.22 KXT07393.1 - 3.6e-34 118.2 0.5 9.8e-34 116.8 0.5 1.7 1 0 0 1 1 1 1 Multicopper oxidase PTCB-BRCT PF12738.7 KXT07394.1 - 0.0019 18.1 0.0 0.0041 17.0 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 KXT07394.1 - 0.022 15.1 0.0 0.058 13.8 0.0 1.7 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KXT07394.1 - 0.17 12.3 0.0 0.47 10.9 0.0 1.7 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain Glyco_hydro_16 PF00722.21 KXT07395.1 - 1.2e-05 24.9 0.0 3.2e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Hamartin PF04388.12 KXT07395.1 - 6.6 5.3 8.4 8.4 4.9 8.4 1.1 1 0 0 1 1 1 0 Hamartin protein p450 PF00067.22 KXT07396.1 - 2.8e-71 240.7 0.0 1.4e-70 238.4 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 DUF2470 PF10615.9 KXT07397.1 - 2.1e-20 73.1 0.1 1.9e-19 70.0 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2470) Pkinase PF00069.25 KXT07398.1 - 1.2e-30 106.8 0.0 5.2e-29 101.4 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT07398.1 - 3.1e-09 36.5 0.0 0.00014 21.2 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase DUF4965 PF16335.5 KXT07399.1 - 1.4e-69 233.2 0.3 2.3e-69 232.5 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF5127 PF17168.4 KXT07399.1 - 6.6e-60 202.7 0.7 1.1e-59 202.0 0.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF1793 PF08760.11 KXT07399.1 - 3e-58 196.9 0.1 7.8e-58 195.6 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KXT07399.1 - 9.7e-11 41.1 0.1 4e-10 39.1 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4964) Glyco_hydr_116N PF12215.8 KXT07399.1 - 0.04 13.4 0.1 0.078 12.4 0.1 1.4 1 0 0 1 1 1 0 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term Ribosomal_S5_C PF03719.15 KXT07399.1 - 0.092 12.2 0.0 0.22 11.0 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S5, C-terminal domain PDZ_1 PF12812.7 KXT07399.1 - 0.16 12.0 0.0 0.51 10.4 0.0 1.8 1 0 0 1 1 1 0 PDZ-like domain DUF3546 PF12066.8 KXT07400.1 - 1.5e-31 108.8 1.4 4.9e-31 107.2 1.4 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 KXT07400.1 - 4e-16 60.0 0.4 9e-16 58.8 0.2 1.7 1 1 0 1 1 1 1 Arsenite-resistance protein 2 DUF4187 PF13821.6 KXT07400.1 - 2.4e-13 49.6 0.2 6.6e-13 48.2 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) zf-C2H2_aberr PF17017.5 KXT07400.1 - 0.23 11.6 0.2 0.41 10.8 0.2 1.3 1 0 0 1 1 1 0 Aberrant zinc-finger DUF3546 PF12066.8 KXT07401.1 - 1.5e-31 108.8 1.4 4.9e-31 107.2 1.4 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 KXT07401.1 - 4e-16 60.0 0.4 9e-16 58.8 0.2 1.7 1 1 0 1 1 1 1 Arsenite-resistance protein 2 DUF4187 PF13821.6 KXT07401.1 - 2.4e-13 49.6 0.2 6.6e-13 48.2 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) zf-C2H2_aberr PF17017.5 KXT07401.1 - 0.23 11.6 0.2 0.41 10.8 0.2 1.3 1 0 0 1 1 1 0 Aberrant zinc-finger Aldo_ket_red PF00248.21 KXT07402.1 - 2.7e-49 168.0 0.0 3e-49 167.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family F-box PF00646.33 KXT07403.1 - 6.6e-07 29.1 0.3 2.4e-06 27.2 0.1 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KXT07403.1 - 0.00066 19.5 0.0 0.002 18.0 0.0 1.9 1 0 0 1 1 1 1 F-box-like Cupin_5 PF06172.11 KXT07404.1 - 1.6e-50 170.9 0.0 2.1e-50 170.5 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) SET PF00856.28 KXT07405.1 - 2.7e-10 40.9 0.0 1.7e-09 38.3 0.0 2.2 2 1 0 2 2 2 1 SET domain Casc1_N PF15927.5 KXT07406.1 - 0.031 14.0 0.1 0.034 13.9 0.1 1.2 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus DnaJ-X PF14308.6 KXT07406.1 - 0.039 13.4 0.1 0.043 13.3 0.1 1.0 1 0 0 1 1 1 0 X-domain of DnaJ-containing Sugar_tr PF00083.24 KXT07407.1 - 9.5e-100 334.6 21.0 1.1e-99 334.4 21.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXT07407.1 - 3.8e-25 88.6 26.1 3.8e-25 88.6 26.1 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KXT07407.1 - 2.8e-05 22.8 3.2 2.8e-05 22.8 3.2 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) BT1 PF03092.16 KXT07407.1 - 0.00064 18.1 0.1 0.0018 16.6 0.1 1.7 1 0 0 1 1 1 1 BT1 family Methyltransf_11 PF08241.12 KXT07408.1 - 8e-12 45.7 0.0 4.2e-11 43.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXT07408.1 - 4.6e-11 43.3 0.0 6.4e-10 39.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXT07408.1 - 9e-07 29.6 0.0 2.1e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXT07408.1 - 1.4e-05 24.9 0.0 2.3e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KXT07408.1 - 7.2e-05 22.2 0.0 0.00014 21.3 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KXT07408.1 - 8e-05 22.5 0.0 0.00017 21.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Nucleotid_trans PF03407.16 KXT07408.1 - 0.063 13.2 0.1 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Nucleotide-diphospho-sugar transferase TspO_MBR PF03073.15 KXT07409.1 - 8e-45 152.2 5.2 1.1e-44 151.7 5.2 1.1 1 0 0 1 1 1 1 TspO/MBR family DUF5353 PF17304.2 KXT07409.1 - 1 9.2 4.7 2.5 7.9 0.0 2.9 2 1 0 2 2 2 0 Family of unknown function (DUF5353) TspO_MBR PF03073.15 KXT07410.1 - 8e-45 152.2 5.2 1.1e-44 151.7 5.2 1.1 1 0 0 1 1 1 1 TspO/MBR family DUF5353 PF17304.2 KXT07410.1 - 1 9.2 4.7 2.5 7.9 0.0 2.9 2 1 0 2 2 2 0 Family of unknown function (DUF5353) TspO_MBR PF03073.15 KXT07411.1 - 8e-45 152.2 5.2 1.1e-44 151.7 5.2 1.1 1 0 0 1 1 1 1 TspO/MBR family DUF5353 PF17304.2 KXT07411.1 - 1 9.2 4.7 2.5 7.9 0.0 2.9 2 1 0 2 2 2 0 Family of unknown function (DUF5353) TspO_MBR PF03073.15 KXT07412.1 - 8e-45 152.2 5.2 1.1e-44 151.7 5.2 1.1 1 0 0 1 1 1 1 TspO/MBR family DUF5353 PF17304.2 KXT07412.1 - 1 9.2 4.7 2.5 7.9 0.0 2.9 2 1 0 2 2 2 0 Family of unknown function (DUF5353) zf-C2H2_jaz PF12171.8 KXT07413.1 - 0.09 13.1 0.4 0.09 13.1 0.4 5.6 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding Ogr_Delta PF04606.12 KXT07413.1 - 0.5 10.4 4.6 0.53 10.3 1.8 2.5 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger zf-C2H2 PF00096.26 KXT07414.1 - 0.0004 20.7 30.8 0.086 13.3 5.2 6.6 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXT07414.1 - 0.011 16.5 35.4 0.036 14.9 4.4 7.4 7 0 0 7 7 7 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KXT07414.1 - 0.087 13.1 0.4 0.087 13.1 0.4 5.7 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding Ogr_Delta PF04606.12 KXT07414.1 - 9.2 6.3 8.7 0.51 10.3 1.8 2.4 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger zf-C2H2_jaz PF12171.8 KXT07415.1 - 0.09 13.1 0.4 0.09 13.1 0.4 5.6 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding Ogr_Delta PF04606.12 KXT07415.1 - 0.5 10.4 4.6 0.53 10.3 1.8 2.5 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger Pal1 PF08316.11 KXT07418.1 - 2e-44 151.7 5.6 2.6e-44 151.3 0.5 3.0 2 1 0 2 2 2 1 Pal1 cell morphology protein ABM PF03992.16 KXT07419.1 - 0.0018 18.3 0.0 0.012 15.7 0.0 2.2 2 0 0 2 2 2 1 Antibiotic biosynthesis monooxygenase ABM PF03992.16 KXT07420.1 - 0.0018 18.3 0.0 0.012 15.7 0.0 2.2 2 0 0 2 2 2 1 Antibiotic biosynthesis monooxygenase Sugar_tr PF00083.24 KXT07421.1 - 2.5e-85 287.0 22.1 2.9e-85 286.8 22.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KXT07421.1 - 3.6e-13 49.2 32.7 7.5e-11 41.5 24.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KXT07421.1 - 0.00018 20.9 1.7 0.00018 20.9 1.7 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 KXT07421.1 - 0.28 10.0 9.3 0.098 11.5 4.4 2.4 2 0 0 2 2 2 0 MFS_1 like family Med13_C PF06333.12 KXT07422.1 - 1.4e-83 280.9 4.7 2.5e-82 276.8 0.0 2.4 2 0 0 2 2 2 2 Mediator complex subunit 13 C-terminal domain Med13_N PF11597.8 KXT07422.1 - 3.6e-42 144.8 0.8 3.6e-42 144.8 0.8 1.8 2 0 0 2 2 2 1 Mediator complex subunit 13 N-terminal MID_MedPIWI PF18296.1 KXT07422.1 - 1.8e-35 122.9 3.9 6.8e-34 117.8 0.2 2.7 2 1 0 2 2 2 1 MID domain of medPIWI DHHC PF01529.20 KXT07423.1 - 1.8e-33 115.5 0.5 1.8e-33 115.5 0.5 2.3 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ku PF02735.16 KXT07424.1 - 1.7e-37 129.1 0.0 4.3e-37 127.8 0.0 1.6 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 KXT07424.1 - 5e-33 113.8 0.3 1.8e-32 112.0 0.1 2.1 2 0 0 2 2 2 1 Ku C terminal domain like Ku_N PF03731.15 KXT07424.1 - 1.9e-15 57.2 0.3 3.6e-15 56.3 0.3 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA PF00092.28 KXT07424.1 - 0.0005 20.4 0.1 0.0015 18.8 0.1 1.8 1 1 1 2 2 2 1 von Willebrand factor type A domain Ku_C PF03730.14 KXT07424.1 - 0.011 16.4 0.4 0.043 14.5 0.2 2.2 1 1 1 2 2 2 0 Ku70/Ku80 C-terminal arm EamA PF00892.20 KXT07427.1 - 1.6e-09 38.1 21.6 7.1e-05 23.0 2.9 2.6 2 1 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 KXT07427.1 - 2.4e-09 36.8 0.0 4.2e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 KXT07427.1 - 2.1e-08 33.7 2.3 2.1e-08 33.7 2.3 1.6 2 0 0 2 2 2 1 UAA transporter family TPT PF03151.16 KXT07427.1 - 7.8e-06 25.4 0.5 7.8e-06 25.4 0.5 2.1 2 1 0 2 2 2 1 Triose-phosphate Transporter family Phage_holin_3_6 PF07332.11 KXT07427.1 - 0.084 12.9 0.3 0.084 12.9 0.3 3.4 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Aldo_ket_red PF00248.21 KXT07428.1 - 1.7e-15 57.0 0.0 4.9e-14 52.2 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Ank_2 PF12796.7 KXT07429.1 - 1.4e-39 134.6 1.0 7.6e-15 55.3 0.1 3.5 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXT07429.1 - 3.5e-27 94.4 1.7 1.8e-09 37.9 0.1 4.5 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXT07429.1 - 1.6e-24 85.6 1.8 4.2e-08 33.3 0.5 5.3 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 KXT07429.1 - 3.5e-24 84.1 4.0 3.3e-05 24.1 0.1 6.4 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 KXT07429.1 - 3.8e-23 79.1 1.8 1.1e-06 28.5 0.1 6.1 7 0 0 7 7 7 4 Ankyrin repeat AMP-binding PF00501.28 KXT07430.1 - 1.1e-90 304.3 0.4 1.3e-90 304.0 0.4 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXT07430.1 - 2.5e-27 95.7 0.1 9.7e-25 87.4 0.2 2.7 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KXT07430.1 - 5.3e-19 67.9 0.4 1.4e-18 66.5 0.4 1.8 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus DUF1967 PF09269.11 KXT07430.1 - 0.12 12.4 0.0 0.57 10.