# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Ifi-6-16 PF06140.8 AEO53071.1 - 0.0063 16.2 6.5 0.011 15.5 4.5 1.5 1 1 0 1 1 1 1 Interferon-induced 6-16 family DUF4342 PF14242.1 AEO53071.1 - 0.65 9.8 2.5 0.84 9.4 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) F-box PF00646.28 AEO53072.1 - 1.1e-06 28.0 0.6 2.5e-06 26.9 0.4 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 AEO53072.1 - 2.8 7.7 6.1 0.42 10.3 0.5 2.3 2 0 0 2 2 2 0 F-box-like Pertus-S4-tox PF09275.5 AEO53073.1 - 0.013 15.5 0.0 0.014 15.4 0.0 1.1 1 0 0 1 1 1 0 Pertussis toxin S4 subunit Metallophos PF00149.23 AEO53074.1 - 2.2e-39 134.9 1.2 3.7e-39 134.2 0.9 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 AEO53074.1 - 1.9e-13 50.2 0.1 5.2e-13 48.8 0.1 1.8 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.5 AEO53074.1 - 9.7e-12 44.1 0.5 5.3e-11 41.7 0.3 1.9 2 0 0 2 2 2 1 PhoD-like phosphatase fn3 PF00041.16 AEO53074.1 - 0.0016 18.5 0.1 0.0036 17.3 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain RNase_T PF00929.19 AEO53077.1 - 1.4e-12 48.2 0.0 1.5e-11 44.8 0.0 2.0 1 1 0 1 1 1 1 Exonuclease 2-Hacid_dh_C PF02826.14 AEO53078.1 - 4.2e-44 149.8 0.0 2e-43 147.6 0.0 1.9 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 AEO53078.1 - 1.5e-08 34.1 0.0 2.1e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain adh_short PF00106.20 AEO53080.1 - 1.6e-24 86.7 0.3 2.1e-24 86.3 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO53080.1 - 1.7e-12 47.3 0.1 2.9e-12 46.6 0.0 1.4 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 AEO53080.1 - 3e-07 30.4 0.0 3.8e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ras PF00071.17 AEO53081.1 - 4.2e-42 143.2 0.0 6.2e-42 142.7 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AEO53081.1 - 4.8e-15 56.0 0.0 6.9e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AEO53081.1 - 6.5e-11 41.7 0.0 3.2e-10 39.5 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 AEO53081.1 - 0.0011 18.1 0.0 0.0014 17.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 AEO53081.1 - 0.0021 18.0 0.0 0.0031 17.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.1 AEO53081.1 - 0.0032 17.3 0.0 0.0047 16.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 AEO53081.1 - 0.0068 15.8 0.0 0.23 10.9 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 AEO53081.1 - 0.015 15.4 0.0 0.024 14.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 AEO53081.1 - 0.016 14.6 0.0 0.063 12.7 0.0 2.1 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain SRPRB PF09439.5 AEO53081.1 - 0.019 14.1 0.0 0.026 13.7 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NACHT PF05729.7 AEO53081.1 - 0.026 14.2 0.0 0.16 11.6 0.0 2.0 2 0 0 2 2 2 0 NACHT domain DUF258 PF03193.11 AEO53081.1 - 0.029 13.5 0.0 0.043 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 AEO53081.1 - 0.035 14.0 0.0 0.07 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.1 AEO53081.1 - 0.041 13.8 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 AEO53081.1 - 0.052 13.2 0.1 0.072 12.7 0.0 1.1 1 0 0 1 1 1 0 Archaeal ATPase ABC_tran PF00005.22 AEO53081.1 - 0.085 13.1 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_5 PF07728.9 AEO53081.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Glyco_hydro_2_N PF02837.13 AEO53082.1 - 2.1e-11 43.6 0.0 1.3e-10 41.0 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 AEO53082.1 - 2.6e-11 43.9 0.3 1.6e-10 41.4 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 AEO53082.1 - 1.3e-05 24.2 0.0 2.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Qn_am_d_aIII PF09099.5 AEO53082.1 - 0.0071 16.6 0.4 0.48 10.7 0.0 2.7 2 0 0 2 2 2 1 Quinohemoprotein amine dehydrogenase, alpha subunit domain III DUF402 PF04167.8 AEO53082.1 - 0.034 13.9 0.7 2 8.2 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF402) ADH_N PF08240.7 AEO53083.1 - 7.1e-31 106.2 0.8 2.3e-30 104.5 0.1 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AEO53083.1 - 1.6e-23 82.6 0.1 4.1e-23 81.3 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 AEO53083.1 - 1.7e-06 28.9 0.2 7e-06 26.9 0.0 2.1 1 1 1 2 2 2 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 AEO53083.1 - 0.0016 17.8 0.2 0.0091 15.3 0.0 2.1 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_18 PF12847.2 AEO53083.1 - 0.011 16.2 0.0 0.031 14.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain AdoHcyase_NAD PF00670.16 AEO53083.1 - 0.028 14.2 0.2 0.33 10.7 0.2 2.2 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Pyr_redox PF00070.22 AEO53083.1 - 0.029 14.7 0.2 0.2 12.1 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 AEO53083.1 - 0.034 12.6 0.2 0.048 12.1 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein AlaDh_PNT_C PF01262.16 AEO53083.1 - 0.049 13.2 0.3 0.081 12.4 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 AEO53083.1 - 0.056 13.0 0.1 0.088 12.4 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 AEO53083.1 - 0.11 11.6 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Mur_ligase_M PF08245.7 AEO53085.1 - 0.0018 18.3 0.1 0.075 13.0 0.0 2.7 1 1 0 1 1 1 1 Mur ligase middle domain Mitofilin PF09731.4 AEO53086.1 - 9.1e-163 543.0 5.8 1.2e-162 542.6 4.0 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein 4HB_MCP_1 PF12729.2 AEO53086.1 - 0.22 10.8 7.0 0.48 9.7 4.9 1.6 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction Cas_DxTHG PF09455.5 AEO53086.1 - 0.31 10.1 1.4 3.6 6.6 1.7 1.9 2 0 0 2 2 2 0 CRISPR-associated (Cas) DxTHG family LUC7 PF03194.10 AEO53086.1 - 1.1 8.6 14.5 1.6 8.2 6.0 2.6 1 1 1 2 2 2 0 LUC7 N_terminus DUF3373 PF11853.3 AEO53086.1 - 1.2 7.6 2.6 1.7 7.0 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Se-cys_synth_N PF12390.3 AEO53086.1 - 6.1 7.0 8.0 44 4.2 0.2 3.7 2 1 1 3 3 3 0 Selenocysteine synthase N terminal AAA_13 PF13166.1 AEO53086.1 - 6.3 5.1 9.9 12 4.1 6.1 1.6 1 1 1 2 2 2 0 AAA domain DUF2939 PF11159.3 AEO53086.1 - 6.6 6.9 8.0 7.7 6.7 1.9 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF2939) Ras PF00071.17 AEO53087.1 - 7e-59 197.8 0.4 8e-59 197.6 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AEO53087.1 - 3.8e-19 69.3 0.1 7.1e-19 68.4 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 AEO53087.1 - 7.5e-16 57.8 0.1 8.8e-16 57.6 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 AEO53087.1 - 1.4e-08 34.4 0.0 1.9e-08 33.9 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 AEO53087.1 - 1.6e-08 33.9 0.0 2e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 AEO53087.1 - 9.9e-06 25.5 0.0 1.4e-05 25.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 AEO53087.1 - 0.023 13.8 0.2 0.11 11.6 0.0 2.1 2 1 0 3 3 3 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 AEO53087.1 - 0.048 13.8 0.1 1.5 8.9 0.1 2.5 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.15 AEO53087.1 - 0.12 11.0 0.2 9 4.8 0.1 2.3 1 1 1 2 2 2 0 G-protein alpha subunit Syja_N PF02383.13 AEO53088.1 - 1.4e-88 296.7 0.0 1.8e-88 296.3 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain UPF0183 PF03676.9 AEO53090.1 - 1.2e-35 122.8 0.0 4.1e-22 78.3 0.0 4.8 4 1 0 4 4 4 4 Uncharacterised protein family (UPF0183) Kinesin PF00225.18 AEO53091.1 - 1.2e-111 372.6 1.4 1.2e-111 372.6 0.9 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bind PF13931.1 AEO53091.1 - 7e-10 39.2 1.0 7e-10 39.2 0.7 4.9 4 1 0 5 5 5 1 Kinesin-associated microtubule-binding Sin3_corepress PF08295.7 AEO53091.1 - 1.3 8.8 12.1 0.1 12.3 1.6 3.4 3 0 0 3 3 3 0 Sin3 family co-repressor Apolipoprotein PF01442.13 AEO53091.1 - 3.4 7.1 62.0 0.0078 15.7 17.7 4.4 1 1 2 4 4 4 0 Apolipoprotein A1/A4/E domain HAD_2 PF13419.1 AEO53092.1 - 5.3e-28 98.4 0.1 7.2e-28 97.9 0.1 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 AEO53092.1 - 0.00097 19.6 0.0 0.0032 17.9 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RRN9 PF10680.4 AEO53093.1 - 1.6e-19 69.4 0.0 1.1e-18 66.7 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor zf-C2H2_4 PF13894.1 AEO53093.1 - 0.0001 22.3 8.2 0.038 14.3 0.4 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 AEO53093.1 - 0.00042 20.5 5.6 0.022 15.0 0.2 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 AEO53093.1 - 0.00048 20.1 2.4 1.1 9.6 0.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc-finger domain Guanylin PF02058.10 AEO53093.1 - 1.4 8.9 3.5 0.88 9.6 0.3 2.1 2 0 0 2 2 2 0 Guanylin precursor Pescadillo_N PF06732.6 AEO53094.1 - 3.2e-113 377.6 0.3 3.2e-113 377.6 0.2 1.9 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 AEO53094.1 - 1.6e-08 34.5 0.0 8.2e-08 32.2 0.0 2.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PIG-U PF06728.8 AEO53095.1 - 6.2e-122 407.1 26.9 7.2e-122 406.9 18.7 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U BLVR PF06375.6 AEO53096.1 - 0.012 15.4 0.9 0.012 15.4 0.6 2.7 1 1 1 2 2 2 0 Bovine leukaemia virus receptor (BLVR) Tom37_C PF11801.3 AEO53097.1 - 6.1e-17 61.9 0.0 6.7e-16 58.5 0.0 2.1 1 1 0 1 1 1 1 Tom37 C-terminal domain Tom37 PF10568.4 AEO53097.1 - 1.1e-16 60.8 0.0 2.3e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein SSP160 PF06933.6 AEO53097.1 - 7.3 4.4 13.3 12 3.7 9.2 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 tRNA-synt_1 PF00133.17 AEO53098.1 - 4.2e-151 503.9 0.0 5.5e-151 503.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 AEO53098.1 - 1.3e-21 76.7 0.0 1.5e-11 43.5 0.0 3.3 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 AEO53098.1 - 2.2e-15 56.7 0.0 4.2e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA zf-FPG_IleRS PF06827.9 AEO53098.1 - 4.3e-05 23.0 3.9 8.4e-05 22.1 2.7 1.5 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1e PF01406.14 AEO53098.1 - 0.033 13.3 0.0 0.54 9.3 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 AEO53098.1 - 0.12 10.9 0.4 0.86 8.2 0.0 2.3 3 0 0 3 3 3 0 tRNA synthetases class I (K) DZR PF12773.2 AEO53098.1 - 2.8 7.8 4.4 6.5 6.6 3.1 1.6 1 1 0 1 1 1 0 Double zinc ribbon DEAD PF00270.24 AEO53099.1 - 1.5e-24 86.3 0.0 9.8e-14 51.1 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO53099.1 - 1.2e-23 82.7 0.1 3.8e-23 81.1 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AEO53099.1 - 1.3e-05 25.0 0.2 0.0002 21.2 0.0 2.5 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit CDC45 PF02724.9 AEO53099.1 - 0.00025 19.2 3.7 0.00025 19.2 2.5 3.5 3 1 0 3 3 3 1 CDC45-like protein Nop14 PF04147.7 AEO53099.1 - 0.0011 16.9 6.7 0.0011 16.9 4.7 2.4 3 0 0 3 3 3 2 Nop14-like family Zip PF02535.17 AEO53099.1 - 0.74 8.7 7.0 0.23 10.4 0.2 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter RR_TM4-6 PF06459.7 AEO53099.1 - 9.3 6.0 32.1 0.42 10.4 2.4 2.9 3 0 0 3 3 3 0 Ryanodine Receptor TM 4-6 SPRY PF00622.23 AEO53100.1 - 0.00018 21.5 0.0 0.00028 20.9 0.0 1.3 1 0 0 1 1 1 1 SPRY domain Na_Ca_ex PF01699.19 AEO53101.1 - 2.9e-41 140.3 32.9 1.9e-23 82.6 10.3 2.5 2 0 0 2 2 2 2 Sodium/calcium exchanger protein PhoD PF09423.5 AEO53102.1 - 1.2e-07 30.6 0.0 3.9e-07 29.0 0.0 1.7 1 1 0 1 1 1 1 PhoD-like phosphatase Peptidase_S8 PF00082.17 AEO53103.1 - 8.1e-54 182.6 3.5 1.4e-53 181.9 2.5 1.4 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 AEO53103.1 - 2e-28 98.0 0.9 4e-28 97.0 0.6 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain DUF4366 PF14283.1 AEO53103.1 - 0.022 14.2 0.0 0.041 13.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Baculo_p26 PF04766.7 AEO53103.1 - 0.19 10.9 0.0 0.33 10.1 0.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus p26 protein K1377 PF15352.1 AEO53103.1 - 0.63 7.9 2.9 0.88 7.4 2.0 1.1 1 0 0 1 1 1 0 Susceptibility to monomelic amyotrophy PX PF00787.19 AEO53104.1 - 1.6e-20 72.9 0.4 3.3e-20 71.9 0.1 1.8 2 0 0 2 2 1 1 PX domain Vps5 PF09325.5 AEO53104.1 - 1.6e-12 47.1 11.1 2.1e-07 30.4 1.3 2.1 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.13 AEO53104.1 - 3.8e-10 39.6 1.7 9e-10 38.4 1.2 1.5 1 1 0 1 1 1 1 BAR domain Reo_sigmaC PF04582.7 AEO53104.1 - 0.0019 17.4 0.2 0.0028 16.8 0.1 1.1 1 0 0 1 1 1 1 Reovirus sigma C capsid protein IncA PF04156.9 AEO53104.1 - 0.0041 16.7 0.1 0.0041 16.7 0.0 2.1 2 0 0 2 2 2 1 IncA protein Serglycin PF04360.7 AEO53104.1 - 0.0081 15.8 0.2 0.37 10.5 0.0 2.3 2 0 0 2 2 2 1 Serglycin DUF3140 PF11338.3 AEO53104.1 - 0.044 13.8 0.2 0.044 13.8 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3140) DUF3287 PF11690.3 AEO53104.1 - 0.085 12.9 2.1 0.63 10.1 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) eIF3_subunit PF08597.5 AEO53104.1 - 0.39 10.2 8.3 0.099 12.1 2.6 1.9 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit UPF0242 PF06785.6 AEO53104.1 - 0.55 8.8 4.3 0.58 8.7 0.7 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) V_ATPase_I PF01496.14 AEO53104.1 - 2.2 6.0 5.2 6.4 4.5 0.1 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family LETM1 PF07766.8 AEO53105.1 - 1.2e-111 372.0 0.9 2e-111 371.3 0.6 1.3 1 0 0 1 1 1 1 LETM1-like protein SAP PF02037.22 AEO53105.1 - 1.8e-05 24.1 0.0 0.064 12.7 0.0 3.5 3 0 0 3 3 3 2 SAP domain ADK PF00406.17 AEO53106.1 - 4.7e-38 130.4 0.0 3.4e-21 75.7 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.9 AEO53106.1 - 5.9e-14 51.4 0.0 1e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.1 AEO53106.1 - 1.6e-05 25.1 0.0 0.0002 21.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AEO53106.1 - 0.0015 19.3 0.0 0.0063 17.3 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 AEO53106.1 - 0.0039 17.0 0.0 0.23 11.3 0.0 2.5 3 0 0 3 3 3 1 AAA domain Glyco_hydro_76 PF03663.9 AEO53108.1 - 1.1e-24 87.5 2.5 3.2e-16 59.6 0.0 3.9 4 0 0 4 4 4 2 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 AEO53108.1 - 0.014 14.4 0.0 0.025 13.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl Hydrolase Family 88 RRM_1 PF00076.17 AEO53109.1 - 9.2e-16 57.2 0.1 1.8e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO53109.1 - 4.6e-11 42.5 0.0 7.8e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO53109.1 - 2.6e-10 39.9 0.0 5.1e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 AEO53109.1 - 0.021 14.6 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 RNA binding motif SGT1 PF07093.6 AEO53110.1 - 0.0041 15.5 0.3 0.0044 15.4 0.2 1.1 1 0 0 1 1 1 1 SGT1 protein DUF3759 PF12585.3 AEO53110.1 - 0.044 13.6 0.4 0.12 12.3 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3759) PAS_3 PF08447.6 AEO53111.1 - 6.7e-13 48.5 0.0 1.4e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 AEO53111.1 - 8.7e-09 35.6 0.0 2.2e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 AEO53111.1 - 9.6e-06 25.3 0.1 3.1e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 PAS fold PAS_11 PF14598.1 AEO53111.1 - 4.9e-05 23.2 0.0 0.0001 22.1 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.5 AEO53111.1 - 5.2e-05 23.2 0.0 0.00014 21.8 0.0 1.7 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.1 AEO53111.1 - 0.00084 19.1 0.0 0.0083 15.9 0.0 2.3 2 0 0 2 2 2 1 PAS domain DUF4428 PF14471.1 AEO53111.1 - 0.093 12.4 0.3 0.19 11.4 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) Syndecan PF01034.15 AEO53111.1 - 0.13 11.9 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 Syndecan domain FAD-oxidase_C PF02913.14 AEO53112.1 - 6.2e-60 202.5 0.3 1.1e-59 201.7 0.2 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 AEO53112.1 - 4.4e-39 133.1 0.0 9.3e-39 132.0 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain Clr5 PF14420.1 AEO53113.1 - 5.2e-21 74.2 0.6 5.4e-20 71.0 0.1 2.5 2 0 0 2 2 2 1 Clr5 domain Suf PF05843.9 AEO53113.1 - 0.47 10.1 3.3 0.75 9.4 2.3 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.4 AEO53113.1 - 1.1 7.3 16.1 1.6 6.8 11.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Glyco_tranf_2_3 PF13641.1 AEO53115.1 - 7.4e-20 71.7 0.1 1.1e-19 71.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 AEO53115.1 - 9.7e-08 31.4 0.1 2.1e-07 30.4 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 AEO53115.1 - 2e-05 24.3 0.1 0.00054 19.6 0.0 3.0 3 1 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_64 PF09258.5 AEO53115.1 - 0.0002 20.6 0.9 0.00029 20.0 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 64 domain GWT1 PF06423.7 AEO53119.1 - 1.4e-43 148.2 2.1 3.4e-43 147.0 1.5 1.7 1 0 0 1 1 1 1 GWT1 Pkinase PF00069.20 AEO53120.1 - 3.3e-64 216.5 0.0 6.3e-64 215.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO53120.1 - 2e-36 125.4 0.0 3.6e-31 108.1 0.0 2.2 1 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 AEO53120.1 - 1.1e-05 24.5 0.0 0.011 14.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 AEO53120.1 - 0.00065 19.4 0.1 0.0031 17.2 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 AEO53120.1 - 0.016 14.2 0.1 0.03 13.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 AEO53120.1 - 0.017 14.4 0.1 0.033 13.5 0.1 1.3 1 0 0 1 1 1 0 RIO1 family PPP4R2 PF09184.6 AEO53121.1 - 3.2e-11 43.3 4.1 3.2e-11 43.3 2.9 3.6 3 1 0 3 3 3 1 PPP4R2 Pex14_N PF04695.8 AEO53121.1 - 1.4 9.0 26.2 0.039 13.9 3.4 3.6 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Serinc PF03348.10 AEO53121.1 - 1.7 7.2 1.9 3.1 6.4 1.3 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Spt20 PF12090.3 AEO53121.1 - 2.7 7.2 9.6 0.24 10.7 1.7 2.2 2 0 0 2 2 2 0 Spt20 family DUF2681 PF10883.3 AEO53122.1 - 1.7 8.9 4.0 5.1 7.3 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) CRPA PF05745.6 AEO53122.1 - 2.4 7.9 7.6 3.1 7.5 0.1 2.8 3 0 0 3 3 3 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) CLTH PF10607.4 AEO53123.1 - 5.1e-30 104.0 0.0 8.4e-30 103.3 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 AEO53123.1 - 4.2e-17 61.5 0.5 8.1e-17 60.6 0.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 AEO53123.1 - 0.00023 20.8 0.2 0.00038 20.2 0.1 1.4 1 0 0 1 1 1 1 Ring finger domain Rtf2 PF04641.7 AEO53123.1 - 0.00057 19.1 1.3 0.00062 19.0 0.0 1.7 2 0 0 2 2 2 1 Rtf2 RING-finger zf-C3HC4_4 PF15227.1 AEO53123.1 - 0.0012 18.6 0.5 0.0026 17.5 0.4 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 AEO53123.1 - 0.0036 16.9 0.1 0.0056 16.3 0.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO53123.1 - 0.0048 16.5 0.2 0.0076 15.9 0.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 AEO53123.1 - 0.0055 16.7 0.4 0.0091 16.0 0.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Glypican PF01153.14 AEO53123.1 - 0.026 13.1 0.3 0.036 12.6 0.2 1.3 1 0 0 1 1 1 0 Glypican Sigma70_ner PF04546.8 AEO53123.1 - 0.055 13.0 6.3 0.056 13.0 3.2 1.8 2 0 0 2 2 2 0 Sigma-70, non-essential region Rotavirus_VP1 PF12289.3 AEO53123.1 - 0.14 11.8 0.4 0.39 10.3 0.0 1.9 2 0 0 2 2 1 0 Rotavirus VP1 structural protein DUF444 PF04285.7 AEO53123.1 - 0.18 10.4 1.9 0.28 9.7 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF444) Daxx PF03344.10 AEO53123.1 - 0.32 9.4 5.7 0.44 8.9 3.9 1.1 1 0 0 1 1 1 0 Daxx Family Nucleoplasmin PF03066.10 AEO53123.1 - 0.38 10.2 9.9 0.63 9.5 6.9 1.3 1 0 0 1 1 1 0 Nucleoplasmin CDC45 PF02724.9 AEO53123.1 - 0.6 8.0 5.0 0.9 7.5 3.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 AEO53123.1 - 1.2 7.0 9.1 2.2 6.1 6.3 1.4 1 0 0 1 1 1 0 Nop14-like family DUF4611 PF15387.1 AEO53123.1 - 1.3 9.2 8.9 1.6 8.9 3.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Sporozoite_P67 PF05642.6 AEO53123.1 - 4 5.1 7.8 5.6 4.6 5.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PBP1_TM PF14812.1 AEO53123.1 - 4.5 7.6 11.4 8.5 6.7 7.9 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PG_binding_1 PF01471.13 AEO53124.1 - 0.012 15.5 0.0 6.1 6.8 0.0 2.6 2 0 0 2 2 2 0 Putative peptidoglycan binding domain Myosin_tail_1 PF01576.14 AEO53124.1 - 0.019 12.7 6.7 0.026 12.2 4.6 1.1 1 0 0 1 1 1 0 Myosin tail NPV_P10 PF05531.7 AEO53124.1 - 0.051 13.8 1.3 14 6.0 0.1 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Med9 PF07544.8 AEO53124.1 - 0.054 13.2 1.1 7 6.4 0.2 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Spc7 PF08317.6 AEO53124.1 - 0.18 10.4 2.6 0.28 9.7 1.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Tropomyosin_1 PF12718.2 AEO53124.1 - 0.61 9.9 6.4 0.13 12.1 0.7 2.1 1 1 1 2 2 2 0 Tropomyosin like APG6 PF04111.7 AEO53124.1 - 0.97 8.4 4.8 1.5 7.7 3.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 AEO53124.1 - 1 8.9 6.7 1.9 8.0 4.7 1.3 1 0 0 1 1 1 0 IncA protein AAA_13 PF13166.1 AEO53124.1 - 1.1 7.6 2.1 1.6 7.1 1.5 1.1 1 0 0 1 1 1 0 AAA domain zf-Tim10_DDP PF02953.10 AEO53125.1 - 4.8e-20 70.6 2.1 5.4e-20 70.4 1.5 1.0 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 AEO53125.1 - 0.0031 16.9 1.0 0.0045 16.4 0.7 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) tRNA-synt_2 PF00152.15 AEO53126.1 - 5.7e-72 242.3 0.0 6.8e-72 242.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 AEO53126.1 - 3.1e-13 49.3 0.0 5.7e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 AEO53126.1 - 4e-05 22.9 0.0 0.0063 15.7 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) PH_6 PF15406.1 AEO53128.1 - 4.9e-48 161.8 3.3 4.9e-48 161.8 2.3 4.7 4 1 1 5 5 5 1 Pleckstrin homology domain PH PF00169.24 AEO53128.1 - 0.0059 16.7 0.0 0.015 15.4 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_4 PF15404.1 AEO53128.1 - 0.28 10.6 0.0 0.28 10.6 0.0 3.8 4 1 0 4 4 4 0 Pleckstrin homology domain HATPase_c PF02518.21 AEO53129.1 - 4.4e-24 84.3 0.0 8.1e-24 83.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 AEO53129.1 - 2.2e-19 69.4 0.0 4e-15 55.7 0.0 2.5 2 0 0 2 2 2 2 Response regulator receiver domain PAS_9 PF13426.1 AEO53129.1 - 3.4e-11 43.4 0.0 4.1e-09 36.7 0.0 2.7 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.5 AEO53129.1 - 4e-09 36.4 0.0 0.00014 21.8 0.0 2.8 2 0 0 2 2 2 2 PAS fold HisKA PF00512.20 AEO53129.1 - 3.3e-07 30.2 2.1 3.8e-07 30.0 0.1 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS PF00989.19 AEO53129.1 - 2.6e-05 23.9 0.0 0.00012 21.8 0.0 2.1 2 0 0 2 2 2 1 PAS fold GAF_2 PF13185.1 AEO53129.1 - 0.0015 19.0 0.1 0.27 11.7 0.0 2.9 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.1 AEO53129.1 - 0.017 15.2 0.0 0.06 13.4 0.0 2.0 2 0 0 2 2 2 0 GAF domain PAS_8 PF13188.1 AEO53129.1 - 0.026 14.4 0.0 0.098 12.5 0.0 2.0 1 0 0 1 1 1 0 PAS domain Treacle PF03546.9 AEO53131.1 - 0.0046 15.8 0.0 0.0053 15.6 0.0 1.0 1 0 0 1 1 1 1 Treacher Collins syndrome protein Treacle MARVEL PF01284.18 AEO53131.1 - 0.97 9.2 5.7 2.9 7.7 3.8 1.8 2 0 0 2 2 2 0 Membrane-associating domain Aldedh PF00171.17 AEO53133.1 - 5.5e-169 562.3 0.1 6.2e-169 562.2 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 AEO53133.1 - 0.1 11.7 0.0 0.42 9.8 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) Pkinase PF00069.20 AEO53134.1 - 1.8e-23 82.9 0.0 4.8e-23 81.6 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO53134.1 - 7.8e-10 38.2 0.0 2.1e-09 36.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 AEO53134.1 - 0.013 14.5 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AEO53134.1 - 0.029 14.1 0.1 0.051 13.2 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family AAA_16 PF13191.1 AEO53136.1 - 4.9e-05 23.3 2.5 0.00013 21.9 1.7 1.6 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 AEO53136.1 - 0.00099 18.7 0.1 0.0019 17.8 0.1 1.5 1 1 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.9 AEO53136.1 - 0.0017 17.4 0.0 0.0028 16.6 0.0 1.3 1 1 1 2 2 2 1 KAP family P-loop domain AAA_25 PF13481.1 AEO53136.1 - 0.007 15.7 0.6 0.011 15.1 0.4 1.4 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 AEO53136.1 - 0.011 15.9 0.0 0.022 14.9 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AEO53136.1 - 0.017 15.2 0.0 0.021 14.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF1722 PF08349.6 AEO53137.1 - 0.034 14.0 0.1 0.037 13.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) Imm39 PF15600.1 AEO53137.1 - 0.068 13.0 0.0 0.074 12.8 0.0 1.0 1 0 0 1 1 1 0 Immunity protein 39 zf-CCHC PF00098.18 AEO53138.1 - 0.00066 19.4 3.4 0.00098 18.9 2.4 1.3 1 0 0 1 1 1 1 Zinc knuckle DUF3096 PF11295.3 AEO53139.1 - 0.077 12.5 0.0 0.085 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3096) DUF2770 PF10968.3 AEO53139.1 - 9.9 5.9 6.2 1 9.1 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2770) RVT_1 PF00078.22 AEO53142.1 - 4.4e-06 26.2 1.1 5.3e-06 25.9 0.7 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3680 PF12441.3 AEO53143.1 - 0.15 11.9 0.9 0.25 11.2 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3680) THRAP3_BCLAF1 PF15440.1 AEO53143.1 - 3 6.3 15.3 0.06 11.9 3.6 2.2 2 0 0 2 2 2 0 THRAP3/BCLAF1 family Rad1 PF02144.11 AEO53144.1 - 1.9e-87 292.5 0.0 2.2e-87 292.3 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Dexa_ind PF15198.1 AEO53145.1 - 0.12 12.2 0.1 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 Dexamethasone-induced Bromodomain PF00439.20 AEO53146.1 - 3e-26 91.1 0.4 5.8e-26 90.2 0.3 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 AEO53146.1 - 1.2e-09 38.1 0.1 2.8e-09 37.0 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 AEO53146.1 - 3.2e-09 36.7 0.0 6.9e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 AEO53146.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Trehalase PF01204.13 AEO53147.1 - 4.9e-122 408.1 1.8 4.1e-121 405.1 1.3 1.9 1 1 0 1 1 1 1 Trehalase GDE_C PF06202.9 AEO53147.1 - 2.6e-05 23.1 0.3 0.00028 19.7 0.0 2.0 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase Beta_elim_lyase PF01212.16 AEO53148.1 - 5.2e-69 232.5 0.0 6.4e-69 232.2 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 AEO53148.1 - 5.5e-05 22.2 0.0 6.8e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 AEO53148.1 - 0.00016 20.1 0.0 0.00024 19.5 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF605 PF04652.11 AEO53149.1 - 0.65 9.3 10.9 0.93 8.8 7.5 1.3 1 0 0 1 1 1 0 Vta1 like Fungal_trans PF04082.13 AEO53150.1 - 0.015 14.1 0.0 0.017 14.0 0.0 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain Reo_P9 PF06043.6 AEO53150.1 - 0.13 11.2 0.0 0.15 11.0 0.0 1.0 1 0 0 1 1 1 0 Reovirus P9-like family Cep57_MT_bd PF06657.8 AEO53151.1 - 5e-25 87.2 0.1 5e-25 87.2 0.1 7.7 6 2 0 6 6 6 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.1 AEO53151.1 - 1.8e-14 53.3 10.9 1.8e-14 53.3 7.5 8.4 4 3 3 7 7 7 3 Centrosome localisation domain of PPC89 DUF904 PF06005.7 AEO53151.1 - 0.00052 20.2 95.1 0.036 14.3 0.6 9.6 6 2 3 9 9 9 4 Protein of unknown function (DUF904) CCDC155 PF14662.1 AEO53151.1 - 0.0017 17.9 25.0 0.0017 17.9 17.3 5.6 3 1 5 8 8 8 3 Coiled-coil region of CCDC155 MerR_2 PF13591.1 AEO53151.1 - 0.005 16.4 2.5 0.005 16.4 1.7 5.3 6 1 2 8 8 8 1 MerR HTH family regulatory protein ADIP PF11559.3 AEO53151.1 - 0.0061 16.4 13.6 0.0061 16.4 9.4 7.3 3 2 5 8 8 8 2 Afadin- and alpha -actinin-Binding Rootletin PF15035.1 AEO53151.1 - 2.7 7.9 79.7 0.04 13.9 18.6 6.9 4 1 3 7 7 7 0 Ciliary rootlet component, centrosome cohesion Ribophorin_II PF05817.9 AEO53152.1 - 7.3e-21 74.0 3.0 8.4e-20 70.5 2.1 2.0 1 1 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Amidase PF01425.16 AEO53154.1 - 3.5e-71 240.3 0.0 4.2e-71 240.0 0.0 1.1 1 0 0 1 1 1 1 Amidase CDP-OH_P_transf PF01066.16 AEO53155.1 - 1.5e-18 66.9 1.5 1.5e-18 66.9 1.0 2.6 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PX PF00787.19 AEO53156.1 - 3.2e-22 78.4 0.0 5e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 PX domain Peptidase_M28 PF04389.12 AEO53157.1 - 7.6e-38 130.0 0.0 1e-37 129.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PriCT_2 PF08707.6 AEO53157.1 - 0.44 10.4 3.7 0.38 10.6 0.9 2.1 2 1 0 2 2 2 0 Primase C terminal 2 (PriCT-2) DUF3716 PF12511.3 AEO53158.1 - 0.016 14.7 4.5 0.026 14.1 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) NOA36 PF06524.7 AEO53158.1 - 0.034 13.4 1.3 0.038 13.2 0.9 1.1 1 0 0 1 1 1 0 NOA36 protein Zn_clus PF00172.13 AEO53158.1 - 0.71 9.8 11.8 1.6 8.6 8.2 1.6 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 AEO53159.1 - 4e-21 75.6 5.6 4e-21 75.6 3.9 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 AEO53159.1 - 7.8e-11 41.9 1.2 7.8e-11 41.9 0.8 1.7 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 AEO53159.1 - 3.6e-09 36.8 1.4 5.1e-09 36.4 0.3 1.8 2 1 0 2 2 2 1 NADH(P)-binding adh_short_C2 PF13561.1 AEO53159.1 - 3.5e-08 33.4 0.0 5e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 AEO53159.1 - 1.1e-07 31.5 0.2 1.6e-07 31.0 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 AEO53159.1 - 4.6e-05 22.7 0.5 7.2e-05 22.1 0.4 1.4 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 AEO53159.1 - 0.0016 17.3 0.5 0.0031 16.4 0.3 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain TrkA_N PF02254.13 AEO53159.1 - 0.016 15.2 0.1 0.047 13.6 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain Eno-Rase_NADH_b PF12242.3 AEO53159.1 - 0.02 14.6 0.3 0.046 13.5 0.2 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ADH_zinc_N PF00107.21 AEO53159.1 - 0.028 13.9 0.3 0.072 12.6 0.2 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DFP PF04127.10 AEO53159.1 - 0.13 11.8 0.7 0.46 10.0 0.1 2.1 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein IQ PF00612.22 AEO53160.1 - 2.4e-06 26.6 0.9 5.9e-06 25.4 0.6 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif R3H PF01424.17 AEO53161.1 - 2.9e-16 58.8 0.1 6.4e-16 57.8 0.1 1.6 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.12 AEO53161.1 - 1.1e-05 25.2 38.3 1.4e-05 24.9 11.3 13.4 13 1 0 13 13 13 7 NF-X1 type zinc finger PTPA PF03095.10 AEO53163.1 - 7.3e-112 373.4 0.0 8.5e-112 373.1 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein RNase_PH PF01138.16 AEO53164.1 - 2.1e-15 57.1 0.0 3.2e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 AEO53164.1 - 0.097 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 NAD_kinase PF01513.16 AEO53165.1 - 3.2e-71 239.4 0.0 4.3e-71 238.9 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase Homeobox PF00046.24 AEO53166.1 - 1.8e-13 49.8 1.2 3.5e-13 48.9 0.9 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 AEO53166.1 - 0.021 14.4 0.3 0.061 13.0 0.2 1.8 1 0 0 1 1 1 0 Homeobox KN domain Homez PF11569.3 AEO53166.1 - 0.051 12.6 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez zf-GRF PF06839.7 AEO53167.1 - 7.9e-11 41.7 1.9 1.3e-10 40.9 1.3 1.4 1 0 0 1 1 1 1 GRF zinc finger TMF_TATA_bd PF12325.3 AEO53167.1 - 0.085 12.5 4.6 0.39 10.4 2.4 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Sporozoite_P67 PF05642.6 AEO53167.1 - 1.1 6.9 9.0 1.9 6.2 6.2 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ELMO_CED12 PF04727.8 AEO53168.1 - 3.7e-50 169.8 0.0 5.9e-50 169.1 0.0 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.3 AEO53168.1 - 0.00066 19.4 0.0 0.1 12.3 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3361) C2 PF00168.25 AEO53169.1 - 1.1e-70 233.5 1.7 1.3e-19 69.8 0.0 5.6 5 0 0 5 5 5 5 C2 domain NT-C2 PF10358.4 AEO53169.1 - 0.00093 18.6 0.0 0.0052 16.2 0.0 2.3 2 0 0 2 2 2 1 N-terminal C2 in EEIG1 and EHBP1 proteins DUF2404 PF10296.4 AEO53169.1 - 0.072 13.2 0.1 0.31 11.2 0.0 2.2 2 0 0 2 2 2 0 Putative integral membrane protein conserved region (DUF2404) B56 PF01603.15 AEO53169.1 - 0.2 10.2 0.1 0.33 9.4 0.1 1.2 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Atrophin-1 PF03154.10 AEO53169.1 - 0.58 8.2 8.7 1 7.3 6.0 1.3 1 0 0 1 1 1 0 Atrophin-1 family Oxysterol_BP PF01237.13 AEO53171.1 - 6.5e-90 301.1 0.0 8.7e-90 300.7 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein Ammonium_transp PF00909.16 AEO53172.1 - 4.8e-116 387.5 29.2 5.6e-116 387.2 20.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Met_gamma_lyase PF06838.6 AEO53172.1 - 0.057 11.7 0.0 0.084 11.1 0.0 1.1 1 0 0 1 1 1 0 Methionine gamma-lyase SieB PF14163.1 AEO53172.1 - 1.7 8.2 3.2 52 3.3 1.7 2.2 2 0 0 2 2 2 0 Superinfection exclusion protein B DUF2207 PF09972.4 AEO53172.1 - 2.3 6.7 6.1 9 4.7 0.5 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) CRT10 PF08728.5 AEO53173.1 - 1.3e-06 26.7 0.0 0.00076 17.6 0.0 2.1 2 0 0 2 2 2 2 CRT10 Cellulase PF00150.13 AEO53175.1 - 2.2e-36 125.5 0.0 2.5e-36 125.3 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) 7tm_2 PF00002.19 AEO53176.1 - 8.5e-08 31.5 10.4 9.6e-08 31.3 6.4 1.7 1 1 1 2 2 2 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.6 AEO53176.1 - 0.0049 15.8 5.6 0.0085 15.0 3.8 1.4 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor VirB8 PF04335.8 AEO53176.1 - 4.9 6.6 10.2 0.29 10.6 0.3 3.0 3 0 0 3 3 3 0 VirB8 protein TauD PF02668.11 AEO53178.1 - 2.6e-18 66.6 0.2 3.7e-18 66.1 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 AEO53178.1 - 0.027 13.3 0.0 0.037 12.9 0.0 1.2 1 0 0 1 1 1 0 CsiD Zn_clus PF00172.13 AEO53179.1 - 0.0018 18.1 5.7 0.0036 17.1 4.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 AEO53180.1 - 1.1e-08 34.6 0.0 4.3e-08 32.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain FUSC PF04632.7 AEO53180.1 - 0.033 12.6 0.4 0.044 12.2 0.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Exo_endo_phos PF03372.18 AEO53181.1 - 9.2e-21 74.9 0.1 2.3e-20 73.6 0.0 1.6 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Luciferase_cat PF10285.4 AEO53181.1 - 0.00038 19.7 0.0 0.00062 19.0 0.0 1.3 1 0 0 1 1 1 1 Luciferase catalytic domain MFS_2 PF13347.1 AEO53181.1 - 0.12 10.7 2.4 0.17 10.2 1.7 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein WD40 PF00400.27 AEO53182.1 - 1.4e-43 145.2 21.1 3.7e-10 39.2 0.5 6.9 6 1 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 AEO53182.1 - 7.6e-06 24.3 1.0 0.044 11.9 0.1 3.7 2 1 1 3 3 3 2 Nucleoporin Nup120/160 eIF2A PF08662.6 AEO53182.1 - 2.6e-05 24.0 0.0 0.0063 16.2 0.0 2.7 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A BBS2_Mid PF14783.1 AEO53182.1 - 0.002 17.8 0.0 0.37 10.5 0.0 3.0 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region Apc4_WD40 PF12894.2 AEO53182.1 - 0.078 12.4 0.0 8.9 5.9 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain DUF3312 PF11768.3 AEO53182.1 - 0.13 10.4 0.0 2.9 6.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) Pcc1 PF09341.5 AEO53183.1 - 1.1e-25 89.4 1.8 1.4e-25 89.1 1.3 1.2 1 0 0 1 1 1 1 Transcription factor Pcc1 DSPn PF14671.1 AEO53184.1 - 3.2e-44 150.3 0.1 8.3e-41 139.2 0.0 3.8 4 0 0 4 4 4 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 AEO53184.1 - 1.1e-16 60.6 0.0 2e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 AEO53184.1 - 1.5e-06 27.7 0.3 3e-06 26.7 0.0 1.5 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DUF3439 PF11921.3 AEO53184.1 - 0.0083 15.8 5.2 0.024 14.4 3.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) PTPlike_phytase PF14566.1 AEO53184.1 - 0.013 15.5 0.2 0.034 14.2 0.0 1.8 2 0 0 2 2 2 0 Inositol hexakisphosphate Dicty_REP PF05086.7 AEO53184.1 - 0.066 10.9 2.8 0.09 10.5 1.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Y_phosphatase3 PF13350.1 AEO53184.1 - 0.092 12.9 1.3 0.22 11.7 0.0 2.1 2 0 0 2 2 2 0 Tyrosine phosphatase family Y_phosphatase2 PF03162.8 AEO53184.1 - 0.13 11.5 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Myc_N PF01056.13 AEO53185.1 - 0.0061 15.7 0.8 0.011 14.9 0.6 1.3 1 0 0 1 1 1 1 Myc amino-terminal region SWIM PF04434.12 AEO53185.1 - 0.0065 15.9 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 SWIM zinc finger Sulfate_transp PF00916.15 AEO53186.1 - 4e-73 245.8 11.9 7.8e-73 244.8 8.3 1.5 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 AEO53186.1 - 3.6e-30 103.4 2.7 3.6e-30 103.4 1.9 3.1 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 AEO53186.1 - 1.8e-08 33.8 0.0 3.2e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 STAS domain Transferase PF02458.10 AEO53186.1 - 0.0066 14.9 0.0 0.011 14.2 0.0 1.2 1 0 0 1 1 1 1 Transferase family RabGAP-TBC PF00566.13 AEO53187.1 - 2.1e-36 125.4 0.0 9e-30 103.7 0.0 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain HlyIII PF03006.15 AEO53188.1 - 1.3e-57 194.7 20.9 1.6e-57 194.4 14.5 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF1771 PF08590.5 AEO53188.1 - 0.067 13.2 0.9 0.16 12.0 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) An_peroxidase PF03098.10 AEO53188.1 - 0.14 10.4 0.0 0.18 10.1 0.0 1.1 1 0 0 1 1 1 0 Animal haem peroxidase DUF883 PF05957.8 AEO53188.1 - 2 8.8 6.1 9.9 6.6 2.4 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) FimP PF09766.4 AEO53189.1 - 2.2e-28 99.3 9.0 2.8e-28 99.0 6.2 1.1 1 0 0 1 1 1 1 Fms-interacting protein TSC22 PF01166.13 AEO53189.1 - 0.047 13.6 5.7 0.59 10.1 0.1 2.6 2 0 0 2 2 2 0 TSC-22/dip/bun family CENP-F_leu_zip PF10473.4 AEO53189.1 - 0.091 12.6 8.5 0.98 9.2 2.1 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF972 PF06156.8 AEO53189.1 - 0.75 10.1 7.2 11 6.4 1.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Cortex-I_coil PF09304.5 AEO53189.1 - 0.86 9.6 12.0 0.45 10.5 3.4 2.4 2 1 0 2 2 2 0 Cortexillin I, coiled coil DUF4200 PF13863.1 AEO53189.1 - 4.3 7.3 15.3 3.1 7.7 0.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) Atg14 PF10186.4 AEO53189.1 - 6.1 5.7 9.8 3.6 6.4 4.3 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 AEO53189.1 - 8.6 5.3 10.8 3.6 6.5 4.1 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 Glyco_trans_2_3 PF13632.1 AEO53190.1 - 1.6e-14 54.0 0.2 2.3e-14 53.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family group 2 DUF4066 PF13278.1 AEO53191.1 - 1.9e-12 46.8 0.0 2.4e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 AEO53191.1 - 2e-06 27.3 0.0 2.7e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family FKBP_C PF00254.23 AEO53192.1 - 2.2e-32 110.9 0.0 6.4e-31 106.2 0.0 2.6 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF4614 PF15391.1 AEO53192.1 - 9.7 5.9 8.4 1.1 8.9 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) Pkinase PF00069.20 AEO53193.1 - 1.2e-55 188.4 0.0 4e-55 186.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO53193.1 - 1.8e-28 99.3 0.0 1e-19 70.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 AEO53193.1 - 0.0068 16.1 2.6 0.15 11.7 0.2 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 AEO53193.1 - 0.028 13.3 0.0 0.17 10.7 0.0 2.0 2 0 0 2 2 2 0 Kinase-like zf-UBR PF02207.15 AEO53194.1 - 1.5e-18 66.2 15.2 3.8e-18 64.9 10.6 1.7 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 AEO53194.1 - 3.2e-05 23.5 0.1 0.00012 21.7 0.0 2.1 3 0 0 3 3 3 1 ATP-dependent Clp protease adaptor protein ClpS CAP_N PF01213.14 AEO53194.1 - 6.2 6.0 4.3 12 5.1 3.0 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal CDC45 PF02724.9 AEO53194.1 - 8 4.3 5.7 13 3.6 4.0 1.2 1 0 0 1 1 1 0 CDC45-like protein UCR_UQCRX_QCR9 PF05365.7 AEO53195.1 - 2e-26 91.3 1.6 2.2e-26 91.2 1.1 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Mago-bind PF09282.5 AEO53196.1 - 4.1e-15 55.0 4.4 8.8e-15 53.9 3.1 1.6 1 0 0 1 1 1 1 Mago binding POP1 PF06978.6 AEO53196.1 - 0.012 15.2 6.7 0.016 14.8 4.6 1.2 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 Nucleo_P87 PF07267.6 AEO53196.1 - 0.37 9.4 6.1 0.38 9.3 4.2 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 MRL1 PF13003.2 AEO53196.1 - 1.1 9.0 4.4 2.4 7.9 3.0 1.7 1 1 0 1 1 1 0 Ribosomal protein L1 BCS1_N PF08740.6 AEO53197.1 - 2.9e-45 154.1 0.0 4.5e-45 153.5 0.0 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 AEO53197.1 - 8.1e-21 74.6 0.0 1.3e-20 73.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 AEO53197.1 - 1.2e-05 24.4 0.0 2.1e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 AEO53197.1 - 3.7e-05 24.5 0.0 8.5e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 AEO53197.1 - 0.00012 21.8 0.0 0.00036 20.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 AEO53197.1 - 0.00014 20.8 0.0 0.00023 20.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.1 AEO53197.1 - 0.0002 21.5 0.0 0.00041 20.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AEO53197.1 - 0.00056 19.9 0.0 0.0012 18.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 AEO53197.1 - 0.0025 17.6 0.0 0.01 15.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 AEO53197.1 - 0.0028 17.2 0.1 0.008 15.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 AEO53197.1 - 0.0036 17.0 0.1 0.028 14.1 0.0 2.6 1 1 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 AEO53197.1 - 0.0069 15.9 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 AEO53197.1 - 0.013 14.8 0.0 0.037 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 AEO53197.1 - 0.018 14.4 0.1 0.045 13.1 0.0 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 AEO53197.1 - 0.022 15.0 0.0 0.047 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 AEO53197.1 - 0.023 14.6 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 AEO53197.1 - 0.031 14.4 0.0 0.069 13.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 AEO53197.1 - 0.047 13.9 0.0 0.12 12.6 0.0 1.7 2 0 0 2 2 1 0 ABC transporter AAA_21 PF13304.1 AEO53197.1 - 0.052 13.5 0.0 0.086 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 AEO53197.1 - 0.062 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 AEO53197.1 - 0.068 12.8 0.0 0.14 11.8 0.0 1.5 2 0 0 2 2 1 0 Archaeal ATPase Zeta_toxin PF06414.7 AEO53197.1 - 0.07 12.2 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Miro PF08477.8 AEO53197.1 - 0.074 13.5 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein AAA_3 PF07726.6 AEO53197.1 - 0.097 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 AEO53197.1 - 0.12 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Ribosomal_S11 PF00411.14 AEO53198.1 - 2.4e-10 40.5 0.0 4.3e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S11 DUF3439 PF11921.3 AEO53198.1 - 0.084 12.6 1.4 0.15 11.8 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF4160 PF13711.1 AEO53198.1 - 0.35 10.7 3.5 1.2 9.0 2.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4160) Tim44 PF04280.10 AEO53199.1 - 6.8e-34 116.9 0.0 1.6e-33 115.7 0.0 1.7 1 0 0 1 1 1 1 Tim44-like domain DUF1768 PF08719.6 AEO53200.1 - 9.8e-52 174.8 0.0 1.2e-51 174.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) ABC_tran PF00005.22 AEO53201.1 - 5.1e-19 68.9 0.0 9.8e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 AEO53201.1 - 2e-13 50.3 6.9 2e-13 50.3 4.8 2.4 3 1 0 3 3 3 1 ABC transporter transmembrane region DUF258 PF03193.11 AEO53201.1 - 0.0012 18.0 0.0 0.0021 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 AEO53201.1 - 0.0022 18.7 0.0 0.0054 17.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.1 AEO53201.1 - 0.0023 17.9 0.0 0.0047 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 AEO53201.1 - 0.009 15.1 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_23 PF13476.1 AEO53201.1 - 0.0099 16.2 0.2 0.025 14.9 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 AEO53201.1 - 0.02 14.4 0.2 0.053 13.0 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain APS_kinase PF01583.15 AEO53201.1 - 0.093 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_18 PF13238.1 AEO53201.1 - 0.098 12.9 0.1 0.26 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.1 AEO53201.1 - 0.2 10.6 0.0 0.38 9.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain CDC45 PF02724.9 AEO53201.1 - 0.54 8.2 5.6 0.78 7.7 3.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Abhydrolase_5 PF12695.2 AEO53203.1 - 3.4e-24 85.2 0.0 5.4e-24 84.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AEO53203.1 - 2.7e-20 73.2 0.0 3.6e-19 69.5 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO53203.1 - 2.4e-09 37.0 0.0 4.7e-05 23.0 0.0 2.4 1 1 0 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.7 AEO53203.1 - 2.5e-06 26.2 0.2 0.036 12.5 0.0 3.1 2 1 1 3 3 3 3 Acetyl xylan esterase (AXE1) DUF818 PF05677.7 AEO53203.1 - 4.5e-05 22.3 0.0 6.5e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) DLH PF01738.13 AEO53203.1 - 8.2e-05 21.9 0.0 0.0023 17.2 0.0 2.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 AEO53203.1 - 0.0001 21.9 0.0 0.00024 20.7 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 AEO53203.1 - 0.0002 20.9 0.0 0.28 10.5 0.0 2.2 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase FSH1 PF03959.8 AEO53203.1 - 0.00037 20.0 0.0 0.0016 17.9 0.0 1.9 2 0 0 2 2 2 1 Serine hydrolase (FSH1) BAAT_C PF08840.6 AEO53203.1 - 0.0027 17.4 0.1 0.024 14.3 0.0 2.4 3 0 0 3 3 3 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.16 AEO53203.1 - 0.0045 16.2 0.0 0.011 14.9 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 AEO53203.1 - 0.0067 16.2 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Lipase_3 PF01764.20 AEO53203.1 - 0.032 13.8 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.8 AEO53203.1 - 0.033 13.7 0.2 0.18 11.3 0.1 2.0 1 1 0 1 1 1 0 PGAP1-like protein Esterase PF00756.15 AEO53203.1 - 0.1 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DUF2974 PF11187.3 AEO53203.1 - 0.18 11.1 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) zf-LYAR PF08790.6 AEO53204.1 - 3e-08 33.2 0.2 5.6e-08 32.3 0.2 1.5 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger Pex2_Pex12 PF04757.9 AEO53205.1 - 2.2e-43 148.3 0.0 2.8e-43 147.9 0.0 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 AEO53205.1 - 3.8e-12 45.8 7.8 6.5e-12 45.0 5.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 AEO53205.1 - 1.1e-11 44.5 7.3 1.7e-11 43.9 5.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AEO53205.1 - 4.2e-10 39.1 6.2 7e-10 38.4 4.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AEO53205.1 - 9.7e-10 37.9 6.0 1.5e-09 37.3 4.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO53205.1 - 1.9e-08 33.8 5.3 3e-08 33.2 3.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 AEO53205.1 - 1.3e-06 28.2 7.3 2e-06 27.5 5.0 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 AEO53205.1 - 4.7e-05 23.0 2.5 9.8e-05 22.0 1.7 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 AEO53205.1 - 8.2e-05 22.6 7.3 0.00024 21.1 5.1 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 AEO53205.1 - 0.0011 18.6 4.2 0.0022 17.6 2.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 AEO53205.1 - 0.0065 15.9 1.1 0.013 14.9 0.8 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 AEO53205.1 - 0.099 12.2 8.2 0.19 11.3 5.7 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 AEO53205.1 - 0.18 11.6 4.0 0.39 10.6 2.8 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger TerY-C PF15616.1 AEO53205.1 - 0.2 11.6 2.2 0.34 10.8 1.5 1.3 1 0 0 1 1 1 0 TerY-C metal binding domain IBR PF01485.16 AEO53205.1 - 2.7 7.9 7.0 7.3 6.5 4.9 1.7 1 1 0 1 1 1 0 IBR domain EXS PF03124.9 AEO53206.1 - 8.3e-101 337.4 1.4 9.5e-101 337.2 0.9 1.0 1 0 0 1 1 1 1 EXS family NUDIX PF00293.23 AEO53208.1 - 3.7e-13 49.2 0.1 1.5e-12 47.2 0.0 2.0 2 0 0 2 2 2 1 NUDIX domain SelB-wing_3 PF09107.6 AEO53208.1 - 0.1 12.0 0.1 0.21 11.0 0.1 1.4 1 0 0 1 1 1 0 Elongation factor SelB, winged helix Ctr PF04145.10 AEO53209.1 - 1.3e-38 132.2 0.0 1.6e-38 132.0 0.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF4229 PF14012.1 AEO53209.1 - 0.8 9.6 3.5 3.1 7.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) 3-HAO PF06052.7 AEO53210.1 - 4.4e-48 162.5 0.0 5e-48 162.3 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 AEO53210.1 - 4.5e-07 29.2 0.0 6.1e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 AEO53210.1 - 0.00025 20.4 0.0 0.00038 19.9 0.0 1.2 1 0 0 1 1 1 1 Cupin DZR PF12773.2 AEO53210.1 - 0.001 18.7 1.9 0.0017 18.1 1.3 1.3 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.1 AEO53210.1 - 0.0012 17.9 0.3 0.59 9.4 0.0 2.3 2 0 0 2 2 2 2 zinc-ribbon domain AraC_binding PF02311.14 AEO53210.1 - 0.0028 17.3 0.0 0.0046 16.6 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_4 PF08007.7 AEO53210.1 - 0.011 15.0 0.0 0.014 14.6 0.0 1.2 1 1 0 1 1 1 0 Cupin superfamily protein ARD PF03079.9 AEO53210.1 - 0.012 15.5 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family UPF0547 PF10571.4 AEO53210.1 - 0.014 15.0 3.5 0.08 12.6 2.4 2.0 1 1 0 1 1 1 0 Uncharacterised protein family UPF0547 zf-Mss51 PF13824.1 AEO53210.1 - 0.15 11.9 1.2 0.28 11.0 0.9 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Nudix_N_2 PF14803.1 AEO53210.1 - 0.16 11.6 3.9 0.8 9.4 0.1 2.5 2 1 1 3 3 3 0 Nudix N-terminal zf-NADH-PPase PF09297.6 AEO53210.1 - 0.5 9.9 2.9 3.3 7.3 0.2 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain FAA_hydrolase PF01557.13 AEO53211.1 - 1.1e-52 178.6 0.0 1.3e-52 178.4 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family bZIP_2 PF07716.10 AEO53212.1 - 3.4 7.5 6.6 1.1 9.1 2.5 1.7 2 0 0 2 2 2 0 Basic region leucine zipper PWI PF01480.12 AEO53213.1 - 3.2e-30 104.0 0.0 4.6e-30 103.5 0.0 1.2 1 0 0 1 1 1 1 PWI domain NuA4 PF09340.5 AEO53214.1 - 9.8e-24 82.7 0.1 1.7e-23 82.0 0.1 1.4 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 DUF3287 PF11690.3 AEO53214.1 - 0.067 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) BBS2_C PF14782.1 AEO53214.1 - 0.14 10.7 0.0 0.17 10.3 0.0 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal Peptidase_S9 PF00326.16 AEO53215.1 - 9.1e-51 172.0 0.0 1.4e-50 171.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 AEO53215.1 - 6.6e-11 42.1 0.0 1.1e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AEO53215.1 - 4.6e-08 33.2 0.4 1.2e-07 31.8 0.3 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 AEO53215.1 - 0.2 10.0 0.0 0.38 9.2 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Rad21_Rec8_N PF04825.8 AEO53216.1 - 2.5e-35 120.7 0.0 4.7e-35 119.8 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 AEO53216.1 - 7e-08 31.5 0.2 2e-07 30.0 0.0 1.8 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 AEO53216.1 - 0.0037 16.8 0.0 0.076 12.5 0.0 2.3 2 0 0 2 2 2 1 ScpA/B protein E1-E2_ATPase PF00122.15 AEO53217.1 - 2.7e-72 242.5 0.0 4.3e-72 241.8 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 AEO53217.1 - 8.9e-46 155.7 0.2 1.6e-45 154.8 0.1 1.4 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 AEO53217.1 - 1.1e-28 101.1 0.0 9.1e-28 98.1 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 AEO53217.1 - 2.4e-21 74.9 0.0 5e-21 73.9 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 AEO53217.1 - 1.4e-13 50.5 0.0 2.6e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 AEO53217.1 - 3.7e-12 46.8 0.0 1.3e-11 45.0 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 AEO53217.1 - 2.8e-05 23.8 1.1 5.4e-05 22.8 0.7 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase YjgP_YjgQ PF03739.9 AEO53217.1 - 0.088 11.5 0.5 3.3 6.3 0.4 2.2 2 0 0 2 2 2 0 Predicted permease YjgP/YjgQ family COG4 PF08318.7 AEO53218.1 - 1.6e-91 306.5 0.0 5.1e-91 304.8 0.0 1.9 2 0 0 2 2 2 1 COG4 transport protein Dynamin_N PF00350.18 AEO53218.1 - 4.4e-29 101.4 0.0 1.6e-28 99.6 0.0 2.0 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 AEO53218.1 - 1.4e-12 47.0 0.0 2.5e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Miro PF08477.8 AEO53218.1 - 0.0049 17.3 0.0 0.013 15.9 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 AEO53218.1 - 0.0079 16.1 0.0 0.11 12.4 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Macoilin PF09726.4 AEO53218.1 - 0.034 12.4 8.0 0.063 11.5 5.5 1.3 1 0 0 1 1 1 0 Transmembrane protein Med3 PF11593.3 AEO53218.1 - 0.13 11.5 11.2 0.25 10.5 7.8 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal AAA_21 PF13304.1 AEO53218.1 - 0.29 11.0 0.0 0.67 9.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain ThiS PF02597.15 AEO53219.1 - 9.7e-07 29.1 0.1 5.7e-06 26.6 0.1 1.9 1 1 0 1 1 1 1 ThiS family Dynamitin PF04912.9 AEO53220.1 - 1.2e-32 113.2 5.4 7.1e-19 67.8 0.0 3.1 3 0 0 3 3 3 3 Dynamitin FH2 PF02181.18 AEO53220.1 - 2.2e-05 23.5 4.6 0.28 10.0 0.0 3.1 3 0 0 3 3 3 2 Formin Homology 2 Domain MIP-T3 PF10243.4 AEO53220.1 - 0.00012 20.7 0.2 0.00012 20.7 0.1 2.4 3 0 0 3 3 3 1 Microtubule-binding protein MIP-T3 Laminin_II PF06009.7 AEO53220.1 - 0.0024 17.6 12.5 0.041 13.6 0.9 4.4 3 2 1 4 4 4 1 Laminin Domain II Tropomyosin_1 PF12718.2 AEO53220.1 - 0.0035 17.2 19.4 0.22 11.3 2.1 3.5 3 0 0 3 3 3 2 Tropomyosin like BLOC1_2 PF10046.4 AEO53220.1 - 0.0038 17.3 8.2 0.05 13.7 0.6 3.8 3 1 0 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DivIC PF04977.10 AEO53220.1 - 0.012 15.1 12.4 0.016 14.6 1.1 3.5 3 0 0 3 3 3 0 Septum formation initiator TMF_TATA_bd PF12325.3 AEO53220.1 - 0.03 14.0 1.2 0.03 14.0 0.8 3.1 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Perilipin PF03036.11 AEO53220.1 - 0.069 11.9 3.5 0.16 10.8 0.0 2.4 3 0 0 3 3 3 0 Perilipin family DUF3166 PF11365.3 AEO53220.1 - 0.12 12.8 12.7 0.18 12.2 1.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3166) Baculo_PEP_C PF04513.7 AEO53220.1 - 0.26 11.1 1.2 7.4 6.3 0.1 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus RmuC PF02646.11 AEO53220.1 - 0.27 10.0 5.0 4.8 5.9 0.0 2.8 3 0 0 3 3 3 0 RmuC family Snapin_Pallidin PF14712.1 AEO53220.1 - 0.4 11.0 6.3 2.2 8.6 0.4 3.8 3 1 0 3 3 3 0 Snapin/Pallidin Phage_GP20 PF06810.6 AEO53220.1 - 0.45 9.9 9.5 0.14 11.5 0.3 3.1 3 0 0 3 3 3 0 Phage minor structural protein GP20 GAS PF13851.1 AEO53220.1 - 0.76 8.9 8.6 3 6.9 0.5 3.2 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding COG2 PF06148.6 AEO53220.1 - 1.4 8.7 5.5 7.8 6.3 0.2 3.2 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Phage_Mu_Gam PF07352.7 AEO53220.1 - 1.5 8.3 12.5 0.45 10.0 1.2 2.7 3 0 0 3 3 3 0 Bacteriophage Mu Gam like protein IFT57 PF10498.4 AEO53220.1 - 1.8 7.2 8.7 0.25 10.0 0.3 2.8 2 1 1 3 3 3 0 Intra-flagellar transport protein 57 DUF1192 PF06698.6 AEO53220.1 - 1.8 8.4 16.1 0.55 10.0 1.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Spc24 PF08286.6 AEO53220.1 - 3.6 7.3 11.0 12 5.6 0.4 3.4 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 Dor1 PF04124.7 AEO53220.1 - 4.5 5.6 6.3 7.7 4.8 0.1 2.7 3 0 0 3 3 3 0 Dor1-like family DUF1664 PF07889.7 AEO53220.1 - 4.5 7.0 5.5 6.5 6.5 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.14 AEO53220.1 - 5.1 4.8 5.7 1.9 6.2 0.4 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF904 PF06005.7 AEO53220.1 - 5.4 7.3 14.1 7.8 6.8 0.2 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF904) Prefoldin_2 PF01920.15 AEO53220.1 - 5.8 6.7 18.1 6.6 6.5 1.1 4.9 4 2 1 5 5 5 0 Prefoldin subunit Mnd1 PF03962.10 AEO53220.1 - 5.9 6.5 15.3 1.8 8.1 0.4 3.0 2 1 0 2 2 2 0 Mnd1 family DUF4200 PF13863.1 AEO53220.1 - 6.6 6.7 12.8 2.7 7.9 1.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) FlgN PF05130.7 AEO53220.1 - 6.8 6.9 20.4 0.62 10.3 2.3 3.2 2 1 1 3 3 3 0 FlgN protein GrpE PF01025.14 AEO53220.1 - 7.3 6.1 13.1 7.4 6.0 0.9 3.5 3 1 0 3 3 3 0 GrpE THOC7 PF05615.8 AEO53220.1 - 7.6 6.8 13.0 0.32 11.2 0.5 3.3 3 1 0 3 3 3 0 Tho complex subunit 7 TPR_MLP1_2 PF07926.7 AEO53220.1 - 9.4 5.9 17.7 1.2 8.8 2.3 3.3 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein RTC4 PF14474.1 AEO53221.1 - 3.8e-32 110.8 0.0 6.1e-32 110.1 0.0 1.3 1 0 0 1 1 1 1 RTC4-like domain PP2C PF00481.16 AEO53222.1 - 3.9e-57 193.5 0.0 6.3e-57 192.8 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.2 AEO53222.1 - 2.4e-52 173.8 65.7 1.5e-08 34.0 1.2 13.4 7 3 9 16 16 16 13 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AEO53222.1 - 6e-44 147.6 59.9 1.4e-11 43.9 1.1 10.4 6 3 7 14 14 14 10 Leucine rich repeat Guanylate_cyc PF00211.15 AEO53222.1 - 2.5e-27 95.4 0.0 4.5e-27 94.6 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 AEO53222.1 - 2.5e-26 87.6 62.3 0.092 12.8 0.1 20.2 19 1 2 21 21 21 11 Leucine Rich Repeat Ad_cyc_g-alpha PF08509.6 AEO53222.1 - 2.7e-18 65.0 2.5 2.7e-18 65.0 1.8 3.3 3 0 0 3 3 3 1 Adenylate cyclase G-alpha binding domain LRR_7 PF13504.1 AEO53222.1 - 2.3e-13 47.9 59.7 0.049 13.8 0.1 17.9 19 0 0 19 19 19 3 Leucine rich repeat RA PF00788.18 AEO53222.1 - 3.4e-08 33.8 0.0 9.3e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain LRR_6 PF13516.1 AEO53222.1 - 4.6e-07 29.2 49.4 3.6 7.9 0.1 15.6 17 0 0 17 17 17 2 Leucine Rich repeat LRR_9 PF14580.1 AEO53222.1 - 0.0018 17.8 14.3 1.4 8.4 0.1 4.4 2 1 2 4 4 4 3 Leucine-rich repeat PP2C_2 PF13672.1 AEO53222.1 - 0.0046 16.3 0.1 0.011 15.1 0.1 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C ABC_membrane_2 PF06472.10 AEO53223.1 - 5.8e-98 327.4 2.3 1.3e-97 326.2 0.1 2.3 3 0 0 3 3 3 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 AEO53223.1 - 1.7e-14 54.3 0.0 5.1e-14 52.7 0.0 1.9 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 AEO53223.1 - 0.0023 17.9 0.1 0.012 15.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 AEO53223.1 - 0.021 13.8 0.0 0.053 12.5 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_29 PF13555.1 AEO53223.1 - 0.037 13.5 0.0 0.09 12.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 AEO53223.1 - 0.051 13.5 0.6 0.16 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_17 PF13207.1 AEO53223.1 - 0.055 14.2 0.1 0.38 11.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 AEO53223.1 - 0.066 13.4 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 AEO53223.1 - 0.072 12.5 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 AEO53223.1 - 0.083 12.0 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.1 AEO53223.1 - 6.5 7.0 8.2 74 3.5 5.7 2.8 1 1 0 1 1 1 0 AAA domain NIF PF03031.13 AEO53224.1 - 2.5e-51 173.5 0.2 3.3e-51 173.1 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Sec61_beta PF03911.11 AEO53225.1 - 8.9e-21 73.4 1.5 1.1e-20 73.0 1.0 1.1 1 0 0 1 1 1 1 Sec61beta family DUF3983 PF13137.1 AEO53225.1 - 1 9.1 3.8 1.6 8.4 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3983) DUF1180 PF06679.7 AEO53225.1 - 5.7 6.7 6.9 11 5.8 4.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) UCH PF00443.24 AEO53227.1 - 1.6e-63 214.3 0.0 2.4e-63 213.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AEO53227.1 - 8.6e-32 110.7 0.0 1.1e-24 87.4 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 AEO53227.1 - 0.034 13.4 3.0 40 3.3 3.4 3.4 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase CAF-1_p150 PF11600.3 AEO53227.1 - 0.055 12.8 26.9 0.024 14.0 15.6 2.4 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Yos1 PF08571.5 AEO53228.1 - 1.5e-28 98.7 0.5 1.6e-28 98.5 0.3 1.0 1 0 0 1 1 1 1 Yos1-like Aldo_ket_red PF00248.16 AEO53229.1 - 4.5e-50 170.0 0.0 5.2e-50 169.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family LRR_4 PF12799.2 AEO53230.1 - 1.5e-43 145.7 23.8 6.8e-12 44.7 0.8 6.6 5 1 2 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AEO53230.1 - 3.2e-31 106.8 63.9 2e-08 33.8 0.8 4.8 1 1 7 8 8 8 8 Leucine rich repeat LRR_9 PF14580.1 AEO53230.1 - 1.1e-12 47.9 8.8 3.1e-05 23.5 0.0 3.1 1 1 1 3 3 3 3 Leucine-rich repeat LRR_7 PF13504.1 AEO53230.1 - 5.6e-12 43.7 18.3 2.3 8.7 0.0 9.2 9 0 0 9 9 9 4 Leucine rich repeat LRR_6 PF13516.1 AEO53230.1 - 1.5e-10 40.0 19.8 0.17 12.0 0.2 9.7 7 3 4 11 11 11 3 Leucine Rich repeat LRR_1 PF00560.28 AEO53230.1 - 6.4e-09 34.6 27.7 0.32 11.1 0.2 10.6 12 0 0 12 12 12 3 Leucine Rich Repeat IF4E PF01652.13 AEO53230.1 - 0.12 11.8 0.0 22 4.5 0.0 3.1 3 1 0 3 3 3 0 Eukaryotic initiation factor 4E Abhydrolase_5 PF12695.2 AEO53231.1 - 9.2e-08 31.9 0.0 1.4e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AEO53231.1 - 2.5e-06 27.5 1.9 8.6e-06 25.7 0.1 2.4 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO53231.1 - 0.0066 16.0 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold LIP PF03583.9 AEO53231.1 - 0.084 12.0 0.0 0.34 10.0 0.0 1.9 2 0 0 2 2 2 0 Secretory lipase Abhydrolase_3 PF07859.8 AEO53231.1 - 0.087 12.3 0.0 0.19 11.3 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold BTB PF00651.26 AEO53232.1 - 1.9e-10 40.7 0.1 7e-10 38.8 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Skp1_POZ PF03931.10 AEO53232.1 - 0.0084 16.1 0.0 0.063 13.3 0.0 2.1 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain PCI PF01399.22 AEO53233.1 - 8.5e-13 48.5 0.0 7.8e-12 45.4 0.0 2.5 2 0 0 2 2 2 1 PCI domain TPR_11 PF13414.1 AEO53233.1 - 0.041 13.5 1.5 0.061 12.9 0.1 2.0 2 0 0 2 2 2 0 TPR repeat Ribosomal_L18ae PF01775.12 AEO53234.1 - 2.1e-59 198.8 0.4 2.6e-59 198.5 0.3 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain Acetyltransf_3 PF13302.1 AEO53235.1 - 4.6e-36 124.1 0.0 6.4e-36 123.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 AEO53235.1 - 4e-07 30.0 0.0 0.00043 20.2 0.0 2.1 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 AEO53235.1 - 0.11 12.5 0.0 20 5.2 0.0 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Nop14 PF04147.7 AEO53238.1 - 0.012 13.6 17.4 0.015 13.2 12.1 1.2 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 AEO53238.1 - 0.065 11.7 19.6 0.085 11.3 13.6 1.1 1 0 0 1 1 1 0 Daxx Family Plasmodium_Vir PF05795.6 AEO53238.1 - 0.1 11.8 0.1 0.12 11.5 0.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Spore_coat_CotO PF14153.1 AEO53238.1 - 0.13 11.6 8.8 0.18 11.2 6.1 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DUF1656 PF07869.7 AEO53238.1 - 0.45 10.3 3.1 0.85 9.4 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) Sigma70_ner PF04546.8 AEO53238.1 - 0.47 10.0 12.6 0.89 9.1 8.7 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region BUD22 PF09073.5 AEO53238.1 - 0.55 9.2 14.7 0.87 8.5 10.2 1.2 1 0 0 1 1 1 0 BUD22 CobT PF06213.7 AEO53238.1 - 1.1 8.3 20.4 1.7 7.7 14.2 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF1510 PF07423.6 AEO53238.1 - 2.2 7.5 15.3 3.3 7.0 10.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 AEO53238.1 - 2.4 6.0 13.4 3.2 5.6 9.3 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.7 AEO53238.1 - 2.5 7.2 18.0 3.2 6.9 12.5 1.1 1 0 0 1 1 1 0 SDA1 Lin-8 PF03353.10 AEO53238.1 - 2.7 7.1 9.9 4.3 6.5 6.8 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Pox_Ag35 PF03286.9 AEO53238.1 - 3.1 7.2 9.2 5.3 6.5 6.4 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RNA_pol_3_Rpc31 PF11705.3 AEO53238.1 - 4 7.3 18.4 7.7 6.3 12.8 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Radial_spoke PF04712.7 AEO53238.1 - 4.2 6.0 16.2 6.2 5.4 11.2 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein Ycf1 PF05758.7 AEO53238.1 - 4.2 4.9 5.6 5.1 4.6 3.8 1.1 1 0 0 1 1 1 0 Ycf1 Paf1 PF03985.8 AEO53238.1 - 4.3 5.9 20.3 6 5.4 14.1 1.1 1 0 0 1 1 1 0 Paf1 BTV_NS2 PF04514.7 AEO53238.1 - 4.9 5.9 9.3 6.8 5.4 6.4 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Prothymosin PF03247.9 AEO53238.1 - 5.3 7.2 35.2 9.4 6.4 24.4 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family NOA36 PF06524.7 AEO53238.1 - 8.9 5.4 14.7 13 4.9 10.2 1.1 1 0 0 1 1 1 0 NOA36 protein Usp PF00582.21 AEO53238.1 - 9.8 6.3 7.1 19 5.4 4.9 1.4 1 0 0 1 1 1 0 Universal stress protein family ATP-synt_E PF05680.7 AEO53239.1 - 8.6e-27 92.9 0.3 9.2e-27 92.8 0.2 1.0 1 0 0 1 1 1 1 ATP synthase E chain ABC_tran_2 PF12848.2 AEO53239.1 - 0.033 14.0 3.1 0.047 13.5 2.2 1.2 1 0 0 1 1 1 0 ABC transporter T2SM PF04612.7 AEO53239.1 - 0.073 12.8 0.2 0.076 12.8 0.1 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M DUF3813 PF12758.2 AEO53239.1 - 0.11 12.7 5.7 0.13 12.4 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3813) ABC_trans_N PF14510.1 AEO53239.1 - 0.12 12.4 0.2 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 ABC-transporter extracellular N-terminal Chordopox_A13L PF05961.6 AEO53239.1 - 0.21 11.5 0.5 0.72 9.8 0.0 1.8 1 1 1 2 2 2 0 Chordopoxvirus A13L protein WD40 PF00400.27 AEO53240.1 - 8.7e-17 60.3 6.6 2.1e-07 30.5 0.1 5.0 6 0 0 6 6 6 3 WD domain, G-beta repeat MRP-L46 PF11788.3 AEO53240.1 - 0.017 15.7 2.5 0.017 15.7 1.7 2.1 2 1 0 2 2 2 0 39S mitochondrial ribosomal protein L46 Dynein_IC2 PF11540.3 AEO53240.1 - 0.16 11.3 0.9 2.2 7.6 0.6 2.5 2 0 0 2 2 2 0 Cytoplasmic dynein 1 intermediate chain 2 Aldo_ket_red PF00248.16 AEO53241.1 - 5.1e-06 25.5 0.0 0.00025 19.9 0.0 2.2 1 1 1 2 2 2 2 Aldo/keto reductase family MaoC_dehydratas PF01575.14 AEO53243.1 - 1.3e-22 79.4 0.0 2.4e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 AEO53243.1 - 1.9e-08 34.1 0.0 8.8e-06 25.5 0.0 2.2 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase LRR_4 PF12799.2 AEO53244.1 - 5.5e-21 73.7 4.0 0.00014 21.4 1.1 5.2 5 0 0 5 5 5 4 Leucine Rich repeats (2 copies) CAP_GLY PF01302.20 AEO53244.1 - 4.8e-20 71.0 0.0 8.5e-20 70.2 0.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain LRR_8 PF13855.1 AEO53244.1 - 1.5e-09 37.4 7.9 0.021 14.5 3.5 5.0 3 1 2 5 5 5 4 Leucine rich repeat LRR_1 PF00560.28 AEO53244.1 - 9e-09 34.1 7.7 0.5 10.5 0.0 6.8 7 0 0 7 7 7 1 Leucine Rich Repeat LRR_6 PF13516.1 AEO53244.1 - 4.9e-08 32.2 5.8 5.2 7.4 0.0 6.7 7 0 0 7 7 7 3 Leucine Rich repeat LRR_7 PF13504.1 AEO53244.1 - 1e-05 24.9 9.5 26 5.6 0.0 6.8 6 0 0 6 6 6 0 Leucine rich repeat LRR_9 PF14580.1 AEO53244.1 - 0.0012 18.4 0.0 0.66 9.5 0.0 3.3 2 1 2 4 4 4 1 Leucine-rich repeat PI-PLC-X PF00388.14 AEO53246.1 - 8.8e-07 28.4 0.0 1.5e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain MTBP_C PF14920.1 AEO53246.1 - 0.062 12.7 0.4 0.11 11.9 0.3 1.3 1 0 0 1 1 1 0 MDM2-binding SR-25 PF10500.4 AEO53246.1 - 2.8 7.3 6.0 6 6.2 4.1 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein GPI-anchored PF10342.4 AEO53247.1 - 7.5e-19 68.0 0.1 7.5e-19 68.0 0.1 3.5 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 AEO53247.1 - 0.0078 15.7 0.1 0.024 14.1 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) Apt1 PF10351.4 AEO53247.1 - 0.31 9.8 4.8 0.4 9.4 3.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF601 PF04642.7 AEO53247.1 - 2.8 7.2 7.1 4 6.7 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF601 Tubulin PF00091.20 AEO53248.1 - 1.4e-66 224.3 0.0 1.8e-66 224.0 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 AEO53248.1 - 4.1e-43 146.4 0.0 6.3e-43 145.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 AEO53248.1 - 0.00051 19.5 0.0 0.00088 18.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain RRM_1 PF00076.17 AEO53249.1 - 1.9e-11 43.4 0.0 1.9e-08 33.8 0.0 2.9 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO53249.1 - 2.1e-09 37.0 0.0 0.0017 18.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO53249.1 - 7.9e-07 28.9 0.0 4.6e-05 23.3 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Sds3 PF08598.6 AEO53250.1 - 1.9e-31 109.2 2.4 1.9e-31 109.2 1.7 3.7 3 2 0 3 3 3 1 Sds3-like Coiled-coil_56 PF09813.4 AEO53251.1 - 5e-06 26.4 0.0 5e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 DUF3453 PF11935.3 AEO53252.1 - 4.3e-72 242.3 0.0 7.9e-72 241.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) MFS_1 PF07690.11 AEO53255.1 - 4e-21 75.1 48.8 1.5e-18 66.6 18.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO53255.1 - 6.1e-17 61.3 23.1 2.2e-16 59.4 16.0 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter IBN_N PF03810.14 AEO53256.1 - 3.2e-14 52.5 0.4 3.8e-13 49.1 0.6 2.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.7 AEO53256.1 - 5e-05 23.2 2.9 0.00096 19.0 0.0 3.8 3 1 1 4 4 4 1 Exportin 1-like protein DNA_ligase_A_N PF04675.9 AEO53256.1 - 0.0025 17.6 0.1 0.0066 16.2 0.1 1.7 1 0 0 1 1 1 1 DNA ligase N terminus HEAT PF02985.17 AEO53256.1 - 0.015 15.3 0.8 13 6.1 0.0 4.5 4 0 0 4 4 4 0 HEAT repeat MFS_1_like PF12832.2 AEO53257.1 - 4.3e-18 64.8 0.4 4.3e-18 64.8 0.3 2.5 3 0 0 3 3 3 1 MFS_1 like family Cytochrom_B558a PF05038.8 AEO53257.1 - 0.14 11.7 1.6 0.22 11.1 0.0 2.2 2 0 0 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit Pribosyltran PF00156.22 AEO53258.1 - 2.4e-15 56.3 0.0 3.8e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 AEO53258.1 - 0.0028 16.8 0.0 0.0045 16.2 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Glyco_hydro_47 PF01532.15 AEO53259.1 - 1.3e-134 449.2 0.0 1.6e-134 448.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.17 AEO53259.1 - 0.15 11.7 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 PA domain Zip PF02535.17 AEO53261.1 - 1.4 7.8 8.4 0.11 11.4 2.1 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter Fungal_trans PF04082.13 AEO53263.1 - 1e-09 37.6 0.1 2.2e-09 36.6 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO53263.1 - 3.1e-06 26.9 10.2 3.1e-06 26.9 7.1 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.1 AEO53265.1 - 5.9e-25 88.4 0.0 7.8e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 AEO53265.1 - 8e-25 87.6 5.1 1.1e-24 87.2 3.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO53265.1 - 2.5e-12 46.8 1.6 4e-12 46.1 1.1 1.2 1 0 0 1 1 1 1 KR domain Globin PF00042.17 AEO53267.1 - 7.7e-11 42.3 0.0 1.5e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Globin NAD_binding_1 PF00175.16 AEO53267.1 - 7.7e-08 32.8 0.0 1.4e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 AEO53267.1 - 9.5e-08 32.0 0.0 1.6e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Protoglobin PF11563.3 AEO53267.1 - 0.0021 17.7 0.0 0.0035 17.0 0.0 1.4 1 0 0 1 1 1 1 Protoglobin NAD_binding_6 PF08030.7 AEO53267.1 - 0.17 11.7 0.9 0.87 9.4 0.1 2.3 3 0 0 3 3 3 0 Ferric reductase NAD binding domain SET PF00856.23 AEO53268.1 - 1e-06 29.1 0.0 5.4e-05 23.5 0.0 2.4 1 1 0 1 1 1 1 SET domain DUF605 PF04652.11 AEO53269.1 - 0.03 13.7 24.1 0.083 12.2 2.6 2.2 2 0 0 2 2 2 0 Vta1 like TFIIF_alpha PF05793.7 AEO53269.1 - 5 5.3 7.3 8.5 4.6 5.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) ZZ PF00569.12 AEO53270.1 - 1.9e-11 43.3 8.2 3.3e-11 42.5 5.7 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_1 PF00036.27 AEO53270.1 - 3e-10 38.6 2.8 0.00037 19.5 0.0 3.8 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 AEO53270.1 - 4.1e-08 32.4 3.5 0.00014 21.4 0.1 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 AEO53270.1 - 5.6e-07 29.6 6.5 0.0048 17.0 0.1 4.0 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_8 PF13833.1 AEO53270.1 - 0.0013 18.2 1.4 0.91 9.1 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain pair Iron_traffic PF04362.9 AEO53270.1 - 0.068 12.6 0.0 1 8.8 0.0 2.3 2 0 0 2 2 2 0 Bacterial Fe(2+) trafficking C1_3 PF07649.7 AEO53270.1 - 0.48 10.5 9.1 0.83 9.7 6.3 1.4 1 0 0 1 1 1 0 C1-like domain EF-hand_5 PF13202.1 AEO53270.1 - 6.7 6.2 9.6 0.26 10.7 0.1 3.2 3 0 0 3 3 3 0 EF hand Vps53_N PF04100.7 AEO53271.1 - 7.2e-100 334.4 0.0 1.1e-99 333.8 0.0 1.2 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF2450 PF10475.4 AEO53271.1 - 9.6e-06 24.7 2.5 1.7e-05 23.9 1.7 1.3 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) DUF2451 PF10474.4 AEO53271.1 - 0.0038 17.0 0.1 0.0087 15.8 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Spc7 PF08317.6 AEO53271.1 - 0.0057 15.3 0.3 0.012 14.3 0.2 1.5 1 0 0 1 1 1 1 Spc7 kinetochore protein Sec15 PF04091.7 AEO53271.1 - 0.025 13.9 0.1 0.057 12.7 0.1 1.5 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like Rbsn PF11464.3 AEO53271.1 - 0.031 13.8 0.3 0.1 12.1 0.2 1.9 1 0 0 1 1 1 0 Rabenosyn Rab binding domain Zw10 PF06248.8 AEO53271.1 - 0.042 12.0 5.0 0.0087 14.2 1.0 1.6 2 0 0 2 2 2 0 Centromere/kinetochore Zw10 NPR2 PF06218.6 AEO53272.1 - 1.7e-102 343.3 0.0 2e-102 343.0 0.0 1.0 1 0 0 1 1 1 1 Nitrogen permease regulator 2 tRNA-synt_1b PF00579.20 AEO53273.1 - 8.6e-80 267.9 0.5 3.8e-79 265.8 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (W and Y) CybS PF05328.7 AEO53274.1 - 2e-52 176.3 0.0 2.6e-52 175.9 0.0 1.1 1 0 0 1 1 1 1 CybS Sdh_cyt PF01127.17 AEO53274.1 - 0.018 14.8 0.5 0.12 12.1 0.3 2.0 1 1 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Fungal_trans PF04082.13 AEO53275.1 - 8.1e-06 24.9 0.0 1.3e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO53275.1 - 8.1e-06 25.6 11.9 1.4e-05 24.8 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CNTF PF01110.12 AEO53275.1 - 0.073 12.3 0.1 0.29 10.4 0.0 1.8 2 0 0 2 2 2 0 Ciliary neurotrophic factor DUF3419 PF11899.3 AEO53276.1 - 2.2e-157 523.6 0.0 2.9e-157 523.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.1 AEO53276.1 - 1.1e-07 31.7 0.0 2.4e-06 27.3 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO53276.1 - 6.3e-07 29.4 0.1 0.00048 20.1 0.0 3.8 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO53276.1 - 7.8e-06 25.5 0.0 0.00012 21.6 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO53276.1 - 9.9e-06 25.9 0.0 4.6e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO53276.1 - 0.00055 20.3 0.0 4.4 7.8 0.0 3.9 4 0 0 4 4 4 1 Methyltransferase domain Ubie_methyltran PF01209.13 AEO53276.1 - 0.0008 18.5 0.0 1.1 8.3 0.0 2.8 2 1 1 3 3 3 2 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 AEO53276.1 - 0.069 13.5 0.0 0.24 11.8 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain SR-25 PF10500.4 AEO53276.1 - 0.21 10.9 6.6 0.33 10.3 4.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SoxE PF06525.6 AEO53276.1 - 0.37 10.0 1.6 0.62 9.3 1.1 1.2 1 0 0 1 1 1 0 Sulfocyanin (SoxE) Ada3 PF10198.4 AEO53278.1 - 3.8e-47 159.3 0.2 1e-46 157.9 0.0 1.9 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 DnaJ PF00226.26 AEO53278.1 - 0.031 13.9 0.0 0.079 12.7 0.0 1.7 1 0 0 1 1 1 0 DnaJ domain DUF1003 PF06210.6 AEO53278.1 - 1.2 9.1 2.8 3.5 7.5 2.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) zf-RING_2 PF13639.1 AEO53279.1 - 3.2e-12 46.0 5.6 3.2e-12 46.0 3.9 1.7 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 AEO53279.1 - 3.4e-07 30.1 6.6 6.7e-07 29.2 4.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO53279.1 - 1.4e-06 27.9 4.5 2.4e-06 27.1 3.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 AEO53279.1 - 9.7e-06 25.1 6.1 1.9e-05 24.2 4.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 AEO53279.1 - 1.5e-05 24.9 1.9 1.5e-05 24.9 1.3 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 AEO53279.1 - 2.2e-05 24.0 3.2 4e-05 23.1 2.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 AEO53279.1 - 0.0024 17.6 1.9 0.0078 16.0 0.5 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 AEO53279.1 - 0.016 14.8 1.2 0.016 14.8 0.8 2.3 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 AEO53279.1 - 0.017 15.0 7.4 0.033 14.0 5.1 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 AEO53279.1 - 0.16 11.9 3.8 0.53 10.2 2.7 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 AEO53279.1 - 0.2 11.6 3.7 0.43 10.6 2.6 1.6 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.1 AEO53279.1 - 0.26 10.9 2.9 0.46 10.1 2.0 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.24 AEO53279.1 - 0.27 10.9 3.2 0.47 10.1 2.2 1.4 1 0 0 1 1 1 0 PHD-finger zf-Nse PF11789.3 AEO53279.1 - 0.95 9.0 3.8 1.9 8.0 2.6 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.6 AEO53279.1 - 1.2 9.1 3.5 2.6 8.0 2.4 1.6 1 0 0 1 1 1 0 RING-like domain DUF726 PF05277.7 AEO53280.1 - 3.5e-110 368.1 0.8 3.5e-110 368.1 0.6 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF726) Thioesterase PF00975.15 AEO53280.1 - 1.7e-05 25.1 0.1 5.3e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 Thioesterase domain DUF605 PF04652.11 AEO53280.1 - 4.5e-05 23.0 10.0 4.5e-05 23.0 6.9 1.8 2 0 0 2 2 2 1 Vta1 like Abhydrolase_6 PF12697.2 AEO53280.1 - 4.8e-05 23.3 0.1 4.8e-05 23.3 0.1 2.5 3 1 1 4 4 4 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO53280.1 - 0.0012 18.5 0.0 0.0042 16.8 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family PE-PPE PF08237.6 AEO53280.1 - 0.01 15.2 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 PE-PPE domain Cutinase PF01083.17 AEO53280.1 - 0.054 13.2 0.0 0.098 12.3 0.0 1.3 1 0 0 1 1 1 0 Cutinase Lipase_3 PF01764.20 AEO53280.1 - 0.056 13.0 0.0 0.5 9.9 0.0 2.1 2 0 0 2 2 2 0 Lipase (class 3) DUF900 PF05990.7 AEO53280.1 - 0.091 12.0 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Noc2 PF03715.8 AEO53281.1 - 2.3e-121 404.2 0.1 7.1e-121 402.6 0.0 1.8 2 0 0 2 2 2 1 Noc2p family VPS28 PF03997.7 AEO53282.1 - 2.7e-55 186.9 0.0 3.2e-55 186.6 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein GvpG PF05120.7 AEO53282.1 - 0.0083 15.9 4.4 0.048 13.4 0.2 2.3 2 0 0 2 2 2 2 Gas vesicle protein G DUF2404 PF10296.4 AEO53283.1 - 0.00028 20.9 0.0 0.0015 18.6 0.0 1.9 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) DUF605 PF04652.11 AEO53283.1 - 1.5 8.1 13.1 0.062 12.6 5.3 1.5 2 0 0 2 2 2 0 Vta1 like API5 PF05918.6 AEO53283.1 - 6.7 5.0 4.9 12 4.2 3.4 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) AT_hook PF02178.14 AEO53284.1 - 8.1e-05 21.8 11.9 0.056 13.1 0.3 4.4 3 0 0 3 3 3 3 AT hook motif DUF155 PF02582.9 AEO53285.1 - 1.5e-59 200.8 0.0 2.2e-59 200.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 LBP_BPI_CETP_C PF02886.12 AEO53285.1 - 0.067 12.4 0.1 0.1 11.7 0.1 1.2 1 0 0 1 1 1 0 LBP / BPI / CETP family, C-terminal domain DNA_RNApol_7kD PF03604.8 AEO53286.1 - 0.81 9.2 7.2 2.6 7.5 0.0 2.4 2 1 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit RNase_P_p30 PF01876.11 AEO53287.1 - 3e-39 133.6 0.0 4.8e-39 132.9 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit p30 DUF2201_N PF13203.1 AEO53287.1 - 1.7 7.7 5.5 1.9 7.5 3.2 1.7 2 0 0 2 2 2 0 Putative metallopeptidase domain SSP160 PF06933.6 AEO53287.1 - 3.8 5.3 15.7 5.4 4.8 10.9 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 U79_P34 PF03064.11 AEO53287.1 - 4.6 6.6 13.3 7.9 5.9 9.3 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 CytochromB561_N PF09786.4 AEO53287.1 - 4.8 5.5 8.9 7.1 4.9 6.1 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal MOZART2 PF12926.2 AEO53288.1 - 0.75 9.4 6.9 16 5.1 0.3 3.5 2 2 1 3 3 3 0 Mitotic-spindle organizing gamma-tubulin ring associated VBS PF08913.5 AEO53288.1 - 1.1 9.4 4.4 9.5 6.4 3.0 2.3 1 1 0 1 1 1 0 Vinculin Binding Site GFA PF04828.9 AEO53289.1 - 6.5e-15 54.8 2.0 9.2e-15 54.3 1.4 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Cys_rich_CWC PF14375.1 AEO53289.1 - 2.1 8.3 8.7 0.21 11.5 2.3 2.0 2 0 0 2 2 2 0 Cysteine-rich CWC Acyl_transf_3 PF01757.17 AEO53290.1 - 2e-32 112.4 14.7 4.2e-32 111.3 10.2 1.6 1 1 0 1 1 1 1 Acyltransferase family Med8 PF10232.4 AEO53291.1 - 4.8e-26 91.6 16.9 1.3e-24 86.9 11.7 2.3 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 REC114-like PF15165.1 AEO53291.1 - 0.017 14.8 0.3 0.029 14.1 0.2 1.3 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like Myc_N PF01056.13 AEO53291.1 - 0.024 13.8 2.0 0.033 13.3 1.4 1.5 1 0 0 1 1 1 0 Myc amino-terminal region BTV_NS2 PF04514.7 AEO53291.1 - 0.042 12.7 3.3 0.056 12.3 2.3 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Sporozoite_P67 PF05642.6 AEO53291.1 - 0.061 11.1 1.4 0.082 10.7 1.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Paf1 PF03985.8 AEO53291.1 - 0.092 11.4 4.2 0.13 10.9 2.9 1.1 1 0 0 1 1 1 0 Paf1 DUF2890 PF11081.3 AEO53291.1 - 0.44 10.5 6.3 0.76 9.8 4.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Nop14 PF04147.7 AEO53291.1 - 0.56 8.0 8.1 0.82 7.5 5.6 1.2 1 0 0 1 1 1 0 Nop14-like family Retinal PF15449.1 AEO53291.1 - 0.66 7.5 5.1 0.28 8.8 0.8 1.8 2 0 0 2 2 2 0 Retinal protein DUF972 PF06156.8 AEO53291.1 - 1.1 9.6 8.6 0.29 11.5 2.3 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF972) Nucleoplasmin PF03066.10 AEO53291.1 - 1.1 8.7 13.5 0.063 12.7 5.3 1.9 3 0 0 3 3 3 0 Nucleoplasmin EBV-NA3 PF05009.7 AEO53291.1 - 2.1 7.5 4.4 4 6.6 3.0 1.4 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) DNA_pol_phi PF04931.8 AEO53291.1 - 2.5 5.7 9.2 3.7 5.1 6.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi VID27 PF08553.5 AEO53291.1 - 4.5 5.3 7.6 6.3 4.8 5.3 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein FlxA PF14282.1 AEO53291.1 - 7.8 6.4 9.9 0.51 10.3 0.3 2.3 2 0 0 2 2 2 0 FlxA-like protein Sulfatase PF00884.18 AEO53292.1 - 8.3e-54 182.8 0.0 1.2e-53 182.3 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.3 AEO53292.1 - 2.8e-24 84.7 2.6 3.8e-24 84.2 0.6 2.2 1 1 1 2 2 2 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.17 AEO53292.1 - 4.4e-10 39.4 0.2 3.1e-09 36.6 0.1 2.0 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Tox-HDC PF15656.1 AEO53292.1 - 0.039 14.1 0.0 0.084 13.0 0.0 1.6 1 0 0 1 1 1 0 Toxin with a H, D/N and C signature Metalloenzyme PF01676.13 AEO53292.1 - 0.056 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Metalloenzyme superfamily DUF229 PF02995.12 AEO53292.1 - 0.08 11.3 0.0 0.11 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) MIP-T3 PF10243.4 AEO53293.1 - 0.001 17.6 27.5 0.0012 17.4 19.1 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 SprA-related PF12118.3 AEO53293.1 - 0.003 16.9 17.3 0.0036 16.6 12.0 1.3 1 0 0 1 1 1 1 SprA-related family CAF-1_p150 PF11600.3 AEO53293.1 - 0.0052 16.1 32.1 0.0061 15.9 22.2 1.1 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Utp14 PF04615.8 AEO53293.1 - 0.0071 14.5 24.4 0.0078 14.4 16.9 1.1 1 0 0 1 1 1 1 Utp14 protein Drc1-Sld2 PF11719.3 AEO53293.1 - 0.015 14.4 19.8 0.019 14.1 13.7 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein CPSF100_C PF13299.1 AEO53293.1 - 0.016 15.4 8.8 0.018 15.2 6.1 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Daxx PF03344.10 AEO53293.1 - 0.042 12.3 17.6 0.044 12.2 12.2 1.1 1 0 0 1 1 1 0 Daxx Family U79_P34 PF03064.11 AEO53293.1 - 0.07 12.6 24.6 0.1 12.0 17.0 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF4045 PF13254.1 AEO53293.1 - 0.074 12.3 13.7 0.08 12.2 9.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Gti1_Pac2 PF09729.4 AEO53293.1 - 0.087 12.6 10.4 0.14 12.0 7.2 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family FCP1_C PF09309.5 AEO53293.1 - 0.11 11.7 14.7 0.17 11.1 10.2 1.4 1 0 0 1 1 1 0 FCP1, C-terminal DUF2413 PF10310.4 AEO53293.1 - 0.12 11.1 18.3 0.13 11.0 12.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) RR_TM4-6 PF06459.7 AEO53293.1 - 0.13 12.0 19.3 0.18 11.6 13.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Nitro_FeMo-Co PF02579.12 AEO53293.1 - 0.19 11.8 0.2 0.19 11.8 0.1 2.3 1 1 1 2 2 1 0 Dinitrogenase iron-molybdenum cofactor DUF2201_N PF13203.1 AEO53293.1 - 0.2 10.8 11.7 0.2 10.7 8.1 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain TraH PF06122.6 AEO53293.1 - 0.25 10.1 6.8 0.34 9.6 4.7 1.1 1 0 0 1 1 1 0 Conjugative relaxosome accessory transposon protein Band_3_cyto PF07565.8 AEO53293.1 - 0.34 10.3 7.6 0.37 10.2 5.2 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Raftlin PF15250.1 AEO53293.1 - 0.36 9.3 11.9 0.38 9.2 8.2 1.1 1 0 0 1 1 1 0 Raftlin DUF4557 PF15101.1 AEO53293.1 - 0.37 10.6 10.8 0.51 10.1 7.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) FAM60A PF15396.1 AEO53293.1 - 0.37 10.5 11.9 0.48 10.1 8.3 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DDHD PF02862.12 AEO53293.1 - 0.39 10.4 13.5 0.46 10.2 9.3 1.2 1 0 0 1 1 1 0 DDHD domain GAGA_bind PF06217.7 AEO53293.1 - 0.45 10.4 14.7 0.53 10.2 10.2 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family CKAP2_C PF15297.1 AEO53293.1 - 0.45 9.2 19.6 0.55 8.9 13.6 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus DDRGK PF09756.4 AEO53293.1 - 0.47 9.8 28.6 0.65 9.3 19.8 1.2 1 0 0 1 1 1 0 DDRGK domain TFIIF_alpha PF05793.7 AEO53293.1 - 0.52 8.6 27.4 0.61 8.3 19.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) HSP70 PF00012.15 AEO53293.1 - 0.55 8.0 18.8 0.77 7.5 13.0 1.1 1 0 0 1 1 1 0 Hsp70 protein SET PF00856.23 AEO53293.1 - 0.56 10.4 3.4 0.66 10.2 2.3 1.1 1 0 0 1 1 1 0 SET domain DHHW PF14286.1 AEO53293.1 - 0.58 9.4 13.2 0.73 9.0 9.2 1.1 1 0 0 1 1 1 0 DHHW protein SR-25 PF10500.4 AEO53293.1 - 0.59 9.5 23.9 1 8.7 16.5 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4407 PF14362.1 AEO53293.1 - 0.6 9.0 9.2 0.71 8.7 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CDC27 PF09507.5 AEO53293.1 - 0.62 9.2 27.3 0.69 9.0 18.9 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Tim54 PF11711.3 AEO53293.1 - 0.64 8.5 15.5 0.83 8.1 10.7 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FLO_LFY PF01698.11 AEO53293.1 - 0.97 8.2 16.1 1.2 7.9 11.2 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF913 PF06025.7 AEO53293.1 - 1 8.0 7.0 1.1 7.8 4.8 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Ycf1 PF05758.7 AEO53293.1 - 1.2 6.8 21.1 1.4 6.5 14.6 1.0 1 0 0 1 1 1 0 Ycf1 Hid1 PF12722.2 AEO53293.1 - 1.2 6.7 13.5 1.3 6.6 9.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3807 PF12720.2 AEO53293.1 - 1.2 9.2 22.9 1.9 8.5 15.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) CT47 PF15623.1 AEO53293.1 - 1.2 8.7 20.7 1.6 8.3 14.4 1.2 1 0 0 1 1 1 0 Cancer/testis gene family 47 Tom37_C PF11801.3 AEO53293.1 - 1.2 8.9 13.6 1.9 8.3 9.4 1.3 1 0 0 1 1 1 0 Tom37 C-terminal domain Paramyxo_ncap PF00973.14 AEO53293.1 - 1.4 7.5 12.1 1.6 7.3 8.4 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein RP-C_C PF11800.3 AEO53293.1 - 1.4 8.5 10.0 1.9 8.1 6.9 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region BSMAP PF12280.3 AEO53293.1 - 1.5 8.6 9.1 1.8 8.3 6.3 1.2 1 0 0 1 1 1 0 Brain specific membrane anchored protein SAPS PF04499.10 AEO53293.1 - 1.7 7.1 14.0 1.8 7.1 9.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein YqfQ PF14181.1 AEO53293.1 - 1.8 8.5 25.0 3 7.8 17.3 1.4 1 0 0 1 1 1 0 YqfQ-like protein CDC45 PF02724.9 AEO53293.1 - 1.8 6.4 19.9 2.1 6.2 13.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Paf1 PF03985.8 AEO53293.1 - 1.9 7.1 24.3 2.2 6.9 16.8 1.1 1 0 0 1 1 1 0 Paf1 Borrelia_P83 PF05262.6 AEO53293.1 - 1.9 6.6 22.7 2 6.6 15.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein OATP PF03137.15 AEO53293.1 - 2.2 6.2 4.9 2.8 5.8 3.4 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF3513 PF12026.3 AEO53293.1 - 2.4 7.6 17.9 3.4 7.1 12.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) FancD2 PF14631.1 AEO53293.1 - 2.7 4.9 10.1 2.9 4.8 7.0 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease SID-1_RNA_chan PF13965.1 AEO53293.1 - 3 5.9 8.6 3.6 5.6 5.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 FAM91_C PF14648.1 AEO53293.1 - 3.2 6.4 6.0 3.5 6.3 4.2 1.1 1 0 0 1 1 1 0 FAM91 C-terminus Afi1 PF07792.7 AEO53293.1 - 3.3 7.7 16.8 5.4 7.0 11.7 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking NARP1 PF12569.3 AEO53293.1 - 3.3 6.3 26.5 4.3 5.9 18.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 EIIBC-GUT_N PF03612.9 AEO53293.1 - 3.7 7.1 10.3 6.2 6.3 7.1 1.5 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus SGT1 PF07093.6 AEO53293.1 - 3.8 5.7 19.2 4.3 5.5 13.3 1.0 1 0 0 1 1 1 0 SGT1 protein Cellulose_synt PF03552.9 AEO53293.1 - 4.7 5.3 10.8 5.6 5.1 7.5 1.1 1 0 0 1 1 1 0 Cellulose synthase Peptidase_U57 PF05582.7 AEO53293.1 - 5.1 5.9 10.4 5.9 5.7 7.2 1.2 1 0 0 1 1 1 0 YabG peptidase U57 Sec62 PF03839.11 AEO53293.1 - 5.2 6.4 22.5 7.6 5.8 15.6 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 GBP_C PF02841.9 AEO53293.1 - 6.3 5.8 26.1 8.3 5.4 18.1 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Kei1 PF08552.6 AEO53293.1 - 6.9 6.2 5.7 11 5.6 4.0 1.5 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Presenilin PF01080.12 AEO53293.1 - 7 5.3 7.6 7.5 5.2 5.2 1.1 1 0 0 1 1 1 0 Presenilin Herpes_DNAp_acc PF04929.7 AEO53293.1 - 7.4 5.4 14.6 8.1 5.3 10.1 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Spore_coat_CotO PF14153.1 AEO53293.1 - 8.3 5.8 27.2 14 5.0 18.9 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Atrophin-1 PF03154.10 AEO53293.1 - 9.6 4.1 16.9 16 3.4 11.7 1.4 1 0 0 1 1 1 0 Atrophin-1 family PQ-loop PF04193.9 AEO53294.1 - 7.2e-25 86.3 3.7 5.2e-14 51.5 1.1 2.5 2 0 0 2 2 2 2 PQ loop repeat AT_hook PF02178.14 AEO53295.1 - 0.0014 18.0 9.4 3.6 7.5 0.1 4.0 3 0 0 3 3 3 3 AT hook motif Med3 PF11593.3 AEO53295.1 - 1.6 7.8 17.1 1.9 7.6 11.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ric8 PF10165.4 AEO53296.1 - 3.3e-130 434.9 0.1 3.8e-130 434.7 0.1 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Rif1_N PF12231.3 AEO53297.1 - 4.1e-145 483.4 2.1 6.1e-145 482.8 1.5 1.3 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Imm16 PF15565.1 AEO53297.1 - 0.89 9.4 2.8 2.8 7.8 0.0 3.0 3 0 0 3 3 3 0 Immunity protein 16 Aldose_epim PF01263.15 AEO53298.1 - 1.4e-32 113.0 0.0 1.6e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase DAHP_synth_2 PF01474.11 AEO53299.1 - 1.2e-190 633.5 0.0 1.4e-190 633.3 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family DUF3035 PF11233.3 AEO53300.1 - 0.03 14.3 0.6 0.03 14.3 0.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3035) UBA_4 PF14555.1 AEO53300.1 - 0.079 12.5 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain E1-E2_ATPase PF00122.15 AEO53301.1 - 2.4e-55 187.1 0.0 4.7e-55 186.1 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 AEO53301.1 - 3e-47 161.8 3.5 8.1e-47 160.3 2.4 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 AEO53301.1 - 7.5e-44 147.7 0.0 1e-10 41.5 0.0 4.4 4 0 0 4 4 4 4 Heavy-metal-associated domain HAD PF12710.2 AEO53301.1 - 2.8e-13 50.4 0.0 7.2e-13 49.1 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 AEO53301.1 - 6e-05 22.7 1.4 0.00014 21.5 0.5 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3133 PF11331.3 AEO53301.1 - 0.035 13.6 1.3 12 5.5 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3133) PCI PF01399.22 AEO53302.1 - 1.2e-06 28.7 0.0 2.7e-06 27.6 0.0 1.6 1 1 0 1 1 1 1 PCI domain RGS PF00615.14 AEO53303.1 - 2.8e-11 43.5 0.0 2.3e-08 34.1 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain UQ_con PF00179.21 AEO53304.1 - 1.8e-48 163.5 0.0 2.1e-48 163.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AEO53304.1 - 1.6e-05 24.6 0.0 2.3e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 AEO53304.1 - 0.0011 18.8 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 AEO53304.1 - 0.0057 16.3 0.1 0.008 15.8 0.1 1.4 1 1 0 1 1 1 1 UEV domain Pkinase PF00069.20 AEO53305.1 - 1.8e-59 201.0 0.0 2.3e-59 200.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO53305.1 - 2.1e-27 95.8 0.0 3e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO53305.1 - 1.3e-07 30.8 0.0 1.8e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AEO53305.1 - 0.004 16.9 0.2 0.26 11.0 0.0 3.1 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 AEO53305.1 - 0.0061 15.6 0.0 0.028 13.4 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family SprT-like PF10263.4 AEO53306.1 - 9.6e-15 54.5 0.0 1.9e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 SprT-like family TraY PF05509.6 AEO53306.1 - 0.69 9.7 3.5 0.24 11.1 0.5 1.8 2 0 0 2 2 2 0 TraY domain F-box-like PF12937.2 AEO53307.1 - 8e-12 44.7 0.0 1.7e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 AEO53307.1 - 6.3e-09 35.2 0.0 1.7e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 F-box domain Herpes_US9 PF06072.6 AEO53308.1 - 0.085 12.7 3.5 3.2 7.6 0.8 2.6 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 ABC_tran PF00005.22 AEO53309.1 - 5.6e-50 169.1 0.0 2.5e-29 102.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 AEO53309.1 - 1.9e-30 106.2 21.7 1.4e-18 67.2 4.8 3.6 4 0 0 4 4 4 2 ABC transporter transmembrane region SMC_N PF02463.14 AEO53309.1 - 6.4e-10 38.6 0.0 0.00016 20.9 0.0 4.2 3 1 1 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 AEO53309.1 - 2.6e-06 26.9 0.0 0.0074 15.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 AEO53309.1 - 0.00024 20.0 0.0 0.23 10.3 0.0 2.2 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.1 AEO53309.1 - 0.00028 20.9 0.7 0.069 13.1 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 AEO53309.1 - 0.00039 19.8 0.6 0.61 9.6 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 AEO53309.1 - 0.00062 20.1 0.0 0.04 14.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 AEO53309.1 - 0.0064 15.6 0.0 3.1 6.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 AEO53309.1 - 0.016 15.3 0.1 22 5.1 0.1 3.4 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.18 AEO53309.1 - 0.02 14.8 0.2 0.53 10.2 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.1 AEO53309.1 - 0.024 14.2 0.3 3.7 7.0 0.0 2.8 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.12 AEO53309.1 - 0.032 14.0 2.0 1 9.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 SbcCD_C PF13558.1 AEO53309.1 - 0.045 13.6 0.0 4.7 7.1 0.0 3.0 3 0 0 3 3 2 0 Putative exonuclease SbcCD, C subunit IstB_IS21 PF01695.12 AEO53309.1 - 0.046 13.1 0.0 5 6.4 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein Miro PF08477.8 AEO53309.1 - 0.074 13.5 1.8 6.1 7.3 0.0 2.9 2 1 0 2 2 2 0 Miro-like protein DUF2075 PF09848.4 AEO53309.1 - 0.13 11.2 0.1 1.5 7.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.2 AEO53309.1 - 0.17 11.3 0.4 4 6.7 0.0 2.4 2 1 0 2 2 2 0 AAA-like domain AAA_21 PF13304.1 AEO53309.1 - 0.2 11.5 7.9 4.2 7.2 0.0 4.1 5 0 0 5 5 4 0 AAA domain WD40 PF00400.27 AEO53310.1 - 4e-27 93.0 11.0 8.5e-08 31.7 0.0 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 AEO53310.1 - 0.00031 20.5 0.2 0.33 10.6 0.0 3.1 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A HIRA_B PF09453.5 AEO53310.1 - 0.0049 16.3 0.8 0.0049 16.3 0.6 2.4 2 0 0 2 2 2 1 HIRA B motif Amidase PF01425.16 AEO53311.1 - 3.4e-82 276.6 0.0 4.1e-82 276.3 0.0 1.1 1 0 0 1 1 1 1 Amidase DUF1776 PF08643.5 AEO53313.1 - 5.4e-115 383.6 0.0 6.7e-115 383.3 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) zf-CCCH PF00642.19 AEO53314.1 - 6.9e-17 60.7 34.5 7.6e-07 28.6 0.2 5.3 4 1 1 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 AEO53314.1 - 0.021 14.8 0.2 0.021 14.8 0.2 5.6 6 0 0 6 6 6 0 Zinc finger C-x8-C-x5-C-x3-H type Trypan_PARP PF05887.6 AEO53314.1 - 2.4 7.9 11.7 4 7.2 8.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MIP-T3 PF10243.4 AEO53314.1 - 2.9 6.2 21.2 3.8 5.8 14.7 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1777 PF08648.7 AEO53314.1 - 4.3 7.0 24.8 5.9 6.5 17.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Atrophin-1 PF03154.10 AEO53314.1 - 7.4 4.5 28.1 12 3.8 19.4 1.3 1 0 0 1 1 1 0 Atrophin-1 family ADH_zinc_N PF00107.21 AEO53315.1 - 8.6e-35 119.1 2.9 1.3e-34 118.5 0.9 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.9 AEO53315.1 - 8.4e-29 100.8 1.3 1.3e-28 100.3 0.3 1.9 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AEO53315.1 - 1.5e-18 66.9 3.3 9.5e-17 61.1 0.7 3.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AEO53315.1 - 7.7e-14 52.2 0.3 6.2e-09 36.2 0.0 3.6 2 2 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N_2 PF13602.1 AEO53315.1 - 1e-11 45.8 0.1 5.4e-11 43.4 0.1 2.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AEO53315.1 - 1.3e-06 28.0 0.0 5.5e-06 26.1 0.0 2.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_7 PF13241.1 AEO53315.1 - 1.8e-05 24.9 1.5 0.0018 18.4 0.0 3.1 3 1 0 3 3 3 1 Putative NAD(P)-binding Thi4 PF01946.12 AEO53315.1 - 6.9e-05 22.0 0.0 0.00071 18.7 0.0 2.5 3 0 0 3 3 3 1 Thi4 family K_oxygenase PF13434.1 AEO53315.1 - 0.0002 20.4 0.3 0.071 12.0 0.0 3.2 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 AEO53315.1 - 0.00022 20.2 3.8 1 8.1 0.1 4.0 3 2 0 4 4 4 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AEO53315.1 - 0.00028 20.8 1.0 0.15 12.1 0.0 3.1 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.16 AEO53315.1 - 0.00072 19.1 5.1 0.25 10.8 0.9 4.0 4 0 0 4 4 4 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.15 AEO53315.1 - 0.0019 18.2 2.1 2 8.5 0.1 3.2 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 AEO53315.1 - 0.011 14.8 0.7 10 5.0 0.0 3.2 2 1 1 3 3 3 0 FAD binding domain GIDA PF01134.17 AEO53315.1 - 0.029 13.2 3.0 1 8.1 0.3 3.3 2 2 1 3 3 3 0 Glucose inhibited division protein A FAD_binding_2 PF00890.19 AEO53315.1 - 0.035 12.9 4.7 0.17 10.6 0.2 3.1 2 2 2 4 4 4 0 FAD binding domain TrkA_N PF02254.13 AEO53315.1 - 0.046 13.7 2.3 0.2 11.6 0.1 3.0 4 0 0 4 4 3 0 TrkA-N domain 2-Hacid_dh_C PF02826.14 AEO53315.1 - 0.34 10.0 2.5 1.6 7.8 0.1 2.7 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain LRS4 PF10422.4 AEO53316.1 - 0.057 12.7 0.1 0.061 12.6 0.1 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 RVT_1 PF00078.22 AEO53317.1 - 0.0028 17.0 0.2 0.0029 16.9 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3786 PF12654.2 AEO53317.1 - 0.018 14.3 0.3 0.023 13.9 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3786) RVT_1 PF00078.22 AEO53318.1 - 0.00031 20.1 0.7 0.00033 20.0 0.5 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3786 PF12654.2 AEO53318.1 - 0.036 13.3 0.5 0.046 12.9 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3786) DUF1772 PF08592.6 AEO53320.1 - 2.7e-21 75.7 8.2 1.3e-20 73.5 5.7 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) PEP_mutase PF13714.1 AEO53320.1 - 0.59 9.2 4.2 0.46 9.6 0.8 1.9 1 1 1 2 2 2 0 Phosphoenolpyruvate phosphomutase Pex2_Pex12 PF04757.9 AEO53321.1 - 8.1e-42 143.1 0.7 1.6e-41 142.1 0.0 1.7 2 0 0 2 2 2 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.1 AEO53321.1 - 0.00093 19.0 4.0 0.0018 18.0 2.7 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Ferric_reduct PF01794.14 AEO53321.1 - 0.012 15.7 1.4 0.021 14.9 1.0 1.3 1 0 0 1 1 1 0 Ferric reductase like transmembrane component zf-C3HC4 PF00097.20 AEO53321.1 - 0.062 12.9 1.2 0.13 11.9 0.8 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 AEO53321.1 - 0.14 11.8 1.8 0.15 11.7 0.2 1.8 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_2 PF13923.1 AEO53321.1 - 0.51 10.4 8.6 0.18 11.8 3.0 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FAD_binding_8 PF08022.7 AEO53322.1 - 2.9e-23 81.7 0.0 5.8e-23 80.7 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 AEO53322.1 - 9.2e-23 80.8 0.0 1.6e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 AEO53322.1 - 6.2e-17 61.8 9.8 6.2e-17 61.8 6.8 2.0 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 AEO53322.1 - 8e-05 22.6 0.0 0.00025 21.1 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain LrgA PF03788.9 AEO53322.1 - 0.019 14.6 1.1 0.033 13.8 0.1 1.8 2 0 0 2 2 2 0 LrgA family NAD_binding_1 PF00175.16 AEO53322.1 - 0.14 12.6 0.0 3.3 8.3 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Myosin_head PF00063.16 AEO53323.1 - 3.6e-232 772.2 1.8 6.9e-232 771.3 1.3 1.4 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 AEO53323.1 - 5.4e-41 140.1 0.0 1.5e-40 138.6 0.0 1.8 2 0 0 2 2 2 1 Myosin tail SH3_1 PF00018.23 AEO53323.1 - 2.3e-06 26.8 0.0 4.7e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 AEO53323.1 - 0.00079 18.9 0.0 0.002 17.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain IQ PF00612.22 AEO53323.1 - 0.001 18.5 10.3 0.035 13.7 1.6 2.7 1 1 1 2 2 2 2 IQ calmodulin-binding motif SH3_2 PF07653.12 AEO53323.1 - 0.0035 16.7 0.0 0.02 14.3 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain AAA_22 PF13401.1 AEO53323.1 - 0.0056 16.8 0.0 0.015 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 AEO53323.1 - 0.019 14.0 0.0 0.044 12.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Hpr_kinase_C PF07475.7 AEO53323.1 - 0.02 14.2 0.2 3.2 7.0 0.0 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain NACHT PF05729.7 AEO53323.1 - 0.048 13.3 0.2 0.22 11.1 0.0 2.2 3 0 0 3 3 3 0 NACHT domain AAA_17 PF13207.1 AEO53323.1 - 0.064 14.0 0.0 0.2 12.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 AEO53323.1 - 0.14 12.4 0.0 0.32 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain GP38 PF05268.6 AEO53324.1 - 3.5 6.9 13.8 4.3 6.6 9.6 1.1 1 0 0 1 1 1 0 Phage tail fibre adhesin Gp38 zf-DHHC PF01529.15 AEO53325.1 - 1.1e-31 109.5 0.0 1.6e-31 109.0 0.0 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase Acyl_transf_3 PF01757.17 AEO53325.1 - 0.00057 18.8 0.3 0.00091 18.1 0.2 1.3 1 0 0 1 1 1 1 Acyltransferase family DZR PF12773.2 AEO53325.1 - 0.1 12.4 7.5 0.19 11.5 5.2 1.3 1 0 0 1 1 1 0 Double zinc ribbon Glyco_transf_90 PF05686.7 AEO53326.1 - 1.5e-08 33.7 1.9 0.014 14.1 0.4 3.6 3 1 0 3 3 3 2 Glycosyl transferase family 90 Glyco_hydro_18 PF00704.23 AEO53327.1 - 6.8e-67 226.3 0.0 8e-67 226.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3115 PF11312.3 AEO53327.1 - 0.11 11.2 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3115) ubiquitin PF00240.18 AEO53329.1 - 7.3e-19 66.9 0.1 1.1e-18 66.3 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 AEO53329.1 - 2.5e-09 36.6 0.2 1e-08 34.7 0.0 2.2 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD PF11976.3 AEO53329.1 - 3.3e-05 23.5 0.4 4.9e-05 22.9 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 AEO53329.1 - 0.0014 18.5 0.0 0.0024 17.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 AEO53329.1 - 0.0035 17.5 0.0 0.0064 16.6 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_2 PF14560.1 AEO53329.1 - 0.2 11.9 0.9 0.93 9.7 0.7 1.9 1 1 0 1 1 1 0 Ubiquitin-like domain Mpv17_PMP22 PF04117.7 AEO53330.1 - 3.8e-26 90.5 1.1 4.4e-26 90.3 0.4 1.4 2 0 0 2 2 2 1 Mpv17 / PMP22 family UDPGP PF01704.13 AEO53331.1 - 4.8e-53 180.1 0.0 6.7e-53 179.6 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 AEO53331.1 - 0.072 13.1 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 MobA-like NTP transferase domain UDG PF03167.14 AEO53332.1 - 9.1e-24 83.6 0.1 2.2e-23 82.3 0.0 1.7 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily Pap_E4 PF02711.9 AEO53332.1 - 3.6 8.4 7.4 5.8 7.8 4.5 1.8 2 0 0 2 2 2 0 E4 protein BSP_II PF05432.6 AEO53332.1 - 5.3 6.2 13.8 3 7.0 3.1 2.2 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Med3 PF11593.3 AEO53332.1 - 5.6 6.1 11.1 7.6 5.6 7.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal FoP_duplication PF13865.1 AEO53333.1 - 2.7 8.5 9.5 5.9 7.4 6.6 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 DUF3628 PF12300.3 AEO53333.1 - 9.1 6.2 15.5 20 5.1 10.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3628) zf-C3HC4_2 PF13923.1 AEO53334.1 - 2.2 8.3 5.8 3.6 7.6 4.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) LMBR1 PF04791.11 AEO53335.1 - 1.2e-14 53.8 3.3 1.2e-14 53.8 2.3 2.2 1 1 1 2 2 2 1 LMBR1-like membrane protein GRP PF07172.6 AEO53335.1 - 0.014 15.8 0.9 0.014 15.8 0.7 2.8 3 0 0 3 3 3 0 Glycine rich protein family DUF1980 PF09323.5 AEO53335.1 - 1.1 9.0 3.0 11 5.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) CPSF_A PF03178.10 AEO53336.1 - 5.7e-78 262.2 0.0 1.6e-77 260.7 0.0 1.8 1 1 0 1 1 1 1 CPSF A subunit region SR-25 PF10500.4 AEO53336.1 - 0.0039 16.6 3.2 0.0039 16.6 2.3 2.2 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Pol_alpha_B_N PF08418.5 AEO53336.1 - 3.2 7.2 11.4 5.4 6.4 7.9 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Nucleoplasmin PF03066.10 AEO53336.1 - 5.9 6.3 7.4 13 5.2 5.2 1.5 1 0 0 1 1 1 0 Nucleoplasmin Pal1 PF08316.6 AEO53337.1 - 4.8e-10 40.0 0.0 9.3e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Pal1 cell morphology protein HVSL PF09749.4 AEO53338.1 - 2.9e-61 206.5 0.0 6.1e-37 126.9 0.0 1.9 2 0 0 2 2 2 2 Uncharacterised conserved protein Telomere_Sde2 PF13019.1 AEO53338.1 - 0.1 12.2 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Telomere stability and silencing ERO1 PF04137.10 AEO53339.1 - 7.7e-137 456.0 0.0 1.2e-136 455.4 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) CKS PF01111.14 AEO53340.1 - 1.7e-34 117.4 0.4 2.2e-34 117.0 0.3 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Bromodomain PF00439.20 AEO53341.1 - 6.7e-35 118.8 0.1 6.1e-18 64.5 0.3 2.3 2 0 0 2 2 2 2 Bromodomain RNA_pol_3_Rpc31 PF11705.3 AEO53341.1 - 0.11 12.4 7.0 0.21 11.5 4.8 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CDC45 PF02724.9 AEO53341.1 - 1.8 6.5 3.7 2.6 5.9 2.5 1.1 1 0 0 1 1 1 0 CDC45-like protein GST_C_2 PF13410.1 AEO53342.1 - 0.033 14.0 1.7 1.2 9.0 0.0 3.3 3 1 0 3 3 3 0 Glutathione S-transferase, C-terminal domain WD40 PF00400.27 AEO53343.1 - 9.3e-14 50.6 5.9 4.7e-06 26.2 0.3 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat eIF2A PF08662.6 AEO53343.1 - 4.1e-06 26.6 0.0 0.015 15.0 0.0 3.3 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 AEO53343.1 - 0.04 13.3 0.1 0.29 10.5 0.1 2.3 1 1 1 2 2 2 0 PQQ-like domain Thg1C PF14413.1 AEO53344.1 - 5e-52 174.6 0.5 6.9e-52 174.2 0.4 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 AEO53344.1 - 9.3e-49 164.5 0.0 1.3e-48 164.0 0.0 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase CAF-1_p150 PF11600.3 AEO53345.1 - 3.3e-05 23.3 26.3 3.9e-05 23.1 18.2 1.2 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal TPR_3 PF07720.7 AEO53345.1 - 0.2 11.4 1.0 0.34 10.7 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat FUSC PF04632.7 AEO53345.1 - 3.8 5.8 6.7 3.7 5.8 4.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family RNA_pol_Rpb1_1 PF04997.7 AEO53346.1 - 4.9e-113 377.7 0.0 8.1e-113 377.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 AEO53346.1 - 1.2e-98 329.7 0.1 2.3e-98 328.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 AEO53346.1 - 2.3e-69 232.5 0.0 5.7e-69 231.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 AEO53346.1 - 2.3e-58 197.0 3.6 5.3e-58 195.8 2.5 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 AEO53346.1 - 6.8e-47 159.1 0.0 2.4e-46 157.3 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 AEO53346.1 - 4.4e-46 155.9 8.0 7.4e-46 155.2 5.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 AEO53346.1 - 3.8e-38 129.5 0.2 8.6e-38 128.3 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 zf-C4pol PF14260.1 AEO53346.1 - 0.23 11.4 0.7 0.53 10.3 0.5 1.6 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta F-box PF00646.28 AEO53349.1 - 0.15 11.7 0.2 0.15 11.7 0.1 1.7 2 0 0 2 2 2 0 F-box domain HSP70 PF00012.15 AEO53350.1 - 8.3e-237 786.8 7.4 9.3e-237 786.7 5.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 AEO53350.1 - 2.2e-17 62.6 0.2 2e-16 59.4 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 AEO53350.1 - 0.0023 17.6 0.0 0.0045 16.6 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 AEO53350.1 - 0.059 13.2 2.2 14 5.5 0.1 3.9 3 1 0 3 3 3 0 Cell division protein FtsA Activator_LAG-3 PF11498.3 AEO53350.1 - 0.18 10.5 0.0 0.33 9.6 0.0 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 IF4E PF01652.13 AEO53351.1 - 4.2e-61 205.2 0.1 5.2e-61 204.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E AMP-binding PF00501.23 AEO53352.1 - 4.1e-73 246.1 0.0 6.6e-73 245.4 0.0 1.3 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 AEO53352.1 - 7.2e-11 42.8 0.1 1.5e-10 41.8 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain BolA PF01722.13 AEO53353.1 - 9.8e-29 99.1 0.2 1.2e-28 98.9 0.1 1.1 1 0 0 1 1 1 1 BolA-like protein vMSA PF00695.14 AEO53354.1 - 0.89 8.6 3.7 1.8 7.6 2.6 1.5 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus PIP5K PF01504.13 AEO53355.1 - 1.9e-58 197.5 0.2 3.5e-58 196.6 0.2 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 AEO53355.1 - 5.7e-25 87.8 0.0 8.8e-25 87.2 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 AEO53355.1 - 5.5e-13 48.6 12.1 5.5e-13 48.6 8.4 2.1 2 0 0 2 2 2 1 FYVE zinc finger FF PF01846.14 AEO53355.1 - 0.012 15.5 0.1 0.9 9.5 0.0 2.7 2 0 0 2 2 2 0 FF domain FYVE_2 PF02318.11 AEO53355.1 - 4.5 7.2 11.7 0.49 10.2 4.2 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger Sporozoite_P67 PF05642.6 AEO53356.1 - 2.2 6.0 2.0 4.4 5.0 1.4 1.5 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Cyclin_N PF00134.18 AEO53358.1 - 5.3e-39 132.6 0.6 1.7e-38 131.0 0.1 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 AEO53358.1 - 2.6e-11 43.4 0.3 9.7e-11 41.6 0.2 2.0 1 1 0 1 1 1 1 Cyclin, C-terminal domain Scytalone_dh PF02982.9 AEO53360.1 - 7.2e-90 298.6 0.8 8.2e-90 298.5 0.6 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 AEO53360.1 - 4.9e-07 29.7 0.4 6.4e-07 29.3 0.3 1.2 1 0 0 1 1 1 1 SnoaL-like domain Rad4 PF03835.10 AEO53361.1 - 1.7e-14 53.4 7.3 3.1e-14 52.5 5.0 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.14 AEO53361.1 - 2.2e-14 53.6 2.4 6.9e-14 52.0 1.6 1.9 1 0 0 1 1 1 1 Transglutaminase-like superfamily WD40 PF00400.27 AEO53362.1 - 3.5e-08 33.0 19.6 0.0025 17.6 0.0 9.6 12 0 0 12 12 12 2 WD domain, G-beta repeat PQQ_2 PF13360.1 AEO53362.1 - 2.7e-07 30.2 0.3 8.3e-07 28.7 0.2 1.8 2 0 0 2 2 2 1 PQQ-like domain PQQ PF01011.16 AEO53362.1 - 0.013 14.9 0.1 0.55 9.8 0.0 2.8 2 0 0 2 2 2 0 PQQ enzyme repeat PQQ_3 PF13570.1 AEO53362.1 - 0.017 15.3 0.2 23 5.4 0.0 4.2 4 0 0 4 4 4 0 PQQ-like domain VID27 PF08553.5 AEO53362.1 - 3.4 5.7 4.1 0.63 8.1 0.0 1.7 2 0 0 2 2 2 0 VID27 cytoplasmic protein NAPRTase PF04095.11 AEO53363.1 - 9.5e-53 178.9 0.3 5.5e-52 176.4 0.2 1.9 1 1 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family Methyltransf_23 PF13489.1 AEO53364.1 - 7.7e-16 58.2 0.0 1.1e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO53364.1 - 2.1e-09 37.9 0.1 2.3e-08 34.6 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO53364.1 - 1.1e-08 34.7 0.0 6.1e-08 32.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO53364.1 - 5.6e-07 29.9 0.0 1.2e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO53364.1 - 1.7e-06 28.4 0.0 4.1e-06 27.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO53364.1 - 0.00049 20.4 0.0 0.0016 18.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AEO53364.1 - 0.00053 19.4 0.0 0.00095 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 AEO53364.1 - 0.0024 17.8 0.0 0.0032 17.4 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 AEO53364.1 - 0.003 17.0 0.0 0.0048 16.3 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase ketoacyl-synt PF00109.21 AEO53364.1 - 0.0062 16.0 0.0 0.013 15.0 0.0 1.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Methyltransf_4 PF02390.12 AEO53364.1 - 0.011 14.7 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_26 PF13659.1 AEO53364.1 - 0.045 13.7 0.0 0.15 12.0 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain ATP-synt_G PF04718.10 AEO53365.1 - 9.4e-28 96.8 0.2 7.1e-27 94.0 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit ADH_N PF08240.7 AEO53366.1 - 8.2e-27 93.1 3.4 1.8e-26 92.0 2.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AEO53366.1 - 2.6e-15 56.1 0.0 4.2e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase S1-like PF14444.1 AEO53366.1 - 0.093 12.4 0.1 4.3 7.1 0.0 2.6 2 0 0 2 2 2 0 S1-like Bap31 PF05529.7 AEO53367.1 - 9.7e-68 227.4 3.4 1.1e-67 227.2 2.3 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like Phage_GP20 PF06810.6 AEO53367.1 - 0.5 9.8 5.7 0.67 9.3 4.0 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 DivIC PF04977.10 AEO53367.1 - 0.53 9.7 6.1 0.44 10.0 0.2 3.1 4 0 0 4 4 4 0 Septum formation initiator Anoctamin PF04547.7 AEO53367.1 - 0.8 8.2 5.1 0.51 8.9 2.5 1.4 1 1 0 1 1 1 0 Calcium-activated chloride channel DUF1479 PF07350.7 AEO53368.1 - 4.1e-134 447.1 0.0 5.8e-134 446.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) NAC PF01849.13 AEO53368.1 - 0.089 12.3 0.2 0.17 11.3 0.1 1.4 1 0 0 1 1 1 0 NAC domain HHH PF00633.18 AEO53368.1 - 0.13 12.0 0.2 0.41 10.4 0.1 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix motif zf-met2 PF12907.2 AEO53369.1 - 6.9e-15 54.7 1.7 6.9e-15 54.7 1.2 1.5 2 0 0 2 2 2 1 Zinc-binding 4F5 PF04419.9 AEO53369.1 - 0.0066 17.1 9.7 0.011 16.4 6.7 1.3 1 0 0 1 1 1 1 4F5 protein family Flu_M1_C PF08289.6 AEO53369.1 - 0.078 13.0 0.2 0.1 12.6 0.2 1.1 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain 2OG-FeII_Oxy PF03171.15 AEO53370.1 - 6.5e-14 52.0 0.0 1.1e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 AEO53370.1 - 9.6e-08 32.5 0.0 3.5e-06 27.5 0.0 2.3 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal WD40 PF00400.27 AEO53371.1 - 1.1e-07 31.5 5.8 0.00068 19.4 0.0 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat DUF4597 PF15366.1 AEO53371.1 - 0.044 13.3 0.4 0.28 10.7 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4597) MRJP PF03022.11 AEO53371.1 - 0.064 12.4 0.5 0.99 8.5 0.0 2.6 3 0 0 3 3 3 0 Major royal jelly protein RNA_pol_N PF01194.12 AEO53372.1 - 8e-29 99.4 1.3 1e-28 99.0 0.9 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.7 AEO53372.1 - 0.026 14.6 0.6 0.038 14.0 0.4 1.3 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) XK-related PF09815.4 AEO53373.1 - 0.021 13.8 0.0 0.031 13.2 0.0 1.2 1 0 0 1 1 1 0 XK-related protein DUF416 PF04222.7 AEO53373.1 - 0.086 11.9 0.0 0.22 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF416) Pneumo_phosprot PF02478.11 AEO53373.1 - 3.4 7.1 6.8 0.87 9.0 2.4 1.7 1 1 0 1 1 1 0 Pneumovirus phosphoprotein Methyltransf_16 PF10294.4 AEO53374.1 - 1.8e-21 76.3 0.0 2.2e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 AEO53374.1 - 0.071 12.2 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 AEO53374.1 - 0.076 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.2 AEO53374.1 - 0.09 13.3 0.1 0.15 12.6 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase domain Dynein_light PF01221.13 AEO53377.1 - 1.9e-41 139.9 1.4 2.2e-41 139.7 1.0 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 RRM_1 PF00076.17 AEO53378.1 - 5.3e-65 214.9 4.4 7.4e-16 57.5 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO53378.1 - 4.5e-62 205.9 1.6 9.4e-14 51.1 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO53378.1 - 2.8e-30 103.9 1.4 2.1e-06 27.4 0.0 5.5 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 AEO53378.1 - 3e-05 23.7 1.4 2 8.2 0.1 4.8 4 1 0 4 4 4 2 Limkain b1 Nup35_RRM PF05172.8 AEO53378.1 - 4.3e-05 23.1 0.0 0.002 17.8 0.0 3.2 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 AEO53378.1 - 0.00024 20.8 0.0 4.1 7.2 0.0 4.3 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 AEO53378.1 - 0.0089 15.8 6.4 0.72 9.7 0.0 4.9 5 1 0 5 5 5 1 RNA binding motif TEA PF01285.13 AEO53379.1 - 0.0029 16.8 4.5 0.0029 16.8 3.1 3.2 2 1 0 2 2 2 1 TEA/ATTS domain family Zip PF02535.17 AEO53379.1 - 0.11 11.5 4.4 0.22 10.4 3.0 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Pro_isomerase PF00160.16 AEO53381.1 - 5.9e-48 162.9 0.3 6.7e-48 162.8 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thioredoxin_3 PF13192.1 AEO53381.1 - 0.14 12.0 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain Dus PF01207.12 AEO53382.1 - 7e-39 133.4 0.0 6.7e-29 100.6 0.0 2.7 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 AEO53382.1 - 0.013 15.1 4.3 1 9.1 0.3 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Kelch_4 PF13418.1 AEO53383.1 - 2.6e-44 148.7 15.5 1.6e-09 37.3 0.1 6.7 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 AEO53383.1 - 1.1e-38 130.5 35.6 1e-09 38.2 0.1 7.9 8 0 0 8 8 7 6 Galactose oxidase, central domain Kelch_5 PF13854.1 AEO53383.1 - 1e-37 127.4 26.7 3.6e-07 29.9 0.1 7.0 7 0 0 7 7 6 6 Kelch motif Kelch_1 PF01344.20 AEO53383.1 - 1.4e-37 126.9 17.6 1.6e-08 33.9 1.4 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 AEO53383.1 - 1.3e-34 116.8 17.5 1.6e-07 31.2 0.2 6.5 4 2 2 6 6 6 6 Kelch motif Kelch_2 PF07646.10 AEO53383.1 - 7.3e-31 104.7 25.0 8e-09 34.9 0.1 7.1 7 0 0 7 7 6 6 Kelch motif Nucleoplasmin PF03066.10 AEO53383.1 - 0.13 11.7 7.4 0.22 11.0 5.1 1.3 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 AEO53383.1 - 0.23 11.0 4.7 0.34 10.4 3.3 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.9 AEO53383.1 - 0.33 8.9 3.7 0.47 8.4 2.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Herpes_gE PF02480.11 AEO53383.1 - 0.43 8.7 3.3 0.67 8.1 2.3 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Nop14 PF04147.7 AEO53383.1 - 0.49 8.2 4.8 0.65 7.8 3.3 1.1 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.1 AEO53383.1 - 1.5 8.4 3.9 3.4 7.3 2.7 1.5 1 0 0 1 1 1 0 FAM176 family HIG_1_N PF04588.8 AEO53384.1 - 5.6e-07 29.2 3.2 5.6e-07 29.2 2.2 1.8 2 0 0 2 2 2 1 Hypoxia induced protein conserved region DUF4079 PF13301.1 AEO53384.1 - 0.029 14.3 0.2 0.048 13.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) WHG PF13305.1 AEO53384.1 - 0.031 14.8 0.1 0.068 13.7 0.0 1.6 1 0 0 1 1 1 0 WHG domain S1-P1_nuclease PF02265.11 AEO53384.1 - 0.11 12.1 1.3 0.17 11.5 0.9 1.2 1 0 0 1 1 1 0 S1/P1 Nuclease Romo1 PF10247.4 AEO53384.1 - 0.52 10.5 4.4 0.1 12.7 0.6 1.6 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 zf-H2C2_2 PF13465.1 AEO53385.1 - 0.0066 16.6 0.7 0.0066 16.6 0.5 3.5 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 AEO53385.1 - 0.029 14.5 0.2 0.029 14.5 0.1 4.0 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 AEO53385.1 - 0.047 14.0 0.5 0.047 14.0 0.4 4.8 5 0 0 5 5 5 0 C2H2-type zinc finger TraG_N PF07916.6 AEO53385.1 - 1.4 7.2 9.9 0.49 8.7 3.9 2.0 1 1 1 2 2 2 0 TraG-like protein, N-terminal region zf-C2H2 PF00096.21 AEO53385.1 - 1.6 9.2 22.4 0.096 13.0 1.1 4.0 4 0 0 4 4 4 0 Zinc finger, C2H2 type Kelch_4 PF13418.1 AEO53386.1 - 1.8e-26 91.6 11.3 1.3e-08 34.5 0.0 5.7 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 AEO53386.1 - 1.2e-23 82.5 6.7 6e-07 29.2 0.0 5.3 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 AEO53386.1 - 4.6e-22 77.2 2.5 0.00018 21.4 0.0 5.2 3 1 2 5 5 5 4 Kelch motif Kelch_3 PF13415.1 AEO53386.1 - 1.1e-21 76.3 3.8 3.2e-07 30.3 0.1 5.6 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.20 AEO53386.1 - 4.3e-21 74.1 0.5 5e-05 22.7 0.1 4.7 4 0 0 4 4 4 4 Kelch motif Kelch_2 PF07646.10 AEO53386.1 - 2.5e-17 61.8 3.8 0.0016 18.1 0.0 5.1 4 0 0 4 4 4 4 Kelch motif BTB PF00651.26 AEO53386.1 - 8.7e-09 35.3 0.0 1.5e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Rax2 PF12768.2 AEO53386.1 - 0.13 11.4 0.0 0.49 9.5 0.0 2.0 1 1 1 2 2 2 0 Cortical protein marker for cell polarity WD40 PF00400.27 AEO53387.1 - 3.5e-23 80.5 21.6 1.7e-06 27.7 0.1 7.5 8 0 0 8 8 8 5 WD domain, G-beta repeat eIF2A PF08662.6 AEO53387.1 - 2.7e-05 23.9 0.6 0.0011 18.7 0.2 2.4 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 AEO53387.1 - 0.032 13.7 0.0 0.33 10.4 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain TFIIA PF03153.8 AEO53388.1 - 5.4e-86 289.8 37.5 3.7e-84 283.8 26.0 2.0 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF4407 PF14362.1 AEO53388.1 - 8.8 5.1 16.6 14 4.5 11.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Peroxin-13_N PF04088.8 AEO53389.1 - 5.5e-58 195.4 0.0 7.9e-58 194.8 0.0 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 AEO53389.1 - 9.2e-09 34.6 0.0 1.4e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 AEO53389.1 - 1.2e-06 27.7 0.1 3.4e-06 26.3 0.0 1.7 1 1 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 AEO53389.1 - 9e-06 25.1 0.0 1.6e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain HSP70 PF00012.15 AEO53390.1 - 8.8e-38 129.6 0.0 9.8e-38 129.4 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein p450 PF00067.17 AEO53391.1 - 8.9e-69 232.1 0.0 1.1e-68 231.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_transf_11 PF01531.11 AEO53392.1 - 0.22 10.4 0.1 0.41 9.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 11 Kinesin PF00225.18 AEO53394.1 - 2.5e-98 328.8 0.0 4e-98 328.2 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain OmpH PF03938.9 AEO53394.1 - 1.1 9.1 5.9 0.45 10.4 0.8 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Stk19 PF10494.4 AEO53395.1 - 1.7e-41 142.2 0.0 2.3e-41 141.8 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 Sulfate_transp PF00916.15 AEO53396.1 - 9.4e-36 123.2 0.7 2e-35 122.1 0.5 1.6 1 0 0 1 1 1 1 Sulfate transporter family cNMP_binding PF00027.24 AEO53396.1 - 1.8e-14 53.3 0.0 3.3e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 AEO53396.1 - 2.3e-10 39.8 0.0 5.1e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 STAS domain Sld5 PF05916.6 AEO53397.1 - 1.8e-13 50.7 0.0 2.7e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein AAA_2 PF07724.9 AEO53398.1 - 1.3e-44 152.0 0.1 1.5e-43 148.7 0.0 2.5 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 AEO53398.1 - 4.4e-24 84.2 0.1 1.6e-23 82.3 0.1 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 AEO53398.1 - 1.5e-18 67.2 0.0 1.5e-09 38.1 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 AEO53398.1 - 3.8e-11 42.8 0.0 1.8e-08 34.2 0.0 2.8 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 AEO53398.1 - 2.2e-09 37.5 10.3 0.007 16.3 0.1 5.1 3 2 2 5 5 5 2 AAA ATPase domain AAA_22 PF13401.1 AEO53398.1 - 3.5e-08 33.6 0.3 0.014 15.5 0.0 3.3 2 2 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 AEO53398.1 - 4.8e-06 26.1 0.5 0.00047 19.6 0.0 2.6 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.1 AEO53398.1 - 5.2e-06 26.3 0.0 0.15 11.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 AEO53398.1 - 8.1e-06 25.7 7.8 0.25 11.0 0.0 4.7 3 2 0 4 4 4 2 Archaeal ATPase NACHT PF05729.7 AEO53398.1 - 3.8e-05 23.4 0.3 0.34 10.5 0.0 2.9 2 1 0 3 3 3 2 NACHT domain IstB_IS21 PF01695.12 AEO53398.1 - 0.00023 20.6 0.0 0.24 10.8 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_17 PF13207.1 AEO53398.1 - 0.00024 21.9 3.8 0.024 15.4 0.1 3.8 3 1 0 3 3 3 1 AAA domain ABC_tran PF00005.22 AEO53398.1 - 0.0011 19.2 0.5 0.27 11.5 0.0 3.4 3 0 0 3 3 3 1 ABC transporter DUF258 PF03193.11 AEO53398.1 - 0.0013 17.9 0.1 0.99 8.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MobB PF03205.9 AEO53398.1 - 0.0013 18.4 0.0 0.27 10.9 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 AEO53398.1 - 0.0027 17.5 0.1 4.4 7.1 0.0 3.1 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.17 AEO53398.1 - 0.0033 17.5 0.0 1 9.5 0.0 3.0 2 1 0 2 2 2 1 RNA helicase AAA_19 PF13245.1 AEO53398.1 - 0.0047 16.6 0.0 0.75 9.5 0.0 3.1 2 0 0 2 2 2 1 Part of AAA domain AAA_18 PF13238.1 AEO53398.1 - 0.0047 17.2 7.9 0.15 12.3 0.0 3.4 4 0 0 4 4 3 2 AAA domain AAA_25 PF13481.1 AEO53398.1 - 0.008 15.5 0.3 2.4 7.5 0.0 2.8 2 1 0 2 2 2 1 AAA domain SRP54 PF00448.17 AEO53398.1 - 0.0083 15.5 0.0 0.48 9.8 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_28 PF13521.1 AEO53398.1 - 0.0095 15.9 1.0 7.2 6.5 0.0 3.6 3 1 0 3 3 3 0 AAA domain ResIII PF04851.10 AEO53398.1 - 0.014 15.1 1.1 13 5.6 0.0 3.8 3 1 0 4 4 4 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.4 AEO53398.1 - 0.023 13.3 0.0 1.8 7.1 0.0 2.7 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain AAA_10 PF12846.2 AEO53398.1 - 0.039 13.4 0.0 0.7 9.2 0.0 3.0 2 2 1 3 3 3 0 AAA-like domain Seryl_tRNA_N PF02403.17 AEO53398.1 - 0.041 13.9 15.2 0.029 14.3 9.0 2.0 2 0 0 2 2 1 0 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 AEO53398.1 - 0.044 13.3 11.9 0.039 13.5 7.1 1.7 2 0 0 2 2 1 0 IncA protein Mg_chelatase PF01078.16 AEO53398.1 - 0.044 12.9 0.2 2.5 7.1 0.0 2.9 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI PduV-EutP PF10662.4 AEO53398.1 - 0.066 12.6 0.0 1.1 8.7 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 AEO53398.1 - 0.072 13.5 0.1 4.7 7.7 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_24 PF13479.1 AEO53398.1 - 0.084 12.4 0.0 2.1 7.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 AEO53398.1 - 0.13 11.7 0.1 1.8 8.0 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ADIP PF11559.3 AEO53398.1 - 0.2 11.5 13.2 0.39 10.6 9.2 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding V_ATPase_I PF01496.14 AEO53398.1 - 0.22 9.3 3.9 0.31 8.8 2.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 AEO53398.1 - 0.32 10.0 8.3 0.5 9.3 5.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 OEP PF02321.13 AEO53398.1 - 0.58 9.7 13.2 1.4 8.4 9.1 1.6 1 0 0 1 1 1 0 Outer membrane efflux protein DUF724 PF05266.9 AEO53398.1 - 3.6 7.1 12.0 6 6.4 8.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Atg14 PF10186.4 AEO53398.1 - 8.9 5.1 9.4 17 4.2 6.5 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Arf PF00025.16 AEO53399.1 - 1.8e-78 261.7 0.3 2.2e-78 261.5 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 AEO53399.1 - 8.2e-14 51.2 0.0 1e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 AEO53399.1 - 5.5e-13 48.6 0.0 6e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 AEO53399.1 - 1.6e-12 46.8 1.1 5e-09 35.3 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 AEO53399.1 - 3.1e-11 42.8 0.0 3.8e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 AEO53399.1 - 1.4e-08 35.2 0.0 2e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 AEO53399.1 - 9.8e-06 25.5 0.0 1.3e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 AEO53399.1 - 0.0023 17.0 0.1 0.0053 15.8 0.0 1.5 2 0 0 2 2 2 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 AEO53399.1 - 0.013 14.9 0.1 0.095 12.1 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 AEO53399.1 - 0.042 13.7 0.2 0.085 12.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain EMP24_GP25L PF01105.19 AEO53400.1 - 4.2e-46 156.9 0.0 4.8e-46 156.7 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Dioxygenase_C PF00775.16 AEO53400.1 - 0.005 16.1 0.0 0.0081 15.4 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase SpoU_methylase PF00588.14 AEO53400.1 - 0.053 13.3 0.0 1.3 8.8 0.0 2.1 1 1 1 2 2 2 0 SpoU rRNA Methylase family DUF3405 PF11885.3 AEO53401.1 - 2.9e-217 721.8 0.0 3.8e-217 721.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Glycophorin_A PF01102.13 AEO53401.1 - 0.00054 19.7 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 Glycophorin A FAD_binding_2 PF00890.19 AEO53402.1 - 2.8e-124 415.1 3.1 3.5e-124 414.8 2.1 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 AEO53402.1 - 1.8e-48 163.6 1.1 2.7e-48 163.0 0.8 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 AEO53402.1 - 4.1e-07 30.0 0.0 0.0023 17.8 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 AEO53402.1 - 1e-05 24.7 0.3 0.0079 15.3 0.0 2.4 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 AEO53402.1 - 6.2e-05 22.0 2.5 0.0099 14.7 1.1 2.4 3 0 0 3 3 3 2 Glucose inhibited division protein A DAO PF01266.19 AEO53402.1 - 0.0012 17.8 0.2 0.0038 16.1 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 AEO53402.1 - 0.0045 16.1 0.6 0.0076 15.3 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 AEO53402.1 - 0.05 13.6 1.4 1.1 9.2 0.1 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 AEO53402.1 - 0.081 11.3 1.2 0.24 9.8 0.4 2.1 2 0 0 2 2 2 0 HI0933-like protein DUF3818 PF12825.2 AEO53403.1 - 5.4e-108 360.6 6.4 7.3e-81 271.4 0.7 2.2 1 1 1 2 2 2 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 AEO53403.1 - 2.8e-43 146.8 1.1 6.4e-43 145.6 0.8 1.6 1 0 0 1 1 1 1 PX-associated PX PF00787.19 AEO53403.1 - 2.4e-14 53.1 0.4 6.3e-13 48.5 0.0 3.2 2 1 0 2 2 2 1 PX domain Myc_N PF01056.13 AEO53403.1 - 0.054 12.6 1.6 0.1 11.7 1.1 1.4 1 0 0 1 1 1 0 Myc amino-terminal region Spc7 PF08317.6 AEO53404.1 - 0.022 13.4 2.2 0.032 12.8 1.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Matrilin_ccoil PF10393.4 AEO53404.1 - 0.034 13.5 0.3 0.2 11.0 0.0 2.3 1 1 1 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF2077 PF09850.4 AEO53404.1 - 0.039 13.3 0.2 0.11 11.8 0.1 1.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2077) Atg14 PF10186.4 AEO53404.1 - 0.079 11.8 3.9 0.13 11.1 2.7 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Med9 PF07544.8 AEO53404.1 - 0.088 12.5 2.7 0.13 12.0 1.0 1.8 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 FUSC PF04632.7 AEO53404.1 - 0.31 9.4 3.1 0.45 8.8 2.2 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Syntaxin PF00804.20 AEO53404.1 - 0.42 10.7 3.6 0.33 11.1 1.1 1.8 2 0 0 2 2 2 0 Syntaxin IncA PF04156.9 AEO53404.1 - 1.2 8.6 9.2 6.7 6.2 6.4 2.1 1 1 0 1 1 1 0 IncA protein MbeD_MobD PF04899.7 AEO53404.1 - 5.5 6.9 6.8 6 6.8 0.3 2.7 1 1 1 2 2 2 0 MbeD/MobD like Cgr1 PF03879.9 AEO53405.1 - 4e-39 133.1 26.3 4.6e-39 132.9 18.2 1.0 1 0 0 1 1 1 1 Cgr1 family PRP1_N PF06424.7 AEO53405.1 - 0.16 12.3 9.4 0.19 12.0 6.5 1.1 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal RR_TM4-6 PF06459.7 AEO53405.1 - 0.35 10.7 12.3 0.42 10.4 8.5 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Silic_transp PF03842.8 AEO53405.1 - 0.55 8.2 3.2 0.56 8.2 2.2 1.1 1 0 0 1 1 1 0 Silicon transporter DDRGK PF09756.4 AEO53405.1 - 3.7 6.9 20.2 4.3 6.7 14.0 1.2 1 0 0 1 1 1 0 DDRGK domain GAGA_bind PF06217.7 AEO53405.1 - 3.8 7.3 9.5 4.4 7.1 6.6 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2570 PF10828.3 AEO53405.1 - 6 6.5 8.5 7.9 6.1 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) UQ_con PF00179.21 AEO53407.1 - 6.3e-30 103.4 0.0 7.4e-30 103.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AEO53407.1 - 0.0001 22.0 0.0 0.00013 21.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 AEO53407.1 - 0.071 13.0 0.0 0.075 12.9 0.0 1.2 1 0 0 1 1 1 0 RWD domain Anp1 PF03452.9 AEO53408.1 - 3e-110 367.6 0.0 3.7e-110 367.3 0.0 1.0 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 AEO53408.1 - 0.037 13.7 0.0 0.062 12.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 Proteasom_Rpn13 PF04683.8 AEO53409.1 - 2.8e-28 97.8 0.0 4.2e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor L27_2 PF09045.5 AEO53409.1 - 0.14 11.7 0.3 0.26 10.8 0.2 1.4 1 0 0 1 1 1 0 L27_2 RRM_1 PF00076.17 AEO53410.1 - 1.5e-12 46.9 0.1 6.1e-05 22.5 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO53410.1 - 2.6e-12 46.5 0.1 1.1e-05 25.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO53410.1 - 3.6e-05 23.5 0.0 0.00024 20.8 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2201_N PF13203.1 AEO53410.1 - 0.13 11.4 9.8 0.044 12.9 2.4 2.1 2 0 0 2 2 2 0 Putative metallopeptidase domain RAP1 PF07218.6 AEO53410.1 - 0.75 7.8 6.0 1.1 7.2 4.2 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) AICARFT_IMPCHas PF01808.13 AEO53411.1 - 3.3e-113 377.9 0.0 4.5e-113 377.4 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 AEO53411.1 - 1.6e-23 82.4 0.0 3.1e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain DUF1237 PF06824.6 AEO53412.1 - 6.9e-183 608.0 0.0 8.4e-183 607.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) Tim54 PF11711.3 AEO53412.1 - 2.9 6.3 13.0 0.16 10.5 0.2 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Myc_N PF01056.13 AEO53412.1 - 4.3 6.3 16.2 0.043 12.9 2.8 2.3 2 0 0 2 2 2 0 Myc amino-terminal region Zip PF02535.17 AEO53412.1 - 6.9 5.5 4.6 16 4.4 0.1 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter Abhydro_lipase PF04083.11 AEO53413.1 - 1.4e-19 69.2 0.0 2.8e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 AEO53413.1 - 3.2e-07 30.4 5.3 3.2e-07 30.4 3.7 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO53413.1 - 0.00022 20.9 0.0 0.00057 19.6 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO53413.1 - 0.023 14.2 0.1 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold AAA PF00004.24 AEO53414.1 - 1.7e-49 167.3 0.0 2.4e-43 147.5 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 AEO53414.1 - 6.8e-05 22.3 0.2 0.00046 19.6 0.0 2.3 2 1 0 2 2 1 1 AAA domain AAA_17 PF13207.1 AEO53414.1 - 0.00013 22.7 0.0 0.00047 20.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 AEO53414.1 - 0.00021 20.3 0.0 0.00058 18.9 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 AEO53414.1 - 0.00069 19.6 0.1 0.022 14.7 0.0 2.8 1 1 1 2 2 2 1 AAA ATPase domain Parvo_NS1 PF01057.12 AEO53414.1 - 0.0007 18.5 0.0 0.0012 17.8 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_22 PF13401.1 AEO53414.1 - 0.00091 19.3 0.0 0.0039 17.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 AEO53414.1 - 0.0012 18.2 0.0 0.0025 17.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 AEO53414.1 - 0.0025 17.5 0.1 0.018 14.7 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_2 PF07724.9 AEO53414.1 - 0.0034 17.3 0.0 0.0078 16.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 AEO53414.1 - 0.011 14.5 0.0 0.016 13.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus RNA_helicase PF00910.17 AEO53414.1 - 0.013 15.6 0.0 0.036 14.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.9 AEO53414.1 - 0.026 14.2 0.0 0.084 12.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 AEO53414.1 - 0.026 13.6 0.1 0.048 12.8 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KaiC PF06745.8 AEO53414.1 - 0.031 13.3 0.0 0.075 12.1 0.0 1.5 1 0 0 1 1 1 0 KaiC PhoH PF02562.11 AEO53414.1 - 0.04 13.1 0.0 0.08 12.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_14 PF13173.1 AEO53414.1 - 0.057 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 AEO53414.1 - 0.069 13.4 0.4 0.18 12.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.1 AEO53414.1 - 0.092 12.6 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 AEO53414.1 - 0.13 11.1 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.21 AEO53414.1 - 0.14 11.6 0.0 1.7 8.1 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.1 AEO53414.1 - 0.17 11.4 0.2 0.3 10.6 0.1 1.3 1 0 0 1 1 1 0 AAA domain PPV_E1_C PF00519.12 AEO53414.1 - 0.32 9.5 0.0 0.51 8.8 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase SH3BGR PF04908.10 AEO53415.1 - 1.2e-05 25.1 0.0 4.3e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 SH3-binding, glutamic acid-rich protein Hid1 PF12722.2 AEO53415.1 - 6.2 4.3 8.9 7 4.1 6.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Corona_nucleoca PF00937.13 AEO53416.1 - 0.55 9.1 5.1 0.78 8.6 3.5 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein PDEase_II PF02112.10 AEO53417.1 - 0.14 11.0 2.4 0.15 10.9 1.7 1.1 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II Argos PF11581.3 AEO53418.1 - 0.028 14.3 1.1 0.028 14.3 0.8 1.3 1 1 0 1 1 1 0 Antagonist of EGFR signalling, Argos Lipase PF00151.14 AEO53418.1 - 0.14 11.3 1.9 0.14 11.3 1.3 1.1 1 0 0 1 1 1 0 Lipase DUF3439 PF11921.3 AEO53418.1 - 0.43 10.3 12.0 0.54 10.0 8.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Siva PF05458.7 AEO53418.1 - 0.44 10.0 8.2 0.5 9.9 5.7 1.1 1 0 0 1 1 1 0 Cd27 binding protein (Siva) zf-HIT PF04438.11 AEO53418.1 - 1.2 8.8 7.7 0.43 10.2 0.5 2.5 1 1 1 2 2 2 0 HIT zinc finger EMI PF07546.8 AEO53418.1 - 1.3 9.5 8.1 1.6 9.2 5.6 1.2 1 0 0 1 1 1 0 EMI domain FYVE PF01363.16 AEO53419.1 - 1.1e-21 76.5 0.8 1.1e-21 76.5 0.6 2.7 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.1 AEO53419.1 - 3.7e-08 33.0 5.4 3.7e-08 33.0 3.8 3.5 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 AEO53419.1 - 0.0002 20.9 2.5 0.0002 20.9 1.7 3.7 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AEO53419.1 - 0.011 15.7 4.7 0.011 15.7 3.3 3.8 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.11 AEO53419.1 - 0.019 14.8 1.5 0.019 14.8 1.1 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger Elf1 PF05129.8 AEO53419.1 - 0.045 13.4 11.8 0.052 13.2 1.1 3.1 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like Rad50_zn_hook PF04423.9 AEO53419.1 - 0.071 12.5 8.1 0.088 12.2 0.6 2.6 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-piccolo PF05715.8 AEO53419.1 - 0.15 12.0 8.5 1.1 9.3 3.0 2.9 2 0 0 2 2 2 0 Piccolo Zn-finger zf-DHHC PF01529.15 AEO53419.1 - 0.2 11.0 4.1 0.34 10.2 1.6 2.1 2 0 0 2 2 2 0 DHHC palmitoyltransferase DUF605 PF04652.11 AEO53419.1 - 0.22 10.9 14.6 0.33 10.2 10.2 1.3 1 0 0 1 1 1 0 Vta1 like zf-rbx1 PF12678.2 AEO53419.1 - 0.36 10.9 17.3 0.18 11.9 5.5 3.4 3 1 0 3 3 3 0 RING-H2 zinc finger zinc_ribbon_2 PF13240.1 AEO53419.1 - 0.96 9.0 7.9 2.7 7.6 0.2 3.4 3 0 0 3 3 3 0 zinc-ribbon domain dCMP_cyt_deam_1 PF00383.17 AEO53420.1 - 2.3e-14 52.8 0.1 3.2e-14 52.4 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 AEO53420.1 - 6.1e-08 32.7 0.8 8e-07 29.0 0.1 2.1 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 AEO53420.1 - 0.0015 17.9 0.8 0.22 10.8 0.1 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases ABC_membrane PF00664.18 AEO53421.1 - 1.5e-72 244.3 35.3 2.3e-38 132.1 6.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 AEO53421.1 - 9.5e-62 207.3 0.0 2.1e-32 112.3 0.0 3.3 3 0 0 3 3 3 3 ABC transporter SMC_N PF02463.14 AEO53421.1 - 3.2e-12 46.1 6.0 0.00035 19.8 1.5 4.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 AEO53421.1 - 3.9e-12 46.7 0.1 0.011 15.7 0.0 4.3 2 2 1 3 3 3 3 AAA domain DUF3987 PF13148.1 AEO53421.1 - 9.4e-11 40.8 1.0 7.3e-10 37.9 0.5 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) ABC_ATPase PF09818.4 AEO53421.1 - 3.3e-09 35.8 0.3 0.0043 15.7 0.0 3.2 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 AEO53421.1 - 4.3e-09 36.6 1.2 6.9e-05 22.9 0.1 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.1 AEO53421.1 - 2.3e-08 33.4 0.2 0.00097 18.6 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 AEO53421.1 - 1.7e-07 32.1 0.1 0.008 16.9 0.1 2.8 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 AEO53421.1 - 2.7e-06 27.1 2.0 0.24 10.9 0.1 4.0 3 1 0 3 3 3 2 AAA domain AAA_25 PF13481.1 AEO53421.1 - 5.7e-06 25.8 1.7 1.3 8.4 0.0 4.5 5 0 0 5 5 4 2 AAA domain DUF258 PF03193.11 AEO53421.1 - 1.5e-05 24.2 0.0 0.2 10.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 AEO53421.1 - 1.6e-05 25.0 0.9 0.37 10.9 0.0 3.9 3 1 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 AEO53421.1 - 0.0001 22.1 1.8 0.22 11.4 0.1 3.9 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 AEO53421.1 - 0.00018 21.0 0.3 0.035 13.5 0.0 3.4 4 0 0 4 4 4 1 AAA-like domain AAA_15 PF13175.1 AEO53421.1 - 0.00027 20.1 0.0 0.25 10.3 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.1 AEO53421.1 - 0.00033 20.9 0.3 0.6 10.4 0.2 2.5 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 AEO53421.1 - 0.00041 20.0 0.1 0.45 10.2 0.0 3.3 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 AEO53421.1 - 0.0018 18.1 0.4 0.22 11.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain BLVR PF06375.6 AEO53421.1 - 0.0021 17.9 7.4 0.0042 16.9 5.1 1.4 1 0 0 1 1 1 1 Bovine leukaemia virus receptor (BLVR) AAA_28 PF13521.1 AEO53421.1 - 0.015 15.2 0.0 9.5 6.1 0.0 2.9 3 0 0 3 3 2 0 AAA domain DUF87 PF01935.12 AEO53421.1 - 0.016 15.0 0.3 2.2 8.0 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function DUF87 MobB PF03205.9 AEO53421.1 - 0.026 14.2 0.3 5.7 6.6 0.1 3.1 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 AEO53421.1 - 0.027 14.3 0.2 12 5.7 0.1 3.4 3 0 0 3 3 3 0 AAA domain PRK PF00485.13 AEO53421.1 - 0.047 13.2 0.1 3.3 7.2 0.1 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ATP_bind_1 PF03029.12 AEO53421.1 - 0.077 12.5 0.0 4.2 6.8 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.13 AEO53421.1 - 0.11 11.9 0.5 3.1 7.2 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family FAM176 PF14851.1 AEO53421.1 - 1.1 8.8 3.6 2.6 7.6 2.5 1.5 1 0 0 1 1 1 0 FAM176 family AAA_23 PF13476.1 AEO53421.1 - 2.9 8.1 16.4 0.33 11.2 0.2 3.1 2 1 1 3 3 2 0 AAA domain UCR_Fe-S_N PF10399.4 AEO53421.1 - 4.2 6.6 8.1 0.72 9.0 0.1 3.3 3 0 0 3 3 3 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal tRNA-synt_His PF13393.1 AEO53422.1 - 3.1e-34 118.4 0.0 7.2e-28 97.5 0.0 2.4 2 1 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.15 AEO53422.1 - 2.6e-12 46.5 0.0 4.6e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.20 AEO53422.1 - 1.2e-09 37.9 0.0 3.8e-09 36.3 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.15 AEO53422.1 - 0.0031 16.3 0.0 0.49 9.1 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) Pkinase PF00069.20 AEO53424.1 - 9.5e-71 237.9 0.0 1.3e-70 237.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO53424.1 - 3.8e-33 114.6 0.0 6.8e-33 113.8 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO53424.1 - 7.5e-06 25.1 0.0 1.1e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 AEO53424.1 - 0.0031 16.8 0.0 0.0074 15.6 0.0 1.6 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 AEO53424.1 - 0.0056 15.7 0.0 0.011 14.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family 5_nucleotid PF05761.9 AEO53424.1 - 0.086 11.3 0.0 0.13 10.7 0.0 1.2 1 0 0 1 1 1 0 5' nucleotidase family UQ_con PF00179.21 AEO53425.1 - 1.1e-25 89.6 0.1 1.3e-25 89.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AEO53425.1 - 2.2e-08 33.9 0.0 3.9e-08 33.1 0.0 1.5 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 AEO53425.1 - 0.00017 21.4 0.0 0.0002 21.2 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 AEO53425.1 - 0.018 14.7 0.1 0.025 14.2 0.1 1.2 1 0 0 1 1 1 0 UEV domain UFC1 PF08694.6 AEO53425.1 - 0.15 11.5 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Sec1 PF00995.18 AEO53426.1 - 6.8e-142 473.9 0.0 7.7e-142 473.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Amino_oxidase PF01593.19 AEO53427.1 - 7.8e-89 298.7 0.0 1.4e-88 297.9 0.0 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.12 AEO53427.1 - 1.8e-09 37.5 0.0 3.5e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain HMG_box_2 PF09011.5 AEO53427.1 - 4.7e-08 33.2 1.4 9.5e-08 32.3 1.0 1.5 1 0 0 1 1 1 1 HMG-box domain NAD_binding_8 PF13450.1 AEO53427.1 - 1e-06 28.6 0.0 2.6e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box PF00505.14 AEO53427.1 - 1.4e-06 28.4 2.3 1.4e-06 28.4 1.6 2.7 3 0 0 3 3 3 1 HMG (high mobility group) box ATP-synt PF00231.14 AEO53428.1 - 3.7e-72 243.1 2.1 4.3e-72 242.9 1.5 1.0 1 0 0 1 1 1 1 ATP synthase Topoisom_I_N PF02919.10 AEO53429.1 - 6.8e-100 332.7 3.4 6.8e-100 332.7 2.4 2.7 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 AEO53429.1 - 1.4e-85 286.1 6.0 1.4e-85 286.1 4.1 2.4 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 AEO53429.1 - 2.3e-30 104.0 0.1 2.3e-30 104.0 0.0 2.3 3 0 0 3 3 3 1 C-terminal topoisomerase domain PspB PF06667.7 AEO53429.1 - 0.17 11.8 0.6 0.7 9.8 0.3 2.2 2 0 0 2 2 2 0 Phage shock protein B Glyco_hydro_16 PF00722.16 AEO53430.1 - 1.4e-43 148.2 0.2 2.3e-43 147.6 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 MARVEL PF01284.18 AEO53431.1 - 0.084 12.6 2.5 0.19 11.5 1.6 1.6 1 1 0 1 1 1 0 Membrane-associating domain GVQW PF13900.1 AEO53431.1 - 0.27 11.2 2.9 0.52 10.3 2.0 1.4 1 0 0 1 1 1 0 Putative binding domain Form-deh_trans PF09163.6 AEO53431.1 - 0.34 10.4 3.1 4.9 6.7 3.1 2.0 2 0 0 2 2 2 0 Formate dehydrogenase N, transmembrane Aminotran_1_2 PF00155.16 AEO53433.1 - 1.2e-16 60.7 0.0 1.6e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 AEO53433.1 - 1.9e-06 26.6 0.0 3e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase p450 PF00067.17 AEO53434.1 - 5.5e-59 199.8 0.0 7.7e-59 199.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_20 PF00728.17 AEO53435.1 - 9.9e-88 294.6 0.0 1.2e-87 294.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 AEO53435.1 - 1.7e-26 93.3 0.0 3.1e-26 92.5 0.0 1.4 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 AEO53435.1 - 1.2e-08 35.5 0.0 4.8e-08 33.5 0.0 2.0 2 1 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 Orthopox_A43R PF06517.6 AEO53435.1 - 0.11 12.1 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Orthopoxvirus A43R protein zf-CCCH_2 PF14608.1 AEO53436.1 - 9.7e-06 25.3 53.8 1.8e-05 24.5 4.8 5.5 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type FlxA PF14282.1 AEO53436.1 - 0.019 14.9 0.5 0.019 14.9 0.3 2.5 2 0 0 2 2 2 0 FlxA-like protein NAD_binding_8 PF13450.1 AEO53437.1 - 2.7e-09 36.9 0.0 1.8e-08 34.2 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 AEO53437.1 - 1.9e-07 30.3 0.1 1e-05 24.6 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 AEO53437.1 - 4e-07 29.4 0.0 0.00053 19.1 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 AEO53437.1 - 1.6e-05 25.2 0.2 0.028 14.8 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AEO53437.1 - 0.014 15.4 0.0 0.45 10.5 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 AEO53437.1 - 0.13 11.3 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Thi4 family DUF3052 PF11253.3 AEO53437.1 - 0.17 11.4 0.0 1.7 8.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3052) Med14 PF08638.6 AEO53438.1 - 1.2e-74 249.7 0.0 2.1e-74 249.0 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit MED14 G6PD_C PF02781.11 AEO53439.1 - 4e-135 449.3 0.0 5.4e-135 448.9 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 AEO53439.1 - 4.2e-64 216.1 0.0 6.9e-64 215.4 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Ribosomal_L35Ae PF01247.13 AEO53440.1 - 4.3e-42 141.8 0.4 4.8e-42 141.6 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 AEO53440.1 - 9e-05 22.3 0.0 0.083 12.8 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain DUF2406 PF10295.4 AEO53441.1 - 5.1e-19 68.5 1.0 1.3e-18 67.2 0.1 2.2 2 0 0 2 2 2 1 Uncharacterised protein (DUF2406) VMA21 PF09446.5 AEO53442.1 - 8.3e-15 54.4 6.9 1.2e-14 53.9 4.8 1.2 1 0 0 1 1 1 1 VMA21-like domain DUF4282 PF14110.1 AEO53442.1 - 2.1 8.6 4.7 2.9 8.1 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) SNF2_N PF00176.18 AEO53443.1 - 6.2e-59 199.2 0.0 9.3e-59 198.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AEO53443.1 - 3.8e-14 52.2 0.0 8.8e-14 51.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Latarcin PF10279.4 AEO53443.1 - 0.034 14.3 0.6 12 6.1 0.0 3.3 3 0 0 3 3 3 0 Latarcin precursor DUF3336 PF11815.3 AEO53444.1 - 2.6e-34 117.7 0.0 8.1e-34 116.2 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.17 AEO53444.1 - 3.3e-13 50.0 0.0 6.2e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase NurA PF09376.5 AEO53445.1 - 0.0048 16.4 1.7 0.0052 16.2 1.2 1.1 1 0 0 1 1 1 1 NurA domain RVT_1 PF00078.22 AEO53445.1 - 0.014 14.7 0.6 0.016 14.5 0.4 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Lipase_GDSL_2 PF13472.1 AEO53449.1 - 7.3e-17 62.0 1.1 1.2e-16 61.3 0.8 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 AEO53449.1 - 1.3e-14 54.6 0.0 1.2e-13 51.4 0.0 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase BOP1NT PF08145.7 AEO53450.1 - 1.9e-103 345.7 9.2 2.9e-103 345.1 6.4 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 AEO53450.1 - 4.1e-27 93.0 2.0 7.6e-11 41.4 0.0 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat Zn_clus PF00172.13 AEO53451.1 - 2.8e-07 30.3 9.7 6.8e-07 29.1 6.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SURF4 PF02077.10 AEO53452.1 - 7.1e-98 327.2 8.8 8e-98 327.0 6.1 1.0 1 0 0 1 1 1 1 SURF4 family Peptidase_A24 PF01478.13 AEO53452.1 - 1.9 8.6 16.1 0.68 10.1 1.1 2.7 2 1 0 2 2 2 0 Type IV leader peptidase family Halogen_Hydrol PF10112.4 AEO53452.1 - 2.9 7.2 6.1 5.7 6.2 0.4 2.6 3 0 0 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Wzy_C PF04932.10 AEO53452.1 - 4.7 6.9 12.6 0.13 12.0 2.9 2.2 2 0 0 2 2 2 0 O-Antigen ligase HR_lesion PF05514.6 AEO53452.1 - 9.7 6.0 11.5 0.58 9.9 1.5 3.2 3 2 1 4 4 4 0 HR-like lesion-inducing VSP PF03302.8 AEO53453.1 - 0.032 12.8 1.5 0.044 12.4 1.0 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein Alg6_Alg8 PF03155.10 AEO53455.1 - 4.9e-131 437.8 24.0 4.3e-82 276.4 5.9 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family BRO1 PF03097.13 AEO53456.1 - 1.6e-05 23.8 0.0 2.4e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 BRO1-like domain Leo1 PF04004.8 AEO53457.1 - 2.8e-32 111.7 0.1 2.8e-32 111.7 0.0 2.2 2 0 0 2 2 2 1 Leo1-like protein Mob1_phocein PF03637.12 AEO53458.1 - 3.7e-36 124.4 0.9 1e-17 64.3 0.3 2.1 2 0 0 2 2 2 2 Mob1/phocein family OSTMP1 PF09777.4 AEO53458.1 - 0.021 13.9 0.2 0.038 13.1 0.1 1.3 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor TraC PF07820.7 AEO53458.1 - 0.093 12.9 1.2 0.16 12.1 0.8 1.4 1 0 0 1 1 1 0 TraC-like protein DUF2188 PF09954.4 AEO53458.1 - 4.3 7.3 5.6 2.2 8.2 2.1 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) DUF3237 PF11578.3 AEO53459.1 - 7.3e-25 87.0 0.0 8.2e-25 86.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) CorA PF01544.13 AEO53460.1 - 4.5e-42 144.0 1.2 7.5e-40 136.7 0.8 2.2 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein CSTF2_hinge PF14327.1 AEO53461.1 - 1.2e-30 105.4 0.8 2.8e-30 104.2 0.6 1.7 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 AEO53461.1 - 2e-22 78.5 0.0 3.2e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO53461.1 - 2.1e-17 62.8 0.0 4.2e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO53461.1 - 3.3e-06 26.8 0.0 4.8e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 AEO53461.1 - 3.8e-05 22.8 3.8 3.8e-05 22.8 2.7 2.7 3 0 0 3 3 3 1 Transcription termination and cleavage factor C-terminal DUF3135 PF11333.3 AEO53461.1 - 0.32 11.1 4.3 0.33 11.1 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) PAT1 PF09770.4 AEO53461.1 - 1.4 7.0 5.4 1.6 6.8 3.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Band_7 PF01145.20 AEO53462.1 - 3.4e-25 88.9 1.4 4.9e-25 88.4 1.0 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Methyltransf_5 PF01795.14 AEO53462.1 - 0.11 11.7 1.8 0.18 11.0 1.3 1.3 1 1 0 1 1 1 0 MraW methylase family ubiquitin PF00240.18 AEO53463.1 - 1.9e-23 81.6 0.1 2.1e-23 81.5 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 AEO53463.1 - 3.6e-13 49.0 0.1 3.9e-13 48.8 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 AEO53463.1 - 0.014 15.6 0.1 0.021 15.0 0.0 1.4 1 1 0 1 1 1 0 Ubiquitin-like domain DUF2407 PF10302.4 AEO53463.1 - 0.08 13.1 0.0 0.09 12.9 0.0 1.1 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Elongin_A PF06881.6 AEO53464.1 - 6.5e-16 58.6 2.5 1.4e-15 57.5 1.7 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A SMN PF06003.7 AEO53464.1 - 0.00066 18.8 0.4 0.00066 18.8 0.3 2.6 2 1 1 3 3 3 1 Survival motor neuron protein (SMN) THOC7 PF05615.8 AEO53465.1 - 3.3e-44 150.5 1.1 3.3e-44 150.5 0.8 1.8 2 0 0 2 2 2 1 Tho complex subunit 7 RTBV_P46 PF06216.6 AEO53465.1 - 0.071 11.9 3.8 0.097 11.4 0.5 2.0 2 0 0 2 2 2 0 Rice tungro bacilliform virus P46 protein ATG16 PF08614.6 AEO53465.1 - 0.69 9.7 10.9 0.95 9.2 6.1 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) MSA-2c PF12238.3 AEO53465.1 - 1.3 8.6 3.2 1.1 8.9 0.1 2.2 2 0 0 2 2 2 0 Merozoite surface antigen 2c AAA_13 PF13166.1 AEO53465.1 - 1.3 7.3 4.0 3.1 6.1 2.8 1.5 1 1 0 1 1 1 0 AAA domain FUSC PF04632.7 AEO53465.1 - 4.2 5.6 11.3 5.7 5.2 7.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2664 PF10867.3 AEO53465.1 - 8.2 7.1 9.1 0.98 10.0 2.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2664) Mnd1 PF03962.10 AEO53465.1 - 9.5 5.8 10.8 6 6.4 0.6 2.3 1 1 1 2 2 2 0 Mnd1 family TBCA PF02970.11 AEO53466.1 - 1.5e-19 69.8 8.4 2e-19 69.4 5.8 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor A CALCOCO1 PF07888.6 AEO53466.1 - 0.0027 16.1 8.6 0.003 15.9 5.9 1.0 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like RRF PF01765.14 AEO53466.1 - 0.012 15.1 0.8 0.012 15.1 0.6 1.9 1 1 1 2 2 2 0 Ribosome recycling factor DUF2972 PF11186.3 AEO53466.1 - 0.036 13.9 3.3 0.068 13.0 2.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2972) AAA_13 PF13166.1 AEO53466.1 - 0.099 11.0 7.6 0.12 10.7 5.2 1.1 1 0 0 1 1 1 0 AAA domain Flagellin_C PF00700.16 AEO53466.1 - 0.17 12.0 1.4 0.96 9.6 0.1 2.4 2 1 0 2 2 2 0 Bacterial flagellin C-terminal helical region OmpH PF03938.9 AEO53466.1 - 0.33 10.8 13.8 1.2 9.1 9.6 1.8 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Flagellin_N PF00669.15 AEO53466.1 - 0.36 10.6 4.0 2.8 7.7 0.2 2.2 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region DUF3994 PF13159.1 AEO53466.1 - 0.36 11.0 3.3 0.23 11.7 0.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3994) FlxA PF14282.1 AEO53466.1 - 0.61 10.0 8.2 0.86 9.5 5.7 1.3 1 0 0 1 1 1 0 FlxA-like protein IncA PF04156.9 AEO53466.1 - 0.67 9.5 8.6 0.92 9.0 5.9 1.2 1 0 0 1 1 1 0 IncA protein Tropomyosin PF00261.15 AEO53466.1 - 0.79 8.7 15.4 0.76 8.8 4.1 2.0 1 1 1 2 2 2 0 Tropomyosin DUF4404 PF14357.1 AEO53466.1 - 1.1 9.7 6.2 8.5 6.8 0.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) XhlA PF10779.4 AEO53466.1 - 1.2 9.0 12.4 3.5 7.5 2.1 2.8 1 1 1 2 2 2 0 Haemolysin XhlA CENP-Q PF13094.1 AEO53466.1 - 2 8.3 10.8 14 5.6 7.4 2.0 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Fib_alpha PF08702.5 AEO53466.1 - 2.6 8.1 5.5 7.2 6.7 3.5 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Tropomyosin_1 PF12718.2 AEO53466.1 - 2.8 7.8 16.2 4.9 6.9 4.3 1.9 1 1 0 1 1 1 0 Tropomyosin like E1-E2_ATPase PF00122.15 AEO53467.1 - 3.5e-64 216.0 6.5 2e-63 213.5 3.8 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 AEO53467.1 - 2.8e-46 157.3 6.3 2.8e-46 157.3 4.4 1.6 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 AEO53467.1 - 5.7e-32 111.8 0.0 5.9e-31 108.5 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AEO53467.1 - 8.5e-24 83.3 0.0 1.6e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 AEO53467.1 - 1.1e-21 76.0 0.0 3.4e-21 74.4 0.0 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 AEO53467.1 - 5.2e-17 62.6 0.2 1.9e-16 60.8 0.0 2.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 AEO53467.1 - 1.5e-08 34.5 0.5 6.3e-06 25.9 0.5 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 AEO53467.1 - 0.014 15.6 0.0 0.034 14.3 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Proteasome PF00227.21 AEO53468.1 - 5.2e-40 136.7 0.0 5.8e-40 136.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit TUG-UBL1 PF11470.3 AEO53469.1 - 4.5e-21 74.5 0.0 5.9e-12 45.3 0.0 3.3 3 0 0 3 3 3 2 GLUT4 regulating protein TUG UBX PF00789.15 AEO53469.1 - 0.01 15.8 0.0 0.048 13.7 0.0 2.1 2 0 0 2 2 2 0 UBX domain Allexi_40kDa PF05549.6 AEO53469.1 - 0.046 13.0 0.2 0.099 11.9 0.1 1.5 1 0 0 1 1 1 0 Allexivirus 40kDa protein RBD PF02196.10 AEO53469.1 - 0.076 12.7 0.0 0.24 11.2 0.0 1.8 1 0 0 1 1 1 0 Raf-like Ras-binding domain DUF605 PF04652.11 AEO53469.1 - 0.79 9.0 17.3 1.2 8.4 12.0 1.2 1 0 0 1 1 1 0 Vta1 like Jag_N PF14804.1 AEO53469.1 - 1.5 8.8 6.2 18 5.4 0.1 3.2 3 0 0 3 3 3 0 Jag N-terminus Ribosomal_L36e PF01158.13 AEO53470.1 - 2.9e-40 136.2 7.1 3.3e-40 136.0 4.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e CLTH PF10607.4 AEO53470.1 - 0.083 12.5 0.2 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain Lipase_3 PF01764.20 AEO53472.1 - 4.5e-30 104.1 0.0 6e-30 103.6 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 AEO53472.1 - 0.00012 22.0 0.1 0.00017 21.5 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO53472.1 - 0.00056 19.6 0.0 0.00093 18.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Glyco_trans_1_4 PF13692.1 AEO53472.1 - 0.0017 18.5 0.0 0.0035 17.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF2974 PF11187.3 AEO53472.1 - 0.021 14.1 0.0 0.27 10.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) PGAP1 PF07819.8 AEO53472.1 - 0.035 13.6 0.0 0.057 12.9 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_1 PF00561.15 AEO53472.1 - 0.08 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold 14-3-3 PF00244.15 AEO53473.1 - 5.1e-115 382.5 1.8 6.5e-115 382.1 1.2 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF837 PF05769.6 AEO53473.1 - 0.0038 16.7 0.4 5.6 6.4 0.0 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF837) DUF4085 PF13315.1 AEO53473.1 - 0.011 15.0 0.3 0.017 14.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) TPR_12 PF13424.1 AEO53473.1 - 0.025 14.4 0.5 9.7 6.2 0.1 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat GLYCAM-1 PF05242.6 AEO53473.1 - 0.076 12.9 0.1 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) MCM_N PF14551.1 AEO53473.1 - 0.27 11.7 1.7 7.9 6.9 1.2 2.3 1 1 0 1 1 1 0 MCM N-terminal domain Syja_N PF02383.13 AEO53475.1 - 4.5e-86 288.5 0.0 6.3e-86 288.0 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 AEO53475.1 - 6.9e-25 88.4 0.1 1.2e-24 87.6 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TPR_16 PF13432.1 AEO53476.1 - 1.1e-05 25.9 0.7 0.0025 18.4 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat Suf PF05843.9 AEO53476.1 - 2.7e-05 24.0 4.6 0.0051 16.5 0.1 3.2 2 1 1 3 3 3 2 Suppressor of forked protein (Suf) TPR_14 PF13428.1 AEO53476.1 - 1.4 9.7 8.9 11 6.9 0.1 5.7 6 2 2 8 8 8 0 Tetratricopeptide repeat peroxidase PF00141.18 AEO53477.1 - 2.3e-51 174.4 0.0 3.8e-51 173.7 0.0 1.3 1 0 0 1 1 1 1 Peroxidase ATP11 PF06644.6 AEO53478.1 - 2.7e-83 279.5 0.0 5.6e-83 278.5 0.0 1.5 1 1 0 1 1 1 1 ATP11 protein DUF2360 PF10152.4 AEO53478.1 - 0.024 14.9 7.2 0.033 14.4 5.0 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) PAT1 PF09770.4 AEO53478.1 - 0.14 10.3 10.5 0.16 10.1 7.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pex14_N PF04695.8 AEO53478.1 - 0.15 12.1 6.8 0.22 11.5 4.7 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF605 PF04652.11 AEO53478.1 - 0.2 10.9 14.3 0.25 10.6 9.9 1.1 1 0 0 1 1 1 0 Vta1 like Suf PF05843.9 AEO53478.1 - 0.26 10.9 5.2 0.34 10.5 3.6 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SRP-alpha_N PF04086.8 AEO53478.1 - 0.33 10.3 3.4 0.47 9.7 2.4 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal ORC6 PF05460.8 AEO53478.1 - 0.92 8.5 9.0 1.3 8.0 6.2 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF1183 PF06682.7 AEO53478.1 - 1.5 8.3 6.8 2.4 7.6 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) RAB3GAP2_N PF14655.1 AEO53478.1 - 1.9 7.4 3.9 2.9 6.7 2.7 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus AMP-binding PF00501.23 AEO53479.1 - 6e-91 304.9 0.0 7.6e-91 304.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 AEO53479.1 - 2.4e-15 57.2 0.6 5.3e-15 56.1 0.4 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Glyco_transf_54 PF04666.8 AEO53481.1 - 0.011 14.5 0.0 2.7 6.6 0.1 2.4 3 0 0 3 3 3 0 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region zf-C2H2 PF00096.21 AEO53482.1 - 0.0018 18.5 1.1 0.01 16.1 0.7 2.4 1 1 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AEO53482.1 - 0.02 15.2 1.4 0.02 15.2 1.0 2.4 2 1 0 2 2 2 0 C2H2-type zinc finger Fungal_trans PF04082.13 AEO53483.1 - 1.8e-06 27.0 1.3 2.4e-06 26.6 0.3 1.6 1 1 1 2 2 2 1 Fungal specific transcription factor domain Transformer PF06495.6 AEO53484.1 - 0.13 12.1 15.1 0.28 11.0 10.3 1.7 1 1 0 1 1 1 0 Fruit fly transformer protein Corona_nucleoca PF00937.13 AEO53484.1 - 1.1 8.1 10.0 1.6 7.5 6.9 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF4463 PF14703.1 AEO53485.1 - 0.092 13.2 0.5 0.29 11.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4463) AA_permease PF00324.16 AEO53486.1 - 1.6e-141 471.9 29.6 2e-141 471.6 20.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AEO53486.1 - 4.6e-38 130.8 30.3 6.2e-38 130.4 21.0 1.1 1 0 0 1 1 1 1 Amino acid permease Glyco_hydro_47 PF01532.15 AEO53487.1 - 4.1e-167 556.4 0.0 5.5e-167 555.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF4038 PF13204.1 AEO53487.1 - 0.0038 16.6 0.1 0.0081 15.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) Autophagy_act_C PF03987.10 AEO53488.1 - 9.4e-06 25.7 0.0 1.6e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain RRM_5 PF13893.1 AEO53489.1 - 2.5e-10 40.0 0.1 3.7e-10 39.5 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AEO53489.1 - 1.2e-09 37.6 0.0 3.2e-09 36.2 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO53489.1 - 3.7e-06 26.8 0.0 7.4e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 AEO53489.1 - 0.00043 19.8 0.0 0.00084 18.9 0.0 1.5 1 0 0 1 1 1 1 Calcipressin WD40 PF00400.27 AEO53490.1 - 5.6e-22 76.7 7.3 2.8e-08 33.3 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat Rax2 PF12768.2 AEO53490.1 - 0.003 16.8 0.0 0.0051 16.0 0.0 1.3 1 0 0 1 1 1 1 Cortical protein marker for cell polarity Pkinase PF00069.20 AEO53491.1 - 2.2e-68 230.2 0.0 3.2e-68 229.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO53491.1 - 6.2e-43 146.7 0.0 9.3e-43 146.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO53491.1 - 5.5e-10 38.6 0.0 9.4e-10 37.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like POLO_box PF00659.13 AEO53491.1 - 3.2e-08 33.4 0.0 7.4e-05 22.6 0.0 2.9 2 0 0 2 2 2 2 POLO box duplicated region Kdo PF06293.9 AEO53491.1 - 0.00079 18.5 0.0 0.0019 17.2 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family OPA3 PF07047.7 AEO53492.1 - 6.7e-44 148.9 2.4 9.2e-44 148.4 1.7 1.2 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) DUF2681 PF10883.3 AEO53492.1 - 0.0096 16.1 7.6 0.011 15.9 0.4 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2681) DUF4094 PF13334.1 AEO53492.1 - 0.077 13.3 0.8 0.3 11.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) DUF4140 PF13600.1 AEO53492.1 - 0.09 13.2 0.7 0.09 13.2 0.5 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) OmpH PF03938.9 AEO53492.1 - 0.91 9.4 8.6 2.6 7.9 3.0 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Mnd1 PF03962.10 AEO53492.1 - 4.6 6.8 12.3 2.1 7.9 3.1 2.1 2 0 0 2 2 2 0 Mnd1 family SBDS PF01172.13 AEO53494.1 - 1.8e-26 91.7 0.1 2.1e-26 91.5 0.1 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein RhoGEF PF00621.15 AEO53495.1 - 2.3e-23 83.0 0.0 3.7e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain PDZ_2 PF13180.1 AEO53496.1 - 1.9e-06 27.6 0.0 3.1e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.9 AEO53496.1 - 3.2e-06 27.1 0.0 6.7e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ PF00595.19 AEO53496.1 - 7.2e-05 22.8 0.1 0.00011 22.3 0.1 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) DUF3336 PF11815.3 AEO53496.1 - 0.03 13.8 0.0 0.049 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3336) Ras PF00071.17 AEO53497.1 - 4.5e-49 165.9 0.0 5.5e-49 165.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AEO53497.1 - 1.9e-15 57.4 0.0 3.8e-15 56.4 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 AEO53497.1 - 3.1e-10 39.5 0.0 4.2e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 AEO53497.1 - 0.00075 19.6 0.1 0.0056 16.8 0.1 2.1 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 AEO53497.1 - 0.005 16.0 0.0 0.0066 15.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Pox_A32 PF04665.7 AEO53497.1 - 0.026 13.8 0.1 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein G-alpha PF00503.15 AEO53497.1 - 0.035 12.8 1.1 0.85 8.2 0.0 2.3 2 1 0 2 2 2 0 G-protein alpha subunit AAA_33 PF13671.1 AEO53497.1 - 0.08 12.8 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 AEO53497.1 - 0.12 12.4 0.2 0.33 11.0 0.1 1.8 1 1 1 2 2 2 0 AAA domain SRPRB PF09439.5 AEO53497.1 - 0.13 11.4 0.0 0.25 10.5 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit WSC PF01822.14 AEO53498.1 - 1.7e-72 239.3 61.1 1e-19 70.2 9.2 4.3 4 0 0 4 4 4 4 WSC domain Glyoxal_oxid_N PF07250.6 AEO53498.1 - 4.1e-26 91.5 0.0 2.6e-25 88.9 0.0 2.2 3 0 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 AEO53498.1 - 1.9e-19 69.5 0.0 3.4e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) bZIP_1 PF00170.16 AEO53499.1 - 0.21 11.5 13.7 4.3 7.3 9.5 2.2 1 1 0 1 1 1 0 bZIP transcription factor RRN3 PF05327.6 AEO53500.1 - 3e-166 553.8 0.0 3e-166 553.8 0.0 1.7 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 Cut8_N PF14482.1 AEO53500.1 - 0.13 12.2 2.1 0.55 10.2 1.5 2.1 1 0 0 1 1 1 0 Cut8 proteasome-binding domain CBFD_NFYB_HMF PF00808.18 AEO53501.1 - 2e-29 101.4 1.1 2.7e-29 101.0 0.8 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 AEO53501.1 - 3.2e-07 30.3 0.1 5.6e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 AEO53501.1 - 0.00082 19.1 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 AEO53501.1 - 0.00091 18.9 0.0 0.0019 17.8 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 AEO53501.1 - 0.035 14.3 0.0 0.06 13.6 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Prefoldin_2 PF01920.15 AEO53502.1 - 7.7e-26 89.9 4.7 8.8e-26 89.7 3.3 1.0 1 0 0 1 1 1 1 Prefoldin subunit p25-alpha PF05517.7 AEO53502.1 - 0.014 15.6 0.9 0.42 10.8 0.1 2.0 2 0 0 2 2 2 0 p25-alpha DUF2089 PF09862.4 AEO53502.1 - 0.017 14.9 1.2 0.038 13.7 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2089) Taxilin PF09728.4 AEO53502.1 - 0.021 13.9 1.8 1.8 7.5 0.1 2.1 2 0 0 2 2 2 0 Myosin-like coiled-coil protein DUF2205 PF10224.4 AEO53502.1 - 0.037 13.6 6.3 0.24 11.0 0.4 2.1 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) Prefoldin PF02996.12 AEO53502.1 - 0.059 13.0 6.2 0.41 10.3 0.1 2.3 1 1 2 3 3 3 0 Prefoldin subunit Tho2 PF11262.3 AEO53502.1 - 0.065 12.2 0.9 2.5 7.0 0.0 2.0 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 UBN2 PF14223.1 AEO53502.1 - 0.067 12.9 0.2 0.56 10.0 0.0 2.1 1 1 1 2 2 2 0 gag-polypeptide of LTR copia-type TPR_MLP1_2 PF07926.7 AEO53502.1 - 0.068 12.9 6.5 0.31 10.7 0.1 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF641 PF04859.7 AEO53502.1 - 0.074 12.8 2.9 0.15 11.8 0.2 1.9 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) HrpB7 PF09486.5 AEO53502.1 - 0.094 12.6 2.2 1.8 8.4 0.0 2.0 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Syntaxin-6_N PF09177.6 AEO53502.1 - 0.12 12.7 1.7 8.4 6.8 0.3 2.1 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF3166 PF11365.3 AEO53502.1 - 0.16 12.4 1.7 6.3 7.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3166) DUF148 PF02520.12 AEO53502.1 - 0.18 11.5 4.8 0.6 9.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF148 IncA PF04156.9 AEO53502.1 - 0.35 10.4 3.0 0.69 9.4 2.1 1.5 1 1 0 1 1 1 0 IncA protein DASH_Dad3 PF08656.5 AEO53502.1 - 0.47 10.1 2.6 0.7 9.6 0.5 1.9 2 0 0 2 2 2 0 DASH complex subunit Dad3 DUF4200 PF13863.1 AEO53502.1 - 0.87 9.5 5.8 1.6 8.7 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Cytochrom_B562 PF07361.6 AEO53502.1 - 1.5 9.2 4.7 3.3 8.1 0.8 2.1 2 0 0 2 2 2 0 Cytochrome b562 Tup_N PF08581.5 AEO53502.1 - 1.8 8.7 5.7 3.1 8.0 2.0 2.0 2 0 0 2 2 2 0 Tup N-terminal DUF2956 PF11169.3 AEO53502.1 - 2 8.4 6.8 0.24 11.3 0.4 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2956) bZIP_Maf PF03131.12 AEO53502.1 - 2.5 8.4 6.0 6.2 7.1 0.1 2.1 2 0 0 2 2 2 0 bZIP Maf transcription factor Cmc1 PF08583.5 AEO53503.1 - 1.6e-16 59.8 4.1 1.9e-16 59.5 2.8 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CD45 PF12567.3 AEO53503.1 - 0.13 12.1 1.2 7.5 6.4 0.1 2.2 2 0 0 2 2 2 0 Leukocyte receptor CD45 Tmemb_14 PF03647.8 AEO53504.1 - 6.8e-24 84.0 5.8 7.6e-24 83.9 4.0 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF2416 PF10315.4 AEO53504.1 - 0.0053 16.9 0.3 0.013 15.7 0.2 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2416) zf-C2H2 PF00096.21 AEO53505.1 - 2.6e-05 24.2 21.9 0.0011 19.1 0.3 4.6 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 AEO53505.1 - 0.012 15.4 0.4 0.067 13.1 0.0 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_4 PF13894.1 AEO53505.1 - 0.015 15.5 0.4 0.015 15.5 0.3 4.8 4 0 0 4 4 4 0 C2H2-type zinc finger TRP PF06011.7 AEO53506.1 - 3.4e-132 441.1 16.6 4.2e-132 440.8 11.5 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 AEO53506.1 - 8.2e-41 139.3 1.6 1.2e-40 138.7 1.1 1.3 1 0 0 1 1 1 1 ML-like domain DUF2681 PF10883.3 AEO53506.1 - 3.7 7.8 8.4 16 5.7 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) Abhydrolase_6 PF12697.2 AEO53507.1 - 1.5e-15 57.7 10.1 1.9e-14 54.1 7.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO53507.1 - 1.7e-09 37.5 1.8 7.2e-09 35.5 1.5 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO53507.1 - 0.0012 18.4 1.2 0.16 11.4 0.8 2.7 2 1 0 2 2 2 2 alpha/beta hydrolase fold Lipase_3 PF01764.20 AEO53507.1 - 0.049 13.2 0.1 0.086 12.4 0.1 1.4 1 0 0 1 1 1 0 Lipase (class 3) Thioesterase PF00975.15 AEO53507.1 - 0.051 13.8 0.2 6.6 6.8 0.1 2.3 2 0 0 2 2 2 0 Thioesterase domain Dus PF01207.12 AEO53508.1 - 2.1e-38 131.9 0.3 1e-37 129.6 0.1 2.0 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) DUF2201_N PF13203.1 AEO53508.1 - 9.2 5.3 12.4 1.4 7.9 5.7 1.7 2 0 0 2 2 2 0 Putative metallopeptidase domain HAMP PF00672.20 AEO53510.1 - 2.4e-47 158.9 25.0 2.9e-10 40.1 0.2 8.0 8 1 1 9 9 9 6 HAMP domain HATPase_c PF02518.21 AEO53510.1 - 6.7e-30 103.0 0.4 2.2e-29 101.4 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 AEO53510.1 - 1.8e-27 95.5 0.4 3.5e-26 91.3 0.2 2.7 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 AEO53510.1 - 4.1e-18 65.1 0.5 4.1e-18 65.1 0.4 4.3 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain DUF883 PF05957.8 AEO53510.1 - 0.00023 21.4 8.8 0.99 9.8 0.1 6.0 4 1 1 5 5 5 2 Bacterial protein of unknown function (DUF883) NAAA-beta PF15508.1 AEO53510.1 - 0.15 12.4 5.1 9.3 6.6 0.1 5.7 4 2 2 6 6 6 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase HMG_box PF00505.14 AEO53511.1 - 1.6e-17 63.4 0.5 3e-17 62.6 0.4 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 AEO53511.1 - 2.9e-15 56.3 0.6 5.4e-15 55.5 0.4 1.5 1 0 0 1 1 1 1 HMG-box domain SAM_1 PF00536.25 AEO53511.1 - 1.7e-11 44.0 0.0 3.2e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 AEO53511.1 - 2.1e-09 37.0 0.0 5.8e-09 35.6 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) FbpA PF05833.6 AEO53511.1 - 0.1 11.0 0.4 0.15 10.5 0.3 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Cnd2 PF05786.9 AEO53513.1 - 1.9e-211 704.4 7.4 3e-211 703.7 5.1 1.2 1 0 0 1 1 1 1 Condensin complex subunit 2 Na_Ca_ex PF01699.19 AEO53514.1 - 2.1e-45 153.7 35.7 2.8e-25 88.5 9.2 3.3 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Herpes_gE PF02480.11 AEO53514.1 - 0.36 9.0 0.0 2.4 6.3 0.0 2.4 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E Osteopontin PF00865.13 AEO53514.1 - 3.9 6.6 6.1 6.2 5.9 4.2 1.2 1 0 0 1 1 1 0 Osteopontin PMM PF03332.8 AEO53515.1 - 1.6e-104 348.2 0.1 1.9e-104 348.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 AEO53515.1 - 0.014 14.9 0.0 0.14 11.6 0.0 2.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase TMPIT PF07851.8 AEO53515.1 - 0.038 13.0 0.1 0.052 12.6 0.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein Pico_P1A PF02226.11 AEO53515.1 - 0.16 11.7 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Picornavirus coat protein (VP4) WW PF00397.21 AEO53516.1 - 1e-09 38.0 0.1 3.2e-09 36.4 0.1 2.0 1 0 0 1 1 1 1 WW domain PhoD PF09423.5 AEO53516.1 - 0.054 12.0 1.9 0.14 10.6 0.6 1.9 2 0 0 2 2 2 0 PhoD-like phosphatase Tmemb_cc2 PF10267.4 AEO53516.1 - 0.4 9.2 0.2 0.73 8.3 0.1 1.3 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein MFS_1 PF07690.11 AEO53517.1 - 1.2e-05 24.1 25.2 2.5e-05 23.1 15.5 2.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Hist_deacetyl PF00850.14 AEO53518.1 - 4e-81 272.6 0.1 5.8e-81 272.1 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain ING PF12998.2 AEO53519.1 - 8.4e-23 80.6 8.2 1.3e-22 80.0 5.7 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 AEO53519.1 - 7.8e-08 31.8 9.6 1.2e-07 31.2 6.7 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 AEO53519.1 - 0.014 15.5 0.1 0.03 14.4 0.1 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain DivIC PF04977.10 AEO53519.1 - 1.1 8.7 5.1 6.1 6.4 0.5 2.4 2 0 0 2 2 2 0 Septum formation initiator UDPGP PF01704.13 AEO53520.1 - 2.9e-184 612.4 0.0 3.4e-184 612.2 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF3605 PF12239.3 AEO53521.1 - 1.5e-56 190.6 0.5 1.8e-56 190.3 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Glyco_hydro_7 PF00840.15 AEO53522.1 - 5.6e-203 674.1 17.8 6.5e-203 673.9 12.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Reo_sigmaC PF04582.7 AEO53523.1 - 0.15 11.1 4.1 0.28 10.3 2.9 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein RhoGEF PF00621.15 AEO53525.1 - 1.3e-34 119.6 0.0 2.1e-34 118.9 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain Velvet PF11754.3 AEO53526.1 - 4.6e-74 248.4 0.0 6.4e-74 247.9 0.0 1.1 1 0 0 1 1 1 1 Velvet factor DUF3602 PF12223.3 AEO53527.1 - 1.1e-16 61.0 12.9 3.1e-13 49.9 1.5 2.9 2 1 1 3 3 3 2 Protein of unknown function (DUF3602) TT_ORF2 PF02957.10 AEO53527.1 - 1.3 9.7 9.1 5.6 7.6 3.5 2.1 2 0 0 2 2 2 0 TT viral ORF2 PBP1_TM PF14812.1 AEO53527.1 - 4.4 7.6 8.5 1.7 9.0 3.6 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TFIIE-A_C-term PF11521.3 AEO53527.1 - 7.1 6.6 6.9 13 5.7 4.8 1.4 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha URO-D PF01208.12 AEO53528.1 - 8.9e-125 416.1 0.0 1e-124 415.9 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) PP1 PF07430.6 AEO53528.1 - 0.078 12.5 0.1 0.19 11.3 0.0 1.6 2 0 0 2 2 2 0 Phloem filament protein PP1 Zn_clus PF00172.13 AEO53530.1 - 3.7e-08 33.1 9.0 7.3e-08 32.1 6.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MBOAT_2 PF13813.1 AEO53531.1 - 7.6e-12 45.1 13.5 7.5e-11 41.9 9.3 2.6 1 1 0 1 1 1 1 Membrane bound O-acyl transferase family Zip PF02535.17 AEO53531.1 - 0.46 9.4 9.8 0.97 8.3 6.8 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Innate_immun PF12782.2 AEO53531.1 - 1.8 7.7 12.6 2.6 7.1 8.7 1.1 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family Aminotran_5 PF00266.14 AEO53532.1 - 3e-24 85.4 0.0 5.5e-24 84.5 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V MOSC_N PF03476.11 AEO53532.1 - 2.1e-22 79.0 0.0 6.2e-22 77.5 0.0 1.9 2 0 0 2 2 2 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 AEO53532.1 - 7.9e-19 67.4 0.0 1.8e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 MOSC domain AAA_16 PF13191.1 AEO53533.1 - 7.8e-14 52.0 1.2 4.6e-13 49.5 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 AEO53533.1 - 1.3e-10 41.5 0.0 3.3e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 AEO53533.1 - 2e-08 34.5 0.0 4.9e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Cdc6_C PF09079.6 AEO53533.1 - 0.00014 21.5 0.3 0.00056 19.5 0.0 2.2 3 0 0 3 3 2 1 CDC6, C terminal NACHT PF05729.7 AEO53533.1 - 0.00047 19.8 0.0 0.0011 18.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.1 AEO53533.1 - 0.0027 17.3 0.0 0.01 15.5 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 AEO53533.1 - 0.0031 17.6 0.0 0.006 16.7 0.0 1.4 1 0 0 1 1 1 1 RNA helicase Arch_ATPase PF01637.13 AEO53533.1 - 0.0036 17.0 0.0 0.016 14.9 0.0 1.9 1 1 0 1 1 1 1 Archaeal ATPase MMR_HSR1 PF01926.18 AEO53533.1 - 0.0047 16.8 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 AEO53533.1 - 0.0061 15.6 0.2 0.028 13.5 0.0 1.9 2 0 0 2 2 2 1 AIG1 family T2SE PF00437.15 AEO53533.1 - 0.015 14.1 0.0 0.031 13.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_32 PF13654.1 AEO53533.1 - 0.016 13.9 0.0 0.024 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 AEO53533.1 - 0.035 13.7 0.0 0.1 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 AEO53533.1 - 0.035 12.9 0.0 0.054 12.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF815 PF05673.8 AEO53533.1 - 0.041 12.8 0.0 0.076 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.1 AEO53533.1 - 0.044 13.6 0.0 0.084 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.9 AEO53533.1 - 0.046 12.6 0.3 0.079 11.8 0.0 1.5 2 0 0 2 2 1 0 PIF1-like helicase KAP_NTPase PF07693.9 AEO53533.1 - 0.049 12.6 0.0 0.079 11.9 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain ABC_tran PF00005.22 AEO53533.1 - 0.069 13.4 0.3 0.51 10.6 0.0 2.2 2 0 0 2 2 2 0 ABC transporter NTPase_1 PF03266.10 AEO53533.1 - 0.078 12.6 0.0 0.22 11.1 0.0 1.7 2 0 0 2 2 2 0 NTPase Miro PF08477.8 AEO53533.1 - 0.082 13.4 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein AAA_17 PF13207.1 AEO53533.1 - 0.12 13.1 0.0 0.25 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Aldedh PF00171.17 AEO53534.1 - 8.8e-134 446.3 0.1 1.1e-133 445.9 0.1 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Calreticulin PF00262.13 AEO53535.1 - 1.9e-162 540.0 17.7 2.7e-162 539.5 12.2 1.2 1 0 0 1 1 1 1 Calreticulin family OAD_gamma PF04277.8 AEO53535.1 - 2.3 8.6 8.4 0.55 10.6 0.2 3.2 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Aldolase_II PF00596.16 AEO53536.1 - 9.8e-41 139.3 0.0 1.2e-40 139.0 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF2457 PF10446.4 AEO53537.1 - 0.5 9.0 2.7 0.61 8.7 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Fer4_3 PF12798.2 AEO53537.1 - 1.2 9.8 8.4 0.88 10.2 0.3 3.2 3 1 0 3 3 3 0 4Fe-4S binding domain CobT PF06213.7 AEO53537.1 - 2.5 7.1 5.7 13 4.8 3.9 1.9 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Sld5 PF05916.6 AEO53538.1 - 1e-10 41.8 0.4 2.1e-10 40.8 0.2 1.5 1 0 0 1 1 1 1 GINS complex protein Arrestin_N PF00339.24 AEO53540.1 - 1.4e-16 60.6 0.0 2.9e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain F-box-like PF12937.2 AEO53541.1 - 0.00012 21.7 1.8 0.00029 20.4 1.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 AEO53541.1 - 0.012 15.3 0.8 0.025 14.2 0.6 1.5 1 0 0 1 1 1 0 F-box domain FAD_binding_3 PF01494.14 AEO53542.1 - 9.5e-54 182.7 0.0 1.2e-53 182.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 AEO53542.1 - 2.5e-33 115.0 0.0 5e-33 114.1 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Indigoidine_A PF04227.7 AEO53543.1 - 6.5e-107 357.1 0.2 8.9e-107 356.6 0.2 1.2 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 AEO53543.1 - 1.1e-16 60.8 0.1 1.4e-14 53.9 0.0 3.1 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Ins_P5_2-kin PF06090.7 AEO53543.1 - 0.082 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Inositol-pentakisphosphate 2-kinase WD40 PF00400.27 AEO53545.1 - 1.2e-09 37.7 6.8 0.018 14.8 0.0 6.0 7 0 0 7 7 7 3 WD domain, G-beta repeat DUF2583 PF10762.4 AEO53545.1 - 0.022 14.8 0.9 0.048 13.8 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2583) TruB_C PF09142.6 AEO53545.1 - 0.72 9.5 4.0 1.6 8.4 0.0 3.4 5 0 0 5 5 5 0 tRNA Pseudouridine synthase II, C terminal Sec20 PF03908.8 AEO53548.1 - 5.5e-14 51.6 1.6 7.6e-14 51.1 0.0 2.1 3 0 0 3 3 3 1 Sec20 Exonuc_VII_L PF02601.10 AEO53548.1 - 0.11 11.6 2.7 0.21 10.7 1.8 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit Fmp27_WPPW PF10359.4 AEO53548.1 - 7.1 4.9 9.2 1 7.6 1.7 2.1 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain MRP_L53 PF10780.4 AEO53549.1 - 1.1e-21 76.5 0.5 1.9e-21 75.7 0.3 1.4 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Mg-por_mtran_C PF07109.6 AEO53549.1 - 0.14 12.2 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Magnesium-protoporphyrin IX methyltransferase C-terminus Pyrophosphatase PF00719.14 AEO53550.1 - 3.5e-52 175.9 0.1 4.5e-52 175.6 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Membr_traf_MHD PF10540.4 AEO53551.1 - 1.9e-23 82.8 0.1 5.6e-23 81.2 0.1 1.9 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 AEO53551.1 - 1.7e-18 66.2 0.0 3.5e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 C2 domain ArfGap PF01412.13 AEO53552.1 - 9.8e-34 115.6 1.5 2.6e-33 114.2 0.0 2.4 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.24 AEO53552.1 - 2.2e-12 47.0 0.1 7.3e-12 45.4 0.0 1.9 1 0 0 1 1 1 1 PH domain PilJ PF13675.1 AEO53552.1 - 0.014 15.6 0.4 0.014 15.6 0.3 2.9 2 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term EMP24_GP25L PF01105.19 AEO53552.1 - 0.021 14.5 2.0 1.1 8.9 1.1 2.5 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD PH_9 PF15410.1 AEO53552.1 - 0.62 10.2 4.9 0.59 10.3 0.6 2.9 2 1 0 2 2 2 0 Pleckstrin homology domain Pkinase PF00069.20 AEO53553.1 - 2e-72 243.4 0.0 3.3e-72 242.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO53553.1 - 5.1e-36 124.0 0.0 7e-36 123.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 AEO53553.1 - 5.8e-18 64.7 0.4 1.2e-17 63.8 0.3 1.5 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 AEO53553.1 - 1.4e-09 37.3 0.0 7.6e-09 34.9 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 AEO53553.1 - 0.016 14.2 0.1 0.056 12.5 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 AEO53553.1 - 0.031 13.0 0.0 0.05 12.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PCI PF01399.22 AEO53554.1 - 4.5e-15 55.8 0.3 9.1e-14 51.6 0.1 2.5 2 0 0 2 2 2 1 PCI domain Bac_luciferase PF00296.15 AEO53554.1 - 0.026 13.6 0.0 0.11 11.5 0.0 2.0 2 0 0 2 2 2 0 Luciferase-like monooxygenase BCAS2 PF05700.6 AEO53554.1 - 0.032 13.6 1.2 0.063 12.7 0.8 1.4 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) ADK PF00406.17 AEO53555.1 - 4.2e-45 153.2 0.0 5.2e-45 153.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.1 AEO53555.1 - 3e-07 31.2 0.0 4.9e-07 30.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AEO53555.1 - 2.2e-06 27.9 0.0 3.4e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AEO53555.1 - 5.1e-06 26.4 0.1 1.5e-05 24.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 AEO53555.1 - 1.6e-05 24.3 0.1 0.006 15.9 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase PAS_7 PF12860.2 AEO53555.1 - 0.083 12.8 0.0 0.71 9.9 0.0 2.0 2 0 0 2 2 2 0 PAS fold MARVEL PF01284.18 AEO53556.1 - 0.005 16.6 6.4 0.005 16.6 4.5 1.9 1 1 1 2 2 2 1 Membrane-associating domain DUF202 PF02656.10 AEO53556.1 - 0.018 15.2 3.7 0.44 10.7 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF202) DUF3329 PF11808.3 AEO53556.1 - 0.045 13.8 0.2 1.3 9.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3329) GTP_EFTU PF00009.22 AEO53558.1 - 6.5e-38 130.0 0.0 1.1e-37 129.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 AEO53558.1 - 2.5e-37 126.7 0.3 5.1e-37 125.8 0.2 1.5 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 AEO53558.1 - 8.3e-10 38.6 0.1 1.8e-09 37.5 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 AEO53558.1 - 0.0084 16.0 0.0 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Nsp1_C PF05064.8 AEO53560.1 - 7.6e-41 138.4 3.4 7.6e-41 138.4 2.3 1.6 2 0 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 AEO53560.1 - 2.4e-16 59.9 246.0 0.00011 22.4 35.4 6.6 1 1 5 6 6 6 5 Nucleoporin FG repeat region Apolipoprotein PF01442.13 AEO53560.1 - 0.039 13.4 4.0 0.058 12.8 2.7 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Myosin_tail_1 PF01576.14 AEO53560.1 - 0.098 10.3 10.4 0.35 8.5 7.2 1.6 1 1 0 1 1 1 0 Myosin tail Spc7 PF08317.6 AEO53560.1 - 0.15 10.6 7.1 1.6 7.2 0.3 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein AAA_13 PF13166.1 AEO53560.1 - 0.23 9.9 4.1 0.38 9.1 2.8 1.3 1 0 0 1 1 1 0 AAA domain IncA PF04156.9 AEO53560.1 - 0.49 9.9 3.7 1.1 8.8 2.5 1.6 1 1 0 1 1 1 0 IncA protein MscS_porin PF12795.2 AEO53560.1 - 0.79 8.9 8.7 3.8 6.7 1.9 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF972 PF06156.8 AEO53560.1 - 0.94 9.8 2.8 4.1 7.8 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF972) DUF4200 PF13863.1 AEO53560.1 - 1.3 8.9 9.5 1.1 9.1 3.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) TPR_MLP1_2 PF07926.7 AEO53560.1 - 1.7 8.4 11.6 0.78 9.4 5.2 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein APG6 PF04111.7 AEO53560.1 - 8.1 5.3 10.0 69 2.3 0.1 1.9 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF577 PF04510.7 AEO53561.1 - 0.054 13.1 0.1 0.063 12.9 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF577) DUF3786 PF12654.2 AEO53562.1 - 0.078 12.2 0.1 0.096 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3786) adh_short PF00106.20 AEO53564.1 - 3.1e-29 102.0 7.9 4.3e-29 101.5 5.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO53564.1 - 1.1e-21 77.6 0.2 1.7e-21 77.1 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO53564.1 - 4.3e-13 49.3 3.3 9e-13 48.2 2.3 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 AEO53564.1 - 0.001 18.5 0.5 0.0021 17.5 0.4 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 AEO53564.1 - 0.035 12.8 0.0 0.05 12.2 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TAT_ubiq PF07706.7 AEO53564.1 - 0.13 12.2 0.3 21 5.1 0.0 2.6 2 0 0 2 2 2 0 Aminotransferase ubiquitination site NAD_binding_10 PF13460.1 AEO53564.1 - 0.13 12.2 3.2 0.56 10.1 2.2 2.0 1 1 0 1 1 1 0 NADH(P)-binding Rieske PF00355.21 AEO53566.1 - 5.4e-09 35.5 0.0 1.3e-08 34.3 0.0 1.6 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 AEO53566.1 - 9.3e-06 25.3 0.0 1.5e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Abhydrolase_5 PF12695.2 AEO53568.1 - 2.4e-07 30.6 0.2 3.4e-07 30.1 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Alpha-L-AF_C PF06964.7 AEO53569.1 - 2e-42 144.9 0.0 7.3e-42 143.1 0.0 1.9 1 1 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus CBM_4_9 PF02018.12 AEO53569.1 - 8.2e-05 22.6 0.6 0.00017 21.6 0.4 1.5 1 0 0 1 1 1 1 Carbohydrate binding domain 14-3-3 PF00244.15 AEO53570.1 - 5.3e-116 385.7 2.5 6e-116 385.5 1.7 1.0 1 0 0 1 1 1 1 14-3-3 protein zf-CSL PF05207.8 AEO53571.1 - 1.2e-15 56.6 0.5 1.8e-15 56.1 0.3 1.2 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.26 AEO53571.1 - 5.3e-14 51.6 0.1 8.7e-14 51.0 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain TT_ORF2 PF02957.10 AEO53571.1 - 0.2 12.3 0.1 0.2 12.3 0.0 2.7 3 0 0 3 3 3 0 TT viral ORF2 DEAD PF00270.24 AEO53573.1 - 3.1e-41 140.6 0.0 2.3e-40 137.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO53573.1 - 8.3e-25 86.4 0.0 1.7e-24 85.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3334 PF11813.3 AEO53573.1 - 0.0032 17.0 0.7 0.029 13.9 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3334) ResIII PF04851.10 AEO53573.1 - 0.029 14.2 0.0 0.11 12.2 0.0 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit RNA_pol_Rpc4 PF05132.9 AEO53573.1 - 0.14 12.1 0.5 0.64 10.0 0.4 2.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 CMS1 PF14617.1 AEO53573.1 - 1.7 7.6 0.0 1.7 7.6 0.0 2.9 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit Mito_carr PF00153.22 AEO53574.1 - 4.2e-60 199.4 0.2 2.3e-20 72.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serglycin PF04360.7 AEO53574.1 - 0.13 11.9 1.9 0.22 11.2 1.3 1.3 1 0 0 1 1 1 0 Serglycin TspO_MBR PF03073.10 AEO53575.1 - 3e-33 114.4 10.4 7.9e-33 113.0 6.8 1.9 1 1 1 2 2 2 1 TspO/MBR family DUF3546 PF12066.3 AEO53576.1 - 3.3e-25 88.2 2.4 3.3e-25 88.2 1.6 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3546) DUF4187 PF13821.1 AEO53576.1 - 3.3e-23 81.0 0.1 9.9e-23 79.4 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) ARS2 PF04959.8 AEO53576.1 - 3.8e-12 46.8 1.3 9.7e-12 45.5 0.9 1.7 1 0 0 1 1 1 1 Arsenite-resistance protein 2 Cpn60_TCP1 PF00118.19 AEO53577.1 - 1.9e-138 462.1 14.9 2.4e-138 461.8 10.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_tail_X PF05489.7 AEO53577.1 - 0.026 13.9 0.0 0.073 12.5 0.0 1.7 1 0 0 1 1 1 0 Phage Tail Protein X AAA PF00004.24 AEO53578.1 - 1.5e-40 138.4 0.0 2.5e-40 137.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AEO53578.1 - 4.5e-06 26.8 0.0 0.00059 19.9 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 AEO53578.1 - 2.2e-05 24.1 0.1 0.00024 20.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 AEO53578.1 - 0.00019 21.3 0.0 0.00071 19.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 AEO53578.1 - 0.00027 21.0 0.1 0.001 19.0 0.0 2.0 2 1 0 2 2 1 1 AAA ATPase domain DUF815 PF05673.8 AEO53578.1 - 0.0026 16.7 0.0 0.0045 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 AEO53578.1 - 0.0044 17.8 0.1 0.013 16.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 AEO53578.1 - 0.0087 15.1 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 AEO53578.1 - 0.0095 15.6 0.2 0.022 14.5 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 AEO53578.1 - 0.018 14.9 0.0 0.045 13.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 AEO53578.1 - 0.026 14.4 0.0 0.055 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 AEO53578.1 - 0.03 13.9 0.0 0.62 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 AEO53578.1 - 0.035 13.9 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 AEO53578.1 - 0.045 13.9 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.6 AEO53578.1 - 0.061 12.9 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 AEO53578.1 - 0.067 13.2 0.0 0.19 11.7 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.7 AEO53578.1 - 0.08 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.12 AEO53578.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Arch_ATPase PF01637.13 AEO53578.1 - 0.12 12.0 0.2 11 5.6 0.0 2.5 2 1 1 3 3 3 0 Archaeal ATPase IBR PF01485.16 AEO53579.1 - 3.3 7.6 12.0 0.9 9.4 3.1 2.5 2 0 0 2 2 2 0 IBR domain zf-C3HC4 PF00097.20 AEO53579.1 - 8.3 6.1 13.6 1.9 8.2 3.8 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.17 AEO53580.1 - 1.3e-18 66.3 0.3 4.7e-18 64.5 0.1 1.8 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO53580.1 - 1.7e-12 47.1 0.0 2.7e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO53580.1 - 3.6e-10 39.5 0.1 5.8e-10 38.8 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3661 PF12400.3 AEO53581.1 - 4.8e-42 143.0 3.5 6.7e-42 142.6 2.4 1.2 1 0 0 1 1 1 1 Vaculolar membrane protein Tyrosinase PF00264.15 AEO53582.1 - 8.7e-55 186.2 0.6 1.3e-54 185.7 0.4 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase RNA_pol_Rpb2_6 PF00562.23 AEO53583.1 - 9.1e-114 380.1 0.0 1.1e-113 379.8 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 AEO53583.1 - 2.9e-28 98.1 0.0 4.3e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 AEO53583.1 - 1.8e-25 89.4 0.0 3.4e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 AEO53583.1 - 2e-25 88.2 0.0 5.8e-25 86.8 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.7 AEO53583.1 - 1.5e-24 85.7 0.0 3.5e-24 84.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.15 AEO53583.1 - 1.4e-14 54.0 0.0 6e-14 52.0 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 AEO53583.1 - 3.6e-05 23.6 0.1 9.2e-05 22.3 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Arf PF00025.16 AEO53584.1 - 2.1e-30 105.2 0.0 2.3e-30 105.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 AEO53584.1 - 1.6e-12 47.1 0.0 1.9e-12 46.8 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 AEO53584.1 - 5e-06 25.4 0.0 1.1e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 G-protein alpha subunit Gtr1_RagA PF04670.7 AEO53584.1 - 0.0003 19.9 0.0 0.00034 19.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 AEO53584.1 - 0.00032 21.1 0.0 0.00085 19.8 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 AEO53584.1 - 0.0029 17.0 0.0 0.0033 16.8 0.0 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Ribosomal_S9 PF00380.14 AEO53585.1 - 4.7e-38 130.1 0.3 5.4e-38 129.9 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 RCR PF12273.3 AEO53586.1 - 5.4e-26 91.6 7.8 7e-26 91.3 5.4 1.1 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red WBP-1 PF11669.3 AEO53586.1 - 0.073 13.1 0.8 0.073 13.1 0.6 2.6 2 1 1 3 3 3 0 WW domain-binding protein 1 DUF4131 PF13567.1 AEO53586.1 - 0.47 9.8 2.6 0.72 9.2 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Ribosomal_L19 PF01245.15 AEO53588.1 - 0.22 11.3 0.0 0.36 10.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L19 Vps39_2 PF10367.4 AEO53589.1 - 0.43 10.7 4.3 0.92 9.7 3.0 1.4 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 Ppx-GppA PF02541.11 AEO53590.1 - 1.2e-28 100.1 0.0 3.1e-27 95.4 0.0 2.1 1 1 0 1 1 1 1 Ppx/GppA phosphatase family Per1 PF04080.8 AEO53592.1 - 1.2e-100 336.4 6.1 1.6e-100 335.9 4.2 1.1 1 0 0 1 1 1 1 Per1-like Acetyltransf_3 PF13302.1 AEO53593.1 - 8.5e-31 107.0 0.0 1e-30 106.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 AEO53593.1 - 5.2e-10 39.4 0.0 6.7e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 AEO53593.1 - 1.9e-09 37.4 0.0 2.9e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 AEO53593.1 - 4.4e-06 26.6 0.0 1.7e-05 24.7 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain COPIIcoated_ERV PF07970.7 AEO53594.1 - 9.6e-73 244.4 0.0 3.9e-71 239.2 0.0 2.2 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 AEO53594.1 - 2.8e-35 120.1 0.0 5.7e-35 119.1 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) FAD_binding_2 PF00890.19 AEO53595.1 - 2e-85 287.1 1.3 2.9e-85 286.6 0.9 1.2 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 AEO53595.1 - 4.9e-22 77.5 0.2 1.8e-20 72.5 0.0 3.1 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 AEO53595.1 - 2.8e-14 52.7 2.0 1.2e-13 50.7 1.4 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 AEO53595.1 - 4.2e-10 39.2 0.4 1.6e-09 37.4 0.3 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AEO53595.1 - 4.9e-09 36.0 2.5 5.6e-08 32.7 0.3 3.0 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 AEO53595.1 - 5.1e-09 36.3 0.0 4.3e-07 30.0 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 AEO53595.1 - 7.5e-07 27.9 2.1 0.0042 15.6 0.2 3.3 3 0 0 3 3 3 3 HI0933-like protein Thi4 PF01946.12 AEO53595.1 - 8.7e-05 21.7 2.4 0.018 14.1 0.7 2.7 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.14 AEO53595.1 - 0.00017 20.7 2.8 0.00046 19.3 1.9 1.7 1 1 0 1 1 1 1 FAD binding domain GIDA PF01134.17 AEO53595.1 - 0.00044 19.2 2.4 0.096 11.5 0.5 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A Amino_oxidase PF01593.19 AEO53595.1 - 0.0012 18.0 1.2 0.053 12.5 0.1 2.8 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 AEO53595.1 - 0.0021 17.8 0.6 0.015 15.0 0.3 2.5 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 AEO53595.1 - 0.026 14.9 3.0 0.17 12.3 0.6 2.9 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AEO53595.1 - 0.061 13.3 0.8 0.23 11.5 0.6 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Sel1 PF08238.7 AEO53596.1 - 1.2e-15 57.5 10.2 0.00024 21.6 0.0 4.4 4 0 0 4 4 4 3 Sel1 repeat Proteasome PF00227.21 AEO53597.1 - 2.4e-46 157.4 0.1 3.1e-46 157.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 AEO53597.1 - 3.9e-13 48.4 0.0 8.2e-13 47.3 0.0 1.5 1 0 0 1 1 1 1 Proteasome beta subunits C terminal ER_lumen_recept PF00810.13 AEO53599.1 - 1.8e-37 129.0 10.9 2.6e-37 128.5 7.5 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor DUF2227 PF09988.4 AEO53599.1 - 0.063 12.9 1.3 0.12 12.0 0.9 1.4 1 0 0 1 1 1 0 Uncharacterized metal-binding protein (DUF2227) PQ-loop PF04193.9 AEO53599.1 - 0.063 12.8 1.7 0.42 10.2 0.1 2.8 2 0 0 2 2 2 0 PQ loop repeat Nop14 PF04147.7 AEO53599.1 - 0.093 10.6 8.2 0.12 10.2 5.7 1.1 1 0 0 1 1 1 0 Nop14-like family Orbi_NS3 PF01616.11 AEO53600.1 - 0.031 13.2 3.8 0.056 12.3 2.6 1.4 1 0 0 1 1 1 0 Orbivirus NS3 Cmc1 PF08583.5 AEO53601.1 - 0.001 18.8 0.8 0.0041 16.8 0.5 2.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Tmemb_cc2 PF10267.4 AEO53601.1 - 0.045 12.3 4.8 0.018 13.6 1.6 1.5 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein MARCKS PF02063.12 AEO53602.1 - 3.6 7.3 22.1 5.3 6.8 15.3 1.3 1 0 0 1 1 1 0 MARCKS family LRR_6 PF13516.1 AEO53603.1 - 1.3e-12 46.4 6.4 0.013 15.4 0.0 6.7 6 0 0 6 6 6 3 Leucine Rich repeat LRR_4 PF12799.2 AEO53603.1 - 9.9e-11 41.0 10.4 0.00019 20.9 0.0 5.9 5 2 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 AEO53603.1 - 5.6e-07 28.7 3.8 6 7.3 0.0 5.8 7 0 0 7 7 7 3 Leucine Rich Repeat LRR_7 PF13504.1 AEO53603.1 - 0.0013 18.5 7.0 8 7.1 0.0 5.3 5 0 0 5 5 5 1 Leucine rich repeat LRR_8 PF13855.1 AEO53603.1 - 0.0015 18.1 10.4 0.4 10.4 0.1 4.5 3 2 0 3 3 3 1 Leucine rich repeat LETM1 PF07766.8 AEO53603.1 - 0.0088 15.1 0.3 0.043 12.8 0.0 2.1 2 0 0 2 2 2 1 LETM1-like protein Spore_coat_CotO PF14153.1 AEO53603.1 - 8.5 5.7 13.8 14 5.0 9.6 1.3 1 0 0 1 1 1 0 Spore coat protein CotO zf-H2C2_2 PF13465.1 AEO53604.1 - 2.6e-07 30.6 9.0 3.4e-06 27.0 0.7 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 AEO53604.1 - 2.7e-05 24.1 4.2 0.00058 20.0 0.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 AEO53604.1 - 0.00018 21.6 0.3 0.00018 21.6 0.2 3.4 3 1 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 AEO53604.1 - 0.4 10.8 3.8 4.2 7.6 0.3 2.9 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF3995 PF13160.1 AEO53605.1 - 0.0027 17.7 1.6 0.0035 17.3 0.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3995) DUF998 PF06197.8 AEO53605.1 - 1.7 7.8 12.2 0.2 10.9 4.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF998) Fe_hyd_lg_C PF02906.9 AEO53606.1 - 2e-60 204.5 0.0 4.4e-60 203.3 0.0 1.6 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain SUZ PF12752.2 AEO53607.1 - 2.6e-06 27.8 3.5 2.6e-06 27.8 2.4 4.1 4 1 0 4 4 4 1 SUZ domain Ycf1 PF05758.7 AEO53607.1 - 0.2 9.3 1.2 0.27 8.8 0.8 1.1 1 0 0 1 1 1 0 Ycf1 DUF4407 PF14362.1 AEO53607.1 - 0.43 9.5 3.4 0.64 8.9 2.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Paf1 PF03985.8 AEO53607.1 - 2.4 6.7 11.7 0.1 11.3 2.0 2.0 2 0 0 2 2 2 0 Paf1 DUF1754 PF08555.5 AEO53607.1 - 2.6 8.6 16.2 3.9 8.1 3.9 3.2 3 0 0 3 3 3 0 Eukaryotic family of unknown function (DUF1754) Pkinase PF00069.20 AEO53609.1 - 3.8e-71 239.3 0.0 5.2e-71 238.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO53609.1 - 3.3e-31 108.2 0.0 4.8e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 AEO53609.1 - 5e-14 52.5 1.4 5e-14 52.5 1.0 2.0 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 AEO53609.1 - 2.3e-09 36.6 0.0 4.4e-09 35.7 0.0 1.5 2 0 0 2 2 2 1 Kinase-like C2 PF00168.25 AEO53609.1 - 0.00033 20.4 0.0 0.0013 18.5 0.0 2.0 1 1 0 1 1 1 1 C2 domain Kdo PF06293.9 AEO53609.1 - 0.014 14.4 0.0 0.025 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 AEO53609.1 - 0.03 13.6 0.0 0.07 12.4 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 AEO53609.1 - 0.044 13.5 0.0 0.08 12.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 AEO53609.1 - 0.056 13.0 0.1 0.098 12.2 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase ATP_sub_h PF10775.4 AEO53610.1 - 3.6e-26 90.6 0.8 5.3e-26 90.1 0.6 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h DOMON PF03351.12 AEO53611.1 - 4e-06 26.7 0.0 8.2e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 DOMON domain DUF2427 PF10348.4 AEO53611.1 - 7.1e-05 22.3 3.3 0.00016 21.2 2.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.11 AEO53611.1 - 0.00069 19.4 11.0 0.0015 18.3 7.6 1.6 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 Pkinase PF00069.20 AEO53612.1 - 2.2e-66 223.6 0.0 2.7e-66 223.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO53612.1 - 3e-30 105.1 0.0 3.9e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 AEO53612.1 - 0.0018 18.7 0.0 0.0063 17.0 0.0 2.0 1 1 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 AEO53612.1 - 0.0056 15.6 0.0 0.017 14.1 0.0 1.7 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 AEO53612.1 - 0.047 13.4 0.4 0.66 9.6 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family WD40 PF00400.27 AEO53613.1 - 1.9e-50 167.0 16.9 4.8e-10 38.9 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 AEO53613.1 - 1.3e-15 56.3 2.4 2.2e-15 55.6 1.6 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Nbas_N PF15492.1 AEO53613.1 - 0.022 13.8 0.2 1.1 8.3 0.0 2.7 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal eIF2A PF08662.6 AEO53613.1 - 0.052 13.2 0.0 1.7 8.2 0.0 3.0 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A Ribosomal_60s PF00428.14 AEO53613.1 - 2.2 8.7 13.5 4.9 7.6 9.4 1.5 1 1 0 1 1 1 0 60s Acidic ribosomal protein Cyclin_N PF00134.18 AEO53614.1 - 1.2e-10 40.9 0.1 2.4e-10 40.0 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Dus PF01207.12 AEO53615.1 - 3.5e-26 91.7 0.0 4e-22 78.4 0.0 2.4 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) Mucin PF01456.12 AEO53615.1 - 0.026 14.2 8.0 0.043 13.6 5.6 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein AIRC PF00731.15 AEO53616.1 - 9.5e-60 200.2 0.1 1.9e-59 199.2 0.1 1.5 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 AEO53616.1 - 1.1e-48 164.7 0.0 2.1e-48 163.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 AEO53616.1 - 4.4e-11 42.8 0.0 1.1e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 AEO53616.1 - 6.5e-06 25.6 0.0 1.8e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus XdhC_C PF13478.1 AEO53616.1 - 0.00043 20.5 0.0 0.064 13.5 0.0 2.8 3 0 0 3 3 3 1 XdhC Rossmann domain CPSase_L_D2 PF02786.12 AEO53616.1 - 0.00064 19.0 0.0 0.12 11.6 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain 2-Hacid_dh_C PF02826.14 AEO53616.1 - 0.0015 17.6 0.0 0.0026 16.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PrpR_N PF06506.6 AEO53616.1 - 0.044 13.1 0.1 0.37 10.1 0.0 2.3 2 0 0 2 2 2 0 Propionate catabolism activator Dicty_REP PF05086.7 AEO53617.1 - 3.6 5.2 5.2 4.6 4.8 3.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3809 PF12723.2 AEO53618.1 - 0.056 13.3 0.2 0.14 11.9 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3809) Fer2_3 PF13085.1 AEO53619.1 - 4.4e-33 113.3 0.0 7.2e-33 112.6 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_8 PF13183.1 AEO53619.1 - 2.8e-09 36.8 4.6 2.8e-09 36.8 3.2 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_17 PF13534.1 AEO53619.1 - 3.3e-09 36.9 6.7 3.3e-09 36.9 4.6 2.1 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 AEO53619.1 - 3.2e-05 24.2 1.8 3.2e-05 24.2 1.2 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 AEO53619.1 - 8.1e-05 22.3 4.3 8.1e-05 22.3 3.0 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 AEO53619.1 - 0.00018 21.7 4.5 0.027 14.7 0.5 3.1 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer2 PF00111.22 AEO53619.1 - 0.0034 17.0 3.0 0.0041 16.8 0.2 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.2 AEO53619.1 - 0.014 15.7 5.8 0.014 15.7 4.0 2.4 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_15 PF13459.1 AEO53619.1 - 2.5 8.7 6.3 1 9.9 0.1 2.6 3 0 0 3 3 3 0 4Fe-4S single cluster domain Sel1 PF08238.7 AEO53621.1 - 1.9e-43 145.9 56.8 2.4e-07 31.1 0.5 11.7 11 1 1 12 12 12 9 Sel1 repeat Ctr PF04145.10 AEO53621.1 - 0.01 15.9 0.4 0.024 14.6 0.3 1.6 1 0 0 1 1 1 1 Ctr copper transporter family FHIPEP PF00771.15 AEO53621.1 - 0.13 10.5 1.0 0.19 10.0 0.7 1.1 1 0 0 1 1 1 0 FHIPEP family WD40 PF00400.27 AEO53622.1 - 1.3e-12 47.0 0.5 0.00079 19.2 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat Thiolase_N PF00108.18 AEO53623.1 - 3.1e-92 308.3 0.3 3.1e-92 308.3 0.2 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 AEO53623.1 - 1.7e-47 159.8 0.2 4.2e-47 158.6 0.2 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 AEO53623.1 - 0.00041 19.9 0.9 0.00041 19.9 0.6 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 AEO53623.1 - 0.056 13.0 3.5 0.72 9.5 0.0 2.9 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GTP_EFTU PF00009.22 AEO53624.1 - 7e-43 146.2 0.0 9.8e-43 145.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 AEO53624.1 - 1.2e-27 95.8 0.0 2.8e-27 94.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 AEO53624.1 - 2.2e-18 65.8 0.0 6.7e-18 64.3 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 AEO53624.1 - 3.5e-10 39.8 0.2 1e-09 38.3 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 AEO53624.1 - 2e-06 27.5 0.0 4.4e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 AEO53624.1 - 5.8e-06 26.2 0.1 1.1e-05 25.3 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 AEO53624.1 - 0.00091 19.7 0.0 0.0029 18.0 0.0 1.9 1 1 0 1 1 1 1 Miro-like protein HSP90 PF00183.13 AEO53624.1 - 0.094 11.0 0.0 0.15 10.3 0.0 1.2 1 0 0 1 1 1 0 Hsp90 protein DUF59 PF01883.14 AEO53625.1 - 1.3e-05 25.0 0.0 4.1e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function DUF59 Fungal_trans PF04082.13 AEO53626.1 - 8.9e-13 47.7 0.0 1.3e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO53626.1 - 3.5e-07 30.0 8.7 7.7e-07 28.9 6.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAH PF02671.16 AEO53628.1 - 3.2e-41 138.6 3.1 2e-17 62.5 0.6 3.5 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 AEO53628.1 - 3.3e-39 132.6 1.8 9.6e-39 131.2 0.0 2.5 2 0 0 2 2 2 1 Sin3 family co-repressor Sugar_tr PF00083.19 AEO53629.1 - 1.2e-125 419.6 21.8 1.4e-125 419.4 15.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO53629.1 - 4.1e-23 81.6 36.4 8.8e-17 60.8 8.3 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Alpha_L_fucos PF01120.12 AEO53629.1 - 0.05 12.5 1.3 0.075 11.9 0.9 1.1 1 0 0 1 1 1 0 Alpha-L-fucosidase Glyco_hydro_31 PF01055.21 AEO53630.1 - 2.2e-152 507.9 0.5 3e-152 507.5 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Rotavirus_VP7 PF05868.6 AEO53630.1 - 0.086 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Rotavirus major outer capsid protein VP7 DUF4448 PF14610.1 AEO53631.1 - 1e-41 142.4 0.0 1.4e-41 142.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DEC-1_N PF04625.8 AEO53631.1 - 9.8 4.7 13.5 3.9 6.0 4.4 2.1 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region FRG1 PF06229.7 AEO53633.1 - 1.9e-56 190.5 0.0 2.8e-56 190.0 0.0 1.2 1 0 0 1 1 1 1 FRG1-like family Fascin PF06268.8 AEO53633.1 - 0.017 15.2 0.0 0.046 13.8 0.0 1.7 2 0 0 2 2 2 0 Fascin domain SRF-TF PF00319.13 AEO53634.1 - 1.8e-22 78.3 0.1 2.6e-22 77.7 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) SLD3 PF08639.5 AEO53634.1 - 0.23 10.0 2.5 0.35 9.4 1.7 1.2 1 0 0 1 1 1 0 DNA replication regulator SLD3 DUF3591 PF12157.3 AEO53635.1 - 6.4e-187 621.5 0.0 9.6e-187 620.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC PF00098.18 AEO53635.1 - 0.015 15.2 0.9 0.026 14.4 0.6 1.4 1 0 0 1 1 1 0 Zinc knuckle OrfB_Zn_ribbon PF07282.6 AEO53635.1 - 0.046 13.3 0.5 0.1 12.2 0.3 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-CCHC_6 PF15288.1 AEO53635.1 - 0.11 12.2 4.0 0.25 11.0 2.8 1.6 1 0 0 1 1 1 0 Zinc knuckle D-ser_dehydrat PF14031.1 AEO53636.1 - 3.9e-24 84.6 0.0 8.7e-24 83.5 0.0 1.6 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 AEO53636.1 - 4.9e-13 49.1 0.0 7.9e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Actin PF00022.14 AEO53637.1 - 7.1e-142 472.4 0.0 8e-142 472.2 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 AEO53637.1 - 8.1e-05 21.3 0.0 0.088 11.3 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein PIG-P PF08510.7 AEO53638.1 - 6.3e-45 151.8 0.0 9.3e-45 151.3 0.0 1.2 1 0 0 1 1 1 1 PIG-P GRP PF07172.6 AEO53638.1 - 0.00037 20.9 6.1 0.00037 20.9 4.2 3.0 2 1 1 3 3 3 1 Glycine rich protein family CDC45 PF02724.9 AEO53638.1 - 0.18 9.7 0.0 0.2 9.6 0.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Vps8 PF12816.2 AEO53639.1 - 8.6e-75 250.2 0.0 1.6e-74 249.4 0.0 1.5 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 AEO53639.1 - 0.00012 21.6 0.2 0.072 12.6 0.0 3.5 3 0 0 3 3 3 1 Region in Clathrin and VPS zf-RING_2 PF13639.1 AEO53639.1 - 0.00025 20.7 0.0 0.0007 19.3 0.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 AEO53639.1 - 0.0017 18.3 0.0 0.0044 17.0 0.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO53639.1 - 0.005 16.5 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 AEO53639.1 - 0.0073 15.9 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 AEO53639.1 - 0.081 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger zf-Nse PF11789.3 AEO53639.1 - 0.29 10.6 0.0 0.57 9.7 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF3752 PF12572.3 AEO53640.1 - 6.4e-45 152.9 3.8 6.4e-45 152.9 2.6 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF3752) zf-RING_2 PF13639.1 AEO53641.1 - 1.1e-13 50.7 7.0 1.7e-13 50.1 4.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 AEO53641.1 - 1.3e-08 34.8 4.7 2.7e-08 33.8 3.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 AEO53641.1 - 5.3e-08 32.3 4.4 8.6e-08 31.7 3.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO53641.1 - 4.6e-06 26.2 4.1 7.2e-06 25.6 2.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 AEO53641.1 - 1.7e-05 24.7 5.9 2.6e-05 24.1 4.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AEO53641.1 - 5e-05 22.8 2.6 7.5e-05 22.3 1.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 AEO53641.1 - 0.00024 20.8 2.7 0.00061 19.5 1.9 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 AEO53641.1 - 0.0074 15.8 6.6 0.012 15.1 4.6 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 AEO53641.1 - 0.062 13.0 0.6 0.15 11.8 0.1 1.9 1 1 1 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 AEO53641.1 - 0.11 12.4 4.8 0.21 11.4 3.4 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PHD PF00628.24 AEO53641.1 - 0.19 11.4 5.7 0.34 10.6 3.9 1.4 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.3 AEO53641.1 - 0.25 11.3 3.8 0.8 9.7 2.6 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 AEO53641.1 - 0.7 9.9 5.8 1.6 8.8 4.0 1.6 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.1 AEO53641.1 - 2.5 7.9 9.0 0.15 11.8 1.2 2.1 1 1 0 2 2 2 0 Prokaryotic RING finger family 1 DUF2235 PF09994.4 AEO53642.1 - 2.5e-17 63.1 0.0 7e-17 61.6 0.0 1.7 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 AEO53642.1 - 0.1 12.3 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_M16 PF00675.15 AEO53643.1 - 9.8e-57 190.8 0.5 2.2e-56 189.7 0.4 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 AEO53643.1 - 1.9e-39 135.2 0.0 4.1e-38 130.9 0.0 2.2 2 0 0 2 2 2 1 Peptidase M16 inactive domain RbsD_FucU PF05025.8 AEO53643.1 - 0.069 13.4 0.4 0.35 11.1 0.1 2.1 2 0 0 2 2 2 0 RbsD / FucU transport protein family Raffinose_syn PF05691.7 AEO53645.1 - 4.6e-56 189.7 0.2 3.8e-49 166.9 0.2 3.0 2 1 0 2 2 2 2 Raffinose synthase or seed imbibition protein Sip1 Melibiase PF02065.13 AEO53645.1 - 3.9e-05 22.5 0.9 0.0001 21.1 0.6 1.5 1 1 0 1 1 1 1 Melibiase DUF1713 PF08213.6 AEO53646.1 - 2.2e-11 43.1 21.8 4e-11 42.3 15.1 1.5 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Thioredoxin_4 PF13462.1 AEO53647.1 - 1.2e-07 31.8 0.0 1.9e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.15 AEO53647.1 - 0.016 14.7 3.7 0.69 9.4 0.1 2.6 2 1 1 3 3 3 0 DSBA-like thioredoxin domain DUF4411 PF14367.1 AEO53647.1 - 0.091 12.4 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4411) SeqA PF03925.8 AEO53647.1 - 0.14 11.8 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 SeqA protein NGP1NT PF08153.7 AEO53648.1 - 3.9e-49 165.9 0.8 6.5e-49 165.1 0.6 1.4 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 AEO53648.1 - 1.2e-20 73.5 0.0 1.1e-16 60.7 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 AEO53648.1 - 1.9e-06 27.2 0.0 1.5e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 AEO53648.1 - 0.00015 20.9 0.0 0.00029 20.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 AEO53648.1 - 0.0036 17.1 8.9 0.11 12.3 0.0 4.0 3 2 1 4 4 4 1 Dynamin family GTP_EFTU PF00009.22 AEO53648.1 - 0.0085 15.5 0.0 1.1 8.7 0.0 3.1 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain Arf PF00025.16 AEO53648.1 - 0.021 14.0 0.0 2.5 7.2 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_16 PF13191.1 AEO53648.1 - 0.064 13.2 0.0 3.8 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain BUD22 PF09073.5 AEO53648.1 - 1.9 7.4 30.9 4.7 6.1 21.4 1.7 1 0 0 1 1 1 0 BUD22 TLP-20 PF06088.6 AEO53648.1 - 8.6 6.0 10.1 29 4.2 0.0 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) ABC2_membrane PF01061.19 AEO53650.1 - 2.5e-38 131.3 23.6 4.8e-38 130.4 16.3 1.5 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 AEO53650.1 - 3.3e-24 85.7 0.0 6.1e-24 84.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 AEO53650.1 - 2.7e-09 37.4 0.0 4.5e-08 33.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 AEO53650.1 - 2.7e-07 29.9 32.2 1.2e-06 27.8 22.3 2.0 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_25 PF13481.1 AEO53650.1 - 4.7e-05 22.8 0.0 0.0097 15.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain hEGF PF12661.2 AEO53650.1 - 0.00046 20.0 24.1 0.016 15.2 1.4 4.7 3 1 0 3 3 3 2 Human growth factor-like EGF AAA_15 PF13175.1 AEO53650.1 - 0.0026 16.8 0.0 1.3 7.9 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 AEO53650.1 - 0.0065 15.9 0.1 0.016 14.7 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 AEO53650.1 - 0.01 14.9 0.0 0.022 13.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_33 PF13671.1 AEO53650.1 - 0.025 14.4 0.0 0.059 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 AEO53650.1 - 0.026 14.8 0.0 0.067 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.14 AEO53650.1 - 0.042 13.0 0.0 0.51 9.5 0.0 2.2 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 AEO53650.1 - 0.049 13.6 0.0 0.092 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 AEO53650.1 - 0.055 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.1 AEO53650.1 - 0.07 13.4 0.3 0.12 12.7 0.2 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 AEO53650.1 - 0.07 13.2 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 AEO53650.1 - 0.071 13.9 0.0 0.15 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 AEO53650.1 - 0.095 12.6 0.0 0.34 10.8 0.0 2.0 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.1 AEO53650.1 - 0.16 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 AEO53650.1 - 0.22 11.4 0.0 0.43 10.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC2_membrane_2 PF12679.2 AEO53650.1 - 0.32 9.7 23.1 0.0069 15.2 6.2 2.3 1 1 0 2 2 2 0 ABC-2 family transporter protein Aminotran_1_2 PF00155.16 AEO53651.1 - 3.3e-36 125.0 0.0 4e-36 124.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 AEO53651.1 - 1.7e-05 23.7 0.0 2.6e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 AEO53651.1 - 3.9e-05 22.1 0.0 5.5e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 AEO53651.1 - 4.7e-05 22.6 0.0 7.2e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_MocR PF12897.2 AEO53651.1 - 0.023 13.2 0.0 0.033 12.7 0.0 1.3 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase Alliinase_C PF04864.8 AEO53651.1 - 0.024 13.3 0.0 0.039 12.6 0.0 1.3 1 0 0 1 1 1 0 Allinase Asp PF00026.18 AEO53652.1 - 4.6e-63 213.3 0.7 5.7e-63 213.0 0.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 AEO53652.1 - 5e-08 33.0 0.0 1.7e-06 28.0 0.0 3.1 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 AEO53652.1 - 0.018 15.4 0.2 8.3 6.9 0.1 3.3 2 1 0 2 2 2 0 Aspartyl protease gag-asp_proteas PF13975.1 AEO53652.1 - 0.032 14.0 0.0 8.4 6.3 0.0 2.6 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease TAXi_C PF14541.1 AEO53652.1 - 0.13 11.8 0.0 0.48 9.9 0.0 2.0 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal GTP_EFTU PF00009.22 AEO53653.1 - 9.4e-57 191.4 0.0 2.5e-56 190.0 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 AEO53653.1 - 4.9e-33 112.8 0.0 9.6e-33 111.8 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 AEO53653.1 - 2.3e-31 107.8 0.0 5.4e-31 106.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 AEO53653.1 - 1.6e-22 79.1 0.0 3.9e-22 77.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 AEO53653.1 - 4.4e-14 52.3 0.0 1.2e-13 50.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 DUF442 PF04273.8 AEO53653.1 - 0.04 13.7 0.1 4.7 7.1 0.0 3.3 3 0 0 3 3 3 0 Putative phosphatase (DUF442) Iso_dh PF00180.15 AEO53654.1 - 3e-97 325.6 0.0 4.5e-97 325.1 0.0 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Ribosomal_S8 PF00410.14 AEO53655.1 - 2.3e-28 98.6 0.0 2.7e-28 98.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 SPO11_like PF03533.9 AEO53655.1 - 0.00091 19.0 0.4 0.0017 18.2 0.3 1.4 1 0 0 1 1 1 1 SPO11 homologue Yae1_N PF09811.4 AEO53657.1 - 7.6e-13 47.7 1.2 7.6e-13 47.7 0.8 1.7 2 0 0 2 2 2 1 Essential protein Yae1, N terminal Trypsin_2 PF13365.1 AEO53658.1 - 0.00017 21.5 0.0 0.0004 20.3 0.0 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_C3 PF00548.15 AEO53658.1 - 0.0072 16.1 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 3C cysteine protease (picornain 3C) Peptidase_C4 PF00863.14 AEO53658.1 - 0.022 13.7 0.0 0.037 12.9 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C4 COPI_C PF06957.6 AEO53658.1 - 0.13 10.7 0.0 0.19 10.2 0.0 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Ank_2 PF12796.2 AEO53660.1 - 3.6e-16 59.2 1.2 2.2e-10 40.7 0.2 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 AEO53660.1 - 1.3e-15 56.3 0.9 0.00013 21.5 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 AEO53660.1 - 3.7e-15 55.5 0.2 3.1e-06 27.2 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 AEO53660.1 - 5.1e-13 49.1 1.7 6.4e-07 29.7 0.2 4.5 1 1 3 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 AEO53660.1 - 7.6e-10 38.0 0.2 0.17 12.2 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat vWA-TerF-like PF10138.4 AEO53660.1 - 0.011 15.6 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 vWA found in TerF C terminus PNP_UDP_1 PF01048.15 AEO53661.1 - 3.7e-13 48.9 0.2 3.7e-12 45.7 0.2 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily Flavodoxin_1 PF00258.20 AEO53662.1 - 2.9e-10 40.2 0.0 5.1e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin FMN_red PF03358.10 AEO53662.1 - 3.5e-08 33.0 0.0 5.1e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 AEO53662.1 - 1e-05 25.1 0.0 1.3e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.2 AEO53662.1 - 0.062 13.3 0.0 1.5 8.8 0.0 2.1 1 1 1 2 2 2 0 Flavodoxin domain MFS_1 PF07690.11 AEO53663.1 - 2e-19 69.5 55.2 2e-13 49.7 21.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Epiglycanin_C PF14654.1 AEO53664.1 - 0.11 12.5 0.0 0.67 9.9 0.0 2.2 3 0 0 3 3 3 0 Mucin, catalytic, TM and cytoplasmic tail region Zip PF02535.17 AEO53664.1 - 0.16 10.9 2.5 0.25 10.3 1.7 1.4 1 1 0 1 1 1 0 ZIP Zinc transporter Methyltransf_6 PF03737.10 AEO53665.1 - 6.4e-28 97.5 0.0 8.3e-28 97.1 0.0 1.2 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase Ferric_reduct PF01794.14 AEO53666.1 - 5.9e-18 65.1 17.0 5.9e-18 65.1 11.8 2.8 3 1 0 3 3 3 1 Ferric reductase like transmembrane component DUF4233 PF14017.1 AEO53666.1 - 4.2 7.3 22.1 0.028 14.3 6.6 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF4233) MFS_1 PF07690.11 AEO53667.1 - 4e-24 85.0 44.4 4e-24 85.0 30.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 AEO53668.1 - 4.8e-09 35.4 0.0 4.8e-09 35.4 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF4175 PF13779.1 AEO53668.1 - 0.75 7.4 25.7 1.1 6.8 17.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Trp_oprn_chp PF09534.5 AEO53668.1 - 1.2 8.6 0.0 1.2 8.6 0.0 2.9 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4407 PF14362.1 AEO53668.1 - 1.3 7.8 8.2 2.1 7.2 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GPCR_chapero_1 PF11904.3 AEO53668.1 - 1.5 7.8 8.8 2.4 7.2 6.1 1.2 1 0 0 1 1 1 0 GPCR-chaperone SprA-related PF12118.3 AEO53668.1 - 2.5 7.3 24.7 3.5 6.8 17.2 1.1 1 0 0 1 1 1 0 SprA-related family Suf PF05843.9 AEO53668.1 - 7.9 6.1 11.5 13 5.4 8.0 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) NnrS PF05940.7 AEO53669.1 - 0.046 12.6 0.0 0.051 12.4 0.0 1.0 1 0 0 1 1 1 0 NnrS protein Glyco_hydro_26 PF02156.10 AEO53670.1 - 1.5e-92 310.4 3.1 2.1e-92 309.9 2.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 NTPase_I-T PF01931.13 AEO53671.1 - 0.023 14.4 0.0 0.037 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF84 CorA PF01544.13 AEO53672.1 - 2.8e-08 33.1 0.4 4.4e-08 32.5 0.3 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Ribosomal_L44 PF00935.14 AEO53673.1 - 4.9e-35 119.3 11.8 6.9e-35 118.8 8.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 Ribosomal_L33 PF00471.15 AEO53673.1 - 1.1 9.5 9.2 0.37 11.0 1.0 2.7 2 1 0 2 2 2 0 Ribosomal protein L33 GFO_IDH_MocA PF01408.17 AEO53677.1 - 2.6e-19 69.8 0.0 4.7e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 AEO53677.1 - 9.1e-08 31.8 0.0 2e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 AEO53677.1 - 0.00017 21.9 0.0 0.00034 20.9 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain AAA_33 PF13671.1 AEO53677.1 - 0.14 12.0 0.2 0.3 10.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain bZIP_1 PF00170.16 AEO53678.1 - 2.9e-05 23.9 6.1 4.7e-05 23.2 4.2 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 AEO53678.1 - 0.0073 16.1 6.5 0.016 15.0 4.5 1.5 1 0 0 1 1 1 1 Basic region leucine zipper DUF2397 PF09660.5 AEO53678.1 - 0.37 9.3 6.6 0.56 8.7 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) DUF349 PF03993.7 AEO53678.1 - 0.57 10.3 5.2 1.1 9.5 3.6 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) RRM_1 PF00076.17 AEO53679.1 - 1.1e-18 66.5 0.0 1.2e-10 40.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO53679.1 - 1.3e-18 66.7 0.0 1.3e-10 41.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO53679.1 - 3.3e-15 55.6 0.0 1.2e-07 31.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_23 PF13489.1 AEO53681.1 - 2.5e-24 85.8 0.0 4.4e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO53681.1 - 7.9e-09 36.0 0.0 9.8e-08 32.5 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO53681.1 - 9.8e-08 32.3 0.0 7.7e-07 29.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO53681.1 - 8.5e-07 28.6 0.0 1.3e-05 24.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO53681.1 - 2.7e-06 27.7 0.0 5.7e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO53681.1 - 0.0035 17.3 0.3 0.04 13.9 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 AEO53681.1 - 0.0038 17.2 0.0 0.0062 16.5 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.14 AEO53681.1 - 0.0056 16.2 0.0 0.2 11.1 0.0 2.2 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 AEO53681.1 - 0.0093 15.1 0.0 0.091 11.8 0.0 2.3 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 AEO53681.1 - 0.045 14.1 0.0 0.14 12.5 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 AEO53681.1 - 0.047 12.7 0.0 0.075 12.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 AEO53681.1 - 0.15 11.3 0.0 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain MFS_1 PF07690.11 AEO53682.1 - 4.4e-44 150.6 54.8 4.4e-44 150.6 38.0 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 AEO53682.1 - 1.7e-16 59.6 25.9 2.8e-16 58.8 17.9 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 AEO53682.1 - 3.4e-16 58.8 8.1 3.4e-16 58.8 5.6 3.1 2 1 1 3 3 3 2 Sugar (and other) transporter DUF3357 PF11837.3 AEO53682.1 - 4.2 7.2 6.3 12 5.8 0.4 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3357) HMG-CoA_red PF00368.13 AEO53683.1 - 1.6e-154 514.0 7.0 2e-154 513.7 4.9 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 AEO53683.1 - 1.2e-46 158.2 0.6 2e-46 157.4 0.4 1.4 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 AEO53683.1 - 5.1e-13 48.7 3.0 1.3e-12 47.4 2.1 1.7 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 AEO53683.1 - 4.3e-06 24.9 2.5 6.8e-06 24.3 1.7 1.2 1 0 0 1 1 1 1 Patched family Auts2 PF15336.1 AEO53683.1 - 0.32 11.0 5.2 0.054 13.5 0.4 2.0 2 0 0 2 2 2 0 Autism susceptibility gene 2 protein Isochorismatase PF00857.15 AEO53684.1 - 6.4e-27 94.5 0.0 1.5e-26 93.3 0.0 1.6 1 1 0 1 1 1 1 Isochorismatase family AA_permease_2 PF13520.1 AEO53685.1 - 2e-77 260.5 23.5 2.5e-77 260.2 16.3 1.1 1 0 0 1 1 1 1 Amino acid permease Aa_trans PF01490.13 AEO53685.1 - 0.0033 15.9 9.1 0.086 11.2 4.5 2.4 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein DUF2611 PF11022.3 AEO53685.1 - 0.27 11.3 4.3 6.3 6.9 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2611) Cupin_2 PF07883.6 AEO53686.1 - 8.8e-22 76.3 0.1 5.9e-10 38.4 0.0 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_1 PF00190.17 AEO53686.1 - 4.4e-21 74.8 0.0 2.3e-09 36.8 0.0 2.3 2 0 0 2 2 2 2 Cupin Cupin_3 PF05899.7 AEO53686.1 - 3.7e-05 23.0 0.1 0.18 11.1 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) MannoseP_isomer PF01050.13 AEO53686.1 - 0.00022 20.8 0.0 0.022 14.3 0.0 2.1 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase 3-HAO PF06052.7 AEO53686.1 - 0.0011 18.4 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase AraC_binding PF02311.14 AEO53686.1 - 0.15 11.7 0.0 0.5 10.0 0.0 1.8 2 0 0 2 2 2 0 AraC-like ligand binding domain GPI-anchored PF10342.4 AEO53687.1 - 1.1e-17 64.3 1.1 1.1e-17 64.3 0.8 1.6 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family RNA_pol_Rpc34 PF05158.7 AEO53688.1 - 3.7e-128 427.3 0.0 5.6e-128 426.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit RPA_C PF08784.6 AEO53688.1 - 0.00017 21.9 1.8 0.0073 16.7 0.0 3.3 2 1 0 2 2 2 1 Replication protein A C terminal DUF2005 PF09407.5 AEO53688.1 - 0.02 13.6 0.1 0.03 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2005) HTH_34 PF13601.1 AEO53688.1 - 0.024 14.6 0.0 0.073 13.1 0.0 1.7 1 0 0 1 1 1 0 Winged helix DNA-binding domain MarR PF01047.17 AEO53688.1 - 0.036 13.7 0.0 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 MarR family Rrf2 PF02082.15 AEO53688.1 - 0.049 13.7 0.0 6.7 6.9 0.0 2.5 2 0 0 2 2 2 0 Transcriptional regulator HTH_36 PF13730.1 AEO53688.1 - 0.056 13.5 0.0 0.18 11.9 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain B-block_TFIIIC PF04182.7 AEO53688.1 - 0.062 13.1 0.0 0.29 11.0 0.0 2.1 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC TrmB PF01978.14 AEO53688.1 - 0.12 12.0 0.2 9.6 5.9 0.1 2.8 2 1 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Pro_isomerase PF00160.16 AEO53689.1 - 3.1e-40 137.9 0.4 3.9e-40 137.6 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ENTH PF01417.15 AEO53690.1 - 2.4e-49 166.3 0.4 3.3e-49 165.8 0.2 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 AEO53690.1 - 0.0005 18.8 0.1 0.00069 18.4 0.1 1.2 1 0 0 1 1 1 1 ANTH domain GRP PF07172.6 AEO53690.1 - 0.026 15.0 15.7 0.059 13.8 10.9 1.5 1 0 0 1 1 1 0 Glycine rich protein family DUF3754 PF12576.3 AEO53691.1 - 0.045 13.3 0.1 0.075 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3754) MARVEL PF01284.18 AEO53691.1 - 0.4 10.4 8.8 0.64 9.8 6.1 1.2 1 0 0 1 1 1 0 Membrane-associating domain DUF4231 PF14015.1 AEO53691.1 - 4 7.4 6.3 2.1 8.3 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Fungal_trans_2 PF11951.3 AEO53692.1 - 5.3e-53 179.9 0.9 6.8e-53 179.6 0.6 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO53692.1 - 5.6e-08 32.5 5.5 1e-07 31.6 3.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hemerythrin PF01814.18 AEO53693.1 - 5.8e-10 39.4 0.1 7.7e-10 39.0 0.1 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain AAA_22 PF13401.1 AEO53694.1 - 4e-06 26.9 0.0 3.9e-05 23.8 0.0 2.3 1 1 1 2 2 2 1 AAA domain Acetyltransf_10 PF13673.1 AEO53694.1 - 8.7e-06 25.8 0.0 0.0001 22.4 0.0 2.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain NACHT PF05729.7 AEO53694.1 - 1.8e-05 24.4 0.0 4.2e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Acetyltransf_1 PF00583.19 AEO53694.1 - 2.1e-05 24.4 0.0 5.6e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family AAA_16 PF13191.1 AEO53694.1 - 0.00036 20.5 0.2 0.0036 17.2 0.1 2.6 1 1 0 1 1 1 1 AAA ATPase domain Acetyltransf_7 PF13508.1 AEO53694.1 - 0.0036 17.4 0.0 0.0089 16.1 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF2075 PF09848.4 AEO53694.1 - 0.0049 15.8 0.0 0.22 10.4 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 AEO53694.1 - 0.0055 16.9 0.0 0.017 15.2 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 AEO53694.1 - 0.044 12.6 0.0 0.088 11.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.1 AEO53694.1 - 0.091 12.6 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain SET PF00856.23 AEO53696.1 - 2.1e-14 54.1 0.0 1.4e-08 35.2 0.0 2.5 2 0 0 2 2 2 2 SET domain TPR_11 PF13414.1 AEO53696.1 - 4.5e-09 35.8 9.6 6e-06 25.8 0.2 3.3 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 AEO53696.1 - 1.2e-06 27.9 13.7 0.037 13.9 2.3 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 AEO53696.1 - 7.3e-06 25.8 4.4 0.0015 18.4 1.2 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 AEO53696.1 - 0.0034 16.9 10.2 0.26 10.9 1.2 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat SAF PF08666.7 AEO53696.1 - 0.011 16.1 0.1 17 5.8 0.0 3.3 3 0 0 3 3 3 0 SAF domain MFP2b PF12150.3 AEO53696.1 - 0.22 10.1 0.0 0.34 9.5 0.0 1.1 1 0 0 1 1 1 0 Cytosolic motility protein TPR_8 PF13181.1 AEO53696.1 - 3.1 7.8 6.4 54 3.9 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat SET PF00856.23 AEO53697.1 - 3.2e-12 47.0 0.1 4e-11 43.4 0.0 2.3 1 1 0 1 1 1 1 SET domain SAF PF08666.7 AEO53697.1 - 0.0073 16.6 0.1 1.5 9.2 0.0 2.4 2 0 0 2 2 2 2 SAF domain SUR7 PF06687.7 AEO53698.1 - 3.5e-09 36.5 0.0 4.8e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 SUR7/PalI family DUF106 PF01956.11 AEO53698.1 - 0.076 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Integral membrane protein DUF106 Vpu PF00558.14 AEO53698.1 - 0.23 11.0 1.8 0.4 10.2 0.2 2.0 2 0 0 2 2 2 0 Vpu protein Fig1 PF12351.3 AEO53698.1 - 0.53 10.1 8.4 0.94 9.3 5.8 1.5 1 1 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 Mito_fiss_reg PF05308.6 AEO53698.1 - 8 5.7 11.2 2.2 7.5 3.2 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator NAD_binding_4 PF07993.7 AEO53699.1 - 9.6e-68 227.7 0.0 1.3e-67 227.3 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 AEO53699.1 - 5.2e-54 183.2 0.0 1.2e-53 182.0 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme PP-binding PF00550.20 AEO53699.1 - 4.5e-12 46.0 0.0 8.6e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 AEO53699.1 - 6.7e-12 45.3 0.0 1.2e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.1 AEO53699.1 - 8e-08 33.1 0.0 7e-07 30.1 0.0 2.7 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 AEO53699.1 - 9.7e-08 31.0 0.0 3.3e-07 29.2 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 AEO53699.1 - 0.0016 18.3 0.2 0.0075 16.1 0.1 2.1 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 AEO53699.1 - 0.012 15.5 0.0 0.51 10.3 0.0 2.7 1 1 0 1 1 1 0 NADH(P)-binding RmlD_sub_bind PF04321.12 AEO53699.1 - 0.047 12.5 0.0 1.4 7.7 0.0 2.3 2 0 0 2 2 2 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 AEO53699.1 - 0.062 12.1 0.0 0.14 11.0 0.0 1.6 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Peptidase_S28 PF05577.7 AEO53700.1 - 5e-35 120.9 0.0 9.4e-34 116.7 0.0 2.1 1 1 0 1 1 1 1 Serine carboxypeptidase S28 DUF3632 PF12311.3 AEO53702.1 - 0.032 14.0 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3632) MFS_1 PF07690.11 AEO53703.1 - 8.4e-05 21.4 4.5 8.4e-05 21.4 3.1 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily Pkinase PF00069.20 AEO53704.1 - 1.9e-73 246.8 0.0 3.1e-73 246.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO53704.1 - 3.1e-37 128.0 0.0 6.6e-37 126.9 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO53704.1 - 0.00041 19.4 2.2 0.57 9.0 0.0 2.9 3 0 0 3 3 3 2 Kinase-like APH PF01636.18 AEO53704.1 - 0.0074 16.0 1.7 0.049 13.3 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family CDC45 PF02724.9 AEO53704.1 - 0.91 7.4 9.8 1.6 6.6 6.8 1.3 1 0 0 1 1 1 0 CDC45-like protein Bcl-2_BAD PF10514.4 AEO53704.1 - 5.9 6.8 15.4 2.9 7.8 0.3 2.9 2 1 1 3 3 3 0 Pro-apoptotic Bcl-2 protein, BAD 2OG-FeII_Oxy PF03171.15 AEO53706.1 - 0.011 16.0 0.0 2.6 8.4 0.0 2.3 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 AEO53706.1 - 0.018 15.5 0.1 0.046 14.2 0.0 1.7 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Amidohydro_3 PF07969.6 AEO53707.1 - 1.7e-51 175.7 15.5 2.1e-51 175.4 10.8 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 AEO53707.1 - 2.9e-08 33.3 0.0 1.5e-07 31.1 0.0 2.3 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.15 AEO53707.1 - 1.3e-05 25.0 0.7 0.014 15.1 0.0 2.7 3 0 0 3 3 3 2 Amidohydrolase family Beta-lactamase PF00144.19 AEO53708.1 - 7.6e-33 113.9 1.6 1.3e-32 113.1 1.1 1.3 1 1 0 1 1 1 1 Beta-lactamase Amidohydro_2 PF04909.9 AEO53709.1 - 4.2e-39 134.7 3.9 6.3e-39 134.1 2.2 1.7 2 1 0 2 2 2 1 Amidohydrolase TatD_DNase PF01026.16 AEO53709.1 - 0.021 14.0 0.0 0.066 12.4 0.0 1.8 2 0 0 2 2 2 0 TatD related DNase p450 PF00067.17 AEO53710.1 - 1.1e-48 166.0 0.0 1.8e-48 165.2 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Aldedh PF00171.17 AEO53711.1 - 7.1e-143 476.2 0.0 9.4e-143 475.8 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ribonuc_L-PSP PF01042.16 AEO53712.1 - 8e-19 67.5 0.0 1.1e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP Mago-bind PF09282.5 AEO53712.1 - 0.13 11.8 0.4 0.45 10.1 0.1 2.0 2 0 0 2 2 2 0 Mago binding AA_permease PF00324.16 AEO53713.1 - 1.9e-120 402.4 43.3 2.3e-120 402.1 30.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AEO53713.1 - 6.7e-29 100.6 48.8 8.7e-29 100.3 33.8 1.0 1 0 0 1 1 1 1 Amino acid permease Ldh_1_N PF00056.18 AEO53714.1 - 6.6e-43 145.9 0.5 1.1e-42 145.2 0.3 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 AEO53714.1 - 4.9e-29 101.2 0.0 8.7e-29 100.4 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Shikimate_DH PF01488.15 AEO53714.1 - 1.4e-05 25.1 0.3 7.2e-05 22.9 0.1 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Glyco_hydro_4 PF02056.11 AEO53714.1 - 2.6e-05 23.6 0.7 0.09 12.0 0.0 3.1 2 1 1 3 3 3 2 Family 4 glycosyl hydrolase DAO PF01266.19 AEO53714.1 - 6.2e-05 22.0 0.7 0.00011 21.2 0.5 1.6 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 AEO53714.1 - 0.0046 17.1 0.4 0.01 16.0 0.3 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 AEO53714.1 - 0.0069 15.7 1.3 0.04 13.2 0.9 2.1 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_2 PF07992.9 AEO53714.1 - 0.0093 15.8 0.0 0.017 15.0 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AEO53714.1 - 0.013 15.5 2.1 0.076 13.0 0.5 2.3 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 AEO53714.1 - 0.014 15.3 1.1 0.045 13.7 0.6 2.1 1 1 1 2 2 2 0 TrkA-N domain OTCace PF00185.19 AEO53714.1 - 0.021 14.6 0.1 0.12 12.2 0.0 2.0 2 0 0 2 2 2 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Thi4 PF01946.12 AEO53714.1 - 0.022 13.8 0.3 0.053 12.6 0.2 1.6 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.13 AEO53714.1 - 0.027 14.1 0.7 0.069 12.8 0.1 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain OCD_Mu_crystall PF02423.10 AEO53714.1 - 0.03 13.0 0.8 0.053 12.2 0.6 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family ApbA PF02558.11 AEO53714.1 - 0.045 13.1 0.5 0.096 12.1 0.4 1.7 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.22 AEO53714.1 - 0.082 13.3 0.1 0.2 12.0 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AEO53714.1 - 0.11 12.5 0.1 0.33 11.0 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Saccharop_dh PF03435.13 AEO53714.1 - 0.14 11.0 0.6 0.24 10.3 0.4 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase ThiF PF00899.16 AEO53714.1 - 0.16 11.8 1.2 0.34 10.7 0.7 1.6 1 1 0 1 1 1 0 ThiF family Methyltransf_26 PF13659.1 AEO53714.1 - 1.6 8.8 6.7 9.1 6.3 4.6 2.2 1 1 0 1 1 1 0 Methyltransferase domain Amidoligase_2 PF12224.3 AEO53715.1 - 9.8e-14 51.5 0.0 2e-13 50.5 0.0 1.4 1 1 0 1 1 1 1 Putative amidoligase enzyme Peptidase_A4 PF01828.12 AEO53716.1 - 3e-65 219.1 3.2 3.7e-65 218.8 2.2 1.1 1 0 0 1 1 1 1 Peptidase A4 family DUF824 PF05688.6 AEO53716.1 - 0.0014 18.1 0.1 0.0085 15.7 0.0 2.2 2 0 0 2 2 2 1 Salmonella repeat of unknown function (DUF824) DUF1212 PF06738.7 AEO53717.1 - 6.4e-56 188.8 1.2 6.6e-53 179.0 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 AEO53717.1 - 4.8e-21 75.0 26.9 4.4e-12 46.0 0.5 3.2 3 0 0 3 3 3 3 Protein of unknown function (DUF3815) KAR9 PF08580.5 AEO53717.1 - 5.3 5.1 8.6 9.9 4.2 6.0 1.3 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Hist_deacetyl PF00850.14 AEO53718.1 - 1.3e-77 261.2 0.2 3.8e-77 259.6 0.0 1.8 2 0 0 2 2 2 1 Histone deacetylase domain JAB PF01398.16 AEO53719.1 - 1.7e-35 121.2 0.1 3.7e-35 120.1 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 AEO53719.1 - 1.3e-26 92.8 0.9 2.6e-26 91.9 0.6 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 AEO53719.1 - 4.7e-09 35.7 0.0 8.9e-09 34.8 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Chordopox_A13L PF05961.6 AEO53719.1 - 0.033 14.1 0.2 0.72 9.8 0.1 2.3 2 0 0 2 2 2 0 Chordopoxvirus A13L protein DUF605 PF04652.11 AEO53722.1 - 6.5e-79 266.0 14.9 7.2e-79 265.9 10.3 1.0 1 0 0 1 1 1 1 Vta1 like Thioredoxin PF00085.15 AEO53723.1 - 3.5e-32 110.1 0.1 8.8e-25 86.3 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.1 AEO53723.1 - 9.1e-10 38.6 0.0 4.2e-09 36.4 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_2 PF13098.1 AEO53723.1 - 3.1e-08 33.8 1.8 9.7e-06 25.7 1.2 3.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 AEO53723.1 - 4e-06 26.8 0.4 0.0055 16.7 0.0 4.4 3 2 1 4 4 4 1 Thioredoxin-like Thioredoxin_7 PF13899.1 AEO53723.1 - 0.0086 16.0 0.0 0.024 14.6 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like FAIM1 PF06905.8 AEO53723.1 - 0.07 12.2 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Fas apoptotic inhibitory molecule (FAIM1) TraF PF13728.1 AEO53723.1 - 0.11 12.0 0.0 0.11 12.0 0.0 3.8 4 1 0 4 4 4 0 F plasmid transfer operon protein Thioredoxin_3 PF13192.1 AEO53723.1 - 0.12 12.2 0.2 2.2 8.1 0.0 2.8 3 0 0 3 3 3 0 Thioredoxin domain HyaE PF07449.6 AEO53723.1 - 0.13 12.1 0.0 2.1 8.2 0.0 2.8 2 1 0 2 2 2 0 Hydrogenase-1 expression protein HyaE DUF2360 PF10152.4 AEO53723.1 - 2.4 8.4 12.7 2.9 8.1 0.4 2.3 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) RNase_PH PF01138.16 AEO53724.1 - 4.2e-37 127.3 0.0 7.6e-37 126.5 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 DUF1180 PF06679.7 AEO53725.1 - 0.18 11.7 1.2 0.3 10.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF3786 PF12654.2 AEO53726.1 - 0.011 15.0 0.3 0.014 14.6 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3786) PALP PF00291.20 AEO53728.1 - 9.1e-54 182.7 6.8 3.5e-53 180.8 4.7 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Cons_hypoth698 PF03601.9 AEO53728.1 - 0.082 11.5 0.3 0.15 10.6 0.2 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 698 MFS_1 PF07690.11 AEO53729.1 - 7.2e-44 149.9 26.9 7.2e-44 149.9 18.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO53729.1 - 2.4e-10 39.5 8.0 2.4e-10 39.5 5.6 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.8 AEO53729.1 - 0.0012 17.0 6.0 0.0012 17.0 4.2 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector MFS_2 PF13347.1 AEO53729.1 - 0.0025 16.3 1.1 0.0025 16.3 0.8 3.4 3 1 1 4 4 4 1 MFS/sugar transport protein UCR_Fe-S_N PF10399.4 AEO53729.1 - 0.015 14.4 1.3 0.015 14.4 0.9 2.9 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal DUF3353 PF11833.3 AEO53729.1 - 1.5 8.2 9.8 2.5 7.5 4.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3353) Sugar_tr PF00083.19 AEO53730.1 - 2.8e-97 326.1 19.8 3.1e-97 325.9 13.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO53730.1 - 5.1e-26 91.2 28.5 2.2e-17 62.8 7.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_2_C PF02836.12 AEO53731.1 - 2.2e-105 351.8 0.0 3e-105 351.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.12 AEO53731.1 - 2.4e-53 180.9 0.0 7.3e-53 179.3 0.0 1.8 2 0 0 2 2 2 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.13 AEO53731.1 - 2.7e-51 173.4 0.3 5.2e-51 172.5 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 AEO53731.1 - 1e-15 58.1 0.2 2.3e-15 57.0 0.2 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_42 PF02449.10 AEO53731.1 - 0.0092 15.1 0.3 0.016 14.3 0.2 1.3 1 0 0 1 1 1 1 Beta-galactosidase Sugar_tr PF00083.19 AEO53732.1 - 2e-95 320.0 19.6 2.3e-95 319.8 13.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO53732.1 - 4.4e-34 117.7 37.8 1.1e-30 106.5 14.2 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 AEO53732.1 - 3.1e-05 22.3 4.6 0.0014 16.9 0.3 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Ni_hydr_CYTB PF01292.15 AEO53732.1 - 0.22 10.9 3.7 4.1 6.7 0.2 2.5 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 WD40 PF00400.27 AEO53733.1 - 9.2e-86 278.9 22.4 5.9e-15 54.5 0.4 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat eIF2A PF08662.6 AEO53733.1 - 5.2e-07 29.5 0.2 0.00051 19.8 0.0 3.2 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 AEO53733.1 - 1.9e-05 23.0 0.7 0.4 8.7 0.0 4.0 3 1 0 3 3 3 3 Nucleoporin Nup120/160 IKI3 PF04762.7 AEO53733.1 - 0.034 11.9 0.6 3.4 5.3 0.0 2.2 2 0 0 2 2 2 0 IKI3 family FAD_binding_9 PF08021.6 AEO53733.1 - 0.059 13.3 0.0 1.2 9.1 0.0 2.6 2 1 0 2 2 2 0 Siderophore-interacting FAD-binding domain NLE PF08154.7 AEO53733.1 - 0.087 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 NLE (NUC135) domain Glyco_transf_20 PF00982.16 AEO53735.1 - 2.8e-164 547.0 0.1 3.9e-164 546.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 AEO53735.1 - 1.7e-44 151.5 0.0 2.5e-44 150.9 0.0 1.2 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_transf_5 PF08323.6 AEO53735.1 - 0.011 15.2 0.5 0.02 14.3 0.3 1.3 1 0 0 1 1 1 0 Starch synthase catalytic domain Hydrolase_3 PF08282.7 AEO53735.1 - 0.26 10.8 0.0 4.6 6.7 0.0 2.4 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Aminotran_4 PF01063.14 AEO53736.1 - 1.5e-23 83.5 0.0 2e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV MutS_V PF00488.16 AEO53737.1 - 3.1e-69 232.9 0.0 4.7e-69 232.3 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 AEO53737.1 - 2.4e-28 99.3 0.6 6.7e-28 97.8 0.4 1.8 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.12 AEO53737.1 - 0.033 14.2 0.2 1 9.4 0.1 2.6 1 1 0 1 1 1 0 MutS domain II DUF221 PF02714.10 AEO53738.1 - 1.4e-95 319.9 17.9 2e-95 319.3 12.4 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 AEO53738.1 - 2.7e-42 144.0 1.5 2.7e-42 144.0 1.0 2.7 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 AEO53738.1 - 2e-18 66.6 0.2 3.7e-18 65.8 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_6 PF14259.1 AEO53738.1 - 0.14 12.1 0.1 18 5.4 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Dynamin_N PF00350.18 AEO53739.1 - 2.4e-29 102.3 0.0 4.9e-29 101.3 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 AEO53739.1 - 9e-10 37.8 0.0 2.5e-09 36.3 0.0 1.7 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 AEO53739.1 - 4.8e-05 23.2 0.0 0.00016 21.6 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 AEO53739.1 - 0.0038 17.7 0.0 0.0092 16.4 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein ABC_tran PF00005.22 AEO53739.1 - 0.0052 17.0 0.0 0.02 15.1 0.0 2.0 1 0 0 1 1 1 1 ABC transporter Phe_tRNA-synt_N PF02912.13 AEO53739.1 - 0.011 15.4 0.3 0.03 14.0 0.0 1.9 2 0 0 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain GED PF02212.13 AEO53739.1 - 0.13 12.1 1.7 0.28 11.1 0.4 2.1 2 0 0 2 2 2 0 Dynamin GTPase effector domain DUF605 PF04652.11 AEO53739.1 - 7.5 5.8 29.6 12 5.1 20.5 1.3 1 0 0 1 1 1 0 Vta1 like MFS_1 PF07690.11 AEO53741.1 - 4.4e-33 114.4 29.3 6.4e-33 113.9 20.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Cytochrom_B_N_2 PF13631.1 AEO53743.1 - 1.7e-06 27.9 0.1 1.9e-06 27.7 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.12 AEO53743.1 - 0.095 12.9 2.8 0.72 10.1 0.3 2.1 2 0 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD Oxidored_q1 PF00361.15 AEO53744.1 - 3.2e-20 72.5 5.0 3.2e-20 72.5 3.5 3.4 3 1 1 4 4 4 1 NADH-Ubiquinone/plastoquinone (complex I), various chains NADH5_C PF06455.6 AEO53744.1 - 2.6e-11 43.2 12.0 4e-08 32.8 6.2 2.8 2 1 0 2 2 2 2 NADH dehydrogenase subunit 5 C-terminus Oxidored_q1_C PF01010.14 AEO53744.1 - 0.1 12.0 11.6 0.0087 15.5 4.2 2.1 2 1 0 2 2 2 0 NADH-Ubiquinone oxidoreductase (complex I) subunit C-terminus Oxidored_q3 PF00499.15 AEO53745.1 - 7e-24 84.2 21.4 1e-23 83.7 14.8 1.3 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF4419 PF14388.1 AEO53746.1 - 3.3e-74 249.7 0.0 3.9e-74 249.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) FMO-like PF00743.14 AEO53749.1 - 4.1e-17 61.5 0.0 7.7e-17 60.6 0.0 1.4 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 AEO53749.1 - 3.7e-15 56.5 0.0 6.1e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AEO53749.1 - 4.6e-10 39.3 0.0 3.6e-09 36.5 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 AEO53749.1 - 8.7e-10 38.8 0.0 1.2e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 AEO53749.1 - 1e-09 38.3 0.1 9.6e-09 35.2 0.0 2.6 2 1 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 AEO53749.1 - 1.7e-06 27.2 0.2 9.9e-06 24.6 0.0 2.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 AEO53749.1 - 0.00027 19.9 0.0 0.0035 16.2 0.0 2.4 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 AEO53749.1 - 0.0027 18.0 0.0 4.6 7.7 0.1 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 AEO53749.1 - 0.011 14.2 0.0 0.016 13.6 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.7 AEO53749.1 - 0.012 14.5 0.0 0.024 13.5 0.0 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 AEO53749.1 - 0.016 14.3 0.1 0.026 13.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 AEO53749.1 - 0.023 13.7 0.0 0.043 12.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.9 AEO53749.1 - 0.087 11.4 0.0 0.16 10.5 0.0 1.4 1 0 0 1 1 1 0 Tryptophan halogenase 7tm_2 PF00002.19 AEO53750.1 - 3.7e-12 45.8 6.8 7.1e-12 44.9 4.7 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Git3 PF11710.3 AEO53750.1 - 1.2e-07 31.5 10.3 2.1e-07 30.7 7.2 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Dicty_CAR PF05462.6 AEO53750.1 - 6.2e-05 22.0 11.9 0.00014 20.8 8.3 1.5 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor DUF2905 PF11146.3 AEO53750.1 - 0.057 13.3 0.7 0.057 13.3 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2905) P12 PF12669.2 AEO53750.1 - 2 8.6 11.1 5.8 7.1 6.4 2.4 2 0 0 2 2 2 0 Virus attachment protein p12 family Methyltransf_16 PF10294.4 AEO53751.1 - 2.6e-15 56.3 0.0 4.1e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 AEO53751.1 - 1.6e-09 38.3 0.0 4.3e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO53751.1 - 0.00019 21.8 0.0 0.00057 20.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 AEO53751.1 - 0.00036 19.9 0.1 0.002 17.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 AEO53751.1 - 0.00063 19.7 1.5 0.0015 18.5 1.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO53751.1 - 0.0014 18.3 0.0 0.0024 17.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO53751.1 - 0.0017 18.8 0.0 0.004 17.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO53751.1 - 0.0043 16.6 0.0 0.0065 16.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Erv26 PF04148.8 AEO53753.1 - 1.1e-58 198.1 0.0 1.2e-58 197.9 0.0 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 DUF3377 PF11857.3 AEO53753.1 - 0.06 12.9 0.0 0.06 12.9 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) WBS_methylT PF12589.3 AEO53754.1 - 4.1e-18 65.6 7.0 7.5e-18 64.8 4.9 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 AEO53754.1 - 2.2e-10 40.8 0.0 4.4e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO53754.1 - 3.4e-06 27.3 0.0 9.9e-06 25.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO53754.1 - 4.8e-06 26.2 0.0 7.6e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO53754.1 - 3.7e-05 23.4 0.0 5.5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO53754.1 - 4.9e-05 23.7 0.0 0.00015 22.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 AEO53754.1 - 8.6e-05 22.1 0.0 0.00014 21.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 AEO53754.1 - 0.00011 22.7 0.0 0.00035 21.1 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain CMAS PF02353.15 AEO53754.1 - 0.00041 19.5 0.0 0.0035 16.4 0.0 2.0 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 AEO53754.1 - 0.00066 19.6 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AEO53754.1 - 0.0044 16.1 0.0 0.01 14.9 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Iso_dh PF00180.15 AEO53755.1 - 8e-81 271.6 0.0 9.4e-81 271.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Alpha-amylase PF00128.19 AEO53757.1 - 0.00066 19.1 0.0 0.0013 18.2 0.0 1.5 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Pkinase PF00069.20 AEO53758.1 - 7e-71 238.4 0.0 1e-70 237.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO53758.1 - 2.3e-50 171.1 0.0 3.9e-50 170.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO53758.1 - 0.00034 19.6 0.0 0.0019 17.2 0.0 1.9 2 0 0 2 2 2 1 Kinase-like PAT1 PF09770.4 AEO53758.1 - 9.5 4.3 39.5 0.033 12.4 18.8 2.0 1 1 1 2 2 2 0 Topoisomerase II-associated protein PAT1 Thioredoxin_7 PF13899.1 AEO53759.1 - 1.3e-13 50.8 0.0 2.7e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.15 AEO53759.1 - 1e-09 38.2 0.0 2e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 AEO53759.1 - 7.8e-09 34.9 0.7 1.8e-08 33.7 0.5 1.7 1 0 0 1 1 1 1 UBA-like domain Thioredox_DsbH PF03190.10 AEO53759.1 - 0.0041 16.8 0.0 0.0071 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_2 PF13098.1 AEO53759.1 - 0.071 13.3 0.1 0.2 11.8 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin-like domain Ecm29 PF13001.2 AEO53760.1 - 1.5e-16 60.0 0.0 1.9e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome stabiliser Sec7_N PF12783.2 AEO53760.1 - 0.15 11.4 0.0 0.19 11.1 0.0 1.1 1 0 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Ecm29 PF13001.2 AEO53761.1 - 2.2e-73 247.4 0.0 7e-73 245.8 0.0 1.9 2 0 0 2 2 2 1 Proteasome stabiliser HEAT PF02985.17 AEO53761.1 - 0.00028 20.7 6.8 0.51 10.5 0.0 7.3 7 0 0 7 7 7 1 HEAT repeat RRM_1 PF00076.17 AEO53762.1 - 3.9e-45 151.3 0.0 1.4e-16 59.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO53762.1 - 5.3e-25 87.1 0.0 5.7e-10 39.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO53762.1 - 6.6e-23 80.3 0.0 1.2e-08 34.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 AEO53762.1 - 6.3e-07 29.2 0.0 0.00014 21.6 0.0 2.8 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.1 AEO53762.1 - 9e-05 22.1 0.1 0.0032 17.2 0.0 2.8 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif TFIIA PF03153.8 AEO53765.1 - 0.0076 16.1 26.0 0.01 15.7 18.0 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Gcd10p PF04189.8 AEO53765.1 - 0.19 10.8 8.7 0.26 10.3 6.1 1.2 1 0 0 1 1 1 0 Gcd10p family Zip PF02535.17 AEO53765.1 - 0.91 8.4 7.0 0.084 11.8 1.9 1.5 2 0 0 2 2 2 0 ZIP Zinc transporter Med15 PF09606.5 AEO53765.1 - 1.4 7.0 37.2 1.8 6.6 25.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RR_TM4-6 PF06459.7 AEO53765.1 - 1.4 8.7 11.3 2.4 7.9 7.8 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 IncA PF04156.9 AEO53765.1 - 4.4 6.8 15.8 7.5 6.0 11.0 1.4 1 0 0 1 1 1 0 IncA protein AAA_23 PF13476.1 AEO53765.1 - 5.3 7.3 9.6 8.5 6.6 6.6 1.3 1 0 0 1 1 1 0 AAA domain Macoilin PF09726.4 AEO53765.1 - 6.2 4.9 14.9 7.8 4.6 10.3 1.1 1 0 0 1 1 1 0 Transmembrane protein Paramyxo_ncap PF00973.14 AEO53765.1 - 6.9 5.2 11.3 9.2 4.8 7.8 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF3513 PF12026.3 AEO53765.1 - 7.7 5.9 18.0 13 5.2 12.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) AA_permease_2 PF13520.1 AEO53766.1 - 1.9e-47 161.8 38.2 2.2e-47 161.5 26.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 AEO53766.1 - 8.3e-16 57.3 35.1 1.3e-15 56.7 24.3 1.3 1 0 0 1 1 1 1 Amino acid permease HipA_C PF07804.7 AEO53767.1 - 0.028 14.5 0.0 0.073 13.1 0.0 1.7 1 0 0 1 1 1 0 HipA-like C-terminal domain Cellulase PF00150.13 AEO53769.1 - 3.1e-53 180.7 4.1 4.2e-53 180.3 2.9 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 AEO53769.1 - 5.1e-13 48.4 12.6 5.1e-13 48.4 8.8 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain Vps39_2 PF10367.4 AEO53772.1 - 0.12 12.5 0.1 2.5 8.2 0.0 2.9 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 2 PAT1 PF09770.4 AEO53774.1 - 0.41 8.8 7.4 0.49 8.5 5.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Glycolytic PF00274.14 AEO53775.1 - 0.025 12.9 0.0 0.026 12.9 0.0 1.0 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-I DUF4360 PF14273.1 AEO53777.1 - 3.3e-13 49.7 3.0 1.5e-11 44.3 2.1 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4360) Sipho_tail PF05709.6 AEO53777.1 - 0.035 13.2 0.3 0.045 12.8 0.2 1.2 1 0 0 1 1 1 0 Phage tail protein MFS_1 PF07690.11 AEO53778.1 - 4.9e-36 124.1 29.5 4.9e-36 124.1 20.5 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO53778.1 - 5.2e-07 28.6 9.9 5.2e-07 28.6 6.9 2.6 2 2 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 AEO53778.1 - 0.00011 20.5 2.7 0.00016 20.0 1.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) SUZ-C PF12901.2 AEO53780.1 - 0.0096 15.5 2.6 0.024 14.2 1.8 1.7 1 0 0 1 1 1 1 SUZ-C motif DUF3237 PF11578.3 AEO53781.1 - 2.4e-37 127.5 0.0 3.4e-37 127.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) zf-BED PF02892.10 AEO53781.1 - 1.6e-07 30.9 2.8 0.0062 16.2 0.1 2.3 2 0 0 2 2 2 2 BED zinc finger Herpes_capsid PF06112.6 AEO53781.1 - 0.0032 17.4 0.3 0.016 15.2 0.1 2.1 2 0 0 2 2 2 1 Gammaherpesvirus capsid protein zf-C2H2_2 PF12756.2 AEO53781.1 - 0.23 11.5 5.2 6.5 6.9 0.5 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) PAT1 PF09770.4 AEO53781.1 - 4.4 5.4 7.2 5.6 5.0 5.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HLH PF00010.21 AEO53782.1 - 2.1e-07 30.5 0.0 4e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CENP-F_leu_zip PF10473.4 AEO53783.1 - 0.017 14.9 2.2 0.03 14.1 1.0 1.8 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MerR_2 PF13591.1 AEO53783.1 - 0.058 12.9 2.0 0.092 12.3 0.8 1.8 2 0 0 2 2 2 0 MerR HTH family regulatory protein DivIC PF04977.10 AEO53783.1 - 0.31 10.5 6.2 0.65 9.5 4.3 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF2802 PF10975.3 AEO53783.1 - 0.67 9.7 3.9 0.83 9.4 1.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) SlyX PF04102.7 AEO53783.1 - 1.6 9.1 5.4 14 6.1 3.6 2.2 2 0 0 2 2 2 0 SlyX PBP1_TM PF14812.1 AEO53785.1 - 4.1 7.7 7.3 1.9 8.8 2.3 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NAD_binding_10 PF13460.1 AEO53786.1 - 5.5e-06 26.5 0.0 7.2e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding DapB_N PF01113.15 AEO53786.1 - 7.7e-06 25.8 0.0 1.7e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.16 AEO53786.1 - 0.0029 17.0 0.0 0.0083 15.5 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 AEO53786.1 - 0.0061 16.4 0.4 0.048 13.5 0.0 2.3 2 1 1 3 3 3 1 short chain dehydrogenase NmrA PF05368.8 AEO53786.1 - 0.01 15.0 0.1 0.069 12.3 0.0 2.0 2 0 0 2 2 2 0 NmrA-like family Polysacc_synt_2 PF02719.10 AEO53786.1 - 0.028 13.3 0.0 0.041 12.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 AEO53786.1 - 0.031 13.1 0.0 0.073 11.9 0.0 1.6 1 0 0 1 1 1 0 Male sterility protein Semialdhyde_dh PF01118.19 AEO53786.1 - 0.046 14.0 0.0 0.078 13.2 0.0 1.6 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 AEO53786.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain 3Beta_HSD PF01073.14 AEO53786.1 - 0.12 10.9 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Bd3614-deam PF14439.1 AEO53787.1 - 0.38 10.6 4.8 0.84 9.4 3.3 1.6 1 0 0 1 1 1 0 Bd3614-like deaminase RNase_H PF00075.19 AEO53788.1 - 2.6e-13 50.4 0.0 3.7e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 AEO53788.1 - 6.2e-05 22.7 0.0 0.1 12.3 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase-like DnaJ PF00226.26 AEO53789.1 - 5.7e-12 45.1 1.3 1.3e-11 44.0 0.5 1.8 1 1 0 1 1 1 1 DnaJ domain FKBP_N PF01346.13 AEO53789.1 - 0.61 10.1 5.2 2.4 8.1 0.9 2.3 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase CBM_X PF06204.6 AEO53790.1 - 0.073 12.5 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative carbohydrate binding domain GMC_oxred_N PF00732.14 AEO53791.1 - 4.6e-21 75.2 0.0 5.2e-21 75.0 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase Zn_clus PF00172.13 AEO53792.1 - 7.5e-07 28.9 7.1 7.5e-07 28.9 4.9 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 AEO53792.1 - 0.015 13.8 3.7 0.014 13.9 1.8 1.3 1 1 0 1 1 1 0 Fungal specific transcription factor domain DUF1510 PF07423.6 AEO53793.1 - 0.017 14.4 2.4 0.021 14.1 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) HnRNP_M PF11532.3 AEO53793.1 - 0.45 10.6 5.0 0.87 9.7 3.5 1.5 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein M Epiglycanin_C PF14654.1 AEO53794.1 - 0.0025 17.7 0.2 0.0037 17.2 0.1 1.2 1 0 0 1 1 1 1 Mucin, catalytic, TM and cytoplasmic tail region Herpes_gE PF02480.11 AEO53794.1 - 0.053 11.7 0.0 0.069 11.4 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E RCR PF12273.3 AEO53794.1 - 0.36 11.3 3.0 0.7 10.4 2.1 1.5 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Notch PF00066.12 AEO53794.1 - 0.37 11.0 0.1 0.37 11.0 0.1 2.2 3 0 0 3 3 3 0 LNR domain hDGE_amylase PF14701.1 AEO53795.1 - 6e-178 592.0 0.0 7.7e-178 591.7 0.0 1.1 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 AEO53795.1 - 6.3e-117 390.4 0.0 1.5e-116 389.1 0.0 1.6 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 AEO53795.1 - 5.8e-89 297.7 0.0 9.1e-89 297.0 0.0 1.3 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 AEO53795.1 - 8.6e-27 92.8 0.0 1.9e-26 91.7 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 AEO53795.1 - 0.00028 20.4 0.0 0.68 9.2 0.0 2.3 2 0 0 2 2 2 2 Alpha amylase, catalytic domain NAD_Gly3P_dh_N PF01210.18 AEO53796.1 - 1.8e-46 157.7 0.1 5e-46 156.3 0.0 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 AEO53796.1 - 3.4e-37 127.4 0.0 5e-37 126.8 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus DUF4591 PF15261.1 AEO53797.1 - 0.0093 16.2 0.2 0.039 14.2 0.1 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4591) Peptidase_C48 PF02902.14 AEO53798.1 - 6.8e-15 55.2 0.1 4e-07 29.8 0.0 2.6 2 1 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain SLX9 PF15341.1 AEO53799.1 - 9.7e-34 116.4 9.9 6.3e-33 113.7 6.9 2.1 1 1 0 1 1 1 1 Ribosome biogenesis protein SLX9 DUF932 PF06067.6 AEO53799.1 - 0.014 14.7 0.6 0.019 14.2 0.1 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF932) YPEB PF14620.1 AEO53799.1 - 0.024 13.6 0.4 0.03 13.3 0.3 1.2 1 0 0 1 1 1 0 YpeB sporulation DUF4570 PF15134.1 AEO53799.1 - 2.2 8.1 6.0 5.6 6.8 0.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4570) ThiF PF00899.16 AEO53800.1 - 4.8e-39 133.2 0.0 7.3e-39 132.7 0.0 1.3 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 AEO53800.1 - 1.2e-15 56.7 0.8 3.4e-14 52.2 0.4 2.3 2 0 0 2 2 2 1 MoeZ/MoeB domain Rhodanese PF00581.15 AEO53800.1 - 1.2e-12 48.1 0.0 2.5e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 AEO53800.1 - 8.6e-05 22.6 0.0 0.00029 20.9 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 AEO53800.1 - 0.13 12.5 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Radical_SAM PF04055.16 AEO53800.1 - 0.13 12.4 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Radical SAM superfamily Pam17 PF08566.5 AEO53801.1 - 3.9e-64 215.5 0.0 5.5e-64 215.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 DUF204 PF02659.10 AEO53801.1 - 0.044 13.9 0.7 0.088 12.9 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF Chromo PF00385.19 AEO53802.1 - 1.4e-08 34.2 3.8 3.1e-08 33.1 2.7 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DnaJ PF00226.26 AEO53803.1 - 1.1e-17 63.4 2.0 1.9e-17 62.7 1.4 1.4 1 0 0 1 1 1 1 DnaJ domain RhoGAP PF00620.22 AEO53803.1 - 0.02 14.4 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 RhoGAP domain DUF456 PF04306.8 AEO53803.1 - 0.038 14.0 0.4 0.051 13.6 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) DUF4175 PF13779.1 AEO53803.1 - 0.68 7.5 11.2 0.88 7.1 7.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SR-25 PF10500.4 AEO53803.1 - 0.8 9.1 16.3 2.2 7.6 7.1 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Proteasome PF00227.21 AEO53805.1 - 4.3e-45 153.3 0.0 1.2e-30 106.2 0.0 2.3 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 AEO53805.1 - 1.2e-11 43.6 0.9 1.6e-11 43.3 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DNA_pol_phi PF04931.8 AEO53806.1 - 1.7e-52 178.2 28.7 2.7e-36 124.7 16.6 3.0 2 1 0 2 2 2 2 DNA polymerase phi Caleosin PF05042.8 AEO53806.1 - 0.21 11.1 3.1 0.33 10.4 0.3 2.5 3 0 0 3 3 3 0 Caleosin related protein Rhodanese PF00581.15 AEO53808.1 - 1.9e-12 47.4 0.0 3.7e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain CwfJ_C_1 PF04677.10 AEO53809.1 - 9.3e-26 89.8 0.0 1.9e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 AEO53809.1 - 4.9e-23 81.4 0.1 1.1e-22 80.3 0.1 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 DNA_RNApol_7kD PF03604.8 AEO53810.1 - 1.9e-06 27.2 0.5 3.5e-06 26.3 0.1 1.6 2 0 0 2 2 2 1 DNA directed RNA polymerase, 7 kDa subunit Kelch_6 PF13964.1 AEO53810.1 - 0.041 14.0 0.0 0.081 13.1 0.0 1.4 1 0 0 1 1 1 0 Kelch motif CTD PF12815.2 AEO53810.1 - 0.065 13.6 1.3 0.084 13.2 0.9 1.2 1 0 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 DRIM PF07539.7 AEO53811.1 - 9.4e-43 145.0 0.0 4e-42 142.9 0.0 2.2 1 0 0 1 1 1 1 Down-regulated in metastasis HEAT PF02985.17 AEO53811.1 - 1.1e-06 28.1 2.1 0.85 9.8 0.0 8.6 10 0 0 10 10 10 1 HEAT repeat Vac14_Fab1_bd PF12755.2 AEO53811.1 - 0.015 15.6 0.1 4.9 7.6 0.0 3.7 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region zf-DNL PF05180.7 AEO53812.1 - 6.5e-29 99.4 0.2 1e-28 98.8 0.1 1.3 1 0 0 1 1 1 1 DNL zinc finger zf-CSL PF05207.8 AEO53812.1 - 0.094 12.2 0.2 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 CSL zinc finger Hamartin PF04388.7 AEO53812.1 - 0.1 11.2 5.7 0.12 10.9 3.9 1.1 1 0 0 1 1 1 0 Hamartin protein Folate_carrier PF01770.13 AEO53812.1 - 0.18 10.2 0.8 0.23 9.9 0.6 1.1 1 0 0 1 1 1 0 Reduced folate carrier DUF2360 PF10152.4 AEO53812.1 - 0.44 10.8 8.2 0.78 10.0 5.7 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) PAT1 PF09770.4 AEO53812.1 - 0.48 8.5 18.6 0.56 8.3 12.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hid1 PF12722.2 AEO53812.1 - 0.63 7.6 6.2 0.73 7.4 4.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RAB3GAP2_N PF14655.1 AEO53812.1 - 0.96 8.3 4.8 1.4 7.8 3.3 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus CDK5_activator PF03261.10 AEO53812.1 - 0.97 8.6 6.7 1.3 8.3 4.6 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein TFIIA PF03153.8 AEO53812.1 - 1.3 8.8 15.7 1.8 8.3 10.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.12 AEO53812.1 - 2.2 7.0 5.1 2.8 6.6 3.5 1.1 1 0 0 1 1 1 0 Presenilin APC_CDC26 PF10471.4 AEO53812.1 - 2.5 8.9 18.1 5.1 7.9 12.6 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 PIH1 PF08190.7 AEO53812.1 - 3.1 7.1 11.6 4 6.7 8.1 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Pex16 PF08610.5 AEO53812.1 - 4.5 6.1 9.1 6.2 5.7 6.3 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) vMSA PF00695.14 AEO53812.1 - 4.7 6.3 8.6 6.5 5.8 5.9 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus DUF4557 PF15101.1 AEO53812.1 - 6.2 6.6 10.9 8.6 6.1 7.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Retinal PF15449.1 AEO53812.1 - 7.3 4.1 21.2 10 3.6 14.7 1.1 1 0 0 1 1 1 0 Retinal protein PHD_3 PF13922.1 AEO53812.1 - 7.8 6.8 10.3 19 5.5 7.2 1.7 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx Cullin PF00888.17 AEO53813.1 - 4e-125 418.6 0.3 5.7e-125 418.1 0.2 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 AEO53813.1 - 2.4e-27 94.5 1.5 4.8e-27 93.5 0.5 2.0 2 0 0 2 2 2 1 Cullin protein neddylation domain HTH_15 PF12324.3 AEO53813.1 - 0.081 12.5 0.0 6.3 6.5 0.0 3.0 2 0 0 2 2 2 0 Helix-turn-helix domain of alkylmercury lyase DUF1640 PF07798.6 AEO53816.1 - 2.8e-66 222.9 7.6 3.3e-66 222.6 5.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Syntaxin PF00804.20 AEO53816.1 - 0.09 12.9 10.4 0.13 12.4 5.1 2.3 1 1 1 2 2 2 0 Syntaxin WTX PF09422.5 AEO53816.1 - 0.1 11.5 2.8 0.12 11.2 2.0 1.1 1 0 0 1 1 1 0 WTX protein CLAMP PF14769.1 AEO53816.1 - 0.11 12.7 0.1 0.21 11.7 0.1 1.5 1 0 0 1 1 1 0 Flagellar C1a complex subunit C1a-32 Nol1_Nop2_Fmu PF01189.12 AEO53817.1 - 5.9e-101 337.5 0.0 9.2e-101 336.9 0.0 1.3 1 0 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 AEO53817.1 - 0.01 15.8 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Clathrin PF00637.15 AEO53818.1 - 5.4e-205 671.2 34.6 3.4e-34 117.4 0.9 7.7 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 AEO53818.1 - 2.3e-34 117.0 0.9 1.1e-33 114.9 0.6 2.3 1 0 0 1 1 1 1 Clathrin-H-link Clathrin_propel PF01394.15 AEO53818.1 - 1.1e-30 103.7 0.2 1.7e-05 24.7 0.0 7.6 7 0 0 7 7 7 7 Clathrin propeller repeat TPR_12 PF13424.1 AEO53818.1 - 2.7e-05 24.0 3.0 1 9.3 0.0 6.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 AEO53818.1 - 4.5e-05 22.9 9.1 4.8 7.2 0.0 8.1 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_14 PF13428.1 AEO53818.1 - 0.0033 17.9 20.0 11 6.9 0.1 9.7 10 0 0 10 10 10 1 Tetratricopeptide repeat Ank_3 PF13606.1 AEO53818.1 - 0.092 13.0 0.0 1.4 9.3 0.0 3.1 2 0 0 2 2 2 0 Ankyrin repeat TPR_1 PF00515.23 AEO53818.1 - 0.2 11.3 7.8 9.7 5.9 0.0 6.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Clathrin-link PF09268.5 AEO53818.1 - 2.8 7.0 9.7 3 6.9 0.2 3.0 3 0 0 3 3 3 0 Clathrin, heavy-chain linker TPR_2 PF07719.12 AEO53818.1 - 6.6 6.9 17.3 13 6.0 0.0 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat Hepar_II_III PF07940.8 AEO53820.1 - 0.017 14.9 0.5 0.021 14.6 0.3 1.3 1 1 0 1 1 1 0 Heparinase II/III-like protein ATP-synt_ab PF00006.20 AEO53823.1 - 2.9e-69 232.8 0.0 4.6e-69 232.2 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 AEO53823.1 - 2.4e-27 95.6 1.8 3.5e-27 95.1 0.5 1.9 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 AEO53823.1 - 1.3e-15 57.3 2.6 3.5e-15 55.9 1.8 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 AEO53823.1 - 0.005 16.7 0.7 0.012 15.4 0.5 1.7 1 0 0 1 1 1 1 HAS barrel domain Arch_ATPase PF01637.13 AEO53823.1 - 0.015 15.0 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase Carb_kinase PF01256.12 AEO53824.1 - 1.2e-53 181.8 0.2 4.4e-53 180.0 0.1 1.9 1 1 0 1 1 1 1 Carbohydrate kinase PfkB PF00294.19 AEO53824.1 - 0.0059 15.7 0.0 0.02 14.0 0.0 1.7 2 0 0 2 2 2 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 AEO53824.1 - 0.012 14.7 0.0 0.034 13.3 0.0 1.7 1 1 0 1 1 1 0 Phosphomethylpyrimidine kinase Chorion_2 PF03964.10 AEO53824.1 - 4 8.0 9.3 2.3 8.7 0.9 2.6 3 0 0 3 3 3 0 Chorion family 2 Ribosomal_L5_C PF00673.16 AEO53827.1 - 1.5e-22 79.1 0.0 2.1e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 AEO53827.1 - 2e-21 75.5 0.1 5.6e-21 74.0 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 LSM PF01423.17 AEO53828.1 - 7.7e-18 63.8 0.0 1.1e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain MPC PF03650.8 AEO53829.1 - 3e-34 117.5 0.0 3.5e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) MtN3_slv PF03083.11 AEO53829.1 - 0.034 14.0 0.2 0.045 13.6 0.2 1.3 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange CPSase_L_D2 PF02786.12 AEO53830.1 - 1.2e-79 266.5 0.3 2.3e-79 265.5 0.2 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 AEO53830.1 - 4.7e-68 228.4 0.0 8.5e-68 227.6 0.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_C PF02785.14 AEO53830.1 - 1.7e-31 108.3 0.0 4.3e-31 107.0 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 AEO53830.1 - 1.2e-28 99.4 0.0 2.5e-28 98.3 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain HMGL-like PF00682.14 AEO53830.1 - 7.5e-25 87.9 0.0 1.3e-24 87.2 0.0 1.4 1 0 0 1 1 1 1 HMGL-like ATP-grasp_4 PF13535.1 AEO53830.1 - 9.9e-21 74.3 0.1 2.3e-20 73.1 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 AEO53830.1 - 2.1e-19 68.9 1.2 4.5e-19 67.8 0.4 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 AEO53830.1 - 8.1e-18 64.2 0.0 4.4e-17 61.8 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 AEO53830.1 - 2.5e-11 43.3 0.0 4.5e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 AEO53830.1 - 1.1e-10 41.0 1.1 1.3e-06 27.9 0.0 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.17 AEO53830.1 - 1.7e-07 30.7 0.1 3.4e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 AEO53830.1 - 3.1e-07 30.4 0.0 6.4e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 AEO53830.1 - 4.4e-07 29.5 0.0 1.5e-06 27.7 0.0 1.8 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_3 PF13437.1 AEO53830.1 - 0.00017 21.8 0.1 1.5 9.2 0.0 3.8 4 0 0 4 4 4 2 HlyD family secretion protein HlyD PF00529.15 AEO53830.1 - 0.00039 19.8 0.2 0.0051 16.1 0.0 2.5 2 0 0 2 2 2 1 HlyD family secretion protein HlyD_2 PF12700.2 AEO53830.1 - 0.0028 16.8 0.0 0.53 9.3 0.0 2.2 1 1 1 2 2 2 2 HlyD family secretion protein DUF2118 PF09891.4 AEO53830.1 - 0.036 13.7 0.1 0.11 12.1 0.1 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) Amidohydro_4 PF13147.1 AEO53830.1 - 0.11 12.4 2.1 5.3 6.9 0.0 3.6 2 2 1 4 4 4 0 Amidohydrolase GCV_H PF01597.14 AEO53830.1 - 0.18 11.4 0.4 1.9 8.2 0.1 2.4 1 1 1 2 2 2 0 Glycine cleavage H-protein YbjQ_1 PF01906.12 AEO53831.1 - 3.4e-29 101.3 0.3 4e-29 101.1 0.2 1.1 1 0 0 1 1 1 1 Putative heavy-metal-binding DPPIV_N PF00930.16 AEO53832.1 - 8.9e-109 363.2 0.1 1.2e-108 362.8 0.1 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 AEO53832.1 - 1e-50 171.9 1.0 2.3e-50 170.7 0.7 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 AEO53832.1 - 1.3e-08 34.7 0.3 8.2e-08 32.1 0.1 2.4 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AEO53832.1 - 0.00012 21.9 0.1 0.0044 16.9 0.0 2.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 AEO53832.1 - 0.0038 16.7 2.2 0.02 14.3 0.9 2.3 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PAF-AH_p_II PF03403.8 AEO53832.1 - 0.044 12.0 0.0 0.083 11.1 0.0 1.3 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Methyltransf_11 PF08241.7 AEO53833.1 - 1e-20 73.9 0.0 1.5e-18 67.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO53833.1 - 3e-18 65.8 0.0 4.3e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO53833.1 - 5.4e-13 48.9 0.0 8.8e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Sterol_MT_C PF08498.5 AEO53833.1 - 4.3e-10 39.4 0.0 6.4e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Ubie_methyltran PF01209.13 AEO53833.1 - 3.5e-09 36.1 0.0 5.1e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 AEO53833.1 - 1.3e-08 35.1 0.0 2.6e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO53833.1 - 2.9e-08 34.0 0.0 7.9e-08 32.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO53833.1 - 7.7e-08 32.9 0.0 1.4e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 AEO53833.1 - 1.4e-07 30.8 0.0 2e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 AEO53833.1 - 1.2e-05 25.2 0.0 2.9e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 AEO53833.1 - 0.0011 17.8 0.0 0.0017 17.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MetW PF07021.7 AEO53833.1 - 0.0015 17.8 0.0 0.003 16.9 0.0 1.5 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_8 PF05148.10 AEO53833.1 - 0.0039 16.8 0.0 0.056 13.0 0.0 2.0 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_15 PF09445.5 AEO53833.1 - 0.0057 16.2 0.0 0.0089 15.5 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PCMT PF01135.14 AEO53833.1 - 0.0093 15.5 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 AEO53833.1 - 0.078 12.6 0.0 0.21 11.2 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 AEO53833.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain UPF0020 PF01170.13 AEO53833.1 - 0.16 11.5 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 DUF2911 PF11138.3 AEO53834.1 - 0.064 12.8 0.3 0.11 12.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2911) Laminin_G_3 PF13385.1 AEO53834.1 - 0.25 11.5 4.9 0.55 10.4 3.4 1.7 1 1 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily PRA1 PF03208.14 AEO53835.1 - 9.7e-39 132.1 0.9 1.3e-38 131.7 0.6 1.1 1 0 0 1 1 1 1 PRA1 family protein DUF4282 PF14110.1 AEO53835.1 - 0.043 13.9 0.3 0.043 13.9 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) RILP PF11461.3 AEO53836.1 - 0.078 13.1 0.4 0.078 13.1 0.3 2.3 2 0 0 2 2 2 0 Rab interacting lysosomal protein IFRD_C PF04836.7 AEO53837.1 - 2.3 8.4 7.5 5.1 7.3 5.2 1.6 1 0 0 1 1 1 0 Interferon-related protein conserved region MFS_1 PF07690.11 AEO53840.1 - 5.3e-24 84.5 47.7 2e-21 76.0 17.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO53840.1 - 1.4e-10 40.4 25.5 5.5e-09 35.1 18.6 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 AEO53840.1 - 6e-05 21.4 0.8 0.00022 19.6 0.3 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PITH PF06201.8 AEO53842.1 - 4.7e-44 149.8 0.0 7e-44 149.2 0.0 1.3 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 AEO53842.1 - 8.8e-15 54.2 0.0 1.4e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin DUF3246 PF11596.3 AEO53842.1 - 0.00073 18.8 0.2 0.0011 18.3 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3246) Thioredoxin_2 PF13098.1 AEO53842.1 - 0.0019 18.3 0.0 0.0037 17.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain HyaE PF07449.6 AEO53842.1 - 0.032 14.1 0.0 0.062 13.2 0.0 1.5 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_6 PF13848.1 AEO53842.1 - 0.053 13.3 0.1 0.09 12.5 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_8 PF13905.1 AEO53842.1 - 0.082 13.0 0.1 0.95 9.6 0.0 2.2 1 1 1 2 2 2 0 Thioredoxin-like DUF1777 PF08648.7 AEO53845.1 - 6.5 6.4 25.7 0.053 13.2 7.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) RhoGAP PF00620.22 AEO53847.1 - 2.3e-44 150.6 0.2 1.1e-43 148.4 0.1 2.0 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.24 AEO53847.1 - 1.9e-11 44.0 0.0 4.4e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 AEO53847.1 - 4.2e-07 30.2 0.0 1.1e-06 28.8 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Golgin_A5 PF09787.4 AEO53847.1 - 0.0084 14.6 0.8 0.0084 14.6 0.5 3.3 4 0 0 4 4 4 1 Golgin subfamily A member 5 PH_8 PF15409.1 AEO53847.1 - 0.012 15.6 0.2 0.11 12.5 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain DUF3450 PF11932.3 AEO53847.1 - 0.013 14.7 3.0 0.032 13.5 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Zn_clus PF00172.13 AEO53848.1 - 5.8e-06 26.1 11.4 1e-05 25.3 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 AEO53848.1 - 2.1e-05 23.5 0.1 4.5e-05 22.4 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Mitofilin PF09731.4 AEO53850.1 - 5.9e-06 25.2 24.5 5.9e-06 25.2 16.9 2.0 2 0 0 2 2 2 1 Mitochondrial inner membrane protein SAPS PF04499.10 AEO53850.1 - 0.00065 18.4 16.0 0.0011 17.6 11.1 1.5 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein UPF0560 PF10577.4 AEO53850.1 - 0.041 12.1 11.0 0.12 10.5 7.6 1.8 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF262 PF03235.9 AEO53850.1 - 0.49 10.3 14.9 1.3 8.9 10.3 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF262 G-patch PF01585.18 AEO53851.1 - 4.2e-06 26.4 0.0 2.6e-05 23.9 0.0 2.4 1 1 0 1 1 1 1 G-patch domain CDC27 PF09507.5 AEO53851.1 - 0.067 12.4 63.9 0.095 11.9 44.3 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 MIP-T3 PF10243.4 AEO53851.1 - 0.79 8.1 76.8 1.2 7.5 53.2 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 TFIIF_alpha PF05793.7 AEO53851.1 - 0.86 7.8 61.3 1.4 7.1 42.5 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) COX17 PF05051.8 AEO53853.1 - 1.6e-20 72.8 6.4 2.1e-20 72.4 4.5 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Telomere_reg-2 PF10193.4 AEO53854.1 - 7.6e-41 138.9 0.0 1.7e-40 137.8 0.0 1.7 1 0 0 1 1 1 1 Telomere length regulation protein ThiF PF00899.16 AEO53855.1 - 2.6e-39 134.1 1.1 3.6e-39 133.6 0.2 1.6 2 0 0 2 2 2 1 ThiF family E2_bind PF08825.5 AEO53855.1 - 4.8e-30 103.1 0.0 8.2e-30 102.4 0.0 1.4 1 0 0 1 1 1 1 E2 binding domain UBACT PF02134.16 AEO53855.1 - 4.8e-24 83.7 0.4 1.3e-23 82.2 0.1 1.8 2 0 0 2 2 2 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 AEO53855.1 - 1.9e-15 55.9 1.6 4.3e-15 54.8 1.1 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 AEO53855.1 - 2e-05 24.5 0.0 0.00018 21.5 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Shikimate_DH PF01488.15 AEO53855.1 - 0.00063 19.8 0.1 0.0013 18.8 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 AEO53855.1 - 0.024 13.5 0.0 0.047 12.5 0.0 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase Ecm33 PF12454.3 AEO53855.1 - 0.03 14.2 3.2 0.063 13.1 2.3 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein MoeZ_MoeB PF05237.8 AEO53855.1 - 0.031 13.8 0.1 0.095 12.3 0.0 1.8 2 0 0 2 2 2 0 MoeZ/MoeB domain NAD_binding_7 PF13241.1 AEO53855.1 - 0.037 14.2 0.3 0.089 13.0 0.1 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding RNA_pol_A_bac PF01000.21 AEO53856.1 - 5.9e-27 94.0 0.0 1.2e-26 93.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 AEO53856.1 - 7.5e-11 40.9 0.0 9.8e-11 40.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain HeLo PF14479.1 AEO53857.1 - 2.7e-18 66.5 0.1 3.3e-18 66.2 0.1 1.0 1 0 0 1 1 1 1 Prion-inhibition and propagation Complex1_49kDa PF00346.14 AEO53858.1 - 9.7e-135 447.8 0.0 1.3e-134 447.4 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit DUF605 PF04652.11 AEO53859.1 - 4.8 6.4 17.7 0.27 10.6 8.4 1.9 2 0 0 2 2 2 0 Vta1 like FAD_binding_3 PF01494.14 AEO53860.1 - 2.2e-23 82.8 0.1 4.6e-21 75.2 0.1 2.2 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 AEO53860.1 - 1.3e-06 27.6 0.2 5.7e-05 22.1 0.1 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 AEO53860.1 - 5.5e-05 22.2 0.7 0.0018 17.3 0.1 2.8 2 1 0 2 2 2 1 Lycopene cyclase protein SE PF08491.5 AEO53860.1 - 0.0007 18.5 0.0 0.0011 17.8 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase NAD_binding_9 PF13454.1 AEO53860.1 - 0.0013 18.4 0.0 0.0033 17.2 0.0 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 AEO53860.1 - 0.0021 17.9 0.0 0.0043 16.9 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 AEO53860.1 - 0.055 12.3 0.0 0.094 11.6 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 AEO53860.1 - 0.14 11.1 0.0 0.37 9.8 0.0 1.7 2 0 0 2 2 2 0 Thi4 family HEAT PF02985.17 AEO53861.1 - 0.034 14.2 0.1 0.072 13.2 0.0 1.6 1 0 0 1 1 1 0 HEAT repeat Pkinase PF00069.20 AEO53863.1 - 1.6e-55 188.0 0.0 2.5e-55 187.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO53863.1 - 6.5e-41 140.1 0.0 1e-40 139.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO53863.1 - 0.0026 16.7 0.0 0.0065 15.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 AEO53863.1 - 0.039 13.0 0.3 0.11 11.5 0.0 1.9 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Apis_Csd PF11671.3 AEO53863.1 - 0.37 10.5 6.7 1.1 9.0 4.7 1.7 1 0 0 1 1 1 0 Complementary sex determiner protein Sua5_yciO_yrdC PF01300.13 AEO53864.1 - 6.8e-51 172.0 0.0 2.1e-30 105.2 0.0 2.3 2 0 0 2 2 2 2 Telomere recombination SUA5 PF03481.8 AEO53864.1 - 1.8e-24 86.1 0.0 4.9e-24 84.8 0.0 1.7 1 1 0 1 1 1 1 Putative GTP-binding controlling metal-binding Mito_fiss_reg PF05308.6 AEO53864.1 - 0.28 10.5 8.4 0.52 9.6 5.8 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 AEO53864.1 - 0.5 9.6 6.8 0.88 8.7 4.7 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal MSP1_C PF07462.6 AEO53864.1 - 0.73 8.1 2.3 1.1 7.5 1.6 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF2486 PF10667.4 AEO53864.1 - 3.1 8.2 8.7 0.18 12.3 1.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2486) DUF3439 PF11921.3 AEO53864.1 - 4.9 6.9 11.0 12 5.6 7.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Clat_adaptor_s PF01217.15 AEO53865.1 - 9.1e-15 54.6 0.0 2.1e-12 46.9 0.1 2.1 2 0 0 2 2 2 2 Clathrin adaptor complex small chain MCM PF00493.18 AEO53866.1 - 2.1e-141 470.5 0.0 2.9e-141 470.0 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 AEO53866.1 - 4.9e-26 91.5 0.3 2.1e-25 89.5 0.0 2.3 3 0 0 3 3 3 1 MCM N-terminal domain AAA_5 PF07728.9 AEO53866.1 - 1e-05 25.2 0.1 5e-05 23.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 AEO53866.1 - 1.4e-05 24.3 0.0 0.00025 20.2 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 AEO53866.1 - 0.0032 17.0 0.0 0.013 15.1 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Elf1 PF05129.8 AEO53866.1 - 0.17 11.6 2.6 0.22 11.2 0.9 1.8 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Pil1 PF13805.1 AEO53867.1 - 3.8e-113 377.1 1.8 4.6e-113 376.8 1.2 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 Ribophorin_I PF04597.9 AEO53868.1 - 7.9e-156 518.8 0.1 9.1e-156 518.7 0.1 1.0 1 0 0 1 1 1 1 Ribophorin I UL73_N PF12522.3 AEO53868.1 - 0.22 11.0 6.6 0.46 10.0 4.6 1.5 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein N terminal Hexokinase_2 PF03727.11 AEO53869.1 - 1.8e-87 292.6 0.0 2.5e-87 292.1 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 AEO53869.1 - 1.4e-76 256.3 0.0 8.5e-75 250.6 0.0 2.1 2 0 0 2 2 2 2 Hexokinase FGGY_N PF00370.16 AEO53869.1 - 0.013 14.8 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain PhnJ PF06007.6 AEO53869.1 - 0.11 11.2 0.0 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnJ Cys_Met_Meta_PP PF01053.15 AEO53870.1 - 1.2e-19 69.8 0.0 1.2e-13 50.1 0.0 2.1 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 AEO53870.1 - 0.026 13.5 0.0 0.045 12.7 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II VTC PF09359.5 AEO53871.1 - 3e-101 338.1 0.0 4.8e-101 337.4 0.0 1.3 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 AEO53871.1 - 4e-27 95.6 1.7 1e-12 48.4 0.2 3.1 2 1 1 3 3 3 2 SPX domain DUF202 PF02656.10 AEO53871.1 - 4.9e-12 45.9 2.5 1.3e-11 44.5 1.