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) VPS9 PF02204.18 KXT07431.1 - 1.9e-15 56.9 0.0 4e-15 55.9 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.6 KXT07431.1 - 3.6e-15 55.8 1.0 1.1e-11 44.8 0.0 4.8 5 1 1 6 6 6 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KXT07431.1 - 7.4e-13 48.9 0.3 0.00049 20.6 0.0 4.1 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KXT07431.1 - 4.6e-08 33.5 0.1 0.5 11.0 0.0 5.7 6 0 0 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KXT07431.1 - 0.00013 22.1 0.1 5.7 7.9 0.0 5.9 6 0 0 6 6 6 1 Ankyrin repeat Ank PF00023.30 KXT07431.1 - 0.0015 18.9 0.4 11 6.7 0.0 4.9 5 0 0 5 5 5 1 Ankyrin repeat PX PF00787.24 KXT07431.1 - 0.0037 17.2 0.0 0.012 15.5 0.0 1.9 1 0 0 1 1 1 1 PX domain adh_short_C2 PF13561.6 KXT07432.1 - 0.14 11.7 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase NTF2 PF02136.20 KXT07436.1 - 2.7e-27 95.7 1.7 5.1e-27 94.8 1.7 1.5 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain EB1 PF03271.17 KXT07436.1 - 1.2e-16 60.6 1.1 3e-16 59.3 1.1 1.7 1 0 0 1 1 1 1 EB1-like C-terminal motif RRM_1 PF00076.22 KXT07436.1 - 2.3e-08 33.7 0.2 4.7e-08 32.7 0.2 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CH PF00307.31 KXT07436.1 - 0.00044 20.4 0.3 0.0021 18.2 0.1 2.2 2 0 0 2 2 2 1 Calponin homology (CH) domain Cep57_MT_bd PF06657.13 KXT07437.1 - 2.4e-25 88.7 0.5 2.4e-25 88.7 0.5 5.3 5 0 0 5 5 5 2 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.6 KXT07437.1 - 1.6e-06 28.1 5.3 1.6e-06 28.1 5.3 4.1 2 1 1 3 3 3 1 Centrosome localisation domain of PPC89 TSC22 PF01166.18 KXT07437.1 - 0.025 14.9 1.4 0.025 14.9 1.4 4.4 4 1 1 5 5 5 0 TSC-22/dip/bun family Rootletin PF15035.6 KXT07437.1 - 0.46 10.5 23.3 0.013 15.6 10.9 3.4 3 0 0 3 3 3 0 Ciliary rootlet component, centrosome cohesion DUF4618 PF15397.6 KXT07437.1 - 0.8 9.1 10.4 0.41 10.0 2.6 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4618) Erp_C PF06780.11 KXT07437.1 - 0.8 9.7 4.2 1.9 8.5 0.1 3.0 3 0 0 3 3 3 0 Erp protein C-terminus BLOC1_2 PF10046.9 KXT07437.1 - 3.6 8.0 9.5 9.4 6.6 0.4 3.2 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CENP-F_leu_zip PF10473.9 KXT07437.1 - 4.4 7.3 21.7 1.1 9.2 7.4 3.7 3 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 JIP_LZII PF16471.5 KXT07437.1 - 4.7 7.5 15.3 0.13 12.4 2.2 3.8 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II WD40_alt PF14077.6 KXT07437.1 - 4.9 7.1 6.4 2.5 8.0 0.2 3.5 3 0 0 3 3 3 0 Alternative WD40 repeat motif Shugoshin_N PF07558.11 KXT07437.1 - 5.4 7.0 5.9 0.89 9.5 0.3 2.7 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region KASH_CCD PF14662.6 KXT07437.1 - 8.1 6.2 21.7 5.1 6.9 1.4 3.4 2 1 0 3 3 3 0 Coiled-coil region of CCDC155 or KASH VHS PF00790.19 KXT07440.1 - 2.7e-26 92.1 0.0 5.4e-26 91.1 0.0 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 KXT07440.1 - 2.7e-05 24.4 0.2 6.6e-05 23.1 0.2 1.7 1 0 0 1 1 1 1 GAT domain MSA-2c PF12238.8 KXT07440.1 - 0.02 14.9 13.8 0.5 10.3 5.7 2.4 2 0 0 2 2 2 0 Merozoite surface antigen 2c F1F0-ATPsyn_F PF10791.9 KXT07440.1 - 0.17 12.4 0.3 0.52 10.8 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial F1-F0 ATP synthase subunit F of fungi LIM_bind PF01803.16 KXT07442.1 - 5.6e-63 212.7 0.3 5.6e-63 212.7 0.3 5.2 3 1 1 4 4 4 1 LIM-domain binding protein RTA1 PF04479.13 KXT07443.1 - 4.2e-12 46.1 1.7 1.2e-11 44.7 0.1 1.9 1 1 1 2 2 2 2 RTA1 like protein BUD22 PF09073.10 KXT07444.1 - 1.7e-83 281.4 24.8 2e-83 281.2 24.8 1.0 1 0 0 1 1 1 1 BUD22 BORCS7 PF16088.5 KXT07445.1 - 0.016 15.4 1.0 0.18 12.1 0.3 2.5 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 7 PH PF00169.29 KXT07445.1 - 0.033 14.7 0.0 0.076 13.5 0.0 1.6 1 0 0 1 1 1 0 PH domain eRF1_3 PF03465.15 KXT07445.1 - 0.072 13.6 0.0 0.24 11.9 0.0 1.8 1 0 0 1 1 1 0 eRF1 domain 3 DUF3106 PF11304.8 KXT07445.1 - 0.081 13.4 0.3 0.33 11.4 0.3 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) HTH_38 PF13936.6 KXT07446.1 - 0.021 14.6 2.0 0.29 10.9 0.0 3.0 2 1 0 2 2 2 0 Helix-turn-helix domain Recombinase PF07508.13 KXT07446.1 - 0.023 15.1 0.7 8.5 6.8 0.0 2.4 1 1 1 2 2 2 0 Recombinase LysM PF01476.20 KXT07446.1 - 0.12 12.5 0.1 1.3 9.2 0.0 2.5 3 0 0 3 3 3 0 LysM domain ATP-synt_ab PF00006.25 KXT07447.1 - 3.9e-67 226.0 0.0 5.6e-67 225.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KXT07447.1 - 6e-14 52.3 0.6 1.2e-13 51.3 0.6 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain VHS PF00790.19 KXT07448.1 - 2.6e-33 114.9 0.0 5.2e-33 113.9 0.0 1.6 1 0 0 1 1 1 1 VHS domain Myb_DNA-bind_2 PF08914.11 KXT07448.1 - 1.4e-17 63.6 1.6 2.7e-17 62.7 0.5 2.1 2 0 0 2 2 2 1 Rap1 Myb domain Rap1_C PF11626.8 KXT07448.1 - 9.4e-17 60.9 0.4 1e-15 57.6 0.0 2.8 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain SH3_1 PF00018.28 KXT07448.1 - 3.2e-16 58.7 0.0 7.1e-16 57.6 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KXT07448.1 - 4e-14 52.2 0.1 8.4e-14 51.2 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KXT07448.1 - 1.3e-12 47.2 0.0 2.5e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain BRCT_2 PF16589.5 KXT07448.1 - 1.6e-08 34.9 0.0 3.5e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain GAT PF03127.14 KXT07448.1 - 5.7e-08 32.9 0.0 1.6e-07 31.5 0.0 1.9 1 0 0 1 1 1 1 GAT domain Rap1-DNA-bind PF09197.10 KXT07448.1 - 8.9e-05 23.1 0.9 0.0013 19.3 0.4 3.1 2 1 0 2 2 2 1 Rap1, DNA-binding UIM PF02809.20 KXT07448.1 - 0.024 14.5 3.1 0.11 12.4 3.1 2.3 1 0 0 1 1 1 0 Ubiquitin interaction motif zf-Di19 PF05605.12 KXT07449.1 - 0.029 14.6 0.0 0.057 13.7 0.0 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.6 KXT07449.1 - 0.044 13.7 0.2 0.17 11.8 0.1 2.0 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.6 KXT07449.1 - 0.055 14.3 0.1 0.18 12.7 0.1 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger HIT PF01230.23 KXT07451.1 - 2.1e-17 63.6 0.0 4.4e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KXT07451.1 - 0.007 16.8 0.5 0.14 12.6 0.5 2.3 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF747 PF05346.11 KXT07452.1 - 1.2e-120 402.8 4.1 1.5e-120 402.5 4.1 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family WD40 PF00400.32 KXT07453.1 - 7.1e-23 80.5 7.7 1e-05 26.1 0.0 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat F-box-like PF12937.7 KXT07453.1 - 1.2e-11 44.3 0.1 2.7e-11 43.2 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXT07453.1 - 3.4e-09 36.4 0.1 1.1e-08 34.8 0.1 1.9 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 KXT07453.1 - 4.8e-06 25.5 0.2 0.0089 14.7 0.0 3.2 2 1 1 3 3 3 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KXT07453.1 - 3.8e-05 23.9 0.2 1.1 9.7 0.0 3.7 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KXT07453.1 - 0.00067 19.3 0.1 0.0059 16.2 0.1 2.4 1 1 1 2 2 2 1 PQQ-like domain WD40_like PF17005.5 KXT07453.1 - 0.01 15.2 0.3 0.71 9.1 0.1 3.2 2 2 1 3 3 3 0 WD40-like domain PQQ PF01011.21 KXT07453.1 - 0.072 13.1 0.0 2.5 8.2 0.0 3.1 2 0 0 2 2 2 0 PQQ enzyme repeat PQQ_3 PF13570.6 KXT07453.1 - 3.5 8.3 5.0 45 4.7 0.0 4.5 4 2 0 4 4 4 0 PQQ-like domain YchF-GTPase_C PF06071.13 KXT07455.1 - 1.9e-34 117.7 0.1 6e-34 116.1 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KXT07455.1 - 9.6e-15 54.7 0.0 3.7e-14 52.8 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KXT07455.1 - 0.0069 15.9 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 KXT07455.1 - 0.0087 16.1 0.2 0.027 14.5 0.1 1.9 2 0 0 2 2 2 1 TGS domain Dynamin_N PF00350.23 KXT07455.1 - 0.089 12.8 0.0 0.35 10.9 0.0 2.0 2 1 0 2 2 2 0 Dynamin family DUF3721 PF12518.8 KXT07455.1 - 0.098 12.5 1.0 0.22 11.4 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function Glyco_tranf_2_5 PF13712.6 KXT07455.1 - 0.16 11.6 0.3 2.7 7.6 0.0 2.3 2 0 0 2 2 2 0 Glycosyltransferase like family Mus7 PF09462.10 KXT07456.1 - 3.8e-127 425.7 9.4 6.1e-127 425.0 9.4 1.3 1 0 0 1 1 1 1 Mus7/MMS22 family Tetraspanin PF00335.20 KXT07456.1 - 0.012 15.3 1.2 0.029 14.1 0.2 1.9 1 1 1 2 2 2 0 Tetraspanin family BAR_3 PF16746.5 KXT07456.1 - 0.57 9.9 5.7 0.6 9.8 2.7 2.5 2 0 0 2 2 2 0 BAR domain of APPL family MFS_1 PF07690.16 KXT07457.1 - 1.1e-36 126.6 31.3 1.9e-36 125.7 31.3 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF604 PF04646.12 KXT07459.1 - 6.4e-09 35.6 0.0 1.4e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.16 KXT07459.1 - 2.3e-07 30.5 0.0 3.8e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Fringe-like IPU_b_solenoid PF18783.1 KXT07460.1 - 0.058 13.4 0.2 0.52 10.4 0.0 2.3 2 0 0 2 2 2 0 Isopullulanase beta-solenoid repeat Abhydro_lipase PF04083.16 KXT07462.1 - 5.8e-19 67.4 0.0 1.3e-18 66.3 0.0 1.7 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 KXT07462.1 - 6.5e-08 32.5 0.0 1.5e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXT07462.1 - 0.01 15.1 0.0 0.027 13.7 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KXT07463.1 - 8e-30 104.3 0.0 2.3e-22 79.9 0.0 2.9 3 0 0 3 3 3 2 alpha/beta hydrolase fold HMG_box PF00505.19 KXT07463.1 - 1.2e-21 76.9 0.6 2.8e-21 75.7 0.6 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KXT07463.1 - 2.3e-06 28.1 0.2 4.7e-06 27.1 0.2 1.5 1 0 0 1 1 1 1 HMG-box domain DUF4484 PF14831.6 KXT07463.1 - 0.49 10.4 4.3 0.11 12.6 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) APH PF01636.23 KXT07464.1 - 3.5e-13 50.0 0.1 5.7e-13 49.4 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KXT07464.1 - 3.9e-07 29.3 0.0 5.2e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.20 KXT07464.1 - 2.2e-06 27.2 0.0 4.7e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 KXT07464.1 - 0.00052 19.7 0.0 0.00083 19.0 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Glyco_transf_34 PF05637.12 KXT07466.1 - 1.3e-68 231.3 0.0 1.5e-68 231.1 0.0 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family TMEM208_SND2 PF05620.11 KXT07466.1 - 0.16 11.8 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 GFO_IDH_MocA PF01408.22 KXT07469.1 - 3.5e-09 37.5 0.3 1.7e-08 35.3 0.3 2.0 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold TrmO_C PF18389.1 KXT07470.1 - 0.072 13.2 0.4 0.19 11.8 0.4 1.8 1 0 0 1 1 1 0 TrmO C-terminal domain ERF PF04404.12 KXT07471.1 - 0.83 9.5 3.7 13 5.6 1.3 2.6 2 1 0 2 2 2 0 ERF superfamily Frataxin_Cyay PF01491.16 KXT07473.1 - 3.3e-37 126.9 0.0 4.4e-37 126.4 0.0 1.2 1 0 0 1 1 1 1 Frataxin-like domain BiPBP_C PF06832.12 KXT07473.1 - 0.004 17.2 0.0 0.0075 16.3 0.0 1.5 1 0 0 1 1 1 1 Penicillin-Binding Protein C-terminus Family 2OG-FeII_Oxy_2 PF13532.6 KXT07474.1 - 6.7e-32 111.3 0.0 1.2e-31 110.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SPX PF03105.19 KXT07475.1 - 2.3e-41 143.0 13.0 3e-28 99.8 8.6 2.2 1 1 1 2 2 2 2 SPX domain Na_sulph_symp PF00939.19 KXT07475.1 - 3.2e-31 108.9 38.4 4.6e-31 108.4 38.4 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 KXT07475.1 - 3.6e-26 92.1 69.0 1.3e-24 87.0 40.4 2.3 2 1 1 3 3 3 2 Citrate transporter Hpt PF01627.23 KXT07476.1 - 1.1e-10 41.7 0.1 2.1e-10 40.7 0.1 1.6 1 1 0 1 1 1 1 Hpt domain FH2 PF02181.23 KXT07476.1 - 0.21 10.7 4.8 0.21 10.7 1.1 1.9 1 1 1 2 2 2 0 Formin Homology 2 Domain Hpt PF01627.23 KXT07477.1 - 1.1e-10 41.7 0.1 2.1e-10 40.7 0.1 1.6 1 1 0 1 1 1 1 Hpt domain FH2 PF02181.23 KXT07477.1 - 0.21 10.7 4.8 0.21 10.7 1.1 1.9 1 1 1 2 2 2 0 Formin Homology 2 Domain Hpt PF01627.23 KXT07478.1 - 1.1e-10 41.7 0.1 2.1e-10 40.7 0.1 1.6 1 1 0 1 1 1 1 Hpt domain FH2 PF02181.23 KXT07478.1 - 0.21 10.7 4.8 0.21 10.7 1.1 1.9 1 1 1 2 2 2 0 Formin Homology 2 Domain AdoHcyase PF05221.17 KXT07479.1 - 2.9e-124 414.1 0.0 2.1e-73 247.1 0.1 3.0 2 1 1 3 3 3 3 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 KXT07479.1 - 2.6e-85 284.5 1.9 4e-85 283.9 1.9 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KXT07479.1 - 1.4e-07 31.0 0.1 3e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KXT07479.1 - 0.0004 20.0 0.2 0.00065 19.3 0.2 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 KXT07479.1 - 0.0023 18.2 0.0 0.0057 16.9 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain Oxidored_nitro PF00148.19 KXT07479.1 - 0.015 14.0 0.2 0.2 10.3 0.0 2.1 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase ELFV_dehydrog PF00208.21 KXT07479.1 - 0.053 13.2 0.1 0.099 12.3 0.1 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Aminotran_3 PF00202.21 KXT07480.1 - 1.1e-112 376.7 0.0 1.4e-112 376.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KXT07480.1 - 0.0003 20.1 0.0 0.00091 18.5 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class I and II NHase_beta PF02211.15 KXT07480.1 - 0.18 11.8 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Nitrile hydratase beta subunit PAP2 PF01569.21 KXT07481.1 - 1e-26 93.3 1.8 1e-26 93.3 1.8 2.6 2 1 0 2 2 2 1 PAP2 superfamily DUF389 PF04087.14 KXT07481.1 - 0.026 14.5 0.7 0.34 11.0 0.0 2.8 2 1 2 4 4 4 0 Domain of unknown function (DUF389) SNAP PF14938.6 KXT07482.1 - 1.2e-114 382.6 19.4 1.3e-114 382.4 19.4 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 KXT07482.1 - 7.4e-07 29.4 15.3 0.023 15.0 0.6 3.8 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 KXT07482.1 - 0.00015 21.5 12.5 0.62 10.2 0.1 5.6 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 KXT07482.1 - 0.0051 17.4 17.0 15 6.5 0.5 6.2 4 1 2 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 KXT07482.1 - 0.013 15.5 19.4 1.1 9.6 0.2 6.0 4 2 3 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 KXT07482.1 - 0.18 12.1 0.5 0.18 12.1 0.5 5.4 5 2 1 6 6 5 0 Tetratricopeptide repeat His_Phos_2 PF00328.22 KXT07482.1 - 0.2 11.0 5.2 0.038 13.3 1.4 1.6 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 2) PhoU PF01895.19 KXT07482.1 - 0.66 10.5 6.4 3 8.4 2.3 3.1 2 1 0 2 2 2 0 PhoU domain SMBP PF16785.5 KXT07482.1 - 4.3 7.6 11.5 0.083 13.1 3.7 2.2 3 1 0 3 3 3 0 Small metal-binding protein TPR_14 PF13428.6 KXT07482.1 - 4.7 8.3 14.6 6.5 7.8 0.4 5.5 2 1 3 6 6 6 0 Tetratricopeptide repeat NSF PF02071.20 KXT07482.1 - 6 8.1 19.6 5.7 8.2 0.1 7.1 7 1 0 7 7 7 0 Aromatic-di-Alanine (AdAR) repeat TPR_1 PF00515.28 KXT07482.1 - 7.3 6.6 15.7 12 5.9 0.6 5.6 4 2 1 5 5 5 0 Tetratricopeptide repeat GAS2 PF02187.17 KXT07483.1 - 3.8e-06 26.9 0.0 9.3e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain DUF4795 PF16043.5 KXT07483.1 - 0.032 13.9 0.0 5.1 6.6 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) CrgA PF06781.12 KXT07484.1 - 0.79 9.8 3.4 0.59 10.2 0.3 2.3 2 0 0 2 2 2 0 Cell division protein CrgA WD40 PF00400.32 KXT07485.1 - 5.9e-19 68.1 0.3 0.0029 18.4 0.0 8.3 9 0 0 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXT07485.1 - 0.00016 21.9 0.3 6.4 7.1 0.0 5.0 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Neur_chan_memb PF02932.16 KXT07485.1 - 0.021 14.9 0.6 0.042 13.9 0.6 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region bZIP_1 PF00170.21 KXT07486.1 - 0.00025 21.1 13.8 0.0004 20.4 13.8 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXT07486.1 - 0.028 14.5 6.9 0.028 14.5 6.9 2.0 1 1 1 2 2 2 0 Basic region leucine zipper DUF1192 PF06698.11 KXT07486.1 - 0.085 12.9 0.5 0.19 11.8 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) bZIP_1 PF00170.21 KXT07487.1 - 0.00051 20.1 13.8 0.00096 19.2 13.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor PAP1 PF08601.10 KXT07487.1 - 0.0041 16.9 1.2 2.8 7.6 1.5 2.1 2 0 0 2 2 2 2 Transcription factor PAP1 DUF1192 PF06698.11 KXT07487.1 - 0.27 11.3 2.6 0.4 10.8 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) bZIP_2 PF07716.15 KXT07487.1 - 0.85 9.8 12.9 0.062 13.4 6.9 2.0 1 1 1 2 2 2 0 Basic region leucine zipper bZIP_1 PF00170.21 KXT07488.1 - 0.00051 20.1 13.8 0.00096 19.2 13.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor PAP1 PF08601.10 KXT07488.1 - 0.0041 16.9 1.2 2.8 7.6 1.5 2.1 2 0 0 2 2 2 2 Transcription factor PAP1 DUF1192 PF06698.11 KXT07488.1 - 0.27 11.3 2.6 0.4 10.8 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) bZIP_2 PF07716.15 KXT07488.1 - 0.85 9.8 12.9 0.062 13.4 6.9 2.0 1 1 1 2 2 2 0 Basic region leucine zipper ADH_N PF08240.12 KXT07490.1 - 2e-23 82.3 5.9 3.4e-23 81.6 5.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXT07490.1 - 1.5e-13 50.9 0.1 2.5e-12 46.9 0.0 2.5 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXT07490.1 - 0.002 19.2 0.0 0.0069 17.4 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KXT07490.1 - 0.003 16.9 0.0 0.0065 15.8 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KXT07490.1 - 0.0058 16.0 0.0 0.0099 15.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Gp_dh_N PF00044.24 KXT07490.1 - 0.09 13.1 0.0 1.2 9.5 0.0 2.4 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ADH_N PF08240.12 KXT07491.1 - 2e-23 82.3 5.9 3.4e-23 81.6 5.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXT07491.1 - 1.5e-13 50.9 0.1 2.5e-12 46.9 0.0 2.5 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXT07491.1 - 0.002 19.2 0.0 0.0069 17.4 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KXT07491.1 - 0.003 16.9 0.0 0.0065 15.8 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KXT07491.1 - 0.0058 16.0 0.0 0.0099 15.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Gp_dh_N PF00044.24 KXT07491.1 - 0.09 13.1 0.0 1.2 9.5 0.0 2.4 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DUF3535 PF12054.8 KXT07492.1 - 1.2e-119 400.4 1.4 1.2e-118 397.1 0.7 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 KXT07492.1 - 1.2e-62 211.7 0.0 2.5e-62 210.7 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KXT07492.1 - 1.1e-19 70.8 0.4 9e-19 67.9 0.0 2.7 4 0 0 4 4 4 1 Helicase conserved C-terminal domain HEAT PF02985.22 KXT07492.1 - 9.7e-15 53.4 13.9 0.011 16.0 0.0 10.7 11 0 0 11 11 11 4 HEAT repeat Vac14_Fab1_bd PF12755.7 KXT07492.1 - 5.8e-07 30.0 0.0 0.0073 16.9 0.0 3.8 3 1 0 3 3 3 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 KXT07492.1 - 5.2e-05 23.6 18.5 0.0086 16.4 0.1 7.6 9 1 0 9 9 9 1 HEAT repeats CLASP_N PF12348.8 KXT07492.1 - 0.00039 20.1 0.1 5.1 6.6 0.0 4.0 2 2 1 3 3 3 2 CLASP N terminal TAF6_C PF07571.13 KXT07492.1 - 0.0022 18.3 0.0 1.6 9.1 0.0 4.8 5 0 0 5 5 5 1 TAF6 C-terminal HEAT repeat domain ERCC3_RAD25_C PF16203.5 KXT07492.1 - 0.14 11.4 0.0 0.29 10.3 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase AMP-binding PF00501.28 KXT07493.1 - 1.3e-66 225.0 0.2 1.6e-66 224.7 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXT07493.1 - 3.8e-18 66.2 0.0 1.1e-17 64.7 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain bZIP_1 PF00170.21 KXT07494.1 - 2.5e-05 24.3 9.0 4.1e-05 23.6 9.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KXT07494.1 - 0.019 15.1 9.4 0.04 14.0 9.4 1.5 1 0 0 1 1 1 0 Basic region leucine zipper Mit_KHE1 PF10173.9 KXT07494.1 - 0.12 12.4 0.8 0.22 11.6 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related DUF4407 PF14362.6 KXT07494.1 - 3.4 6.9 5.4 5.6 6.2 5.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Stm1_N PF09598.10 KXT07495.1 - 7.1e-18 65.2 3.1 7.1e-18 65.2 3.1 3.5 4 0 0 4 4 4 1 Stm1 CDH-cyt PF16010.5 KXT07496.1 - 3e-25 89.0 2.4 3e-25 89.0 2.4 1.7 2 0 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase DOMON PF03351.17 KXT07496.1 - 0.00015 22.0 0.3 0.00027 21.1 0.3 1.4 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.16 KXT07496.1 - 0.022 14.9 9.7 0.042 14.0 9.7 1.5 1 0 0 1 1 1 0 Eukaryotic cytochrome b561 stn_TNFRSF12A PF12191.8 KXT07496.1 - 0.083 13.1 2.8 1.4 9.1 0.0 3.0 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Phage_holin_3_6 PF07332.11 KXT07496.1 - 0.86 9.7 10.0 0.8 9.8 0.2 2.5 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Ank_2 PF12796.7 KXT07497.1 - 1.5e-11 44.7 0.6 2.2e-06 28.1 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXT07497.1 - 2.6e-09 36.5 0.0 0.00057 20.1 0.0 3.6 3 1 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KXT07497.1 - 1.8e-08 34.7 0.0 1.6e-07 31.7 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KXT07497.1 - 2.1e-07 31.1 0.1 0.00062 20.0 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KXT07497.1 - 1.6e-06 28.3 0.0 0.08 13.4 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat VWA_2 PF13519.6 KXT07497.1 - 0.013 16.2 0.1 0.34 11.6 0.0 2.7 2 1 1 3 3 3 0 von Willebrand factor type A domain zf-C3HC PF07967.13 KXT07498.1 - 9.4e-39 132.5 3.0 9.9e-30 103.3 0.3 2.3 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 KXT07498.1 - 8.5e-18 64.3 0.1 8.5e-18 64.3 0.1 2.6 3 1 0 3 3 3 1 Rsm1-like Tim17 PF02466.19 KXT07499.1 - 4.2e-32 110.8 7.6 5.5e-32 110.5 7.6 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Peptidase_S10 PF00450.22 KXT07501.1 - 7.2e-83 279.3 0.9 1.3e-82 278.5 0.9 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase Adeno_IVa2 PF02456.15 KXT07501.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein ADH_N PF08240.12 KXT07502.1 - 5.2e-28 97.1 2.4 7.6e-28 96.6 1.5 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXT07502.1 - 6.7e-24 84.3 0.0 1.3e-23 83.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXT07502.1 - 2.9e-07 30.2 0.0 4.4e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KXT07502.1 - 3.9e-06 28.0 0.0 6.8e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 KXT07502.1 - 0.0013 18.6 0.3 0.0042 17.0 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated TrkA_N PF02254.18 KXT07502.1 - 0.0074 16.5 0.0 0.014 15.7 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Pyr_redox PF00070.27 KXT07502.1 - 0.02 15.5 0.0 0.055 14.0 0.0 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF4434 PF14488.6 KXT07502.1 - 0.19 11.7 0.0 0.29 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) Ribosomal_L3 PF00297.22 KXT07503.1 - 3.6e-186 618.5 11.0 5.1e-186 618.0 11.