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF202) TrmB PF01978.14 AEO53871.1 - 0.0023 17.6 0.3 0.03 14.0 0.1 2.6 3 0 0 3 3 3 1 Sugar-specific transcriptional regulator TrmB HTH_29 PF13551.1 AEO53871.1 - 0.021 14.9 0.0 0.14 12.3 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn helix Fe_dep_repress PF01325.14 AEO53871.1 - 0.074 13.0 0.1 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain PBP1_TM PF14812.1 AEO53871.1 - 5.6 7.3 15.2 1.1 9.5 3.5 3.0 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.5 AEO53871.1 - 7.5 6.8 13.2 0.16 12.2 2.5 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Ank_2 PF12796.2 AEO53872.1 - 1.3e-06 28.6 0.0 3.6e-06 27.2 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 AEO53872.1 - 0.034 13.9 0.1 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeat MYCBPAP PF14646.1 AEO53872.1 - 0.043 12.5 0.1 0.059 12.0 0.1 1.1 1 0 0 1 1 1 0 MYCBP-associated protein family Ank_5 PF13857.1 AEO53872.1 - 0.21 11.8 2.1 1.3 9.4 0.1 3.0 3 1 1 4 4 4 0 Ankyrin repeats (many copies) Trypan_PARP PF05887.6 AEO53872.1 - 0.36 10.6 18.8 0.88 9.3 13.0 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) SDA1 PF05285.7 AEO53872.1 - 2.9 7.0 20.4 1.1 8.4 11.2 2.0 2 0 0 2 2 2 0 SDA1 CDC45 PF02724.9 AEO53872.1 - 6.5 4.6 6.5 8.5 4.2 4.5 1.1 1 0 0 1 1 1 0 CDC45-like protein AAA PF00004.24 AEO53873.1 - 2.1e-57 192.9 0.0 2.1e-43 147.6 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 AEO53873.1 - 1e-29 102.4 0.0 2.2e-29 101.3 0.0 1.6 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 AEO53873.1 - 2.9e-12 46.9 5.0 1.2e-06 28.5 0.1 4.4 3 1 1 4 4 4 2 AAA ATPase domain NACHT PF05729.7 AEO53873.1 - 2.7e-08 33.6 0.2 5.8e-05 22.7 0.0 3.5 3 0 0 3 3 3 1 NACHT domain AAA_2 PF07724.9 AEO53873.1 - 8.1e-07 29.1 0.0 0.015 15.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 AEO53873.1 - 8.7e-07 28.6 0.0 0.0048 16.6 0.0 3.4 2 0 0 2 2 2 2 Part of AAA domain AAA_22 PF13401.1 AEO53873.1 - 2.8e-06 27.5 0.8 0.074 13.1 0.1 3.9 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 AEO53873.1 - 5.1e-06 27.3 0.4 0.16 12.7 0.0 2.9 2 1 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 AEO53873.1 - 6.9e-06 25.5 0.1 0.016 14.6 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 AEO53873.1 - 8.3e-06 25.8 0.0 0.0032 17.5 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain Zeta_toxin PF06414.7 AEO53873.1 - 9.4e-06 24.8 0.0 0.023 13.7 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_33 PF13671.1 AEO53873.1 - 1.3e-05 25.1 0.1 0.22 11.3 0.1 2.9 2 1 0 2 2 2 2 AAA domain AAA_14 PF13173.1 AEO53873.1 - 2.9e-05 23.9 0.0 0.26 11.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.7 AEO53873.1 - 3.9e-05 22.8 0.0 0.013 14.5 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 AEO53873.1 - 4.2e-05 23.2 0.1 0.21 11.3 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 AEO53873.1 - 0.00035 20.8 0.7 0.23 11.7 0.1 2.9 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.17 AEO53873.1 - 0.00072 18.5 0.1 0.18 10.5 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain TIP49 PF06068.8 AEO53873.1 - 0.00083 18.1 0.0 0.91 8.1 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_25 PF13481.1 AEO53873.1 - 0.0011 18.4 3.7 1.7 7.9 0.2 4.3 2 2 2 4 4 4 1 AAA domain AAA_28 PF13521.1 AEO53873.1 - 0.0015 18.5 0.1 0.48 10.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 AEO53873.1 - 0.0023 17.4 0.0 0.13 11.7 0.0 2.6 3 0 0 3 3 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 AEO53873.1 - 0.0038 16.4 0.1 0.7 9.0 0.0 2.6 3 0 0 3 3 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 AEO53873.1 - 0.005 16.9 0.0 4.3 7.5 0.0 2.7 2 0 0 2 2 2 0 RNA helicase DUF815 PF05673.8 AEO53873.1 - 0.0055 15.6 0.1 0.073 11.9 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_29 PF13555.1 AEO53873.1 - 0.0056 16.1 0.1 0.053 13.0 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain NTPase_1 PF03266.10 AEO53873.1 - 0.0063 16.2 0.1 0.11 12.1 0.0 2.2 2 0 0 2 2 2 1 NTPase UPF0079 PF02367.12 AEO53873.1 - 0.0075 15.8 0.0 0.19 11.3 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 KAP_NTPase PF07693.9 AEO53873.1 - 0.0076 15.2 0.1 0.57 9.1 0.0 2.5 1 1 1 2 2 2 1 KAP family P-loop domain ABC_tran PF00005.22 AEO53873.1 - 0.0085 16.3 0.0 3.5 7.9 0.0 2.8 2 0 0 2 2 2 1 ABC transporter Arch_ATPase PF01637.13 AEO53873.1 - 0.012 15.3 0.0 1.8 8.1 0.0 3.0 2 1 1 3 3 3 0 Archaeal ATPase KaiC PF06745.8 AEO53873.1 - 0.02 13.9 0.2 5 6.1 0.0 2.5 2 0 0 2 2 2 0 KaiC KTI12 PF08433.5 AEO53873.1 - 0.026 13.7 0.0 0.16 11.1 0.0 2.1 2 0 0 2 2 2 0 Chromatin associated protein KTI12 T2SE PF00437.15 AEO53873.1 - 0.037 12.9 0.4 0.16 10.8 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF2075 PF09848.4 AEO53873.1 - 0.044 12.7 0.0 7.1 5.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.13 AEO53873.1 - 0.046 13.2 0.1 0.21 11.0 0.0 2.1 3 0 0 3 3 2 0 FtsK/SpoIIIE family APS_kinase PF01583.15 AEO53873.1 - 0.046 13.3 0.2 0.23 11.1 0.0 2.1 2 0 0 2 2 2 0 Adenylylsulphate kinase MobB PF03205.9 AEO53873.1 - 0.054 13.1 0.0 0.17 11.5 0.0 1.9 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.13 AEO53873.1 - 0.14 11.7 0.0 3.7 7.0 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.1 AEO53873.1 - 0.14 11.7 0.5 6.9 6.1 0.2 2.6 3 0 0 3 3 2 0 AAA domain PRK PF00485.13 AEO53873.1 - 0.28 10.7 0.1 1.6 8.2 0.0 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family TrwB_AAD_bind PF10412.4 AEO53873.1 - 0.37 9.3 1.3 1.1 7.7 0.1 2.2 2 1 1 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain MCM PF00493.18 AEO53874.1 - 5.8e-133 442.7 0.0 1.1e-132 441.9 0.0 1.4 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 AEO53874.1 - 1.8e-28 99.4 1.1 8.1e-28 97.3 0.7 2.1 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 AEO53874.1 - 1.9e-07 30.4 0.0 1.4e-05 24.3 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 AEO53874.1 - 2e-06 27.5 0.0 7.8e-06 25.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 AEO53874.1 - 0.037 13.6 0.0 0.13 11.9 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DAP3 PF10236.4 AEO53875.1 - 6e-96 321.0 0.0 7.6e-96 320.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.1 AEO53875.1 - 0.023 14.6 0.1 0.1 12.5 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain RRS1 PF04939.7 AEO53876.1 - 2.4e-55 186.4 0.3 2.8e-55 186.2 0.2 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) RhoGAP PF00620.22 AEO53877.1 - 2.1e-29 102.0 0.0 3.6e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Prenyltrans PF00432.16 AEO53878.1 - 2.3e-54 180.5 7.6 3.2e-11 42.6 0.0 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 AEO53878.1 - 1.1e-36 125.6 0.0 5.1e-14 52.6 0.0 3.9 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 AEO53878.1 - 2.1e-10 40.5 0.0 7.2e-05 22.7 0.0 2.6 1 1 1 2 2 2 2 Prenyltransferase-like CHASE4 PF05228.8 AEO53879.1 - 0.045 13.3 0.1 0.086 12.4 0.1 1.4 1 0 0 1 1 1 0 CHASE4 domain zf-C2H2 PF00096.21 AEO53879.1 - 2.4 8.6 5.0 0.85 10.0 1.0 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type MutS_V PF00488.16 AEO53880.1 - 2e-77 259.8 0.0 5.1e-77 258.4 0.0 1.7 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.13 AEO53880.1 - 1.4e-37 129.4 1.0 2.4e-37 128.7 0.7 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 AEO53880.1 - 3.1e-29 101.2 0.0 6.6e-29 100.2 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 AEO53880.1 - 1.2e-09 38.3 0.0 2.9e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 AEO53880.1 - 6e-06 26.3 0.0 1.5e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV Sugar_tr PF00083.19 AEO53881.1 - 3.8e-83 279.5 14.8 4.3e-83 279.3 10.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO53881.1 - 4.9e-30 104.4 41.1 9.8e-28 96.8 14.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 AEO53881.1 - 8.2e-05 20.9 6.1 0.00016 20.0 0.6 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 AEO53881.1 - 0.00016 19.8 0.5 0.00031 18.9 0.2 1.5 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.1 AEO53881.1 - 0.00053 18.4 3.2 0.00053 18.4 2.2 3.3 2 1 1 3 3 3 2 MFS/sugar transport protein Complex1_LYR PF05347.10 AEO53883.1 - 1.4e-15 56.8 4.5 1.7e-15 56.5 3.1 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 AEO53883.1 - 9e-13 48.2 4.2 1e-12 48.0 2.9 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Vicilin_N PF04702.7 AEO53883.1 - 0.0031 17.1 1.4 0.0035 16.9 1.0 1.1 1 0 0 1 1 1 1 Vicilin N terminal region EVC2_like PF12297.3 AEO53883.1 - 0.058 12.0 0.5 0.067 11.8 0.4 1.0 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein FAA_hydrolase PF01557.13 AEO53884.1 - 1.9e-66 223.6 0.0 2.5e-66 223.2 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF3602 PF12223.3 AEO53885.1 - 1.7e-14 53.9 12.2 1.7e-13 50.7 3.4 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) ATG22 PF11700.3 AEO53887.1 - 0.00025 19.6 1.5 0.00033 19.2 1.0 1.1 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like DUF1517 PF07466.6 AEO53887.1 - 1.4 7.8 4.1 1.9 7.3 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) SR-25 PF10500.4 AEO53887.1 - 5.7 6.3 8.0 7.4 5.9 5.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ATG22 PF11700.3 AEO53888.1 - 5.4e-167 556.0 18.2 6.1e-167 555.8 12.6 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like DUF1469 PF07332.6 AEO53888.1 - 0.28 10.8 0.0 0.28 10.8 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) BAH PF01426.13 AEO53889.1 - 2.3e-05 24.1 0.1 4.1e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 BAH domain PHD PF00628.24 AEO53889.1 - 0.0046 16.6 1.7 0.012 15.3 1.2 1.7 1 0 0 1 1 1 1 PHD-finger Spt20 PF12090.3 AEO53889.1 - 0.22 10.8 4.9 0.45 9.8 3.4 1.5 1 0 0 1 1 1 0 Spt20 family Herpes_TAF50 PF03326.8 AEO53889.1 - 0.58 9.0 16.9 0.93 8.3 11.7 1.2 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) RRF PF01765.14 AEO53890.1 - 5.5e-24 84.4 0.0 5.5e-24 84.4 0.0 1.7 2 0 0 2 2 2 1 Ribosome recycling factor Pox_Ag35 PF03286.9 AEO53890.1 - 0.0058 16.1 1.6 0.0094 15.4 1.1 1.3 1 0 0 1 1 1 1 Pox virus Ag35 surface protein Peripla_BP_1 PF00532.16 AEO53890.1 - 0.056 12.6 0.0 2.6 7.1 0.0 2.2 2 0 0 2 2 2 0 Periplasmic binding proteins and sugar binding domain of LacI family CDC45 PF02724.9 AEO53890.1 - 0.84 7.6 5.3 1.2 7.0 3.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Wbp11 PF09429.5 AEO53890.1 - 1.2 9.1 10.8 0.62 10.0 0.9 2.7 2 0 0 2 2 2 0 WW domain binding protein 11 Sigma70_ner PF04546.8 AEO53890.1 - 2.5 7.6 7.7 0.38 10.3 2.3 1.8 2 0 0 2 2 2 0 Sigma-70, non-essential region LCD1 PF09798.4 AEO53891.1 - 0.71 7.7 4.5 0.98 7.3 3.1 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein Glyco_hydro_3 PF00933.16 AEO53892.1 - 4.5e-86 288.5 0.0 6.3e-86 288.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 AEO53892.1 - 2.3e-73 246.4 0.0 2e-72 243.3 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 AEO53892.1 - 8e-24 83.3 0.2 1.7e-23 82.3 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 AEO53892.1 - 7.5e-20 71.0 0.0 1.3e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 PA14 domain PP1_bind PF15276.1 AEO53892.1 - 0.029 14.3 0.3 0.088 12.8 0.2 1.8 1 0 0 1 1 1 0 Protein phosphatase 1 binding Metallophos PF00149.23 AEO53893.1 - 5.2e-15 55.3 3.8 6.6e-14 51.7 2.7 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase UDG PF03167.14 AEO53894.1 - 1.4e-24 86.2 0.0 2.4e-24 85.5 0.0 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Lectin_legB PF00139.14 AEO53894.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Legume lectin domain CDC27 PF09507.5 AEO53894.1 - 9.1 5.3 14.6 0.12 11.5 0.3 2.1 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 DUF1708 PF08101.6 AEO53895.1 - 1.2e-63 215.4 0.0 1.7e-63 214.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) Mito_carr PF00153.22 AEO53896.1 - 5e-47 157.5 1.0 2.2e-20 72.1 0.0 4.3 3 1 1 4 4 4 4 Mitochondrial carrier protein DUF3720 PF12517.3 AEO53896.1 - 0.16 12.7 3.4 0.48 11.1 2.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3720) SR-25 PF10500.4 AEO53896.1 - 0.67 9.3 6.0 1.1 8.6 4.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3665 PF12427.3 AEO53898.1 - 0.08 12.3 0.1 0.2 11.0 0.0 1.7 1 0 0 1 1 1 0 Branched-chain amino acid aminotransferase DUF1970 PF09301.5 AEO53898.1 - 0.13 12.3 0.1 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1970) Glyco_transf_28 PF03033.15 AEO53899.1 - 1.2e-20 73.7 0.2 1.9e-13 50.3 0.0 2.8 3 0 0 3 3 3 2 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 AEO53899.1 - 7.6e-06 24.7 0.3 7.6e-06 24.7 0.2 1.7 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 AEO53899.1 - 0.00023 20.8 0.0 0.00023 20.8 0.0 2.6 2 1 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain Mito_carr PF00153.22 AEO53900.1 - 5.1e-52 173.5 9.2 2.3e-19 68.8 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Spindle_Spc25 PF08234.7 AEO53901.1 - 0.051 13.5 0.0 0.099 12.6 0.0 1.5 1 0 0 1 1 1 0 Chromosome segregation protein Spc25 Epimerase PF01370.16 AEO53903.1 - 1.7e-20 73.4 0.0 2.4e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 AEO53903.1 - 6.4e-08 31.8 0.0 1.1e-07 31.1 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 AEO53903.1 - 4.4e-05 23.4 0.0 0.00015 21.7 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 AEO53903.1 - 0.00066 19.7 0.1 0.003 17.5 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 AEO53903.1 - 0.017 13.8 0.0 0.043 12.5 0.0 1.8 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 AEO53903.1 - 0.043 12.7 0.0 0.074 11.9 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein Saccharop_dh PF03435.13 AEO53903.1 - 0.051 12.5 0.0 0.07 12.0 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Ldh_1_N PF00056.18 AEO53903.1 - 0.11 12.2 0.1 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain F_actin_cap_B PF01115.12 AEO53904.1 - 8.4e-109 362.3 0.0 9.9e-109 362.1 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Glyco_transf_22 PF03901.12 AEO53905.1 - 6.5e-42 143.9 14.9 8.9e-42 143.5 10.3 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PMT_2 PF13231.1 AEO53905.1 - 1.4 8.8 27.1 0.92 9.3 11.7 2.6 2 0 0 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase Metallophos PF00149.23 AEO53906.1 - 1.8e-39 135.2 0.2 2.4e-39 134.8 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SUR7 PF06687.7 AEO53907.1 - 1.1e-37 129.7 8.6 1.3e-37 129.4 6.0 1.1 1 0 0 1 1 1 1 SUR7/PalI family E1-E2_ATPase PF00122.15 AEO53907.1 - 0.01 14.8 0.8 0.16 10.9 0.9 2.2 2 0 0 2 2 2 0 E1-E2 ATPase Claudin_2 PF13903.1 AEO53907.1 - 0.36 10.5 19.7 0.077 12.6 8.6 2.7 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction WD40 PF00400.27 AEO53908.1 - 1.3e-16 59.7 4.0 0.0041 16.9 0.0 9.7 11 0 0 11 11 11 4 WD domain, G-beta repeat SET PF00856.23 AEO53909.1 - 3e-22 79.6 0.6 3e-22 79.6 0.4 3.2 3 1 0 3 3 3 1 SET domain PAT1 PF09770.4 AEO53910.1 - 0.52 8.4 16.1 0.6 8.2 11.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 AEO53910.1 - 1.1 8.5 22.0 1.4 8.2 15.3 1.1 1 0 0 1 1 1 0 Vta1 like TFIIA PF03153.8 AEO53910.1 - 1.6 8.5 14.9 1.9 8.3 10.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pil1 PF13805.1 AEO53911.1 - 5e-155 514.4 0.4 6.1e-155 514.1 0.3 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.6 AEO53911.1 - 0.067 12.5 4.4 0.26 10.6 3.0 1.9 1 1 0 1 1 1 0 FAM92 protein LSM PF01423.17 AEO53912.1 - 7.1e-07 28.6 0.0 1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 LSM domain K_channel_TID PF07941.6 AEO53912.1 - 0.01 16.0 3.1 0.023 14.9 2.2 1.5 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain SM-ATX PF14438.1 AEO53912.1 - 0.032 14.1 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 Ataxin 2 SM domain XPG_N PF00752.12 AEO53913.1 - 8.8e-33 112.5 0.0 2.1e-32 111.3 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 AEO53913.1 - 5.9e-27 93.5 0.0 1.4e-26 92.3 0.0 1.7 1 0 0 1 1 1 1 XPG I-region UIM PF02809.15 AEO53913.1 - 0.0052 16.2 2.7 0.0052 16.2 1.9 3.7 3 0 0 3 3 3 1 Ubiquitin interaction motif RR_TM4-6 PF06459.7 AEO53913.1 - 0.023 14.5 0.1 0.023 14.5 0.1 4.8 4 1 2 6 6 6 0 Ryanodine Receptor TM 4-6 HHH PF00633.18 AEO53913.1 - 0.11 12.2 0.5 0.37 10.5 0.1 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix motif BTB PF00651.26 AEO53915.1 - 0.12 12.3 0.0 0.3 11.0 0.0 1.7 1 1 0 1 1 1 0 BTB/POZ domain Oxidored_FMN PF00724.15 AEO53916.1 - 1.5e-67 228.0 0.0 2.5e-65 220.7 0.0 2.1 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Peptidase_C15 PF01470.12 AEO53917.1 - 6.9e-06 26.0 0.0 8e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Pyroglutamyl peptidase Glyco_transf_17 PF04724.8 AEO53918.1 - 1.8e-49 168.6 0.0 2.7e-49 168.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 17 SLT_2 PF13406.1 AEO53918.1 - 0.13 11.1 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Transglycosylase SLT domain Lum_binding PF00677.12 AEO53919.1 - 4.9e-37 125.6 0.0 2.2e-20 72.3 0.0 2.1 2 0 0 2 2 2 2 Lumazine binding domain ERCC4 PF02732.10 AEO53920.1 - 2.3e-32 111.6 0.1 3.5e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.1 AEO53920.1 - 0.00029 20.9 0.0 0.00068 19.7 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain PGM_PMM_I PF02878.11 AEO53921.1 - 4.1e-18 65.2 0.1 1.3e-07 31.1 0.0 2.8 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 AEO53921.1 - 1.7e-13 50.7 0.2 1.1e-12 48.1 0.1 2.5 2 1 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 AEO53921.1 - 1.8e-10 40.6 0.6 4.6e-10 39.3 0.4 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 AEO53921.1 - 0.047 13.7 0.0 0.17 11.9 0.0 2.0 1 1 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Methyltransf_31 PF13847.1 AEO53923.1 - 1.6e-12 47.2 0.1 2.5e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 AEO53923.1 - 1.5e-11 43.9 0.0 2e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PrmA PF06325.8 AEO53923.1 - 3e-11 43.0 0.0 4.3e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 AEO53923.1 - 4.8e-10 40.0 0.0 1.3e-09 38.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO53923.1 - 2.5e-08 33.9 0.0 5.6e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO53923.1 - 2.9e-08 34.0 0.0 6.3e-08 33.0 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 AEO53923.1 - 5.6e-07 28.5 0.0 8.7e-07 27.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.1 AEO53923.1 - 8.4e-07 29.3 0.0 1.9e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO53923.1 - 5e-06 26.3 0.0 1.3e-05 24.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 AEO53923.1 - 9.5e-06 25.0 0.0 1.5e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 AEO53923.1 - 0.00015 21.8 0.0 0.00022 21.2 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_12 PF08242.7 AEO53923.1 - 0.00029 21.2 0.0 0.00052 20.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 AEO53923.1 - 0.00032 19.8 0.0 0.00046 19.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Met_10 PF02475.11 AEO53923.1 - 0.0091 15.6 0.1 0.014 15.0 0.1 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_16 PF10294.4 AEO53923.1 - 0.011 15.2 0.1 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase PCMT PF01135.14 AEO53923.1 - 0.013 15.0 0.1 0.021 14.3 0.1 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.13 AEO53923.1 - 0.016 14.7 0.1 0.027 14.0 0.1 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_32 PF13679.1 AEO53923.1 - 0.02 14.5 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 AEO53923.1 - 0.035 13.1 0.0 0.062 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase TehB PF03848.9 AEO53923.1 - 0.036 13.2 0.0 0.077 12.1 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TehB DOT1 PF08123.8 AEO53923.1 - 0.037 13.3 0.1 0.059 12.6 0.1 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Ubie_methyltran PF01209.13 AEO53923.1 - 0.056 12.5 0.2 0.12 11.4 0.1 1.5 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family Cons_hypoth95 PF03602.10 AEO53923.1 - 0.064 12.6 0.0 0.095 12.0 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Mob1_phocein PF03637.12 AEO53924.1 - 2.8e-38 131.3 2.8 8.1e-21 74.4 0.1 2.1 2 0 0 2 2 2 2 Mob1/phocein family DNA_pol_B_palm PF14792.1 AEO53925.1 - 3.5e-28 97.8 0.0 6.9e-28 96.9 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 AEO53925.1 - 1.1e-22 79.4 0.1 3.4e-22 77.8 0.1 1.9 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.4 AEO53925.1 - 4.2e-20 71.0 0.0 8.3e-20 70.0 0.0 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.1 AEO53925.1 - 4.5e-18 65.2 0.1 1.3e-17 63.7 0.1 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain SSFA2_C PF14723.1 AEO53925.1 - 0.051 13.3 0.6 0.14 11.8 0.4 1.8 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus NTP_transf_2 PF01909.18 AEO53925.1 - 0.12 12.6 0.0 0.34 11.2 0.0 1.7 1 0 0 1 1 1 0 Nucleotidyltransferase domain DNA_pol_phi PF04931.8 AEO53925.1 - 0.56 7.9 3.2 0.87 7.2 2.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi VPS9 PF02204.13 AEO53927.1 - 2.2e-19 69.4 0.0 4.1e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.1 AEO53927.1 - 1.1e-15 57.3 0.1 7e-11 42.0 0.0 5.7 6 1 1 7 7 7 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 AEO53927.1 - 1.1e-09 38.4 0.1 0.00081 19.8 0.0 5.1 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 AEO53927.1 - 1.5e-09 38.0 0.0 0.00026 21.2 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 AEO53927.1 - 3.8e-06 26.6 0.1 2.1 8.8 0.0 5.5 6 0 0 6 6 6 2 Ankyrin repeat PX PF00787.19 AEO53927.1 - 1.8e-05 24.4 0.1 5.9e-05 22.8 0.1 1.9 1 0 0 1 1 1 1 PX domain Ank PF00023.25 AEO53927.1 - 0.00013 21.5 1.8 0.0078 15.9 0.0 4.1 4 1 0 4 4 4 1 Ankyrin repeat YchF-GTPase_C PF06071.8 AEO53928.1 - 1.1e-33 114.8 0.4 3.4e-33 113.2 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 AEO53928.1 - 2.5e-12 46.7 0.0 4.4e-12 45.9 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AEO53928.1 - 0.00043 19.6 0.0 0.00084 18.6 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.16 AEO53928.1 - 0.0032 17.2 0.1 0.01 15.6 0.0 1.9 1 0 0 1 1 1 1 TGS domain MobB PF03205.9 AEO53928.1 - 0.028 14.1 0.3 4 7.1 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 AEO53928.1 - 0.049 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 AEO53928.1 - 0.057 13.7 0.1 3.5 7.9 0.0 2.6 3 0 0 3 3 3 0 ABC transporter PPAK PF02818.10 AEO53928.1 - 0.31 10.9 4.5 0.093 12.6 0.7 2.0 2 0 0 2 2 2 0 PPAK motif Peptidase_C97 PF05903.9 AEO53929.1 - 3.3e-32 111.3 0.0 4.1e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 AEO53929.1 - 0.00023 21.1 0.0 0.00039 20.3 0.0 1.3 1 0 0 1 1 1 1 Lecithin retinol acyltransferase Defensin_4 PF07936.7 AEO53929.1 - 0.054 13.1 1.9 0.12 12.0 1.3 1.5 1 0 0 1 1 1 0 Potassium-channel blocking toxin 3Beta_HSD PF01073.14 AEO53930.1 - 5e-17 61.4 0.0 1.3e-16 60.1 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 AEO53930.1 - 1.8e-13 50.5 0.0 2.5e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 AEO53930.1 - 3.3e-08 32.7 0.1 1.1e-07 31.1 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 AEO53930.1 - 8.4e-07 29.0 1.2 2.9e-06 27.3 0.9 1.9 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 AEO53930.1 - 8.4e-07 29.1 0.0 7e-06 26.1 0.0 2.4 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 AEO53930.1 - 8.4e-05 22.2 0.4 0.0002 21.0 0.3 1.6 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 AEO53930.1 - 0.046 12.6 0.0 0.073 11.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TrkA_N PF02254.13 AEO53930.1 - 0.053 13.5 0.0 0.18 11.8 0.0 1.8 1 1 0 1 1 1 0 TrkA-N domain DUF3933 PF13069.1 AEO53930.1 - 0.12 12.0 0.0 0.41 10.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3933) CDK2AP PF09806.4 AEO53931.1 - 0.4 10.8 6.7 0.67 10.1 4.6 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein FIVAR PF07554.8 AEO53933.1 - 0.085 13.1 0.4 9.6 6.5 0.2 2.7 2 0 0 2 2 2 0 Uncharacterised Sugar-binding Domain Filament PF00038.16 AEO53933.1 - 0.21 11.0 93.3 0.073 12.5 22.3 6.7 4 2 1 5 5 5 0 Intermediate filament protein SAS4 PF15460.1 AEO53934.1 - 9.8e-35 118.4 0.1 9.8e-35 118.4 0.1 2.0 2 0 0 2 2 2 1 Something about silencing, SAS, complex subunit 4 CamS PF07537.6 AEO53934.1 - 0.076 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 CamS sex pheromone cAM373 precursor Peptidase_M1 PF01433.15 AEO53936.1 - 5.4e-08 32.3 0.0 0.043 12.9 0.0 3.3 3 0 0 3 3 3 3 Peptidase family M1 APC_CDC26 PF10471.4 AEO53937.1 - 1.1e-11 45.2 0.5 1.1e-11 45.2 0.3 3.5 3 1 0 3 3 3 1 Anaphase-promoting complex APC subunit 1 DUF1510 PF07423.6 AEO53937.1 - 0.045 13.1 5.9 0.077 12.3 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) PepSY PF03413.14 AEO53937.1 - 0.35 11.5 2.7 0.68 10.6 0.4 2.3 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Nop14 PF04147.7 AEO53937.1 - 3.5 5.4 13.3 4.3 5.1 9.2 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 AEO53937.1 - 5.1 5.0 7.8 7.9 4.3 5.4 1.4 1 0 0 1 1 1 0 CDC45-like protein WLM PF08325.5 AEO53938.1 - 2.3e-47 161.2 0.0 2.9e-47 160.9 0.0 1.2 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.13 AEO53938.1 - 5.8e-08 31.7 5.6 5.8e-08 31.7 3.9 3.4 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others SprT-like PF10263.4 AEO53938.1 - 0.00042 20.0 2.1 0.00059 19.5 0.0 2.1 2 1 0 2 2 2 1 SprT-like family DUF45 PF01863.12 AEO53938.1 - 0.00048 19.9 0.2 0.00097 18.9 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 Lem_TRP PF08262.6 AEO53938.1 - 0.0093 15.6 0.1 0.024 14.3 0.1 1.7 1 0 0 1 1 1 1 Leucophaea maderae tachykinin-related peptide RecR PF02132.10 AEO53938.1 - 0.23 10.9 0.1 0.23 10.9 0.1 2.6 2 1 0 2 2 2 0 RecR protein DZR PF12773.2 AEO53938.1 - 0.41 10.5 10.0 2 8.3 7.0 2.0 1 1 0 1 1 1 0 Double zinc ribbon zf-Sec23_Sec24 PF04810.10 AEO53938.1 - 1.1 8.8 24.2 0.65 9.5 1.0 3.7 2 2 1 3 3 3 0 Sec23/Sec24 zinc finger Asp PF00026.18 AEO53939.1 - 1.3e-68 231.6 0.1 1.5e-68 231.4 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 AEO53939.1 - 9.1e-06 25.7 0.3 1.6e-05 24.9 0.2 1.4 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 AEO53939.1 - 4.7e-05 23.8 0.1 0.03 14.7 0.0 3.5 3 1 0 3 3 3 1 Aspartyl protease TAXi_C PF14541.1 AEO53939.1 - 0.023 14.2 0.0 0.078 12.5 0.0 1.9 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal Aldedh PF00171.17 AEO53941.1 - 9.2e-134 446.2 0.0 1.1e-133 445.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Response_reg PF00072.19 AEO53943.1 - 2.3e-13 50.0 0.0 4.6e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 AEO53943.1 - 1.8e-09 37.3 0.0 3.2e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Lzipper-MIP1 PF14389.1 AEO53944.1 - 0.076 13.1 0.8 0.15 12.2 0.1 1.9 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 SlyX PF04102.7 AEO53944.1 - 0.12 12.8 0.3 9.7 6.6 0.0 2.8 2 0 0 2 2 2 0 SlyX ATG16 PF08614.6 AEO53944.1 - 0.17 11.6 2.8 0.12 12.2 0.2 1.9 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) AAA_11 PF13086.1 AEO53945.1 - 1.3e-58 198.3 0.0 4.1e-58 196.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 AEO53945.1 - 9.2e-56 188.3 0.0 2.7e-55 186.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 AEO53945.1 - 1.6e-12 47.0 0.3 1.2e-11 44.1 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 AEO53945.1 - 3.5e-09 36.5 0.0 2.4e-07 30.5 0.0 2.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 AEO53945.1 - 2.2e-07 30.8 0.0 5.9e-07 29.5 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 AEO53945.1 - 7e-07 29.0 0.0 0.19 11.1 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 AEO53945.1 - 7.5e-06 25.1 0.1 5.4e-05 22.3 0.0 2.2 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 AEO53945.1 - 4.2e-05 23.6 0.0 0.0014 18.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain UvrD-helicase PF00580.16 AEO53945.1 - 4.5e-05 22.8 0.0 0.00026 20.3 0.0 1.8 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_25 PF13481.1 AEO53945.1 - 0.0032 16.8 0.2 0.032 13.6 0.2 2.5 1 1 0 1 1 1 1 AAA domain DEAD PF00270.24 AEO53945.1 - 0.0061 16.0 0.0 0.077 12.4 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Flavi_DEAD PF07652.9 AEO53945.1 - 0.0067 16.1 0.0 0.024 14.3 0.0 2.0 2 0 0 2 2 2 1 Flavivirus DEAD domain AAA_16 PF13191.1 AEO53945.1 - 0.01 15.8 0.0 0.025 14.5 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain UvrD_C_2 PF13538.1 AEO53945.1 - 0.013 15.5 0.0 7 6.8 0.0 2.7 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain PhoH PF02562.11 AEO53945.1 - 0.015 14.5 0.0 0.13 11.5 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_10 PF12846.2 AEO53945.1 - 0.016 14.6 0.0 0.062 12.7 0.0 1.8 1 1 1 2 2 2 0 AAA-like domain T2SE PF00437.15 AEO53945.1 - 0.016 14.1 0.0 0.028 13.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein 4HB_MCP_1 PF12729.2 AEO53945.1 - 0.017 14.5 0.1 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction AAA PF00004.24 AEO53945.1 - 0.022 14.9 0.0 0.089 12.9 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 AEO53945.1 - 0.022 14.2 0.0 0.059 12.8 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_5 PF07728.9 AEO53945.1 - 0.036 13.7 0.0 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 AEO53945.1 - 0.046 13.1 0.0 0.13 11.6 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein Zot PF05707.7 AEO53945.1 - 0.046 13.1 0.0 0.18 11.2 0.0 2.0 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) UvrD_C PF13361.1 AEO53945.1 - 0.064 12.6 0.0 22 4.3 0.0 3.0 2 1 1 3 3 3 0 UvrD-like helicase C-terminal domain AAA_33 PF13671.1 AEO53945.1 - 0.091 12.6 0.0 0.44 10.4 0.0 2.2 2 1 0 2 2 1 0 AAA domain TrwB_AAD_bind PF10412.4 AEO53945.1 - 0.12 10.9 0.0 0.21 10.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_17 PF13207.1 AEO53945.1 - 0.28 11.9 3.6 0.69 10.7 0.3 3.1 3 1 0 3 3 3 0 AAA domain DUF202 PF02656.10 AEO53946.1 - 2.5e-25 88.4 2.2 2.5e-25 88.4 1.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Cytochrom_B_N PF00033.14 AEO53946.1 - 0.046 13.0 2.8 0.061 12.6 2.0 1.1 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB DUF3784 PF12650.2 AEO53946.1 - 0.09 12.7 1.5 0.15 11.9 1.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3784) Ni_hydr_CYTB PF01292.15 AEO53946.1 - 0.21 10.9 2.6 0.26 10.6 1.8 1.1 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 DUF2975 PF11188.3 AEO53946.1 - 0.47 10.1 3.4 0.87 9.3 2.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2975) Aldo_ket_red PF00248.16 AEO53948.1 - 2e-50 171.2 0.0 2.2e-50 171.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RHH_1 PF01402.16 AEO53948.1 - 1.3 9.0 6.6 1.2 9.1 0.9 3.2 4 0 0 4 4 4 0 Ribbon-helix-helix protein, copG family SHR3_chaperone PF08229.6 AEO53949.1 - 5.8e-65 217.9 2.0 2.7e-64 215.7 1.4 1.8 1 1 0 1 1 1 1 ER membrane protein SH3 DUF4131 PF13567.1 AEO53949.1 - 0.1 11.9 0.9 0.75 9.1 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) CD99L2 PF12301.3 AEO53950.1 - 0.0011 18.6 0.4 0.0027 17.4 0.3 1.6 1 0 0 1 1 1 1 CD99 antigen like protein 2 Haemadin PF09065.5 AEO53950.1 - 0.028 13.9 7.3 0.066 12.8 5.0 1.6 1 0 0 1 1 1 0 Haemadin DUF4366 PF14283.1 AEO53950.1 - 0.03 13.7 0.6 0.079 12.3 0.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Adipogenin PF15202.1 AEO53951.1 - 3.2 7.6 5.1 1 9.2 1.8 1.5 1 1 1 2 2 2 0 Adipogenin Fungal_trans_2 PF11951.3 AEO53952.1 - 3.7e-73 246.3 0.1 4.7e-73 245.9 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO53952.1 - 7.1e-08 32.2 5.9 1.2e-07 31.5 4.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SAM_2 PF07647.12 AEO53954.1 - 0.00012 21.8 0.0 0.00025 20.8 0.0 1.6 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 AEO53954.1 - 0.0046 17.1 0.0 0.0096 16.0 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.24 AEO53954.1 - 0.0058 16.8 0.0 0.04 14.1 0.0 2.3 1 1 0 1 1 1 1 PH domain SR-25 PF10500.4 AEO53954.1 - 0.14 11.6 18.0 0.034 13.6 7.3 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Sod_Fe_C PF02777.13 AEO53955.1 - 1.2e-10 41.1 0.0 0.00034 20.3 0.0 2.4 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Bd3614_N PF14442.1 AEO53956.1 - 3.1 7.7 7.3 1.4 8.8 2.8 2.1 2 0 0 2 2 2 0 Bd3614-like deaminase N-terminal Mito_carr PF00153.22 AEO53957.1 - 7.4e-65 214.7 2.3 1.1e-21 76.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein ApoO PF09769.4 AEO53958.1 - 2.3e-51 173.6 1.6 2.8e-51 173.3 0.0 2.0 3 0 0 3 3 3 1 Apolipoprotein O TspO_MBR PF03073.10 AEO53958.1 - 0.091 12.2 0.1 0.18 11.3 0.1 1.5 1 0 0 1 1 1 0 TspO/MBR family Peptidase_M3 PF01432.15 AEO53959.1 - 5.8e-118 394.8 0.0 9e-118 394.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 AEO53959.1 - 0.051 12.9 0.3 0.086 12.2 0.2 1.3 1 0 0 1 1 1 0 Peptidase M50B-like Ketoacyl-synt_2 PF13723.1 AEO53959.1 - 0.1 11.8 2.4 5 6.3 0.1 2.4 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain WSC PF01822.14 AEO53960.1 - 7.5e-16 57.8 6.0 1.2e-15 57.1 4.1 1.4 1 0 0 1 1 1 1 WSC domain IMS PF00817.15 AEO53961.1 - 8.3e-40 136.0 0.0 1.7e-39 135.0 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 AEO53961.1 - 1.7e-18 66.7 0.0 3.2e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 AEO53961.1 - 7.1e-15 54.8 0.5 7.6e-07 29.0 0.1 3.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4414) BRCT PF00533.21 AEO53961.1 - 0.013 15.6 0.0 0.033 14.3 0.0 1.7 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain HHH_5 PF14520.1 AEO53961.1 - 0.014 15.5 0.1 0.043 13.9 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain IMS_HHH PF11798.3 AEO53961.1 - 0.014 15.4 0.1 0.014 15.4 0.0 3.2 4 0 0 4 4 4 0 IMS family HHH motif PTCB-BRCT PF12738.2 AEO53961.1 - 0.024 14.4 0.1 0.099 12.5 0.0 2.2 2 0 0 2 2 2 0 twin BRCT domain DUF1805 PF08827.6 AEO53961.1 - 0.077 12.8 0.0 0.23 11.2 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) RED_N PF07808.8 AEO53962.1 - 1.2e-09 37.7 9.8 1.2e-09 37.7 6.8 3.2 4 0 0 4 4 4 1 RED-like protein N-terminal region IU_nuc_hydro PF01156.14 AEO53963.1 - 7.2e-36 123.9 0.0 8e-36 123.8 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Pkinase PF00069.20 AEO53964.1 - 3.1e-35 121.5 0.0 2.2e-21 76.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AEO53964.1 - 3.2e-13 49.3 0.0 5.5e-10 38.7 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 AEO53964.1 - 9.2e-05 22.2 0.0 0.00029 20.6 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 AEO53964.1 - 0.004 16.1 0.0 2.3 7.1 0.0 2.2 2 0 0 2 2 2 2 Kinase-like CAP_GLY PF01302.20 AEO53965.1 - 6e-17 61.1 0.5 1.6e-16 59.7 0.2 1.8 2 0 0 2 2 1 1 CAP-Gly domain Med4 PF10018.4 AEO53965.1 - 1.4e-06 27.8 13.3 0.0021 17.4 0.6 3.8 3 0 0 3 3 3 2 Vitamin-D-receptor interacting Mediator subunit 4 Phage_GP20 PF06810.6 AEO53965.1 - 0.0005 19.5 9.3 0.047 13.1 1.1 2.9 3 0 0 3 3 3 2 Phage minor structural protein GP20 AAA_13 PF13166.1 AEO53965.1 - 0.0012 17.4 5.9 0.0012 17.4 4.1 2.7 1 1 1 3 3 3 1 AAA domain NPV_P10 PF05531.7 AEO53965.1 - 0.0035 17.5 6.1 0.22 11.7 0.7 3.1 3 0 0 3 3 2 1 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.4 AEO53965.1 - 0.013 15.6 1.8 0.013 15.6 1.2 3.2 4 0 0 4 4 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Reo_sigmaC PF04582.7 AEO53965.1 - 0.15 11.2 6.2 3.3 6.7 0.3 3.0 1 1 1 3 3 3 0 Reovirus sigma C capsid protein TMF_DNA_bd PF12329.3 AEO53965.1 - 0.25 11.1 39.0 0.17 11.7 1.3 5.7 3 1 1 5 5 5 0 TATA element modulatory factor 1 DNA binding TPR_MLP1_2 PF07926.7 AEO53965.1 - 0.26 11.0 26.8 0.041 13.6 7.3 3.6 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Baculo_PEP_C PF04513.7 AEO53965.1 - 0.33 10.7 4.1 0.7 9.7 0.8 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.6 AEO53965.1 - 0.47 9.0 25.0 0.4 9.2 1.4 3.1 1 1 1 3 3 3 0 Spc7 kinetochore protein WEMBL PF05701.6 AEO53965.1 - 0.64 8.4 32.0 2.6 6.4 22.2 2.1 1 1 0 1 1 1 0 Weak chloroplast movement under blue light ISG65-75 PF11727.3 AEO53965.1 - 0.84 8.6 11.1 0.56 9.2 2.3 2.4 1 1 1 2 2 2 0 Invariant surface glycoprotein IncA PF04156.9 AEO53965.1 - 1 8.8 32.4 39 3.7 0.0 3.6 2 1 0 2 2 1 0 IncA protein Fib_alpha PF08702.5 AEO53965.1 - 1.1 9.3 9.9 14 5.7 0.0 3.4 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF812 PF05667.6 AEO53965.1 - 1.1 7.6 23.4 0.28 9.6 9.9 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF812) Mod_r PF07200.8 AEO53965.1 - 1.2 8.9 14.4 0.16 11.8 1.9 3.0 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Lectin_N PF03954.9 AEO53965.1 - 1.4 8.3 3.8 2.6 7.4 0.0 2.7 3 0 0 3 3 2 0 Hepatic lectin, N-terminal domain FUSC PF04632.7 AEO53965.1 - 1.8 6.8 19.2 0.23 9.8 10.3 1.7 2 0 0 2 2 2 0 Fusaric acid resistance protein family Pkip-1 PF06878.6 AEO53965.1 - 1.9 8.3 7.5 5.3 6.9 0.4 2.5 1 1 1 2 2 2 0 Pkip-1 protein Seryl_tRNA_N PF02403.17 AEO53965.1 - 2.1 8.3 23.4 1.2 9.1 3.7 4.4 4 0 0 4 4 4 0 Seryl-tRNA synthetase N-terminal domain CENP-F_leu_zip PF10473.4 AEO53965.1 - 2.2 8.1 36.3 2.5 7.9 5.5 4.1 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cauli_AT PF03233.8 AEO53965.1 - 2.8 7.6 4.1 1.4 8.6 0.7 2.0 2 0 0 2 2 2 0 Aphid transmission protein Glutaredoxin2_C PF04399.8 AEO53965.1 - 2.9 7.4 9.7 6 6.4 0.1 3.1 3 0 0 3 3 3 0 Glutaredoxin 2, C terminal domain PilJ PF13675.1 AEO53965.1 - 3.3 8.0 19.1 0.35 11.1 3.3 3.9 1 1 3 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term TBPIP PF07106.8 AEO53965.1 - 4 6.9 21.9 5.3 6.5 4.0 3.6 2 1 2 4 4 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF16 PF01519.11 AEO53965.1 - 4 7.7 7.6 29 4.9 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function DUF16 EMP24_GP25L PF01105.19 AEO53965.1 - 4.1 7.0 4.7 0.98 9.1 0.5 2.0 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD ADIP PF11559.3 AEO53965.1 - 5.5 6.8 26.2 2.2 8.1 0.6 3.7 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding Fez1 PF06818.10 AEO53965.1 - 6.7 6.6 37.3 0.11 12.4 11.2 3.5 2 2 0 3 3 3 0 Fez1 FlxA PF14282.1 AEO53965.1 - 8.2 6.4 10.7 16 5.4 3.0 3.5 3 1 0 3 3 2 0 FlxA-like protein HEAT_2 PF13646.1 AEO53966.1 - 0.035 14.3 2.3 0.076 13.3 0.1 2.6 3 1 0 3 3 3 0 HEAT repeats Nop14 PF04147.7 AEO53967.1 - 1.8e-267 889.6 24.5 2.1e-267 889.3 17.0 1.0 1 0 0 1 1 1 1 Nop14-like family Glyco_hydro_38 PF01074.17 AEO53968.1 - 2.5e-91 305.7 0.1 4.8e-91 304.8 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 AEO53968.1 - 5.8e-77 259.4 0.0 9.9e-77 258.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 AEO53968.1 - 1.7e-25 89.0 0.0 4.2e-25 87.7 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Daxx PF03344.10 AEO53969.1 - 0.062 11.7 20.0 0.097 11.1 13.9 1.2 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 AEO53969.1 - 1.5 6.6 24.1 2 6.2 16.7 1.1 1 0 0 1 1 1 0 Nop14-like family DUF1510 PF07423.6 AEO53969.1 - 2.1 7.6 14.3 4.2 6.6 9.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) MutS_V PF00488.16 AEO53970.1 - 1.7e-76 256.6 0.0 3e-76 255.9 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 AEO53970.1 - 2.6e-39 135.1 5.9 4.8e-39 134.2 4.1 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 AEO53970.1 - 1.8e-19 69.8 0.0 1.2e-18 67.2 0.0 2.2 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.12 AEO53970.1 - 2.2e-05 24.5 0.0 6.3e-05 23.0 0.0 1.8 1 1 0 1 1 1 1 MutS domain II AAA_22 PF13401.1 AEO53970.1 - 0.0045 17.1 0.0 0.35 11.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain MutS_IV PF05190.13 AEO53970.1 - 0.0068 16.5 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 MutS family domain IV AAA_29 PF13555.1 AEO53970.1 - 0.016 14.6 0.0 0.045 13.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.2 AEO53970.1 - 0.062 12.7 1.2 14 4.9 0.0 3.3 2 2 1 3 3 3 0 AAA-like domain AAA_14 PF13173.1 AEO53970.1 - 0.2 11.5 0.0 0.8 9.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 AEO53970.1 - 0.27 11.5 0.1 1.1 9.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain Ribosomal_L10 PF00466.15 AEO53971.1 - 6.3e-25 87.0 0.0 1.6e-24 85.7 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 AEO53971.1 - 6.6e-15 55.2 4.9 6.6e-15 55.2 3.4 2.3 2 0 0 2 2 2 1 60s Acidic ribosomal protein VirE_N PF08800.5 AEO53971.1 - 0.11 12.2 0.0 0.38 10.5 0.0 1.8 2 0 0 2 2 2 0 VirE N-terminal domain DUF2191 PF09957.4 AEO53971.1 - 0.13 12.0 0.1 0.13 12.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2191) WD40 PF00400.27 AEO53972.1 - 2.1e-06 27.3 0.6 0.0018 18.0 0.0 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat DnaJ PF00226.26 AEO53973.1 - 1.2e-26 92.1 1.4 2.2e-26 91.3 1.0 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 AEO53973.1 - 5.8e-21 74.1 0.1 3e-18 65.4 0.0 2.7 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 AEO53973.1 - 9.7e-14 51.1 17.0 2e-13 50.1 11.8 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 AEO53973.1 - 0.071 12.8 9.1 0.25 11.0 1.2 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family zinc-ribbons_6 PF07191.7 AEO53973.1 - 0.16 11.8 5.2 5.2 6.9 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbons zf-RING_3 PF14369.1 AEO53973.1 - 0.22 11.5 1.9 25 4.9 0.0 2.9 3 0 0 3 3 3 0 zinc-finger DUF2614 PF11023.3 AEO53973.1 - 1.4 8.7 5.3 12 5.7 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2614) Lar_restr_allev PF14354.1 AEO53973.1 - 1.5 9.1 5.1 6.9 7.0 3.6 2.1 1 1 0 1 1 1 0 Restriction alleviation protein Lar zf-HC5HC2H_2 PF13832.1 AEO53974.1 - 3.3e-19 68.8 0.6 3.3e-19 68.8 0.4 4.3 5 0 0 5 5 5 2 PHD-zinc-finger like domain BAH PF01426.13 AEO53974.1 - 2.1e-17 62.9 0.1 4.9e-17 61.7 0.0 1.7 1 0 0 1 1 1 1 BAH domain zf-HC5HC2H PF13771.1 AEO53974.1 - 8.9e-16 57.8 2.1 8.9e-16 57.8 1.4 4.9 5 0 0 5 5 5 1 PHD-like zinc-binding domain PHD PF00628.24 AEO53974.1 - 1.5e-10 40.5 60.3 6.1e-06 25.8 4.2 6.7 7 0 0 7 7 7 3 PHD-finger PHD_2 PF13831.1 AEO53974.1 - 5.2e-08 32.0 2.9 5.2e-08 32.0 2.0 5.4 6 0 0 6 6 6 2 PHD-finger Myb_DNA-binding PF00249.26 AEO53974.1 - 0.0012 18.8 0.7 0.0035 17.3 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain C1_1 PF00130.17 AEO53974.1 - 0.0047 16.6 1.7 0.0047 16.6 1.2 5.5 5 1 1 6 6 6 3 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 AEO53974.1 - 0.1 12.3 48.0 0.032 13.9 1.2 4.9 6 0 0 6 6 6 0 Prokaryotic RING finger family 1 TrkA_C PF02080.16 AEO53974.1 - 0.46 10.0 0.0 0.95 9.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-C domain DEAD PF00270.24 AEO53975.1 - 3.7e-20 72.0 0.0 3.9e-19 68.7 0.0 2.3 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO53975.1 - 1.5e-08 34.4 0.0 3.1e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AEO53975.1 - 0.0001 22.2 0.0 0.00029 20.7 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit HHH_5 PF14520.1 AEO53975.1 - 0.00015 21.8 0.1 0.00055 20.0 0.1 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix domain Abhydrolase_6 PF12697.2 AEO53977.1 - 1.4e-17 64.3 0.8 1.6e-16 60.8 0.6 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO53977.1 - 7.7e-11 41.9 0.0 3.9e-10 39.6 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AEO53977.1 - 6.3e-09 35.7 0.0 1.7e-06 27.8 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Esterase PF00756.15 AEO53977.1 - 0.0037 16.7 0.0 0.0061 16.0 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Peptidase_S28 PF05577.7 AEO53977.1 - 0.0087 14.6 0.0 0.012 14.1 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Bcl-2_BAD PF10514.4 AEO53977.1 - 0.098 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Pro-apoptotic Bcl-2 protein, BAD TMF_DNA_bd PF12329.3 AEO53978.1 - 0.14 12.0 0.6 1.6 8.5 0.0 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding SNARE_assoc PF09335.6 AEO53979.1 - 5.7e-13 49.1 6.5 5.7e-13 49.1 4.5 2.7 2 1 0 3 3 3 1 SNARE associated Golgi protein HAMP PF00672.20 AEO53979.1 - 0.47 10.6 8.7 0.56 10.4 0.0 3.4 3 0 0 3 3 3 0 HAMP domain DUF1771 PF08590.5 AEO53980.1 - 1.4e-13 50.6 10.4 3.8e-13 49.2 7.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 AEO53980.1 - 5.8e-10 39.2 0.0 3.7e-09 36.6 0.0 2.4 2 0 0 2 2 2 1 Smr domain zf-CCCH PF00642.19 AEO53980.1 - 1.2e-06 28.0 1.7 0.0034 17.0 0.2 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HBS1_N PF08938.5 AEO53980.1 - 0.0094 16.0 0.8 0.096 12.8 0.0 2.3 2 0 0 2 2 2 1 HBS1 N-terminus Cupin_8 PF13621.1 AEO53981.1 - 2.5e-18 66.4 0.0 1.5e-17 63.9 0.0 1.9 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 AEO53981.1 - 5.1e-10 39.5 0.0 2e-09 37.7 0.0 2.0 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.2 AEO53981.1 - 6.9e-06 25.6 0.0 1.7e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 AEO53981.1 - 0.027 14.1 0.0 0.069 12.8 0.0 1.7 1 0 0 1 1 1 0 F-box domain Cupin_4 PF08007.7 AEO53981.1 - 0.14 11.4 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 Cupin superfamily protein DEAD PF00270.24 AEO53982.1 - 2.4e-42 144.2 0.8 4.9e-42 143.2 0.4 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO53982.1 - 4.3e-28 96.9 0.1 4.9e-27 93.6 0.1 2.5 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 AEO53982.1 - 0.0013 18.5 0.0 0.0029 17.4 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 AEO53982.1 - 0.012 14.7 0.3 0.027 13.5 0.0 1.6 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.1 AEO53982.1 - 0.018 15.1 0.2 0.066 13.3 0.1 2.0 1 1 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.9 AEO53982.1 - 0.023 14.4 0.1 0.21 11.3 0.1 2.3 1 1 0 1 1 1 0 Flavivirus DEAD domain AAA_19 PF13245.1 AEO53982.1 - 0.028 14.1 0.1 0.11 12.3 0.1 1.9 1 1 0 1 1 1 0 Part of AAA domain tRNA-synt_1b PF00579.20 AEO53982.1 - 0.039 13.0 0.0 0.24 10.5 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) CobA_CobO_BtuR PF02572.10 AEO53982.1 - 0.054 13.1 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Fanconi_A PF03511.9 AEO53982.1 - 0.086 12.6 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 Fanconi anaemia group A protein RRM_1 PF00076.17 AEO53983.1 - 3.4e-18 65.0 0.0 1.5e-17 62.9 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO53983.1 - 7.7e-13 48.2 0.0 1.3e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO53983.1 - 1.5e-05 24.6 0.0 2.9e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Daxx PF03344.10 AEO53984.1 - 0.0053 15.3 33.4 0.0071 14.9 23.2 1.2 1 0 0 1 1 1 1 Daxx Family DUF572 PF04502.8 AEO53984.1 - 0.52 9.4 37.4 0.72 9.0 25.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) VID27 PF08553.5 AEO53984.1 - 6.7 4.8 27.9 12 3.9 19.3 1.3 1 0 0 1 1 1 0 VID27 cytoplasmic protein F-box-like PF12937.2 AEO53985.1 - 3e-05 23.6 0.0 6.6e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 F-box-like DUF2415 PF10313.4 AEO53985.1 - 0.1 12.2 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) AP_endonuc_2 PF01261.19 AEO53986.1 - 3e-31 108.3 0.3 4.5e-31 107.7 0.2 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Pkinase PF00069.20 AEO53987.1 - 2.7e-10 39.8 0.0 1.6e-09 37.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO53987.1 - 0.014 14.5 0.0 0.056 12.5 0.0 1.8 2 0 0 2 2 2 0 Protein tyrosine kinase Enolase_C PF00113.17 AEO53988.1 - 5.3e-155 514.7 0.0 6.7e-155 514.4 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 AEO53988.1 - 1.1e-57 193.6 0.1 2.2e-57 192.6 0.0 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE PF01188.16 AEO53988.1 - 0.0097 16.4 0.0 0.022 15.2 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MAAL_C PF07476.6 AEO53988.1 - 0.011 14.6 0.1 0.15 10.9 0.1 2.3 3 0 0 3 3 3 0 Methylaspartate ammonia-lyase C-terminus MR_MLE_C PF13378.1 AEO53988.1 - 0.033 14.1 0.0 0.079 12.9 0.0 1.6 1 0 0 1 1 1 0 Enolase C-terminal domain-like Peptidase_M1 PF01433.15 AEO53989.1 - 2.9e-142 474.3 0.0 4.6e-142 473.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 AEO53989.1 - 1.2e-95 320.4 0.0 2e-95 319.7 0.0 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 AEO53989.1 - 1.9e-20 73.1 0.2 4.4e-20 72.0 0.2 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily DUF4110 PF13422.1 AEO53990.1 - 1.1e-28 98.8 0.4 1.1e-28 98.8 0.3 3.8 4 1 0 4 4 4 1 Domain of unknown function (DUF4110) Kelch_3 PF13415.1 AEO53990.1 - 3.5e-26 90.7 17.8 6.6e-10 38.8 0.1 6.8 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_4 PF13418.1 AEO53990.1 - 3.2e-20 71.6 17.8 3.6e-05 23.4 0.3 6.2 5 2 1 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 AEO53990.1 - 9.6e-19 66.9 4.5 2.7e-07 30.3 0.0 6.2 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.1 AEO53990.1 - 1.2e-14 53.7 2.2 6.5e-05 22.9 0.1 5.5 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.20 AEO53990.1 - 1.3e-14 53.4 0.5 9.6e-06 25.0 0.0 5.5 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.10 AEO53990.1 - 7.4e-14 50.8 6.2 0.015 15.0 0.0 6.0 6 1 0 6 6 6 4 Kelch motif WLM PF08325.5 AEO53991.1 - 2.6e-41 141.5 4.1 4.9e-41 140.6 1.6 2.3 2 1 0 2 2 2 1 WLM domain DUF45 PF01863.12 AEO53991.1 - 5.2e-08 32.9 2.1 5.9e-08 32.7 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function DUF45 Ribosomal_60s PF00428.14 AEO53991.1 - 0.23 11.8 5.9 0.66 10.4 4.1 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF3090 PF11290.3 AEO53992.1 - 0.14 11.6 0.1 0.3 10.5 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3090) zf-HIT PF04438.11 AEO53993.1 - 1.2e-09 37.6 4.5 1.7e-09 37.1 3.1 1.3 1 0 0 1 1 1 1 HIT zinc finger IncA PF04156.9 AEO53994.1 - 0.043 13.4 0.0 0.056 13.0 0.0 1.2 1 0 0 1 1 1 0 IncA protein TMF_DNA_bd PF12329.3 AEO53994.1 - 0.22 11.3 1.8 0.29 10.9 1.3 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Thioredoxin PF00085.15 AEO53995.1 - 5.3e-61 202.7 11.0 1.5e-31 108.1 0.2 4.3 4 1 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 AEO53995.1 - 1.3e-54 184.7 6.3 8.4e-39 133.2 1.3 3.3 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 AEO53995.1 - 1.8e-13 50.3 0.1 8.4e-05 22.6 0.0 3.8 3 0 0 3 3 3 3 Thioredoxin-like Thioredoxin_7 PF13899.1 AEO53995.1 - 8.5e-12 44.9 0.5 0.00014 21.7 0.0 3.7 4 0 0 4 4 4 2 Thioredoxin-like Thioredoxin_2 PF13098.1 AEO53995.1 - 2.5e-11 43.7 6.5 0.00018 21.6 0.1 4.7 3 2 1 4 4 4 2 Thioredoxin-like domain AhpC-TSA PF00578.16 AEO53995.1 - 5.9e-10 38.8 3.1 0.0016 18.1 0.1 3.6 3 0 0 3 3 3 3 AhpC/TSA family Redoxin PF08534.5 AEO53995.1 - 1.4e-09 37.6 7.5 0.00083 18.9 0.0 3.6 4 0 0 4 4 4 3 Redoxin Calsequestrin PF01216.12 AEO53995.1 - 7.6e-08 31.5 3.6 1.3e-07 30.7 2.5 1.3 1 0 0 1 1 1 1 Calsequestrin ERp29_N PF07912.8 AEO53995.1 - 1.8e-06 27.9 1.7 0.79 9.6 0.0 4.2 3 1 0 3 3 3 2 ERp29, N-terminal domain Thioredoxin_4 PF13462.1 AEO53995.1 - 0.0085 16.1 5.9 1.2 9.1 0.0 3.9 3 2 0 3 3 3 2 Thioredoxin DSBA PF01323.15 AEO53995.1 - 0.062 12.8 0.4 6.1 6.3 0.1 3.3 3 1 0 3 3 3 0 DSBA-like thioredoxin domain Mon1 PF03164.9 AEO53996.1 - 3.2e-110 368.5 0.0 1.1e-72 244.8 0.0 2.6 2 1 0 2 2 2 2 Trafficking protein Mon1 Dopey_N PF04118.9 AEO53997.1 - 1.4e-100 336.0 0.0 3.8e-100 334.6 0.0 1.7 1 0 0 1 1 1 1 Dopey, N-terminal Methyltransf_15 PF09445.5 AEO53998.1 - 4.5e-42 143.3 0.0 1.5e-41 141.7 0.0 1.7 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.11 AEO53998.1 - 1.9e-05 24.3 0.0 2.1e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 AEO53998.1 - 2.7e-05 24.1 0.0 5.4e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO53998.1 - 5.7e-05 23.6 0.5 8.8e-05 23.0 0.3 1.6 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 AEO53998.1 - 0.0032 16.8 0.0 0.0063 15.9 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 UPF0020 PF01170.13 AEO53998.1 - 0.0037 16.8 0.1 0.021 14.4 0.0 2.0 2 1 0 2 2 2 1 Putative RNA methylase family UPF0020 Cnd2 PF05786.9 AEO53998.1 - 0.034 12.6 1.7 0.047 12.2 1.2 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 MTS PF05175.9 AEO53998.1 - 0.049 13.0 0.0 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DOT1 PF08123.8 AEO53998.1 - 0.05 12.8 0.0 0.078 12.2 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_31 PF13847.1 AEO53998.1 - 0.077 12.5 0.0 0.25 10.9 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain SPT6_acidic PF14632.1 AEO53998.1 - 0.091 12.9 7.1 0.16 12.1 4.9 1.3 1 0 0 1 1 1 0 Acidic N-terminal SPT6 DNA_methylase PF00145.12 AEO53998.1 - 0.11 11.5 0.6 0.2 10.7 0.0 1.6 1 1 1 2 2 2 0 C-5 cytosine-specific DNA methylase GRASP55_65 PF04495.9 AEO53999.1 - 9.8e-49 164.9 0.0 2.2e-47 160.5 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain GRP PF07172.6 AEO54001.1 - 3.4e-06 27.4 10.8 5.9e-06 26.6 7.5 1.4 1 0 0 1 1 1 1 Glycine rich protein family DUF202 PF02656.10 AEO54001.1 - 0.00063 19.9 1.8 0.0026 17.9 0.7 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF1183 PF06682.7 AEO54001.1 - 0.092 12.3 0.4 0.11 12.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Zn_clus PF00172.13 AEO54002.1 - 2.6e-07 30.4 7.4 3.8e-07 29.8 5.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank PF00023.25 AEO54003.1 - 5.1e-22 76.5 3.8 4e-05 23.2 0.2 6.3 6 0 0 6 6 6 5 Ankyrin repeat Ank_2 PF12796.2 AEO54003.1 - 2.7e-20 72.4 0.4 7.5e-06 26.2 0.0 5.3 3 3 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 AEO54003.1 - 5.5e-18 63.2 0.0 0.0026 17.8 0.0 6.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 AEO54003.1 - 5.6e-14 51.8 4.8 0.023 14.9 0.1 5.9 5 0 0 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 AEO54003.1 - 1.1e-09 38.4 3.4 1.8 9.1 0.0 5.9 6 0 0 6 6 6 4 Ankyrin repeats (many copies) CRCB PF02537.10 AEO54003.1 - 0.22 11.4 0.0 0.35 10.7 0.0 1.3 1 0 0 1 1 1 0 CrcB-like protein AA_permease_2 PF13520.1 AEO54004.1 - 0.0037 15.8 0.1 0.0044 15.6 0.1 1.0 1 0 0 1 1 1 1 Amino acid permease Yip1 PF04893.12 AEO54004.1 - 0.015 14.7 0.4 0.017 14.6 0.3 1.1 1 0 0 1 1 1 0 Yip1 domain DUF1282 PF06930.7 AEO54004.1 - 0.021 14.4 0.1 0.022 14.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) MFS_1 PF07690.11 AEO54004.1 - 0.04 12.6 0.9 0.047 12.4 0.7 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily Tetraspannin PF00335.15 AEO54004.1 - 0.11 11.7 0.6 0.13 11.5 0.4 1.1 1 0 0 1 1 1 0 Tetraspanin family TMEMspv1-c74-12 PF11044.3 AEO54004.1 - 5.6 6.5 6.2 6.4 6.4 0.2 2.2 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Sod_Cu PF00080.15 AEO54005.1 - 1.9e-15 57.2 0.1 2.8e-15 56.6 0.1 1.4 1 1 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Nucleoplasmin PF03066.10 AEO54005.1 - 0.075 12.5 1.3 0.11 11.9 0.9 1.3 1 0 0 1 1 1 0 Nucleoplasmin PAS_9 PF13426.1 AEO54005.1 - 0.085 13.2 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 PAS domain TFIIA PF03153.8 AEO54005.1 - 0.14 12.0 6.3 0.17 11.7 4.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NOA36 PF06524.7 AEO54005.1 - 0.14 11.3 5.4 0.17 11.0 3.7 1.1 1 0 0 1 1 1 0 NOA36 protein Sporozoite_P67 PF05642.6 AEO54005.1 - 0.17 9.6 4.0 0.24 9.2 2.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2457 PF10446.4 AEO54005.1 - 0.6 8.7 18.0 0.82 8.3 12.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) ATG27 PF09451.5 AEO54005.1 - 2.9 7.0 4.6 4.7 6.3 3.2 1.3 1 0 0 1 1 1 0 Autophagy-related protein 27 CDC45 PF02724.9 AEO54005.1 - 3.4 5.5 4.2 4.4 5.2 2.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 AEO54005.1 - 3.5 5.4 6.7 4.3 5.1 4.7 1.0 1 0 0 1 1 1 0 Nop14-like family Aminotran_5 PF00266.14 AEO54006.1 - 1.3e-12 47.2 0.0 1e-05 24.5 0.0 3.3 4 1 0 4 4 4 2 Aminotransferase class-V KAR9 PF08580.5 AEO54007.1 - 1.3e-139 466.5 5.7 1.3e-139 466.5 4.0 1.5 2 0 0 2 2 2 1 Yeast cortical protein KAR9 DNA_photolyase PF00875.13 AEO54007.1 - 0.081 12.6 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 DNA photolyase Syntaxin-6_N PF09177.6 AEO54007.1 - 0.27 11.6 14.1 0.59 10.5 0.8 4.5 2 2 1 4 4 4 0 Syntaxin 6, N-terminal DUF3829 PF12889.2 AEO54007.1 - 0.66 9.1 5.1 4.4 6.4 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3829) Prefoldin_2 PF01920.15 AEO54007.1 - 9.6 6.0 6.4 3.6 7.4 0.2 3.1 3 0 0 3 3 3 0 Prefoldin subunit Helicase_C PF00271.26 AEO54009.1 - 6.2e-22 77.2 0.0 1.6e-19 69.5 0.0 3.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 AEO54009.1 - 8.3e-19 67.6 0.0 2e-18 66.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase RQC PF09382.5 AEO54009.1 - 2.5e-07 30.3 0.1 6.2e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 RQC domain HRDC PF00570.18 AEO54009.1 - 0.0013 18.4 0.0 0.0047 16.6 0.0 2.0 1 0 0 1 1 1 1 HRDC domain DUF1275 PF06912.6 AEO54010.1 - 1.5e-43 148.4 17.9 2e-43 148.0 12.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) YrhC PF14143.1 AEO54010.1 - 0.23 11.4 1.4 2.3 8.2 0.2 2.4 2 0 0 2 2 2 0 YrhC-like protein DUF4118 PF13493.1 AEO54010.1 - 2 8.6 8.9 0.23 11.6 0.5 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4118) MFS_1 PF07690.11 AEO54011.1 - 7.9e-23 80.7 21.1 3.5e-22 78.6 14.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily zf-MYND PF01753.13 AEO54012.1 - 1.3e-09 37.8 12.8 2.1e-09 37.1 8.8 1.4 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.11 AEO54012.1 - 3.4 7.3 10.5 6.4 6.5 7.3 1.4 1 0 0 1 1 1 0 HIT zinc finger Brix PF04427.13 AEO54013.1 - 2.1e-37 128.6 0.0 2.8e-37 128.2 0.0 1.2 1 0 0 1 1 1 1 Brix domain Fungal_trans_2 PF11951.3 AEO54014.1 - 3.2e-05 22.7 0.4 5.9e-05 21.8 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Mito_fiss_reg PF05308.6 AEO54014.1 - 3.1 7.1 6.3 2.7 7.2 2.8 1.9 2 0 0 2 2 2 0 Mitochondrial fission regulator Cys_Met_Meta_PP PF01053.15 AEO54015.1 - 1.9e-139 464.2 0.2 2.2e-139 464.0 0.1 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 AEO54015.1 - 1.3e-07 30.7 1.1 4.8e-07 28.8 0.3 1.9 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 AEO54015.1 - 3.8e-07 29.4 0.3 7.1e-07 28.5 0.2 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 AEO54015.1 - 6.6e-07 28.6 0.1 1.1e-06 27.9 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 AEO54015.1 - 0.00027 20.1 1.0 0.00066 18.9 0.7 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.11 AEO54015.1 - 0.0033 16.1 0.2 0.0033 16.1 0.1 1.5 2 0 0 2 2 2 1 Glycine cleavage system P-protein DUF1765 PF08578.5 AEO54016.1 - 9.9e-48 161.3 0.1 1.6e-47 160.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) SBF PF01758.11 AEO54017.1 - 2.8e-45 154.0 10.7 2.8e-45 154.0 7.4 2.5 2 1 1 3 3 3 2 Sodium Bile acid symporter family Peptidase_C12 PF01088.16 AEO54018.1 - 1.3e-38 132.3 0.0 2.3e-38 131.5 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 dsrm PF00035.20 AEO54018.1 - 0.018 15.6 0.0 0.047 14.2 0.0 1.6 2 0 0 2 2 2 0 Double-stranded RNA binding motif CMV_1a PF12467.3 AEO54019.1 - 0.16 12.3 0.6 0.17 12.2 0.4 1.1 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family KH_1 PF00013.24 AEO54020.1 - 1.3e-40 136.8 7.5 1.3e-16 59.9 0.6 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 AEO54020.1 - 4.3e-31 106.0 13.4 2.6e-11 42.8 2.8 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 AEO54020.1 - 7.5e-13 47.8 5.4 0.0028 17.1 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 AEO54020.1 - 0.00019 20.9 2.5 0.95 9.1 0.1 3.3 3 0 0 3 3 3 2 KH domain KH_5 PF13184.1 AEO54020.1 - 0.0025 17.5 7.2 0.79 9.5 0.1 3.4 3 0 0 3 3 3 2 NusA-like KH domain CENP-K PF11802.3 AEO54021.1 - 1.3e-10 40.9 2.2 2.9e-06 26.7 0.0 2.1 2 0 0 2 2 2 2 Centromere-associated protein K IncA PF04156.9 AEO54021.1 - 0.00013 21.6 6.9 0.00013 21.6 4.8 1.6 2 0 0 2 2 2 1 IncA protein AMH_N PF04709.7 AEO54021.1 - 0.00058 18.9 3.6 0.0038 16.2 3.0 1.8 1 1 1 2 2 2 1 Anti-Mullerian hormone, N terminal region Atg14 PF10186.4 AEO54021.1 - 0.0011 18.0 4.1 0.0011 18.0 2.8 1.7 2 0 0 2 2 2 1 UV radiation resistance protein and autophagy-related subunit 14 CENP-Q PF13094.1 AEO54021.1 - 0.15 12.1 16.1 0.21 11.6 8.0 2.2 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Exonuc_VII_L PF02601.10 AEO54021.1 - 0.17 11.0 5.3 0.23 10.6 3.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.14 AEO54021.1 - 0.31 8.8 4.4 0.43 8.3 3.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family BTV_NS2 PF04514.7 AEO54021.1 - 1.4 7.6 10.8 1 8.1 2.5 2.0 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 HAUS6_N PF14661.1 AEO54021.1 - 2.2 7.5 10.5 0.23 10.7 4.1 1.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus CDC37_N PF03234.9 AEO54021.1 - 2.4 8.4 11.2 6.9 6.9 5.5 2.1 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding FUSC PF04632.7 AEO54021.1 - 2.6 6.3 14.0 0.85 7.9 3.6 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein family Flu_NS2 PF00601.14 AEO54021.1 - 5 7.4 6.6 18 5.6 1.2 3.2 2 1 1 3 3 3 0 Influenza non-structural protein (NS2) HSP70 PF00012.15 AEO54021.1 - 7.1 4.4 11.1 8 4.2 5.7 1.9 2 0 0 2 2 2 0 Hsp70 protein dUTPase PF00692.14 AEO54022.1 - 1.1e-41 141.3 0.0 1.3e-41 141.0 0.0 1.1 1 0 0 1 1 1 1 dUTPase Phos_pyr_kin PF08543.7 AEO54023.1 - 1.9e-10 40.3 0.0 5.6e-10 38.8 0.0 1.7 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 AEO54023.1 - 1.9e-08 33.8 2.9 1.1e-05 24.7 0.0 2.7 2 1 0 3 3 3 2 pfkB family carbohydrate kinase PCNA_N PF00705.13 AEO54024.1 - 4.3e-56 187.8 4.7 8.1e-56 186.9 2.5 1.8 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 AEO54024.1 - 4.6e-51 172.0 0.1 1.6e-50 170.3 0.0 1.8 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 AEO54024.1 - 2.3e-09 36.7 0.1 2.7e-09 36.5 0.1 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.11 AEO54024.1 - 5.8e-07 28.5 1.5 3.6e-05 22.6 1.1 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.7 AEO54024.1 - 0.00015 20.8 0.1 0.0062 15.5 0.0 2.1 2 0 0 2 2 2 1 Hus1-like protein DNA_pol3_beta_3 PF02768.10 AEO54024.1 - 0.012 15.1 0.4 0.29 10.7 0.1 2.6 2 2 0 2 2 2 0 DNA polymerase III beta subunit, C-terminal domain IL12p40_C PF10420.4 AEO54024.1 - 0.054 13.5 0.1 0.23 11.5 0.0 2.0 2 0 0 2 2 2 0 Cytokine interleukin-12p40 C-terminus Vezatin PF12632.2 AEO54025.1 - 2.8e-61 206.8 0.1 5.2e-61 205.9 0.1 1.4 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes DUF3995 PF13160.1 AEO54025.1 - 0.0067 16.4 1.9 0.018 15.1 1.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3995) TPR_MLP1_2 PF07926.7 AEO54025.1 - 6.4 6.5 8.6 0.11 12.1 0.5 2.2 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Rab5ip PF07019.7 AEO54026.1 - 3.8e-26 91.0 3.2 4.6e-26 90.7 2.2 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) GTP_EFTU PF00009.22 AEO54027.1 - 3.4e-10 39.6 0.0 8.5e-10 38.3 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 AEO54027.1 - 0.018 14.5 0.7 3.8 6.9 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.1 AEO54027.1 - 0.057 12.9 0.4 0.12 11.9 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 AEO54027.1 - 0.072 13.0 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase T2SE PF00437.15 AEO54027.1 - 0.22 10.3 0.4 0.39 9.5 0.3 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Cas_Cas4 PF01930.12 AEO54028.1 - 0.8 9.5 7.2 1.7 8.5 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function DUF83 HA2 PF04408.18 AEO54029.1 - 5.8e-18 64.7 0.0 1.1e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 AEO54029.1 - 1.5e-15 57.0 0.0 4.2e-15 55.5 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 AEO54029.1 - 1.2e-14 53.9 0.0 8.3e-14 51.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 AEO54029.1 - 1.1e-06 28.3 0.0 8e-06 25.4 0.0 2.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 AEO54029.1 - 6.3e-05 23.1 0.0 0.00017 21.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 AEO54029.1 - 0.0079 15.6 0.1 0.029 13.9 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.22 AEO54029.1 - 0.016 15.5 0.0 0.047 13.9 0.0 1.8 1 0 0 1 1 1 0 ABC transporter DUF258 PF03193.11 AEO54029.1 - 0.072 12.2 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 T2SE PF00437.15 AEO54029.1 - 0.09 11.6 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.1 AEO54029.1 - 0.13 12.2 0.4 2.4 8.1 0.0 2.9 4 0 0 4 4 4 0 AAA ATPase domain Complex1_LYR PF05347.10 AEO54030.1 - 4.2e-09 36.0 0.1 7.5e-09 35.2 0.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 AEO54030.1 - 3.9e-07 30.1 0.2 5.5e-07 29.7 0.1 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 AEO54030.1 - 2.6e-05 24.6 0.1 3.4e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 Complex1_LYR-like PMT_C PF11647.3 AEO54030.1 - 0.026 14.1 0.2 1.7 8.3 0.0 2.5 3 0 0 3 3 3 0 C-terminal region of Pasteurella multocida toxin residues 569-1285 Patatin PF01734.17 AEO54031.1 - 2.3e-23 83.1 0.0 5.2e-23 82.0 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase TPR_12 PF13424.1 AEO54031.1 - 1.4e-15 56.9 6.7 2e-06 27.6 0.2 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat NB-ARC PF00931.17 AEO54031.1 - 4.1e-10 38.9 0.0 8.2e-10 37.9 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_11 PF13414.1 AEO54031.1 - 2.2e-08 33.5 6.3 6.1e-05 22.5 0.4 3.5 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 AEO54031.1 - 9.5e-06 25.1 11.9 0.052 13.4 0.2 5.2 5 0 0 5 5 4 2 Tetratricopeptide repeat AAA_16 PF13191.1 AEO54031.1 - 3.5e-05 23.8 0.1 0.00029 20.8 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain TPR_14 PF13428.1 AEO54031.1 - 5.3e-05 23.5 13.4 3 8.7 0.5 6.3 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 AEO54031.1 - 0.00015 21.2 6.2 0.26 10.9 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 AEO54031.1 - 0.0019 18.5 7.3 0.39 11.0 0.3 4.4 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 AEO54031.1 - 0.0037 17.6 9.7 7.6 7.2 0.0 5.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 AEO54031.1 - 0.0061 16.2 2.0 7.3 6.6 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat AAA_22 PF13401.1 AEO54031.1 - 0.046 13.8 0.0 0.16 12.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain Coatomer_E PF04733.9 AEO54031.1 - 0.073 12.2 0.1 0.19 10.8 0.0 1.6 2 0 0 2 2 2 0 Coatomer epsilon subunit AAA PF00004.24 AEO54031.1 - 0.085 13.0 0.0 0.28 11.3 0.0 1.9 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) TPR_10 PF13374.1 AEO54031.1 - 0.16 11.9 12.2 4.6 7.3 0.5 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 AEO54031.1 - 0.39 10.6 7.4 2.6 8.0 0.3 4.5 4 0 0 4 4 3 0 Tetratricopeptide repeat Pyr_redox_3 PF13738.1 AEO54032.1 - 7.1e-21 75.2 0.0 1.5e-20 74.0 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AEO54032.1 - 3.4e-10 39.7 0.0 1e-09 38.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 AEO54032.1 - 3.6e-10 38.6 0.0 2.1e-09 36.1 0.0 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 AEO54032.1 - 7.8e-06 25.0 0.0 0.011 14.6 0.0 3.5 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 AEO54032.1 - 1.5e-05 24.9 0.0 0.00074 19.4 0.0 2.3 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 AEO54032.1 - 3e-05 23.8 0.1 0.0031 17.3 0.0 3.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 AEO54032.1 - 0.16 11.0 0.0 0.66 9.0 0.0 1.9 2 0 0 2 2 2 0 Thi4 family Mito_fiss_reg PF05308.6 AEO54033.1 - 7.5 5.8 5.8 14 4.9 4.0 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator DDHD PF02862.12 AEO54034.1 - 0.0079 16.0 8.6 0.0097 15.7 6.0 1.2 1 0 0 1 1 1 1 DDHD domain PAP1 PF08601.5 AEO54034.1 - 0.38 10.3 19.9 0.45 10.1 13.8 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 DUF1675 PF07897.6 AEO54034.1 - 3.4 7.4 14.8 4.3 7.1 10.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) SpoIIE PF07228.7 AEO54035.1 - 5.3e-13 49.0 0.5 7.2e-12 45.4 0.3 2.1 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 AEO54035.1 - 1.2e-11 44.4 0.0 0.00015 21.2 0.0 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 AEO54035.1 - 3.3e-10 39.7 0.1 6.6e-10 38.7 0.1 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C RCR PF12273.3 AEO54036.1 - 2.8e-10 40.8 15.7 8.7e-10 39.2 10.1 1.9 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Shisa PF13908.1 AEO54036.1 - 1.4 9.0 7.7 8.4 6.5 5.3 2.1 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator tRNA-synt_2c PF01411.14 AEO54038.1 - 8.4e-205 681.2 0.1 6.7e-204 678.2 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 AEO54038.1 - 3.7e-17 61.9 0.2 8.4e-17 60.7 0.1 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 AEO54038.1 - 0.014 15.0 0.2 0.055 13.1 0.1 2.1 1 0 0 1 1 1 0 DHHA1 domain Methyltransf_28 PF02636.12 AEO54039.1 - 7.2e-39 133.6 0.0 3.6e-38 131.4 0.0 1.9 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.11 AEO54039.1 - 0.011 14.6 0.0 0.019 13.8 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase PALP PF00291.20 AEO54040.1 - 3.7e-56 190.6 0.9 4.4e-56 190.3 0.6 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF3042 PF11240.3 AEO54040.1 - 4.9 7.0 5.8 10 5.9 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3042) TFIIS_M PF07500.9 AEO54041.1 - 7.7e-25 87.2 0.4 1.1e-23 83.4 0.0 2.2 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 AEO54041.1 - 5.2e-19 67.6 6.1 8.6e-19 66.8 4.2 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 AEO54041.1 - 1.1e-15 56.8 0.0 3.1e-15 55.4 0.0 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DUF4407 PF14362.1 AEO54043.1 - 0.013 14.5 0.1 0.022 13.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) p450 PF00067.17 AEO54044.1 - 3.4e-71 240.1 0.0 4.3e-71 239.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BSP_II PF05432.6 AEO54046.1 - 0.00022 20.6 3.1 0.00022 20.6 2.1 2.4 2 1 0 2 2 2 1 Bone sialoprotein II (BSP-II) DUF4642 PF15484.1 AEO54046.1 - 0.02 14.8 0.4 0.035 14.0 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4642) NOA36 PF06524.7 AEO54046.1 - 0.042 13.1 2.2 0.081 12.1 1.5 1.4 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.7 AEO54046.1 - 0.1 10.5 2.0 0.15 9.9 1.4 1.2 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 AEO54046.1 - 0.19 11.2 10.9 0.3 10.6 7.5 1.3 1 0 0 1 1 1 0 Nucleoplasmin tRNA-synt_2 PF00152.15 AEO54047.1 - 8.4e-101 337.0 0.0 1.1e-100 336.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 AEO54047.1 - 0.005 16.4 0.2 0.014 15.0 0.1 1.6 1 1 1 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) ANTH PF07651.11 AEO54048.1 - 3e-70 236.1 0.5 4e-70 235.7 0.4 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 AEO54048.1 - 6.3e-08 32.5 0.0 1.2e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 ENTH domain MAT1 PF06391.8 AEO54049.1 - 3.1e-29 101.9 2.4 4e-29 101.6 1.7 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 AEO54049.1 - 0.00026 20.5 5.7 0.00062 19.3 4.0 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF572 PF04502.8 AEO54049.1 - 0.00073 18.8 3.4 0.00092 18.5 2.4 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-C3HC4_3 PF13920.1 AEO54049.1 - 0.00086 18.9 6.5 0.0013 18.3 4.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO54049.1 - 0.0027 17.4 9.2 0.04 13.6 7.0 2.1 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 AEO54049.1 - 0.006 16.5 8.0 0.018 15.0 5.7 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Sporozoite_P67 PF05642.6 AEO54049.1 - 0.021 12.7 0.0 0.024 12.5 0.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen zf-RING_2 PF13639.1 AEO54049.1 - 0.026 14.3 7.4 0.094 12.5 5.2 1.8 1 1 1 2 2 2 0 Ring finger domain MRP-S26 PF14943.1 AEO54049.1 - 0.066 12.7 16.9 0.12 11.9 11.7 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 eIF-3_zeta PF05091.7 AEO54049.1 - 0.17 10.4 4.1 0.22 10.1 2.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Selenoprotein_S PF06936.6 AEO54049.1 - 0.32 10.5 7.1 0.54 9.7 4.9 1.4 1 0 0 1 1 1 0 Selenoprotein S (SelS) zf-RING_UBOX PF13445.1 AEO54049.1 - 0.32 10.7 3.4 0.66 9.7 2.3 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 AEO54049.1 - 0.45 10.4 6.0 1.1 9.2 4.2 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING CAF-1_p150 PF11600.3 AEO54049.1 - 0.62 9.4 16.6 0.96 8.7 11.5 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal zf-RING_4 PF14570.1 AEO54049.1 - 1 8.9 10.3 15 5.2 7.6 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-UDP PF14569.1 AEO54049.1 - 1.3 8.8 5.8 0.2 11.4 0.8 2.0 2 0 0 2 2 2 0 Zinc-binding RING-finger CS PF04969.11 AEO54050.1 - 4.3e-16 59.2 0.1 1e-15 57.9 0.0 1.7 2 0 0 2 2 2 1 CS domain Prefoldin_3 PF13758.1 AEO54051.1 - 2.6e-32 110.5 0.5 7.4e-32 109.0 0.3 1.8 1 0 0 1 1 1 1 Prefoldin subunit DUF3835 PF12927.2 AEO54051.1 - 2.9e-23 82.6 17.1 4.1e-19 69.3 0.0 5.5 7 1 1 8 8 8 2 Domain of unknown function (DUF3835) MIS13 PF08202.6 AEO54051.1 - 0.00015 20.9 0.8 0.00033 19.8 0.5 1.5 1 0 0 1 1 1 1 Mis12-Mtw1 protein family SPX PF03105.14 AEO54051.1 - 0.036 13.8 5.6 0.041 13.6 2.5 2.1 1 1 1 2 2 2 0 SPX domain Vfa1 PF08432.5 AEO54052.1 - 0.0038 17.2 22.3 0.0078 16.2 15.4 1.5 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Daxx PF03344.10 AEO54052.1 - 0.0075 14.8 20.6 0.013 14.0 14.3 1.4 1 0 0 1 1 1 1 Daxx Family CAF-1_p150 PF11600.3 AEO54052.1 - 0.016 14.5 47.1 0.042 13.2 32.7 1.7 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF2413 PF10310.4 AEO54052.1 - 0.027 13.2 16.9 0.046 12.5 11.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Ycf1 PF05758.7 AEO54052.1 - 0.16 9.6 15.4 0.22 9.2 10.6 1.1 1 0 0 1 1 1 0 Ycf1 FNIP_M PF14637.1 AEO54052.1 - 0.18 11.3 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 Folliculin-interacting protein middle domain CDC27 PF09507.5 AEO54052.1 - 0.78 8.8 36.0 1.5 7.9 25.0 1.5 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RR_TM4-6 PF06459.7 AEO54052.1 - 0.8 9.5 27.0 1.6 8.5 18.7 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SAPS PF04499.10 AEO54052.1 - 0.91 8.0 10.7 1.4 7.4 7.4 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.7 AEO54052.1 - 0.93 7.3 28.4 1.4 6.7 19.7 1.1 1 0 0 1 1 1 0 Nop14-like family Tim54 PF11711.3 AEO54052.1 - 1.2 7.6 19.3 2.7 6.4 13.4 1.6 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CDC45 PF02724.9 AEO54052.1 - 1.4 6.8 18.5 2.1 6.2 12.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Borrelia_P83 PF05262.6 AEO54052.1 - 2.7 6.1 18.9 4 5.5 13.1 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF2151 PF10221.4 AEO54052.1 - 3.6 5.6 14.6 5.4 5.0 10.1 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator DDHD PF02862.12 AEO54052.1 - 6.9 6.3 14.8 19 4.9 10.3 1.8 1 0 0 1 1 1 0 DDHD domain Pox_Ag35 PF03286.9 AEO54052.1 - 7.1 6.0 24.3 19 4.6 16.8 1.8 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Far-17a_AIG1 PF04750.9 AEO54053.1 - 9.5e-05 21.6 14.5 0.00015 21.0 10.0 1.3 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein DUF2897 PF11446.3 AEO54053.1 - 0.028 14.2 0.0 0.057 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) MBOAT PF03062.14 AEO54054.1 - 6.2e-43 147.1 12.6 6.2e-43 147.1 8.7 2.0 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family F-box-like PF12937.2 AEO54055.1 - 1.3e-10 40.8 1.3 2.1e-10 40.1 0.1 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 AEO54055.1 - 0.00033 20.2 0.3 0.00075 19.0 0.2 1.7 1 0 0 1 1 1 1 F-box domain Trs65 PF12735.2 AEO54055.1 - 1.2 8.3 3.8 1.9 7.6 2.6 1.2 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 DUF4557 PF15101.1 AEO54055.1 - 8.7 6.1 13.5 17 5.1 9.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) GST_N_3 PF13417.1 AEO54056.1 - 8.1e-15 54.8 0.0 1.5e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 AEO54056.1 - 6.5e-12 45.2 0.0 1.2e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 AEO54056.1 - 9.7e-11 41.6 0.0 1.9e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 AEO54056.1 - 8.3e-08 32.1 0.0 1.4e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 AEO54056.1 - 1.5e-05 24.7 0.1 3.8e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 AEO54056.1 - 0.00018 21.9 0.1 0.00023 21.5 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 AEO54056.1 - 0.004 17.5 0.0 0.0073 16.6 0.0 1.4 1 0 0 1 1 1 1 MetRS-N binding domain Cation_efflux PF01545.16 AEO54057.1 - 3.4e-06 26.3 1.8 3.6e-06 26.2 1.3 1.0 1 0 0 1 1 1 1 Cation efflux family Cation_efflux PF01545.16 AEO54058.1 - 3.5e-38 131.2 0.0 5.1e-38 130.7 0.0 1.2 1 0 0 1 1 1 1 Cation efflux family AsnC_trans_reg PF01037.16 AEO54058.1 - 0.14 11.8 0.1 0.34 10.6 0.0 1.7 2 0 0 2 2 2 0 AsnC family DUF3176 PF11374.3 AEO54059.1 - 1.6e-23 82.7 0.0 2.8e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Toxin_51 PF15531.1 AEO54060.1 - 0.12 12.1 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Putative toxin 51 Raptor_N PF14538.1 AEO54061.1 - 0.013 15.3 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain PLA2_B PF01735.13 AEO54062.1 - 1.2e-188 627.2 0.0 1.4e-188 627.0 0.0 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Histidinol_dh PF00815.15 AEO54063.1 - 2.4e-180 599.5 6.6 3.2e-180 599.1 4.6 1.1 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 AEO54063.1 - 1.3e-25 88.8 0.0 2.5e-25 87.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 AEO54063.1 - 6.1e-10 39.2 0.1 6.1e-10 39.2 0.1 2.2 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase TFIID-31kDa PF02291.10 AEO54064.1 - 1e-24 86.7 0.0 7.8e-24 83.8 0.0 2.4 1 1 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit DUF1421 PF07223.6 AEO54064.1 - 0.00054 19.8 49.9 0.00078 19.3 34.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1421) Macoilin PF09726.4 AEO54064.1 - 0.027 12.7 5.9 0.035 12.4 4.1 1.1 1 0 0 1 1 1 0 Transmembrane protein Neur_chan_memb PF02932.11 AEO54064.1 - 3.8 7.3 9.4 5.6 6.7 6.5 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PAT1 PF09770.4 AEO54064.1 - 5.6 5.0 54.5 7.3 4.6 37.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SAGA-Tad1 PF12767.2 AEO54064.1 - 5.9 6.4 24.5 8.9 5.8 17.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit LNS2 PF08235.8 AEO54065.1 - 2e-71 238.6 0.0 3.1e-71 238.0 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 AEO54065.1 - 1.4e-39 134.2 0.0 6.1e-39 132.1 0.0 2.1 2 0 0 2 2 2 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.9 AEO54065.1 - 0.0052 16.1 0.0 0.27 10.5 0.0 2.7 3 0 0 3 3 3 1 HAD superfamily, subfamily IIIB (Acid phosphatase) fn3 PF00041.16 AEO54066.1 - 5.5e-08 32.8 0.0 1.2e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain DUF3584 PF12128.3 AEO54066.1 - 0.31 8.3 25.3 0.57 7.4 17.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Cmc1 PF08583.5 AEO54067.1 - 4.4e-16 58.3 6.2 4.4e-16 58.3 4.3 1.7 2 0 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF559 PF04480.7 AEO54067.1 - 0.013 15.1 0.2 0.024 14.2 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF559) CHCH PF06747.8 AEO54067.1 - 0.014 15.2 2.1 0.15 12.0 1.0 2.4 1 1 2 3 3 3 0 CHCH domain NST1 PF13945.1 AEO54067.1 - 0.34 10.9 4.6 0.061 13.3 0.6 1.7 2 0 0 2 2 2 0 Salt tolerance down-regulator YqzE PF14038.1 AEO54067.1 - 0.67 9.7 3.7 0.55 10.0 1.1 2.0 1 1 0 1 1 1 0 YqzE-like protein DAO PF01266.19 AEO54068.1 - 9e-24 84.0 0.0 1.6e-23 83.1 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 AEO54068.1 - 6.3e-05 23.3 0.1 0.00013 22.2 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AEO54068.1 - 0.00021 21.2 0.7 0.00052 19.9 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.11 AEO54068.1 - 0.00059 19.3 0.0 0.00093 18.6 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.9 AEO54068.1 - 0.0011 18.8 0.1 0.0017 18.2 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 AEO54068.1 - 0.0011 17.8 0.4 0.0019 17.1 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 AEO54068.1 - 0.0021 17.1 0.6 0.0032 16.5 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.13 AEO54068.1 - 0.0044 16.7 0.2 0.0044 16.7 0.2 1.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 AEO54068.1 - 0.051 12.9 1.5 0.079 12.3 1.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_3 PF13738.1 AEO54068.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 AEO54068.1 - 0.12 11.1 0.1 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.9 AEO54068.1 - 0.13 10.7 0.8 0.17 10.2 0.5 1.1 1 0 0 1 1 1 0 HI0933-like protein Utp11 PF03998.8 AEO54070.1 - 1.6e-58 198.4 19.5 1.8e-58 198.2 13.5 1.0 1 0 0 1 1 1 1 Utp11 protein DUF572 PF04502.8 AEO54070.1 - 0.25 10.4 18.8 0.4 9.8 6.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) Folate_carrier PF01770.13 AEO54070.1 - 0.32 9.4 1.4 0.52 8.7 1.0 1.2 1 0 0 1 1 1 0 Reduced folate carrier Bd3614_N PF14442.1 AEO54070.1 - 2.1 8.2 11.7 0.066 13.1 2.2 2.3 2 1 0 2 2 2 0 Bd3614-like deaminase N-terminal DUF2201_N PF13203.1 AEO54070.1 - 3.1 6.8 9.2 0.18 10.9 2.9 1.6 2 0 0 2 2 2 0 Putative metallopeptidase domain Glyco_hydro_47 PF01532.15 AEO54071.1 - 9e-167 555.2 0.0 1.1e-166 555.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 tRNA-synt_2b PF00587.20 AEO54072.1 - 5.1e-50 169.4 0.0 8.7e-50 168.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Maf PF02545.9 AEO54072.1 - 2.3e-40 137.8 0.2 3.9e-30 104.4 0.0 2.4 2 0 0 2 2 2 2 Maf-like protein HGTP_anticodon PF03129.15 AEO54072.1 - 2.3e-06 27.4 0.0 4.9e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain FLO_LFY PF01698.11 AEO54072.1 - 0.018 13.8 1.3 0.028 13.2 0.9 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Pox_Ag35 PF03286.9 AEO54072.1 - 0.32 10.4 8.9 0.57 9.6 6.2 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FAM176 PF14851.1 AEO54072.1 - 1.1 8.9 4.8 1.4 8.5 2.3 1.8 2 0 0 2 2 2 0 FAM176 family Tim54 PF11711.3 AEO54072.1 - 3.4 6.1 7.4 5.4 5.5 5.1 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Ribosomal_60s PF00428.14 AEO54072.1 - 7.7 6.9 14.9 2.8 8.3 8.2 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein Amidohydro_1 PF01979.15 AEO54074.1 - 5.9e-62 210.2 1.6 8.6e-62 209.7 1.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 AEO54074.1 - 4.5e-55 184.9 1.7 9.3e-55 183.9 1.2 1.6 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.15 AEO54074.1 - 5.1e-40 135.3 0.0 8.8e-40 134.6 0.0 1.4 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.13 AEO54074.1 - 5.8e-12 45.4 0.0 1.1e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_5 PF13594.1 AEO54074.1 - 3.4e-07 29.9 4.2 1.1e-06 28.3 2.9 1.9 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 AEO54074.1 - 0.0015 17.8 0.0 0.12 11.5 0.0 2.4 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_2 PF04909.9 AEO54074.1 - 0.015 14.8 0.0 0.037 13.5 0.0 1.7 2 0 0 2 2 2 0 Amidohydrolase HMG_box PF00505.14 AEO54076.1 - 1.8e-07 31.3 0.1 4.7e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 AEO54076.1 - 1.7e-05 25.0 0.3 6.2e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 HMG-box domain Het-C PF07217.6 AEO54077.1 - 2.6e-268 891.2 0.0 3.3e-268 890.9 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C DUF3414 PF11894.3 AEO54077.1 - 0.031 11.2 0.2 0.043 10.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3414) Glyco_hydro_45 PF02015.11 AEO54078.1 - 3.6e-94 314.4 17.3 4.2e-94 314.2 12.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 APG6 PF04111.7 AEO54079.1 - 2.2e-127 424.4 0.0 2.7e-127 424.1 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 DUF972 PF06156.8 AEO54079.1 - 0.019 15.2 0.5 0.042 14.1 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF342 PF03961.8 AEO54079.1 - 0.036 12.5 2.3 0.051 11.9 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) V_ATPase_I PF01496.14 AEO54079.1 - 0.084 10.7 4.4 0.11 10.3 3.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 AEO54079.1 - 0.15 11.6 12.1 0.31 10.6 8.4 1.5 1 0 0 1 1 1 0 IncA protein DUF3450 PF11932.3 AEO54079.1 - 0.54 9.4 8.3 1.2 8.3 5.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Atg14 PF10186.4 AEO54079.1 - 0.93 8.3 9.6 5.7 5.7 6.6 2.0 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 GAS PF13851.1 AEO54079.1 - 3.8 6.6 11.1 12 4.9 7.1 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding V-SNARE PF05008.10 AEO54080.1 - 8.5e-22 77.1 2.4 8.5e-22 77.1 1.7 2.2 2 1 1 3 3 3 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 AEO54080.1 - 1.1e-14 54.2 3.1 1.1e-14 54.2 2.1 2.0 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 AEO54080.1 - 0.001 18.6 1.9 0.0016 18.1 0.6 2.0 2 0 0 2 2 2 1 Sec20 Spc7 PF08317.6 AEO54080.1 - 0.0016 17.2 4.1 0.16 10.6 0.2 2.1 2 0 0 2 2 2 2 Spc7 kinetochore protein Unstab_antitox PF09720.5 AEO54080.1 - 0.022 14.4 0.1 0.072 12.7 0.1 1.9 1 1 0 1 1 1 0 Putative addiction module component DUF3829 PF12889.2 AEO54080.1 - 0.027 13.6 1.6 0.036 13.2 0.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3829) Spectrin PF00435.16 AEO54080.1 - 0.033 14.4 4.1 0.16 12.2 0.1 2.7 1 1 2 3 3 3 0 Spectrin repeat Use1 PF09753.4 AEO54080.1 - 0.082 12.3 7.8 1.3 8.3 5.4 2.6 1 1 0 1 1 1 0 Membrane fusion protein Use1 YqjK PF13997.1 AEO54080.1 - 0.095 12.8 6.1 0.64 10.2 0.1 3.2 3 0 0 3 3 3 0 YqjK-like protein Prominin PF05478.6 AEO54080.1 - 0.64 7.4 5.0 6.5 4.1 3.5 2.0 1 1 0 1 1 1 0 Prominin Metal_resist PF13801.1 AEO54080.1 - 5.5 6.9 14.1 0.093 12.7 3.1 2.8 1 1 1 2 2 2 0 Heavy-metal resistance Scm3 PF10384.4 AEO54081.1 - 3.7e-20 71.1 0.0 6.8e-20 70.3 0.0 1.5 1 0 0 1 1 1 1 Centromere protein Scm3 Dicty_REP PF05086.7 AEO54081.1 - 0.39 8.4 1.2 0.56 7.8 0.8 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pkinase PF00069.20 AEO54082.1 - 1.9e-60 204.1 0.1 2.3e-60 203.9 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO54082.1 - 5.2e-20 71.6 0.0 7.3e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AEO54082.1 - 3e-08 33.6 0.0 9.6e-06 25.4 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 AEO54082.1 - 0.0074 15.8 0.1 0.018 14.5 0.1 1.7 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 AEO54082.1 - 0.074 12.1 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 AEO54082.1 - 0.086 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DUF3395 PF11875.3 AEO54083.1 - 2e-12 46.9 0.0 1.1e-06 28.3 0.0 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF3395) Fungal_trans PF04082.13 AEO54084.1 - 5.3e-14 51.7 1.5 8.1e-14 51.1 1.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO54084.1 - 6.4e-09 35.5 11.1 1.3e-08 34.5 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AlaDh_PNT_N PF05222.10 AEO54085.1 - 1.4e-28 99.6 0.0 2e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 AEO54085.1 - 7e-17 61.4 0.0 9.8e-17 61.0 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain IMPDH PF00478.20 AEO54086.1 - 5.7e-135 449.7 2.9 6.8e-135 449.4 2.0 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 AEO54086.1 - 1.8e-17 62.8 0.1 7.6e-09 35.2 0.1 2.5 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.13 AEO54086.1 - 3.1e-10 39.4 1.7 3.3e-08 32.7 0.5 2.2 2 0 0 2 2 2 2 FMN-dependent dehydrogenase NMO PF03060.10 AEO54086.1 - 2e-09 37.0 4.7 0.00027 20.2 2.8 2.5 2 0 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.16 AEO54086.1 - 0.00011 21.5 2.9 0.0041 16.4 0.2 2.4 1 1 1 2 2 2 2 Histidine biosynthesis protein NanE PF04131.9 AEO54086.1 - 0.022 13.7 0.2 0.04 12.8 0.1 1.4 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase PK PF00224.16 AEO54086.1 - 0.025 13.1 0.0 0.067 11.8 0.0 1.6 1 1 1 2 2 2 0 Pyruvate kinase, barrel domain B12-binding PF02310.14 AEO54086.1 - 0.052 13.4 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 B12 binding domain RasGAP_C PF03836.10 AEO54087.1 - 1.4e-48 164.1 2.2 5e-48 162.4 1.5 2.0 1 0 0 1 1 1 1 RasGAP C-terminus RasGAP PF00616.14 AEO54087.1 - 3.1e-39 134.6 0.0 8.3e-39 133.2 0.0 1.8 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.22 AEO54087.1 - 5e-19 66.0 44.9 0.013 15.0 0.8 13.7 14 0 0 14 14 14 8 IQ calmodulin-binding motif CH PF00307.26 AEO54087.1 - 2.9e-09 36.9 0.0 8.2e-09 35.4 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain MFS_1 PF07690.11 AEO54088.1 - 1.1e-31 109.8 37.2 4.3e-24 84.8 5.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO54088.1 - 3.8e-11 42.2 3.1 3.8e-11 42.2 2.1 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter TFR_dimer PF04253.10 AEO54089.1 - 3e-23 81.7 0.0 5e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 AEO54089.1 - 5.4e-14 52.3 0.0 1.3e-13 51.0 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.17 AEO54089.1 - 2.1e-08 33.7 0.2 7e-08 32.0 0.0 1.9 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.23 AEO54089.1 - 0.0079 15.7 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.10 AEO54089.1 - 0.031 13.5 0.0 0.057 12.6 0.0 1.3 1 0 0 1 1 1 0 Nicastrin GIT_SHD PF08518.6 AEO54090.1 - 3.6e-22 77.4 4.9 1.7e-13 49.6 0.7 2.7 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT Filament PF00038.16 AEO54090.1 - 0.024 14.1 32.6 0.065 12.6 4.4 2.6 3 0 0 3 3 3 0 Intermediate filament protein APG6 PF04111.7 AEO54090.1 - 0.76 8.7 38.9 0.044 12.8 14.5 2.4 1 1 1 2 2 2 0 Autophagy protein Apg6 Sec8_exocyst PF04048.9 AEO54090.1 - 2.2 7.9 15.1 5.4 6.6 0.1 4.2 4 0 0 4 4 4 0 Sec8 exocyst complex component specific domain AAA_13 PF13166.1 AEO54090.1 - 8.4 4.7 28.8 0.4 9.0 15.5 2.0 2 1 0 2 2 2 0 AAA domain Ssu72 PF04722.8 AEO54091.1 - 1.7e-83 278.7 0.0 2e-83 278.5 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein SH3_9 PF14604.1 AEO54092.1 - 1.5e-08 34.1 0.2 2.6e-08 33.2 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 AEO54092.1 - 2.2e-08 33.3 0.0 3.8e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 AEO54092.1 - 2.9e-05 23.4 0.0 2.9e-05 23.4 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain NAD_binding_1 PF00175.16 AEO54093.1 - 3e-31 108.2 0.0 8e-31 106.8 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 AEO54093.1 - 5.3e-21 74.5 0.0 1.1e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 AEO54093.1 - 2.2e-09 37.4 0.0 6.6e-05 22.8 0.0 2.6 3 0 0 3 3 3 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 AEO54093.1 - 0.0075 16.2 0.0 0.02 14.8 0.0 1.7 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain Terminase_2 PF03592.11 AEO54093.1 - 0.029 14.6 0.1 0.053 13.7 0.1 1.3 1 0 0 1 1 1 0 Terminase small subunit DUF3807 PF12720.2 AEO54094.1 - 4e-46 157.3 4.9 4.7e-46 157.0 3.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) DUF488 PF04343.8 AEO54095.1 - 0.21 11.9 3.9 0.72 10.2 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function, DUF488 V-SNARE PF05008.10 AEO54095.1 - 0.24 11.5 2.2 0.51 10.5 0.4 2.2 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Atg14 PF10186.4 AEO54096.1 - 9.6e-85 284.1 0.0 1.1e-84 283.9 0.0 1.0 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 HAUS-augmin3 PF14932.1 AEO54096.1 - 0.004 16.3 0.5 0.0058 15.8 0.4 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 Mnd1 PF03962.10 AEO54096.1 - 0.0069 16.0 4.6 0.011 15.4 3.2 1.3 1 0 0 1 1 1 1 Mnd1 family ATG16 PF08614.6 AEO54096.1 - 0.089 12.6 8.2 0.14 12.0 5.7 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) TBPIP PF07106.8 AEO54096.1 - 0.14 11.6 2.0 0.21 11.0 1.4 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) AAA_13 PF13166.1 AEO54096.1 - 0.19 10.1 1.6 0.24 9.8 1.1 1.1 1 0 0 1 1 1 0 AAA domain APG6 PF04111.7 AEO54096.1 - 1.1 8.2 4.2 1.6 7.7 2.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4149 PF13664.1 AEO54097.1 - 0.2 11.7 2.2 0.42 10.7 1.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) Spc7 PF08317.6 AEO54098.1 - 2.9e-93 312.1 16.0 4.1e-93 311.6 11.1 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc7_N PF15402.1 AEO54098.1 - 8e-86 288.9 21.2 8e-86 288.9 14.7 1.5 2 0 0 2 2 2 1 N-terminus of kinetochore NMS complex subunit Spc7 Spc7_C2 PF15577.1 AEO54098.1 - 1.5e-13 50.1 0.0 3e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Spc7_C2 V_ATPase_I PF01496.14 AEO54098.1 - 1.9 6.2 8.2 2.6 5.7 5.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fib_alpha PF08702.5 AEO54098.1 - 2.8 8.0 9.5 0.22 11.6 3.2 1.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.1 AEO54098.1 - 5.1 5.9 8.7 9.8 5.0 6.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3135 PF11333.3 AEO54098.1 - 5.7 7.1 9.5 0.065 13.4 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) APG6 PF04111.7 AEO54098.1 - 7.1 5.5 14.4 2.8 6.8 8.3 1.6 1 1 0 1 1 1 0 Autophagy protein Apg6 Spc7_N PF15402.1 AEO54099.1 - 4.8e-139 465.0 40.4 5.7e-113 378.7 21.7 2.0 1 1 1 2 2 2 2 N-terminus of kinetochore NMS complex subunit Spc7 Ribosomal_S17 PF00366.15 AEO54100.1 - 4.6e-31 106.6 1.0 7.5e-31 105.9 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 SWI-SNF_Ssr4 PF08549.5 AEO54101.1 - 1.7e-242 806.5 10.4 2.2e-242 806.2 7.2 1.0 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1750) 6PGD PF00393.14 AEO54102.1 - 7.1e-135 448.8 0.0 8.9e-135 448.5 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 AEO54102.1 - 3.7e-52 176.4 0.0 5.6e-52 175.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 AEO54102.1 - 0.082 12.9 0.0 0.25 11.3 0.0 1.9 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase RRM_1 PF00076.17 AEO54103.1 - 6.8e-18 64.0 0.1 1.1e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO54103.1 - 1e-12 47.8 0.0 1.6e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO54103.1 - 2.4e-05 24.0 0.1 4.2e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 AEO54103.1 - 0.098 12.1 0.2 0.19 11.2 0.1 1.4 1 0 0 1 1 1 0 Ribonuclease B OB domain TPT PF03151.11 AEO54104.1 - 8.7e-32 109.8 13.1 8.7e-32 109.8 9.1 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 AEO54104.1 - 0.0017 17.3 25.0 0.0032 16.4 16.2 2.0 1 1 1 2 2 2 1 UAA transporter family EamA PF00892.15 AEO54104.1 - 0.0039 17.2 42.1 0.032 14.2 11.6 3.3 2 2 1 3 3 3 2 EamA-like transporter family Glyco_hydro_15 PF00723.16 AEO54105.1 - 1.2e-52 178.9 0.0 2.1e-50 171.5 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 Bromo_TP PF07524.8 AEO54106.1 - 2.3e-05 24.0 0.0 6e-05 22.6 0.0 1.6 2 0 0 2 2 2 1 Bromodomain associated DUF3186 PF11382.3 AEO54106.1 - 0.00015 21.0 0.0 0.00021 20.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3186) FAM101 PF15068.1 AEO54106.1 - 0.68 9.3 4.8 1.1 8.6 3.3 1.3 1 0 0 1 1 1 0 FAM101 family TAFII55_N PF04658.8 AEO54107.1 - 1.2e-51 174.3 0.0 1.2e-51 174.3 0.0 1.9 2 0 0 2 2 2 1 TAFII55 protein conserved region Nop14 PF04147.7 AEO54107.1 - 0.045 11.6 38.0 0.062 11.2 23.7 2.1 2 0 0 2 2 2 0 Nop14-like family Prothymosin PF03247.9 AEO54107.1 - 0.21 11.7 59.7 0.19 11.8 17.7 3.5 3 0 0 3 3 3 0 Prothymosin/parathymosin family CENP-T PF15511.1 AEO54107.1 - 1.4 8.0 36.8 0.3 10.2 17.7 2.2 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T Vma12 PF11712.3 AEO54107.1 - 3.5 7.3 5.8 0.91 9.2 0.9 2.3 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase BTV_NS2 PF04514.7 AEO54107.1 - 4 6.2 25.5 0.14 11.0 4.8 3.0 3 0 0 3 3 3 0 Bluetongue virus non-structural protein NS2 Adaptin_binding PF10199.4 AEO54107.1 - 6.8 6.9 32.8 6.2 7.1 4.4 3.3 3 0 0 3 3 3 0 Alpha and gamma adaptin binding protein p34 Ribosomal_L37 PF08561.5 AEO54108.1 - 1.1e-30 105.0 5.7 2.5e-23 81.4 0.2 2.2 2 0 0 2 2 2 2 Mitochondrial ribosomal protein L37 NDUFB10 PF10249.4 AEO54109.1 - 0.002 18.2 0.2 0.0025 17.9 0.2 1.3 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 HWE_HK PF07536.9 AEO54109.1 - 0.047 14.1 0.0 0.088 13.2 0.0 1.4 1 0 0 1 1 1 0 HWE histidine kinase RRM_1 PF00076.17 AEO54110.1 - 9.4e-44 146.9 0.0 1.7e-21 75.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO54110.1 - 1.1e-35 121.3 0.0 1.3e-19 69.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO54110.1 - 1.9e-21 75.6 0.0 7.4e-12 44.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 AEO54110.1 - 0.0053 16.4 0.0 0.53 10.0 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif WH2 PF02205.15 AEO54113.1 - 1.3e-10 40.4 2.2 3e-10 39.3 0.2 2.4 2 0 0 2 2 2 1 WH2 motif CHORD PF04968.7 AEO54116.1 - 5.7e-51 170.6 17.1 2.4e-25 88.5 2.6 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.11 AEO54116.1 - 1.5e-13 51.0 0.1 2.4e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 CS domain DUF836 PF05768.9 AEO54117.1 - 9.3e-15 54.6 0.0 1.1e-14 54.4 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.19 AEO54117.1 - 8.1e-06 25.7 0.0 1.7e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.1 AEO54117.1 - 0.015 15.5 0.0 0.018 15.2 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain Gallidermin PF02052.10 AEO54117.1 - 0.039 14.0 0.0 0.073 13.1 0.0 1.4 1 0 0 1 1 1 0 Gallidermin Fungal_trans_2 PF11951.3 AEO54117.1 - 0.095 11.2 0.0 0.095 11.2 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain HpcH_HpaI PF03328.9 AEO54118.1 - 1.1e-33 116.0 0.0 1.3e-33 115.8 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family DUF2156 PF09924.4 AEO54118.1 - 0.0044 15.8 0.0 0.0069 15.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) PEP_mutase PF13714.1 AEO54118.1 - 0.01 15.0 0.2 4.7 6.3 0.0 3.2 3 0 0 3 3 3 0 Phosphoenolpyruvate phosphomutase PEP-utilizers_C PF02896.13 AEO54118.1 - 0.039 12.8 0.5 3.8 6.3 0.0 2.6 2 1 0 2 2 2 0 PEP-utilising enzyme, TIM barrel domain DUF1045 PF06299.7 AEO54118.1 - 0.041 13.5 0.0 0.092 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1045) LSM PF01423.17 AEO54119.1 - 1.3e-14 53.4 0.1 1.6e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 LSM domain IU_nuc_hydro PF01156.14 AEO54120.1 - 8.4e-58 196.0 0.1 2e-46 158.6 0.0 2.1 2 0 0 2 2 2 2 Inosine-uridine preferring nucleoside hydrolase DinB_2 PF12867.2 AEO54123.1 - 0.077 13.3 0.2 0.32 11.3 0.0 1.9 2 0 0 2 2 2 0 DinB superfamily Sporozoite_P67 PF05642.6 AEO54123.1 - 0.21 9.3 5.3 0.25 9.1 3.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Med3 PF11593.3 AEO54123.1 - 1.7 7.8 4.8 4.4 6.4 3.4 1.6 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal SSP160 PF06933.6 AEO54123.1 - 2.4 6.0 11.8 3.2 5.6 8.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.3 AEO54123.1 - 2.9 7.6 6.8 5.2 6.8 4.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Rhomboid PF01694.17 AEO54124.1 - 1e-24 87.2 6.0 2.4e-24 86.0 4.2 1.6 1 0 0 1 1 1 1 Rhomboid family Med2 PF11214.3 AEO54124.1 - 4.3 7.4 6.6 11 6.0 4.6 1.7 1 0 0 1 1 1 0 Mediator complex subunit 2 PhoD PF09423.5 AEO54125.1 - 3.6e-08 32.3 0.0 6e-07 28.3 0.0 2.2 2 0 0 2 2 2 1 PhoD-like phosphatase TFIIA PF03153.8 AEO54125.1 - 4.3 7.1 9.5 7.5 6.3 6.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HLH PF00010.21 AEO54126.1 - 6.5e-15 54.5 0.6 2e-14 53.0 0.4 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Aldedh PF00171.17 AEO54127.1 - 4.4e-108 361.5 0.0 5.6e-108 361.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Herpes_gE PF02480.11 AEO54128.1 - 0.055 11.7 0.0 0.084 11.1 0.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E CBFD_NFYB_HMF PF00808.18 AEO54129.1 - 6.7e-07 29.2 0.3 1e-06 28.6 0.2 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 AEO54129.1 - 1.4e-05 25.0 0.2 2.6e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CAF-1_p150 PF11600.3 AEO54129.1 - 0.011 15.1 4.8 0.015 14.7 3.4 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SR-25 PF10500.4 AEO54129.1 - 0.032 13.7 6.4 0.036 13.5 4.4 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Bromo_TP PF07524.8 AEO54129.1 - 0.046 13.4 0.0 0.071 12.8 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated Lipase_GDSL PF00657.17 AEO54129.1 - 0.063 13.0 0.0 0.071 12.9 0.0 1.1 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase MRI PF15325.1 AEO54129.1 - 0.21 12.5 8.4 0.34 11.8 5.8 1.3 1 0 0 1 1 1 0 Modulator of retrovirus infection HpaP PF09483.5 AEO54129.1 - 0.24 11.3 7.3 0.46 10.4 5.1 1.4 1 1 0 1 1 1 0 Type III secretion protein (HpaP) Macoilin PF09726.4 AEO54129.1 - 0.36 9.0 4.0 0.36 9.0 2.8 1.1 1 0 0 1 1 1 0 Transmembrane protein CRC_subunit PF08624.5 AEO54130.1 - 6.2e-54 181.6 0.0 9.3e-54 181.1 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit RNB PF00773.14 AEO54131.1 - 4.7e-95 318.6 0.0 6.7e-95 318.0 0.0 1.2 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 AEO54131.1 - 9.4e-10 38.7 1.7 1.8e-09 37.7 0.0 2.4 3 0 0 3 3 3 1 PIN domain OB_RNB PF08206.6 AEO54131.1 - 0.022 14.2 0.0 0.087 12.3 0.0 2.1 1 0 0 1 1 1 0 Ribonuclease B OB domain GN3L_Grn1 PF08701.6 AEO54132.1 - 6.8e-25 86.7 17.8 1.5e-24 85.6 12.4 1.6 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 AEO54132.1 - 7.9e-20 70.9 0.1 4.5e-13 49.1 0.0 2.7 2 1 1 3 3 3 2 50S ribosome-binding GTPase GTP_EFTU PF00009.22 AEO54132.1 - 5.2e-07 29.2 0.0 0.016 14.6 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 AEO54132.1 - 8.6e-07 28.9 8.8 0.0032 17.3 1.4 4.0 3 1 0 3 3 3 2 Dynamin family FeoB_N PF02421.13 AEO54132.1 - 0.0019 17.5 0.1 0.032 13.5 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 AEO54132.1 - 0.0024 17.0 0.1 0.0042 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 AEO54132.1 - 0.026 15.0 0.2 2.7 8.5 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein ArgK PF03308.11 AEO54132.1 - 0.034 12.9 3.1 0.058 12.1 0.0 2.2 2 0 0 2 2 2 0 ArgK protein AAA_16 PF13191.1 AEO54132.1 - 0.097 12.6 0.2 0.097 12.6 0.2 2.8 2 1 0 2 2 2 0 AAA ATPase domain TFIIA PF03153.8 AEO54132.1 - 0.24 11.2 21.0 0.37 10.6 14.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BTV_NS2 PF04514.7 AEO54132.1 - 1.4 7.6 14.1 2.1 7.1 9.8 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Nop14 PF04147.7 AEO54132.1 - 2 6.2 33.7 2.8 5.7 23.4 1.1 1 0 0 1 1 1 0 Nop14-like family FLO_LFY PF01698.11 AEO54132.1 - 7.9 5.2 12.8 14 4.3 8.9 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein Daxx PF03344.10 AEO54132.1 - 9 4.6 19.7 14 3.9 13.7 1.3 1 0 0 1 1 1 0 Daxx Family HAD_2 PF13419.1 AEO54133.1 - 4e-17 62.9 0.0 5.1e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 AEO54133.1 - 8.6e-10 38.1 0.0 1.5e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 AEO54133.1 - 2.5e-09 37.8 0.0 2.2e-07 31.5 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 AEO54133.1 - 0.013 15.6 0.0 0.025 14.7 0.0 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 AEO54133.1 - 0.09 12.6 0.1 2.2 8.2 0.0 2.6 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase GHL6 PF14871.1 AEO54133.1 - 0.092 12.7 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 Homeobox PF00046.24 AEO54134.1 - 4.7e-15 54.9 1.8 9.7e-15 53.9 1.2 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 AEO54134.1 - 0.0033 17.1 0.1 0.0073 15.9 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain Pkinase PF00069.20 AEO54135.1 - 1.6e-68 230.7 0.0 8.9e-67 224.9 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO54135.1 - 5.4e-36 124.0 0.0 9.7e-36 123.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO54135.1 - 4.6e-07 29.0 0.0 1.1e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AEO54135.1 - 0.02 14.6 0.0 0.046 13.4 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family MSA-2c PF12238.3 AEO54135.1 - 1.9 8.1 8.2 21 4.7 0.1 2.9 3 0 0 3 3 3 0 Merozoite surface antigen 2c SLD3 PF08639.5 AEO54136.1 - 2.2e-129 432.3 2.4 4.3e-129 431.3 1.6 1.5 1 0 0 1 1 1 1 DNA replication regulator SLD3 Trs65 PF12735.2 AEO54137.1 - 1e-85 287.7 0.0 2e-85 286.8 0.0 1.5 2 0 0 2 2 2 1 TRAPP trafficking subunit Trs65 FF PF01846.14 AEO54138.1 - 4.1e-51 170.7 7.1 1.7e-13 50.2 0.0 7.0 6 1 0 6 6 6 6 FF domain WW PF00397.21 AEO54138.1 - 2.7e-19 68.6 13.5 1.3e-10 40.9 1.8 2.6 2 0 0 2 2 2 2 WW domain ABC_tran PF00005.22 AEO54139.1 - 6.6e-35 120.3 0.0 1.1e-16 61.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 AEO54139.1 - 3.6e-14 53.4 10.1 0.00011 22.3 0.0 4.7 3 2 1 4 4 4 3 AAA domain SMC_N PF02463.14 AEO54139.1 - 8.4e-09 34.9 2.5 0.0042 16.3 0.0 3.5 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 AEO54139.1 - 4.1e-08 32.6 0.1 0.19 10.7 0.0 4.4 5 0 0 5 5 5 2 AAA ATPase domain AAA_17 PF13207.1 AEO54139.1 - 2e-06 28.6 0.3 0.07 13.9 0.0 3.0 2 2 0 2 2 2 2 AAA domain AAA PF00004.24 AEO54139.1 - 3.3e-06 27.3 0.0 0.0062 16.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 AEO54139.1 - 5e-06 26.8 0.1 0.15 12.3 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 AEO54139.1 - 1.3e-05 25.2 0.0 0.0076 16.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 AEO54139.1 - 0.00017 20.8 0.0 0.37 9.9 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MobB PF03205.9 AEO54139.1 - 0.00031 20.4 0.8 0.064 12.9 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 AEO54139.1 - 0.00063 19.8 0.1 0.39 10.9 0.0 2.6 2 0 0 2 2 2 1 RNA helicase SRP54 PF00448.17 AEO54139.1 - 0.0011 18.4 2.5 0.056 12.8 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain NACHT PF05729.7 AEO54139.1 - 0.0011 18.6 0.8 0.31 10.6 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_23 PF13476.1 AEO54139.1 - 0.0012 19.2 0.1 0.13 12.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain VirE PF05272.6 AEO54139.1 - 0.0014 18.1 0.1 1.8 7.9 0.0 2.7 2 0 0 2 2 2 2 Virulence-associated protein E UPF0079 PF02367.12 AEO54139.1 - 0.0016 18.0 0.3 0.016 14.7 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_16 PF13191.1 AEO54139.1 - 0.0018 18.2 0.5 0.36 10.8 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 AEO54139.1 - 0.002 18.0 0.0 0.14 12.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 AEO54139.1 - 0.0036 17.2 0.5 0.23 11.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.12 AEO54139.1 - 0.0037 16.6 0.1 1.3 8.3 0.0 2.6 2 0 0 2 2 2 1 Thymidylate kinase AAA_29 PF13555.1 AEO54139.1 - 0.0057 16.1 2.0 1.8 8.1 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Rad17 PF03215.10 AEO54139.1 - 0.0087 14.7 0.0 0.14 10.8 0.0 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_5 PF07728.9 AEO54139.1 - 0.019 14.6 0.2 1.3 8.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 AEO54139.1 - 0.02 14.3 0.5 4 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.1 AEO54139.1 - 0.023 13.1 0.0 0.023 13.1 0.0 2.0 3 0 0 3 3 3 0 AAA domain Miro PF08477.8 AEO54139.1 - 0.023 15.1 0.1 1.9 9.0 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein PduV-EutP PF10662.4 AEO54139.1 - 0.024 14.1 2.0 0.075 12.5 0.0 2.7 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.17 AEO54139.1 - 0.032 13.0 0.1 1.9 7.2 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain SbcCD_C PF13558.1 AEO54139.1 - 0.048 13.5 0.0 7 6.6 0.0 3.2 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.1 AEO54139.1 - 0.09 12.6 1.8 9.5 6.1 0.1 3.4 2 2 0 2 2 2 0 AAA domain AAA_30 PF13604.1 AEO54139.1 - 0.15 11.6 0.2 2.6 7.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 AEO54139.1 - 0.28 10.8 2.7 7.6 6.2 0.1 2.5 2 0 0 2 2 2 0 NTPase AAA_24 PF13479.1 AEO54139.1 - 0.38 10.2 1.9 2.8 7.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain SNF2_N PF00176.18 AEO54140.1 - 7.9e-65 218.5 0.0 1.3e-64 217.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 AEO54140.1 - 4.7e-28 96.6 1.8 2.7e-15 55.7 0.1 3.2 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 AEO54140.1 - 8.6e-15 54.3 0.0 2.4e-14 52.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain POR PF01558.13 AEO54140.1 - 0.05 13.5 0.3 0.34 10.8 0.0 2.2 2 0 0 2 2 2 0 Pyruvate ferredoxin/flavodoxin oxidoreductase SIR2 PF02146.12 AEO54141.1 - 2e-27 96.0 0.0 5.4e-27 94.6 0.0 1.7 1 1 0 1 1 1 1 Sir2 family Zn-ribbon_8 PF09723.5 AEO54141.1 - 0.25 11.3 1.4 0.59 10.1 0.9 1.6 1 0 0 1 1 1 0 Zinc ribbon domain SAGA-Tad1 PF12767.2 AEO54141.1 - 6.7 6.2 7.6 12 5.4 5.3 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Med16 PF11635.3 AEO54142.1 - 1e-82 278.3 0.0 1.2e-82 278.1 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 DUF3500 PF12006.3 AEO54143.1 - 7.8e-104 346.9 0.0 9.1e-104 346.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) ABM PF03992.11 AEO54144.1 - 1.1e-06 28.6 0.0 2.6e-05 24.1 0.0 2.4 2 0 0 2 2 2 1 Antibiotic biosynthesis monooxygenase Abhydrolase_3 PF07859.8 AEO54145.1 - 0.017 14.7 0.1 0.017 14.6 0.0 1.0 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 AEO54145.1 - 0.036 13.4 0.0 0.038 13.4 0.0 1.0 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Cutinase PF01083.17 AEO54145.1 - 0.075 12.7 0.0 0.075 12.7 0.0 1.2 1 0 0 1 1 1 0 Cutinase DUF1749 PF08538.5 AEO54145.1 - 0.15 10.8 0.1 0.16 10.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Sugarporin_N PF11471.3 AEO54146.1 - 0.0044 16.6 1.7 0.0044 16.6 1.2 2.1 2 0 0 2 2 2 1 Maltoporin periplasmic N-terminal extension NPV_P10 PF05531.7 AEO54146.1 - 0.012 15.8 3.8 3 8.1 0.1 2.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF3584 PF12128.3 AEO54146.1 - 0.014 12.7 11.0 0.026 11.8 7.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4349 PF14257.1 AEO54146.1 - 0.09 11.9 10.1 0.063 12.4 4.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) V_ATPase_I PF01496.14 AEO54146.1 - 0.095 10.5 0.4 0.13 10.0 0.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 AEO54146.1 - 0.13 11.8 14.2 0.23 11.0 9.5 1.5 1 1 0 1 1 1 0 IncA protein AAA_13 PF13166.1 AEO54146.1 - 0.17 10.3 4.5 0.23 9.9 3.1 1.1 1 0 0 1 1 1 0 AAA domain DUF1664 PF07889.7 AEO54146.1 - 0.78 9.5 3.8 3.1 7.5 2.0 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Spc7 PF08317.6 AEO54146.1 - 0.86 8.1 12.3 0.34 9.5 5.0 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Reo_sigmaC PF04582.7 AEO54146.1 - 2.3 7.3 8.7 1.8 7.6 3.1 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein APG6 PF04111.7 AEO54146.1 - 2.7 6.9 11.8 3.1 6.7 6.3 1.9 1 1 1 2 2 2 0 Autophagy protein Apg6 ATG16 PF08614.6 AEO54146.1 - 5.4 6.7 13.9 26 4.5 9.7 2.0 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Glyco_hydro_16 PF00722.16 AEO54148.1 - 4.2e-08 32.7 0.1 1.9e-07 30.5 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Adeno_shaft PF00608.12 AEO54148.1 - 0.053 13.1 0.1 0.12 11.9 0.1 1.7 1 0 0 1 1 1 0 Adenoviral fibre protein (repeat/shaft region) Glyco_transf_34 PF05637.7 AEO54149.1 - 1.1e-68 231.2 1.0 1.4e-68 230.9 0.7 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Peptidase_M22 PF00814.20 AEO54150.1 - 1.8e-42 145.6 0.0 6e-29 101.3 0.2 3.3 2 1 0 2 2 2 2 Glycoprotease family UPF0016 PF01169.14 AEO54150.1 - 0.089 12.9 0.1 0.35 11.0 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein family UPF0016 PhoU PF01895.14 AEO54150.1 - 0.25 11.8 0.7 0.55 10.7 0.5 1.5 1 0 0 1 1 1 0 PhoU domain Herpes_US9 PF06072.6 AEO54150.1 - 9.7 6.1 12.1 0.055 13.3 1.7 2.2 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 Proteasome PF00227.21 AEO54151.1 - 1.8e-49 167.5 0.1 2.2e-49 167.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF3222 PF11519.3 AEO54151.1 - 0.09 12.7 0.4 1.6 8.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3222) DUF554 PF04474.7 AEO54151.1 - 0.096 11.8 0.1 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF554) DUF1752 PF08550.5 AEO54152.1 - 3.3e-10 39.3 2.9 6.6e-10 38.3 2.0 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) PBP1_TM PF14812.1 AEO54152.1 - 0.12 12.6 7.6 1.4 9.2 1.3 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4611 PF15387.1 AEO54152.1 - 2.6 8.2 7.7 0.77 9.9 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Nucleoplasmin PF03066.10 AEO54152.1 - 2.7 7.5 6.9 5.3 6.5 0.2 2.3 2 0 0 2 2 2 0 Nucleoplasmin Spt5_N PF11942.3 AEO54152.1 - 3.5 8.3 14.7 1.5 9.4 1.3 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Met_10 PF02475.11 AEO54153.1 - 2.9e-72 242.4 0.0 3.8e-72 242.0 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Prenyltransf PF01255.14 AEO54154.1 - 2e-09 36.9 0.0 3.8e-07 29.4 0.0 2.1 2 0 0 2 2 2 2 Putative undecaprenyl diphosphate synthase UPF0158 PF03682.8 AEO54154.1 - 0.06 12.9 0.0 0.73 9.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0158) Sec10 PF07393.6 AEO54155.1 - 1e-234 780.9 3.9 1.2e-234 780.7 2.7 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 RNB PF00773.14 AEO54156.1 - 1.1e-64 218.8 0.0 2e-64 217.9 0.0 1.4 2 0 0 2 2 2 1 RNB domain Glyco_hydro_17 PF00332.13 AEO54157.1 - 0.06 12.3 0.1 0.16 10.9 0.1 1.7 2 0 0 2 2 2 0 Glycosyl hydrolases family 17 WD40 PF00400.27 AEO54158.1 - 1.2e-09 37.6 1.1 3.3e-07 29.9 0.2 4.6 4 0 0 4 4 4 1 WD domain, G-beta repeat DUF2415 PF10313.4 AEO54158.1 - 0.012 15.3 0.0 0.12 12.0 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) TFIIIC_delta PF12657.2 AEO54158.1 - 0.059 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Transcription factor IIIC subunit delta N-term Daxx PF03344.10 AEO54158.1 - 0.27 9.6 6.8 0.39 9.1 4.7 1.1 1 0 0 1 1 1 0 Daxx Family Chitin_synth_2 PF03142.10 AEO54159.1 - 4.4e-294 975.7 0.1 4.4e-294 975.7 0.1 1.5 2 0 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.1 AEO54159.1 - 1.7e-18 67.0 3.2 7e-18 65.0 2.2 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 AEO54159.1 - 1.6e-14 54.2 0.1 2.8e-13 50.1 0.0 2.4 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 AEO54159.1 - 2.6e-14 52.7 0.2 1.6e-11 43.8 0.0 2.5 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 AEO54159.1 - 9.7e-05 21.7 0.0 0.00061 19.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 AEO54159.1 - 0.037 13.7 0.0 0.17 11.5 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 2 Sel1 PF08238.7 AEO54161.1 - 7.2e-30 102.7 29.4 6.4e-05 23.4 0.0 6.5 6 0 0 6 6 6 6 Sel1 repeat MFS_2 PF13347.1 AEO54162.1 - 5.5e-13 48.0 8.8 5.5e-13 48.0 6.1 2.3 3 0 0 3 3 3 1 MFS/sugar transport protein MFS_1_like PF12832.2 AEO54162.1 - 0.015 15.1 0.8 0.15 11.8 0.0 3.1 3 0 0 3 3 3 0 MFS_1 like family Abi PF02517.11 AEO54162.1 - 1 9.5 8.9 4.3 7.5 1.8 3.2 3 1 0 3 3 3 0 CAAX protease self-immunity HisG PF01634.13 AEO54163.1 - 1e-49 168.2 0.6 7.9e-48 162.1 0.4 2.2 1 1 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 AEO54163.1 - 6.1e-28 96.5 0.3 1.3e-27 95.5 0.2 1.6 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.6 AEO54163.1 - 0.021 14.4 0.0 1.1 8.8 0.0 2.5 2 0 0 2 2 2 0 NMT1/THI5 like MSC PF09402.5 AEO54164.1 - 2.2e-110 368.5 0.0 2.9e-110 368.1 0.0 1.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 AEO54164.1 - 1.5e-17 62.8 0.1 5.4e-17 61.0 0.0 2.0 2 0 0 2 2 2 1 HeH/LEM domain Thymopoietin PF08198.6 AEO54164.1 - 0.0046 16.4 0.1 0.011 15.1 0.0 1.6 1 0 0 1 1 1 1 Thymopoietin protein DUF3350 PF11830.3 AEO54164.1 - 0.014 15.3 2.9 1.1 9.3 0.4 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3350) HLH PF00010.21 AEO54165.1 - 5.1e-17 61.3 0.0 1.2e-16 60.0 0.0 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF45 PF01863.12 AEO54165.1 - 4.4 7.0 9.3 0.19 11.5 1.5 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF45 Glycophorin_A PF01102.13 AEO54166.1 - 1.8e-05 24.5 1.8 1.8e-05 24.5 1.3 2.3 2 0 0 2 2 2 1 Glycophorin A PAP1 PF08601.5 AEO54166.1 - 0.0022 17.7 2.6 0.0022 17.7 1.8 2.4 2 0 0 2 2 2 1 Transcription factor PAP1 TMEM154 PF15102.1 AEO54166.1 - 0.0036 17.0 0.6 0.011 15.4 0.4 1.8 1 0 0 1 1 1 1 TMEM154 protein family Alpha_GJ PF03229.8 AEO54166.1 - 0.0081 16.4 5.4 0.0081 16.4 3.8 3.4 3 0 0 3 3 3 1 Alphavirus glycoprotein J Kelch_4 PF13418.1 AEO54166.1 - 0.012 15.3 3.2 3.7 7.3 0.0 3.9 4 0 0 4 4 4 0 Galactose oxidase, central domain EphA2_TM PF14575.1 AEO54166.1 - 0.029 14.7 0.1 0.095 13.1 0.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.11 AEO54166.1 - 0.033 12.4 0.0 0.053 11.7 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Adeno_E3_CR2 PF02439.10 AEO54166.1 - 0.18 11.3 0.1 0.36 10.4 0.1 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 TAP_C PF03943.8 AEO54167.1 - 7.8e-12 44.4 0.0 1.7e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 TAP C-terminal domain LRR_4 PF12799.2 AEO54167.1 - 1.9e-06 27.3 0.0 1.6e-05 24.4 0.0 2.3 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 AEO54167.1 - 1.5e-05 24.6 0.0 2.4e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat NTF2 PF02136.15 AEO54167.1 - 0.0025 18.1 0.0 0.0064 16.8 0.0 1.7 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_8 PF13855.1 AEO54167.1 - 0.0078 15.9 0.0 0.019 14.7 0.0 1.7 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 AEO54167.1 - 0.048 13.6 0.0 0.52 10.5 0.0 2.6 2 0 0 2 2 2 0 Leucine Rich Repeat PGA_cap PF09587.5 AEO54167.1 - 0.086 12.1 0.0 1.1 8.5 0.1 2.2 1 1 1 2 2 2 0 Bacterial capsule synthesis protein PGA_cap DEAD PF00270.24 AEO54168.1 - 3.2e-20 72.3 0.0 9.6e-20 70.7 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 AEO54168.1 - 1.1e-19 71.0 0.0 2.1e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 AEO54168.1 - 1.3e-19 69.7 0.1 1.3e-19 69.7 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 AEO54168.1 - 0.0011 19.1 0.0 0.0042 17.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 AEO54168.1 - 0.012 15.1 0.6 1.6 8.0 0.0 3.3 2 2 1 3 3 3 0 AAA-like domain zf-C2H2 PF00096.21 AEO54170.1 - 1.2 9.6 14.5 0.084 13.2 3.6 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AEO54170.1 - 5.6 7.5 21.3 0.58 10.6 2.5 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger PMT PF02366.13 AEO54171.1 - 4.6e-80 268.5 17.6 4.6e-80 268.5 12.2 1.9 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 AEO54171.1 - 2.4e-17 63.1 0.1 1.5e-16 60.5 0.0 2.0 1 1 1 2 2 2 2 MIR domain Ribonuc_L-PSP PF01042.16 AEO54172.1 - 9.7e-41 138.3 0.1 1.1e-40 138.1 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Acetyltransf_1 PF00583.19 AEO54174.1 - 3.4e-11 43.0 0.0 7.8e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family MarR_2 PF12802.2 AEO54174.1 - 1.3e-09 37.5 0.1 8.1e-09 35.0 0.0 2.4 2 0 0 2 2 2 1 MarR family Acetyltransf_10 PF13673.1 AEO54174.1 - 4.3e-07 30.0 0.1 2e-06 27.9 0.0 2.0 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 AEO54174.1 - 1.5e-06 28.2 0.0 3.5e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MarR PF01047.17 AEO54174.1 - 9.5e-06 25.2 0.0 2.8e-05 23.7 0.0 1.8 2 0 0 2 2 1 1 MarR family HTH_27 PF13463.1 AEO54174.1 - 7.4e-05 23.0 0.0 0.00018 21.7 0.0 1.7 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_5 PF01022.15 AEO54174.1 - 0.00017 21.1 0.0 0.00043 19.8 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family FeoC PF09012.5 AEO54174.1 - 0.00057 19.5 0.0 0.0042 16.7 0.0 2.2 1 1 1 2 2 2 1 FeoC like transcriptional regulator HTH_20 PF12840.2 AEO54174.1 - 0.0007 19.3 0.0 0.0079 15.9 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain PadR PF03551.9 AEO54174.1 - 0.00096 18.8 0.0 0.0019 17.9 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family Rrf2 PF02082.15 AEO54174.1 - 0.0018 18.3 0.0 0.0039 17.2 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulator Acetyltransf_CG PF14542.1 AEO54174.1 - 0.0034 17.2 0.0 0.0066 16.3 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Replic_Relax PF13814.1 AEO54174.1 - 0.006 16.4 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 Replication-relaxation HxlR PF01638.12 AEO54174.1 - 0.0066 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 HxlR-like helix-turn-helix HTH_IclR PF09339.5 AEO54174.1 - 0.0096 15.4 0.1 0.14 11.7 0.0 3.0 3 0 0 3 3 3 1 IclR helix-turn-helix domain TrmB PF01978.14 AEO54174.1 - 0.012 15.2 0.0 0.044 13.4 0.0 1.9 2 0 0 2 2 1 0 Sugar-specific transcriptional regulator TrmB Acetyltransf_8 PF13523.1 AEO54174.1 - 0.014 15.3 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HTH_24 PF13412.1 AEO54174.1 - 0.02 14.2 0.0 0.047 13.0 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding FR47 PF08445.5 AEO54174.1 - 0.028 14.1 0.0 0.07 12.9 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_4 PF13420.1 AEO54174.1 - 0.038 13.9 0.0 0.066 13.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF35 PF01796.12 AEO54174.1 - 0.099 12.8 1.6 0.15 12.3 0.1 2.1 2 0 0 2 2 1 0 DUF35 OB-fold domain HTH_9 PF08221.6 AEO54174.1 - 0.11 12.3 0.1 0.57 10.0 0.0 2.1 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 AEO54174.1 - 0.13 11.7 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 TFIIE alpha subunit HTH_Crp_2 PF13545.1 AEO54174.1 - 0.13 12.0 0.0 0.33 10.7 0.0 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain p450 PF00067.17 AEO54175.1 - 1.5e-76 257.7 0.0 1.9e-76 257.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Myb_DNA-bind_6 PF13921.1 AEO54176.1 - 5.3e-06 26.4 0.1 9.6e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 AEO54176.1 - 0.0034 17.4 0.2 0.0072 16.3 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain ABC_tran PF00005.22 AEO54178.1 - 2.9e-51 173.3 0.0 2.2e-31 108.9 0.0 2.7 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 AEO54178.1 - 3.7e-22 79.0 25.9 5.7e-17 62.0 10.8 2.8 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 AEO54178.1 - 2.1e-08 33.6 0.0 0.015 14.5 0.0 4.1 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 AEO54178.1 - 9e-07 28.4 1.1 0.17 11.2 0.0 3.9 4 0 0 4 4 3 2 AAA domain AAA_29 PF13555.1 AEO54178.1 - 4.2e-06 26.1 1.2 0.024 14.1 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 AEO54178.1 - 5.2e-06 26.9 1.8 0.0018 18.6 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 AEO54178.1 - 5.8e-05 22.6 0.3 0.68 9.3 0.0 3.3 3 0 0 3 3 3 1 AAA-like domain T2SE PF00437.15 AEO54178.1 - 7.8e-05 21.7 0.0 0.022 13.6 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_16 PF13191.1 AEO54178.1 - 8.7e-05 22.5 2.1 0.4 10.6 0.2 3.6 2 1 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 AEO54178.1 - 0.00017 21.5 0.1 0.32 10.9 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.1 AEO54178.1 - 0.00018 21.5 0.0 12 5.7 0.0 3.7 4 0 0 4 4 4 0 AAA domain DUF87 PF01935.12 AEO54178.1 - 0.00022 21.1 7.4 0.0036 17.1 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_17 PF13207.1 AEO54178.1 - 0.0003 21.5 0.2 0.089 13.6 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.1 AEO54178.1 - 0.00053 20.2 0.4 0.44 10.8 0.1 2.8 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 AEO54178.1 - 0.00099 18.3 0.2 0.51 9.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 AEO54178.1 - 0.002 18.2 1.4 4.8 7.3 0.3 3.5 3 0 0 3 3 3 1 AAA domain ArgK PF03308.11 AEO54178.1 - 0.01 14.6 0.2 0.14 10.8 0.0 2.2 2 0 0 2 2 2 0 ArgK protein Miro PF08477.8 AEO54178.1 - 0.011 16.2 0.2 9.1 6.8 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein NACHT PF05729.7 AEO54178.1 - 0.05 13.2 2.9 2.6 7.6 0.5 2.7 2 0 0 2 2 2 0 NACHT domain DUF2075 PF09848.4 AEO54178.1 - 0.059 12.3 1.0 0.77 8.6 0.1 2.6 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) SbcCD_C PF13558.1 AEO54178.1 - 0.075 12.9 0.0 4.2 7.3 0.0 3.2 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.17 AEO54178.1 - 0.09 12.9 0.0 8.7 6.5 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Mg_chelatase PF01078.16 AEO54178.1 - 0.091 11.9 0.3 0.77 8.8 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.13 AEO54178.1 - 0.11 11.9 0.0 7.7 5.9 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family ATP-synt_ab PF00006.20 AEO54178.1 - 0.13 11.7 0.2 0.4 10.1 0.0 1.9 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain MobB PF03205.9 AEO54178.1 - 0.21 11.2 1.1 4.3 7.0 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 AEO54178.1 - 0.49 9.2 2.1 2.5 6.8 0.1 2.6 3 0 0 3 3 3 0 NB-ARC domain Zeta_toxin PF06414.7 AEO54178.1 - 0.81 8.7 2.6 20 4.2 0.0 2.8 3 0 0 3 3 3 0 Zeta toxin AAA_19 PF13245.1 AEO54178.1 - 2.1 8.1 6.7 4.4 7.1 0.2 3.4 3 0 0 3 3 2 0 Part of AAA domain adh_short PF00106.20 AEO54179.1 - 4.2e-26 91.8 0.0 5.8e-26 91.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO54179.1 - 1.3e-25 90.6 0.0 1.6e-25 90.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO54179.1 - 2.9e-11 43.3 0.0 4e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 AEO54179.1 - 0.0011 18.4 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 AEO54179.1 - 0.0071 16.1 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 AEO54179.1 - 0.071 12.2 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) HhH-GPD PF00730.20 AEO54180.1 - 2.1e-08 34.3 0.0 3.8e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Cytochrom_C1 PF02167.10 AEO54181.1 - 7.5e-83 277.4 0.0 9.1e-83 277.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 AEO54181.1 - 0.011 15.8 0.0 0.024 14.7 0.0 1.6 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III DAHP_synth_1 PF00793.15 AEO54182.1 - 5.8e-99 330.1 0.0 6.9e-99 329.9 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Mu-like_Pro PF10123.4 AEO54182.1 - 0.0036 16.7 0.1 0.0062 16.0 0.0 1.3 1 0 0 1 1 1 1 Mu-like prophage I protein Pro_isomerase PF00160.16 AEO54183.1 - 1.4e-50 171.5 0.0 5.5e-50 169.5 0.0 2.0 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 AEO54183.1 - 8.3e-14 50.8 1.5 2.8e-08 33.3 0.0 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat Nbas_N PF15492.1 AEO54183.1 - 0.12 11.4 0.1 8.1 5.4 0.0 2.4 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal FMN_dh PF01070.13 AEO54184.1 - 6.3e-121 403.5 0.1 7.6e-121 403.2 0.1 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.10 AEO54184.1 - 3e-05 23.3 1.3 6e-05 22.3 0.9 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.12 AEO54184.1 - 0.00029 19.8 0.1 0.00044 19.2 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 AEO54184.1 - 0.00033 19.6 0.4 0.0022 16.9 0.1 2.0 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 AEO54184.1 - 0.034 13.2 0.4 0.21 10.6 0.2 2.1 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG IGPS PF00218.16 AEO54184.1 - 0.094 11.7 0.2 0.49 9.3 0.2 1.9 1 1 1 2 2 2 0 Indole-3-glycerol phosphate synthase His_biosynth PF00977.16 AEO54184.1 - 0.095 11.9 0.1 0.36 10.0 0.1 1.9 1 1 1 2 2 2 0 Histidine biosynthesis protein Nup84_Nup100 PF04121.8 AEO54185.1 - 2.3e-69 233.8 0.0 3.5e-68 229.9 0.0 2.4 1 1 0 1 1 1 1 Nuclear pore protein 84 / 107 DUF1903 PF08991.5 AEO54186.1 - 1.4e-18 66.7 4.9 2.1e-18 66.2 3.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 AEO54186.1 - 0.059 13.2 2.3 0.11 12.4 1.6 1.4 1 0 0 1 1 1 0 CHCH domain Cmc1 PF08583.5 AEO54186.1 - 0.17 11.7 3.6 0.18 11.6 1.8 1.7 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like zf-C4 PF00105.13 AEO54186.1 - 0.57 10.4 5.2 0.48 10.6 1.4 2.2 1 1 1 2 2 2 0 Zinc finger, C4 type (two domains) Rad60-SLD PF11976.3 AEO54187.1 - 6.4e-21 73.8 0.1 8e-21 73.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 AEO54187.1 - 1.8e-09 36.8 0.1 2.2e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family HH_signal PF01085.13 AEO54187.1 - 0.047 13.2 0.0 0.051 13.1 0.0 1.0 1 0 0 1 1 1 0 Hedgehog amino-terminal signalling domain LIM PF00412.17 AEO54188.1 - 3.3e-26 91.1 24.1 1.6e-09 37.6 1.0 3.6 4 0 0 4 4 4 3 LIM domain zf-dskA_traR PF01258.12 AEO54188.1 - 0.072 12.8 0.3 0.072 12.8 0.2 4.9 6 0 0 6 6 6 0 Prokaryotic dksA/traR C4-type zinc finger DUF2321 PF10083.4 AEO54188.1 - 2 7.9 8.7 0.06 12.8 0.3 2.4 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2321) Nudix_N_2 PF14803.1 AEO54188.1 - 2.7 7.7 16.7 1.4 8.6 0.5 5.0 5 0 0 5 5 5 0 Nudix N-terminal MFS_1 PF07690.11 AEO54189.1 - 9.1e-21 73.9 63.2 7.6e-12 44.5 19.8 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 AEO54189.1 - 1e-07 30.7 30.2 4.3e-06 25.3 8.3 2.2 1 1 1 2 2 2 2 MFS/sugar transport protein Ligase_CoA PF00549.14 AEO54190.1 - 2.8e-18 65.9 0.0 7.3e-18 64.6 0.0 1.7 1 0 0 1 1 1 1 CoA-ligase Lipoprotein_15 PF03640.10 AEO54190.1 - 0.15 11.5 0.0 0.33 10.4 0.0 1.5 1 0 0 1 1 1 0 Secreted repeat of unknown function CHCH PF06747.8 AEO54191.1 - 0.00085 19.1 0.7 0.0016 18.2 0.5 1.5 1 1 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 AEO54191.1 - 0.0078 16.2 1.8 0.021 14.8 1.3 1.7 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Dynamin_M PF01031.15 AEO54192.1 - 8.4e-115 382.6 0.0 2e-114 381.3 0.0 1.6 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 AEO54192.1 - 1.2e-55 187.9 0.1 3.1e-55 186.5 0.0 1.8 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 AEO54192.1 - 3.7e-31 106.8 2.8 3.7e-31 106.8 2.0 2.1 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 AEO54192.1 - 0.0008 19.3 0.1 0.0035 17.2 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 AEO54192.1 - 0.011 16.1 0.0 0.055 13.9 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein F-box PF00646.28 AEO54193.1 - 0.0019 17.8 0.0 0.0045 16.6 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 AEO54193.1 - 0.0046 16.6 0.1 0.0099 15.5 0.0 1.5 1 0 0 1 1 1 1 F-box-like Alpha-amylase PF00128.19 AEO54195.1 - 3.4e-69 233.6 0.1 4.8e-69 233.1 0.1 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain CBM_20 PF00686.14 AEO54195.1 - 1.3e-32 111.2 1.2 2.6e-32 110.3 0.8 1.5 1 0 0 1 1 1 1 Starch binding domain DUF1966 PF09260.6 AEO54195.1 - 5e-32 109.8 0.1 1.3e-31 108.4 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Fungal_trans PF04082.13 AEO54196.1 - 2.5e-21 75.7 0.3 4.7e-21 74.8 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glutaredoxin PF00462.19 AEO54197.1 - 3e-17 62.3 0.0 1.5e-16 60.1 0.0 2.1 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 AEO54197.1 - 5.4e-15 54.9 0.0 1.2e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 AEO54197.1 - 0.0012 19.0 0.1 0.59 10.3 0.1 3.4 1 1 1 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 AEO54197.1 - 0.0052 16.8 0.0 3.9 7.6 0.0 2.7 1 1 1 2 2 2 2 Thioredoxin-like POM121 PF15229.1 AEO54197.1 - 0.014 14.7 0.1 0.023 14.1 0.1 1.2 1 0 0 1 1 1 0 POM121 family HyaE PF07449.6 AEO54197.1 - 0.11 12.4 0.0 0.6 10.0 0.0 2.1 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.1 AEO54197.1 - 0.13 12.1 0.0 0.96 9.3 0.0 2.5 3 0 0 3 3 3 0 Thioredoxin domain Phosducin PF02114.11 AEO54197.1 - 0.13 10.9 0.0 0.23 10.1 0.0 1.4 1 1 0 1 1 1 0 Phosducin CYSTM PF12734.2 AEO54198.1 - 4.6e-10 39.4 26.7 4.6e-10 39.4 18.5 5.6 3 2 0 3 3 3 1 Cysteine-rich TM module stress tolerance SH3_9 PF14604.1 AEO54199.1 - 1.5e-30 104.5 1.9 3.1e-14 52.2 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 AEO54199.1 - 1.1e-24 85.5 2.4 5.8e-12 44.8 0.2 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 AEO54199.1 - 1.9e-16 59.2 0.0 1.3e-07 30.9 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.15 AEO54199.1 - 8.9e-12 44.9 0.0 1.5e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Mod_r PF07200.8 AEO54200.1 - 1e-11 44.9 2.1 2.1e-11 43.9 1.5 1.5 1 1 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein HA PF03457.9 AEO54200.1 - 3.5 7.7 11.3 5.7 7.1 3.0 3.4 2 1 1 3 3 3 0 Helicase associated domain F-box PF00646.28 AEO54202.1 - 1.9e-06 27.3 0.9 4.1e-06 26.2 0.6 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 AEO54202.1 - 0.0031 17.1 0.2 0.0031 17.1 0.2 2.0 2 0 0 2 2 2 1 F-box-like AT_hook PF02178.14 AEO54203.1 - 2.1 8.2 20.1 6 6.8 4.1 3.1 2 0 0 2 2 2 0 AT hook motif V-ATPase_C PF03223.10 AEO54204.1 - 5.6e-116 387.4 0.0 6.3e-116 387.3 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C YjgF_endoribonc PF14588.1 AEO54204.1 - 0.047 13.6 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 YjgF/chorismate_mutase-like, putative endoribonuclease APS_kinase PF01583.15 AEO54205.1 - 3.1e-70 234.8 0.0 4.8e-70 234.2 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase 4HBT PF03061.17 AEO54205.1 - 1.4e-08 34.7 0.0 2.7e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily AAA_33 PF13671.1 AEO54205.1 - 1e-06 28.6 0.0 2.4e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AEO54205.1 - 1.9e-05 25.4 0.0 3.7e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AEO54205.1 - 0.0002 21.6 0.0 0.0005 20.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 AEO54205.1 - 0.0023 17.1 0.0 0.0035 16.6 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.1 AEO54205.1 - 0.081 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain CBF PF03914.12 AEO54207.1 - 5.4e-47 159.2 2.0 1.2e-46 158.1 0.1 2.5 2 0 0 2 2 2 1 CBF/Mak21 family tRNA-synt_2b PF00587.20 AEO54208.1 - 2.8e-33 114.9 0.0 4.2e-33 114.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 AEO54208.1 - 1.5e-07 31.2 0.0 2.5e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain HTH_29 PF13551.1 AEO54209.1 - 0.0024 17.9 0.0 0.0029 17.7 0.0 1.1 1 0 0 1 1 1 1 Winged helix-turn helix ASFV_p27 PF06556.6 AEO54209.1 - 0.025 14.4 1.5 0.035 14.0 1.0 1.3 1 1 0 1 1 1 0 IAP-like protein p27 C-terminus HTH_23 PF13384.1 AEO54210.1 - 0.088 12.4 0.3 0.12 12.0 0.2 1.2 1 0 0 1 1 1 0 Homeodomain-like domain RVT_1 PF00078.22 AEO54211.1 - 1.3e-07 31.2 1.5 1.3e-07 31.1 1.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RHH_4 PF13467.1 AEO54212.1 - 0.083 12.7 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Ribbon-helix-helix domain UCH PF00443.24 AEO54213.1 - 2.7e-40 138.2 0.0 5e-35 120.9 0.0 2.4 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AEO54213.1 - 3.9e-12 46.2 0.0 1.4e-08 34.5 0.0 2.5 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Oxysterol_BP PF01237.13 AEO54214.1 - 5.4e-90 301.4 0.0 6.6e-90 301.1 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein GFO_IDH_MocA PF01408.17 AEO54215.1 - 2.7e-13 50.4 0.0 9.1e-13 48.7 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 AEO54215.1 - 9.3e-06 25.4 0.0 2.1e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain RNase_T PF00929.19 AEO54216.1 - 2.2e-17 63.8 0.0 8.5e-17 61.9 0.0 1.7 2 0 0 2 2 2 1 Exonuclease PGM_PMM_I PF02878.11 AEO54217.1 - 4.7e-32 110.3 0.0 7.1e-32 109.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 AEO54217.1 - 5.4e-25 87.6 0.0 1.1e-24 86.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 AEO54217.1 - 1.7e-15 57.1 0.0 3.9e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 AEO54217.1 - 1.1e-08 34.9 0.0 2.5e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain HMG_box PF00505.14 AEO54219.1 - 1.2e-25 89.5 1.1 1.9e-25 88.9 0.8 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 AEO54219.1 - 3.5e-19 68.9 1.8 5.6e-19 68.2 1.2 1.3 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 AEO54219.1 - 0.00078 19.1 0.3 0.0015 18.2 0.2 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box 5 DUF1014 PF06244.7 AEO54219.1 - 0.019 15.1 0.2 0.049 13.8 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1014) DEADboxA PF12343.3 AEO54219.1 - 0.14 12.4 2.3 0.65 10.2 1.6 2.0 1 1 0 1 1 1 0 Cold shock protein DEAD box A CENP-H PF05837.7 AEO54220.1 - 2.4e-17 63.0 1.1 5e-17 62.0 0.1 1.9 2 1 0 2 2 2 1 Centromere protein H (CENP-H) Seryl_tRNA_N PF02403.17 AEO54220.1 - 0.08 12.9 0.1 0.42 10.6 0.0 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Rop-like PF05082.8 AEO54220.1 - 0.42 10.1 2.7 0.65 9.4 0.1 2.6 3 0 0 3 3 3 0 Rop-like ATG11 PF10377.4 AEO54221.1 - 1.5e-40 138.0 0.3 9.6e-40 135.4 0.1 2.7 2 0 0 2 2 2 1 Autophagy-related protein 11 ADIP PF11559.3 AEO54221.1 - 0.0096 15.8 65.8 0.29 11.0 3.0 8.5 5 2 3 8 8 8 4 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.4 AEO54221.1 - 0.075 12.8 78.8 0.025 14.4 14.5 7.3 4 2 2 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fez1 PF06818.10 AEO54221.1 - 0.32 11.0 60.5 0.64 10.0 13.4 5.1 1 1 3 4 4 4 0 Fez1 IncA PF04156.9 AEO54221.1 - 2.4 7.7 80.8 0.052 13.1 16.8 6.2 2 1 2 5 5 5 0 IncA protein Reo_sigmaC PF04582.7 AEO54221.1 - 4.5 6.3 19.7 0.044 12.9 0.4 4.5 4 1 1 5 5 5 0 Reovirus sigma C capsid protein AATase PF07247.7 AEO54222.1 - 1.8e-16 59.7 0.0 4.6e-15 55.1 0.0 2.0 1 1 0 1 1 1 1 Alcohol acetyltransferase Ribosomal_L9_N PF01281.14 AEO54222.1 - 2.8e-05 23.2 0.0 5.6e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Condensation PF00668.15 AEO54222.1 - 0.025 13.4 0.3 0.39 9.5 0.0 2.1 2 0 0 2 2 2 0 Condensation domain Ribosomal_L9_C PF03948.9 AEO54222.1 - 0.041 13.9 0.0 0.19 11.8 0.0 2.0 2 1 1 3 3 3 0 Ribosomal protein L9, C-terminal domain EutA PF06277.6 AEO54222.1 - 0.14 10.7 0.1 0.2 10.2 0.1 1.1 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutA DUF3203 PF11462.3 AEO54224.1 - 0.0012 18.6 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3203) LSM PF01423.17 AEO54225.1 - 5.4e-20 70.7 0.2 6.1e-20 70.5 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 AEO54225.1 - 0.00017 21.4 0.1 0.0002 21.2 0.1 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain IceA2 PF05862.6 AEO54225.1 - 0.083 12.6 0.3 0.18 11.5 0.2 1.6 1 0 0 1 1 1 0 Helicobacter pylori IceA2 protein LSM14 PF12701.2 AEO54225.1 - 0.092 12.5 0.1 0.11 12.2 0.1 1.1 1 0 0 1 1 1 0 Scd6-like Sm domain SPAN PF02510.9 AEO54225.1 - 0.14 11.1 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Surface presentation of antigens protein HSP20 PF00011.16 AEO54226.1 - 7e-14 51.5 0.0 4.6e-12 45.6 0.0 2.3 1 1 0 1 1 1 1 Hsp20/alpha crystallin family HCV_capsid PF01543.12 AEO54226.1 - 0.44 10.5 3.6 0.48 10.4 0.1 2.4 3 0 0 3 3 3 0 Hepatitis C virus capsid protein YTH PF04146.10 AEO54227.1 - 2.4e-57 192.4 0.0 3.1e-57 192.0 0.0 1.1 1 0 0 1 1 1 1 YT521-B-like domain DUF2457 PF10446.4 AEO54227.1 - 0.0032 16.2 4.5 0.0049 15.6 3.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) RRM_6 PF14259.1 AEO54227.1 - 0.0039 17.1 0.0 0.0077 16.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AEO54227.1 - 0.0051 16.4 0.0 0.013 15.1 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO54227.1 - 0.081 12.7 0.1 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nucleoplasmin PF03066.10 AEO54227.1 - 0.11 12.0 2.8 0.19 11.2 1.9 1.3 1 0 0 1 1 1 0 Nucleoplasmin CDC45 PF02724.9 AEO54227.1 - 0.14 10.1 3.2 0.19 9.7 2.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 AEO54227.1 - 0.33 8.8 2.4 0.37 8.6 1.7 1.1 1 0 0 1 1 1 0 Nop14-like family PBP1_TM PF14812.1 AEO54227.1 - 0.49 10.7 6.0 1.2 9.5 4.2 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Spt5_N PF11942.3 AEO54227.1 - 2.1 9.0 11.4 3.9 8.1 7.9 1.4 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal DUF4611 PF15387.1 AEO54227.1 - 2.5 8.2 7.0 5.5 7.2 4.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) p47_phox_C PF08944.6 AEO54228.1 - 1 9.6 4.1 3.7 7.8 2.8 2.1 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain Proteasome PF00227.21 AEO54229.1 - 9.3e-31 106.5 0.2 4e-30 104.5 0.1 2.0 1 1 1 2 2 2 1 Proteasome subunit PI3_PI4_kinase PF00454.22 AEO54230.1 - 1.7e-41 142.2 0.0 4.8e-41 140.7 0.0 1.8 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 AEO54230.1 - 6e-23 80.9 0.0 1.3e-22 79.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Cation_efflux PF01545.16 AEO54231.1 - 9.2e-32 110.2 13.8 1.1e-30 106.6 9.6 2.0 1 1 0 1 1 1 1 Cation efflux family DMRL_synthase PF00885.14 AEO54232.1 - 2.6e-47 160.0 0.0 1.8e-27 95.7 0.0 2.0 2 0 0 2 2 2 2 6,7-dimethyl-8-ribityllumazine synthase HATPase_c_3 PF13589.1 AEO54233.1 - 9.3e-14 51.2 0.0 1.5e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 AEO54233.1 - 7e-12 45.0 0.0 1.4e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.14 AEO54233.1 - 1.8e-10 40.3 0.0 3.1e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain TRP PF06011.7 AEO54234.1 - 3.6e-90 302.6 21.5 2e-89 300.1 14.9 1.9 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 AEO54234.1 - 1.6e-30 106.0 0.0 2.3e-30 105.4 0.0 1.2 1 0 0 1 1 1 1 ML-like domain WD40 PF00400.27 AEO54237.1 - 1.1e-13 50.5 0.7 0.89 9.5 0.1 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat RNA_pol_Rpb4 PF03874.11 AEO54238.1 - 5.7e-28 97.2 1.4 7.4e-28 96.9 1.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 CPL PF08144.6 AEO54240.1 - 9.3e-18 64.4 0.0 4.9e-17 62.1 0.0 2.2 2 0 0 2 2 2 1 CPL (NUC119) domain RWD PF05773.17 AEO54241.1 - 5.1e-23 81.1 0.3 8.4e-23 80.4 0.2 1.4 1 0 0 1 1 1 1 RWD domain FdhE PF04216.7 AEO54241.1 - 0.52 9.9 3.2 0.65 9.6 2.2 1.2 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation GN3L_Grn1 PF08701.6 AEO54241.1 - 6.6 6.7 10.8 0.36 10.7 2.0 2.4 2 0 0 2 2 2 0 GNL3L/Grn1 putative GTPase TPR_16 PF13432.1 AEO54242.1 - 3.3e-11 43.5 3.8 3.2e-05 24.4 1.1 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 AEO54242.1 - 7.4e-08 32.3 9.7 0.55 11.0 0.0 6.6 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 AEO54242.1 - 1.7e-07 30.5 0.4 0.023 14.4 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 AEO54242.1 - 1.8e-07 30.9 6.0 0.00034 20.4 0.4 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 AEO54242.1 - 2.4e-07 30.1 0.0 0.11 12.4 0.0 5.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 AEO54242.1 - 4.7e-06 26.8 3.4 0.089 13.1 0.0 4.2 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 AEO54242.1 - 0.00013 21.5 0.1 1.1 8.9 0.0 4.0 2 2 4 6 6 6 3 TPR repeat TPR_6 PF13174.1 AEO54242.1 - 0.0018 18.5 2.4 59 4.4 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.1 AEO54242.1 - 0.0082 15.9 2.3 0.15 11.9 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF550 PF04447.7 AEO54242.1 - 0.028 14.0 1.3 0.3 10.7 1.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF550) TPR_17 PF13431.1 AEO54242.1 - 0.041 14.0 0.0 71 3.9 0.0 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 AEO54242.1 - 0.078 12.7 0.0 1.2 9.1 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 AEO54242.1 - 0.093 12.3 0.0 3.8 7.2 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 AEO54242.1 - 0.14 12.6 13.7 0.72 10.4 0.0 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat CFEM PF05730.6 AEO54243.1 - 0.0017 18.1 4.6 0.0038 17.0 3.2 1.5 1 0 0 1 1 1 1 CFEM domain Mucin PF01456.12 AEO54243.1 - 0.021 14.5 24.3 0.39 10.4 16.8 2.1 1 1 0 1 1 1 0 Mucin-like glycoprotein PAP1 PF08601.5 AEO54243.1 - 2.1 7.9 17.7 2.6 7.6 12.2 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Herpes_BLLF1 PF05109.8 AEO54243.1 - 5 4.9 32.7 6.3 4.6 22.6 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) SOG2 PF10428.4 AEO54243.1 - 8.9 4.8 18.4 12 4.4 12.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein MutS_V PF00488.16 AEO54244.1 - 1.9e-52 178.0 0.0 4.1e-52 176.9 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 AEO54244.1 - 5.5e-19 68.7 0.8 1.1e-18 67.7 0.6 1.5 1 0 0 1 1 1 1 MutS domain III AAA_29 PF13555.1 AEO54244.1 - 0.056 12.9 0.0 0.21 11.1 0.0 2.0 1 0 0 1 1 1 0 P-loop containing region of AAA domain RHD3 PF05879.7 AEO54244.1 - 0.099 10.5 0.1 0.14 10.0 0.1 1.1 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) FliT PF05400.8 AEO54244.1 - 1.5 9.2 9.2 1.1 9.6 1.5 3.1 2 0 0 2 2 2 0 Flagellar protein FliT MMgT PF10270.4 AEO54245.1 - 8.1e-36 122.6 0.0 9.3e-36 122.4 0.0 1.0 1 0 0 1 1 1 1 Membrane magnesium transporter HMG_box PF00505.14 AEO54246.1 - 8.5e-11 41.9 2.6 2.2e-10 40.6 1.8 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box MAT_Alpha1 PF04769.7 AEO54246.1 - 0.004 16.5 0.1 0.0097 15.2 0.0 1.6 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG_box_2 PF09011.5 AEO54246.1 - 0.032 14.6 1.4 0.032 14.6 0.9 2.1 2 0 0 2 2 2 0 HMG-box domain AflR PF08493.5 AEO54246.1 - 0.75 8.7 8.0 0.023 13.7 0.6 1.9 2 0 0 2 2 2 0 Aflatoxin regulatory protein PHD PF00628.24 AEO54247.1 - 6.9e-09 35.2 8.9 1.5e-08 34.2 6.2 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 AEO54247.1 - 0.0019 17.4 5.4 0.0038 16.5 3.7 1.5 1 0 0 1 1 1 1 PHD-finger DDE_1 PF03184.14 AEO54248.1 - 1.2e-32 112.8 0.0 1.4e-32 112.6 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 AEO54248.1 - 0.00094 18.9 0.0 0.0013 18.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease MBT PF02820.13 AEO54248.1 - 0.1 12.5 0.1 1.2 9.0 0.0 2.1 2 0 0 2 2 2 0 mbt repeat Ion_trans PF00520.26 AEO54249.1 - 5.4e-103 342.4 75.9 3.6e-34 117.7 2.7 5.3 5 1 0 5 5 5 4 Ion transport protein DUF2722 PF10846.3 AEO54249.1 - 0.0013 17.8 2.1 0.0021 17.1 1.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) FCP1_C PF09309.5 AEO54249.1 - 0.081 12.2 4.6 0.18 11.1 3.2 1.5 1 0 0 1 1 1 0 FCP1, C-terminal EF-hand_1 PF00036.27 AEO54249.1 - 0.096 12.0 0.0 0.3 10.4 0.0 1.9 1 0 0 1 1 1 0 EF hand JSRP PF15312.1 AEO54249.1 - 0.16 11.9 1.6 0.34 10.9 0.0 2.5 2 0 0 2 2 2 0 Junctional sarcoplasmic reticulum protein Paf1 PF03985.8 AEO54249.1 - 0.64 8.7 2.6 0.95 8.1 1.8 1.1 1 0 0 1 1 1 0 Paf1 FimP PF09766.4 AEO54249.1 - 7.6 5.4 7.8 12 4.8 5.4 1.1 1 0 0 1 1 1 0 Fms-interacting protein Cyclin_N PF00134.18 AEO54252.1 - 2.9e-43 146.4 0.2 6.8e-43 145.2 0.0 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 AEO54252.1 - 1.5e-33 115.2 0.0 2.9e-33 114.3 0.0 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain Ribosomal_L2_C PF03947.13 AEO54253.1 - 5.5e-46 155.5 2.4 2.9e-45 153.2 1.7 2.1 1 1 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 AEO54253.1 - 3.7e-28 97.2 0.3 7.2e-28 96.3 0.2 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain PAP2 PF01569.16 AEO54254.1 - 1.3e-19 70.1 8.2 1.3e-19 70.1 2.2 2.7 2 1 0 2 2 2 1 PAP2 superfamily CK_II_beta PF01214.13 AEO54255.1 - 3.5e-73 245.0 0.1 4.5e-73 244.6 0.1 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit DUF3381 PF11861.3 AEO54255.1 - 0.032 13.7 2.5 0.057 12.9 1.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Nucleoplasmin PF03066.10 AEO54255.1 - 0.1 12.0 3.8 0.17 11.4 2.6 1.3 1 0 0 1 1 1 0 Nucleoplasmin DUF4611 PF15387.1 AEO54255.1 - 0.14 12.3 2.9 0.25 11.5 2.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) RXT2_N PF08595.6 AEO54255.1 - 0.35 10.6 2.9 0.47 10.2 1.5 1.5 2 0 0 2 2 2 0 RXT2-like, N-terminal PBP1_TM PF14812.1 AEO54255.1 - 0.37 11.1 7.2 0.9 9.8 5.0 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RIC1 PF07064.8 AEO54256.1 - 1.2e-89 300.1 0.2 1.8e-89 299.6 0.1 1.2 1 0 0 1 1 1 1 RIC1 WD40 PF00400.27 AEO54256.1 - 3.1e-05 23.6 1.7 0.49 10.3 0.0 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat WD40 PF00400.27 AEO54257.1 - 5.9e-25 86.1 9.1 5.2e-05 22.9 0.0 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 AEO54257.1 - 2.5e-05 22.6 0.1 0.0013 16.9 0.0 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.6 AEO54257.1 - 0.00055 19.7 0.2 2.3 7.9 0.0 3.9 4 1 1 5 5 5 1 Eukaryotic translation initiation factor eIF2A DUF1513 PF07433.6 AEO54257.1 - 0.021 13.7 0.0 0.14 10.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) Nucleoporin_N PF08801.6 AEO54257.1 - 0.042 12.5 0.0 0.083 11.6 0.0 1.6 1 1 0 1 1 1 0 Nup133 N terminal like Cytochrom_D1 PF02239.11 AEO54257.1 - 0.049 11.9 0.0 8.4 4.5 0.0 2.2 1 1 0 2 2 2 0 Cytochrome D1 heme domain DUF3312 PF11768.3 AEO54257.1 - 0.07 11.3 0.0 0.25 9.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) Fungal_trans PF04082.13 AEO54258.1 - 9.4e-22 77.1 0.0 1.8e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO54258.1 - 2.5e-08 33.6 9.1 2.5e-08 33.6 6.3 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 AEO54259.1 - 2.4e-15 56.0 10.4 5.4e-10 38.4 7.6 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter DUF1109 PF06532.6 AEO54259.1 - 0.0061 15.9 0.2 0.0061 15.9 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1109) DUF4131 PF13567.1 AEO54259.1 - 0.87 8.9 6.5 6.7 6.0 1.6 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Trep_Strep PF09605.5 AEO54259.1 - 1.3 8.6 8.4 1.8 8.2 1.2 3.1 2 1 1 3 3 3 0 Hypothetical bacterial integral membrane protein (Trep_Strep) HTH_29 PF13551.1 AEO54260.1 - 3.6e-07 30.3 1.4 6.3e-07 29.5 0.1 2.0 1 1 1 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.1 AEO54260.1 - 2e-06 27.2 1.4 3.5e-05 23.2 0.1 2.5 2 1 0 2 2 2 1 Homeodomain-like domain HTH_24 PF13412.1 AEO54260.1 - 3.5e-06 26.2 0.1 8.9e-05 21.7 0.0 2.6 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.1 AEO54260.1 - 0.00037 19.9 0.9 0.00066 19.1 0.1 1.9 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.13 AEO54260.1 - 0.00099 19.1 3.1 0.13 12.3 0.0 3.1 2 1 1 3 3 3 2 Transposase HTH_11 PF08279.7 AEO54260.1 - 0.0019 17.8 0.4 0.13 11.9 0.0 2.5 2 0 0 2 2 2 1 HTH domain HTH_32 PF13565.1 AEO54260.1 - 0.0021 18.8 0.1 0.0021 18.8 0.1 3.0 2 2 1 3 3 3 1 Homeodomain-like domain Sigma70_r4 PF04545.11 AEO54260.1 - 0.0025 17.0 0.8 0.015 14.6 0.1 2.3 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.7 AEO54260.1 - 0.0081 15.5 0.1 0.079 12.4 0.0 2.4 2 1 0 2 2 2 1 Sigma-70, region 4 MarR PF01047.17 AEO54260.1 - 0.013 15.1 0.2 0.18 11.5 0.0 2.6 3 0 0 3 3 3 0 MarR family HTH_Tnp_ISL3 PF13542.1 AEO54260.1 - 0.016 14.3 0.1 0.056 12.6 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Sigma70_ECF PF07638.6 AEO54260.1 - 0.068 12.8 0.0 0.91 9.1 0.0 2.3 2 0 0 2 2 2 0 ECF sigma factor HTH_DeoR PF08220.7 AEO54260.1 - 0.072 12.6 0.3 0.26 10.8 0.1 2.0 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain HTH_38 PF13936.1 AEO54260.1 - 0.12 11.9 0.0 0.12 11.9 0.0 2.9 4 0 0 4 4 4 0 Helix-turn-helix domain Acetate_kinase PF00871.12 AEO54262.1 - 2e-86 289.9 0.0 3.6e-69 233.1 0.0 2.0 1 1 1 2 2 2 2 Acetokinase family DUF2457 PF10446.4 AEO54262.1 - 1.2 7.7 4.3 1.8 7.2 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) zf-C2H2_4 PF13894.1 AEO54263.1 - 1.3e-05 25.1 8.5 0.00094 19.3 0.2 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 AEO54263.1 - 2e-05 24.6 9.3 0.0059 16.8 0.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 AEO54263.1 - 0.0067 16.6 0.8 0.0067 16.6 0.5 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.2 AEO54263.1 - 0.059 13.5 3.7 7.9 6.8 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type CDK2AP PF09806.4 AEO54263.1 - 0.33 11.1 15.5 1.4 9.1 5.6 2.3 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein zf-C2H2_jaz PF12171.3 AEO54263.1 - 0.89 9.7 3.7 7.9 6.7 0.1 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DUF4614 PF15391.1 AEO54263.1 - 6.9 6.4 18.9 5.5 6.7 2.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) Oxidored_q1 PF00361.15 AEO54264.1 - 7.4e-16 58.2 2.1 7.4e-16 58.2 1.5 2.0 2 0 0 2 2 2 2 NADH-Ubiquinone/plastoquinone (complex I), various chains Prp31_C PF09785.4 AEO54265.1 - 9.3e-43 145.6 0.4 2e-42 144.5 0.3 1.6 1 0 0 1 1 1 1 Prp31 C terminal domain Nop PF01798.13 AEO54265.1 - 4.9e-40 136.2 0.1 8.2e-40 135.5 0.0 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 AEO54265.1 - 2.3e-24 84.9 0.2 4.8e-22 77.4 0.0 2.3 2 0 0 2 2 2 2 NOSIC (NUC001) domain HAT PF02184.11 AEO54266.1 - 3.1e-24 84.4 58.1 4.3e-10 39.1 0.2 12.6 13 0 0 13 13 13 5 HAT (Half-A-TPR) repeat TPR_19 PF14559.1 AEO54266.1 - 1.1e-23 83.2 1.1 3.1e-07 30.6 0.0 7.9 7 1 0 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.1 AEO54266.1 - 5.7e-23 79.3 26.4 1e-05 25.7 0.1 12.2 8 2 6 14 14 13 6 Tetratricopeptide repeat TPR_16 PF13432.1 AEO54266.1 - 3.2e-17 62.7 21.3 0.0048 17.5 0.0 9.1 7 2 3 10 10 9 4 Tetratricopeptide repeat Suf PF05843.9 AEO54266.1 - 1e-15 58.2 12.0 1.1e-05 25.3 0.0 6.8 2 1 4 7 7 7 2 Suppressor of forked protein (Suf) TPR_15 PF13429.1 AEO54266.1 - 5.6e-10 38.7 10.5 0.00018 20.6 2.2 5.5 2 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 AEO54266.1 - 2.5e-08 33.7 13.5 1.1 9.2 0.0 8.5 8 2 2 10 10 10 3 Tetratricopeptide repeat TPR_11 PF13414.1 AEO54266.1 - 1.9e-06 27.4 6.4 0.025 14.2 0.1 6.3 6 2 2 8 8 8 1 TPR repeat TPR_6 PF13174.1 AEO54266.1 - 2.1e-06 27.8 17.8 0.18 12.3 0.0 9.1 10 0 0 10 10 9 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 AEO54266.1 - 1.4e-05 24.8 4.8 0.46 10.3 0.0 5.5 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.1 AEO54266.1 - 0.00029 20.8 13.8 0.26 11.5 0.0 7.2 9 0 0 9 9 7 2 Tetratricopeptide repeat U3_assoc_6 PF08640.6 AEO54266.1 - 0.00045 19.9 16.1 0.032 13.9 1.6 5.7 3 2 3 6 6 6 2 U3 small nucleolar RNA-associated protein 6 YfiO PF13525.1 AEO54266.1 - 0.0019 17.7 0.4 0.011 15.1 0.0 2.5 2 1 0 2 2 2 1 Outer membrane lipoprotein TPR_2 PF07719.12 AEO54266.1 - 0.0024 17.6 22.6 0.0075 16.1 0.1 8.4 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_8 PF13181.1 AEO54266.1 - 0.029 14.1 0.4 35 4.4 0.0 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 AEO54266.1 - 0.033 14.0 2.8 14 5.6 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat NRDE-2 PF08424.5 AEO54266.1 - 0.058 12.2 26.0 0.25 10.1 1.1 5.6 4 2 1 6 6 6 0 NRDE-2, necessary for RNA interference c-SKI_SMAD_bind PF08782.5 AEO54266.1 - 0.16 12.0 2.4 2.9 8.0 0.1 3.6 3 0 0 3 3 3 0 c-SKI Smad4 binding domain TPR_7 PF13176.1 AEO54266.1 - 0.21 11.4 13.5 17 5.5 0.0 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.23 AEO54266.1 - 2.3 7.9 4.9 3.1 7.5 0.0 3.8 5 0 0 5 5 3 0 Tetratricopeptide repeat Corona_nucleoca PF00937.13 AEO54267.1 - 0.0012 17.8 13.0 0.0012 17.8 9.0 5.4 3 1 1 5 5 5 3 Coronavirus nucleocapsid protein HLH PF00010.21 AEO54268.1 - 1.8e-10 40.3 2.2 2.9e-10 39.6 0.0 2.1 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain La PF05383.12 AEO54269.1 - 8e-17 60.7 0.0 1.5e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 La domain Got1 PF04178.7 AEO54270.1 - 3e-29 101.5 15.4 3.9e-29 101.1 10.7 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Peptidase_M50 PF02163.17 AEO54270.1 - 0.062 12.2 0.2 0.14 11.0 0.1 1.7 1 1 0 1 1 1 0 Peptidase family M50 PMP22_Claudin PF00822.15 AEO54270.1 - 0.77 9.3 5.1 0.58 9.7 1.7 1.8 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 AEO54270.1 - 1.2 8.8 11.0 0.39 10.3 1.1 2.2 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction HLH PF00010.21 AEO54271.1 - 3.4e-12 45.8 0.0 1.1e-11 44.2 0.0 1.8 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ribosomal_60s PF00428.14 AEO54271.1 - 0.033 14.5 0.1 0.56 10.6 0.0 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein NPR3 PF03666.8 AEO54272.1 - 4.4e-85 285.9 0.1 4.4e-85 285.9 0.1 1.4 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 DUF605 PF04652.11 AEO54272.1 - 0.052 12.9 11.7 0.081 12.3 8.1 1.2 1 0 0 1 1 1 0 Vta1 like Mito_fiss_reg PF05308.6 AEO54272.1 - 0.12 11.6 10.2 0.28 10.5 7.1 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator Choline_kinase PF01633.15 AEO54273.1 - 3.5e-56 190.1 0.0 3.3e-55 186.9 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 AEO54273.1 - 4e-14 52.9 0.5 2.1e-13 50.5 0.4 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 AEO54273.1 - 0.028 13.5 0.0 0.12 11.5 0.0 1.9 1 1 0 1 1 1 0 Ecdysteroid kinase DUF1679 PF07914.6 AEO54273.1 - 0.034 12.7 0.0 0.045 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) GCV_T PF01571.16 AEO54274.1 - 2.2e-63 213.4 0.0 2.8e-63 213.1 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 AEO54274.1 - 4.3e-23 81.1 0.6 7.8e-23 80.3 0.4 1.4 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SR-25 PF10500.4 AEO54274.1 - 0.076 12.4 7.3 0.11 11.9 5.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein WD40 PF00400.27 AEO54275.1 - 2.5e-26 90.5 7.3 1e-06 28.3 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 AEO54275.1 - 0.0046 15.1 0.6 0.0046 15.1 0.4 2.2 2 2 0 2 2 2 1 Nucleoporin Nup120/160 Hep_59 PF07052.6 AEO54277.1 - 1.1e-20 73.9 2.2 1.1e-20 73.9 1.5 2.5 3 1 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 A_deaminase_N PF08451.6 AEO54277.1 - 0.41 10.7 4.3 0.64 10.0 0.2 2.5 2 0 0 2 2 2 0 Adenosine/AMP deaminase N-terminal Herpes_gE PF02480.11 AEO54279.1 - 0.008 14.4 0.0 0.011 14.0 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E SKG6 PF08693.5 AEO54279.1 - 0.0086 15.3 3.6 0.019 14.3 2.5 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Rax2 PF12768.2 AEO54279.1 - 0.078 12.1 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Lamp PF01299.12 AEO54279.1 - 0.11 11.6 1.0 0.2 10.7 0.7 1.4 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) Mid2 PF04478.7 AEO54279.1 - 0.18 11.2 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF846 PF05832.7 AEO54280.1 - 3.7e-53 179.0 9.5 4.3e-53 178.8 6.6 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) YwiC PF14256.1 AEO54280.1 - 0.039 14.0 8.0 0.24 11.5 0.5 2.1 2 0 0 2 2 2 0 YwiC-like protein DUF4191 PF13829.1 AEO54280.1 - 2.7 7.0 9.0 5.7 5.9 1.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4191) HXXEE PF13787.1 AEO54280.1 - 5 7.5 10.5 0.094 13.0 0.7 2.2 2 1 0 2 2 2 0 Protein of unknown function with HXXEE motif HpcH_HpaI PF03328.9 AEO54281.1 - 1.1e-42 145.4 1.0 1.9e-42 144.6 0.1 1.7 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 AEO54281.1 - 6.4e-14 51.5 0.0 3.4e-06 26.1 0.0 2.2 2 1 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold RRM_1 PF00076.17 AEO54282.1 - 7e-24 83.2 0.1 9.1e-24 82.8 0.1 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO54282.1 - 9.5e-17 60.7 0.0 1.3e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO54282.1 - 8.6e-11 41.5 0.0 1.2e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1877 PF08974.5 AEO54282.1 - 0.1 12.2 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1877) RRM_3 PF08777.6 AEO54282.1 - 0.12 12.1 0.3 0.2 11.5 0.2 1.3 1 1 0 1 1 1 0 RNA binding motif ChaC PF04752.7 AEO54283.1 - 6.1e-57 192.4 0.0 7.7e-57 192.1 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein EF-hand_1 PF00036.27 AEO54284.1 - 1.2e-27 93.0 5.4 1.1e-06 27.5 0.1 5.4 5 0 0 5 5 5 5 EF hand EF-hand_7 PF13499.1 AEO54284.1 - 1.5e-25 89.1 6.1 2.2e-10 40.4 0.5 3.4 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 AEO54284.1 - 3.8e-22 76.1 7.0 5.8e-05 22.6 0.1 5.3 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.1 AEO54284.1 - 1.1e-20 73.0 11.1 6.7e-10 38.4 0.0 5.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 AEO54284.1 - 4.7e-19 66.8 8.0 8.5e-06 24.8 0.2 4.6 4 0 0 4 4 4 4 EF hand EF-hand_10 PF14788.1 AEO54284.1 - 0.091 12.4 0.2 11 5.7 0.0 3.2 2 1 1 3 3 3 0 EF hand EF-hand_9 PF14658.1 AEO54284.1 - 0.093 12.6 0.4 0.83 9.6 0.0 2.7 3 1 0 3 3 3 0 EF-hand domain Rad51 PF08423.6 AEO54288.1 - 2e-27 95.7 0.0 2.2e-27 95.5 0.0 1.0 1 0 0 1 1 1 1 Rad51 Nup160 PF11715.3 AEO54289.1 - 4.1e-158 526.9 0.0 6.4e-158 526.2 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 GvpG PF05120.7 AEO54289.1 - 0.017 14.8 0.0 0.11 12.3 0.0 2.2 2 0 0 2 2 2 0 Gas vesicle protein G TPR_12 PF13424.1 AEO54289.1 - 0.073 13.0 1.0 19 5.3 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Strep_SA_rep PF06696.6 AEO54289.1 - 0.076 12.7 1.0 2.8 7.8 0.1 2.7 2 0 0 2 2 2 0 Streptococcal surface antigen repeat Vps26 PF03643.10 AEO54290.1 - 1.5e-130 433.9 0.5 1.8e-130 433.6 0.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 AEO54290.1 - 0.00021 21.1 0.1 0.16 11.7 0.0 3.4 1 1 2 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Ribosomal_L6 PF00347.18 AEO54291.1 - 1.2e-26 92.9 11.9 9.2e-14 51.7 3.2 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 TMEM51 PF15345.1 AEO54292.1 - 0.011 15.4 1.2 0.038 13.6 0.0 2.1 2 0 0 2 2 2 0 Transmembrane protein 51 DUF1206 PF06724.6 AEO54292.1 - 2 8.2 9.4 1.9 8.3 4.9 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) V-ATPase_H_N PF03224.9 AEO54293.1 - 6.3e-72 242.3 0.0 8.4e-72 241.9 0.0 1.2 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 AEO54293.1 - 6.6e-38 129.2 0.0 1.6e-37 128.0 0.0 1.7 1 0 0 1 1 1 1 V-ATPase subunit H Acylphosphatase PF00708.13 AEO54294.1 - 1.6e-26 92.1 0.2 1.8e-26 92.0 0.1 1.0 1 0 0 1 1 1 1 Acylphosphatase BLUF PF04940.7 AEO54294.1 - 0.024 14.3 0.1 0.036 13.7 0.1 1.3 1 1 0 1 1 1 0 Sensors of blue-light using FAD DUF726 PF05277.7 AEO54295.1 - 1.3e-126 422.1 2.9 1.9e-126 421.6 2.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Fcf1 PF04900.7 AEO54296.1 - 9.5e-22 77.0 0.1 1.8e-21 76.0 0.1 1.5 1 0 0 1 1 1 1 Fcf1 YL1 PF05764.8 AEO54296.1 - 0.087 12.4 14.1 0.14 11.7 9.8 1.3 1 0 0 1 1 1 0 YL1 nuclear protein DUF2763 PF10961.3 AEO54296.1 - 3.3 8.1 12.7 61 4.1 1.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2763) SpoIIE PF07228.7 AEO54297.1 - 5.7e-05 22.8 0.0 0.00029 20.6 0.0 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 AEO54297.1 - 0.0097 15.3 0.0 0.027 13.8 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C PH PF00169.24 AEO54298.1 - 4.7e-06 26.7 0.1 2.6e-05 24.3 0.0 2.3 3 0 0 3 3 3 1 PH domain PH_9 PF15410.1 AEO54298.1 - 0.00082 19.5 0.1 0.0062 16.6 0.0 2.4 3 0 0 3 3 3 1 Pleckstrin homology domain DUF4242 PF14026.1 AEO54298.1 - 0.3 11.1 1.4 0.4 10.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4242) Pkinase PF00069.20 AEO54299.1 - 8.8e-67 224.9 0.0 1.3e-66 224.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO54299.1 - 1.6e-30 106.0 0.0 2.6e-30 105.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 AEO54299.1 - 8.3e-09 35.4 0.1 3.7e-08 33.3 0.0 2.2 2 0 0 2 2 2 1 FHA domain Kinase-like PF14531.1 AEO54299.1 - 8.3e-05 21.6 0.0 0.00032 19.7 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 AEO54299.1 - 0.014 14.5 0.0 0.028 13.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AEO54299.1 - 0.023 14.4 5.7 1.4 8.5 0.1 3.6 3 1 1 4 4 4 0 Phosphotransferase enzyme family STT3 PF02516.9 AEO54301.1 - 2.1e-131 439.2 37.3 8.6e-127 424.0 24.2 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit PMT PF02366.13 AEO54301.1 - 7.2e-05 22.2 12.8 7.2e-05 22.2 8.8 3.1 3 1 1 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Cytomega_TRL10 PF06084.6 AEO54301.1 - 0.51 10.1 2.9 0.29 10.9 0.1 1.9 2 0 0 2 2 2 0 Cytomegalovirus TRL10 protein Ribosomal_L29 PF00831.18 AEO54302.1 - 3.9e-18 64.8 3.2 3.9e-18 64.8 2.2 1.8 2 1 0 2 2 2 1 Ribosomal L29 protein Ribosomal_S9 PF00380.14 AEO54302.1 - 0.001 19.3 0.8 0.0012 19.0 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S9/S16 FlxA PF14282.1 AEO54302.1 - 0.037 13.9 3.2 0.058 13.3 2.2 1.4 1 0 0 1 1 1 0 FlxA-like protein YPEB PF14620.1 AEO54302.1 - 0.16 10.9 2.1 0.2 10.6 1.4 1.1 1 0 0 1 1 1 0 YpeB sporulation DUF2450 PF10475.4 AEO54302.1 - 0.18 10.6 3.3 0.21 10.4 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) M16C_assoc PF08367.6 AEO54302.1 - 0.26 10.0 2.9 0.13 11.1 0.4 1.7 2 0 0 2 2 2 0 Peptidase M16C associated Snapin_Pallidin PF14712.1 AEO54302.1 - 0.5 10.7 7.3 0.095 13.0 2.3 1.7 1 1 1 2 2 2 0 Snapin/Pallidin DUF1241 PF06840.6 AEO54302.1 - 0.68 9.1 4.0 0.79 8.9 1.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1241) ERM PF00769.14 AEO54302.1 - 1.5 8.3 7.2 0.23 10.9 1.7 1.8 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Ribosomal_L6e PF01159.14 AEO54303.1 - 4.4e-37 126.6 0.2 6.2e-37 126.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L6e V-SNARE_C PF12352.3 AEO54304.1 - 1.4e-09 37.8 0.2 1.4e-09 37.8 0.1 2.7 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus FANCI_S4 PF14678.1 AEO54304.1 - 0.044 12.8 0.3 0.07 12.2 0.2 1.3 1 0 0 1 1 1 0 FANCI solenoid 4 ATP-synt_10 PF05176.9 AEO54305.1 - 2.2e-90 302.3 0.0 2.8e-90 302.0 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein 2-oxoacid_dh PF00198.18 AEO54306.1 - 1.7e-75 253.2 0.0 2.5e-75 252.7 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 AEO54306.1 - 1e-17 63.5 0.1 2.3e-17 62.3 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 AEO54306.1 - 3.8e-12 45.6 0.6 8.4e-12 44.5 0.0 2.0 2 0 0 2 2 2 1 e3 binding domain BEX PF04538.7 AEO54306.1 - 0.091 12.9 0.6 0.47 10.7 0.0 2.1 2 0 0 2 2 2 0 Brain expressed X-linked like family SKI PF01202.17 AEO54307.1 - 1.7e-15 57.2 0.0 2.2e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.1 AEO54307.1 - 6.5e-12 45.5 0.0 1e-11 44.8 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AEO54307.1 - 9.8e-12 45.7 0.0 1.2e-11 45.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AEO54307.1 - 1.3e-10 41.7 0.0 2.1e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 AEO54307.1 - 4.4e-05 23.6 0.1 9.9e-05 22.5 0.1 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AEO54307.1 - 9.7e-05 22.5 0.0 0.0002 21.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.10 AEO54307.1 - 0.00016 20.4 0.0 0.00024 19.9 0.0 1.1 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 AEO54307.1 - 0.00019 21.4 0.0 0.0003 20.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 AEO54307.1 - 0.00037 20.1 0.0 0.00079 19.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 AEO54307.1 - 0.0012 19.0 0.0 0.005 16.9 0.0 2.0 2 0 0 2 2 2 1 RNA helicase Cytidylate_kin2 PF13189.1 AEO54307.1 - 0.0014 18.5 0.0 0.03 14.2 0.0 2.3 1 1 0 1 1 1 1 Cytidylate kinase-like family Mg_chelatase PF01078.16 AEO54307.1 - 0.0016 17.6 0.0 0.0024 17.0 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ANF_receptor PF01094.23 AEO54307.1 - 0.0022 16.8 0.0 0.004 16.0 0.0 1.5 1 1 0 1 1 1 1 Receptor family ligand binding region Thymidylate_kin PF02223.12 AEO54307.1 - 0.0023 17.3 0.0 0.12 11.7 0.0 2.2 2 0 0 2 2 2 1 Thymidylate kinase AAA_14 PF13173.1 AEO54307.1 - 0.003 17.4 0.0 0.0066 16.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 AEO54307.1 - 0.0038 16.8 0.0 0.0071 16.0 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Zeta_toxin PF06414.7 AEO54307.1 - 0.0065 15.5 0.0 0.013 14.6 0.0 1.5 1 1 0 1 1 1 1 Zeta toxin ABC_tran PF00005.22 AEO54307.1 - 0.0066 16.7 0.0 0.011 16.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter APS_kinase PF01583.15 AEO54307.1 - 0.0089 15.6 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase CoaE PF01121.15 AEO54307.1 - 0.0093 15.3 0.0 0.056 12.8 0.0 2.0 2 0 0 2 2 2 1 Dephospho-CoA kinase Viral_helicase1 PF01443.13 AEO54307.1 - 0.011 15.2 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.10 AEO54307.1 - 0.015 15.0 0.1 0.14 11.8 0.0 2.1 2 0 0 2 2 2 0 NTPase Arch_ATPase PF01637.13 AEO54307.1 - 0.018 14.7 0.0 0.022 14.4 0.0 1.5 1 1 0 1 1 1 0 Archaeal ATPase AAA_28 PF13521.1 AEO54307.1 - 0.02 14.8 0.0 0.047 13.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 AEO54307.1 - 0.025 14.1 0.0 0.025 14.1 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 AEO54307.1 - 0.032 13.9 0.0 0.059 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) T2SE PF00437.15 AEO54307.1 - 0.033 13.0 0.0 0.063 12.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.1 AEO54307.1 - 0.034 13.6 0.0 0.076 12.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.1 AEO54307.1 - 0.035 13.6 0.0 0.062 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain PRK PF00485.13 AEO54307.1 - 0.037 13.5 0.0 0.079 12.5 0.0 1.6 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family ADK PF00406.17 AEO54307.1 - 0.039 13.8 0.1 1.8 8.3 0.0 2.2 2 0 0 2 2 2 0 Adenylate kinase NB-ARC PF00931.17 AEO54307.1 - 0.045 12.6 0.0 0.072 11.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Sigma54_activat PF00158.21 AEO54307.1 - 0.052 13.0 0.0 0.084 12.3 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 AEO54307.1 - 0.066 13.2 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.1 AEO54307.1 - 0.069 12.5 0.5 0.15 11.4 0.4 1.9 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 AEO54307.1 - 0.098 11.8 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 CobU PF02283.11 AEO54307.1 - 0.11 11.9 0.0 0.29 10.5 0.0 1.7 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase G-alpha PF00503.15 AEO54307.1 - 0.11 11.1 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit MutS_V PF00488.16 AEO54307.1 - 0.11 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 MutS domain V AAA_10 PF12846.2 AEO54307.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain Peptidase_M49 PF03571.10 AEO54308.1 - 3.3e-221 735.1 0.0 3.9e-221 734.9 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 APC_crr PF05923.7 AEO54309.1 - 0.1 12.2 2.0 0.19 11.3 1.4 1.4 1 0 0 1 1 1 0 APC cysteine-rich region zf-C2H2 PF00096.21 AEO54310.1 - 8.9e-25 85.5 30.6 8.6e-06 25.7 0.5 7.4 6 1 0 6 6 6 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 AEO54310.1 - 4.1e-22 77.3 30.0 6.3e-07 29.3 0.0 6.2 7 0 0 7 7 5 5 Zinc-finger double domain zf-C2H2_4 PF13894.1 AEO54310.1 - 7.1e-17 60.4 31.7 0.0024 18.0 0.1 7.3 7 0 0 7 7 6 6 C2H2-type zinc finger zf-C2H2_6 PF13912.1 AEO54310.1 - 7.1e-12 44.7 22.3 0.0037 17.1 0.2 6.0 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 AEO54310.1 - 1.3e-11 44.2 18.3 0.051 13.7 0.0 6.6 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 AEO54310.1 - 1.3e-05 25.2 20.7 0.15 12.2 1.4 5.4 5 1 0 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding zf-RING_3 PF14369.1 AEO54310.1 - 0.00015 21.7 3.1 1.7 8.7 0.1 4.3 3 0 0 3 3 3 2 zinc-finger zf-met PF12874.2 AEO54310.1 - 0.00016 21.7 22.7 0.25 11.5 0.1 6.2 6 1 1 7 7 7 3 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 AEO54310.1 - 0.0012 18.4 11.3 0.75 9.5 0.2 4.8 4 0 0 4 4 4 2 zinc-finger of a C2HC-type NADH-G_4Fe-4S_3 PF10588.4 AEO54310.1 - 0.11 11.7 5.8 1.3 8.3 0.1 3.6 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region zf-C2H2_2 PF12756.2 AEO54310.1 - 0.27 11.3 19.5 0.48 10.5 0.5 5.5 3 1 3 6 6 6 0 C2H2 type zinc-finger (2 copies) DEAD PF00270.24 AEO54312.1 - 2.9e-46 157.0 0.2 3.1e-44 150.4 0.0 2.5 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO54312.1 - 8.5e-24 83.2 0.0 1.5e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 AEO54312.1 - 0.00023 20.0 0.0 0.00038 19.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 AEO54312.1 - 0.00052 19.9 0.0 0.0013 18.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HMG_box PF00505.14 AEO54313.1 - 1.1e-07 31.9 1.9 6.1e-07 29.6 0.4 3.4 4 0 0 4 4 4 2 HMG (high mobility group) box HMG_box_2 PF09011.5 AEO54313.1 - 3.7e-07 30.4 6.7 0.00059 20.1 0.1 3.0 3 1 0 3 3 3 2 HMG-box domain KRAB PF01352.22 AEO54313.1 - 0.16 11.4 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 KRAB box DUF3106 PF11304.3 AEO54313.1 - 0.52 10.7 5.0 3.5 8.0 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3106) Med3 PF11593.3 AEO54313.1 - 1.2 8.2 7.0 1.5 7.9 4.8 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal 3Beta_HSD PF01073.14 AEO54315.1 - 8.8e-69 231.3 0.0 1.1e-68 231.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 AEO54315.1 - 1e-33 116.7 0.3 1.6e-33 116.1 0.0 1.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 AEO54315.1 - 2.2e-17 62.8 0.7 1.2e-14 53.8 0.5 2.1 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 AEO54315.1 - 8.6e-15 54.3 0.1 1.2e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 AEO54315.1 - 3.5e-13 49.9 0.0 4.9e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 AEO54315.1 - 3.1e-08 32.8 0.3 2.6e-07 29.8 0.3 2.3 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 AEO54315.1 - 5.9e-08 32.8 0.5 1.8e-07 31.2 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 AEO54315.1 - 2.8e-06 27.1 0.3 8.8e-06 25.5 0.2 1.8 1 1 0 1 1 1 1 KR domain NmrA PF05368.8 AEO54315.1 - 0.00017 20.9 0.1 0.00032 20.0 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.13 AEO54315.1 - 0.0018 18.2 0.0 0.0031 17.4 0.0 1.5 1 1 0 1 1 1 1 TrkA-N domain Saccharop_dh PF03435.13 AEO54315.1 - 0.012 14.5 0.1 0.054 12.4 0.0 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase DapB_N PF01113.15 AEO54315.1 - 0.022 14.6 0.1 0.07 13.0 0.0 1.9 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_3 PF03447.11 AEO54315.1 - 0.031 14.6 0.0 0.064 13.6 0.0 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain GHL6 PF14871.1 AEO54315.1 - 0.12 12.4 0.0 0.26 11.2 0.0 1.6 1 1 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 RhoGAP PF00620.22 AEO54316.1 - 1.3e-37 128.7 0.1 3.3e-37 127.4 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 AEO54316.1 - 1.3e-29 102.0 38.1 1e-11 44.6 3.7 4.9 5 0 0 5 5 5 4 LIM domain Desulfoferrod_N PF06397.7 AEO54316.1 - 0.1 12.0 1.2 0.52 9.7 0.1 2.7 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain DUF2417 PF10329.4 AEO54317.1 - 1.9e-82 276.1 4.1 2.4e-82 275.8 2.9 1.1 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 AEO54317.1 - 6.3e-06 26.2 0.8 6.3e-06 26.2 0.5 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family E1-E2_ATPase PF00122.15 AEO54317.1 - 9.2 5.2 9.3 11 5.0 2.7 2.2 2 0 0 2 2 2 0 E1-E2 ATPase DUF2890 PF11081.3 AEO54318.1 - 0.46 10.5 3.7 0.68 9.9 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Nop14 PF04147.7 AEO54318.1 - 0.61 7.9 2.6 0.73 7.6 1.8 1.0 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.7 AEO54318.1 - 1.4 7.1 9.0 2.1 6.6 6.2 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) UQ_con PF00179.21 AEO54319.1 - 5.1e-42 142.6 0.0 9e-31 106.1 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme RWD PF05773.17 AEO54319.1 - 0.006 16.4 0.0 0.46 10.3 0.0 2.5 1 1 0 2 2 2 2 RWD domain UEV PF05743.8 AEO54319.1 - 0.06 13.0 0.0 0.21 11.3 0.0 1.8 2 0 0 2 2 2 0 UEV domain AAA PF00004.24 AEO54320.1 - 9.9e-17 61.3 0.1 2.1e-15 57.1 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 AEO54320.1 - 3.4e-13 49.5 0.0 1.1e-07 31.7 0.0 2.4 2 0 0 2 2 2 2 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 AEO54320.1 - 5.4e-12 45.5 0.0 3e-11 43.1 0.0 2.0 2 0 0 2 2 2 1 Replication factor C C-terminal domain Rad17 PF03215.10 AEO54320.1 - 3.7e-11 42.4 0.0 1e-08 34.3 0.0 2.3 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 AEO54320.1 - 2.9e-08 33.8 0.1 0.00032 20.8 0.0 3.4 2 2 0 2 2 2 1 AAA domain RuvB_N PF05496.7 AEO54320.1 - 9.6e-07 28.0 0.0 2.4e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 AEO54320.1 - 1.1e-05 25.0 0.0 3.5e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 AEO54320.1 - 2.2e-05 24.5 0.1 0.00096 19.1 0.0 2.9 2 2 0 3 3 3 1 AAA ATPase domain AAA_11 PF13086.1 AEO54320.1 - 3.6e-05 23.4 0.0 7e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 AEO54320.1 - 0.0001 21.5 0.0 0.0053 15.9 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 AEO54320.1 - 0.00011 22.0 0.0 0.00025 20.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain TMP_2 PF06791.8 AEO54320.1 - 0.00061 19.4 1.0 0.0012 18.4 0.7 1.6 1 0 0 1 1 1 1 Prophage tail length tape measure protein DUF815 PF05673.8 AEO54320.1 - 0.0015 17.5 0.0 0.0024 16.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) DNA_pol3_delta PF06144.8 AEO54320.1 - 0.002 17.6 0.0 0.0041 16.6 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_17 PF13207.1 AEO54320.1 - 0.0027 18.5 0.0 0.01 16.6 0.0 2.0 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 AEO54320.1 - 0.0028 17.4 0.4 0.086 12.5 0.1 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 AEO54320.1 - 0.0035 16.9 0.4 0.0089 15.6 0.2 1.8 1 1 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 AEO54320.1 - 0.0037 16.7 0.1 0.032 13.6 0.0 2.3 2 1 0 2 2 2 1 FtsK/SpoIIIE family DUF2075 PF09848.4 AEO54320.1 - 0.0041 16.1 0.0 0.0084 15.1 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 AEO54320.1 - 0.0055 16.1 0.4 0.027 13.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 AEO54320.1 - 0.014 15.3 0.0 0.077 12.8 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 AEO54320.1 - 0.016 15.4 0.0 0.048 13.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 AEO54320.1 - 0.023 14.6 0.0 0.052 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 AEO54320.1 - 0.038 12.7 0.0 0.55 8.8 0.0 2.3 2 0 0 2 2 2 0 TIP49 C-terminus ResIII PF04851.10 AEO54320.1 - 0.06 13.1 0.0 0.23 11.2 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_10 PF12846.2 AEO54320.1 - 0.07 12.5 0.3 1.4 8.2 0.0 2.6 2 1 0 3 3 3 0 AAA-like domain AAA_3 PF07726.6 AEO54320.1 - 0.078 12.5 0.0 0.45 10.1 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 AEO54320.1 - 0.089 12.4 0.0 0.27 10.9 0.0 1.9 2 1 0 2 2 2 0 Archaeal ATPase RNA_helicase PF00910.17 AEO54320.1 - 0.099 12.8 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Spc97_Spc98 PF04130.8 AEO54320.1 - 0.1 10.9 0.0 2.7 6.2 0.0 2.0 2 0 0 2 2 2 0 Spc97 / Spc98 family SNF2_N PF00176.18 AEO54320.1 - 0.12 11.1 0.0 2.6 6.7 0.0 2.2 2 0 0 2 2 2 0 SNF2 family N-terminal domain KMP11 PF03037.11 AEO54321.1 - 0.37 11.4 3.2 3.2 8.3 0.6 2.8 1 1 1 2 2 2 0 Kinetoplastid membrane protein 11 Sec63 PF02889.11 AEO54322.1 - 1.2e-196 652.1 0.1 5.2e-110 367.5 0.0 2.7 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 AEO54322.1 - 9.5e-56 187.9 0.3 5.6e-30 104.0 0.0 3.7 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.10 AEO54322.1 - 3.6e-20 72.5 0.0 1.3e-08 34.9 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 AEO54322.1 - 1.7e-12 46.9 0.0 2.9e-10 39.8 0.0 3.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 AEO54322.1 - 1.7e-07 31.4 0.1 0.01 16.0 0.0 3.4 2 1 0 2 2 2 2 AAA domain T2SE PF00437.15 AEO54322.1 - 1.3e-05 24.2 0.0 0.084 11.7 0.0 2.8 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_19 PF13245.1 AEO54322.1 - 0.00044 19.9 0.0 0.059 13.1 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_10 PF12846.2 AEO54322.1 - 0.00045 19.7 1.0 2.4 7.5 0.0 4.6 6 1 1 7 7 7 2 AAA-like domain PhoH PF02562.11 AEO54322.1 - 0.0025 17.0 0.0 0.82 8.8 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein UvrD-helicase PF00580.16 AEO54322.1 - 0.0057 16.0 0.0 1.2 8.3 0.0 2.9 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain FtsK_SpoIIIE PF01580.13 AEO54322.1 - 0.016 14.7 0.0 7.4 5.9 0.0 3.1 3 0 0 3 3 3 0 FtsK/SpoIIIE family DUF3335 PF11814.3 AEO54322.1 - 0.038 13.1 0.3 2.8 7.0 0.0 3.1 3 0 0 3 3 3 0 Peptidase_C39 like family PWWP PF00855.12 AEO54323.1 - 7.8e-12 45.2 0.0 7.8e-12 45.2 0.0 2.6 3 0 0 3 3 3 1 PWWP domain ORC3_N PF07034.6 AEO54324.1 - 2.1e-35 122.2 0.4 2.1e-35 122.2 0.3 2.1 2 1 0 2 2 2 1 Origin recognition complex (ORC) subunit 3 N-terminus DUF904 PF06005.7 AEO54324.1 - 0.0064 16.7 0.2 0.024 14.9 0.1 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF904) Atrophin-1 PF03154.10 AEO54325.1 - 0.2 9.7 2.3 0.24 9.5 1.6 1.1 1 0 0 1 1 1 0 Atrophin-1 family Sec66 PF09802.4 AEO54326.1 - 7.3e-82 273.3 0.2 8.3e-82 273.1 0.2 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 NPL4 PF05021.10 AEO54327.1 - 8e-130 432.4 0.0 1e-129 432.1 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 AEO54327.1 - 4.7e-72 240.4 0.1 7.6e-72 239.7 0.1 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 AEO54327.1 - 0.0013 18.9 0.0 0.004 17.3 0.0 1.9 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 DUF4451 PF14616.1 AEO54327.1 - 0.056 13.1 0.3 0.12 12.1 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4451) CPSase_L_D2 PF02786.12 AEO54328.1 - 4.1e-111 369.3 0.1 1.5e-84 282.5 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 AEO54328.1 - 7.6e-42 141.9 0.1 2e-41 140.5 0.1 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 AEO54328.1 - 3e-39 134.6 0.1 1.1e-21 77.3 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain CPSase_L_chain PF00289.17 AEO54328.1 - 9.8e-36 122.2 0.0 2.5e-17 62.9 0.0 2.8 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 AEO54328.1 - 2.2e-26 92.3 0.0 2.5e-09 36.3 0.0 3.7 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 AEO54328.1 - 8.6e-24 83.8 0.1 1.8e-11 43.7 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 AEO54328.1 - 2.6e-20 72.6 1.5 7.8e-11 41.7 0.2 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 AEO54328.1 - 4.7e-09 35.9 0.0 8.9e-06 25.3 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 AEO54328.1 - 1.1e-07 31.8 0.2 0.014 15.2 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.14 AEO54328.1 - 1.8e-07 30.9 0.3 0.0098 15.4 0.1 2.7 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.1 AEO54328.1 - 7.5e-05 22.0 0.1 0.067 12.4 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain MGS PF02142.17 AEO54328.1 - 0.093 12.6 0.0 0.35 10.8 0.0 2.0 1 0 0 1 1 1 0 MGS-like domain Epimerase PF01370.16 AEO54328.1 - 0.11 11.8 0.0 1.7 8.0 0.0 2.3 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF1746 PF08508.5 AEO54329.1 - 9.6e-41 138.3 0.9 1.3e-40 137.9 0.7 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) RTC PF01137.16 AEO54330.1 - 2.1e-32 111.7 0.1 3.1e-32 111.1 0.1 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 AEO54330.1 - 3.7e-31 107.2 0.1 7.6e-31 106.1 0.1 1.6 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain PPR_2 PF13041.1 AEO54331.1 - 3.1e-13 49.4 0.0 4.3e-08 33.0 0.0 5.8 7 0 0 7 7 7 1 PPR repeat family PPR_3 PF13812.1 AEO54331.1 - 2.5e-05 24.1 8.0 0.15 12.3 0.0 6.6 7 0 0 7 7 7 2 Pentatricopeptide repeat domain PPR PF01535.15 AEO54331.1 - 0.008 16.0 0.0 0.008 16.0 0.0 5.2 7 0 0 7 7 7 1 PPR repeat TPR_7 PF13176.1 AEO54331.1 - 0.0086 15.8 2.0 1.6 8.6 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat PPR_1 PF12854.2 AEO54331.1 - 0.02 14.3 0.7 0.66 9.5 0.0 3.5 3 0 0 3 3 3 0 PPR repeat TPR_16 PF13432.1 AEO54331.1 - 0.026 15.1 0.1 13 6.5 0.1 3.5 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 AEO54331.1 - 0.17 12.4 0.8 68 4.2 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 AEO54331.1 - 0.19 12.4 6.4 6.5 7.6 0.0 5.7 5 1 1 6 6 6 0 Tetratricopeptide repeat DUF4187 PF13821.1 AEO54332.1 - 7e-18 63.9 2.5 7e-18 63.9 1.7 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) G-patch PF01585.18 AEO54332.1 - 4.4e-05 23.1 10.6 0.00058 19.5 2.7 2.6 2 0 0 2 2 2 2 G-patch domain Sporozoite_P67 PF05642.6 AEO54332.1 - 3.5 5.3 9.8 3.7 5.2 6.2 1.4 1 1 0 1 1 1 0 Sporozoite P67 surface antigen zf-CCHC PF00098.18 AEO54333.1 - 0.063 13.2 0.2 0.12 12.3 0.2 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2 PF00096.21 AEO54335.1 - 3.1e-10 39.7 21.9 9.7e-07 28.7 0.4 3.1 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 AEO54335.1 - 3e-08 33.5 12.0 2.2e-07 30.7 2.9 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 AEO54335.1 - 1.8e-07 30.9 18.1 0.00072 19.7 4.3 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 AEO54335.1 - 0.0002 21.4 6.7 0.0049 16.9 1.3 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 AEO54335.1 - 0.00052 19.8 8.9 0.0068 16.2 0.2 2.9 2 1 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 AEO54335.1 - 0.00092 19.3 0.4 0.00092 19.3 0.3 2.8 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-BED PF02892.10 AEO54335.1 - 5.9 6.7 7.7 8.8 6.1 1.3 2.4 1 1 1 2 2 2 0 BED zinc finger zf-CCHC PF00098.18 AEO54337.1 - 6.8e-08 32.0 4.5 1.1e-07 31.4 3.1 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 AEO54337.1 - 0.0027 17.3 1.5 0.0057 16.3 1.1 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 AEO54337.1 - 0.077 12.6 3.2 0.14 11.8 2.2 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.1 AEO54337.1 - 0.12 11.8 3.6 0.23 10.9 2.5 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger DUF1876 PF08962.6 AEO54338.1 - 0.052 13.3 0.4 4.4 7.1 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1876) FlgN PF05130.7 AEO54338.1 - 0.079 13.1 2.7 0.13 12.4 1.9 1.4 1 0 0 1 1 1 0 FlgN protein LacI PF00356.16 AEO54338.1 - 0.12 11.9 0.3 6.4 6.4 0.1 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family CCDC-167 PF15188.1 AEO54338.1 - 0.68 9.9 4.0 1.1 9.2 1.2 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 ATP_bind_4 PF01902.12 AEO54339.1 - 7.2e-20 71.2 0.0 3.7e-14 52.6 0.0 4.0 3 1 0 3 3 3 3 ATP-binding region Ribonuc_L-PSP PF01042.16 AEO54339.1 - 2.8e-10 40.0 0.0 1.6e-05 24.6 0.0 3.9 4 0 0 4 4 4 2 Endoribonuclease L-PSP Cwf_Cwc_15 PF04889.7 AEO54339.1 - 1.1 8.9 4.0 47 3.5 0.0 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.7 AEO54339.1 - 5 4.9 4.6 12 3.6 3.5 1.3 2 0 0 2 2 2 0 Nop14-like family COesterase PF00135.23 AEO54340.1 - 1.6e-82 277.9 0.0 3.9e-81 273.3 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 AEO54340.1 - 0.00028 20.6 0.0 0.00044 20.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 AEO54340.1 - 0.00034 20.2 1.1 0.00094 18.8 0.8 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold SR-25 PF10500.4 AEO54340.1 - 1.7 8.0 7.8 2.5 7.5 5.4 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DAGAT PF03982.8 AEO54341.1 - 1.1e-91 306.5 0.0 1.5e-91 306.1 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Rer1 PF03248.8 AEO54341.1 - 0.046 13.3 0.1 0.068 12.7 0.0 1.2 1 0 0 1 1 1 0 Rer1 family zf-H2C2_2 PF13465.1 AEO54342.1 - 7e-15 54.4 19.5 1e-08 34.9 1.4 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 AEO54342.1 - 2e-10 40.3 24.0 0.0038 17.4 4.9 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AEO54342.1 - 2.6e-07 30.4 21.4 0.0078 16.4 4.1 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 AEO54342.1 - 0.0045 17.0 10.7 0.7 10.1 2.3 3.6 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 AEO54342.1 - 0.055 13.5 12.0 0.2 11.8 4.6 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 AEO54342.1 - 0.095 12.6 11.2 0.83 9.6 0.0 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger DZR PF12773.2 AEO54342.1 - 0.26 11.1 7.0 6.2 6.7 4.8 2.3 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_3 PF14369.1 AEO54342.1 - 0.3 11.0 8.0 11 6.0 0.1 3.3 2 1 1 3 3 3 0 zinc-finger Macoilin PF09726.4 AEO54342.1 - 0.34 9.1 10.0 0.0076 14.5 1.7 1.8 2 0 0 2 2 2 0 Transmembrane protein DUF2225 PF09986.4 AEO54342.1 - 0.35 10.3 3.0 1 8.7 0.8 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) PyrI_C PF02748.10 AEO54342.1 - 0.47 9.9 2.3 0.44 10.0 0.6 1.7 1 1 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C3HC4_3 PF13920.1 AEO54342.1 - 0.75 9.5 4.8 8.7 6.1 0.6 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn-ribbon_8 PF09723.5 AEO54342.1 - 1 9.3 9.7 5.8 6.9 2.3 3.0 1 1 2 3 3 3 0 Zinc ribbon domain zf-CHY PF05495.7 AEO54342.1 - 1.2 9.3 8.1 2.6 8.2 5.6 1.5 1 0 0 1 1 1 0 CHY zinc finger GAGA PF09237.6 AEO54342.1 - 1.3 8.6 6.8 1.6 8.4 0.5 2.9 1 1 2 3 3 3 0 GAGA factor Rad50_zn_hook PF04423.9 AEO54342.1 - 1.6 8.2 6.2 1.2 8.6 0.3 2.7 3 0 0 3 3 2 0 Rad50 zinc hook motif zf-C2H2_2 PF12756.2 AEO54342.1 - 3.9 7.6 11.7 1.9 8.6 1.5 3.1 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_4 PF13717.1 AEO54342.1 - 6 6.6 6.1 43 3.9 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain FYDLN_acid PF09538.5 AEO54342.1 - 6.1 7.4 10.1 58 4.3 0.6 3.9 2 1 1 3 3 3 0 Protein of unknown function (FYDLN_acid) zinc_ribbon_5 PF13719.1 AEO54342.1 - 7.5 6.2 6.5 38 3.9 0.2 3.1 3 0 0 3 3 3 0 zinc-ribbon domain zf-CHCC PF10276.4 AEO54342.1 - 7.5 6.4 13.2 1.2 9.0 0.2 3.2 4 0 0 4 4 3 0 Zinc-finger domain zf-C2HC_2 PF13913.1 AEO54342.1 - 8.2 6.2 7.4 0.42 10.3 0.3 2.2 2 0 0 2 2 2 0 zinc-finger of a C2HC-type SUN PF03856.8 AEO54343.1 - 1.2e-83 280.2 11.3 1.5e-83 279.9 7.8 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) BNR PF02012.15 AEO54344.1 - 1.8e-13 48.0 34.9 0.41 10.6 0.0 11.4 11 0 0 11 11 11 7 BNR/Asp-box repeat DUF3825 PF12873.2 AEO54344.1 - 0.059 12.5 0.1 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3825) LAM_C PF12544.3 AEO54346.1 - 3.4e-05 23.8 0.0 8.9e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Lysine-2,3-aminomutase Radical_SAM PF04055.16 AEO54346.1 - 0.0015 18.7 0.0 0.0081 16.3 0.0 2.2 2 1 0 2 2 2 1 Radical SAM superfamily MFS_1 PF07690.11 AEO54347.1 - 3.1e-29 101.7 53.2 5.5e-19 68.0 15.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 AEO54347.1 - 0.0036 15.4 1.7 0.0036 15.4 1.2 1.6 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family DUF677 PF05055.7 AEO54347.1 - 0.2 10.3 3.9 0.36 9.4 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF677) SHS2_Rpb7-N PF03876.12 AEO54348.1 - 3.1e-15 56.0 0.0 4.8e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 AEO54348.1 - 6.5e-08 32.5 0.0 1e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.7 AEO54348.1 - 0.082 13.1 0.0 0.22 11.6 0.0 1.7 1 1 1 2 2 2 0 RNA polymerase III subunit Rpc25 DUF962 PF06127.6 AEO54349.1 - 3.2e-26 91.0 1.7 4.4e-26 90.6 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF962) Apq12 PF12716.2 AEO54350.1 - 2.9e-06 26.8 8.6 5.7e-06 25.9 5.9 1.5 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis ATP_bind_1 PF03029.12 AEO54351.1 - 1.3e-72 244.1 0.1 1.7e-72 243.8 0.1 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 AEO54351.1 - 1.9e-05 25.4 0.0 5.3e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 AEO54351.1 - 0.00026 20.9 0.0 0.00072 19.4 0.0 1.9 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 AEO54351.1 - 0.00029 20.9 0.0 0.00066 19.8 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.1 AEO54351.1 - 0.00049 20.2 0.0 0.0013 18.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 AEO54351.1 - 0.001 18.8 0.0 0.0021 17.7 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 AEO54351.1 - 0.0065 16.3 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 AEO54351.1 - 0.01 15.7 0.0 0.03 14.2 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.1 AEO54351.1 - 0.012 15.1 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 AEO54351.1 - 0.014 14.8 0.1 0.051 13.0 0.0 1.9 2 1 0 2 2 2 0 AAA-like domain AAA_31 PF13614.1 AEO54351.1 - 0.023 14.6 0.0 0.11 12.4 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 AEO54351.1 - 0.027 14.4 0.0 0.056 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 AEO54351.1 - 0.028 13.9 0.0 0.057 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRP54 PF00448.17 AEO54351.1 - 0.028 13.8 0.0 0.053 12.9 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ArsA_ATPase PF02374.10 AEO54351.1 - 0.031 13.3 0.0 0.059 12.3 0.0 1.4 1 0 0 1 1 1 0 Anion-transporting ATPase NACHT PF05729.7 AEO54351.1 - 0.032 13.8 0.0 0.065 12.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.1 AEO54351.1 - 0.035 14.4 0.0 0.1 12.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 AEO54351.1 - 0.035 13.1 0.0 0.062 12.3 0.0 1.4 1 0 0 1 1 1 0 Septin IstB_IS21 PF01695.12 AEO54351.1 - 0.041 13.3 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein PPV_E1_C PF00519.12 AEO54351.1 - 0.045 12.3 0.0 0.081 11.5 0.0 1.3 1 0 0 1 1 1 0 Papillomavirus helicase DUF258 PF03193.11 AEO54351.1 - 0.047 12.8 0.0 0.08 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 AEO54351.1 - 0.053 12.9 0.0 0.13 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 AEO54351.1 - 0.053 13.2 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Hpr_kinase_C PF07475.7 AEO54351.1 - 0.058 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain CbiA PF01656.18 AEO54351.1 - 0.064 12.6 0.0 0.14 11.5 0.0 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain TRADD_N PF09034.5 AEO54351.1 - 0.075 13.0 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 TRADD, N-terminal domain AAA PF00004.24 AEO54351.1 - 0.077 13.1 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 AEO54351.1 - 0.15 11.4 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain S-AdoMet_synt_C PF02773.11 AEO54352.1 - 1.3e-76 254.9 0.2 2.1e-76 254.2 0.1 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 AEO54352.1 - 7.9e-47 158.1 0.0 1.4e-46 157.3 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 AEO54352.1 - 1.9e-41 140.3 0.3 3.7e-41 139.3 0.0 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain FlxA PF14282.1 AEO54353.1 - 0.11 12.4 3.7 0.47 10.4 2.6 2.1 1 0 0 1 1 1 0 FlxA-like protein THF_DHG_CYH PF00763.18 AEO54354.1 - 2.3e-20 72.7 0.1 3.4e-20 72.2 0.1 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 AEO54354.1 - 8.4e-14 50.9 0.0 1.7e-08 33.7 0.0 2.6 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SBP_bac_5 PF00496.17 AEO54354.1 - 0.018 13.8 0.1 0.026 13.3 0.1 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle MMS19_N PF14500.1 AEO54355.1 - 1.8e-41 142.1 0.0 5e-41 140.7 0.0 1.8 1 0 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 AEO54355.1 - 1.7e-11 43.5 0.0 1.4e-08 33.9 0.0 3.8 3 2 0 3 3 3 2 RNAPII transcription regulator C-terminal SPC25 PF06703.6 AEO54356.1 - 5.6e-54 182.0 0.0 7e-54 181.7 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF106 PF01956.11 AEO54357.1 - 3.9e-56 189.1 1.1 5.3e-56 188.7 0.7 1.2 1 0 0 1 1 1 1 Integral membrane protein DUF106 WBP-1 PF11669.3 AEO54357.1 - 0.15 12.1 0.0 1.4 8.9 0.0 2.2 2 0 0 2 2 2 0 WW domain-binding protein 1 NUFIP1 PF10453.4 AEO54358.1 - 2.1e-13 49.5 1.5 8.3e-13 47.6 1.1 2.1 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.19 AEO54358.1 - 0.0019 17.8 5.3 0.004 16.7 3.7 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Macoilin PF09726.4 AEO54358.1 - 0.11 10.7 3.2 0.18 10.0 2.3 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF4463 PF14703.1 AEO54358.1 - 0.16 12.5 5.5 0.29 11.6 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4463) DUF4574 PF15141.1 AEO54360.1 - 0.0063 16.2 0.1 0.014 15.1 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4574) HA PF03457.9 AEO54360.1 - 0.055 13.5 0.1 0.2 11.7 0.0 2.2 1 1 0 1 1 1 0 Helicase associated domain SET PF00856.23 AEO54361.1 - 6.9e-12 45.9 0.0 5.8e-07 29.9 0.0 2.5 1 1 1 2 2 2 2 SET domain Ribosomal_S19 PF00203.16 AEO54362.1 - 2.9e-35 119.7 0.4 4.4e-35 119.1 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 Glyco_hydro_53 PF07745.8 AEO54363.1 - 4.4e-124 413.6 1.9 4.9e-124 413.4 1.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 DUF4015 PF13200.1 AEO54363.1 - 0.034 13.0 0.1 0.052 12.4 0.1 1.3 1 0 0 1 1 1 0 Putative glycosyl hydrolase domain ADH_N PF08240.7 AEO54364.1 - 3.3e-06 26.8 0.1 6.8e-06 25.8 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AEO54364.1 - 1.2e-05 24.8 0.1 3.1e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glutaredoxin PF00462.19 AEO54365.1 - 3.5e-13 49.3 0.0 8e-13 48.1 0.0 1.7 1 0 0 1 1 1 1 Glutaredoxin AAA_11 PF13086.1 AEO54366.1 - 1.4 8.4 7.4 2.7 7.4 5.1 1.5 1 0 0 1 1 1 0 AAA domain PA26 PF04636.8 AEO54366.1 - 2 7.0 5.9 2.9 6.4 4.1 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Ribosomal_L21p PF00829.16 AEO54367.1 - 0.00036 20.5 0.0 0.00069 19.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein PAT1 PF09770.4 AEO54367.1 - 0.49 8.5 9.9 0.56 8.3 6.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Suf PF05843.9 AEO54367.1 - 0.86 9.2 5.9 1.2 8.7 4.1 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Pkinase PF00069.20 AEO54368.1 - 7.8e-46 156.3 0.0 1.1e-45 155.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO54368.1 - 2e-20 72.9 0.0 3.6e-20 72.1 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO54368.1 - 0.00057 18.9 0.1 0.0065 15.4 0.0 2.4 2 1 0 2 2 2 1 Kinase-like APH PF01636.18 AEO54368.1 - 0.0016 18.1 0.1 0.22 11.2 0.0 2.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 AEO54368.1 - 0.067 12.5 0.1 0.2 10.9 0.0 1.7 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.9 AEO54368.1 - 0.12 11.4 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PsaA_PsaB PF00223.14 AEO54368.1 - 0.49 8.4 0.0 0.7 7.9 0.0 1.1 1 0 0 1 1 1 0 Photosystem I psaA/psaB protein Ribosomal_60s PF00428.14 AEO54369.1 - 1.2e-28 99.2 12.9 1.5e-28 99.0 8.9 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3824 PF12868.2 AEO54369.1 - 6.1 7.7 8.6 8.6 7.3 6.0 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) SPT2 PF08243.6 AEO54370.1 - 3.3e-05 24.1 25.8 3.3e-05 24.1 17.9 2.6 2 1 0 2 2 2 1 SPT2 chromatin protein Ribosomal_S8e PF01201.17 AEO54371.1 - 3.4e-36 124.2 9.3 6.9e-36 123.3 6.4 1.5 1 1 0 1 1 1 1 Ribosomal protein S8e DUF2390 PF09523.5 AEO54371.1 - 5.9 7.1 6.6 12 6.0 4.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2390) IBR PF01485.16 AEO54372.1 - 1.4e-06 28.0 1.5 1.4e-06 28.0 1.0 2.5 2 1 0 2 2 2 1 IBR domain zf-RING_5 PF14634.1 AEO54372.1 - 0.00049 19.7 1.4 0.00049 19.7 1.0 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 AEO54372.1 - 0.0006 19.5 1.5 0.0006 19.5 1.1 2.6 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 AEO54372.1 - 0.0017 17.9 0.6 0.0017 17.9 0.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AEO54372.1 - 0.011 15.7 1.6 0.011 15.7 1.1 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Tim17 PF02466.14 AEO54373.1 - 3.5e-29 101.4 0.1 5.3e-29 100.8 0.1 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Zn_clus PF00172.13 AEO54374.1 - 5.3e-11 42.2 10.9 9.5e-11 41.4 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 AEO54374.1 - 4.3e-08 32.3 0.4 6.9e-08 31.6 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Adeno_terminal PF02459.10 AEO54374.1 - 0.19 9.8 0.8 0.34 9.0 0.6 1.3 1 0 0 1 1 1 0 Adenoviral DNA terminal protein MGC-24 PF05283.6 AEO54374.1 - 0.46 10.2 11.6 0.9 9.2 8.0 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) FAD_binding_3 PF01494.14 AEO54375.1 - 1.5e-22 80.1 0.0 2.3e-22 79.5 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 AEO54375.1 - 3.6e-10 39.2 1.2 0.00018 20.5 0.3 2.1 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 AEO54375.1 - 1.9e-05 24.9 0.2 0.00049 20.4 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 AEO54375.1 - 0.00022 20.1 0.0 0.0017 17.2 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 AEO54375.1 - 0.0019 18.1 0.1 0.0047 16.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.11 AEO54375.1 - 0.011 15.1 0.1 0.019 14.4 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.9 AEO54375.1 - 0.057 13.2 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AEO54376.1 - 2.8e-17 63.4 0.0 4.2e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 AEO54376.1 - 0.00072 19.4 0.0 0.0089 15.9 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 AEO54376.1 - 0.003 16.5 0.0 0.43 9.4 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 AEO54376.1 - 0.0076 16.0 0.2 0.9 9.3 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 AEO54376.1 - 0.13 11.3 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Lipase_GDSL_2 PF13472.1 AEO54377.1 - 1.3e-15 58.0 0.3 1.7e-15 57.5 0.2 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 AEO54377.1 - 5.7e-10 39.4 0.1 3.7e-09 36.7 0.0 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 AEO54377.1 - 0.15 11.8 0.0 0.58 9.8 0.0 1.9 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family RVT_1 PF00078.22 AEO54378.1 - 0.037 13.3 0.1 0.037 13.3 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C2H2 PF00096.21 AEO54379.1 - 0.019 15.3 0.4 0.019 15.3 0.3 4.7 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AEO54379.1 - 0.46 10.9 0.1 0.46 10.9 0.1 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger ApoLp-III PF07464.6 AEO54380.1 - 0.0007 19.6 0.2 0.00093 19.2 0.1 1.3 1 1 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) AIRC PF00731.15 AEO54380.1 - 0.1 11.8 0.1 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 AIR carboxylase Antimicrobial_2 PF08023.7 AEO54380.1 - 0.92 9.8 2.9 48 4.3 2.0 2.9 1 1 0 1 1 1 0 Frog antimicrobial peptide HLH PF00010.21 AEO54382.1 - 6.8e-13 48.1 1.1 1.4e-12 47.0 0.4 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF3106 PF11304.3 AEO54382.1 - 0.19 12.1 5.2 0.72 10.2 0.9 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3106) SlyX PF04102.7 AEO54382.1 - 0.94 9.8 5.8 0.37 11.1 1.0 2.4 2 0 0 2 2 2 0 SlyX RVT_1 PF00078.22 AEO54383.1 - 0.0094 15.3 0.5 0.0096 15.2 0.3 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ycf54 PF10674.4 AEO54383.1 - 0.03 14.4 0.6 0.056 13.5 0.2 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2488) RRM_1 PF00076.17 AEO54384.1 - 7e-35 118.4 0.0 1.3e-16 59.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO54384.1 - 8.8e-29 99.2 0.0 5.1e-15 55.2 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO54384.1 - 2.3e-16 59.3 0.0 3.1e-09 36.5 0.0 2.9 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PCRF PF03462.13 AEO54384.1 - 0.019 14.6 0.6 0.034 13.8 0.4 1.4 1 0 0 1 1 1 0 PCRF domain HSP70 PF00012.15 AEO54384.1 - 0.1 10.4 4.2 0.14 10.0 2.9 1.1 1 0 0 1 1 1 0 Hsp70 protein TPR_1 PF00515.23 AEO54385.1 - 2.4e-24 83.8 5.1 6.9e-08 31.7 0.0 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.1 AEO54385.1 - 4.7e-24 83.8 11.9 5e-10 38.8 0.4 4.3 3 1 1 4 4 4 4 TPR repeat TPR_2 PF07719.12 AEO54385.1 - 7.1e-22 75.5 15.1 9.2e-07 28.3 0.0 6.3 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 AEO54385.1 - 1.1e-18 66.0 11.7 7.5e-06 26.1 0.0 6.8 6 2 2 8 8 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 AEO54385.1 - 6e-17 61.8 14.1 1.1e-06 29.1 1.8 4.5 3 2 1 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 AEO54385.1 - 9.4e-17 59.7 6.3 0.0022 18.0 0.0 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 AEO54385.1 - 1.3e-14 52.7 0.7 0.00011 21.7 0.0 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 AEO54385.1 - 2.4e-14 53.0 5.3 1.5e-07 31.2 0.1 4.4 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.1 AEO54385.1 - 2.3e-13 48.8 4.8 0.005 16.5 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 AEO54385.1 - 4.8e-13 49.2 8.2 0.00052 20.2 4.0 4.8 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_9 PF13371.1 AEO54385.1 - 4.1e-10 39.3 5.9 0.0016 18.2 0.0 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.1 AEO54385.1 - 4.9e-09 36.1 7.3 0.04 14.0 0.0 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.1 AEO54385.1 - 4e-07 30.0 8.6 0.8 10.2 0.0 6.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_15 PF13429.1 AEO54385.1 - 0.00013 21.1 1.3 0.18 10.8 0.3 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 AEO54385.1 - 0.012 15.5 8.8 0.54 10.2 0.1 5.0 5 1 0 5 5 4 0 Tetratricopeptide repeat NatB_MDM20 PF09797.4 AEO54385.1 - 0.042 12.5 0.0 0.08 11.6 0.0 1.4 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit DUF1641 PF07849.6 AEO54385.1 - 0.086 12.4 0.2 0.33 10.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1641) AAA_23 PF13476.1 AEO54385.1 - 0.1 12.9 1.4 0.19 12.0 1.0 1.4 1 0 0 1 1 1 0 AAA domain TPR_3 PF07720.7 AEO54385.1 - 0.16 11.8 1.5 12 5.7 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat IncA PF04156.9 AEO54385.1 - 0.23 11.0 6.5 0.53 9.8 4.5 1.6 1 0 0 1 1 1 0 IncA protein RNase_T PF00929.19 AEO54386.1 - 8.9e-22 78.1 0.0 1.6e-21 77.2 0.0 1.5 1 0 0 1 1 1 1 Exonuclease Yippee-Mis18 PF03226.9 AEO54387.1 - 0.00098 19.1 0.6 0.0042 17.1 0.4 2.0 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly IncA PF04156.9 AEO54387.1 - 0.0078 15.8 0.2 0.016 14.8 0.2 1.5 1 0 0 1 1 1 1 IncA protein THOC7 PF05615.8 AEO54387.1 - 0.029 14.6 0.2 0.12 12.6 0.2 2.0 1 1 1 2 2 2 0 Tho complex subunit 7 ATG16 PF08614.6 AEO54387.1 - 0.28 11.0 2.9 15 5.3 0.0 2.6 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) SlyX PF04102.7 AEO54387.1 - 0.63 10.4 5.6 50 4.3 0.0 4.4 4 1 1 5 5 5 0 SlyX Spectrin PF00435.16 AEO54387.1 - 1.2 9.4 4.8 10 6.4 0.3 3.0 2 1 0 3 3 3 0 Spectrin repeat SET PF00856.23 AEO54388.1 - 2.7e-10 40.7 0.0 1.1e-09 38.7 0.0 2.0 3 0 0 3 3 3 1 SET domain zf-MYND PF01753.13 AEO54388.1 - 3.5e-09 36.3 10.0 3.5e-09 36.3 7.0 1.8 2 0 0 2 2 2 1 MYND finger Prefoldin PF02996.12 AEO54389.1 - 1.6e-25 89.0 0.2 2.3e-25 88.5 0.1 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 AEO54389.1 - 0.0033 17.1 0.7 1.7 8.4 0.0 2.1 2 0 0 2 2 2 2 Prefoldin subunit Cep57_MT_bd PF06657.8 AEO54389.1 - 0.01 15.7 0.1 0.02 14.8 0.1 1.5 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 TMF_TATA_bd PF12325.3 AEO54389.1 - 0.24 11.1 1.4 0.38 10.4 0.1 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF1192 PF06698.6 AEO54389.1 - 0.97 9.2 4.2 0.33 10.7 0.2 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) AAA PF00004.24 AEO54391.1 - 6.7e-14 52.2 0.0 1.2e-13 51.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 AEO54391.1 - 2.8e-10 40.4 0.0 2.6e-09 37.3 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain BAH PF01426.13 AEO54391.1 - 3.3e-08 33.2 0.0 7.4e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 BAH domain AAA_22 PF13401.1 AEO54391.1 - 5.8e-07 29.7 0.0 1.3e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AEO54391.1 - 0.00019 22.2 0.0 0.001 19.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 AEO54391.1 - 0.00043 19.9 0.6 0.0014 18.2 0.4 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 AEO54391.1 - 0.0085 16.0 0.0 0.048 13.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 AEO54391.1 - 0.016 15.5 0.0 0.04 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zot PF05707.7 AEO54391.1 - 0.022 14.2 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) DUF2075 PF09848.4 AEO54391.1 - 0.034 13.1 0.0 0.11 11.5 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 AEO54391.1 - 0.041 13.4 0.9 0.092 12.3 0.0 2.0 2 1 0 2 2 1 0 AAA domain AAA_32 PF13654.1 AEO54391.1 - 0.055 12.1 0.0 0.095 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 AEO54391.1 - 0.086 12.7 1.3 0.62 9.9 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_10 PF12846.2 AEO54391.1 - 0.11 11.9 0.0 6.7 6.0 0.0 2.4 2 1 1 3 3 3 0 AAA-like domain UPF0079 PF02367.12 AEO54391.1 - 0.19 11.3 0.1 0.8 9.3 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Ank_5 PF13857.1 AEO54392.1 - 1.4e-11 44.2 0.1 1.8e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 AEO54392.1 - 5.3e-10 39.4 0.0 6.4e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 AEO54392.1 - 1.5e-08 34.0 1.5 2.4e-06 27.0 0.1 2.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 AEO54392.1 - 5.3e-08 33.1 0.0 1.2e-07 32.0 0.0 1.6 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 AEO54392.1 - 9.3e-07 28.5 0.1 0.00067 19.6 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat TMF_TATA_bd PF12325.3 AEO54393.1 - 2.3e-39 133.8 9.1 2.3e-39 133.8 6.3 5.4 3 2 2 5 5 4 2 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 AEO54393.1 - 5.8e-10 38.8 6.8 5.8e-10 38.8 4.7 8.8 3 3 4 7 7 7 1 TATA element modulatory factor 1 DNA binding Tropomyosin_1 PF12718.2 AEO54393.1 - 0.0006 19.6 18.2 0.0006 19.6 12.6 4.4 3 1 1 4 4 4 2 Tropomyosin like AAA_13 PF13166.1 AEO54393.1 - 0.0045 15.5 10.8 0.0045 15.5 7.5 3.2 2 1 1 3 3 3 1 AAA domain CENP-F_leu_zip PF10473.4 AEO54393.1 - 0.012 15.4 12.9 0.012 15.4 8.9 5.1 2 1 2 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Baculo_PEP_C PF04513.7 AEO54393.1 - 0.013 15.3 16.9 0.12 12.1 3.0 4.3 3 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Filament PF00038.16 AEO54393.1 - 0.1 12.0 67.8 0.39 10.1 2.9 4.8 2 1 3 5 5 5 0 Intermediate filament protein Reo_sigmaC PF04582.7 AEO54393.1 - 0.4 9.8 16.9 0.43 9.7 3.6 3.3 2 1 0 3 3 3 0 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 AEO54393.1 - 0.54 9.9 79.1 0.055 13.2 9.9 5.7 2 2 3 5 5 5 0 TPR/MLP1/MLP2-like protein MbeD_MobD PF04899.7 AEO54393.1 - 0.71 9.8 23.6 0.45 10.4 0.7 4.9 3 1 1 4 4 4 0 MbeD/MobD like IncA PF04156.9 AEO54393.1 - 0.96 9.0 75.8 0.066 12.7 2.9 4.9 2 1 3 5 5 5 0 IncA protein Phage_GP20 PF06810.6 AEO54393.1 - 5.2 6.4 59.9 0.42 10.0 1.3 5.5 3 2 2 5 5 5 0 Phage minor structural protein GP20 Nup188 PF10487.4 AEO54393.1 - 6.3 4.5 8.3 10 3.9 5.8 1.2 1 0 0 1 1 1 0 Nucleoporin subcomplex protein binding to Pom34 ATG16 PF08614.6 AEO54393.1 - 6.5 6.5 64.5 0.38 10.5 2.5 4.5 2 1 1 3 3 2 0 Autophagy protein 16 (ATG16) DUF948 PF06103.6 AEO54393.1 - 9.5 6.1 18.8 1.5 8.6 1.4 5.3 3 2 2 5 5 5 0 Bacterial protein of unknown function (DUF948) Ceramidase PF05875.7 AEO54394.1 - 1.8e-86 289.5 8.5 2.3e-86 289.1 5.9 1.1 1 0 0 1 1 1 1 Ceramidase Prefoldin_2 PF01920.15 AEO54394.1 - 1.5e-20 72.9 0.7 2.3e-20 72.3 0.5 1.3 1 0 0 1 1 1 1 Prefoldin subunit TMF_TATA_bd PF12325.3 AEO54394.1 - 0.016 14.9 2.7 0.17 11.6 0.0 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF16 PF01519.11 AEO54394.1 - 0.092 12.9 1.7 0.21 11.8 1.2 1.6 1 1 0 1 1 1 0 Protein of unknown function DUF16 Matrilin_ccoil PF10393.4 AEO54394.1 - 0.11 11.8 0.0 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin EamA PF00892.15 AEO54394.1 - 0.42 10.6 10.4 0.97 9.4 5.5 2.4 2 1 0 2 2 2 0 EamA-like transporter family PAP2 PF01569.16 AEO54394.1 - 1.3 8.6 8.2 0.43 10.2 3.2 2.0 2 0 0 2 2 2 0 PAP2 superfamily FlxA PF14282.1 AEO54394.1 - 1.9 8.4 9.1 4.1 7.3 2.3 2.1 2 0 0 2 2 2 0 FlxA-like protein Mito_carr PF00153.22 AEO54396.1 - 2.4e-50 168.1 2.0 2e-18 65.8 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Dor1 PF04124.7 AEO54397.1 - 1.3e-66 224.3 5.7 1.1e-62 211.4 2.1 3.8 3 1 0 3 3 3 3 Dor1-like family Latarcin PF10279.4 AEO54397.1 - 0.011 15.9 0.0 0.19 11.9 0.0 2.3 2 1 0 2 2 2 0 Latarcin precursor COG5 PF10392.4 AEO54397.1 - 0.073 13.0 3.4 0.27 11.1 2.4 2.0 1 1 0 1 1 1 0 Golgi transport complex subunit 5 Ribosomal_60s PF00428.14 AEO54397.1 - 1.7 9.0 5.5 8.1 6.9 1.0 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein TRAM_LAG1_CLN8 PF03798.11 AEO54401.1 - 3.4e-51 173.6 9.3 5.1e-51 173.0 6.5 1.3 1 0 0 1 1 1 1 TLC domain SH3_1 PF00018.23 AEO54402.1 - 1.6e-36 123.4 7.6 3.5e-12 45.5 0.0 4.4 4 0 0 4 4 4 4 SH3 domain SHD1 PF03983.7 AEO54402.1 - 5e-36 122.1 0.0 8.6e-36 121.4 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_9 PF14604.1 AEO54402.1 - 9.4e-33 111.5 10.2 8e-13 47.7 0.2 4.5 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.12 AEO54402.1 - 2.6e-21 74.8 0.3 1.5e-07 30.7 0.0 4.4 4 0 0 4 4 4 4 Variant SH3 domain SH3_3 PF08239.6 AEO54402.1 - 4.4e-06 26.7 4.2 0.16 12.2 0.2 3.4 3 0 0 3 3 3 2 Bacterial SH3 domain DUF1720 PF08226.6 AEO54402.1 - 0.0039 17.2 35.0 0.0039 17.2 24.3 6.8 1 1 4 5 5 5 2 Domain of unknown function (DUF1720) A_deaminase PF00962.17 AEO54403.1 - 5.6e-109 364.0 0.1 7.2e-109 363.6 0.1 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase UAA PF08449.6 AEO54404.1 - 1.2e-99 333.0 4.8 1.4e-99 332.8 3.3 1.0 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 AEO54404.1 - 3.9e-05 22.8 0.3 3.9e-05 22.8 0.2 2.0 2 0 0 2 2 2 1 Nucleotide-sugar transporter TPT PF03151.11 AEO54404.1 - 8.8e-05 22.1 0.7 8.8e-05 22.1 0.5 2.5 2 1 1 3 3 3 1 Triose-phosphate Transporter family EmrE PF13536.1 AEO54404.1 - 0.036 14.2 17.6 0.16 12.1 2.2 3.6 2 1 1 3 3 3 0 Multidrug resistance efflux transporter UPF0546 PF10639.4 AEO54404.1 - 0.97 9.2 6.0 5.8 6.7 0.5 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0546 EamA PF00892.15 AEO54404.1 - 1.3 9.0 29.3 0.33 10.9 4.9 3.6 2 1 2 4 4 4 0 EamA-like transporter family VWA_2 PF13519.1 AEO54405.1 - 4e-14 53.0 0.0 6e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 AEO54405.1 - 7.8e-08 32.1 0.0 1.2e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.23 AEO54405.1 - 3.4e-05 23.6 0.2 4.9e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.15 AEO54405.1 - 0.00034 19.9 1.4 0.0013 18.1 1.0 2.0 1 0 0 1 1 1 1 Ubiquitin interaction motif Nbl1_Borealin_N PF10444.4 AEO54406.1 - 2.9e-21 74.5 2.8 4.9e-21 73.8 1.9 1.4 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal SUI1 PF01253.17 AEO54407.1 - 3.7e-23 81.1 0.3 8.7e-23 79.9 0.2 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 TnpV PF14198.1 AEO54407.1 - 0.0014 18.4 0.1 0.0024 17.7 0.1 1.4 1 0 0 1 1 1 1 Transposon-encoded protein TnpV Methyltransf_11 PF08241.7 AEO54409.1 - 1.8e-12 47.5 0.0 4.9e-12 46.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO54409.1 - 0.00031 20.4 0.0 0.00071 19.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AEO54409.1 - 0.012 14.7 0.0 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 AEO54409.1 - 0.023 14.2 0.0 0.047 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 AEO54409.1 - 0.027 14.9 0.0 0.063 13.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 AEO54409.1 - 0.2 12.0 0.0 0.43 10.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain zf-C2H2_4 PF13894.1 AEO54410.1 - 0.00038 20.5 25.0 0.068 13.5 0.0 5.9 6 0 0 6 6 6 3 C2H2-type zinc finger Lar_restr_allev PF14354.1 AEO54410.1 - 0.063 13.5 1.0 14 6.0 0.3 2.9 2 0 0 2 2 2 0 Restriction alleviation protein Lar zf-C2H2_6 PF13912.1 AEO54410.1 - 0.15 12.0 0.6 1.6 8.7 0.5 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 AEO54410.1 - 4.8 7.7 26.6 3.3 8.2 0.0 6.2 6 0 0 6 6 6 0 Zinc finger, C2H2 type DUF4281 PF14108.1 AEO54411.1 - 0.045 13.8 0.4 0.082 13.0 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4281) SR-25 PF10500.4 AEO54411.1 - 5.1 6.4 19.8 1.6 8.1 8.5 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Metallophos PF00149.23 AEO54412.1 - 1.3e-07 31.1 2.9 3.3e-07 29.8 2.0 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Nop14 PF04147.7 AEO54412.1 - 0.00016 19.7 14.4 0.00016 19.7 10.0 2.0 2 0 0 2 2 2 1 Nop14-like family YL1 PF05764.8 AEO54412.1 - 0.0037 16.9 28.5 0.021 14.4 14.5 2.3 2 0 0 2 2 2 2 YL1 nuclear protein SDA1 PF05285.7 AEO54412.1 - 0.0045 16.3 15.0 0.0045 16.3 10.4 2.4 2 1 0 2 2 2 1 SDA1 NST1 PF13945.1 AEO54412.1 - 0.52 10.3 17.5 0.45 10.5 0.5 2.3 2 0 0 2 2 2 0 Salt tolerance down-regulator Daxx PF03344.10 AEO54412.1 - 2 6.7 20.6 0.049 12.1 9.5 1.7 2 0 0 2 2 2 0 Daxx Family Cwf_Cwc_15 PF04889.7 AEO54412.1 - 5.8 6.5 27.7 0.27 10.8 12.4 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Polysacc_deac_1 PF01522.16 AEO54413.1 - 9.4e-25 86.6 0.0 1.7e-24 85.7 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Cys_Met_Meta_PP PF01053.15 AEO54415.1 - 1e-58 198.4 0.0 2.3e-58 197.3 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Ofd1_CTDD PF10637.4 AEO54417.1 - 2e-103 345.1 0.1 1.9e-95 319.0 0.3 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 AEO54417.1 - 9e-15 55.0 0.0 2.4e-14 53.6 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 AEO54417.1 - 0.076 12.6 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Aminotran_5 PF00266.14 AEO54418.1 - 9.4e-53 179.2 0.0 9.5e-47 159.5 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 AEO54418.1 - 0.00015 20.2 0.0 0.00022 19.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Ribul_P_3_epim PF00834.14 AEO54419.1 - 2e-64 216.4 0.0 4.5e-63 212.0 0.0 2.0 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family ThiG PF05690.9 AEO54419.1 - 0.008 15.2 0.2 0.012 14.7 0.1 1.2 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG OMPdecase PF00215.19 AEO54419.1 - 0.017 14.4 0.1 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family QRPTase_C PF01729.14 AEO54419.1 - 0.097 12.1 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain DUF4243 PF14027.1 AEO54420.1 - 3.1e-87 293.1 0.5 3.7e-87 292.8 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) zf-C2H2_4 PF13894.1 AEO54422.1 - 3.1e-05 23.9 3.1 0.028 14.7 0.0 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 AEO54422.1 - 0.00036 20.7 4.8 0.28 11.6 0.4 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 AEO54422.1 - 0.00057 20.0 1.1 0.0027 17.9 0.0 2.3 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_2 PF12756.2 AEO54422.1 - 0.086 12.9 0.6 0.14 12.2 0.4 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 AEO54422.1 - 0.092 12.5 0.7 0.22 11.3 0.5 1.7 1 0 0 1 1 1 0 BED zinc finger zf-Di19 PF05605.7 AEO54422.1 - 0.11 12.6 0.2 0.22 11.6 0.1 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 AEO54422.1 - 0.11 12.3 2.4 14 5.7 0.2 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger Cullin PF00888.17 AEO54423.1 - 1.2e-45 156.1 0.0 1.9e-45 155.5 0.0 1.2 1 0 0 1 1 1 1 Cullin family APC2 PF08672.6 AEO54423.1 - 1.4e-20 73.3 0.1 2.8e-20 72.3 0.1 1.6 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 FeoC PF09012.5 AEO54423.1 - 0.00056 19.5 0.0 0.0014 18.3 0.0 1.6 1 0 0 1 1 1 1 FeoC like transcriptional regulator zf-RING_2 PF13639.1 AEO54424.1 - 1.1e-12 47.5 3.6 2.3e-12 46.5 2.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 AEO54424.1 - 7.7e-12 45.1 0.6 1.6e-11 44.1 0.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 AEO54424.1 - 7.2e-07 28.9 0.4 1.5e-06 27.9 0.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 AEO54424.1 - 7.4e-07 29.1 3.9 1.3e-06 28.3 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO54424.1 - 1.4e-05 24.6 2.8 2.4e-05 23.9 1.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 AEO54424.1 - 5e-05 22.8 3.0 8.5e-05 22.1 2.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AEO54424.1 - 0.00014 21.4 1.7 0.00024 20.7 1.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 AEO54424.1 - 0.00036 20.1 1.6 0.00093 18.8 1.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger FANCL_C PF11793.3 AEO54424.1 - 0.0053 16.6 4.5 0.09 12.7 3.1 2.4 1 1 0 1 1 1 1 FANCL C-terminal domain Baculo_RING PF05883.6 AEO54424.1 - 0.0065 16.3 0.3 0.012 15.4 0.2 1.3 1 0 0 1 1 1 1 Baculovirus U-box/Ring-like domain zf-Nse PF11789.3 AEO54424.1 - 0.069 12.6 0.7 0.19 11.2 0.5 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 AEO54424.1 - 1 9.2 3.8 2.7 7.9 2.6 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING APH PF01636.18 AEO54425.1 - 3.6e-46 157.8 0.1 3.6e-46 157.8 0.1 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 AEO54425.1 - 1.5e-05 24.3 0.0 2.2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 AEO54425.1 - 0.0015 18.1 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 AEO54425.1 - 0.0016 17.5 0.0 0.0084 15.1 0.0 2.1 1 1 0 1 1 1 1 Fructosamine kinase RIO1 PF01163.17 AEO54425.1 - 0.003 16.9 0.0 0.36 10.1 0.0 2.2 2 0 0 2 2 2 2 RIO1 family DUF1679 PF07914.6 AEO54425.1 - 0.045 12.3 0.0 0.98 7.9 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1679) Rad17 PF03215.10 AEO54426.1 - 1.8e-52 178.7 0.0 3.8e-52 177.6 0.0 1.4 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 AEO54426.1 - 0.00072 19.2 0.0 0.0031 17.2 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 AEO54426.1 - 0.0015 18.5 0.0 0.0039 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 AEO54426.1 - 0.0021 18.2 0.0 0.0051 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 AEO54426.1 - 0.0099 15.5 0.0 0.023 14.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain T2SE PF00437.15 AEO54426.1 - 0.011 14.6 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.24 AEO54426.1 - 0.013 15.6 0.0 0.027 14.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 AEO54426.1 - 0.031 15.1 0.0 0.083 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 AEO54426.1 - 0.04 12.9 0.0 0.08 12.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.22 AEO54426.1 - 0.064 13.5 0.0 0.25 11.6 0.0 1.9 2 0 0 2 2 2 0 ABC transporter AAA_5 PF07728.9 AEO54426.1 - 0.07 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 AEO54426.1 - 0.072 12.9 0.0 0.24 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 AEO54426.1 - 0.073 13.3 0.0 0.21 11.8 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.1 AEO54426.1 - 0.23 11.3 0.0 0.5 10.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain ORC6 PF05460.8 AEO54426.1 - 2.3 7.2 7.0 4.1 6.4 4.8 1.5 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Pkr1 PF08636.5 AEO54427.1 - 3.7e-36 123.0 3.7 5e-36 122.6 2.6 1.2 1 0 0 1 1 1 1 ER protein Pkr1 OAD_gamma PF04277.8 AEO54427.1 - 0.13 12.6 1.0 1.2 9.5 0.7 2.3 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain LSM PF01423.17 AEO54428.1 - 3.3e-15 55.3 0.0 4.3e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 AEO54428.1 - 0.0003 20.6 0.0 0.00043 20.1 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF3247 PF11607.3 AEO54428.1 - 0.14 12.3 0.0 0.2 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3247) API5 PF05918.6 AEO54428.1 - 0.64 8.4 8.9 0.76 8.2 6.2 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Methyltransf_26 PF13659.1 AEO54429.1 - 4.1e-19 68.7 0.7 5.8e-19 68.2 0.5 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AEO54429.1 - 0.00097 18.5 0.0 0.0018 17.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Sporozoite_P67 PF05642.6 AEO54431.1 - 0.01 13.7 2.4 0.019 12.8 1.6 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PKD_channel PF08016.7 AEO54431.1 - 0.12 10.8 8.1 1.6 7.0 0.2 2.2 2 0 0 2 2 2 0 Polycystin cation channel Mito_fiss_reg PF05308.6 AEO54431.1 - 0.21 10.9 8.7 0.37 10.1 6.0 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Mt_ATP-synt_B PF05405.9 AEO54432.1 - 2.2e-53 180.0 11.9 2.7e-53 179.7 8.2 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Orthopox_A5L PF06193.6 AEO54432.1 - 0.0058 16.5 0.7 0.0058 16.5 0.5 1.8 1 1 1 2 2 2 1 Orthopoxvirus A5L protein-like DUF1539 PF07560.6 AEO54432.1 - 0.055 13.3 1.3 0.11 12.3 0.4 1.7 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1539) UPF0052 PF01933.13 AEO54432.1 - 0.1 11.8 1.0 0.14 11.4 0.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0052 TetR PF13972.1 AEO54432.1 - 0.19 11.1 3.4 0.3 10.5 1.8 1.7 1 1 1 2 2 2 0 Bacterial transcriptional repressor AAA_23 PF13476.1 AEO54432.1 - 0.24 11.6 1.6 0.3 11.4 1.1 1.2 1 0 0 1 1 1 0 AAA domain Rep_trans PF02486.14 AEO54432.1 - 0.74 9.2 4.7 0.38 10.2 1.1 1.8 1 1 1 2 2 2 0 Replication initiation factor DUF724 PF05266.9 AEO54432.1 - 4.2 6.9 11.2 5.7 6.5 6.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF724) CBF PF03914.12 AEO54433.1 - 7.1e-45 152.3 0.0 1.6e-44 151.2 0.0 1.6 1 0 0 1 1 1 1 CBF/Mak21 family bZIP_1 PF00170.16 AEO54435.1 - 2.6e-08 33.7 21.2 3.3e-07 30.1 9.9 2.5 2 0 0 2 2 2 2 bZIP transcription factor bZIP_Maf PF03131.12 AEO54435.1 - 2.8e-06 27.5 13.8 2.8e-06 27.5 9.6 2.1 2 0 0 2 2 2 1 bZIP Maf transcription factor bZIP_2 PF07716.10 AEO54435.1 - 3.1e-06 26.8 12.4 3.1e-06 26.8 8.6 2.7 1 1 1 2 2 2 1 Basic region leucine zipper Endotoxin_N PF03945.9 AEO54435.1 - 0.068 12.5 5.7 0.14 11.5 4.0 1.4 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain Med6 PF04934.9 AEO54435.1 - 0.084 12.4 0.1 0.084 12.4 0.0 2.0 2 0 0 2 2 2 0 MED6 mediator sub complex component DUF724 PF05266.9 AEO54435.1 - 0.22 11.1 14.6 0.47 10.0 10.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Adenine_glyco PF03352.8 AEO54435.1 - 0.27 10.7 6.4 0.24 10.9 3.3 1.8 2 0 0 2 2 2 0 Methyladenine glycosylase V_ATPase_I PF01496.14 AEO54435.1 - 1.7 6.3 8.3 2.5 5.8 5.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF342 PF03961.8 AEO54435.1 - 2.4 6.4 14.3 3.9 5.7 9.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF1664 PF07889.7 AEO54435.1 - 5.1 6.9 12.4 2.5 7.8 6.4 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Sel1 PF08238.7 AEO54436.1 - 1.6e-20 73.0 3.5 5.5e-07 30.0 0.0 3.5 3 0 0 3 3 3 3 Sel1 repeat DUF566 PF04484.7 AEO54436.1 - 7.2 6.0 14.2 10 5.5 9.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) WD40 PF00400.27 AEO54438.1 - 9.7e-66 215.4 19.1 3.6e-08 32.9 0.1 12.2 12 0 0 12 12 12 9 WD domain, G-beta repeat Utp12 PF04003.7 AEO54438.1 - 9.4e-22 77.0 0.1 2.9e-21 75.4 0.1 1.8 2 0 0 2 2 2 1 Dip2/Utp12 Family Nucleoporin_N PF08801.6 AEO54438.1 - 6.8e-05 21.7 3.0 0.65 8.6 0.1 5.7 2 2 1 6 6 6 1 Nup133 N terminal like Nup160 PF11715.3 AEO54438.1 - 0.0021 16.2 3.2 0.04 12.0 0.1 3.9 4 2 1 5 5 5 1 Nucleoporin Nup120/160 DUF3312 PF11768.3 AEO54438.1 - 0.023 12.9 0.0 0.22 9.6 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3312) eIF2A PF08662.6 AEO54438.1 - 0.059 13.0 0.0 2.4 7.8 0.0 3.5 3 1 1 4 4 4 0 Eukaryotic translation initiation factor eIF2A P34-Arc PF04045.9 AEO54439.1 - 9.8e-101 336.0 0.1 1.2e-100 335.8 0.1 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Pyr_redox_3 PF13738.1 AEO54440.1 - 1.8e-26 93.4 0.0 3.9e-26 92.3 0.0 1.6 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 AEO54440.1 - 8.2e-16 57.2 0.0 6.6e-15 54.3 0.0 2.1 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 AEO54440.1 - 2.2e-12 46.5 0.0 1.1e-07 31.1 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 AEO54440.1 - 1.1e-08 34.9 0.0 2.9e-08 33.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 AEO54440.1 - 1.3e-05 25.0 0.5 4e-05 23.4 0.0 2.1 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 AEO54440.1 - 0.00029 20.7 0.0 0.0016 18.3 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 AEO54440.1 - 0.0017 17.4 0.0 0.0036 16.4 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 AEO54440.1 - 0.013 14.3 0.0 0.022 13.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 AEO54440.1 - 0.014 13.8 0.1 0.022 13.2 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Sporozoite_P67 PF05642.6 AEO54440.1 - 0.035 11.9 0.1 0.044 11.6 0.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen LBR_tudor PF09465.5 AEO54440.1 - 0.051 13.2 0.1 0.19 11.3 0.1 2.0 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain DUF3446 PF11928.3 AEO54440.1 - 0.054 13.7 5.1 0.13 12.4 3.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) GIDA PF01134.17 AEO54440.1 - 0.2 10.4 0.0 0.36 9.6 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A zf-CCCH PF00642.19 AEO54441.1 - 9.3e-09 34.7 24.1 0.003 17.1 0.0 6.3 6 0 0 6 6 6 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) TFIIF_beta PF02270.10 AEO54442.1 - 1.9e-75 254.1 2.8 2.4e-75 253.8 1.9 1.0 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit Slx4 PF09494.5 AEO54442.1 - 0.059 13.1 0.2 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Slx4 endonuclease HAD PF12710.2 AEO54443.1 - 5.2e-16 59.3 0.0 9.3e-16 58.5 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 AEO54443.1 - 0.0045 16.3 0.4 0.02 14.1 0.0 2.0 2 0 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.7 AEO54443.1 - 0.009 15.6 0.1 0.03 13.8 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Inos-1-P_synth PF01658.12 AEO54443.1 - 0.089 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase Put_Phosphatase PF06888.7 AEO54443.1 - 0.12 11.5 0.5 8.1 5.5 0.0 2.5 2 1 0 2 2 2 0 Putative Phosphatase SNase PF00565.12 AEO54444.1 - 1.7e-22 79.7 0.0 3.2e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Rax2 PF12768.2 AEO54445.1 - 4.7e-88 295.0 2.7 2.7e-79 266.2 0.0 4.2 4 0 0 4 4 4 2 Cortical protein marker for cell polarity Kelch_6 PF13964.1 AEO54445.1 - 2.6e-05 24.2 10.4 3.8 7.8 0.0 7.2 7 0 0 7 7 7 2 Kelch motif Kelch_1 PF01344.20 AEO54445.1 - 0.00039 19.8 0.1 0.15 11.6 0.0 3.6 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 AEO54445.1 - 0.0094 15.7 0.3 0.0094 15.7 0.2 5.9 6 0 0 6 6 6 1 Galactose oxidase, central domain Kelch_3 PF13415.1 AEO54445.1 - 0.032 14.4 17.2 0.22 11.7 0.1 5.9 6 0 0 6 6 6 0 Galactose oxidase, central domain Kelch_2 PF07646.10 AEO54445.1 - 0.057 13.2 3.0 1.1 9.1 0.1 4.0 4 0 0 4 4 4 0 Kelch motif Reg_prop PF07494.6 AEO54445.1 - 0.55 10.4 3.9 16 5.9 0.0 5.1 6 0 0 6 6 6 0 Two component regulator propeller zf-H2C2_2 PF13465.1 AEO54446.1 - 9.1e-11 41.5 11.0 4e-05 23.6 0.1 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 AEO54446.1 - 4.2e-10 39.3 10.0 2.1e-05 24.5 3.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AEO54446.1 - 1.7e-07 31.0 7.1 0.00022 21.3 1.6 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 AEO54446.1 - 6.8e-06 26.0 1.5 2.1e-05 24.5 1.0 1.9 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 AEO54446.1 - 6.9e-06 25.7 6.2 0.0044 16.8 1.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 AEO54446.1 - 3.6e-05 23.7 4.0 0.00013 21.9 1.4 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 AEO54446.1 - 0.054 13.6 0.3 0.054 13.6 0.2 1.6 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) PAP2 PF01569.16 AEO54446.1 - 0.067 12.8 0.9 0.12 11.9 0.0 1.9 2 0 0 2 2 2 0 PAP2 superfamily zf-BED PF02892.10 AEO54446.1 - 0.81 9.5 3.7 0.59 9.9 0.3 2.1 2 0 0 2 2 2 0 BED zinc finger TFIIA PF03153.8 AEO54446.1 - 3.2 7.5 4.7 4.9 6.9 3.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SF3b1 PF08920.5 AEO54447.1 - 1e-37 129.4 2.2 2.3e-37 128.2 0.0 2.3 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 AEO54447.1 - 1.4e-16 60.5 1.3 0.01 16.1 0.0 7.7 6 3 2 8 8 8 6 HEAT repeats HEAT PF02985.17 AEO54447.1 - 1.8e-11 43.1 8.1 0.51 10.5 0.0 9.5 10 0 0 10 10 10 2 HEAT repeat HEAT_EZ PF13513.1 AEO54447.1 - 3.3e-11 43.3 0.9 0.33 11.5 0.0 7.4 6 1 1 7 7 7 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 AEO54447.1 - 8e-06 26.1 0.2 1.1 9.7 0.0 5.2 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 AEO54447.1 - 3.3e-05 22.4 0.3 0.0086 14.4 0.0 3.2 2 2 1 3 3 3 2 Adaptin N terminal region UPF0236 PF06782.6 AEO54447.1 - 0.00067 18.1 0.0 0.0013 17.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0236) CLASP_N PF12348.3 AEO54447.1 - 0.013 14.8 0.1 1.3 8.3 0.0 3.3 3 0 0 3 3 3 0 CLASP N terminal NUC173 PF08161.7 AEO54447.1 - 0.017 14.4 0.1 16 4.7 0.0 3.9 4 0 0 4 4 4 0 NUC173 domain Cnd1 PF12717.2 AEO54447.1 - 0.038 13.8 0.1 62 3.3 0.0 4.4 5 1 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 HECT_2 PF09814.4 AEO54448.1 - 3.3e-62 210.2 0.0 4.2e-62 209.9 0.0 1.1 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding HhH-GPD PF00730.20 AEO54449.1 - 2.3e-16 59.9 0.0 6.8e-16 58.4 0.0 1.7 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein OGG_N PF07934.7 AEO54449.1 - 5.2e-16 58.6 0.0 9.5e-16 57.8 0.0 1.4 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HHH PF00633.18 AEO54449.1 - 7.9e-05 22.1 0.0 0.00019 20.9 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif RRM_1 PF00076.17 AEO54450.1 - 5e-30 102.9 0.1 2.2e-13 49.6 0.0 3.8 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO54450.1 - 1.6e-21 76.0 0.0 1.1e-07 31.7 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO54450.1 - 5.7e-15 54.9 0.1 1e-05 25.2 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Smg4_UPF3 PF03467.10 AEO54450.1 - 0.18 11.7 0.0 9.3 6.2 0.0 2.3 2 0 0 2 2 2 0 Smg-4/UPF3 family Nup35_RRM_2 PF14605.1 AEO54450.1 - 0.18 11.6 0.0 7.6 6.3 0.0 2.8 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Ribosomal_S13_N PF08069.7 AEO54451.1 - 1.3e-30 105.0 0.1 2.5e-30 104.0 0.1 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 AEO54451.1 - 2.7e-23 81.5 0.0 4.8e-23 80.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 AEO54451.1 - 0.014 15.0 0.1 0.035 13.8 0.0 1.7 2 0 0 2 2 2 0 'Paired box' domain Dpy-30 PF05186.8 AEO54452.1 - 9.7e-05 21.7 0.0 0.00015 21.1 0.0 1.3 1 0 0 1 1 1 1 Dpy-30 motif Dicty_REP PF05086.7 AEO54452.1 - 2 6.0 10.8 2.5 5.7 7.5 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF605 PF04652.11 AEO54452.1 - 4.7 6.5 33.9 5.2 6.3 23.5 1.1 1 0 0 1 1 1 0 Vta1 like Suf PF05843.9 AEO54452.1 - 8.6 5.9 7.1 9.5 5.8 4.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.4 AEO54452.1 - 8.8 4.4 29.2 9 4.3 20.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 VRR_NUC PF08774.6 AEO54454.1 - 7.9e-18 64.3 0.0 2e-17 63.0 0.0 1.7 1 0 0 1 1 1 1 VRR-NUC domain DUF4597 PF15366.1 AEO54454.1 - 0.12 12.0 0.0 0.39 10.3 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4597) Ycf1 PF05758.7 AEO54455.1 - 0.05 11.3 0.5 0.047 11.4 0.4 1.0 1 0 0 1 1 1 0 Ycf1 Tim54 PF11711.3 AEO54455.1 - 0.087 11.4 6.7 0.13 10.7 4.7 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CDC45 PF02724.9 AEO54455.1 - 0.19 9.7 3.6 0.2 9.6 2.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DDHD PF02862.12 AEO54455.1 - 0.31 10.8 8.1 0.45 10.2 5.6 1.2 1 0 0 1 1 1 0 DDHD domain SAPS PF04499.10 AEO54455.1 - 1.1 7.8 4.3 1.3 7.5 3.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Vfa1 PF08432.5 AEO54455.1 - 4.2 7.3 16.3 6.7 6.7 11.3 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF605 PF04652.11 AEO54455.1 - 9.2 5.5 26.0 15 4.8 18.0 1.3 1 1 0 1 1 1 0 Vta1 like CBFB_NFYA PF02045.10 AEO54457.1 - 4.2e-30 104.0 4.3 1e-29 102.8 3.0 1.7 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B CytochromB561_N PF09786.4 AEO54457.1 - 0.16 10.3 10.2 0.21 10.0 7.0 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Hus1 PF04005.7 AEO54457.1 - 0.19 10.6 0.2 0.34 9.8 0.0 1.4 1 1 0 1 1 1 0 Hus1-like protein Shadoo PF14999.1 AEO54457.1 - 3.9 7.3 8.3 18 5.1 2.7 2.4 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective LSM PF01423.17 AEO54458.1 - 1.2e-15 56.7 1.1 1.6e-15 56.3 0.7 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 AEO54458.1 - 0.0019 18.0 0.0 0.0025 17.6 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Gemin7 PF11095.3 AEO54458.1 - 0.04 13.6 0.0 0.073 12.8 0.0 1.4 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) HTH_25 PF13413.1 AEO54458.1 - 0.058 13.0 0.0 0.15 11.7 0.0 1.6 1 1 1 2 2 2 0 Helix-turn-helix domain DRMBL PF07522.9 AEO54459.1 - 3.4e-29 101.0 0.0 6.8e-29 100.1 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 AEO54459.1 - 2.6e-12 46.7 0.0 5.7e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 AEO54459.1 - 0.0018 17.9 0.1 0.004 16.8 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF2052 PF09747.4 AEO54459.1 - 0.0038 17.1 0.7 0.0067 16.3 0.5 1.3 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Peptidase_M57 PF12388.3 AEO54459.1 - 0.025 13.9 0.0 0.048 12.9 0.0 1.4 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase DUF1644 PF07800.7 AEO54459.1 - 0.046 13.5 2.4 0.55 10.0 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1644) PDEase_II PF02112.10 AEO54459.1 - 0.22 10.4 0.0 7.8 5.3 0.0 2.1 2 0 0 2 2 2 0 cAMP phosphodiesterases class-II eIF-3_zeta PF05091.7 AEO54460.1 - 2.9e-202 672.9 0.0 3.5e-202 672.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF569 PF04601.8 AEO54460.1 - 0.0014 18.1 0.1 0.0033 16.8 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF569) bZIP_1 PF00170.16 AEO54461.1 - 0.00066 19.5 8.0 0.0014 18.5 5.5 1.5 1 0 0 1 1 1 1 bZIP transcription factor PAP1 PF08601.5 AEO54461.1 - 0.0052 16.5 0.0 0.15 11.7 0.0 2.4 2 0 0 2 2 2 1 Transcription factor PAP1 TSC22 PF01166.13 AEO54461.1 - 0.093 12.7 0.7 0.24 11.3 0.5 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family bZIP_Maf PF03131.12 AEO54461.1 - 0.78 10.0 7.3 1.7 9.0 5.0 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF904 PF06005.7 AEO54461.1 - 1.5 9.1 6.8 0.2 11.9 1.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF904) TMEM51 PF15345.1 AEO54461.1 - 3.6 7.1 6.5 0.27 10.9 1.0 1.6 2 0 0 2 2 2 0 Transmembrane protein 51 RVT_1 PF00078.22 AEO54462.1 - 0.00044 19.6 0.2 0.00044 19.6 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.20 AEO54463.1 - 2.7e-63 213.5 0.0 2.1e-39 135.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AEO54463.1 - 2.4e-27 95.6 0.0 2.4e-20 72.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 AEO54463.1 - 8.6e-12 45.0 0.0 1.9e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 AEO54463.1 - 1.6e-07 30.6 0.0 2.4e-05 23.4 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 AEO54463.1 - 4.5e-06 26.5 0.0 0.0034 17.1 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family PAS PF00989.19 AEO54463.1 - 0.00026 20.7 0.1 0.0037 17.0 0.0 2.4 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 AEO54463.1 - 0.00069 19.9 0.0 0.0018 18.5 0.0 1.7 1 0 0 1 1 1 1 PAS domain Pkinase_C PF00433.19 AEO54463.1 - 0.0083 16.6 0.5 0.13 12.8 0.0 3.4 2 0 0 2 2 2 1 Protein kinase C terminal domain Kdo PF06293.9 AEO54463.1 - 0.028 13.4 0.0 0.048 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 AEO54463.1 - 0.13 11.0 0.1 0.22 10.3 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Sugar_tr PF00083.19 AEO54464.1 - 2.6e-22 79.0 25.3 3.6e-12 45.5 7.6 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter Zn_clus PF00172.13 AEO54465.1 - 3e-09 36.6 13.9 5.2e-09 35.8 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 AEO54465.1 - 2.6e-08 33.0 0.9 1.7e-07 30.3 0.6 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain SNF2_N PF00176.18 AEO54466.1 - 3.2e-29 101.6 0.0 9.4e-28 96.8 0.0 2.1 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 AEO54466.1 - 6e-05 22.8 0.0 0.00012 21.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain LRR_4 PF12799.2 AEO54471.1 - 0.0051 16.3 2.7 3 7.5 0.3 3.5 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AEO54471.1 - 0.014 15.1 1.3 0.1 12.3 0.2 2.5 2 0 0 2 2 2 0 Leucine rich repeat LRR_6 PF13516.1 AEO54471.1 - 0.13 12.3 0.3 8.3 6.8 0.0 2.9 1 1 1 2 2 2 0 Leucine Rich repeat HSCB_C PF07743.8 AEO54472.1 - 7.4e-18 64.7 1.8 7.4e-18 64.7 1.3 1.6 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 AEO54472.1 - 0.00011 21.8 3.9 0.00011 21.8 0.4 2.4 2 1 0 2 2 2 1 DnaJ domain Secretin_N_2 PF07655.8 AEO54472.1 - 0.11 12.8 6.9 0.24 11.8 4.8 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain CDK2AP PF09806.4 AEO54472.1 - 0.18 11.9 4.0 0.052 13.7 0.5 1.8 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein PCI PF01399.22 AEO54473.1 - 8.9e-12 45.2 0.0 1e-10 41.8 0.0 2.6 3 0 0 3 3 3 1 PCI domain RPN7 PF10602.4 AEO54473.1 - 8.4e-05 22.0 0.2 0.00023 20.5 0.2 1.7 1 1 1 2 2 2 1 26S proteasome subunit RPN7 Lipase_GDSL_2 PF13472.1 AEO54474.1 - 1.7e-22 80.4 0.0 2e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 AEO54474.1 - 2.9e-07 30.5 0.0 1.1e-05 25.4 0.0 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase FMN_dh PF01070.13 AEO54475.1 - 2.6e-105 352.2 0.0 3.3e-105 351.8 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 AEO54475.1 - 2.3e-19 68.9 0.0 6.6e-19 67.4 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.20 AEO54475.1 - 1.8e-06 27.1 0.0 0.00059 18.8 0.0 2.9 3 0 0 3 3 3 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 AEO54475.1 - 4.3e-06 25.9 0.1 6.4e-06 25.3 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase ATP11 PF06644.6 AEO54475.1 - 0.0027 17.2 0.0 0.004 16.6 0.0 1.2 1 0 0 1 1 1 1 ATP11 protein His_biosynth PF00977.16 AEO54475.1 - 0.013 14.7 0.0 0.028 13.6 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein DUF3712 PF12505.3 AEO54476.1 - 4.6e-28 97.7 0.5 9.3e-28 96.7 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) GAF PF01590.21 AEO54476.1 - 0.063 13.4 0.0 0.42 10.7 0.0 2.1 2 0 0 2 2 2 0 GAF domain HCNGP PF07818.8 AEO54477.1 - 9.3e-16 57.6 0.0 4.8e-10 39.3 0.0 2.2 2 0 0 2 2 2 2 HCNGP-like protein SIS PF01380.17 AEO54478.1 - 1.7e-56 189.4 0.1 4.1e-30 104.0 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 AEO54478.1 - 9.6e-27 93.6 0.0 3e-18 65.6 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 AEO54478.1 - 1.9e-20 73.1 0.0 4.8e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 AEO54478.1 - 9.2e-12 44.7 0.0 2.2e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 AEO54478.1 - 6.6e-07 28.2 0.0 1.2e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 AEO54478.1 - 0.0026 17.4 0.0 0.32 10.7 0.0 2.6 2 0 0 2 2 2 1 SIS domain AAA PF00004.24 AEO54479.1 - 4.4e-43 146.6 0.0 8.8e-43 145.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 AEO54479.1 - 7.8e-08 32.5 0.0 6.2e-06 26.3 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 AEO54479.1 - 1.5e-06 28.0 0.1 3.7e-05 23.4 0.0 2.8 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 AEO54479.1 - 1.5e-06 28.2 0.0 7.7e-06 25.9 0.0 2.2 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 AEO54479.1 - 2.7e-06 27.5 0.0 0.001 19.2 0.0 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 AEO54479.1 - 7.4e-06 25.1 0.0 1.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 AEO54479.1 - 0.00022 20.2 0.0 0.00054 18.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 AEO54479.1 - 0.00032 20.4 0.0 0.00075 19.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 AEO54479.1 - 0.00077 20.2 0.4 0.0023 18.7 0.1 2.1 2 1 0 2 2 1 1 AAA domain AAA_14 PF13173.1 AEO54479.1 - 0.00097 19.0 0.0 0.0027 17.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AEO54479.1 - 0.0011 19.2 0.2 0.0081 16.4 0.0 2.4 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.8 AEO54479.1 - 0.0016 17.2 0.0 0.0031 16.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 AEO54479.1 - 0.0016 18.2 0.0 0.0063 16.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 AEO54479.1 - 0.0024 17.3 0.0 0.0054 16.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 AEO54479.1 - 0.0031 16.7 0.0 0.0063 15.6 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.1 AEO54479.1 - 0.0033 17.0 1.2 0.26 10.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 AEO54479.1 - 0.0045 17.1 0.0 0.0096 16.0 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Zeta_toxin PF06414.7 AEO54479.1 - 0.0045 16.0 0.0 0.012 14.7 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.21 AEO54479.1 - 0.0072 15.8 0.0 0.025 14.0 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_25 PF13481.1 AEO54479.1 - 0.0091 15.4 0.5 0.046 13.1 0.1 2.2 2 1 1 3 3 2 1 AAA domain AAA_3 PF07726.6 AEO54479.1 - 0.0097 15.5 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 AEO54479.1 - 0.012 15.4 0.1 0.056 13.2 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Thymidylate_kin PF02223.12 AEO54479.1 - 0.012 14.9 0.2 1.4 8.2 0.0 2.6 3 0 0 3 3 2 0 Thymidylate kinase DUF4200 PF13863.1 AEO54479.1 - 0.015 15.2 4.8 0.036 14.0 3.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) AAA_24 PF13479.1 AEO54479.1 - 0.018 14.6 0.1 0.04 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain HAUS-augmin3 PF14932.1 AEO54479.1 - 0.019 14.1 1.4 0.03 13.5 0.9 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 AAA_28 PF13521.1 AEO54479.1 - 0.021 14.7 0.0 0.047 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 AEO54479.1 - 0.024 14.7 0.0 0.064 13.2 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain KaiC PF06745.8 AEO54479.1 - 0.024 13.7 0.5 0.098 11.7 0.0 2.2 3 0 0 3 3 3 0 KaiC Arch_ATPase PF01637.13 AEO54479.1 - 0.027 14.1 0.6 0.13 11.9 0.0 2.4 2 1 0 2 2 2 0 Archaeal ATPase PhoH PF02562.11 AEO54479.1 - 0.03 13.5 0.0 0.056 12.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 AEO54479.1 - 0.039 13.5 0.0 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 NACHT domain UPF0079 PF02367.12 AEO54479.1 - 0.046 13.3 0.0 0.099 12.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 NB-ARC PF00931.17 AEO54479.1 - 0.046 12.5 0.3 0.4 9.4 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain FlaC_arch PF05377.6 AEO54479.1 - 0.059 13.2 1.0 0.33 10.8 0.5 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) AAA_30 PF13604.1 AEO54479.1 - 0.084 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain APG6 PF04111.7 AEO54479.1 - 0.092 11.7 2.1 0.13 11.2 1.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 eIF-1a PF01176.14 AEO54479.1 - 0.097 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 Parvo_NS1 PF01057.12 AEO54479.1 - 0.1 11.4 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_13 PF13166.1 AEO54479.1 - 0.18 10.2 3.3 6.4 5.0 2.0 2.2 2 0 0 2 2 2 0 AAA domain DivIC PF04977.10 AEO54479.1 - 0.44 10.0 4.6 2.8 7.4 1.8 2.8 2 0 0 2 2 2 0 Septum formation initiator AAA_23 PF13476.1 AEO54479.1 - 0.47 10.7 10.2 2.9 8.1 0.0 2.7 2 1 0 2 2 2 0 AAA domain IncA PF04156.9 AEO54479.1 - 0.57 9.7 5.1 1.1 8.8 3.5 1.4 1 0 0 1 1 1 0 IncA protein Protoglobin PF11563.3 AEO54481.1 - 2.6e-57 192.9 0.0 3.8e-57 192.3 0.0 1.2 1 0 0 1 1 1 1 Protoglobin Ribosomal_60s PF00428.14 AEO54481.1 - 0.041 14.2 11.5 0.082 13.3 8.0 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Acatn PF13000.2 AEO54481.1 - 0.16 10.4 0.0 0.21 10.0 0.0 1.1 1 0 0 1 1 1 0 Acetyl-coenzyme A transporter 1 3Beta_HSD PF01073.14 AEO54482.1 - 0.17 10.5 0.0 0.29 9.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Gln-synt_C PF00120.19 AEO54483.1 - 2.1e-56 190.9 0.0 2.5e-56 190.6 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 AEO54483.1 - 3e-19 68.3 0.0 6.8e-19 67.2 0.0 1.6 2 0 0 2 2 2 1 Glutamine synthetase, beta-Grasp domain GXWXG PF14231.1 AEO54483.1 - 0.094 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 GXWXG protein Epimerase PF01370.16 AEO54484.1 - 1.7e-27 96.4 0.1 1.8e-26 93.0 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 AEO54484.1 - 6.4e-15 54.8 0.2 9.1e-15 54.2 0.2 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 AEO54484.1 - 2.5e-13 49.5 1.8 2e-09 36.8 0.3 3.0 2 1 1 3 3 3 2 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 AEO54484.1 - 2.5e-11 42.8 0.0 8.8e-11 41.0 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 AEO54484.1 - 1.3e-10 40.6 0.1 1.6e-09 37.0 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.1 AEO54484.1 - 1.3e-09 38.3 1.4 1.4e-09 38.2 0.3 1.6 2 0 0 2 2 2 1 NADH(P)-binding adh_short PF00106.20 AEO54484.1 - 0.088 12.7 6.5 0.85 9.5 0.9 2.5 1 1 1 2 2 2 0 short chain dehydrogenase Ribosomal_60s PF00428.14 AEO54484.1 - 0.56 10.6 6.5 0.11 12.8 0.5 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein Glyco_hydro_71 PF03659.9 AEO54485.1 - 6.4e-139 462.7 0.0 7.4e-139 462.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 adh_short_C2 PF13561.1 AEO54486.1 - 3.4e-13 49.9 0.0 2.5e-11 43.7 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 AEO54486.1 - 1.8e-05 24.7 0.6 0.0035 17.2 0.1 2.2 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.5 AEO54486.1 - 0.0036 16.9 0.0 0.0049 16.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Pkinase PF00069.20 AEO54487.1 - 0.042 12.9 0.0 0.052 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain Peptidase_C70 PF12385.3 AEO54488.1 - 0.012 15.3 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Papain-like cysteine protease AvrRpt2 Peptidase_S28 PF05577.7 AEO54489.1 - 2e-48 165.0 0.0 9.3e-48 162.8 0.0 1.7 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 AEO54489.1 - 0.014 15.3 0.2 0.032 14.0 0.0 1.7 1 1 1 2 2 2 0 Alpha/beta hydrolase family Ferric_reduct PF01794.14 AEO54490.1 - 2.5e-19 69.5 14.2 6.5e-19 68.2 9.9 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 AEO54490.1 - 6.8e-16 58.5 0.0 1.5e-15 57.4 0.0 1.5 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 AEO54490.1 - 4e-11 42.7 0.0 8.7e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 AEO54490.1 - 0.00011 22.7 0.0 0.00038 21.0 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain SchA_CurD PF04486.7 AEO54490.1 - 0.015 15.1 0.2 0.063 13.1 0.0 2.1 2 0 0 2 2 2 0 SchA/CurD like domain TraV PF09676.5 AEO54490.1 - 0.019 15.6 0.3 0.019 15.6 0.2 2.0 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) Shisa PF13908.1 AEO54490.1 - 0.095 12.8 1.1 0.21 11.7 0.8 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Pex14_N PF04695.8 AEO54490.1 - 1.9 8.5 11.3 0.058 13.4 1.2 2.8 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ctr PF04145.10 AEO54491.1 - 1.7e-41 141.6 0.8 2.3e-41 141.2 0.6 1.2 1 0 0 1 1 1 1 Ctr copper transporter family TcdA_TcdB_pore PF12920.2 AEO54491.1 - 0.15 9.9 2.1 0.2 9.5 1.4 1.1 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain DUF204 PF02659.10 AEO54491.1 - 2 8.5 10.1 24 5.1 4.7 2.9 2 1 0 2 2 2 0 Domain of unknown function DUF AzlD PF05437.7 AEO54491.1 - 2.3 8.1 8.1 9.4 6.2 0.6 2.4 2 0 0 2 2 2 0 Branched-chain amino acid transport protein (AzlD) DUF457 PF04307.9 AEO54491.1 - 4.3 6.6 6.7 4.9 6.4 4.0 1.7 1 1 0 1 1 1 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) 3Beta_HSD PF01073.14 AEO54492.1 - 2.2e-22 79.1 0.0 1.2e-13 50.4 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 AEO54492.1 - 1.2e-13 51.0 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 AEO54492.1 - 4.1e-09 35.7 0.1 2.7e-06 26.5 0.0 3.0 2 1 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.1 AEO54492.1 - 7e-07 29.4 0.0 4.9e-06 26.6 0.0 2.4 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 AEO54492.1 - 2e-06 27.8 0.1 5e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO54492.1 - 2.1e-05 24.2 0.0 4.1e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 AEO54492.1 - 0.0012 17.7 0.0 0.0019 17.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.12 AEO54492.1 - 0.14 12.6 0.0 0.43 11.0 0.0 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Pkinase PF00069.20 AEO54494.1 - 6.3e-19 68.1 0.0 4.1e-18 65.4 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO54494.1 - 3.7e-08 32.7 0.0 6.8e-08 31.9 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 AEO54494.1 - 0.006 15.6 0.0 0.0092 15.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Toxin_12 PF07740.7 AEO54498.1 - 0.00044 20.6 6.2 0.00058 20.2 4.3 1.3 1 0 0 1 1 1 1 Ion channel inhibitory toxin Lysis_S PF04971.7 AEO54499.1 - 0.023 14.3 0.8 0.22 11.2 0.3 2.0 1 1 1 2 2 2 0 Lysis protein S Asn_synthase PF00733.16 AEO54500.1 - 2.9e-14 53.1 0.0 3.1e-14 53.0 0.0 1.0 1 0 0 1 1 1 1 Asparagine synthase NAD_synthase PF02540.12 AEO54500.1 - 0.006 15.5 0.0 0.0061 15.4 0.0 1.1 1 0 0 1 1 1 1 NAD synthase tRNA_Me_trans PF03054.11 AEO54500.1 - 0.054 12.0 0.0 0.06 11.8 0.0 1.1 1 0 0 1 1 1 0 tRNA methyl transferase Asn_synthase PF00733.16 AEO54501.1 - 2.8e-28 99.1 0.0 3.5e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase Docking PF08990.6 AEO54502.1 - 0.064 12.5 1.0 0.13 11.5 0.7 1.5 1 0 0 1 1 1 0 Erythronolide synthase docking HMG_box_2 PF09011.5 AEO54503.1 - 0.0002 21.6 0.0 0.00038 20.7 0.0 1.4 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.14 AEO54503.1 - 0.0019 18.4 0.0 0.0037 17.4 0.0 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box PAP2_3 PF14378.1 AEO54504.1 - 6.1e-23 81.3 10.5 9.3e-21 74.2 1.5 2.7 3 0 0 3 3 3 2 PAP2 superfamily PAP2 PF01569.16 AEO54504.1 - 0.00058 19.5 3.3 0.0016 18.1 2.1 1.8 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.1 AEO54504.1 - 0.025 14.8 0.3 0.025 14.8 0.2 2.1 2 0 0 2 2 2 0 PAP2 superfamily C-terminal Pkinase PF00069.20 AEO54506.1 - 0.0002 20.5 0.0 0.00031 19.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO54506.1 - 0.0005 19.2 0.0 0.00075 18.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AEO54506.1 - 0.06 13.0 4.4 0.077 12.7 0.8 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family APH PF01636.18 AEO54507.1 - 1.2e-08 34.9 0.0 1.7e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Glyco_hydro_2_N PF02837.13 AEO54508.1 - 3.3e-27 95.0 0.0 6.6e-27 94.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 AEO54508.1 - 4.8e-09 36.6 0.0 1e-08 35.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 AEO54508.1 - 2.9e-07 29.7 0.1 9.9e-07 27.9 0.0 1.8 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_61 PF03443.9 AEO54509.1 - 6.2e-46 156.9 0.4 6.2e-46 156.9 0.3 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 AEO54509.1 - 8.4e-13 47.7 16.4 8.4e-13 47.7 11.4 2.4 2 0 0 2 2 2 1 Fungal cellulose binding domain zf-C2H2 PF00096.21 AEO54510.1 - 0.001 19.2 20.4 0.032 14.5 0.5 4.9 3 1 1 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 AEO54510.1 - 0.0054 16.8 7.5 0.35 11.0 0.1 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 AEO54510.1 - 0.019 15.1 0.8 1.1 9.5 0.0 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Zn_clus PF00172.13 AEO54510.1 - 0.31 10.9 17.9 0.24 11.3 7.3 2.9 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.1 AEO54510.1 - 4 7.8 14.6 0.065 13.5 3.6 3.0 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_4 PF13894.1 AEO54510.1 - 6.3 7.3 29.3 0.24 11.8 1.0 5.3 5 0 0 5 5 5 0 C2H2-type zinc finger LRR_6 PF13516.1 AEO54511.1 - 0.2 11.8 0.6 36 4.8 0.2 3.1 3 0 0 3 3 3 0 Leucine Rich repeat Glyco_hydro_11 PF00457.12 AEO54512.1 - 5.2e-51 172.5 14.9 6.2e-51 172.3 10.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 W_rich_C PF07483.6 AEO54512.1 - 0.011 15.3 3.9 0.02 14.5 1.4 2.2 1 1 1 2 2 2 0 Tryptophan-rich Synechocystis species C-terminal domain Zn_clus PF00172.13 AEO54515.1 - 0.0014 18.5 11.0 0.026 14.4 7.6 2.4 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NB-ARC PF00931.17 AEO54516.1 - 5e-13 48.5 0.0 8.9e-13 47.7 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 AEO54516.1 - 0.00019 21.5 0.0 0.00055 20.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AEO54516.1 - 0.0012 18.8 1.1 0.008 16.1 0.0 2.9 2 2 1 3 3 3 1 AAA ATPase domain NACHT PF05729.7 AEO54516.1 - 0.014 15.0 0.0 0.028 14.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Flu_M2 PF00599.12 AEO54516.1 - 0.07 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Influenza Matrix protein (M2) Beta-lactamase PF00144.19 AEO54517.1 - 1.4e-52 178.7 0.0 2.2e-52 178.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 AEO54517.1 - 1.3e-05 24.9 0.0 5.2e-05 23.0 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3471) D123 PF07065.9 AEO54518.1 - 4e-05 22.8 0.0 6e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 D123 DUF4343 PF14243.1 AEO54518.1 - 0.035 13.9 0.0 0.063 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4343) Beta-lactamase PF00144.19 AEO54520.1 - 4e-57 193.7 0.1 7.3e-57 192.8 0.1 1.3 1 1 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 AEO54520.1 - 5.1e-13 48.7 0.0 1.1e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Pab87_oct PF13969.1 AEO54520.1 - 0.029 14.4 0.0 0.062 13.3 0.0 1.6 1 0 0 1 1 1 0 Pab87 octamerisation domain Mucin PF01456.12 AEO54521.1 - 0.0095 15.7 1.2 0.0095 15.7 0.8 2.5 2 0 0 2 2 2 1 Mucin-like glycoprotein SSP160 PF06933.6 AEO54521.1 - 1 7.2 22.9 0.32 8.9 4.4 2.3 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 Fungal_trans PF04082.13 AEO54522.1 - 0.00036 19.5 0.0 0.00063 18.7 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain PIGA PF08288.7 AEO54522.1 - 0.16 12.3 0.2 0.4 11.0 0.1 1.6 1 0 0 1 1 1 0 PIGA (GPI anchor biosynthesis) Zn_clus PF00172.13 AEO54522.1 - 2.7 7.9 13.4 4.9 7.1 9.3 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_17 PF00332.13 AEO54524.1 - 9.8e-08 31.3 1.0 3e-05 23.2 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 Calcyon PF06387.6 AEO54524.1 - 0.15 11.3 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 D1 dopamine receptor-interacting protein (calcyon) Amidoligase_2 PF12224.3 AEO54525.1 - 5.3e-13 49.1 0.0 1.5e-08 34.5 0.0 3.0 2 1 0 3 3 3 2 Putative amidoligase enzyme DUF1275 PF06912.6 AEO54527.1 - 1.7e-34 118.8 14.0 2.1e-34 118.5 9.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Cupin_1 PF00190.17 AEO54528.1 - 1.9e-31 108.4 0.0 3.7e-16 58.8 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 AEO54528.1 - 1.4e-26 91.7 3.5 7e-14 51.0 0.3 2.4 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 AEO54528.1 - 4.6e-10 39.3 0.3 1.8e-05 24.4 0.1 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_3 PF05899.7 AEO54528.1 - 3.8e-09 35.7 0.2 0.0035 16.7 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) MannoseP_isomer PF01050.13 AEO54528.1 - 0.00026 20.6 0.0 0.015 14.8 0.0 2.1 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase ARD PF03079.9 AEO54528.1 - 0.0045 16.9 0.4 3.4 7.6 0.1 2.3 2 0 0 2 2 2 2 ARD/ARD' family Cupin_4 PF08007.7 AEO54528.1 - 0.13 11.4 0.1 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein AAA PF00004.24 AEO54529.1 - 8.4e-19 68.0 0.0 1.6e-18 67.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 AEO54529.1 - 0.00015 22.5 0.0 0.00015 22.5 0.0 3.3 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 AEO54529.1 - 0.0012 17.9 0.0 0.003 16.6 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 AEO54529.1 - 0.0023 17.9 0.0 0.0059 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 AEO54529.1 - 0.0024 17.9 0.1 0.012 15.7 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 AEO54529.1 - 0.008 15.9 0.1 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 AEO54529.1 - 0.018 14.7 0.1 0.059 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF2457 PF10446.4 AEO54529.1 - 0.021 13.6 29.0 0.011 14.5 18.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) AAA_11 PF13086.1 AEO54529.1 - 0.2 11.2 6.6 0.85 9.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain SAPS PF04499.10 AEO54529.1 - 0.45 9.1 9.4 0.62 8.6 6.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.7 AEO54529.1 - 0.78 7.5 33.2 1.1 7.0 23.0 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 AEO54529.1 - 1.4 7.3 30.0 1.9 6.8 20.8 1.1 1 0 0 1 1 1 0 Daxx Family FLO_LFY PF01698.11 AEO54529.1 - 1.7 7.4 17.3 2.9 6.6 12.0 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein Ycf1 PF05758.7 AEO54529.1 - 2.3 5.8 13.2 3.7 5.1 9.1 1.3 1 0 0 1 1 1 0 Ycf1 MIP-T3 PF10243.4 AEO54529.1 - 4.9 5.5 33.3 7.3 4.9 23.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 zf-RING_2 PF13639.1 AEO54530.1 - 2.1e-08 33.8 5.9 2.1e-08 33.8 4.1 1.9 2 0 0 2 2 2 1 Ring finger domain FANCL_C PF11793.3 AEO54530.1 - 5e-06 26.3 4.7 5e-06 26.3 3.2 1.7 2 0 0 2 2 2 1 FANCL C-terminal domain zf-rbx1 PF12678.2 AEO54530.1 - 0.0022 18.0 3.2 0.0022 18.0 2.2 1.8 2 0 0 2 2 2 1 RING-H2 zinc finger PHD PF00628.24 AEO54530.1 - 0.0067 16.0 7.8 0.013 15.1 5.4 1.5 1 0 0 1 1 1 1 PHD-finger zf-C3HC4_2 PF13923.1 AEO54530.1 - 0.022 14.8 6.2 0.022 14.8 4.3 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 AEO54530.1 - 0.037 14.0 7.7 0.082 12.9 5.4 1.6 1 0 0 1 1 1 0 RING-variant domain zf-Apc11 PF12861.2 AEO54530.1 - 0.11 12.3 5.7 0.032 14.0 1.4 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 AEO54530.1 - 2.5 7.8 13.5 0.036 13.8 4.1 1.9 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 AEO54530.1 - 8.7 6.1 11.7 0.12 12.0 2.8 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) MFS_1 PF07690.11 AEO54531.1 - 3.3e-43 147.7 22.8 3.3e-43 147.7 15.8 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.13 AEO54531.1 - 0.00052 18.9 0.3 0.0026 16.6 0.0 2.0 2 1 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO54531.1 - 0.72 9.8 12.6 0.032 14.1 4.8 1.7 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1996 PF09362.5 AEO54532.1 - 1e-31 110.4 1.3 5.2e-21 75.4 0.1 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF1996) NTP_transf_2 PF01909.18 AEO54533.1 - 1.5e-07 31.6 0.0 3.3e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nuc-transf PF10127.4 AEO54533.1 - 0.00021 20.7 0.0 0.00038 19.8 0.0 1.4 1 0 0 1 1 1 1 Predicted nucleotidyltransferase Hemerythrin PF01814.18 AEO54533.1 - 0.13 12.3 0.1 0.32 11.1 0.1 1.7 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain AAA_12 PF13087.1 AEO54534.1 - 8.4e-36 123.2 0.0 1.6e-35 122.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 AEO54534.1 - 5.6e-26 91.5 0.2 4.1e-25 88.7 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AEO54534.1 - 4.2e-10 39.2 0.7 1.2e-09 37.7 0.5 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 AEO54534.1 - 1.8e-06 27.6 0.0 0.0003 20.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain PhoH PF02562.11 AEO54534.1 - 0.031 13.5 0.0 0.059 12.5 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein DUF2075 PF09848.4 AEO54534.1 - 0.14 11.1 0.0 0.29 10.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) WD40 PF00400.27 AEO54535.1 - 3.6e-20 71.0 1.5 0.00097 18.9 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat WD40 PF00400.27 AEO54536.1 - 1.3e-33 113.6 1.8 5.3e-12 45.1 0.0 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat PUL PF08324.6 AEO54537.1 - 2.7e-52 177.2 0.0 3.4e-52 176.8 0.0 1.1 1 0 0 1 1 1 1 PUL domain PFU PF09070.6 AEO54537.1 - 6.1e-43 145.5 0.0 1.4e-42 144.3 0.0 1.6 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 AEO54537.1 - 4.9e-35 118.1 15.5 1.2e-06 28.2 0.0 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat SRR1 PF07985.7 AEO54539.1 - 0.00064 19.6 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 SRR1 PAN_4 PF14295.1 AEO54540.1 - 3.5e-05 23.4 4.7 6.7e-05 22.5 3.3 1.5 1 0 0 1 1 1 1 PAN domain NAD_binding_10 PF13460.1 AEO54541.1 - 5e-12 46.1 0.0 1.6e-11 44.5 0.0 1.7 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 AEO54541.1 - 1.8e-07 30.8 0.0 2.5e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 AEO54541.1 - 0.00028 19.8 0.0 0.00042 19.3 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.19 AEO54541.1 - 0.0019 18.4 0.0 0.0037 17.5 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 AEO54541.1 - 0.011 14.4 0.0 0.016 13.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 AEO54541.1 - 0.016 15.1 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase NmrA PF05368.8 AEO54541.1 - 0.019 14.2 0.0 0.058 12.6 0.0 1.8 2 0 0 2 2 2 0 NmrA-like family KR PF08659.5 AEO54541.1 - 0.089 12.4 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 KR domain DUF4192 PF13830.1 AEO54541.1 - 0.12 12.0 6.6 0.061 12.9 0.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4192) Pox_A32 PF04665.7 AEO54541.1 - 0.21 10.8 0.0 0.43 9.8 0.0 1.4 1 1 0 1 1 1 0 Poxvirus A32 protein Ferric_reduct PF01794.14 AEO54542.1 - 3.9e-15 56.0 11.7 3.9e-15 56.0 8.1 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 AEO54542.1 - 3.9e-10 39.5 0.0 1.2e-05 25.1 0.1 2.6 3 0 0 3 3 3 2 FAD-binding domain NAD_binding_6 PF08030.7 AEO54542.1 - 5.3e-05 23.1 0.0 0.17 11.7 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain YadA_stalk PF05662.9 AEO54543.1 - 0.041 13.6 7.2 0.21 11.3 1.0 3.4 2 1 0 2 2 2 0 Coiled stalk of trimeric autotransporter adhesin SseC PF04888.7 AEO54543.1 - 0.52 9.5 7.7 0.63 9.3 5.4 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Zip PF02535.17 AEO54545.1 - 0.18 10.7 7.3 0.22 10.4 5.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter PAT1 PF09770.4 AEO54545.1 - 1.5 6.9 24.2 1.7 6.7 16.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MFS_1 PF07690.11 AEO54546.1 - 3.3e-17 62.2 39.1 1.4e-15 56.9 17.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-C2H2_4 PF13894.1 AEO54548.1 - 0.018 15.3 14.7 2.4 8.6 0.8 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 AEO54548.1 - 0.025 14.7 5.4 3.3 7.9 0.2 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 AEO54548.1 - 0.045 13.9 5.7 0.45 10.8 0.2 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 AEO54548.1 - 0.069 13.4 0.8 0.069 13.4 0.6 3.2 3 1 0 3 3 3 0 Zinc-finger double domain zf-C2H2 PF00096.21 AEO54548.1 - 0.45 10.9 9.4 7.4 7.1 0.4 3.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type Fungal_trans PF04082.13 AEO54550.1 - 2.2e-24 85.7 0.4 3.4e-24 85.1 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO54550.1 - 2.7e-08 33.5 12.9 5.5e-08 32.5 9.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Brr6_like_C_C PF10104.4 AEO54551.1 - 1.2e-37 128.4 0.3 1.6e-37 128.0 0.2 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Med26 PF08711.6 AEO54552.1 - 2.7e-14 52.3 0.0 4.8e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Pkinase PF00069.20 AEO54553.1 - 1.5e-42 145.5 0.5 2.2e-25 89.3 0.2 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AEO54553.1 - 3.6e-15 55.7 0.3 1.2e-10 40.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Cupin_1 PF00190.17 AEO54554.1 - 2.9e-07 30.0 0.0 6.1e-07 28.9 0.0 1.5 1 1 0 1 1 1 1 Cupin Cupin_2 PF07883.6 AEO54554.1 - 1.4e-05 24.4 0.0 6e-05 22.4 0.0 1.9 1 1 0 1 1 1 1 Cupin domain DUF3328 PF11807.3 AEO54556.1 - 9.2e-42 143.1 0.1 1e-41 143.0 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) CFEM PF05730.6 AEO54559.1 - 2.6e-16 59.1 13.0 4.4e-16 58.4 9.0 1.4 1 0 0 1 1 1 1 CFEM domain F-box-like PF12937.2 AEO54561.1 - 0.0074 15.9 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 AEO54561.1 - 0.019 14.6 0.1 0.032 13.8 0.1 1.4 1 0 0 1 1 1 0 F-box domain F-box-like_2 PF13013.1 AEO54561.1 - 0.095 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 F-box-like domain Pkinase PF00069.20 AEO54562.1 - 7.7e-05 21.9 0.0 0.00013 21.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 AEO54562.1 - 0.00015 21.5 0.2 0.00015 21.5 0.1 3.1 4 0 0 4 4 4 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 AEO54562.1 - 0.04 13.0 0.0 0.064 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase RIO1 PF01163.17 AEO54562.1 - 0.13 11.6 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 AEO54563.1 - 4.1e-14 52.8 0.0 7.1e-14 52.1 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 AEO54563.1 - 0.00016 20.4 0.0 0.23 10.0 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) Tyrosinase PF00264.15 AEO54564.1 - 1.7e-50 172.2 0.1 2.2e-50 171.8 0.1 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase DnaJ PF00226.26 AEO54565.1 - 8.8e-20 70.2 1.7 8.8e-20 70.2 1.2 2.7 2 0 0 2 2 2 1 DnaJ domain RRM_1 PF00076.17 AEO54566.1 - 1.4e-10 40.6 0.0 2.2e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO54566.1 - 1.3e-09 37.7 0.0 2.3e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO54566.1 - 1.4e-07 31.3 0.0 2.5e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 AEO54566.1 - 0.00034 20.3 0.1 0.00062 19.4 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 AEO54566.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 RNA binding motif Sterol_MT_C PF08498.5 AEO54567.1 - 2.8e-29 100.8 0.5 4.4e-29 100.2 0.3 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 AEO54567.1 - 1.2e-21 77.0 0.0 2.3e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO54567.1 - 1.5e-18 66.8 0.0 2.3e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO54567.1 - 3.5e-14 52.8 0.0 6e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO54567.1 - 5.5e-14 52.3 0.0 1e-13 51.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 AEO54567.1 - 3.3e-13 49.3 0.0 5e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 AEO54567.1 - 5.1e-13 49.3 0.0 1.7e-12 47.6 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO54567.1 - 6.2e-12 46.0 0.0 1.9e-11 44.5 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AEO54567.1 - 9.3e-11 41.2 0.0 1.7e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 AEO54567.1 - 2.9e-10 40.1 0.0 7.7e-10 38.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AEO54567.1 - 1.1e-05 24.8 0.0 2.1e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 AEO54567.1 - 0.00024 20.3 0.0 0.0006 19.0 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.5 AEO54567.1 - 0.00043 19.8 0.0 0.00067 19.2 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PCMT PF01135.14 AEO54567.1 - 0.00067 19.2 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_29 PF03141.11 AEO54567.1 - 0.0011 17.4 0.1 0.002 16.5 0.0 1.4 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MetW PF07021.7 AEO54567.1 - 0.0017 17.7 0.0 0.0033 16.8 0.0 1.5 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW RrnaAD PF00398.15 AEO54567.1 - 0.004 16.2 0.0 0.0067 15.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_24 PF13578.1 AEO54567.1 - 0.0054 17.5 0.0 0.022 15.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.13 AEO54567.1 - 0.012 14.8 0.0 0.025 13.7 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_32 PF13679.1 AEO54567.1 - 0.034 13.8 0.0 0.07 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.6 AEO54567.1 - 0.036 13.4 0.0 0.063 12.6 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Met_10 PF02475.11 AEO54567.1 - 0.088 12.3 0.1 0.16 11.5 0.0 1.6 2 0 0 2 2 2 0 Met-10+ like-protein UPF0020 PF01170.13 AEO54567.1 - 0.12 11.9 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Transket_pyr PF02779.19 AEO54568.1 - 3.4e-46 156.9 0.0 4.7e-46 156.5 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 AEO54568.1 - 3.5e-35 120.6 0.1 1.1e-34 119.0 0.0 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain Aminotran_5 PF00266.14 AEO54568.1 - 0.071 11.8 0.0 0.18 10.5 0.0 1.6 2 0 0 2 2 2 0 Aminotransferase class-V AIG2_2 PF13772.1 AEO54570.1 - 1.8e-06 27.9 0.0 0.014 15.5 0.0 2.4 2 0 0 2 2 2 2 AIG2-like family AIG2 PF06094.7 AEO54570.1 - 0.00075 19.9 0.0 0.0014 19.0 0.0 1.6 1 1 0 1 1 1 1 AIG2-like family DUF914 PF06027.7 AEO54571.1 - 2.7e-105 351.9 16.1 3.5e-105 351.5 11.2 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 AEO54571.1 - 9.1e-08 32.1 26.9 6.3e-07 29.4 4.6 2.5 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 AEO54571.1 - 0.0025 16.7 14.0 0.0041 16.0 9.7 1.3 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 AEO54571.1 - 0.0026 17.4 20.6 0.039 13.5 2.4 2.5 2 1 0 2 2 2 2 Triose-phosphate Transporter family Chorion_2 PF03964.10 AEO54571.1 - 0.1 13.1 0.4 0.18 12.3 0.3 1.3 1 0 0 1 1 1 0 Chorion family 2 FUSC-like PF12805.2 AEO54571.1 - 0.48 9.3 8.9 0.029 13.3 1.5 2.2 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS CVNH PF08881.5 AEO54574.1 - 3.5e-34 117.1 1.2 5.8e-34 116.4 0.8 1.4 1 0 0 1 1 1 1 CVNH domain LysM PF01476.15 AEO54574.1 - 2.6e-16 59.2 0.0 5.1e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 LysM domain Rick_17kDa_Anti PF05433.10 AEO54574.1 - 9.7e-09 34.7 18.5 2.5e-08 33.4 12.8 1.8 1 0 0 1 1 1 1 Glycine zipper 2TM domain Zip PF02535.17 AEO54574.1 - 0.005 15.8 2.4 0.008 15.2 1.7 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter DUF2076 PF09849.4 AEO54574.1 - 0.0055 16.7 6.8 0.0055 16.7 4.7 1.8 2 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2076) Gly-zipper_YMGG PF13441.1 AEO54574.1 - 0.0063 16.0 16.5 0.012 15.0 11.5 1.4 1 0 0 1 1 1 1 YMGG-like Gly-zipper DUF533 PF04391.7 AEO54574.1 - 0.017 14.5 1.4 0.017 14.5 1.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF533) Gly-zipper_Omp PF13488.1 AEO54574.1 - 0.063 12.9 20.0 0.2 11.3 13.4 2.1 1 1 1 2 2 2 0 Glycine zipper TraT PF05818.7 AEO54574.1 - 0.074 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein U79_P34 PF03064.11 AEO54574.1 - 0.074 12.5 9.2 0.14 11.6 6.4 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Ycf1 PF05758.7 AEO54574.1 - 0.2 9.3 1.5 0.24 9.1 1.0 1.1 1 0 0 1 1 1 0 Ycf1 Gly-zipper_OmpA PF13436.1 AEO54574.1 - 0.59 9.8 14.7 0.093 12.3 6.4 2.3 1 1 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain PVL_ORF50 PF07768.6 AEO54574.1 - 0.78 9.7 12.5 1.4 8.9 8.7 1.3 1 0 0 1 1 1 0 PVL ORF-50-like family Caldesmon PF02029.10 AEO54574.1 - 1.4 7.2 21.8 2.2 6.5 15.1 1.2 1 0 0 1 1 1 0 Caldesmon DUF788 PF05620.6 AEO54574.1 - 1.4 8.7 2.9 2.8 7.7 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF788) Peptidase_S49_N PF08496.5 AEO54574.1 - 1.5 8.5 4.6 2.7 7.7 3.2 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal MIP-T3 PF10243.4 AEO54574.1 - 2.1 6.7 15.9 0.35 9.2 8.6 1.3 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 PAP_assoc PF03828.14 AEO54577.1 - 9.1e-18 63.9 0.1 2.2e-17 62.7 0.1 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase Borrelia_P83 PF05262.6 AEO54577.1 - 8.6 4.5 6.2 13 3.9 4.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Abhydrolase_1 PF00561.15 AEO54579.1 - 4.5e-18 65.6 0.1 4.3e-17 62.4 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 AEO54579.1 - 1.6e-08 34.6 6.9 1.6e-08 34.6 4.8 2.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.15 AEO54579.1 - 0.00065 19.1 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Phosphoprotein PF00922.12 AEO54579.1 - 0.15 11.2 3.0 0.22 10.6 2.1 1.2 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein SR-25 PF10500.4 AEO54579.1 - 7.6 5.9 9.7 13 5.1 6.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein APG6 PF04111.7 AEO54580.1 - 3.2 6.6 3.8 5.1 6.0 2.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 MFS_1 PF07690.11 AEO54581.1 - 5.3e-21 74.7 40.1 9.7e-21 73.8 21.6 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily CHASE2 PF05226.6 AEO54581.1 - 0.37 9.9 3.1 0.77 8.9 2.1 1.5 1 0 0 1 1 1 0 CHASE2 domain DUF4371 PF14291.1 AEO54583.1 - 0.072 12.6 0.0 0.082 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4371) zf-C2H2_4 PF13894.1 AEO54584.1 - 0.00081 19.5 1.4 0.25 11.7 0.2 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger DUF866 PF05907.8 AEO54584.1 - 0.12 11.8 0.3 0.16 11.4 0.2 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) zf-C2H2 PF00096.21 AEO54584.1 - 0.35 11.2 4.1 0.49 10.8 0.1 2.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2HC_2 PF13913.1 AEO54584.1 - 0.45 10.2 2.9 2.9 7.6 0.1 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.1 AEO54584.1 - 0.82 10.0 0.1 0.82 10.0 0.0 2.9 3 0 0 3 3 3 0 Zinc-finger double domain NUDIX PF00293.23 AEO54585.1 - 7.1e-20 71.0 0.1 9.8e-20 70.5 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain NUDIX PF00293.23 AEO54586.1 - 1.1e-06 28.3 0.2 2.4e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 NUDIX domain DUF3105 PF11303.3 AEO54588.1 - 0.088 12.6 0.2 2.2 8.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3105) Tyrosinase PF00264.15 AEO54589.1 - 8e-50 170.0 2.0 9.7e-50 169.7 1.4 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase SSP160 PF06933.6 AEO54590.1 - 2.4 6.0 13.7 3.5 5.4 9.5 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3311 PF11755.3 AEO54591.1 - 0.059 12.9 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3311) GST_N_3 PF13417.1 AEO54592.1 - 1.3e-26 92.5 0.0 2.6e-26 91.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 AEO54592.1 - 2.5e-17 62.6 0.0 5.1e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 AEO54592.1 - 8.1e-09 35.2 0.1 1.8e-08 34.1 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 AEO54592.1 - 0.00011 22.2 0.1 0.0009 19.3 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 AEO54592.1 - 0.019 14.9 0.0 0.075 13.0 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 AEO54592.1 - 0.071 13.5 0.0 0.17 12.3 0.0 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 AEO54592.1 - 0.13 12.2 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin SIR2 PF02146.12 AEO54594.1 - 1.5e-53 181.1 0.0 2.2e-53 180.6 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DMPK_coil PF08826.5 AEO54594.1 - 0.019 14.8 0.9 0.036 13.9 0.7 1.4 1 0 0 1 1 1 0 DMPK coiled coil domain like TPP_enzyme_M PF00205.17 AEO54594.1 - 0.076 12.7 0.0 0.44 10.3 0.0 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Cep57_CLD_2 PF14197.1 AEO54594.1 - 0.092 12.6 3.8 0.17 11.8 2.6 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 FHA PF00498.21 AEO54596.1 - 3e-16 59.2 0.0 8.2e-16 57.8 0.0 1.8 1 0 0 1 1 1 1 FHA domain Romo1 PF10247.4 AEO54597.1 - 2.3e-29 101.3 10.7 2.9e-29 101.0 7.4 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Spore_YabQ PF09578.5 AEO54597.1 - 0.51 10.3 3.7 3.8 7.5 2.2 2.0 1 1 1 2 2 2 0 Spore cortex protein YabQ (Spore_YabQ) Cu-oxidase_3 PF07732.10 AEO54598.1 - 3e-42 143.0 5.6 2.1e-40 137.1 0.0 3.5 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 AEO54598.1 - 9.3e-33 113.3 0.0 4.3e-30 104.7 0.0 2.5 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 AEO54598.1 - 2.3e-32 111.3 3.6 2.3e-32 111.3 2.5 2.8 4 0 0 4 4 4 1 Multicopper oxidase TP_methylase PF00590.15 AEO54599.1 - 3.8e-44 150.9 0.1 2.5e-43 148.2 0.0 2.2 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Sirohm_synth_C PF14823.1 AEO54599.1 - 3.3e-09 35.9 0.1 1.8e-05 23.9 0.0 3.0 4 0 0 4 4 4 2 Sirohaem biosynthesis protein C-terminal NAD_binding_7 PF13241.1 AEO54599.1 - 8.8e-08 32.3 0.0 0.0019 18.4 0.0 2.5 2 0 0 2 2 2 2 Putative NAD(P)-binding Sirohm_synth_M PF14824.1 AEO54599.1 - 2.4e-05 23.2 0.0 5.1e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central DUF2201_N PF13203.1 AEO54599.1 - 0.18 10.9 4.6 0.07 12.2 0.3 2.2 2 0 0 2 2 2 0 Putative metallopeptidase domain Pex14_N PF04695.8 AEO54599.1 - 4.7 7.2 8.9 0.89 9.5 1.9 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ras PF00071.17 AEO54600.1 - 5e-54 182.0 0.0 5.8e-54 181.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AEO54600.1 - 3.7e-16 59.7 0.0 5.2e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AEO54600.1 - 4.4e-09 35.8 0.0 8.9e-09 34.8 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 AEO54600.1 - 0.0015 17.7 0.0 0.0019 17.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 AEO54600.1 - 0.0047 16.1 0.0 0.0063 15.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 AEO54600.1 - 0.012 15.5 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.15 AEO54600.1 - 0.017 13.8 0.0 0.032 12.9 0.0 1.3 1 1 0 1 1 1 0 G-protein alpha subunit ABC_tran PF00005.22 AEO54600.1 - 0.098 12.9 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Arch_ATPase PF01637.13 AEO54600.1 - 0.13 11.9 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase CWC25 PF12542.3 AEO54601.1 - 3.2e-27 94.7 0.3 3.2e-27 94.7 0.2 4.2 4 1 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.4 AEO54601.1 - 3.6e-11 42.8 5.5 3.6e-11 42.8 3.8 5.2 5 0 0 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR PCI PF01399.22 AEO54602.1 - 3.7e-19 68.9 0.3 2.4e-18 66.3 0.0 2.5 2 1 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 AEO54602.1 - 4.9e-07 29.6 0.1 1.1e-06 28.4 0.1 1.5 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_10 PF13374.1 AEO54602.1 - 0.012 15.4 4.9 1.7 8.7 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Pkinase_Tyr PF07714.12 AEO54602.1 - 0.032 13.3 0.1 0.16 10.9 0.0 1.9 2 0 0 2 2 2 0 Protein tyrosine kinase TPR_12 PF13424.1 AEO54602.1 - 0.048 13.5 5.0 0.21 11.5 0.1 3.4 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 AEO54602.1 - 0.13 12.0 3.8 4.4 7.3 0.2 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 AEO54602.1 - 0.3 10.7 2.5 1.8 8.3 0.3 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 AEO54602.1 - 0.69 9.8 5.4 0.28 11.0 0.3 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_C65 PF10275.4 AEO54603.1 - 4.2e-68 229.3 0.0 5.3e-68 228.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain PLRV_ORF5 PF01690.12 AEO54603.1 - 0.038 13.1 7.0 0.058 12.5 4.8 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF2360 PF10152.4 AEO54603.1 - 6.5 7.0 7.2 4.7 7.5 0.6 2.4 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) BPL_LplA_LipB PF03099.14 AEO54604.1 - 9e-08 32.1 0.1 8.2e-06 25.8 0.0 2.3 2 0 0 2 2 2 2 Biotin/lipoate A/B protein ligase family Rsm22 PF09243.5 AEO54605.1 - 3.6e-32 111.5 0.0 5e-30 104.4 0.0 2.7 2 1 0 2 2 2 2 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.1 AEO54605.1 - 0.0034 17.1 0.0 0.0092 15.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO54605.1 - 0.016 15.8 0.4 0.54 10.8 0.1 3.0 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.7 AEO54605.1 - 0.093 13.2 0.0 0.28 11.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Thioredoxin PF00085.15 AEO54606.1 - 1.2e-27 95.5 0.0 1.5e-27 95.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 AEO54606.1 - 3.7e-08 33.5 0.1 1e-07 32.1 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 AEO54606.1 - 9.2e-08 32.1 0.7 1.8e-07 31.1 0.0 1.8 2 1 0 2 2 2 1 Thioredoxin-like Thioredoxin_7 PF13899.1 AEO54606.1 - 2e-05 24.5 0.0 2.7e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 AEO54606.1 - 0.00091 18.7 0.1 0.18 11.3 0.1 2.1 1 1 1 2 2 2 2 Redoxin AhpC-TSA PF00578.16 AEO54606.1 - 0.0036 16.9 0.0 0.086 12.5 0.0 2.0 1 1 1 2 2 2 1 AhpC/TSA family Thioredoxin_9 PF14595.1 AEO54606.1 - 0.0037 16.8 0.0 0.005 16.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Glutaredoxin PF00462.19 AEO54606.1 - 0.12 12.4 0.0 0.21 11.5 0.0 1.4 1 1 0 1 1 1 0 Glutaredoxin HyaE PF07449.6 AEO54606.1 - 0.15 11.9 0.0 0.24 11.3 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE DUF2763 PF10961.3 AEO54606.1 - 0.68 10.3 0.1 0.68 10.3 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2763) Methyltrn_RNA_3 PF02598.12 AEO54607.1 - 1.2e-85 287.4 0.0 1.4e-85 287.2 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase SpoU_methylase PF00588.14 AEO54607.1 - 0.0034 17.2 0.0 0.12 12.2 0.0 2.1 2 0 0 2 2 2 1 SpoU rRNA Methylase family 4HBT PF03061.17 AEO54608.1 - 0.00011 22.2 0.5 0.00083 19.4 0.0 2.2 2 0 0 2 2 2 1 Thioesterase superfamily Pex14_N PF04695.8 AEO54608.1 - 0.63 10.0 4.2 0.8 9.7 2.1 1.9 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CAP_N PF01213.14 AEO54608.1 - 0.92 8.7 7.1 1.9 7.7 4.9 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal CPSase_L_D2 PF02786.12 AEO54609.1 - 9.5e-74 247.2 0.0 1.6e-73 246.4 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 AEO54609.1 - 7.7e-36 122.3 0.0 1.6e-35 121.3 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 AEO54609.1 - 3.8e-34 117.0 0.0 7.9e-34 116.0 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 AEO54609.1 - 1.1e-19 70.9 0.2 4.5e-19 68.9 0.0 2.1 3 0 0 3 3 3 1 ATP-grasp domain Biotin_lipoyl PF00364.17 AEO54609.1 - 3e-16 58.7 0.7 7.5e-16 57.5 0.5 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 AEO54609.1 - 7.3e-16 57.8 0.0 1.2e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 AEO54609.1 - 8.8e-08 31.6 0.0 1.8e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 AEO54609.1 - 1.4e-07 31.0 0.0 0.012 15.2 0.0 3.0 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 AEO54609.1 - 1.7e-07 30.8 0.0 4.1e-07 29.6 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 AEO54609.1 - 6.8e-05 22.7 0.0 0.00013 21.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.1 AEO54609.1 - 0.00041 20.6 0.0 0.76 10.1 0.0 2.8 2 0 0 2 2 2 2 HlyD family secretion protein ATP-grasp_5 PF13549.1 AEO54609.1 - 0.0029 16.8 0.0 0.0067 15.6 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD PF00529.15 AEO54609.1 - 0.0042 16.4 3.2 0.27 10.4 0.0 2.8 2 1 1 3 3 3 2 HlyD family secretion protein RimK PF08443.6 AEO54609.1 - 0.02 14.3 0.0 0.55 9.6 0.0 2.4 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Nairovirus_M PF07948.6 AEO54609.1 - 0.3 9.1 0.0 0.44 8.6 0.0 1.1 1 0 0 1 1 1 0 Nairovirus M polyprotein-like Pyridox_oxidase PF01243.15 AEO54610.1 - 9.6e-13 47.9 0.0 5.6e-12 45.5 0.0 2.0 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.2 AEO54610.1 - 0.017 14.9 0.0 0.73 9.6 0.0 2.1 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase Mem_trans PF03547.13 AEO54611.1 - 9.4e-52 175.5 0.0 1.2e-51 175.1 0.0 1.1 1 0 0 1 1 1 1 Membrane transport protein Pkinase PF00069.20 AEO54612.1 - 7.2e-49 166.2 0.0 5.2e-46 156.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AEO54612.1 - 2e-29 102.4 0.0 3.9e-28 98.2 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO54612.1 - 0.00016 20.7 0.0 0.00025 20.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 AEO54612.1 - 0.0017 17.2 0.1 0.0027 16.6 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 AEO54612.1 - 0.08 11.7 0.1 0.12 11.1 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 AEO54612.1 - 0.081 12.6 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family SUR7 PF06687.7 AEO54613.1 - 3e-36 124.9 6.3 3.6e-36 124.7 4.