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L3 CwfJ_C_2 PF04676.14 KXT07503.1 - 0.017 16.0 2.3 0.03 15.2 1.0 2.1 2 0 0 2 2 2 0 Protein similar to CwfJ C-terminus 2 DUF4269 PF14091.6 KXT07503.1 - 0.06 13.6 0.5 0.13 12.5 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4269) MAPEG PF01124.18 KXT07526.1 - 1.9e-17 63.4 0.3 2.1e-17 63.2 0.3 1.0 1 0 0 1 1 1 1 MAPEG family motB PF17613.2 KXT07526.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.3 1 1 0 1 1 1 0 Modifier of transcription DUF1771 PF08590.10 KXT07527.1 - 1.5e-14 54.1 12.3 1.5e-14 54.1 12.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) zf-CCCH PF00642.24 KXT07527.1 - 3.1e-10 39.7 2.8 0.00011 22.1 0.4 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KXT07527.1 - 1.3e-09 37.8 10.1 2e-06 27.7 1.0 2.9 2 1 0 2 2 2 2 Zinc finger domain zf-CCCH_2 PF14608.6 KXT07527.1 - 3.3e-06 27.4 5.6 0.0082 16.6 0.3 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Smr PF01713.21 KXT07527.1 - 4.6e-06 26.9 0.0 6.2e-05 23.3 0.0 2.7 3 0 0 3 3 3 1 Smr domain zf-CCCH_4 PF18044.1 KXT07527.1 - 1.4e-05 24.8 0.4 1.4e-05 24.8 0.4 2.9 2 1 0 2 2 2 1 CCCH-type zinc finger Torus PF16131.5 KXT07527.1 - 0.0078 16.9 5.1 0.35 11.6 0.5 2.5 1 1 1 2 2 2 2 Torus domain zf-CCCH_3 PF15663.5 KXT07527.1 - 0.026 14.7 3.5 0.26 11.5 3.5 2.4 1 1 0 1 1 1 0 Zinc-finger containing family TraB PF01963.17 KXT07527.1 - 0.13 12.2 4.3 0.072 13.0 0.4 2.2 2 0 0 2 2 2 0 TraB family zf-C3H1 PF10650.9 KXT07527.1 - 0.15 11.8 0.5 7.6 6.4 0.0 2.3 2 0 0 2 2 2 0 Putative zinc-finger domain zf-CCCH PF00642.24 KXT07528.1 - 1.2e-20 72.9 35.3 1.2e-05 25.0 3.8 5.6 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KXT07528.1 - 6.8e-13 48.2 37.0 4.9e-06 26.4 4.6 5.9 6 0 0 6 6 6 5 Zinc finger domain Torus PF16131.5 KXT07528.1 - 2.6e-07 31.3 30.3 0.003 18.2 2.7 5.4 2 1 4 6 6 6 3 Torus domain zf-CCCH_4 PF18044.1 KXT07528.1 - 0.00024 20.8 1.8 0.00024 20.8 1.8 5.8 6 0 0 6 6 6 3 CCCH-type zinc finger zf-CCCH_3 PF15663.5 KXT07528.1 - 0.0075 16.5 12.4 0.54 10.5 2.8 2.7 1 1 1 2 2 2 2 Zinc-finger containing family AA_permease PF00324.21 KXT07530.1 - 1.5e-106 356.9 43.6 1.8e-106 356.6 43.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KXT07530.1 - 1.6e-27 96.4 47.6 2e-27 96.1 47.6 1.0 1 0 0 1 1 1 1 Amino acid permease DUF4781 PF16013.5 KXT07530.1 - 0.23 10.2 1.8 0.42 9.4 1.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) DUF3671 PF12420.8 KXT07530.1 - 8.5 6.5 9.9 1e+02 3.0 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function p450 PF00067.22 KXT07531.1 - 5.7e-31 107.8 0.0 7.5e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Trehalose_PPase PF02358.16 KXT07531.1 - 0.18 10.9 0.0 0.31 10.1 0.0 1.3 1 0 0 1 1 1 0 Trehalose-phosphatase zf-C2H2 PF00096.26 KXT07532.1 - 0.00051 20.4 0.5 0.00051 20.4 0.5 3.1 3 1 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXT07532.1 - 0.049 14.5 0.2 0.049 14.5 0.2 3.0 3 1 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KXT07533.1 - 0.0008 19.7 6.3 0.012 16.0 0.0 3.3 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXT07533.1 - 0.025 15.4 3.9 0.11 13.4 0.0 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXT07533.1 - 0.044 14.2 7.1 4.3 7.9 1.5 3.2 3 0 0 3 3 3 0 Zinc-finger double domain DUF3674 PF12426.8 KXT07533.1 - 0.058 13.4 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 RNA dependent RNA polymerase OrsD PF12013.8 KXT07533.1 - 0.12 12.8 7.7 4.1 7.9 0.2 2.7 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D Ogr_Delta PF04606.12 KXT07533.1 - 0.19 11.8 2.5 1.2 9.1 1.7 2.7 2 1 0 2 2 2 0 Ogr/Delta-like zinc finger zf-C2H2 PF00096.26 KXT07534.1 - 0.0008 19.7 6.3 0.012 16.0 0.0 3.3 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KXT07534.1 - 0.025 15.4 3.9 0.11 13.4 0.0 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KXT07534.1 - 0.044 14.2 7.1 4.3 7.9 1.5 3.2 3 0 0 3 3 3 0 Zinc-finger double domain DUF3674 PF12426.8 KXT07534.1 - 0.058 13.4 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 RNA dependent RNA polymerase OrsD PF12013.8 KXT07534.1 - 0.12 12.8 7.7 4.1 7.9 0.2 2.7 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D Ogr_Delta PF04606.12 KXT07534.1 - 0.19 11.8 2.5 1.2 9.1 1.7 2.7 2 1 0 2 2 2 0 Ogr/Delta-like zinc finger WD40 PF00400.32 KXT07535.1 - 4e-51 169.9 17.5 6.3e-06 26.8 0.1 11.6 11 1 0 11 11 11 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXT07535.1 - 9.1e-16 57.9 6.9 0.00091 19.5 0.0 9.4 5 2 4 10 10 10 6 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 KXT07535.1 - 4.8e-15 55.8 0.0 1e-14 54.8 0.0 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 KXT07535.1 - 1e-12 47.7 3.1 0.059 12.3 0.0 7.3 3 2 5 8 8 8 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KXT07535.1 - 3.5e-07 29.3 6.1 1 7.9 0.0 5.9 5 1 1 6 6 6 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KXT07535.1 - 0.00026 19.9 0.8 0.8 8.4 0.0 4.1 3 2 1 4 4 4 2 Nup133 N terminal like WD40_like PF17005.5 KXT07535.1 - 0.0036 16.7 0.0 2.1 7.6 0.0 3.5 3 1 0 3 3 3 1 WD40-like domain Hira PF07569.11 KXT07535.1 - 0.072 12.8 1.2 5.2 6.7 0.0 3.8 4 1 1 5 5 5 0 TUP1-like enhancer of split Cation_efflux PF01545.21 KXT07537.1 - 9.7e-53 178.9 2.4 2.9e-52 177.3 2.4 1.7 1 1 0 1 1 1 1 Cation efflux family R3H-assoc PF13902.6 KXT07538.1 - 3.2e-26 92.3 7.3 3.2e-26 92.3 7.3 2.2 2 0 0 2 2 2 1 R3H-associated N-terminal domain R3H PF01424.22 KXT07538.1 - 0.00099 19.1 0.2 0.014 15.4 0.0 2.7 2 0 0 2 2 2 1 R3H domain Med8 PF10232.9 KXT07538.1 - 0.72 9.4 6.6 0.46 10.0 1.2 2.2 2 0 0 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 Pkinase PF00069.25 KXT07539.1 - 2.4e-65 220.6 0.2 2.8e-65 220.3 0.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KXT07539.1 - 6.3e-19 68.3 0.0 9.3e-19 67.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KXT07539.1 - 2.5e-07 30.9 0.0 1.5e-05 25.0 0.2 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KXT07539.1 - 0.0042 15.9 0.0 0.0088 14.9 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KXT07539.1 - 0.0044 16.4 0.0 0.006 15.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KXT07539.1 - 0.01 15.2 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KXT07539.1 - 0.026 14.1 1.5 0.036 13.6 0.2 2.0 2 0 0 2 2 2 0 Choline/ethanolamine kinase Methyltransf_23 PF13489.6 KXT07540.1 - 1.1e-09 38.3 0.0 1.7e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KXT07540.1 - 0.00095 19.8 0.1 0.017 15.8 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXT07540.1 - 0.027 15.1 0.0 0.16 12.6 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KXT07540.1 - 0.034 14.9 0.0 0.17 12.6 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Nucleoporin_N PF08801.11 KXT07541.1 - 1.9e-77 260.8 0.0 2.7e-77 260.4 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 KXT07541.1 - 9.4e-43 146.8 2.2 1.5e-42 146.1 2.2 1.3 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal PHC2_SAM_assoc PF16616.5 KXT07542.1 - 3.3 8.5 9.0 5.6 7.8 9.0 1.4 1 0 0 1 1 1 0 Unstructured region on Polyhomeotic-like protein 1 and 2 AC_N PF16214.5 KXT07542.1 - 9.2 5.3 10.2 12 4.9 10.2 1.3 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Amidase PF01425.21 KXT07543.1 - 1.5e-68 231.8 0.0 3.6e-68 230.6 0.0 1.6 1 1 0 1 1 1 1 Amidase BTB PF00651.31 KXT07544.1 - 1.2e-05 25.5 0.0 2.4e-05 24.5 0.0 1.5 1 1 0 1 1 1 1 BTB/POZ domain Glycos_transf_4 PF00953.21 KXT07546.1 - 5.6e-31 107.7 10.1 5.6e-31 107.7 10.1 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 4 DUF2070 PF09843.9 KXT07546.1 - 5.1 5.3 6.7 3.8 5.7 5.4 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) MRP_L53 PF10780.9 KXT07547.1 - 5.4e-17 61.7 0.2 1.4e-16 60.4 0.2 1.7 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 DUF2781 PF10914.8 KXT07548.1 - 2e-41 141.9 12.9 2e-41 141.9 12.9 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2781) DUF2781 PF10914.8 KXT07549.1 - 2e-45 154.8 13.8 2e-45 154.8 13.8 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2781) ECH_1 PF00378.20 KXT07551.1 - 4.8e-57 193.1 0.0 6.9e-57 192.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KXT07551.1 - 2.3e-27 96.4 0.0 1.4e-23 83.9 0.0 2.2 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Rhodanese PF00581.20 KXT07551.1 - 3.3e-11 43.6 0.0 7.4e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain PWI PF01480.17 KXT07552.1 - 4.9e-10 39.6 0.1 1.1e-09 38.5 0.1 1.6 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.22 KXT07552.1 - 0.0019 18.0 0.0 0.004 16.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peroxidase_2 PF01328.17 KXT07553.1 - 4.6e-51 174.0 0.0 5.9e-51 173.7 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 p450 PF00067.22 KXT07554.1 - 5.7e-39 134.1 0.0 9.4e-39 133.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 TPR_14 PF13428.6 KXT07555.1 - 0.033 15.0 4.0 25 6.0 0.1 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat DsrC PF04358.13 KXT07555.1 - 0.06 13.9 0.7 0.66 10.5 0.2 2.6 3 0 0 3 3 3 0 DsrC like protein TPR_14 PF13428.6 KXT07556.1 - 0.031 15.1 5.3 18 6.5 0.1 4.6 4 2 0 4 4 4 0 Tetratricopeptide repeat P-mevalo_kinase PF04275.14 KXT07558.1 - 2.2e-21 76.0 0.0 4.5e-21 74.9 0.0 1.6 1 0 0 1 1 1 1 Phosphomevalonate kinase FAD_binding_4 PF01565.23 KXT07558.1 - 1.1e-17 64.0 1.3 4e-17 62.3 1.4 1.9 2 0 0 2 2 2 1 FAD binding domain Pribosyltran PF00156.27 KXT07558.1 - 2.9e-14 52.9 0.0 6.7e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KXT07558.1 - 0.00012 21.6 0.1 0.00031 20.3 0.0 1.6 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 KXT07558.1 - 0.00095 18.7 0.1 0.0025 17.3 0.0 1.7 2 0 0 2 2 2 1 Phosphoribosyl transferase CPT PF07931.12 KXT07558.1 - 0.018 14.9 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Rab5ip PF07019.12 KXT07559.1 - 2.4e-26 92.2 7.2 2.8e-26 91.9 7.2 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Rab5ip PF07019.12 KXT07560.1 - 2.4e-26 92.2 7.2 2.8e-26 91.9 7.2 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) zf-MYND PF01753.18 KXT07561.1 - 0.0019 18.3 11.8 0.0036 17.4 11.8 1.5 1 0 0 1 1 1 1 MYND finger DUF4259 PF14078.6 KXT07561.1 - 0.05 14.3 0.4 0.1 13.3 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4259) DUF4259 PF14078.6 KXT07562.1 - 0.048 14.4 0.2 0.13 13.0 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4259) DUF4259 PF14078.6 KXT07563.1 - 0.04 14.7 0.4 0.084 13.6 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4259) AA_permease_2 PF13520.6 KXT07565.1 - 9.3e-54 182.9 43.6 1.9e-53 181.9 43.6 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KXT07565.1 - 9e-32 110.3 30.5 9e-32 110.3 30.5 1.4 2 0 0 2 2 2 1 Amino acid permease Vezatin PF12632.7 KXT07566.1 - 2.2e-65 220.8 0.0 3.2e-65 220.3 0.0 1.3 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes AI-2E_transport PF01594.16 KXT07566.1 - 0.00021 20.6 2.7 0.00059 19.1 1.0 2.0 2 0 0 2 2 2 1 AI-2E family transporter MAAL_C PF07476.11 KXT07566.1 - 0.15 11.1 0.0 0.34 10.0 0.0 1.5 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus TcdB_toxin_midC PF12255.8 KXT07567.1 - 0.39 10.8 2.5 0.22 11.6 0.3 1.7 2 0 0 2 2 2 0 Insecticide toxin TcdB middle/C-terminal region Prefoldin_2 PF01920.20 KXT07570.1 - 2.3e-27 95.0 7.3 3e-27 94.7 7.3 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF2205 PF10224.9 KXT07570.1 - 0.016 15.2 10.6 0.07 13.1 3.1 2.1 2 0 0 2 2 2 0 Short coiled-coil protein SAS-6_N PF16531.5 KXT07570.1 - 0.043 14.4 0.0 0.071 13.7 0.0 1.6 1 1 0 1 1 1 0 Centriolar protein SAS N-terminal Cep57_MT_bd PF06657.13 KXT07570.1 - 0.093 13.2 0.2 0.093 13.2 0.2 2.4 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF2089 PF09862.9 KXT07570.1 - 0.32 11.1 2.8 0.66 10.0 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2089) GrpE PF01025.19 KXT07570.1 - 3.6 7.2 9.9 0.24 11.0 0.9 2.0 2 0 0 2 2 2 0 GrpE CBFD_NFYB_HMF PF00808.23 KXT07571.1 - 5.6e-29 100.2 1.5 7.7e-29 99.8 1.5 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KXT07571.1 - 1.4e-06 28.7 0.2 1.9e-06 28.2 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 KXT07571.1 - 0.00059 19.8 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 KXT07571.1 - 0.0012 18.8 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated CENP-T_C PF15511.6 KXT07571.1 - 0.0025 17.9 0.0 0.0035 17.4 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID_20kDa PF03847.13 KXT07571.1 - 0.049 14.1 0.1 0.09 13.3 0.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Peptidase_M1 PF01433.20 KXT07572.1 - 4.1e-44 150.7 0.5 6.1e-44 150.2 0.5 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 KXT07572.1 - 1.3e-36 125.1 0.0 2.6e-36 124.1 0.0 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 KXT07572.1 - 5.2e-28 98.5 0.0 8.3e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_MA_2 PF13485.6 KXT07572.1 - 0.033 13.9 0.2 0.2 11.3 0.1 2.2 3 0 0 3 3 3 0 Peptidase MA superfamily TbpB_B_D PF01298.18 KXT07572.1 - 0.055 13.9 0.0 0.096 13.1 0.0 1.4 1 0 0 1 1 1 0 C-lobe and N-lobe beta barrels of Tf-binding protein B Peptidase_M61 PF05299.12 KXT07572.1 - 0.16 12.3 2.0 3.1 8.2 2.0 2.5 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Fungal_trans PF04082.18 KXT07573.1 - 1.6e-27 96.3 0.1 3.2e-27 95.3 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KXT07573.1 - 0.0031 17.6 10.5 0.0063 16.6 10.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pectate_lyase_3 PF12708.7 KXT07576.1 - 6.7e-83 277.8 10.8 1.2e-77 260.6 3.4 3.2 4 0 0 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KXT07576.1 - 0.0016 18.1 0.8 0.037 13.7 0.2 2.7 2 0 0 2 2 2 1 N terminal extension of bacteriophage endosialidase F-box-like PF12937.7 KXT07577.1 - 0.00022 21.0 0.3 0.0011 18.8 0.0 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KXT07577.1 - 0.16 11.9 2.8 0.17 11.8 0.4 2.2 2 1 0 2 2 2 0 F-box domain CaATP_NAI PF12515.8 KXT07577.1 - 0.2 11.3 0.6 1.9 8.1 0.0 2.4 2 0 0 2 2 2 0 Ca2+-ATPase N terminal autoinhibitory domain ADH_zinc_N PF00107.26 KXT07578.1 - 1.7e-25 89.5 0.0 2.7e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KXT07578.1 - 1.5e-14 55.2 0.0 3e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KXT07578.1 - 5.7e-12 45.5 0.0 9.6e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 KXT07578.1 - 1.3e-05 24.8 0.0 2.2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KXT07578.1 - 0.0027 17.1 0.0 0.0042 16.4 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_kinase PF01513.21 KXT07578.1 - 0.039 13.1 0.1 0.2 10.8 0.0 2.0 2 1 1 3 3 3 0 ATP-NAD kinase TrkA_N PF02254.18 KXT07578.1 - 0.066 13.5 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Asp_decarbox PF02261.16 KXT07578.1 - 0.097 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Aspartate decarboxylase Dynamitin PF04912.14 KXT07579.1 - 5.1e-62 210.4 29.5 1.1e-61 209.3 29.5 1.5 1 1 0 1 1 1 1 Dynamitin PspA_IM30 PF04012.12 KXT07579.1 - 0.0021 17.7 18.2 0.092 12.3 0.4 3.2 3 0 0 3 3 3 2 PspA/IM30 family Rx_N PF18052.1 KXT07579.1 - 0.015 15.5 1.5 0.015 15.5 1.5 2.6 3 0 0 3 3 3 0 Rx N-terminal domain DUF724 PF05266.14 KXT07579.1 - 0.035 13.9 0.2 0.035 13.9 0.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF724) XhlA PF10779.9 KXT07579.1 - 0.057 13.6 0.5 0.057 13.6 0.5 3.6 4 0 0 4 4 3 0 Haemolysin XhlA DUF2203 PF09969.9 KXT07579.1 - 0.13 13.0 13.3 0.46 11.2 0.3 3.5 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) AKNA PF12443.8 KXT07579.1 - 0.17 12.6 9.9 0.3 11.8 0.2 3.0 2 0 0 2 2 2 0 AT-hook-containing transcription factor ADIP PF11559.8 KXT07579.1 - 0.48 10.5 18.5 0.47 10.5 0.2 3.5 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding DUF5320 PF17253.2 KXT07579.1 - 0.72 11.0 3.3 6.6 7.9 0.2 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5320) DUF1664 PF07889.12 KXT07579.1 - 1.4 8.9 5.9 6.9 6.7 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF4337 PF14235.6 KXT07579.1 - 1.5 8.9 12.1 3.6 7.7 2.3 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4337) MnmE_helical PF12631.7 KXT07579.1 - 1.9 8.6 11.2 23 5.1 11.3 2.2 1 1 0 1 1 1 0 MnmE helical domain Noelin-1 PF12308.8 KXT07579.1 - 2.1 8.4 5.3 1 9.3 0.1 3.0 3 0 0 3 3 3 0 Neurogenesis glycoprotein DUF4611 PF15387.6 KXT07579.1 - 2.6 8.3 25.4 2.2 8.6 3.1 4.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4611) YabA PF06156.13 KXT07579.1 - 3.7 8.2 9.0 31 5.3 0.5 3.4 3 0 0 3 3 3 0 Initiation control protein YabA HIT PF01230.23 KXT07580.1 - 8.4e-24 84.2 0.3 1.5e-23 83.4 0.3 1.4 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KXT07580.1 - 3.3e-05 24.3 0.1 5.4e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KXT07580.1 - 8.3e-05 22.5 0.0 0.00012 21.9 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 FtsK_SpoIIIE PF01580.18 KXT07582.1 - 0.06 12.7 0.1 0.36 10.1 0.1 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family EF-hand_7 PF13499.6 KXT07584.1 - 3.3e-11 43.5 1.6 1.2e-07 32.0 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 KXT07584.1 - 1.2e-09 38.3 0.1 7.5e-05 23.0 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KXT07584.1 - 1.7e-08 33.4 1.5 0.025 14.1 0.0 3.6 3 1 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KXT07584.1 - 1.7e-08 33.7 2.3 0.0044 16.8 0.1 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 KXT07584.1 - 2.6e-07 30.4 1.9 3.4e-05 23.6 0.4 3.1 2 1 1 3 3 3 1 EF-hand domain pair DED PF01335.21 KXT07584.1 - 0.13 12.6 0.2 5.6 7.3 0.0 2.2 2 0 0 2 2 2 0 Death effector domain GPHH PF16905.5 KXT07584.1 - 0.16 11.8 0.0 2.7 7.8 0.0 2.4 3 0 0 3 3 3 0 Voltage-dependent L-type calcium channel, IQ-associated EF-hand_1 PF00036.32 KXT07585.1 - 1.8e-24 83.4 8.0 1.6e-07 30.3 0.1 4.9 4 1 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 KXT07585.1 - 7.9e-22 75.3 3.8 0.00011 21.8 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 KXT07585.1 - 8.7e-19 67.1 4.2 8e-11 41.6 0.1 3.8 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 KXT07585.1 - 1.4e-18 65.5 6.7 0.00076 18.9 0.2 4.6 4 1 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KXT07585.1 - 4e-18 65.6 7.3 9.6e-10 38.8 0.1 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_4 PF12763.7 KXT07585.1 - 0.067 13.1 1.0 2.5 8.1 0.0 2.6 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand Abhydrolase_6 PF12697.7 KXT07586.1 - 2.4e-12 47.9 0.0 3.8e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KXT07586.1 - 1.6e-10 41.1 0.0 1e-05 25.3 0.0 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KXT07586.1 - 6.8e-06 25.5 0.0 1.1e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 7tm_3 PF00003.22 KXT07592.1 - 1.9e-05 24.5 11.7 3.3e-05 23.7 11.7 1.4 1 1 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR DUF420 PF04238.12 KXT07592.1 - 0.0074 16.6 2.1 0.023 15.0 2.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF420) ABC_membrane_3 PF13748.6 KXT07592.1 - 0.036 13.3 1.1 0.07 12.3 1.1 1.4 1 0 0 1 1 1 0 ABC transporter transmembrane region Helicase_C PF00271.31 KXT07593.1 - 3.3e-20 72.5 0.1 1.4e-19 70.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXT07593.1 - 1.8e-18 67.2 0.0 4.7e-18 65.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KXT07593.1 - 2.9e-15 56.5 0.0 5.5e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Peptidase_M1_N PF17900.1 KXT07594.1 - 1.4e-08 35.1 0.2 0.0079 16.4 0.0 2.5 2 0 0 2 2 2 2 Peptidase M1 N-terminal domain HEAT_2 PF13646.6 KXT07594.1 - 0.0051 17.2 0.2 0.049 14.0 0.0 2.8 3 0 0 3 3 3 1 HEAT repeats FlxA PF14282.6 KXT07594.1 - 6.4 6.8 9.9 1.3 9.1 5.0 2.3 2 0 0 2 2 2 0 FlxA-like protein FAD_binding_4 PF01565.23 KXT07597.1 - 7.4e-19 67.9 0.2 2.2e-18 66.3 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KXT07597.1 - 1.6e-06 28.1 0.0 3.9e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like Acyl_transf_3 PF01757.22 KXT07598.1 - 6.5e-29 101.1 39.3 3.7e-28 98.6 39.3 2.1 1 1 0 1 1 1 1 Acyltransferase family CtIP_N PF10482.9 KXT07599.1 - 0.073 13.1 1.6 0.85 9.7 0.1 2.3 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain Zn_Tnp_IS1595 PF12760.7 KXT07600.1 - 0.033 14.2 0.5 0.084 12.9 0.5 1.7 1 0 0 1 1 1 0 Transposase zinc-ribbon domain DZR PF12773.7 KXT07600.1 - 0.035 14.1 0.8 0.077 13.0 0.8 1.5 1 0 0 1 1 1 0 Double zinc ribbon RE_Alw26IDE PF09665.10 KXT07600.1 - 0.24 10.5 0.0 7.4 5.6 0.0 2.0 2 0 0 2 2 2 0 Type II restriction endonuclease (RE_Alw26IDE) zf-NADH-PPase PF09297.11 KXT07600.1 - 1.2 8.8 6.0 2.8 7.7 6.0 1.6 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain TFIIS_M PF07500.14 KXT07601.1 - 1.3e-27 96.5 2.4 1.3e-27 96.5 2.4 1.8 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain Med26 PF08711.11 KXT07601.1 - 1.4e-12 47.4 0.2 3.2e-12 46.3 0.2 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain CLIP_1 PF18322.1 KXT07602.1 - 0.13 12.4 0.3 0.19 11.8 0.3 1.3 1 0 0 1 1 1 0 Serine protease Clip domain PPAF-2 Kinesin PF00225.23 KXT07604.1 - 3.1e-56 190.7 0.0 5.1e-56 190.0 0.0 1.3 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KXT07604.1 - 3.3e-12 46.6 0.0 6.1e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding AAA_16 PF13191.6 KXT07604.1 - 0.021 15.2 0.1 0.04 14.3 0.1 1.5 1 0 0 1 1 1 0 AAA ATPase domain DUF87 PF01935.17 KXT07604.1 - 0.026 14.6 0.0 0.05 13.7 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain G-alpha PF00503.20 KXT07604.1 - 0.087 12.0 0.0 0.098 11.8 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit Ribosomal_S3_C PF00189.20 KXT07605.1 - 0.028 14.9 0.8 0.11 13.1 0.8 2.0 1 1 0 1 1 1 0 Ribosomal protein S3, C-terminal domain DUF202 PF02656.15 KXT07606.1 - 6.8e-15 55.3 0.1 6.8e-15 55.3 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Trypan_PARP PF05887.11 KXT07606.1 - 0.21 11.5 2.5 0.33 10.9 2.