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 AEO54613.1 - 0.00075 19.2 14.6 0.00075 19.2 10.1 2.0 1 1 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Clc-like PF07062.7 AEO54613.1 - 0.16 11.1 4.6 0.26 10.5 3.2 1.2 1 0 0 1 1 1 0 Clc-like Amastin PF07344.6 AEO54613.1 - 0.67 9.5 15.6 0.48 10.0 9.0 1.9 2 0 0 2 2 2 0 Amastin surface glycoprotein ABC2_membrane_2 PF12679.2 AEO54613.1 - 1.6 7.5 9.6 0.096 11.5 3.1 1.6 2 0 0 2 2 2 0 ABC-2 family transporter protein ATP1G1_PLM_MAT8 PF02038.11 AEO54613.1 - 8.4 5.4 6.2 7.9 5.5 0.1 2.9 3 0 0 3 3 3 0 ATP1G1/PLM/MAT8 family ACPS PF01648.15 AEO54614.1 - 1.1e-05 25.2 0.0 2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Peptidase_A22B PF04258.8 AEO54615.1 - 2.6e-49 168.2 2.5 1.3e-48 165.9 1.7 2.0 1 1 0 1 1 1 1 Signal peptide peptidase DUF4131 PF13567.1 AEO54615.1 - 0.0064 15.9 2.0 16 4.8 0.1 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF4131) Med31 PF05669.7 AEO54616.1 - 6.5e-37 125.3 0.3 7.4e-37 125.2 0.2 1.0 1 0 0 1 1 1 1 SOH1 TFIIS_C PF01096.13 AEO54617.1 - 9.8e-21 73.1 3.1 9.8e-21 73.1 2.2 2.5 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 AEO54617.1 - 4.8e-09 35.7 0.4 4.8e-09 35.7 0.3 2.4 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.2 AEO54617.1 - 0.00077 19.2 4.3 0.16 11.8 0.2 2.3 2 0 0 2 2 2 2 Transposase zinc-ribbon domain C1_4 PF07975.7 AEO54617.1 - 0.023 14.6 2.6 3 7.9 0.1 2.6 2 1 0 2 2 2 0 TFIIH C1-like domain Elf1 PF05129.8 AEO54617.1 - 0.15 11.7 4.0 1.8 8.2 0.1 2.6 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like DZR PF12773.2 AEO54617.1 - 0.2 11.5 4.8 1.1 9.0 0.1 2.5 2 1 0 2 2 2 0 Double zinc ribbon C1_3 PF07649.7 AEO54617.1 - 0.57 10.2 0.2 0.57 10.2 0.1 2.7 3 0 0 3 3 3 0 C1-like domain Zn_ribbon_recom PF13408.1 AEO54617.1 - 0.64 10.3 3.8 2.3 8.5 0.1 2.6 3 0 0 3 3 3 0 Recombinase zinc beta ribbon domain Baculo_LEF5_C PF11792.3 AEO54617.1 - 0.69 9.3 0.0 0.69 9.3 0.0 2.3 3 1 1 4 4 4 0 Baculoviridae late expression factor 5 C-terminal domain zinc_ribbon_2 PF13240.1 AEO54617.1 - 3.3 7.3 5.9 6.5 6.3 0.2 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zf-BED PF02892.10 AEO54617.1 - 4.5 7.1 6.4 5.6 6.7 0.1 3.2 3 1 1 4 4 4 0 BED zinc finger Ank_4 PF13637.1 AEO54618.1 - 1.2e-11 44.7 0.0 6.2e-06 26.5 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 AEO54618.1 - 2.9e-11 43.5 0.0 4.5e-10 39.7 0.0 2.4 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 AEO54618.1 - 5.6e-11 41.6 0.4 0.0019 17.9 0.0 4.0 4 1 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 AEO54618.1 - 6.2e-10 38.3 0.0 0.026 14.7 0.0 3.9 4 1 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 AEO54618.1 - 2.4e-08 33.9 0.1 0.18 12.0 0.0 4.1 2 1 2 4 4 4 2 Ankyrin repeats (many copies) HSP70 PF00012.15 AEO54619.1 - 1.9e-11 42.5 0.3 8.5e-10 37.1 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein zf-SAP30 PF13866.1 AEO54619.1 - 0.0036 16.9 0.1 0.008 15.8 0.1 1.5 1 0 0 1 1 1 1 SAP30 zinc-finger MreB_Mbl PF06723.8 AEO54619.1 - 0.023 13.3 0.1 0.13 10.8 0.0 1.9 2 0 0 2 2 2 0 MreB/Mbl protein Hexokinase_1 PF00349.16 AEO54620.1 - 8.8e-65 217.8 0.1 1.8e-64 216.9 0.0 1.5 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 AEO54620.1 - 1e-61 208.2 0.0 2e-61 207.3 0.0 1.5 1 1 0 1 1 1 1 Hexokinase Toxin_63 PF15541.1 AEO54620.1 - 0.026 14.4 0.0 0.066 13.1 0.0 1.6 1 0 0 1 1 1 0 Putative toxin 63 Acetyltransf_1 PF00583.19 AEO54621.1 - 7.3e-06 25.9 0.0 1.4e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AEO54621.1 - 0.12 12.5 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Sgf11 PF08209.6 AEO54622.1 - 0.66 9.3 7.2 0.066 12.5 1.8 1.7 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.1 AEO54622.1 - 2 8.1 8.1 0.12 12.0 0.9 2.2 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Pro_isomerase PF00160.16 AEO54623.1 - 4.9e-52 176.2 0.0 5.7e-52 176.0 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Myosin_head PF00063.16 AEO54624.1 - 8e-249 827.3 0.7 1.6e-248 826.2 0.0 1.9 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 AEO54624.1 - 1.8e-27 95.4 193.5 7.5e-26 90.1 85.9 3.6 2 2 0 2 2 2 2 Myosin tail Myosin_N PF02736.14 AEO54624.1 - 4.8e-06 26.1 0.2 1.2e-05 24.8 0.1 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Filament PF00038.16 AEO54624.1 - 0.00025 20.6 15.0 0.00025 20.6 10.4 9.7 2 2 7 9 9 9 5 Intermediate filament protein UDPG_MGDP_dh_N PF03721.9 AEO54624.1 - 0.00037 19.9 2.7 0.001 18.5 1.9 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AAA_19 PF13245.1 AEO54624.1 - 0.024 14.3 0.0 0.087 12.5 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 AEO54624.1 - 0.068 13.3 3.7 0.17 12.0 0.0 3.8 3 0 0 3 3 3 0 AAA domain zf-C3H1 PF10650.4 AEO54625.1 - 6.6e-09 35.0 2.1 1e-08 34.4 1.5 1.3 1 0 0 1 1 1 1 Putative zinc-finger domain IncA PF04156.9 AEO54625.1 - 0.2 11.2 5.1 0.81 9.2 3.6 2.0 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 AEO54625.1 - 0.3 10.1 3.1 0.74 8.8 2.2 1.6 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF972 PF06156.8 AEO54625.1 - 3 8.2 4.1 1.1 9.6 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) 4HBT_3 PF13622.1 AEO54626.1 - 4.6e-47 160.9 5.0 6.3e-47 160.4 3.5 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 AEO54626.1 - 2.5e-22 78.8 0.0 4.3e-11 42.5 0.0 4.0 3 1 0 3 3 3 3 Acyl-CoA thioesterase Retrotrans_gag PF03732.12 AEO54627.1 - 4.7e-08 33.0 0.9 4.7e-08 33.0 0.6 1.9 1 1 1 2 2 2 1 Retrotransposon gag protein Prefoldin_2 PF01920.15 AEO54627.1 - 0.015 15.0 1.1 0.015 15.0 0.7 2.4 2 1 0 2 2 2 0 Prefoldin subunit AUX_IAA PF02309.11 AEO54627.1 - 0.018 14.8 1.2 0.018 14.8 0.8 1.5 1 1 1 2 2 2 0 AUX/IAA family DUF3482 PF11981.3 AEO54628.1 - 0.53 9.4 2.2 0.57 9.3 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) TraT PF05818.7 AEO54628.1 - 0.6 9.4 3.3 0.73 9.2 2.3 1.1 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein zf-3CxxC PF13695.1 AEO54630.1 - 4.7e-25 87.6 0.1 7.4e-25 87.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding domain Oxysterol_BP PF01237.13 AEO54631.1 - 3.1e-129 430.5 0.0 1.3e-128 428.4 0.0 1.9 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_2 PF12796.2 AEO54631.1 - 1.7e-18 66.7 0.0 2.1e-12 47.1 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 AEO54631.1 - 7.6e-18 63.3 0.1 3.3e-07 29.7 0.0 4.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 AEO54631.1 - 4.7e-17 61.6 1.3 1.2e-09 38.0 0.2 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 AEO54631.1 - 1.6e-15 57.0 0.2 1.5e-08 34.9 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 AEO54631.1 - 8.4e-14 50.3 0.1 7.2e-06 25.7 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat PH PF00169.24 AEO54631.1 - 9e-13 48.3 0.4 2.4e-12 46.9 0.3 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 AEO54631.1 - 3.6e-10 40.0 1.0 1.5e-09 38.0 0.7 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 AEO54631.1 - 2.3e-07 30.8 0.7 5.9e-07 29.4 0.5 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain EST1_DNA_bind PF10373.4 AEO54632.1 - 5.3e-18 65.2 0.4 1.2e-17 64.0 0.3 1.7 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain DUF3226 PF11536.3 AEO54632.1 - 0.21 11.0 0.0 0.35 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3226) MFS_1 PF07690.11 AEO54633.1 - 1e-15 57.3 37.4 9.2e-10 37.7 17.8 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily ABC_tran PF00005.22 AEO54634.1 - 1e-52 178.0 0.0 5.2e-28 98.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 AEO54634.1 - 3.6e-32 111.8 30.9 1.2e-28 100.3 14.2 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 AEO54634.1 - 2.2e-12 46.7 2.1 3e-06 26.6 0.1 3.6 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 AEO54634.1 - 8.4e-11 42.1 0.5 0.00018 21.5 0.2 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 AEO54634.1 - 9.7e-11 42.1 0.1 0.016 15.1 0.0 3.8 4 0 0 4 4 4 3 AAA domain AAA_29 PF13555.1 AEO54634.1 - 2e-09 36.8 0.2 0.0013 18.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_33 PF13671.1 AEO54634.1 - 7.8e-07 29.0 0.0 0.0026 17.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 AEO54634.1 - 1.3e-06 28.8 0.1 0.052 14.0 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein AAA_22 PF13401.1 AEO54634.1 - 2.6e-06 27.5 0.7 0.054 13.6 0.0 3.3 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 AEO54634.1 - 3.5e-06 26.9 0.0 0.044 13.7 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 AEO54634.1 - 5e-06 26.1 0.1 0.11 12.0 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_25 PF13481.1 AEO54634.1 - 6.9e-06 25.5 0.5 0.042 13.2 0.0 3.1 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 AEO54634.1 - 9.6e-06 24.8 0.1 0.052 12.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 RNA_helicase PF00910.17 AEO54634.1 - 1.1e-05 25.4 0.3 0.17 12.0 0.0 3.8 4 0 0 4 4 3 1 RNA helicase AAA_17 PF13207.1 AEO54634.1 - 1.4e-05 25.9 1.0 0.26 12.1 0.1 2.8 2 2 0 2 2 2 2 AAA domain AAA_10 PF12846.2 AEO54634.1 - 2e-05 24.2 1.8 0.013 14.9 0.2 2.5 2 0 0 2 2 2 2 AAA-like domain MobB PF03205.9 AEO54634.1 - 0.0001 22.0 0.3 0.27 10.9 0.0 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 AEO54634.1 - 0.00021 21.1 3.1 0.077 12.8 0.2 2.4 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_23 PF13476.1 AEO54634.1 - 0.00072 19.9 0.9 0.24 11.6 0.1 2.3 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.22 AEO54634.1 - 0.001 18.5 0.0 0.34 10.3 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA PF00004.24 AEO54634.1 - 0.0012 18.9 0.4 0.94 9.6 0.0 3.7 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 AEO54634.1 - 0.0013 19.0 0.0 1.7 8.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 AEO54634.1 - 0.0014 17.5 0.0 0.21 10.4 0.0 2.7 2 1 0 2 2 2 1 NB-ARC domain Dynamin_N PF00350.18 AEO54634.1 - 0.0024 17.7 0.9 0.095 12.5 0.0 2.4 2 0 0 2 2 2 1 Dynamin family NACHT PF05729.7 AEO54634.1 - 0.0024 17.5 0.1 0.34 10.5 0.0 2.8 2 0 0 2 2 2 1 NACHT domain Arch_ATPase PF01637.13 AEO54634.1 - 0.0032 17.2 0.1 0.049 13.3 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase NTPase_1 PF03266.10 AEO54634.1 - 0.0046 16.6 0.4 4.3 7.0 0.0 3.0 3 0 0 3 3 2 0 NTPase Zeta_toxin PF06414.7 AEO54634.1 - 0.0061 15.6 0.0 0.46 9.5 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin DUF815 PF05673.8 AEO54634.1 - 0.0077 15.1 0.9 2.9 6.7 0.0 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF815) T2SE PF00437.15 AEO54634.1 - 0.009 14.9 0.0 0.078 11.8 0.0 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein SbcCD_C PF13558.1 AEO54634.1 - 0.0099 15.7 0.2 3.9 7.4 0.0 2.9 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.9 AEO54634.1 - 0.015 15.0 0.8 12 5.6 0.0 3.8 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) cobW PF02492.14 AEO54634.1 - 0.016 14.6 1.3 0.54 9.6 0.1 2.9 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 AEO54634.1 - 0.024 14.2 1.1 0.88 9.1 0.0 3.0 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.1 AEO54634.1 - 0.025 14.4 0.1 2.3 8.1 0.0 3.5 4 0 0 4 4 3 0 AAA domain TrwB_AAD_bind PF10412.4 AEO54634.1 - 0.043 12.4 0.1 0.65 8.5 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ATP_bind_1 PF03029.12 AEO54634.1 - 0.043 13.3 0.6 2.7 7.4 0.1 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF3987 PF13148.1 AEO54634.1 - 0.045 12.3 0.1 1.1 7.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Septin PF00735.13 AEO54634.1 - 0.065 12.2 0.0 5.4 5.9 0.0 2.3 2 0 0 2 2 2 0 Septin PIF1 PF05970.9 AEO54634.1 - 0.092 11.6 0.1 0.29 10.0 0.0 1.8 2 0 0 2 2 1 0 PIF1-like helicase ArgK PF03308.11 AEO54634.1 - 0.1 11.3 0.2 7.3 5.2 0.0 2.3 2 0 0 2 2 2 0 ArgK protein KaiC PF06745.8 AEO54634.1 - 0.12 11.4 1.1 3.4 6.7 0.0 2.7 3 0 0 3 3 3 0 KaiC ATP-synt_ab PF00006.20 AEO54634.1 - 0.25 10.7 1.1 9.5 5.6 0.1 2.8 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_15 PF13175.1 AEO54634.1 - 0.78 8.7 0.0 2.7 6.9 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain Gly_transf_sug PF04488.10 AEO54638.1 - 2.3e-12 47.1 0.0 4.7e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif AMP-binding PF00501.23 AEO54639.1 - 6.4e-88 294.9 0.0 8.8e-88 294.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 AEO54639.1 - 2.9e-16 60.1 0.2 7.7e-16 58.8 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain adh_short PF00106.20 AEO54640.1 - 1.3e-34 119.5 1.1 1.6e-34 119.2 0.8 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO54640.1 - 1.5e-12 47.5 0.2 2.1e-12 47.0 0.2 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 AEO54640.1 - 1.6e-12 47.7 0.0 2.1e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 AEO54640.1 - 8e-05 22.1 0.1 0.00017 21.0 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 AEO54640.1 - 0.0036 16.9 0.2 0.0046 16.6 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 AEO54640.1 - 0.0045 16.0 0.2 0.0092 15.0 0.0 1.6 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DFP PF04127.10 AEO54640.1 - 0.019 14.6 0.1 0.027 14.0 0.0 1.3 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein RmlD_sub_bind PF04321.12 AEO54640.1 - 0.024 13.5 0.0 0.031 13.1 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain 3Beta_HSD PF01073.14 AEO54640.1 - 0.038 12.7 0.0 0.044 12.4 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family AdoHcyase_NAD PF00670.16 AEO54640.1 - 0.045 13.5 0.9 0.1 12.4 0.6 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Eno-Rase_NADH_b PF12242.3 AEO54640.1 - 0.058 13.1 3.8 0.13 12.0 2.6 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 AEO54640.1 - 0.08 12.9 2.0 0.16 11.9 1.3 1.6 1 1 0 1 1 1 0 NADH(P)-binding 2-Hacid_dh_C PF02826.14 AEO54640.1 - 0.12 11.4 0.1 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NmrA PF05368.8 AEO54640.1 - 0.16 11.2 0.9 1.4 8.0 0.4 2.0 2 0 0 2 2 2 0 NmrA-like family ThiF PF00899.16 AEO54641.1 - 4e-35 120.5 0.1 1.3e-34 118.9 0.0 1.9 2 0 0 2 2 2 1 ThiF family Glyco_hydro_17 PF00332.13 AEO54641.1 - 0.013 14.5 0.0 0.023 13.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 Saccharop_dh PF03435.13 AEO54641.1 - 0.022 13.7 0.0 0.065 12.2 0.0 1.7 1 1 0 1 1 1 0 Saccharopine dehydrogenase TrkA_N PF02254.13 AEO54641.1 - 0.03 14.3 0.2 0.15 12.0 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain RTC PF01137.16 AEO54642.1 - 5.6e-40 136.5 0.0 1.2e-39 135.4 0.0 1.5 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase Transport_MerF PF11431.3 AEO54642.1 - 0.051 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Membrane transport protein MerF Elongin_A PF06881.6 AEO54643.1 - 0.024 15.0 0.4 0.028 14.8 0.3 1.1 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF3416 PF11896.3 AEO54643.1 - 0.13 12.2 1.6 0.14 12.1 1.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3416) QRPTase_C PF01729.14 AEO54644.1 - 1.1e-53 181.2 0.1 1.3e-53 180.9 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 AEO54644.1 - 2.1e-23 81.9 0.0 5.4e-23 80.6 0.0 1.7 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain IGPS PF00218.16 AEO54644.1 - 0.026 13.5 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase RCC1 PF00415.13 AEO54645.1 - 4.1e-63 209.4 0.0 1.4e-13 50.7 0.1 7.8 7 2 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 AEO54645.1 - 8e-37 124.0 19.0 9.5e-08 31.4 0.2 6.5 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.6 AEO54645.1 - 0.026 13.7 0.1 7.2 5.7 0.0 2.9 3 0 0 3 3 3 0 TUP1-like enhancer of split DUF1811 PF08838.5 AEO54645.1 - 0.21 11.5 0.0 5.9 6.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1811) DUF619 PF04768.8 AEO54646.1 - 1.1e-51 174.6 0.0 1.9e-51 173.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 AEO54646.1 - 1e-29 103.2 0.0 3.6e-29 101.5 0.0 2.0 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 AEO54646.1 - 3.2e-29 102.1 0.0 5.8e-29 101.3 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.15 AEO54646.1 - 0.043 13.7 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Synaptobrevin PF00957.16 AEO54647.1 - 4.2e-26 90.3 2.0 4.8e-26 90.1 1.4 1.0 1 0 0 1 1 1 1 Synaptobrevin GP41 PF00517.12 AEO54647.1 - 0.0018 17.8 0.1 0.0022 17.6 0.1 1.0 1 0 0 1 1 1 1 Retroviral envelope protein Spc7 PF08317.6 AEO54647.1 - 0.014 14.0 2.0 0.017 13.8 1.4 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein EMP24_GP25L PF01105.19 AEO54647.1 - 0.029 14.0 0.3 0.033 13.9 0.2 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Sec8_exocyst PF04048.9 AEO54647.1 - 0.031 13.8 0.5 0.041 13.5 0.4 1.2 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain YukC PF10140.4 AEO54647.1 - 0.033 12.7 0.0 0.038 12.5 0.0 1.0 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Snapin_Pallidin PF14712.1 AEO54647.1 - 0.038 14.2 0.5 0.053 13.8 0.3 1.2 1 0 0 1 1 1 0 Snapin/Pallidin OmpH PF03938.9 AEO54647.1 - 0.051 13.5 0.7 0.063 13.2 0.5 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Laminin_II PF06009.7 AEO54647.1 - 0.052 13.2 1.1 0.069 12.9 0.8 1.1 1 0 0 1 1 1 0 Laminin Domain II DUF2205 PF10224.4 AEO54647.1 - 0.068 12.7 1.3 0.1 12.1 0.9 1.2 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) FadA PF09403.5 AEO54647.1 - 0.083 12.9 2.6 0.12 12.4 1.8 1.3 1 0 0 1 1 1 0 Adhesion protein FadA DUF2207 PF09972.4 AEO54647.1 - 0.095 11.2 0.1 0.12 10.9 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Radical_SAM PF04055.16 AEO54648.1 - 1.1e-17 64.7 0.0 1.6e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Ribosomal_S14 PF00253.16 AEO54649.1 - 4.8e-18 64.2 1.3 6e-18 63.9 0.4 1.5 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e Arb2 PF09757.4 AEO54650.1 - 1.4e-19 70.2 0.0 3e-19 69.1 0.0 1.5 2 0 0 2 2 2 1 Arb2 domain HA PF03457.9 AEO54651.1 - 8.7 6.5 8.8 3.8 7.6 0.6 3.3 3 0 0 3 3 3 0 Helicase associated domain Herpes_LMP1 PF05297.6 AEO54652.1 - 0.0095 14.9 0.0 0.013 14.4 0.0 1.1 1 0 0 1 1 1 1 Herpesvirus latent membrane protein 1 (LMP1) DUF4191 PF13829.1 AEO54652.1 - 0.015 14.4 0.1 0.023 13.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF3465 PF11948.3 AEO54652.1 - 0.041 13.6 0.0 0.071 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3465) DUF1398 PF07166.6 AEO54652.1 - 0.076 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1398) WD40 PF00400.27 AEO54653.1 - 8.1e-16 57.2 16.7 1.7e-06 27.6 0.5 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat Zn_clus PF00172.13 AEO54655.1 - 0.00037 20.3 9.6 0.00056 19.7 6.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PFL PF02901.10 AEO54655.1 - 0.25 9.7 1.3 0.37 9.1 0.9 1.1 1 0 0 1 1 1 0 Pyruvate formate lyase CENP-B_dimeris PF09026.5 AEO54655.1 - 0.31 11.2 6.7 0.65 10.2 4.7 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RRM_1 PF00076.17 AEO54656.1 - 7.2e-19 67.1 0.0 2.3e-12 46.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO54656.1 - 7.5e-12 45.0 0.0 3.2e-06 27.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO54656.1 - 0.16 11.8 0.0 19 5.2 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cut8_N PF14482.1 AEO54658.1 - 0.14 12.2 0.9 0.17 11.9 0.6 1.3 1 0 0 1 1 1 0 Cut8 proteasome-binding domain adh_short PF00106.20 AEO54659.1 - 6.3e-21 75.0 6.7 8.2e-21 74.6 0.6 2.9 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 AEO54659.1 - 1.4e-08 34.6 4.7 1.9e-06 27.6 0.1 3.0 3 1 1 4 4 4 2 KR domain adh_short_C2 PF13561.1 AEO54659.1 - 6.6e-05 22.7 0.0 0.0095 15.7 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 AEO54659.1 - 0.11 11.8 0.0 0.25 10.7 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Semialdhyde_dhC PF02774.13 AEO54660.1 - 3.1e-39 134.7 0.0 4.4e-39 134.2 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 AEO54660.1 - 4.1e-30 104.5 0.0 1.5e-29 102.7 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 AEO54660.1 - 0.0038 17.1 0.0 0.0071 16.2 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.17 AEO54660.1 - 0.012 16.1 0.0 0.03 14.8 0.0 1.7 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold DXP_reductoisom PF02670.11 AEO54660.1 - 0.11 13.0 0.0 0.32 11.5 0.0 1.8 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase RhoGAP PF00620.22 AEO54661.1 - 1.4e-48 164.4 0.2 4.5e-48 162.7 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 AEO54661.1 - 3.2e-17 62.4 0.6 7.9e-17 61.2 0.4 1.7 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Ish1 PF10281.4 AEO54661.1 - 0.042 13.9 0.1 0.17 12.0 0.0 2.1 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein TACC PF05010.9 AEO54661.1 - 1.4 8.6 9.8 0.089 12.5 2.2 1.9 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC) TPR_MLP1_2 PF07926.7 AEO54661.1 - 1.7 8.4 13.6 0.89 9.3 4.7 2.8 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF1620 PF07774.8 AEO54662.1 - 1.7e-70 236.7 0.0 2.4e-70 236.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 AEO54662.1 - 5.7e-14 52.1 14.0 4.8e-13 49.1 3.8 3.3 3 1 0 3 3 3 2 PQQ-like domain PQQ PF01011.16 AEO54662.1 - 4.8e-10 38.4 1.2 0.057 12.9 0.0 5.8 7 0 0 7 7 7 3 PQQ enzyme repeat PQQ_3 PF13570.1 AEO54662.1 - 0.32 11.3 7.5 5.2 7.4 0.2 4.8 5 1 0 5 5 5 0 PQQ-like domain LRR_4 PF12799.2 AEO54663.1 - 7.2e-07 28.6 2.4 2.3e-06 27.1 0.4 2.5 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AEO54663.1 - 1.8e-06 27.6 2.8 3.1e-05 23.6 1.8 2.3 2 0 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.28 AEO54663.1 - 8.2e-05 22.1 4.4 4.9 7.5 0.0 4.4 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 AEO54663.1 - 0.019 15.0 3.1 30 5.4 0.0 4.2 4 0 0 4 4 4 0 Leucine rich repeat Peptidase_S8 PF00082.17 AEO54665.1 - 0.011 14.8 0.1 0.024 13.7 0.1 1.5 1 1 0 1 1 1 0 Subtilase family Ank_3 PF13606.1 AEO54666.1 - 0.075 13.3 0.1 1.4 9.4 0.0 2.9 3 0 0 3 3 3 0 Ankyrin repeat Ank PF00023.25 AEO54666.1 - 0.091 12.6 0.6 0.7 9.8 0.0 2.8 3 1 1 4 4 4 0 Ankyrin repeat Ank_4 PF13637.1 AEO54666.1 - 0.1 13.1 0.0 5.3 7.6 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_2 PF12796.2 AEO54666.1 - 0.15 12.3 0.1 2.2 8.6 0.1 2.5 1 1 1 2 2 2 0 Ankyrin repeats (3 copies) Ank_5 PF13857.1 AEO54666.1 - 0.16 12.2 0.5 4.1 7.7 0.0 3.2 4 0 0 4 4 4 0 Ankyrin repeats (many copies) ZZ PF00569.12 AEO54667.1 - 8.3e-05 22.0 3.0 0.00017 21.0 2.1 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type tRNA-synt_2 PF00152.15 AEO54668.1 - 1.2e-72 244.5 0.0 1.5e-72 244.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 AEO54668.1 - 0.00048 19.9 0.0 0.00091 19.0 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain NARP1 PF12569.3 AEO54668.1 - 0.16 10.7 6.3 0.23 10.1 4.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SIP1 PF04938.7 AEO54669.1 - 4.8e-06 26.0 0.0 0.0091 15.3 0.0 3.2 3 0 0 3 3 3 3 Survival motor neuron (SMN) interacting protein 1 (SIP1) RNR_inhib PF08591.5 AEO54670.1 - 6.8e-24 84.6 0.1 2e-23 83.1 0.1 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase inhibitor Ribosomal_S27e PF01667.12 AEO54671.1 - 2.2e-28 97.5 7.4 2.7e-28 97.2 5.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 AEO54671.1 - 0.0079 16.0 1.3 0.0089 15.8 0.9 1.2 1 0 0 1 1 1 1 IBR domain TF_Zn_Ribbon PF08271.7 AEO54671.1 - 0.29 10.4 3.3 0.41 10.0 2.3 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding Phosducin PF02114.11 AEO54672.1 - 3.1e-11 42.4 0.0 4.4e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.15 AEO54672.1 - 0.1 12.2 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Raptor_N PF14538.1 AEO54673.1 - 4.1e-65 218.3 0.0 9.3e-65 217.1 0.0 1.7 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 AEO54673.1 - 1.5e-07 30.9 0.1 1.1 9.2 0.0 5.9 5 0 0 5 5 5 2 WD domain, G-beta repeat BBS2_Mid PF14783.1 AEO54673.1 - 0.00011 21.8 0.2 0.032 13.9 0.1 2.6 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, middle region HEAT PF02985.17 AEO54673.1 - 0.00027 20.7 0.4 2.7 8.3 0.0 4.9 5 0 0 5 5 5 1 HEAT repeat Atx10homo_assoc PF09759.4 AEO54673.1 - 0.14 11.8 0.1 0.46 10.2 0.0 1.8 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain Cnd1 PF12717.2 AEO54673.1 - 0.17 11.7 0.3 13 5.5 0.1 3.2 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Kelch_4 PF13418.1 AEO54674.1 - 4.1e-41 138.5 12.2 8.3e-09 35.0 1.0 6.7 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 AEO54674.1 - 2.6e-35 119.8 5.7 9.2e-08 31.8 0.1 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.1 AEO54674.1 - 5.3e-34 115.6 17.1 5.8e-08 32.6 0.2 7.2 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_1 PF01344.20 AEO54674.1 - 1.6e-33 113.9 3.3 2.2e-11 43.1 0.1 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 AEO54674.1 - 5e-33 111.8 7.6 1.1e-11 44.3 0.7 6.4 5 1 1 6 6 6 6 Kelch motif Kelch_2 PF07646.10 AEO54674.1 - 7.3e-22 76.2 6.8 1.3e-07 31.0 0.2 6.7 6 1 0 6 6 6 5 Kelch motif Mpv17_PMP22 PF04117.7 AEO54675.1 - 1.2e-14 53.6 0.5 1.2e-14 53.6 0.3 1.9 2 0 0 2 2 2 1 Mpv17 / PMP22 family YIF1 PF03878.10 AEO54676.1 - 2e-75 253.0 2.6 2.4e-75 252.7 1.8 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 AEO54676.1 - 0.00021 20.8 5.5 0.00023 20.6 3.2 1.5 2 0 0 2 2 2 1 Yip1 domain SRP-alpha_N PF04086.8 AEO54677.1 - 3.5e-78 262.7 0.0 5e-78 262.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.17 AEO54677.1 - 9.7e-53 178.5 0.2 1.8e-52 177.6 0.2 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.14 AEO54677.1 - 3e-07 30.4 0.4 2e-06 27.8 0.2 2.4 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain ArgK PF03308.11 AEO54677.1 - 1.6e-05 23.8 0.0 3.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 ArgK protein CbiA PF01656.18 AEO54677.1 - 0.001 18.5 0.2 0.0036 16.7 0.1 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 AEO54677.1 - 0.016 14.8 0.1 0.042 13.5 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 AEO54677.1 - 0.04 14.2 0.0 0.19 12.0 0.0 2.1 2 0 0 2 2 2 0 ABC transporter MMR_HSR1 PF01926.18 AEO54677.1 - 0.046 13.6 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.1 AEO54677.1 - 0.048 13.6 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain PI3_PI4_kinase PF00454.22 AEO54678.1 - 8.9e-51 172.6 0.0 1.7e-50 171.7 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 AEO54678.1 - 2.2e-45 155.2 0.3 3.4e-45 154.5 0.2 1.3 1 0 0 1 1 1 1 FAT domain UME PF08064.8 AEO54678.1 - 6.5e-31 106.4 0.0 4.2e-30 103.8 0.0 2.6 1 0 0 1 1 1 1 UME (NUC010) domain FATC PF02260.15 AEO54678.1 - 7.8e-15 54.0 0.0 1.9e-14 52.7 0.0 1.7 1 0 0 1 1 1 1 FATC domain TPR_14 PF13428.1 AEO54678.1 - 0.00013 22.3 5.2 0.11 13.1 0.1 5.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 AEO54678.1 - 0.00074 19.8 1.0 0.4 11.0 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 AEO54678.1 - 0.0023 18.5 3.9 1.4 9.7 0.1 3.8 2 1 0 2 2 2 2 Tetratricopeptide repeat zf-PARP PF00645.13 AEO54679.1 - 2.7e-22 78.7 0.8 5.1e-22 77.9 0.6 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Med17 PF10156.4 AEO54681.1 - 1.2e-93 313.9 0.0 5.6e-93 311.7 0.0 1.8 2 0 0 2 2 2 1 Subunit 17 of Mediator complex PFK PF00365.15 AEO54682.1 - 2.8e-164 544.9 0.4 4.1e-120 400.0 1.1 2.3 2 0 0 2 2 2 2 Phosphofructokinase UVR PF02151.14 AEO54682.1 - 0.0053 16.2 0.2 0.016 14.7 0.1 1.7 1 0 0 1 1 1 1 UvrB/uvrC motif SKG6 PF08693.5 AEO54683.1 - 0.043 13.1 0.5 0.11 11.8 0.3 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SNF2_N PF00176.18 AEO54684.1 - 2.2e-67 226.9 0.2 3.6e-67 226.2 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AEO54684.1 - 7.9e-13 48.0 0.0 1.6e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 AEO54684.1 - 1e-09 37.8 2.3 1.9e-09 37.0 1.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AEO54684.1 - 1e-07 31.6 4.3 2.2e-07 30.5 3.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 AEO54684.1 - 2e-07 30.9 4.3 4.2e-07 29.8 3.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AEO54684.1 - 2e-07 30.5 4.3 3.8e-07 29.6 3.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO54684.1 - 2.2e-06 27.2 3.5 4.3e-06 26.3 2.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 AEO54684.1 - 1.6e-05 24.7 5.3 3.7e-05 23.4 3.7 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING DEAD PF00270.24 AEO54684.1 - 0.00057 19.4 0.1 0.0023 17.4 0.0 2.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase zf-RING_UBOX PF13445.1 AEO54684.1 - 0.0011 18.6 2.2 0.0029 17.2 1.5 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-MIZ PF02891.15 AEO54684.1 - 0.0025 17.2 1.4 0.0061 16.0 0.9 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-RING_4 PF14570.1 AEO54684.1 - 0.044 13.3 4.7 0.16 11.5 3.4 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain DZR PF12773.2 AEO54684.1 - 1.8 8.4 5.7 1.8 8.4 2.4 2.1 2 0 0 2 2 2 0 Double zinc ribbon Phosphodiest PF01663.17 AEO54685.1 - 1.3e-93 314.2 0.3 1.7e-93 313.8 0.2 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 AEO54685.1 - 0.00011 21.5 0.2 0.012 14.8 0.1 2.3 1 1 0 1 1 1 1 Sulfatase YwiC PF14256.1 AEO54685.1 - 0.042 13.9 0.2 0.077 13.0 0.2 1.3 1 0 0 1 1 1 0 YwiC-like protein PglZ PF08665.7 AEO54685.1 - 0.042 13.5 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 PglZ domain DUF948 PF06103.6 AEO54685.1 - 0.23 11.3 0.6 0.71 9.7 0.2 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Acetyltransf_9 PF13527.1 AEO54686.1 - 2e-06 27.6 0.1 3.8e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 AEO54686.1 - 3.1e-06 27.2 0.0 5.6e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 AEO54686.1 - 2.9e-05 24.0 0.0 0.005 16.8 0.0 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 AEO54686.1 - 0.00057 19.9 0.1 0.0029 17.7 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 AEO54686.1 - 0.064 13.1 0.2 0.46 10.4 0.0 2.3 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase GnRH PF00446.12 AEO54686.1 - 9.7 6.3 8.4 13 6.0 1.5 2.6 2 0 0 2 2 2 0 Gonadotropin-releasing hormone Ribosomal_L14e PF01929.12 AEO54687.1 - 6.2e-29 100.1 2.8 8.7e-29 99.7 1.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 NAC PF01849.13 AEO54688.1 - 2.1e-26 91.2 0.3 3.2e-25 87.4 0.0 2.3 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 AEO54688.1 - 0.00047 19.9 0.2 0.0011 18.7 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain DUF1373 PF07117.6 AEO54688.1 - 0.34 10.5 1.5 0.73 9.5 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1373) Ribosomal_S13 PF00416.17 AEO54688.1 - 0.42 11.0 2.2 0.61 10.5 0.2 2.0 2 1 1 3 3 3 0 Ribosomal protein S13/S18 FAM176 PF14851.1 AEO54688.1 - 3.1 7.4 11.3 6.4 6.4 1.0 2.2 2 0 0 2 2 2 0 FAM176 family SpoIIIAH PF12685.2 AEO54688.1 - 6.6 6.1 15.4 0.42 10.0 5.4 2.0 2 0 0 2 2 2 0 SpoIIIAH-like protein Mt_ATP-synt_D PF05873.7 AEO54689.1 - 5.2e-19 68.4 1.8 6.6e-19 68.1 1.2 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) TRADD_N PF09034.5 AEO54689.1 - 0.093 12.7 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 TRADD, N-terminal domain T2SM_b PF10741.4 AEO54689.1 - 0.1 12.2 0.0 0.25 10.9 0.0 1.7 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein M subtype b XhlA PF10779.4 AEO54689.1 - 1 9.3 3.9 2.3 8.1 2.7 1.6 1 0 0 1 1 1 0 Haemolysin XhlA COX16 PF14138.1 AEO54690.1 - 6.7e-34 115.8 0.4 9.6e-34 115.4 0.1 1.4 2 0 0 2 2 2 1 Cytochrome c oxidase assembly protein COX16 Amidohydro_1 PF01979.15 AEO54692.1 - 2e-14 54.0 1.5 5.4e-08 32.8 0.0 2.7 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 AEO54692.1 - 2.6e-12 47.3 9.3 4.5e-12 46.5 6.4 1.5 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 AEO54692.1 - 1.5e-10 40.6 0.5 5.4e-09 35.7 0.0 2.5 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 AEO54692.1 - 2.5e-05 23.6 2.1 0.0061 15.8 0.1 2.7 2 0 0 2 2 2 2 Amidohydrolase family ATG16 PF08614.6 AEO54693.1 - 0.43 10.3 6.0 0.48 10.2 4.1 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF1687 PF07955.6 AEO54694.1 - 1.9e-20 73.1 0.2 5.7e-20 71.6 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) DUF3450 PF11932.3 AEO54694.1 - 0.018 14.3 0.7 0.023 13.9 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ArsC PF03960.10 AEO54694.1 - 0.036 14.1 0.0 0.11 12.5 0.0 1.9 1 1 0 1 1 1 0 ArsC family RRM_6 PF14259.1 AEO54695.1 - 4.8e-05 23.2 0.0 9.8e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AEO54695.1 - 0.038 13.6 0.0 0.082 12.5 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO54695.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sel1 PF08238.7 AEO54696.1 - 1.1e-44 149.8 24.1 2.7e-07 30.9 0.0 7.7 7 0 0 7 7 7 7 Sel1 repeat TPR_17 PF13431.1 AEO54696.1 - 0.0067 16.5 0.1 3.5 8.0 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 AEO54696.1 - 0.0068 17.0 14.2 2.3 8.9 0.0 5.2 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_20 PF14561.1 AEO54696.1 - 0.081 13.0 1.1 0.64 10.1 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 AEO54696.1 - 0.11 13.1 16.5 0.37 11.5 0.2 5.9 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 AEO54696.1 - 0.46 11.0 7.5 0.99 10.0 0.0 4.9 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 AEO54696.1 - 1.1 9.5 9.8 22 5.4 0.1 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat CBP4 PF07960.6 AEO54697.1 - 6e-40 135.8 1.8 7.3e-40 135.5 1.3 1.0 1 0 0 1 1 1 1 CBP4 DUF2852 PF11014.3 AEO54697.1 - 0.016 15.1 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) DUF1491 PF07372.7 AEO54697.1 - 0.077 12.9 1.9 2.2 8.2 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1491) NAC PF01849.13 AEO54698.1 - 1.2e-22 79.2 0.5 4.1e-22 77.4 0.2 1.9 2 0 0 2 2 2 1 NAC domain A_deamin PF02137.13 AEO54699.1 - 1.9e-55 188.5 0.0 2.2e-55 188.3 0.0 1.0 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain DUF605 PF04652.11 AEO54699.1 - 8.5 5.6 8.7 11 5.2 6.0 1.1 1 0 0 1 1 1 0 Vta1 like Ribosomal_L24e PF01246.15 AEO54700.1 - 5.8e-31 106.1 0.3 5.8e-31 106.1 0.2 1.9 2 0 0 2 2 2 1 Ribosomal protein L24e Redoxin PF08534.5 AEO54701.1 - 1.4e-37 128.4 0.0 1.6e-37 128.3 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 AEO54701.1 - 1.8e-10 40.5 0.0 2.2e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DUF1348 PF07080.6 AEO54702.1 - 2.6e-58 195.9 8.5 3.1e-58 195.6 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.2 AEO54702.1 - 1.9e-07 31.4 1.8 2.6e-07 30.9 1.2 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 AEO54702.1 - 5.1e-06 26.6 0.5 8e-06 26.0 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL PF07366.7 AEO54702.1 - 0.064 12.8 0.2 0.1 12.2 0.1 1.4 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase RGS PF00615.14 AEO54703.1 - 7.2e-07 29.3 0.4 1.1e-05 25.5 0.3 2.1 1 1 0 1 1 1 1 Regulator of G protein signaling domain Claudin_2 PF13903.1 AEO54703.1 - 0.036 13.7 1.1 0.2 11.3 0.6 2.0 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Fumble PF03630.9 AEO54704.1 - 2.6e-129 430.9 0.0 2.4e-128 427.7 0.0 2.1 1 1 0 1 1 1 1 Fumble MPC PF03650.8 AEO54705.1 - 1.7e-41 140.8 0.7 2.4e-41 140.4 0.5 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) L51_S25_CI-B8 PF05047.11 AEO54706.1 - 2.4e-08 33.5 0.1 3.2e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Abhydrolase_6 PF12697.2 AEO54708.1 - 2.7e-18 66.6 12.5 1.3e-17 64.4 8.7 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO54708.1 - 1.4e-09 37.8 1.5 4.8e-09 36.1 1.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 AEO54708.1 - 1.4e-05 24.8 0.0 4.4e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 AEO54708.1 - 0.0013 18.3 0.5 0.059 12.9 0.3 2.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 AEO54708.1 - 0.0017 17.6 0.0 0.0046 16.2 0.0 1.7 1 0 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.6 AEO54708.1 - 0.019 14.6 0.3 1.5 8.4 0.2 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Lipase_3 PF01764.20 AEO54708.1 - 0.23 11.0 1.7 0.44 10.1 1.2 1.4 1 0 0 1 1 1 0 Lipase (class 3) RNase_PH PF01138.16 AEO54709.1 - 1.4e-15 57.7 0.0 3.1e-14 53.4 0.0 2.5 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 AEO54709.1 - 0.011 15.6 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 DUF4129 PF13559.1 AEO54709.1 - 7.6 6.5 7.3 21 5.1 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4129) Nucleoplasmin PF03066.10 AEO54709.1 - 8.4 5.8 8.5 17 4.9 5.9 1.4 1 0 0 1 1 1 0 Nucleoplasmin GDI PF00996.13 AEO54710.1 - 8.9e-38 129.7 0.0 1.7e-37 128.8 0.0 1.3 1 1 0 1 1 1 1 GDP dissociation inhibitor Rad21_Rec8 PF04824.11 AEO54711.1 - 6.6e-08 31.6 0.1 1.7e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ALO PF04030.9 AEO54712.1 - 5.9e-95 317.7 0.6 7.6e-95 317.3 0.4 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 AEO54712.1 - 2.5e-30 104.7 0.0 3.7e-30 104.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain BTB PF00651.26 AEO54713.1 - 3e-16 59.3 0.2 8.9e-14 51.4 0.2 3.0 3 0 0 3 3 3 2 BTB/POZ domain DUF2360 PF10152.4 AEO54713.1 - 0.51 10.6 2.1 0.33 11.2 0.1 1.8 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF3597 PF12200.3 AEO54713.1 - 2.9 8.3 7.2 1.4 9.3 0.5 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3597) Pkinase PF00069.20 AEO54714.1 - 2.3e-59 200.6 0.0 3.8e-59 199.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO54714.1 - 5.2e-37 127.3 0.0 3e-26 92.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 AEO54714.1 - 0.00023 20.2 0.0 0.00041 19.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like NCA2 PF08637.5 AEO54714.1 - 0.0011 17.9 0.1 0.0036 16.2 0.0 1.8 2 0 0 2 2 2 1 ATP synthase regulation protein NCA2 HOOK PF05622.7 AEO54714.1 - 0.0013 16.6 7.6 0.0022 15.8 5.3 1.2 1 0 0 1 1 1 1 HOOK protein DUF607 PF04678.8 AEO54714.1 - 0.05 13.5 0.4 0.13 12.2 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF607 APH PF01636.18 AEO54714.1 - 0.071 12.8 0.7 0.21 11.2 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family zf-C2H2 PF00096.21 AEO54715.1 - 3.9e-09 36.3 11.0 0.00041 20.5 1.2 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 AEO54715.1 - 7.6e-07 29.1 9.4 9.3e-07 28.8 0.6 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 AEO54715.1 - 3.1e-05 23.9 9.1 0.007 16.6 0.6 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 AEO54715.1 - 0.018 15.2 3.4 0.041 14.1 1.0 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Dicty_CAD PF05720.7 AEO54715.1 - 0.061 12.9 0.1 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Cell-cell adhesion domain zf-C2H2_jaz PF12171.3 AEO54715.1 - 0.072 13.2 0.7 0.072 13.2 0.5 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 AEO54715.1 - 2.5 7.9 5.8 14 5.5 0.4 2.5 1 1 1 2 2 2 0 BED zinc finger Lipase_GDSL_2 PF13472.1 AEO54717.1 - 2.1e-10 41.0 0.5 4.9e-10 39.8 0.3 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 AEO54717.1 - 5.4e-07 29.6 3.4 4e-06 26.8 2.4 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 AEO54717.1 - 0.03 14.0 0.0 7.3 6.2 0.0 2.2 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family DUF2365 PF10157.4 AEO54718.1 - 0.0029 17.5 0.1 0.004 17.0 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2365) SMP_2 PF10144.4 AEO54718.1 - 0.018 14.1 0.1 0.023 13.8 0.1 1.2 1 0 0 1 1 1 0 Bacterial virulence factor haemolysin Fzo_mitofusin PF04799.8 AEO54718.1 - 0.14 11.5 0.3 0.36 10.2 0.1 1.6 1 1 0 1 1 1 0 fzo-like conserved region Rnk_N PF14760.1 AEO54718.1 - 0.65 10.1 4.0 2.5 8.2 2.2 2.3 2 0 0 2 2 2 0 Rnk N-terminus PHD PF00628.24 AEO54719.1 - 3.7e-12 45.7 7.6 3.7e-12 45.7 5.3 2.4 3 0 0 3 3 3 1 PHD-finger TBCA PF02970.11 AEO54719.1 - 0.22 11.6 1.1 0.34 11.0 0.1 1.8 2 0 0 2 2 2 0 Tubulin binding cofactor A zf-RING_2 PF13639.1 AEO54719.1 - 1.1 9.1 6.0 2.3 8.1 4.2 1.6 1 0 0 1 1 1 0 Ring finger domain SCO1-SenC PF02630.9 AEO54720.1 - 1.4e-59 200.6 0.0 1.8e-59 200.2 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC Thioredoxin_8 PF13905.1 AEO54720.1 - 0.0019 18.2 0.0 0.0037 17.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 AEO54720.1 - 0.0025 17.4 0.0 0.0052 16.4 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family Choline_kinase PF01633.15 AEO54721.1 - 1.6e-59 201.0 0.0 2.9e-59 200.1 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.9 AEO54721.1 - 1.6e-23 81.9 0.0 8e-23 79.6 0.0 2.1 2 0 0 2 2 2 1 Choline kinase N terminus APH PF01636.18 AEO54721.1 - 6.4e-07 29.3 0.9 6.4e-07 29.3 0.6 2.6 3 1 0 3 3 3 1 Phosphotransferase enzyme family DUF3433 PF11915.3 AEO54722.1 - 3.9e-19 68.6 27.8 7.6e-17 61.2 2.1 4.7 4 1 0 4 4 4 2 Protein of unknown function (DUF3433) DUF4604 PF15377.1 AEO54723.1 - 0.054 13.7 1.5 0.079 13.1 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) Hydrolase_6 PF13344.1 AEO54726.1 - 1.9e-26 91.8 0.0 5.6e-26 90.3 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 AEO54726.1 - 1.2e-12 47.3 0.7 1.3e-11 44.0 0.6 2.6 2 1 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 AEO54726.1 - 5.5e-05 23.6 0.0 0.35 11.2 0.0 3.3 2 2 1 3 3 3 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 AEO54726.1 - 7.6e-05 23.0 0.7 0.035 14.3 0.0 4.1 3 1 0 3 3 3 1 Haloacid dehalogenase-like hydrolase zf-CCHC PF00098.18 AEO54727.1 - 0.0093 15.8 1.1 0.013 15.3 0.7 1.2 1 0 0 1 1 1 1 Zinc knuckle FlgN PF05130.7 AEO54729.1 - 0.0051 17.0 1.4 0.0081 16.4 1.0 1.4 1 0 0 1 1 1 1 FlgN protein APG6 PF04111.7 AEO54729.1 - 0.0056 15.7 0.5 0.0069 15.4 0.3 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 OmpH PF03938.9 AEO54729.1 - 0.036 13.9 0.4 0.047 13.6 0.3 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1599 PF07659.6 AEO54729.1 - 0.086 12.9 2.6 5.7 7.0 0.1 2.3 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1599) DUF1664 PF07889.7 AEO54729.1 - 0.15 11.8 0.3 0.23 11.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Fzo_mitofusin PF04799.8 AEO54729.1 - 0.2 11.0 1.1 0.29 10.5 0.8 1.2 1 0 0 1 1 1 0 fzo-like conserved region DUF724 PF05266.9 AEO54729.1 - 0.22 11.1 3.0 0.61 9.6 2.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF724) CALCOCO1 PF07888.6 AEO54729.1 - 1.5 7.0 9.3 1.9 6.7 6.5 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2852 PF11014.3 AEO54729.1 - 2.5 8.0 6.2 2.6 8.0 3.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) OPT PF03169.10 AEO54730.1 - 3.4e-183 610.4 55.6 3.9e-183 610.2 38.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein E1-E2_ATPase PF00122.15 AEO54730.1 - 0.6 9.1 2.0 3.7 6.5 0.1 2.3 2 0 0 2 2 2 0 E1-E2 ATPase MoaE PF02391.12 AEO54731.1 - 6.7e-32 109.7 0.0 8.6e-32 109.3 0.0 1.1 1 0 0 1 1 1 1 MoaE protein G-patch PF01585.18 AEO54732.1 - 4.2e-12 45.6 2.2 9e-12 44.5 1.6 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 AEO54732.1 - 5e-05 23.0 1.3 5e-05 23.0 0.9 1.9 2 0 0 2 2 2 1 DExH-box splicing factor binding site RRM_1 PF00076.17 AEO54732.1 - 0.008 15.7 0.1 0.018 14.6 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RED_N PF07808.8 AEO54732.1 - 8.9 5.4 8.1 0.36 10.0 0.8 2.1 3 0 0 3 3 3 0 RED-like protein N-terminal region Asp PF00026.18 AEO54733.1 - 9.1e-61 205.8 0.0 1.3e-51 175.7 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.1 AEO54733.1 - 3.2e-11 43.4 0.0 2.4e-10 40.6 0.0 2.5 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 AEO54733.1 - 5.3e-05 23.6 0.5 3.3 8.2 0.1 3.5 3 0 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.1 AEO54733.1 - 6.3e-05 22.7 0.1 0.38 10.5 0.0 2.6 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.1 AEO54733.1 - 0.0036 16.8 0.0 2.9 7.4 0.0 2.3 2 0 0 2 2 2 2 Xylanase inhibitor C-terminal Nucleoplasmin PF03066.10 AEO54733.1 - 0.045 13.2 0.8 0.096 12.2 0.6 1.5 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 AEO54733.1 - 0.21 11.8 6.7 0.15 12.2 3.0 1.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PBP1_TM PF14812.1 AEO54733.1 - 0.24 11.7 4.2 0.42 10.9 2.9 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2457 PF10446.4 AEO54733.1 - 0.25 10.0 8.4 0.34 9.5 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) HATPase_c PF02518.21 AEO54734.1 - 4e-25 87.6 0.0 2.6e-24 85.0 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.1 AEO54734.1 - 5.4e-23 81.3 0.0 1.2e-07 32.0 0.0 3.6 3 0 0 3 3 3 3 PAS domain Response_reg PF00072.19 AEO54734.1 - 4.4e-16 58.8 0.5 8.2e-12 45.1 0.0 2.9 3 0 0 3 3 3 2 Response regulator receiver domain PAS_8 PF13188.1 AEO54734.1 - 1.9e-10 40.2 0.0 0.0006 19.5 0.0 3.9 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.6 AEO54734.1 - 2.4e-10 40.3 0.0 0.0002 21.3 0.0 3.2 2 0 0 2 2 2 2 PAS fold HisKA PF00512.20 AEO54734.1 - 3.6e-08 33.2 0.8 3.6e-07 30.0 0.0 3.0 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.5 AEO54734.1 - 6.7e-08 32.5 1.1 0.21 11.6 0.0 4.9 4 2 1 5 5 5 2 PAS fold PAS PF00989.19 AEO54734.1 - 1.4e-07 31.2 0.0 0.0031 17.2 0.0 3.2 3 1 0 3 3 3 2 PAS fold GAF_3 PF13492.1 AEO54734.1 - 0.0018 18.3 0.0 0.023 14.7 0.0 2.7 2 0 0 2 2 2 1 GAF domain HATPase_c_3 PF13589.1 AEO54734.1 - 0.041 13.5 0.0 1.5 8.4 0.0 2.8 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Dabb PF07876.7 AEO54735.1 - 4.1e-07 30.3 0.0 4.9e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Polyketide_cyc2 PF10604.4 AEO54736.1 - 3.8e-06 27.1 6.1 0.0066 16.6 0.3 2.9 1 1 2 3 3 3 2 Polyketide cyclase / dehydrase and lipid transport Methyltransf_2 PF00891.13 AEO54737.1 - 3.3e-33 114.8 0.0 5e-33 114.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 AEO54737.1 - 0.00016 22.2 0.0 0.00041 20.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO54738.1 - 2.5e-20 72.7 0.0 4.8e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO54738.1 - 3.3e-11 43.5 0.0 6.8e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO54738.1 - 2.2e-09 37.6 0.0 2.8e-08 34.1 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO54738.1 - 3.6e-09 37.1 0.0 3.8e-08 33.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO54738.1 - 3.8e-09 36.3 0.0 1.3e-07 31.3 0.0 2.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO54738.1 - 1.2e-06 28.7 0.0 3.5e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 AEO54738.1 - 0.00082 18.4 0.0 0.0019 17.2 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.14 AEO54738.1 - 0.0057 16.6 0.0 0.0088 16.0 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 AEO54738.1 - 0.012 15.6 0.0 0.13 12.3 0.0 2.6 2 1 0 2 2 2 0 Methyltransferase domain PrmA PF06325.8 AEO54738.1 - 0.039 13.0 0.0 0.076 12.1 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 AEO54738.1 - 0.057 12.5 0.0 3.3 6.7 0.0 2.7 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family PCI PF01399.22 AEO54739.1 - 1.3e-20 73.6 0.0 4.5e-20 71.9 0.0 1.9 1 0 0 1 1 1 1 PCI domain Asp_Glu_race_2 PF14669.1 AEO54739.1 - 0.00046 19.5 0.5 0.38 10.0 0.0 2.3 2 0 0 2 2 2 2 Putative aspartate racemase FbpA PF05833.6 AEO54740.1 - 1.2e-38 132.8 10.7 1.2e-38 132.8 7.4 2.1 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) DUF3441 PF11923.3 AEO54740.1 - 1.3e-35 121.3 0.1 3.8e-35 119.8 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3441) DUF814 PF05670.8 AEO54740.1 - 1.3e-24 85.8 0.0 3e-24 84.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF814) eIF-5a PF01287.15 AEO54741.1 - 2.3e-07 30.6 0.1 4.2e-07 29.8 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Peptidase_C1_2 PF03051.10 AEO54742.1 - 1.8e-25 89.3 0.1 1e-17 63.8 0.0 2.8 2 1 1 3 3 3 3 Peptidase C1-like family zf-CCCH PF00642.19 AEO54746.1 - 0.097 12.3 0.6 0.22 11.2 0.4 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) S1-P1_nuclease PF02265.11 AEO54747.1 - 1.1e-72 244.7 0.0 1.2e-72 244.5 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease PQ-loop PF04193.9 AEO54748.1 - 3e-39 132.3 7.0 1.4e-20 72.6 0.1 2.6 2 0 0 2 2 2 2 PQ loop repeat SelP_N PF04592.9 AEO54748.1 - 0.055 12.8 14.7 0.045 13.1 8.3 1.9 2 0 0 2 2 2 0 Selenoprotein P, N terminal region UPF0139 PF03669.8 AEO54750.1 - 1.6e-05 24.3 0.0 1.9e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) Med12 PF09497.5 AEO54751.1 - 5.3e-28 96.8 0.4 1.1e-27 95.7 0.3 1.6 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.3 AEO54751.1 - 0.0092 14.5 6.6 0.075 11.5 0.0 3.1 2 1 1 3 3 3 1 Eukaryotic Mediator 12 subunit domain TAN PF11640.3 AEO54751.1 - 0.028 14.1 0.1 0.065 12.9 0.1 1.5 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair FAD_binding_4 PF01565.18 AEO54752.1 - 2.6e-16 59.3 1.5 3.6e-16 58.8 1.0 1.2 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.9 AEO54752.1 - 2.2e-11 43.8 0.8 2.2e-06 27.4 0.0 2.3 2 0 0 2 2 2 2 D-arabinono-1,4-lactone oxidase RabGAP-TBC PF00566.13 AEO54753.1 - 2.3e-46 157.9 0.0 3.3e-46 157.4 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.1 AEO54753.1 - 1.4e-05 24.5 1.0 0.0036 17.0 0.2 3.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.1 AEO54753.1 - 0.00011 22.2 0.2 0.014 15.5 0.1 2.6 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 AEO54753.1 - 0.00044 19.3 0.1 0.036 13.3 0.2 3.4 3 0 0 3 3 3 1 EF hand DUF416 PF04222.7 AEO54753.1 - 0.088 11.9 0.1 1.6 7.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF416) DUF3245 PF11595.3 AEO54753.1 - 0.56 10.4 12.7 0.029 14.6 1.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) DUF4611 PF15387.1 AEO54753.1 - 6.1 7.0 14.9 11 6.2 2.2 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Pkinase PF00069.20 AEO54754.1 - 8.1e-64 215.2 0.0 9.4e-64 215.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO54754.1 - 8.5e-30 103.6 0.0 1.1e-29 103.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO54754.1 - 1.2e-05 24.4 0.0 1.6e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AEO54754.1 - 0.00055 19.7 0.8 0.063 13.0 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 AEO54754.1 - 0.028 13.2 0.0 0.042 12.6 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Exo_endo_phos PF03372.18 AEO54755.1 - 8.3e-14 52.1 0.7 1.3e-08 35.0 0.1 2.4 2 1 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family Mucin PF01456.12 AEO54755.1 - 0.039 13.7 22.6 0.58 9.9 8.0 2.5 2 0 0 2 2 2 0 Mucin-like glycoprotein Pkinase PF00069.20 AEO54756.1 - 1.5e-38 132.4 0.0 1.9e-38 132.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO54756.1 - 9.3e-14 51.1 0.0 1.3e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AEO54756.1 - 1.4e-05 24.9 0.1 0.0014 18.4 0.0 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 AEO54756.1 - 0.052 12.3 0.1 0.078 11.7 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pal1 PF08316.6 AEO54757.1 - 1e-46 158.8 0.5 1e-46 158.8 0.4 2.3 2 0 0 2 2 2 1 Pal1 cell morphology protein PRCC PF10253.4 AEO54757.1 - 3.8 8.1 10.6 0.39 11.3 4.0 1.9 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting TMEM171 PF15471.1 AEO54758.1 - 0.16 10.7 1.0 0.26 10.0 0.7 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 Fasciclin PF02469.17 AEO54759.1 - 6.9e-41 139.2 0.0 1.7e-26 92.7 0.0 2.6 2 1 0 2 2 2 2 Fasciclin domain zf-C2H2_4 PF13894.1 AEO54760.1 - 6.9e-05 22.9 23.7 0.015 15.5 2.1 3.9 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 AEO54760.1 - 0.0038 17.4 22.3 0.031 14.6 0.5 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type Adeno_E3_CR2 PF02439.10 AEO54760.1 - 0.038 13.5 0.2 0.08 12.4 0.2 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 HSP70 PF00012.15 AEO54762.1 - 4.3e-79 266.0 2.1 4.3e-79 266.0 1.5 1.7 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 AEO54762.1 - 5.5e-07 28.4 0.6 1.2e-06 27.3 0.4 1.5 1 1 0 1 1 1 1 MreB/Mbl protein Pap_E4 PF02711.9 AEO54762.1 - 0.039 14.7 0.6 0.25 12.1 0.1 2.3 2 0 0 2 2 2 0 E4 protein Nop14 PF04147.7 AEO54762.1 - 0.27 9.0 7.2 0.49 8.2 5.0 1.3 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.8 AEO54762.1 - 3.4 7.2 9.3 2.1 7.9 4.7 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region DNA_pol_phi PF04931.8 AEO54762.1 - 5.1 4.7 9.4 7.6 4.1 6.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi NT-C2 PF10358.4 AEO54763.1 - 6.9e-26 90.4 0.0 1.5e-25 89.3 0.0 1.5 1 1 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins POP1 PF06978.6 AEO54764.1 - 1.4e-67 226.9 14.4 1.4e-67 226.9 10.0 1.7 2 0 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 AEO54764.1 - 4.4e-32 109.7 1.3 6.9e-32 109.1 0.2 1.9 2 0 0 2 2 2 1 POPLD (NUC188) domain IBR PF01485.16 AEO54765.1 - 6.9e-10 38.6 21.7 3.3e-06 26.8 5.1 3.9 3 1 0 3 3 3 2 IBR domain DUF605 PF04652.11 AEO54765.1 - 0.47 9.7 33.0 0.0082 15.5 14.3 2.3 2 0 0 2 2 2 0 Vta1 like SH3_1 PF00018.23 AEO54766.1 - 5.6e-14 51.2 0.0 8.3e-14 50.7 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 AEO54766.1 - 4.1e-11 42.2 0.1 6e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 AEO54766.1 - 1.9e-06 27.2 0.0 3.1e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain DUF4004 PF13171.1 AEO54766.1 - 0.14 12.3 0.0 0.35 10.9 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4004) DUF910 PF06014.6 AEO54766.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF910) Pex14_N PF04695.8 AEO54766.1 - 0.62 10.1 12.5 1.6 8.8 5.0 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PRCC PF10253.4 AEO54766.1 - 1.4 9.5 11.2 4.7 7.8 4.7 2.1 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting CNH PF00780.17 AEO54767.1 - 2.7e-82 276.2 0.0 7.9e-82 274.7 0.0 1.7 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.1 AEO54767.1 - 4.8e-43 146.3 0.0 9.7e-43 145.3 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 AEO54767.1 - 6.6e-35 120.6 0.0 1.2e-34 119.7 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 AEO54767.1 - 8e-15 54.3 0.1 1.5e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH PF00169.24 AEO54767.1 - 0.012 15.8 0.0 0.21 11.7 0.0 2.8 2 2 0 2 2 2 0 PH domain ATP-synt_C PF00137.16 AEO54768.1 - 5.3e-27 93.5 26.0 3.5e-16 58.8 4.3 2.1 2 0 0 2 2 2 2 ATP synthase subunit C FPN1 PF06963.7 AEO54768.1 - 2.8 6.2 7.2 6.6 4.9 0.0 2.6 2 1 0 2 2 2 0 Ferroportin1 (FPN1) Metallophos PF00149.23 AEO54770.1 - 4.6e-07 29.4 1.8 9.4e-07 28.4 1.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase B12-binding PF02310.14 AEO54770.1 - 0.0068 16.2 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 B12 binding domain Ribosomal_L22 PF00237.14 AEO54770.1 - 0.0074 16.2 0.0 0.022 14.7 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e Isy1 PF06246.7 AEO54771.1 - 4.2e-85 285.2 0.3 6.4e-85 284.6 0.2 1.3 1 1 0 1 1 1 1 Isy1-like splicing family YolD PF08863.5 AEO54771.1 - 0.02 14.7 0.1 0.082 12.7 0.0 1.9 2 0 0 2 2 2 0 YolD-like protein DDOST_48kD PF03345.9 AEO54773.1 - 1.7e-163 544.1 0.0 2e-163 543.8 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta PsbX PF06596.6 AEO54774.1 - 0.15 11.7 1.0 0.22 11.2 0.7 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) Beach PF02138.13 AEO54775.1 - 4.6e-109 364.0 0.0 8.5e-109 363.1 0.0 1.5 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 AEO54775.1 - 8.2e-12 44.9 0.1 4.4e-11 42.5 0.0 2.2 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.1 AEO54775.1 - 6.8e-11 42.6 0.0 1.6e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.27 AEO54775.1 - 2.8e-07 30.1 1.2 0.12 12.3 0.0 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat Peptidase_S8 PF00082.17 AEO54776.1 - 2.4e-52 177.8 10.1 3.8e-52 177.1 7.0 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 AEO54776.1 - 5.2e-23 81.4 0.5 1.3e-22 80.1 0.4 1.7 1 0 0 1 1 1 1 Peptidase inhibitor I9 Exonuc_X-T_C PF08411.5 AEO54777.1 - 0.26 10.2 1.1 0.37 9.7 0.1 1.7 2 0 0 2 2 2 0 Exonuclease C-terminal FAD_binding_4 PF01565.18 AEO54778.1 - 3.2e-21 75.2 2.8 3.7e-21 75.0 0.5 2.1 2 0 0 2 2 2 1 FAD binding domain Hist_deacetyl PF00850.14 AEO54778.1 - 0.1 11.8 0.1 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Histone deacetylase domain ATP12 PF07542.6 AEO54780.1 - 5.8e-26 90.8 0.2 1.3e-25 89.6 0.0 1.6 2 0 0 2 2 2 1 ATP12 chaperone protein 2OG-FeII_Oxy_2 PF13532.1 AEO54781.1 - 1e-20 74.4 0.0 1.7e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 AEO54781.1 - 0.0072 16.5 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AMP-binding PF00501.23 AEO54782.1 - 1.2e-82 277.5 0.0 1.5e-82 277.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 AEO54782.1 - 1.6e-17 64.2 2.0 3e-17 63.3 0.3 2.4 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain Pyridoxal_deC PF00282.14 AEO54783.1 - 3.9e-57 193.3 0.0 5.4e-57 192.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 AEO54783.1 - 0.0015 17.3 0.0 0.0034 16.1 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Pirin PF02678.11 AEO54784.1 - 3.5e-25 87.9 1.1 9.1e-15 54.4 0.2 2.3 2 0 0 2 2 2 2 Pirin Cupin_2 PF07883.6 AEO54784.1 - 0.0002 20.7 2.6 0.017 14.6 0.0 3.5 4 0 0 4 4 4 2 Cupin domain Ank_5 PF13857.1 AEO54786.1 - 6.4e-06 26.2 0.1 1.5e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 AEO54786.1 - 0.005 16.5 0.8 0.011 15.5 0.2 1.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 AEO54786.1 - 0.026 14.8 0.0 0.061 13.6 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_3 PF13606.1 AEO54786.1 - 0.05 13.8 0.0 0.31 11.4 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeat zf-C2H2_3 PF13878.1 AEO54786.1 - 0.31 10.6 1.7 0.36 10.4 0.0 1.9 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO PLRV_ORF5 PF01690.12 AEO54786.1 - 1.5 7.8 10.4 0.17 10.9 0.6 2.4 3 0 0 3 3 3 0 Potato leaf roll virus readthrough protein CFEM PF05730.6 AEO54787.1 - 0.00023 20.8 2.4 0.00023 20.8 1.6 3.0 2 0 0 2 2 2 1 CFEM domain T5orf172 PF10544.4 AEO54788.1 - 1.1e-16 61.0 0.0 1.9e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.1 AEO54788.1 - 2.3e-15 56.7 0.2 3.6e-15 56.1 0.1 1.3 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 Zn_clus PF00172.13 AEO54789.1 - 1.2e-08 34.6 11.9 2.3e-08 33.7 8.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SOG2 PF10428.4 AEO54789.1 - 0.018 13.7 8.1 0.028 13.0 5.6 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DUF605 PF04652.11 AEO54789.1 - 1 8.7 23.2 0.035 13.5 8.0 2.0 2 0 0 2 2 2 0 Vta1 like Annexin PF00191.15 AEO54790.1 - 1.5e-20 72.8 2.1 4.7e-05 23.2 0.0 4.7 4 1 0 4 4 4 4 Annexin GPI2 PF06432.6 AEO54792.1 - 1.2e-127 425.1 1.7 6.9e-82 274.9 0.2 2.0 2 0 0 2 2 2 2 Phosphatidylinositol N-acetylglucosaminyltransferase DUF1049 PF06305.6 AEO54792.1 - 0.2 11.1 2.0 2.6 7.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) CNH PF00780.17 AEO54793.1 - 1.2e-68 231.5 0.0 1.9e-68 230.8 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 AEO54793.1 - 1.2e-31 109.9 0.0 1.8e-31 109.3 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 AEO54793.1 - 8e-11 42.0 0.0 9.8e-10 38.5 0.0 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 AEO54793.1 - 5.3e-05 23.3 0.0 0.00015 21.9 0.0 1.8 1 1 0 1 1 1 1 PH domain Tropomyosin PF00261.15 AEO54793.1 - 0.22 10.5 3.3 0.36 9.8 2.3 1.2 1 0 0 1 1 1 0 Tropomyosin Sod_Cu PF00080.15 AEO54794.1 - 3.2e-47 160.2 4.8 3.7e-47 160.0 3.3 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) SNase PF00565.12 AEO54795.1 - 7.8e-71 235.2 0.3 3e-22 78.9 0.0 5.3 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 AEO54795.1 - 6.5e-26 90.5 0.0 2.3e-25 88.8 0.0 1.9 2 0 0 2 2 2 1 Tudor domain SMN PF06003.7 AEO54795.1 - 1.2e-06 27.8 0.0 2.3e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) Transaldolase PF00923.14 AEO54796.1 - 4.2e-93 311.6 0.9 4.8e-93 311.4 0.6 1.0 1 0 0 1 1 1 1 Transaldolase Metallophos_2 PF12850.2 AEO54797.1 - 2.9e-09 36.9 0.0 5.7e-09 36.0 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 AEO54797.1 - 2.1e-05 24.0 0.4 6.3e-05 22.4 0.2 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase FAM176 PF14851.1 AEO54797.1 - 4.2 7.0 7.1 4.6 6.9 0.3 2.9 3 0 0 3 3 3 0 FAM176 family Pet191_N PF10203.4 AEO54798.1 - 8e-28 96.2 3.9 1.1e-27 95.8 2.7 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 AEO54798.1 - 0.72 9.6 4.4 6 6.7 0.3 2.5 1 1 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Abhydro_lipase PF04083.11 AEO54799.1 - 1e-21 75.9 0.1 1.8e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 AEO54799.1 - 2.1e-19 69.9 0.2 3.4e-19 69.3 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AEO54799.1 - 0.0001 22.1 0.0 0.00095 18.9 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 AEO54799.1 - 0.00058 19.3 0.0 0.32 10.3 0.0 2.3 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Nucleoplasmin PF03066.10 AEO54799.1 - 0.048 13.1 2.9 0.077 12.5 2.0 1.2 1 0 0 1 1 1 0 Nucleoplasmin Myc_N PF01056.13 AEO54799.1 - 0.37 9.8 2.6 0.65 9.1 1.8 1.3 1 0 0 1 1 1 0 Myc amino-terminal region CENP-B_dimeris PF09026.5 AEO54799.1 - 0.53 10.5 6.3 1.3 9.3 4.4 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Daxx PF03344.10 AEO54799.1 - 0.63 8.4 2.9 0.88 7.9 2.0 1.1 1 0 0 1 1 1 0 Daxx Family MMR_HSR1 PF01926.18 AEO54801.1 - 2.8e-10 40.1 0.0 5e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 AEO54801.1 - 0.003 17.4 0.0 0.053 13.3 0.0 2.3 2 0 0 2 2 2 1 Dynamin family DUF258 PF03193.11 AEO54801.1 - 0.025 13.7 0.1 0.2 10.8 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function, DUF258 FeoB_N PF02421.13 AEO54801.1 - 0.028 13.7 0.1 0.077 12.2 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_17 PF13207.1 AEO54801.1 - 0.039 14.7 0.1 0.22 12.3 0.0 2.3 3 0 0 3 3 3 0 AAA domain Arf PF00025.16 AEO54801.1 - 0.095 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_29 PF13555.1 AEO54801.1 - 0.1 12.1 0.0 0.28 10.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 AEO54801.1 - 0.12 12.7 0.0 0.36 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 AEO54801.1 - 0.13 12.2 0.7 0.55 10.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain PHD PF00628.24 AEO54802.1 - 1.2e-09 37.6 2.1 1.2e-09 37.6 1.5 1.7 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 AEO54802.1 - 0.035 13.4 3.1 0.058 12.7 2.1 1.4 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.17 AEO54802.1 - 2.2 8.1 5.3 3.2 7.5 0.3 2.3 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Dicty_REP PF05086.7 AEO54804.1 - 4.1 5.0 3.7 7.9 4.0 2.6 1.4 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RuBisCO_large_N PF02788.11 AEO54806.1 - 0.056 13.1 0.3 0.086 12.5 0.2 1.3 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, N-terminal domain adh_short_C2 PF13561.1 AEO54807.1 - 5.9e-23 81.8 0.0 1.2e-15 57.9 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 AEO54807.1 - 3e-14 53.2 1.6 3.4e-13 49.8 0.1 2.1 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 AEO54807.1 - 2.3e-08 33.9 0.1 4e-08 33.1 0.1 1.3 1 0 0 1 1 1 1 KR domain Carboxyl_trans PF01039.17 AEO54808.1 - 7.7e-142 473.1 0.0 1e-141 472.7 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 AEO54808.1 - 0.0023 17.1 0.1 0.17 11.0 0.0 2.5 3 0 0 3 3 3 2 Malonate decarboxylase gamma subunit (MdcE) Acyl-CoA_dh_1 PF00441.19 AEO54809.1 - 1.9e-41 141.6 1.9 1.9e-41 141.6 1.3 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 AEO54809.1 - 5.2e-31 107.5 0.1 1.2e-30 106.4 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 AEO54809.1 - 4.7e-20 70.8 0.1 9.7e-20 69.8 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 AEO54809.1 - 2.4e-14 53.7 0.7 2.4e-14 53.7 0.5 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 AEO54809.1 - 0.00093 18.6 0.3 0.0038 16.6 0.2 1.9 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal NUDIX PF00293.23 AEO54810.1 - 1.9e-12 46.9 0.1 3.3e-11 42.9 0.1 2.0 1 1 0 1 1 1 1 NUDIX domain DLH PF01738.13 AEO54811.1 - 2.3e-06 27.0 0.0 3.6e-06 26.4 0.0 1.3 1 1 0 1 1 1 1 Dienelactone hydrolase family WD40 PF00400.27 AEO54812.1 - 7.9e-12 44.5 14.7 8.9e-07 28.5 0.5 4.7 4 0 0 4 4 4 2 WD domain, G-beta repeat RWD PF05773.17 AEO54812.1 - 0.0094 15.8 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 1 RWD domain UQ_con PF00179.21 AEO54813.1 - 4.4e-47 159.0 0.0 5.1e-47 158.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AEO54813.1 - 7.4e-05 22.5 0.0 9.6e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 AEO54813.1 - 0.0081 15.8 0.1 0.014 15.0 0.0 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.17 AEO54813.1 - 0.041 13.7 0.0 0.051 13.4 0.0 1.3 1 0 0 1 1 1 0 RWD domain ADH_zinc_N PF00107.21 AEO54815.1 - 3.7e-12 45.9 0.0 6.8e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AEO54815.1 - 0.0017 18.1 0.0 0.0036 17.0 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.20 AEO54815.1 - 0.0037 17.2 0.5 0.0075 16.2 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.1 AEO54815.1 - 0.012 16.5 0.0 0.028 15.3 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Ribosomal_L12 PF00542.14 AEO54815.1 - 0.07 13.1 0.2 0.24 11.4 0.1 1.9 1 0 0 1 1 1 0 Ribosomal protein L7/L12 C-terminal domain KR PF08659.5 AEO54815.1 - 0.094 12.3 0.4 0.18 11.4 0.0 1.8 2 0 0 2 2 2 0 KR domain PI3Ka PF00613.15 AEO54816.1 - 7.7e-59 197.9 0.3 1.4e-58 197.1 0.2 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 AEO54816.1 - 8.4e-44 149.7 0.1 1.7e-42 145.4 0.1 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 AEO54816.1 - 1.1e-33 116.0 0.0 1.7e-33 115.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DOCK-C2 PF14429.1 AEO54816.1 - 0.014 15.0 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 C2 domain in Dock180 and Zizimin proteins Nse4_C PF08743.5 AEO54817.1 - 1e-35 121.6 0.0 2e-35 120.6 0.0 1.5 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 AEO54817.1 - 7.6e-19 67.3 0.0 1.8e-18 66.0 0.0 1.7 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE Plasmid_stabil PF05016.9 AEO54817.1 - 0.12 12.8 0.4 0.94 9.9 0.0 2.3 2 0 0 2 2 2 0 Plasmid stabilisation system protein DUF948 PF06103.6 AEO54818.1 - 2.9 7.8 5.5 3.6 7.5 0.0 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF4336 PF14234.1 AEO54819.1 - 8.2e-15 54.7 0.0 1.9e-09 37.1 0.0 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4336) Amidase PF01425.16 AEO54820.1 - 7.2e-88 295.3 6.7 3.1e-33 115.3 0.0 3.1 3 0 0 3 3 3 3 Amidase Mito_fiss_reg PF05308.6 AEO54820.1 - 0.0012 18.2 7.6 0.0021 17.4 5.2 1.3 1 0 0 1 1 1 1 Mitochondrial fission regulator PRP38 PF03371.10 AEO54821.1 - 1.3e-62 210.4 0.0 1.6e-62 210.2 0.0 1.1 1 0 0 1 1 1 1 PRP38 family PRP38_assoc PF12871.2 AEO54821.1 - 0.0042 17.5 24.9 0.0077 16.7 17.2 1.5 1 0 0 1 1 1 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Paf1 PF03985.8 AEO54821.1 - 0.048 12.4 6.9 0.058 12.1 4.7 1.1 1 0 0 1 1 1 0 Paf1 DUF1509 PF07420.6 AEO54821.1 - 0.054 12.7 10.1 0.076 12.2 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) PI3K_1B_p101 PF10486.4 AEO54821.1 - 0.093 10.2 1.6 0.12 9.9 1.1 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CDC45 PF02724.9 AEO54821.1 - 1.8 6.5 12.0 2.3 6.1 8.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Corona_nucleoca PF00937.13 AEO54821.1 - 7.2 5.4 11.3 11 4.9 7.8 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein MmgE_PrpD PF03972.9 AEO54824.1 - 1.5e-150 501.2 0.0 1.8e-150 501.0 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family WD40 PF00400.27 AEO54825.1 - 6.3e-25 86.1 13.2 1.4e-09 37.4 0.5 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat PQQ_3 PF13570.1 AEO54825.1 - 0.0061 16.7 0.3 1.5 9.2 0.1 2.8 2 0 0 2 2 2 1 PQQ-like domain PD40 PF07676.7 AEO54825.1 - 0.1 12.3 2.5 0.23 11.1 0.0 2.8 3 1 1 4 4 4 0 WD40-like Beta Propeller Repeat RRN3 PF05327.6 AEO54825.1 - 0.56 8.2 10.5 0.78 7.7 7.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Fork_head_N PF08430.7 AEO54826.1 - 2.9 8.3 16.5 3 8.2 11.4 1.1 1 0 0 1 1 1 0 Forkhead N-terminal region SET PF00856.23 AEO54827.1 - 9.9e-13 48.7 0.0 1.1e-11 45.2 0.0 2.1 1 1 0 1 1 1 1 SET domain SOG2 PF10428.4 AEO54827.1 - 0.021 13.5 4.0 0.026 13.1 2.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Mucin PF01456.12 AEO54827.1 - 3.2 7.5 26.0 6.8 6.4 18.0 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Sporozoite_P67 PF05642.6 AEO54827.1 - 3.2 5.4 9.8 4.7 4.9 6.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Herpes_capsid PF06112.6 AEO54827.1 - 5.8 6.9 9.2 9.9 6.1 6.3 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Coq4 PF05019.8 AEO54828.1 - 1.8e-99 331.1 0.0 2.1e-99 330.9 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 YqzE PF14038.1 AEO54828.1 - 1.9 8.3 4.0 2.1 8.1 1.5 1.9 2 0 0 2 2 2 0 YqzE-like protein dsDNA_bind PF01984.15 AEO54829.1 - 7.3e-34 115.9 13.9 8.9e-34 115.7 9.6 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF4615 PF15393.1 AEO54829.1 - 0.039 14.1 1.3 0.039 14.1 0.9 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4615) ApbA_C PF08546.6 AEO54830.1 - 1.6e-18 66.8 0.0 2.4e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 AEO54830.1 - 1.6e-15 56.8 0.0 2.4e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA GIDE PF12483.3 AEO54830.1 - 0.053 12.8 0.1 0.17 11.2 0.0 1.8 2 0 0 2 2 2 0 E3 Ubiquitin ligase Sas10_Utp3 PF04000.10 AEO54831.1 - 1.1e-17 63.9 0.3 1.6e-17 63.4 0.2 1.2 1 0 0 1 1 1 1 Sas10/Utp3/C1D family DUF2076 PF09849.4 AEO54832.1 - 1.2e-08 35.2 9.6 1.6e-08 34.9 6.7 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 AEO54832.1 - 0.012 15.4 0.7 0.018 14.9 0.5 1.3 1 0 0 1 1 1 0 CHCH domain GCK PF07802.6 AEO54832.1 - 0.012 15.6 0.0 0.018 15.1 0.0 1.2 1 0 0 1 1 1 0 GCK domain Nucleoporin_FG PF13634.1 AEO54832.1 - 0.23 11.7 23.5 0.37 11.0 16.3 1.3 1 0 0 1 1 1 0 Nucleoporin FG repeat region DUF759 PF05537.6 AEO54832.1 - 0.29 9.8 1.0 0.35 9.5 0.7 1.1 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF759) UBX PF00789.15 AEO54833.1 - 9e-17 60.9 0.0 2.1e-16 59.7 0.0 1.7 1 0 0 1 1 1 1 UBX domain DUF2763 PF10961.3 AEO54833.1 - 0.067 13.5 0.5 0.16 12.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2763) SpoIIIAH PF12685.2 AEO54833.1 - 0.068 12.6 11.2 1.5 8.2 8.7 2.1 2 0 0 2 2 2 0 SpoIIIAH-like protein SURF1 PF02104.10 AEO54834.1 - 1.6e-65 220.9 0.1 2.1e-65 220.5 0.0 1.1 1 0 0 1 1 1 1 SURF1 family Synthase_beta PF11421.3 AEO54834.1 - 0.91 10.2 5.0 0.25 12.0 0.4 2.2 1 1 1 2 2 2 0 ATP synthase F1 beta subunit CENP-T PF15511.1 AEO54835.1 - 2e-119 399.5 12.5 2e-119 399.5 8.6 1.9 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T CENP-S PF15630.1 AEO54835.1 - 2.4e-09 37.2 0.1 4.1e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S Histone PF00125.19 AEO54835.1 - 2e-06 27.8 0.0 3.6e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 AEO54835.1 - 7.7e-06 25.8 0.0 1.4e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIIA PF03153.8 AEO54835.1 - 0.014 15.3 0.2 0.014 15.3 0.2 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Bromo_TP PF07524.8 AEO54835.1 - 0.18 11.5 0.0 0.6 9.8 0.0 1.8 2 0 0 2 2 2 0 Bromodomain associated Ras PF00071.17 AEO54836.1 - 3.4e-52 176.0 0.0 3.9e-52 175.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AEO54836.1 - 2.1e-16 60.5 0.0 3.2e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AEO54836.1 - 3.5e-08 32.8 0.0 4.4e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 AEO54836.1 - 0.0006 19.2 0.0 0.0025 17.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF2370 PF10176.4 AEO54837.1 - 0.012 14.9 4.4 0.014 14.7 2.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2370) TMEM51 PF15345.1 AEO54837.1 - 0.043 13.4 0.1 0.067 12.8 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 hEGF PF12661.2 AEO54838.1 - 0.014 15.4 3.2 0.033 14.2 2.2 1.7 1 0 0 1 1 1 0 Human growth factor-like EGF EGF_2 PF07974.8 AEO54838.1 - 0.58 10.3 11.1 1 9.5 7.7 1.4 1 0 0 1 1 1 0 EGF-like domain Ras PF00071.17 AEO54839.1 - 2.7e-51 173.1 0.0 3.1e-51 172.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AEO54839.1 - 2.7e-17 63.3 0.0 5.3e-17 62.4 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 AEO54839.1 - 5.8e-09 35.4 0.0 6.8e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 AEO54839.1 - 1.9e-06 27.4 0.1 6.6e-05 22.4 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 AEO54839.1 - 0.00042 20.2 0.0 0.00065 19.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 AEO54839.1 - 0.021 14.8 2.5 0.29 11.0 0.2 2.4 1 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 AEO54839.1 - 0.034 14.2 0.5 0.63 10.1 0.2 2.6 1 1 1 2 2 2 0 AAA domain PQ-loop PF04193.9 AEO54840.1 - 0.031 13.8 1.4 0.064 12.8 0.2 1.9 1 1 1 2 2 2 0 PQ loop repeat MFS_1 PF07690.11 AEO54840.1 - 0.031 13.0 6.8 0.039 12.6 4.7 1.2 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF2970 PF11174.3 AEO54840.1 - 0.12 11.9 2.5 0.56 9.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) CMS1 PF14617.1 AEO54841.1 - 5.6e-98 327.0 4.8 6.3e-98 326.8 3.3 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 AEO54841.1 - 6.2e-08 32.3 0.0 6.8e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase PI-PLC-X PF00388.14 AEO54842.1 - 2e-58 195.9 0.0 1e-57 193.6 0.0 2.0 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 AEO54842.1 - 7.5e-35 119.4 0.0 1.4e-34 118.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain Cupin_2 PF07883.6 AEO54844.1 - 0.00061 19.2 0.5 0.00082 18.8 0.3 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 AEO54844.1 - 0.13 11.9 0.2 0.15 11.7 0.2 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain 4HBT_3 PF13622.1 AEO54845.1 - 0.0096 15.6 1.9 0.013 15.2 1.3 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily CAP_N PF01213.14 AEO54845.1 - 7.6 5.7 15.2 9.8 5.3 10.5 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal 2OG-FeII_Oxy_3 PF13640.1 AEO54846.1 - 1.6e-11 44.5 0.0 2.9e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 AEO54846.1 - 1.6e-06 27.6 0.0 2.8e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 AEO54846.1 - 0.00038 20.6 0.0 0.00067 19.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RdRP PF05183.7 AEO54847.1 - 1.1e-152 509.8 0.0 1.3e-152 509.5 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase FAD-oxidase_C PF02913.14 AEO54848.1 - 7.3e-61 205.6 0.1 1e-60 205.1 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 AEO54848.1 - 4.4e-34 116.9 0.0 9.1e-34 115.9 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain Ribosomal_S4e PF00900.15 AEO54849.1 - 2.3e-32 110.4 0.5 4.5e-32 109.5 0.3 1.5 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 AEO54849.1 - 5.9e-19 67.6 4.9 1.2e-18 66.6 3.4 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 AEO54849.1 - 2.1e-06 27.0 0.0 3.9e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 AEO54849.1 - 0.00033 20.2 0.9 0.00033 20.2 0.6 3.1 4 0 0 4 4 4 1 KOW motif Myb_DNA-binding PF00249.26 AEO54850.1 - 1.1e-14 54.2 0.4 4.5e-08 33.0 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 AEO54850.1 - 1.7e-11 44.0 0.2 0.00017 21.6 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Glyco_hydro_18 PF00704.23 AEO54851.1 - 2.5e-18 66.6 0.6 8.8e-18 64.8 0.4 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 AEO54851.1 - 1.1e-11 44.3 0.0 2.3e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 LysM domain Mid2 PF04478.7 AEO54852.1 - 2.8e-06 26.8 1.0 2.8e-06 26.8 0.7 2.3 1 1 2 3 3 3 1 Mid2 like cell wall stress sensor Herpes_gE PF02480.11 AEO54852.1 - 0.014 13.6 0.0 0.014 13.6 0.0 2.2 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E DUF533 PF04391.7 AEO54852.1 - 0.14 11.4 0.1 0.14 11.4 0.0 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF533) DUF605 PF04652.11 AEO54852.1 - 0.19 11.1 24.5 0.32 10.3 17.0 1.4 1 0 0 1 1 1 0 Vta1 like DUF572 PF04502.8 AEO54852.1 - 1.5 7.9 10.9 1.9 7.5 7.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) RR_TM4-6 PF06459.7 AEO54852.1 - 2.5 7.9 7.6 5.5 6.8 5.3 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SOG2 PF10428.4 AEO54852.1 - 2.7 6.5 17.1 3.2 6.2 11.8 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Mitofilin PF09731.4 AEO54852.1 - 2.9 6.4 7.2 3.8 6.0 5.0 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein IER PF05760.7 AEO54852.1 - 5.1 6.9 12.8 6.7 6.5 8.9 1.2 1 0 0 1 1 1 0 Immediate early response protein (IER) PAM2 PF07145.10 AEO54854.1 - 2.4e-06 26.6 14.1 0.12 11.9 1.3 5.6 5 0 0 5 5 5 3 Ataxin-2 C-terminal region zf-C2H2 PF00096.21 AEO54855.1 - 2.2e-10 40.2 10.4 4.8e-05 23.4 2.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AEO54855.1 - 4.4e-07 29.7 6.9 0.011 15.9 2.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AEO54855.1 - 1.7e-06 27.9 8.3 0.00046 20.3 0.2 2.7 2 0 0 2 2 2 2 Zinc-finger double domain BolA PF01722.13 AEO54855.1 - 0.007 16.2 0.2 4.9 7.1 0.0 2.3 2 0 0 2 2 2 2 BolA-like protein zf-H2C2_5 PF13909.1 AEO54855.1 - 0.076 13.2 5.2 0.085 13.1 2.1 2.2 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-CHY PF05495.7 AEO54855.1 - 0.14 12.3 1.6 0.23 11.6 1.1 1.3 1 0 0 1 1 1 0 CHY zinc finger zf-met PF12874.2 AEO54855.1 - 0.31 11.3 2.8 7.1 6.9 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-LYAR PF08790.6 AEO54855.1 - 1.5 8.6 3.1 5.5 6.7 0.1 2.4 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2_6 PF13912.1 AEO54855.1 - 3.2 7.7 9.8 4.4 7.3 0.3 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger Ctr PF04145.10 AEO54856.1 - 1.1e-14 54.6 0.0 1.4e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family SRF-TF PF00319.13 AEO54857.1 - 8.5e-24 82.5 0.4 1.1e-23 82.1 0.2 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Tetraspannin PF00335.15 AEO54858.1 - 3e-08 33.1 5.7 4.1e-08 32.7 3.9 1.2 1 0 0 1 1 1 1 Tetraspanin family DUF1282 PF06930.7 AEO54858.1 - 0.15 11.6 4.5 0.27 10.8 3.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) DUF1772 PF08592.6 AEO54858.1 - 0.39 10.4 4.1 0.17 11.5 0.4 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) DUF805 PF05656.9 AEO54858.1 - 9.1 6.1 7.6 24 4.7 5.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF805) Mg_trans_NIPA PF05653.9 AEO54859.1 - 3.9e-16 58.8 4.3 6.2e-16 58.2 3.0 1.3 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 AEO54859.1 - 1.9e-06 27.9 11.1 0.00015 21.7 0.4 2.5 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 AEO54859.1 - 0.0031 16.4 0.2 0.0045 15.9 0.1 1.3 1 0 0 1 1 1 1 UAA transporter family Multi_Drug_Res PF00893.14 AEO54859.1 - 0.34 11.3 5.0 7.6 7.0 0.2 2.8 2 0 0 2 2 2 0 Small Multidrug Resistance protein vATP-synt_E PF01991.13 AEO54860.1 - 6.3e-45 152.8 12.4 8e-45 152.5 8.6 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit YonK PF09642.5 AEO54860.1 - 0.041 13.5 0.1 0.12 12.0 0.0 1.8 1 0 0 1 1 1 0 YonK protein MRP-63 PF14978.1 AEO54860.1 - 0.15 12.4 1.5 0.33 11.4 1.1 1.5 1 0 0 1 1 1 0 Mitochondrial ribosome protein 63 DUF2255 PF10012.4 AEO54860.1 - 1 9.3 5.2 0.39 10.6 0.7 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2255) Chlamy_scaf PF09675.5 AEO54861.1 - 0.12 12.4 0.0 2.3 8.2 0.0 2.9 3 0 0 3 3 3 0 Chlamydia-phage Chp2 scaffold (Chlamy_scaf) E1-E2_ATPase PF00122.15 AEO54862.1 - 4.8e-14 51.9 0.1 2.1e-13 49.8 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 AEO54862.1 - 3.4e-13 49.3 0.0 9.6e-13 47.9 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 AEO54862.1 - 2.3e-11 44.2 0.0 7e-11 42.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 AEO54862.1 - 8.5e-11 42.6 1.9 2.1e-05 25.0 0.3 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 AEO54862.1 - 0.014 14.9 0.5 0.029 13.9 0.3 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Aldedh PF00171.17 AEO54863.1 - 5.7e-114 381.0 0.0 6.7e-114 380.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GATA PF00320.22 AEO54864.1 - 3.5e-16 58.2 1.9 3.5e-16 58.2 1.3 2.3 2 0 0 2 2 2 1 GATA zinc finger DUF1752 PF08550.5 AEO54864.1 - 3.2e-12 45.8 1.2 5.4e-12 45.0 0.9 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Dicty_REP PF05086.7 AEO54864.1 - 0.011 13.5 6.7 0.027 12.2 4.6 1.5 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CFEM PF05730.6 AEO54866.1 - 0.015 15.0 4.0 0.028 14.2 2.8 1.4 1 0 0 1 1 1 0 CFEM domain Pkinase PF00069.20 AEO54867.1 - 3.3e-58 196.8 0.0 1.8e-57 194.4 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO54867.1 - 1.6e-28 99.5 0.1 3.1e-20 72.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 AEO54867.1 - 8.1e-07 29.4 0.2 2.2e-06 28.0 0.2 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 AEO54867.1 - 0.00031 19.7 0.3 0.002 17.1 0.0 2.2 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 AEO54867.1 - 0.0044 16.7 0.1 0.082 12.6 0.0 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 AEO54867.1 - 0.068 12.2 0.0 0.18 10.8 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family MFS_1 PF07690.11 AEO54869.1 - 3e-31 108.4 35.7 3e-31 108.4 24.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily ApbA PF02558.11 AEO54870.1 - 1.4e-22 79.7 0.0 2.1e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 AEO54870.1 - 1.2e-19 70.4 0.0 1.8e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Herpes_LMP1 PF05297.6 AEO54870.1 - 5.2 5.9 8.3 12 4.7 5.7 1.5 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF3176 PF11374.3 AEO54872.1 - 1.8e-31 108.2 0.7 1.8e-31 108.2 0.5 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) Rpr2 PF04032.11 AEO54873.1 - 7.9e-22 76.9 0.2 2.2e-21 75.5 0.1 1.7 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DEAD PF00270.24 AEO54874.1 - 3.3e-38 130.8 0.0 6e-38 129.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO54874.1 - 1.7e-25 88.7 0.0 1.5e-23 82.4 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AEO54874.1 - 6.1e-07 29.4 0.1 1.8e-06 27.8 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 AEO54874.1 - 0.012 14.6 0.1 0.088 11.8 0.0 2.0 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Cyclin PF08613.6 AEO54875.1 - 2.6e-13 50.6 0.8 3.9e-13 50.0 0.0 1.7 2 1 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 AEO54875.1 - 0.0093 15.5 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain CorA PF01544.13 AEO54876.1 - 3.3e-13 49.3 0.7 5.9e-13 48.5 0.5 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Ribosomal_S30 PF04758.9 AEO54878.1 - 1.5e-28 98.3 7.6 1.8e-28 98.0 5.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Pyrid_oxidase_2 PF13883.1 AEO54879.1 - 7.6e-42 142.9 0.0 1.3e-41 142.1 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Robl_LC7 PF03259.12 AEO54881.1 - 7.1e-11 41.5 0.1 4.3e-07 29.3 0.0 2.1 2 0 0 2 2 2 2 Roadblock/LC7 domain Ipi1_N PF12333.3 AEO54882.1 - 2.1e-27 95.0 0.0 5.6e-27 93.6 0.0 1.8 1 0 0 1 1 1 1 Rix1 complex component involved in 60S ribosome maturation HEAT_2 PF13646.1 AEO54882.1 - 0.063 13.5 0.3 0.15 12.3 0.2 1.7 1 1 0 1 1 1 0 HEAT repeats DEAD PF00270.24 AEO54883.1 - 1.1e-42 145.3 0.0 4.7e-42 143.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO54883.1 - 2.1e-19 69.1 1.4 2.6e-19 68.8 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 AEO54883.1 - 1.3e-06 27.4 0.0 2e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain SecA_DEAD PF07517.9 AEO54883.1 - 0.0051 16.1 0.1 0.086 12.1 0.0 2.0 2 0 0 2 2 2 1 SecA DEAD-like domain DUF1253 PF06862.7 AEO54883.1 - 0.014 13.8 0.0 0.69 8.2 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1253) Thioredoxin_8 PF13905.1 AEO54883.1 - 0.081 13.0 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like ResIII PF04851.10 AEO54883.1 - 0.086 12.6 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 AEO54883.1 - 0.1 12.5 0.0 0.23 11.4 0.0 1.6 2 0 0 2 2 2 0 Helicase C-terminal domain Acatn PF13000.2 AEO54884.1 - 1.7e-149 498.8 17.3 1.5e-74 251.5 5.4 3.0 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 Reticulon PF02453.12 AEO54884.1 - 0.96 9.0 5.8 0.09 12.3 0.5 1.9 2 0 0 2 2 2 0 Reticulon CENP-O PF09496.5 AEO54885.1 - 1.2e-22 79.9 0.0 2.1e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component MFS_1 PF07690.11 AEO54886.1 - 4e-42 144.1 31.9 1.5e-41 142.3 10.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO54886.1 - 1.4e-13 50.2 4.6 1.4e-13 50.2 3.2 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 AEO54886.1 - 9.5e-07 27.5 14.1 0.00029 19.3 5.2 2.7 1 1 1 3 3 3 2 MFS/sugar transport protein OATP PF03137.15 AEO54886.1 - 0.00046 18.3 3.3 0.0062 14.6 0.2 2.1 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family RNA_pol_Rpc4 PF05132.9 AEO54886.1 - 0.0043 17.0 2.2 0.0074 16.2 1.5 1.3 1 0 0 1 1 1 1 RNA polymerase III RPC4 TRI12 PF06609.8 AEO54886.1 - 0.0094 14.1 3.0 0.016 13.4 2.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Dicty_REP PF05086.7 AEO54886.1 - 0.22 9.2 0.8 0.28 8.8 0.5 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF1129 PF06570.6 AEO54886.1 - 1.2 8.3 4.8 1.4 8.1 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) PTCB-BRCT PF12738.2 AEO54887.1 - 3.5e-11 42.7 0.0 8e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 AEO54887.1 - 1.3e-10 41.2 0.0 2.7e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain fn3 PF00041.16 AEO54887.1 - 0.0007 19.6 0.0 0.0021 18.1 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain DUF3006 PF11213.3 AEO54887.1 - 0.003 17.2 0.0 0.0089 15.7 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) DFP PF04127.10 AEO54888.1 - 1.6e-14 53.9 0.0 2.5e-06 27.2 0.0 3.1 1 1 2 3 3 3 3 DNA / pantothenate metabolism flavoprotein eIF-1a PF01176.14 AEO54890.1 - 2.8e-27 93.9 0.2 4.1e-27 93.3 0.1 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 WH1 PF00568.18 AEO54891.1 - 2.2e-28 98.2 0.1 2.9e-28 97.7 0.1 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.15 AEO54891.1 - 0.00044 19.7 0.2 0.0011 18.5 0.1 1.7 1 0 0 1 1 1 1 WH2 motif ERCC4 PF02732.10 AEO54893.1 - 5.7e-25 87.7 0.0 1.9e-24 86.0 0.0 1.9 2 0 0 2 2 2 1 ERCC4 domain Glycoprotein_B PF00606.13 AEO54894.1 - 0.012 13.7 3.0 0.013 13.5 2.1 1.0 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B SMC_N PF02463.14 AEO54895.1 - 1.3e-16 60.5 20.6 3e-15 56.0 14.3 3.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 AEO54895.1 - 1.4e-12 48.3 20.0 1.4e-12 48.3 13.8 4.9 2 2 0 2 2 2 1 AAA domain AAA_21 PF13304.1 AEO54895.1 - 0.00027 20.9 0.0 0.00044 20.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 AEO54895.1 - 0.0023 17.4 0.0 0.0051 16.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 AEO54895.1 - 0.02 13.9 3.5 0.1 11.6 0.0 2.8 2 1 0 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 AEO54895.1 - 0.027 13.6 0.1 0.14 11.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA PF00004.24 AEO54895.1 - 0.081 13.1 3.0 0.26 11.4 0.0 3.4 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 AEO54895.1 - 4.7 6.5 11.9 0.61 9.4 0.0 3.8 3 1 0 3 3 3 0 AAA domain Pkinase PF00069.20 AEO54896.1 - 4.9e-75 252.0 0.0 9.7e-75 251.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO54896.1 - 7.1e-38 130.1 0.2 7e-36 123.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 AEO54896.1 - 4.1e-06 25.9 0.0 7.6e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 AEO54896.1 - 0.00085 18.4 0.0 0.002 17.2 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AEO54896.1 - 0.0015 18.2 0.4 0.0077 15.9 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 AEO54896.1 - 0.0024 17.4 0.2 0.0054 16.3 0.1 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Lyase_1 PF00206.15 AEO54897.1 - 5.4e-110 367.4 0.0 7.4e-110 366.9 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 AEO54897.1 - 5.2e-23 80.8 0.0 1.1e-22 79.8 0.0 1.6 1 0 0 1 1 1 1 Fumarase C C-terminus Malate_synthase PF01274.17 AEO54898.1 - 3e-237 787.8 0.0 3.3e-237 787.6 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Amidase PF01425.16 AEO54899.1 - 6.8e-86 288.8 0.7 1e-85 288.2 0.5 1.3 1 0 0 1 1 1 1 Amidase SEN1_N PF12726.2 AEO54900.1 - 6.8e-192 639.3 0.1 8.5e-192 639.0 0.1 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 AEO54900.1 - 5.1e-70 235.7 0.6 5.1e-70 235.7 0.4 2.1 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 AEO54900.1 - 4.4e-63 212.2 0.0 7.5e-63 211.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AEO54900.1 - 7.8e-12 44.7 0.2 2.5e-11 43.1 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 AEO54900.1 - 9e-09 35.1 0.1 4.9e-06 26.2 0.1 2.5 2 0 0 2 2 2 2 AAA domain UvrD-helicase PF00580.16 AEO54900.1 - 3.5e-06 26.5 2.4 0.0001 21.7 0.0 2.9 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.13 AEO54900.1 - 7.9e-06 25.5 0.5 0.013 15.0 0.0 3.4 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 AEO54900.1 - 0.023 14.1 0.0 0.066 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 AEO54900.1 - 0.042 14.1 0.1 0.042 14.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain ResIII PF04851.10 AEO54900.1 - 0.047 13.5 0.2 0.35 10.6 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit HhH-GPD PF00730.20 AEO54901.1 - 2.1e-08 34.4 0.0 5.4e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DNA_methylase PF00145.12 AEO54902.1 - 2.5e-36 125.4 0.0 6.5e-27 94.5 0.0 2.1 1 1 0 2 2 2 2 C-5 cytosine-specific DNA methylase EAF PF09816.4 AEO54903.1 - 3.5e-23 81.6 0.0 6.1e-23 80.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor Herpes_TAF50 PF03326.8 AEO54903.1 - 0.22 10.4 8.5 0.32 9.8 5.9 1.2 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) Glyco_hydro_76 PF03663.9 AEO54904.1 - 1.5e-149 498.4 10.7 1.9e-149 498.1 7.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 SOG2 PF10428.4 AEO54905.1 - 0.72 8.4 22.3 0.0083 14.8 8.1 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein IMD PF08397.6 AEO54907.1 - 0.19 11.0 0.8 6.2 6.0 0.1 2.1 2 0 0 2 2 2 0 IRSp53/MIM homology domain Abhydrolase_2 PF02230.11 AEO54908.1 - 1.8e-62 210.6 0.0 2.2e-62 210.3 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 AEO54908.1 - 1.1e-11 44.6 0.0 2.5e-11 43.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AEO54908.1 - 6.7e-08 32.6 0.0 3.8e-05 23.6 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family FSH1 PF03959.8 AEO54908.1 - 5.3e-05 22.7 0.0 0.00021 20.7 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.16 AEO54908.1 - 0.00018 20.7 0.2 0.0022 17.2 0.0 2.4 3 0 0 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 AEO54908.1 - 0.00066 19.3 0.0 0.044 13.3 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.13 AEO54908.1 - 0.0053 16.0 0.0 0.0082 15.4 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Cutinase PF01083.17 AEO54908.1 - 0.031 14.0 0.0 0.047 13.4 0.0 1.3 1 0 0 1 1 1 0 Cutinase AXE1 PF05448.7 AEO54908.1 - 0.15 10.5 0.1 0.25 9.8 0.1 1.4 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) LigB PF02900.13 AEO54909.1 - 4.9e-55 186.4 0.1 5.7e-55 186.2 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase TRI12 PF06609.8 AEO54910.1 - 3e-34 118.2 24.7 3.6e-34 117.9 17.1 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 AEO54910.1 - 1.5e-19 69.9 49.0 1.5e-19 69.9 34.0 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO54910.1 - 2.6e-09 36.1 36.3 8.4e-09 34.5 10.0 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter DUF4131 PF13567.1 AEO54910.1 - 0.055 12.8 0.4 0.055 12.8 0.3 4.5 4 1 1 5 5 5 0 Domain of unknown function (DUF4131) FAD_binding_8 PF08022.7 AEO54911.1 - 1.4e-14 53.8 0.1 5.4e-14 51.9 0.0 2.1 3 0 0 3 3 3 1 FAD-binding domain Ferric_reduct PF01794.14 AEO54911.1 - 2e-14 53.7 8.0 2e-14 53.7 5.6 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 AEO54911.1 - 1.7e-13 50.7 0.0 7.2e-09 35.7 0.0 2.4 2 0 0 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 AEO54911.1 - 8.6e-05 23.0 0.0 0.02 15.4 0.0 2.7 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain DAO PF01266.19 AEO54912.1 - 6.7e-36 123.9 1.0 9.7e-36 123.3 0.7 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 AEO54912.1 - 7.2e-05 23.1 0.0 0.038 14.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AEO54912.1 - 0.0012 18.8 0.0 0.0027 17.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 AEO54912.1 - 0.024 14.4 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 AEO54912.1 - 0.1 12.4 0.0 2.7 7.8 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.20 AEO54913.1 - 1.7e-32 112.6 4.6 2.3e-32 112.1 3.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO54913.1 - 1.1e-17 64.6 0.7 1.4e-17 64.2 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO54913.1 - 1.4e-14 54.1 3.3 2.1e-14 53.5 2.3 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 AEO54913.1 - 8.4e-05 22.1 0.2 0.00015 21.2 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 AEO54913.1 - 0.0001 22.3 1.8 0.0004 20.4 1.2 1.9 1 1 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 AEO54913.1 - 0.0032 17.4 0.0 0.011 15.6 0.0 1.8 2 0 0 2 2 2 1 TrkA-N domain Saccharop_dh PF03435.13 AEO54913.1 - 0.0054 15.7 0.1 0.0064 15.5 0.1 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase PP2C_2 PF13672.1 AEO54913.1 - 0.04 13.3 0.1 0.068 12.5 0.1 1.3 1 0 0 1 1 1 0 Protein phosphatase 2C Eno-Rase_NADH_b PF12242.3 AEO54913.1 - 0.044 13.5 0.3 0.098 12.4 0.2 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1995 PF09353.5 AEO54913.1 - 0.062 12.9 0.1 1.6 8.3 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF1995) ADH_zinc_N PF00107.21 AEO54913.1 - 0.081 12.4 0.2 0.21 11.1 0.0 1.9 2 0 0 2 2 2 0 Zinc-binding dehydrogenase F420_oxidored PF03807.12 AEO54913.1 - 0.087 13.2 0.3 0.29 11.5 0.1 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DUF1776 PF08643.5 AEO54913.1 - 0.095 11.8 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF1104 PF06518.6 AEO54913.1 - 0.1 12.7 0.2 0.39 10.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) CBFD_NFYB_HMF PF00808.18 AEO54914.1 - 2.1e-16 59.7 0.4 4.2e-16 58.7 0.3 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 AEO54914.1 - 0.00016 21.7 0.0 0.00032 20.7 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DNA_pol3_a_NII PF11490.3 AEO54914.1 - 0.093 12.3 2.6 0.14 11.8 1.8 1.2 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II Spidroin_MaSp PF11260.3 AEO54914.1 - 0.12 12.4 0.2 0.24 11.4 0.1 1.5 1 1 0 1 1 1 0 Major ampullate spidroin 1 and 2 zf-DHHC PF01529.15 AEO54916.1 - 7.4e-38 129.6 1.0 7.4e-38 129.6 0.7 2.0 1 1 1 2 2 2 1 DHHC palmitoyltransferase Yip1 PF04893.12 AEO54916.1 - 0.21 11.0 8.8 0.029 13.8 1.0 2.1 2 0 0 2 2 2 0 Yip1 domain Complex1_LYR_1 PF13232.1 AEO54918.1 - 4.7e-25 87.5 3.4 6.1e-25 87.2 2.3 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 AEO54918.1 - 3.9e-24 84.2 3.4 5.7e-24 83.6 2.4 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 AEO54918.1 - 0.0011 19.3 0.5 0.0013 19.1 0.4 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Fungal_trans PF04082.13 AEO54919.1 - 5.8e-12 45.0 0.3 1.5e-11 43.7 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO54919.1 - 0.017 15.0 7.5 0.037 13.9 5.2 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2141 PF09912.4 AEO54920.1 - 0.16 11.6 0.1 0.56 9.8 0.1 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2141) HEAT PF02985.17 AEO54921.1 - 5.8e-15 53.9 10.2 0.00048 19.9 0.0 10.2 12 0 0 12 12 12 3 HEAT repeat HEAT_2 PF13646.1 AEO54921.1 - 8.6e-14 51.5 13.4 3.1e-06 27.3 0.0 8.3 2 2 6 8 8 8 4 HEAT repeats HEAT_EZ PF13513.1 AEO54921.1 - 2.1e-13 50.3 7.8 7.1e-07 29.5 0.0 9.1 8 1 2 10 10 10 1 HEAT-like repeat IBN_N PF03810.14 AEO54921.1 - 6.7e-08 32.3 7.6 1.7e-07 31.0 2.0 3.8 4 0 0 4 4 4 1 Importin-beta N-terminal domain RIX1 PF08167.7 AEO54921.1 - 7.3e-05 22.4 0.5 0.28 10.8 0.0 4.4 2 1 1 4 4 4 2 rRNA processing/ribosome biogenesis CLASP_N PF12348.3 AEO54921.1 - 0.0001 21.7 4.3 1.6 8.0 0.1 4.9 4 2 3 7 7 7 3 CLASP N terminal Arm PF00514.18 AEO54921.1 - 0.0012 18.6 0.4 1.2 9.0 0.0 4.7 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Cse1 PF08506.5 AEO54921.1 - 0.0051 15.4 0.0 0.34 9.4 0.1 3.0 3 0 0 3 3 3 1 Cse1 HEAT_PBS PF03130.11 AEO54921.1 - 0.022 15.1 0.8 32 5.3 0.0 5.1 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat HMGL-like PF00682.14 AEO54922.1 - 1.8e-64 217.6 0.0 3.4e-64 216.7 0.0 1.4 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 AEO54922.1 - 5.2e-23 81.3 0.0 1.4e-22 79.9 0.0 1.8 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain NAD_binding_6 PF08030.7 AEO54923.1 - 7.7e-19 68.1 0.0 1.2e-16 60.9 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 AEO54923.1 - 7.7e-19 68.0 6.0 7.7e-19 68.0 4.1 2.7 2 1 1 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 AEO54923.1 - 1.3e-12 47.4 0.0 1e-11 44.6 0.0 2.1 1 1 0 1 1 1 1 FAD-binding domain DUF1690 PF07956.6 AEO54924.1 - 8.4e-31 106.8 4.8 1e-30 106.5 3.3 1.1 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) Mitofilin PF09731.4 AEO54924.1 - 0.012 14.3 7.7 0.015 13.9 5.3 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein PRTP PF01366.13 AEO54924.1 - 0.024 12.6 4.1 0.029 12.4 2.8 1.0 1 0 0 1 1 1 0 Herpesvirus processing and transport protein BRCA-2_helical PF09169.5 AEO54924.1 - 0.17 11.4 1.6 0.18 11.3 0.2 1.7 1 1 1 2 2 2 0 BRCA2, helical PAP_central PF04928.12 AEO54924.1 - 0.21 10.3 1.2 0.27 9.9 0.8 1.2 1 0 0 1 1 1 0 Poly(A) polymerase central domain DUF4611 PF15387.1 AEO54924.1 - 0.35 11.0 4.1 0.33 11.1 1.8 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4611) Docking PF08990.6 AEO54924.1 - 0.36 10.0 5.9 0.26 10.5 1.8 2.3 2 0 0 2 2 2 0 Erythronolide synthase docking DUF1640 PF07798.6 AEO54924.1 - 1.9 8.5 5.9 3.1 7.8 3.5 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1640) DUF1682 PF07946.9 AEO54924.1 - 2.9 6.6 8.4 3.8 6.2 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) TYW3 PF02676.9 AEO54925.1 - 1.7e-64 216.7 0.0 2.5e-64 216.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase TYW3 PAPS_reduct PF01507.14 AEO54926.1 - 1.1e-43 149.0 0.0 1.1e-43 149.0 0.0 1.4 2 0 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family Spt20 PF12090.3 AEO54926.1 - 0.026 13.8 1.6 0.049 12.9 1.1 1.4 1 0 0 1 1 1 0 Spt20 family RimM PF01782.13 AEO54926.1 - 0.041 13.8 1.7 0.19 11.6 0.0 2.4 2 0 0 2 2 2 0 RimM N-terminal domain Pro_CA PF00484.14 AEO54926.1 - 4.9 7.1 6.0 13 5.7 3.7 1.9 2 0 0 2 2 2 0 Carbonic anhydrase HAD PF12710.2 AEO54927.1 - 1.1e-17 64.8 0.0 1.6e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 AEO54927.1 - 3.5e-10 40.6 1.1 2.3e-08 34.7 0.8 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 AEO54927.1 - 9.2e-09 35.2 1.2 4.3e-08 33.0 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 AEO54927.1 - 4.2e-06 27.1 0.0 1.9e-05 24.9 0.0 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF705 PF05152.7 AEO54927.1 - 0.0011 18.0 0.1 0.0016 17.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF705) Put_Phosphatase PF06888.7 AEO54927.1 - 0.033 13.3 0.1 1.4 8.0 0.0 2.2 2 0 0 2 2 2 0 Putative Phosphatase SpoOE-like PF09388.5 AEO54927.1 - 0.11 11.9 0.3 0.55 9.7 0.1 2.0 2 0 0 2 2 2 0 Spo0E like sporulation regulatory protein Acid_PPase PF12689.2 AEO54927.1 - 0.14 11.8 0.0 0.33 10.5 0.0 1.6 2 0 0 2 2 2 0 Acid Phosphatase GTP_EFTU PF00009.22 AEO54928.1 - 4.4e-58 195.8 0.0 6.5e-58 195.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 AEO54928.1 - 1.2e-36 124.8 0.0 2.9e-36 123.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 AEO54928.1 - 1e-16 60.8 0.7 1e-16 60.8 0.5 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 AEO54928.1 - 0.00032 20.2 0.2 0.00083 18.9 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 AEO54928.1 - 0.00048 20.0 0.2 0.0017 18.2 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase SLS PF14611.1 AEO54929.1 - 3.5e-39 134.4 0.0 5.3e-39 133.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator DUF3090 PF11290.3 AEO54929.1 - 0.049 13.1 0.0 0.23 10.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3090) MAGE PF01454.14 AEO54930.1 - 9.5e-47 158.8 0.0 1.2e-46 158.5 0.0 1.1 1 0 0 1 1 1 1 MAGE family SF3b10 PF07189.6 AEO54931.1 - 3.3e-42 142.1 0.0 3.8e-42 141.9 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) zf-MYND PF01753.13 AEO54932.1 - 0.0003 20.6 18.1 0.01 15.7 3.5 3.3 3 0 0 3 3 3 2 MYND finger DUF329 PF03884.9 AEO54932.1 - 0.03 13.8 3.4 0.41 10.2 0.2 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF329) RPAP2_Rtr1 PF04181.8 AEO54932.1 - 0.054 13.5 5.0 4.5 7.4 0.3 2.9 2 0 0 2 2 2 0 Rtr1/RPAP2 family Metallothio_Pro PF02069.11 AEO54932.1 - 5.2 6.9 12.7 5 7.0 4.4 2.7 2 0 0 2 2 2 0 Prokaryotic metallothionein Septin PF00735.13 AEO54933.1 - 2.7e-31 108.6 0.0 6.3e-12 45.0 0.0 3.1 3 0 0 3 3 3 3 Septin FtsK_SpoIIIE PF01580.13 AEO54933.1 - 0.0023 17.4 0.0 0.0051 16.3 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_23 PF13476.1 AEO54933.1 - 0.0038 17.5 2.0 0.008 16.5 1.4 1.7 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 AEO54933.1 - 0.013 15.4 0.1 0.039 13.8 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase G-alpha PF00503.15 AEO54933.1 - 0.019 13.6 0.0 0.019 13.6 0.0 1.6 2 0 0 2 2 1 0 G-protein alpha subunit AAA_17 PF13207.1 AEO54933.1 - 0.023 15.4 0.0 0.078 13.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 AEO54933.1 - 0.032 14.7 0.1 0.093 13.2 0.0 1.9 2 1 0 2 2 1 0 Miro-like protein Dynamin_N PF00350.18 AEO54933.1 - 0.044 13.6 1.6 0.28 10.9 0.1 2.4 2 0 0 2 2 2 0 Dynamin family AAA_18 PF13238.1 AEO54933.1 - 0.063 13.5 0.1 0.23 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 AEO54933.1 - 0.079 12.3 0.0 7.1 6.0 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Pox_A32 PF04665.7 AEO54933.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein MobB PF03205.9 AEO54933.1 - 0.15 11.7 0.4 0.31 10.7 0.0 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B APH PF01636.18 AEO54934.1 - 0.00086 19.0 0.0 0.0014 18.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family ABC1 PF03109.11 AEO54934.1 - 0.0065 16.4 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 ABC1 family ABC1 PF03109.11 AEO54935.1 - 4.1e-13 49.3 0.0 7.3e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 ABC1 family SUR7 PF06687.7 AEO54937.1 - 9.8e-28 97.1 13.6 1.2e-27 96.8 9.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family YesK PF14150.1 AEO54937.1 - 0.047 13.7 9.6 1.3 9.1 0.7 2.4 2 0 0 2 2 2 0 YesK-like protein NfeD PF01957.13 AEO54937.1 - 2 8.5 9.9 0.069 13.2 2.2 2.0 2 1 0 2 2 2 0 NfeD-like C-terminal, partner-binding DUF2569 PF10754.4 AEO54937.1 - 3.7 7.7 12.0 0.043 14.0 2.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) 7TMR-DISM_7TM PF07695.6 AEO54937.1 - 6.1 6.4 18.8 0.5 10.0 8.4 1.9 2 0 0 2 2 2 0 7TM diverse intracellular signalling bZIP_1 PF00170.16 AEO54939.1 - 1.4e-06 28.1 18.0 2.2e-06 27.5 12.5 1.2 1 0 0 1 1 1 1 bZIP transcription factor PAP1 PF08601.5 AEO54939.1 - 0.00013 21.7 1.5 0.0015 18.2 0.2 2.7 1 1 1 2 2 2 1 Transcription factor PAP1 ERM PF00769.14 AEO54939.1 - 0.0013 18.3 6.2 0.0018 17.8 4.3 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family ADIP PF11559.3 AEO54939.1 - 0.014 15.2 10.0 0.44 10.4 7.8 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Vac_Fusion PF02346.11 AEO54939.1 - 0.017 14.5 2.3 0.027 13.8 1.6 1.3 1 0 0 1 1 1 0 Chordopoxvirus fusion protein bZIP_Maf PF03131.12 AEO54939.1 - 0.017 15.4 13.8 0.025 14.8 9.6 1.2 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF972 PF06156.8 AEO54939.1 - 0.027 14.8 0.7 0.051 13.9 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Snapin_Pallidin PF14712.1 AEO54939.1 - 0.04 14.2 1.8 0.068 13.4 1.2 1.3 1 0 0 1 1 1 0 Snapin/Pallidin bZIP_2 PF07716.10 AEO54939.1 - 0.049 13.4 22.5 0.54 10.1 14.2 2.2 1 1 1 2 2 2 0 Basic region leucine zipper Herpes_UL25 PF01499.11 AEO54939.1 - 0.054 11.8 5.2 0.076 11.3 3.6 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF724 PF05266.9 AEO54939.1 - 0.087 12.4 4.0 0.12 11.9 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) V_ATPase_I PF01496.14 AEO54939.1 - 0.089 10.6 0.6 0.11 10.3 0.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PA26 PF04636.8 AEO54939.1 - 0.15 10.7 0.4 0.17 10.5 0.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Glutaredoxin2_C PF04399.8 AEO54939.1 - 0.15 11.6 1.9 0.23 11.0 1.3 1.2 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain IncA PF04156.9 AEO54939.1 - 0.57 9.7 3.9 0.81 9.2 2.7 1.2 1 0 0 1 1 1 0 IncA protein NAM-associated PF14303.1 AEO54939.1 - 0.67 10.2 7.5 1 9.6 5.2 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain GvpL_GvpF PF06386.6 AEO54939.1 - 1.9 7.9 7.3 3.3 7.2 4.8 1.5 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF APG6 PF04111.7 AEO54939.1 - 5.9 5.8 8.2 8 5.4 5.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 CDP-OH_P_transf PF01066.16 AEO54940.1 - 9.4e-16 57.9 3.2 9.4e-16 57.9 2.2 2.6 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Adaptin_N PF01602.15 AEO54941.1 - 8.2e-117 390.6 0.9 1e-116 390.3 0.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 AEO54941.1 - 2.9e-56 189.4 4.3 6.1e-56 188.4 3.0 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 AEO54941.1 - 1.3e-14 54.1 2.0 3.4e-05 24.0 0.1 6.1 2 1 4 6 6 6 4 HEAT repeats HEAT_PBS PF03130.11 AEO54941.1 - 0.0002 21.5 0.3 1.2 9.7 0.0 4.6 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat CLASP_N PF12348.3 AEO54941.1 - 0.00059 19.2 1.5 0.015 14.6 0.1 2.7 3 0 0 3 3 3 1 CLASP N terminal MRP-S35 PF10246.4 AEO54941.1 - 0.015 15.2 0.0 0.31 11.0 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial ribosomal protein MRP-S35 HEAT PF02985.17 AEO54941.1 - 0.26 11.4 8.6 1.9 8.8 0.2 4.7 5 0 0 5 5 5 0 HEAT repeat HEAT_EZ PF13513.1 AEO54941.1 - 0.33 11.4 3.4 1.1 9.8 0.7 3.1 2 0 0 2 2 2 0 HEAT-like repeat Myb_DNA-bind_6 PF13921.1 AEO54942.1 - 0.002 18.1 0.1 0.0056 16.7 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain UPF0016 PF01169.14 AEO54943.1 - 2e-41 139.9 25.2 5e-22 77.8 5.2 2.3 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 DUF3154 PF11351.3 AEO54943.1 - 0.33 10.7 2.2 0.97 9.1 1.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3154) EI24 PF07264.6 AEO54944.1 - 2.5e-06 27.0 1.9 6.5e-06 25.7 1.3 1.8 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) ATP-sulfurylase PF01747.12 AEO54946.1 - 2.4e-89 298.2 0.1 3.4e-89 297.8 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 AEO54946.1 - 1.1e-60 203.7 0.0 1.7e-60 203.2 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 AEO54946.1 - 4e-52 175.8 0.0 6.5e-52 175.1 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain AAA_33 PF13671.1 AEO54946.1 - 0.0006 19.7 0.3 0.0017 18.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 AEO54946.1 - 0.019 14.1 0.0 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 CPT PF07931.7 AEO54946.1 - 0.041 13.5 0.0 0.18 11.4 0.0 1.9 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_17 PF13207.1 AEO54946.1 - 0.047 14.5 0.0 0.6 10.9 0.0 2.5 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.1 AEO54946.1 - 0.1 12.9 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain TRP PF06011.7 AEO54948.1 - 1.6e-85 287.3 8.0 2.2e-85 286.8 5.6 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 AEO54948.1 - 4.8e-24 85.0 0.0 7.7e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 ML-like domain DUF1705 PF08019.7 AEO54948.1 - 3.4 7.1 13.1 0.31 10.5 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1705) UPF0560 PF10577.4 AEO54948.1 - 5.8 5.0 7.1 8.9 4.4 4.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 BAF1_ABF1 PF04684.8 AEO54948.1 - 8 5.1 9.7 12 4.6 6.7 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Dioxygenase_C PF00775.16 AEO54949.1 - 2.4e-42 144.2 0.0 3.2e-42 143.8 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 AEO54949.1 - 4.1e-17 61.9 0.0 6e-17 61.3 0.0 1.2 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 AEO54949.1 - 1.5e-05 24.9 0.0 4.1e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF824 PF05688.6 AEO54949.1 - 0.15 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF824) AdoMet_MTase PF07757.8 AEO54950.1 - 4.2e-37 126.6 0.0 7.1e-37 125.9 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.1 AEO54950.1 - 0.0079 15.9 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO54950.1 - 0.013 16.0 0.0 0.025 15.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 AEO54950.1 - 0.041 13.5 0.2 0.57 9.8 0.2 2.2 1 1 0 1 1 1 0 Methyltransferase domain SUI1 PF01253.17 AEO54951.1 - 1.6e-29 101.4 2.1 2.2e-29 101.0 1.5 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 Cas_Csa5 PF09702.5 AEO54951.1 - 0.0035 17.3 0.1 0.005 16.8 0.1 1.2 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Csa5) Put_Phosphatase PF06888.7 AEO54951.1 - 0.062 12.4 0.0 0.075 12.1 0.0 1.1 1 0 0 1 1 1 0 Putative Phosphatase DUF2575 PF10837.3 AEO54951.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2575) EOS1 PF12326.3 AEO54952.1 - 3.8e-28 97.9 11.8 1.8e-23 82.8 3.3 2.2 1 1 1 2 2 2 2 N-glycosylation protein Tim44 PF04280.10 AEO54953.1 - 7.7e-05 22.7 0.0 0.00015 21.7 0.0 1.5 1 0 0 1 1 1 1 Tim44-like domain MBA1 PF07961.6 AEO54953.1 - 0.00047 19.0 0.0 0.00065 18.6 0.0 1.2 1 0 0 1 1 1 1 MBA1-like protein SSF PF00474.12 AEO54954.1 - 1.1e-05 24.2 29.0 8.8e-05 21.3 20.1 2.1 1 1 0 1 1 1 1 Sodium:solute symporter family RRM_1 PF00076.17 AEO54955.1 - 5.8e-21 73.9 0.2 3.5e-11 42.5 0.1 3.6 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO54955.1 - 1.9e-13 50.1 0.8 3.1e-08 33.4 0.1 3.3 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO54955.1 - 4.6e-13 48.7 0.1 5.5e-06 26.1 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 AEO54955.1 - 0.06 13.0 0.1 14 5.5 0.0 2.6 2 0 0 2 2 2 0 Limkain b1 CIA30 PF08547.7 AEO54956.1 - 1.2e-45 155.1 0.0 1.8e-45 154.6 0.0 1.2 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) CBM_11 PF03425.8 AEO54956.1 - 0.059 13.0 0.2 0.16 11.6 0.0 1.7 2 0 0 2 2 2 0 Carbohydrate binding domain (family 11) JmjC PF02373.17 AEO54958.1 - 4.4e-18 65.6 0.0 8.3e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase SET PF00856.23 AEO54958.1 - 4.4e-05 23.8 0.0 0.0001 22.6 0.0 1.6 1 0 0 1 1 1 1 SET domain ATG16 PF08614.6 AEO54959.1 - 0.0016 18.3 4.6 0.0022 17.8 2.2 1.9 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.4 AEO54959.1 - 0.022 14.6 8.7 0.33 10.8 1.6 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cluap1 PF10234.4 AEO54959.1 - 0.027 13.6 1.3 0.049 12.8 0.9 1.5 1 0 0 1 1 1 0 Clusterin-associated protein-1 Spc7 PF08317.6 AEO54959.1 - 0.21 10.2 3.0 0.41 9.2 1.3 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein IncA PF04156.9 AEO54959.1 - 0.27 10.8 11.2 0.062 12.8 2.2 2.2 2 0 0 2 2 2 0 IncA protein Lge1 PF11488.3 AEO54959.1 - 0.28 11.3 1.3 15 5.8 0.1 2.7 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 Apt1 PF10351.4 AEO54959.1 - 0.3 9.9 0.8 0.4 9.4 0.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain CCDC155 PF14662.1 AEO54959.1 - 0.8 9.2 9.5 4.1 6.9 1.3 2.4 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 DUF972 PF06156.8 AEO54959.1 - 1 9.7 3.9 16 5.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF972) CP12 PF02672.10 AEO54959.1 - 1.5 9.3 8.2 2.3 8.7 0.3 3.3 4 0 0 4 4 3 0 CP12 domain Striatin PF08232.7 AEO54959.1 - 1.8 8.8 7.3 10 6.4 5.0 2.3 1 1 0 1 1 1 0 Striatin family MscS_porin PF12795.2 AEO54959.1 - 2 7.6 11.9 7.4 5.8 8.3 1.9 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain GAS PF13851.1 AEO54959.1 - 4 6.5 7.2 3.3 6.8 1.0 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Macoilin PF09726.4 AEO54959.1 - 7.3 4.7 8.4 13 3.9 5.8 1.4 1 1 0 1 1 1 0 Transmembrane protein ADIP PF11559.3 AEO54959.1 - 8.8 6.2 14.8 0.7 9.7 0.7 3.1 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Thioredoxin PF00085.15 AEO54960.1 - 5.3e-07 29.2 0.0 7.4e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 AEO54960.1 - 0.0036 16.8 0.0 0.0048 16.4 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin_2 PF13098.1 AEO54960.1 - 0.09 12.9 0.0 0.98 9.6 0.0 2.1 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_9 PF14595.1 AEO54960.1 - 0.13 11.7 0.0 0.23 11.0 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin MFS_1 PF07690.11 AEO54961.1 - 9.4e-44 149.5 29.5 1e-31 109.9 5.9 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO54961.1 - 8.9e-12 44.3 13.7 8.9e-12 44.3 9.5 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 AEO54961.1 - 0.00081 17.7 3.3 0.0016 16.7 2.3 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2348 PF09807.4 AEO54962.1 - 2e-06 27.0 0.0 0.0042 16.2 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2348) Ribosomal_L37e PF01907.14 AEO54963.1 - 2e-26 91.5 12.1 3.1e-26 90.9 8.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 AEO54963.1 - 0.0011 18.7 1.0 0.0015 18.3 0.7 1.3 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.1 AEO54963.1 - 0.0088 15.2 1.1 0.016 14.4 0.8 1.4 1 0 0 1 1 1 1 zinc-ribbon domain HypA PF01155.14 AEO54963.1 - 0.051 13.2 0.6 0.069 12.8 0.4 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family DUF1462 PF07315.6 AEO54963.1 - 0.12 12.3 0.1 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) Ribosomal_S14 PF00253.16 AEO54963.1 - 0.32 10.4 9.6 0.55 9.6 1.0 2.7 1 1 1 2 2 2 0 Ribosomal protein S14p/S29e zf-C3HC4 PF00097.20 AEO54963.1 - 0.33 10.6 3.7 0.54 9.9 2.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-NADH-PPase PF09297.6 AEO54963.1 - 4.6 6.8 7.7 24 4.5 5.3 2.0 1 1 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain tRNA-synt_1 PF00133.17 AEO54964.1 - 4.8e-225 748.1 0.0 4.3e-224 744.9 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 AEO54964.1 - 4.5e-36 123.8 0.0 1.4e-35 122.3 0.0 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 AEO54964.1 - 1.8e-16 59.8 0.1 0.00037 19.2 0.0 4.9 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 AEO54964.1 - 6.4e-13 48.4 0.0 6.8e-08 32.0 0.0 2.8 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 AEO54964.1 - 0.0035 16.5 0.1 0.023 13.8 0.0 2.3 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain Fusion_gly PF00523.13 AEO54964.1 - 0.087 10.8 0.2 0.13 10.3 0.1 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0 zf-RING_2 PF13639.1 AEO54965.1 - 1.4e-13 50.4 5.5 2.2e-13 49.8 3.8 1.3 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 AEO54965.1 - 2.7e-10 39.8 0.0 5.7e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.1 AEO54965.1 - 1.4e-09 37.7 5.4 2.3e-09 37.1 3.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 AEO54965.1 - 9.6e-09 35.2 1.9 1.8e-08 34.3 1.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 AEO54965.1 - 1.5e-08 34.1 3.4 2.4e-08 33.5 2.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AEO54965.1 - 4.5e-08 32.6 3.7 6.7e-08 32.0 2.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO54965.1 - 2.8e-07 30.1 3.1 4.3e-07 29.5 2.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 AEO54965.1 - 0.00067 19.4 0.9 0.0013 18.5 0.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 AEO54965.1 - 0.048 13.5 3.5 0.15 11.9 2.5 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 AEO54965.1 - 0.066 13.1 2.8 0.22 11.5 1.9 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 AEO54965.1 - 0.11 12.5 3.9 0.23 11.5 2.7 1.6 1 0 0 1 1 1 0 RING-variant domain zf-RING_UBOX PF13445.1 AEO54965.1 - 0.11 12.2 2.8 0.26 11.0 1.9 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Baculo_RING PF05883.6 AEO54965.1 - 0.27 11.0 0.4 0.46 10.3 0.3 1.3 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-RING_4 PF14570.1 AEO54965.1 - 0.78 9.3 3.1 1.4 8.5 2.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 AEO54965.1 - 1.4 8.9 3.4 2.8 8.0 2.4 1.5 1 0 0 1 1 1 0 RING-like domain Apc5 PF12862.2 AEO54966.1 - 5.4e-30 103.0 1.7 5.4e-30 103.0 1.1 2.3 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 5 TPR_14 PF13428.1 AEO54966.1 - 0.00018 21.8 20.9 0.64 10.8 0.2 8.3 5 2 3 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.1 AEO54966.1 - 0.00039 20.2 17.5 0.91 9.5 1.6 5.2 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_21 PF09976.4 AEO54966.1 - 2.6 7.9 9.1 45 3.9 0.1 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat COX6A PF02046.10 AEO54967.1 - 1.6e-46 157.0 2.9 1.8e-46 156.8 2.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Exo_endo_phos PF03372.18 AEO54968.1 - 1.5e-18 67.6 0.0 2.3e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 AEO54968.1 - 1.6e-17 63.1 0.0 7.9e-17 60.9 0.0 2.1 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase zf-GRF PF06839.7 AEO54968.1 - 1.1e-05 25.2 1.2 2.9e-05 23.9 0.8 1.8 1 0 0 1 1 1 1 GRF zinc finger HMG_box PF00505.14 AEO54969.1 - 8.4e-20 70.8 0.4 1.3e-19 70.2 0.3 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box YojJ PF10372.4 AEO54970.1 - 0.1 12.5 0.0 13 5.6 0.0 2.4 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus MAT_Alpha1 PF04769.7 AEO54971.1 - 5e-35 120.6 0.0 8.1e-35 119.9 0.0 1.3 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 PBP_like PF12727.2 AEO54971.1 - 0.11 11.3 0.1 2.7 6.8 0.0 2.6 1 1 1 3 3 3 0 PBP superfamily domain YadA_anchor PF03895.10 AEO54971.1 - 0.46 10.5 4.3 0.25 11.3 1.0 1.9 2 0 0 2 2 2 0 YadA-like C-terminal region ANTH PF07651.11 AEO54972.1 - 1.5e-81 273.2 2.3 1.8e-81 272.9 0.0 2.4 3 0 0 3 3 3 1 ANTH domain I_LWEQ PF01608.12 AEO54972.1 - 5.7e-64 214.6 8.2 5.7e-64 214.6 5.7 5.7 5 2 2 7 7 7 1 I/LWEQ domain ENTH PF01417.15 AEO54972.1 - 0.0002 21.2 0.0 0.00077 19.3 0.0 2.1 1 0 0 1 1 1 1 ENTH domain Reo_sigmaC PF04582.7 AEO54972.1 - 0.21 10.7 13.3 0.17 10.9 2.5 3.6 2 1 1 3 3 3 0 Reovirus sigma C capsid protein Autophagy_N PF03986.8 AEO54973.1 - 6e-45 152.5 0.7 8e-45 152.1 0.0 1.5 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 AEO54973.1 - 3.2e-23 81.6 1.2 1.7e-22 79.3 0.2 2.3 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 AEO54973.1 - 1.8e-14 52.4 0.5 3.3e-14 51.6 0.3 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal zf-C3HC4_3 PF13920.1 AEO54974.1 - 4.9e-08 32.5 3.7 7.8e-08 31.8 2.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.19 AEO54974.1 - 8.9e-08 31.6 1.9 1.9e-07 30.6 1.3 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_2 PF13923.1 AEO54974.1 - 2.7e-07 30.4 8.0 4.8e-07 29.7 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AEO54974.1 - 1.4e-06 27.8 4.8 2.6e-06 26.9 3.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AEO54974.1 - 1.8e-06 27.6 5.7 3e-06 26.9 4.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 AEO54974.1 - 1.9e-06 27.4 5.6 3.3e-06 26.7 3.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 AEO54974.1 - 0.00074 19.1 1.2 0.0021 17.7 0.8 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 AEO54974.1 - 0.019 14.8 6.4 0.042 13.7 4.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING VirC1 PF07015.6 AEO54974.1 - 0.16 11.0 0.1 0.27 10.2 0.1 1.3 1 0 0 1 1 1 0 VirC1 protein Mcp5_PH PF12814.2 AEO54975.1 - 2.4e-43 146.9 0.8 4e-43 146.2 0.0 1.8 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology DUF1202 PF06717.6 AEO54975.1 - 3.7 6.7 8.7 0.064 12.5 1.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1202) DNA_pol_B PF00136.16 AEO54976.1 - 7.1e-95 318.5 0.0 1e-94 318.0 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 AEO54976.1 - 2.3e-21 75.9 0.0 2e-10 40.0 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 AEO54976.1 - 6.4e-18 64.5 2.1 1.3e-17 63.5 1.4 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta XkdW PF09636.5 AEO54976.1 - 0.032 14.1 0.2 0.1 12.5 0.1 1.8 1 0 0 1 1 1 0 XkdW protein Slu7 PF11708.3 AEO54977.1 - 3.4e-68 229.9 13.6 5.1e-68 229.3 9.4 1.3 1 0 0 1 1 1 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 AEO54977.1 - 0.00019 21.0 0.2 0.0004 19.9 0.1 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 AEO54977.1 - 0.00073 19.3 3.2 0.0012 18.6 2.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 AEO54977.1 - 0.078 12.6 4.0 0.21 11.2 2.8 1.7 1 0 0 1 1 1 0 Zinc knuckle SapC PF07277.6 AEO54977.1 - 0.095 11.9 0.0 1.2 8.4 0.0 2.1 2 0 0 2 2 2 0 SapC Ribosomal_S4 PF00163.14 AEO54978.1 - 5.7e-28 97.1 1.8 6.6e-28 96.9 0.6 1.6 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 AEO54978.1 - 3.8e-14 51.8 1.5 3.8e-14 51.8 1.1 2.3 3 0 0 3 3 3 1 S4 domain Ribosomal_L21e PF01157.13 AEO54979.1 - 5.9e-39 131.8 6.2 7.7e-39 131.5 4.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L21e DUF3865 PF12981.2 AEO54979.1 - 0.12 12.0 0.1 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3865) DUF2404 PF10296.4 AEO54980.1 - 2e-33 114.3 0.0 1.5e-32 111.5 0.0 2.3 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) DUF1179 PF06678.6 AEO54981.1 - 0.86 9.9 5.3 0.69 10.2 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1179) Fer4 PF00037.22 AEO54981.1 - 8.7 6.1 12.1 0.64 9.7 0.8 3.8 3 0 0 3 3 3 0 4Fe-4S binding domain ISN1 PF06437.6 AEO54982.1 - 1.2e-191 636.7 0.0 1.4e-191 636.6 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase PV-1 PF06637.6 AEO54982.1 - 0.1 11.1 0.0 0.16 10.4 0.0 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Mitofilin PF09731.4 AEO54983.1 - 0.027 13.1 5.7 0.48 9.0 1.1 2.6 3 0 0 3 3 3 0 Mitochondrial inner membrane protein Pkinase PF00069.20 AEO54984.1 - 1e-54 185.4 0.0 1.5e-54 184.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO54984.1 - 4.1e-26 91.5 0.1 1.9e-25 89.4 0.1 1.9 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO54984.1 - 0.098 11.5 0.0 0.22 10.4 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 AEO54984.1 - 0.14 11.1 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cse1 PF08506.5 AEO54985.1 - 5.5e-08 31.7 0.1 2.1e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 Cse1 Xpo1 PF08389.7 AEO54985.1 - 1e-07 31.9 3.3 3.3e-06 27.0 0.2 4.1 4 0 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 AEO54985.1 - 0.0052 16.6 4.6 17 5.4 0.0 5.1 5 0 0 5 5 5 2 Importin-beta N-terminal domain DUF2435 PF10363.4 AEO54985.1 - 0.013 15.3 0.4 0.046 13.6 0.3 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2435) IMS PF00817.15 AEO54987.1 - 2.4e-22 79.3 0.0 4.4e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 AEO54987.1 - 2.5e-14 53.3 0.0 5.2e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 AEO54987.1 - 0.0072 16.3 0.0 0.016 15.2 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif zf-FPG_IleRS PF06827.9 AEO54987.1 - 0.12 12.0 0.1 0.28 10.8 0.1 1.7 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS zf-DHHC PF01529.15 AEO54988.1 - 7.3e-30 103.6 5.4 7.3e-30 103.6 3.7 2.4 1 1 1 2 2 2 1 DHHC palmitoyltransferase DUF2567 PF10821.3 AEO54988.1 - 0.016 14.7 1.6 0.027 13.9 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2567) SET PF00856.23 AEO54989.1 - 2.4e-19 70.2 0.8 2.4e-19 70.2 0.5 2.9 3 1 0 3 3 3 1 SET domain Cellulose_synt PF03552.9 AEO54989.1 - 6.9 4.8 9.2 12 3.9 6.4 1.3 1 0 0 1 1 1 0 Cellulose synthase LSM PF01423.17 AEO54990.1 - 1e-17 63.4 0.2 1.3e-17 63.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain Pkinase PF00069.20 AEO54991.1 - 2.2e-07 30.3 0.0 3.6e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO54991.1 - 0.063 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase IDEAL PF08858.5 AEO54991.1 - 7.4 6.1 6.3 1.4 8.4 1.0 2.3 2 0 0 2 2 2 0 IDEAL domain UBA_4 PF14555.1 AEO54992.1 - 2.7e-11 42.8 0.0 5.5e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 AEO54992.1 - 0.019 15.0 0.0 0.12 12.4 0.0 2.1 2 0 0 2 2 2 0 UBX domain SUFU_C PF12470.3 AEO54992.1 - 0.11 12.1 0.1 0.16 11.5 0.1 1.2 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain OmpH PF03938.9 AEO54992.1 - 5.7 6.8 11.0 33 4.3 5.7 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) GAT PF03127.9 AEO54993.1 - 5.5e-18 64.8 0.4 1.1e-17 63.8 0.1 1.6 2 0 0 2 2 2 1 GAT domain VHS PF00790.14 AEO54993.1 - 0.0069 16.0 0.0 0.017 14.7 0.0 1.7 1 0 0 1 1 1 1 VHS domain GCOM2 PF15328.1 AEO54994.1 - 0.0011 18.7 3.0 0.0029 17.4 1.2 1.9 2 0 0 2 2 2 1 Putative GRINL1B complex locus protein 2 ADIP PF11559.3 AEO54994.1 - 0.041 13.7 11.6 1 9.2 0.0 2.8 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.4 AEO54994.1 - 0.075 12.8 8.7 0.079 12.8 1.0 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CAGE1 PF15066.1 AEO54994.1 - 0.075 11.4 2.3 0.15 10.4 1.6 1.4 1 0 0 1 1 1 0 Cancer-associated gene protein 1 family TBPIP PF07106.8 AEO54994.1 - 0.12 11.8 8.8 0.87 9.1 2.0 2.3 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF972 PF06156.8 AEO54994.1 - 0.22 11.8 4.5 2.9 8.2 1.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DivIC PF04977.10 AEO54994.1 - 0.34 10.4 11.8 0.28 10.7 4.3 2.4 2 0 0 2 2 2 0 Septum formation initiator Spc24 PF08286.6 AEO54994.1 - 0.42 10.3 5.3 3.2 7.4 0.0 2.5 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 IncA PF04156.9 AEO54994.1 - 0.64 9.5 8.1 8.2 5.9 0.1 2.3 2 0 0 2 2 2 0 IncA protein 5_3_exonuc PF01367.15 AEO54994.1 - 0.67 10.2 2.8 1.4 9.2 1.2 2.0 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold MerR_2 PF13591.1 AEO54994.1 - 1.9 8.1 7.5 0.12 12.0 0.8 2.3 2 0 0 2 2 2 0 MerR HTH family regulatory protein DUF2802 PF10975.3 AEO54994.1 - 3 7.6 7.0 1.4 8.6 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) Spc7 PF08317.6 AEO54994.1 - 3.9 6.0 9.1 4.9 5.7 0.2 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein SlyX PF04102.7 AEO54994.1 - 7.6 6.9 13.3 13 6.1 0.2 3.3 3 0 0 3 3 3 0 SlyX Prefoldin_2 PF01920.15 AEO54994.1 - 8.4 6.2 11.8 4.3 7.1 4.0 2.5 2 0 0 2 2 2 0 Prefoldin subunit ADH_zinc_N PF00107.21 AEO54995.1 - 1.9e-14 53.3 0.0 3.5e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 AEO54995.1 - 1.3e-12 48.7 0.0 3.7e-12 47.2 0.0 1.8 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AEO54995.1 - 6.5e-06 25.8 0.3 0.00017 21.3 0.1 2.5 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 AEO54995.1 - 0.012 15.5 1.0 0.024 14.6 0.7 1.4 1 0 0 1 1 1 0 NADH(P)-binding Pec_lyase_C PF00544.14 AEO54996.1 - 2.6e-42 144.5 2.9 3.9e-42 144.0 2.0 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 AEO54996.1 - 0.005 16.6 8.5 0.29 10.8 5.8 2.3 1 1 0 1 1 1 1 Right handed beta helix region BTB PF00651.26 AEO54997.1 - 1.8e-12 47.2 0.0 4.3e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain GvpG PF05120.7 AEO54997.1 - 0.057 13.2 0.1 0.14 11.9 0.1 1.6 1 0 0 1 1 1 0 Gas vesicle protein G RNA_pol_Rpb2_4 PF04566.8 AEO54997.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 4 APH PF01636.18 AEO54998.1 - 8.2e-15 55.1 0.1 1.6e-09 37.8 0.0 2.1 2 0 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 AEO54998.1 - 3.4e-09 36.5 0.0 5.4e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 AEO54998.1 - 0.0031 16.5 0.0 0.024 13.6 0.0 1.9 2 0 0 2 2 2 1 Fructosamine kinase Pribosyltran_N PF13793.1 AEO55000.1 - 8.6e-43 144.7 0.8 8.9e-42 141.5 0.1 2.4 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 AEO55000.1 - 2.8e-40 138.0 4.0 6.9e-36 123.7 0.5 2.5 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 AEO55000.1 - 6.6e-13 48.4 0.7 1.8e-12 47.0 0.2 1.9 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 AEO55000.1 - 0.0053 15.9 0.5 0.011 14.9 0.3 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Chlorosome_CsmC PF11098.3 AEO55000.1 - 0.052 13.2 1.7 0.11 12.2 1.2 1.5 1 0 0 1 1 1 0 Chlorosome envelope protein C DUF218 PF02698.12 AEO55000.1 - 0.1 12.0 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 DUF218 domain AF2331-like PF14556.1 AEO55000.1 - 0.19 12.1 0.7 11 6.4 0.0 2.9 3 0 0 3 3 3 0 AF2331-like DSPc PF00782.15 AEO55001.1 - 8.5e-10 38.3 0.0 1.5e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 AEO55001.1 - 0.0089 15.3 0.1 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 AEO55001.1 - 0.017 15.3 0.1 0.029 14.6 0.1 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.1 AEO55001.1 - 0.24 11.4 0.1 0.44 10.5 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate UPF0121 PF03661.8 AEO55002.1 - 3e-12 46.2 2.0 4.4e-12 45.7 1.4 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Rhodanese PF00581.15 AEO55003.1 - 5.8e-16 58.8 0.1 9.9e-15 54.8 0.1 2.0 1 1 0 1 1 1 1 Rhodanese-like domain PAT1 PF09770.4 AEO55004.1 - 0.14 10.3 5.5 0.22 9.7 3.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Sporozoite_P67 PF05642.6 AEO55004.1 - 0.15 9.9 2.4 0.16 9.8 0.9 1.5 2 0 0 2 2 2 0 Sporozoite P67 surface antigen DUF4611 PF15387.1 AEO55004.1 - 2.2 8.5 7.2 7.5 6.7 5.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) SDA1 PF05285.7 AEO55004.1 - 2.9 7.0 10.2 0.053 12.7 2.5 1.4 2 0 0 2 2 2 0 SDA1 PBP1_TM PF14812.1 AEO55004.1 - 3.2 8.1 15.5 5.6 7.3 3.4 3.2 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.5 AEO55005.1 - 0.0053 16.9 1.5 0.0058 16.8 1.0 1.1 1 0 0 1 1 1 1 Centromere protein B dimerisation domain PBP1_TM PF14812.1 AEO55005.1 - 0.012 15.8 0.0 0.013 15.7 0.0 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sporozoite_P67 PF05642.6 AEO55005.1 - 0.064 11.1 3.5 0.067 11.0 2.4 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ATG27 PF09451.5 AEO55005.1 - 0.074 12.2 0.2 0.067 12.4 0.1 1.0 1 0 0 1 1 1 0 Autophagy-related protein 27 Sigma70_ner PF04546.8 AEO55005.1 - 0.18 11.4 3.4 0.19 11.3 2.3 1.0 1 0 0 1 1 1 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 AEO55005.1 - 0.48 9.9 2.7 0.5 9.8 1.8 1.1 1 0 0 1 1 1 0 Nucleoplasmin MRI PF15325.1 AEO55005.1 - 0.51 11.3 2.5 0.64 11.0 1.7 1.2 1 0 0 1 1 1 0 Modulator of retrovirus infection DUF4611 PF15387.1 AEO55005.1 - 0.91 9.7 5.0 1 9.5 3.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) NOA36 PF06524.7 AEO55005.1 - 2.3 7.4 7.3 2.5 7.2 5.1 1.0 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.4 AEO55005.1 - 3.1 6.4 9.0 3.3 6.3 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CobT PF06213.7 AEO55005.1 - 4.5 6.3 8.6 5.2 6.1 5.9 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.9 AEO55005.1 - 4.7 5.1 5.7 4.7 5.1 4.0 1.0 1 0 0 1 1 1 0 CDC45-like protein zf-C2H2 PF00096.21 AEO55007.1 - 0.0068 16.6 0.7 0.02 15.2 0.5 1.9 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AEO55007.1 - 0.03 14.6 0.1 0.083 13.2 0.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger PGC7_Stella PF15549.1 AEO55007.1 - 0.55 10.2 3.9 0.26 11.2 0.2 2.1 2 1 0 2 2 2 0 PGC7/Stella/Dppa3 domain EGF PF00008.22 AEO55007.1 - 0.79 9.7 3.5 0.27 11.2 0.5 1.6 2 0 0 2 2 2 0 EGF-like domain F-box PF00646.28 AEO55008.1 - 0.00012 21.6 0.1 0.00024 20.6 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 AEO55008.1 - 0.00044 19.9 0.1 0.001 18.7 0.0 1.7 1 0 0 1 1 1 1 F-box-like MFS_1 PF07690.11 AEO55009.1 - 8.9e-12 44.3 27.2 8.9e-12 44.3 18.9 2.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF605 PF04652.11 AEO55009.1 - 4.1 6.7 10.2 6.8 5.9 7.1 1.3 1 0 0 1 1 1 0 Vta1 like His_Phos_1 PF00300.17 AEO55010.1 - 4.1e-09 36.7 0.1 2e-07 31.2 0.0 2.5 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Peptidase_C13 PF01650.13 AEO55011.1 - 1.3e-41 142.5 0.2 1.7e-41 142.2 0.1 1.1 1 0 0 1 1 1 1 Peptidase C13 family TFIIIC_delta PF12657.2 AEO55012.1 - 2.7e-17 63.0 0.0 1e-07 31.8 0.0 2.3 2 0 0 2 2 2 2 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.2 AEO55013.1 - 5.5e-10 39.0 0.1 8.9e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex ADK_lid PF05191.9 AEO55013.1 - 5.6 6.7 7.8 15 5.3 0.0 3.3 3 0 0 3 3 3 0 Adenylate kinase, active site lid Mito_carr PF00153.22 AEO55014.1 - 4.2e-59 196.2 7.5 2.2e-20 72.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Cation_efflux PF01545.16 AEO55015.1 - 8.6e-63 212.0 0.1 1.3e-62 211.4 0.0 1.2 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.17 AEO55015.1 - 8.8e-05 21.6 15.3 8.8e-05 21.6 10.6 3.2 2 1 0 2 2 2 1 ZIP Zinc transporter Glyco_trans_1_4 PF13692.1 AEO55016.1 - 8.1e-22 77.8 0.0 7.2e-21 74.7 0.0 2.4 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 AEO55016.1 - 0.011 15.9 0.0 0.027 14.7 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 UQ_con PF00179.21 AEO55017.1 - 1.4e-37 128.1 0.0 1.8e-37 127.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AEO55017.1 - 0.00068 19.4 0.1 0.0017 18.0 0.0 1.7 1 1 0 1 1 1 1 Prokaryotic E2 family B zf-C2H2_jaz PF12171.3 AEO55018.1 - 6.2e-07 29.3 0.3 1e-06 28.6 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding DUF1777 PF08648.7 AEO55018.1 - 6.2e-06 26.0 16.2 6.2e-06 26.0 11.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) zf-met PF12874.2 AEO55018.1 - 3.9e-05 23.6 0.4 6.7e-05 22.9 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type HemX PF04375.9 AEO55018.1 - 0.0093 14.6 1.3 0.013 14.0 0.9 1.2 1 0 0 1 1 1 1 HemX zf-DBF PF07535.7 AEO55018.1 - 0.031 13.9 0.1 0.067 12.8 0.0 1.5 1 0 0 1 1 1 0 DBF zinc finger AKAP95 PF04988.7 AEO55018.1 - 0.33 10.7 3.1 0.53 10.0 0.0 2.3 1 1 1 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) DUF1764 PF08576.5 AEO55018.1 - 1.4 9.7 10.0 2.2 9.1 3.7 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) CAF-1_p150 PF11600.3 AEO55018.1 - 5.2 6.3 34.4 0.32 10.3 15.1 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal MAT1 PF06391.8 AEO55018.1 - 5.7 6.4 18.9 1.6 8.2 8.4 2.2 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 TP_methylase PF00590.15 AEO55019.1 - 9.3e-20 71.2 0.0 1.7e-19 70.3 0.0 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Pyridox_oxidase PF01243.15 AEO55020.1 - 1.7e-08 34.3 0.0 2.7e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Glyco_hydro_92 PF07971.7 AEO55022.1 - 1.5e-168 561.5 0.0 1.9e-168 561.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 PAS_9 PF13426.1 AEO55023.1 - 1.3e-14 54.4 0.0 2.2e-12 47.2 0.0 3.1 3 0 0 3 3 3 1 PAS domain RGS PF00615.14 AEO55023.1 - 5.1e-05 23.3 0.0 0.00012 22.1 0.0 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain Lactamase_B_2 PF12706.2 AEO55024.1 - 2.3e-41 141.5 0.1 2.8e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 AEO55024.1 - 8e-12 45.1 0.0 2e-11 43.8 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 AEO55024.1 - 4.2e-07 29.8 0.8 2.5e-06 27.2 0.5 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Glyco_hydro_30 PF02055.11 AEO55025.1 - 2.7e-21 75.3 0.5 1.6e-14 52.9 0.2 2.4 2 1 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 AEO55025.1 - 3.6e-13 49.2 0.9 4.7e-12 45.5 0.0 2.4 2 0 0 2 2 2 1 O-Glycosyl hydrolase family 30 Polyketide_cyc2 PF10604.4 AEO55027.1 - 4.7e-07 30.0 0.6 5.7e-07 29.7 0.4 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport TAT_signal PF10518.4 AEO55027.1 - 0.029 14.3 0.3 0.053 13.5 0.2 1.5 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence Podoplanin PF05808.6 AEO55028.1 - 4.7e-08 32.7 1.8 7.6e-08 32.0 1.2 1.2 1 0 0 1 1 1 1 Podoplanin MGC-24 PF05283.6 AEO55028.1 - 0.00013 21.7 5.8 0.00031 20.5 4.0 1.6 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24) CFEM PF05730.6 AEO55028.1 - 0.00028 20.6 1.8 0.00059 19.6 1.2 1.5 1 0 0 1 1 1 1 CFEM domain TMEM154 PF15102.1 AEO55028.1 - 0.015 15.0 0.1 0.024 14.3 0.1 1.3 1 0 0 1 1 1 0 TMEM154 protein family Sporozoite_P67 PF05642.6 AEO55028.1 - 0.13 10.0 4.6 0.18 9.6 3.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ABC_tran PF00005.22 AEO55029.1 - 2e-41 141.4 0.0 2.7e-23 82.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 AEO55029.1 - 4.8e-32 111.4 21.1 1.5e-18 67.2 4.5 3.6 4 0 0 4 4 4 2 ABC transporter transmembrane region SMC_N PF02463.14 AEO55029.1 - 6.7e-11 41.8 2.0 4.6e-05 22.7 0.0 4.1 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 AEO55029.1 - 1.3e-08 35.1 0.1 0.053 13.4 0.0 4.2 4 0 0 4 4 4 2 AAA domain AAA_22 PF13401.1 AEO55029.1 - 1.6e-08 34.7 0.2 0.0012 19.0 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 AEO55029.1 - 3.4e-08 33.6 0.4 0.0011 18.9 0.1 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 AEO55029.1 - 3.4e-05 23.3 0.7 0.0073 15.7 0.1 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 AEO55029.1 - 8e-05 22.3 0.6 0.11 12.1 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_10 PF12846.2 AEO55029.1 - 8.8e-05 22.0 0.5 0.039 13.3 0.0 3.1 3 0 0 3 3 3 1 AAA-like domain Miro PF08477.8 AEO55029.1 - 0.0001 22.8 0.1 0.019 15.4 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein T2SE PF00437.15 AEO55029.1 - 0.00013 20.9 3.0 0.034 13.0 0.1 2.8 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_23 PF13476.1 AEO55029.1 - 0.00014 22.2 0.6 0.14 12.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 AEO55029.1 - 0.0003 19.9 0.1 0.15 11.2 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 AEO55029.1 - 0.00031 20.2 0.8 0.017 14.6 0.1 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_29 PF13555.1 AEO55029.1 - 0.001 18.5 6.3 0.0085 15.5 0.4 3.3 3 0 0 3 3 3 1 P-loop containing region of AAA domain NTPase_1 PF03266.10 AEO55029.1 - 0.0069 16.1 1.1 0.89 9.2 0.1 2.5 2 0 0 2 2 2 1 NTPase AAA_24 PF13479.1 AEO55029.1 - 0.011 15.2 2.6 0.081 12.4 0.1 2.5 3 0 0 3 3 2 0 AAA domain MobB PF03205.9 AEO55029.1 - 0.023 14.4 0.6 2.1 8.0 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 AEO55029.1 - 0.025 14.2 0.0 1.4 8.5 0.0 2.8 2 1 0 2 2 2 0 Archaeal ATPase SbcCD_C PF13558.1 AEO55029.1 - 0.047 13.5 0.0 8.1 6.4 0.0 2.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 AEO55029.1 - 0.05 14.4 0.3 0.23 12.2 0.0 2.4 2 0 0 2 2 1 0 AAA domain MMR_HSR1 PF01926.18 AEO55029.1 - 0.052 13.5 0.0 1.6 8.6 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.17 AEO55029.1 - 0.064 13.4 0.1 20 5.4 0.0 2.8 3 0 0 3 3 2 0 RNA helicase AAA_33 PF13671.1 AEO55029.1 - 0.068 13.0 0.0 7.7 6.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 AEO55029.1 - 0.07 12.9 0.8 0.16 11.7 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 Dynamin_N PF00350.18 AEO55029.1 - 0.074 12.8 0.2 5.4 6.8 0.1 2.4 2 0 0 2 2 2 0 Dynamin family ArgK PF03308.11 AEO55029.1 - 0.076 11.7 1.6 6.2 5.5 0.2 2.6 3 0 0 3 3 3 0 ArgK protein cobW PF02492.14 AEO55029.1 - 0.11 11.9 2.4 2.6 7.4 0.2 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.12 AEO55029.1 - 0.2 11.0 4.0 1.4 8.2 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein GTP_EFTU PF00009.22 AEO55029.1 - 0.21 10.9 0.5 7.6 5.9 0.2 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_18 PF13238.1 AEO55029.1 - 0.26 11.6 1.6 0.75 10.1 0.2 2.4 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 AEO55029.1 - 0.26 10.1 2.9 0.6 9.0 0.0 2.5 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) DEAD PF00270.24 AEO55029.1 - 0.31 10.5 0.8 6.1 6.3 0.2 2.6 3 0 0 3 3 2 0 DEAD/DEAH box helicase Zeta_toxin PF06414.7 AEO55029.1 - 0.43 9.6 1.4 20 4.2 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Pox_A32 PF04665.7 AEO55029.1 - 0.46 9.7 0.7 4.3 6.5 0.1 2.1 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_19 PF13245.1 AEO55029.1 - 0.54 10.0 5.7 1.6 8.5 0.6 2.9 2 0 0 2 2 2 0 Part of AAA domain Pkinase_Tyr PF07714.12 AEO55031.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.20 AEO55031.1 - 0.15 11.2 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Pkinase PF00069.20 AEO55032.1 - 3.2e-71 239.5 0.0 4.7e-71 238.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO55032.1 - 6.9e-34 117.0 0.0 9.5e-34 116.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 AEO55032.1 - 1e-09 38.7 1.2 3.2e-09 37.1 0.8 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 AEO55032.1 - 0.00079 18.4 0.0 0.0016 17.4 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 AEO55032.1 - 0.055 12.5 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PGI PF00342.14 AEO55033.1 - 2.5e-210 699.0 0.1 2.8e-210 698.8 0.1 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase CUE PF02845.11 AEO55034.1 - 4.2e-08 32.5 0.0 6.3e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 CUE domain Gly_transf_sug PF04488.10 AEO55037.1 - 9.7e-08 32.3 0.0 1.6e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 AEO55037.1 - 0.17 10.3 0.1 0.27 9.6 0.1 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain GMC_oxred_C PF05199.8 AEO55038.1 - 7.1e-06 26.3 1.1 1e-05 25.8 0.6 1.3 1 1 0 1 1 1 1 GMC oxidoreductase Cyt-b5 PF00173.23 AEO55039.1 - 9.1e-14 51.0 0.0 1.2e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MT0933_antitox PF14013.1 AEO55040.1 - 1.1 9.4 6.3 1.7 8.8 2.1 2.9 2 1 0 2 2 2 0 MT0933-like antitoxin protein Synaphin PF05835.7 AEO55040.1 - 4.8 7.3 8.3 0.92 9.6 2.8 1.8 1 1 1 2 2 2 0 Synaphin protein VPS9 PF02204.13 AEO55041.1 - 1.2e-30 105.5 0.1 2e-30 104.8 0.1 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 AEO55041.1 - 3.3e-05 23.2 0.1 0.00052 19.4 0.0 2.5 2 0 0 2 2 2 1 CUE domain CAP_N PF01213.14 AEO55041.1 - 0.074 12.3 0.2 0.074 12.3 0.1 4.6 3 2 1 5 5 5 0 Adenylate cyclase associated (CAP) N terminal Asn_synthase PF00733.16 AEO55042.1 - 1.4e-61 208.2 0.0 1.6e-61 208.0 0.0 1.0 1 0 0 1 1 1 1 Asparagine synthase NAD_synthase PF02540.12 AEO55042.1 - 0.074 11.9 0.0 0.18 10.7 0.0 1.6 2 0 0 2 2 2 0 NAD synthase DUF4013 PF13197.1 AEO55043.1 - 0.1 11.8 5.4 0.35 10.1 3.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4013) DUF2217 PF10265.4 AEO55044.1 - 0.00023 20.0 0.7 0.00029 19.7 0.5 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2217) DUF1191 PF06697.7 AEO55044.1 - 0.043 12.6 0.6 0.06 12.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1191) AP2 PF00847.15 AEO55044.1 - 0.26 11.4 1.6 0.28 11.3 0.1 1.9 2 0 0 2 2 2 0 AP2 domain TFIIB PF00382.14 AEO55045.1 - 5.2e-36 122.2 1.1 2.8e-19 68.6 0.2 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 AEO55045.1 - 6.9e-13 47.6 1.1 1.1e-12 47.0 0.7 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.14 AEO55045.1 - 0.00051 19.9 0.0 0.69 9.8 0.0 2.4 1 1 1 2 2 2 2 Cyclin, C-terminal domain zf-ribbon_3 PF13248.1 AEO55045.1 - 0.074 12.2 0.4 0.19 10.9 0.3 1.7 1 0 0 1 1 1 0 zinc-ribbon domain Cyclin_N PF00134.18 AEO55045.1 - 0.095 12.2 0.1 1.9 8.0 0.0 2.2 2 0 0 2 2 2 0 Cyclin, N-terminal domain PhnA_Zn_Ribbon PF08274.7 AEO55045.1 - 0.1 12.4 1.3 0.77 9.5 0.1 2.3 2 0 0 2 2 2 0 PhnA Zinc-Ribbon CRC_subunit PF08624.5 AEO55046.1 - 4.8e-59 198.2 0.0 7.1e-59 197.6 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit CDC45 PF02724.9 AEO55046.1 - 0.61 8.0 6.0 0.87 7.5 4.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2890 PF11081.3 AEO55046.1 - 5.5 6.9 10.0 11 6.0 6.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Nop14 PF04147.7 AEO55046.1 - 6.1 4.6 16.8 11 3.7 11.7 1.3 1 0 0 1 1 1 0 Nop14-like family Cyclin PF08613.6 AEO55047.1 - 2.6e-13 50.6 0.0 3.8e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Cyclin DUF221 PF02714.10 AEO55047.1 - 0.0045 15.9 0.0 0.0064 15.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF221 Nefa_Nip30_N PF10187.4 AEO55048.1 - 1e-23 83.4 15.2 2.3e-23 82.2 10.5 1.7 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 Serglycin PF04360.7 AEO55048.1 - 0.11 12.2 0.1 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 Serglycin IncA PF04156.9 AEO55048.1 - 0.26 10.8 11.0 0.39 10.2 7.6 1.2 1 0 0 1 1 1 0 IncA protein DOR PF14839.1 AEO55048.1 - 0.89 9.2 17.3 0.088 12.5 7.6 2.2 3 0 0 3 3 3 0 DOR family SOBP PF15279.1 AEO55048.1 - 4.6 7.5 6.5 1.2 9.3 2.2 1.6 2 0 0 2 2 2 0 Sine oculis-binding protein DUF2058 PF09831.4 AEO55048.1 - 7.3 6.4 13.2 0.28 11.0 5.1 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) Tim54 PF11711.3 AEO55049.1 - 2.3e-132 441.2 0.3 2.8e-132 440.9 0.2 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Pkinase PF00069.20 AEO55050.1 - 3.1e-56 190.4 0.2 8.7e-40 136.5 0.2 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AEO55050.1 - 9.5e-27 93.6 0.2 6.6e-21 74.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 AEO55050.1 - 0.00011 21.3 0.0 0.00021 20.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AEO55050.1 - 0.00018 21.3 0.1 0.019 14.6 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 AEO55050.1 - 0.00061 18.9 0.0 0.0013 17.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family BUD22 PF09073.5 AEO55050.1 - 0.007 15.4 2.9 0.011 14.8 2.0 1.2 1 0 0 1 1 1 1 BUD22 Pkinase_C PF00433.19 AEO55050.1 - 0.031 14.8 0.6 0.079 13.4 0.4 1.8 1 0 0 1 1 1 0 Protein kinase C terminal domain Pox_ser-thr_kin PF05445.6 AEO55050.1 - 0.04 12.7 0.1 0.062 12.0 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.6 AEO55050.1 - 0.063 12.1 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.17 AEO55050.1 - 0.13 11.6 3.2 0.31 10.3 0.0 2.2 2 0 0 2 2 2 0 RIO1 family zf-met PF12874.2 AEO55051.1 - 6.9e-06 26.0 1.3 1.5e-05 25.0 0.7 1.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.4 AEO55051.1 - 0.00019 21.0 0.1 0.00027 20.5 0.0 1.2 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein PRP4 PF08799.6 AEO55051.1 - 0.056 12.7 0.9 0.098 11.9 0.6 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like CoA_transf_3 PF02515.12 AEO55052.1 - 1.1e-58 197.6 0.0 2.1e-58 196.7 0.0 1.4 1 0 0 1 1 1 1 CoA-transferase family III PHD PF00628.24 AEO55053.1 - 2.1e-07 30.5 9.6 3.8e-07 29.6 6.7 1.4 1 0 0 1 1 1 1 PHD-finger Cut8_M PF14483.1 AEO55053.1 - 0.0091 15.7 0.6 0.019 14.7 0.4 1.4 1 0 0 1 1 1 1 Cut8 dimerisation domain Mucin PF01456.12 AEO55053.1 - 0.012 15.3 11.6 0.012 15.3 8.0 4.8 2 1 1 3 3 3 0 Mucin-like glycoprotein FYVE_2 PF02318.11 AEO55053.1 - 0.042 13.7 4.4 0.07 13.0 3.1 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger SelP_N PF04592.9 AEO55053.1 - 0.56 9.5 14.8 1.5 8.1 10.3 1.7 1 0 0 1 1 1 0 Selenoprotein P, N terminal region PHD_2 PF13831.1 AEO55053.1 - 5.9 6.2 10.3 1.3 8.3 3.5 2.5 2 1 0 2 2 2 0 PHD-finger PBP1_TM PF14812.1 AEO55053.1 - 9.4 6.6 8.7 3.5 7.9 1.2 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal WD40 PF00400.27 AEO55054.1 - 1.6e-06 27.7 2.4 7.9e-06 25.5 0.1 3.3 3 1 0 3 3 3 1 WD domain, G-beta repeat NACHT PF05729.7 AEO55054.1 - 3.3e-05 23.5 0.0 7.2e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 AEO55054.1 - 0.0013 18.7 0.1 0.006 16.5 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 AEO55054.1 - 0.21 10.4 0.0 0.49 9.1 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain 3HCDH_N PF02737.13 AEO55055.1 - 1.9e-28 99.3 0.0 5.4e-28 97.8 0.0 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 AEO55055.1 - 3.1e-13 49.9 0.0 5.3e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Pyr_redox PF00070.22 AEO55055.1 - 0.00079 19.7 0.0 0.0018 18.6 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 AEO55055.1 - 0.0008 18.6 0.0 0.0013 17.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 AEO55055.1 - 0.0033 17.4 0.0 0.0062 16.5 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain NAD_Gly3P_dh_N PF01210.18 AEO55055.1 - 0.0042 16.8 0.0 0.0075 16.0 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 AEO55055.1 - 0.12 12.2 0.0 0.36 10.6 0.0 1.8 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.1 AEO55055.1 - 0.15 12.3 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF2207 PF09972.4 AEO55057.1 - 0.0015 17.2 0.0 0.0018 16.9 0.0 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF1517 PF07466.6 AEO55057.1 - 0.0031 16.5 0.6 0.0031 16.5 0.4 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1517) DUF3329 PF11808.3 AEO55057.1 - 0.069 13.2 0.1 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3329) CcmD PF04995.9 AEO55057.1 - 0.1 12.3 0.2 0.17 11.6 0.1 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF202 PF02656.10 AEO55057.1 - 0.14 12.4 0.2 0.22 11.7 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF202) DUF566 PF04484.7 AEO55057.1 - 0.57 9.6 8.2 0.7 9.3 5.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Glyco_transf_25 PF01755.12 AEO55058.1 - 6.6e-13 48.7 0.0 5.4e-09 35.9 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) TIM PF00121.13 AEO55059.1 - 1.5e-50 171.5 0.0 1.8e-50 171.2 0.0 1.1 1 0 0 1 1 1 1 Triosephosphate isomerase LacAB_rpiB PF02502.13 AEO55060.1 - 3.2e-42 143.5 0.8 3.6e-42 143.3 0.6 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase DUF3773 PF12608.3 AEO55060.1 - 0.0024 17.8 0.1 0.0059 16.6 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3773) Dak1 PF02733.12 AEO55061.1 - 1.6e-110 368.7 0.0 2.2e-110 368.2 0.0 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 AEO55061.1 - 2e-39 135.0 4.7 3.8e-39 134.1 3.2 1.5 1 0 0 1 1 1 1 DAK2 domain DUF2497 PF10691.4 AEO55061.1 - 0.12 12.3 0.0 19 5.2 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2497) F_bP_aldolase PF01116.15 AEO55062.1 - 1.3e-85 286.9 0.1 1.5e-85 286.8 0.1 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II PTE PF02126.13 AEO55062.1 - 0.047 12.7 0.0 0.08 11.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotriesterase family NAD_binding_11 PF14833.1 AEO55063.1 - 1.8e-37 128.0 1.4 5e-26 91.1 0.1 2.4 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 AEO55063.1 - 3.4e-33 114.7 0.0 7.3e-33 113.7 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase SET PF00856.23 AEO55063.1 - 3.9e-20 72.7 0.1 3.1e-19 69.8 0.0 2.5 2 1 0 2 2 2 1 SET domain Pre-SET PF05033.11 AEO55063.1 - 5.8e-20 71.4 3.4 5.8e-20 71.4 2.3 2.2 2 0 0 2 2 2 1 Pre-SET motif F420_oxidored PF03807.12 AEO55063.1 - 0.00024 21.4 0.0 0.00075 19.8 0.0 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 AEO55063.1 - 0.00082 19.0 0.2 0.0021 17.7 0.0 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 AEO55063.1 - 0.0084 15.5 0.1 0.02 14.3 0.0 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Gly_transf_sug PF04488.10 AEO55065.1 - 1.3e-11 44.8 0.0 2.4e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 AEO55065.1 - 0.0015 17.7 0.0 0.0023 17.1 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.2 AEO55065.1 - 0.024 13.1 0.0 0.034 12.6 0.0 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Adaptin_N PF01602.15 AEO55066.1 - 9.3e-92 308.0 6.0 1.6e-91 307.2 4.2 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.7 AEO55066.1 - 1.6e-62 209.2 0.8 3.4e-62 208.2 0.6 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.1 AEO55066.1 - 2.2e-62 208.5 0.0 6.4e-62 207.0 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform HEAT_2 PF13646.1 AEO55066.1 - 1.1e-09 38.4 9.3 0.0002 21.5 0.0 5.0 2 1 2 4 4 4 3 HEAT repeats Cnd1 PF12717.2 AEO55066.1 - 0.001 18.9 10.7 0.01 15.6 0.0 4.2 2 2 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 AEO55066.1 - 0.0036 17.2 0.5 1.8 8.8 0.0 4.2 4 0 0 4 4 4 1 HEAT repeat RE_Alw26IDE PF09665.5 AEO55066.1 - 5 5.7 11.4 0.32 9.6 1.1 3.1 3 1 1 4 4 4 0 Type II restriction endonuclease (RE_Alw26IDE) Mago_nashi PF02792.9 AEO55067.1 - 2.7e-76 254.1 0.4 3.1e-76 253.8 0.2 1.0 1 0 0 1 1 1 1 Mago nashi protein FlbT PF07378.6 AEO55067.1 - 0.062 13.1 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Flagellar protein FlbT Vac_ImportDeg PF09783.4 AEO55068.1 - 7.4e-70 234.0 2.5 1e-69 233.5 1.8 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein Vesiculo_matrix PF06326.7 AEO55068.1 - 0.15 11.4 2.1 0.27 10.6 1.4 1.3 1 0 0 1 1 1 0 Vesiculovirus matrix protein UPF0020 PF01170.13 AEO55069.1 - 6.2e-10 38.9 0.2 4.6e-09 36.0 0.1 2.0 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 AEO55069.1 - 1.7e-07 31.2 0.0 3.7e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain TylF PF05711.6 AEO55069.1 - 0.088 11.8 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) Ribonuc_P_40 PF08584.6 AEO55070.1 - 4.6e-72 242.4 0.0 6.4e-72 241.9 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit EF_assoc_1 PF08355.7 AEO55070.1 - 0.001 18.2 0.0 0.0022 17.2 0.0 1.5 1 0 0 1 1 1 1 EF hand associated Ank_5 PF13857.1 AEO55071.1 - 2.3e-11 43.5 0.0 4e-08 33.2 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 AEO55071.1 - 5.6e-09 36.2 0.9 1.5e-05 25.3 0.0 2.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 AEO55071.1 - 0.00073 19.5 0.1 0.0073 16.4 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 AEO55071.1 - 0.00086 19.5 0.1 0.0023 18.2 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 AEO55071.1 - 0.011 15.5 0.0 0.058 13.2 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeat tRNA_lig_CPD PF08302.6 AEO55072.1 - 7.4e-83 277.7 0.0 1e-82 277.2 0.0 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain RNA_lig_T4_1 PF09511.5 AEO55072.1 - 1.6e-81 273.0 0.0 4.7e-81 271.4 0.0 1.8 2 0 0 2 2 2 1 RNA ligase tRNA_lig_kinase PF08303.6 AEO55072.1 - 1.3e-57 194.3 0.0 3e-57 193.1 0.0 1.7 1 0 0 1 1 1 1 tRNA ligase kinase domain Glycos_transf_3 PF00591.16 AEO55073.1 - 1.7e-63 214.3 0.0 1.1e-62 211.7 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 AEO55073.1 - 6.9e-10 38.3 0.0 2.3e-09 36.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain Ribosomal_L10 PF00466.15 AEO55074.1 - 0.00038 20.3 0.0 0.0059 16.5 0.0 2.6 1 1 0 1 1 1 1 Ribosomal protein L10 Tic20 PF09685.5 AEO55075.1 - 9.1e-08 32.0 1.3 1.2e-07 31.6 0.9 1.1 1 0 0 1 1 1 1 Tic20-like protein DUF3782 PF12644.2 AEO55075.1 - 0.081 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) AAA PF00004.24 AEO55076.1 - 1.8e-40 138.1 0.0 4.7e-40 136.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 AEO55076.1 - 8.3e-05 22.3 0.1 0.00048 19.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 AEO55076.1 - 0.00022 21.2 0.4 0.014 15.3 0.0 2.8 2 1 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 AEO55076.1 - 0.00026 20.1 0.0 0.00067 18.7 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 AEO55076.1 - 0.00095 19.1 0.0 0.0076 16.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 AEO55076.1 - 0.0031 17.6 3.6 0.019 15.1 0.0 2.9 3 1 1 4 4 3 1 AAA domain PhoH PF02562.11 AEO55076.1 - 0.0038 16.4 0.4 0.048 12.8 0.1 2.2 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.16 AEO55076.1 - 0.0073 15.4 0.0 0.02 14.0 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 AEO55076.1 - 0.0087 15.9 0.0 0.025 14.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AEO55076.1 - 0.018 14.8 0.4 0.044 13.5 0.3 1.6 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 AEO55076.1 - 0.023 14.1 0.1 0.047 13.0 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF815 PF05673.8 AEO55076.1 - 0.03 13.2 0.0 0.066 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.1 AEO55076.1 - 0.036 13.4 1.6 0.33 10.3 0.2 2.5 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 AEO55076.1 - 0.05 13.1 0.1 0.14 11.7 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 AEO55076.1 - 0.09 13.6 0.2 0.09 13.6 0.1 2.8 2 2 0 2 2 2 0 AAA domain AAA_11 PF13086.1 AEO55076.1 - 0.11 12.0 0.7 0.52 9.8 0.0 2.3 2 2 0 2 2 2 0 AAA domain Clr5 PF14420.1 AEO55077.1 - 1.2e-22 79.5 2.1 1.9e-22 78.9 1.5 1.3 1 0 0 1 1 1 1 Clr5 domain Ish1 PF10281.4 AEO55078.1 - 3.3e-76 250.8 18.5 9.3e-13 47.9 0.0 9.9 10 0 0 10 10 10 8 Putative stress-responsive nuclear envelope protein SAP PF02037.22 AEO55078.1 - 8.3e-10 37.9 0.0 0.11 12.0 0.0 6.8 8 0 0 8 8 8 2 SAP domain Slx4 PF09494.5 AEO55078.1 - 4.8e-07 29.4 9.2 0.64 9.8 0.0 7.0 8 0 0 8 8 8 2 Slx4 endonuclease HeH PF12949.2 AEO55078.1 - 1.2e-06 27.9 0.0 6.3 6.4 0.0 6.3 6 0 0 6 6 6 1 HeH/LEM domain APC2 PF08672.6 AEO55078.1 - 0.0026 17.9 2.5 51 4.2 0.0 6.1 8 0 0 8 8 8 0 Anaphase promoting complex (APC) subunit 2 Phasin PF05597.6 AEO55078.1 - 0.048 13.4 7.8 6.1 6.6 0.0 4.6 4 1 1 5 5 5 0 Poly(hydroxyalcanoate) granule associated protein (phasin) SAM_2 PF07647.12 AEO55078.1 - 0.19 11.5 0.7 2.4 8.0 0.1 3.3 5 0 0 5 5 5 0 SAM domain (Sterile alpha motif) TrbL PF04610.9 AEO55078.1 - 3.6 7.2 5.3 20 4.7 1.3 2.4 1 1 1 2 2 2 0 TrbL/VirB6 plasmid conjugal transfer protein DUF3714 PF12508.3 AEO55078.1 - 9.7 5.5 6.6 21 4.5 1.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3714) MFS_1 PF07690.11 AEO55081.1 - 4.1e-47 160.6 46.5 7.6e-46 156.4 32.2 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Dispanin PF04505.7 AEO55081.1 - 0.022 14.3 0.1 0.33 10.5 0.0 3.2 2 0 0 2 2 2 0 Interferon-induced transmembrane protein Glyco_hydro_61 PF03443.9 AEO55082.1 - 1.8e-40 139.0 0.0 2.2e-40 138.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 KAR9 PF08580.5 AEO55083.1 - 0.26 9.5 5.2 0.29 9.3 3.6 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Annexin PF00191.15 AEO55084.1 - 7.1e-58 192.4 3.2 1.9e-17 62.9 0.2 4.3 4 0 0 4 4 4 4 Annexin Acetyltransf_11 PF13720.1 AEO55084.1 - 0.0038 17.4 2.5 2.4 8.4 0.0 3.5 3 0 0 3 3 3 2 Udp N-acetylglucosamine O-acyltransferase; Domain 2 zf-RING_3 PF14369.1 AEO55085.1 - 0.54 10.2 3.2 1 9.4 0.7 2.3 2 0 0 2 2 2 0 zinc-finger zf-C2HC_2 PF13913.1 AEO55085.1 - 0.64 9.7 7.2 2.1 8.1 0.6 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zinc_ribbon_5 PF13719.1 AEO55085.1 - 1.2 8.7 2.7 5.4 6.6 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2 PF00096.21 AEO55085.1 - 2.4 8.6 14.6 2.8 8.4 1.9 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type HR1 PF02185.11 AEO55086.1 - 0.52 10.0 4.9 0.96 9.2 2.9 1.8 1 1 1 2 2 2 0 Hr1 repeat DUF3786 PF12654.2 AEO55087.1 - 0.021 14.1 0.2 0.027 13.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3786) RVT_1 PF00078.22 AEO55087.1 - 0.05 12.9 0.4 0.052 12.8 0.3 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Herpes_U15 PF05613.6 AEO55087.1 - 1.1 9.6 4.2 2.5 8.4 2.9 1.7 1 1 0 1 1 1 0 Human herpesvirus U15 protein Git3 PF11710.3 AEO55088.1 - 6.8e-15 55.1 11.6 2e-14 53.6 8.1 1.7 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 AEO55088.1 - 5.9e-13 48.5 0.0 8.6e-13 48.0 0.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.6 AEO55088.1 - 0.00077 18.4 7.5 0.0012 17.8 5.2 1.1 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.19 AEO55088.1 - 0.014 14.5 4.8 0.02 13.9 3.3 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) RCR PF12273.3 AEO55088.1 - 0.085 13.4 0.5 0.23 11.9 0.0 1.9 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red CDO_I PF05995.7 AEO55089.1 - 7.7e-41 139.1 0.0 9e-41 138.9 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 AEO55089.1 - 0.0036 16.6 0.4 0.007 15.7 0.3 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1637) Voltage_CLC PF00654.15 AEO55091.1 - 3.9e-90 302.4 28.3 4.8e-90 302.1 19.6 1.1 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.23 AEO55091.1 - 1.2e-12 47.3 0.1 5.4e-05 22.8 0.0 2.5 2 0 0 2 2 2 2 CBS domain CBFD_NFYB_HMF PF00808.18 AEO55092.1 - 4.4e-10 39.4 0.1 7.9e-10 38.6 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone LRR_9 PF14580.1 AEO55093.1 - 3.6e-47 160.1 0.5 4.9e-47 159.7 0.0 1.5 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.2 AEO55093.1 - 7.6e-11 41.3 18.5 6.4e-06 25.6 2.9 3.9 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AEO55093.1 - 4.3e-09 35.9 1.1 4.3e-09 35.9 0.8 3.1 4 0 0 4 4 4 1 Leucine rich repeat LRR_7 PF13504.1 AEO55093.1 - 0.00025 20.7 8.3 2.1 8.8 0.0 4.9 5 0 0 5 5 5 2 Leucine rich repeat LRR_1 PF00560.28 AEO55093.1 - 0.016 15.1 11.3 2.3 8.5 0.0 5.4 5 1 0 5 5 5 0 Leucine Rich Repeat DUF4349 PF14257.1 AEO55093.1 - 0.017 14.3 2.5 0.026 13.7 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) LRR_6 PF13516.1 AEO55093.1 - 0.059 13.4 5.4 16 5.9 0.0 4.5 5 0 0 5 5 5 0 Leucine Rich repeat PspB PF06667.7 AEO55093.1 - 0.2 11.6 1.8 0.38 10.7 0.6 1.9 2 0 0 2 2 2 0 Phage shock protein B Pkinase PF00069.20 AEO55094.1 - 2.2e-27 95.8 0.0 3.3e-27 95.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 AEO55094.1 - 7.9e-17 60.4 3.4 8.6e-09 34.9 0.1 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat HEAT PF02985.17 AEO55094.1 - 1.4e-08 34.0 0.3 0.2 11.8 0.0 6.3 6 0 0 6 6 6 2 HEAT repeat Pkinase_Tyr PF07714.12 AEO55094.1 - 1.4e-07 30.9 0.0 2e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.1 AEO55094.1 - 0.0012 19.1 0.8 0.61 10.3 0.0 3.9 1 1 3 4 4 4 2 HEAT repeats RasGEF_N_2 PF14663.1 AEO55094.1 - 0.065 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Kinase-like PF14531.1 AEO55094.1 - 0.13 11.1 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like SH3_9 PF14604.1 AEO55095.1 - 7.6e-07 28.6 0.2 1.8e-06 27.4 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 AEO55095.1 - 8e-05 21.9 0.4 0.00017 20.9 0.3 1.6 1 0 0 1 1 1 1 SH3 domain Adeno_E3_CR2 PF02439.10 AEO55095.1 - 0.039 13.4 0.1 0.087 12.3 0.0 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF3112 PF11309.3 AEO55096.1 - 2.9e-36 124.6 18.6 1.6e-33 115.7 1.3 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF3112) Metallophos PF00149.23 AEO55097.1 - 3e-44 150.8 1.0 3.8e-44 150.4 0.7 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Vps51 PF08700.6 AEO55098.1 - 6.7e-18 64.3 4.2 6.7e-18 64.3 2.9 2.7 3 0 0 3 3 3 1 Vps51/Vps67 COG2 PF06148.6 AEO55098.1 - 1.2e-05 25.2 2.4 0.0013 18.6 0.1 2.5 2 0 0 2 2 2 2 COG (conserved oligomeric Golgi) complex component, COG2 Laminin_B PF00052.13 AEO55098.1 - 0.0042 16.6 0.6 0.036 13.6 0.4 2.4 1 1 0 1 1 1 1 Laminin B (Domain IV) HrcA_DNA-bdg PF03444.10 AEO55098.1 - 0.071 12.5 0.5 0.2 11.1 0.4 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding Sec5 PF15469.1 AEO55098.1 - 0.14 11.8 7.5 0.23 11.1 0.6 2.7 3 0 0 3 3 3 0 Exocyst complex component Sec5 V_ATPase_I PF01496.14 AEO55098.1 - 0.39 8.5 11.7 0.064 11.1 0.7 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF2383 PF09537.5 AEO55098.1 - 0.46 10.7 4.9 1.4 9.1 0.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) Atg14 PF10186.4 AEO55098.1 - 0.71 8.7 15.2 0.017 14.1 1.3 2.6 3 0 0 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 Baculo_PEP_C PF04513.7 AEO55098.1 - 1.4 8.7 6.2 0.38 10.5 0.4 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF342 PF03961.8 AEO55098.1 - 2.2 6.6 10.5 0.25 9.6 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF342) Herpes_UL32 PF06070.6 AEO55099.1 - 1.1 7.5 9.6 1.2 7.4 6.7 1.0 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Mucin PF01456.12 AEO55100.1 - 0.0013 18.5 11.3 0.0013 18.5 7.8 2.0 2 0 0 2 2 2 1 Mucin-like glycoprotein DUF566 PF04484.7 AEO55100.1 - 1.3 8.4 10.2 1.7 8.0 7.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) MGC-24 PF05283.6 AEO55100.1 - 2.1 8.0 15.6 0.44 10.3 6.7 2.2 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) MSA-2c PF12238.3 AEO55100.1 - 6 6.4 7.8 9.1 5.8 5.4 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c Methyltransf_2 PF00891.13 AEO55101.1 - 5.6e-28 97.7 0.0 1.4e-27 96.4 0.0 1.6 1 1 0 1 1 1 1 O-methyltransferase MAS20 PF02064.10 AEO55102.1 - 1.8e-13 50.4 1.6 3.9e-13 49.3 1.1 1.5 1 1 0 1 1 1 1 MAS20 protein import receptor SpaB_C PF14028.1 AEO55102.1 - 0.31 10.5 7.4 0.16 11.4 4.1 1.3 2 0 0 2 2 2 0 SpaB C-terminal domain GEMIN8 PF15348.1 AEO55102.1 - 1.2 9.1 6.2 1.7 8.6 4.3 1.1 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Wyosine_form PF08608.7 AEO55103.1 - 7.5e-25 86.8 0.0 2.2e-24 85.3 0.0 1.9 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.16 AEO55103.1 - 1.4e-22 80.6 0.1 2.9e-22 79.6 0.1 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.20 AEO55103.1 - 2.1e-09 37.5 0.2 3.4e-07 30.3 0.1 3.1 1 1 0 1 1 1 1 Flavodoxin Kinase-like PF14531.1 AEO55103.1 - 0.082 11.8 0.0 0.17 10.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like EmrE PF13536.1 AEO55104.1 - 2.3e-05 24.5 2.7 2.3e-05 24.5 1.9 1.6 2 0 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 AEO55104.1 - 0.002 18.1 12.4 0.0081 16.2 7.7 2.0 1 1 1 2 2 2 1 EamA-like transporter family UPF0546 PF10639.4 AEO55104.1 - 0.004 16.9 2.2 0.0051 16.6 1.5 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0546 TPT PF03151.11 AEO55104.1 - 1.4 8.5 9.5 1.7 8.3 4.2 2.0 1 1 1 2 2 2 0 Triose-phosphate Transporter family TFIIA_gamma_C PF02751.9 AEO55105.1 - 3.4e-26 90.8 1.3 4.6e-26 90.3 0.9 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 AEO55105.1 - 1.8e-25 88.2 0.2 2.5e-25 87.7 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain ATP-synt_C PF00137.16 AEO55106.1 - 7.5e-29 99.4 32.6 2e-17 62.8 5.2 3.2 3 1 0 3 3 3 2 ATP synthase subunit C Oxidored_q2 PF00420.19 AEO55106.1 - 0.36 10.4 5.8 0.58 9.7 1.8 2.7 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Cation_efflux PF01545.16 AEO55106.1 - 1 8.3 11.6 0.046 12.7 1.9 2.3 1 1 1 2 2 2 0 Cation efflux family MoCF_biosynth PF00994.19 AEO55107.1 - 9.8e-55 183.9 1.4 4e-31 107.3 0.0 2.2 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 AEO55107.1 - 3.3e-27 94.8 10.9 2.5e-19 69.2 2.4 2.9 2 1 0 2 2 2 2 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 AEO55107.1 - 4.9e-16 58.4 0.5 1.4e-15 57.0 0.0 2.1 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) DUF1206 PF06724.6 AEO55107.1 - 2.4 7.9 5.4 2.5 7.9 0.5 3.0 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1206) RNase_P_Rpp14 PF01900.14 AEO55108.1 - 8.1e-36 122.1 0.0 1.1e-35 121.7 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family ATP_bind_1 PF03029.12 AEO55109.1 - 1.4e-65 221.1 0.0 2.4e-65 220.4 0.0 1.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein WD40 PF00400.27 AEO55110.1 - 4.6e-20 70.6 2.0 4.5e-06 26.3 0.2 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat WD40 PF00400.27 AEO55112.1 - 7e-40 133.5 5.8 6e-10 38.6 0.2 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 AEO55112.1 - 1.1e-06 27.1 10.0 0.024 12.8 0.3 4.7 2 2 3 5 5 5 3 Nucleoporin Nup120/160 IncA PF04156.9 AEO55112.1 - 0.033 13.7 1.2 0.052 13.1 0.8 1.2 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 AEO55112.1 - 0.044 12.8 0.6 0.069 12.1 0.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 PQQ_2 PF13360.1 AEO55112.1 - 0.064 12.7 1.2 0.81 9.0 0.0 2.7 2 1 0 3 3 3 0 PQQ-like domain BCIP PF13862.1 AEO55113.1 - 5.7e-65 218.4 0.3 7.3e-65 218.1 0.2 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein COPI_assoc PF08507.5 AEO55114.1 - 7.4e-46 155.2 6.8 8.1e-46 155.1 4.7 1.0 1 0 0 1 1 1 1 COPI associated protein ExoD PF06055.7 AEO55114.1 - 0.0056 15.8 5.1 0.019 14.0 0.9 2.1 2 0 0 2 2 2 1 Exopolysaccharide synthesis, ExoD UCR_Fe-S_N PF10399.4 AEO55114.1 - 0.087 12.0 0.1 0.17 11.0 0.1 1.4 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal LrgA PF03788.9 AEO55114.1 - 0.15 11.8 2.5 0.71 9.6 1.6 2.0 1 1 0 1 1 1 0 LrgA family DUF308 PF03729.8 AEO55114.1 - 10 6.2 20.3 1.4 9.0 4.4 2.8 2 1 1 3 3 3 0 Short repeat of unknown function (DUF308) GATA PF00320.22 AEO55115.1 - 1.8e-32 110.3 14.2 6.7e-17 60.5 2.1 2.5 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 AEO55115.1 - 1.6e-07 30.4 3.4 0.00046 19.4 0.1 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.5 AEO55115.1 - 5.8e-05 22.9 1.4 0.27 11.2 0.1 2.7 2 0 0 2 2 2 2 Zinc ribbon domain RRN7 PF11781.3 AEO55115.1 - 0.0038 16.6 7.5 0.021 14.3 0.4 2.7 2 1 0 2 2 2 1 RNA polymerase I-specific transcription initiation factor Rrn7 zf-ribbon_3 PF13248.1 AEO55115.1 - 0.016 14.3 9.6 0.27 10.4 0.2 3.2 2 1 0 2 2 2 0 zinc-ribbon domain DZR PF12773.2 AEO55115.1 - 0.026 14.3 14.3 4.4 7.2 3.8 3.2 1 1 1 2 2 2 0 Double zinc ribbon ArfGap PF01412.13 AEO55115.1 - 0.032 13.9 3.1 2.7 7.8 0.1 2.4 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf FYVE PF01363.16 AEO55115.1 - 0.034 14.0 1.2 2.8 7.8 0.0 2.7 2 0 0 2 2 2 0 FYVE zinc finger Auto_anti-p27 PF06677.7 AEO55115.1 - 0.084 12.6 3.9 1.9 8.3 0.2 2.5 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) OrfB_Zn_ribbon PF07282.6 AEO55115.1 - 0.15 11.7 10.7 0.12 12.0 0.2 2.8 3 0 0 3 3 3 0 Putative transposase DNA-binding domain ADK_lid PF05191.9 AEO55115.1 - 0.17 11.5 6.5 0.59 9.8 0.2 3.4 3 0 0 3 3 3 0 Adenylate kinase, active site lid Zn_Tnp_IS1595 PF12760.2 AEO55115.1 - 0.27 11.0 5.5 1.1 9.1 0.4 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain HypA PF01155.14 AEO55115.1 - 1.1 8.9 6.8 2.2 7.9 0.1 2.7 3 0 0 3 3 3 0 Hydrogenase expression/synthesis hypA family zf-Sec23_Sec24 PF04810.10 AEO55115.1 - 5 6.7 15.3 0.12 11.9 0.3 3.3 4 0 0 4 4 4 0 Sec23/Sec24 zinc finger eIF-5_eIF-2B PF01873.12 AEO55115.1 - 6 6.5 7.1 3.5 7.2 0.2 2.7 3 0 0 3 3 3 0 Domain found in IF2B/IF5 SAP PF02037.22 AEO55117.1 - 2.4e-12 46.0 0.4 4.1e-12 45.2 0.3 1.4 1 0 0 1 1 1 1 SAP domain RRM_5 PF13893.1 AEO55117.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO55117.1 - 0.19 11.7 0.0 0.51 10.3 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CPSase_sm_chain PF00988.17 AEO55118.1 - 1e-46 157.6 0.0 1.6e-46 157.0 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 AEO55118.1 - 8.5e-45 152.5 0.0 1.3e-44 151.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 AEO55118.1 - 8.3e-07 28.6 0.2 0.00013 21.5 0.2 2.7 1 1 0 1 1 1 1 Peptidase C26 ETF PF01012.16 AEO55119.1 - 5.7e-38 130.2 0.5 7.5e-38 129.8 0.4 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ArfGap PF01412.13 AEO55120.1 - 1.1e-31 108.9 0.1 1.9e-31 108.2 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf RRM_1 PF00076.17 AEO55121.1 - 1.9e-31 107.4 0.1 5.1e-15 54.8 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO55121.1 - 5.2e-25 87.2 0.0 1.9e-12 46.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO55121.1 - 8.3e-09 35.1 0.0 0.0014 18.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) API5 PF05918.6 AEO55121.1 - 0.0016 17.0 2.5 0.0025 16.3 1.7 1.2 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) DbpA PF03880.10 AEO55121.1 - 0.048 13.3 0.1 9.2 6.0 0.0 2.9 3 0 0 3 3 3 0 DbpA RNA binding domain FAD_binding_1 PF00667.15 AEO55122.1 - 5.2e-28 97.9 0.0 8.5e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 AEO55122.1 - 5.6e-27 94.5 0.0 8.8e-27 93.8 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 AEO55122.1 - 5.5e-09 36.5 0.0 2.5e-06 27.9 0.0 2.5 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain Flavodoxin_3 PF12641.2 AEO55122.1 - 0.0015 17.9 0.0 0.0027 17.1 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_5 PF12724.2 AEO55122.1 - 0.045 13.7 0.0 0.14 12.1 0.0 1.8 2 0 0 2 2 2 0 Flavodoxin domain Asp PF00026.18 AEO55123.1 - 2.2e-10 40.3 0.1 5.4e-10 39.0 0.1 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease AJAP1_PANP_C PF15298.1 AEO55123.1 - 0.00013 21.9 0.0 0.00037 20.4 0.0 1.7 1 0 0 1 1 1 1 AJAP1/PANP C-terminus TMEM51 PF15345.1 AEO55123.1 - 0.0095 15.6 0.0 0.025 14.3 0.0 1.8 1 0 0 1 1 1 1 Transmembrane protein 51 Herpes_gE PF02480.11 AEO55123.1 - 0.038 12.2 0.0 0.07 11.3 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E FAM176 PF14851.1 AEO55123.1 - 0.063 12.9 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 FAM176 family Vpu PF00558.14 AEO55123.1 - 0.1 12.1 0.1 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Vpu protein Shisa PF13908.1 AEO55123.1 - 0.15 12.2 0.0 0.15 12.2 0.0 2.6 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator F-box-like PF12937.2 AEO55125.1 - 8.6e-08 31.7 0.1 1.5e-07 31.0 0.1 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 AEO55125.1 - 5.9e-07 28.9 0.0 2.2e-06 27.1 0.0 1.9 2 0 0 2 2 2 1 F-box domain UIM PF02809.15 AEO55125.1 - 0.0021 17.4 17.4 0.031 13.8 2.0 3.8 3 0 0 3 3 3 2 Ubiquitin interaction motif WD40 PF00400.27 AEO55125.1 - 0.081 12.8 0.0 0.73 9.8 0.0 2.7 3 0 0 3 3 3 0 WD domain, G-beta repeat DUF3597 PF12200.3 AEO55126.1 - 1 9.7 4.2 2.5 8.4 2.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) CAP_N PF01213.14 AEO55126.1 - 4.2 6.5 7.2 0.9 8.7 2.7 1.5 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Clr2 PF10383.4 AEO55127.1 - 6.8e-26 90.9 0.0 1.3e-25 90.0 0.0 1.5 1 0 0 1 1 1 1 Transcription-silencing protein Clr2 DUF605 PF04652.11 AEO55127.1 - 0.47 9.8 9.6 0.36 10.1 2.9 2.1 2 0 0 2 2 2 0 Vta1 like SUN PF03856.8 AEO55128.1 - 1.4e-73 247.2 8.3 1.8e-73 246.9 5.7 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) DUF605 PF04652.11 AEO55128.1 - 1.9 7.7 22.7 3.1 7.1 15.7 1.2 1 0 0 1 1 1 0 Vta1 like TPR_12 PF13424.1 AEO55129.1 - 0.16 11.8 2.4 0.19 11.6 0.1 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 AEO55129.1 - 1.3 9.0 4.2 0.84 9.7 0.4 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Thiolase_N PF00108.18 AEO55130.1 - 1.9e-93 312.3 0.3 2.9e-93 311.6 0.2 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 AEO55130.1 - 3.4e-38 129.8 0.7 8.4e-38 128.5 0.5 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 AEO55130.1 - 0.0005 19.6 0.5 0.0013 18.2 0.1 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain UQ_con PF00179.21 AEO55131.1 - 1.1e-51 173.9 0.1 1.2e-51 173.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AEO55131.1 - 8.7e-07 28.7 0.0 1e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 AEO55131.1 - 0.027 14.3 0.2 0.054 13.3 0.1 1.6 1 1 0 1 1 1 0 RWD domain Kinesin PF00225.18 AEO55132.1 - 7.6e-113 376.6 0.9 1.9e-112 375.2 0.6 1.7 1 0 0 1 1 1 1 Kinesin motor domain ERM PF00769.14 AEO55132.1 - 0.0021 17.6 22.9 0.0021 17.6 15.9 3.5 2 1 1 3 3 3 2 Ezrin/radixin/moesin family adh_short PF00106.20 AEO55134.1 - 9.1e-24 84.2 0.0 1.1e-23 83.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO55134.1 - 5.5e-09 36.1 0.0 7.6e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO55134.1 - 1.4e-08 34.5 0.0 2e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 AEO55134.1 - 0.0025 17.2 0.2 0.014 14.7 0.0 2.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 AEO55134.1 - 0.0093 15.7 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3HCDH_N PF02737.13 AEO55134.1 - 0.065 12.8 0.1 0.087 12.4 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 AEO55134.1 - 0.12 12.3 0.0 0.41 10.6 0.1 1.7 2 0 0 2 2 2 0 NADH(P)-binding LCM PF04072.9 AEO55135.1 - 2.3e-22 79.4 0.0 8.7e-22 77.5 0.0 1.8 2 0 0 2 2 2 1 Leucine carboxyl methyltransferase TFIID-18kDa PF02269.11 AEO55136.1 - 1.7e-26 91.8 0.5 4.9e-25 87.1 0.0 2.6 3 0 0 3 3 3 1 Transcription initiation factor IID, 18kD subunit Myc_N PF01056.13 AEO55136.1 - 0.033 13.3 0.5 0.049 12.8 0.3 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Ist1 PF03398.9 AEO55137.1 - 7.8e-67 223.7 1.9 1e-66 223.4 1.3 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway zf-CCHC_2 PF13696.1 AEO55138.1 - 4.8e-12 45.1 9.8 6.1e-06 25.6 1.3 2.5 2 0 0 2 2 2 2 Zinc knuckle Phage_tail_2 PF06199.6 AEO55138.1 - 0.11 12.5 1.5 0.69 9.9 0.3 2.2 2 0 0 2 2 2 0 Phage major tail protein 2 zf-CCHC PF00098.18 AEO55138.1 - 1.7 8.7 11.8 0.099 12.6 4.2 2.0 2 0 0 2 2 2 0 Zinc knuckle Clat_adaptor_s PF01217.15 AEO55139.1 - 4.2e-57 191.8 2.0 4.6e-57 191.7 1.4 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain MFS_1 PF07690.11 AEO55140.1 - 8.3e-22 77.3 37.6 1.6e-19 69.8 18.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 AEO55140.1 - 2.7e-11 43.1 4.8 2.7e-11 43.1 3.3 1.8 2 0 0 2 2 2 1 Nodulin-like Serinc PF03348.10 AEO55141.1 - 1.2e-177 590.9 6.4 1.5e-177 590.6 4.4 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Cys_Met_Meta_PP PF01053.15 AEO55142.1 - 6.1e-140 465.8 0.0 7.1e-140 465.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 AEO55142.1 - 2.2e-07 29.9 0.0 5e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 AEO55142.1 - 9.8e-07 28.1 0.1 4.8e-06 25.8 0.0 1.9 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 AEO55142.1 - 7.6e-06 25.1 0.0 1.2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.6 AEO55142.1 - 1.3e-05 23.7 0.1 3.4e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.11 AEO55142.1 - 0.0013 17.5 0.1 0.0027 16.4 0.0 1.6 1 0 0 1 1 1 1 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 AEO55142.1 - 0.0024 17.0 0.1 0.0061 15.7 0.1 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase POTRA_2 PF08479.6 AEO55142.1 - 0.017 14.7 0.0 0.042 13.5 0.0 1.6 1 0 0 1 1 1 0 POTRA domain, ShlB-type AAA PF00004.24 AEO55143.1 - 7.6e-39 132.9 0.0 1.3e-38 132.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 AEO55143.1 - 4.7e-06 26.7 0.9 0.00016 21.7 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_14 PF13173.1 AEO55143.1 - 6.3e-06 26.1 0.0 1.3e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 AEO55143.1 - 1.2e-05 25.4 0.1 0.001 19.1 0.0 2.4 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 AEO55143.1 - 1.8e-05 23.9 0.0 3e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 AEO55143.1 - 2.1e-05 25.3 0.1 0.00011 22.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 AEO55143.1 - 2.9e-05 23.8 0.1 0.00029 20.5 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 AEO55143.1 - 5.8e-05 23.0 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 AEO55143.1 - 0.00089 18.7 0.3 0.0016 17.8 0.0 1.6 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 AEO55143.1 - 0.00096 19.0 0.0 0.0023 17.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 AEO55143.1 - 0.0011 18.4 0.4 0.11 11.9 0.1 2.6 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 AEO55143.1 - 0.0013 18.4 0.5 0.006 16.3 0.1 2.2 2 0 0 2 2 2 1 Part of AAA domain Mg_chelatase PF01078.16 AEO55143.1 - 0.0014 17.8 0.1 0.0026 16.9 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 AEO55143.1 - 0.0018 17.3 0.0 0.0044 16.1 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin Sigma54_activ_2 PF14532.1 AEO55143.1 - 0.0025 17.8 0.0 0.0057 16.7 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain RNA_helicase PF00910.17 AEO55143.1 - 0.0047 17.0 0.0 0.012 15.8 0.0 1.8 1 0 0 1 1 1 1 RNA helicase NACHT PF05729.7 AEO55143.1 - 0.0055 16.3 0.0 0.015 14.9 0.0 1.7 1 1 1 2 2 2 1 NACHT domain Oxidored_nitro PF00148.14 AEO55143.1 - 0.0057 15.3 0.0 0.037 12.6 0.0 1.9 2 0 0 2 2 2 1 Nitrogenase component 1 type Oxidoreductase AAA_28 PF13521.1 AEO55143.1 - 0.0068 16.3 0.3 0.051 13.5 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 AEO55143.1 - 0.014 15.6 0.1 0.075 13.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 AEO55143.1 - 0.018 14.6 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 AEO55143.1 - 0.02 14.3 0.0 0.05 13.0 0.0 1.6 2 0 0 2 2 1 0 Sigma-54 interaction domain DUF815 PF05673.8 AEO55143.1 - 0.021 13.7 0.0 0.037 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 AEO55143.1 - 0.023 14.3 0.0 0.14 11.8 0.0 2.0 1 1 1 2 2 2 0 Archaeal ATPase NB-ARC PF00931.17 AEO55143.1 - 0.038 12.8 0.0 0.064 12.1 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain UPF0542 PF15086.1 AEO55143.1 - 0.039 13.6 0.0 0.074 12.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 Viral_helicase1 PF01443.13 AEO55143.1 - 0.069 12.6 0.0 0.14 11.6 0.0 1.5 2 0 0 2 2 1 0 Viral (Superfamily 1) RNA helicase TIP49 PF06068.8 AEO55143.1 - 0.072 11.8 0.0 0.12 11.0 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus Bac_DnaA PF00308.13 AEO55143.1 - 0.08 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein PGA2 PF07543.7 AEO55143.1 - 0.096 12.4 0.1 0.096 12.4 0.1 2.4 2 1 0 2 2 2 0 Protein trafficking PGA2 ABC_tran PF00005.22 AEO55143.1 - 0.099 12.9 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Parvo_NS1 PF01057.12 AEO55143.1 - 0.11 11.4 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 KaiC PF06745.8 AEO55143.1 - 0.13 11.3 0.0 0.69 8.9 0.0 1.9 1 1 1 2 2 2 0 KaiC Rad17 PF03215.10 AEO55143.1 - 0.19 10.4 0.0 0.28 9.8 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Csm1 PF12539.3 AEO55144.1 - 1.1e-26 93.0 0.0 2.4e-26 92.0 0.0 1.6 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 ERM PF00769.14 AEO55144.1 - 0.00048 19.7 13.0 0.001 18.6 9.0 1.5 1 0 0 1 1 1 1 Ezrin/radixin/moesin family AAA_13 PF13166.1 AEO55144.1 - 0.0019 16.7 10.2 0.0027 16.2 7.1 1.1 1 0 0 1 1 1 1 AAA domain EzrA PF06160.7 AEO55144.1 - 0.0072 14.5 7.1 0.01 14.0 4.9 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA NPV_P10 PF05531.7 AEO55144.1 - 0.021 15.0 1.1 0.58 10.4 0.9 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.6 AEO55144.1 - 0.033 12.8 12.9 0.048 12.3 8.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.4 AEO55144.1 - 0.039 13.8 15.5 0.13 12.1 3.2 2.3 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rootletin PF15035.1 AEO55144.1 - 0.043 13.8 10.3 0.079 12.9 7.2 1.4 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Bap31 PF05529.7 AEO55144.1 - 0.057 12.8 8.5 0.15 11.5 5.9 1.8 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Coleoptericin PF06286.6 AEO55144.1 - 0.069 13.0 2.2 0.4 10.5 0.0 2.3 2 0 0 2 2 2 0 Coleoptericin HlyD_2 PF12700.2 AEO55144.1 - 0.11 11.5 4.9 0.17 11.0 3.4 1.2 1 0 0 1 1 1 0 HlyD family secretion protein DUF3584 PF12128.3 AEO55144.1 - 0.12 9.6 14.3 0.16 9.2 9.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) V_ATPase_I PF01496.14 AEO55144.1 - 0.17 9.6 3.7 0.24 9.2 2.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Phlebovirus_NSM PF07246.6 AEO55144.1 - 0.39 9.8 6.7 0.59 9.2 4.7 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M FimP PF09766.4 AEO55144.1 - 1.1 8.2 10.0 1.8 7.5 6.9 1.3 1 0 0 1 1 1 0 Fms-interacting protein ADIP PF11559.3 AEO55144.1 - 1.4 8.7 18.0 1.3 8.9 7.1 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Fib_alpha PF08702.5 AEO55144.1 - 1.6 8.8 8.1 6.8 6.8 5.1 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family FemAB PF02388.11 AEO55144.1 - 2 7.0 7.7 3 6.4 5.3 1.3 1 0 0 1 1 1 0 FemAB family Mnd1 PF03962.10 AEO55144.1 - 2.9 7.5 14.5 6.8 6.3 9.4 2.0 1 1 0 1 1 1 0 Mnd1 family DUF773 PF05600.7 AEO55144.1 - 3.1 6.4 9.3 15 4.1 6.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF773) IncA PF04156.9 AEO55144.1 - 4.4 6.8 17.7 14 5.2 8.5 2.1 1 1 1 2 2 2 0 IncA protein PspA_IM30 PF04012.7 AEO55144.1 - 4.6 6.5 28.6 0.54 9.5 16.7 1.8 2 0 0 2 2 2 0 PspA/IM30 family APG6 PF04111.7 AEO55144.1 - 5.2 6.0 14.7 7.9 5.4 10.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Seryl_tRNA_N PF02403.17 AEO55144.1 - 5.6 7.0 16.6 9 6.3 8.5 2.8 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Matrilin_ccoil PF10393.4 AEO55144.1 - 8.3 5.8 7.4 3 7.2 0.0 3.1 2 1 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin ATG16 PF08614.6 AEO55144.1 - 8.6 6.1 19.3 14 5.3 11.4 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) PGAP1 PF07819.8 AEO55145.1 - 1.7e-87 292.7 0.0 2.4e-87 292.2 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 AEO55145.1 - 6.2e-07 29.2 0.0 1.2e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AEO55145.1 - 1.4e-05 25.0 0.2 2.9e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO55145.1 - 0.0028 17.2 0.0 0.0068 15.9 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.9 AEO55145.1 - 0.013 14.7 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) TMEM173 PF15009.1 AEO55145.1 - 0.046 12.5 3.1 0.74 8.5 2.5 2.2 2 0 0 2 2 2 0 Transmembrane protein 173 COesterase PF00135.23 AEO55145.1 - 0.059 12.0 0.0 0.086 11.5 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family Esterase PF00756.15 AEO55145.1 - 0.081 12.3 0.0 0.19 11.1 0.0 1.5 2 0 0 2 2 2 0 Putative esterase LCAT PF02450.10 AEO55145.1 - 0.083 11.8 0.0 0.18 10.7 0.0 1.5 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase Lipase_3 PF01764.20 AEO55145.1 - 0.11 12.0 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) MutL_C PF08676.6 AEO55146.1 - 2.8e-22 78.8 0.1 6.8e-22 77.6 0.0 1.6 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 AEO55146.1 - 1.3e-17 63.3 0.0 2.9e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 AEO55146.1 - 6.6e-12 45.2 0.0 1.7e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 AEO55146.1 - 2e-11 43.5 0.0 4.8e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Bacteriocin_IId PF09221.5 AEO55147.1 - 0.43 10.5 6.9 1.2 9.0 4.8 1.7 1 0 0 1 1 1 0 Bacteriocin class IId cyclical uberolysin-like DUF4244 PF14029.1 AEO55147.1 - 2.8 7.0 7.0 6.7 5.8 4.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4244) Pyr_redox_3 PF13738.1 AEO55148.1 - 2.4e-05 24.5 0.0 0.0006 19.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 AEO55148.1 - 0.00014 21.7 0.0 0.0011 18.8 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AEO55148.1 - 0.0033 17.4 0.0 0.0078 16.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 AEO55148.1 - 0.027 12.9 0.0 0.085 11.3 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.1 AEO55148.1 - 0.11 12.2 0.1 0.5 10.1 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding ETF PF01012.16 AEO55149.1 - 2.4e-41 141.2 0.6 5e-41 140.1 0.4 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 AEO55149.1 - 1.1e-36 124.3 0.3 3.2e-36 122.8 0.2 1.8 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain SWIRM PF04433.12 AEO55150.1 - 1.5e-35 121.1 0.1 2.9e-35 120.2 0.1 1.5 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 AEO55150.1 - 1.2e-07 31.6 0.0 2.8e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 AEO55150.1 - 0.00017 21.6 0.5 0.00042 20.3 0.4 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF3439 PF11921.3 AEO55150.1 - 0.0002 21.1 6.2 0.00041 20.0 4.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Mucin PF01456.12 AEO55150.1 - 0.00039 20.2 13.0 0.00039 20.2 9.0 2.7 3 0 0 3 3 3 1 Mucin-like glycoprotein SSP160 PF06933.6 AEO55150.1 - 0.0045 15.0 10.9 0.0062 14.5 7.6 1.1 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 ZZ PF00569.12 AEO55150.1 - 0.018 14.5 3.6 0.038 13.5 2.5 1.5 1 0 0 1 1 1 0 Zinc finger, ZZ type Dicty_REP PF05086.7 AEO55150.1 - 3.5 5.2 6.7 5.1 4.7 4.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein TMEM154 PF15102.1 AEO55150.1 - 3.7 7.2 6.4 8.9 6.0 4.5 1.6 1 0 0 1 1 1 0 TMEM154 protein family CAP_N PF01213.14 AEO55151.1 - 2.4e-80 270.1 16.8 2.4e-80 270.1 11.6 1.8 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 AEO55151.1 - 4.5e-55 185.3 3.0 6.6e-55 184.8 2.1 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal DUF2360 PF10152.4 AEO55151.1 - 0.032 14.5 1.4 0.032 14.5 1.0 3.3 2 1 1 3 3 3 0 Predicted coiled-coil domain-containing protein (DUF2360) TBCC PF07986.7 AEO55151.1 - 0.25 10.7 2.1 0.79 9.1 1.0 1.8 1 1 1 2 2 2 0 Tubulin binding cofactor C PfkB PF00294.19 AEO55152.1 - 8.7e-16 57.9 0.1 5.3e-09 35.6 0.3 2.2 2 0 0 2 2 2 2 pfkB family carbohydrate kinase MCM PF00493.18 AEO55153.1 - 4.4e-131 436.5 0.4 7e-131 435.9 0.3 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 AEO55153.1 - 2.5e-15 57.0 0.0 2.2e-14 53.9 0.0 2.4 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 AEO55153.1 - 2.7e-07 29.9 0.0 3.4e-06 26.3 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 AEO55153.1 - 0.0018 17.8 0.0 0.0061 16.1 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 AEO55153.1 - 0.009 15.4 0.0 0.026 13.9 0.0 1.7 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF3801 PF12687.2 AEO55153.1 - 0.17 11.3 5.4 5.7 6.4 0.8 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3801) Aminotran_3 PF00202.16 AEO55154.1 - 4.1e-84 282.3 0.0 4.9e-84 282.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 AEO55154.1 - 0.0092 14.9 0.0 0.016 14.1 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Exo70 PF03081.10 AEO55155.1 - 1.6e-71 241.0 0.0 2.8e-71 240.2 0.0 1.4 1 0 0 1 1 1 1 Exo70 exocyst complex subunit PLC-beta_C PF08703.5 AEO55155.1 - 0.005 16.5 0.3 0.11 12.1 0.0 2.7 2 0 0 2 2 2 1 PLC-beta C terminal Baculo_PEP_C PF04513.7 AEO55155.1 - 0.07 12.9 5.9 1.6 8.5 0.1 3.5 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin PF00804.20 AEO55155.1 - 0.41 10.8 9.6 2.2 8.4 0.3 3.5 3 0 0 3 3 3 0 Syntaxin Apolipoprotein PF01442.13 AEO55155.1 - 1 8.7 5.8 1 8.8 0.0 2.9 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Acetone_carb_G PF08882.6 AEO55156.1 - 0.018 15.0 0.2 0.02 14.9 0.1 1.1 1 0 0 1 1 1 0 Acetone carboxylase gamma subunit DUF1399 PF07173.7 AEO55157.1 - 3.8e-15 56.3 1.7 4.9e-12 46.2 0.1 4.4 4 1 1 5 5 5 3 Protein of unknown function (DUF1399) Methyltransf_2 PF00891.13 AEO55158.1 - 2.6e-27 95.5 0.0 4e-27 94.9 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 AEO55158.1 - 0.01 15.5 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Fe-ADH_2 PF13685.1 AEO55158.1 - 0.065 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase DUF3989 PF13150.1 AEO55159.1 - 0.27 10.7 2.4 0.9 9.0 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3989) FAA_hydrolase PF01557.13 AEO55160.1 - 1.7e-51 174.7 0.0 2.4e-51 174.2 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family BRO1 PF03097.13 AEO55161.1 - 2.6e-134 447.7 2.3 2.6e-134 447.7 1.6 2.4 3 0 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 AEO55161.1 - 1.8e-84 283.2 19.2 4e-84 282.0 13.3 1.6 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Pox_E2-like PF04497.7 AEO55161.1 - 0.036 12.1 0.6 0.056 11.4 0.4 1.2 1 0 0 1 1 1 0 Poxviridae protein DUF1539 PF07560.6 AEO55161.1 - 1.2 9.0 6.4 0.92 9.3 0.0 3.2 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1539) Fungal_trans PF04082.13 AEO55162.1 - 3.2e-36 124.5 0.0 1.1e-35 122.7 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO55162.1 - 3e-08 33.4 8.6 5.1e-08 32.6 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dna2 PF08696.6 AEO55162.1 - 0.09 12.0 0.2 0.19 11.0 0.1 1.4 1 0 0 1 1 1 0 DNA replication factor Dna2 PigN PF04987.9 AEO55163.1 - 1e-165 551.6 22.0 1.5e-165 551.1 15.2 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 AEO55163.1 - 6.6e-11 42.1 1.0 4.1e-09 36.2 0.7 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 AEO55163.1 - 8.4e-08 31.7 0.1 1.3e-07 31.1 0.1 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 AEO55163.1 - 3.4e-05 23.3 0.0 5.5e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Alk_phosphatase PF00245.15 AEO55163.1 - 0.013 14.2 0.1 0.02 13.5 0.0 1.2 1 0 0 1 1 1 0 Alkaline phosphatase CDC27 PF09507.5 AEO55164.1 - 2.3e-97 326.9 24.4 2.7e-97 326.7 16.9 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 DUF1237 PF06824.6 AEO55165.1 - 3.8e-181 602.3 0.0 4.4e-181 602.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) EnY2 PF10163.4 AEO55165.1 - 0.08 12.8 0.1 0.25 11.2 0.1 1.9 1 0 0 1 1 1 0 Transcription factor e(y)2 FSH1 PF03959.8 AEO55166.1 - 3e-27 95.4 0.0 2.5e-26 92.4 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 AEO55166.1 - 5.7e-07 29.6 0.0 7.6e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 AEO55166.1 - 0.018 14.4 0.0 0.063 12.7 0.0 1.9 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Carn_acyltransf PF00755.15 AEO55168.1 - 3.2e-179 596.8 0.0 3.6e-179 596.6 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Syja_N PF02383.13 AEO55169.1 - 6e-89 297.9 0.0 1.3e-88 296.8 0.0 1.5 1 0 0 1 1 1 1 SacI homology domain FAM196 PF15265.1 AEO55169.1 - 0.13 11.4 11.8 0.22 10.7 8.2 1.2 1 0 0 1 1 1 0 FAM196 family DUF2454 PF10521.4 AEO55170.1 - 2.8e-61 207.0 0.0 4.4e-61 206.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) HD_5 PF13487.1 AEO55170.1 - 0.0098 15.8 0.1 0.039 13.9 0.0 2.1 2 0 0 2 2 2 1 HD domain DUF4129 PF13559.1 AEO55170.1 - 0.27 11.2 3.4 0.25 11.3 0.6 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4129) PolyA_pol PF01743.15 AEO55171.1 - 1.1e-23 83.8 0.1 3.6e-23 82.1 0.1 1.9 1 1 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 AEO55171.1 - 2e-08 33.7 0.0 4.7e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 AEO55171.1 - 0.083 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative Stimulus_sens_1 PF13756.1 AEO55172.1 - 0.031 14.6 0.1 0.033 14.5 0.1 1.1 1 0 0 1 1 1 0 Stimulus-sensing domain Sec7 PF01369.15 AEO55173.1 - 3.2e-59 199.8 0.0 5.1e-59 199.1 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 AEO55173.1 - 4e-18 65.4 0.1 1e-10 41.2 0.0 3.6 4 0 0 4 4 4 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Anp1 PF03452.9 AEO55174.1 - 4.8e-123 409.5 0.2 1.7e-122 407.8 0.0 1.8 2 0 0 2 2 2 1 Anp1 RNase_PH PF01138.16 AEO55175.1 - 2.9e-25 89.0 0.0 4.7e-25 88.4 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 GDA1_CD39 PF01150.12 AEO55176.1 - 2.2e-104 349.3 0.0 3.1e-104 348.8 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family PPV_E2_C PF00511.12 AEO55176.1 - 0.083 12.8 0.0 0.25 11.3 0.0 1.8 1 0 0 1 1 1 0 E2 (early) protein, C terminal DUF775 PF05603.7 AEO55177.1 - 7.6e-50 169.2 0.0 8.8e-50 169.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) NUDIX PF00293.23 AEO55178.1 - 3.5e-07 29.9 0.0 6.5e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain RNA_pol_Rpb8 PF03870.10 AEO55179.1 - 3.5e-23 82.3 0.1 4e-23 82.1 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 PAXNEB PF05625.6 AEO55180.1 - 4.6e-103 344.8 0.0 5.2e-103 344.6 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein tRNA_int_endo PF01974.12 AEO55181.1 - 1.2e-15 57.0 0.0 2.8e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain IL33 PF15095.1 AEO55181.1 - 0.13 11.6 0.3 0.18 11.2 0.2 1.1 1 0 0 1 1 1 0 Interleukin 33 zf-C3HC4_3 PF13920.1 AEO55182.1 - 6.9e-08 32.0 13.0 1.1e-07 31.3 9.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PhrC_PhrF PF11131.3 AEO55182.1 - 0.01 15.4 0.2 0.033 13.7 0.1 1.9 1 0 0 1 1 1 0 Rap-phr extracellular signalling Nop14 PF04147.7 AEO55182.1 - 0.93 7.3 2.1 1.3 6.8 1.5 1.1 1 0 0 1 1 1 0 Nop14-like family FAM24 PF15193.1 AEO55182.1 - 3.2 8.0 9.3 6.7 6.9 6.5 1.5 1 0 0 1 1 1 0 FAM24 family RRM_1 PF00076.17 AEO55183.1 - 5.6e-26 89.9 0.3 4.2e-12 45.5 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO55183.1 - 1.4e-15 57.0 0.1 1.6e-06 28.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO55183.1 - 1.5e-13 50.3 0.1 4e-08 32.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 AEO55183.1 - 0.071 12.8 0.0 17 5.2 0.0 2.7 2 1 1 3 3 3 0 Limkain b1 Suf PF05843.9 AEO55184.1 - 1.6e-11 44.4 11.8 0.021 14.5 4.5 6.1 3 2 2 5 5 5 2 Suppressor of forked protein (Suf) TPR_12 PF13424.1 AEO55184.1 - 4.6e-11 42.5 1.2 0.38 10.7 0.0 7.8 8 1 0 8 8 8 2 Tetratricopeptide repeat TPR_11 PF13414.1 AEO55184.1 - 3.8e-07 29.6 5.4 0.15 11.7 0.0 6.9 8 0 0 8 8 8 2 TPR repeat TPR_14 PF13428.1 AEO55184.1 - 3.3e-06 27.2 19.8 3.5 8.5 0.0 10.7 12 2 2 14 14 11 1 Tetratricopeptide repeat TPR_15 PF13429.1 AEO55184.1 - 6.9e-06 25.3 18.9 0.00021 20.4 1.4 5.4 3 2 2 5 5 5 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 AEO55184.1 - 4.5e-05 23.2 8.4 1.5 8.6 0.1 6.7 7 0 0 7 7 7 2 Mad3/BUB1 homology region 1 NRDE-2 PF08424.5 AEO55184.1 - 6.5e-05 21.9 12.9 0.0032 16.3 0.9 6.1 2 2 2 4 4 4 1 NRDE-2, necessary for RNA interference RPN7 PF10602.4 AEO55184.1 - 0.00024 20.5 1.1 0.001 18.5 0.1 2.6 3 1 0 3 3 3 1 26S proteasome subunit RPN7 TPR_16 PF13432.1 AEO55184.1 - 0.0012 19.4 13.8 0.073 13.7 0.0 7.1 9 1 0 9 9 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 AEO55184.1 - 0.011 15.4 4.9 0.87 9.5 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat PPR_3 PF13812.1 AEO55184.1 - 0.058 13.6 0.0 1.5 9.3 0.0 3.4 2 0 0 2 2 2 0 Pentatricopeptide repeat domain Clathrin PF00637.15 AEO55184.1 - 0.14 11.7 4.9 27 4.3 0.1 4.7 5 0 0 5 5 5 0 Region in Clathrin and VPS TPR_2 PF07719.12 AEO55184.1 - 0.17 11.9 22.1 4.3 7.5 0.0 7.2 10 0 0 10 10 7 0 Tetratricopeptide repeat TPR_17 PF13431.1 AEO55184.1 - 0.46 10.8 4.5 19 5.7 0.0 5.5 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 AEO55184.1 - 3.7 8.1 7.6 30 5.3 0.0 6.0 5 1 1 6 6 5 0 Tetratricopeptide repeat Tannase PF07519.6 AEO55185.1 - 0.12 11.0 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Tannase and feruloyl esterase adh_short PF00106.20 AEO55186.1 - 1.2e-34 119.6 0.4 3.1e-34 118.2 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO55186.1 - 1e-13 51.6 0.0 1.3e-13 51.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO55186.1 - 1.4e-13 50.8 0.0 2.6e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 AEO55186.1 - 0.026 13.4 0.0 0.05 12.4 0.0 1.6 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 AEO55186.1 - 0.043 13.6 0.1 0.082 12.7 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Lin0512_fam PF09585.5 AEO55186.1 - 0.048 13.2 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical protein (Lin0512_fam) PrgI PF12666.2 AEO55187.1 - 0.0085 16.2 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 PrgI family protein Metal_resist PF13801.1 AEO55187.1 - 0.04 13.8 3.6 0.2 11.6 0.0 2.1 2 0 0 2 2 2 0 Heavy-metal resistance Trp_oprn_chp PF09534.5 AEO55187.1 - 0.047 13.3 0.4 0.046 13.3 0.3 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) MFS_1 PF07690.11 AEO55189.1 - 8.2e-12 44.4 8.5 1.1e-11 44.1 5.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO55189.1 - 0.00015 20.4 5.7 0.00019 20.1 3.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Fungal_trans PF04082.13 AEO55191.1 - 7.7e-30 103.6 0.1 1.5e-29 102.6 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ThiF PF00899.16 AEO55192.1 - 7.9e-11 41.9 0.0 3.4e-10 39.8 0.0 2.0 2 0 0 2 2 2 1 ThiF family ATG16 PF08614.6 AEO55193.1 - 0.007 16.2 0.8 0.0093 15.8 0.6 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Mod_r PF07200.8 AEO55193.1 - 0.012 15.5 1.2 0.018 14.9 0.8 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein FTO_CTD PF12934.2 AEO55193.1 - 0.061 12.8 0.2 0.077 12.5 0.2 1.2 1 0 0 1 1 1 0 FTO C-terminal domain FUSC PF04632.7 AEO55193.1 - 0.069 11.5 0.7 0.095 11.1 0.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Bacillus_HBL PF05791.6 AEO55193.1 - 0.095 12.0 0.4 0.14 11.5 0.3 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Terminase_2 PF03592.11 AEO55193.1 - 0.12 12.7 0.1 0.17 12.1 0.1 1.2 1 0 0 1 1 1 0 Terminase small subunit IncA PF04156.9 AEO55193.1 - 0.26 10.8 8.1 0.41 10.2 5.6 1.2 1 0 0 1 1 1 0 IncA protein DZR PF12773.2 AEO55193.1 - 0.35 10.7 3.1 0.79 9.5 2.2 1.6 1 0 0 1 1 1 0 Double zinc ribbon CALCOCO1 PF07888.6 AEO55193.1 - 0.36 9.0 3.7 0.47 8.6 2.5 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DivIC PF04977.10 AEO55193.1 - 3.2 7.3 5.0 6.3 6.3 0.2 2.6 1 1 2 3 3 3 0 Septum formation initiator PEMT PF04191.8 AEO55194.1 - 1.3e-56 189.2 16.2 6.4e-37 125.8 1.3 2.9 3 0 0 3 3 3 2 Phospholipid methyltransferase FAD_oxidored PF12831.2 AEO55195.1 - 0.018 14.1 0.7 0.022 13.8 0.5 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase TFIIA PF03153.8 AEO55195.1 - 0.038 13.8 4.5 0.038 13.8 3.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TP2 PF01254.13 AEO55195.1 - 0.4 11.0 7.2 0.75 10.1 5.0 1.5 1 0 0 1 1 1 0 Nuclear transition protein 2 Ndc1_Nup PF09531.5 AEO55195.1 - 0.81 8.0 3.6 1.1 7.6 2.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup eIF3g PF12353.3 AEO55196.1 - 6.6e-46 155.3 0.9 1.1e-45 154.6 0.6 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 AEO55196.1 - 1.4e-16 59.8 0.1 2.8e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO55196.1 - 7.8e-13 48.2 0.1 1.5e-12 47.3 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO55196.1 - 6e-08 32.4 0.0 1.5e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2782 PF11191.3 AEO55196.1 - 0.012 15.5 0.4 0.023 14.6 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2782) DUF2046 PF09755.4 AEO55198.1 - 0.0028 16.5 3.0 0.0028 16.5 2.1 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) FlxA PF14282.1 AEO55198.1 - 0.056 13.3 14.1 0.11 12.4 3.7 2.4 2 0 0 2 2 2 0 FlxA-like protein IncA PF04156.9 AEO55198.1 - 0.36 10.3 6.2 3.8 7.0 1.1 2.2 2 0 0 2 2 2 0 IncA protein DUF3573 PF12097.3 AEO55198.1 - 0.74 8.3 2.5 3 6.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) Pox_A_type_inc PF04508.7 AEO55198.1 - 0.98 9.3 5.2 1.2 9.1 0.1 2.9 2 1 1 3 3 3 0 Viral A-type inclusion protein repeat Fib_alpha PF08702.5 AEO55198.1 - 3.7 7.6 6.8 4.4 7.4 0.5 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF3664 PF12406.3 AEO55198.1 - 7.3 7.2 8.9 0.55 10.8 2.3 1.9 2 0 0 2 2 2 0 Surface protein DAO PF01266.19 AEO55199.1 - 2.7e-49 167.9 2.2 3.2e-49 167.7 1.5 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AEO55199.1 - 0.0073 16.3 0.4 0.028 14.4 0.3 2.0 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_Gly3P_dh_N PF01210.18 AEO55199.1 - 0.1 12.3 0.0 0.44 10.2 0.0 2.0 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF2415 PF10313.4 AEO55200.1 - 6.7e-15 54.4 0.0 1.8e-14 53.1 0.0 1.8 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) Atg14 PF10186.4 AEO55200.1 - 0.24 10.2 0.0 0.36 9.7 0.0 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Halo_GVPC PF05465.8 AEO55200.1 - 1.1 9.2 4.0 0.48 10.4 0.1 2.5 3 0 0 3 3 3 0 Halobacterial gas vesicle protein C (GVPC) repeat HSP70 PF00012.15 AEO55201.1 - 2e-268 891.2 17.2 2.4e-268 891.0 11.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 AEO55201.1 - 3.3e-16 58.8 4.6 4.1e-14 51.9 0.9 2.6 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 AEO55201.1 - 2.3e-05 24.0 0.6 0.00084 19.0 0.0 2.6 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 AEO55201.1 - 0.0026 17.5 11.3 0.21 11.4 0.0 4.7 2 2 2 4 4 4 2 Cell division protein FtsA DUF4363 PF14276.1 AEO55201.1 - 0.13 11.9 4.3 0.29 10.8 3.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) DnaG_DnaB_bind PF08278.6 AEO55201.1 - 0.25 11.5 4.1 0.29 11.3 1.7 2.2 2 0 0 2 2 2 0 DNA primase DnaG DnaB-binding Ank PF00023.25 AEO55203.1 - 2.8e-29 99.4 4.6 1.4e-06 27.8 0.0 5.9 5 0 0 5 5 5 5 Ankyrin repeat Ank_2 PF12796.2 AEO55203.1 - 3.8e-28 97.6 0.1 7.8e-12 45.3 0.0 5.3 3 2 0 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.1 AEO55203.1 - 3.5e-25 85.5 1.0 0.00038 20.4 0.0 6.3 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 AEO55203.1 - 2.1e-23 82.2 1.9 9.8e-08 32.3 0.0 6.3 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 AEO55203.1 - 2.4e-15 56.1 2.9 0.0015 18.7 0.0 6.6 5 3 2 7 7 7 4 Ankyrin repeats (many copies) Sel1 PF08238.7 AEO55203.1 - 0.047 14.3 0.0 0.21 12.2 0.0 2.2 1 0 0 1 1 1 0 Sel1 repeat HeLo PF14479.1 AEO55205.1 - 5.2e-15 55.7 0.0 6.1e-15 55.5 0.0 1.0 1 0 0 1 1 1 1 Prion-inhibition and propagation PPR_2 PF13041.1 AEO55206.1 - 1.5e-17 63.2 2.5 8e-06 25.7 0.0 6.4 3 1 4 7 7 7 4 PPR repeat family PPR PF01535.15 AEO55206.1 - 3.1e-13 48.7 3.1 0.0031 17.3 0.1 8.3 8 0 0 8 8 8 2 PPR repeat PPR_3 PF13812.1 AEO55206.1 - 4.5e-10 38.9 13.9 0.26 11.6 0.0 8.6 9 0 0 9 9 9 4 Pentatricopeptide repeat domain PPR_1 PF12854.2 AEO55206.1 - 3.7e-06 26.3 0.0 0.29 10.6 0.0 3.7 3 0 0 3 3 3 2 PPR repeat TPR_14 PF13428.1 AEO55206.1 - 2e-05 24.7 4.3 8.5 7.3 0.0 7.2 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.1 AEO55206.1 - 0.0002 21.6 0.1 1.3 9.3 0.1 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat ATP13 PF12921.2 AEO55206.1 - 0.0017 17.7 0.0 0.25 10.7 0.0 2.8 2 0 0 2 2 2 1 Mitochondrial ATPase expression TPR_2 PF07719.12 AEO55206.1 - 0.71 9.9 4.2 83 3.4 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat RRM_6 PF14259.1 AEO55207.1 - 3.5e-11 42.9 0.1 8.7e-11 41.6 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO55207.1 - 3.8e-09 36.2 0.2 9.6e-09 34.9 0.1 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 AEO55207.1 - 4.5e-08 32.5 3.7 8.2e-08 31.7 2.5 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.17 AEO55207.1 - 3.1e-07 29.9 0.9 1.5e-06 27.7 0.1 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 AEO55207.1 - 7.3e-07 29.2 0.0 1.8e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 PWI domain Nup35_RRM_2 PF14605.1 AEO55207.1 - 7.8e-05 22.3 0.0 0.052 13.3 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif DUF1330 PF07045.6 AEO55207.1 - 0.049 13.5 0.1 0.88 9.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1330) ArsC PF03960.10 AEO55207.1 - 0.32 11.0 3.9 2.5 8.2 0.0 2.3 2 0 0 2 2 2 0 ArsC family Ycf1 PF05758.7 AEO55207.1 - 3.4 5.2 7.3 6.2 4.3 5.1 1.3 1 0 0 1 1 1 0 Ycf1 V_ATPase_I PF01496.14 AEO55207.1 - 4.2 5.0 6.6 6 4.5 4.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MTHFR PF02219.12 AEO55208.1 - 5.1e-112 373.6 0.0 8e-112 372.9 0.0 1.3 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DUF676 PF05057.9 AEO55209.1 - 1.4e-42 145.4 0.0 1.8e-28 99.3 0.0 3.2 2 1 1 3 3 3 3 Putative serine esterase (DUF676) BSP_II PF05432.6 AEO55209.1 - 0.004 16.4 3.8 0.004 16.4 2.6 2.5 2 0 0 2 2 2 2 Bone sialoprotein II (BSP-II) Abhydrolase_5 PF12695.2 AEO55209.1 - 0.011 15.4 0.0 0.028 14.1 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.20 AEO55209.1 - 0.039 13.5 0.0 0.079 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF915 PF06028.6 AEO55209.1 - 0.051 12.6 0.0 0.088 11.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) PGAP1 PF07819.8 AEO55209.1 - 0.061 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF3597 PF12200.3 AEO55209.1 - 0.34 11.3 4.9 0.91 9.9 0.9 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) CENP-B_dimeris PF09026.5 AEO55209.1 - 1.9 8.7 16.9 0.35 11.1 1.4 3.3 3 0 0 3 3 3 0 Centromere protein B dimerisation domain zf-BED PF02892.10 AEO55210.1 - 0.033 13.9 0.3 0.033 13.9 0.2 2.3 2 0 0 2 2 2 0 BED zinc finger Zn_clus PF00172.13 AEO55210.1 - 0.1 12.5 7.9 0.24 11.3 5.5 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_6 PF13912.1 AEO55210.1 - 0.21 11.5 5.1 0.067 13.1 0.4 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger Sec5 PF15469.1 AEO55211.1 - 5.2e-34 117.5 0.0 1.6e-33 116.0 0.0 1.9 2 0 0 2 2 2 1 Exocyst complex component Sec5 Vps51 PF08700.6 AEO55211.1 - 0.0031 17.3 0.1 0.0031 17.3 0.1 3.0 4 0 0 4 4 4 1 Vps51/Vps67 THOC7 PF05615.8 AEO55211.1 - 0.018 15.2 1.6 0.6 10.3 0.1 2.9 2 0 0 2 2 2 0 Tho complex subunit 7 Iso_dh PF00180.15 AEO55212.1 - 2e-97 326.2 0.0 2.5e-97 325.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase SR-25 PF10500.4 AEO55213.1 - 0.029 13.8 6.7 0.027 13.9 4.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein BSP PF04450.7 AEO55215.1 - 8.7e-79 263.7 0.0 1e-78 263.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase of plants and bacteria Peptidase_MA_2 PF13485.1 AEO55215.1 - 2.7e-08 33.9 0.2 6e-05 23.0 0.0 2.3 1 1 1 2 2 2 2 Peptidase MA superfamily SprT-like PF10263.4 AEO55215.1 - 0.0051 16.4 0.0 0.0095 15.5 0.0 1.4 1 0 0 1 1 1 1 SprT-like family CLASP_N PF12348.3 AEO55216.1 - 8e-133 440.8 1.8 4.8e-87 291.0 0.1 2.8 3 0 0 3 3 3 2 CLASP N terminal HEAT PF02985.17 AEO55216.1 - 0.00022 21.0 0.0 5.4 7.3 0.0 4.8 4 0 0 4 4 4 2 HEAT repeat Vac14_Fab1_bd PF12755.2 AEO55216.1 - 0.0059 16.9 0.0 2.6 8.5 0.0 3.1 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region YozD PF14162.1 AEO55216.1 - 0.081 13.0 0.0 7.6 6.6 0.0 2.6 2 0 0 2 2 2 0 YozD-like protein HEAT_2 PF13646.1 AEO55216.1 - 0.18 12.0 8.9 1 9.6 0.0 4.8 5 1 0 5 5 5 0 HEAT repeats Adaptin_N PF01602.15 AEO55216.1 - 0.2 9.9 0.0 6.2 5.0 0.0 2.5 1 1 0 2 2 2 0 Adaptin N terminal region Sec7_N PF12783.2 AEO55216.1 - 0.21 10.9 0.0 1.5 8.2 0.0 2.4 3 0 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal RhoGAP PF00620.22 AEO55217.1 - 1.4e-45 154.6 0.1 1.4e-45 154.6 0.1 2.7 2 1 0 2 2 2 1 RhoGAP domain LIM PF00412.17 AEO55217.1 - 3.8e-12 46.1 14.2 1.1e-06 28.6 0.2 2.4 2 0 0 2 2 2 2 LIM domain zinc_ribbon_2 PF13240.1 AEO55217.1 - 0.49 9.9 5.9 10 5.7 0.0 4.1 2 2 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 AEO55217.1 - 1.2 9.1 14.1 0.73 9.8 0.8 3.2 3 0 0 3 3 3 0 Zinc ribbon domain V_ATPase_I PF01496.14 AEO55217.1 - 1.7 6.4 6.9 2.5 5.8 4.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-C3HC4_3 PF13920.1 AEO55217.1 - 2.4 7.9 15.8 0.67 9.6 3.7 2.8 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) SlyX PF04102.7 AEO55217.1 - 4.4 7.7 11.2 0.085 13.2 1.1 3.3 2 1 1 3 3 3 0 SlyX TFIIA PF03153.8 AEO55218.1 - 2.2 8.1 30.8 2.8 7.7 21.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4210 PF13915.1 AEO55219.1 - 1.2e-23 83.1 0.1 2.9e-23 81.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 AEO55219.1 - 2.9e-23 81.5 0.8 6.8e-23 80.3 0.6 1.7 1 0 0 1 1 1 1 Chromosome segregation during meiosis GTP_EFTU PF00009.22 AEO55220.1 - 2e-62 209.9 0.0 2.9e-62 209.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 AEO55220.1 - 1e-36 125.0 0.0 2.6e-36 123.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 AEO55220.1 - 8.6e-22 76.8 0.0 2.2e-21 75.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 AEO55220.1 - 6e-13 48.7 2.4 9.7e-13 48.0 0.0 2.6 3 0 0 3 3 3 1 Elongation factor Tu domain 2 EFG_II PF14492.1 AEO55220.1 - 9e-12 44.6 0.0 2.5e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 AEO55220.1 - 1.8e-05 24.6 0.1 3.8e-05 23.6 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Solute_trans_a PF03619.11 AEO55221.1 - 6.3e-66 222.5 0.0 7.3e-66 222.2 0.0 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Na_Ca_ex PF01699.19 AEO55223.1 - 2.5e-42 143.7 33.3 1.7e-22 79.5 7.2 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Rrn6 PF10214.4 AEO55223.1 - 2.2 6.2 4.6 3.1 5.7 3.2 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor YfhO PF09586.5 AEO55223.1 - 4.1 5.2 7.6 0.44 8.5 0.6 2.0 2 0 0 2 2 2 0 Bacterial membrane protein YfhO DUF3608 PF12257.3 AEO55224.1 - 3.1e-74 249.4 0.0 5.5e-74 248.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 AEO55224.1 - 4.3e-30 103.2 0.3 1e-29 102.0 0.1 1.8 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Pkinase_Tyr PF07714.12 AEO55225.1 - 2.3e-13 49.8 0.0 5.6e-12 45.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 AEO55225.1 - 3.9e-11 42.6 0.0 6.4e-11 41.9 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Cation_efflux PF01545.16 AEO55226.1 - 2.4e-67 226.9 7.1 3e-67 226.6 4.9 1.0 1 0 0 1 1 1 1 Cation efflux family LHC PF00556.15 AEO55227.1 - 0.0068 16.2 4.0 0.0068 16.2 2.8 1.4 2 0 0 2 2 2 1 Antenna complex alpha/beta subunit DUF3309 PF11752.3 AEO55227.1 - 2.9 7.7 12.1 1 9.1 6.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3309) FNIP_N PF14636.1 AEO55228.1 - 1.3e-31 109.7 0.2 1.3e-31 109.7 0.1 3.8 3 1 0 3 3 3 1 Folliculin-interacting protein N-terminus FNIP_C PF14638.1 AEO55228.1 - 0.00031 20.1 0.0 0.00063 19.1 0.0 1.4 1 0 0 1 1 1 1 Folliculin-interacting protein C-terminus U79_P34 PF03064.11 AEO55228.1 - 0.14 11.6 10.6 3.3 7.1 3.6 2.3 2 0 0 2 2 2 0 HSV U79 / HCMV P34 TATR PF03430.8 AEO55228.1 - 5.5 5.5 2.2 8.8 4.8 1.5 1.2 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Lactonase PF10282.4 AEO55229.1 - 7.2e-80 268.6 0.0 8e-80 268.4 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Fungal_trans PF04082.13 AEO55230.1 - 2.6e-09 36.3 0.1 2.6e-09 36.3 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO55230.1 - 4e-09 36.2 7.9 4e-09 36.2 5.5 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IBR PF01485.16 AEO55231.1 - 1e-07 31.6 25.2 1.9e-06 27.6 5.5 3.5 3 1 0 3 3 3 2 IBR domain Chorion_2 PF03964.10 AEO55231.1 - 0.01 16.3 1.4 0.01 16.3 1.0 5.6 4 1 1 5 5 5 0 Chorion family 2 DEAD PF00270.24 AEO55232.1 - 2.2e-45 154.1 0.0 2.1e-44 150.9 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO55232.1 - 1.5e-22 79.2 0.1 6.5e-22 77.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 AEO55232.1 - 3.5e-22 77.9 0.4 8.6e-22 76.7 0.3 1.7 1 0 0 1 1 1 1 DBP10CT (NUC160) domain DnaJ PF00226.26 AEO55233.1 - 2.3e-14 52.8 0.7 7.3e-14 51.2 0.2 2.1 2 0 0 2 2 2 1 DnaJ domain TMEM247 PF15444.1 AEO55233.1 - 1.3 8.8 4.7 2.9 7.6 2.9 1.8 1 1 1 2 2 2 0 Transmembrane protein 247 Arm PF00514.18 AEO55234.1 - 0.0065 16.2 0.7 8.3 6.3 0.0 3.3 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat Suf PF05843.9 AEO55234.1 - 0.031 14.0 0.5 0.05 13.3 0.3 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DDHD PF02862.12 AEO55234.1 - 9.1 5.9 7.8 6.6 6.4 1.1 2.8 3 0 0 3 3 3 0 DDHD domain Glyco_tranf_2_3 PF13641.1 AEO55236.1 - 0.096 12.4 0.0 0.32 10.7 0.0 1.8 2 0 0 2 2 2 0 Glycosyltransferase like family 2 DUF202 PF02656.10 AEO55237.1 - 1.8e-16 60.0 0.7 2.5e-16 59.6 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF202) COX4_pro_2 PF07835.7 AEO55237.1 - 0.074 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial aa3 type cytochrome c oxidase subunit IV RPA_C PF08784.6 AEO55238.1 - 2.2e-21 76.1 0.3 2.2e-21 76.1 0.2 1.9 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 AEO55238.1 - 4.3e-09 36.0 0.1 7.5e-09 35.3 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain S-AdoMet_synt_C PF02773.11 AEO55238.1 - 9 6.0 12.0 0.62 9.7 0.9 3.1 3 0 0 3 3 3 0 S-adenosylmethionine synthetase, C-terminal domain Acetyltransf_7 PF13508.1 AEO55239.1 - 3.3e-09 36.7 0.0 5.9e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 AEO55239.1 - 3.5e-06 26.9 0.0 6.8e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 AEO55239.1 - 0.00011 22.0 0.0 0.00022 21.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 AEO55239.1 - 0.0012 18.8 0.0 0.0022 18.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 AEO55239.1 - 0.012 15.5 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF1517 PF07466.6 AEO55239.1 - 3.1 6.7 5.2 5.4 5.9 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) NUDIX PF00293.23 AEO55241.1 - 7.8e-30 103.2 0.0 1e-29 102.8 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain MatE PF01554.13 AEO55242.1 - 3.9e-57 192.3 25.8 1e-28 99.9 7.3 2.3 2 0 0 2 2 2 2 MatE Npa1 PF11707.3 AEO55243.1 - 1.5e-70 237.8 0.0 8.4e-70 235.3 0.0 2.0 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal Arm PF00514.18 AEO55243.1 - 0.034 13.9 0.1 0.18 11.6 0.0 2.4 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat DNA_mis_repair PF01119.14 AEO55245.1 - 4.7e-34 116.3 0.0 8.7e-34 115.5 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 AEO55245.1 - 6.8e-14 51.6 0.0 1.2e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 AEO55245.1 - 6.5e-12 45.1 0.0 1.4e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Zn_clus PF00172.13 AEO55248.1 - 0.026 14.4 1.2 0.039 13.8 0.9 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Lon_C PF05362.8 AEO55250.1 - 9.6e-68 227.5 0.2 1.8e-67 226.6 0.2 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 AEO55250.1 - 2.9e-24 85.9 0.0 5e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 AEO55250.1 - 1.9e-23 83.1 0.0 7.2e-23 81.2 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 AEO55250.1 - 4.7e-09 36.1 0.0 1.2e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 AEO55250.1 - 2.5e-08 33.4 0.2 7e-08 32.0 0.0 1.9 2 0 0 2 2 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.1 AEO55250.1 - 2e-05 24.6 0.0 8.2e-05 22.6 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.12 AEO55250.1 - 6e-05 22.5 0.0 0.00013 21.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 AEO55250.1 - 8.2e-05 23.4 0.0 0.00028 21.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 AEO55250.1 - 8.5e-05 22.1 0.0 0.00028 20.4 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AEO55250.1 - 0.00033 20.7 0.0 0.0029 17.7 0.0 2.6 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 AEO55250.1 - 0.00076 18.6 0.1 0.0022 17.0 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 AEO55250.1 - 0.00087 19.2 0.0 0.0024 17.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 AEO55250.1 - 0.0011 18.7 0.1 0.0099 15.6 0.0 2.7 3 0 0 3 3 1 1 Part of AAA domain AAA_33 PF13671.1 AEO55250.1 - 0.0018 18.1 0.0 0.0049 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 AEO55250.1 - 0.004 15.9 0.1 0.012 14.3 0.0 1.7 2 0 0 2 2 2 1 TIP49 C-terminus AAA_14 PF13173.1 AEO55250.1 - 0.0041 17.0 0.0 0.009 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 AEO55250.1 - 0.011 15.1 0.0 0.038 13.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 AEO55250.1 - 0.021 14.5 0.0 0.054 13.1 0.0 1.7 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 AEO55250.1 - 0.029 14.5 0.0 0.16 12.1 0.0 2.2 2 0 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.7 AEO55250.1 - 0.03 13.4 0.0 0.059 12.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin UPF0079 PF02367.12 AEO55250.1 - 0.048 13.3 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 AEO55250.1 - 0.052 13.2 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 AEO55250.1 - 0.054 13.8 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_PrkA PF08298.6 AEO55250.1 - 0.058 12.0 0.1 1.2 7.7 0.0 2.2 2 0 0 2 2 2 0 PrkA AAA domain AAA_24 PF13479.1 AEO55250.1 - 0.069 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 AEO55250.1 - 0.11 12.7 2.4 0.21 11.9 0.0 2.3 2 1 0 2 2 1 0 AAA domain Mg_chelatase PF01078.16 AEO55250.1 - 0.11 11.5 0.2 0.25 10.4 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF258 PF03193.11 AEO55250.1 - 0.14 11.3 0.0 0.31 10.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NB-ARC PF00931.17 AEO55250.1 - 0.21 10.4 0.0 0.37 9.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain MOR2-PAG1_N PF14222.1 AEO55251.1 - 1.5e-223 743.5 0.0 2.5e-223 742.7 0.0 1.4 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 AEO55251.1 - 4.5e-96 321.6 0.3 1.2e-95 320.2 0.2 1.8 1 0 0 1 1 1 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 AEO55251.1 - 1.1e-36 125.9 5.6 6.3e-15 53.9 0.0 3.8 2 1 1 3 3 3 3 Cell morphogenesis central region FAD_binding_1 PF00667.15 AEO55252.1 - 1.3e-63 214.3 0.0 1.9e-63 213.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 AEO55252.1 - 2.9e-34 118.1 0.5 6e-34 117.1 0.1 1.8 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.16 AEO55252.1 - 4.1e-21 75.5 0.1 1.2e-20 74.1 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 AEO55252.1 - 0.013 15.5 0.0 0.03 14.3 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin domain RRM_1 PF00076.17 AEO55253.1 - 1.2e-25 88.9 0.0 2.7e-12 46.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO55253.1 - 3.6e-17 62.1 0.0 4e-07 29.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO55253.1 - 9.2e-09 35.0 0.1 0.0015 18.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4586 PF15239.1 AEO55253.1 - 0.058 12.9 0.2 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4586) RIO1 PF01163.17 AEO55254.1 - 7e-42 142.9 0.0 3.1e-41 140.8 0.0 1.9 1 1 0 1 1 1 1 RIO1 family Rio2_N PF09202.6 AEO55254.1 - 4.4e-32 109.9 0.0 9.5e-32 108.9 0.0 1.6 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 AEO55254.1 - 7.3e-08 32.4 2.2 0.00015 21.6 0.3 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 AEO55254.1 - 3.4e-07 29.5 0.1 0.0017 17.4 0.0 2.6 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family Sigma70_ner PF04546.8 AEO55254.1 - 1.3 8.5 7.3 2.2 7.8 5.1 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region PC_rep PF01851.17 AEO55255.1 - 2e-21 74.9 23.7 8.6e-07 28.8 0.0 9.5 10 0 0 10 10 10 4 Proteasome/cyclosome repeat HEAT_2 PF13646.1 AEO55255.1 - 1.6e-08 34.7 0.2 0.0019 18.4 0.0 4.4 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.17 AEO55255.1 - 0.016 15.2 0.0 32 4.9 0.0 4.0 3 0 0 3 3 3 0 HEAT repeat HEAT_EZ PF13513.1 AEO55255.1 - 0.017 15.6 0.3 0.52 10.8 0.0 3.4 2 1 1 3 3 3 0 HEAT-like repeat TPR_5 PF12688.2 AEO55255.1 - 0.024 14.6 0.3 5.4 7.0 0.0 3.3 2 1 1 3 3 3 0 Tetratrico peptide repeat Sec1 PF00995.18 AEO55256.1 - 1.4e-129 433.3 0.0 1.6e-129 433.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family FadA PF09403.5 AEO55256.1 - 0.029 14.3 0.4 0.087 12.8 0.3 1.8 1 0 0 1 1 1 0 Adhesion protein FadA Apo-CIII PF05778.7 AEO55256.1 - 0.072 12.4 0.1 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) RibD_C PF01872.12 AEO55257.1 - 5.4e-32 111.0 0.0 7.2e-32 110.6 0.0 1.2 1 0 0 1 1 1 1 RibD C-terminal domain CYSTM PF12734.2 AEO55258.1 - 1.9e-06 27.7 5.3 1.9e-06 27.7 3.7 4.6 3 1 0 3 3 3 1 Cysteine-rich TM module stress tolerance FAD_binding_3 PF01494.14 AEO55259.1 - 1.1e-08 34.5 0.1 1.1e-07 31.3 0.1 2.0 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 AEO55259.1 - 0.00085 18.2 0.0 0.0015 17.4 0.0 1.4 1 1 0 1 1 1 1 Squalene epoxidase NAD_binding_8 PF13450.1 AEO55260.1 - 1.8e-07 31.0 0.1 2.3e-07 30.7 0.1 1.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 AEO55260.1 - 0.00035 19.5 0.2 0.00043 19.2 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 AEO55260.1 - 0.001 18.1 0.0 0.0011 18.0 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 AEO55260.1 - 0.0012 18.7 0.4 0.0015 18.4 0.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 AEO55260.1 - 0.0013 17.7 0.4 0.0015 17.4 0.3 1.1 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 AEO55260.1 - 0.0039 15.8 0.2 0.0046 15.6 0.1 1.0 1 0 0 1 1 1 1 Tryptophan halogenase Thi4 PF01946.12 AEO55260.1 - 0.0045 16.1 0.1 0.0055 15.8 0.1 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 AEO55260.1 - 0.0065 16.8 0.7 0.0083 16.5 0.5 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 AEO55260.1 - 0.014 15.5 1.0 0.091 12.8 0.7 2.1 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 AEO55260.1 - 0.027 14.2 0.2 0.04 13.7 0.1 1.2 1 0 0 1 1 1 0 ThiF family Pyr_redox_3 PF13738.1 AEO55260.1 - 0.03 14.3 0.1 0.03 14.3 0.1 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 AEO55260.1 - 0.047 12.5 0.7 0.057 12.2 0.5 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 AEO55260.1 - 0.049 13.3 0.2 0.07 12.9 0.1 1.2 1 0 0 1 1 1 0 FAD-NAD(P)-binding 3HCDH_N PF02737.13 AEO55260.1 - 0.099 12.2 0.5 0.13 11.9 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 AEO55260.1 - 0.17 10.3 0.6 0.21 10.0 0.4 1.1 1 0 0 1 1 1 0 HI0933-like protein F420_oxidored PF03807.12 AEO55260.1 - 1.1 9.7 3.2 1.1 9.7 0.9 1.8 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DUF221 PF02714.10 AEO55261.1 - 3.4e-103 344.9 25.8 3.4e-103 344.9 17.9 1.7 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 AEO55261.1 - 5e-37 126.8 0.1 5e-37 126.8 0.1 3.9 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 AEO55261.1 - 2.3e-16 59.4 0.0 5.8e-16 58.1 0.0 1.7 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 AEO55261.1 - 9.2e-09 35.7 4.7 0.0027 18.1 0.7 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF4463) TipAS PF07739.8 AEO55261.1 - 0.07 13.4 3.7 0.068 13.4 0.6 2.3 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain Hamartin PF04388.7 AEO55264.1 - 6.3e-35 121.0 5.3 1.1e-34 120.1 3.6 1.4 1 0 0 1 1 1 1 Hamartin protein Tropomyosin_1 PF12718.2 AEO55264.1 - 0.4 10.5 44.0 0.49 10.2 14.4 2.8 1 1 0 2 2 2 0 Tropomyosin like DUF3584 PF12128.3 AEO55264.1 - 0.53 7.5 38.7 0.8 6.9 26.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) EHN PF06441.7 AEO55264.1 - 0.95 9.4 9.0 0.87 9.5 0.7 2.8 2 0 0 2 2 2 0 Epoxide hydrolase N terminus Prominin PF05478.6 AEO55264.1 - 9.6 3.5 15.1 14 3.0 10.4 1.1 1 0 0 1 1 1 0 Prominin DUF4066 PF13278.1 AEO55265.1 - 3.1e-24 85.0 0.2 2.7e-20 72.2 0.0 2.1 2 0 0 2 2 2 2 Putative amidotransferase DJ-1_PfpI PF01965.19 AEO55265.1 - 7.7e-06 25.4 0.0 2.4e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family Phage_head_fibr PF11133.3 AEO55265.1 - 0.029 13.5 0.0 0.04 13.1 0.0 1.2 1 0 0 1 1 1 0 Head fiber protein Peptidase_S51 PF03575.12 AEO55265.1 - 0.077 12.7 0.1 0.22 11.2 0.0 1.7 2 0 0 2 2 2 0 Peptidase family S51 Ribosomal_L23 PF00276.15 AEO55266.1 - 2.1e-14 53.2 0.0 2.9e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L23 MT-A70 PF05063.9 AEO55267.1 - 4.7e-29 101.1 0.0 7e-29 100.6 0.0 1.3 1 0 0 1 1 1 1 MT-A70 Methyltransf_26 PF13659.1 AEO55267.1 - 0.00046 20.2 0.1 0.00067 19.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF1470 PF07336.6 AEO55267.1 - 0.91 9.8 7.6 2.1 8.6 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1470) Mito_carr PF00153.22 AEO55268.1 - 2.2e-61 203.5 1.8 1.9e-21 75.5 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein 4HBT PF03061.17 AEO55269.1 - 1.6e-11 44.1 0.1 3.1e-11 43.2 0.0 1.5 2 0 0 2 2 2 1 Thioesterase superfamily DUF2956 PF11169.3 AEO55269.1 - 0.031 14.2 0.1 0.052 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) ORC4_C PF14629.1 AEO55270.1 - 4.1e-62 209.2 0.0 6.3e-62 208.5 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 AEO55270.1 - 4.3e-16 59.4 0.2 7.5e-15 55.3 0.2 2.7 1 1 0 1 1 1 1 AAA ATPase domain PHD_2 PF13831.1 AEO55270.1 - 9.9e-13 47.1 2.1 1.8e-12 46.3 1.5 1.5 1 0 0 1 1 1 1 PHD-finger PHD PF00628.24 AEO55270.1 - 4.5e-11 42.2 6.7 7.7e-11 41.5 4.6 1.4 1 0 0 1 1 1 1 PHD-finger NACHT PF05729.7 AEO55270.1 - 5.7e-09 35.8 0.0 1.1e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA PF00004.24 AEO55270.1 - 1.2e-08 35.2 0.0 2.7e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AEO55270.1 - 1.6e-07 31.5 0.0 3.5e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 AEO55270.1 - 2.4e-05 24.1 0.0 4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase KAP_NTPase PF07693.9 AEO55270.1 - 0.00019 20.5 0.0 0.00054 19.0 0.0 1.6 1 1 1 2 2 2 1 KAP family P-loop domain AAA_14 PF13173.1 AEO55270.1 - 0.00051 19.9 0.0 0.0013 18.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.17 AEO55270.1 - 0.0012 17.7 0.1 0.002 17.0 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain DUF815 PF05673.8 AEO55270.1 - 0.0016 17.4 0.0 0.0028 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ATP-synt_ab PF00006.20 AEO55270.1 - 0.0026 17.2 0.0 0.0059 16.1 0.0 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain SMC_N PF02463.14 AEO55270.1 - 0.0027 16.9 0.0 0.0052 16.0 0.0 1.4 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain Prok-RING_1 PF14446.1 AEO55270.1 - 0.0037 16.9 2.6 0.008 15.8 1.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 C1_1 PF00130.17 AEO55270.1 - 0.0037 16.9 0.1 0.0075 15.9 0.1 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) MobB PF03205.9 AEO55270.1 - 0.0046 16.6 0.0 0.013 15.1 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B FYVE_2 PF02318.11 AEO55270.1 - 0.0055 16.5 0.4 0.012 15.5 0.3 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger ABC_tran PF00005.22 AEO55270.1 - 0.0063 16.8 0.1 0.02 15.2 0.0 1.9 2 0 0 2 2 1 1 ABC transporter AAA_17 PF13207.1 AEO55270.1 - 0.0097 16.7 0.2 0.042 14.6 0.0 2.3 2 1 0 2 2 1 1 AAA domain AAA_10 PF12846.2 AEO55270.1 - 0.01 15.2 0.1 0.58 9.5 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain FtsK_SpoIIIE PF01580.13 AEO55270.1 - 0.011 15.1 0.0 0.034 13.6 0.0 1.7 2 0 0 2 2 1 0 FtsK/SpoIIIE family PduV-EutP PF10662.4 AEO55270.1 - 0.018 14.5 0.0 0.055 12.9 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 AEO55270.1 - 0.025 14.7 0.0 0.066 13.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.1 AEO55270.1 - 0.028 13.9 0.0 0.066 12.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 AEO55270.1 - 0.04 13.6 0.0 0.081 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Miro PF08477.8 AEO55270.1 - 0.067 13.6 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein Septin PF00735.13 AEO55270.1 - 0.071 12.1 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Septin Sigma54_activat PF00158.21 AEO55270.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain PIF1 PF05970.9 AEO55270.1 - 0.1 11.5 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase Bac_DnaA PF00308.13 AEO55270.1 - 0.12 11.9 0.0 3.8 7.0 0.0 2.3 2 0 0 2 2 2 0 Bacterial dnaA protein DZR PF12773.2 AEO55270.1 - 2.5 7.9 6.3 11 5.9 4.4 2.0 1 1 0 1 1 1 0 Double zinc ribbon DUF2158 PF09926.4 AEO55271.1 - 0.086 12.2 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized small protein (DUF2158) RGS PF00615.14 AEO55272.1 - 4.6e-38 129.9 1.1 2.6e-37 127.4 0.0 2.5 3 0 0 3 3 3 1 Regulator of G protein signaling domain DEP PF00610.16 AEO55272.1 - 1.5e-22 79.1 0.1 2.3e-19 68.9 0.0 2.6 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) CDC45 PF02724.9 AEO55273.1 - 0.0048 15.0 16.8 0.0053 14.8 11.7 1.1 1 0 0 1 1 1 1 CDC45-like protein Daxx PF03344.10 AEO55273.1 - 0.0063 15.0 19.3 0.0068 14.9 13.4 1.1 1 0 0 1 1 1 1 Daxx Family Nop14 PF04147.7 AEO55273.1 - 0.013 13.4 19.0 0.013 13.4 13.2 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.7 AEO55273.1 - 0.028 12.7 15.5 0.033 12.5 10.7 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BUD22 PF09073.5 AEO55273.1 - 0.13 11.3 14.7 0.14 11.2 10.2 1.1 1 0 0 1 1 1 0 BUD22 Radial_spoke PF04712.7 AEO55273.1 - 0.29 9.8 10.0 0.32 9.6 7.0 1.3 1 0 0 1 1 1 0 Radial spokehead-like protein CDC27 PF09507.5 AEO55273.1 - 0.33 10.1 12.9 0.36 9.9 8.9 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Sporozoite_P67 PF05642.6 AEO55273.1 - 0.4 8.5 6.0 0.45 8.3 4.1 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RRN3 PF05327.6 AEO55273.1 - 0.59 8.1 9.6 0.61 8.1 6.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2722 PF10846.3 AEO55273.1 - 0.59 9.0 9.6 0.74 8.7 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) YqfQ PF14181.1 AEO55273.1 - 0.65 10.0 7.6 0.9 9.5 5.3 1.3 1 0 0 1 1 1 0 YqfQ-like protein Tombus_P33 PF08500.5 AEO55273.1 - 0.83 9.3 3.1 1.9 8.2 2.2 1.6 1 1 0 1 1 1 0 Tombusvirus p33 RNA_polI_A34 PF08208.6 AEO55273.1 - 0.95 9.0 7.5 1.2 8.7 5.2 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 SMN PF06003.7 AEO55273.1 - 1.1 8.3 5.6 1.6 7.7 3.9 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) eIF-3c_N PF05470.7 AEO55273.1 - 1.1 7.2 9.5 1.2 7.0 6.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Tim54 PF11711.3 AEO55273.1 - 1.1 7.7 6.9 1.4 7.3 4.8 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SAPS PF04499.10 AEO55273.1 - 1.2 7.7 5.0 1.2 7.6 3.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein XAP5 PF04921.9 AEO55273.1 - 1.2 8.6 8.7 1.5 8.3 6.1 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator Sigma70_ner PF04546.8 AEO55273.1 - 2.8 7.4 19.9 5.9 6.4 13.8 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region Ycf1 PF05758.7 AEO55273.1 - 3 5.4 6.1 3 5.4 4.2 1.0 1 0 0 1 1 1 0 Ycf1 DUF2457 PF10446.4 AEO55273.1 - 3.3 6.3 29.9 5.1 5.7 20.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Paf1 PF03985.8 AEO55273.1 - 3.3 6.3 22.6 4.8 5.8 15.7 1.2 1 0 0 1 1 1 0 Paf1 DUF1510 PF07423.6 AEO55273.1 - 3.5 6.9 19.2 5.7 6.2 13.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Zip PF02535.17 AEO55273.1 - 3.9 6.4 7.1 5 6.0 4.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter HSP90 PF00183.13 AEO55273.1 - 4.7 5.4 17.7 5.7 5.2 12.3 1.1 1 0 0 1 1 1 0 Hsp90 protein RNA_pol_Rpc4 PF05132.9 AEO55273.1 - 5.8 6.9 9.5 10 6.1 6.6 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 CDC73 PF05179.9 AEO55274.1 - 4.4e-41 141.0 0.0 8.6e-41 140.0 0.0 1.5 1 1 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family Bystin PF05291.6 AEO55275.1 - 2.4e-126 420.7 0.0 3.5e-126 420.2 0.0 1.1 1 0 0 1 1 1 1 Bystin DUF383 PF04063.9 AEO55276.1 - 9.2e-68 227.5 0.0 2.8e-67 226.0 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.8 AEO55276.1 - 2.3e-25 87.8 0.6 7.5e-25 86.2 0.4 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF384) Proteasom_PSMB PF10508.4 AEO55276.1 - 0.047 11.9 0.0 0.11 10.7 0.0 1.7 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit Fungal_trans PF04082.13 AEO55277.1 - 1.1e-26 93.3 0.0 1.7e-26 92.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO55277.1 - 3.1e-09 36.5 9.4 4.9e-09 35.9 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1014 PF06244.7 AEO55280.1 - 5.4e-20 71.8 9.5 5.4e-20 71.8 6.6 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF1014) ARGLU PF15346.1 AEO55280.1 - 1.2 8.9 35.9 0.11 12.3 10.2 2.7 2 1 0 2 2 2 0 Arginine and glutamate-rich 1 UQ_con PF00179.21 AEO55281.1 - 4.5e-09 35.8 0.1 6.7e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme 2OG-FeII_Oxy_2 PF13532.1 AEO55284.1 - 5.4e-28 98.1 0.0 7e-28 97.7 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.7 AEO55284.1 - 3.5e-11 42.8 2.0 7.1e-11 41.8 1.4 1.5 1 0 0 1 1 1 1 GRF zinc finger 2OG-FeII_Oxy PF03171.15 AEO55284.1 - 0.017 15.4 0.0 0.031 14.5 0.0 1.5 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily WD40 PF00400.27 AEO55285.1 - 2.7e-28 96.7 16.1 1.4e-10 40.5 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat DEAD PF00270.24 AEO55286.1 - 4.7e-40 136.8 0.0 1.6e-39 135.0 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO55286.1 - 1.2e-20 73.1 0.2 2.6e-20 72.0 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AEO55286.1 - 0.02 14.7 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CUE PF02845.11 AEO55288.1 - 6.4e-11 41.5 0.0 9.5e-11 40.9 0.0 1.3 1 0 0 1 1 1 1 CUE domain cobW PF02492.14 AEO55289.1 - 8.8e-44 149.0 0.2 1.2e-43 148.5 0.2 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain NOT2_3_5 PF04153.13 AEO55289.1 - 6.6e-32 110.1 0.7 1e-31 109.6 0.5 1.3 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family AAA_23 PF13476.1 AEO55289.1 - 0.0058 16.9 0.1 0.013 15.7 0.1 1.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 AEO55289.1 - 0.038 13.5 0.0 0.094 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 AEO55289.1 - 0.04 13.3 0.6 0.24 10.8 0.5 1.8 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_18 PF13238.1 AEO55289.1 - 0.044 14.0 0.1 0.088 13.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 AEO55289.1 - 0.045 13.7 0.3 0.17 11.8 0.2 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase Miro PF08477.8 AEO55289.1 - 0.058 13.8 0.1 0.7 10.4 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein AAA_19 PF13245.1 AEO55289.1 - 0.068 12.9 0.0 0.2 11.4 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_10 PF12846.2 AEO55289.1 - 0.1 12.0 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain Arch_ATPase PF01637.13 AEO55289.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase Septin PF00735.13 AEO55289.1 - 0.23 10.4 0.5 9.8 5.0 0.1 2.1 2 0 0 2 2 2 0 Septin ATP_bind_1 PF03029.12 AEO55289.1 - 0.3 10.6 0.9 2.4 7.6 0.6 2.1 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein Mob1_phocein PF03637.12 AEO55290.1 - 9.7e-26 90.4 0.3 1.5e-25 89.8 0.2 1.2 1 0 0 1 1 1 1 Mob1/phocein family Fungal_trans_2 PF11951.3 AEO55292.1 - 2.7e-15 55.8 1.7 3e-14 52.4 1.2 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO55292.1 - 4.3e-06 26.5 12.3 7.4e-06 25.7 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ERM PF00769.14 AEO55292.1 - 0.56 9.7 3.0 1.1 8.6 0.0 2.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family MOSC PF03473.12 AEO55293.1 - 6.2e-15 54.8 0.0 1.2e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 AEO55293.1 - 6.8e-12 45.1 0.0 1.4e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain SMC_N PF02463.14 AEO55294.1 - 4.1e-71 238.7 4.8 9.1e-39 132.9 0.0 2.6 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 AEO55294.1 - 1.9e-22 79.4 3.3 5.2e-22 78.0 0.3 3.3 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 AEO55294.1 - 7.3e-14 52.4 0.2 5.4e-06 26.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 AEO55294.1 - 5.9e-13 49.5 18.1 5.9e-13 49.5 12.6 6.7 2 2 3 5 5 5 1 AAA domain AAA_29 PF13555.1 AEO55294.1 - 8.7e-05 21.9 0.0 0.00019 20.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain GAS PF13851.1 AEO55294.1 - 0.0013 17.9 7.2 0.0013 17.9 5.0 8.1 2 2 5 9 9 9 2 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 AEO55294.1 - 0.03 13.5 31.9 0.34 10.0 0.5 6.8 3 2 5 8 8 8 0 Reovirus sigma C capsid protein MscS_porin PF12795.2 AEO55294.1 - 6.7 5.9 115.1 0.034 13.4 29.6 6.4 3 2 2 6 6 6 0 Mechanosensitive ion channel porin domain AAA_15 PF13175.1 AEO55294.1 - 7.3 5.5 26.8 0.26 10.3 7.8 4.4 3 1 0 3 3 3 0 AAA ATPase domain Arv1 PF04161.8 AEO55295.1 - 5.9e-45 153.7 0.0 7.8e-45 153.3 0.0 1.1 1 0 0 1 1 1 1 Arv1-like family LysM PF01476.15 AEO55295.1 - 0.15 11.9 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 LysM domain ATP_synt_H PF05493.8 AEO55296.1 - 6.1e-27 93.4 0.8 6.8e-27 93.3 0.5 1.0 1 0 0 1 1 1 1 ATP synthase subunit H HPP PF04982.8 AEO55296.1 - 0.036 13.9 0.6 0.043 13.6 0.4 1.1 1 0 0 1 1 1 0 HPP family DUF2142 PF09913.4 AEO55296.1 - 0.088 11.4 0.1 0.094 11.3 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) ATPase_gene1 PF09527.5 AEO55296.1 - 5.7 6.8 6.5 1.8 8.4 1.8 2.0 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit (ATPase_gene1) NAD_binding_2 PF03446.10 AEO55297.1 - 1.8e-21 76.6 0.2 2.6e-21 76.1 0.2 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 AEO55297.1 - 5.2e-08 32.9 0.0 8.4e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.15 AEO55297.1 - 0.0054 16.8 0.1 0.0098 15.9 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DUF619 PF04768.8 AEO55298.1 - 7.7e-50 168.6 0.0 6.5e-49 165.6 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF619) BAR_2 PF10455.4 AEO55299.1 - 5.2e-58 196.2 0.0 7.6e-58 195.7 0.0 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 AEO55299.1 - 1.1e-21 77.4 0.2 7.5e-21 74.6 0.2 1.9 1 1 0 1 1 1 1 BAR domain EIF4E-T PF10477.4 AEO55299.1 - 0.0038 16.0 0.6 0.0052 15.6 0.4 1.2 1 0 0 1 1 1 1 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DUF3366 PF11846.3 AEO55299.1 - 0.086 12.7 3.0 0.13 12.0 1.3 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF3366) LSM PF01423.17 AEO55300.1 - 2.9e-16 58.7 0.0 4.8e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 LSM domain GRP PF07172.6 AEO55300.1 - 6.9 7.2 28.1 8.8 6.8 19.5 1.2 1 0 0 1 1 1 0 Glycine rich protein family PPR_3 PF13812.1 AEO55301.1 - 1.5e-15 56.0 1.0 0.0014 18.7 0.0 8.6 10 0 0 10 10 10 3 Pentatricopeptide repeat domain PPR PF01535.15 AEO55301.1 - 2.7e-13 48.9 0.3 0.39 10.8 0.0 7.2 7 0 0 7 7 7 4 PPR repeat PPR_2 PF13041.1 AEO55301.1 - 2.4e-12 46.6 0.0 0.00058 19.7 0.0 7.3 5 2 2 7 7 7 1 PPR repeat family PPR_1 PF12854.2 AEO55301.1 - 3.3e-06 26.4 0.0 0.75 9.3 0.0 5.3 5 0 0 5 5 5 2 PPR repeat TPR_16 PF13432.1 AEO55301.1 - 0.0027 18.3 0.4 0.11 13.1 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 AEO55301.1 - 0.091 12.7 0.1 15 5.7 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 AEO55301.1 - 1.2 9.9 10.4 6.3 7.7 0.0 6.2 8 1 0 8 8 8 0 Tetratricopeptide repeat MFS_1 PF07690.11 AEO55302.1 - 4.5e-29 101.2 29.7 3.3e-21 75.4 9.7 2.4 3 0 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO55302.1 - 3.7e-08 32.3 1.5 3.7e-08 32.3 1.1 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter DUF3278 PF11683.3 AEO55302.1 - 0.056 13.4 4.4 0.56 10.1 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3278) HIT PF01230.18 AEO55303.1 - 9.3e-19 67.7 0.0 2.2e-18 66.6 0.0 1.6 1 1 0 1 1 1 1 HIT domain DcpS_C PF11969.3 AEO55303.1 - 0.0071 16.5 0.0 1.6 8.9 0.0 2.2 2 0 0 2 2 2 2 Scavenger mRNA decapping enzyme C-term binding Mito_fiss_reg PF05308.6 AEO55303.1 - 1.7 7.9 8.8 2.7 7.2 6.1 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Pex14_N PF04695.8 AEO55303.1 - 1.8 8.6 8.8 0.81 9.7 2.0 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF605 PF04652.11 AEO55303.1 - 4 6.7 17.8 0.34 10.2 7.9 2.0 2 0 0 2 2 2 0 Vta1 like TMEM171 PF15471.1 AEO55303.1 - 6.7 5.4 7.9 0.91 8.2 2.9 1.4 2 0 0 2 2 2 0 Transmembrane protein family 171 Totivirus_coat PF05518.6 AEO55303.1 - 7.3 4.2 8.1 11 3.6 5.6 1.2 1 0 0 1 1 1 0 Totivirus coat protein Fungal_trans PF04082.13 AEO55304.1 - 2.4e-44 151.1 0.0 3.6e-44 150.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO55304.1 - 8.4e-09 35.1 6.6 1.8e-08 34.1 4.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ferrochelatase PF00762.14 AEO55305.1 - 6e-93 311.2 0.0 6.9e-93 311.0 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Ku PF02735.11 AEO55306.1 - 1.6e-39 135.3 0.0 3.4e-39 134.3 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 AEO55306.1 - 1.6e-34 119.2 0.0 2.3e-34 118.7 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 AEO55306.1 - 3.2e-16 59.6 0.0 8.6e-16 58.2 0.0 1.8 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.22 AEO55306.1 - 7.4e-12 44.4 0.2 3.2e-11 42.4 0.1 2.0 2 0 0 2 2 2 1 SAP domain HeH PF12949.2 AEO55306.1 - 3.3e-06 26.5 1.1 1e-05 24.9 0.2 2.3 2 1 0 2 2 2 1 HeH/LEM domain VWA_2 PF13519.1 AEO55306.1 - 0.00067 19.8 0.1 0.0012 18.9 0.1 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 AEO55306.1 - 0.0047 16.6 0.0 0.021 14.5 0.0 1.9 1 1 0 1 1 1 1 von Willebrand factor type A domain NOZZLE PF08744.5 AEO55306.1 - 0.24 10.7 0.9 6.1 6.1 0.0 2.1 2 0 0 2 2 2 0 Plant transcription factor NOZZLE Zn_clus PF00172.13 AEO55307.1 - 0.00069 19.4 8.3 0.0012 18.6 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-DHHC PF01529.15 AEO55307.1 - 6 6.2 8.5 3 7.2 1.0 2.6 2 0 0 2 2 2 0 DHHC palmitoyltransferase La PF05383.12 AEO55308.1 - 2.4e-16 59.2 0.0 4e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 La domain RRM_6 PF14259.1 AEO55308.1 - 8.4e-10 38.4 0.0 1.6e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AEO55308.1 - 9.2e-08 31.6 0.1 2e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO55308.1 - 3.2e-05 23.6 0.0 6.6e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) S4 PF01479.20 AEO55309.1 - 5.5e-15 54.5 0.0 9.4e-15 53.7 0.0 1.4 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 AEO55309.1 - 0.011 15.3 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 S4 domain Septin PF00735.13 AEO55310.1 - 2.4e-122 407.3 0.2 2.4e-122 407.3 0.2 1.7 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 AEO55310.1 - 4e-07 29.9 0.0 9.1e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 AEO55310.1 - 8.3e-06 25.3 0.9 0.00038 19.9 0.0 3.0 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 AEO55310.1 - 5.7e-05 22.3 0.3 0.00038 19.6 0.2 2.2 1 1 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 AEO55310.1 - 6.2e-05 23.3 0.6 0.017 15.3 0.0 2.5 2 0 0 2 2 2 1 ABC transporter AAA_10 PF12846.2 AEO55310.1 - 0.00049 19.6 0.6 0.0018 17.7 0.1 2.0 2 1 0 2 2 2 1 AAA-like domain AIG1 PF04548.11 AEO55310.1 - 0.00054 19.1 1.4 0.0013 17.8 0.0 2.1 2 0 0 2 2 2 1 AIG1 family Miro PF08477.8 AEO55310.1 - 0.00079 19.9 0.2 0.0032 17.9 0.0 2.1 2 0 0 2 2 1 1 Miro-like protein AAA_16 PF13191.1 AEO55310.1 - 0.0015 18.5 0.2 0.013 15.4 0.0 2.4 3 0 0 3 3 3 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 AEO55310.1 - 0.0037 16.7 0.0 0.02 14.3 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family Ras PF00071.17 AEO55310.1 - 0.0051 16.2 0.2 0.028 13.8 0.0 2.3 3 0 0 3 3 3 1 Ras family AAA_22 PF13401.1 AEO55310.1 - 0.0053 16.9 0.0 0.025 14.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 AEO55310.1 - 0.0067 15.9 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATP_bind_1 PF03029.12 AEO55310.1 - 0.026 14.0 0.5 4.1 6.8 0.0 3.0 1 1 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_32 PF13654.1 AEO55310.1 - 0.038 12.6 8.7 0.36 9.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 AEO55310.1 - 0.05 13.4 8.1 0.56 9.9 0.1 3.6 3 2 1 4 4 4 0 Dynamin family Exonuc_VII_L PF02601.10 AEO55310.1 - 0.067 12.3 6.8 0.13 11.3 4.7 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit MobB PF03205.9 AEO55310.1 - 0.069 12.8 1.8 0.22 11.2 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 AEO55310.1 - 0.078 12.3 0.0 0.25 10.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 AEO55310.1 - 0.083 13.0 1.0 0.36 11.0 0.0 2.4 3 0 0 3 3 2 0 RNA helicase AAA_24 PF13479.1 AEO55310.1 - 0.087 12.3 0.5 0.16 11.5 0.0 1.7 2 0 0 2 2 1 0 AAA domain Strep_SA_rep PF06696.6 AEO55310.1 - 0.4 10.5 0.1 0.4 10.5 0.1 2.3 2 0 0 2 2 2 0 Streptococcal surface antigen repeat YlqD PF11068.3 AEO55310.1 - 0.6 10.1 10.5 1.2 9.2 7.3 1.5 1 0 0 1 1 1 0 YlqD protein Phage_GPO PF05929.6 AEO55310.1 - 0.77 8.9 5.9 1.3 8.1 4.1 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF2937 PF11157.3 AEO55310.1 - 1.5 8.1 3.5 2.8 7.2 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) IncA PF04156.9 AEO55310.1 - 2.3 7.7 8.8 3.6 7.1 6.1 1.3 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 AEO55310.1 - 2.4 5.9 8.8 4.1 5.1 6.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF87 PF01935.12 AEO55310.1 - 2.6 7.8 0.0 2.6 7.8 0.0 2.5 3 0 0 3 3 2 0 Domain of unknown function DUF87 PLA2_B PF01735.13 AEO55311.1 - 2.5e-26 91.9 0.0 4.9e-26 90.9 0.0 1.4 1 1 0 1 1 1 1 Lysophospholipase catalytic domain Ribonuclease_3 PF00636.21 AEO55312.1 - 1.8e-08 34.8 0.0 4e-08 33.6 0.0 1.6 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 AEO55312.1 - 3.8e-08 33.3 0.0 0.0013 18.7 0.0 2.2 2 0 0 2 2 2 2 Ribonuclease-III-like dsrm PF00035.20 AEO55312.1 - 0.00039 20.9 0.0 0.00082 19.9 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif bZIP_1 PF00170.16 AEO55314.1 - 1 9.3 16.3 0.14 12.1 6.4 2.2 1 1 1 2 2 2 0 bZIP transcription factor Metallophos PF00149.23 AEO55315.1 - 5.7e-36 123.7 0.4 3.5e-29 101.6 0.1 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase GSK-3_bind PF05350.7 AEO55315.1 - 0.3 10.4 2.7 0.54 9.6 1.9 1.3 1 0 0 1 1 1 0 Glycogen synthase kinase-3 binding Cyclin_N PF00134.18 AEO55316.1 - 0.1 12.1 0.0 0.61 9.6 0.0 1.9 2 0 0 2 2 2 0 Cyclin, N-terminal domain FBA_2 PF07735.12 AEO55317.1 - 3.7 7.4 8.4 0.22 11.3 1.8 1.9 2 1 0 2 2 2 0 F-box associated CPSase_L_D2 PF02786.12 AEO55319.1 - 3.6e-114 379.3 0.2 2.6e-84 281.7 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain GATase PF00117.23 AEO55319.1 - 1.6e-43 148.4 0.0 3.6e-43 147.2 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 AEO55319.1 - 7.9e-43 145.0 0.0 1.8e-42 143.9 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.16 AEO55319.1 - 7.2e-42 142.4 0.0 1.5e-41 141.3 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_chain PF00289.17 AEO55319.1 - 2.8e-41 140.0 0.0 3.6e-20 72.0 0.0 2.9 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain CPSase_L_D3 PF02787.14 AEO55319.1 - 3.6e-41 139.7 0.0 1.2e-40 138.1 0.0 2.0 2 0 0 2 2 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 AEO55319.1 - 1.8e-37 128.8 0.3 1.2e-23 83.8 0.0 2.8 3 0 0 3 3 3 2 ATP-grasp domain OTCace PF00185.19 AEO55319.1 - 5.2e-33 114.1 0.0 1.1e-32 113.0 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATPgrasp_Ter PF15632.1 AEO55319.1 - 6.2e-23 81.0 0.1 2.1e-12 46.4 0.0 3.9 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.17 AEO55319.1 - 4.6e-21 74.5 0.0 2.3e-20 72.3 0.0 2.3 1 0 0 1 1 1 1 MGS-like domain ATP-grasp PF02222.17 AEO55319.1 - 1.4e-17 63.5 0.1 5.2e-09 35.6 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 AEO55319.1 - 1.3e-16 60.6 0.7 3.7e-08 33.0 0.1 2.7 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 AEO55319.1 - 4.3e-07 29.9 0.4 0.0037 17.1 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 AEO55319.1 - 9.7e-07 28.4 0.7 3.5e-05 23.3 0.5 2.5 1 1 0 1 1 1 1 Peptidase C26 GARS_A PF01071.14 AEO55319.1 - 0.00018 21.1 0.1 0.57 9.7 0.0 2.8 2 1 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DJ-1_PfpI PF01965.19 AEO55319.1 - 0.012 15.0 0.0 0.029 13.8 0.0 1.6 1 0 0 1 1 1 0 DJ-1/PfpI family DUF992 PF06186.6 AEO55319.1 - 0.086 12.1 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF992) Ion_trans PF00520.26 AEO55320.1 - 6.5e-05 22.2 9.9 6.5e-05 22.2 6.8 1.6 1 1 0 1 1 1 1 Ion transport protein PKD_channel PF08016.7 AEO55320.1 - 0.0065 14.9 3.0 0.0065 14.9 2.1 2.4 2 1 1 3 3 3 2 Polycystin cation channel BAF1_ABF1 PF04684.8 AEO55321.1 - 0.0029 16.5 18.4 0.0029 16.5 12.8 2.1 2 0 0 2 2 2 1 BAF1 / ABF1 chromatin reorganising factor Zip PF02535.17 AEO55321.1 - 0.0045 16.0 10.1 0.0073 15.3 7.0 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Macoilin PF09726.4 AEO55321.1 - 0.037 12.3 0.8 0.057 11.7 0.6 1.3 1 0 0 1 1 1 0 Transmembrane protein SelP_N PF04592.9 AEO55321.1 - 1.7 7.9 14.0 3 7.1 9.7 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region TAP42 PF04177.7 AEO55324.1 - 5.2e-105 351.1 0.0 5.9e-105 350.9 0.0 1.0 1 0 0 1 1 1 1 TAP42-like family PNPOx_C PF10590.4 AEO55325.1 - 3e-21 74.6 3.3 2.1e-20 71.9 2.9 2.0 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 AEO55325.1 - 1e-11 44.6 0.0 6.4e-11 42.1 0.0 2.0 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.2 AEO55325.1 - 0.14 12.4 0.0 0.27 11.5 0.0 1.6 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Ribonuclease_3 PF00636.21 AEO55326.1 - 5.5e-42 142.8 0.0 5.3e-20 71.9 0.0 3.1 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 AEO55326.1 - 1.4e-22 79.9 0.0 3.8e-09 36.5 0.0 3.6 3 0 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.9 AEO55326.1 - 1.5e-21 75.9 0.2 9.6e-20 70.1 0.0 3.3 3 0 0 3 3 3 1 Dicer dimerisation domain Helicase_C PF00271.26 AEO55326.1 - 6.4e-15 54.7 0.0 1.5e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AEO55326.1 - 8.8e-12 45.2 0.0 1.9e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 AEO55326.1 - 1.9e-10 40.4 0.0 3.3e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase dsrm PF00035.20 AEO55326.1 - 0.00022 21.7 0.2 0.87 10.2 0.1 3.1 3 0 0 3 3 3 2 Double-stranded RNA binding motif AAA_22 PF13401.1 AEO55326.1 - 0.016 15.3 0.0 0.052 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain Dus PF01207.12 AEO55326.1 - 0.1 11.4 0.0 0.23 10.2 0.0 1.5 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) Peptidase_C12 PF01088.16 AEO55328.1 - 2.7e-61 206.4 0.0 3.2e-61 206.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 SUV3_C PF12513.3 AEO55329.1 - 9.9e-17 60.1 0.5 2.2e-16 59.0 0.4 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 AEO55329.1 - 1.4e-08 34.5 0.0 2.7e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TK PF00265.13 AEO55329.1 - 0.034 13.7 0.0 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 Thymidine kinase Synaptobrevin PF00957.16 AEO55330.1 - 9.6e-31 105.2 0.0 1.3e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 AEO55330.1 - 2.3e-19 68.7 0.0 3.5e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain adh_short PF00106.20 AEO55332.1 - 1.3e-14 54.5 0.8 7.1e-14 52.0 0.6 2.2 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO55332.1 - 1.6e-09 37.7 1.5 1.6e-09 37.6 0.1 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 AEO55332.1 - 1.9e-05 24.2 0.0 3.5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ApbA PF02558.11 AEO55332.1 - 0.00059 19.3 0.4 0.036 13.5 0.0 2.5 3 0 0 3 3 3 1 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.1 AEO55332.1 - 0.00083 19.4 0.1 0.002 18.1 0.1 1.7 1 0 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 AEO55332.1 - 0.0042 16.8 0.0 0.011 15.5 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase DAO PF01266.19 AEO55332.1 - 0.02 13.8 0.0 0.057 12.3 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase NdhL PF10716.4 AEO55332.1 - 0.038 13.7 0.6 0.078 12.7 0.4 1.5 1 0 0 1 1 1 0 NADH dehydrogenase transmembrane subunit Glyco_trans_4_4 PF13579.1 AEO55332.1 - 0.042 13.9 4.0 0.047 13.8 2.2 1.7 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain E1-N PF14463.1 AEO55332.1 - 0.058 13.0 0.2 0.11 12.0 0.1 1.6 1 1 0 1 1 1 0 E1 N-terminal domain YjeF_N PF03853.10 AEO55332.1 - 0.13 11.8 0.3 0.36 10.4 0.0 1.8 2 0 0 2 2 2 0 YjeF-related protein N-terminus FAD_oxidored PF12831.2 AEO55332.1 - 0.34 9.9 3.2 0.21 10.6 0.9 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase G-patch PF01585.18 AEO55333.1 - 6.7e-09 35.4 0.2 1.2e-08 34.6 0.1 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 AEO55333.1 - 0.016 15.0 1.3 0.19 11.6 0.0 2.9 3 0 0 3 3 3 0 DExH-box splicing factor binding site GAGA PF09237.6 AEO55333.1 - 0.096 12.2 0.8 0.21 11.2 0.6 1.5 1 0 0 1 1 1 0 GAGA factor TFIIF_alpha PF05793.7 AEO55333.1 - 4.8 5.4 12.3 0.3 9.4 1.6 2.1 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Sec63 PF02889.11 AEO55334.1 - 1.7e-145 484.1 0.0 2.1e-97 326.1 0.1 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 AEO55334.1 - 3.2e-52 176.4 0.1 3.3e-28 98.3 0.2 3.3 4 0 0 4 4 4 2 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO55334.1 - 7.9e-16 57.6 0.0 1e-06 28.4 0.0 2.9 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.10 AEO55334.1 - 5.6e-15 55.6 0.0 4e-06 26.8 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 AEO55334.1 - 6.9e-08 32.7 0.0 0.033 14.3 0.0 3.5 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 AEO55334.1 - 4.2e-07 29.6 0.3 0.025 14.3 0.0 3.5 3 0 0 3 3 3 2 Part of AAA domain SNF2_N PF00176.18 AEO55334.1 - 6.5e-06 25.1 0.1 0.042 12.6 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain AAA PF00004.24 AEO55334.1 - 4.2e-05 23.7 0.0 0.85 9.8 0.0 4.4 4 1 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 AEO55334.1 - 0.00016 21.2 0.0 0.094 12.2 0.1 2.6 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 AEO55334.1 - 0.021 13.9 0.0 1.4 8.0 0.0 3.1 3 0 0 3 3 3 0 Zeta toxin IstB_IS21 PF01695.12 AEO55334.1 - 0.023 14.1 0.1 17 4.7 0.0 3.9 4 0 0 4 4 4 0 IstB-like ATP binding protein Ras PF00071.17 AEO55335.1 - 5.1e-65 217.7 0.0 6.2e-65 217.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AEO55335.1 - 1.4e-19 70.7 0.0 2e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AEO55335.1 - 3.8e-13 49.0 0.0 4.2e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 AEO55335.1 - 2e-06 27.3 0.0 3.6e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 AEO55335.1 - 8.4e-06 25.0 0.0 9.1e-06 24.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 AEO55335.1 - 0.004 17.1 0.0 0.0058 16.5 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AEO55335.1 - 0.017 14.4 0.0 0.081 12.1 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF258 PF03193.11 AEO55335.1 - 0.024 13.8 0.0 0.071 12.2 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 SRPRB PF09439.5 AEO55335.1 - 0.027 13.7 0.0 0.032 13.4 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.1 AEO55335.1 - 0.1 12.1 0.0 0.28 10.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 AEO55335.1 - 0.11 12.5 0.0 0.22 11.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.15 AEO55335.1 - 0.12 11.0 0.3 13 4.3 0.0 2.7 1 1 1 2 2 2 0 G-protein alpha subunit NCA2 PF08637.5 AEO55336.1 - 5.1e-89 297.9 0.1 8.8e-89 297.2 0.1 1.3 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 FA_hydroxylase PF04116.8 AEO55337.1 - 1.2e-15 57.8 17.2 1.2e-15 57.8 11.9 2.3 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Pterin_4a PF01329.14 AEO55338.1 - 7.5e-16 57.6 0.0 9e-16 57.4 0.0 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Secretin_N_2 PF07655.8 AEO55338.1 - 0.011 16.0 7.5 0.014 15.7 5.2 1.2 1 0 0 1 1 1 0 Secretin N-terminal domain Pex14_N PF04695.8 AEO55338.1 - 0.039 14.0 0.5 0.039 14.0 0.3 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region bZIP_1 PF00170.16 AEO55339.1 - 1.8e-07 31.0 11.0 4e-06 26.6 7.6 2.1 1 1 0 1 1 1 1 bZIP transcription factor HOASN PF14515.1 AEO55339.1 - 0.02 15.2 0.0 0.045 14.1 0.0 1.5 1 0 0 1 1 1 0 Haem-oxygenase-associated N-terminal helices bZIP_2 PF07716.10 AEO55339.1 - 0.11 12.3 11.1 2.8 7.8 4.4 2.3 1 1 1 2 2 2 0 Basic region leucine zipper Adeno_PIX PF03955.9 AEO55339.1 - 0.12 12.8 2.1 0.17 12.4 0.1 2.1 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) dsrm PF00035.20 AEO55339.1 - 0.21 12.1 1.2 0.29 11.7 0.1 1.8 2 0 0 2 2 2 0 Double-stranded RNA binding motif DUF501 PF04417.7 AEO55339.1 - 0.27 11.0 2.6 0.12 12.1 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF501) Actin PF00022.14 AEO55340.1 - 1.2e-42 145.7 0.0 2.5e-22 78.8 0.0 2.2 2 0 0 2 2 2 2 Actin FUSC-like PF12805.2 AEO55340.1 - 0.057 12.3 0.9 0.13 11.1 0.6 1.5 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS DASH_Dad4 PF08650.5 AEO55342.1 - 1.4e-29 101.8 6.8 1.5e-29 101.7 4.7 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 DASH_Dad1 PF08649.5 AEO55342.1 - 0.11 12.1 3.8 0.14 11.8 2.7 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad1 YL1_C PF08265.6 AEO55343.1 - 2.4e-16 58.9 0.0 3.7e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain DUF3580 PF12117.3 AEO55343.1 - 0.086 12.8 2.9 0.081 12.8 1.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3580) Got1 PF04178.7 AEO55345.1 - 6e-19 68.2 10.2 6.9e-19 68.1 7.1 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family YrhK PF14145.1 AEO55345.1 - 1.2 8.8 7.4 0.33 10.6 2.6 1.9 2 0 0 2 2 2 0 YrhK-like protein Profilin PF00235.14 AEO55346.1 - 6.4e-39 132.8 0.2 7.2e-39 132.6 0.1 1.0 1 0 0 1 1 1 1 Profilin AAA PF00004.24 AEO55349.1 - 6.5e-52 175.2 0.0 2.5e-37 128.0 0.0 3.5 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 AEO55349.1 - 6.5e-08 32.7 2.7 0.00016 21.6 1.1 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA_28 PF13521.1 AEO55349.1 - 5.5e-06 26.4 0.0 0.00059 19.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 AEO55349.1 - 2.2e-05 23.9 4.2 0.4 10.0 0.0 3.7 2 2 1 3 3 3 2 AAA domain AAA_5 PF07728.9 AEO55349.1 - 8.5e-05 22.2 0.1 0.15 11.7 0.0 3.2 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 AEO55349.1 - 0.00011 21.8 0.8 0.2 11.4 0.0 4.1 3 1 0 3 3 3 1 Part of AAA domain RuvB_N PF05496.7 AEO55349.1 - 0.00034 19.7 0.0 0.037 13.0 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 AEO55349.1 - 0.00039 20.3 0.0 0.6 10.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 AEO55349.1 - 0.00041 20.4 8.5 1.4 9.0 0.2 4.8 3 2 2 5 5 5 1 AAA domain NACHT PF05729.7 AEO55349.1 - 0.00077 19.1 4.0 0.17 11.5 2.6 3.5 3 1 0 3 3 3 1 NACHT domain RNA_helicase PF00910.17 AEO55349.1 - 0.002 18.2 0.0 2.7 8.2 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AFG1_ATPase PF03969.11 AEO55349.1 - 0.0025 16.6 0.0 0.016 14.0 0.0 2.2 3 0 0 3 3 3 1 AFG1-like ATPase AAA_2 PF07724.9 AEO55349.1 - 0.0048 16.8 0.0 0.088 12.7 0.0 2.8 3 1 0 3 3 3 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 AEO55349.1 - 0.0081 15.5 0.0 4.1 6.7 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein Vps4_C PF09336.5 AEO55349.1 - 0.0084 15.9 0.0 0.19 11.6 0.0 2.9 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Mg_chelatase PF01078.16 AEO55349.1 - 0.038 13.1 1.1 0.7 9.0 0.1 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 AEO55349.1 - 0.045 14.5 0.1 4.7 8.0 0.0 3.1 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.1 AEO55349.1 - 0.051 13.4 0.0 3.1 7.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.6 AEO55349.1 - 0.055 13.0 0.0 11 5.6 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 AEO55349.1 - 0.055 12.5 0.1 0.75 8.8 0.0 2.4 2 0 0 2 2 2 0 KaiC AAA_18 PF13238.1 AEO55349.1 - 0.06 13.6 0.0 0.17 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 AEO55349.1 - 0.073 13.1 0.0 8.4 6.4 0.0 2.7 2 1 0 2 2 2 0 Sigma-54 interaction domain TIP49 PF06068.8 AEO55349.1 - 0.096 11.3 0.0 2.7 6.6 0.0 2.1 2 0 0 2 2 2 0 TIP49 C-terminus DAP3 PF10236.4 AEO55349.1 - 0.12 11.2 0.1 1.8 7.3 0.0 2.5 2 1 1 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 Bac_DnaA PF00308.13 AEO55349.1 - 0.16 11.6 0.8 0.63 9.6 0.5 2.1 2 1 0 2 2 1 0 Bacterial dnaA protein ABC_tran PF00005.22 AEO55349.1 - 0.2 11.9 0.0 0.6 10.3 0.0 1.8 2 0 0 2 2 1 0 ABC transporter Rad17 PF03215.10 AEO55349.1 - 0.38 9.3 0.0 0.56 8.8 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein SMK-1 PF04802.10 AEO55350.1 - 1.5e-77 259.5 0.2 1.5e-77 259.5 0.1 1.8 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 Glycos_transf_2 PF00535.21 AEO55352.1 - 7e-22 77.9 0.1 1.5e-17 63.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 AEO55352.1 - 5.2e-10 39.5 1.4 3e-07 30.4 0.1 2.6 2 1 1 3 3 3 2 Glycosyltransferase like family 2 SE PF08491.5 AEO55353.1 - 4.1e-84 281.6 0.0 5.6e-84 281.2 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 AEO55353.1 - 1.2e-10 41.0 2.8 7.3e-09 35.1 1.9 2.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 AEO55353.1 - 1.5e-09 37.2 2.3 2.5e-08 33.2 0.5 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 AEO55353.1 - 2.7e-06 26.5 0.6 0.028 13.3 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein GIDA PF01134.17 AEO55353.1 - 1.4e-05 24.1 0.1 0.00092 18.1 0.2 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 AEO55353.1 - 6e-05 22.9 0.2 0.00016 21.6 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 AEO55353.1 - 0.00012 21.3 0.0 0.0002 20.5 0.0 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 AEO55353.1 - 0.0004 19.3 0.4 0.0004 19.3 0.3 1.8 2 0 0 2 2 2 1 FAD binding domain 3HCDH_N PF02737.13 AEO55353.1 - 0.00087 18.9 0.1 0.0016 18.0 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 AEO55353.1 - 0.00091 18.4 0.3 0.0016 17.6 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 AEO55353.1 - 0.0015 18.8 0.9 0.0026 18.1 0.2 1.7 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 AEO55353.1 - 0.0016 17.9 0.1 0.0026 17.2 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 AEO55353.1 - 0.0018 18.4 0.0 0.0029 17.7 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.9 AEO55353.1 - 0.0019 18.1 0.3 0.0041 17.0 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 AEO55353.1 - 0.005 16.5 0.1 0.0086 15.8 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ThiF PF00899.16 AEO55353.1 - 0.07 12.9 0.5 0.13 12.1 0.3 1.4 1 0 0 1 1 1 0 ThiF family HI0933_like PF03486.9 AEO55353.1 - 0.13 10.7 0.1 0.18 10.2 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein HATPase_c_2 PF13581.1 AEO55354.1 - 0.065 13.0 0.4 0.17 11.6 0.3 1.7 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain TPR_14 PF13428.1 AEO55354.1 - 0.22 12.2 34.0 0.74 10.6 0.0 9.3 9 1 2 11 11 11 0 Tetratricopeptide repeat Mito_carr PF00153.22 AEO55355.1 - 8.7e-64 211.2 0.0 5.8e-20 70.8 0.0 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein Peptidase_S24 PF00717.18 AEO55356.1 - 3e-07 29.9 0.2 1e-06 28.2 0.1 1.8 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 AEO55356.1 - 0.00012 21.5 0.0 0.0025 17.3 0.0 2.3 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 EIF_2_alpha PF07541.7 AEO55357.1 - 1.9e-37 127.4 0.0 3.9e-37 126.4 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 AEO55357.1 - 3.1e-13 49.6 0.7 5.2e-13 48.8 0.5 1.4 1 0 0 1 1 1 1 S1 RNA binding domain cNMP_binding PF00027.24 AEO55358.1 - 1e-36 124.6 0.8 8e-18 64.0 0.0 4.9 5 0 0 5 5 5 3 Cyclic nucleotide-binding domain Patatin PF01734.17 AEO55358.1 - 2.8e-19 69.8 2.6 1.4e-18 67.5 1.8 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase DUF1625 PF07787.7 AEO55358.1 - 6.3 5.9 9.0 11 5.1 6.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1625) Pyridoxal_deC PF00282.14 AEO55359.1 - 1.5e-112 375.7 0.0 1.9e-112 375.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Anoctamin PF04547.7 AEO55360.1 - 2.2e-123 412.2 1.5 2.8e-123 411.9 1.1 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel FMN_dh PF01070.13 AEO55361.1 - 8.6e-121 403.1 0.6 1.1e-120 402.7 0.4 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 AEO55361.1 - 6.7e-24 83.4 0.0 1.6e-23 82.3 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 AEO55361.1 - 3.4e-07 29.5 0.1 5.5e-07 28.8 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 AEO55361.1 - 9.5e-05 21.6 0.1 0.00015 21.0 0.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 AEO55361.1 - 0.00033 19.6 0.3 0.00084 18.3 0.2 1.7 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 AEO55361.1 - 0.0025 17.1 0.5 0.24 10.6 0.0 2.3 1 1 0 2 2 2 1 Histidine biosynthesis protein DUF561 PF04481.7 AEO55361.1 - 0.18 10.7 0.0 4 6.3 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF561) Ras PF00071.17 AEO55362.1 - 2.7e-39 134.1 0.0 3.9e-37 127.1 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 AEO55362.1 - 3.6e-18 66.1 0.0 4.7e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AEO55362.1 - 8.8e-10 38.0 0.0 1.3e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 AEO55362.1 - 0.025 14.5 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.5 AEO55362.1 - 0.035 13.3 0.0 0.048 12.8 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 AEO55362.1 - 0.041 13.0 0.0 0.053 12.6 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_33 PF13671.1 AEO55362.1 - 0.045 13.6 0.0 0.07 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF2411 PF10304.4 AEO55362.1 - 0.092 12.3 0.3 0.16 11.5 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2411) AAA_28 PF13521.1 AEO55362.1 - 0.12 12.3 1.0 0.56 10.1 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.1 AEO55362.1 - 0.16 11.5 0.1 0.26 10.8 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 AEO55362.1 - 0.18 11.5 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Arabinose_bd PF12625.2 AEO55364.1 - 0.0048 16.7 0.1 0.0094 15.7 0.1 1.5 1 0 0 1 1 1 1 Arabinose-binding domain of AraC transcription regulator, N-term Glyco_hydro_11 PF00457.12 AEO55365.1 - 1.6e-75 252.5 21.9 1.9e-75 252.2 15.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Homeobox_KN PF05920.6 AEO55367.1 - 3.4e-14 52.2 0.7 1e-13 50.7 0.5 1.9 1 0 0 1 1 1 1 Homeobox KN domain HTH_Tnp_Tc5 PF03221.11 AEO55367.1 - 1.3e-12 47.3 2.8 0.00014 21.6 0.0 5.6 5 1 0 5 5 5 2 Tc5 transposase DNA-binding domain Homeobox PF00046.24 AEO55367.1 - 4.4e-06 26.2 1.1 1.1e-05 24.9 0.8 1.7 1 0 0 1 1 1 1 Homeobox domain zf-C2H2_4 PF13894.1 AEO55367.1 - 0.00063 19.8 19.4 0.0024 18.0 2.3 4.4 3 1 0 3 3 3 1 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AEO55367.1 - 0.041 14.1 5.5 1 9.7 0.6 3.8 3 0 0 3 3 3 0 Zinc-finger double domain Arm_2 PF04826.8 AEO55367.1 - 0.055 12.5 0.0 0.086 11.9 0.0 1.2 1 0 0 1 1 1 0 Armadillo-like zf-C2H2 PF00096.21 AEO55367.1 - 0.11 12.9 18.6 0.11 12.8 2.1 4.2 4 0 0 4 4 4 0 Zinc finger, C2H2 type TF_Zn_Ribbon PF08271.7 AEO55367.1 - 2 7.7 9.1 2.2 7.6 1.3 3.1 3 0 0 3 3 3 0 TFIIB zinc-binding Nipped-B_C PF12830.2 AEO55368.1 - 3e-47 160.6 4.2 7.4e-47 159.4 0.5 3.1 3 1 0 3 3 3 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 AEO55368.1 - 3e-11 42.9 9.0 6.6e-11 41.9 0.6 4.2 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.17 AEO55368.1 - 5.9e-09 35.2 0.7 0.22 11.6 0.0 5.3 4 0 0 4 4 4 3 HEAT repeat Cnd1 PF12717.2 AEO55368.1 - 6.2e-05 22.9 1.7 0.05 13.4 0.0 4.3 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 AEO55368.1 - 6.6e-05 21.4 0.6 0.0015 16.9 0.0 3.3 2 1 1 3 3 3 2 Adaptin N terminal region YL1 PF05764.8 AEO55368.1 - 0.01 15.4 0.9 0.033 13.7 0.6 1.9 1 0 0 1 1 1 0 YL1 nuclear protein TFIIS_C PF01096.13 AEO55370.1 - 1.6e-13 50.0 1.1 1.6e-13 50.0 0.8 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 AEO55370.1 - 1.2e-07 31.2 2.9 1.2e-07 31.2 2.0 2.5 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit DZR PF12773.2 AEO55370.1 - 0.00028 20.6 3.3 0.033 13.9 0.8 2.4 2 0 0 2 2 2 1 Double zinc ribbon C1_1 PF00130.17 AEO55370.1 - 0.0087 15.7 5.7 0.014 15.0 0.8 2.3 2 1 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Rubredoxin PF00301.15 AEO55370.1 - 0.011 15.5 3.6 11 6.0 0.0 3.3 2 1 1 3 3 3 0 Rubredoxin zf-ribbon_3 PF13248.1 AEO55370.1 - 0.023 13.9 9.5 1.2 8.4 0.2 3.6 4 0 0 4 4 4 0 zinc-ribbon domain IBR PF01485.16 AEO55370.1 - 0.03 14.1 6.9 0.47 10.3 0.7 2.3 2 0 0 2 2 2 0 IBR domain tRNA-synt_1f PF01921.13 AEO55370.1 - 0.058 12.0 0.2 0.081 11.5 0.1 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (K) Zn-ribbon_8 PF09723.5 AEO55370.1 - 0.13 12.2 0.1 0.13 12.2 0.1 3.6 3 1 0 3 3 3 0 Zinc ribbon domain zinc_ribbon_2 PF13240.1 AEO55370.1 - 0.37 10.3 18.7 0.79 9.2 0.4 3.6 4 0 0 4 4 3 0 zinc-ribbon domain TerY-C PF15616.1 AEO55370.1 - 0.5 10.3 5.3 0.62 10.0 0.1 2.2 2 0 0 2 2 2 0 TerY-C metal binding domain HypA PF01155.14 AEO55370.1 - 0.52 10.0 9.7 1.3 8.7 1.0 2.2 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-ISL3 PF14690.1 AEO55370.1 - 0.76 9.8 0.1 0.76 9.8 0.1 3.0 2 1 1 3 3 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-H2C2_2 PF13465.1 AEO55370.1 - 0.78 10.1 0.0 0.78 10.1 0.0 3.0 4 0 0 4 4 3 0 Zinc-finger double domain Lar_restr_allev PF14354.1 AEO55370.1 - 0.8 10.0 11.7 2.1 8.6 0.8 3.1 1 1 1 3 3 3 0 Restriction alleviation protein Lar OrfB_Zn_ribbon PF07282.6 AEO55370.1 - 0.9 9.2 11.7 1.2 8.8 1.0 2.5 2 1 0 2 2 2 0 Putative transposase DNA-binding domain zf-C2H2_4 PF13894.1 AEO55370.1 - 0.91 10.0 0.1 0.91 10.0 0.1 2.7 3 0 0 3 3 2 0 C2H2-type zinc finger zinc_ribbon_4 PF13717.1 AEO55370.1 - 0.94 9.2 5.1 9.1 6.0 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain DUF2082 PF09855.4 AEO55370.1 - 1 9.2 0.1 1 9.2 0.1 2.7 3 0 0 3 3 3 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) NOB1_Zn_bind PF08772.6 AEO55370.1 - 1.4 8.8 5.2 14 5.5 0.1 2.9 3 0 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like zinc_ribbon_5 PF13719.1 AEO55370.1 - 1.6 8.3 5.5 7.5 6.2 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain zf-C2H2 PF00096.21 AEO55370.1 - 1.7 9.1 0.1 1.7 9.1 0.1 3.7 4 0 0 4 4 4 0 Zinc finger, C2H2 type Nudix_N_2 PF14803.1 AEO55370.1 - 2.7 7.7 7.2 19 5.0 0.0 3.4 3 0 0 3 3 3 0 Nudix N-terminal Zn_ribbon_recom PF13408.1 AEO55370.1 - 3.4 7.9 13.8 6.3 7.1 0.1 3.2 2 1 1 3 3 3 0 Recombinase zinc beta ribbon domain HEAT_2 PF13646.1 AEO55371.1 - 2.3e-33 114.3 5.4 3.8e-16 59.1 0.2 3.8 2 2 2 4 4 4 3 HEAT repeats HEAT_PBS PF03130.11 AEO55371.1 - 5.9e-21 72.7 6.9 0.005 17.1 0.0 6.6 7 0 0 7 7 7 5 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 AEO55371.1 - 1.3e-10 41.3 7.0 0.00076 19.8 0.0 4.9 3 2 1 4 4 4 3 HEAT-like repeat HEAT PF02985.17 AEO55371.1 - 2.9e-08 33.1 4.6 1.2 9.4 0.0 6.1 7 0 0 7 7 7 3 HEAT repeat Cohesin_HEAT PF12765.2 AEO55371.1 - 0.02 14.8 0.3 0.75 9.8 0.0 2.8 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Arm PF00514.18 AEO55371.1 - 0.025 14.4 0.5 6.8 6.6 0.0 3.1 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat TPR_11 PF13414.1 AEO55371.1 - 0.14 11.7 0.7 9.8 5.9 0.3 2.7 2 1 1 3 3 3 0 TPR repeat XPG_I_2 PF12813.2 AEO55372.1 - 4.5e-63 213.0 0.0 6.1e-63 212.5 0.0 1.2 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.13 AEO55372.1 - 0.032 14.2 0.0 0.071 13.1 0.0 1.6 1 0 0 1 1 1 0 XPG I-region Pribosyltran_N PF13793.1 AEO55373.1 - 9.1e-42 141.4 0.0 2.2e-41 140.2 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 AEO55373.1 - 2e-34 118.9 0.0 3.1e-29 102.0 0.0 2.4 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 AEO55373.1 - 1.1e-05 25.1 0.3 0.0051 16.5 0.0 2.8 3 0 0 3 3 3 2 Phosphoribosyl transferase domain PAP_assoc PF03828.14 AEO55375.1 - 4.6e-19 68.1 0.0 3.7e-13 49.1 0.0 2.5 2 0 0 2 2 2 2 Cid1 family poly A polymerase Retrotrans_gag PF03732.12 AEO55375.1 - 0.0077 16.2 0.0 0.045 13.8 0.0 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein NTP_transf_2 PF01909.18 AEO55375.1 - 0.008 16.4 0.0 0.019 15.2 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Bud13 PF09736.4 AEO55377.1 - 3.5e-41 140.8 0.2 3.5e-41 140.8 0.1 2.8 2 1 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex Zn_clus PF00172.13 AEO55379.1 - 1.1e-05 25.2 13.1 1.6e-05 24.6 9.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHquinase_I PF01487.10 AEO55380.1 - 1.3e-26 93.6 0.0 2.6e-26 92.6 0.0 1.5 2 0 0 2 2 2 1 Type I 3-dehydroquinase SKI PF01202.17 AEO55380.1 - 1.1e-19 70.8 0.0 1.8e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Shikimate kinase Shikimate_dh_N PF08501.6 AEO55380.1 - 6.5e-15 54.9 0.0 1.7e-14 53.6 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 AEO55380.1 - 6.4e-13 48.9 0.0 1.5e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase PhdYeFM_antitox PF02604.14 AEO55380.1 - 0.015 14.8 0.0 0.059 12.9 0.0 2.0 2 0 0 2 2 2 0 Antitoxin Phd_YefM, type II toxin-antitoxin system DUF1015 PF06245.6 AEO55380.1 - 0.022 13.2 0.0 0.034 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1015) ThiF PF00899.16 AEO55380.1 - 0.045 13.5 0.5 0.1 12.4 0.0 1.8 2 0 0 2 2 2 0 ThiF family 2_5_RNA_ligase2 PF13563.1 AEO55383.1 - 1.1e-33 116.0 0.0 2.6e-33 114.8 0.0 1.7 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily PAP_central PF04928.12 AEO55383.1 - 1.3e-25 89.6 0.0 2.1e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain Exo_endo_phos PF03372.18 AEO55383.1 - 1.7e-13 51.0 0.1 3.3e-13 50.1 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF504 PF04457.7 AEO55383.1 - 1.3e-11 44.4 0.1 2.5e-11 43.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF504) NTP_transf_2 PF01909.18 AEO55383.1 - 3.6e-05 23.9 0.0 0.00011 22.4 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_RNA-bind PF04926.10 AEO55383.1 - 0.0066 15.9 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain DUF4319 PF14203.1 AEO55383.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4319) ResIII PF04851.10 AEO55384.1 - 2.6e-23 82.8 0.0 1.6e-22 80.2 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 AEO55384.1 - 1.6e-14 53.5 0.0 4.1e-14 52.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 AEO55384.1 - 6.1e-14 51.8 0.0 1.9e-13 50.2 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF2075 PF09848.4 AEO55384.1 - 0.0027 16.7 0.0 0.024 13.6 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 AEO55384.1 - 0.0095 16.0 0.1 0.052 13.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain PRRSV_Env PF02340.10 AEO55384.1 - 0.65 9.1 3.0 1.1 8.4 1.1 2.0 2 0 0 2 2 2 0 PRRSV putative envelope protein PI3_PI4_kinase PF00454.22 AEO55387.1 - 4.4e-41 140.9 0.0 6e-41 140.4 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TMEM52 PF14979.1 AEO55387.1 - 0.099 12.5 0.2 0.19 11.6 0.2 1.3 1 0 0 1 1 1 0 Transmembrane 52 Methyltransf_23 PF13489.1 AEO55388.1 - 2.4e-14 53.3 0.0 4e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO55388.1 - 3.4e-11 43.4 0.0 1.2e-10 41.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO55388.1 - 1.6e-09 37.4 0.0 1.3e-08 34.5 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO55388.1 - 7.7e-07 29.6 0.0 2e-05 25.1 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO55388.1 - 8.8e-07 29.3 0.0 2.3e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO55388.1 - 3.2e-05 23.9 0.0 0.00011 22.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO55388.1 - 0.00026 21.3 0.0 0.0012 19.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 AEO55388.1 - 0.0038 17.2 0.0 0.018 15.0 0.0 1.9 1 1 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 AEO55388.1 - 0.0089 15.0 0.0 0.021 13.8 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_29 PF03141.11 AEO55388.1 - 0.032 12.5 0.0 0.057 11.7 0.0 1.4 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Ubie_methyltran PF01209.13 AEO55388.1 - 0.16 11.0 0.0 16 4.5 0.0 2.5 3 0 0 3 3 3 0 ubiE/COQ5 methyltransferase family YqeY PF09424.5 AEO55389.1 - 1.1e-18 67.4 4.9 1.3e-18 67.2 3.4 1.1 1 0 0 1 1 1 1 Yqey-like protein CBP4 PF07960.6 AEO55389.1 - 0.065 12.8 0.3 0.11 12.0 0.2 1.3 1 0 0 1 1 1 0 CBP4 Filo_VP35 PF02097.10 AEO55391.1 - 0.11 11.6 2.1 0.25 10.4 0.6 1.9 2 0 0 2 2 2 0 Filoviridae VP35 Med19 PF10278.4 AEO55391.1 - 5.8 6.5 8.2 14 5.3 5.7 1.6 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 SNF2_N PF00176.18 AEO55392.1 - 2e-68 230.3 0.0 2.9e-68 229.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AEO55392.1 - 1.1e-10 41.2 0.0 2e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HIRAN PF08797.6 AEO55392.1 - 1.3e-06 28.2 0.0 3.4e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 HIRAN domain DEAD PF00270.24 AEO55392.1 - 3.1e-05 23.5 0.0 6.5e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_5 PF14634.1 AEO55392.1 - 0.0027 17.3 3.9 0.0053 16.4 2.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain WW PF00397.21 AEO55392.1 - 0.0099 15.7 1.1 0.0099 15.7 0.7 1.8 2 0 0 2 2 2 1 WW domain DZR PF12773.2 AEO55392.1 - 0.23 11.2 5.3 0.57 10.0 3.7 1.6 1 0 0 1 1 1 0 Double zinc ribbon zf-C3HC4 PF00097.20 AEO55392.1 - 0.34 10.6 3.6 0.8 9.4 2.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Cyt-b5 PF00173.23 AEO55393.1 - 1.5e-17 63.1 0.0 3.4e-17 62.0 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.19 AEO55393.1 - 1.7e-16 60.4 9.8 1.7e-16 60.4 6.8 2.0 1 1 1 2 2 2 1 Fatty acid desaturase Rrn6 PF10214.4 AEO55394.1 - 0.53 8.3 4.2 1 7.3 2.9 1.4 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor HAD_2 PF13419.1 AEO55395.1 - 7.3e-35 120.7 0.3 8.8e-35 120.4 0.2 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 AEO55395.1 - 4e-08 33.9 0.0 1.1e-07 32.4 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 AEO55395.1 - 4.5e-07 29.4 0.0 7.3e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Acid_PPase PF12689.2 AEO55395.1 - 9.4e-05 22.0 0.0 0.0039 16.8 0.0 2.1 2 0 0 2 2 2 1 Acid Phosphatase Med21 PF11221.3 AEO55396.1 - 1.7e-41 141.5 0.8 1.9e-41 141.3 0.6 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Med9 PF07544.8 AEO55396.1 - 0.0063 16.2 0.8 0.013 15.1 0.5 1.9 1 1 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 TMF_DNA_bd PF12329.3 AEO55396.1 - 0.012 15.3 0.4 0.027 14.2 0.3 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Lipase_chap PF03280.9 AEO55396.1 - 0.024 14.1 0.3 0.054 13.0 0.1 1.4 1 1 0 1 1 1 0 Proteobacterial lipase chaperone protein DUF2034 PF10356.4 AEO55397.1 - 7e-28 97.0 0.0 1.2e-26 92.9 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2034) eIF3_subunit PF08597.5 AEO55398.1 - 0.033 13.7 0.7 0.033 13.7 0.5 2.1 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Nup_retrotrp_bd PF10599.4 AEO55398.1 - 0.14 12.8 4.7 0.25 12.0 3.2 1.4 1 0 0 1 1 1 0 Retro-transposon transporting motif Herpes_LMP2 PF07415.6 AEO55398.1 - 2.2 6.7 5.0 3.1 6.2 3.5 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein DUF605 PF04652.11 AEO55398.1 - 6.3 6.0 18.2 7.7 5.7 12.6 1.0 1 0 0 1 1 1 0 Vta1 like Lon_C PF05362.8 AEO55399.1 - 2.5e-64 216.3 0.0 4.9e-64 215.4 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 AEO55399.1 - 9e-38 130.0 0.0 2.2e-37 128.7 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 AEO55399.1 - 4e-22 78.8 0.0 9.9e-22 77.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 AEO55399.1 - 6.7e-09 35.3 0.0 1.6e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 AEO55399.1 - 4.7e-07 29.6 0.0 8.9e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 AEO55399.1 - 1.8e-06 28.0 0.0 4.6e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 AEO55399.1 - 1.9e-05 24.8 0.0 0.00031 20.8 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_PrkA PF08298.6 AEO55399.1 - 3.2e-05 22.7 0.0 6.9e-05 21.7 0.0 1.5 1 0 0 1 1 1 1 PrkA AAA domain AAA_17 PF13207.1 AEO55399.1 - 7.4e-05 23.5 0.0 0.00032 21.5 0.0 2.1 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 AEO55399.1 - 8.5e-05 21.7 0.1 0.001 18.1 0.0 2.5 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 AEO55399.1 - 0.0034 17.3 3.3 0.0091 15.9 0.0 2.9 3 1 0 3 3 3 1 AAA ATPase domain AAA_18 PF13238.1 AEO55399.1 - 0.0068 16.7 0.3 0.029 14.6 0.0 2.3 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.1 AEO55399.1 - 0.0094 15.8 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain SKI PF01202.17 AEO55399.1 - 0.03 14.2 0.0 0.14 12.0 0.0 2.1 2 0 0 2 2 2 0 Shikimate kinase MobB PF03205.9 AEO55399.1 - 0.032 13.9 0.0 0.11 12.1 0.0 2.0 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 AEO55399.1 - 0.039 14.1 0.0 0.16 12.1 0.0 2.2 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.12 AEO55399.1 - 0.043 13.2 0.1 0.12 11.8 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF258 PF03193.11 AEO55399.1 - 0.043 13.0 0.0 0.097 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NTPase_1 PF03266.10 AEO55399.1 - 0.063 12.9 0.1 1 9.0 0.0 2.4 1 1 1 2 2 2 0 NTPase AAA_25 PF13481.1 AEO55399.1 - 0.065 12.6 0.0 0.18 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.20 AEO55400.1 - 1e-13 51.0 0.0 2.4e-12 46.5 0.0 2.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO55400.1 - 6.4e-13 48.3 0.0 5.4e-12 45.3 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Inositol_P PF00459.20 AEO55401.1 - 1.3e-26 93.5 0.0 6e-26 91.3 0.0 2.1 2 1 0 2 2 2 1 Inositol monophosphatase family phage_tail_N PF08400.5 AEO55401.1 - 0.062 13.0 0.0 0.85 9.3 0.0 2.5 3 0 0 3 3 3 0 Prophage tail fibre N-terminal Glyco_hydro_43 PF04616.9 AEO55402.1 - 1.1e-11 44.3 7.1 2.2e-09 36.8 1.8 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 Aminotran_1_2 PF00155.16 AEO55403.1 - 2.4e-30 105.7 0.0 3.6e-30 105.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 AEO55403.1 - 0.083 11.1 0.0 0.46 8.7 0.0 1.9 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_3 PF00202.16 AEO55404.1 - 1.2e-38 132.8 0.0 6.3e-19 68.0 0.0 3.1 2 1 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.1 AEO55404.1 - 7.6e-35 120.3 0.0 2.2e-34 118.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain KH_1 PF00013.24 AEO55405.1 - 3.2e-25 87.5 1.1 1.6e-07 30.8 0.1 6.2 6 0 0 6 6 6 5 KH domain KH_3 PF13014.1 AEO55405.1 - 1.6e-23 81.8 2.4 1.2e-05 24.7 0.0 5.8 5 0 0 5 5 5 5 KH domain Spc97_Spc98 PF04130.8 AEO55406.1 - 6.9e-136 453.7 0.1 6.9e-136 453.7 0.1 1.5 2 0 0 2 2 2 1 Spc97 / Spc98 family Proteasome PF00227.21 AEO55407.1 - 6.2e-57 191.9 0.1 7.8e-57 191.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 AEO55407.1 - 1e-13 50.2 0.0 2.2e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF3137 PF11335.3 AEO55407.1 - 0.019 14.6 0.1 0.31 10.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3137) Fungal_trans_2 PF11951.3 AEO55408.1 - 1.4e-17 63.3 1.0 1.8e-16 59.7 0.7 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO55408.1 - 5.6e-09 35.7 10.4 9.4e-09 35.0 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 AEO55408.1 - 1.7e-06 27.1 0.2 3.6e-06 26.0 0.2 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain YgbA_NO PF11756.3 AEO55408.1 - 1.3 9.0 5.5 6.3 6.8 0.1 2.4 2 0 0 2 2 2 0 Nitrous oxide-stimulated promoter Methyltransf_8 PF05148.10 AEO55409.1 - 4.1e-55 186.7 0.0 5.2e-54 183.1 0.0 2.6 3 0 0 3 3 3 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 AEO55409.1 - 2e-06 28.2 0.0 1.2e-05 25.6 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO55409.1 - 0.0059 16.2 0.0 2.6 7.5 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Dsh_C PF12316.3 AEO55409.1 - 6 6.9 17.9 3.3 7.7 8.7 2.5 2 1 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal SAPS PF04499.10 AEO55409.1 - 8.2 4.9 12.1 1.7 7.2 6.2 1.5 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein UBA PF00627.26 AEO55410.1 - 1.1e-07 31.5 0.0 2.6e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain ubiquitin PF00240.18 AEO55410.1 - 3.7e-06 26.2 0.0 7e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA_4 PF14555.1 AEO55410.1 - 1.7e-05 24.2 0.1 3.8e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain YukD PF08817.5 AEO55410.1 - 0.00069 20.1 0.0 0.0021 18.5 0.0 1.9 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD UN_NPL4 PF11543.3 AEO55410.1 - 0.0062 16.7 0.0 0.01 16.0 0.0 1.4 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 Ubiquitin_2 PF14560.1 AEO55410.1 - 0.11 12.7 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain Acetyltransf_1 PF00583.19 AEO55411.1 - 3.9e-10 39.6 0.0 5.8e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AEO55411.1 - 6.5e-07 29.4 0.0 1.1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 AEO55411.1 - 0.0036 17.3 0.0 0.0067 16.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 AEO55411.1 - 0.012 15.4 0.0 5.4 6.8 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Pribosyltran PF00156.22 AEO55412.1 - 4.6e-16 58.6 0.4 8.1e-16 57.8 0.3 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain NOGCT PF08155.6 AEO55413.1 - 9.7e-30 102.0 2.9 2e-29 101.0 2.0 1.6 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.9 AEO55413.1 - 5.1e-28 96.7 0.7 1.1e-27 95.6 0.3 1.8 2 0 0 2 2 2 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 AEO55413.1 - 8.8e-15 54.6 0.0 2.1e-14 53.