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF973 PF06157.11 KXT07607.1 - 0.018 14.1 0.4 0.018 14.1 0.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF973) DUF3611 PF12263.8 KXT07607.1 - 1.7 8.5 10.4 0.17 11.7 4.8 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3611) Piwi PF02171.17 KXT07608.1 - 5.3e-32 111.3 0.0 4e-24 85.4 0.0 2.1 2 0 0 2 2 2 2 Piwi domain Barwin PF00967.17 KXT07609.1 - 6.6e-05 22.7 0.6 0.00014 21.7 0.6 1.5 1 0 0 1 1 1 1 Barwin family DPBB_1 PF03330.18 KXT07609.1 - 0.0064 16.7 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 Lytic transglycolase DUF2845 PF11006.8 KXT07609.1 - 0.25 11.5 1.8 0.48 10.6 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2845) Senescence_reg PF04520.13 KXT07609.1 - 2.5 8.9 7.5 4.8 8.0 7.5 1.5 1 1 0 1 1 1 0 Senescence regulator IgaA PF07095.11 KXT07614.1 - 0.08 10.9 0.7 0.096 10.7 0.7 1.0 1 0 0 1 1 1 0 Intracellular growth attenuator protein IgaA Usp PF00582.26 KXT07615.1 - 0.11 13.1 0.1 0.19 12.2 0.1 1.4 1 0 0 1 1 1 0 Universal stress protein family CD24 PF14984.6 KXT07615.1 - 0.25 11.6 1.9 5.5 7.3 2.2 2.2 2 0 0 2 2 2 0 CD24 protein WD40 PF00400.32 KXT07617.1 - 2.3e-13 50.4 6.8 0.0019 19.0 0.1 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat RTC4 PF14474.6 KXT07618.1 - 2.9e-24 85.5 1.1 1e-23 83.8 0.0 2.4 2 1 0 2 2 2 1 RTC4-like domain RTC4 PF14474.6 KXT07619.1 - 3e-24 85.5 1.1 1e-23 83.8 0.0 2.4 2 1 0 2 2 2 1 RTC4-like domain Amidase PF01425.21 KXT07621.1 - 1.4e-10 40.7 0.0 1.6e-10 40.5 0.0 1.0 1 0 0 1 1 1 1 Amidase 7tm_2 PF00002.24 KXT07624.1 - 0.00023 20.5 7.4 0.00023 20.5 7.4 2.1 2 0 0 2 2 2 2 7 transmembrane receptor (Secretin family) RNase_P_p30 PF01876.16 KXT07625.1 - 4.6e-55 186.4 0.0 6.4e-55 185.9 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit p30 Glyco_hydro_16 PF00722.21 KXT07626.1 - 5.5e-06 26.0 0.1 2.1e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Aldolase_II PF00596.21 KXT07627.1 - 5.2e-49 166.7 0.0 7e-49 166.3 0.0 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DHHC PF01529.20 KXT07628.1 - 5.4e-28 97.8 7.7 5.4e-28 97.8 7.7 1.8 2 1 0 2 2 2 1 DHHC palmitoyltransferase DHHC PF01529.20 KXT07629.1 - 3e-20 72.7 20.3 3e-20 72.7 20.3 2.7 2 2 0 2 2 2 1 DHHC palmitoyltransferase tRNA-synt_2c PF01411.19 KXT07630.1 - 4.7e-217 721.9 0.2 4.7e-217 721.9 0.2 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KXT07630.1 - 2.6e-17 62.6 0.2 5.9e-17 61.5 0.2 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 KXT07630.1 - 8.9e-10 39.1 5.9 2e-09 38.0 5.9 1.6 1 0 0 1 1 1 1 DHHA1 domain BAH PF01426.18 KXT07631.1 - 8.1e-09 35.4 0.1 1.9e-08 34.2 0.0 1.6 2 0 0 2 2 2 1 BAH domain zf-HC5HC2H PF13771.6 KXT07631.1 - 0.0029 17.8 0.5 0.0069 16.6 0.5 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KXT07631.1 - 0.0088 16.2 0.3 0.018 15.2 0.3 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain PHD PF00628.29 KXT07631.1 - 0.025 14.5 1.1 0.025 14.5 1.1 2.0 2 0 0 2 2 2 0 PHD-finger zf-RING-like PF08746.11 KXT07631.1 - 0.077 13.3 0.6 0.51 10.7 0.4 2.1 2 0 0 2 2 2 0 RING-like domain FANCL_C PF11793.8 KXT07631.1 - 0.27 11.5 1.8 0.38 10.9 1.0 1.6 2 0 0 2 2 2 0 FANCL C-terminal domain Epimerase PF01370.21 KXT07632.1 - 5.4e-21 75.2 0.0 8.2e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KXT07632.1 - 2.6e-06 27.1 0.0 1.1e-05 25.1 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KXT07632.1 - 2.7e-06 26.7 0.0 4.5e-06 26.0 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KXT07632.1 - 0.00029 19.9 0.0 0.0018 17.3 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 KXT07632.1 - 0.011 16.0 0.1 0.062 13.6 0.0 2.2 2 1 1 3 3 3 0 Saccharopine dehydrogenase NADP binding domain Ldh_1_N PF00056.23 KXT07632.1 - 0.094 12.8 0.0 0.31 11.1 0.0 1.8 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Cmc1 PF08583.10 KXT07634.1 - 6.4e-17 61.3 6.2 7.3e-17 61.1 6.2 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 KXT07634.1 - 0.24 11.5 3.5 5.5 7.1 0.4 2.2 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DUF3128 PF11326.8 KXT07634.1 - 0.38 11.1 5.8 1.2 9.5 5.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) PH_9 PF15410.6 KXT07635.1 - 0.0019 18.6 0.8 0.0079 16.6 0.0 2.4 3 0 0 3 3 3 1 Pleckstrin homology domain PH PF00169.29 KXT07635.1 - 0.0066 16.9 0.0 0.03 14.8 0.0 2.1 2 0 0 2 2 2 1 PH domain TEX12 PF15219.6 KXT07635.1 - 0.14 12.5 0.1 0.31 11.4 0.1 1.4 1 0 0 1 1 1 0 Testis-expressed 12 LSM PF01423.22 KXT07636.1 - 2.5e-20 71.9 0.4 3.2e-20 71.6 0.4 1.1 1 0 0 1 1 1 1 LSM domain Nop14 PF04147.12 KXT07637.1 - 2.6e-230 767.1 29.9 5.5e-182 607.2 10.5 2.4 1 1 1 2 2 2 2 Nop14-like family PBC PF03792.13 KXT07637.1 - 0.00037 20.3 0.2 0.0014 18.5 0.2 2.0 1 0 0 1 1 1 1 PBC domain MFS_1 PF07690.16 KXT07638.1 - 4.9e-08 32.3 47.5 1.2e-05 24.5 10.7 3.1 1 1 2 3 3 3 2 Major Facilitator Superfamily UNC-93 PF05978.16 KXT07638.1 - 0.00025 20.8 4.8 0.00025 20.8 4.8 2.2 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 DUF1772 PF08592.11 KXT07638.1 - 7.7 6.8 8.5 6.2 7.1 2.8 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF1772) FAD_binding_2 PF00890.24 KXT07639.1 - 7e-82 275.7 0.1 9.7e-82 275.3 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 KXT07639.1 - 1.7e-19 69.7 0.5 1.2e-18 67.0 0.1 2.7 4 0 0 4 4 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 KXT07639.1 - 1.8e-11 44.3 0.6 9.4e-11 41.9 0.4 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KXT07639.1 - 6.3e-10 39.0 0.4 3.1e-09 36.7 0.4 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KXT07639.1 - 5e-09 36.3 0.3 1.1e-07 32.0 0.1 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KXT07639.1 - 3.1e-07 29.9 0.0 1e-06 28.2 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KXT07639.1 - 3.9e-07 29.1 0.9 0.0015 17.3 0.1 3.1 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_3 PF13738.6 KXT07639.1 - 4.3e-07 29.5 0.1 0.029 13.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KXT07639.1 - 8.9e-05 21.7 0.7 0.019 14.1 0.3 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 KXT07639.1 - 0.00023 20.5 0.5 0.024 13.9 0.1 2.5 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 KXT07639.1 - 0.0054 16.0 0.0 0.0085 15.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 KXT07639.1 - 0.027 13.8 0.2 2 7.6 0.0 2.8 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 KXT07639.1 - 0.052 12.8 0.1 0.097 12.0 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KXT07639.1 - 0.16 12.5 1.3 12 6.6 0.1 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ank_2 PF12796.7 KXT07640.1 - 4.5e-20 72.0 0.0 1.1e-07 32.4 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KXT07640.1 - 1e-15 56.2 0.0 3.2e-05 24.0 0.0 5.6 4 1 1 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 KXT07640.1 - 4.7e-15 55.4 0.2 9.3e-09 35.4 0.0 4.6 2 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 KXT07640.1 - 1.7e-14 53.5 0.0 1.3e-05 25.4 0.0 4.7 4 1 1 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 KXT07640.1 - 2.3e-11 44.0 0.0 0.002 18.7 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeats (many copies) YqjK PF13997.6 KXT07640.1 - 0.0023 18.1 1.8 0.0037 17.5 0.5 2.1 2 0 0 2 2 2 1 YqjK-like protein XET_C PF06955.12 KXT07640.1 - 0.0082 16.0 0.5 1.4 8.8 0.2 2.5 2 0 0 2 2 2 2 Xyloglucan endo-transglycosylase (XET) C-terminus F-box-like PF12937.7 KXT07641.1 - 1.5e-05 24.7 0.0 3.2e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KXT07641.1 - 0.00066 19.5 0.4 0.0013 18.6 0.0 1.7 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 KXT07641.1 - 0.16 11.8 0.0 0.79 9.6 0.0 2.0 2 0 0 2 2 2 0 F-box MFS_1 PF07690.16 KXT07642.1 - 2.8e-15 56.1 58.4 1.2e-10 40.8 35.6 2.7 1 1 2 3 3 3 3 Major Facilitator Superfamily EPV_E5 PF08135.11 KXT07642.1 - 0.2 12.1 0.2 0.2 12.1 0.2 3.9 3 0 0 3 3 3 0 Major transforming protein E5 family Efg1 PF10153.9 KXT07643.1 - 0.025 14.9 6.0 0.044 14.2 6.0 1.3 1 0 0 1 1 1 0 rRNA-processing protein Efg1 zf-H2C2_5 PF13909.6 KXT07643.1 - 0.14 11.9 0.4 0.27 11.0 0.4 1.5 1 0 0 1 1 1 0 C2H2-type zinc-finger domain SAP PF02037.27 KXT07645.1 - 0.0027 17.4 0.0 0.0085 15.8 0.0 1.9 1 0 0 1 1 1 1 SAP domain PCNA_C PF02747.15 KXT07646.1 - 4e-52 175.8 0.0 1.4e-50 170.8 0.0 2.1 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.18 KXT07646.1 - 4.5e-49 165.4 2.4 6.7e-49 164.8 1.7 1.6 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain Rad9 PF04139.13 KXT07646.1 - 3.6e-09 36.5 0.1 4.3e-09 36.2 0.1 1.1 1 0 0 1 1 1 1 Rad9 AMA-1 PF02430.15 KXT07646.1 - 0.049 12.6 0.0 0.066 12.2 0.0 1.2 1 0 0 1 1 1 0 Apical membrane antigen 1 Calreticulin PF00262.18 KXT07647.1 - 2.3e-167 556.5 15.8 2.3e-167 556.5 15.8 1.7 2 0 0 2 2 2 1 Calreticulin family CWC25 PF12542.8 KXT07647.1 - 1.5 9.8 6.3 0.52 11.2 0.2 2.6 2 0 0 2 2 2 0 Pre-mRNA splicing factor Phos_pyr_kin PF08543.12 KXT07648.1 - 5.2e-12 45.7 0.0 1.1e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 KXT07648.1 - 4.7e-06 26.1 0.0 0.00029 20.2 0.0 2.2 2 0 0 2 2 2 2 pfkB family carbohydrate kinase PCNA_C PF02747.15 KXT07649.1 - 4e-52 175.8 0.0 1.4e-50 170.8 0.0 2.1 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.18 KXT07649.1 - 4.5e-49 165.4 2.4 6.7e-49 164.8 1.7 1.6 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain Rad9 PF04139.13 KXT07649.1 - 3.6e-09 36.5 0.1 4.3e-09 36.2 0.1 1.1 1 0 0 1 1 1 1 Rad9 AMA-1 PF02430.15 KXT07649.1 - 0.049 12.6 0.0 0.066 12.2 0.0 1.2 1 0 0 1 1 1 0 Apical membrane antigen 1 Phos_pyr_kin PF08543.12 KXT07650.1 - 5.2e-12 45.7 0.0 1e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 KXT07650.1 - 4.6e-06 26.2 0.0 0.00031 20.2 0.0 2.2 2 0 0 2 2 2 2 pfkB family carbohydrate kinase FMN_red PF03358.15 KXT07651.1 - 5.2e-09 36.0 0.0 7e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KXT07651.1 - 1.6e-06 28.0 0.0 2.1e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 KXT07651.1 - 5.8e-05 23.3 0.0 0.0013 18.9 0.0 2.3 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 KXT07651.1 - 0.046 13.9 0.0 0.54 10.5 0.0 2.0 1 1 1 2 2 2 0 Flavodoxin domain DUF1708 PF08101.11 KXT07652.1 - 1e-159 532.3 0.0 1.6e-159 531.