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AEO55413.1 - 2.7e-09 36.4 0.0 4.6e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 AEO55413.1 - 0.0017 18.8 0.0 0.0079 16.6 0.0 2.2 1 1 1 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 AEO55413.1 - 0.02 14.3 1.0 0.054 12.9 0.1 2.2 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain GDI PF00996.13 AEO55414.1 - 1.1e-182 607.2 0.0 1.5e-182 606.8 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor zf-UDP PF14569.1 AEO55414.1 - 0.16 11.7 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding RING-finger MRP-L47 PF06984.8 AEO55415.1 - 1e-24 86.2 1.2 1.7e-24 85.5 0.8 1.4 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Clc-like PF07062.7 AEO55415.1 - 0.37 10.0 1.0 0.57 9.3 0.7 1.2 1 0 0 1 1 1 0 Clc-like Fungal_trans PF04082.13 AEO55417.1 - 2.5e-16 59.3 0.0 4.2e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 AEO55417.1 - 1.5e-06 28.1 9.5 4e-05 23.6 1.7 2.6 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 AEO55417.1 - 1.2e-05 25.2 14.7 0.0016 18.6 4.2 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 AEO55417.1 - 0.0041 17.2 5.2 0.0085 16.2 3.6 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 AEO55417.1 - 0.025 14.9 17.4 0.053 13.8 4.7 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type Spc97_Spc98 PF04130.8 AEO55418.1 - 4.6e-76 256.2 0.0 5.6e-76 255.9 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family Eaf7 PF07904.8 AEO55419.1 - 5.3e-30 103.2 0.0 9.9e-30 102.3 0.0 1.5 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 DASH_Ask1 PF08655.5 AEO55419.1 - 1e-23 82.9 0.0 1.6e-23 82.2 0.0 1.3 1 0 0 1 1 1 1 DASH complex subunit Ask1 Med9 PF07544.8 AEO55420.1 - 0.2 11.4 1.6 0.24 11.1 0.5 1.6 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Mucin PF01456.12 AEO55420.1 - 1.7 8.4 25.6 2.2 8.0 17.7 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Plasmodium_Vir PF05795.6 AEO55420.1 - 2.1 7.4 5.0 2.4 7.2 3.4 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CytochromB561_N PF09786.4 AEO55420.1 - 2.3 6.5 13.9 2.5 6.4 9.6 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal KAR9 PF08580.5 AEO55420.1 - 4.2 5.5 16.6 4.6 5.3 11.5 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 p450 PF00067.17 AEO55421.1 - 2.4e-53 181.3 0.0 3.4e-53 180.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Rhodanese PF00581.15 AEO55422.1 - 1.1e-16 61.2 0.0 1.7e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Yip1 PF04893.12 AEO55423.1 - 1.3e-10 41.0 20.6 1.3e-10 41.0 14.2 1.5 1 1 0 1 1 1 1 Yip1 domain ubiquitin PF00240.18 AEO55424.1 - 1.2e-33 114.2 0.5 1.3e-33 114.1 0.4 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 AEO55424.1 - 3.7e-20 71.3 0.6 4e-20 71.2 0.4 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 AEO55424.1 - 1.2e-06 28.7 0.2 4.6e-06 26.7 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 AEO55424.1 - 0.002 17.9 0.1 0.0041 17.0 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Telomere_Sde2 PF13019.1 AEO55424.1 - 0.012 15.2 0.0 0.013 15.2 0.0 1.1 1 0 0 1 1 1 0 Telomere stability and silencing DUF2407 PF10302.4 AEO55424.1 - 0.019 15.1 0.0 0.023 14.9 0.0 1.1 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 AEO55424.1 - 0.11 12.5 0.0 0.34 10.9 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2870) Plexin_cytopl PF08337.7 AEO55424.1 - 0.12 10.6 0.7 0.82 7.9 0.2 1.9 1 1 0 2 2 2 0 Plexin cytoplasmic RasGAP domain RRN7 PF11781.3 AEO55425.1 - 3.6e-06 26.3 3.6 6.8e-06 25.4 2.5 1.4 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 eIF-5a PF01287.15 AEO55426.1 - 2e-25 88.5 0.4 2.9e-25 87.9 0.3 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 AEO55426.1 - 1.9e-05 24.2 1.5 3.8e-05 23.2 1.0 1.5 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 AEO55426.1 - 0.013 15.3 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain Vps52 PF04129.7 AEO55427.1 - 2.5e-121 405.7 0.0 3e-121 405.4 0.0 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.4 AEO55427.1 - 7.9e-05 21.0 0.3 0.00018 19.7 0.2 1.6 1 1 0 1 1 1 1 Exocyst complex component Sec3 Mer2 PF09074.5 AEO55427.1 - 8.9e-05 22.4 0.0 0.00026 20.9 0.0 1.8 1 0 0 1 1 1 1 Mer2 COG2 PF06148.6 AEO55427.1 - 0.007 16.2 0.1 0.021 14.6 0.1 1.8 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.7 AEO55427.1 - 0.0077 16.0 0.1 0.016 14.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) RabGAP-TBC PF00566.13 AEO55428.1 - 2.9e-25 88.9 0.0 3.8e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain MMS1_N PF10433.4 AEO55429.1 - 3.6e-63 213.4 0.0 5.7e-63 212.7 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term PQQ_3 PF13570.1 AEO55429.1 - 0.0035 17.5 0.5 76 3.7 0.0 5.2 6 0 0 6 6 6 0 PQQ-like domain GTP_EFTU PF00009.22 AEO55430.1 - 2.2e-33 115.2 0.0 9.7e-33 113.1 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 AEO55430.1 - 4.1e-18 65.2 0.0 1.3e-17 63.6 0.0 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 AEO55430.1 - 1.2e-11 44.5 5.7 3.8e-08 33.3 0.1 3.4 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 AEO55430.1 - 4e-07 29.9 0.1 2.6e-06 27.3 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 AEO55430.1 - 0.00076 19.9 1.1 0.0023 18.3 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein ATP_bind_1 PF03029.12 AEO55430.1 - 0.002 17.6 0.0 0.0057 16.2 0.0 1.9 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 AEO55430.1 - 0.0079 16.3 0.2 0.12 12.4 0.0 2.9 2 1 0 2 2 2 1 AAA domain GTP_EFTU_D4 PF14578.1 AEO55430.1 - 0.025 14.1 0.0 0.084 12.5 0.0 1.9 1 0 0 1 1 1 0 Elongation factor Tu domain 4 DUF258 PF03193.11 AEO55430.1 - 0.044 12.9 0.1 0.35 10.0 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function, DUF258 Ras PF00071.17 AEO55430.1 - 0.061 12.7 0.0 0.061 12.7 0.0 2.7 2 1 0 2 2 1 0 Ras family FeoB_N PF02421.13 AEO55430.1 - 0.069 12.4 0.1 1.6 8.0 0.1 2.9 2 1 0 2 2 2 0 Ferrous iron transport protein B AAA_16 PF13191.1 AEO55430.1 - 0.18 11.7 0.0 0.18 11.7 0.0 2.8 2 1 0 2 2 1 0 AAA ATPase domain HSP70 PF00012.15 AEO55431.1 - 1.3e-159 532.0 12.6 1.3e-159 532.0 8.7 2.5 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 AEO55431.1 - 1.2e-12 47.1 0.1 6.8e-12 44.6 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 AEO55431.1 - 0.00075 19.3 2.3 0.54 10.1 0.2 3.8 2 2 0 2 2 2 2 Cell division protein FtsA Trans_reg_C PF00486.23 AEO55431.1 - 0.096 12.6 0.1 0.38 10.7 0.0 2.1 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal Macoilin PF09726.4 AEO55431.1 - 0.6 8.3 25.8 0.48 8.6 15.3 1.9 2 0 0 2 2 2 0 Transmembrane protein IncA PF04156.9 AEO55431.1 - 7.2 6.1 10.8 12 5.4 2.8 2.6 2 0 0 2 2 2 0 IncA protein Chitin_synth_2 PF03142.10 AEO55432.1 - 2.8e-25 88.7 2.3 2.1e-22 79.1 1.5 2.4 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 AEO55432.1 - 6.6e-19 68.6 0.0 1.2e-18 67.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 AEO55432.1 - 8.5e-19 68.0 6.9 8.5e-19 68.0 4.8 2.8 2 2 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 AEO55432.1 - 0.018 14.7 0.1 5.6 6.6 0.0 2.6 2 0 0 2 2 2 0 Glycosyl transferase family 2 MIF4G PF02854.14 AEO55433.1 - 3.1e-61 206.4 0.0 1.8e-30 105.9 0.0 3.8 4 0 0 4 4 4 3 MIF4G domain Upf2 PF04050.9 AEO55433.1 - 1.3e-47 161.7 13.1 1.3e-47 161.7 9.1 2.5 3 0 0 3 3 3 1 Up-frameshift suppressor 2 Mo-co_dimer PF03404.11 AEO55434.1 - 2.9e-55 185.4 0.0 5.2e-55 184.6 0.0 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.14 AEO55434.1 - 7.8e-50 168.5 0.0 1.3e-49 167.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.19 AEO55434.1 - 2.3e-28 98.2 0.0 4e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.23 AEO55434.1 - 1.5e-24 85.6 0.0 2.6e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_1 PF00175.16 AEO55434.1 - 2e-24 86.2 0.0 4.1e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 AEO55434.1 - 0.0025 17.7 0.0 0.14 12.0 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain ETC_C1_NDUFA5 PF04716.9 AEO55435.1 - 4e-22 77.4 1.2 2e-21 75.2 0.2 2.3 2 0 0 2 2 2 1 ETC complex I subunit conserved region RNA_pol_I_TF PF04090.7 AEO55436.1 - 5.6e-05 22.5 0.0 0.00034 19.9 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase I specific initiation factor WD40 PF00400.27 AEO55437.1 - 2e-15 55.9 12.2 1.3e-07 31.2 0.1 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat PAS_3 PF08447.6 AEO55439.1 - 3.4e-16 59.1 0.0 8.6e-10 38.5 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.1 AEO55439.1 - 2.1e-10 40.8 0.0 0.00094 19.5 0.0 2.3 2 0 0 2 2 2 2 PAS domain PAS PF00989.19 AEO55439.1 - 4.8e-09 35.9 0.0 0.00037 20.2 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.5 AEO55439.1 - 1.1e-06 28.6 0.0 0.012 15.6 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.1 AEO55439.1 - 0.00045 20.1 0.0 0.0012 18.7 0.0 1.6 2 0 0 2 2 2 1 PAS domain zf-C2H2_2 PF12756.2 AEO55440.1 - 7.7e-25 86.9 8.6 9.5e-23 80.2 2.7 2.3 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 AEO55440.1 - 0.00036 20.5 3.2 0.059 13.5 0.1 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding FPN1 PF06963.7 AEO55441.1 - 4.4e-121 404.2 12.3 5.1e-121 404.0 8.5 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Yip1 PF04893.12 AEO55442.1 - 6.6e-13 48.5 12.4 6.6e-13 48.5 8.6 1.7 2 0 0 2 2 2 1 Yip1 domain DUF1282 PF06930.7 AEO55442.1 - 0.029 14.0 7.6 0.053 13.1 5.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) YIF1 PF03878.10 AEO55442.1 - 0.38 9.8 4.5 0.55 9.3 3.1 1.2 1 0 0 1 1 1 0 YIF1 7TM_transglut PF14402.1 AEO55442.1 - 0.86 8.4 8.6 1.3 7.8 5.9 1.3 1 0 0 1 1 1 0 7 transmembrane helices usually fused to an inactive transglutaminase Na_Ca_ex PF01699.19 AEO55443.1 - 3.7e-25 88.1 20.1 9e-15 54.5 5.2 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein PapJ PF14855.1 AEO55443.1 - 0.011 15.1 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Pilus-assembly fibrillin subunit, chaperone DEAD PF00270.24 AEO55444.1 - 1.3e-25 89.8 0.0 2.2e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.5 AEO55444.1 - 1.1e-11 45.1 0.7 3.3e-11 43.5 0.5 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.26 AEO55444.1 - 2.1e-10 40.3 0.0 7.3e-10 38.5 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AEO55444.1 - 6.4e-06 26.1 0.0 9.5e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Ran_BP1 PF00638.13 AEO55445.1 - 2.7e-13 50.0 0.4 2.8e-05 24.1 0.0 2.4 2 0 0 2 2 2 2 RanBP1 domain MFS_3 PF05977.8 AEO55446.1 - 0.042 11.9 0.0 0.075 11.1 0.0 1.3 1 0 0 1 1 1 0 Transmembrane secretion effector zf-RING_2 PF13639.1 AEO55447.1 - 4.2e-15 55.3 5.8 4.2e-15 55.3 4.0 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 AEO55447.1 - 8.8e-12 44.5 8.6 2.7e-09 36.5 2.2 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 AEO55447.1 - 9.9e-08 31.9 2.3 9.9e-08 31.9 1.6 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 AEO55447.1 - 1.1e-07 31.3 14.5 1.9e-06 27.4 4.1 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AEO55447.1 - 8e-07 28.9 6.9 8e-07 28.9 4.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO55447.1 - 4.3e-06 26.3 11.6 3.7e-05 23.3 2.5 2.3 2 0 0 2 2 2 2 zinc-RING finger domain zf-RING_3 PF14369.1 AEO55447.1 - 0.00037 20.4 7.1 0.00049 20.0 2.5 2.4 2 0 0 2 2 2 1 zinc-finger zf-Apc11 PF12861.2 AEO55447.1 - 0.014 15.2 5.7 0.017 14.9 1.3 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 AEO55447.1 - 0.018 14.5 2.5 0.046 13.2 1.8 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-P11 PF03854.9 AEO55447.1 - 0.028 13.9 2.6 0.07 12.6 1.8 1.7 1 0 0 1 1 1 0 P-11 zinc finger PHD PF00628.24 AEO55447.1 - 0.029 14.0 11.6 0.4 10.4 3.9 2.6 2 0 0 2 2 2 0 PHD-finger Baculo_RING PF05883.6 AEO55447.1 - 0.072 12.9 2.9 0.36 10.6 1.1 2.2 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain HypA PF01155.14 AEO55447.1 - 0.088 12.4 0.3 0.088 12.4 0.2 1.9 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-FPG_IleRS PF06827.9 AEO55447.1 - 0.33 10.6 8.7 20 4.9 0.4 3.5 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS Prok-RING_1 PF14446.1 AEO55447.1 - 0.87 9.3 14.9 0.13 11.9 2.2 3.5 2 2 1 3 3 3 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.1 AEO55447.1 - 2.9 7.5 13.1 1.2 8.8 2.7 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 AEO55447.1 - 4.8 7.1 12.2 0.89 9.4 0.6 2.8 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zinc_ribbon_4 PF13717.1 AEO55447.1 - 5.6 6.7 10.2 18 5.1 0.1 3.6 4 0 0 4 4 4 0 zinc-ribbon domain DZR PF12773.2 AEO55447.1 - 7.6 6.4 7.9 0.92 9.3 0.3 2.4 2 1 0 2 2 2 0 Double zinc ribbon Fis1_TPR_C PF14853.1 AEO55448.1 - 1.5e-25 88.8 1.8 2.1e-25 88.3 1.2 1.2 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 AEO55448.1 - 1.4e-16 59.4 0.0 2.4e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.12 AEO55448.1 - 0.00053 19.7 1.7 0.0013 18.4 1.2 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 AEO55448.1 - 0.011 16.4 0.8 0.02 15.5 0.5 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 AEO55448.1 - 0.072 13.5 0.2 0.16 12.5 0.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 AEO55448.1 - 0.29 10.8 2.7 0.65 9.7 1.8 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Spc24 PF08286.6 AEO55449.1 - 2.7e-43 146.3 0.7 1.5e-41 140.7 0.0 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 Streptin-Immun PF11083.3 AEO55449.1 - 0.00068 19.5 1.3 0.04 13.9 0.0 2.3 1 1 1 2 2 2 1 Lantibiotic streptin immunity protein DUF1633 PF07794.6 AEO55449.1 - 0.0044 15.0 0.2 0.0061 14.5 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1633) Reo_sigmaC PF04582.7 AEO55449.1 - 0.0062 15.7 1.6 0.0078 15.4 1.1 1.1 1 0 0 1 1 1 1 Reovirus sigma C capsid protein AAA_13 PF13166.1 AEO55449.1 - 0.014 13.9 0.7 0.017 13.6 0.5 1.1 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.14 AEO55449.1 - 0.016 13.1 0.4 0.017 12.9 0.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FUSC PF04632.7 AEO55449.1 - 0.033 12.6 5.6 0.033 12.6 3.9 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Troponin PF00992.15 AEO55449.1 - 0.08 13.0 4.8 0.12 12.4 3.4 1.2 1 0 0 1 1 1 0 Troponin APG6 PF04111.7 AEO55449.1 - 0.11 11.5 5.5 0.15 11.0 3.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 MAGSP PF03082.9 AEO55449.1 - 0.16 11.3 1.6 0.23 10.8 1.1 1.2 1 0 0 1 1 1 0 Male accessory gland secretory protein DUF4164 PF13747.1 AEO55449.1 - 0.21 11.7 15.2 0.18 11.9 8.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Nsp1_C PF05064.8 AEO55449.1 - 0.22 11.1 5.4 5.8 6.5 1.1 2.2 1 1 1 2 2 2 0 Nsp1-like C-terminal region MAD PF05557.8 AEO55449.1 - 0.23 9.5 8.6 0.48 8.4 5.9 1.4 1 1 0 1 1 1 0 Mitotic checkpoint protein BRE1 PF08647.6 AEO55449.1 - 0.3 11.0 5.7 0.56 10.2 3.3 1.9 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Seryl_tRNA_N PF02403.17 AEO55449.1 - 0.48 10.4 4.3 2.2 8.3 2.1 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain XhlA PF10779.4 AEO55449.1 - 0.76 9.7 4.1 0.33 10.8 1.1 1.7 2 0 0 2 2 2 0 Haemolysin XhlA Prefoldin_2 PF01920.15 AEO55449.1 - 0.92 9.3 7.6 1.1 9.1 1.2 2.3 1 1 1 2 2 2 0 Prefoldin subunit SlyX PF04102.7 AEO55449.1 - 1.4 9.2 6.9 1.7 9.0 0.6 2.8 1 1 0 2 2 2 0 SlyX HALZ PF02183.13 AEO55449.1 - 1.5 8.6 7.3 0.67 9.7 1.4 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper GAS PF13851.1 AEO55449.1 - 1.8 7.7 8.4 0.89 8.7 1.4 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding HR1 PF02185.11 AEO55449.1 - 1.9 8.2 9.2 7.7 6.3 0.5 2.4 2 0 0 2 2 2 0 Hr1 repeat HAUS-augmin3 PF14932.1 AEO55449.1 - 2.3 7.3 10.5 3.1 6.9 7.3 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 ADIP PF11559.3 AEO55449.1 - 2.5 7.9 13.5 1.1 9.1 5.6 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Viral_P18 PF04521.8 AEO55449.1 - 2.7 7.4 10.3 0.84 9.0 1.8 2.3 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Cortex-I_coil PF09304.5 AEO55449.1 - 2.9 7.9 10.7 4.5 7.3 1.6 2.2 1 1 1 2 2 2 0 Cortexillin I, coiled coil TMF_DNA_bd PF12329.3 AEO55449.1 - 3.6 7.4 10.4 6.4 6.6 2.2 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 AEO55449.1 - 4.2 6.9 15.6 26 4.3 10.9 1.9 1 1 0 1 1 1 0 IncA protein FlxA PF14282.1 AEO55449.1 - 4.6 7.2 7.9 27 4.7 5.5 2.0 1 1 0 1 1 1 0 FlxA-like protein Oleosin PF01277.12 AEO55450.1 - 0.023 14.2 0.8 0.033 13.7 0.5 1.3 1 0 0 1 1 1 0 Oleosin TatD_DNase PF01026.16 AEO55451.1 - 4.5e-30 104.7 0.0 9e-30 103.7 0.0 1.5 1 1 0 1 1 1 1 TatD related DNase Fungal_trans PF04082.13 AEO55452.1 - 1e-26 93.3 0.4 1.4e-26 92.9 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Nol1_Nop2_Fmu PF01189.12 AEO55453.1 - 1.1e-29 103.6 0.0 5.6e-19 68.5 0.0 4.5 4 1 0 4 4 4 3 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 AEO55453.1 - 0.0023 17.9 0.0 0.0049 16.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 AEO55453.1 - 0.07 13.1 0.1 0.24 11.3 0.0 1.9 2 1 0 2 2 2 0 FtsJ-like methyltransferase GTP1_OBG PF01018.17 AEO55454.1 - 9.6e-37 126.0 2.3 3.3e-28 98.2 1.6 2.6 3 0 0 3 3 3 2 GTP1/OBG MMR_HSR1 PF01926.18 AEO55454.1 - 2.2e-19 69.5 0.0 4.1e-19 68.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AEO55454.1 - 6.8e-06 25.4 0.1 2.2e-05 23.8 0.1 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B ArgK PF03308.11 AEO55454.1 - 0.024 13.4 0.0 0.93 8.2 0.0 2.3 2 0 0 2 2 2 0 ArgK protein Arf PF00025.16 AEO55454.1 - 0.042 13.0 0.0 0.6 9.3 0.0 2.1 2 0 0 2 2 2 0 ADP-ribosylation factor family ABC_tran PF00005.22 AEO55454.1 - 0.11 12.8 0.0 0.37 11.0 0.0 1.8 2 0 0 2 2 2 0 ABC transporter Mucin PF01456.12 AEO55456.1 - 0.49 10.1 24.8 0.52 10.0 17.2 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF1154 PF06631.6 AEO55457.1 - 0.13 11.9 0.2 0.17 11.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1154) RNA_pol_Rpb5_C PF01191.14 AEO55458.1 - 1.4e-35 120.6 0.2 2.4e-35 119.9 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 AEO55458.1 - 1.7e-32 111.7 0.0 2.5e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 AEO55458.1 - 0.083 12.6 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Restriction endonuclease Serglycin PF04360.7 AEO55460.1 - 0.12 12.1 6.7 0.14 11.8 3.7 1.8 2 0 0 2 2 2 0 Serglycin Pyridox_oxase_2 PF12766.2 AEO55461.1 - 2e-19 69.7 0.0 4.4e-19 68.6 0.0 1.6 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Glyco_hydro_17 PF00332.13 AEO55462.1 - 6.7e-06 25.3 0.4 1.2e-05 24.5 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 Zip PF02535.17 AEO55463.1 - 1.5e-58 198.3 6.6 1.7e-57 194.8 4.6 2.1 1 1 0 1 1 1 1 ZIP Zinc transporter Bul1_N PF04425.7 AEO55464.1 - 1.1e-06 27.4 1.4 2.5e-05 23.0 0.1 2.7 2 1 1 3 3 3 1 Bul1 N terminus Bul1_C PF04426.7 AEO55464.1 - 4.7e-06 26.0 0.0 3.2e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 Bul1 C terminus Arrestin_N PF00339.24 AEO55464.1 - 0.032 14.0 0.0 0.15 11.9 0.0 2.2 1 1 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain Metallophos PF00149.23 AEO55465.1 - 6.5e-07 28.9 4.7 2.2e-06 27.2 3.3 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 AEO55465.1 - 1.2e-06 28.4 0.0 1.9e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Pex2_Pex12 PF04757.9 AEO55466.1 - 7.6e-55 185.8 0.6 4.5e-54 183.3 1.1 1.6 2 0 0 2 2 2 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 AEO55466.1 - 0.00029 20.8 2.5 0.00053 19.9 1.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AEO55466.1 - 0.011 15.5 1.6 0.019 14.8 1.1 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.1 AEO55466.1 - 0.14 11.8 1.1 0.24 11.0 0.7 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) 4HBT PF03061.17 AEO55467.1 - 1.5e-12 47.4 0.0 2e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 AEO55467.1 - 1.5e-05 24.8 0.0 2.1e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT_2 PF13279.1 AEO55467.1 - 0.079 13.4 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 Thioesterase-like superfamily F-box-like PF12937.2 AEO55468.1 - 2.2e-12 46.4 0.2 4.9e-12 45.3 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 AEO55468.1 - 6.1e-08 32.1 2.8 7e-08 31.9 0.2 2.4 3 0 0 3 3 3 1 F-box domain Fungal_trans PF04082.13 AEO55469.1 - 4.8e-62 209.1 0.0 6.9e-62 208.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain SAP30_Sin3_bdg PF13867.1 AEO55470.1 - 6.6e-12 45.1 0.5 1.3e-10 41.0 0.0 2.2 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Mucin PF01456.12 AEO55470.1 - 0.63 9.8 7.7 0.89 9.3 5.3 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein CTDII PF01556.13 AEO55471.1 - 4.5e-30 103.3 0.2 2e-22 78.8 0.0 3.3 3 0 0 3 3 3 3 DnaJ C terminal domain DnaJ PF00226.26 AEO55471.1 - 1.1e-26 92.3 1.2 2.3e-26 91.2 0.9 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 AEO55471.1 - 4.4e-11 42.6 19.4 7.8e-11 41.8 13.4 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 AEO55471.1 - 4.3 7.0 8.9 10 5.8 0.8 2.5 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family MFS_1 PF07690.11 AEO55472.1 - 8.2e-39 133.3 51.2 8.3e-37 126.7 35.5 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 AEO55472.1 - 5.6e-10 38.0 21.3 1.2e-09 36.9 14.8 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 AEO55472.1 - 6.4e-09 34.8 42.5 4.3e-08 32.1 11.4 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter Zn_clus PF00172.13 AEO55473.1 - 4.3e-09 36.1 14.1 7.9e-09 35.2 9.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 AEO55474.1 - 2.3e-23 82.3 0.0 3.9e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PHD PF00628.24 AEO55475.1 - 2.5e-07 30.2 8.2 5.6e-07 29.1 5.7 1.6 1 0 0 1 1 1 1 PHD-finger SET PF00856.23 AEO55475.1 - 5e-06 26.9 0.0 5e-06 26.9 0.0 3.2 3 2 0 3 3 3 1 SET domain ATP-synt_F PF01990.12 AEO55476.1 - 1.7e-32 111.6 0.1 2e-32 111.4 0.1 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DUF2418 PF10332.4 AEO55477.1 - 1e-35 121.9 0.7 1.8e-35 121.1 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) Aconitase PF00330.15 AEO55480.1 - 3.3e-166 553.3 0.6 1.3e-160 534.9 0.1 2.1 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 AEO55480.1 - 7.5e-44 149.0 0.0 1.3e-43 148.2 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Cupin_8 PF13621.1 AEO55481.1 - 3.5e-28 98.7 0.0 1.8e-27 96.4 0.0 2.0 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 AEO55481.1 - 6.1e-06 25.6 0.0 0.00013 21.3 0.0 2.1 2 0 0 2 2 2 1 Cupin superfamily protein JmjC PF02373.17 AEO55481.1 - 0.012 15.8 0.0 0.14 12.4 0.0 2.1 2 0 0 2 2 2 0 JmjC domain, hydroxylase Methyltransf_23 PF13489.1 AEO55482.1 - 9.8e-18 64.3 0.0 1.5e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO55482.1 - 4.1e-10 40.2 0.1 5.9e-09 36.4 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO55482.1 - 1.4e-09 37.7 0.0 1.8e-08 34.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO55482.1 - 5.4e-08 33.2 0.0 9.2e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO55482.1 - 1.2e-06 28.9 0.0 5.6e-06 26.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO55482.1 - 0.00011 22.4 0.0 0.00028 21.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AEO55482.1 - 0.00027 20.1 0.0 0.003 16.7 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.14 AEO55482.1 - 0.0017 18.4 0.1 0.0035 17.3 0.1 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 AEO55482.1 - 0.024 13.6 0.0 0.063 12.3 0.0 1.7 1 1 0 1 1 1 0 Putative methyltransferase MTS PF05175.9 AEO55482.1 - 0.15 11.4 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain CDC45 PF02724.9 AEO55483.1 - 1.9e-238 792.5 0.4 8.5e-237 787.1 0.3 3.0 1 1 0 1 1 1 1 CDC45-like protein Nop25 PF09805.4 AEO55483.1 - 3 7.9 33.2 0.054 13.5 14.7 2.4 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) MFMR PF07777.6 AEO55483.1 - 9.8 6.0 11.1 6.3 6.6 0.2 2.3 2 0 0 2 2 2 0 G-box binding protein MFMR EF-hand_1 PF00036.27 AEO55484.1 - 2.2e-24 82.8 11.2 3.9e-08 32.0 0.2 4.6 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.1 AEO55484.1 - 3.2e-23 79.4 3.6 1.5e-06 27.6 0.1 5.1 4 1 1 5 5 5 3 EF-hand domain EF-hand_7 PF13499.1 AEO55484.1 - 6.1e-22 77.5 3.4 1.7e-13 50.4 0.3 2.8 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 AEO55484.1 - 2.8e-17 61.1 12.8 2e-05 23.7 0.6 4.6 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 AEO55484.1 - 4.6e-16 58.1 10.7 2.6e-06 26.9 0.4 3.8 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 AEO55484.1 - 2.3e-08 33.7 8.9 0.0043 16.7 0.1 4.1 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 AEO55484.1 - 0.00026 20.8 0.8 0.0025 17.7 0.0 2.6 3 0 0 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.4 AEO55484.1 - 0.0012 18.8 2.0 0.4 10.7 0.1 3.0 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 AEO55484.1 - 0.0013 18.2 0.7 0.56 9.9 0.0 3.5 4 0 0 4 4 4 1 EF hand EF-hand_2 PF09068.6 AEO55484.1 - 0.01 15.9 0.2 1 9.4 0.0 3.0 3 1 0 3 3 3 1 EF hand AMP-binding PF00501.23 AEO55485.1 - 1.8e-84 283.5 0.0 2.7e-84 282.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme CdhD PF03599.11 AEO55485.1 - 0.017 13.6 0.0 0.027 12.9 0.0 1.2 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit Transglut_core PF01841.14 AEO55487.1 - 3.1e-11 43.4 0.0 5.8e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.7 AEO55487.1 - 0.2 10.9 0.0 1.4 8.1 0.0 2.1 2 1 1 3 3 3 0 Transglutaminase-like domain F-box-like PF12937.2 AEO55488.1 - 8.3e-07 28.6 0.0 1.9e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 AEO55488.1 - 4.2e-06 26.2 0.0 9.6e-06 25.1 0.0 1.6 1 0 0 1 1 1 1 F-box domain SR-25 PF10500.4 AEO55488.1 - 0.0056 16.1 10.4 0.0056 16.1 7.2 3.3 3 1 1 4 4 4 1 Nuclear RNA-splicing-associated protein F-box-like_2 PF13013.1 AEO55488.1 - 0.0057 16.3 0.0 0.016 14.9 0.0 1.7 1 0 0 1 1 1 1 F-box-like domain Glycos_transf_4 PF00953.16 AEO55490.1 - 9.4e-32 110.0 11.0 9.4e-32 110.0 7.6 2.2 2 1 0 2 2 2 1 Glycosyl transferase family 4 WD40 PF00400.27 AEO55491.1 - 1.9e-15 56.0 7.7 2.5e-05 23.9 0.0 5.5 6 0 0 6 6 6 4 WD domain, G-beta repeat Apc4_WD40 PF12894.2 AEO55491.1 - 0.039 13.4 0.1 1.4 8.4 0.0 3.3 5 0 0 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain SnAPC_2_like PF11035.3 AEO55491.1 - 0.094 12.1 5.3 0.16 11.4 3.7 1.2 1 0 0 1 1 1 0 Small nuclear RNA activating complex subunit 2-like BNR_2 PF13088.1 AEO55492.1 - 7.4e-07 28.7 0.4 0.00057 19.2 0.0 2.4 1 1 1 2 2 2 2 BNR repeat-like domain BNR PF02012.15 AEO55492.1 - 0.0021 17.6 11.4 0.082 12.7 0.3 4.1 4 0 0 4 4 4 2 BNR/Asp-box repeat MFS_1 PF07690.11 AEO55493.1 - 7.1e-24 84.1 28.0 6.1e-23 81.0 16.3 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily FKBP_C PF00254.23 AEO55496.1 - 1.5e-14 53.7 0.0 1.8e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase ThiF PF00899.16 AEO55497.1 - 6.3e-52 175.0 0.0 1.6e-31 108.9 0.0 2.5 2 0 0 2 2 2 2 ThiF family UBA_e1_C PF09358.5 AEO55497.1 - 8.9e-40 135.7 0.0 1.9e-37 128.1 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 AEO55497.1 - 1.1e-36 124.2 6.4 6.3e-27 92.9 0.2 3.0 3 0 0 3 3 3 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 AEO55497.1 - 4.9e-24 83.4 1.7 7.4e-21 73.2 0.2 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site E3_binding PF02817.12 AEO55497.1 - 0.34 10.5 2.4 0.44 10.2 0.4 2.1 2 0 0 2 2 2 0 e3 binding domain GST_N_2 PF13409.1 AEO55498.1 - 5.8e-23 80.6 0.0 1.6e-22 79.3 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 AEO55498.1 - 5.4e-16 58.2 0.2 1.1e-15 57.1 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 AEO55498.1 - 4.9e-06 26.6 0.1 0.00069 19.7 0.1 2.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 AEO55498.1 - 0.0002 21.3 0.0 0.00043 20.2 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 AEO55498.1 - 0.00054 20.3 0.1 0.0011 19.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Chitin_synth_2 PF03142.10 AEO55499.1 - 7.2e-256 849.6 1.9 9.8e-256 849.2 1.3 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 AEO55499.1 - 4.7e-164 547.1 0.0 6.2e-164 546.7 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.6 AEO55499.1 - 5.2e-19 67.7 0.4 6.5e-18 64.2 0.1 2.5 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.23 AEO55499.1 - 3.6e-18 65.1 0.0 9.5e-14 50.9 0.0 2.7 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.1 AEO55499.1 - 4.5e-16 59.3 0.2 3.8e-13 49.7 0.0 2.6 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 AEO55499.1 - 7e-16 58.5 7.5 7e-16 58.5 5.2 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 AEO55499.1 - 0.00011 21.9 0.0 0.019 14.6 0.0 2.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 AEO55499.1 - 0.00026 20.3 0.4 0.0014 17.9 0.3 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 21 AAA_16 PF13191.1 AEO55499.1 - 0.00027 20.9 0.2 0.0011 18.9 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 AEO55499.1 - 0.0038 17.3 0.1 0.017 15.2 0.0 2.2 1 0 0 1 1 1 1 AAA domain TrwB_AAD_bind PF10412.4 AEO55499.1 - 0.035 12.7 0.0 0.062 11.9 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain MobB PF03205.9 AEO55499.1 - 0.085 12.5 0.1 0.29 10.8 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B G-alpha PF00503.15 AEO55499.1 - 0.096 11.3 0.1 0.48 9.0 0.0 2.1 3 0 0 3 3 3 0 G-protein alpha subunit SRPRB PF09439.5 AEO55499.1 - 0.15 11.2 0.6 1.1 8.4 0.3 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit DUF2592 PF10766.4 AEO55499.1 - 1 8.7 5.9 3.2 7.1 4.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2592) Chitin_synth_2 PF03142.10 AEO55500.1 - 8.3e-228 757.0 0.0 1.1e-227 756.6 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 AEO55500.1 - 1.6e-49 168.5 0.0 2.3e-48 164.7 0.0 2.4 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 AEO55500.1 - 1.3e-18 66.5 0.0 5.1e-11 42.2 0.0 2.8 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.1 AEO55500.1 - 3.6e-18 65.9 2.5 3.6e-18 65.9 1.7 2.1 2 1 0 2 2 2 1 Glycosyl transferase family group 2 DEK_C PF08766.6 AEO55500.1 - 6.8e-16 57.7 3.2 9.8e-15 54.0 1.9 2.7 3 0 0 3 3 3 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.1 AEO55500.1 - 1.7e-15 57.4 0.0 7.3e-13 48.8 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 AEO55500.1 - 1.1e-06 28.0 0.0 2.8e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 AEO55500.1 - 0.0011 18.7 0.0 0.059 13.0 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 DUF663 PF04950.7 AEO55501.1 - 3.3e-90 302.0 0.0 3.3e-90 302.0 0.0 1.7 2 0 0 2 2 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 AEO55501.1 - 4.6e-28 96.5 0.1 1e-26 92.2 0.0 2.6 2 0 0 2 2 2 1 AARP2CN (NUC121) domain AAA_16 PF13191.1 AEO55501.1 - 3.1e-06 27.2 0.0 1.3e-05 25.2 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.22 AEO55501.1 - 4.7e-06 26.1 0.0 0.0017 17.8 0.0 2.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 AEO55501.1 - 6.3e-06 26.3 0.0 1.9e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 AEO55501.1 - 0.00012 22.3 1.0 0.00098 19.4 0.0 2.6 2 0 0 2 2 2 1 ABC transporter MMR_HSR1 PF01926.18 AEO55501.1 - 0.00014 21.7 0.0 0.00042 20.2 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 AEO55501.1 - 0.00019 21.9 0.0 0.00081 19.8 0.0 2.1 1 0 0 1 1 1 1 Miro-like protein NACHT PF05729.7 AEO55501.1 - 0.00024 20.8 0.0 0.00056 19.6 0.0 1.7 1 1 0 1 1 1 1 NACHT domain AAA_33 PF13671.1 AEO55501.1 - 0.00033 20.5 1.1 0.00098 19.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 AEO55501.1 - 0.00039 20.6 0.0 0.00098 19.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 AEO55501.1 - 0.00052 20.8 0.0 0.00052 20.8 0.0 5.0 3 1 0 3 3 2 1 AAA domain AAA_19 PF13245.1 AEO55501.1 - 0.00064 19.4 0.7 0.0019 17.9 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain PduV-EutP PF10662.4 AEO55501.1 - 0.0008 18.9 0.0 0.0026 17.2 0.0 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 AEO55501.1 - 0.00092 18.9 0.0 0.0029 17.3 0.0 1.9 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 AEO55501.1 - 0.002 17.5 0.0 0.006 16.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 AEO55501.1 - 0.003 17.4 0.0 0.0096 15.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 AEO55501.1 - 0.0042 16.5 0.0 0.011 15.2 0.0 1.7 2 0 0 2 2 2 1 AAA-like domain AAA_18 PF13238.1 AEO55501.1 - 0.0058 16.9 0.0 0.0058 16.9 0.0 4.9 4 2 0 4 4 4 1 AAA domain DUF258 PF03193.11 AEO55501.1 - 0.0065 15.6 0.0 0.047 12.8 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 NB-ARC PF00931.17 AEO55501.1 - 0.0077 15.1 1.8 0.037 12.9 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain AAA_24 PF13479.1 AEO55501.1 - 0.012 15.1 0.0 0.032 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 AEO55501.1 - 0.014 14.8 0.0 0.031 13.7 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 AEO55501.1 - 0.015 15.4 0.0 0.047 13.8 0.0 1.9 2 0 0 2 2 1 0 RNA helicase FtsK_SpoIIIE PF01580.13 AEO55501.1 - 0.025 14.0 3.5 0.72 9.2 0.0 2.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family NTPase_1 PF03266.10 AEO55501.1 - 0.026 14.2 0.2 0.026 14.2 0.1 1.9 2 0 0 2 2 1 0 NTPase AAA_21 PF13304.1 AEO55501.1 - 0.61 9.9 0.0 0.61 9.9 0.0 3.2 4 1 0 4 4 4 0 AAA domain Inhibitor_I9 PF05922.11 AEO55502.1 - 3.5e-14 53.1 0.2 3.9e-14 52.9 0.1 1.0 1 0 0 1 1 1 1 Peptidase inhibitor I9 Cupin_2 PF07883.6 AEO55502.1 - 0.083 12.3 0.2 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 Cupin domain DUF2411 PF10304.4 AEO55502.1 - 0.14 11.7 0.5 0.14 11.7 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2411) BCDHK_Adom3 PF10436.4 AEO55503.1 - 4.7e-45 153.0 0.0 7.7e-45 152.3 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 AEO55503.1 - 2.7e-16 59.2 0.0 4.1e-14 52.2 0.0 2.5 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 AEO55503.1 - 0.1 12.2 0.0 0.29 10.7 0.0 1.8 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Radical_SAM PF04055.16 AEO55504.1 - 0.0006 20.0 1.1 0.0012 19.0 0.2 1.9 2 1 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.1 AEO55504.1 - 0.00066 19.8 0.3 0.0013 18.8 0.2 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Kazal_2 PF07648.10 AEO55504.1 - 0.012 15.5 0.6 0.025 14.5 0.4 1.5 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain Fer4_14 PF13394.1 AEO55504.1 - 0.034 14.1 0.3 0.076 13.0 0.2 1.5 1 0 0 1 1 1 0 4Fe-4S single cluster domain DUF1681 PF07933.9 AEO55505.1 - 3.3e-53 179.5 0.0 4.8e-53 178.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) DUF3628 PF12300.3 AEO55505.1 - 0.08 12.9 11.4 0.17 11.9 7.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3628) IF-2B PF01008.12 AEO55506.1 - 3.4e-35 121.4 0.1 4.7e-35 120.9 0.1 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family HEM4 PF02602.10 AEO55506.1 - 0.047 12.9 0.5 2.1 7.5 0.0 2.5 2 1 0 2 2 2 0 Uroporphyrinogen-III synthase HemD 4_1_CTD PF05902.8 AEO55506.1 - 0.048 13.7 0.1 0.099 12.6 0.0 1.5 1 0 0 1 1 1 0 4.1 protein C-terminal domain (CTD) Methyltransf_33 PF10017.4 AEO55507.1 - 5.7e-30 103.8 0.0 1.1e-29 102.9 0.0 1.5 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 AEO55507.1 - 3.1e-18 66.0 2.8 3.3e-11 43.0 0.2 3.0 2 1 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 AEO55507.1 - 7.2e-09 36.0 1.5 1.8e-08 34.7 0.2 2.3 3 0 0 3 3 3 1 DinB superfamily Methyltransf_25 PF13649.1 AEO55507.1 - 0.032 14.6 0.0 0.08 13.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain GFA PF04828.9 AEO55508.1 - 0.0006 19.7 0.7 0.0006 19.7 0.5 1.8 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme PfkB PF00294.19 AEO55509.1 - 2.9e-52 177.7 1.1 3.7e-52 177.3 0.8 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase zf-C2H2_4 PF13894.1 AEO55510.1 - 0.053 13.8 17.6 0.075 13.4 0.4 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger NOA36 PF06524.7 AEO55510.1 - 0.088 12.0 2.2 0.14 11.3 1.6 1.2 1 0 0 1 1 1 0 NOA36 protein eIF3_subunit PF08597.5 AEO55511.1 - 1.3e-66 224.6 22.3 1.5e-66 224.5 15.5 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Nop53 PF07767.6 AEO55511.1 - 0.059 12.3 27.1 0.13 11.1 14.1 2.1 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) DUF2413 PF10310.4 AEO55511.1 - 0.51 9.0 23.0 0.041 12.7 11.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2413) PRP4 PF08799.6 AEO55511.1 - 0.68 9.2 4.7 1.4 8.2 3.3 1.6 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Spore_coat_CotO PF14153.1 AEO55511.1 - 1 8.7 14.5 0.06 12.7 5.5 1.9 2 0 0 2 2 2 0 Spore coat protein CotO FNIP_N PF14636.1 AEO55511.1 - 1.5 9.2 9.3 0.17 12.3 3.0 1.8 2 0 0 2 2 2 0 Folliculin-interacting protein N-terminus Plasmodium_Vir PF05795.6 AEO55511.1 - 1.8 7.7 6.5 0.69 9.0 1.6 2.0 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Rrn6 PF10214.4 AEO55511.1 - 4.2 5.3 7.0 0.62 8.0 2.2 1.4 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor MDM31_MDM32 PF08118.6 AEO55512.1 - 6.8e-185 615.3 0.0 1.9e-184 613.8 0.0 1.6 1 1 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins DUF3825 PF12873.2 AEO55512.1 - 0.046 12.8 0.0 0.085 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3825) KH_1 PF00013.24 AEO55513.1 - 1.6e-05 24.4 0.7 4e-05 23.1 0.5 1.7 1 0 0 1 1 1 1 KH domain Rad60-SLD PF11976.3 AEO55514.1 - 5.8e-15 54.7 0.0 4.1e-14 52.0 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like adh_short PF00106.20 AEO55515.1 - 3.9e-22 78.9 2.7 5.3e-22 78.4 1.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO55515.1 - 1.3e-18 67.7 0.1 1.9e-18 67.1 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO55515.1 - 1.7e-08 34.3 2.8 8.1e-08 32.1 1.9 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 AEO55515.1 - 4e-06 26.4 0.4 3.4e-05 23.3 0.3 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 AEO55515.1 - 0.0097 16.3 0.6 0.019 15.3 0.4 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.10 AEO55515.1 - 0.023 13.6 0.1 0.032 13.1 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 AEO55515.1 - 0.068 13.1 2.1 0.28 11.1 0.5 2.2 2 1 0 2 2 2 0 NADH(P)-binding Shikimate_DH PF01488.15 AEO55515.1 - 0.092 12.8 0.3 0.2 11.7 0.2 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PDZ PF00595.19 AEO55515.1 - 0.13 12.4 0.1 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) MFS_1 PF07690.11 AEO55516.1 - 6.2e-31 107.3 30.8 1.1e-30 106.5 21.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO55516.1 - 3.3e-05 22.6 14.7 3.3e-05 22.6 10.2 4.1 3 2 0 4 4 4 3 Sugar (and other) transporter DUF4381 PF14316.1 AEO55516.1 - 1.1 9.3 0.0 1.1 9.3 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) CFEM PF05730.6 AEO55517.1 - 2e-12 46.7 10.3 2e-12 46.7 7.1 1.8 2 0 0 2 2 2 1 CFEM domain Sporozoite_P67 PF05642.6 AEO55517.1 - 1.6 6.4 10.7 2 6.1 7.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Period_C PF12114.3 AEO55517.1 - 4.7 6.7 6.7 7 6.2 4.6 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Herpes_capsid PF06112.6 AEO55517.1 - 4.8 7.2 15.2 7 6.6 10.5 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF2300 PF10062.4 AEO55519.1 - 0.031 14.0 1.6 0.2 11.4 0.5 2.5 2 0 0 2 2 2 0 Predicted secreted protein (DUF2300) adh_short PF00106.20 AEO55520.1 - 1.2e-33 116.3 1.6 1.6e-33 115.9 1.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO55520.1 - 4e-24 85.7 0.5 1.8e-23 83.5 0.3 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO55520.1 - 4.7e-16 58.9 0.8 7e-16 58.4 0.5 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 AEO55520.1 - 0.00024 20.8 1.1 0.00037 20.2 0.8 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.16 AEO55520.1 - 0.0024 17.7 0.3 0.0043 16.9 0.2 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain TrkA_N PF02254.13 AEO55520.1 - 0.044 13.7 0.5 0.074 13.0 0.3 1.4 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.9 AEO55520.1 - 0.072 12.4 0.2 0.13 11.6 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Epimerase PF01370.16 AEO55520.1 - 0.079 12.3 0.1 0.098 12.0 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Glycos_transf_2 PF00535.21 AEO55521.1 - 2.7e-31 108.5 0.0 3.3e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 AEO55521.1 - 7.3e-15 55.3 0.0 1.6e-14 54.2 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 AEO55521.1 - 1.8e-06 27.2 0.0 2.4e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 AEO55521.1 - 0.00012 21.4 0.0 0.00017 20.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.1 AEO55521.1 - 0.012 15.8 0.0 0.02 15.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 E1-E2_ATPase PF00122.15 AEO55522.1 - 1e-63 214.4 3.1 1.7e-63 213.7 2.1 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 AEO55522.1 - 3.2e-35 121.3 1.7 3.2e-35 121.3 1.2 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 AEO55522.1 - 2.1e-27 96.9 0.0 2.9e-26 93.2 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AEO55522.1 - 1.1e-20 73.3 0.0 2.1e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 AEO55522.1 - 1.9e-14 52.8 0.0 7.1e-14 51.0 0.0 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 AEO55522.1 - 2e-11 44.4 0.0 5.9e-11 42.8 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 AEO55522.1 - 1.8e-07 31.0 0.3 1.2e-05 25.0 0.3 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase AT_hook PF02178.14 AEO55523.1 - 0.9 9.4 9.1 0.092 12.4 2.5 2.5 3 0 0 3 3 3 0 AT hook motif DUF221 PF02714.10 AEO55524.1 - 9e-97 323.8 12.1 9e-97 323.8 8.4 1.8 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 AEO55524.1 - 1.2e-40 138.5 4.9 3.7e-40 137.0 3.4 1.9 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 AEO55524.1 - 9.5e-16 58.0 0.3 1.9e-15 57.1 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) TMA7 PF09072.5 AEO55525.1 - 1e-27 96.3 17.5 1.1e-27 96.2 12.1 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Pkinase PF00069.20 AEO55526.1 - 1.4e-52 178.4 0.0 1.9e-52 177.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO55526.1 - 6.1e-23 81.2 0.0 1.1e-22 80.3 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 AEO55526.1 - 0.044 12.5 0.1 0.065 12.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 AEO55526.1 - 0.15 11.4 0.0 0.31 10.3 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.20 AEO55528.1 - 1.1e-53 182.0 0.0 2.3e-41 141.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AEO55528.1 - 5.5e-27 94.4 0.0 2.1e-19 69.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 AEO55528.1 - 0.00082 19.1 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 AEO55528.1 - 0.0021 17.0 0.0 0.41 9.5 0.0 2.6 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.9 AEO55528.1 - 0.003 16.6 0.0 0.0048 15.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family UL11 PF11094.3 AEO55528.1 - 0.028 14.2 0.0 0.065 13.0 0.0 1.6 1 0 0 1 1 1 0 Membrane-associated tegument protein YrbL-PhoP_reg PF10707.4 AEO55528.1 - 0.049 12.9 0.0 0.086 12.1 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 AEO55528.1 - 0.082 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.6 AEO55528.1 - 0.14 10.9 0.2 0.25 10.0 0.0 1.4 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase HlyIII PF03006.15 AEO55530.1 - 1.4e-57 194.6 17.9 1.7e-57 194.4 12.4 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF4231 PF14015.1 AEO55530.1 - 0.033 14.1 4.9 0.37 10.7 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) P5-ATPase PF12409.3 AEO55530.1 - 1.4 8.8 4.7 3.1 7.6 3.2 1.6 1 0 0 1 1 1 0 P5-type ATPase cation transporter WD40 PF00400.27 AEO55531.1 - 0.0027 17.5 8.4 0.31 10.9 0.3 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat SDA1 PF05285.7 AEO55531.1 - 0.003 16.8 12.9 0.013 14.8 0.7 2.2 2 0 0 2 2 2 2 SDA1 FAD_binding_4 PF01565.18 AEO55533.1 - 1.7e-17 63.2 0.9 3.1e-17 62.3 0.3 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 AEO55533.1 - 2.1e-08 33.9 0.2 1e-07 31.6 0.0 2.1 2 0 0 2 2 2 1 Berberine and berberine like DUF3407 PF11887.3 AEO55533.1 - 0.0025 17.1 0.6 0.13 11.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3407) DUF3404 PF11884.3 AEO55533.1 - 0.14 11.0 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3404) TauD PF02668.11 AEO55534.1 - 5.6e-57 193.3 1.5 6.9e-57 193.0 1.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TRIC PF05197.8 AEO55536.1 - 0.032 13.6 0.1 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 TRIC channel APH PF01636.18 AEO55539.1 - 0.00012 21.8 0.2 0.00012 21.8 0.1 2.6 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 AEO55539.1 - 0.00076 19.1 0.0 0.0015 18.1 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 AEO55539.1 - 0.012 14.8 0.0 0.027 13.6 0.0 1.6 1 0 0 1 1 1 0 Protein kinase domain HSDR_N_2 PF13588.1 AEO55539.1 - 0.029 14.1 0.0 3.6 7.4 0.0 2.6 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) Macoilin PF09726.4 AEO55539.1 - 2.3 6.3 18.5 2.2 6.4 7.7 2.3 2 0 0 2 2 2 0 Transmembrane protein Phage_Gp23 PF10669.4 AEO55539.1 - 3.5 7.7 5.7 8.1 6.5 3.9 1.6 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) NAD_binding_1 PF00175.16 AEO55541.1 - 3.4e-26 91.9 0.0 4.9e-26 91.4 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 AEO55541.1 - 1.8e-14 53.6 0.0 3e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 AEO55541.1 - 6.2e-11 42.4 0.0 2.2e-05 24.4 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain MarR_2 PF12802.2 AEO55542.1 - 0.0021 17.6 0.1 0.0025 17.4 0.1 1.3 1 1 0 1 1 1 1 MarR family HTH_IclR PF09339.5 AEO55542.1 - 0.081 12.5 0.2 0.15 11.7 0.2 1.4 1 1 0 1 1 1 0 IclR helix-turn-helix domain DEAD PF00270.24 AEO55543.1 - 6.4e-42 142.9 0.0 1e-41 142.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO55543.1 - 5.8e-16 58.1 0.0 1.2e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 AEO55543.1 - 2.4e-14 52.6 0.0 5.1e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 AEO55543.1 - 0.02 14.7 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Glyco_hydro_7 PF00840.15 AEO55544.1 - 1.4e-218 725.4 24.3 1.8e-218 725.1 16.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.13 AEO55544.1 - 8.5e-15 54.1 5.5 8.5e-15 54.1 3.8 4.5 5 1 1 6 6 6 1 Fungal cellulose binding domain Colipase-like PF15083.1 AEO55544.1 - 1.6 8.6 6.1 0.14 12.1 0.6 2.0 2 1 0 2 2 2 0 Colipase-like DUF3786 PF12654.2 AEO55545.1 - 0.077 12.2 0.3 0.097 11.9 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3786) CBF PF03914.12 AEO55545.1 - 0.18 11.2 1.3 0.22 10.9 0.9 1.2 1 0 0 1 1 1 0 CBF/Mak21 family TypeIII_RM_meth PF12564.3 AEO55545.1 - 1.5 8.8 6.3 1.6 8.8 0.3 2.6 1 1 1 2 2 2 0 Type III restriction/modification enzyme methylation subunit DUF4237 PF14021.1 AEO55546.1 - 8.1e-32 109.3 0.2 1.5e-31 108.4 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4237) PLDc PF00614.17 AEO55547.1 - 1.4e-15 56.4 1.7 2.3e-07 30.3 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 AEO55547.1 - 2.2e-13 50.0 0.0 4.3e-05 23.2 0.0 3.5 3 0 0 3 3 3 3 PLD-like domain GLTP PF08718.6 AEO55548.1 - 1.5e-46 158.1 0.1 9e-46 155.6 0.0 1.8 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) P4Ha_N PF08336.6 AEO55548.1 - 0.21 11.3 1.0 0.8 9.5 0.3 2.1 3 0 0 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Ank_2 PF12796.2 AEO55549.1 - 1.5e-64 214.3 20.9 4.5e-15 55.7 0.3 8.5 3 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 AEO55549.1 - 2.3e-57 188.0 23.2 1.6e-10 40.2 0.0 14.7 14 1 0 14 14 14 11 Ankyrin repeat Ank_4 PF13637.1 AEO55549.1 - 3.1e-45 151.7 19.0 4.7e-07 30.1 0.0 9.7 9 1 1 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 AEO55549.1 - 8.4e-41 133.9 23.6 2.1e-08 33.6 0.0 14.8 15 0 0 15 15 15 7 Ankyrin repeat Ank_5 PF13857.1 AEO55549.1 - 7.7e-36 121.3 20.8 3.2e-07 30.3 0.0 10.0 9 2 2 11 11 11 6 Ankyrin repeats (many copies) F-box-like PF12937.2 AEO55549.1 - 0.085 12.5 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 F-box-like Fungal_trans PF04082.13 AEO55551.1 - 0.027 13.3 0.0 0.045 12.6 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF35_N PF12172.3 AEO55551.1 - 1.1 9.2 3.8 6.2 6.8 0.0 3.2 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) SNF5 PF04855.7 AEO55552.1 - 5.8e-81 271.5 0.0 9.9e-80 267.5 0.0 2.1 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.22 AEO55552.1 - 5e-05 22.5 1.6 5e-05 22.5 1.1 2.0 2 0 0 2 2 2 1 GATA zinc finger RNA_ligase PF09414.5 AEO55553.1 - 2e-11 44.0 0.0 5.4e-11 42.6 0.0 1.6 1 1 0 1 1 1 1 RNA ligase Exo_endo_phos PF03372.18 AEO55554.1 - 1.2e-12 48.2 0.6 1.8e-12 47.7 0.4 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 AEO55554.1 - 4.7e-05 22.9 0.0 0.0015 18.1 0.0 2.5 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase FGGY_C PF02782.11 AEO55554.1 - 0.11 12.1 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain RVT_1 PF00078.22 AEO55556.1 - 6.4e-06 25.6 0.6 7.3e-06 25.4 0.4 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RasGAP_C PF03836.10 AEO55556.1 - 0.082 12.5 0.1 0.093 12.4 0.0 1.1 1 0 0 1 1 1 0 RasGAP C-terminus DUF4139 PF13598.1 AEO55557.1 - 7.1e-59 199.6 14.4 3.1e-45 154.8 0.4 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF4139) DUF4140 PF13600.1 AEO55557.1 - 8.8e-10 38.9 9.7 8.8e-10 38.9 6.7 3.8 2 1 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) Nucleoporin_FG PF13634.1 AEO55557.1 - 0.47 10.6 15.7 1 9.6 10.3 1.9 1 1 0 1 1 1 0 Nucleoporin FG repeat region SPX PF03105.14 AEO55557.1 - 1.2 8.8 11.8 1.9 8.1 8.2 1.3 1 0 0 1 1 1 0 SPX domain Tom22 PF04281.8 AEO55557.1 - 8.6 5.8 13.0 3.1 7.3 2.8 2.5 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 DUF998 PF06197.8 AEO55558.1 - 0.25 10.6 2.1 2.9 7.1 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF998) DUF1576 PF07613.6 AEO55559.1 - 0.039 13.4 1.6 0.073 12.5 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1576) tRNA-synt_1c PF00749.16 AEO55560.1 - 1.4e-99 332.6 0.0 2.2e-99 332.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 AEO55560.1 - 2.4e-34 118.5 0.0 5.9e-34 117.2 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain NARP1 PF12569.3 AEO55560.1 - 0.58 8.8 7.6 0.97 8.1 5.2 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Macro PF01661.16 AEO55561.1 - 2.3e-39 133.9 0.0 3.5e-39 133.3 0.0 1.3 1 0 0 1 1 1 1 Macro domain ABC_tran PF00005.22 AEO55562.1 - 1.1e-49 168.1 0.5 9.4e-25 87.5 0.1 3.9 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 AEO55562.1 - 2.9e-17 63.5 0.5 0.0005 20.1 0.0 4.3 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 AEO55562.1 - 2.4e-16 59.6 0.0 1.6e-06 27.5 0.0 3.6 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 AEO55562.1 - 4e-10 39.0 0.0 0.0013 18.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 AEO55562.1 - 9.5e-09 35.8 6.4 0.00042 20.7 0.0 3.6 4 0 0 4 4 3 2 AAA domain AAA_22 PF13401.1 AEO55562.1 - 2e-08 34.4 0.0 0.00035 20.7 0.0 3.5 3 0 0 3 3 2 2 AAA domain AAA_17 PF13207.1 AEO55562.1 - 2.7e-08 34.6 0.0 0.0037 18.0 0.0 3.0 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 AEO55562.1 - 4.6e-08 32.4 0.0 0.00045 19.4 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 AEO55562.1 - 4.9e-07 29.7 0.0 0.0048 16.8 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_15 PF13175.1 AEO55562.1 - 1.1e-06 28.0 4.7 0.046 12.7 0.0 4.6 3 2 2 5 5 5 2 AAA ATPase domain AAA_28 PF13521.1 AEO55562.1 - 2e-06 27.8 0.0 0.026 14.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 AEO55562.1 - 2.4e-06 27.4 0.0 0.13 12.1 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 AEO55562.1 - 2.9e-06 26.9 0.1 0.26 10.6 0.0 3.8 4 0 0 4 4 4 2 AAA-like domain Dynamin_N PF00350.18 AEO55562.1 - 3.4e-06 26.9 0.0 0.00055 19.8 0.0 2.8 2 0 0 2 2 2 1 Dynamin family SbcCD_C PF13558.1 AEO55562.1 - 5.5e-06 26.2 0.0 0.025 14.5 0.0 3.2 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit Miro PF08477.8 AEO55562.1 - 6.2e-06 26.6 0.1 0.029 14.8 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_18 PF13238.1 AEO55562.1 - 7.9e-06 26.2 0.5 0.13 12.5 0.0 3.5 3 0 0 3 3 2 2 AAA domain AAA PF00004.24 AEO55562.1 - 1.2e-05 25.5 0.0 0.52 10.5 0.0 4.5 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) ArgK PF03308.11 AEO55562.1 - 1.6e-05 23.8 1.1 0.21 10.3 0.0 3.2 3 0 0 3 3 3 2 ArgK protein MobB PF03205.9 AEO55562.1 - 3.7e-05 23.4 0.0 0.34 10.6 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 AEO55562.1 - 5.4e-05 22.7 0.0 0.066 12.6 0.0 2.8 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 AEO55562.1 - 6.4e-05 23.0 0.4 0.68 9.8 0.0 4.1 4 0 0 4 4 4 1 AAA ATPase domain RNA_helicase PF00910.17 AEO55562.1 - 7.3e-05 22.9 0.0 0.62 10.2 0.0 2.8 2 0 0 2 2 2 2 RNA helicase NACHT PF05729.7 AEO55562.1 - 0.00016 21.3 0.0 0.08 12.5 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_14 PF13173.1 AEO55562.1 - 0.00025 20.9 0.0 1.9 8.4 0.0 3.5 3 0 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 AEO55562.1 - 0.00031 20.5 0.0 1.1 8.8 0.0 2.9 2 0 0 2 2 2 2 Archaeal ATPase DUF87 PF01935.12 AEO55562.1 - 0.0011 18.8 0.2 0.91 9.2 0.0 3.5 3 0 0 3 3 3 1 Domain of unknown function DUF87 AAA_30 PF13604.1 AEO55562.1 - 0.0025 17.4 0.1 6 6.3 0.0 3.6 4 0 0 4 4 4 0 AAA domain HEAT_2 PF13646.1 AEO55562.1 - 0.0028 17.9 6.3 0.058 13.6 1.4 3.3 3 1 0 3 3 2 1 HEAT repeats cobW PF02492.14 AEO55562.1 - 0.0029 17.0 0.1 3.1 7.2 0.0 3.2 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain ATP-synt_ab PF00006.20 AEO55562.1 - 0.0035 16.8 0.0 2.4 7.6 0.0 2.6 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_13 PF13166.1 AEO55562.1 - 0.0048 15.4 8.4 1.3 7.3 0.0 4.3 4 1 0 4 4 4 2 AAA domain AAA_25 PF13481.1 AEO55562.1 - 0.0066 15.8 0.0 6.1 6.2 0.0 3.2 3 0 0 3 3 2 0 AAA domain ParcG PF10274.4 AEO55562.1 - 0.0074 16.1 1.0 8.5 6.2 0.0 3.2 1 1 1 3 3 3 0 Parkin co-regulated protein MutS_V PF00488.16 AEO55562.1 - 0.0075 15.6 0.1 0.72 9.2 0.0 2.4 2 0 0 2 2 2 1 MutS domain V Septin PF00735.13 AEO55562.1 - 0.0081 15.2 0.6 0.98 8.3 0.0 2.8 3 0 0 3 3 3 1 Septin ATP_bind_1 PF03029.12 AEO55562.1 - 0.014 14.9 0.0 7.5 6.0 0.0 2.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.13 AEO55562.1 - 0.019 14.4 0.2 5.1 6.5 0.0 3.3 3 0 0 3 3 3 0 FtsK/SpoIIIE family Zeta_toxin PF06414.7 AEO55562.1 - 0.026 13.6 0.0 5.6 6.0 0.0 2.8 2 0 0 2 2 2 0 Zeta toxin T2SE PF00437.15 AEO55562.1 - 0.03 13.2 0.1 2.7 6.8 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein Mg_chelatase PF01078.16 AEO55562.1 - 0.038 13.1 0.0 3.1 6.9 0.0 2.8 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.10 AEO55562.1 - 0.055 12.1 0.0 4.5 5.8 0.0 2.3 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein PRK PF00485.13 AEO55562.1 - 0.055 13.0 0.0 1.7 8.1 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Cnd1 PF12717.2 AEO55562.1 - 0.062 13.1 0.0 0.78 9.5 0.0 2.4 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 AEO55562.1 - 8.7 6.9 9.1 59 4.3 0.3 5.3 5 1 1 6 6 4 0 HEAT-like repeat CsbD PF05532.7 AEO55563.1 - 3.7e-10 39.3 3.7 8.2e-05 22.1 0.2 2.2 1 1 1 2 2 2 2 CsbD-like Fungal_trans PF04082.13 AEO55565.1 - 9.8e-18 63.9 0.3 1.6e-17 63.2 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO55565.1 - 4.8e-08 32.7 10.6 7.9e-08 32.0 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 AEO55566.1 - 2.2e-20 72.6 0.0 4.8e-20 71.5 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO55566.1 - 8.3e-07 28.8 14.0 1.4e-06 28.0 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_11 PF13414.1 AEO55567.1 - 0.013 15.1 0.4 0.093 12.3 0.0 2.3 2 0 0 2 2 2 0 TPR repeat DOMON PF03351.12 AEO55568.1 - 0.00028 20.8 0.0 0.00048 20.0 0.0 1.4 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.11 AEO55568.1 - 0.0012 18.7 6.8 0.0012 18.7 4.7 2.0 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 EphA2_TM PF14575.1 AEO55568.1 - 0.076 13.4 0.0 1.1 9.7 0.0 2.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Cytochrom_B_N PF00033.14 AEO55568.1 - 0.76 9.1 16.5 0.74 9.1 8.8 2.6 1 1 1 2 2 2 0 Cytochrome b(N-terminal)/b6/petB DUF4064 PF13273.1 AEO55568.1 - 1.8 8.6 5.7 0.76 9.9 1.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) Pkinase PF00069.20 AEO55569.1 - 4.7e-27 94.7 0.0 4e-26 91.7 0.0 2.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO55569.1 - 6.8e-05 22.0 0.0 0.16 10.9 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase UQ_con PF00179.21 AEO55569.1 - 0.031 13.7 0.0 0.055 12.9 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme RIO1 PF01163.17 AEO55569.1 - 0.13 11.6 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 RIO1 family DUF605 PF04652.11 AEO55570.1 - 3 7.1 9.4 3.2 7.0 6.5 1.2 1 0 0 1 1 1 0 Vta1 like PPR_2 PF13041.1 AEO55571.1 - 6.7e-56 186.0 3.0 1.6e-10 40.8 0.0 14.3 10 2 5 15 15 15 12 PPR repeat family PPR_3 PF13812.1 AEO55571.1 - 1.4e-30 102.9 24.0 2.5e-06 27.3 0.0 16.5 19 0 0 19 19 19 5 Pentatricopeptide repeat domain PPR PF01535.15 AEO55571.1 - 1.1e-27 94.0 26.5 1.8e-05 24.4 0.0 15.1 20 0 0 20 20 20 6 PPR repeat PPR_1 PF12854.2 AEO55571.1 - 4.7e-24 83.5 0.0 1.8e-08 33.6 0.0 9.1 9 0 0 9 9 9 3 PPR repeat RPM2 PF08579.6 AEO55571.1 - 3.8e-05 23.8 0.0 0.0017 18.4 0.0 3.4 4 0 0 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) TPR_14 PF13428.1 AEO55571.1 - 0.014 15.9 14.6 60 4.6 0.2 9.4 11 0 0 11 11 11 0 Tetratricopeptide repeat DUF4164 PF13747.1 AEO55571.1 - 0.044 13.9 4.1 0.09 12.9 1.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Sel1 PF08238.7 AEO55571.1 - 0.045 14.3 0.5 23 5.8 0.0 3.9 3 0 0 3 3 3 0 Sel1 repeat ECSIT PF06239.6 AEO55571.1 - 0.11 11.3 0.0 9.1 5.0 0.0 3.1 3 0 0 3 3 3 0 Evolutionarily conserved signalling intermediate in Toll pathway GHMP_kinases_N PF00288.21 AEO55572.1 - 2e-14 53.4 1.0 2e-14 53.4 0.7 2.2 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 AEO55572.1 - 5.9e-08 32.7 0.0 1.5e-07 31.4 0.0 1.7 1 1 0 1 1 1 1 GHMP kinases C terminal Aldedh PF00171.17 AEO55574.1 - 1.3e-135 452.3 0.0 1.4e-135 452.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 AEO55574.1 - 4.5e-07 28.9 0.0 6.5e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 AEO55574.1 - 0.0043 16.2 0.0 0.79 8.9 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) GSIII_N PF12437.3 AEO55574.1 - 0.13 11.5 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 Glutamine synthetase type III N terminal RRM_6 PF14259.1 AEO55575.1 - 8.2e-09 35.3 0.0 2.5e-08 33.8 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AEO55575.1 - 8.9e-08 31.6 0.0 2.9e-05 23.6 0.0 2.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO55575.1 - 3.4e-05 23.5 0.0 0.00052 19.8 0.0 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF572 PF04502.8 AEO55575.1 - 0.19 10.9 18.6 0.32 10.1 3.6 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) NMD3 PF04981.8 AEO55576.1 - 2.9e-72 242.6 4.5 2.9e-72 242.6 3.1 1.5 2 0 0 2 2 2 1 NMD3 family DUF35_N PF12172.3 AEO55576.1 - 0.092 12.6 3.0 0.17 11.8 0.1 2.7 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) FYVE PF01363.16 AEO55576.1 - 0.11 12.4 5.9 0.54 10.1 2.0 2.3 2 0 0 2 2 2 0 FYVE zinc finger DZR PF12773.2 AEO55576.1 - 0.48 10.2 4.7 0.91 9.3 1.6 2.3 2 0 0 2 2 2 0 Double zinc ribbon TPR_11 PF13414.1 AEO55577.1 - 2.3e-15 55.9 5.6 2.2e-14 52.8 1.3 2.5 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 AEO55577.1 - 1.3e-08 34.0 1.7 0.0032 16.9 0.1 3.8 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 AEO55577.1 - 3.6e-08 32.7 1.9 0.00056 19.6 0.0 3.8 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 AEO55577.1 - 5.9e-06 26.1 0.9 5.9e-06 26.1 0.6 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 AEO55577.1 - 6.3e-05 23.0 0.5 0.00013 22.0 0.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 AEO55577.1 - 7.7e-05 22.2 2.5 0.43 10.4 0.1 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 AEO55577.1 - 0.0032 18.1 0.2 0.0032 18.1 0.1 2.9 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 AEO55577.1 - 0.037 14.6 5.4 0.23 12.2 0.0 4.0 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 AEO55577.1 - 0.052 13.9 2.2 0.055 13.8 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat ATG27 PF09451.5 AEO55577.1 - 0.063 12.5 0.1 0.099 11.8 0.1 1.2 1 0 0 1 1 1 0 Autophagy-related protein 27 TPR_17 PF13431.1 AEO55577.1 - 0.092 12.9 0.3 9.4 6.7 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.13 AEO55577.1 - 0.72 9.7 7.2 0.4 10.5 0.3 3.3 2 2 2 4 4 4 0 MIT (microtubule interacting and transport) domain HAD_2 PF13419.1 AEO55578.1 - 1.2e-12 48.4 0.0 2.1e-05 24.8 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 AEO55578.1 - 0.00018 21.1 0.0 0.00031 20.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 AEO55578.1 - 0.00035 21.0 0.0 0.039 14.3 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Fungal_trans_2 PF11951.3 AEO55579.1 - 3.5e-07 29.1 1.8 7.6e-05 21.4 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain WD40 PF00400.27 AEO55580.1 - 4.6e-18 64.3 4.1 0.0057 16.4 0.0 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat PQQ_3 PF13570.1 AEO55580.1 - 0.024 14.9 0.0 9.7 6.6 0.0 2.8 2 0 0 2 2 2 0 PQQ-like domain Acyltransferase PF01553.16 AEO55581.1 - 4.2e-14 52.1 0.0 1.1e-13 50.7 0.0 1.7 1 1 0 1 1 1 1 Acyltransferase HTH_Crp_2 PF13545.1 AEO55581.1 - 0.054 13.2 0.0 0.75 9.6 0.0 2.5 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain UPF0086 PF01868.11 AEO55583.1 - 4.4e-25 87.1 0.1 6.9e-25 86.5 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Milton PF12448.3 AEO55583.1 - 0.087 13.0 2.7 0.17 12.0 1.9 1.4 1 0 0 1 1 1 0 Kinesin associated protein Pantoate_ligase PF02569.10 AEO55584.1 - 1.6e-81 273.1 0.0 3e-81 272.2 0.0 1.4 1 1 0 1 1 1 1 Pantoate-beta-alanine ligase Peptidase_S10 PF00450.17 AEO55585.1 - 6.8e-56 190.1 0.0 8.8e-56 189.8 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase DUF1772 PF08592.6 AEO55588.1 - 5.8e-06 26.0 0.4 0.00081 19.1 0.5 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF1772) PUA PF01472.15 AEO55589.1 - 1.4e-14 53.5 0.3 3.6e-06 26.6 0.2 2.3 2 0 0 2 2 2 2 PUA domain Inhibitor_I78 PF11720.3 AEO55590.1 - 3e-12 46.0 0.0 3.9e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.13 AEO55590.1 - 6.2e-06 26.2 0.3 1.1e-05 25.5 0.2 1.5 1 1 0 1 1 1 1 Potato inhibitor I family DUF2924 PF11149.3 AEO55590.1 - 0.11 12.4 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) CD99L2 PF12301.3 AEO55591.1 - 8.8 5.9 10.6 18 4.9 7.4 1.7 1 1 0 1 1 1 0 CD99 antigen like protein 2 Shisa PF13908.1 AEO55592.1 - 0.0037 17.4 2.5 0.0037 17.4 1.7 1.8 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator EphA2_TM PF14575.1 AEO55592.1 - 0.027 14.8 0.7 0.05 13.9 0.5 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Ribosomal_60s PF00428.14 AEO55592.1 - 0.088 13.2 0.5 0.088 13.2 0.4 2.9 3 1 0 3 3 3 0 60s Acidic ribosomal protein LRR19-TM PF15176.1 AEO55592.1 - 0.14 11.8 0.1 0.34 10.6 0.1 1.6 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain MFS_2 PF13347.1 AEO55592.1 - 0.15 10.4 0.0 0.15 10.4 0.0 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein Adeno_E3_CR2 PF02439.10 AEO55592.1 - 0.16 11.5 5.3 0.44 10.1 3.7 1.7 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 NST1 PF13945.1 AEO55593.1 - 4.2e-58 196.5 18.4 4.2e-58 196.5 12.7 4.9 2 2 3 5 5 5 1 Salt tolerance down-regulator Ras PF00071.17 AEO55594.1 - 9.6e-46 155.1 0.0 1.1e-45 154.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AEO55594.1 - 8.4e-15 55.3 0.0 1.2e-14 54.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AEO55594.1 - 2.4e-05 23.6 0.0 3.5e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 AEO55594.1 - 0.039 13.1 0.0 0.052 12.7 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 AEO55594.1 - 0.041 13.3 0.1 2.6 7.5 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.1 AEO55594.1 - 0.15 11.9 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain MRP-L28 PF09812.4 AEO55595.1 - 2.3e-10 40.5 0.1 2.7e-10 40.2 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 PDE6_gamma PF04868.7 AEO55595.1 - 0.13 12.1 3.7 0.096 12.5 1.1 1.9 2 1 0 2 2 2 0 Retinal cGMP phosphodiesterase, gamma subunit GATase_5 PF13507.1 AEO55596.1 - 9.4e-98 326.2 0.0 1.4e-97 325.6 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 AEO55596.1 - 4.1e-42 143.7 1.2 7.9e-23 81.1 0.1 2.6 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 AEO55596.1 - 6.5e-24 83.9 0.1 5.3e-23 81.0 0.0 2.5 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain TPR_11 PF13414.1 AEO55597.1 - 8.5e-19 66.9 13.1 4.4e-16 58.2 6.7 2.4 1 1 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 AEO55597.1 - 5.7e-17 60.5 9.9 1.5e-08 33.8 1.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 AEO55597.1 - 1.1e-14 53.0 11.8 1.5e-06 27.6 0.9 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 AEO55597.1 - 1.3e-07 31.2 6.4 0.0014 18.6 0.6 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 AEO55597.1 - 2.3e-07 31.2 9.8 2.3e-07 31.2 6.8 2.9 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 AEO55597.1 - 1.4e-06 28.4 9.3 0.0061 17.0 0.8 3.5 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 AEO55597.1 - 6.8e-06 25.4 2.7 0.013 15.2 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 AEO55597.1 - 1.7e-05 24.6 9.9 0.0062 16.4 0.9 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 AEO55597.1 - 2e-05 24.0 9.4 0.26 11.1 0.5 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat BTAD PF03704.12 AEO55597.1 - 0.00045 20.5 2.2 0.27 11.5 0.3 2.4 1 1 1 2 2 2 2 Bacterial transcriptional activator domain TPR_19 PF14559.1 AEO55597.1 - 0.00045 20.4 5.9 0.001 19.3 3.1 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 AEO55597.1 - 0.0016 18.2 4.6 0.0016 18.2 1.7 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat XPC-binding PF09280.6 AEO55597.1 - 0.0028 17.0 2.4 0.0059 16.0 1.7 1.5 1 0 0 1 1 1 1 XPC-binding domain TPR_10 PF13374.1 AEO55597.1 - 0.0067 16.3 7.3 0.82 9.6 0.4 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 AEO55597.1 - 0.013 15.9 8.0 0.75 10.3 0.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DHHA1 PF02272.14 AEO55597.1 - 10 5.9 8.8 7.8 6.2 0.0 2.9 2 1 0 2 2 2 0 DHHA1 domain RINGv PF12906.2 AEO55598.1 - 1.4e-05 25.0 6.0 2.3e-05 24.3 4.2 1.3 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 AEO55598.1 - 8.2e-05 22.3 5.0 0.00013 21.7 3.5 1.3 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.3 AEO55598.1 - 0.00064 19.6 3.6 0.0011 18.8 2.5 1.3 1 0 0 1 1 1 1 FANCL C-terminal domain Plasmodium_Vir PF05795.6 AEO55598.1 - 0.059 12.5 0.0 0.085 12.0 0.0 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein zf-C3HC4_3 PF13920.1 AEO55598.1 - 0.12 12.0 4.2 0.19 11.4 2.9 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 AEO55598.1 - 0.38 10.9 3.9 0.83 9.7 2.7 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_4 PF14570.1 AEO55598.1 - 0.44 10.1 5.1 0.91 9.1 3.6 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.1 AEO55598.1 - 1.8 8.6 5.2 3.1 7.9 3.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AEO55598.1 - 2.3 7.9 5.6 3.7 7.3 3.9 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) GalKase_gal_bdg PF10509.4 AEO55599.1 - 4.8e-20 70.5 0.0 1.1e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 AEO55599.1 - 1.9e-14 53.4 1.8 6.5e-14 51.7 0.8 2.2 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 AEO55599.1 - 2.9e-12 46.6 0.4 7.9e-12 45.2 0.0 1.9 2 0 0 2 2 2 1 GHMP kinases C terminal MFS_1 PF07690.11 AEO55600.1 - 0.17 10.5 45.3 11 4.6 31.4 3.4 1 1 0 1 1 1 0 Major Facilitator Superfamily TPP_enzyme_N PF02776.13 AEO55601.1 - 4.3e-58 195.5 0.5 5.8e-57 191.9 0.1 2.6 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 AEO55601.1 - 7.2e-51 171.7 0.3 2.7e-49 166.6 0.1 2.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 AEO55601.1 - 1.7e-37 128.2 0.3 9.7e-37 125.7 0.1 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain PBP1_TM PF14812.1 AEO55602.1 - 0.16 12.2 15.1 0.25 11.6 10.5 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Rad54_N PF08658.5 AEO55602.1 - 0.41 10.3 5.0 0.5 10.0 3.4 1.1 1 0 0 1 1 1 0 Rad54 N terminal DUF3659 PF12396.3 AEO55605.1 - 6.4e-16 57.7 4.6 1.2e-11 44.0 0.2 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF3659) DUF3659 PF12396.3 AEO55606.1 - 7.8e-106 345.7 34.7 4e-24 84.0 0.1 5.3 5 0 0 5 5 5 5 Protein of unknown function (DUF3659) GCV_T_C PF08669.6 AEO55606.1 - 0.017 15.1 3.6 13 5.8 0.0 3.9 4 0 0 4 4 4 0 Glycine cleavage T-protein C-terminal barrel domain Transferase PF02458.10 AEO55607.1 - 0.064 11.6 0.0 0.065 11.6 0.0 1.1 1 0 0 1 1 1 0 Transferase family SNF2_N PF00176.18 AEO55608.1 - 2.5e-74 249.7 0.0 4e-74 249.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 AEO55608.1 - 2.1e-13 50.1 0.0 4.5e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 AEO55608.1 - 2.7e-11 43.1 0.0 9.1e-11 41.4 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 AEO55608.1 - 2.1e-08 33.8 16.4 2.1e-08 33.8 11.4 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 AEO55608.1 - 3.6e-08 32.9 15.6 3.4e-07 29.8 9.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AEO55608.1 - 2.1e-07 30.8 21.7 8.5e-07 28.9 12.8 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO55608.1 - 2e-06 27.4 15.4 2e-06 27.4 10.7 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 AEO55608.1 - 1.6e-05 24.4 18.7 1.6e-05 24.4 13.0 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 AEO55608.1 - 0.0002 21.1 16.8 0.00042 20.1 11.7 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 AEO55608.1 - 0.00076 19.5 7.0 0.0022 18.0 4.9 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_6 PF14835.1 AEO55608.1 - 0.012 15.3 7.0 0.035 13.8 4.9 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 AEO55608.1 - 0.031 14.1 6.4 0.07 12.9 4.4 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Rad50_zn_hook PF04423.9 AEO55608.1 - 0.099 12.1 3.3 1.7 8.1 0.1 2.9 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_UBOX PF13445.1 AEO55608.1 - 0.12 12.1 17.6 0.04 13.6 9.6 2.3 2 0 0 2 2 2 0 RING-type zinc-finger Aconitase_C PF00694.14 AEO55608.1 - 0.13 12.3 0.0 0.44 10.6 0.0 1.8 1 0 0 1 1 1 0 Aconitase C-terminal domain zf-P11 PF03854.9 AEO55608.1 - 0.34 10.4 14.6 1 8.8 0.1 2.7 2 1 1 3 3 3 0 P-11 zinc finger Cpn10 PF00166.16 AEO55609.1 - 1.3e-28 98.7 0.0 1.5e-28 98.5 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Pkinase PF00069.20 AEO55610.1 - 6.9e-60 202.3 0.0 1.8e-59 201.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO55610.1 - 4.2e-22 78.4 0.0 9.5e-22 77.2 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 AEO55610.1 - 0.0049 16.6 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Ribosomal_L11 PF00298.14 AEO55611.1 - 2.8e-26 91.4 1.0 6.9e-26 90.1 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.9 AEO55611.1 - 5.2e-26 89.8 0.3 9.1e-26 89.1 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Svf1 PF08622.5 AEO55612.1 - 2.2e-132 440.9 0.0 2.7e-132 440.6 0.0 1.1 1 0 0 1 1 1 1 Svf1-like Histone PF00125.19 AEO55613.1 - 7.8e-11 41.9 0.2 9.8e-11 41.6 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 AEO55613.1 - 0.00083 19.3 0.1 0.0015 18.5 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PCP_red PF08369.5 AEO55613.1 - 0.077 12.8 0.4 0.16 11.8 0.0 1.7 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit Acetyltransf_7 PF13508.1 AEO55614.1 - 0.0067 16.5 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 AEO55614.1 - 0.007 16.3 0.2 0.018 15.0 0.1 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 AEO55614.1 - 0.095 12.5 0.0 1.9 8.3 0.0 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain AOX PF01786.12 AEO55615.1 - 8.5e-86 286.6 0.0 1.1e-85 286.3 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase zf-H2C2_2 PF13465.1 AEO55616.1 - 2.7e-14 52.6 8.3 5.3e-08 32.7 0.2 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 AEO55616.1 - 5.2e-12 45.3 12.0 8.5e-06 25.8 1.6 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AEO55616.1 - 4.5e-11 42.2 11.7 3.2e-05 23.9 1.8 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 AEO55616.1 - 6.5e-07 29.3 2.0 0.074 13.2 0.2 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 AEO55616.1 - 2.9e-05 24.0 1.4 0.0099 16.0 0.2 3.0 3 0 0 3 3 3 1 Zinc-finger of C2H2 type TOH_N PF12549.3 AEO55616.1 - 0.015 14.8 0.1 0.015 14.8 0.1 3.7 4 0 0 4 4 4 0 Tyrosine hydroxylase N terminal zf-Di19 PF05605.7 AEO55616.1 - 0.067 13.3 1.6 0.13 12.4 1.1 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Zn_ribbon_recom PF13408.1 AEO55616.1 - 0.1 12.8 0.8 0.23 11.7 0.6 1.5 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain LIM PF00412.17 AEO55616.1 - 0.44 10.6 3.5 3.2 7.8 2.4 2.1 1 1 1 2 2 2 0 LIM domain zf-C2H2_6 PF13912.1 AEO55616.1 - 0.7 9.8 9.8 4.7 7.2 0.4 3.8 4 0 0 4 4 4 0 C2H2-type zinc finger ADH_zinc_N PF00107.21 AEO55617.1 - 8.7e-09 35.0 0.0 1.6e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AEO55617.1 - 1.8e-08 34.1 0.4 5.5e-08 32.5 0.2 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain MFS_1 PF07690.11 AEO55620.1 - 1.2e-48 165.6 21.1 1.9e-48 164.9 14.7 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO55620.1 - 7e-10 38.0 11.8 7e-10 38.0 8.2 2.3 2 1 1 3 3 3 1 Sugar (and other) transporter DUF1422 PF07226.6 AEO55620.1 - 0.71 9.6 5.2 0.91 9.2 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1422) Syntaxin-18_N PF10496.4 AEO55621.1 - 3.1e-15 55.7 0.9 1.2e-14 53.8 0.0 2.4 2 1 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus YjgP_YjgQ PF03739.9 AEO55621.1 - 0.15 10.7 0.1 0.29 9.8 0.1 1.4 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family DUF4446 PF14584.1 AEO55621.1 - 0.67 9.7 3.8 0.69 9.7 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) FUSC PF04632.7 AEO55621.1 - 2.4 6.4 16.4 5.6 5.2 0.2 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein family Cauli_AT PF03233.8 AEO55621.1 - 3.9 7.1 8.0 0.66 9.6 2.3 1.9 2 0 0 2 2 2 0 Aphid transmission protein DAGK_cat PF00781.19 AEO55622.1 - 5.6e-28 96.9 0.0 8.7e-28 96.3 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Nop52 PF05997.7 AEO55623.1 - 4.6e-45 153.7 0.4 7.4e-41 139.9 0.2 2.1 2 0 0 2 2 2 2 Nucleolar protein,Nop52 Aminotran_1_2 PF00155.16 AEO55624.1 - 1.8e-85 287.1 0.0 2e-85 286.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II NARP1 PF12569.3 AEO55625.1 - 1.5e-207 690.4 18.0 3.1e-204 679.5 7.7 2.2 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_16 PF13432.1 AEO55625.1 - 3.5e-25 88.0 35.2 2.2e-05 24.9 0.0 8.8 9 1 0 9 9 8 5 Tetratricopeptide repeat TPR_19 PF14559.1 AEO55625.1 - 9.8e-22 77.0 24.4 3.7e-05 23.9 0.1 8.0 6 1 1 7 7 7 6 Tetratricopeptide repeat TPR_11 PF13414.1 AEO55625.1 - 4.3e-21 74.3 35.8 3.6e-06 26.5 0.1 8.0 9 1 0 9 9 7 5 TPR repeat TPR_2 PF07719.12 AEO55625.1 - 8.2e-19 65.9 34.5 0.00014 21.5 0.2 11.6 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_14 PF13428.1 AEO55625.1 - 6.6e-17 60.4 32.7 0.00025 21.4 0.0 11.5 9 4 3 12 12 11 4 Tetratricopeptide repeat TPR_9 PF13371.1 AEO55625.1 - 2.4e-12 46.5 14.6 0.002 17.9 0.0 7.7 5 3 2 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.23 AEO55625.1 - 6.1e-12 44.6 35.2 8.5e-06 25.1 0.2 10.5 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_17 PF13431.1 AEO55625.1 - 8.7e-11 41.1 24.4 0.00083 19.3 0.0 9.0 12 0 0 12 12 9 3 Tetratricopeptide repeat TPR_12 PF13424.1 AEO55625.1 - 2.8e-10 40.0 27.6 0.0055 16.6 0.1 8.5 6 2 3 9 9 9 2 Tetratricopeptide repeat TPR_8 PF13181.1 AEO55625.1 - 5.8e-08 31.9 19.0 0.0045 16.6 0.1 9.5 10 0 0 10 10 10 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 AEO55625.1 - 1.1e-06 28.4 4.0 2 8.3 0.1 5.7 6 0 0 6 6 5 2 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.1 AEO55625.1 - 4.3e-05 23.2 17.8 0.21 11.5 0.0 7.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.1 AEO55625.1 - 7e-05 22.3 17.0 4 7.4 0.0 9.0 8 1 1 9 9 9 1 Tetratricopeptide repeat TPR_3 PF07720.7 AEO55625.1 - 0.00047 19.8 3.4 0.27 11.0 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat Mgr1 PF08602.5 AEO55625.1 - 0.013 14.5 0.3 0.033 13.1 0.2 1.6 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit PPTA PF01239.17 AEO55625.1 - 0.06 12.7 0.4 22 4.6 0.0 3.7 3 0 0 3 3 3 0 Protein prenyltransferase alpha subunit repeat TPR_4 PF07721.9 AEO55625.1 - 0.25 11.9 16.2 8.4 7.1 0.1 6.7 7 0 0 7 7 6 0 Tetratricopeptide repeat Sec62 PF03839.11 AEO55625.1 - 0.85 8.9 4.0 0.2 11.0 0.5 1.7 2 0 0 2 2 1 0 Translocation protein Sec62 DUF1510 PF07423.6 AEO55625.1 - 1.5 8.1 11.0 3.1 7.1 7.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Alkyl_sulf_dimr PF14863.1 AEO55625.1 - 3 8.0 13.7 2 8.6 0.1 4.0 4 0 0 4 4 3 0 Alkyl sulfatase dimerisation Cid2 PF09774.4 AEO55626.1 - 7.1e-48 162.5 0.0 8.9e-48 162.2 0.0 1.0 1 0 0 1 1 1 1 Caffeine-induced death protein 2 Zn_clus PF00172.13 AEO55627.1 - 9.1e-08 31.8 11.0 1.3e-07 31.3 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BAF1_ABF1 PF04684.8 AEO55627.1 - 6.8 5.4 16.7 11 4.7 11.6 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor 2-Hacid_dh_C PF02826.14 AEO55628.1 - 1.3e-57 193.7 0.0 1.8e-57 193.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 AEO55628.1 - 4.6e-19 68.2 0.0 5.8e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 AEO55628.1 - 3.4e-06 26.9 0.1 6.8e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 AEO55628.1 - 0.097 13.1 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AdoHcyase PF05221.12 AEO55629.1 - 2.3e-141 469.3 0.2 2.7e-141 469.1 0.1 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 AEO55629.1 - 7.5e-84 279.4 2.2 1.3e-83 278.7 1.5 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 AEO55629.1 - 4.3e-05 22.7 0.1 9.4e-05 21.6 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 AEO55629.1 - 0.00069 19.0 0.2 0.0013 18.1 0.2 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain ig PF00047.20 AEO55629.1 - 0.012 15.7 0.0 1.7 8.8 0.0 2.6 2 0 0 2 2 2 0 Immunoglobulin domain TMEM107 PF14995.1 AEO55629.1 - 0.023 14.8 0.0 0.042 13.9 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein TrkA_N PF02254.13 AEO55629.1 - 0.049 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain ELFV_dehydrog PF00208.16 AEO55629.1 - 0.057 12.9 0.9 0.093 12.2 0.2 1.8 2 1 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase JAB PF01398.16 AEO55630.1 - 1.4e-07 31.2 0.3 4.9e-06 26.2 0.2 2.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease TauD PF02668.11 AEO55632.1 - 7.6e-41 140.4 0.0 9.1e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.11 AEO55633.1 - 3.3e-16 58.9 18.0 4.7e-16 58.4 12.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF308 PF03729.8 AEO55633.1 - 0.53 10.3 11.6 0.13 12.2 3.6 2.9 3 0 0 3 3 3 0 Short repeat of unknown function (DUF308) Rib_5-P_isom_A PF06026.9 AEO55634.1 - 1.1e-40 138.8 0.0 9.1e-38 129.2 0.0 2.1 2 0 0 2 2 2 2 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 AEO55634.1 - 0.12 11.9 0.0 5.1 6.7 0.0 2.2 2 0 0 2 2 2 0 DeoR C terminal sensor domain Fungal_trans PF04082.13 AEO55635.1 - 1.4e-11 43.8 0.1 2.3e-11 43.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO55635.1 - 1.3e-05 25.0 7.7 2.2e-05 24.2 5.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PKD_channel PF08016.7 AEO55636.1 - 0.002 16.6 19.6 0.06 11.7 12.9 2.5 1 1 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.26 AEO55636.1 - 0.0036 16.5 25.2 0.041 13.1 14.2 2.7 2 1 0 2 2 2 1 Ion transport protein AAA PF00004.24 AEO55637.1 - 2.2e-15 57.0 0.0 7.6e-15 55.2 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 AEO55637.1 - 0.00013 21.6 0.0 0.00032 20.3 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 AEO55637.1 - 0.0041 17.2 1.1 0.061 13.4 0.2 2.5 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 AEO55637.1 - 0.011 15.4 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 AEO55637.1 - 0.022 14.7 0.3 0.11 12.4 0.2 2.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.1 AEO55637.1 - 0.025 14.8 0.9 0.095 13.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 AEO55637.1 - 0.036 14.8 0.0 0.036 14.8 0.0 3.1 4 1 0 4 4 4 0 AAA domain AAA_11 PF13086.1 AEO55637.1 - 0.13 11.8 6.8 0.15 11.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain vMSA PF00695.14 AEO55637.1 - 2.6 7.1 4.2 5.7 6.0 2.9 1.5 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Methyltransf_10 PF05971.7 AEO55638.1 - 9.6e-64 215.3 0.0 1.4e-63 214.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF890) Methyltransf_26 PF13659.1 AEO55638.1 - 3.1e-06 27.1 0.0 9.1e-06 25.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO55638.1 - 7.6e-05 23.2 0.0 0.00019 21.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AEO55638.1 - 0.00046 19.5 0.0 0.00083 18.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 AEO55638.1 - 0.02 14.0 0.0 0.032 13.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.11 AEO55638.1 - 0.16 11.5 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein XAP5 PF04921.9 AEO55639.1 - 4.5e-85 285.0 0.0 1e-84 283.8 0.0 1.6 1 1 0 1 1 1 1 XAP5, circadian clock regulator eIF-3c_N PF05470.7 AEO55639.1 - 8.1 4.3 10.9 11 3.9 7.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus NAD_binding_10 PF13460.1 AEO55641.1 - 1.9e-07 31.2 0.0 2.5e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 AEO55641.1 - 0.009 14.9 0.1 0.053 12.4 0.0 2.1 1 1 2 3 3 3 1 Male sterility protein Epimerase PF01370.16 AEO55641.1 - 0.093 12.1 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NPV_P10 PF05531.7 AEO55642.1 - 1 9.6 5.8 21 5.4 0.0 3.8 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein LrgB PF04172.11 AEO55643.1 - 3.9e-08 32.7 9.4 4e-05 22.8 0.8 3.3 4 0 0 4 4 4 2 LrgB-like family Rotamase PF00639.16 AEO55644.1 - 4.7e-24 84.9 0.0 6.2e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 AEO55644.1 - 6.3e-17 61.9 0.0 7.8e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 AEO55644.1 - 8.8e-08 31.8 0.5 1.8e-07 30.9 0.3 1.5 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.1 AEO55644.1 - 3.6e-05 24.3 0.0 5.2e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain Ribosomal_L14 PF00238.14 AEO55645.1 - 2e-44 150.2 3.2 2.3e-44 150.0 2.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e PAS_3 PF08447.6 AEO55645.1 - 0.14 12.3 0.0 0.28 11.2 0.0 1.6 1 1 0 1 1 1 0 PAS fold SET PF00856.23 AEO55646.1 - 1.3e-09 38.5 0.0 2.5e-08 34.3 0.0 2.7 2 0 0 2 2 2 1 SET domain BTB PF00651.26 AEO55647.1 - 2.1e-06 27.7 0.0 7.1e-06 25.9 0.0 1.9 1 1 0 1 1 1 1 BTB/POZ domain Glyco_hydro_2_N PF02837.13 AEO55648.1 - 6.7e-32 110.3 0.1 1.4e-30 106.0 0.0 2.6 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 AEO55648.1 - 1.4e-31 109.4 0.0 2.5e-31 108.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 AEO55648.1 - 1.2e-10 41.7 0.1 2.9e-10 40.5 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.1 AEO55648.1 - 0.00021 21.4 0.8 0.022 15.0 0.0 3.3 3 0 0 3 3 3 1 Beta-galactosidase jelly roll domain Big_1 PF02369.11 AEO55648.1 - 0.0099 15.7 0.0 0.0099 15.7 0.0 2.6 3 0 0 3 3 3 1 Bacterial Ig-like domain (group 1) ACC_central PF08326.7 AEO55649.1 - 2e-258 859.2 0.0 2.5e-258 858.9 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 AEO55649.1 - 6.1e-177 588.8 0.0 8.6e-177 588.3 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 AEO55649.1 - 4.4e-53 179.7 0.0 8.1e-53 178.8 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 AEO55649.1 - 1.5e-23 83.0 0.1 3e-23 82.0 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 AEO55649.1 - 1.6e-21 76.2 0.0 3.9e-19 68.6 0.0 2.8 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 AEO55649.1 - 7.7e-15 54.2 0.1 1.7e-14 53.2 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 AEO55649.1 - 1.7e-11 44.2 0.0 4.3e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 AEO55649.1 - 2.6e-08 33.0 0.0 2.1e-05 23.4 0.0 3.1 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 AEO55649.1 - 3.6e-05 23.2 0.0 7.2e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 AEO55649.1 - 0.00071 19.4 0.0 0.0019 18.1 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 AEO55649.1 - 0.0028 17.0 0.0 0.0064 15.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain NUDE_C PF04880.8 AEO55650.1 - 9.4e-15 55.3 20.0 9.4e-15 55.3 13.8 4.2 1 1 2 3 3 2 1 NUDE protein, C-terminal conserved region DUF904 PF06005.7 AEO55650.1 - 0.001 19.3 9.4 0.001 19.3 6.5 3.8 2 1 2 4 4 4 1 Protein of unknown function (DUF904) IncA PF04156.9 AEO55650.1 - 0.029 13.9 33.0 0.061 12.9 14.3 2.7 2 1 1 3 3 3 0 IncA protein WEMBL PF05701.6 AEO55650.1 - 0.14 10.6 29.4 0.21 9.9 20.4 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light ERM PF00769.14 AEO55650.1 - 0.24 10.9 25.0 0.03 13.8 4.9 2.5 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Chibby PF14645.1 AEO55650.1 - 0.85 9.5 16.9 0.17 11.7 1.0 2.9 2 1 1 3 3 3 0 Chibby family CENP-F_leu_zip PF10473.4 AEO55650.1 - 1.4 8.7 34.3 0.77 9.6 7.4 3.8 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.16 AEO55650.1 - 1.8 7.9 29.8 1.8 7.9 6.9 2.6 2 1 1 3 3 3 0 Intermediate filament protein IFT57 PF10498.4 AEO55650.1 - 4.6 5.8 19.3 0.053 12.2 5.0 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Tropomyosin_1 PF12718.2 AEO55650.1 - 7.4 6.4 36.4 37 4.1 13.4 4.0 2 1 1 3 3 3 0 Tropomyosin like Seryl_tRNA_N PF02403.17 AEO55650.1 - 7.4 6.6 25.5 7.9 6.5 6.2 3.4 2 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain ATG16 PF08614.6 AEO55650.1 - 9.5 5.9 29.0 4.4 7.0 5.5 3.4 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) NUDIX PF00293.23 AEO55651.1 - 1.1e-18 67.1 1.2 1.6e-18 66.6 0.3 1.6 2 0 0 2 2 2 1 NUDIX domain Glyco_hydro_61 PF03443.9 AEO55652.1 - 1.5e-60 204.7 0.0 1.7e-60 204.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 AA_permease PF00324.16 AEO55653.1 - 6.6e-104 347.8 40.3 8e-104 347.6 27.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AEO55653.1 - 5.8e-31 107.4 45.1 7e-31 107.2 31.2 1.1 1 0 0 1 1 1 1 Amino acid permease RVT_1 PF00078.22 AEO55654.1 - 0.00019 20.8 0.7 0.00019 20.8 0.5 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 AEO55656.1 - 0.00032 20.4 1.2 0.00045 20.0 0.8 1.2 1 0 0 1 1 1 1 Zinc knuckle DUF1308 PF07000.6 AEO55657.1 - 1.4e-25 89.7 0.0 2.6e-25 88.8 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1308) RLL PF10036.4 AEO55658.1 - 0.6 9.4 7.3 0.74 9.1 5.0 1.1 1 0 0 1 1 1 0 Putative carnitine deficiency-associated protein MAP65_ASE1 PF03999.7 AEO55658.1 - 1.2 7.6 9.3 1.4 7.3 6.4 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF966 PF06136.8 AEO55658.1 - 3.6 6.9 10.9 4.6 6.5 7.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF702 PF05142.7 AEO55658.1 - 5.1 7.2 8.7 3 7.9 4.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF702) SAPS PF04499.10 AEO55658.1 - 7.7 5.0 10.3 9.5 4.7 7.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Na_trans_assoc PF06512.8 AEO55658.1 - 8.6 6.2 13.3 15 5.4 9.2 1.3 1 1 0 1 1 1 0 Sodium ion transport-associated BRF1 PF07741.8 AEO55658.1 - 8.8 6.6 20.8 1.7 8.9 4.9 2.1 2 0 0 2 2 2 0 Brf1-like TBP-binding domain NmrA PF05368.8 AEO55659.1 - 2.1e-33 115.5 0.0 2.7e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 AEO55659.1 - 8.2e-20 71.5 0.1 1.2e-19 71.0 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 AEO55659.1 - 0.00021 20.7 0.1 0.00059 19.3 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 AEO55659.1 - 0.00047 20.1 0.0 0.001 19.0 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.14 AEO55659.1 - 0.0078 14.9 0.0 0.012 14.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 AEO55659.1 - 0.017 15.5 0.4 0.035 14.5 0.3 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.20 AEO55659.1 - 0.026 14.4 0.9 0.047 13.5 0.6 1.4 1 0 0 1 1 1 0 short chain dehydrogenase HEAT_PBS PF03130.11 AEO55659.1 - 0.41 11.2 3.9 28 5.5 0.2 3.5 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat Fungal_trans_2 PF11951.3 AEO55661.1 - 0.0045 15.6 0.0 0.0066 15.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain BTB PF00651.26 AEO55662.1 - 1e-13 51.2 0.1 2.1e-12 47.0 0.0 2.4 3 0 0 3 3 3 1 BTB/POZ domain BTB PF00651.26 AEO55663.1 - 5.4e-13 48.8 0.2 8e-12 45.1 0.1 2.4 3 0 0 3 3 3 1 BTB/POZ domain PolyA_pol PF01743.15 AEO55663.1 - 0.09 12.9 0.1 1.5 9.0 0.0 2.1 2 0 0 2 2 2 0 Poly A polymerase head domain RVT_2 PF07727.9 AEO55664.1 - 9.5e-10 37.8 0.0 9.8e-10 37.8 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HSP20 PF00011.16 AEO55665.1 - 7e-19 67.5 0.0 3.4e-13 49.3 0.0 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family RVT_1 PF00078.22 AEO55666.1 - 1.5e-08 34.2 0.8 1.6e-08 34.1 0.6 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Abhydrolase_6 PF12697.2 AEO55667.1 - 3.1e-30 105.7 8.9 3.8e-30 105.4 6.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO55667.1 - 1.7e-10 40.8 0.8 5.2e-10 39.2 0.6 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO55667.1 - 3e-10 40.0 0.0 0.0035 16.9 0.0 3.1 2 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 AEO55667.1 - 1.2e-05 25.0 0.0 2.5e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase TetR_C_6 PF13977.1 AEO55667.1 - 0.043 13.8 8.3 0.062 13.3 0.9 2.5 2 0 0 2 2 2 0 Bacterial transcriptional repressor ATP_transf PF09830.4 AEO55668.1 - 9e-15 54.2 0.0 1.9e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 ATP adenylyltransferase Complex1_LYR_1 PF13232.1 AEO55668.1 - 0.11 12.7 1.9 1.9 8.7 0.0 2.4 2 0 0 2 2 2 0 Complex1_LYR-like Myb_DNA-bind_6 PF13921.1 AEO55669.1 - 3.9e-06 26.8 0.8 6.6e-06 26.1 0.5 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 AEO55669.1 - 0.0005 20.0 0.5 0.0013 18.7 0.3 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Rap1_C PF11626.3 AEO55669.1 - 0.07 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain EF-1_beta_acid PF10587.4 AEO55671.1 - 0.089 12.9 0.2 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region LEA_6 PF10714.4 AEO55671.1 - 0.77 9.6 4.9 3 7.7 0.3 2.5 2 0 0 2 2 2 0 Late embryogenesis abundant protein 18 Transferase PF02458.10 AEO55672.1 - 0.017 13.6 0.0 0.021 13.2 0.0 1.0 1 0 0 1 1 1 0 Transferase family Catalase PF00199.14 AEO55673.1 - 1e-160 534.6 0.3 1.4e-160 534.1 0.2 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 AEO55673.1 - 1.6e-22 79.1 0.1 3e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 AEO55673.1 - 3.5e-08 33.0 0.1 6e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 AEO55673.1 - 0.00034 19.9 0.1 0.00056 19.2 0.0 1.3 1 0 0 1 1 1 1 Putative amidotransferase Gpi16 PF04113.9 AEO55675.1 - 1.5e-242 805.6 0.0 1.9e-242 805.3 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component LUC7 PF03194.10 AEO55676.1 - 7.4e-70 235.3 0.3 9.2e-70 235.0 0.2 1.0 1 0 0 1 1 1 1 LUC7 N_terminus Occludin_ELL PF07303.8 AEO55676.1 - 0.023 15.3 1.5 0.11 13.2 0.2 2.3 2 0 0 2 2 2 0 Occludin homology domain DUF1241 PF06840.6 AEO55676.1 - 0.03 13.5 0.1 0.23 10.6 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1241) zf-C4H2 PF10146.4 AEO55676.1 - 0.059 13.3 1.7 0.081 12.9 1.2 1.3 1 1 0 1 1 1 0 Zinc finger-containing protein EF1G PF00647.14 AEO55676.1 - 0.1 12.3 0.0 1.1 9.0 0.0 2.1 2 0 0 2 2 2 0 Elongation factor 1 gamma, conserved domain HR1 PF02185.11 AEO55676.1 - 0.12 12.1 1.1 0.24 11.1 0.2 2.0 2 0 0 2 2 2 0 Hr1 repeat Tropomyosin_1 PF12718.2 AEO55676.1 - 0.8 9.5 6.3 2.6 7.8 4.3 1.7 1 1 0 1 1 1 0 Tropomyosin like DUF1682 PF07946.9 AEO55677.1 - 0.54 9.0 7.4 0.78 8.5 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) GMC_oxred_N PF00732.14 AEO55678.1 - 3e-46 157.9 0.0 5.8e-46 156.9 0.0 1.4 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 AEO55678.1 - 1.9e-31 109.3 0.0 3.4e-31 108.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 AEO55678.1 - 0.0012 17.8 0.0 0.0033 16.4 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AEO55678.1 - 0.0021 18.0 0.1 0.0064 16.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 AEO55678.1 - 0.0052 15.7 0.0 0.0085 15.0 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 AEO55678.1 - 0.051 13.3 0.0 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 AEO55678.1 - 0.054 12.1 0.0 0.077 11.6 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_2 PF00890.19 AEO55678.1 - 0.063 12.1 0.0 0.11 11.2 0.0 1.7 1 1 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 AEO55678.1 - 0.072 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 AEO55678.1 - 0.1 12.4 0.0 1.8 8.3 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Chitin_bind_3 PF03067.10 AEO55680.1 - 0.0055 16.9 0.0 0.0091 16.2 0.0 1.3 1 0 0 1 1 1 1 Chitin binding domain E1_DerP2_DerF2 PF02221.10 AEO55680.1 - 0.06 13.5 0.1 0.097 12.9 0.1 1.3 1 0 0 1 1 1 0 ML domain GFO_IDH_MocA PF01408.17 AEO55681.1 - 4.7e-18 65.8 0.1 9e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 AEO55681.1 - 0.00038 20.2 0.0 0.0008 19.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Saccharop_dh PF03435.13 AEO55681.1 - 0.0032 16.4 0.0 0.0046 15.9 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase DAO PF01266.19 AEO55682.1 - 2e-19 69.7 4.6 3.3e-19 69.0 3.2 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AEO55682.1 - 0.0066 16.4 0.2 0.042 13.8 0.0 2.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_Gly3P_dh_N PF01210.18 AEO55682.1 - 0.054 13.2 0.0 0.091 12.4 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus p450 PF00067.17 AEO55683.1 - 4e-57 193.7 0.0 1.4e-56 191.9 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 Epimerase PF01370.16 AEO55684.1 - 0.00034 20.1 0.0 0.00071 19.0 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Terpene_synth_C PF03936.11 AEO55684.1 - 0.00073 18.8 0.0 0.0015 17.8 0.0 1.5 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain adh_short PF00106.20 AEO55684.1 - 0.0088 15.9 0.0 1.7 8.5 0.0 2.6 2 0 0 2 2 2 2 short chain dehydrogenase NAD_binding_4 PF07993.7 AEO55684.1 - 0.048 12.5 0.0 0.59 9.0 0.0 2.4 2 0 0 2 2 2 0 Male sterility protein MFS_1 PF07690.11 AEO55685.1 - 5.6e-26 91.0 36.2 5.6e-26 91.0 25.1 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily DEAD PF00270.24 AEO55687.1 - 4.7e-27 94.5 0.0 8.9e-27 93.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Sec63 PF02889.11 AEO55687.1 - 3.1e-25 89.0 0.0 2.4e-21 76.2 0.0 2.2 1 1 1 2 2 2 2 Sec63 Brl domain Helicase_C PF00271.26 AEO55687.1 - 2.2e-09 37.0 0.0 5.6e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AEO55687.1 - 1.9e-08 34.3 0.0 3.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HHH_5 PF14520.1 AEO55687.1 - 0.0073 16.4 0.0 0.022 14.9 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA_22 PF13401.1 AEO55687.1 - 0.01 15.9 0.0 0.03 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 AEO55687.1 - 0.012 14.5 0.0 0.023 13.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein UvrD-helicase PF00580.16 AEO55687.1 - 0.018 14.3 0.0 0.092 12.0 0.0 2.0 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_30 PF13604.1 AEO55687.1 - 0.028 14.0 0.0 0.06 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 AEO55687.1 - 0.088 12.2 0.0 0.81 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain Exo_endo_phos PF03372.18 AEO55688.1 - 9.7e-11 42.0 0.1 1.4e-10 41.5 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family FAD_binding_3 PF01494.14 AEO55690.1 - 7.3e-21 74.6 0.8 2.5e-19 69.5 0.5 2.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 AEO55690.1 - 0.00052 19.9 0.0 0.0042 17.0 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Nuc_sug_transp PF04142.10 AEO55691.1 - 9.6e-81 270.4 7.5 1.4e-80 269.9 5.2 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 AEO55691.1 - 1.5e-12 47.0 12.3 2.8e-11 42.8 8.4 2.1 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 AEO55691.1 - 3.6e-06 27.0 22.2 3.9e-05 23.7 2.0 2.7 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.11 AEO55691.1 - 0.00011 21.9 21.6 0.0051 16.4 1.1 2.4 2 0 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 AEO55691.1 - 0.00013 22.0 13.0 0.00074 19.6 1.2 2.6 2 0 0 2 2 2 2 Multidrug resistance efflux transporter Pectate_lyase_3 PF12708.2 AEO55693.1 - 1.6e-80 270.4 4.7 2e-65 221.0 0.5 3.1 4 0 0 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 AEO55693.1 - 3.2e-06 26.4 2.0 0.052 13.0 0.1 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase DUF3716 PF12511.3 AEO55694.1 - 1.6e-11 43.6 2.9 2.4e-11 43.0 2.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Lactamase_B PF00753.22 AEO55695.1 - 7.9e-21 74.5 2.8 1.3e-20 73.8 1.9 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 AEO55695.1 - 4.5e-07 29.6 0.0 6.9e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Acetyltransf_2 PF00797.12 AEO55696.1 - 1.7e-44 152.1 0.0 8.5e-44 149.9 0.0 1.8 2 0 0 2 2 2 1 N-acetyltransferase DUF1996 PF09362.5 AEO55698.1 - 9.6e-91 303.6 1.2 1.1e-90 303.3 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DUF1749 PF08538.5 AEO55700.1 - 9.5e-93 310.4 0.0 1.1e-92 310.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 AEO55700.1 - 1.5e-05 25.0 5.4 3.2e-05 23.9 3.7 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO55700.1 - 0.00014 21.6 0.0 0.00021 21.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 AEO55700.1 - 0.0022 17.6 0.0 0.0038 16.8 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF900 PF05990.7 AEO55700.1 - 0.081 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) XPA_C PF05181.7 AEO55700.1 - 0.093 12.3 0.0 0.27 10.8 0.0 1.7 1 0 0 1 1 1 0 XPA protein C-terminus AMP-binding PF00501.23 AEO55701.1 - 2.6e-87 292.9 0.2 7e-83 278.3 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 AEO55701.1 - 8.4e-60 202.1 0.0 6e-33 113.9 0.0 3.9 3 1 0 3 3 3 3 Condensation domain PP-binding PF00550.20 AEO55701.1 - 1.8e-26 92.1 0.1 1.2e-12 47.8 0.0 3.1 3 0 0 3 3 3 2 Phosphopantetheine attachment site ANT PF03374.9 AEO55701.1 - 0.62 10.1 2.5 0.45 10.5 0.2 1.9 2 0 0 2 2 2 0 Phage antirepressor protein KilAC domain ABC_membrane PF00664.18 AEO55702.1 - 2.4e-78 263.3 14.9 1.1e-45 156.1 1.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 AEO55702.1 - 4.6e-62 208.3 0.0 3.3e-31 108.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 AEO55702.1 - 3.4e-13 49.3 0.6 0.0028 16.9 0.0 4.2 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 AEO55702.1 - 5.5e-11 42.9 0.0 0.11 12.4 0.0 4.2 3 1 0 4 4 4 3 AAA domain AAA_16 PF13191.1 AEO55702.1 - 2.6e-10 40.5 2.2 0.00055 19.9 0.6 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 AEO55702.1 - 1.3e-08 34.2 0.2 0.0022 17.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 AEO55702.1 - 8.4e-07 29.8 0.1 0.065 14.0 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 AEO55702.1 - 1.3e-06 28.5 0.3 0.32 11.1 0.0 4.1 3 1 0 3 3 3 2 AAA domain ABC_ATPase PF09818.4 AEO55702.1 - 5.1e-06 25.3 0.1 0.013 14.0 0.0 2.8 3 0 0 3 3 3 2 Predicted ATPase of the ABC class DUF258 PF03193.11 AEO55702.1 - 5.9e-05 22.3 0.0 0.035 13.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 DUF87 PF01935.12 AEO55702.1 - 7.1e-05 22.7 0.6 0.076 12.8 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function DUF87 SbcCD_C PF13558.1 AEO55702.1 - 0.00016 21.5 0.1 0.9 9.4 0.0 3.3 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 AEO55702.1 - 0.00025 20.9 0.3 1.2 9.0 0.0 3.2 4 0 0 4 4 2 2 AAA domain AAA_23 PF13476.1 AEO55702.1 - 0.00027 21.3 0.1 0.91 9.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 AEO55702.1 - 0.00039 19.8 5.7 0.15 11.4 0.0 4.2 3 1 0 3 3 3 1 AAA domain AAA_18 PF13238.1 AEO55702.1 - 0.00061 20.1 0.1 2.1 8.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 AEO55702.1 - 0.0028 16.7 0.0 0.28 10.2 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA PF00004.24 AEO55702.1 - 0.0031 17.7 0.0 32 4.7 0.0 4.2 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.15 AEO55702.1 - 0.004 16.8 0.0 2.5 7.7 0.0 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_5 PF07728.9 AEO55702.1 - 0.0082 15.8 0.3 7.2 6.3 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF3987 PF13148.1 AEO55702.1 - 0.0082 14.7 0.0 3.2 6.2 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3987) Gtr1_RagA PF04670.7 AEO55702.1 - 0.021 13.9 0.0 4.4 6.3 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 AEO55702.1 - 0.024 14.6 0.2 5.4 6.9 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_10 PF12846.2 AEO55702.1 - 0.03 13.7 5.3 1.2 8.5 0.3 3.3 3 1 1 4 4 4 0 AAA-like domain NB-ARC PF00931.17 AEO55702.1 - 0.22 10.3 0.1 17 4.1 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain G-alpha PF00503.15 AEO55702.1 - 0.47 9.0 1.4 8.9 4.8 0.0 2.5 3 0 0 3 3 2 0 G-protein alpha subunit Dicty_REP PF05086.7 AEO55702.1 - 3.9 5.1 6.6 1.7 6.2 2.0 1.9 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein Acetyltransf_8 PF13523.1 AEO55703.1 - 7.9e-35 119.9 0.1 1.1e-34 119.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ECH PF00378.15 AEO55704.1 - 3.5e-50 170.4 0.0 4.4e-50 170.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family MFS_1 PF07690.11 AEO55705.1 - 9.1e-23 80.5 42.8 5.3e-15 54.9 16.1 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 AEO55705.1 - 7.8e-11 40.8 24.9 1.1e-10 40.3 17.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 AEO55705.1 - 0.016 14.9 4.6 1.9 8.3 0.3 3.1 2 0 0 2 2 2 0 MFS_1 like family HEAT PF02985.17 AEO55706.1 - 1.3e-17 62.1 3.4 0.003 17.5 0.0 8.6 9 0 0 9 9 9 3 HEAT repeat HEAT_EZ PF13513.1 AEO55706.1 - 1.4e-16 60.4 19.3 6.6e-06 26.4 0.0 11.4 10 2 4 14 14 14 4 HEAT-like repeat HEAT_2 PF13646.1 AEO55706.1 - 1.3e-15 57.4 23.1 0.00052 20.2 0.1 8.9 3 2 6 10 10 10 5 HEAT repeats Vac14_Fab1_bd PF12755.2 AEO55706.1 - 1.8e-08 34.6 0.1 0.39 11.1 0.0 5.5 4 2 1 5 5 5 2 Vacuolar 14 Fab1-binding region IBN_N PF03810.14 AEO55706.1 - 6.2e-08 32.4 4.0 1.8e-07 30.9 0.3 3.1 3 0 0 3 3 3 1 Importin-beta N-terminal domain RIX1 PF08167.7 AEO55706.1 - 2.2e-06 27.4 0.0 0.039 13.6 0.0 4.2 3 1 1 4 4 4 1 rRNA processing/ribosome biogenesis ParcG PF10274.4 AEO55706.1 - 4.9e-06 26.5 0.3 0.18 11.7 0.0 5.1 5 1 1 6 6 6 1 Parkin co-regulated protein CLASP_N PF12348.3 AEO55706.1 - 4.3e-05 22.9 0.1 0.0017 17.7 0.0 3.4 4 0 0 4 4 4 1 CLASP N terminal Cnd1 PF12717.2 AEO55706.1 - 0.00079 19.3 0.8 5.1 6.9 0.0 4.4 3 2 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 AEO55706.1 - 0.0065 16.2 8.5 14 5.6 0.0 7.3 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat DUF2454 PF10521.4 AEO55706.1 - 0.0068 15.4 0.1 0.35 9.8 0.0 3.7 5 1 0 5 5 5 1 Protein of unknown function (DUF2454) YukD PF08817.5 AEO55706.1 - 0.019 15.5 0.1 1.6 9.3 0.0 3.6 3 0 0 3 3 3 0 WXG100 protein secretion system (Wss), protein YukD DUF2435 PF10363.4 AEO55706.1 - 0.058 13.2 1.4 1.1 9.1 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2435) RTA1 PF04479.8 AEO55707.1 - 7.6e-54 182.5 3.7 1.1e-53 182.0 2.6 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF3671 PF12420.3 AEO55707.1 - 0.45 10.5 2.3 3.8 7.5 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function Tetraspannin PF00335.15 AEO55707.1 - 4.9 6.3 12.5 0.23 10.6 2.1 2.7 1 1 1 2 2 2 0 Tetraspanin family SAICAR_synt PF01259.13 AEO55708.1 - 1.2e-77 260.4 0.0 1.5e-77 260.1 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase Fungal_trans PF04082.13 AEO55709.1 - 0.00012 21.0 0.0 0.00027 19.9 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF3357 PF11837.3 AEO55709.1 - 0.077 12.8 1.4 5.8 6.8 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3357) MFS_1 PF07690.11 AEO55710.1 - 8e-20 70.8 13.1 9.2e-20 70.6 9.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 AEO55710.1 - 4.5e-05 22.0 9.6 0.0011 17.4 6.4 2.4 1 1 1 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.19 AEO55710.1 - 0.00019 20.1 6.4 0.00019 20.1 4.4 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.2 AEO55710.1 - 0.0025 17.5 5.6 0.0025 17.5 3.9 2.1 2 1 1 3 3 3 1 MFS_1 like family YrhC PF14143.1 AEO55710.1 - 8.5 6.4 9.0 14 5.6 0.3 2.9 3 0 0 3 3 3 0 YrhC-like protein AMP-binding PF00501.23 AEO55711.1 - 7.2e-84 281.5 0.0 1.2e-83 280.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 AEO55711.1 - 1.2e-43 149.4 0.0 3e-43 148.1 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 AEO55711.1 - 6.7e-19 67.8 0.4 1.8e-18 66.4 0.3 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Condensation PF00668.15 AEO55711.1 - 5.2e-15 55.0 0.1 7.9e-15 54.4 0.0 1.3 1 0 0 1 1 1 1 Condensation domain AMP-binding_C PF13193.1 AEO55711.1 - 2.2e-06 28.4 0.0 6.8e-06 26.9 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Thiolase_N PF00108.18 AEO55711.1 - 7.4e-05 21.8 0.3 0.00014 20.9 0.2 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.20 AEO55711.1 - 0.00019 21.6 0.1 0.0005 20.2 0.0 1.8 2 0 0 2 2 2 1 Phosphopantetheine attachment site ACP_syn_III PF08545.5 AEO55711.1 - 0.017 14.7 3.7 0.084 12.5 0.5 2.8 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Alpha-amylase PF00128.19 AEO55711.1 - 0.18 11.1 0.0 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 Alpha amylase, catalytic domain 2-Hacid_dh_C PF02826.14 AEO55712.1 - 9.5e-43 145.4 0.0 1.2e-42 145.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 AEO55712.1 - 2e-06 27.3 0.0 3.4e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.1 AEO55712.1 - 0.099 12.9 0.0 0.32 11.3 0.0 1.8 2 0 0 2 2 2 0 XdhC Rossmann domain 7tm_2 PF00002.19 AEO55713.1 - 0.044 12.8 1.5 0.078 12.0 1.1 1.4 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) Methyltransf_2 PF00891.13 AEO55715.1 - 1.2e-27 96.6 0.3 7.9e-27 93.9 0.2 1.9 1 1 0 1 1 1 1 O-methyltransferase PAM2 PF07145.10 AEO55715.1 - 0.14 11.7 0.1 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Ataxin-2 C-terminal region GMC_oxred_N PF00732.14 AEO55716.1 - 2.8e-09 36.5 0.1 3.7e-09 36.1 0.1 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 AEO55716.1 - 2.4e-07 31.1 0.0 3.2e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase tRNA-synt_2 PF00152.15 AEO55717.1 - 2.7e-75 253.2 0.0 4.1e-75 252.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 AEO55717.1 - 1.1e-23 83.4 0.0 1.7e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA_anti-codon PF01336.20 AEO55717.1 - 2.3e-06 27.3 0.0 4.9e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 AEO55717.1 - 0.0093 15.1 0.0 2 7.5 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Abhydrolase_3 PF07859.8 AEO55718.1 - 1e-43 149.3 0.0 1.4e-43 148.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 AEO55718.1 - 3.5e-09 35.9 0.0 5e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 AEO55718.1 - 0.00021 21.0 0.0 0.00041 20.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 AEO55718.1 - 0.084 12.3 0.0 0.61 9.4 0.0 2.2 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase DUF605 PF04652.11 AEO55722.1 - 0.19 11.1 8.1 0.25 10.7 5.6 1.1 1 0 0 1 1 1 0 Vta1 like Ank_2 PF12796.2 AEO55723.1 - 7e-32 109.6 0.0 2e-16 60.0 0.0 3.0 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 AEO55723.1 - 1.2e-31 106.8 6.7 2.1e-10 39.8 0.1 5.6 5 1 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 AEO55723.1 - 4.6e-26 90.2 5.8 8.4e-11 41.7 0.2 4.2 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 AEO55723.1 - 4.1e-25 85.3 2.2 1.7e-07 30.7 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 AEO55723.1 - 2.7e-24 85.0 0.8 2.9e-11 43.5 0.2 4.4 3 1 1 4 4 4 4 Ankyrin repeats (many copies) DNA_RNApol_7kD PF03604.8 AEO55724.1 - 0.12 11.8 1.0 6.7 6.2 0.0 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-CCHC_3 PF13917.1 AEO55724.1 - 0.15 11.8 1.2 0.41 10.4 0.1 1.9 2 0 0 2 2 2 0 Zinc knuckle FeS PF04060.8 AEO55724.1 - 0.34 10.5 4.3 2.3 7.8 0.2 2.2 2 0 0 2 2 2 0 Putative Fe-S cluster Sugar_tr PF00083.19 AEO55726.1 - 1.2e-69 235.0 26.9 1.4e-69 234.8 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO55726.1 - 9.2e-11 41.0 41.1 1.6e-08 33.6 13.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 AEO55726.1 - 0.00023 19.7 7.7 0.00023 19.7 5.3 3.1 2 1 1 3 3 3 2 MFS/sugar transport protein GLE1 PF07817.8 AEO55726.1 - 0.07 12.0 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 GLE1-like protein MFS_1 PF07690.11 AEO55727.1 - 5.3e-05 22.1 26.7 5.3e-05 22.1 18.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily SH3_9 PF14604.1 AEO55728.1 - 1.4e-12 47.0 0.5 3.6e-09 36.0 0.2 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 AEO55728.1 - 0.022 14.2 0.3 0.25 10.8 0.1 2.3 2 0 0 2 2 2 0 Variant SH3 domain SH3_1 PF00018.23 AEO55728.1 - 0.035 13.5 0.1 0.081 12.3 0.1 1.6 1 0 0 1 1 1 0 SH3 domain DUF496 PF04363.7 AEO55728.1 - 0.18 11.6 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF496) GFO_IDH_MocA PF01408.17 AEO55729.1 - 1.8e-16 60.7 0.0 2.9e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold RTA1 PF04479.8 AEO55730.1 - 1.2e-21 77.2 1.4 1.8e-21 76.6 1.0 1.2 1 0 0 1 1 1 1 RTA1 like protein HdeA PF06411.6 AEO55730.1 - 0.13 12.2 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 HdeA/HdeB family Borrelia_P83 PF05262.6 AEO55730.1 - 4.4 5.4 9.5 5.9 5.0 6.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Lactonase PF10282.4 AEO55731.1 - 2.1e-87 293.4 0.0 2.9e-87 292.9 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller MARVEL PF01284.18 AEO55732.1 - 0.0025 17.6 10.2 0.0033 17.2 7.1 1.2 1 0 0 1 1 1 1 Membrane-associating domain SdpI PF13630.1 AEO55732.1 - 0.7 9.6 8.3 11 5.8 0.1 2.4 2 0 0 2 2 2 0 SdpI/YhfL protein family FA_desaturase PF00487.19 AEO55732.1 - 1.6 8.1 11.6 6.4 6.1 0.1 2.1 1 1 1 2 2 2 0 Fatty acid desaturase Amastin PF07344.6 AEO55732.1 - 2.5 7.6 8.1 12 5.5 4.7 2.1 1 1 1 2 2 2 0 Amastin surface glycoprotein DUF4188 PF13826.1 AEO55733.1 - 9.8e-31 106.2 0.0 1.3e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dehydratase_hem PF13816.1 AEO55733.1 - 0.011 14.8 0.0 0.021 13.8 0.0 1.4 1 1 1 2 2 2 0 Haem-containing dehydratase Sugar_tr PF00083.19 AEO55734.1 - 3.8e-81 272.9 16.8 4.3e-81 272.7 11.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO55734.1 - 2.1e-27 95.7 18.3 3e-27 95.2 12.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Tmemb_170 PF10190.4 AEO55734.1 - 0.13 12.3 0.2 0.13 12.3 0.2 2.3 2 0 0 2 2 2 0 Putative transmembrane protein 170 PAN_4 PF14295.1 AEO55735.1 - 4e-05 23.2 0.2 6.9e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 PAN domain F-box PF00646.28 AEO55736.1 - 3.7e-06 26.4 0.0 3.7e-06 26.4 0.0 2.5 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.2 AEO55736.1 - 2.8e-05 23.7 0.1 2.8e-05 23.7 0.1 3.0 3 0 0 3 3 3 1 F-box-like Terminase_GpA PF05876.7 AEO55736.1 - 0.018 13.4 5.2 0.025 12.9 0.3 2.2 2 0 0 2 2 2 0 Phage terminase large subunit (GpA) Octapeptide PF03373.9 AEO55739.1 - 1.7 9.1 0.2 1.7 9.1 0.1 2.7 4 0 0 4 4 4 0 Octapeptide repeat Fungal_trans PF04082.13 AEO55740.1 - 1.4e-11 43.7 0.0 2.7e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO55740.1 - 2.9e-06 27.0 9.6 6.6e-06 25.9 6.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pox_A_type_inc PF04508.7 AEO55740.1 - 0.14 12.0 0.4 0.35 10.7 0.3 1.7 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Totivirus_coat PF05518.6 AEO55742.1 - 0.4 8.4 6.7 0.46 8.2 4.6 1.1 1 0 0 1 1 1 0 Totivirus coat protein zf-CCHC PF00098.18 AEO55743.1 - 1.1e-06 28.3 4.2 1.6e-06 27.7 2.9 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 AEO55743.1 - 0.0033 17.1 3.1 0.0047 16.6 2.1 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 AEO55743.1 - 0.065 12.9 1.8 0.11 12.2 1.2 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.1 AEO55743.1 - 0.13 11.8 3.1 0.3 10.5 2.2 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-LITAF-like PF10601.4 AEO55745.1 - 1.2e-10 41.1 10.8 1.9e-10 40.4 7.5 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Zn-ribbon_8 PF09723.5 AEO55745.1 - 0.013 15.4 0.5 0.88 9.5 0.0 2.5 2 0 0 2 2 2 0 Zinc ribbon domain Ogr_Delta PF04606.7 AEO55745.1 - 0.033 13.8 4.2 2.5 7.8 0.8 2.4 2 1 0 2 2 2 0 Ogr/Delta-like zinc finger Zn_Tnp_IS1 PF03811.8 AEO55745.1 - 0.15 11.5 2.2 0.22 11.0 0.0 2.3 2 0 0 2 2 2 0 InsA N-terminal domain zf-H2C2_2 PF13465.1 AEO55745.1 - 1.4 9.3 0.0 1.4 9.3 0.0 3.0 3 0 0 3 3 3 0 Zinc-finger double domain Pkinase PF00069.20 AEO55746.1 - 1.7e-28 99.5 0.0 2.9e-28 98.7 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO55746.1 - 1.2e-07 31.1 0.0 1.8e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.6 AEO55746.1 - 0.048 12.4 0.1 0.069 11.9 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 AEO55746.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_hydro_16 PF00722.16 AEO55749.1 - 3.5e-13 49.2 0.6 2.2e-12 46.6 0.1 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 HpcH_HpaI PF03328.9 AEO55750.1 - 2.8e-27 95.0 0.0 3.9e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.16 AEO55750.1 - 0.079 11.5 0.0 0.17 10.4 0.0 1.5 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain DNA_pol_viral_N PF00242.12 AEO55751.1 - 3.4 6.5 14.3 4.6 6.1 9.9 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain JSRP PF15312.1 AEO55753.1 - 0.29 11.1 1.7 0.57 10.1 0.0 2.2 2 0 0 2 2 2 0 Junctional sarcoplasmic reticulum protein DUF1264 PF06884.6 AEO55754.1 - 2.7e-71 238.4 0.0 3.3e-71 238.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) AMP-binding PF00501.23 AEO55755.1 - 6.4e-257 851.6 0.0 2.7e-91 306.0 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 AEO55755.1 - 5.8e-173 573.7 0.0 1.5e-33 115.9 0.0 7.6 6 1 0 6 6 6 6 Condensation domain PP-binding PF00550.20 AEO55755.1 - 1.7e-59 198.0 8.7 1.7e-10 40.9 0.2 6.9 6 0 0 6 6 6 6 Phosphopantetheine attachment site AMP-binding_C PF13193.1 AEO55755.1 - 9.7e-15 55.2 4.6 0.00043 21.1 0.0 4.8 5 0 0 5 5 5 3 AMP-binding enzyme C-terminal domain Transferase PF02458.10 AEO55755.1 - 0.0002 19.9 0.0 1.1 7.6 0.0 3.3 3 0 0 3 3 3 2 Transferase family CAT PF00302.13 AEO55755.1 - 0.51 9.9 0.0 15 5.1 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol acetyltransferase DUF229 PF02995.12 AEO55755.1 - 4.8 5.4 0.0 20 3.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF229) K_oxygenase PF13434.1 AEO55757.1 - 5.1e-108 361.0 0.0 6.1e-108 360.7 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 AEO55757.1 - 2.6e-10 40.7 0.0 5e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 AEO55757.1 - 1.4e-09 37.9 0.1 1.1e-08 34.9 0.0 2.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 AEO55757.1 - 0.00061 19.7 0.0 0.0012 18.8 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DUF3040 PF11239.3 AEO55759.1 - 0.013 15.5 0.2 0.02 14.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) IncA PF04156.9 AEO55759.1 - 2.1 7.8 4.4 2.8 7.4 3.1 1.1 1 0 0 1 1 1 0 IncA protein WW PF00397.21 AEO55760.1 - 2.5e-09 36.8 4.8 2.5e-09 36.8 3.4 3.1 3 0 0 3 3 3 1 WW domain FF PF01846.14 AEO55760.1 - 1.1e-07 31.7 0.6 1.1e-07 31.7 0.4 3.3 3 1 0 3 3 3 1 FF domain Maf_N PF08383.6 AEO55760.1 - 0.1 12.1 0.8 0.58 9.7 0.1 2.4 2 0 0 2 2 2 0 Maf N-terminal region Hid1 PF12722.2 AEO55760.1 - 4.4 4.8 7.8 0.45 8.1 0.5 2.0 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein DUF747 PF05346.6 AEO55761.1 - 7.5e-134 445.9 1.8 1e-133 445.5 1.3 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family DLH PF01738.13 AEO55762.1 - 3e-30 105.1 0.0 3.5e-30 104.9 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 AEO55762.1 - 6.2e-07 29.2 0.0 8.7e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Amidohydro_2 PF04909.9 AEO55764.1 - 8.3e-44 150.1 1.0 1.1e-43 149.7 0.7 1.1 1 0 0 1 1 1 1 Amidohydrolase Aldedh PF00171.17 AEO55765.1 - 2.6e-159 530.4 1.2 2.9e-159 530.3 0.9 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 AEO55765.1 - 0.0033 16.6 0.0 0.92 8.6 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) LuxC PF05893.9 AEO55765.1 - 0.0049 15.6 0.0 0.01 14.5 0.0 1.5 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) SMRP1 PF15181.1 AEO55765.1 - 0.074 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Spermatid-specific manchette-related protein 1 FAD_binding_3 PF01494.14 AEO55766.1 - 3.3e-12 46.1 0.0 0.00051 19.1 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain FAD_binding_2 PF00890.19 AEO55766.1 - 6.4e-07 28.5 0.0 1.2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 AEO55766.1 - 1.9e-06 27.7 0.1 6.6e-06 26.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 AEO55766.1 - 3.7e-05 23.0 0.0 0.00035 19.7 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.19 AEO55766.1 - 6.3e-05 22.0 0.6 0.00061 18.7 0.2 2.3 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 AEO55766.1 - 9.6e-05 22.3 0.1 0.00025 20.9 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 AEO55766.1 - 0.00013 20.9 0.0 0.00031 19.7 0.0 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.22 AEO55766.1 - 0.00014 22.1 0.1 0.0027 18.0 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 AEO55766.1 - 0.00018 20.1 0.0 0.00074 18.0 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 AEO55766.1 - 0.0097 15.9 0.3 0.16 11.9 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 AEO55766.1 - 0.02 13.9 0.0 8.9 5.2 0.0 2.8 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Trp_halogenase PF04820.9 AEO55766.1 - 0.046 12.3 0.0 5.7 5.4 0.0 2.3 2 0 0 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.7 AEO55766.1 - 0.085 11.7 0.1 0.87 8.4 0.1 2.1 1 1 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.12 AEO55766.1 - 0.092 11.8 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.16 AEO55766.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain p450 PF00067.17 AEO55767.1 - 3.2e-67 227.0 0.0 4.5e-67 226.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_C32 PF05411.7 AEO55767.1 - 0.065 12.9 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Equine arteritis virus putative proteinase Sugar_tr PF00083.19 AEO55768.1 - 3.4e-78 263.2 22.7 3.9e-78 263.0 15.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO55768.1 - 8e-20 70.8 31.7 1.2e-19 70.3 20.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1129 PF06570.6 AEO55768.1 - 0.017 14.4 1.0 0.017 14.4 0.7 3.0 2 2 1 3 3 3 0 Protein of unknown function (DUF1129) TRI12 PF06609.8 AEO55768.1 - 0.017 13.3 8.5 0.0051 15.0 2.8 1.9 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) p450 PF00067.17 AEO55769.1 - 1.3e-70 238.2 0.0 1.6e-70 237.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RTA1 PF04479.8 AEO55770.1 - 1.1e-55 188.5 15.5 1.1e-55 188.5 10.7 1.4 2 0 0 2 2 2 1 RTA1 like protein DUF1980 PF09323.5 AEO55770.1 - 2.6 7.7 6.9 4.3 7.0 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) DUF2556 PF10831.3 AEO55770.1 - 4.3 7.0 6.5 11 5.7 0.6 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2556) Zn_clus PF00172.13 AEO55771.1 - 6.9e-10 38.6 11.4 1.1e-09 38.0 7.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 AEO55771.1 - 0.00026 19.7 0.0 0.00037 19.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Bac_rhamnosid PF05592.6 AEO55772.1 - 4.2e-29 101.1 0.0 7.4e-24 83.8 0.0 2.4 2 1 0 2 2 2 2 Bacterial alpha-L-rhamnosidase Laminin_G_1 PF00054.18 AEO55772.1 - 0.0052 16.7 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 Laminin G domain DUF1080 PF06439.6 AEO55772.1 - 0.017 14.9 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1080) Laminin_G_2 PF02210.19 AEO55772.1 - 0.077 13.0 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 Laminin G domain Glyco_transf_28 PF03033.15 AEO55773.1 - 0.0015 18.3 0.0 0.002 17.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain RVT_1 PF00078.22 AEO55774.1 - 5.9e-05 22.5 0.0 7.1e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FlgN PF05130.7 AEO55775.1 - 0.0051 17.0 1.4 0.0081 16.4 1.0 1.4 1 0 0 1 1 1 1 FlgN protein APG6 PF04111.7 AEO55775.1 - 0.0056 15.7 0.5 0.0069 15.4 0.3 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 OmpH PF03938.9 AEO55775.1 - 0.036 13.9 0.4 0.047 13.6 0.3 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1599 PF07659.6 AEO55775.1 - 0.086 12.9 2.6 5.7 7.0 0.1 2.3 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1599) DUF1664 PF07889.7 AEO55775.1 - 0.15 11.8 0.3 0.23 11.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Fzo_mitofusin PF04799.8 AEO55775.1 - 0.2 11.0 1.1 0.29 10.5 0.8 1.2 1 0 0 1 1 1 0 fzo-like conserved region DUF724 PF05266.9 AEO55775.1 - 0.22 11.1 3.0 0.61 9.6 2.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF724) CALCOCO1 PF07888.6 AEO55775.1 - 1.5 7.0 9.3 1.9 6.7 6.5 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2852 PF11014.3 AEO55775.1 - 2.5 8.0 6.2 2.6 8.0 3.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) Glyco_hydro_61 PF03443.9 AEO55776.1 - 1.8e-42 145.6 0.0 2.4e-42 145.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 GCOM2 PF15328.1 AEO55778.1 - 0.00076 19.2 2.3 0.004 16.9 1.0 2.0 2 0 0 2 2 2 1 Putative GRINL1B complex locus protein 2 ADIP PF11559.3 AEO55778.1 - 0.0045 16.8 10.5 0.6 9.9 2.1 3.0 3 0 0 3 3 3 2 Afadin- and alpha -actinin-Binding TBPIP PF07106.8 AEO55778.1 - 0.05 13.1 8.2 0.88 9.0 1.9 2.3 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CENP-F_leu_zip PF10473.4 AEO55778.1 - 0.18 11.6 10.0 0.27 11.0 1.3 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3373 PF11853.3 AEO55778.1 - 0.19 10.2 1.8 0.19 10.1 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3373) DUF972 PF06156.8 AEO55778.1 - 0.2 12.0 3.9 4 7.8 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Spc24 PF08286.6 AEO55778.1 - 0.74 9.5 6.3 2.7 7.7 0.0 2.5 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DivIC PF04977.10 AEO55778.1 - 0.82 9.2 13.7 0.42 10.1 4.6 2.4 2 0 0 2 2 2 0 Septum formation initiator IncA PF04156.9 AEO55778.1 - 0.99 8.9 9.9 4.1 6.9 0.3 2.3 2 0 0 2 2 2 0 IncA protein Viral_P18 PF04521.8 AEO55778.1 - 1.2 8.5 6.4 3.2 7.2 0.1 2.5 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein DUF2802 PF10975.3 AEO55778.1 - 2.2 8.1 7.0 1.4 8.6 1.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) DUF3847 PF12958.2 AEO55778.1 - 8.7 6.1 13.4 3.1 7.6 3.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) FlgN PF05130.7 AEO55779.1 - 0.0051 17.0 1.4 0.0081 16.4 1.0 1.4 1 0 0 1 1 1 1 FlgN protein APG6 PF04111.7 AEO55779.1 - 0.0056 15.7 0.5 0.0069 15.4 0.3 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 OmpH PF03938.9 AEO55779.1 - 0.036 13.9 0.4 0.047 13.6 0.3 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1599 PF07659.6 AEO55779.1 - 0.086 12.9 2.6 5.7 7.0 0.1 2.3 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1599) DUF1664 PF07889.7 AEO55779.1 - 0.15 11.8 0.3 0.23 11.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Fzo_mitofusin PF04799.8 AEO55779.1 - 0.2 11.0 1.1 0.29 10.5 0.8 1.2 1 0 0 1 1 1 0 fzo-like conserved region DUF724 PF05266.9 AEO55779.1 - 0.22 11.1 3.0 0.61 9.6 2.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF724) CALCOCO1 PF07888.6 AEO55779.1 - 1.5 7.0 9.3 1.9 6.7 6.5 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2852 PF11014.3 AEO55779.1 - 2.5 8.0 6.2 2.6 8.0 3.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) DUF3574 PF12098.3 AEO55781.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3574) Adap_comp_sub PF00928.16 AEO55782.1 - 7e-91 303.9 0.0 9.2e-91 303.5 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 AEO55782.1 - 1e-08 34.9 0.3 1.7e-08 34.2 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RecU PF03838.9 AEO55782.1 - 0.06 12.8 0.6 3 7.3 0.2 2.3 2 0 0 2 2 2 0 Recombination protein U muHD PF10291.4 AEO55782.1 - 0.11 11.6 0.0 0.47 9.5 0.0 1.8 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain Opi1 PF08618.5 AEO55783.1 - 1.8e-65 221.5 5.1 1.6e-42 145.9 0.3 3.5 1 1 2 3 3 3 3 Transcription factor Opi1 Perilipin PF03036.11 AEO55783.1 - 0.035 12.9 0.8 0.46 9.2 0.1 2.2 2 0 0 2 2 2 0 Perilipin family HAD_2 PF13419.1 AEO55784.1 - 5.3e-06 26.7 0.0 0.093 12.9 0.0 2.9 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 AEO55784.1 - 1.5e-05 24.6 0.0 2.6e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like PLDc_2 PF13091.1 AEO55785.1 - 7.7e-22 77.3 0.0 4.3e-13 49.1 0.0 3.2 2 2 0 2 2 2 2 PLD-like domain PLDc PF00614.17 AEO55785.1 - 0.0024 17.6 0.0 0.66 9.8 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif Regulator_TrmB PF11495.3 AEO55785.1 - 0.023 13.6 0.0 7 5.5 0.0 3.5 4 0 0 4 4 4 0 Archaeal transcriptional regulator TrmB Glyco_hydro_6 PF01341.12 AEO55787.1 - 4.4e-111 371.0 2.4 5.6e-111 370.7 1.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.13 AEO55787.1 - 1.4e-13 50.2 15.3 3.9e-13 48.8 10.6 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain ThuA PF06283.6 AEO55788.1 - 6.2e-60 202.5 0.0 1.1e-59 201.8 0.0 1.4 1 1 0 1 1 1 1 Trehalose utilisation Acetyltransf_6 PF13480.1 AEO55788.1 - 0.016 15.1 0.2 1.7 8.5 0.0 2.4 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Luciferase_3H PF10284.4 AEO55788.1 - 0.032 14.1 0.2 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 Luciferase helical bundle domain MFS_1 PF07690.11 AEO55789.1 - 6.7e-37 127.0 28.1 9.6e-37 126.4 19.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UPF0220 PF05255.6 AEO55789.1 - 0.52 9.5 4.0 2 7.6 2.8 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0220) Bestrophin PF01062.16 AEO55790.1 - 1.1e-45 155.8 1.8 2.2e-43 148.2 1.2 2.1 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DUF2062 PF09835.4 AEO55790.1 - 0.11 12.0 3.3 0.76 9.3 0.2 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) VIT1 PF01988.14 AEO55790.1 - 2.8 7.3 5.3 1.3 8.4 0.0 2.2 2 0 0 2 2 2 0 VIT family DUF536 PF04394.9 AEO55792.1 - 0.08 12.6 0.8 0.12 12.1 0.6 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF536 LMSTEN PF07988.7 AEO55792.1 - 0.22 10.8 2.3 0.36 10.1 0.9 1.8 2 0 0 2 2 2 0 LMSTEN motif Adap_comp_sub PF00928.16 AEO55793.1 - 2.5e-86 289.0 0.0 3.3e-86 288.6 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 AEO55793.1 - 2.9e-05 23.8 0.2 5.2e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1081 PF06448.6 AEO55793.1 - 0.04 13.8 0.1 0.089 12.6 0.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1081) PARP PF00644.15 AEO55796.1 - 2.3e-62 210.0 0.0 4.1e-62 209.2 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 AEO55796.1 - 3e-44 149.9 0.2 4.7e-44 149.2 0.1 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 AEO55796.1 - 2.2e-22 78.8 1.5 5.7e-22 77.4 1.1 1.7 1 0 0 1 1 1 1 WGR domain Zn_clus PF00172.13 AEO55796.1 - 2.1e-14 53.1 26.9 6.9e-08 32.2 5.2 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 AEO55796.1 - 1e-13 50.7 0.1 2e-13 49.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain BRCT PF00533.21 AEO55796.1 - 7.1e-13 48.5 0.0 1.5e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 AEO55796.1 - 5.3e-07 29.4 0.1 1.5e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 twin BRCT domain Serglycin PF04360.7 AEO55796.1 - 0.11 12.2 3.8 0.26 11.0 2.6 1.5 1 0 0 1 1 1 0 Serglycin UvdE PF03851.9 AEO55798.1 - 9.6e-118 392.1 0.0 1.2e-117 391.9 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE DUF2145 PF09916.4 AEO55798.1 - 0.044 13.3 0.0 0.068 12.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2145) GSDH PF07995.6 AEO55799.1 - 1.5e-08 34.1 0.0 2.3e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase SGL PF08450.7 AEO55799.1 - 0.095 12.0 0.2 0.42 9.9 0.0 2.2 2 1 0 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region SRP54 PF00448.17 AEO55800.1 - 1.3e-76 256.4 1.8 4.5e-76 254.6 0.5 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 AEO55800.1 - 1.3e-25 89.6 6.7 1.3e-25 89.6 4.6 3.7 3 1 2 5 5 4 1 Signal peptide binding domain SRP54_N PF02881.14 AEO55800.1 - 1.3e-15 57.1 0.1 3.2e-15 55.9 0.1 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 AEO55800.1 - 2.3e-08 33.7 0.1 6.6e-08 32.2 0.0 1.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 AEO55800.1 - 1.8e-07 31.1 0.1 5.1e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 AEO55800.1 - 6.5e-06 25.8 0.0 1.6e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 AEO55800.1 - 1.1e-05 24.9 0.1 4.1e-05 23.0 0.1 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.1 AEO55800.1 - 5.9e-05 23.8 0.0 0.00013 22.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_31 PF13614.1 AEO55800.1 - 0.00065 19.6 0.0 0.18 11.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.15 AEO55800.1 - 0.0011 18.6 0.0 0.0022 17.6 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_16 PF13191.1 AEO55800.1 - 0.0028 17.6 0.2 0.012 15.5 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 AEO55800.1 - 0.004 17.2 0.0 0.018 15.1 0.0 2.2 2 0 0 2 2 1 1 AAA domain 6PF2K PF01591.13 AEO55800.1 - 0.0043 16.1 0.0 0.0073 15.4 0.0 1.4 1 0 0 1 1 1 1 6-phosphofructo-2-kinase Thymidylate_kin PF02223.12 AEO55800.1 - 0.0061 15.9 0.2 0.027 13.8 0.0 2.1 2 0 0 2 2 2 1 Thymidylate kinase Zeta_toxin PF06414.7 AEO55800.1 - 0.0087 15.1 0.0 0.022 13.8 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin ArgK PF03308.11 AEO55800.1 - 0.01 14.6 4.1 0.01 14.6 0.7 2.3 2 1 0 2 2 2 0 ArgK protein ATP_bind_1 PF03029.12 AEO55800.1 - 0.012 15.1 0.2 0.1 12.1 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein TrwB_AAD_bind PF10412.4 AEO55800.1 - 0.017 13.7 0.0 0.043 12.4 0.0 1.6 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain SRPRB PF09439.5 AEO55800.1 - 0.018 14.2 0.9 4.1 6.5 0.6 3.1 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 AEO55800.1 - 0.02 14.8 0.0 0.15 12.0 0.0 2.3 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA PF00004.24 AEO55800.1 - 0.033 14.3 0.1 0.12 12.5 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 AEO55800.1 - 0.038 14.2 0.1 0.089 13.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 AEO55800.1 - 0.046 13.1 0.1 0.1 12.0 0.1 1.7 1 1 0 1 1 1 0 AAA-like domain AAA_19 PF13245.1 AEO55800.1 - 0.058 13.1 0.0 0.23 11.2 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain AAA_28 PF13521.1 AEO55800.1 - 0.065 13.1 0.2 0.16 11.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain PTPlike_phytase PF14566.1 AEO55800.1 - 0.079 13.0 0.1 1.3 9.0 0.0 2.9 4 0 0 4 4 3 0 Inositol hexakisphosphate Abhydrolase_5 PF12695.2 AEO55800.1 - 0.085 12.6 0.0 0.95 9.2 0.0 2.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family Tropomyosin PF00261.15 AEO55802.1 - 0.019 14.0 5.3 0.052 12.6 3.7 1.7 1 0 0 1 1 1 0 Tropomyosin AAA_13 PF13166.1 AEO55802.1 - 0.18 10.2 0.8 0.29 9.5 0.6 1.2 1 0 0 1 1 1 0 AAA domain CDC45 PF02724.9 AEO55803.1 - 6 4.7 9.6 8.6 4.2 6.6 1.1 1 0 0 1 1 1 0 CDC45-like protein GTP_cyclohydroI PF01227.17 AEO55806.1 - 2.8e-74 248.2 0.6 3.6e-74 247.9 0.4 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 AEO55806.1 - 0.0016 18.3 0.0 0.0028 17.5 0.0 1.3 1 0 0 1 1 1 1 QueF-like protein DegT_DnrJ_EryC1 PF01041.12 AEO55806.1 - 0.11 11.5 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family DUF605 PF04652.11 AEO55806.1 - 8.6 5.6 13.5 11 5.2 9.4 1.1 1 0 0 1 1 1 0 Vta1 like TAFII28 PF04719.9 AEO55807.1 - 3.3e-27 94.0 0.6 2.2e-25 88.2 0.1 2.3 2 0 0 2 2 2 2 hTAFII28-like protein conserved region Ribosomal_60s PF00428.14 AEO55807.1 - 0.014 15.8 0.1 0.014 15.8 0.0 3.6 3 1 1 4 4 4 0 60s Acidic ribosomal protein DUF566 PF04484.7 AEO55807.1 - 1.2 8.5 7.4 1.8 7.9 5.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) MutS_II PF05188.12 AEO55808.1 - 0.11 12.4 0.1 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 MutS domain II DUF566 PF04484.7 AEO55808.1 - 2.5 7.5 9.3 3 7.2 6.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Ribosomal_L27 PF01016.14 AEO55809.1 - 7.1e-23 80.1 0.5 1.2e-22 79.4 0.4 1.4 1 0 0 1 1 1 1 Ribosomal L27 protein DUF3804 PF12707.2 AEO55809.1 - 0.018 14.6 0.0 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3804) IPP-2 PF04979.9 AEO55811.1 - 3e-11 43.7 8.6 7.9e-07 29.3 1.1 2.4 2 0 0 2 2 2 2 Protein phosphatase inhibitor 2 (IPP-2) Sugar_tr PF00083.19 AEO55812.1 - 1.8e-76 257.5 21.0 2.1e-76 257.3 14.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO55812.1 - 1.1e-14 53.9 34.7 2.2e-10 39.7 7.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.13 AEO55813.1 - 1.9e-06 27.6 7.1 4.3e-06 26.5 4.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 AEO55813.1 - 0.018 13.6 0.1 0.032 12.8 0.1 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF706 PF05153.10 AEO55814.1 - 4.9e-123 409.3 0.1 6e-123 409.0 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF706) Phosphonate-bd PF12974.2 AEO55815.1 - 5e-05 22.7 0.0 7.2e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.15 AEO55815.1 - 0.00014 21.1 0.0 0.0011 18.2 0.0 2.3 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1 PF09084.6 AEO55815.1 - 0.013 15.1 0.0 0.12 11.9 0.0 2.5 1 1 0 1 1 1 0 NMT1/THI5 like DUF3834 PF12916.2 AEO55815.1 - 0.097 11.6 0.0 0.23 10.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3834) p450 PF00067.17 AEO55817.1 - 8.8e-21 73.9 0.0 1.1e-20 73.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F_bP_aldolase PF01116.15 AEO55818.1 - 8.9e-97 323.6 0.0 1e-96 323.4 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II DUF829 PF05705.9 AEO55819.1 - 7.3e-68 228.8 0.0 8.5e-68 228.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) 4HBT_3 PF13622.1 AEO55820.1 - 6.7e-24 85.0 0.1 7.4e-24 84.8 0.1 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily p450 PF00067.17 AEO55822.1 - 1.1e-54 185.7 0.0 1.5e-54 185.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Trypan_PARP PF05887.6 AEO55823.1 - 0.84 9.4 16.0 1.1 9.1 11.1 1.2 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Mito_fiss_reg PF05308.6 AEO55823.1 - 2.3 7.5 8.0 2.7 7.3 5.5 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator Totivirus_coat PF05518.6 AEO55823.1 - 9.1 3.9 9.1 11 3.7 6.3 1.0 1 0 0 1 1 1 0 Totivirus coat protein Ribonucleas_3_3 PF14622.1 AEO55825.1 - 4.2e-30 104.3 0.0 8.7e-30 103.3 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 AEO55825.1 - 9.4e-05 22.8 0.0 0.0002 21.7 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease III domain KAT11 PF08214.6 AEO55826.1 - 5.3e-95 318.4 0.0 6.9e-95 318.0 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein SOG2 PF10428.4 AEO55826.1 - 0.064 11.8 2.7 0.1 11.2 1.9 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein SET PF00856.23 AEO55827.1 - 3.7e-12 46.8 0.0 1.8e-11 44.6 0.0 2.0 1 1 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.6 AEO55827.1 - 2.6e-06 27.3 0.1 6.9e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding YqzE PF14038.1 AEO55828.1 - 1.8 8.3 3.8 22 4.9 0.2 2.5 1 1 1 2 2 2 0 YqzE-like protein DUF2183 PF09949.4 AEO55830.1 - 1e-29 102.4 0.0 4.5e-29 100.3 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) RVT_1 PF00078.22 AEO55831.1 - 9.7e-05 21.8 0.9 0.00012 21.5 0.6 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_L23 PF00276.15 AEO55831.1 - 0.091 12.7 1.8 0.096 12.6 1.3 1.2 1 0 0 1 1 1 0 Ribosomal protein L23 DUF680 PF05079.7 AEO55832.1 - 0.17 12.4 0.4 6.8 7.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF680) GST_C_3 PF14497.1 AEO55833.1 - 3.9e-10 40.0 0.0 6.5e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 AEO55833.1 - 4.5e-08 32.9 0.0 7.3e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 AEO55833.1 - 3.5e-05 23.5 0.0 5.9e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 AEO55833.1 - 7.5e-05 22.8 0.0 0.00073 19.6 0.0 2.6 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Sulfate_transp PF00916.15 AEO55834.1 - 2.4e-51 174.4 1.7 4.1e-51 173.6 1.2 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 AEO55834.1 - 2.4e-30 104.0 1.2 2.4e-30 104.0 0.8 3.4 4 0 0 4 4 4 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 AEO55834.1 - 1.2e-08 34.4 0.0 2.4e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 AEO55834.1 - 0.015 15.3 0.0 0.2 11.7 0.0 2.7 2 0 0 2 2 2 0 STAS domain MotB_plug PF13677.1 AEO55834.1 - 0.29 10.4 1.2 0.86 8.9 0.8 1.8 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB ACCA PF03255.9 AEO55837.1 - 0.45 10.0 2.3 0.66 9.5 1.6 1.2 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Whi5 PF08528.6 AEO55838.1 - 0.032 13.8 0.9 0.097 12.3 0.3 2.0 2 0 0 2 2 2 0 Whi5 like Glyco_hydro_31 PF01055.21 AEO55839.1 - 2.5e-173 576.9 0.1 3.2e-173 576.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 AEO55839.1 - 4e-12 45.8 1.7 1.1e-10 41.1 0.8 2.7 2 0 0 2 2 2 1 Galactose mutarotase-like zf-C2H2_4 PF13894.1 AEO55840.1 - 5e-07 29.5 14.3 0.31 11.4 0.3 4.9 4 0 0 4 4 4 3 C2H2-type zinc finger Raptor_N PF14538.1 AEO55840.1 - 0.04 13.7 1.6 0.065 13.0 0.0 2.2 3 0 0 3 3 3 0 Raptor N-terminal CASPase like domain zf-H2C2_2 PF13465.1 AEO55840.1 - 0.14 12.4 8.6 7.6 7.0 0.2 4.1 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2 PF00096.21 AEO55840.1 - 0.19 12.1 23.3 0.73 10.3 0.9 4.6 4 1 0 4 4 4 0 Zinc finger, C2H2 type Fungal_trans_2 PF11951.3 AEO55841.1 - 4.6e-13 48.5 0.0 7.9e-13 47.7 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Patatin PF01734.17 AEO55843.1 - 1.1e-24 87.5 0.0 2.3e-24 86.4 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase DUF4449 PF14613.1 AEO55844.1 - 2.4e-05 24.3 0.1 8.5e-05 22.5 0.1 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4449) DUF1828 PF08861.5 AEO55844.1 - 0.0004 19.9 0.0 0.0072 15.9 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF1828 Tricorn_C1 PF14684.1 AEO55844.1 - 0.0015 18.3 0.3 1.7 8.5 0.1 3.3 2 1 1 3 3 3 2 Tricorn protease C1 domain MARVEL PF01284.18 AEO55845.1 - 3e-10 40.0 6.2 3.4e-10 39.9 4.3 1.0 1 0 0 1 1 1 1 Membrane-associating domain Excalibur PF05901.6 AEO55846.1 - 0.89 9.9 9.1 30 5.0 0.2 4.1 4 0 0 4 4 4 0 Excalibur calcium-binding domain WD40 PF00400.27 AEO55847.1 - 1.9e-29 100.4 11.6 1.8e-07 30.7 0.1 5.7 5 1 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 AEO55847.1 - 0.0033 15.6 0.2 0.83 7.7 0.0 2.9 2 1 1 3 3 3 2 Nucleoporin Nup120/160 TFIIIC_delta PF12657.2 AEO55847.1 - 0.041 13.6 0.1 2.1 8.0 0.0 2.6 2 0 0 2 2 2 0 Transcription factor IIIC subunit delta N-term GP40 PF11025.3 AEO55848.1 - 0.35 10.4 3.9 0.75 9.3 2.7 1.5 1 0 0 1 1 1 0 Glycoprotein GP40 of Cryptosporidium Corona_nucleoca PF00937.13 AEO55848.1 - 4.1 6.2 10.1 6.2 5.6 7.0 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein APG5 PF04106.7 AEO55850.1 - 1.9e-42 144.9 0.0 6.1e-42 143.3 0.0 1.7 1 1 0 1 1 1 1 Autophagy protein Apg5 Yae1_N PF09811.4 AEO55852.1 - 0.0061 16.0 24.0 7 6.2 16.6 2.6 1 1 0 1 1 1 1 Essential protein Yae1, N terminal ORMDL PF04061.9 AEO55853.1 - 1.1e-60 203.1 3.7 1.3e-60 202.8 2.6 1.0 1 0 0 1 1 1 1 ORMDL family zf-CCHC PF00098.18 AEO55854.1 - 0.00061 19.5 1.4 0.00061 19.5 1.0 5.0 5 0 0 5 5 5 3 Zinc knuckle CDC45 PF02724.9 AEO55855.1 - 0.45 8.5 8.2 0.59 8.1 5.7 1.2 1 0 0 1 1 1 0 CDC45-like protein HATPase_c PF02518.21 AEO55856.1 - 6e-29 99.9 0.0 1.8e-28 98.4 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 AEO55856.1 - 9.7e-28 96.4 0.1 1.8e-27 95.5 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 AEO55856.1 - 1.1e-13 50.9 0.0 2.4e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.20 AEO55856.1 - 2.8e-05 24.2 1.7 0.22 11.7 0.0 3.4 3 0 0 3 3 3 2 HAMP domain GTP_EFTU PF00009.22 AEO55856.1 - 0.12 11.7 0.2 0.31 10.4 0.1 1.6 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain PP2C_C PF07830.8 AEO55856.1 - 0.42 10.7 1.6 20 5.3 0.0 3.2 3 0 0 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain CMD PF02627.15 AEO55857.1 - 1.7e-08 34.1 0.0 1.3e-07 31.3 0.0 2.1 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Pkinase PF00069.20 AEO55859.1 - 2.8e-09 36.5 0.0 3.7e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 AEO55859.1 - 9.6e-09 35.3 0.3 0.00047 19.9 0.0 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 AEO55859.1 - 4e-08 32.5 0.0 5.4e-06 25.6 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 AEO55859.1 - 4.1e-05 23.0 0.0 0.00013 21.3 0.0 1.8 2 1 1 3 3 3 1 RIO1 family Pkinase_Tyr PF07714.12 AEO55859.1 - 0.00075 18.6 0.0 0.0011 18.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pept_tRNA_hydro PF01195.14 AEO55859.1 - 0.011 15.2 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Peptidyl-tRNA hydrolase Aldo_ket_red PF00248.16 AEO55860.1 - 5.2e-08 32.0 0.0 6.9e-08 31.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Clat_adaptor_s PF01217.15 AEO55861.1 - 2.4e-51 173.1 1.2 2.8e-51 172.9 0.8 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Maf1 PF09174.5 AEO55862.1 - 4.3e-63 212.4 0.0 5.7e-63 211.9 0.0 1.2 1 0 0 1 1 1 1 Maf1 regulator DUF1127 PF06568.6 AEO55862.1 - 0.54 9.7 4.8 0.44 9.9 1.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1127) Nop14 PF04147.7 AEO55862.1 - 6.2 4.5 13.1 8.4 4.1 9.1 1.1 1 0 0 1 1 1 0 Nop14-like family PP2C PF00481.16 AEO55863.1 - 2.3e-82 276.2 0.0 3.7e-82 275.5 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 AEO55863.1 - 0.0012 18.2 0.0 0.0029 17.0 0.0 1.7 1 0 0 1 1 1 1 Protein phosphatase 2C Methyltransf_16 PF10294.4 AEO55864.1 - 2.4e-47 160.6 0.0 2.9e-47 160.3 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 AEO55864.1 - 0.0023 17.3 0.0 0.0035 16.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 AEO55864.1 - 0.0044 16.6 0.0 0.0061 16.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO55864.1 - 0.029 14.3 0.0 0.041 13.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 AEO55864.1 - 0.036 14.6 0.0 0.078 13.5 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain DPBB_1 PF03330.13 AEO55865.1 - 0.0012 18.7 0.1 0.0034 17.3 0.0 1.8 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 AEO55865.1 - 0.11 12.1 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 Barwin family T-box PF00907.17 AEO55865.1 - 0.12 11.8 0.1 0.18 11.2 0.1 1.2 1 0 0 1 1 1 0 T-box DUF605 PF04652.11 AEO55865.1 - 2.8 7.2 14.0 3.2 7.0 9.7 1.1 1 0 0 1 1 1 0 Vta1 like SOG2 PF10428.4 AEO55865.1 - 9.7 4.7 7.8 11 4.5 5.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF1712 PF08217.6 AEO55866.1 - 4e-13 48.4 0.0 2.9e-10 39.0 0.0 2.9 3 0 0 3 3 3 3 Fungal domain of unknown function (DUF1712) PPR_2 PF13041.1 AEO55867.1 - 0.00038 20.3 0.0 0.72 9.8 0.0 3.5 3 1 1 4 4 4 2 PPR repeat family PPR_3 PF13812.1 AEO55867.1 - 0.0099 16.0 0.2 3.5 8.1 0.0 3.7 3 0 0 3 3 3 1 Pentatricopeptide repeat domain Apolipoprotein PF01442.13 AEO55869.1 - 0.0077 15.7 0.5 0.011 15.2 0.3 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain BChl_A PF02327.12 AEO55869.1 - 0.034 12.7 0.1 0.064 11.8 0.0 1.4 1 1 0 1 1 1 0 Bacteriochlorophyll A protein SLY PF12485.3 AEO55869.1 - 0.093 12.9 1.8 0.12 12.6 1.3 1.1 1 0 0 1 1 1 0 Lymphocyte signaling adaptor protein DUF3584 PF12128.3 AEO55869.1 - 0.22 8.7 4.2 0.26 8.5 2.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) YkyA PF10368.4 AEO55869.1 - 0.59 9.4 5.8 0.77 9.0 4.0 1.1 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein ETRAMP PF09716.5 AEO55869.1 - 5.1 7.1 6.5 22 5.0 1.1 2.4 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) V-ATPase_G PF03179.10 AEO55869.1 - 5.5 7.3 9.7 2.3 8.5 3.6 2.0 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit PRP1_N PF06424.7 AEO55870.1 - 3.1e-49 166.7 7.0 3.1e-49 166.7 4.9 2.2 2 1 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 AEO55870.1 - 8.5e-35 116.0 44.4 0.00083 19.7 0.4 14.5 5 3 9 14 14 14 11 Tetratricopeptide repeat TPR_19 PF14559.1 AEO55870.1 - 2.3e-26 91.9 32.7 1.3e-05 25.4 0.9 9.7 9 1 1 10 10 9 6 Tetratricopeptide repeat TPR_16 PF13432.1 AEO55870.1 - 2.4e-23 82.1 30.1 8.7e-06 26.2 0.5 9.4 5 2 5 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.12 AEO55870.1 - 2.4e-15 55.1 13.8 0.013 15.4 0.0 11.6 11 1 0 11 11 11 3 Tetratricopeptide repeat TPR_11 PF13414.1 AEO55870.1 - 8e-12 44.6 16.7 3.8e-05 23.2 0.1 9.0 5 4 4 10 10 10 1 TPR repeat TPR_8 PF13181.1 AEO55870.1 - 8.8e-10 37.6 0.1 0.017 14.8 0.0 8.1 8 1 1 9 9 8 1 Tetratricopeptide repeat TPR_12 PF13424.1 AEO55870.1 - 5.3e-09 35.9 11.8 0.083 12.8 0.0 8.2 5 3 3 8 8 8 2 Tetratricopeptide repeat NARP1 PF12569.3 AEO55870.1 - 1.5e-08 33.8 13.1 0.0093 14.7 0.0 6.4 4 2 3 7 7 7 2 NMDA receptor-regulated protein 1 TPR_1 PF00515.23 AEO55870.1 - 4.4e-07 29.2 0.8 0.033 13.7 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.1 AEO55870.1 - 8.4e-07 28.3 18.1 0.00046 19.3 2.3 5.3 2 2 2 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 AEO55870.1 - 3.2e-06 26.9 6.6 2 8.8 0.0 9.5 9 1 1 10 10 10 1 Tetratricopeptide repeat Suf PF05843.9 AEO55870.1 - 1.1e-05 25.3 0.1 21 4.6 0.0 5.2 5 0 0 5 5 5 0 Suppressor of forked protein (Suf) TPR_9 PF13371.1 AEO55870.1 - 0.00012 21.9 18.6 0.014 15.1 0.1 7.4 6 4 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 AEO55870.1 - 0.0047 17.3 16.2 48 4.7 0.0 10.1 11 0 0 11 11 10 0 Tetratricopeptide repeat TPR_7 PF13176.1 AEO55870.1 - 0.0048 16.5 0.1 36 4.5 0.0 5.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 AEO55870.1 - 0.0084 16.2 0.4 1.5 9.0 0.0 4.5 5 3 0 5 5 4 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF3808 PF10300.4 AEO55870.1 - 0.098 11.2 0.3 13 4.2 0.0 3.4 1 1 1 3 3 3 0 Protein of unknown function (DUF3808) FUSC_2 PF13515.1 AEO55871.1 - 1.3e-24 86.5 5.5 1.3e-24 86.5 3.8 2.8 2 1 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.7 AEO55871.1 - 8.9e-06 24.4 5.1 8.9e-06 24.4 3.5 3.6 3 1 1 4 4 4 1 Fusaric acid resistance protein family ALMT PF11744.3 AEO55871.1 - 0.0056 15.3 20.9 0.019 13.6 2.6 4.3 4 1 0 4 4 4 2 Aluminium activated malate transporter DUF2421 PF10334.4 AEO55871.1 - 0.0089 15.6 0.0 0.024 14.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) Pkinase PF00069.20 AEO55872.1 - 1.8e-62 210.8 0.0 2.2e-62 210.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO55872.1 - 2.7e-40 138.0 0.0 3.7e-40 137.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO55872.1 - 4.7e-06 25.7 0.0 7.1e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 AEO55872.1 - 0.098 11.4 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.15 AEO55872.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase SH2_2 PF14633.1 AEO55873.1 - 1.8e-85 285.5 0.2 1.8e-85 285.5 0.1 2.6 2 0 0 2 2 2 1 SH2 domain DLD PF14878.1 AEO55873.1 - 3.4e-35 120.6 3.6 3.4e-35 120.6 2.5 4.8 5 1 0 5 5 5 1 Death-like domain of SPT6 HHH_7 PF14635.1 AEO55873.1 - 7.8e-31 106.2 0.0 1.8e-30 105.0 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.1 AEO55873.1 - 1.7e-30 105.5 0.0 1.2e-29 102.8 0.0 2.5 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.1 AEO55873.1 - 7.9e-25 86.8 35.9 7.9e-25 86.8 24.9 6.0 5 1 1 6 6 6 1 Acidic N-terminal SPT6 HTH_44 PF14641.1 AEO55873.1 - 5.2e-17 61.9 0.8 5.2e-17 61.9 0.6 2.8 2 1 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 S1 PF00575.18 AEO55873.1 - 3.2e-06 27.1 0.2 1.1e-05 25.4 0.1 1.9 1 0 0 1 1 1 1 S1 RNA binding domain SH2 PF00017.19 AEO55873.1 - 0.00015 21.5 0.0 0.00049 19.8 0.0 2.0 1 0 0 1 1 1 1 SH2 domain HHH_3 PF12836.2 AEO55873.1 - 0.0014 18.5 0.0 0.0041 17.0 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif Oxysterol_BP PF01237.13 AEO55874.1 - 1.1e-108 362.8 0.0 3.1e-108 361.4 0.0 1.7 2 0 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.1 AEO55874.1 - 3.2e-38 129.6 3.0 1.1e-37 127.9 0.0 2.8 3 0 0 3 3 3 1 Pleckstrin homology domain PH PF00169.24 AEO55874.1 - 9.7e-06 25.7 0.1 0.00021 21.4 0.0 2.6 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 AEO55874.1 - 0.085 13.1 4.5 0.13 12.5 0.9 2.6 2 1 0 2 2 2 0 Pleckstrin homology domain Hydantoinase_B PF02538.9 AEO55875.1 - 3.9e-195 649.0 0.3 4.4e-190 632.3 0.0 2.2 2 0 0 2 2 2 2 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 AEO55875.1 - 1e-94 316.9 0.5 1.8e-94 316.1 0.3 1.4 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 AEO55875.1 - 6.9e-59 198.2 1.5 1.8e-57 193.6 0.0 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Pkinase PF00069.20 AEO55876.1 - 7.5e-77 257.9 0.0 1e-76 257.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO55876.1 - 1.3e-37 129.3 0.0 1.9e-37 128.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 AEO55876.1 - 1e-16 60.8 0.4 2.2e-16 59.7 0.3 1.6 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 AEO55876.1 - 1.3e-05 24.3 0.0 3.6e-05 22.8 0.0 1.6 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 AEO55876.1 - 0.0005 19.4 0.1 0.001 18.4 0.1 1.4 1 0 0 1 1 1 1 RIO1 family YukC PF10140.4 AEO55876.1 - 0.0022 16.6 0.1 0.0035 15.9 0.0 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC APH PF01636.18 AEO55876.1 - 0.017 14.8 0.8 0.34 10.6 0.3 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF92 PF01940.11 AEO55877.1 - 1.6e-69 233.4 1.8 2.2e-69 233.0 1.3 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 CTP_transf_1 PF01148.15 AEO55877.1 - 0.02 14.5 1.9 0.02 14.5 1.3 2.0 2 1 0 2 2 2 0 Cytidylyltransferase family Abi PF02517.11 AEO55877.1 - 0.27 11.3 2.5 13 5.9 0.0 2.7 1 1 1 2 2 2 0 CAAX protease self-immunity LSR PF05624.9 AEO55879.1 - 0.14 11.8 0.3 0.17 11.6 0.2 1.1 1 0 0 1 1 1 0 Lipolysis stimulated receptor (LSR) Cu-oxidase_2 PF07731.9 AEO55880.1 - 2.5e-39 133.9 4.5 8.8e-38 128.9 1.0 2.3 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 AEO55880.1 - 2.1e-24 86.2 0.8 9.8e-24 84.0 0.1 2.1 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 AEO55880.1 - 0.0017 18.0 0.6 2.4 7.9 0.0 3.6 4 0 0 4 4 4 2 Multicopper oxidase ketoacyl-synt PF00109.21 AEO55881.1 - 1.2e-74 251.0 0.0 2.1e-74 250.1 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 AEO55881.1 - 2.3e-48 165.1 0.0 4.9e-48 164.1 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain Thioesterase PF00975.15 AEO55881.1 - 1.7e-42 146.2 0.0 1.5e-41 143.1 0.0 2.4 2 0 0 2 2 2 1 Thioesterase domain Ketoacyl-synt_C PF02801.17 AEO55881.1 - 1.5e-35 121.5 0.2 4.6e-35 120.0 0.1 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 AEO55881.1 - 2.3e-18 66.1 4.8 1e-10 41.6 0.2 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.1 AEO55881.1 - 3.8e-15 55.8 0.0 9.7e-15 54.4 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_6 PF12697.2 AEO55881.1 - 2.4e-06 27.5 0.3 0.0014 18.6 0.0 2.9 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO55881.1 - 4.2e-05 23.3 0.1 0.18 11.5 0.0 2.7 2 0 0 2 2 2 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 AEO55881.1 - 0.00044 19.3 1.9 0.00072 18.6 0.3 2.1 2 1 0 2 2 2 1 Thiolase, N-terminal domain Nuc_rec_co-act PF08815.5 AEO55881.1 - 0.042 13.3 0.0 0.15 11.6 0.0 1.9 1 0 0 1 1 1 0 Nuclear receptor coactivator Borrelia_P83 PF05262.6 AEO55881.1 - 0.7 8.0 10.6 1.3 7.2 7.4 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein Zn_clus PF00172.13 AEO55882.1 - 0.0038 17.0 8.1 0.0077 16.1 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_pol_E_B PF04042.11 AEO55883.1 - 2.5e-68 229.4 0.0 3.6e-68 228.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B TMEM173 PF15009.1 AEO55883.1 - 0.11 11.2 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 173 Glyco_trans_4_4 PF13579.1 AEO55883.1 - 0.13 12.4 5.1 0.28 11.3 1.3 2.6 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain PC4 PF02229.11 AEO55885.1 - 4.9e-21 73.7 0.1 7.4e-21 73.1 0.0 1.3 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) PXA PF02194.10 AEO55886.1 - 1e-36 126.2 0.1 1e-36 126.2 0.1 2.7 2 1 0 2 2 2 1 PXA domain Nexin_C PF08628.7 AEO55886.1 - 2.9e-21 75.6 0.1 2.9e-21 75.6 0.0 2.6 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 AEO55886.1 - 2.6e-09 36.8 0.0 3.8e-08 33.0 0.0 2.5 2 0 0 2 2 2 1 PX domain MFS_1 PF07690.11 AEO55888.1 - 8.5e-32 110.2 22.6 1.2e-31 109.6 15.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily ADIP PF11559.3 AEO55889.1 - 2e-42 144.6 8.5 2e-42 144.6 5.9 2.9 3 0 0 3 3 3 1 Afadin- and alpha -actinin-Binding RRP7 PF12923.2 AEO55890.1 - 4.9e-37 126.8 11.2 4.9e-37 126.8 7.8 2.1 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) RRM_6 PF14259.1 AEO55890.1 - 8e-05 22.5 0.0 0.0086 16.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) MOSC PF03473.12 AEO55891.1 - 7e-17 61.1 0.0 2.7e-16 59.2 0.0 2.0 2 0 0 2 2 2 1 MOSC domain Fer2 PF00111.22 AEO55891.1 - 2.7e-08 33.4 5.5 5.8e-08 32.3 3.8 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.16 AEO55891.1 - 4.1e-05 24.1 0.0 0.00021 21.8 0.0 2.2 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain 3-alpha PF03475.9 AEO55891.1 - 0.025 14.2 0.3 0.047 13.4 0.2 1.5 1 0 0 1 1 1 0 3-alpha domain DHFR_2 PF06442.6 AEO55891.1 - 0.1 12.2 0.1 0.59 9.7 0.0 2.1 2 0 0 2 2 2 0 R67 dihydrofolate reductase NAD_binding_6 PF08030.7 AEO55891.1 - 0.15 11.9 0.0 0.81 9.5 0.0 2.0 2 0 0 2 2 2 0 Ferric reductase NAD binding domain F-box PF00646.28 AEO55892.1 - 3.3e-05 23.4 0.1 8.3e-05 22.1 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 AEO55892.1 - 0.0075 15.9 0.2 0.023 14.3 0.0 1.9 2 0 0 2 2 2 1 F-box-like BAR PF03114.13 AEO55893.1 - 3.1e-66 223.1 5.9 3.7e-66 222.9 4.1 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 AEO55893.1 - 8.2e-15 53.9 0.1 1.5e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 AEO55893.1 - 6e-14 51.3 0.1 9.9e-14 50.6 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 AEO55893.1 - 1.4e-10 40.4 1.8 1.6e-10 40.2 0.0 2.0 3 0 0 3 3 3 1 Variant SH3 domain Vps5 PF09325.5 AEO55893.1 - 0.26 10.5 8.4 11 5.2 4.1 2.4 2 1 0 2 2 2 0 Vps5 C terminal like YlqD PF11068.3 AEO55893.1 - 0.41 10.6 6.5 0.44 10.5 0.0 2.4 2 0 0 2 2 2 0 YlqD protein APG6 PF04111.7 AEO55893.1 - 0.66 8.9 9.0 1.8 7.5 4.3 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 Aminotran_5 PF00266.14 AEO55894.1 - 3e-97 325.6 0.0 3.6e-97 325.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 AEO55894.1 - 4.5e-10 39.1 0.0 7.1e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 AEO55894.1 - 3.2e-07 29.7 0.0 2.1e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 AEO55894.1 - 3.2e-05 22.5 0.1 8.6e-05 21.1 0.0 1.6 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.15 AEO55894.1 - 0.052 11.8 0.0 0.082 11.1 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme A_deaminase PF00962.17 AEO55896.1 - 5.8e-09 35.3 0.0 9e-09 34.6 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase Mito_fiss_reg PF05308.6 AEO55896.1 - 0.023 14.0 1.0 0.023 14.0 0.7 2.0 2 0 0 2 2 2 0 Mitochondrial fission regulator DAO PF01266.19 AEO55897.1 - 1.8e-48 165.2 1.9 2.5e-48 164.7 1.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 AEO55897.1 - 0.00011 22.4 0.0 0.009 16.0 0.0 2.5 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AEO55897.1 - 0.0074 16.2 0.7 0.018 15.0 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 AEO55897.1 - 0.01 14.7 0.0 3.1 6.5 0.0 2.6 2 1 1 3 3 3 0 FAD binding domain FAD_binding_3 PF01494.14 AEO55897.1 - 0.11 11.4 0.1 0.18 10.7 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain eIF-5_eIF-2B PF01873.12 AEO55898.1 - 3.1e-44 149.6 0.2 5e-44 148.9 0.2 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Lar_restr_allev PF14354.1 AEO55898.1 - 0.094 13.0 0.1 0.26 11.6 0.1 1.8 1 0 0 1 1 1 0 Restriction alleviation protein Lar DNA_RNApol_7kD PF03604.8 AEO55898.1 - 0.17 11.4 1.2 0.4 10.2 0.8 1.6 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit Arc_trans_TRASH PF08394.5 AEO55898.1 - 3.7 7.7 7.5 2 8.6 0.2 2.6 1 1 1 2 2 2 0 Archaeal TRASH domain MARVEL PF01284.18 AEO55900.1 - 3.4e-23 82.0 15.2 4.2e-23 81.7 10.5 1.0 1 0 0 1 1 1 1 Membrane-associating domain DUF2541 PF10807.3 AEO55900.1 - 0.047 13.4 0.0 0.1 12.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2541) DUF2755 PF10954.3 AEO55900.1 - 0.58 9.8 3.5 0.39 10.4 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2755) Neurokinin_B PF03823.9 AEO55900.1 - 0.72 9.6 0.1 0.72 9.6 0.1 2.3 3 0 0 3 3 3 0 Neurokinin B PNGaseA PF12222.3 AEO55901.1 - 1.4e-137 459.1 1.6 1.6e-137 458.8 1.1 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A DUF1279 PF06916.8 AEO55902.1 - 2.9e-29 101.1 0.0 6.4e-29 100.1 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) DUF3708 PF12501.3 AEO55902.1 - 0.068 13.0 0.0 4.6 7.0 0.0 2.1 2 0 0 2 2 2 0 Phosphate ATP-binding cassette transporter AIM24 PF01987.12 AEO55903.1 - 7.5e-53 179.1 0.1 9.2e-53 178.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 F-box-like PF12937.2 AEO55905.1 - 4.1e-09 36.0 0.3 1.2e-08 34.5 0.2 1.9 1 0 0 1 1 1 1 F-box-like TPR_11 PF13414.1 AEO55905.1 - 8.8e-07 28.4 0.6 0.0017 17.9 0.0 2.8 2 1 1 3 3 3 2 TPR repeat F-box PF00646.28 AEO55905.1 - 1.2e-06 28.0 1.5 3.7e-06 26.4 0.1 2.6 3 0 0 3 3 3 1 F-box domain TPR_2 PF07719.12 AEO55905.1 - 0.0027 17.5 0.1 2.8 8.0 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF3506 PF12014.3 AEO55905.1 - 0.034 13.9 0.0 0.48 10.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3506) TPR_14 PF13428.1 AEO55905.1 - 0.08 13.6 0.5 12 6.8 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 AEO55905.1 - 0.083 13.5 0.9 7.1 7.4 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Caa3_CtaG PF09678.5 AEO55906.1 - 0.0092 14.9 3.2 0.0098 14.8 2.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) Pkinase PF00069.20 AEO55908.1 - 8e-58 195.6 0.0 1.1e-57 195.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO55908.1 - 7.1e-21 74.4 0.3 1.1e-20 73.8 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 AEO55908.1 - 0.0098 15.6 0.0 0.044 13.5 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 AEO55908.1 - 0.12 11.9 0.9 0.22 11.1 0.6 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pex24p PF06398.6 AEO55909.1 - 3.1e-97 325.5 0.0 6.6e-97 324.5 0.0 1.5 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin Spt20 PF12090.3 AEO55909.1 - 0.0081 15.5 0.1 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Spt20 family FimP PF09766.4 AEO55909.1 - 0.029 13.4 4.9 0.043 12.8 3.4 1.2 1 0 0 1 1 1 0 Fms-interacting protein RIC3 PF15361.1 AEO55909.1 - 0.03 14.5 0.8 0.091 13.0 0.6 1.8 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 DUF639 PF04842.7 AEO55909.1 - 0.044 11.9 0.1 0.066 11.3 0.1 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) DUF4557 PF15101.1 AEO55909.1 - 0.06 13.1 4.0 0.097 12.5 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Ctr PF04145.10 AEO55909.1 - 0.15 12.1 1.8 11 6.0 1.0 2.5 2 0 0 2 2 2 0 Ctr copper transporter family PRT_C PF08372.5 AEO55909.1 - 0.18 11.2 1.4 0.65 9.4 0.2 2.0 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal Suf PF05843.9 AEO55909.1 - 0.43 10.2 4.7 0.69 9.5 3.3 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) polyprenyl_synt PF00348.12 AEO55910.1 - 3.6e-64 216.1 0.0 5e-64 215.6 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase Macoilin PF09726.4 AEO55910.1 - 0.61 8.2 13.8 0.93 7.6 9.6 1.2 1 0 0 1 1 1 0 Transmembrane protein Aa_trans PF01490.13 AEO55911.1 - 2.1e-38 131.8 35.2 2.6e-38 131.5 24.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PIG-P PF08510.7 AEO55911.1 - 2 8.0 5.7 1.7 8.2 1.4 2.6 2 0 0 2 2 2 0 PIG-P CDC14 PF08045.6 AEO55912.1 - 1.1e-86 290.2 0.0 1.2e-86 289.9 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component MFS_1 PF07690.11 AEO55914.1 - 2.8e-42 144.6 37.3 2.8e-42 144.6 25.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.15 AEO55914.1 - 0.3 9.0 5.4 0.83 7.6 0.8 3.1 3 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Pinin_SDK_N PF04697.8 AEO55915.1 - 0.02 14.9 1.5 0.027 14.5 1.1 1.3 1 0 0 1 1 1 0 pinin/SDK conserved region Aldedh PF00171.17 AEO55916.1 - 5e-14 51.4 11.6 1.9e-10 39.7 6.0 2.7 2 1 0 2 2 2 2 Aldehyde dehydrogenase family Kinetocho_Slk19 PF12709.2 AEO55917.1 - 8.5e-22 77.0 5.3 8.5e-22 77.0 3.7 4.1 3 1 0 3 3 3 2 Central kinetochore-associated DUF2605 PF10792.4 AEO55917.1 - 0.037 13.7 1.1 0.1 12.3 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2605) FlaC_arch PF05377.6 AEO55917.1 - 0.13 12.1 19.4 0.028 14.3 1.3 4.6 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) KilA-N PF04383.8 AEO55918.1 - 0.00028 20.4 0.0 0.0039 16.7 0.0 2.2 1 1 0 1 1 1 1 KilA-N domain BRCT PF00533.21 AEO55920.1 - 1.2e-05 25.3 0.0 2.5e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 AEO55920.1 - 0.00013 21.7 2.5 0.00024 20.9 0.0 2.5 3 0 0 3 3 3 1 twin BRCT domain AMP-binding PF00501.23 AEO55921.1 - 3.9e-80 269.2 0.0 4.7e-80 269.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 AEO55921.1 - 9.5e-15 55.3 0.3 9.8e-14 52.0 0.0 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain SerH PF06873.6 AEO55922.1 - 0.018 13.6 6.8 0.021 13.4 4.7 1.1 1 0 0 1 1 1 0 Cell surface immobilisation antigen SerH ADH_zinc_N PF00107.21 AEO55923.1 - 5.6e-26 90.6 0.1 1.2e-25 89.5 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 AEO55923.1 - 5.7e-21 75.7 0.0 2.1e-20 73.9 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AEO55923.1 - 2.9e-05 23.7 0.0 0.0005 19.8 0.0 2.4 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DLH PF01738.13 AEO55924.1 - 1.1e-16 60.7 0.0 5.6e-14 51.9 0.0 2.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 AEO55924.1 - 6.9e-08 32.3 0.3 1.2e-07 31.6 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AEO55924.1 - 1.3e-06 28.4 1.4 0.00024 21.0 0.2 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 AEO55924.1 - 0.077 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 AEO55924.1 - 0.11 12.0 0.1 0.58 9.6 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF3824 PF12868.2 AEO55924.1 - 6 7.7 11.1 0.34 11.8 1.0 2.5 3 0 0 3 3 3 0 Domain of unknwon function (DUF3824) MBF1 PF08523.5 AEO55926.1 - 5.6e-22 77.5 0.8 1.1e-21 76.6 0.5 1.5 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 AEO55926.1 - 2.5e-11 43.2 0.0 4.4e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 AEO55926.1 - 2.6e-05 24.3 0.0 4.7e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.2 AEO55926.1 - 0.0009 19.2 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.1 AEO55926.1 - 0.14 11.5 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF1365 PF07103.6 AEO55927.1 - 6.5e-34 117.1 0.0 6.1e-33 113.9 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1365) GFA PF04828.9 AEO55928.1 - 5.6e-22 77.4 0.0 8.8e-22 76.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.1 AEO55928.1 - 0.3 10.8 0.1 0.3 10.8 0.0 2.5 3 0 0 3 3 3 0 Nudix N-terminal zf-dskA_traR PF01258.12 AEO55928.1 - 1.4 8.6 4.5 4.1 7.2 0.0 2.9 3 0 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger INO80_Ies4 PF08193.6 AEO55929.1 - 7.6e-81 271.3 24.4 9.3e-81 271.0 16.9 1.1 1 0 0 1 1 1 1 INO80 complex subunit Ies4 CLTH PF10607.4 AEO55930.1 - 1.6e-34 118.6 0.0 2.4e-34 118.0 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 AEO55930.1 - 9.4e-20 70.9 0.0 1.5e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 SPRY domain LisH PF08513.6 AEO55930.1 - 9.7e-06 25.1 0.0 2e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 LisH GST_C_2 PF13410.1 AEO55931.1 - 0.0026 17.6 0.1 0.0057 16.5 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 AEO55931.1 - 0.0045 17.4 0.0 0.008 16.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF2731 PF10806.3 AEO55931.1 - 0.0045 17.2 0.1 0.011 15.9 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2731) Tom37 PF10568.4 AEO55931.1 - 0.036 14.3 0.0 0.07 13.4 0.0 1.5 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein Phosphoprotein PF00922.12 AEO55933.1 - 0.24 10.5 1.3 0.26 10.4 0.9 1.0 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein adh_short PF00106.20 AEO55934.1 - 2e-20 73.4 0.4 4.1e-19 69.0 0.3 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO55934.1 - 1.4e-19 70.8 0.0 1.1e-18 67.8 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO55934.1 - 1.2e-07 31.5 0.2 2.2e-07 30.7 0.2 1.3 1 0 0 1 1 1 1 KR domain Chitin_synth_1 PF01644.12 AEO55935.1 - 7e-71 237.2 0.0 1e-70 236.7 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 AEO55935.1 - 1.5e-26 91.8 0.1 2.8e-26 90.9 0.1 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 AEO55935.1 - 7.1e-26 90.6 0.2 3.7e-22 78.4 0.0 2.4 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.1 AEO55935.1 - 7.7e-10 38.7 4.5 7.7e-10 38.7 3.1 2.9 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 AEO55935.1 - 6.6e-09 35.8 0.0 1.1e-07 31.8 0.0 2.6 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Ras PF00071.17 AEO55936.1 - 5.7e-33 113.5 0.0 1.1e-32 112.6 0.0 1.5 1 1 0 1 1 1 1 Ras family Miro PF08477.8 AEO55936.1 - 2.6e-07 31.1 0.1 2e-05 25.0 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein Ser_hydrolase PF06821.8 AEO55936.1 - 0.1 12.1 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Mcp5_PH PF12814.2 AEO55938.1 - 1.3e-47 160.7 0.0 2.7e-47 159.7 0.0 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology YkyA PF10368.4 AEO55938.1 - 0.38 10.0 9.2 0.65 9.3 6.4 1.2 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein TPR_MLP1_2 PF07926.7 AEO55938.1 - 2 8.1 20.7 39 3.9 14.0 2.2 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Fmp27_WPPW PF10359.4 AEO55938.1 - 6.9 4.9 8.8 1.4 7.2 3.4 1.7 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain OTU PF02338.14 AEO55939.1 - 1.2e-12 48.5 0.3 1.2e-12 48.5 0.2 3.5 3 1 0 3 3 3 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 AEO55939.1 - 1.2e-05 24.8 0.0 0.00055 19.3 0.0 2.7 3 1 0 3 3 3 1 Peptidase C65 Otubain UQ_con PF00179.21 AEO55940.1 - 4.4e-35 120.1 0.0 5.6e-35 119.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AEO55940.1 - 0.0035 17.1 0.0 0.0047 16.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B IlvN PF07991.7 AEO55941.1 - 1.8e-46 157.5 0.0 2.9e-46 156.8 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 AEO55941.1 - 7.3e-46 155.6 0.0 1.1e-45 155.1 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 AEO55941.1 - 0.046 14.1 0.4 0.13 12.7 0.0 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 AEO55941.1 - 0.07 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase PALP PF00291.20 AEO55942.1 - 3.2e-31 108.6 0.3 4.3e-31 108.2 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DegT_DnrJ_EryC1 PF01041.12 AEO55942.1 - 0.045 12.7 0.4 0.065 12.2 0.3 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family IDO PF01231.13 AEO55943.1 - 2e-36 125.3 0.0 3e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF3678 PF12435.3 AEO55943.1 - 0.08 12.5 4.6 0.19 11.3 3.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) SpoU_methylase PF00588.14 AEO55945.1 - 1.3e-27 96.4 0.0 2e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 AEO55945.1 - 1.4e-07 31.5 0.0 2.8e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding zf-PHD-like PF15446.1 AEO55946.1 - 2.5e-74 248.3 9.3 5.3e-74 247.2 6.5 1.5 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.18 AEO55946.1 - 6.1e-55 186.1 0.0 9.7e-55 185.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AEO55946.1 - 1.5e-14 53.5 0.0 5e-14 51.9 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 AEO55946.1 - 3.8e-07 29.2 0.0 8.9e-07 28.0 0.0 1.6 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.19 AEO55946.1 - 6.1e-06 25.8 7.1 0.00018 21.0 0.9 4.0 4 0 0 4 4 4 1 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.24 AEO55946.1 - 3.8e-05 23.2 4.1 3.8e-05 23.2 2.8 3.5 2 2 1 3 3 3 1 PHD-finger DEAD PF00270.24 AEO55946.1 - 8.2e-05 22.1 0.0 0.00015 21.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 AEO55946.1 - 0.0051 16.6 0.0 0.029 14.1 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 AEO55946.1 - 0.027 14.5 0.0 0.14 12.3 0.0 2.3 1 1 0 1 1 1 0 AAA domain CDK2AP PF09806.4 AEO55947.1 - 2.8 8.1 40.7 1.7 8.8 6.5 3.6 3 0 0 3 3 3 0 Cyclin-dependent kinase 2-associated protein PCI PF01399.22 AEO55948.1 - 0.0011 19.1 0.0 0.0023 18.2 0.0 1.6 1 0 0 1 1 1 1 PCI domain Rep_fac-A_C PF08646.5 AEO55949.1 - 1.4e-56 190.2 4.4 2.6e-54 182.9 1.7 2.4 2 0 0 2 2 2 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 AEO55949.1 - 1.9e-20 72.5 0.0 5e-20 71.1 0.0 1.8 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 AEO55949.1 - 6.8e-19 67.4 2.0 1.2e-12 47.4 0.0 5.1 6 0 0 6 6 6 2 OB-fold nucleic acid binding domain zf-like PF04071.7 AEO55949.1 - 0.019 14.6 1.2 0.047 13.3 0.8 1.6 1 0 0 1 1 1 0 Cysteine-rich small domain DUF3472 PF11958.3 AEO55949.1 - 0.062 13.6 0.7 0.22 11.8 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3472) Amidohydro_2 PF04909.9 AEO55950.1 - 2.1e-22 79.9 0.0 2.3e-22 79.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Cyt-b5 PF00173.23 AEO55952.1 - 2.1e-20 72.2 0.2 2.4e-20 72.1 0.1 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NFRKB_winged PF14465.1 AEO55953.1 - 0.077 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 NFRKB Winged Helix-like SUR7 PF06687.7 AEO55954.1 - 3.7e-37 127.9 14.3 4.4e-37 127.7 9.9 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF3959 PF13105.1 AEO55954.1 - 0.028 13.7 0.3 0.041 13.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) Fig1 PF12351.3 AEO55954.1 - 2 8.2 16.3 0.72 9.7 8.7 1.9 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 DUF485 PF04341.7 AEO55954.1 - 5.3 6.8 15.8 5.5 6.7 0.1 3.0 2 1 2 4 4 4 0 Protein of unknown function, DUF485 CBM_20 PF00686.14 AEO55955.1 - 0.024 14.2 0.1 0.045 13.3 0.1 1.4 1 0 0 1 1 1 0 Starch binding domain HD PF01966.17 AEO55956.1 - 0.00012 22.1 2.1 0.00023 21.1 0.8 2.0 2 1 0 2 2 2 1 HD domain TFIIE_alpha PF02002.12 AEO55956.1 - 0.044 13.2 0.0 0.078 12.4 0.0 1.3 1 0 0 1 1 1 0 TFIIE alpha subunit HDOD PF08668.7 AEO55956.1 - 0.071 12.3 0.1 0.26 10.5 0.0 1.9 1 1 1 2 2 2 0 HDOD domain zf-U1 PF06220.7 AEO55958.1 - 2.6e-19 68.4 4.2 3.4e-19 68.0 2.9 1.2 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 AEO55958.1 - 0.023 14.8 3.8 0.099 12.8 2.7 2.0 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding AKAP95 PF04988.7 AEO55958.1 - 0.033 13.9 0.2 0.035 13.8 0.1 1.0 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) EMP24_GP25L PF01105.19 AEO55959.1 - 1.2e-41 142.4 0.0 1.4e-41 142.1 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4337 PF14235.1 AEO55959.1 - 0.026 14.3 0.0 0.039 13.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) EzrA PF06160.7 AEO55959.1 - 0.069 11.3 0.2 0.09 10.9 0.1 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Sdh5 PF03937.11 AEO55960.1 - 7.1e-20 70.4 0.6 7.1e-20 70.4 0.4 1.6 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase FANCI_S4 PF14678.1 AEO55960.1 - 0.11 11.5 0.3 0.17 11.0 0.2 1.2 1 0 0 1 1 1 0 FANCI solenoid 4 DUF4106 PF13388.1 AEO55960.1 - 0.89 8.4 6.4 1.4 7.7 4.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Pex14_N PF04695.8 AEO55960.1 - 1.8 8.6 9.7 1.8 8.6 4.0 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MIS13 PF08202.6 AEO55961.1 - 5.8e-63 212.7 0.0 8.8e-63 212.1 0.0 1.2 1 0 0 1 1 1 1 Mis12-Mtw1 protein family Aft1_HRA PF11786.3 AEO55962.1 - 1.8e-29 101.7 9.6 1.8e-29 101.7 6.6 3.1 3 1 0 3 3 3 1 Aft1 HRA domain Aft1_HRR PF11787.3 AEO55962.1 - 1.7e-23 83.4 10.0 1.7e-23 83.4 6.9 5.4 3 2 1 4 4 4 1 Aft1 HRR domain Aft1_OSA PF11785.3 AEO55962.1 - 2e-17 63.4 12.8 2e-17 63.4 8.8 6.0 7 1 1 8 8 8 1 Aft1 osmotic stress response (OSM) domain DUF2146 PF10220.4 AEO55962.1 - 2.9 5.7 8.8 4.5 5.1 6.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Fork_head PF00250.13 AEO55964.1 - 1.5e-12 47.3 0.0 3e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 AEO55964.1 - 7.1e-05 22.8 0.0 0.00013 22.0 0.0 1.4 1 0 0 1 1 1 1 FHA domain Adeno_E3_CR2 PF02439.10 AEO55965.1 - 0.079 12.5 0.0 0.079 12.5 0.0 2.0 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 DUF805 PF05656.9 AEO55965.1 - 0.44 10.3 3.7 5.7 6.7 2.4 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF805) DUF4231 PF14015.1 AEO55965.1 - 8.9 6.3 6.2 25 4.9 4.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) SUR7 PF06687.7 AEO55967.1 - 3.9e-24 85.3 4.9 4e-24 85.3 2.8 1.4 1 1 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 AEO55967.1 - 7.9e-05 22.4 3.6 7.9e-05 22.4 2.5 2.0 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 AEO55967.1 - 0.2 11.3 7.6 0.025 14.2 1.7 1.9 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family Retrotrans_gag PF03732.12 AEO55969.1 - 0.026 14.6 0.1 0.057 13.4 0.1 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein zf-CCHC PF00098.18 AEO55970.1 - 7.9e-06 25.5 1.4 1.2e-05 25.0 1.0 1.3 1 0 0 1 1 1 1 Zinc knuckle Cytomega_UL20A PF05984.7 AEO55970.1 - 1.6 8.9 6.8 5.5 7.2 0.4 2.2 1 1 1 2 2 2 0 Cytomegalovirus UL20A protein Poxvirus_B22R PF04395.7 AEO55972.1 - 0.13 11.7 0.1 0.15 11.5 0.1 1.1 1 0 0 1 1 1 0 Poxvirus B22R protein rve PF00665.21 AEO55973.1 - 1.4e-19 70.3 0.3 9.2e-19 67.7 0.1 2.1 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 AEO55973.1 - 2.1e-13 49.7 0.6 6.8e-13 48.0 0.4 2.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 AEO55973.1 - 0.017 14.8 0.1 1.2 8.9 0.0 2.9 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain zf-H2C2 PF09337.5 AEO55973.1 - 0.033 13.6 0.3 0.071 12.5 0.2 1.6 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger Chromo_shadow PF01393.14 AEO55973.1 - 0.085 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Chromo shadow domain FTA2 PF13095.1 AEO55974.1 - 4.8e-34 117.7 0.0 5.7e-34 117.5 0.0 1.1 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Sigma70_r1_2 PF00140.15 AEO55974.1 - 0.0045 16.6 0.1 0.0088 15.6 0.0 1.4 1 0 0 1 1 1 1 Sigma-70 factor, region 1.2 TRP PF06011.7 AEO55980.1 - 1.6e-153 511.4 29.8 1.9e-153 511.1 20.6 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 AEO55980.1 - 1.2e-42 145.2 0.5 1.9e-42 144.6 0.4 1.3 1 0 0 1 1 1 1 ML-like domain VirB3 PF05101.8 AEO55980.1 - 5.7 7.0 10.7 5.8 6.9 0.1 3.4 3 0 0 3 3 3 0 Type IV secretory pathway, VirB3-like protein OppC_N PF12911.2 AEO55980.1 - 7.1 6.0 11.3 2 7.8 0.0 3.7 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C ATP-synt_8 PF00895.15 AEO55980.1 - 8.5 6.6 8.2 1 9.6 0.9 2.8 2 0 0 2 2 2 0 ATP synthase protein 8 DUF3433 PF11915.3 AEO55981.1 - 2.4e-49 165.4 13.5 2.4e-28 98.1 0.5 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) Peptidase_M48 PF01435.13 AEO55982.1 - 2.3e-41 141.7 0.0 3.1e-41 141.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M48 Kelch_2 PF07646.10 AEO55982.1 - 0.13 12.0 0.0 0.43 10.4 0.0 1.9 1 0 0 1 1 1 0 Kelch motif Kelch_6 PF13964.1 AEO55982.1 - 0.14 12.3 0.8 0.45 10.7 0.0 2.3 2 0 0 2 2 2 0 Kelch motif bZIP_1 PF00170.16 AEO55985.1 - 1.4e-07 31.3 6.8 1.4e-07 31.3 4.7 1.6 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 AEO55985.1 - 0.00071 19.3 9.9 0.00071 19.3 6.9 1.8 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 AEO55985.1 - 0.0056 16.9 8.5 0.0056 16.9 5.9 1.5 2 0 0 2 2 2 1 bZIP Maf transcription factor IncA PF04156.9 AEO55985.1 - 0.027 14.0 0.5 0.033 13.8 0.4 1.1 1 0 0 1 1 1 0 IncA protein BCL9 PF11502.3 AEO55985.1 - 0.05 13.1 0.9 0.1 12.1 0.6 1.5 1 0 0 1 1 1 0 B-cell lymphoma 9 protein DUF3391 PF11871.3 AEO55985.1 - 0.085 13.0 1.2 0.11 12.6 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) DUF745 PF05335.8 AEO55985.1 - 0.14 11.6 3.4 0.19 11.2 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) TPR_12 PF13424.1 AEO55986.1 - 5.2e-11 42.3 10.4 8.3e-05 22.4 0.5 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 AEO55986.1 - 3e-09 36.4 8.6 0.0018 17.8 0.4 3.9 3 1 0 3 3 3 3 TPR repeat TPR_1 PF00515.23 AEO55986.1 - 1.6e-08 33.7 6.9 0.038 13.6 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 AEO55986.1 - 3.1e-08 32.8 3.1 0.35 10.7 0.0 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 AEO55986.1 - 3.5e-06 26.5 11.9 0.0021 17.8 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 AEO55986.1 - 0.0006 19.6 6.7 0.0049 16.7 0.0 4.0 5 0 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 AEO55986.1 - 0.00099 19.2 2.4 0.06 13.4 0.0 3.0 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF4234 PF14018.1 AEO55986.1 - 0.0086 15.7 0.6 0.016 14.9 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4234) TPR_8 PF13181.1 AEO55986.1 - 0.026 14.2 6.8 5.4 7.0 0.1 4.2 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 AEO55986.1 - 0.14 12.6 3.5 22 5.8 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.13 AEO55986.1 - 0.29 11.0 4.3 10 6.0 0.0 3.9 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain Cyt-b5 PF00173.23 AEO55987.1 - 5.6e-16 58.1 0.0 6.6e-16 57.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain zf-C2H2_4 PF13894.1 AEO55989.1 - 4.9e-08 32.7 65.6 0.002 18.2 3.2 8.7 9 0 0 9 9 9 5 C2H2-type zinc finger zf-C2H2 PF00096.21 AEO55989.1 - 8.9e-07 28.8 55.7 0.0025 18.0 0.2 7.7 8 0 0 8 8 8 5 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 AEO55989.1 - 0.0061 16.6 30.6 0.022 14.8 0.3 7.0 7 0 0 7 7 7 3 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 AEO55990.1 - 3e-05 24.0 15.6 0.071 13.4 0.2 4.8 4 1 0 4 4 4 2 C2H2-type zinc finger zf-TRAF PF02176.13 AEO55990.1 - 0.0012 19.1 0.6 0.0012 19.1 0.4 2.0 2 0 0 2 2 2 1 TRAF-type zinc finger zf-C2H2 PF00096.21 AEO55990.1 - 0.0033 17.6 13.1 0.14 12.5 0.1 4.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-met PF12874.2 AEO55990.1 - 0.16 12.2 0.6 19 5.5 0.0 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 AEO55990.1 - 0.49 10.5 3.6 16 5.7 0.0 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding RAP1 PF07218.6 AEO55990.1 - 1.4 6.9 6.7 2.1 6.3 4.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PPR_2 PF13041.1 AEO55992.1 - 4.6e-25 87.3 0.0 3.2e-12 46.2 0.0 3.9 2 1 1 3 3 3 3 PPR repeat family PPR_1 PF12854.2 AEO55992.1 - 8.2e-17 60.3 0.0 2.3e-07 30.1 0.0 4.5 4 0 0 4 4 4 3 PPR repeat PPR PF01535.15 AEO55992.1 - 6.2e-16 57.1 0.0 0.00054 19.7 0.0 5.2 5 0 0 5 5 5 3 PPR repeat PPR_3 PF13812.1 AEO55992.1 - 2.8e-15 55.2 0.7 0.00076 19.5 0.0 6.0 6 0 0 6 6 6 3 Pentatricopeptide repeat domain TAF1D PF15333.1 AEO55992.1 - 0.42 10.3 2.7 0.84 9.3 1.9 1.4 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D cwf18 PF08315.7 AEO55993.1 - 5.9e-44 149.6 6.3 5.9e-44 149.6 4.4 2.2 2 1 0 2 2 2 1 cwf18 pre-mRNA splicing factor DUF2057 PF09829.4 AEO55993.1 - 3.2 7.3 8.3 0.12 11.9 0.6 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) zf-CCHC_3 PF13917.1 AEO55994.1 - 1.8e-13 49.9 1.8 5e-13 48.5 1.2 1.8 1 0 0 1 1 1 1 Zinc knuckle SUZ PF12752.2 AEO55995.1 - 7.8e-16 58.3 2.9 7.8e-16 58.3 2.0 3.3 4 0 0 4 4 4 1 SUZ domain R3H PF01424.17 AEO55995.1 - 6.9e-08 32.0 0.1 1.3e-07 31.2 0.1 1.4 1 0 0 1 1 1 1 R3H domain Glyco_transf_8 PF01501.15 AEO55995.1 - 0.32 10.2 0.0 0.5 9.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 8 JAB PF01398.16 AEO55996.1 - 2e-15 56.4 0.0 3.1e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 AEO55996.1 - 1.1e-14 54.4 0.0 1.7e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function DUF1253 PF06862.7 AEO55997.1 - 6.1e-166 552.2 0.1 7.8e-166 551.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) Ribosomal_L17 PF01196.14 AEO55998.1 - 2.3e-31 108.1 0.0 4.2e-31 107.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L17 DUF481 PF04338.7 AEO55999.1 - 0.0008 19.1 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF481 DUF3854 PF12965.2 AEO55999.1 - 0.034 13.7 0.3 0.072 12.7 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3854) HAUS6_N PF14661.1 AEO55999.1 - 1.6 7.9 10.6 1.5 8.0 6.2 1.7 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF883 PF05957.8 AEO55999.1 - 4.1 7.8 20.8 0.37 11.2 5.6 3.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) DivIVA PF05103.8 AEO55999.1 - 6.9 6.7 10.4 2.7 8.0 4.8 2.0 1 1 1 2 2 2 0 DivIVA protein Acyl_transf_3 PF01757.17 AEO56000.1 - 2.8e-12 46.1 0.1 3.2e-12 45.9 0.1 1.1 1 0 0 1 1 1 1 Acyltransferase family ALAD PF00490.16 AEO56001.1 - 4.1e-118 393.9 0.0 5.2e-118 393.6 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Serglycin PF04360.7 AEO56002.1 - 0.49 10.1 5.2 14 5.3 0.1 3.0 3 0 0 3 3 3 0 Serglycin Y_phosphatase3 PF13350.1 AEO56003.1 - 4.1e-31 108.4 0.0 5.4e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 AEO56003.1 - 1.8e-10 40.7 1.0 1.7e-09 37.6 0.0 2.9 4 0 0 4 4 4 1 Tyrosine phosphatase family C-terminal region PTPlike_phytase PF14566.1 AEO56003.1 - 0.046 13.7 0.0 0.077 13.0 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase PF00102.22 AEO56003.1 - 0.049 12.9 0.0 0.068 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 AEO56003.1 - 0.05 12.9 0.0 0.072 12.4 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.15 AEO56003.1 - 0.12 11.9 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain B12-binding_2 PF02607.12 AEO56003.1 - 0.28 11.2 1.1 3.2 7.8 0.1 2.7 2 1 1 3 3 3 0 B12 binding domain Ribosomal_S4 PF00163.14 AEO56004.1 - 5.1e-12 46.0 3.9 7.3e-12 45.5 2.2 1.6 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 AEO56004.1 - 1.7e-11 43.3 0.0 6e-11 41.5 0.0 1.9 2 0 0 2 2 2 1 S4 domain Herpes_LAMP2 PF06126.6 AEO56004.1 - 0.045 12.1 0.3 0.051 11.9 0.2 1.1 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 THDPS_N_2 PF14805.1 AEO56004.1 - 0.11 12.3 0.1 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal Ribosomal_S18 PF01084.15 AEO56005.1 - 1e-13 50.9 0.0 4.3e-13 48.8 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein S18 PPR_3 PF13812.1 AEO56006.1 - 4.7e-09 35.8 0.6 0.0082 16.3 0.0 5.9 6 0 0 6 6 6 2 Pentatricopeptide repeat domain PPR PF01535.15 AEO56006.1 - 8e-08 31.7 0.0 0.08 12.9 0.0 4.9 4 0 0 4 4 4 3 PPR repeat PPR_2 PF13041.1 AEO56006.1 - 0.0002 21.2 0.0 1.3 9.0 0.0 4.4 5 0 0 5 5 5 2 PPR repeat family TPR_14 PF13428.1 AEO56006.1 - 0.0017 18.8 0.5 1.1 10.0 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat FTA4 PF13093.1 AEO56007.1 - 4.3e-64 215.8 0.0 5e-64 215.6 0.0 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 ArfGap PF01412.13 AEO56008.1 - 4e-39 133.0 0.1 8.3e-39 131.9 0.1 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf UBA PF00627.26 AEO56008.1 - 3.6e-05 23.4 0.1 7.3e-05 22.4 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Methyltransf_23 PF13489.1 AEO56009.1 - 5e-16 58.8 0.0 8.8e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO56009.1 - 2.8e-07 31.1 0.0 5.3e-06 26.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO56009.1 - 1.1e-06 28.3 0.0 1.1e-05 25.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO56009.1 - 3e-05 24.4 0.0 0.00027 21.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO56009.1 - 0.00027 21.3 0.0 0.00044 20.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO56009.1 - 0.004 17.1 0.0 0.057 13.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO56009.1 - 0.0085 16.4 0.0 0.029 14.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 AEO56009.1 - 0.0096 15.9 0.0 0.018 15.0 0.0 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 AEO56009.1 - 0.014 14.4 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.9 AEO56009.1 - 0.017 14.5 0.0 0.9 8.8 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain Ubie_methyltran PF01209.13 AEO56009.1 - 0.053 12.6 0.0 0.42 9.6 0.0 2.0 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Pyridoxal_deC PF00282.14 AEO56011.1 - 5.5e-22 77.7 0.0 7.5e-22 77.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 AEO56011.1 - 0.015 14.0 0.0 0.14 10.8 0.0 2.0 2 0 0 2 2 2 0 Aminotransferase class-V Aminotran_1_2 PF00155.16 AEO56011.1 - 0.046 12.6 0.0 0.087 11.7 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II Beta_elim_lyase PF01212.16 AEO56011.1 - 0.069 12.2 0.0 0.096 11.8 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Ribosomal_60s PF00428.14 AEO56011.1 - 0.21 11.9 3.6 1 9.8 2.5 2.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF2462 PF09495.5 AEO56012.1 - 1.4e-11 44.9 15.4 1.9e-11 44.5 10.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) ThiF PF00899.16 AEO56013.1 - 1.1e-28 99.7 0.0 2.2e-28 98.8 0.0 1.5 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 AEO56013.1 - 0.013 15.6 0.0 0.05 13.7 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase dCMP_cyt_deam_1 PF00383.17 AEO56014.1 - 4.8e-27 93.5 1.0 6.9e-27 93.0 0.7 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region AAA_17 PF13207.1 AEO56014.1 - 9.2e-05 23.2 0.1 0.00026 21.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AEO56014.1 - 0.0023 18.2 0.1 0.025 14.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain CoaE PF01121.15 AEO56014.1 - 0.094 12.1 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Dephospho-CoA kinase TMEMspv1-c74-12 PF11044.3 AEO56015.1 - 0.015 14.8 0.6 0.02 14.4 0.4 1.2 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein PMP1_2 PF08114.6 AEO56015.1 - 0.065 12.7 1.3 0.093 12.2 0.9 1.3 1 0 0 1 1 1 0 ATPase proteolipid family Glyco_hydro_61 PF03443.9 AEO56016.1 - 2e-66 223.9 0.6 2.4e-66 223.6 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 2Fe-2S_thioredx PF01257.14 AEO56017.1 - 1e-60 203.5 0.1 1.3e-60 203.2 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin HSP9_HSP12 PF04119.7 AEO56017.1 - 0.021 14.9 0.1 0.045 13.8 0.1 1.5 1 0 0 1 1 1 0 Heat shock protein 9/12 Kelch_3 PF13415.1 AEO56018.1 - 1.2e-26 92.1 26.0 4.4e-07 29.8 0.1 8.8 8 1 0 8 8 8 6 Galactose oxidase, central domain Kelch_5 PF13854.1 AEO56018.1 - 1.8e-17 62.8 10.1 1.3e-06 28.1 0.0 6.7 7 1 0 7 7 7 4 Kelch motif Kelch_6 PF13964.1 AEO56018.1 - 2.4e-17 62.2 5.7 1.8e-05 24.7 0.0 6.1 4 2 2 6 6 6 3 Kelch motif Kelch_2 PF07646.10 AEO56018.1 - 2.8e-16 58.5 1.7 2e-06 27.3 0.1 6.1 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.20 AEO56018.1 - 6.5e-16 57.6 5.1 5.8e-06 25.7 0.0 6.0 6 1 0 6 6 6 3 Kelch motif Kelch_4 PF13418.1 AEO56018.1 - 3.1e-15 55.6 21.4 0.00017 21.3 0.2 7.5 7 1 1 8 8 8 4 Galactose oxidase, central domain SPOR PF05036.8 AEO56018.1 - 0.012 15.7 0.1 0.045 13.9 0.0 1.9 2 0 0 2 2 2 0 Sporulation related domain Ceramidase_alk PF04734.8 AEO56019.1 - 1.2e-279 928.9 0.0 1.4e-279 928.7 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase cNMP_binding PF00027.24 AEO56020.1 - 1.4e-43 146.5 0.0 1.7e-22 79.0 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain CDC50 PF03381.10 AEO56021.1 - 1.7e-92 309.5 0.7 2e-92 309.3 0.5 1.0 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family ATG27 PF09451.5 AEO56021.1 - 0.096 11.9 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Autophagy-related protein 27 SPT16 PF08644.6 AEO56023.1 - 4.1e-58 195.5 0.2 4.1e-58 195.5 0.1 2.5 3 0 0 3 3 3 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 AEO56023.1 - 6.7e-57 191.5 0.7 1.9e-56 190.0 0.5 1.8 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 AEO56023.1 - 9.6e-25 87.3 0.0 1.7e-24 86.5 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 AEO56023.1 - 1.8e-22 79.1 0.0 5.3e-22 77.6 0.0 1.9 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Band_3_cyto PF07565.8 AEO56025.1 - 0.021 14.3 0.5 0.036 13.5 0.3 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Spt20 PF12090.3 AEO56025.1 - 0.036 13.4 4.2 0.065 12.5 2.9 1.4 1 0 0 1 1 1 0 Spt20 family FimP PF09766.4 AEO56025.1 - 0.15 11.0 12.5 0.29 10.1 8.7 1.4 1 0 0 1 1 1 0 Fms-interacting protein RR_TM4-6 PF06459.7 AEO56025.1 - 0.38 10.6 5.0 0.78 9.5 3.5 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Suf PF05843.9 AEO56025.1 - 0.71 9.5 16.2 0.13 11.9 8.5 1.7 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Ndc1_Nup PF09531.5 AEO56025.1 - 1.2 7.4 5.5 1.4 7.2 3.8 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF1183 PF06682.7 AEO56025.1 - 1.3 8.6 10.1 0.79 9.2 4.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) PEX11 PF05648.9 AEO56025.1 - 5 6.3 0.0 5 6.3 0.0 2.1 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) Pex16 PF08610.5 AEO56025.1 - 5.6 5.8 6.8 4.5 6.1 3.8 1.6 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) GCS PF03074.11 AEO56026.1 - 8.8e-155 515.3 0.0 7.3e-124 413.5 0.0 2.1 1 1 1 2 2 2 2 Glutamate-cysteine ligase CFEM PF05730.6 AEO56027.1 - 0.025 14.3 3.8 0.05 13.4 2.6 1.5 1 0 0 1 1 1 0 CFEM domain Mid2 PF04478.7 AEO56027.1 - 0.05 13.0 0.1 0.13 11.6 0.0 1.7 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DEAD PF00270.24 AEO56028.1 - 2.9e-33 114.7 0.1 1.1e-32 112.8 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO56028.1 - 2.8e-22 78.3 0.1 5.1e-22 77.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 AEO56028.1 - 0.0015 18.1 0.8 0.056 13.1 0.1 2.7 2 1 1 3 3 3 1 Part of AAA domain CMS1 PF14617.1 AEO56028.1 - 0.011 14.8 0.1 0.021 13.9 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Helicase_C_2 PF13307.1 AEO56028.1 - 0.021 14.7 0.0 0.057 13.3 0.0 1.7 2 0 0 2 2 2 0 Helicase C-terminal domain AAA_30 PF13604.1 AEO56028.1 - 0.033 13.7 0.0 0.1 12.1 0.0 1.8 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.1 AEO56028.1 - 0.24 11.5 2.1 8.6 6.5 1.0 2.9 2 1 0 2 2 2 0 AAA domain FCH PF00611.18 AEO56029.1 - 1.8e-22 79.3 0.0 1.8e-22 79.3 0.0 3.6 3 2 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 AEO56029.1 - 5.7e-21 73.8 0.5 4.2e-13 48.6 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain C1_1 PF00130.17 AEO56029.1 - 1.4e-14 53.5 5.6 2.1e-14 52.9 3.9 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_1 PF00018.23 AEO56029.1 - 1.5e-13 49.9 0.0 2e-05 23.8 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_3 PF08239.6 AEO56029.1 - 0.00058 19.9 0.2 0.024 14.8 0.0 2.5 2 0 0 2 2 2 1 Bacterial SH3 domain SH3_2 PF07653.12 AEO56029.1 - 0.0028 17.0 0.0 0.61 9.6 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain 7TM_GPCR_Sri PF10327.4 AEO56029.1 - 0.086 11.7 0.1 0.13 11.1 0.1 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sri Spc7 PF08317.6 AEO56029.1 - 0.22 10.1 14.6 0.57 8.7 4.4 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein C1_2 PF03107.11 AEO56029.1 - 0.57 10.3 7.8 0.97 9.6 5.4 1.3 1 0 0 1 1 1 0 C1 domain Glyco_hydro_72 PF03198.9 AEO56030.1 - 2.9e-119 397.7 3.1 3.9e-119 397.2 2.2 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 AEO56030.1 - 8.5e-06 25.1 1.3 0.00029 20.1 0.9 2.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) GAF PF01590.21 AEO56031.1 - 7.3e-05 22.9 0.1 0.0001 22.4 0.1 1.3 1 1 0 1 1 1 1 GAF domain GAF_2 PF13185.1 AEO56031.1 - 0.00015 22.2 0.0 0.00019 21.9 0.0 1.1 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.1 AEO56031.1 - 0.034 14.2 0.0 0.048 13.7 0.0 1.4 1 1 0 1 1 1 0 GAF domain Coatomer_E PF04733.9 AEO56035.1 - 2.1e-62 210.9 1.7 2.5e-62 210.7 1.1 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_15 PF13429.1 AEO56035.1 - 8.8e-08 31.5 4.0 0.003 16.6 0.0 2.3 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 AEO56035.1 - 2.1e-06 27.9 23.2 0.0042 17.3 1.8 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 AEO56035.1 - 7.3e-05 23.3 2.8 7.3e-05 23.3 1.9 5.0 2 2 4 6 6 6 1 Tetratricopeptide repeat Apc3 PF12895.2 AEO56035.1 - 0.00011 22.2 0.2 0.62 10.2 0.1 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 AEO56035.1 - 0.0006 19.3 0.5 0.083 12.5 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 AEO56035.1 - 0.0008 19.8 1.4 0.0008 19.8 1.0 6.1 4 3 4 8 8 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 AEO56035.1 - 0.0009 18.8 6.9 0.01 15.4 0.3 3.9 5 1 1 6 6 5 1 TPR repeat TPR_2 PF07719.12 AEO56035.1 - 0.0015 18.3 0.1 0.0015 18.3 0.0 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 AEO56035.1 - 0.0044 17.1 0.1 16 6.0 0.0 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Type_III_YscG PF09477.5 AEO56035.1 - 0.0044 17.0 4.8 0.18 11.9 0.1 3.6 1 1 0 2 2 2 1 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_8 PF13181.1 AEO56035.1 - 0.0055 16.3 0.1 0.098 12.4 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 AEO56035.1 - 0.0072 16.1 8.0 0.47 10.3 0.1 3.9 3 1 0 3 3 3 1 Tetratricopeptide repeat Clathrin PF00637.15 AEO56035.1 - 0.029 13.9 0.0 0.57 9.7 0.0 2.2 2 0 0 2 2 2 0 Region in Clathrin and VPS TPR_6 PF13174.1 AEO56035.1 - 0.032 14.6 4.3 1.6 9.3 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Sigma70_r3 PF04539.11 AEO56035.1 - 0.057 13.3 0.7 0.94 9.4 0.1 2.9 3 0 0 3 3 3 0 Sigma-70 region 3 TPR_4 PF07721.9 AEO56035.1 - 0.063 13.7 1.1 0.063 13.7 0.7 6.3 8 0 0 8 8 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 AEO56035.1 - 0.11 12.4 12.9 0.32 10.9 0.4 4.4 3 2 3 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.1 AEO56035.1 - 0.11 12.4 8.9 7.6 6.6 0.3 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.1 AEO56035.1 - 0.2 11.7 7.1 5.2 7.2 0.1 3.6 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 AEO56035.1 - 0.25 11.2 9.1 4 7.4 0.1 5.6 6 1 1 7 7 6 0 Tetratricopeptide repeat PS_Dcarbxylase PF02666.10 AEO56036.1 - 5.8e-52 175.9 0.0 8.5e-52 175.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 AEO56036.1 - 6e-36 122.1 0.0 1.2e-17 63.4 0.0 2.5 2 0 0 2 2 2 2 C2 domain EF-hand_7 PF13499.1 AEO56036.1 - 4.7e-05 23.4 0.2 0.00013 22.0 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 AEO56036.1 - 0.00061 18.9 0.0 0.0017 17.5 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 AEO56036.1 - 0.0029 17.3 0.0 0.012 15.3 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.1 AEO56036.1 - 0.06 12.9 0.2 0.21 11.2 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain pair CDC45 PF02724.9 AEO56036.1 - 0.11 10.4 0.3 0.19 9.7 0.2 1.2 1 0 0 1 1 1 0 CDC45-like protein MSA-2c PF12238.3 AEO56036.1 - 9.2 5.8 13.1 0.27 10.8 1.2 2.6 2 0 0 2 2 2 0 Merozoite surface antigen 2c DUF605 PF04652.11 AEO56037.1 - 5.8 6.2 10.2 6.4 6.0 7.1 1.0 1 0 0 1 1 1 0 Vta1 like DUF3405 PF11885.3 AEO56038.1 - 1.8e-181 603.7 4.9 5.1e-181 602.2 3.4 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3405) LIM PF00412.17 AEO56039.1 - 3.8e-21 74.9 13.5 4.9e-12 45.7 3.0 2.2 2 0 0 2 2 2 2 LIM domain NAD_binding_5 PF07994.7 AEO56041.1 - 1.4e-113 379.2 0.1 1.7e-113 378.9 0.1 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 AEO56041.1 - 2.9e-46 155.8 0.7 4.7e-46 155.2 0.5 1.3 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase AMP-binding PF00501.23 AEO56042.1 - 4e-78 262.6 0.0 5.1e-78 262.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 AEO56042.1 - 1.4e-11 45.1 0.1 5.5e-11 43.2 0.1 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.11 AEO56043.1 - 1.2e-16 60.3 35.6 1.3e-10 40.5 12.0 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO56043.1 - 8.7e-13 47.6 25.1 4.1e-06 25.6 1.1 3.1 2 1 1 3 3 3 3 Sugar (and other) transporter DnaJ PF00226.26 AEO56044.1 - 2.9e-14 52.5 0.0 4.8e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain SCP2 PF02036.12 AEO56045.1 - 2.7e-25 88.6 0.3 3.3e-25 88.3 0.2 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 AEO56045.1 - 3.3e-08 33.5 0.1 4.1e-08 33.2 0.1 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.1 AEO56045.1 - 0.024 14.0 0.0 0.028 13.7 0.0 1.1 1 0 0 1 1 1 0 Sterol carrier protein domain DUF3319 PF11782.3 AEO56045.1 - 0.045 13.5 0.0 0.098 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3319) Ran_BP1 PF00638.13 AEO56046.1 - 9.8e-13 48.2 0.1 2.9e-11 43.4 0.0 2.3 1 1 0 1 1 1 1 RanBP1 domain PilJ PF13675.1 AEO56048.1 - 0.015 15.6 0.0 7.5 6.9 0.0 2.4 2 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term IncA PF04156.9 AEO56048.1 - 0.015 14.9 0.8 0.019 14.5 0.6 1.1 1 0 0 1 1 1 0 IncA protein Snapin_Pallidin PF14712.1 AEO56048.1 - 0.033 14.4 0.1 0.071 13.4 0.1 1.5 1 1 0 1 1 1 0 Snapin/Pallidin FlaC_arch PF05377.6 AEO56048.1 - 0.094 12.6 0.2 1.3 9.0 0.0 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Tropomyosin_1 PF12718.2 AEO56048.1 - 0.12 12.2 0.5 0.17 11.7 0.3 1.2 1 0 0 1 1 1 0 Tropomyosin like Tbf5 PF06331.7 AEO56049.1 - 1.1e-30 105.1 0.6 1.2e-30 105.0 0.4 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 CmcI PF04989.7 AEO56049.1 - 0.015 14.6 0.1 0.015 14.5 0.1 1.0 1 0 0 1 1 1 0 Cephalosporin hydroxylase TYW3 PF02676.9 AEO56049.1 - 0.018 14.1 0.1 0.018 14.1 0.0 1.0 1 0 0 1 1 1 0 Methyltransferase TYW3 ECH PF00378.15 AEO56050.1 - 1.5e-37 129.0 0.9 5.6e-37 127.1 0.6 1.7 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 AEO56050.1 - 0.02 15.0 0.0 0.055 13.6 0.0 1.7 2 0 0 2 2 2 0 2-enoyl-CoA Hydratase C-terminal region SAM_2 PF07647.12 AEO56051.1 - 4.7e-15 55.1 0.1 1e-14 54.0 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.24 AEO56051.1 - 3e-08 33.8 0.0 9.5e-08 32.1 0.0 2.0 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 AEO56051.1 - 5.8e-05 23.3 0.0 0.00017 21.7 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain SAM_1 PF00536.25 AEO56051.1 - 0.027 14.6 0.1 0.056 13.6 0.1 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Gastrin PF00918.12 AEO56051.1 - 0.027 15.2 0.6 0.46 11.3 0.0 3.4 2 1 1 3 3 3 0 Gastrin/cholecystokinin family PH_8 PF15409.1 AEO56051.1 - 0.045 13.8 0.0 0.31 11.1 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain Nucleopor_Nup85 PF07575.8 AEO56052.1 - 1.7e-11 43.0 0.0 3.1e-10 38.8 0.0 2.5 1 1 0 1 1 1 1 Nup85 Nucleoporin T2SI PF02501.12 AEO56052.1 - 0.041 13.8 0.0 0.094 12.6 0.0 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein I DUF952 PF06108.7 AEO56053.1 - 6.5e-13 48.3 0.0 3.2e-12 46.1 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF952) ADH_N PF08240.7 AEO56054.1 - 7e-29 99.7 1.0 1.8e-28 98.4 0.7 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AEO56054.1 - 5.8e-21 74.3 0.2 1.1e-20 73.5 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ThiF PF00899.16 AEO56054.1 - 0.027 14.2 3.7 0.55 10.0 1.9 2.3 1 1 1 2 2 2 0 ThiF family UDPG_MGDP_dh_N PF03721.9 AEO56054.1 - 0.062 12.6 0.1 0.1 11.9 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain zf-AN1 PF01428.11 AEO56055.1 - 8.2e-11 41.6 11.3 1.1e-10 41.1 7.8 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger Transp_Tc5_C PF04236.10 AEO56055.1 - 3.8 7.7 7.1 3 8.1 3.8 1.7 2 1 0 2 2 2 0 Tc5 transposase C-terminal domain HhH-GPD PF00730.20 AEO56056.1 - 2.3e-17 63.2 0.0 4.7e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 AEO56056.1 - 1.2e-07 30.9 0.0 3.4e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif DUF3439 PF11921.3 AEO56056.1 - 0.03 14.0 1.1 0.03 14.0 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DUF676 PF05057.9 AEO56057.1 - 3e-51 173.7 0.0 4.5e-51 173.2 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 AEO56057.1 - 2.4e-06 27.6 0.1 2.4e-06 27.6 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO56057.1 - 2.6e-06 27.2 0.0 7.3e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Tim54 PF11711.3 AEO56057.1 - 0.005 15.4 0.3 0.005 15.4 0.2 2.0 2 0 0 2 2 2 1 Inner membrane protein import complex subunit Tim54 Endostatin PF06482.6 AEO56057.1 - 0.017 14.5 6.6 0.032 13.6 4.6 1.4 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Claudin_2 PF13903.1 AEO56057.1 - 0.046 13.4 2.9 0.082 12.5 2.0 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Pex16 PF08610.5 AEO56057.1 - 0.051 12.5 1.0 0.1 11.5 0.7 1.4 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Dicty_REP PF05086.7 AEO56057.1 - 0.1 10.3 9.9 0.19 9.4 6.9 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.3 AEO56057.1 - 0.32 10.7 7.2 0.17 11.6 2.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) ABC2_membrane_3 PF12698.2 AEO56057.1 - 2.2 7.2 6.9 3.1 6.7 4.8 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein CENP-T PF15511.1 AEO56057.1 - 3.3 6.8 14.2 0.79 8.8 3.7 2.1 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T DUF2201_N PF13203.1 AEO56057.1 - 8.5 5.4 10.5 1.3 8.1 0.1 2.3 2 0 0 2 2 2 0 Putative metallopeptidase domain GDPD PF03009.12 AEO56058.1 - 1.7e-30 106.3 0.0 2e-29 102.8 0.0 2.0 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 AEO56058.1 - 0.0004 20.4 1.0 0.001 19.1 0.7 1.7 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family SR-25 PF10500.4 AEO56058.1 - 0.33 10.3 9.9 0.49 9.8 6.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Fungal_trans PF04082.13 AEO56059.1 - 1.3e-31 109.4 0.3 2.2e-31 108.6 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO56059.1 - 2e-10 40.4 11.1 4.2e-10 39.3 7.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF641 PF04859.7 AEO56059.1 - 0.063 13.0 0.5 0.16 11.7 0.3 1.7 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Cep57_MT_bd PF06657.8 AEO56059.1 - 0.3 11.0 3.8 0.64 10.0 0.2 2.8 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 SET PF00856.23 AEO56060.1 - 5.6e-05 23.4 0.0 0.00013 22.2 0.0 1.6 1 0 0 1 1 1 1 SET domain Translin PF01997.11 AEO56061.1 - 2.5e-49 167.5 0.0 3e-49 167.3 0.0 1.0 1 0 0 1 1 1 1 Translin family GMP_synt_C PF00958.17 AEO56061.1 - 0.05 13.3 0.1 0.25 11.0 0.0 2.1 2 1 0 2 2 2 0 GMP synthase C terminal domain PIG-F PF06699.6 AEO56062.1 - 3.6e-53 180.3 5.6 3.2e-52 177.2 3.9 2.0 1 1 0 1 1 1 1 GPI biosynthesis protein family Pig-F ABC2_membrane_5 PF13346.1 AEO56062.1 - 0.098 11.9 2.2 0.15 11.3 1.5 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Mito_carr PF00153.22 AEO56063.1 - 1e-54 182.2 0.0 2e-19 69.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CYSTM PF12734.2 AEO56063.1 - 9.2 6.4 6.9 14 5.8 0.2 2.4 2 0 0 2 2 2 0 Cysteine-rich TM module stress tolerance Ribosomal_L22e PF01776.12 AEO56064.1 - 9.4e-47 157.6 0.4 1.1e-46 157.3 0.3 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family MMR_HSR1_C PF08438.5 AEO56065.1 - 1.2e-32 112.3 0.0 2.6e-32 111.3 0.0 1.6 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 AEO56065.1 - 1.3e-14 54.1 0.0 2.8e-14 53.0 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AEO56065.1 - 1.3e-05 24.4 0.0 0.00051 19.3 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 AEO56065.1 - 0.0056 16.5 2.1 0.18 11.6 0.4 2.9 3 0 0 3 3 3 1 Dynamin family GTP_EFTU PF00009.22 AEO56065.1 - 0.012 15.0 0.3 0.58 9.5 0.0 2.5 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 AEO56065.1 - 0.035 14.3 0.0 0.36 11.1 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Zeta_toxin PF06414.7 AEO56065.1 - 0.052 12.6 0.1 0.14 11.1 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin Pmp3 PF01679.12 AEO56066.1 - 1.8e-26 91.5 5.2 2e-26 91.4 3.6 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator TM_helix PF05552.7 AEO56066.1 - 0.022 14.4 0.5 0.022 14.4 0.3 1.8 2 0 0 2 2 2 0 Conserved TM helix RP1-2 PF12042.3 AEO56067.1 - 0.012 15.2 0.6 0.012 15.2 0.4 1.6 2 0 0 2 2 2 0 Tubuliform egg casing silk strands structural domain CP_ATPgrasp_2 PF14403.1 AEO56068.1 - 0.0012 17.5 0.0 0.002 16.8 0.0 1.3 1 0 0 1 1 1 1 Circularly permuted ATP-grasp type 2 Host_attach PF10116.4 AEO56068.1 - 0.0015 18.7 0.2 0.0027 17.9 0.1 1.3 1 0 0 1 1 1 1 Protein required for attachment to host cells ATPgrasp_ST PF14397.1 AEO56068.1 - 0.19 10.7 0.0 0.3 10.1 0.0 1.2 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp TauD PF02668.11 AEO56069.1 - 6.1e-18 65.4 0.5 1.2e-17 64.4 0.3 1.5 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 AEO56069.1 - 0.0067 15.3 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 CsiD DUF3439 PF11921.3 AEO56069.1 - 0.57 9.9 4.3 0.79 9.4 1.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Orn_Arg_deC_N PF02784.11 AEO56070.1 - 1.2e-68 231.0 0.0 1.7e-68 230.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 AEO56070.1 - 7.2e-22 77.2 0.0 1.3e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.19 AEO56070.1 - 0.0023 17.2 0.0 0.0039 16.5 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Snf7 PF03357.16 AEO56073.1 - 5.7e-33 113.6 21.2 5.7e-33 113.6 14.7 2.0 1 1 1 2 2 2 1 Snf7 MutS_III PF05192.13 AEO56073.1 - 0.025 14.3 4.2 0.033 13.9 2.9 1.3 1 0 0 1 1 1 0 MutS domain III Misat_Tub_SegII PF10644.4 AEO56073.1 - 0.25 11.4 4.7 0.18 11.8 1.3 2.2 1 1 1 2 2 2 0 Misato Segment II tubulin-like domain XkdN PF08890.6 AEO56073.1 - 0.35 10.5 6.7 0.14 11.9 2.1 2.0 1 1 1 2 2 2 0 Phage XkdN-like protein GTPase_Cys_C PF12631.2 AEO56073.1 - 0.39 11.1 3.8 0.25 11.7 0.4 2.3 1 1 1 2 2 2 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE DUF3138 PF11336.3 AEO56073.1 - 1.1 7.2 7.3 0.19 9.8 1.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) IL3 PF02059.10 AEO56073.1 - 1.3 9.0 6.4 2.7 7.9 0.9 2.3 1 1 1 2 2 2 0 Interleukin-3 Fmp27_WPPW PF10359.4 AEO56073.1 - 1.3 7.3 12.9 1.2 7.5 8.3 1.3 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain CK2S PF15011.1 AEO56073.1 - 1.4 8.6 9.3 4.4 7.0 1.1 2.6 1 1 2 3 3 3 0 Casein Kinase 2 substrate Allexi_40kDa PF05549.6 AEO56073.1 - 1.7 7.8 8.7 4.2 6.5 6.0 1.6 1 1 0 1 1 1 0 Allexivirus 40kDa protein Occludin_ELL PF07303.8 AEO56073.1 - 5.2 7.8 12.1 2.9 8.6 1.9 2.8 3 1 0 3 3 2 0 Occludin homology domain Ten1 PF12658.2 AEO56074.1 - 7.2e-30 103.2 0.0 8.7e-30 103.0 0.0 1.1 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Ten1_2 PF15490.1 AEO56074.1 - 0.0075 15.8 0.0 0.0094 15.5 0.0 1.3 1 1 0 1 1 1 1 Telomere-capping, CST complex subunit RAM PF15320.1 AEO56075.1 - 0.019 15.1 1.2 0.03 14.5 0.8 1.3 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein ICE2 PF08426.5 AEO56076.1 - 3.7e-147 490.2 15.3 4.3e-147 490.0 10.6 1.0 1 0 0 1 1 1 1 ICE2 AT_hook PF02178.14 AEO56077.1 - 0.0028 17.1 46.7 0.15 11.8 1.9 4.9 4 0 0 4 4 4 4 AT hook motif Cwf_Cwc_15 PF04889.7 AEO56077.1 - 0.56 9.8 11.7 0.75 9.4 8.1 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.7 AEO56077.1 - 4 5.2 15.6 5.8 4.6 10.8 1.4 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 AEO56077.1 - 4.1 6.5 12.8 5.6 6.1 8.8 1.2 1 0 0 1 1 1 0 NOA36 protein HA2 PF04408.18 AEO56078.1 - 4.2e-21 74.8 2.1 6.8e-21 74.2 0.1 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 AEO56078.1 - 1.2e-13 50.6 0.1 3.9e-13 49.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 AEO56078.1 - 5.1e-13 48.8 0.0 1.5e-12 47.3 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 AEO56078.1 - 3.9e-09 36.2 0.0 8.7e-09 35.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase RWD PF05773.17 AEO56078.1 - 2.2e-08 33.9 0.1 5.9e-08 32.6 0.1 1.8 1 0 0 1 1 1 1 RWD domain UBA PF00627.26 AEO56078.1 - 6.1e-07 29.0 1.1 0.0012 18.6 0.0 3.7 3 0 0 3 3 3 2 UBA/TS-N domain AAA_22 PF13401.1 AEO56078.1 - 0.00028 21.0 0.1 0.00067 19.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AEO56078.1 - 0.00029 20.5 0.0 0.0011 18.7 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_29 PF13555.1 AEO56078.1 - 0.01 15.3 0.0 0.025 14.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DND1_DSRM PF14709.1 AEO56078.1 - 0.016 15.5 0.1 0.016 15.5 0.0 2.6 3 0 0 3 3 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 KaiC PF06745.8 AEO56078.1 - 0.016 14.2 0.0 0.032 13.3 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.1 AEO56078.1 - 0.021 15.1 0.1 0.054 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Aldo_ket_red PF00248.16 AEO56078.1 - 0.042 12.6 0.0 0.077 11.8 0.0 1.4 1 0 0 1 1 1 0 Aldo/keto reductase family T2SE PF00437.15 AEO56078.1 - 0.055 12.3 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.1 AEO56078.1 - 0.066 12.5 0.0 0.17 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 AEO56078.1 - 0.09 11.9 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Zot PF05707.7 AEO56078.1 - 0.14 11.6 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) DLIC PF05783.6 AEO56078.1 - 8.1 4.9 7.3 15 4.1 5.1 1.4 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Arm PF00514.18 AEO56079.1 - 1.1e-96 313.7 15.1 2.9e-14 52.2 0.1 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 AEO56079.1 - 3.8e-27 94.3 0.2 2.2e-11 43.9 0.0 5.7 1 1 5 6 6 6 5 HEAT repeats HEAT_EZ PF13513.1 AEO56079.1 - 7.9e-24 83.4 8.8 6.5e-10 39.2 0.0 6.4 5 1 2 7 7 7 4 HEAT-like repeat IBB PF01749.15 AEO56079.1 - 7.2e-23 80.5 1.1 1.2e-22 79.8 0.8 1.4 1 0 0 1 1 1 1 Importin beta binding domain HEAT PF02985.17 AEO56079.1 - 1.8e-22 77.3 1.2 6.9e-07 28.8 0.0 7.3 8 0 0 8 8 8 4 HEAT repeat Arm_2 PF04826.8 AEO56079.1 - 1.3e-10 40.8 0.0 0.0046 16.1 0.0 4.0 2 1 2 4 4 4 3 Armadillo-like Adaptin_N PF01602.15 AEO56079.1 - 1.5e-07 30.1 0.0 1.1e-05 24.0 0.0 2.8 1 1 2 3 3 3 1 Adaptin N terminal region V-ATPase_H_C PF11698.3 AEO56079.1 - 5.7e-05 23.0 0.0 0.96 9.3 0.0 4.6 2 1 0 4 4 4 1 V-ATPase subunit H HEAT_PBS PF03130.11 AEO56079.1 - 0.00024 21.2 0.5 0.45 11.1 0.0 4.5 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat Proteasom_PSMB PF10508.4 AEO56079.1 - 0.0011 17.3 0.1 0.4 8.8 0.0 3.0 2 1 1 3 3 3 1 Proteasome non-ATPase 26S subunit Glycos_trans_3N PF02885.12 AEO56079.1 - 0.038 13.5 0.0 14 5.3 0.0 3.5 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain Mo25 PF08569.6 AEO56079.1 - 0.13 11.2 0.0 0.32 9.9 0.0 1.6 1 0 0 1 1 1 0 Mo25-like SURF6 PF04935.7 AEO56079.1 - 3 7.0 8.3 4.5 6.4 5.8 1.2 1 0 0 1 1 1 0 Surfeit locus protein 6 POT1 PF02765.12 AEO56080.1 - 2.1e-15 56.9 0.0 4.5e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 tRNA_anti-codon PF01336.20 AEO56080.1 - 0.0024 17.7 0.3 0.33 10.8 0.0 2.9 3 0 0 3 3 3 2 OB-fold nucleic acid binding domain STAG PF08514.6 AEO56081.1 - 1.7e-29 101.8 0.6 5.2e-29 100.3 0.4 1.8 1 0 0 1 1 1 1 STAG domain DUF1664 PF07889.7 AEO56081.1 - 0.021 14.6 0.7 0.86 9.4 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) RXT2_N PF08595.6 AEO56081.1 - 0.29 10.9 12.7 1.5 8.6 1.7 3.8 3 0 0 3 3 3 0 RXT2-like, N-terminal UreD PF01774.12 AEO56082.1 - 4e-57 193.0 0.0 5e-57 192.7 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein RNA_pol_Rpc4 PF05132.9 AEO56083.1 - 1.7e-23 83.0 0.0 1.7e-23 83.0 0.0 3.7 4 1 0 4 4 4 1 RNA polymerase III RPC4 Imm6 PF14434.1 AEO56083.1 - 0.084 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Immunity protein Imm6 DAO PF01266.19 AEO56084.1 - 1.6e-12 47.0 5.8 9.2e-08 31.3 0.9 2.6 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 AEO56084.1 - 1.7e-10 40.5 0.0 2.6e-05 23.4 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 AEO56084.1 - 2.1e-07 31.0 0.0 1e-06 28.7 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 AEO56084.1 - 0.0001 21.3 0.1 0.0026 16.7 0.2 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 AEO56084.1 - 0.00011 21.1 1.1 0.00031 19.7 0.2 1.8 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 AEO56084.1 - 0.00065 18.2 0.1 0.0012 17.3 0.1 1.5 1 1 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.1 AEO56084.1 - 0.00071 19.5 0.1 0.0018 18.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 AEO56084.1 - 0.0021 18.4 0.2 0.084 13.2 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AEO56084.1 - 0.017 15.2 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 AEO56084.1 - 0.092 11.5 0.7 0.13 11.1 0.5 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A MFS_1 PF07690.11 AEO56085.1 - 1.5e-31 109.4 42.0 1.5e-31 109.4 29.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.13 AEO56086.1 - 0.0018 18.1 12.3 0.0033 17.2 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.5 AEO56086.1 - 0.013 14.7 0.1 0.035 13.3 0.1 1.8 1 0 0 1 1 1 0 Histone chaperone domain CHZ Cyclin_N PF00134.18 AEO56087.1 - 3.5e-43 146.2 0.3 7.7e-43 145.0 0.2 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 AEO56087.1 - 1.2e-32 112.3 0.2 2.9e-32 111.0 0.1 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain Mito_carr PF00153.22 AEO56088.1 - 3.4e-74 244.6 0.8 5.3e-26 90.1 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.27 AEO56088.1 - 8.6e-15 52.8 0.2 1.8e-07 29.9 0.0 5.3 5 0 0 5 5 5 2 EF hand EF-hand_7 PF13499.1 AEO56088.1 - 5.9e-14 51.9 5.5 1.4e-07 31.5 0.1 4.4 2 2 3 5 5 5 3 EF-hand domain pair EF-hand_8 PF13833.1 AEO56088.1 - 5.8e-12 45.0 0.3 0.082 12.5 0.0 4.9 4 0 0 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 AEO56088.1 - 8.1e-12 43.9 6.7 1.5e-05 24.4 0.0 6.2 6 0 0 6 6 6 2 EF-hand domain EF-hand_5 PF13202.1 AEO56088.1 - 1.2e-09 37.0 1.0 5.5e-07 28.6 0.1 3.5 4 0 0 4 4 4 2 EF hand EF-hand_10 PF14788.1 AEO56088.1 - 0.043 13.4 1.0 16 5.2 0.0 3.6 3 1 0 3 3 3 0 EF hand EF-hand_9 PF14658.1 AEO56088.1 - 0.067 13.1 0.0 36 4.3 0.0 3.6 4 0 0 4 4 4 0 EF-hand domain PQ-loop PF04193.9 AEO56090.1 - 1.4e-31 107.8 10.7 3.8e-16 58.3 0.9 2.6 2 0 0 2 2 2 2 PQ loop repeat Vma12 PF11712.3 AEO56090.1 - 5.6 6.6 5.5 1.4 8.6 1.1 2.1 2 1 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase PBP_sp32 PF07222.7 AEO56091.1 - 0.052 12.7 0.2 0.066 12.3 0.1 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Mucin PF01456.12 AEO56091.1 - 0.68 9.6 17.1 1.2 8.8 11.9 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.7 AEO56091.1 - 1.3 6.6 3.8 1.4 6.5 2.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Zn_clus PF00172.13 AEO56092.1 - 1.7e-08 34.2 11.6 2.9e-08 33.4 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 AEO56092.1 - 0.11 11.1 0.1 0.15 10.6 0.1 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF2614 PF11023.3 AEO56093.1 - 0.05 13.3 0.1 0.93 9.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2614) HCV_NS4a PF01006.15 AEO56093.1 - 1.8 8.1 5.6 0.3 10.6 0.7 2.1 2 0 0 2 2 2 0 Hepatitis C virus non-structural protein NS4a MFS_1 PF07690.11 AEO56094.1 - 1.3e-30 106.3 31.2 1.3e-30 106.3 21.7 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 AEO56094.1 - 0.0003 20.3 1.3 0.0003 20.3 0.9 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.19 AEO56094.1 - 0.01 14.4 19.7 0.069 11.7 2.1 2.4 2 1 0 2 2 2 0 Sugar (and other) transporter PALP PF00291.20 AEO56095.1 - 5.3e-33 114.5 0.2 6.4e-33 114.2 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme zf-C2H2_4 PF13894.1 AEO56096.1 - 5.3e-07 29.5 10.9 0.031 14.6 1.9 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 AEO56096.1 - 1e-05 25.5 11.0 0.034 14.4 1.8 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type DUF3450 PF11932.3 AEO56096.1 - 0.013 14.7 3.3 0.019 14.2 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Atg14 PF10186.4 AEO56096.1 - 0.015 14.2 0.4 0.022 13.7 0.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 HALZ PF02183.13 AEO56096.1 - 0.016 14.8 0.5 0.034 13.8 0.4 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper PMSI1 PF15322.1 AEO56096.1 - 0.028 13.5 6.9 0.1 11.6 1.9 2.2 2 0 0 2 2 2 0 Protein missing in infertile sperm 1, putative V_ATPase_I PF01496.14 AEO56096.1 - 0.04 11.7 0.8 0.05 11.4 0.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_DNA_bd PF12329.3 AEO56096.1 - 0.3 10.9 7.6 0.51 10.1 5.3 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding APG6 PF04111.7 AEO56096.1 - 0.39 9.7 4.0 0.53 9.2 2.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Abhydrolase_5 PF12695.2 AEO56097.1 - 1.4e-05 24.9 0.0 2.5e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AEO56097.1 - 1.6e-05 24.9 0.5 2.9e-05 24.0 0.1 1.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family DUF218 PF02698.12 AEO56098.1 - 2.1e-07 30.5 0.2 1.4e-06 27.8 0.1 2.2 1 1 0 1 1 1 1 DUF218 domain Mur_ligase_M PF08245.7 AEO56099.1 - 8.3e-07 29.2 0.0 1.6e-06 28.2 0.0 1.6 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 AEO56099.1 - 0.0015 18.5 0.0 0.0027 17.7 0.0 1.4 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain Pkinase PF00069.20 AEO56101.1 - 3.5e-41 141.0 0.0 8.6e-41 139.7 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO56101.1 - 4e-28 98.1 0.0 7.6e-28 97.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO56101.1 - 0.0034 16.4 0.0 0.0056 15.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Ric8 PF10165.4 AEO56101.1 - 0.064 12.0 0.3 5.5 5.7 0.2 2.2 2 0 0 2 2 2 0 Guanine nucleotide exchange factor synembryn DUF2321 PF10083.4 AEO56101.1 - 0.24 10.8 0.1 0.5 9.8 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) MtrA PF04208.9 AEO56101.1 - 0.24 10.8 0.0 0.48 9.8 0.0 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit A L_HGMIC_fpl PF10242.4 AEO56102.1 - 2.2e-05 24.5 1.2 3.1e-05 24.0 0.8 1.2 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Claudin_2 PF13903.1 AEO56102.1 - 0.00015 21.4 3.9 0.00042 20.0 2.2 1.9 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF1109 PF06532.6 AEO56102.1 - 8.8 5.6 14.5 1.4 8.3 5.7 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1109) ERG4_ERG24 PF01222.12 AEO56103.1 - 2.5e-137 457.9 20.8 3.1e-137 457.6 14.4 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ATP-synt_C PF00137.16 AEO56104.1 - 9.1e-31 105.5 32.2 1.7e-18 66.2 9.6 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Flavi_NS4A PF01350.12 AEO56104.1 - 0.14 11.6 3.4 0.07 12.6 0.3 1.8 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A Ribosomal_L7Ae PF01248.21 AEO56105.1 - 8.8e-26 89.2 0.1 1e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 AEO56105.1 - 0.00038 20.3 0.2 0.002 17.9 0.1 1.8 1 1 0 1 1 1 1 RNase P subunit Pop3 Syja_N PF02383.13 AEO56106.1 - 8.8e-97 323.6 0.0 1.2e-96 323.2 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 AEO56106.1 - 1.1e-35 121.4 0.0 2e-35 120.6 0.0 1.4 1 0 0 1 1 1 1 Inositol phosphatase Fn_bind PF02986.9 AEO56106.1 - 0.041 13.3 0.1 0.64 9.5 0.0 2.3 2 0 0 2 2 2 0 Fibronectin binding repeat DUF3115 PF11312.3 AEO56107.1 - 1.5e-95 319.6 0.0 1.8e-95 319.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) Transketolase_N PF00456.16 AEO56108.1 - 6.8e-155 514.9 0.0 9e-155 514.5 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 AEO56108.1 - 2.3e-45 154.2 0.0 3.6e-45 153.6 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 AEO56108.1 - 2e-14 53.5 0.0 4.1e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 AEO56108.1 - 3.9e-05 22.7 0.0 0.00047 19.1 0.0 2.0 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 AEO56108.1 - 0.0011 17.7 0.0 0.0019 16.9 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Filament PF00038.16 AEO56109.1 - 0.001 18.6 22.3 0.0016 17.9 8.5 4.5 2 1 3 5 5 5 2 Intermediate filament protein TMF_DNA_bd PF12329.3 AEO56109.1 - 0.031 14.0 1.1 0.031 14.0 0.8 7.1 5 1 1 7 7 7 0 TATA element modulatory factor 1 DNA binding Reo_sigmaC PF04582.7 AEO56109.1 - 0.035 13.2 7.1 0.63 9.1 4.1 2.5 1 1 2 3 3 3 0 Reovirus sigma C capsid protein TSC22 PF01166.13 AEO56109.1 - 0.064 13.2 0.1 0.064 13.2 0.0 4.8 6 0 0 6 6 6 0 TSC-22/dip/bun family CCDC92 PF14916.1 AEO56109.1 - 0.49 10.0 0.0 0.49 10.0 0.0 5.0 7 0 0 7 7 7 0 Coiled-coil domain of unknown function MHC2-interact PF09307.5 AEO56109.1 - 0.65 9.7 5.6 0.65 9.7 0.5 3.4 2 1 1 3 3 3 0 CLIP, MHC2 interacting COG5 PF10392.4 AEO56109.1 - 2.1 8.2 10.8 0.068 13.1 1.1 3.0 2 1 1 3 3 3 0 Golgi transport complex subunit 5 V_ATPase_I PF01496.14 AEO56109.1 - 4.4 5.0 20.0 3.2 5.4 12.2 1.9 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family M_domain PF12938.2 AEO56109.1 - 4.7 6.9 9.6 0.56 9.9 1.0 3.3 2 1 0 3 3 3 0 M domain of GW182 DUF4521 PF15021.1 AEO56110.1 - 0.097 12.2 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4521) DUF2396 PF09654.5 AEO56110.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2396) Abhydrolase_2 PF02230.11 AEO56111.1 - 1.3e-07 31.2 0.0 0.1 12.0 0.0 3.1 2 1 1 3 3 3 3 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 AEO56111.1 - 2.3e-07 30.6 1.3 8.5e-07 28.8 0.4 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.8 AEO56111.1 - 0.00058 19.3 0.0 0.0017 17.8 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 AEO56111.1 - 0.019 14.8 16.8 3.2 7.5 11.7 2.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family FAA_hydrolase PF01557.13 AEO56111.1 - 0.023 14.1 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 Fumarylacetoacetate (FAA) hydrolase family Hydrolase_4 PF12146.3 AEO56111.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase LCCL PF03815.14 AEO56112.1 - 1.2e-18 66.8 0.1 2.3e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 LCCL domain TGT PF01702.13 AEO56113.1 - 3.9e-33 114.7 0.0 5.2e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Adaptin_N PF01602.15 AEO56114.1 - 2.5e-30 105.3 0.0 3.7e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region DUF4456 PF14644.1 AEO56115.1 - 0.097 11.8 0.0 0.097 11.8 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) TPR_11 PF13414.1 AEO56116.1 - 6.9e-11 41.6 2.1 5e-05 22.8 0.0 4.1 2 1 3 5 5 5 3 TPR repeat TPR_19 PF14559.1 AEO56116.1 - 1.4e-10 41.3 1.3 0.00014 22.0 0.1 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 AEO56116.1 - 5.7e-09 35.2 0.7 0.00011 21.8 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 AEO56116.1 - 2e-07 31.4 12.4 2.4e-06 28.0 0.0 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 AEO56116.1 - 6.7e-06 26.2 13.2 0.013 16.0 0.1 5.6 4 2 4 8 8 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 AEO56116.1 - 2e-05 24.0 0.0 0.0096 15.6 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 AEO56116.1 - 0.00012 21.9 0.4 0.024 14.8 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 AEO56116.1 - 0.0052 16.6 4.9 0.19 11.6 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 AEO56116.1 - 0.018 15.4 2.4 17 6.1 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.1 AEO56116.1 - 0.02 14.9 2.1 0.58 10.3 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 AEO56116.1 - 0.047 13.3 1.3 0.42 10.3 0.0 3.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 AEO56116.1 - 0.051 13.4 3.3 18 5.2 0.0 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat SRP54_N PF02881.14 AEO56116.1 - 0.069 13.2 0.2 0.16 12.1 0.1 1.6 1 0 0 1 1 1 0 SRP54-type protein, helical bundle domain PPR_3 PF13812.1 AEO56116.1 - 0.092 13.0 0.0 0.42 11.0 0.0 2.2 1 0 0 1 1 1 0 Pentatricopeptide repeat domain TPR_7 PF13176.1 AEO56116.1 - 0.12 12.2 1.3 4.5 7.3 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Polyketide_cyc PF03364.15 AEO56118.1 - 2.1e-33 115.0 0.0 3.7e-33 114.2 0.0 1.4 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 AEO56118.1 - 0.004 17.3 12.6 0.42 10.7 8.7 2.3 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport CN_hydrolase PF00795.17 AEO56119.1 - 6.3e-26 90.8 0.0 1.1e-25 90.0 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 AEO56119.1 - 7.9e-14 51.1 0.0 3.4e-08 32.6 0.0 2.8 2 1 0 2 2 2 2 NAD synthase Methyltransf_12 PF08242.7 AEO56120.1 - 1.2e-14 54.6 0.0 3e-14 53.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO56120.1 - 3.8e-12 46.5 0.0 8.4e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO56120.1 - 1.6e-10 41.1 0.0 3.3e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO56120.1 - 1.4e-09 37.8 0.0 3.5e-09 36.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO56120.1 - 2.1e-09 37.1 0.0 3.5e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO56120.1 - 5.6e-09 36.5 0.1 2.2e-08 34.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 AEO56120.1 - 1.4e-07 30.8 0.0 2.1e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 AEO56120.1 - 0.00015 21.7 0.0 0.00027 20.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AEO56120.1 - 0.0018 17.6 0.0 0.0035 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain DUF3419 PF11899.3 AEO56120.1 - 0.0021 16.8 0.0 0.003 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_24 PF13578.1 AEO56120.1 - 0.0032 18.2 0.0 0.0076 17.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 AEO56120.1 - 0.0039 16.8 0.0 0.012 15.2 0.0 1.9 1 1 0 1 1 1 1 Hypothetical methyltransferase NNMT_PNMT_TEMT PF01234.12 AEO56120.1 - 0.018 14.0 0.0 3.5 6.5 0.0 2.3 1 1 1 2 2 2 0 NNMT/PNMT/TEMT family SAC3_GANP PF03399.11 AEO56121.1 - 4.1e-43 147.3 0.1 6e-43 146.7 0.0 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 AEO56121.1 - 0.0023 17.6 0.0 0.005 16.6 0.0 1.5 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Mis12 PF05859.7 AEO56121.1 - 0.54 10.0 3.5 1.3 8.8 2.4 1.6 1 0 0 1 1 1 0 Mis12 protein Podoplanin PF05808.6 AEO56122.1 - 0.3 10.6 3.2 0.44 10.1 0.0 2.3 2 0 0 2 2 2 0 Podoplanin SOG2 PF10428.4 AEO56122.1 - 1.7 7.1 7.2 2.6 6.5 5.0 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DKCLD PF08068.7 AEO56124.1 - 2.1e-30 104.4 0.2 1.2e-29 102.0 0.1 2.3 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 AEO56124.1 - 8.1e-24 84.4 0.2 5.4e-21 75.3 0.1 3.3 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 AEO56124.1 - 3.1e-22 78.0 0.5 6.1e-22 77.1 0.3 1.5 1 0 0 1 1 1 1 PUA domain PAT1 PF09770.4 AEO56125.1 - 3.4 5.8 12.9 4.1 5.5 8.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 AEO56125.1 - 6.1 6.1 15.3 8.5 5.6 10.6 1.1 1 0 0 1 1 1 0 Vta1 like CN_hydrolase PF00795.17 AEO56126.1 - 1.7e-11 43.8 0.0 3.3e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase CN_hydrolase PF00795.17 AEO56128.1 - 0.037 13.3 0.0 0.15 11.3 0.0 1.9 2 1 0 2 2 2 0 Carbon-nitrogen hydrolase CD99L2 PF12301.3 AEO56131.1 - 0.1 12.2 0.0 0.1 12.2 0.0 3.2 3 0 0 3 3 3 0 CD99 antigen like protein 2 Serglycin PF04360.7 AEO56131.1 - 1.5 8.5 7.7 3 7.5 5.3 1.5 1 0 0 1 1 1 0 Serglycin DER1 PF04511.10 AEO56132.1 - 1.3e-23 83.5 1.0 1.5e-23 83.3 0.7 1.0 1 0 0 1 1 1 1 Der1-like family DUF2269 PF10027.4 AEO56132.1 - 0.048 13.4 0.4 0.13 12.0 0.2 1.7 1 1 0 1 1 1 0 Predicted integral membrane protein (DUF2269) ArgJ PF01960.13 AEO56133.1 - 3e-148 493.3 0.1 3.4e-148 493.1 0.1 1.0 1 0 0 1 1 1 1 ArgJ family Rep_fac_C PF08542.6 AEO56134.1 - 2.8e-20 72.1 0.0 5.5e-20 71.1 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.24 AEO56134.1 - 3.7e-12 46.5 0.0 7.2e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 AEO56134.1 - 1.7e-11 44.0 0.0 1.4e-09 37.8 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.1 AEO56134.1 - 1.5e-07 31.3 0.0 3.5e-07 30.1 0.0 1.6 1 1 1 2 2 1 1 AAA domain AAA_16 PF13191.1 AEO56134.1 - 4.9e-06 26.6 0.1 0.00018 21.5 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 AEO56134.1 - 8.2e-06 25.9 0.1 0.0017 18.5 0.1 2.8 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 AEO56134.1 - 1.4e-05 24.2 0.0 4.3e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Viral_helicase1 PF01443.13 AEO56134.1 - 7.6e-05 22.3 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Rad17 PF03215.10 AEO56134.1 - 0.00011 21.0 0.0 0.077 11.6 0.0 2.7 2 1 1 3 3 3 2 Rad17 cell cycle checkpoint protein AAA_3 PF07726.6 AEO56134.1 - 0.00015 21.3 0.0 0.0003 20.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 AEO56134.1 - 0.00038 20.0 0.1 0.073 12.4 0.0 2.3 1 1 1 2 2 2 1 AAA-like domain Mg_chelatase PF01078.16 AEO56134.1 - 0.0016 17.6 0.0 0.021 13.9 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 AEO56134.1 - 0.0018 17.9 0.0 0.0037 16.9 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain DNA_pol3_delta PF06144.8 AEO56134.1 - 0.0022 17.5 0.1 0.0038 16.7 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DNA_pol3_gamma3 PF12169.3 AEO56134.1 - 0.0057 16.4 0.3 0.32 10.7 0.0 2.7 3 0 0 3 3 2 1 DNA polymerase III subunits gamma and tau domain III NTPase_1 PF03266.10 AEO56134.1 - 0.008 15.8 0.5 0.053 13.2 0.1 2.3 2 1 1 3 3 2 1 NTPase AAA_25 PF13481.1 AEO56134.1 - 0.011 15.1 0.1 0.16 11.3 0.0 2.4 1 1 1 2 2 2 0 AAA domain DEAD PF00270.24 AEO56134.1 - 0.013 15.0 0.1 0.17 11.3 0.0 2.3 1 1 1 2 2 2 0 DEAD/DEAH box helicase KTI12 PF08433.5 AEO56134.1 - 0.017 14.3 0.0 0.03 13.5 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_31 PF13614.1 AEO56134.1 - 0.02 14.8 0.0 0.059 13.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 AEO56134.1 - 0.022 13.5 0.0 0.044 12.5 0.0 1.5 1 0 0 1 1 1 0 ArgK protein AAA_11 PF13086.1 AEO56134.1 - 0.025 14.1 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 AEO56134.1 - 0.034 13.6 0.0 0.07 12.5 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_5 PF07728.9 AEO56134.1 - 0.052 13.2 0.1 0.22 11.2 0.1 2.0 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 AEO56134.1 - 0.08 13.2 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain IGPD PF00475.13 AEO56135.1 - 1.5e-60 203.2 0.2 2.4e-60 202.6 0.2 1.3 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Skp1 PF01466.14 AEO56136.1 - 0.61 10.1 4.2 1.2 9.2 2.9 1.5 1 0 0 1 1 1 0 Skp1 family, dimerisation domain RR_TM4-6 PF06459.7 AEO56136.1 - 0.79 9.5 14.6 1.2 9.0 10.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4554 PF15091.1 AEO56136.1 - 2.4 6.8 7.3 3.1 6.4 5.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) Abhydrolase_1 PF00561.15 AEO56137.1 - 4.3e-14 52.6 0.0 6.1e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 AEO56137.1 - 1.9e-10 41.0 0.0 3.5e-10 40.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO56137.1 - 5.3e-05 23.0 0.0 0.00029 20.6 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Cutinase PF01083.17 AEO56137.1 - 0.0037 17.0 0.0 0.0066 16.2 0.0 1.5 1 0 0 1 1 1 1 Cutinase DUF915 PF06028.6 AEO56137.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Cohesin_load PF10345.4 AEO56138.1 - 5e-175 583.2 3.6 5.9e-175 582.9 2.5 1.1 1 0 0 1 1 1 1 Cohesin loading factor Metal_resist PF13801.1 AEO56139.1 - 0.013 15.4 0.4 0.041 13.8 0.1 1.9 2 0 0 2 2 2 0 Heavy-metal resistance SR-25 PF10500.4 AEO56139.1 - 3.5 7.0 14.6 2.3 7.6 1.6 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Rhomboid PF01694.17 AEO56140.1 - 1.6e-32 112.5 10.3 1.6e-32 112.5 7.2 1.9 2 0 0 2 2 2 1 Rhomboid family Pet127 PF08634.5 AEO56141.1 - 7.3e-122 405.7 1.5 1.1e-121 405.2 1.0 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 zf-C4H2 PF10146.4 AEO56142.1 - 0.0016 18.5 0.8 0.0016 18.5 0.5 1.5 2 0 0 2 2 1 1 Zinc finger-containing protein Tropomyosin PF00261.15 AEO56142.1 - 0.032 13.3 22.9 0.14 11.2 5.2 2.1 1 1 1 2 2 2 0 Tropomyosin KcnmB2_inactiv PF09303.5 AEO56142.1 - 0.033 13.9 1.7 0.1 12.4 1.2 1.8 1 0 0 1 1 1 0 KCNMB2, ball and chain domain DUF3015 PF11220.3 AEO56142.1 - 0.063 12.8 0.0 0.65 9.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3015) IncA PF04156.9 AEO56142.1 - 0.071 12.7 19.4 0.12 11.9 13.4 1.3 1 0 0 1 1 1 0 IncA protein Exonuc_VII_L PF02601.10 AEO56142.1 - 0.2 10.8 7.7 0.33 10.1 5.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3373 PF11853.3 AEO56142.1 - 0.34 9.3 1.3 0.51 8.8 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Tropomyosin_1 PF12718.2 AEO56142.1 - 0.73 9.6 24.8 1.2 9.0 5.7 2.3 1 1 1 2 2 2 0 Tropomyosin like DUF2937 PF11157.3 AEO56142.1 - 0.9 8.8 3.6 3.4 6.9 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) YPEB PF14620.1 AEO56142.1 - 1.4 7.8 6.5 4.3 6.2 4.5 1.7 1 1 0 1 1 1 0 YpeB sporulation OEP PF02321.13 AEO56142.1 - 2.6 7.5 11.0 0.26 10.8 2.3 2.5 1 1 1 2 2 2 0 Outer membrane efflux protein LXG PF04740.7 AEO56142.1 - 3.7 7.2 8.2 7.1 6.3 5.7 1.4 1 0 0 1 1 1 0 LXG domain of WXG superfamily DUF4279 PF14106.1 AEO56142.1 - 5.1 7.0 9.8 1 9.2 0.7 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4279) Phasin PF05597.6 AEO56142.1 - 5.1 6.8 10.1 23 4.7 0.4 3.2 2 1 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Occludin_ELL PF07303.8 AEO56142.1 - 5.1 7.8 7.9 80 4.0 4.8 2.5 1 1 0 1 1 1 0 Occludin homology domain IFT57 PF10498.4 AEO56142.1 - 5.7 5.5 12.3 3.2 6.3 6.8 1.6 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Period_C PF12114.3 AEO56142.1 - 8.1 5.9 24.6 7.3 6.1 12.1 2.4 2 0 0 2 2 2 0 Period protein 2/3C-terminal region EMP24_GP25L PF01105.19 AEO56142.1 - 9.4 5.9 11.1 4.9 6.8 1.2 2.8 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF1664 PF07889.7 AEO56142.1 - 9.6 6.0 6.8 19 5.0 1.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF2414 PF10309.4 AEO56143.1 - 1.7e-20 72.4 0.0 3e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) DUF3934 PF13070.1 AEO56145.1 - 8.5 6.6 7.5 19 5.5 3.6 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3934) Myb_DNA-binding PF00249.26 AEO56146.1 - 3.2e-20 71.9 1.9 1.6e-09 37.6 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 AEO56146.1 - 2.1e-17 62.9 1.1 9.9e-11 41.5 0.0 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain DUF3523 PF12037.3 AEO56146.1 - 0.033 13.1 9.2 0.045 12.7 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) HTH_Tnp_1 PF01527.15 AEO56146.1 - 0.037 13.9 1.9 0.1 12.5 1.3 1.7 1 0 0 1 1 1 0 Transposase DUF3306 PF11748.3 AEO56146.1 - 0.16 12.5 7.0 0.34 11.5 4.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) SelP_N PF04592.9 AEO56146.1 - 0.43 9.9 12.4 0.64 9.3 8.6 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region BAF1_ABF1 PF04684.8 AEO56146.1 - 0.74 8.5 27.1 1 8.1 18.8 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Zip PF02535.17 AEO56146.1 - 1.3 7.9 8.0 1.9 7.4 5.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Suf PF05843.9 AEO56146.1 - 3.6 7.2 10.3 5.2 6.7 7.2 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Glyco_transf_41 PF13844.1 AEO56148.1 - 4.4e-98 328.2 0.0 4e-49 166.8 0.0 3.1 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_1 PF00515.23 AEO56148.1 - 2.2e-26 90.3 0.1 4.9e-05 22.7 0.0 7.0 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.1 AEO56148.1 - 1.4e-25 88.6 2.6 2.3e-08 33.5 0.0 5.4 5 0 0 5 5 5 3 TPR repeat TPR_2 PF07719.12 AEO56148.1 - 6.7e-22 75.5 0.3 0.0023 17.7 0.0 7.3 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 AEO56148.1 - 3.4e-17 62.1 0.6 1.9e-07 30.8 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 AEO56148.1 - 5.4e-15 53.9 0.0 0.014 15.1 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 AEO56148.1 - 1.4e-14 52.9 0.1 0.0014 18.6 0.0 5.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 AEO56148.1 - 1.4e-11 44.7 9.0 0.016 15.8 0.0 6.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 AEO56148.1 - 2.7e-11 43.0 11.4 0.00083 19.7 0.1 7.0 5 2 2 7 7 5 4 Tetratricopeptide repeat TPR_10 PF13374.1 AEO56148.1 - 8.9e-09 35.0 12.1 0.13 12.2 0.2 7.0 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 AEO56148.1 - 2e-08 34.4 0.8 0.008 16.4 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 AEO56148.1 - 1.7e-06 27.3 9.0 0.071 12.9 0.0 6.3 8 0 0 8 8 7 2 Tetratricopeptide repeat Apc3 PF12895.2 AEO56148.1 - 2.5e-05 24.3 1.2 0.01 15.9 0.0 3.9 4 1 0 4 4 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 AEO56148.1 - 3.6e-05 23.9 0.5 4.3 8.0 0.1 5.6 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.1 AEO56148.1 - 0.0061 16.3 3.3 1.6 8.6 0.0 3.6 3 1 1 4 4 3 1 Tetratricopeptide repeat BTAD PF03704.12 AEO56148.1 - 0.026 14.8 6.2 3.9 7.7 0.0 3.5 3 0 0 3 3 3 0 Bacterial transcriptional activator domain TPR_5 PF12688.2 AEO56148.1 - 0.081 12.9 1.5 0.64 10.0 0.0 3.1 4 0 0 4 4 4 0 Tetratrico peptide repeat KSR1-SAM PF13543.1 AEO56148.1 - 0.092 12.5 0.2 4.8 6.9 0.0 2.5 1 1 1 2 2 2 0 SAM like domain present in kinase suppressor RAS 1 Sel1 PF08238.7 AEO56148.1 - 1.8 9.2 8.1 2.6 8.7 0.1 4.0 5 0 0 5 5 3 0 Sel1 repeat Ribosomal_L11_N PF03946.9 AEO56149.1 - 4.1e-18 64.5 0.1 6.6e-18 63.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 AEO56149.1 - 3e-10 40.0 0.1 5.1e-10 39.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain IF2_N PF04760.10 AEO56149.1 - 0.015 14.9 0.1 0.23 11.1 0.0 2.4 1 1 1 2 2 2 0 Translation initiation factor IF-2, N-terminal region Sec23_trunk PF04811.10 AEO56150.1 - 4.8e-81 271.7 0.0 6.6e-81 271.2 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 AEO56150.1 - 9.6e-35 118.1 1.6 1.7e-34 117.3 0.3 2.1 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 AEO56150.1 - 5.7e-32 110.0 0.2 1.3e-31 108.9 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 AEO56150.1 - 3.1e-16 58.6 6.5 6.4e-16 57.6 4.5 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 AEO56150.1 - 3.9e-14 52.0 0.0 8.1e-14 51.0 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Kelch_1 PF01344.20 AEO56151.1 - 0.0084 15.6 0.4 0.012 15.1 0.1 1.5 2 0 0 2 2 2 1 Kelch motif Kelch_2 PF07646.10 AEO56151.1 - 0.032 14.0 0.0 0.06 13.1 0.0 1.5 1 0 0 1 1 1 0 Kelch motif Kelch_5 PF13854.1 AEO56151.1 - 0.095 12.6 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 Kelch motif Kelch_5 PF13854.1 AEO56152.1 - 1.4e-07 31.3 4.2 2e-06 27.6 0.2 3.0 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 AEO56152.1 - 0.00045 19.8 2.7 0.027 14.2 0.0 3.2 3 1 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 AEO56152.1 - 2.5 8.4 8.7 22 5.4 0.0 4.0 3 1 1 4 4 4 0 Kelch motif MAPEG PF01124.13 AEO56154.1 - 1.5e-26 92.5 1.1 1.7e-26 92.3 0.8 1.0 1 0 0 1 1 1 1 MAPEG family DNA_pol_lambd_f PF10391.4 AEO56155.1 - 1.4e-22 79.0 1.1 2.7e-22 78.0 0.8 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.1 AEO56155.1 - 9.6e-22 76.4 0.1 2.4e-21 75.1 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 AEO56155.1 - 2.5e-21 75.8 0.0 4.8e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.1 AEO56155.1 - 2.7e-10 40.2 0.1 6.3e-10 39.1 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_5 PF14520.1 AEO56155.1 - 0.026 14.6 0.0 0.12 12.5 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix domain TFIIE_alpha PF02002.12 AEO56156.1 - 3.5e-15 55.3 0.2 6e-15 54.6 0.2 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit RRN7 PF11781.3 AEO56156.1 - 0.013 14.9 2.9 1.4 8.4 0.1 2.3 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zinc_ribbon_5 PF13719.1 AEO56156.1 - 0.024 14.2 0.9 5.5 6.6 0.0 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 AEO56156.1 - 0.036 13.7 0.7 4.9 6.9 0.0 2.7 2 0 0 2 2 2 0 zinc-ribbon domain SnAC PF14619.1 AEO56156.1 - 0.041 14.0 0.4 0.11 12.7 0.3 1.7 1 0 0 1 1 1 0 Snf2-ATP coupling, chromatin remodelling complex zf-HIT PF04438.11 AEO56156.1 - 0.045 13.3 0.9 1.5 8.5 0.2 2.3 2 0 0 2 2 2 0 HIT zinc finger Elf1 PF05129.8 AEO56156.1 - 0.068 12.8 0.1 0.16 11.7 0.1 1.6 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-FPG_IleRS PF06827.9 AEO56156.1 - 0.14 11.8 1.6 3.4 7.4 0.0 2.4 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Zn-ribbon_8 PF09723.5 AEO56156.1 - 0.18 11.7 1.6 0.88 9.5 0.9 2.3 1 1 1 2 2 2 0 Zinc ribbon domain TF_Zn_Ribbon PF08271.7 AEO56156.1 - 0.19 11.0 2.2 1.1 8.6 1.5 2.1 1 1 1 2 2 2 0 TFIIB zinc-binding SMC_N PF02463.14 AEO56157.1 - 5.6e-42 143.4 0.0 2.9e-41 141.1 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 AEO56157.1 - 1.7e-27 95.7 0.0 8.1e-27 93.5 0.0 2.3 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain Reo_sigmaC PF04582.7 AEO56157.1 - 1.1e-07 31.3 19.5 0.026 13.7 1.0 5.1 4 1 1 5 5 5 4 Reovirus sigma C capsid protein AAA_21 PF13304.1 AEO56157.1 - 5.9e-06 26.4 0.6 5.9e-06 26.4 0.4 2.9 3 1 0 3 3 3 1 AAA domain DUF3584 PF12128.3 AEO56157.1 - 0.00041 17.8 38.8 0.00041 17.8 26.9 5.0 2 2 3 5 5 5 2 Protein of unknown function (DUF3584) AAA_13 PF13166.1 AEO56157.1 - 0.0025 16.3 96.6 0.065 11.7 15.0 6.0 3 2 1 5 5 5 4 AAA domain SbcCD_C PF13558.1 AEO56157.1 - 0.0029 17.5 0.0 0.022 14.6 0.0 2.7 2 0 0 2 2 1 1 Putative exonuclease SbcCD, C subunit DUF3552 PF12072.3 AEO56157.1 - 0.0056 15.9 8.8 0.0056 15.9 6.1 7.7 4 2 4 8 8 6 1 Domain of unknown function (DUF3552) Spc7 PF08317.6 AEO56157.1 - 0.03 12.9 108.6 0.091 11.4 1.6 7.1 3 2 4 7 7 7 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.7 AEO56157.1 - 1 9.1 29.8 0.84 9.4 0.0 7.3 5 2 2 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3592 PF12158.3 AEO56157.1 - 1.8 8.3 3.0 3.2 7.5 1.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3592) DUF948 PF06103.6 AEO56157.1 - 6.8 6.6 27.7 0.06 13.2 0.5 5.7 5 1 1 6 6 6 0 Bacterial protein of unknown function (DUF948) Tropomyosin_1 PF12718.2 AEO56157.1 - 9.4 6.0 115.7 0.47 10.2 13.7 7.6 4 2 1 6 6 6 0 Tropomyosin like DUF2838 PF10998.3 AEO56158.1 - 3.4e-48 162.1 9.7 3.4e-48 162.1 6.7 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF2838) DinB_2 PF12867.2 AEO56158.1 - 0.031 14.6 0.1 2.2 8.6 0.0 2.4 2 0 0 2 2 2 0 DinB superfamily Atg14 PF10186.4 AEO56158.1 - 0.14 11.1 1.3 0.2 10.5 0.9 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 WD40 PF00400.27 AEO56159.1 - 3.3e-37 125.0 6.5 2.1e-08 33.7 0.1 5.6 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 AEO56159.1 - 1.9e-07 30.9 0.1 0.018 14.7 0.0 2.7 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A DCX PF03607.12 AEO56159.1 - 0.041 13.4 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 Doublecortin Pribosyltran_N PF13793.1 AEO56160.1 - 1.1e-26 92.8 0.0 2e-26 92.0 0.0 1.6 1 1 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Orn_Arg_deC_N PF02784.11 AEO56161.1 - 3.1e-78 262.4 0.0 4.2e-78 261.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 AEO56161.1 - 1.7e-30 105.1 0.1 3.7e-30 104.0 0.0 1.6 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain M16C_assoc PF08367.6 AEO56162.1 - 1.9e-58 197.2 0.1 2.8e-58 196.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 AEO56162.1 - 5.1e-37 127.3 0.0 2.3e-21 76.3 0.0 3.7 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 AEO56162.1 - 1.1e-07 31.7 0.0 1.1e-06 28.5 0.0 2.4 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) HHH_8 PF14716.1 AEO56162.1 - 0.064 13.4 0.0 0.47 10.6 0.0 2.4 3 0 0 3 3 3 0 Helix-hairpin-helix domain Taxilin PF09728.4 AEO56163.1 - 5.3e-93 311.5 62.3 6.9e-93 311.1 43.2 1.1 1 0 0 1 1 1 1 Myosin-like coiled-coil protein DUF904 PF06005.7 AEO56163.1 - 0.004 17.4 8.9 0.004 17.4 6.2 5.7 2 2 3 5 5 5 1 Protein of unknown function (DUF904) bZIP_2 PF07716.10 AEO56163.1 - 0.024 14.4 2.4 0.024 14.4 1.6 5.7 6 0 0 6 6 6 0 Basic region leucine zipper TMF_TATA_bd PF12325.3 AEO56163.1 - 0.19 11.4 58.6 2.6 7.8 10.5 5.0 2 2 2 4 4 4 0 TATA element modulatory factor 1 TATA binding MCPsignal PF00015.16 AEO56163.1 - 9.2 5.7 14.0 0.65 9.4 2.4 2.8 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Daxx PF03344.10 AEO56164.1 - 1.8 6.9 19.9 2.6 6.4 13.8 1.3 1 0 0 1 1 1 0 Daxx Family NMO PF03060.10 AEO56165.1 - 5.2e-71 239.4 0.9 6.3e-71 239.2 0.6 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 AEO56165.1 - 2.2e-06 26.8 0.0 0.0008 18.3 0.0 2.4 2 1 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 AEO56165.1 - 0.065 12.0 6.1 0.14 11.0 4.2 1.5 1 0 0 1 1 1 0 FMN-dependent dehydrogenase SSP160 PF06933.6 AEO56165.1 - 1.9 6.3 14.6 2.5 5.9 10.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Acetyltransf_1 PF00583.19 AEO56166.1 - 1.4e-17 63.5 0.0 1.8e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AEO56166.1 - 2.1e-07 30.9 0.1 4.2e-07 30.0 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 AEO56166.1 - 5.7e-07 29.2 0.0 9e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 AEO56166.1 - 2e-06 27.7 0.1 2.8e-06 27.2 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 AEO56166.1 - 2.2e-06 27.7 0.0 3.1e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 AEO56166.1 - 2.2e-05 24.4 0.0 4.7e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 AEO56166.1 - 8.9e-05 22.3 0.0 0.00011 22.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain MarR_2 PF12802.2 AEO56167.1 - 0.022 14.4 1.1 0.05 13.2 0.7 1.6 1 0 0 1 1 1 0 MarR family Peptidase_M16_C PF05193.16 AEO56168.1 - 5.9e-20 71.7 0.0 6.3e-14 52.0 0.0 3.3 3 1 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 AEO56168.1 - 5.9e-05 22.8 0.0 0.00013 21.7 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Sporozoite_P67 PF05642.6 AEO56168.1 - 0.0032 15.4 3.0 0.0047 14.8 2.1 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Nucleoplasmin PF03066.10 AEO56168.1 - 0.46 9.9 7.5 0.95 8.9 5.2 1.5 1 0 0 1 1 1 0 Nucleoplasmin Ribosomal_L36e PF01158.13 AEO56170.1 - 2.2e-40 136.5 5.2 2.5e-40 136.3 3.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e LemA PF04011.7 AEO56170.1 - 0.015 14.3 0.1 0.018 14.1 0.0 1.1 1 0 0 1 1 1 0 LemA family MRP-L28 PF09812.4 AEO56170.1 - 0.035 13.9 1.2 0.041 13.6 0.8 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 ORC6 PF05460.8 AEO56170.1 - 0.056 12.5 0.4 0.065 12.3 0.3 1.0 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Dsl1_C PF11989.3 AEO56171.1 - 0.016 14.3 0.0 0.036 13.2 0.0 1.5 1 0 0 1 1 1 0 Retrograde transport protein Dsl1 C terminal Zw10 PF06248.8 AEO56171.1 - 0.063 11.4 0.0 0.23 9.5 0.0 1.7 2 0 0 2 2 2 0 Centromere/kinetochore Zw10 PI-PLC-X PF00388.14 AEO56174.1 - 2.4e-56 189.2 0.0 4.6e-56 188.2 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 AEO56174.1 - 1.4e-38 131.5 0.0 3e-38 130.4 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 AEO56174.1 - 5.1e-09 35.8 0.0 1.5e-08 34.3 0.0 1.8 1 0 0 1 1 1 1 C2 domain EF-hand_like PF09279.6 AEO56174.1 - 4.9e-05 23.2 0.0 0.00026 20.9 0.0 2.1 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like zf-DHHC PF01529.15 AEO56175.1 - 2.6e-43 147.3 9.6 2.6e-43 147.3 6.7 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase UQ_con PF00179.21 AEO56176.1 - 1e-20 73.6 0.1 2.1e-20 72.5 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme RWD PF05773.17 AEO56176.1 - 0.062 13.2 1.0 0.08 12.8 0.0 1.7 2 0 0 2 2 2 0 RWD domain PAT1 PF09770.4 AEO56176.1 - 1 7.4 20.0 1.3 7.1 13.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Suf PF05843.9 AEO56176.1 - 7.7 6.1 8.1 10 5.7 5.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Lin-8 PF03353.10 AEO56176.1 - 7.8 5.6 10.0 11 5.1 7.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist B-block_TFIIIC PF04182.7 AEO56177.1 - 3e-18 65.4 0.0 8.1e-17 60.8 0.0 2.8 3 0 0 3 3 3 1 B-block binding subunit of TFIIIC Haemadin PF09065.5 AEO56177.1 - 0.038 13.5 0.1 0.083 12.4 0.1 1.5 1 0 0 1 1 1 0 Haemadin Peptidase_C37 PF05416.7 AEO56178.1 - 0.092 11.0 4.4 0.17 10.1 3.1 1.5 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Cyanate_lyase PF02560.9 AEO56180.1 - 7.8e-33 111.8 0.0 1.1e-32 111.3 0.0 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.1 AEO56180.1 - 0.00025 21.2 1.3 0.00036 20.6 0.9 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 AEO56180.1 - 0.0015 17.9 0.1 0.0032 16.9 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_3 PF01381.17 AEO56180.1 - 0.0016 18.2 0.0 0.0026 17.5 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix Ebp2 PF05890.7 AEO56182.1 - 1.9e-91 306.1 21.5 1.9e-91 306.1 14.9 2.4 2 1 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 DUF1768 PF08719.6 AEO56182.1 - 0.0068 16.1 1.0 0.014 15.0 0.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) zf-MYND PF01753.13 AEO56183.1 - 6.7e-08 32.2 19.6 1.9e-07 30.7 13.6 1.8 1 0 0 1 1 1 1 MYND finger PHO4 PF01384.15 AEO56184.1 - 0.02 13.5 0.7 1.9 7.0 0.0 2.1 2 0 0 2 2 2 0 Phosphate transporter family FA_desaturase PF00487.19 AEO56184.1 - 0.081 12.3 2.3 0.11 11.8 1.6 1.1 1 0 0 1 1 1 0 Fatty acid desaturase DUF2956 PF11169.3 AEO56184.1 - 6.3 6.8 5.9 4.8 7.1 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) Cation_efflux PF01545.16 AEO56185.1 - 4.2e-22 78.5 12.5 2.1e-19 69.7 7.7 2.2 2 0 0 2 2 2 2 Cation efflux family GATase_4 PF13230.1 AEO56186.1 - 2.8e-19 68.8 0.0 3.1e-17 62.1 0.0 2.2 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 AEO56186.1 - 1.7e-08 34.5 0.0 2.8e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 AEO56186.1 - 9.6e-07 27.8 0.0 6.1e-05 21.8 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferases class-II Dynamin_N PF00350.18 AEO56187.1 - 5.5e-42 143.4 0.0 1.3e-41 142.2 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 AEO56187.1 - 2.5e-07 29.7 0.1 1e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 Dynamin central region AAA_16 PF13191.1 AEO56187.1 - 0.00065 19.7 0.8 0.051 13.5 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.18 AEO56187.1 - 0.0014 18.6 0.1 0.0071 16.3 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 AEO56187.1 - 0.0018 18.7 0.1 0.0092 16.4 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein STAT_int PF02865.12 AEO56187.1 - 0.038 13.9 0.6 0.27 11.2 0.2 2.5 2 0 0 2 2 2 0 STAT protein, protein interaction domain Peptidase_M4_C PF02868.10 AEO56187.1 - 0.04 13.6 0.1 0.099 12.3 0.1 1.6 1 0 0 1 1 1 0 Thermolysin metallopeptidase, alpha-helical domain AAA_21 PF13304.1 AEO56187.1 - 0.13 12.1 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain TRAP_alpha PF03896.11 AEO56188.1 - 0.00039 19.5 0.0 0.0011 18.0 0.0 1.7 2 0 0 2 2 2 1 Translocon-associated protein (TRAP), alpha subunit SMN PF06003.7 AEO56189.1 - 1.1 8.2 5.3 1.5 7.9 3.7 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Med5 PF08689.5 AEO56190.1 - 6.9e-270 897.9 0.0 2e-269 896.4 0.0 1.6 1 1 0 1 1 1 1 Mediator complex subunit Med5 Ribosomal_60s PF00428.14 AEO56190.1 - 2.2 8.7 11.8 22 5.5 5.3 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein Syndecan PF01034.15 AEO56191.1 - 0.0094 15.5 0.0 0.0094 15.5 0.0 1.7 2 0 0 2 2 2 1 Syndecan domain Podoplanin PF05808.6 AEO56191.1 - 0.016 14.7 0.6 0.028 13.9 0.4 1.3 1 0 0 1 1 1 0 Podoplanin CcmD PF04995.9 AEO56191.1 - 0.048 13.3 0.9 0.098 12.4 0.7 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) FMN_dh PF01070.13 AEO56192.1 - 3.4e-104 348.5 0.1 4.4e-104 348.1 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 AEO56192.1 - 4e-17 61.7 0.0 7.6e-17 60.8 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NMO PF03060.10 AEO56192.1 - 8.5e-06 25.1 0.3 1.9e-05 24.0 0.2 1.5 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.12 AEO56192.1 - 0.0016 17.4 1.8 0.0035 16.3 0.5 1.8 1 1 1 2 2 2 1 Conserved region in glutamate synthase PGA_cap PF09587.5 AEO56192.1 - 0.048 13.0 0.0 0.11 11.7 0.0 1.6 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap DHO_dh PF01180.16 AEO56192.1 - 0.05 12.5 0.1 5.5 5.8 0.0 2.3 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase IMPDH PF00478.20 AEO56192.1 - 1.2 7.8 7.9 0.3 9.9 0.3 3.0 3 1 1 4 4 4 0 IMP dehydrogenase / GMP reductase domain DUF3439 PF11921.3 AEO56192.1 - 1.5 8.5 12.7 3.2 7.5 8.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF4202 PF13875.1 AEO56193.1 - 4.5e-63 212.2 0.2 5.1e-63 212.0 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) PriCT_1 PF08708.6 AEO56193.1 - 0.022 14.5 0.1 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 Primase C terminal 1 (PriCT-1) 14-3-3 PF00244.15 AEO56194.1 - 2.7e-08 33.2 0.1 9.2e-08 31.4 0.0 1.7 2 0 0 2 2 2 1 14-3-3 protein Sterol-sensing PF12349.3 AEO56196.1 - 1.2e-36 125.4 9.0 1.2e-36 125.4 6.3 2.0 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 AEO56196.1 - 6.7e-12 44.1 1.2 9.1e-12 43.7 0.8 1.1 1 0 0 1 1 1 1 Patched family WD40 PF00400.27 AEO56196.1 - 0.019 14.8 0.0 0.066 13.1 0.0 2.0 1 0 0 1 1 1 0 WD domain, G-beta repeat Cupin_8 PF13621.1 AEO56197.1 - 6.2e-67 225.7 0.0 7.9e-67 225.3 0.0 1.0 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 AEO56197.1 - 2e-05 24.0 0.1 0.0066 15.7 0.0 2.2 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.17 AEO56197.1 - 0.018 15.2 0.0 0.35 11.1 0.0 2.4 2 0 0 2 2 2 0 JmjC domain, hydroxylase Spb1_C PF07780.7 AEO56198.1 - 9.7e-81 270.3 29.8 9.7e-81 270.3 20.7 4.0 3 2 1 4 4 4 1 Spb1 C-terminal domain DUF3381 PF11861.3 AEO56198.1 - 2.9e-56 189.3 11.4 2.9e-56 189.3 7.9 5.3 3 2 1 5 5 5 1 Domain of unknown function (DUF3381) FtsJ PF01728.14 AEO56198.1 - 8.6e-55 185.5 0.1 2.8e-54 183.8 0.0 1.9 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 AEO56198.1 - 0.047 14.2 0.2 5.4 7.6 0.0 2.8 2 0 0 2 2 2 0 Methyltransferase domain WD40 PF00400.27 AEO56199.1 - 4.7e-23 80.1 5.5 1.3e-05 24.8 0.0 6.3 7 0 0 7 7 7 4 WD domain, G-beta repeat EamA PF00892.15 AEO56200.1 - 2e-07 31.0 31.3 3.7e-07 30.2 1.8 3.1 3 0 0 3 3 3 2 EamA-like transporter family DUF914 PF06027.7 AEO56200.1 - 3.8e-06 26.0 10.0 3.8e-06 26.0 6.9 1.7 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) EmrE PF13536.1 AEO56200.1 - 1.3e-05 25.3 5.5 1.3e-05 25.3 3.8 3.6 3 1 0 3 3 3 1 Multidrug resistance efflux transporter UAA PF08449.6 AEO56200.1 - 5.5e-05 22.2 11.9 5.5e-05 22.2 8.3 1.4 2 0 0 2 2 2 1 UAA transporter family DUF3955 PF13127.1 AEO56200.1 - 6e-05 22.5 0.7 6e-05 22.5 0.5 3.2 4 1 1 5 5 5 1 Protein of unknown function (DUF3955) TPT PF03151.11 AEO56200.1 - 0.089 12.4 28.2 0.069 12.7 4.4 2.9 3 0 0 3 3 3 0 Triose-phosphate Transporter family Ras PF00071.17 AEO56201.1 - 5.3e-57 191.7 0.0 6.3e-57 191.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AEO56201.1 - 1.3e-18 67.6 0.0 1.9e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AEO56201.1 - 4e-13 48.9 0.0 4.7e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 AEO56201.1 - 1.6e-07 31.2 0.0 2.2e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 AEO56201.1 - 1.2e-06 27.8 0.0 1.5e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 AEO56201.1 - 3.2e-06 26.7 0.0 6.6e-05 22.4 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 AEO56201.1 - 0.00071 19.7 0.0 0.001 19.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 AEO56201.1 - 0.00099 18.3 0.1 0.0019 17.4 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_5 PF07728.9 AEO56201.1 - 0.0016 18.1 0.0 0.006 16.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) SRPRB PF09439.5 AEO56201.1 - 0.0021 17.3 0.0 0.0027 16.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 AEO56201.1 - 0.0044 17.0 0.0 0.01 15.8 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.1 AEO56201.1 - 0.0045 16.5 0.1 0.0077 15.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 AEO56201.1 - 0.0052 16.5 0.1 0.0096 15.6 0.0 1.5 2 0 0 2 2 2 1 Archaeal ATPase PduV-EutP PF10662.4 AEO56201.1 - 0.0067 15.9 0.0 0.1 12.1 0.0 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 AEO56201.1 - 0.0082 15.6 0.2 0.016 14.6 0.1 1.4 1 1 0 1 1 1 1 AAA-like domain ATP_bind_1 PF03029.12 AEO56201.1 - 0.0096 15.4 0.3 0.35 10.3 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Septin PF00735.13 AEO56201.1 - 0.013 14.4 0.0 0.032 13.2 0.0 1.7 2 0 0 2 2 2 0 Septin MobB PF03205.9 AEO56201.1 - 0.022 14.4 0.1 0.054 13.2 0.0 1.7 1 1 1 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 AEO56201.1 - 0.023 14.4 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 NTPase cobW PF02492.14 AEO56201.1 - 0.03 13.7 0.0 0.075 12.4 0.0 1.6 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 AEO56201.1 - 0.087 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain FeoB_N PF02421.13 AEO56201.1 - 0.088 12.0 0.0 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B GDA1_CD39 PF01150.12 AEO56203.1 - 1.5e-97 326.8 0.0 2.1e-97 326.3 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.11 AEO56203.1 - 0.13 11.4 0.0 0.32 10.1 0.0 1.7 1 0 0 1 1 1 0 Ppx/GppA phosphatase family Kinesin PF00225.18 AEO56204.1 - 6.8e-112 373.4 0.0 1.1e-111 372.7 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain PUL PF08324.6 AEO56204.1 - 2e-37 128.4 0.0 2.9e-37 127.9 0.0 1.2 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.9 AEO56204.1 - 4.7e-34 117.3 0.0 8.7e-34 116.4 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.15 AEO56204.1 - 2.3e-15 56.1 0.0 4.7e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 AEO56204.1 - 0.00026 21.1 0.1 0.0015 18.7 0.1 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.1 AEO56204.1 - 0.0017 18.1 0.0 0.0049 16.6 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin domain AhpC-TSA PF00578.16 AEO56204.1 - 0.0092 15.6 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family TraF PF13728.1 AEO56204.1 - 0.043 13.2 0.0 0.095 12.1 0.0 1.5 1 0 0 1 1 1 0 F plasmid transfer operon protein Phage_CP76 PF06892.6 AEO56204.1 - 0.093 12.0 0.5 17 4.7 0.0 2.3 2 0 0 2 2 2 0 Phage regulatory protein CII (CP76) Redoxin PF08534.5 AEO56204.1 - 0.13 11.8 0.1 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 Redoxin DUF87 PF01935.12 AEO56204.1 - 0.96 9.2 2.9 1.4 8.6 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 GAS PF13851.1 AEO56204.1 - 3.3 6.8 5.9 6.4 5.9 4.1 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Mnd1 PF03962.10 AEO56204.1 - 3.5 7.2 5.0 6.4 6.3 3.5 1.4 1 0 0 1 1 1 0 Mnd1 family DUF4598 PF15370.1 AEO56206.1 - 0.00011 22.4 3.8 0.00063 20.0 2.6 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4598) IF4E PF01652.13 AEO56207.1 - 2.7e-37 127.8 0.4 2.7e-37 127.8 0.3 1.4 2 0 0 2 2 2 1 Eukaryotic initiation factor 4E CMV_1a PF12467.3 AEO56207.1 - 0.0019 18.5 1.5 0.007 16.7 0.1 2.1 2 0 0 2 2 2 1 Cucumber mosaic virus 1a protein family DUF4557 PF15101.1 AEO56207.1 - 0.25 11.1 11.8 0.16 11.8 2.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Spt20 PF12090.3 AEO56207.1 - 0.66 9.3 8.4 1.6 8.0 1.0 2.3 2 0 0 2 2 2 0 Spt20 family ATAD4 PF15321.1 AEO56207.1 - 0.94 10.5 8.9 7.3 7.6 0.8 2.6 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 DUF1151 PF06625.6 AEO56207.1 - 4.3 7.0 12.7 0.42 10.3 3.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1151) EF-hand_9 PF14658.1 AEO56208.1 - 0.082 12.8 0.0 14 5.6 0.0 2.6 3 0 0 3 3 3 0 EF-hand domain Lactamase_B PF00753.22 AEO56209.1 - 2.7e-30 105.4 2.0 3.5e-30 105.1 1.4 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 AEO56209.1 - 4.3e-07 29.6 0.1 5.2e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF1236 PF06823.7 AEO56209.1 - 0.031 13.9 0.0 0.31 10.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1236) Las1 PF04031.8 AEO56210.1 - 2.2e-61 206.0 0.0 4.1e-61 205.1 0.0 1.5 1 0 0 1 1 1 1 Las1-like Mito_fiss_reg PF05308.6 AEO56210.1 - 0.018 14.4 4.0 0.032 13.6 2.8 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator Saccharop_dh PF03435.13 AEO56211.1 - 2.2e-133 444.9 0.0 2.6e-133 444.7 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 AEO56211.1 - 7.9e-06 26.0 0.1 1.4e-05 25.1 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 AEO56211.1 - 2.5e-05 24.3 0.5 4.2e-05 23.6 0.3 1.4 1 0 0 1 1 1 1 NADH(P)-binding IlvN PF07991.7 AEO56211.1 - 0.00037 19.9 0.5 0.012 14.9 0.0 2.7 3 0 0 3 3 3 1 Acetohydroxy acid isomeroreductase, catalytic domain GFO_IDH_MocA PF01408.17 AEO56211.1 - 0.11 13.0 0.5 0.25 11.8 0.1 1.8 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold TrkA_N PF02254.13 AEO56211.1 - 0.15 12.1 0.2 0.15 12.1 0.1 1.9 3 0 0 3 3 3 0 TrkA-N domain PfkB PF00294.19 AEO56213.1 - 5.4e-13 48.7 0.0 1.3e-11 44.2 0.0 2.1 1 1 0 1 1 1 1 pfkB family carbohydrate kinase NAD_kinase PF01513.16 AEO56214.1 - 5.2e-72 242.0 0.0 7.4e-72 241.5 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase TFIIF_alpha PF05793.7 AEO56214.1 - 0.053 11.8 6.6 0.091 11.1 4.6 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PAT1 PF09770.4 AEO56214.1 - 1.5 6.9 7.9 4.1 5.5 3.9 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Mito_fiss_reg PF05308.6 AEO56214.1 - 1.7 7.9 11.1 0.32 10.3 3.3 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator DnaJ PF00226.26 AEO56216.1 - 2.7e-27 94.3 1.6 4.2e-27 93.6 1.1 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 AEO56216.1 - 2.8e-21 75.2 3.5 3.7e-19 68.4 0.1 2.5 2 1 0 2 2 2 2 DnaJ C terminal domain GTP_EFTU PF00009.22 AEO56217.1 - 3.2e-60 202.7 0.1 4.2e-60 202.4 0.1 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 AEO56217.1 - 5.3e-25 87.4 0.0 1.1e-24 86.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 AEO56217.1 - 5.9e-16 58.3 3.7 5.9e-16 58.3 2.6 2.2 2 1 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 AEO56217.1 - 1.7e-05 24.7 0.0 3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 AEO56217.1 - 2.2e-05 23.9 1.0 6.9e-05 22.4 0.7 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 AEO56217.1 - 0.0018 18.7 0.0 0.0031 17.9 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 AEO56217.1 - 0.035 13.5 0.3 8.7 5.8 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.7 AEO56217.1 - 0.077 12.1 0.1 0.22 10.6 0.1 1.6 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Ribosomal_S14 PF00253.16 AEO56218.1 - 2.1e-20 71.8 4.1 2.3e-20 71.6 2.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Prim_Zn_Ribbon PF08273.7 AEO56218.1 - 0.02 14.9 0.9 2.2 8.4 0.1 2.1 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase DUF4428 PF14471.1 AEO56218.1 - 0.1 12.3 0.5 0.13 12.0 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) A2L_zn_ribbon PF08792.5 AEO56218.1 - 0.17 11.3 0.9 0.26 10.7 0.6 1.2 1 0 0 1 1 1 0 A2L zinc ribbon domain Thioredoxin PF00085.15 AEO56219.1 - 2e-64 213.7 0.0 3.4e-31 107.0 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 AEO56219.1 - 2.5e-24 85.7 2.8 3.1e-24 85.4 0.9 1.9 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 AEO56219.1 - 2.1e-22 79.4 0.1 1.2e-09 38.3 0.0 3.2 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 AEO56219.1 - 3.5e-15 55.7 0.7 1e-06 28.6 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_8 PF13905.1 AEO56219.1 - 5.9e-14 51.9 0.0 1.3e-05 25.2 0.0 2.9 2 1 1 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.16 AEO56219.1 - 1.5e-07 31.0 0.0 0.011 15.4 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.5 AEO56219.1 - 6.5e-07 29.0 0.2 0.03 13.8 0.0 2.6 2 0 0 2 2 2 2 Redoxin ERp29_N PF07912.8 AEO56219.1 - 2.1e-06 27.6 0.0 0.0029 17.5 0.0 2.7 2 0 0 2 2 2 2 ERp29, N-terminal domain Thioredoxin_6 PF13848.1 AEO56219.1 - 8.6e-06 25.6 0.5 0.014 15.1 0.0 3.1 3 1 1 4 4 4 3 Thioredoxin-like domain Thioredoxin_9 PF14595.1 AEO56219.1 - 0.0001 21.8 0.1 0.19 11.3 0.0 2.6 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_3 PF13192.1 AEO56219.1 - 0.00032 20.4 0.0 0.37 10.6 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin domain Thioredoxin_4 PF13462.1 AEO56219.1 - 0.001 19.0 1.2 1.3 9.0 0.0 3.4 3 2 1 4 4 4 1 Thioredoxin HyaE PF07449.6 AEO56219.1 - 0.0022 17.8 0.0 0.077 12.9 0.0 2.5 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Glutaredoxin PF00462.19 AEO56219.1 - 0.0026 17.7 0.1 3.8 7.5 0.0 2.9 2 1 0 2 2 2 2 Glutaredoxin DDE_Tnp_1_2 PF13586.1 AEO56219.1 - 0.015 15.5 0.0 3.6 7.8 0.0 2.5 2 0 0 2 2 2 0 Transposase DDE domain DUF3091 PF11291.3 AEO56219.1 - 0.081 12.8 0.1 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3091) Mu-like_Com PF10122.4 AEO56219.1 - 0.32 10.0 0.9 11 5.2 0.1 2.5 2 0 0 2 2 2 0 Mu-like prophage protein Com zf-rbx1 PF12678.2 AEO56220.1 - 5.2e-09 36.0 0.3 9.9e-09 35.1 0.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 AEO56220.1 - 3e-08 33.3 7.8 2.2e-07 30.6 5.4 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 AEO56220.1 - 2.1e-07 30.4 0.5 3.5e-07 29.7 0.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO56220.1 - 1.5e-05 24.6 3.8 3.4e-05 23.4 2.7 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 AEO56220.1 - 4.9e-05 23.2 2.2 4.9e-05 23.2 1.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AEO56220.1 - 7.4e-05 22.3 3.3 0.00022 20.8 2.3 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 AEO56220.1 - 0.0065 16.2 0.8 0.015 15.0 0.6 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2921 PF11145.3 AEO56220.1 - 0.052 11.2 0.1 0.073 10.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) RINGv PF12906.2 AEO56220.1 - 0.21 11.6 1.4 0.68 10.0 1.0 1.9 1 0 0 1 1 1 0 RING-variant domain DUF2463 PF09591.5 AEO56220.1 - 0.32 10.5 7.0 0.68 9.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2463) DUF1168 PF06658.7 AEO56220.1 - 0.84 9.1 3.1 0.51 9.8 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) zf-RING_UBOX PF13445.1 AEO56220.1 - 1.6 8.5 8.0 0.05 13.3 0.6 2.2 2 1 1 3 3 3 0 RING-type zinc-finger FANCL_C PF11793.3 AEO56220.1 - 2.3 8.2 5.3 7.7 6.5 3.6 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain HAD_2 PF13419.1 AEO56221.1 - 1.2e-16 61.3 0.0 1.9e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 AEO56221.1 - 6.3e-09 35.4 0.1 1.3e-08 34.4 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 AEO56221.1 - 1.6e-08 35.2 0.0 1.1e-07 32.5 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NIF PF03031.13 AEO56221.1 - 1.7e-06 27.8 0.0 0.00017 21.2 0.0 2.1 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Init_tRNA_PT PF04179.7 AEO56222.1 - 1.1e-147 492.5 0.0 1.5e-147 492.1 0.0 1.2 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Fungal_trans_2 PF11951.3 AEO56223.1 - 3.7e-07 29.0 0.1 6.1e-07 28.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO56223.1 - 6.9e-07 29.0 8.9 1.4e-06 28.1 6.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2823 PF11034.3 AEO56224.1 - 4.4e-29 100.4 15.6 4.9e-29 100.2 10.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2823) MT0933_antitox PF14013.1 AEO56224.1 - 0.1 12.7 7.6 2.9 8.0 0.0 2.2 1 1 1 2 2 2 0 MT0933-like antitoxin protein TipAS PF07739.8 AEO56224.1 - 0.31 11.3 3.6 0.33 11.2 2.5 1.1 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain RapA_C PF12137.3 AEO56224.1 - 0.39 9.5 3.0 0.41 9.4 2.1 1.0 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal DUF3402 PF11882.3 AEO56226.1 - 4.7e-156 519.9 0.0 6.8e-156 519.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 AEO56226.1 - 3.2e-74 249.4 0.0 5e-74 248.7 0.0 1.3 1 0 0 1 1 1 1 N1221-like protein CDK2AP PF09806.4 AEO56226.1 - 1.7 8.8 12.6 0.36 11.0 0.4 2.4 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein DUF2011 PF09428.5 AEO56227.1 - 1.8e-25 89.3 21.9 4e-25 88.2 15.2 1.6 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF2011) zf-HC2 PF13490.1 AEO56227.1 - 0.2 11.6 2.7 0.25 11.3 0.1 2.4 2 0 0 2 2 2 0 Putative zinc-finger RR_TM4-6 PF06459.7 AEO56227.1 - 1.6 8.5 11.1 0.29 10.9 2.0 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Neur_chan_memb PF02932.11 AEO56227.1 - 2.5 7.9 7.8 4.9 6.9 5.4 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Radial_spoke_3 PF06098.6 AEO56227.1 - 7.7 5.4 17.5 15 4.5 12.1 1.4 1 0 0 1 1 1 0 Radial spoke protein 3 NDT80_PhoG PF05224.7 AEO56228.1 - 5.8e-39 134.0 0.2 2.1e-38 132.1 0.0 1.9 2 0 0 2 2 2 1 NDT80 / PhoG like DNA-binding family SelP_N PF04592.9 AEO56228.1 - 1.5 8.1 9.3 3.1 7.1 6.5 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region RWD PF05773.17 AEO56230.1 - 7.7e-20 70.8 0.0 1.2e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 RWD domain IBR PF01485.16 AEO56230.1 - 1.4e-19 69.7 30.2 6.3e-13 48.4 2.7 3.6 3 1 1 4 4 4 2 IBR domain zf-RING_5 PF14634.1 AEO56230.1 - 0.00025 20.6 3.2 0.00025 20.6 2.2 3.7 3 1 0 3 3 3 2 zinc-RING finger domain zf-RING_2 PF13639.1 AEO56230.1 - 0.0015 18.3 8.1 0.0015 18.3 5.6 3.8 3 2 0 3 3 3 2 Ring finger domain zf-RING_UBOX PF13445.1 AEO56230.1 - 0.0028 17.3 2.2 0.0028 17.3 1.5 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 AEO56230.1 - 0.01 15.8 8.1 0.01 15.8 5.6 4.3 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AEO56230.1 - 0.014 15.0 6.5 0.014 15.0 4.5 4.6 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) C1_4 PF07975.7 AEO56230.1 - 0.045 13.7 0.7 0.045 13.7 0.5 3.6 3 0 0 3 3 3 0 TFIIH C1-like domain zf-rbx1 PF12678.2 AEO56230.1 - 1.3 9.2 18.1 0.47 10.5 0.2 3.5 3 0 0 3 3 3 0 RING-H2 zinc finger FYVE PF01363.16 AEO56230.1 - 9.6 6.1 25.3 2.5 8.0 4.2 3.4 3 0 0 3 3 3 0 FYVE zinc finger PAP2 PF01569.16 AEO56231.1 - 1.5e-18 66.6 0.4 4.3e-18 65.2 0.3 1.7 1 1 0 1 1 1 1 PAP2 superfamily BPD_transp_2 PF02653.11 AEO56231.1 - 0.0051 15.8 3.3 0.47 9.3 0.5 2.1 2 0 0 2 2 2 2 Branched-chain amino acid transport system / permease component MARVEL PF01284.18 AEO56232.1 - 1.1e-06 28.5 11.8 1.5e-06 28.0 8.2 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF1469 PF07332.6 AEO56232.1 - 6.3 6.5 14.2 22 4.7 7.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) DUF4233 PF14017.1 AEO56232.1 - 8.5 6.3 10.5 1.8 8.5 3.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4233) WSC PF01822.14 AEO56233.1 - 1.9e-75 248.7 69.6 3.7e-20 71.6 5.9 5.2 5 0 0 5 5 5 4 WSC domain peroxidase PF00141.18 AEO56233.1 - 7.6e-24 84.4 0.0 2e-23 83.0 0.0 1.7 1 0 0 1 1 1 1 Peroxidase Fungal_trans PF04082.13 AEO56235.1 - 5.3e-33 113.9 0.0 8.2e-33 113.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO56235.1 - 6e-07 29.2 9.2 1.1e-06 28.4 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GAS2 PF02187.12 AEO56236.1 - 5.3e-05 22.9 0.1 0.0001 21.9 0.0 1.3 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Lipase_3 PF01764.20 AEO56237.1 - 1.7e-39 134.6 0.0 2.4e-39 134.1 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_8 PF06259.7 AEO56237.1 - 0.00027 20.4 0.1 0.00047 19.6 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase DUF676 PF05057.9 AEO56237.1 - 0.00096 18.4 0.0 0.0014 17.9 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Esterase PF00756.15 AEO56237.1 - 0.0018 17.7 0.0 0.0031 16.9 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 AEO56237.1 - 0.0018 18.0 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 AEO56237.1 - 0.0023 17.5 0.0 0.004 16.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 AEO56237.1 - 0.0063 16.7 0.0 0.01 16.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain DUF2974 PF11187.3 AEO56237.1 - 0.008 15.5 0.7 0.087 12.1 0.5 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.2 AEO56237.1 - 0.0081 16.0 0.1 0.012 15.5 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 AEO56237.1 - 0.01 15.4 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DLH PF01738.13 AEO56237.1 - 0.059 12.6 0.1 0.098 11.9 0.1 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Cutinase PF01083.17 AEO56237.1 - 0.11 12.2 0.7 0.25 11.0 0.5 1.7 1 1 0 1 1 1 0 Cutinase Glyco_hydro_3 PF00933.16 AEO56238.1 - 2e-89 299.5 0.0 2.8e-89 299.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 AEO56238.1 - 3.1e-55 187.1 0.0 4.9e-54 183.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 AEO56238.1 - 9.8e-23 79.8 0.0 1.8e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Ribosomal_L34 PF00468.12 AEO56240.1 - 5.8e-13 48.2 12.0 1e-12 47.5 8.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L34 Peptidase_M48 PF01435.13 AEO56241.1 - 1.6e-50 171.7 0.0 2.3e-50 171.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 AEO56241.1 - 0.0011 18.0 0.1 0.002 17.1 0.1 1.5 1 0 0 1 1 1 1 BlaR1 peptidase M56 DUF955 PF06114.8 AEO56241.1 - 0.17 11.6 0.5 0.95 9.1 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF955) DUF4538 PF15061.1 AEO56241.1 - 0.19 11.0 0.7 0.5 9.7 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) Ish1 PF10281.4 AEO56242.1 - 2.9e-05 24.0 0.3 6.3e-05 22.9 0.2 1.5 1 1 0 1 1 1 1 Putative stress-responsive nuclear envelope protein SAP PF02037.22 AEO56242.1 - 0.00047 19.5 0.0 0.00067 19.0 0.0 1.3 1 1 0 1 1 1 1 SAP domain HTH_29 PF13551.1 AEO56242.1 - 0.068 13.3 0.4 0.089 12.9 0.2 1.3 1 1 0 1 1 1 0 Winged helix-turn helix DUF4129 PF13559.1 AEO56242.1 - 0.083 12.8 0.4 0.099 12.6 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) HTH_32 PF13565.1 AEO56242.1 - 0.5 11.2 2.6 0.63 10.8 1.5 1.6 1 1 1 2 2 2 0 Homeodomain-like domain Ribosomal_L38e PF01781.13 AEO56243.1 - 5.4e-34 115.7 2.9 6.1e-34 115.5 2.0 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family CLTH PF10607.4 AEO56243.1 - 0.058 13.0 0.1 0.062 12.9 0.1 1.1 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain GHMP_kinases_N PF00288.21 AEO56245.1 - 9e-19 67.3 0.0 2.1e-18 66.1 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 AEO56245.1 - 8.8e-11 41.8 0.0 2.2e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 AEO56245.1 - 0.0094 15.2 0.0 0.019 14.1 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature PPTA PF01239.17 AEO56246.1 - 2.4e-39 131.0 12.0 1e-06 27.8 0.2 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_8 PF13181.1 AEO56246.1 - 0.006 16.2 2.1 0.1 12.4 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat PGA2 PF07543.7 AEO56248.1 - 4.7e-43 146.3 2.6 5.4e-43 146.1 1.8 1.0 1 0 0 1 1 1 1 Protein trafficking PGA2 CENP-S PF15630.1 AEO56249.1 - 6.5e-36 122.3 0.1 8.2e-36 122.0 0.0 1.1 1 0 0 1 1 1 1 Kinetochore component CENP-S Bromo_TP PF07524.8 AEO56249.1 - 0.00024 20.7 0.0 0.00037 20.1 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated CENP-T PF15511.1 AEO56249.1 - 0.00089 18.6 0.0 0.0012 18.1 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T TFIID-18kDa PF02269.11 AEO56249.1 - 0.007 16.1 0.1 0.008 15.9 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit TAF PF02969.12 AEO56249.1 - 0.029 14.3 0.2 0.21 11.5 0.0 2.1 1 1 1 2 2 2 0 TATA box binding protein associated factor (TAF) TFIID-31kDa PF02291.10 AEO56249.1 - 0.032 14.0 0.2 0.042 13.6 0.2 1.3 1 1 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit PCP_red PF08369.5 AEO56249.1 - 0.038 13.8 0.0 0.095 12.5 0.0 1.7 1 0 0 1 1 1 0 Proto-chlorophyllide reductase 57 kD subunit Histone PF00125.19 AEO56249.1 - 0.051 13.7 0.0 0.063 13.4 0.0 1.2 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Rubella_E2 PF05749.6 AEO56250.1 - 0.018 14.3 1.2 0.036 13.3 0.9 1.5 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 Dicty_REP PF05086.7 AEO56250.1 - 2.6 5.6 9.1 3.5 5.2 6.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein WD40 PF00400.27 AEO56251.1 - 7.3e-68 222.2 12.1 3.5e-09 36.1 0.0 11.8 11 1 0 11 11 11 10 WD domain, G-beta repeat Utp13 PF08625.6 AEO56251.1 - 3e-45 153.3 0.1 5e-45 152.6 0.1 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 AEO56251.1 - 4.8e-07 28.3 0.7 0.0037 15.4 0.0 4.4 4 2 1 5 5 5 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 AEO56251.1 - 2e-05 23.5 7.0 1.7 7.3 0.0 5.2 6 1 0 6 6 6 4 Nup133 N terminal like UCH PF00443.24 AEO56252.1 - 2.2e-24 86.0 0.0 3.3e-24 85.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 AEO56252.1 - 5.4e-12 45.6 0.3 9.4e-12 44.8 0.2 1.3 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein Inhibitor_I53 PF11714.3 AEO56252.1 - 0.2 11.6 2.1 0.55 10.2 1.5 1.7 1 0 0 1 1 1 0 Thrombin inhibitor Madanin IF4E PF01652.13 AEO56253.1 - 7e-51 172.0 0.0 7e-51 172.0 0.0 1.6 2 0 0 2 2 2 1 Eukaryotic initiation factor 4E DUF4557 PF15101.1 AEO56253.1 - 1.9 8.2 13.6 2.7 7.7 9.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) SelP_N PF04592.9 AEO56253.1 - 6.9 5.9 18.1 9.7 5.4 12.6 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region LIM_bind PF01803.11 AEO56253.1 - 9.8 5.2 13.5 15 4.6 9.4 1.2 1 0 0 1 1 1 0 LIM-domain binding protein MTHFR PF02219.12 AEO56254.1 - 1.3e-100 336.1 0.0 1.8e-100 335.7 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase PQ-loop PF04193.9 AEO56256.1 - 1.7e-16 59.4 8.1 1.1e-12 47.3 1.0 3.0 3 0 0 3 3 3 2 PQ loop repeat Zn_clus PF00172.13 AEO56258.1 - 1.4e-07 31.2 8.3 2.4e-07 30.5 5.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 AEO56259.1 - 1.4e-23 81.8 18.4 2.7e-06 27.0 0.6 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat PQQ PF01011.16 AEO56259.1 - 0.0027 17.1 3.5 2.6 7.7 0.2 4.0 4 0 0 4 4 4 2 PQQ enzyme repeat PQQ_3 PF13570.1 AEO56259.1 - 0.049 13.9 16.5 2.4 8.5 1.4 5.1 4 1 1 5 5 5 0 PQQ-like domain Glyco_transf_15 PF01793.11 AEO56260.1 - 1.2e-138 461.5 10.0 1.5e-138 461.3 7.0 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Herpes_LAMP2 PF06126.6 AEO56260.1 - 0.27 9.5 0.1 0.41 8.9 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 Spc97_Spc98 PF04130.8 AEO56261.1 - 3.5e-69 233.5 0.0 4.4e-69 233.2 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family GCP5-Mod21 PF14609.1 AEO56261.1 - 0.15 10.1 0.0 0.22 9.5 0.0 1.3 1 1 0 1 1 1 0 gamma-Tubulin ring complex non-core subunit mod21 Pkinase PF00069.20 AEO56262.1 - 3e-13 49.5 0.0 4.2e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO56262.1 - 7.5e-13 48.1 0.0 8.3e-12 44.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 AEO56262.1 - 0.00013 21.0 0.0 0.0002 20.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 AEO56262.1 - 0.0004 19.4 0.0 0.00095 18.2 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 AEO56262.1 - 0.00043 20.0 0.0 0.00076 19.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 AEO56262.1 - 0.022 14.3 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.20 AEO56263.1 - 2.1e-18 66.4 0.0 2.7e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO56263.1 - 1.3e-08 34.2 0.0 1.7e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO56263.1 - 2.2e-06 26.8 0.0 2.9e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 AEO56263.1 - 0.00019 20.5 0.1 0.00028 20.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 AEO56263.1 - 0.0011 18.3 0.0 0.0016 17.7 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 AEO56263.1 - 0.0058 16.3 0.2 0.019 14.6 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 AEO56263.1 - 0.017 13.9 0.0 0.031 13.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DUF572 PF04502.8 AEO56264.1 - 3.4e-77 259.8 1.9 3.9e-77 259.6 1.3 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Gin PF10764.4 AEO56264.1 - 0.088 12.5 0.1 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Inhibitor of sigma-G Gin Serglycin PF04360.7 AEO56264.1 - 0.13 12.0 0.4 0.22 11.2 0.3 1.4 1 0 0 1 1 1 0 Serglycin DUF3246 PF11596.3 AEO56264.1 - 0.72 9.0 5.7 1 8.5 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Sugarporin_N PF11471.3 AEO56264.1 - 2.1 8.0 10.4 14 5.4 7.2 2.4 1 1 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Glyco_hydro_18 PF00704.23 AEO56266.1 - 1.2e-08 34.8 0.0 3e-08 33.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 DUF1996 PF09362.5 AEO56267.1 - 5.7e-77 258.5 0.0 7.4e-77 258.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) TPR_11 PF13414.1 AEO56268.1 - 3e-09 36.3 0.6 1.4e-08 34.2 0.0 2.3 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 AEO56268.1 - 5.9e-05 22.6 3.2 0.65 10.0 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 AEO56268.1 - 8e-05 22.0 0.2 0.1 12.2 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat UBA PF00627.26 AEO56268.1 - 8.8e-05 22.2 0.0 0.0003 20.5 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain DnaJ PF00226.26 AEO56268.1 - 0.0021 17.7 0.0 0.0052 16.4 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain TPR_12 PF13424.1 AEO56268.1 - 0.056 13.3 0.1 0.056 13.3 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF630 PF04783.7 AEO56268.1 - 0.078 12.8 0.5 0.2 11.5 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF630) UQ_con PF00179.21 AEO56269.1 - 8.3e-52 174.3 0.0 9.3e-52 174.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme MutS_III PF05192.13 AEO56270.1 - 0.017 14.9 0.1 4.8 6.8 0.1 2.4 2 0 0 2 2 2 0 MutS domain III LSM PF01423.17 AEO56271.1 - 4.7e-15 54.8 0.3 6.5e-15 54.4 0.2 1.2 1 0 0 1 1 1 1 LSM domain Peptidase_M18 PF02127.10 AEO56274.1 - 1.3e-123 412.7 0.0 1.4e-123 412.5 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) TMEM125 PF15109.1 AEO56274.1 - 0.064 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 TMEM125 protein family SPX PF03105.14 AEO56275.1 - 5.8e-60 203.4 0.1 5.8e-60 203.4 0.1 2.2 2 0 0 2 2 2 1 SPX domain EXS PF03124.9 AEO56275.1 - 2.7e-49 168.0 21.0 4.1e-27 95.1 4.0 2.1 1 1 1 2 2 2 2 EXS family Ninjurin PF04923.7 AEO56275.1 - 0.11 12.1 0.0 2.1 8.1 0.0 2.3 2 0 0 2 2 2 0 Ninjurin CagE_TrbE_VirB PF03135.9 AEO56275.1 - 0.2 11.3 0.5 0.38 10.4 0.3 1.4 1 0 0 1 1 1 0 CagE, TrbE, VirB family, component of type IV transporter system Zip PF02535.17 AEO56275.1 - 9.8 5.0 9.2 27 3.6 6.4 1.7 1 0 0 1 1 1 0 ZIP Zinc transporter CAF1A PF12253.3 AEO56277.1 - 5.2e-23 80.9 2.3 5.2e-23 80.9 1.6 2.7 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.3 AEO56277.1 - 7.8e-09 35.2 37.4 1.8e-08 34.0 26.0 1.6 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DDRGK PF09756.4 AEO56277.1 - 2.1 7.7 36.7 4.4 6.6 25.4 1.6 1 0 0 1 1 1 0 DDRGK domain Borrelia_P83 PF05262.6 AEO56277.1 - 2.7 6.1 23.6 3.9 5.6 16.4 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein Peptidase_S64 PF08192.6 AEO56277.1 - 10 4.3 9.5 14 3.8 6.6 1.2 1 0 0 1 1 1 0 Peptidase family S64 Peptidase_M50B PF13398.1 AEO56278.1 - 1.2e-49 168.4 16.7 1.8e-49 167.8 11.5 1.2 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M50 PF02163.17 AEO56278.1 - 1 8.2 10.2 0.069 12.0 3.0 2.1 2 1 0 2 2 2 0 Peptidase family M50 O-antigen_lig PF13425.1 AEO56278.1 - 9.8 6.1 15.5 2.3 8.2 6.1 2.4 2 1 0 2 2 2 0 O-antigen ligase like membrane protein Glyoxalase PF00903.20 AEO56279.1 - 1.9e-09 37.5 0.3 3e-09 36.9 0.2 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 AEO56279.1 - 2.1e-08 34.7 0.3 2.7e-08 34.3 0.2 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain FLILHELTA PF10306.4 AEO56280.1 - 9.9e-29 99.2 0.0 1.6e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA Mucin PF01456.12 AEO56280.1 - 0.00076 19.2 25.5 0.0014 18.3 17.7 1.5 1 0 0 1 1 1 1 Mucin-like glycoprotein TMEM154 PF15102.1 AEO56280.1 - 0.22 11.2 2.4 0.32 10.7 1.7 1.3 1 0 0 1 1 1 0 TMEM154 protein family SSP160 PF06933.6 AEO56280.1 - 4.5 5.1 20.4 6.2 4.6 14.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF1115 PF06544.7 AEO56281.1 - 0.0027 17.3 0.1 0.0095 15.6 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1115) DUF3786 PF12654.2 AEO56283.1 - 0.089 12.0 0.1 0.1 11.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3786) RVT_1 PF00078.22 AEO56283.1 - 0.13 11.5 0.3 0.14 11.4 0.2 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DNA_ligase_A_M PF01068.16 AEO56284.1 - 1.5e-22 79.9 0.0 2.9e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 AEO56284.1 - 8.7e-17 61.4 0.0 1.6e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus Transp_cyt_pur PF02133.10 AEO56285.1 - 4.9e-36 124.2 34.5 2e-35 122.2 22.7 2.1 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MerT PF02411.10 AEO56285.1 - 2.6 7.8 12.6 0.22 11.3 2.4 3.2 2 2 1 3 3 3 0 MerT mercuric transport protein TAFII55_N PF04658.8 AEO56286.1 - 0.0031 17.0 2.8 0.032 13.7 0.1 2.1 1 1 1 2 2 2 2 TAFII55 protein conserved region Dicty_REP PF05086.7 AEO56287.1 - 0.083 10.6 1.6 0.095 10.4 1.1 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Sec39 PF08314.6 AEO56288.1 - 4.8e-230 765.2 0.0 5.5e-230 765.0 0.0 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 RAP1 PF07218.6 AEO56288.1 - 0.23 9.5 0.6 0.32 9.0 0.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DIOX_N PF14226.1 AEO56290.1 - 1.5e-23 83.4 0.0 2.2e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 AEO56290.1 - 1.7e-12 47.4 0.0 3.8e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GCD14 PF08704.5 AEO56291.1 - 1.1e-64 218.2 0.0 2.2e-48 164.9 0.0 2.6 2 1 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 AEO56291.1 - 1.6e-05 24.8 0.1 5.2e-05 23.2 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO56291.1 - 0.0011 19.5 0.0 0.0029 18.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain K_channel_TID PF07941.6 AEO56291.1 - 5.9 7.1 16.5 0.04 14.1 3.1 3.5 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain MS_channel PF00924.13 AEO56293.1 - 2.1e-21 76.2 2.8 5.9e-21 74.7 2.1 1.6 2 0 0 2 2 2 1 Mechanosensitive ion channel EF-hand_7 PF13499.1 AEO56293.1 - 0.024 14.7 0.1 0.073 13.2 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.27 AEO56293.1 - 0.035 13.3 0.5 0.089 12.1 0.3 1.7 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.1 AEO56293.1 - 0.16 11.9 0.0 0.72 9.8 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain DUF3671 PF12420.3 AEO56293.1 - 0.2 11.6 4.9 0.22 11.5 0.4 2.6 2 1 0 2 2 2 0 Protein of unknown function HemY_N PF07219.8 AEO56293.1 - 0.83 9.2 7.4 0.19 11.3 0.4 2.7 2 0 0 2 2 2 0 HemY protein N-terminus NDK PF00334.14 AEO56294.1 - 5.1e-55 184.9 0.0 5.8e-55 184.7 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Glyco_hydro_31 PF01055.21 AEO56295.1 - 1.5e-155 518.3 3.0 2e-155 517.9 2.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 AEO56295.1 - 7.5e-24 83.3 0.3 3e-23 81.4 0.1 2.1 2 0 0 2 2 2 1 Galactose mutarotase-like Peptidase_A4 PF01828.12 AEO56296.1 - 9e-23 80.4 0.0 3.5e-22 78.5 0.0 1.7 1 1 0 1 1 1 1 Peptidase A4 family Ndufs5 PF10200.4 AEO56297.1 - 0.00031 20.6 0.0 0.0004 20.3 0.0 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.3 AEO56297.1 - 0.039 14.0 0.8 0.074 13.1 0.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) COX6B PF02297.12 AEO56297.1 - 0.04 13.9 0.1 0.066 13.2 0.1 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb CHCH PF06747.8 AEO56297.1 - 0.055 13.4 0.2 0.12 12.3 0.1 1.6 1 1 0 1 1 1 0 CHCH domain FAD_binding_6 PF00970.19 AEO56299.1 - 0.00057 19.9 0.0 0.001 19.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 AEO56299.1 - 0.00064 20.2 0.1 1.7 9.2 0.0 2.3 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 AEO56299.1 - 0.13 12.1 0.1 5.4 6.8 0.0 2.2 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Peptidase_C48 PF02902.14 AEO56300.1 - 3.4e-30 105.2 0.0 5.4e-30 104.6 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain WD40 PF00400.27 AEO56301.1 - 1.2e-27 94.7 5.3 2e-07 30.6 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 AEO56301.1 - 0.0021 16.2 0.2 0.55 8.3 0.0 2.4 2 0 0 2 2 2 2 Nucleoporin Nup120/160 ParBc PF02195.13 AEO56301.1 - 0.055 13.5 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 ParB-like nuclease domain gpW PF02831.10 AEO56301.1 - 0.071 12.6 0.2 0.17 11.4 0.1 1.6 1 0 0 1 1 1 0 gpW Proteasome PF00227.21 AEO56302.1 - 9.1e-38 129.4 0.0 1.1e-37 129.2 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DEAD PF00270.24 AEO56303.1 - 6.5e-47 159.1 0.0 2.7e-45 153.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO56303.1 - 2.1e-29 101.2 0.0 4e-29 100.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 AEO56303.1 - 0.0028 16.4 0.0 0.0037 16.0 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 AEO56303.1 - 0.0083 15.9 0.0 0.019 14.8 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 AEO56303.1 - 0.046 12.1 0.0 0.12 10.7 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1253) CMS1 PF14617.1 AEO56303.1 - 0.15 11.1 0.1 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ORC2 PF04084.9 AEO56304.1 - 2.4e-94 315.8 0.0 2.9e-94 315.5 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 NTP_transf_3 PF12804.2 AEO56304.1 - 8.7e-05 22.6 1.0 0.00019 21.5 0.7 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain PGP_phosphatase PF09419.5 AEO56305.1 - 7.8e-67 223.8 0.0 9.1e-67 223.6 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 AEO56305.1 - 7.3e-05 22.3 0.1 0.00021 20.9 0.0 1.7 1 1 0 1 1 1 1 HAD-hyrolase-like Vpu PF00558.14 AEO56306.1 - 0.18 11.3 0.4 0.4 10.2 0.1 1.6 2 0 0 2 2 2 0 Vpu protein CutC PF03932.9 AEO56308.1 - 1.8e-13 50.1 0.0 6e-09 35.4 0.0 2.4 2 1 0 2 2 2 2 CutC family Alk_phosphatase PF00245.15 AEO56309.1 - 7.6e-63 212.6 0.0 2.7e-62 210.8 0.0 1.7 1 1 0 1 1 1 1 Alkaline phosphatase Phosphodiest PF01663.17 AEO56309.1 - 2.2e-07 30.5 1.1 2.4e-06 27.1 0.1 2.2 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 AEO56309.1 - 2.5e-05 23.6 0.0 4.9e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.12 AEO56309.1 - 0.011 14.1 0.2 0.016 13.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) FTA4 PF13093.1 AEO56309.1 - 0.15 11.4 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 TPR_2 PF07719.12 AEO56310.1 - 7.5e-24 81.6 34.0 0.0016 18.2 0.7 10.8 11 0 0 11 11 10 7 Tetratricopeptide repeat Apc3 PF12895.2 AEO56310.1 - 1.2e-23 83.0 21.6 5.9e-20 71.1 0.5 6.1 4 2 4 8 8 8 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 AEO56310.1 - 3.1e-21 75.4 28.5 6.2e-06 26.4 0.0 9.2 5 3 3 10 10 10 7 Tetratricopeptide repeat TPR_11 PF13414.1 AEO56310.1 - 1.4e-20 72.7 32.1 4.4e-06 26.2 0.4 8.0 4 3 3 8 8 8 7 TPR repeat TPR_1 PF00515.23 AEO56310.1 - 9.2e-19 66.1 23.9 0.00035 20.0 0.9 10.2 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_12 PF13424.1 AEO56310.1 - 3.6e-17 62.0 36.4 6.9e-08 32.3 1.2 8.8 6 4 1 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 AEO56310.1 - 3.3e-15 55.1 44.4 0.0073 16.8 0.1 11.2 5 2 6 11 11 10 4 Tetratricopeptide repeat TPR_16 PF13432.1 AEO56310.1 - 4.2e-14 52.7 42.4 8.4e-06 26.3 1.8 8.6 7 1 3 10 10 9 5 Tetratricopeptide repeat TPR_8 PF13181.1 AEO56310.1 - 1.6e-12 46.1 2.3 0.0061 16.2 0.4 7.9 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_15 PF13429.1 AEO56310.1 - 6.3e-06 25.4 10.7 0.011 14.7 0.3 5.1 3 2 1 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 AEO56310.1 - 0.00031 20.6 11.1 21 5.6 0.0 8.3 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_7 PF13176.1 AEO56310.1 - 0.00059 19.4 26.6 6 6.9 0.1 9.0 11 0 0 11 11 10 1 Tetratricopeptide repeat TPR_10 PF13374.1 AEO56310.1 - 0.0012 18.6 28.2 0.11 12.4 0.1 7.8 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_6 PF13174.1 AEO56310.1 - 0.021 15.2 21.9 0.91 10.1 0.4 8.4 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_5 PF12688.2 AEO56310.1 - 0.022 14.7 0.8 0.085 12.8 0.2 2.3 2 0 0 2 2 2 0 Tetratrico peptide repeat Cohesin_load PF10345.4 AEO56310.1 - 0.19 9.8 0.4 8.2 4.5 0.0 2.7 2 1 0 2 2 2 0 Cohesin loading factor PTS_IIA PF02255.11 AEO56310.1 - 0.24 11.2 1.2 0.78 9.6 0.1 2.4 3 0 0 3 3 3 0 PTS system, Lactose/Cellobiose specific IIA subunit Coatomer_E PF04733.9 AEO56310.1 - 1.3 8.1 4.0 13 4.8 0.1 3.7 5 0 0 5 5 5 0 Coatomer epsilon subunit DUF3245 PF11595.3 AEO56310.1 - 1.7 8.8 4.6 7.7 6.7 0.8 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3245) AMP-binding PF00501.23 AEO56311.1 - 4.7e-52 176.7 0.0 7.2e-52 176.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 AEO56311.1 - 0.0046 17.8 0.0 0.0097 16.8 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FAT PF02259.18 AEO56312.1 - 3.7e-76 256.3 7.2 4.8e-76 256.0 4.0 1.9 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 AEO56312.1 - 1.6e-24 86.7 0.3 7.3e-24 84.5 0.1 2.3 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 AEO56312.1 - 8.3e-10 37.9 0.1 2.3e-09 36.5 0.1 1.8 1 0 0 1 1 1 1 FATC domain Urb2 PF10441.4 AEO56312.1 - 0.0018 17.9 0.7 1 8.9 0.0 4.0 5 0 0 5 5 5 1 Urb2/Npa2 family Glycolytic PF00274.14 AEO56312.1 - 0.14 10.5 0.0 0.24 9.7 0.0 1.2 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-I Chitin_bind_3 PF03067.10 AEO56313.1 - 0.00029 21.1 0.1 0.00052 20.3 0.1 1.4 1 1 0 1 1 1 1 Chitin binding domain Glyco_hydro_61 PF03443.9 AEO56313.1 - 0.0038 17.0 0.0 0.0074 16.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 tRNA_SAD PF07973.9 AEO56314.1 - 9.2e-07 28.6 0.6 1.7e-06 27.7 0.5 1.4 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.14 AEO56314.1 - 1.8e-06 26.5 0.0 3.1e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) AIG2 PF06094.7 AEO56315.1 - 1.6e-19 70.2 0.3 2.3e-19 69.7 0.2 1.2 1 0 0 1 1 1 1 AIG2-like family UPF0029 PF01205.14 AEO56316.1 - 7.1e-31 106.1 0.0 1e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 AEO56316.1 - 2.9e-07 30.3 0.0 6.5e-07 29.2 0.0 1.6 1 1 0 1 1 1 1 RWD domain UQ_con PF00179.21 AEO56316.1 - 0.05 13.0 0.0 0.2 11.1 0.0 1.9 1 1 1 2 2 2 0 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AEO56316.1 - 0.11 12.2 0.1 0.24 11.1 0.1 1.6 1 1 0 1 1 1 0 Prokaryotic E2 family B ACT_7 PF13840.1 AEO56317.1 - 9.7e-21 73.0 1.8 6.9e-18 63.9 0.0 3.0 3 0 0 3 3 3 2 ACT domain Methyltransf_32 PF13679.1 AEO56318.1 - 1.5e-19 70.0 0.0 7.1e-19 67.8 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Ribosomal_S13 PF00416.17 AEO56319.1 - 3.9e-22 78.7 0.1 4.4e-22 78.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 Peptidase_M19 PF01244.16 AEO56320.1 - 1.3e-96 323.3 0.0 1.5e-96 323.1 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) FCH PF00611.18 AEO56321.1 - 3.6e-17 62.3 0.3 5.7e-16 58.4 0.0 2.9 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain RhoGAP PF00620.22 AEO56321.1 - 4.5e-15 55.5 0.1 1.9e-14 53.5 0.0 2.2 2 0 0 2 2 2 1 RhoGAP domain DEP PF00610.16 AEO56321.1 - 4e-14 52.1 0.0 8.4e-14 51.0 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) KIP1 PF07765.7 AEO56321.1 - 0.088 12.6 0.0 2.3 8.1 0.0 2.7 2 0 0 2 2 2 0 KIP1-like protein IncA PF04156.9 AEO56321.1 - 1 8.9 4.5 0.62 9.6 0.8 2.4 2 0 0 2 2 2 0 IncA protein TMF_DNA_bd PF12329.3 AEO56321.1 - 5.5 6.8 8.1 0.45 10.3 1.6 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding RVT_1 PF00078.22 AEO56322.1 - 1.8e-08 34.0 0.0 1.5e-06 27.7 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4407 PF14362.1 AEO56322.1 - 0.0025 16.8 0.0 0.0025 16.8 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4407) Flavin_Reduct PF01613.13 AEO56323.1 - 1e-15 57.8 0.1 1.7e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Flavin reductase like domain DUF1509 PF07420.6 AEO56323.1 - 0.53 9.5 4.9 0.72 9.0 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) MARVEL PF01284.18 AEO56324.1 - 6.9e-06 25.9 12.4 1.1e-05 25.3 8.6 1.3 1 0 0 1 1 1 1 Membrane-associating domain TRAM_LAG1_CLN8 PF03798.11 AEO56324.1 - 0.0081 15.7 5.2 0.013 15.0 3.6 1.2 1 0 0 1 1 1 1 TLC domain DUF4281 PF14108.1 AEO56324.1 - 0.0091 16.0 4.1 0.02 15.0 2.8 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4281) Nop16 PF09420.5 AEO56325.1 - 3.9e-53 179.9 7.4 2.8e-52 177.1 5.1 1.8 1 1 0 1 1 1 1 Ribosome biogenesis protein Nop16 Fungal_trans_2 PF11951.3 AEO56326.1 - 5.3e-47 160.2 0.0 5.2e-29 101.0 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO56326.1 - 5.7e-07 29.3 7.0 1.2e-06 28.3 4.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GSHPx PF00255.14 AEO56327.1 - 2.3e-42 142.7 0.0 2.9e-42 142.4 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 AEO56327.1 - 3.1e-05 23.6 0.1 5.3e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family DUF4174 PF13778.1 AEO56327.1 - 0.00024 21.1 0.0 0.00038 20.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4174) Redoxin PF08534.5 AEO56327.1 - 0.0019 17.7 0.0 0.0031 17.0 0.0 1.4 2 0 0 2 2 2 1 Redoxin DAO PF01266.19 AEO56328.1 - 1.9e-56 191.5 2.5 4.8e-56 190.1 1.7 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 AEO56328.1 - 1.6e-06 28.3 0.1 0.014 15.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AEO56328.1 - 6e-05 22.9 0.4 0.00014 21.7 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 AEO56328.1 - 0.00074 18.2 1.4 0.0022 16.7 0.2 1.9 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 AEO56328.1 - 0.0012 18.7 0.4 1.5 8.6 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 AEO56328.1 - 0.0069 15.2 1.9 0.46 9.2 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Mqo PF06039.10 AEO56328.1 - 0.019 13.1 0.0 0.51 8.4 0.0 2.0 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Thi4 PF01946.12 AEO56328.1 - 0.036 13.1 0.1 0.068 12.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family GMC_oxred_N PF00732.14 AEO56328.1 - 0.046 12.8 0.2 5.8 5.9 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase Strep_67kDa_ant PF06100.6 AEO56328.1 - 0.26 9.6 0.3 0.43 8.8 0.0 1.4 2 0 0 2 2 2 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family DHDPS PF00701.17 AEO56329.1 - 1e-33 116.2 0.0 1.2e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family GFO_IDH_MocA PF01408.17 AEO56330.1 - 3.2e-10 40.5 0.9 1.4e-09 38.5 0.6 2.1 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 AEO56330.1 - 0.03 14.7 0.1 0.084 13.2 0.0 1.8 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain CoA_binding_2 PF13380.1 AEO56330.1 - 0.081 13.1 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 CoA binding domain MFS_1 PF07690.11 AEO56331.1 - 1.3e-42 145.8 47.5 2.1e-42 145.1 33.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO56331.1 - 6.7e-15 54.6 11.2 6.7e-15 54.6 7.8 2.7 2 1 1 3 3 3 1 Sugar (and other) transporter TIMELESS PF04821.9 AEO56332.1 - 1.8e-95 319.1 0.1 6.8e-95 317.3 0.0 2.1 2 0 0 2 2 2 1 Timeless protein TIMELESS_C PF05029.8 AEO56332.1 - 5.4e-34 118.0 0.0 5.4e-34 118.0 0.0 3.6 2 1 0 3 3 3 2 Timeless protein C terminal region 3HCDH_N PF02737.13 AEO56333.1 - 1.6e-53 180.9 0.1 2.4e-53 180.4 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 AEO56333.1 - 2.5e-33 114.3 0.0 5.7e-33 113.2 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Saccharop_dh PF03435.13 AEO56333.1 - 0.00015 20.8 0.1 0.00021 20.3 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase ApbA PF02558.11 AEO56333.1 - 0.0016 17.8 0.1 0.0061 16.0 0.0 1.9 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.10 AEO56333.1 - 0.0031 17.3 0.1 0.0058 16.4 0.0 1.5 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DAO PF01266.19 AEO56333.1 - 0.0072 15.2 0.0 0.0098 14.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 AEO56333.1 - 0.036 13.2 0.1 0.077 12.1 0.1 1.6 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 AEO56333.1 - 0.069 13.2 0.6 0.14 12.2 0.4 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 AEO56333.1 - 0.11 12.2 0.5 0.21 11.3 0.3 1.5 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 AEO56333.1 - 0.13 12.7 0.9 0.43 11.0 0.7 1.8 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox PF00070.22 AEO56333.1 - 0.13 12.6 0.1 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Homeobox PF00046.24 AEO56334.1 - 1.1e-17 63.4 2.8 2e-17 62.5 2.0 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 AEO56334.1 - 0.0033 17.0 0.1 0.0081 15.8 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain DUF2890 PF11081.3 AEO56334.1 - 0.53 10.3 9.7 1.6 8.7 6.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) HCO3_cotransp PF00955.16 AEO56335.1 - 3.9e-68 230.3 13.3 3.7e-40 138.0 2.7 3.0 2 1 1 3 3 3 3 HCO3- transporter family Peptidase_M41 PF01434.13 AEO56336.1 - 3e-75 252.3 0.0 4.8e-75 251.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 AEO56336.1 - 2.3e-42 144.3 0.0 4.9e-42 143.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 AEO56336.1 - 3.6e-10 39.9 0.0 8.3e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 FtsH Extracellular AAA_22 PF13401.1 AEO56336.1 - 0.001 19.1 0.0 0.036 14.2 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 AEO56336.1 - 0.0018 18.0 0.1 0.0073 16.0 0.0 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 AEO56336.1 - 0.0052 15.8 0.0 0.011 14.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 AEO56336.1 - 0.01 15.5 1.7 0.017 14.8 0.3 2.1 2 0 0 2 2 1 0 Part of AAA domain AAA_2 PF07724.9 AEO56336.1 - 0.011 15.6 0.5 0.029 14.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 AEO56336.1 - 0.012 15.5 0.6 0.13 12.1 0.1 2.8 2 1 1 3 3 3 0 AAA ATPase domain TIP49 PF06068.8 AEO56336.1 - 0.014 14.1 0.0 0.025 13.3 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus IstB_IS21 PF01695.12 AEO56336.1 - 0.023 14.0 0.0 0.059 12.7 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.1 AEO56336.1 - 0.031 15.0 0.1 0.2 12.4 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.1 AEO56336.1 - 0.037 13.4 1.5 0.13 11.6 0.1 2.5 2 1 1 3 3 3 0 AAA domain AAA_14 PF13173.1 AEO56336.1 - 0.054 13.4 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 AEO56336.1 - 0.17 11.7 2.6 0.2 11.5 0.0 2.5 2 0 0 2 2 1 0 AAA domain CobT PF06213.7 AEO56336.1 - 0.52 9.4 7.4 0.14 11.2 2.8 1.7 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Pex14_N PF04695.8 AEO56336.1 - 1.9 8.5 13.3 1.2 9.2 3.9 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Fungal_trans PF04082.13 AEO56337.1 - 2.4e-31 108.5 0.0 5.6e-31 107.3 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO56338.1 - 1.9e-11 43.6 12.0 2.5e-11 43.2 8.3 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mid2 PF04478.7 AEO56339.1 - 4.1e-05 23.0 0.5 0.0002 20.8 0.0 2.2 1 1 1 2 2 2 1 Mid2 like cell wall stress sensor SKG6 PF08693.5 AEO56339.1 - 0.041 13.1 2.1 0.12 11.7 1.4 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.10 AEO56339.1 - 0.046 13.2 0.1 0.085 12.4 0.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 PGAP1 PF07819.8 AEO56340.1 - 6.4e-07 29.1 0.0 1.8e-06 27.6 0.0 1.7 1 1 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 AEO56340.1 - 1.6e-06 27.5 0.0 3.5e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 AEO56340.1 - 4.1e-05 23.3 0.0 7.6e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AEO56340.1 - 0.0013 18.6 2.5 0.0013 18.6 1.8 2.4 3 1 0 3 3 3 1 Alpha/beta hydrolase family UPF0227 PF05728.7 AEO56340.1 - 0.0055 16.4 1.0 0.0084 15.8 0.0 1.7 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) Thioesterase PF00975.15 AEO56340.1 - 0.041 14.1 2.6 0.26 11.4 0.0 2.7 3 0 0 3 3 3 0 Thioesterase domain Lipase_3 PF01764.20 AEO56340.1 - 0.048 13.2 0.0 0.098 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF536 PF04394.9 AEO56340.1 - 0.099 12.3 4.9 0.18 11.5 3.4 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF536 Abhydrolase_3 PF07859.8 AEO56340.1 - 0.11 12.1 0.1 0.31 10.5 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 AEO56340.1 - 0.11 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold LCAT PF02450.10 AEO56340.1 - 0.14 11.1 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Rox3 PF08633.5 AEO56341.1 - 2e-59 201.1 0.3 2.3e-59 200.9 0.2 1.0 1 0 0 1 1 1 1 Rox3 mediator complex subunit Ribosomal_L4 PF00573.17 AEO56342.1 - 2.2e-44 151.1 0.0 2.9e-44 150.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family PBP PF01161.15 AEO56343.1 - 7e-12 45.4 0.0 1.1e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein RhoGAP PF00620.22 AEO56344.1 - 2.4e-13 49.9 0.0 4.4e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain CBS PF00571.23 AEO56345.1 - 2.7e-31 107.0 9.7 2.6e-15 55.9 0.1 4.3 4 0 0 4 4 4 4 CBS domain Arm PF00514.18 AEO56346.1 - 2.5e-70 230.1 28.5 3.4e-13 48.8 0.1 11.2 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 AEO56346.1 - 4.4e-24 84.5 13.4 1.5e-06 28.3 0.1 7.7 2 2 2 6 6 6 5 HEAT repeats HEAT PF02985.17 AEO56346.1 - 3e-20 70.4 12.6 0.053 13.6 0.1 9.4 11 0 0 11 11 10 5 HEAT repeat HEAT_EZ PF13513.1 AEO56346.1 - 1.1e-18 67.1 11.5 0.00026 21.3 0.2 8.5 5 2 4 9 9 9 5 HEAT-like repeat Adaptin_N PF01602.15 AEO56346.1 - 2e-11 42.9 8.2 1.7e-06 26.6 0.2 3.1 2 1 1 3 3 3 2 Adaptin N terminal region KAP PF05804.7 AEO56346.1 - 1.4e-10 39.8 0.4 2.4e-10 39.0 0.3 1.3 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.9 AEO56346.1 - 1.5e-10 40.6 1.6 0.0016 17.6 0.1 3.9 2 1 1 3 3 3 2 V-ATPase subunit H Arm_2 PF04826.8 AEO56346.1 - 2.6e-10 39.8 6.6 0.016 14.3 0.1 3.6 2 1 1 3 3 3 3 Armadillo-like Cnd1 PF12717.2 AEO56346.1 - 0.001 18.9 2.2 7.8 6.3 0.0 4.7 3 2 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Vpu PF00558.14 AEO56346.1 - 0.0024 17.3 0.8 0.0064 16.0 0.1 2.0 2 0 0 2 2 2 1 Vpu protein PUL PF08324.6 AEO56346.1 - 0.004 15.9 1.6 0.013 14.3 0.4 2.4 2 0 0 2 2 2 1 PUL domain HEAT_PBS PF03130.11 AEO56346.1 - 0.0077 16.6 6.4 62 4.4 0.1 6.7 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat Vac14_Fab1_bd PF12755.2 AEO56346.1 - 0.053 13.9 0.1 1.4 9.3 0.0 3.0 2 1 2 4 4 3 0 Vacuolar 14 Fab1-binding region DUF1981 PF09324.5 AEO56346.1 - 0.12 11.8 0.0 10 5.7 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF1981) Peptidase_S24 PF00717.18 AEO56347.1 - 1.8e-07 30.6 0.0 3.9e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 AEO56347.1 - 2.4e-06 27.1 0.0 4.4e-05 23.0 0.0 2.4 2 1 0 2 2 2 1 Signal peptidase, peptidase S26 IF3_C PF00707.17 AEO56348.1 - 7.9e-10 38.3 0.1 1.2e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.1 AEO56348.1 - 0.00019 20.8 0.2 0.0092 15.3 0.2 2.1 1 1 1 2 2 2 2 Mitochondrial translation initiation factor IF-2B PF01008.12 AEO56349.1 - 1.9e-45 155.0 0.0 5.5e-45 153.5 0.0 1.6 1 1 0 1 1 1 1 Initiation factor 2 subunit family Caudo_TAP PF02413.12 AEO56349.1 - 0.36 10.9 2.9 3.8 7.6 0.8 2.3 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein NARP1 PF12569.3 AEO56349.1 - 8.8 4.9 7.8 13 4.4 5.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 COMPASS-Shg1 PF05205.7 AEO56351.1 - 6.6e-27 93.8 0.1 1.6e-26 92.6 0.1 1.7 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 TPT PF03151.11 AEO56352.1 - 2.9e-20 72.4 9.6 2.9e-20 72.4 6.7 3.1 2 1 1 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 AEO56352.1 - 4.7e-05 23.4 29.1 0.0002 21.4 5.7 2.7 3 0 0 3 3 3 2 EamA-like transporter family UAA PF08449.6 AEO56352.1 - 0.00014 20.8 15.6 0.016 14.1 3.6 2.2 2 0 0 2 2 2 2 UAA transporter family UCH PF00443.24 AEO56353.1 - 2.5e-36 125.1 0.0 4.6e-36 124.3 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AEO56353.1 - 0.0041 16.6 0.0 0.01 15.3 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Alb1 PF09135.6 AEO56354.1 - 4.9e-26 91.5 13.3 4.9e-26 91.5 9.2 1.6 1 1 1 2 2 2 1 Alb1 VSG_B PF13206.1 AEO56354.1 - 0.2 10.7 5.5 0.25 10.4 3.8 1.2 1 0 0 1 1 1 0 Trypanosomal VSG domain bZIP_1 PF00170.16 AEO56355.1 - 4.3e-11 42.6 3.4 8.2e-11 41.7 2.3 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 AEO56355.1 - 3.5e-07 29.9 5.2 3.5e-07 29.9 3.6 1.8 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 AEO56355.1 - 0.025 14.8 1.5 0.025 14.8 1.1 2.0 1 1 1 2 2 2 0 bZIP Maf transcription factor Rep_fac-A_3 PF08661.6 AEO56357.1 - 1.1e-21 76.8 0.0 1.2e-21 76.6 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Stomoxyn PF11585.3 AEO56357.1 - 0.068 12.9 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Insect antimicrobial peptide, stomoxyn GATA PF00320.22 AEO56358.1 - 0.00011 21.4 5.9 0.013 14.8 1.4 2.5 2 0 0 2 2 2 2 GATA zinc finger Pyr_redox_2 PF07992.9 AEO56359.1 - 5.2e-11 42.8 0.0 8.9e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AEO56359.1 - 3.5e-10 40.1 0.0 7.1e-08 32.7 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AEO56359.1 - 6.2e-09 36.2 0.1 1.1e-06 28.8 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 AEO56359.1 - 3.1e-05 23.0 0.1 0.00028 19.9 0.0 2.2 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) ThiF PF00899.16 AEO56359.1 - 0.011 15.5 0.1 0.14 12.0 0.0 2.6 3 0 0 3 3 3 0 ThiF family Pribosyltran PF00156.22 AEO56359.1 - 0.034 13.8 0.2 10 5.8 0.0 2.4 2 0 0 2 2 2 0 Phosphoribosyl transferase domain TrkA_N PF02254.13 AEO56359.1 - 0.036 14.0 0.2 1.9 8.5 0.0 2.8 3 0 0 3 3 3 0 TrkA-N domain NAD_binding_9 PF13454.1 AEO56359.1 - 0.091 12.5 0.9 10 5.8 0.0 3.4 3 1 0 3 3 3 0 FAD-NAD(P)-binding Thi4 PF01946.12 AEO56359.1 - 0.11 11.5 0.2 8 5.4 0.0 2.5 2 0 0 2 2 2 0 Thi4 family Bul1_C PF04426.7 AEO56359.1 - 0.2 10.8 0.1 0.35 10.0 0.1 1.3 1 0 0 1 1 1 0 Bul1 C terminus PBP PF01161.15 AEO56360.1 - 1.7e-11 44.1 0.0 2.2e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Peptidase_M14 PF00246.19 AEO56362.1 - 1.8e-71 240.9 0.0 2.3e-71 240.6 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Sec7 PF01369.15 AEO56363.1 - 3.7e-40 137.6 0.0 6.1e-40 136.9 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 AEO56363.1 - 8e-07 29.2 0.4 2.6e-06 27.5 0.1 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 AEO56363.1 - 1.2e-05 25.4 0.1 2.4e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 PH domain SRP72 PF08492.7 AEO56364.1 - 4.2e-16 59.0 10.8 4.2e-16 59.0 7.5 1.9 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_16 PF13432.1 AEO56364.1 - 0.00082 19.9 8.7 0.00082 19.9 6.0 6.7 6 2 2 8 8 8 1 Tetratricopeptide repeat Apc3 PF12895.2 AEO56364.1 - 0.0029 17.7 11.3 0.0086 16.1 1.2 4.0 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 AEO56364.1 - 0.016 15.0 20.0 5.1 7.2 0.2 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_12 PF13424.1 AEO56364.1 - 0.088 12.7 20.4 0.089 12.7 0.0 5.7 4 2 1 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 AEO56364.1 - 0.57 10.9 0.1 0.57 10.9 0.0 9.0 7 3 3 10 10 10 0 Tetratricopeptide repeat TPR_4 PF07721.9 AEO56364.1 - 0.68 10.5 0.1 0.68 10.5 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.1 AEO56364.1 - 0.75 10.1 28.1 1.5 9.2 0.7 7.3 5 3 2 7 7 7 0 Tetratricopeptide repeat DUF1522 PF07482.6 AEO56364.1 - 0.79 9.8 4.9 50 4.1 0.2 3.5 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1522) Abhydrolase_6 PF12697.2 AEO56365.1 - 3.6e-35 121.8 0.2 5.1e-35 121.4 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO56365.1 - 2.3e-21 76.4 0.0 3.5e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AEO56365.1 - 2.3e-14 53.3 0.0 4.2e-14 52.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 AEO56365.1 - 3.4e-06 27.4 0.0 4.3e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.8 AEO56365.1 - 3.7e-06 26.6 0.0 6e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Esterase PF00756.15 AEO56365.1 - 0.0014 18.1 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 Putative esterase DUF915 PF06028.6 AEO56365.1 - 0.026 13.6 0.0 2.6 7.0 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Hydrolase_4 PF12146.3 AEO56365.1 - 0.051 13.4 0.0 0.093 12.5 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase DUF2048 PF09752.4 AEO56365.1 - 0.076 11.8 0.0 1.7 7.4 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2048) Lipase_3 PF01764.20 AEO56365.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_3 PF07859.8 AEO56365.1 - 0.12 11.9 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF676 PF05057.9 AEO56365.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) UPF0227 PF05728.7 AEO56365.1 - 0.15 11.7 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Ribosomal_S3Ae PF01015.13 AEO56366.1 - 1.8e-81 272.1 3.4 2.1e-81 271.9 2.4 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Syntaxin PF00804.20 AEO56366.1 - 0.04 14.0 0.3 0.33 11.1 0.0 2.4 2 1 1 3 3 3 0 Syntaxin GTP_CH_N PF12471.3 AEO56368.1 - 4.5e-92 307.0 0.0 6.4e-92 306.5 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 AEO56368.1 - 3.3e-16 58.9 0.0 5.2e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II Elf1 PF05129.8 AEO56369.1 - 1.2e-29 101.7 1.3 1.6e-29 101.4 0.9 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Cys_rich_CPXG PF14255.1 AEO56369.1 - 0.29 11.0 2.4 0.49 10.2 1.6 1.5 1 0 0 1 1 1 0 Cysteine-rich CPXCG UPRTase PF14681.1 AEO56370.1 - 4.7e-81 270.9 0.0 5.9e-81 270.6 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 AEO56370.1 - 0.00014 21.5 0.0 0.00022 20.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.8 AEO56370.1 - 0.099 12.3 0.2 0.16 11.7 0.1 1.2 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) WAPL PF07814.8 AEO56371.1 - 9e-19 67.4 0.1 1.4e-18 66.7 0.1 1.3 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin DUF2984 PF11203.3 AEO56371.1 - 1.7 8.8 10.7 2.7 8.1 0.1 4.6 5 0 0 5 5 5 0 Protein of unknown function (DUF2984) Ras PF00071.17 AEO56372.1 - 7.1e-47 158.7 0.0 8.1e-47 158.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AEO56372.1 - 2.6e-15 56.9 0.1 3.4e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AEO56372.1 - 7.3e-08 31.8 0.0 8.4e-08 31.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 AEO56372.1 - 3.5e-06 26.5 0.0 2.7e-05 23.6 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 AEO56372.1 - 4.3e-06 26.6 0.0 7.5e-06 25.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 AEO56372.1 - 0.0024 17.1 0.0 0.0032 16.7 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 AEO56372.1 - 0.065 13.1 0.0 0.089 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain tRNA-synt_2b PF00587.20 AEO56373.1 - 7.8e-37 126.4 0.0 1.6e-36 125.5 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 AEO56373.1 - 5.4e-18 64.9 4.8 5.4e-18 64.9 3.3 1.6 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain AIPR PF10592.4 AEO56373.1 - 0.079 12.2 1.6 0.24 10.6 0.5 1.9 2 0 0 2 2 2 0 AIPR protein Peptidase_C78 PF07910.8 AEO56376.1 - 5.6e-66 221.7 0.0 7.8e-66 221.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C47 PF05543.8 AEO56376.1 - 0.098 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Staphopain peptidase C47 Ham1p_like PF01725.11 AEO56377.1 - 7.3e-08 32.0 0.1 8.9e-08 31.7 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Ran-binding PF05508.6 AEO56377.1 - 0.15 10.9 0.1 0.15 10.9 0.1 1.0 1 0 0 1 1 1 0 RanGTP-binding protein AAA_18 PF13238.1 AEO56378.1 - 9.9e-29 100.2 1.9 1.4e-28 99.7 0.1 1.8 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 AEO56378.1 - 4.7e-16 59.7 1.6 9.6e-16 58.6 1.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AEO56378.1 - 1.2e-05 25.1 0.0 0.00059 19.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain ADK PF00406.17 AEO56378.1 - 1.4e-05 24.9 0.1 0.025 14.4 0.0 2.2 1 1 1 2 2 2 2 Adenylate kinase SKI PF01202.17 AEO56378.1 - 3.4e-05 23.7 0.6 0.00015 21.6 0.4 1.8 1 1 0 1 1 1 1 Shikimate kinase AAA_28 PF13521.1 AEO56378.1 - 6.7e-05 22.9 0.1 0.00022 21.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 AEO56378.1 - 0.00081 19.5 0.0 0.003 17.7 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Thymidylate_kin PF02223.12 AEO56378.1 - 0.0034 16.7 1.3 1.8 7.8 0.0 2.3 2 1 0 2 2 2 2 Thymidylate kinase KTI12 PF08433.5 AEO56378.1 - 0.0043 16.2 0.1 0.017 14.3 0.0 1.8 2 0 0 2 2 2 1 Chromatin associated protein KTI12 Cytidylate_kin2 PF13189.1 AEO56378.1 - 0.009 15.9 0.8 0.11 12.4 0.5 2.4 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_16 PF13191.1 AEO56378.1 - 0.016 15.2 0.0 0.034 14.1 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_5 PF07728.9 AEO56378.1 - 0.019 14.6 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) dNK PF01712.14 AEO56378.1 - 0.02 14.8 0.7 0.028 14.3 0.5 1.2 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA_19 PF13245.1 AEO56378.1 - 0.042 13.5 0.2 0.083 12.6 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain Zeta_toxin PF06414.7 AEO56378.1 - 0.049 12.7 0.0 0.14 11.2 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.1 AEO56378.1 - 0.059 13.5 0.4 0.12 12.4 0.3 1.9 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.4 AEO56378.1 - 0.56 9.1 3.7 0.47 9.3 0.4 2.1 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Myosin_head PF00063.16 AEO56379.1 - 1.4e-241 803.4 0.0 1.4e-241 803.4 0.0 1.8 2 0 0 2 2 1 1 Myosin head (motor domain) DIL PF01843.14 AEO56379.1 - 8.9e-35 118.7 4.1 2.3e-34 117.4 2.8 1.8 1 0 0 1 1 1 1 DIL domain IQ PF00612.22 AEO56379.1 - 5.3e-12 44.2 38.4 0.0001 21.5 1.5 6.8 6 0 0 6 6 6 5 IQ calmodulin-binding motif ERM PF00769.14 AEO56379.1 - 0.00043 19.8 20.8 0.00043 19.8 14.4 2.4 2 0 0 2 2 2 1 Ezrin/radixin/moesin family GAS PF13851.1 AEO56379.1 - 0.00087 18.5 25.5 0.021 14.0 17.6 2.5 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding AAA_22 PF13401.1 AEO56379.1 - 0.0031 17.6 0.0 0.015 15.4 0.0 2.2 1 0 0 1 1 1 1 AAA domain Reo_sigmaC PF04582.7 AEO56379.1 - 0.0036 16.5 3.2 0.0049 16.0 1.3 1.8 1 1 1 2 2 2 1 Reovirus sigma C capsid protein FlaC_arch PF05377.6 AEO56379.1 - 0.0044 16.8 0.2 0.0044 16.8 0.1 3.7 4 0 0 4 4 3 1 Flagella accessory protein C (FlaC) AAA_19 PF13245.1 AEO56379.1 - 0.0051 16.5 0.1 0.046 13.4 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain Myosin_N PF02736.14 AEO56379.1 - 0.033 13.8 0.7 0.092 12.4 0.5 1.8 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain CALCOCO1 PF07888.6 AEO56379.1 - 0.063 11.5 16.8 0.11 10.8 11.7 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like AAA_16 PF13191.1 AEO56379.1 - 0.22 11.4 0.0 0.22 11.4 0.0 2.8 2 1 0 2 2 1 0 AAA ATPase domain FUSC PF04632.7 AEO56379.1 - 0.26 9.6 10.6 0.42 8.9 7.3 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Baculo_PEP_C PF04513.7 AEO56379.1 - 0.3 10.9 8.2 2.8 7.7 5.7 2.5 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF812 PF05667.6 AEO56379.1 - 0.94 7.9 29.0 1.5 7.2 20.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) APG6 PF04111.7 AEO56379.1 - 3.8 6.4 27.8 0.95 8.4 15.0 2.4 1 1 1 2 2 2 0 Autophagy protein Apg6 DegQ PF08181.6 AEO56379.1 - 3.9 7.2 7.9 0.34 10.6 0.1 3.2 3 0 0 3 3 2 0 DegQ (SacQ) family EMP24_GP25L PF01105.19 AEO56379.1 - 5.1 6.7 8.6 59 3.3 6.0 2.6 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Hemerythrin PF01814.18 AEO56379.1 - 5.6 7.1 10.5 18 5.4 6.8 2.1 1 1 0 1 1 1 0 Hemerythrin HHE cation binding domain ADIP PF11559.3 AEO56379.1 - 5.8 6.8 35.9 0.098 12.5 3.7 3.3 2 1 1 3 3 2 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.4 AEO56379.1 - 9.4 5.0 20.9 21 3.9 14.5 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 2-Hacid_dh_C PF02826.14 AEO56381.1 - 3.8e-53 179.2 0.0 6.1e-53 178.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 AEO56381.1 - 9.2e-38 128.7 0.0 1.5e-37 128.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 AEO56381.1 - 1.3e-05 25.0 0.1 3.4e-05 23.7 0.1 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 AEO56381.1 - 0.00028 20.7 0.0 0.00067 19.5 0.0 1.6 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ACT PF01842.20 AEO56381.1 - 0.003 16.9 0.1 0.011 15.1 0.1 2.0 1 0 0 1 1 1 1 ACT domain IlvN PF07991.7 AEO56381.1 - 0.0091 15.3 0.1 0.18 11.1 0.0 2.3 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain XdhC_C PF13478.1 AEO56381.1 - 0.065 13.5 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain 3HCDH_N PF02737.13 AEO56381.1 - 0.076 12.6 1.4 1 8.9 0.4 2.7 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAP PF00956.13 AEO56382.1 - 5.9e-89 297.3 7.9 5.9e-89 297.3 5.5 2.0 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) P5-ATPase PF12409.3 AEO56383.1 - 4.7e-41 139.3 0.0 2.2e-40 137.1 0.0 2.2 2 0 0 2 2 2 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.15 AEO56383.1 - 1.6e-29 102.6 0.0 3.4e-29 101.5 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 AEO56383.1 - 7.4e-29 101.2 0.0 1.4e-28 100.4 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 AEO56383.1 - 3.9e-18 66.6 0.0 2.3e-17 64.1 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 AEO56383.1 - 0.0015 17.9 0.0 0.0029 17.0 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 AEO56383.1 - 0.058 13.3 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 AEO56383.1 - 0.06 12.9 0.0 0.99 8.9 0.0 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase NADH_B2 PF14813.1 AEO56384.1 - 0.0013 18.4 0.3 0.0013 18.3 0.2 1.1 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 Pkinase PF00069.20 AEO56385.1 - 7.1e-65 218.7 0.0 8.5e-65 218.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO56385.1 - 5.3e-30 104.3 0.0 6.9e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO56385.1 - 0.0083 15.1 0.0 0.02 13.8 0.0 1.6 2 1 0 2 2 2 1 Kinase-like Stm1_N PF09598.5 AEO56387.1 - 9.5 7.0 11.7 9.6 6.9 3.9 2.3 2 0 0 2 2 2 0 Stm1 Metallophos PF00149.23 AEO56388.1 - 6.2e-38 130.2 0.0 9.1e-38 129.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 AEO56388.1 - 4.4e-31 106.7 0.2 1.1e-30 105.4 0.1 1.7 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_11 PF13414.1 AEO56388.1 - 1.2e-15 56.9 0.1 4.2e-10 39.1 0.0 2.4 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 AEO56388.1 - 3.8e-11 42.0 0.3 0.00012 21.5 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 AEO56388.1 - 1.1e-08 34.3 0.3 0.0043 16.8 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 AEO56388.1 - 0.00054 20.3 0.0 0.33 11.6 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 AEO56388.1 - 0.0056 17.3 0.1 1.6 9.4 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 AEO56388.1 - 0.057 13.8 0.1 0.82 10.2 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Kelch_4 PF13418.1 AEO56388.1 - 0.14 11.9 0.2 0.31 10.8 0.1 1.5 1 0 0 1 1 1 0 Galactose oxidase, central domain DUF4231 PF14015.1 AEO56389.1 - 0.085 12.8 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) DUF4611 PF15387.1 AEO56389.1 - 0.11 12.6 1.1 0.16 12.1 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4611) FH2 PF02181.18 AEO56390.1 - 2e-81 273.7 4.2 2e-81 273.7 2.9 1.7 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.8 AEO56390.1 - 2.1e-66 222.8 0.0 2.1e-66 222.8 0.0 2.2 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 AEO56390.1 - 3.7e-53 179.8 5.9 2.3e-52 177.3 3.0 2.7 1 1 1 2 2 2 1 Diaphanous FH3 Domain Dna2 PF08696.6 AEO56390.1 - 0.96 8.7 4.2 0.28 10.4 0.4 1.9 2 0 0 2 2 2 0 DNA replication factor Dna2 DUF2264 PF10022.4 AEO56391.1 - 4.2e-126 420.4 0.9 5.3e-126 420.1 0.6 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Surf_Ag_VNR PF07244.10 AEO56391.1 - 0.085 13.2 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 Surface antigen variable number repeat Aminotran_5 PF00266.14 AEO56392.1 - 5.2e-28 97.8 0.0 5.4e-19 68.1 0.0 2.0 1 1 1 2 2 2 2 Aminotransferase class-V adh_short_C2 PF13561.1 AEO56393.1 - 8.8e-09 35.4 0.0 1.3e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 AEO56393.1 - 9e-08 32.2 0.0 1.6e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase DUF904 PF06005.7 AEO56393.1 - 0.065 13.5 0.3 0.23 11.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF904) TRAPPC9-Trs120 PF08626.6 AEO56394.1 - 8.1e-133 444.1 0.0 8.6e-109 364.5 0.0 2.5 2 1 0 2 2 2 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Chorismate_bind PF00425.13 AEO56395.1 - 6.1e-66 222.3 0.0 2.9e-60 203.7 0.0 2.6 2 0 0 2 2 2 2 chorismate binding enzyme GATase PF00117.23 AEO56395.1 - 1.8e-22 79.7 0.0 3.6e-21 75.5 0.0 2.5 2 1 0 2 2 2 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 AEO56395.1 - 9.5e-13 48.3 0.0 2.4e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 AEO56395.1 - 4.2e-05 23.0 0.4 0.014 14.8 0.0 2.3 2 0 0 2 2 2 2 Peptidase C26 SR-25 PF10500.4 AEO56395.1 - 0.088 12.2 9.3 0.17 11.3 6.4 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Vps55 PF04133.9 AEO56396.1 - 3.9e-46 155.6 7.4 4.4e-46 155.5 5.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Proteasome PF00227.21 AEO56397.1 - 2.9e-49 166.9 0.0 3.8e-49 166.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 AEO56397.1 - 2.8e-11 42.5 0.2 4.8e-11 41.7 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Lysine_decarbox PF03641.9 AEO56398.1 - 6e-29 100.5 0.0 9.4e-29 99.9 0.0 1.3 1 0 0 1 1 1 1 Possible lysine decarboxylase CLPTM1 PF05602.7 AEO56399.1 - 4.1e-160 533.2 0.0 5e-160 532.9 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) DUF1453 PF07301.6 AEO56399.1 - 0.04 13.7 0.5 0.04 13.7 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1453) PyrI_C PF02748.10 AEO56400.1 - 0.036 13.5 0.2 3.9 6.9 0.0 2.3 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain FUSC PF04632.7 AEO56400.1 - 3.9 5.7 8.4 5.2 5.3 5.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Longin PF13774.1 AEO56401.1 - 2.7e-25 87.7 0.0 4.9e-25 86.9 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 AEO56401.1 - 5e-15 54.8 0.0 8.6e-15 54.1 0.0 1.4 1 0 0 1 1 1 1 Synaptobrevin DUF1664 PF07889.7 AEO56401.1 - 0.0066 16.2 0.9 0.0066 16.2 0.6 1.8 2 1 1 3 3 3 1 Protein of unknown function (DUF1664) DUF4404 PF14357.1 AEO56401.1 - 0.19 12.1 1.0 22 5.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) ASXH PF13919.1 AEO56402.1 - 3.3e-17 62.5 0.0 4.2e-14 52.5 0.0 2.5 1 1 1 2 2 2 2 Asx homology domain Calici_coat PF00915.15 AEO56402.1 - 0.13 11.0 0.8 0.22 10.3 0.5 1.3 1 0 0 1 1 1 0 Calicivirus coat protein FLO_LFY PF01698.11 AEO56402.1 - 0.17 10.7 5.8 0.28 10.0 4.0 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Nbs1_C PF08599.5 AEO56402.1 - 7.6 6.5 6.1 1.3 8.9 0.2 2.4 2 1 1 3 3 3 0 DNA damage repair protein Nbs1 Elong_Iki1 PF10483.4 AEO56403.1 - 3.3e-78 262.8 0.0 3.9e-78 262.6 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 DUF1152 PF06626.7 AEO56403.1 - 0.017 14.2 0.6 0.027 13.5 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1152) DUF1777 PF08648.7 AEO56404.1 - 4.8e-24 85.0 37.9 1.6e-23 83.3 26.3 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1777) CheZ PF04344.8 AEO56404.1 - 0.12 11.9 6.5 0.17 11.5 4.5 1.2 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ Hid1 PF12722.2 AEO56404.1 - 0.25 8.9 1.9 0.22 9.1 1.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DDHD PF02862.12 AEO56404.1 - 1.4 8.6 5.2 2.1 8.1 3.6 1.2 1 0 0 1 1 1 0 DDHD domain Apt1 PF10351.4 AEO56404.1 - 1.5 7.6 6.8 1.7 7.4 4.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain FimP PF09766.4 AEO56404.1 - 1.5 7.7 10.4 2.3 7.1 7.2 1.2 1 0 0 1 1 1 0 Fms-interacting protein RAMP4 PF06624.7 AEO56405.1 - 6.7e-08 31.9 0.0 9.1e-08 31.5 0.0 1.2 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 Adeno_E3_14_5 PF04834.7 AEO56406.1 - 0.12 12.7 0.0 0.14 12.5 0.0 1.2 1 0 0 1 1 1 0 Early E3 14.5 kDa protein Mid1 PF12929.2 AEO56407.1 - 4.5e-128 427.6 0.3 5.2e-128 427.3 0.2 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.17 AEO56407.1 - 0.039 14.3 2.3 0.67 10.3 0.3 2.4 2 0 0 2 2 2 0 Fz domain TB2_DP1_HVA22 PF03134.14 AEO56408.1 - 2.1e-31 107.5 4.8 2.8e-31 107.1 3.3 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF4407 PF14362.1 AEO56408.1 - 0.1 11.5 0.6 6.1 5.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Bestrophin PF01062.16 AEO56408.1 - 9.2 5.1 9.7 68 2.2 6.7 1.9 1 1 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel RFX_DNA_binding PF02257.10 AEO56409.1 - 5.6e-30 103.3 0.1 1.4e-29 102.0 0.1 1.7 1 0 0 1 1 1 1 RFX DNA-binding domain Hydrolase_4 PF12146.3 AEO56410.1 - 1.7e-21 75.8 0.0 5.5e-21 74.1 0.0 1.8 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_6 PF12697.2 AEO56410.1 - 3.8e-19 69.4 2.5 4.8e-19 69.1 1.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO56410.1 - 6.4e-15 55.1 0.0 9.4e-15 54.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO56410.1 - 0.0006 19.4 0.0 0.001 18.6 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 AEO56410.1 - 0.0013 17.9 0.0 0.46 9.6 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 AEO56410.1 - 0.086 11.7 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Lipase_3 PF01764.20 AEO56410.1 - 0.1 12.2 0.0 2.4 7.7 0.0 2.3 2 0 0 2 2 2 0 Lipase (class 3) PAF-AH_p_II PF03403.8 AEO56410.1 - 0.15 10.3 0.0 3.7 5.7 0.0 2.1 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Cation_efflux PF01545.16 AEO56411.1 - 1e-29 103.5 4.3 1.2e-29 103.2 3.0 1.1 1 0 0 1 1 1 1 Cation efflux family Transport_MerF PF11431.3 AEO56411.1 - 1 9.0 5.3 0.17 11.5 0.7 1.9 2 0 0 2 2 2 0 Membrane transport protein MerF EmrE PF13536.1 AEO56411.1 - 3.9 7.6 12.2 0.46 10.6 0.2 3.1 3 1 0 3 3 3 0 Multidrug resistance efflux transporter Glyco_transf_8 PF01501.15 AEO56412.1 - 1.7e-28 99.6 0.1 2.8e-28 98.9 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 AEO56412.1 - 0.01 15.2 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 0 Mannosyltransferase putative HDA2-3 PF11496.3 AEO56413.1 - 6.7e-09 34.9 0.0 1.4e-07 30.6 0.0 2.2 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.19 AEO56413.1 - 3e-06 26.8 0.4 6.7e-06 25.6 0.3 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain MscS_porin PF12795.2 AEO56413.1 - 0.0028 17.0 12.7 0.0028 17.0 8.8 2.7 2 1 1 3 3 3 1 Mechanosensitive ion channel porin domain Myosin_tail_1 PF01576.14 AEO56413.1 - 0.15 9.7 40.5 0.11 10.2 14.2 2.2 1 1 1 2 2 2 0 Myosin tail Seryl_tRNA_N PF02403.17 AEO56413.1 - 0.17 11.9 31.1 0.023 14.6 6.9 3.7 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Tropomyosin_1 PF12718.2 AEO56413.1 - 4.4 7.1 44.2 5.1 6.9 10.2 3.5 2 1 2 4 4 4 0 Tropomyosin like Bacillus_HBL PF05791.6 AEO56413.1 - 4.8 6.5 10.5 0.67 9.3 1.6 2.8 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) AAA_13 PF13166.1 AEO56413.1 - 9.3 4.5 22.7 15 3.8 15.7 1.3 1 0 0 1 1 1 0 AAA domain COX5A PF02284.11 AEO56414.1 - 4.3e-42 142.4 0.5 6.4e-42 141.9 0.4 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va DHC_N1 PF08385.7 AEO56414.1 - 0.034 12.5 0.2 0.72 8.1 0.0 2.0 1 1 1 2 2 2 0 Dynein heavy chain, N-terminal region 1 DUF488 PF04343.8 AEO56414.1 - 0.14 12.4 0.4 1.4 9.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF488 ELO PF01151.13 AEO56415.1 - 3.8e-62 209.8 18.9 4.6e-62 209.5 13.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family p53-inducible11 PF14936.1 AEO56415.1 - 0.16 11.9 1.4 4.1 7.3 0.0 2.7 3 0 0 3 3 3 0 Tumour protein p53-inducible protein 11 Glyco_hydro_61 PF03443.9 AEO56416.1 - 1.3e-61 208.1 0.0 1.3e-61 208.1 0.0 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 AEO56416.1 - 3.5e-12 45.7 9.7 1.1e-11 44.1 6.7 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain Glycogen_syn PF05693.8 AEO56421.1 - 0 1071.4 0.0 0 1071.1 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 AEO56421.1 - 1.5e-06 27.7 0.0 0.0084 15.5 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 AEO56421.1 - 4.9e-05 23.5 0.0 0.00012 22.2 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.6 AEO56421.1 - 0.0001 21.8 0.1 0.00023 20.7 0.1 1.6 1 0 0 1 1 1 1 Starch synthase catalytic domain Bac_luciferase PF00296.15 AEO56423.1 - 7.6e-65 219.0 5.6 1.1e-64 218.5 3.9 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase SSF PF00474.12 AEO56424.1 - 5e-18 64.9 32.4 5e-18 64.9 22.4 1.4 2 0 0 2 2 2 1 Sodium:solute symporter family DUF4179 PF13786.1 AEO56424.1 - 2.8 8.2 9.8 0.75 10.0 0.8 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) FlgN PF05130.7 AEO56426.1 - 0.0051 17.0 1.4 0.0081 16.4 1.0 1.4 1 0 0 1 1 1 1 FlgN protein APG6 PF04111.7 AEO56426.1 - 0.0056 15.7 0.5 0.0069 15.4 0.3 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 OmpH PF03938.9 AEO56426.1 - 0.036 13.9 0.4 0.047 13.6 0.3 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1599 PF07659.6 AEO56426.1 - 0.086 12.9 2.6 5.7 7.0 0.1 2.3 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1599) DUF1664 PF07889.7 AEO56426.1 - 0.15 11.8 0.3 0.23 11.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Fzo_mitofusin PF04799.8 AEO56426.1 - 0.2 11.0 1.1 0.29 10.5 0.8 1.2 1 0 0 1 1 1 0 fzo-like conserved region DUF724 PF05266.9 AEO56426.1 - 0.22 11.1 3.0 0.61 9.6 2.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF724) CALCOCO1 PF07888.6 AEO56426.1 - 1.5 7.0 9.3 1.9 6.7 6.5 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2852 PF11014.3 AEO56426.1 - 2.5 8.0 6.2 2.6 8.0 3.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) Nucleocapsid-N PF11030.3 AEO56428.1 - 6 6.6 8.4 0.17 11.7 1.1 1.7 1 1 1 2 2 2 0 Nucleocapsid protein N Pkinase PF00069.20 AEO56429.1 - 3.5e-71 239.3 0.0 5.2e-71 238.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO56429.1 - 4.4e-35 120.9 0.0 1.8e-34 119.0 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 AEO56429.1 - 0.0021 17.1 0.1 0.0039 16.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 AEO56429.1 - 0.0026 16.7 0.0 0.0043 16.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pmp3 PF01679.12 AEO56431.1 - 8.1e-17 60.6 14.3 9.7e-17 60.4 9.9 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator RseC_MucC PF04246.7 AEO56431.1 - 0.023 14.2 0.3 0.029 13.9 0.2 1.1 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC TPPK_C PF12555.3 AEO56431.1 - 0.042 13.5 3.3 0.061 13.0 2.3 1.2 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal zf-RanBP PF00641.13 AEO56432.1 - 2.9e-18 64.6 13.7 9.5e-11 40.6 1.3 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 AEO56432.1 - 1.8e-08 33.9 0.0 3.4e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.19 AEO56432.1 - 3e-07 30.8 0.0 4.9e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Exonuclease RRM_6 PF14259.1 AEO56432.1 - 7.7e-06 25.7 0.0 1.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DZR PF12773.2 AEO56432.1 - 4.1 7.2 11.1 0.77 9.6 0.8 2.4 2 0 0 2 2 2 0 Double zinc ribbon Ycf1 PF05758.7 AEO56433.1 - 0.84 7.2 6.3 1.6 6.3 4.3 1.3 1 0 0 1 1 1 0 Ycf1 Prog_receptor PF02161.10 AEO56433.1 - 2 7.1 4.5 4 6.1 3.1 1.4 1 0 0 1 1 1 0 Progesterone receptor RNase_H2_suC PF08615.6 AEO56433.1 - 2.9 7.7 5.7 16 5.3 0.6 2.4 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) WD40 PF00400.27 AEO56434.1 - 3.9e-36 121.6 2.7 3.6e-08 32.9 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 AEO56434.1 - 7.7e-31 105.8 0.2 1.8e-30 104.6 0.2 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex XRN_N PF03159.13 AEO56435.1 - 1.2e-86 290.0 0.1 2.2e-86 289.1 0.0 1.5 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus Ribosomal_L35Ae PF01247.13 AEO56435.1 - 0.026 14.2 0.2 27 4.6 0.1 3.3 3 0 0 3 3 3 0 Ribosomal protein L35Ae R3H PF01424.17 AEO56435.1 - 0.029 14.0 0.0 0.076 12.7 0.0 1.8 1 0 0 1 1 1 0 R3H domain SPC22 PF04573.7 AEO56436.1 - 7e-32 110.0 0.1 2.1e-21 75.9 0.0 2.1 2 0 0 2 2 2 2 Signal peptidase subunit Hid1 PF12722.2 AEO56437.1 - 1.1e-248 827.5 0.0 4.9e-248 825.3 0.0 1.8 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 AEO56437.1 - 2.7e-78 263.7 0.0 5.5e-76 256.1 0.0 2.0 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Phospho_p8 PF10195.4 AEO56438.1 - 0.061 13.1 0.1 0.093 12.6 0.1 1.2 1 0 0 1 1 1 0 DNA-binding nuclear phosphoprotein p8 NPCC PF08058.6 AEO56439.1 - 3.5e-35 120.9 0.1 1.1e-34 119.3 0.1 1.7 1 1 0 1 1 1 1 Nuclear pore complex component AMP-binding PF00501.23 AEO56440.1 - 2.1e-15 56.0 0.1 3.5e-09 35.5 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme MCM PF00493.18 AEO56441.1 - 6.7e-143 475.4 0.1 8.9e-143 475.0 0.1 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 AEO56441.1 - 3.1e-17 63.1 0.8 6.6e-17 62.1 0.2 1.8 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 AEO56441.1 - 7e-07 28.6 0.0 0.0002 20.5 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 AEO56441.1 - 1.9e-05 24.3 0.0 4.3e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 AEO56441.1 - 0.00026 20.6 0.1 0.0013 18.3 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_2 PF13335.1 AEO56441.1 - 0.035 14.4 2.4 0.06 13.7 0.8 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 AEO56441.1 - 0.046 13.1 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.24 AEO56441.1 - 0.085 13.0 0.1 0.35 11.0 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Vps54 PF07928.7 AEO56442.1 - 1.2e-46 158.1 0.1 3e-46 156.9 0.0 1.7 1 0 0 1 1 1 1 Vps54-like protein DUF2450 PF10475.4 AEO56442.1 - 4.8e-06 25.6 0.6 1.6e-05 24.0 0.4 1.8 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Sec8_exocyst PF04048.9 AEO56442.1 - 0.0033 17.0 0.3 0.13 11.9 0.1 2.7 3 0 0 3 3 3 1 Sec8 exocyst complex component specific domain zf-C4H2 PF10146.4 AEO56442.1 - 0.088 12.8 1.1 0.41 10.6 0.0 2.5 2 0 0 2 2 2 0 Zinc finger-containing protein DUF904 PF06005.7 AEO56442.1 - 0.12 12.7 1.3 0.77 10.0 0.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF904) COG2 PF06148.6 AEO56442.1 - 0.16 11.8 2.6 0.38 10.6 0.7 2.4 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 LUC7 PF03194.10 AEO56442.1 - 0.23 10.9 2.8 0.3 10.5 0.7 2.0 2 0 0 2 2 2 0 LUC7 N_terminus APC8 PF04049.8 AEO56443.1 - 1.6e-51 173.7 1.4 3.9e-51 172.5 0.0 2.2 3 0 0 3 3 3 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.23 AEO56443.1 - 5.1e-20 70.1 10.6 0.00034 20.0 0.0 8.3 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.1 AEO56443.1 - 4.4e-18 64.6 16.1 4.5e-08 32.6 0.2 7.2 5 2 2 7 7 7 4 TPR repeat TPR_8 PF13181.1 AEO56443.1 - 1.2e-16 59.1 6.1 0.0048 16.5 0.0 8.0 6 1 2 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.12 AEO56443.1 - 3.5e-12 45.2 33.2 0.14 12.1 0.3 10.1 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_14 PF13428.1 AEO56443.1 - 2.8e-10 39.8 15.7 0.065 13.9 0.0 8.9 6 1 3 9 9 9 2 Tetratricopeptide repeat TPR_12 PF13424.1 AEO56443.1 - 4.6e-10 39.2 23.3 0.023 14.6 0.5 7.3 6 1 3 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.1 AEO56443.1 - 2e-06 28.3 22.1 3.5e-05 24.3 0.2 7.3 6 2 2 8 8 7 1 Tetratricopeptide repeat TPR_17 PF13431.1 AEO56443.1 - 2.5e-06 27.2 5.4 2.5 8.5 0.0 6.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 AEO56443.1 - 4.3e-06 26.1 10.7 0.1 12.4 0.0 6.0 7 0 0 7 7 6 2 Tetratricopeptide repeat Apc3 PF12895.2 AEO56443.1 - 3.8e-05 23.7 9.2 0.62 10.2 0.1 5.9 3 1 4 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 AEO56443.1 - 0.00032 20.4 11.7 0.01 15.6 0.1 5.0 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 AEO56443.1 - 0.0065 16.7 17.2 2.6 8.4 0.2 7.1 6 2 1 7 7 7 2 Tetratricopeptide repeat DUF4398 PF14346.1 AEO56443.1 - 0.0087 16.0 1.3 0.028 14.4 0.9 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4398) ChAPs PF09295.5 AEO56443.1 - 0.022 13.5 0.0 1.5 7.4 0.0 2.2 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF3856 PF12968.2 AEO56443.1 - 0.051 13.4 2.2 1.5 8.6 0.1 3.3 2 1 1 3 3 3 0 Domain of Unknown Function (DUF3856) MIT PF04212.13 AEO56443.1 - 0.06 13.2 1.5 0.51 10.2 0.0 3.4 3 0 0 3 3 2 0 MIT (microtubule interacting and transport) domain DUF1955 PF09205.5 AEO56443.1 - 0.12 11.9 0.0 0.42 10.1 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1955) TPR_6 PF13174.1 AEO56443.1 - 0.33 11.5 25.8 0.7 10.4 0.3 9.3 10 1 0 10 10 10 0 Tetratricopeptide repeat TPR_10 PF13374.1 AEO56443.1 - 5.1 7.1 12.8 15 5.6 0.0 5.0 4 1 1 5 5 4 0 Tetratricopeptide repeat polyprenyl_synt PF00348.12 AEO56444.1 - 1.3e-70 237.2 0.0 1.5e-70 236.9 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Homeobox PF00046.24 AEO56444.1 - 0.75 9.4 2.6 0.58 9.8 0.1 2.1 3 0 0 3 3 3 0 Homeobox domain PH PF00169.24 AEO56445.1 - 0.046 13.9 0.3 0.092 12.9 0.2 1.4 1 0 0 1 1 1 0 PH domain RmlD_sub_bind PF04321.12 AEO56446.1 - 2.2e-52 177.7 0.0 2.8e-52 177.3 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 AEO56446.1 - 5.4e-24 84.9 0.0 1.9e-22 79.8 0.0 2.0 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 AEO56446.1 - 2.4e-12 46.3 0.0 2.1e-08 33.3 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 AEO56446.1 - 9e-10 37.7 0.0 6.8e-09 34.8 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 AEO56446.1 - 2.2e-08 33.3 0.0 0.00012 21.1 0.0 3.0 3 0 0 3 3 3 2 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 AEO56446.1 - 3.4e-05 23.9 0.4 7.2e-05 22.8 0.3 1.6 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 AEO56446.1 - 0.0038 17.1 1.3 0.21 11.4 0.2 2.4 1 1 1 2 2 2 1 short chain dehydrogenase NmrA PF05368.8 AEO56446.1 - 0.0038 16.5 1.3 0.29 10.3 1.0 2.9 2 1 0 2 2 2 1 NmrA-like family KR PF08659.5 AEO56446.1 - 0.13 11.8 1.4 15 5.1 0.1 2.5 1 1 0 2 2 2 0 KR domain 6PF2K PF01591.13 AEO56447.1 - 4e-61 205.9 0.0 5.3e-61 205.5 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 AEO56447.1 - 2.8e-22 79.5 0.4 4.5e-22 78.8 0.3 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 AEO56447.1 - 0.0005 19.9 0.0 0.0023 17.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 AEO56447.1 - 0.0042 17.8 0.2 0.052 14.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.5 AEO56447.1 - 0.027 13.6 0.0 0.052 12.7 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 APS_kinase PF01583.15 AEO56447.1 - 0.1 12.2 0.0 1.5 8.4 0.0 2.1 1 1 0 1 1 1 0 Adenylylsulphate kinase Porin_3 PF01459.17 AEO56448.1 - 4.5e-82 275.4 1.5 5.2e-82 275.2 1.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin UCH_1 PF13423.1 AEO56449.1 - 2.1e-52 178.4 0.0 3.9e-52 177.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.24 AEO56449.1 - 7.3e-13 48.2 0.0 1.8e-12 46.9 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Acyl-CoA_dh_1 PF00441.19 AEO56450.1 - 2e-29 102.6 1.4 3.4e-29 101.8 1.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 AEO56450.1 - 4.7e-16 58.0 0.0 1.2e-15 56.7 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 AEO56450.1 - 2.2e-14 53.8 4.0 2.7e-14 53.5 1.2 2.0 1 1 1 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 AEO56450.1 - 4.6e-12 46.5 0.0 1.1e-11 45.3 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain DUF2247 PF10004.4 AEO56450.1 - 0.13 11.9 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) TGS PF02824.16 AEO56452.1 - 1.5e-20 72.7 0.1 2.6e-20 71.9 0.1 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 AEO56452.1 - 1.7e-19 69.8 0.1 5.7e-19 68.1 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AEO56452.1 - 1.3e-12 47.2 0.0 2.1e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 AEO56452.1 - 2.7e-05 24.0 0.3 0.025 14.3 0.0 2.6 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 AEO56452.1 - 0.0012 19.2 0.0 0.0032 17.9 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein ArgK PF03308.11 AEO56452.1 - 0.043 12.5 0.4 0.11 11.2 0.1 1.8 2 0 0 2 2 2 0 ArgK protein MCM PF00493.18 AEO56452.1 - 0.064 12.0 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family NACHT PF05729.7 AEO56453.1 - 2.5e-06 27.2 0.4 5.9e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 NACHT domain WD40 PF00400.27 AEO56453.1 - 0.00098 18.9 0.0 1.1 9.2 0.0 4.7 4 0 0 4 4 4 1 WD domain, G-beta repeat dCMP_cyt_deam_1 PF00383.17 AEO56455.1 - 9.1e-13 47.7 0.0 1.2e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 AEO56455.1 - 0.00074 19.1 0.0 0.0013 18.3 0.0 1.5 1 1 0 1 1 1 1 APOBEC-like N-terminal domain Fructosamin_kin PF03881.9 AEO56456.1 - 1.6e-30 106.0 0.0 1.7e-30 105.9 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 AEO56456.1 - 0.00023 20.9 0.0 0.00025 20.8 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family RRM_1 PF00076.17 AEO56458.1 - 1.5e-09 37.3 0.0 2.7e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO56458.1 - 2e-07 30.7 0.0 4e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO56458.1 - 2.1e-05 24.3 0.1 4.5e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 AEO56458.1 - 0.00016 21.3 0.0 0.00031 20.4 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 AEO56458.1 - 0.059 13.0 0.7 0.12 12.1 0.5 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) UreF PF01730.11 AEO56459.1 - 2.9e-14 53.4 0.1 4.6e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 UreF Late_protein_L2 PF00513.13 AEO56459.1 - 0.041 12.7 0.3 0.059 12.2 0.2 1.2 1 0 0 1 1 1 0 Late Protein L2 Cut12 PF11500.3 AEO56460.1 - 3.7e-44 150.0 17.0 3.7e-44 150.0 11.8 4.2 4 1 0 4 4 4 1 Spindle pole body formation-associated protein Hormone_1 PF00103.15 AEO56460.1 - 9.3 5.5 10.8 4.6 6.5 1.4 2.6 2 1 0 2 2 2 0 Somatotropin hormone family Pkinase PF00069.20 AEO56461.1 - 2.2e-70 236.7 0.0 2.1e-31 109.0 0.0 4.4 3 1 0 3 3 3 3 Protein kinase domain HGTP_anticodon2 PF12745.2 AEO56461.1 - 4.8e-52 176.7 0.4 4.8e-52 176.7 0.2 2.4 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase_Tyr PF07714.12 AEO56461.1 - 8.8e-45 152.7 0.0 3e-17 62.5 0.0 3.4 3 0 0 3 3 3 3 Protein tyrosine kinase tRNA-synt_His PF13393.1 AEO56461.1 - 1.5e-12 47.2 0.9 4.9e-12 45.5 0.0 2.2 2 1 0 2 2 2 1 Histidyl-tRNA synthetase RWD PF05773.17 AEO56461.1 - 2e-12 47.0 0.1 5.9e-12 45.4 0.0 1.9 1 0 0 1 1 1 1 RWD domain Kinase-like PF14531.1 AEO56461.1 - 1.3e-05 24.3 0.0 7.7e-05 21.7 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 AEO56461.1 - 0.0004 20.1 2.2 0.49 10.0 0.0 3.2 3 0 0 3 3 3 2 Phosphotransferase enzyme family Sporozoite_P67 PF05642.6 AEO56461.1 - 2.1 6.1 6.5 1.5 6.5 2.4 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen NOA36 PF06524.7 AEO56461.1 - 4.4 6.4 13.3 8.5 5.5 9.2 1.4 1 0 0 1 1 1 0 NOA36 protein UQ_con PF00179.21 AEO56462.1 - 4.9e-36 123.2 0.0 6.2e-36 122.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AEO56462.1 - 0.0028 17.3 0.0 0.014 15.1 0.0 2.1 1 1 0 1 1 1 1 Prokaryotic E2 family B DUF948 PF06103.6 AEO56463.1 - 0.19 11.6 0.2 1.9 8.3 0.0 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Cu-oxidase_3 PF07732.10 AEO56464.1 - 1.8e-11 43.7 0.0 5.2e-07 29.4 0.0 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 AEO56464.1 - 1.4e-06 27.8 0.1 0.0022 17.5 0.0 2.9 2 1 0 2 2 2 2 Multicopper oxidase Cupredoxin_1 PF13473.1 AEO56464.1 - 0.025 14.4 0.0 0.96 9.3 0.0 2.4 3 0 0 3 3 3 0 Cupredoxin-like domain Phage-tail_3 PF13550.1 AEO56464.1 - 0.081 12.6 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative phage tail protein Copper-bind PF00127.15 AEO56464.1 - 0.1 12.8 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family DUF410 PF04190.8 AEO56465.1 - 2.9e-46 158.1 0.0 3.4e-46 157.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) VirE3 PF06661.6 AEO56465.1 - 0.075 12.1 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 VirE3 Herpes_IE1 PF07340.6 AEO56466.1 - 0.11 10.9 0.0 0.12 10.7 0.0 1.0 1 0 0 1 1 1 0 Cytomegalovirus IE1 protein CRA_rpt PF07046.6 AEO56466.1 - 0.19 11.7 1.6 0.31 11.0 1.1 1.2 1 0 0 1 1 1 0 Cytoplasmic repetitive antigen (CRA) like repeat DNA_pol_B PF00136.16 AEO56467.1 - 7.9e-146 486.5 4.0 1e-145 486.1 2.8 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 AEO56467.1 - 1.3e-79 267.3 0.1 2.9e-79 266.2 0.1 1.6 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 AEO56467.1 - 6.7e-13 48.4 4.3 1.7e-12 47.1 3.0 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.1 AEO56467.1 - 0.00044 20.1 0.2 0.0034 17.2 0.1 2.6 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_2 PF03175.8 AEO56467.1 - 0.002 16.9 1.1 0.07 11.7 0.0 2.7 3 0 0 3 3 3 1 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.4 AEO56467.1 - 0.0051 16.3 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DUF2614 PF11023.3 AEO56467.1 - 0.15 11.8 0.1 0.3 10.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2614) C1_1 PF00130.17 AEO56467.1 - 0.86 9.3 10.0 0.36 10.5 0.5 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) GMC_oxred_C PF05199.8 AEO56468.1 - 1.2e-09 38.5 2.2 5.4e-09 36.4 0.1 2.8 3 0 0 3 3 3 1 GMC oxidoreductase GMC_oxred_N PF00732.14 AEO56468.1 - 1.5e-09 37.4 0.2 1e-08 34.7 0.1 2.1 1 1 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 AEO56468.1 - 5.3e-05 22.2 0.1 9.4e-05 21.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 AEO56468.1 - 0.0023 17.0 0.5 0.0049 16.0 0.3 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AEO56468.1 - 0.005 16.8 0.5 0.021 14.8 0.3 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 AEO56468.1 - 0.0087 14.9 1.0 0.022 13.6 0.2 2.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.17 AEO56468.1 - 0.013 14.3 0.1 0.019 13.8 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 AEO56468.1 - 0.036 13.9 0.2 0.036 13.9 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 AEO56468.1 - 0.05 12.6 0.1 0.084 11.9 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 AEO56468.1 - 0.075 11.9 0.0 0.16 10.8 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.9 AEO56468.1 - 0.083 11.3 0.1 0.14 10.6 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 AEO56468.1 - 0.27 11.6 1.3 0.41 11.0 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ELFV_dehydrog PF00208.16 AEO56469.1 - 6.4e-82 274.8 2.2 7.8e-82 274.5 1.5 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 AEO56469.1 - 1.4e-48 163.8 0.0 9.7e-48 161.0 0.0 2.1 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.1 AEO56469.1 - 0.017 15.3 0.2 0.047 13.9 0.1 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 AEO56469.1 - 0.024 14.1 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Ferritin_2 PF13668.1 AEO56470.1 - 6.3e-41 139.5 0.8 1e-40 138.8 0.5 1.4 1 0 0 1 1 1 1 Ferritin-like domain RNB PF00773.14 AEO56471.1 - 4.3e-77 259.5 0.0 1.2e-76 258.1 0.0 1.8 2 0 0 2 2 2 1 RNB domain DUF4239 PF14023.1 AEO56471.1 - 0.021 14.2 0.2 0.046 13.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Tis11B_N PF04553.7 AEO56471.1 - 0.052 13.7 1.9 0.13 12.4 0.5 2.2 2 0 0 2 2 2 0 Tis11B like protein, N terminus GLE1 PF07817.8 AEO56472.1 - 2.2e-23 82.5 0.0 2.7e-22 78.9 0.0 2.1 1 1 0 1 1 1 1 GLE1-like protein Orbi_VP1 PF05788.7 AEO56472.1 - 0.025 11.8 0.0 0.035 11.3 0.0 1.1 1 0 0 1 1 1 0 Orbivirus RNA-dependent RNA polymerase (VP1) DUF605 PF04652.11 AEO56472.1 - 0.3 10.4 17.6 0.47 9.7 12.2 1.3 1 0 0 1 1 1 0 Vta1 like Syntaxin-6_N PF09177.6 AEO56473.1 - 2.3e-25 88.8 0.3 6.9e-25 87.2 0.0 1.8 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 AEO56473.1 - 2.9e-13 49.2 3.9 2.9e-13 49.2 2.7 2.7 3 0 0 3 3 3 1 SNARE domain Myosin_tail_1 PF01576.14 AEO56473.1 - 0.26 8.9 3.3 2.7 5.5 0.1 2.0 2 0 0 2 2 2 0 Myosin tail Filament PF00038.16 AEO56473.1 - 0.3 10.5 3.4 1.1 8.6 0.4 2.4 2 1 0 2 2 2 0 Intermediate filament protein Metal_resist PF13801.1 AEO56473.1 - 0.44 10.5 5.1 2.8 7.9 0.5 2.6 1 1 1 2 2 2 0 Heavy-metal resistance Pro_isomerase PF00160.16 AEO56474.1 - 1.5e-47 161.6 1.1 1.8e-47 161.4 0.8 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ATP-synt_S1 PF05827.7 AEO56475.1 - 5.8e-41 140.6 0.0 8.9e-41 140.0 0.0 1.3 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Tropomyosin_1 PF12718.2 AEO56476.1 - 8.8e-50 168.2 35.3 1e-49 168.0 24.4 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 AEO56476.1 - 2e-08 33.6 35.4 7e-05 22.0 9.0 3.0 1 1 2 3 3 3 3 Tropomyosin CENP-F_leu_zip PF10473.4 AEO56476.1 - 7.6e-05 22.5 35.5 0.00068 19.5 3.0 2.7 1 1 2 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.6 AEO56476.1 - 0.00037 19.2 13.8 0.00037 19.2 9.6 2.0 1 1 1 2 2 2 1 Spc7 kinetochore protein BRE1 PF08647.6 AEO56476.1 - 0.00044 20.1 28.4 0.01 15.8 11.6 2.2 2 0 0 2 2 2 2 BRE1 E3 ubiquitin ligase ATG16 PF08614.6 AEO56476.1 - 0.00052 19.8 30.7 0.23 11.2 12.2 2.2 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) Cast PF10174.4 AEO56476.1 - 0.00085 17.5 30.2 0.00095 17.3 20.9 1.0 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone Myosin_tail_1 PF01576.14 AEO56476.1 - 0.00095 17.0 34.8 0.0011 16.7 24.1 1.1 1 0 0 1 1 1 1 Myosin tail Mod_r PF07200.8 AEO56476.1 - 0.0016 18.3 27.4 0.17 11.7 13.1 2.1 1 1 1 2 2 2 2 Modifier of rudimentary (Mod(r)) protein HALZ PF02183.13 AEO56476.1 - 0.0039 16.8 1.6 0.0039 16.8 1.1 5.1 4 3 1 5 5 5 2 Homeobox associated leucine zipper APG6 PF04111.7 AEO56476.1 - 0.0047 16.0 35.7 0.19 10.7 10.0 2.1 1 1 1 2 2 2 2 Autophagy protein Apg6 NPV_P10 PF05531.7 AEO56476.1 - 0.0051 17.0 12.1 1.2 9.4 0.1 3.2 1 1 2 3 3 3 2 Nucleopolyhedrovirus P10 protein DivIC PF04977.10 AEO56476.1 - 0.0066 15.9 5.2 0.0066 15.9 3.6 4.4 1 1 4 5 5 5 1 Septum formation initiator GAS PF13851.1 AEO56476.1 - 0.0072 15.5 33.5 0.13 11.4 15.5 2.2 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding ERM PF00769.14 AEO56476.1 - 0.012 15.1 38.6 0.033 13.7 11.0 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family TMF_TATA_bd PF12325.3 AEO56476.1 - 0.014 15.1 29.3 0.031 14.0 13.1 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding BLOC1_2 PF10046.4 AEO56476.1 - 0.015 15.4 22.7 0.052 13.6 5.1 3.5 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 KLRAQ PF10205.4 AEO56476.1 - 0.019 14.9 11.4 0.019 14.9 7.9 2.8 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein Syntaxin-6_N PF09177.6 AEO56476.1 - 0.023 15.1 19.1 0.79 10.1 2.1 2.8 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Laminin_II PF06009.7 AEO56476.1 - 0.033 13.9 20.7 0.07 12.8 1.9 2.4 1 1 1 2 2 2 0 Laminin Domain II PilJ PF13675.1 AEO56476.1 - 0.04 14.2 13.9 0.61 10.4 3.5 2.6 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term TMF_DNA_bd PF12329.3 AEO56476.1 - 0.041 13.6 37.7 0.1 12.4 12.4 3.3 1 1 3 4 4 4 0 TATA element modulatory factor 1 DNA binding DUF4200 PF13863.1 AEO56476.1 - 0.05 13.5 36.6 0.78 9.7 9.8 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) ADIP PF11559.3 AEO56476.1 - 0.077 12.9 33.4 0.26 11.1 8.7 3.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 AEO56476.1 - 0.082 12.5 33.3 4.7 6.7 23.1 2.1 1 1 0 1 1 1 0 IncA protein AAA_13 PF13166.1 AEO56476.1 - 0.1 11.0 23.0 0.14 10.5 15.9 1.2 1 0 0 1 1 1 0 AAA domain CCDC155 PF14662.1 AEO56476.1 - 0.12 12.0 36.1 0.41 10.2 12.2 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 HOOK PF05622.7 AEO56476.1 - 0.16 9.7 26.2 0.19 9.5 18.2 1.1 1 0 0 1 1 1 0 HOOK protein NABP PF07990.7 AEO56476.1 - 0.18 11.0 4.7 0.2 10.8 3.2 1.1 1 0 0 1 1 1 0 Nucleic acid binding protein NABP LPP PF04728.8 AEO56476.1 - 0.21 11.4 2.8 7.4 6.4 0.1 2.9 2 2 1 3 3 3 0 Lipoprotein leucine-zipper HAP1_N PF04849.8 AEO56476.1 - 0.25 10.2 30.5 0.42 9.5 21.1 1.7 1 1 0 1 1 1 0 HAP1 N-terminal conserved region bZIP_1 PF00170.16 AEO56476.1 - 0.26 11.2 32.5 1.2 9.1 3.2 5.2 1 1 4 5 5 5 0 bZIP transcription factor DUF4201 PF13870.1 AEO56476.1 - 0.37 10.2 26.2 0.19 11.1 4.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Filament PF00038.16 AEO56476.1 - 0.39 10.1 29.5 2.5 7.4 3.4 2.1 1 1 1 2 2 2 0 Intermediate filament protein WXG100 PF06013.7 AEO56476.1 - 0.43 10.6 18.4 2.9 7.9 0.5 3.5 2 1 1 3 3 3 0 Proteins of 100 residues with WXG Reo_sigmaC PF04582.7 AEO56476.1 - 0.52 9.4 3.8 6.5 5.8 0.3 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein IFT46_B_C PF12317.3 AEO56476.1 - 0.55 9.5 9.9 0.044 13.1 2.1 1.9 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal Atg14 PF10186.4 AEO56476.1 - 0.56 9.1 27.3 0.26 10.2 11.8 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Vps5 PF09325.5 AEO56476.1 - 0.69 9.1 25.4 0.045 12.9 6.4 2.9 1 1 2 3 3 3 0 Vps5 C terminal like Fmp27_WPPW PF10359.4 AEO56476.1 - 0.71 8.2 24.5 0.064 11.6 5.2 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Fib_alpha PF08702.5 AEO56476.1 - 0.77 9.8 19.8 0.6 10.2 2.7 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF3166 PF11365.3 AEO56476.1 - 0.8 10.1 19.6 6.5 7.2 8.6 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3166) DUF972 PF06156.8 AEO56476.1 - 0.83 10.0 26.9 1.7 8.9 10.7 3.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF869 PF05911.6 AEO56476.1 - 0.88 7.7 26.3 4.5 5.3 18.2 1.9 1 1 0 1 1 1 0 Plant protein of unknown function (DUF869) TMP_2 PF06791.8 AEO56476.1 - 0.96 9.0 5.8 0.31 10.6 1.8 1.7 1 1 0 2 2 2 0 Prophage tail length tape measure protein Herpes_capsid PF06112.6 AEO56476.1 - 1.1 9.3 4.1 2.5 8.1 0.5 2.3 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein FUSC PF04632.7 AEO56476.1 - 1.1 7.5 7.5 1.2 7.4 5.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Jnk-SapK_ap_N PF09744.4 AEO56476.1 - 1.2 9.1 27.9 0.3 11.0 10.9 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 FlaC_arch PF05377.6 AEO56476.1 - 1.2 9.1 20.4 4.9 7.1 0.1 4.2 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) Nsp1_C PF05064.8 AEO56476.1 - 1.2 8.7 22.5 0.2 11.3 6.5 2.6 1 1 1 2 2 2 0 Nsp1-like C-terminal region Laminin_I PF06008.9 AEO56476.1 - 1.2 8.3 27.6 0.25 10.6 5.7 2.3 1 1 1 2 2 2 0 Laminin Domain I Seryl_tRNA_N PF02403.17 AEO56476.1 - 1.3 9.1 30.3 0.62 10.1 7.2 3.2 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF3450 PF11932.3 AEO56476.1 - 1.6 7.9 28.2 3.4 6.8 9.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) WEMBL PF05701.6 AEO56476.1 - 1.9 6.8 36.4 52 2.1 25.2 2.0 1 1 0 1 1 1 0 Weak chloroplast movement under blue light MbeD_MobD PF04899.7 AEO56476.1 - 2 8.4 16.0 1.4 8.8 1.0 3.3 2 2 1 3 3 3 0 MbeD/MobD like DUF342 PF03961.8 AEO56476.1 - 2 6.7 27.5 1.1 7.5 5.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF3287 PF11690.3 AEO56476.1 - 2.1 8.4 12.6 1.3 9.1 2.7 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) Lebercilin PF15619.1 AEO56476.1 - 2.2 7.6 34.1 1.8 7.9 13.4 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Cortex-I_coil PF09304.5 AEO56476.1 - 2.2 8.3 29.2 1.9 8.5 0.2 3.3 1 1 1 3 3 3 0 Cortexillin I, coiled coil Rootletin PF15035.1 AEO56476.1 - 2.3 8.1 30.0 26 4.7 20.9 2.0 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Striatin PF08232.7 AEO56476.1 - 2.4 8.4 27.3 1.2 9.4 11.7 2.3 1 1 1 2 2 2 0 Striatin family CDC37_N PF03234.9 AEO56476.1 - 2.4 8.4 23.0 8 6.7 15.4 2.0 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding Fez1 PF06818.10 AEO56476.1 - 2.5 8.0 28.0 2.9 7.8 19.4 1.1 1 0 0 1 1 1 0 Fez1 DUF1664 PF07889.7 AEO56476.1 - 2.6 7.8 16.2 1.7 8.4 0.7 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Uds1 PF15456.1 AEO56476.1 - 2.9 7.9 26.6 4.8 7.1 4.1 2.7 1 1 1 2 2 2 0 Up-regulated During Septation DUF812 PF05667.6 AEO56476.1 - 3.5 6.0 28.5 1.2 7.6 9.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) TPR_MLP1_2 PF07926.7 AEO56476.1 - 3.8 7.2 35.9 1.7 8.3 11.1 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF3584 PF12128.3 AEO56476.1 - 3.9 4.6 30.2 6 4.0 20.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Ax_dynein_light PF10211.4 AEO56476.1 - 4.1 7.1 32.2 25 4.6 9.2 3.2 1 1 2 3 3 3 0 Axonemal dynein light chain Mnd1 PF03962.10 AEO56476.1 - 5.3 6.6 32.0 7.8 6.1 9.0 2.1 1 1 1 2 2 2 0 Mnd1 family rRNA_proc-arch PF13234.1 AEO56476.1 - 7 5.7 18.8 0.17 11.0 1.9 2.4 1 1 0 2 2 2 0 rRNA-processing arch domain FlxA PF14282.1 AEO56476.1 - 7.6 6.5 23.7 2.4 8.1 10.6 2.7 1 1 0 2 2 2 0 FlxA-like protein DUF4140 PF13600.1 AEO56476.1 - 9.1 6.7 26.8 0.88 10.0 2.9 3.7 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) Nup54 PF13874.1 AEO56476.1 - 9.4 5.8 26.4 3.6 7.2 8.5 2.6 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 DUF2718 PF10918.3 AEO56477.1 - 0.18 11.8 0.5 0.39 10.7 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2718) N-SET PF11764.3 AEO56478.1 - 5.6e-44 149.9 0.4 5.6e-44 149.9 0.3 2.6 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.3 AEO56478.1 - 6.8e-26 89.3 0.5 1.7e-25 88.1 0.4 1.7 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated SET PF00856.23 AEO56478.1 - 8.5e-25 87.9 0.1 8.5e-25 87.9 0.1 4.0 4 1 0 4 4 4 1 SET domain RRM_1 PF00076.17 AEO56478.1 - 0.15 11.7 0.4 14 5.4 0.0 2.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 AEO56478.1 - 0.19 11.5 0.0 0.4 10.5 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif ATP-synt_ab PF00006.20 AEO56479.1 - 1.1e-112 374.7 0.0 1.5e-112 374.2 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 AEO56479.1 - 2.9e-18 66.4 0.5 5e-18 65.6 0.4 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 AEO56479.1 - 1.3e-14 54.1 3.9 3.7e-14 52.6 2.4 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain DUF4048 PF13257.1 AEO56480.1 - 4.9e-10 39.4 44.0 1.7e-09 37.6 15.1 5.1 4 1 1 5 5 5 2 Domain of unknown function (DUF4048) BRCT PF00533.21 AEO56481.1 - 4.2e-05 23.6 0.0 9.4e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Ras PF00071.17 AEO56482.1 - 1.1e-31 109.4 0.3 1.3e-31 109.1 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AEO56482.1 - 7.8e-21 74.7 0.1 3.1e-20 72.8 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 AEO56482.1 - 4e-07 29.4 0.1 5.5e-07 29.0 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 AEO56482.1 - 1.9e-05 23.9 0.3 2.5e-05 23.5 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.6 AEO56482.1 - 0.013 14.1 1.9 0.19 10.3 0.0 2.3 2 1 0 2 2 2 0 Dynein light intermediate chain (DLIC) MMR_HSR1 PF01926.18 AEO56482.1 - 0.065 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.15 AEO56482.1 - 0.07 11.8 0.5 0.21 10.2 0.0 1.8 1 1 1 2 2 2 0 G-protein alpha subunit GCV_H PF01597.14 AEO56483.1 - 9e-35 119.0 1.5 1.1e-34 118.7 1.0 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 AEO56483.1 - 0.0085 15.7 0.4 0.018 14.6 0.3 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme RnfC_N PF13375.1 AEO56483.1 - 0.083 12.6 2.8 0.13 11.9 0.3 2.1 1 1 1 2 2 2 0 RnfC Barrel sandwich hybrid domain Porphobil_deam PF01379.15 AEO56484.1 - 9e-78 260.0 0.0 1.2e-77 259.6 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 AEO56484.1 - 3.4e-18 65.4 0.8 6.7e-18 64.5 0.5 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain TIP120 PF08623.5 AEO56485.1 - 3.5e-68 228.4 2.3 3.3e-65 218.7 0.0 4.1 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 AEO56485.1 - 8.7e-19 67.5 22.2 0.0027 17.9 0.4 9.7 9 2 3 12 12 12 6 HEAT repeats HEAT PF02985.17 AEO56485.1 - 9.1e-13 47.1 19.4 0.11 12.6 0.0 11.2 12 0 0 12 12 12 3 HEAT repeat HEAT_EZ PF13513.1 AEO56485.1 - 6.2e-06 26.5 30.4 0.23 11.9 0.5 11.9 12 2 2 14 14 14 3 HEAT-like repeat Vac14_Fab1_bd PF12755.2 AEO56485.1 - 2.7e-05 24.4 2.3 0.23 11.8 0.0 6.6 5 4 3 8 8 8 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 AEO56485.1 - 0.0021 17.9 6.6 1.9 8.3 0.0 5.6 6 1 0 7 7 7 1 non-SMC mitotic condensation complex subunit 1 VHS PF00790.14 AEO56485.1 - 0.02 14.5 0.0 8.8 5.9 0.0 2.9 2 0 0 2 2 2 0 VHS domain MMS19_C PF12460.3 AEO56485.1 - 0.036 12.7 1.5 23 3.5 0.1 4.6 5 0 0 5 5 5 0 RNAPII transcription regulator C-terminal DUF1930 PF09122.5 AEO56485.1 - 0.066 12.9 0.2 0.25 11.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1930) UME PF08064.8 AEO56485.1 - 0.47 10.4 2.5 21 5.1 0.0 4.2 5 0 0 5 5 5 0 UME (NUC010) domain Prenyltrans_1 PF13243.1 AEO56486.1 - 0.0077 16.2 0.0 0.0077 16.2 0.0 1.1 1 0 0 1 1 1 1 Prenyltransferase-like Prenyltrans_2 PF13249.1 AEO56486.1 - 0.014 15.8 0.0 0.014 15.8 0.0 1.3 1 0 0 1 1 1 0 Prenyltransferase-like Pec_lyase PF09492.5 AEO56486.1 - 0.072 12.2 0.0 0.072 12.2 0.0 1.1 1 0 0 1 1 1 0 Pectic acid lyase Prenyltrans PF00432.16 AEO56487.1 - 1.3e-27 95.0 5.5 2.3e-10 39.8 0.1 5.1 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 AEO56487.1 - 1.3e-21 76.6 0.2 6.8e-12 45.3 0.0 5.8 5 2 1 6 6 6 4 Prenyltransferase-like Prenyltrans_2 PF13249.1 AEO56487.1 - 2.4e-21 76.2 1.1 7.1e-10 39.2 0.0 4.9 4 1 0 4 4 4 3 Prenyltransferase-like Pec_lyase PF09492.5 AEO56487.1 - 4.7e-05 22.7 0.0 1 8.4 0.0 4.0 3 2 1 4 4 4 2 Pectic acid lyase A2M_comp PF07678.9 AEO56487.1 - 0.024 13.8 0.0 6.6 5.8 0.0 3.3 3 1 1 4 4 4 0 A-macroglobulin complement component Chromadorea_ALT PF05535.7 AEO56487.1 - 0.063 13.3 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Chromadorea ALT protein TP6A_N PF04406.9 AEO56488.1 - 2.7e-21 74.9 0.0 7e-21 73.6 0.0 1.7 1 0 0 1 1 1 1 Type IIB DNA topoisomerase DUF2399 PF09664.5 AEO56488.1 - 0.063 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2399) Ank PF00023.25 AEO56489.1 - 1.9e-14 52.6 2.3 7.2e-09 35.0 0.4 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.2 AEO56489.1 - 6.5e-14 52.0 0.1 3.6e-10 40.0 0.0 2.3 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 AEO56489.1 - 3.6e-12 46.1 1.1 3.2e-08 33.5 0.3 3.0 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 AEO56489.1 - 1.4e-11 44.5 2.4 8.2e-06 26.1 0.1 3.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 AEO56489.1 - 1.2e-10 40.5 0.7 3.7e-06 26.6 0.1 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ketoacyl-synt_2 PF13723.1 AEO56489.1 - 0.071 12.3 0.0 0.091 12.0 0.0 1.3 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain Methyltransf_PK PF05891.7 AEO56490.1 - 1e-78 263.6 0.0 1.1e-78 263.4 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.1 AEO56490.1 - 6.8e-06 25.8 0.0 1e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 AEO56490.1 - 0.0041 16.3 0.0 0.0059 15.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 AEO56490.1 - 0.0062 17.0 0.0 0.012 16.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO56490.1 - 0.048 14.1 0.0 0.095 13.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Stm1_N PF09598.5 AEO56491.1 - 0.052 14.2 4.3 0.052 14.2 3.0 2.9 1 1 2 3 3 3 0 Stm1 Gastrin PF00918.12 AEO56491.1 - 2.7 8.8 6.7 0.92 10.3 1.8 1.9 1 1 1 2 2 2 0 Gastrin/cholecystokinin family Lipase_GDSL_2 PF13472.1 AEO56492.1 - 4.7e-17 62.7 2.9 4.7e-17 62.7 2.0 2.1 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 AEO56492.1 - 1.5e-12 47.8 2.3 4.4e-12 46.3 1.6 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase p450 PF00067.17 AEO56493.1 - 1e-47 162.7 0.0 1.3e-47 162.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PLDc_2 PF13091.1 AEO56495.1 - 1.5e-13 50.5 0.0 4.9e-06 26.2 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 AEO56495.1 - 4.8e-08 32.5 1.4 0.012 15.3 0.2 3.2 2 1 0 2 2 2 2 Phospholipase D Active site motif NDUFA12 PF05071.11 AEO56496.1 - 1.2e-24 86.8 2.1 1.5e-24 86.4 1.4 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Crp PF00325.15 AEO56496.1 - 0.12 11.8 0.2 0.2 11.1 0.1 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family PNTB PF02233.11 AEO56497.1 - 1.6e-171 571.1 26.3 1.6e-171 571.1 18.3 1.8 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 AEO56497.1 - 1.3e-54 184.2 0.2 2.3e-54 183.4 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 AEO56497.1 - 3.5e-50 169.5 1.6 8.7e-50 168.2 0.3 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 AEO56497.1 - 2e-31 107.9 3.4 2e-31 107.9 2.4 5.2 5 2 1 6 6 6 1 Domain of unknown function (DUF3814) ADH_zinc_N PF00107.21 AEO56497.1 - 0.0046 16.5 0.1 0.018 14.6 0.1 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.9 AEO56497.1 - 0.0048 16.8 0.2 0.058 13.2 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 AEO56497.1 - 0.0078 15.3 0.5 1.9 7.6 0.0 2.9 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_18 PF12847.2 AEO56497.1 - 0.043 14.3 0.0 0.12 12.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_8 PF13450.1 AEO56497.1 - 7.6 6.6 9.3 0.88 9.6 1.9 2.9 3 1 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Glyco_hydro_61 PF03443.9 AEO56498.1 - 4.1e-48 164.0 0.0 4.6e-48 163.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NPCBM_assoc PF10633.4 AEO56498.1 - 0.061 13.3 0.0 0.15 12.1 0.0 1.7 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase adh_short PF00106.20 AEO56500.1 - 4.2e-08 33.2 0.5 7.4e-08 32.4 0.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO56500.1 - 0.0002 21.0 0.5 0.00033 20.3 0.4 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 AEO56500.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase AA_permease_2 PF13520.1 AEO56501.1 - 9e-81 271.5 27.9 1.1e-80 271.2 19.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 AEO56501.1 - 3.1e-24 85.1 22.3 3.9e-24 84.8 15.5 1.1 1 0 0 1 1 1 1 Amino acid permease Spore_permease PF03845.8 AEO56501.1 - 6.4 5.3 9.2 14 4.2 2.1 3.1 3 0 0 3 3 3 0 Spore germination protein DUF1546 PF07571.8 AEO56504.1 - 8.8e-29 99.4 0.0 2.4e-28 98.0 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 AEO56504.1 - 4.4e-19 68.2 0.0 9.2e-19 67.1 0.0 1.6 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 AEO56504.1 - 0.016 15.2 0.0 0.031 14.3 0.0 1.5 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Sdh_cyt PF01127.17 AEO56505.1 - 3.7e-18 65.5 4.9 4.9e-18 65.1 3.4 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit MFS_1 PF07690.11 AEO56506.1 - 6.7e-32 110.5 42.2 8.8e-30 103.5 18.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO56506.1 - 5e-29 101.1 23.7 4.5e-27 94.7 16.4 2.8 1 1 0 1 1 1 1 Sugar (and other) transporter TPPK_C PF12555.3 AEO56506.1 - 0.86 9.3 4.6 10 5.9 0.0 3.1 3 0 0 3 3 3 0 Thiamine pyrophosphokinase C terminal Pro-kuma_activ PF09286.6 AEO56507.1 - 2.3e-36 124.9 0.0 4.8e-36 123.9 0.0 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 AEO56507.1 - 7.2e-08 31.9 0.0 1.3e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Subtilase family CENP-F_leu_zip PF10473.4 AEO56508.1 - 0.039 13.7 6.0 0.075 12.8 0.9 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.10 AEO56508.1 - 0.095 12.1 9.2 0.52 9.8 4.6 2.3 2 0 0 2 2 2 0 Septum formation initiator ADIP PF11559.3 AEO56508.1 - 0.14 12.0 10.3 1.3 8.8 2.3 2.9 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding TBPIP PF07106.8 AEO56508.1 - 0.35 10.4 6.3 2.9 7.4 1.5 2.3 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) HOOK PF05622.7 AEO56508.1 - 0.55 7.9 8.2 3.2 5.4 0.1 2.3 2 0 0 2 2 2 0 HOOK protein DUF972 PF06156.8 AEO56508.1 - 0.56 10.5 4.7 2.8 8.3 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Spc24 PF08286.6 AEO56508.1 - 0.82 9.3 6.4 2.6 7.7 0.1 2.4 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 APG6 PF04111.7 AEO56508.1 - 2 7.4 8.1 3.3 6.6 1.9 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 IncA PF04156.9 AEO56508.1 - 2.2 7.8 8.5 13 5.3 0.2 2.3 2 0 0 2 2 2 0 IncA protein Prefoldin_2 PF01920.15 AEO56508.1 - 2.4 7.9 9.4 4 7.2 3.9 2.4 2 0 0 2 2 2 0 Prefoldin subunit MerR_2 PF13591.1 AEO56508.1 - 4 7.1 6.7 0.34 10.5 1.0 2.0 2 0 0 2 2 2 0 MerR HTH family regulatory protein DUF3847 PF12958.2 AEO56508.1 - 5.7 6.7 12.3 4.2 7.1 3.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) DUF2802 PF10975.3 AEO56508.1 - 7 6.4 9.1 2.1 8.1 1.8 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2802) RVT_1 PF00078.22 AEO56509.1 - 4.3e-05 22.9 0.7 4.8e-05 22.8 0.5 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DEAD PF00270.24 AEO56510.1 - 4.8e-41 140.0 0.4 1.2e-40 138.7 0.2 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO56510.1 - 4.1e-29 100.2 0.2 9.1e-29 99.1 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 AEO56510.1 - 0.0029 17.3 0.3 0.0067 16.1 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 AEO56510.1 - 0.0064 16.3 0.1 0.019 14.8 0.1 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 AEO56510.1 - 0.0093 15.2 0.5 0.016 14.4 0.1 1.5 2 0 0 2 2 2 1 SecA DEAD-like domain AAA_30 PF13604.1 AEO56510.1 - 0.015 14.8 0.7 0.035 13.6 0.5 1.6 1 1 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.9 AEO56510.1 - 0.035 13.8 0.3 0.12 12.1 0.0 2.0 2 1 0 2 2 2 0 Flavivirus DEAD domain Helicase_RecD PF05127.9 AEO56510.1 - 0.051 13.2 0.0 0.087 12.4 0.0 1.4 1 0 0 1 1 1 0 Helicase AAA_22 PF13401.1 AEO56510.1 - 0.054 13.6 0.5 0.23 11.5 0.3 2.0 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.1 AEO56510.1 - 0.11 12.0 0.2 0.14 11.7 0.2 1.5 1 1 0 1 1 1 0 AAA domain DUF3449 PF11931.3 AEO56511.1 - 1.9e-66 223.3 0.2 1.9e-66 223.3 0.1 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3449) SF3a60_bindingd PF12108.3 AEO56511.1 - 3.6e-12 45.6 0.2 7.5e-12 44.5 0.1 1.6 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-C2H2_jaz PF12171.3 AEO56511.1 - 1.9e-10 40.5 2.0 8.5e-08 32.1 0.2 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 AEO56511.1 - 9.8e-10 38.2 1.0 1.5e-07 31.3 0.3 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 AEO56511.1 - 0.00032 20.7 0.0 0.084 12.9 0.0 2.9 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.7 AEO56511.1 - 0.0051 16.4 0.1 0.0051 16.4 0.1 2.5 2 1 0 2 2 2 1 DBF zinc finger zf-C2H2_4 PF13894.1 AEO56511.1 - 0.09 13.1 3.8 5.8 7.4 0.3 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 AEO56511.1 - 1.2 9.6 3.2 38 4.8 0.2 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type GIY-YIG PF01541.19 AEO56512.1 - 3.6e-07 30.4 0.0 6.4e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain zf-RING_2 PF13639.1 AEO56512.1 - 0.0069 16.2 3.8 0.011 15.5 2.6 1.4 1 0 0 1 1 1 1 Ring finger domain PHD PF00628.24 AEO56512.1 - 0.017 14.8 3.3 0.025 14.2 2.3 1.3 1 0 0 1 1 1 0 PHD-finger T5orf172 PF10544.4 AEO56512.1 - 0.035 14.5 0.1 0.13 12.6 0.0 2.0 2 0 0 2 2 2 0 T5orf172 domain zf-HC5HC2H PF13771.1 AEO56512.1 - 0.051 13.7 0.6 0.09 12.9 0.4 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 AEO56512.1 - 0.09 12.7 0.8 0.15 12.0 0.5 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain FANCL_C PF11793.3 AEO56512.1 - 0.12 12.3 1.8 0.2 11.6 1.3 1.3 1 0 0 1 1 1 0 FANCL C-terminal domain PLU-1 PF08429.6 AEO56513.1 - 7.3e-111 370.2 11.0 2.9e-108 361.7 6.9 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.17 AEO56513.1 - 1.1e-43 148.0 0.2 3.2e-43 146.5 0.1 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.16 AEO56513.1 - 1.9e-27 94.9 0.1 6.1e-27 93.3 0.1 2.0 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.24 AEO56513.1 - 1.8e-17 62.7 30.1 1.3e-09 37.5 4.3 3.7 3 0 0 3 3 3 2 PHD-finger JmjN PF02375.12 AEO56513.1 - 6.8e-15 54.3 1.4 1.5e-14 53.1 1.0 1.6 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.11 AEO56513.1 - 1.6e-14 53.6 5.9 4.6e-14 52.2 4.1 1.8 1 0 0 1 1 1 1 C5HC2 zinc finger Chloroplast_duf PF14476.1 AEO56513.1 - 0.015 14.0 2.0 0.058 12.1 0.0 2.2 2 0 0 2 2 2 0 Petal formation-expressed C1_1 PF00130.17 AEO56513.1 - 0.25 11.0 17.3 0.13 12.0 0.5 2.9 3 0 0 3 3 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Rubredoxin PF00301.15 AEO56513.1 - 0.92 9.4 15.3 0.021 14.6 1.6 3.3 2 1 0 2 2 2 0 Rubredoxin PHD_2 PF13831.1 AEO56513.1 - 1.4 8.2 11.5 0.085 12.1 0.8 2.8 2 0 0 2 2 2 0 PHD-finger Prok-RING_1 PF14446.1 AEO56513.1 - 2.5 7.8 15.2 0.042 13.5 0.6 3.3 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 DUF1688 PF07958.6 AEO56514.1 - 8.3e-175 581.3 0.0 9.8e-175 581.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) NESP55 PF06390.7 AEO56515.1 - 0.24 10.7 4.0 0.55 9.5 2.7 1.5 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) RPW8 PF05659.6 AEO56516.1 - 0.2 11.1 0.0 0.33 10.4 0.0 1.2 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Bys1 PF04681.7 AEO56517.1 - 2.3e-12 46.9 0.0 2.6e-12 46.7 0.0 1.0 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein HET PF06985.6 AEO56518.1 - 1.7e-29 102.7 0.0 2.1e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NOB1_Zn_bind PF08772.6 AEO56519.1 - 2.6e-31 107.2 4.0 5e-31 106.3 2.8 1.5 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like AF1Q PF15017.1 AEO56519.1 - 4.2e-05 23.3 1.9 4.2e-05 23.3 1.3 2.0 2 0 0 2 2 2 1 Drug resistance and apoptosis regulator zf-NADH-PPase PF09297.6 AEO56519.1 - 0.48 9.9 6.6 0.061 12.8 0.7 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Nop10p PF04135.7 AEO56520.1 - 1.2e-17 63.3 0.1 1.5e-17 63.0 0.1 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family DUF3627 PF12299.3 AEO56520.1 - 0.15 12.1 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3627) zf-Di19 PF05605.7 AEO56522.1 - 0.019 15.0 0.1 0.043 13.9 0.1 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.1 AEO56522.1 - 0.024 14.8 1.1 0.89 9.9 0.2 2.8 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.1 AEO56522.1 - 0.047 14.0 1.7 0.047 14.0 1.2 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 AEO56522.1 - 0.51 10.4 2.6 0.51 10.4 0.3 1.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.1 AEO56522.1 - 4.4 7.7 9.9 15 6.1 0.4 3.5 3 0 0 3 3 3 0 Zinc-finger double domain Fig1 PF12351.3 AEO56523.1 - 3.8e-22 79.0 0.1 1.1e-21 77.5 0.0 1.7 1 1 1 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 AEO56523.1 - 8.9e-05 22.1 0.0 0.00016 21.3 0.0 1.4 1 1 0 1 1 1 1 SUR7/PalI family MFS_1 PF07690.11 AEO56524.1 - 2.8e-26 92.1 22.3 2.8e-26 92.1 15.5 2.8 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.11 AEO56525.1 - 4.1e-39 134.2 50.3 1.4e-38 132.5 34.8 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 AEO56525.1 - 8.3e-13 47.3 23.5 9.8e-13 47.1 15.5 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) B3_4 PF03483.12 AEO56526.1 - 1.6e-26 92.7 0.1 2.9e-26 91.9 0.1 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 AEO56526.1 - 1.9e-16 59.6 0.0 8.2e-15 54.3 0.0 2.6 2 0 0 2 2 2 1 tRNA synthetase B5 domain Hap4_Hap_bind PF10297.4 AEO56528.1 - 2.4e-09 36.7 7.1 6.6e-09 35.3 4.9 1.9 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.16 AEO56528.1 - 2.3e-06 27.4 11.3 1.5e-05 24.8 1.8 2.4 2 0 0 2 2 2 2 bZIP transcription factor CASP_C PF08172.7 AEO56528.1 - 0.002 17.1 1.6 0.0048 15.9 1.1 1.6 1 0 0 1 1 1 1 CASP C terminal Tropomyosin_1 PF12718.2 AEO56528.1 - 0.017 14.9 2.8 0.03 14.1 2.0 1.4 1 0 0 1 1 1 0 Tropomyosin like Spc24 PF08286.6 AEO56528.1 - 0.1 12.2 1.1 0.17 11.6 0.7 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 IncA PF04156.9 AEO56528.1 - 0.16 11.5 5.7 0.27 10.8 3.9 1.3 1 0 0 1 1 1 0 IncA protein Striatin PF08232.7 AEO56528.1 - 0.2 11.9 4.9 0.44 10.8 3.4 1.6 1 0 0 1 1 1 0 Striatin family TMF_DNA_bd PF12329.3 AEO56528.1 - 0.2 11.4 1.8 0.37 10.6 1.2 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding bZIP_Maf PF03131.12 AEO56528.1 - 0.36 11.1 8.3 0.67 10.2 5.7 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor Cortex-I_coil PF09304.5 AEO56528.1 - 0.59 10.2 5.0 1.1 9.3 3.5 1.3 1 0 0 1 1 1 0 Cortexillin I, coiled coil bZIP_2 PF07716.10 AEO56528.1 - 2.2 8.1 13.5 8.6 6.2 5.1 2.3 1 1 1 2 2 2 0 Basic region leucine zipper Ribosomal_L1 PF00687.16 AEO56529.1 - 1.8e-23 83.0 0.0 2.2e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family zf-XS PF03470.9 AEO56529.1 - 0.092 12.8 0.3 0.17 11.9 0.2 1.4 1 0 0 1 1 1 0 XS zinc finger domain tRNA-synt_1c PF00749.16 AEO56530.1 - 1.1e-101 339.6 0.2 1.4e-101 339.2 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 AEO56530.1 - 2.2e-42 144.7 0.0 3.6e-42 143.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 AEO56530.1 - 0.00024 21.5 0.0 0.00068 20.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.14 AEO56530.1 - 0.0015 17.7 0.5 0.0042 16.2 0.4 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain FCD PF07729.7 AEO56530.1 - 1.3 9.3 5.3 3 8.1 0.1 2.7 3 0 0 3 3 3 0 FCD domain Choline_transpo PF04515.7 AEO56531.1 - 8.6e-103 343.5 15.8 8.6e-103 343.5 11.0 2.1 2 0 0 2 2 2 1 Plasma-membrane choline transporter IspA PF04279.10 AEO56531.1 - 1 9.2 18.4 0.073 13.0 7.3 2.7 2 2 0 2 2 2 0 Intracellular septation protein A DrsE PF02635.10 AEO56532.1 - 0.09 12.8 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 DsrE/DsrF-like family DUF3431 PF11913.3 AEO56533.1 - 5.4e-59 199.3 0.1 1.2e-58 198.1 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3431) P12 PF12669.2 AEO56534.1 - 0.19 11.9 0.0 0.19 11.9 0.0 2.6 3 0 0 3 3 3 0 Virus attachment protein p12 family Zip PF02535.17 AEO56535.1 - 0.42 9.5 1.4 0.65 8.9 1.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF202 PF02656.10 AEO56536.1 - 0.075 13.2 1.5 2.5 8.3 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Rrp15p PF07890.7 AEO56539.1 - 3.3e-35 120.9 8.9 3.3e-35 120.9 6.2 1.9 2 0 0 2 2 2 1 Rrp15p TFIIF_beta PF02270.10 AEO56539.1 - 1.3 8.7 5.0 0.5 10.1 1.5 1.7 1 1 1 2 2 2 0 Transcription initiation factor IIF, beta subunit Fer2 PF00111.22 AEO56540.1 - 1.6e-13 50.2 0.7 2.4e-13 49.6 0.5 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Mito_carr PF00153.22 AEO56541.1 - 3.9e-18 64.9 0.0 3.9e-05 23.2 0.1 5.3 5 1 0 5 5 5 4 Mitochondrial carrier protein Ribosomal_60s PF00428.14 AEO56541.1 - 0.051 13.9 0.3 0.051 13.9 0.2 2.7 3 0 0 3 3 3 0 60s Acidic ribosomal protein Glyco_hydro_61 PF03443.9 AEO56542.1 - 3e-81 272.3 1.1 3.1e-81 272.3 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 AEO56542.1 - 9.6e-14 50.7 9.5 2.4e-13 49.4 6.6 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain CSD PF00313.17 AEO56542.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain BA14K PF07886.6 AEO56542.1 - 1.2 8.9 4.1 2.2 8.0 2.8 1.4 1 0 0 1 1 1 0 BA14K-like protein adh_short PF00106.20 AEO56544.1 - 2.6e-13 50.2 2.4 5.1e-13 49.2 1.7 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO56544.1 - 8.3e-05 22.3 2.3 0.00026 20.6 1.4 1.9 1 1 1 2 2 2 1 KR domain Mfp-3 PF04202.8 AEO56544.1 - 0.017 15.3 0.2 0.29 11.3 0.0 2.3 2 0 0 2 2 2 0 Foot protein 3 NAD_binding_8 PF13450.1 AEO56545.1 - 1.1e-10 41.4 0.1 3.3e-10 39.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 AEO56545.1 - 1.6e-07 30.5 0.5 2.7e-07 29.8 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 AEO56545.1 - 5.3e-07 28.8 0.6 1e-06 27.9 0.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 AEO56545.1 - 5.9e-06 25.6 0.4 1e-05 24.8 0.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 AEO56545.1 - 2e-05 23.2 0.3 3.1e-05 22.6 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 AEO56545.1 - 7.3e-05 22.9 0.0 0.00022 21.3 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AEO56545.1 - 0.00016 21.9 0.2 0.00033 21.0 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 AEO56545.1 - 0.00037 20.4 0.0 0.00062 19.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 AEO56545.1 - 0.001 18.2 0.4 0.0017 17.4 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 AEO56545.1 - 0.0012 18.0 0.6 0.0025 16.9 0.4 1.5 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 AEO56545.1 - 0.0082 15.0 0.2 0.012 14.4 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A IlvN PF07991.7 AEO56545.1 - 0.013 14.8 0.2 0.026 13.8 0.1 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Amino_oxidase PF01593.19 AEO56545.1 - 0.043 12.8 0.0 0.056 12.5 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 AEO56545.1 - 0.059 12.2 0.0 0.086 11.7 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein 3HCDH_N PF02737.13 AEO56545.1 - 0.085 12.5 0.7 0.14 11.7 0.5 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Gate PF07670.9 AEO56546.1 - 0.073 12.9 1.1 6 6.8 0.0 2.4 2 0 0 2 2 2 0 Nucleoside recognition Glyco_hydro_61 PF03443.9 AEO56547.1 - 2.4e-47 161.5 0.0 2.8e-47 161.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Gly_transf_sug PF04488.10 AEO56548.1 - 6.2e-15 55.4 0.1 9.6e-15 54.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 AEO56548.1 - 0.14 10.6 1.1 0.98 7.8 0.4 2.0 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Voldacs PF03517.8 AEO56549.1 - 4.3e-20 71.9 0.0 7.3e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Fringe PF02434.11 AEO56549.1 - 1.2e-05 24.7 0.0 2.7e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.16 AEO56549.1 - 0.034 13.7 0.0 0.08 12.5 0.0 1.6 1 1 0 1 1 1 0 Galactosyltransferase Pol_alpha_B_N PF08418.5 AEO56551.1 - 1.5e-60 204.8 0.0 2e-60 204.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 AEO56551.1 - 5.6e-43 146.6 0.0 7.6e-43 146.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B CRAL_TRIO PF00650.15 AEO56552.1 - 2.7e-40 137.4 0.0 4.4e-40 136.7 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 AEO56552.1 - 1.4e-09 37.8 0.3 3.5e-09 36.6 0.2 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 AEO56552.1 - 0.0003 20.7 0.0 0.00043 20.2 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain E1-E2_ATPase PF00122.15 AEO56553.1 - 1.3e-19 70.2 0.0 3.1e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 AEO56553.1 - 3.8e-18 66.6 0.0 6.4e-17 62.6 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 AEO56553.1 - 7.6e-14 52.3 0.0 7.2e-13 49.1 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AEO56553.1 - 1.6e-12 47.1 0.0 5.5e-12 45.4 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 AEO56553.1 - 0.003 17.1 0.0 0.011 15.3 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase UBX PF00789.15 AEO56553.1 - 0.059 13.4 0.1 18 5.5 0.1 2.6 2 0 0 2 2 2 0 UBX domain HAD_2 PF13419.1 AEO56553.1 - 0.073 13.2 0.9 0.12 12.6 0.0 1.8 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Homeobox PF00046.24 AEO56554.1 - 7.1e-20 70.3 4.8 1.4e-19 69.4 3.3 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 AEO56554.1 - 0.00023 20.8 0.7 0.00064 19.3 0.5 1.8 1 0 0 1 1 1 1 Homeobox KN domain Adaptin_binding PF10199.4 AEO56555.1 - 1.8e-13 50.9 2.3 1.8e-13 50.9 1.6 2.5 2 1 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 Fungal_trans PF04082.13 AEO56556.1 - 2.3e-20 72.5 0.0 3e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO56556.1 - 1e-05 25.3 6.8 2.2e-05 24.2 4.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aconitase PF00330.15 AEO56557.1 - 1.1e-70 238.4 0.0 2.8e-43 148.0 0.0 2.1 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 AEO56557.1 - 1.6e-24 86.4 0.0 3.2e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain IPPT PF01715.12 AEO56558.1 - 9.2e-52 175.5 0.0 1.6e-51 174.7 0.0 1.4 1 0 0 1 1 1 1 IPP transferase AAA_17 PF13207.1 AEO56558.1 - 8.4e-06 26.6 0.5 2.9e-05 24.8 0.3 2.2 1 1 0 1 1 1 1 AAA domain zf-C2H2_jaz PF12171.3 AEO56558.1 - 1.4e-05 25.0 0.2 1.4e-05 25.0 0.1 1.7 2 0 0 2 2 1 1 Zinc-finger double-stranded RNA-binding IPT PF01745.11 AEO56558.1 - 1.9e-05 23.9 0.0 8.4e-05 21.8 0.0 1.9 2 0 0 2 2 2 1 Isopentenyl transferase zf-met PF12874.2 AEO56558.1 - 5e-05 23.3 0.2 9.8e-05 22.4 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type AAA_22 PF13401.1 AEO56558.1 - 0.0024 17.9 0.0 0.006 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AEO56558.1 - 0.0038 17.5 0.2 0.12 12.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain PSCyt3 PF07627.6 AEO56558.1 - 0.005 16.6 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1588) AAA_33 PF13671.1 AEO56558.1 - 0.013 15.4 0.3 0.36 10.7 0.0 2.8 3 1 0 3 3 3 0 AAA domain Arch_ATPase PF01637.13 AEO56558.1 - 0.018 14.7 0.0 0.036 13.7 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase AAA_28 PF13521.1 AEO56558.1 - 0.041 13.8 0.1 0.36 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 AEO56558.1 - 0.044 13.9 0.0 0.096 12.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Hpr_kinase_C PF07475.7 AEO56558.1 - 0.052 12.8 0.0 0.095 12.0 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain ABC_tran PF00005.22 AEO56558.1 - 0.06 13.6 0.1 0.35 11.1 0.0 2.2 3 0 0 3 3 3 0 ABC transporter AAA_25 PF13481.1 AEO56558.1 - 0.065 12.6 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 AEO56558.1 - 0.11 12.6 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SecY PF00344.15 AEO56559.1 - 2e-96 322.9 10.7 2.5e-96 322.6 7.4 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 AEO56559.1 - 5.4e-18 64.2 0.4 3.6e-17 61.5 0.2 2.4 2 0 0 2 2 2 1 Plug domain of Sec61p RseC_MucC PF04246.7 AEO56559.1 - 2 7.9 4.4 0.79 9.2 0.0 2.4 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC ABC_tran PF00005.22 AEO56560.1 - 7.9e-53 178.4 0.0 1.1e-30 106.7 0.0 3.1 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 AEO56560.1 - 2.1e-40 138.8 19.5 5.2e-21 75.2 4.8 3.5 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.14 AEO56560.1 - 6.6e-09 35.3 2.6 0.0031 16.7 0.4 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 AEO56560.1 - 1.3e-08 35.4 0.0 3.5e-05 24.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 AEO56560.1 - 5.2e-08 33.1 0.2 0.076 12.9 0.0 3.5 3 0 0 3 3 3 2 AAA domain T2SE PF00437.15 AEO56560.1 - 6.9e-06 25.1 0.1 0.013 14.4 0.1 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.1 AEO56560.1 - 1.1e-05 24.8 0.5 0.086 12.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 AEO56560.1 - 2.8e-05 23.6 0.0 0.31 10.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 AEO56560.1 - 0.00011 22.2 4.2 0.099 12.6 1.3 3.2 2 1 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 AEO56560.1 - 0.00057 19.1 0.0 0.9 8.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 AEO56560.1 - 0.00067 19.1 0.0 1.6 8.0 0.0 3.1 3 0 0 3 3 3 2 AAA-like domain IstB_IS21 PF01695.12 AEO56560.1 - 0.0016 17.8 0.0 0.68 9.3 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein MobB PF03205.9 AEO56560.1 - 0.0018 17.9 0.7 11 5.6 0.1 3.5 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 AEO56560.1 - 0.002 17.2 0.7 1.6 7.8 0.1 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_22 PF13401.1 AEO56560.1 - 0.0027 17.8 0.6 3.3 7.8 0.0 3.6 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.18 AEO56560.1 - 0.0031 17.4 0.1 0.23 11.4 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF87 PF01935.12 AEO56560.1 - 0.0034 17.2 1.1 0.16 11.7 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 Miro PF08477.8 AEO56560.1 - 0.0045 17.4 0.3 5.5 7.5 0.1 2.9 2 0 0 2 2 2 1 Miro-like protein AAA_17 PF13207.1 AEO56560.1 - 0.0055 17.5 0.0 3.7 8.3 0.0 3.0 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 AEO56560.1 - 0.0098 15.3 0.1 4.7 6.6 0.1 2.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family ResIII PF04851.10 AEO56560.1 - 0.032 14.0 0.1 9.3 6.0 0.1 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_18 PF13238.1 AEO56560.1 - 0.055 13.7 0.7 4 7.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 AEO56560.1 - 0.09 12.4 0.0 0.77 9.4 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase RNA_helicase PF00910.17 AEO56560.1 - 0.14 12.3 0.3 20 5.4 0.0 3.0 3 0 0 3 3 2 0 RNA helicase NB-ARC PF00931.17 AEO56560.1 - 0.23 10.2 0.2 1.1 8.0 0.0 2.1 3 0 0 3 3 3 0 NB-ARC domain Pox_A32 PF04665.7 AEO56560.1 - 0.37 10.0 0.3 7.4 5.7 0.1 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein cobW PF02492.14 AEO56560.1 - 0.7 9.3 3.1 1.3 8.3 0.3 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TRAP_alpha PF03896.11 AEO56561.1 - 0.15 11.0 0.9 0.19 10.7 0.6 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Troponin-I_N PF11636.3 AEO56561.1 - 0.65 9.7 2.8 0.84 9.3 1.9 1.2 1 0 0 1 1 1 0 Troponin I residues 1-32 HemY_N PF07219.8 AEO56561.1 - 2.2 7.8 5.7 0.39 10.2 0.8 1.9 1 1 1 2 2 2 0 HemY protein N-terminus DUF1183 PF06682.7 AEO56562.1 - 0.0072 15.9 0.1 0.0095 15.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) DUF1180 PF06679.7 AEO56562.1 - 0.017 14.9 2.2 0.043 13.7 1.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) Serglycin PF04360.7 AEO56562.1 - 0.48 10.1 5.2 0.071 12.8 0.9 1.6 1 1 0 2 2 2 0 Serglycin A1_Propeptide PF07966.7 AEO56564.1 - 0.1 12.4 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 A1 Propeptide Apc13p PF05839.6 AEO56567.1 - 7.8e-38 128.3 0.1 8.7e-38 128.1 0.1 1.0 1 0 0 1 1 1 1 Apc13p protein TRAPP PF04051.11 AEO56568.1 - 2.9e-37 127.5 0.0 3.4e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component SGS PF05002.10 AEO56569.1 - 1.3e-27 95.3 2.0 1.3e-27 95.3 1.4 1.9 2 0 0 2 2 2 1 SGS domain CS PF04969.11 AEO56569.1 - 1.4e-14 54.3 0.0 2.3e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 CS domain TPR_11 PF13414.1 AEO56569.1 - 1.4e-08 34.2 2.9 5.5e-07 29.1 0.2 2.5 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 AEO56569.1 - 4e-07 29.4 3.2 0.18 11.7 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 AEO56569.1 - 4.9e-06 25.9 0.5 0.27 10.9 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 AEO56569.1 - 6.9e-06 26.5 9.2 4.9e-05 23.8 2.8 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 AEO56569.1 - 0.00045 20.5 5.1 0.002 18.4 1.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 AEO56569.1 - 0.0031 17.1 1.2 3.3 7.6 0.0 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 AEO56569.1 - 0.0043 17.1 1.0 0.011 15.8 0.7 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 AEO56569.1 - 0.04 13.7 2.2 28 4.8 0.4 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 AEO56569.1 - 0.12 12.2 4.0 1.9 8.4 2.5 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 AEO56569.1 - 0.61 10.8 6.6 17 6.4 0.2 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 AEO56569.1 - 1.1 9.1 5.0 0.82 9.5 0.8 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat Glyco_transf_21 PF13506.1 AEO56570.1 - 5.5e-10 38.7 0.0 0.00014 21.1 0.0 3.6 3 1 0 3 3 3 3 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 AEO56570.1 - 1.4e-07 31.5 0.0 4.2e-07 29.9 0.0 1.9 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 AEO56570.1 - 0.12 12.0 0.0 0.32 10.6 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferase family 2 tRNA_int_endo PF01974.12 AEO56571.1 - 8.3e-21 73.5 0.0 1.5e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 AEO56571.1 - 2.1e-07 30.3 0.0 0.0016 17.9 0.0 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain ABC_tran PF00005.22 AEO56572.1 - 9.7e-20 71.2 0.0 1.8e-19 70.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 AEO56572.1 - 3.3e-06 27.2 0.0 0.064 13.2 0.0 2.1 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 AEO56572.1 - 2.2e-05 23.7 0.2 0.016 14.4 0.1 2.6 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 AEO56572.1 - 0.0062 16.0 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Miro PF08477.8 AEO56572.1 - 0.0078 16.7 0.0 0.014 15.8 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein AAA_22 PF13401.1 AEO56572.1 - 0.024 14.7 0.0 0.19 11.8 0.0 2.1 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 AEO56572.1 - 0.03 14.2 0.0 0.096 12.6 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_25 PF13481.1 AEO56572.1 - 0.043 13.2 0.7 0.2 11.0 0.1 2.1 2 1 0 2 2 2 0 AAA domain DUF258 PF03193.11 AEO56572.1 - 0.046 12.9 0.0 0.072 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 AEO56572.1 - 0.055 12.9 0.0 0.097 12.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.1 AEO56572.1 - 0.14 12.1 2.3 0.44 10.5 1.6 1.9 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 AEO56573.1 - 3.8e-19 69.3 0.0 7.5e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 AEO56573.1 - 8.1e-18 64.7 17.3 9e-12 44.9 3.9 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 AEO56573.1 - 0.00076 19.5 0.0 0.85 9.5 0.0 2.3 1 1 1 2 2 2 2 AAA domain T2SE PF00437.15 AEO56573.1 - 0.0059 15.5 0.0 0.01 14.7 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein SMC_N PF02463.14 AEO56573.1 - 0.012 14.9 0.1 1.2 8.3 0.0 2.1 1 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_33 PF13671.1 AEO56573.1 - 0.029 14.2 0.0 0.058 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 AEO56573.1 - 0.11 13.3 0.0 0.23 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 AEO56573.1 - 0.15 11.7 0.1 0.43 10.2 0.1 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 AEO56573.1 - 0.18 11.6 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Dynamin family PS_Dcarbxylase PF02666.10 AEO56574.1 - 2.5e-15 56.3 0.8 1.2e-07 31.2 0.1 2.1 1 1 1 2 2 2 2 Phosphatidylserine decarboxylase Fungal_trans PF04082.13 AEO56575.1 - 3.5e-52 176.8 0.1 4.8e-52 176.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain ImpA-rel_N PF06812.7 AEO56575.1 - 0.042 13.6 0.1 0.32 10.8 0.0 2.3 2 0 0 2 2 2 0 ImpA-related N-terminal APH PF01636.18 AEO56576.1 - 8.7e-18 64.9 8.3 8.7e-18 64.9 5.8 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 AEO56576.1 - 0.011 15.2 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase EcKinase PF02958.15 AEO56576.1 - 0.056 12.5 0.0 0.12 11.5 0.0 1.4 2 0 0 2 2 2 0 Ecdysteroid kinase DUF3240 PF11582.3 AEO56576.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3240) DUF1679 PF07914.6 AEO56576.1 - 0.15 10.6 0.0 0.22 10.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) GFA PF04828.9 AEO56577.1 - 1.6e-19 69.6 0.6 2.4e-19 69.0 0.4 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.6 AEO56577.1 - 1.6 8.6 4.7 3.5 7.5 0.2 2.3 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Cys_rich_CWC PF14375.1 AEO56577.1 - 2.4 8.1 7.7 0.21 11.5 0.8 2.1 2 0 0 2 2 2 0 Cysteine-rich CWC FAD_binding_4 PF01565.18 AEO56579.1 - 6e-19 67.8 1.0 1.2e-18 66.9 0.7 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 AEO56579.1 - 5.3e-13 48.6 0.6 1.2e-12 47.5 0.4 1.6 1 0 0 1 1 1 1 Berberine and berberine like DUF605 PF04652.11 AEO56580.1 - 2.4 7.4 22.0 3.7 6.8 15.2 1.3 1 0 0 1 1 1 0 Vta1 like DUF1183 PF06682.7 AEO56580.1 - 5.4 6.5 14.0 41 3.6 7.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1183) DEAD PF00270.24 AEO56583.1 - 3.4e-37 127.5 0.0 6.4e-37 126.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO56583.1 - 3.2e-21 74.9 0.0 8.4e-20 70.4 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AEO56583.1 - 0.00025 20.9 0.0 0.00046 20.0 0.0 1.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 AEO56583.1 - 0.02 14.4 0.0 0.051 13.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain SecA_DEAD PF07517.9 AEO56583.1 - 0.038 13.2 0.0 0.16 11.2 0.0 1.8 2 0 0 2 2 2 0 SecA DEAD-like domain AAA_24 PF13479.1 AEO56583.1 - 0.22 11.1 0.0 23 4.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain adh_short PF00106.20 AEO56585.1 - 7.5e-07 29.2 0.7 1.4e-06 28.3 0.5 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO56585.1 - 0.0019 17.8 0.7 0.0063 16.2 0.5 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 AEO56585.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pkinase PF00069.20 AEO56586.1 - 3.6e-24 85.3 0.1 1.4e-20 73.5 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AEO56586.1 - 1.9e-18 66.5 0.2 7.2e-15 54.7 0.1 3.6 1 1 1 2 2 2 2 Protein tyrosine kinase DUF825 PF05695.7 AEO56586.1 - 0.002 15.6 0.1 0.0025 15.3 0.1 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF825) P53 PF00870.13 AEO56586.1 - 0.025 14.1 0.0 0.042 13.4 0.0 1.2 1 0 0 1 1 1 0 P53 DNA-binding domain SMP PF04927.7 AEO56587.1 - 0.00039 20.3 0.4 0.042 13.8 0.0 2.1 1 1 1 2 2 2 2 Seed maturation protein Con-6 PF10346.4 AEO56588.1 - 1.5e-31 107.4 4.1 1.5e-15 56.2 0.6 2.2 2 0 0 2 2 2 2 Conidiation protein 6 Toxin_52 PF15605.1 AEO56588.1 - 0.0077 16.1 0.3 0.92 9.4 0.0 2.1 2 0 0 2 2 2 2 Putative toxin 52 YqeY PF09424.5 AEO56588.1 - 0.11 12.3 0.9 0.16 11.7 0.1 1.6 2 0 0 2 2 2 0 Yqey-like protein DNase_NucA_NucB PF14040.1 AEO56589.1 - 0.00022 21.3 1.8 0.019 15.1 0.1 2.7 2 1 0 3 3 3 2 Deoxyribonuclease NucA/NucB Chitin_bind_1 PF00187.14 AEO56591.1 - 0.18 11.8 34.3 0.29 11.1 14.0 2.7 2 1 1 3 3 3 0 Chitin recognition protein Erythro_esteras PF05139.9 AEO56592.1 - 1.5e-144 481.4 1.1 1.9e-144 481.1 0.8 1.1 1 0 0 1 1 1 1 Erythromycin esterase Zn_clus PF00172.13 AEO56594.1 - 0.024 14.5 12.4 0.054 13.4 8.6 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain RAP1 PF07218.6 AEO56594.1 - 5.3 5.0 6.2 7.3 4.5 4.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Ank_2 PF12796.2 AEO56595.1 - 6e-55 183.5 23.1 2.5e-14 53.3 0.0 11.6 6 3 3 10 10 10 10 Ankyrin repeats (3 copies) Ank PF00023.25 AEO56595.1 - 1.1e-35 119.6 24.7 7.3e-05 22.3 0.0 15.2 16 0 0 16 16 16 10 Ankyrin repeat Ank_4 PF13637.1 AEO56595.1 - 2.4e-27 94.8 20.5 4.1e-08 33.5 0.0 13.0 11 4 3 14 14 14 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 AEO56595.1 - 1.8e-26 89.5 21.8 0.00029 20.7 0.0 16.6 19 1 1 20 20 20 4 Ankyrin repeat Ank_5 PF13857.1 AEO56595.1 - 2.4e-16 59.3 15.2 3.4e-06 27.1 0.0 9.8 9 1 2 11 11 11 4 Ankyrin repeats (many copies) CAP_N PF01213.14 AEO56596.1 - 2.2 7.5 7.2 3.8 6.6 5.0 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal APH PF01636.18 AEO56597.1 - 8.5e-12 45.3 0.5 1.4e-10 41.2 0.4 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 AEO56597.1 - 0.0068 15.0 0.0 0.0095 14.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) QLQ PF08880.6 AEO56597.1 - 0.04 13.3 0.0 0.086 12.2 0.0 1.6 1 0 0 1 1 1 0 QLQ MFS_1 PF07690.11 AEO56598.1 - 3.5e-40 137.7 48.6 1.8e-39 135.4 33.7 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO56598.1 - 6.8e-13 48.0 29.9 2e-12 46.4 11.7 2.8 3 0 0 3 3 3 2 Sugar (and other) transporter Arylsulfotran_2 PF14269.1 AEO56599.1 - 3.8e-72 242.9 0.9 5.7e-72 242.3 0.6 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 AEO56599.1 - 1.7e-16 59.8 0.2 3e-15 55.7 0.1 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Peptidase_M14 PF00246.19 AEO56600.1 - 1.3e-76 257.8 0.0 1.8e-76 257.4 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.11 AEO56600.1 - 1.7e-06 27.6 0.0 1.7e-05 24.4 0.0 2.5 3 0 0 3 3 3 1 Carboxypeptidase activation peptide Gtr1_RagA PF04670.7 AEO56602.1 - 2.8e-97 324.4 0.9 4.9e-96 320.3 0.7 2.0 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 AEO56602.1 - 2.3e-09 36.7 0.1 3.7e-09 36.0 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 AEO56602.1 - 3.8e-08 32.8 0.1 5.9e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 AEO56602.1 - 3.7e-06 26.8 0.0 7.3e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 AEO56602.1 - 5.2e-05 23.7 0.2 0.00012 22.5 0.0 1.8 2 0 0 2 2 1 1 Miro-like protein AAA_29 PF13555.1 AEO56602.1 - 0.0015 17.9 0.5 0.011 15.2 0.1 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF815 PF05673.8 AEO56602.1 - 0.0092 14.9 0.1 0.02 13.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) DUF258 PF03193.11 AEO56602.1 - 0.012 14.8 0.0 0.021 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 INTS5_N PF14837.1 AEO56602.1 - 0.023 14.1 0.2 0.038 13.3 0.2 1.4 1 0 0 1 1 1 0 Integrator complex subunit 5 N-terminus Spt20 PF12090.3 AEO56602.1 - 0.028 13.7 0.2 0.038 13.3 0.1 1.2 1 0 0 1 1 1 0 Spt20 family G-alpha PF00503.15 AEO56602.1 - 0.031 12.9 3.5 0.45 9.1 0.0 3.1 3 0 0 3 3 3 0 G-protein alpha subunit ABC_tran PF00005.22 AEO56602.1 - 0.091 13.0 4.5 0.29 11.4 3.2 1.9 1 1 0 1 1 1 0 ABC transporter SEP PF08059.8 AEO56603.1 - 3.6e-26 91.2 0.0 6.8e-26 90.3 0.0 1.5 1 0 0 1 1 1 1 SEP domain UBA_4 PF14555.1 AEO56603.1 - 4.4e-12 45.3 0.1 7.3e-12 44.6 0.1 1.4 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 AEO56603.1 - 3.8e-10 39.6 0.0 6.8e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 UBX domain Lipoprotein_19 PF13617.1 AEO56603.1 - 0.17 11.5 0.1 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 YnbE-like lipoprotein 60KD_IMP PF02096.15 AEO56604.1 - 6.1e-32 110.8 5.5 9.4e-32 110.2 3.8 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein TOM13 PF08219.6 AEO56604.1 - 2e-29 101.1 0.0 5.3e-29 99.8 0.0 1.7 1 0 0 1 1 1 1 Outer membrane protein TOM13 Pro_CA PF00484.14 AEO56605.1 - 3.7e-27 95.1 0.0 4.7e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Ank_2 PF12796.2 AEO56607.1 - 3.8e-14 52.7 0.0 1.1e-12 48.1 0.0 2.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 AEO56607.1 - 5e-14 51.3 3.5 2.8e-05 23.6 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 AEO56607.1 - 4.9e-10 38.6 1.5 0.0026 17.8 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 AEO56607.1 - 6.4e-09 36.0 1.2 7.2e-06 26.3 0.3 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 AEO56607.1 - 1.1e-08 35.0 1.3 0.0062 16.7 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 AEO56608.1 - 0.0095 16.1 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 AEO56608.1 - 0.012 16.1 0.0 0.02 15.3 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeats (many copies) SAM_decarbox PF01536.11 AEO56609.1 - 1.9e-87 293.0 0.0 5.3e-85 285.0 0.0 3.1 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase ParA PF10609.4 AEO56610.1 - 4.7e-36 122.5 0.0 8.6e-36 121.6 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 AEO56610.1 - 1.2e-13 50.9 0.0 2.5e-13 49.8 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 AEO56610.1 - 1.4e-06 27.5 0.0 2.7e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 ATPase MipZ AAA_31 PF13614.1 AEO56610.1 - 2.1e-05 24.5 0.0 7.6e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 AEO56610.1 - 2.5e-05 23.4 1.0 4e-05 22.8 0.2 1.7 2 0 0 2 2 2 1 Anion-transporting ATPase ArgK PF03308.11 AEO56610.1 - 0.0012 17.6 0.5 0.0018 17.1 0.3 1.2 1 0 0 1 1 1 1 ArgK protein AAA_25 PF13481.1 AEO56610.1 - 0.003 16.9 0.1 0.0056 16.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_26 PF13500.1 AEO56610.1 - 0.0068 16.0 0.1 1.5 8.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain YhjQ PF06564.7 AEO56610.1 - 0.0086 15.4 0.2 0.013 14.8 0.2 1.4 1 1 0 1 1 1 1 YhjQ protein APS_kinase PF01583.15 AEO56610.1 - 0.056 13.0 0.1 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF258 PF03193.11 AEO56610.1 - 0.077 12.1 1.0 0.14 11.2 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 p450 PF00067.17 AEO56612.1 - 8.6e-94 314.6 0.0 9.9e-94 314.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 AEO56613.1 - 0.0038 16.9 0.2 0.0077 15.9 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 AEO56613.1 - 0.036 13.7 0.3 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 F-box domain CFEM PF05730.6 AEO56614.1 - 3.8e-14 52.2 8.6 5.9e-14 51.6 6.0 1.3 1 0 0 1 1 1 1 CFEM domain DUF1895 PF08988.5 AEO56614.1 - 0.073 13.1 0.2 0.25 11.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1895) EGL-1 PF11430.3 AEO56614.1 - 0.26 10.9 1.9 0.48 10.0 1.3 1.4 1 0 0 1 1 1 0 Programmed cell death activator EGL-1 Glyco_hydr_30_2 PF14587.1 AEO56615.1 - 1.9e-18 66.5 9.1 1.9e-18 66.5 6.3 1.7 1 1 0 2 2 2 1 O-Glycosyl hydrolase family 30 Tox-REase-5 PF15648.1 AEO56616.1 - 0.098 12.9 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 5 F-box-like PF12937.2 AEO56618.1 - 0.00093 18.8 0.1 0.002 17.7 0.0 1.6 1 0 0 1 1 1 1 F-box-like DUF2457 PF10446.4 AEO56618.1 - 0.59 8.8 12.8 0.81 8.3 8.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Formyl_trans_N PF00551.14 AEO56619.1 - 2.2e-37 128.3 0.0 2.7e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase Podoplanin PF05808.6 AEO56620.1 - 0.0005 19.6 1.3 0.00087 18.8 0.9 1.3 1 0 0 1 1 1 1 Podoplanin DUF4366 PF14283.1 AEO56620.1 - 0.027 13.9 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) PDGLE PF13190.1 AEO56620.1 - 0.12 12.0 0.4 0.3 10.7 0.3 1.7 1 0 0 1 1 1 0 PDGLE domain Adeno_E3_CR2 PF02439.10 AEO56620.1 - 0.15 11.6 0.1 0.24 10.9 0.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Beta-APP PF03494.8 AEO56620.1 - 1 8.8 6.5 6.5 6.3 3.4 2.3 2 0 0 2 2 2 0 Beta-amyloid peptide (beta-APP) DUF605 PF04652.11 AEO56620.1 - 9.1 5.5 29.1 1.7 7.9 11.2 2.2 2 0 0 2 2 2 0 Vta1 like Alpha_GJ PF03229.8 AEO56620.1 - 9.4 6.5 9.6 7.9 6.8 5.0 2.1 1 1 1 2 2 2 0 Alphavirus glycoprotein J 2-Hacid_dh_C PF02826.14 AEO56621.1 - 1.3e-37 128.6 0.0 2e-37 128.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 AEO56621.1 - 7.7e-11 41.5 0.0 1.1e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 AEO56621.1 - 0.003 17.4 0.0 0.0059 16.4 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 AEO56621.1 - 0.0086 16.4 0.0 0.024 15.0 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DLH PF01738.13 AEO56622.1 - 1.8e-12 47.0 0.1 3.5e-11 42.7 0.0 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 AEO56622.1 - 3.4e-07 30.1 0.3 4.4e-07 29.7 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AEO56622.1 - 8.3e-06 25.8 6.9 0.0019 18.1 4.8 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 AEO56622.1 - 0.0046 16.2 0.2 0.018 14.2 0.0 2.0 3 0 0 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 AEO56622.1 - 0.015 14.9 0.0 4.2 6.8 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold Ammonium_transp PF00909.16 AEO56623.1 - 2.3e-119 398.4 27.7 2.6e-119 398.2 19.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family UQ_con PF00179.21 AEO56624.1 - 2.6e-23 81.9 0.0 5.6e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme IBR PF01485.16 AEO56624.1 - 0.02 14.7 0.6 0.055 13.3 0.4 1.7 1 0 0 1 1 1 0 IBR domain UEV PF05743.8 AEO56624.1 - 0.049 13.3 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 UEV domain Cyclin_N PF00134.18 AEO56625.1 - 2.9e-06 26.8 0.0 9.1e-06 25.2 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Trans_reg_C PF00486.23 AEO56625.1 - 0.11 12.4 0.3 0.27 11.1 0.2 1.6 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal BAR PF03114.13 AEO56626.1 - 8.8e-52 175.8 7.0 1.2e-51 175.4 4.9 1.2 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.4 AEO56626.1 - 1e-06 27.9 2.3 2e-06 26.9 1.6 1.4 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Phage_GP20 PF06810.6 AEO56626.1 - 0.17 11.2 3.6 0.3 10.4 2.1 1.7 2 0 0 2 2 2 0 Phage minor structural protein GP20 APG6 PF04111.7 AEO56626.1 - 0.88 8.5 7.3 1.5 7.7 5.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 AEO56626.1 - 2.3 7.7 5.4 3.7 7.1 3.8 1.3 1 0 0 1 1 1 0 IncA protein BAR PF03114.13 AEO56627.1 - 5.6e-64 215.7 3.7 6.9e-64 215.4 2.6 1.1 1 0 0 1 1 1 1 BAR domain Pept_tRNA_hydro PF01195.14 AEO56628.1 - 7.5e-27 94.0 0.0 9e-27 93.7 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase Epimerase PF01370.16 AEO56629.1 - 8.8e-26 90.7 0.0 1.1e-25 90.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 AEO56629.1 - 5.6e-10 38.5 0.1 7e-09 34.9 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 AEO56629.1 - 7.5e-10 39.1 0.1 3.7e-09 36.8 0.1 2.0 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 AEO56629.1 - 1.3e-08 33.8 0.0 2.9e-08 32.7 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 AEO56629.1 - 7.3e-07 28.6 0.0 0.00033 19.9 0.0 2.2 2 0 0 2 2 2 2 NmrA-like family KR PF08659.5 AEO56629.1 - 1.6e-06 27.8 1.1 0.00013 21.6 0.8 2.5 1 1 0 1 1 1 1 KR domain adh_short PF00106.20 AEO56629.1 - 1.3e-05 25.2 5.0 2e-05 24.5 0.4 3.0 2 1 1 3 3 3 1 short chain dehydrogenase DUF1996 PF09362.5 AEO56635.1 - 1.6e-70 237.4 1.5 2e-70 237.1 1.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) TauD PF02668.11 AEO56636.1 - 6.1e-28 98.1 0.1 1.1e-27 97.2 0.0 1.4 1 1 1 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family LssY_C PF14067.1 AEO56636.1 - 0.061 12.2 0.0 1.4 7.9 0.0 2.2 2 0 0 2 2 2 0 LssY C-terminus Glyco_hydro_47 PF01532.15 AEO56637.1 - 2.5e-169 563.7 0.0 2.9e-169 563.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF1680 PF07944.7 AEO56637.1 - 0.011 14.0 0.1 0.032 12.4 0.0 1.7 2 0 0 2 2 2 0 Putative glycosyl hydrolase of unknown function (DUF1680) PT PF04886.7 AEO56637.1 - 0.95 8.8 6.3 2 7.7 0.4 2.3 2 0 0 2 2 2 0 PT repeat Chromate_transp PF02417.10 AEO56638.1 - 1.4e-50 171.1 38.1 1.1e-27 96.7 10.4 2.5 3 0 0 3 3 3 2 Chromate transporter HAMP PF00672.20 AEO56638.1 - 0.28 11.3 0.1 0.28 11.3 0.0 3.8 4 0 0 4 4 4 0 HAMP domain Fasciclin PF02469.17 AEO56639.1 - 1.5e-42 144.6 0.9 1.5e-24 86.4 0.0 2.1 2 0 0 2 2 2 2 Fasciclin domain DUF1883 PF08980.5 AEO56639.1 - 0.029 13.9 0.0 0.053 13.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1883) CENP-F_leu_zip PF10473.4 AEO56640.1 - 0.00042 20.1 51.0 0.057 13.2 8.0 4.6 1 1 2 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_tail_1 PF01576.14 AEO56640.1 - 0.0062 14.3 55.2 0.014 13.1 20.4 3.0 1 1 1 3 3 3 2 Myosin tail GIDA_assoc_3 PF13932.1 AEO56640.1 - 0.016 15.2 0.4 0.088 12.8 0.3 2.4 1 0 0 1 1 1 0 GidA associated domain 3 DUF2682 PF10909.3 AEO56640.1 - 0.13 12.5 5.9 5.3 7.3 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2682) Filament PF00038.16 AEO56640.1 - 0.17 11.3 46.3 0.51 9.7 6.1 3.9 1 1 2 3 3 3 0 Intermediate filament protein Reo_sigmaC PF04582.7 AEO56640.1 - 0.95 8.5 17.1 1.7 7.7 0.2 3.5 1 1 1 3 3 3 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 AEO56640.1 - 2.6 7.8 17.2 1.8 8.3 0.4 4.5 2 2 3 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus KNOX2 PF03791.8 AEO56640.1 - 6.8 6.0 7.5 4.6 6.5 0.1 3.3 4 0 0 4 4 4 0 KNOX2 domain Exo_endo_phos PF03372.18 AEO56641.1 - 7.3e-16 58.8 0.1 1.2e-15 58.1 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PapD-like PF14874.1 AEO56641.1 - 0.02 14.8 0.0 0.046 13.6 0.0 1.6 1 0 0 1 1 1 0 Flagellar-associated PapD-like Lantibiotic_a PF14867.1 AEO56641.1 - 0.044 13.0 0.6 0.1 11.8 0.4 1.5 1 0 0 1 1 1 0 Lantibiotic alpha Glyco_hydro_61 PF03443.9 AEO56642.1 - 5.5e-63 212.6 0.1 6.5e-63 212.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Ribonuclease PF00545.15 AEO56643.1 - 5.3e-18 64.8 0.1 6.6e-18 64.5 0.1 1.2 1 0 0 1 1 1 1 ribonuclease Swi5 PF07061.6 AEO56644.1 - 8.1e-22 76.8 0.0 1.5e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 Swi5 DCP1 PF06058.8 AEO56644.1 - 2.1e-13 50.4 0.0 4.8e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Dcp1-like decapping family DUF4051 PF13260.1 AEO56644.1 - 0.11 11.7 0.0 0.25 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) Pyr_redox_3 PF13738.1 AEO56645.1 - 1.6e-24 87.0 0.0 7.9e-24 84.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 AEO56645.1 - 1.6e-06 27.3 0.0 3.8e-06 26.0 0.0 1.5 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 AEO56645.1 - 1.3e-05 23.5 0.0 2.2e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 AEO56645.1 - 1.6e-05 24.8 0.0 0.0084 16.0 0.0 3.4 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AEO56645.1 - 2.6e-05 24.1 0.0 0.00021 21.2 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 AEO56645.1 - 0.0063 16.3 0.0 0.49 10.1 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 AEO56645.1 - 0.0065 16.5 0.1 0.031 14.3 0.0 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 AEO56645.1 - 0.011 14.8 0.0 0.022 13.9 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 AEO56645.1 - 0.16 12.3 0.0 30 4.9 0.0 2.5 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Cyclase PF04199.8 AEO56646.1 - 5e-15 55.6 0.2 7.3e-15 55.0 0.2 1.2 1 0 0 1 1 1 1 Putative cyclase SKG6 PF08693.5 AEO56647.1 - 0.015 14.5 0.9 0.034 13.4 0.6 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain hEGF PF12661.2 AEO56647.1 - 0.88 9.7 9.0 9.8 6.5 0.2 3.8 3 0 0 3 3 3 0 Human growth factor-like EGF cEGF PF12662.2 AEO56647.1 - 1 9.0 14.9 11 5.7 0.4 3.6 3 0 0 3 3 3 0 Complement Clr-like EGF-like GST_C_3 PF14497.1 AEO56648.1 - 1.8e-09 37.9 0.0 2.8e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 AEO56648.1 - 0.0018 18.1 0.0 0.0037 17.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 AEO56648.1 - 0.023 14.9 0.0 0.19 11.9 0.0 2.3 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Sugar_tr PF00083.19 AEO56649.1 - 2.2e-67 227.5 14.6 2.5e-67 227.4 10.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO56649.1 - 1.7e-12 46.7 28.3 1.7e-12 46.7 19.6 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily ABC2_membrane_5 PF13346.1 AEO56649.1 - 8.7 5.5 8.2 3.1 7.0 2.9 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein Glyco_hydro_35 PF01301.14 AEO56651.1 - 5.5e-18 65.3 0.0 7.4e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 AEO56651.1 - 0.0012 19.0 0.0 0.042 14.1 0.0 2.5 3 0 0 3 3 3 1 Beta-galactosidase jelly roll domain F-box-like PF12937.2 AEO56652.1 - 2.4e-13 49.5 1.4 2.4e-13 49.5 1.0 2.4 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 AEO56652.1 - 1.8e-11 43.4 10.6 0.06 12.9 0.0 7.6 7 0 0 7 7 7 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 AEO56652.1 - 5.1e-10 38.3 17.7 0.17 12.0 0.0 11.4 12 0 0 12 12 12 2 Leucine Rich repeat LRR_8 PF13855.1 AEO56652.1 - 2.4e-06 27.1 17.2 0.22 11.3 0.2 6.7 3 1 3 7 7 7 5 Leucine rich repeat F-box PF00646.28 AEO56652.1 - 4e-05 23.1 0.8 0.00014 21.3 0.6 2.0 1 0 0 1 1 1 1 F-box domain LRR_1 PF00560.28 AEO56652.1 - 0.0003 20.4 26.3 12 6.3 0.0 10.1 9 2 1 10 10 10 1 Leucine Rich Repeat DUF1699 PF08004.6 AEO56652.1 - 0.078 12.5 1.4 29 4.2 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1699) Chalcone PF02431.10 AEO56653.1 - 2.5e-60 203.2 0.0 3.1e-60 202.9 0.0 1.1 1 0 0 1 1 1 1 Chalcone-flavanone isomerase BAG PF02179.11 AEO56654.1 - 8.7e-13 48.1 0.3 1.4e-12 47.5 0.2 1.3 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.18 AEO56654.1 - 0.0011 18.3 0.0 0.002 17.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L13 PF00572.13 AEO56655.1 - 9.3e-28 96.8 0.0 1.7e-27 96.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L13 DSBA PF01323.15 AEO56655.1 - 0.089 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 DSBA-like thioredoxin domain Pkinase PF00069.20 AEO56656.1 - 3.5e-18 65.6 0.0 6.9e-18 64.7 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO56656.1 - 5.1e-18 65.0 0.0 4.4e-17 62.0 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 AEO56656.1 - 0.034 13.5 0.0 0.053 12.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 AEO56656.1 - 0.058 12.4 0.0 0.088 11.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Radical_SAM PF04055.16 AEO56657.1 - 4e-16 59.6 0.0 1.3e-15 57.9 0.0 1.8 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 AEO56657.1 - 4.7e-13 48.9 0.0 2.9e-12 46.4 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family CoA_binding PF02629.14 AEO56658.1 - 3.2e-28 98.0 4.0 2.1e-27 95.4 0.7 2.3 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 AEO56658.1 - 2.2e-24 85.7 0.1 3.8e-24 85.0 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 AEO56658.1 - 1.3e-08 34.5 0.0 2.2e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 AEO56658.1 - 0.0002 21.4 0.1 0.00057 20.0 0.1 1.8 1 0 0 1 1 1 1 CoA binding domain GFO_IDH_MocA PF01408.17 AEO56658.1 - 0.0029 18.1 0.1 0.0056 17.1 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold UQ_con PF00179.21 AEO56659.1 - 6.7e-39 132.5 0.0 8.5e-39 132.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 AEO56659.1 - 2.5e-06 26.9 0.1 4.6e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.1 AEO56659.1 - 0.00018 21.2 0.0 0.00028 20.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 AEO56659.1 - 0.058 13.0 0.1 0.086 12.5 0.0 1.3 1 0 0 1 1 1 0 UEV domain AAA PF00004.24 AEO56660.1 - 3.6e-41 140.4 0.0 6.3e-41 139.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AEO56660.1 - 5.5e-07 29.7 0.1 0.00019 21.5 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 AEO56660.1 - 2e-06 27.8 0.0 4.2e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 AEO56660.1 - 9.8e-06 24.6 0.0 1.8e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 AEO56660.1 - 3.9e-05 23.4 0.1 0.00013 21.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 AEO56660.1 - 0.00029 20.8 1.5 0.001 19.1 0.1 2.5 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 AEO56660.1 - 0.00035 19.7 0.0 0.00064 18.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 AEO56660.1 - 0.00093 19.1 0.3 0.004 17.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 AEO56660.1 - 0.0022 17.8 0.0 0.004 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 AEO56660.1 - 0.0038 16.9 0.2 0.35 10.5 0.0 2.8 2 1 1 3 3 3 1 NACHT domain AAA_19 PF13245.1 AEO56660.1 - 0.0062 16.2 0.3 0.015 14.9 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 AEO56660.1 - 0.0064 17.3 1.1 0.013 16.3 0.1 2.1 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 AEO56660.1 - 0.0068 15.8 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 AEO56660.1 - 0.0075 16.1 0.2 0.022 14.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 AEO56660.1 - 0.0085 15.1 0.0 0.017 14.2 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 AEO56660.1 - 0.01 16.1 0.0 0.025 14.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 AEO56660.1 - 0.013 15.0 0.0 0.029 13.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 AEO56660.1 - 0.015 14.5 1.9 0.21 10.7 0.1 2.2 2 0 0 2 2 2 0 PhoH-like protein TIP49 PF06068.8 AEO56660.1 - 0.02 13.6 0.1 0.046 12.4 0.1 1.6 1 1 0 1 1 1 0 TIP49 C-terminus NB-ARC PF00931.17 AEO56660.1 - 0.039 12.8 0.0 0.065 12.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain KaiC PF06745.8 AEO56660.1 - 0.042 12.9 0.2 0.43 9.6 0.1 2.2 1 1 1 2 2 2 0 KaiC RNA_helicase PF00910.17 AEO56660.1 - 0.046 13.9 0.0 0.087 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.16 AEO56660.1 - 0.055 12.6 0.1 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 AEO56660.1 - 0.055 13.0 0.2 0.14 11.7 0.2 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 AEO56660.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 AEO56660.1 - 0.23 10.8 5.9 0.26 10.6 0.3 2.7 2 1 0 3 3 3 0 AAA domain Pkinase PF00069.20 AEO56661.1 - 5.9e-12 45.2 0.0 8.6e-12 44.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO56661.1 - 4.9e-07 29.0 0.0 6.8e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AEO56661.1 - 3e-06 27.1 0.2 5.8e-06 26.2 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 AEO56661.1 - 0.00014 20.9 0.0 0.00022 20.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 AEO56661.1 - 0.00036 19.9 0.0 0.00058 19.2 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 AEO56661.1 - 0.003 17.1 0.0 0.0046 16.5 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.1 AEO56661.1 - 0.0089 15.0 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Acetyltransf_7 PF13508.1 AEO56663.1 - 6.4e-10 39.0 0.0 1.1e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 AEO56663.1 - 4.3e-08 33.0 0.1 1.1e-07 31.8 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 AEO56663.1 - 4e-06 26.6 0.0 8e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 AEO56663.1 - 4.1e-06 26.8 0.1 1.6e-05 25.0 0.0 2.0 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 AEO56663.1 - 2.1e-05 24.1 0.0 4.1e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_6 PF13480.1 AEO56663.1 - 0.056 13.3 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 AEO56663.1 - 0.082 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Glyco_hydro_61 PF03443.9 AEO56665.1 - 1.4e-51 175.3 0.2 1.7e-51 175.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MUG113 PF13455.1 AEO56667.1 - 1.8e-32 111.5 0.2 3.7e-32 110.6 0.2 1.5 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 AEO56667.1 - 1.9e-23 82.7 0.5 5e-23 81.3 0.3 1.7 1 0 0 1 1 1 1 T5orf172 domain PBP1_TM PF14812.1 AEO56667.1 - 0.88 9.9 5.2 0.49 10.7 1.5 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3602 PF12223.3 AEO56668.1 - 0.1 13.0 0.1 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3602) Sod_Fe_N PF00081.17 AEO56669.1 - 1.2e-34 118.4 3.2 1.2e-34 118.4 2.2 1.9 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.13 AEO56669.1 - 2.3e-34 117.4 0.2 4.2e-34 116.5 0.2 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Spherulin4 PF12138.3 AEO56670.1 - 1.2e-41 142.8 0.0 2.4e-41 141.8 0.0 1.4 2 0 0 2 2 2 1 Spherulation-specific family 4 CVNH PF08881.5 AEO56671.1 - 3.7e-11 43.1 0.0 4.3e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 CVNH domain EGF_3 PF12947.2 AEO56671.1 - 1.2 9.1 5.5 3.7 7.5 0.8 2.6 2 0 0 2 2 2 0 EGF domain DUF2305 PF10230.4 AEO56672.1 - 7.7e-62 209.1 0.0 9.8e-62 208.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 AEO56672.1 - 2e-08 34.3 1.2 3e-08 33.8 0.8 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO56672.1 - 0.00029 20.6 0.0 0.00042 20.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO56672.1 - 0.015 14.8 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 AEO56672.1 - 0.018 14.5 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.8 AEO56672.1 - 0.15 11.6 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein S1FA PF04689.8 AEO56673.1 - 0.0057 16.4 0.2 0.024 14.5 0.0 2.0 2 0 0 2 2 2 1 DNA binding protein S1FA ABC_tran PF00005.22 AEO56674.1 - 1.4e-47 161.4 0.0 8.4e-24 84.4 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_tran_2 PF12848.2 AEO56674.1 - 4.1e-22 77.8 2.4 4.1e-22 77.8 1.7 2.6 3 0 0 3 3 1 1 ABC transporter AAA_21 PF13304.1 AEO56674.1 - 3.6e-19 69.8 0.0 0.0011 18.9 0.0 4.2 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 AEO56674.1 - 8.9e-11 41.4 0.1 0.004 16.4 0.0 4.4 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 AEO56674.1 - 1.8e-09 37.0 0.2 0.00085 18.8 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 AEO56674.1 - 2.7e-08 34.3 3.1 0.03 14.6 0.1 3.4 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 AEO56674.1 - 1.9e-07 31.9 0.1 0.002 18.9 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 AEO56674.1 - 8.9e-07 29.1 0.0 0.043 13.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 AEO56674.1 - 9.6e-07 29.1 0.3 0.043 14.1 0.0 3.2 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 AEO56674.1 - 1.6e-06 27.4 0.0 0.0028 16.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_28 PF13521.1 AEO56674.1 - 2.2e-06 27.7 0.0 0.002 18.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 AEO56674.1 - 6.6e-06 26.0 0.0 0.047 13.6 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 AEO56674.1 - 1.2e-05 25.7 0.0 0.049 14.1 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_33 PF13671.1 AEO56674.1 - 1.2e-05 25.1 0.1 0.25 11.1 0.1 3.4 4 0 0 4 4 3 2 AAA domain NACHT PF05729.7 AEO56674.1 - 1.3e-05 24.8 0.3 0.16 11.5 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA PF00004.24 AEO56674.1 - 1.9e-05 24.8 0.1 0.24 11.5 0.0 3.2 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 AEO56674.1 - 4.7e-05 23.4 1.4 0.24 11.3 0.1 3.1 2 2 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 AEO56674.1 - 4.8e-05 22.8 0.0 0.19 11.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.9 AEO56674.1 - 0.00012 21.8 0.2 0.67 9.6 0.1 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 AEO56674.1 - 0.00014 22.0 1.6 1.4 9.1 0.0 3.3 3 0 0 3 3 3 2 RNA helicase Arch_ATPase PF01637.13 AEO56674.1 - 0.00033 20.4 0.2 0.41 10.2 0.0 3.0 3 0 0 3 3 3 1 Archaeal ATPase AAA_15 PF13175.1 AEO56674.1 - 0.0004 19.5 0.0 0.17 10.8 0.0 2.9 3 1 0 3 3 3 1 AAA ATPase domain AAA_14 PF13173.1 AEO56674.1 - 0.0006 19.7 0.0 1.5 8.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.18 AEO56674.1 - 0.0007 19.4 0.8 1 9.1 0.0 3.7 3 1 0 4 4 4 1 Dynamin family AAA_10 PF12846.2 AEO56674.1 - 0.001 18.6 1.6 0.89 8.9 0.2 3.0 4 0 0 4 4 2 2 AAA-like domain MobB PF03205.9 AEO56674.1 - 0.0023 17.6 0.5 0.14 11.8 0.1 2.8 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 AEO56674.1 - 0.0041 16.0 0.0 1.2 7.9 0.0 3.0 3 0 0 3 3 3 1 NB-ARC domain DUF2813 PF11398.3 AEO56674.1 - 0.0061 15.6 1.9 0.86 8.6 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF2813) UvsY PF11056.3 AEO56674.1 - 0.011 15.8 0.5 0.062 13.4 0.8 1.9 2 0 0 2 2 1 0 Recombination, repair and ssDNA binding protein UvsY SbcCD_C PF13558.1 AEO56674.1 - 0.017 15.0 0.8 0.66 9.9 0.1 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DAP3 PF10236.4 AEO56674.1 - 0.018 13.9 1.7 2.6 6.8 0.0 3.1 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 ATP-synt_ab PF00006.20 AEO56674.1 - 0.037 13.5 0.0 0.36 10.2 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_13 PF13166.1 AEO56674.1 - 0.042 12.3 0.1 13 4.0 0.0 3.2 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.10 AEO56674.1 - 0.046 13.4 0.4 6.2 6.5 0.2 2.6 2 0 0 2 2 2 0 NTPase DUF815 PF05673.8 AEO56674.1 - 0.049 12.5 0.1 2 7.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) VirE PF05272.6 AEO56674.1 - 0.05 13.0 0.1 5.3 6.4 0.0 2.9 3 0 0 3 3 3 0 Virulence-associated protein E Adeno_IVa2 PF02456.10 AEO56674.1 - 0.055 12.1 0.5 2.2 6.8 0.0 2.5 3 0 0 3 3 2 0 Adenovirus IVa2 protein FeoB_N PF02421.13 AEO56674.1 - 0.075 12.3 0.2 12 5.1 0.0 3.0 3 0 0 3 3 3 0 Ferrous iron transport protein B PduV-EutP PF10662.4 AEO56674.1 - 0.078 12.4 0.8 6.8 6.1 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.12 AEO56674.1 - 0.13 12.0 2.3 12 5.6 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF87 MCM PF00493.18 AEO56674.1 - 0.28 9.9 2.3 13 4.5 0.0 2.7 3 0 0 3 3 3 0 MCM2/3/5 family DUF3584 PF12128.3 AEO56674.1 - 9.8 3.3 7.5 0.37 8.0 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) SNF2_N PF00176.18 AEO56676.1 - 1.9e-71 240.3 1.7 3.3e-71 239.5 1.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.1 AEO56676.1 - 3.2e-51 173.0 17.2 3.2e-51 173.0 11.9 4.7 4 1 1 5 5 5 1 DNA-binding domain Helicase_C PF00271.26 AEO56676.1 - 4.7e-16 58.4 0.0 1.4e-15 56.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Baculo_p74_N PF08404.5 AEO56677.1 - 0.052 12.3 0.0 0.072 11.8 0.0 1.2 1 0 0 1 1 1 0 Baculoviridae P74 N-terminal NfeD PF01957.13 AEO56677.1 - 1.3 9.1 8.5 1.8 8.7 5.9 1.2 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding Peptidase_M50 PF02163.17 AEO56677.1 - 8.3 5.3 7.5 11 4.9 5.2 1.2 1 0 0 1 1 1 0 Peptidase family M50 DUF4464 PF14713.1 AEO56678.1 - 0.02 14.2 0.1 0.032 13.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4464) Luteo_P1-P2 PF08467.5 AEO56679.1 - 0.0023 16.8 0.4 0.0028 16.5 0.3 1.1 1 0 0 1 1 1 1 Luteovirus RNA polymerase P1-P2/replicase BRE1 PF08647.6 AEO56679.1 - 0.025 14.5 1.1 0.025 14.5 0.7 1.9 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Rop-like PF05082.8 AEO56679.1 - 0.026 13.9 0.5 0.076 12.4 0.3 1.8 1 0 0 1 1 1 0 Rop-like SR-25 PF10500.4 AEO56679.1 - 0.027 13.9 0.6 0.027 13.9 0.4 1.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein REV PF00424.13 AEO56679.1 - 0.043 13.7 0.0 0.069 13.0 0.0 1.3 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) DUF4200 PF13863.1 AEO56679.1 - 8.8 6.2 8.3 0.83 9.6 2.7 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) GFO_IDH_MocA PF01408.17 AEO56680.1 - 7.5e-26 91.0 0.1 1.1e-25 90.4 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 AEO56680.1 - 3.4e-13 49.3 0.0 6.3e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.19 AEO56680.1 - 2.7e-07 30.9 0.0 4.5e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_3 PF03447.11 AEO56680.1 - 5.6e-05 23.5 0.1 0.00011 22.6 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain CoA_binding_2 PF13380.1 AEO56680.1 - 0.011 15.9 0.2 0.023 14.8 0.1 1.5 1 0 0 1 1 1 0 CoA binding domain Saccharop_dh PF03435.13 AEO56680.1 - 0.038 12.9 0.1 0.061 12.3 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase AAA_33 PF13671.1 AEO56680.1 - 0.038 13.8 0.1 0.12 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain DapB_N PF01113.15 AEO56680.1 - 0.067 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Peripla_BP_6 PF13458.1 AEO56680.1 - 0.074 12.3 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 Periplasmic binding protein Histidinol_dh PF00815.15 AEO56680.1 - 0.15 10.6 0.1 0.22 10.1 0.1 1.1 1 0 0 1 1 1 0 Histidinol dehydrogenase Glyco_hydro_72 PF03198.9 AEO56681.1 - 3.3e-124 413.9 1.3 4.4e-124 413.5 0.9 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 AEO56681.1 - 1.5e-24 86.2 4.4 3.4e-24 85.1 3.0 1.6 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.12 AEO56681.1 - 1.1e-05 24.5 0.0 1.7e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF4156 PF13698.1 AEO56682.1 - 0.68 9.8 2.7 0.27 11.1 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4156) Lipoxygenase PF00305.14 AEO56683.1 - 1.7e-56 191.6 1.4 6.5e-55 186.3 0.3 2.0 2 0 0 2 2 2 2 Lipoxygenase Arylesterase PF01731.15 AEO56685.1 - 0.038 13.9 0.0 0.37 10.7 0.0 2.4 1 1 0 1 1 1 0 Arylesterase Oxidored_FMN PF00724.15 AEO56686.1 - 0.00016 20.7 0.0 0.00018 20.6 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Peptidase_M20 PF01546.23 AEO56687.1 - 3.7e-08 33.0 0.2 5.8e-08 32.4 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 AEO56687.1 - 5.9e-07 29.2 0.0 2.9e-06 26.9 0.0 2.2 2 1 0 2 2 2 1 Peptidase dimerisation domain Ytp1 PF10355.4 AEO56688.1 - 6.5e-86 287.8 16.6 1e-85 287.2 11.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 AEO56688.1 - 5.5e-34 115.9 0.8 5.5e-34 115.9 0.5 2.8 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) GFA PF04828.9 AEO56689.1 - 2.1e-13 50.0 13.4 2.8e-07 30.4 0.0 4.7 4 1 0 4 4 4 2 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.6 AEO56689.1 - 0.044 13.3 0.4 0.044 13.3 0.3 3.7 4 0 0 4 4 4 0 NADH pyrophosphatase zinc ribbon domain FTA2 PF13095.1 AEO56690.1 - 0.00012 21.7 0.0 0.024 14.2 0.0 2.1 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 adh_short PF00106.20 AEO56691.1 - 3.9e-05 23.6 0.9 0.00013 21.8 0.0 2.2 1 1 1 2 2 2 1 short chain dehydrogenase Glyco_hydro_43 PF04616.9 AEO56692.1 - 1.3e-66 224.6 1.2 1.6e-66 224.2 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Fungal_trans_2 PF11951.3 AEO56693.1 - 6.7e-09 34.8 0.3 4.3e-08 32.1 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO56693.1 - 5.8e-07 29.3 11.4 1.1e-06 28.3 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_4 PF01565.18 AEO56694.1 - 3.4e-27 94.6 6.4 9.1e-27 93.2 4.5 1.8 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 AEO56694.1 - 1.2e-13 50.7 0.1 2.4e-13 49.7 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like Proteasom_PSMB PF10508.4 AEO56695.1 - 0.16 10.2 0.1 0.25 9.5 0.1 1.2 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit GRP PF07172.6 AEO56695.1 - 3.1 8.3 18.0 5.9 7.4 12.5 1.3 1 0 0 1 1 1 0 Glycine rich protein family Lipase_3 PF01764.20 AEO56697.1 - 7.8e-19 67.6 0.0 1.7e-18 66.5 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) YokU PF14122.1 AEO56697.1 - 0.14 11.9 0.0 0.76 9.5 0.0 2.1 2 0 0 2 2 2 0 YokU-like protein DUF89 PF01937.14 AEO56698.1 - 5.9e-127 423.3 0.0 7e-127 423.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF89 Suf PF05843.9 AEO56698.1 - 0.041 13.6 0.1 0.06 13.0 0.1 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF663 PF04950.7 AEO56698.1 - 0.073 12.0 0.2 0.11 11.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF663) Spt20 PF12090.3 AEO56698.1 - 0.075 12.3 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 Spt20 family DUF1840 PF08895.6 AEO56698.1 - 0.57 10.2 6.8 0.091 12.7 2.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) zf-C3HC4_2 PF13923.1 AEO56700.1 - 0.017 15.1 3.4 0.017 15.1 2.4 3.2 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) TPR_11 PF13414.1 AEO56701.1 - 1.2e-16 60.1 1.6 2.5e-12 46.2 0.4 2.5 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 AEO56701.1 - 1.1e-12 46.8 8.5 0.00026 20.6 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 AEO56701.1 - 3.3e-11 42.3 2.8 0.0097 15.4 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 AEO56701.1 - 3.9e-09 36.3 1.6 2.8e-06 27.1 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 AEO56701.1 - 5.5e-07 28.9 0.2 0.26 11.1 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 AEO56701.1 - 7.4e-07 29.6 1.8 7.4e-07 29.6 1.3 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 AEO56701.1 - 2.2e-05 24.7 0.4 0.00096 19.4 0.0 2.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 AEO56701.1 - 3.1e-05 24.2 6.1 0.032 14.8 0.2 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 AEO56701.1 - 0.00013 21.4 2.6 0.39 10.6 0.0 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 AEO56701.1 - 0.00025 20.8 8.9 0.055 13.3 0.4 3.4 2 1 2 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 AEO56701.1 - 0.0027 17.7 0.0 0.0075 16.3 0.0 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 AEO56701.1 - 0.005 16.9 1.3 0.2 11.9 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 AEO56701.1 - 0.0052 17.1 3.7 1.2 9.7 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.9 AEO56701.1 - 0.021 15.2 12.1 0.35 11.4 0.1 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 AEO56701.1 - 8.2 6.5 11.5 3.2 7.7 0.1 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat Zn_clus PF00172.13 AEO56702.1 - 1.7 8.6 9.5 4.1 7.3 6.6 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain TauD PF02668.11 AEO56703.1 - 2.8e-27 96.0 0.0 3.9e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 AEO56703.1 - 0.15 10.9 0.0 0.22 10.4 0.0 1.1 1 0 0 1 1 1 0 CsiD Acyltransferase PF01553.16 AEO56704.1 - 2.2e-25 88.5 0.0 3.1e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase DUF1907 PF08925.6 AEO56704.1 - 0.18 10.8 0.0 0.27 10.2 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1907) NAD_kinase PF01513.16 AEO56705.1 - 9.8e-48 162.3 0.0 3.6e-47 160.5 0.0 1.7 1 1 0 1 1 1 1 ATP-NAD kinase CFEM PF05730.6 AEO56706.1 - 2.2e-13 49.8 8.5 3.4e-13 49.2 5.9 1.3 1 0 0 1 1 1 1 CFEM domain EHN PF06441.7 AEO56707.1 - 0.51 10.2 5.2 0.42 10.5 1.8 2.2 1 1 1 2 2 2 0 Epoxide hydrolase N terminus GAS PF13851.1 AEO56707.1 - 6.8 5.8 31.2 9.2 5.4 10.2 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding 4HBT_2 PF13279.1 AEO56708.1 - 3.3e-19 69.5 0.1 5.1e-19 68.9 0.1 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 AEO56708.1 - 0.13 12.4 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Thioesterase superfamily Complex1_LYR_2 PF13233.1 AEO56709.1 - 3.5e-06 27.4 0.1 3.9e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 AEO56709.1 - 0.00073 19.2 0.5 0.0014 18.3 0.3 1.6 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 AEO56709.1 - 0.03 14.5 0.4 0.039 14.1 0.3 1.3 1 0 0 1 1 1 0 Complex1_LYR-like Methyltransf_25 PF13649.1 AEO56710.1 - 2e-09 37.7 0.0 4.7e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO56710.1 - 1.2e-07 32.1 0.0 2.5e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO56710.1 - 4.4e-07 30.4 0.0 8.3e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO56710.1 - 2.6e-06 27.2 0.0 2.6e-06 27.2 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO56710.1 - 2.6e-06 27.0 0.0 1.4e-05 24.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO56710.1 - 6.3e-06 26.5 0.0 1.7e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO56710.1 - 3.2e-05 23.9 0.0 0.00012 22.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 AEO56710.1 - 3.9e-05 22.8 0.0 6.1e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF3735 PF12537.3 AEO56710.1 - 0.05 13.6 0.1 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3735) CheR PF01739.13 AEO56710.1 - 0.18 11.1 0.0 1.3 8.2 0.0 2.0 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain Zip PF02535.17 AEO56710.1 - 5.1 6.0 14.2 14 4.5 8.9 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter Exo_endo_phos PF03372.18 AEO56711.1 - 3.7e-23 82.7 0.1 6.3e-23 81.9 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 AEO56711.1 - 1.3e-16 59.8 4.9 1.3e-08 34.2 0.1 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AEO56711.1 - 5.5e-15 54.8 15.2 9.3e-08 31.7 1.1 2.4 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 AEO56711.1 - 1.9e-09 36.2 4.1 0.065 13.2 0.4 4.1 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_7 PF13504.1 AEO56711.1 - 9.7e-06 24.9 4.8 0.31 11.4 0.2 4.1 3 0 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.1 AEO56711.1 - 0.00031 20.4 0.7 0.79 9.9 0.1 3.7 3 0 0 3 3 3 2 Leucine Rich repeat Fungal_trans PF04082.13 AEO56713.1 - 3.2e-10 39.3 0.9 9.1e-10 37.8 0.6 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO56713.1 - 4.3e-10 39.3 9.8 7e-10 38.6 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_2 PF02230.11 AEO56714.1 - 2.7e-22 79.2 0.0 1.1e-08 34.8 0.0 3.1 3 0 0 3 3 3 3 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 AEO56714.1 - 8.4e-10 38.9 1.7 5e-09 36.3 1.2 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 AEO56714.1 - 0.00018 20.7 0.0 0.00038 19.7 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 AEO56714.1 - 0.0022 17.7 0.0 0.016 14.9 0.0 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family LIP PF03583.9 AEO56714.1 - 0.019 14.1 0.2 0.047 12.8 0.0 1.6 2 0 0 2 2 2 0 Secretory lipase Cerato-platanin PF07249.7 AEO56715.1 - 1.2e-56 189.8 2.3 1.4e-56 189.6 1.6 1.0 1 0 0 1 1 1 1 Cerato-platanin Barwin PF00967.12 AEO56715.1 - 0.011 15.4 1.0 0.016 14.8 0.7 1.4 1 1 0 1 1 1 0 Barwin family DUF605 PF04652.11 AEO56716.1 - 0.032 13.6 0.9 0.047 13.0 0.6 1.2 1 0 0 1 1 1 0 Vta1 like Mucin PF01456.12 AEO56716.1 - 0.13 11.9 15.9 0.25 11.1 11.0 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.7 AEO56716.1 - 1.8 6.2 5.5 2.5 5.7 3.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.3 AEO56716.1 - 2.7 7.7 12.9 5 6.8 8.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.6 AEO56716.1 - 8 4.2 17.3 11 3.8 12.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Thioesterase PF00975.15 AEO56717.1 - 5.7e-15 56.1 0.0 1e-13 52.0 0.0 2.1 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.2 AEO56717.1 - 2.8e-08 33.9 0.2 4.6e-08 33.2 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO56717.1 - 0.0027 17.4 0.0 0.0033 17.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO56717.1 - 0.018 14.6 0.0 0.053 13.0 0.0 1.9 1 1 1 2 2 2 0 alpha/beta hydrolase fold Collagen PF01391.13 AEO56717.1 - 0.023 14.2 1.7 0.038 13.5 1.2 1.3 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) FAD_binding_3 PF01494.14 AEO56718.1 - 1.9e-64 217.9 0.0 4e-64 216.9 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 AEO56718.1 - 0.00049 19.1 0.0 0.0066 15.3 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 AEO56718.1 - 0.0013 18.8 0.0 0.0075 16.3 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 AEO56718.1 - 0.079 12.8 0.1 0.18 11.6 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 AEO56718.1 - 0.08 11.8 0.2 0.2 10.5 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein SE PF08491.5 AEO56718.1 - 0.24 10.2 0.0 1.1 8.0 0.0 1.9 1 1 0 1 1 1 0 Squalene epoxidase Kinesin PF00225.18 AEO56719.1 - 8e-106 353.5 0.3 8e-106 353.5 0.2 1.9 2 0 0 2 2 2 1 Kinesin motor domain WEMBL PF05701.6 AEO56719.1 - 0.002 16.6 49.4 0.002 16.6 34.2 1.8 2 0 0 2 2 2 1 Weak chloroplast movement under blue light Reo_sigmaC PF04582.7 AEO56719.1 - 0.21 10.7 9.1 0.13 11.4 1.7 2.6 3 0 0 3 3 3 0 Reovirus sigma C capsid protein Acyltransferase PF01553.16 AEO56720.1 - 0.018 14.4 0.0 0.049 13.0 0.0 1.7 1 1 0 1 1 1 0 Acyltransferase ILVD_EDD PF00920.16 AEO56721.1 - 1e-211 703.9 0.0 1.2e-211 703.7 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family CLP_protease PF00574.18 AEO56722.1 - 1.4e-67 226.9 0.2 1.8e-67 226.5 0.1 1.1 1 0 0 1 1 1 1 Clp protease ECH PF00378.15 AEO56722.1 - 0.057 12.5 0.0 0.096 11.7 0.0 1.3 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase family DNA_primase_lrg PF04104.9 AEO56724.1 - 6.1e-82 274.7 0.0 8.4e-82 274.3 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit DUF3268 PF11672.3 AEO56725.1 - 0.11 12.5 0.4 0.15 12.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3268) DUF1005 PF06219.7 AEO56725.1 - 0.27 9.8 4.2 0.33 9.5 2.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1005) Med25_SD1 PF11235.3 AEO56725.1 - 1.2 9.3 7.0 1.5 9.1 4.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 25 synapsin 1 Ashwin PF15323.1 AEO56725.1 - 1.5 8.7 9.1 1.9 8.4 6.3 1.0 1 0 0 1 1 1 0 Developmental protein DUF508 PF04370.7 AEO56725.1 - 1.7 8.2 8.2 2.2 7.9 5.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF508) DUF605 PF04652.11 AEO56725.1 - 2 7.7 6.5 2 7.6 4.5 1.1 1 0 0 1 1 1 0 Vta1 like DUF515 PF04415.7 AEO56725.1 - 6.6 4.8 12.6 7.4 4.6 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Metallophos PF00149.23 AEO56727.1 - 2.3e-15 56.5 0.2 4.6e-15 55.5 0.1 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 AEO56727.1 - 1.6e-08 34.5 0.0 3.6e-08 33.3 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DnaJ PF00226.26 AEO56728.1 - 9.2e-19 66.9 0.6 2.3e-18 65.6 0.4 1.7 1 0 0 1 1 1 1 DnaJ domain MBOAT PF03062.14 AEO56729.1 - 2.3e-34 118.9 20.2 1.3e-33 116.5 14.0 2.0 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Pkinase PF00069.20 AEO56730.1 - 4e-49 167.1 0.0 2e-48 164.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO56730.1 - 6.8e-28 97.4 0.0 4.4e-27 94.7 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO56730.1 - 0.097 11.6 0.1 0.72 8.7 0.1 2.0 1 1 0 1 1 1 0 Kinase-like HSP90 PF00183.13 AEO56731.1 - 9.1e-261 865.8 30.1 1.1e-260 865.6 20.9 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 AEO56731.1 - 9.6e-12 44.6 0.1 1.7e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 AEO56731.1 - 1.1e-11 44.5 0.2 1.1e-11 44.5 0.1 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1676 PF07898.8 AEO56731.1 - 0.097 12.9 0.3 0.097 12.9 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) PVL_ORF50 PF07768.6 AEO56731.1 - 0.42 10.6 15.0 0.46 10.4 3.9 3.0 3 0 0 3 3 3 0 PVL ORF-50-like family FKBP_C PF00254.23 AEO56732.1 - 6.8e-37 125.3 0.0 7.9e-37 125.1 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Flavin_Reduct PF01613.13 AEO56733.1 - 4e-34 117.6 0.0 6.4e-34 117.0 0.0 1.3 1 0 0 1 1 1 1 Flavin reductase like domain Ribosomal_L31 PF01197.13 AEO56734.1 - 0.0078 16.1 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L31 Vps5 PF09325.5 AEO56735.1 - 5.6e-88 294.1 6.2 9.6e-88 293.4 4.3 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 AEO56735.1 - 3e-25 88.2 0.0 6.7e-25 87.0 0.0 1.6 1 0 0 1 1 1 1 PX domain BAR_2 PF10455.4 AEO56735.1 - 0.003 16.5 5.5 0.0075 15.2 3.8 1.6 2 1 0 2 2 2 1 Bin/amphiphysin/Rvs domain for vesicular trafficking His_Phos_2 PF00328.17 AEO56735.1 - 0.063 12.5 1.2 0.12 11.6 0.8 1.4 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) BAR PF03114.13 AEO56735.1 - 0.064 12.7 6.7 0.13 11.7 4.7 1.5 1 0 0 1 1 1 0 BAR domain WD40 PF00400.27 AEO56736.1 - 1.7e-52 173.5 19.7 4.9e-09 35.7 0.7 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 AEO56736.1 - 1.6e-45 154.7 0.1 2.3e-45 154.1 0.1 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit eIF2A PF08662.6 AEO56736.1 - 7.2e-07 29.1 0.2 0.00025 20.8 0.0 3.4 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A LisH PF08513.6 AEO56736.1 - 0.0015 18.2 0.5 0.0033 17.1 0.0 1.9 2 0 0 2 2 2 1 LisH Nup160 PF11715.3 AEO56736.1 - 0.0074 14.4 4.7 1.5 6.8 0.0 3.6 1 1 2 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 AEO56736.1 - 0.061 12.0 0.0 7.7 5.1 0.0 3.0 2 2 1 4 4 4 0 Nup133 N terminal like IKI3 PF04762.7 AEO56736.1 - 0.1 10.4 0.1 0.37 8.5 0.0 1.9 2 1 1 3 3 3 0 IKI3 family Med11 PF10280.4 AEO56737.1 - 1.6e-34 118.4 0.0 4.3e-34 117.0 0.0 1.6 1 1 0 1 1 1 1 Mediator complex protein Secretin_N_2 PF07655.8 AEO56737.1 - 0.44 10.9 5.9 8.6 6.8 1.0 2.7 2 1 0 2 2 2 0 Secretin N-terminal domain PAN_4 PF14295.1 AEO56738.1 - 0.0025 17.4 1.9 0.0054 16.4 1.3 1.6 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.6 AEO56738.1 - 0.049 13.4 0.3 0.098 12.5 0.2 1.5 1 0 0 1 1 1 0 PAN-like domain Peptidase_M28 PF04389.12 AEO56739.1 - 3e-31 108.5 0.0 4.7e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 AEO56739.1 - 0.049 13.1 0.5 0.11 11.9 0.1 1.4 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 DUF1129 PF06570.6 AEO56739.1 - 4.4 6.5 4.3 12 5.1 3.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) GST_N_3 PF13417.1 AEO56742.1 - 4.9e-14 52.3 0.0 1e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 AEO56742.1 - 1.3e-11 44.4 0.0 2.6e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 AEO56742.1 - 1.9e-11 43.7 0.3 3.7e-11 42.7 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 AEO56742.1 - 5.4e-11 42.3 0.0 1e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 AEO56742.1 - 2.1e-10 40.4 0.0 4.3e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 AEO56742.1 - 1.9e-08 34.6 0.0 3.5e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain FAD_binding_4 PF01565.18 AEO56743.1 - 5.1e-13 48.6 2.1 8.6e-13 47.9 1.5 1.3 1 0 0 1 1 1 1 FAD binding domain Metallophos PF00149.23 AEO56744.1 - 4.1e-13 49.1 0.3 1.1e-12 47.7 0.2 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 AEO56744.1 - 1.9e-05 24.5 0.0 3.8e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Methyltransf_11 PF08241.7 AEO56745.1 - 0.013 15.9 0.0 0.025 15.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 AEO56745.1 - 0.93 8.4 0.0 1.5 7.7 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family SAP PF02037.22 AEO56747.1 - 5e-14 51.3 0.0 1.1e-13 50.2 0.0 1.7 1 0 0 1 1 1 1 SAP domain Ribosomal_L5 PF00281.14 AEO56747.1 - 0.032 14.0 0.0 0.053 13.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L5 HeH PF12949.2 AEO56747.1 - 0.044 13.3 0.1 0.1 12.2 0.1 1.7 1 0 0 1 1 1 0 HeH/LEM domain Sipho_Gp157 PF05565.6 AEO56748.1 - 0.19 11.2 0.6 0.39 10.2 0.4 1.4 1 0 0 1 1 1 0 Siphovirus Gp157 Exo_endo_phos PF03372.18 AEO56750.1 - 1.7e-12 47.7 0.1 2.8e-12 47.0 0.1 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 AEO56750.1 - 0.02 14.4 0.0 0.048 13.2 0.0 1.7 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase RNA_pol_Rpc4 PF05132.9 AEO56751.1 - 4.9 7.1 6.6 24 4.9 1.2 2.6 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF2514 PF10721.4 AEO56752.1 - 0.094 12.4 23.0 1.5 8.4 0.9 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2514) US2 PF02476.10 AEO56752.1 - 2 8.9 8.7 0.17 12.3 0.5 2.7 3 0 0 3 3 3 0 US2 family SPRY PF00622.23 AEO56753.1 - 1.9e-16 60.3 0.0 3e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 SPRY domain Fungal_trans_2 PF11951.3 AEO56754.1 - 1e-08 34.2 1.5 1.6e-08 33.5 0.7 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO56754.1 - 1.5e-08 34.4 11.4 2.3e-08 33.8 7.9 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF859 PF05895.7 AEO56754.1 - 0.13 10.5 0.0 0.18 10.0 0.0 1.1 1 0 0 1 1 1 0 Siphovirus protein of unknown function (DUF859) DUF4175 PF13779.1 AEO56755.1 - 0.0026 15.5 75.2 0.0032 15.2 52.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4175) PAT1 PF09770.4 AEO56755.1 - 0.0035 15.6 74.7 0.0042 15.4 51.8 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 DUF4045 PF13254.1 AEO56755.1 - 0.007 15.6 22.7 0.0075 15.6 15.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4045) SAPS PF04499.10 AEO56755.1 - 0.0074 14.9 20.7 0.0072 15.0 14.3 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein LicD PF04991.8 AEO56755.1 - 0.012 15.7 7.7 0.016 15.2 5.3 1.2 1 0 0 1 1 1 0 LicD family Raftlin PF15250.1 AEO56755.1 - 0.043 12.3 24.5 0.047 12.2 17.0 1.2 1 0 0 1 1 1 0 Raftlin TFIIA PF03153.8 AEO56755.1 - 0.059 13.2 52.0 0.072 12.9 36.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med15 PF09606.5 AEO56755.1 - 0.077 11.1 96.8 0.086 11.0 67.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal BTV_NS2 PF04514.7 AEO56755.1 - 0.087 11.6 19.2 0.11 11.4 13.3 1.4 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 AUX_IAA PF02309.11 AEO56755.1 - 0.12 12.0 24.2 0.15 11.8 16.8 1.3 1 0 0 1 1 1 0 AUX/IAA family Ycf1 PF05758.7 AEO56755.1 - 0.27 8.9 34.3 0.34 8.5 23.8 1.0 1 0 0 1 1 1 0 Ycf1 PLRV_ORF5 PF01690.12 AEO56755.1 - 0.37 9.8 26.8 0.43 9.6 18.6 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Adeno_hexon PF01065.14 AEO56755.1 - 0.38 9.5 17.1 0.41 9.4 11.8 1.1 1 0 0 1 1 1 0 Hexon, adenovirus major coat protein, N-terminal domain Caldesmon PF02029.10 AEO56755.1 - 0.43 8.9 27.0 0.5 8.7 18.7 1.1 1 0 0 1 1 1 0 Caldesmon Hid1 PF12722.2 AEO56755.1 - 0.88 7.1 34.4 1 6.9 23.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Herpes_env PF01673.13 AEO56755.1 - 0.91 8.0 18.4 1.2 7.6 12.8 1.3 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein PA26 PF04636.8 AEO56755.1 - 0.95 8.0 19.9 1 7.9 13.8 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) VID27 PF08553.5 AEO56755.1 - 0.97 7.5 22.4 1.1 7.3 15.5 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein CDC45 PF02724.9 AEO56755.1 - 1.1 7.1 32.3 1.4 6.8 22.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Mem_trans PF03547.13 AEO56755.1 - 1.2 7.3 12.7 1.3 7.2 8.8 1.2 1 0 0 1 1 1 0 Membrane transport protein Cyto_heme_lyase PF01265.12 AEO56755.1 - 1.3 8.5 25.6 1.7 8.1 17.7 1.3 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase DUF2146 PF10220.4 AEO56755.1 - 1.3 6.9 23.3 1.4 6.8 16.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Otopetrin PF03189.8 AEO56755.1 - 1.5 7.7 11.2 1.9 7.3 7.7 1.4 1 0 0 1 1 1 0 Otopetrin RR_TM4-6 PF06459.7 AEO56755.1 - 1.6 8.5 30.7 2.9 7.6 21.3 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF966 PF06136.8 AEO56755.1 - 2 7.7 26.4 2.4 7.4 18.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) RNA_pol_Rpb1_5 PF04998.12 AEO56755.1 - 2 7.5 17.9 2.7 7.1 12.4 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Vfa1 PF08432.5 AEO56755.1 - 2.1 8.3 37.5 2.9 7.8 26.0 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 AvrE PF11725.3 AEO56755.1 - 2.1 5.2 33.2 2.3 5.1 23.0 1.1 1 0 0 1 1 1 0 Pathogenicity factor SPX PF03105.14 AEO56755.1 - 2.9 7.5 30.2 3.5 7.3 20.9 1.2 1 0 0 1 1 1 0 SPX domain GBP_C PF02841.9 AEO56755.1 - 3 6.9 43.0 4.3 6.4 29.8 1.4 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Spore_coat_CotO PF14153.1 AEO56755.1 - 3 7.2 48.7 4.2 6.7 33.7 1.1 1 0 0 1 1 1 0 Spore coat protein CotO DUF4661 PF15576.1 AEO56755.1 - 3.4 7.2 11.1 4.7 6.7 7.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) Exonuc_VII_L PF02601.10 AEO56755.1 - 3.6 6.6 27.6 4.1 6.5 19.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Peptidase_S64 PF08192.6 AEO56755.1 - 3.6 5.7 21.7 3.9 5.7 15.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 Dicty_REP PF05086.7 AEO56755.1 - 3.8 5.1 23.0 4.2 5.0 16.0 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF913 PF06025.7 AEO56755.1 - 4 6.0 17.9 5.7 5.5 12.4 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Pneumo_phosprot PF02478.11 AEO56755.1 - 4.1 6.8 9.6 5.6 6.3 6.6 1.3 1 0 0 1 1 1 0 Pneumovirus phosphoprotein DUF1387 PF07139.6 AEO56755.1 - 4.8 6.6 21.4 7 6.1 14.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Paramyxo_ncap PF00973.14 AEO56755.1 - 4.9 5.7 31.0 6.1 5.4 21.5 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein FLO_LFY PF01698.11 AEO56755.1 - 6.2 5.5 31.4 10 4.8 21.8 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein HEAT_EZ PF13513.1 AEO56756.1 - 2.5e-25 88.2 17.2 9.1e-15 54.6 0.0 11.2 9 2 4 13 13 13 5 HEAT-like repeat HEAT_2 PF13646.1 AEO56756.1 - 6.6e-25 87.2 0.1 1.4e-06 28.5 0.0 7.6 4 3 3 8 8 8 6 HEAT repeats HEAT PF02985.17 AEO56756.1 - 2.1e-24 83.3 12.0 8.5e-06 25.4 0.0 9.2 11 0 0 11 11 11 5 HEAT repeat MMS19_C PF12460.3 AEO56756.1 - 6.5e-10 38.2 2.6 0.0015 17.3 0.0 4.7 4 1 1 5 5 5 3 RNAPII transcription regulator C-terminal Vac14_Fab1_bd PF12755.2 AEO56756.1 - 2.2e-08 34.3 0.3 0.058 13.7 0.0 6.8 6 2 3 9 9 8 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 AEO56756.1 - 8.3e-08 32.2 0.1 0.19 11.5 0.0 5.0 4 1 0 5 5 5 3 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.14 AEO56756.1 - 6.4e-05 22.7 0.4 0.015 15.2 0.1 4.0 3 1 0 3 3 2 1 Importin-beta N-terminal domain Arm PF00514.18 AEO56756.1 - 0.0017 18.1 4.5 0.15 11.9 0.0 5.8 8 0 0 8 8 7 1 Armadillo/beta-catenin-like repeat RIX1 PF08167.7 AEO56756.1 - 0.015 14.9 0.4 14 5.2 0.0 4.6 4 1 2 6 6 6 0 rRNA processing/ribosome biogenesis DUF3437 PF11919.3 AEO56756.1 - 0.11 12.1 0.0 0.63 9.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) HEAT_PBS PF03130.11 AEO56756.1 - 0.34 11.5 5.7 6.7 7.4 0.0 5.2 6 0 0 6 6 4 0 PBS lyase HEAT-like repeat N2227 PF07942.7 AEO56758.1 - 1.1e-96 322.9 0.0 1.4e-96 322.6 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 AEO56758.1 - 3.7e-09 36.4 0.0 6.1e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO56758.1 - 0.0021 18.4 0.0 0.018 15.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO56758.1 - 0.0075 16.7 0.0 0.016 15.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO56758.1 - 0.05 13.1 0.0 0.17 11.4 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.2 AEO56758.1 - 0.067 13.7 0.0 0.44 11.1 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 AEO56758.1 - 0.16 10.9 0.0 0.27 10.1 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family adh_short PF00106.20 AEO56759.1 - 1.5e-25 90.0 7.6 2.2e-25 89.4 5.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO56759.1 - 2.8e-22 79.6 0.0 4e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO56759.1 - 7e-16 58.4 3.3 1.1e-15 57.8 2.3 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 AEO56759.1 - 0.037 13.8 1.9 0.077 12.8 0.3 2.2 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase malic PF00390.14 AEO56759.1 - 0.13 11.8 0.0 2.3 7.7 0.0 2.2 2 0 0 2 2 2 0 Malic enzyme, N-terminal domain ubiquitin PF00240.18 AEO56760.1 - 4.7e-05 22.6 0.0 0.00012 21.3 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 AEO56760.1 - 0.00045 20.3 4.6 0.00045 20.3 3.2 2.4 3 1 0 3 3 3 1 DUF2407 ubiquitin-like domain PS_Dcarbxylase PF02666.10 AEO56761.1 - 2.2e-80 268.6 0.0 1.1e-79 266.4 0.0 1.8 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase NADH_oxidored PF08040.6 AEO56761.1 - 0.089 12.4 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 MNLL subunit Nitroreductase PF00881.19 AEO56762.1 - 2.7e-13 50.0 0.1 3.3e-13 49.8 0.1 1.0 1 0 0 1 1 1 1 Nitroreductase family DUF1983 PF09327.6 AEO56762.1 - 0.03 14.2 0.1 0.39 10.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1983) FAD_binding_1 PF00667.15 AEO56763.1 - 3.8e-45 154.0 0.0 5.3e-45 153.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 AEO56763.1 - 5.7e-10 39.7 0.0 1.6e-09 38.2 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain zf-rbx1 PF12678.2 AEO56767.1 - 9.8e-12 44.8 1.4 1.8e-11 43.9 1.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 AEO56767.1 - 1.9e-11 43.6 4.8 3.3e-11 42.8 3.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 AEO56767.1 - 2.9e-07 30.0 4.3 7.7e-07 28.6 3.1 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AEO56767.1 - 6.1e-06 25.8 3.2 1e-05 25.0 2.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO56767.1 - 7.2e-06 25.6 2.8 1.3e-05 24.7 1.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 AEO56767.1 - 1.8e-05 24.6 3.9 5.4e-05 23.1 2.7 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 AEO56767.1 - 0.0058 16.3 2.9 0.018 14.7 2.0 1.9 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.1 AEO56767.1 - 0.013 15.0 0.2 0.027 13.9 0.2 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 AEO56767.1 - 0.025 14.4 3.3 0.064 13.0 2.3 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 AEO56767.1 - 0.65 9.6 2.9 1.5 8.4 2.0 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 AEO56767.1 - 2.8 7.9 5.0 2.8 7.9 2.0 2.1 2 1 0 2 2 2 0 FANCL C-terminal domain CMD PF02627.15 AEO56768.1 - 4.9e-08 32.6 0.3 0.00037 20.2 0.0 3.0 2 1 0 2 2 2 2 Carboxymuconolactone decarboxylase family Methyltransf_16 PF10294.4 AEO56769.1 - 2.3e-08 33.7 0.0 3e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 AEO56769.1 - 0.0027 18.2 0.0 0.005 17.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain zf-C2H2_4 PF13894.1 AEO56770.1 - 0.00018 21.5 17.3 0.13 12.6 0.0 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 AEO56770.1 - 0.00024 21.2 21.1 0.73 10.3 1.1 4.7 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 AEO56770.1 - 0.0046 16.8 2.9 0.071 13.0 0.7 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger DUF629 PF04780.7 AEO56770.1 - 0.2 10.1 0.2 0.4 9.1 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF629) Dicty_REP PF05086.7 AEO56770.1 - 4.4 4.9 5.7 6.4 4.4 4.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein zf-H2C2_2 PF13465.1 AEO56770.1 - 10 6.6 20.6 1.2 9.5 0.7 4.3 4 1 0 4 4 4 0 Zinc-finger double domain Ribophorin_II PF05817.9 AEO56771.1 - 0.1 10.7 1.9 0.11 10.7 1.3 1.0 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit Ribophorin II Fibrillarin PF01269.12 AEO56773.1 - 2.1e-106 353.9 0.0 2.6e-106 353.6 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 AEO56773.1 - 5.6e-06 26.0 0.0 8.2e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 AEO56773.1 - 0.0047 16.4 0.1 0.0069 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 AEO56773.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_L22 PF00237.14 AEO56774.1 - 1.3e-34 118.2 0.1 1.9e-34 117.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Peptidase_C12 PF01088.16 AEO56775.1 - 1.2e-70 237.0 0.0 1.9e-70 236.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Xan_ur_permease PF00860.15 AEO56776.1 - 2.7e-27 95.2 28.5 4.2e-26 91.3 19.4 2.3 1 1 0 1 1 1 1 Permease family 7tm_2 PF00002.19 AEO56778.1 - 1e-11 44.4 3.5 1.7e-11 43.7 2.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.6 AEO56778.1 - 1.3e-11 44.0 7.5 1.3e-11 44.0 5.2 2.0 3 0 0 3 3 3 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.16 AEO56778.1 - 5.2e-09 35.6 0.1 8e-09 35.0 0.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.3 AEO56778.1 - 6.1e-08 32.4 9.2 1.2e-07 31.4 6.4 1.5 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Macoilin PF09726.4 AEO56778.1 - 0.13 10.5 0.9 0.15 10.2 0.6 1.2 1 0 0 1 1 1 0 Transmembrane protein Vps39_2 PF10367.4 AEO56779.1 - 6.7e-05 23.0 0.0 0.00015 21.8 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CASP_C PF08172.7 AEO56780.1 - 9.4e-90 299.9 0.2 9.4e-90 299.9 0.1 2.8 2 1 0 2 2 2 1 CASP C terminal Cast PF10174.4 AEO56780.1 - 0.00012 20.3 6.0 0.00012 20.3 4.2 3.2 3 0 0 3 3 3 2 RIM-binding protein of the cytomatrix active zone IncA PF04156.9 AEO56780.1 - 0.00084 18.9 59.1 0.036 13.6 3.0 5.3 3 1 2 5 5 5 2 IncA protein DUF3584 PF12128.3 AEO56780.1 - 0.0045 14.3 52.8 0.0088 13.4 12.0 4.0 3 1 0 4 4 4 4 Protein of unknown function (DUF3584) bZIP_2 PF07716.10 AEO56780.1 - 0.012 15.3 5.1 0.012 15.3 3.5 8.3 8 1 0 8 8 8 0 Basic region leucine zipper ATG16 PF08614.6 AEO56780.1 - 0.016 15.0 55.7 0.28 10.9 5.8 4.7 2 1 2 4 4 4 0 Autophagy protein 16 (ATG16) Tropomyosin_1 PF12718.2 AEO56780.1 - 0.074 12.8 62.9 0.022 14.5 16.1 5.3 4 1 1 5 5 5 0 Tropomyosin like FUSC PF04632.7 AEO56780.1 - 0.25 9.7 23.1 0.0083 14.6 1.0 3.4 3 0 0 3 3 3 0 Fusaric acid resistance protein family UPF0118 PF01594.11 AEO56780.1 - 0.29 10.0 1.7 0.69 8.8 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF20 Filament PF00038.16 AEO56780.1 - 0.37 10.2 52.4 3.4 7.0 9.3 3.7 2 1 1 3 3 3 0 Intermediate filament protein DivIVA PF05103.8 AEO56780.1 - 0.6 10.1 40.4 0.75 9.8 1.2 4.8 4 1 0 4 4 4 0 DivIVA protein GAS PF13851.1 AEO56780.1 - 1.6 7.9 54.4 1.1 8.3 0.9 5.5 5 1 0 5 5 5 0 Growth-arrest specific micro-tubule binding ADIP PF11559.3 AEO56780.1 - 2.8 7.8 64.1 0.22 11.4 4.6 6.7 4 1 3 7 7 7 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.4 AEO56780.1 - 6.7 6.5 63.6 0.046 13.5 1.5 5.7 3 1 2 5 5 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TBPIP PF07106.8 AEO56780.1 - 8.7 5.8 39.3 1.2 8.6 7.0 4.9 4 1 1 5 5 5 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3455 PF11937.3 AEO56781.1 - 1.5e-30 106.4 0.0 1.9e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2990 PF11693.3 AEO56781.1 - 4.6 7.1 7.0 0.47 10.3 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2990) NIF PF03031.13 AEO56782.1 - 5.8e-18 65.0 0.0 7.6e-18 64.6 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DDE_Tnp_ISL3 PF01610.12 AEO56782.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 Transposase EF1G PF00647.14 AEO56783.1 - 1.6e-44 149.9 0.3 2.8e-44 149.2 0.2 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 AEO56783.1 - 1.7e-14 53.5 0.0 4.3e-14 52.2 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 AEO56783.1 - 9.6e-13 48.1 0.0 4.3e-12 46.0 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 AEO56783.1 - 1.1e-11 44.4 0.0 4.5e-11 42.4 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 AEO56783.1 - 3.6e-10 39.9 0.0 8.4e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 AEO56783.1 - 2e-06 28.2 0.0 3.9e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 AEO56783.1 - 8.1e-05 22.5 0.0 0.0002 21.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 AEO56783.1 - 0.031 14.2 0.0 0.55 10.2 0.0 2.4 2 0 0 2 2 2 0 Glutaredoxin Ribosomal_S9 PF00380.14 AEO56784.1 - 1.2e-37 128.8 0.9 2.3e-37 127.8 0.6 1.5 1 0 0 1 1 1 1 Ribosomal protein S9/S16 HTH_AraC PF00165.18 AEO56784.1 - 0.071 12.9 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family EF-hand_1 PF00036.27 AEO56786.1 - 2.7e-27 91.9 10.7 1.7e-07 29.9 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 AEO56786.1 - 6.3e-24 83.8 2.1 1.2e-12 47.7 0.3 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 AEO56786.1 - 7.7e-21 72.0 5.7 4.7e-05 22.9 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 AEO56786.1 - 4.1e-19 66.9 11.5 1.6e-06 27.1 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 AEO56786.1 - 2.1e-15 56.0 11.8 2.3e-05 23.9 0.5 4.6 1 1 3 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 AEO56786.1 - 7.8e-07 29.1 0.0 0.00081 19.4 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 AEO56786.1 - 7.9e-06 25.5 7.7 0.011 15.5 0.3 3.9 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 AEO56786.1 - 0.0078 16.1 0.1 0.17 11.8 0.0 2.7 2 1 1 3 3 3 1 EF-hand domain EPL1 PF10513.4 AEO56787.1 - 4.7e-30 104.9 4.7 4.7e-30 104.9 3.3 3.5 2 1 1 3 3 3 1 Enhancer of polycomb-like GARS_A PF01071.14 AEO56787.1 - 0.068 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Peptidase_M22 PF00814.20 AEO56789.1 - 7.8e-84 281.3 0.0 9.2e-84 281.0 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Staygreen PF12638.2 AEO56789.1 - 0.087 12.3 0.0 0.77 9.2 0.0 2.0 2 0 0 2 2 2 0 Staygreen protein AMPKBI PF04739.10 AEO56790.1 - 1.3e-30 105.1 1.9 1.3e-30 105.1 1.3 1.9 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain Spt4 PF06093.8 AEO56791.1 - 4.5e-33 112.9 0.1 5.5e-33 112.6 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger TBCC PF07986.7 AEO56791.1 - 0.037 13.4 0.1 0.046 13.1 0.0 1.1 1 0 0 1 1 1 0 Tubulin binding cofactor C Kin17_mid PF10357.4 AEO56792.1 - 1.6e-47 160.3 2.5 1.6e-47 160.3 1.7 1.6 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.2 AEO56792.1 - 4.3e-05 23.5 4.9 7.1e-05 22.8 3.4 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 AEO56792.1 - 0.00035 20.6 5.6 0.00064 19.7 3.9 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding DUF4325 PF14213.1 AEO56792.1 - 0.00069 19.2 0.1 0.12 12.0 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4325) zf-C2H2_2 PF12756.2 AEO56792.1 - 0.00093 19.2 1.6 0.0019 18.2 1.1 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 AEO56792.1 - 1.9 9.0 3.8 3.9 8.0 2.6 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger AA_kinase PF00696.23 AEO56793.1 - 3.6e-37 128.2 0.0 6.1e-37 127.4 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.20 AEO56793.1 - 1.1e-16 59.9 1.2 8.2e-10 37.9 0.0 2.7 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.1 AEO56793.1 - 2e-14 52.8 3.6 1.8e-10 40.1 0.1 2.5 2 0 0 2 2 2 2 ACT domain adh_short PF00106.20 AEO56793.1 - 0.027 14.4 0.6 0.056 13.3 0.4 1.5 1 0 0 1 1 1 0 short chain dehydrogenase ABC_membrane PF00664.18 AEO56794.1 - 1.2e-47 162.6 12.0 1.6e-47 162.2 8.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 AEO56794.1 - 4.1e-34 117.8 0.0 1.3e-33 116.1 0.0 1.9 2 0 0 2 2 1 1 ABC transporter SMC_N PF02463.14 AEO56794.1 - 2.3e-05 23.7 0.0 0.00086 18.5 0.0 2.3 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 AEO56794.1 - 8.7e-05 22.5 0.1 0.00028 20.9 0.0 1.9 2 0 0 2 2 1 1 AAA ATPase domain AAA_17 PF13207.1 AEO56794.1 - 0.0014 19.4 1.0 0.0048 17.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 AEO56794.1 - 0.0017 18.5 0.3 0.034 14.3 0.2 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 AEO56794.1 - 0.0047 16.6 0.1 0.022 14.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 AEO56794.1 - 0.0068 15.9 0.0 0.019 14.4 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 AEO56794.1 - 0.0096 16.0 0.1 0.056 13.5 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.1 AEO56794.1 - 0.01 15.7 6.9 0.67 9.8 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_23 PF13476.1 AEO56794.1 - 0.034 14.4 7.2 2.2 8.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 AEO56794.1 - 0.037 13.9 1.1 0.41 10.5 0.7 2.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.4 AEO56794.1 - 0.049 12.2 0.3 0.12 10.9 0.1 1.6 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_10 PF12846.2 AEO56794.1 - 0.056 12.8 0.9 0.22 10.9 0.2 2.0 2 0 0 2 2 2 0 AAA-like domain IstB_IS21 PF01695.12 AEO56794.1 - 0.09 12.1 0.1 0.25 10.7 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 AEO56794.1 - 0.093 12.7 0.0 0.67 10.0 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.1 AEO56794.1 - 0.13 11.6 1.1 0.71 9.2 0.8 2.0 1 1 0 1 1 1 0 AAA domain PrgI PF12666.2 AEO56794.1 - 5.3 7.2 9.7 0.85 9.8 0.1 3.1 3 0 0 3 3 3 0 PrgI family protein CTD_bind PF04818.8 AEO56795.1 - 1.5e-21 76.3 0.1 4.7e-21 74.8 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase II-binding domain. CTK3 PF12243.3 AEO56795.1 - 0.0075 15.9 0.1 0.018 14.6 0.0 1.6 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 Clathrin_lg_ch PF01086.12 AEO56796.1 - 1.6e-76 257.1 4.6 1.8e-76 256.9 3.2 1.0 1 0 0 1 1 1 1 Clathrin light chain ATP-synt_B PF00430.13 AEO56796.1 - 0.8 9.5 7.3 1.4 8.7 5.1 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) SNARE PF05739.14 AEO56797.1 - 1.5e-18 66.2 7.0 1.5e-18 66.2 2.9 2.3 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 AEO56797.1 - 5.6e-14 52.1 7.1 4e-13 49.4 0.1 2.6 2 1 0 2 2 2 1 Syntaxin MCPsignal PF00015.16 AEO56797.1 - 0.0015 18.1 8.5 0.016 14.7 0.8 2.7 2 1 0 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin_2 PF14523.1 AEO56797.1 - 0.0041 17.1 9.4 0.48 10.4 0.6 3.1 2 1 1 3 3 3 3 Syntaxin-like protein Arc_PepC PF06819.6 AEO56797.1 - 0.45 10.4 5.3 1.3 8.9 0.9 2.8 2 1 1 3 3 3 0 Archaeal Peptidase A24 C-terminal Domain SlyX PF04102.7 AEO56797.1 - 2.3 8.6 7.7 1 9.7 1.0 3.2 2 2 2 4 4 4 0 SlyX H-kinase_dim PF02895.9 AEO56797.1 - 3.5 8.0 6.1 3 8.2 0.8 2.8 2 2 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain ATG16 PF08614.6 AEO56797.1 - 4.5 7.0 12.4 1.2 8.9 1.1 2.9 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) EF-hand_1 PF00036.27 AEO56798.1 - 2.8e-41 135.6 12.8 1.1e-09 36.9 0.6 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 AEO56798.1 - 1.7e-36 124.1 5.8 6.4e-20 71.0 1.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 AEO56798.1 - 8.5e-35 118.1 12.2 6.8e-16 57.6 0.5 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 AEO56798.1 - 1.2e-30 102.6 8.0 1.2e-09 37.2 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 AEO56798.1 - 5.2e-26 88.7 9.7 1.4e-06 27.3 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 AEO56798.1 - 1.3e-15 57.0 0.3 2.2e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 AEO56798.1 - 2.6e-09 36.7 1.9 0.00056 19.6 0.2 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 AEO56798.1 - 1.5e-08 34.6 0.1 0.0038 17.2 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 AEO56798.1 - 3.2e-08 33.0 0.1 0.022 14.3 0.0 3.3 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 AEO56798.1 - 4.4e-07 29.7 2.1 4.5e-06 26.5 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.8 AEO56798.1 - 0.00014 21.5 0.3 0.32 10.7 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.8 AEO56798.1 - 0.00023 20.7 0.2 0.075 12.5 0.0 2.7 1 1 1 3 3 3 1 Caleosin related protein Tenui_NCP PF04876.7 AEO56798.1 - 0.0025 17.3 0.1 0.13 11.8 0.0 2.3 1 1 1 2 2 2 1 Tenuivirus major non-capsid protein RNA_pol_Rpb4 PF03874.11 AEO56798.1 - 0.0026 17.7 0.7 1.3 9.0 0.0 2.6 3 0 0 3 3 3 2 RNA polymerase Rpb4 Toprim_2 PF13155.1 AEO56798.1 - 0.0083 16.4 1.3 2.5 8.4 0.0 2.5 1 1 2 3 3 3 2 Toprim-like DUF3349 PF11829.3 AEO56798.1 - 0.021 15.2 0.4 12 6.4 0.0 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) EF-hand_10 PF14788.1 AEO56798.1 - 0.14 11.8 2.5 0.83 9.3 0.1 3.1 1 1 3 4 4 4 0 EF hand RloB PF13707.1 AEO56798.1 - 0.38 10.3 4.1 0.99 9.0 1.1 2.2 1 1 0 2 2 2 0 RloB-like protein PB1 PF00564.19 AEO56798.1 - 0.45 10.2 2.8 35 4.1 0.0 3.3 2 1 1 3 3 3 0 PB1 domain Adaptin_N PF01602.15 AEO56799.1 - 7.8e-142 473.2 3.3 9.3e-142 473.0 2.3 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 AEO56799.1 - 5.7e-19 68.5 0.0 1.4e-18 67.3 0.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 AEO56799.1 - 1.6e-06 28.3 2.8 0.17 12.1 0.1 4.4 3 3 0 3 3 3 2 HEAT repeats Cnd1 PF12717.2 AEO56799.1 - 0.00052 19.9 6.3 0.0026 17.6 0.2 3.2 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 AEO56799.1 - 0.0016 18.3 1.9 13 6.1 0.0 5.1 4 1 1 5 5 5 1 HEAT repeat Arm PF00514.18 AEO56799.1 - 0.013 15.2 0.1 56 3.7 0.1 5.1 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat G-patch_2 PF12656.2 AEO56799.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 DExH-box splicing factor binding site TIP120 PF08623.5 AEO56799.1 - 0.16 11.5 0.1 0.16 11.5 0.1 2.6 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) DUF947 PF06102.7 AEO56800.1 - 4.5e-55 186.0 26.0 4.5e-55 186.0 18.0 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF947) HHA PF05321.6 AEO56800.1 - 4.9 7.3 7.4 7.6 6.7 0.1 2.6 2 0 0 2 2 2 0 Haemolysin expression modulating protein DUF4613 PF15390.1 AEO56800.1 - 5.4 5.0 6.7 10 4.1 4.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) ABC1 PF03109.11 AEO56801.1 - 6.5e-32 110.0 0.0 1.5e-31 108.8 0.0 1.6 1 0 0 1 1 1 1 ABC1 family Es2 PF09751.4 AEO56802.1 - 1.8e-98 330.7 0.1 2.2e-98 330.4 0.0 1.1 1 0 0 1 1 1 1 Nuclear protein Es2 Hus1 PF04005.7 AEO56803.1 - 4.8e-87 291.5 0.0 6.5e-87 291.1 0.0 1.1 1 0 0 1 1 1 1 Hus1-like protein zf-RING_2 PF13639.1 AEO56803.1 - 7.2e-08 32.1 1.6 1.5e-07 31.0 1.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 AEO56803.1 - 2.7e-06 26.9 1.3 6e-06 25.8 0.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 AEO56803.1 - 3e-05 24.0 0.2 7.8e-05 22.7 0.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 AEO56803.1 - 8.2e-05 22.1 1.4 8.2e-05 22.1 0.9 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO56803.1 - 0.00016 21.3 1.7 0.00036 20.1 1.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 AEO56803.1 - 0.00026 20.9 1.1 0.00026 20.9 0.7 1.9 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 AEO56803.1 - 0.004 17.0 0.5 0.0097 15.7 0.3 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 AEO56803.1 - 0.015 15.1 0.6 0.042 13.6 0.3 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 AEO56803.1 - 0.56 9.8 2.8 1.5 8.4 1.9 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 AEO56803.1 - 0.63 9.8 4.6 0.71 9.6 0.1 2.5 2 0 0 2 2 2 0 RING-type zinc-finger Sec16_C PF12931.2 AEO56804.1 - 6.5e-93 311.5 0.0 8.6e-93 311.1 0.0 1.1 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 AEO56804.1 - 1.4e-32 112.0 0.0 2.8e-32 111.1 0.0 1.5 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Sec16_N PF12935.2 AEO56804.1 - 2.9e-12 47.0 24.5 2.9e-12 47.0 17.0 4.1 3 1 0 4 4 4 1 Vesicle coat trafficking protein Sec16 N-terminus Hydrolase PF00702.21 AEO56805.1 - 6e-16 59.5 0.0 1.8e-15 57.9 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 AEO56805.1 - 2.6e-14 52.8 0.0 6e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 AEO56805.1 - 1.3e-10 41.7 0.0 3.1e-10 40.5 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AEO56805.1 - 0.00096 19.0 0.0 0.0033 17.3 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 AEO56805.1 - 0.0041 16.7 0.0 0.0082 15.7 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase FAD_binding_6 PF00970.19 AEO56806.1 - 3.8e-07 30.1 0.0 2.6e-06 27.4 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 AEO56806.1 - 5.8e-05 23.6 0.0 0.00011 22.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain 4HBT_3 PF13622.1 AEO56806.1 - 0.061 13.0 20.5 0.7 9.5 3.3 2.5 1 1 1 2 2 2 0 Thioesterase-like superfamily Suc_Fer-like PF06999.7 AEO56807.1 - 3.3e-56 190.8 0.0 4e-56 190.6 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like tRNA-synt_1 PF00133.17 AEO56808.1 - 4.1e-49 167.1 0.0 2.5e-16 58.8 0.0 6.0 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 AEO56808.1 - 2.2e-40 137.9 0.0 8.1e-40 136.0 0.0 2.0 1 1 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 AEO56808.1 - 1.7e-29 102.7 0.0 1.5e-21 76.4 0.0 4.3 3 1 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 AEO56808.1 - 1.4e-13 50.9 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1d PF00750.14 AEO56808.1 - 0.071 11.9 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (R) AA_permease_2 PF13520.1 AEO56809.1 - 1.1e-63 215.3 35.1 1.7e-63 214.6 24.3 1.3 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 AEO56809.1 - 4.1e-30 104.5 23.4 4.1e-30 104.5 16.2 1.7 2 0 0 2 2 2 1 Amino acid permease 2-Hacid_dh_C PF02826.14 AEO56810.1 - 2.4e-51 173.3 0.0 3.6e-51 172.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 AEO56810.1 - 8.1e-16 57.7 0.0 1.1e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain DUF3684 PF12449.3 AEO56811.1 - 0 1426.1 0.0 0 1425.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.1 AEO56811.1 - 1.3e-06 28.0 0.0 3.1e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Reprolysin_5 PF13688.1 AEO56811.1 - 0.0034 17.3 0.2 0.0085 16.0 0.2 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 MMtag PF10159.4 AEO56812.1 - 4.8e-30 103.4 1.8 4.8e-30 103.4 1.2 3.1 2 1 1 3 3 3 1 Kinase phosphorylation protein Med6 PF04934.9 AEO56813.1 - 2e-35 121.3 0.0 2.4e-35 121.1 0.0 1.0 1 0 0 1 1 1 1 MED6 mediator sub complex component HA2 PF04408.18 AEO56814.1 - 1.4e-18 66.8 0.0 4e-18 65.3 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 AEO56814.1 - 1.1e-13 50.9 0.0 2.9e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 AEO56814.1 - 1.8e-13 50.1 0.0 6.2e-13 48.4 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 AEO56814.1 - 1.3e-08 34.5 0.1 1.2e-07 31.3 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 AEO56814.1 - 0.00066 19.8 0.1 0.0049 17.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 AEO56814.1 - 0.0014 18.4 1.7 0.47 10.2 0.0 3.7 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit T2SE PF00437.15 AEO56814.1 - 0.02 13.7 0.0 0.041 12.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.11 AEO56814.1 - 0.027 13.7 0.3 0.058 12.6 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein KaiC PF06745.8 AEO56814.1 - 0.063 12.3 0.0 0.17 10.9 0.0 1.6 1 0 0 1 1 1 0 KaiC Ribosomal_L18e PF00828.14 AEO56816.1 - 1.3e-32 112.8 0.0 1.8e-32 112.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Metallophos PF00149.23 AEO56817.1 - 2.4e-42 144.6 1.4 3.9e-42 143.9 1.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase adh_short_C2 PF13561.1 AEO56818.1 - 1.5e-24 87.1 0.0 2e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 AEO56818.1 - 1.3e-22 80.4 2.4 3.2e-22 79.2 1.6 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO56818.1 - 3.9e-08 33.1 1.4 7.4e-08 32.2 0.1 1.8 2 0 0 2 2 2 1 KR domain PALP PF00291.20 AEO56818.1 - 0.0011 18.2 0.7 0.0015 17.7 0.5 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme 2-Hacid_dh_C PF02826.14 AEO56818.1 - 0.0025 17.0 0.0 0.0038 16.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 AEO56818.1 - 0.0034 17.0 0.5 0.0069 16.0 0.3 1.5 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 AEO56818.1 - 0.0063 16.9 0.5 0.012 16.0 0.4 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.1 AEO56818.1 - 0.0067 16.6 0.2 0.014 15.6 0.1 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 AEO56818.1 - 0.02 14.6 0.2 0.039 13.6 0.2 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AdoHcyase_NAD PF00670.16 AEO56818.1 - 0.047 13.5 0.1 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DFP PF04127.10 AEO56818.1 - 0.073 12.6 0.4 0.14 11.7 0.3 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Pyr_redox PF00070.22 AEO56818.1 - 0.13 12.6 0.3 0.37 11.2 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PhoD PF09423.5 AEO56819.1 - 7.9e-65 219.1 0.0 1e-64 218.8 0.0 1.2 1 0 0 1 1 1 1 PhoD-like phosphatase TauD PF02668.11 AEO56819.1 - 5.7e-39 134.3 0.2 8.6e-39 133.7 0.1 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family GerA PF03323.8 AEO56819.1 - 0.57 8.2 0.0 0.85 7.6 0.0 1.1 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein EMP24_GP25L PF01105.19 AEO56820.1 - 4.7e-48 163.3 0.9 5.4e-48 163.1 0.6 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SKIP_SNW PF02731.10 AEO56821.1 - 3.7e-67 224.7 6.5 3.7e-67 224.7 4.5 2.6 3 0 0 3 3 3 1 SKIP/SNW domain DUF4603 PF15376.1 AEO56821.1 - 0.27 8.3 10.5 0.38 7.8 7.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Glyco_hydro_16 PF00722.16 AEO56822.1 - 4.2e-08 32.6 0.0 9.7e-08 31.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SP_C-Propep PF08999.5 AEO56822.1 - 0.015 14.7 0.6 0.027 13.9 0.4 1.4 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide VirB8 PF04335.8 AEO56822.1 - 3.2 7.2 5.3 3.5 7.1 1.5 2.0 2 0 0 2 2 2 0 VirB8 protein Tim17 PF02466.14 AEO56823.1 - 1.5e-49 167.2 10.9 1.5e-49 167.2 7.6 1.9 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family DUF543 PF04418.7 AEO56823.1 - 0.027 14.3 0.4 1.2 9.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF543) USP7_ICP0_bdg PF12436.3 AEO56824.1 - 2.6e-87 292.1 0.3 2.3e-85 285.8 0.1 2.7 2 1 1 3 3 3 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 AEO56824.1 - 4.1e-73 245.3 3.3 1e-69 234.2 0.0 4.0 4 0 0 4 4 4 2 Ubiquitin-specific protease C-terminal UCH PF00443.24 AEO56824.1 - 1.9e-56 191.1 2.4 1.9e-56 191.1 1.7 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AEO56824.1 - 3.5e-30 105.4 0.3 6.3e-30 104.6 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 AEO56824.1 - 2.6e-12 47.0 1.4 1.4e-11 44.6 0.1 2.9 4 0 0 4 4 4 1 MATH domain YukD PF08817.5 AEO56824.1 - 0.1 13.1 0.0 2.8 8.5 0.0 3.3 4 0 0 4 4 4 0 WXG100 protein secretion system (Wss), protein YukD BCDHK_Adom3 PF10436.4 AEO56825.1 - 5.4e-46 156.0 0.1 1e-45 155.1 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 AEO56825.1 - 1.9e-10 40.4 0.1 1.1e-08 34.8 0.1 2.4 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 AEO56825.1 - 0.00036 20.1 0.0 0.0007 19.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 AEO56825.1 - 0.025 14.3 0.1 0.6 9.9 0.0 2.8 2 1 0 2 2 2 0 Histidine kinase-like ATPase domain Septin PF00735.13 AEO56826.1 - 2.1e-117 391.1 0.5 3.2e-117 390.5 0.4 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 AEO56826.1 - 7.5e-07 29.1 0.0 1.4e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 AEO56826.1 - 1.8e-06 27.4 0.4 4.9e-05 22.8 0.1 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 AEO56826.1 - 1.4e-05 24.3 0.0 4.1e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 AEO56826.1 - 0.0025 18.3 0.1 0.0089 16.5 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein AAA_24 PF13479.1 AEO56826.1 - 0.0034 17.0 0.1 0.0068 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 AEO56826.1 - 0.005 16.3 0.0 0.015 14.8 0.0 1.8 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_22 PF13401.1 AEO56826.1 - 0.0051 16.9 0.1 0.019 15.1 0.0 2.1 2 1 0 2 2 2 1 AAA domain IIGP PF05049.8 AEO56826.1 - 0.0077 15.0 0.0 0.014 14.2 0.0 1.5 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AIG1 PF04548.11 AEO56826.1 - 0.01 14.9 0.0 0.023 13.8 0.0 1.6 1 0 0 1 1 1 0 AIG1 family Pox_A32 PF04665.7 AEO56826.1 - 0.012 14.9 0.1 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein Ras PF00071.17 AEO56826.1 - 0.018 14.3 0.6 0.058 12.7 0.3 1.9 2 1 0 2 2 2 0 Ras family ABC_tran PF00005.22 AEO56826.1 - 0.032 14.5 0.2 0.15 12.4 0.0 2.1 2 0 0 2 2 2 0 ABC transporter T2SE PF00437.15 AEO56826.1 - 0.034 13.0 0.5 0.094 11.6 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein ArgK PF03308.11 AEO56826.1 - 0.036 12.8 2.4 0.95 8.1 0.0 3.0 3 0 0 3 3 3 0 ArgK protein NACHT PF05729.7 AEO56826.1 - 0.041 13.5 0.0 0.077 12.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 AEO56826.1 - 0.041 13.8 2.8 0.63 10.0 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain Sigma54_activat PF00158.21 AEO56826.1 - 0.073 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF2968 PF11180.3 AEO56826.1 - 0.079 12.3 7.3 0.23 10.8 5.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Dynamin_N PF00350.18 AEO56826.1 - 0.079 12.7 7.6 0.67 9.7 0.1 3.1 2 1 1 3 3 3 0 Dynamin family PduV-EutP PF10662.4 AEO56826.1 - 0.089 12.2 1.1 2.6 7.5 0.2 2.7 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 AEO56826.1 - 0.14 12.3 0.0 0.37 10.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Ribosomal_L6e PF01159.14 AEO56826.1 - 0.24 11.6 5.0 5.8 7.2 0.1 3.3 3 0 0 3 3 3 0 Ribosomal protein L6e ATP_bind_1 PF03029.12 AEO56826.1 - 0.26 10.7 1.1 9.6 5.6 0.1 2.6 2 1 0 3 3 3 0 Conserved hypothetical ATP binding protein KAP_NTPase PF07693.9 AEO56826.1 - 0.29 10.0 3.6 0.63 8.9 2.5 1.7 1 1 0 1 1 1 0 KAP family P-loop domain Atg14 PF10186.4 AEO56826.1 - 0.39 9.6 7.8 0.91 8.4 5.4 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Seryl_tRNA_N PF02403.17 AEO56826.1 - 1.3 9.0 8.6 0.59 10.1 2.8 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.10 AEO56826.1 - 4.5 6.8 9.5 0.98 8.9 3.1 2.4 2 0 0 2 2 2 0 Septum formation initiator Myc-LZ PF02344.10 AEO56826.1 - 6 6.5 12.8 5.4 6.7 4.5 3.0 2 1 0 2 2 2 0 Myc leucine zipper domain AAA_23 PF13476.1 AEO56826.1 - 6.6 6.9 21.5 1.4e+02 2.6 14.9 2.2 1 1 0 1 1 1 0 AAA domain WD40 PF00400.27 AEO56827.1 - 1.1e-50 167.8 30.6 8.1e-12 44.5 0.0 12.0 12 0 0 12 12 12 9 WD domain, G-beta repeat Utp12 PF04003.7 AEO56827.1 - 4.3e-26 90.9 0.0 6.7e-26 90.3 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 AEO56827.1 - 3.1e-05 23.7 2.1 0.19 11.4 0.0 5.8 5 1 2 8 8 8 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 AEO56827.1 - 0.0031 15.7 1.0 0.17 10.0 0.0 3.5 1 1 2 3 3 3 1 Nucleoporin Nup120/160 Nbas_N PF15492.1 AEO56827.1 - 0.0048 16.0 0.3 9.3 5.2 0.0 4.1 3 2 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.7 AEO56827.1 - 0.0053 14.6 0.0 0.15 9.8 0.0 2.5 2 1 0 2 2 2 1 IKI3 family Utp13 PF08625.6 AEO56827.1 - 0.16 11.6 0.1 0.45 10.1 0.1 1.9 1 1 0 1 1 1 0 Utp13 specific WD40 associated domain DUF4243 PF14027.1 AEO56828.1 - 1.9e-88 297.1 0.6 2.3e-88 296.8 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Exo_endo_phos PF03372.18 AEO56829.1 - 1.1e-27 97.5 0.2 1.9e-27 96.8 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PEHE PF15275.1 AEO56830.1 - 0.087 13.2 0.3 0.11 12.9 0.2 1.1 1 0 0 1 1 1 0 PEHE domain Planc_extracel PF07595.7 AEO56830.1 - 0.1 12.2 0.8 0.29 10.8 0.6 1.8 1 0 0 1 1 1 0 Planctomycete extracellular CTD_bind PF04818.8 AEO56831.1 - 2.5e-09 37.2 0.0 5.5e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. B56 PF01603.15 AEO56832.1 - 5.1e-173 575.3 5.8 6.1e-173 575.1 4.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Dynamin_N PF00350.18 AEO56832.1 - 0.14 11.9 0.0 0.39 10.5 0.0 1.7 1 0 0 1 1 1 0 Dynamin family Tau95 PF09734.4 AEO56833.1 - 2.7e-41 141.9 0.0 4.7e-41 141.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit BCS1_N PF08740.6 AEO56834.1 - 1.7e-42 145.1 0.0 1.7e-42 145.1 0.0 2.0 3 0 0 3 3 2 1 BCS1 N terminal AAA PF00004.24 AEO56834.1 - 3.7e-16 59.5 0.0 3.7e-07 30.4 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) SR-25 PF10500.4 AEO56834.1 - 0.00081 18.9 10.8 0.00081 18.9 7.5 2.4 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein AAA_17 PF13207.1 AEO56834.1 - 0.00087 20.0 0.0 0.0022 18.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 AEO56834.1 - 0.0013 17.8 0.0 0.003 16.6 0.0 1.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 AEO56834.1 - 0.0031 16.9 0.0 0.0071 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain Apt1 PF10351.4 AEO56834.1 - 0.0051 15.7 0.1 0.0073 15.2 0.1 1.4 1 0 0 1 1 1 1 Golgi-body localisation protein domain AAA_11 PF13086.1 AEO56834.1 - 0.0069 15.9 0.0 0.017 14.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 AEO56834.1 - 0.017 14.8 0.0 0.053 13.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) KaiC PF06745.8 AEO56834.1 - 0.17 10.9 0.0 0.3 10.1 0.0 1.3 1 0 0 1 1 1 0 KaiC DUF4614 PF15391.1 AEO56834.1 - 7 6.3 12.3 2.7 7.7 3.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) SSP160 PF06933.6 AEO56835.1 - 0.35 8.7 25.8 0.43 8.4 17.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Med3 PF11593.3 AEO56835.1 - 0.5 9.5 9.6 0.41 9.8 6.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Sporozoite_P67 PF05642.6 AEO56835.1 - 0.89 7.3 5.8 0.73 7.6 4.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Asparaginase PF00710.15 AEO56836.1 - 3.3e-101 338.2 0.0 4.2e-101 337.9 0.0 1.1 1 0 0 1 1 1 1 Asparaginase Ank_2 PF12796.2 AEO56836.1 - 2.7e-11 43.6 0.1 9.9e-11 41.8 0.1 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 AEO56836.1 - 3.3e-10 39.2 0.1 0.00025 20.6 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 AEO56836.1 - 1.1e-08 35.3 0.1 0.0039 17.6 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 AEO56836.1 - 1e-06 28.7 0.5 0.00088 19.4 0.1 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 AEO56836.1 - 0.00028 20.8 0.1 4.9 7.7 0.0 3.9 3 0 0 3 3 3 1 Ankyrin repeat NAP PF00956.13 AEO56837.1 - 1.4e-53 181.5 3.7 1.4e-53 181.5 2.6 2.0 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) BUD22 PF09073.5 AEO56837.1 - 0.46 9.5 18.9 0.64 9.0 13.1 1.2 1 0 0 1 1 1 0 BUD22 Nucleoplasmin PF03066.10 AEO56837.1 - 4.8 6.6 29.7 2.7 7.4 6.1 3.0 3 0 0 3 3 3 0 Nucleoplasmin Glyco_hydro_76 PF03663.9 AEO56838.1 - 5.5e-155 516.3 3.1 6.6e-155 516.0 2.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 AEO56838.1 - 0.0054 15.8 5.8 0.49 9.3 0.1 3.1 2 1 1 3 3 3 3 Glycosyl Hydrolase Family 88 Dak1 PF02733.12 AEO56839.1 - 9e-107 356.3 12.9 6.1e-106 353.6 8.9 1.9 1 1 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 AEO56839.1 - 1.3e-44 151.9 0.1 3.1e-44 150.7 0.0 1.7 1 0 0 1 1 1 1 DAK2 domain ECH_C PF13766.1 AEO56840.1 - 1.3e-35 122.1 0.1 3.1e-35 120.8 0.1 1.6 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 AEO56840.1 - 1.2e-25 90.0 0.0 2.6e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family CTP_transf_1 PF01148.15 AEO56841.1 - 0.0014 18.3 18.7 0.005 16.5 7.2 3.2 3 1 0 3 3 3 1 Cytidylyltransferase family Cortexin PF11057.3 AEO56841.1 - 0.053 13.1 0.2 13 5.5 0.0 2.6 2 0 0 2 2 2 0 Cortexin of kidney HTH_psq PF05225.11 AEO56843.1 - 7e-11 41.5 0.2 1e-10 40.9 0.1 1.3 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_23 PF13384.1 AEO56843.1 - 0.0035 16.9 0.0 0.0052 16.3 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 AEO56843.1 - 0.0055 16.6 0.0 0.0094 15.9 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_17 PF12728.2 AEO56843.1 - 0.0095 16.1 0.0 0.013 15.6 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain NUMOD1 PF07453.8 AEO56843.1 - 0.023 14.5 0.1 0.13 12.1 0.0 2.1 2 0 0 2 2 2 0 NUMOD1 domain SpoIIID PF12116.3 AEO56843.1 - 0.046 13.6 0.1 0.062 13.2 0.1 1.3 1 0 0 1 1 1 0 Stage III sporulation protein D MerR PF00376.18 AEO56843.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 MerR family regulatory protein DUF1754 PF08555.5 AEO56844.1 - 8.1e-14 52.0 10.9 2e-13 50.7 7.5 1.7 1 1 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) DUF1978 PF09321.5 AEO56844.1 - 0.027 13.9 1.4 0.041 13.3 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) cobW PF02492.14 AEO56846.1 - 2.9e-35 121.3 0.0 4.4e-35 120.7 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 AEO56846.1 - 0.006 16.2 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 AEO56846.1 - 0.006 16.3 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 AEO56846.1 - 0.022 14.2 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AA_permease PF00324.16 AEO56847.1 - 5.3e-61 206.4 28.0 7.3e-61 205.9 19.4 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AEO56847.1 - 3.2e-15 55.6 34.2 4.9e-15 55.0 23.7 1.2 1 0 0 1 1 1 1 Amino acid permease Aa_trans PF01490.13 AEO56848.1 - 1.3e-81 274.1 30.9 1.6e-81 273.9 21.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein RNA_pol_L_2 PF13656.1 AEO56849.1 - 1.3e-19 69.3 0.0 1.5e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 AEO56849.1 - 2.7e-07 29.6 0.0 4e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain LSM PF01423.17 AEO56850.1 - 8.3e-21 73.3 0.1 9.3e-21 73.1 0.1 1.0 1 0 0 1 1 1 1 LSM domain DNA_pol_A_exo1 PF01612.15 AEO56851.1 - 1.1e-18 67.3 0.0 1.5e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease WD40 PF00400.27 AEO56852.1 - 5.9e-29 98.8 12.9 1.5e-07 31.0 0.2 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat NLE PF08154.7 AEO56852.1 - 7.9e-20 70.6 0.1 1.3e-19 69.9 0.1 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain DNA_pol_E_B PF04042.11 AEO56853.1 - 3.1e-53 180.1 0.0 4e-53 179.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DUF3245 PF11595.3 AEO56854.1 - 0.24 11.6 2.4 0.28 11.4 0.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) PALP PF00291.20 AEO56855.1 - 1.7e-58 198.2 1.1 2.3e-58 197.8 0.7 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Acetyltransf_3 PF13302.1 AEO56856.1 - 2.7e-24 85.9 0.0 3.3e-24 85.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 AEO56856.1 - 8.6e-08 32.2 1.7 4.7e-05 23.3 1.2 3.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 AEO56856.1 - 8.9e-07 28.5 0.0 0.016 14.9 0.0 2.4 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_1 PF00583.19 AEO56856.1 - 1.2e-05 25.2 0.1 6e-05 23.0 0.1 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 AEO56856.1 - 0.0077 16.1 0.0 0.062 13.2 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 AEO56856.1 - 0.018 15.1 0.0 0.036 14.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain tRNA-synt_1g PF09334.6 AEO56857.1 - 6.1e-118 393.8 0.4 9.4e-118 393.2 0.2 1.3 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 AEO56857.1 - 4.4e-24 84.4 4.6 1e-10 40.2 0.0 4.0 1 1 2 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 AEO56857.1 - 8.5e-08 31.6 0.1 0.0057 15.8 0.1 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Peripla_BP_3 PF13377.1 AEO56857.1 - 0.05 13.5 0.4 7.9 6.4 0.0 2.6 1 1 1 2 2 2 0 Periplasmic binding protein-like domain Rota_VP2 PF05087.7 AEO56858.1 - 0.12 10.2 0.0 0.18 9.7 0.0 1.1 1 0 0 1 1 1 0 Rotavirus VP2 protein ZZ PF00569.12 AEO56858.1 - 3.4 7.2 8.7 0.55 9.8 0.1 3.0 4 0 0 4 4 4 0 Zinc finger, ZZ type Glyco_hydro_28 PF00295.12 AEO56859.1 - 1.3e-33 116.3 5.6 1.7e-33 115.9 3.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pkinase PF00069.20 AEO56860.1 - 2.8e-19 69.3 0.0 2.1e-18 66.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO56860.1 - 1.5e-07 30.7 0.0 1.1e-06 27.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 AEO56860.1 - 0.00023 20.3 0.0 0.00072 18.6 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family BROMI PF14961.1 AEO56860.1 - 0.013 12.6 0.0 0.018 12.1 0.0 1.1 1 0 0 1 1 1 0 Broad-minded protein APH PF01636.18 AEO56860.1 - 0.073 12.7 0.2 0.17 11.5 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 AEO56860.1 - 0.15 11.3 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Ribosomal_L4 PF00573.17 AEO56861.1 - 1.6e-42 145.1 0.4 2e-42 144.7 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 AEO56861.1 - 1.9e-27 94.9 0.2 1.9e-27 94.9 0.2 1.8 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain DUF3812 PF12757.2 AEO56862.1 - 5e-35 120.2 15.9 5e-35 120.2 11.0 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF3812) GOLD_2 PF13897.1 AEO56862.1 - 0.018 15.2 0.6 0.018 15.2 0.4 2.0 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking VIT1 PF01988.14 AEO56862.1 - 0.82 9.1 2.5 3 7.2 1.8 2.0 1 0 0 1 1 1 0 VIT family Frag1 PF10277.4 AEO56863.1 - 5.1e-43 147.0 16.0 5.9e-43 146.8 11.1 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family 2TM PF13239.1 AEO56863.1 - 0.025 14.6 1.3 0.025 14.6 0.9 2.7 2 1 1 3 3 3 0 2TM domain DUF687 PF05095.7 AEO56863.1 - 0.034 12.5 1.3 0.045 12.1 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF687) Tetraspannin PF00335.15 AEO56863.1 - 0.18 11.0 10.6 0.02 14.1 2.9 2.1 2 0 0 2 2 2 0 Tetraspanin family TerC PF03741.11 AEO56863.1 - 0.39 10.1 11.5 1.1 8.7 1.9 2.5 1 1 2 3 3 3 0 Integral membrane protein TerC family Cation_efflux PF01545.16 AEO56863.1 - 7.4 5.5 19.1 5.1 6.0 9.8 2.0 1 1 1 2 2 2 0 Cation efflux family Pkinase PF00069.20 AEO56864.1 - 1.3e-65 221.1 0.0 1.8e-65 220.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO56864.1 - 6e-33 114.0 0.0 8.7e-33 113.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO56864.1 - 9.6e-05 21.4 0.0 0.00019 20.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Sec10 PF07393.6 AEO56865.1 - 2e-176 588.2 0.0 2.5e-176 587.9 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.2 AEO56865.1 - 4.7e-05 23.0 0.0 0.00012 21.7 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 AEO56865.1 - 6.4e-05 22.4 0.0 0.00012 21.6 0.0 1.5 1 0 0 1 1 1 1 F-box domain DUF1183 PF06682.7 AEO56865.1 - 3.2 7.2 5.7 0.26 10.8 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) zf-RING_2 PF13639.1 AEO56866.1 - 4.1e-09 36.1 11.6 7.9e-09 35.2 8.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 AEO56866.1 - 2.6e-08 33.3 9.0 5.2e-08 32.4 6.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AEO56866.1 - 3.5e-08 33.3 10.9 7.6e-08 32.2 7.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AEO56866.1 - 1e-06 28.2 9.4 2e-06 27.3 6.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO56866.1 - 1.3e-06 28.0 9.7 2.3e-06 27.2 6.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 AEO56866.1 - 6.8e-05 22.8 6.3 0.00017 21.6 4.4 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger Prok-RING_4 PF14447.1 AEO56866.1 - 7.1e-05 22.2 6.6 0.00016 21.1 4.5 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.1 AEO56866.1 - 0.0094 15.6 3.1 0.0094 15.6 2.2 2.5 2 0 0 2 2 2 1 RING-type zinc-finger Rad50_zn_hook PF04423.9 AEO56866.1 - 0.014 14.8 0.1 0.14 11.6 0.1 2.8 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-C3HC4_4 PF15227.1 AEO56866.1 - 0.017 15.0 9.4 0.034 14.0 6.5 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Helicase_C PF00271.26 AEO56866.1 - 0.018 14.8 0.0 0.05 13.4 0.0 1.8 1 0 0 1 1 1 0 Helicase conserved C-terminal domain SNF2_N PF00176.18 AEO56866.1 - 0.025 13.3 0.0 0.063 12.0 0.0 1.7 1 0 0 1 1 1 0 SNF2 family N-terminal domain zf-RING_6 PF14835.1 AEO56866.1 - 0.37 10.5 4.3 0.77 9.5 3.0 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein FYVE PF01363.16 AEO56866.1 - 2.2 8.2 8.5 7.9 6.4 5.9 2.0 1 1 0 1 1 1 0 FYVE zinc finger zf-P11 PF03854.9 AEO56866.1 - 2.8 7.4 10.0 0.58 9.6 4.4 1.7 2 0 0 2 2 2 0 P-11 zinc finger SlyX PF04102.7 AEO56866.1 - 8.2 6.8 8.6 1.9 8.9 0.1 4.1 3 1 0 3 3 3 0 SlyX SNF2_N PF00176.18 AEO56867.1 - 1.8e-49 168.2 0.0 2.3e-49 167.8 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain IGR PF09597.5 AEO56868.1 - 1.6e-24 85.5 0.1 2.4e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 IGR protein motif SAM_1 PF00536.25 AEO56868.1 - 0.004 17.3 0.0 0.008 16.3 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) TonB_2 PF13103.1 AEO56869.1 - 0.028 14.4 0.1 0.08 12.9 0.0 1.7 1 0 0 1 1 1 0 TonB C terminal bZIP_1 PF00170.16 AEO56869.1 - 0.07 13.0 0.1 0.07 13.0 0.1 1.9 2 0 0 2 2 2 0 bZIP transcription factor MDFI PF15316.1 AEO56869.1 - 5.1 7.0 6.6 6.1 6.7 4.5 1.3 1 0 0 1 1 1 0 MyoD family inhibitor NPR3 PF03666.8 AEO56869.1 - 6.1 5.2 12.2 7.9 4.8 8.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4551 PF15087.1 AEO56869.1 - 8.3 4.6 8.5 8.5 4.6 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SRP-alpha_N PF04086.8 AEO56869.1 - 8.8 5.6 12.5 9.7 5.4 8.6 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Macoilin PF09726.4 AEO56869.1 - 8.8 4.4 13.7 9.6 4.3 9.5 1.0 1 0 0 1 1 1 0 Transmembrane protein Glyco_hydro_63 PF03200.11 AEO56870.1 - 8.1e-244 811.1 0.0 8.4e-243 807.7 0.0 1.9 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 AEO56870.1 - 1.3e-05 24.1 0.1 2.3e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.9 AEO56870.1 - 0.015 14.0 0.0 0.023 13.4 0.0 1.3 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase RabGAP-TBC PF00566.13 AEO56871.1 - 6.7e-37 127.0 0.1 6.7e-37 127.0 0.0 2.0 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 AEO56871.1 - 5.7e-10 38.8 0.0 0.00013 21.3 0.0 4.3 5 0 0 5 5 5 3 Domain of unknown function (DUF3548) Mso1_Sec1_bdg PF14475.1 AEO56872.1 - 1.2e-19 69.4 0.1 1.8e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Mak16 PF04874.9 AEO56873.1 - 2.6e-24 85.2 34.7 1.6e-23 82.7 3.7 3.6 2 2 1 3 3 3 2 Mak16 protein C-terminal region Ribosomal_L28e PF01778.12 AEO56873.1 - 2.6e-06 27.8 0.0 2.6e-06 27.8 0.0 1.9 3 0 0 3 3 3 1 Ribosomal L28e protein family TFIIA PF03153.8 AEO56873.1 - 0.001 19.0 17.1 0.0015 18.5 11.8 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit CENP-T PF15511.1 AEO56873.1 - 0.088 12.0 18.5 0.12 11.6 12.8 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T BUD22 PF09073.5 AEO56873.1 - 5.2 6.0 42.0 8.6 5.3 29.1 1.5 1 1 0 1 1 1 0 BUD22 TrmE_N PF10396.4 AEO56874.1 - 1.6e-33 115.0 0.0 3.5e-33 113.9 0.0 1.6 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus GTPase_Cys_C PF12631.2 AEO56874.1 - 4.6e-20 71.8 0.9 1.6e-19 70.0 0.1 2.4 2 0 0 2 2 2 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE MMR_HSR1 PF01926.18 AEO56874.1 - 2.2e-17 63.0 0.0 3.9e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AEO56874.1 - 3.1e-05 23.3 0.0 9.9e-05 21.6 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 AEO56874.1 - 9.4e-05 22.2 0.0 0.00015 21.6 0.0 1.4 1 0 0 1 1 1 1 Dynamin family ABC_tran PF00005.22 AEO56874.1 - 0.0057 16.9 0.0 0.014 15.7 0.0 1.8 1 0 0 1 1 1 1 ABC transporter Miro PF08477.8 AEO56874.1 - 0.013 16.0 0.0 0.033 14.6 0.0 1.7 2 0 0 2 2 2 0 Miro-like protein Glyco_hydro_3_C PF01915.17 AEO56874.1 - 0.099 12.1 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain PP1_inhibitor PF05361.7 AEO56874.1 - 0.13 11.9 0.4 1.6 8.3 0.0 2.2 2 0 0 2 2 2 0 PKC-activated protein phosphatase-1 inhibitor DUF258 PF03193.11 AEO56874.1 - 0.17 11.0 0.0 0.38 9.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 XPG_I PF00867.13 AEO56876.1 - 0.00081 19.3 0.0 0.0016 18.4 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 AEO56876.1 - 0.021 15.0 0.0 0.11 12.7 0.0 2.2 2 1 0 2 2 2 0 XPG N-terminal domain Pox_Rap94 PF03294.9 AEO56876.1 - 0.08 10.8 0.0 0.11 10.4 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase-associated transcription specificity factor, Rap94 SecE PF00584.15 AEO56877.1 - 7.9e-12 44.5 0.0 8.9e-12 44.4 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Transthyretin PF00576.16 AEO56879.1 - 1.8e-25 89.0 0.1 4.1e-15 55.6 0.1 2.1 1 1 1 2 2 2 2 HIUase/Transthyretin family ArsA_ATPase PF02374.10 AEO56880.1 - 6e-113 376.8 0.0 6.9e-113 376.7 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 AEO56880.1 - 5e-16 58.6 0.1 2.8e-15 56.2 0.1 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 AEO56880.1 - 1.4e-08 34.8 0.0 1.4e-07 31.6 0.0 2.4 2 1 0 2 2 2 1 AAA domain Fer4_NifH PF00142.13 AEO56880.1 - 4.9e-06 25.9 0.0 9e-06 25.0 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 AEO56880.1 - 0.0001 21.8 0.1 0.0013 18.2 0.0 2.4 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 AEO56880.1 - 0.0049 16.3 0.0 0.0094 15.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AEO56880.1 - 0.0091 15.7 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 AEO56880.1 - 0.022 14.1 0.0 0.043 13.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein MipZ PF09140.6 AEO56880.1 - 0.024 13.7 0.0 0.051 12.6 0.0 1.5 1 0 0 1 1 1 0 ATPase MipZ YhjQ PF06564.7 AEO56880.1 - 0.025 13.9 0.0 0.058 12.7 0.0 1.5 1 0 0 1 1 1 0 YhjQ protein NB-ARC PF00931.17 AEO56880.1 - 0.093 11.5 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.1 AEO56880.1 - 0.11 12.7 0.1 0.28 11.4 0.0 1.7 2 0 0 2 2 1 0 AAA domain T2SE PF00437.15 AEO56880.1 - 0.13 11.1 0.1 0.33 9.7 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein DWNN PF08783.6 AEO56882.1 - 7.2e-28 96.3 0.0 1.4e-27 95.3 0.0 1.5 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.1 AEO56882.1 - 0.0011 18.4 5.3 0.0042 16.5 3.7 2.0 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 AEO56882.1 - 0.01 15.7 1.5 0.01 15.7 1.0 1.9 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.1 AEO56882.1 - 0.024 14.3 0.5 0.059 13.1 0.3 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-RING_6 PF14835.1 AEO56882.1 - 0.031 14.0 1.8 0.058 13.1 1.3 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Nse PF11789.3 AEO56882.1 - 0.097 12.2 7.0 0.21 11.1 4.9 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 AEO56882.1 - 0.14 11.7 6.7 0.35 10.4 4.6 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 AEO56882.1 - 0.49 10.3 10.8 1.4 8.8 7.5 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 AEO56882.1 - 0.52 10.0 12.1 0.035 13.8 4.5 2.0 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.20 AEO56882.1 - 1.5 8.5 10.5 3 7.5 7.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AEO56882.1 - 3.7 7.6 15.6 0.32 11.0 6.5 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PRELI PF04707.9 AEO56883.1 - 3.1e-21 75.5 0.0 4.6e-18 65.2 0.0 2.1 2 0 0 2 2 2 2 PRELI-like family Ribosomal_60s PF00428.14 AEO56883.1 - 0.088 13.2 3.3 0.19 12.1 0.6 2.1 1 1 1 2 2 2 0 60s Acidic ribosomal protein Peptidase_S10 PF00450.17 AEO56884.1 - 7.9e-86 288.8 0.0 1.1e-85 288.3 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase DUF2614 PF11023.3 AEO56884.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2614) RF-1 PF00472.15 AEO56885.1 - 7.7e-34 115.9 2.3 1.9e-33 114.6 1.6 1.6 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 AEO56885.1 - 7.4e-28 96.5 0.0 4.1e-27 94.1 0.0 2.2 2 0 0 2 2 2 1 PCRF domain MIR PF02815.14 AEO56885.1 - 0.025 14.1 0.0 0.08 12.4 0.0 1.7 1 1 0 1 1 1 0 MIR domain HEAT_EZ PF13513.1 AEO56885.1 - 4.2 7.9 6.7 22 5.7 0.1 2.9 3 0 0 3 3 3 0 HEAT-like repeat tRNA-synt_1b PF00579.20 AEO56886.1 - 1.4e-20 73.6 0.1 3.2e-20 72.4 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (W and Y) 2CSK_N PF08521.5 AEO56886.1 - 0.17 11.4 0.1 0.28 10.6 0.1 1.2 1 0 0 1 1 1 0 Two-component sensor kinase N-terminal G_glu_transpept PF01019.16 AEO56887.1 - 1e-144 482.8 0.0 1.2e-144 482.6 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Glutaredoxin PF00462.19 AEO56888.1 - 2.5e-16 59.4 0.0 5.7e-16 58.2 0.0 1.6 2 0 0 2 2 2 1 Glutaredoxin Synthase_beta PF11421.3 AEO56888.1 - 0.24 12.0 2.6 1.6 9.4 0.0 2.3 2 0 0 2 2 2 0 ATP synthase F1 beta subunit adh_short PF00106.20 AEO56889.1 - 1.2e-16 61.0 0.6 4.5e-16 59.2 0.1 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 AEO56889.1 - 2.3e-11 43.6 0.1 3.8e-11 42.9 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 AEO56889.1 - 0.018 14.4 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 AEO56889.1 - 0.026 14.6 0.0 0.061 13.4 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 AEO56889.1 - 0.078 11.8 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein CoA_transf_3 PF02515.12 AEO56890.1 - 5.9e-55 185.4 1.1 7.8e-55 185.0 0.7 1.2 1 0 0 1 1 1 1 CoA-transferase family III Dynamin_M PF01031.15 AEO56891.1 - 3.4e-107 357.6 0.1 3.4e-107 357.6 0.1 2.0 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 AEO56891.1 - 9.3e-57 191.4 0.0 2e-56 190.4 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 AEO56891.1 - 3.1e-28 97.4 6.6 3.1e-28 97.4 4.6 2.3 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 AEO56891.1 - 0.00033 20.5 0.2 0.0057 16.5 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 AEO56891.1 - 0.0073 16.7 0.0 0.03 14.8 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein WD40 PF00400.27 AEO56892.1 - 5.4e-35 118.0 12.1 1.2e-06 28.1 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 AEO56892.1 - 0.00015 21.5 0.0 0.0051 16.5 0.0 2.6 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 AEO56892.1 - 0.00055 18.2 1.9 0.0091 14.1 0.9 2.6 1 1 1 2 2 2 1 Nucleoporin Nup120/160 CLTH PF10607.4 AEO56892.1 - 0.00059 19.5 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain DUF4221 PF13970.1 AEO56892.1 - 0.038 13.3 0.0 0.059 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4221) PD40 PF07676.7 AEO56892.1 - 0.12 12.0 0.1 3.6 7.3 0.0 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Peptidase_S9_N PF02897.10 AEO56892.1 - 0.17 10.4 0.1 0.91 8.0 0.1 2.1 1 1 0 1 1 1 0 Prolyl oligopeptidase, N-terminal beta-propeller domain BUD22 PF09073.5 AEO56893.1 - 0.00067 18.8 4.1 0.0013 17.9 2.8 1.4 1 0 0 1 1 1 1 BUD22 Cwf_Cwc_15 PF04889.7 AEO56893.1 - 6.3 6.4 11.6 12 5.5 8.1 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CAS_CSE1 PF03378.10 AEO56894.1 - 2.2e-174 579.8 0.0 8.5e-174 577.9 0.0 2.0 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 AEO56894.1 - 7.4e-147 488.7 2.2 1.2e-146 488.0 1.5 1.3 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.14 AEO56894.1 - 3.1e-11 43.0 0.1 1.1e-10 41.2 0.0 2.0 2 0 0 2 2 2 1 Importin-beta N-terminal domain V-ATPase_H_N PF03224.9 AEO56894.1 - 0.016 14.3 0.4 0.14 11.2 0.1 2.5 3 0 0 3 3 3 0 V-ATPase subunit H HEAT_2 PF13646.1 AEO56894.1 - 0.016 15.4 3.1 0.066 13.5 0.0 3.3 3 1 1 4 4 4 0 HEAT repeats Xpo1 PF08389.7 AEO56894.1 - 0.068 13.0 1.7 2.4 8.0 0.0 3.7 3 1 0 3 3 3 0 Exportin 1-like protein Ric8 PF10165.4 AEO56894.1 - 0.35 9.6 0.9 4 6.1 0.1 2.3 2 0 0 2 2 2 0 Guanine nucleotide exchange factor synembryn DUF3384 PF11864.3 AEO56895.1 - 2.5e-109 365.8 0.0 5.3e-109 364.7 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.10 AEO56895.1 - 2e-54 183.8 0.0 3.5e-54 183.0 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.11 AEO56895.1 - 1e-32 113.6 0.3 2.5e-29 102.4 0.0 2.3 2 0 0 2 2 2 2 Tuberin Acetyltransf_1 PF00583.19 AEO56896.1 - 4.2e-09 36.3 0.0 6.3e-07 29.3 0.0 2.6 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 AEO56896.1 - 2.7e-05 24.2 0.1 0.00017 21.6 0.0 2.3 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 AEO56896.1 - 0.0045 17.1 0.0 0.01 15.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 AEO56896.1 - 0.013 15.2 0.0 0.06 13.1 0.0 2.2 2 0 0 2 2 2 0 FR47-like protein DUF3749 PF12568.3 AEO56896.1 - 0.018 14.6 0.1 0.069 12.7 0.3 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 AEO56896.1 - 0.031 14.1 0.0 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain CENP-I PF07778.6 AEO56897.1 - 4.9e-99 331.8 0.1 9.6e-54 182.4 0.0 2.1 1 1 1 2 2 2 2 Mis6 ABC_tran PF00005.22 AEO56898.1 - 3.6e-15 56.4 0.0 1.8e-14 54.1 0.0 1.9 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 AEO56898.1 - 2.4e-10 40.8 0.0 0.00042 20.3 0.0 2.1 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 AEO56898.1 - 0.00025 20.2 0.0 0.31 10.0 0.0 2.0 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 AEO56898.1 - 0.0006 19.2 0.1 0.0012 18.3 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3584 PF12128.3 AEO56898.1 - 0.00089 16.7 0.4 0.0012 16.3 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_16 PF13191.1 AEO56898.1 - 0.0015 18.5 0.1 0.0033 17.4 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.14 AEO56898.1 - 0.0057 15.9 0.0 2.7 7.1 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain PduV-EutP PF10662.4 AEO56898.1 - 0.011 15.2 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 AEO56898.1 - 0.012 15.1 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_23 PF13476.1 AEO56898.1 - 0.012 15.9 0.0 0.017 15.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 AEO56898.1 - 0.015 15.2 0.7 0.028 14.4 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 AEO56898.1 - 0.016 15.3 0.2 0.089 12.9 0.2 2.0 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 AEO56898.1 - 0.017 14.6 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_17 PF13207.1 AEO56898.1 - 0.018 15.8 0.7 0.041 14.6 0.5 1.8 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 AEO56898.1 - 0.022 14.1 1.2 0.077 12.3 0.8 2.0 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 AEO56898.1 - 0.024 14.8 0.0 0.095 12.8 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 AEO56898.1 - 0.032 13.4 0.0 0.049 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Arf PF00025.16 AEO56898.1 - 0.037 13.2 0.1 0.073 12.3 0.0 1.5 1 1 0 1 1 1 0 ADP-ribosylation factor family AAA_33 PF13671.1 AEO56898.1 - 0.043 13.6 0.0 0.069 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 AEO56898.1 - 0.078 12.4 0.1 0.11 11.9 0.1 1.3 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_14 PF13173.1 AEO56898.1 - 0.14 12.0 0.0 0.38 10.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.1 AEO56898.1 - 0.14 10.5 0.0 0.19 10.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 AEO56898.1 - 0.14 11.7 0.1 0.24 11.0 0.1 1.3 1 0 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.7 AEO56898.1 - 0.15 11.1 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin cobW PF02492.14 AEO56898.1 - 0.21 10.9 0.3 0.33 10.3 0.2 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Transglut_core PF01841.14 AEO56899.1 - 4e-11 43.1 0.3 2.3e-10 40.6 0.1 2.2 2 0 0 2 2 2 1 Transglutaminase-like superfamily SH3_2 PF07653.12 AEO56899.1 - 5.2e-09 35.4 0.1 1.2e-08 34.2 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 AEO56899.1 - 1e-05 24.7 2.6 1.3e-05 24.4 0.0 2.4 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 AEO56899.1 - 0.00014 21.4 0.1 0.00033 20.1 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain Pkinase PF00069.20 AEO56900.1 - 9.1e-69 231.4 0.0 1.3e-68 231.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO56900.1 - 3e-48 164.1 0.0 5.7e-48 163.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO56900.1 - 1.9e-05 23.7 0.0 0.0002 20.3 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Ndc1_Nup PF09531.5 AEO56900.1 - 2.5 6.4 7.6 4.5 5.5 5.2 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RAI1 PF08652.6 AEO56901.1 - 3.1e-29 100.5 0.0 7e-29 99.4 0.0 1.6 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease ResIII PF04851.10 AEO56901.1 - 0.059 13.2 0.0 0.17 11.6 0.0 1.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Sec8_exocyst PF04048.9 AEO56902.1 - 4.2e-49 165.8 0.2 1e-48 164.6 0.1 1.7 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 AEO56902.1 - 4.3e-09 35.7 1.7 7.6e-09 34.8 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) DUF3737 PF12541.3 AEO56902.1 - 0.012 14.6 0.0 0.019 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3737) SMI1_KNR4 PF09346.5 AEO56903.1 - 7.6e-36 122.9 0.0 1.2e-35 122.3 0.0 1.3 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) UPF0220 PF05255.6 AEO56904.1 - 4.8e-62 208.0 1.8 5.4e-62 207.9 1.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Pkinase PF00069.20 AEO56905.1 - 1.7e-63 214.1 0.0 2.3e-63 213.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO56905.1 - 1.8e-25 89.5 0.0 2.4e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO56905.1 - 8.5e-08 31.4 0.0 3e-07 29.7 0.0 1.7 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 AEO56905.1 - 0.00025 20.8 0.1 0.0054 16.4 0.0 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 AEO56905.1 - 0.072 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase MIF4G_like PF09088.6 AEO56906.1 - 1.3e-86 288.9 0.1 2.1e-86 288.2 0.0 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 AEO56906.1 - 9.5e-55 185.5 0.0 1.4e-54 185.0 0.0 1.2 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.14 AEO56906.1 - 0.007 15.8 0.0 0.026 13.9 0.0 1.9 2 0 0 2 2 2 1 MIF4G domain RRM_1 PF00076.17 AEO56907.1 - 3.8e-34 116.1 0.0 4.7e-16 58.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO56907.1 - 1.7e-17 63.1 0.0 2.1e-08 33.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO56907.1 - 1.7e-16 59.8 0.0 2.7e-07 30.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 AEO56907.1 - 0.00086 18.7 0.1 0.82 9.2 0.0 2.4 2 0 0 2 2 2 2 Ribonuclease B OB domain Limkain-b1 PF11608.3 AEO56907.1 - 0.026 14.2 0.0 2.3 8.0 0.0 2.2 2 0 0 2 2 2 0 Limkain b1 Tom7 PF08038.7 AEO56908.1 - 7.4e-20 70.1 0.1 8.4e-20 69.9 0.1 1.0 1 0 0 1 1 1 1 TOM7 family Mito_carr PF00153.22 AEO56909.1 - 2.8e-59 196.8 1.1 3.7e-19 68.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PPDFL PF15060.1 AEO56909.1 - 0.089 12.7 0.8 6 6.9 0.0 2.4 2 0 0 2 2 2 0 Differentiation and proliferation regulator zf-C2H2 PF00096.21 AEO56910.1 - 1.2e-14 53.6 24.2 4.2e-06 26.7 1.0 4.7 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 AEO56910.1 - 8.5e-14 51.0 9.6 7.8e-08 32.2 0.5 5.1 5 1 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 AEO56910.1 - 1.6e-07 31.1 17.3 0.0001 22.4 1.2 5.3 6 0 0 6 6 6 3 C2H2-type zinc finger zf-RING_3 PF14369.1 AEO56910.1 - 0.67 9.9 6.6 2.9 7.9 0.1 3.1 3 0 0 3 3 3 0 zinc-finger FYDLN_acid PF09538.5 AEO56910.1 - 1.4 9.5 17.6 13 6.4 0.1 4.4 3 1 1 4 4 4 0 Protein of unknown function (FYDLN_acid) Suf PF05843.9 AEO56910.1 - 4.7 6.8 14.8 0.25 11.0 4.8 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) C1_4 PF07975.7 AEO56910.1 - 5.2 7.1 12.3 12 5.9 2.6 3.3 1 1 2 3 3 3 0 TFIIH C1-like domain Urm1 PF09138.6 AEO56911.1 - 5e-34 116.3 0.0 5.7e-34 116.1 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 AEO56911.1 - 0.0023 18.2 0.0 0.0029 18.0 0.0 1.2 1 0 0 1 1 1 1 ThiS family Pyridox_oxidase PF01243.15 AEO56911.1 - 0.13 12.2 0.1 12 6.0 0.0 2.5 2 1 1 3 3 3 0 Pyridoxamine 5'-phosphate oxidase WD40 PF00400.27 AEO56912.1 - 3.4e-63 207.4 13.7 4.3e-07 29.5 0.0 12.6 13 0 0 13 13 13 10 WD domain, G-beta repeat DUF3317 PF11779.3 AEO56913.1 - 1.1e-18 66.4 7.3 1.2e-18 66.2 5.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) DUF1624 PF07786.7 AEO56913.1 - 0.032 13.5 1.1 0.036 13.3 0.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1624) Ion_trans_N PF08412.5 AEO56913.1 - 0.32 10.3 2.1 0.4 10.0 1.5 1.3 1 0 0 1 1 1 0 Ion transport protein N-terminal Actin PF00022.14 AEO56914.1 - 4.1e-159 529.2 0.0 4.7e-159 529.0 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 AEO56914.1 - 0.039 14.3 0.0 0.12 12.8 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Fes1 PF08609.5 AEO56915.1 - 1.3e-35 121.7 0.5 3.3e-35 120.4 0.3 1.7 1 0 0 1 1 1 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.1 AEO56915.1 - 3.5e-06 27.2 1.9 6.7e-06 26.3 0.4 2.2 1 1 1 2 2 2 2 HEAT repeats Arm PF00514.18 AEO56915.1 - 2e-05 24.2 0.0 0.44 10.4 0.0 3.1 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT PF02985.17 AEO56915.1 - 0.0011 18.9 0.4 0.082 13.0 0.0 2.8 2 0 0 2 2 2 1 HEAT repeat HEAT_EZ PF13513.1 AEO56915.1 - 0.0022 18.3 2.5 0.0069 16.8 0.9 2.5 2 1 1 3 3 3 2 HEAT-like repeat Aconitase_B_N PF11791.3 AEO56915.1 - 0.0067 16.2 0.2 0.18 11.6 0.0 2.4 2 1 0 2 2 2 1 Aconitate B N-terminal domain Ribosomal_L5_C PF00673.16 AEO56916.1 - 6.3e-24 83.5 0.0 9.8e-24 82.9 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 AEO56916.1 - 7.1e-06 25.7 0.0 1.2e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 MMR_HSR1 PF01926.18 AEO56917.1 - 1.5e-17 63.6 0.2 2.6e-15 56.4 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AEO56917.1 - 2.4e-07 30.1 0.2 1e-05 24.8 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 AEO56917.1 - 0.00014 21.7 0.1 0.016 15.0 0.0 2.6 2 0 0 2 2 2 1 Dynamin family DUF258 PF03193.11 AEO56917.1 - 0.00039 19.6 0.0 0.00071 18.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 AEO56917.1 - 0.017 14.2 0.0 0.029 13.4 0.0 1.4 1 0 0 1 1 1 0 AIG1 family Miro PF08477.8 AEO56917.1 - 0.029 14.8 0.0 0.084 13.3 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein DUF3415 PF11895.3 AEO56917.1 - 0.057 13.2 0.0 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3415) GTP_EFTU PF00009.22 AEO56917.1 - 0.079 12.3 0.0 2.2 7.6 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF4632 PF15451.1 AEO56917.1 - 0.56 10.1 3.8 2.8 7.9 2.6 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) LTV PF04180.9 AEO56918.1 - 2.9e-98 330.1 11.2 3.6e-98 329.8 7.8 1.0 1 0 0 1 1 1 1 Low temperature viability protein Aminotran_1_2 PF00155.16 AEO56919.1 - 4.2e-09 35.8 0.0 6.9e-08 31.8 0.0 2.2 2 0 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 AEO56919.1 - 0.11 11.5 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase FMO-like PF00743.14 AEO56920.1 - 4.3e-43 147.3 0.0 4.1e-26 91.2 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 AEO56920.1 - 2.1e-16 60.5 0.1 2.5e-15 57.0 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 AEO56920.1 - 1.8e-15 57.0 0.0 1.1e-14 54.4 0.0 2.4 4 0 0 4 4 4 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 AEO56920.1 - 2.7e-10 39.6 1.6 2.1e-07 30.1 0.0 3.0 2 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 AEO56920.1 - 3.1e-08 33.0 0.0 4.1e-06 26.0 0.0 2.3 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 AEO56920.1 - 4.9e-08 33.0 0.0 8e-07 29.1 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AEO56920.1 - 5.6e-07 29.4 0.0 1.8e-06 27.9 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 AEO56920.1 - 0.0016 17.4 0.0 0.087 11.7 0.0 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 AEO56920.1 - 0.0027 16.2 0.3 0.054 11.9 0.1 2.5 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_3 PF01494.14 AEO56920.1 - 0.092 11.7 0.0 0.21 10.5 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 AEO56920.1 - 0.16 12.3 0.3 6.3 7.2 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Malic_M PF03949.10 AEO56922.1 - 5.4e-88 294.8 0.0 7e-88 294.4 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 AEO56922.1 - 6.8e-71 237.6 0.0 1.1e-70 236.8 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Golgin_A5 PF09787.4 AEO56923.1 - 0.78 8.1 6.2 0.94 7.9 4.3 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 RAP1 PF07218.6 AEO56923.1 - 1.9 6.4 7.8 2.2 6.2 5.4 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) LRR_8 PF13855.1 AEO56924.1 - 9.4e-05 22.0 1.1 3.9 7.2 0.0 5.2 5 2 1 6 6 6 2 Leucine rich repeat GATA PF00320.22 AEO56924.1 - 0.00068 18.9 3.3 0.0018 17.5 0.6 2.3 2 0 0 2 2 2 1 GATA zinc finger LRR_6 PF13516.1 AEO56924.1 - 0.011 15.6 3.7 12 6.3 0.0 6.0 8 0 0 8 8 8 0 Leucine Rich repeat SRP-alpha_N PF04086.8 AEO56924.1 - 0.066 12.5 7.6 0.1 11.9 5.3 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal FYVE PF01363.16 AEO56924.1 - 0.07 13.0 0.1 0.23 11.4 0.1 1.8 1 0 0 1 1 1 0 FYVE zinc finger DRP PF06044.7 AEO56924.1 - 0.088 11.7 0.1 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 Dam-replacing family SNF2_N PF00176.18 AEO56925.1 - 1.9e-63 214.0 0.0 3.2e-63 213.3 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AEO56925.1 - 2.7e-13 49.5 0.0 8.5e-13 47.9 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 AEO56925.1 - 5.4e-08 32.5 0.1 2.6e-06 27.0 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 AEO56925.1 - 1.9e-07 31.1 0.0 6.8e-07 29.3 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.20 AEO56925.1 - 1.5e-06 27.7 13.7 1.5e-06 27.7 9.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AEO56925.1 - 0.00044 20.0 12.7 0.00044 20.0 8.8 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 AEO56925.1 - 0.001 19.0 12.7 0.001 19.0 8.8 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 AEO56925.1 - 6.6 6.3 11.3 1.1 8.8 4.8 2.0 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit DUF1793 PF08760.6 AEO56926.1 - 1.1e-79 266.2 0.1 5.4e-79 263.9 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) Bac_rhamnosid PF05592.6 AEO56926.1 - 0.015 13.5 0.2 0.17 10.0 0.3 2.1 2 0 0 2 2 2 0 Bacterial alpha-L-rhamnosidase RRM_1 PF00076.17 AEO56927.1 - 3e-19 68.4 0.0 4.3e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO56927.1 - 2.6e-17 62.5 0.0 3.7e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO56927.1 - 2.2e-12 46.6 0.0 3.1e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ABC_tran PF00005.22 AEO56928.1 - 2.5e-49 167.0 0.0 1.2e-27 96.9 0.0 3.0 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.18 AEO56928.1 - 6.3e-48 163.5 35.3 2.4e-28 99.3 11.0 3.2 3 0 0 3 3 3 3 ABC transporter transmembrane region AAA_16 PF13191.1 AEO56928.1 - 4.6e-06 26.7 0.1 0.027 14.4 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 AEO56928.1 - 6.1e-06 26.4 0.1 1.1 9.0 0.0 3.8 3 1 0 3 3 3 2 AAA domain Miro PF08477.8 AEO56928.1 - 1.2e-05 25.8 0.5 0.064 13.7 0.0 3.0 3 0 0 3 3 2 2 Miro-like protein MMR_HSR1 PF01926.18 AEO56928.1 - 3.2e-05 23.8 0.3 0.19 11.7 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase Zeta_toxin PF06414.7 AEO56928.1 - 6e-05 22.2 0.1 0.03 13.4 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin SMC_N PF02463.14 AEO56928.1 - 0.00013 21.2 0.5 4.2 6.5 0.0 3.3 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 AEO56928.1 - 0.00014 21.0 1.2 0.058 12.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 AEO56928.1 - 0.00016 21.0 1.0 0.37 10.3 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.1 AEO56928.1 - 0.00035 20.1 0.7 0.34 10.4 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 AEO56928.1 - 0.0011 19.3 1.3 0.54 10.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 AEO56928.1 - 0.0013 18.2 0.0 0.33 10.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 AEO56928.1 - 0.0026 18.5 4.1 0.5 11.1 0.5 3.0 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 AEO56928.1 - 0.003 17.0 1.1 2.3 7.5 0.1 2.7 3 0 0 3 3 3 2 AAA-like domain ArgK PF03308.11 AEO56928.1 - 0.0051 15.6 1.8 0.58 8.8 0.2 2.4 2 0 0 2 2 2 1 ArgK protein AAA_22 PF13401.1 AEO56928.1 - 0.0058 16.7 0.5 2.2 8.4 0.0 3.2 2 1 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.4 AEO56928.1 - 0.0083 14.7 1.0 0.46 9.0 0.0 2.2 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.12 AEO56928.1 - 0.011 15.5 3.4 0.11 12.2 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 MobB PF03205.9 AEO56928.1 - 0.012 15.2 1.1 1.6 8.4 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 AEO56928.1 - 0.016 15.0 2.6 0.21 11.3 0.1 2.6 2 0 0 2 2 2 0 Dynamin family FtsK_SpoIIIE PF01580.13 AEO56928.1 - 0.027 13.9 0.0 3.7 6.9 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family ATP-synt_ab PF00006.20 AEO56928.1 - 0.03 13.8 0.4 8.1 5.8 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_28 PF13521.1 AEO56928.1 - 0.04 13.8 1.7 0.095 12.6 0.0 2.5 3 0 0 3 3 2 0 AAA domain AAA_18 PF13238.1 AEO56928.1 - 0.047 14.0 1.2 2.4 8.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 AEO56928.1 - 0.05 13.2 0.5 0.42 10.2 0.0 2.3 2 0 0 2 2 2 0 NACHT domain SRP54 PF00448.17 AEO56928.1 - 0.062 12.7 0.2 0.69 9.3 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain T2SE PF00437.15 AEO56928.1 - 0.086 11.7 0.1 1.7 7.4 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein ATP_bind_1 PF03029.12 AEO56928.1 - 0.15 11.5 1.4 7.3 6.0 0.1 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein cobW PF02492.14 AEO56928.1 - 0.26 10.7 2.4 0.68 9.3 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.1 AEO56928.1 - 0.82 8.6 0.0 15 4.5 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain Nop14 PF04147.7 AEO56929.1 - 6.2 4.6 5.2 7.9 4.2 3.6 1.0 1 0 0 1 1 1 0 Nop14-like family Fcf1 PF04900.7 AEO56930.1 - 2.1e-39 133.7 1.7 3.5e-39 132.9 0.2 1.9 2 0 0 2 2 2 1 Fcf1 Telomere_Sde2 PF13019.1 AEO56930.1 - 0.049 13.3 1.5 0.076 12.7 1.0 1.3 1 0 0 1 1 1 0 Telomere stability and silencing NmrA PF05368.8 AEO56931.1 - 9.6e-80 267.1 0.0 1.2e-79 266.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 AEO56931.1 - 1.6e-05 24.9 0.1 0.00031 20.7 0.1 2.2 1 1 0 1 1 1 1 NADH(P)-binding DUF2498 PF10692.4 AEO56931.1 - 0.078 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2498) ERG2_Sigma1R PF04622.7 AEO56932.1 - 1.7e-93 311.8 0.1 2e-93 311.6 0.0 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein EXOSC1 PF10447.4 AEO56933.1 - 2e-28 98.1 0.5 3.3e-28 97.4 0.4 1.3 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 AEO56933.1 - 2.1e-14 52.4 0.1 4.7e-14 51.3 0.1 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region S1 PF00575.18 AEO56933.1 - 0.019 15.0 0.2 0.15 12.1 0.1 2.1 1 1 0 1 1 1 0 S1 RNA binding domain TOM_sub5 PF15178.1 AEO56933.1 - 0.15 11.8 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit TOM5 homolog Sec2p PF06428.6 AEO56934.1 - 1e-10 41.3 6.4 1e-10 41.3 4.5 3.1 3 1 0 3 3 3 1 GDP/GTP exchange factor Sec2p PAT1 PF09770.4 AEO56934.1 - 0.0017 16.7 36.2 0.0019 16.5 25.1 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 DUF1936 PF09151.5 AEO56934.1 - 0.15 11.6 0.3 0.26 10.8 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1936) Ndc1_Nup PF09531.5 AEO56934.1 - 0.26 9.6 14.8 0.31 9.4 10.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF605 PF04652.11 AEO56934.1 - 0.27 10.5 30.1 0.33 10.2 20.9 1.2 1 0 0 1 1 1 0 Vta1 like V_ATPase_I PF01496.14 AEO56934.1 - 2 6.2 7.0 1.9 6.2 0.2 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family GAS PF13851.1 AEO56934.1 - 3.3 6.8 15.9 0.66 9.1 0.1 2.7 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding AAA_13 PF13166.1 AEO56934.1 - 3.8 5.8 5.5 5.3 5.3 0.2 2.2 2 0 0 2 2 2 0 AAA domain DUF972 PF06156.8 AEO56934.1 - 5.5 7.3 16.9 0.19 12.0 0.8 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF972) TruB_N PF01509.13 AEO56935.1 - 1.8e-45 154.7 1.0 4.7e-45 153.3 0.0 2.0 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) MCR_D PF02505.9 AEO56936.1 - 0.21 11.1 0.0 0.37 10.3 0.0 1.3 1 0 0 1 1 1 0 Methyl-coenzyme M reductase operon protein D Methyltransf_23 PF13489.1 AEO56937.1 - 9e-15 54.7 0.0 1.5e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO56937.1 - 7e-14 52.0 0.1 1.1e-06 28.9 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 AEO56937.1 - 1.1e-10 41.2 0.0 0.0004 19.9 0.1 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 AEO56937.1 - 2.3e-10 41.0 0.2 6e-10 39.7 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO56937.1 - 2.9e-10 40.5 0.0 7.9e-05 23.0 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain CMAS PF02353.15 AEO56937.1 - 5.5e-09 35.5 0.0 5.6e-08 32.1 0.0 2.0 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 AEO56937.1 - 1e-06 28.7 1.5 9.4e-06 25.6 1.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO56937.1 - 3.8e-06 27.2 0.0 5.1e-05 23.5 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.7 AEO56937.1 - 0.0017 17.6 0.0 0.54 9.5 0.0 2.2 2 0 0 2 2 2 2 AdoMet dependent proline di-methyltransferase Ribosomal_60s PF00428.14 AEO56937.1 - 0.0057 17.0 4.1 0.021 15.2 1.4 2.4 2 0 0 2 2 2 1 60s Acidic ribosomal protein Ubie_methyltran PF01209.13 AEO56937.1 - 0.014 14.5 0.0 0.34 9.9 0.0 2.2 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family MTS PF05175.9 AEO56937.1 - 0.018 14.3 0.1 0.9 8.8 0.1 2.2 2 0 0 2 2 2 0 Methyltransferase small domain Kinesin PF00225.18 AEO56938.1 - 2e-110 368.6 0.4 7.2e-110 366.8 0.0 2.0 2 0 0 2 2 2 1 Kinesin motor domain DUF3694 PF12473.3 AEO56938.1 - 1.2e-45 154.6 0.0 3.2e-45 153.2 0.0 1.8 1 0 0 1 1 1 1 Kinesin protein FHA PF00498.21 AEO56938.1 - 5.9e-07 29.5 0.0 4e-06 26.8 0.0 2.4 2 0 0 2 2 2 1 FHA domain KIF1B PF12423.3 AEO56938.1 - 2.5e-06 27.3 7.0 5e-06 26.4 0.5 2.9 2 0 0 2 2 2 1 Kinesin protein 1B PH PF00169.24 AEO56938.1 - 0.0048 17.0 0.0 0.04 14.1 0.0 2.4 1 1 0 1 1 1 1 PH domain Peptidase_M1 PF01433.15 AEO56939.1 - 1.5e-72 244.8 0.0 1.9e-72 244.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 AEO56939.1 - 9.9e-47 158.1 0.0 1.6e-46 157.4 0.0 1.4 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 AEO56939.1 - 9.4e-16 58.0 0.1 1.7e-15 57.2 0.1 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 AEO56939.1 - 0.075 13.0 1.5 0.42 10.6 1.0 2.2 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Svf1 PF08622.5 AEO56939.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Svf1-like YscO PF07321.7 AEO56940.1 - 0.011 15.6 7.9 0.014 15.2 5.5 1.1 1 0 0 1 1 1 0 Type III secretion protein YscO APG6 PF04111.7 AEO56940.1 - 0.014 14.5 1.9 0.016 14.2 1.3 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 OmpH PF03938.9 AEO56940.1 - 0.023 14.6 0.6 0.027 14.4 0.4 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1599 PF07659.6 AEO56940.1 - 0.035 14.1 2.7 2.9 8.0 0.1 2.2 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1599) Uds1 PF15456.1 AEO56940.1 - 0.049 13.6 4.1 0.078 12.9 2.9 1.3 1 0 0 1 1 1 0 Up-regulated During Septation DUF1664 PF07889.7 AEO56940.1 - 0.079 12.7 0.3 0.11 12.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Fzo_mitofusin PF04799.8 AEO56940.1 - 0.11 11.8 1.3 0.15 11.4 0.9 1.1 1 0 0 1 1 1 0 fzo-like conserved region V_ATPase_I PF01496.14 AEO56940.1 - 0.2 9.5 0.2 0.22 9.3 0.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF724 PF05266.9 AEO56940.1 - 0.22 11.0 3.0 0.28 10.7 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) FlgN PF05130.7 AEO56940.1 - 0.26 11.5 8.0 0.51 10.5 5.6 1.4 1 1 0 1 1 1 0 FlgN protein CALCOCO1 PF07888.6 AEO56940.1 - 0.3 9.3 8.1 0.35 9.1 5.6 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2852 PF11014.3 AEO56940.1 - 2.4 8.1 7.0 5.8 6.8 4.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2852) Uds1 PF15456.1 AEO56941.1 - 6.3e-29 100.4 8.8 2.2e-22 79.3 4.8 2.6 2 0 0 2 2 2 2 Up-regulated During Septation AT_hook PF02178.14 AEO56942.1 - 0.41 10.4 6.4 1.4 8.8 4.4 2.0 1 0 0 1 1 1 0 AT hook motif CN_hydrolase PF00795.17 AEO56943.1 - 6.2e-31 107.1 0.0 2.6e-30 105.1 0.0 1.9 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase DUF3682 PF12446.3 AEO56943.1 - 0.054 13.7 0.5 0.11 12.7 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Spermine_synth PF01564.12 AEO56944.1 - 9.2e-100 332.6 0.0 1.3e-99 332.1 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_18 PF12847.2 AEO56944.1 - 0.00011 22.6 0.0 0.0002 21.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO56944.1 - 0.00015 21.7 0.0 0.0003 20.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO56944.1 - 0.0004 19.9 0.0 0.0006 19.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.11 AEO56944.1 - 0.0016 17.4 0.0 0.0025 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF43 Methyltransf_2 PF00891.13 AEO56944.1 - 0.0071 15.5 0.2 0.074 12.2 0.1 2.2 1 1 1 2 2 2 1 O-methyltransferase Methyltransf_12 PF08242.7 AEO56944.1 - 0.008 16.6 0.2 0.026 14.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO56944.1 - 0.034 13.8 0.0 0.1 12.3 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain G-alpha PF00503.15 AEO56945.1 - 6.6e-119 397.0 0.1 8e-119 396.7 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 AEO56945.1 - 1.4e-13 50.4 0.7 2.1e-08 33.5 0.1 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 AEO56945.1 - 0.0004 19.6 0.9 0.051 12.7 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.13 AEO56945.1 - 0.025 14.0 0.0 0.048 13.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_25 PF13481.1 AEO56945.1 - 0.036 13.4 0.0 0.064 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 AEO56945.1 - 0.055 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 AEO56945.1 - 0.11 11.9 0.0 2.1 7.7 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Glyco_hydro_3_C PF01915.17 AEO56946.1 - 3.8e-42 144.3 0.0 8.2e-41 139.9 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 AEO56946.1 - 4.4e-21 74.5 0.1 7.3e-21 73.8 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_10 PF00331.15 AEO56947.1 - 7e-14 51.5 0.0 7.9e-14 51.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 GATase_2 PF00310.16 AEO56948.1 - 6.3e-21 74.4 0.1 4.1e-16 58.6 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 AEO56948.1 - 4.2e-16 59.1 0.0 7.8e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 AEO56948.1 - 1.1e-15 57.4 0.0 2e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 AEO56948.1 - 1.7e-11 43.8 0.1 3.1e-11 43.0 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 AEO56948.1 - 1.8e-07 30.1 0.0 2.6e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Trehalase PF01204.13 AEO56949.1 - 2.7e-196 653.1 0.0 3.3e-196 652.8 0.0 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 AEO56949.1 - 4.2e-16 57.9 1.3 6.9e-16 57.2 0.9 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain DUF3405 PF11885.3 AEO56950.1 - 3.3e-199 662.2 0.0 4e-199 661.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) MFS_1 PF07690.11 AEO56951.1 - 7.3e-42 143.3 25.8 7.3e-42 143.3 17.9 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily PTR2 PF00854.16 AEO56952.1 - 2.6e-45 154.8 1.9 6.5e-45 153.5 0.9 2.0 1 1 0 1 1 1 1 POT family MFS_1 PF07690.11 AEO56952.1 - 1.5e-09 37.0 12.9 1.5e-09 37.0 9.0 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily HET PF06985.6 AEO56953.1 - 4.8e-22 78.6 0.0 9.5e-22 77.6 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MamL-1 PF09596.5 AEO56953.1 - 0.022 14.5 3.9 0.027 14.2 0.0 2.5 2 0 0 2 2 2 0 MamL-1 domain MRP-L20 PF12824.2 AEO56956.1 - 2e-54 183.9 16.7 1.1e-52 178.2 11.6 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Macoilin PF09726.4 AEO56956.1 - 0.078 11.2 7.2 0.082 11.1 5.0 1.1 1 0 0 1 1 1 0 Transmembrane protein PTRF_SDPR PF15237.1 AEO56956.1 - 0.087 12.2 2.0 0.12 11.7 1.4 1.1 1 0 0 1 1 1 0 PTRF/SDPR family Tmemb_cc2 PF10267.4 AEO56956.1 - 0.091 11.3 3.1 0.12 10.9 2.1 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Med3 PF11593.3 AEO56956.1 - 0.53 9.4 7.6 0.67 9.1 5.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Apt1 PF10351.4 AEO56956.1 - 1.9 7.2 6.9 2.4 6.8 4.8 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SSP160 PF06933.6 AEO56956.1 - 5.8 4.7 18.0 8.4 4.2 12.5 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 FYVE PF01363.16 AEO56957.1 - 0.0046 16.8 7.2 0.0046 16.8 5.0 2.8 3 0 0 3 3 3 1 FYVE zinc finger Glyco_trans_2_3 PF13632.1 AEO56958.1 - 2.7e-47 161.0 1.2 2.7e-47 161.0 0.9 2.4 2 1 1 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 AEO56958.1 - 6.7e-09 35.8 0.0 1.9e-07 31.1 0.0 2.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 AEO56958.1 - 2.1e-05 24.2 0.0 0.0001 22.0 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 2 TrbE PF11100.3 AEO56958.1 - 0.0013 18.5 3.0 0.003 17.3 2.1 1.6 1 0 0 1 1 1 1 Conjugal transfer protein TrbE Glyco_transf_21 PF13506.1 AEO56958.1 - 0.025 13.8 0.0 0.06 12.6 0.0 1.6 1 1 0 1 1 1 0 Glycosyl transferase family 21 Acyl-CoA_dh_1 PF00441.19 AEO56959.1 - 2.1e-14 53.8 0.7 3.1e-13 50.0 0.0 2.6 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 AEO56959.1 - 2e-06 27.2 0.4 3.6e-05 23.1 0.3 2.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 AEO56959.1 - 0.0078 16.4 1.5 0.29 11.3 0.0 3.3 4 0 0 4 4 4 1 Acyl-CoA dehydrogenase, C-terminal domain DUF4096 PF13340.1 AEO56959.1 - 0.082 12.7 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 Putative transposase of IS4/5 family (DUF4096) SNF2_N PF00176.18 AEO56960.1 - 9.5e-55 185.4 0.0 1.4e-54 184.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.1 AEO56960.1 - 3.9e-25 87.5 1.2 1.1e-24 86.0 0.8 1.9 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.26 AEO56960.1 - 2.9e-15 55.8 0.0 9.2e-15 54.2 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AEO56960.1 - 0.0092 15.8 0.6 0.07 12.9 0.0 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 AEO56960.1 - 0.039 12.7 0.0 0.072 11.8 0.0 1.4 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 ICL PF00463.16 AEO56961.1 - 2.5e-286 949.9 0.4 2.8e-286 949.7 0.2 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 AEO56961.1 - 6.9e-12 45.0 0.5 1.9e-11 43.6 0.0 1.9 3 0 0 3 3 3 1 Phosphoenolpyruvate phosphomutase p450 PF00067.17 AEO56963.1 - 8.6e-48 162.9 0.0 3.3e-47 161.0 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Rho_N PF07498.7 AEO56964.1 - 0.00073 19.2 0.3 0.0017 18.0 0.2 1.6 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain Nucleo_P87 PF07267.6 AEO56964.1 - 1.1 7.9 4.7 1.4 7.5 3.3 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PBP_sp32 PF07222.7 AEO56964.1 - 1.1 8.3 4.8 1.7 7.7 3.3 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Adeno_terminal PF02459.10 AEO56964.1 - 1.8 6.6 8.1 2.9 5.9 5.6 1.2 1 0 0 1 1 1 0 Adenoviral DNA terminal protein VID27 PF08553.5 AEO56964.1 - 2.1 6.4 4.6 2.8 6.0 3.2 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Myc_N PF01056.13 AEO56964.1 - 2.8 7.0 11.4 0.086 11.9 3.6 1.6 2 0 0 2 2 2 0 Myc amino-terminal region RR_TM4-6 PF06459.7 AEO56964.1 - 5.9 6.7 9.3 9.1 6.0 4.7 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 PhyH PF05721.8 AEO56965.1 - 2e-57 194.6 0.0 2.5e-57 194.3 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) RRM_1 PF00076.17 AEO56966.1 - 1.6e-38 130.1 0.2 6.9e-18 64.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO56966.1 - 9.9e-31 105.5 2.4 3.6e-15 55.7 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO56966.1 - 1.1e-13 50.8 0.0 1.3e-05 24.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 AEO56966.1 - 0.0002 21.0 1.5 0.12 12.1 0.0 2.6 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Zip PF02535.17 AEO56967.1 - 3.4 6.5 9.6 3.9 6.4 6.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter HMG14_17 PF01101.13 AEO56967.1 - 4.1 8.1 12.8 1.1 9.9 6.5 1.7 2 0 0 2 2 2 0 HMG14 and HMG17 Ribosomal_60s PF00428.14 AEO56967.1 - 7.3 7.0 11.9 17 5.8 8.3 1.7 1 1 0 1 1 1 0 60s Acidic ribosomal protein Pox_Ag35 PF03286.9 AEO56967.1 - 7.7 5.9 11.8 9.8 5.6 8.2 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF2146 PF10220.4 AEO56967.1 - 8.1 4.2 9.2 8.4 4.2 6.4 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) RabGAP-TBC PF00566.13 AEO56968.1 - 5.1e-47 160.1 0.0 2.4e-46 157.9 0.0 1.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain SHNi-TPR PF10516.4 AEO56969.1 - 4.1e-16 57.9 0.3 1.8e-15 55.8 0.2 2.3 1 0 0 1 1 1 1 SHNi-TPR TPR_11 PF13414.1 AEO56969.1 - 1.8e-07 30.7 5.9 7.8e-06 25.4 0.3 3.1 3 0 0 3 3 3 2 TPR repeat TPR_12 PF13424.1 AEO56969.1 - 1.1e-06 28.5 12.9 6.1e-05 22.8 0.2 3.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 AEO56969.1 - 5.1e-06 27.0 0.4 5.1e-06 27.0 0.3 4.0 5 1 0 5 5 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 AEO56969.1 - 0.00019 21.7 0.7 0.00019 21.7 0.5 2.5 3 0 0 3 3 2 1 Tetratricopeptide repeat Apc3 PF12895.2 AEO56969.1 - 0.00022 21.2 0.3 0.013 15.6 0.0 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.7 AEO56969.1 - 0.00071 19.3 1.8 0.0019 17.9 1.3 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.1 AEO56969.1 - 0.0061 16.6 1.7 0.16 12.2 0.0 3.6 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 AEO56969.1 - 0.022 14.6 2.0 0.022 14.6 1.4 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 AEO56969.1 - 0.058 13.0 1.8 0.21 11.2 0.9 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 AEO56969.1 - 0.37 10.7 3.2 7.5 6.6 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 AEO56969.1 - 8.3 7.3 11.1 0.97 10.2 0.6 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Flavoprotein PF02441.14 AEO56970.1 - 6.5e-42 142.2 0.3 9.3e-42 141.7 0.2 1.2 1 0 0 1 1 1 1 Flavoprotein Sec1 PF00995.18 AEO56972.1 - 7e-153 510.2 0.0 8.3e-153 510.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Chitin_synth_1 PF01644.12 AEO56973.1 - 2e-81 271.5 0.3 3e-81 271.0 0.2 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 AEO56973.1 - 1.3e-32 111.3 0.0 2.4e-32 110.4 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 AEO56973.1 - 1e-21 76.9 8.0 3.1e-18 65.4 0.0 2.3 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 AEO56973.1 - 1.6e-07 31.2 10.6 3.4e-07 30.1 5.6 2.8 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 AEO56973.1 - 1.2e-06 28.5 0.0 5.4e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 DUF3602 PF12223.3 AEO56974.1 - 1.6e-17 63.6 9.7 4.6e-15 55.7 3.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) GTP1_OBG PF01018.17 AEO56974.1 - 3 7.4 6.0 14 5.2 0.0 2.9 1 1 1 3 3 3 0 GTP1/OBG Actin PF00022.14 AEO56975.1 - 1.3e-132 441.9 0.0 1.5e-132 441.7 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 AEO56975.1 - 0.003 16.2 0.0 0.94 8.0 0.0 2.6 2 1 0 2 2 2 2 MreB/Mbl protein Methyltransf_23 PF13489.1 AEO56976.1 - 3.4e-23 82.1 0.0 5.8e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO56976.1 - 2.6e-13 49.8 0.0 1.6e-12 47.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO56976.1 - 3e-12 47.1 0.1 2e-11 44.4 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO56976.1 - 1.5e-11 44.6 0.0 3e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO56976.1 - 7.2e-11 42.4 0.0 4e-10 40.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO56976.1 - 2.2e-07 31.1 0.0 3.8e-06 27.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 AEO56976.1 - 3.1e-05 23.2 0.0 4.8e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 AEO56976.1 - 5.3e-05 23.2 0.0 0.00019 21.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 AEO56976.1 - 0.00019 20.5 0.0 0.00058 18.9 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 AEO56976.1 - 0.00025 20.4 0.0 0.00058 19.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 AEO56976.1 - 0.0014 18.6 0.0 0.0026 17.7 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 AEO56976.1 - 0.0038 16.6 0.0 0.0072 15.7 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.13 AEO56976.1 - 0.0086 15.2 0.0 0.044 12.8 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Met_10 PF02475.11 AEO56976.1 - 0.045 13.3 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein CMAS PF02353.15 AEO56976.1 - 0.095 11.7 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase TehB PF03848.9 AEO56976.1 - 0.12 11.5 0.0 0.35 9.9 0.0 1.6 1 1 0 1 1 1 0 Tellurite resistance protein TehB GHMP_kinases_N PF00288.21 AEO56978.1 - 1.7e-12 47.1 0.0 3.3e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 AEO56978.1 - 6.1e-06 26.3 0.0 1.4e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal IFRD PF05004.8 AEO56980.1 - 2.4e-27 95.8 2.3 3.2e-27 95.4 1.6 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) HEAT_2 PF13646.1 AEO56980.1 - 0.037 14.3 0.1 3.1 8.1 0.0 2.4 1 1 0 1 1 1 0 HEAT repeats Cnd3 PF12719.2 AEO56980.1 - 0.064 12.2 0.1 0.099 11.6 0.0 1.4 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.1 AEO56980.1 - 0.064 13.7 0.4 62 4.2 0.0 4.0 2 2 2 4 4 4 0 HEAT-like repeat Herpes_capsid PF06112.6 AEO56980.1 - 3.4 7.7 8.3 8.3 6.4 5.3 2.0 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein FHA PF00498.21 AEO56981.1 - 3.2e-14 52.7 0.0 6.6e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 FHA domain WD40 PF00400.27 AEO56982.1 - 3.5e-49 163.0 19.6 2e-12 46.4 0.2 7.4 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 AEO56982.1 - 5.7e-08 31.3 4.3 0.049 11.7 0.1 4.9 2 1 1 5 5 5 3 Nucleoporin Nup120/160 DUF3312 PF11768.3 AEO56982.1 - 0.0013 17.0 0.0 0.0032 15.7 0.0 1.6 2 1 0 2 2 2 1 Protein of unknown function (DUF3312) DUF1513 PF07433.6 AEO56982.1 - 0.0015 17.4 0.6 4.8 5.9 0.0 3.5 1 1 2 3 3 3 2 Protein of unknown function (DUF1513) Hira PF07569.6 AEO56982.1 - 0.088 12.0 0.4 5 6.2 0.0 2.8 1 1 2 3 3 3 0 TUP1-like enhancer of split HEAT PF02985.17 AEO56983.1 - 1.8e-12 46.1 1.3 0.022 14.8 0.0 5.7 5 0 0 5 5 5 4 HEAT repeat Pkinase PF00069.20 AEO56983.1 - 1.3e-05 24.5 0.0 2.3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HEAT_2 PF13646.1 AEO56983.1 - 6.1e-05 23.2 0.1 0.047 13.9 0.0 4.1 2 1 2 4 4 4 2 HEAT repeats Pkinase_Tyr PF07714.12 AEO56983.1 - 0.00028 20.0 0.0 0.00053 19.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_EZ PF13513.1 AEO56983.1 - 0.00028 21.2 0.0 0.93 10.0 0.0 3.5 2 0 0 2 2 2 2 HEAT-like repeat Kinase-like PF14531.1 AEO56983.1 - 0.0013 17.7 0.0 0.0021 17.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Cnd1 PF12717.2 AEO56983.1 - 0.0034 17.2 0.0 0.0086 15.9 0.0 1.7 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 AEO56983.1 - 0.035 12.4 0.0 0.091 11.0 0.0 1.5 1 1 0 1 1 1 0 Adaptin N terminal region Aconitase PF00330.15 AEO56986.1 - 1.2e-154 515.2 0.0 2.7e-154 514.0 0.0 1.5 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 AEO56986.1 - 6.2e-36 123.3 0.0 1.1e-35 122.6 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.8 AEO56986.1 - 0.1 11.1 0.0 0.16 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Rad52_Rad22 PF04098.10 AEO56987.1 - 2.2e-58 196.3 0.0 3.8e-58 195.5 0.0 1.4 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein F-protein PF00469.15 AEO56987.1 - 0.046 13.0 0.5 1.5 8.1 0.0 2.2 2 0 0 2 2 2 0 Negative factor, (F-Protein) or Nef TFIIA PF03153.8 AEO56987.1 - 0.11 12.3 12.1 0.17 11.7 8.4 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDK5_activator PF03261.10 AEO56987.1 - 0.97 8.7 7.7 1.4 8.1 5.3 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein PAT1 PF09770.4 AEO56987.1 - 3.6 5.7 18.7 5.1 5.2 13.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hid1 PF12722.2 AEO56987.1 - 3.6 5.1 7.0 4.8 4.7 4.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Cut8_C PF08559.5 AEO56988.1 - 1.2e-48 164.5 0.0 1.6e-48 164.1 0.0 1.2 1 0 0 1 1 1 1 Cut8 six-helix bundle Cut8_M PF14483.1 AEO56988.1 - 5.3e-17 61.3 0.7 1.1e-16 60.2 0.5 1.6 1 0 0 1 1 1 1 Cut8 dimerisation domain Cut8_N PF14482.1 AEO56988.1 - 1.1e-08 34.9 2.0 2.2e-08 33.9 0.9 1.9 2 0 0 2 2 2 1 Cut8 proteasome-binding domain RRM_1 PF00076.17 AEO56989.1 - 8.7e-21 73.3 0.1 8.8e-14 50.8 0.0 4.0 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO56989.1 - 5.8e-19 67.8 0.0 6.6e-10 38.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO56989.1 - 6.9e-08 32.2 0.0 0.0013 18.5 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BUD22 PF09073.5 AEO56989.1 - 0.0019 17.3 31.2 0.0019 17.3 21.6 4.1 4 0 0 4 4 4 1 BUD22 API5 PF05918.6 AEO56989.1 - 1.2 7.5 19.4 2 6.7 13.5 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) SOBP PF15279.1 AEO56989.1 - 8.5 6.6 25.1 8.8 6.6 0.8 2.1 2 0 0 2 2 2 0 Sine oculis-binding protein ZZ PF00569.12 AEO56990.1 - 3.1e-18 65.0 64.1 1.1e-06 28.0 3.8 4.4 4 0 0 4 4 4 4 Zinc finger, ZZ type UPF0052 PF01933.13 AEO56991.1 - 4.7e-22 78.6 0.0 6.2e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 UPF0052 PF01933.13 AEO56992.1 - 0.0002 20.7 0.0 0.00026 20.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 RIIa PF02197.12 AEO56992.1 - 0.045 13.1 0.1 0.079 12.4 0.1 1.4 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit Btz PF09405.5 AEO56993.1 - 3.9e-28 98.1 3.7 6.7e-28 97.3 1.6 2.2 1 1 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding Asp PF00026.18 AEO56994.1 - 3.2e-50 171.1 0.3 6e-50 170.2 0.2 1.4 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 AEO56994.1 - 1e-06 29.1 0.0 0.013 15.9 0.0 2.3 2 0 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 AEO56994.1 - 0.021 14.7 0.1 0.15 11.9 0.1 2.2 1 1 0 1 1 1 0 Xylanase inhibitor N-terminal NKWYS PF10364.4 AEO56994.1 - 0.12 12.0 0.2 0.22 11.2 0.1 1.3 1 0 0 1 1 1 0 Putative capsular polysaccharide synthesis protein Aminotran_4 PF01063.14 AEO56995.1 - 3.7e-25 88.7 0.0 1.1e-24 87.1 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class IV TPR_11 PF13414.1 AEO56996.1 - 2.9e-57 190.2 31.8 2.3e-15 55.9 0.7 6.7 4 2 3 7 7 7 7 TPR repeat TPR_1 PF00515.23 AEO56996.1 - 1.1e-44 148.3 34.8 2.1e-06 27.0 0.1 11.4 10 1 1 11 11 11 10 Tetratricopeptide repeat TPR_2 PF07719.12 AEO56996.1 - 1.7e-40 133.6 34.0 1.9e-05 24.1 0.1 11.5 10 1 1 11 11 11 10 Tetratricopeptide repeat TPR_12 PF13424.1 AEO56996.1 - 3.1e-27 94.3 25.2 1.7e-07 31.0 0.0 7.4 2 2 6 8 8 8 7 Tetratricopeptide repeat TPR_17 PF13431.1 AEO56996.1 - 1.7e-26 90.1 11.2 0.00099 19.1 0.0 8.9 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_16 PF13432.1 AEO56996.1 - 5.4e-24 84.2 23.2 6.6e-06 26.6 0.8 7.2 6 1 1 7 7 6 5 Tetratricopeptide repeat TPR_8 PF13181.1 AEO56996.1 - 6.6e-18 63.0 23.2 0.0029 17.2 0.1 10.1 9 1 1 10 10 10 4 Tetratricopeptide repeat TPR_9 PF13371.1 AEO56996.1 - 6.7e-15 54.7 12.4 0.00019 21.2 0.4 7.0 3 2 5 8 8 8 5 Tetratricopeptide repeat Apc3 PF12895.2 AEO56996.1 - 1.8e-14 53.6 17.2 0.00041 20.4 0.2 5.7 3 1 2 5 5 5 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 AEO56996.1 - 4.7e-13 48.5 20.5 0.035 14.7 0.6 10.2 3 3 8 11 11 11 5 Tetratricopeptide repeat TPR_19 PF14559.1 AEO56996.1 - 2e-12 47.2 22.9 4.5e-06 26.9 0.7 7.3 4 2 3 7 7 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 AEO56996.1 - 4.2e-12 44.8 21.8 0.04 13.7 0.2 9.9 9 1 1 10 10 10 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 AEO56996.1 - 4.4e-07 29.0 5.7 0.096 11.9 0.0 5.8 6 0 0 6 6 6 2 SHNi-TPR DUF3856 PF12968.2 AEO56996.1 - 0.00011 22.0 10.7 3.1 7.6 0.0 5.9 4 2 1 5 5 5 3 Domain of Unknown Function (DUF3856) TPR_10 PF13374.1 AEO56996.1 - 0.0003 20.6 8.2 1.6 8.7 0.5 5.9 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 AEO56996.1 - 0.008 16.5 22.6 4.6 7.9 0.4 9.2 10 1 0 10 10 8 1 Tetratricopeptide repeat MAS20 PF02064.10 AEO56996.1 - 0.01 15.7 5.3 16 5.4 0.9 4.2 3 2 0 3 3 3 0 MAS20 protein import receptor Med3 PF11593.3 AEO56996.1 - 0.021 14.1 6.5 0.057 12.6 4.5 1.6 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Ycf1 PF05758.7 AEO56996.1 - 0.033 11.9 1.0 0.043 11.5 0.7 1.2 1 0 0 1 1 1 0 Ycf1 TRAPPC9-Trs120 PF08626.6 AEO56996.1 - 0.045 11.1 0.0 4.3 4.5 0.0 2.1 2 0 0 2 2 2 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Podoplanin PF05808.6 AEO56996.1 - 0.8 9.2 4.0 1.4 8.4 2.8 1.3 1 0 0 1 1 1 0 Podoplanin NARP1 PF12569.3 AEO56996.1 - 2.5 6.7 33.6 0.31 9.7 0.4 4.8 3 2 2 5 5 5 0 NMDA receptor-regulated protein 1 Syntaxin PF00804.20 AEO56997.1 - 4.1e-08 33.3 5.8 4.1e-08 33.3 4.0 2.9 2 1 1 3 3 3 1 Syntaxin SNARE PF05739.14 AEO56997.1 - 0.00016 21.2 7.3 0.00016 21.2 5.1 2.4 2 0 0 2 2 2 1 SNARE domain DUF3018 PF11455.3 AEO56997.1 - 0.065 13.1 2.5 0.26 11.2 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3018) Syntaxin_2 PF14523.1 AEO56997.1 - 6.8 6.7 14.5 4.8 7.2 7.1 2.3 2 0 0 2 2 2 0 Syntaxin-like protein Brix PF04427.13 AEO56998.1 - 1.3e-45 155.4 0.2 1.6e-45 155.1 0.2 1.1 1 0 0 1 1 1 1 Brix domain UPF1_Zn_bind PF09416.5 AEO56999.1 - 6e-72 240.2 2.4 9.6e-72 239.5 1.7 1.3 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) Ribosomal_S27e PF01667.12 AEO56999.1 - 0.37 10.3 5.3 0.37 10.3 1.4 2.3 2 0 0 2 2 2 0 Ribosomal protein S27 zf-UBP PF02148.14 AEO56999.1 - 0.49 10.5 6.7 1.1 9.4 4.7 1.6 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein AhpC-TSA_2 PF13911.1 AEO57000.1 - 5.6e-17 61.7 0.0 1.8e-16 60.1 0.0 1.7 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 AEO57000.1 - 0.00044 19.9 0.0 0.001 18.7 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 AEO57000.1 - 0.0087 15.6 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 Redoxin DUF2580 PF10824.3 AEO57001.1 - 1.6 9.1 6.2 15 5.9 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2580) Aminotran_4 PF01063.14 AEO57002.1 - 3.2e-24 85.6 0.0 5e-24 85.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class IV CTP_transf_2 PF01467.21 AEO57005.1 - 1.2e-17 64.4 0.0 1.5e-15 57.5 0.0 2.5 2 0 0 2 2 2 2 Cytidylyltransferase WD40 PF00400.27 AEO57006.1 - 5.7e-25 86.2 0.1 0.00012 21.8 0.0 5.3 6 0 0 6 6 6 4 WD domain, G-beta repeat Peptidase_S9 PF00326.16 AEO57006.1 - 0.056 12.6 0.2 3.5 6.7 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family AAT PF03417.11 AEO57007.1 - 2.9e-14 53.0 0.0 4.6e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase COPIIcoated_ERV PF07970.7 AEO57008.1 - 7.3e-36 123.8 0.0 9.9e-36 123.4 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 AEO57008.1 - 4.9e-21 74.5 0.0 7.5e-21 73.9 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Gln-synt_C PF00120.19 AEO57009.1 - 1e-55 188.7 0.0 1.5e-55 188.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.9 AEO57009.1 - 1.1e-28 100.6 0.4 3.3e-28 99.0 0.0 1.9 2 0 0 2 2 2 1 Amidohydrolase Glyco_hydro_76 PF03663.9 AEO57010.1 - 6.6e-152 506.1 13.7 8.3e-152 505.8 9.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 AEO57010.1 - 0.01 14.9 8.7 0.36 9.8 0.1 3.1 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 Colipase_C PF02740.9 AEO57010.1 - 0.064 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Colipase, C-terminal domain zf-MYND PF01753.13 AEO57011.1 - 8.2e-09 35.1 8.2 1.2e-08 34.6 5.7 1.2 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.11 AEO57011.1 - 2.1 8.0 5.6 0.36 10.5 0.9 1.9 2 0 0 2 2 2 0 HIT zinc finger 2OG-FeII_Oxy_3 PF13640.1 AEO57012.1 - 3.1e-12 46.8 0.1 7.4e-12 45.6 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 AEO57012.1 - 0.00013 21.5 0.0 0.00033 20.2 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ABC1 PF03109.11 AEO57013.1 - 3.4e-31 107.6 0.0 5.4e-31 107.0 0.0 1.3 1 0 0 1 1 1 1 ABC1 family Peptidase_C6 PF00851.13 AEO57015.1 - 0.003 16.2 0.1 0.0051 15.5 0.1 1.2 1 0 0 1 1 1 1 Helper component proteinase AAA_17 PF13207.1 AEO57016.1 - 1.8e-07 31.9 0.0 1.7e-06 28.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AEO57016.1 - 1.9e-06 28.2 0.0 3.1e-05 24.2 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AEO57016.1 - 8e-06 25.7 1.3 0.0004 20.2 0.9 2.4 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 AEO57016.1 - 2.3e-05 24.0 0.0 3.2e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.7 AEO57016.1 - 9.2e-05 21.6 0.1 0.0021 17.2 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin T2SE PF00437.15 AEO57016.1 - 0.0021 17.0 0.0 0.019 13.9 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_16 PF13191.1 AEO57016.1 - 0.0046 16.9 0.1 0.0093 15.9 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 AEO57016.1 - 0.0092 16.1 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 AEO57016.1 - 0.013 14.7 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Thymidylate_kin PF02223.12 AEO57016.1 - 0.02 14.2 0.0 0.16 11.3 0.0 2.0 2 0 0 2 2 2 0 Thymidylate kinase NACHT PF05729.7 AEO57016.1 - 0.027 14.1 0.0 0.05 13.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain cobW PF02492.14 AEO57016.1 - 0.062 12.7 0.1 0.097 12.1 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.17 AEO57016.1 - 0.067 12.0 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_28 PF13521.1 AEO57016.1 - 0.072 13.0 0.3 0.22 11.4 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 AEO57016.1 - 0.088 12.5 0.1 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) 6PF2K PF01591.13 AEO57016.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.1 1 0 0 1 1 1 0 6-phosphofructo-2-kinase NTPase_1 PF03266.10 AEO57016.1 - 0.15 11.7 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 NTPase Viral_helicase1 PF01443.13 AEO57016.1 - 0.16 11.4 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ArgK PF03308.11 AEO57016.1 - 0.18 10.5 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 ArgK protein AAA_19 PF13245.1 AEO57016.1 - 0.2 11.4 5.6 0.064 13.0 0.6 2.5 2 1 0 2 2 2 0 Part of AAA domain Mus7 PF09462.5 AEO57017.1 - 0.1 11.4 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Mus7/MMS22 family PBP1_TM PF14812.1 AEO57017.1 - 0.12 12.6 3.1 1.4 9.2 0.1 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PRELI PF04707.9 AEO57018.1 - 3.6e-42 143.5 0.2 4.3e-42 143.3 0.2 1.0 1 0 0 1 1 1 1 PRELI-like family GATase_3 PF07685.9 AEO57018.1 - 0.022 14.3 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Peptidase_M24 PF00557.19 AEO57019.1 - 1.9e-46 158.3 0.1 2.4e-46 157.9 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF3292 PF11696.3 AEO57019.1 - 4.5 5.0 6.2 6.3 4.5 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) DnaJ PF00226.26 AEO57020.1 - 3.9e-21 74.5 0.5 6.4e-21 73.8 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain Porin_3 PF01459.17 AEO57021.1 - 1.3e-66 224.6 8.4 1.5e-66 224.5 5.8 1.0 1 0 0 1 1 1 1 Eukaryotic porin Asn_synthase PF00733.16 AEO57022.1 - 2.3e-68 230.4 0.0 3.3e-68 229.9 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 AEO57022.1 - 1.4e-37 128.2 0.0 2.6e-37 127.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 AEO57022.1 - 6e-29 100.6 0.0 1.7e-28 99.2 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 AEO57022.1 - 4.4e-09 35.8 0.0 9.3e-09 34.8 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.12 AEO57022.1 - 0.00034 19.5 0.0 0.0021 17.0 0.0 1.9 1 1 0 1 1 1 1 NAD synthase GATase_2 PF00310.16 AEO57022.1 - 0.0012 17.6 0.0 0.12 11.0 0.0 2.7 1 1 2 3 3 3 1 Glutamine amidotransferases class-II QueC PF06508.8 AEO57022.1 - 0.18 11.0 0.0 0.34 10.1 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC UQ_con PF00179.21 AEO57023.1 - 2.7e-49 166.1 0.1 3.1e-49 166.0 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AEO57023.1 - 0.00054 19.7 0.0 0.00074 19.2 0.0 1.3 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 AEO57023.1 - 0.067 13.0 1.2 0.12 12.2 0.8 1.8 1 1 0 1 1 1 0 RWD domain Pex19 PF04614.7 AEO57024.1 - 1.1e-73 247.9 12.9 1.1e-73 247.9 8.9 1.6 2 0 0 2 2 2 1 Pex19 protein family Acetyltransf_6 PF13480.1 AEO57024.1 - 0.31 10.9 1.4 1.4 8.8 0.0 2.4 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain FliE PF02049.13 AEO57024.1 - 0.5 10.4 8.1 2.2 8.3 0.9 3.5 2 1 1 3 3 3 0 Flagellar hook-basal body complex protein FliE TipAS PF07739.8 AEO57024.1 - 1.3 9.3 9.6 0.94 9.8 0.1 3.5 2 2 1 3 3 3 0 TipAS antibiotic-recognition domain Gluconate_2-dh3 PF13618.1 AEO57024.1 - 2 8.5 10.1 35 4.5 0.1 3.1 1 1 1 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 FUSC PF04632.7 AEO57025.1 - 6.5 5.0 11.2 7.2 4.9 7.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Formyl_trans_N PF00551.14 AEO57027.1 - 2.4e-19 69.5 0.0 4.6e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase Ribosomal_60s PF00428.14 AEO57027.1 - 1.4 9.3 5.5 11 6.5 0.0 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein HABP4_PAI-RBP1 PF04774.10 AEO57028.1 - 8.3e-05 23.0 1.7 0.00013 22.4 1.2 1.3 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family HD-ZIP_N PF04618.7 AEO57028.1 - 0.003 18.0 0.2 0.003 18.0 0.2 1.2 1 0 0 1 1 1 1 HD-ZIP protein N terminus CIAPIN1 PF05093.8 AEO57029.1 - 3.5e-35 120.0 4.3 5.5e-35 119.4 3.0 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Dmrt1 PF12374.3 AEO57029.1 - 4.9 7.5 6.2 3.4 8.0 2.4 2.1 2 0 0 2 2 2 0 Double-sex mab3 related transcription factor 1 Peptidase_S10 PF00450.17 AEO57030.1 - 2.2e-112 376.2 0.0 2.9e-112 375.8 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 AEO57030.1 - 0.00037 20.4 0.0 0.0012 18.7 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF3099 PF11298.3 AEO57030.1 - 0.12 12.1 0.1 0.31 10.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3099) DHO_dh PF01180.16 AEO57031.1 - 9.3e-19 67.4 0.0 1.3e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase DHquinase_I PF01487.10 AEO57032.1 - 6.5e-58 196.0 0.0 8.8e-58 195.5 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase Fungal_trans PF04082.13 AEO57033.1 - 5.4e-28 97.5 0.0 9e-28 96.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO57033.1 - 5.5e-06 26.1 15.4 9.6e-06 25.4 10.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 AEO57034.1 - 6.2e-07 28.4 22.7 6.2e-07 28.4 15.7 4.7 3 2 1 4 4 4 3 Major Facilitator Superfamily MFS_1 PF07690.11 AEO57035.1 - 6.2e-31 107.3 56.8 6.2e-31 107.3 39.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO57035.1 - 6.4e-11 41.4 14.8 6.4e-11 41.4 10.3 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter Amidohydro_2 PF04909.9 AEO57036.1 - 1.2e-06 28.3 0.2 3.8e-06 26.6 0.1 1.8 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 AEO57036.1 - 4.4e-05 23.6 1.0 6.1e-05 23.1 0.7 1.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 AEO57036.1 - 0.001 18.7 0.1 0.0014 18.3 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family CoA_binding_2 PF13380.1 AEO57036.1 - 0.0018 18.4 0.1 0.13 12.4 0.0 2.2 1 1 1 2 2 2 1 CoA binding domain Spc97_Spc98 PF04130.8 AEO57037.1 - 5.3e-119 397.9 0.9 9.9e-119 397.0 0.0 1.8 2 0 0 2 2 2 1 Spc97 / Spc98 family Viral_env_E26 PF11050.3 AEO57037.1 - 0.086 12.0 2.2 0.2 10.8 1.5 1.5 1 0 0 1 1 1 0 Virus envelope protein E26 DUF3439 PF11921.3 AEO57037.1 - 7.6 6.3 14.7 19 4.9 10.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SAGA-Tad1 PF12767.2 AEO57038.1 - 1.9e-60 204.6 0.0 2.4e-60 204.3 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit MRC1 PF09444.5 AEO57039.1 - 2e-44 151.4 23.9 2e-44 151.4 16.6 7.3 6 2 0 7 7 7 1 MRC1-like domain Drf_GBD PF06371.8 AEO57039.1 - 1 8.7 3.6 2.7 7.2 2.5 1.7 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain DUF3439 PF11921.3 AEO57039.1 - 5.9 6.6 9.7 17 5.2 6.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Pkinase PF00069.20 AEO57040.1 - 1.7e-46 158.4 0.0 1.3e-45 155.6 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO57040.1 - 2.4e-24 85.8 0.0 4e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO57040.1 - 0.00027 20.0 0.0 0.0009 18.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like YHS PF04945.8 AEO57040.1 - 0.046 13.5 0.1 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 YHS domain Med1 PF10744.4 AEO57041.1 - 6.1e-31 107.5 0.0 2.2e-20 72.7 0.0 2.3 2 0 0 2 2 2 2 Mediator of RNA polymerase II transcription subunit 1 SlyX PF04102.7 AEO57042.1 - 0.031 14.6 7.7 0.2 12.0 0.3 3.9 3 1 2 5 5 5 0 SlyX SPATA24 PF15175.1 AEO57042.1 - 0.041 13.5 0.4 0.11 12.1 0.2 1.6 1 1 0 1 1 1 0 Spermatogenesis-associated protein 24 FlgN PF05130.7 AEO57042.1 - 0.23 11.7 14.1 0.055 13.7 4.5 2.7 2 1 1 3 3 3 0 FlgN protein THOC7 PF05615.8 AEO57042.1 - 0.47 10.7 7.0 4 7.6 4.9 2.2 1 1 1 2 2 2 0 Tho complex subunit 7 DUF445 PF04286.7 AEO57042.1 - 0.81 9.1 4.8 1.1 8.7 3.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF445) YicC_N PF03755.8 AEO57042.1 - 3.7 7.4 10.3 0.52 10.2 0.8 2.6 1 1 2 3 3 3 0 YicC-like family, N-terminal region LRR_6 PF13516.1 AEO57043.1 - 1.2e-05 24.8 1.9 43 4.6 0.0 6.9 7 0 0 7 7 7 1 Leucine Rich repeat LRR_4 PF12799.2 AEO57043.1 - 0.0027 17.2 1.7 0.45 10.2 0.1 4.3 5 0 0 5 5 5 1 Leucine Rich repeats (2 copies) Ribosomal_L37 PF08561.5 AEO57043.1 - 0.91 9.1 0.0 0.91 9.1 0.0 3.0 2 1 0 2 2 2 0 Mitochondrial ribosomal protein L37 Ribosomal_L18p PF00861.17 AEO57044.1 - 1.2e-39 135.1 0.1 1.2e-39 135.1 0.1 1.8 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 AEO57044.1 - 5.8e-34 116.5 7.1 5.8e-34 116.5 4.9 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region SLT_2 PF13406.1 AEO57044.1 - 9.4 5.0 7.6 2.7 6.8 0.5 2.2 2 0 0 2 2 2 0 Transglycosylase SLT domain HAD_2 PF13419.1 AEO57045.1 - 1.9e-15 57.5 0.0 1.1e-14 55.0 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 AEO57045.1 - 0.0011 18.6 0.1 0.0026 17.4 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like MCM PF00493.18 AEO57046.1 - 8.3e-141 468.5 0.0 8.3e-141 468.5 0.0 1.6 2 0 0 2 2 2 1 MCM2/3/5 family MCM2_N PF12619.3 AEO57046.1 - 7.8e-32 110.4 39.7 7.8e-32 110.4 27.5 2.0 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 AEO57046.1 - 4.5e-21 75.5 0.1 1.1e-20 74.3 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 AEO57046.1 - 6.8e-08 31.9 0.0 5.8e-06 25.6 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 AEO57046.1 - 2.3e-06 27.3 0.0 4.7e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 AEO57046.1 - 0.0019 17.8 0.1 0.017 14.7 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 AEO57046.1 - 0.002 17.6 0.2 0.014 14.8 0.1 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain zf-TFIIB PF13453.1 AEO57046.1 - 0.065 12.4 1.2 0.15 11.3 0.8 1.6 1 0 0 1 1 1 0 Transcription factor zinc-finger zf-UBR PF02207.15 AEO57047.1 - 6.8e-17 60.9 4.3 6.8e-17 60.9 3.0 3.1 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) ATG2_CAD PF13329.1 AEO57048.1 - 9.1e-47 158.5 0.0 1.7e-46 157.6 0.0 1.5 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.6 AEO57048.1 - 5.1e-30 103.5 1.0 1.4e-29 102.1 0.2 2.2 2 0 0 2 2 2 1 ATG C terminal domain Chorein_N PF12624.2 AEO57048.1 - 0.044 13.3 0.0 1.2 8.7 0.0 2.5 2 0 0 2 2 2 0 N-terminal region of Chorein, a TM vesicle-mediated sorter Amino_oxidase PF01593.19 AEO57049.1 - 6.9e-49 167.1 0.8 4.5e-47 161.1 0.5 2.