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) Methyltransf_25 PF13649.6 KXT07652.1 - 1.1e-15 58.1 0.0 7.2e-15 55.5 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KXT07652.1 - 3e-12 47.1 0.0 1.6e-11 44.8 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KXT07652.1 - 7.7e-12 45.3 0.0 3.9e-11 43.0 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 KXT07652.1 - 1.4e-11 44.9 0.0 7.1e-11 42.6 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain PCMT PF01135.19 KXT07652.1 - 1.4e-05 25.0 0.0 2.6e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KXT07652.1 - 1.7e-05 24.4 0.0 3.6e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KXT07652.1 - 8.8e-05 21.9 0.0 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KXT07652.1 - 9.8e-05 21.9 0.0 0.00026 20.5 0.0 1.7 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.20 KXT07652.1 - 0.00026 20.4 0.0 0.00049 19.5 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KXT07652.1 - 0.00054 19.8 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KXT07652.1 - 0.0054 16.7 0.0 0.024 14.6 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 KXT07652.1 - 0.024 13.7 0.0 0.044 12.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PrmA PF06325.13 KXT07652.1 - 0.045 13.1 0.0 0.082 12.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 KXT07652.1 - 0.072 12.4 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase domain CDC73_C PF05179.14 KXT07653.1 - 8.3e-56 188.0 0.1 1.2e-55 187.5 0.1 1.3 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal Ribosomal_S21 PF01165.20 KXT07654.1 - 2e-11 43.4 6.1 3.5e-11 42.6 6.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S21 SelB-wing_2 PF09106.11 KXT07654.1 - 0.022 14.9 0.2 0.048 13.9 0.2 1.6 1 0 0 1 1 1 0 Elongation factor SelB, winged helix Pribosyltran PF00156.27 KXT07655.1 - 1.8e-17 63.3 0.1 2.7e-17 62.7 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KXT07655.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Methyltransf_16 PF10294.9 KXT07656.1 - 2.9e-09 36.9 0.1 8.9e-09 35.3 0.1 1.7 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_11 PF08241.12 KXT07656.1 - 0.11 13.1 0.0 0.24 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain CoA_binding_2 PF13380.6 KXT07657.1 - 4e-10 40.2 0.1 5.3e-08 33.3 0.0 2.2 1 1 1 2 2 2 2 CoA binding domain GxGYxYP_C PF14323.6 KXT07658.1 - 6.9e-54 183.3 1.0 1.1e-53 182.7 0.0 1.8 3 0 0 3 3 3 1 GxGYxYP putative glycoside hydrolase C-terminal domain GxGYxYP_N PF16216.5 KXT07658.1 - 5e-44 151.1 2.2 7.6e-26 91.6 0.4 2.3 2 0 0 2 2 2 2 GxGYxY sequence motif in domain of unknown function N-terminal Pkinase PF00069.25 KXT07660.1 - 5.4e-12 45.6 0.0 1.6e-09 37.5 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KXT07660.1 - 5.8e-09 35.6 0.0 3.2e-07 29.9 0.0 2.8 1 1 0 1 1 1 1 Protein tyrosine kinase dUTPase PF00692.19 KXT07661.1 - 1.3e-42 144.5 0.0 1.7e-42 144.1 0.0 1.1 1 0 0 1 1 1 1 dUTPase RRM_1 PF00076.22 KXT07663.1 - 0.048 13.5 0.0 0.19 11.5 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zn-ribbon_8 PF09723.10 KXT07663.1 - 2.2 8.5 9.8 0.16 12.1 1.7 2.5 2 0 0 2 2 2 0 Zinc ribbon domain HET PF06985.11 KXT07664.1 - 2.1e-27 96.3 1.3 2.6e-26 92.7 0.0 2.8 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) APH PF01636.23 KXT07668.1 - 3.7e-38 131.8 0.0 1.1e-37 130.2 0.0 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 KXT07668.1 - 0.0014 18.0 0.0 0.0027 17.1 0.0 1.5 1 1 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.22 KXT07668.1 - 0.0021 17.7 0.0 0.036 13.7 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 KXT07668.1 - 0.097 12.0 0.0 0.24 10.7 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family GFA PF04828.14 KXT07669.1 - 8.9e-14 51.6 0.0 1.3e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme RRF PF01765.19 KXT07670.1 - 2.2e-40 138.3 3.5 2.9e-40 137.9 3.5 1.1 1 0 0 1 1 1 1 Ribosome recycling factor RapA_C PF12137.8 KXT07670.1 - 0.083 11.9 0.3 0.14 11.1 0.3 1.3 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal BTB PF00651.31 KXT07671.1 - 0.0016 18.6 0.0 0.002 18.3 0.0 1.4 1 1 0 1 1 1 1 BTB/POZ domain U-box PF04564.15 KXT07673.1 - 4.7e-19 68.3 0.0 1.1e-18 67.2 0.0 1.6 1 0 0 1 1 1 1 U-box domain TPR_1 PF00515.28 KXT07673.1 - 8.4e-11 41.2 5.5 0.00084 19.1 0.9 4.4 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KXT07673.1 - 2.3e-10 39.8 4.9 0.00027 20.8 0.8 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 KXT07673.1 - 3e-07 30.8 1.9 4.6e-05 23.8 0.2 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KXT07673.1 - 3.4e-07 30.5 8.9 0.0022 18.3 0.4 3.6 3 1 1 4 4 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KXT07673.1 - 6.1e-06 26.4 2.4 0.013 15.7 0.2 2.5 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KXT07673.1 - 6.7e-06 25.8 1.4 0.021 14.8 0.2 3.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KXT07673.1 - 6.9e-06 26.6 5.0 1.7e-05 25.4 0.2 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat CHIP_TPR_N PF18391.1 KXT07673.1 - 8.3e-05 23.3 6.6 0.00017 22.3 6.6 1.5 1 0 0 1 1 1 1 CHIP N-terminal tetratricopeptide repeat domain TPR_10 PF13374.6 KXT07673.1 - 0.00011 21.9 2.7 0.027 14.3 0.2 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat zf-Nse PF11789.8 KXT07673.1 - 0.00028 20.7 0.2 0.00081 19.2 0.2 1.7 1 1 1 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 KXT07673.1 - 0.0063 16.6 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein TPR_8 PF13181.6 KXT07673.1 - 0.0071 16.5 2.5 1.3 9.4 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 KXT07673.1 - 0.045 14.2 4.0 3.2 8.3 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.9 KXT07673.1 - 0.051 13.3 0.5 0.051 13.3 0.5 2.2 2 1 0 2 2 2 0 Tetratricopeptide repeat-like domain TPR_14 PF13428.6 KXT07673.1 - 0.086 13.7 7.9 0.31 12.0 0.1 3.9 3 1 2 5 5 4 0 Tetratricopeptide repeat DUF2777 PF10949.8 KXT07673.1 - 0.093 12.4 1.5 0.2 11.3 0.2 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2777) TPR_6 PF13174.6 KXT07673.1 - 0.25 12.0 5.8 1.5 9.6 0.5 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 KXT07673.1 - 0.34 10.6 6.2 0.18 11.5 0.7 3.0 2 1 1 3 3 3 0 TPR repeat CAP_GLY PF01302.25 KXT07674.1 - 1.2e-16 60.5 0.6 2.4e-16 59.5 0.6 1.5 1 0 0 1 1 1 1 CAP-Gly domain CLIP1_ZNF PF16641.5 KXT07674.1 - 6.2e-07 29.1 12.8 0.0013 18.6 4.9 2.7 2 0 0 2 2 2 2 CLIP1 zinc knuckle ATG16 PF08614.11 KXT07674.1 - 0.0013 19.0 10.6 0.0013 19.0 10.6 3.6 1 1 2 3 3 3 1 Autophagy protein 16 (ATG16) DUF3583 PF12126.8 KXT07674.1 - 0.0061 16.1 4.2 0.0061 16.1 4.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3583) BLOC1_2 PF10046.9 KXT07674.1 - 0.0079 16.5 5.5 0.093 13.0 2.9 3.0 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 KXT07674.1 - 0.05 14.1 2.8 1.2 9.7 0.3 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein SesA PF17107.5 KXT07674.1 - 0.058 13.6 1.9 0.076 13.2 0.0 2.2 3 0 0 3 3 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases zf-CCHC_3 PF13917.6 KXT07674.1 - 0.14 12.1 6.2 0.085 12.8 1.2 2.7 2 0 0 2 2 2 0 Zinc knuckle Sec8_exocyst PF04048.14 KXT07674.1 - 0.19 11.6 10.4 0.3 11.0 2.6 3.5 3 1 1 4 4 4 0 Sec8 exocyst complex component specific domain Prominin PF05478.11 KXT07674.1 - 0.23 9.3 0.5 0.33 8.8 0.5 1.2 1 0 0 1 1 1 0 Prominin AKNA PF12443.8 KXT07674.1 - 0.25 12.0 4.5 0.51 11.0 1.1 3.3 2 0 0 2 2 2 0 AT-hook-containing transcription factor T2SSF PF00482.23 KXT07674.1 - 0.36 10.8 8.8 3.1 7.8 0.5 2.9 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F DUF241 PF03087.14 KXT07674.1 - 0.45 10.3 8.7 0.25 11.2 5.4 2.1 2 1 0 2 2 2 0 Arabidopsis protein of unknown function TPR_MLP1_2 PF07926.12 KXT07674.1 - 0.59 10.2 30.1 4 7.5 12.1 4.2 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein FH2 PF02181.23 KXT07674.1 - 0.73 8.9 6.4 2.3 7.2 1.8 2.2 1 1 1 2 2 2 0 Formin Homology 2 Domain DUF745 PF05335.13 KXT07674.1 - 0.89 9.3 16.8 1.7 8.4 1.4 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF745) Wtap PF17098.5 KXT07674.1 - 1.1 9.2 17.6 1 9.3 12.3 2.4 2 0 0 2 2 2 0 WTAP/Mum2p family Med4 PF10018.9 KXT07674.1 - 1.5 8.5 9.7 3.9 7.1 1.2 3.1 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF16 PF01519.16 KXT07674.1 - 1.8 9.1 6.9 14 6.3 0.1 2.8 1 1 1 2 2 2 0 Protein of unknown function DUF16 DASH_Dad2 PF08654.10 KXT07674.1 - 2.7 8.5 7.3 0.23 11.9 0.9 2.6 3 0 0 3 3 1 0 DASH complex subunit Dad2 DUF2203 PF09969.9 KXT07674.1 - 2.9 8.7 17.4 26 5.5 1.9 4.2 3 1 1 4 4 4 0 Uncharacterized conserved protein (DUF2203) AAA_13 PF13166.6 KXT07674.1 - 3.4 6.2 9.9 0.16 10.6 4.2 1.6 2 0 0 2 2 2 0 AAA domain Fez1 PF06818.15 KXT07674.1 - 3.4 8.1 31.2 0.17 12.3 14.0 3.2 1 1 0 3 3 3 0 Fez1 HIP1_clath_bdg PF16515.5 KXT07674.1 - 4.1 8.1 29.0 16 6.2 0.6 5.0 2 1 3 5 5 5 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1664 PF07889.12 KXT07674.1 - 6.5 6.8 7.1 1 9.4 0.7 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Tup_N PF08581.10 KXT07674.1 - 6.6 7.1 18.8 4.7 7.6 0.5 4.7 4 1 0 4 4 4 0 Tup N-terminal Spc7 PF08317.11 KXT07674.1 - 8.5 5.2 29.3 1.7 7.5 12.1 3.6 2 1 1 4 4 4 0 Spc7 kinetochore protein CAP_GLY PF01302.25 KXT07675.1 - 1.2e-16 60.5 0.6 2.4e-16 59.5 0.6 1.5 1 0 0 1 1 1 1 CAP-Gly domain CLIP1_ZNF PF16641.5 KXT07675.1 - 6.2e-07 29.1 12.8 0.0013 18.6 4.9 2.7 2 0 0 2 2 2 2 CLIP1 zinc knuckle ATG16 PF08614.11 KXT07675.1 - 0.0013 19.0 10.6 0.0013 19.0 10.6 3.6 1 1 2 3 3 3 1 Autophagy protein 16 (ATG16) DUF3583 PF12126.8 KXT07675.1 - 0.0061 16.1 4.2 0.0061 16.1 4.