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 AEO57049.1 - 4.2e-16 58.7 0.1 9.1e-16 57.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 AEO57049.1 - 3.4e-07 29.4 0.0 0.00032 19.6 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 AEO57049.1 - 6.8e-06 25.9 0.2 0.0043 16.8 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 AEO57049.1 - 3e-05 24.1 0.1 0.00048 20.2 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AEO57049.1 - 3.3e-05 24.2 0.3 7.3e-05 23.0 0.1 1.7 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 AEO57049.1 - 0.00024 20.0 0.3 0.0017 17.2 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 AEO57049.1 - 0.00028 19.4 0.1 0.005 15.3 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 AEO57049.1 - 0.00036 20.4 0.1 0.011 15.6 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 AEO57049.1 - 0.00056 19.0 0.0 0.00094 18.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 AEO57049.1 - 0.0021 17.1 0.2 0.0034 16.5 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 AEO57049.1 - 0.004 16.3 0.1 0.0066 15.5 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Rossmann-like PF10727.4 AEO57049.1 - 0.014 15.0 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 Rossmann-like domain 3HCDH_N PF02737.13 AEO57049.1 - 0.018 14.6 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2020 PF09449.5 AEO57049.1 - 0.072 12.7 0.0 0.16 11.6 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF2020) UDPG_MGDP_dh_N PF03721.9 AEO57049.1 - 0.13 11.5 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Acyl-CoA_dh_1 PF00441.19 AEO57050.1 - 9.8e-35 119.8 2.2 1.4e-34 119.3 1.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.23 AEO57050.1 - 2.4e-20 72.1 0.1 6.7e-20 70.6 0.1 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.14 AEO57050.1 - 1.5e-16 59.5 0.7 4.1e-16 58.2 0.5 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 AEO57050.1 - 1.2e-07 32.2 0.1 1.1e-06 29.2 0.0 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 AEO57050.1 - 0.00085 19.5 0.2 0.002 18.3 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain SAE2 PF08573.5 AEO57052.1 - 3.1e-29 101.5 0.4 1e-28 99.8 0.0 2.2 2 0 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus UCH PF00443.24 AEO57053.1 - 1.4e-48 165.3 0.0 4.6e-48 163.6 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AEO57053.1 - 1.5e-19 70.5 0.0 3.1e-19 69.5 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Glyco_transf_8 PF01501.15 AEO57054.1 - 2.4e-20 72.9 0.0 1.9e-16 60.1 0.0 2.7 2 1 0 2 2 2 2 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 AEO57054.1 - 0.0078 15.5 0.0 0.017 14.4 0.0 1.5 1 1 0 1 1 1 1 Mannosyltransferase putative Mucin PF01456.12 AEO57054.1 - 0.093 12.5 19.3 0.19 11.5 13.4 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Pex14_N PF04695.8 AEO57054.1 - 0.14 12.2 0.5 0.3 11.1 0.3 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Sporozoite_P67 PF05642.6 AEO57054.1 - 0.27 9.0 9.1 0.52 8.1 6.3 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF3439 PF11921.3 AEO57054.1 - 1.6 8.4 14.7 3.1 7.5 10.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.6 AEO57054.1 - 1.9 6.4 18.6 2.6 5.8 12.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 RNase_T PF00929.19 AEO57055.1 - 4.8e-08 33.4 0.0 0.0017 18.6 0.0 2.4 2 0 0 2 2 2 2 Exonuclease Band_7 PF01145.20 AEO57056.1 - 3.8e-25 88.8 4.3 6.6e-25 88.0 3.0 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family DUF2884 PF11101.3 AEO57056.1 - 0.0071 15.7 1.8 0.01 15.2 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2884) UcrQ PF02939.11 AEO57057.1 - 8.4e-33 112.0 0.4 1e-32 111.7 0.2 1.0 1 0 0 1 1 1 1 UcrQ family NIF PF03031.13 AEO57058.1 - 6.7e-51 172.1 0.0 9.4e-51 171.6 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Calici_coat PF00915.15 AEO57058.1 - 0.044 12.7 0.0 0.07 12.0 0.0 1.2 1 0 0 1 1 1 0 Calicivirus coat protein Pol_alpha_B_N PF08418.5 AEO57058.1 - 4.7 6.6 6.2 8 5.9 4.3 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF1761 PF08570.5 AEO57059.1 - 4e-21 75.3 3.1 4.6e-21 75.1 2.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) Ribosomal_L7Ae PF01248.21 AEO57060.1 - 4.5e-16 58.1 0.8 5.3e-15 54.7 0.6 2.4 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Dynactin_p62 PF05502.8 AEO57060.1 - 0.094 11.4 3.6 0.16 10.6 2.5 1.3 1 0 0 1 1 1 0 Dynactin p62 family IF-2B PF01008.12 AEO57061.1 - 1.5e-36 125.9 0.0 3.9e-36 124.4 0.0 1.6 1 1 0 1 1 1 1 Initiation factor 2 subunit family Cep57_MT_bd PF06657.8 AEO57061.1 - 0.16 11.9 0.0 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 DUF4646 PF15496.1 AEO57062.1 - 1.4e-05 25.1 0.4 0.00015 21.7 0.2 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4646) DUF3375 PF11855.3 AEO57062.1 - 5.4e-05 22.1 1.9 5.4e-05 22.1 1.3 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3375) DUF4207 PF13904.1 AEO57062.1 - 0.0014 18.0 20.2 0.0014 18.0 14.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4207) CAF-1_p150 PF11600.3 AEO57062.1 - 0.006 15.9 24.3 0.006 15.9 16.9 2.4 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Acetyltransf_1 PF00583.19 AEO57063.1 - 1.2e-14 54.0 0.1 2.4e-14 53.1 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 AEO57063.1 - 2.4e-06 27.2 0.1 4.7e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 AEO57063.1 - 0.0013 18.8 0.0 0.0026 17.8 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 AEO57063.1 - 0.0063 16.6 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 AEO57063.1 - 0.023 14.5 0.1 0.04 13.7 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 AEO57063.1 - 0.045 13.6 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain adh_short PF00106.20 AEO57064.1 - 9.1e-33 113.5 2.2 1.5e-32 112.8 1.5 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO57064.1 - 3.5e-22 79.3 0.1 4.3e-21 75.7 0.1 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO57064.1 - 9.7e-17 61.2 0.3 1.4e-16 60.6 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 AEO57064.1 - 2e-07 30.7 0.1 8.8e-07 28.5 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 AEO57064.1 - 0.078 11.8 0.1 0.77 8.6 0.0 2.3 2 1 0 2 2 2 0 Male sterility protein DUF1776 PF08643.5 AEO57064.1 - 0.18 10.9 0.0 0.25 10.4 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Yae1_N PF09811.4 AEO57065.1 - 5e-09 35.5 5.9 5e-09 35.5 4.1 2.1 2 0 0 2 2 2 1 Essential protein Yae1, N terminal CI-B14_5a PF07347.7 AEO57066.1 - 0.0031 17.2 0.0 0.0067 16.1 0.0 1.6 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) AhpC-TSA PF00578.16 AEO57067.1 - 2.5e-23 82.0 0.0 4e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 AEO57067.1 - 5.2e-17 61.7 0.0 9.6e-17 60.8 0.0 1.5 1 1 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 AEO57067.1 - 0.00048 20.0 0.0 0.0011 18.9 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme Zip PF02535.17 AEO57067.1 - 5 6.0 6.0 7.9 5.3 4.1 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter PHO4 PF01384.15 AEO57068.1 - 0.014 14.0 0.0 0.014 14.0 0.0 1.0 1 0 0 1 1 1 0 Phosphate transporter family ATP-synt_J PF04911.7 AEO57068.1 - 0.11 11.9 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 ATP synthase j chain DUF4192 PF13830.1 AEO57068.1 - 0.11 12.1 1.1 0.11 12.0 0.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) Mito_carr PF00153.22 AEO57069.1 - 2.1e-71 235.6 0.1 3.6e-25 87.5 0.1 3.3 2 1 1 3 3 3 3 Mitochondrial carrier protein UCR_14kD PF02271.11 AEO57070.1 - 1.7e-44 149.8 0.4 1.9e-44 149.7 0.3 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit MIR PF02815.14 AEO57070.1 - 0.037 13.5 0.0 0.041 13.4 0.0 1.1 1 0 0 1 1 1 0 MIR domain Anp1 PF03452.9 AEO57071.1 - 1.2e-112 375.5 0.0 1.4e-112 375.2 0.0 1.0 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 AEO57071.1 - 0.00096 18.8 0.4 0.009 15.7 0.2 2.2 2 1 0 2 2 2 1 Glycosyl transferase family 2 HhH-GPD PF00730.20 AEO57072.1 - 1.8e-15 57.1 0.0 4.2e-15 55.9 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF3439 PF11921.3 AEO57072.1 - 0.32 10.7 5.6 0.62 9.8 3.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Ecm33 PF12454.3 AEO57073.1 - 6.9e-14 51.4 0.2 2e-13 49.9 0.2 1.8 1 0 0 1 1 1 1 GPI-anchored cell wall organization protein Recep_L_domain PF01030.19 AEO57073.1 - 9e-11 41.7 0.4 0.00054 19.9 0.0 4.1 2 1 2 4 4 4 4 Receptor L domain HTH_29 PF13551.1 AEO57074.1 - 8.6e-06 25.8 0.2 1.2e-05 25.4 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 AEO57074.1 - 0.00011 21.7 0.0 0.00016 21.1 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_4 PF13613.1 AEO57074.1 - 0.0022 17.4 0.2 0.005 16.3 0.1 1.6 2 0 0 2 2 2 1 Helix-turn-helix of DDE superfamily endonuclease HTH_28 PF13518.1 AEO57074.1 - 0.0052 16.7 0.1 0.0078 16.1 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain GntR PF00392.16 AEO57074.1 - 0.0055 16.1 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_38 PF13936.1 AEO57074.1 - 0.0062 16.0 0.0 0.015 14.8 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_1 PF01527.15 AEO57074.1 - 0.027 14.4 0.1 0.033 14.1 0.1 1.2 1 0 0 1 1 1 0 Transposase HA2 PF04408.18 AEO57075.1 - 2.2e-23 82.1 0.0 2.2e-23 82.1 0.0 2.4 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 AEO57075.1 - 1.7e-22 79.3 0.0 3.8e-22 78.2 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 AEO57075.1 - 1.2e-12 47.4 0.0 3e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 AEO57075.1 - 1.6e-05 24.4 0.0 3.3e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 AEO57075.1 - 0.00016 21.8 0.0 0.00038 20.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 AEO57075.1 - 0.0027 16.6 0.0 0.0055 15.6 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.17 AEO57075.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain cobW PF02492.14 AEO57075.1 - 0.027 13.9 1.0 0.87 8.9 0.0 2.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 AEO57075.1 - 0.057 13.1 0.0 1 9.1 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain AAA_11 PF13086.1 AEO57075.1 - 0.83 9.1 0.0 0.83 9.1 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.1 AEO57075.1 - 3.6 7.8 0.0 3.6 7.8 0.0 2.8 2 1 0 2 2 1 0 AAA domain AMP-binding PF00501.23 AEO57076.1 - 2.9e-86 289.4 0.0 3.4e-86 289.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 AEO57076.1 - 5.3e-15 56.1 0.0 1.4e-14 54.7 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.8 AEO57076.1 - 0.0011 17.6 0.0 0.011 14.2 0.0 2.0 2 0 0 2 2 2 1 GH3 auxin-responsive promoter Motile_Sperm PF00635.21 AEO57077.1 - 7.4e-23 80.2 0.0 1.7e-22 79.0 0.0 1.6 1 0 0 1 1 1 1 MSP (Major sperm protein) domain CDC27 PF09507.5 AEO57077.1 - 0.031 13.5 7.6 0.04 13.1 5.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF812 PF05667.6 AEO57077.1 - 0.045 12.2 2.0 0.045 12.2 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF2077 PF09850.4 AEO57077.1 - 0.059 12.7 0.1 0.11 11.8 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2077) MRP-S31 PF15433.1 AEO57077.1 - 0.52 9.6 2.7 0.74 9.1 1.9 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 UBA PF00627.26 AEO57078.1 - 0.00016 21.3 0.2 0.0004 20.1 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain UBX PF00789.15 AEO57078.1 - 0.0018 18.3 0.2 0.0055 16.7 0.0 1.9 2 0 0 2 2 2 1 UBX domain zf-C2H2 PF00096.21 AEO57078.1 - 0.066 13.5 0.4 0.12 12.7 0.3 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type Ima1_N PF09779.4 AEO57078.1 - 0.079 13.4 0.6 0.27 11.7 0.0 2.0 1 1 1 2 2 2 0 Ima1 N-terminal domain SOBP PF15279.1 AEO57078.1 - 0.14 12.4 2.9 0.17 12.2 2.0 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein CAF-1_p150 PF11600.3 AEO57078.1 - 0.24 10.7 32.6 0.41 10.0 22.6 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF572 PF04502.8 AEO57078.1 - 0.4 9.8 22.6 0.58 9.3 15.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Asp-B-Hydro_N PF05279.6 AEO57078.1 - 0.49 10.1 15.6 0.71 9.6 10.8 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region LMBR1 PF04791.11 AEO57078.1 - 2 6.8 6.1 2.7 6.4 4.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein RR_TM4-6 PF06459.7 AEO57078.1 - 7.7 6.3 16.8 11 5.7 11.6 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 YCII PF03795.9 AEO57079.1 - 2.9e-11 43.3 0.0 3.4e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain DUF2408 PF10303.4 AEO57080.1 - 2e-47 160.6 7.9 1.9e-29 102.5 0.3 4.9 2 2 1 4 4 4 4 Protein of unknown function (DUF2408) DUF1539 PF07560.6 AEO57080.1 - 0.024 14.5 0.1 0.071 12.9 0.1 1.8 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) Cob_adeno_trans PF01923.13 AEO57080.1 - 0.11 12.2 3.0 2.2 8.0 0.0 3.5 2 1 1 4 4 4 0 Cobalamin adenosyltransferase NPV_P10 PF05531.7 AEO57080.1 - 2.9 8.2 11.0 16 5.7 0.8 4.7 5 1 0 5 5 5 0 Nucleopolyhedrovirus P10 protein Ribosomal_60s PF00428.14 AEO57081.1 - 1.3e-26 92.7 13.0 1.6e-26 92.4 9.0 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3824 PF12868.2 AEO57082.1 - 0.004 18.0 9.2 0.004 18.0 6.4 15.1 3 3 12 15 15 15 1 Domain of unknwon function (DUF3824) DUF4366 PF14283.1 AEO57082.1 - 0.07 12.5 22.1 0.19 11.1 1.2 4.2 3 1 1 4 4 4 0 Domain of unknown function (DUF4366) DnaJ PF00226.26 AEO57083.1 - 3.7e-27 93.8 2.7 6.6e-27 93.0 1.9 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 AEO57083.1 - 8.7e-15 54.5 16.6 1.5e-14 53.7 11.5 1.4 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 AEO57083.1 - 6e-14 51.7 0.0 1e-11 44.5 0.0 2.6 2 0 0 2 2 2 1 DnaJ C terminal domain HypA PF01155.14 AEO57083.1 - 0.48 10.1 8.9 2.1 8.0 0.9 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Antiterm PF03589.8 AEO57083.1 - 2.7 8.1 6.1 1.9 8.5 1.0 2.8 1 1 1 2 2 2 0 Antitermination protein DZR PF12773.2 AEO57083.1 - 5.3 6.9 11.7 21 5.0 1.4 2.2 1 1 1 2 2 2 0 Double zinc ribbon Methyltransf_23 PF13489.1 AEO57084.1 - 9.1e-16 57.9 0.0 1.3e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO57084.1 - 2.4e-06 27.9 0.0 5.7e-06 26.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO57084.1 - 4.4e-05 23.4 0.0 0.0001 22.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO57084.1 - 0.00019 21.8 0.0 0.00029 21.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO57084.1 - 0.0033 17.9 0.0 0.0091 16.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AEO57084.1 - 0.019 14.1 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 AEO57084.1 - 0.026 14.1 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 AEO57084.1 - 0.14 12.5 0.0 0.31 11.4 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain zf-CCHC PF00098.18 AEO57085.1 - 4.3e-12 45.3 7.9 4.1e-06 26.4 0.7 2.2 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 AEO57085.1 - 8.4e-05 22.1 5.0 0.013 15.1 0.0 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.1 AEO57085.1 - 0.0062 16.1 6.0 0.022 14.4 0.2 2.3 2 0 0 2 2 2 1 Zinc knuckle zf-ribbon_3 PF13248.1 AEO57085.1 - 0.017 14.2 3.7 0.45 9.8 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain NMT_C PF02799.10 AEO57085.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.4 1 1 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain zinc_ribbon_2 PF13240.1 AEO57085.1 - 0.8 9.2 4.6 9.2 5.9 0.3 2.5 2 0 0 2 2 2 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 AEO57085.1 - 1.2 8.4 5.9 17 4.8 4.1 2.4 1 1 0 1 1 1 0 TFIIB zinc-binding zf-CCHC PF00098.18 AEO57086.1 - 0.032 14.1 0.9 0.047 13.6 0.6 1.3 1 0 0 1 1 1 0 Zinc knuckle Aldo_ket_red PF00248.16 AEO57087.1 - 1e-70 237.7 0.0 1.2e-70 237.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FA_desaturase PF00487.19 AEO57088.1 - 3.1e-30 105.4 17.7 4e-30 105.1 12.3 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 AEO57088.1 - 1.8e-20 71.8 0.2 3.1e-20 71.1 0.1 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Vac7 PF12751.2 AEO57089.1 - 6.7e-110 367.5 24.6 9.3e-101 337.4 2.7 2.6 3 0 0 3 3 3 2 Vacuolar segregation subunit 7 Z1 PF10593.4 AEO57091.1 - 0.048 12.8 2.6 0.1 11.7 1.8 1.5 1 0 0 1 1 1 0 Z1 domain Herpes_UL6 PF01763.11 AEO57091.1 - 0.33 9.0 5.5 0.67 8.0 3.8 1.4 1 0 0 1 1 1 0 Herpesvirus UL6 like Ribosomal_L7Ae PF01248.21 AEO57092.1 - 3e-24 84.3 0.0 3.3e-24 84.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family HTH_IclR PF09339.5 AEO57092.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain Ribosomal_L16 PF00252.13 AEO57093.1 - 2.5e-31 108.1 0.0 3.3e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e NPV_P10 PF05531.7 AEO57095.1 - 0.013 15.6 1.2 0.48 10.7 0.0 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2968 PF11180.3 AEO57095.1 - 0.029 13.7 1.8 0.038 13.3 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) RrnaAD PF00398.15 AEO57096.1 - 2.5e-51 174.2 0.0 3.5e-51 173.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 AEO57096.1 - 2.6e-09 37.1 0.0 5.2e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO57096.1 - 4.6e-05 23.9 0.0 9.3e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 AEO57096.1 - 0.00017 21.2 0.0 0.00029 20.4 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.9 AEO57096.1 - 0.003 16.9 0.0 0.0064 15.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 AEO57096.1 - 0.0047 16.5 0.0 0.0095 15.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 AEO57096.1 - 0.005 15.9 0.0 0.0079 15.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Sigma70_ner PF04546.8 AEO57096.1 - 0.012 15.2 3.9 0.019 14.5 2.7 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region PCMT PF01135.14 AEO57096.1 - 0.034 13.6 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.1 AEO57096.1 - 0.035 13.8 0.0 0.06 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.13 AEO57096.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 CDC45 PF02724.9 AEO57096.1 - 0.13 10.2 1.2 0.17 9.8 0.8 1.1 1 0 0 1 1 1 0 CDC45-like protein BNIP2 PF12496.3 AEO57096.1 - 0.32 11.1 7.9 1.6 8.8 6.0 1.7 1 1 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 CENP-T PF15511.1 AEO57096.1 - 0.43 9.7 4.8 0.63 9.2 3.3 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T SDA1 PF05285.7 AEO57096.1 - 1.6 7.9 9.7 2.4 7.3 6.7 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 AEO57096.1 - 4.9 4.9 11.8 6.4 4.5 8.2 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 AEO57096.1 - 5.2 5.4 7.4 6.8 5.0 5.2 1.1 1 0 0 1 1 1 0 Daxx Family Arrestin_N PF00339.24 AEO57097.1 - 6.5e-14 51.9 0.0 6.8e-07 29.2 0.0 2.6 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Dicty_REP PF05086.7 AEO57097.1 - 0.024 12.4 1.2 0.032 11.9 0.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Med3 PF11593.3 AEO57097.1 - 0.38 9.9 5.0 0.53 9.4 3.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TFIIA PF03153.8 AEO57097.1 - 3.6 7.4 4.7 5.3 6.8 3.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3439 PF11921.3 AEO57097.1 - 9.3 6.0 13.9 18 5.0 9.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) zf-MIZ PF02891.15 AEO57098.1 - 1.3e-07 31.0 7.8 6.3e-06 25.6 0.1 2.5 1 1 1 2 2 2 2 MIZ/SP-RING zinc finger UTP15_C PF09384.5 AEO57099.1 - 9e-47 158.4 0.0 1.4e-46 157.9 0.0 1.2 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 AEO57099.1 - 1.5e-26 91.2 1.8 4.6e-08 32.6 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat PQQ_3 PF13570.1 AEO57099.1 - 0.034 14.4 1.9 1e+02 3.3 0.0 4.5 4 0 0 4 4 4 0 PQQ-like domain Pkinase PF00069.20 AEO57100.1 - 3.5e-72 242.6 0.0 4.2e-72 242.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO57100.1 - 3.4e-31 108.2 0.0 4.8e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AEO57100.1 - 0.016 14.9 0.1 0.065 12.9 0.1 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 AEO57100.1 - 0.078 12.0 0.0 0.21 10.6 0.0 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LMWPc PF01451.16 AEO57101.1 - 3e-35 121.5 0.0 3.3e-35 121.3 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase SIS PF01380.17 AEO57102.1 - 1.5e-11 44.0 0.0 4.4e-11 42.5 0.0 1.7 2 0 0 2 2 2 1 SIS domain SIS_2 PF13580.1 AEO57102.1 - 0.0002 21.0 0.0 0.0023 17.6 0.1 2.1 1 1 1 2 2 2 1 SIS domain DUF3619 PF12279.3 AEO57102.1 - 0.091 12.8 0.0 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) DUF2373 PF10180.4 AEO57103.1 - 1.2e-22 79.2 4.0 2.1e-22 78.4 0.2 2.5 3 0 0 3 3 3 1 Uncharacterised conserved protein (DUF2373) Proteasome PF00227.21 AEO57104.1 - 6.2e-49 165.8 0.0 8.4e-49 165.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 AEO57104.1 - 3.8e-13 48.4 0.2 3.8e-13 48.4 0.2 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF550 PF04447.7 AEO57104.1 - 0.069 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF550) DUF3650 PF12368.3 AEO57104.1 - 0.089 12.2 0.5 0.089 12.2 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3650) DUF2011 PF09428.5 AEO57105.1 - 0.022 14.6 0.0 0.038 13.8 0.0 1.5 1 1 0 1 1 1 0 Fungal protein of unknown function (DUF2011) DUF1311 PF07007.7 AEO57105.1 - 1.8 8.7 6.0 1.3 9.2 2.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1311) UPF0546 PF10639.4 AEO57106.1 - 3.4e-36 123.5 0.1 7.4e-36 122.4 0.1 1.5 1 1 0 1 1 1 1 Uncharacterised protein family UPF0546 EamA PF00892.15 AEO57106.1 - 0.0026 17.7 4.3 0.024 14.6 3.1 2.1 2 0 0 2 2 2 1 EamA-like transporter family DUF1211 PF06736.6 AEO57106.1 - 0.037 14.1 0.0 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1211) PetM PF08041.6 AEO57106.1 - 0.13 11.7 1.2 0.43 10.0 0.9 1.9 1 0 0 1 1 1 0 PetM family of cytochrome b6f complex subunit 7 C2 PF00168.25 AEO57107.1 - 5.7e-13 48.5 0.0 9.1e-13 47.8 0.0 1.3 1 0 0 1 1 1 1 C2 domain DUF3668 PF12416.3 AEO57107.1 - 0.016 14.3 0.0 0.026 13.7 0.0 1.2 1 0 0 1 1 1 0 Cep120 protein DUF3455 PF11937.3 AEO57108.1 - 1.7e-27 96.4 0.0 2.5e-27 95.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) HET PF06985.6 AEO57109.1 - 3.1e-09 37.1 0.0 3.4e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-NADH-PPase PF09297.6 AEO57112.1 - 0.081 12.4 4.8 0.17 11.3 3.3 1.6 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_5 PF13719.1 AEO57112.1 - 0.13 11.8 3.8 0.37 10.4 0.3 2.4 2 0 0 2 2 2 0 zinc-ribbon domain C1_1 PF00130.17 AEO57112.1 - 0.26 11.0 6.1 0.62 9.8 4.2 1.7 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_4 PF13717.1 AEO57112.1 - 0.42 10.3 4.5 0.78 9.4 0.4 2.4 2 0 0 2 2 2 0 zinc-ribbon domain 4HBT_2 PF13279.1 AEO57114.1 - 0.00021 21.7 0.0 0.00039 20.8 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily APH PF01636.18 AEO57118.1 - 2.8e-20 73.0 0.0 5.9e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 AEO57118.1 - 3.1e-06 26.9 0.0 5.5e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 AEO57118.1 - 0.036 13.2 0.0 0.51 9.4 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain DUF1679 PF07914.6 AEO57118.1 - 0.19 10.3 0.0 0.4 9.2 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) ATP-grasp_4 PF13535.1 AEO57121.1 - 5.1e-21 75.2 0.0 4.7e-19 68.8 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 AEO57121.1 - 1.6e-05 24.4 0.0 2.7e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 AEO57121.1 - 0.00014 20.7 0.0 0.046 12.4 0.0 2.6 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon NAS PF03059.11 AEO57122.1 - 5.1e-63 212.8 0.0 3.9e-36 124.6 0.0 2.1 2 0 0 2 2 2 2 Nicotianamine synthase protein 2OG-FeII_Oxy_2 PF13532.1 AEO57123.1 - 1.7e-17 63.9 0.5 3.3e-17 62.9 0.3 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 AEO57123.1 - 9.4e-10 38.6 0.1 3.4e-07 30.4 0.0 2.7 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 AEO57123.1 - 0.098 13.1 0.2 0.32 11.5 0.0 2.0 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily SR-25 PF10500.4 AEO57124.1 - 0.00054 19.4 8.3 0.00062 19.3 5.7 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein HMG_box_2 PF09011.5 AEO57124.1 - 0.0082 16.4 0.1 0.0082 16.4 0.1 2.1 2 1 0 2 2 2 1 HMG-box domain DUF3446 PF11928.3 AEO57124.1 - 0.021 15.0 4.9 0.032 14.4 3.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) DUF755 PF05501.6 AEO57124.1 - 0.076 13.0 10.3 0.1 12.6 7.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF1117 PF06547.7 AEO57124.1 - 0.18 11.9 2.1 0.24 11.4 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1117) NAD_binding_10 PF13460.1 AEO57125.1 - 1.7e-07 31.3 1.8 6.3e-07 29.5 1.2 1.9 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 AEO57125.1 - 8.5e-07 28.6 0.0 1.1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 AEO57125.1 - 0.00048 18.9 0.0 0.00069 18.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 AEO57125.1 - 0.0012 18.1 0.1 0.0027 17.0 0.1 1.6 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.20 AEO57125.1 - 0.029 14.2 2.3 0.068 13.0 1.6 1.7 1 1 0 1 1 1 0 short chain dehydrogenase Hexapep PF00132.19 AEO57126.1 - 1.8e-10 39.7 9.5 5.1e-06 25.7 0.6 4.2 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 AEO57126.1 - 4.4e-05 22.9 3.0 0.06 12.9 0.1 3.3 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 AEO57126.1 - 0.16 10.5 0.0 0.22 10.0 0.0 1.2 1 0 0 1 1 1 0 L-fucokinase Rhodanese PF00581.15 AEO57127.1 - 1.7e-10 41.2 0.0 2.5e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Dioxygenase_C PF00775.16 AEO57128.1 - 2.6e-09 36.5 0.1 4.2e-09 35.9 0.1 1.3 1 0 0 1 1 1 1 Dioxygenase DUF3005 PF11448.3 AEO57128.1 - 0.13 11.9 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3005) polyprenyl_synt PF00348.12 AEO57129.1 - 1.5e-11 43.6 0.0 1.7e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Peptidase_M43 PF05572.8 AEO57130.1 - 7.1e-18 64.6 0.4 1.1e-17 64.1 0.3 1.2 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 AEO57130.1 - 6.8e-06 26.1 0.6 9e-06 25.7 0.4 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 AEO57130.1 - 1.3e-05 25.2 0.3 1.8e-05 24.8 0.2 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 AEO57130.1 - 6.9e-05 23.3 0.7 0.00012 22.5 0.5 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M7 PF02031.11 AEO57130.1 - 0.0048 16.6 0.6 0.0089 15.7 0.4 1.5 1 0 0 1 1 1 1 Streptomyces extracellular neutral proteinase (M7) family Peptidase_M10 PF00413.19 AEO57130.1 - 0.0095 15.6 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Matrixin Reprolysin_4 PF13583.1 AEO57130.1 - 0.0098 15.4 1.1 0.016 14.7 0.8 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Rib_hydrolayse PF02267.12 AEO57130.1 - 0.023 14.0 0.1 0.29 10.4 0.0 2.1 2 0 0 2 2 2 0 ADP-ribosyl cyclase Peptidase_M66 PF10462.4 AEO57130.1 - 0.081 11.7 1.0 0.13 11.1 0.7 1.2 1 0 0 1 1 1 0 Peptidase M66 Sugar_tr PF00083.19 AEO57131.1 - 4.6e-111 371.5 22.4 5.4e-111 371.3 15.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO57131.1 - 5.2e-25 87.9 28.2 8.6e-17 60.8 3.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 AEO57131.1 - 0.0012 16.9 0.5 0.0024 16.0 0.3 1.4 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Lambda_tail_I PF06805.7 AEO57131.1 - 0.015 15.0 0.0 0.036 13.9 0.0 1.7 1 0 0 1 1 1 0 Bacteriophage lambda tail assembly protein I Abhydrolase_2 PF02230.11 AEO57132.1 - 1.4e-05 24.6 0.0 2.3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase PF00756.15 AEO57132.1 - 0.008 15.6 0.4 0.055 12.8 0.3 2.2 1 1 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.2 AEO57132.1 - 0.017 14.9 1.9 0.029 14.2 1.3 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO57132.1 - 0.084 12.6 0.4 0.15 11.7 0.3 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Esterase_phd PF10503.4 AEO57132.1 - 0.09 12.0 1.9 0.085 12.0 0.3 1.8 2 0 0 2 2 2 0 Esterase PHB depolymerase Tub_2 PF04525.7 AEO57133.1 - 6.2e-18 64.8 0.0 7.8e-18 64.5 0.0 1.1 1 0 0 1 1 1 1 Tubby C 2 Amidoligase_2 PF12224.3 AEO57135.1 - 1.6e-22 80.3 0.7 3.2e-22 79.3 0.5 1.5 1 1 0 1 1 1 1 Putative amidoligase enzyme Sugar_tr PF00083.19 AEO57136.1 - 4.8e-75 252.8 23.0 5.5e-75 252.6 15.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO57136.1 - 8e-19 67.5 29.9 5.4e-16 58.2 12.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily F-box-like PF12937.2 AEO57137.1 - 3.5e-05 23.4 0.5 3.5e-05 23.4 0.4 2.3 2 0 0 2 2 2 1 F-box-like EamA PF00892.15 AEO57138.1 - 1.1e-11 44.8 29.1 4.1e-06 26.8 11.2 2.9 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 AEO57138.1 - 1.6e-06 28.3 1.2 1.6e-06 28.3 0.8 3.2 3 0 0 3 3 3 2 Multidrug resistance efflux transporter TPT PF03151.11 AEO57138.1 - 0.0006 19.4 11.4 0.0006 19.4 7.9 2.8 3 1 0 3 3 3 2 Triose-phosphate Transporter family DUF1218 PF06749.7 AEO57138.1 - 1.2 9.6 12.6 0.71 10.3 1.4 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1218) Ank PF00023.25 AEO57139.1 - 8.2e-16 56.9 0.8 3e-08 33.0 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 AEO57139.1 - 2e-12 47.2 0.3 9.7e-05 22.6 0.3 3.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 AEO57139.1 - 2.1e-11 44.0 2.1 0.00068 20.0 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 AEO57139.1 - 4e-10 39.6 1.6 2.6e-06 27.4 0.2 3.8 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 AEO57139.1 - 3.2e-07 29.9 0.6 0.14 12.4 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.8 AEO57139.1 - 7.6e-07 28.7 0.2 6.2e-06 25.7 0.2 2.3 1 1 0 1 1 1 1 KilA-N domain Aldo_ket_red PF00248.16 AEO57143.1 - 3e-53 180.4 0.0 3.4e-53 180.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PNP_UDP_1 PF01048.15 AEO57146.1 - 3.7e-14 52.2 0.0 9.6e-14 50.9 0.0 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily TPR_10 PF13374.1 AEO57146.1 - 2.8e-09 36.6 5.2 0.0057 16.5 0.1 4.9 6 0 0 6 6 5 2 Tetratricopeptide repeat NB-ARC PF00931.17 AEO57146.1 - 2.3e-07 29.9 0.0 4.2e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_12 PF13424.1 AEO57146.1 - 3e-07 30.2 0.2 0.012 15.5 0.0 4.1 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 AEO57146.1 - 1.7e-06 28.2 0.2 5 7.5 0.0 5.3 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.9 AEO57146.1 - 1.8e-06 27.8 1.4 0.033 14.6 1.9 4.8 5 0 0 5 5 4 1 Tetratricopeptide repeat AAA_22 PF13401.1 AEO57146.1 - 9.5e-05 22.5 0.0 0.00026 21.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 AEO57146.1 - 0.0003 20.2 0.0 0.0012 18.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain TPR_2 PF07719.12 AEO57146.1 - 0.00054 19.6 6.2 0.96 9.5 0.0 4.8 6 0 0 6 6 4 2 Tetratricopeptide repeat Apc3 PF12895.2 AEO57146.1 - 0.0015 18.5 0.0 4.8 7.3 0.0 4.2 4 1 1 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 AEO57146.1 - 0.0017 18.9 3.5 1.2 9.8 0.2 4.6 5 0 0 5 5 4 1 Tetratricopeptide repeat AAA_16 PF13191.1 AEO57146.1 - 0.0075 16.2 0.0 0.036 14.0 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain TPR_14 PF13428.1 AEO57146.1 - 0.0076 16.7 5.3 62 4.6 0.0 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat PPR PF01535.15 AEO57146.1 - 0.023 14.6 0.5 1.2 9.2 0.0 3.7 5 0 0 5 5 3 0 PPR repeat TPR_1 PF00515.23 AEO57146.1 - 0.091 12.4 0.9 4.5 7.0 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 AEO57146.1 - 0.11 12.1 0.3 6.9 6.4 0.0 2.9 2 0 0 2 2 2 0 TPR repeat TPR_8 PF13181.1 AEO57146.1 - 0.19 11.5 1.1 0.7 9.8 0.1 2.4 3 0 0 3 3 2 0 Tetratricopeptide repeat MFS_1 PF07690.11 AEO57147.1 - 2.9e-22 78.8 29.9 2.9e-22 78.8 20.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily NDUF_B7 PF05676.8 AEO57148.1 - 1e-31 108.0 4.9 1.2e-31 107.8 3.4 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 AEO57148.1 - 0.011 15.5 3.1 0.012 15.3 1.8 1.4 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like dCMP_cyt_deam_1 PF00383.17 AEO57150.1 - 1.8e-06 27.5 0.0 3.4e-06 26.6 0.0 1.4 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MOSC PF03473.12 AEO57150.1 - 0.1 12.0 0.1 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 MOSC domain CTF_NFI PF00859.13 AEO57151.1 - 0.0052 16.5 1.1 0.0052 16.5 0.7 1.6 2 0 0 2 2 2 1 CTF/NF-I family transcription modulation region DUF4407 PF14362.1 AEO57151.1 - 0.032 13.1 1.9 0.043 12.7 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UPF0560 PF10577.4 AEO57151.1 - 5.2 5.2 6.9 8.3 4.5 4.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 CDC45 PF02724.9 AEO57151.1 - 6.1 4.7 14.4 7.9 4.3 10.0 1.1 1 0 0 1 1 1 0 CDC45-like protein HSP20 PF00011.16 AEO57153.1 - 1.6e-18 66.4 0.1 2.5e-12 46.5 0.0 2.1 1 1 1 2 2 2 2 Hsp20/alpha crystallin family Response_reg PF00072.19 AEO57154.1 - 2.3e-25 88.7 0.2 4.9e-25 87.7 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 AEO57154.1 - 3.6e-25 87.8 0.0 1.1e-24 86.3 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.1 AEO57154.1 - 7.5e-19 68.0 0.0 2e-14 53.8 0.0 2.5 2 0 0 2 2 2 2 PAS domain HisKA PF00512.20 AEO57154.1 - 1e-18 67.0 0.1 2.3e-18 65.9 0.1 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS PF00989.19 AEO57154.1 - 4.6e-11 42.4 0.0 1.1e-08 34.8 0.0 2.6 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.5 AEO57154.1 - 5.3e-09 36.0 0.0 2.9e-05 24.0 0.0 2.6 2 0 0 2 2 2 2 PAS fold ASFV_J13L PF05568.6 AEO57154.1 - 0.068 12.6 14.3 0.2 11.1 9.9 1.7 1 0 0 1 1 1 0 African swine fever virus J13L protein Gemin7 PF11095.3 AEO57154.1 - 0.076 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) SSP160 PF06933.6 AEO57154.1 - 8.1 4.2 17.4 12 3.6 12.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 UCR_Fe-S_N PF10399.4 AEO57155.1 - 3.2 6.9 5.6 6.3 6.0 3.9 1.4 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal FAD_binding_3 PF01494.14 AEO57156.1 - 8.7e-17 61.1 1.1 2.2e-05 23.6 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain FAD_binding_2 PF00890.19 AEO57156.1 - 1.4e-09 37.3 1.2 1.1e-08 34.3 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 AEO57156.1 - 1.7e-09 37.0 1.3 3.3e-06 26.2 0.0 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.2 AEO57156.1 - 1e-07 31.4 0.0 1.6e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 AEO57156.1 - 1.1e-06 28.7 0.2 5.2e-06 26.4 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AEO57156.1 - 1.2e-06 28.4 0.1 2.9e-06 27.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 AEO57156.1 - 1.2e-06 27.2 0.3 4.1e-06 25.5 0.3 1.7 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 AEO57156.1 - 3.3e-06 26.2 0.0 4.7e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 AEO57156.1 - 8.5e-05 22.8 0.0 0.0034 17.7 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 AEO57156.1 - 0.00014 20.6 0.1 0.18 10.3 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox_3 PF13738.1 AEO57156.1 - 0.00031 20.8 0.1 0.00058 19.9 0.1 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 AEO57156.1 - 0.0075 15.2 0.3 0.03 13.2 0.2 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.9 AEO57156.1 - 0.018 14.4 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Thi4 PF01946.12 AEO57156.1 - 0.029 13.4 0.5 0.05 12.6 0.1 1.5 2 0 0 2 2 2 0 Thi4 family AlaDh_PNT_C PF01262.16 AEO57156.1 - 0.055 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 AEO57156.1 - 0.06 12.9 0.2 0.094 12.3 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 AEO57156.1 - 0.17 11.5 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Glyco_hydro_11 PF00457.12 AEO57157.1 - 1.5e-78 262.3 15.1 1.9e-78 262.0 10.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 CBM_1 PF00734.13 AEO57157.1 - 1.2e-09 37.7 16.1 1.2e-09 37.7 11.2 2.5 2 0 0 2 2 2 1 Fungal cellulose binding domain Toxin_7 PF05980.7 AEO57157.1 - 0.0066 16.4 6.2 0.014 15.4 4.2 1.6 1 1 0 1 1 1 1 Toxin 7 GRP PF07172.6 AEO57157.1 - 0.75 10.3 21.3 10 6.6 11.1 2.4 2 0 0 2 2 2 0 Glycine rich protein family RVT_1 PF00078.22 AEO57158.1 - 5.5e-06 25.8 0.5 6.3e-06 25.7 0.3 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Acetyltransf_1 PF00583.19 AEO57160.1 - 0.00051 20.0 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 AEO57160.1 - 0.006 16.4 0.0 0.0087 15.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 AEO57160.1 - 0.035 14.2 0.0 0.066 13.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 AEO57160.1 - 0.062 13.4 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pkinase PF00069.20 AEO57161.1 - 6.8e-18 64.7 0.0 2e-17 63.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO57161.1 - 2e-14 53.3 0.0 3.1e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 AEO57161.1 - 0.0003 19.9 0.0 0.00047 19.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AEO57161.1 - 0.004 16.9 0.2 0.0084 15.8 0.2 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 AEO57161.1 - 0.0062 15.8 0.0 0.0088 15.4 0.0 1.2 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL DUF946 PF06101.6 AEO57162.1 - 1.3e-10 39.9 0.2 2e-10 39.3 0.1 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF946) DUF1302 PF06980.6 AEO57162.1 - 0.023 13.3 0.1 0.023 13.3 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1302) TFIIIC_sub6 PF10419.4 AEO57163.1 - 3.6e-13 48.7 0.0 5.7e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 TFIIIC subunit DUF1675 PF07897.6 AEO57163.1 - 0.19 11.5 1.9 0.28 11.0 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) His_biosynth PF00977.16 AEO57164.1 - 2.1e-49 167.8 0.8 8.3e-49 165.9 0.5 2.0 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 AEO57164.1 - 8e-26 90.6 0.0 1.3e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.14 AEO57164.1 - 8.4e-09 35.3 0.0 1.3e-06 28.1 0.0 2.3 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 AEO57164.1 - 2.7e-07 30.3 0.0 9e-07 28.6 0.0 1.9 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Dus PF01207.12 AEO57164.1 - 0.011 14.5 0.1 0.026 13.3 0.0 1.6 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) Peptidase_C26 PF07722.8 AEO57164.1 - 0.052 12.9 0.0 0.71 9.2 0.0 2.1 2 0 0 2 2 2 0 Peptidase C26 CABIT PF12736.2 AEO57164.1 - 0.085 11.8 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Cell-cycle sustaining, positive selection, ODC_AZ PF02100.12 AEO57165.1 - 1.9e-27 94.8 0.0 2.6e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Yippee-Mis18 PF03226.9 AEO57166.1 - 1.6e-16 60.1 0.0 4.8e-16 58.5 0.0 1.7 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-dskA_traR PF01258.12 AEO57166.1 - 0.0078 15.9 1.3 1.8 8.3 0.2 3.1 3 0 0 3 3 3 2 Prokaryotic dksA/traR C4-type zinc finger Peptidase_M20 PF01546.23 AEO57167.1 - 2.1e-33 115.4 0.0 3.8e-33 114.5 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 AEO57167.1 - 6.5e-14 51.6 0.0 1.1e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Shugoshin_N PF07558.6 AEO57168.1 - 0.011 15.4 1.9 0.023 14.3 1.3 1.6 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region TPR_MLP1_2 PF07926.7 AEO57168.1 - 0.025 14.3 0.8 0.051 13.3 0.6 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Peptidase_S8 PF00082.17 AEO57169.1 - 1.8e-49 168.4 17.4 2.5e-49 167.9 12.0 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 AEO57169.1 - 1.1e-08 35.4 0.0 3.8e-08 33.7 0.0 2.0 1 1 0 1 1 1 1 Peptidase inhibitor I9 YfbU PF03887.9 AEO57169.1 - 0.062 12.8 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 YfbU domain Pkinase_Tyr PF07714.12 AEO57170.1 - 4.2e-16 58.8 0.0 5.7e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 AEO57170.1 - 1.5e-14 53.7 0.0 4.3e-14 52.2 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.1 AEO57170.1 - 0.00026 20.0 0.0 0.0004 19.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AEO57170.1 - 0.085 12.5 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family TFIID-18kDa PF02269.11 AEO57172.1 - 8.5e-20 70.3 1.1 3e-19 68.6 0.2 2.1 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit ERF PF04404.7 AEO57172.1 - 0.19 11.2 2.7 0.46 9.9 0.9 2.0 2 0 0 2 2 2 0 ERF superfamily DUF4611 PF15387.1 AEO57172.1 - 3.8 7.7 6.2 2.4 8.3 0.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Pox_Rif PF03340.8 AEO57173.1 - 0.01 13.9 0.4 0.013 13.6 0.3 1.1 1 0 0 1 1 1 0 Poxvirus rifampicin resistance protein AIF_C PF14721.1 AEO57173.1 - 0.3 11.3 1.6 0.43 10.8 1.1 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term PMI_typeI PF01238.16 AEO57174.1 - 1.4e-137 458.6 0.0 1.6e-137 458.4 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.14 AEO57174.1 - 0.0064 16.1 0.0 3.6 7.2 0.0 2.8 3 0 0 3 3 3 2 AraC-like ligand binding domain DUF1325 PF07039.6 AEO57175.1 - 7.7e-26 90.2 0.0 1.2e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain Arf PF00025.16 AEO57176.1 - 1.3e-73 245.9 0.0 1.5e-73 245.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 AEO57176.1 - 8.8e-15 54.3 0.0 1.1e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 AEO57176.1 - 2.1e-12 46.4 1.4 1.9e-08 33.4 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 AEO57176.1 - 6.3e-12 45.1 0.0 6.5e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 AEO57176.1 - 1.4e-09 37.4 0.0 1.8e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 AEO57176.1 - 9.9e-06 26.0 0.0 1.6e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 AEO57176.1 - 0.00027 20.8 0.0 0.00054 19.9 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 AEO57176.1 - 0.005 15.9 0.0 0.0055 15.7 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase Pkinase PF00069.20 AEO57177.1 - 1.7e-63 214.2 0.0 2.2e-63 213.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO57177.1 - 1.1e-31 109.8 0.0 1.7e-31 109.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO57177.1 - 0.0058 15.6 0.0 0.0094 14.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AEO57177.1 - 0.028 14.1 0.0 0.23 11.1 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Actin PF00022.14 AEO57178.1 - 5.8e-118 393.7 0.0 7.3e-118 393.4 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 AEO57178.1 - 0.042 12.4 0.0 0.31 9.5 0.0 2.1 1 1 0 1 1 1 0 MreB/Mbl protein Asp_Glu_race PF01177.17 AEO57179.1 - 5e-21 75.6 0.0 5.8e-21 75.4 0.0 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Sugar_tr PF00083.19 AEO57180.1 - 1.8e-82 277.3 19.1 6.1e-46 156.9 2.2 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 AEO57180.1 - 1.2e-31 109.7 34.3 3.8e-30 104.8 19.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily NmrA PF05368.8 AEO57180.1 - 4.7e-31 107.8 0.0 6.4e-31 107.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family TRI12 PF06609.8 AEO57180.1 - 2.2e-11 42.6 3.5 5e-11 41.5 2.4 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) NAD_binding_10 PF13460.1 AEO57180.1 - 1.6e-10 41.3 0.0 2.8e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 AEO57180.1 - 3.8e-06 25.8 0.0 5.8e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 AEO57180.1 - 6.1e-06 25.8 0.0 5.7e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 AEO57180.1 - 9.7e-05 22.6 0.0 0.00023 21.4 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 AEO57180.1 - 0.00027 20.6 0.0 0.00051 19.7 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 AEO57180.1 - 0.00029 20.7 0.0 0.00054 19.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 AEO57180.1 - 0.018 13.9 0.0 0.028 13.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TrkA_N PF02254.13 AEO57180.1 - 0.019 14.9 0.0 0.045 13.7 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Saccharop_dh PF03435.13 AEO57180.1 - 0.04 12.8 0.1 0.2 10.5 0.0 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase SHS2_Rpb7-N PF03876.12 AEO57181.1 - 5e-07 29.7 0.0 8.2e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 MIP-T3 PF10243.4 AEO57181.1 - 2.2e-05 23.1 39.0 3.3e-05 22.5 27.1 1.3 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Spore_YhcN_YlaJ PF09580.5 AEO57182.1 - 0.11 12.5 0.1 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Senescence_reg PF04520.8 AEO57183.1 - 0.029 14.8 0.9 0.039 14.4 0.6 1.2 1 0 0 1 1 1 0 Senescence regulator Pro_isomerase PF00160.16 AEO57184.1 - 1.5e-33 116.2 0.0 2.4e-33 115.5 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 AEO57184.1 - 5.3e-17 61.2 0.0 9.4e-17 60.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO57184.1 - 4.2e-11 42.6 0.0 9.4e-11 41.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO57184.1 - 1.6e-09 37.4 0.0 3.3e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zn_clus PF00172.13 AEO57185.1 - 3.3e-09 36.5 8.1 5e-09 35.9 5.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BAF1_ABF1 PF04684.8 AEO57185.1 - 3.3 6.4 11.6 4.5 5.9 8.0 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Methyltransf_16 PF10294.4 AEO57186.1 - 4.4e-19 68.5 0.0 6.6e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 AEO57186.1 - 3.2e-06 27.6 0.0 8.6e-06 26.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO57186.1 - 0.0006 19.8 0.1 0.0012 18.8 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AEO57186.1 - 0.00065 19.1 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.11 AEO57186.1 - 0.0024 17.4 0.0 0.004 16.7 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_23 PF13489.1 AEO57186.1 - 0.0026 17.5 0.0 0.0041 16.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 AEO57186.1 - 0.0034 16.9 0.0 0.0056 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.1 AEO57186.1 - 0.0044 17.3 0.0 0.0083 16.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.7 AEO57186.1 - 0.006 16.1 0.0 0.01 15.4 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF938) PrmA PF06325.8 AEO57186.1 - 0.0062 15.6 0.1 0.0089 15.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.7 AEO57186.1 - 0.0062 16.9 0.0 0.056 13.9 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO57186.1 - 0.0067 16.0 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO57186.1 - 0.072 13.5 0.0 0.21 12.1 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_32 PF13679.1 AEO57186.1 - 0.084 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_S24e PF01282.14 AEO57187.1 - 1.4e-37 127.3 0.0 2.2e-37 126.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e GTP_cyclohydro2 PF00925.15 AEO57189.1 - 2.3e-57 192.9 0.0 8.8e-52 174.7 0.0 2.1 2 0 0 2 2 2 2 GTP cyclohydrolase II DUF2172 PF09940.4 AEO57189.1 - 0.16 10.3 0.0 0.24 9.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2172) Glyco_hydro_6 PF01341.12 AEO57190.1 - 2.5e-92 309.4 0.2 2.9e-92 309.2 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Abhydrolase_6 PF12697.2 AEO57193.1 - 5.5e-11 42.7 6.1 8.2e-11 42.2 1.3 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO57193.1 - 1.3e-09 37.9 0.1 2.1e-09 37.2 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1100 PF06500.6 AEO57193.1 - 1.2e-06 27.3 0.1 4.1e-06 25.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S9 PF00326.16 AEO57193.1 - 0.054 12.7 0.1 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family G3P_acyltransf PF02660.10 AEO57194.1 - 0.0092 15.5 1.4 0.066 12.7 0.2 2.1 2 0 0 2 2 2 1 Glycerol-3-phosphate acyltransferase Nramp PF01566.13 AEO57194.1 - 0.11 11.2 0.1 0.11 11.2 0.1 1.8 2 1 0 3 3 3 0 Natural resistance-associated macrophage protein DUF3643 PF12356.3 AEO57194.1 - 0.28 10.5 2.3 9.3 5.5 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3643) MFS_1 PF07690.11 AEO57195.1 - 1.1e-41 142.7 52.4 3.9e-41 140.9 34.9 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 AEO57195.1 - 4.6e-17 61.4 13.9 5.6e-17 61.1 9.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 AEO57195.1 - 5.5e-13 48.3 9.5 5.5e-13 48.3 6.6 2.6 3 0 0 3 3 3 2 Sugar (and other) transporter SKG6 PF08693.5 AEO57195.1 - 0.036 13.3 0.0 0.036 13.3 0.0 3.2 4 0 0 4 4 4 0 Transmembrane alpha-helix domain CinA PF02464.12 AEO57196.1 - 0.011 15.2 0.2 0.03 13.7 0.0 1.7 2 0 0 2 2 2 0 Competence-damaged protein AMP-binding PF00501.23 AEO57197.1 - 1.2e-87 294.0 0.0 2.3e-87 293.0 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 AEO57197.1 - 9.9e-75 251.2 0.0 2.7e-74 249.8 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 AEO57197.1 - 3.6e-52 176.6 0.3 2.6e-50 170.6 0.0 2.9 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.16 AEO57197.1 - 8.6e-49 166.5 0.5 1.8e-48 165.5 0.0 1.7 2 0 0 2 2 2 1 Acyl transferase domain adh_short PF00106.20 AEO57197.1 - 4.9e-45 153.4 4.2 1.9e-41 141.7 0.0 3.7 4 0 0 4 4 2 2 short chain dehydrogenase PS-DH PF14765.1 AEO57197.1 - 1.1e-43 149.5 0.3 1.1e-43 149.5 0.2 2.1 2 0 0 2 2 2 1 Polyketide synthase dehydratase NAD_binding_4 PF07993.7 AEO57197.1 - 1.2e-36 125.9 0.0 2.1e-35 121.8 0.0 2.3 2 0 0 2 2 2 1 Male sterility protein Condensation PF00668.15 AEO57197.1 - 2.5e-36 125.1 0.2 3.4e-33 114.7 0.2 2.3 1 1 1 2 2 2 2 Condensation domain Ketoacyl-synt_C PF02801.17 AEO57197.1 - 4e-27 94.4 0.0 1.6e-26 92.5 0.0 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Epimerase PF01370.16 AEO57197.1 - 7.7e-21 74.6 0.0 2.5e-18 66.3 0.0 2.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 AEO57197.1 - 1.1e-16 60.8 0.8 1.9e-09 37.6 0.0 3.5 3 0 0 3 3 3 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 AEO57197.1 - 7.9e-15 55.1 0.0 1.8e-14 53.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO57197.1 - 4.7e-12 45.9 0.0 1.4e-11 44.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain HxxPF_rpt PF13745.1 AEO57197.1 - 1.3e-10 41.4 0.0 3.9e-10 39.9 0.0 1.9 1 0 0 1 1 1 1 HxxPF-repeated domain Methyltransf_11 PF08241.7 AEO57197.1 - 1.9e-10 41.0 0.0 5e-10 39.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO57197.1 - 1.2e-09 37.9 0.0 2.9e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain 3Beta_HSD PF01073.14 AEO57197.1 - 2.1e-08 33.2 0.0 1e-07 30.9 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_18 PF12847.2 AEO57197.1 - 1.6e-07 31.8 0.0 9.5e-07 29.3 0.0 2.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AEO57197.1 - 1.1e-05 24.7 0.0 2.1e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.18 AEO57197.1 - 9.3e-05 21.5 0.0 0.00018 20.6 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain RmlD_sub_bind PF04321.12 AEO57197.1 - 0.0061 15.4 0.1 0.26 10.1 0.1 3.2 2 1 0 2 2 2 1 RmlD substrate binding domain Semialdhyde_dh PF01118.19 AEO57197.1 - 0.009 16.3 0.0 0.061 13.6 0.0 2.5 2 0 0 2 2 1 1 Semialdehyde dehydrogenase, NAD binding domain Methyltransf_16 PF10294.4 AEO57197.1 - 0.038 13.4 0.0 0.081 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase RrnaAD PF00398.15 AEO57197.1 - 0.31 10.0 0.0 0.6 9.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Polysacc_synt_2 PF02719.10 AEO57197.1 - 0.57 9.0 0.0 4 6.2 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DUF915 PF06028.6 AEO57197.1 - 8.3 5.4 0.0 15 4.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) ADH_zinc_N PF00107.21 AEO57199.1 - 2.1e-10 40.2 0.0 4.6e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AEO57199.1 - 2.8e-06 27.0 0.1 0.00022 20.9 0.0 2.3 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain APH PF01636.18 AEO57200.1 - 5.1e-18 65.6 1.0 5.1e-18 65.6 0.7 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 AEO57200.1 - 0.00087 18.9 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Esterase_phd PF10503.4 AEO57203.1 - 1.4e-22 80.0 1.1 1.4e-22 80.0 0.8 1.5 2 0 0 2 2 2 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 AEO57203.1 - 2.2e-13 49.9 0.2 2.9e-13 49.5 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 AEO57203.1 - 5.7e-06 26.1 0.2 8.3e-06 25.6 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 AEO57203.1 - 0.0027 16.5 0.1 0.0036 16.0 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_1 PF00561.15 AEO57203.1 - 0.0038 16.8 0.1 0.0052 16.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 AEO57203.1 - 0.0066 16.3 0.3 0.015 15.2 0.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 AEO57203.1 - 0.027 14.0 0.5 0.072 12.6 0.1 1.8 1 1 1 2 2 2 0 alpha/beta hydrolase fold Esterase PF00756.15 AEO57203.1 - 0.091 12.1 0.4 0.12 11.7 0.3 1.3 1 1 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.11 AEO57203.1 - 0.13 11.6 0.2 2.9 7.2 0.2 2.5 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase Alpha-amylase PF00128.19 AEO57204.1 - 6.8e-97 324.6 0.0 9.9e-97 324.1 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 AEO57204.1 - 0.0062 15.4 0.0 0.014 14.3 0.0 1.5 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme Sugar_tr PF00083.19 AEO57205.1 - 1.4e-86 290.8 26.0 1.7e-86 290.6 18.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO57205.1 - 9.1e-17 60.7 28.6 9.1e-17 60.7 19.8 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.13 AEO57206.1 - 4.2e-10 39.3 9.3 6.7e-09 35.5 6.9 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 AEO57206.1 - 0.00062 18.7 0.1 0.0012 17.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2306 PF10067.4 AEO57207.1 - 4.4e-11 42.8 2.6 4.4e-11 42.8 1.8 2.1 3 0 0 3 3 3 1 Predicted membrane protein (DUF2306) DUF420 PF04238.7 AEO57207.1 - 0.0046 16.9 0.1 0.012 15.5 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF420) PrgI PF12666.2 AEO57207.1 - 0.0085 16.2 0.5 0.0085 16.2 0.3 2.2 2 0 0 2 2 2 1 PrgI family protein Abhydrolase_3 PF07859.8 AEO57209.1 - 1.3e-23 83.7 0.2 1.8e-23 83.2 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 AEO57209.1 - 1.1e-09 37.4 0.0 1.7e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 AEO57209.1 - 5.5e-05 22.4 0.0 8.6e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 AEO57209.1 - 0.019 14.7 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Fungal_trans PF04082.13 AEO57210.1 - 1.4e-17 63.4 0.3 6.8e-17 61.1 0.1 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain PgaD PF13994.1 AEO57210.1 - 0.02 14.3 0.0 0.16 11.4 0.0 2.2 2 0 0 2 2 2 0 PgaD-like protein RIX1 PF08167.7 AEO57210.1 - 0.077 12.6 0.0 0.27 10.8 0.0 1.9 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis ABC_membrane PF00664.18 AEO57211.1 - 4.4e-79 265.7 26.5 4.3e-41 141.1 8.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 AEO57211.1 - 1.6e-50 170.9 0.0 8.1e-33 113.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.1 AEO57211.1 - 2.1e-09 36.7 0.4 0.00024 20.5 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 AEO57211.1 - 5.4e-09 36.3 2.0 2.8e-05 24.1 0.1 2.8 2 1 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 AEO57211.1 - 4.6e-08 32.4 0.1 0.0038 16.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 SMC_N PF02463.14 AEO57211.1 - 5.5e-08 32.3 2.2 0.013 14.7 0.0 4.1 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.7 AEO57211.1 - 5.7e-08 32.0 0.3 0.0021 17.1 0.0 3.4 2 1 0 2 2 2 2 Zeta toxin AAA_21 PF13304.1 AEO57211.1 - 7.1e-08 32.7 0.0 0.54 10.1 0.0 3.3 3 0 0 3 3 3 3 AAA domain AAA_17 PF13207.1 AEO57211.1 - 6.9e-07 30.1 0.0 0.021 15.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 AEO57211.1 - 9.8e-07 28.9 0.1 0.041 14.0 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 AEO57211.1 - 2.5e-06 27.0 0.7 0.091 12.1 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.1 AEO57211.1 - 0.00014 21.7 0.0 0.15 11.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 AEO57211.1 - 0.00077 19.0 0.2 1.6 8.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 AEO57211.1 - 0.0012 18.5 1.4 0.93 9.2 0.0 3.6 3 0 0 3 3 3 1 Part of AAA domain MobB PF03205.9 AEO57211.1 - 0.0013 18.4 0.6 1 9.0 0.0 3.2 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 AEO57211.1 - 0.0013 18.2 1.5 2.2 7.6 0.1 3.5 3 0 0 3 3 3 1 AAA-like domain DUF87 PF01935.12 AEO57211.1 - 0.0013 18.5 0.7 0.68 9.7 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 ABC_ATPase PF09818.4 AEO57211.1 - 0.0014 17.2 0.2 0.28 9.7 0.1 3.2 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_23 PF13476.1 AEO57211.1 - 0.0024 18.2 0.0 1 9.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 AEO57211.1 - 0.0028 17.9 0.0 2.5 8.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.15 AEO57211.1 - 0.0039 15.9 0.0 1.6 7.3 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_15 PF13175.1 AEO57211.1 - 0.0066 15.5 0.0 2.2 7.2 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain PRK PF00485.13 AEO57211.1 - 0.0069 15.9 0.1 0.61 9.6 0.0 2.5 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_5 PF07728.9 AEO57211.1 - 0.0084 15.8 0.1 2.6 7.7 0.0 3.0 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA PF00004.24 AEO57211.1 - 0.0086 16.2 1.0 5.3 7.2 0.0 3.7 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 AEO57211.1 - 0.011 16.2 0.1 5.9 7.4 0.0 3.4 3 0 0 3 3 3 0 Miro-like protein AAA_14 PF13173.1 AEO57211.1 - 0.011 15.6 0.0 4.7 7.1 0.0 3.0 3 0 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.20 AEO57211.1 - 0.015 14.7 0.6 0.52 9.7 0.0 2.5 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain APS_kinase PF01583.15 AEO57211.1 - 0.015 14.9 0.0 4.9 6.7 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase MMR_HSR1 PF01926.18 AEO57211.1 - 0.023 14.6 0.6 2.5 8.0 0.0 2.9 2 1 0 2 2 2 0 50S ribosome-binding GTPase KaiC PF06745.8 AEO57211.1 - 0.041 13.0 0.9 1.4 7.9 0.1 2.3 2 0 0 2 2 2 0 KaiC AAA_28 PF13521.1 AEO57211.1 - 0.048 13.6 0.0 0.42 10.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 AEO57211.1 - 0.056 13.1 0.2 11 5.6 0.0 2.4 2 0 0 2 2 2 0 NACHT domain NB-ARC PF00931.17 AEO57211.1 - 0.062 12.1 0.7 3.4 6.4 0.1 2.2 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.17 AEO57211.1 - 0.086 13.0 0.2 9.7 6.4 0.0 3.0 3 0 0 3 3 3 0 RNA helicase Rad17 PF03215.10 AEO57211.1 - 0.15 10.7 0.0 0.31 9.6 0.0 1.4 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein peroxidase PF00141.18 AEO57212.1 - 2.2e-87 292.3 0.0 2.2e-45 154.9 0.0 2.3 2 0 0 2 2 2 2 Peroxidase Zn_clus PF00172.13 AEO57213.1 - 0.0021 17.9 9.6 0.0035 17.2 6.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 AEO57213.1 - 0.12 11.2 0.0 1.8 7.3 0.0 2.2 1 1 0 1 1 1 0 Fungal specific transcription factor domain Serglycin PF04360.7 AEO57213.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Serglycin Mito_fiss_reg PF05308.6 AEO57213.1 - 1.1 8.5 6.1 2.1 7.6 4.2 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator Alpha-amylase PF00128.19 AEO57214.1 - 7.2e-95 318.0 0.0 1.2e-94 317.3 0.0 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 AEO57214.1 - 0.0064 15.4 0.0 0.0094 14.8 0.0 1.1 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme Sugar_tr PF00083.19 AEO57215.1 - 1.6e-82 277.5 19.3 1.8e-82 277.3 13.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO57215.1 - 4.4e-18 65.1 39.3 6.2e-17 61.3 14.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 AEO57215.1 - 1.2e-08 33.8 19.8 2.8e-06 26.0 1.9 2.9 2 1 1 3 3 3 2 MFS/sugar transport protein Folate_carrier PF01770.13 AEO57215.1 - 0.00032 19.3 7.6 0.0024 16.4 5.3 1.9 1 1 0 1 1 1 1 Reduced folate carrier 5_nucleotid_C PF02872.13 AEO57216.1 - 4.3e-31 107.9 0.1 8.5e-31 107.0 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 AEO57216.1 - 1.6e-11 44.0 0.7 1.1e-10 41.2 0.3 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase YmdB PF13277.1 AEO57216.1 - 0.0047 15.9 0.0 0.0075 15.3 0.0 1.4 1 0 0 1 1 1 1 YmdB-like protein PGA_cap PF09587.5 AEO57216.1 - 0.024 13.9 0.0 0.056 12.7 0.0 1.6 1 1 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap DIT1_PvcA PF05141.7 AEO57217.1 - 7.5e-89 297.7 0.0 1.1e-88 297.2 0.0 1.2 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein p450 PF00067.17 AEO57217.1 - 8.8e-58 195.9 0.0 1.4e-57 195.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF995 PF06191.7 AEO57217.1 - 0.1 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF995) Ctr PF04145.10 AEO57218.1 - 1.4e-43 148.3 0.4 1.8e-43 148.0 0.3 1.1 1 0 0 1 1 1 1 Ctr copper transporter family YfhO PF09586.5 AEO57218.1 - 2.1 6.2 8.8 1.8 6.5 4.0 1.8 2 0 0 2 2 2 0 Bacterial membrane protein YfhO PQQ_3 PF13570.1 AEO57219.1 - 0.092 13.0 4.2 19 5.7 0.0 4.2 4 0 0 4 4 4 0 PQQ-like domain SurE PF01975.12 AEO57220.1 - 1.2e-28 99.7 0.1 1.8e-28 99.1 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE RVT_1 PF00078.22 AEO57221.1 - 0.00026 20.4 0.3 0.00029 20.2 0.2 1.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3786 PF12654.2 AEO57221.1 - 0.016 14.5 0.1 0.018 14.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3786) Spt20 PF12090.3 AEO57222.1 - 0.38 10.0 6.5 0.07 12.4 1.4 1.9 2 0 0 2 2 2 0 Spt20 family PH_4 PF15404.1 AEO57222.1 - 0.61 9.5 9.8 0.055 12.9 0.8 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain Suf PF05843.9 AEO57222.1 - 1.1 8.9 15.1 0.05 13.3 5.7 1.9 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) AAA_23 PF13476.1 AEO57222.1 - 3.3 7.9 10.6 2 8.6 3.5 2.1 2 0 0 2 2 2 0 AAA domain vMSA PF00695.14 AEO57222.1 - 3.8 6.6 5.1 6.2 5.9 3.5 1.3 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus TORC_M PF12885.2 AEO57222.1 - 4.3 7.0 8.3 0.18 11.5 1.2 1.9 2 0 0 2 2 2 0 Transducer of regulated CREB activity middle domain DUF3381 PF11861.3 AEO57222.1 - 7.2 6.0 23.7 5.1 6.5 4.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) eIF-3_zeta PF05091.7 AEO57222.1 - 7.9 4.9 17.8 0.087 11.4 4.6 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) MFS_1 PF07690.11 AEO57223.1 - 8.8e-38 129.9 58.0 1.8e-36 125.6 39.9 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily WBP-1 PF11669.3 AEO57223.1 - 0.018 15.0 0.4 0.075 13.1 0.1 2.1 2 0 0 2 2 2 0 WW domain-binding protein 1 Corona_S2 PF01601.11 AEO57223.1 - 0.12 10.4 1.0 0.17 9.9 0.7 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Fungal_trans_2 PF11951.3 AEO57224.1 - 1.7e-31 109.2 0.5 6.4e-31 107.2 0.4 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO57224.1 - 1.6e-07 31.0 6.9 2.9e-07 30.3 4.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Vma12 PF11712.3 AEO57225.1 - 0.04 13.6 0.0 0.057 13.1 0.0 1.4 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Adeno_E3_CR2 PF02439.10 AEO57225.1 - 0.12 11.9 0.3 0.25 10.9 0.2 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF4328 PF14219.1 AEO57225.1 - 0.13 11.5 0.1 0.19 11.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) SKG6 PF08693.5 AEO57225.1 - 1.2 8.5 7.5 0.074 12.3 1.3 2.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Thioredoxin PF00085.15 AEO57228.1 - 9.6e-27 92.7 0.0 1.1e-26 92.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 AEO57228.1 - 7e-06 26.0 0.0 2e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 AEO57228.1 - 9.7e-06 25.7 0.2 0.00027 21.1 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 AEO57228.1 - 0.00011 22.1 0.0 0.00018 21.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 AEO57228.1 - 0.0012 18.5 0.1 0.0035 17.0 0.0 1.7 1 1 0 1 1 1 1 AhpC/TSA family DIM1 PF02966.11 AEO57228.1 - 0.0023 17.4 0.0 0.0029 17.1 0.0 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_9 PF14595.1 AEO57228.1 - 0.028 13.9 0.0 0.044 13.3 0.0 1.3 1 1 0 1 1 1 0 Thioredoxin HyaE PF07449.6 AEO57228.1 - 0.12 12.3 0.1 0.24 11.3 0.0 1.5 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE SnoaL_4 PF13577.1 AEO57229.1 - 8.9e-09 35.3 0.0 1.4e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain Cyclin PF08613.6 AEO57230.1 - 8.5e-18 65.1 0.0 2.1e-17 63.8 0.0 1.7 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 AEO57230.1 - 1.4e-05 24.6 0.0 2.4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Arrestin_C PF02752.17 AEO57231.1 - 4.6e-17 62.3 0.0 2.7e-16 59.9 0.0 2.3 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 AEO57231.1 - 8.1e-07 28.9 6.8 0.00035 20.4 0.0 3.1 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain MIP-T3 PF10243.4 AEO57231.1 - 0.019 13.4 13.2 0.037 12.5 9.1 1.4 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Ycf1 PF05758.7 AEO57231.1 - 0.11 10.1 0.1 0.14 9.8 0.1 1.1 1 0 0 1 1 1 0 Ycf1 DUF2413 PF10310.4 AEO57231.1 - 1.7 7.3 6.4 2.6 6.7 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Phage_Gp23 PF10669.4 AEO57231.1 - 2.4 8.2 8.1 4.4 7.4 5.6 1.3 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Aldo_ket_red PF00248.16 AEO57232.1 - 2.6e-24 85.5 0.0 3.1e-24 85.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Chs3p PF12271.3 AEO57233.1 - 1.4e-140 467.3 12.7 1.6e-140 467.1 8.8 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit DUF3382 PF11862.3 AEO57233.1 - 4.8 7.1 12.0 0.25 11.2 3.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3382) DUF3716 PF12511.3 AEO57234.1 - 2.1e-08 33.6 4.4 3.8e-08 32.8 3.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) IncA PF04156.9 AEO57234.1 - 0.0056 16.3 1.5 0.0056 16.3 1.1 1.8 2 0 0 2 2 2 1 IncA protein Secretin_N_2 PF07655.8 AEO57234.1 - 2.3 8.6 7.2 0.5 10.7 1.3 2.7 2 0 0 2 2 2 0 Secretin N-terminal domain Ribosomal_S6 PF01250.12 AEO57235.1 - 3.1e-11 42.9 0.0 3.6e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 Cullin_binding PF03556.10 AEO57236.1 - 1.8e-27 95.7 1.3 2.6e-27 95.2 0.9 1.3 1 0 0 1 1 1 1 Cullin binding PX PF00787.19 AEO57237.1 - 7.6e-19 67.5 0.2 1.5e-18 66.6 0.1 1.5 1 0 0 1 1 1 1 PX domain ADIP PF11559.3 AEO57238.1 - 0.038 13.8 11.2 1 9.2 0.0 2.8 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.4 AEO57238.1 - 0.06 13.2 8.4 0.071 12.9 0.9 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF972 PF06156.8 AEO57238.1 - 0.15 12.4 3.5 3 8.2 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF972) HOOK PF05622.7 AEO57238.1 - 0.23 9.2 7.6 1.7 6.3 0.1 2.2 2 0 0 2 2 2 0 HOOK protein Spc24 PF08286.6 AEO57238.1 - 0.31 10.7 4.6 3.1 7.5 0.0 2.4 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 TBPIP PF07106.8 AEO57238.1 - 0.38 10.2 8.1 2.9 7.4 1.5 2.3 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DivIC PF04977.10 AEO57238.1 - 0.48 9.9 12.1 0.38 10.2 4.5 2.3 2 0 0 2 2 2 0 Septum formation initiator IncA PF04156.9 AEO57238.1 - 0.55 9.7 7.0 7.9 6.0 0.1 2.3 2 0 0 2 2 2 0 IncA protein APG6 PF04111.7 AEO57238.1 - 1 8.3 7.2 2.7 6.9 1.9 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 MerR_2 PF13591.1 AEO57238.1 - 1.8 8.2 7.5 0.11 12.0 0.8 2.3 2 0 0 2 2 2 0 MerR HTH family regulatory protein Spc7 PF08317.6 AEO57238.1 - 2.3 6.8 8.0 4.8 5.7 0.2 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF2802 PF10975.3 AEO57238.1 - 4.3 7.1 6.9 2.2 8.1 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) Prefoldin_2 PF01920.15 AEO57238.1 - 7.9 6.2 11.6 4.2 7.1 3.9 2.5 2 0 0 2 2 2 0 Prefoldin subunit Ribosomal_L18e PF00828.14 AEO57239.1 - 5e-14 52.7 0.0 7.9e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 PRA1 PF03208.14 AEO57242.1 - 0.03 13.6 0.1 0.031 13.6 0.1 1.0 1 0 0 1 1 1 0 PRA1 family protein DUF4131 PF13567.1 AEO57242.1 - 1.3 8.4 5.7 1.4 8.3 3.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Hum_adeno_E3A PF05393.6 AEO57242.1 - 2 8.1 4.9 2.5 7.8 3.4 1.1 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein NmrA PF05368.8 AEO57243.1 - 0.089 12.0 0.0 0.54 9.4 0.0 1.9 1 1 0 1 1 1 0 NmrA-like family GST_N PF02798.15 AEO57244.1 - 1.2e-08 34.9 0.0 7.1e-08 32.5 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 AEO57244.1 - 5e-07 29.5 0.0 1.3e-06 28.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 AEO57244.1 - 6.2e-07 29.3 0.0 1.4e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 AEO57244.1 - 1.3e-06 28.7 0.0 2.2e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 AEO57244.1 - 1.5e-06 28.3 0.0 2.8e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 AEO57244.1 - 4.1e-05 23.4 0.0 7.5e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PBP1_TM PF14812.1 AEO57246.1 - 0.024 14.9 0.6 0.024 14.9 0.4 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MFMR PF07777.6 AEO57246.1 - 0.098 12.5 0.5 0.18 11.7 0.3 1.3 1 0 0 1 1 1 0 G-box binding protein MFMR Abhydrolase_5 PF12695.2 AEO57247.1 - 4.7e-18 65.3 0.2 6.9e-18 64.7 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AEO57247.1 - 9.1e-13 48.6 8.4 3.7e-11 43.3 5.8 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 AEO57247.1 - 6e-07 28.9 0.5 0.029 13.6 0.1 2.9 3 0 0 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 AEO57247.1 - 1.9e-05 24.3 2.6 5.8e-05 22.7 1.6 1.6 1 1 1 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.15 AEO57247.1 - 0.014 14.8 1.6 0.019 14.3 0.0 1.8 2 0 0 2 2 2 0 Putative esterase Lipase_3 PF01764.20 AEO57247.1 - 0.015 14.8 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Thioesterase PF00975.15 AEO57247.1 - 0.029 14.6 1.6 0.04 14.1 0.2 1.8 2 0 0 2 2 2 0 Thioesterase domain Abhydrolase_2 PF02230.11 AEO57247.1 - 0.047 13.1 0.0 3 7.2 0.0 2.3 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase Pex14_N PF04695.8 AEO57247.1 - 0.053 13.5 2.5 0.085 12.9 1.7 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Abhydrolase_3 PF07859.8 AEO57247.1 - 0.091 12.3 0.9 0.17 11.4 0.6 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.13 AEO57247.1 - 0.097 11.9 0.8 0.27 10.4 0.2 2.1 2 1 0 2 2 2 0 Dienelactone hydrolase family PhoPQ_related PF10142.4 AEO57247.1 - 0.16 10.4 0.2 0.54 8.6 0.0 1.9 3 0 0 3 3 3 0 PhoPQ-activated pathogenicity-related protein K_channel_TID PF07941.6 AEO57247.1 - 4.4 7.5 10.6 1.4 9.1 3.9 2.8 1 1 1 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain FAD_binding_3 PF01494.14 AEO57248.1 - 2.5e-74 250.4 0.0 3.2e-74 250.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 AEO57248.1 - 2.9e-44 150.6 0.0 4.7e-44 149.9 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_oxidored PF12831.2 AEO57248.1 - 2.6e-05 23.5 0.1 3.9e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 AEO57248.1 - 0.00079 18.5 0.0 0.0014 17.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 AEO57248.1 - 0.0011 17.8 0.2 0.0055 15.6 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 AEO57248.1 - 0.0017 18.4 0.0 0.006 16.6 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 AEO57248.1 - 0.0019 17.1 6.1 0.0044 15.9 0.1 2.6 2 1 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AEO57248.1 - 0.0084 16.1 0.1 0.032 14.2 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 AEO57248.1 - 0.011 14.7 0.7 0.2 10.7 0.0 2.8 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 AEO57248.1 - 0.029 14.7 0.0 0.065 13.6 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 AEO57248.1 - 0.029 13.1 0.1 2.2 7.0 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase AlaDh_PNT_C PF01262.16 AEO57248.1 - 0.039 13.5 0.0 0.072 12.6 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF2369 PF10179.4 AEO57248.1 - 0.24 10.4 0.0 0.41 9.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2369) NAD_binding_10 PF13460.1 AEO57249.1 - 6.4e-22 78.4 0.2 1.1e-12 48.4 0.0 2.3 1 1 1 2 2 2 2 NADH(P)-binding NmrA PF05368.8 AEO57249.1 - 0.0015 17.8 0.0 0.0025 17.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 AEO57249.1 - 0.0073 15.7 0.0 0.013 14.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 AEO57249.1 - 0.018 14.9 0.1 0.018 14.9 0.0 1.9 2 0 0 2 2 2 0 short chain dehydrogenase Abhydrolase_6 PF12697.2 AEO57249.1 - 0.56 10.0 5.1 1.5 8.6 3.6 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Osmo_MPGsynth PF09488.5 AEO57250.1 - 1.8e-119 398.8 0.0 4.5e-80 269.1 0.0 2.0 2 0 0 2 2 2 2 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) Spore_YhcN_YlaJ PF09580.5 AEO57250.1 - 0.0078 16.3 8.1 0.0078 16.3 5.6 2.2 2 0 0 2 2 2 1 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) CobT PF06213.7 AEO57250.1 - 1.2 8.1 9.1 0.8 8.7 2.5 2.4 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Zip PF02535.17 AEO57250.1 - 1.4 7.8 7.1 18 4.1 4.9 2.1 1 1 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.11 AEO57250.1 - 1.4 8.7 7.6 3.8 7.3 5.3 1.6 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region zf-trcl PF13451.1 AEO57251.1 - 1.1 8.9 3.8 1.8 8.2 2.6 1.3 1 0 0 1 1 1 0 Probable zinc-binding domain SGL PF08450.7 AEO57253.1 - 0.018 14.4 0.8 1.2 8.4 0.1 2.8 1 1 1 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region DUF4394 PF14339.1 AEO57253.1 - 0.039 13.2 1.5 3.3 6.9 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4394) NHL PF01436.16 AEO57253.1 - 0.061 13.3 3.8 4 7.5 0.1 3.2 3 0 0 3 3 3 0 NHL repeat Ank_5 PF13857.1 AEO57254.1 - 9.7e-16 57.4 0.1 2.6e-10 40.1 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 AEO57254.1 - 4.5e-15 55.7 0.3 2.2e-08 34.3 0.1 4.0 4 0 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 AEO57254.1 - 1.1e-14 54.4 0.6 3.5e-08 33.7 0.0 4.8 5 1 0 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.25 AEO57254.1 - 1.9e-11 43.1 0.1 2.8e-06 26.8 0.0 4.3 4 1 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 AEO57254.1 - 2.2e-09 36.6 1.2 0.00023 21.0 0.0 4.5 6 0 0 6 6 6 2 Ankyrin repeat Macoilin PF09726.4 AEO57254.1 - 2.9 6.0 7.6 4.1 5.5 5.3 1.1 1 0 0 1 1 1 0 Transmembrane protein GPI-anchored PF10342.4 AEO57255.1 - 2.4e-18 66.3 0.5 2.4e-18 66.3 0.3 2.4 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Pertactin PF03212.9 AEO57255.1 - 0.054 13.2 0.0 0.054 13.2 0.0 2.2 1 1 1 2 2 2 0 Pertactin Hex_IIIa PF02455.11 AEO57255.1 - 0.084 11.5 3.9 0.11 11.1 2.7 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Mucin PF01456.12 AEO57255.1 - 1.7 8.3 30.6 0.25 11.1 18.3 1.7 2 0 0 2 2 2 0 Mucin-like glycoprotein DNA_pol_viral_N PF00242.12 AEO57255.1 - 3.7 6.4 7.8 4.4 6.2 5.4 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF1675 PF07897.6 AEO57255.1 - 4.2 7.1 11.4 6.2 6.6 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Macoilin PF09726.4 AEO57255.1 - 4.3 5.5 8.5 4.7 5.3 5.9 1.0 1 0 0 1 1 1 0 Transmembrane protein Aldo_ket_red PF00248.16 AEO57257.1 - 5.5e-68 228.8 0.0 6.7e-68 228.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family OHCU_decarbox PF09349.5 AEO57258.1 - 9.6e-34 116.9 4.0 8.9e-19 68.3 0.1 2.1 2 0 0 2 2 2 2 OHCU decarboxylase NUT_N PF12881.2 AEO57258.1 - 0.77 8.8 3.8 1.2 8.2 2.6 1.3 1 0 0 1 1 1 0 NUT protein N terminus Med25_VWA PF11265.3 AEO57259.1 - 0.21 10.5 0.0 0.32 9.9 0.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 25 von Willebrand factor type A 4HBT_3 PF13622.1 AEO57260.1 - 4e-40 138.1 3.9 5.2e-40 137.8 2.7 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Sigma70_r3 PF04539.11 AEO57260.1 - 0.1 12.5 0.3 0.17 11.7 0.2 1.4 1 0 0 1 1 1 0 Sigma-70 region 3 COX5B PF01215.14 AEO57261.1 - 6.6e-40 135.9 0.0 8.4e-40 135.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb DUF4604 PF15377.1 AEO57262.1 - 3.6e-28 98.7 22.5 5.6e-28 98.1 15.6 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4604) Lin-8 PF03353.10 AEO57262.1 - 0.0035 16.6 5.1 0.0038 16.5 3.5 1.2 1 0 0 1 1 1 1 Ras-mediated vulval-induction antagonist DUF3292 PF11696.3 AEO57262.1 - 0.097 10.5 4.5 0.14 9.9 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) FimP PF09766.4 AEO57262.1 - 1.2 8.1 7.2 1.8 7.5 5.0 1.3 1 0 0 1 1 1 0 Fms-interacting protein FCP1_C PF09309.5 AEO57262.1 - 1.6 7.9 17.2 0.62 9.3 10.1 1.6 1 1 1 2 2 2 0 FCP1, C-terminal Ycf1 PF05758.7 AEO57262.1 - 4.6 4.8 5.0 5 4.7 3.4 1.1 1 0 0 1 1 1 0 Ycf1 Ank_2 PF12796.2 AEO57263.1 - 1.6e-43 146.9 2.7 8.7e-16 58.0 0.1 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 AEO57263.1 - 6.4e-31 104.6 5.6 4.7e-11 41.9 0.0 4.8 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 AEO57263.1 - 3.5e-28 97.4 0.9 4.6e-12 46.0 0.1 4.4 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 AEO57263.1 - 6.1e-23 80.3 3.1 4.8e-10 39.3 0.1 5.2 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 AEO57263.1 - 1.9e-18 64.7 0.2 1e-07 31.4 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Glyco_hydro_16 PF00722.16 AEO57264.1 - 1.2e-45 155.0 4.4 1.8e-45 154.4 3.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.14 AEO57264.1 - 3.3 7.7 18.9 0.083 12.8 7.8 2.2 2 0 0 2 2 2 0 Chitin recognition protein Herpes_capsid PF06112.6 AEO57264.1 - 7.1 6.6 12.1 11 6.0 8.4 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Myb_DNA-bind_6 PF13921.1 AEO57265.1 - 8.5e-11 41.8 0.4 8.2e-06 25.8 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 AEO57265.1 - 3.3e-10 39.8 1.6 3.8e-06 26.8 0.4 2.6 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 AEO57266.1 - 0.00092 19.2 0.2 0.0017 18.4 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 AEO57266.1 - 0.025 14.6 0.1 0.26 11.3 0.3 2.3 2 0 0 2 2 2 0 Myb-like DNA-binding domain ILVD_EDD PF00920.16 AEO57268.1 - 3.4e-190 632.9 1.2 4e-190 632.6 0.8 1.0 1 0 0 1 1 1 1 Dehydratase family InvH PF04741.7 AEO57268.1 - 0.21 11.4 0.0 0.35 10.7 0.0 1.2 1 0 0 1 1 1 0 InvH outer membrane lipoprotein Glyco_transf_15 PF01793.11 AEO57269.1 - 8.3e-132 439.1 2.4 1.1e-131 438.7 1.6 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Tyrosinase PF00264.15 AEO57270.1 - 1e-32 114.1 0.0 1.4e-32 113.6 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase DnaJ PF00226.26 AEO57271.1 - 0.17 11.6 0.0 2.7 7.8 0.0 2.2 2 0 0 2 2 2 0 DnaJ domain RNA_pol_Rpb2_6 PF00562.23 AEO57272.1 - 0.0094 14.7 0.0 0.011 14.5 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 PhzC-PhzF PF02567.11 AEO57273.1 - 1.5e-40 139.2 0.5 3.6e-39 134.6 0.4 2.6 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein Prp19 PF08606.6 AEO57273.1 - 4.5e-31 106.3 1.7 4.5e-31 106.3 1.2 1.7 2 0 0 2 2 2 1 Prp19/Pso4-like WD40 PF00400.27 AEO57273.1 - 4.7e-10 38.9 4.4 0.00018 21.2 0.0 5.8 7 0 0 7 7 7 2 WD domain, G-beta repeat eIF2A PF08662.6 AEO57273.1 - 5.9e-06 26.1 0.1 0.0069 16.1 0.0 2.7 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A zf-Nse PF11789.3 AEO57273.1 - 0.00017 21.0 0.0 0.00036 19.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Peripla_BP_2 PF01497.13 AEO57273.1 - 0.0042 16.2 0.7 0.34 10.0 0.1 3.0 3 0 0 3 3 3 1 Periplasmic binding protein Rtf2 PF04641.7 AEO57273.1 - 0.036 13.2 0.0 0.062 12.4 0.0 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger zf-RING_5 PF14634.1 AEO57274.1 - 0.0051 16.5 3.1 0.015 15.0 2.2 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 AEO57274.1 - 0.011 15.7 0.6 0.011 15.7 0.4 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 AEO57274.1 - 0.021 14.5 0.1 0.049 13.3 0.1 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.20 AEO57274.1 - 0.022 14.4 2.6 0.055 13.1 1.8 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AEO57274.1 - 0.21 11.4 2.7 0.17 11.7 0.4 1.9 2 0 0 2 2 2 0 Ring finger domain Peptidase_C14 PF00656.17 AEO57275.1 - 0.0041 16.8 0.0 0.027 14.1 0.0 2.1 2 1 0 2 2 2 1 Caspase domain Raptor_N PF14538.1 AEO57275.1 - 0.0077 16.0 0.7 0.17 11.7 0.0 2.4 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain DUF294 PF03445.8 AEO57275.1 - 0.026 14.1 0.2 0.51 9.9 0.0 2.5 2 0 0 2 2 2 0 Putative nucleotidyltransferase DUF294 Peptidase_C11 PF03415.9 AEO57275.1 - 0.071 12.0 0.1 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 Clostripain family FAD_binding_3 PF01494.14 AEO57277.1 - 1.4e-13 50.6 1.0 4.2e-07 29.3 0.0 2.8 3 1 0 3 3 3 2 FAD binding domain DAO PF01266.19 AEO57277.1 - 5.8e-07 28.7 0.0 0.021 13.7 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AEO57277.1 - 2.2e-05 24.3 0.0 6.9e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 AEO57277.1 - 4.3e-05 23.8 0.1 0.026 14.8 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 AEO57277.1 - 0.0014 17.6 0.0 0.6 8.9 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.9 AEO57277.1 - 0.004 15.6 0.0 0.81 8.0 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_9 PF13454.1 AEO57277.1 - 0.02 14.6 0.4 0.74 9.5 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 AEO57277.1 - 0.071 11.7 0.2 5.9 5.4 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Thi4 PF01946.12 AEO57277.1 - 0.15 11.1 0.0 0.3 10.1 0.0 1.4 1 0 0 1 1 1 0 Thi4 family MFS_1 PF07690.11 AEO57278.1 - 6.3e-35 120.5 31.6 2.4e-34 118.5 22.1 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily ESSS PF10183.4 AEO57278.1 - 0.006 16.9 0.2 0.022 15.1 0.1 2.0 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) MFS_1 PF07690.11 AEO57279.1 - 4.1e-47 160.5 49.9 4.1e-47 160.5 34.6 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 AEO57279.1 - 0.058 12.8 6.7 0.11 12.0 3.9 2.1 1 1 0 1 1 1 0 Ion channel regulatory protein UNC-93 Fungal_trans PF04082.13 AEO57280.1 - 2.3e-15 56.1 3.1 2.3e-15 56.1 2.2 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Daxx PF03344.10 AEO57281.1 - 0.54 8.6 13.8 0.67 8.3 9.5 1.1 1 0 0 1 1 1 0 Daxx Family Nucleoplasmin PF03066.10 AEO57281.1 - 0.64 9.5 14.8 1.1 8.8 10.2 1.3 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 AEO57281.1 - 0.75 9.0 5.0 1.1 8.4 3.5 1.1 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.7 AEO57281.1 - 0.82 7.5 12.4 1 7.1 8.6 1.1 1 0 0 1 1 1 0 Nop14-like family CENP-T PF15511.1 AEO57281.1 - 1.5 7.9 6.8 2.1 7.4 4.7 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T SDA1 PF05285.7 AEO57281.1 - 2 7.5 11.6 2.8 7.1 8.1 1.1 1 0 0 1 1 1 0 SDA1 TFIIF_alpha PF05793.7 AEO57281.1 - 3.4 5.9 13.1 4.6 5.4 9.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) HPP PF04982.8 AEO57282.1 - 2.2e-36 124.3 9.5 2.2e-36 124.3 6.6 1.4 2 0 0 2 2 2 1 HPP family RskA PF10099.4 AEO57282.1 - 1.5 8.5 9.2 0.31 10.7 1.3 2.7 2 1 1 3 3 3 0 Anti-sigma-K factor rskA HTH_29 PF13551.1 AEO57283.1 - 5.3e-05 23.3 0.0 6.6e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 AEO57283.1 - 0.11 13.3 0.2 0.19 12.5 0.1 1.5 1 1 0 1 1 1 0 Homeodomain-like domain IDO PF01231.13 AEO57284.1 - 4.3e-125 417.4 0.0 1.3e-124 415.9 0.0 1.7 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase Aminotran_5 PF00266.14 AEO57285.1 - 2.4e-07 29.8 0.0 9.7e-07 27.8 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class-V Methyltransf_24 PF13578.1 AEO57287.1 - 4.3e-08 33.9 0.0 7.3e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 AEO57287.1 - 1.6e-05 24.0 0.0 4.8e-05 22.5 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase Peptidase_C1 PF00112.18 AEO57290.1 - 1.5e-25 90.3 0.8 3.2e-25 89.2 0.6 1.5 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_A4 PF01828.12 AEO57291.1 - 3.2e-79 264.8 6.6 3.7e-79 264.6 4.6 1.0 1 0 0 1 1 1 1 Peptidase A4 family End_beta_barrel PF12195.3 AEO57291.1 - 1.8 8.3 6.9 13 5.6 0.7 3.0 3 0 0 3 3 3 0 Beta barrel domain of bacteriophage endosialidase Pkinase PF00069.20 AEO57293.1 - 4.9e-15 55.3 0.0 8.1e-15 54.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO57293.1 - 6.2e-09 35.3 0.0 1.2e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase CorA PF01544.13 AEO57293.1 - 0.03 13.3 9.6 0.3 10.0 0.1 3.0 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein FtsX PF02687.16 AEO57293.1 - 0.28 10.9 0.2 0.57 9.9 0.2 1.4 1 0 0 1 1 1 0 FtsX-like permease family COesterase PF00135.23 AEO57294.1 - 2.6e-96 323.4 0.0 3.3e-96 323.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 AEO57294.1 - 4.6e-06 26.3 0.0 2.7e-05 23.8 0.0 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 AEO57294.1 - 0.16 11.1 0.1 0.29 10.3 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family FAD_binding_4 PF01565.18 AEO57295.1 - 4.8e-17 61.7 1.8 9.4e-17 60.7 1.2 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 AEO57295.1 - 0.011 15.6 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Berberine and berberine like Integrase_Zn PF02022.14 AEO57296.1 - 0.057 12.8 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 Integrase Zinc binding domain DUF3795 PF12675.2 AEO57296.1 - 6.6 6.9 9.8 1.3e+02 2.8 6.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3795) Abhydrolase_6 PF12697.2 AEO57299.1 - 1.8e-29 103.2 1.0 2.2e-29 102.9 0.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO57299.1 - 1.3e-14 54.1 0.0 3e-14 52.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO57299.1 - 3.9e-11 42.9 0.0 1.9e-10 40.6 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 AEO57299.1 - 3.8e-06 26.2 0.0 5.9e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 AEO57299.1 - 0.00011 21.9 0.0 0.0015 18.3 0.0 2.8 3 1 0 3 3 3 1 Putative lysophospholipase Abhydrolase_4 PF08386.5 AEO57299.1 - 0.00021 21.1 0.0 0.00042 20.1 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein EHN PF06441.7 AEO57299.1 - 0.026 14.4 0.0 0.4 10.6 0.0 2.3 2 0 0 2 2 2 0 Epoxide hydrolase N terminus BAAT_C PF08840.6 AEO57299.1 - 0.15 11.7 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF3984 PF13136.1 AEO57300.1 - 0.0092 15.2 0.5 0.012 14.8 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3984) CDC45 PF02724.9 AEO57300.1 - 0.92 7.4 4.3 1 7.3 3.0 1.0 1 0 0 1 1 1 0 CDC45-like protein GRP PF07172.6 AEO57300.1 - 6 7.4 8.3 7.4 7.1 5.3 1.5 1 1 0 1 1 1 0 Glycine rich protein family O-FucT PF10250.4 AEO57301.1 - 5.8e-14 51.9 0.0 3.4e-10 39.5 0.0 2.7 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase WD40 PF00400.27 AEO57302.1 - 5.5e-22 76.7 13.1 1.5e-10 40.5 0.1 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 AEO57302.1 - 4.1e-18 65.0 0.0 8.7e-18 63.9 0.0 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Nucleoporin_N PF08801.6 AEO57302.1 - 0.011 14.5 0.4 0.25 10.0 0.2 2.5 1 1 1 2 2 2 0 Nup133 N terminal like Glyco_hydro_43 PF04616.9 AEO57303.1 - 6e-35 120.7 4.1 8e-35 120.3 2.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF1524 PF07510.6 AEO57304.1 - 1.7e-12 47.3 0.0 2.1e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) LHC PF00556.15 AEO57305.1 - 0.84 9.5 3.3 2 8.3 2.3 1.6 1 0 0 1 1 1 0 Antenna complex alpha/beta subunit Oxidored_q6 PF01058.17 AEO57306.1 - 1e-23 83.3 0.0 1.1e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Fungal_trans PF04082.13 AEO57307.1 - 6.6e-12 44.8 0.0 1e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 AEO57308.1 - 3.3e-29 101.6 33.0 3.3e-29 101.6 22.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO57308.1 - 1.3e-08 33.9 12.3 1.3e-08 33.9 8.5 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 AEO57308.1 - 5.7e-07 28.1 2.8 5.7e-07 28.1 2.0 2.0 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) adh_short PF00106.20 AEO57309.1 - 2.8e-18 66.3 0.4 3.8e-18 65.9 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO57309.1 - 7.7e-11 41.9 0.1 1.1e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 AEO57309.1 - 7.8e-06 25.8 0.0 1.2e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 AEO57309.1 - 0.0001 22.0 0.1 0.00021 20.9 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 AEO57309.1 - 0.0018 17.2 0.0 0.0033 16.3 0.0 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Amidoligase_2 PF12224.3 AEO57310.1 - 1.1e-16 61.2 0.0 4.5e-12 46.1 0.0 2.1 2 0 0 2 2 2 2 Putative amidoligase enzyme TBCC PF07986.7 AEO57310.1 - 0.15 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Tubulin binding cofactor C Thioredoxin PF00085.15 AEO57311.1 - 4.6e-23 80.8 0.0 6.5e-23 80.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 AEO57311.1 - 1.5e-07 31.3 0.0 2.4e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.1 AEO57311.1 - 4.5e-07 29.9 0.0 2.7e-05 24.1 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.1 AEO57311.1 - 5.3e-07 29.8 0.1 3.1e-06 27.3 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 AEO57311.1 - 1.4e-05 24.7 0.0 3.1e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 AEO57311.1 - 5.8e-05 22.6 0.0 8.5e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Redoxin Thioredoxin_9 PF14595.1 AEO57311.1 - 0.00089 18.8 0.0 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Glutaredoxin PF00462.19 AEO57311.1 - 0.018 15.0 0.1 0.041 13.8 0.0 1.7 1 1 0 1 1 1 0 Glutaredoxin Thioredoxin_4 PF13462.1 AEO57311.1 - 0.024 14.6 0.0 0.3 11.0 0.0 2.0 1 1 1 2 2 2 0 Thioredoxin Thioredoxin_3 PF13192.1 AEO57311.1 - 0.032 14.0 0.0 0.055 13.2 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain WD40 PF00400.27 AEO57312.1 - 6.1e-30 102.0 7.6 6e-10 38.6 0.0 7.7 7 1 0 7 7 7 5 WD domain, G-beta repeat eRF1_1 PF03463.10 AEO57313.1 - 5.6e-27 93.9 0.2 1.2e-26 92.8 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 AEO57313.1 - 8.5e-22 77.9 0.1 1.7e-21 76.9 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 AEO57313.1 - 1.8e-19 70.0 0.0 4e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 BCS1_N PF08740.6 AEO57314.1 - 3.5e-35 121.3 0.5 7e-35 120.3 0.4 1.5 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 AEO57314.1 - 1.1e-16 61.2 0.0 1.9e-15 57.2 0.0 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 AEO57314.1 - 9.7e-05 23.1 0.3 0.0019 19.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 AEO57314.1 - 0.00014 20.9 0.0 0.00028 20.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_11 PF13086.1 AEO57314.1 - 0.00029 20.4 0.0 0.00067 19.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 AEO57314.1 - 0.0023 17.6 0.3 0.0081 15.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 AEO57314.1 - 0.0026 17.4 1.1 0.017 14.8 0.0 2.7 3 0 0 3 3 3 1 Part of AAA domain AAA_25 PF13481.1 AEO57314.1 - 0.0029 17.0 0.3 0.0098 15.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 AEO57314.1 - 0.0081 16.1 1.5 0.013 15.5 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 AEO57314.1 - 0.014 14.8 0.0 0.044 13.1 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein KaiC PF06745.8 AEO57314.1 - 0.024 13.7 0.0 0.11 11.5 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_24 PF13479.1 AEO57314.1 - 0.032 13.8 0.1 0.073 12.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 AEO57314.1 - 0.05 13.7 0.2 0.22 11.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 AEO57314.1 - 0.3 11.4 0.0 0.3 11.4 0.0 2.9 2 1 0 2 2 1 0 AAA domain Methyltransf_11 PF08241.7 AEO57315.1 - 1.1e-14 54.7 0.0 2.2e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO57315.1 - 1e-13 51.3 0.0 1.4e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO57315.1 - 5.2e-12 45.5 0.0 7.8e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO57315.1 - 6.4e-12 45.8 0.0 1.3e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO57315.1 - 2.4e-11 43.7 0.0 4.3e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO57315.1 - 1.7e-10 41.1 0.0 3e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO57315.1 - 6.3e-10 39.6 0.0 1.4e-09 38.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 AEO57315.1 - 4.2e-08 32.5 0.0 6.2e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 AEO57315.1 - 5.4e-05 22.6 0.0 0.0001 21.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 AEO57315.1 - 0.00026 20.1 0.0 0.0004 19.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_PK PF05891.7 AEO57315.1 - 0.0046 16.2 0.0 0.0074 15.6 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase CheR PF01739.13 AEO57315.1 - 0.025 13.8 0.0 0.15 11.2 0.0 2.1 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain MetW PF07021.7 AEO57315.1 - 0.043 13.1 0.0 0.065 12.6 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PCMT PF01135.14 AEO57315.1 - 0.049 13.1 0.0 0.086 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) ABC2_membrane PF01061.19 AEO57316.1 - 2.5e-89 297.9 63.0 1.3e-46 158.4 10.8 3.2 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 AEO57316.1 - 9.5e-38 129.5 0.0 1.9e-17 63.8 0.0 2.7 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.7 AEO57316.1 - 8.9e-36 121.6 0.1 2.2e-27 94.6 0.0 3.0 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 AEO57316.1 - 1.3e-19 70.0 0.0 3.1e-19 68.8 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 AEO57316.1 - 4.9e-10 39.1 0.0 4.8e-06 26.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 AEO57316.1 - 2e-07 30.9 0.1 0.00022 21.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 AEO57316.1 - 5.2e-05 22.4 0.1 0.0013 17.9 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 AEO57316.1 - 6.4e-05 23.7 0.0 0.045 14.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 AEO57316.1 - 9.3e-05 21.8 0.9 0.0085 15.6 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.2 AEO57316.1 - 0.00012 21.2 55.6 0.00066 18.8 15.8 4.3 2 2 0 3 3 3 2 ABC-2 family transporter protein AAA_16 PF13191.1 AEO57316.1 - 0.0013 18.7 1.1 0.081 12.9 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 AEO57316.1 - 0.0047 17.0 0.1 0.55 10.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 AEO57316.1 - 0.0051 17.1 0.2 0.21 11.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 AEO57316.1 - 0.0082 15.8 0.7 1 9.0 0.1 2.5 2 0 0 2 2 2 1 NACHT domain SMC_N PF02463.14 AEO57316.1 - 0.01 15.0 0.0 9.1 5.4 0.0 3.3 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain cobW PF02492.14 AEO57316.1 - 0.01 15.2 0.6 0.01 15.2 0.4 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 AEO57316.1 - 0.017 15.0 0.1 0.056 13.4 0.1 1.9 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 AEO57316.1 - 0.022 15.2 0.0 3.1 8.3 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein AAA_21 PF13304.1 AEO57316.1 - 0.033 14.1 0.1 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 AEO57316.1 - 0.037 13.9 0.0 11 6.0 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 AEO57316.1 - 0.046 13.1 0.3 6.6 6.1 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family RNA_helicase PF00910.17 AEO57316.1 - 0.13 12.4 0.1 23 5.2 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_10 PF12846.2 AEO57316.1 - 0.13 11.6 0.5 7.9 5.8 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain AAA PF00004.24 AEO57316.1 - 0.22 11.7 0.1 7.8 6.7 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 AEO57316.1 - 0.28 11.4 0.1 0.7 10.1 0.0 1.6 2 0 0 2 2 1 0 AAA domain UPF0079 PF02367.12 AEO57316.1 - 0.4 10.3 2.6 0.68 9.5 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF87 PF01935.12 AEO57316.1 - 6.6 6.4 4.6 32 4.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 WSC PF01822.14 AEO57317.1 - 7.8e-38 128.2 19.3 3e-19 68.7 2.7 2.1 2 0 0 2 2 2 2 WSC domain DUF4246 PF14033.1 AEO57318.1 - 8.2e-48 163.2 0.0 1.1e-47 162.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Zip PF02535.17 AEO57321.1 - 1.7e-41 142.2 12.3 2.6e-41 141.6 8.5 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter LEA_6 PF10714.4 AEO57321.1 - 0.56 10.0 3.4 1.4 8.7 2.3 1.7 1 0 0 1 1 1 0 Late embryogenesis abundant protein 18 Glyco_hydro_25 PF01183.15 AEO57322.1 - 9.1e-43 146.1 0.3 1.1e-42 145.9 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 Varsurf_PPLC PF03490.8 AEO57323.1 - 0.033 13.8 0.0 0.1 12.3 0.0 1.9 1 0 0 1 1 1 0 Variant-surface-glycoprotein phospholipase C PI-PLC-X PF00388.14 AEO57323.1 - 0.19 11.1 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain Glyco_hydro_17 PF00332.13 AEO57324.1 - 8.4e-07 28.3 1.3 5e-06 25.7 0.3 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 DUF1517 PF07466.6 AEO57324.1 - 0.59 9.0 3.9 0.89 8.4 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Zip PF02535.17 AEO57325.1 - 4.1e-50 170.5 11.6 5e-50 170.3 8.1 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter DUF3722 PF12519.3 AEO57326.1 - 2.3e-86 289.2 0.0 2.8e-86 288.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) Porin_3 PF01459.17 AEO57326.1 - 5e-05 22.7 0.0 0.0026 17.0 0.1 2.3 2 0 0 2 2 2 2 Eukaryotic porin Scytalone_dh PF02982.9 AEO57327.1 - 9.6e-89 295.0 0.9 1.1e-88 294.8 0.6 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 AEO57327.1 - 1.7e-07 31.1 0.4 2.3e-07 30.7 0.3 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF2293 PF10056.4 AEO57328.1 - 2e-33 114.1 1.1 4.2e-33 113.1 0.8 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) FMO-like PF00743.14 AEO57329.1 - 3.4e-38 131.1 0.0 1.5e-18 66.3 0.0 3.2 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 AEO57329.1 - 1.9e-21 77.0 0.0 5e-12 46.3 0.0 3.6 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AEO57329.1 - 7.5e-10 38.7 0.9 1.8e-08 34.2 0.0 3.4 4 0 0 4 4 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 AEO57329.1 - 2.3e-09 36.6 10.4 1.4e-07 30.7 3.2 3.4 3 1 0 4 4 4 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 AEO57329.1 - 1.9e-08 34.4 0.0 0.0076 16.1 0.2 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 AEO57329.1 - 3.4e-08 33.4 4.1 1.4e-05 24.9 0.2 3.9 4 0 0 4 4 4 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 AEO57329.1 - 7e-08 31.7 1.4 3.7e-06 26.0 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.19 AEO57329.1 - 3.7e-06 26.2 1.6 0.014 14.4 0.0 3.1 3 1 1 4 4 4 2 Flavin containing amine oxidoreductase Thi4 PF01946.12 AEO57329.1 - 1.4e-05 24.3 0.7 4.7e-05 22.5 0.6 1.7 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.2 AEO57329.1 - 3e-05 23.2 0.1 6.6e-05 22.1 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 AEO57329.1 - 4.2e-05 23.8 6.3 0.00079 19.7 0.5 3.7 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 AEO57329.1 - 0.00052 18.6 0.8 0.0071 14.8 1.3 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 AEO57329.1 - 0.00069 18.5 1.6 0.0017 17.2 1.1 1.7 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 AEO57329.1 - 0.0023 17.0 0.8 0.0088 15.1 0.5 1.8 2 0 0 2 2 2 1 FAD binding domain Shikimate_DH PF01488.15 AEO57329.1 - 0.0025 17.9 0.1 0.19 11.8 0.1 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 AEO57329.1 - 0.003 16.4 1.2 0.029 13.2 1.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_7 PF13241.1 AEO57329.1 - 0.018 15.3 0.1 1.7 8.9 0.0 3.2 4 0 0 4 4 4 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 AEO57329.1 - 0.023 14.3 1.8 0.046 13.3 1.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DJ-1_PfpI PF01965.19 AEO57329.1 - 0.11 11.9 0.0 9.4 5.6 0.0 2.4 2 0 0 2 2 2 0 DJ-1/PfpI family NAD_binding_2 PF03446.10 AEO57329.1 - 0.12 12.2 0.2 0.24 11.2 0.1 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Trp_halogenase PF04820.9 AEO57329.1 - 0.12 10.9 1.7 0.25 9.9 1.1 1.5 2 0 0 2 2 2 0 Tryptophan halogenase ApbA PF02558.11 AEO57329.1 - 0.15 11.4 0.9 0.4 10.1 0.5 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.1 AEO57329.1 - 0.81 9.6 3.5 0.87 9.5 0.9 2.2 3 0 0 3 3 3 0 NADH(P)-binding TauD PF02668.11 AEO57330.1 - 6.1e-51 173.5 0.1 8.2e-51 173.1 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Pepsin-I3 PF06394.8 AEO57330.1 - 0.16 11.6 0.7 4.3 7.0 0.1 2.6 2 1 1 3 3 3 0 Pepsin inhibitor-3-like repeated domain SNF2_N PF00176.18 AEO57331.1 - 5.7e-46 156.6 0.0 8.8e-46 156.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AEO57331.1 - 6.7e-08 32.2 0.0 2.7e-07 30.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_4 PF15227.1 AEO57331.1 - 5.2e-07 29.4 5.3 1.1e-06 28.4 3.7 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 AEO57331.1 - 5.6e-07 29.1 5.3 1.1e-06 28.2 3.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AEO57331.1 - 1.6e-05 24.8 7.0 3.3e-05 23.8 4.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AEO57331.1 - 5e-05 22.8 4.3 9.6e-05 21.9 3.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AEO57331.1 - 0.00021 21.0 5.0 0.00046 19.9 3.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 AEO57331.1 - 0.00023 20.7 3.3 0.00053 19.6 2.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 AEO57331.1 - 0.00071 19.2 6.1 0.0015 18.1 4.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 AEO57331.1 - 0.0016 17.9 1.8 0.0016 17.9 1.2 1.8 2 0 0 2 2 1 1 RING/Ubox like zinc-binding domain DUF3261 PF11659.3 AEO57331.1 - 0.069 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3261) DZR PF12773.2 AEO57331.1 - 1.1 9.1 9.0 11 5.8 6.3 2.1 1 1 0 1 1 1 0 Double zinc ribbon CorA PF01544.13 AEO57332.1 - 1.3e-28 99.8 1.9 2.8e-23 82.3 0.4 2.4 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein Carb_bind PF10645.4 AEO57333.1 - 1.4e-25 88.7 6.0 1.4e-25 88.7 4.2 1.8 2 0 0 2 2 2 1 Carbohydrate binding IGFL PF14653.1 AEO57333.1 - 0.84 9.7 3.6 2.7 8.0 2.5 2.0 1 1 0 1 1 1 0 Insulin growth factor-like family PAPS_reduct PF01507.14 AEO57334.1 - 3.5e-26 92.0 0.0 2.7e-18 66.4 0.0 2.3 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family RVT_1 PF00078.22 AEO57335.1 - 0.011 15.1 0.3 0.012 14.9 0.2 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3786 PF12654.2 AEO57335.1 - 0.043 13.0 0.2 0.053 12.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3786) Protoglobin PF11563.3 AEO57335.1 - 0.083 12.5 1.2 0.091 12.4 0.8 1.0 1 0 0 1 1 1 0 Protoglobin SNF2_N PF00176.18 AEO57336.1 - 2.5e-71 239.9 0.0 3.3e-71 239.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 AEO57336.1 - 1.2e-24 86.2 0.0 2.4e-24 85.2 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 AEO57336.1 - 8.4e-14 51.2 0.0 1.7e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 AEO57336.1 - 9.9e-07 28.6 9.4 2.1e-06 27.6 6.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AEO57336.1 - 0.00011 21.8 9.9 0.00021 20.8 6.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) UBA_4 PF14555.1 AEO57336.1 - 0.0038 16.7 0.0 0.014 14.9 0.0 2.0 2 0 0 2 2 2 1 UBA-like domain zf-C3HC4_3 PF13920.1 AEO57336.1 - 0.0042 16.7 7.6 0.0081 15.8 5.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AEO57336.1 - 0.0047 16.7 9.9 0.01 15.6 6.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 AEO57336.1 - 0.15 11.8 8.2 0.33 10.7 5.7 1.6 1 0 0 1 1 1 0 zinc-RING finger domain SQS_PSY PF00494.14 AEO57337.1 - 2.3e-57 194.3 0.0 2.9e-57 193.9 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase LDB19 PF13002.2 AEO57338.1 - 1.6e-35 122.3 1.1 2.1e-35 121.9 0.3 1.5 2 0 0 2 2 2 1 Arrestin_N terminal like Arrestin_N PF00339.24 AEO57338.1 - 2.9e-05 23.9 0.0 6.5e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain GTP_EFTU PF00009.22 AEO57339.1 - 4.1e-21 75.2 0.0 7.6e-21 74.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 AEO57339.1 - 1.6e-14 53.8 0.0 3.7e-14 52.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 AEO57339.1 - 1.5e-10 41.0 1.1 1.5e-09 37.8 0.7 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 AEO57339.1 - 0.00095 19.1 0.0 0.0024 17.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 AEO57339.1 - 0.0025 17.3 0.7 0.37 10.2 0.1 3.3 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 AEO57339.1 - 0.0025 18.2 0.1 0.03 14.8 0.1 2.6 2 1 0 2 2 2 1 Miro-like protein DUF258 PF03193.11 AEO57339.1 - 0.031 13.4 0.2 0.059 12.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 AEO57339.1 - 0.12 12.1 1.3 0.19 11.5 0.1 2.0 3 0 0 3 3 3 0 Dynamin family LSM PF01423.17 AEO57340.1 - 2.5e-17 62.1 0.2 3.2e-17 61.8 0.1 1.1 1 0 0 1 1 1 1 LSM domain PIG-L PF02585.12 AEO57341.1 - 5.4e-25 88.3 0.0 8.1e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Polysacc_deac_1 PF01522.16 AEO57343.1 - 1.4e-30 105.4 0.0 2e-30 104.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Abhydrolase_6 PF12697.2 AEO57344.1 - 2.5e-20 73.3 1.4 3e-20 73.0 1.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO57344.1 - 7.2e-06 25.7 0.0 3.4e-05 23.5 0.0 2.1 2 1 1 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AEO57344.1 - 4.4e-05 23.2 0.0 7.2e-05 22.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family MOSC PF03473.12 AEO57345.1 - 2.3e-13 49.7 0.0 4.1e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 AEO57345.1 - 1.6e-12 47.2 0.0 5.1e-12 45.5 0.0 1.8 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain Fungal_trans PF04082.13 AEO57346.1 - 5.2e-17 61.5 0.0 8.9e-17 60.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 AEO57346.1 - 1.1e-08 34.8 13.2 0.0007 19.7 2.7 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 AEO57346.1 - 1.4e-06 28.3 6.2 1.4e-06 28.3 4.3 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 AEO57346.1 - 6e-05 23.0 14.5 0.044 14.1 2.2 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 AEO57346.1 - 0.086 13.0 1.2 0.21 11.8 0.8 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 AEO57346.1 - 1.8 8.8 4.0 0.82 9.8 0.3 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding GntR PF00392.16 AEO57347.1 - 0.012 15.0 0.0 0.015 14.7 0.0 1.3 1 1 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_23 PF13384.1 AEO57347.1 - 0.02 14.5 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 Homeodomain-like domain HTH_Tnp_4 PF13613.1 AEO57347.1 - 0.073 12.6 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease RHH_4 PF13467.1 AEO57347.1 - 0.081 12.8 0.0 0.13 12.1 0.0 1.4 1 1 0 1 1 1 0 Ribbon-helix-helix domain FA_desaturase PF00487.19 AEO57349.1 - 2.6e-27 95.8 29.1 2.6e-27 95.8 20.2 1.5 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 AEO57349.1 - 3.4e-09 36.8 0.0 5.3e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) DUF2422 PF10337.4 AEO57350.1 - 7.9e-101 338.0 0.8 7.9e-101 338.0 0.5 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 AEO57350.1 - 2.1e-13 50.3 12.1 2.1e-13 50.3 8.4 2.7 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.3 AEO57350.1 - 0.058 12.0 8.5 0.12 10.9 5.9 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter AAA PF00004.24 AEO57352.1 - 5.1e-07 29.9 0.0 1.1e-06 28.8 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 AEO57352.1 - 4.5e-06 25.6 0.0 0.0029 16.3 0.0 3.2 3 0 0 3 3 3 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 AEO57352.1 - 8.1e-05 22.7 0.1 0.00026 21.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AEO57352.1 - 0.0021 18.8 0.0 0.0051 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 AEO57352.1 - 0.0066 16.1 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 AEO57352.1 - 0.013 15.4 0.0 0.034 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.1 AEO57352.1 - 0.042 13.7 0.0 0.089 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.4 AEO57352.1 - 0.084 11.7 0.0 0.17 10.8 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 RNA_helicase PF00910.17 AEO57352.1 - 0.086 13.0 0.0 0.52 10.4 0.0 2.3 3 0 0 3 3 3 0 RNA helicase PTCB-BRCT PF12738.2 AEO57355.1 - 1.4e-42 143.3 1.0 2.5e-20 72.0 0.0 4.4 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.21 AEO57355.1 - 9e-33 112.2 0.1 9.6e-13 48.1 0.0 4.6 4 1 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain NUDIX PF00293.23 AEO57355.1 - 4.7e-14 52.1 0.3 1e-13 51.0 0.2 1.5 1 0 0 1 1 1 1 NUDIX domain Asp PF00026.18 AEO57356.1 - 1.4e-58 198.6 0.0 1.9e-58 198.2 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 AEO57356.1 - 6.5e-11 42.4 0.5 3e-09 37.0 0.0 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 AEO57356.1 - 0.0054 16.2 0.0 0.096 12.2 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal DYW_deaminase PF14432.1 AEO57357.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 DYW family of nucleic acid deaminases Ribosomal_S19e PF01090.14 AEO57358.1 - 1.3e-58 196.4 0.7 1.5e-58 196.2 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Prim-Pol PF09250.6 AEO57358.1 - 0.028 14.3 0.1 0.045 13.7 0.1 1.4 1 1 0 1 1 1 0 Bifunctional DNA primase/polymerase, N-terminal Ricin_B_lectin PF00652.17 AEO57359.1 - 1.8e-16 60.2 0.2 1.7e-06 28.0 0.1 3.6 2 2 1 3 3 3 3 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 AEO57359.1 - 0.0017 18.6 0.0 0.54 10.6 0.0 3.4 2 2 2 4 4 4 1 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.9 AEO57359.1 - 0.096 12.0 1.4 4.9 6.5 0.0 3.8 3 2 1 4 4 4 0 Cytolethal distending toxin A/C family Fe-S_biosyn PF01521.15 AEO57360.1 - 1.6e-11 44.1 0.0 8.1e-06 25.7 0.0 2.2 2 0 0 2 2 2 2 Iron-sulphur cluster biosynthesis Ribosomal_L30_N PF08079.7 AEO57361.1 - 6.9e-27 93.2 18.3 1.2e-26 92.5 12.7 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 AEO57361.1 - 1.2e-20 72.8 2.3 1.9e-20 72.1 0.8 1.9 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Ribosomal_S11 PF00411.14 AEO57362.1 - 8.1e-41 138.6 0.4 1.1e-40 138.2 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 DUF2252 PF10009.4 AEO57362.1 - 0.028 13.3 0.0 0.033 13.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) eIF-3c_N PF05470.7 AEO57363.1 - 6.9e-175 582.5 19.0 6.9e-175 582.5 13.2 3.0 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 AEO57363.1 - 2.4e-14 53.5 0.1 1.5e-13 50.9 0.0 2.5 2 0 0 2 2 2 1 PCI domain PROCN PF08083.6 AEO57364.1 - 9.3e-221 732.4 10.3 1.6e-220 731.7 7.1 1.4 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 AEO57364.1 - 8.4e-126 417.9 1.8 1.4e-125 417.1 1.2 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 AEO57364.1 - 1.1e-93 310.8 1.0 2.8e-93 309.5 0.7 1.8 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 AEO57364.1 - 2.2e-77 257.9 2.2 2.2e-77 257.9 1.5 2.1 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 AEO57364.1 - 4.4e-67 223.8 0.1 9.4e-67 222.7 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.6 AEO57364.1 - 9.4e-45 151.3 0.2 2.8e-44 149.8 0.0 2.0 2 0 0 2 2 2 1 PROCT (NUC072) domain RRM_4 PF10598.4 AEO57364.1 - 3.5e-44 148.5 0.1 9e-44 147.2 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 Myb_DNA-bind_6 PF13921.1 AEO57365.1 - 5.2e-17 61.6 1.1 2.7e-11 43.3 0.1 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 AEO57365.1 - 9.3e-13 48.0 0.3 4.5e-05 23.4 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain DUF4085 PF13315.1 AEO57365.1 - 0.11 11.9 0.1 0.14 11.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) Totivirus_coat PF05518.6 AEO57365.1 - 0.4 8.4 4.3 0.52 8.0 3.0 1.2 1 0 0 1 1 1 0 Totivirus coat protein SNF2_N PF00176.18 AEO57367.1 - 1.2e-53 181.9 0.0 1.7e-53 181.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AEO57367.1 - 1.7e-16 59.8 0.0 4.2e-16 58.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 AEO57367.1 - 0.00015 20.7 0.0 0.00067 18.5 0.0 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Hemerythrin PF01814.18 AEO57368.1 - 9.2e-14 51.7 3.5 2.3e-13 50.4 2.4 1.6 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain Mpv17_PMP22 PF04117.7 AEO57369.1 - 1.4e-12 47.0 3.6 6e-12 45.0 2.2 2.0 2 0 0 2 2 2 1 Mpv17 / PMP22 family EAP30 PF04157.11 AEO57370.1 - 6.2e-67 225.0 0.0 7.2e-67 224.8 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family AAR2 PF05282.6 AEO57371.1 - 3.5e-42 144.6 0.0 5.1e-40 137.5 0.0 2.4 1 1 0 1 1 1 1 AAR2 protein DEAD PF00270.24 AEO57374.1 - 4.1e-46 156.5 0.0 1.6e-44 151.3 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO57374.1 - 1.4e-28 98.5 0.0 2.7e-28 97.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AEO57374.1 - 8.5e-05 22.4 0.0 0.00021 21.1 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 AEO57374.1 - 0.0073 14.7 0.0 0.36 9.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1253) GRP PF07172.6 AEO57374.1 - 0.0094 16.3 3.3 0.0094 16.3 2.3 3.5 2 1 1 3 3 3 1 Glycine rich protein family Helicase_C_2 PF13307.1 AEO57374.1 - 0.013 15.4 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain DUF2443 PF10398.4 AEO57374.1 - 0.029 14.1 0.3 0.074 12.8 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) Phos_pyr_kin PF08543.7 AEO57375.1 - 1.6e-82 276.3 0.6 2.9e-82 275.5 0.4 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 AEO57375.1 - 6e-49 166.6 0.2 9.5e-49 165.9 0.1 1.3 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 AEO57375.1 - 7.7e-08 31.8 0.2 1.2e-07 31.1 0.2 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HK PF02110.10 AEO57375.1 - 0.14 11.2 3.1 0.47 9.5 0.1 2.7 3 0 0 3 3 3 0 Hydroxyethylthiazole kinase family RICTOR_N PF14664.1 AEO57376.1 - 5.3e-114 380.6 1.6 1.2e-84 284.1 0.0 3.5 2 1 1 3 3 3 3 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 AEO57376.1 - 4.7e-91 303.8 0.7 4.5e-90 300.5 0.1 2.8 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 AEO57376.1 - 9.9e-43 144.7 0.1 5.6e-41 139.0 0.0 2.7 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 AEO57376.1 - 1.5e-28 98.4 0.5 1.1e-26 92.5 0.0 3.7 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 AEO57376.1 - 3.8e-14 52.1 4.8 3.8e-14 52.1 3.3 2.4 2 0 0 2 2 2 1 Hr1 repeat Proteasom_PSMB PF10508.4 AEO57376.1 - 4.1e-05 22.0 0.3 0.077 11.2 0.0 3.9 2 1 1 4 4 4 2 Proteasome non-ATPase 26S subunit OmpH PF03938.9 AEO57376.1 - 0.013 15.4 0.1 0.013 15.4 0.1 3.7 3 1 0 3 3 3 0 Outer membrane protein (OmpH-like) Uricase PF01014.13 AEO57377.1 - 3.8e-84 279.6 0.3 7e-46 155.7 0.2 2.0 2 0 0 2 2 2 2 Uricase HMA PF00403.21 AEO57378.1 - 4.9e-14 52.2 0.0 7.9e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.15 AEO57378.1 - 1.5e-13 51.0 0.0 2.4e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) TPR_11 PF13414.1 AEO57379.1 - 3.5e-21 74.6 11.6 5.8e-11 41.8 0.1 3.5 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 AEO57379.1 - 6.4e-17 60.3 12.3 5.1e-08 32.2 0.0 5.0 5 1 0 5 5 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 AEO57379.1 - 1.4e-15 55.8 6.0 1.3e-05 24.7 0.0 4.8 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.1 AEO57379.1 - 1e-12 47.8 1.5 2.4e-07 30.5 0.1 3.2 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 AEO57379.1 - 3.8e-12 45.0 3.4 2.8e-05 23.5 0.0 4.7 3 1 1 4 4 4 3 Tetratricopeptide repeat PB1 PF00564.19 AEO57379.1 - 9.2e-10 38.0 0.3 1.9e-09 37.0 0.2 1.5 1 0 0 1 1 1 1 PB1 domain TPR_6 PF13174.1 AEO57379.1 - 2.2e-08 34.0 3.0 0.068 13.6 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 AEO57379.1 - 8.2e-07 28.7 0.2 0.019 14.8 0.0 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 AEO57379.1 - 1.7e-06 27.7 3.0 0.0027 17.7 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 AEO57379.1 - 2.1e-06 28.2 1.7 0.0014 19.2 0.4 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 AEO57379.1 - 5.4e-06 25.7 2.3 0.00041 19.9 0.0 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 AEO57379.1 - 0.00012 22.3 1.2 0.075 13.6 0.0 3.8 2 1 2 4 4 4 1 Tetratricopeptide repeat Ribosomal_S21 PF01165.15 AEO57379.1 - 0.011 15.1 0.7 0.22 11.0 0.0 3.2 4 0 0 4 4 3 0 Ribosomal protein S21 TPR_19 PF14559.1 AEO57379.1 - 0.02 15.2 0.3 0.14 12.4 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 AEO57379.1 - 0.02 15.0 3.7 0.029 14.4 0.1 2.5 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 AEO57379.1 - 0.056 13.3 1.2 0.31 10.9 0.0 2.9 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain DUF3808 PF10300.4 AEO57379.1 - 0.17 10.4 0.4 0.33 9.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3808) DUF853 PF05872.7 AEO57380.1 - 0.012 14.0 5.1 0.016 13.5 3.5 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Band_3_cyto PF07565.8 AEO57380.1 - 0.26 10.7 4.9 0.34 10.3 3.4 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain eIF-3_zeta PF05091.7 AEO57380.1 - 0.27 9.7 7.8 0.32 9.5 5.4 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4407 PF14362.1 AEO57380.1 - 0.55 9.1 5.4 0.74 8.7 3.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FimP PF09766.4 AEO57380.1 - 0.75 8.7 16.0 1.1 8.2 11.1 1.1 1 0 0 1 1 1 0 Fms-interacting protein RR_TM4-6 PF06459.7 AEO57380.1 - 2.1 8.1 6.6 3.2 7.5 4.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Spt20 PF12090.3 AEO57380.1 - 2.1 7.6 11.5 0.17 11.1 4.8 1.7 2 0 0 2 2 2 0 Spt20 family Macoilin PF09726.4 AEO57380.1 - 2.7 6.1 11.0 2.7 6.1 7.6 1.1 1 0 0 1 1 1 0 Transmembrane protein BRF1 PF07741.8 AEO57380.1 - 2.7 8.2 7.8 0.5 10.6 2.0 2.2 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Zip PF02535.17 AEO57380.1 - 4 6.3 4.4 4.9 6.0 3.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter RED_N PF07808.8 AEO57380.1 - 4.4 6.4 14.0 8.2 5.5 9.7 1.4 1 0 0 1 1 1 0 RED-like protein N-terminal region DUF4175 PF13779.1 AEO57380.1 - 7.3 4.1 30.4 12 3.4 21.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DNA_Packaging PF11053.3 AEO57381.1 - 0.027 14.0 0.1 0.031 13.9 0.1 1.1 1 0 0 1 1 1 0 Terminase DNA packaging enzyme Hep_59 PF07052.6 AEO57381.1 - 0.086 13.2 0.8 0.14 12.5 0.2 1.6 2 0 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 Ribosomal_L34e PF01199.13 AEO57382.1 - 8.1e-38 128.5 3.0 1.1e-37 128.1 2.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e FhuF_C PF11575.3 AEO57382.1 - 1 9.0 6.1 2.5 7.8 0.2 2.7 3 0 0 3 3 3 0 FhuF 2Fe-2S C-terminal domain DUF498 PF04430.9 AEO57383.1 - 9.7e-28 95.9 0.0 7.8e-27 93.0 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) DUF4349 PF14257.1 AEO57383.1 - 0.051 12.7 0.3 0.095 11.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Macoilin PF09726.4 AEO57383.1 - 0.69 8.1 2.4 0.95 7.6 1.7 1.2 1 0 0 1 1 1 0 Transmembrane protein SR-25 PF10500.4 AEO57383.1 - 1.4 8.2 29.9 0.45 9.9 4.5 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein CMAS PF02353.15 AEO57384.1 - 1.4e-64 217.7 0.1 1.8e-64 217.4 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 AEO57384.1 - 1.4e-12 47.6 0.0 5.2e-12 45.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO57384.1 - 5.3e-09 36.4 0.0 1e-08 35.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO57384.1 - 5.7e-05 23.6 0.0 0.00018 22.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO57384.1 - 0.00055 20.2 0.0 0.0017 18.7 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO57384.1 - 0.0011 18.5 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO57384.1 - 0.0025 18.2 0.0 0.0051 17.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 AEO57384.1 - 0.014 14.9 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.8 AEO57384.1 - 0.015 14.6 0.0 0.036 13.3 0.0 1.5 2 0 0 2 2 2 0 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 AEO57384.1 - 0.026 14.5 0.0 0.056 13.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 AEO57384.1 - 0.064 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.1 AEO57384.1 - 0.075 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain HNH_2 PF13391.1 AEO57385.1 - 1e-11 44.3 0.0 2.1e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease G-patch_2 PF12656.2 AEO57386.1 - 9.3e-15 54.2 0.9 3.7e-14 52.3 0.1 2.5 2 0 0 2 2 2 1 DExH-box splicing factor binding site PRP38_assoc PF12871.2 AEO57386.1 - 0.016 15.7 14.0 0.016 15.7 9.7 3.8 2 1 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term HSA PF07529.8 AEO57387.1 - 7.2e-21 73.7 0.6 7.2e-21 73.7 0.4 5.4 4 1 1 5 5 5 2 HSA Myb_DNA-bind_6 PF13921.1 AEO57387.1 - 1.2e-13 50.9 1.3 1.8e-13 50.3 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 AEO57387.1 - 0.00038 20.4 0.1 0.0012 18.8 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Otopetrin PF03189.8 AEO57387.1 - 4 6.3 5.7 6.8 5.5 3.9 1.5 1 0 0 1 1 1 0 Otopetrin WD40 PF00400.27 AEO57388.1 - 1.2e-15 56.7 0.1 0.0011 18.7 0.0 5.5 6 0 0 6 6 6 4 WD domain, G-beta repeat INSIG PF07281.7 AEO57389.1 - 9.5e-53 178.4 0.0 2e-52 177.3 0.0 1.5 1 1 0 1 1 1 1 Insulin-induced protein (INSIG) CDK2AP PF09806.4 AEO57389.1 - 0.006 16.8 1.6 0.31 11.2 0.0 2.3 2 0 0 2 2 2 1 Cyclin-dependent kinase 2-associated protein Pex14_N PF04695.8 AEO57389.1 - 0.016 15.2 2.2 0.042 13.8 0.3 2.4 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region bHLH-MYC_N PF14215.1 AEO57389.1 - 0.019 15.1 0.0 0.03 14.5 0.0 1.3 1 0 0 1 1 1 0 bHLH-MYC and R2R3-MYB transcription factors N-terminal efThoc1 PF11957.3 AEO57390.1 - 1e-159 532.1 1.0 1.3e-159 531.8 0.7 1.1 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Guanylate_kin PF00625.16 AEO57390.1 - 3.8e-16 59.0 0.2 8.7e-16 57.8 0.0 1.7 2 0 0 2 2 2 1 Guanylate kinase FolB PF02152.13 AEO57390.1 - 0.061 13.4 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Dihydroneopterin aldolase AAA_11 PF13086.1 AEO57391.1 - 5.2e-22 78.5 0.0 1.3e-21 77.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_12 PF13087.1 AEO57391.1 - 1.8e-13 50.3 0.0 3.3e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AEO57391.1 - 3.5e-09 36.2 0.0 5.4e-08 32.4 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 AEO57391.1 - 4.2e-07 29.7 0.0 0.0033 17.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 AEO57391.1 - 6.8e-05 22.7 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_25 PF13481.1 AEO57391.1 - 0.00078 18.8 0.0 0.0017 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 AEO57391.1 - 0.0016 18.6 0.0 0.0054 16.9 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AEO57391.1 - 0.0064 16.6 0.0 0.022 14.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 AEO57391.1 - 0.0099 14.9 0.1 0.059 12.4 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin DEAD PF00270.24 AEO57391.1 - 0.011 15.2 0.0 0.033 13.6 0.0 1.8 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_16 PF13191.1 AEO57391.1 - 0.016 15.2 0.7 0.068 13.1 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain DnaB_C PF03796.10 AEO57391.1 - 0.036 12.9 0.0 0.065 12.1 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain DUF2075 PF09848.4 AEO57391.1 - 0.037 13.0 0.0 0.06 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Arch_ATPase PF01637.13 AEO57391.1 - 0.04 13.6 0.0 0.074 12.7 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA_17 PF13207.1 AEO57391.1 - 0.041 14.7 0.0 0.86 10.4 0.0 3.1 3 0 0 3 3 2 0 AAA domain NB-ARC PF00931.17 AEO57391.1 - 0.075 11.8 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RecA PF00154.16 AEO57391.1 - 0.1 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 recA bacterial DNA recombination protein RNA_helicase PF00910.17 AEO57391.1 - 0.12 12.5 0.0 0.35 11.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.12 AEO57391.1 - 0.18 10.6 0.0 0.29 9.9 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PIF1 PF05970.9 AEO57391.1 - 0.26 10.1 0.0 18 4.1 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase MIF4G PF02854.14 AEO57392.1 - 3.1e-52 177.0 0.0 5.3e-52 176.2 0.0 1.4 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 AEO57392.1 - 2.1e-20 72.3 0.1 6.9e-20 70.7 0.1 2.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 Eno-Rase_FAD_bd PF07055.7 AEO57392.1 - 0.066 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Enoyl reductase FAD binding domain DNA_pol_B PF00136.16 AEO57393.1 - 1.1e-108 364.0 0.1 1.8e-108 363.2 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 AEO57393.1 - 4.1e-66 221.9 0.0 8.7e-66 220.8 0.0 1.6 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 AEO57393.1 - 6.4e-39 133.6 0.0 1.9e-38 132.1 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 AEO57393.1 - 6.4e-23 80.3 8.7 6.4e-23 80.3 6.0 3.0 3 0 0 3 3 3 1 DNA polymerase alpha subunit p180 N terminal PPR_2 PF13041.1 AEO57394.1 - 7.1e-26 89.9 2.2 1.2e-15 57.2 0.1 5.3 4 1 1 5 5 5 3 PPR repeat family PPR_3 PF13812.1 AEO57394.1 - 1.7e-12 46.5 4.9 0.002 18.2 0.0 6.3 6 0 0 6 6 6 3 Pentatricopeptide repeat domain PPR PF01535.15 AEO57394.1 - 1.7e-06 27.5 3.5 0.0003 20.5 0.1 5.0 6 0 0 6 6 6 1 PPR repeat PPR_1 PF12854.2 AEO57394.1 - 1.8e-06 27.3 3.1 0.0006 19.2 0.0 4.3 5 0 0 5 5 5 2 PPR repeat LIM_bind PF01803.11 AEO57394.1 - 0.01 15.0 1.1 0.021 13.9 0.8 1.5 1 0 0 1 1 1 1 LIM-domain binding protein Suf PF05843.9 AEO57394.1 - 0.014 15.1 3.6 0.042 13.5 2.5 1.8 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RRM_1 PF00076.17 AEO57397.1 - 1.3e-05 24.7 0.0 2.3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO57397.1 - 0.0021 17.8 0.0 0.004 16.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO57397.1 - 0.0069 16.3 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Btz PF09405.5 AEO57397.1 - 0.024 14.6 0.4 0.024 14.6 0.2 1.7 2 0 0 2 2 2 0 CASC3/Barentsz eIF4AIII binding Pkinase PF00069.20 AEO57398.1 - 7.4e-53 179.3 0.0 1.5e-52 178.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO57398.1 - 1.1e-23 83.6 0.5 1.8e-23 82.9 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 AEO57398.1 - 0.00043 20.0 1.6 0.00052 19.8 0.1 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 AEO57398.1 - 0.0029 16.9 0.2 0.0098 15.2 0.2 1.6 1 1 0 1 1 1 1 RIO1 family DUF4430 PF14478.1 AEO57398.1 - 0.086 12.8 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4430) RRM_1 PF00076.17 AEO57399.1 - 6.6e-61 201.8 0.0 1.9e-21 75.4 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO57399.1 - 3e-43 145.6 0.0 8.9e-15 54.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO57399.1 - 2.6e-31 107.2 0.0 2e-10 40.3 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 AEO57399.1 - 7.6e-06 25.5 0.1 0.032 13.9 0.0 3.4 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.5 AEO57399.1 - 0.0034 17.2 0.0 2.8 7.9 0.0 2.4 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) Phi_1 PF04674.7 AEO57399.1 - 0.035 13.2 3.7 0.061 12.4 2.6 1.3 1 0 0 1 1 1 0 Phosphate-induced protein 1 conserved region RRM_3 PF08777.6 AEO57399.1 - 0.079 12.8 0.0 2.5 7.9 0.0 2.4 2 0 0 2 2 2 0 RNA binding motif Limkain-b1 PF11608.3 AEO57399.1 - 0.18 11.5 0.1 9.2 6.0 0.0 2.9 3 0 0 3 3 3 0 Limkain b1 Med2 PF11214.3 AEO57400.1 - 0.0063 16.5 0.0 0.0094 15.9 0.0 1.2 1 0 0 1 1 1 1 Mediator complex subunit 2 Cellulase PF00150.13 AEO57401.1 - 1.8e-16 60.2 0.0 4.1e-16 58.9 0.0 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PH PF00169.24 AEO57402.1 - 5.9e-25 87.4 1.3 7.2e-16 58.2 0.1 2.2 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 AEO57402.1 - 1.4e-10 41.4 5.5 6.4e-06 26.3 0.1 3.6 2 2 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.1 AEO57402.1 - 5e-10 39.5 1.5 3e-06 27.3 0.2 3.6 2 2 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.1 AEO57402.1 - 0.0011 18.8 0.3 0.014 15.3 0.1 2.3 2 0 0 2 2 2 1 PH domain PH_8 PF15409.1 AEO57402.1 - 0.0092 16.0 0.1 0.021 14.9 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain APH PF01636.18 AEO57403.1 - 1.3e-09 38.1 0.0 1.8e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 AEO57403.1 - 8.5e-05 21.8 0.0 0.00026 20.2 0.0 1.7 1 1 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 AEO57403.1 - 0.0064 16.0 0.0 0.018 14.6 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 AEO57403.1 - 0.068 12.1 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 Fructosamine kinase DUF1679 PF07914.6 AEO57403.1 - 0.082 11.5 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) DUF2392 PF10288.4 AEO57404.1 - 7.2e-14 52.0 0.0 1.8e-09 37.8 0.0 3.0 2 1 0 2 2 2 2 Protein of unknown function (DUF2392) ATP_bind_3 PF01171.15 AEO57404.1 - 0.011 15.2 0.3 0.86 9.0 0.0 2.2 2 0 0 2 2 2 0 PP-loop family OAD_gamma PF04277.8 AEO57404.1 - 4.9 7.6 6.6 5.8 7.3 3.4 1.9 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Mito_fiss_reg PF05308.6 AEO57404.1 - 6.5 6.0 10.4 4.1 6.7 5.7 1.6 1 1 0 1 1 1 0 Mitochondrial fission regulator Mito_carr PF00153.22 AEO57405.1 - 3.5e-60 199.7 1.4 1.2e-20 72.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein HET PF06985.6 AEO57406.1 - 1.4e-17 64.1 0.0 2.5e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) WD40 PF00400.27 AEO57407.1 - 3.8e-18 64.5 0.9 8e-09 35.0 0.0 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 AEO57407.1 - 0.017 13.2 0.0 0.042 11.9 0.0 1.7 2 0 0 2 2 2 0 Nucleoporin Nup120/160 SRP9-21 PF05486.7 AEO57408.1 - 6.9e-28 96.2 0.1 9.2e-28 95.8 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) DUF3738 PF12543.3 AEO57408.1 - 0.061 12.8 1.0 0.075 12.6 0.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3738) Ribonuc_red_sm PF00268.16 AEO57409.1 - 3.4e-121 403.5 1.4 4.1e-121 403.3 1.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF4112 PF13430.1 AEO57410.1 - 2.4e-31 107.8 0.1 2.9e-31 107.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) NUDIX PF00293.23 AEO57411.1 - 1.6e-14 53.6 0.0 3.2e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DCP2 PF05026.8 AEO57411.1 - 1.1e-05 25.2 0.1 2.2e-05 24.2 0.1 1.6 1 0 0 1 1 1 1 Dcp2, box A domain RRM_6 PF14259.1 AEO57412.1 - 0.0058 16.5 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CAP_N PF01213.14 AEO57413.1 - 0.73 9.0 3.6 1.1 8.5 2.5 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RAP1 PF07218.6 AEO57413.1 - 2.4 6.1 4.8 2.9 5.8 3.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pkinase PF00069.20 AEO57414.1 - 1e-46 159.2 0.0 1.3e-46 158.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO57414.1 - 1.2e-18 67.1 0.0 3.9e-18 65.4 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO57414.1 - 0.001 18.1 0.0 0.0015 17.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AEO57414.1 - 0.0063 16.2 0.0 0.032 13.9 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 AEO57414.1 - 0.077 12.0 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1900 PF08954.6 AEO57415.1 - 3e-49 166.0 0.0 1.4e-48 163.8 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 AEO57415.1 - 8.1e-35 118.2 0.0 1.7e-34 117.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 AEO57415.1 - 1.7e-24 84.7 4.8 3.2e-07 29.9 0.1 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 AEO57415.1 - 0.013 13.6 0.3 0.052 11.6 0.1 1.8 1 1 1 2 2 2 0 Nucleoporin Nup120/160 eIF2A PF08662.6 AEO57415.1 - 0.1 12.3 0.0 0.36 10.5 0.0 1.8 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A SlyX PF04102.7 AEO57415.1 - 0.14 12.5 7.7 0.64 10.4 3.4 2.5 2 0 0 2 2 2 0 SlyX Glyco_transf_22 PF03901.12 AEO57416.1 - 3.6e-77 260.1 19.1 4.2e-77 259.9 13.2 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family LigD_N PF13298.1 AEO57416.1 - 0.013 15.5 0.1 0.026 14.6 0.1 1.4 1 0 0 1 1 1 0 DNA polymerase Ligase (LigD) Sensor_TM1 PF13755.1 AEO57416.1 - 0.053 13.0 1.0 0.097 12.1 0.1 1.9 2 0 0 2 2 2 0 Sensor N-terminal transmembrane domain Aminotran_3 PF00202.16 AEO57417.1 - 2.2e-105 352.2 0.0 2.7e-105 351.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 AEO57417.1 - 2.8e-05 23.4 0.0 5e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DUF3543 PF12063.3 AEO57418.1 - 7.4e-97 323.2 0.9 7.4e-97 323.2 0.7 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 AEO57418.1 - 3.9e-62 209.7 0.2 7.9e-62 208.7 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO57418.1 - 6.9e-40 136.7 0.0 1.6e-39 135.5 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AEO57418.1 - 0.2 11.3 2.8 1.3 8.7 0.0 2.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family DUF1423 PF07227.6 AEO57418.1 - 0.39 9.3 5.3 0.65 8.5 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) FLO_LFY PF01698.11 AEO57418.1 - 0.6 8.9 6.6 1.1 8.0 4.6 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein Suf PF05843.9 AEO57418.1 - 7.5 6.1 10.6 0.15 11.7 2.5 1.7 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Zeta_toxin PF06414.7 AEO57419.1 - 1.2e-31 109.3 0.0 3.6e-25 88.2 0.0 2.2 2 0 0 2 2 2 2 Zeta toxin AAA_33 PF13671.1 AEO57419.1 - 7.4e-05 22.6 1.4 0.0006 19.7 1.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AEO57419.1 - 0.011 15.7 2.3 0.011 15.6 0.4 2.0 2 1 0 2 2 2 0 AAA ATPase domain NACHT PF05729.7 AEO57419.1 - 0.016 14.8 0.0 0.037 13.6 0.1 1.6 2 0 0 2 2 2 0 NACHT domain TrwB_AAD_bind PF10412.4 AEO57419.1 - 0.035 12.7 0.1 0.059 11.9 0.1 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.1 AEO57419.1 - 0.038 14.1 0.0 0.059 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 AEO57419.1 - 0.052 13.3 0.0 0.096 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 AEO57419.1 - 0.086 12.3 0.0 0.43 10.0 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family IstB_IS21 PF01695.12 AEO57419.1 - 0.14 11.5 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein UPF0079 PF02367.12 AEO57419.1 - 0.15 11.6 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_25 PF13481.1 AEO57419.1 - 0.54 9.6 4.5 2.7 7.3 0.5 2.6 2 1 0 2 2 2 0 AAA domain MFS_1 PF07690.11 AEO57420.1 - 1e-33 116.5 22.7 1.6e-33 115.9 15.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily RhoGAP PF00620.22 AEO57421.1 - 2.5e-38 131.0 0.0 4.3e-38 130.3 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain SH3_3 PF08239.6 AEO57422.1 - 0.002 18.3 0.0 0.0053 16.9 0.0 1.8 1 0 0 1 1 1 1 Bacterial SH3 domain Amidase_5 PF05382.8 AEO57422.1 - 0.0047 16.5 3.4 0.092 12.3 2.3 2.3 1 1 0 1 1 1 1 Bacteriophage peptidoglycan hydrolase DUF3328 PF11807.3 AEO57423.1 - 1.7e-32 112.8 0.1 2.1e-32 112.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) zf-Tim10_DDP PF02953.10 AEO57424.1 - 7.8e-20 69.9 0.7 1.1e-19 69.4 0.5 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 AEO57424.1 - 0.028 13.8 1.3 0.22 10.9 0.7 1.9 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) HATPase_c_5 PF14501.1 AEO57424.1 - 0.037 13.7 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 GHKL domain Thionin PF00321.12 AEO57424.1 - 0.079 13.1 0.9 0.12 12.6 0.6 1.3 1 0 0 1 1 1 0 Plant thionin DUF3811 PF11656.3 AEO57424.1 - 0.12 12.4 0.5 0.17 11.9 0.2 1.4 1 1 0 1 1 1 0 YjbD family (DUF3811) Nup188 PF10487.4 AEO57425.1 - 1.2e-26 93.0 0.0 1.1e-22 79.8 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 RTC_insert PF05189.8 AEO57425.1 - 0.022 14.7 0.0 0.086 12.8 0.0 2.0 1 0 0 1 1 1 0 RNA 3'-terminal phosphate cyclase (RTC), insert domain IGPS PF00218.16 AEO57426.1 - 1.5e-97 325.6 0.0 2.4e-97 324.9 0.0 1.3 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase GATase PF00117.23 AEO57426.1 - 2.2e-51 174.0 0.0 3.8e-51 173.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I PRAI PF00697.17 AEO57426.1 - 2.9e-49 167.3 0.0 6.5e-45 153.1 0.0 2.5 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Peptidase_C26 PF07722.8 AEO57426.1 - 4.2e-05 23.0 0.0 9.5e-05 21.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.14 AEO57426.1 - 0.019 14.5 0.2 0.087 12.3 0.0 2.2 3 0 0 3 3 3 0 Quinolinate phosphoribosyl transferase, C-terminal domain PTCB-BRCT PF12738.2 AEO57427.1 - 0.064 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 twin BRCT domain BRCT PF00533.21 AEO57427.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Use1 PF09753.4 AEO57428.1 - 4e-06 26.4 0.0 2.4e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Membrane fusion protein Use1 DUF3347 PF11827.3 AEO57428.1 - 0.033 14.1 3.1 3.6 7.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) DUF605 PF04652.11 AEO57428.1 - 0.037 13.4 23.6 0.046 13.1 16.4 1.2 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 AEO57428.1 - 0.092 10.9 9.9 0.11 10.7 6.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SMN PF06003.7 AEO57428.1 - 0.29 10.2 15.5 0.47 9.5 10.7 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) IncA PF04156.9 AEO57428.1 - 0.37 10.3 9.8 2.9 7.4 0.0 2.4 2 0 0 2 2 2 0 IncA protein Tir_receptor_C PF07489.6 AEO57428.1 - 0.69 9.6 7.8 1.1 8.9 5.4 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Synaptobrevin PF00957.16 AEO57428.1 - 9 5.9 6.8 0.52 9.9 0.2 2.2 3 0 0 3 3 3 0 Synaptobrevin Methyltransf_28 PF02636.12 AEO57429.1 - 2.7e-80 269.4 0.0 3.5e-80 269.0 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Lung_7-TM_R PF06814.8 AEO57430.1 - 6.4e-65 219.0 22.6 7.6e-64 215.4 15.7 2.0 1 1 0 1 1 1 1 Lung seven transmembrane receptor DUF4492 PF14899.1 AEO57430.1 - 0.018 14.5 0.9 0.054 12.9 0.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4492) PrgI PF12666.2 AEO57430.1 - 0.53 10.4 19.3 0.077 13.1 1.9 3.6 1 1 1 3 3 3 0 PrgI family protein DUF1673 PF07895.6 AEO57430.1 - 2 7.9 9.6 0.23 10.9 3.3 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1673) Pro_isomerase PF00160.16 AEO57431.1 - 2.1e-45 154.7 0.0 3.8e-45 153.8 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.10 AEO57431.1 - 9.6e-06 25.4 0.0 4.6e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 U-box domain Rtf2 PF04641.7 AEO57431.1 - 0.00027 20.2 0.2 0.002 17.3 0.0 2.3 2 1 0 2 2 2 1 Rtf2 RING-finger MSA-2c PF12238.3 AEO57431.1 - 0.5 9.9 5.0 0.23 11.1 1.1 2.0 2 0 0 2 2 2 0 Merozoite surface antigen 2c Fungal_trans_2 PF11951.3 AEO57432.1 - 2.6e-08 32.8 0.7 1.9e-05 23.4 0.0 2.6 3 0 0 3 3 3 2 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO57432.1 - 6.7e-07 29.1 12.8 1.9e-06 27.6 8.8 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ComFB PF10719.4 AEO57432.1 - 0.13 11.9 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 Late competence development protein ComFB KTI12 PF08433.5 AEO57433.1 - 7.7e-61 205.6 0.0 5.2e-60 202.9 0.0 1.9 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 AEO57433.1 - 0.00019 21.3 0.0 0.00045 20.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AEO57433.1 - 0.0062 17.3 0.4 0.022 15.5 0.3 2.3 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 AEO57433.1 - 0.021 14.7 0.0 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 AEO57433.1 - 0.024 14.9 0.0 0.075 13.3 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 AEO57433.1 - 0.093 12.7 0.1 0.31 11.0 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain 6PF2K PF01591.13 AEO57433.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Sec63 PF02889.11 AEO57434.1 - 8.1e-44 150.1 0.0 2.4e-43 148.5 0.0 1.7 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 AEO57434.1 - 1.3e-18 66.4 1.5 3e-18 65.3 1.0 1.6 1 0 0 1 1 1 1 DnaJ domain DUF4131 PF13567.1 AEO57434.1 - 0.0029 17.0 0.0 0.0058 16.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) UPF0104 PF03706.8 AEO57434.1 - 0.027 13.7 0.1 0.061 12.6 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) DUF4229 PF14012.1 AEO57434.1 - 0.067 13.1 1.1 0.32 10.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) Ni_hydr_CYTB PF01292.15 AEO57434.1 - 0.076 12.3 0.1 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 MFS_1 PF07690.11 AEO57434.1 - 0.077 11.6 0.1 0.14 10.8 0.1 1.3 1 0 0 1 1 1 0 Major Facilitator Superfamily EF-hand_6 PF13405.1 AEO57435.1 - 2e-14 52.0 0.0 4.2e-06 26.1 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 AEO57435.1 - 1.1e-11 43.1 0.8 0.00012 21.1 0.1 2.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 AEO57435.1 - 6.1e-10 39.0 0.0 0.00058 19.9 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 AEO57435.1 - 4.3e-09 35.2 3.1 0.00016 20.8 0.4 2.3 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 AEO57435.1 - 8e-05 22.1 0.0 0.34 10.5 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.1 AEO57435.1 - 0.00074 19.3 0.0 0.45 10.4 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain ORC6 PF05460.8 AEO57435.1 - 0.0074 15.4 0.7 0.011 14.8 0.5 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Afi1 PF07792.7 AEO57436.1 - 4.1e-65 218.2 0.0 8.1e-65 217.2 0.0 1.5 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 AEO57436.1 - 3.6e-38 129.7 0.0 7e-38 128.8 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 AEO57436.1 - 3.5e-08 32.3 0.1 0.019 13.4 0.0 3.9 3 1 1 4 4 4 2 Transport protein Avl9 DUF2347 PF09804.4 AEO57436.1 - 0.016 14.4 0.0 0.096 11.9 0.0 2.2 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) Nop14 PF04147.7 AEO57436.1 - 1.9 6.3 13.2 3.1 5.5 9.2 1.2 1 0 0 1 1 1 0 Nop14-like family Esterase PF00756.15 AEO57437.1 - 6.7e-50 169.8 0.0 8e-50 169.6 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 AEO57437.1 - 1.5e-07 31.2 0.0 1.9e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AEO57437.1 - 1.9e-05 24.6 0.1 2.9e-05 24.0 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 AEO57437.1 - 0.00011 21.5 0.0 0.00016 20.9 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.4 AEO57437.1 - 0.0011 18.2 0.2 0.0031 16.7 0.1 1.7 1 1 0 1 1 1 1 Esterase PHB depolymerase DLH PF01738.13 AEO57437.1 - 0.13 11.5 0.9 0.42 9.8 0.6 1.7 1 1 0 1 1 1 0 Dienelactone hydrolase family GARS_A PF01071.14 AEO57440.1 - 4e-82 274.5 0.0 5.6e-82 274.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 AEO57440.1 - 4.4e-35 120.1 0.0 1.3e-34 118.6 0.0 1.9 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 AEO57440.1 - 8.9e-33 113.4 0.0 1.7e-32 112.5 0.0 1.5 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 AEO57440.1 - 7e-28 96.6 0.0 1.7e-27 95.4 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 AEO57440.1 - 1.5e-14 53.9 3.9 3e-14 53.0 1.2 2.7 3 0 0 3 3 2 1 AIR synthase related protein, N-terminal domain ATPgrasp_Ter PF15632.1 AEO57440.1 - 2.2e-09 36.5 0.0 7.1e-09 34.8 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 AEO57440.1 - 2.8e-09 36.9 0.0 7.4e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 AEO57440.1 - 2.7e-05 23.5 0.0 5.2e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.17 AEO57440.1 - 3.9e-05 23.0 0.0 7e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 AEO57440.1 - 0.0095 15.8 0.2 0.027 14.3 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_2 PF08442.5 AEO57440.1 - 0.08 12.3 0.1 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain RimK PF08443.6 AEO57440.1 - 0.13 11.7 0.2 0.37 10.2 0.0 1.8 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Acyltransferase PF01553.16 AEO57441.1 - 1.5e-32 111.8 0.0 2.3e-32 111.2 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DUF4281 PF14108.1 AEO57441.1 - 0.066 13.3 2.4 0.11 12.6 1.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4281) ABC2_membrane_3 PF12698.2 AEO57441.1 - 0.52 9.2 8.3 0.86 8.5 5.7 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2347 PF09804.4 AEO57442.1 - 2e-105 352.1 0.0 2.9e-105 351.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 AEO57442.1 - 1.4e-50 171.8 0.7 5.3e-50 169.9 0.5 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4484) SPA PF08616.5 AEO57442.1 - 9e-06 25.3 0.0 2.6e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 Stabilization of polarity axis Rrn6 PF10214.4 AEO57443.1 - 0.24 9.4 3.2 0.36 8.8 2.2 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor WD40 PF00400.27 AEO57444.1 - 1.9e-67 220.9 15.1 1.2e-10 40.8 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 AEO57444.1 - 1.5e-27 95.5 10.8 2.3e-27 94.9 7.5 1.3 1 0 0 1 1 1 1 Tup N-terminal Nup160 PF11715.3 AEO57444.1 - 5.5e-05 21.5 1.6 0.24 9.4 0.1 3.7 1 1 3 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 AEO57444.1 - 0.0048 15.6 0.1 1.1 7.9 0.0 3.3 1 1 3 4 4 4 1 Nup133 N terminal like Nbas_N PF15492.1 AEO57444.1 - 0.017 14.2 0.1 10 5.1 0.0 3.3 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 AEO57444.1 - 0.072 11.3 0.2 1.4 7.1 0.1 2.4 1 1 1 2 2 2 0 Cytochrome D1 heme domain LXG PF04740.7 AEO57444.1 - 0.083 12.6 2.8 0.12 12.1 1.9 1.1 1 0 0 1 1 1 0 LXG domain of WXG superfamily Myosin_tail_1 PF01576.14 AEO57444.1 - 0.092 10.4 4.3 0.13 9.9 3.0 1.1 1 0 0 1 1 1 0 Myosin tail IKI3 PF04762.7 AEO57444.1 - 0.18 9.5 0.0 0.26 9.0 0.0 1.2 1 0 0 1 1 1 0 IKI3 family DUF2015 PF09435.5 AEO57445.1 - 7.6e-50 167.9 0.0 8.5e-50 167.8 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Ribosomal_L28e PF01778.12 AEO57446.1 - 1.4e-38 131.9 0.6 1.8e-38 131.5 0.4 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family Ldh_1_C PF02866.13 AEO57447.1 - 8.6e-44 149.3 0.0 1.2e-43 148.7 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 AEO57447.1 - 1.5e-43 148.0 0.1 2.1e-43 147.5 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 AEO57447.1 - 0.00051 18.8 0.0 0.0013 17.4 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.11 AEO57447.1 - 0.022 14.0 0.1 1.7 7.9 0.0 2.2 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase TRAPP PF04051.11 AEO57448.1 - 4.6e-45 152.8 0.0 5.5e-45 152.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PINIT PF14324.1 AEO57449.1 - 6e-46 156.1 0.0 1.2e-45 155.1 0.0 1.5 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 AEO57449.1 - 1.7e-22 78.6 5.5 3e-22 77.8 3.8 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.22 AEO57449.1 - 3e-06 26.6 0.0 6.9e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 SAP domain zf-Nse PF11789.3 AEO57449.1 - 4.5e-05 22.8 1.2 0.0001 21.7 0.8 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-Sec23_Sec24 PF04810.10 AEO57449.1 - 0.052 13.1 0.1 0.052 13.1 0.0 2.1 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-C3HC4_4 PF15227.1 AEO57449.1 - 0.11 12.3 5.0 0.22 11.3 3.5 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF2423 PF10338.4 AEO57450.1 - 2.4e-15 56.2 2.8 2.4e-15 56.2 2.0 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF2423) Myb_Cef PF11831.3 AEO57450.1 - 0.015 14.5 5.5 0.017 14.3 3.8 1.2 1 0 0 1 1 1 0 pre-mRNA splicing factor component HMG14_17 PF01101.13 AEO57450.1 - 3.3 8.4 13.9 0.088 13.5 2.5 2.2 1 1 1 2 2 2 0 HMG14 and HMG17 Phosphodiest PF01663.17 AEO57451.1 - 3.1e-12 46.4 0.0 5.1e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 AEO57451.1 - 0.00014 21.2 0.0 0.00022 20.5 0.0 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 AEO57451.1 - 0.0005 19.5 0.0 0.00097 18.5 0.0 1.4 1 1 0 1 1 1 1 Metalloenzyme superfamily Cnd3 PF12719.2 AEO57452.1 - 2.9e-96 321.9 1.2 1.4e-95 319.7 0.1 2.4 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 AEO57452.1 - 1.4e-12 47.6 10.2 9.3e-06 25.8 1.0 5.4 3 1 2 5 5 5 4 HEAT repeats HEAT PF02985.17 AEO57452.1 - 2.6e-07 30.1 8.7 0.11 12.6 0.0 7.0 6 0 0 6 6 6 2 HEAT repeat MMS19_N PF14500.1 AEO57452.1 - 0.0061 15.8 0.3 0.26 10.4 0.0 3.1 2 1 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II DUF1546 PF07571.8 AEO57452.1 - 0.028 14.5 0.3 3.1 7.9 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1546) HEAT_EZ PF13513.1 AEO57452.1 - 7.2 7.2 23.7 0.4 11.2 1.1 7.0 4 1 3 7 7 7 0 HEAT-like repeat RRM_1 PF00076.17 AEO57453.1 - 7.9e-60 198.4 0.0 4.5e-19 67.8 0.0 6.2 6 0 0 6 6 6 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO57453.1 - 2.4e-47 158.7 0.2 8.4e-14 51.3 0.0 6.2 6 0 0 6 6 6 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO57453.1 - 2.5e-23 81.6 0.0 1.1e-08 34.7 0.0 4.8 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2540 PF10802.3 AEO57453.1 - 0.069 12.8 0.2 0.18 11.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2540) DUF3439 PF11921.3 AEO57454.1 - 0.19 11.5 5.7 0.36 10.5 3.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mg_trans_NIPA PF05653.9 AEO57455.1 - 2.8e-61 207.0 11.2 3.7e-58 196.8 5.2 2.4 3 0 0 3 3 3 2 Magnesium transporter NIPA EmrE PF13536.1 AEO57455.1 - 0.0022 18.1 1.0 0.0022 18.1 0.7 4.5 4 1 0 4 4 4 1 Multidrug resistance efflux transporter LysE PF01810.13 AEO57455.1 - 0.024 13.9 5.3 0.057 12.6 3.7 1.6 1 0 0 1 1 1 0 LysE type translocator F-box PF00646.28 AEO57455.1 - 0.084 12.5 0.6 0.25 11.0 0.4 1.9 1 0 0 1 1 1 0 F-box domain LRR19-TM PF15176.1 AEO57455.1 - 0.13 11.9 0.0 0.37 10.4 0.0 1.8 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain EamA PF00892.15 AEO57455.1 - 6.2 6.8 23.6 0.25 11.3 1.8 3.7 3 1 1 4 4 4 0 EamA-like transporter family DUF948 PF06103.6 AEO57456.1 - 0.023 14.5 0.2 6 6.8 0.0 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) CIAPIN1 PF05093.8 AEO57456.1 - 0.044 13.8 2.3 0.045 13.8 0.4 1.8 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Erf4 PF10256.4 AEO57457.1 - 3e-31 107.7 0.0 3.9e-31 107.3 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family AMP-binding PF00501.23 AEO57458.1 - 3.9e-73 246.2 0.0 5.6e-73 245.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 AEO57458.1 - 2.9e-17 63.3 0.1 6.1e-17 62.3 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Glyco_hydro_1 PF00232.13 AEO57459.1 - 8.2e-156 518.7 0.0 9.9e-156 518.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 GFA PF04828.9 AEO57460.1 - 0.0043 16.9 0.1 0.0099 15.8 0.0 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 AEO57460.1 - 0.36 10.1 3.3 0.2 10.9 0.3 2.0 2 0 0 2 2 2 0 zinc-ribbon domain SSrecog PF03531.9 AEO57461.1 - 6.2e-75 251.3 0.2 3.7e-74 248.8 0.2 2.1 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 AEO57461.1 - 4.6e-25 87.4 0.1 3.7e-24 84.5 0.0 2.3 2 0 0 2 2 2 1 Histone chaperone Rttp106-like DUF2201_N PF13203.1 AEO57461.1 - 0.25 10.4 0.0 0.25 10.4 0.0 2.1 2 0 0 2 2 2 0 Putative metallopeptidase domain Xpo1 PF08389.7 AEO57462.1 - 4e-38 130.6 0.1 4e-38 130.6 0.0 3.4 3 1 1 4 4 4 1 Exportin 1-like protein HEAT PF02985.17 AEO57462.1 - 0.0071 16.3 1.3 21 5.5 0.0 4.8 4 0 0 4 4 4 2 HEAT repeat RE_MjaI PF09568.5 AEO57462.1 - 0.087 12.3 1.4 4.1 6.9 0.0 2.9 3 0 0 3 3 3 0 MjaI restriction endonuclease Peptidase_M18 PF02127.10 AEO57464.1 - 2.8e-169 563.2 0.0 6.6e-111 370.8 0.0 2.0 1 1 1 2 2 2 2 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 AEO57464.1 - 4.9e-05 22.2 0.0 0.00021 20.1 0.0 1.9 3 0 0 3 3 3 1 M42 glutamyl aminopeptidase Binary_toxB PF03495.9 AEO57464.1 - 0.028 13.0 2.5 0.049 12.2 1.8 1.3 1 0 0 1 1 1 0 Clostridial binary toxin B/anthrax toxin PA Whi5 PF08528.6 AEO57467.1 - 6e-11 41.6 0.0 1.4e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 Whi5 like NRDE-2 PF08424.5 AEO57468.1 - 5.6e-89 298.2 0.0 2.7e-86 289.4 0.0 2.3 2 0 0 2 2 2 2 NRDE-2, necessary for RNA interference Voltage_CLC PF00654.15 AEO57469.1 - 8.8e-94 314.4 19.0 8.8e-94 314.4 13.2 2.0 2 0 0 2 2 2 1 Voltage gated chloride channel TAT_signal PF10518.4 AEO57469.1 - 0.014 15.3 3.4 0.014 15.3 2.4 2.8 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence Cation_efflux PF01545.16 AEO57470.1 - 2.9e-54 184.0 4.3 7.5e-47 159.7 1.6 2.1 1 1 0 2 2 2 2 Cation efflux family Zip PF02535.17 AEO57470.1 - 0.0033 16.4 23.4 0.14 11.1 7.6 2.9 2 1 0 2 2 2 2 ZIP Zinc transporter SIR2 PF02146.12 AEO57471.1 - 1.7e-27 96.3 0.0 2.5e-27 95.7 0.0 1.3 1 0 0 1 1 1 1 Sir2 family Peripla_BP_4 PF13407.1 AEO57471.1 - 0.046 13.0 0.1 0.074 12.3 0.1 1.3 1 0 0 1 1 1 0 Periplasmic binding protein domain Peptidase_C50 PF03568.12 AEO57472.1 - 2.5e-112 375.3 0.0 4.1e-112 374.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C50 Apolipoprotein PF01442.13 AEO57475.1 - 0.04 13.4 2.7 4.7 6.6 0.1 2.8 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain PNP_UDP_1 PF01048.15 AEO57476.1 - 3.6e-09 35.9 0.2 9.4e-09 34.5 0.2 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily AAA_22 PF13401.1 AEO57476.1 - 0.00035 20.7 0.0 0.00078 19.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 AEO57476.1 - 0.0038 16.9 0.0 0.0073 15.9 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_25 PF13481.1 AEO57476.1 - 0.014 14.8 0.0 0.032 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 AEO57476.1 - 0.03 14.3 0.2 0.08 12.9 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.24 AEO57476.1 - 0.03 14.5 0.0 0.12 12.5 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zn_clus PF00172.13 AEO57478.1 - 1.7e-07 30.9 7.6 2.9e-07 30.2 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_S8 PF00082.17 AEO57480.1 - 6.8e-22 77.9 1.4 1.8e-21 76.5 1.0 1.6 1 1 0 1 1 1 1 Subtilase family ketoacyl-synt PF00109.21 AEO57481.1 - 1.8e-73 247.1 0.0 3.4e-73 246.2 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.23 AEO57481.1 - 4.8e-72 242.6 0.0 7.7e-72 241.9 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Acyl_transf_1 PF00698.16 AEO57481.1 - 2e-50 171.9 0.2 3.8e-50 171.0 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain Condensation PF00668.15 AEO57481.1 - 1e-49 169.0 0.0 1.4e-49 168.5 0.0 1.2 1 0 0 1 1 1 1 Condensation domain KR PF08659.5 AEO57481.1 - 1.2e-49 168.4 0.0 2.7e-48 164.0 0.0 2.8 2 0 0 2 2 2 1 KR domain PS-DH PF14765.1 AEO57481.1 - 2.5e-46 158.1 0.2 5.9e-46 156.9 0.1 1.7 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 AEO57481.1 - 1.5e-43 148.6 0.0 2.6e-39 134.8 0.0 3.2 2 0 0 2 2 2 2 short chain dehydrogenase NAD_binding_4 PF07993.7 AEO57481.1 - 5.5e-38 130.2 0.1 1.9e-37 128.5 0.1 1.9 1 1 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.17 AEO57481.1 - 1.1e-29 102.6 0.5 5.8e-29 100.3 0.0 2.6 4 0 0 4 4 2 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 AEO57481.1 - 1.3e-19 70.2 0.2 1.9e-11 44.0 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site Epimerase PF01370.16 AEO57481.1 - 1.6e-16 60.4 0.0 1.9e-15 56.9 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_12 PF08242.7 AEO57481.1 - 4.4e-15 55.9 0.0 4.5e-14 52.7 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO57481.1 - 4.1e-13 49.3 0.0 2.9e-12 46.5 0.0 2.4 2 1 1 3 3 3 1 Methyltransferase domain 3Beta_HSD PF01073.14 AEO57481.1 - 1.4e-11 43.6 0.0 5.7e-11 41.6 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_11 PF08241.7 AEO57481.1 - 2.4e-10 40.7 0.0 1.1e-09 38.6 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO57481.1 - 9.5e-08 32.3 0.0 5.1e-07 29.9 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO57481.1 - 2.1e-06 27.4 0.0 4.7e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain HxxPF_rpt PF13745.1 AEO57481.1 - 2.1e-06 27.9 0.0 4.1e-05 23.8 0.0 2.8 2 0 0 2 2 2 1 HxxPF-repeated domain Methyltransf_18 PF12847.2 AEO57481.1 - 2.2e-06 28.1 0.0 1e-05 26.0 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 AEO57481.1 - 3.5e-05 22.9 0.0 7.4e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_26 PF13659.1 AEO57481.1 - 0.00062 19.7 0.0 0.0042 17.1 0.0 2.6 1 0 0 1 1 1 1 Methyltransferase domain Semialdhyde_dh PF01118.19 AEO57481.1 - 0.013 15.7 0.1 0.43 10.8 0.0 3.0 3 0 0 3 3 2 0 Semialdehyde dehydrogenase, NAD binding domain Ubie_methyltran PF01209.13 AEO57481.1 - 0.035 13.2 0.0 0.077 12.0 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 AEO57482.1 - 8e-13 48.6 0.0 1.6e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO57482.1 - 6e-10 39.4 0.0 9.1e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO57482.1 - 9.6e-09 35.0 0.0 1.9e-08 34.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO57482.1 - 2.9e-05 24.5 0.0 6.6e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO57482.1 - 5.8e-05 23.3 0.0 0.00012 22.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AEO57482.1 - 0.00014 21.0 0.0 0.00023 20.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 AEO57482.1 - 0.00018 21.2 0.0 0.00046 19.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO57482.1 - 0.002 18.1 0.1 0.0047 16.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DIOX_N PF14226.1 AEO57483.1 - 1.9e-20 73.5 0.0 3.4e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 AEO57483.1 - 2.8e-13 50.0 0.0 4.5e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily P5CR_dimer PF14748.1 AEO57484.1 - 1e-27 96.2 7.5 2.1e-27 95.2 5.2 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 AEO57484.1 - 1.3e-05 25.5 0.1 5.9e-05 23.4 0.0 2.1 2 1 1 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent ADH_N PF08240.7 AEO57486.1 - 2.3e-28 98.0 2.4 4e-28 97.3 1.7 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AEO57486.1 - 2.4e-15 56.2 0.0 3.5e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 AEO57486.1 - 0.0058 16.2 0.0 0.017 14.7 0.0 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated DUF3399 PF11879.3 AEO57486.1 - 0.17 12.1 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3399) Epimerase PF01370.16 AEO57487.1 - 1.4e-06 27.9 0.1 0.037 13.4 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 AEO57487.1 - 0.00021 20.2 0.0 0.00041 19.3 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.19 AEO57487.1 - 0.00033 20.9 0.0 0.00062 20.0 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 AEO57487.1 - 0.0043 16.3 0.0 0.0087 15.3 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family p450 PF00067.17 AEO57488.1 - 2.4e-54 184.6 0.0 3.3e-54 184.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_6 PF12697.2 AEO57489.1 - 7.9e-16 58.6 4.7 2.8e-14 53.5 0.9 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO57489.1 - 7.8e-10 38.6 0.0 3.1e-09 36.7 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF1100 PF06500.6 AEO57489.1 - 4.9e-06 25.3 0.0 6.6e-06 24.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S9 PF00326.16 AEO57489.1 - 0.0019 17.4 0.0 0.0041 16.3 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 AEO57489.1 - 0.0032 16.9 0.0 0.0057 16.1 0.0 1.5 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.8 AEO57489.1 - 0.011 15.3 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold UPF0227 PF05728.7 AEO57489.1 - 0.017 14.8 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Esterase PF00756.15 AEO57489.1 - 0.02 14.2 0.0 0.078 12.3 0.0 1.9 2 0 0 2 2 2 0 Putative esterase Abhydrolase_1 PF00561.15 AEO57489.1 - 0.082 12.4 0.3 0.25 10.8 0.2 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold MFS_1 PF07690.11 AEO57490.1 - 1.1e-41 142.7 58.8 1.1e-41 142.7 40.8 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO57490.1 - 1e-10 40.8 15.5 1e-10 40.8 10.7 3.7 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 AEO57490.1 - 1.3e-09 36.8 23.1 2.3e-09 35.9 16.0 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3392 PF11872.3 AEO57490.1 - 0.37 10.7 6.7 2.5 8.1 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3392) ADH_zinc_N PF00107.21 AEO57491.1 - 1.1e-07 31.4 0.3 2.3e-07 30.4 0.1 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AEO57491.1 - 0.00032 20.4 0.1 0.0018 17.9 0.0 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain IncA PF04156.9 AEO57492.1 - 1.4e-05 24.7 18.2 2.4e-05 24.0 0.2 3.4 1 1 2 3 3 3 1 IncA protein Baculo_PEP_C PF04513.7 AEO57492.1 - 0.0014 18.4 1.2 0.12 12.1 0.1 3.0 2 1 1 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.6 AEO57492.1 - 0.0014 18.4 4.0 0.62 9.9 0.1 3.7 2 1 1 3 3 3 1 Bacterial protein of unknown function (DUF948) AAA_13 PF13166.1 AEO57492.1 - 0.0021 16.6 7.7 0.0021 16.6 5.3 2.0 1 1 1 2 2 2 2 AAA domain Prominin PF05478.6 AEO57492.1 - 0.004 14.7 4.7 0.59 7.6 1.9 2.8 2 1 0 2 2 2 1 Prominin TMF_TATA_bd PF12325.3 AEO57492.1 - 0.0049 16.6 8.5 3.5 7.3 0.3 4.0 4 0 0 4 4 4 0 TATA element modulatory factor 1 TATA binding Laminin_I PF06008.9 AEO57492.1 - 0.0057 16.0 4.7 0.019 14.3 0.4 2.4 2 0 0 2 2 2 1 Laminin Domain I HALZ PF02183.13 AEO57492.1 - 0.008 15.8 2.6 5.3 6.8 0.2 3.5 3 0 0 3 3 3 0 Homeobox associated leucine zipper Bacillus_HBL PF05791.6 AEO57492.1 - 0.011 15.1 14.4 0.035 13.4 3.1 2.8 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) DUF148 PF02520.12 AEO57492.1 - 0.014 15.2 10.1 0.027 14.2 0.6 3.3 2 1 1 3 3 3 0 Domain of unknown function DUF148 Prefoldin_2 PF01920.15 AEO57492.1 - 0.015 15.0 14.5 0.26 11.0 0.7 4.0 3 1 1 4 4 4 0 Prefoldin subunit UPF0149 PF03695.8 AEO57492.1 - 0.018 14.9 0.9 0.039 13.8 0.6 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0149) CENP-H PF05837.7 AEO57492.1 - 0.018 15.2 6.6 0.055 13.6 0.7 2.5 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Reo_sigmaC PF04582.7 AEO57492.1 - 0.019 14.1 1.4 1.7 7.7 0.0 2.6 2 1 1 3 3 3 0 Reovirus sigma C capsid protein FlaC_arch PF05377.6 AEO57492.1 - 0.027 14.3 5.0 2.7 7.9 0.0 3.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Seryl_tRNA_N PF02403.17 AEO57492.1 - 0.029 14.3 16.5 1.1 9.3 0.5 3.9 2 1 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.10 AEO57492.1 - 0.029 13.8 10.9 1.4 8.4 0.2 3.5 3 0 0 3 3 3 0 Septum formation initiator MbeD_MobD PF04899.7 AEO57492.1 - 0.03 14.2 1.2 0.088 12.7 0.1 2.3 2 0 0 2 2 2 0 MbeD/MobD like THP2 PF09432.5 AEO57492.1 - 0.038 13.8 0.5 0.038 13.8 0.3 2.4 4 0 0 4 4 1 0 Tho complex subunit THP2 HalX PF08663.5 AEO57492.1 - 0.038 13.9 6.1 1.5 8.8 0.2 3.5 3 0 0 3 3 3 0 HalX domain WXG100 PF06013.7 AEO57492.1 - 0.049 13.6 2.7 2.8 7.9 0.2 3.6 3 1 0 3 3 3 0 Proteins of 100 residues with WXG V-SNARE PF05008.10 AEO57492.1 - 0.08 13.1 9.8 0.61 10.2 0.4 3.5 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus DUF3450 PF11932.3 AEO57492.1 - 0.083 12.1 5.0 1.7 7.8 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) RhoGEF PF00621.15 AEO57492.1 - 0.085 12.7 3.8 0.17 11.7 2.2 1.8 1 1 0 1 1 1 0 RhoGEF domain DUF1517 PF07466.6 AEO57492.1 - 0.085 11.8 0.1 0.13 11.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) GrpE PF01025.14 AEO57492.1 - 0.086 12.3 14.3 1.3 8.5 0.3 4.4 2 1 2 4 4 4 0 GrpE OPA3 PF07047.7 AEO57492.1 - 0.089 12.5 1.8 1 9.1 0.0 2.9 3 0 0 3 3 3 0 Optic atrophy 3 protein (OPA3) Prefoldin PF02996.12 AEO57492.1 - 0.092 12.3 10.8 0.47 10.1 0.2 3.7 3 1 0 3 3 3 0 Prefoldin subunit RmuC PF02646.11 AEO57492.1 - 0.093 11.5 7.7 2.1 7.1 0.2 3.7 2 1 2 4 4 4 0 RmuC family DUF4200 PF13863.1 AEO57492.1 - 0.12 12.2 16.3 0.082 12.8 1.9 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) DUF1664 PF07889.7 AEO57492.1 - 0.13 12.1 9.7 3.9 7.2 0.2 3.7 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) Syntaxin-6_N PF09177.6 AEO57492.1 - 0.13 12.7 12.4 2.7 8.4 0.9 3.7 2 1 2 4 4 3 0 Syntaxin 6, N-terminal ApoO PF09769.4 AEO57492.1 - 0.13 11.9 0.6 5.5 6.6 0.0 2.5 2 1 1 3 3 2 0 Apolipoprotein O DUF4446 PF14584.1 AEO57492.1 - 0.14 11.9 2.9 9.1 6.0 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) DUF1706 PF08020.6 AEO57492.1 - 0.18 11.3 2.0 0.83 9.1 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1706) Syntaxin_2 PF14523.1 AEO57492.1 - 0.2 11.6 11.5 0.87 9.6 0.8 3.3 3 0 0 3 3 3 0 Syntaxin-like protein Cytochrom_B562 PF07361.6 AEO57492.1 - 0.21 12.0 0.1 0.21 12.0 0.1 3.4 2 1 1 3 3 3 0 Cytochrome b562 Ax_dynein_light PF10211.4 AEO57492.1 - 0.25 11.1 10.6 0.11 12.2 1.5 2.7 2 1 0 2 2 2 0 Axonemal dynein light chain MRP-S27 PF10037.4 AEO57492.1 - 0.26 10.1 7.5 0.04 12.8 2.3 1.6 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S27 Fib_alpha PF08702.5 AEO57492.1 - 0.27 11.3 8.9 1.1 9.3 2.2 2.9 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF479 PF04336.7 AEO57492.1 - 0.28 11.2 2.2 1.3 9.1 0.1 2.8 3 1 0 3 3 2 0 Protein of unknown function, DUF479 ERM PF00769.14 AEO57492.1 - 0.38 10.2 9.1 0.6 9.6 0.5 2.4 2 1 0 2 2 2 0 Ezrin/radixin/moesin family TPR_MLP1_2 PF07926.7 AEO57492.1 - 0.4 10.4 14.1 0.61 9.8 3.3 2.8 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4140 PF13600.1 AEO57492.1 - 0.45 10.9 10.9 1.6 9.1 0.2 3.8 3 1 1 4 4 4 0 N-terminal domain of unknown function (DUF4140) Transposase_22 PF02994.9 AEO57492.1 - 0.47 8.9 9.9 0.87 8.0 2.1 2.5 2 1 0 2 2 2 0 L1 transposable element OmpH PF03938.9 AEO57492.1 - 0.49 10.3 10.8 4.3 7.2 0.1 3.1 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) Spectrin PF00435.16 AEO57492.1 - 0.58 10.4 19.0 0.17 12.1 2.0 4.0 2 1 2 4 4 4 0 Spectrin repeat Pox_A_type_inc PF04508.7 AEO57492.1 - 0.69 9.8 6.5 1.3 8.9 0.0 3.5 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Med4 PF10018.4 AEO57492.1 - 0.7 9.2 8.9 13 5.1 3.5 3.2 2 1 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 FlxA PF14282.1 AEO57492.1 - 1.1 9.2 16.3 0.27 11.1 0.4 3.8 3 1 0 3 3 3 0 FlxA-like protein Bap31 PF05529.7 AEO57492.1 - 1.3 8.4 6.4 6.4 6.1 1.4 2.4 2 1 0 2 2 2 0 B-cell receptor-associated protein 31-like DUF4559 PF15112.1 AEO57492.1 - 1.3 8.0 8.8 6.6 5.7 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4559) TBPIP PF07106.8 AEO57492.1 - 1.5 8.3 14.2 2.8 7.4 3.7 3.5 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) COG5 PF10392.4 AEO57492.1 - 1.7 8.6 5.9 1.2 9.1 0.3 3.0 2 1 1 3 3 3 0 Golgi transport complex subunit 5 Lectin_N PF03954.9 AEO57492.1 - 1.8 7.9 7.0 1.1 8.6 0.1 2.8 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain ZapA PF05164.8 AEO57492.1 - 2 8.4 5.8 37 4.3 0.0 3.8 4 1 0 4 4 3 0 Cell division protein ZapA FliD_C PF07195.7 AEO57492.1 - 2.1 7.5 9.4 1 8.6 3.3 2.5 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Val_tRNA-synt_C PF10458.4 AEO57492.1 - 2.8 8.0 10.0 25 5.0 0.1 3.5 3 0 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm ADIP PF11559.3 AEO57492.1 - 2.8 7.8 14.7 5.7 6.8 0.4 3.6 2 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding Tropomyosin_1 PF12718.2 AEO57492.1 - 8.5 6.2 19.6 3.5 7.4 2.9 3.2 2 1 0 2 2 2 0 Tropomyosin like UPF0449 PF15136.1 AEO57492.1 - 8.7 6.6 13.1 81 3.5 1.6 4.1 3 1 0 3 3 3 0 Uncharacterised protein family UPF0449 DUF1049 PF06305.6 AEO57492.1 - 9.4 5.7 7.6 2 7.9 0.1 3.2 3 1 1 4 4 3 0 Protein of unknown function (DUF1049) NPV_P10 PF05531.7 AEO57492.1 - 9.8 6.5 9.6 8.3 6.7 0.2 3.9 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein MFS_1 PF07690.11 AEO57494.1 - 1.9e-30 105.8 67.1 5.7e-26 91.0 34.0 3.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO57494.1 - 7.7e-09 34.6 9.3 7.7e-09 34.6 6.4 3.4 2 1 0 3 3 3 2 Sugar (and other) transporter COesterase PF00135.23 AEO57496.1 - 7.8e-10 38.0 0.0 7.4e-08 31.5 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Glyco_hyd_65N_2 PF14498.1 AEO57497.1 - 7.7e-54 182.8 0.2 1.2e-53 182.2 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain AAA PF00004.24 AEO57499.1 - 3e-11 43.6 0.0 5.6e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AEO57499.1 - 0.00036 20.6 0.2 0.0038 17.3 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 AEO57499.1 - 0.0074 17.1 0.2 0.021 15.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AEO57499.1 - 0.0097 15.9 0.3 0.034 14.1 0.0 1.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 AEO57499.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 AEO57499.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain CPT PF07931.7 AEO57499.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Fungal_trans PF04082.13 AEO57500.1 - 2.7e-28 98.5 0.0 5.5e-28 97.5 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO57500.1 - 2.8e-09 36.7 10.8 4.3e-09 36.1 7.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Kri1 PF05178.7 AEO57501.1 - 4.6e-28 97.4 25.2 4.6e-28 97.4 17.4 6.3 5 2 1 6 6 6 1 KRI1-like family Kri1_C PF12936.2 AEO57501.1 - 4.1e-27 93.9 0.2 4.1e-27 93.9 0.2 4.7 6 0 0 6 6 6 1 KRI1-like family C-terminal DUF4381 PF14316.1 AEO57501.1 - 0.22 11.6 5.2 1.5 8.9 0.9 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Ras PF00071.17 AEO57502.1 - 3.8e-58 195.4 0.0 4.5e-58 195.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AEO57502.1 - 3.5e-20 72.6 0.0 5.1e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AEO57502.1 - 2.2e-13 49.8 0.0 3.1e-13 49.3 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 AEO57502.1 - 3.5e-06 26.5 0.0 8.5e-06 25.3 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 AEO57502.1 - 1.5e-05 24.2 0.0 1.7e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 AEO57502.1 - 0.00012 22.0 0.0 0.00019 21.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 AEO57502.1 - 0.0037 17.2 0.0 0.013 15.4 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 AEO57502.1 - 0.064 13.4 0.0 0.22 11.6 0.0 1.9 2 1 0 2 2 2 0 AAA domain zf-C3HC4_3 PF13920.1 AEO57503.1 - 6.3e-05 22.5 11.3 9.3e-05 22.0 7.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 AEO57503.1 - 0.0036 17.0 6.3 0.0048 16.6 4.4 1.2 1 0 0 1 1 1 1 zf-RING of BARD1-type protein U-box PF04564.10 AEO57503.1 - 0.0072 16.2 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 U-box domain zf-RING_5 PF14634.1 AEO57503.1 - 0.034 13.8 12.5 0.052 13.2 8.7 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 AEO57503.1 - 0.11 12.5 13.3 0.19 11.7 9.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) YndJ PF14158.1 AEO57504.1 - 0.098 11.7 5.4 0.15 11.1 3.7 1.1 1 0 0 1 1 1 0 YndJ-like protein MMR_HSR1 PF01926.18 AEO57505.1 - 1.5e-05 24.9 0.0 4.6e-05 23.3 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.13 AEO57505.1 - 2.7e-05 23.3 0.0 0.0006 18.9 0.0 2.1 1 1 0 1 1 1 1 Septin Miro PF08477.8 AEO57505.1 - 0.0006 20.2 0.1 0.0011 19.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein FtsK_SpoIIIE PF01580.13 AEO57505.1 - 0.0017 17.8 0.0 0.0028 17.1 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family DUF258 PF03193.11 AEO57505.1 - 0.0022 17.1 0.3 0.0067 15.6 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 CDC45 PF02724.9 AEO57505.1 - 0.0035 15.4 1.0 0.0058 14.7 0.7 1.4 2 0 0 2 2 2 1 CDC45-like protein AAA_22 PF13401.1 AEO57505.1 - 0.007 16.5 0.1 0.013 15.6 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 AEO57505.1 - 0.0076 16.4 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 AEO57505.1 - 0.0077 15.8 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AEO57505.1 - 0.0095 15.9 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 AEO57505.1 - 0.01 15.3 0.1 0.025 14.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 AEO57505.1 - 0.018 15.3 0.0 0.042 14.1 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.7 AEO57505.1 - 0.019 14.0 0.0 0.034 13.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 AEO57505.1 - 0.025 14.8 2.9 0.3 11.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 AEO57505.1 - 0.039 12.8 0.1 0.072 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) MCM PF00493.18 AEO57505.1 - 0.061 12.1 0.0 0.095 11.4 0.0 1.2 1 0 0 1 1 1 0 MCM2/3/5 family NACHT PF05729.7 AEO57505.1 - 0.072 12.7 0.1 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Hpr_kinase_C PF07475.7 AEO57505.1 - 0.076 12.3 0.1 0.12 11.6 0.1 1.2 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain NTPase_1 PF03266.10 AEO57505.1 - 0.078 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 NTPase UPF0079 PF02367.12 AEO57505.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activat PF00158.21 AEO57505.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain MobB PF03205.9 AEO57505.1 - 0.12 12.0 0.1 0.2 11.3 0.1 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 AEO57505.1 - 0.13 12.1 2.5 0.21 11.3 0.1 2.4 2 1 0 2 2 2 0 Dynamin family AAA_17 PF13207.1 AEO57505.1 - 0.24 12.2 0.1 0.24 12.2 0.0 1.7 2 0 0 2 2 1 0 AAA domain Daxx PF03344.10 AEO57505.1 - 0.38 9.1 12.5 0.6 8.5 8.7 1.2 1 0 0 1 1 1 0 Daxx Family Hid1 PF12722.2 AEO57505.1 - 8.1 3.9 7.4 11 3.4 5.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Period_C PF12114.3 AEO57506.1 - 0.0011 18.5 0.9 0.0011 18.5 0.7 2.0 2 0 0 2 2 2 1 Period protein 2/3C-terminal region Zip PF02535.17 AEO57506.1 - 0.053 12.5 1.1 0.058 12.3 0.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter GCV_T PF01571.16 AEO57508.1 - 3.6e-15 55.9 0.1 1.5e-13 50.5 0.0 2.6 2 1 0 2 2 2 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 AEO57508.1 - 0.041 13.9 0.0 0.081 12.9 0.0 1.6 1 0 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain DnaJ PF00226.26 AEO57509.1 - 9.6e-12 44.4 0.4 9.6e-12 44.4 0.3 2.3 2 0 0 2 2 2 1 DnaJ domain DIOX_N PF14226.1 AEO57510.1 - 3.8e-23 82.2 0.0 6.3e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 AEO57510.1 - 3.4e-16 59.3 0.0 5.4e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HNOB PF07700.10 AEO57510.1 - 0.18 11.2 0.0 0.33 10.4 0.0 1.3 1 0 0 1 1 1 0 Heme NO binding Amidohydro_2 PF04909.9 AEO57511.1 - 4.7e-37 128.0 2.3 5.5e-37 127.8 1.6 1.1 1 0 0 1 1 1 1 Amidohydrolase DEAD PF00270.24 AEO57512.1 - 1.1e-41 142.1 0.0 3.2e-41 140.6 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO57512.1 - 1.3e-27 95.4 0.1 2.7e-27 94.4 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 AEO57512.1 - 1.5e-05 23.9 0.0 2.4e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 AEO57512.1 - 0.026 14.3 0.0 0.062 13.1 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Pkinase PF00069.20 AEO57513.1 - 1.9e-60 204.2 0.0 2.3e-60 203.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO57513.1 - 7.6e-35 120.2 0.0 1e-34 119.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO57513.1 - 1.9e-08 33.6 0.0 2.9e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 AEO57513.1 - 0.26 10.0 0.1 0.38 9.5 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 TruD PF01142.13 AEO57514.1 - 4.5e-54 183.5 0.0 3e-50 170.9 0.0 3.4 3 1 0 3 3 3 2 tRNA pseudouridine synthase D (TruD) DUF1707 PF08044.6 AEO57514.1 - 0.024 14.3 0.6 0.078 12.7 0.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1707) CH PF00307.26 AEO57515.1 - 2e-39 133.9 0.4 9.6e-20 70.6 0.0 2.9 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 AEO57515.1 - 1.4e-26 92.2 0.0 7.2e-26 89.9 0.0 2.4 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 AEO57515.1 - 1.5e-12 46.9 1.3 3.1e-07 29.9 0.0 3.2 3 0 0 3 3 3 2 CAMSAP CH domain EF-hand_6 PF13405.1 AEO57515.1 - 5.6e-05 22.6 0.2 0.00079 19.1 0.1 2.9 2 0 0 2 2 2 1 EF-hand domain Spectrin PF00435.16 AEO57515.1 - 0.00021 21.5 4.1 0.03 14.5 1.4 2.6 2 0 0 2 2 2 2 Spectrin repeat EF-hand_8 PF13833.1 AEO57515.1 - 0.00025 20.6 0.7 0.0037 16.8 0.1 2.8 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.27 AEO57515.1 - 0.0014 17.8 0.3 0.013 14.7 0.0 2.6 2 0 0 2 2 2 1 EF hand DUF1943 PF09172.6 AEO57515.1 - 0.033 13.0 0.1 0.062 12.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) EF-hand_7 PF13499.1 AEO57515.1 - 0.058 13.5 3.8 0.078 13.1 1.1 2.4 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.1 AEO57515.1 - 0.071 12.4 0.1 0.2 11.0 0.1 1.8 1 0 0 1 1 1 0 EF hand VPS9 PF02204.13 AEO57516.1 - 9e-24 83.4 0.1 1.7e-23 82.5 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain K_oxygenase PF13434.1 AEO57516.1 - 0.29 10.0 1.4 0.78 8.5 1.0 1.6 1 1 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Lipase_3 PF01764.20 AEO57517.1 - 1.4e-06 28.0 0.0 2.6e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 AEO57517.1 - 0.028 14.1 0.0 0.078 12.7 0.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family UPF0227 PF05728.7 AEO57517.1 - 0.045 13.4 0.0 0.077 12.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) zf-C3HC4 PF00097.20 AEO57518.1 - 1.4e-07 31.0 2.7 1.4e-07 31.0 1.9 5.3 7 0 0 7 7 7 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AEO57518.1 - 4.9e-07 29.4 5.5 4.9e-07 29.4 3.8 4.1 4 2 1 5 5 5 1 Ring finger domain zf-C3HC4_2 PF13923.1 AEO57518.1 - 7.1e-06 25.9 4.5 7.1e-06 25.9 3.1 4.9 4 2 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO57518.1 - 3.8e-05 23.3 2.3 3.8e-05 23.3 1.6 4.8 6 1 0 6 6 6 1 zinc-RING finger domain zf-RING_6 PF14835.1 AEO57518.1 - 6.8e-05 22.5 0.3 6.8e-05 22.5 0.2 3.4 4 0 0 4 4 4 2 zf-RING of BARD1-type protein SH3_9 PF14604.1 AEO57518.1 - 0.00059 19.3 0.1 0.00059 19.3 0.1 2.4 2 0 0 2 2 2 1 Variant SH3 domain zf-C3HC4_4 PF15227.1 AEO57518.1 - 0.00095 18.9 4.7 0.00095 18.9 3.3 4.5 6 1 0 6 6 6 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 AEO57518.1 - 0.0013 18.3 1.6 0.0031 17.2 1.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger SH3_1 PF00018.23 AEO57518.1 - 0.0032 16.8 0.0 0.0068 15.7 0.0 1.6 1 0 0 1 1 1 1 SH3 domain ECH PF00378.15 AEO57519.1 - 6.2e-70 235.1 0.1 7.7e-70 234.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 AEO57519.1 - 0.0043 17.1 0.1 0.013 15.5 0.0 1.8 2 0 0 2 2 2 1 2-enoyl-CoA Hydratase C-terminal region Rer1 PF03248.8 AEO57520.1 - 2.1e-82 274.9 6.0 2.4e-82 274.8 4.1 1.0 1 0 0 1 1 1 1 Rer1 family Paf1 PF03985.8 AEO57521.1 - 3.8e-59 200.5 3.0 1.4e-58 198.6 2.1 1.7 1 1 0 1 1 1 1 Paf1 MIP-T3 PF10243.4 AEO57522.1 - 1.6 7.0 77.6 3 6.2 53.8 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PAT1 PF09770.4 AEO57522.1 - 1.8 6.7 101.0 2.8 6.0 70.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CAF-1_p150 PF11600.3 AEO57522.1 - 9.4 5.5 72.3 0.14 11.4 44.7 1.8 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ribosomal_S8 PF00410.14 AEO57523.1 - 2.5e-25 88.8 0.0 3.3e-25 88.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_L7Ae PF01248.21 AEO57524.1 - 1.5e-28 98.1 0.7 1.9e-28 97.8 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PucR PF07905.6 AEO57524.1 - 0.086 12.4 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family Rotamase_3 PF13616.1 AEO57525.1 - 0.00024 21.3 0.1 0.00024 21.3 0.1 2.1 1 1 1 2 2 2 1 PPIC-type PPIASE domain Rotamase PF00639.16 AEO57525.1 - 0.0078 16.9 0.1 0.0078 16.9 0.1 2.0 2 1 1 3 3 3 1 PPIC-type PPIASE domain Mtf2_C PF14061.1 AEO57525.1 - 0.057 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 Neurochondrin PF05536.6 AEO57527.1 - 1.6e-108 363.4 0.0 8.4e-107 357.7 0.0 2.1 1 1 0 1 1 1 1 Neurochondrin RIX1 PF08167.7 AEO57527.1 - 0.35 10.5 5.5 0.15 11.7 0.2 3.0 3 1 0 3 3 3 0 rRNA processing/ribosome biogenesis Pkinase PF00069.20 AEO57528.1 - 0.08 12.0 0.1 0.083 12.0 0.0 1.0 1 0 0 1 1 1 0 Protein kinase domain Voltage_CLC PF00654.15 AEO57529.1 - 3.4e-92 309.1 25.2 5.7e-92 308.4 17.5 1.3 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.23 AEO57529.1 - 4e-07 29.7 0.0 0.0031 17.2 0.0 2.6 2 0 0 2 2 2 2 CBS domain TCTP PF00838.12 AEO57532.1 - 2e-69 232.7 4.9 2.3e-69 232.6 3.4 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Mus7 PF09462.5 AEO57532.1 - 0.11 11.3 0.1 0.13 11.0 0.1 1.0 1 0 0 1 1 1 0 Mus7/MMS22 family MSP PF01716.13 AEO57532.1 - 0.16 11.0 2.5 3.8 6.4 0.3 2.2 2 0 0 2 2 2 0 Manganese-stabilising protein / photosystem II polypeptide FA_hydroxylase PF04116.8 AEO57533.1 - 1.2e-17 64.3 11.4 1.2e-17 64.3 7.9 2.1 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily 2-Hacid_dh_C PF02826.14 AEO57534.1 - 2.1e-43 147.5 0.0 7.8e-32 109.8 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DcpS_C PF11969.3 AEO57534.1 - 5.4e-17 62.0 1.7 8.2e-17 61.4 1.2 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 AEO57534.1 - 4.7e-06 27.0 0.2 9.8e-06 26.0 0.1 1.5 1 0 0 1 1 1 1 HIT domain TrkA_N PF02254.13 AEO57534.1 - 0.0028 17.6 0.1 0.65 10.0 0.0 2.6 2 0 0 2 2 2 1 TrkA-N domain Gp_dh_N PF00044.19 AEO57534.1 - 0.0083 16.0 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain F420_oxidored PF03807.12 AEO57534.1 - 0.044 14.2 0.1 0.11 12.9 0.0 1.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 AEO57534.1 - 0.085 12.9 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 AEO57534.1 - 0.16 11.8 0.2 0.28 11.0 0.1 1.4 1 0 0 1 1 1 0 ThiF family Glyco_hydro_19 PF00182.14 AEO57535.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Chitinase class I PPR_2 PF13041.1 AEO57536.1 - 2.9e-26 91.1 0.0 7.1e-06 25.9 0.1 7.1 6 1 1 7 7 7 5 PPR repeat family PPR_3 PF13812.1 AEO57536.1 - 3.4e-19 67.4 5.1 0.066 13.5 0.0 10.0 10 0 0 10 10 10 4 Pentatricopeptide repeat domain PPR PF01535.15 AEO57536.1 - 2.2e-16 58.6 1.4 0.0049 16.7 0.0 7.0 7 0 0 7 7 7 4 PPR repeat PPR_1 PF12854.2 AEO57536.1 - 2.3e-09 36.5 2.8 0.0031 16.9 0.0 5.6 6 0 0 6 6 6 2 PPR repeat His_Phos_2 PF00328.17 AEO57537.1 - 8.1e-23 81.2 0.0 7e-22 78.2 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) ATP-synt_D PF01813.12 AEO57538.1 - 0.018 14.5 0.3 0.068 12.7 0.0 1.9 2 0 0 2 2 2 0 ATP synthase subunit D DUF2360 PF10152.4 AEO57538.1 - 3.8 7.7 7.9 3.3 7.9 1.9 2.6 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF3439 PF11921.3 AEO57538.1 - 4.4 7.0 8.0 7.9 6.2 5.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Med3 PF11593.3 AEO57538.1 - 8.1 5.5 7.5 2.3 7.3 2.4 1.8 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Ras PF00071.17 AEO57539.1 - 1.5e-52 177.2 0.0 1.8e-52 177.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AEO57539.1 - 7.2e-16 58.7 0.0 1.3e-15 57.9 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AEO57539.1 - 1.4e-05 24.4 0.0 2e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family tRNA-synt_2 PF00152.15 AEO57540.1 - 4.5e-72 242.6 0.2 7e-72 242.0 0.2 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 AEO57540.1 - 1.5e-05 24.7 0.0 2.8e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain KfrA_N PF11740.3 AEO57540.1 - 0.074 13.4 4.3 0.16 12.4 3.0 1.5 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term DUF342 PF03961.8 AEO57540.1 - 0.13 10.6 2.0 0.24 9.7 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF342) RRM_6 PF14259.1 AEO57541.1 - 1e-41 140.7 0.0 4.9e-12 45.6 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AEO57541.1 - 8.5e-39 131.0 0.1 1.8e-12 46.6 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO57541.1 - 2e-20 72.4 0.0 1.4e-05 24.8 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM PF10378.4 AEO57541.1 - 8.9e-13 47.6 4.2 8.9e-13 47.6 2.9 2.9 3 0 0 3 3 2 1 Putative RRM domain RRM_3 PF08777.6 AEO57541.1 - 0.00018 21.2 5.1 0.011 15.5 0.1 3.3 3 0 0 3 3 3 1 RNA binding motif DUF4523 PF15023.1 AEO57541.1 - 0.0095 15.4 0.0 2.6 7.5 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF4523) RNA_bind PF08675.6 AEO57541.1 - 0.015 15.2 0.0 0.21 11.5 0.0 2.9 3 0 0 3 3 2 0 RNA binding domain Nup35_RRM_2 PF14605.1 AEO57541.1 - 0.033 13.9 0.0 20 5.0 0.0 3.4 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif Folliculin PF11704.3 AEO57541.1 - 0.44 10.1 3.3 0.99 8.9 2.3 1.5 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Spt20 PF12090.3 AEO57541.1 - 2 7.7 8.7 0.39 10.0 2.8 2.0 2 0 0 2 2 2 0 Spt20 family MDFI PF15316.1 AEO57541.1 - 6 6.8 6.0 16 5.4 4.1 1.7 1 0 0 1 1 1 0 MyoD family inhibitor Ctr PF04145.10 AEO57541.1 - 6.9 6.7 5.7 13 5.7 3.5 1.7 1 1 0 1 1 1 0 Ctr copper transporter family Suf PF05843.9 AEO57541.1 - 7.6 6.1 14.5 0.15 11.7 4.7 1.9 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Mis12 PF05859.7 AEO57542.1 - 7e-34 116.7 0.0 2.4e-33 114.9 0.0 2.0 2 1 0 2 2 2 1 Mis12 protein Ribosomal_60s PF00428.14 AEO57542.1 - 0.053 13.9 1.3 0.053 13.9 0.9 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein Serglycin PF04360.7 AEO57542.1 - 3 7.5 6.1 43 3.8 3.2 2.3 2 0 0 2 2 2 0 Serglycin Nucleoplasmin PF03066.10 AEO57542.1 - 6.5 6.2 22.5 0.27 10.7 1.2 4.0 4 0 0 4 4 4 0 Nucleoplasmin YL1 PF05764.8 AEO57543.1 - 2.3e-60 204.1 27.2 2.3e-60 204.1 18.8 2.3 2 0 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.6 AEO57543.1 - 2.2e-15 55.8 1.5 3.9e-15 55.0 1.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain zf-HIT PF04438.11 AEO57543.1 - 0.066 12.8 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 HIT zinc finger PALP PF00291.20 AEO57544.1 - 3.8e-61 206.9 0.1 5.7e-61 206.4 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Ribosomal_L19 PF01245.15 AEO57546.1 - 6.9e-18 64.4 0.2 1.2e-17 63.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 SMN PF06003.7 AEO57546.1 - 0.088 11.8 0.4 0.15 11.1 0.3 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) CAP_N PF01213.14 AEO57546.1 - 0.45 9.7 7.7 0.46 9.7 2.0 2.1 1 1 1 2 2 2 0 Adenylate cyclase associated (CAP) N terminal TrkH PF02386.11 AEO57547.1 - 5.6e-121 403.4 16.7 1.6e-118 395.3 6.9 2.0 2 0 0 2 2 2 2 Cation transport protein Helicase_C_3 PF13625.1 AEO57548.1 - 3.2e-27 94.8 0.0 2.5e-26 91.9 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AEO57548.1 - 4.5e-16 59.2 0.0 9.8e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 AEO57548.1 - 5.3e-11 42.2 0.0 1.3e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 AEO57548.1 - 2.8e-10 39.5 0.1 4.7e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Proteasome PF00227.21 AEO57549.1 - 7.4e-56 188.4 0.1 1.2e-55 187.7 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 AEO57549.1 - 1.8e-12 46.3 0.1 1.8e-12 46.3 0.1 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature FAD-oxidase_C PF02913.14 AEO57550.1 - 1.6e-60 204.5 0.0 2.3e-60 203.9 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 AEO57550.1 - 6e-38 129.4 0.4 1.2e-37 128.4 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain Zn_clus PF00172.13 AEO57551.1 - 2.3e-06 27.3 9.9 4.7e-06 26.4 6.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_ligase_A_M PF01068.16 AEO57552.1 - 9.5e-58 194.9 1.2 2.1e-46 157.8 0.4 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 AEO57552.1 - 2.1e-52 177.5 0.5 5.4e-52 176.1 0.0 2.0 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 AEO57552.1 - 8.8e-28 96.5 0.0 3.2e-27 94.7 0.0 2.1 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region EF-hand_5 PF13202.1 AEO57552.1 - 0.09 12.1 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 EF hand E1_dh PF00676.15 AEO57553.1 - 4.5e-113 376.9 0.2 5.6e-113 376.6 0.1 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 AEO57553.1 - 0.0014 17.6 0.0 0.0022 16.9 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase WD40 PF00400.27 AEO57554.1 - 2.6e-51 169.7 22.9 7.5e-11 41.4 0.3 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 AEO57554.1 - 1.4e-12 47.1 0.8 2.7e-12 46.2 0.5 1.5 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 AEO57554.1 - 2.7e-09 35.7 12.7 0.036 12.2 0.1 5.5 1 1 4 5 5 5 5 Nucleoporin Nup120/160 F-box PF00646.28 AEO57554.1 - 1.3e-05 24.7 1.6 2.5e-05 23.8 1.1 1.5 1 0 0 1 1 1 1 F-box domain Nucleoporin_N PF08801.6 AEO57554.1 - 0.013 14.2 0.5 0.14 10.8 0.2 2.2 1 1 0 2 2 2 0 Nup133 N terminal like Mito_fiss_reg PF05308.6 AEO57554.1 - 0.11 11.8 0.9 0.21 10.9 0.6 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 AEO57554.1 - 0.27 10.4 1.8 1.2 8.3 1.5 1.8 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal PQQ_3 PF13570.1 AEO57554.1 - 0.32 11.3 5.6 10 6.5 0.1 4.6 4 1 1 5 5 5 0 PQQ-like domain Zip PF02535.17 AEO57555.1 - 3.8e-44 150.9 1.9 1.1e-42 146.1 1.3 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter Vma12 PF11712.3 AEO57555.1 - 0.28 10.9 2.0 0.77 9.4 1.4 1.8 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Hat1_N PF10394.4 AEO57556.1 - 3.3e-39 134.5 0.0 6.9e-39 133.4 0.0 1.6 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_7 PF13508.1 AEO57556.1 - 0.0029 17.7 0.0 0.0065 16.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 AEO57556.1 - 0.017 15.1 0.0 0.038 14.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family ROKNT PF08067.6 AEO57556.1 - 0.048 13.5 1.2 0.11 12.3 0.8 1.6 1 0 0 1 1 1 0 ROKNT (NUC014) domain Acetyltransf_10 PF13673.1 AEO57556.1 - 0.091 12.8 0.0 0.28 11.2 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 AEO57556.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein P5CR_dimer PF14748.1 AEO57557.1 - 2.7e-35 120.5 0.9 6e-35 119.4 0.6 1.6 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 AEO57557.1 - 5.9e-15 55.4 2.5 1.1e-12 48.1 0.1 2.7 1 1 1 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent PDH PF02153.12 AEO57557.1 - 0.015 14.2 0.1 0.051 12.4 0.0 1.8 1 1 0 1 1 1 0 Prephenate dehydrogenase NAD_Gly3P_dh_N PF01210.18 AEO57557.1 - 0.032 13.9 3.1 0.15 11.7 2.1 2.0 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 AEO57557.1 - 0.24 10.8 0.0 0.24 10.8 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA CTK3 PF12243.3 AEO57558.1 - 1.1e-59 200.0 1.8 1.5e-59 199.5 1.3 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 AEO57558.1 - 1.4e-21 76.2 12.0 3.9e-21 74.8 8.3 1.8 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus Fib_alpha PF08702.5 AEO57558.1 - 1.3 9.0 4.7 4.9 7.2 0.2 2.5 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Ribosomal_L12 PF00542.14 AEO57559.1 - 3.5e-19 68.5 4.7 5.1e-18 64.8 2.4 2.2 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_60s PF00428.14 AEO57559.1 - 0.013 15.9 7.8 0.013 15.9 5.4 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF3235 PF11574.3 AEO57559.1 - 1.9 8.8 8.0 1.1 9.4 2.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3235) AAA_5 PF07728.9 AEO57560.1 - 3.2e-124 409.2 0.0 1.2e-21 76.9 0.0 9.8 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA PF00004.24 AEO57560.1 - 6.4e-29 100.8 0.0 4.1e-05 23.7 0.0 7.1 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.6 AEO57560.1 - 2e-28 98.6 0.0 7.4e-09 35.3 0.0 7.0 7 0 0 7 7 6 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 AEO57560.1 - 3.1e-28 99.0 20.5 2.9e-05 24.1 0.2 8.6 8 0 0 8 8 6 5 AAA ATPase domain AAA_17 PF13207.1 AEO57560.1 - 9.4e-27 94.2 0.8 0.0025 18.6 0.0 8.7 8 1 0 8 8 6 6 AAA domain AAA_22 PF13401.1 AEO57560.1 - 9.4e-26 90.4 2.1 0.0021 18.2 0.0 9.0 9 1 0 9 9 6 6 AAA domain AAA_33 PF13671.1 AEO57560.1 - 8.8e-24 84.0 1.7 0.0029 17.4 0.0 8.4 8 0 0 8 8 7 5 AAA domain AAA_14 PF13173.1 AEO57560.1 - 1.6e-20 73.2 0.0 0.00025 20.9 0.0 7.6 7 0 0 7 7 6 3 AAA domain Sigma54_activat PF00158.21 AEO57560.1 - 3.7e-20 72.0 0.0 0.0021 17.5 0.0 6.5 6 0 0 6 6 6 4 Sigma-54 interaction domain AAA_18 PF13238.1 AEO57560.1 - 2.5e-19 69.8 0.1 0.017 15.4 0.0 7.1 6 0 0 6 6 6 3 AAA domain Sigma54_activ_2 PF14532.1 AEO57560.1 - 7e-19 68.2 0.6 8.8e-05 22.5 0.0 7.0 6 0 0 6 6 6 3 Sigma-54 interaction domain ABC_tran PF00005.22 AEO57560.1 - 6.9e-17 62.0 5.0 0.0025 18.1 0.0 7.3 7 0 0 7 7 6 3 ABC transporter T2SE PF00437.15 AEO57560.1 - 5.2e-15 55.0 1.2 0.037 12.9 0.0 6.5 6 0 0 6 6 6 3 Type II/IV secretion system protein Zeta_toxin PF06414.7 AEO57560.1 - 7.8e-15 54.5 0.1 0.058 12.4 0.0 7.0 6 0 0 6 6 6 2 Zeta toxin NACHT PF05729.7 AEO57560.1 - 9.5e-15 54.6 2.4 0.18 11.4 0.0 6.5 6 0 0 6 6 5 4 NACHT domain DUF258 PF03193.11 AEO57560.1 - 2.4e-14 52.8 1.2 0.035 13.3 0.0 6.4 6 0 0 6 6 6 3 Protein of unknown function, DUF258 AAA_19 PF13245.1 AEO57560.1 - 7.2e-14 51.3 5.7 0.016 14.9 0.2 6.7 6 0 0 6 6 6 3 Part of AAA domain RNA_helicase PF00910.17 AEO57560.1 - 4.8e-13 49.2 0.2 1.4 9.1 0.0 6.6 6 0 0 6 6 6 1 RNA helicase Arch_ATPase PF01637.13 AEO57560.1 - 5.2e-13 49.2 0.0 0.016 14.9 0.0 6.4 6 0 0 6 6 6 1 Archaeal ATPase AAA_29 PF13555.1 AEO57560.1 - 8.9e-13 47.5 0.1 0.015 14.8 0.0 6.4 6 0 0 6 6 6 1 P-loop containing region of AAA domain UPF0079 PF02367.12 AEO57560.1 - 1.2e-12 47.4 2.9 0.046 13.3 0.0 5.5 5 0 0 5 5 5 3 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 AEO57560.1 - 1.5e-12 47.3 1.1 1.2 8.8 0.0 6.5 6 0 0 6 6 6 2 Molybdopterin guanine dinucleotide synthesis protein B RuvB_N PF05496.7 AEO57560.1 - 2.1e-11 43.3 0.7 0.28 10.1 0.0 6.6 6 0 0 6 6 6 2 Holliday junction DNA helicase ruvB N-terminus Miro PF08477.8 AEO57560.1 - 3.1e-11 43.7 1.5 9.4 6.7 0.0 7.0 6 0 0 6 6 6 0 Miro-like protein AAA_28 PF13521.1 AEO57560.1 - 5.3e-11 42.7 2.9 0.85 9.5 0.0 6.8 6 0 0 6 6 6 2 AAA domain IstB_IS21 PF01695.12 AEO57560.1 - 1.7e-10 40.6 0.2 0.2 11.0 0.0 6.3 6 0 0 6 6 6 2 IstB-like ATP binding protein AAA_25 PF13481.1 AEO57560.1 - 2.7e-10 39.9 0.8 1.3 8.3 0.0 5.9 5 0 0 5 5 5 2 AAA domain SRP54 PF00448.17 AEO57560.1 - 9.3e-10 38.2 2.3 1.1 8.6 0.0 6.8 7 0 0 7 7 7 2 SRP54-type protein, GTPase domain Mg_chelatase PF01078.16 AEO57560.1 - 1.5e-08 34.1 2.5 2.2 7.3 0.0 7.7 8 0 0 8 8 8 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 AEO57560.1 - 1e-07 31.1 2.3 0.85 8.4 0.0 5.7 6 0 0 6 6 6 1 Protein of unknown function (DUF815) PduV-EutP PF10662.4 AEO57560.1 - 1.4e-07 31.0 3.1 0.03 13.7 0.0 5.7 6 0 0 6 6 6 1 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.10 AEO57560.1 - 6e-07 29.3 4.4 0.95 9.1 0.0 5.6 5 0 0 5 5 5 2 NTPase ResIII PF04851.10 AEO57560.1 - 8e-07 29.0 0.0 2.5 7.8 0.0 5.7 6 0 0 6 6 5 0 Type III restriction enzyme, res subunit CbiA PF01656.18 AEO57560.1 - 5.1e-06 26.0 1.5 1.1 8.5 0.0 4.9 5 0 0 5 5 5 1 CobQ/CobB/MinD/ParA nucleotide binding domain Viral_helicase1 PF01443.13 AEO57560.1 - 2.3e-05 24.0 0.0 4.5 6.7 0.0 5.0 5 0 0 5 5 5 0 Viral (Superfamily 1) RNA helicase cobW PF02492.14 AEO57560.1 - 2.4e-05 23.8 5.0 8 5.8 0.0 6.0 6 0 0 6 6 6 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.18 AEO57560.1 - 3.6e-05 23.6 1.1 28 4.6 0.0 6.4 6 0 0 6 6 6 0 50S ribosome-binding GTPase NB-ARC PF00931.17 AEO57560.1 - 4.3e-05 22.5 2.3 4.5 6.0 0.0 5.6 6 0 0 6 6 6 0 NB-ARC domain TIP49 PF06068.8 AEO57560.1 - 6.3e-05 21.8 0.9 3.7 6.1 0.0 5.7 7 0 0 7 7 7 0 TIP49 C-terminus ATP_bind_1 PF03029.12 AEO57560.1 - 7.1e-05 22.4 3.2 3 7.3 0.0 5.6 6 0 0 6 6 6 0 Conserved hypothetical ATP binding protein Bac_DnaA PF00308.13 AEO57560.1 - 7.5e-05 22.4 0.4 12 5.4 0.0 5.1 5 0 0 5 5 5 0 Bacterial dnaA protein AAA_7 PF12775.2 AEO57560.1 - 0.00012 21.2 1.5 7.6 5.5 0.0 4.9 5 0 0 5 5 5 0 P-loop containing dynein motor region D3 AAA_24 PF13479.1 AEO57560.1 - 0.00012 21.7 0.1 31 4.0 0.0 6.1 6 0 0 6 6 6 0 AAA domain Rad17 PF03215.10 AEO57560.1 - 0.00016 20.5 3.7 0.22 10.1 0.0 4.8 6 0 0 6 6 5 1 Rad17 cell cycle checkpoint protein KAP_NTPase PF07693.9 AEO57560.1 - 0.00041 19.4 0.0 8.2 5.3 0.0 5.1 6 0 0 6 6 5 0 KAP family P-loop domain FtsK_SpoIIIE PF01580.13 AEO57560.1 - 0.00047 19.6 0.4 1.5 8.2 0.0 4.9 5 0 0 5 5 5 1 FtsK/SpoIIIE family Dynein_heavy PF03028.10 AEO57560.1 - 0.00062 17.9 0.0 1.7 6.5 0.0 4.3 5 0 0 5 5 5 1 Dynein heavy chain and region D6 of dynein motor DAP3 PF10236.4 AEO57560.1 - 0.0014 17.6 1.4 0.33 9.8 0.0 4.2 5 0 0 5 5 4 1 Mitochondrial ribosomal death-associated protein 3 SRPRB PF09439.5 AEO57560.1 - 0.0021 17.3 2.3 29 3.8 0.0 6.0 7 0 0 7 7 7 0 Signal recognition particle receptor beta subunit DEAD PF00270.24 AEO57560.1 - 0.0021 17.5 0.1 7.7 5.9 0.0 4.8 5 0 0 5 5 5 0 DEAD/DEAH box helicase PhoH PF02562.11 AEO57560.1 - 0.0022 17.2 0.2 7.7 5.6 0.0 4.8 5 0 0 5 5 5 0 PhoH-like protein KaiC PF06745.8 AEO57560.1 - 0.0038 16.3 1.4 5.4 6.0 0.0 5.0 6 0 0 6 6 4 0 KaiC APS_kinase PF01583.15 AEO57560.1 - 0.011 15.4 0.9 0.99 9.0 0.0 4.3 6 0 0 6 6 4 0 Adenylylsulphate kinase ATP-synt_ab PF00006.20 AEO57560.1 - 0.027 13.9 0.0 10 5.5 0.0 4.6 5 1 0 5 5 2 0 ATP synthase alpha/beta family, nucleotide-binding domain VirE PF05272.6 AEO57560.1 - 0.035 13.5 0.0 27 4.1 0.0 4.1 4 0 0 4 4 4 0 Virulence-associated protein E VWA PF00092.23 AEO57560.1 - 0.057 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain Septin PF00735.13 AEO57560.1 - 0.14 11.1 0.6 18 4.2 0.0 3.9 5 0 0 5 5 4 0 Septin ArgK PF03308.11 AEO57560.1 - 0.16 10.7 2.4 11 4.7 0.0 3.4 3 0 0 3 3 3 0 ArgK protein AAA_21 PF13304.1 AEO57560.1 - 0.17 11.8 0.0 30 4.4 0.1 3.6 4 0 0 4 4 3 0 AAA domain Arf PF00025.16 AEO57560.1 - 0.23 10.6 0.5 23 4.1 0.0 4.0 5 0 0 5 5 3 0 ADP-ribosylation factor family Ras PF00071.17 AEO57560.1 - 0.28 10.5 1.7 1.1e+02 2.1 0.0 4.7 5 0 0 5 5 5 0 Ras family PIF1 PF05970.9 AEO57560.1 - 0.47 9.3 0.1 83 1.9 0.0 4.1 5 0 0 5 5 5 0 PIF1-like helicase FeoB_N PF02421.13 AEO57560.1 - 0.5 9.6 0.4 15 4.8 0.0 3.2 3 0 0 3 3 3 0 Ferrous iron transport protein B Hpr_kinase_C PF07475.7 AEO57560.1 - 0.57 9.4 2.7 1.7 7.9 0.1 3.0 4 0 0 4 4 2 0 HPr Serine kinase C-terminal domain PEPCK_ATP PF01293.15 AEO57560.1 - 1 7.7 0.0 3.4 6.0 0.0 1.8 2 0 0 2 2 1 0 Phosphoenolpyruvate carboxykinase Gtr1_RagA PF04670.7 AEO57560.1 - 1 8.4 1.2 80 2.2 0.0 3.9 5 0 0 5 5 4 0 Gtr1/RagA G protein conserved region AAA_6 PF12774.2 AEO57560.1 - 2.7 7.4 0.0 1.9e+02 1.4 0.0 3.8 6 0 0 6 6 2 0 Hydrolytic ATP binding site of dynein motor region D1 Pox_A32 PF04665.7 AEO57560.1 - 3.8 6.7 0.0 1.9e+02 1.1 0.0 3.2 4 0 0 4 4 4 0 Poxvirus A32 protein Strumpellin PF10266.4 AEO57560.1 - 6.3 4.0 0.0 10 3.3 0.0 1.2 1 0 0 1 1 1 0 Hereditary spastic paraplegia protein strumpellin IFNGR1 PF07140.6 AEO57560.1 - 6.4 6.4 0.0 16 5.2 0.0 1.6 1 0 0 1 1 1 0 Interferon gamma receptor (IFNGR1) AAA_15 PF13175.1 AEO57560.1 - 8.9 5.2 0.0 4.6e+02 -0.5 0.0 3.1 5 0 0 5 5 4 0 AAA ATPase domain AAA PF00004.24 AEO57561.1 - 2e-50 170.3 0.0 3.9e-42 143.5 0.0 3.0 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 AEO57561.1 - 9.5e-07 28.3 0.0 6e-05 22.5 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.1 AEO57561.1 - 1.5e-06 28.3 1.1 0.00011 22.2 0.1 3.4 3 1 0 3 3 2 1 AAA ATPase domain AAA_2 PF07724.9 AEO57561.1 - 2.5e-05 24.2 0.0 5.9e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 AEO57561.1 - 5.3e-05 23.3 0.0 0.0024 18.0 0.0 3.0 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 AEO57561.1 - 9.5e-05 22.1 0.2 0.0089 15.7 0.0 3.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 AEO57561.1 - 0.00028 20.7 0.6 0.011 15.5 0.0 3.3 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.7 AEO57561.1 - 0.0023 17.0 0.0 0.033 13.2 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Sigma54_activ_2 PF14532.1 AEO57561.1 - 0.0043 17.1 0.0 0.12 12.4 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain TIP49 PF06068.8 AEO57561.1 - 0.0074 15.0 0.0 0.015 14.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_18 PF13238.1 AEO57561.1 - 0.0074 16.5 0.2 0.056 13.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 AEO57561.1 - 0.0091 16.8 2.8 0.027 15.2 0.0 3.2 4 0 0 4 4 2 1 AAA domain RNA_helicase PF00910.17 AEO57561.1 - 0.0095 16.0 0.0 0.029 14.5 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.1 AEO57561.1 - 0.0098 15.7 0.0 0.045 13.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 AEO57561.1 - 0.015 14.4 0.2 0.13 11.3 0.1 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Bromodomain PF00439.20 AEO57561.1 - 0.023 14.6 0.0 0.07 13.0 0.0 1.8 1 0 0 1 1 1 0 Bromodomain AAA_25 PF13481.1 AEO57561.1 - 0.032 13.6 0.0 0.11 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 AEO57561.1 - 0.032 13.9 0.1 0.032 13.9 0.1 4.1 4 0 0 4 4 3 0 Part of AAA domain NACHT PF05729.7 AEO57561.1 - 0.032 13.8 0.4 0.23 11.1 0.1 2.6 2 2 0 2 2 2 0 NACHT domain Parvo_NS1 PF01057.12 AEO57561.1 - 0.036 12.9 0.0 0.19 10.5 0.0 1.9 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.6 AEO57561.1 - 0.039 13.5 0.0 0.36 10.4 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Torsin PF06309.6 AEO57561.1 - 0.065 13.1 0.0 1.7 8.5 0.0 2.3 2 0 0 2 2 2 0 Torsin Sigma54_activat PF00158.21 AEO57561.1 - 0.081 12.3 0.0 3.4 7.0 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain RNA_pol_I_A49 PF06870.7 AEO57562.1 - 1.1e-79 267.8 0.7 1.2e-79 267.6 0.5 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor NusA_N PF08529.6 AEO57562.1 - 0.021 14.8 0.1 0.053 13.5 0.1 1.7 1 1 0 1 1 1 0 NusA N-terminal domain Pkinase PF00069.20 AEO57564.1 - 6.3e-41 140.2 0.0 6.9e-41 140.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO57564.1 - 2.6e-19 69.3 0.0 3.1e-19 69.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 AEO57564.1 - 2.7e-05 23.3 0.0 3.7e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 AEO57564.1 - 8.5e-05 21.6 0.0 0.13 11.1 0.0 2.1 1 1 1 2 2 2 2 Kinase-like YrbL-PhoP_reg PF10707.4 AEO57564.1 - 0.015 14.6 0.0 0.019 14.3 0.0 1.1 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pkinase PF00069.20 AEO57565.1 - 0.027 13.6 0.0 0.035 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain BCNT PF07572.7 AEO57567.1 - 2.2e-24 85.1 2.6 4.6e-24 84.1 1.8 1.6 1 0 0 1 1 1 1 Bucentaur or craniofacial development WD40 PF00400.27 AEO57569.1 - 1.8e-24 84.6 9.4 1.1e-06 28.3 0.3 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 AEO57569.1 - 0.0029 17.3 0.0 0.25 11.0 0.0 3.3 3 2 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A TFIIF_alpha PF05793.7 AEO57569.1 - 0.35 9.1 8.6 0.35 9.1 3.5 2.0 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FAM176 PF14851.1 AEO57569.1 - 0.76 9.4 3.1 1.9 8.1 2.1 1.6 1 0 0 1 1 1 0 FAM176 family SNF2_N PF00176.18 AEO57570.1 - 1.8e-84 283.0 1.4 1.8e-84 283.0 1.0 2.1 3 0 0 3 3 3 1 SNF2 family N-terminal domain Bromodomain PF00439.20 AEO57570.1 - 6.2e-21 74.1 0.0 2e-20 72.4 0.0 1.9 1 0 0 1 1 1 1 Bromodomain SnAC PF14619.1 AEO57570.1 - 8.8e-18 64.2 0.4 8.8e-18 64.2 0.3 4.3 4 1 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex Helicase_C PF00271.26 AEO57570.1 - 1.6e-17 63.0 8.1 3e-17 62.2 0.0 4.2 5 0 0 5 5 5 1 Helicase conserved C-terminal domain HSA PF07529.8 AEO57570.1 - 1.1e-14 53.9 10.0 1.1e-14 53.9 7.0 3.9 4 0 0 4 4 4 1 HSA QLQ PF08880.6 AEO57570.1 - 2.4e-10 39.6 0.9 2.4e-10 39.6 0.7 2.6 3 0 0 3 3 3 1 QLQ P2 PF07194.6 AEO57570.1 - 0.07 12.9 0.1 0.97 9.3 0.0 2.4 2 0 0 2 2 2 0 P2 response regulator binding domain Zip PF02535.17 AEO57571.1 - 7.8e-36 123.6 22.6 5.6e-35 120.8 15.6 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter Endonuclease_NS PF01223.18 AEO57572.1 - 7.9e-63 211.8 0.0 9.7e-63 211.5 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Patatin PF01734.17 AEO57572.1 - 2.2 8.1 4.5 7.6 6.4 2.5 1.9 1 1 1 2 2 2 0 Patatin-like phospholipase WD40 PF00400.27 AEO57573.1 - 2.8e-46 153.7 24.3 2.9e-08 33.2 0.0 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 AEO57573.1 - 0.015 14.0 0.0 0.074 11.7 0.0 2.2 2 1 0 2 2 2 0 Nup133 N terminal like eIF2A PF08662.6 AEO57573.1 - 0.12 12.1 0.0 2.4 7.8 0.0 2.3 1 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A MBOAT PF03062.14 AEO57574.1 - 2e-21 76.4 20.6 3.1e-21 75.8 14.3 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 AEO57574.1 - 0.00012 22.0 5.5 0.00034 20.6 3.8 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family ICMT PF04140.9 AEO57575.1 - 2.7e-27 94.8 0.5 2.7e-27 94.8 0.3 1.6 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 AEO57575.1 - 1.9e-13 50.4 2.6 1.9e-13 50.4 1.8 2.1 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 AEO57575.1 - 0.0013 18.0 0.4 0.0022 17.3 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Tmemb_170 PF10190.4 AEO57576.1 - 0.026 14.5 5.5 0.032 14.2 3.8 1.1 1 0 0 1 1 1 0 Putative transmembrane protein 170 DUF4118 PF13493.1 AEO57576.1 - 3.5 7.8 16.7 5.3 7.2 10.7 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4118) DUF3446 PF11928.3 AEO57577.1 - 9.2 6.5 21.2 6.4 7.0 6.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) zf-C2H2 PF00096.21 AEO57578.1 - 6.1e-17 60.8 22.9 0.00011 22.3 0.1 7.5 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AEO57578.1 - 1.6e-12 46.8 23.8 0.014 15.6 0.3 7.3 7 0 0 7 7 7 4 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AEO57578.1 - 0.00016 21.8 19.6 6.7 7.2 0.0 8.4 8 2 0 8 8 8 1 Zinc-finger double domain DUF4187 PF13821.1 AEO57578.1 - 0.0014 18.1 0.3 0.01 15.4 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) zf-TRAF PF02176.13 AEO57578.1 - 0.0025 18.1 9.7 2.7 8.4 0.1 4.7 4 0 0 4 4 4 1 TRAF-type zinc finger zf-C2H2_jaz PF12171.3 AEO57578.1 - 0.012 15.7 13.4 1.2 9.3 0.1 6.4 7 0 0 7 7 7 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 AEO57578.1 - 0.013 15.7 11.6 0.79 10.0 0.1 5.4 7 0 0 7 7 7 0 Zinc-finger of C2H2 type Ogr_Delta PF04606.7 AEO57578.1 - 0.023 14.3 0.3 1.7 8.3 0.0 3.3 2 1 1 3 3 3 0 Ogr/Delta-like zinc finger zf-Di19 PF05605.7 AEO57578.1 - 0.055 13.5 18.3 7 6.8 0.0 6.2 4 1 3 7 7 7 0 Drought induced 19 protein (Di19), zinc-binding DUF1644 PF07800.7 AEO57578.1 - 0.094 12.5 11.4 0.13 12.0 0.0 4.5 3 2 2 5 5 5 0 Protein of unknown function (DUF1644) RNA_pol_Rpb6 PF01192.17 AEO57579.1 - 5.3e-23 80.5 0.2 9.1e-23 79.7 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb6 Nop14 PF04147.7 AEO57579.1 - 0.7 7.7 4.6 0.66 7.8 3.2 1.0 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.8 AEO57579.1 - 1.3 8.6 5.2 1.9 8.0 3.6 1.3 1 0 0 1 1 1 0 YL1 nuclear protein WSC PF01822.14 AEO57580.1 - 1.1e-30 105.3 21.9 2.7e-17 62.4 6.4 5.0 5 0 0 5 5 5 2 WSC domain PCI PF01399.22 AEO57581.1 - 6.1e-09 36.1 0.4 9.9e-08 32.2 0.0 3.0 2 0 0 2 2 2 1 PCI domain G-gamma PF00631.17 AEO57582.1 - 3.6e-28 97.1 0.0 4.4e-28 96.8 0.0 1.1 1 0 0 1 1 1 1 GGL domain Rdx PF10262.4 AEO57583.1 - 6.5e-29 99.7 0.0 8.5e-29 99.3 0.0 1.2 1 0 0 1 1 1 1 Rdx family Metallophos PF00149.23 AEO57584.1 - 1.2e-44 152.0 0.2 1.5e-44 151.8 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase zf-HC5HC2H_2 PF13832.1 AEO57585.1 - 8.2e-34 115.9 8.4 8.2e-34 115.9 5.8 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 AEO57585.1 - 3.2e-26 91.3 8.0 3.2e-26 91.3 5.5 2.8 3 0 0 3 3 3 1 PHD-like zinc-binding domain EPL1 PF10513.4 AEO57585.1 - 7.7e-19 68.4 0.1 7.7e-19 68.4 0.1 3.2 3 1 0 3 3 3 1 Enhancer of polycomb-like PHD_2 PF13831.1 AEO57585.1 - 3.2e-14 51.9 2.1 3.2e-14 51.9 1.4 2.4 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 AEO57585.1 - 5e-08 32.5 26.2 1.2e-07 31.2 6.8 2.7 2 0 0 2 2 2 2 PHD-finger zf-RING-like PF08746.6 AEO57585.1 - 6.3 6.8 25.6 0.12 12.4 6.3 2.8 2 0 0 2 2 2 0 RING-like domain LRR_4 PF12799.2 AEO57586.1 - 1.7e-16 59.3 8.6 3.9e-06 26.3 2.4 4.8 2 1 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AEO57586.1 - 5.9e-12 45.1 9.2 1.8e-09 37.1 2.1 3.1 1 1 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 AEO57586.1 - 1.6e-09 36.4 9.6 0.29 11.3 0.4 6.3 5 1 1 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 AEO57586.1 - 0.0046 16.9 11.7 8.5 7.0 0.0 5.8 6 0 0 6 6 6 1 Leucine rich repeat LRR_6 PF13516.1 AEO57586.1 - 0.024 14.6 4.7 66 4.0 0.0 5.1 4 1 1 5 5 5 0 Leucine Rich repeat Ebola_NP PF05505.7 AEO57586.1 - 0.28 9.2 1.7 0.43 8.5 1.2 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein Biotin_lipoyl PF00364.17 AEO57588.1 - 7e-21 73.6 1.0 1.3e-20 72.8 0.7 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 AEO57588.1 - 2.1e-07 30.4 0.5 1.3e-06 27.9 0.0 2.6 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 AEO57588.1 - 3.8e-05 23.2 0.2 0.00057 19.4 0.1 2.6 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.1 AEO57588.1 - 0.024 14.9 1.2 3.4 8.0 0.0 2.8 2 1 1 3 3 3 0 HlyD family secretion protein HlyD_2 PF12700.2 AEO57588.1 - 0.056 12.5 0.5 1.7 7.7 0.0 2.1 1 1 1 2 2 2 0 HlyD family secretion protein QRPTase_N PF02749.11 AEO57588.1 - 0.072 12.9 0.0 0.24 11.2 0.0 2.0 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain CoA_transf_3 PF02515.12 AEO57589.1 - 5.6e-26 90.9 1.9 3.2e-25 88.4 0.6 2.1 2 0 0 2 2 2 1 CoA-transferase family III UPF0262 PF06793.7 AEO57589.1 - 0.17 11.6 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0262) Nop14 PF04147.7 AEO57589.1 - 0.5 8.2 4.5 0.61 7.9 3.1 1.1 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 AEO57589.1 - 4.4 6.8 13.9 7.6 6.0 9.6 1.4 1 0 0 1 1 1 0 Nucleoplasmin Fungal_trans PF04082.13 AEO57591.1 - 1.7e-28 99.2 0.1 3.7e-28 98.1 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Spore_YabQ PF09578.5 AEO57591.1 - 0.00076 19.3 0.1 0.0032 17.3 0.1 2.0 1 0 0 1 1 1 1 Spore cortex protein YabQ (Spore_YabQ) Dioxygenase_C PF00775.16 AEO57592.1 - 1.2e-52 177.8 0.0 1.8e-52 177.2 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase CarboxypepD_reg PF13620.1 AEO57592.1 - 5.9e-06 26.2 0.0 0.00032 20.6 0.0 2.4 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain DUF4198 PF10670.4 AEO57592.1 - 0.018 15.0 0.0 0.026 14.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) OPT PF03169.10 AEO57594.1 - 5.6e-192 639.4 48.7 6.4e-192 639.2 33.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4191 PF13829.1 AEO57594.1 - 0.37 9.8 1.6 1.2 8.2 1.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) ketoacyl-synt PF00109.21 AEO57595.1 - 2e-55 188.0 12.2 3e-53 180.9 4.7 3.0 2 1 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 AEO57595.1 - 3.1e-34 117.3 1.0 3.1e-34 117.3 0.7 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 AEO57595.1 - 2.2e-05 23.5 0.1 9e-05 21.5 0.0 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 AEO57595.1 - 0.042 13.2 3.6 0.12 11.7 0.2 3.1 2 2 0 2 2 2 0 Thiolase, C-terminal domain Ubiq_cyt_C_chap PF03981.7 AEO57596.1 - 1.2e-36 125.7 3.4 1.6e-36 125.2 2.4 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone DHFR_1 PF00186.14 AEO57597.1 - 3.6e-31 107.9 0.0 7e-24 84.2 0.0 2.6 2 1 0 2 2 2 2 Dihydrofolate reductase BAF1_ABF1 PF04684.8 AEO57597.1 - 0.0025 16.7 13.6 0.0025 16.7 9.4 2.1 2 0 0 2 2 2 1 BAF1 / ABF1 chromatin reorganising factor YdfA_immunity PF12127.3 AEO57597.1 - 0.009 14.9 0.3 0.012 14.4 0.2 1.1 1 0 0 1 1 1 1 SigmaW regulon antibacterial Pex14_N PF04695.8 AEO57597.1 - 0.13 12.3 6.7 0.21 11.6 4.6 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region US2 PF02476.10 AEO57597.1 - 0.67 10.4 4.1 1.3 9.5 0.1 2.3 2 0 0 2 2 2 0 US2 family PAT1 PF09770.4 AEO57597.1 - 1.1 7.4 20.2 1.4 7.0 14.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RIC3 PF15361.1 AEO57597.1 - 2.9 8.1 7.8 5.3 7.2 5.4 1.4 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Zip PF02535.17 AEO57597.1 - 3.9 6.3 4.6 5.4 5.9 3.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter TPR_1 PF00515.23 AEO57598.1 - 9.2e-11 40.8 8.1 0.0019 17.7 0.0 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 AEO57598.1 - 1.7e-10 40.4 2.9 0.046 13.3 0.0 5.6 4 1 1 5 5 5 3 TPR repeat TPR_14 PF13428.1 AEO57598.1 - 1.2e-09 37.8 24.7 0.021 15.4 0.1 7.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.12 AEO57598.1 - 6.2e-09 35.1 25.6 0.0048 16.7 0.0 7.1 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 AEO57598.1 - 3.4e-06 26.8 1.1 0.028 14.6 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 AEO57598.1 - 8.5e-06 25.6 9.3 7.2 6.6 0.0 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 AEO57598.1 - 1.1e-05 24.9 1.1 0.01 15.5 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 AEO57598.1 - 0.0019 18.7 27.0 0.46 11.2 0.0 6.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 AEO57598.1 - 0.0022 18.3 8.8 0.059 13.7 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 AEO57598.1 - 0.0035 17.0 4.9 8.4 6.4 0.1 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.1 AEO57598.1 - 0.018 14.8 5.2 4.2 7.2 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 AEO57598.1 - 0.1 13.0 12.6 2.5 8.7 0.2 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_21 PF09976.4 AEO57598.1 - 0.39 10.6 4.8 12 5.8 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat RIX1 PF08167.7 AEO57599.1 - 2.1e-46 157.5 0.7 8.6e-46 155.6 0.0 2.1 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis Glyco_hydro_16 PF00722.16 AEO57601.1 - 1.2e-09 37.6 0.4 2.1e-09 36.9 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Fungal_lectin PF07938.7 AEO57602.1 - 1.5e-09 37.6 0.3 0.0013 18.0 0.0 3.1 1 1 2 3 3 3 3 Fungal fucose-specific lectin Dus PF01207.12 AEO57603.1 - 1e-61 208.5 0.0 1.8e-61 207.6 0.0 1.4 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.16 AEO57603.1 - 0.0049 15.8 0.0 0.0085 15.0 0.0 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase CBP4 PF07960.6 AEO57603.1 - 0.43 10.2 2.9 1.6 8.3 1.1 2.2 2 0 0 2 2 2 0 CBP4 CRS1_YhbY PF01985.16 AEO57603.1 - 0.65 10.0 3.0 20 5.2 0.2 2.5 2 0 0 2 2 2 0 CRS1 / YhbY (CRM) domain MIF4G PF02854.14 AEO57605.1 - 7.6e-25 87.5 0.4 1.5e-24 86.6 0.3 1.5 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.12 AEO57605.1 - 1.6e-22 79.3 0.1 3.8e-22 78.1 0.0 1.7 2 0 0 2 2 2 1 MA3 domain Nop14 PF04147.7 AEO57605.1 - 0.017 13.0 8.8 0.024 12.5 6.1 1.1 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.1 AEO57605.1 - 0.42 10.2 8.7 0.83 9.3 6.0 1.4 1 0 0 1 1 1 0 FAM176 family CENP-B_dimeris PF09026.5 AEO57605.1 - 0.81 9.9 13.4 0.75 10.0 7.5 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 AEO57605.1 - 5 6.6 15.8 8 5.9 11.0 1.3 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 AEO57605.1 - 6.3 5.9 11.9 10 5.2 8.2 1.2 1 0 0 1 1 1 0 NOA36 protein TRAP_alpha PF03896.11 AEO57605.1 - 7.9 5.3 8.2 17 4.2 5.7 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DPM2 PF07297.7 AEO57606.1 - 3e-36 123.5 2.8 3.5e-36 123.3 1.9 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 AEO57606.1 - 4.5e-05 23.0 1.1 5.1e-05 22.8 0.7 1.1 1 0 0 1 1 1 1 PIG-P DUF4229 PF14012.1 AEO57606.1 - 0.0004 20.2 0.7 0.0004 20.2 0.5 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4229) COX14 PF14880.1 AEO57606.1 - 0.0028 17.2 1.3 0.038 13.5 0.0 2.1 2 0 0 2 2 2 1 Cytochrome oxidase c assembly DUF4083 PF13314.1 AEO57606.1 - 0.013 15.2 0.1 0.013 15.2 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) DiS_P_DiS PF06750.8 AEO57606.1 - 0.099 12.4 0.4 0.17 11.6 0.0 1.6 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain DUF1049 PF06305.6 AEO57606.1 - 0.12 11.8 0.2 0.12 11.8 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DUF1469 PF07332.6 AEO57606.1 - 0.2 11.3 2.8 0.26 11.0 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) TPPK_C PF12555.3 AEO57606.1 - 1.3 8.8 8.5 1.5 8.5 0.8 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal Herpes_UL43 PF05072.8 AEO57606.1 - 1.6 7.4 5.3 0.11 11.2 0.5 1.3 2 0 0 2 2 2 0 Herpesvirus UL43 protein PspC PF04024.7 AEO57606.1 - 6.3 6.3 6.1 19 4.8 1.0 2.1 2 0 0 2 2 2 0 PspC domain SnoaL_4 PF13577.1 AEO57608.1 - 0.00084 19.2 0.5 0.0026 17.6 0.3 1.8 1 1 0 1 1 1 1 SnoaL-like domain DdrB PF12747.2 AEO57608.1 - 0.027 14.1 0.1 0.037 13.7 0.1 1.2 1 0 0 1 1 1 0 DdrB-like protein DUF730 PF05325.6 AEO57608.1 - 0.038 13.7 0.5 0.15 11.8 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF730) ING PF12998.2 AEO57609.1 - 0.0039 17.4 3.3 0.02 15.1 0.0 3.0 2 1 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding DUF3138 PF11336.3 AEO57609.1 - 8.9 4.3 9.1 15 3.5 6.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) MinC_C PF03775.11 AEO57610.1 - 0.005 16.4 0.2 0.3 10.7 0.1 2.1 1 1 1 2 2 2 2 Septum formation inhibitor MinC, C-terminal domain Bactofilin PF04519.8 AEO57610.1 - 0.01 15.8 0.2 0.045 13.7 0.1 1.9 1 1 0 1 1 1 0 Polymer-forming cytoskeletal DUF342 PF03961.8 AEO57610.1 - 0.038 12.4 0.5 0.062 11.6 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) zf-C2H2 PF00096.21 AEO57612.1 - 0.017 15.4 3.4 0.043 14.1 2.3 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AEO57612.1 - 0.033 14.5 2.9 0.078 13.3 2.0 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AEO57612.1 - 0.11 12.8 2.3 12 6.3 0.3 2.4 2 0 0 2 2 2 0 Zinc-finger double domain DUF3602 PF12223.3 AEO57613.1 - 6e-10 39.3 15.8 0.0011 19.3 2.0 3.2 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) DnaJ PF00226.26 AEO57614.1 - 3e-07 30.0 0.0 5.1e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 AEO57614.1 - 1.7e-06 27.8 0.1 2.5e-06 27.2 0.1 1.5 1 1 0 1 1 1 1 Pam16 TMP_2 PF06791.8 AEO57614.1 - 0.031 13.8 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 Prophage tail length tape measure protein DUF3918 PF13056.1 AEO57614.1 - 0.2 10.9 4.1 0.11 11.8 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3918) Ku PF02735.11 AEO57616.1 - 7.9e-25 87.4 0.0 1.4e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 AEO57616.1 - 1.3e-21 77.0 0.0 2.1e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_PK_bind PF08785.6 AEO57616.1 - 4.1e-15 55.7 0.0 9.5e-15 54.5 0.0 1.6 1 0 0 1 1 1 1 Ku C terminal domain like VWA_2 PF13519.1 AEO57616.1 - 5.7e-06 26.5 0.0 1.6e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 AEO57616.1 - 0.00039 20.1 0.1 0.00088 19.0 0.1 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF4149 PF13664.1 AEO57617.1 - 2.9e-25 88.2 1.1 9.9e-25 86.5 0.3 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) PHO4 PF01384.15 AEO57617.1 - 0.0096 14.6 0.1 0.011 14.4 0.0 1.1 1 0 0 1 1 1 1 Phosphate transporter family DUF2721 PF11026.3 AEO57617.1 - 0.049 13.2 0.8 0.076 12.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) DUF1295 PF06966.7 AEO57618.1 - 2.2e-40 138.4 6.1 2.9e-40 138.0 4.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PrgI PF12666.2 AEO57618.1 - 0.12 12.5 1.9 2.5 8.2 0.0 2.7 2 0 0 2 2 2 0 PrgI family protein Topoisom_bac PF01131.15 AEO57619.1 - 2.9e-93 312.8 0.0 4.4e-88 295.8 0.0 2.1 2 0 0 2 2 2 2 DNA topoisomerase Toprim PF01751.17 AEO57619.1 - 2.9e-20 72.1 0.0 5.4e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Stb3 PF10330.4 AEO57620.1 - 2.8e-38 129.4 0.0 4.3e-38 128.8 0.0 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein DUF3521 PF12035.3 AEO57620.1 - 0.11 12.3 0.1 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3521) SET PF00856.23 AEO57621.1 - 2.7e-06 27.7 0.4 0.005 17.1 0.2 2.9 2 1 1 3 3 3 2 SET domain DZR PF12773.2 AEO57621.1 - 0.013 15.3 5.7 0.013 15.3 3.9 2.9 3 0 0 3 3 3 0 Double zinc ribbon TPR_11 PF13414.1 AEO57621.1 - 0.015 14.8 0.6 7.3 6.3 0.8 2.5 2 0 0 2 2 2 0 TPR repeat mono-CXXC PF15626.1 AEO57621.1 - 0.1 12.5 3.0 0.4 10.6 2.1 2.0 1 0 0 1 1 1 0 single CXXC unit GFA PF04828.9 AEO57621.1 - 0.26 11.2 6.8 2.8 7.9 0.2 3.0 2 1 1 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme TPR_16 PF13432.1 AEO57621.1 - 0.29 11.8 5.0 1.2 9.9 3.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF164 PF02591.10 AEO57621.1 - 0.46 10.3 4.4 1.3 8.9 0.2 2.7 2 0 0 2 2 2 0 Putative zinc ribbon domain zf-MYND PF01753.13 AEO57621.1 - 1.7 8.5 11.7 0.12 12.2 3.7 2.4 2 0 0 2 2 2 0 MYND finger HypA PF01155.14 AEO57621.1 - 2.1 8.0 5.1 0.4 10.3 0.4 2.0 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Zn-ribbon_8 PF09723.5 AEO57621.1 - 4.5 7.3 8.8 0.3 11.0 1.5 2.3 2 0 0 2 2 2 0 Zinc ribbon domain Hydrolase_6 PF13344.1 AEO57622.1 - 9.8e-29 99.2 0.0 1.7e-28 98.4 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 AEO57622.1 - 1e-13 52.1 0.0 1.7e-13 51.5 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 AEO57622.1 - 2.1e-11 43.3 0.0 1.1e-10 41.0 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 AEO57622.1 - 4.3e-07 30.3 0.0 0.00011 22.5 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Ribosomal_L7Ae PF01248.21 AEO57622.1 - 0.15 11.5 0.0 0.4 10.2 0.0 1.6 2 0 0 2 2 2 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Glucosamine_iso PF01182.15 AEO57623.1 - 2.7e-61 206.7 0.0 3.2e-61 206.5 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Glyco_hydro_76 PF03663.9 AEO57624.1 - 3e-55 188.1 4.1 3.7e-55 187.8 2.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 DUF1680 PF07944.7 AEO57624.1 - 3.4e-05 22.3 0.3 0.079 11.2 0.1 3.1 1 1 0 3 3 3 2 Putative glycosyl hydrolase of unknown function (DUF1680) Glyco_hydro_88 PF07470.8 AEO57624.1 - 0.00023 20.3 3.5 0.25 10.3 0.0 3.0 1 1 1 3 3 3 2 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.8 AEO57624.1 - 0.0026 17.0 2.5 2.5 7.3 0.0 3.6 3 1 1 4 4 4 2 D-glucuronyl C5-epimerase C-terminus Pectate_lyase_2 PF06917.7 AEO57624.1 - 0.0052 15.0 0.1 0.72 8.0 0.0 2.1 1 1 1 2 2 2 2 Periplasmic pectate lyase C1_3 PF07649.7 AEO57625.1 - 5.5 7.1 11.4 8.5 6.5 7.9 1.3 1 0 0 1 1 1 0 C1-like domain Tim54 PF11711.3 AEO57626.1 - 6.7 5.1 15.8 3.3 6.2 0.7 2.3 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 zf-C2H2 PF00096.21 AEO57627.1 - 1.6e-06 28.0 21.5 1.5e-05 25.0 2.6 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 AEO57627.1 - 2.6e-05 24.2 3.8 2.6e-05 24.2 2.7 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 AEO57627.1 - 0.00034 20.6 1.0 0.00088 19.3 0.7 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 AEO57627.1 - 0.00053 20.1 0.9 0.00053 20.1 0.6 3.8 3 0 0 3 3 3 1 C2H2-type zinc finger zf-met PF12874.2 AEO57627.1 - 0.1 12.8 0.8 0.31 11.3 0.5 1.8 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-TRAF PF02176.13 AEO57627.1 - 0.87 10.0 8.9 0.18 12.1 2.2 2.3 2 0 0 2 2 2 0 TRAF-type zinc finger zf-RING_2 PF13639.1 AEO57628.1 - 0.018 14.8 9.3 0.041 13.7 3.8 2.9 2 1 0 2 2 2 0 Ring finger domain zf-rbx1 PF12678.2 AEO57628.1 - 0.095 12.8 7.6 0.029 14.4 3.1 1.8 2 0 0 2 2 2 0 RING-H2 zinc finger zf-C2H2_jaz PF12171.3 AEO57628.1 - 0.29 11.3 0.0 0.29 11.3 0.0 2.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C3HC4_2 PF13923.1 AEO57628.1 - 1.6 8.7 11.8 0.074 13.0 1.2 3.1 2 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DUF2361 PF10153.4 AEO57629.1 - 1.3e-36 125.2 10.3 1.3e-36 125.2 7.1 2.4 2 1 0 2 2 2 1 Uncharacterised conserved protein (DUF2361) PTS_2-RNA PF01885.11 AEO57631.1 - 2.3e-64 216.1 0.0 3.5e-64 215.5 0.0 1.2 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family DSPc PF00782.15 AEO57633.1 - 2.5e-24 85.3 0.1 2.4e-22 78.9 0.0 2.2 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 AEO57633.1 - 0.0013 18.1 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 AEO57633.1 - 0.12 11.1 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase UAA PF08449.6 AEO57634.1 - 4.1e-71 239.3 3.3 9.8e-71 238.1 2.3 1.5 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 AEO57634.1 - 4.4e-10 39.6 26.8 6.8e-06 26.1 3.1 3.5 4 0 0 4 4 4 3 EamA-like transporter family Nuc_sug_transp PF04142.10 AEO57634.1 - 4.5e-06 25.9 3.7 0.026 13.6 0.3 2.3 2 0 0 2 2 2 2 Nucleotide-sugar transporter TPT PF03151.11 AEO57634.1 - 1.1e-05 25.0 4.9 1.1e-05 25.0 3.4 3.0 2 1 0 2 2 2 1 Triose-phosphate Transporter family EmrE PF13536.1 AEO57634.1 - 9e-05 22.6 23.5 0.00025 21.2 4.1 3.3 3 1 0 3 3 3 2 Multidrug resistance efflux transporter PsaX PF08078.7 AEO57634.1 - 0.0046 16.8 0.0 0.024 14.5 0.0 2.3 2 0 0 2 2 2 1 PsaX family KH_1 PF00013.24 AEO57635.1 - 2e-38 129.8 11.4 1.5e-14 53.3 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 AEO57635.1 - 3.8e-29 99.8 12.4 6e-11 41.7 0.6 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 AEO57635.1 - 4.3e-10 38.9 9.8 0.004 16.6 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 AEO57635.1 - 2.3e-08 33.5 3.9 0.052 13.1 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 AEO57635.1 - 0.00097 18.8 4.6 0.64 9.8 0.0 3.3 3 0 0 3 3 3 2 NusA-like KH domain dUTPase PF00692.14 AEO57635.1 - 0.024 14.0 0.2 1.6 8.1 0.0 2.9 3 0 0 3 3 3 0 dUTPase F-box-like PF12937.2 AEO57636.1 - 2e-08 33.8 0.3 7.4e-08 31.9 0.2 2.1 2 0 0 2 2 2 1 F-box-like LRR_6 PF13516.1 AEO57636.1 - 5.2e-08 32.1 0.4 0.56 10.4 0.0 7.0 8 0 0 8 8 8 1 Leucine Rich repeat LRR_4 PF12799.2 AEO57636.1 - 1.9e-07 30.5 2.3 0.23 11.1 0.0 5.5 5 1 1 6 6 6 2 Leucine Rich repeats (2 copies) F-box PF00646.28 AEO57636.1 - 9.2e-06 25.1 2.1 1.1e-05 24.9 0.2 2.1 2 0 0 2 2 2 1 F-box domain LRR_1 PF00560.28 AEO57636.1 - 6.4e-05 22.4 9.9 0.8 9.9 0.0 6.6 8 1 0 8 8 8 2 Leucine Rich Repeat PRANC PF09372.5 AEO57636.1 - 0.29 11.1 0.0 0.77 9.7 0.0 1.7 1 0 0 1 1 1 0 PRANC domain LRR_7 PF13504.1 AEO57636.1 - 1.8 9.1 12.5 42 4.9 0.1 6.6 7 0 0 7 7 7 0 Leucine rich repeat Pkinase PF00069.20 AEO57638.1 - 1.2e-58 198.3 0.0 1.6e-58 197.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO57638.1 - 6.8e-20 71.2 0.0 1.1e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO57638.1 - 3.2e-09 36.1 0.0 5.3e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AEO57638.1 - 9.8e-05 22.1 0.4 0.00081 19.1 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 AEO57638.1 - 0.0015 17.5 0.0 0.0031 16.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 AEO57638.1 - 0.0032 16.8 0.1 0.0067 15.7 0.1 1.5 1 0 0 1 1 1 1 RIO1 family PAS_9 PF13426.1 AEO57638.1 - 0.015 15.6 0.0 0.71 10.2 0.0 2.9 2 1 0 2 2 2 0 PAS domain STE3 PF02076.10 AEO57639.1 - 8.9e-42 143.1 12.2 1.1e-41 142.7 8.5 1.1 1 0 0 1 1 1 1 Pheromone A receptor DUF3275 PF11679.3 AEO57639.1 - 1.4 8.5 6.1 3.5 7.1 1.6 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3275) DUF3671 PF12420.3 AEO57639.1 - 3.9 7.4 5.0 1.2 9.1 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF912 PF06024.7 AEO57639.1 - 6.5 6.8 7.5 3.6 7.7 0.1 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) SSB PF00436.20 AEO57640.1 - 1e-17 63.8 0.0 1.2e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family GIDA PF01134.17 AEO57641.1 - 1.2e-157 524.7 0.0 1.5e-157 524.5 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 AEO57641.1 - 1.9e-18 66.2 0.0 2.4e-17 62.7 0.0 2.6 2 0 0 2 2 2 1 GidA associated domain 3 FAD_oxidored PF12831.2 AEO57641.1 - 1.4e-06 27.6 0.3 2.2e-06 27.0 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 AEO57641.1 - 4.2e-06 26.7 0.2 9.6e-06 25.6 0.2 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 AEO57641.1 - 6.7e-05 21.9 2.0 0.16 10.7 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 AEO57641.1 - 0.0014 17.5 2.6 0.0014 17.5 1.8 2.6 4 0 0 4 4 4 1 FAD binding domain AlaDh_PNT_C PF01262.16 AEO57641.1 - 0.0024 17.4 0.2 0.0045 16.5 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 AEO57641.1 - 0.0084 14.6 1.3 0.15 10.5 0.7 2.2 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 AEO57641.1 - 0.085 13.2 0.3 0.32 11.4 0.3 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 AEO57641.1 - 0.089 13.0 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding CDP-OH_P_transf PF01066.16 AEO57642.1 - 8.6e-17 61.2 5.3 1.6e-16 60.4 3.7 1.4 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Gti1_Pac2 PF09729.4 AEO57643.1 - 1.1e-06 28.6 0.0 1.4e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Gti1/Pac2 family Tyr-DNA_phospho PF06087.7 AEO57644.1 - 5.9e-70 236.1 0.0 7.7e-70 235.7 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 AEO57644.1 - 0.0006 19.5 0.0 0.039 13.7 0.0 2.4 2 0 0 2 2 2 1 PLD-like domain UIM PF02809.15 AEO57644.1 - 0.07 12.7 0.3 0.07 12.7 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin interaction motif PNRC PF15365.1 AEO57645.1 - 1.4e-06 28.2 12.2 3.8e-05 23.6 4.0 4.3 3 1 0 3 3 3 2 Proline-rich nuclear receptor coactivator zf-rbx1 PF12678.2 AEO57646.1 - 4e-35 119.7 13.5 5e-35 119.4 9.4 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 AEO57646.1 - 4e-17 61.8 9.8 5.2e-17 61.4 6.8 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 AEO57646.1 - 4.8e-07 29.5 11.8 3.1e-06 26.9 8.1 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 AEO57646.1 - 0.0014 18.2 11.6 0.025 14.2 8.0 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AEO57646.1 - 0.0034 17.0 9.7 0.43 10.3 6.9 2.4 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AEO57646.1 - 0.049 13.6 12.5 0.053 13.5 5.4 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO57646.1 - 0.55 9.9 11.8 5.3 6.8 8.2 2.4 1 1 1 2 2 2 0 zinc-RING finger domain FANCL_C PF11793.3 AEO57646.1 - 0.88 9.5 9.3 4.8 7.2 6.6 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 AEO57646.1 - 1.8 8.3 7.0 4.1 7.2 2.4 2.2 1 1 1 2 2 2 0 RING-type zinc-finger zf-HC5HC2H PF13771.1 AEO57646.1 - 1.9 8.7 10.9 89 3.3 7.1 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain SPC12 PF06645.8 AEO57647.1 - 1.6e-29 101.5 0.5 1.9e-29 101.2 0.4 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) MerC PF03203.9 AEO57647.1 - 0.011 16.1 0.1 0.011 16.0 0.1 1.1 1 0 0 1 1 1 0 MerC mercury resistance protein ZYG-11_interact PF05884.7 AEO57647.1 - 0.05 12.7 0.1 0.054 12.5 0.1 1.0 1 0 0 1 1 1 0 Interactor of ZYG-11 CorA PF01544.13 AEO57648.1 - 4e-43 147.5 0.0 5.7e-43 147.0 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein zf-Tim10_DDP PF02953.10 AEO57649.1 - 6.1e-22 76.6 2.2 7.8e-22 76.3 1.5 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Spore_III_AB PF09548.5 AEO57649.1 - 0.022 14.5 0.2 0.025 14.3 0.1 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) CDI PF02234.14 AEO57649.1 - 0.17 11.6 1.0 0.54 10.1 0.4 1.9 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor Ribosomal_L23eN PF03939.8 AEO57650.1 - 9.3e-21 73.6 11.3 9.3e-21 73.6 7.8 2.4 2 1 1 3 3 3 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 AEO57650.1 - 1.3e-15 57.0 1.1 1.3e-15 57.0 0.8 1.8 2 1 1 3 3 3 1 Ribosomal protein L23 P2 PF07194.6 AEO57650.1 - 0.12 12.2 0.2 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 P2 response regulator binding domain DUF3321 PF11968.3 AEO57651.1 - 2.5e-94 315.0 0.0 3.1e-94 314.7 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) HAD_2 PF13419.1 AEO57652.1 - 7.4e-28 97.9 0.0 8.9e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 AEO57652.1 - 0.0029 17.2 0.0 0.0053 16.4 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Acid_PPase PF12689.2 AEO57652.1 - 0.16 11.6 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Acid Phosphatase Pkinase PF00069.20 AEO57653.1 - 1.9e-58 197.6 0.0 2.9e-58 197.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO57653.1 - 5.4e-32 110.8 0.0 8e-32 110.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO57653.1 - 5.2e-13 48.5 0.0 3.4e-10 39.3 0.0 2.8 2 1 1 3 3 3 2 Kinase-like Kdo PF06293.9 AEO57653.1 - 0.0025 16.9 0.0 0.0057 15.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4619 PF15398.1 AEO57653.1 - 0.038 13.4 1.0 0.065 12.6 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4619) DLL_N PF12413.3 AEO57653.1 - 0.28 12.2 6.5 0.09 13.8 1.9 2.0 2 0 0 2 2 2 0 Homeobox protein distal-less-like N terminal Aa_trans PF01490.13 AEO57654.1 - 5e-61 206.4 26.1 6.1e-61 206.1 18.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DEAD PF00270.24 AEO57655.1 - 1.1e-32 112.8 0.0 2.2e-32 111.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO57655.1 - 4.4e-17 61.7 0.0 8.9e-17 60.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AEO57655.1 - 6.6e-05 22.8 0.0 0.00013 21.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 AEO57655.1 - 0.00081 18.2 0.0 0.0011 17.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain CorA PF01544.13 AEO57656.1 - 1e-05 24.7 0.0 1e-05 24.7 0.0 1.7 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF2029 PF09594.5 AEO57656.1 - 0.07 12.6 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2029) DUF4448 PF14610.1 AEO57656.1 - 0.11 11.9 0.0 1.2 8.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) Pkinase PF00069.20 AEO57657.1 - 3.2e-71 239.5 1.9 1.2e-70 237.6 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO57657.1 - 4.5e-38 130.7 0.6 1.7e-37 128.9 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO57657.1 - 4.9e-08 32.2 0.0 1.1e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Spore_coat_CotO PF14153.1 AEO57657.1 - 0.18 11.2 31.5 0.2 11.0 9.6 2.2 2 0 0 2 2 2 0 Spore coat protein CotO Med15 PF09606.5 AEO57657.1 - 1 7.4 75.4 1.4 6.9 52.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal BAF1_ABF1 PF04684.8 AEO57657.1 - 7.7 5.2 53.3 0.22 10.3 22.4 2.3 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor DUF1510 PF07423.6 AEO57657.1 - 9.8 5.4 26.8 5.6 6.2 4.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Lectin_leg-like PF03388.8 AEO57658.1 - 7.1e-67 224.9 0.0 9.2e-67 224.5 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 AEO57658.1 - 0.0089 15.4 0.0 0.41 9.9 0.0 2.2 2 0 0 2 2 2 2 Legume lectin domain zf-Tim10_DDP PF02953.10 AEO57659.1 - 1.3e-21 75.5 0.6 1.8e-21 75.2 0.4 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF2040 PF09745.4 AEO57660.1 - 6.5e-39 132.6 16.5 6.5e-39 132.6 11.5 4.2 4 1 0 4 4 4 1 Coiled-coil domain-containing protein 55 (DUF2040) PI-PLC-X PF00388.14 AEO57661.1 - 1.3e-63 212.8 0.0 1.9e-63 212.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 AEO57661.1 - 8.4e-40 135.4 0.0 1.5e-39 134.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 AEO57661.1 - 0.0033 17.2 0.0 0.031 14.1 0.0 2.4 2 0 0 2 2 2 1 C2 domain SR-25 PF10500.4 AEO57661.1 - 0.014 14.9 2.9 0.029 13.8 2.0 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Dehydrin PF00257.14 AEO57661.1 - 6.4 7.0 9.5 1 9.7 3.5 1.9 2 1 0 2 2 2 0 Dehydrin HTH_psq PF05225.11 AEO57662.1 - 3e-11 42.6 0.0 5e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_23 PF13384.1 AEO57662.1 - 0.0056 16.2 0.0 0.0074 15.9 0.0 1.4 1 1 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 AEO57662.1 - 0.029 14.3 0.0 0.041 13.8 0.0 1.4 1 1 0 1 1 1 0 Helix-turn-helix domain NUMOD1 PF07453.8 AEO57662.1 - 0.055 13.3 0.1 0.28 11.1 0.0 1.9 2 0 0 2 2 2 0 NUMOD1 domain CENP-B_N PF04218.8 AEO57662.1 - 0.057 12.8 0.1 0.81 9.1 0.0 2.1 1 1 1 2 2 2 0 CENP-B N-terminal DNA-binding domain MerR PF00376.18 AEO57662.1 - 0.089 12.3 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 MerR family regulatory protein HTH_3 PF01381.17 AEO57662.1 - 0.12 12.1 0.0 7.1 6.5 0.0 2.1 1 1 1 2 2 2 0 Helix-turn-helix Actin PF00022.14 AEO57663.1 - 8e-27 93.6 0.0 1.8e-17 62.9 0.0 2.8 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 AEO57663.1 - 0.0084 14.7 0.0 0.33 9.4 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein DUF4451 PF14616.1 AEO57665.1 - 3.1e-35 120.6 0.5 5.1e-35 119.9 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) Mucin PF01456.12 AEO57665.1 - 3.5 7.4 31.3 0.066 12.9 7.2 2.6 2 0 0 2 2 2 0 Mucin-like glycoprotein PHD PF00628.24 AEO57666.1 - 1.3e-08 34.3 5.3 2.1e-08 33.6 3.7 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 AEO57666.1 - 0.0077 15.5 2.5 0.013 14.7 1.7 1.4 1 0 0 1 1 1 1 PHD-finger Iso_dh PF00180.15 AEO57667.1 - 2.1e-130 434.7 0.0 2.4e-130 434.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase SR-25 PF10500.4 AEO57668.1 - 3.4 7.0 18.2 7.2 6.0 12.6 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1762 PF08574.5 AEO57670.1 - 1.3e-08 35.1 7.9 1.3e-08 35.1 5.5 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1762) Fungal_trans PF04082.13 AEO57671.1 - 2.6e-05 23.2 0.0 3.4e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain His_Phos_1 PF00300.17 AEO57673.1 - 1.2e-23 83.9 0.0 1.8e-23 83.3 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) RabGAP-TBC PF00566.13 AEO57675.1 - 2e-24 86.2 0.0 3.2e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PBD PF00786.23 AEO57676.1 - 0.01 16.2 3.7 0.024 15.0 0.0 3.3 3 0 0 3 3 3 0 P21-Rho-binding domain Histone PF00125.19 AEO57677.1 - 9.3e-29 99.3 0.4 1.4e-28 98.8 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 AEO57677.1 - 0.00027 21.0 0.0 0.0004 20.4 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 AEO57677.1 - 0.062 13.3 0.1 0.1 12.6 0.1 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DER1 PF04511.10 AEO57678.1 - 1.2e-50 171.8 5.1 1.3e-50 171.6 3.6 1.0 1 0 0 1 1 1 1 Der1-like family ARD PF03079.9 AEO57679.1 - 1.4e-44 151.8 0.0 1.6e-44 151.5 0.0 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 AEO57679.1 - 1.4e-09 37.3 0.1 2.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 AEO57679.1 - 6.2e-07 29.1 0.0 8.7e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 AEO57679.1 - 0.023 14.1 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 Cupin adh_short PF00106.20 AEO57680.1 - 3.4e-20 72.6 0.0 4.9e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO57680.1 - 4.9e-12 45.8 0.0 7.8e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 AEO57680.1 - 8.4e-08 31.9 0.0 1.5e-07 31.1 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 AEO57680.1 - 0.00044 20.3 0.0 0.0011 18.9 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 AEO57680.1 - 0.002 16.8 0.0 0.0031 16.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 AEO57680.1 - 0.0062 15.4 0.0 0.012 14.5 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.8 AEO57680.1 - 0.028 13.6 0.0 0.064 12.5 0.0 1.6 2 0 0 2 2 2 0 NmrA-like family SAPS PF04499.10 AEO57680.1 - 0.037 12.6 0.5 0.054 12.1 0.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein F420_oxidored PF03807.12 AEO57680.1 - 0.096 13.1 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pox_Ag35 PF03286.9 AEO57680.1 - 0.23 10.9 14.4 0.33 10.4 10.0 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein UAA PF08449.6 AEO57681.1 - 1.3e-10 40.7 10.0 2.2e-10 39.9 6.9 1.3 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 AEO57681.1 - 2.8e-08 33.5 3.4 2.8e-08 33.5 2.4 2.5 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 AEO57681.1 - 0.0021 18.1 26.3 0.15 12.0 8.1 2.2 2 0 0 2 2 2 2 EamA-like transporter family Abi PF02517.11 AEO57682.1 - 8.2e-13 48.3 6.6 8.2e-13 48.3 4.5 2.6 2 1 1 3 3 3 1 CAAX protease self-immunity DUF1639 PF07797.9 AEO57683.1 - 5.6 6.4 8.1 0.5 9.8 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1639) MBOAT PF03062.14 AEO57684.1 - 1e-51 175.9 2.1 1e-51 175.9 1.4 1.5 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family PAP2 PF01569.16 AEO57684.1 - 0.089 12.4 6.9 0.047 13.3 2.5 2.3 2 0 0 2 2 2 0 PAP2 superfamily DUF2404 PF10296.4 AEO57686.1 - 7e-08 32.5 0.0 2.6e-07 30.6 0.0 2.0 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) Sec1 PF00995.18 AEO57687.1 - 1.1e-154 516.2 0.0 1.2e-154 516.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family B12-binding PF02310.14 AEO57687.1 - 0.082 12.7 0.3 0.24 11.2 0.2 1.8 1 0 0 1 1 1 0 B12 binding domain GSH_synth_ATP PF03917.12 AEO57688.1 - 3.6e-111 371.3 0.0 4.5e-111 371.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 AEO57688.1 - 1.9e-32 111.4 0.0 3.2e-32 110.7 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase SNF2_N PF00176.18 AEO57689.1 - 1.2e-44 152.2 0.1 2.2e-44 151.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AEO57689.1 - 2.8e-12 46.3 0.1 9.7e-12 44.5 0.1 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TFIIS_M PF07500.9 AEO57689.1 - 0.031 14.3 0.2 0.031 14.3 0.2 2.6 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS), central domain Aminotran_1_2 PF00155.16 AEO57690.1 - 1.9e-85 287.0 0.1 2.9e-85 286.4 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class I and II Aminotran_5 PF00266.14 AEO57690.1 - 2.5e-06 26.5 0.0 6.8e-06 25.0 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 AEO57690.1 - 1.1e-05 23.8 0.0 1.8e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 AEO57690.1 - 0.009 15.0 0.2 0.026 13.5 0.1 1.7 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Zn_clus PF00172.13 AEO57691.1 - 0.00049 19.9 11.9 0.00088 19.1 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lyase_1 PF00206.15 AEO57692.1 - 9.8e-26 90.6 0.1 1.5e-25 90.0 0.1 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 AEO57692.1 - 6.5e-16 58.1 0.0 1.7e-15 56.7 0.0 1.8 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus DUF4089 PF13318.1 AEO57692.1 - 0.14 12.4 0.6 0.59 10.4 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4089) Glyco_hydro_30 PF02055.11 AEO57693.1 - 1.3e-20 73.1 0.1 9.2e-20 70.3 0.1 2.0 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 AEO57693.1 - 1.6e-12 47.0 0.1 1.6e-12 47.0 0.0 1.9 2 0 0 2 2 2 1 O-Glycosyl hydrolase family 30 HK PF02110.10 AEO57694.1 - 2.2e-77 259.5 0.9 2.2e-77 259.5 0.6 1.7 2 0 0 2 2 2 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 AEO57694.1 - 8.4e-59 197.7 2.0 1.4e-58 196.9 1.4 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI Phos_pyr_kin PF08543.7 AEO57694.1 - 2.3e-05 23.7 0.1 5.6e-05 22.4 0.1 1.6 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Carb_kinase PF01256.12 AEO57694.1 - 2.9e-05 23.5 0.2 4.8e-05 22.7 0.2 1.5 1 0 0 1 1 1 1 Carbohydrate kinase ADH_zinc_N PF00107.21 AEO57694.1 - 0.0097 15.4 1.2 0.059 12.9 0.1 2.7 2 1 0 2 2 2 1 Zinc-binding dehydrogenase Isochorismatase PF00857.15 AEO57695.1 - 2.2e-25 89.5 0.6 7.5e-25 87.8 0.4 1.8 1 1 0 1 1 1 1 Isochorismatase family Lipase_GDSL_2 PF13472.1 AEO57697.1 - 8.4e-22 78.1 0.0 1.1e-21 77.8 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 AEO57697.1 - 5.4e-17 62.3 0.0 6.5e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 AEO57697.1 - 0.0018 18.0 0.2 0.028 14.1 0.0 2.1 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family LysM PF01476.15 AEO57698.1 - 0.0044 16.8 0.0 0.0096 15.8 0.0 1.5 1 0 0 1 1 1 1 LysM domain UBA_4 PF14555.1 AEO57698.1 - 0.032 13.7 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 UBA-like domain Baculo_IE-1 PF05290.6 AEO57698.1 - 0.56 9.9 3.1 0.93 9.2 2.2 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) CPSF_A PF03178.10 AEO57699.1 - 1.7e-100 336.2 0.0 7.7e-100 334.0 0.0 2.1 3 0 0 3 3 3 1 CPSF A subunit region MMS1_N PF10433.4 AEO57699.1 - 6.2e-65 219.2 0.0 1e-64 218.5 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term WD40 PF00400.27 AEO57699.1 - 0.054 13.3 0.1 0.19 11.6 0.1 2.0 1 0 0 1 1 1 0 WD domain, G-beta repeat zf-Mss51 PF13824.1 AEO57700.1 - 1.3e-27 95.3 8.0 3e-27 94.2 5.6 1.7 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 AEO57700.1 - 0.016 15.1 3.2 0.016 15.1 2.2 2.0 2 0 0 2 2 2 0 MYND finger GFA PF04828.9 AEO57700.1 - 0.22 11.4 0.9 0.52 10.2 0.1 1.9 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme PXA PF02194.10 AEO57701.1 - 1.1e-42 145.7 0.4 2.1e-42 144.8 0.3 1.5 1 0 0 1 1 1 1 PXA domain Nucleoplasmin PF03066.10 AEO57702.1 - 2.9 7.3 8.9 6.2 6.3 6.2 1.6 1 0 0 1 1 1 0 Nucleoplasmin HTH_Tnp_Tc5 PF03221.11 AEO57703.1 - 1.2e-10 41.0 0.0 3.1e-10 39.7 0.0 1.7 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.8 AEO57703.1 - 2.7e-07 29.9 0.0 4.6e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain MAP65_ASE1 PF03999.7 AEO57703.1 - 0.0021 16.7 1.8 0.0038 15.9 1.2 1.4 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) MarR PF01047.17 AEO57703.1 - 0.0029 17.2 0.0 0.038 13.7 0.0 2.4 2 0 0 2 2 2 1 MarR family HTH_Tnp_4 PF13613.1 AEO57703.1 - 0.011 15.2 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease MarR_2 PF12802.2 AEO57703.1 - 0.029 14.0 0.1 0.23 11.1 0.0 2.2 2 0 0 2 2 2 0 MarR family HTH_38 PF13936.1 AEO57703.1 - 0.081 12.4 0.0 0.25 10.9 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4 PF04545.11 AEO57703.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 TGS PF02824.16 AEO57706.1 - 1.4e-22 79.2 0.2 2.7e-22 78.3 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 AEO57706.1 - 1.7e-17 63.4 0.0 4.7e-17 61.9 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 AEO57706.1 - 8.6e-09 34.8 0.0 2.4e-08 33.4 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 AEO57706.1 - 0.00015 21.6 0.1 0.021 14.6 0.0 2.4 1 1 1 2 2 2 1 Dynamin family GTP_EFTU PF00009.22 AEO57706.1 - 0.00039 19.8 0.1 1.2 8.5 0.0 3.8 2 2 1 3 3 3 2 Elongation factor Tu GTP binding domain DUF211 PF02680.9 AEO57706.1 - 0.022 14.5 0.1 0.1 12.4 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized ArCR, COG1888 ArgK PF03308.11 AEO57706.1 - 0.023 13.4 0.2 0.12 11.1 0.0 2.0 2 0 0 2 2 2 0 ArgK protein Steroid_dh PF02544.11 AEO57709.1 - 1.1e-09 38.2 6.8 2.1e-09 37.3 4.5 1.6 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ATP-synt_DE_N PF02823.11 AEO57710.1 - 1e-18 66.8 0.1 1.5e-18 66.2 0.1 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DUF2457 PF10446.4 AEO57711.1 - 1.5e-160 534.9 51.0 1.5e-160 534.9 35.3 3.3 2 2 0 2 2 2 1 Protein of unknown function (DUF2457) Nop14 PF04147.7 AEO57711.1 - 0.29 9.0 31.1 0.69 7.7 21.5 1.6 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 AEO57711.1 - 8.2 5.5 28.6 27 3.8 19.8 1.9 1 0 0 1 1 1 0 SDA1 Arf PF00025.16 AEO57712.1 - 1.5e-66 222.9 0.0 1.7e-66 222.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 AEO57712.1 - 1.5e-10 40.3 0.1 7e-07 28.2 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 AEO57712.1 - 1.1e-07 32.3 0.0 1.5e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 AEO57712.1 - 1.8e-07 30.6 0.0 2.4e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 AEO57712.1 - 2e-07 30.9 0.0 2.7e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 AEO57712.1 - 3.5e-07 29.6 0.0 4.6e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 AEO57712.1 - 1.6e-05 24.1 0.0 1.7e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 AEO57712.1 - 0.00078 18.9 0.0 0.033 13.6 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 AEO57712.1 - 0.12 11.8 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 AEO57712.1 - 0.14 11.6 0.0 10 5.5 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF3336 PF11815.3 AEO57713.1 - 8.3e-58 194.0 3.3 1.6e-57 193.1 2.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 AEO57713.1 - 1.6e-21 77.1 1.2 6.6e-21 75.1 0.0 2.5 2 0 0 2 2 2 1 Patatin-like phospholipase zf-C2H2 PF00096.21 AEO57715.1 - 5.3 7.5 11.6 7.7 7.0 1.5 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type Polysacc_deac_1 PF01522.16 AEO57716.1 - 1.9e-13 50.1 0.1 3.1e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.14 AEO57716.1 - 0.0038 17.1 19.8 0.0038 17.1 13.8 3.4 3 1 0 3 3 3 1 Chitin recognition protein HSP20 PF00011.16 AEO57718.1 - 0.11 12.3 1.2 0.36 10.7 0.8 1.8 1 0 0 1 1 1 0 Hsp20/alpha crystallin family DUF4604 PF15377.1 AEO57718.1 - 0.21 11.8 7.1 0.14 12.3 2.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) DUF2201_N PF13203.1 AEO57718.1 - 4.3 6.4 8.8 0.58 9.2 1.8 2.1 2 0 0 2 2 2 0 Putative metallopeptidase domain Aldedh PF00171.17 AEO57719.1 - 4.6e-185 615.3 0.1 5.2e-185 615.1 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 AEO57719.1 - 0.00048 19.4 0.0 0.013 14.7 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF1487) LMBR1 PF04791.11 AEO57720.1 - 1.8e-25 89.4 10.3 6.3e-25 87.6 7.2 1.7 1 1 0 1 1 1 1 LMBR1-like membrane protein HTH_Tnp_1 PF01527.15 AEO57720.1 - 0.091 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Transposase SGL PF08450.7 AEO57722.1 - 5.3e-68 229.0 0.0 6.2e-68 228.8 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Reg_prop PF07494.6 AEO57722.1 - 0.011 15.6 0.7 0.99 9.6 0.0 3.1 2 0 0 2 2 2 0 Two component regulator propeller bZIP_1 PF00170.16 AEO57723.1 - 2.9e-07 30.3 13.6 5.8e-07 29.3 9.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 AEO57723.1 - 7.8e-06 25.6 20.3 8.9e-06 25.4 13.1 1.9 1 1 0 1 1 1 1 Basic region leucine zipper GAS PF13851.1 AEO57723.1 - 0.043 13.0 5.5 0.068 12.3 3.8 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4140 PF13600.1 AEO57723.1 - 0.41 11.1 3.4 0.91 10.0 2.3 1.5 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) APG6 PF04111.7 AEO57723.1 - 0.44 9.5 6.2 0.67 8.9 4.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Bap31 PF05529.7 AEO57723.1 - 0.72 9.2 1.4 1.2 8.5 1.0 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DivIC PF04977.10 AEO57723.1 - 1.1 8.8 7.7 0.8 9.2 4.2 1.6 1 1 0 1 1 1 0 Septum formation initiator IncA PF04156.9 AEO57723.1 - 4.7 6.7 13.3 0.22 11.1 5.0 1.7 2 0 0 2 2 2 0 IncA protein Baculo_PEP_C PF04513.7 AEO57725.1 - 0.082 12.7 10.1 0.034 13.9 3.3 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF883 PF05957.8 AEO57725.1 - 0.47 10.8 2.4 6.5 7.2 1.3 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Tape_meas_lam_C PF09718.5 AEO57725.1 - 0.8 9.6 12.1 0.36 10.7 2.5 2.5 2 1 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DUF2217 PF10265.4 AEO57725.1 - 4.8 5.8 8.8 6.4 5.4 6.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) SIN1 PF05422.7 AEO57726.1 - 1.4e-36 126.1 0.7 1.8e-21 76.2 0.5 3.0 2 1 0 2 2 2 2 Stress-activated map kinase interacting protein 1 (SIN1) TUG-UBL1 PF11470.3 AEO57726.1 - 0.048 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 GLUT4 regulating protein TUG PRCC PF10253.4 AEO57727.1 - 4e-33 115.6 9.6 4e-33 115.6 6.7 2.7 3 0 0 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting KCl_Cotrans_1 PF03522.10 AEO57727.1 - 0.81 9.2 6.4 9.2 5.8 0.5 2.7 2 0 0 2 2 2 0 K-Cl Co-transporter type 1 (KCC1) Zds_C PF08632.5 AEO57728.1 - 0.079 12.3 0.2 0.18 11.2 0.2 1.6 1 0 0 1 1 1 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term UCH PF00443.24 AEO57729.1 - 1.6e-42 145.4 2.2 3.2e-42 144.5 1.5 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3517 PF12030.3 AEO57729.1 - 2e-24 85.7 0.0 5.1e-24 84.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3517) UCH_1 PF13423.1 AEO57729.1 - 2.6e-18 66.4 0.7 4.7e-18 65.6 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_P_pop3 PF08228.6 AEO57730.1 - 1.2e-11 44.7 0.0 2.2e-07 30.8 0.0 2.1 2 0 0 2 2 2 2 RNase P subunit Pop3 Aldolase_II PF00596.16 AEO57730.1 - 0.092 12.3 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Class II Aldolase and Adducin N-terminal domain Pyr_redox_2 PF07992.9 AEO57731.1 - 1.5e-35 122.9 0.0 4.5e-35 121.3 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AEO57731.1 - 1.8e-12 47.4 0.0 4.1e-10 39.9 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AEO57731.1 - 0.00081 19.5 0.0 0.096 12.7 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Anillin PF08174.6 AEO57732.1 - 4.2e-34 117.5 0.5 1.3e-33 115.9 0.3 1.9 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.24 AEO57732.1 - 1.4e-07 31.6 0.0 4.1e-07 30.1 0.0 1.9 1 0 0 1 1 1 1 PH domain His_biosynth PF00977.16 AEO57734.1 - 4.6e-33 114.4 0.0 5.8e-33 114.0 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein TMP-TENI PF02581.12 AEO57734.1 - 0.1 11.6 0.1 1.7 7.7 0.0 2.1 2 0 0 2 2 2 0 Thiamine monophosphate synthase/TENI Ribul_P_3_epim PF00834.14 AEO57734.1 - 0.12 11.4 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family DUF4602 PF15375.1 AEO57735.1 - 0.00045 20.3 7.5 0.00045 20.3 5.2 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF4602) STE PF02200.11 AEO57736.1 - 3.8e-62 207.2 0.2 7.2e-62 206.3 0.2 1.5 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.21 AEO57736.1 - 7.4e-12 44.8 10.4 1.5e-06 28.1 0.6 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AEO57736.1 - 5.5e-10 38.8 10.5 3.4e-05 23.8 0.4 3.0 3 0 0 3 3 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AEO57736.1 - 2e-08 34.1 3.1 2e-08 34.1 2.1 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 AEO57736.1 - 0.00055 19.7 0.1 0.00055 19.7 0.1 2.7 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 AEO57736.1 - 0.0033 17.5 1.3 0.048 13.8 0.2 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding FYDLN_acid PF09538.5 AEO57736.1 - 0.018 15.6 0.6 0.06 13.9 0.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zf-Di19 PF05605.7 AEO57736.1 - 0.048 13.8 2.5 0.096 12.8 1.8 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-TRAF PF02176.13 AEO57736.1 - 0.12 12.8 2.2 0.2 12.0 1.5 1.3 1 0 0 1 1 1 0 TRAF-type zinc finger zf-C2HC_2 PF13913.1 AEO57736.1 - 0.88 9.3 3.1 4.1 7.1 0.1 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type NOA36 PF06524.7 AEO57736.1 - 3.4 6.8 8.3 5.5 6.1 5.8 1.3 1 0 0 1 1 1 0 NOA36 protein NOC3p PF07540.6 AEO57738.1 - 7e-32 109.5 0.1 3.4e-31 107.3 0.0 2.3 1 0 0 1 1 1 1 Nucleolar complex-associated protein CBF PF03914.12 AEO57738.1 - 1.1e-31 109.4 0.1 7.5e-31 106.7 0.0 2.2 2 0 0 2 2 2 1 CBF/Mak21 family BP28CT PF08146.7 AEO57739.1 - 6.1e-43 146.1 1.5 1.1e-42 145.3 0.1 2.2 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 AEO57739.1 - 3.6e-24 85.0 0.8 3.6e-24 85.0 0.5 7.1 8 2 0 8 8 8 1 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.1 AEO57739.1 - 6.1e-07 29.6 20.8 0.013 15.7 0.3 7.4 7 0 0 7 7 7 3 HEAT repeats HEAT PF02985.17 AEO57739.1 - 0.017 15.1 0.2 0.017 15.1 0.1 6.0 7 0 0 7 7 7 0 HEAT repeat Pex26 PF07163.7 AEO57740.1 - 0.016 14.1 0.3 0.03 13.2 0.2 1.4 1 0 0 1 1 1 0 Pex26 protein SAPS PF04499.10 AEO57740.1 - 0.037 12.6 0.3 0.047 12.3 0.2 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein GAGA_bind PF06217.7 AEO57740.1 - 0.08 12.8 0.5 0.14 12.1 0.3 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family MIP-T3 PF10243.4 AEO57740.1 - 0.48 8.8 20.5 0.77 8.1 14.2 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 eIF3_subunit PF08597.5 AEO57740.1 - 0.56 9.7 18.3 0.84 9.1 12.7 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit CDC27 PF09507.5 AEO57740.1 - 1.2 8.3 17.0 1.7 7.7 11.8 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 U79_P34 PF03064.11 AEO57740.1 - 8.8 5.7 12.3 20 4.5 8.5 1.6 1 0 0 1 1 1 0 HSV U79 / HCMV P34 PHF5 PF03660.9 AEO57741.1 - 1.6e-51 172.8 10.6 1.8e-51 172.6 7.3 1.0 1 0 0 1 1 1 1 PHF5-like protein DZR PF12773.2 AEO57741.1 - 0.97 9.2 15.7 17 5.3 10.0 2.8 1 1 0 1 1 1 0 Double zinc ribbon Prok-RING_1 PF14446.1 AEO57741.1 - 1.4 8.7 15.7 2.9 7.6 0.5 3.1 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 PolC_DP2 PF03833.8 AEO57741.1 - 4.5 4.8 5.8 4.5 4.8 4.0 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 PHD PF00628.24 AEO57741.1 - 8.1 6.2 15.6 0.22 11.2 4.5 2.5 1 1 1 2 2 2 0 PHD-finger Pinin_SDK_memA PF04696.8 AEO57742.1 - 2.7e-22 78.7 17.7 2.7e-22 78.7 12.3 1.8 1 1 1 2 2 2 1 pinin/SDK/memA/ protein conserved region Abhydrolase_6 PF12697.2 AEO57743.1 - 1e-31 110.5 0.2 1.5e-31 110.0 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO57743.1 - 2.1e-14 53.6 0.0 3.7e-10 39.7 0.0 2.9 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AEO57743.1 - 2.5e-13 49.9 0.0 1.2e-12 47.7 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 AEO57743.1 - 6.6e-05 22.6 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_4 PF08386.5 AEO57743.1 - 0.0052 16.6 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_2 PF02230.11 AEO57743.1 - 0.059 12.8 0.0 0.16 11.3 0.0 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Chlorophyllase PF07224.6 AEO57743.1 - 0.12 11.1 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Peptidase_S28 PF05577.7 AEO57743.1 - 0.2 10.1 0.0 0.26 9.8 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Cript PF10235.4 AEO57744.1 - 4.4e-31 107.0 9.3 6.8e-31 106.4 6.4 1.3 1 0 0 1 1 1 1 Microtubule-associated protein CRIPT DZR PF12773.2 AEO57744.1 - 0.0019 17.9 20.0 0.0069 16.1 6.0 2.6 2 1 1 3 3 3 2 Double zinc ribbon zinc_ribbon_2 PF13240.1 AEO57744.1 - 0.016 14.6 2.9 0.016 14.6 2.0 3.0 3 0 0 3 3 3 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 AEO57744.1 - 0.17 11.1 11.2 0.084 12.1 1.0 3.1 3 0 0 3 3 3 0 zinc-ribbon domain DUF2039 PF10217.4 AEO57744.1 - 0.24 11.4 14.1 0.035 14.1 4.8 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) Ribosomal_L32p PF01783.18 AEO57744.1 - 0.33 11.1 12.4 0.16 12.1 2.0 3.0 2 1 1 3 3 3 0 Ribosomal L32p protein family Thioredoxin_7 PF13899.1 AEO57744.1 - 0.51 10.3 0.0 0.51 10.3 0.0 2.1 3 0 0 3 3 3 0 Thioredoxin-like zf-C3HC4_3 PF13920.1 AEO57744.1 - 3.6 7.3 14.7 30 4.3 7.5 2.9 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO57744.1 - 8.1 6.2 14.2 17 5.2 7.4 2.7 2 1 1 3 3 3 0 zinc-RING finger domain E1-E2_ATPase PF00122.15 AEO57745.1 - 5.2e-22 78.0 0.0 9.1e-22 77.2 0.0 1.3 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 AEO57745.1 - 1.5e-21 77.4 0.1 3.8e-21 76.1 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 AEO57745.1 - 2.4e-18 67.3 0.5 1.2e-17 65.0 0.4 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AEO57745.1 - 4.5e-13 48.9 0.0 1.2e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 AEO57745.1 - 0.00047 19.8 0.5 0.0035 16.9 0.4 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 AEO57745.1 - 0.03 14.5 0.0 0.095 12.9 0.0 1.8 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Ecl1 PF12855.2 AEO57746.1 - 9.1e-09 34.4 2.1 1.6e-08 33.6 1.4 1.3 1 0 0 1 1 1 1 Life-span regulatory factor DNA_pol_viral_N PF00242.12 AEO57746.1 - 0.069 12.1 1.7 0.11 11.5 1.2 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain stn_TNFRSF12A PF12191.3 AEO57748.1 - 0.019 15.0 0.0 0.031 14.3 0.0 1.3 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Herpes_gE PF02480.11 AEO57748.1 - 0.052 11.8 0.1 0.069 11.3 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Rax2 PF12768.2 AEO57748.1 - 0.066 12.4 0.0 0.23 10.6 0.0 1.8 3 0 0 3 3 3 0 Cortical protein marker for cell polarity Kelch_6 PF13964.1 AEO57748.1 - 0.34 11.1 5.8 0.52 10.5 0.2 2.6 2 1 0 2 2 2 0 Kelch motif Kelch_1 PF01344.20 AEO57748.1 - 0.37 10.3 2.3 17 5.0 0.1 2.5 2 0 0 2 2 2 0 Kelch motif MFS_1 PF07690.11 AEO57749.1 - 2.9e-16 59.1 49.8 8.1e-09 34.6 10.6 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily WAC_Acf1_DNA_bd PF10537.4 AEO57750.1 - 3.2e-39 133.1 0.0 1.4e-38 131.1 0.0 2.2 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 AEO57750.1 - 1.1e-16 60.3 0.6 1.8e-16 59.6 0.4 1.4 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 AEO57750.1 - 6.5e-13 48.0 0.9 1.5e-12 46.9 0.6 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM1 PF15612.1 AEO57750.1 - 0.0014 18.4 0.1 0.0057 16.5 0.0 2.1 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 WHIM3 PF15614.1 AEO57750.1 - 0.0015 18.2 0.0 0.0053 16.5 0.0 2.0 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 3 Alg6_Alg8 PF03155.10 AEO57751.1 - 9.6e-142 473.1 30.0 1.2e-141 472.8 20.8 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Lectin_leg-like PF03388.8 AEO57752.1 - 1.2e-28 99.8 0.0 3.5e-28 98.2 0.0 1.7 2 0 0 2 2 2 1 Legume-like lectin family Baculo_PEP_C PF04513.7 AEO57752.1 - 0.013 15.3 0.1 0.5 10.1 0.0 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ING PF12998.2 AEO57752.1 - 0.055 13.7 0.8 0.52 10.6 0.1 2.2 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding COMP PF11598.3 AEO57752.1 - 0.28 11.2 1.2 3.1 7.9 0.9 2.2 1 1 0 1 1 1 0 Cartilage oligomeric matrix protein Peptidase_M24 PF00557.19 AEO57753.1 - 4.1e-60 202.8 0.0 1.3e-59 201.2 0.0 1.8 1 1 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 AEO57753.1 - 3.6e-24 84.6 0.0 7.7e-24 83.5 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Fungal_trans PF04082.13 AEO57754.1 - 2.3e-21 75.8 0.0 3.4e-21 75.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain RPN7 PF10602.4 AEO57756.1 - 3.3e-49 166.6 0.1 5.6e-49 165.9 0.0 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 AEO57756.1 - 9.7e-16 57.9 0.0 2.4e-15 56.7 0.0 1.7 1 0 0 1 1 1 1 PCI domain DUF2200 PF09966.4 AEO57756.1 - 0.05 13.4 0.0 1.1 9.1 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2200) Prp18 PF02840.10 AEO57757.1 - 2.5e-51 173.2 0.8 3.5e-51 172.8 0.0 1.6 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.6 AEO57757.1 - 2.4e-12 45.8 0.2 2.4e-12 45.8 0.1 3.2 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like Serglycin PF04360.7 AEO57757.1 - 0.043 13.5 1.1 0.091 12.4 0.8 1.5 1 0 0 1 1 1 0 Serglycin Nop14 PF04147.7 AEO57757.1 - 1.3 6.8 21.3 1.7 6.4 14.8 1.1 1 0 0 1 1 1 0 Nop14-like family Ycf1 PF05758.7 AEO57757.1 - 3.5 5.2 5.1 4.7 4.7 3.5 1.1 1 0 0 1 1 1 0 Ycf1 CAF-1_p150 PF11600.3 AEO57757.1 - 3.7 6.8 27.5 6.3 6.1 19.1 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF45 PF01863.12 AEO57757.1 - 4.9 6.8 10.2 4.3 7.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF45 SAP18 PF06487.7 AEO57758.1 - 2.1e-33 114.7 0.0 2.6e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) GST_N PF02798.15 AEO57760.1 - 6.9e-08 32.5 0.0 1.3e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 AEO57760.1 - 2.2e-06 27.7 0.0 5.1e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 AEO57760.1 - 3.5e-05 23.6 0.0 6.3e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 AEO57760.1 - 9.4e-05 22.3 0.0 0.0002 21.2 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 AEO57760.1 - 0.00025 20.9 0.0 0.00073 19.4 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 AEO57760.1 - 0.0077 16.7 0.0 0.014 15.8 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Abhydrolase_6 PF12697.2 AEO57761.1 - 0.00011 22.1 0.3 0.00011 22.1 0.2 2.8 2 2 0 2 2 2 1 Alpha/beta hydrolase family LCAT PF02450.10 AEO57761.1 - 0.074 12.0 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF676 PF05057.9 AEO57761.1 - 0.08 12.2 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) HTH_29 PF13551.1 AEO57762.1 - 6.9e-05 22.9 0.0 8.9e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 AEO57762.1 - 0.0055 16.3 0.1 0.0072 15.9 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_r4_2 PF08281.7 AEO57762.1 - 0.082 12.3 0.3 0.11 11.9 0.2 1.2 1 0 0 1 1 1 0 Sigma-70, region 4 CcoS PF03597.10 AEO57763.1 - 5.9 6.4 6.5 1.5 8.3 0.5 2.7 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type MIF PF01187.13 AEO57764.1 - 7e-09 35.7 0.0 1.1e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Gtr1_RagA PF04670.7 AEO57765.1 - 1.8e-71 239.9 0.1 2.3e-71 239.6 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 AEO57765.1 - 0.00049 20.5 0.0 0.0024 18.3 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 AEO57765.1 - 0.012 14.8 0.0 0.022 14.0 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family AIG2 PF06094.7 AEO57766.1 - 4.3e-06 27.1 0.0 6.7e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family AIG2_2 PF13772.1 AEO57766.1 - 0.039 14.0 0.0 3.3 7.8 0.0 2.4 2 0 0 2 2 2 0 AIG2-like family NERD PF08378.6 AEO57767.1 - 0.059 13.6 0.1 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Nuclease-related domain C_GCAxxG_C_C PF09719.5 AEO57767.1 - 0.18 11.5 0.1 0.27 11.0 0.1 1.2 1 0 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) DUF2428 PF10350.4 AEO57768.1 - 3.3e-68 229.4 0.0 7.6e-68 228.2 0.0 1.7 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 AEO57768.1 - 8.9e-08 31.5 13.9 4.1 7.7 0.0 8.2 7 0 0 7 7 7 4 HEAT repeat HEAT_2 PF13646.1 AEO57768.1 - 1.6e-06 28.3 6.8 0.0047 17.1 0.0 5.9 5 1 0 5 5 5 1 HEAT repeats HEAT_EZ PF13513.1 AEO57768.1 - 5.6 7.5 15.1 1.3 9.5 0.5 5.9 6 1 1 7 7 7 0 HEAT-like repeat Tim17 PF02466.14 AEO57769.1 - 2.8e-27 95.2 3.2 3.8e-27 94.8 2.2 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family LRR_4 PF12799.2 AEO57769.1 - 0.13 11.9 0.3 0.25 10.9 0.2 1.5 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) RVT_1 PF00078.22 AEO57771.1 - 0.00041 19.7 0.2 0.00043 19.7 0.2 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3786 PF12654.2 AEO57771.1 - 0.085 12.1 0.1 0.094 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3786) FlgN PF05130.7 AEO57772.1 - 0.0051 17.0 1.4 0.0081 16.4 1.0 1.4 1 0 0 1 1 1 1 FlgN protein APG6 PF04111.7 AEO57772.1 - 0.0056 15.7 0.5 0.0069 15.4 0.3 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 OmpH PF03938.9 AEO57772.1 - 0.036 13.9 0.4 0.047 13.6 0.3 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1599 PF07659.6 AEO57772.1 - 0.086 12.9 2.6 5.7 7.0 0.1 2.3 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1599) DUF1664 PF07889.7 AEO57772.1 - 0.15 11.8 0.3 0.23 11.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Fzo_mitofusin PF04799.8 AEO57772.1 - 0.2 11.0 1.1 0.29 10.5 0.8 1.2 1 0 0 1 1 1 0 fzo-like conserved region DUF724 PF05266.9 AEO57772.1 - 0.22 11.1 3.0 0.61 9.6 2.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF724) CALCOCO1 PF07888.6 AEO57772.1 - 1.5 7.0 9.3 1.9 6.7 6.5 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2852 PF11014.3 AEO57772.1 - 2.5 8.0 6.2 2.6 8.0 3.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) CoaE PF01121.15 AEO57774.1 - 5.6e-42 143.1 0.0 2.3e-41 141.1 0.0 1.8 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 AEO57774.1 - 0.00031 21.5 0.8 0.0019 18.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 AEO57774.1 - 0.00034 20.5 0.3 0.0043 16.9 0.2 2.5 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.1 AEO57774.1 - 0.024 14.9 1.2 0.26 11.6 0.0 2.5 3 0 0 3 3 3 0 AAA domain CcmH PF03918.9 AEO57774.1 - 0.041 12.8 0.7 0.076 12.0 0.5 1.4 1 0 0 1 1 1 0 Cytochrome C biogenesis protein SKI PF01202.17 AEO57774.1 - 0.071 12.9 0.0 10 5.9 0.0 2.5 2 1 0 2 2 2 0 Shikimate kinase FixP_N PF14715.1 AEO57774.1 - 0.66 9.4 3.4 1.1 8.7 2.3 1.3 1 0 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP eIF-5_eIF-2B PF01873.12 AEO57776.1 - 1.6e-40 137.5 0.0 4.2e-40 136.2 0.0 1.7 2 0 0 2 2 2 1 Domain found in IF2B/IF5 W2 PF02020.13 AEO57776.1 - 9.7e-27 92.7 0.9 3e-26 91.1 0.6 1.9 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon RNA_pol_Rpb1_5 PF04998.12 AEO57776.1 - 0.19 10.9 2.8 0.49 9.6 1.9 1.6 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Zn-ribbon_8 PF09723.5 AEO57776.1 - 0.22 11.4 1.0 0.56 10.2 0.7 1.6 1 0 0 1 1 1 0 Zinc ribbon domain p450 PF00067.17 AEO57777.1 - 3.4e-43 147.8 0.0 4e-43 147.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1749 PF08538.5 AEO57779.1 - 5.3e-88 294.8 0.0 6.4e-88 294.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 AEO57779.1 - 1.7e-12 47.7 0.6 2.5e-12 47.1 0.4 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO57779.1 - 3.4e-07 30.1 0.4 8.3e-07 28.8 0.2 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family BRF1 PF07741.8 AEO57780.1 - 2.9 8.1 7.8 22 5.3 0.0 3.7 3 1 0 3 3 3 0 Brf1-like TBP-binding domain HEAT PF02985.17 AEO57781.1 - 0.00029 20.6 7.1 0.014 15.3 0.7 5.3 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.1 AEO57781.1 - 0.0024 18.1 5.7 1 9.7 0.0 5.1 4 0 0 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 AEO57781.1 - 0.82 10.2 10.9 0.81 10.2 1.1 5.2 5 0 0 5 5 5 0 HEAT-like repeat NAD_binding_10 PF13460.1 AEO57782.1 - 4.3e-15 56.1 0.0 2e-13 50.7 0.0 2.3 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 AEO57782.1 - 2.7e-06 26.9 0.0 1.3e-05 24.8 0.0 2.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 AEO57782.1 - 8.4e-05 21.4 0.0 0.00041 19.1 0.0 2.0 2 1 1 3 3 3 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 AEO57782.1 - 0.00058 18.8 0.1 0.019 13.9 0.0 2.4 2 1 0 2 2 2 1 Male sterility protein adh_short PF00106.20 AEO57782.1 - 0.023 14.6 0.0 0.12 12.3 0.0 2.2 3 0 0 3 3 3 0 short chain dehydrogenase RmlD_sub_bind PF04321.12 AEO57782.1 - 0.024 13.5 0.0 0.25 10.2 0.0 2.5 2 1 0 2 2 2 0 RmlD substrate binding domain NmrA PF05368.8 AEO57782.1 - 0.076 12.2 0.1 0.46 9.6 0.0 2.0 2 0 0 2 2 2 0 NmrA-like family YEATS PF03366.11 AEO57783.1 - 5e-30 103.0 0.4 8.5e-30 102.3 0.3 1.4 1 0 0 1 1 1 1 YEATS family IncA PF04156.9 AEO57783.1 - 0.022 14.3 0.2 0.03 13.9 0.1 1.1 1 0 0 1 1 1 0 IncA protein DUF4191 PF13829.1 AEO57783.1 - 0.034 13.2 1.6 0.047 12.8 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) TPD52 PF04201.10 AEO57783.1 - 0.054 13.2 4.1 0.085 12.5 2.8 1.3 1 0 0 1 1 1 0 Tumour protein D52 family TMF_DNA_bd PF12329.3 AEO57783.1 - 0.49 10.2 12.2 2.8 7.8 6.6 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF2404 PF10296.4 AEO57784.1 - 0.00054 20.0 0.0 0.0018 18.3 0.0 1.8 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) Ins_P5_2-kin PF06090.7 AEO57785.1 - 3e-28 98.7 0.0 1.2e-16 60.6 0.0 2.0 1 1 1 2 2 2 2 Inositol-pentakisphosphate 2-kinase Nucleoside_tran PF01733.13 AEO57786.1 - 9.2e-35 120.2 5.6 9.2e-35 120.2 3.9 3.2 2 1 0 2 2 2 1 Nucleoside transporter MFS_1 PF07690.11 AEO57786.1 - 3.4e-08 32.6 37.2 4.9e-05 22.2 6.6 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily BC10 PF06726.7 AEO57786.1 - 0.092 12.7 4.7 0.081 12.9 1.4 2.3 2 0 0 2 2 2 0 Bladder cancer-related protein BC10 Catalase PF00199.14 AEO57787.1 - 3.9e-163 542.6 0.1 4.9e-163 542.2 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 AEO57787.1 - 2.2e-19 69.0 0.0 4e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 AEO57787.1 - 0.044 13.2 0.2 0.085 12.3 0.1 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family DUF3635 PF12330.3 AEO57788.1 - 1.2e-05 25.3 0.0 0.00035 20.5 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3635) DUF1682 PF07946.9 AEO57789.1 - 1.8e-102 342.4 0.2 2.1e-102 342.2 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) 5TM-5TMR_LYT PF07694.7 AEO57789.1 - 0.14 11.5 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 5TMR of 5TMR-LYT DUF2058 PF09831.4 AEO57789.1 - 0.82 9.5 15.6 1.3 8.8 10.8 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) DUF77 PF01910.12 AEO57790.1 - 2e-33 113.9 1.7 2.3e-33 113.7 1.2 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF77 Polysacc_deac_1 PF01522.16 AEO57790.1 - 0.0019 17.8 0.1 0.0026 17.3 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Acid_PPase PF12689.2 AEO57790.1 - 0.084 12.4 0.1 0.13 11.8 0.1 1.3 1 1 0 1 1 1 0 Acid Phosphatase DUF2834 PF11196.3 AEO57791.1 - 0.035 14.2 2.5 0.69 10.0 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2834) MFS_1 PF07690.11 AEO57794.1 - 2.2e-32 112.1 24.1 2.2e-32 112.1 16.7 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4231 PF14015.1 AEO57794.1 - 0.013 15.4 1.8 0.045 13.7 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) DUF1129 PF06570.6 AEO57794.1 - 2.8 7.2 8.0 0.16 11.2 0.1 2.7 2 2 1 3 3 3 0 Protein of unknown function (DUF1129) TPP_enzyme_N PF02776.13 AEO57796.1 - 7.4e-39 132.9 1.2 3e-38 130.9 0.1 2.3 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 AEO57796.1 - 6e-25 87.5 0.1 1.1e-24 86.7 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 AEO57796.1 - 5.6e-20 71.4 0.0 3e-19 69.1 0.0 2.2 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain Arf PF00025.16 AEO57797.1 - 7e-39 132.8 0.0 1.1e-38 132.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 AEO57797.1 - 5.8e-15 54.8 0.0 4.2e-10 38.8 0.0 2.0 2 0 0 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 AEO57797.1 - 1e-08 34.6 0.0 1.2e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 AEO57797.1 - 7.2e-07 28.5 0.0 1.7e-06 27.4 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 AEO57797.1 - 1.3e-06 27.9 0.0 3.1e-06 26.6 0.0 1.6 1 1 0 1 1 1 1 Ras family GTP_EFTU PF00009.22 AEO57797.1 - 0.00011 21.7 0.0 0.00035 20.0 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 AEO57797.1 - 0.0002 21.8 0.0 0.00067 20.1 0.0 1.9 1 1 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 AEO57797.1 - 0.01 15.7 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase RNase_PH PF01138.16 AEO57798.1 - 1.4e-22 80.4 0.0 2.3e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 AEO57798.1 - 1.5e-07 31.2 0.0 2.7e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Cwf_Cwc_15 PF04889.7 AEO57799.1 - 9.2e-85 284.2 12.3 1.5e-84 283.5 8.6 1.3 1 1 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF2890 PF11081.3 AEO57799.1 - 0.24 11.4 10.4 0.46 10.5 7.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) CDC45 PF02724.9 AEO57799.1 - 0.77 7.7 16.6 1 7.3 11.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Di19_C PF14571.1 AEO57799.1 - 1.8 8.9 8.8 15 5.9 0.0 2.7 3 0 0 3 3 3 0 Stress-induced protein Di19, C-terminal DUF4637 PF15470.1 AEO57799.1 - 9.3 5.8 13.4 17 4.9 8.8 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4637) EBP PF05241.7 AEO57800.1 - 7.7e-61 204.5 4.3 9.1e-61 204.2 3.0 1.0 1 0 0 1 1 1 1 Emopamil binding protein Abhydrolase_9_N PF15420.1 AEO57800.1 - 0.034 13.8 0.6 0.38 10.4 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus Nol1_Nop2_Fmu PF01189.12 AEO57801.1 - 8.4e-23 81.1 0.0 9e-16 58.0 0.0 2.5 2 0 0 2 2 2 2 NOL1/NOP2/sun family DUF1996 PF09362.5 AEO57802.1 - 5.2e-61 206.3 0.0 9.5e-61 205.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) TPR_11 PF13414.1 AEO57803.1 - 1.3e-25 88.8 18.5 9.3e-07 28.4 0.0 7.9 8 0 0 8 8 8 5 TPR repeat TPR_1 PF00515.23 AEO57803.1 - 5.7e-16 57.3 6.7 0.018 14.6 0.0 8.1 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.12 AEO57803.1 - 4.1e-12 45.0 21.1 0.38 10.7 0.0 10.6 12 0 0 12 12 11 4 Tetratricopeptide repeat TPR_8 PF13181.1 AEO57803.1 - 6.8e-12 44.2 1.9 0.26 11.1 0.0 8.2 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_12 PF13424.1 AEO57803.1 - 9.3e-12 44.7 22.4 0.0074 16.1 0.0 8.0 7 2 1 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.1 AEO57803.1 - 1.8e-10 41.1 30.2 0.0016 19.0 0.0 9.5 10 1 1 11 11 11 2 Tetratricopeptide repeat TPR_19 PF14559.1 AEO57803.1 - 4e-10 39.8 10.9 0.19 12.0 0.0 7.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 AEO57803.1 - 1.2e-09 37.9 22.7 0.065 13.8 0.0 11.2 10 3 3 13 13 12 1 Tetratricopeptide repeat TPR_17 PF13431.1 AEO57803.1 - 2.1e-07 30.5 0.4 51 4.4 0.0 8.1 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_7 PF13176.1 AEO57803.1 - 5.6e-07 28.8 12.8 0.032 14.0 0.0 7.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_20 PF14561.1 AEO57803.1 - 6.4e-06 26.2 1.9 0.068 13.2 0.0 4.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 AEO57803.1 - 0.005 17.2 13.1 0.5 10.9 0.1 7.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_4 PF07721.9 AEO57803.1 - 0.018 15.3 5.4 46 4.8 0.0 6.2 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_21 PF09976.4 AEO57803.1 - 0.11 12.3 6.3 3.5 7.5 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat SAM_2 PF07647.12 AEO57804.1 - 4.9e-11 42.3 0.2 9.2e-11 41.4 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 AEO57804.1 - 8.1e-06 25.9 0.3 1.7e-05 24.8 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.5 AEO57804.1 - 0.024 14.5 0.4 0.068 13.0 0.2 1.7 1 0 0 1 1 1 0 IGR protein motif Ribosomal_L29e PF01779.12 AEO57805.1 - 1.6e-23 82.2 9.3 2.5e-23 81.6 6.4 1.3 1 0 0 1 1 1 1 Ribosomal L29e protein family DUF2423 PF10338.4 AEO57805.1 - 1.4 8.9 4.9 8.2 6.4 2.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2423) Mito_carr PF00153.22 AEO57806.1 - 8.5e-59 195.2 3.1 1.1e-21 76.2 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_C2 PF00648.16 AEO57807.1 - 1.8e-29 102.6 0.0 2.7e-29 102.1 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 AEO57807.1 - 2.9e-16 59.4 0.0 1.7e-14 53.7 0.0 2.8 2 1 0 2 2 2 1 Calpain large subunit, domain III zf-C2H2 PF00096.21 AEO57808.1 - 4.2e-09 36.2 8.9 0.0017 18.5 1.2 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AEO57808.1 - 9.4e-09 34.9 10.0 0.00018 21.6 1.6 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AEO57808.1 - 3.8e-06 26.9 8.0 0.28 11.5 0.2 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-Di19 PF05605.7 AEO57808.1 - 0.1 12.7 0.8 0.1 12.7 0.5 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding ADH_N PF08240.7 AEO57811.1 - 9.5e-24 83.2 1.1 1.9e-23 82.2 0.8 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AEO57811.1 - 6.2e-14 51.6 0.1 9.6e-14 51.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Sen15 PF09631.5 AEO57812.1 - 6.7e-25 87.2 0.0 1.3e-24 86.3 0.0 1.5 1 1 0 1 1 1 1 Sen15 protein TRAM_LAG1_CLN8 PF03798.11 AEO57813.1 - 2.4e-32 112.0 22.7 2.4e-32 112.0 15.7 1.8 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 AEO57813.1 - 1.6e-24 85.2 0.7 3.9e-24 83.9 0.0 2.1 2 0 0 2 2 2 1 TRAM1-like protein Med3 PF11593.3 AEO57813.1 - 7.7 5.6 6.6 14 4.8 3.1 1.9 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal ABC_tran PF00005.22 AEO57814.1 - 3.6e-30 105.0 0.0 7.6e-30 103.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 AEO57814.1 - 2.5e-25 89.4 3.9 5e-25 88.4 2.7 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region SbcCD_C PF13558.1 AEO57814.1 - 0.0049 16.7 0.1 0.05 13.5 0.1 2.6 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 AEO57814.1 - 0.018 15.0 0.0 0.98 9.3 0.0 2.2 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 AEO57814.1 - 0.019 14.1 0.0 0.037 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 AEO57814.1 - 0.023 14.1 0.1 0.067 12.7 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain EnY2 PF10163.4 AEO57815.1 - 0.087 12.7 0.0 0.27 11.1 0.0 1.7 2 0 0 2 2 2 0 Transcription factor e(y)2 AAA PF00004.24 AEO57816.1 - 1.7e-98 325.9 0.0 9.1e-48 161.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 AEO57816.1 - 1.7e-19 69.5 0.6 5.5e-19 67.9 0.4 2.0 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 AEO57816.1 - 5.8e-14 51.7 0.0 3.5e-06 26.2 0.0 2.8 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 AEO57816.1 - 7.4e-14 52.0 0.0 1.8e-07 31.2 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 AEO57816.1 - 5.1e-13 48.9 0.5 9.4e-07 28.6 0.1 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 AEO57816.1 - 1.3e-12 47.7 0.0 1.6e-05 24.7 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 AEO57816.1 - 3.5e-12 46.6 0.3 0.00068 19.7 0.1 4.2 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 AEO57816.1 - 8.6e-12 45.4 0.0 0.00029 20.8 0.0 3.7 2 2 1 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 AEO57816.1 - 2.3e-11 44.5 0.1 0.00033 21.4 0.0 3.4 2 1 0 2 2 2 2 AAA domain TIP49 PF06068.8 AEO57816.1 - 2.6e-09 36.2 0.1 0.00084 18.1 0.0 2.7 2 0 0 2 2 2 2 TIP49 C-terminus AAA_25 PF13481.1 AEO57816.1 - 4e-09 36.1 5.6 0.017 14.4 0.0 4.8 3 2 2 5 5 4 3 AAA domain AAA_14 PF13173.1 AEO57816.1 - 2.5e-08 33.8 0.0 0.0014 18.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 AEO57816.1 - 2.7e-08 33.4 0.0 0.0053 16.1 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 AEO57816.1 - 4.2e-08 32.8 2.1 0.0083 15.8 0.0 3.1 3 0 0 3 3 2 2 Part of AAA domain DUF815 PF05673.8 AEO57816.1 - 1.1e-07 30.9 0.0 0.00064 18.7 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 AEO57816.1 - 1.6e-07 30.6 0.2 0.0057 15.8 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 AEO57816.1 - 1.9e-07 30.3 0.1 0.011 14.8 0.0 2.7 3 0 0 3 3 2 2 Zeta toxin CDC48_2 PF02933.12 AEO57816.1 - 3.4e-07 29.7 0.0 9.8e-07 28.3 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 RNA_helicase PF00910.17 AEO57816.1 - 4.7e-07 29.9 0.0 0.026 14.6 0.0 2.9 3 0 0 3 3 2 2 RNA helicase KaiC PF06745.8 AEO57816.1 - 5.8e-07 28.8 0.8 0.22 10.5 0.0 3.5 2 1 1 3 3 3 2 KaiC AAA_18 PF13238.1 AEO57816.1 - 1.2e-06 28.8 0.0 0.086 13.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 AEO57816.1 - 1.5e-06 28.1 0.0 0.0021 17.8 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_24 PF13479.1 AEO57816.1 - 2.4e-06 27.3 0.3 0.096 12.2 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_28 PF13521.1 AEO57816.1 - 2.6e-06 27.4 0.1 0.09 12.7 0.0 2.9 3 0 0 3 3 2 2 AAA domain Parvo_NS1 PF01057.12 AEO57816.1 - 7.8e-06 24.9 0.1 0.043 12.6 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 AEO57816.1 - 1e-05 25.6 0.0 0.045 13.8 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Arch_ATPase PF01637.13 AEO57816.1 - 1.3e-05 25.0 0.0 4.1 7.0 0.0 4.0 2 2 1 3 3 3 0 Archaeal ATPase Sigma54_activat PF00158.21 AEO57816.1 - 1.5e-05 24.5 0.1 0.16 11.4 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain NACHT PF05729.7 AEO57816.1 - 1.6e-05 24.6 0.0 0.086 12.5 0.0 3.3 3 0 0 3 3 3 1 NACHT domain ABC_tran PF00005.22 AEO57816.1 - 1.7e-05 25.1 0.0 0.24 11.7 0.0 3.6 2 1 0 2 2 2 2 ABC transporter Bac_DnaA PF00308.13 AEO57816.1 - 2.6e-05 23.9 0.0 0.17 11.4 0.0 3.1 3 0 0 3 3 3 2 Bacterial dnaA protein PhoH PF02562.11 AEO57816.1 - 0.00013 21.2 0.2 0.5 9.5 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein Vps4_C PF09336.5 AEO57816.1 - 0.00017 21.4 0.1 0.00082 19.2 0.0 2.1 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain AAA_3 PF07726.6 AEO57816.1 - 0.00018 21.1 0.0 0.58 9.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 AEO57816.1 - 0.00018 21.1 0.0 0.5 9.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.1 AEO57816.1 - 0.00033 20.2 0.0 0.6 9.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 AEO57816.1 - 0.00045 19.1 0.1 0.55 9.0 0.0 2.8 3 0 0 3 3 3 2 NB-ARC domain NTPase_1 PF03266.10 AEO57816.1 - 0.00067 19.4 0.3 0.65 9.6 0.0 3.9 3 0 0 3 3 3 1 NTPase DUF2075 PF09848.4 AEO57816.1 - 0.0016 17.5 0.0 1.5 7.7 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) KAP_NTPase PF07693.9 AEO57816.1 - 0.0056 15.7 0.3 1.1 8.2 0.0 3.5 2 2 1 4 4 4 1 KAP family P-loop domain Viral_helicase1 PF01443.13 AEO57816.1 - 0.0065 16.0 0.0 0.28 10.6 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase IPT PF01745.11 AEO57816.1 - 0.011 14.9 0.0 1.5 7.9 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase UPF0079 PF02367.12 AEO57816.1 - 0.018 14.6 0.1 8.9 5.9 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 AEO57816.1 - 0.026 13.9 0.5 1.6 8.1 0.0 3.4 3 1 0 4 4 4 0 AAA-like domain Zot PF05707.7 AEO57816.1 - 0.033 13.6 0.1 12 5.2 0.1 3.9 3 1 0 3 3 3 0 Zonular occludens toxin (Zot) T2SE PF00437.15 AEO57816.1 - 0.034 13.0 0.0 1.4 7.7 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_23 PF13476.1 AEO57816.1 - 0.062 13.6 0.3 4.3 7.5 0.0 2.9 3 0 0 3 3 2 0 AAA domain AFG1_ATPase PF03969.11 AEO57816.1 - 0.087 11.6 0.0 10 4.7 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase SKI PF01202.17 AEO57816.1 - 0.09 12.6 0.1 8.3 6.2 0.0 2.7 2 0 0 2 2 2 0 Shikimate kinase KTI12 PF08433.5 AEO57816.1 - 0.12 11.5 0.4 11 5.0 0.0 2.8 3 0 0 3 3 2 0 Chromatin associated protein KTI12 MobB PF03205.9 AEO57816.1 - 0.13 11.9 0.7 3.5 7.3 0.0 3.1 4 0 0 4 4 2 0 Molybdopterin guanine dinucleotide synthesis protein B AhpC-TSA_2 PF13911.1 AEO57817.1 - 5.5e-07 29.5 0.1 1.1e-06 28.5 0.1 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Fungal_trans_2 PF11951.3 AEO57817.1 - 6.4e-06 25.0 0.0 1.1e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fork_head PF00250.13 AEO57818.1 - 1.1e-33 115.0 0.1 2e-33 114.2 0.1 1.3 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 AEO57818.1 - 0.00014 21.9 0.0 0.00025 21.1 0.0 1.5 1 0 0 1 1 1 1 FHA domain CLU PF13236.1 AEO57819.1 - 4.1e-82 274.9 0.0 6.9e-82 274.1 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 AEO57819.1 - 5.4e-52 176.1 0.0 5.4e-52 176.1 0.0 2.1 2 0 0 2 2 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.1 AEO57819.1 - 3.2e-31 107.1 16.8 2.2e-11 43.5 0.1 3.7 1 1 3 4 4 4 4 Tetratricopeptide repeat CLU_N PF15044.1 AEO57819.1 - 2.1e-23 82.2 0.1 4.9e-23 81.0 0.0 1.7 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.1 AEO57819.1 - 7.8e-18 63.7 4.0 0.00027 20.7 0.0 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat DUF727 PF05303.7 AEO57819.1 - 0.00051 19.7 0.0 0.0012 18.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_8 PF13181.1 AEO57819.1 - 0.027 14.2 2.9 0.44 10.4 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat CDC45 PF02724.9 AEO57819.1 - 0.073 11.1 4.3 0.11 10.4 3.0 1.3 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.10 AEO57819.1 - 0.096 11.3 4.3 0.16 10.5 3.0 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DDHD PF02862.12 AEO57819.1 - 0.11 12.2 6.3 0.03 14.1 2.1 1.7 2 0 0 2 2 2 0 DDHD domain TPR_2 PF07719.12 AEO57819.1 - 0.17 11.9 11.6 1.1 9.3 0.3 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat NPR3 PF03666.8 AEO57819.1 - 2.1 6.7 8.0 3.8 5.9 5.6 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 GAGA_bind PF06217.7 AEO57819.1 - 2.8 7.8 7.3 1 9.2 1.6 2.6 3 0 0 3 3 3 0 GAGA binding protein-like family TRAP_alpha PF03896.11 AEO57819.1 - 5.7 5.8 9.1 11 4.9 6.3 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Vfa1 PF08432.5 AEO57819.1 - 8.8 6.3 26.9 0.18 11.8 13.6 1.8 2 0 0 2 2 1 0 AAA-ATPase Vps4-associated protein 1 TSA PF03249.8 AEO57820.1 - 0.42 9.1 3.4 0.68 8.4 2.3 1.2 1 0 0 1 1 1 0 Type specific antigen SDA1 PF05285.7 AEO57820.1 - 0.54 9.4 8.0 1.1 8.4 5.5 1.5 1 0 0 1 1 1 0 SDA1 NAD_binding_6 PF08030.7 AEO57821.1 - 4.8e-20 72.0 0.0 3.5e-17 62.7 0.0 2.5 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 AEO57821.1 - 2.7e-19 69.4 10.4 2.7e-19 69.4 7.2 2.1 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 AEO57821.1 - 2.1e-13 50.0 0.0 9e-13 48.0 0.0 2.0 1 1 0 1 1 1 1 FAD-binding domain Yippee-Mis18 PF03226.9 AEO57822.1 - 6.1e-24 83.8 0.4 7e-24 83.6 0.3 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HNH_5 PF14279.1 AEO57822.1 - 0.0036 17.2 0.3 0.12 12.4 0.0 2.2 2 0 0 2 2 2 1 HNH endonuclease DUF2039 PF10217.4 AEO57822.1 - 0.027 14.4 0.9 0.098 12.6 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) Endonuclease_7 PF02945.10 AEO57822.1 - 0.035 13.8 1.9 0.063 12.9 1.3 1.6 1 1 0 1 1 1 0 Recombination endonuclease VII RIG-I_C-RD PF11648.3 AEO57822.1 - 0.13 12.0 0.8 0.26 11.1 0.5 1.5 1 1 0 1 1 1 0 C-terminal domain of RIG-I Nuc_sug_transp PF04142.10 AEO57823.1 - 1.8e-08 33.7 0.5 3.8e-08 32.7 0.1 1.7 2 0 0 2 2 2 1 Nucleotide-sugar transporter EamA PF00892.15 AEO57823.1 - 2.4e-06 27.5 22.5 3.7e-05 23.7 1.5 3.3 3 1 0 3 3 3 2 EamA-like transporter family UAA PF08449.6 AEO57823.1 - 1.4e-05 24.1 6.2 2.4e-05 23.4 4.3 1.3 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 AEO57823.1 - 0.0047 16.5 14.2 0.11 12.1 0.3 2.8 3 0 0 3 3 3 2 Triose-phosphate Transporter family HXXEE PF13787.1 AEO57823.1 - 4.5 7.6 9.3 89 3.4 1.8 4.2 4 0 0 4 4 4 0 Protein of unknown function with HXXEE motif DUF2985 PF11204.3 AEO57824.1 - 1.1e-35 121.2 1.8 1.1e-35 121.2 1.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) DIM1 PF02966.11 AEO57825.1 - 6.5e-70 232.8 0.0 7.3e-70 232.6 0.0 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_8 PF13905.1 AEO57825.1 - 0.055 13.5 0.2 0.089 12.9 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin-like DNA_pol_A_exo1 PF01612.15 AEO57826.1 - 9.4e-13 48.0 0.0 2.1e-10 40.3 0.0 2.1 2 0 0 2 2 2 2 3'-5' exonuclease PalH PF08733.5 AEO57827.1 - 1.5e-107 359.4 0.0 1.8e-107 359.1 0.0 1.1 1 0 0 1 1 1 1 PalH/RIM21 SH3_1 PF00018.23 AEO57829.1 - 0.014 14.7 0.0 0.031 13.6 0.0 1.6 1 0 0 1 1 1 0 SH3 domain Serinc PF03348.10 AEO57829.1 - 0.47 9.0 3.1 0.79 8.3 2.2 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) MAPEG PF01124.13 AEO57830.1 - 4.7e-13 48.8 2.9 5.5e-13 48.6 2.0 1.1 1 0 0 1 1 1 1 MAPEG family BTP PF05232.7 AEO57830.1 - 0.18 11.5 0.1 0.18 11.5 0.0 2.1 1 1 1 2 2 2 0 Bacterial Transmembrane Pair family MFS_2 PF13347.1 AEO57831.1 - 2.7e-11 42.5 4.9 2.7e-11 42.5 3.4 3.0 4 0 0 4 4 4 1 MFS/sugar transport protein DUF1228 PF06779.9 AEO57831.1 - 0.21 11.6 6.0 1.6 8.8 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) HAMP PF00672.20 AEO57831.1 - 2 8.6 0.0 2 8.6 0.0 3.9 5 0 0 5 5 5 0 HAMP domain Na_H_Exchanger PF00999.16 AEO57832.1 - 2e-67 227.4 38.8 2.4e-67 227.1 26.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Pyr_redox_2 PF07992.9 AEO57834.1 - 1.2e-26 93.8 0.0 3.4e-17 62.9 0.0 3.2 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AEO57834.1 - 4.2e-14 52.7 0.1 6.8e-13 48.8 0.2 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AEO57834.1 - 0.00096 19.2 0.3 1.6 8.7 0.1 3.0 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Fibrinogen_aC PF12160.3 AEO57834.1 - 0.69 9.4 3.0 1.6 8.2 2.1 1.6 1 0 0 1 1 1 0 Fibrinogen alpha C domain Tubulin_3 PF14881.1 AEO57835.1 - 1.4e-63 213.6 0.0 6.2e-54 182.2 0.0 2.2 2 0 0 2 2 2 2 Tubulin domain Misat_Tub_SegII PF10644.4 AEO57835.1 - 1.4e-38 131.4 0.0 2.8e-38 130.4 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 AEO57835.1 - 0.0002 21.2 0.0 0.49 10.1 0.0 2.3 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain PAP_central PF04928.12 AEO57836.1 - 2.4e-101 337.8 0.0 3.3e-101 337.3 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 AEO57836.1 - 5.3e-46 155.9 0.0 1.4e-45 154.6 0.0 1.7 1 1 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 AEO57836.1 - 4.7e-07 30.0 0.0 1.4e-06 28.5 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain Abhydrolase_5 PF12695.2 AEO57837.1 - 8.2e-07 28.8 0.8 2e-06 27.6 0.5 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 AEO57837.1 - 3.9e-06 26.6 0.0 7.4e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 AEO57837.1 - 0.0001 22.3 0.9 0.00019 21.3 0.6 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 AEO57837.1 - 0.0012 18.2 0.0 0.0018 17.5 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_3 PF07859.8 AEO57837.1 - 0.0028 17.2 0.1 0.012 15.1 0.0 2.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold Thioesterase PF00975.15 AEO57837.1 - 0.011 16.0 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Lipase_3 PF01764.20 AEO57837.1 - 0.012 15.2 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_2 PF02230.11 AEO57837.1 - 0.085 12.2 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF915 PF06028.6 AEO57837.1 - 0.15 11.1 0.0 4.9 6.1 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) PTPLA PF04387.9 AEO57838.1 - 1e-31 109.5 9.9 1.4e-31 109.1 6.8 1.2 1 1 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA tRNA-synt_2d PF01409.15 AEO57840.1 - 1.6e-10 40.6 0.0 1.6e-10 40.5 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2d PF01409.15 AEO57841.1 - 3.6e-69 232.6 0.0 5.5e-69 232.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 AEO57841.1 - 1.8e-05 23.6 0.1 0.00031 19.6 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 AEO57841.1 - 0.00013 21.6 0.0 0.00076 19.1 0.0 2.1 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Arf PF00025.16 AEO57842.1 - 3.1e-73 244.7 0.1 3.6e-73 244.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 AEO57842.1 - 2.6e-12 46.3 0.0 3.2e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 AEO57842.1 - 3.9e-11 42.2 0.5 2.6e-07 29.6 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 AEO57842.1 - 1.3e-10 40.8 0.0 1.6e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AEO57842.1 - 1.5e-08 35.1 0.0 2.1e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 AEO57842.1 - 1.7e-08 33.9 0.0 2e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 AEO57842.1 - 2.4e-06 27.5 0.0 3.3e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 AEO57842.1 - 4.7e-05 22.8 0.1 0.0064 15.9 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain ArgK PF03308.11 AEO57842.1 - 0.001 17.8 0.5 0.0032 16.2 0.1 2.0 2 1 0 2 2 2 1 ArgK protein FeoB_N PF02421.13 AEO57842.1 - 0.025 13.8 0.7 0.12 11.5 0.5 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B VWA_CoxE PF05762.9 AEO57842.1 - 0.13 11.3 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein Ribosomal_L39 PF00832.15 AEO57843.1 - 1.2e-22 79.0 8.8 1.3e-22 78.9 6.1 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Skp1 PF01466.14 AEO57844.1 - 4.6e-40 135.5 2.1 8.3e-40 134.6 1.5 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 AEO57844.1 - 2.7e-19 68.9 0.1 7.4e-19 67.6 0.0 1.8 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain DUF4375 PF14300.1 AEO57844.1 - 0.049 13.6 1.6 0.065 13.2 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) Glyco_transf_22 PF03901.12 AEO57845.1 - 5.3e-60 203.5 15.7 6.3e-60 203.3 10.9 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF2346 PF09803.4 AEO57846.1 - 0.00055 19.7 3.4 0.0012 18.7 2.2 1.8 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2346) Transcrip_reg PF01709.15 AEO57847.1 - 3.4e-62 209.6 0.1 4e-62 209.4 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator dCMP_cyt_deam_2 PF08211.6 AEO57847.1 - 0.051 13.5 0.1 0.097 12.6 0.0 1.5 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region LPP20 PF02169.11 AEO57847.1 - 0.091 12.8 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 LPP20 lipoprotein HEAT_2 PF13646.1 AEO57848.1 - 1.9e-12 47.3 19.5 0.00036 20.7 0.0 8.4 6 2 1 8 8 8 4 HEAT repeats HEAT PF02985.17 AEO57848.1 - 6.7e-07 28.8 22.1 0.018 15.1 0.1 10.5 13 0 0 13 13 13 3 HEAT repeat Vac14_Fab1_bd PF12755.2 AEO57848.1 - 0.00014 22.1 0.0 0.021 15.1 0.0 4.1 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region DUF1640 PF07798.6 AEO57849.1 - 2.2e-12 47.4 2.5 2.2e-12 47.4 1.7 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1640) DUF1191 PF06697.7 AEO57849.1 - 7.3e-05 21.7 0.6 0.00011 21.1 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) RasGAP_C PF03836.10 AEO57849.1 - 0.44 10.2 4.7 1.7 8.2 0.3 2.4 2 1 0 2 2 2 0 RasGAP C-terminus Abhydrolase_6 PF12697.2 AEO57850.1 - 5.4e-26 91.8 3.4 9.4e-26 91.0 2.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO57850.1 - 6.6e-17 61.6 0.2 2.6e-16 59.6 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DSPc PF00782.15 AEO57850.1 - 5.4e-10 38.9 0.0 8.8e-10 38.2 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Abhydrolase_1 PF00561.15 AEO57850.1 - 2.5e-09 37.0 0.1 7.1e-08 32.2 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 AEO57850.1 - 6.9e-05 23.1 0.0 0.00011 22.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Ser_hydrolase PF06821.8 AEO57850.1 - 0.0022 17.6 0.1 0.62 9.6 0.0 2.4 2 0 0 2 2 2 1 Serine hydrolase PGAP1 PF07819.8 AEO57850.1 - 0.0031 17.1 0.2 0.023 14.2 0.1 2.0 1 1 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 AEO57850.1 - 0.0047 16.5 0.3 0.011 15.3 0.1 1.6 1 1 0 1 1 1 1 Lipase (class 3) DUF2305 PF10230.4 AEO57850.1 - 0.0049 16.3 0.0 0.0085 15.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) LCAT PF02450.10 AEO57850.1 - 0.016 14.1 0.0 0.026 13.5 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_3 PF07859.8 AEO57850.1 - 0.02 14.4 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.15 AEO57850.1 - 0.024 14.0 0.0 0.053 12.9 0.0 1.5 1 0 0 1 1 1 0 Putative esterase PTPlike_phytase PF14566.1 AEO57850.1 - 0.047 13.7 0.0 0.08 12.9 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Hydrolase_4 PF12146.3 AEO57850.1 - 0.051 13.4 0.0 0.21 11.4 0.0 2.0 2 0 0 2 2 2 0 Putative lysophospholipase Y_phosphatase PF00102.22 AEO57850.1 - 0.054 12.8 0.0 0.084 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase FSH1 PF03959.8 AEO57850.1 - 0.076 12.4 0.0 2.7 7.3 0.0 2.3 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Peptidase_S9 PF00326.16 AEO57850.1 - 0.084 12.0 0.0 3.2 6.9 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF900 PF05990.7 AEO57850.1 - 0.14 11.4 0.0 0.38 10.0 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Alk_phosphatase PF00245.15 AEO57852.1 - 2.6e-104 349.2 0.0 3.5e-104 348.8 0.0 1.2 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 AEO57852.1 - 0.00046 19.6 0.2 0.00097 18.5 0.1 1.5 1 0 0 1 1 1 1 Metalloenzyme superfamily SSP160 PF06933.6 AEO57852.1 - 0.0022 16.0 8.6 0.0036 15.3 5.9 1.3 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 Mucin PF01456.12 AEO57852.1 - 2.8 7.7 22.9 0.36 10.5 12.6 1.9 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF3439 PF11921.3 AEO57852.1 - 3.6 7.3 15.8 7.6 6.3 11.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) PDH PF02153.12 AEO57853.1 - 3.3e-16 58.9 0.0 4.6e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.10 AEO57853.1 - 4.8e-07 29.7 0.3 2.1e-06 27.7 0.0 2.1 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 AEO57853.1 - 3e-06 27.5 0.2 1.4e-05 25.4 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 AEO57853.1 - 0.00036 19.7 0.0 0.00073 18.7 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 AEO57853.1 - 0.013 15.1 0.0 0.057 13.0 0.0 1.9 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 AEO57853.1 - 0.02 14.3 0.0 0.037 13.4 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 AEO57853.1 - 0.021 14.9 0.0 0.042 13.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 AEO57853.1 - 0.044 13.7 0.0 0.089 12.7 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Rossmann-like PF10727.4 AEO57853.1 - 0.092 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Rossmann-like domain RCC1 PF00415.13 AEO57854.1 - 5.6e-32 109.7 23.3 2.1e-10 40.6 0.1 7.3 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 AEO57854.1 - 2.3e-18 65.3 28.4 8.8e-08 31.5 0.2 6.5 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat Rad9 PF04139.8 AEO57855.1 - 1.3e-76 257.0 0.1 1.5e-76 256.8 0.1 1.1 1 0 0 1 1 1 1 Rad9 APH PF01636.18 AEO57857.1 - 0.00018 21.3 0.0 0.00018 21.3 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 AEO57857.1 - 0.029 13.3 0.0 0.029 13.3 0.0 1.0 1 0 0 1 1 1 0 Fructosamine kinase Aminotran_5 PF00266.14 AEO57858.1 - 1.1e-12 47.3 0.0 2.2e-11 43.1 0.0 2.2 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 AEO57858.1 - 0.034 13.1 0.0 0.063 12.3 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family ELFV_dehydrog PF00208.16 AEO57859.1 - 9.4e-62 208.7 0.0 1.6e-61 207.9 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 AEO57859.1 - 1.9e-22 78.6 0.1 7.3e-17 60.1 0.0 2.4 3 0 0 3 3 3 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 AEO57859.1 - 4.4e-05 23.0 0.0 0.0002 20.9 0.0 2.1 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ADH_zinc_N PF00107.21 AEO57860.1 - 8.9e-16 57.6 0.0 1.4e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 AEO57860.1 - 1.2e-14 55.2 0.1 5.2e-14 53.2 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AEO57860.1 - 6.1e-05 22.7 0.0 0.00039 20.1 0.0 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ribosomal_L32e PF01655.13 AEO57861.1 - 3.8e-51 171.7 1.7 5.2e-51 171.3 1.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L32 DnaJ PF00226.26 AEO57862.1 - 8.5e-25 86.2 2.8 2.1e-24 85.0 1.9 1.7 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 AEO57862.1 - 5.7e-20 71.0 0.0 8.4e-18 64.0 0.0 2.6 2 0 0 2 2 2 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 AEO57862.1 - 4.7e-13 48.9 15.7 7.2e-13 48.3 10.9 1.3 1 0 0 1 1 1 1 DnaJ central domain UreE_N PF02814.10 AEO57862.1 - 0.0005 19.5 0.1 0.0011 18.4 0.1 1.6 1 0 0 1 1 1 1 UreE urease accessory protein, N-terminal domain HypA PF01155.14 AEO57862.1 - 0.016 14.8 6.5 0.21 11.2 0.5 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Val_tRNA-synt_C PF10458.4 AEO57862.1 - 0.11 12.6 1.1 0.25 11.4 0.7 1.6 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm APP_E2 PF12925.2 AEO57862.1 - 0.16 11.5 1.5 0.25 10.8 1.1 1.2 1 0 0 1 1 1 0 E2 domain of amyloid precursor protein zf-CHY PF05495.7 AEO57862.1 - 0.7 10.0 7.1 1.1 9.4 0.3 2.3 2 0 0 2 2 2 0 CHY zinc finger DUF1356 PF07092.7 AEO57862.1 - 1.6 7.8 4.0 6.7 5.8 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1356) RRN7 PF11781.3 AEO57862.1 - 4.1 6.9 8.6 2.1 7.9 0.0 3.0 3 1 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 tRNA-synt_1c PF00749.16 AEO57863.1 - 9e-66 221.6 0.0 1.3e-65 221.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain JAB PF01398.16 AEO57864.1 - 1.6e-26 92.2 0.0 2.6e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 AEO57864.1 - 2.9e-07 29.9 0.0 5e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Fmp27 PF10344.4 AEO57865.1 - 2.7e-249 829.4 0.0 4.6e-249 828.6 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Apt1 PF10351.4 AEO57865.1 - 6.9e-172 572.4 0.0 6.9e-172 572.4 0.0 2.5 3 0 0 3 3 3 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 AEO57865.1 - 5.6e-154 513.0 0.0 1.1e-153 512.0 0.0 1.5 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.4 AEO57865.1 - 1.4e-55 187.4 0.0 3e-55 186.4 0.0 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 AEO57865.1 - 1.8e-54 183.7 0.1 4.5e-54 182.4 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 AEO57865.1 - 5.6e-35 119.8 0.1 2.2e-34 117.9 0.1 2.2 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF3431 PF11913.3 AEO57866.1 - 2.9e-78 262.3 0.0 3.6e-78 262.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) RRM_6 PF14259.1 AEO57868.1 - 5.6e-14 51.8 0.0 1e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AEO57868.1 - 5.3e-10 38.7 0.1 1.2e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO57868.1 - 1.8e-05 24.5 0.0 3.6e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1510 PF07423.6 AEO57868.1 - 8.7 5.6 15.0 14 4.9 10.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) GTP_EFTU PF00009.22 AEO57869.1 - 4.4e-33 114.2 0.0 7.8e-33 113.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 AEO57869.1 - 1.5e-16 60.0 0.0 4e-16 58.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 AEO57869.1 - 6e-09 35.8 0.0 1.7e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 AEO57869.1 - 3e-08 33.3 0.0 6.5e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 AEO57869.1 - 4.6e-07 29.4 0.1 0.00095 18.7 0.0 3.3 4 0 0 4 4 4 2 Elongation factor G, domain IV DUF3379 PF11859.3 AEO57869.1 - 0.071 12.2 1.8 0.13 11.4 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3379) Paf67 PF10255.4 AEO57870.1 - 2.1e-145 484.6 0.1 2.7e-145 484.3 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 AEO57870.1 - 0.012 15.4 0.2 0.11 12.4 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat HBS1_N PF08938.5 AEO57870.1 - 0.15 12.2 1.4 0.29 11.2 1.0 1.5 1 0 0 1 1 1 0 HBS1 N-terminus Usp PF00582.21 AEO57872.1 - 9.2e-14 51.8 0.3 8.5e-13 48.6 0.0 2.3 2 0 0 2 2 2 1 Universal stress protein family YjeF_N PF03853.10 AEO57874.1 - 1.1e-42 145.5 0.0 1.5e-42 145.0 0.0 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 AEO57874.1 - 2.2e-13 50.6 1.1 6.4e-13 49.1 0.1 2.2 2 0 0 2 2 2 1 FDF domain Lactamase_B_2 PF12706.2 AEO57875.1 - 2e-10 40.5 0.0 3.2e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 AEO57875.1 - 2.3e-08 33.9 0.2 4.8e-08 32.8 0.1 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Amidohydro_2 PF04909.9 AEO57875.1 - 0.0011 18.5 0.1 0.0024 17.4 0.0 1.6 2 0 0 2 2 2 1 Amidohydrolase tRNA-synt_1g PF09334.6 AEO57876.1 - 2.7e-137 457.6 0.0 1.9e-136 454.8 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 AEO57876.1 - 1.5e-06 26.5 4.7 0.0027 15.7 0.0 4.2 4 1 1 5 5 5 3 tRNA synthetases class I (I, L, M and V) DUF1682 PF07946.9 AEO57876.1 - 0.033 13.0 6.9 0.052 12.3 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) CRCB PF02537.10 AEO57877.1 - 5.7e-27 93.9 28.1 1.4e-17 63.6 7.6 3.5 3 1 0 3 3 3 2 CrcB-like protein UPRTase PF14681.1 AEO57878.1 - 3.9e-74 248.3 0.0 4.4e-74 248.1 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 AEO57878.1 - 1.6e-06 27.8 0.0 2.9e-06 27.0 0.0 1.6 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyl_synth PF14572.1 AEO57878.1 - 0.16 11.6 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl synthetase-associated domain DNA_ligase_A_M PF01068.16 AEO57879.1 - 4.1e-44 150.3 0.0 8.9e-44 149.2 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 AEO57879.1 - 6.6e-37 127.0 0.0 1.2e-36 126.1 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 AEO57879.1 - 3.7e-17 62.5 0.7 4.6e-16 58.9 0.0 2.7 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 AEO57879.1 - 9e-08 32.1 0.0 1.2e-06 28.5 0.0 2.5 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain DNA_ligase_IV PF11411.3 AEO57879.1 - 5e-05 22.9 0.0 9.9e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 DNA ligase IV mRNA_cap_enzyme PF01331.14 AEO57879.1 - 0.066 12.8 0.0 0.7 9.5 0.0 2.4 1 1 0 1 1 1 0 mRNA capping enzyme, catalytic domain PTCB-BRCT PF12738.2 AEO57879.1 - 0.1 12.4 0.0 12 5.8 0.0 2.6 2 0 0 2 2 2 0 twin BRCT domain LCD1 PF09798.4 AEO57879.1 - 0.57 8.1 0.2 0.86 7.5 0.2 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF4449 PF14613.1 AEO57880.1 - 8.4e-68 227.4 0.3 8.4e-68 227.4 0.2 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) Lipin_N PF04571.9 AEO57880.1 - 0.11 12.2 0.0 0.28 10.8 0.0 1.6 1 0 0 1 1 1 0 lipin, N-terminal conserved region DOT1 PF08123.8 AEO57881.1 - 3.8e-74 248.4 0.0 5.1e-74 248.0 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.1 AEO57881.1 - 5.4e-05 22.8 0.0 8.9e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO57881.1 - 9.5e-05 22.4 0.0 0.00017 21.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO57881.1 - 0.00021 21.8 0.0 0.00047 20.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ATG16 PF08614.6 AEO57882.1 - 1.7e-47 161.7 8.2 1.9e-47 161.6 5.7 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) AIP3 PF03915.8 AEO57882.1 - 4.8e-05 22.4 5.3 0.022 13.6 1.4 2.0 1 1 1 2 2 2 2 Actin interacting protein 3 CCDC144C PF14915.1 AEO57882.1 - 0.0016 17.4 13.4 0.1 11.4 7.0 2.1 2 0 0 2 2 2 2 CCDC144C protein coiled-coil region TPR_19 PF14559.1 AEO57882.1 - 0.0043 17.3 1.3 0.012 15.9 0.9 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat DUF4201 PF13870.1 AEO57882.1 - 0.0064 15.9 11.2 0.011 15.2 7.5 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4201) FlgN PF05130.7 AEO57882.1 - 0.23 11.7 17.8 0.33 11.1 11.1 1.9 2 0 0 2 2 2 0 FlgN protein ApbA_C PF08546.6 AEO57882.1 - 0.29 11.1 2.6 2.2 8.2 0.1 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal GAS PF13851.1 AEO57882.1 - 0.53 9.4 12.3 1.2 8.3 8.5 1.6 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.4 AEO57882.1 - 0.57 9.0 10.9 0.94 8.3 7.5 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 UPF0242 PF06785.6 AEO57882.1 - 2.1 6.9 8.5 2.9 6.4 5.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) DUF4061 PF13270.1 AEO57882.1 - 3.5 7.8 9.9 1.5 8.9 2.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4061) Vps16_N PF04841.8 AEO57883.1 - 4.8e-96 321.7 0.0 6.5e-96 321.3 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.7 AEO57883.1 - 8.1e-74 248.4 0.0 1.1e-73 247.9 0.0 1.1 1 0 0 1 1 1 1 Vps16, C-terminal region FHA PF00498.21 AEO57884.1 - 2.9e-16 59.3 0.0 5.1e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 AEO57884.1 - 2.7e-06 27.0 12.3 4.3e-06 26.4 8.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 AEO57884.1 - 9.9e-05 22.3 5.2 0.00017 21.6 3.6 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 AEO57884.1 - 0.032 13.8 12.9 0.051 13.2 9.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 AEO57884.1 - 0.057 13.2 2.6 0.099 12.4 1.8 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.24 AEO57884.1 - 0.095 12.4 7.2 0.18 11.5 5.0 1.5 1 0 0 1 1 1 0 PHD-finger lci PF12197.3 AEO57884.1 - 0.17 11.4 0.8 0.38 10.3 0.5 1.6 1 0 0 1 1 1 0 Bacillus cereus group antimicrobial protein zf-RING_5 PF14634.1 AEO57884.1 - 0.25 11.0 9.9 0.41 10.4 6.9 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING-like PF08746.6 AEO57884.1 - 0.43 10.6 8.1 0.74 9.8 5.6 1.4 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_2 PF13923.1 AEO57884.1 - 1.5 8.9 14.4 2.5 8.1 10.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Peptidase_M16_C PF05193.16 AEO57885.1 - 2.3e-55 187.1 0.0 6.3e-55 185.6 0.0 1.8 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 AEO57885.1 - 7.1e-43 145.9 0.0 1.3e-42 145.0 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) S1 PF00575.18 AEO57887.1 - 1.1e-95 313.7 35.6 2.4e-18 66.0 0.3 13.4 13 1 0 13 13 13 12 S1 RNA binding domain TPR_16 PF13432.1 AEO57887.1 - 1.8e-08 34.7 1.0 0.0013 19.3 0.0 4.0 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 AEO57887.1 - 3e-08 33.5 4.0 0.14 12.8 0.0 5.4 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 AEO57887.1 - 4.5e-07 30.1 0.6 0.028 14.7 0.0 3.9 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 AEO57887.1 - 7e-06 25.6 1.2 0.00024 20.7 0.1 3.0 3 0 0 3 3 3 1 TPR repeat S1_2 PF13509.1 AEO57887.1 - 1.3e-05 25.0 0.8 4 7.4 0.0 5.5 5 0 0 5 5 5 1 S1 domain TPR_17 PF13431.1 AEO57887.1 - 0.00043 20.2 0.4 39 4.7 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 AEO57887.1 - 0.0017 18.1 2.0 0.22 11.5 0.0 4.4 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 AEO57887.1 - 0.008 15.8 0.3 0.2 11.5 0.0 3.2 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 AEO57887.1 - 0.029 14.3 4.0 0.12 12.3 0.2 3.3 2 1 0 3 3 3 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 AEO57887.1 - 0.041 13.6 0.9 0.085 12.6 0.6 1.6 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 Ras_bdg_2 PF14847.1 AEO57887.1 - 0.097 12.6 2.3 4.7 7.1 0.1 3.7 2 1 1 3 3 3 0 Ras-binding domain of Byr2 Suf PF05843.9 AEO57887.1 - 0.18 11.4 10.6 0.77 9.4 0.3 4.1 2 1 1 3 3 3 0 Suppressor of forked protein (Suf) TPR_6 PF13174.1 AEO57887.1 - 1.1 9.8 2.7 16 6.1 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat ATPase_gene1 PF09527.5 AEO57890.1 - 1.7 8.5 6.8 13 5.6 0.8 3.3 3 0 0 3 3 3 0 Putative F0F1-ATPase subunit (ATPase_gene1) MAP65_ASE1 PF03999.7 AEO57891.1 - 6.5e-66 223.2 22.5 6.5e-66 223.2 15.6 2.4 2 1 0 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) Spectrin PF00435.16 AEO57891.1 - 0.33 11.2 15.0 0.38 11.0 0.8 4.2 4 0 0 4 4 4 0 Spectrin repeat EF-hand_4 PF12763.2 AEO57892.1 - 0.00015 21.4 0.0 0.00029 20.5 0.0 1.3 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand p450 PF00067.17 AEO57893.1 - 1.3e-13 50.2 0.0 1.5e-13 50.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HSP70 PF00012.15 AEO57894.1 - 1.1e-13 50.0 0.0 1.9e-13 49.2 0.0 1.4 1 1 0 1 1 1 1 Hsp70 protein Peptidase_M22 PF00814.20 AEO57894.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Glycoprotease family ABA_GPCR PF12430.3 AEO57897.1 - 9.3e-53 178.2 0.0 1.6e-52 177.5 0.0 1.4 1 0 0 1 1 1 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 AEO57897.1 - 1.8e-19 69.5 0.0 7.3e-19 67.5 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3735) DUF2729 PF10870.3 AEO57899.1 - 0.13 12.0 0.4 0.32 10.7 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2729) XAP5 PF04921.9 AEO57899.1 - 2.6 7.5 11.9 5.2 6.5 8.3 1.4 1 0 0 1 1 1 0 XAP5, circadian clock regulator zf-CCHC PF00098.18 AEO57900.1 - 0.0023 17.7 1.1 0.0033 17.2 0.8 1.2 1 0 0 1 1 1 1 Zinc knuckle Peptidase_S30 PF01577.11 AEO57900.1 - 0.023 14.1 1.7 0.027 13.8 1.2 1.1 1 0 0 1 1 1 0 Potyvirus P1 protease zf-CCHC PF00098.18 AEO57901.1 - 2.6e-07 30.2 1.7 4.1e-07 29.6 1.2 1.3 1 0 0 1 1 1 1 Zinc knuckle DUF1351 PF07083.6 AEO57902.1 - 0.017 14.7 0.0 0.018 14.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1351) Nha1_C PF08619.5 AEO57904.1 - 6.9e-93 312.2 43.5 4.5e-88 296.4 19.7 2.0 1 1 1 2 2 2 2 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.16 AEO57904.1 - 7.1e-69 232.1 20.2 8.5e-69 231.8 14.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 AEO57904.1 - 1.3 9.0 3.4 0.83 9.6 0.3 2.1 2 0 0 2 2 2 0 YrhC-like protein Tom22 PF04281.8 AEO57906.1 - 3.8e-43 146.2 0.2 5.1e-43 145.9 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Sigma70_ner PF04546.8 AEO57906.1 - 0.06 12.9 0.4 0.085 12.4 0.3 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region MDMPI_N PF11716.3 AEO57906.1 - 1.3 9.4 10.9 0.81 10.1 4.6 2.1 1 1 1 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain PP2C PF00481.16 AEO57907.1 - 2.1e-61 207.5 0.1 5.5e-51 173.4 0.1 3.1 1 1 2 3 3 3 3 Protein phosphatase 2C Snf7 PF03357.16 AEO57908.1 - 6.2e-36 123.3 15.2 1.2e-35 122.3 10.6 1.4 2 0 0 2 2 2 1 Snf7 V_ATPase_I PF01496.14 AEO57908.1 - 0.017 12.9 1.6 0.02 12.7 1.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4309 PF14172.1 AEO57908.1 - 0.042 13.8 0.0 0.085 12.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4309) DFF40 PF09230.5 AEO57908.1 - 0.3 10.4 3.3 0.39 10.0 2.3 1.2 1 0 0 1 1 1 0 DNA fragmentation factor 40 kDa YlqD PF11068.3 AEO57908.1 - 3.1 7.8 16.2 2.9 7.9 4.4 2.2 1 1 1 2 2 2 0 YlqD protein PspA_IM30 PF04012.7 AEO57908.1 - 3.9 6.7 15.5 1.5 8.0 2.5 2.2 1 1 1 2 2 2 0 PspA/IM30 family Dynamin_N PF00350.18 AEO57909.1 - 4.3e-17 62.4 1.2 8.9e-17 61.4 0.0 2.1 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 AEO57909.1 - 2.9e-09 36.8 0.0 1.2e-08 34.9 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 AEO57909.1 - 3.1e-07 29.9 0.5 5.2e-06 26.0 0.4 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IIGP PF05049.8 AEO57909.1 - 0.0022 16.8 0.0 0.0042 15.9 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Peripla_BP_4 PF13407.1 AEO57909.1 - 0.019 14.3 0.1 0.56 9.5 0.0 2.3 2 0 0 2 2 2 0 Periplasmic binding protein domain PduV-EutP PF10662.4 AEO57909.1 - 0.05 13.0 0.1 11 5.5 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.1 AEO57909.1 - 0.056 13.7 0.1 0.18 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 AEO57909.1 - 0.061 12.8 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain GvpK PF05121.7 AEO57909.1 - 0.17 11.7 2.8 4.6 7.1 0.0 3.3 3 0 0 3 3 3 0 Gas vesicle protein K A_deaminase PF00962.17 AEO57910.1 - 1.4e-27 96.5 0.0 1.8e-27 96.1 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase WD40 PF00400.27 AEO57911.1 - 1.3e-46 154.8 21.7 9.1e-10 38.0 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 AEO57911.1 - 7.3e-05 22.5 0.0 0.078 12.6 0.0 2.8 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cluap1 PF10234.4 AEO57911.1 - 0.076 12.2 0.7 0.11 11.7 0.5 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 Cep57_CLD_2 PF14197.1 AEO57911.1 - 0.26 11.2 2.7 0.21 11.5 0.7 1.6 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Phosducin PF02114.11 AEO57912.1 - 8.4e-09 34.5 0.1 0.00059 18.6 0.0 3.4 3 1 0 3 3 3 3 Phosducin Ran_BP1 PF00638.13 AEO57914.1 - 1.5e-47 160.6 1.5 3e-47 159.6 1.0 1.5 1 0 0 1 1 1 1 RanBP1 domain DUF1681 PF07933.9 AEO57914.1 - 0.0015 18.1 2.1 0.0025 17.3 1.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) PS-DH PF14765.1 AEO57914.1 - 0.025 13.7 0.2 0.025 13.7 0.2 1.6 2 0 0 2 2 2 0 Polyketide synthase dehydratase YEATS PF03366.11 AEO57915.1 - 1.3e-23 82.4 0.1 2.9e-23 81.3 0.1 1.6 1 0 0 1 1 1 1 YEATS family Baculo_8kDa PF06096.6 AEO57915.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.5 1 1 0 1 1 1 0 Baculoviridae 8.2 KDa protein AMP-binding PF00501.23 AEO57917.1 - 2.2e-46 158.1 0.0 2.6e-46 157.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 AEO57917.1 - 1.2e-06 29.3 0.5 4.5e-06 27.5 0.0 2.3 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain Aminotran_1_2 PF00155.16 AEO57918.1 - 8.2e-58 196.0 0.0 1.2e-57 195.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 AEO57918.1 - 0.011 14.8 0.0 0.021 13.9 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_5 PF00266.14 AEO57918.1 - 0.022 13.4 0.0 0.034 12.8 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Anti-adapt_IraP PF10796.4 AEO57918.1 - 0.19 12.1 0.0 0.37 11.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-S stabilisation anti-adaptor protein DUF4211 PF13926.1 AEO57919.1 - 7.3e-40 135.8 0.9 9.1e-39 132.3 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4211) Fe_hyd_SSU PF02256.12 AEO57919.1 - 0.034 14.1 0.3 1 9.4 0.0 3.0 3 0 0 3 3 3 0 Iron hydrogenase small subunit PBP_sp32 PF07222.7 AEO57919.1 - 0.062 12.4 17.9 0.24 10.5 8.4 2.4 2 0 0 2 2 2 0 Proacrosin binding protein sp32 U1snRNP70_N PF12220.3 AEO57919.1 - 7.7 6.9 12.7 2.7 8.3 2.7 3.1 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal SAM_2 PF07647.12 AEO57920.1 - 3e-17 62.2 0.0 6e-17 61.2 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 AEO57920.1 - 8e-16 57.9 0.0 1.5e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 AEO57920.1 - 4.8e-14 52.6 0.0 1.1e-13 51.4 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Joubert PF15392.1 AEO57920.1 - 0.048 12.8 0.8 0.078 12.2 0.5 1.3 1 0 0 1 1 1 0 Joubert syndrome-associated Hamartin PF04388.7 AEO57921.1 - 0.05 12.2 5.0 0.078 11.6 3.4 1.2 1 0 0 1 1 1 0 Hamartin protein SBDS_C PF09377.5 AEO57922.1 - 1.6e-54 182.8 0.1 2.4e-54 182.3 0.1 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 AEO57922.1 - 3.1e-30 103.8 0.1 5.5e-30 103.0 0.1 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein FlxA PF14282.1 AEO57922.1 - 0.0058 16.5 23.4 0.012 15.5 16.2 1.5 1 0 0 1 1 1 1 FlxA-like protein DUF3512 PF12024.3 AEO57922.1 - 0.023 13.9 2.4 0.052 12.8 1.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3512) HCV_NS5a_C PF12941.2 AEO57922.1 - 0.026 14.1 3.0 0.044 13.3 2.1 1.3 1 0 0 1 1 1 0 HCV NS5a protein C-terminal region Hid1 PF12722.2 AEO57922.1 - 0.032 11.9 3.3 0.035 11.7 2.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Band_3_cyto PF07565.8 AEO57922.1 - 0.069 12.6 2.4 0.096 12.1 1.6 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Ctr PF04145.10 AEO57922.1 - 0.097 12.7 1.1 0.16 12.0 0.7 1.3 1 0 0 1 1 1 0 Ctr copper transporter family FLO_LFY PF01698.11 AEO57922.1 - 0.097 11.4 4.0 0.14 10.9 2.8 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein FimP PF09766.4 AEO57922.1 - 0.1 11.6 8.6 0.15 11.1 6.0 1.1 1 0 0 1 1 1 0 Fms-interacting protein Ndc1_Nup PF09531.5 AEO57922.1 - 0.11 10.8 4.5 0.15 10.4 3.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pex26 PF07163.7 AEO57922.1 - 0.18 10.7 3.3 0.26 10.1 2.3 1.2 1 0 0 1 1 1 0 Pex26 protein Vps39_1 PF10366.4 AEO57922.1 - 0.21 11.6 4.0 0.55 10.2 2.8 1.7 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 APC_CDC26 PF10471.4 AEO57922.1 - 0.23 12.2 15.9 0.54 11.0 11.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 TFIIA PF03153.8 AEO57922.1 - 0.34 10.7 15.1 0.43 10.4 10.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3533 PF12051.3 AEO57922.1 - 0.65 8.6 2.4 0.91 8.1 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Pex16 PF08610.5 AEO57922.1 - 0.76 8.7 6.0 1 8.2 4.2 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) DUF4557 PF15101.1 AEO57922.1 - 1 9.1 8.8 1.6 8.4 6.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Shisa PF13908.1 AEO57922.1 - 7.3 6.7 12.6 4.4 7.4 7.4 1.6 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Peptidase_S10 PF00450.17 AEO57923.1 - 8.6e-132 440.2 1.2 1.1e-131 439.8 0.8 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.6 AEO57923.1 - 3.7e-05 23.8 0.0 7.2e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Abhydrolase_6 PF12697.2 AEO57923.1 - 6.7e-05 22.8 0.0 0.00087 19.2 0.0 2.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family PDEase_I PF00233.14 AEO57924.1 - 6.2e-42 143.9 2.1 2.6e-39 135.3 0.1 2.2 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase DUF4005 PF13178.1 AEO57925.1 - 0.31 11.2 5.1 0.34 11.1 3.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4005) UCH PF00443.24 AEO57926.1 - 6e-74 248.5 0.0 5.2e-73 245.4 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AEO57926.1 - 6.7e-15 55.2 0.0 2.5e-06 27.1 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 AEO57926.1 - 1.8e-12 47.5 0.0 4.6e-12 46.1 0.0 1.8 1 0 0 1 1 1 1 DUSP domain Peptidase_M16_C PF05193.16 AEO57927.1 - 2e-41 141.6 0.1 8.6e-21 74.4 0.0 3.5 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 AEO57927.1 - 9.6e-31 106.5 1.9 2.4e-30 105.2 0.2 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) T4SS PF07996.6 AEO57927.1 - 0.063 13.1 0.5 0.13 12.1 0.4 1.4 1 0 0 1 1 1 0 Type IV secretion system proteins zf-CCHC PF00098.18 AEO57928.1 - 0.00014 21.6 3.3 0.00022 21.0 2.3 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 AEO57928.1 - 0.01 15.3 0.7 0.018 14.5 0.5 1.4 1 0 0 1 1 1 1 Zinc knuckle DUF2397 PF09660.5 AEO57928.1 - 0.71 8.3 10.7 2.7 6.4 2.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2397) CDC45 PF02724.9 AEO57928.1 - 2.1 6.2 13.7 0.27 9.2 6.8 1.4 2 0 0 2 2 2 0 CDC45-like protein SEEEED PF14797.1 AEO57928.1 - 2.6 8.1 28.9 0.068 13.3 15.0 1.9 2 0 0 2 2 2 0 Serine-rich region of AP3B1, clathrin-adaptor complex RAP1 PF07218.6 AEO57928.1 - 4.5 5.2 5.9 6.4 4.7 4.1 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) zf-CHCC PF10276.4 AEO57929.1 - 8.4e-17 60.7 1.2 1.2e-16 60.2 0.8 1.3 1 0 0 1 1 1 1 Zinc-finger domain COX5B PF01215.14 AEO57929.1 - 0.032 13.8 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Vb Methyltransf_18 PF12847.2 AEO57932.1 - 8.9e-18 64.9 0.9 1.8e-17 63.9 0.6 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO57932.1 - 4.4e-12 45.8 0.0 2.2e-09 37.0 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 AEO57932.1 - 2.4e-08 34.0 0.0 6.4e-08 32.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO57932.1 - 8.2e-07 29.4 0.7 3.8e-05 24.0 0.5 2.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO57932.1 - 4.6e-06 26.9 0.1 2.6e-05 24.4 0.0 2.3 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO57932.1 - 1.1e-05 25.2 2.8 4e-05 23.3 1.9 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO57932.1 - 2e-05 24.9 0.3 0.00018 21.9 0.0 2.5 3 0 0 3 3 2 1 Methyltransferase domain AdoMet_MTase PF07757.8 AEO57932.1 - 0.00034 20.6 0.0 0.00059 19.9 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase MTS PF05175.9 AEO57932.1 - 0.00057 19.2 0.0 0.00094 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.7 AEO57932.1 - 0.00087 18.7 0.0 0.0017 17.7 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 AEO57932.1 - 0.0035 17.0 0.0 0.0054 16.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 AEO57932.1 - 0.046 12.7 0.0 0.072 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Daxx PF03344.10 AEO57932.1 - 0.28 9.6 5.4 0.34 9.3 3.8 1.1 1 0 0 1 1 1 0 Daxx Family HTH_AsnC-type PF13404.1 AEO57932.1 - 0.61 9.6 3.6 1.7 8.2 2.5 1.8 1 1 0 1 1 1 0 AsnC-type helix-turn-helix domain FAM176 PF14851.1 AEO57932.1 - 0.91 9.2 3.3 1.9 8.1 2.3 1.5 1 0 0 1 1 1 0 FAM176 family Nop14 PF04147.7 AEO57932.1 - 0.97 7.2 7.6 1.2 6.9 5.3 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 AEO57932.1 - 3.1 6.9 5.1 5.3 6.2 3.5 1.3 1 0 0 1 1 1 0 NOA36 protein HEAT PF02985.17 AEO57933.1 - 4.8e-44 144.5 15.0 0.0054 16.7 0.0 13.2 14 0 0 14 14 14 10 HEAT repeat HEAT_2 PF13646.1 AEO57933.1 - 3.8e-30 104.0 5.8 1.1e-06 28.7 0.0 7.8 3 3 5 8 8 8 8 HEAT repeats HEAT_EZ PF13513.1 AEO57933.1 - 6.4e-12 45.5 9.9 0.032 14.7 0.0 9.0 8 2 3 11 11 11 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 AEO57933.1 - 6.7e-11 42.4 5.2 0.04 14.3 0.1 7.4 5 2 4 9 9 8 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 AEO57933.1 - 4.6e-10 38.4 5.3 0.00035 19.0 0.2 4.6 3 1 1 4 4 4 3 Adaptin N terminal region CLASP_N PF12348.3 AEO57933.1 - 7.2e-05 22.2 1.6 5 6.4 0.0 4.7 4 3 2 6 6 6 3 CLASP N terminal DUF2435 PF10363.4 AEO57933.1 - 8.3e-05 22.4 4.3 0.035 13.9 0.2 4.1 3 0 0 3 3 3 1 Protein of unknown function (DUF2435) Arm PF00514.18 AEO57933.1 - 0.0041 16.8 3.4 1.9 8.4 0.0 5.3 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat Cnd1 PF12717.2 AEO57933.1 - 0.023 14.5 7.6 4.4 7.1 0.1 5.6 6 1 1 7 7 7 0 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.2 AEO57933.1 - 0.029 13.3 0.9 0.4 9.6 0.1 2.8 3 1 1 4 4 4 0 Nuclear condensing complex subunits, C-term domain Ecm29 PF13001.2 AEO57933.1 - 0.07 11.6 1.0 7.7 4.8 0.1 3.1 3 0 0 3 3 3 0 Proteasome stabiliser MadL PF03817.8 AEO57933.1 - 0.093 12.5 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Malonate transporter MadL subunit Proteasom_PSMB PF10508.4 AEO57933.1 - 0.34 9.1 3.0 0.59 8.3 0.0 2.4 3 0 0 3 3 3 0 Proteasome non-ATPase 26S subunit Myotub-related PF06602.9 AEO57934.1 - 1.4e-125 418.7 0.0 2.1e-125 418.1 0.0 1.3 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 AEO57934.1 - 0.0083 16.3 0.0 0.032 14.4 0.0 2.0 1 0 0 1 1 1 1 Tyrosine phosphatase family G-alpha PF00503.15 AEO57934.1 - 0.12 11.0 0.1 0.2 10.3 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit Y_phosphatase PF00102.22 AEO57934.1 - 0.2 10.9 0.0 0.35 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Ribosomal_S3_C PF00189.15 AEO57935.1 - 1.3e-16 60.5 0.1 2.6e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 AEO57935.1 - 2.6e-12 46.1 0.1 4.6e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 AEO57935.1 - 0.059 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Mg_trans_NIPA PF05653.9 AEO57936.1 - 1.1e-103 346.3 13.6 1.4e-103 346.0 9.4 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 AEO57936.1 - 9.1e-09 35.5 3.7 9.1e-09 35.5 2.5 3.4 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 AEO57936.1 - 2.1e-05 24.5 8.8 2.1e-05 24.5 6.1 2.9 2 1 1 3 3 3 2 EamA-like transporter family DUF1282 PF06930.7 AEO57936.1 - 0.51 9.9 14.4 4.7 6.8 0.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1282) DUF2420 PF10336.4 AEO57937.1 - 0.055 13.0 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2420) Adap_comp_sub PF00928.16 AEO57938.1 - 3.3e-19 69.0 0.1 4.8e-19 68.4 0.1 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 AEO57938.1 - 3.8e-08 33.1 0.1 6.6e-08 32.3 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Apc4 PF12896.2 AEO57939.1 - 4.7e-58 195.9 0.0 6.9e-58 195.4 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 WD40 PF00400.27 AEO57939.1 - 0.054 13.4 0.0 0.24 11.3 0.0 2.1 2 0 0 2 2 2 0 WD domain, G-beta repeat PH PF00169.24 AEO57940.1 - 0.00073 19.7 0.0 0.0019 18.3 0.0 1.8 1 0 0 1 1 1 1 PH domain Sporozoite_P67 PF05642.6 AEO57940.1 - 6.3 4.5 7.5 11 3.6 5.2 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Adenylsucc_synt PF00709.16 AEO57941.1 - 3.6e-155 516.7 0.0 4.1e-155 516.5 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Mis14 PF08641.7 AEO57941.1 - 0.2 11.7 0.0 0.35 10.9 0.0 1.3 1 0 0 1 1 1 0 Kinetochore protein Mis14 like ELO PF01151.13 AEO57942.1 - 1.5e-83 279.9 10.8 1.8e-83 279.6 7.5 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF1518 PF07469.7 AEO57942.1 - 4.6 7.4 10.8 0.11 12.7 2.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1518) FYVE PF01363.16 AEO57943.1 - 2.9e-15 55.9 8.9 4.5e-15 55.3 6.2 1.3 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.11 AEO57943.1 - 1.4 8.8 16.2 0.11 12.4 7.6 1.8 2 0 0 2 2 2 0 AN1-like Zinc finger Synaptobrevin PF00957.16 AEO57944.1 - 1.4e-14 53.3 0.5 2.3e-14 52.7 0.3 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 AEO57944.1 - 2.8e-13 49.2 0.0 7.9e-13 47.7 0.0 1.8 1 1 0 1 1 1 1 Regulated-SNARE-like domain Staphylokinase PF02821.11 AEO57944.1 - 0.048 13.4 0.1 0.072 12.8 0.1 1.4 1 0 0 1 1 1 0 Staphylokinase/Streptokinase family TFR_dimer PF04253.10 AEO57944.1 - 0.11 12.0 0.2 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 Transferrin receptor-like dimerisation domain MoaC PF01967.16 AEO57945.1 - 1e-49 167.7 0.0 1.9e-49 166.8 0.0 1.5 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.8 AEO57945.1 - 5.4e-34 116.6 0.0 1.6e-33 115.0 0.0 1.8 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 AEO57945.1 - 2.5e-18 66.7 0.0 4.1e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 AEO57945.1 - 8.1e-05 22.7 0.0 0.00017 21.7 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 AEO57945.1 - 0.00047 20.1 0.0 0.0012 18.8 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain WD40 PF00400.27 AEO57946.1 - 3.4e-06 26.7 7.2 10 6.1 0.0 7.3 7 0 0 7 7 7 2 WD domain, G-beta repeat IKI3 PF04762.7 AEO57946.1 - 0.019 12.8 0.0 1.6 6.4 0.0 2.4 2 1 0 2 2 2 0 IKI3 family PD40 PF07676.7 AEO57946.1 - 0.021 14.4 0.4 0.38 10.4 0.0 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat RRM_6 PF14259.1 AEO57947.1 - 8e-12 44.9 0.0 3e-07 30.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AEO57947.1 - 9.3e-11 41.2 0.0 5.5e-05 22.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO57947.1 - 0.00079 19.2 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lebercilin PF15619.1 AEO57948.1 - 0.0011 18.3 3.1 0.0016 17.9 2.2 1.2 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease DUF842 PF05811.8 AEO57948.1 - 0.0039 16.6 0.1 0.0055 16.1 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) Rabaptin PF03528.10 AEO57948.1 - 0.015 15.1 0.2 0.018 14.9 0.2 1.3 1 0 0 1 1 1 0 Rabaptin DUF4510 PF14971.1 AEO57948.1 - 0.025 14.7 0.5 0.034 14.3 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) DUF4463 PF14703.1 AEO57948.1 - 0.055 13.9 2.7 0.077 13.5 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4463) NARP1 PF12569.3 AEO57948.1 - 0.11 11.1 6.8 0.14 10.8 4.7 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 THOC7 PF05615.8 AEO57948.1 - 0.13 12.4 3.3 0.19 12.0 2.3 1.2 1 0 0 1 1 1 0 Tho complex subunit 7 Herpes_DNAp_acc PF04929.7 AEO57948.1 - 1.4 7.8 6.0 1.6 7.5 4.2 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF4140 PF13600.1 AEO57948.1 - 1.6 9.2 5.2 1.9 9.0 3.0 1.6 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF3535 PF12054.3 AEO57949.1 - 3.7e-154 513.6 0.1 5.1e-153 509.8 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 AEO57949.1 - 3.2e-72 242.8 0.0 4.8e-72 242.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HEAT PF02985.17 AEO57949.1 - 1.2e-14 53.0 7.6 0.14 12.2 0.0 9.4 9 0 0 9 9 9 5 HEAT repeat Helicase_C PF00271.26 AEO57949.1 - 3.8e-14 52.3 0.0 8.7e-14 51.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Vac14_Fab1_bd PF12755.2 AEO57949.1 - 1.4e-06 28.5 0.6 0.14 12.5 0.0 3.9 3 0 0 3 3 3 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 AEO57949.1 - 0.042 13.2 0.2 5.5 6.2 0.1 3.3 4 0 0 4 4 4 0 CLASP N terminal SMC_N PF02463.14 AEO57950.1 - 3.4e-66 222.6 0.0 5.3e-66 222.0 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 AEO57950.1 - 2.1e-26 92.2 0.0 1.3e-25 89.6 0.0 2.5 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 AEO57950.1 - 7.5e-16 58.9 2.0 2.5e-07 30.9 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.1 AEO57950.1 - 2.7e-14 53.9 27.9 2.7e-14 53.9 19.3 7.5 2 2 3 5 5 5 1 AAA domain AAA_15 PF13175.1 AEO57950.1 - 6.8e-09 35.2 24.4 8e-06 25.1 5.7 3.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 AEO57950.1 - 0.00043 19.7 0.0 0.0011 18.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Enkurin PF13864.1 AEO57950.1 - 0.0063 16.7 3.2 0.0063 16.7 2.2 9.6 6 3 3 9 9 9 1 Calmodulin-binding ABC_tran PF00005.22 AEO57950.1 - 0.35 11.1 0.0 0.35 11.1 0.0 7.2 3 2 0 3 3 3 0 ABC transporter Reo_sigmaC PF04582.7 AEO57950.1 - 0.48 9.5 22.1 0.25 10.4 0.9 4.7 4 1 0 5 5 5 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 AEO57950.1 - 4.6 5.5 95.2 1 7.7 0.0 6.1 3 2 2 5 5 5 0 AAA domain CDC37_N PF03234.9 AEO57951.1 - 4.9e-61 206.1 5.6 4.9e-61 206.1 3.9 3.0 2 1 1 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 AEO57951.1 - 5.1e-44 149.7 1.0 2.2e-43 147.7 0.0 2.3 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 AEO57951.1 - 1.6e-24 85.6 7.2 1.6e-24 85.6 5.0 2.2 2 1 0 2 2 2 1 Cdc37 C terminal domain DUF1268 PF06896.6 AEO57951.1 - 0.0096 16.2 1.4 0.0096 16.2 1.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1268) DUF155 PF02582.9 AEO57953.1 - 1.9e-55 187.4 0.3 2.7e-55 186.9 0.2 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 HMG_box PF00505.14 AEO57954.1 - 1.4e-09 38.0 0.4 3.7e-09 36.7 0.3 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 AEO57954.1 - 3e-08 33.8 1.2 3e-08 33.8 0.8 3.0 3 1 1 4 4 4 1 HMG-box domain HHA PF05321.6 AEO57954.1 - 0.17 12.0 2.7 1.9 8.7 0.2 2.5 2 0 0 2 2 2 0 Haemolysin expression modulating protein HD-ZIP_N PF04618.7 AEO57954.1 - 0.64 10.5 0.0 0.64 10.5 0.0 2.7 2 1 0 2 2 2 0 HD-ZIP protein N terminus Asp-B-Hydro_N PF05279.6 AEO57954.1 - 3.2 7.5 27.2 0.81 9.4 16.4 1.7 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region Cpn60_TCP1 PF00118.19 AEO57955.1 - 4.8e-138 460.8 6.6 5.4e-138 460.6 4.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PP1_inhibitor PF05361.7 AEO57955.1 - 0.0066 16.1 0.6 0.022 14.4 0.4 1.9 1 1 0 1 1 1 1 PKC-activated protein phosphatase-1 inhibitor PH_10 PF15411.1 AEO57957.1 - 2e-28 98.9 0.1 3.1e-28 98.2 0.1 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain VWA_3 PF13768.1 AEO57957.1 - 1.1e-10 41.4 0.0 2.8e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 AEO57957.1 - 1.6e-07 31.1 0.1 2.7e-07 30.4 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-RING_2 PF13639.1 AEO57957.1 - 7.2e-07 28.9 5.1 1.3e-06 28.0 3.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 AEO57957.1 - 0.0027 17.3 4.3 0.0045 16.6 3.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 AEO57957.1 - 0.0039 16.8 1.8 0.0064 16.1 1.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 AEO57957.1 - 0.018 15.1 1.4 0.036 14.1 1.0 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 AEO57957.1 - 0.022 14.7 3.9 0.039 13.9 2.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C4_Topoisom PF01396.14 AEO57957.1 - 0.08 12.4 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger zf-C3HC4 PF00097.20 AEO57957.1 - 0.1 12.3 3.6 0.18 11.4 2.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1147 PF06615.6 AEO57957.1 - 0.13 12.0 0.4 0.35 10.7 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1147) zf-RING-like PF08746.6 AEO57957.1 - 0.8 9.7 3.9 1.5 8.8 2.7 1.4 1 0 0 1 1 1 0 RING-like domain MFS_1 PF07690.11 AEO57958.1 - 5.3e-23 81.2 42.6 3e-22 78.8 28.1 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1465 PF07323.7 AEO57958.1 - 0.078 12.5 0.1 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) DUF1700 PF08006.6 AEO57958.1 - 0.55 9.5 5.8 0.38 10.0 0.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) Saccharop_dh PF03435.13 AEO57959.1 - 7e-14 51.6 0.0 1.2e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase DUF3357 PF11837.3 AEO57959.1 - 0.08 12.7 0.8 0.29 11.0 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) Semialdhyde_dh PF01118.19 AEO57959.1 - 0.13 12.6 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Ribosomal_L37ae PF01780.14 AEO57960.1 - 1.7e-39 133.5 8.3 1.9e-39 133.3 5.8 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 AEO57960.1 - 0.002 17.8 3.2 0.003 17.3 2.2 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Thymidylat_synt PF00303.14 AEO57960.1 - 0.013 14.5 0.0 0.016 14.2 0.0 1.1 1 0 0 1 1 1 0 Thymidylate synthase zf-H2C2_2 PF13465.1 AEO57960.1 - 0.022 15.0 1.6 0.58 10.5 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger double domain A2L_zn_ribbon PF08792.5 AEO57960.1 - 0.034 13.5 4.1 0.94 9.0 0.1 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain Zn-ribbon_8 PF09723.5 AEO57960.1 - 0.041 13.8 1.8 0.24 11.3 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain GCC2_GCC3 PF07699.8 AEO57960.1 - 0.047 13.2 0.7 0.07 12.7 0.5 1.3 1 0 0 1 1 1 0 GCC2 and GCC3 NCD3G PF07562.9 AEO57960.1 - 0.05 13.3 1.7 0.075 12.7 1.2 1.3 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR OrfB_Zn_ribbon PF07282.6 AEO57960.1 - 0.072 12.7 1.3 0.1 12.2 0.9 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-BED PF02892.10 AEO57960.1 - 0.14 11.9 6.7 2 8.2 0.5 2.3 1 1 1 2 2 2 0 BED zinc finger Sgf11 PF08209.6 AEO57960.1 - 0.15 11.3 0.8 0.96 8.8 0.0 2.1 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Elf1 PF05129.8 AEO57960.1 - 0.16 11.6 4.0 0.3 10.8 2.8 1.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like NOB1_Zn_bind PF08772.6 AEO57960.1 - 0.22 11.3 4.7 1.1 9.0 3.1 2.1 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like zf-C2H2 PF00096.21 AEO57960.1 - 0.65 10.4 3.5 2.4 8.6 0.2 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type Tnp_zf-ribbon_2 PF13842.1 AEO57960.1 - 7.7 7.0 7.3 56 4.2 4.9 2.3 1 1 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon zf-RING_2 PF13639.1 AEO57961.1 - 1.4e-09 37.5 19.2 3.9e-09 36.1 0.7 3.7 3 1 0 3 3 3 1 Ring finger domain PHD PF00628.24 AEO57961.1 - 3.7e-09 36.1 8.1 3.7e-09 36.1 5.6 2.8 2 1 0 2 2 2 1 PHD-finger zf-rbx1 PF12678.2 AEO57961.1 - 1.9e-07 31.0 15.0 4.3e-05 23.5 3.8 3.2 2 1 0 2 2 2 2 RING-H2 zinc finger zf-Apc11 PF12861.2 AEO57961.1 - 1.4e-06 28.0 10.7 0.00088 19.0 0.9 2.4 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 AEO57961.1 - 3.2e-05 23.5 1.1 3.2e-05 23.5 0.8 3.5 3 1 1 4 4 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 AEO57961.1 - 4.9e-05 22.9 1.7 4.9e-05 22.9 1.2 3.7 3 1 1 4 4 3 1 Zinc finger, C3HC4 type (RING finger) PHD_2 PF13831.1 AEO57961.1 - 8.9e-05 21.7 1.7 8.9e-05 21.7 1.2 2.0 2 0 0 2 2 2 1 PHD-finger zf-C3HC4_2 PF13923.1 AEO57961.1 - 0.0004 20.3 1.5 0.0004 20.3 1.0 3.7 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AEO57961.1 - 0.0016 18.0 4.1 0.0016 18.0 2.9 3.3 2 2 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.1 AEO57961.1 - 0.0069 16.0 2.9 0.0069 16.0 2.0 3.1 4 1 0 4 4 3 1 Prokaryotic RING finger family 1 zf-RING_4 PF14570.1 AEO57961.1 - 0.99 9.0 5.4 0.25 10.9 0.4 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-PHD-like PF15446.1 AEO57961.1 - 4.5 6.5 11.5 0.04 13.2 1.1 2.6 3 1 1 4 4 4 0 PHD/FYVE-zinc-finger like domain DZR PF12773.2 AEO57961.1 - 4.9 7.0 10.8 9.3 6.1 1.9 3.1 3 1 0 3 3 3 0 Double zinc ribbon zf-RING_UBOX PF13445.1 AEO57961.1 - 8.2 6.2 8.8 2.4 7.9 0.1 3.2 3 0 0 3 3 3 0 RING-type zinc-finger MRP-L46 PF11788.3 AEO57962.1 - 9e-32 110.0 0.2 1.4e-31 109.4 0.1 1.3 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 AEO57962.1 - 8.1e-06 25.5 0.0 1.7e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Cytochrom_B561 PF03188.11 AEO57965.1 - 6.9e-06 25.9 8.3 1.2e-05 25.1 5.8 1.3 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2076 PF09849.4 AEO57965.1 - 0.012 15.6 0.1 0.028 14.4 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF2427 PF10348.4 AEO57965.1 - 0.023 14.2 2.8 0.054 13.0 1.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) MerC PF03203.9 AEO57965.1 - 3.5 8.0 0.0 3.5 8.0 0.0 3.1 2 1 1 3 3 3 0 MerC mercury resistance protein Nnf1 PF03980.9 AEO57966.1 - 2.5e-25 88.5 9.8 3.7e-25 88.0 0.8 3.5 4 0 0 4 4 4 2 Nnf1 DUF4164 PF13747.1 AEO57966.1 - 2.5 8.2 8.1 0.67 10.1 2.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) TPR_MLP1_2 PF07926.7 AEO57966.1 - 3 7.6 7.3 0.12 12.0 0.2 2.2 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein PH_9 PF15410.1 AEO57967.1 - 1.3e-09 38.2 0.0 2.3e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain YonK PF09642.5 AEO57967.1 - 0.0086 15.7 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 YonK protein NTF2 PF02136.15 AEO57968.1 - 2.7e-23 82.6 0.7 4.5e-23 81.8 0.5 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 AEO57968.1 - 4.4e-09 35.8 0.2 8.3e-09 34.9 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO57968.1 - 1.8e-06 27.8 0.2 3.9e-06 26.7 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 AEO57968.1 - 0.00011 21.9 0.6 0.00036 20.3 0.0 2.2 2 0 0 2 2 2 1 RNA binding motif RRM_5 PF13893.1 AEO57968.1 - 0.0014 18.4 0.1 0.0028 17.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF605 PF04652.11 AEO57968.1 - 1.6 8.0 36.2 0.15 11.4 22.1 1.4 2 0 0 2 2 2 0 Vta1 like PAT1 PF09770.4 AEO57968.1 - 5.5 5.0 29.1 7.1 4.7 20.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Acyltransferase PF01553.16 AEO57969.1 - 4.5e-14 52.0 0.0 6.8e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase zf-C3HC4_2 PF13923.1 AEO57970.1 - 1e-08 35.0 16.7 2.4e-05 24.2 5.4 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO57970.1 - 8.2e-07 28.6 6.2 8.2e-07 28.6 4.3 2.8 2 2 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 AEO57970.1 - 6.1e-06 25.8 13.9 2.3e-05 23.9 4.3 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AEO57970.1 - 9.3e-06 25.3 12.6 0.00014 21.5 4.1 2.6 2 0 0 2 2 2 2 Ring finger domain zf-RING_UBOX PF13445.1 AEO57970.1 - 4.6e-05 23.0 5.2 4.6e-05 23.0 3.6 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 AEO57970.1 - 9.2e-05 22.2 17.2 0.00014 21.6 5.6 2.6 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 AEO57970.1 - 0.00034 20.1 6.8 0.00034 20.1 4.7 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 AEO57970.1 - 0.00041 19.6 4.1 0.00041 19.6 2.8 2.8 1 1 2 3 3 2 1 Rtf2 RING-finger FYVE PF01363.16 AEO57970.1 - 0.0031 17.3 12.5 0.015 15.1 3.8 3.1 2 1 1 3 3 3 2 FYVE zinc finger zf-TFIIIC PF12660.2 AEO57970.1 - 0.014 15.3 4.3 1.5 8.7 0.2 2.3 2 0 0 2 2 2 0 Putative zinc-finger of transcription factor IIIC complex Rad50_zn_hook PF04423.9 AEO57970.1 - 0.034 13.6 0.2 0.034 13.6 0.1 3.0 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-rbx1 PF12678.2 AEO57970.1 - 3.6 7.7 6.7 2.8 8.1 2.1 2.5 1 1 1 2 2 2 0 RING-H2 zinc finger Zn-ribbon_8 PF09723.5 AEO57970.1 - 4.1 7.4 9.3 9.6 6.2 0.1 3.1 3 0 0 3 3 3 0 Zinc ribbon domain Mito_carr PF00153.22 AEO57971.1 - 2.4e-09 36.7 0.1 2.4e-09 36.7 0.1 2.0 2 0 0 2 2 2 1 Mitochondrial carrier protein MIP-T3 PF10243.4 AEO57971.1 - 0.2 10.0 20.9 0.31 9.4 14.5 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SCA7 PF08313.7 AEO57972.1 - 1.5e-34 117.4 0.4 5.3e-34 115.6 0.3 1.9 1 0 0 1 1 1 1 SCA7, zinc-binding domain Sgf11 PF08209.6 AEO57972.1 - 0.014 14.6 0.7 0.025 13.8 0.5 1.4 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) zf-BED PF02892.10 AEO57972.1 - 0.098 12.4 0.2 0.23 11.2 0.1 1.5 1 0 0 1 1 1 0 BED zinc finger Glypican PF01153.14 AEO57972.1 - 2.4 6.6 5.4 4.2 5.8 3.7 1.3 1 0 0 1 1 1 0 Glypican Pkinase PF00069.20 AEO57973.1 - 4.8e-76 255.3 0.0 5.5e-76 255.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO57973.1 - 4.2e-38 130.9 0.0 5.3e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO57973.1 - 0.0075 15.2 0.0 0.022 13.7 0.0 1.7 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 AEO57973.1 - 0.032 13.2 0.0 0.052 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AEO57973.1 - 0.034 13.8 0.2 0.17 11.5 0.0 2.1 3 0 0 3 3 3 0 Phosphotransferase enzyme family Peptidase_M28 PF04389.12 AEO57974.1 - 3.2e-39 134.5 0.0 4.9e-39 133.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Dynamin_N PF00350.18 AEO57976.1 - 1.3e-17 64.1 3.8 3.1e-17 62.9 0.0 3.4 3 2 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 AEO57976.1 - 1.7e-05 24.7 0.0 0.0038 17.1 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.22 AEO57976.1 - 0.00081 19.6 0.3 0.0036 17.6 0.0 2.3 2 0 0 2 2 2 1 ABC transporter Zeta_toxin PF06414.7 AEO57976.1 - 0.0043 16.1 1.1 0.025 13.6 0.0 2.9 3 0 0 3 3 3 1 Zeta toxin DUF258 PF03193.11 AEO57976.1 - 0.0045 16.1 0.0 0.021 14.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Vps51 PF08700.6 AEO57976.1 - 0.0051 16.6 14.9 0.58 10.0 1.1 4.7 5 0 0 5 5 4 2 Vps51/Vps67 Miro PF08477.8 AEO57976.1 - 0.023 15.2 0.0 0.071 13.5 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein AIG1 PF04548.11 AEO57976.1 - 0.026 13.6 0.0 0.097 11.7 0.0 1.9 2 0 0 2 2 2 0 AIG1 family AAA_29 PF13555.1 AEO57976.1 - 0.049 13.1 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 AEO57976.1 - 0.16 12.8 3.3 0.48 11.2 0.0 3.2 2 1 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.10 AEO57976.1 - 0.17 10.4 0.0 0.37 9.3 0.0 1.5 1 0 0 1 1 1 0 Adenovirus IVa2 protein Phlebovirus_NSM PF07246.6 AEO57976.1 - 0.21 10.7 5.7 0.29 10.2 1.1 2.4 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M AAA_22 PF13401.1 AEO57976.1 - 0.29 11.2 4.2 8 6.6 0.0 3.7 3 1 0 3 3 3 0 AAA domain COG2 PF06148.6 AEO57976.1 - 0.61 9.9 13.7 1.9 8.3 0.1 4.5 4 0 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 AAA_16 PF13191.1 AEO57976.1 - 1 9.2 7.3 1.6 8.6 0.0 3.6 4 1 0 4 4 3 0 AAA ATPase domain DUF2730 PF10805.3 AEO57976.1 - 1.7 8.4 5.7 6.5 6.5 1.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) DUF972 PF06156.8 AEO57976.1 - 2.1 8.7 14.4 1.3 9.4 0.2 4.3 3 1 1 4 4 4 0 Protein of unknown function (DUF972) AAA_13 PF13166.1 AEO57976.1 - 3.3 6.0 18.2 2.5 6.4 6.2 3.2 3 0 0 3 3 3 0 AAA domain Bacillus_HBL PF05791.6 AEO57976.1 - 7.3 5.9 11.9 7.4 5.8 0.1 3.7 4 0 0 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) ATG16 PF08614.6 AEO57976.1 - 7.4 6.3 21.5 2.8 7.7 3.1 3.5 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) Baculo_PEP_C PF04513.7 AEO57976.1 - 8.7 6.1 9.3 23 4.7 0.3 3.8 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus NUDIX_2 PF13869.1 AEO57977.1 - 2.2e-81 271.7 0.0 2.6e-81 271.4 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase DUF4316 PF14195.1 AEO57977.1 - 0.08 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4316) UPF0047 PF01894.12 AEO57978.1 - 7.7e-41 138.6 0.0 8.8e-41 138.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 ABC_membrane PF00664.18 AEO57979.1 - 1.4e-84 283.8 27.8 7.4e-47 160.0 8.5 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 AEO57979.1 - 1.3e-45 155.0 1.6 5e-30 104.5 0.1 3.5 2 1 1 3 3 3 3 ABC transporter SMC_N PF02463.14 AEO57979.1 - 1.2e-09 37.6 0.0 6.3e-09 35.3 0.0 2.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 AEO57979.1 - 3.3e-06 27.2 0.7 0.1 12.5 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 AEO57979.1 - 6.1e-06 25.5 0.1 0.021 13.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 AEO57979.1 - 2.4e-05 24.2 0.2 0.31 11.0 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.1 AEO57979.1 - 9.6e-05 21.8 0.0 0.058 12.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 AEO57979.1 - 0.00017 21.0 0.5 0.73 9.4 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 AEO57979.1 - 0.00024 21.4 0.1 0.059 13.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 AEO57979.1 - 0.00049 20.5 0.1 1.5 9.3 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein AAA_21 PF13304.1 AEO57979.1 - 0.0012 18.8 0.1 1.3 8.8 0.0 3.3 3 0 0 3 3 3 1 AAA domain Dynamin_N PF00350.18 AEO57979.1 - 0.0032 17.3 0.4 0.44 10.3 0.0 2.6 2 0 0 2 2 2 1 Dynamin family AAA_30 PF13604.1 AEO57979.1 - 0.0043 16.6 0.9 3.7 7.0 0.0 3.2 2 1 0 2 2 2 1 AAA domain DUF87 PF01935.12 AEO57979.1 - 0.017 14.9 0.4 0.66 9.7 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 T2SE PF00437.15 AEO57979.1 - 0.051 12.4 0.2 0.37 9.6 0.2 2.3 2 1 0 2 2 2 0 Type II/IV secretion system protein GTP_EFTU PF00009.22 AEO57979.1 - 0.052 12.9 0.0 4.8 6.5 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 AEO57979.1 - 0.055 13.6 1.1 5.3 7.1 0.0 3.2 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 AEO57979.1 - 0.064 12.7 0.0 3.4 7.0 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zeta_toxin PF06414.7 AEO57979.1 - 0.1 11.6 0.0 13 4.8 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin NACHT PF05729.7 AEO57979.1 - 0.11 12.0 1.8 0.32 10.6 0.0 2.6 3 0 0 3 3 2 0 NACHT domain AAA_17 PF13207.1 AEO57979.1 - 0.15 12.8 0.0 12 6.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 AEO57979.1 - 0.19 11.9 0.1 10 6.3 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AIG1 PF04548.11 AEO57979.1 - 0.45 9.5 1.5 6.5 5.7 0.0 2.3 2 0 0 2 2 2 0 AIG1 family DUF3243 PF11588.3 AEO57980.1 - 0.037 14.0 0.0 0.081 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3243) FAM101 PF15068.1 AEO57980.1 - 6.5 6.1 7.9 0.49 9.7 1.0 2.2 1 1 0 2 2 2 0 FAM101 family DUF2431 PF10354.4 AEO57981.1 - 9.8e-51 172.0 0.0 1.5e-50 171.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) DUF1999 PF09390.5 AEO57982.1 - 0.009 15.3 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1999) ThiF PF00899.16 AEO57983.1 - 5.3e-12 45.7 0.0 9.2e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 ThiF family SSP160 PF06933.6 AEO57983.1 - 1.2 6.9 16.4 1.8 6.4 11.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 MSP1_C PF07462.6 AEO57983.1 - 1.8 6.8 2.7 2.6 6.3 1.9 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF1302 PF06980.6 AEO57984.1 - 0.025 13.1 0.0 0.038 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1302) NOA36 PF06524.7 AEO57984.1 - 0.1 11.8 0.1 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 AEO57984.1 - 0.97 8.9 3.6 0.26 10.7 0.2 1.7 2 0 0 2 2 2 0 Nucleoplasmin PBP1_TM PF14812.1 AEO57984.1 - 2.4 8.4 7.2 0.62 10.4 2.0 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal eIF-6 PF01912.13 AEO57985.1 - 9.8e-83 276.1 0.8 1.3e-82 275.7 0.6 1.2 1 0 0 1 1 1 1 eIF-6 family ERM PF00769.14 AEO57986.1 - 0.1 12.1 15.2 0.2 11.1 10.5 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family ADIP PF11559.3 AEO57986.1 - 0.41 10.5 3.5 0.75 9.6 1.5 1.9 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding FUSC PF04632.7 AEO57986.1 - 9.5 4.5 17.0 16 3.7 11.8 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family NDUF_B12 PF08122.7 AEO57987.1 - 6.4e-18 64.2 3.6 9.9e-18 63.6 2.5 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family CAF1 PF04857.15 AEO57988.1 - 3.2e-69 233.2 0.2 8e-69 231.8 0.0 1.8 2 0 0 2 2 2 1 CAF1 family ribonuclease Suf PF05843.9 AEO57988.1 - 0.091 12.4 10.1 5.2 6.7 4.9 2.4 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) RFX_DNA_binding PF02257.10 AEO57988.1 - 0.19 11.8 0.0 0.19 11.8 0.0 1.9 2 0 0 2 2 2 0 RFX DNA-binding domain RR_TM4-6 PF06459.7 AEO57988.1 - 0.36 10.6 3.9 0.4 10.5 0.3 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Raftlin PF15250.1 AEO57988.1 - 5.8 5.3 11.5 0.91 7.9 2.8 2.2 2 0 0 2 2 2 0 Raftlin CLTH PF10607.4 AEO57989.1 - 9.5e-42 142.1 0.3 1.4e-41 141.5 0.2 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 AEO57989.1 - 0.055 13.2 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 LisH HLH PF00010.21 AEO57990.1 - 2.9e-12 46.0 0.2 6.6e-12 44.9 0.2 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DivIC PF04977.10 AEO57990.1 - 0.074 12.5 1.8 0.16 11.4 1.3 1.6 1 0 0 1 1 1 0 Septum formation initiator Snapin_Pallidin PF14712.1 AEO57990.1 - 0.1 12.9 2.0 0.19 12.0 1.4 1.5 1 0 0 1 1 1 0 Snapin/Pallidin TSC22 PF01166.13 AEO57990.1 - 0.11 12.5 0.5 0.11 12.5 0.3 2.0 2 0 0 2 2 2 0 TSC-22/dip/bun family bZIP_Maf PF03131.12 AEO57990.1 - 4.7 7.5 7.7 0.63 10.3 1.4 2.3 2 0 0 2 2 2 0 bZIP Maf transcription factor Aminotran_3 PF00202.16 AEO57991.1 - 3.6e-95 318.6 0.0 4.2e-95 318.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 AEO57991.1 - 0.2 10.5 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II SET PF00856.23 AEO57992.1 - 1.4e-21 77.4 0.2 1.4e-21 77.4 0.1 3.1 2 2 0 2 2 2 1 SET domain SRI PF08236.6 AEO57992.1 - 1.6e-18 66.3 5.8 3.7e-18 65.2 4.0 1.6 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain WW PF00397.21 AEO57992.1 - 3.1e-06 26.9 1.8 6.5e-06 25.8 1.2 1.6 1 0 0 1 1 1 1 WW domain Med26 PF08711.6 AEO57992.1 - 0.00092 18.6 0.0 0.0026 17.2 0.0 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Terpene_synth PF01397.16 AEO57992.1 - 0.046 13.0 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain AT_hook PF02178.14 AEO57993.1 - 0.036 13.7 3.3 0.13 12.0 2.3 2.0 1 0 0 1 1 1 0 AT hook motif HNH_2 PF13391.1 AEO57994.1 - 0.14 11.9 0.1 0.65 9.8 0.0 2.1 2 0 0 2 2 2 0 HNH endonuclease XPC-binding PF09280.6 AEO57995.1 - 8.6e-25 85.9 10.5 1.6e-24 85.1 7.3 1.4 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.18 AEO57995.1 - 3.8e-18 64.6 0.5 6.1e-18 63.9 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 AEO57995.1 - 3.4e-15 55.3 3.9 4.5e-08 32.6 0.1 2.7 2 0 0 2 2 2 2 UBA/TS-N domain Rad60-SLD PF11976.3 AEO57995.1 - 1.5e-09 37.3 0.4 2.9e-09 36.4 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 AEO57995.1 - 0.0024 18.0 0.0 0.0054 16.8 0.0 1.7 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 AEO57995.1 - 0.015 15.1 0.0 0.04 13.8 0.0 1.7 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.5 AEO57995.1 - 0.02 14.4 0.0 2.2 7.9 0.0 2.4 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain MCM_N PF14551.1 AEO57995.1 - 0.022 15.2 0.1 0.056 13.9 0.0 1.6 1 0 0 1 1 1 0 MCM N-terminal domain eIF-5a PF01287.15 AEO57995.1 - 0.093 12.6 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold FAP PF07174.6 AEO57995.1 - 9.3 5.4 28.0 0.36 10.0 15.3 1.5 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) Myb_DNA-binding PF00249.26 AEO57996.1 - 4.2e-10 39.5 0.0 7.5e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 AEO57996.1 - 0.00027 20.9 0.0 0.00071 19.6 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain PRA-PH PF01503.12 AEO57996.1 - 0.19 12.0 0.0 0.19 12.0 0.0 2.4 2 1 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase Complex1_LYR_2 PF13233.1 AEO57996.1 - 0.21 12.0 3.7 0.66 10.4 0.1 2.1 2 0 0 2 2 2 0 Complex1_LYR-like BRE1 PF08647.6 AEO57997.1 - 1.8e-30 104.7 7.8 1.8e-30 104.7 5.4 6.1 4 1 1 5 5 4 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.1 AEO57997.1 - 8.9e-09 35.2 9.0 1.5e-08 34.5 6.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AEO57997.1 - 1.8e-08 33.8 7.6 3.2e-08 33.1 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AEO57997.1 - 2.6e-07 30.1 8.2 4.7e-07 29.3 5.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO57997.1 - 3.6e-07 29.7 9.7 6.2e-07 29.0 6.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 AEO57997.1 - 1.7e-06 27.7 6.9 2.9e-06 26.9 4.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_6 PF14835.1 AEO57997.1 - 7.2e-05 22.4 4.6 0.00017 21.3 3.2 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 AEO57997.1 - 0.00022 20.8 4.7 0.00058 19.5 3.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.1 AEO57997.1 - 0.00081 18.8 2.6 0.0015 18.0 1.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Reo_sigmaC PF04582.7 AEO57997.1 - 0.0022 17.2 1.8 0.0022 17.2 1.2 3.9 4 1 0 4 4 4 2 Reovirus sigma C capsid protein zf-C3HC4_4 PF15227.1 AEO57997.1 - 0.0095 15.8 6.5 0.018 14.8 4.5 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 AEO57997.1 - 0.074 12.6 6.5 0.29 10.7 4.6 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain DUF1192 PF06698.6 AEO57997.1 - 1.7 8.5 21.9 0.37 10.6 0.1 5.8 4 1 1 5 5 5 0 Protein of unknown function (DUF1192) DUF1183 PF06682.7 AEO57998.1 - 2.3e-67 227.8 16.4 6.8e-67 226.3 11.4 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1183) ATG27 PF09451.5 AEO57998.1 - 0.058 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Autophagy-related protein 27 ABC_membrane PF00664.18 AEO57999.1 - 2.4e-96 322.3 41.8 2.7e-50 171.3 11.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 AEO57999.1 - 1.9e-69 232.2 0.0 9.5e-34 116.6 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 AEO57999.1 - 5.2e-13 48.7 0.0 0.0012 18.1 0.0 3.9 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 AEO57999.1 - 6.8e-10 39.3 0.6 0.23 11.4 0.0 4.4 2 2 1 3 3 3 3 AAA domain AAA_29 PF13555.1 AEO57999.1 - 5e-09 35.5 1.4 0.00028 20.3 0.2 3.3 3 0 0 3 3 3 2 P-loop containing region of AAA domain ABC_ATPase PF09818.4 AEO57999.1 - 2.9e-08 32.7 3.2 0.0038 15.8 0.1 3.1 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 AEO57999.1 - 4.8e-07 29.9 4.7 0.0012 18.9 0.0 3.7 4 1 0 4 4 3 2 AAA ATPase domain AAA_17 PF13207.1 AEO57999.1 - 2.2e-06 28.4 0.0 0.1 13.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 AEO57999.1 - 4.6e-06 25.9 0.0 0.089 11.9 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA PF00004.24 AEO57999.1 - 2.9e-05 24.2 0.7 1.3 9.2 0.0 4.4 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 AEO57999.1 - 3.3e-05 23.3 0.3 0.39 10.0 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 AEO57999.1 - 0.00023 21.2 1.4 2.6 8.1 0.0 4.0 3 1 0 3 3 3 1 AAA domain SbcCD_C PF13558.1 AEO57999.1 - 0.00031 20.6 1.4 0.83 9.6 0.1 3.5 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 AEO57999.1 - 0.0017 18.2 0.0 3 7.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 AEO57999.1 - 0.0025 17.7 0.0 5.8 6.8 0.0 3.5 3 1 0 4 4 3 0 AAA domain AAA_28 PF13521.1 AEO57999.1 - 0.003 17.5 0.4 0.55 10.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 AEO57999.1 - 0.0037 17.5 0.0 4.9 7.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 AEO57999.1 - 0.02 14.6 0.2 10 5.8 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 AEO57999.1 - 0.023 13.8 0.0 1.5 7.9 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin G-alpha PF00503.15 AEO57999.1 - 0.025 13.3 0.0 3.6 6.1 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit AAA_10 PF12846.2 AEO57999.1 - 0.028 13.8 2.8 16 4.7 0.2 3.7 4 0 0 4 4 4 0 AAA-like domain DUF815 PF05673.8 AEO57999.1 - 0.031 13.1 0.0 6.2 5.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF87 PF01935.12 AEO57999.1 - 0.034 13.9 0.4 7.3 6.3 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 AEO57999.1 - 0.039 13.9 0.2 12 5.9 0.1 2.9 2 1 0 2 2 2 0 50S ribosome-binding GTPase MobB PF03205.9 AEO57999.1 - 0.042 13.5 0.5 15 5.2 0.0 3.0 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 AEO57999.1 - 0.05 13.9 0.8 5.1 7.3 0.2 2.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 AEO57999.1 - 0.22 11.7 0.3 18 5.5 0.0 3.1 3 0 0 3 3 2 0 RNA helicase ATP-synt_ab PF00006.20 AEO57999.1 - 0.44 10.0 4.5 6.7 6.1 0.3 3.2 3 1 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain Ribosomal_L10 PF00466.15 AEO58000.1 - 9.2e-22 76.8 0.0 1.4e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 BSP_II PF05432.6 AEO58000.1 - 0.028 13.7 1.8 0.045 13.0 1.2 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) U1snRNP70_N PF12220.3 AEO58001.1 - 1.1e-34 118.6 1.8 1.9e-34 117.8 1.3 1.4 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 AEO58001.1 - 2.5e-16 59.0 0.1 1.3e-15 56.7 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO58001.1 - 9.5e-11 41.5 0.1 2e-10 40.4 0.1 1.6 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO58001.1 - 7.1e-09 35.3 0.0 1.7e-08 34.1 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) L51_S25_CI-B8 PF05047.11 AEO58002.1 - 3.8e-17 61.7 0.0 5.7e-17 61.1 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF187 PF02638.10 AEO58002.1 - 0.061 12.1 0.0 0.061 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase like GH101 TIM PF00121.13 AEO58003.1 - 3e-93 311.3 0.4 3.4e-93 311.1 0.3 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.9 AEO58003.1 - 0.078 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 CutC family U3_snoRNA_assoc PF08297.6 AEO58004.1 - 1.1e-15 57.5 2.4 1.1e-15 57.5 1.6 3.5 3 1 0 3 3 3 1 U3 snoRNA associated Prp19_bind PF06991.6 AEO58004.1 - 1.7 7.8 21.0 0.063 12.5 10.1 1.9 2 0 0 2 2 2 0 Splicing factor, Prp19-binding domain TPR_11 PF13414.1 AEO58005.1 - 9.3e-05 22.0 0.4 0.06 13.0 0.2 2.6 1 1 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 AEO58005.1 - 0.0013 18.5 1.3 0.046 13.6 0.2 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 AEO58005.1 - 0.0041 16.6 0.4 0.098 12.3 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 AEO58005.1 - 0.2 12.3 9.9 3.1 8.5 0.3 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Golgin_A5 PF09787.4 AEO58006.1 - 4.7 5.6 6.4 6.6 5.1 4.5 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Velvet PF11754.3 AEO58008.1 - 7.7e-55 185.6 0.0 7.7e-55 185.6 0.0 1.8 3 0 0 3 3 3 1 Velvet factor NOA36 PF06524.7 AEO58008.1 - 6.6 5.8 6.6 10 5.2 4.5 1.2 1 0 0 1 1 1 0 NOA36 protein Cullin PF00888.17 AEO58009.1 - 2.9e-114 382.7 0.0 4.1e-114 382.2 0.0 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 AEO58009.1 - 3.2e-26 90.9 1.0 6.3e-26 89.9 0.7 1.5 1 0 0 1 1 1 1 Cullin protein neddylation domain PQ-loop PF04193.9 AEO58010.1 - 2.9e-41 138.8 7.6 2e-20 72.0 1.2 2.7 2 0 0 2 2 2 2 PQ loop repeat MFS_1 PF07690.11 AEO58011.1 - 2.1e-11 43.1 39.1 2.1e-11 43.1 27.1 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 AEO58011.1 - 0.077 11.3 30.2 0.1 10.9 5.4 3.1 1 1 1 3 3 3 0 MFS/sugar transport protein ECH PF00378.15 AEO58012.1 - 2.1e-26 92.5 0.1 9.6e-26 90.3 0.1 1.8 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF1731 PF08338.6 AEO58012.1 - 0.027 13.9 0.1 0.16 11.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) Vps51 PF08700.6 AEO58013.1 - 1.7e-07 30.9 0.0 4.2e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Vps51/Vps67 Remorin_N PF03766.8 AEO58013.1 - 9.9 6.0 13.2 0.063 13.0 0.4 2.9 3 0 0 3 3 3 0 Remorin, N-terminal region NUDIX-like PF09296.6 AEO58014.1 - 6.8e-19 68.0 0.2 2.6e-18 66.1 0.1 2.0 3 0 0 3 3 3 1 NADH pyrophosphatase-like rudimentary NUDIX domain NUDIX PF00293.23 AEO58014.1 - 2.3e-17 62.8 0.1 4.1e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.6 AEO58014.1 - 1.5e-08 33.9 2.5 2.7e-08 33.1 1.7 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Ribosomal_L1 PF00687.16 AEO58015.1 - 6.8e-54 182.5 0.5 8.3e-54 182.2 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Zn_clus PF00172.13 AEO58016.1 - 1.5e-05 24.7 7.8 2.9e-05 23.8 5.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 AEO58018.1 - 0.0016 18.6 12.4 0.0071 16.6 0.3 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 AEO58018.1 - 0.011 16.0 4.6 0.78 10.2 0.1 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type SET PF00856.23 AEO58019.1 - 4e-13 49.9 0.0 7.4e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 SET domain SAF PF08666.7 AEO58019.1 - 0.097 13.0 0.1 4.5 7.7 0.0 2.4 2 0 0 2 2 2 0 SAF domain Sporozoite_P67 PF05642.6 AEO58019.1 - 0.25 9.1 0.1 0.35 8.6 0.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Kinetochor_Ybp2 PF08568.5 AEO58020.1 - 8.3e-94 315.0 0.0 1.1e-93 314.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin Glyco_transf_28 PF03033.15 AEO58021.1 - 3.6e-09 36.5 0.1 1e-08 35.0 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain PAN_4 PF14295.1 AEO58022.1 - 0.00029 20.4 1.9 0.00058 19.5 1.3 1.5 1 1 0 1 1 1 1 PAN domain COesterase PF00135.23 AEO58023.1 - 9.3e-81 272.1 0.0 5.1e-80 269.6 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 AEO58023.1 - 1.6e-10 40.9 0.1 5e-10 39.3 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 AEO58023.1 - 0.017 14.3 0.2 0.034 13.3 0.1 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 AEO58023.1 - 0.043 13.5 0.4 0.11 12.2 0.1 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family HeLo PF14479.1 AEO58024.1 - 2.7e-50 171.0 2.3 4.8e-50 170.2 1.6 1.4 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase_Tyr PF07714.12 AEO58024.1 - 3.4e-05 23.0 0.0 0.00012 21.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 AEO58024.1 - 8.9e-05 21.7 0.0 0.00018 20.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Zn_clus PF00172.13 AEO58025.1 - 3.7e-10 39.5 6.6 8.8e-10 38.3 4.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 AEO58025.1 - 2.9e-05 23.0 0.0 9.1e-05 21.4 0.0 1.9 2 1 0 2 2 2 1 Fungal specific transcription factor domain CH PF00307.26 AEO58026.1 - 1.3e-10 41.2 0.0 2.1e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.6 AEO58026.1 - 0.098 12.7 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 CDC24 Calponin NDUFA12 PF05071.11 AEO58027.1 - 4.5e-08 33.4 3.7 9e-07 29.3 1.0 2.6 3 0 0 3 3 3 2 NADH ubiquinone oxidoreductase subunit NDUFA12 PSCyt3 PF07627.6 AEO58029.1 - 0.085 12.7 0.1 0.089 12.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1588) DNA_pol_A PF00476.15 AEO58030.1 - 1.1e-100 336.9 0.0 2e-100 336.1 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family A zf-C3HC4_3 PF13920.1 AEO58031.1 - 7.2e-12 44.7 8.9 1e-11 44.2 6.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AEO58031.1 - 1.2e-09 37.8 10.5 1.8e-09 37.3 7.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 AEO58031.1 - 4.5e-08 32.9 10.5 6.7e-08 32.4 7.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AEO58031.1 - 7.5e-08 31.9 10.4 1.2e-07 31.2 7.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO58031.1 - 1.1e-07 31.4 9.5 1.7e-07 30.8 6.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 AEO58031.1 - 0.00019 21.1 4.1 0.00031 20.5 2.8 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 AEO58031.1 - 0.00046 19.7 5.7 0.00077 19.0 4.0 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 AEO58031.1 - 0.00049 19.9 8.0 0.00088 19.1 5.6 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 AEO58031.1 - 0.0029 17.1 7.5 0.024 14.1 5.2 2.2 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 Pox_Ag35 PF03286.9 AEO58031.1 - 0.028 13.9 5.3 0.036 13.6 3.7 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein zf-RING_UBOX PF13445.1 AEO58031.1 - 0.031 13.9 11.5 0.13 11.9 3.5 3.1 2 1 1 3 3 3 0 RING-type zinc-finger TerY-C PF15616.1 AEO58031.1 - 0.092 12.6 2.2 0.14 12.1 1.5 1.3 1 0 0 1 1 1 0 TerY-C metal binding domain zf-rbx1 PF12678.2 AEO58031.1 - 0.23 11.5 8.5 0.55 10.3 5.8 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger zf-RING_6 PF14835.1 AEO58031.1 - 0.29 10.9 4.2 0.54 10.0 2.9 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DZR PF12773.2 AEO58031.1 - 0.62 9.9 3.8 1.7 8.4 2.6 1.7 1 1 0 1 1 1 0 Double zinc ribbon UPF0547 PF10571.4 AEO58031.1 - 0.82 9.4 6.4 2.8 7.7 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 FYVE PF01363.16 AEO58031.1 - 0.87 9.5 6.9 2.5 8.0 4.7 1.9 1 1 0 1 1 1 0 FYVE zinc finger PBP1_TM PF14812.1 AEO58031.1 - 1.4 9.3 4.1 0.43 10.9 0.8 1.7 2 0 0 2 2 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOB1_Zn_bind PF08772.6 AEO58031.1 - 3.7 7.4 6.1 9 6.2 0.8 2.3 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-MIZ PF02891.15 AEO58031.1 - 5.4 6.6 8.2 10 5.7 5.7 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger DUF3414 PF11894.3 AEO58032.1 - 0 1483.3 0.0 0 1483.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) PI3_PI4_kinase PF00454.22 AEO58033.1 - 3.2e-44 151.1 0.0 6.3e-44 150.1 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 AEO58033.1 - 5.4e-33 113.9 0.0 5.2e-32 110.7 0.0 2.8 3 0 0 3 3 3 1 Telomere-length maintenance and DNA damage repair FAT PF02259.18 AEO58033.1 - 2.3e-26 92.6 10.5 5.1e-26 91.4 7.3 1.6 1 0 0 1 1 1 1 FAT domain FATC PF02260.15 AEO58033.1 - 5.3e-11 41.7 0.1 1.3e-10 40.5 0.1 1.7 1 0 0 1 1 1 1 FATC domain Connexin43 PF03508.8 AEO58033.1 - 0.2 10.9 0.7 0.49 9.6 0.5 1.6 1 0 0 1 1 1 0 Gap junction alpha-1 protein (Cx43) SNF5 PF04855.7 AEO58034.1 - 3.1e-75 252.8 0.2 4.9e-75 252.1 0.1 1.3 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 Peptidase_M24 PF00557.19 AEO58035.1 - 5.5e-10 39.1 0.0 7.1e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 BLVR PF06375.6 AEO58035.1 - 0.0054 16.5 7.0 0.01 15.6 4.8 1.5 1 0 0 1 1 1 1 Bovine leukaemia virus receptor (BLVR) PHD PF00628.24 AEO58036.1 - 3.8e-15 55.3 17.5 1.5e-09 37.3 5.8 2.4 2 0 0 2 2 2 2 PHD-finger Prok-RING_1 PF14446.1 AEO58036.1 - 0.0082 15.8 1.3 0.0082 15.8 0.9 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-PHD-like PF15446.1 AEO58036.1 - 0.025 13.8 8.8 0.29 10.4 1.5 2.6 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-HC5HC2H PF13771.1 AEO58036.1 - 0.035 14.2 3.7 0.25 11.5 0.4 2.4 2 0 0 2 2 2 0 PHD-like zinc-binding domain C1_1 PF00130.17 AEO58036.1 - 0.32 10.7 9.8 2.5 7.8 0.6 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.1 AEO58036.1 - 0.51 9.7 12.8 1.3 8.3 2.7 3.1 3 0 0 3 3 3 0 PHD-finger PUF PF00806.14 AEO58037.1 - 3.7e-26 89.0 0.0 0.00018 20.8 0.0 5.8 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.17 AEO58037.1 - 1.2e-13 50.4 0.0 2.5e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO58037.1 - 3.2e-07 30.0 0.0 5.7e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO58037.1 - 1.2e-05 25.2 0.0 2.6e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Zip PF02535.17 AEO58037.1 - 0.0051 15.8 6.1 0.0098 14.9 4.2 1.4 1 0 0 1 1 1 1 ZIP Zinc transporter BAF1_ABF1 PF04684.8 AEO58037.1 - 0.019 13.8 38.3 0.14 10.9 27.2 1.8 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor SelP_N PF04592.9 AEO58037.1 - 1.5 8.1 20.9 4.1 6.7 14.5 1.7 1 0 0 1 1 1 0 Selenoprotein P, N terminal region CDK5_activator PF03261.10 AEO58037.1 - 2.1 7.6 6.5 4.9 6.3 4.5 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Macoilin PF09726.4 AEO58037.1 - 7.9 4.6 10.2 15 3.7 7.1 1.3 1 0 0 1 1 1 0 Transmembrane protein Pkinase PF00069.20 AEO58038.1 - 2.3e-71 239.9 0.0 3.9e-71 239.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO58038.1 - 4.4e-54 183.2 0.0 7e-54 182.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 AEO58038.1 - 8.5e-22 77.3 1.1 2.1e-21 76.1 0.1 2.2 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 AEO58038.1 - 7.6e-07 28.3 0.0 1.3e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PH PF00169.24 AEO58038.1 - 1.6e-05 24.9 0.0 3.1e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 PH domain APH PF01636.18 AEO58038.1 - 0.0031 17.2 4.9 0.0069 16.1 0.1 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family PH_11 PF15413.1 AEO58038.1 - 0.0035 17.5 0.1 0.017 15.4 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain Seadorna_VP7 PF07387.6 AEO58038.1 - 0.017 14.0 0.0 0.029 13.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.17 AEO58038.1 - 0.046 13.0 1.2 0.26 10.5 0.0 2.3 2 0 0 2 2 2 0 RIO1 family tRNA-synt_2b PF00587.20 AEO58039.1 - 4.2e-68 228.3 0.2 6.9e-68 227.6 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 AEO58039.1 - 1.1e-23 82.9 0.7 3.8e-23 81.2 0.0 2.3 3 0 0 3 3 3 1 Anticodon binding domain RRF PF01765.14 AEO58039.1 - 0.057 12.8 0.1 0.057 12.8 0.1 2.1 2 0 0 2 2 2 0 Ribosome recycling factor Brix PF04427.13 AEO58040.1 - 7.3e-38 130.1 0.0 1.1e-37 129.5 0.0 1.3 1 0 0 1 1 1 1 Brix domain BURP PF03181.10 AEO58040.1 - 0.00011 21.4 0.0 0.0002 20.6 0.0 1.3 1 0 0 1 1 1 1 BURP domain Nop14 PF04147.7 AEO58040.1 - 0.75 7.6 18.7 1 7.1 13.0 1.1 1 0 0 1 1 1 0 Nop14-like family TPT PF03151.11 AEO58041.1 - 3.4e-15 55.9 6.7 3.4e-15 55.9 4.7 2.5 2 1 0 2 2 2 2 Triose-phosphate Transporter family Epimerase PF01370.16 AEO58042.1 - 3.9e-56 190.1 0.0 5.9e-56 189.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 AEO58042.1 - 2.8e-23 82.2 0.0 2.9e-22 78.9 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 AEO58042.1 - 1.3e-21 76.6 0.1 6.3e-21 74.4 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 AEO58042.1 - 1.7e-21 76.1 0.0 2.3e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 AEO58042.1 - 1.2e-19 70.3 0.0 1.6e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 AEO58042.1 - 3.8e-08 33.5 0.0 6.7e-08 32.7 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 AEO58042.1 - 0.0012 18.7 0.0 0.16 11.8 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.8 AEO58042.1 - 0.04 13.1 0.0 0.069 12.3 0.0 1.5 1 1 0 1 1 1 0 NmrA-like family Methyltransf_23 PF13489.1 AEO58043.1 - 6.8e-16 58.4 0.0 1.7e-14 53.8 0.0 2.3 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO58043.1 - 2.1e-07 31.3 0.0 8e-07 29.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO58043.1 - 1e-06 29.2 0.2 0.00023 21.6 0.0 3.6 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO58043.1 - 2.3e-06 27.2 0.0 8.9e-06 25.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO58043.1 - 2.6e-06 27.8 0.0 6.9e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 AEO58043.1 - 0.00015 20.9 0.0 0.00042 19.4 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.14 AEO58043.1 - 0.0024 17.8 0.0 0.038 13.9 0.0 2.3 2 0 0 2 2 2 1 FtsJ-like methyltransferase CMAS PF02353.15 AEO58043.1 - 0.039 13.0 0.0 0.059 12.4 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.9 AEO58043.1 - 0.11 11.8 0.0 0.31 10.4 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain Pep3_Vps18 PF05131.9 AEO58044.1 - 8.3e-48 161.5 0.0 2.5e-47 159.9 0.0 1.9 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 AEO58044.1 - 9.8e-12 44.6 4.5 1.1e-06 28.2 0.0 3.7 4 0 0 4 4 4 2 Region in Clathrin and VPS TPR_21 PF09976.4 AEO58044.1 - 0.0042 17.0 1.0 0.012 15.5 0.3 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat zf-RING_2 PF13639.1 AEO58044.1 - 0.0049 16.6 3.0 0.011 15.5 2.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 AEO58044.1 - 0.0087 15.7 3.2 0.018 14.7 2.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain DNA_pol3_theta PF06440.6 AEO58044.1 - 0.034 13.7 0.0 0.092 12.3 0.0 1.7 1 0 0 1 1 1 0 DNA polymerase III, theta subunit DUF2175 PF09943.4 AEO58044.1 - 0.1 12.6 0.1 0.29 11.2 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) zf-rbx1 PF12678.2 AEO58044.1 - 0.15 12.1 0.1 0.43 10.7 0.1 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 AEO58044.1 - 1.7 8.7 3.4 4.8 7.2 1.9 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Asp PF00026.18 AEO58045.1 - 3.2e-65 220.4 0.0 3.9e-65 220.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 AEO58045.1 - 7.3e-13 48.8 0.3 7.7e-12 45.4 0.0 2.6 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 AEO58045.1 - 7.1e-08 32.8 1.9 0.00073 19.9 0.1 3.9 2 2 1 3 3 3 2 Aspartyl protease TAXi_C PF14541.1 AEO58045.1 - 2.7e-05 23.7 0.0 0.00016 21.3 0.0 2.1 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal WD40 PF00400.27 AEO58046.1 - 2.6e-31 106.3 5.8 1.6e-09 37.2 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat Apc4_WD40 PF12894.2 AEO58046.1 - 0.035 13.6 0.0 38 3.8 0.0 3.7 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.1 AEO58046.1 - 0.069 13.4 6.4 1.9 8.8 0.0 4.7 5 0 0 5 5 5 0 PQQ-like domain Nup160 PF11715.3 AEO58046.1 - 0.11 10.5 0.3 1.3 7.1 0.0 2.4 1 1 1 3 3 3 0 Nucleoporin Nup120/160 PUF PF00806.14 AEO58047.1 - 3.2e-58 190.0 5.4 5.9e-08 31.7 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Disulph_isomer PF06491.6 AEO58047.1 - 0.025 14.4 0.1 0.22 11.3 0.0 2.2 2 0 0 2 2 2 0 Disulphide isomerase DUF260 PF03195.9 AEO58047.1 - 0.18 12.1 0.5 74 3.7 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function DUF260 Adeno_GP19K PF04881.8 AEO58048.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Adenovirus GP19K Phosphodiest PF01663.17 AEO58049.1 - 1.7e-15 57.2 0.5 5.4e-15 55.5 0.1 1.9 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 AEO58049.1 - 0.00015 21.0 0.0 0.00038 19.7 0.0 1.7 1 1 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 AEO58049.1 - 0.0016 17.9 1.1 0.0026 17.1 0.8 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily RIC3 PF15361.1 AEO58049.1 - 0.077 13.2 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Meth_synt_2 PF01717.13 AEO58050.1 - 2e-140 467.3 0.0 2.8e-134 447.1 0.0 2.4 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 AEO58050.1 - 7.8e-124 412.9 0.0 7.2e-113 376.9 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.12 AEO58050.1 - 0.022 13.6 0.0 5.7 5.7 0.0 2.4 2 0 0 2 2 2 0 Uroporphyrinogen decarboxylase (URO-D) EF-hand_4 PF12763.2 AEO58051.1 - 2e-27 94.9 0.0 1.2e-15 57.1 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 AEO58051.1 - 4.5e-05 23.4 0.4 0.063 13.4 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 AEO58051.1 - 0.00021 20.3 0.0 0.34 10.3 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 AEO58051.1 - 0.00026 20.5 0.2 1.4 9.0 0.0 3.6 3 0 0 3 3 3 1 EF-hand domain DUF1720 PF08226.6 AEO58051.1 - 0.0023 17.9 23.4 0.0023 17.9 16.2 6.5 4 2 2 6 6 6 2 Domain of unknown function (DUF1720) EF-hand_8 PF13833.1 AEO58051.1 - 0.019 14.5 0.4 2.1 8.0 0.0 3.2 3 0 0 3 3 3 0 EF-hand domain pair Fork_head PF00250.13 AEO58052.1 - 8.5e-35 118.6 0.3 1.8e-34 117.6 0.2 1.4 1 0 0 1 1 1 1 Fork head domain DUF1649 PF07855.7 AEO58053.1 - 1e-65 220.4 0.0 2.4e-65 219.1 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1649) Suf PF05843.9 AEO58053.1 - 0.21 11.3 4.9 0.27 10.9 3.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Peroxin-3 PF04882.7 AEO58054.1 - 6.8e-143 476.4 0.0 7.9e-143 476.2 0.0 1.0 1 0 0 1 1 1 1 Peroxin-3 Sybindin PF04099.7 AEO58055.1 - 2.5e-23 82.3 0.0 3.1e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Pkinase PF00069.20 AEO58056.1 - 1.8e-58 197.7 0.0 4.9e-58 196.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO58056.1 - 7.2e-34 117.0 0.0 1.3e-32 112.9 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO58056.1 - 1e-07 31.2 0.0 2.1e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AEO58056.1 - 8.7e-05 22.3 0.7 0.00087 19.0 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 AEO58057.1 - 1.4e-64 217.7 0.0 2.6e-63 213.5 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO58057.1 - 9.1e-27 93.7 0.0 1.3e-26 93.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 AEO58057.1 - 0.0064 15.5 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 AEO58057.1 - 0.0081 15.1 0.0 0.015 14.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like AAA_10 PF12846.2 AEO58057.1 - 0.065 12.6 0.0 0.093 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain RIO1 PF01163.17 AEO58057.1 - 0.076 12.3 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family RNA_pol_L_2 PF13656.1 AEO58059.1 - 5.5e-30 102.6 0.0 7.9e-30 102.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 AEO58059.1 - 4.6e-11 41.6 0.0 6.1e-11 41.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain SDA1 PF05285.7 AEO58059.1 - 0.42 9.8 4.4 0.48 9.6 3.1 1.1 1 0 0 1 1 1 0 SDA1 Complex1_LYR PF05347.10 AEO58060.1 - 2.8e-07 30.2 0.7 5.8e-07 29.2 0.5 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 AEO58060.1 - 7.1e-06 26.1 0.7 1e-05 25.6 0.5 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 AEO58060.1 - 0.00041 20.7 0.1 0.00051 20.4 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like G10 PF01125.12 AEO58061.1 - 1.7e-61 206.0 3.4 1.9e-61 205.8 2.3 1.0 1 0 0 1 1 1 1 G10 protein zf-C2H2 PF00096.21 AEO58062.1 - 0.013 15.8 9.4 0.047 14.0 0.4 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-met PF12874.2 AEO58062.1 - 0.098 12.8 1.5 12 6.2 0.0 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 AEO58062.1 - 0.12 12.7 11.9 0.42 11.0 0.8 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger DUF629 PF04780.7 AEO58062.1 - 2.8 6.3 4.0 10 4.5 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF629) EST1_DNA_bind PF10373.4 AEO58063.1 - 4e-56 190.2 0.0 6.2e-56 189.6 0.0 1.3 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 AEO58063.1 - 1.2e-24 86.8 1.7 1.3e-24 86.6 0.4 1.7 2 0 0 2 2 2 1 Telomerase activating protein Est1 TPR_11 PF13414.1 AEO58063.1 - 0.0096 15.5 0.1 0.022 14.3 0.0 1.5 1 0 0 1 1 1 1 TPR repeat PfkB PF00294.19 AEO58064.1 - 2.6e-65 220.5 0.0 2.9e-65 220.3 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase B12-binding PF02310.14 AEO58064.1 - 0.12 12.3 0.1 4.5 7.1 0.0 3.2 4 0 0 4 4 4 0 B12 binding domain Ribosomal_L2_C PF03947.13 AEO58065.1 - 7.2e-40 135.8 2.7 1.1e-39 135.1 1.9 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 AEO58065.1 - 5.3e-14 51.9 0.1 1.1e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain WHIM1 PF15612.1 AEO58067.1 - 0.0021 17.8 0.0 0.0061 16.4 0.0 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Nop14 PF04147.7 AEO58067.1 - 0.11 10.4 7.6 0.16 9.8 5.3 1.4 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 AEO58067.1 - 0.8 7.6 4.3 1.3 6.9 3.0 1.3 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.8 AEO58067.1 - 1.3 8.5 15.2 0.12 11.9 5.2 2.5 2 0 0 2 2 2 0 YL1 nuclear protein DUF1770 PF08589.5 AEO58068.1 - 3.5e-28 98.1 3.4 6.2e-28 97.3 2.3 1.4 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF1770) eRF1_2 PF03464.10 AEO58069.1 - 2.5e-46 157.2 0.1 5.1e-46 156.2 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 AEO58069.1 - 5.8e-41 139.3 0.7 1.2e-40 138.2 0.5 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 AEO58069.1 - 1e-28 99.5 0.0 2.2e-28 98.4 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 PDT PF00800.13 AEO58070.1 - 8.9e-57 191.5 0.0 1.2e-56 191.1 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.20 AEO58070.1 - 0.0026 17.2 0.0 0.0057 16.1 0.0 1.7 1 0 0 1 1 1 1 ACT domain LRR_4 PF12799.2 AEO58072.1 - 5.4e-05 22.7 5.4 2.8 7.6 0.0 6.0 5 2 0 5 5 5 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AEO58072.1 - 0.019 14.7 4.1 0.13 12.0 0.1 3.9 3 1 2 5 5 5 0 Leucine rich repeat LRR_6 PF13516.1 AEO58072.1 - 0.1 12.7 8.8 47 4.4 0.0 6.8 8 0 0 8 8 8 0 Leucine Rich repeat Pkinase PF00069.20 AEO58073.1 - 1.1e-69 234.4 0.0 1.9e-69 233.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO58073.1 - 9.1e-51 172.4 0.0 1.5e-50 171.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 AEO58073.1 - 1.3e-30 105.4 0.1 4.5e-30 103.6 0.0 2.0 2 0 0 2 2 2 1 Ras-binding domain of Byr2 SAM_2 PF07647.12 AEO58073.1 - 1.1e-16 60.4 0.2 5.5e-16 58.1 0.0 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 AEO58073.1 - 3.6e-15 55.8 0.0 6.5e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 AEO58073.1 - 5.6e-13 49.1 0.0 1.1e-12 48.3 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kinase-like PF14531.1 AEO58073.1 - 2.9e-08 33.0 0.0 5.4e-05 22.2 0.0 2.3 2 0 0 2 2 2 2 Kinase-like SAM_PNT PF02198.11 AEO58073.1 - 0.029 14.1 0.0 0.051 13.3 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Mucin PF01456.12 AEO58074.1 - 0.052 13.3 21.6 0.082 12.6 15.0 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.7 AEO58074.1 - 3.3 5.3 7.3 4.2 5.0 5.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Herpes_BLLF1 PF05109.8 AEO58074.1 - 9.7 4.0 18.0 12 3.6 12.5 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Pyr_redox_3 PF13738.1 AEO58075.1 - 1e-07 32.2 0.0 0.0058 16.7 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 AEO58075.1 - 1.3e-07 30.8 0.0 0.00085 18.3 0.0 3.3 2 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 AEO58075.1 - 4.8e-05 23.1 0.6 0.087 12.5 0.1 2.9 2 1 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 AEO58075.1 - 0.00037 20.4 0.4 0.1 12.4 0.0 2.8 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AEO58075.1 - 0.003 17.5 0.6 0.025 14.6 0.0 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 AEO58075.1 - 0.01 14.7 0.0 0.018 13.9 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein TrkA_N PF02254.13 AEO58075.1 - 0.011 15.7 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.12 AEO58075.1 - 0.048 12.7 0.0 0.088 11.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 AEO58075.1 - 0.12 10.8 0.0 0.18 10.2 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein ApbA PF02558.11 AEO58075.1 - 0.16 11.3 0.0 0.5 9.8 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Sas10 PF09368.5 AEO58076.1 - 4.3e-30 103.6 8.9 4.3e-30 103.6 6.2 2.6 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 AEO58076.1 - 3.2e-13 49.6 0.0 2.1e-12 47.0 0.0 2.4 3 0 0 3 3 3 1 Sas10/Utp3/C1D family Med3 PF11593.3 AEO58076.1 - 0.03 13.5 0.5 0.069 12.3 0.4 1.5 1 1 0 1 1 1 0 Mediator complex subunit 3 fungal adh_short PF00106.20 AEO58077.1 - 1.3e-19 70.7 2.8 1.5e-19 70.5 0.2 2.5 2 0 0 2 2 2 1 short chain dehydrogenase DUF3716 PF12511.3 AEO58077.1 - 4.5e-16 58.1 8.3 7.7e-16 57.4 5.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) KR PF08659.5 AEO58077.1 - 1.1e-06 28.5 0.7 3.6e-06 26.7 0.1 2.3 2 0 0 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.3 AEO58077.1 - 3.6e-05 23.4 0.1 0.00011 21.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short_C2 PF13561.1 AEO58077.1 - 0.0026 17.5 0.0 0.0045 16.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 AEO58077.1 - 0.0094 15.9 1.9 0.051 13.5 1.1 2.5 2 1 0 2 2 2 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 AEO58077.1 - 0.028 13.5 0.0 0.069 12.2 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.13 AEO58077.1 - 0.054 13.1 0.2 0.17 11.5 0.1 1.9 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PAT1 PF09770.4 AEO58077.1 - 0.36 9.0 29.3 0.53 8.4 20.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ndc1_Nup PF09531.5 AEO58077.1 - 0.64 8.3 3.9 1.1 7.6 2.7 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CDK5_activator PF03261.10 AEO58077.1 - 3.1 7.0 7.3 5.6 6.2 5.1 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein TFIIA PF03153.8 AEO58077.1 - 3.8 7.3 21.1 0.18 11.6 10.9 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit G-alpha PF00503.15 AEO58078.1 - 1.1e-133 445.7 1.0 1.3e-133 445.5 0.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 AEO58078.1 - 2.4e-15 56.2 1.3 2.9e-10 39.6 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.15 AEO58078.1 - 0.00023 20.6 0.0 0.001 18.5 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Miro PF08477.8 AEO58078.1 - 0.0023 18.4 0.1 3.4 8.1 0.0 2.7 2 1 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 AEO58078.1 - 0.0038 16.3 2.8 0.2 10.7 0.0 2.5 2 1 1 3 3 3 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 AEO58078.1 - 0.011 15.1 0.0 0.026 14.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 AEO58078.1 - 0.036 13.5 0.0 1.7 8.0 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MCM PF00493.18 AEO58078.1 - 0.062 12.0 0.0 0.1 11.3 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family FtsK_SpoIIIE PF01580.13 AEO58078.1 - 0.074 12.5 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 AEO58078.1 - 0.12 12.3 0.0 16 5.4 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF1771 PF08590.5 AEO58079.1 - 1.3e-21 76.3 10.2 1.3e-21 76.3 7.1 1.9 3 0 0 3 3 3 1 Domain of unknown function (DUF1771) Smr PF01713.16 AEO58079.1 - 1.6e-16 60.2 0.2 4.9e-16 58.6 0.1 1.9 1 0 0 1 1 1 1 Smr domain PspA_IM30 PF04012.7 AEO58079.1 - 4.7 6.5 9.5 11 5.3 2.8 2.4 1 1 1 2 2 2 0 PspA/IM30 family Med25_SD1 PF11235.3 AEO58080.1 - 0.029 14.6 3.0 0.031 14.6 2.1 1.0 1 0 0 1 1 1 0 Mediator complex subunit 25 synapsin 1 DUF543 PF04418.7 AEO58081.1 - 6.8e-30 102.8 0.0 7.4e-30 102.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) DUF2456 PF10445.4 AEO58081.1 - 0.066 13.1 0.0 0.08 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2456) Urb2 PF10441.4 AEO58082.1 - 5.2e-61 206.0 0.0 1.4e-60 204.6 0.0 1.8 1 0 0 1 1 1 1 Urb2/Npa2 family D123 PF07065.9 AEO58083.1 - 2.7e-75 253.2 0.9 4.3e-73 246.0 0.6 3.6 1 1 0 1 1 1 1 D123 Sigma70_ner PF04546.8 AEO58083.1 - 9.5 5.7 20.0 0.71 9.4 4.3 3.3 3 0 0 3 3 3 0 Sigma-70, non-essential region cwf21 PF08312.7 AEO58084.1 - 7.4e-19 67.3 15.0 7.4e-19 67.3 10.4 1.9 2 0 0 2 2 2 1 cwf21 domain DUF1129 PF06570.6 AEO58084.1 - 0.088 12.1 0.2 0.14 11.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) RasGEF PF00617.14 AEO58085.1 - 7.7e-63 211.6 0.2 1.4e-62 210.7 0.1 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 AEO58085.1 - 1.5e-25 89.2 0.2 3.8e-25 87.9 0.1 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 AEO58085.1 - 4.5e-16 57.9 0.1 9.6e-16 56.9 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 AEO58085.1 - 4.5e-14 51.7 0.2 1e-13 50.6 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 AEO58085.1 - 1.3e-13 50.2 0.1 3.5e-13 48.8 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 AEO58085.1 - 2e-05 24.3 0.0 5e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 WW domain Fungal_trans PF04082.13 AEO58086.1 - 2.5e-15 56.0 1.5 4.2e-15 55.3 1.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 AEO58086.1 - 2.4e-08 33.8 12.5 1.7e-05 24.8 4.1 3.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 AEO58086.1 - 4.7e-05 23.4 13.0 0.0041 17.3 3.6 3.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 AEO58086.1 - 0.00023 21.3 14.7 0.035 14.4 4.0 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type Glyco_hydro_16 PF00722.16 AEO58087.1 - 5.1e-14 51.9 0.0 8.5e-14 51.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 GBV-C_env PF12786.2 AEO58087.1 - 0.025 13.0 0.0 2.1 6.6 0.0 2.1 2 0 0 2 2 2 0 GB virus C genotype envelope HEAT_2 PF13646.1 AEO58088.1 - 7.2e-08 32.6 2.2 0.00017 21.7 0.1 5.0 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.17 AEO58088.1 - 1.7e-06 27.5 1.9 0.36 11.0 0.0 5.2 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 AEO58088.1 - 0.00034 20.9 5.9 0.033 14.6 0.0 5.4 5 0 0 5 5 5 1 HEAT-like repeat mRNA_cap_enzyme PF01331.14 AEO58091.1 - 1.3e-52 178.2 0.2 2e-52 177.6 0.0 1.4 2 0 0 2 2 2 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 AEO58091.1 - 1.2e-22 80.1 0.0 3.9e-22 78.5 0.0 1.9 1 1 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 AEO58091.1 - 1.2e-08 34.5 0.0 1.5e-07 31.0 0.0 2.2 1 1 0 1 1 1 1 ATP dependent DNA ligase domain PX PF00787.19 AEO58092.1 - 2.4e-18 65.9 0.2 1.8e-17 63.1 0.0 2.4 3 0 0 3 3 3 1 PX domain Vps5 PF09325.5 AEO58092.1 - 4.6e-16 58.7 14.6 3e-10 39.7 0.5 2.1 2 0 0 2 2 2 2 Vps5 C terminal like BAR_3_WASP_bdg PF10456.4 AEO58092.1 - 0.0099 15.1 0.3 0.093 11.9 0.5 2.0 2 0 0 2 2 2 1 WASP-binding domain of Sorting nexin protein DUF1675 PF07897.6 AEO58092.1 - 0.14 11.9 2.5 0.29 10.9 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) RNA_polI_A14 PF08203.6 AEO58092.1 - 1.1 9.5 6.8 0.65 10.2 0.6 3.1 2 1 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 PRTP PF01366.13 AEO58092.1 - 2.1 6.2 4.8 0.32 8.9 0.5 1.6 2 0 0 2 2 2 0 Herpesvirus processing and transport protein TPR_11 PF13414.1 AEO58094.1 - 7.9e-29 99.1 37.6 4.1e-06 26.3 0.6 11.9 8 5 6 14 14 14 8 TPR repeat TPR_1 PF00515.23 AEO58094.1 - 8.7e-29 97.9 30.3 0.0004 19.8 0.0 12.9 13 0 0 13 13 13 8 Tetratricopeptide repeat TPR_2 PF07719.12 AEO58094.1 - 3.5e-27 92.0 35.9 0.0019 17.9 0.0 13.5 14 0 0 14 14 13 8 Tetratricopeptide repeat TPR_8 PF13181.1 AEO58094.1 - 4.5e-27 91.7 23.5 0.00011 21.7 0.1 12.6 12 1 0 12 12 12 6 Tetratricopeptide repeat TPR_19 PF14559.1 AEO58094.1 - 2.3e-18 66.2 27.2 3.2e-06 27.3 0.4 10.6 10 2 2 12 12 12 6 Tetratricopeptide repeat TPR_12 PF13424.1 AEO58094.1 - 1.2e-16 60.3 41.4 1.7e-06 27.8 0.1 11.0 8 3 4 12 12 12 4 Tetratricopeptide repeat TPR_7 PF13176.1 AEO58094.1 - 1.7e-16 58.6 23.3 0.00053 19.5 0.0 11.4 12 0 0 12 12 11 4 Tetratricopeptide repeat TPR_16 PF13432.1 AEO58094.1 - 5.9e-13 49.1 49.0 0.00088 19.8 0.0 11.5 7 3 6 13 13 13 5 Tetratricopeptide repeat TPR_17 PF13431.1 AEO58094.1 - 1.2e-10 40.7 10.2 0.18 12.0 0.2 9.9 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_14 PF13428.1 AEO58094.1 - 1.9e-10 40.4 48.6 0.00088 19.7 0.0 13.7 12 5 5 17 17 14 4 Tetratricopeptide repeat TPR_6 PF13174.1 AEO58094.1 - 8.5e-10 38.4 26.0 0.00073 19.8 0.0 10.6 13 0 0 13 13 11 3 Tetratricopeptide repeat Apc3 PF12895.2 AEO58094.1 - 5.7e-07 29.5 9.2 0.025 14.7 0.6 6.4 5 1 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 AEO58094.1 - 0.7 9.9 0.0 0.7 9.9 0.0 7.8 9 0 0 9 9 8 0 Tetratricopeptide repeat DsbD_2 PF13386.1 AEO58095.1 - 0.019 14.6 1.6 0.035 13.8 0.2 1.9 2 0 0 2 2 2 0 Cytochrome C biogenesis protein transmembrane region PrpF PF04303.8 AEO58096.1 - 6.8e-60 202.7 0.2 8.9e-57 192.5 0.1 2.1 1 1 1 2 2 2 2 PrpF protein AAA_2 PF07724.9 AEO58097.1 - 4.5e-47 160.1 0.0 1.1e-45 155.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 AEO58097.1 - 1.5e-27 96.3 0.0 5e-15 55.8 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 AEO58097.1 - 2.5e-22 78.5 1.1 2.5e-22 78.5 0.7 2.5 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 AEO58097.1 - 5.2e-16 58.6 0.1 3.3e-10 39.8 0.0 3.1 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 AEO58097.1 - 3.8e-15 56.3 15.2 3.8e-06 27.0 0.0 6.6 3 2 2 5 5 4 2 AAA ATPase domain AAA_22 PF13401.1 AEO58097.1 - 3.4e-14 53.0 0.2 3.5e-05 23.9 0.0 4.1 3 2 1 4 4 3 2 AAA domain Sigma54_activat PF00158.21 AEO58097.1 - 9.7e-09 34.9 0.0 1.7e-05 24.3 0.0 2.7 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_17 PF13207.1 AEO58097.1 - 4.3e-08 33.9 5.3 0.011 16.5 0.0 3.9 2 2 0 2 2 2 2 AAA domain Clp_N PF02861.15 AEO58097.1 - 4.4e-08 32.9 5.3 0.00021 21.1 0.2 4.1 3 0 0 3 3 3 1 Clp amino terminal domain AAA_18 PF13238.1 AEO58097.1 - 6.9e-08 32.8 0.0 0.0047 17.2 0.0 3.4 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 AEO58097.1 - 1.6e-07 30.9 0.6 0.025 14.3 0.0 3.6 3 0 0 3 3 3 2 Part of AAA domain IstB_IS21 PF01695.12 AEO58097.1 - 3.2e-07 29.9 0.0 0.025 13.9 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein Arch_ATPase PF01637.13 AEO58097.1 - 7.6e-07 29.0 5.2 0.0096 15.6 0.1 5.0 5 1 1 6 6 6 1 Archaeal ATPase Mg_chelatase PF01078.16 AEO58097.1 - 6.5e-06 25.4 0.1 0.13 11.4 0.0 3.5 2 1 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 AEO58097.1 - 2.4e-05 24.3 1.1 0.26 11.2 0.0 3.6 4 0 0 4 4 3 2 AAA domain AAA_33 PF13671.1 AEO58097.1 - 3.4e-05 23.7 0.0 0.21 11.4 0.0 3.2 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 AEO58097.1 - 5.9e-05 23.2 0.0 0.46 10.6 0.0 2.6 2 0 0 2 2 2 2 RNA helicase T2SE PF00437.15 AEO58097.1 - 8.9e-05 21.5 0.1 0.013 14.4 0.0 2.8 2 1 0 2 2 2 1 Type II/IV secretion system protein AAA_3 PF07726.6 AEO58097.1 - 0.00012 21.7 0.0 0.75 9.3 0.0 3.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 AEO58097.1 - 0.00012 21.5 1.8 1.3 8.3 0.0 4.2 3 1 1 4 4 4 2 AAA domain MobB PF03205.9 AEO58097.1 - 0.00017 21.2 0.0 0.85 9.3 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B ResIII PF04851.10 AEO58097.1 - 0.00031 20.6 0.0 0.18 11.6 0.0 3.5 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit ABC_tran PF00005.22 AEO58097.1 - 0.00054 20.2 0.5 0.84 9.9 0.0 3.3 3 0 0 3 3 3 1 ABC transporter DUF258 PF03193.11 AEO58097.1 - 0.00081 18.6 0.0 0.45 9.7 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_24 PF13479.1 AEO58097.1 - 0.00083 18.9 0.0 0.78 9.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 AEO58097.1 - 0.00095 18.6 0.0 0.82 9.2 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain NTPase_1 PF03266.10 AEO58097.1 - 0.0016 18.1 0.0 0.27 10.9 0.0 3.5 3 0 0 3 3 3 1 NTPase Torsin PF06309.6 AEO58097.1 - 0.0018 18.1 0.0 0.0095 15.8 0.0 2.0 2 0 0 2 2 2 1 Torsin AAA_10 PF12846.2 AEO58097.1 - 0.0025 17.2 6.2 0.19 11.1 0.1 5.1 5 1 0 5 5 5 1 AAA-like domain NACHT PF05729.7 AEO58097.1 - 0.0037 16.9 0.0 0.35 10.4 0.0 2.7 2 0 0 2 2 2 1 NACHT domain SRP54 PF00448.17 AEO58097.1 - 0.021 14.2 0.0 3.8 6.9 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_21 PF13304.1 AEO58097.1 - 0.026 14.4 0.0 2.3 8.1 0.0 2.9 3 0 0 3 3 2 0 AAA domain UPF0079 PF02367.12 AEO58097.1 - 0.033 13.8 0.0 8.7 6.0 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 MMR_HSR1 PF01926.18 AEO58097.1 - 0.045 13.7 0.7 1.4 8.9 0.0 3.5 3 2 0 3 3 3 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 AEO58097.1 - 0.083 12.4 0.0 10 5.5 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 AEO58097.1 - 0.094 12.1 0.0 7 6.1 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Peptidase_M16 PF00675.15 AEO58097.1 - 0.13 12.0 2.3 3.4 7.4 0.0 2.7 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) IncA PF04156.9 AEO58097.1 - 0.45 10.0 7.1 1.6 8.3 4.9 2.0 1 0 0 1 1 1 0 IncA protein DUF724 PF05266.9 AEO58097.1 - 0.48 10.0 5.7 0.37 10.4 2.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF724) V_ATPase_I PF01496.14 AEO58097.1 - 0.93 7.2 3.0 1.6 6.4 2.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1266 PF06889.6 AEO58097.1 - 1.4 8.6 4.9 3.4 7.4 3.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) Macoilin PF09726.4 AEO58097.1 - 3.2 5.9 9.9 6.1 5.0 6.8 1.3 1 0 0 1 1 1 0 Transmembrane protein Mhr1 PF12829.2 AEO58098.1 - 4.4e-26 90.5 0.0 7.2e-26 89.8 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination Ribosomal_60s PF00428.14 AEO58098.1 - 4.8 7.6 37.2 1.2 9.6 5.4 3.3 3 0 0 3 3 3 0 60s Acidic ribosomal protein Sulfotransfer_3 PF13469.1 AEO58099.1 - 0.0002 22.2 0.0 0.00047 21.1 0.0 1.6 1 1 0 1 1 1 1 Sulfotransferase family PIG-X PF08320.7 AEO58100.1 - 1.3e-62 210.8 0.0 1.7e-62 210.4 0.0 1.2 1 0 0 1 1 1 1 PIG-X / PBN1 Rhodanese PF00581.15 AEO58101.1 - 1.9e-08 34.6 0.0 6.5e-08 32.9 0.0 1.9 1 0 0 1 1 1 1 Rhodanese-like domain Peptidase_C14 PF00656.17 AEO58101.1 - 0.0064 16.2 0.0 0.079 12.6 0.0 2.0 1 1 1 2 2 2 1 Caspase domain DUF4372 PF14294.1 AEO58101.1 - 0.022 14.6 0.1 0.052 13.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4372) Homeobox_KN PF05920.6 AEO58102.1 - 0.00038 20.1 0.1 0.00093 18.8 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 AEO58102.1 - 0.012 15.2 0.1 0.03 13.9 0.0 1.6 1 0 0 1 1 1 0 Homeobox domain HAUS6_N PF14661.1 AEO58102.1 - 0.22 10.8 1.7 0.32 10.2 1.2 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus 2OG-FeII_Oxy PF03171.15 AEO58103.1 - 0.00029 21.0 0.0 0.0011 19.1 0.0 2.0 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 AEO58103.1 - 0.091 13.2 0.9 1.7 9.2 0.6 2.5 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.13 AEO58104.1 - 2.7e-11 42.8 0.0 5.7e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain NAD_binding_1 PF00175.16 AEO58105.1 - 1.7e-28 99.3 0.0 2.6e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 AEO58105.1 - 1.3e-27 95.8 0.0 2e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 AEO58105.1 - 0.00016 21.5 0.0 0.019 14.8 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 AEO58105.1 - 0.018 14.9 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain DUF3605 PF12239.3 AEO58106.1 - 4.2e-57 192.4 0.0 5.3e-57 192.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) DUF788 PF05620.6 AEO58107.1 - 7e-46 156.1 0.0 7.7e-46 156.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) DUF2955 PF11168.3 AEO58107.1 - 0.0011 18.6 0.4 0.51 10.0 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2955) UbiA PF01040.13 AEO58107.1 - 0.0072 15.5 7.8 0.0091 15.2 5.4 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family 7TMR-DISM_7TM PF07695.6 AEO58107.1 - 0.012 15.2 0.1 0.012 15.2 0.1 1.9 2 0 0 2 2 2 0 7TM diverse intracellular signalling DUF1467 PF07330.7 AEO58107.1 - 0.11 12.2 3.6 0.11 12.3 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1467) FA_desaturase PF00487.19 AEO58107.1 - 5.6 6.3 9.7 14 5.0 6.8 1.5 1 1 1 2 2 2 0 Fatty acid desaturase TPR_11 PF13414.1 AEO58108.1 - 4e-44 148.1 20.3 1.1e-14 53.7 2.7 7.4 5 3 2 7 7 7 7 TPR repeat TPR_2 PF07719.12 AEO58108.1 - 2e-37 124.0 19.4 1.2e-06 28.0 0.4 10.4 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_1 PF00515.23 AEO58108.1 - 5.3e-37 123.9 19.4 7.3e-08 31.7 0.7 9.7 10 0 0 10 10 9 7 Tetratricopeptide repeat Apc3 PF12895.2 AEO58108.1 - 3.5e-32 110.3 13.3 1.9e-20 72.8 0.0 4.4 4 0 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 AEO58108.1 - 9.5e-27 92.7 18.8 2.5e-10 40.1 0.1 7.8 4 2 3 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.1 AEO58108.1 - 2.7e-25 86.2 0.5 4.6e-06 26.0 0.3 9.4 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_14 PF13428.1 AEO58108.1 - 5.3e-24 82.5 16.3 0.0031 18.0 0.2 10.6 5 1 5 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.1 AEO58108.1 - 3.9e-23 81.5 12.0 2.7e-08 34.0 0.9 6.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 AEO58108.1 - 3e-22 78.6 32.1 5.3e-08 33.3 0.9 8.3 6 2 2 8 8 8 4 Tetratricopeptide repeat TPR_7 PF13176.1 AEO58108.1 - 5.3e-20 69.5 5.8 0.00021 20.8 0.0 7.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 AEO58108.1 - 5.7e-20 69.8 7.9 0.00035 20.5 0.3 9.0 10 0 0 10 10 8 5 Tetratricopeptide repeat TPR_6 PF13174.1 AEO58108.1 - 1.8e-14 53.0 8.1 0.012 15.9 0.0 9.1 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_15 PF13429.1 AEO58108.1 - 6.1e-06 25.5 8.2 0.0056 15.7 0.1 4.3 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 AEO58108.1 - 4.4e-05 23.2 18.3 0.006 16.4 0.3 5.3 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_4 PF07721.9 AEO58108.1 - 0.00015 21.8 0.5 17 6.2 0.2 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 AEO58108.1 - 0.00069 19.4 6.6 7.4 6.5 0.1 4.7 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat DUF2225 PF09986.4 AEO58108.1 - 0.0018 17.7 0.2 2.5 7.5 0.1 3.2 3 0 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_10 PF13374.1 AEO58108.1 - 0.01 15.7 12.7 1.7 8.6 0.0 5.4 4 1 1 5 5 5 0 Tetratricopeptide repeat Foie-gras_1 PF11817.3 AEO58108.1 - 0.045 13.2 2.2 0.52 9.7 0.1 2.9 3 1 0 3 3 3 0 Foie gras liver health family 1 NARP1 PF12569.3 AEO58108.1 - 0.25 10.0 3.6 16 4.1 0.9 3.4 2 1 0 4 4 4 0 NMDA receptor-regulated protein 1 APP_E2 PF12925.2 AEO58108.1 - 0.28 10.7 4.2 4 6.9 0.0 2.8 1 1 0 2 2 2 0 E2 domain of amyloid precursor protein MIT PF04212.13 AEO58108.1 - 0.38 10.6 6.3 24 4.8 0.1 4.3 4 1 0 4 4 3 0 MIT (microtubule interacting and transport) domain Histone PF00125.19 AEO58109.1 - 1.8e-15 56.7 0.1 2.2e-15 56.5 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 AEO58109.1 - 0.00012 21.9 0.1 0.00017 21.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 AEO58109.1 - 0.00012 22.1 0.1 0.00017 21.7 0.0 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 AEO58109.1 - 0.00033 20.6 0.1 0.00059 19.8 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 AEO58109.1 - 0.013 15.2 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 AEO58109.1 - 0.022 14.0 0.0 0.022 14.0 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Sedlin_N PF04628.8 AEO58110.1 - 4.4e-45 152.7 0.0 5e-45 152.5 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 AEO58110.1 - 4.5e-05 23.1 0.7 0.0013 18.4 0.1 2.1 1 1 0 2 2 2 1 Sybindin-like family NLBH PF05211.7 AEO58110.1 - 0.13 11.5 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Neuraminyllactose-binding hemagglutinin precursor (NLBH) L31 PF09784.4 AEO58111.1 - 1.9e-48 162.7 2.3 2.1e-48 162.6 1.6 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 DUF2951 PF11166.3 AEO58111.1 - 0.12 12.2 0.2 0.15 11.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) RRM_1 PF00076.17 AEO58112.1 - 5e-16 58.0 0.0 7.2e-16 57.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO58112.1 - 2.7e-12 46.4 0.0 3.9e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO58112.1 - 7.7e-09 35.2 0.1 1.2e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup88 PF10168.4 AEO58113.1 - 0.0085 13.9 8.1 0.19 9.5 0.0 3.3 3 1 0 3 3 3 1 Nuclear pore component Herpes_U30 PF04523.8 AEO58113.1 - 0.02 12.3 1.1 0.028 11.9 0.8 1.1 1 0 0 1 1 1 0 Herpes virus tegument protein U30 TPR_MLP1_2 PF07926.7 AEO58113.1 - 0.058 13.1 6.7 0.14 11.9 4.7 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF1090 PF06476.7 AEO58113.1 - 0.18 11.4 7.0 0.32 10.6 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) Snapin_Pallidin PF14712.1 AEO58113.1 - 0.19 12.0 6.8 2.5 8.4 4.4 2.5 1 1 0 1 1 1 0 Snapin/Pallidin AATF-Che1 PF13339.1 AEO58113.1 - 0.38 10.8 7.2 0.71 10.0 3.8 2.0 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Laminin_II PF06009.7 AEO58113.1 - 0.45 10.2 6.1 0.93 9.2 4.2 1.4 1 0 0 1 1 1 0 Laminin Domain II CENP-F_leu_zip PF10473.4 AEO58113.1 - 0.6 9.9 12.7 0.8 9.5 0.7 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Atg14 PF10186.4 AEO58113.1 - 2.8 6.8 7.7 4.7 6.0 5.3 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 V_ATPase_I PF01496.14 AEO58113.1 - 5.9 4.6 4.3 8.2 4.1 3.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family C-C_Bond_Lyase PF15617.1 AEO58114.1 - 0.24 10.1 0.0 0.36 9.5 0.0 1.1 1 0 0 1 1 1 0 C-C_Bond_Lyase of the TIM-Barrel fold Nop14 PF04147.7 AEO58114.1 - 0.46 8.3 6.1 0.63 7.8 4.3 1.1 1 0 0 1 1 1 0 Nop14-like family PAT1 PF09770.4 AEO58114.1 - 6.2 4.9 18.7 9.5 4.3 13.0 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PI3_PI4_kinase PF00454.22 AEO58115.1 - 1.6e-30 106.2 0.0 2.9e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.3 AEO58115.1 - 7.6e-20 70.3 0.0 1.7e-19 69.2 0.0 1.7 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 TFIIF_alpha PF05793.7 AEO58115.1 - 8.3 4.6 8.4 13 4.0 5.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) AA_permease_2 PF13520.1 AEO58116.1 - 5.9e-79 265.5 32.0 7.3e-79 265.2 22.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 AEO58116.1 - 3.6e-14 51.9 27.0 4.9e-14 51.5 18.7 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3392 PF11872.3 AEO58116.1 - 0.62 10.0 6.7 0.98 9.4 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3392) MliC PF09864.4 AEO58117.1 - 0.085 12.6 0.5 1.2 8.9 0.0 2.7 3 0 0 3 3 3 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme CBFD_NFYB_HMF PF00808.18 AEO58118.1 - 1.1e-12 47.7 1.5 1.8e-12 47.1 1.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 AEO58118.1 - 6.3e-05 23.0 0.4 0.00011 22.2 0.3 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 FGGY_C PF02782.11 AEO58120.1 - 2.5e-26 92.5 0.0 1.1e-25 90.4 0.0 2.0 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 AEO58120.1 - 5.2e-23 81.6 0.0 1.1e-13 51.0 0.0 2.5 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Sad1_UNC PF07738.8 AEO58121.1 - 3.8e-37 127.1 0.0 6.1e-37 126.4 0.0 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Muskelin_N PF06588.6 AEO58121.1 - 0.0033 17.1 0.0 0.0061 16.2 0.0 1.4 1 0 0 1 1 1 1 Muskelin N-terminus RRM_2 PF04059.7 AEO58122.1 - 2.7e-14 52.9 0.1 5.2e-14 52.0 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif 2 Pkinase PF00069.20 AEO58123.1 - 2.3e-31 108.8 0.0 5.2e-31 107.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO58123.1 - 1.1e-07 31.2 0.1 0.0037 16.3 0.0 3.2 4 0 0 4 4 4 2 Protein tyrosine kinase Sec15 PF04091.7 AEO58124.1 - 2e-104 349.3 1.9 2e-104 349.3 1.3 2.0 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like DUF4201 PF13870.1 AEO58124.1 - 0.0066 15.8 4.2 0.0066 15.8 2.9 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) DUF3510 PF12022.3 AEO58124.1 - 0.007 16.4 1.9 3.6 7.7 0.0 3.6 3 0 0 3 3 3 2 Domain of unknown function (DUF3510) COG5 PF10392.4 AEO58124.1 - 0.029 14.3 9.0 0.035 14.0 3.1 3.0 3 0 0 3 3 3 0 Golgi transport complex subunit 5 Skp1 PF01466.14 AEO58124.1 - 0.083 12.9 2.2 15 5.7 0.0 3.2 3 0 0 3 3 3 0 Skp1 family, dimerisation domain DUF2450 PF10475.4 AEO58124.1 - 0.24 10.2 9.2 0.041 12.7 3.6 1.7 2 0 0 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) Rbsn PF11464.3 AEO58124.1 - 0.78 9.3 6.4 0.19 11.3 0.3 2.8 3 0 0 3 3 3 0 Rabenosyn Rab binding domain CBFD_NFYB_HMF PF00808.18 AEO58125.1 - 1.2e-19 70.1 0.6 2e-19 69.4 0.4 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 AEO58125.1 - 2.8e-11 43.3 1.4 2.9e-11 43.3 0.1 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 AEO58125.1 - 0.021 14.6 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X tRNA-synt_1b PF00579.20 AEO58126.1 - 1.2e-60 205.1 0.0 5.6e-32 111.0 0.0 2.3 1 1 1 2 2 2 2 tRNA synthetases class I (W and Y) Fcf2 PF08698.6 AEO58126.1 - 1.4e-25 89.1 0.0 4.1e-25 87.6 0.0 1.8 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing Ribosomal_S10 PF00338.17 AEO58126.1 - 2.2e-22 78.7 0.0 5.7e-22 77.3 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e Pex14_N PF04695.8 AEO58126.1 - 0.051 13.6 0.3 15 5.6 0.0 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3918 PF13056.1 AEO58126.1 - 0.7 9.2 3.1 7.1 6.0 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3918) Xpo1 PF08389.7 AEO58127.1 - 0.0003 20.7 0.0 0.0055 16.6 0.0 2.8 2 1 0 2 2 2 1 Exportin 1-like protein Peptidase_M24 PF00557.19 AEO58128.1 - 6.2e-44 150.0 0.0 1e-43 149.3 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 AEO58128.1 - 5.4e-27 94.8 0.2 5.9e-22 78.5 0.0 2.6 3 0 0 3 3 3 2 Creatinase/Prolidase N-terminal domain Foamy_virus_ENV PF03408.9 AEO58128.1 - 0.11 10.0 0.0 0.15 9.5 0.0 1.1 1 0 0 1 1 1 0 Foamy virus envelope protein FUN14 PF04930.10 AEO58129.1 - 2.2e-05 24.6 9.2 3.6e-05 23.9 3.4 2.7 2 1 0 2 2 2 1 FUN14 family DUF543 PF04418.7 AEO58129.1 - 0.019 14.8 2.1 2.9 7.9 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF543) TauE PF01925.14 AEO58129.1 - 0.034 13.6 6.0 0.063 12.7 4.2 1.5 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE Pkinase_Tyr PF07714.12 AEO58130.1 - 5.5e-14 51.8 0.0 1.4e-08 34.1 0.0 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 AEO58130.1 - 1.1e-12 47.6 0.0 1.1e-08 34.5 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain RIO1 PF01163.17 AEO58130.1 - 0.00099 18.4 0.1 0.0018 17.6 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Phage_AlpA PF05930.7 AEO58130.1 - 0.039 13.6 0.1 0.44 10.3 0.1 2.2 1 1 0 1 1 1 0 Prophage CP4-57 regulatory protein (AlpA) Rgp1 PF08737.5 AEO58131.1 - 2.5 7.0 5.0 4 6.4 2.9 1.7 1 1 1 2 2 2 0 Rgp1 TIP41 PF04176.8 AEO58132.1 - 8.8e-69 230.3 0.0 1.1e-68 230.1 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family Pkinase PF00069.20 AEO58133.1 - 2.7e-71 239.7 0.0 3.6e-71 239.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO58133.1 - 2.5e-44 151.2 0.0 3.4e-44 150.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO58133.1 - 2.4e-07 29.9 0.0 1.3e-06 27.6 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 AEO58133.1 - 0.00036 19.6 0.1 0.00065 18.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AEO58133.1 - 0.0082 15.9 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 AEO58133.1 - 0.017 14.4 0.1 0.036 13.4 0.0 1.6 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.17 AEO58133.1 - 0.02 14.2 0.0 0.081 12.2 0.0 1.8 1 1 1 2 2 2 0 RIO1 family DUF1180 PF06679.7 AEO58133.1 - 1.2 8.9 5.4 1.7 8.4 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Peptidase_M76 PF09768.4 AEO58134.1 - 4.3e-65 218.3 0.3 6.2e-65 217.8 0.2 1.2 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.4 AEO58134.1 - 0.0024 17.5 1.8 0.0059 16.2 1.3 1.7 1 1 0 1 1 1 1 SprT-like family DUF2360 PF10152.4 AEO58134.1 - 0.016 15.5 3.6 0.023 15.0 2.5 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Peptidase_MA_2 PF13485.1 AEO58134.1 - 0.044 13.8 0.1 0.082 12.9 0.1 1.5 1 0 0 1 1 1 0 Peptidase MA superfamily Suf PF05843.9 AEO58134.1 - 0.94 9.1 5.3 1.4 8.6 3.7 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SR-25 PF10500.4 AEO58134.1 - 1 8.8 9.9 1.5 8.2 6.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pex14_N PF04695.8 AEO58134.1 - 1.5 8.8 8.7 2.4 8.1 6.0 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3446 PF11928.3 AEO58134.1 - 7.1 6.9 12.6 12 6.1 8.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) AA_kinase PF00696.23 AEO58135.1 - 1.4e-40 139.3 1.0 1.4e-40 139.3 0.7 1.6 2 0 0 2 2 2 1 Amino acid kinase family PUA PF01472.15 AEO58135.1 - 9.3e-17 60.5 1.1 5.1e-09 35.7 0.0 3.2 3 0 0 3 3 3 2 PUA domain CDC45 PF02724.9 AEO58135.1 - 0.035 12.1 0.6 0.046 11.7 0.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Ribosomal_60s PF00428.14 AEO58135.1 - 0.042 14.2 16.2 0.031 14.6 2.2 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein UPF0113 PF03657.8 AEO58136.1 - 2.1e-07 30.7 0.0 3.1e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) GMC_oxred_N PF00732.14 AEO58137.1 - 2.4e-25 89.2 0.0 7.2e-25 87.7 0.0 1.9 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 AEO58137.1 - 5e-23 81.9 0.1 8.4e-23 81.2 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase CBM_1 PF00734.13 AEO58137.1 - 3.6e-12 45.7 8.2 1.1e-11 44.2 5.7 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain FAD_binding_2 PF00890.19 AEO58137.1 - 7.4e-11 41.5 0.7 1.1e-05 24.4 0.3 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 AEO58137.1 - 9.5e-06 24.7 0.7 0.00041 19.3 0.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 AEO58137.1 - 1.2e-05 24.6 0.1 0.0025 16.9 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 AEO58137.1 - 0.00051 18.6 0.3 0.00078 18.0 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.1 AEO58137.1 - 0.00066 19.6 0.7 0.0023 17.9 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 AEO58137.1 - 0.00073 19.4 0.0 0.0028 17.5 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DOMON PF03351.12 AEO58137.1 - 0.00092 19.1 0.0 0.0026 17.6 0.0 1.7 1 0 0 1 1 1 1 DOMON domain Pyr_redox_3 PF13738.1 AEO58137.1 - 0.0016 18.5 0.1 0.036 14.1 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 AEO58137.1 - 0.014 14.2 0.6 0.028 13.2 0.1 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.14 AEO58137.1 - 0.017 14.1 0.2 0.026 13.5 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 AEO58137.1 - 0.026 13.6 0.1 0.052 12.6 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 AEO58137.1 - 0.028 14.8 0.3 0.54 10.7 0.2 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Acetyltransf_1 PF00583.19 AEO58138.1 - 3e-06 27.1 0.0 1.6e-05 24.7 0.0 2.2 3 0 0 3 3 3 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 AEO58138.1 - 0.0019 18.3 0.0 0.0035 17.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 AEO58138.1 - 0.012 15.8 0.0 0.035 14.2 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Arf PF00025.16 AEO58139.1 - 1.4e-55 187.2 0.2 1.6e-55 187.0 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 AEO58139.1 - 2.3e-12 46.3 1.4 2.6e-07 29.6 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 AEO58139.1 - 5.5e-10 39.7 0.0 7e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 AEO58139.1 - 6.8e-10 38.4 0.0 8e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 AEO58139.1 - 8.2e-10 38.3 0.0 9.7e-10 38.0 0.0 1.0 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 AEO58139.1 - 3.4e-09 36.6 0.0 4.3e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 AEO58139.1 - 1.2e-07 31.0 0.0 1.5e-07 30.8 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 AEO58139.1 - 4.4e-05 22.9 0.0 0.0046 16.4 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain NACHT PF05729.7 AEO58139.1 - 0.013 15.1 0.1 0.21 11.2 0.0 2.0 2 0 0 2 2 2 0 NACHT domain Dynamin_N PF00350.18 AEO58139.1 - 0.021 14.6 0.0 0.33 10.7 0.0 2.0 2 0 0 2 2 2 0 Dynamin family FeoB_N PF02421.13 AEO58139.1 - 0.021 14.0 0.3 0.058 12.6 0.2 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_17 PF13207.1 AEO58139.1 - 0.046 14.5 0.0 0.06 14.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 AEO58139.1 - 0.047 13.1 0.1 0.09 12.2 0.1 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation 6PF2K PF01591.13 AEO58139.1 - 0.078 12.0 0.2 0.21 10.6 0.1 1.6 1 1 0 2 2 2 0 6-phosphofructo-2-kinase DUF4045 PF13254.1 AEO58140.1 - 8.3e-76 255.9 34.3 1.4e-47 162.9 17.6 6.1 4 3 2 7 7 7 2 Domain of unknown function (DUF4045) Gelsolin PF00626.17 AEO58140.1 - 1.3e-08 34.3 0.0 0.014 15.0 0.0 3.5 3 0 0 3 3 3 2 Gelsolin repeat Med10 PF09748.4 AEO58141.1 - 1.3e-46 157.5 0.1 1.6e-46 157.2 0.1 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF2408 PF10303.4 AEO58141.1 - 0.15 12.2 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) bZIP_1 PF00170.16 AEO58143.1 - 2.8e-05 24.0 8.4 5.1e-05 23.1 5.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor GvpL_GvpF PF06386.6 AEO58143.1 - 0.32 10.5 3.6 0.49 9.9 2.5 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF bZIP_2 PF07716.10 AEO58143.1 - 0.67 9.8 8.5 1.5 8.6 5.9 1.6 1 0 0 1 1 1 0 Basic region leucine zipper DUF4407 PF14362.1 AEO58143.1 - 1.2 7.9 4.8 1.8 7.4 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Stm1_N PF09598.5 AEO58144.1 - 2.9e-15 56.6 0.2 2.9e-15 56.6 0.1 4.0 3 2 1 4 4 4 1 Stm1 HABP4_PAI-RBP1 PF04774.10 AEO58144.1 - 9.9e-07 29.2 12.4 9.9e-07 29.2 8.6 2.2 2 1 1 3 3 3 1 Hyaluronan / mRNA binding family MFS_1 PF07690.11 AEO58145.1 - 6.1e-17 61.3 40.6 8.2e-09 34.6 6.8 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 AEO58145.1 - 1.3e-07 30.3 16.7 1.4e-05 23.7 3.1 3.2 3 1 0 3 3 3 3 MFS/sugar transport protein Sugar_tr PF00083.19 AEO58145.1 - 0.0015 17.2 11.9 0.29 9.6 3.0 3.3 3 0 0 3 3 3 2 Sugar (and other) transporter LacY_symp PF01306.14 AEO58145.1 - 0.51 8.8 10.6 0.038 12.5 1.5 2.6 3 0 0 3 3 3 0 LacY proton/sugar symporter Mtc PF03820.12 AEO58146.1 - 3.3e-104 347.8 0.1 2.2e-101 338.5 0.1 2.0 1 1 0 1 1 1 1 Tricarboxylate carrier Pkinase PF00069.20 AEO58147.1 - 2.7e-59 200.4 0.0 4.3e-59 199.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO58147.1 - 3.7e-19 68.8 0.0 1.6e-18 66.7 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 AEO58147.1 - 0.028 13.7 0.1 0.1 11.9 0.0 1.9 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.1 AEO58147.1 - 0.036 13.0 0.6 1.9 7.3 0.0 2.3 2 0 0 2 2 2 0 Kinase-like BAF1_ABF1 PF04684.8 AEO58147.1 - 0.56 8.9 20.7 1.2 7.8 14.3 1.5 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor zf-RING_4 PF14570.1 AEO58148.1 - 0.12 11.9 0.3 0.18 11.3 0.2 1.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Lactamase_B_2 PF12706.2 AEO58149.1 - 1.4e-31 109.5 0.0 2.2e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 AEO58149.1 - 1.5e-26 91.6 0.0 3.5e-26 90.4 0.0 1.7 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.22 AEO58149.1 - 3.4e-08 33.3 0.5 8.4e-08 32.0 0.3 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily DEAD PF00270.24 AEO58150.1 - 4.8e-44 149.8 0.1 9.4e-44 148.8 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2183 PF09949.4 AEO58150.1 - 7.5e-32 109.2 0.0 2.2e-31 107.7 0.0 1.9 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Helicase_C PF00271.26 AEO58150.1 - 1.7e-18 66.2 0.0 3.8e-18 65.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain LNS2 PF08235.8 AEO58150.1 - 0.0023 17.5 0.0 0.0048 16.4 0.0 1.5 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) DUF1253 PF06862.7 AEO58150.1 - 0.013 13.9 0.3 1.4 7.2 0.0 3.2 2 1 2 4 4 4 0 Protein of unknown function (DUF1253) RVT_1 PF00078.22 AEO58151.1 - 0.00061 19.2 0.0 0.00063 19.1 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MarR_2 PF12802.2 AEO58153.1 - 0.02 14.5 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 MarR family HTH_29 PF13551.1 AEO58153.1 - 0.067 13.3 0.0 0.067 13.3 0.0 1.1 1 0 0 1 1 1 0 Winged helix-turn helix Glyco_hydro_16 PF00722.16 AEO58155.1 - 1.8e-07 30.6 0.0 3.1e-07 29.8 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Flavin_Reduct PF01613.13 AEO58156.1 - 1.5e-17 63.8 0.0 2.3e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain PDEase_II PF02112.10 AEO58157.1 - 5.7e-53 179.9 0.0 1.2e-22 80.2 0.0 3.4 3 1 0 3 3 3 3 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 AEO58157.1 - 0.00099 18.6 0.0 0.0026 17.3 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 AEO58157.1 - 0.03 13.9 1.7 0.14 11.7 1.2 2.2 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily TFIIF_alpha PF05793.7 AEO58158.1 - 1.3 7.3 8.4 1.9 6.7 5.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) AMP-binding PF00501.23 AEO58159.1 - 2.9e-60 203.8 0.9 1.1e-21 76.7 0.0 4.9 4 1 0 4 4 4 4 AMP-binding enzyme DMAP_binding PF06464.6 AEO58159.1 - 3.5e-12 46.9 0.3 3.5e-12 46.9 0.2 2.4 2 0 0 2 2 2 1 DMAP1-binding Domain GvpG PF05120.7 AEO58159.1 - 0.0025 17.5 0.9 0.0065 16.2 0.6 1.6 1 0 0 1 1 1 1 Gas vesicle protein G HET PF06985.6 AEO58160.1 - 1.1e-05 25.6 0.0 4.1e-05 23.7 0.0 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PX PF00787.19 AEO58162.1 - 3.3e-15 55.8 0.0 5e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 PX domain SNARE PF05739.14 AEO58162.1 - 4.4e-07 29.5 0.9 7.2e-07 28.7 0.6 1.4 1 0 0 1 1 1 1 SNARE domain DUF1996 PF09362.5 AEO58163.1 - 5.5e-81 271.6 0.9 6.6e-81 271.4 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) EB1 PF03271.12 AEO58164.1 - 4e-17 61.9 1.2 9.4e-17 60.7 0.8 1.7 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 AEO58164.1 - 1.3e-06 28.4 1.3 2.3e-06 27.5 0.9 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain Syja_N PF02383.13 AEO58164.1 - 0.085 11.6 0.0 0.092 11.4 0.0 1.1 1 0 0 1 1 1 0 SacI homology domain DUF4350 PF14258.1 AEO58165.1 - 0.027 14.6 0.0 0.046 13.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4350) NAD_binding_8 PF13450.1 AEO58167.1 - 0.0063 16.5 0.0 0.0073 16.3 0.0 1.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Flavokinase PF01687.12 AEO58168.1 - 4.8e-08 32.9 0.0 1.2e-07 31.6 0.0 1.6 2 0 0 2 2 2 1 Riboflavin kinase Glyco_hydro_61 PF03443.9 AEO58169.1 - 2.1e-62 210.7 0.0 4e-62 209.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 AEO58169.1 - 1.1e-09 37.7 14.2 1.1e-09 37.7 9.8 3.4 2 1 1 3 3 3 1 Fungal cellulose binding domain NPCBM_assoc PF10633.4 AEO58169.1 - 0.018 15.1 0.3 1.2 9.2 0.0 3.4 4 0 0 4 4 4 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Man-6-P_recep PF02157.10 AEO58171.1 - 2.9e-11 42.9 0.0 3.9e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.5 AEO58171.1 - 1.1e-06 28.1 0.3 1.1e-06 28.1 0.2 3.2 2 1 1 3 3 3 1 Autophagy-related protein 27 CIMR PF00878.13 AEO58171.1 - 1.9e-05 24.4 0.2 0.0027 17.4 0.1 2.3 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Daxx PF03344.10 AEO58171.1 - 0.41 9.0 6.0 0.54 8.6 4.2 1.1 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 AEO58171.1 - 0.67 7.9 8.8 0.85 7.5 6.1 1.1 1 0 0 1 1 1 0 CDC45-like protein ERG4_ERG24 PF01222.12 AEO58172.1 - 1e-178 594.3 2.5 1.2e-178 594.1 1.7 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 AEO58172.1 - 1.2e-06 27.9 0.1 3.1e-06 26.6 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) LSM PF01423.17 AEO58173.1 - 1.9e-16 59.3 0.1 2.6e-16 58.9 0.1 1.2 1 0 0 1 1 1 1 LSM domain Glyco_hydro_3 PF00933.16 AEO58175.1 - 4.9e-95 317.9 0.0 9.3e-95 317.0 0.0 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 AEO58175.1 - 3.2e-58 196.9 1.6 7.2e-58 195.7 0.2 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 AEO58175.1 - 1.3e-15 57.0 0.0 3.1e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF1823 PF08853.6 AEO58175.1 - 0.16 11.7 0.0 7.6 6.3 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1823) MFS_1 PF07690.11 AEO58176.1 - 2.1e-19 69.4 16.6 3.1e-19 68.9 11.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 AEO58176.1 - 0.01 15.5 0.8 0.01 15.5 0.6 2.2 2 0 0 2 2 2 0 MFS_1 like family rve PF00665.21 AEO58177.1 - 0.053 13.6 0.0 0.059 13.4 0.0 1.1 1 0 0 1 1 1 0 Integrase core domain PIP5K PF01504.13 AEO58181.1 - 4.7e-33 114.3 0.0 6.1e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase ERCC4 PF02732.10 AEO58181.1 - 0.087 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 ERCC4 domain Git3 PF11710.3 AEO58182.1 - 2.1e-15 56.8 14.3 6.6e-15 55.2 9.9 1.7 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 PALP PF00291.20 AEO58183.1 - 3.1e-61 207.2 0.1 3.9e-61 206.9 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 AEO58183.1 - 3.5e-09 36.3 0.0 3e-07 30.1 0.0 2.6 2 0 0 2 2 2 1 CBS domain AAA_19 PF13245.1 AEO58183.1 - 0.11 12.3 1.7 0.34 10.6 0.8 2.0 2 0 0 2 2 2 0 Part of AAA domain Ank PF00023.25 AEO58184.1 - 5.8e-37 123.6 1.5 6.2e-08 32.0 0.0 5.7 5 0 0 5 5 5 5 Ankyrin repeat zf-DHHC PF01529.15 AEO58184.1 - 7.5e-37 126.3 6.4 1.7e-36 125.2 4.4 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase Ank_2 PF12796.2 AEO58184.1 - 2.7e-34 117.3 0.1 1.4e-16 60.5 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 AEO58184.1 - 2.8e-26 90.9 1.7 3.2e-07 30.3 0.0 5.1 1 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 AEO58184.1 - 3.7e-23 81.4 1.9 3.3e-07 30.6 0.3 3.8 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 AEO58184.1 - 6.4e-23 78.5 3.6 1.6e-06 27.8 0.0 6.4 6 0 0 6 6 6 4 Ankyrin repeat Mannosyl_trans3 PF11051.3 AEO58185.1 - 0.00025 20.4 0.0 0.00042 19.7 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Glyco_transf_8 PF01501.15 AEO58185.1 - 0.00047 19.5 3.1 0.0012 18.2 2.2 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 8 Asp PF00026.18 AEO58186.1 - 3.1e-08 33.2 0.0 5.1e-08 32.5 0.0 1.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease DUF2051 PF09738.4 AEO58187.1 - 0.3 10.3 3.2 0.47 9.6 2.2 1.2 1 0 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) Acyl_transf_3 PF01757.17 AEO58188.1 - 1.4e-31 109.6 29.7 1.9e-31 109.1 20.6 1.2 1 0 0 1 1 1 1 Acyltransferase family DUF3446 PF11928.3 AEO58189.1 - 0.025 14.7 4.8 0.05 13.8 3.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) UDPG_MGDP_dh PF00984.14 AEO58191.1 - 1.2e-21 76.7 0.0 2.1e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.10 AEO58191.1 - 2e-13 50.4 0.0 3.4e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NicO PF03824.11 AEO58193.1 - 5.3e-66 222.8 8.2 7e-66 222.4 5.7 1.2 1 0 0 1 1 1 1 High-affinity nickel-transport protein DUF1183 PF06682.7 AEO58193.1 - 0.13 11.8 0.0 0.3 10.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) DUF3040 PF11239.3 AEO58193.1 - 0.41 10.7 0.0 0.41 10.7 0.0 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3040) FTA2 PF13095.1 AEO58194.1 - 3.2e-29 102.0 0.0 4.3e-29 101.6 0.0 1.1 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Flavi_NS2B PF01002.14 AEO58195.1 - 0.12 11.9 0.1 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Flavivirus non-structural protein NS2B Glyco_hydro_7 PF00840.15 AEO58196.1 - 2.2e-128 428.3 10.0 6.6e-127 423.4 7.0 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.13 AEO58196.1 - 2e-13 49.7 13.2 2e-13 49.7 9.1 3.0 2 0 0 2 2 2 1 Fungal cellulose binding domain MFS_1 PF07690.11 AEO58197.1 - 2.5e-36 125.1 28.5 3.3e-36 124.7 18.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Med3 PF11593.3 AEO58198.1 - 0.098 11.8 3.5 0.15 11.2 2.4 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PAT1 PF09770.4 AEO58198.1 - 1.6 6.8 17.1 2.2 6.4 11.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Fungal_trans PF04082.13 AEO58199.1 - 2.9e-23 82.0 0.8 3.8e-23 81.6 0.5 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO58199.1 - 1.1e-07 31.6 5.3 1.7e-07 30.9 3.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OmdA PF13376.1 AEO58200.1 - 1.1e-23 82.6 1.1 1.1e-23 82.6 0.8 1.8 2 0 0 2 2 2 1 Bacteriocin-protection, YdeI or OmpD-Associated DPPIV_N PF00930.16 AEO58201.1 - 1.8e-107 358.9 1.0 2.2e-107 358.7 0.1 1.5 2 0 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 AEO58201.1 - 5.9e-39 133.4 0.3 1.1e-38 132.6 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 AEO58201.1 - 1.2e-06 28.2 0.4 6.1e-06 26.0 0.3 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 AEO58201.1 - 0.0089 15.6 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold MFS_1 PF07690.11 AEO58202.1 - 3.6e-38 131.1 26.9 5.6e-38 130.5 18.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO58202.1 - 1.2e-12 47.1 17.7 1.9e-12 46.5 12.0 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.2 AEO58202.1 - 0.021 14.6 0.5 0.089 12.5 0.3 2.1 1 0 0 1 1 1 0 MFS_1 like family DUF486 PF04342.7 AEO58202.1 - 0.11 12.5 7.7 0.1 12.6 1.4 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF486 Hyccin PF09790.4 AEO58202.1 - 0.23 10.2 0.0 3.2 6.5 0.0 2.0 2 0 0 2 2 2 0 Hyccin UNC-93 PF05978.11 AEO58202.1 - 0.78 9.2 7.6 0.073 12.5 1.3 2.1 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 GSK-3_bind PF05350.7 AEO58204.1 - 0.058 12.8 0.1 0.058 12.8 0.1 1.2 1 0 0 1 1 1 0 Glycogen synthase kinase-3 binding Response_reg PF00072.19 AEO58205.1 - 7.7e-19 67.7 0.0 1.1e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Turandot PF07240.6 AEO58205.1 - 0.13 11.7 0.0 7 6.2 0.0 2.3 2 0 0 2 2 2 0 Stress-inducible humoral factor Turandot TPR_10 PF13374.1 AEO58205.1 - 0.76 9.7 2.9 23 5.0 0.2 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat WD40 PF00400.27 AEO58206.1 - 9.9e-16 56.9 0.5 1.6e-08 34.0 0.0 2.0 2 0 0 2 2 2 2 WD domain, G-beta repeat PD40 PF07676.7 AEO58206.1 - 0.0074 15.9 0.1 3.3 7.4 0.0 2.3 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat DUF1996 PF09362.5 AEO58207.1 - 2.5e-78 262.9 0.1 3.6e-78 262.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) CBM_1 PF00734.13 AEO58207.1 - 5.1e-12 45.2 18.6 5.1e-12 45.2 12.9 2.5 2 0 0 2 2 2 1 Fungal cellulose binding domain WD40 PF00400.27 AEO58208.1 - 1.4e-43 145.2 18.4 1e-09 37.8 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 AEO58208.1 - 1.6e-09 37.3 0.7 3.5e-09 36.2 0.5 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 AEO58208.1 - 2.5e-08 33.3 0.1 5.9e-08 32.1 0.0 1.7 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 AEO58208.1 - 7.5e-07 27.6 3.5 0.4 8.7 0.0 4.5 2 1 2 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 AEO58208.1 - 4.7e-06 25.6 0.1 0.0066 15.2 0.1 2.6 2 1 0 2 2 2 2 Nup133 N terminal like PQQ_2 PF13360.1 AEO58208.1 - 0.0014 18.1 0.1 0.003 17.0 0.1 1.5 1 0 0 1 1 1 1 PQQ-like domain Cytochrom_D1 PF02239.11 AEO58208.1 - 0.0072 14.6 0.0 0.013 13.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain Pectate_lyase_3 PF12708.2 AEO58209.1 - 6.9e-89 297.8 14.3 3.6e-72 243.1 6.4 2.4 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 AEO58209.1 - 4.7e-07 29.1 2.4 0.0074 15.7 0.1 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase NosD PF05048.8 AEO58209.1 - 0.0019 17.4 3.9 0.004 16.3 2.7 1.5 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Beta_helix PF13229.1 AEO58209.1 - 0.002 17.8 9.6 0.0053 16.5 6.7 1.8 1 0 0 1 1 1 1 Right handed beta helix region Scs3p PF10261.4 AEO58210.1 - 4.8e-67 225.4 6.5 5.9e-67 225.1 4.5 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Cation_efflux PF01545.16 AEO58210.1 - 0.0058 15.7 0.7 0.0083 15.2 0.5 1.2 1 0 0 1 1 1 1 Cation efflux family ATP_transf PF09830.4 AEO58211.1 - 6.8e-16 57.8 0.0 1.4e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 ATP adenylyltransferase TFIIF_alpha PF05793.7 AEO58212.1 - 6.7 4.9 5.0 13 4.0 3.5 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) MFS_1 PF07690.11 AEO58214.1 - 9.5e-45 152.8 38.9 9.5e-45 152.8 26.9 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO58214.1 - 9.2e-13 47.5 12.5 9.2e-13 47.5 8.6 1.8 2 1 0 2 2 2 1 Sugar (and other) transporter p450 PF00067.17 AEO58215.1 - 3e-64 217.2 0.0 4.5e-64 216.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Amidoligase_2 PF12224.3 AEO58219.1 - 4.5e-29 101.8 0.1 1.2e-28 100.4 0.1 1.6 1 1 0 1 1 1 1 Putative amidoligase enzyme Tautomerase_3 PF14832.1 AEO58220.1 - 2.6e-48 163.4 0.0 3.1e-48 163.2 0.0 1.1 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Tautomerase PF01361.16 AEO58220.1 - 0.0061 16.1 0.0 1.6 8.4 0.0 2.3 2 0 0 2 2 2 2 Tautomerase enzyme DUF1996 PF09362.5 AEO58221.1 - 3.8e-50 170.7 1.9 4.7e-50 170.4 1.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Gal_mutarotas_2 PF13802.1 AEO58221.1 - 0.086 12.7 0.3 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Galactose mutarotase-like BSP_II PF05432.6 AEO58222.1 - 0.0061 15.8 8.8 0.01 15.1 6.1 1.3 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) RNA_pol_Rpc4 PF05132.9 AEO58222.1 - 0.051 13.5 0.6 0.2 11.6 0.5 1.9 2 0 0 2 2 2 0 RNA polymerase III RPC4 Cwf_Cwc_15 PF04889.7 AEO58222.1 - 0.073 12.7 8.7 0.15 11.7 6.1 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PBP1_TM PF14812.1 AEO58222.1 - 0.15 12.3 11.0 0.17 12.2 5.3 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2722 PF10846.3 AEO58222.1 - 0.62 9.0 6.7 0.023 13.7 0.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) FAM176 PF14851.1 AEO58222.1 - 1.1 8.8 7.4 3.6 7.2 5.1 1.8 1 0 0 1 1 1 0 FAM176 family Myc_N PF01056.13 AEO58222.1 - 1.9 7.5 8.1 3.2 6.8 5.6 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Sporozoite_P67 PF05642.6 AEO58222.1 - 3.2 5.5 9.3 4.4 5.0 6.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen YqfQ PF14181.1 AEO58222.1 - 3.3 7.7 5.5 7.3 6.6 3.8 1.5 1 0 0 1 1 1 0 YqfQ-like protein SnoaL_2 PF12680.2 AEO58222.1 - 4.3 7.8 7.1 1.1 9.7 0.5 2.7 2 1 1 3 3 3 0 SnoaL-like domain CENP-B_dimeris PF09026.5 AEO58222.1 - 4.4 7.6 21.8 0.5 10.6 11.0 2.4 3 0 0 3 3 2 0 Centromere protein B dimerisation domain Daxx PF03344.10 AEO58222.1 - 7.5 4.9 19.9 12 4.1 13.8 1.2 1 0 0 1 1 1 0 Daxx Family Mucin PF01456.12 AEO58223.1 - 5.2 6.8 38.7 5.8 6.6 26.8 1.3 1 1 0 1 1 1 0 Mucin-like glycoprotein DUF1387 PF07139.6 AEO58223.1 - 9.3 5.7 7.4 12 5.3 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Nuc_sug_transp PF04142.10 AEO58226.1 - 6.7e-20 71.2 0.4 1.1e-19 70.4 0.2 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter Tmemb_40 PF10160.4 AEO58226.1 - 0.1 11.7 0.3 0.24 10.6 0.0 1.7 2 1 1 3 3 3 0 Predicted membrane protein FSH1 PF03959.8 AEO58227.1 - 1.4e-24 86.7 0.0 1.6e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 AEO58227.1 - 3.3e-12 46.8 0.2 8.6e-09 35.6 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO58227.1 - 1.1e-06 28.4 0.0 2e-06 27.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 AEO58227.1 - 1.6e-05 25.2 0.0 2e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_2 PF02230.11 AEO58227.1 - 0.00025 20.5 0.0 0.00067 19.1 0.0 1.6 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase PGAP1 PF07819.8 AEO58227.1 - 0.0035 16.9 0.0 0.027 14.0 0.0 2.0 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.8 AEO58227.1 - 0.029 13.9 0.0 0.073 12.6 0.0 1.8 1 1 1 2 2 2 0 alpha/beta hydrolase fold DUF2305 PF10230.4 AEO58227.1 - 0.093 12.1 0.0 0.3 10.4 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) Abhydrolase_1 PF00561.15 AEO58227.1 - 0.14 11.7 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ish1 PF10281.4 AEO58228.1 - 0.036 14.1 0.0 0.063 13.3 0.0 1.4 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein DZR PF12773.2 AEO58229.1 - 0.023 14.4 7.5 0.48 10.2 1.0 2.3 2 0 0 2 2 2 0 Double zinc ribbon zf-C4pol PF14260.1 AEO58229.1 - 0.17 11.9 3.8 6.8 6.7 0.1 2.3 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta NOB1_Zn_bind PF08772.6 AEO58229.1 - 5.8 6.8 6.1 15 5.4 0.5 2.4 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like DUF805 PF05656.9 AEO58230.1 - 1.7 8.4 7.3 3.8 7.3 5.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF805) DLH PF01738.13 AEO58231.1 - 6.7e-28 97.4 0.0 7.8e-28 97.2 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 AEO58231.1 - 5.9e-08 32.5 0.0 8.4e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AEO58231.1 - 0.0021 17.9 0.3 0.011 15.6 0.2 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO58231.1 - 0.073 12.6 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Acyl_transf_3 PF01757.17 AEO58232.1 - 3.1e-26 92.0 16.8 4.5e-26 91.4 11.6 1.3 1 0 0 1 1 1 1 Acyltransferase family MFS_1 PF07690.11 AEO58235.1 - 3.4e-29 101.6 33.0 6.5e-29 100.7 21.9 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO58235.1 - 5.4e-09 35.1 9.4 5.4e-09 35.1 6.5 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 AEO58235.1 - 0.0025 15.9 0.5 0.0025 15.9 0.4 2.0 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family MFS_Mycoplasma PF07672.8 AEO58235.1 - 2.2 7.4 9.1 0.58 9.2 0.5 2.6 1 1 1 3 3 3 0 Mycoplasma MFS transporter WD40 PF00400.27 AEO58236.1 - 2.7e-57 188.7 15.7 1.1e-09 37.7 0.1 8.3 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 AEO58236.1 - 4.5e-10 39.1 0.2 1.9e-09 37.1 0.1 2.1 2 0 0 2 2 2 1 F-box-like Nup160 PF11715.3 AEO58236.1 - 2.4e-09 35.8 1.7 0.042 11.9 0.0 4.1 2 1 1 4 4 4 3 Nucleoporin Nup120/160 F-box PF00646.28 AEO58236.1 - 1.3e-08 34.2 0.0 1e-07 31.4 0.0 2.3 1 1 1 2 2 2 1 F-box domain YmzC PF14157.1 AEO58236.1 - 0.03 14.1 1.1 77 3.2 0.1 4.6 4 1 0 5 5 5 0 YmzC-like protein Mito_carr PF00153.22 AEO58237.1 - 1.3e-70 233.1 2.9 2.4e-22 78.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Terpene_synth_C PF03936.11 AEO58238.1 - 2.1e-09 37.0 0.0 2.5e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain p450 PF00067.17 AEO58239.1 - 1.2e-42 146.0 0.0 1.4e-32 112.8 0.0 2.3 2 1 0 2 2 2 2 Cytochrome P450 DUF2721 PF11026.3 AEO58240.1 - 2.1 7.9 6.1 4.6 6.8 4.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) ABC2_membrane_3 PF12698.2 AEO58240.1 - 9.1 5.1 9.6 12 4.7 6.7 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Dynamin_N PF00350.18 AEO58242.1 - 1.7e-35 122.3 0.0 3.5e-35 121.2 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 AEO58242.1 - 2.9e-16 59.0 0.0 2e-13 49.7 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.18 AEO58242.1 - 3.6e-05 23.7 0.0 0.00041 20.2 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 AEO58242.1 - 0.03 14.7 0.0 0.093 13.2 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein AAA_21 PF13304.1 AEO58242.1 - 0.034 14.1 0.1 0.084 12.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain DUF3733 PF12534.3 AEO58244.1 - 2.6 7.4 8.9 0.45 9.8 1.0 2.9 2 0 0 2 2 2 0 Leucine-rich repeat containing protein 8 DUF373 PF04123.8 AEO58244.1 - 7.3 5.5 12.8 0.62 9.0 5.1 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF373) Med20 PF08612.6 AEO58245.1 - 0.066 12.3 0.0 0.087 11.9 0.0 1.1 1 0 0 1 1 1 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex GAGA_bind PF06217.7 AEO58246.1 - 0.00052 20.0 0.7 0.00059 19.9 0.5 1.0 1 0 0 1 1 1 1 GAGA binding protein-like family WTF PF03303.8 AEO58246.1 - 0.21 10.9 1.0 0.32 10.3 0.7 1.2 1 0 0 1 1 1 0 WTF protein DUF4106 PF13388.1 AEO58246.1 - 1 8.2 6.6 1.2 7.9 4.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) MIP-T3 PF10243.4 AEO58246.1 - 1.1 7.6 22.8 1.4 7.3 15.8 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF4407 PF14362.1 AEO58246.1 - 2.2 7.1 4.3 2.6 6.9 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1510 PF07423.6 AEO58246.1 - 2.7 7.2 11.4 3.2 7.0 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) U79_P34 PF03064.11 AEO58246.1 - 3 7.3 12.1 3.5 7.0 8.4 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 RR_TM4-6 PF06459.7 AEO58246.1 - 3.2 7.5 13.1 4 7.2 9.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Sec62 PF03839.11 AEO58246.1 - 4.1 6.7 10.6 5.3 6.3 7.3 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DDHD PF02862.12 AEO58246.1 - 4.9 6.8 6.5 5.9 6.6 4.5 1.1 1 0 0 1 1 1 0 DDHD domain NARP1 PF12569.3 AEO58246.1 - 5.8 5.5 15.1 7.3 5.2 10.5 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Borrelia_P83 PF05262.6 AEO58246.1 - 7 4.7 12.5 8.1 4.5 8.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF2413 PF10310.4 AEO58246.1 - 7.3 5.2 11.6 8.5 5.0 8.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Esterase_phd PF10503.4 AEO58247.1 - 3.3e-22 78.8 0.1 4.6e-22 78.3 0.1 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 AEO58247.1 - 3.2e-10 39.5 0.5 4.5e-10 39.1 0.3 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 AEO58247.1 - 2e-07 30.8 0.1 2.8e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AEO58247.1 - 2e-05 24.6 0.0 3.3e-05 23.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 AEO58247.1 - 0.00015 20.6 2.0 0.00041 19.1 0.3 2.0 2 0 0 2 2 2 1 Carboxylesterase family Esterase PF00756.15 AEO58247.1 - 0.00048 19.6 0.4 0.00074 19.0 0.3 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.15 AEO58247.1 - 0.01 15.3 0.1 0.014 14.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 AEO58247.1 - 0.018 14.6 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold IncA PF04156.9 AEO58249.1 - 0.13 11.8 0.1 0.3 10.6 0.1 1.5 1 0 0 1 1 1 0 IncA protein Reo_sigmaC PF04582.7 AEO58250.1 - 1.9e-05 24.0 18.6 2.4e-05 23.7 6.1 2.8 1 1 0 2 2 2 1 Reovirus sigma C capsid protein Spc7 PF08317.6 AEO58250.1 - 2.6e-05 23.0 24.0 2.6e-05 23.0 16.6 2.9 1 1 2 3 3 3 1 Spc7 kinetochore protein Myosin_tail_1 PF01576.14 AEO58250.1 - 7.1e-05 20.7 79.2 7.3e-05 20.7 16.9 2.8 1 1 0 2 2 2 2 Myosin tail Tropomyosin PF00261.15 AEO58250.1 - 0.00011 21.4 13.5 0.00011 21.4 9.4 3.0 1 1 2 3 3 2 2 Tropomyosin GAS PF13851.1 AEO58250.1 - 0.0032 16.7 15.9 0.0032 16.7 11.0 3.8 1 1 2 3 3 3 2 Growth-arrest specific micro-tubule binding IncA PF04156.9 AEO58250.1 - 0.0048 16.5 31.0 0.0048 16.5 21.5 4.1 1 1 1 2 2 1 1 IncA protein DUF2968 PF11180.3 AEO58250.1 - 0.0064 15.8 19.1 0.0064 15.8 13.2 4.4 1 1 4 5 5 2 1 Protein of unknown function (DUF2968) Tup_N PF08581.5 AEO58250.1 - 0.0072 16.4 2.1 0.0072 16.4 1.4 5.6 3 1 2 5 5 5 2 Tup N-terminal zf-C4H2 PF10146.4 AEO58250.1 - 0.01 15.8 17.1 0.01 15.8 11.9 2.5 1 1 1 2 2 1 0 Zinc finger-containing protein TMF_DNA_bd PF12329.3 AEO58250.1 - 0.012 15.3 17.0 0.012 15.3 11.8 6.4 1 1 5 6 6 5 0 TATA element modulatory factor 1 DNA binding M_domain PF12938.2 AEO58250.1 - 0.36 10.5 9.3 0.017 14.9 1.7 2.2 2 0 0 2 2 2 0 M domain of GW182 AAA_13 PF13166.1 AEO58250.1 - 2.2 6.6 62.5 0.48 8.8 30.1 2.6 1 1 1 2 2 1 0 AAA domain CENP-F_leu_zip PF10473.4 AEO58250.1 - 2.8 7.8 72.7 0.021 14.6 14.4 4.5 1 1 3 4 4 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF812 PF05667.6 AEO58250.1 - 4.2 5.7 60.2 0.44 9.0 23.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DUF3584 PF12128.3 AEO58250.1 - 5.6 4.1 70.4 0.61 7.3 44.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) HrpB7 PF09486.5 AEO58250.1 - 8.5 6.2 69.0 0.48 10.3 4.5 5.3 2 1 2 5 5 5 0 Bacterial type III secretion protein (HrpB7) ATG16 PF08614.6 AEO58250.1 - 9.1 6.0 61.1 0.054 13.3 4.6 3.9 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DUF2360 PF10152.4 AEO58251.1 - 0.061 13.6 3.2 0.07 13.4 2.2 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Peptidase_M20 PF01546.23 AEO58252.1 - 2.7e-28 98.7 0.0 3.6e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 AEO58252.1 - 1.4e-14 53.7 0.0 3.4e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 AEO58252.1 - 0.0011 18.7 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 DUF4448 PF14610.1 AEO58253.1 - 0.0082 15.6 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF4245 PF14030.1 AEO58253.1 - 0.031 14.0 0.2 0.056 13.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4245) DUF2370 PF10176.4 AEO58253.1 - 0.22 10.8 2.5 1.6 7.9 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2370) VPEP PF07589.6 AEO58253.1 - 3.8 7.5 6.3 11 6.1 0.3 2.4 2 0 0 2 2 2 0 PEP-CTERM motif BSP_II PF05432.6 AEO58253.1 - 3.9 6.6 9.6 2.7 7.1 0.1 2.2 1 1 0 2 2 2 0 Bone sialoprotein II (BSP-II) GFA PF04828.9 AEO58254.1 - 2.4e-18 65.8 8.8 7e-10 38.7 0.0 3.2 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme Galanin PF01296.13 AEO58255.1 - 0.075 12.8 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 Galanin Abhydrolase_3 PF07859.8 AEO58256.1 - 2.9e-32 111.9 0.2 6.1e-32 110.9 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AEO58256.1 - 2.6e-06 27.2 0.1 3.8e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 AEO58256.1 - 1.8e-05 23.3 0.1 7.7e-05 21.3 0.0 1.7 1 1 0 2 2 2 1 Acetyl xylan esterase (AXE1) COesterase PF00135.23 AEO58256.1 - 5.1e-05 22.1 0.0 0.012 14.3 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Peptidase_S9 PF00326.16 AEO58256.1 - 0.00034 19.8 0.0 0.00062 19.0 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.4 AEO58256.1 - 0.11 11.7 2.7 0.08 12.1 0.4 1.8 2 1 0 2 2 2 0 Esterase PHB depolymerase Pkinase PF00069.20 AEO58257.1 - 3.5e-18 65.6 0.0 4.3e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO58257.1 - 1.9e-17 63.2 0.0 7.1e-17 61.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO58257.1 - 0.00019 20.5 0.0 0.00028 19.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 AEO58257.1 - 0.011 14.8 0.0 0.015 14.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_hydro_31 PF01055.21 AEO58258.1 - 1.3e-93 314.2 4.4 1.7e-93 313.8 3.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Clr5 PF14420.1 AEO58259.1 - 4.6e-21 74.4 2.2 1.1e-20 73.2 1.5 1.7 1 0 0 1 1 1 1 Clr5 domain NmrA PF05368.8 AEO58261.1 - 1.3e-23 83.4 0.1 1.7e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 AEO58261.1 - 7e-12 45.7 0.3 1.4e-11 44.7 0.2 1.5 1 0 0 1 1 1 1 NADH(P)-binding Nup35_RRM PF05172.8 AEO58261.1 - 0.0093 15.6 0.0 0.02 14.5 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Aldo_ket_red PF00248.16 AEO58262.1 - 1e-56 191.8 0.0 1.2e-56 191.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Hydrolase_6 PF13344.1 AEO58263.1 - 6.1e-21 74.2 0.0 1.2e-20 73.2 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 AEO58263.1 - 1.2e-19 69.7 0.0 3.2e-19 68.4 0.0 1.8 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 AEO58263.1 - 2.6e-05 24.5 0.0 0.013 15.7 0.0 2.5 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 AEO58263.1 - 0.0036 17.7 0.0 0.027 14.8 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3574 PF12098.3 AEO58264.1 - 0.026 14.1 0.0 0.065 12.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3574) NAD_binding_10 PF13460.1 AEO58265.1 - 1.9e-11 44.2 0.1 2.9e-11 43.7 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding GCOM2 PF15328.1 AEO58266.1 - 0.00031 20.5 2.1 0.004 16.9 1.0 2.1 2 0 0 2 2 2 1 Putative GRINL1B complex locus protein 2 ADIP PF11559.3 AEO58266.1 - 0.0013 18.6 11.6 0.093 12.6 0.0 3.0 3 0 0 3 3 3 2 Afadin- and alpha -actinin-Binding HOOK PF05622.7 AEO58266.1 - 0.13 10.0 6.3 0.9 7.2 0.0 2.3 2 0 0 2 2 2 0 HOOK protein DUF3373 PF11853.3 AEO58266.1 - 0.15 10.5 1.3 0.18 10.2 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3373) DUF972 PF06156.8 AEO58266.1 - 0.18 12.1 3.9 4 7.8 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF972) TBPIP PF07106.8 AEO58266.1 - 0.18 11.3 9.1 0.88 9.0 1.9 2.3 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CENP-F_leu_zip PF10473.4 AEO58266.1 - 0.33 10.8 9.6 0.27 11.0 1.3 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 AEO58266.1 - 0.58 9.7 9.6 2.7 7.5 0.3 2.3 2 0 0 2 2 2 0 IncA protein DivIC PF04977.10 AEO58266.1 - 0.88 9.0 13.7 0.42 10.1 4.6 2.4 2 0 0 2 2 2 0 Septum formation initiator Spc24 PF08286.6 AEO58266.1 - 0.95 9.1 6.2 3.7 7.2 0.0 2.5 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF2802 PF10975.3 AEO58266.1 - 2 8.2 7.2 1.4 8.6 1.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) ERM PF00769.14 AEO58266.1 - 3.7 7.0 13.9 0.48 9.9 0.4 2.9 3 0 0 3 3 3 0 Ezrin/radixin/moesin family Viral_P18 PF04521.8 AEO58266.1 - 3.7 6.9 6.5 8.9 5.7 0.1 2.5 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein DUF3847 PF12958.2 AEO58266.1 - 4.2 7.2 14.4 3.1 7.6 3.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) Prefoldin_2 PF01920.15 AEO58266.1 - 9.1 6.1 13.0 4.8 7.0 4.0 2.6 2 0 0 2 2 2 0 Prefoldin subunit XhlA PF10779.4 AEO58266.1 - 9.9 6.1 9.7 20 5.1 2.1 2.5 2 0 0 2 2 2 0 Haemolysin XhlA FlgN PF05130.7 AEO58267.1 - 0.0051 17.0 1.4 0.0081 16.4 1.0 1.4 1 0 0 1 1 1 1 FlgN protein APG6 PF04111.7 AEO58267.1 - 0.0056 15.7 0.5 0.0069 15.4 0.3 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 OmpH PF03938.9 AEO58267.1 - 0.036 13.9 0.4 0.047 13.6 0.3 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1599 PF07659.6 AEO58267.1 - 0.086 12.9 2.6 5.7 7.0 0.1 2.3 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1599) DUF1664 PF07889.7 AEO58267.1 - 0.15 11.8 0.3 0.23 11.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Fzo_mitofusin PF04799.8 AEO58267.1 - 0.2 11.0 1.1 0.29 10.5 0.8 1.2 1 0 0 1 1 1 0 fzo-like conserved region DUF724 PF05266.9 AEO58267.1 - 0.22 11.1 3.0 0.61 9.6 2.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF724) CALCOCO1 PF07888.6 AEO58267.1 - 1.5 7.0 9.3 1.9 6.7 6.5 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2852 PF11014.3 AEO58267.1 - 2.5 8.0 6.2 2.6 8.0 3.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) W2 PF02020.13 AEO58269.1 - 0.014 15.2 2.3 18 5.3 0.1 3.7 1 1 2 3 3 3 0 eIF4-gamma/eIF5/eIF2-epsilon DUF2555 PF10742.4 AEO58269.1 - 6.7 6.4 7.0 43 3.8 0.2 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF2555) Abhydrolase_6 PF12697.2 AEO58271.1 - 1.5e-25 90.4 0.1 1.9e-25 90.1 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO58271.1 - 2.2e-20 73.2 0.0 3.5e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AEO58271.1 - 1.9e-10 40.6 0.0 1.3e-09 37.9 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 AEO58271.1 - 4.5e-06 25.3 0.0 8.7e-06 24.4 0.0 1.5 2 0 0 2 2 2 1 Ndr family RNA_pol_Rpo13 PF12136.3 AEO58272.1 - 0.084 12.5 4.6 4.5 7.0 0.0 2.4 2 0 0 2 2 2 0 RNA polymerase Rpo13 subunit HTH domain E1-E2_ATPase PF00122.15 AEO58273.1 - 6.8e-51 172.5 5.5 1.2e-50 171.6 3.8 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 AEO58273.1 - 2.1e-25 90.3 0.0 4.6e-25 89.2 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 AEO58273.1 - 1.3e-12 48.2 0.0 2.6e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 AEO58273.1 - 0.001 19.1 1.2 0.0038 17.3 0.1 2.4 2 0 0 2 2 2 1 Heavy-metal-associated domain Hydrolase_3 PF08282.7 AEO58273.1 - 0.0082 15.7 0.1 0.063 12.8 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Peptidase_S10 PF00450.17 AEO58273.1 - 0.2 10.7 0.0 0.3 10.1 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S6PP PF05116.8 AEO58273.1 - 0.35 10.1 0.4 41 3.3 0.1 3.0 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase Ank_2 PF12796.2 AEO58275.1 - 8.4e-41 138.2 0.9 4.2e-11 43.0 0.0 5.8 3 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 AEO58275.1 - 8.7e-31 104.1 9.3 2e-06 27.3 0.0 7.5 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.1 AEO58275.1 - 2.6e-24 82.8 8.9 0.00044 20.2 0.0 7.9 7 1 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.1 AEO58275.1 - 1.3e-20 73.3 1.5 1.4e-05 25.4 0.0 6.8 5 1 2 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 AEO58275.1 - 1.6e-19 69.4 10.6 0.0073 16.5 0.0 7.9 6 1 2 8 8 8 5 Ankyrin repeats (many copies) F-box-like PF12937.2 AEO58275.1 - 0.0025 17.5 0.0 0.0052 16.4 0.0 1.6 1 0 0 1 1 1 1 F-box-like Fip1 PF05182.8 AEO58276.1 - 2.4e-21 74.7 0.8 4.1e-21 73.9 0.5 1.4 1 0 0 1 1 1 1 Fip1 motif Nucleoporin_FG PF13634.1 AEO58277.1 - 1.5e-25 89.6 136.2 1.6e-15 57.3 33.9 3.6 2 1 2 4 4 4 3 Nucleoporin FG repeat region DUF3584 PF12128.3 AEO58277.1 - 0.0093 13.3 2.9 0.033 11.5 2.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3584) AbiH PF14253.1 AEO58277.1 - 0.02 14.5 0.0 0.3 10.6 0.0 2.0 2 0 0 2 2 2 0 Bacteriophage abortive infection AbiH Med4 PF10018.4 AEO58277.1 - 0.048 13.0 1.6 0.55 9.6 0.0 2.4 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF1192 PF06698.6 AEO58277.1 - 0.097 12.4 0.1 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) RNA_pol_3_Rpc31 PF11705.3 AEO58278.1 - 9.4e-11 42.0 36.6 6.4e-10 39.3 25.4 1.9 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Autophagy_N PF03986.8 AEO58278.1 - 7.1 6.3 9.4 10 5.8 6.5 1.2 1 0 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain Mito_fiss_reg PF05308.6 AEO58279.1 - 0.6 9.4 4.3 6.2 6.1 0.4 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator Sec7 PF01369.15 AEO58280.1 - 1.5e-64 217.1 0.8 1.5e-64 217.1 0.5 3.0 3 1 1 4 4 4 1 Sec7 domain Sec7_N PF12783.2 AEO58280.1 - 4.6e-55 185.6 2.1 4.6e-55 185.6 1.5 2.9 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 AEO58280.1 - 1.1e-33 114.5 2.1 5.8e-32 109.0 0.1 3.4 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) 2-oxoacid_dh PF00198.18 AEO58281.1 - 3.1e-76 255.6 0.0 4e-76 255.3 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 AEO58281.1 - 5.3e-18 64.4 1.3 1.3e-17 63.1 0.9 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 AEO58281.1 - 3.7e-11 42.4 1.4 6.3e-11 41.7 0.1 2.1 2 0 0 2 2 2 1 e3 binding domain DUF3614 PF12267.3 AEO58281.1 - 0.0014 18.9 0.9 0.0036 17.6 0.2 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF3614) APH PF01636.18 AEO58282.1 - 0.00061 19.6 2.8 0.0015 18.2 1.9 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF4135 PF13575.1 AEO58282.1 - 0.14 11.1 0.1 0.25 10.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Fungal_trans PF04082.13 AEO58283.1 - 1e-14 54.0 0.4 1.5e-14 53.5 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO58283.1 - 3.5e-08 33.2 11.6 6.1e-08 32.4 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_11 PF00457.12 AEO58284.1 - 5.1e-78 260.6 18.4 6e-78 260.4 12.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 SET PF00856.23 AEO58286.1 - 8.5e-11 42.4 0.0 1.7e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.13 AEO58286.1 - 0.00012 21.8 2.2 0.00012 21.8 1.5 2.2 2 0 0 2 2 2 1 MYND finger Sigma70_ner PF04546.8 AEO58287.1 - 0.13 11.9 2.7 1.1 8.7 0.0 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region Myc_N PF01056.13 AEO58287.1 - 0.47 9.5 1.9 5.5 6.0 0.0 2.3 2 0 0 2 2 2 0 Myc amino-terminal region CENP-B_dimeris PF09026.5 AEO58287.1 - 0.62 10.3 11.4 0.67 10.2 1.9 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 AEO58287.1 - 0.98 8.9 7.1 0.34 10.4 0.8 2.4 2 0 0 2 2 2 0 Nucleoplasmin Ferritin_2 PF13668.1 AEO58288.1 - 2e-15 56.9 0.0 3.8e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain p450 PF00067.17 AEO58289.1 - 5.7e-56 189.9 0.0 8.2e-56 189.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 2-Hacid_dh_C PF02826.14 AEO58290.1 - 8.6e-40 135.7 0.0 1.3e-20 73.3 0.0 3.1 3 0 0 3 3 3 3 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Aldolase_II PF00596.16 AEO58290.1 - 0.028 14.0 0.0 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 Class II Aldolase and Adducin N-terminal domain 2-Hacid_dh PF00389.25 AEO58290.1 - 0.076 12.4 0.0 0.085 12.3 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 3HCDH_N PF02737.13 AEO58290.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.20 AEO58291.1 - 3.2e-05 23.9 0.0 5.9e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO58291.1 - 0.00023 20.8 0.0 0.00039 20.1 0.0 1.4 1 0 0 1 1 1 1 KR domain ketoacyl-synt PF00109.21 AEO58293.1 - 1.7e-72 243.9 0.9 4.3e-72 242.6 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 AEO58293.1 - 1.1e-54 185.9 0.1 2e-54 185.1 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 AEO58293.1 - 1.1e-54 184.7 0.4 6e-54 182.4 0.0 2.6 3 0 0 3 3 3 1 KR domain PS-DH PF14765.1 AEO58293.1 - 1.2e-54 185.4 0.2 2.4e-54 184.5 0.1 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 AEO58293.1 - 9.2e-44 149.2 0.8 7.8e-42 143.0 0.0 3.4 3 0 0 3 3 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 AEO58293.1 - 2.8e-41 140.0 0.1 1.4e-40 137.8 0.1 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 AEO58293.1 - 2.1e-21 75.8 0.1 1e-20 73.5 0.1 2.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 AEO58293.1 - 3.8e-16 60.1 0.1 2e-15 57.8 0.1 2.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.20 AEO58293.1 - 2.7e-06 27.5 0.3 7.6e-06 26.0 0.2 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Saccharop_dh PF03435.13 AEO58293.1 - 4.1e-06 26.0 0.1 8.1e-06 25.0 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase Methyltransf_12 PF08242.7 AEO58293.1 - 4.3e-05 23.9 0.1 0.00016 22.0 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Polysacc_synt_2 PF02719.10 AEO58293.1 - 0.00049 19.0 0.5 0.0011 17.9 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short_C2 PF13561.1 AEO58293.1 - 0.0006 19.6 0.0 0.0022 17.7 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Thiolase_N PF00108.18 AEO58293.1 - 0.00074 18.5 0.1 0.0016 17.4 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain CoA_trans PF01144.18 AEO58293.1 - 0.0011 18.1 0.1 1.5 7.9 0.0 2.4 2 0 0 2 2 2 2 Coenzyme A transferase NAD_binding_10 PF13460.1 AEO58293.1 - 0.0015 18.5 0.5 0.9 9.5 0.0 2.7 2 0 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 AEO58293.1 - 0.0061 15.2 0.0 0.01 14.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.15 AEO58293.1 - 0.017 15.2 0.0 0.059 13.4 0.0 1.9 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 AEO58293.1 - 0.025 14.0 0.1 0.09 12.2 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 AEO58293.1 - 0.092 13.1 3.8 0.12 12.7 0.0 3.0 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent dTMP_synthase PF02593.9 AEO58293.1 - 0.25 10.6 0.0 7 5.9 0.0 2.2 2 0 0 2 2 2 0 Thymidylate synthase Ubie_methyltran PF01209.13 AEO58293.1 - 0.26 10.3 0.0 4.3 6.3 0.0 2.2 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family DUF3632 PF12311.3 AEO58294.1 - 6.8e-24 84.6 0.0 9.6e-24 84.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) BASP1 PF05466.7 AEO58294.1 - 0.58 9.9 8.8 0.83 9.4 6.1 1.1 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) GHL12 PF14882.1 AEO58294.1 - 7.9 6.6 9.6 3.1 7.9 0.1 3.4 3 0 0 3 3 3 0 Hypothetical glycosyl hydrolase 12 Fungal_trans PF04082.13 AEO58296.1 - 1.1e-21 76.8 0.1 1.7e-21 76.2 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO58296.1 - 3e-09 36.6 9.0 5.4e-09 35.8 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PDGF PF00341.12 AEO58298.1 - 0.011 15.8 0.1 0.013 15.6 0.1 1.2 1 0 0 1 1 1 0 PDGF/VEGF domain Glyco_hydro_18 PF00704.23 AEO58299.1 - 6.6e-100 334.8 3.0 7.6e-100 334.6 2.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3704 PF12488.3 AEO58299.1 - 0.034 13.7 0.5 0.13 11.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3704) CbtA PF09490.5 AEO58299.1 - 0.097 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) Pkinase PF00069.20 AEO58300.1 - 5.2e-19 68.4 0.0 1.3e-17 63.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO58300.1 - 1.1e-05 24.6 0.0 0.00036 19.6 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO58300.1 - 0.014 14.3 0.0 0.038 12.9 0.0 1.6 1 1 0 1 1 1 0 Kinase-like Kdo PF06293.9 AEO58300.1 - 0.035 13.1 0.1 0.13 11.3 0.0 1.9 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Phage_fiber_2 PF03406.8 AEO58300.1 - 0.068 12.8 0.2 0.15 11.7 0.2 1.5 1 0 0 1 1 1 0 Phage tail fibre repeat APH PF01636.18 AEO58301.1 - 4.2e-18 65.9 0.1 1.1e-10 41.6 0.0 2.1 1 1 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 AEO58301.1 - 1.1e-09 38.2 0.0 1.4e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 AEO58301.1 - 0.00058 18.9 0.0 0.00091 18.2 0.0 1.3 1 0 0 1 1 1 1 Fructosamine kinase DUF1679 PF07914.6 AEO58301.1 - 0.00094 17.9 0.1 0.043 12.4 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) PI3K_rbd PF00794.13 AEO58301.1 - 0.017 15.0 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 PI3-kinase family, ras-binding domain Pkinase PF00069.20 AEO58301.1 - 0.021 14.0 0.0 0.59 9.2 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain RIO1 PF01163.17 AEO58301.1 - 0.027 13.8 0.1 1.8 7.9 0.1 2.1 2 0 0 2 2 2 0 RIO1 family Pkinase_Tyr PF07714.12 AEO58301.1 - 0.033 13.2 0.0 0.08 12.0 0.0 1.5 1 1 0 1 1 1 0 Protein tyrosine kinase zf-C2HC5 PF06221.8 AEO58302.1 - 6.1e-23 80.3 5.1 9.4e-23 79.7 3.6 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type SIR2 PF02146.12 AEO58303.1 - 7.7e-31 107.1 0.0 4e-09 36.4 0.0 3.3 3 0 0 3 3 3 3 Sir2 family zf-RING_3 PF14369.1 AEO58303.1 - 0.21 11.5 1.1 0.91 9.5 0.8 2.1 1 0 0 1 1 1 0 zinc-finger Glyco_hydro_43 PF04616.9 AEO58304.1 - 1.1e-18 67.3 3.0 1.7e-18 66.7 2.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Peptidase_S8 PF00082.17 AEO58306.1 - 8e-05 21.9 0.0 8e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Subtilase family Pro-kuma_activ PF09286.6 AEO58307.1 - 1.9e-29 102.5 0.0 3.5e-29 101.6 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Na_H_Exchanger PF00999.16 AEO58308.1 - 1e-28 99.9 43.9 5.6e-20 71.2 13.7 2.0 2 0 0 2 2 2 2 Sodium/hydrogen exchanger family DUF1467 PF07330.7 AEO58308.1 - 0.014 15.1 0.7 0.59 9.9 0.0 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1467) Fst_toxin PF13955.1 AEO58308.1 - 0.054 13.1 0.8 0.054 13.1 0.6 4.0 4 0 0 4 4 4 0 Toxin Fst, type I toxin-antitoxin system DUF1434 PF07254.7 AEO58308.1 - 0.093 12.5 1.0 0.21 11.4 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1434) RAP1 PF07218.6 AEO58309.1 - 9.2 4.2 6.8 11 4.0 4.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) EphA2_TM PF14575.1 AEO58310.1 - 0.05 13.9 0.7 30 5.0 0.0 4.1 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain Cytochrom_B_N PF00033.14 AEO58310.1 - 0.064 12.5 8.7 2.3 7.5 1.8 3.6 3 0 0 3 3 3 0 Cytochrome b(N-terminal)/b6/petB HemY_N PF07219.8 AEO58310.1 - 0.25 10.8 0.0 0.25 10.8 0.0 4.4 3 2 1 4 4 4 0 HemY protein N-terminus Herpes_gE PF02480.11 AEO58310.1 - 0.97 7.6 3.4 6.9 4.8 0.0 2.3 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E PLAC8 PF04749.12 AEO58312.1 - 2.3e-19 69.9 13.7 2.9e-19 69.5 9.5 1.1 1 0 0 1 1 1 1 PLAC8 family Ldh_1_N PF00056.18 AEO58314.1 - 6.1e-44 149.2 0.1 1.2e-43 148.2 0.1 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 AEO58314.1 - 4.2e-43 147.0 0.0 6.6e-43 146.4 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 AEO58314.1 - 1.5e-06 27.0 0.0 2.5e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 AEO58314.1 - 0.024 14.9 1.2 0.078 13.2 0.1 2.3 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 AEO58314.1 - 0.056 13.4 0.5 0.15 12.0 0.3 1.7 1 1 0 1 1 1 0 NADH(P)-binding Hydrolase PF00702.21 AEO58315.1 - 7.8e-23 82.0 0.0 4.5e-22 79.5 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 AEO58315.1 - 1.6e-21 76.3 0.0 5e-21 74.7 0.0 1.8 1 1 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 AEO58315.1 - 2.5e-19 70.2 0.0 6e-19 68.9 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AEO58315.1 - 9.4e-05 22.2 0.3 0.00027 20.8 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 AEO58315.1 - 0.0021 17.6 0.1 0.03 13.9 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 AEO58315.1 - 0.0047 16.2 0.4 1.7 7.8 0.0 3.1 3 0 0 3 3 3 1 Sucrose-6F-phosphate phosphohydrolase Aldo_ket_red PF00248.16 AEO58316.1 - 2.3e-78 262.8 0.0 2.6e-78 262.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Sel1 PF08238.7 AEO58316.1 - 0.027 15.1 0.1 1.3 9.7 0.0 3.4 4 0 0 4 4 4 0 Sel1 repeat ketoacyl-synt PF00109.21 AEO58317.1 - 1.9e-75 253.6 0.4 5.1e-75 252.2 0.1 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 AEO58317.1 - 2.1e-47 161.1 0.3 5.6e-46 156.4 0.1 2.6 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.16 AEO58317.1 - 1.2e-45 156.2 0.0 2.5e-45 155.2 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 AEO58317.1 - 1.1e-44 152.2 0.3 3.6e-40 137.6 0.0 3.0 2 0 0 2 2 2 2 short chain dehydrogenase PS-DH PF14765.1 AEO58317.1 - 2.3e-37 128.7 0.1 3.8e-37 128.0 0.1 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase NAD_binding_4 PF07993.7 AEO58317.1 - 1.2e-32 112.8 0.0 2e-32 112.0 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.7 AEO58317.1 - 2.1e-18 66.6 0.0 9.6e-18 64.4 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Ketoacyl-synt_C PF02801.17 AEO58317.1 - 1.4e-17 63.6 5.9 7.4e-16 58.0 0.7 4.0 3 1 0 3 3 2 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_23 PF13489.1 AEO58317.1 - 1.8e-13 50.5 0.0 5.9e-13 48.8 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Epimerase PF01370.16 AEO58317.1 - 7.7e-12 45.1 0.0 3.5e-09 36.4 0.0 2.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_11 PF08241.7 AEO58317.1 - 7.3e-11 42.4 0.4 8.2e-10 39.0 0.0 3.0 4 0 0 4 4 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO58317.1 - 1.4e-07 32.0 0.0 1.1e-06 29.1 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO58317.1 - 5.6e-07 29.2 0.0 1.3e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 AEO58317.1 - 2.5e-05 23.3 0.0 5.5e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.13 AEO58317.1 - 0.00027 20.1 0.0 0.00052 19.1 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family 3Beta_HSD PF01073.14 AEO58317.1 - 0.0014 17.4 0.0 0.039 12.6 0.0 2.3 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NodS PF05401.6 AEO58317.1 - 0.011 15.1 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) PP-binding PF00550.20 AEO58317.1 - 0.011 15.9 0.3 0.033 14.4 0.2 1.8 1 0 0 1 1 1 0 Phosphopantetheine attachment site Semialdhyde_dh PF01118.19 AEO58317.1 - 0.039 14.2 0.2 1.5 9.1 0.0 2.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Methyltransf_28 PF02636.12 AEO58317.1 - 0.053 12.9 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase NNMT_PNMT_TEMT PF01234.12 AEO58317.1 - 0.2 10.5 0.0 1.6 7.6 0.0 2.2 1 1 1 2 2 2 0 NNMT/PNMT/TEMT family RrnaAD PF00398.15 AEO58317.1 - 0.4 9.6 0.0 0.73 8.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase ADH_zinc_N PF00107.21 AEO58318.1 - 3.7e-07 29.7 0.0 8.5e-07 28.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AEO58318.1 - 3.5e-06 26.7 0.0 0.0004 20.1 0.0 3.1 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain 3-alpha PF03475.9 AEO58318.1 - 0.1 12.3 0.0 0.27 10.9 0.1 1.7 2 0 0 2 2 2 0 3-alpha domain p450 PF00067.17 AEO58319.1 - 7.1e-64 216.0 0.0 8.7e-64 215.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.18 AEO58320.1 - 7.9e-16 57.7 2.6 1.6e-15 56.8 1.8 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 AEO58320.1 - 1.7e-07 31.0 1.4 5.7e-07 29.3 0.9 1.9 1 0 0 1 1 1 1 Berberine and berberine like Phage_CRI PF05144.9 AEO58320.1 - 0.2 10.7 0.0 0.3 10.1 0.0 1.2 1 0 0 1 1 1 0 Phage replication protein CRI p450 PF00067.17 AEO58321.1 - 1.1e-25 90.0 0.0 3e-22 78.7 0.0 2.3 2 0 0 2 2 2 2 Cytochrome P450 Fungal_trans PF04082.13 AEO58323.1 - 1.5e-06 27.3 0.0 2.9e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO58323.1 - 1.1e-05 25.2 10.4 2e-05 24.3 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Patatin PF01734.17 AEO58323.1 - 0.032 14.1 1.2 0.079 12.8 0.7 1.6 1 1 0 1 1 1 0 Patatin-like phospholipase SSP160 PF06933.6 AEO58323.1 - 0.95 7.3 13.7 0.082 10.8 2.0 2.1 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 ABM PF03992.11 AEO58324.1 - 2.3e-06 27.5 0.0 2.6e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase adh_short PF00106.20 AEO58325.1 - 4e-14 52.8 0.0 5.9e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO58325.1 - 4.4e-06 26.4 0.0 6.7e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 AEO58325.1 - 4e-05 23.4 0.0 5e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 AEO58325.1 - 0.0013 18.1 0.0 0.0034 16.8 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 AEO58325.1 - 0.025 14.5 0.1 0.054 13.5 0.1 1.5 1 1 0 1 1 1 0 NADH(P)-binding Shikimate_DH PF01488.15 AEO58325.1 - 0.072 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.14 AEO58325.1 - 0.079 12.0 0.0 0.18 10.8 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SOG2 PF10428.4 AEO58326.1 - 0.13 10.9 14.1 0.21 10.2 9.8 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Nucleoplasmin PF03066.10 AEO58326.1 - 0.21 11.1 2.8 0.35 10.3 1.9 1.2 1 0 0 1 1 1 0 Nucleoplasmin Daxx PF03344.10 AEO58326.1 - 0.38 9.1 9.1 1.8 6.9 6.3 1.8 1 1 0 1 1 1 0 Daxx Family Whi5 PF08528.6 AEO58327.1 - 5e-10 38.7 0.0 9.1e-10 37.8 0.0 1.4 1 0 0 1 1 1 1 Whi5 like AA_permease_2 PF13520.1 AEO58328.1 - 3e-81 273.1 30.1 3.6e-81 272.8 20.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 AEO58328.1 - 2.6e-18 65.6 27.6 7.6e-18 64.1 19.1 1.7 1 1 0 1 1 1 1 Amino acid permease Aa_trans PF01490.13 AEO58328.1 - 3.3 6.1 18.5 0.3 9.5 8.5 2.3 2 1 0 2 2 2 0 Transmembrane amino acid transporter protein V-SNARE_C PF12352.3 AEO58329.1 - 1.8e-15 56.7 1.5 3.4e-15 55.8 0.4 1.9 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 AEO58329.1 - 4.5e-05 23.0 0.0 0.0001 21.9 0.0 1.5 1 0 0 1 1 1 1 Sec20 Sigma70_r4 PF04545.11 AEO58329.1 - 0.013 14.7 0.0 0.031 13.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 LIP PF03583.9 AEO58329.1 - 0.03 13.5 0.1 0.045 12.9 0.1 1.2 1 0 0 1 1 1 0 Secretory lipase DivIC PF04977.10 AEO58329.1 - 0.052 13.0 1.4 0.5 9.8 0.0 2.5 2 0 0 2 2 2 0 Septum formation initiator TPK_B1_binding PF04265.9 AEO58330.1 - 1.1e-25 89.0 0.1 1.7e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain TPK_catalytic PF04263.11 AEO58330.1 - 9.4e-19 67.2 0.0 1.5e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain CHCH PF06747.8 AEO58332.1 - 8.2e-07 28.7 6.0 1.4e-06 28.0 4.1 1.4 1 0 0 1 1 1 1 CHCH domain GCK PF07802.6 AEO58332.1 - 0.087 12.9 2.8 0.24 11.5 1.9 1.8 1 0 0 1 1 1 0 GCK domain DUF4139 PF13598.1 AEO58333.1 - 0.077 12.2 3.8 0.085 12.1 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4139) zf-CCHC_4 PF14392.1 AEO58336.1 - 3.1 7.5 8.2 5.4 6.7 5.7 1.4 1 0 0 1 1 1 0 Zinc knuckle Myb_DNA-bind_3 PF12776.2 AEO58337.1 - 3.1e-20 72.5 0.7 3.1e-20 72.5 0.5 2.6 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain PAT1 PF09770.4 AEO58337.1 - 0.00055 18.3 41.1 0.00076 17.8 28.5 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 AEO58337.1 - 0.15 11.8 32.1 0.23 11.3 22.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med15 PF09606.5 AEO58337.1 - 1.4 7.0 50.8 2.2 6.3 35.2 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF1917 PF08939.5 AEO58337.1 - 1.5 8.5 12.5 3.2 7.4 8.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1917) FimP PF09766.4 AEO58337.1 - 1.8 7.5 20.9 1.7 7.6 9.6 2.2 2 0 0 2 2 2 0 Fms-interacting protein DUF4557 PF15101.1 AEO58337.1 - 2.2 8.0 19.2 0.45 10.3 7.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Ufd2P_core PF10408.4 AEO58337.1 - 2.8 6.0 9.8 0.28 9.3 3.4 1.8 3 0 0 3 3 3 0 Ubiquitin elongating factor core Asp PF00026.18 AEO58338.1 - 9.1e-57 192.6 3.0 1.1e-56 192.4 2.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 AEO58338.1 - 2.3e-07 30.8 0.0 2.3e-06 27.6 0.0 2.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 AEO58338.1 - 6.8e-07 29.7 4.8 0.0027 18.1 0.1 3.0 3 1 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.1 AEO58338.1 - 0.0055 16.5 0.3 0.48 10.2 0.0 2.6 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease DDE_1 PF03184.14 AEO58339.1 - 0.00026 20.1 0.0 0.00026 20.1 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 AEO58340.1 - 0.0015 17.7 0.0 0.0017 17.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1825 PF08855.5 AEO58340.1 - 0.13 12.2 0.0 0.16 11.9 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1825) Glyco_hydro_3 PF00933.16 AEO58343.1 - 6e-90 301.2 0.0 8.6e-90 300.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 AEO58343.1 - 4.1e-60 203.1 0.4 7.4e-60 202.2 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 AEO58343.1 - 4.6e-25 87.3 0.0 9.2e-25 86.3 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Zn_clus PF00172.13 AEO58344.1 - 4.5e-08 32.8 29.9 0.00024 20.9 6.5 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4206 PF13901.1 AEO58344.1 - 4.3 6.8 10.5 9.1 5.7 7.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4206) Dickkopf_N PF04706.7 AEO58344.1 - 6.1 7.0 26.7 5.1 7.3 6.6 2.8 2 1 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region Glyco_hydro_3 PF00933.16 AEO58346.1 - 3.4e-60 203.5 0.0 5e-60 203.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 AEO58346.1 - 6.5e-43 146.8 0.0 9.5e-43 146.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 AEO58346.1 - 4.1e-08 33.0 0.0 1.1e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain Aminotran_5 PF00266.14 AEO58347.1 - 4.6e-18 65.1 0.0 2.3e-17 62.7 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V AAA_33 PF13671.1 AEO58348.1 - 0.0044 16.9 0.7 0.0078 16.0 0.5 1.6 1 1 0 1 1 1 1 AAA domain SKI PF01202.17 AEO58348.1 - 0.037 13.8 0.0 0.066 13.0 0.0 1.5 1 1 0 1 1 1 0 Shikimate kinase DNA_pol_B_thumb PF14791.1 AEO58348.1 - 0.14 11.8 0.3 0.26 11.0 0.2 1.5 1 1 0 1 1 1 0 DNA polymerase beta thumb RhoGAP PF00620.22 AEO58349.1 - 5.8e-14 51.9 0.0 8.7e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain Epimerase PF01370.16 AEO58350.1 - 1.3e-20 73.8 0.0 1.7e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 AEO58350.1 - 2.3e-11 42.9 0.0 2.9e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 AEO58350.1 - 2.5e-10 39.7 0.0 8.1e-10 38.0 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 AEO58350.1 - 1.1e-07 32.0 0.0 4.5e-07 30.0 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 AEO58350.1 - 2e-07 31.1 0.0 3.6e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 AEO58350.1 - 4.7e-06 25.7 0.0 4.8e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.5 AEO58350.1 - 2.4e-05 24.0 0.0 4.2e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 AEO58350.1 - 0.0003 20.1 0.0 0.0022 17.2 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family Saccharop_dh PF03435.13 AEO58350.1 - 0.0011 17.9 0.0 0.002 17.1 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 AEO58350.1 - 0.035 14.2 0.0 0.07 13.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short_C2 PF13561.1 AEO58350.1 - 0.039 13.7 0.0 0.064 13.0 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase FAD_binding_3 PF01494.14 AEO58351.1 - 6.4e-16 58.3 8.8 4.8e-11 42.3 2.2 3.0 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 AEO58351.1 - 2e-07 30.2 1.7 1.1e-05 24.5 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 AEO58351.1 - 0.00023 20.9 0.0 0.00062 19.5 0.0 1.8 1 0 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 AEO58351.1 - 0.00078 19.4 1.7 0.00078 19.4 1.2 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 AEO58351.1 - 0.00096 19.5 0.1 0.0021 18.4 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 AEO58351.1 - 0.003 17.4 0.1 0.0053 16.6 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AEO58351.1 - 0.018 15.1 0.2 0.041 13.9 0.1 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 AEO58351.1 - 0.03 13.1 1.6 0.046 12.5 1.1 1.2 1 0 0 1 1 1 0 FAD binding domain His_Phos_2 PF00328.17 AEO58353.1 - 5.4e-13 48.9 0.0 1.2e-11 44.5 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) O-antigen_lig PF13425.1 AEO58353.1 - 0.099 12.6 0.3 0.27 11.2 0.2 1.7 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Fungal_trans PF04082.13 AEO58354.1 - 4.1e-18 65.1 0.0 5.6e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO58354.1 - 2e-09 37.1 14.0 3e-09 36.6 9.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Serglycin PF04360.7 AEO58354.1 - 0.11 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Serglycin YL1_C PF08265.6 AEO58354.1 - 0.15 11.6 0.3 0.44 10.1 0.2 1.8 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain adh_short PF00106.20 AEO58355.1 - 6.6e-18 65.1 0.5 9.6e-18 64.6 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO58355.1 - 3.8e-09 36.6 0.0 5.1e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO58355.1 - 1.8e-06 27.7 0.3 3.1e-06 26.9 0.2 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 AEO58355.1 - 2.2e-06 27.2 0.0 2.5e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 AEO58355.1 - 0.04 13.9 1.5 0.096 12.6 0.4 2.1 2 1 1 3 3 3 0 NADH(P)-binding ketoacyl-synt PF00109.21 AEO58356.1 - 3.2e-72 243.0 0.0 1.1e-71 241.3 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 AEO58356.1 - 6.9e-55 186.5 0.1 1.3e-54 185.7 0.1 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 AEO58356.1 - 2.4e-33 114.4 1.6 9.1e-33 112.6 1.1 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 AEO58356.1 - 3.4e-10 40.0 0.6 9.2e-10 38.6 0.1 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 AEO58356.1 - 1.4e-05 24.2 0.0 3e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_5 PF12695.2 AEO58356.1 - 0.00062 19.5 0.8 0.0032 17.2 0.2 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family Lactamase_B PF00753.22 AEO58357.1 - 2.7e-22 79.3 3.0 3.6e-22 78.9 2.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 AEO58357.1 - 9.7e-07 28.5 1.4 1.5e-06 27.8 0.9 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF1772 PF08592.6 AEO58358.1 - 6.3e-26 90.7 3.3 7.6e-26 90.5 2.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) DUF3633 PF12315.3 AEO58358.1 - 0.019 14.2 0.0 0.025 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3633) DUF4234 PF14018.1 AEO58358.1 - 0.052 13.2 0.0 0.087 12.5 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4234) EthD PF07110.6 AEO58359.1 - 3.5e-21 75.9 0.2 4.7e-21 75.5 0.2 1.2 1 0 0 1 1 1 1 EthD domain AflR PF08493.5 AEO58360.1 - 1.8e-14 53.4 4.3 1.8e-14 53.4 3.0 3.0 2 1 1 3 3 3 1 Aflatoxin regulatory protein Zn_clus PF00172.13 AEO58360.1 - 2.1e-07 30.7 8.7 4.4e-07 29.6 6.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain API5 PF05918.6 AEO58360.1 - 0.028 12.9 0.5 0.042 12.3 0.4 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF456 PF04306.8 AEO58360.1 - 0.26 11.3 0.6 0.55 10.2 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF456) NAD_binding_10 PF13460.1 AEO58361.1 - 9.3e-14 51.8 0.0 1.2e-13 51.4 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 AEO58361.1 - 5.6e-07 29.0 0.0 2.2e-06 27.1 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.14 AEO58361.1 - 0.004 15.8 0.0 0.0068 15.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 AEO58361.1 - 0.0086 16.3 0.0 0.015 15.6 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 AEO58361.1 - 0.015 14.7 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DXP_reductoisom PF02670.11 AEO58361.1 - 0.086 13.3 0.0 0.16 12.4 0.0 1.6 1 1 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase NAD_binding_4 PF07993.7 AEO58361.1 - 0.11 11.3 0.0 0.28 10.0 0.0 1.7 1 1 0 1 1 1 0 Male sterility protein p450 PF00067.17 AEO58362.1 - 2.3e-58 197.8 0.0 3.1e-58 197.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF4267 PF14087.1 AEO58363.1 - 2.1e-14 53.0 0.4 2.5e-14 52.8 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) DUF3317 PF11779.3 AEO58363.1 - 0.32 10.4 2.0 19 4.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3317) FAD_binding_3 PF01494.14 AEO58364.1 - 5.1e-22 78.4 0.7 1.7e-10 40.4 0.0 2.5 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 AEO58364.1 - 1.9e-05 24.5 0.0 5.1e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 AEO58364.1 - 3.1e-05 23.0 0.1 0.006 15.5 0.0 3.0 2 1 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.19 AEO58364.1 - 0.00066 18.6 0.1 0.33 9.7 0.0 3.0 2 1 0 3 3 3 1 FAD dependent oxidoreductase SE PF08491.5 AEO58364.1 - 0.0034 16.2 0.0 0.022 13.6 0.0 2.0 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox_2 PF07992.9 AEO58364.1 - 0.0034 17.2 0.0 0.022 14.6 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AEO58364.1 - 0.012 15.9 0.0 0.11 12.9 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AEO58364.1 - 0.016 15.2 0.0 0.03 14.3 0.0 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 AEO58364.1 - 0.032 13.9 0.0 0.072 12.8 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Thi4 PF01946.12 AEO58364.1 - 0.033 13.2 0.0 0.052 12.6 0.0 1.2 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.14 AEO58365.1 - 1.7e-12 47.0 0.0 4.1e-12 45.8 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 AEO58365.1 - 2.8e-10 39.6 9.1 1.3e-05 24.2 0.1 3.2 1 1 2 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 AEO58365.1 - 1.1e-05 24.5 1.5 0.0024 16.7 0.3 2.2 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.9 AEO58365.1 - 0.00088 17.8 0.3 0.07 11.5 0.2 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.9 AEO58365.1 - 0.0035 17.2 0.1 0.0063 16.4 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AEO58365.1 - 0.01 15.9 0.4 0.049 13.6 0.3 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AEO58365.1 - 0.027 14.4 0.1 0.093 12.7 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 AEO58365.1 - 0.056 12.5 1.4 0.092 11.7 0.3 1.8 2 1 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 AEO58365.1 - 0.16 12.3 0.3 8.9 6.8 0.2 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NodS PF05401.6 AEO58366.1 - 0.067 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_11 PF08241.7 AEO58367.1 - 2.6e-11 43.8 0.1 4e-11 43.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO58367.1 - 1.4e-08 35.1 0.0 2.1e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO58367.1 - 3.4e-08 34.0 0.1 5.9e-08 33.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO58367.1 - 5.8e-08 32.6 0.0 1.8e-07 31.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO58367.1 - 8.5e-07 28.6 0.0 1.2e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO58367.1 - 2e-06 28.1 0.1 3.9e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AEO58367.1 - 0.00023 20.5 0.0 0.00035 20.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.6 AEO58367.1 - 0.029 13.7 0.0 0.039 13.3 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) CheR PF01739.13 AEO58367.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Scytalone_dh PF02982.9 AEO58368.1 - 6.7e-64 214.2 2.0 7.3e-64 214.1 1.4 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 AEO58368.1 - 2.1e-08 34.1 1.5 2.4e-08 33.9 1.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain adh_short PF00106.20 AEO58369.1 - 1.8e-31 109.2 1.5 2.7e-31 108.7 1.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO58369.1 - 2.5e-26 92.9 0.0 3.1e-26 92.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO58369.1 - 5.1e-13 49.0 0.8 7.2e-13 48.5 0.5 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 AEO58369.1 - 0.018 14.4 0.9 0.037 13.4 0.6 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Methyltransf_11 PF08241.7 AEO58369.1 - 0.032 14.7 0.3 0.19 12.2 0.2 2.3 1 1 0 1 1 1 0 Methyltransferase domain Aminotran_1_2 PF00155.16 AEO58369.1 - 0.056 12.3 0.0 0.08 11.8 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II DUF1776 PF08643.5 AEO58369.1 - 0.081 12.0 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) CPSase_L_chain PF00289.17 AEO58369.1 - 0.12 12.5 0.5 0.36 10.9 0.3 1.8 1 1 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain Methyltransf_18 PF12847.2 AEO58369.1 - 0.13 12.8 0.1 0.28 11.7 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain FAD_binding_4 PF01565.18 AEO58370.1 - 1.2e-20 73.4 1.4 2.5e-20 72.3 1.0 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 AEO58370.1 - 2.1e-12 46.7 1.1 5.8e-12 45.3 0.8 1.8 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 AEO58370.1 - 0.098 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding DUF4243 PF14027.1 AEO58371.1 - 6.9e-83 278.8 0.0 8.4e-83 278.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Peptidase_MA_2 PF13485.1 AEO58371.1 - 0.091 12.8 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 Peptidase MA superfamily SnoaL_2 PF12680.2 AEO58372.1 - 0.12 12.7 0.0 0.19 12.1 0.0 1.4 1 1 0 1 1 1 0 SnoaL-like domain MFS_1 PF07690.11 AEO58373.1 - 2e-36 125.4 3.6 2e-36 125.4 2.5 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Chordopox_G3 PF06129.7 AEO58373.1 - 0.2 11.8 0.2 0.35 11.0 0.2 1.3 1 0 0 1 1 1 0 Chordopoxvirus G3 protein FAD_binding_4 PF01565.18 AEO58374.1 - 1.8e-19 69.5 1.6 3.1e-19 68.8 0.7 1.8 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.7 AEO58374.1 - 7.7e-10 38.5 0.6 1.4e-09 37.6 0.0 1.8 2 0 0 2 2 2 1 Berberine and berberine like TPR_11 PF13414.1 AEO58378.1 - 1.1e-16 60.2 6.5 6.9e-12 44.8 1.3 5.0 4 1 1 5 5 5 2 TPR repeat TPR_1 PF00515.23 AEO58378.1 - 1.3e-12 46.6 6.0 0.00029 20.3 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 AEO58378.1 - 3.5e-12 45.2 14.0 1.8e-05 24.2 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 AEO58378.1 - 2.4e-10 40.8 1.6 2.4e-10 40.8 1.1 4.3 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 AEO58378.1 - 5e-09 35.9 9.3 0.003 17.4 0.1 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 AEO58378.1 - 7.7e-09 34.7 1.8 0.002 17.7 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 AEO58378.1 - 3.3e-07 30.3 2.0 0.0002 21.6 0.2 6.2 6 1 1 7 7 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 AEO58378.1 - 4.1e-06 26.1 2.1 0.0015 18.1 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 AEO58378.1 - 2.4e-05 24.1 2.5 0.14 12.4 0.0 4.4 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 AEO58378.1 - 0.00015 21.9 5.5 0.037 14.3 0.2 3.8 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_21 PF09976.4 AEO58378.1 - 0.00038 20.4 0.3 1.5 8.7 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat SNAP PF14938.1 AEO58378.1 - 0.0037 16.4 0.2 0.0073 15.4 0.2 1.4 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_6 PF13174.1 AEO58378.1 - 0.2 12.2 8.0 7.4 7.2 0.1 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 AEO58378.1 - 0.61 10.0 8.0 0.18 11.7 1.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat GYF PF02213.11 AEO58379.1 - 2.7e-19 68.5 0.1 5.4e-19 67.5 0.0 1.6 1 0 0 1 1 1 1 GYF domain SnoaL PF07366.7 AEO58380.1 - 0.0015 18.1 0.0 0.0027 17.2 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase DLH PF01738.13 AEO58380.1 - 0.019 14.2 0.0 0.032 13.5 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family SnoaL_2 PF12680.2 AEO58380.1 - 0.13 12.6 0.1 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 SnoaL-like domain MTBP_mid PF14919.1 AEO58380.1 - 0.24 10.0 0.0 0.35 9.5 0.0 1.1 1 0 0 1 1 1 0 MDM2-binding Lig_chan PF00060.21 AEO58381.1 - 0.32 10.7 4.7 0.6 9.8 3.3 1.5 1 0 0 1 1 1 0 Ligand-gated ion channel OppC_N PF12911.2 AEO58381.1 - 6.6 6.1 6.1 13 5.2 0.8 2.7 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C 5_nucleotid_C PF02872.13 AEO58382.1 - 2.2e-36 125.1 0.0 6.3e-36 123.7 0.0 1.7 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 AEO58382.1 - 6.5e-08 32.2 0.1 9.9e-08 31.6 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 AEO58382.1 - 0.0021 17.9 0.0 0.0045 16.8 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Acetyltransf_1 PF00583.19 AEO58383.1 - 3.1e-14 52.7 0.1 4.9e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 AEO58383.1 - 7.1e-09 35.3 0.0 1.2e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 AEO58383.1 - 4.5e-06 26.7 0.0 7e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 AEO58383.1 - 2.2e-05 24.5 0.0 2.9e-05 24.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 AEO58383.1 - 0.00045 20.3 0.0 0.0005 20.2 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 AEO58383.1 - 0.077 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF3749 PF12568.3 AEO58383.1 - 0.13 11.8 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Complex1_LYR_1 PF13232.1 AEO58384.1 - 1.2e-07 31.8 0.4 3e-07 30.5 0.3 1.8 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 AEO58384.1 - 1.7e-07 30.8 0.7 4.3e-07 29.6 0.5 1.7 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Ank_4 PF13637.1 AEO58385.1 - 1e-16 60.9 2.8 1.1e-08 35.3 0.1 4.6 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 AEO58385.1 - 1.1e-15 57.7 0.1 1.7e-06 28.2 0.0 3.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 AEO58385.1 - 9.7e-14 50.3 1.0 7.7e-06 25.4 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 AEO58385.1 - 1.6e-13 50.3 0.5 2.6e-05 24.3 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 AEO58385.1 - 1.9e-12 46.1 0.3 0.0003 20.7 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.8 AEO58385.1 - 2.4e-05 23.9 0.3 0.00018 21.0 0.2 2.5 1 1 0 1 1 1 1 KilA-N domain Reo_sigmaC PF04582.7 AEO58385.1 - 1.3 8.1 5.6 0.48 9.5 1.9 1.6 2 0 0 2 2 2 0 Reovirus sigma C capsid protein NAD_binding_7 PF13241.1 AEO58386.1 - 1.5e-34 118.3 0.0 2.2e-34 117.8 0.0 1.2 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 AEO58386.1 - 4.3e-25 86.8 0.0 6.4e-25 86.2 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 AEO58386.1 - 8.6e-14 50.2 0.0 1.3e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central ThiF PF00899.16 AEO58386.1 - 0.0061 16.3 0.9 0.0099 15.7 0.0 1.7 1 1 1 2 2 2 1 ThiF family TrkA_N PF02254.13 AEO58386.1 - 0.022 14.7 0.1 0.037 14.0 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.15 AEO58386.1 - 0.084 12.9 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ELFV_dehydrog PF00208.16 AEO58386.1 - 0.16 11.5 0.1 0.25 10.9 0.1 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase FYVE PF01363.16 AEO58387.1 - 1.1e-19 70.0 26.6 3.8e-15 55.5 5.7 2.9 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.3 AEO58387.1 - 0.0035 16.8 0.7 0.0035 16.8 0.5 2.1 2 0 0 2 2 2 1 Rabenosyn Rab binding domain zf-AN1 PF01428.11 AEO58387.1 - 0.011 15.6 2.4 0.011 15.6 1.6 3.4 5 0 0 5 5 5 0 AN1-like Zinc finger zf-Di19 PF05605.7 AEO58387.1 - 0.024 14.7 10.8 0.058 13.5 0.1 3.1 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 AEO58387.1 - 1.6 9.0 6.4 3.3 8.0 0.2 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type CENP-L PF13092.1 AEO58388.1 - 1.3e-48 164.8 0.0 1.7e-48 164.5 0.0 1.2 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 Pkinase PF00069.20 AEO58389.1 - 9e-17 61.0 0.0 1.2e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO58389.1 - 1.8e-08 33.8 0.0 2.5e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AEO58389.1 - 2e-06 27.7 0.0 3.2e-06 27.0 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 AEO58389.1 - 4e-05 23.0 0.0 9.6e-05 21.8 0.0 1.6 1 1 1 2 2 2 1 RIO1 family Kdo PF06293.9 AEO58389.1 - 5.8e-05 22.2 0.0 8.7e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 AEO58389.1 - 0.0079 15.7 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.1 AEO58389.1 - 0.077 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like p450 PF00067.17 AEO58390.1 - 7.4e-64 215.9 0.0 9.6e-64 215.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Hira PF07569.6 AEO58390.1 - 0.16 11.1 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 TUP1-like enhancer of split Cutinase PF01083.17 AEO58391.1 - 4.9e-49 166.4 10.4 2.8e-48 164.0 7.2 1.8 1 1 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.15 AEO58391.1 - 7.2e-05 22.4 0.1 0.00014 21.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold PE-PPE PF08237.6 AEO58391.1 - 0.0001 21.7 0.1 0.00014 21.3 0.1 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_6 PF12697.2 AEO58391.1 - 0.04 13.7 0.1 0.05 13.4 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family VirJ PF06057.6 AEO58391.1 - 0.048 13.4 0.0 0.074 12.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DUF4360 PF14273.1 AEO58392.1 - 3.3e-57 193.1 0.6 3.8e-57 192.9 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) ADP_ribosyl_GH PF03747.9 AEO58393.1 - 3.9e-32 112.1 0.4 4.3e-32 112.0 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Sulfate_transp PF00916.15 AEO58394.1 - 4.5e-50 170.2 2.2 5.3e-50 169.9 0.5 1.7 1 1 1 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 AEO58394.1 - 5.8e-27 93.1 4.0 5.8e-27 93.1 2.7 2.5 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 AEO58394.1 - 7.9e-17 60.7 0.0 1.5e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 AEO58394.1 - 0.0059 16.6 0.0 0.018 15.0 0.0 1.9 1 0 0 1 1 1 1 STAS domain DUF3636 PF12331.3 AEO58395.1 - 1.4e-44 151.2 0.0 2.6e-44 150.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) Atg14 PF10186.4 AEO58395.1 - 3.3 6.5 6.1 6.9 5.5 4.2 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 PAT1 PF09770.4 AEO58395.1 - 4.9 5.2 28.1 7.6 4.6 19.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CTP_transf_1 PF01148.15 AEO58396.1 - 1.2e-78 264.4 28.6 1.5e-78 264.0 19.8 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family TCR_zetazeta PF11628.3 AEO58396.1 - 0.022 14.2 1.1 0.085 12.3 0.8 2.0 1 0 0 1 1 1 0 T-cell surface glycoprotein CD3 zeta chain Thiolase_N PF00108.18 AEO58397.1 - 2.4e-71 239.8 0.2 3.7e-71 239.1 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 AEO58397.1 - 6e-40 135.4 0.4 1.4e-39 134.3 0.2 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 AEO58397.1 - 0.027 14.1 0.1 0.91 9.2 0.0 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Glyco_hydro_cc PF11790.3 AEO58398.1 - 5.8e-70 235.4 0.5 6.8e-70 235.1 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_43 PF04616.9 AEO58399.1 - 2.5e-106 354.9 1.0 4.3e-106 354.1 0.7 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DRY_EERY PF09750.4 AEO58400.1 - 0.063 13.3 0.1 0.12 12.4 0.0 1.5 2 0 0 2 2 2 0 Alternative splicing regulator GMC_oxred_N PF00732.14 AEO58401.1 - 1.6e-48 165.3 0.0 3.2e-48 164.3 0.0 1.5 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 AEO58401.1 - 1.1e-29 103.6 0.0 2e-29 102.7 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 AEO58401.1 - 1.2e-11 44.1 0.1 3.2e-06 26.2 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 AEO58401.1 - 2.9e-05 23.0 0.0 0.0012 17.7 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 AEO58401.1 - 5.9e-05 23.0 0.1 0.00017 21.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 AEO58401.1 - 0.0028 16.1 0.0 0.038 12.4 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 AEO58401.1 - 0.011 15.5 0.1 0.51 10.1 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 AEO58401.1 - 0.019 14.7 0.1 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 AEO58401.1 - 0.02 14.9 0.2 0.3 11.1 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 AEO58401.1 - 0.022 13.8 0.0 0.039 13.0 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 AEO58401.1 - 0.11 11.4 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein TrkA_N PF02254.13 AEO58401.1 - 0.14 12.1 0.5 0.33 10.9 0.1 1.8 2 0 0 2 2 2 0 TrkA-N domain p450 PF00067.17 AEO58402.1 - 3.2e-77 260.0 0.0 4.4e-77 259.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 AEO58402.1 - 7.6e-33 113.7 0.0 1.2e-32 113.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 AEO58402.1 - 1.3e-22 80.3 0.0 3.9e-22 78.7 0.0 1.8 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.16 AEO58402.1 - 1.3e-13 51.4 0.0 5.9e-13 49.3 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 AEO58402.1 - 0.047 13.7 0.0 0.12 12.3 0.0 1.7 2 0 0 2 2 2 0 Flavodoxin domain Zn_clus PF00172.13 AEO58403.1 - 0.00043 20.1 10.9 0.00095 19.0 7.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3425 PF11905.3 AEO58404.1 - 7.1e-23 81.0 0.3 1.2e-22 80.3 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) DUF1996 PF09362.5 AEO58405.1 - 5e-85 284.9 0.5 6e-85 284.6 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) NmrA PF05368.8 AEO58408.1 - 2.2e-12 46.7 0.0 2.6e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 AEO58408.1 - 1.5e-08 34.8 0.0 2.5e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding E1-N PF14463.1 AEO58408.1 - 0.023 14.2 0.2 0.042 13.4 0.1 1.4 1 0 0 1 1 1 0 E1 N-terminal domain KR PF08659.5 AEO58408.1 - 0.058 13.0 0.0 8.5 6.0 0.0 3.2 2 1 0 2 2 2 0 KR domain GMC_oxred_C PF05199.8 AEO58409.1 - 3.3e-23 82.5 0.0 5.7e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 AEO58409.1 - 2e-22 79.6 0.0 3e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase Glyoxalase_2 PF12681.2 AEO58410.1 - 2.4e-05 24.8 2.2 0.016 15.7 0.2 2.8 2 1 1 3 3 3 2 Glyoxalase-like domain Glyoxalase PF00903.20 AEO58410.1 - 2.5e-05 24.2 1.4 0.011 15.7 0.2 3.3 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 AEO58410.1 - 0.0061 16.5 0.0 1.1 9.3 0.0 2.6 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FAD_binding_3 PF01494.14 AEO58411.1 - 9e-28 97.3 0.0 1.3e-27 96.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Glyco_hydro_61 PF03443.9 AEO58412.1 - 1.5e-55 188.4 0.0 4.9e-30 104.9 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 61 ATP-synt_C PF00137.16 AEO58413.1 - 2e-26 91.6 26.3 1.3e-16 60.2 7.9 2.1 2 0 0 2 2 2 2 ATP synthase subunit C ABA_GPCR PF12430.3 AEO58413.1 - 0.045 12.8 2.6 2 7.5 0.1 2.2 2 0 0 2 2 2 0 Abscisic acid G-protein coupled receptor MFS_1 PF07690.11 AEO58414.1 - 5.3e-27 94.4 20.5 1.7e-26 92.7 14.9 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF423 PF04241.10 AEO58414.1 - 0.2 11.5 5.9 1.3 8.9 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF423) DUF607 PF04678.8 AEO58415.1 - 5.8e-38 130.6 0.8 5.8e-38 130.6 0.6 2.8 2 1 0 2 2 2 1 Protein of unknown function, DUF607 tRNA_bind_2 PF13725.1 AEO58415.1 - 0.11 12.6 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 Possible tRNA binding domain Acetyltransf_8 PF13523.1 AEO58416.1 - 1.2e-36 125.8 0.1 2e-36 125.1 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain adh_short PF00106.20 AEO58418.1 - 3.4e-16 59.6 0.9 6.3e-16 58.7 0.1 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 AEO58418.1 - 6.9e-05 22.5 0.1 0.00012 21.8 0.1 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 AEO58418.1 - 0.079 11.8 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Sugar_tr PF00083.19 AEO58419.1 - 6.4e-115 384.2 24.5 7.5e-115 384.0 17.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO58419.1 - 2.8e-32 111.7 30.9 3.2e-30 105.0 18.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 AEO58419.1 - 3e-09 35.7 18.3 9.2e-06 24.3 0.4 3.4 3 0 0 3 3 3 3 MFS/sugar transport protein MFS_1_like PF12832.2 AEO58419.1 - 0.0018 18.0 0.1 0.034 13.9 0.0 3.1 2 0 0 2 2 2 1 MFS_1 like family DUF3040 PF11239.3 AEO58419.1 - 0.62 10.1 5.0 16 5.6 0.1 4.1 3 1 0 3 3 3 0 Protein of unknown function (DUF3040) PNK3P PF08645.6 AEO58420.1 - 5e-56 188.5 0.0 7.9e-56 187.8 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 AEO58420.1 - 2.1e-28 99.0 0.0 1.3e-27 96.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 AEO58420.1 - 0.0091 16.1 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 AEO58420.1 - 0.01 14.9 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.1 AEO58420.1 - 0.017 14.6 0.0 0.052 13.0 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 AEO58420.1 - 0.021 15.6 0.0 0.067 14.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 AEO58420.1 - 0.051 12.9 0.0 1.2 8.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 AEO58420.1 - 0.055 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain HAD_2 PF13419.1 AEO58420.1 - 0.062 13.5 0.2 12 6.0 0.0 3.1 2 1 1 3 3 3 0 Haloacid dehalogenase-like hydrolase DUF258 PF03193.11 AEO58420.1 - 0.089 11.9 0.0 0.19 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 AEO58420.1 - 0.17 12.2 0.4 11 6.3 0.1 2.4 1 1 1 2 2 2 0 AAA domain Nucleos_tra2_C PF07662.8 AEO58421.1 - 9.7e-67 224.4 0.6 9.7e-67 224.4 0.4 2.4 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 AEO58421.1 - 3.1e-21 75.5 4.3 4.3e-21 75.0 0.8 2.9 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.9 AEO58421.1 - 0.18 11.7 17.9 0.017 15.0 6.3 3.4 2 1 1 3 3 3 0 Nucleoside recognition Glyco_hydro_43 PF04616.9 AEO58422.1 - 2.5e-34 118.6 1.5 3e-34 118.4 1.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_43 PF04616.9 AEO58423.1 - 1.4e-47 162.1 5.8 1.6e-47 161.9 4.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Hemerythrin PF01814.18 AEO58424.1 - 8.5e-09 35.6 0.3 1.6e-08 34.8 0.1 1.5 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain ILVD_EDD PF00920.16 AEO58425.1 - 3.6e-18 65.2 0.0 4.6e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Dehydratase family MDM31_MDM32 PF08118.6 AEO58425.1 - 0.056 11.9 0.0 0.069 11.5 0.0 1.1 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins ILVD_EDD PF00920.16 AEO58426.1 - 3.4e-98 329.3 0.3 5.1e-98 328.7 0.2 1.2 1 1 0 1 1 1 1 Dehydratase family DUF3530 PF12048.3 AEO58426.1 - 0.016 14.2 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) MARVEL PF01284.18 AEO58428.1 - 8.2e-10 38.6 20.9 1.2e-09 38.1 14.5 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF2638 PF10937.3 AEO58429.1 - 5.1e-37 127.3 0.8 6e-37 127.1 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) APH PF01636.18 AEO58430.1 - 7.7e-10 38.9 0.9 1.3e-06 28.3 0.1 2.2 1 1 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 AEO58430.1 - 1.4e-06 28.0 0.0 2.2e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 AEO58430.1 - 0.012 14.9 0.2 0.78 9.0 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Pkinase PF00069.20 AEO58430.1 - 0.09 11.9 0.0 2 7.5 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain Cyto_heme_lyase PF01265.12 AEO58431.1 - 2.4e-87 292.8 0.0 2.9e-87 292.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase DUF647 PF04884.9 AEO58432.1 - 2.6e-100 334.7 1.0 3.7e-100 334.2 0.7 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis GHMP_kinases_N PF00288.21 AEO58433.1 - 2.7e-10 40.1 3.5 8.3e-10 38.5 1.2 2.4 2 0 0 2 2 2 1 GHMP kinases N terminal domain E1-E2_ATPase PF00122.15 AEO58434.1 - 3.1e-65 219.4 5.1 7.2e-65 218.2 3.5 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 AEO58434.1 - 2.7e-29 102.0 4.8 3.2e-29 101.7 0.0 3.0 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 AEO58434.1 - 2.6e-27 96.6 0.0 6.3e-26 92.1 0.0 2.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 AEO58434.1 - 5.2e-16 57.8 0.0 1.4e-15 56.4 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 AEO58434.1 - 9.3e-13 48.7 0.3 4.1e-12 46.6 0.2 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AEO58434.1 - 9.9e-12 44.6 0.0 2.3e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 AEO58434.1 - 1.6e-05 24.6 3.5 8.1e-05 22.3 0.7 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hemerythrin PF01814.18 AEO58435.1 - 3.5e-05 23.9 0.4 6.1e-05 23.1 0.3 1.4 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain OPT PF03169.10 AEO58436.1 - 3e-09 35.8 1.6 3.8e-09 35.5 1.1 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein BNR_2 PF13088.1 AEO58437.1 - 1.8e-11 43.8 0.1 4.4e-08 32.7 0.0 3.4 1 1 1 3 3 3 3 BNR repeat-like domain BNR PF02012.15 AEO58437.1 - 9.8e-05 21.6 6.8 0.18 11.7 0.8 3.5 3 0 0 3 3 3 2 BNR/Asp-box repeat Glyco_hydro_76 PF03663.9 AEO58439.1 - 5.6e-145 483.3 0.1 7e-145 483.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Gcd10p PF04189.8 AEO58440.1 - 1.1e-65 221.6 0.0 1.8e-65 221.0 0.0 1.2 1 0 0 1 1 1 1 Gcd10p family P21-Arc PF04062.9 AEO58441.1 - 9.1e-79 263.2 0.0 1e-78 263.0 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit DUF1974 PF09317.6 AEO58441.1 - 0.064 12.6 0.1 0.13 11.6 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1974) COesterase PF00135.23 AEO58443.1 - 2.5e-98 330.1 0.0 3.3e-98 329.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 AEO58443.1 - 0.0029 17.2 0.5 0.0076 15.8 0.3 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 AEO58443.1 - 0.2 10.8 0.6 0.36 10.0 0.4 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Pro-kuma_activ PF09286.6 AEO58444.1 - 8.6e-45 152.2 0.0 1.8e-44 151.2 0.0 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 AEO58444.1 - 2.7e-05 23.4 0.0 5e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Subtilase family Alpha-amylase PF00128.19 AEO58445.1 - 1.5e-22 80.4 0.0 1.1e-19 70.9 0.0 2.5 2 1 0 2 2 2 2 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 AEO58445.1 - 3.6e-16 59.4 0.0 5.9e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 AEO58445.1 - 3.8e-08 32.9 0.0 8.2e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 AEO58445.1 - 1.6e-06 28.3 0.0 4.7e-06 26.7 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3793 PF12672.2 AEO58445.1 - 0.57 9.7 0.0 1.4 8.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3793) Alpha-amylase PF00128.19 AEO58446.1 - 1e-60 205.8 0.3 1.4e-60 205.3 0.2 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 AEO58446.1 - 6.7e-28 96.6 0.3 1.4e-27 95.6 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) FAD_binding_2 PF00890.19 AEO58447.1 - 4.1e-92 309.2 0.2 4.6e-92 309.0 0.1 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 AEO58447.1 - 4.9e-06 26.4 0.1 2.4e-05 24.2 0.0 2.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 AEO58447.1 - 9.4e-06 25.6 0.0 0.00027 20.8 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 AEO58447.1 - 4.8e-05 22.5 0.0 8.6e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 AEO58447.1 - 0.00012 21.2 0.0 0.00029 20.0 0.0 1.6 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 AEO58447.1 - 0.00012 21.0 0.1 0.00012 21.0 0.1 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A DAO PF01266.19 AEO58447.1 - 0.00021 20.2 0.7 0.0018 17.2 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 AEO58447.1 - 0.00044 20.0 0.0 0.00085 19.1 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 AEO58447.1 - 0.00063 19.8 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 AEO58447.1 - 0.0019 16.7 2.8 0.011 14.2 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 AEO58447.1 - 0.0027 16.8 0.0 0.0047 16.0 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 AEO58447.1 - 0.02 13.8 0.3 0.039 12.8 0.2 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein GMC_oxred_N PF00732.14 AEO58447.1 - 0.11 11.6 0.1 0.56 9.2 0.0 2.0 2 0 0 2 2 2 0 GMC oxidoreductase Oxysterol_BP PF01237.13 AEO58449.1 - 2.4e-57 194.0 0.0 1.5e-47 161.8 0.0 2.9 2 1 0 2 2 2 2 Oxysterol-binding protein Nucleoplasmin PF03066.10 AEO58449.1 - 0.0041 16.6 7.4 0.0093 15.4 5.2 1.5 1 0 0 1 1 1 1 Nucleoplasmin Zip PF02535.17 AEO58449.1 - 0.0062 15.5 0.1 0.015 14.3 0.0 1.5 1 1 0 1 1 1 1 ZIP Zinc transporter RNase_H2_suC PF08615.6 AEO58449.1 - 0.12 12.1 5.1 0.49 10.2 3.4 1.9 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) CobT PF06213.7 AEO58449.1 - 0.8 8.7 10.2 1.9 7.5 7.1 1.6 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT HSP90 PF00183.13 AEO58449.1 - 3.3 5.9 13.6 5.2 5.3 9.4 1.2 1 0 0 1 1 1 0 Hsp90 protein PBP1_TM PF14812.1 AEO58449.1 - 4 7.8 16.3 2 8.8 9.0 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Paf1 PF03985.8 AEO58449.1 - 6.1 5.4 13.0 5.8 5.5 8.0 1.5 2 0 0 2 2 2 0 Paf1 Nop14 PF04147.7 AEO58449.1 - 6.9 4.4 13.5 0.59 7.9 5.9 1.6 2 0 0 2 2 2 0 Nop14-like family Tom37_C PF11801.3 AEO58449.1 - 9.6 6.0 6.7 20 5.0 3.5 2.0 2 0 0 2 2 2 0 Tom37 C-terminal domain Secretin_N_2 PF07655.8 AEO58449.1 - 9.9 6.6 9.1 37 4.7 2.3 2.4 2 0 0 2 2 2 0 Secretin N-terminal domain FAD-oxidase_C PF02913.14 AEO58450.1 - 2.3e-35 122.1 0.1 2.7e-35 121.8 0.1 1.0 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain Sugar_tr PF00083.19 AEO58451.1 - 5.8e-99 331.7 17.1 6.6e-99 331.5 11.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO58451.1 - 1.5e-28 99.5 27.8 9.8e-21 73.8 7.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Alpha-L-AF_C PF06964.7 AEO58452.1 - 8.8e-34 116.8 0.0 1.6e-33 115.9 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus Sugar_tr PF00083.19 AEO58453.1 - 6.5e-100 334.8 33.5 8.8e-100 334.3 23.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO58453.1 - 5.7e-22 77.9 36.9 6.6e-20 71.1 15.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Cellulase PF00150.13 AEO58455.1 - 6e-53 179.8 2.4 7.3e-53 179.5 1.7 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Tcp11 PF05794.8 AEO58459.1 - 6e-43 147.1 0.1 1.3e-42 146.0 0.0 1.5 2 0 0 2 2 2 1 T-complex protein 11 Peptidase_M1 PF01433.15 AEO58460.1 - 9.2e-130 433.2 0.1 1.6e-129 432.4 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 AEO58460.1 - 2.6e-69 233.9 0.1 5.3e-69 232.9 0.1 1.5 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 AEO58460.1 - 4.4e-21 75.2 1.1 1e-19 70.8 0.0 2.6 1 1 1 2 2 2 1 Peptidase MA superfamily DUF45 PF01863.12 AEO58460.1 - 0.0017 18.1 0.1 0.0054 16.5 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function DUF45 SprT-like PF10263.4 AEO58460.1 - 0.13 11.8 0.1 0.37 10.4 0.0 1.7 2 0 0 2 2 2 0 SprT-like family DUF1479 PF07350.7 AEO58461.1 - 3.6e-164 546.2 0.0 4.2e-164 545.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) MFS_1 PF07690.11 AEO58463.1 - 4e-27 94.8 55.9 4.3e-24 84.8 18.0 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO58463.1 - 0.0011 17.6 5.2 0.0011 17.6 3.6 2.2 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 AEO58463.1 - 0.0078 14.6 16.7 0.012 13.9 0.6 3.2 2 1 2 4 4 4 2 MFS/sugar transport protein OATP PF03137.15 AEO58463.1 - 0.016 13.2 0.7 0.033 12.2 0.1 1.8 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family ATG22 PF11700.3 AEO58463.1 - 0.22 9.9 22.7 0.0066 14.9 9.0 2.2 1 1 1 2 2 2 0 Vacuole effluxer Atg22 like MFS_1 PF07690.11 AEO58465.1 - 4e-31 108.0 28.6 4.5e-31 107.8 18.8 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily GFO_IDH_MocA_C PF02894.12 AEO58466.1 - 2.8e-17 62.5 0.7 3.9e-16 58.8 0.2 2.9 3 0 0 3 3 3 1 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.17 AEO58466.1 - 4e-16 59.6 0.0 6.6e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 AEO58466.1 - 0.1 13.0 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DUF2158 PF09926.4 AEO58467.1 - 0.13 11.7 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized small protein (DUF2158) PAT1 PF09770.4 AEO58467.1 - 0.79 7.8 11.9 0.95 7.6 8.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pex14_N PF04695.8 AEO58467.1 - 3.7 7.6 5.6 7 6.7 3.9 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MFS_1 PF07690.11 AEO58470.1 - 2.6e-32 111.9 36.6 2.6e-30 105.3 17.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily UPF0060 PF02694.10 AEO58470.1 - 0.033 14.2 0.5 0.033 14.2 0.3 2.9 3 0 0 3 3 3 0 Uncharacterised BCR, YnfA/UPF0060 family FAD_binding_3 PF01494.14 AEO58471.1 - 1.7e-17 63.5 0.1 1.4e-08 34.2 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 AEO58471.1 - 6.1e-06 25.3 0.3 0.039 12.8 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 AEO58471.1 - 0.0033 17.8 0.0 0.059 13.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AEO58471.1 - 0.014 15.4 0.0 0.054 13.5 0.0 2.1 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain PhnH PF05845.7 AEO58471.1 - 0.068 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial phosphonate metabolism protein (PhnH) DUF3429 PF11911.3 AEO58473.1 - 1.7e-39 135.0 11.2 2.4e-39 134.5 7.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) Zip PF02535.17 AEO58473.1 - 0.15 11.0 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter IncA PF04156.9 AEO58473.1 - 0.16 11.5 2.2 0.33 10.5 1.5 1.5 1 0 0 1 1 1 0 IncA protein Med19 PF10278.4 AEO58473.1 - 5 6.7 18.8 1.7 8.2 9.7 2.1 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 NARP1 PF12569.3 AEO58473.1 - 8.9 4.9 23.9 14 4.3 16.5 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF1162 PF06650.7 AEO58474.1 - 2.5e-88 295.8 0.0 8.2e-85 284.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1162) Chorein_N PF12624.2 AEO58474.1 - 2.6e-42 143.0 0.1 7.5e-42 141.5 0.1 1.9 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 AEO58474.1 - 1.4e-05 25.1 0.0 8.8e-05 22.5 0.0 2.4 2 0 0 2 2 2 1 ATG C terminal domain Methyltransf_23 PF13489.1 AEO58475.1 - 2.3e-19 69.7 0.0 3.5e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO58475.1 - 1.6e-15 57.3 0.0 3.8e-15 56.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO58475.1 - 1.7e-10 40.6 0.0 0.00051 19.6 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 AEO58475.1 - 6.3e-09 36.2 0.0 1.1e-07 32.2 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO58475.1 - 2.4e-08 34.5 0.0 5.7e-07 30.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AEO58475.1 - 4.2e-08 32.6 0.0 5.8e-07 28.8 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 AEO58475.1 - 1.6e-07 31.5 0.0 7.3e-07 29.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO58475.1 - 6.7e-05 22.8 0.0 0.0002 21.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 AEO58475.1 - 0.0008 18.5 0.0 0.0074 15.3 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 AEO58475.1 - 0.0012 18.2 0.0 0.0071 15.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain DUF938 PF06080.7 AEO58475.1 - 0.019 14.5 0.0 0.15 11.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF938) PrmA PF06325.8 AEO58475.1 - 0.021 13.9 0.0 0.034 13.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.4 AEO58475.1 - 0.022 14.2 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_8 PF05148.10 AEO58475.1 - 0.047 13.3 0.0 0.22 11.1 0.0 1.9 2 0 0 2 2 2 0 Hypothetical methyltransferase FtsJ PF01728.14 AEO58475.1 - 0.14 12.0 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_2 PF00891.13 AEO58475.1 - 0.14 11.2 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase PCMT PF01135.14 AEO58475.1 - 0.15 11.5 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF3275 PF11679.3 AEO58475.1 - 1.8 8.1 7.8 3.1 7.3 5.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) Imm10 PF15562.1 AEO58477.1 - 0.16 11.7 1.0 0.38 10.5 0.7 1.6 1 0 0 1 1 1 0 Immunity protein 10 Sugar_tr PF00083.19 AEO58479.1 - 6.8e-118 394.0 30.4 7.8e-118 393.8 21.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO58479.1 - 8.2e-19 67.5 56.5 7.4e-15 54.5 24.6 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.20 AEO58481.1 - 4.9e-25 88.1 0.0 1e-24 87.0 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO58481.1 - 2e-12 46.7 0.0 3.3e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 AEO58481.1 - 0.0032 16.5 0.0 0.0047 16.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AEO58481.1 - 0.0055 16.4 0.1 0.012 15.3 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 AEO58481.1 - 0.079 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase rve PF00665.21 AEO58485.1 - 0.0031 17.6 0.0 0.0037 17.3 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 AEO58488.1 - 1.4e-07 31.1 0.8 1.5e-07 31.0 0.6 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Herpes_BBRF1 PF04793.7 AEO58489.1 - 0.024 13.4 0.0 0.025 13.3 0.0 1.1 1 0 0 1 1 1 0 BRRF1-like protein TPMT PF05724.6 AEO58491.1 - 0.017 14.5 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) WD40 PF00400.27 AEO58492.1 - 3.8e-75 245.3 20.5 6.7e-12 44.8 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 AEO58492.1 - 3.8e-10 38.5 2.0 0.00033 18.9 0.1 4.3 2 2 2 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 AEO58492.1 - 0.0011 17.7 0.1 0.26 10.0 0.0 3.2 1 1 2 3 3 3 1 Nup133 N terminal like bZIP_1 PF00170.16 AEO58492.1 - 0.073 13.0 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 bZIP transcription factor CLASP_N PF12348.3 AEO58493.1 - 7.8e-08 31.9 0.3 8.3e-06 25.3 0.1 2.5 2 0 0 2 2 2 1 CLASP N terminal HEAT PF02985.17 AEO58493.1 - 5.7e-07 29.0 6.7 0.24 11.5 0.0 5.9 6 0 0 6 6 6 2 HEAT repeat Adaptin_N PF01602.15 AEO58493.1 - 9.3e-06 24.2 0.9 0.052 11.8 0.1 3.7 2 2 2 4 4 4 2 Adaptin N terminal region HEAT_2 PF13646.1 AEO58493.1 - 2.1e-05 24.6 12.3 0.021 15.0 1.0 5.0 3 3 1 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 AEO58493.1 - 0.0034 17.8 5.7 1.1 9.7 0.2 4.8 4 0 0 4 4 4 1 HEAT-like repeat T2SF PF00482.18 AEO58493.1 - 0.13 12.2 1.6 1.3 8.9 0.1 3.1 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F Arm PF00514.18 AEO58493.1 - 0.13 12.1 2.1 42 4.1 0.1 4.3 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat APG6 PF04111.7 AEO58493.1 - 1.4 7.8 15.7 0.06 12.3 6.7 1.7 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF972 PF06156.8 AEO58493.1 - 2 8.8 6.5 36 4.7 0.7 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) NYD-SP28_assoc PF14775.1 AEO58493.1 - 5.7 6.7 7.3 1.2 8.8 1.0 2.7 2 1 0 2 2 2 0 Sperm tail C-terminal domain ADIP PF11559.3 AEO58493.1 - 8.7 6.2 14.9 64 3.4 10.3 2.4 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding Condensation PF00668.15 AEO58494.1 - 1.4e-92 309.7 0.0 3.3e-32 111.5 0.0 4.2 4 0 0 4 4 4 4 Condensation domain AMP-binding PF00501.23 AEO58494.1 - 1.9e-42 145.1 0.0 3.9e-42 144.1 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 AEO58494.1 - 9.2e-22 77.0 1.0 8.8e-09 35.5 0.1 4.4 4 0 0 4 4 4 3 Phosphopantetheine attachment site BSP_II PF05432.6 AEO58495.1 - 0.094 11.9 5.8 0.1 11.8 4.0 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Myc_N PF01056.13 AEO58495.1 - 0.12 11.5 3.3 0.14 11.3 2.3 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Nucleoplasmin PF03066.10 AEO58495.1 - 0.31 10.5 5.3 0.38 10.2 3.7 1.1 1 0 0 1 1 1 0 Nucleoplasmin A2L_zn_ribbon PF08792.5 AEO58495.1 - 0.5 9.8 2.3 0.56 9.7 0.1 2.0 2 0 0 2 2 2 0 A2L zinc ribbon domain CENP-B_dimeris PF09026.5 AEO58495.1 - 1.3 9.2 6.6 1.9 8.7 4.6 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Ribosomal_60s PF00428.14 AEO58495.1 - 5.8 7.3 14.1 9 6.7 9.8 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein VID27 PF08553.5 AEO58495.1 - 7.4 4.6 6.0 8.5 4.4 4.1 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein Cu-oxidase_2 PF07731.9 AEO58496.1 - 3.9e-41 139.7 4.8 5.8e-37 126.2 0.1 3.3 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 AEO58496.1 - 9.7e-36 122.0 7.6 2.4e-35 120.7 1.9 2.9 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 AEO58496.1 - 1.6e-35 122.3 0.0 3.3e-35 121.3 0.0 1.6 1 0 0 1 1 1 1 Multicopper oxidase DUF500 PF04366.7 AEO58498.1 - 3e-44 149.4 0.0 5.2e-44 148.7 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) Fringe PF02434.11 AEO58499.1 - 5.6e-07 29.0 0.0 1.1e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Fringe-like DUF604 PF04646.7 AEO58499.1 - 2.4e-05 23.6 0.0 7.5e-05 22.0 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF604 Hpt PF01627.18 AEO58500.1 - 0.26 11.3 4.1 0.2 11.7 0.3 2.4 2 0 0 2 2 2 0 Hpt domain VIT1 PF01988.14 AEO58501.1 - 7.4e-67 224.9 2.9 8.5e-67 224.7 2.0 1.0 1 0 0 1 1 1 1 VIT family Orai-1 PF07856.7 AEO58501.1 - 0.11 12.0 0.1 0.17 11.4 0.1 1.3 1 0 0 1 1 1 0 Mediator of CRAC channel activity ATP_synt_I PF03899.10 AEO58501.1 - 2.4 8.3 9.8 1.2 9.3 0.4 2.5 2 0 0 2 2 2 0 ATP synthase I chain Periviscerokin PF08259.6 AEO58501.1 - 9.9 6.6 6.4 9.4 6.6 0.6 2.8 2 0 0 2 2 2 0 Periviscerokinin family BRO1 PF03097.13 AEO58502.1 - 6.6e-117 390.4 0.0 1.1e-116 389.6 0.0 1.4 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 AEO58502.1 - 1e-81 274.1 3.0 1.9e-81 273.2 1.3 1.9 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV K-box PF01486.12 AEO58502.1 - 0.0025 17.5 0.4 0.0091 15.7 0.0 2.2 2 0 0 2 2 2 1 K-box region DHC_N1 PF08385.7 AEO58502.1 - 0.024 13.0 1.5 0.049 12.0 0.0 2.2 3 0 0 3 3 3 0 Dynein heavy chain, N-terminal region 1 IncA PF04156.9 AEO58502.1 - 3.7 7.0 8.2 2.6 7.6 3.1 2.5 2 0 0 2 2 2 0 IncA protein p450 PF00067.17 AEO58503.1 - 5.2e-43 147.2 0.0 6.4e-43 146.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.21 AEO58504.1 - 1.3e-26 92.6 2.1 1.9e-26 92.1 1.5 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AEO58504.1 - 1.7e-22 79.2 0.0 2.6e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain GIDA PF01134.17 AEO58504.1 - 0.0048 15.7 1.8 0.0065 15.3 1.3 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A NADH_4Fe-4S PF10589.4 AEO58504.1 - 0.028 13.5 2.3 0.077 12.1 1.6 1.7 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 2-Hacid_dh_C PF02826.14 AEO58504.1 - 0.1 11.7 0.1 0.18 10.9 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MTS PF05175.9 AEO58504.1 - 0.14 11.4 0.1 0.23 10.8 0.1 1.2 1 0 0 1 1 1 0 Methyltransferase small domain MFS_1 PF07690.11 AEO58505.1 - 1.1e-16 60.4 35.4 1.1e-16 60.4 24.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO58505.1 - 0.0003 19.4 9.1 0.0003 19.4 6.3 2.5 2 1 1 3 3 3 1 Sugar (and other) transporter DUF3938 PF13074.1 AEO58505.1 - 0.068 13.0 1.0 0.24 11.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3938) ATP-synt_C PF00137.16 AEO58506.1 - 3.1e-16 59.0 14.8 6.8e-16 57.9 10.3 1.6 1 0 0 1 1 1 1 ATP synthase subunit C Alpha-amylase PF00128.19 AEO58507.1 - 1.3e-19 70.7 0.0 8.6e-19 68.0 0.0 1.9 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.11 AEO58507.1 - 5.7e-06 24.4 0.0 0.04 11.6 0.0 2.6 3 0 0 3 3 3 2 Glycosyl hydrolase family 70 DUF1939 PF09154.5 AEO58507.1 - 0.15 11.9 0.2 0.32 10.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1939) Motile_Sperm PF00635.21 AEO58509.1 - 0.1 12.2 0.0 0.26 10.9 0.0 1.6 2 0 0 2 2 2 0 MSP (Major sperm protein) domain GPI-anchored PF10342.4 AEO58509.1 - 0.27 11.7 3.1 7 7.1 0.0 2.7 2 1 0 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Band_7 PF01145.20 AEO58510.1 - 4.7e-14 52.6 0.0 4.7e-14 52.6 0.0 2.9 2 1 0 2 2 2 1 SPFH domain / Band 7 family DUF3986 PF13143.1 AEO58510.1 - 0.042 14.2 0.2 14 6.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3986) Cnd2 PF05786.9 AEO58511.1 - 0.093 11.2 4.1 0.13 10.7 2.9 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 Nucleoplasmin PF03066.10 AEO58511.1 - 0.19 11.2 1.6 0.33 10.4 1.1 1.3 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 AEO58511.1 - 0.19 12.0 9.3 0.4 11.0 6.4 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Spt5_N PF11942.3 AEO58511.1 - 1 10.0 10.3 2 9.1 7.1 1.4 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal FAD_binding_4 PF01565.18 AEO58513.1 - 6.4e-27 93.7 1.8 6.4e-27 93.7 1.2 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 AEO58513.1 - 4.7e-13 48.8 0.2 9.6e-13 47.8 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like IATP PF04568.7 AEO58514.1 - 2.6 8.1 9.1 1.8 8.6 5.4 1.4 1 1 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP Peptidase_S49_N PF08496.5 AEO58514.1 - 7.8 6.2 7.9 7.9 6.2 5.4 1.0 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Pec_lyase_C PF00544.14 AEO58515.1 - 8.8e-20 71.0 5.7 1.4e-19 70.3 4.0 1.3 1 0 0 1 1 1 1 Pectate lyase TauD PF02668.11 AEO58516.1 - 8.9e-52 176.3 0.0 1.5e-51 175.5 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 AEO58516.1 - 0.0051 15.7 0.0 0.0089 14.9 0.0 1.3 1 0 0 1 1 1 1 CsiD PhyH PF05721.8 AEO58516.1 - 0.013 15.5 0.0 7.5 6.5 0.0 2.6 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) DUF971 PF06155.7 AEO58516.1 - 0.014 15.8 0.0 0.056 13.8 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF971) 2OG-FeII_Oxy_3 PF13640.1 AEO58516.1 - 0.03 14.8 0.0 0.11 12.9 0.0 2.1 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily CUE PF02845.11 AEO58517.1 - 9.5e-08 31.3 0.1 1.8e-07 30.5 0.1 1.5 1 0 0 1 1 1 1 CUE domain zf-CCCH PF00642.19 AEO58518.1 - 0.00011 21.7 3.3 0.00021 20.8 2.3 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nucleoporin_FG PF13634.1 AEO58518.1 - 0.00038 20.6 117.1 0.023 14.9 28.2 4.6 1 1 2 3 3 3 2 Nucleoporin FG repeat region p450 PF00067.17 AEO58519.1 - 2.7e-65 220.6 0.0 3.6e-65 220.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3649 PF12365.3 AEO58519.1 - 0.13 11.8 0.5 0.34 10.4 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3649) Cellulase PF00150.13 AEO58520.1 - 4.8e-20 71.9 0.3 1.4e-19 70.4 0.2 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_72 PF03198.9 AEO58522.1 - 1e-07 31.3 0.0 1.3e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase DUF2384 PF09722.5 AEO58523.1 - 0.12 12.2 0.4 0.37 10.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2384) Frag1 PF10277.4 AEO58524.1 - 9.4e-42 142.9 14.7 2.4e-41 141.6 5.8 2.8 2 0 0 2 2 2 2 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.18 AEO58524.1 - 0.00061 19.8 0.1 0.0013 18.7 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Glyco_hydro_68 PF02435.11 AEO58524.1 - 0.25 10.0 0.3 0.42 9.2 0.2 1.2 1 0 0 1 1 1 0 Levansucrase/Invertase U3_assoc_6 PF08640.6 AEO58525.1 - 1e-24 86.1 0.0 2.4e-24 84.9 0.0 1.6 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.1 AEO58525.1 - 8.9e-05 22.8 3.5 0.016 15.7 0.4 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat NRDE-2 PF08424.5 AEO58525.1 - 0.00076 18.4 0.0 0.14 11.0 0.0 2.2 1 1 1 2 2 2 2 NRDE-2, necessary for RNA interference TPR_11 PF13414.1 AEO58525.1 - 0.013 15.1 0.3 0.062 12.9 0.1 2.1 1 1 1 2 2 2 0 TPR repeat TPR_17 PF13431.1 AEO58525.1 - 0.049 13.8 0.0 3.2 8.1 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat EVE PF01878.13 AEO58526.1 - 2.5e-27 95.6 0.0 3.7e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 EVE domain adh_short PF00106.20 AEO58527.1 - 9.9e-09 35.3 0.0 1.5e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 AEO58527.1 - 1.1e-06 28.2 0.0 1.5e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 AEO58527.1 - 1.6e-06 28.2 0.0 2.7e-06 27.5 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding F420_oxidored PF03807.12 AEO58527.1 - 0.0032 17.8 0.1 0.013 15.8 0.1 2.1 2 1 1 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.12 AEO58527.1 - 0.0093 14.8 0.0 0.011 14.6 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short_C2 PF13561.1 AEO58527.1 - 0.015 15.0 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.8 AEO58527.1 - 0.016 14.4 0.0 0.029 13.6 0.0 1.3 1 1 0 1 1 1 0 NmrA-like family TrkA_N PF02254.13 AEO58527.1 - 0.053 13.5 0.0 0.082 12.9 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain KR PF08659.5 AEO58527.1 - 0.13 11.9 0.0 0.35 10.5 0.0 1.7 1 1 0 1 1 1 0 KR domain ARID PF01388.16 AEO58528.1 - 3.1e-19 68.6 0.0 1e-18 66.9 0.0 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain FixO PF02433.10 AEO58528.1 - 5.3 6.3 10.5 10 5.4 7.3 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO Phage_GPD PF05954.6 AEO58528.1 - 9.4 5.3 9.7 16 4.5 6.7 1.2 1 0 0 1 1 1 0 Phage late control gene D protein (GPD) Img2 PF05046.9 AEO58529.1 - 3.4e-21 75.2 0.0 4.5e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) SUI1 PF01253.17 AEO58529.1 - 0.011 15.4 0.2 0.023 14.5 0.1 1.5 1 1 0 1 1 1 0 Translation initiation factor SUI1 Dicty_REP PF05086.7 AEO58529.1 - 0.19 9.4 0.6 0.2 9.3 0.4 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein AflR PF08493.5 AEO58529.1 - 7.7 5.4 9.3 9.3 5.1 6.4 1.1 1 0 0 1 1 1 0 Aflatoxin regulatory protein eIF3_N PF09440.5 AEO58530.1 - 8.3e-51 171.6 4.8 4.4e-50 169.3 3.6 2.1 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 AEO58530.1 - 1.4e-15 57.5 0.1 4.3e-15 55.9 0.1 1.9 1 0 0 1 1 1 1 PCI domain PCI_Csn8 PF10075.4 AEO58530.1 - 0.00082 19.1 0.1 0.0027 17.4 0.0 2.0 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 RPN7 PF10602.4 AEO58530.1 - 0.015 14.6 0.2 0.029 13.7 0.1 1.6 1 1 0 1 1 1 0 26S proteasome subunit RPN7 TPR_6 PF13174.1 AEO58530.1 - 0.033 14.6 0.1 3.2 8.4 0.1 3.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 AEO58530.1 - 0.044 13.4 0.2 0.15 11.6 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat HTH_AsnC-type PF13404.1 AEO58530.1 - 0.12 11.9 0.3 0.58 9.7 0.0 2.3 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain TPR_2 PF07719.12 AEO58530.1 - 0.23 11.4 1.5 0.63 10.0 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat PC_rep PF01851.17 AEO58531.1 - 1.5e-11 43.8 0.1 0.00061 19.8 0.0 4.4 3 0 0 3 3 3 3 Proteasome/cyclosome repeat Apc1 PF12859.2 AEO58531.1 - 0.0024 18.0 0.0 0.0068 16.6 0.0 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 DUF3208 PF11482.3 AEO58531.1 - 0.01 15.9 0.1 0.047 13.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3208) Clathrin PF00637.15 AEO58532.1 - 1.1e-19 70.4 0.1 8.1e-19 67.6 0.0 2.3 3 0 0 3 3 3 1 Region in Clathrin and VPS WD40 PF00400.27 AEO58532.1 - 3.5e-07 29.8 0.1 0.0016 18.2 0.0 3.7 3 1 0 3 3 3 2 WD domain, G-beta repeat zf-RING_2 PF13639.1 AEO58532.1 - 0.0016 18.2 1.2 0.0053 16.5 0.8 1.9 1 1 0 1 1 1 1 Ring finger domain Vps39_1 PF10366.4 AEO58532.1 - 0.017 15.1 0.1 0.095 12.7 0.0 2.2 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 zf-RING_5 PF14634.1 AEO58532.1 - 0.02 14.6 0.1 0.02 14.6 0.0 1.7 2 0 0 2 2 1 0 zinc-RING finger domain Nop14 PF04147.7 AEO58532.1 - 0.27 9.0 19.9 0.45 8.3 13.8 1.2 1 0 0 1 1 1 0 Nop14-like family RXT2_N PF08595.6 AEO58532.1 - 1.2 8.9 9.4 2.6 7.8 6.5 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal VID27 PF08553.5 AEO58532.1 - 1.7 6.7 7.4 2.6 6.1 5.1 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein NOA36 PF06524.7 AEO58532.1 - 1.9 7.6 13.2 3.3 6.8 9.2 1.3 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.7 AEO58532.1 - 2.5 7.2 16.9 1.3 8.1 10.2 1.5 2 0 0 2 2 2 0 SDA1 Daxx PF03344.10 AEO58532.1 - 2.8 6.2 23.9 0.76 8.1 14.3 1.7 2 0 0 2 2 2 0 Daxx Family DNA_pol_phi PF04931.8 AEO58532.1 - 3 5.5 21.4 4.4 4.9 14.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.9 AEO58532.1 - 4.7 5.1 12.4 9.1 4.1 8.6 1.3 1 0 0 1 1 1 0 CDC45-like protein GST_C PF00043.20 AEO58533.1 - 5.2e-14 51.9 0.0 8.1e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 AEO58533.1 - 7.4e-13 48.4 0.1 9.9e-11 41.6 0.0 2.5 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 AEO58533.1 - 1.2e-10 41.1 0.0 1.8e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 AEO58533.1 - 8.8e-07 29.0 0.0 1.5e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 AEO58533.1 - 2.8e-06 27.7 0.0 4.3e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 AEO58533.1 - 5.8e-06 26.2 0.0 2.5e-05 24.2 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain RVT_1 PF00078.22 AEO58535.1 - 0.003 16.9 1.0 0.0031 16.9 0.7 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3786 PF12654.2 AEO58535.1 - 0.036 13.3 0.3 0.044 13.0 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3786) Apq12 PF12716.2 AEO58535.1 - 0.38 10.4 3.4 1.1 9.0 2.2 1.9 1 1 0 1 1 1 0 Nuclear pore assembly and biogenesis Leukemia_assc_2 PF15197.1 AEO58535.1 - 3.9 7.2 8.6 1.9 8.2 0.1 2.7 2 1 0 2 2 2 0 Leukemia-associated protein 2 Pkinase PF00069.20 AEO58537.1 - 3.6e-08 32.8 0.0 5.2e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 AEO58537.1 - 1.1e-05 25.2 0.2 2.1e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 AEO58537.1 - 4.5e-05 22.6 0.0 7.1e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DIM PF08194.7 AEO58539.1 - 0.026 14.4 3.3 0.056 13.4 2.3 1.6 1 0 0 1 1 1 0 DIM protein GCFC PF07842.7 AEO58541.1 - 1.3e-78 264.1 3.0 2.3e-78 263.3 2.1 1.4 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 AEO58541.1 - 9.1e-15 54.1 1.5 9.1e-15 54.1 1.0 2.1 2 0 0 2 2 2 1 G-patch domain TIP_N PF12457.3 AEO58541.1 - 2.8e-14 53.1 15.6 2.8e-14 53.1 10.8 2.7 3 0 0 3 3 3 1 Tuftelin interacting protein N terminal G-patch_2 PF12656.2 AEO58541.1 - 2.7e-09 36.7 0.9 2.7e-09 36.7 0.6 3.1 4 0 0 4 4 4 1 DExH-box splicing factor binding site Daxx PF03344.10 AEO58541.1 - 0.39 9.1 19.5 0.093 11.2 9.5 2.1 2 0 0 2 2 2 0 Daxx Family FUSC PF04632.7 AEO58541.1 - 5.4 5.3 6.9 7 4.9 4.4 1.4 1 1 0 1 1 1 0 Fusaric acid resistance protein family EF-hand_1 PF00036.27 AEO58542.1 - 6.4e-37 122.0 10.2 4.7e-09 34.8 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 AEO58542.1 - 8.4e-33 112.3 6.5 1.5e-16 60.2 0.9 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 AEO58542.1 - 2.6e-29 98.4 7.9 2e-08 33.4 0.0 4.1 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 AEO58542.1 - 3e-28 97.1 9.1 1e-12 47.4 0.2 3.4 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 AEO58542.1 - 1.1e-26 90.8 10.6 1.3e-07 30.6 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 AEO58542.1 - 4.4e-16 58.5 0.1 4e-08 33.0 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 AEO58542.1 - 9.6e-12 44.5 1.1 3.7e-05 23.4 0.1 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 AEO58542.1 - 1.2e-05 25.3 0.0 0.16 11.9 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region TerB PF05099.8 AEO58542.1 - 9.7e-05 22.1 0.1 0.086 12.5 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB UPF0154 PF03672.8 AEO58542.1 - 0.0068 15.9 0.0 2.2 7.9 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) Caleosin PF05042.8 AEO58542.1 - 0.015 14.8 0.2 1.3 8.5 0.1 3.2 1 1 1 2 2 2 0 Caleosin related protein RTX_C PF08339.5 AEO58542.1 - 0.015 14.9 0.5 2.2 7.9 0.0 2.2 1 1 0 2 2 2 0 RTX C-terminal domain EFhand_Ca_insen PF08726.5 AEO58542.1 - 0.016 15.1 0.1 0.037 13.9 0.0 1.7 2 0 0 2 2 2 0 Ca2+ insensitive EF hand Toprim_2 PF13155.1 AEO58542.1 - 0.031 14.5 0.3 1.4 9.2 0.0 2.1 1 1 1 2 2 2 0 Toprim-like PepSY_2 PF13670.1 AEO58542.1 - 0.11 12.4 0.0 4 7.4 0.0 2.3 2 1 0 2 2 2 0 Peptidase propeptide and YPEB domain PMBR PF09373.5 AEO58542.1 - 0.11 12.4 0.1 15 5.7 0.0 3.3 3 0 0 3 3 3 0 Pseudomurein-binding repeat EF-hand_10 PF14788.1 AEO58542.1 - 0.11 12.1 2.3 0.51 10.0 0.1 2.8 2 1 2 4 4 4 0 EF hand VCBS PF13517.1 AEO58542.1 - 1.2 9.5 6.0 9.6 6.6 2.2 2.6 1 1 1 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella MFS_1 PF07690.11 AEO58543.1 - 9.3e-31 106.8 32.8 9.3e-31 106.8 22.7 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO58543.1 - 7.6e-11 41.2 7.5 7.6e-11 41.2 5.2 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter Ldr_toxin PF13940.1 AEO58543.1 - 0.17 11.6 5.6 7.4 6.4 1.5 3.1 2 0 0 2 2 2 0 Toxin Ldr, type I toxin-antitoxin system Pkinase PF00069.20 AEO58544.1 - 8.4e-25 87.3 0.0 2.7e-24 85.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO58544.1 - 1.9e-09 37.0 0.0 4.8e-09 35.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase PBP_GOBP PF01395.17 AEO58544.1 - 0.052 13.1 0.0 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 PBP/GOBP family Kdo PF06293.9 AEO58544.1 - 0.15 11.1 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Lyase_aromatic PF00221.14 AEO58546.1 - 8.6e-12 44.2 0.0 8.6e-12 44.2 0.0 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase adh_short PF00106.20 AEO58547.1 - 2.9e-29 102.1 0.4 4e-29 101.6 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO58547.1 - 1.8e-24 86.8 0.0 2.2e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO58547.1 - 2.3e-15 56.6 0.1 3.4e-15 56.1 0.1 1.1 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.21 AEO58547.1 - 0.0014 18.1 0.7 0.39 10.2 0.5 2.3 1 1 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 AEO58547.1 - 0.015 15.2 0.7 0.03 14.3 0.5 1.6 1 1 0 1 1 1 0 NADH(P)-binding DUF1372 PF07116.6 AEO58547.1 - 0.028 14.3 0.1 0.075 12.9 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1372) Epimerase PF01370.16 AEO58547.1 - 0.044 13.2 0.5 0.09 12.1 0.3 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 AEO58547.1 - 0.078 12.0 0.1 0.16 11.0 0.1 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Acyl-CoA_dh_2 PF08028.6 AEO58548.1 - 1.5e-19 70.6 0.7 2.1e-19 70.1 0.5 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_1 PF00441.19 AEO58548.1 - 0.00035 20.7 0.2 0.00078 19.5 0.2 1.7 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF2190 PF09956.4 AEO58548.1 - 0.019 14.7 0.1 0.064 13.0 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2190) SAPS PF04499.10 AEO58549.1 - 1.1e-197 657.3 0.0 5.8e-197 655.0 0.0 2.1 2 0 0 2 2 2 1 SIT4 phosphatase-associated protein Abhydrolase_3 PF07859.8 AEO58550.1 - 3.8e-29 101.7 0.5 1.2e-28 100.1 0.4 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 AEO58550.1 - 0.00042 19.1 0.0 0.00066 18.5 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family DUF1858 PF08984.6 AEO58550.1 - 0.2 11.3 0.0 0.36 10.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1858) DUF3966 PF13110.1 AEO58550.1 - 0.22 11.3 0.0 0.4 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3966) MFS_1 PF07690.11 AEO58551.1 - 3.2e-33 114.9 38.0 5.4e-33 114.1 26.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2457 PF10446.4 AEO58551.1 - 2.9 6.5 12.2 4.5 5.8 8.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SET PF00856.23 AEO58552.1 - 0.0081 16.4 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 1 SET domain Polysacc_deac_1 PF01522.16 AEO58553.1 - 6.5e-30 103.3 0.0 8.7e-30 102.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 AEO58553.1 - 3.8e-05 22.7 0.0 5.6e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Pyr_redox_3 PF13738.1 AEO58557.1 - 1.2e-24 87.4 0.2 3e-24 86.2 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 AEO58557.1 - 1.7e-11 43.0 0.0 2.3e-10 39.3 0.0 2.5 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 AEO58557.1 - 6.5e-10 38.8 0.0 1e-07 31.8 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 AEO58557.1 - 3.2e-07 29.5 0.8 0.0015 17.5 0.0 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.12 AEO58557.1 - 9.7e-07 28.1 0.0 0.0011 18.1 0.0 2.4 2 0 0 2 2 2 2 Thi4 family Pyr_redox_2 PF07992.9 AEO58557.1 - 5.2e-05 23.2 0.4 0.76 9.6 0.0 3.4 2 2 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AEO58557.1 - 9.3e-05 22.7 0.1 0.047 14.0 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 AEO58557.1 - 0.00011 21.2 0.2 0.0068 15.3 0.1 2.9 2 1 0 2 2 2 1 Lycopene cyclase protein K_oxygenase PF13434.1 AEO58557.1 - 0.00094 18.1 1.8 0.029 13.2 0.0 3.3 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 AEO58557.1 - 0.011 15.4 0.3 15 5.3 0.0 3.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding Shikimate_DH PF01488.15 AEO58557.1 - 0.012 15.7 0.1 0.041 13.9 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 AEO58557.1 - 0.012 14.4 0.2 0.047 12.5 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.1 AEO58557.1 - 0.03 14.5 0.0 0.11 12.7 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding GIDA PF01134.17 AEO58557.1 - 0.16 10.7 0.5 0.85 8.4 0.1 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A PhyH PF05721.8 AEO58558.1 - 0.065 13.2 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) p450 PF00067.17 AEO58559.1 - 4.3e-76 256.2 0.0 5.5e-76 255.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.13 AEO58560.1 - 3.6e-08 33.1 11.4 6.6e-08 32.3 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 AEO58560.1 - 3.5e-05 22.5 0.0 5.8e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain BAF1_ABF1 PF04684.8 AEO58560.1 - 0.57 8.9 11.6 0.92 8.2 8.1 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor adh_short PF00106.20 AEO58561.1 - 4.5e-28 98.2 1.4 4.5e-28 98.2 0.9 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO58561.1 - 2.1e-10 40.8 0.0 3.3e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO58561.1 - 1.5e-07 31.2 7.1 1.6e-07 31.1 3.1 2.3 2 1 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 AEO58561.1 - 0.0014 18.6 0.4 0.0035 17.3 0.3 1.7 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 AEO58561.1 - 0.0015 18.0 0.1 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 AEO58561.1 - 0.0017 17.1 0.1 0.0025 16.5 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family HTH_IclR PF09339.5 AEO58561.1 - 0.0081 15.7 1.0 0.02 14.4 0.7 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain 2-Hacid_dh_C PF02826.14 AEO58561.1 - 0.0099 15.0 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Abhydrolase_3 PF07859.8 AEO58562.1 - 1.1e-26 93.7 0.3 1.9e-26 92.9 0.2 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Pyr_redox_3 PF13738.1 AEO58562.1 - 5.2e-26 91.9 0.0 9.3e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 AEO58562.1 - 1.3e-11 43.4 0.0 5e-11 41.4 0.0 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like DUF2424 PF10340.4 AEO58562.1 - 3.1e-10 39.2 0.0 6.9e-10 38.1 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) NAD_binding_8 PF13450.1 AEO58562.1 - 4.5e-09 36.2 0.0 3.8e-07 30.0 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 AEO58562.1 - 3.8e-06 26.1 0.0 0.0004 19.5 0.0 2.2 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.1 AEO58562.1 - 0.00012 21.1 0.0 0.00092 18.2 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 AEO58562.1 - 0.00017 20.6 1.0 0.038 12.8 0.0 2.9 2 1 0 2 2 2 2 FAD dependent oxidoreductase Abhydrolase_5 PF12695.2 AEO58562.1 - 0.00039 20.2 0.5 0.0014 18.4 0.3 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family Pyr_redox PF00070.22 AEO58562.1 - 0.0051 17.1 0.3 0.67 10.3 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 AEO58562.1 - 0.0087 14.9 0.8 0.065 12.0 0.1 2.4 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_2 PF07992.9 AEO58562.1 - 0.0098 15.7 0.1 3.2 7.5 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 AEO58562.1 - 0.02 14.9 0.0 0.82 9.7 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase CRAL_TRIO PF00650.15 AEO58563.1 - 2.6e-40 137.5 0.0 3.6e-40 137.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 AEO58563.1 - 1.5e-10 41.0 0.3 4.1e-10 39.6 0.2 1.9 1 1 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 AEO58563.1 - 6e-10 39.2 0.0 9.7e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Ret_tiss PF10044.4 AEO58564.1 - 0.024 15.1 0.0 13 6.3 0.0 3.6 2 1 1 3 3 3 0 Retinal tissue protein adh_short PF00106.20 AEO58564.1 - 0.064 13.1 0.2 0.21 11.5 0.0 1.9 2 0 0 2 2 2 0 short chain dehydrogenase ACT_3 PF10000.4 AEO58564.1 - 8.7 6.1 8.1 55 3.5 0.1 5.1 3 2 2 5 5 5 0 ACT domain DUF3712 PF12505.3 AEO58565.1 - 1.2e-22 80.2 0.0 2.3e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) TrkH PF02386.11 AEO58566.1 - 2.8e-76 256.3 8.2 1.3e-47 162.1 0.3 3.0 3 0 0 3 3 3 3 Cation transport protein DIOX_N PF14226.1 AEO58567.1 - 0.0001 22.8 0.0 0.00027 21.4 0.0 1.7 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 AEO58567.1 - 0.00013 22.1 0.0 0.00024 21.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Asp PF00026.18 AEO58568.1 - 1.2e-40 139.7 1.2 1.7e-40 139.2 0.8 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease CopD PF05425.8 AEO58569.1 - 0.025 14.7 2.8 0.039 14.1 1.9 1.3 1 1 0 1 1 1 0 Copper resistance protein D CoatB PF10389.4 AEO58569.1 - 1.9 8.4 6.0 1.5 8.7 0.8 2.6 2 1 1 3 3 3 0 Bacteriophage coat protein B Glycoprotein_B PF00606.13 AEO58569.1 - 4.6 5.1 4.9 14 3.5 3.4 1.8 1 1 0 1 1 1 0 Herpesvirus Glycoprotein B Peptidase_C2 PF00648.16 AEO58570.1 - 3.5e-52 177.2 1.7 9.1e-36 123.3 0.7 2.3 2 0 0 2 2 2 2 Calpain family cysteine protease GATase PF00117.23 AEO58572.1 - 4e-07 29.6 0.0 5.5e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Ribosomal_S7e PF01251.13 AEO58573.1 - 1.7e-82 275.5 0.6 1.9e-82 275.3 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e ADH_N PF08240.7 AEO58575.1 - 3.6e-26 91.0 2.7 5.8e-26 90.3 1.9 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AEO58575.1 - 1.5e-16 60.1 0.1 3.8e-16 58.8 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 AEO58575.1 - 6.6e-06 25.3 0.1 1.2e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 AEO58575.1 - 0.1 12.0 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Dynactin_p62 PF05502.8 AEO58576.1 - 1e-183 611.5 0.0 1.2e-183 611.3 0.0 1.0 1 0 0 1 1 1 1 Dynactin p62 family DUF4519 PF15012.1 AEO58576.1 - 0.029 14.2 0.7 0.076 12.9 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) BolA PF01722.13 AEO58578.1 - 1.8e-15 56.6 0.0 3e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 BolA-like protein Peptidase_S8 PF00082.17 AEO58579.1 - 1.5e-47 162.1 0.0 2.9e-47 161.1 0.0 1.5 1 1 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 AEO58579.1 - 4.3e-17 62.5 1.3 5.5e-17 62.1 0.1 1.8 2 0 0 2 2 2 1 Fn3-like domain (DUF1034) PA PF02225.17 AEO58579.1 - 6.1e-12 45.1 0.1 3.7e-11 42.5 0.0 2.3 2 0 0 2 2 2 1 PA domain FlgD_ig PF13860.1 AEO58579.1 - 1.9e-06 27.4 0.1 1.7e-05 24.4 0.0 2.5 2 0 0 2 2 2 1 FlgD Ig-like domain Apocytochr_F_C PF01333.14 AEO58579.1 - 0.0024 17.7 0.1 0.0053 16.5 0.0 1.5 1 0 0 1 1 1 1 Apocytochrome F, C-terminal MGC-24 PF05283.6 AEO58580.1 - 0.56 9.9 9.7 0.91 9.2 6.8 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) DIM PF08194.7 AEO58581.1 - 0.025 14.5 0.1 0.15 12.0 0.0 2.2 2 0 0 2 2 2 0 DIM protein FAD_binding_8 PF08022.7 AEO58583.1 - 2.9e-16 59.2 0.0 8.4e-16 57.7 0.0 1.8 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 AEO58583.1 - 1.5e-12 47.7 0.0 2.1e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 AEO58583.1 - 1.5e-12 47.6 12.7 1.5e-12 47.6 8.8 2.1 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 AEO58583.1 - 0.004 17.2 0.0 0.0093 16.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain DUF4405 PF14358.1 AEO58583.1 - 0.42 10.7 10.3 3.7 7.7 0.9 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) tRNA-synt_1d PF00750.14 AEO58584.1 - 4.1e-83 279.1 1.4 7.7e-83 278.2 0.9 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 AEO58584.1 - 4e-27 94.5 1.4 4.9e-27 94.2 0.1 1.9 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 AEO58584.1 - 0.00023 21.6 0.0 0.00078 19.9 0.0 2.0 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain p450 PF00067.17 AEO58585.1 - 7.2e-27 94.0 0.0 8.8e-27 93.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 SLAC1 PF03595.12 AEO58587.1 - 6.4e-82 274.8 38.6 7.3e-82 274.6 26.7 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF161 PF02588.10 AEO58587.1 - 3.8 7.8 8.7 0.6 10.4 1.5 2.6 2 0 0 2 2 2 0 Uncharacterized BCR, YitT family COG1284 RINGv PF12906.2 AEO58588.1 - 9.9e-17 60.7 8.8 1.6e-16 60.0 6.1 1.3 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 AEO58588.1 - 0.021 14.6 8.0 0.036 13.8 5.5 1.4 1 0 0 1 1 1 0 Ring finger domain zf-Apc11 PF12861.2 AEO58588.1 - 0.13 12.0 3.4 0.26 11.1 2.4 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 AEO58588.1 - 3 7.5 6.5 5 6.7 4.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DnaJ_CXXCXGXG PF00684.14 AEO58588.1 - 4 7.5 3.3 7.6 6.6 2.3 1.4 1 0 0 1 1 1 0 DnaJ central domain HeLo PF14479.1 AEO58590.1 - 9.6e-07 28.7 9.3 1.7e-05 24.6 1.0 3.6 2 1 0 2 2 2 1 Prion-inhibition and propagation DUF3405 PF11885.3 AEO58591.1 - 9.4e-155 515.6 0.6 1.1e-154 515.3 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Ole-e-6 PF09253.5 AEO58592.1 - 5.2 6.7 8.5 24 4.6 4.4 2.6 1 1 2 3 3 3 0 Pollen allergen ole e 6 HisKA PF00512.20 AEO58593.1 - 6.1e-07 29.3 0.4 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain LANC_like PF05147.8 AEO58594.1 - 1.7e-23 82.8 0.0 4.1e-22 78.2 0.0 2.0 2 0 0 2 2 2 2 Lanthionine synthetase C-like protein K_channel_TID PF07941.6 AEO58594.1 - 2.3 8.4 10.7 0.54 10.5 3.0 2.5 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Apolipoprotein PF01442.13 AEO58595.1 - 0.0002 20.9 10.0 0.022 14.2 4.2 3.4 1 1 1 2 2 2 1 Apolipoprotein A1/A4/E domain Alpha-E PF04168.7 AEO58595.1 - 0.05 12.9 1.9 0.18 11.1 0.0 2.6 3 0 0 3 3 3 0 A predicted alpha-helical domain with a conserved ER motif. Syntaxin_2 PF14523.1 AEO58595.1 - 0.075 13.0 7.5 11 6.0 1.5 4.5 2 2 2 4 4 4 0 Syntaxin-like protein DUF3223 PF11523.3 AEO58595.1 - 0.1 12.8 0.4 1.3 9.3 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3223) XH PF03469.9 AEO58595.1 - 0.25 11.0 8.0 9.8 5.8 0.0 3.6 2 1 0 3 3 3 0 XH domain DUF883 PF05957.8 AEO58595.1 - 3.1 8.2 23.1 4.5 7.7 0.1 6.3 4 2 3 7 7 7 0 Bacterial protein of unknown function (DUF883) Epimerase PF01370.16 AEO58596.1 - 0.12 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Glyco_hydro_10 PF00331.15 AEO58598.1 - 2.3e-86 289.7 0.0 2.5e-86 289.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Peptidase_M14 PF00246.19 AEO58600.1 - 4.3e-20 72.4 0.1 4.5e-20 72.4 0.0 1.0 1 0 0 1 1 1 1 Zinc carboxypeptidase Fungal_trans PF04082.13 AEO58601.1 - 2.9e-20 72.2 2.6 4.8e-20 71.5 1.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO58601.1 - 6.6e-08 32.3 12.6 1.3e-07 31.4 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RdRP PF05183.7 AEO58602.1 - 1.7e-126 423.2 0.0 2.5e-126 422.7 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase EF-hand_9 PF14658.1 AEO58602.1 - 0.13 12.1 0.0 0.43 10.5 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain Trypan_PARP PF05887.6 AEO58603.1 - 4.9 6.9 6.1 11 5.8 4.2 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) IBR PF01485.16 AEO58605.1 - 3.7e-11 42.7 54.0 5.7e-07 29.3 4.8 4.7 4 1 0 4 4 4 3 IBR domain zf-RING_2 PF13639.1 AEO58605.1 - 0.024 14.4 7.0 0.024 14.4 4.8 4.4 3 2 1 4 4 4 0 Ring finger domain GMC_oxred_N PF00732.14 AEO58606.1 - 1.1e-34 120.0 0.0 1.5e-33 116.2 0.0 2.3 2 1 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 AEO58606.1 - 2.5e-23 82.9 0.0 4.4e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 AEO58606.1 - 0.00013 21.9 0.3 0.0003 20.7 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 AEO58606.1 - 0.0064 16.3 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 AEO58606.1 - 0.029 13.2 0.9 0.054 12.3 0.6 1.4 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.19 AEO58606.1 - 0.039 12.8 0.1 0.11 11.4 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 AEO58606.1 - 0.041 12.7 0.0 0.066 12.1 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 AEO58606.1 - 0.044 13.8 0.2 0.79 9.7 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 AEO58606.1 - 0.13 10.6 0.3 0.19 10.1 0.2 1.1 1 0 0 1 1 1 0 HI0933-like protein PEP_mutase PF13714.1 AEO58607.1 - 2.2e-06 27.0 0.1 2.3e-06 27.0 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Nucleo_P87 PF07267.6 AEO58608.1 - 0.098 11.3 1.2 0.12 11.0 0.8 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 COesterase PF00135.23 AEO58609.1 - 3.8e-15 55.5 1.4 1.8e-13 50.0 0.4 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 AEO58609.1 - 1.4e-06 28.0 0.0 2.4e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold BPD_transp_2 PF02653.11 AEO58609.1 - 0.033 13.1 0.1 2 7.2 0.0 2.1 2 0 0 2 2 2 0 Branched-chain amino acid transport system / permease component Peptidase_S9 PF00326.16 AEO58609.1 - 0.09 11.9 0.4 0.17 11.1 0.3 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family UDPGT PF00201.13 AEO58610.1 - 0.00094 17.8 0.0 0.0015 17.1 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Mid2 PF04478.7 AEO58612.1 - 0.077 12.4 0.0 0.077 12.4 0.0 2.2 3 0 0 3 3 3 0 Mid2 like cell wall stress sensor SOG2 PF10428.4 AEO58612.1 - 1.5 7.4 6.3 1.9 7.0 4.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein PseudoU_synth_1 PF01416.15 AEO58613.1 - 2.1e-22 79.5 0.0 2.7e-10 40.5 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase Med22 PF06179.7 AEO58614.1 - 8.5e-11 41.8 0.1 1.1e-10 41.5 0.1 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex MFS_1 PF07690.11 AEO58615.1 - 6.3e-49 166.5 32.3 6.3e-49 166.5 22.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO58615.1 - 4.4e-14 51.9 24.0 6.2e-14 51.4 16.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 AEO58615.1 - 3.4e-05 22.2 1.3 4.9e-05 21.7 0.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 AEO58615.1 - 0.01 13.9 4.0 0.0095 14.0 1.2 2.0 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF1304 PF06993.7 AEO58615.1 - 0.022 14.4 1.3 0.14 11.9 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1304) TMPIT PF07851.8 AEO58615.1 - 8.8 5.2 8.5 0.21 10.6 1.2 1.6 2 0 0 2 2 2 0 TMPIT-like protein RTA1 PF04479.8 AEO58616.1 - 1e-12 48.0 6.3 5.2e-12 45.7 4.4 1.9 1 1 0 1 1 1 1 RTA1 like protein DUF4131 PF13567.1 AEO58616.1 - 0.081 12.3 10.2 0.65 9.3 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF308 PF03729.8 AEO58616.1 - 0.16 11.9 10.9 0.55 10.2 1.0 2.8 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) MerC PF03203.9 AEO58616.1 - 0.18 12.1 8.4 0.75 10.1 3.0 2.4 1 1 1 2 2 2 0 MerC mercury resistance protein GPI2 PF06432.6 AEO58616.1 - 0.28 10.4 6.3 0.29 10.4 1.4 2.1 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase Fungal_trans_2 PF11951.3 AEO58617.1 - 7.7e-12 44.4 0.0 1.1e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO58617.1 - 0.0084 15.9 8.2 0.016 15.1 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3454 PF11936.3 AEO58617.1 - 0.025 14.7 0.8 0.053 13.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3454) RIO1 PF01163.17 AEO58619.1 - 2.1e-69 232.6 1.0 4.8e-69 231.5 0.0 2.0 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 AEO58619.1 - 2.4e-05 24.1 1.5 0.022 14.4 0.2 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 AEO58619.1 - 0.00038 19.5 0.4 0.0064 15.5 0.3 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APG17 PF04108.7 AEO58620.1 - 9.2e-102 340.9 0.0 1.2e-101 340.5 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 DUF4358 PF14270.1 AEO58620.1 - 0.021 14.7 0.1 0.078 12.8 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4358) PV-1 PF06637.6 AEO58620.1 - 0.025 13.1 3.4 1.3 7.4 0.1 2.3 2 0 0 2 2 2 0 PV-1 protein (PLVAP) Laminin_II PF06009.7 AEO58620.1 - 0.046 13.4 0.3 0.92 9.2 0.0 3.0 4 0 0 4 4 4 0 Laminin Domain II Hpt PF01627.18 AEO58620.1 - 0.073 13.0 0.4 0.073 13.0 0.2 3.1 3 1 0 3 3 3 0 Hpt domain IncA PF04156.9 AEO58620.1 - 0.25 10.9 3.9 0.32 10.5 1.4 2.3 2 1 0 2 2 2 0 IncA protein WXG100 PF06013.7 AEO58620.1 - 1 9.4 5.1 3.2 7.8 0.3 3.6 4 0 0 4 4 4 0 Proteins of 100 residues with WXG DUF972 PF06156.8 AEO58620.1 - 5.9 7.2 5.3 3 8.2 0.1 3.1 4 1 0 4 4 4 0 Protein of unknown function (DUF972) ADH_zinc_N_2 PF13602.1 AEO58621.1 - 4.4e-24 85.7 0.0 1e-23 84.6 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 AEO58621.1 - 1.3e-15 57.1 0.0 2.4e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Semialdhyde_dh PF01118.19 AEO58621.1 - 0.0031 17.8 0.0 0.094 13.0 0.0 2.3 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain ADH_N PF08240.7 AEO58621.1 - 0.0082 15.8 0.0 0.023 14.4 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DapB_N PF01113.15 AEO58621.1 - 0.033 14.0 0.0 0.076 12.9 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus CBM_21 PF03370.8 AEO58623.1 - 2.3e-34 117.7 1.8 4.1e-34 116.9 1.3 1.4 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit NACHT PF05729.7 AEO58625.1 - 2.7e-11 43.4 0.0 5.8e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 AEO58625.1 - 2.1e-07 31.1 0.0 3.2e-06 27.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 AEO58625.1 - 1.6e-05 24.9 0.3 4.9e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 AEO58625.1 - 7e-05 21.8 0.0 0.00018 20.4 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA PF00004.24 AEO58625.1 - 0.0012 19.0 0.0 0.0039 17.3 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 AEO58625.1 - 0.0031 16.5 0.0 0.0053 15.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 AEO58625.1 - 0.012 15.3 0.0 0.036 13.7 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain RNA_helicase PF00910.17 AEO58625.1 - 0.013 15.6 0.0 0.057 13.5 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.1 AEO58625.1 - 0.019 14.8 0.0 0.051 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 AEO58625.1 - 0.027 13.5 0.3 0.14 11.2 0.0 2.0 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 AEO58625.1 - 0.11 13.2 0.0 0.28 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 AEO58625.1 - 0.15 11.1 0.0 0.49 9.4 0.0 1.8 1 1 0 1 1 1 0 KaiC DUF221 PF02714.10 AEO58626.1 - 3.4e-103 344.9 12.0 5.4e-103 344.2 8.4 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 AEO58626.1 - 4e-31 107.6 0.1 1.9e-30 105.4 0.1 2.2 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 AEO58626.1 - 1.9e-22 78.9 0.3 1.5e-21 76.0 0.0 2.5 3 0 0 3 3 3 1 Phosphate metabolism protein DUF4463 PF14703.1 AEO58626.1 - 1.2e-09 38.4 0.0 6.2e-09 36.2 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4463) Plasmodium_Vir PF05795.6 AEO58627.1 - 0.037 13.2 0.0 0.04 13.1 0.0 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Pkinase PF00069.20 AEO58628.1 - 0.07 12.2 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain DUF4470 PF14737.1 AEO58629.1 - 1.9e-19 69.2 0.0 4.5e-19 68.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 AEO58629.1 - 2.3e-09 36.9 12.1 5.5e-09 35.7 8.4 1.7 1 0 0 1 1 1 1 MYND finger BTB PF00651.26 AEO58630.1 - 4.6e-15 55.5 0.0 9.8e-15 54.5 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Glyco_hydro_43 PF04616.9 AEO58631.1 - 8.1e-33 113.7 0.2 8.4e-31 107.1 0.1 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 AbfB PF05270.8 AEO58631.1 - 4.7e-08 32.8 0.2 0.001 18.7 0.2 2.5 1 1 1 2 2 2 2 Alpha-L-arabinofuranosidase B (ABFB) TPP_enzyme_N PF02776.13 AEO58632.1 - 7.4e-41 139.4 0.3 2.3e-39 134.6 0.1 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 AEO58632.1 - 7.7e-24 84.0 0.0 1.9e-23 82.7 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 AEO58632.1 - 2e-21 76.1 0.0 2.2e-20 72.8 0.0 2.4 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain Nbs1_C PF08599.5 AEO58632.1 - 0.16 11.8 0.0 0.47 10.4 0.0 1.7 1 0 0 1 1 1 0 DNA damage repair protein Nbs1 Cyclin PF08613.6 AEO58633.1 - 1.7e-40 138.8 0.0 2.7e-40 138.2 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 AEO58633.1 - 0.0028 17.2 0.0 0.0039 16.7 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Pex14_N PF04695.8 AEO58633.1 - 4.8 7.2 10.8 30 4.6 4.8 3.0 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Con-6 PF10346.4 AEO58634.1 - 1.9e-27 94.3 2.1 8.4e-13 47.4 0.1 2.1 2 0 0 2 2 2 2 Conidiation protein 6 Peptidase_M24 PF00557.19 AEO58636.1 - 1.1e-53 181.8 0.0 1.5e-53 181.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 AEO58636.1 - 1.2e-25 89.4 0.0 2.3e-25 88.5 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Peptidase_C97 PF05903.9 AEO58637.1 - 0.0012 18.5 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 AEO58637.1 - 0.27 11.2 0.7 5.7 6.9 0.5 2.2 1 1 0 1 1 1 0 Lecithin retinol acyltransferase DUF4231 PF14015.1 AEO58637.1 - 8.7 6.3 7.9 1.7 8.6 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) GMC_oxred_N PF00732.14 AEO58638.1 - 2.8e-50 171.1 0.0 3.7e-50 170.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 AEO58638.1 - 3.3e-31 108.5 0.1 5.5e-31 107.7 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 AEO58638.1 - 8e-06 24.9 0.1 0.01 14.7 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 AEO58638.1 - 0.00032 19.7 0.0 0.00047 19.1 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 AEO58638.1 - 0.00098 18.0 0.0 0.024 13.5 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 AEO58638.1 - 0.0011 18.9 0.1 0.0052 16.7 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 AEO58638.1 - 0.0037 15.7 0.0 0.092 11.2 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 AEO58638.1 - 0.027 13.3 0.2 1.4 7.7 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 AEO58638.1 - 0.038 13.8 0.1 0.093 12.5 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AEO58638.1 - 0.04 13.9 0.0 0.26 11.3 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ATG22 PF11700.3 AEO58639.1 - 0.00058 18.4 0.6 0.00058 18.4 0.4 1.5 2 0 0 2 2 2 1 Vacuole effluxer Atg22 like SET PF00856.23 AEO58640.1 - 8.4e-05 22.9 0.1 0.00052 20.3 0.0 2.4 2 1 0 2 2 2 1 SET domain T2SE_Nter PF05157.10 AEO58640.1 - 0.01 15.8 0.0 1 9.4 0.0 2.7 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein E, N-terminal domain ArsA_ATPase PF02374.10 AEO58640.1 - 0.049 12.6 0.0 0.077 12.0 0.0 1.3 1 0 0 1 1 1 0 Anion-transporting ATPase CDC45 PF02724.9 AEO58641.1 - 1 7.3 7.7 1.3 7.0 5.4 1.1 1 0 0 1 1 1 0 CDC45-like protein SNARE_assoc PF09335.6 AEO58642.1 - 0.0046 17.1 2.4 0.3 11.3 0.0 2.9 1 1 1 3 3 3 2 SNARE associated Golgi protein TPR_10 PF13374.1 AEO58643.1 - 2.6e-23 81.1 0.7 6.5e-08 32.2 0.1 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 AEO58643.1 - 3.4e-19 68.5 0.2 1.8e-12 47.0 0.0 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 AEO58643.1 - 2.5e-08 33.4 0.1 0.00026 20.5 0.0 2.2 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 AEO58643.1 - 2.3e-07 30.1 0.1 0.29 10.8 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 AEO58643.1 - 2.4e-07 30.0 0.7 0.84 9.5 0.0 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 AEO58643.1 - 5.6e-07 28.9 0.5 0.36 10.8 0.2 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_4 PF07721.9 AEO58643.1 - 7.1e-07 29.0 1.2 1.3 9.6 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 AEO58643.1 - 9.8e-07 28.5 0.1 1.7 9.0 0.0 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_20 PF14561.1 AEO58643.1 - 2.2e-05 24.5 0.5 0.035 14.2 0.0 2.9 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 AEO58643.1 - 3.2e-05 24.4 1.0 0.19 12.4 0.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 AEO58643.1 - 6.8e-05 23.1 1.0 0.17 12.2 0.0 2.7 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 AEO58643.1 - 0.00019 21.7 4.4 0.11 13.1 0.4 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 AEO58643.1 - 0.00026 21.2 1.2 0.39 11.2 0.0 3.5 4 0 0 4 4 3 1 Tetratricopeptide repeat PPR_3 PF13812.1 AEO58643.1 - 0.0016 18.6 0.3 0.74 10.2 0.1 3.2 3 0 0 3 3 3 1 Pentatricopeptide repeat domain PPR PF01535.15 AEO58643.1 - 0.036 14.0 0.9 0.76 9.8 0.1 2.9 3 0 0 3 3 3 0 PPR repeat TPR_21 PF09976.4 AEO58643.1 - 0.05 13.5 0.4 0.9 9.4 0.0 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 AEO58643.1 - 0.094 12.5 0.4 20 5.2 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.20 AEO58644.1 - 2.9e-09 36.4 0.0 5.3e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 AEO58644.1 - 0.0021 17.8 0.0 0.0089 15.7 0.0 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 AEO58644.1 - 0.019 14.0 0.0 0.039 13.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 AEO58644.1 - 0.083 11.9 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase PBP_like_2 PF12849.2 AEO58645.1 - 5.7e-10 39.1 3.9 7.7e-10 38.6 2.7 1.2 1 0 0 1 1 1 1 PBP superfamily domain SBP_bac_11 PF13531.1 AEO58645.1 - 0.00018 21.2 1.0 0.0034 17.0 0.7 2.2 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.20 AEO58645.1 - 0.006 16.3 0.9 0.021 14.5 0.1 2.1 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein MFS_1 PF07690.11 AEO58646.1 - 1.1e-05 24.2 2.8 1.1e-05 24.2 1.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO58646.1 - 0.0016 17.0 0.3 0.0017 16.9 0.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Nuc_deoxyrib_tr PF05014.10 AEO58647.1 - 0.083 12.7 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase Sushi PF00084.15 AEO58647.1 - 0.12 12.7 0.2 0.28 11.5 0.1 1.5 1 0 0 1 1 1 0 Sushi domain (SCR repeat) tRNA-synt_1e PF01406.14 AEO58648.1 - 1.1e-113 379.4 0.0 1.6e-113 378.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 AEO58648.1 - 8.4e-06 24.6 0.3 0.091 11.3 0.0 3.0 3 0 0 3 3 3 2 tRNA synthetases class I (M) DALR_2 PF09190.6 AEO58648.1 - 8e-05 22.8 0.1 0.00026 21.1 0.0 1.9 1 0 0 1 1 1 1 DALR domain tRNA-synt_1f PF01921.13 AEO58648.1 - 0.029 13.0 0.1 5.3 5.6 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (K) PAN_4 PF14295.1 AEO58649.1 - 5.9e-08 32.3 0.6 9.9e-08 31.5 0.4 1.4 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.7 AEO58649.1 - 0.09 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 PAN-like domain 4HBT PF03061.17 AEO58650.1 - 1e-15 57.5 0.2 2.2e-15 56.5 0.1 1.5 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.1 AEO58650.1 - 0.0022 18.4 0.0 0.0025 18.2 0.0 1.3 1 1 0 1 1 1 1 Thioesterase-like superfamily DUF4442 PF14539.1 AEO58650.1 - 0.023 14.6 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) Kelch_3 PF13415.1 AEO58651.1 - 4.7e-07 29.7 2.0 0.00029 20.9 0.0 3.0 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_4 PF13418.1 AEO58651.1 - 2.4e-05 24.0 0.0 0.093 12.5 0.0 3.3 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 AEO58651.1 - 6.4e-05 22.9 0.2 0.039 14.1 0.0 3.2 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.1 AEO58651.1 - 0.31 11.0 1.9 0.75 9.8 0.0 2.6 3 0 0 3 3 3 0 Kelch motif MR_MLE PF01188.16 AEO58653.1 - 2.7e-14 53.4 0.0 8.6e-14 51.8 0.0 1.9 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_C PF13378.1 AEO58653.1 - 3e-13 49.7 0.0 7.5e-13 48.4 0.0 1.7 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 AEO58653.1 - 0.00026 20.9 0.0 0.00056 19.8 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Zn_clus PF00172.13 AEO58654.1 - 9.4e-10 38.2 8.7 1.6e-09 37.5 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 AEO58654.1 - 1.9e-09 36.7 6.7 4.8e-09 35.4 4.6 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 AEO58655.1 - 1.6e-80 270.8 6.0 1.9e-80 270.6 4.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO58655.1 - 3.1e-26 91.9 8.7 4.2e-26 91.4 6.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 AEO58655.1 - 6e-08 31.5 2.7 0.0021 16.5 0.0 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_3 PF05977.8 AEO58655.1 - 0.011 13.9 3.4 0.029 12.5 0.1 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector Epimerase PF01370.16 AEO58656.1 - 1.9e-05 24.2 0.4 0.00027 20.4 0.3 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 AEO58656.1 - 0.00085 18.1 0.0 0.0013 17.4 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family WD40 PF00400.27 AEO58658.1 - 4.7e-54 178.4 18.1 7.1e-09 35.2 0.0 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 AEO58658.1 - 5.1e-12 45.3 0.4 1.1e-11 44.2 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 AEO58658.1 - 4e-11 42.2 0.7 1.4e-10 40.5 0.4 2.0 1 1 0 1 1 1 1 F-box domain PQQ_2 PF13360.1 AEO58658.1 - 0.00029 20.3 0.5 1.5 8.1 0.0 3.2 2 1 1 3 3 3 3 PQQ-like domain Nup160 PF11715.3 AEO58658.1 - 0.00092 17.4 9.4 2.5 6.1 0.0 5.0 2 2 2 5 5 5 4 Nucleoporin Nup120/160 CPSF_A PF03178.10 AEO58658.1 - 0.084 11.9 0.1 0.37 9.8 0.0 2.0 3 0 0 3 3 3 0 CPSF A subunit region PRANC PF09372.5 AEO58658.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 PRANC domain UMPH-1 PF05822.7 AEO58658.1 - 0.31 10.3 0.0 0.62 9.3 0.0 1.4 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) PAP2 PF01569.16 AEO58659.1 - 6.1e-24 84.1 2.3 3.2e-23 81.8 0.2 2.1 2 0 0 2 2 2 1 PAP2 superfamily FtsX PF02687.16 AEO58659.1 - 0.029 14.1 2.4 3.2 7.5 0.2 2.8 3 0 0 3 3 3 0 FtsX-like permease family YhhN PF07947.9 AEO58659.1 - 0.073 12.4 2.7 1.2 8.5 0.0 2.5 3 0 0 3 3 3 0 YhhN-like protein Proteasome PF00227.21 AEO58660.1 - 5e-61 205.3 0.1 6.2e-61 204.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 AEO58660.1 - 1.7e-14 52.7 0.4 4.1e-14 51.5 0.2 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Nitrate_red_gam PF02665.9 AEO58660.1 - 0.16 11.2 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit TFIIS_M PF07500.9 AEO58661.1 - 7.9e-19 67.8 0.1 1.7e-18 66.7 0.1 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.8 AEO58661.1 - 9.1e-19 68.0 0.0 1.8e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 SPOC domain PHD PF00628.24 AEO58661.1 - 1.7e-09 37.2 8.0 3.4e-09 36.2 5.5 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 AEO58661.1 - 0.43 9.9 2.4 0.76 9.1 1.7 1.4 1 0 0 1 1 1 0 PHD-finger Med7 PF05983.6 AEO58662.1 - 1.5e-47 161.4 0.0 1.9e-47 161.0 0.0 1.1 1 0 0 1 1 1 1 MED7 protein RPW8 PF05659.6 AEO58662.1 - 0.045 13.2 0.0 0.75 9.3 0.0 2.0 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 zf-C2H2_jaz PF12171.3 AEO58663.1 - 0.007 16.4 0.1 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 AEO58663.1 - 0.055 13.5 0.1 0.092 12.8 0.1 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Fzo_mitofusin PF04799.8 AEO58663.1 - 0.58 9.5 1.5 0.89 8.9 1.1 1.2 1 0 0 1 1 1 0 fzo-like conserved region RPEL PF02755.10 AEO58664.1 - 5.6e-08 31.8 0.1 0.00012 21.3 0.0 2.6 2 0 0 2 2 2 2 RPEL repeat zf-3CxxC PF13695.1 AEO58665.1 - 0.027 14.6 7.2 0.03 14.5 5.0 1.1 1 0 0 1 1 1 0 Zinc-binding domain Lipocalin PF00061.18 AEO58665.1 - 0.084 12.8 0.1 0.098 12.6 0.0 1.1 1 0 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family zf-C4pol PF14260.1 AEO58665.1 - 0.17 11.8 4.7 3.7 7.6 0.6 2.2 1 1 1 2 2 2 0 C4-type zinc-finger of DNA polymerase delta Endonuc_Holl PF10107.4 AEO58665.1 - 0.35 10.5 2.3 0.42 10.3 1.6 1.1 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Zn_ribbon_recom PF13408.1 AEO58665.1 - 0.46 10.7 7.2 3.1 8.1 1.2 2.2 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain LAMTOR PF15454.1 AEO58666.1 - 9.8e-17 61.0 0.2 1.8e-16 60.1 0.1 1.4 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator ER-remodelling PF14755.1 AEO58667.1 - 0.14 12.2 0.3 0.16 12.0 0.2 1.1 1 0 0 1 1 1 0 Intracellular membrane remodeller SKG6 PF08693.5 AEO58668.1 - 1.3e-05 24.4 1.9 1.3e-05 24.4 1.3 2.3 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 AEO58668.1 - 0.00077 18.9 0.1 0.0012 18.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Dynamin_N PF00350.18 AEO58670.1 - 2.4e-23 82.7 0.0 2.5e-22 79.4 0.0 2.4 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 AEO58670.1 - 4.4e-08 32.2 0.1 9.5e-08 31.1 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region GED PF02212.13 AEO58670.1 - 0.0005 19.9 0.0 0.0013 18.6 0.0 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 AEO58670.1 - 0.0016 18.3 0.0 0.034 14.1 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.1 AEO58670.1 - 0.0064 16.4 0.1 0.028 14.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 AEO58670.1 - 0.017 15.6 0.0 0.052 14.0 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein AAA_29 PF13555.1 AEO58670.1 - 0.027 13.9 0.1 0.063 12.8 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PduV-EutP PF10662.4 AEO58670.1 - 0.042 13.3 0.0 4.4 6.7 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 AEO58670.1 - 0.042 14.1 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 ABC transporter NTP_transferase PF00483.18 AEO58671.1 - 1.4e-29 103.1 0.0 2.1e-29 102.5 0.0 1.4 1 1 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 AEO58671.1 - 5e-11 41.5 6.3 9.3e-06 24.9 0.0 3.6 4 0 0 4 4 4 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 AEO58671.1 - 6.1e-07 29.6 0.0 9.1e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.14 AEO58671.1 - 0.014 14.9 0.0 0.033 13.7 0.0 1.6 2 0 0 2 2 2 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Fucokinase PF07959.7 AEO58671.1 - 0.026 13.0 0.0 0.61 8.5 0.0 2.2 2 0 0 2 2 2 0 L-fucokinase CDC45 PF02724.9 AEO58672.1 - 0.0097 13.9 2.1 0.011 13.8 1.4 1.1 1 0 0 1 1 1 1 CDC45-like protein FLO_LFY PF01698.11 AEO58672.1 - 0.07 11.9 4.9 0.11 11.3 3.4 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein Hid1 PF12722.2 AEO58672.1 - 0.43 8.1 2.6 0.58 7.7 1.