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3583) BLOC1_2 PF10046.9 KXT07675.1 - 0.0079 16.5 5.5 0.093 13.0 2.9 3.0 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 KXT07675.1 - 0.05 14.1 2.8 1.2 9.7 0.3 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein SesA PF17107.5 KXT07675.1 - 0.058 13.6 1.9 0.076 13.2 0.0 2.2 3 0 0 3 3 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases zf-CCHC_3 PF13917.6 KXT07675.1 - 0.14 12.1 6.2 0.085 12.8 1.2 2.7 2 0 0 2 2 2 0 Zinc knuckle Sec8_exocyst PF04048.14 KXT07675.1 - 0.19 11.6 10.4 0.3 11.0 2.6 3.5 3 1 1 4 4 4 0 Sec8 exocyst complex component specific domain Prominin PF05478.11 KXT07675.1 - 0.23 9.3 0.5 0.33 8.8 0.5 1.2 1 0 0 1 1 1 0 Prominin AKNA PF12443.8 KXT07675.1 - 0.25 12.0 4.5 0.51 11.0 1.1 3.3 2 0 0 2 2 2 0 AT-hook-containing transcription factor T2SSF PF00482.23 KXT07675.1 - 0.36 10.8 8.8 3.1 7.8 0.5 2.9 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F DUF241 PF03087.14 KXT07675.1 - 0.45 10.3 8.7 0.25 11.2 5.4 2.1 2 1 0 2 2 2 0 Arabidopsis protein of unknown function TPR_MLP1_2 PF07926.12 KXT07675.1 - 0.59 10.2 30.1 4 7.5 12.1 4.2 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein FH2 PF02181.23 KXT07675.1 - 0.73 8.9 6.4 2.3 7.2 1.8 2.2 1 1 1 2 2 2 0 Formin Homology 2 Domain DUF745 PF05335.13 KXT07675.1 - 0.89 9.3 16.8 1.7 8.4 1.4 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF745) Wtap PF17098.5 KXT07675.1 - 1.1 9.2 17.6 1 9.3 12.3 2.4 2 0 0 2 2 2 0 WTAP/Mum2p family Med4 PF10018.9 KXT07675.1 - 1.5 8.5 9.7 3.9 7.1 1.2 3.1 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF16 PF01519.16 KXT07675.1 - 1.8 9.1 6.9 14 6.3 0.1 2.8 1 1 1 2 2 2 0 Protein of unknown function DUF16 DASH_Dad2 PF08654.10 KXT07675.1 - 2.7 8.5 7.3 0.23 11.9 0.9 2.6 3 0 0 3 3 1 0 DASH complex subunit Dad2 DUF2203 PF09969.9 KXT07675.1 - 2.9 8.7 17.4 26 5.5 1.9 4.2 3 1 1 4 4 4 0 Uncharacterized conserved protein (DUF2203) AAA_13 PF13166.6 KXT07675.1 - 3.4 6.2 9.9 0.16 10.6 4.2 1.6 2 0 0 2 2 2 0 AAA domain Fez1 PF06818.15 KXT07675.1 - 3.4 8.1 31.2 0.17 12.3 14.0 3.2 1 1 0 3 3 3 0 Fez1 HIP1_clath_bdg PF16515.5 KXT07675.1 - 4.1 8.1 29.0 16 6.2 0.6 5.0 2 1 3 5 5 5 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1664 PF07889.12 KXT07675.1 - 6.5 6.8 7.1 1 9.4 0.7 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Tup_N PF08581.10 KXT07675.1 - 6.6 7.1 18.8 4.7 7.6 0.5 4.7 4 1 0 4 4 4 0 Tup N-terminal Spc7 PF08317.11 KXT07675.1 - 8.5 5.2 29.3 1.7 7.5 12.1 3.6 2 1 1 4 4 4 0 Spc7 kinetochore protein OST3_OST6 PF04756.13 KXT07676.1 - 0.27 10.6 0.0 0.27 10.6 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family DUF2418 PF10332.9 KXT07677.1 - 2.5e-33 114.5 1.6 2.9e-33 114.2 0.1 1.9 3 0 0 3 3 3 1 Protein of unknown function (DUF2418) adh_short PF00106.25 KXT07678.1 - 3.8e-35 121.1 0.0 5.2e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT07678.1 - 1.1e-32 113.5 0.1 1.6e-32 113.0 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT07678.1 - 9.5e-08 32.1 0.1 1.7e-06 28.1 0.1 2.3 2 1 0 2 2 2 1 KR domain Epimerase PF01370.21 KXT07678.1 - 0.031 13.7 0.2 0.058 12.8 0.1 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family AlaDh_PNT_C PF01262.21 KXT07678.1 - 0.092 12.0 0.1 0.14 11.4 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 KXT07680.1 - 3.3e-35 121.3 0.0 4.4e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KXT07680.1 - 9.5e-33 113.7 0.1 1.3e-32 113.2 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KXT07680.1 - 8.1e-08 32.4 0.1 1.5e-06 28.2 0.1 2.3 2 1 0 2 2 2 1 KR domain Epimerase PF01370.21 KXT07680.1 - 0.027 14.0 0.2 0.053 13.0 0.1 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family AlaDh_PNT_C PF01262.21 KXT07680.1 - 0.084 12.2 0.1 0.13 11.5 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain CFEM PF05730.11 KXT07682.1 - 1.8e-26 92.0 60.7 2.3e-09 37.2 13.1 4.7 4 0 0 4 4 4 3 CFEM domain Glyco_hydro_16 PF00722.21 KXT07682.1 - 4.3e-05 23.0 0.0 0.00016 21.2 0.0 2.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 ADH_N PF08240.12 KXT07683.1 - 3.1e-27 94.6 4.4 6e-27 93.7 4.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KXT07683.1 - 7.2e-19 68.1 0.1 1.2e-18 67.4 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KXT07683.1 - 3.6e-05 23.3 0.8 0.00012 21.7 0.8 1.8 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KXT07683.1 - 6.5e-05 24.0 0.0 0.0001 23.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KXT07683.1 - 0.0028 17.0 0.1 0.0058 16.0 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 KXT07683.1 - 0.064 12.5 0.1 0.12 11.6 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KXT07683.1 - 0.47 9.7 1.7 0.73 9.0 1.7 1.2 1 0 0 1 1 1 0 FAD binding domain ORC_WH_C PF18137.1 KXT07684.1 - 2.4e-25 89.3 1.0 2.4e-17 63.3 0.1 4.3 3 2 1 4 4 4 2 Origin recognition complex winged helix C-terminal ORC3_N PF07034.11 KXT07684.1 - 1.3e-23 83.6 0.7 6.4e-22 78.1 0.7 2.5 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus DUF4187 PF13821.6 KXT07684.1 - 5.3e-11 42.1 1.6 1.7e-10 40.5 1.6 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 KXT07684.1 - 5e-09 35.9 3.0 1e-08 34.9 3.0 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KXT07684.1 - 0.26 11.4 7.4 0.18 11.9 1.8 2.6 2 0 0 2 2 2 0 G-patch domain DUF1998 PF09369.10 KXT07685.1 - 3.5e-20 72.5 1.4 6.9e-20 71.6 1.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) DEAD PF00270.29 KXT07686.1 - 2.3e-28 99.1 0.0 4.6e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KXT07686.1 - 1.2e-11 44.9 0.1 3.8e-11 43.3 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KXT07686.1 - 7.9e-07 29.2 0.0 1.4e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDT1 PF08839.11 KXT07686.1 - 4.9e-05 23.7 0.1 9.7e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 DNA replication factor CDT1 like PdaC PF13739.6 KXT07686.1 - 0.055 14.4 0.8 0.14 13.2 0.8 1.7 1 0 0 1 1 1 0 Deacetylase PdaC AMP-binding PF00501.28 KXT07689.1 - 1.6e-89 300.5 0.0 2.4e-89 299.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KXT07689.1 - 0.00016 22.6 0.1 0.0005 21.0 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain WD40 PF00400.32 KXT07690.1 - 8e-05 23.3 7.2 0.0013 19.5 0.8 5.0 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KXT07690.1 - 0.088 13.1 0.1 21 5.5 0.1 3.6 1 1 3 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain DUF3140 PF11338.8 KXT07691.1 - 2.2e-33 114.5 1.3 2.8e-33 114.2 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3140) SNase PF00565.17 KXT07692.1 - 3.3e-25 88.7 0.0 4.9e-25 88.1 0.0 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Tfb2_C PF18307.1 KXT07692.1 - 0.046 14.2 0.0 0.083 13.3 0.0 1.5 1 0 0 1 1 1 0 Transcription factor Tfb2 (p52) C-terminal domain Glyco_hydro_76 PF03663.14 KXT07692.1 - 0.14 11.6 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 76 Aldedh PF00171.22 KXT07695.1 - 1.2e-155 518.6 0.1 1.4e-155 518.4 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aldedh PF00171.22 KXT07696.1 - 1.2e-155 518.5 0.1 1.4e-155 518.3 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aldedh PF00171.22 KXT07697.1 - 1.7e-151 504.9 1.0 4.4e-86 289.2 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family PMR5N PF14416.6 KXT07697.1 - 0.082 13.2 0.7 0.43 10.9 0.1 2.2 2 0 0 2 2 2 0 PMR5 N terminal Domain Catalase PF00199.19 KXT07699.1 - 4.6e-152 506.6 0.0 5.9e-152 506.2 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KXT07699.1 - 1.4e-11 44.4 0.0 3e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive DUF4140 PF13600.6 KXT07700.1 - 0.17 12.3 0.4 6.9 7.2 0.0 2.1 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) PhoU_div PF01865.16 KXT07701.1 - 0.025 13.9 2.2 0.98 8.7 0.2 2.3 1 1 0 2 2 2 0 Protein of unknown function DUF47 SOGA PF11365.8 KXT07701.1 - 0.087 14.0 0.2 0.087 14.0 0.2 3.6 2 1 2 4 4 4 0 Protein SOGA DUF5082 PF16888.5 KXT07701.1 - 0.23 11.7 9.2 3 8.1 1.8 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) FAM76 PF16046.5 KXT07701.1 - 0.41 10.0 13.7 0.018 14.4 5.3 2.2 2 0 0 2 2 2 0 FAM76 protein DUF4094 PF13334.6 KXT07701.1 - 2.5 8.6 7.5 15 6.0 0.2 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4094) MutS_III PF05192.18 KXT07701.1 - 4.8 7.3 9.6 15 5.8 9.5 1.8 1 1 0 1 1 1 0 MutS domain III AAA PF00004.29 KXT07703.1 - 2.3e-12 47.5 0.0 3e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KXT07703.1 - 0.0023 18.2 0.1 0.019 15.2 0.1 1.9 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 KXT07703.1 - 0.015 14.7 0.0 0.028 13.8 0.0 1.5 2 0 0 2 2 2 0 Bacterial TniB protein T3SchapCesA PF11439.8 KXT07703.1 - 0.066 13.4 0.0 8.7 6.6 0.0 2.1 1 1 1 2 2 2 0 Type III secretion system filament chaperone CesA AAA_33 PF13671.6 KXT07703.1 - 0.16 12.1 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain MFS_1 PF07690.16 KXT07704.1 - 7.8e-22 77.7 26.7 7.8e-22 77.7 26.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KXT07704.1 - 0.00094 18.2 11.2 0.00094 18.2 11.2 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter 3-HAO PF06052.12 KXT07705.1 - 5.2e-58 195.0 0.0 7.9e-58 194.4 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase DZR PF12773.7 KXT07705.1 - 0.038 14.0 5.8 0.095 12.7 5.8 1.6 1 0 0 1 1 1 0 Double zinc ribbon Cupin_2 PF07883.11 KXT07705.1 - 0.088 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Cupin domain zinc_ribbon_2 PF13240.6 KXT07705.1 - 0.65 9.8 3.0 4.4 7.1 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.6 KXT07705.1 - 1.1 9.1 4.2 2.8 7.8 2.4 2.2 2 0 0 2 2 2 0 zinc-ribbon domain HEAT_2 PF13646.6 KXT07706.1 - 0.043 14.2 0.1 0.088 13.2 0.1 1.5 1 0 0 1 1 1 0 HEAT repeats DUF4440 PF14534.6 KXT07707.1 - 0.099 13.0 0.1 0.14 12.6 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4440) BTB PF00651.31 KXT07708.1 - 6.3e-18 65.0 0.2 1.8e-17 63.5 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain CBM_14 PF01607.24 KXT07708.1 - 0.00065 19.8 2.6 0.0011 19.1 0.5 2.2 2 0 0 2 2 2 1 Chitin binding Peritrophin-A domain # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Mycosphaerella_eumusae-ASM157823v1/GCA_001578235.1_ASM157823v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Mycosphaerella_eumusae-ASM157823v1/GCA_001578235.1_ASM157823v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Mycosphaerella_eumusae-ASM157823v1/GCA_001578235.1_ASM157823v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Mycosphaerella_eumusae-ASM157823v1/GCA_001578235.1_ASM157823v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 01:48:36 2019 # [ok]