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2201_N PF13203.1 AEO58672.1 - 0.56 9.3 9.4 0.85 8.7 6.5 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF4407 PF14362.1 AEO58672.1 - 2 7.3 14.7 2.9 6.7 10.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) COPI_C PF06957.6 AEO58672.1 - 8.4 4.7 9.8 12 4.2 6.8 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Glyco_hydro_31 PF01055.21 AEO58673.1 - 2.5e-128 428.6 0.2 3e-128 428.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 AEO58673.1 - 1.9e-05 24.4 0.1 9.3e-05 22.2 0.0 2.2 2 1 0 2 2 2 1 Galactose mutarotase-like Glycos_transf_1 PF00534.15 AEO58675.1 - 1.4e-09 37.5 0.0 5.2e-09 35.7 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 AEO58675.1 - 6.6e-08 32.7 0.0 1.2e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Metallopep PF12044.3 AEO58676.1 - 5.7e-103 344.6 0.0 1.1e-102 343.6 0.0 1.4 1 1 0 1 1 1 1 Putative peptidase family Asp PF00026.18 AEO58677.1 - 5e-58 196.8 0.0 6e-58 196.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 AEO58677.1 - 7.7e-07 29.1 0.0 4e-06 26.8 0.0 2.2 3 0 0 3 3 3 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 AEO58677.1 - 9.3e-06 25.2 0.0 0.00023 20.7 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 AEO58677.1 - 0.003 18.0 0.1 0.15 12.5 0.0 3.2 2 1 0 2 2 2 1 Aspartyl protease APH PF01636.18 AEO58678.1 - 2.5e-06 27.4 0.0 3.6e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 AEO58678.1 - 8.5e-05 22.2 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 AEO58678.1 - 0.018 14.2 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Glyco_hydro_18 PF00704.23 AEO58679.1 - 3.8e-51 174.5 0.6 5.4e-51 174.0 0.1 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 LysM PF01476.15 AEO58679.1 - 3.2e-08 33.3 0.2 0.011 15.6 0.0 3.5 3 0 0 3 3 3 2 LysM domain Chitin_bind_1 PF00187.14 AEO58679.1 - 8.8e-05 22.4 3.7 8.8e-05 22.4 2.6 2.6 2 0 0 2 2 2 1 Chitin recognition protein DUF3142 PF11340.3 AEO58679.1 - 0.00022 20.9 0.0 0.00039 20.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3142) PhageP22-tail PF09251.5 AEO58681.1 - 0.044 12.0 0.4 0.083 11.1 0.1 1.5 2 0 0 2 2 2 0 Salmonella phage P22 tail-spike Asparaginase_2 PF01112.13 AEO58685.1 - 2.7e-42 144.6 5.2 1.8e-19 69.6 0.2 3.4 2 1 0 3 3 3 3 Asparaginase Peptidase_M20 PF01546.23 AEO58687.1 - 7.6e-23 80.9 0.0 1.6e-22 79.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.27 AEO58687.1 - 2e-18 65.4 5.3 0.00016 21.4 0.0 5.9 5 0 0 5 5 5 3 WD domain, G-beta repeat M20_dimer PF07687.9 AEO58687.1 - 1.1e-10 41.1 0.0 2.4e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF3639 PF12341.3 AEO58687.1 - 0.022 14.7 0.1 0.043 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3639) Peptidase_M28 PF04389.12 AEO58687.1 - 0.06 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M28 CNH PF00780.17 AEO58687.1 - 0.2 11.0 0.0 0.37 10.1 0.0 1.4 1 0 0 1 1 1 0 CNH domain Nucleoporin_N PF08801.6 AEO58687.1 - 0.4 9.3 1.7 25 3.4 0.0 2.9 2 2 1 3 3 3 0 Nup133 N terminal like MatE PF01554.13 AEO58690.1 - 0.00016 21.3 17.1 0.029 13.9 1.5 3.4 2 1 0 2 2 2 2 MatE TauD PF02668.11 AEO58691.1 - 2.7e-43 148.5 0.3 3.3e-43 148.2 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TAT_signal PF10518.4 AEO58691.1 - 0.17 11.9 2.8 0.42 10.7 1.9 1.7 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence Carb_anhydrase PF00194.16 AEO58693.1 - 1.8e-15 56.6 0.0 6.8e-08 31.7 0.0 2.4 2 1 0 2 2 2 2 Eukaryotic-type carbonic anhydrase Myb_DNA-binding PF00249.26 AEO58694.1 - 3.7e-24 84.4 0.2 3.8e-13 49.2 0.1 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 AEO58694.1 - 6.1e-22 77.4 0.3 4.1e-14 52.4 0.1 2.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 AEO58694.1 - 0.046 13.6 0.6 9.7 6.1 0.1 3.4 3 1 1 4 4 4 0 Myb/SANT-like DNA-binding domain Tombus_movement PF05318.7 AEO58694.1 - 0.076 13.6 0.4 1 10.0 0.0 2.1 2 0 0 2 2 2 0 Tombusvirus movement protein MFS_1 PF07690.11 AEO58695.1 - 3.3e-24 85.2 51.6 3.3e-24 85.2 35.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Transferase PF02458.10 AEO58696.1 - 1.1e-18 66.8 0.0 1.1e-16 60.3 0.0 2.9 2 1 0 2 2 2 2 Transferase family ketoacyl-synt PF00109.21 AEO58697.1 - 2.6e-71 240.0 0.1 5.5e-71 239.0 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 AEO58697.1 - 6.4e-52 176.8 0.0 1.2e-51 175.9 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 AEO58697.1 - 9.4e-51 172.7 0.0 2.8e-50 171.1 0.0 1.9 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 AEO58697.1 - 2.9e-48 163.9 0.7 1.2e-47 161.9 0.5 2.2 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 AEO58697.1 - 1e-41 142.6 0.9 3.2e-41 141.0 0.6 1.9 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 AEO58697.1 - 9.8e-37 125.4 0.2 3.2e-36 123.7 0.0 2.0 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 AEO58697.1 - 1.3e-13 51.2 1.3 4.6e-13 49.4 0.9 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO58697.1 - 3.1e-13 49.7 0.0 8.2e-13 48.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO58697.1 - 5.8e-07 29.9 0.2 2.6e-06 27.8 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO58697.1 - 1.7e-06 28.5 0.5 7.7e-06 26.4 0.0 2.5 2 0 0 2 2 1 1 Methyltransferase domain PP-binding PF00550.20 AEO58697.1 - 5.2e-05 23.4 0.0 0.00013 22.1 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.1 AEO58697.1 - 9e-05 22.1 0.0 0.0011 18.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Thiolase_N PF00108.18 AEO58697.1 - 0.00038 19.5 0.3 0.00072 18.6 0.2 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_24 PF13578.1 AEO58697.1 - 0.026 15.3 0.0 0.31 11.9 0.0 2.7 2 0 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.13 AEO58697.1 - 0.027 13.5 0.0 0.088 11.9 0.0 1.7 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family RrnaAD PF00398.15 AEO58697.1 - 0.035 13.1 0.0 0.077 12.0 0.0 1.5 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.1 AEO58697.1 - 0.13 12.6 0.0 0.33 11.3 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Shikimate_DH PF01488.15 AEO58697.1 - 0.2 11.7 0.0 0.55 10.3 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Phostensin PF13914.1 AEO58697.1 - 0.4 10.7 0.9 10 6.2 0.1 2.9 3 0 0 3 3 2 0 Phostensin PP1-binding and SH3-binding region Methyltransf_16 PF10294.4 AEO58697.1 - 0.41 10.0 0.1 5.7 6.3 0.1 2.2 1 1 0 1 1 1 0 Putative methyltransferase GCD14 PF08704.5 AEO58697.1 - 0.76 9.2 0.0 1.8 8.0 0.0 1.5 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit CMAS PF02353.15 AEO58697.1 - 1.4 7.9 0.0 2.8 6.9 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Epimerase PF01370.16 AEO58698.1 - 1.2e-57 195.1 0.0 1.6e-57 194.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 AEO58698.1 - 2e-21 76.1 0.0 7.5e-21 74.2 0.0 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 AEO58698.1 - 1.3e-20 73.3 0.0 1.7e-20 72.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 AEO58698.1 - 2.3e-18 66.0 0.1 7.8e-17 61.0 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 AEO58698.1 - 2.9e-18 65.7 0.0 3.7e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 AEO58698.1 - 3.3e-10 40.2 0.0 5.3e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 AEO58698.1 - 6.7e-06 26.1 0.9 8.3e-06 25.8 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 AEO58698.1 - 0.0018 17.9 0.0 0.0029 17.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 AEO58699.1 - 6.4e-11 42.1 0.0 1e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 AEO58699.1 - 3.3e-09 36.0 0.0 4.5e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 AEO58699.1 - 0.041 12.7 0.0 0.11 11.4 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 AEO58699.1 - 0.042 12.7 0.0 0.064 12.1 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein zf-BED PF02892.10 AEO58701.1 - 0.0018 17.9 0.2 0.0029 17.3 0.1 1.3 1 0 0 1 1 1 1 BED zinc finger zf-C2H2 PF00096.21 AEO58701.1 - 0.0033 17.6 2.6 0.0033 17.6 1.8 2.0 2 0 0 2 2 2 1 Zinc finger, C2H2 type DUF629 PF04780.7 AEO58701.1 - 0.01 14.4 0.2 0.014 13.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF629) zf-C2H2_6 PF13912.1 AEO58701.1 - 0.023 14.5 1.1 0.037 13.9 0.8 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_4 PF13894.1 AEO58701.1 - 0.032 14.5 1.4 0.032 14.5 1.0 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 AEO58701.1 - 0.091 12.8 0.1 0.19 11.8 0.1 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 AEO58701.1 - 0.22 11.7 0.1 0.22 11.7 0.1 2.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 AEO58701.1 - 2.7 8.2 5.4 0.65 10.2 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding PepSY_TM_2 PF13703.1 AEO58703.1 - 0.034 14.3 1.1 0.73 10.0 0.0 2.6 2 1 0 2 2 2 0 PepSY-associated TM helix ArsB PF02040.10 AEO58704.1 - 1e-13 51.0 21.0 1.1e-09 37.8 5.6 2.3 2 0 0 2 2 2 2 Arsenical pump membrane protein F-box-like PF12937.2 AEO58705.1 - 0.008 15.8 0.0 0.031 13.9 0.0 2.1 2 1 0 2 2 2 1 F-box-like NAD_binding_10 PF13460.1 AEO58706.1 - 2.8e-13 50.2 1.7 4.2e-13 49.6 1.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 AEO58706.1 - 1.4e-09 37.5 0.0 1.9e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 AEO58706.1 - 5.3e-05 22.7 0.0 0.0036 16.7 0.0 2.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 AEO58706.1 - 0.00011 22.2 1.1 0.00011 22.2 0.7 2.7 2 1 1 3 3 3 1 short chain dehydrogenase KR PF08659.5 AEO58706.1 - 0.0083 15.8 0.6 0.027 14.1 0.2 2.0 1 1 1 2 2 2 1 KR domain adh_short_C2 PF13561.1 AEO58706.1 - 0.065 12.9 0.0 0.095 12.4 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Saccharop_dh PF03435.13 AEO58706.1 - 0.077 11.9 0.1 0.097 11.6 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Phytase-like PF13449.1 AEO58707.1 - 4e-28 98.6 0.4 1.1e-27 97.2 0.1 1.9 2 1 0 2 2 2 1 Esterase-like activity of phytase zf-U1 PF06220.7 AEO58709.1 - 2.2e-07 30.2 0.2 3.4e-07 29.7 0.2 1.3 1 0 0 1 1 1 1 U1 zinc finger BLOC1_2 PF10046.4 AEO58709.1 - 0.036 14.2 0.0 0.068 13.3 0.0 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Ank_2 PF12796.2 AEO58710.1 - 2.1e-21 76.0 0.0 4.5e-12 46.1 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 AEO58710.1 - 2.7e-21 74.2 0.8 1.1e-05 24.9 0.1 5.0 4 1 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.1 AEO58710.1 - 8.1e-19 65.8 0.1 0.00023 21.1 0.0 4.9 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 AEO58710.1 - 2.7e-16 59.5 0.3 0.00014 22.2 0.0 4.0 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 AEO58710.1 - 5.4e-11 42.3 2.3 0.012 15.7 0.0 4.6 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Cutinase PF01083.17 AEO58711.1 - 4e-53 179.8 0.1 4.9e-53 179.4 0.1 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 AEO58711.1 - 9.3e-05 21.9 0.1 0.00014 21.3 0.1 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_5 PF12695.2 AEO58711.1 - 0.004 16.9 0.6 0.011 15.4 0.4 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AEO58711.1 - 0.063 13.1 0.1 0.063 13.1 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family RVT_1 PF00078.22 AEO58712.1 - 5.7e-05 22.5 1.2 5.7e-05 22.5 0.8 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) p450 PF00067.17 AEO58713.1 - 7e-44 150.1 0.0 9e-44 149.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cupin_2 PF07883.6 AEO58714.1 - 1.2e-06 27.9 0.0 2.6e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 AEO58714.1 - 0.00076 18.8 0.0 0.0043 16.3 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF861) Cupin_6 PF12852.2 AEO58714.1 - 0.0013 18.3 0.3 0.0021 17.7 0.2 1.3 1 0 0 1 1 1 1 Cupin ASFV_J13L PF05568.6 AEO58714.1 - 0.25 10.8 1.4 0.37 10.2 1.0 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein Lactamase_B_2 PF12706.2 AEO58716.1 - 1.3e-21 77.0 9.6 2.1e-21 76.3 5.7 1.9 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 AEO58716.1 - 2.1e-05 24.2 5.5 0.024 14.2 0.1 2.7 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.1 AEO58716.1 - 0.00026 20.7 2.9 0.00051 19.7 2.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Sigma70_ner PF04546.8 AEO58716.1 - 0.073 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 AEO58716.1 - 0.076 12.5 2.7 0.14 11.6 1.9 1.4 1 0 0 1 1 1 0 Nucleoplasmin Macoilin PF09726.4 AEO58716.1 - 2.3 6.3 3.8 3.1 5.9 2.7 1.1 1 0 0 1 1 1 0 Transmembrane protein CPSF73-100_C PF11718.3 AEO58716.1 - 3.2 7.0 8.0 5.4 6.3 5.5 1.3 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term p450 PF00067.17 AEO58717.1 - 6.3e-61 206.2 0.0 8.3e-61 205.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Band_7 PF01145.20 AEO58718.1 - 3.6e-31 108.4 0.6 3.6e-31 108.4 0.4 1.6 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 AEO58718.1 - 0.032 13.7 0.0 0.056 12.9 0.0 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family Sec7_N PF12783.2 AEO58719.1 - 6.4e-32 110.3 2.4 4.5e-31 107.5 0.0 3.2 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 AEO58719.1 - 6.4e-07 28.7 0.4 4.6e-05 22.8 0.0 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) UQ_con PF00179.21 AEO58720.1 - 9.9e-13 47.7 0.0 1.1e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 AEO58720.1 - 0.0016 18.3 0.0 0.0018 18.1 0.0 1.3 1 0 0 1 1 1 1 RWD domain Complex1_LYR PF05347.10 AEO58721.1 - 6.6e-12 45.0 0.0 1.6e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 AEO58721.1 - 5.7e-11 42.4 0.2 2.6e-10 40.3 0.0 2.2 2 0 0 2 2 2 1 Complex1_LYR-like GatB_Yqey PF02637.13 AEO58721.1 - 0.041 13.6 0.1 0.088 12.5 0.1 1.5 1 0 0 1 1 1 0 GatB domain Pkinase PF00069.20 AEO58723.1 - 1e-29 103.4 1.7 2.9e-28 98.7 0.0 2.7 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO58723.1 - 5.6e-21 74.7 0.1 1.4e-20 73.4 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase CALCOCO1 PF07888.6 AEO58723.1 - 0.015 13.6 5.0 0.022 13.0 3.5 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like V_ATPase_I PF01496.14 AEO58723.1 - 0.072 10.9 3.8 0.097 10.5 2.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APH PF01636.18 AEO58723.1 - 0.18 11.5 3.5 1.5 8.5 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF3972 PF13118.1 AEO58723.1 - 0.19 11.7 3.1 0.36 10.9 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) TMF_TATA_bd PF12325.3 AEO58723.1 - 1.1 8.9 11.8 0.8 9.4 5.5 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding IncA PF04156.9 AEO58723.1 - 5.3 6.5 9.5 9.9 5.7 6.6 1.4 1 0 0 1 1 1 0 IncA protein DUF3437 PF11919.3 AEO58724.1 - 8.2e-32 108.7 0.2 4e-31 106.5 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) HEAT PF02985.17 AEO58724.1 - 0.0059 16.5 3.5 8.7 6.7 0.0 5.3 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.1 AEO58724.1 - 0.12 12.6 2.9 5.7 7.2 0.0 5.0 6 1 0 6 6 6 0 HEAT repeats IncA PF04156.9 AEO58725.1 - 0.074 12.6 0.2 0.11 12.0 0.2 1.2 1 0 0 1 1 1 0 IncA protein Striatin PF08232.7 AEO58725.1 - 0.092 13.0 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 Striatin family Atg14 PF10186.4 AEO58725.1 - 0.1 11.5 0.9 0.14 11.0 0.6 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF836 PF05768.9 AEO58725.1 - 0.13 12.5 0.6 2.7 8.3 0.1 2.7 3 0 0 3 3 3 0 Glutaredoxin-like domain (DUF836) MscS_porin PF12795.2 AEO58725.1 - 0.14 11.4 5.4 0.2 10.9 3.8 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain REV PF00424.13 AEO58725.1 - 0.14 12.0 2.8 0.26 11.1 1.9 1.4 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) Reo_sigmaC PF04582.7 AEO58725.1 - 0.15 11.2 0.0 0.2 10.7 0.0 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein HXXSHH PF07586.6 AEO58725.1 - 0.18 10.6 1.1 0.33 9.8 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) Sugarporin_N PF11471.3 AEO58725.1 - 0.43 10.2 3.1 0.29 10.8 0.3 2.0 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension CASP_C PF08172.7 AEO58725.1 - 0.59 9.1 3.3 0.95 8.4 2.3 1.3 1 0 0 1 1 1 0 CASP C terminal Methyltransf_31 PF13847.1 AEO58726.1 - 2e-23 82.6 0.0 2.9e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO58726.1 - 6.9e-16 58.5 0.0 1.1e-15 57.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO58726.1 - 1.2e-12 48.0 0.0 2.4e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AEO58726.1 - 1.6e-12 47.0 0.0 2.4e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 AEO58726.1 - 2.5e-11 44.1 0.0 4.7e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO58726.1 - 3.5e-11 43.0 0.0 5.3e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO58726.1 - 1.5e-10 41.4 0.0 2.2e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO58726.1 - 7.8e-09 35.5 0.1 1.3e-08 34.8 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 AEO58726.1 - 8.3e-07 28.7 0.0 1e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 AEO58726.1 - 0.00031 20.1 0.0 0.00049 19.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 AEO58726.1 - 0.0017 17.5 0.1 0.0022 17.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 AEO58726.1 - 0.0021 17.1 0.0 0.0027 16.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 AEO58726.1 - 0.0083 15.8 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Tyrosinase PF00264.15 AEO58727.1 - 3.8e-31 108.9 4.6 7.5e-31 108.0 3.2 1.4 1 1 0 1 1 1 1 Common central domain of tyrosinase DUF619 PF04768.8 AEO58727.1 - 0.11 11.8 0.5 0.17 11.2 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF619) Cyclin_N PF00134.18 AEO58728.1 - 1.1e-14 54.0 0.0 3.2e-14 52.5 0.0 1.8 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 AEO58728.1 - 3.8e-11 43.5 0.0 8.7e-11 42.4 0.0 1.6 1 1 0 1 1 1 1 Cyclin Pkinase PF00069.20 AEO58730.1 - 2.2e-72 243.3 0.0 2.6e-72 243.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO58730.1 - 2.6e-31 108.6 0.0 3.3e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO58730.1 - 0.0019 17.2 0.0 0.003 16.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AEO58730.1 - 0.005 16.6 0.1 0.014 15.0 0.0 1.6 1 1 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 AEO58730.1 - 0.017 13.9 0.0 0.025 13.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.4 AEO58730.1 - 0.14 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.9 AEO58730.1 - 0.15 11.0 0.1 0.48 9.4 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family 2OG-FeII_Oxy_2 PF13532.1 AEO58731.1 - 1.7e-29 103.0 0.0 3.1e-29 102.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 AEO58731.1 - 0.00015 22.2 0.0 0.00043 20.7 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF605 PF04652.11 AEO58732.1 - 0.0059 16.0 0.4 0.0059 16.0 0.3 1.1 1 0 0 1 1 1 1 Vta1 like Myb_DNA-bind_2 PF08914.6 AEO58733.1 - 1.6e-28 98.2 7.3 8.7e-14 51.0 0.2 3.5 4 0 0 4 4 4 2 Rap1 Myb domain Rap1_C PF11626.3 AEO58733.1 - 1.9e-24 85.3 0.0 1.7e-22 79.1 0.0 2.5 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Rap1-DNA-bind PF09197.5 AEO58733.1 - 3e-09 37.3 3.6 0.0011 19.4 0.0 3.7 4 0 0 4 4 4 2 Rap1, DNA-binding ARID PF01388.16 AEO58733.1 - 0.0045 16.8 0.0 0.013 15.3 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Myb_DNA-bind_6 PF13921.1 AEO58733.1 - 0.013 15.5 3.9 1.4 9.0 0.0 4.1 4 0 0 4 4 4 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 AEO58733.1 - 0.28 11.2 6.0 3.9 7.5 0.0 4.2 5 0 0 5 5 5 0 Myb-like DNA-binding domain IQ PF00612.22 AEO58733.1 - 0.42 10.3 12.3 1.4 8.7 3.5 2.6 2 0 0 2 2 2 0 IQ calmodulin-binding motif zf-DHHC PF01529.15 AEO58734.1 - 3.2e-33 114.5 0.0 5.3e-33 113.8 0.0 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase MMR_HSR1 PF01926.18 AEO58735.1 - 5.7e-18 64.9 0.0 1e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 AEO58735.1 - 3.5e-09 36.3 0.0 9.5e-09 34.9 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 AEO58735.1 - 5.7e-06 25.6 0.0 0.0012 18.1 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 AEO58735.1 - 9.1e-06 25.5 0.0 2.2e-05 24.3 0.0 1.6 1 1 0 1 1 1 1 Dynamin family DUF258 PF03193.11 AEO58735.1 - 0.0007 18.8 0.0 0.001 18.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 AEO58735.1 - 0.0025 17.2 0.0 0.0049 16.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain IIGP PF05049.8 AEO58735.1 - 0.0081 15.0 0.0 1.1 8.0 0.0 2.1 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) AAA_22 PF13401.1 AEO58735.1 - 0.01 15.9 0.3 0.2 11.8 0.2 2.4 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 AEO58735.1 - 0.013 15.7 0.0 0.029 14.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 AEO58735.1 - 0.025 14.5 0.7 0.08 12.9 0.4 2.0 2 1 0 2 2 1 0 AAA ATPase domain Miro PF08477.8 AEO58735.1 - 0.026 14.9 0.0 0.052 14.0 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein Septin PF00735.13 AEO58735.1 - 0.046 12.7 0.0 0.078 11.9 0.0 1.5 1 1 0 1 1 1 0 Septin MobB PF03205.9 AEO58735.1 - 0.056 13.1 0.1 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AIG1 PF04548.11 AEO58735.1 - 0.08 12.0 0.2 1.2 8.2 0.1 2.1 2 0 0 2 2 2 0 AIG1 family AAA_21 PF13304.1 AEO58735.1 - 0.098 12.6 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 AEO58735.1 - 0.15 12.8 0.8 0.44 11.3 0.1 2.0 2 0 0 2 2 2 0 AAA domain Complex1_LYR_2 PF13233.1 AEO58736.1 - 7.2e-20 71.4 0.0 8.8e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 AEO58736.1 - 0.0028 17.3 1.0 0.0067 16.2 0.7 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 AEO58736.1 - 0.098 12.8 0.3 0.15 12.2 0.2 1.4 1 0 0 1 1 1 0 Complex1_LYR-like Dicty_REP PF05086.7 AEO58736.1 - 0.13 10.0 0.1 0.12 10.1 0.1 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SSP160 PF06933.6 AEO58736.1 - 2.4 6.0 6.2 2.9 5.7 4.3 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Med22 PF06179.7 AEO58737.1 - 0.0015 18.5 1.1 0.091 12.7 0.0 2.5 2 0 0 2 2 2 2 Surfeit locus protein 5 subunit 22 of Mediator complex Aha1_N PF09229.6 AEO58738.1 - 8.5e-37 126.0 0.3 1.4e-36 125.2 0.2 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 AEO58738.1 - 4.3e-20 72.0 1.2 6.9e-20 71.3 0.4 1.7 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.4 AEO58738.1 - 0.0041 17.2 2.1 0.0088 16.2 0.5 2.0 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport Pox_A12 PF04651.8 AEO58738.1 - 0.0043 17.2 0.0 0.0068 16.5 0.0 1.2 1 0 0 1 1 1 1 Poxvirus A12 protein Pec_lyase_C PF00544.14 AEO58739.1 - 2.4e-40 138.1 11.4 4.8e-40 137.1 7.9 1.5 1 1 0 1 1 1 1 Pectate lyase Chitin_bind_3 PF03067.10 AEO58740.1 - 2.4e-07 31.2 0.0 3e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Chitin binding domain p450 PF00067.17 AEO58741.1 - 1.7e-61 208.2 0.0 2.1e-61 207.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Patched PF02460.13 AEO58744.1 - 1.5e-72 244.7 14.2 9.2e-72 242.1 9.8 1.9 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.3 AEO58744.1 - 4.7e-49 165.7 8.5 4.7e-49 165.7 5.9 2.6 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Folate_rec PF03024.9 AEO58744.1 - 3.6e-05 23.4 1.8 7.3e-05 22.4 1.2 1.4 1 0 0 1 1 1 1 Folate receptor family MMPL PF03176.10 AEO58744.1 - 0.00015 20.5 9.1 0.00015 20.5 6.3 2.7 3 0 0 3 3 3 2 MMPL family ACR_tran PF00873.14 AEO58744.1 - 5.1 4.3 19.8 0.06 10.7 7.8 2.0 2 0 0 2 2 2 0 AcrB/AcrD/AcrF family Smr PF01713.16 AEO58745.1 - 2e-11 43.9 0.2 4.8e-11 42.6 0.1 1.7 1 0 0 1 1 1 1 Smr domain CUE PF02845.11 AEO58745.1 - 0.0057 16.1 0.0 0.018 14.5 0.0 1.8 2 0 0 2 2 2 1 CUE domain Amidase PF01425.16 AEO58746.1 - 2.3e-83 280.5 0.0 2.8e-83 280.2 0.0 1.0 1 0 0 1 1 1 1 Amidase Zds_C PF08632.5 AEO58748.1 - 1.3e-31 107.7 0.2 2.2e-31 107.0 0.2 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term DUF2433 PF10360.4 AEO58749.1 - 6.2e-53 178.6 0.0 9.8e-53 177.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos_2 PF12850.2 AEO58749.1 - 0.0029 17.4 0.0 0.0076 16.0 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 AEO58749.1 - 0.0047 16.3 0.0 0.011 15.0 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF2360 PF10152.4 AEO58749.1 - 0.042 14.1 15.5 2.5 8.3 10.8 2.5 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF605 PF04652.11 AEO58749.1 - 0.13 11.6 20.1 0.21 10.9 13.9 1.3 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 AEO58749.1 - 7.8 4.6 15.2 12 4.0 10.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ubie_methyltran PF01209.13 AEO58750.1 - 5.1e-70 235.1 0.0 6.2e-43 146.5 0.0 2.1 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 AEO58750.1 - 7.3e-11 42.4 0.0 2.8e-06 27.7 0.0 2.8 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.1 AEO58750.1 - 1.7e-10 40.7 0.0 5.7e-05 22.7 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 AEO58750.1 - 8.9e-10 38.9 0.0 1.8e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO58750.1 - 2.8e-08 33.6 0.0 4.3e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO58750.1 - 4.7e-08 33.3 0.0 1.7e-07 31.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO58750.1 - 2.7e-05 24.7 0.0 5.9e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO58750.1 - 0.00018 21.5 0.2 0.00083 19.3 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AEO58750.1 - 0.027 13.8 0.0 0.7 9.2 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_8 PF05148.10 AEO58750.1 - 0.05 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Hypothetical methyltransferase E1_dh PF00676.15 AEO58751.1 - 2.9e-87 292.1 0.0 3.5e-87 291.8 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 AEO58751.1 - 0.00016 21.3 0.0 0.0015 18.1 0.0 2.3 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 AEO58751.1 - 0.015 14.2 0.0 0.057 12.3 0.0 1.9 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase SGS PF05002.10 AEO58751.1 - 0.22 11.2 1.5 1.2 8.9 0.4 2.4 2 1 0 2 2 2 0 SGS domain HECT PF00632.20 AEO58754.1 - 6.5e-87 291.6 0.0 1.5e-86 290.4 0.0 1.6 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) RRN3 PF05327.6 AEO58754.1 - 0.0058 14.7 7.7 0.011 13.8 5.3 1.4 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 HEAT PF02985.17 AEO58754.1 - 0.02 14.9 0.9 19 5.6 0.0 4.7 4 0 0 4 4 4 0 HEAT repeat Sec3_C PF09763.4 AEO58756.1 - 2.5e-250 832.4 0.0 3.3e-250 832.0 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 AEO58756.1 - 1.1e-30 105.2 0.0 2.1e-30 104.4 0.0 1.5 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C_2 PF15278.1 AEO58756.1 - 0.016 15.3 1.5 0.059 13.5 0.0 2.6 3 0 0 3 3 3 0 Sec3 exocyst complex subunit Vps52 PF04129.7 AEO58756.1 - 1.6 7.1 3.2 0.71 8.3 0.1 1.8 2 0 0 2 2 2 0 Vps52 / Sac2 family TFIIE-A_C-term PF11521.3 AEO58757.1 - 0.085 12.8 7.6 0.12 12.3 0.1 2.4 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha DUF4604 PF15377.1 AEO58757.1 - 0.37 10.9 4.0 0.44 10.7 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) Fe-ADH PF00465.14 AEO58758.1 - 3.7e-103 344.9 0.0 4.7e-103 344.6 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 AEO58758.1 - 4.7e-13 49.0 0.0 1.7e-10 40.6 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.1 AEO58758.1 - 0.0016 17.8 0.4 0.0035 16.7 0.3 1.5 1 1 1 2 2 2 1 Periplasmic binding protein FAD_binding_1 PF00667.15 AEO58759.1 - 5.4e-59 199.2 0.0 8.5e-59 198.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 AEO58759.1 - 1.1e-11 45.2 0.0 6.4e-11 42.7 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain POR PF01558.13 AEO58759.1 - 4.7e-10 39.6 0.0 1.1e-09 38.4 0.0 1.6 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Transketolase_C PF02780.15 AEO58759.1 - 0.05 13.5 1.6 0.077 12.9 0.3 1.9 2 0 0 2 2 2 0 Transketolase, C-terminal domain FAD_binding_6 PF00970.19 AEO58759.1 - 0.084 13.0 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain E1-E2_ATPase PF00122.15 AEO58760.1 - 4.3e-52 176.4 0.3 4.2e-51 173.1 0.0 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 AEO58760.1 - 1.7e-39 136.4 2.0 2.3e-39 136.0 0.4 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 AEO58760.1 - 1.4e-32 111.6 2.0 7.1e-10 38.8 0.4 4.8 4 0 0 4 4 4 4 Heavy-metal-associated domain HAD PF12710.2 AEO58760.1 - 7e-18 65.4 0.0 1.6e-17 64.2 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 AEO58760.1 - 4.5e-05 23.1 0.3 0.00058 19.5 0.4 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 AEO58760.1 - 6.5e-05 23.2 0.0 0.00019 21.6 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Dishevelled PF02377.10 AEO58760.1 - 0.26 11.5 2.5 0.78 9.9 1.7 1.8 1 0 0 1 1 1 0 Dishevelled specific domain zf-C3HC PF07967.8 AEO58761.1 - 1.8e-40 137.8 0.0 9.2e-37 125.8 0.0 2.2 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.5 AEO58761.1 - 9.1e-27 92.7 0.9 3.6e-25 87.6 0.0 2.5 2 0 0 2 2 2 1 Rsm1-like BIR PF00653.16 AEO58761.1 - 0.00011 22.5 0.1 0.0026 18.1 0.1 2.4 2 0 0 2 2 2 1 Inhibitor of Apoptosis domain FtsX PF02687.16 AEO58762.1 - 0.098 12.4 0.1 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 FtsX-like permease family zf-RING_4 PF14570.1 AEO58763.1 - 1.1e-14 53.7 9.2 1.9e-14 52.9 6.4 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.17 AEO58763.1 - 3.3e-09 36.2 0.0 1e-08 34.6 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rtf2 PF04641.7 AEO58763.1 - 1.3e-05 24.5 1.3 1.3e-05 24.5 0.9 4.9 4 2 1 5 5 5 1 Rtf2 RING-finger RRM_6 PF14259.1 AEO58763.1 - 4.1e-05 23.4 0.0 0.00012 21.9 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO58763.1 - 9e-05 22.2 0.0 0.00031 20.5 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 AEO58763.1 - 0.018 14.7 7.0 0.031 13.9 4.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Nup35_RRM_2 PF14605.1 AEO58763.1 - 0.022 14.5 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif SET_assoc PF11767.3 AEO58763.1 - 0.097 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated Complex1_30kDa PF00329.14 AEO58764.1 - 8.6e-37 125.5 0.0 1.4e-36 124.8 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Dioxygenase_C PF00775.16 AEO58765.1 - 4.9e-47 159.5 0.0 6.3e-47 159.1 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 AEO58765.1 - 5.3e-11 42.3 0.0 8.5e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus Lactonase PF10282.4 AEO58767.1 - 2.6e-15 56.3 0.0 3.7e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Inositol_P PF00459.20 AEO58768.1 - 6.8e-51 173.1 1.3 1.2e-50 172.3 0.9 1.3 1 1 0 1 1 1 1 Inositol monophosphatase family Ribosomal_L6 PF00347.18 AEO58769.1 - 0.0094 16.4 0.1 0.03 14.8 0.0 1.8 1 1 1 2 2 2 1 Ribosomal protein L6 Tht1 PF04163.7 AEO58770.1 - 2.1e-09 36.3 1.9 6.7e-09 34.6 1.3 1.8 1 1 0 1 1 1 1 Tht1-like nuclear fusion protein NPV_P10 PF05531.7 AEO58770.1 - 0.0099 16.1 7.2 0.27 11.5 0.1 3.1 2 1 0 2 2 2 1 Nucleopolyhedrovirus P10 protein AKNA PF12443.3 AEO58770.1 - 0.02 14.9 7.3 0.22 11.5 1.3 2.6 2 0 0 2 2 2 0 AT-hook-containing transcription factor Mis12 PF05859.7 AEO58770.1 - 0.024 14.4 4.6 0.094 12.5 0.1 2.8 2 1 1 3 3 3 0 Mis12 protein DUF948 PF06103.6 AEO58770.1 - 0.026 14.3 6.4 0.22 11.3 1.5 2.9 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF3610 PF12272.3 AEO58770.1 - 0.033 13.8 0.2 2.2 7.9 0.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3610) DUF3552 PF12072.3 AEO58770.1 - 0.034 13.3 10.6 0.39 9.8 0.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3552) Prominin PF05478.6 AEO58770.1 - 0.049 11.1 3.7 0.079 10.4 2.6 1.3 1 0 0 1 1 1 0 Prominin BLOC1_2 PF10046.4 AEO58770.1 - 0.05 13.7 10.2 1.6 8.9 3.4 2.6 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Lyase_8_N PF08124.6 AEO58770.1 - 0.068 12.0 2.3 0.083 11.7 0.5 1.7 2 0 0 2 2 2 0 Polysaccharide lyase family 8, N terminal alpha-helical domain DUF4200 PF13863.1 AEO58770.1 - 0.085 12.8 7.2 0.91 9.4 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Spc7 PF08317.6 AEO58770.1 - 0.094 11.3 15.2 0.11 11.1 4.9 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Prefoldin_2 PF01920.15 AEO58770.1 - 0.12 12.1 8.2 2.7 7.7 1.7 3.2 2 1 1 3 3 3 0 Prefoldin subunit Tropomyosin_1 PF12718.2 AEO58770.1 - 0.14 12.0 15.3 0.94 9.3 3.3 2.3 1 1 1 2 2 2 0 Tropomyosin like ADIP PF11559.3 AEO58770.1 - 0.28 11.0 17.7 1.2 9.0 1.4 2.5 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding GAS PF13851.1 AEO58770.1 - 0.32 10.1 13.3 0.12 11.5 2.6 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Mnd1 PF03962.10 AEO58770.1 - 0.48 10.0 11.9 0.63 9.6 0.5 2.2 1 1 0 2 2 2 0 Mnd1 family DUF3450 PF11932.3 AEO58770.1 - 0.49 9.6 14.5 0.61 9.2 6.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Atg14 PF10186.4 AEO58770.1 - 0.62 8.9 15.6 0.45 9.4 1.8 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 MCPsignal PF00015.16 AEO58770.1 - 1.3 8.4 12.4 12 5.3 7.6 2.3 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain PilO PF04350.8 AEO58770.1 - 1.4 8.8 6.5 1.7 8.5 1.1 2.4 2 0 0 2 2 2 0 Pilus assembly protein, PilO Sec8_exocyst PF04048.9 AEO58770.1 - 1.7 8.2 11.8 1.3 8.6 4.6 2.4 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain HAUS6_N PF14661.1 AEO58770.1 - 2.7 7.2 10.2 1.7 7.9 2.1 2.3 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus MbeD_MobD PF04899.7 AEO58770.1 - 3.1 7.7 9.8 2 8.4 0.8 2.9 2 0 0 2 2 2 0 MbeD/MobD like DUF4559 PF15112.1 AEO58770.1 - 3.3 6.8 10.7 0.4 9.7 2.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) Sec34 PF04136.10 AEO58770.1 - 3.5 7.2 9.0 1.9 8.1 2.7 2.6 2 1 0 2 2 2 0 Sec34-like family zf-C4H2 PF10146.4 AEO58770.1 - 3.8 7.4 8.1 14 5.6 1.7 2.4 1 1 1 2 2 2 0 Zinc finger-containing protein TBPIP PF07106.8 AEO58770.1 - 6 6.3 9.3 12 5.3 1.8 2.4 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CTP_transf_2 PF01467.21 AEO58772.1 - 1.4e-24 86.9 0.0 1.8e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase DUF3139 PF11337.3 AEO58773.1 - 0.013 15.7 0.9 0.014 15.6 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) DUF4234 PF14018.1 AEO58773.1 - 0.017 14.8 0.6 0.019 14.6 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) Oxidored_q2 PF00420.19 AEO58773.1 - 0.04 13.4 0.3 0.048 13.2 0.2 1.1 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L OppC_N PF12911.2 AEO58773.1 - 0.049 12.9 1.6 0.061 12.6 1.1 1.2 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C NfeD PF01957.13 AEO58773.1 - 0.071 13.2 0.0 0.077 13.1 0.0 1.0 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding DUF3592 PF12158.3 AEO58773.1 - 0.086 12.6 0.1 0.098 12.4 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3592) DUF4307 PF14155.1 AEO58773.1 - 0.098 12.4 0.2 0.12 12.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) DUF1183 PF06682.7 AEO58773.1 - 0.12 11.9 0.0 0.12 11.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Mem_trans PF03547.13 AEO58773.1 - 0.14 10.3 0.3 0.16 10.1 0.2 1.0 1 0 0 1 1 1 0 Membrane transport protein Chordopox_A13L PF05961.6 AEO58773.1 - 0.16 11.9 0.4 0.16 11.9 0.3 1.1 1 0 0 1 1 1 0 Chordopoxvirus A13L protein P12 PF12669.2 AEO58773.1 - 0.16 12.2 0.6 0.22 11.7 0.4 1.3 1 0 0 1 1 1 0 Virus attachment protein p12 family IncA PF04156.9 AEO58773.1 - 0.16 11.5 1.6 0.17 11.4 1.1 1.1 1 0 0 1 1 1 0 IncA protein Baculo_11_kDa PF06143.6 AEO58773.1 - 0.17 11.2 1.1 0.19 11.1 0.8 1.1 1 0 0 1 1 1 0 Baculovirus 11 kDa family Sigma_reg_N PF13800.1 AEO58773.1 - 0.22 11.5 1.2 0.23 11.5 0.9 1.1 1 0 0 1 1 1 0 Sigma factor regulator N-terminal PsbN PF02468.10 AEO58773.1 - 0.23 11.0 1.1 0.31 10.6 0.7 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) DUF1206 PF06724.6 AEO58773.1 - 1.1 9.0 5.7 0.43 10.3 2.3 1.6 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1206) TadE PF07811.7 AEO58773.1 - 1.3 8.9 4.8 1.9 8.4 3.3 1.5 1 1 0 1 1 1 0 TadE-like protein Chromo_shadow PF01393.14 AEO58774.1 - 2.5e-14 52.8 0.0 4e-13 48.9 0.0 2.2 2 0 0 2 2 2 1 Chromo shadow domain Chromo PF00385.19 AEO58774.1 - 4.5e-13 48.6 0.8 4.5e-13 48.6 0.6 3.1 4 1 0 4 4 4 1 Chromo (CHRromatin Organisation MOdifier) domain SPX PF03105.14 AEO58774.1 - 0.0031 17.3 0.9 0.0046 16.7 0.6 1.4 1 1 0 1 1 1 1 SPX domain zf-Di19 PF05605.7 AEO58775.1 - 0.017 15.2 0.1 0.043 13.9 0.1 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding HALZ PF02183.13 AEO58775.1 - 0.021 14.5 0.6 0.06 13.0 0.4 1.8 1 0 0 1 1 1 0 Homeobox associated leucine zipper zf-C2H2 PF00096.21 AEO58775.1 - 1.1 9.7 3.0 0.73 10.3 0.3 2.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type Nop14 PF04147.7 AEO58775.1 - 8.6 4.1 21.2 13 3.5 14.7 1.2 1 0 0 1 1 1 0 Nop14-like family tRNA-synt_2 PF00152.15 AEO58776.1 - 4e-84 282.2 1.1 5.3e-84 281.8 0.8 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 AEO58776.1 - 7.6e-12 44.9 0.1 1.6e-11 43.9 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 AEO58776.1 - 6.7e-09 35.2 0.1 0.00031 20.0 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) ABC_tran PF00005.22 AEO58777.1 - 5.7e-47 159.4 0.1 1.5e-25 90.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 AEO58777.1 - 1.9e-27 96.1 31.1 1e-17 64.2 10.5 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 AEO58777.1 - 4.8e-22 79.2 3.0 2e-08 34.5 0.4 4.2 3 1 0 3 3 3 3 AAA domain AAA_29 PF13555.1 AEO58777.1 - 1.1e-09 37.6 4.1 0.00086 18.7 0.4 3.6 3 0 0 3 3 3 2 P-loop containing region of AAA domain SMC_N PF02463.14 AEO58777.1 - 1.6e-07 30.8 3.7 0.066 12.4 0.0 4.0 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 AEO58777.1 - 0.0001 22.7 5.0 0.044 14.1 0.2 2.3 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 AEO58777.1 - 0.00029 20.0 0.2 0.5 9.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 AEO58777.1 - 0.00061 19.8 0.8 0.86 9.5 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.1 AEO58777.1 - 0.003 17.1 1.6 1.4 8.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 AEO58777.1 - 0.0042 16.5 0.2 3.4 7.0 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 AEO58777.1 - 0.018 14.8 0.1 25 4.7 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.1 AEO58777.1 - 0.025 13.6 0.0 5.5 5.9 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain SRP54 PF00448.17 AEO58777.1 - 0.03 13.7 1.4 5.9 6.2 0.3 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_22 PF13401.1 AEO58777.1 - 0.031 14.4 0.2 4.3 7.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain MutS_V PF00488.16 AEO58777.1 - 0.088 12.1 0.3 3.3 7.0 0.0 2.5 3 0 0 3 3 2 0 MutS domain V AAA_28 PF13521.1 AEO58777.1 - 0.11 12.4 1.2 29 4.5 0.5 3.0 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.13 AEO58777.1 - 0.12 11.8 0.2 1.4 8.3 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_10 PF12846.2 AEO58777.1 - 0.12 11.8 1.1 7.3 5.9 0.3 2.4 2 0 0 2 2 2 0 AAA-like domain G-alpha PF00503.15 AEO58777.1 - 0.2 10.3 0.0 2.2 6.8 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit AAA_19 PF13245.1 AEO58777.1 - 0.41 10.4 5.5 8.1 6.2 0.0 3.1 3 0 0 3 3 3 0 Part of AAA domain DUF87 PF01935.12 AEO58777.1 - 0.82 9.4 3.8 10 5.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_13 PF13166.1 AEO58777.1 - 1.4 7.3 0.8 12 4.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF3753 PF12575.3 AEO58778.1 - 0.053 13.3 0.9 0.15 11.8 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) DctQ PF04290.7 AEO58778.1 - 0.4 10.4 8.8 4.1 7.1 0.1 2.3 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component His_Phos_1 PF00300.17 AEO58779.1 - 1e-13 51.6 0.0 4.3e-13 49.6 0.0 1.8 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) LigB PF02900.13 AEO58779.1 - 0.054 12.4 0.2 0.085 11.8 0.1 1.2 1 0 0 1 1 1 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase VHS PF00790.14 AEO58780.1 - 3.2e-42 143.5 1.2 5.5e-41 139.5 0.0 2.3 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 AEO58780.1 - 8.3e-16 57.6 3.2 1.5e-15 56.8 2.2 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 AEO58780.1 - 0.00023 20.4 14.3 0.02 14.4 0.3 3.4 3 0 0 3 3 3 2 Ubiquitin interaction motif zf-DHHC PF01529.15 AEO58780.1 - 0.0041 16.5 1.7 0.0041 16.5 1.2 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase FYVE_2 PF02318.11 AEO58780.1 - 0.031 14.1 1.4 0.082 12.8 1.0 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger Ribosomal_S30AE PF02482.14 AEO58780.1 - 0.1 13.0 1.9 0.32 11.4 1.3 1.9 1 0 0 1 1 1 0 Sigma 54 modulation protein / S30EA ribosomal protein DUF4254 PF14063.1 AEO58780.1 - 0.52 9.9 3.2 16 5.1 0.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF4254) UCH PF00443.24 AEO58781.1 - 4.4e-41 140.7 0.0 6.2e-41 140.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AEO58781.1 - 5.5e-11 42.4 0.0 9.6e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 AEO58781.1 - 0.00043 20.6 0.0 0.00099 19.4 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain AMP-binding PF00501.23 AEO58782.1 - 1.1e-80 271.1 0.1 1.5e-80 270.6 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Fungal_trans_2 PF11951.3 AEO58783.1 - 0.019 13.5 0.2 0.025 13.2 0.2 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Dynamin_N PF00350.18 AEO58784.1 - 1.8e-06 27.8 0.0 2.3e-06 27.5 0.0 1.3 1 1 0 1 1 1 1 Dynamin family FtsK_SpoIIIE PF01580.13 AEO58784.1 - 0.00077 18.9 0.2 0.51 9.7 0.0 2.1 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_23 PF13476.1 AEO58784.1 - 0.0018 18.6 0.5 0.077 13.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 AEO58784.1 - 0.0023 18.4 0.0 0.0055 17.1 0.0 1.6 1 1 0 1 1 1 1 Miro-like protein ABC_tran PF00005.22 AEO58784.1 - 0.0023 18.2 0.4 0.0034 17.6 0.3 1.5 1 1 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.18 AEO58784.1 - 0.0081 16.1 0.0 0.012 15.5 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Zeta_toxin PF06414.7 AEO58784.1 - 0.012 14.7 0.6 0.027 13.5 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin PRK PF00485.13 AEO58784.1 - 0.016 14.7 0.1 0.033 13.7 0.0 1.5 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.1 AEO58784.1 - 0.016 15.1 0.3 0.022 14.7 0.2 1.5 1 1 0 1 1 1 0 AAA ATPase domain T2SE PF00437.15 AEO58784.1 - 0.021 13.7 0.1 0.045 12.6 0.1 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein cobW PF02492.14 AEO58784.1 - 0.033 13.6 0.1 0.054 12.9 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 AEO58784.1 - 0.053 13.0 0.1 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 AEO58784.1 - 0.062 12.4 0.0 0.093 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 AEO58784.1 - 0.065 14.0 0.9 0.12 13.1 0.6 1.7 1 1 0 1 1 1 0 AAA domain UPF0079 PF02367.12 AEO58784.1 - 0.09 12.4 0.6 0.22 11.1 0.3 1.6 1 1 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 KAP_NTPase PF07693.9 AEO58784.1 - 0.12 11.2 0.5 0.32 9.9 0.0 1.6 1 1 0 2 2 2 0 KAP family P-loop domain ArgK PF03308.11 AEO58784.1 - 0.14 10.8 0.2 0.23 10.2 0.1 1.2 1 0 0 1 1 1 0 ArgK protein AAA_25 PF13481.1 AEO58784.1 - 0.15 11.4 0.1 0.33 10.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 AEO58784.1 - 1.1 9.0 3.2 0.98 9.1 0.4 1.9 1 1 1 2 2 2 0 Domain of unknown function DUF87 DUF3295 PF11702.3 AEO58787.1 - 3.7e-155 517.7 29.5 4.5e-155 517.4 20.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.5 AEO58787.1 - 6.3e-13 48.0 2.2 1.2e-12 47.1 1.5 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) zf-CHY PF05495.7 AEO58788.1 - 1.5e-16 60.3 27.4 9.2e-16 57.7 10.1 3.3 3 0 0 3 3 3 2 CHY zinc finger Mu-like_Com PF10122.4 AEO58788.1 - 4.7e-05 22.3 0.5 0.00019 20.4 0.4 2.1 1 0 0 1 1 1 1 Mu-like prophage protein Com RWD PF05773.17 AEO58788.1 - 0.00015 21.5 0.3 0.0043 16.9 0.0 2.5 2 0 0 2 2 2 1 RWD domain VHS PF00790.14 AEO58789.1 - 1.8e-26 92.4 0.0 4.3e-26 91.2 0.0 1.6 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 AEO58789.1 - 4.1e-09 36.3 2.1 5.7e-09 35.8 0.8 1.8 2 0 0 2 2 2 1 GAT domain Pox_Ag35 PF03286.9 AEO58789.1 - 0.61 9.5 13.3 0.26 10.7 5.0 2.4 2 0 0 2 2 2 0 Pox virus Ag35 surface protein zf-C2H2_2 PF12756.2 AEO58790.1 - 1.1e-36 124.9 8.4 1.5e-30 105.2 0.7 3.4 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 AEO58790.1 - 5.2e-08 32.7 13.5 7.3e-06 25.9 2.5 3.9 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 AEO58790.1 - 5.1e-07 29.6 8.5 1.2e-06 28.5 2.0 2.9 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 AEO58790.1 - 0.0043 17.3 18.7 0.17 12.2 0.3 4.7 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-DBF PF07535.7 AEO58790.1 - 0.017 14.7 0.3 0.017 14.7 0.2 3.4 4 0 0 4 4 4 0 DBF zinc finger Rotamase_2 PF13145.1 AEO58790.1 - 0.099 13.2 1.6 1.2 9.8 0.1 2.5 2 0 0 2 2 2 0 PPIC-type PPIASE domain zf-C2H2_6 PF13912.1 AEO58790.1 - 0.24 11.3 7.5 4.2 7.4 0.0 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger HECT PF00632.20 AEO58791.1 - 1.4e-68 231.3 0.0 2.2e-68 230.7 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Cpn60_TCP1 PF00118.19 AEO58792.1 - 4.3e-148 493.9 1.7 4.9e-148 493.7 1.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family NotI PF12183.3 AEO58792.1 - 0.042 12.9 0.9 0.86 8.6 0.1 2.3 2 0 0 2 2 2 0 Restriction endonuclease NotI GTP_EFTU PF00009.22 AEO58793.1 - 2.8e-46 157.3 0.0 4.4e-46 156.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 AEO58793.1 - 2.3e-23 82.1 1.7 4.4e-23 81.1 1.1 1.5 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D3 PF03143.12 AEO58793.1 - 1.5e-08 34.6 0.0 6.9e-08 32.5 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.18 AEO58793.1 - 1.1e-05 25.3 0.0 2.6e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 AEO58793.1 - 1.3e-05 25.2 0.0 4.4e-05 23.5 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Miro PF08477.8 AEO58793.1 - 0.0022 18.4 0.0 0.0058 17.1 0.0 1.8 1 1 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 AEO58793.1 - 0.019 14.1 0.0 1.4 8.0 0.0 2.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit HSP70 PF00012.15 AEO58794.1 - 4.2e-271 900.1 13.9 4.7e-271 900.0 9.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 AEO58794.1 - 7.7e-21 74.0 1.7 2.3e-19 69.1 0.3 2.2 2 0 0 2 2 2 2 MreB/Mbl protein DDR PF08841.5 AEO58794.1 - 0.0042 15.9 0.3 0.072 11.9 0.1 2.3 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 AEO58794.1 - 0.0086 15.2 5.3 0.012 14.7 0.1 3.0 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase FtsA PF14450.1 AEO58794.1 - 0.015 15.0 8.7 4.5 7.1 0.5 3.9 3 1 0 3 3 3 0 Cell division protein FtsA FGGY_C PF02782.11 AEO58794.1 - 0.055 13.0 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain SpoIIAA-like PF11964.3 AEO58794.1 - 0.7 10.2 3.7 7.9 6.8 0.1 3.1 3 0 0 3 3 3 0 SpoIIAA-like Herpes_UL95 PF03038.9 AEO58797.1 - 0.0055 15.6 0.1 0.0072 15.2 0.1 1.1 1 0 0 1 1 1 1 UL95 family DUF500 PF04366.7 AEO58798.1 - 8.9e-44 147.9 0.1 1.7e-43 147.0 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 AEO58798.1 - 3.5e-15 55.1 0.2 1.6e-14 53.0 0.0 2.0 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 AEO58798.1 - 7.8e-14 50.9 0.0 1.3e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 AEO58798.1 - 5.4e-12 45.0 0.0 1.1e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Synaptobrevin PF00957.16 AEO58799.1 - 0.06 12.9 0.5 0.51 9.9 0.2 2.0 1 1 1 2 2 2 0 Synaptobrevin ArfGap PF01412.13 AEO58800.1 - 1.2e-40 137.9 0.3 1.9e-40 137.3 0.2 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf SelR PF01641.13 AEO58801.1 - 4.3e-50 168.5 0.0 5.3e-50 168.2 0.0 1.1 1 0 0 1 1 1 1 SelR domain DZR PF12773.2 AEO58801.1 - 0.004 16.9 2.5 0.17 11.7 0.1 2.4 2 1 0 2 2 2 2 Double zinc ribbon DUF2296 PF10058.4 AEO58801.1 - 0.018 14.8 0.5 0.93 9.2 0.0 2.3 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) Zn_ribbon_recom PF13408.1 AEO58801.1 - 1.2 9.4 3.9 15 5.9 0.1 2.3 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain ARID PF01388.16 AEO58803.1 - 1.2e-20 73.1 0.0 2.8e-20 71.9 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain HEAT_2 PF13646.1 AEO58803.1 - 0.004 17.4 0.2 0.22 11.8 0.1 2.8 2 0 0 2 2 2 1 HEAT repeats Arm PF00514.18 AEO58803.1 - 0.083 12.7 0.9 7.9 6.4 0.1 3.0 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat DUF605 PF04652.11 AEO58803.1 - 8.8 5.6 19.6 18 4.5 13.6 1.4 1 0 0 1 1 1 0 Vta1 like adh_short PF00106.20 AEO58804.1 - 5.9e-30 104.3 1.3 1e-29 103.6 0.9 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO58804.1 - 1.5e-27 96.9 0.2 2.2e-27 96.3 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO58804.1 - 9.9e-11 41.6 0.4 1.7e-10 40.8 0.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 AEO58804.1 - 5.5e-06 25.9 0.2 2.4e-05 23.8 0.2 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PA PF02225.17 AEO58804.1 - 0.0033 17.0 0.1 0.0096 15.6 0.1 1.8 1 0 0 1 1 1 1 PA domain Polysacc_synt_2 PF02719.10 AEO58804.1 - 0.009 14.9 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 AEO58804.1 - 0.012 14.3 0.0 0.017 13.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Pkinase PF00069.20 AEO58805.1 - 4e-72 242.4 0.0 5.7e-72 241.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO58805.1 - 2.5e-46 157.8 0.0 4e-46 157.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 AEO58805.1 - 3.2e-17 62.6 0.1 9.1e-17 61.2 0.0 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 AEO58805.1 - 3.9e-08 32.6 0.0 6.5e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AEO58805.1 - 0.026 14.2 2.7 0.072 12.8 0.0 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 AEO58805.1 - 0.041 12.9 0.1 0.24 10.4 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DSHCT PF08148.7 AEO58805.1 - 0.099 11.8 0.2 0.33 10.1 0.0 1.9 2 0 0 2 2 2 0 DSHCT (NUC185) domain KH_1 PF00013.24 AEO58806.1 - 5.8e-97 317.3 35.0 7.4e-14 51.1 0.1 12.9 13 1 0 13 13 13 9 KH domain KH_3 PF13014.1 AEO58806.1 - 2.1e-70 231.4 29.4 4.9e-11 42.0 0.1 12.3 12 0 0 12 12 12 9 KH domain SLS PF14611.1 AEO58806.1 - 1.4e-16 60.5 0.1 0.0007 19.0 0.0 7.6 5 2 2 8 8 8 3 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.12 AEO58806.1 - 8.2e-15 54.1 18.8 0.024 14.1 0.1 8.9 9 0 0 9 9 9 5 KH domain KH_4 PF13083.1 AEO58806.1 - 0.1 12.2 6.6 1.2 8.8 0.0 5.4 6 1 1 7 7 7 0 KH domain Atx10homo_assoc PF09759.4 AEO58807.1 - 8.8e-11 41.4 0.0 2.6e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain PNP_UDP_1 PF01048.15 AEO58808.1 - 6.5e-39 133.2 1.1 7.8e-39 133.0 0.8 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Med13_C PF06333.7 AEO58809.1 - 5.1e-119 397.5 0.0 8.2e-119 396.8 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit 13 C-terminal Med13_N PF11597.3 AEO58809.1 - 8.9e-59 199.1 0.1 4.1e-58 196.9 0.0 2.0 2 0 0 2 2 2 1 Mediator complex subunit 13 N-terminal NUC153 PF08159.7 AEO58810.1 - 7.9e-14 50.9 1.4 1.7e-13 49.8 0.9 1.6 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 AEO58810.1 - 4.9e-05 23.0 0.0 0.014 15.2 0.0 3.4 3 0 0 3 3 3 1 WD domain, G-beta repeat Dynactin_p62 PF05502.8 AEO58810.1 - 0.88 8.2 5.1 0.92 8.1 0.2 2.1 1 1 1 2 2 2 0 Dynactin p62 family PHO4 PF01384.15 AEO58811.1 - 0.032 12.9 0.0 0.032 12.9 0.0 1.0 1 0 0 1 1 1 0 Phosphate transporter family Sigma_reg_N PF13800.1 AEO58811.1 - 0.076 13.0 0.1 0.1 12.6 0.1 1.1 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF3302 PF11742.3 AEO58811.1 - 0.11 12.3 0.8 0.14 11.9 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3302) Sex_peptide PF08138.6 AEO58811.1 - 0.14 12.0 0.1 0.26 11.1 0.1 1.5 1 0 0 1 1 1 0 Sex peptide (SP) family CD99L2 PF12301.3 AEO58811.1 - 0.25 11.0 1.2 0.48 10.0 0.2 1.8 1 1 1 2 2 2 0 CD99 antigen like protein 2 CENP-F_leu_zip PF10473.4 AEO58812.1 - 0.0025 17.6 92.6 0.022 14.6 8.6 5.9 2 1 2 5 5 5 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPV_P10 PF05531.7 AEO58812.1 - 0.11 12.7 32.8 0.88 9.8 0.5 7.8 4 2 3 7 7 7 0 Nucleopolyhedrovirus P10 protein AAA_13 PF13166.1 AEO58812.1 - 0.22 9.9 79.6 0.012 14.1 21.9 3.3 1 1 2 3 3 3 0 AAA domain Filament PF00038.16 AEO58812.1 - 0.25 10.7 89.5 0.0072 15.8 27.4 2.3 2 0 0 2 2 2 0 Intermediate filament protein Ribosomal_L33 PF00471.15 AEO58813.1 - 1.9e-06 27.9 0.0 2.6e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 Aminotran_1_2 PF00155.16 AEO58814.1 - 5.3e-39 134.1 0.0 7.4e-39 133.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II UPF0154 PF03672.8 AEO58814.1 - 0.078 12.6 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) RPN7 PF10602.4 AEO58815.1 - 2.7e-58 196.2 1.2 2.7e-58 196.2 0.8 1.6 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.22 AEO58815.1 - 4.1e-13 49.5 0.0 8.5e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 PCI domain TPR_7 PF13176.1 AEO58815.1 - 0.13 12.1 0.9 0.61 10.0 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 AEO58815.1 - 0.22 12.2 2.4 1.7 9.4 0.1 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 AEO58815.1 - 5.4 7.7 6.8 2.8 8.5 0.1 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat Pox_MCEL PF03291.11 AEO58816.1 - 4.7e-66 222.9 0.0 1.1e-45 156.0 0.0 2.4 2 1 0 2 2 2 2 mRNA capping enzyme Methyltransf_12 PF08242.7 AEO58816.1 - 2e-08 34.5 0.1 0.0062 16.9 0.0 2.8 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_18 PF12847.2 AEO58816.1 - 5e-08 33.5 0.0 1.5e-07 31.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO58816.1 - 5.3e-07 29.9 0.0 1.8e-06 28.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO58816.1 - 9e-07 29.3 0.2 4.8e-05 23.7 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO58816.1 - 3.9e-06 26.5 0.0 2.6e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO58816.1 - 2.3e-05 24.1 0.0 4.8e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 AEO58816.1 - 0.00049 19.1 0.0 0.00098 18.1 0.0 1.4 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Raftlin PF15250.1 AEO58816.1 - 0.0012 17.4 0.1 0.0012 17.4 0.1 1.5 2 0 0 2 2 2 1 Raftlin Methyltransf_9 PF08003.6 AEO58816.1 - 0.015 14.0 0.0 0.027 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) EF_assoc_2 PF08356.7 AEO58817.1 - 3.9e-35 119.4 0.0 8.4e-35 118.4 0.0 1.6 1 0 0 1 1 1 1 EF hand associated Miro PF08477.8 AEO58817.1 - 7.5e-35 120.0 0.0 5.9e-19 68.7 0.0 2.3 2 0 0 2 2 2 2 Miro-like protein EF_assoc_1 PF08355.7 AEO58817.1 - 6.2e-33 111.9 0.1 1.4e-32 110.7 0.1 1.6 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 AEO58817.1 - 3.8e-24 84.9 0.0 8.3e-16 57.7 0.0 2.2 2 0 0 2 2 2 2 Ras family MMR_HSR1 PF01926.18 AEO58817.1 - 2e-08 34.1 0.0 6.3e-05 22.9 0.0 2.7 2 1 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_7 PF13499.1 AEO58817.1 - 4.5e-08 33.1 0.2 0.00027 21.0 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 AEO58817.1 - 3.8e-07 28.9 2.6 0.0052 15.9 0.1 2.7 2 0 0 2 2 2 2 EF hand AAA_16 PF13191.1 AEO58817.1 - 1.1e-06 28.7 0.0 0.032 14.2 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 AEO58817.1 - 2.2e-06 27.1 0.0 0.0048 16.4 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 AEO58817.1 - 3e-06 27.3 0.0 0.04 14.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.18 AEO58817.1 - 1.9e-05 24.5 0.1 0.31 10.8 0.1 3.2 2 1 1 3 3 3 2 Dynamin family EF-hand_6 PF13405.1 AEO58817.1 - 6.5e-05 22.4 2.6 0.088 12.7 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain AAA_24 PF13479.1 AEO58817.1 - 0.0002 21.0 0.0 0.024 14.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 AEO58817.1 - 0.00021 21.6 0.0 0.55 10.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter GTP_EFTU PF00009.22 AEO58817.1 - 0.00035 20.0 0.0 1.6 8.1 0.0 3.1 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain EF-hand_5 PF13202.1 AEO58817.1 - 0.0004 19.5 4.3 0.41 10.0 1.0 2.8 2 0 0 2 2 2 2 EF hand DUF258 PF03193.11 AEO58817.1 - 0.0011 18.2 0.0 0.88 8.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 AEO58817.1 - 0.0012 18.2 0.0 1.5 8.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 AEO58817.1 - 0.0012 18.4 0.0 1.6 8.3 0.0 2.6 2 0 0 2 2 2 2 NACHT domain RNA_helicase PF00910.17 AEO58817.1 - 0.0013 18.8 0.0 0.33 11.1 0.0 2.5 2 0 0 2 2 2 1 RNA helicase MobB PF03205.9 AEO58817.1 - 0.0019 17.8 0.1 0.22 11.2 0.1 2.3 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF815 PF05673.8 AEO58817.1 - 0.0019 17.1 0.0 0.5 9.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 AEO58817.1 - 0.0044 16.7 0.0 0.35 10.5 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase AAA_23 PF13476.1 AEO58817.1 - 0.01 16.2 0.0 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 AEO58817.1 - 0.011 15.6 0.0 5.1 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain EF-hand_10 PF14788.1 AEO58817.1 - 0.011 15.3 1.0 0.066 12.8 0.1 2.3 2 0 0 2 2 2 0 EF hand SMC_N PF02463.14 AEO58817.1 - 0.011 14.9 0.0 0.53 9.4 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_33 PF13671.1 AEO58817.1 - 0.012 15.5 0.0 4 7.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 AEO58817.1 - 0.022 14.3 0.0 1.1 8.7 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase cobW PF02492.14 AEO58817.1 - 0.047 13.1 0.2 5.6 6.3 0.1 3.6 3 1 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 AEO58817.1 - 0.049 13.0 0.0 5.2 6.4 0.0 2.6 3 0 0 3 3 3 0 AAA-like domain SPARC_Ca_bdg PF10591.4 AEO58817.1 - 0.051 13.6 0.1 4.6 7.3 0.0 3.3 3 1 1 4 4 3 0 Secreted protein acidic and rich in cysteine Ca binding region IIGP PF05049.8 AEO58817.1 - 0.073 11.8 0.1 1.6 7.4 0.0 2.3 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Septin PF00735.13 AEO58817.1 - 0.082 11.9 0.0 0.53 9.2 0.0 2.0 2 0 0 2 2 2 0 Septin DUF87 PF01935.12 AEO58817.1 - 0.088 12.6 0.0 7.2 6.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 ATP_bind_1 PF03029.12 AEO58817.1 - 0.096 12.2 0.1 16 4.9 0.0 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.13 AEO58817.1 - 0.11 11.9 0.0 17 4.8 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_18 PF13238.1 AEO58817.1 - 0.16 12.2 0.0 12 6.2 0.0 2.7 2 1 0 2 2 2 0 AAA domain EF-hand_8 PF13833.1 AEO58817.1 - 0.26 10.9 2.4 5.6 6.6 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain pair AIG1 PF04548.11 AEO58817.1 - 0.45 9.5 1.3 1.4 8.0 0.2 2.3 3 0 0 3 3 3 0 AIG1 family WD40 PF00400.27 AEO58818.1 - 2.5e-23 81.0 8.2 1.9e-06 27.5 1.1 4.5 4 0 0 4 4 4 4 WD domain, G-beta repeat eIF2A PF08662.6 AEO58818.1 - 0.00067 19.4 0.0 0.0044 16.7 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 AEO58818.1 - 0.00067 17.6 0.0 0.0013 16.6 0.0 1.3 1 1 0 1 1 1 1 IKI3 family PD40 PF07676.7 AEO58818.1 - 0.06 13.0 0.1 20 4.9 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Arrestin_C PF02752.17 AEO58819.1 - 9.6e-18 64.6 0.0 1.8e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 AEO58819.1 - 3.5e-13 49.6 0.0 7.8e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 AEO58819.1 - 0.00043 19.8 0.0 0.0011 18.5 0.0 1.7 1 0 0 1 1 1 1 Arrestin_N terminal like PH PF00169.24 AEO58820.1 - 0.0026 17.9 0.0 0.0053 16.9 0.0 1.5 1 0 0 1 1 1 1 PH domain Apolipoprotein PF01442.13 AEO58820.1 - 0.0067 15.9 2.4 0.013 15.0 1.6 1.4 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain eRF1_3 PF03465.10 AEO58820.1 - 0.038 14.2 0.2 0.23 11.7 0.0 2.1 1 1 1 2 2 2 0 eRF1 domain 3 Clr5 PF14420.1 AEO58821.1 - 1.2e-12 47.5 0.1 1.3e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 Clr5 domain Fer2_2 PF01799.15 AEO58821.1 - 0.15 11.9 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 [2Fe-2S] binding domain Clr5 PF14420.1 AEO58822.1 - 0.019 14.8 0.1 0.029 14.2 0.1 1.3 1 0 0 1 1 1 0 Clr5 domain zf-Nse PF11789.3 AEO58823.1 - 4.7e-21 74.0 0.6 7.7e-21 73.3 0.4 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.15 AEO58823.1 - 3.7e-05 23.1 0.4 6.3e-05 22.4 0.2 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-RING_2 PF13639.1 AEO58823.1 - 0.00064 19.5 0.3 0.0011 18.7 0.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 AEO58823.1 - 0.00081 19.0 0.6 0.0023 17.6 0.4 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 AEO58823.1 - 0.0064 16.2 0.1 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 AEO58823.1 - 0.0087 15.8 0.0 0.021 14.6 0.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger U-box PF04564.10 AEO58823.1 - 0.026 14.4 0.0 0.063 13.2 0.0 1.6 1 0 0 1 1 1 0 U-box domain zf-rbx1 PF12678.2 AEO58823.1 - 0.033 14.2 0.0 0.067 13.2 0.0 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger Rad50_zn_hook PF04423.9 AEO58823.1 - 0.07 12.6 0.4 0.29 10.6 0.0 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-C3HC4 PF00097.20 AEO58823.1 - 0.086 12.5 0.9 0.15 11.7 0.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 AEO58823.1 - 0.09 12.6 0.7 0.15 11.9 0.5 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 AEO58823.1 - 0.13 12.2 1.0 0.23 11.5 0.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Glyco_hydro_7 PF00840.15 AEO58824.1 - 2e-42 145.1 7.4 2.2e-42 144.9 5.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Colipase-like PF15083.1 AEO58824.1 - 0.077 12.9 0.5 0.27 11.1 0.0 1.9 2 0 0 2 2 2 0 Colipase-like Fapy_DNA_glyco PF01149.19 AEO58825.1 - 2.2e-23 82.8 0.0 3.9e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.9 AEO58825.1 - 9.3e-21 73.3 0.0 2e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.6 AEO58825.1 - 0.0014 17.2 0.0 0.0078 14.8 0.0 2.0 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) DUF4078 PF13300.1 AEO58828.1 - 3e-29 100.9 18.7 3e-29 100.9 13.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4078) APG6 PF04111.7 AEO58828.1 - 1.9 7.4 7.7 4 6.3 5.4 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 Homoserine_dh PF00742.14 AEO58829.1 - 1.5e-52 177.8 0.0 2.1e-52 177.3 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 AEO58829.1 - 2.2e-19 69.9 0.0 3.9e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Methyltransf_4 PF02390.12 AEO58830.1 - 6.1e-53 178.8 0.0 7.8e-53 178.4 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 AEO58830.1 - 3.5e-05 23.8 0.0 7.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO58830.1 - 0.00016 22.2 0.0 0.00028 21.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 AEO58830.1 - 0.013 14.4 0.0 0.024 13.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) MTS PF05175.9 AEO58830.1 - 0.014 14.8 0.0 0.045 13.1 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.1 AEO58830.1 - 0.018 14.6 0.0 0.031 13.8 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 AEO58830.1 - 0.026 15.0 0.0 0.061 13.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 AEO58830.1 - 0.071 13.5 0.0 0.58 10.6 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain Ndc80_HEC PF03801.8 AEO58831.1 - 3.9e-63 211.6 0.1 6.8e-63 210.8 0.1 1.4 1 0 0 1 1 1 1 HEC/Ndc80p family WASH_WAHD PF11945.3 AEO58831.1 - 0.0018 17.6 4.1 0.0018 17.6 2.9 2.2 2 0 0 2 2 2 1 WAHD domain of WASH complex DUF1664 PF07889.7 AEO58831.1 - 0.0075 16.0 0.9 0.0075 16.0 0.6 4.4 2 2 2 4 4 4 1 Protein of unknown function (DUF1664) OmpH PF03938.9 AEO58831.1 - 0.087 12.7 37.1 0.63 9.9 7.2 3.4 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Tropomyosin_1 PF12718.2 AEO58831.1 - 0.2 11.4 61.0 0.26 11.1 11.5 4.6 2 2 2 4 4 4 0 Tropomyosin like Filament PF00038.16 AEO58831.1 - 1.1 8.7 49.9 1.3 8.3 14.7 3.1 2 1 0 2 2 2 0 Intermediate filament protein V_ATPase_I PF01496.14 AEO58831.1 - 1.6 6.4 30.2 0.72 7.6 5.5 2.3 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF3584 PF12128.3 AEO58831.1 - 5.2 4.2 42.9 1.7 5.8 12.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Spc7 PF08317.6 AEO58831.1 - 7.5 5.1 39.5 1.5 7.3 9.3 2.8 2 1 0 2 2 2 0 Spc7 kinetochore protein Pex14_N PF04695.8 AEO58832.1 - 2.4e-40 137.7 0.0 2.4e-40 137.7 0.0 2.7 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region IncA PF04156.9 AEO58832.1 - 2.2e-05 24.1 0.0 2.8e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 IncA protein zf-C4H2 PF10146.4 AEO58832.1 - 6.3e-05 23.0 2.1 6.3e-05 23.0 1.5 1.9 2 0 0 2 2 2 1 Zinc finger-containing protein ERM PF00769.14 AEO58832.1 - 0.00017 21.2 6.7 0.00035 20.1 4.7 1.5 1 0 0 1 1 1 1 Ezrin/radixin/moesin family DUF3584 PF12128.3 AEO58832.1 - 0.0079 13.5 11.1 0.01 13.2 7.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) HLH PF00010.21 AEO58832.1 - 0.022 14.4 8.0 0.41 10.3 0.2 3.3 1 1 2 3 3 3 0 Helix-loop-helix DNA-binding domain CENP-Q PF13094.1 AEO58832.1 - 0.044 13.8 8.0 0.083 12.9 5.6 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF848 PF05852.6 AEO58832.1 - 0.059 13.2 9.6 0.1 12.4 6.7 1.3 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Transposase_22 PF02994.9 AEO58832.1 - 0.085 11.3 5.0 0.11 11.0 3.0 1.4 1 1 0 1 1 1 0 L1 transposable element PilJ PF13675.1 AEO58832.1 - 0.13 12.5 4.1 0.91 9.8 2.8 2.2 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term CR6_interact PF10147.4 AEO58832.1 - 0.27 10.5 6.3 0.16 11.2 2.6 1.8 1 1 1 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF342 PF03961.8 AEO58832.1 - 0.3 9.4 2.9 0.5 8.7 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) tRNA-synt_His PF13393.1 AEO58832.1 - 0.53 9.2 3.0 7 5.6 0.0 2.1 1 1 1 2 2 2 0 Histidyl-tRNA synthetase DUF724 PF05266.9 AEO58832.1 - 0.6 9.6 6.3 1 8.9 4.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ADIP PF11559.3 AEO58832.1 - 0.61 9.9 13.0 1.7 8.5 8.9 1.7 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.7 AEO58832.1 - 0.67 9.6 11.9 0.22 11.2 4.6 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Baculo_PEP_C PF04513.7 AEO58832.1 - 0.71 9.6 9.6 1.9 8.3 2.2 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.6 AEO58832.1 - 0.73 8.4 9.3 1.1 7.8 6.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Syntaxin PF00804.20 AEO58832.1 - 1.4 9.0 11.0 14 5.8 7.6 2.2 1 1 0 1 1 1 0 Syntaxin Atg14 PF10186.4 AEO58832.1 - 1.6 7.6 10.4 2.4 7.0 7.2 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Syntaxin-6_N PF09177.6 AEO58832.1 - 1.6 9.1 6.3 2.1 8.8 2.8 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF4164 PF13747.1 AEO58832.1 - 1.9 8.6 14.0 1.5 9.0 6.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) DUF1043 PF06295.7 AEO58832.1 - 2.1 7.9 4.7 2.4 7.8 2.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) TBPIP PF07106.8 AEO58832.1 - 2.3 7.7 10.6 0.81 9.2 2.4 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1664 PF07889.7 AEO58832.1 - 3.1 7.6 4.9 4.8 7.0 2.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) AAA_13 PF13166.1 AEO58832.1 - 4.3 5.6 12.2 8.5 4.7 8.5 1.3 1 1 0 1 1 1 0 AAA domain Bacillus_HBL PF05791.6 AEO58832.1 - 5.2 6.4 9.3 1.4 8.2 2.8 2.0 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) SlyX PF04102.7 AEO58832.1 - 6.9 7.1 8.3 0.89 9.9 1.6 2.6 2 1 1 3 3 2 0 SlyX Bap31 PF05529.7 AEO58832.1 - 9.9 5.5 6.8 19 4.6 4.7 1.5 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like Abhydrolase_3 PF07859.8 AEO58833.1 - 5.3e-42 143.7 1.0 2.8e-41 141.4 0.7 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AEO58833.1 - 0.0002 21.1 0.1 0.00036 20.3 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 AEO58833.1 - 0.00062 18.5 0.3 0.0044 15.7 0.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) FAD_binding_4 PF01565.18 AEO58834.1 - 1.9e-17 63.0 0.0 3.1e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HeLo PF14479.1 AEO58835.1 - 8.6e-54 182.4 0.1 1.4e-53 181.8 0.1 1.3 1 0 0 1 1 1 1 Prion-inhibition and propagation Patatin PF01734.17 AEO58836.1 - 1.1e-34 120.2 0.0 1.9e-34 119.3 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase Na_Ca_ex PF01699.19 AEO58837.1 - 6.1e-49 165.2 32.1 6.8e-26 90.5 5.8 2.4 3 0 0 3 3 3 2 Sodium/calcium exchanger protein MscS_TM PF12794.2 AEO58837.1 - 0.0022 16.6 1.1 0.0022 16.6 0.8 2.8 2 1 1 3 3 3 1 Mechanosensitive ion channel inner membrane domain 1 DUF4271 PF14093.1 AEO58837.1 - 3.2 7.3 13.8 0.2 11.3 0.4 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4271) zf-C2H2 PF00096.21 AEO58838.1 - 2e-22 78.1 24.6 6.1e-06 26.2 0.1 4.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 AEO58838.1 - 6.9e-20 70.2 26.4 3.1e-07 30.3 0.7 4.7 5 0 0 5 5 4 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 AEO58838.1 - 3.1e-15 55.3 24.2 0.00028 20.9 2.6 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 AEO58838.1 - 1.3e-05 25.1 3.6 1.8 8.7 0.0 4.6 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 AEO58838.1 - 0.0011 18.8 13.5 0.46 10.4 0.3 4.2 4 0 0 4 4 4 2 C2H2-type zinc finger ADK_lid PF05191.9 AEO58838.1 - 0.02 14.5 3.7 2.4 7.8 0.1 3.6 3 0 0 3 3 3 0 Adenylate kinase, active site lid zf-met PF12874.2 AEO58838.1 - 0.038 14.2 12.7 4.9 7.4 0.4 4.5 5 0 0 5 5 5 0 Zinc-finger of C2H2 type XPA_N PF01286.13 AEO58838.1 - 0.19 11.4 0.2 0.19 11.4 0.1 3.2 4 0 0 4 4 4 0 XPA protein N-terminal Zn-ribbon_8 PF09723.5 AEO58838.1 - 0.2 11.6 10.4 15 5.6 0.2 3.8 2 1 2 4 4 4 0 Zinc ribbon domain C1_1 PF00130.17 AEO58838.1 - 0.27 10.9 4.0 0.56 9.9 0.7 2.3 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-TRAF PF02176.13 AEO58838.1 - 0.32 11.3 8.3 1.7 9.0 0.4 2.5 1 1 1 2 2 2 0 TRAF-type zinc finger DUF2072 PF09845.4 AEO58838.1 - 0.49 10.3 1.9 1.2 9.0 1.3 1.7 1 1 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) zf-Mss51 PF13824.1 AEO58838.1 - 0.8 9.6 4.3 3.8 7.4 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 LIM PF00412.17 AEO58838.1 - 1.6 8.8 5.2 22 5.2 0.1 3.0 2 1 1 3 3 3 0 LIM domain DUF2256 PF10013.4 AEO58838.1 - 2.4 7.9 5.1 13 5.6 0.1 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) HNH PF01844.18 AEO58838.1 - 6.9 6.6 8.2 22 5.0 0.1 3.8 4 0 0 4 4 4 0 HNH endonuclease zf-BED PF02892.10 AEO58838.1 - 7.3 6.4 9.0 22 4.8 0.6 3.3 3 0 0 3 3 3 0 BED zinc finger DSBA PF01323.15 AEO58841.1 - 1.1e-15 57.6 0.0 1.3e-15 57.5 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain TFIIE_beta PF02186.10 AEO58842.1 - 0.025 14.5 0.0 0.074 13.0 0.0 1.7 1 0 0 1 1 1 0 TFIIE beta subunit core domain Dermcidin PF15291.1 AEO58842.1 - 0.04 14.1 0.5 0.04 14.1 0.4 2.2 3 0 0 3 3 3 0 Dermcidin, antibiotic peptide Speriolin_N PF15058.1 AEO58842.1 - 0.067 13.0 3.9 0.11 12.3 2.7 1.3 1 0 0 1 1 1 0 Speriolin N terminus Cyt-b5 PF00173.23 AEO58843.1 - 7.4e-26 89.7 0.1 9.6e-26 89.3 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain F-actin_cap_A PF01267.12 AEO58844.1 - 1.1e-85 286.9 0.0 1.2e-85 286.8 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Transket_pyr PF02779.19 AEO58845.1 - 5e-43 146.6 0.0 8.8e-43 145.8 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 AEO58845.1 - 6e-32 110.1 0.1 1.2e-31 109.2 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain Cellulase PF00150.13 AEO58846.1 - 1.2e-09 37.8 0.0 1.2e-09 37.8 0.0 1.5 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) TMEM154 PF15102.1 AEO58846.1 - 0.029 14.0 0.0 0.072 12.7 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family LRRC37AB_C PF14914.1 AEO58846.1 - 0.14 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain Synaptobrevin PF00957.16 AEO58846.1 - 0.14 11.7 1.0 0.22 11.1 0.7 1.3 1 0 0 1 1 1 0 Synaptobrevin DUF3357 PF11837.3 AEO58846.1 - 0.14 11.9 0.6 1 9.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) DUF1510 PF07423.6 AEO58846.1 - 0.2 11.0 2.6 0.93 8.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF1777 PF08648.7 AEO58846.1 - 2.8 7.6 49.3 0.56 9.9 22.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) Atrophin-1 PF03154.10 AEO58846.1 - 5.6 4.9 19.4 13 3.7 13.5 1.6 1 0 0 1 1 1 0 Atrophin-1 family MFS_1 PF07690.11 AEO58847.1 - 2.1e-34 118.7 30.9 2.7e-34 118.4 21.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 AEO58847.1 - 7.9e-08 30.9 1.8 1.4e-07 30.1 1.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PAS PF00989.19 AEO58848.1 - 0.0001 22.0 0.0 0.00044 19.9 0.0 2.0 2 0 0 2 2 2 1 PAS fold Zn_clus PF00172.13 AEO58848.1 - 0.0017 18.2 8.6 0.004 17.0 6.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Flavokinase PF01687.12 AEO58849.1 - 5e-35 120.0 0.0 6.1e-35 119.8 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase NAD_binding_10 PF13460.1 AEO58850.1 - 1.4e-13 51.2 0.8 1.8e-13 50.9 0.6 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 AEO58850.1 - 1.8e-10 40.6 0.0 2.4e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 AEO58850.1 - 3.2e-07 29.8 0.0 5.4e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family HIM1 PF08732.5 AEO58850.1 - 8.9e-06 24.4 0.0 2.1e-05 23.1 0.0 1.5 2 0 0 2 2 2 1 HIM1 adh_short PF00106.20 AEO58850.1 - 0.00039 20.3 1.5 0.012 15.5 1.0 2.5 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 AEO58850.1 - 0.00088 18.2 0.2 0.14 11.0 0.0 2.8 2 1 1 3 3 3 1 Male sterility protein 3Beta_HSD PF01073.14 AEO58850.1 - 0.00094 17.9 0.0 0.0013 17.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 AEO58850.1 - 0.048 13.9 0.0 0.097 12.9 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain WGG PF10273.4 AEO58851.1 - 2.2e-05 24.4 1.7 4.4e-05 23.4 1.2 1.5 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.2 AEO58851.1 - 0.011 15.8 0.2 0.011 15.8 0.1 1.9 1 1 1 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) SDA1 PF05285.7 AEO58851.1 - 0.015 14.5 5.9 0.017 14.4 4.1 1.1 1 0 0 1 1 1 0 SDA1 BSD PF03909.12 AEO58852.1 - 1.1e-13 50.7 0.2 2e-13 49.8 0.1 1.5 1 0 0 1 1 1 1 BSD domain Sigma70_r2 PF04542.9 AEO58852.1 - 0.17 11.5 1.3 0.43 10.2 0.1 2.2 2 0 0 2 2 2 0 Sigma-70 region 2 PAP1 PF08601.5 AEO58853.1 - 3.9e-52 178.0 17.4 3.9e-52 178.0 12.0 2.1 2 0 0 2 2 2 1 Transcription factor PAP1 bZIP_1 PF00170.16 AEO58853.1 - 7.8e-09 35.3 14.7 2.1e-08 34.0 10.2 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 AEO58853.1 - 0.0026 17.5 16.9 0.009 15.8 11.7 1.9 1 1 0 1 1 1 1 Basic region leucine zipper DUF904 PF06005.7 AEO58853.1 - 0.003 17.8 6.7 0.0082 16.4 4.7 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF904) Ead_Ea22 PF13935.1 AEO58853.1 - 0.0048 17.2 0.3 0.023 15.0 0.0 2.1 2 0 0 2 2 2 1 Ead/Ea22-like protein Cluap1 PF10234.4 AEO58853.1 - 0.012 14.8 6.6 0.019 14.1 4.6 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 Adeno_PIX PF03955.9 AEO58853.1 - 0.022 15.2 1.5 0.022 15.2 1.0 2.2 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Dor1 PF04124.7 AEO58853.1 - 0.023 13.1 0.5 0.04 12.3 0.3 1.3 1 0 0 1 1 1 0 Dor1-like family PilJ PF13675.1 AEO58853.1 - 0.084 13.1 1.4 0.17 12.1 0.9 1.5 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term FlaC_arch PF05377.6 AEO58853.1 - 0.12 12.3 2.4 0.25 11.2 1.7 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) IncA PF04156.9 AEO58853.1 - 0.12 11.9 4.2 0.29 10.6 2.9 1.6 1 0 0 1 1 1 0 IncA protein TMPIT PF07851.8 AEO58853.1 - 0.37 9.8 1.2 0.57 9.1 0.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein Glutaredoxin2_C PF04399.8 AEO58853.1 - 0.42 10.1 2.6 0.73 9.4 1.8 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain DUF812 PF05667.6 AEO58853.1 - 0.49 8.8 9.2 0.041 12.3 2.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF812) bZIP_Maf PF03131.12 AEO58853.1 - 0.53 10.6 9.4 1.3 9.3 6.5 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor V_ATPase_I PF01496.14 AEO58853.1 - 1.5 6.5 2.6 2.1 6.1 1.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.10 AEO58853.1 - 1.8 8.0 6.1 3.6 7.1 4.2 1.5 1 0 0 1 1 1 0 Septum formation initiator Bap31 PF05529.7 AEO58853.1 - 5.2 6.4 5.9 10 5.5 4.1 1.4 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like TMF_DNA_bd PF12329.3 AEO58853.1 - 9.6 6.0 16.0 1.5 8.6 8.2 1.8 2 0 0 2 2 1 0 TATA element modulatory factor 1 DNA binding Pkinase PF00069.20 AEO58855.1 - 5.3e-60 202.7 0.2 8.9e-60 202.0 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO58855.1 - 3.6e-32 111.4 0.2 6.4e-32 110.6 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO58855.1 - 4e-05 22.7 0.0 7.5e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Med15 PF09606.5 AEO58855.1 - 0.0033 15.7 18.3 0.0041 15.3 12.7 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal APH PF01636.18 AEO58855.1 - 0.012 15.3 0.2 0.012 15.3 0.1 2.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 AEO58855.1 - 0.028 13.4 0.0 0.063 12.3 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAT1 PF09770.4 AEO58855.1 - 0.028 12.6 19.4 0.038 12.2 13.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Suf PF05843.9 AEO58855.1 - 0.11 12.2 6.8 0.15 11.7 4.7 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Pex14_N PF04695.8 AEO58855.1 - 0.26 11.3 10.6 0.48 10.4 7.4 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-RING_2 PF13639.1 AEO58857.1 - 2.5e-09 36.8 6.8 3.8e-09 36.2 4.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 AEO58857.1 - 4.1e-07 30.0 0.6 7.7e-07 29.1 0.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 AEO58857.1 - 0.00049 19.7 3.0 0.00079 19.0 2.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 AEO58857.1 - 0.00058 19.6 3.7 0.0018 18.1 2.5 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 AEO58857.1 - 0.0028 17.6 6.6 0.0044 17.0 4.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AEO58857.1 - 0.015 14.9 4.2 0.024 14.3 2.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO58857.1 - 0.055 13.1 2.7 0.11 12.2 1.9 1.5 1 1 0 1 1 1 0 zinc-RING finger domain Tmpp129 PF10272.4 AEO58857.1 - 0.22 10.2 0.9 0.32 9.6 0.6 1.4 1 0 0 1 1 1 0 Putative transmembrane protein precursor zf-Di19 PF05605.7 AEO58857.1 - 0.32 11.1 4.1 18 5.5 1.3 2.7 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_4 PF14570.1 AEO58857.1 - 0.38 10.3 6.6 11 5.6 5.3 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Rad50_zn_hook PF04423.9 AEO58857.1 - 0.5 9.8 2.0 5.2 6.6 0.2 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif Abhydrolase_3 PF07859.8 AEO58858.1 - 2.3e-39 135.1 0.1 9.7e-30 103.7 0.0 2.7 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 AEO58858.1 - 3.1e-13 49.1 0.0 1.2e-12 47.2 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) COesterase PF00135.23 AEO58858.1 - 0.00012 21.0 0.1 0.034 12.8 0.0 2.3 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_5 PF12695.2 AEO58858.1 - 0.0038 16.9 0.0 0.011 15.5 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family SR-25 PF10500.4 AEO58858.1 - 0.8 9.1 10.1 2.5 7.5 7.0 1.8 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein MRP-L27 PF09809.4 AEO58859.1 - 1.5e-16 60.0 0.2 2e-16 59.6 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Utp14 PF04615.8 AEO58860.1 - 1.8e-187 624.8 53.1 1.8e-187 624.8 36.8 2.2 1 1 1 2 2 2 1 Utp14 protein DHBP_synthase PF00926.14 AEO58861.1 - 1.7e-74 249.2 0.0 7.3e-74 247.1 0.0 1.7 1 1 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Methyltransf_23 PF13489.1 AEO58862.1 - 1.6e-20 73.4 0.0 2.5e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO58862.1 - 1.8e-15 57.1 0.0 2.9e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO58862.1 - 4.5e-13 49.7 0.0 7.3e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO58862.1 - 6.8e-12 45.2 0.0 1.3e-11 44.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO58862.1 - 1.2e-11 44.9 0.0 4.4e-11 43.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO58862.1 - 1.8e-06 27.9 2.3 2.8e-06 27.3 0.4 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO58862.1 - 2.1e-05 24.7 0.0 3.4e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 AEO58862.1 - 0.00041 19.5 0.0 0.00076 18.6 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 AEO58862.1 - 0.00051 19.2 0.0 0.0058 15.7 0.0 2.0 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 AEO58862.1 - 0.00072 18.9 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.6 AEO58862.1 - 0.083 11.5 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) PBP1_TM PF14812.1 AEO58865.1 - 1.7 8.9 9.0 1.4 9.3 3.2 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BCS1_N PF08740.6 AEO58867.1 - 2.8e-19 69.4 0.1 2.8e-19 69.4 0.1 3.1 2 1 0 2 2 1 1 BCS1 N terminal AAA PF00004.24 AEO58867.1 - 1.7e-17 63.8 0.0 1.4e-08 35.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 AEO58867.1 - 0.00017 21.6 0.1 0.001 19.1 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 AEO58867.1 - 0.00072 20.3 1.1 0.034 14.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 AEO58867.1 - 0.00073 18.9 0.0 0.0022 17.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 AEO58867.1 - 0.0017 18.0 0.0 0.0061 16.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 AEO58867.1 - 0.0024 16.9 0.0 0.0044 16.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 AEO58867.1 - 0.0039 16.9 0.9 0.066 12.9 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 AEO58867.1 - 0.024 14.7 0.0 0.098 12.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain TFIIF_alpha PF05793.7 AEO58867.1 - 0.041 12.2 45.2 0.071 11.4 31.3 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) MIP-T3 PF10243.4 AEO58867.1 - 0.069 11.6 52.3 0.1 11.0 36.3 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Draxin PF15550.1 AEO58867.1 - 0.15 11.6 17.4 0.27 10.8 12.1 1.4 1 0 0 1 1 1 0 Draxin AAA_33 PF13671.1 AEO58867.1 - 0.65 9.8 4.5 0.25 11.2 0.1 2.6 3 2 0 3 3 3 0 AAA domain AAA_11 PF13086.1 AEO58867.1 - 3.4 7.1 22.3 1e+02 2.3 15.5 2.5 1 1 0 1 1 1 0 AAA domain SAPS PF04499.10 AEO58867.1 - 4.1 5.9 18.9 7.1 5.1 13.1 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Na_trans_assoc PF06512.8 AEO58867.1 - 8.1 6.3 25.5 15 5.4 17.7 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated HMG_CoA_synt_C PF08540.5 AEO58868.1 - 3.9e-104 348.0 0.8 1.2e-103 346.4 0.6 1.7 1 1 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 AEO58868.1 - 3.2e-95 316.5 0.3 5.5e-95 315.8 0.2 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal PTCB-BRCT PF12738.2 AEO58869.1 - 2.4e-30 104.1 0.4 2.6e-18 65.5 0.1 4.4 5 0 0 5 5 5 3 twin BRCT domain BRCT PF00533.21 AEO58869.1 - 8.1e-26 89.9 0.0 4.7e-09 36.2 0.0 5.5 6 0 0 6 6 6 3 BRCA1 C Terminus (BRCT) domain ESCRT-II PF05871.7 AEO58870.1 - 6.3e-50 168.7 0.0 8.7e-50 168.2 0.0 1.2 1 0 0 1 1 1 1 ESCRT-II complex subunit PXA PF02194.10 AEO58871.1 - 9.3e-55 185.0 0.3 9.3e-55 185.0 0.2 2.2 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.7 AEO58871.1 - 5.5e-28 97.3 0.0 1.8e-27 95.6 0.0 2.0 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.19 AEO58871.1 - 1e-20 73.6 0.4 2.6e-20 72.2 0.3 1.7 1 0 0 1 1 1 1 PX domain RGS PF00615.14 AEO58871.1 - 1e-08 35.2 0.0 4.5e-08 33.2 0.0 2.1 2 0 0 2 2 2 1 Regulator of G protein signaling domain RRM_1 PF00076.17 AEO58872.1 - 2.4e-22 78.3 0.1 1.4e-10 40.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO58872.1 - 8e-18 64.1 0.0 6.8e-08 32.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO58872.1 - 9.6e-14 50.9 0.0 3.3e-06 26.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 AEO58872.1 - 0.023 14.5 0.0 0.053 13.3 0.0 1.5 2 0 0 2 2 2 0 RNA binding motif DEAD PF00270.24 AEO58873.1 - 5.6e-41 139.8 0.1 9.2e-41 139.1 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase GST_C_2 PF13410.1 AEO58873.1 - 1.5e-08 34.4 0.1 3.8e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 AEO58873.1 - 4.8e-08 32.8 1.0 1.9e-07 30.9 0.0 2.5 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 AEO58873.1 - 8.1e-08 32.3 0.0 1.9e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 AEO58873.1 - 2.3e-06 27.5 0.0 6e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 AEO58873.1 - 4.4e-06 26.7 0.0 1.4e-05 25.1 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Helicase_C PF00271.26 AEO58873.1 - 4.6e-06 26.4 0.0 4.6e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AEO58873.1 - 6e-05 22.9 0.0 6e-05 22.9 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit GST_C_3 PF14497.1 AEO58873.1 - 0.00035 20.9 0.0 0.0013 19.1 0.0 2.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain CDC45 PF02724.9 AEO58873.1 - 0.0015 16.6 2.2 0.0026 15.8 1.5 1.3 1 0 0 1 1 1 1 CDC45-like protein Glyco_hydro_47 PF01532.15 AEO58874.1 - 4.9e-142 473.7 0.0 5.5e-142 473.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 TipAS PF07739.8 AEO58874.1 - 0.023 15.0 0.1 0.057 13.7 0.1 1.6 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain Rad10 PF03834.9 AEO58875.1 - 1.2e-30 104.9 0.0 1.8e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 AEO58875.1 - 0.0004 20.4 0.0 0.00094 19.3 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain PHA_synth_III_E PF09712.5 AEO58876.1 - 0.016 14.6 0.3 0.024 14.0 0.2 1.2 1 0 0 1 1 1 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) MR_MLE_C PF13378.1 AEO58877.1 - 7e-20 71.0 0.1 3.1e-19 68.9 0.0 2.2 3 0 0 3 3 3 1 Enolase C-terminal domain-like MR_MLE PF01188.16 AEO58877.1 - 4.1e-13 49.6 0.0 9.7e-13 48.4 0.0 1.7 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 AEO58877.1 - 9.6e-05 22.3 0.0 0.00023 21.1 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.6 AEO58877.1 - 0.002 17.1 0.0 0.0037 16.2 0.0 1.4 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus dCMP_cyt_deam_1 PF00383.17 AEO58878.1 - 8.4e-14 51.0 0.0 1.2e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region XOO_2897-deam PF14440.1 AEO58878.1 - 0.033 13.9 0.1 0.065 12.9 0.0 1.5 1 1 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase BTG PF07742.7 AEO58878.1 - 0.078 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 BTG family DnaJ PF00226.26 AEO58879.1 - 9.6e-26 89.3 1.3 9.6e-26 89.3 0.9 2.2 2 0 0 2 2 2 1 DnaJ domain RPT PF13446.1 AEO58879.1 - 0.037 13.4 0.0 0.12 11.8 0.0 1.8 1 0 0 1 1 1 0 A repeated domain in UCH-protein PSD5 PF07637.6 AEO58879.1 - 0.26 11.3 5.0 0.62 10.1 0.5 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1595) PNPase PF03726.9 AEO58879.1 - 3 8.1 15.4 2.1 8.6 0.1 4.4 4 1 0 4 4 4 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain Stn1 PF10451.4 AEO58880.1 - 1.7e-15 56.5 0.2 1.1e-14 53.8 0.2 1.8 1 1 0 1 1 1 1 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.20 AEO58880.1 - 6.7e-05 22.6 0.1 0.00017 21.3 0.0 1.7 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain Glyco_hydro_81 PF03639.8 AEO58881.1 - 1e-200 668.3 0.9 7.4e-108 361.3 6.9 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 81 Pkinase PF00069.20 AEO58882.1 - 1.5e-28 99.6 0.0 2.2e-28 99.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO58882.1 - 1.6e-15 56.8 0.0 9.4e-12 44.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 AEO58882.1 - 0.0077 15.2 0.0 0.01 14.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like GFRP PF06399.8 AEO58882.1 - 0.11 12.0 0.0 12 5.5 0.0 2.4 2 0 0 2 2 2 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) FGGY_C PF02782.11 AEO58883.1 - 6.3e-77 257.6 0.3 1.1e-76 256.8 0.2 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 AEO58883.1 - 5.4e-64 215.8 0.0 7.4e-64 215.4 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain NTP_transferase PF00483.18 AEO58884.1 - 3.2e-34 118.3 0.0 8.3e-34 116.9 0.0 1.6 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.19 AEO58884.1 - 2.6e-16 58.3 16.6 2.2e-09 36.3 1.1 4.0 1 1 3 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 AEO58884.1 - 1.9e-08 33.6 5.1 7.8e-07 28.5 0.6 3.1 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.2 AEO58884.1 - 0.015 15.3 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 MobA-like NTP transferase domain DND1_DSRM PF14709.1 AEO58885.1 - 0.00065 19.9 0.1 0.0014 18.8 0.1 1.6 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.20 AEO58885.1 - 0.0046 17.5 0.0 0.0086 16.6 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif Prenyltrans PF00432.16 AEO58886.1 - 3e-39 132.2 27.9 1.4e-08 34.1 0.6 6.2 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 AEO58886.1 - 2.6e-24 85.7 0.0 2.7e-16 59.9 0.0 4.2 2 1 2 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 AEO58886.1 - 1.3e-05 25.1 0.0 0.00089 19.2 0.0 2.9 2 1 0 2 2 2 1 Prenyltransferase-like Zn_clus PF00172.13 AEO58887.1 - 0.0031 17.3 7.7 0.0068 16.2 5.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ubiquitin PF00240.18 AEO58888.1 - 2.8e-133 433.4 22.1 4.4e-33 112.4 0.6 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.3 AEO58888.1 - 9.2e-79 259.1 20.9 2.3e-19 68.8 0.5 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 AEO58888.1 - 2e-23 82.4 10.9 0.00018 21.6 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain Telomere_Sde2 PF13019.1 AEO58888.1 - 4.9e-22 78.3 1.0 0.00059 19.5 0.0 4.0 4 0 0 4 4 4 4 Telomere stability and silencing Rad60-SLD_2 PF13881.1 AEO58888.1 - 4.1e-14 52.4 5.1 0.07 13.0 0.0 4.9 4 3 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 AEO58888.1 - 1.8e-12 47.2 1.7 0.24 11.6 0.0 4.2 1 1 3 4 4 4 4 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 AEO58888.1 - 1.5e-10 41.0 0.0 1.5 8.8 0.0 4.6 4 0 0 4 4 4 4 Protein of unknown function (DUF2870) Methyltrans_RNA PF04452.9 AEO58888.1 - 1.4e-06 27.6 1.1 1.1 8.3 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase DUF3221 PF11518.3 AEO58888.1 - 4.1e-06 26.4 2.9 7.8 6.2 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3221) TUG-UBL1 PF11470.3 AEO58888.1 - 9.9e-06 25.3 5.5 5.9 6.8 0.0 4.2 4 0 0 4 4 4 3 GLUT4 regulating protein TUG ACT_4 PF13291.1 AEO58888.1 - 0.00035 20.8 1.0 60 4.0 0.0 4.2 4 0 0 4 4 4 0 ACT domain UN_NPL4 PF11543.3 AEO58888.1 - 0.0014 18.8 2.5 37 4.6 0.0 4.3 4 0 0 4 4 4 0 Nuclear pore localisation protein NPL4 Tash_PEST PF07708.6 AEO58888.1 - 0.0026 17.5 14.1 9.7 6.2 0.2 4.5 4 0 0 4 4 4 0 Tash protein PEST motif Plexin_cytopl PF08337.7 AEO58888.1 - 0.0028 16.0 13.3 2.8 6.1 0.2 5.6 5 3 0 5 5 5 3 Plexin cytoplasmic RasGAP domain DUF3861 PF12977.2 AEO58888.1 - 0.0044 17.0 6.0 38 4.4 0.0 4.4 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) DUF2812 PF11193.3 AEO58888.1 - 0.0047 17.0 0.3 43 4.2 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2812) GABP-alpha PF11620.3 AEO58888.1 - 0.0053 16.7 5.8 36 4.4 0.0 4.0 4 0 0 4 4 4 0 GA-binding protein alpha chain Sortase PF04203.8 AEO58888.1 - 0.0086 15.6 2.9 24 4.5 0.0 3.8 2 1 1 4 4 4 0 Sortase family Carot_N PF09150.5 AEO58888.1 - 0.011 15.4 0.0 69 3.0 0.0 3.9 1 1 2 4 4 4 0 Orange carotenoid protein, N-terminal DUF3781 PF12636.2 AEO58888.1 - 0.041 13.8 7.8 52 3.8 0.1 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3781) CTDII PF01556.13 AEO58888.1 - 0.11 12.3 14.3 11 5.9 0.2 4.3 1 1 3 4 4 4 0 DnaJ C terminal domain FlgD_ig PF13860.1 AEO58888.1 - 0.15 11.7 4.2 85 2.9 0.0 4.1 4 0 0 4 4 4 0 FlgD Ig-like domain CDC48_2 PF02933.12 AEO58888.1 - 3.5 7.3 12.3 37 4.0 0.1 4.1 4 0 0 4 4 4 0 Cell division protein 48 (CDC48), domain 2 YajC PF02699.10 AEO58888.1 - 9.7 5.9 12.7 45 3.8 0.1 4.0 4 0 0 4 4 4 0 Preprotein translocase subunit FERM_N PF09379.5 AEO58888.1 - 9.9 6.2 12.4 95 3.1 0.1 5.6 4 4 0 4 4 4 0 FERM N-terminal domain BRAP2 PF07576.7 AEO58889.1 - 1.2e-18 66.6 0.0 2.4e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 AEO58889.1 - 6.7e-17 61.3 8.7 2.1e-16 59.7 6.0 1.8 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 AEO58889.1 - 3.1e-09 36.5 9.7 3.1e-09 36.5 6.7 2.0 2 0 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.1 AEO58889.1 - 0.00011 21.7 7.0 0.00011 21.7 4.8 2.3 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 AEO58889.1 - 0.00018 21.0 8.0 0.00048 19.7 5.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AEO58889.1 - 0.0024 17.5 6.7 0.0024 17.5 4.6 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AEO58889.1 - 0.004 17.1 8.6 0.004 17.1 6.0 2.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 AEO58889.1 - 0.0046 17.0 5.8 0.0046 17.0 4.0 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_6 PF14835.1 AEO58889.1 - 0.0065 16.2 3.0 0.015 15.0 2.1 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 AEO58889.1 - 0.028 14.1 4.2 0.051 13.2 1.1 2.5 1 1 1 2 2 2 0 RING-type zinc-finger Vps53_N PF04100.7 AEO58889.1 - 0.33 9.6 5.1 0.5 9.0 3.5 1.3 1 0 0 1 1 1 0 Vps53-like, N-terminal Ribosomal_L11_N PF03946.9 AEO58889.1 - 0.98 8.9 2.7 2 7.9 1.9 1.5 1 0 0 1 1 1 0 Ribosomal protein L11, N-terminal domain Acyltransferase PF01553.16 AEO58890.1 - 2.5e-10 39.9 0.0 5.4e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 Acyltransferase Suc_Fer-like PF06999.7 AEO58891.1 - 3.7e-34 118.7 0.0 7.8e-33 114.4 0.0 2.5 1 1 0 1 1 1 1 Sucrase/ferredoxin-like Nop14 PF04147.7 AEO58891.1 - 0.0029 15.6 13.2 0.0038 15.2 9.1 1.1 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.9 AEO58891.1 - 0.0092 14.0 8.9 0.013 13.6 6.1 1.1 1 0 0 1 1 1 1 CDC45-like protein FAM176 PF14851.1 AEO58891.1 - 0.035 13.7 4.1 0.06 13.0 2.8 1.4 1 0 0 1 1 1 0 FAM176 family RNase_H2-Ydr279 PF09468.5 AEO58891.1 - 0.047 12.8 1.4 0.061 12.5 1.0 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) BSP_II PF05432.6 AEO58891.1 - 0.084 12.1 22.6 0.16 11.2 15.6 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DDHD PF02862.12 AEO58891.1 - 0.12 12.1 3.2 0.18 11.5 2.2 1.2 1 0 0 1 1 1 0 DDHD domain Daxx PF03344.10 AEO58891.1 - 0.14 10.6 20.8 0.2 10.1 14.4 1.1 1 0 0 1 1 1 0 Daxx Family Zip PF02535.17 AEO58891.1 - 0.14 11.1 2.5 0.21 10.5 1.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Nucleoplasmin PF03066.10 AEO58891.1 - 0.19 11.2 17.8 0.31 10.5 12.3 1.3 1 0 0 1 1 1 0 Nucleoplasmin HSP90 PF00183.13 AEO58891.1 - 0.25 9.7 17.2 0.33 9.3 11.9 1.1 1 0 0 1 1 1 0 Hsp90 protein Tom37_C PF11801.3 AEO58891.1 - 0.3 10.9 1.3 0.45 10.3 0.9 1.3 1 0 0 1 1 1 0 Tom37 C-terminal domain Paf1 PF03985.8 AEO58891.1 - 0.36 9.5 24.8 0.47 9.1 17.2 1.1 1 0 0 1 1 1 0 Paf1 Peptidase_C37 PF05416.7 AEO58891.1 - 0.42 8.8 3.2 0.57 8.4 2.2 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase TRAP_alpha PF03896.11 AEO58891.1 - 0.7 8.8 9.7 1 8.3 6.7 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF3899 PF13038.1 AEO58891.1 - 1.1 9.5 2.6 1.9 8.6 1.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) RXT2_N PF08595.6 AEO58891.1 - 1.2 8.9 9.5 1.9 8.2 6.6 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Myc_N PF01056.13 AEO58891.1 - 1.3 8.0 11.1 2.2 7.3 7.7 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Prog_receptor PF02161.10 AEO58891.1 - 1.3 7.7 8.4 2.2 6.9 5.8 1.3 1 0 0 1 1 1 0 Progesterone receptor CENP-T PF15511.1 AEO58891.1 - 2.1 7.4 13.0 3.3 6.8 9.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T YqfQ PF14181.1 AEO58891.1 - 2.4 8.1 15.3 5 7.1 10.6 1.5 1 0 0 1 1 1 0 YqfQ-like protein TraH_2 PF06871.6 AEO58891.1 - 2.5 7.4 8.4 5.6 6.3 5.8 1.6 1 0 0 1 1 1 0 TraH_2 Usp PF00582.21 AEO58891.1 - 2.6 8.2 5.0 4.9 7.3 3.4 1.5 1 0 0 1 1 1 0 Universal stress protein family RNA_polI_A34 PF08208.6 AEO58891.1 - 2.8 7.5 17.9 4.3 6.9 12.4 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Pox_Ag35 PF03286.9 AEO58891.1 - 2.9 7.3 16.2 4.9 6.6 11.3 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Tim54 PF11711.3 AEO58891.1 - 3.3 6.2 9.0 5.9 5.3 6.2 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RR_TM4-6 PF06459.7 AEO58891.1 - 4 7.2 14.1 6 6.6 9.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MIP-T3 PF10243.4 AEO58891.1 - 5 5.4 21.4 7.4 4.9 14.9 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1510 PF07423.6 AEO58891.1 - 7.3 5.8 20.9 11 5.3 14.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RRN3 PF05327.6 AEO58891.1 - 7.5 4.5 8.7 11 3.9 6.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Drf_GBD PF06371.8 AEO58892.1 - 5.1e-14 52.0 2.0 2.1e-12 46.8 1.4 2.6 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain Pex14_N PF04695.8 AEO58892.1 - 0.07 13.1 6.8 0.62 10.1 2.5 3.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SSP160 PF06933.6 AEO58892.1 - 0.67 7.8 12.2 1.2 7.0 8.4 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mucin PF01456.12 AEO58892.1 - 4.3 7.1 16.3 0.31 10.8 6.1 2.5 2 0 0 2 2 2 0 Mucin-like glycoprotein Dicty_REP PF05086.7 AEO58892.1 - 7.3 4.2 7.5 12 3.5 5.2 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein WWbp PF10349.4 AEO58894.1 - 7.9e-15 55.7 12.5 1.1e-14 55.2 8.7 1.2 1 0 0 1 1 1 1 WW-domain ligand protein UCR_hinge PF02320.11 AEO58895.1 - 1.1e-27 95.7 7.7 2.5e-27 94.6 5.3 1.6 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein CDC45 PF02724.9 AEO58895.1 - 0.3 9.0 6.5 0.31 9.0 4.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Mnd1 PF03962.10 AEO58895.1 - 0.86 9.2 10.6 1 8.9 7.4 1.2 1 0 0 1 1 1 0 Mnd1 family Bud13 PF09736.4 AEO58895.1 - 1.5 9.0 8.0 1.9 8.7 5.6 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Merozoite_SPAM PF07133.6 AEO58895.1 - 2 8.2 20.4 2.7 7.8 14.2 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) EBV-NA3 PF05009.7 AEO58895.1 - 2.4 7.3 11.1 3.2 6.9 7.7 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) DUF2052 PF09747.4 AEO58895.1 - 3.2 7.6 15.1 4.7 7.0 10.5 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Pox_Ag35 PF03286.9 AEO58895.1 - 3.2 7.2 13.6 4.4 6.7 9.4 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Prothymosin PF03247.9 AEO58895.1 - 3.5 7.8 26.8 5 7.3 18.6 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family GET2 PF08690.5 AEO58895.1 - 4 6.5 5.5 5.2 6.2 3.8 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 SAPS PF04499.10 AEO58895.1 - 5.1 5.6 8.0 5.6 5.4 5.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DDHD PF02862.12 AEO58895.1 - 6.1 6.5 6.9 6.6 6.4 4.8 1.2 1 0 0 1 1 1 0 DDHD domain RRN3 PF05327.6 AEO58895.1 - 7.6 4.5 8.0 8.6 4.3 5.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Tim54 PF11711.3 AEO58895.1 - 8 4.9 13.7 9.4 4.7 9.5 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Spore_coat_CotO PF14153.1 AEO58895.1 - 8.7 5.7 17.9 13 5.2 12.4 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Asp-B-Hydro_N PF05279.6 AEO58895.1 - 8.7 6.1 21.2 11 5.8 14.7 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Daxx PF03344.10 AEO58895.1 - 8.9 4.6 20.9 10 4.4 14.5 1.0 1 0 0 1 1 1 0 Daxx Family HSP70 PF00012.15 AEO58895.1 - 9.4 4.0 12.5 11 3.7 8.6 1.0 1 0 0 1 1 1 0 Hsp70 protein MFS_1 PF07690.11 AEO58897.1 - 2.6e-22 79.0 37.9 2.6e-22 79.0 26.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 AEO58897.1 - 0.01 15.6 0.1 0.036 13.8 0.1 1.9 1 0 0 1 1 1 0 MFS_1 like family adh_short PF00106.20 AEO58898.1 - 0.043 13.7 0.1 0.2 11.5 0.0 2.1 2 0 0 2 2 2 0 short chain dehydrogenase Acetyltransf_1 PF00583.19 AEO58900.1 - 1.2e-11 44.4 0.0 2.5e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AEO58900.1 - 2.4e-10 40.4 0.1 7.5e-10 38.8 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 AEO58900.1 - 4.6e-10 39.6 0.0 2.5e-07 30.8 0.0 2.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Fungal_trans_2 PF11951.3 AEO58900.1 - 1.8e-05 23.5 1.5 2.8e-05 22.8 1.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FR47 PF08445.5 AEO58900.1 - 4.7e-05 23.0 0.0 9.2e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 AEO58900.1 - 0.0001 22.1 0.0 0.00022 21.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 AEO58900.1 - 0.0019 18.0 0.0 0.0062 16.4 0.0 1.8 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.1 AEO58900.1 - 0.0085 16.2 0.0 0.028 14.5 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 AEO58900.1 - 0.017 14.9 0.0 0.09 12.6 0.0 2.3 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain TctC PF03401.9 AEO58900.1 - 0.23 10.3 0.0 0.41 9.5 0.0 1.3 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter family receptor Fungal_trans PF04082.13 AEO58901.1 - 3.7e-25 88.2 0.0 6.5e-25 87.4 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO58901.1 - 0.0045 16.8 3.0 0.0087 15.9 2.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 AEO58902.1 - 3.8e-40 137.6 58.3 2.6e-38 131.6 39.8 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily RXT2_N PF08595.6 AEO58903.1 - 9.8e-16 57.8 1.0 1.5e-15 57.3 0.0 1.7 2 0 0 2 2 2 1 RXT2-like, N-terminal SKG6 PF08693.5 AEO58904.1 - 3.2e-09 35.9 2.6 6.2e-09 35.0 1.8 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.1 AEO58904.1 - 0.0014 18.3 0.1 0.004 16.8 0.1 1.7 1 0 0 1 1 1 1 TMEM154 protein family DUF4448 PF14610.1 AEO58904.1 - 0.017 14.6 0.0 0.038 13.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) IncA PF04156.9 AEO58904.1 - 0.33 10.5 0.0 0.55 9.8 0.0 1.3 1 0 0 1 1 1 0 IncA protein Glyco_hydro_16 PF00722.16 AEO58905.1 - 5.3e-46 156.2 0.5 9.7e-46 155.3 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Sporozoite_P67 PF05642.6 AEO58905.1 - 0.06 11.2 11.7 0.098 10.5 8.1 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DHDPS PF00701.17 AEO58907.1 - 1.1e-39 135.7 0.0 7.7e-29 100.2 0.0 2.0 1 1 1 2 2 2 2 Dihydrodipicolinate synthetase family HTH_29 PF13551.1 AEO58907.1 - 0.021 14.9 0.0 0.95 9.6 0.0 2.5 2 0 0 2 2 2 0 Winged helix-turn helix DUF3446 PF11928.3 AEO58907.1 - 0.025 14.7 15.7 0.027 14.6 5.4 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3446) DUF3774 PF12609.3 AEO58907.1 - 1.3 9.9 9.2 3 8.7 6.3 1.6 1 0 0 1 1 1 0 Wound-induced protein Bac_chlorC PF02043.12 AEO58907.1 - 3.1 7.6 5.3 6.7 6.5 1.6 2.4 2 0 0 2 2 2 0 Bacteriochlorophyll C binding protein Macoilin PF09726.4 AEO58907.1 - 4.8 5.3 6.0 6.5 4.8 4.2 1.1 1 0 0 1 1 1 0 Transmembrane protein RAP1 PF07218.6 AEO58907.1 - 7.6 4.4 4.8 9.6 4.1 3.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) GFO_IDH_MocA PF01408.17 AEO58908.1 - 9.4e-11 42.2 0.0 1.9e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Dfp1_Him1_M PF08630.5 AEO58909.1 - 7.3e-42 142.0 0.0 1.5e-41 141.0 0.0 1.5 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 AEO58909.1 - 2.4e-25 87.9 0.4 3.8e-25 87.2 0.3 1.3 1 0 0 1 1 1 1 DBF zinc finger DUF1777 PF08648.7 AEO58909.1 - 0.003 17.3 10.0 0.003 17.3 6.9 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF1777) PTCB-BRCT PF12738.2 AEO58909.1 - 0.0059 16.4 0.0 0.018 14.8 0.0 1.8 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.21 AEO58909.1 - 0.016 15.3 0.0 0.038 14.1 0.0 1.8 1 1 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain DUF3439 PF11921.3 AEO58909.1 - 0.13 11.9 1.0 0.32 10.7 0.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Peptidase_M24 PF00557.19 AEO58910.1 - 1.4e-47 162.0 0.1 1.9e-47 161.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 AEO58910.1 - 1.7e-35 121.2 0.0 3.4e-35 120.3 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain BASP1 PF05466.7 AEO58910.1 - 7.1 6.3 6.5 10 5.8 4.5 1.1 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) HLH PF00010.21 AEO58911.1 - 8.9e-17 60.5 0.5 6.2e-16 57.8 0.1 2.3 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain APG12 PF04110.8 AEO58912.1 - 7e-26 90.2 0.0 8.7e-26 89.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 AEO58912.1 - 7.8e-05 22.5 0.0 9.5e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Pantoate_transf PF02548.10 AEO58913.1 - 4.2e-70 235.8 0.1 5.1e-70 235.5 0.1 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase UQ_con PF00179.21 AEO58914.1 - 2.8e-37 127.2 0.0 3.5e-37 126.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF572 PF04502.8 AEO58915.1 - 5.2e-53 180.3 0.0 6.3e-53 180.0 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) Peptidase_M32 PF02074.10 AEO58915.1 - 0.14 10.7 0.3 0.2 10.2 0.2 1.1 1 0 0 1 1 1 0 Carboxypeptidase Taq (M32) metallopeptidase DUF2526 PF10735.4 AEO58915.1 - 0.32 11.0 4.6 0.25 11.3 1.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2526) Glyco_hydro_43 PF04616.9 AEO58916.1 - 1.7e-67 227.4 6.8 2.2e-67 227.1 4.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 PD40 PF07676.7 AEO58916.1 - 3.1 7.5 7.5 0.64 9.7 0.1 3.5 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat p450 PF00067.17 AEO58917.1 - 1.1e-30 106.5 0.0 1.8e-30 105.9 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 DRMBL PF07522.9 AEO58918.1 - 2.8e-07 30.5 0.0 7e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 AEO58918.1 - 1.7e-05 24.4 0.0 3.7e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.7 AEO58918.1 - 0.0053 16.5 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Cys_rich_VLP PF14194.1 AEO58918.1 - 0.13 12.0 0.1 0.34 10.6 0.1 1.7 1 0 0 1 1 1 0 Cysteine-rich VLP Glyco_hydro_32N PF00251.15 AEO58919.1 - 0.045 13.0 0.0 0.11 11.8 0.0 1.7 1 1 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain Velvet PF11754.3 AEO58920.1 - 5.9e-48 163.1 0.0 1.1e-47 162.3 0.0 1.4 1 0 0 1 1 1 1 Velvet factor Glyco_hydro_61 PF03443.9 AEO58921.1 - 2.9e-85 285.5 1.4 3.9e-85 285.1 0.2 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 Herpes_capsid PF06112.6 AEO58921.1 - 1.4 8.9 5.6 2.6 8.0 3.8 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein YTH PF04146.10 AEO58923.1 - 1.5e-39 134.7 0.0 2.3e-39 134.2 0.0 1.3 1 0 0 1 1 1 1 YT521-B-like domain DUF2456 PF10445.4 AEO58924.1 - 6.6e-09 35.5 2.4 7.5e-09 35.3 0.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2456) SR-25 PF10500.4 AEO58924.1 - 2.2 7.6 7.1 2.9 7.2 4.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Mannosyl_trans2 PF04188.8 AEO58925.1 - 4.6e-61 207.0 0.1 9e-61 206.1 0.1 1.4 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V)) BNR PF02012.15 AEO58927.1 - 2.4e-17 59.8 16.2 0.22 11.4 0.5 9.7 8 0 0 8 8 8 5 BNR/Asp-box repeat Kelch_4 PF13418.1 AEO58927.1 - 0.0028 17.3 0.2 0.33 10.7 0.0 3.1 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_6 PF13964.1 AEO58927.1 - 0.0037 17.3 0.0 8 6.8 0.0 3.9 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 AEO58927.1 - 0.028 14.6 10.1 0.42 10.8 0.1 4.9 5 0 0 5 5 5 0 Galactose oxidase, central domain PTCRA PF15028.1 AEO58927.1 - 0.065 12.7 0.4 0.19 11.2 0.3 1.7 1 0 0 1 1 1 0 Pre-T-cell antigen receptor Corona_nucleoca PF00937.13 AEO58927.1 - 0.12 11.2 0.8 0.24 10.3 0.6 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Hira PF07569.6 AEO58928.1 - 4.9e-85 284.2 0.0 1.6e-84 282.4 0.0 1.9 2 1 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.27 AEO58928.1 - 6e-39 130.5 22.0 7.2e-07 28.8 0.1 8.5 8 0 0 8 8 8 7 WD domain, G-beta repeat HIRA_B PF09453.5 AEO58928.1 - 9.9e-11 40.8 0.6 2e-10 39.9 0.4 1.6 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.7 AEO58928.1 - 0.0027 17.3 2.5 38 4.0 0.0 5.2 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Mucin PF01456.12 AEO58928.1 - 0.16 11.7 17.5 0.56 9.9 12.1 1.9 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.3 AEO58928.1 - 0.23 11.1 11.7 0.45 10.2 8.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) IKI3 PF04762.7 AEO58928.1 - 0.46 8.2 0.1 2.3 5.9 0.0 2.1 3 0 0 3 3 3 0 IKI3 family SSP160 PF06933.6 AEO58928.1 - 0.49 8.3 13.3 0.74 7.7 9.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Dicty_REP PF05086.7 AEO58928.1 - 3.1 5.4 1.8 4.6 4.8 1.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RdRP_3 PF00998.18 AEO58929.1 - 4.2 5.7 8.7 4.2 5.7 6.0 1.0 1 0 0 1 1 1 0 Viral RNA dependent RNA polymerase Peptidase_M24 PF00557.19 AEO58930.1 - 4.1e-43 147.3 0.0 5.8e-43 146.8 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 YL1 PF05764.8 AEO58930.1 - 0.023 14.3 4.2 0.034 13.7 2.9 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.7 AEO58930.1 - 0.06 11.2 6.1 0.081 10.8 4.2 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 AEO58930.1 - 0.094 10.7 5.3 0.12 10.3 3.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Spt5_N PF11942.3 AEO58930.1 - 0.45 11.1 10.0 1.1 9.9 7.0 1.5 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Nop53 PF07767.6 AEO58930.1 - 7.6 5.4 11.8 8.1 5.3 7.8 1.3 1 1 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SBP56 PF05694.6 AEO58931.1 - 3.9e-07 28.9 0.0 9.5e-05 21.0 0.0 2.6 2 1 0 2 2 2 2 56kDa selenium binding protein (SBP56) Lactonase PF10282.4 AEO58931.1 - 0.00023 20.3 0.2 1.8 7.5 0.0 3.0 2 1 1 3 3 3 2 Lactonase, 7-bladed beta-propeller NHL PF01436.16 AEO58931.1 - 0.0038 17.1 0.1 0.58 10.2 0.0 3.5 4 0 0 4 4 4 1 NHL repeat SGL PF08450.7 AEO58931.1 - 0.01 15.2 0.0 2.8 7.2 0.0 3.4 4 0 0 4 4 4 0 SMP-30/Gluconolaconase/LRE-like region DUF1513 PF07433.6 AEO58931.1 - 0.03 13.2 0.1 21 3.8 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1513) Nup160 PF11715.3 AEO58931.1 - 0.18 9.9 0.0 0.23 9.5 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Acetyltransf_1 PF00583.19 AEO58932.1 - 3.6e-07 30.1 0.0 5.9e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AEO58932.1 - 5.6e-07 29.6 0.0 1e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 AEO58932.1 - 0.0014 18.7 0.0 0.0037 17.3 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 AEO58932.1 - 0.0021 17.7 0.0 0.0037 16.9 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 AEO58932.1 - 0.0039 17.0 0.0 0.0077 16.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SspB PF04386.8 AEO58932.1 - 0.0061 16.1 0.0 0.0085 15.7 0.0 1.2 1 0 0 1 1 1 1 Stringent starvation protein B FtsJ PF01728.14 AEO58933.1 - 1.2e-60 204.6 0.0 1.5e-60 204.2 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase DEAD PF00270.24 AEO58934.1 - 2.3e-40 137.8 0.0 4.8e-40 136.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO58934.1 - 9.3e-24 83.0 0.0 1.9e-23 82.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 AEO58934.1 - 0.0007 18.4 0.0 0.001 17.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 AEO58934.1 - 0.0026 17.6 0.1 0.0067 16.2 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CENP-U PF13097.1 AEO58934.1 - 0.23 11.3 5.4 3.8 7.4 4.7 2.4 2 0 0 2 2 2 0 CENP-A nucleosome associated complex (NAC) subunit RR_TM4-6 PF06459.7 AEO58934.1 - 2.2 8.0 11.6 4.5 7.0 8.1 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Flavoprotein PF02441.14 AEO58936.1 - 2.2e-19 69.4 0.0 3.6e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Flavoprotein Ank_4 PF13637.1 AEO58936.1 - 0.087 13.3 0.0 13 6.4 0.0 3.6 2 1 2 4 4 4 0 Ankyrin repeats (many copies) Hexapep PF00132.19 AEO58937.1 - 2.1e-10 39.5 10.6 7.7e-07 28.3 1.3 3.8 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 AEO58937.1 - 0.001 18.6 11.3 0.068 12.7 0.5 3.2 1 1 1 2 2 2 2 Hexapeptide repeat of succinyl-transferase Complex1_51K PF01512.12 AEO58938.1 - 2.2e-47 160.5 0.0 3.5e-47 159.9 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 AEO58938.1 - 1.9e-17 62.1 1.0 1.9e-17 62.1 0.7 1.9 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 AEO58938.1 - 1.7e-09 37.4 0.0 5.3e-09 35.8 0.0 1.9 2 0 0 2 2 2 1 SLBB domain PEX11 PF05648.9 AEO58939.1 - 7.2e-15 54.8 0.0 1.1e-09 37.9 0.0 3.2 3 0 0 3 3 3 3 Peroxisomal biogenesis factor 11 (PEX11) DUF4381 PF14316.1 AEO58939.1 - 0.019 15.0 0.5 0.059 13.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Nucleoplasmin PF03066.10 AEO58939.1 - 0.048 13.1 0.1 0.07 12.6 0.1 1.2 1 0 0 1 1 1 0 Nucleoplasmin Sporozoite_P67 PF05642.6 AEO58939.1 - 0.11 10.2 1.4 0.13 10.0 1.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CENP-B_dimeris PF09026.5 AEO58939.1 - 1.4 9.1 5.6 2.5 8.4 3.9 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Trypan_PARP PF05887.6 AEO58939.1 - 1.9 8.2 8.5 0.085 12.6 1.1 2.0 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) PBP1_TM PF14812.1 AEO58939.1 - 4.7 7.5 7.6 0.57 10.5 2.2 1.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Synaphin PF05835.7 AEO58939.1 - 5.3 7.2 12.0 3.7 7.6 5.0 2.1 2 0 0 2 2 2 0 Synaphin protein DUF3042 PF11240.3 AEO58939.1 - 9.4 6.1 6.8 30 4.5 4.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) SRP40_C PF05022.7 AEO58940.1 - 8.2e-24 83.9 3.0 8.2e-24 83.9 2.1 2.5 3 0 0 3 3 3 1 SRP40, C-terminal domain A_deaminase PF00962.17 AEO58941.1 - 1e-40 139.7 0.0 4.3e-38 131.0 0.0 2.1 2 0 0 2 2 2 2 Adenosine/AMP deaminase A_deaminase_N PF08451.6 AEO58941.1 - 0.018 15.0 0.5 0.11 12.5 0.3 2.2 1 1 0 1 1 1 0 Adenosine/AMP deaminase N-terminal bZIP_1 PF00170.16 AEO58942.1 - 6.2e-13 48.5 2.0 8.5e-13 48.0 1.4 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 AEO58942.1 - 1.1e-06 28.2 8.3 1.9e-06 27.5 5.7 1.2 1 0 0 1 1 1 1 Basic region leucine zipper ABC_tran PF00005.22 AEO58944.1 - 2.3e-51 173.6 0.4 3.3e-24 85.7 0.0 3.1 3 0 0 3 3 3 2 ABC transporter ABC_tran_2 PF12848.2 AEO58944.1 - 9.9e-21 73.3 6.6 9.9e-21 73.3 4.5 4.0 4 1 0 4 4 3 1 ABC transporter AAA_21 PF13304.1 AEO58944.1 - 1.4e-18 67.9 0.0 1.7e-05 24.9 0.0 4.5 4 0 0 4 4 4 3 AAA domain SMC_N PF02463.14 AEO58944.1 - 4.7e-12 45.6 1.4 0.0012 18.1 0.0 4.4 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 AEO58944.1 - 1.1e-09 39.1 0.3 0.0012 19.6 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_15 PF13175.1 AEO58944.1 - 8.6e-09 34.9 1.1 0.19 10.7 0.0 4.5 4 1 0 4 4 4 3 AAA ATPase domain AAA_18 PF13238.1 AEO58944.1 - 2.1e-07 31.3 0.2 0.032 14.5 0.0 3.7 4 0 0 4 4 3 2 AAA domain DUF258 PF03193.11 AEO58944.1 - 6.1e-07 28.7 0.0 0.013 14.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 AEO58944.1 - 7.4e-07 29.6 0.0 0.0062 17.0 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 AEO58944.1 - 9.3e-07 28.2 0.1 0.011 15.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 AEO58944.1 - 9.9e-07 28.7 0.0 0.012 15.6 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_33 PF13671.1 AEO58944.1 - 3.2e-06 27.0 0.1 0.099 12.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 AEO58944.1 - 6.1e-06 26.3 2.3 0.0029 17.6 0.1 2.9 3 0 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.1 AEO58944.1 - 9.1e-06 25.8 0.1 0.19 11.8 0.0 3.1 2 2 1 3 3 2 2 AAA domain MobB PF03205.9 AEO58944.1 - 2e-05 24.2 0.4 0.19 11.4 0.2 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 AEO58944.1 - 0.00013 21.9 3.0 0.046 13.6 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA PF00004.24 AEO58944.1 - 0.00026 21.1 0.1 0.59 10.3 0.1 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ArgK PF03308.11 AEO58944.1 - 0.00027 19.8 1.0 0.31 9.7 0.1 2.7 2 0 0 2 2 2 2 ArgK protein AAA_23 PF13476.1 AEO58944.1 - 0.00048 20.4 17.7 0.038 14.3 0.0 4.8 5 0 0 5 5 5 2 AAA domain AAA_14 PF13173.1 AEO58944.1 - 0.0009 19.1 0.0 1.6 8.6 0.0 3.0 3 0 0 3 3 2 1 AAA domain Dynamin_N PF00350.18 AEO58944.1 - 0.0014 18.4 7.9 0.3 10.8 0.0 4.0 3 1 1 4 4 4 2 Dynamin family NACHT PF05729.7 AEO58944.1 - 0.0014 18.2 0.1 2.3 7.8 0.0 2.7 2 0 0 2 2 2 2 NACHT domain RNA_helicase PF00910.17 AEO58944.1 - 0.0039 17.3 0.0 2.1 8.5 0.0 2.6 2 0 0 2 2 2 1 RNA helicase SbcCD_C PF13558.1 AEO58944.1 - 0.0045 16.8 0.4 5.9 6.8 0.3 3.7 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit NTPase_1 PF03266.10 AEO58944.1 - 0.0058 16.3 0.1 1.1 8.8 0.1 2.8 2 0 0 2 2 2 1 NTPase cobW PF02492.14 AEO58944.1 - 0.0065 15.9 0.6 1.7 8.0 0.4 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ATP-synt_ab PF00006.20 AEO58944.1 - 0.011 15.2 0.1 0.81 9.1 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.1 AEO58944.1 - 0.012 15.0 0.0 6.3 6.1 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_10 PF12846.2 AEO58944.1 - 0.017 14.5 2.0 3.7 6.8 0.0 3.9 5 0 0 5 5 5 0 AAA-like domain NB-ARC PF00931.17 AEO58944.1 - 0.025 13.4 0.1 5.6 5.7 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain AAA_5 PF07728.9 AEO58944.1 - 0.025 14.2 0.2 5.1 6.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) GTP_EFTU PF00009.22 AEO58944.1 - 0.031 13.7 2.0 6.2 6.2 0.0 3.1 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain SRP54 PF00448.17 AEO58944.1 - 0.051 13.0 1.4 3.1 7.2 0.0 3.2 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain Arf PF00025.16 AEO58944.1 - 0.059 12.6 0.1 1.5 8.0 0.0 2.6 2 0 0 2 2 2 0 ADP-ribosylation factor family Halo_GVPC PF05465.8 AEO58944.1 - 0.065 13.1 1.4 0.14 12.1 0.2 2.2 2 0 0 2 2 1 0 Halobacterial gas vesicle protein C (GVPC) repeat PduV-EutP PF10662.4 AEO58944.1 - 0.1 12.0 0.1 16 4.9 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 AEO58944.1 - 0.21 11.0 0.9 24 4.3 0.0 2.8 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein Tubulin PF00091.20 AEO58945.1 - 2.7e-70 236.5 0.0 4.6e-70 235.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 AEO58945.1 - 3.5e-49 166.0 0.1 5.4e-49 165.4 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 AEO58945.1 - 9.5e-06 25.6 0.0 2e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 AEO58945.1 - 0.003 17.0 0.0 0.005 16.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain bZIP_1 PF00170.16 AEO58947.1 - 1.4e-05 24.9 7.4 2.5e-05 24.1 5.1 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 AEO58947.1 - 0.0015 18.2 7.6 0.0027 17.5 5.3 1.3 1 0 0 1 1 1 1 Basic region leucine zipper MCM2_N PF12619.3 AEO58947.1 - 0.062 13.2 3.4 0.093 12.7 2.3 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance protein 2 SR-25 PF10500.4 AEO58947.1 - 0.26 10.7 16.5 0.24 10.8 9.7 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein bZIP_Maf PF03131.12 AEO58947.1 - 1 9.6 11.0 1.7 8.9 7.6 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor Mito_fiss_reg PF05308.6 AEO58947.1 - 2 7.7 14.9 0.029 13.7 4.1 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator TPR_MLP1_2 PF07926.7 AEO58949.1 - 2.6e-30 104.8 30.3 2.6e-30 104.8 21.0 19.1 8 6 7 16 16 16 4 TPR/MLP1/MLP2-like protein CALCOCO1 PF07888.6 AEO58949.1 - 0.00011 20.7 29.5 0.00011 20.7 20.5 11.7 4 2 6 10 10 10 3 Calcium binding and coiled-coil domain (CALCOCO1) like Squash PF00299.13 AEO58950.1 - 0.038 13.8 6.0 3.8 7.3 0.1 3.5 3 0 0 3 3 3 0 Squash family serine protease inhibitor DOPA_dioxygen PF08883.6 AEO58951.1 - 6.1e-30 103.3 0.0 4.2e-29 100.6 0.0 1.9 1 1 0 1 1 1 1 Dopa 4,5-dioxygenase family Terpene_synth_C PF03936.11 AEO58952.1 - 7.1e-07 28.7 0.0 1.1e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain WD40 PF00400.27 AEO58954.1 - 1.6e-48 160.8 21.6 5.8e-12 44.9 0.1 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 AEO58954.1 - 5.7e-06 26.1 10.1 0.0096 15.6 0.2 3.9 2 2 3 5 5 5 2 Transcription factor IIIC subunit delta N-term YmzC PF14157.1 AEO58954.1 - 0.00059 19.6 0.0 0.11 12.3 0.0 3.3 4 0 0 4 4 4 1 YmzC-like protein Kelch_6 PF13964.1 AEO58954.1 - 0.016 15.3 0.7 0.21 11.8 0.0 3.1 4 0 0 4 4 4 0 Kelch motif IKI3 PF04762.7 AEO58954.1 - 0.18 9.6 3.1 0.46 8.2 0.0 2.1 2 0 0 2 2 2 0 IKI3 family GSDH PF07995.6 AEO58955.1 - 1.7e-08 33.9 0.1 4.3e-07 29.3 0.0 2.5 2 1 0 2 2 2 1 Glucose / Sorbosone dehydrogenase SGL PF08450.7 AEO58955.1 - 0.0051 16.2 0.0 0.14 11.4 0.0 2.2 2 0 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 AEO58955.1 - 0.04 13.8 0.0 11 6.1 0.0 3.7 3 1 0 3 3 3 0 NHL repeat DUF1604 PF07713.8 AEO58957.1 - 1.1e-26 92.3 0.7 5.3e-26 90.2 0.5 2.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1604) G-patch PF01585.18 AEO58957.1 - 6.9e-07 28.9 1.1 6.9e-07 28.9 0.7 2.3 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 AEO58957.1 - 0.009 15.8 7.2 0.017 14.9 1.9 3.4 2 2 0 2 2 2 1 DExH-box splicing factor binding site Pkinase PF00069.20 AEO58958.1 - 1.2e-75 254.0 0.0 1.8e-75 253.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO58958.1 - 6.7e-38 130.2 0.0 1.3e-37 129.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 AEO58958.1 - 7.7e-17 60.4 0.1 1.3e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 AEO58958.1 - 6.3e-07 28.6 0.1 1.1e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 AEO58958.1 - 0.00023 20.2 0.0 0.00035 19.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AEO58958.1 - 0.00082 19.1 0.1 0.0043 16.8 0.1 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family WaaY PF06176.6 AEO58958.1 - 0.008 15.4 0.1 0.013 14.7 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) YrbL-PhoP_reg PF10707.4 AEO58958.1 - 0.026 13.8 0.0 0.053 12.8 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.17 AEO58958.1 - 0.029 13.7 0.1 0.056 12.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.15 AEO58958.1 - 0.05 13.1 0.1 0.088 12.3 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase BNR_2 PF13088.1 AEO58960.1 - 1.5e-33 116.2 0.2 1.9e-33 115.9 0.1 1.1 1 0 0 1 1 1 1 BNR repeat-like domain BNR_3 PF13859.1 AEO58960.1 - 1.1e-08 34.5 0.0 1.6e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 BNR repeat-like domain PhoD PF09423.5 AEO58961.1 - 7.8e-149 496.0 4.2 9.2e-149 495.8 2.9 1.0 1 0 0 1 1 1 1 PhoD-like phosphatase Uteroglobin PF01099.12 AEO58962.1 - 0.063 13.0 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Uteroglobin family Macoilin PF09726.4 AEO58962.1 - 7.9 4.6 14.3 15 3.6 9.9 1.4 1 0 0 1 1 1 0 Transmembrane protein DUF2014 PF09427.5 AEO58963.1 - 1.9e-108 361.5 5.6 2.9e-108 360.9 3.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.21 AEO58963.1 - 3e-17 62.0 0.8 5.9e-17 61.1 0.5 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Glucosamine_iso PF01182.15 AEO58964.1 - 2.2e-26 92.7 0.0 3.7e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase HAD_2 PF13419.1 AEO58964.1 - 0.16 12.1 0.0 0.34 11.1 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Hexokinase_2 PF03727.11 AEO58966.1 - 2.1e-35 122.0 0.0 4.3e-28 98.1 0.0 2.2 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 AEO58966.1 - 2.1e-29 102.3 0.0 3e-29 101.8 0.0 1.2 1 0 0 1 1 1 1 Hexokinase NDT80_PhoG PF05224.7 AEO58967.1 - 1.1e-30 107.0 0.0 1.9e-30 106.2 0.0 1.4 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Glyco_hydro_3 PF00933.16 AEO58968.1 - 3.6e-56 190.3 0.0 9.3e-56 188.9 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 AEO58968.1 - 0.00015 21.4 0.0 0.00029 20.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_1 PF00583.19 AEO58968.1 - 0.00092 19.1 0.1 0.008 16.1 0.0 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AEO58968.1 - 0.031 14.4 0.0 0.083 13.0 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Fe_hyd_SSU PF02256.12 AEO58968.1 - 0.1 12.6 0.0 10 6.2 0.0 2.7 2 0 0 2 2 2 0 Iron hydrogenase small subunit Acetyltransf_10 PF13673.1 AEO58968.1 - 0.12 12.5 0.0 0.38 10.8 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Amidohydro_4 PF13147.1 AEO58969.1 - 2.6e-12 47.3 0.0 3.1e-05 24.1 0.1 2.7 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 AEO58969.1 - 1.3e-09 38.2 0.0 5.2e-09 36.2 0.0 1.9 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 AEO58969.1 - 1.8e-07 30.7 0.2 4e-07 29.5 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 AEO58969.1 - 1.8e-05 24.4 0.0 5e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase Pex14_N PF04695.8 AEO58969.1 - 0.0028 17.6 4.1 0.014 15.4 0.2 2.3 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region PAT1 PF09770.4 AEO58969.1 - 0.03 12.5 10.6 0.036 12.3 7.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ceramidase_alk PF04734.8 AEO58970.1 - 3.5e-286 950.5 0.0 4e-286 950.3 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase Rcd1 PF04078.8 AEO58971.1 - 1.2e-130 434.0 4.4 1.5e-130 433.7 3.0 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like OSCP PF00213.13 AEO58971.1 - 0.11 12.3 1.9 0.95 9.2 0.0 2.5 2 0 0 2 2 2 0 ATP synthase delta (OSCP) subunit Na_H_Exchanger PF00999.16 AEO58972.1 - 2.4e-60 204.0 34.8 3.6e-60 203.4 24.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Pyr_redox_2 PF07992.9 AEO58973.1 - 2.7e-33 115.5 0.2 4e-32 111.7 0.2 3.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.17 AEO58973.1 - 1.9e-29 102.0 0.0 4e-29 101.0 0.0 1.6 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox PF00070.22 AEO58973.1 - 9.7e-19 67.5 4.7 2.2e-16 60.0 0.7 3.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.10 AEO58973.1 - 3.2e-12 46.2 3.5 3.2e-12 46.2 2.4 2.8 3 0 0 3 3 2 1 BFD-like [2Fe-2S] binding domain Rieske_2 PF13806.1 AEO58973.1 - 6.6e-11 41.8 0.0 6.5e-09 35.4 0.0 2.7 1 1 0 1 1 1 1 Rieske-like [2Fe-2S] domain NIR_SIR_ferr PF03460.12 AEO58973.1 - 1.6e-10 40.4 0.0 3.2e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rieske PF00355.21 AEO58973.1 - 3.2e-09 36.2 0.1 2e-08 33.6 0.0 2.4 3 0 0 3 3 3 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 AEO58973.1 - 5.5e-07 29.8 0.1 0.00044 20.3 0.0 2.8 2 1 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 AEO58973.1 - 3.7e-06 26.7 1.6 0.18 11.5 0.0 4.2 4 0 0 4 4 4 2 FAD-NAD(P)-binding HI0933_like PF03486.9 AEO58973.1 - 0.0021 16.5 0.2 3.7 5.9 0.0 3.4 3 1 1 4 4 4 2 HI0933-like protein K_oxygenase PF13434.1 AEO58973.1 - 0.0029 16.5 0.0 0.015 14.2 0.0 2.1 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 AEO58973.1 - 0.0081 16.3 0.7 0.27 11.5 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.1 AEO58973.1 - 0.0092 15.9 0.4 0.12 12.4 0.1 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.16 AEO58973.1 - 0.076 12.5 0.4 1 8.8 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 AEO58973.1 - 0.15 12.0 0.9 13 5.8 0.1 2.6 2 0 0 2 2 2 0 TrkA-N domain Lycopene_cycl PF05834.7 AEO58973.1 - 0.17 10.7 1.5 15 4.3 0.0 3.0 4 0 0 4 4 4 0 Lycopene cyclase protein O-antigen_lig PF13425.1 AEO58974.1 - 6.7 6.7 10.3 20 5.1 0.0 2.5 2 0 0 2 2 2 0 O-antigen ligase like membrane protein Pyridox_ox_2 PF12900.2 AEO58975.1 - 0.00021 21.1 0.0 0.00022 21.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.2 AEO58976.1 - 9.7e-27 93.5 0.0 1.6e-26 92.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Methyltransf_26 PF13659.1 AEO58977.1 - 2.9e-07 30.5 0.6 5.4e-06 26.4 0.1 2.4 2 0 0 2 2 2 1 Methyltransferase domain Spermine_synth PF01564.12 AEO58977.1 - 3.3e-06 26.2 0.0 5.1e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_18 PF12847.2 AEO58977.1 - 0.00045 20.7 0.0 0.00097 19.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO58977.1 - 0.001 18.8 0.0 0.01 15.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain AlaDh_PNT_C PF01262.16 AEO58977.1 - 0.12 11.9 0.0 0.28 10.7 0.0 1.6 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PEMT PF04191.8 AEO58978.1 - 9.6e-31 106.0 3.7 1.6e-30 105.3 2.3 1.6 2 0 0 2 2 2 1 Phospholipid methyltransferase Steroid_dh PF02544.11 AEO58978.1 - 0.09 12.5 0.2 0.42 10.3 0.1 2.0 2 1 0 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase Piwi PF02171.12 AEO58979.1 - 2.6e-74 249.9 0.0 4.2e-74 249.2 0.0 1.3 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 AEO58979.1 - 4.8e-09 35.4 0.0 1e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 AEO58979.1 - 7.2e-08 31.8 0.0 2.2e-07 30.2 0.0 1.8 2 0 0 2 2 2 1 PAZ domain ESSS PF10183.4 AEO58980.1 - 5.2e-26 91.0 1.1 6.5e-26 90.7 0.7 1.3 1 1 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Aminotran_4 PF01063.14 AEO58981.1 - 1.6e-30 106.3 0.0 2e-30 105.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Pkinase PF00069.20 AEO58982.1 - 2.5e-18 66.1 0.0 4.9e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO58982.1 - 7.5e-08 31.7 0.0 3.4e-07 29.6 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.1 AEO58982.1 - 0.042 14.1 0.1 18 5.6 0.0 3.4 3 0 0 3 3 3 0 HEAT repeats SIR2 PF02146.12 AEO58983.1 - 2.4e-59 200.0 0.0 3.4e-59 199.5 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 AEO58983.1 - 2.4e-05 23.9 0.0 4.4e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 AEO58983.1 - 0.025 14.3 0.1 2.7 7.7 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain E1-E2_ATPase PF00122.15 AEO58984.1 - 3.5e-58 196.3 1.9 3.5e-58 196.3 1.3 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 AEO58984.1 - 4.5e-44 150.1 7.9 4.5e-44 150.1 5.5 3.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 AEO58984.1 - 2.3e-30 106.6 0.0 1.4e-29 104.0 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AEO58984.1 - 2.9e-19 68.7 0.0 6.7e-19 67.6 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 AEO58984.1 - 1.7e-17 64.2 0.0 3.2e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 AEO58984.1 - 1.1e-06 28.4 0.4 5.8e-06 26.0 0.4 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 AEO58984.1 - 0.00013 21.3 0.1 0.00013 21.3 0.0 3.6 4 0 0 4 4 4 1 Cation transporter/ATPase, N-terminus Cortexin PF11057.3 AEO58984.1 - 0.0058 16.2 0.1 1.3 8.7 0.0 2.8 2 0 0 2 2 2 1 Cortexin of kidney DUF2976 PF11190.3 AEO58984.1 - 0.099 12.1 14.1 0.025 14.0 0.6 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF2976) TTL PF03133.10 AEO58985.1 - 7.6e-54 182.6 0.0 6.9e-35 120.3 0.0 2.6 3 0 0 3 3 3 2 Tubulin-tyrosine ligase family SurE PF01975.12 AEO58985.1 - 1.1e-40 139.0 0.0 2.3e-39 134.7 0.0 2.6 2 1 0 2 2 2 1 Survival protein SurE ATPgrasp_YheCD PF14398.1 AEO58985.1 - 0.00059 18.7 0.0 0.015 14.1 0.0 2.3 2 0 0 2 2 2 1 YheC/D like ATP-grasp ATP-grasp_4 PF13535.1 AEO58985.1 - 0.0095 15.6 0.0 0.06 13.0 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain DASH_Duo1 PF08651.5 AEO58987.1 - 8.3e-33 111.8 0.7 1.2e-32 111.2 0.5 1.3 1 0 0 1 1 1 1 DASH complex subunit Duo1 DUF3340 PF11818.3 AEO58987.1 - 0.0018 18.2 1.1 0.0018 18.2 0.8 1.6 2 0 0 2 2 2 1 C-terminal domain of tail specific protease (DUF3340) DUF745 PF05335.8 AEO58987.1 - 0.017 14.6 7.8 0.029 13.8 5.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) BRF1 PF07741.8 AEO58987.1 - 0.26 11.5 11.3 0.32 11.2 4.2 2.2 2 0 0 2 2 2 0 Brf1-like TBP-binding domain ARGLU PF15346.1 AEO58987.1 - 0.43 10.3 18.1 0.061 13.0 9.1 1.9 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 Sporozoite_P67 PF05642.6 AEO58987.1 - 0.79 7.5 6.7 1.3 6.8 4.7 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Syntaxin-6_N PF09177.6 AEO58987.1 - 0.88 10.0 8.5 0.55 10.6 4.6 1.6 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF2514 PF10721.4 AEO58987.1 - 4.8 6.8 16.4 0.26 10.9 5.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) RNase_H2-Ydr279 PF09468.5 AEO58988.1 - 1e-84 284.3 0.0 1.3e-84 283.9 0.0 1.1 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) RAP1 PF07218.6 AEO58988.1 - 4.3 5.3 8.9 5.6 4.9 6.2 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) zf-primase PF09329.6 AEO58989.1 - 4.1e-17 61.5 3.6 6.6e-17 60.8 2.5 1.3 1 0 0 1 1 1 1 Primase zinc finger tRNA_anti-codon PF01336.20 AEO58989.1 - 0.0058 16.4 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Dna2 PF08696.6 AEO58990.1 - 1.7e-72 243.0 0.0 6.2e-72 241.2 0.0 1.8 2 0 0 2 2 2 1 DNA replication factor Dna2 AAA_12 PF13087.1 AEO58990.1 - 2.4e-37 128.2 0.0 4.1e-37 127.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Cas_Cas4 PF01930.12 AEO58990.1 - 6.1e-10 39.2 0.2 2.3e-08 34.1 0.1 2.6 3 0 0 3 3 3 1 Domain of unknown function DUF83 PDDEXK_1 PF12705.2 AEO58990.1 - 2e-08 33.9 0.0 3.9e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily DUF911 PF06023.7 AEO58990.1 - 0.016 14.4 0.2 0.063 12.4 0.1 1.9 1 1 0 1 1 1 0 Archaeal protein of unknown function (DUF911) Gryzun PF07919.7 AEO58991.1 - 2.3e-104 349.7 0.0 3e-104 349.3 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 AEO58991.1 - 8e-82 274.4 0.6 6.4e-79 264.9 0.8 2.2 2 0 0 2 2 2 2 Foie gras liver health family 1 Gryzun-like PF12742.2 AEO58991.1 - 0.0016 18.2 0.0 0.0029 17.3 0.0 1.3 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking DUF3210 PF11489.3 AEO58992.1 - 7.5e-230 765.3 81.6 7.5e-230 765.3 56.6 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3210) Cg6151-P PF10233.4 AEO58993.1 - 1.4e-28 99.1 1.0 1.7e-28 98.8 0.7 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P Cytochrom_B558a PF05038.8 AEO58993.1 - 0.2 11.2 1.5 0.28 10.8 1.0 1.4 1 1 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit MFS_1 PF07690.11 AEO58994.1 - 1.3e-18 66.8 38.7 1.3e-18 66.8 26.8 2.8 1 1 2 3 3 3 2 Major Facilitator Superfamily ATG22 PF11700.3 AEO58994.1 - 4.3e-07 28.7 10.2 4.3e-07 28.7 7.1 1.5 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_2 PF13347.1 AEO58994.1 - 0.085 11.2 28.0 0.44 8.8 8.1 2.4 2 1 0 2 2 2 0 MFS/sugar transport protein NTF2 PF02136.15 AEO58995.1 - 4.8e-31 107.5 0.0 5.5e-31 107.3 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain OKR_DC_1_C PF03711.10 AEO58995.1 - 0.025 14.6 0.0 0.029 14.4 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, C-terminal domain Seipin PF06775.9 AEO58997.1 - 3.1e-22 79.0 0.0 4e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) FCH PF00611.18 AEO58998.1 - 5.8e-22 77.6 0.1 5.8e-22 77.6 0.0 2.4 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 AEO58998.1 - 4.6e-14 51.5 0.0 8.6e-14 50.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 AEO58998.1 - 5.5e-12 44.9 0.0 2.8e-11 42.7 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 AEO58998.1 - 1.2e-10 40.8 0.0 2.5e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain UPF0029 PF01205.14 AEO58999.1 - 6.4e-24 83.7 0.5 2e-23 82.1 0.0 2.1 3 0 0 3 3 3 1 Uncharacterized protein family UPF0029 Cnd1_N PF12922.2 AEO58999.1 - 0.19 11.3 1.3 16 5.0 0.3 2.4 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term Ribosomal_60s PF00428.14 AEO58999.1 - 7.2 7.0 9.4 18 5.8 3.2 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein Methyltransf_23 PF13489.1 AEO59000.1 - 1.1e-12 47.9 0.0 2.7e-12 46.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO59000.1 - 0.00027 21.3 0.0 2.1 8.8 0.0 3.0 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_12 PF08242.7 AEO59000.1 - 0.00085 19.7 0.0 0.011 16.2 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO59000.1 - 0.026 15.1 0.0 0.18 12.3 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.1 AEO59000.1 - 0.032 13.8 0.0 6 6.4 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Not1 PF04054.10 AEO59002.1 - 7.1e-112 374.0 0.0 1.5e-111 372.9 0.0 1.6 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 AEO59002.1 - 5.5e-49 165.6 1.3 5.5e-49 165.6 0.9 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) CorA PF01544.13 AEO59003.1 - 5.4e-12 45.3 6.2 1.6e-11 43.8 4.3 1.8 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF676 PF05057.9 AEO59003.1 - 4.9e-05 22.7 0.1 0.00013 21.3 0.0 1.7 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 AEO59003.1 - 0.00023 21.1 0.0 0.0014 18.5 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 AEO59003.1 - 0.034 13.7 0.0 0.078 12.5 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein MASE1 PF05231.9 AEO59003.1 - 0.04 12.9 1.0 0.069 12.1 0.7 1.3 1 0 0 1 1 1 0 MASE1 DUF2232 PF09991.4 AEO59003.1 - 0.44 9.5 4.7 0.18 10.7 0.5 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) ETF_QO PF05187.8 AEO59004.1 - 1.8e-45 153.4 0.0 3e-45 152.7 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 AEO59004.1 - 1e-07 31.1 0.1 0.00022 20.2 0.0 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AEO59004.1 - 1.5e-07 31.3 0.0 4.3e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 AEO59004.1 - 3.8e-05 22.9 0.0 6.6e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 AEO59004.1 - 0.00013 20.9 0.4 0.0031 16.4 0.5 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 AEO59004.1 - 0.00014 21.7 0.0 0.00024 21.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 AEO59004.1 - 0.00022 19.8 0.3 0.00032 19.2 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 AEO59004.1 - 0.00028 20.0 0.0 0.0034 16.4 0.0 2.1 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.1 AEO59004.1 - 0.00097 18.9 0.3 0.0053 16.5 0.1 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 AEO59004.1 - 0.001 18.1 0.2 0.0019 17.3 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 AEO59004.1 - 0.0015 17.2 0.0 0.2 10.2 0.0 2.2 1 1 1 2 2 2 2 Tryptophan halogenase Fer4_7 PF12838.2 AEO59004.1 - 0.0026 18.1 1.1 0.0074 16.6 0.8 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain Pyr_redox_3 PF13738.1 AEO59004.1 - 0.003 17.6 0.0 0.0058 16.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 AEO59004.1 - 0.015 14.2 0.2 0.024 13.5 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.22 AEO59004.1 - 0.026 14.9 0.1 4.8 7.6 0.1 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 AEO59004.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A EmrE PF13536.1 AEO59005.1 - 0.035 14.3 0.1 0.035 14.3 0.1 1.0 1 0 0 1 1 1 0 Multidrug resistance efflux transporter DoxX_2 PF13564.1 AEO59005.1 - 0.084 12.8 0.1 0.084 12.8 0.0 1.1 1 0 0 1 1 1 0 DoxX-like family FA PF08736.6 AEO59005.1 - 0.13 12.0 0.3 0.15 11.8 0.2 1.1 1 0 0 1 1 1 0 FERM adjacent (FA) TBP PF00352.16 AEO59006.1 - 2.3e-70 231.9 0.2 3.4e-35 119.2 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 AEO59006.1 - 0.00021 21.3 0.0 0.77 9.8 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Pollen_allerg_2 PF01620.11 AEO59006.1 - 0.024 14.9 0.5 0.034 14.4 0.4 1.3 1 0 0 1 1 1 0 Ribonuclease (pollen allergen) DAO PF01266.19 AEO59007.1 - 3.1e-53 180.9 0.4 4e-53 180.5 0.3 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 AEO59007.1 - 1.2e-10 41.3 0.2 0.0002 21.1 0.0 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 AEO59007.1 - 0.00017 21.5 0.0 0.47 10.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AEO59007.1 - 0.00061 19.7 0.1 0.004 17.1 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 AEO59007.1 - 0.0011 17.8 0.1 0.0032 16.3 0.0 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 AEO59007.1 - 0.0074 14.9 0.1 0.57 8.7 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_3 PF13738.1 AEO59007.1 - 0.037 14.0 0.0 0.3 11.1 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 AEO59007.1 - 0.06 12.2 0.1 8.8 5.1 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.22 AEO59007.1 - 0.063 13.6 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Saccharop_dh PF03435.13 AEO59007.1 - 0.078 11.9 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase FAD_binding_2 PF00890.19 AEO59007.1 - 0.1 11.4 4.3 2.7 6.7 3.0 2.2 1 1 0 1 1 1 0 FAD binding domain Surp PF01805.15 AEO59008.1 - 2.3e-17 62.3 0.0 4.4e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 Surp module Copper-fist PF00649.13 AEO59009.1 - 2.6e-18 64.9 0.9 5.1e-18 63.9 0.7 1.5 1 0 0 1 1 1 1 Copper fist DNA binding domain DUF605 PF04652.11 AEO59010.1 - 0.17 11.2 16.0 0.22 10.8 11.1 1.1 1 0 0 1 1 1 0 Vta1 like TFIIA PF03153.8 AEO59010.1 - 0.23 11.3 1.5 0.29 10.9 1.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SpoIIIAH PF12685.2 AEO59010.1 - 0.47 9.9 2.5 1.2 8.5 1.7 1.8 1 1 0 1 1 1 0 SpoIIIAH-like protein Methyltransf_16 PF10294.4 AEO59011.1 - 3.4e-06 26.6 0.0 3.6e-05 23.2 0.0 2.2 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 AEO59011.1 - 0.00018 22.0 0.0 0.00028 21.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 AEO59011.1 - 0.0066 15.6 0.5 0.0095 15.0 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) COX15-CtaA PF02628.10 AEO59013.1 - 0.046 12.5 2.3 0.074 11.9 1.6 1.3 1 0 0 1 1 1 0 Cytochrome oxidase assembly protein Orai-1 PF07856.7 AEO59013.1 - 0.086 12.3 0.1 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 Mediator of CRAC channel activity SNF2_N PF00176.18 AEO59014.1 - 1.8e-77 260.0 0.1 1.2e-70 237.7 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 AEO59014.1 - 4.1e-09 36.1 0.0 1.1e-08 34.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_34 PF13872.1 AEO59014.1 - 2.3e-05 23.3 0.0 6.5e-05 21.8 0.0 1.7 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 ResIII PF04851.10 AEO59014.1 - 0.00011 22.0 0.0 0.00051 19.9 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 AEO59014.1 - 0.0044 15.8 0.0 5.1 5.8 0.0 3.2 4 0 0 4 4 4 2 Class II histone deacetylase complex subunits 2 and 3 DEAD_2 PF06733.10 AEO59014.1 - 0.023 14.1 0.3 0.059 12.7 0.0 1.8 2 0 0 2 2 2 0 DEAD_2 MFS_1 PF07690.11 AEO59015.1 - 2.8e-31 108.5 40.2 3.2e-31 108.3 27.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1049 PF06305.6 AEO59015.1 - 0.35 10.3 6.9 17 4.9 0.0 4.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) Ran-binding PF05508.6 AEO59016.1 - 2.9e-105 351.5 0.0 3.6e-105 351.1 0.0 1.1 1 0 0 1 1 1 1 RanGTP-binding protein Nop14 PF04147.7 AEO59016.1 - 1.5 6.6 10.4 2.2 6.0 7.2 1.1 1 0 0 1 1 1 0 Nop14-like family GTP_EFTU PF00009.22 AEO59017.1 - 3.5e-43 147.2 0.0 6.2e-43 146.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 AEO59017.1 - 2.8e-20 72.3 0.4 8e-20 70.8 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 AEO59017.1 - 1.3e-06 28.4 0.2 3.4e-06 27.0 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 AEO59017.1 - 8.6e-05 22.4 0.0 0.00029 20.7 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 AEO59017.1 - 0.088 13.3 0.0 0.6 10.6 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein G-alpha PF00503.15 AEO59017.1 - 1.1 7.8 6.8 4.3 5.9 4.7 1.9 1 1 0 1 1 1 0 G-protein alpha subunit Mitofilin PF09731.4 AEO59017.1 - 1.8 7.1 16.4 2.6 6.5 11.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein adh_short PF00106.20 AEO59018.1 - 1.2e-20 74.1 6.2 1.1e-19 70.9 4.3 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO59018.1 - 2.2e-16 60.3 0.2 1.1e-15 58.0 0.1 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO59018.1 - 1.9e-08 34.1 0.8 1.9e-08 34.1 0.6 1.9 2 1 0 2 2 2 1 KR domain Shikimate_DH PF01488.15 AEO59018.1 - 0.018 15.1 0.2 0.03 14.4 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 AEO59018.1 - 0.13 11.0 0.2 0.33 9.8 0.0 1.7 3 0 0 3 3 3 0 Polysaccharide biosynthesis protein Mito_carr PF00153.22 AEO59019.1 - 6.8e-55 182.7 3.9 1.1e-19 69.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein UCH_1 PF13423.1 AEO59020.1 - 3.6e-58 197.3 0.0 5.2e-58 196.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 AEO59020.1 - 2.7e-26 92.7 0.0 4.6e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 Exonuclease UCH PF00443.24 AEO59020.1 - 3.3e-07 29.7 0.0 2e-06 27.1 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Nup96 PF12110.3 AEO59021.1 - 6.4e-52 176.4 0.0 9.3e-52 175.9 0.0 1.3 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 AEO59022.1 - 5.4e-44 149.4 0.0 7.8e-44 148.9 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 AEO59022.1 - 2e-15 57.0 366.2 3.4e-06 27.2 45.3 10.0 3 3 5 8 8 8 3 Nucleoporin FG repeat region ENTH PF01417.15 AEO59023.1 - 3.8e-50 168.9 0.0 7.2e-50 168.0 0.0 1.5 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 AEO59023.1 - 0.0017 17.1 0.0 0.0033 16.1 0.0 1.4 1 0 0 1 1 1 1 ANTH domain DUF4264 PF14084.1 AEO59023.1 - 0.0035 16.6 0.0 0.0062 15.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4264) DUF1720 PF08226.6 AEO59023.1 - 0.0067 16.4 42.5 0.0067 16.4 29.5 5.7 2 1 2 4 4 4 1 Domain of unknown function (DUF1720) UIM PF02809.15 AEO59023.1 - 0.025 14.1 1.2 0.025 14.1 0.8 2.8 2 0 0 2 2 2 0 Ubiquitin interaction motif DUF1510 PF07423.6 AEO59023.1 - 1.4 8.2 20.5 0.67 9.2 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1510) MOZ_SAS PF01853.13 AEO59024.1 - 9.3e-80 266.3 0.1 1.3e-79 265.7 0.1 1.2 1 0 0 1 1 1 1 MOZ/SAS family ATP_bind_3 PF01171.15 AEO59025.1 - 2.4e-18 66.2 0.0 4e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 PP-loop family DUF2392 PF10288.4 AEO59025.1 - 0.00055 20.2 0.0 0.001 19.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) tRNA_Me_trans PF03054.11 AEO59025.1 - 0.0054 15.3 0.0 0.0084 14.6 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase RecR PF02132.10 AEO59025.1 - 0.0057 16.0 0.9 0.0057 16.0 0.6 3.2 4 0 0 4 4 4 1 RecR protein ThiI PF02568.9 AEO59025.1 - 0.11 11.9 0.0 0.29 10.5 0.0 1.7 1 1 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) zf-UBR PF02207.15 AEO59025.1 - 0.46 10.2 5.8 4 7.2 0.3 2.7 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) DZR PF12773.2 AEO59025.1 - 4.2 7.2 10.2 5.4 6.9 0.3 3.3 3 0 0 3 3 3 0 Double zinc ribbon GATA PF00320.22 AEO59025.1 - 7.9 5.9 13.0 0.14 11.4 0.4 3.4 3 1 0 3 3 3 0 GATA zinc finger Ribosomal_L7Ae PF01248.21 AEO59026.1 - 4.3e-21 74.2 0.8 7.6e-21 73.4 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family CLPTM1 PF05602.7 AEO59026.1 - 0.049 12.3 0.2 0.059 12.0 0.1 1.1 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) Pro_CA PF00484.14 AEO59027.1 - 6.3e-46 156.1 0.1 7.5e-46 155.8 0.1 1.1 1 0 0 1 1 1 1 Carbonic anhydrase OCD_Mu_crystall PF02423.10 AEO59028.1 - 3.2e-07 29.4 1.1 0.0092 14.7 0.3 3.0 2 2 0 2 2 2 2 Ornithine cyclodeaminase/mu-crystallin family peroxidase PF00141.18 AEO59029.1 - 1.2e-24 87.1 0.1 1.8e-24 86.4 0.1 1.3 1 0 0 1 1 1 1 Peroxidase DUF3415 PF11895.3 AEO59029.1 - 0.016 15.0 0.0 0.095 12.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3415) Spp-24 PF07448.6 AEO59030.1 - 0.033 14.1 0.1 0.042 13.8 0.1 1.1 1 0 0 1 1 1 0 Secreted phosphoprotein 24 (Spp-24) MASE1 PF05231.9 AEO59030.1 - 0.073 12.0 4.7 0.087 11.8 3.2 1.1 1 0 0 1 1 1 0 MASE1 AATF-Che1 PF13339.1 AEO59031.1 - 3.4e-33 114.5 2.3 3.4e-33 114.5 1.6 3.5 3 1 0 3 3 3 1 Apoptosis antagonizing transcription factor TRAUB PF08164.7 AEO59031.1 - 6.5e-32 109.4 0.3 3.8e-31 107.0 0.0 2.6 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal Nop14 PF04147.7 AEO59031.1 - 0.34 8.7 78.8 0.026 12.4 24.6 2.5 2 0 0 2 2 2 0 Nop14-like family ParA PF10609.4 AEO59032.1 - 6e-33 112.5 0.6 2.6e-32 110.5 0.2 2.0 1 1 1 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 AEO59032.1 - 9.5e-15 54.5 0.3 1.6e-14 53.7 0.1 1.4 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 AEO59032.1 - 5.9e-07 29.5 0.1 3.3e-06 27.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain Fer4_NifH PF00142.13 AEO59032.1 - 5e-05 22.6 0.0 0.049 12.8 0.0 2.2 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MipZ PF09140.6 AEO59032.1 - 6.9e-05 22.0 0.8 0.0001 21.4 0.0 1.6 2 0 0 2 2 2 1 ATPase MipZ AAA_26 PF13500.1 AEO59032.1 - 0.00035 20.2 0.5 0.02 14.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 AEO59032.1 - 0.0042 16.1 0.3 0.01 14.9 0.0 1.7 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.1 AEO59032.1 - 0.017 14.5 0.5 0.03 13.7 0.1 1.6 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 AEO59032.1 - 0.044 12.5 0.2 0.044 12.5 0.2 1.9 2 0 0 2 2 2 0 ArgK protein UPF0126 PF03458.8 AEO59032.1 - 0.045 13.3 0.4 0.11 12.0 0.3 1.6 1 0 0 1 1 1 0 UPF0126 domain YhjQ PF06564.7 AEO59032.1 - 0.099 11.9 1.7 0.11 11.8 0.5 1.5 2 0 0 2 2 2 0 YhjQ protein DUF4537 PF15057.1 AEO59033.1 - 0.0059 16.3 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) Fis1_TPR_C PF14853.1 AEO59033.1 - 0.1 12.4 0.5 0.22 11.4 0.4 1.5 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TCO89 PF10452.4 AEO59034.1 - 1.3 7.7 19.5 0.19 10.6 0.1 3.4 3 1 0 3 3 3 0 TORC1 subunit TCO89 Thiolase_N PF00108.18 AEO59035.1 - 1.7e-77 259.9 2.7 2.6e-77 259.3 1.9 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 AEO59035.1 - 7.9e-45 151.2 0.1 1.9e-44 150.0 0.0 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 AEO59035.1 - 0.013 14.9 1.7 0.028 13.8 0.3 2.2 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.5 AEO59035.1 - 0.016 15.2 0.0 0.05 13.6 0.0 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal FBPase PF00316.15 AEO59036.1 - 3.1e-124 414.0 0.0 3.6e-124 413.8 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Inositol_P PF00459.20 AEO59036.1 - 0.075 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Inositol monophosphatase family F-box-like PF12937.2 AEO59037.1 - 5.2e-05 22.8 0.8 5.2e-05 22.8 0.6 2.3 2 0 0 2 2 2 1 F-box-like WD40 PF00400.27 AEO59037.1 - 0.024 14.5 0.0 22 5.1 0.0 3.5 3 0 0 3 3 3 0 WD domain, G-beta repeat F-box PF00646.28 AEO59037.1 - 0.069 12.8 1.7 0.27 10.9 1.1 2.1 1 0 0 1 1 1 0 F-box domain p450 PF00067.17 AEO59038.1 - 6e-41 140.4 0.0 7.6e-39 133.5 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Sugar_tr PF00083.19 AEO59039.1 - 1.6e-31 109.3 37.8 3.3e-19 68.8 9.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 AEO59039.1 - 2.3e-20 72.6 48.5 4.6e-12 45.3 17.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Chal_sti_synt_N PF00195.14 AEO59040.1 - 1.5e-18 66.9 0.0 2.2e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Chal_sti_synt_C PF02797.10 AEO59040.1 - 1.5e-16 60.7 0.0 7.6e-16 58.3 0.0 2.0 2 0 0 2 2 2 1 Chalcone and stilbene synthases, C-terminal domain FAE1_CUT1_RppA PF08392.7 AEO59040.1 - 1.7e-06 27.3 0.0 2.4e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.5 AEO59040.1 - 0.00024 21.0 0.3 0.038 14.0 0.0 2.8 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.5 AEO59040.1 - 0.0003 20.3 0.1 0.00078 19.0 0.0 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III PEX11 PF05648.9 AEO59041.1 - 4e-74 248.6 0.4 4.4e-74 248.5 0.3 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) NMO PF03060.10 AEO59042.1 - 1.7e-64 218.0 0.1 2.3e-64 217.6 0.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 AEO59042.1 - 7e-11 41.6 0.0 1.2e-05 24.4 0.0 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 AEO59042.1 - 0.015 14.1 0.2 0.027 13.3 0.2 1.5 1 0 0 1 1 1 0 FMN-dependent dehydrogenase DUF1902 PF08972.6 AEO59042.1 - 0.05 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) NanE PF04131.9 AEO59042.1 - 0.21 10.5 0.0 0.21 10.5 0.0 1.7 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase APH PF01636.18 AEO59043.1 - 0.03 14.0 0.0 0.063 13.0 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family DND1_DSRM PF14709.1 AEO59044.1 - 0.00023 21.3 0.0 0.0005 20.2 0.0 1.6 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.20 AEO59044.1 - 0.071 13.6 0.0 0.12 13.0 0.0 1.4 1 0 0 1 1 1 0 Double-stranded RNA binding motif Ribosomal_S7 PF00177.16 AEO59045.1 - 3.6e-26 91.5 0.0 5.1e-26 91.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Usp PF00582.21 AEO59046.1 - 1.4e-21 77.1 6.0 7.6e-21 74.7 0.9 2.9 2 1 0 2 2 2 1 Universal stress protein family RRM_1 PF00076.17 AEO59048.1 - 5.2e-86 282.3 4.5 1.3e-23 82.4 0.3 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO59048.1 - 4.8e-56 186.6 0.5 2e-16 59.6 0.0 5.6 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO59048.1 - 3.5e-42 142.0 0.1 1.4e-11 44.0 0.0 5.5 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 AEO59048.1 - 2e-30 104.2 2.1 1e-29 101.9 1.5 2.2 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.1 AEO59048.1 - 1.1e-05 25.1 0.7 11 5.9 0.0 5.0 4 1 0 4 4 4 2 Nup53/35/40-type RNA recognition motif CbiG_mid PF11761.3 AEO59048.1 - 0.00014 22.0 0.1 5 7.4 0.0 3.8 3 0 0 3 3 3 2 Cobalamin biosynthesis central region Limkain-b1 PF11608.3 AEO59048.1 - 0.0051 16.5 2.0 7.8 6.3 0.1 3.5 3 0 0 3 3 3 1 Limkain b1 OB_RNB PF08206.6 AEO59048.1 - 0.051 13.0 2.1 7.8 6.0 0.0 3.6 3 0 0 3 3 3 0 Ribonuclease B OB domain HECT PF00632.20 AEO59049.1 - 5.5e-86 288.5 0.0 7.8e-86 288.0 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 AEO59049.1 - 0.005 16.3 4.8 0.016 14.7 3.4 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif DUF1501 PF07394.7 AEO59049.1 - 0.1 11.4 4.0 0.17 10.6 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Glyco_hydro_92 PF07971.7 AEO59050.1 - 1.2e-174 581.6 0.0 1.5e-174 581.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Zn_clus PF00172.13 AEO59051.1 - 2.1e-08 33.9 7.3 2.1e-08 33.9 5.1 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 AEO59051.1 - 0.16 10.5 0.0 0.21 10.1 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain RTA1 PF04479.8 AEO59052.1 - 1.3e-21 77.0 2.7 4.7e-20 72.0 0.2 2.0 2 0 0 2 2 2 2 RTA1 like protein MarR_2 PF12802.2 AEO59052.1 - 0.12 12.0 0.8 0.55 9.9 0.0 2.3 3 0 0 3 3 3 0 MarR family PepSY_TM_2 PF13703.1 AEO59052.1 - 8 6.7 8.3 7.7 6.7 0.1 3.0 2 1 1 3 3 3 0 PepSY-associated TM helix PTPA PF03095.10 AEO59053.1 - 4.6e-99 331.3 0.0 5.3e-99 331.1 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein SET PF00856.23 AEO59054.1 - 2.6e-06 27.8 0.0 0.08 13.2 0.0 3.0 2 1 0 2 2 2 2 SET domain Rad4 PF03835.10 AEO59055.1 - 6.3e-28 97.0 0.0 1.7e-27 95.6 0.0 1.7 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 AEO59055.1 - 1.6e-26 91.8 0.0 2.9e-26 90.9 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 AEO59055.1 - 6.5e-20 70.4 0.0 1.3e-19 69.4 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 AEO59055.1 - 9.7e-12 45.0 0.0 3.6e-11 43.2 0.0 2.1 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 AEO59055.1 - 0.00054 20.1 0.5 0.0019 18.4 0.3 2.0 1 1 0 1 1 1 1 Transglutaminase-like superfamily Ribosomal_60s PF00428.14 AEO59055.1 - 0.0055 17.0 0.5 0.0055 17.0 0.3 3.2 3 0 0 3 3 3 1 60s Acidic ribosomal protein Orthopox_C10L PF07020.6 AEO59056.1 - 0.86 10.1 11.4 1.4 9.4 6.1 2.3 2 0 0 2 2 2 0 Orthopoxvirus C10L protein COX15-CtaA PF02628.10 AEO59057.1 - 1.9e-96 322.4 9.5 2.4e-96 322.1 6.6 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein DUF3285 PF11688.3 AEO59057.1 - 0.0012 18.4 0.1 0.0052 16.3 0.0 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3285) RuvC PF02075.12 AEO59057.1 - 0.026 14.3 0.3 0.05 13.4 0.2 1.4 1 0 0 1 1 1 0 Crossover junction endodeoxyribonuclease RuvC CcoS PF03597.10 AEO59057.1 - 1.4 8.4 3.6 22 4.6 0.4 3.1 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type Zip PF02535.17 AEO59058.1 - 1e-44 152.8 3.3 5e-44 150.5 2.3 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter Pkinase PF00069.20 AEO59059.1 - 1.8e-06 27.3 0.0 7.8e-06 25.2 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO59059.1 - 0.015 14.3 0.0 0.048 12.7 0.0 1.8 1 1 0 1 1 1 0 Protein tyrosine kinase Robl_LC7 PF03259.12 AEO59060.1 - 0.067 12.7 0.1 0.067 12.7 0.1 2.3 3 0 0 3 3 3 0 Roadblock/LC7 domain Hpr_kinase_N PF02603.11 AEO59062.1 - 0.046 13.4 0.7 1.3 8.6 0.2 2.2 2 1 0 2 2 2 0 HPr Serine kinase N terminus RVT_1 PF00078.22 AEO59062.1 - 0.068 12.5 0.1 0.07 12.4 0.1 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Recep_L_domain PF01030.19 AEO59062.1 - 0.071 13.0 0.8 0.54 10.2 0.6 1.9 1 1 0 1 1 1 0 Receptor L domain Nop52 PF05997.7 AEO59062.1 - 0.11 11.9 0.2 0.11 11.9 0.1 1.2 1 1 0 1 1 1 0 Nucleolar protein,Nop52 2-Hacid_dh_C PF02826.14 AEO59063.1 - 6.5e-51 171.9 0.0 1e-50 171.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 AEO59063.1 - 6.5e-34 116.2 0.1 1.2e-33 115.4 0.0 1.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.1 AEO59063.1 - 0.011 16.0 0.0 0.024 14.9 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain NAD_binding_2 PF03446.10 AEO59063.1 - 0.028 14.2 0.4 0.081 12.7 0.0 1.9 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.16 AEO59063.1 - 0.036 13.6 0.8 0.08 12.5 0.5 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ACT PF01842.20 AEO59063.1 - 0.13 11.7 2.3 0.2 11.2 0.0 2.5 3 0 0 3 3 3 0 ACT domain Glyoxalase PF00903.20 AEO59064.1 - 2.8e-33 114.6 0.0 4.9e-20 71.7 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 AEO59064.1 - 4.6e-28 97.9 0.1 1.3e-16 61.0 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 AEO59064.1 - 1.8e-15 56.8 0.0 7.5e-09 35.5 0.0 2.9 2 2 1 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 AEO59064.1 - 5.8e-05 23.0 0.0 0.46 10.3 0.0 2.7 1 1 1 2 2 2 2 Glyoxalase-like domain DUF21 PF01595.15 AEO59065.1 - 5.6e-31 107.2 0.0 8.9e-31 106.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 AEO59065.1 - 8.1e-05 22.3 0.5 0.0071 16.1 0.0 2.7 2 0 0 2 2 2 2 CBS domain TMF_DNA_bd PF12329.3 AEO59067.1 - 0.00041 20.0 9.1 0.00041 20.0 6.3 16.7 5 4 10 17 17 17 8 TATA element modulatory factor 1 DNA binding Filament PF00038.16 AEO59067.1 - 0.0011 18.5 171.1 0.018 14.5 28.2 6.7 1 1 4 6 6 6 4 Intermediate filament protein Phage_GP20 PF06810.6 AEO59067.1 - 0.0019 17.6 1.2 0.0019 17.6 0.8 11.9 2 1 9 11 11 11 2 Phage minor structural protein GP20 SlyX PF04102.7 AEO59067.1 - 0.04 14.3 0.6 0.04 14.3 0.4 13.4 8 3 4 15 15 15 0 SlyX Zn_clus PF00172.13 AEO59068.1 - 2.5e-10 40.0 13.1 3.7e-10 39.5 9.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 AEO59068.1 - 1.9e-05 23.6 0.0 3.6e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Med15 PF09606.5 AEO59068.1 - 0.0019 16.5 42.9 0.0019 16.5 29.7 2.3 2 0 0 2 2 2 1 ARC105 or Med15 subunit of Mediator complex non-fungal Baculo_PP31 PF05311.6 AEO59068.1 - 5 6.3 14.1 11 5.2 9.8 1.5 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Copper-fist PF00649.13 AEO59069.1 - 2.6e-22 77.7 2.6 2.6e-22 77.7 1.8 3.7 2 2 1 3 3 3 2 Copper fist DNA binding domain ApbA PF02558.11 AEO59070.1 - 1.3e-32 112.3 0.0 1.9e-32 111.8 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 AEO59070.1 - 1.2e-26 93.1 0.0 2.1e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Pyr_redox PF00070.22 AEO59070.1 - 0.066 13.6 0.0 0.17 12.3 0.0 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Mito_fiss_reg PF05308.6 AEO59070.1 - 0.93 8.8 9.0 1.3 8.2 6.2 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 AEO59070.1 - 2.3 7.4 9.5 3.4 6.8 6.6 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF1744 PF08490.7 AEO59071.1 - 9.1e-10 37.6 0.4 1.2e-09 37.2 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DUF2461 PF09365.5 AEO59075.1 - 1.4e-65 220.7 0.5 9e-65 218.0 0.3 2.0 1 1 0 1 1 1 1 Conserved hypothetical protein (DUF2461) PhyH PF05721.8 AEO59076.1 - 9.1e-10 38.9 0.1 5.4e-09 36.4 0.1 2.0 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Pectate_lyase_3 PF12708.2 AEO59077.1 - 4.3e-84 282.1 22.3 6e-69 232.5 4.4 3.1 2 1 1 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 AEO59077.1 - 1.7e-06 27.4 1.5 0.015 14.7 0.1 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Fungal_trans PF04082.13 AEO59078.1 - 1.9e-15 56.4 1.0 1.9e-15 56.4 0.7 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 AEO59078.1 - 1.8e-08 34.1 8.8 0.0012 19.0 2.6 3.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 AEO59078.1 - 4.2e-08 33.0 7.9 0.0027 17.9 2.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 AEO59078.1 - 1.2e-05 25.3 13.0 0.00023 21.2 1.4 3.2 3 0 0 3 3 3 2 Zinc-finger double domain Phostensin_N PF13916.1 AEO59078.1 - 0.024 14.6 5.0 0.037 14.0 2.0 2.3 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal zf-C2H2_jaz PF12171.3 AEO59078.1 - 0.055 13.6 0.9 0.78 9.9 0.6 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 AEO59078.1 - 0.098 12.5 0.3 20 5.2 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger PyrI_C PF02748.10 AEO59078.1 - 0.23 10.9 0.3 0.41 10.1 0.2 1.4 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain VHS PF00790.14 AEO59079.1 - 7.9e-38 129.2 0.1 1.7e-37 128.2 0.1 1.6 1 0 0 1 1 1 1 VHS domain SH3_9 PF14604.1 AEO59079.1 - 3.3e-17 61.8 0.2 6.1e-17 60.9 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 AEO59079.1 - 6.3e-17 60.6 0.1 1.5e-16 59.5 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 AEO59079.1 - 9.1e-15 53.8 0.2 2.2e-14 52.6 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain UIM PF02809.15 AEO59079.1 - 0.046 13.2 5.6 0.14 11.8 3.9 1.9 1 0 0 1 1 1 0 Ubiquitin interaction motif Arm_2 PF04826.8 AEO59079.1 - 0.057 12.5 0.2 0.11 11.5 0.1 1.5 2 0 0 2 2 2 0 Armadillo-like Mito_carr PF00153.22 AEO59080.1 - 2.9e-68 225.6 3.2 1e-24 86.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RCC1 PF00415.13 AEO59081.1 - 1.2e-24 86.2 0.0 1.9e-07 31.1 0.0 5.0 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 AEO59081.1 - 5.6e-13 48.8 0.0 1.2e-08 34.9 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.1 AEO59081.1 - 2.5e-09 37.4 0.2 9.5e-09 35.5 0.1 2.1 1 1 1 2 2 2 1 Ankyrin repeats (many copies) RCC1_2 PF13540.1 AEO59081.1 - 1.4e-07 30.8 8.5 2.2e-07 30.3 1.0 3.6 3 0 0 3 3 3 1 Regulator of chromosome condensation (RCC1) repeat Ank_3 PF13606.1 AEO59081.1 - 2.1e-06 27.4 0.2 0.02 15.0 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 AEO59081.1 - 0.00027 21.2 0.1 0.00089 19.5 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 AEO59081.1 - 0.012 15.3 0.2 0.051 13.4 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat Ank_5 PF13857.1 AEO59081.1 - 0.023 14.9 0.0 0.12 12.7 0.0 2.3 1 0 0 1 1 1 0 Ankyrin repeats (many copies) DUF3227 PF11537.3 AEO59081.1 - 0.077 13.1 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3227) Macoilin PF09726.4 AEO59081.1 - 9.1 4.4 9.9 0.5 8.5 2.6 1.8 2 0 0 2 2 2 0 Transmembrane protein ATG13 PF10033.4 AEO59082.1 - 1.4e-70 237.3 0.0 2.7e-70 236.4 0.0 1.5 1 0 0 1 1 1 1 Autophagy-related protein 13 Mucin PF01456.12 AEO59082.1 - 6.9 6.4 34.9 0.6 9.8 20.0 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein ADIP PF11559.3 AEO59083.1 - 0.0013 18.6 4.2 0.0016 18.3 2.9 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding IncA PF04156.9 AEO59083.1 - 0.0014 18.3 2.6 0.0016 18.0 1.8 1.0 1 0 0 1 1 1 1 IncA protein bZIP_1 PF00170.16 AEO59083.1 - 0.0027 17.6 5.6 0.12 12.3 1.9 2.4 2 0 0 2 2 2 1 bZIP transcription factor Cast PF10174.4 AEO59083.1 - 0.0063 14.6 3.4 0.0078 14.3 2.4 1.1 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone FimP PF09766.4 AEO59083.1 - 0.0083 15.2 0.3 0.0096 15.0 0.2 1.0 1 0 0 1 1 1 1 Fms-interacting protein ERM PF00769.14 AEO59083.1 - 0.01 15.3 2.8 0.012 15.1 1.9 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DivIC PF04977.10 AEO59083.1 - 0.012 15.0 3.1 0.012 15.0 2.1 1.8 1 1 1 2 2 2 0 Septum formation initiator ATG16 PF08614.6 AEO59083.1 - 0.017 14.9 3.2 0.021 14.6 2.2 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) APG6 PF04111.7 AEO59083.1 - 0.019 14.0 2.1 0.021 13.8 1.5 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 TMF_TATA_bd PF12325.3 AEO59083.1 - 0.02 14.6 2.1 0.024 14.3 1.5 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding COG5 PF10392.4 AEO59083.1 - 0.024 14.6 0.4 0.032 14.1 0.3 1.3 1 0 0 1 1 1 0 Golgi transport complex subunit 5 E2R135 PF11570.3 AEO59083.1 - 0.024 14.7 2.1 0.031 14.3 1.4 1.1 1 0 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 zf-C4H2 PF10146.4 AEO59083.1 - 0.027 14.4 1.7 0.033 14.1 1.2 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein DUF812 PF05667.6 AEO59083.1 - 0.03 12.8 2.2 0.032 12.7 1.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) TBPIP PF07106.8 AEO59083.1 - 0.032 13.7 1.0 0.041 13.4 0.7 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF972 PF06156.8 AEO59083.1 - 0.043 14.1 0.5 0.06 13.6 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) U79_P34 PF03064.11 AEO59083.1 - 0.044 13.3 2.4 0.045 13.2 1.7 1.0 1 0 0 1 1 1 0 HSV U79 / HCMV P34 TMF_DNA_bd PF12329.3 AEO59083.1 - 0.046 13.5 4.5 0.075 12.8 3.1 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Tektin PF03148.9 AEO59083.1 - 0.047 12.2 3.8 0.059 11.9 2.6 1.1 1 0 0 1 1 1 0 Tektin family FlxA PF14282.1 AEO59083.1 - 0.05 13.5 0.5 0.091 12.7 0.3 1.4 1 1 0 1 1 1 0 FlxA-like protein Sipho_Gp157 PF05565.6 AEO59083.1 - 0.057 13.0 2.5 0.078 12.5 1.7 1.2 1 0 0 1 1 1 0 Siphovirus Gp157 HAUS5 PF14817.1 AEO59083.1 - 0.073 11.6 2.5 0.081 11.4 1.8 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Seryl_tRNA_N PF02403.17 AEO59083.1 - 0.08 12.9 1.7 0.12 12.4 1.2 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain HALZ PF02183.13 AEO59083.1 - 0.097 12.4 2.4 1.7 8.4 0.0 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper Vps53_N PF04100.7 AEO59083.1 - 0.11 11.2 0.1 0.12 11.1 0.1 1.0 1 0 0 1 1 1 0 Vps53-like, N-terminal DUF1843 PF08898.5 AEO59083.1 - 0.13 12.3 3.8 0.23 11.5 0.1 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF1843) GAS PF13851.1 AEO59083.1 - 0.13 11.4 2.7 0.15 11.2 1.9 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding CENP-Q PF13094.1 AEO59083.1 - 0.17 11.9 4.4 0.21 11.6 3.0 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit YlqD PF11068.3 AEO59083.1 - 0.17 11.9 1.4 0.21 11.6 1.0 1.1 1 0 0 1 1 1 0 YlqD protein Mnd1 PF03962.10 AEO59083.1 - 0.17 11.5 2.5 0.2 11.3 1.8 1.1 1 0 0 1 1 1 0 Mnd1 family DUF2681 PF10883.3 AEO59083.1 - 0.17 12.0 0.8 0.22 11.7 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) DUF2968 PF11180.3 AEO59083.1 - 0.2 11.0 3.2 0.23 10.8 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) FTO_CTD PF12934.2 AEO59083.1 - 0.21 11.1 1.4 0.26 10.8 0.9 1.1 1 0 0 1 1 1 0 FTO C-terminal domain Prefoldin_2 PF01920.15 AEO59083.1 - 0.24 11.1 3.7 1.3 8.7 0.2 2.0 1 1 1 2 2 2 0 Prefoldin subunit Atg14 PF10186.4 AEO59083.1 - 0.34 9.8 5.5 0.37 9.6 3.8 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Wbp11 PF09429.5 AEO59083.1 - 0.44 10.5 7.1 1.9 8.5 4.9 2.0 1 1 0 1 1 1 0 WW domain binding protein 11 Cep57_CLD_2 PF14197.1 AEO59083.1 - 0.59 10.1 7.5 1 9.3 2.7 2.5 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 CENP-H PF05837.7 AEO59083.1 - 0.63 10.2 3.6 0.78 9.9 2.5 1.1 1 0 0 1 1 1 0 Centromere protein H (CENP-H) bZIP_2 PF07716.10 AEO59083.1 - 0.95 9.3 7.7 3.7 7.4 0.2 2.5 1 1 1 2 2 2 0 Basic region leucine zipper DUF1192 PF06698.6 AEO59083.1 - 1.3 8.8 7.6 0.53 10.1 2.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) DUF904 PF06005.7 AEO59083.1 - 1.5 9.1 4.9 3.5 7.9 3.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DUF4200 PF13863.1 AEO59083.1 - 1.7 8.6 6.6 3.4 7.6 4.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DUF883 PF05957.8 AEO59083.1 - 4.2 7.8 7.5 13 6.2 5.2 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) BUD22 PF09073.5 AEO59086.1 - 4.4e-69 233.6 72.6 1.1e-67 228.9 50.3 2.6 1 1 0 1 1 1 1 BUD22 Alpha_GJ PF03229.8 AEO59086.1 - 0.039 14.2 0.2 0.086 13.1 0.0 1.6 2 0 0 2 2 2 0 Alphavirus glycoprotein J EF-hand_1 PF00036.27 AEO59087.1 - 2.5e-21 73.3 7.8 1.3e-07 30.4 0.1 3.2 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 AEO59087.1 - 1e-19 70.3 1.1 8.5e-12 45.0 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 AEO59087.1 - 1.1e-19 68.4 6.6 1.4e-07 30.7 0.3 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 AEO59087.1 - 1.6e-18 66.0 4.5 3.1e-09 36.3 0.2 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 AEO59087.1 - 1.3e-12 46.4 9.5 2.2e-05 23.5 0.4 3.5 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.1 AEO59087.1 - 4.5e-06 26.4 0.0 0.00012 21.9 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain Caleosin PF05042.8 AEO59087.1 - 0.0046 16.5 0.0 0.3 10.6 0.0 2.1 2 0 0 2 2 2 1 Caleosin related protein EFhand_Ca_insen PF08726.5 AEO59087.1 - 0.03 14.3 0.0 0.083 12.8 0.0 1.7 1 0 0 1 1 1 0 Ca2+ insensitive EF hand EF-hand_4 PF12763.2 AEO59087.1 - 0.037 13.7 0.1 0.55 9.9 0.0 2.3 2 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand EF-hand_like PF09279.6 AEO59087.1 - 0.039 13.9 0.2 0.45 10.5 0.0 2.2 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like p450 PF00067.17 AEO59089.1 - 2.4e-43 148.3 0.0 3.2e-40 138.0 0.0 2.5 2 1 0 2 2 2 2 Cytochrome P450 CDC45 PF02724.9 AEO59089.1 - 0.68 7.8 5.1 1.2 7.0 3.5 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF4611 PF15387.1 AEO59089.1 - 0.77 9.9 11.0 20 5.4 7.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) FimP PF09766.4 AEO59089.1 - 1.2 8.0 4.0 1.8 7.5 2.7 1.2 1 0 0 1 1 1 0 Fms-interacting protein Bd3614_N PF14442.1 AEO59089.1 - 1.4 8.8 8.0 21 5.0 4.1 2.4 2 0 0 2 2 2 0 Bd3614-like deaminase N-terminal Sigma70_ner PF04546.8 AEO59089.1 - 2.9 7.4 14.1 2.9 7.4 7.3 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 AEO59089.1 - 3.2 7.2 12.2 5.6 6.4 8.5 1.3 1 0 0 1 1 1 0 Nucleoplasmin PEPCK_ATP PF01293.15 AEO59091.1 - 1.5e-218 725.9 0.0 1.8e-218 725.7 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_18 PF13238.1 AEO59091.1 - 0.0095 16.2 0.1 4.2 7.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 AEO59091.1 - 0.073 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 AEO59091.1 - 0.1 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 AEO59091.1 - 0.18 11.3 0.5 0.44 10.1 0.4 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF1295 PF06966.7 AEO59092.1 - 3.4e-29 101.8 6.9 8.4e-28 97.2 4.8 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.11 AEO59092.1 - 0.00098 18.9 0.1 0.0023 17.6 0.1 1.6 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 AEO59092.1 - 0.0054 16.8 1.0 0.21 11.7 0.0 3.3 2 1 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.9 AEO59092.1 - 0.081 13.1 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Cupin_8 PF13621.1 AEO59093.1 - 8.4e-25 87.7 0.0 1.3e-24 87.1 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 AEO59093.1 - 0.006 16.8 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase CK_II_beta PF01214.13 AEO59094.1 - 3.3e-77 258.1 0.0 5.3e-77 257.4 0.0 1.3 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Spt5_N PF11942.3 AEO59094.1 - 0.0058 17.2 4.9 0.0058 17.2 3.4 2.3 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal Sporozoite_P67 PF05642.6 AEO59094.1 - 0.077 10.8 0.4 0.13 10.0 0.3 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RRN3 PF05327.6 AEO59094.1 - 0.29 9.1 0.6 0.41 8.7 0.4 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PGA2 PF07543.7 AEO59094.1 - 0.77 9.5 5.1 0.21 11.3 1.2 1.6 2 0 0 2 2 2 0 Protein trafficking PGA2 Nucleoplasmin PF03066.10 AEO59094.1 - 2.2 7.8 11.0 0.68 9.4 4.5 2.0 2 0 0 2 2 2 0 Nucleoplasmin PBP1_TM PF14812.1 AEO59094.1 - 6.9 7.0 13.7 8.7 6.7 3.3 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ABC2_membrane PF01061.19 AEO59095.1 - 2.1e-79 265.5 48.3 5.6e-41 140.0 13.0 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 AEO59095.1 - 7.9e-37 126.6 0.0 2.1e-17 63.6 0.0 2.7 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 AEO59095.1 - 1.3e-27 95.4 1.2 1.3e-24 85.8 0.0 3.1 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.1 AEO59095.1 - 4.3e-09 36.3 0.0 1.8e-08 34.3 0.0 2.1 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 AEO59095.1 - 2e-08 33.6 24.1 6.8e-05 22.0 4.2 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_33 PF13671.1 AEO59095.1 - 7.2e-07 29.1 0.9 0.0018 18.1 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_25 PF13481.1 AEO59095.1 - 4.5e-06 26.1 0.5 0.0042 16.5 0.1 2.8 3 0 0 3 3 2 2 AAA domain AAA_17 PF13207.1 AEO59095.1 - 6.2e-06 27.0 0.0 0.011 16.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 AEO59095.1 - 8e-06 25.9 0.1 0.0045 16.9 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.1 AEO59095.1 - 2.5e-05 24.3 0.0 0.077 12.9 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 AEO59095.1 - 3.7e-05 23.8 0.1 0.25 11.4 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 AEO59095.1 - 4e-05 23.0 0.2 0.0032 16.9 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.1 AEO59095.1 - 9.4e-05 22.4 0.1 0.018 14.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 AEO59095.1 - 0.00012 21.5 2.0 0.01 15.3 0.4 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 AEO59095.1 - 0.00019 21.0 0.6 0.26 11.0 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain UPF0079 PF02367.12 AEO59095.1 - 0.00025 20.6 1.1 0.55 9.8 0.1 2.4 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 DUF258 PF03193.11 AEO59095.1 - 0.00047 19.3 0.0 0.0028 16.8 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 NACHT PF05729.7 AEO59095.1 - 0.0027 17.3 0.8 1.4 8.5 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_18 PF13238.1 AEO59095.1 - 0.0028 17.9 0.0 0.38 11.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 AEO59095.1 - 0.0052 16.0 0.0 1.2 8.3 0.0 3.1 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.13 AEO59095.1 - 0.011 15.1 0.1 1 8.7 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_10 PF12846.2 AEO59095.1 - 0.015 14.7 0.1 0.96 8.8 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_14 PF13173.1 AEO59095.1 - 0.024 14.5 0.7 5.7 6.8 0.0 3.2 4 0 0 4 4 2 0 AAA domain Miro PF08477.8 AEO59095.1 - 0.035 14.6 0.0 7.6 7.0 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein PduV-EutP PF10662.4 AEO59095.1 - 0.062 12.7 1.0 2.2 7.7 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.1 AEO59095.1 - 0.084 12.4 0.1 3.9 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 AEO59095.1 - 0.1 12.7 0.4 13 5.9 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 AEO59095.1 - 0.14 11.7 0.8 8.6 5.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 AEO59095.1 - 0.19 11.2 0.0 0.82 9.1 0.0 2.0 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_23 PF13476.1 AEO59095.1 - 0.43 10.8 0.0 0.43 10.8 0.0 2.7 4 0 0 4 4 2 0 AAA domain DND1_DSRM PF14709.1 AEO59096.1 - 0.065 13.5 0.0 0.11 12.7 0.0 1.5 2 0 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 ELM2 PF01448.19 AEO59096.1 - 0.091 13.4 0.0 0.14 12.8 0.0 1.3 1 0 0 1 1 1 0 ELM2 domain CobT PF06213.7 AEO59097.1 - 0.0043 16.2 9.1 0.24 10.5 0.3 2.3 2 0 0 2 2 2 2 Cobalamin biosynthesis protein CobT RRM_1 PF00076.17 AEO59098.1 - 5e-10 38.8 0.1 9.6e-10 37.9 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO59098.1 - 1.8e-08 34.2 0.0 3.6e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO59098.1 - 0.0013 18.5 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 AEO59098.1 - 0.0019 18.0 0.0 0.0047 16.7 0.0 1.6 1 0 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.1 AEO59098.1 - 0.0072 16.0 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif ANTH PF07651.11 AEO59098.1 - 0.052 12.2 0.0 0.14 10.8 0.0 1.7 2 0 0 2 2 2 0 ANTH domain Striatin PF08232.7 AEO59100.1 - 0.0045 17.3 7.7 0.092 13.0 4.4 2.2 2 0 0 2 2 2 1 Striatin family BAF1_ABF1 PF04684.8 AEO59100.1 - 0.017 14.0 6.4 0.028 13.3 4.5 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor TAF4 PF05236.9 AEO59100.1 - 0.067 12.4 6.6 0.12 11.6 4.6 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DUF2361 PF10153.4 AEO59100.1 - 0.26 11.4 3.9 0.59 10.3 2.7 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2361) WD40 PF00400.27 AEO59102.1 - 0.0062 16.3 0.4 1.3 9.0 0.0 3.7 3 0 0 3 3 3 1 WD domain, G-beta repeat PQQ_3 PF13570.1 AEO59102.1 - 0.014 15.6 0.0 0.08 13.2 0.0 2.4 1 1 0 1 1 1 0 PQQ-like domain UT PF03253.9 AEO59103.1 - 0.037 12.9 0.0 0.04 12.8 0.0 1.0 1 0 0 1 1 1 0 Urea transporter DUF2868 PF11067.3 AEO59103.1 - 0.12 11.5 0.0 0.12 11.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) HgmA PF04209.8 AEO59105.1 - 2.1e-171 570.0 0.0 2.4e-171 569.8 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Methyltransf_23 PF13489.1 AEO59106.1 - 2.5e-24 85.8 0.0 4.6e-24 84.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO59106.1 - 3.4e-13 49.9 0.0 1.5e-12 47.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO59106.1 - 7.2e-13 48.8 0.0 1.7e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO59106.1 - 2e-11 43.7 0.0 7.4e-11 41.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO59106.1 - 5.4e-11 43.0 0.0 5.2e-10 39.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO59106.1 - 1.9e-07 31.3 0.0 5.6e-07 29.8 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 AEO59106.1 - 2.4e-05 23.6 0.0 3.6e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Ubie_methyltran PF01209.13 AEO59106.1 - 4.1e-05 22.7 0.0 0.00032 19.8 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 AEO59106.1 - 0.00044 20.2 0.0 0.0016 18.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AEO59106.1 - 0.00052 19.4 0.0 0.0018 17.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 AEO59106.1 - 0.0012 18.8 0.0 0.0021 18.1 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.8 AEO59106.1 - 0.012 14.7 0.0 0.023 13.8 0.0 1.4 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 AEO59106.1 - 0.055 12.5 0.0 0.35 9.8 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_PK PF05891.7 AEO59106.1 - 0.078 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Nop14 PF04147.7 AEO59106.1 - 0.11 10.3 12.5 0.13 10.1 8.7 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 AEO59106.1 - 0.18 10.2 10.6 0.24 9.8 7.4 1.1 1 0 0 1 1 1 0 Daxx Family Sporozoite_P67 PF05642.6 AEO59106.1 - 0.44 8.3 6.7 0.58 7.9 4.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.9 AEO59106.1 - 0.55 8.2 7.0 0.75 7.7 4.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Voldacs PF03517.8 AEO59106.1 - 1 9.1 7.5 2.2 8.1 5.2 1.6 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling RRN3 PF05327.6 AEO59106.1 - 2.1 6.3 3.7 3.1 5.7 2.5 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PPP4R2 PF09184.6 AEO59106.1 - 2.7 7.4 13.5 4.1 6.8 9.4 1.2 1 0 0 1 1 1 0 PPP4R2 SDA1 PF05285.7 AEO59106.1 - 3.2 6.9 11.7 4.2 6.5 8.1 1.1 1 0 0 1 1 1 0 SDA1 TFIIF_alpha PF05793.7 AEO59106.1 - 3.5 5.8 11.7 4.7 5.4 8.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BUD22 PF09073.5 AEO59106.1 - 3.9 6.4 8.5 4.7 6.1 5.9 1.1 1 0 0 1 1 1 0 BUD22 Myc_N PF01056.13 AEO59106.1 - 4 6.5 10.9 7.1 5.7 7.6 1.4 1 0 0 1 1 1 0 Myc amino-terminal region Nucleoplasmin PF03066.10 AEO59106.1 - 4.1 6.8 19.8 7.8 6.0 13.8 1.3 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 AEO59106.1 - 5.4 6.1 13.9 9.6 5.3 9.6 1.3 1 0 0 1 1 1 0 NOA36 protein CobT PF06213.7 AEO59106.1 - 8.4 5.4 16.5 14 4.6 11.4 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DAO PF01266.19 AEO59107.1 - 1.1e-45 156.1 11.8 2.4e-45 155.0 8.2 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 AEO59107.1 - 0.0013 18.8 0.5 0.95 9.4 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AEO59107.1 - 0.0015 18.5 1.1 0.0015 18.5 0.7 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 AEO59107.1 - 0.035 13.8 0.2 0.088 12.5 0.1 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding DAP_B PF07930.7 AEO59108.1 - 0.052 13.2 0.3 0.16 11.7 0.0 2.0 2 0 0 2 2 2 0 D-aminopeptidase, domain B dCMP_cyt_deam_1 PF00383.17 AEO59112.1 - 3.7e-08 32.9 0.0 5.3e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Methyltransf_16 PF10294.4 AEO59113.1 - 5.6e-29 100.8 0.0 9.7e-29 100.0 0.0 1.4 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 AEO59113.1 - 0.00045 20.7 0.0 0.00078 20.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO59113.1 - 0.0035 17.0 0.0 0.007 16.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AEO59113.1 - 0.026 13.9 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.1 AEO59113.1 - 0.028 13.9 0.0 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 AEO59113.1 - 0.061 13.8 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RCC1 PF00415.13 AEO59115.1 - 4.7e-64 212.4 0.8 8.4e-09 35.5 0.0 7.6 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 AEO59115.1 - 1.7e-36 123.0 27.1 1.9e-07 30.5 0.4 6.3 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat CBM_X PF06204.6 AEO59115.1 - 0.0016 17.8 1.1 0.48 9.9 0.1 2.8 2 0 0 2 2 2 2 Putative carbohydrate binding domain Nucleo_P87 PF07267.6 AEO59115.1 - 7.2 5.1 5.8 10 4.6 4.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Yip1 PF04893.12 AEO59116.1 - 2.1e-07 30.5 18.7 0.00038 20.0 7.1 2.7 2 1 1 3 3 3 2 Yip1 domain Pam16 PF03656.8 AEO59117.1 - 5.6e-35 119.9 0.5 6.8e-35 119.6 0.3 1.0 1 0 0 1 1 1 1 Pam16 BPL_N PF09825.4 AEO59119.1 - 9.1e-144 478.7 0.0 1.1e-143 478.4 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 AEO59119.1 - 1.5e-18 67.0 0.0 3.8e-18 65.7 0.0 1.7 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DUF2757 PF10955.3 AEO59119.1 - 0.0039 17.3 0.0 0.014 15.5 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2757) CHCH PF06747.8 AEO59120.1 - 2.1e-06 27.4 5.0 3.1e-06 26.9 3.5 1.3 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 AEO59120.1 - 0.018 14.8 4.5 0.045 13.5 3.1 1.6 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Mgm101p PF06420.7 AEO59121.1 - 3.7e-91 303.0 0.0 4.9e-91 302.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 TB2_DP1_HVA22 PF03134.14 AEO59122.1 - 5.5e-30 102.9 8.5 8.4e-30 102.3 5.9 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family CASP_C PF08172.7 AEO59122.1 - 0.00077 18.5 1.8 0.0016 17.5 1.2 1.4 1 0 0 1 1 1 1 CASP C terminal CAF-1_p150 PF11600.3 AEO59122.1 - 0.59 9.4 5.1 0.93 8.8 3.5 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4228 PF14009.1 AEO59122.1 - 0.89 9.6 7.1 1.5 8.9 4.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) DUF3446 PF11928.3 AEO59122.1 - 2.9 8.1 15.5 0.78 9.9 8.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) TFIIA PF03153.8 AEO59122.1 - 7 6.4 9.1 9.6 5.9 6.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MFS_1 PF07690.11 AEO59123.1 - 1e-32 113.2 28.1 4.3e-32 111.2 19.7 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily 4HBT PF03061.17 AEO59125.1 - 8.3e-12 45.0 0.1 1.2e-11 44.5 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 AEO59125.1 - 0.0018 18.0 0.0 0.0025 17.6 0.0 1.3 1 1 0 1 1 1 1 Thioesterase-like superfamily Tfb2 PF03849.9 AEO59126.1 - 7.3e-139 462.4 0.0 1.3e-138 461.6 0.0 1.4 2 0 0 2 2 2 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 AEO59126.1 - 2.6e-06 27.2 0.0 6.7e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SinI PF08671.5 AEO59126.1 - 0.084 12.3 0.2 1.1 8.7 0.0 2.6 2 0 0 2 2 2 0 Anti-repressor SinI NRDE PF05742.7 AEO59128.1 - 6e-36 124.1 0.0 9.5e-25 87.4 0.0 2.9 2 1 0 2 2 2 2 NRDE protein HMGL-like PF00682.14 AEO59130.1 - 9.4e-70 234.9 0.1 2.3e-69 233.6 0.0 1.7 1 1 1 2 2 2 1 HMGL-like Trp_syntA PF00290.15 AEO59130.1 - 0.1 11.1 0.0 7.5 5.0 0.0 2.3 2 0 0 2 2 2 0 Tryptophan synthase alpha chain adh_short PF00106.20 AEO59132.1 - 0.00016 21.5 0.0 0.024 14.5 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase Epimerase PF01370.16 AEO59132.1 - 0.018 14.5 0.0 0.058 12.8 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family SR-25 PF10500.4 AEO59132.1 - 3.4 7.0 12.6 5.4 6.4 8.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein MFS_1 PF07690.11 AEO59133.1 - 1.9e-14 53.1 55.7 6.6e-12 44.7 37.2 2.7 1 1 0 1 1 1 1 Major Facilitator Superfamily RNase_H PF00075.19 AEO59135.1 - 9.7e-06 25.9 0.0 1.6e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 RNase H FAA_hydrolase PF01557.13 AEO59136.1 - 4.6e-52 176.6 0.0 6.1e-52 176.2 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 AEO59136.1 - 3.3e-27 94.5 0.1 5.7e-27 93.8 0.1 1.4 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal Fungal_trans PF04082.13 AEO59137.1 - 1e-12 47.4 0.1 2e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PLAC8 PF04749.12 AEO59138.1 - 1.1e-21 77.3 15.3 1.4e-21 77.0 10.6 1.1 1 0 0 1 1 1 1 PLAC8 family PhaG_MnhG_YufB PF03334.9 AEO59138.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Na+/H+ antiporter subunit CPDase PF07823.6 AEO59140.1 - 9.9e-29 100.2 0.0 1.3e-28 99.8 0.0 1.1 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein Btz PF09405.5 AEO59141.1 - 0.044 13.8 0.3 0.08 12.9 0.2 1.3 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding Cytochrom_B561 PF03188.11 AEO59142.1 - 7.1e-07 29.1 7.4 1.2e-06 28.3 5.2 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 Vac14_Fig4_bd PF11916.3 AEO59142.1 - 0.0057 15.8 0.1 0.0081 15.3 0.0 1.2 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Ni_hydr_CYTB PF01292.15 AEO59142.1 - 0.0064 15.8 2.3 0.0064 15.8 1.6 2.2 1 1 1 2 2 2 1 Prokaryotic cytochrome b561 DUF2306 PF10067.4 AEO59142.1 - 0.0078 16.3 3.3 0.0078 16.3 2.3 2.3 1 1 2 3 3 3 1 Predicted membrane protein (DUF2306) Cytochrom_B_N PF00033.14 AEO59142.1 - 0.12 11.6 8.9 0.45 9.8 6.2 2.0 1 1 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB DUF2427 PF10348.4 AEO59142.1 - 0.28 10.7 6.4 0.16 11.5 3.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) AzlD PF05437.7 AEO59142.1 - 1.2 9.1 8.1 0.1 12.5 1.6 2.1 2 0 0 2 2 2 0 Branched-chain amino acid transport protein (AzlD) Pribosyltran PF00156.22 AEO59143.1 - 8.1e-10 38.4 0.2 2.4e-09 36.9 0.1 1.8 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Oxidored-like PF09791.4 AEO59144.1 - 4.7e-26 89.9 3.2 4.7e-26 89.9 2.2 2.0 2 0 0 2 2 2 1 Oxidoreductase-like protein, N-terminal MIP-T3 PF10243.4 AEO59144.1 - 0.32 9.4 16.8 0.4 9.1 11.7 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 UPF0561 PF10573.4 AEO59144.1 - 0.41 10.4 5.2 1.3 8.9 3.6 1.9 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 DUF2217 PF10265.4 AEO59144.1 - 4 6.0 12.1 5.9 5.5 8.4 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Adeno_terminal PF02459.10 AEO59145.1 - 0.55 8.3 4.7 0.85 7.7 3.2 1.2 1 0 0 1 1 1 0 Adenoviral DNA terminal protein DPM3 PF08285.6 AEO59146.1 - 2e-33 114.1 0.1 2.2e-33 113.9 0.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) LRR_4 PF12799.2 AEO59147.1 - 2.8e-37 125.7 31.0 5.2e-10 38.7 0.9 10.4 8 3 2 11 11 11 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AEO59147.1 - 6.6e-29 99.4 38.7 6.6e-08 32.1 3.8 9.1 5 2 7 12 12 12 9 Leucine rich repeat LRR_1 PF00560.28 AEO59147.1 - 4.1e-17 59.5 43.0 0.0018 18.0 0.5 15.8 16 2 0 16 16 16 5 Leucine Rich Repeat LRR_7 PF13504.1 AEO59147.1 - 1.6e-09 36.4 44.8 1.2 9.6 0.4 14.2 14 0 0 14 14 14 4 Leucine rich repeat LRR_6 PF13516.1 AEO59147.1 - 3.9e-08 32.5 32.3 5 7.5 1.6 13.1 14 1 0 14 14 14 4 Leucine Rich repeat LRR_9 PF14580.1 AEO59147.1 - 0.022 14.3 3.4 8.4 5.9 0.0 4.3 2 2 3 5 5 5 0 Leucine-rich repeat DUF605 PF04652.11 AEO59148.1 - 2.3 7.5 9.3 0.092 12.1 2.7 1.4 2 0 0 2 2 2 0 Vta1 like DNA_photolyase PF00875.13 AEO59149.1 - 0.015 15.0 0.2 0.056 13.1 0.1 1.9 2 0 0 2 2 2 0 DNA photolyase zf-AN1 PF01428.11 AEO59150.1 - 0.045 13.6 0.7 0.045 13.6 0.5 1.9 2 0 0 2 2 2 0 AN1-like Zinc finger DAHP_synth_1 PF00793.15 AEO59151.1 - 3.4e-101 337.4 0.0 4e-101 337.2 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family COX14 PF14880.1 AEO59153.1 - 2.3e-20 71.9 0.1 6.4e-20 70.5 0.1 1.8 1 0 0 1 1 1 1 Cytochrome oxidase c assembly Herpes_pp85 PF04637.7 AEO59153.1 - 0.19 9.9 4.8 0.3 9.3 3.4 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) TraQ PF09679.5 AEO59153.1 - 0.8 9.6 2.4 13 5.7 0.3 2.5 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin chaperone (TraQ) DUF572 PF04502.8 AEO59153.1 - 1.6 7.8 12.4 3.4 6.7 8.7 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF572) Ribosomal_L50 PF10501.4 AEO59154.1 - 8.2e-23 80.5 0.4 2.1e-22 79.1 0.3 1.8 1 1 0 1 1 1 1 Ribosomal subunit 39S DUF853 PF05872.7 AEO59154.1 - 0.0091 14.3 4.5 0.014 13.7 3.1 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF853) DUF4652 PF15525.1 AEO59154.1 - 0.41 10.0 6.2 5.4 6.3 3.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4652) Ribosomal_L13e PF01294.13 AEO59155.1 - 8.6e-65 217.5 3.9 1.1e-64 217.1 2.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e VWA_CoxE PF05762.9 AEO59156.1 - 0.0059 15.7 0.0 0.0092 15.1 0.0 1.2 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein Thiolase_N PF00108.18 AEO59157.1 - 1.3e-73 247.2 0.2 1.8e-73 246.7 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 AEO59157.1 - 5.2e-41 138.9 1.9 1.3e-40 137.6 1.3 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain Phage_tube PF04985.9 AEO59157.1 - 0.1 12.0 0.1 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Phage tail tube protein FII DUF972 PF06156.8 AEO59158.1 - 0.31 11.4 10.1 1.2 9.4 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF972) HALZ PF02183.13 AEO59158.1 - 1.8 8.3 6.6 0.28 10.9 1.0 2.5 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF940 PF06082.6 AEO59158.1 - 3.1 6.2 4.6 4.6 5.6 3.2 1.2 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) Cu-oxidase_3 PF07732.10 AEO59159.1 - 3.5e-30 104.1 0.1 6.9e-29 99.9 0.0 2.6 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 AEO59159.1 - 8.9e-27 93.9 0.0 6.7e-26 91.0 0.0 2.2 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 AEO59159.1 - 1.5e-26 92.5 7.2 1.4e-24 86.1 1.0 3.5 2 2 0 2 2 2 2 Multicopper oxidase DUF3818 PF12825.2 AEO59160.1 - 3.7e-37 127.7 0.3 3.6e-27 94.9 0.0 2.3 1 1 1 2 2 2 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 AEO59160.1 - 1.3e-32 112.2 0.0 2.5e-32 111.3 0.0 1.4 1 0 0 1 1 1 1 PX-associated Pex24p PF06398.6 AEO59163.1 - 2.7e-104 348.8 0.0 3.7e-104 348.3 0.0 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Acetyltransf_1 PF00583.19 AEO59165.1 - 6.2e-08 32.5 0.2 1.1e-07 31.8 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 AEO59165.1 - 0.00015 21.4 0.0 0.00025 20.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 AEO59165.1 - 0.00054 20.0 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 AEO59165.1 - 0.05 13.4 0.0 0.093 12.6 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 AEO59165.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CobU PF02283.11 AEO59168.1 - 0.0096 15.3 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 1 Cobinamide kinase / cobinamide phosphate guanyltransferase Melibiase PF02065.13 AEO59170.1 - 4.2e-16 58.6 0.0 3.4e-13 49.0 0.0 2.9 3 0 0 3 3 3 3 Melibiase MFS_1 PF07690.11 AEO59172.1 - 1.4e-47 162.0 39.1 1.4e-47 162.0 27.1 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO59172.1 - 1.2e-16 60.3 7.3 1.2e-16 60.3 5.0 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 AEO59172.1 - 0.00027 19.2 4.4 0.00027 19.2 3.1 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 AEO59172.1 - 0.00092 17.4 2.5 0.00092 17.4 1.7 1.7 2 0 0 2 2 2 1 Transmembrane secretion effector 60KD_IMP PF02096.15 AEO59172.1 - 3 7.4 6.8 3.8 7.1 1.1 3.3 2 1 1 3 3 3 0 60Kd inner membrane protein Peptidase_A4 PF01828.12 AEO59176.1 - 1.4e-19 69.9 2.4 2e-19 69.5 1.7 1.1 1 0 0 1 1 1 1 Peptidase A4 family Sugar_tr PF00083.19 AEO59178.1 - 3.2e-78 263.3 23.1 4e-78 262.9 16.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO59178.1 - 2.3e-14 52.8 60.2 2.7e-12 46.0 20.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MgtE PF01769.11 AEO59178.1 - 0.036 14.3 0.5 0.036 14.3 0.4 3.0 2 1 1 3 3 3 0 Divalent cation transporter Ldh_2 PF02615.9 AEO59179.1 - 2.7e-97 325.4 0.0 3.1e-97 325.3 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Actin PF00022.14 AEO59180.1 - 1.3e-104 349.7 0.0 1.6e-104 349.4 0.0 1.0 1 0 0 1 1 1 1 Actin PAP_assoc PF03828.14 AEO59181.1 - 3.4e-14 52.5 0.1 7.2e-14 51.4 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 AEO59181.1 - 1.7e-08 34.7 0.0 3.6e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Sugar_tr PF00083.19 AEO59182.1 - 2.9e-107 359.0 18.5 3.9e-107 358.6 12.8 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO59182.1 - 6.5e-21 74.4 22.5 6.5e-21 74.4 15.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 AEO59182.1 - 0.0025 16.0 6.2 0.0051 14.9 4.3 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector DUF554 PF04474.7 AEO59182.1 - 0.6 9.2 8.7 0.039 13.0 2.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF554) PS-DH PF14765.1 AEO59185.1 - 2.4e-09 36.8 0.0 3e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Polyketide synthase dehydratase DUF4379 PF14311.1 AEO59185.1 - 0.067 13.0 0.8 0.12 12.2 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4379) Aldo_ket_red PF00248.16 AEO59186.1 - 1.6e-69 233.9 0.0 2.1e-69 233.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_2_N PF02837.13 AEO59187.1 - 6e-08 32.4 0.0 1.1e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 AEO59187.1 - 6.6e-05 23.3 0.0 0.00015 22.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 AEO59187.1 - 0.00026 19.9 0.0 0.00046 19.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bac_surface_Ag PF01103.18 AEO59188.1 - 1.6e-39 136.2 0.0 2.2e-39 135.7 0.0 1.2 1 0 0 1 1 1 1 Surface antigen UQ_con PF00179.21 AEO59189.1 - 5.4e-26 90.6 0.1 7.3e-26 90.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme ABC2_membrane PF01061.19 AEO59190.1 - 6.9e-98 325.9 57.2 3.1e-50 170.2 14.1 2.8 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.7 AEO59190.1 - 8.9e-38 128.1 0.7 2e-34 117.3 0.0 3.3 4 0 0 4 4 2 2 CDR ABC transporter ABC_tran PF00005.22 AEO59190.1 - 6e-34 117.2 0.0 2.4e-16 60.2 0.0 2.9 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.1 AEO59190.1 - 1.3e-22 79.6 0.0 3.2e-22 78.4 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 AEO59190.1 - 3e-07 30.0 0.0 0.00091 18.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 AEO59190.1 - 4.7e-07 29.9 0.1 7.7e-05 22.7 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 AEO59190.1 - 7.8e-06 25.8 0.0 0.026 14.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 AEO59190.1 - 1.4e-05 24.3 0.0 0.00015 21.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 cobW PF02492.14 AEO59190.1 - 2.4e-05 23.8 0.1 0.005 16.3 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 AEO59190.1 - 8e-05 23.4 0.0 1.1 10.0 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 AEO59190.1 - 0.00014 22.0 0.0 0.53 10.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.2 AEO59190.1 - 0.00029 19.9 40.5 0.013 14.5 11.4 3.2 2 2 0 2 2 2 2 ABC-2 family transporter protein AAA_19 PF13245.1 AEO59190.1 - 0.0006 19.5 0.1 0.46 10.2 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain AAA_29 PF13555.1 AEO59190.1 - 0.00076 18.9 0.5 0.026 14.0 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.1 AEO59190.1 - 0.0012 18.9 0.0 1.2 8.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 AEO59190.1 - 0.0035 17.0 0.1 3 7.4 0.1 2.6 2 0 0 2 2 2 2 NACHT domain UPF0079 PF02367.12 AEO59190.1 - 0.0068 16.0 0.2 3.9 7.1 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 AEO59190.1 - 0.016 15.5 0.0 0.85 9.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 AEO59190.1 - 0.017 15.0 0.1 1.7 8.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain SMC_N PF02463.14 AEO59190.1 - 0.021 14.0 0.0 1.6 7.9 0.0 3.1 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA PF00004.24 AEO59190.1 - 0.024 14.8 0.1 5.4 7.2 0.0 3.0 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 AEO59190.1 - 0.1 12.4 0.0 12 5.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 AEO59190.1 - 0.13 11.6 0.0 11 5.4 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_23 PF13476.1 AEO59190.1 - 0.17 12.2 0.2 0.47 10.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.1 AEO59190.1 - 0.22 11.0 0.6 10 5.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Aldo_ket_red PF00248.16 AEO59192.1 - 1.8e-46 158.2 0.0 2.2e-45 154.7 0.0 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family DUF4596 PF15363.1 AEO59193.1 - 0.096 12.6 0.3 1.5 8.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4596) DOMON PF03351.12 AEO59193.1 - 0.098 12.5 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 DOMON domain Sugar_tr PF00083.19 AEO59194.1 - 6.2e-89 298.6 15.3 7e-89 298.4 10.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO59194.1 - 9.6e-21 73.8 44.3 2.6e-16 59.2 13.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_M28 PF04389.12 AEO59195.1 - 8.1e-39 133.2 0.1 1.2e-38 132.6 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 AEO59195.1 - 1.2e-08 34.6 0.8 2.3e-08 33.7 0.1 1.7 1 1 1 2 2 2 1 Peptidase family M20/M25/M40 Nicastrin PF05450.10 AEO59195.1 - 0.00015 21.0 0.2 0.0039 16.4 0.0 2.2 2 0 0 2 2 2 1 Nicastrin Peptidase_M42 PF05343.9 AEO59195.1 - 0.009 14.8 0.0 0.062 12.0 0.0 2.0 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase RhgB_N PF09284.5 AEO59196.1 - 4.6e-121 402.8 5.7 7.3e-121 402.2 4.0 1.3 1 0 0 1 1 1 1 Rhamnogalacturonase B, N-terminal CBM-like PF14683.1 AEO59196.1 - 1.6e-58 197.0 0.0 3.7e-58 195.8 0.0 1.7 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 AEO59196.1 - 1.9e-17 63.1 2.0 4.3e-17 62.0 1.4 1.6 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 AEO59196.1 - 6.7e-06 26.0 1.9 6.7e-06 26.0 1.3 3.6 6 0 0 6 6 6 1 Carboxypeptidase regulatory-like domain DUF2012 PF09430.5 AEO59196.1 - 0.0069 16.2 0.0 0.017 14.9 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2012) PEGA PF08308.6 AEO59196.1 - 0.049 13.4 1.0 0.2 11.4 0.0 2.5 3 0 0 3 3 3 0 PEGA domain DUF4480 PF13715.1 AEO59196.1 - 0.071 13.1 0.9 0.36 10.9 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4480) HTH_7 PF02796.10 AEO59196.1 - 0.09 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Ribosomal_S28e PF01200.13 AEO59197.1 - 5.1e-31 106.2 1.7 5.4e-31 106.1 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Glyco_hydro_71 PF03659.9 AEO59198.1 - 5.2e-116 387.2 0.0 6.5e-116 386.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 ABC1 PF03109.11 AEO59199.1 - 3.5e-27 94.7 0.0 1.7e-17 63.4 0.0 2.5 1 1 1 2 2 2 2 ABC1 family APH PF01636.18 AEO59199.1 - 0.0068 16.1 1.6 0.032 13.9 0.3 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Cyto_heme_lyase PF01265.12 AEO59200.1 - 1.5e-76 257.4 0.0 1.7e-76 257.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Methyltransf_23 PF13489.1 AEO59202.1 - 9.3e-19 67.7 0.0 1.3e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO59202.1 - 1.2e-08 35.3 0.0 8.5e-08 32.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO59202.1 - 9.4e-08 32.6 0.0 1.5e-06 28.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO59202.1 - 4.6e-07 29.5 0.0 5.2e-06 26.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO59202.1 - 1.5e-05 25.3 0.0 4.3e-05 23.9 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 AEO59202.1 - 0.00066 19.1 0.0 0.001 18.5 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_4 PF02390.12 AEO59202.1 - 0.0023 17.0 0.0 0.0042 16.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 AEO59202.1 - 0.0036 17.3 0.0 0.0042 17.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AEO59202.1 - 0.0045 16.3 0.0 0.0084 15.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 AEO59202.1 - 0.0048 17.2 0.0 0.011 16.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 AEO59202.1 - 0.017 15.1 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.8 AEO59202.1 - 0.031 13.3 0.0 0.051 12.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 AEO59202.1 - 0.039 13.0 0.0 0.28 10.2 0.0 2.0 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase SepZ PF06066.6 AEO59204.1 - 0.0095 15.9 1.0 0.023 14.7 0.4 1.8 2 0 0 2 2 2 1 SepZ GCIP PF13324.1 AEO59206.1 - 6.1e-05 22.3 0.4 0.00066 18.9 0.1 2.4 2 0 0 2 2 2 1 Grap2 and cyclin-D-interacting FlxA PF14282.1 AEO59206.1 - 0.0047 16.8 0.8 0.022 14.7 0.1 2.0 2 0 0 2 2 2 1 FlxA-like protein DUF883 PF05957.8 AEO59206.1 - 0.033 14.5 0.8 0.94 9.9 0.1 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) KAR9 PF08580.5 AEO59206.1 - 0.074 11.3 0.2 0.12 10.6 0.1 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 PRKCSH-like PF12999.2 AEO59207.1 - 2.9e-37 127.9 12.7 3.1e-23 82.2 0.9 3.5 3 1 0 4 4 4 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 AEO59207.1 - 1.9e-32 111.8 1.3 1.9e-32 111.8 0.9 2.1 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 AEO59207.1 - 6.1e-11 42.9 0.5 1.9e-10 41.3 0.3 1.9 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein DUF4047 PF13256.1 AEO59207.1 - 0.024 14.6 10.7 0.85 9.5 3.8 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4047) NPV_P10 PF05531.7 AEO59207.1 - 0.041 14.1 2.1 0.12 12.6 0.1 2.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Mig-14 PF07395.6 AEO59207.1 - 0.041 12.8 2.2 0.083 11.8 1.5 1.4 1 0 0 1 1 1 0 Mig-14 PspB PF06667.7 AEO59207.1 - 0.057 13.3 0.3 0.057 13.3 0.2 2.4 2 0 0 2 2 2 0 Phage shock protein B Ehrlichia_rpt PF09528.5 AEO59207.1 - 0.097 10.7 2.9 0.28 9.2 1.9 1.6 1 1 0 1 1 1 0 Ehrlichia tandem repeat (Ehrlichia_rpt) Prefoldin_2 PF01920.15 AEO59207.1 - 0.12 12.1 20.6 0.91 9.3 4.3 3.9 3 1 0 3 3 3 0 Prefoldin subunit DUF3086 PF11285.3 AEO59207.1 - 0.13 11.0 0.0 0.13 11.0 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3086) Fmp27_WPPW PF10359.4 AEO59207.1 - 0.4 9.0 6.2 0.54 8.6 2.0 2.1 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Spc24 PF08286.6 AEO59207.1 - 0.43 10.2 11.8 1 9.1 1.3 3.7 3 1 1 4 4 4 0 Spc24 subunit of Ndc80 Lectin_N PF03954.9 AEO59207.1 - 0.6 9.5 2.7 5.5 6.3 0.0 2.3 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain MAD PF05557.8 AEO59207.1 - 1 7.3 17.1 0.18 9.8 8.9 1.7 2 0 0 2 2 2 0 Mitotic checkpoint protein WXG100 PF06013.7 AEO59207.1 - 1.7 8.7 4.4 57 3.8 0.1 3.3 3 0 0 3 3 3 0 Proteins of 100 residues with WXG Oxysterol_BP PF01237.13 AEO59207.1 - 1.8 6.9 4.8 1.4 7.3 0.1 2.1 2 0 0 2 2 2 0 Oxysterol-binding protein Fib_alpha PF08702.5 AEO59207.1 - 3.5 7.7 7.1 7.1 6.7 0.1 2.7 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Filament PF00038.16 AEO59207.1 - 3.8 6.8 23.6 76 2.6 13.1 2.9 2 1 0 2 2 2 0 Intermediate filament protein GAS PF13851.1 AEO59207.1 - 4.1 6.5 22.1 1.4 8.0 0.1 2.8 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Viral_P18 PF04521.8 AEO59207.1 - 8.2 5.9 10.6 0.67 9.4 1.0 2.9 3 1 0 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein FadA PF09403.5 AEO59207.1 - 8.4 6.4 15.9 0.67 9.9 0.1 3.1 3 0 0 3 3 3 0 Adhesion protein FadA Rtf2 PF04641.7 AEO59208.1 - 1.1e-51 175.5 0.1 1.4e-51 175.2 0.1 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_UBOX PF13445.1 AEO59208.1 - 8.4e-05 22.2 0.4 0.00019 21.0 0.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 AEO59208.1 - 0.00038 20.1 0.1 0.0006 19.4 0.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 AEO59208.1 - 0.0039 16.9 0.2 0.0071 16.1 0.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 AEO59208.1 - 0.015 14.9 0.1 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AEO59208.1 - 0.044 13.8 0.3 0.081 12.9 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) UPF0547 PF10571.4 AEO59208.1 - 0.61 9.8 3.0 11 5.7 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 FAT PF02259.18 AEO59209.1 - 2.3e-131 437.9 3.1 5.8e-131 436.6 2.1 1.7 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 AEO59209.1 - 1.2e-61 208.2 0.5 3.1e-61 206.8 0.3 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 AEO59209.1 - 2.4e-56 190.0 2.7 4.9e-55 185.8 0.1 4.2 3 1 1 4 4 4 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 AEO59209.1 - 1.2e-42 144.0 1.2 4.9e-42 142.0 0.0 2.8 2 0 0 2 2 2 1 Rapamycin binding domain HEAT PF02985.17 AEO59209.1 - 4.2e-17 60.6 13.1 0.012 15.6 0.0 10.2 10 0 0 10 10 10 5 HEAT repeat HEAT_2 PF13646.1 AEO59209.1 - 1.4e-16 60.4 6.7 0.00075 19.7 0.0 7.6 5 2 1 7 7 7 3 HEAT repeats FATC PF02260.15 AEO59209.1 - 8.7e-16 57.0 0.1 2.8e-15 55.4 0.1 2.0 1 0 0 1 1 1 1 FATC domain HEAT_EZ PF13513.1 AEO59209.1 - 8.7e-11 41.9 10.5 0.01 16.3 0.1 11.3 8 3 3 11 11 11 2 HEAT-like repeat Adaptin_N PF01602.15 AEO59209.1 - 1.5e-08 33.4 4.5 0.0033 15.8 0.2 4.0 1 1 1 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.2 AEO59209.1 - 0.00028 20.7 6.4 0.055 13.3 0.1 6.2 5 1 2 7 7 7 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 AEO59209.1 - 0.012 15.9 6.4 1.8e+02 2.5 0.0 7.4 5 2 3 9 9 9 0 Vacuolar 14 Fab1-binding region 4HBT_2 PF13279.1 AEO59211.1 - 1.2e-06 28.9 0.0 1.6e-06 28.5 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 AEO59211.1 - 7.9e-05 22.7 0.0 0.0001 22.3 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.12 AEO59211.1 - 9.5e-05 21.4 0.2 9.6e-05 21.4 0.1 1.2 1 0 0 1 1 1 1 Acyl-ACP thioesterase PseudoU_synth_2 PF00849.17 AEO59213.1 - 1.2e-28 100.0 0.0 2.2e-28 99.1 0.0 1.5 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.20 AEO59213.1 - 0.0012 18.1 0.0 0.0025 17.1 0.0 1.5 1 0 0 1 1 1 1 S4 domain Ub-Mut7C PF14451.1 AEO59213.1 - 0.015 14.7 0.0 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 Mut7-C ubiquitin LUC7 PF03194.10 AEO59214.1 - 0.00035 20.1 0.0 0.00035 20.1 0.0 1.1 1 0 0 1 1 1 1 LUC7 N_terminus DUF2937 PF11157.3 AEO59214.1 - 0.0083 15.4 1.8 0.011 15.0 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2937) bZIP_1 PF00170.16 AEO59214.1 - 0.054 13.4 15.3 0.17 11.8 10.6 1.8 1 1 0 1 1 1 0 bZIP transcription factor DUF3435 PF11917.3 AEO59214.1 - 0.19 10.4 6.4 0.25 10.0 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) DUF4570 PF15134.1 AEO59214.1 - 1.9 8.3 11.1 5.5 6.8 7.6 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4570) DUF904 PF06005.7 AEO59214.1 - 3.8 7.8 11.9 0.28 11.5 1.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF904) IncA PF04156.9 AEO59214.1 - 4 6.9 5.8 5.5 6.5 4.0 1.2 1 0 0 1 1 1 0 IncA protein bZIP_2 PF07716.10 AEO59214.1 - 9.8 6.0 18.8 4.3e+02 0.8 13.0 2.2 1 1 0 1 1 1 0 Basic region leucine zipper MFS_1 PF07690.11 AEO59216.1 - 3.1e-25 88.6 36.0 1.6e-19 69.8 14.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 AEO59216.1 - 0.032 12.3 3.6 1.4 6.9 0.0 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector Ureidogly_hydro PF04115.7 AEO59217.1 - 2.5e-51 173.2 0.0 3.2e-51 172.9 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate hydrolase SNF2_N PF00176.18 AEO59218.1 - 2e-15 56.3 0.0 3.6e-14 52.2 0.0 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain DNA_methylase PF00145.12 AEO59218.1 - 5.9e-10 38.7 0.0 1.7e-07 30.7 0.0 2.7 2 1 0 2 2 2 2 C-5 cytosine-specific DNA methylase RasGAP PF00616.14 AEO59220.1 - 3.1e-47 160.7 0.0 2.8e-46 157.6 0.0 2.2 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 AEO59220.1 - 0.093 12.5 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 C2 domain Pro_isomerase PF00160.16 AEO59221.1 - 4.3e-47 160.1 0.2 6.2e-47 159.6 0.1 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 AEO59221.1 - 2.9e-12 46.0 10.8 3.3e-07 29.8 0.7 2.4 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 AEO59221.1 - 6.6e-07 28.7 7.9 2.5e-05 23.8 0.3 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 AEO59221.1 - 3.4e-05 23.2 4.6 0.00015 21.2 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 AEO59221.1 - 7.9e-05 22.5 2.9 0.00053 19.8 0.6 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 AEO59221.1 - 0.00059 20.2 1.5 0.00059 20.2 1.1 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 AEO59221.1 - 0.0032 17.1 1.6 0.0088 15.7 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 AEO59221.1 - 0.012 16.0 3.2 0.036 14.5 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 AEO59221.1 - 0.013 15.3 2.0 0.024 14.4 1.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 AEO59221.1 - 0.17 12.6 14.0 0.077 13.7 2.3 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Tyr_Deacylase PF02580.11 AEO59222.1 - 1.4e-46 158.0 0.1 1.6e-46 157.8 0.1 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Not3 PF04065.10 AEO59223.1 - 2.3e-53 180.8 7.2 2.3e-53 180.8 5.0 1.8 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 AEO59223.1 - 2.7e-36 124.3 11.8 3.1e-36 124.2 7.1 1.8 1 1 1 2 2 2 1 NOT2 / NOT3 / NOT5 family DUF2373 PF10180.4 AEO59223.1 - 0.0033 16.9 2.6 0.0063 16.0 1.8 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) DUF1192 PF06698.6 AEO59223.1 - 0.02 14.6 3.6 0.023 14.5 1.2 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) Snapin_Pallidin PF14712.1 AEO59223.1 - 0.061 13.6 0.1 0.14 12.4 0.1 1.5 1 0 0 1 1 1 0 Snapin/Pallidin Seryl_tRNA_N PF02403.17 AEO59223.1 - 2.2 8.3 6.2 6.7 6.7 3.4 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain zf-C2H2 PF00096.21 AEO59225.1 - 6.8 7.2 23.6 0.23 11.8 0.4 4.8 4 0 0 4 4 4 0 Zinc finger, C2H2 type Iso_dh PF00180.15 AEO59226.1 - 1.8e-69 234.3 0.0 2.1e-69 234.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Ino80_Iec3 PF14612.1 AEO59227.1 - 1e-65 222.0 2.5 4.2e-34 118.6 0.3 2.1 1 1 1 2 2 2 2 IEC3 subunit of the Ino80 complex, chromatin re-modelling UPF0160 PF03690.8 AEO59228.1 - 2.3e-125 418.2 0.0 2.6e-125 418.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Endosulfine PF04667.12 AEO59229.1 - 1.3e-20 73.0 0.4 3.1e-20 71.9 0.0 1.7 2 1 0 2 2 2 1 cAMP-regulated phosphoprotein/endosulfine conserved region DUF1793 PF08760.6 AEO59230.1 - 2.3e-63 213.1 0.2 4e-63 212.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Atg31 PF09795.4 AEO59230.1 - 0.11 12.2 0.0 0.33 10.6 0.0 1.8 2 0 0 2 2 2 0 Autophagy-related protein 31 PGAP1 PF07819.8 AEO59231.1 - 4e-10 39.6 0.3 7.7e-10 38.7 0.2 1.5 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 AEO59231.1 - 3.5e-09 36.8 0.0 5.1e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 AEO59231.1 - 1.8e-07 30.6 0.1 4.1e-07 29.5 0.1 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.10 AEO59231.1 - 3.3e-06 26.3 0.0 4.2e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_5 PF12695.2 AEO59231.1 - 0.00014 21.6 0.0 0.00021 21.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 AEO59231.1 - 0.0046 16.0 0.0 0.035 13.2 0.0 2.3 3 0 0 3 3 3 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_1 PF00561.15 AEO59231.1 - 0.0053 16.3 0.0 0.0074 15.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_2 PF01674.13 AEO59231.1 - 0.0058 15.9 0.0 0.043 13.1 0.1 2.3 2 1 0 2 2 2 1 Lipase (class 2) Ser_hydrolase PF06821.8 AEO59231.1 - 0.023 14.2 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase DUF900 PF05990.7 AEO59231.1 - 0.035 13.4 0.0 0.053 12.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Thioesterase PF00975.15 AEO59231.1 - 0.049 13.8 0.0 0.079 13.1 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain RTA1 PF04479.8 AEO59232.1 - 2.8e-14 53.1 9.4 2.8e-14 53.1 6.5 1.4 2 0 0 2 2 2 1 RTA1 like protein CASP_C PF08172.7 AEO59233.1 - 0.031 13.3 0.3 0.068 12.1 0.2 1.5 1 0 0 1 1 1 0 CASP C terminal HSBP1 PF06825.7 AEO59233.1 - 0.049 13.2 1.5 0.089 12.3 1.0 1.3 1 0 0 1 1 1 0 Heat shock factor binding protein 1 GHMP_kinases_C PF08544.8 AEO59233.1 - 0.1 12.7 0.1 0.21 11.8 0.1 1.5 1 0 0 1 1 1 0 GHMP kinases C terminal NAD_binding_6 PF08030.7 AEO59234.1 - 3.3e-20 72.5 0.0 4.9e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 AEO59234.1 - 7.6e-12 45.0 0.0 1.4e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 AEO59234.1 - 0.00012 22.6 0.0 0.058 13.9 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain Ferric_reduct PF01794.14 AEO59234.1 - 0.01 15.9 8.4 0.02 14.9 5.8 1.5 1 0 0 1 1 1 0 Ferric reductase like transmembrane component SEEEED PF14797.1 AEO59234.1 - 0.14 12.2 11.6 0.2 11.7 8.1 1.1 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex zf-C3HC4_2 PF13923.1 AEO59236.1 - 2.8e-08 33.6 8.3 4.8e-08 32.8 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AEO59236.1 - 1.5e-07 30.9 5.4 2.5e-07 30.2 3.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AEO59236.1 - 2e-07 30.7 6.6 3.4e-07 29.9 4.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 AEO59236.1 - 3e-07 29.9 7.0 5.2e-07 29.2 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO59236.1 - 1.8e-06 27.5 5.2 3.1e-06 26.7 3.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 AEO59236.1 - 6.6e-05 22.6 7.1 0.0004 20.1 4.9 2.1 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 AEO59236.1 - 0.0017 18.0 6.5 0.0041 16.8 4.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger TerY-C PF15616.1 AEO59236.1 - 0.21 11.5 2.8 0.86 9.5 1.9 1.9 1 1 0 1 1 1 0 TerY-C metal binding domain zf-MIZ PF02891.15 AEO59236.1 - 0.85 9.1 8.9 3.2 7.3 6.2 2.0 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger FYVE PF01363.16 AEO59236.1 - 0.86 9.5 3.4 2.3 8.1 2.4 1.7 1 1 0 1 1 1 0 FYVE zinc finger zf-rbx1 PF12678.2 AEO59236.1 - 1.1 9.4 4.9 3.3 7.8 3.4 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger Neuregulin PF02158.10 AEO59237.1 - 0.11 11.2 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Neuregulin family CFEM PF05730.6 AEO59238.1 - 4.3 7.2 10.6 11 5.8 7.2 2.0 1 1 0 1 1 1 0 CFEM domain DUF4588 PF15251.1 AEO59239.1 - 5.9e-06 26.4 5.1 2.5e-05 24.3 3.5 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) SNF2_N PF00176.18 AEO59240.1 - 7.7e-83 277.7 0.2 1.3e-82 277.0 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 AEO59240.1 - 1.2e-45 153.9 3.5 4.5e-45 152.1 2.4 2.1 1 0 0 1 1 1 1 SLIDE HAND PF09110.6 AEO59240.1 - 5.3e-37 126.6 4.5 5.3e-37 126.6 3.1 3.9 3 0 0 3 3 3 1 HAND Helicase_C PF00271.26 AEO59240.1 - 2e-15 56.3 0.0 7.2e-15 54.6 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AEO59240.1 - 2.2e-08 34.1 0.0 1.2e-07 31.7 0.0 2.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 AEO59240.1 - 1.6e-05 24.4 0.0 4e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.10 AEO59240.1 - 0.022 14.1 0.1 0.052 12.9 0.1 1.6 1 0 0 1 1 1 0 DEAD_2 AAA_14 PF13173.1 AEO59240.1 - 0.037 13.9 0.1 0.12 12.3 0.1 1.9 1 0 0 1 1 1 0 AAA domain WD40 PF00400.27 AEO59241.1 - 7e-33 111.3 1.3 6.8e-12 44.7 0.1 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 AEO59241.1 - 3.5e-05 22.1 0.1 4.7e-05 21.7 0.1 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 AEO59241.1 - 0.0001 21.1 0.1 0.0047 15.7 0.0 2.5 1 1 2 3 3 3 1 Nup133 N terminal like Coatomer_WDAD PF04053.9 AEO59241.1 - 0.00037 19.4 0.1 0.14 10.9 0.0 2.5 1 1 1 2 2 2 2 Coatomer WD associated region eIF2A PF08662.6 AEO59241.1 - 0.00054 19.7 0.1 1.1 8.9 0.0 3.4 1 1 4 5 5 5 2 Eukaryotic translation initiation factor eIF2A FTHFS PF01268.14 AEO59242.1 - 1.4e-258 858.4 0.3 2e-258 857.9 0.2 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 AEO59242.1 - 6.5e-68 226.8 3.0 7.2e-68 226.7 0.5 2.2 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 AEO59242.1 - 1.8e-39 134.3 0.4 4.3e-39 133.1 0.3 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Prefoldin PF02996.12 AEO59242.1 - 0.18 11.4 0.3 2 8.0 0.0 2.3 2 0 0 2 2 2 0 Prefoldin subunit Fungal_trans PF04082.13 AEO59243.1 - 1.2e-08 34.2 0.0 0.00019 20.4 0.0 2.5 2 0 0 2 2 2 2 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 AEO59243.1 - 6.6e-05 22.9 10.6 0.0013 18.9 1.8 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 AEO59243.1 - 0.00016 21.8 10.6 0.00078 19.6 1.5 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type PH_4 PF15404.1 AEO59243.1 - 6.1 6.3 9.2 0.68 9.4 1.2 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain CTP_transf_2 PF01467.21 AEO59245.1 - 1.6e-22 80.2 0.0 2.6e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase RBD-FIP PF09457.5 AEO59245.1 - 0.26 11.1 0.7 0.86 9.4 0.5 1.9 1 0 0 1 1 1 0 FIP domain F-box-like PF12937.2 AEO59246.1 - 0.021 14.5 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 F-box-like Tctex-1 PF03645.8 AEO59247.1 - 4.7e-35 119.5 0.1 5.5e-35 119.2 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family DUF202 PF02656.10 AEO59248.1 - 1e-13 51.2 4.7 2.1e-13 50.2 2.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2615 PF11027.3 AEO59248.1 - 1.3 9.0 3.0 4.3 7.3 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) 7TMR-DISM_7TM PF07695.6 AEO59248.1 - 2.5 7.7 9.7 8.7 5.9 6.7 1.7 1 1 0 1 1 1 0 7TM diverse intracellular signalling DUF4131 PF13567.1 AEO59248.1 - 4 6.8 6.1 3.5 7.0 3.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Alba PF01918.16 AEO59249.1 - 2e-08 33.7 0.0 3.1e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Alba Nop14 PF04147.7 AEO59250.1 - 0.72 7.7 3.9 1 7.2 2.7 1.1 1 0 0 1 1 1 0 Nop14-like family Plus-3 PF03126.13 AEO59251.1 - 5.8e-35 119.6 0.1 1.5e-34 118.3 0.0 1.8 2 0 0 2 2 2 1 Plus-3 domain COQ7 PF03232.8 AEO59252.1 - 2.1e-63 212.8 0.0 2.6e-63 212.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 AEO59252.1 - 0.0011 19.3 0.0 0.0021 18.3 0.0 1.6 1 1 0 1 1 1 1 Rubrerythrin DUF605 PF04652.11 AEO59252.1 - 0.022 14.1 7.0 0.025 13.9 4.9 1.1 1 0 0 1 1 1 0 Vta1 like Inhibitor_I71 PF12628.2 AEO59252.1 - 0.035 13.7 0.8 0.051 13.2 0.5 1.2 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor Menin PF05053.8 AEO59252.1 - 0.2 9.7 2.8 0.26 9.4 1.9 1.2 1 0 0 1 1 1 0 Menin PLDc PF00614.17 AEO59253.1 - 8.2e-17 60.4 1.1 2.6e-08 33.4 0.2 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 AEO59253.1 - 2e-12 46.9 0.1 6.4e-08 32.3 0.0 3.1 3 1 0 3 3 3 2 PLD-like domain PX PF00787.19 AEO59253.1 - 1.7e-07 31.0 0.0 3e-06 27.0 0.0 2.9 1 1 0 1 1 1 1 PX domain Tubulin PF00091.20 AEO59254.1 - 6.4e-74 248.4 0.0 8.8e-74 247.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 AEO59254.1 - 6.7e-46 155.4 0.2 1.3e-45 154.4 0.0 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 AEO59254.1 - 5e-08 33.0 0.0 1.1e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 AEO59254.1 - 0.071 12.5 0.0 0.21 11.0 0.0 1.8 1 0 0 1 1 1 0 Tubulin domain Oxidored_q6 PF01058.17 AEO59255.1 - 3.8e-22 78.2 0.0 5.4e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Mpp10 PF04006.7 AEO59256.1 - 1.7e-92 310.7 77.4 1.5e-88 297.7 53.6 2.3 1 1 0 1 1 1 1 Mpp10 protein DUF445 PF04286.7 AEO59256.1 - 0.011 15.2 2.6 1.7 8.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF445) IL3 PF02059.10 AEO59256.1 - 0.16 12.0 0.9 1.1 9.3 0.1 2.3 2 0 0 2 2 2 0 Interleukin-3 SPX PF03105.14 AEO59257.1 - 4.3e-06 26.7 0.1 2.6e-05 24.1 0.0 2.0 1 1 1 2 2 2 1 SPX domain TcdA_TcdB PF12919.2 AEO59257.1 - 0.063 11.7 0.0 0.063 11.7 0.0 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain CcmD PF04995.9 AEO59257.1 - 0.076 12.7 2.6 1.1 9.0 0.1 2.9 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Amidohydro_3 PF07969.6 AEO59260.1 - 1.8e-49 169.0 0.4 2.3e-49 168.7 0.3 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.15 AEO59260.1 - 0.012 15.3 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase family HECT PF00632.20 AEO59261.1 - 2.9e-92 309.1 0.0 4.7e-92 308.5 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 AEO59261.1 - 1.7e-33 114.0 21.9 1.7e-11 43.7 4.6 3.9 3 0 0 3 3 3 3 WW domain C2 PF00168.25 AEO59261.1 - 8.3e-18 64.0 0.1 2.4e-17 62.5 0.1 1.8 1 0 0 1 1 1 1 C2 domain RRM_1 PF00076.17 AEO59262.1 - 8.1e-17 60.6 0.0 1.4e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO59262.1 - 8.7e-17 60.8 0.3 1.9e-16 59.8 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO59262.1 - 2e-07 30.7 0.0 3.3e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GRP PF07172.6 AEO59262.1 - 0.013 15.9 12.2 0.036 14.5 8.4 1.7 1 0 0 1 1 1 0 Glycine rich protein family V_ATPase_I PF01496.14 AEO59262.1 - 0.19 9.5 0.2 0.21 9.4 0.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family WD40 PF00400.27 AEO59263.1 - 1.6e-48 160.8 27.5 1.9e-08 33.8 0.2 10.2 11 0 0 11 11 11 9 WD domain, G-beta repeat Nup160 PF11715.3 AEO59263.1 - 0.00035 18.8 1.4 0.0068 14.5 0.0 2.9 3 0 0 3 3 3 1 Nucleoporin Nup120/160 PD40 PF07676.7 AEO59263.1 - 0.024 14.2 0.2 26 4.6 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Glyco_tran_28_C PF04101.11 AEO59264.1 - 5.1e-16 58.7 1.6 1.5e-15 57.2 0.0 2.3 2 1 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain MRP-S28 PF10213.4 AEO59265.1 - 9.3e-49 164.7 0.5 1.8e-48 163.8 0.1 1.7 2 0 0 2 2 2 1 Mitochondrial ribosomal subunit protein Aldedh PF00171.17 AEO59266.1 - 5.9e-80 268.8 0.0 7e-80 268.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ECR1_N PF14382.1 AEO59267.1 - 8.6e-13 47.3 0.2 1.8e-12 46.2 0.2 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 AEO59267.1 - 0.0028 17.5 0.1 0.019 14.9 0.0 2.2 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 S1 PF00575.18 AEO59267.1 - 0.058 13.4 5.6 1.3 9.1 0.0 3.9 6 0 0 6 6 6 0 S1 RNA binding domain Acyl_transf_1 PF00698.16 AEO59268.1 - 5.5e-16 58.7 0.2 2.6e-09 36.8 0.1 2.1 2 0 0 2 2 2 2 Acyl transferase domain DUF2458 PF10454.4 AEO59268.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) Sedlin_N PF04628.8 AEO59269.1 - 1.4e-18 67.0 0.0 1.6e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Glyco_transf_90 PF05686.7 AEO59270.1 - 8.2e-23 80.7 0.0 1.6e-20 73.1 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 90 AFG1_ATPase PF03969.11 AEO59271.1 - 8.9e-53 179.3 0.1 3.7e-25 88.5 0.0 5.0 3 2 1 5 5 5 4 AFG1-like ATPase AAA_5 PF07728.9 AEO59271.1 - 0.00032 20.4 0.0 0.0006 19.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 AEO59271.1 - 0.0032 17.4 0.3 0.041 13.8 0.2 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 AEO59271.1 - 0.012 15.7 0.0 0.036 14.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain DUF4149 PF13664.1 AEO59271.1 - 0.023 14.7 0.1 0.045 13.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) AAA PF00004.24 AEO59271.1 - 0.033 14.3 0.0 0.062 13.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 AEO59271.1 - 0.044 13.4 0.0 0.085 12.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.1 AEO59271.1 - 0.11 11.9 0.0 0.42 10.1 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain KAP_NTPase PF07693.9 AEO59271.1 - 0.15 11.0 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain PIF1 PF05970.9 AEO59271.1 - 0.25 10.2 0.0 0.4 9.5 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase Nucleoporin_C PF03177.9 AEO59272.1 - 6.1e-109 365.1 13.1 8.6e-109 364.6 9.1 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 AEO59272.1 - 1.5e-96 323.7 0.0 2.1e-96 323.2 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Pkinase PF00069.20 AEO59273.1 - 1.6e-36 125.7 0.0 2.4e-36 125.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO59273.1 - 3.5e-14 52.5 0.0 4.8e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AEO59273.1 - 0.014 15.1 0.0 0.48 10.1 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF605 PF04652.11 AEO59273.1 - 1.1 8.5 12.4 1.4 8.2 8.6 1.2 1 0 0 1 1 1 0 Vta1 like EMP24_GP25L PF01105.19 AEO59274.1 - 8e-52 175.6 0.0 9e-52 175.4 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Metallophos_2 PF12850.2 AEO59276.1 - 1.2e-05 25.2 0.0 1.3e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 AEO59276.1 - 7e-05 22.3 0.2 0.00014 21.3 0.1 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Hexapep PF00132.19 AEO59277.1 - 1.5e-13 49.5 20.8 1.6e-10 39.9 1.7 3.5 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 AEO59277.1 - 4.6e-13 48.4 19.5 4.5e-09 35.7 0.9 2.8 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.3 AEO59277.1 - 2.9e-12 46.4 0.0 5.9e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Maltose acetyltransferase Zn_clus PF00172.13 AEO59277.1 - 1.1e-08 34.8 9.7 2.3e-08 33.8 6.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Adap_comp_sub PF00928.16 AEO59278.1 - 4.5e-62 209.5 0.0 5e-61 206.0 0.0 2.0 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 AEO59278.1 - 6.3e-05 22.7 0.0 9.3e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF4536 PF15055.1 AEO59279.1 - 4.3e-05 23.4 1.7 6.1e-05 23.0 1.2 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4536) NAD_binding_8 PF13450.1 AEO59279.1 - 0.033 14.1 0.6 0.046 13.7 0.4 1.3 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Glyco_hydro_6 PF01341.12 AEO59280.1 - 2.6e-102 342.3 1.2 3.2e-102 341.9 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Glyco_hydro_71 PF03659.9 AEO59280.1 - 0.027 12.9 0.1 0.038 12.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 71 RVT_1 PF00078.22 AEO59281.1 - 0.034 13.5 0.2 0.036 13.4 0.1 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) FtsJ PF01728.14 AEO59284.1 - 7.3e-64 215.0 0.0 9.8e-64 214.6 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 AEO59284.1 - 2.7e-05 23.9 0.0 6.6e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO59284.1 - 0.00097 19.6 0.0 0.0084 16.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO59284.1 - 0.028 14.0 0.0 2.7 7.5 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Snapin_Pallidin PF14712.1 AEO59285.1 - 0.002 18.4 11.2 0.002 18.4 7.8 5.3 2 1 3 5 5 5 3 Snapin/Pallidin OST3_OST6 PF04756.8 AEO59286.1 - 2.8e-19 69.2 0.6 4.5e-19 68.5 0.4 1.3 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 AEO59286.1 - 0.044 13.4 0.0 0.069 12.8 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Abi PF02517.11 AEO59286.1 - 0.94 9.6 4.4 1.9 8.6 3.0 1.8 1 1 0 1 1 1 0 CAAX protease self-immunity Mito_carr PF00153.22 AEO59287.1 - 3.6e-75 247.7 2.7 2.8e-25 87.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.17 AEO59288.1 - 6e-12 45.0 0.0 8.1e-12 44.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO59288.1 - 8.2e-08 32.1 0.0 1.3e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO59288.1 - 1.1e-07 31.5 0.0 1.5e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 AEO59288.1 - 0.00035 20.2 0.0 0.00052 19.7 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif MIP-T3 PF10243.4 AEO59288.1 - 9.4 4.5 18.2 12 4.2 12.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 MBOAT PF03062.14 AEO59289.1 - 3.2e-36 125.0 22.8 3.2e-36 125.0 15.8 1.6 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 AEO59289.1 - 1.5e-06 28.1 4.4 3e-06 27.2 3.1 1.5 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family tRNA-synt_1b PF00579.20 AEO59290.1 - 2.6e-57 194.1 0.0 3.4e-57 193.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) CH PF00307.26 AEO59291.1 - 4.6e-59 197.1 0.0 9.7e-16 57.7 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.1 AEO59291.1 - 2.7e-06 27.4 0.2 7.7e-05 22.7 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 AEO59291.1 - 0.0025 16.9 1.1 0.35 10.2 0.1 3.4 3 0 0 3 3 3 1 EF hand CAMSAP_CH PF11971.3 AEO59291.1 - 0.0064 16.1 0.0 35 4.1 0.0 3.5 3 0 0 3 3 3 0 CAMSAP CH domain EF-hand_6 PF13405.1 AEO59291.1 - 0.0094 15.7 0.6 0.16 11.9 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain Ank_2 PF12796.2 AEO59292.1 - 0.014 15.7 0.0 0.028 14.7 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_3 PF13606.1 AEO59292.1 - 0.14 12.4 0.0 0.53 10.6 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeat zf-RING_2 PF13639.1 AEO59292.1 - 0.15 11.8 9.8 0.45 10.3 6.8 1.8 1 1 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.1 AEO59292.1 - 0.19 11.4 2.8 0.38 10.5 2.0 1.5 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 AEO59292.1 - 1.5 8.9 7.3 0.23 11.5 1.9 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DDHD PF02862.12 AEO59293.1 - 3e-75 252.9 0.1 3e-75 252.9 0.1 3.5 2 2 0 2 2 2 1 DDHD domain Abhydrolase_5 PF12695.2 AEO59293.1 - 0.017 14.9 0.0 0.071 12.8 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF2305 PF10230.4 AEO59293.1 - 0.025 14.0 0.0 0.078 12.3 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) RNA_pol_Rpb1_5 PF04998.12 AEO59294.1 - 1.6e-87 293.2 0.2 2.6e-87 292.6 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 AEO59294.1 - 6.6e-84 282.0 0.3 1.7e-83 280.6 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 AEO59294.1 - 1.9e-67 226.3 0.0 4.3e-67 225.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 AEO59294.1 - 9.2e-37 126.2 0.0 2.7e-36 124.6 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 AEO59294.1 - 8.3e-33 112.3 0.1 3.3e-32 110.4 0.0 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 DUF159 PF02586.9 AEO59295.1 - 1.7e-55 187.7 0.0 2.6e-55 187.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 Sec10 PF07393.6 AEO59297.1 - 0.083 11.0 0.0 0.096 10.8 0.0 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec10 GMC_oxred_N PF00732.14 AEO59298.1 - 3.3e-26 92.1 0.0 1e-25 90.5 0.0 1.9 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 AEO59298.1 - 5.6e-22 78.5 0.2 9.9e-22 77.7 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 AEO59298.1 - 3.3e-09 36.1 0.4 6.5e-06 25.2 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 AEO59298.1 - 1e-08 34.4 0.1 2.6e-05 23.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 AEO59298.1 - 1.5e-05 24.9 0.0 3.9e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 AEO59298.1 - 3.5e-05 23.9 0.0 0.00063 19.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 AEO59298.1 - 3.8e-05 23.6 0.0 6.9e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 AEO59298.1 - 0.00036 19.7 0.1 0.00063 18.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family DOMON PF03351.12 AEO59298.1 - 0.00042 20.2 0.0 0.0012 18.8 0.0 1.8 1 0 0 1 1 1 1 DOMON domain HI0933_like PF03486.9 AEO59298.1 - 0.00053 18.5 0.1 0.00082 17.9 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 AEO59298.1 - 0.00053 19.1 0.0 0.038 13.0 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 AEO59298.1 - 0.0022 18.3 0.0 0.13 12.7 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 AEO59298.1 - 0.017 14.0 0.0 0.032 13.1 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 AEO59298.1 - 0.026 13.5 0.1 0.043 12.8 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.13 AEO59298.1 - 0.042 13.8 0.0 0.081 12.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.11 AEO59298.1 - 0.046 13.1 0.1 0.11 11.9 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.1 AEO59298.1 - 0.079 12.7 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding GIDA PF01134.17 AEO59298.1 - 0.1 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF4419 PF14388.1 AEO59300.1 - 1.2e-57 195.4 0.0 9.3e-49 166.2 0.1 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4419) RVT_1 PF00078.22 AEO59301.1 - 0.039 13.3 0.2 0.04 13.2 0.1 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) TypeIII_RM_meth PF12564.3 AEO59301.1 - 7.9 6.5 8.9 1.5 8.8 0.2 2.9 1 1 0 2 2 2 0 Type III restriction/modification enzyme methylation subunit DUF4431 PF14485.1 AEO59304.1 - 0.059 13.0 0.0 0.09 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4431) AA_permease_2 PF13520.1 AEO59305.1 - 5.2e-60 203.1 36.6 6.4e-60 202.8 25.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 AEO59305.1 - 2.7e-17 62.2 35.2 3.5e-17 61.9 24.4 1.0 1 0 0 1 1 1 1 Amino acid permease Nop14 PF04147.7 AEO59307.1 - 1.5 6.6 13.7 2 6.2 9.5 1.1 1 0 0 1 1 1 0 Nop14-like family zf-C2H2_4 PF13894.1 AEO59309.1 - 1.9e-15 55.9 12.4 3.2e-05 23.9 0.0 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 AEO59309.1 - 3.9e-15 55.1 18.3 2.8e-05 24.2 0.9 3.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 AEO59309.1 - 5.8e-05 23.1 13.1 0.0018 18.4 0.3 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-met PF12874.2 AEO59309.1 - 0.0014 18.7 2.7 0.18 12.0 0.0 3.7 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 AEO59309.1 - 0.0015 18.5 7.0 1.7 8.8 0.1 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 AEO59309.1 - 0.0028 17.4 6.4 1.6 8.7 0.0 3.7 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_2 PF12756.2 AEO59309.1 - 0.13 12.3 5.2 5.5 7.1 0.1 3.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.5 AEO59309.1 - 0.14 12.1 6.0 13 5.8 0.1 3.2 3 0 0 3 3 3 0 Zinc ribbon domain LIM PF00412.17 AEO59309.1 - 0.14 12.2 5.5 0.17 11.9 1.1 2.1 2 0 0 2 2 2 0 LIM domain zf-TRAF PF02176.13 AEO59309.1 - 0.17 12.2 6.0 0.17 12.2 0.8 2.2 2 0 0 2 2 2 0 TRAF-type zinc finger zf-Di19 PF05605.7 AEO59309.1 - 0.17 11.9 2.1 0.19 11.9 0.4 1.9 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Ogr_Delta PF04606.7 AEO59309.1 - 0.57 9.8 5.5 0.3 10.7 0.9 2.3 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger zf-H2C2_5 PF13909.1 AEO59309.1 - 8.1 6.8 9.6 0.76 10.1 0.4 3.2 3 1 0 3 3 3 0 C2H2-type zinc-finger domain MARVEL PF01284.18 AEO59310.1 - 0.58 9.9 3.9 2 8.2 2.7 1.8 1 1 0 1 1 1 0 Membrane-associating domain CAP59_mtransfer PF11735.3 AEO59312.1 - 1.1e-62 211.4 0.0 1.3e-62 211.1 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Yae1_N PF09811.4 AEO59313.1 - 0.014 14.9 3.1 0.025 14.0 2.0 1.6 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Lipoxygenase PF00305.14 AEO59314.1 - 1.4e-55 188.5 0.8 7.3e-54 182.8 0.3 2.0 2 0 0 2 2 2 2 Lipoxygenase DUF900 PF05990.7 AEO59315.1 - 0.0021 17.4 0.1 0.0038 16.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) PE-PPE PF08237.6 AEO59315.1 - 0.019 14.4 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain Lipase_3 PF01764.20 AEO59315.1 - 0.054 13.1 0.1 1.7 8.2 0.0 2.3 2 0 0 2 2 2 0 Lipase (class 3) DUF676 PF05057.9 AEO59315.1 - 0.11 11.7 0.0 0.36 10.0 0.0 1.8 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Glyco_transf_25 PF01755.12 AEO59316.1 - 7.9e-10 38.7 0.0 3.5e-06 26.8 0.0 2.2 2 1 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) GTP_EFTU PF00009.22 AEO59319.1 - 2.7e-46 157.3 0.0 4.2e-46 156.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 AEO59319.1 - 1.7e-38 130.8 6.2 2.9e-38 130.0 4.3 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 AEO59319.1 - 1.8e-18 66.1 0.0 4.3e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 AEO59319.1 - 3.3e-06 26.8 0.0 5.3e-05 22.9 0.0 2.6 2 1 0 2 2 2 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 AEO59319.1 - 0.00013 22.0 0.1 0.00034 20.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 AEO59319.1 - 0.00075 19.4 0.0 0.0019 18.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 AEO59319.1 - 0.00084 18.7 0.0 0.0031 16.9 0.0 1.9 2 0 0 2 2 2 1 Ras family DUF35 PF01796.12 AEO59319.1 - 0.06 13.5 1.2 20 5.5 0.1 3.4 3 0 0 3 3 3 0 DUF35 OB-fold domain SRPRB PF09439.5 AEO59319.1 - 0.089 12.0 0.1 0.57 9.3 0.0 2.3 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit Glyco_hydro_10 PF00331.15 AEO59320.1 - 1.1e-104 349.9 0.1 1.2e-104 349.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 PTase_Orf2 PF11468.3 AEO59320.1 - 0.041 13.0 0.0 0.07 12.3 0.0 1.2 1 0 0 1 1 1 0 Aromatic prenyltransferase Orf2 Cellulase-like PF12876.2 AEO59320.1 - 0.085 13.3 0.0 0.27 11.7 0.0 1.8 1 0 0 1 1 1 0 Sugar-binding cellulase-like DUF1079 PF06435.6 AEO59320.1 - 0.11 12.4 0.8 2.1 8.3 0.1 2.6 2 0 0 2 2 2 0 Repeat of unknown function (DUF1079) Gly_transf_sug PF04488.10 AEO59321.1 - 7.3e-07 29.5 0.0 1.5e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 AEO59321.1 - 0.001 17.6 0.1 0.0015 17.1 0.0 1.1 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain ADH_zinc_N_2 PF13602.1 AEO59322.1 - 2.7e-18 67.0 0.2 4.9e-18 66.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 AEO59322.1 - 1.3e-13 50.5 0.8 2.1e-13 49.9 0.6 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Semialdhyde_dh PF01118.19 AEO59322.1 - 8.9e-05 22.7 0.6 0.00017 21.8 0.4 1.5 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 AEO59322.1 - 0.0046 16.4 0.5 0.0067 15.8 0.4 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ldh_1_N PF00056.18 AEO59322.1 - 0.005 16.6 0.4 0.0076 16.0 0.2 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain ADH_N PF08240.7 AEO59322.1 - 0.011 15.5 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain DapB_N PF01113.15 AEO59322.1 - 0.017 15.0 0.1 0.028 14.3 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Peroxidase_2 PF01328.12 AEO59323.1 - 1.1e-11 43.9 0.0 2.9e-10 39.3 0.0 2.0 1 1 1 2 2 2 2 Peroxidase, family 2 CorA PF01544.13 AEO59324.1 - 1.5e-11 43.8 0.3 4.6e-11 42.2 0.1 1.9 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF4231 PF14015.1 AEO59324.1 - 0.094 12.7 0.1 0.59 10.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) AMP-binding PF00501.23 AEO59325.1 - 0 1305.9 0.0 3.6e-84 282.5 0.0 5.3 5 0 0 5 5 5 5 AMP-binding enzyme Condensation PF00668.15 AEO59325.1 - 9.1e-301 993.3 0.0 3.2e-44 151.0 0.0 11.8 9 3 1 10 10 10 9 Condensation domain PP-binding PF00550.20 AEO59325.1 - 1.2e-75 249.7 0.0 5e-15 55.5 0.0 7.3 7 0 0 7 7 7 6 Phosphopantetheine attachment site AMP-binding_C PF13193.1 AEO59325.1 - 1.4e-21 77.1 11.3 2.5e-05 25.1 0.0 6.3 5 0 0 5 5 5 4 AMP-binding enzyme C-terminal domain HxxPF_rpt PF13745.1 AEO59325.1 - 1.9e-11 44.1 0.1 0.00059 20.0 0.0 6.0 5 0 0 5 5 5 1 HxxPF-repeated domain Transferase PF02458.10 AEO59325.1 - 1.6e-06 26.8 0.0 0.26 9.6 0.0 5.7 7 0 0 7 7 7 1 Transferase family GH3 PF03321.8 AEO59325.1 - 1.9 6.9 0.1 19 3.6 0.0 2.3 2 0 0 2 2 2 0 GH3 auxin-responsive promoter AATase PF07247.7 AEO59325.1 - 6.7 5.1 0.0 87 1.4 0.0 2.8 3 0 0 3 3 3 0 Alcohol acetyltransferase PigN PF04987.9 AEO59325.1 - 6.8 5.2 0.0 12 4.3 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) ABC_tran PF00005.22 AEO59326.1 - 1.6e-45 154.7 0.0 3.6e-23 82.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 AEO59326.1 - 3.5e-16 59.4 22.8 1.4e-09 37.8 6.2 2.9 2 1 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 AEO59326.1 - 8.8e-16 58.7 0.2 0.0026 17.7 0.0 4.3 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 AEO59326.1 - 2.4e-11 43.2 2.3 0.0047 16.1 0.4 3.9 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 AEO59326.1 - 1.3e-08 34.1 0.6 0.0015 18.0 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 AEO59326.1 - 2.4e-08 34.1 0.5 0.0015 18.5 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 AEO59326.1 - 3e-07 31.2 0.2 0.036 14.8 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 AEO59326.1 - 3.9e-07 29.6 0.0 0.037 13.4 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 AEO59326.1 - 5.3e-07 29.8 0.8 0.045 13.8 0.2 3.1 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.1 AEO59326.1 - 2.5e-06 27.4 0.0 0.025 14.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 AEO59326.1 - 2.8e-06 27.2 0.2 0.091 12.7 0.0 3.0 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_10 PF12846.2 AEO59326.1 - 4.3e-06 26.3 3.0 0.038 13.4 0.1 3.4 3 1 1 4 4 3 2 AAA-like domain DUF258 PF03193.11 AEO59326.1 - 1.6e-05 24.1 0.1 0.078 12.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 AEO59326.1 - 1.8e-05 25.1 0.0 0.078 13.4 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein DUF87 PF01935.12 AEO59326.1 - 6.1e-05 22.9 1.3 0.015 15.1 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 Arch_ATPase PF01637.13 AEO59326.1 - 6.6e-05 22.7 0.1 0.043 13.5 0.0 2.8 2 1 0 2 2 2 1 Archaeal ATPase cobW PF02492.14 AEO59326.1 - 0.0001 21.8 0.2 0.14 11.6 0.0 2.6 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 AEO59326.1 - 0.00013 21.4 0.0 0.06 12.8 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family Dynamin_N PF00350.18 AEO59326.1 - 0.00023 20.9 0.6 0.066 13.0 0.0 2.4 2 0 0 2 2 2 1 Dynamin family MobB PF03205.9 AEO59326.1 - 0.00025 20.7 1.0 0.61 9.7 0.1 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 AEO59326.1 - 0.00042 20.0 3.0 1.1 8.9 0.0 3.5 3 0 0 3 3 3 2 NACHT domain AAA_23 PF13476.1 AEO59326.1 - 0.00046 20.5 3.4 0.061 13.6 0.1 2.4 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 AEO59326.1 - 0.00062 20.0 0.0 1.2 9.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 AEO59326.1 - 0.00068 18.6 0.1 0.032 13.1 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein RNA_helicase PF00910.17 AEO59326.1 - 0.0008 19.5 0.0 0.49 10.6 0.0 3.0 3 0 0 3 3 2 1 RNA helicase AAA_19 PF13245.1 AEO59326.1 - 0.0026 17.4 0.2 0.18 11.5 0.0 3.2 3 0 0 3 3 2 1 Part of AAA domain AAA_14 PF13173.1 AEO59326.1 - 0.003 17.4 0.0 3.5 7.5 0.0 2.9 2 1 1 3 3 3 0 AAA domain Zeta_toxin PF06414.7 AEO59326.1 - 0.0035 16.4 0.1 0.35 9.9 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_24 PF13479.1 AEO59326.1 - 0.0042 16.7 0.1 0.15 11.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 AEO59326.1 - 0.0051 16.4 0.0 1.4 8.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF3987 PF13148.1 AEO59326.1 - 0.013 14.1 0.0 0.28 9.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) GTP_EFTU PF00009.22 AEO59326.1 - 0.017 14.5 0.0 0.24 10.7 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 AEO59326.1 - 0.026 14.0 0.3 1.8 8.0 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA PF00004.24 AEO59326.1 - 0.028 14.6 0.3 3 8.0 0.0 3.3 2 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 AEO59326.1 - 0.063 12.1 0.1 5.1 5.8 0.1 3.1 3 1 0 3 3 3 0 NB-ARC domain NTPase_1 PF03266.10 AEO59326.1 - 0.086 12.5 2.2 8.2 6.0 0.0 2.7 3 0 0 3 3 2 0 NTPase KAP_NTPase PF07693.9 AEO59326.1 - 0.087 11.8 0.0 5.5 5.8 0.0 2.6 2 0 0 2 2 2 0 KAP family P-loop domain Adeno_IVa2 PF02456.10 AEO59326.1 - 0.096 11.3 0.1 1.8 7.1 0.0 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_28 PF13521.1 AEO59326.1 - 0.11 12.5 0.1 21 5.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA12 PF10443.4 AEO59326.1 - 0.11 10.9 0.1 1.2 7.5 0.0 2.0 2 0 0 2 2 2 0 RNA12 protein DUF815 PF05673.8 AEO59326.1 - 0.12 11.3 0.1 7.4 5.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) SbcCD_C PF13558.1 AEO59326.1 - 0.12 12.3 0.2 4.9 7.1 0.0 3.0 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Pox_A32 PF04665.7 AEO59326.1 - 0.14 11.3 0.3 9.3 5.4 0.0 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein zf-C2H2_4 PF13894.1 AEO59328.1 - 4.1e-09 36.1 5.7 0.032 14.5 0.3 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 AEO59328.1 - 1.1e-08 34.8 6.0 0.0014 18.8 0.1 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 AEO59328.1 - 7.8e-05 22.7 12.4 0.055 13.7 0.1 4.6 4 1 0 4 4 4 2 Zinc-finger double domain zf-H2C2_5 PF13909.1 AEO59328.1 - 0.00056 19.9 4.0 0.0014 18.7 0.0 3.0 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-Di19 PF05605.7 AEO59328.1 - 0.09 12.9 0.6 0.09 12.9 0.4 3.0 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.6 AEO59328.1 - 0.093 12.3 6.0 8.8 6.0 0.0 3.5 3 0 0 3 3 3 0 GAGA factor MFS_1 PF07690.11 AEO59330.1 - 1.5e-33 115.9 27.6 2.2e-33 115.4 19.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1049 PF06305.6 AEO59330.1 - 0.88 9.0 7.0 4.2 6.9 0.0 4.1 4 1 0 4 4 4 0 Protein of unknown function (DUF1049) Glyco_hydro_88 PF07470.8 AEO59331.1 - 2.4e-75 253.6 0.2 6.2e-75 252.3 0.1 1.6 1 1 0 1 1 1 1 Glycosyl Hydrolase Family 88 DUF1680 PF07944.7 AEO59331.1 - 0.0016 16.8 0.5 0.0022 16.3 0.4 1.1 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) Chorismate_bind PF00425.13 AEO59332.1 - 1.6e-81 273.4 0.0 3.8e-79 265.6 0.0 3.0 2 1 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 AEO59332.1 - 3.2e-32 111.4 0.0 4.8e-28 97.9 0.0 3.3 3 0 0 3 3 3 2 Anthranilate synthase component I, N terminal region Methyltransf_11 PF08241.7 AEO59333.1 - 5.6e-19 68.4 0.0 8.6e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO59333.1 - 4e-13 49.9 0.1 6.9e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO59333.1 - 5.2e-11 42.7 0.0 8.1e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO59333.1 - 7.2e-09 35.6 0.5 2e-08 34.2 0.3 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO59333.1 - 2.2e-08 33.9 0.0 3.5e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO59333.1 - 3.7e-08 33.7 0.0 1.1e-07 32.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO59333.1 - 1.4e-07 31.2 0.0 2.4e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AEO59333.1 - 2.8e-05 23.3 0.0 3.9e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 AEO59333.1 - 0.00054 19.3 0.0 0.00084 18.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.7 AEO59333.1 - 0.0015 17.4 0.0 0.0022 16.9 0.0 1.1 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_32 PF13679.1 AEO59333.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 AEO59333.1 - 0.21 10.5 0.0 0.31 10.0 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Pectate_lyase PF03211.8 AEO59334.1 - 5.4e-81 271.1 5.9 6.7e-81 270.7 4.1 1.0 1 0 0 1 1 1 1 Pectate lyase Uso1_p115_C PF04871.8 AEO59335.1 - 0.062 13.2 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF3628 PF12300.3 AEO59335.1 - 1.6 8.7 10.7 1.5 8.8 6.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3628) COesterase PF00135.23 AEO59337.1 - 6.2e-100 335.4 0.0 1.6e-90 304.3 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 AEO59337.1 - 1.4e-11 44.3 0.6 2.1e-11 43.7 0.4 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AEO59337.1 - 0.00042 20.1 0.2 0.00071 19.3 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 AEO59337.1 - 0.16 11.1 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family NAD_binding_2 PF03446.10 AEO59338.1 - 5.5e-15 55.5 0.1 8.4e-15 54.9 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 AEO59338.1 - 5e-07 30.0 0.1 1.1e-06 28.9 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 AEO59338.1 - 0.00038 20.5 0.0 0.0007 19.7 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 AEO59338.1 - 0.0018 17.7 0.1 0.0038 16.6 0.1 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 AEO59338.1 - 0.0035 17.0 0.6 0.022 14.5 0.4 2.0 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TMEM154 PF15102.1 AEO59338.1 - 0.043 13.5 0.0 0.067 12.8 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family PELOTA_1 PF15608.1 AEO59339.1 - 0.035 13.8 0.0 0.041 13.6 0.0 1.1 1 0 0 1 1 1 0 PELOTA RNA binding domain DUF4044 PF13253.1 AEO59339.1 - 0.21 10.7 1.4 0.37 9.9 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) APH PF01636.18 AEO59340.1 - 6e-07 29.4 0.0 8.3e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 AEO59340.1 - 2.4e-05 24.0 0.0 3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 AEO59340.1 - 0.0057 15.8 0.0 0.029 13.5 0.0 1.9 2 0 0 2 2 2 1 Ecdysteroid kinase Cu_bind_like PF02298.12 AEO59341.1 - 0.068 12.9 0.1 1.2 8.9 0.0 2.1 2 0 0 2 2 2 0 Plastocyanin-like domain RNA_pol_Rpb2_6 PF00562.23 AEO59342.1 - 8.2e-126 419.8 0.0 1.5e-125 419.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 AEO59342.1 - 3.5e-53 179.5 0.0 6.1e-53 178.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 AEO59342.1 - 6e-46 156.2 0.0 1.1e-45 155.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 AEO59342.1 - 1e-30 105.8 0.1 2.4e-30 104.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 AEO59342.1 - 2.3e-24 85.0 0.1 7.4e-24 83.4 0.1 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_3 PF04565.11 AEO59342.1 - 6.7e-23 80.2 0.0 1.9e-22 78.7 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.8 AEO59342.1 - 6.5e-20 70.7 0.2 1.9e-19 69.2 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 V-ATPase_G PF03179.10 AEO59344.1 - 7.3e-32 109.7 20.5 8.2e-32 109.6 14.2 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit YusW PF14039.1 AEO59344.1 - 0.0035 17.5 5.6 0.0056 16.9 3.9 1.3 1 0 0 1 1 1 1 YusW-like protein DUF2203 PF09969.4 AEO59344.1 - 0.064 13.4 6.1 0.085 13.0 4.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Asp-B-Hydro_N PF05279.6 AEO59344.1 - 0.066 13.0 11.1 0.076 12.8 7.7 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region ATP-synt_B PF00430.13 AEO59344.1 - 0.28 11.0 24.0 0.15 11.8 7.8 2.1 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) EspA PF03433.8 AEO59344.1 - 0.34 10.3 4.0 0.32 10.4 2.3 1.3 1 1 0 1 1 1 0 EspA-like secreted protein DAG_kinase_N PF14513.1 AEO59344.1 - 0.35 11.0 2.7 0.52 10.4 0.2 1.9 1 1 1 2 2 2 0 Diacylglycerol kinase N-terminus DUF87 PF01935.12 AEO59344.1 - 0.46 10.2 3.2 0.51 10.1 2.2 1.0 1 0 0 1 1 1 0 Domain of unknown function DUF87 DUF2201_N PF13203.1 AEO59344.1 - 0.59 9.2 5.8 0.65 9.1 4.0 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF3552 PF12072.3 AEO59344.1 - 0.66 9.1 23.9 0.087 12.0 8.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) Atg14 PF10186.4 AEO59344.1 - 0.67 8.8 10.2 0.77 8.6 7.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Nop25 PF09805.4 AEO59344.1 - 0.82 9.7 16.5 1.1 9.3 11.4 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Vfa1 PF08432.5 AEO59344.1 - 0.98 9.4 13.4 1.1 9.2 9.3 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 ATP11 PF06644.6 AEO59344.1 - 3.8 6.9 10.5 4.6 6.6 7.3 1.0 1 0 0 1 1 1 0 ATP11 protein AAA_11 PF13086.1 AEO59344.1 - 4.2 6.8 6.9 5.2 6.5 4.8 1.2 1 0 0 1 1 1 0 AAA domain Ribosomal_L6e PF01159.14 AEO59344.1 - 4.4 7.5 9.5 2 8.6 4.8 1.6 1 1 1 2 2 2 0 Ribosomal protein L6e OmpH PF03938.9 AEO59344.1 - 4.6 7.1 16.1 5.7 6.8 11.2 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) HSP70 PF00012.15 AEO59344.1 - 4.6 5.0 11.1 5.1 4.8 7.7 1.0 1 0 0 1 1 1 0 Hsp70 protein SAPS PF04499.10 AEO59344.1 - 6.4 5.2 7.2 6.6 5.2 5.0 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF3987 PF13148.1 AEO59344.1 - 7.5 4.9 14.3 8.7 4.7 9.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Potyvirid-P3 PF13608.1 AEO59344.1 - 8.9 5.3 8.1 10 5.0 5.6 1.0 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein CTNNBL PF08216.6 AEO59345.1 - 5.4e-34 116.0 0.0 1.7e-32 111.1 0.0 2.8 3 0 0 3 3 3 1 Catenin-beta-like, Arm-motif containing nuclear SUA5 PF03481.8 AEO59345.1 - 0.0015 18.6 0.5 0.0051 16.8 0.1 2.0 2 0 0 2 2 2 1 Putative GTP-binding controlling metal-binding Arm PF00514.18 AEO59345.1 - 0.015 15.1 1.2 0.24 11.3 0.0 3.2 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 AEO59345.1 - 0.08 13.2 9.9 0.1 12.9 0.3 3.7 4 0 0 4 4 4 0 HEAT repeats His_Phos_1 PF00300.17 AEO59346.1 - 3.4e-19 69.4 0.0 4.7e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF4149 PF13664.1 AEO59347.1 - 1.7e-20 72.9 3.8 3.3e-20 72.0 2.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4149) DUF1996 PF09362.5 AEO59348.1 - 1e-86 290.4 0.7 1.2e-86 290.1 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Bac_luciferase PF00296.15 AEO59351.1 - 1.8e-60 204.6 4.8 2.3e-60 204.2 3.3 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase MFS_1 PF07690.11 AEO59352.1 - 1.8e-09 36.7 35.4 1.8e-09 36.7 24.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 AEO59352.1 - 4.9e-05 22.8 4.8 4.9e-05 22.8 3.3 2.5 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 Pyr_redox_3 PF13738.1 AEO59353.1 - 1.8e-20 73.9 0.0 5.6e-20 72.2 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 AEO59353.1 - 1.2e-11 43.5 0.0 1e-10 40.4 0.0 2.1 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 AEO59353.1 - 7.1e-08 32.3 0.0 5.1e-07 29.6 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 AEO59353.1 - 4.4e-05 23.4 0.0 0.00013 21.9 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 AEO59353.1 - 0.00019 20.4 0.0 0.0019 17.2 0.0 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 AEO59353.1 - 0.00077 19.2 0.3 0.68 9.6 0.0 3.4 3 1 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 AEO59353.1 - 0.002 17.0 0.2 0.82 8.5 0.0 2.6 2 1 0 2 2 2 2 FAD dependent oxidoreductase Semialdhyde_dh PF01118.19 AEO59353.1 - 0.16 12.2 0.0 65 3.8 0.0 3.3 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain HI0933_like PF03486.9 AEO59353.1 - 0.26 9.7 0.3 1.9 6.8 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein MFS_1 PF07690.11 AEO59354.1 - 1.2e-28 99.8 29.1 1.5e-28 99.5 20.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Bac_luciferase PF00296.15 AEO59355.1 - 5.9e-62 209.5 2.1 1e-61 208.7 1.5 1.3 1 0 0 1 1 1 1 Luciferase-like monooxygenase Peptidase_S28 PF05577.7 AEO59356.1 - 1.8e-43 148.7 0.5 1.5e-33 116.0 0.0 2.0 2 0 0 2 2 2 2 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 AEO59356.1 - 0.00016 21.6 0.2 0.00038 20.4 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 AEO59356.1 - 0.025 13.7 0.0 0.046 12.9 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 AEO59356.1 - 0.091 12.5 0.1 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family A_deaminase PF00962.17 AEO59357.1 - 8.7e-41 139.9 0.0 2.4e-40 138.4 0.0 1.7 1 1 0 1 1 1 1 Adenosine/AMP deaminase Anoctamin PF04547.7 AEO59358.1 - 1.2e-100 337.3 0.0 1.4e-100 337.0 0.0 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel MFS_1 PF07690.11 AEO59359.1 - 7.1e-44 149.9 41.2 8.4e-44 149.7 27.5 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO59359.1 - 8e-15 54.3 13.9 8e-15 54.3 9.7 2.3 3 0 0 3 3 3 1 Sugar (and other) transporter Glyco_hydro_7 PF00840.15 AEO59361.1 - 6.9e-152 505.7 1.1 8.4e-152 505.4 0.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 IDO PF01231.13 AEO59365.1 - 2.8e-171 569.6 0.0 3.3e-171 569.4 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Vps23_core PF09454.5 AEO59366.1 - 1.7e-24 85.1 0.0 3.4e-24 84.2 0.0 1.5 1 0 0 1 1 1 1 Vps23 core domain UEV PF05743.8 AEO59366.1 - 4.7e-07 29.5 0.0 8.2e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 UEV domain NanE PF04131.9 AEO59367.1 - 0.05 12.5 0.0 0.077 11.9 0.0 1.2 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase STE2 PF02116.10 AEO59368.1 - 4e-29 101.5 18.8 4.5e-29 101.3 13.0 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR CN_hydrolase PF00795.17 AEO59369.1 - 2.3e-24 85.7 0.0 3.7e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Lipase_GDSL_2 PF13472.1 AEO59370.1 - 3.5e-14 53.3 0.2 4.4e-14 53.0 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 AEO59370.1 - 4.7e-14 52.7 0.0 6.8e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 AEO59370.1 - 0.0058 16.3 0.3 0.032 13.9 0.2 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Glyco_transf_8 PF01501.15 AEO59372.1 - 1.2e-07 31.3 0.0 1.5e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 AEO59372.1 - 0.032 13.6 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative Abhydrolase_4 PF08386.5 AEO59373.1 - 2.5e-20 72.2 0.0 7.1e-20 70.8 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 AEO59373.1 - 4.2e-13 49.3 0.0 2.9e-06 26.9 0.0 3.2 3 0 0 3 3 3 3 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 AEO59373.1 - 1.3e-05 25.1 6.3 1.3e-05 25.1 4.3 3.1 3 1 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO59373.1 - 0.00096 18.9 0.0 0.0087 15.8 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Fungal_trans PF04082.13 AEO59374.1 - 1.2e-23 83.3 0.0 1.6e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO59374.1 - 4.1e-08 32.9 10.4 6.9e-08 32.2 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MR_MLE_C PF13378.1 AEO59375.1 - 2.6e-22 78.9 0.0 8.4e-22 77.2 0.0 1.8 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE PF01188.16 AEO59375.1 - 1.5e-13 51.0 0.0 4.3e-13 49.5 0.0 1.7 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 AEO59375.1 - 8.3e-10 38.6 0.0 1.3e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain adh_short PF00106.20 AEO59376.1 - 1.1e-24 87.2 1.9 1.4e-24 86.8 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO59376.1 - 4.9e-20 72.3 0.0 5.9e-20 72.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO59376.1 - 1.9e-09 37.4 0.4 3e-09 36.8 0.3 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 AEO59376.1 - 0.021 14.5 0.1 0.038 13.7 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 AEO59376.1 - 0.11 11.6 0.1 0.31 10.1 0.0 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Hce2 PF14856.1 AEO59377.1 - 7.5e-09 35.3 0.0 1.3e-08 34.6 0.0 1.4 1 1 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor CopD PF05425.8 AEO59378.1 - 0.027 14.6 0.0 0.028 14.6 0.0 1.0 1 0 0 1 1 1 0 Copper resistance protein D RVT_1 PF00078.22 AEO59380.1 - 0.017 14.4 0.0 0.017 14.4 0.0 1.0 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2353 PF09789.4 AEO59381.1 - 0.0012 18.1 5.1 0.0012 18.1 3.6 2.4 1 1 0 2 2 2 1 Uncharacterized coiled-coil protein (DUF2353) DUF904 PF06005.7 AEO59381.1 - 0.0046 17.2 6.4 0.0046 17.2 4.4 4.2 4 1 0 4 4 2 1 Protein of unknown function (DUF904) bZIP_1 PF00170.16 AEO59381.1 - 0.0095 15.8 6.4 0.0095 15.8 4.4 4.3 4 0 0 4 4 4 1 bZIP transcription factor ADIP PF11559.3 AEO59381.1 - 0.011 15.7 10.2 0.011 15.7 7.1 3.2 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 AEO59381.1 - 0.028 13.9 35.6 0.015 14.9 11.0 3.3 1 1 2 3 3 3 0 IncA protein Tropomyosin_1 PF12718.2 AEO59381.1 - 0.11 12.2 35.7 0.089 12.6 20.5 2.9 1 1 2 3 3 3 0 Tropomyosin like EzrA PF06160.7 AEO59381.1 - 0.43 8.6 19.0 0.65 8.1 13.2 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF3584 PF12128.3 AEO59381.1 - 0.45 7.7 23.1 0.61 7.3 16.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Tropomyosin PF00261.15 AEO59381.1 - 1.3 8.0 34.7 29 3.6 24.0 2.3 1 1 0 1 1 1 0 Tropomyosin YlqD PF11068.3 AEO59381.1 - 3.4 7.7 20.6 0.83 9.6 3.4 2.7 1 1 0 2 2 2 0 YlqD protein TPR_MLP1_2 PF07926.7 AEO59381.1 - 4.5 7.0 26.4 1.1 9.0 10.9 3.2 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein DUF4200 PF13863.1 AEO59381.1 - 7.8 6.4 35.1 0.99 9.3 11.0 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) GAS PF13851.1 AEO59381.1 - 8.6 5.5 29.4 0.036 13.2 12.4 2.5 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding FlaC_arch PF05377.6 AEO59381.1 - 8.7 6.3 17.7 0.065 13.1 3.6 3.3 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) CCDC155 PF14662.1 AEO59381.1 - 9.5 5.7 32.1 20 4.7 7.5 3.1 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 APH PF01636.18 AEO59382.1 - 3.8e-14 52.9 2.8 8.6e-13 48.5 1.7 2.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 AEO59382.1 - 0.00091 18.2 0.0 0.0014 17.6 0.0 1.2 1 0 0 1 1 1 1 Fructosamine kinase Choline_kinase PF01633.15 AEO59382.1 - 0.17 11.4 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Tyrosinase PF00264.15 AEO59383.1 - 1.8e-34 119.8 0.0 5e-34 118.3 0.0 1.7 1 1 0 1 1 1 1 Common central domain of tyrosinase HLH PF00010.21 AEO59384.1 - 5.3e-06 26.0 0.0 1.1e-05 24.9 0.0 1.6 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Methyltransf_11 PF08241.7 AEO59385.1 - 3.9e-25 88.1 0.0 6e-25 87.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO59385.1 - 1.8e-23 82.8 0.0 2.2e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO59385.1 - 1.4e-18 67.1 0.0 2.3e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO59385.1 - 7.7e-18 64.7 0.0 1.1e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AEO59385.1 - 6.9e-15 54.7 0.0 9.1e-15 54.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 AEO59385.1 - 5.4e-14 52.7 0.0 8.9e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO59385.1 - 1.1e-13 51.3 0.0 1.9e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO59385.1 - 1.3e-11 44.5 1.8 2.5e-11 43.6 1.2 1.4 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 AEO59385.1 - 6.7e-06 25.5 0.0 0.087 12.0 0.0 2.2 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain PCMT PF01135.14 AEO59385.1 - 8.5e-06 25.4 0.0 1.2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 AEO59385.1 - 1.8e-05 24.1 0.0 2.8e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.1 AEO59385.1 - 0.00019 21.1 0.0 0.00027 20.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 AEO59385.1 - 0.0021 17.1 0.0 0.0048 15.9 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase MetW PF07021.7 AEO59385.1 - 0.0025 17.2 0.0 0.0053 16.1 0.0 1.5 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.6 AEO59385.1 - 0.0064 15.2 0.0 0.0099 14.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) RrnaAD PF00398.15 AEO59385.1 - 0.0069 15.4 0.0 0.009 15.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase GCD14 PF08704.5 AEO59385.1 - 0.0083 15.6 0.0 0.012 15.1 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_29 PF03141.11 AEO59385.1 - 0.0086 14.4 0.1 0.019 13.3 0.0 1.5 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_3 PF01596.12 AEO59385.1 - 0.027 13.5 0.0 0.038 13.0 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_28 PF02636.12 AEO59385.1 - 0.027 13.8 0.0 0.042 13.2 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase PrmA PF06325.8 AEO59385.1 - 0.057 12.5 0.0 0.083 11.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DREV PF05219.7 AEO59385.1 - 0.057 12.2 0.0 0.11 11.3 0.0 1.5 1 1 0 1 1 1 0 DREV methyltransferase RRM_1 PF00076.17 AEO59386.1 - 4.3e-44 147.9 0.0 3e-15 55.6 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO59386.1 - 1.7e-43 146.4 0.0 5.5e-17 61.4 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO59386.1 - 7e-21 73.8 0.0 2.8e-09 36.6 0.0 4.7 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 AEO59386.1 - 4.8e-05 23.0 0.0 0.0025 17.5 0.0 2.9 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Lsm_interact PF05391.6 AEO59386.1 - 0.046 13.1 2.3 0.063 12.7 0.1 2.3 2 0 0 2 2 2 0 Lsm interaction motif RRM_3 PF08777.6 AEO59386.1 - 0.21 11.4 2.1 0.73 9.7 0.0 2.8 3 0 0 3 3 3 0 RNA binding motif Pro_racemase PF05544.6 AEO59387.1 - 3e-62 210.3 0.0 4e-62 209.9 0.0 1.2 1 0 0 1 1 1 1 Proline racemase HA2 PF04408.18 AEO59389.1 - 4.5e-17 61.9 0.0 1.5e-16 60.2 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 AEO59389.1 - 1.5e-12 47.1 0.0 3.5e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 AEO59389.1 - 1.6e-09 37.4 0.0 3.3e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 AEO59389.1 - 1.4e-08 34.9 0.2 2.1e-07 31.1 0.1 2.7 2 0 0 2 2 2 1 AAA domain OB_NTP_bind PF07717.11 AEO59389.1 - 1.2e-07 31.5 0.0 2.8e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_29 PF13555.1 AEO59389.1 - 0.0024 17.3 0.0 0.0079 15.6 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.1 AEO59389.1 - 0.034 13.5 0.0 0.097 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 AEO59389.1 - 0.039 14.2 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 ABC transporter NB-ARC PF00931.17 AEO59389.1 - 0.11 11.2 0.0 0.22 10.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain KaiC PF06745.8 AEO59389.1 - 0.12 11.5 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 KaiC DUF258 PF03193.11 AEO59389.1 - 0.22 10.6 0.0 0.53 9.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 AEO59389.1 - 0.41 10.9 0.0 0.41 10.9 0.0 2.6 3 0 0 3 3 2 0 AAA domain DUF3554 PF12074.3 AEO59390.1 - 1.5e-96 323.8 11.1 3.3e-95 319.3 2.5 5.0 4 0 0 4 4 4 1 Domain of unknown function (DUF3554) HEAT PF02985.17 AEO59390.1 - 3.6e-41 135.5 39.4 0.0042 17.0 0.0 24.1 28 0 0 28 28 26 8 HEAT repeat HEAT_2 PF13646.1 AEO59390.1 - 3.9e-38 129.6 66.7 7.5e-10 38.9 0.1 18.3 12 4 6 18 18 17 10 HEAT repeats HEAT_EZ PF13513.1 AEO59390.1 - 1.4e-31 108.1 73.1 3.2e-07 30.6 0.0 25.3 18 5 8 28 28 26 8 HEAT-like repeat Vac14_Fab1_bd PF12755.2 AEO59390.1 - 4.1e-14 52.7 0.0 0.97 9.8 0.0 10.7 8 4 5 13 13 12 3 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 AEO59390.1 - 5.6e-14 52.0 0.0 0.0032 16.8 0.0 6.8 5 1 4 9 9 9 4 CLASP N terminal ParcG PF10274.4 AEO59390.1 - 1.7e-13 50.8 0.9 0.00011 22.1 0.0 5.7 5 1 0 5 5 5 3 Parkin co-regulated protein Cnd1 PF12717.2 AEO59390.1 - 3.6e-10 39.9 0.6 5.3 6.8 0.2 9.2 7 3 4 11 11 10 2 non-SMC mitotic condensation complex subunit 1 UME PF08064.8 AEO59390.1 - 3.8e-07 30.0 0.0 6.4 6.7 0.0 7.6 5 2 2 8 8 8 1 UME (NUC010) domain Ipi1_N PF12333.3 AEO59390.1 - 2.2e-06 27.5 0.7 0.0014 18.5 0.0 5.7 6 0 0 6 6 5 1 Rix1 complex component involved in 60S ribosome maturation Cohesin_HEAT PF12765.2 AEO59390.1 - 0.0061 16.4 9.9 17 5.4 0.2 7.3 8 0 0 8 8 8 0 HEAT repeat associated with sister chromatid cohesion DUF2454 PF10521.4 AEO59390.1 - 0.021 13.8 0.1 2.6 6.9 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2454) MMS19_C PF12460.3 AEO59390.1 - 0.16 10.6 10.5 0.73 8.4 0.3 5.3 5 1 0 5 5 5 0 RNAPII transcription regulator C-terminal HEAT_PBS PF03130.11 AEO59390.1 - 0.62 10.6 30.5 2.2 8.9 0.1 11.4 10 0 0 10 10 10 0 PBS lyase HEAT-like repeat XPC-binding PF09280.6 AEO59390.1 - 0.87 9.0 5.8 0.43 10.0 0.0 3.6 4 0 0 4 4 4 0 XPC-binding domain Arm PF00514.18 AEO59390.1 - 2.5 8.0 15.5 36 4.3 0.0 9.3 9 2 2 11 11 10 0 Armadillo/beta-catenin-like repeat Ribosomal_L19e PF01280.15 AEO59391.1 - 1.2e-61 206.8 8.1 1.2e-61 206.8 5.6 1.9 1 1 1 2 2 2 1 Ribosomal protein L19e HTH_17 PF12728.2 AEO59391.1 - 0.092 13.0 0.3 1.1 9.5 0.1 2.9 2 1 0 2 2 2 0 Helix-turn-helix domain DUF4337 PF14235.1 AEO59391.1 - 8.6 6.1 8.1 13 5.6 5.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) SHMT PF00464.14 AEO59392.1 - 2.6e-196 651.7 0.0 3e-196 651.5 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 AEO59392.1 - 0.00053 19.2 0.0 0.0013 17.9 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 AEO59392.1 - 0.0032 16.2 0.0 0.0047 15.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Isochorismatase PF00857.15 AEO59393.1 - 2e-28 99.4 0.0 1.2e-27 96.9 0.0 2.2 1 1 0 1 1 1 1 Isochorismatase family 2OG-FeII_Oxy_2 PF13532.1 AEO59393.1 - 2.8e-26 92.5 2.7 3.7e-26 92.1 0.0 2.2 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily GST_C_2 PF13410.1 AEO59393.1 - 0.0032 17.3 0.3 0.01 15.7 0.2 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 AEO59393.1 - 0.0036 17.7 0.0 0.012 16.0 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Nop14 PF04147.7 AEO59393.1 - 0.41 8.5 18.5 0.61 7.9 12.9 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 AEO59393.1 - 0.59 8.1 16.8 0.87 7.5 11.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 AEO59393.1 - 0.96 7.8 25.7 1.5 7.1 17.8 1.2 1 0 0 1 1 1 0 Daxx Family MIP-T3 PF10243.4 AEO59393.1 - 1.1 7.6 40.4 0.57 8.5 26.7 1.4 1 1 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF3439 PF11921.3 AEO59393.1 - 4.5 7.0 11.2 9.9 5.9 7.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SAPS PF04499.10 AEO59393.1 - 5.7 5.4 11.3 9.2 4.7 7.8 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Mucin PF01456.12 AEO59393.1 - 6.7 6.4 23.3 0.095 12.4 10.6 2.1 2 0 0 2 2 1 0 Mucin-like glycoprotein SSP160 PF06933.6 AEO59393.1 - 7.2 4.4 13.5 14 3.5 9.4 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Hid1 PF12722.2 AEO59393.1 - 8.2 3.9 11.9 12 3.3 8.3 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein LRR_4 PF12799.2 AEO59394.1 - 9.6e-18 63.3 3.2 5.1e-06 25.9 0.2 4.4 2 2 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AEO59394.1 - 1.4e-16 59.9 7.6 2.4e-08 33.5 0.4 3.7 1 1 2 4 4 4 4 Leucine rich repeat LRR_1 PF00560.28 AEO59394.1 - 3.5e-10 38.4 7.8 0.29 11.3 0.0 6.3 6 0 0 6 6 6 3 Leucine Rich Repeat Pkinase PF00069.20 AEO59394.1 - 0.00052 19.2 0.0 0.0019 17.3 0.0 1.8 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO59394.1 - 0.0014 17.8 0.0 0.11 11.5 0.0 2.6 2 1 0 2 2 2 1 Protein tyrosine kinase SSP160 PF06933.6 AEO59394.1 - 0.0055 14.7 15.3 0.0081 14.2 10.6 1.1 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 Ribosomal_60s PF00428.14 AEO59394.1 - 0.02 15.2 0.8 0.02 15.2 0.6 2.6 3 0 0 3 3 3 0 60s Acidic ribosomal protein LRR_7 PF13504.1 AEO59394.1 - 0.023 14.8 12.7 2.1 8.8 0.4 5.3 6 0 0 6 6 4 0 Leucine rich repeat Mucin PF01456.12 AEO59394.1 - 0.038 13.7 15.4 0.08 12.7 10.7 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein LRR_6 PF13516.1 AEO59394.1 - 0.066 13.3 5.4 2 8.7 0.2 3.7 3 1 0 3 3 3 0 Leucine Rich repeat DUF3439 PF11921.3 AEO59394.1 - 0.51 10.0 16.8 0.97 9.2 11.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Bromo_TP PF07524.8 AEO59395.1 - 4.4e-16 58.3 0.0 7.3e-16 57.6 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TAF8_C PF10406.4 AEO59395.1 - 1.3e-11 44.3 0.4 1.6e-05 24.8 0.2 2.7 2 0 0 2 2 2 2 Transcription factor TFIID complex subunit 8 C-term WD40 PF00400.27 AEO59396.1 - 1.8e-61 201.9 23.2 1.2e-11 43.9 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 AEO59396.1 - 7.1e-07 27.7 4.8 0.16 10.0 0.1 3.9 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 AEO59396.1 - 0.046 12.0 0.0 5.3 5.2 0.1 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain DUF3112 PF11309.3 AEO59397.1 - 5.7e-38 130.2 0.1 5.7e-38 130.2 0.1 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF3112) Cation_ATPase_C PF00689.16 AEO59397.1 - 0.011 15.2 2.6 0.045 13.2 0.0 2.3 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus ASFV_J13L PF05568.6 AEO59397.1 - 0.068 12.7 0.8 0.11 12.0 0.1 1.6 1 1 0 1 1 1 0 African swine fever virus J13L protein Colicin_V PF02674.11 AEO59397.1 - 1.3 8.9 10.3 0.053 13.3 1.9 2.3 2 1 0 2 2 2 0 Colicin V production protein TRAM_LAG1_CLN8 PF03798.11 AEO59397.1 - 5.7 6.4 9.3 0.077 12.5 0.6 2.1 3 1 0 3 3 3 0 TLC domain Rax2 PF12768.2 AEO59398.1 - 0.067 12.3 0.0 0.098 11.8 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Ribosomal_L22 PF00237.14 AEO59399.1 - 1.6e-13 50.4 0.1 5.8e-06 26.1 0.0 2.7 2 0 0 2 2 2 2 Ribosomal protein L22p/L17e DUF3439 PF11921.3 AEO59399.1 - 1.1 8.9 7.4 2 8.1 5.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) CFEM PF05730.6 AEO59400.1 - 2.4e-12 46.5 6.0 5.7e-12 45.2 4.1 1.7 1 0 0 1 1 1 1 CFEM domain MLANA PF14991.1 AEO59400.1 - 0.031 14.3 0.9 0.39 10.7 0.0 2.6 3 0 0 3 3 3 0 Protein melan-A TFIIA PF03153.8 AEO59400.1 - 0.18 11.6 8.0 0.22 11.3 5.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF605 PF04652.11 AEO59400.1 - 0.31 10.3 14.3 0.42 9.9 9.9 1.3 1 0 0 1 1 1 0 Vta1 like FAM176 PF14851.1 AEO59400.1 - 1.1 8.9 6.0 68 3.1 0.0 2.1 2 0 0 2 2 2 0 FAM176 family DUF566 PF04484.7 AEO59400.1 - 1.1 8.6 15.4 1.5 8.2 10.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Presenilin PF01080.12 AEO59400.1 - 1.2 7.8 6.2 1.8 7.2 4.3 1.3 1 0 0 1 1 1 0 Presenilin Herpes_BLLF1 PF05109.8 AEO59400.1 - 2 6.3 38.0 2.4 6.0 26.4 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Macoilin PF09726.4 AEO59400.1 - 2.4 6.3 15.7 3 6.0 10.9 1.1 1 0 0 1 1 1 0 Transmembrane protein Dicty_REP PF05086.7 AEO59400.1 - 3.6 5.2 7.6 3.8 5.1 5.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SOG2 PF10428.4 AEO59400.1 - 4 5.9 21.6 6 5.4 15.0 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Peptidase_S64 PF08192.6 AEO59400.1 - 4.2 5.5 8.9 4.6 5.4 6.1 1.1 1 0 0 1 1 1 0 Peptidase family S64 NDUFA12 PF05071.11 AEO59404.1 - 0.13 12.7 0.2 0.24 11.8 0.1 1.4 1 0 0 1 1 1 0 NADH ubiquinone oxidoreductase subunit NDUFA12 Hydrolase_6 PF13344.1 AEO59405.1 - 2.6e-22 78.6 0.0 7.1e-22 77.2 0.0 1.8 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 AEO59405.1 - 6.5e-11 41.7 0.0 3.4e-10 39.5 0.0 2.3 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 AEO59405.1 - 0.01 16.2 0.0 0.041 14.2 0.0 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF1237 PF06824.6 AEO59406.1 - 2.1e-158 527.4 0.0 2.4e-158 527.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) WD40 PF00400.27 AEO59408.1 - 1.2e-53 177.1 5.1 5.1e-10 38.8 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 AEO59408.1 - 0.0034 16.1 1.1 0.63 8.7 0.2 3.4 1 1 2 3 3 3 3 Nup133 N terminal like TRAPP PF04051.11 AEO59409.1 - 1.1e-36 125.6 0.0 1.3e-36 125.3 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF4250 PF14056.1 AEO59409.1 - 0.12 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) p450 PF00067.17 AEO59410.1 - 1e-56 192.4 0.0 1.2e-56 192.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CFEM PF05730.6 AEO59411.1 - 2.3e-13 49.7 10.9 4.7e-13 48.7 7.5 1.6 1 0 0 1 1 1 1 CFEM domain RBP_receptor PF14752.1 AEO59411.1 - 0.14 10.4 9.9 0.051 11.9 0.7 2.1 1 1 1 2 2 2 0 Retinol binding protein receptor Alpha_kinase PF02816.13 AEO59413.1 - 1.1e-41 142.6 0.0 1.3e-41 142.3 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family LisH PF08513.6 AEO59414.1 - 0.21 11.4 0.3 0.43 10.4 0.2 1.5 1 0 0 1 1 1 0 LisH ADH_N PF08240.7 AEO59416.1 - 2e-09 37.1 0.0 5e-09 35.8 0.0 1.5 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AEO59416.1 - 1.1e-07 31.4 0.1 2.1e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox PF00070.22 AEO59416.1 - 0.1 13.0 0.0 0.64 10.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_16 PF00722.16 AEO59417.1 - 1.6e-18 66.6 0.0 3.2e-18 65.6 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 AEO59417.1 - 2.3e-07 29.3 0.0 0.00016 19.9 0.0 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) DUF1400 PF07176.6 AEO59420.1 - 0.032 14.1 0.5 0.16 11.8 0.1 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1400) UvrD_C_2 PF13538.1 AEO59421.1 - 0.00017 21.7 0.0 0.00048 20.2 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain HET PF06985.6 AEO59423.1 - 1.1e-08 35.3 0.0 2.6e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_S8 PF00082.17 AEO59424.1 - 1.1e-46 159.2 12.2 1.5e-46 158.8 8.5 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 AEO59424.1 - 6.8e-15 55.4 0.1 1.1e-14 54.6 0.1 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 APH PF01636.18 AEO59426.1 - 5.6e-08 32.8 0.1 1.5e-07 31.4 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 AEO59426.1 - 2.5e-06 26.9 0.0 3.8e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.20 AEO59426.1 - 0.00084 18.5 0.0 0.0012 18.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO59426.1 - 0.037 13.0 0.0 0.049 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Kdo PF06293.9 AEO59426.1 - 0.049 12.6 0.0 0.076 12.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 AEO59426.1 - 0.2 11.2 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase FlgN PF05130.7 AEO59428.1 - 0.0051 17.0 1.4 0.0081 16.4 1.0 1.4 1 0 0 1 1 1 1 FlgN protein APG6 PF04111.7 AEO59428.1 - 0.0056 15.7 0.5 0.0069 15.4 0.3 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 OmpH PF03938.9 AEO59428.1 - 0.036 13.9 0.4 0.047 13.6 0.3 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1599 PF07659.6 AEO59428.1 - 0.086 12.9 2.6 5.7 7.0 0.1 2.3 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1599) DUF1664 PF07889.7 AEO59428.1 - 0.15 11.8 0.3 0.23 11.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Fzo_mitofusin PF04799.8 AEO59428.1 - 0.2 11.0 1.1 0.29 10.5 0.8 1.2 1 0 0 1 1 1 0 fzo-like conserved region DUF724 PF05266.9 AEO59428.1 - 0.22 11.1 3.0 0.61 9.6 2.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF724) CALCOCO1 PF07888.6 AEO59428.1 - 1.5 7.0 9.3 1.9 6.7 6.5 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2852 PF11014.3 AEO59428.1 - 2.5 8.0 6.2 2.6 8.0 3.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) FlgN PF05130.7 AEO59432.1 - 0.0051 17.0 1.4 0.0081 16.4 1.0 1.4 1 0 0 1 1 1 1 FlgN protein APG6 PF04111.7 AEO59432.1 - 0.0056 15.7 0.5 0.0069 15.4 0.3 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 OmpH PF03938.9 AEO59432.1 - 0.036 13.9 0.4 0.047 13.6 0.3 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1599 PF07659.6 AEO59432.1 - 0.086 12.9 2.6 5.7 7.0 0.1 2.3 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1599) DUF1664 PF07889.7 AEO59432.1 - 0.15 11.8 0.3 0.23 11.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Fzo_mitofusin PF04799.8 AEO59432.1 - 0.2 11.0 1.1 0.29 10.5 0.8 1.2 1 0 0 1 1 1 0 fzo-like conserved region DUF724 PF05266.9 AEO59432.1 - 0.22 11.1 3.0 0.61 9.6 2.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF724) CALCOCO1 PF07888.6 AEO59432.1 - 1.5 7.0 9.3 1.9 6.7 6.5 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2852 PF11014.3 AEO59432.1 - 2.5 8.0 6.2 2.6 8.0 3.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) HHH_2 PF12826.2 AEO59433.1 - 0.15 11.9 1.0 5.2 7.0 0.1 2.1 1 1 1 2 2 2 0 Helix-hairpin-helix motif Alpha_GJ PF03229.8 AEO59434.1 - 0.00012 22.3 7.2 0.00012 22.3 5.0 2.5 2 0 0 2 2 2 1 Alphavirus glycoprotein J Glyco_hydro_2_N PF02837.13 AEO59435.1 - 1.9e-38 131.6 0.0 6.3e-35 120.2 0.0 2.4 2 0 0 2 2 2 2 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 AEO59435.1 - 3.4e-27 95.1 0.0 7e-27 94.1 0.0 1.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 AEO59435.1 - 7e-16 58.6 0.0 1.6e-15 57.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.1 AEO59435.1 - 1.3e-06 28.6 0.0 0.00024 21.3 0.0 2.9 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain Big_1 PF02369.11 AEO59435.1 - 0.43 10.4 0.1 0.43 10.4 0.0 3.3 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 1) Acetyltransf_1 PF00583.19 AEO59436.1 - 0.00014 21.8 0.0 0.00022 21.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AEO59436.1 - 0.00022 21.3 0.0 0.00038 20.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 AEO59436.1 - 0.097 12.5 0.0 0.5 10.2 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Aa_trans PF01490.13 AEO59437.1 - 9.7e-73 244.9 22.5 1.1e-72 244.7 15.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Lyase_1 PF00206.15 AEO59438.1 - 6.2e-89 298.2 0.0 8.3e-89 297.8 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 AEO59438.1 - 4e-28 97.2 0.4 1.3e-27 95.6 0.0 2.1 2 0 0 2 2 2 1 Argininosuccinate lyase C-terminal Abhydrolase_6 PF12697.2 AEO59439.1 - 1.1e-11 45.1 0.5 1e-10 41.8 0.3 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO59439.1 - 6.8e-08 32.3 0.0 7.7e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AEO59439.1 - 1.2e-06 28.3 0.0 1.1e-05 25.2 0.0 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.15 AEO59439.1 - 0.048 13.0 0.0 0.078 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Pyr_redox_3 PF13738.1 AEO59441.1 - 1.1e-17 64.8 0.0 3.2e-16 59.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 AEO59441.1 - 1.6e-07 30.5 1.6 5.7e-06 25.4 0.0 2.9 2 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 AEO59441.1 - 8.2e-07 29.1 0.0 2.3e-06 27.6 0.0 1.6 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 AEO59441.1 - 0.00082 18.5 0.6 0.012 14.6 0.0 2.3 2 1 0 2 2 2 1 FAD binding domain DAO PF01266.19 AEO59441.1 - 0.003 16.5 1.3 3.9 6.2 0.1 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 AEO59441.1 - 0.0043 17.4 0.3 0.18 12.2 0.1 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 AEO59441.1 - 0.017 14.0 1.5 0.15 10.9 0.3 2.4 2 1 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 AEO59441.1 - 0.054 13.2 0.8 15 5.3 0.0 3.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding CPSase_L_chain PF00289.17 AEO59441.1 - 0.13 12.3 0.0 14 5.8 0.0 2.6 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain NifU_N PF01592.11 AEO59443.1 - 1.3e-52 177.0 0.0 1.6e-52 176.7 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain UCH PF00443.24 AEO59444.1 - 1.2e-39 136.0 0.0 1.8e-39 135.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 AEO59444.1 - 2e-25 88.6 10.1 3.8e-20 71.7 1.5 3.0 2 0 0 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 AEO59444.1 - 3.1e-19 68.2 0.1 3.5e-09 36.2 0.1 2.7 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.1 AEO59444.1 - 1.4e-17 64.1 0.0 4.1e-14 52.7 0.0 2.6 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Lar_restr_allev PF14354.1 AEO59444.1 - 6.3 7.1 9.5 1 9.7 0.0 3.9 3 1 0 3 3 3 0 Restriction alleviation protein Lar HORMA PF02301.13 AEO59445.1 - 1.5e-44 151.9 0.1 2.1e-44 151.4 0.0 1.2 1 0 0 1 1 1 1 HORMA domain Suf PF05843.9 AEO59445.1 - 0.0041 16.8 0.6 0.0046 16.7 0.4 1.1 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) MSA-2c PF12238.3 AEO59445.1 - 0.01 15.5 0.7 0.014 15.0 0.5 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c Stirrup PF09061.1 AEO59445.1 - 0.061 13.2 0.0 0.62 10.0 0.0 2.1 2 0 0 2 2 2 0 Stirrup DUF913 PF06025.7 AEO59445.1 - 0.12 11.0 0.6 0.17 10.5 0.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF1754 PF08555.5 AEO59445.1 - 8.2 7.0 13.2 0.24 12.0 4.4 1.8 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) Syndecan PF01034.15 AEO59446.1 - 0.037 13.6 0.9 0.065 12.8 0.6 1.3 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.5 AEO59446.1 - 1.1 8.6 4.6 2 7.8 3.2 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF2613 PF11021.3 AEO59446.1 - 3.1 7.5 14.8 0.17 11.5 4.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) Ank_2 PF12796.2 AEO59447.1 - 1.4e-21 76.5 0.7 4.7e-09 36.4 0.1 4.2 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 AEO59447.1 - 1.1e-17 64.0 1.6 4.1e-07 30.3 0.0 4.9 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.25 AEO59447.1 - 2.6e-14 52.2 12.4 0.00013 21.5 0.1 7.4 7 1 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.1 AEO59447.1 - 2.4e-13 49.8 7.2 4.1e-05 23.6 0.2 5.8 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 AEO59447.1 - 4.5e-12 44.9 4.5 0.023 14.9 0.0 7.3 8 0 0 8 8 8 3 Ankyrin repeat F-box PF00646.28 AEO59447.1 - 0.012 15.2 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.2 AEO59447.1 - 0.053 13.2 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 F-box-like DUF3439 PF11921.3 AEO59447.1 - 5 6.9 7.8 9.5 5.9 5.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) TRP PF06011.7 AEO59448.1 - 6.8e-145 482.9 35.1 8.3e-145 482.6 24.3 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 AEO59448.1 - 4.1e-39 133.8 0.1 7.1e-39 133.0 0.0 1.4 1 0 0 1 1 1 1 ML-like domain DUF1049 PF06305.6 AEO59448.1 - 0.13 11.7 0.1 0.13 11.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Cauli_VI PF01693.11 AEO59449.1 - 5.4e-33 112.7 9.5 9e-17 60.8 1.2 2.3 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.19 AEO59449.1 - 4e-29 101.6 0.0 8.1e-29 100.6 0.0 1.5 1 0 0 1 1 1 1 RNase H Aldolase_II PF00596.16 AEO59451.1 - 2.2e-19 69.7 0.1 5.5e-19 68.4 0.0 1.6 1 1 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain AceK PF06315.6 AEO59452.1 - 0.15 10.3 0.0 0.17 10.1 0.0 1.0 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) DEAD PF00270.24 AEO59453.1 - 6.8e-47 159.0 0.0 8.4e-44 149.0 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO59453.1 - 4.6e-30 103.3 0.0 5e-29 99.9 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 AEO59453.1 - 0.02 13.3 0.0 0.02 13.3 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1253) CMS1 PF14617.1 AEO59453.1 - 0.29 10.1 0.0 0.29 10.1 0.0 3.4 2 1 1 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit FAM60A PF15396.1 AEO59453.1 - 0.7 9.6 17.1 1.2 8.7 11.9 1.5 1 0 0 1 1 1 0 Protein Family FAM60A Daxx PF03344.10 AEO59453.1 - 1.8 6.9 29.0 2.4 6.5 20.1 1.1 1 0 0 1 1 1 0 Daxx Family MIP-T3 PF10243.4 AEO59453.1 - 3 6.1 45.3 4.8 5.5 31.4 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SOBP PF15279.1 AEO59453.1 - 8.4 6.6 13.1 14 5.9 9.1 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Rft-1 PF04506.8 AEO59455.1 - 4.8e-83 279.3 0.3 3e-50 171.1 0.2 2.0 2 0 0 2 2 2 2 Rft protein Polysacc_synt PF01943.12 AEO59455.1 - 5.2e-05 22.6 9.4 5.2e-05 22.6 6.5 2.7 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein CfAFP PF05264.6 AEO59456.1 - 3.4 7.4 16.5 0.36 10.6 7.9 2.0 1 1 1 2 2 2 0 Choristoneura fumiferana antifreeze protein (CfAFP) DUF1049 PF06305.6 AEO59457.1 - 0.055 12.9 0.2 0.18 11.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) ADH_N PF08240.7 AEO59458.1 - 3.2e-28 97.6 2.1 5.2e-28 96.9 1.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.1 AEO59458.1 - 4.7e-09 35.7 1.2 4.7e-09 35.7 0.8 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N PF00107.21 AEO59458.1 - 2e-07 30.6 0.0 0.00016 21.2 0.0 2.6 2 0 0 2 2 2 2 Zinc-binding dehydrogenase Transferase PF02458.10 AEO59460.1 - 3e-15 55.6 0.0 5.6e-14 51.4 0.0 2.3 2 1 0 2 2 2 1 Transferase family LysM PF01476.15 AEO59463.1 - 6.4e-22 77.1 0.1 4e-06 26.6 0.0 3.7 3 1 0 3 3 3 3 LysM domain NLPC_P60 PF00877.14 AEO59463.1 - 0.00026 20.7 0.6 0.65 9.8 0.0 2.9 3 0 0 3 3 3 2 NlpC/P60 family PAN_4 PF14295.1 AEO59463.1 - 0.022 14.4 6.3 2.3 7.9 0.1 3.7 3 0 0 3 3 3 0 PAN domain Keratin_matx PF04579.7 AEO59464.1 - 0.49 10.7 4.9 0.76 10.0 2.5 1.9 1 1 1 2 2 2 0 Keratin, high-sulphur matrix protein Glyco_hydro_18 PF00704.23 AEO59465.1 - 1.2e-42 146.6 0.3 1.9e-42 145.9 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Hce2 PF14856.1 AEO59465.1 - 6.4e-31 106.1 1.8 1.9e-30 104.6 1.3 1.9 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor LysM PF01476.15 AEO59465.1 - 2.5e-12 46.4 0.1 4.8e-05 23.1 0.1 2.6 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.14 AEO59465.1 - 0.00036 20.4 2.8 0.00036 20.4 2.0 3.1 2 0 0 2 2 2 1 Chitin recognition protein Radial_spoke PF04712.7 AEO59465.1 - 0.62 8.7 0.1 1.2 7.7 0.1 1.4 1 0 0 1 1 1 0 Radial spokehead-like protein Metallophos_2 PF12850.2 AEO59466.1 - 2.7e-12 46.7 0.0 4.8e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 AEO59466.1 - 1.9e-08 33.9 0.0 4.7e-08 32.6 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase TonB_dep_Rec PF00593.19 AEO59466.1 - 0.035 14.0 0.0 0.061 13.2 0.0 1.3 1 0 0 1 1 1 0 TonB dependent receptor MARVEL PF01284.18 AEO59467.1 - 0.0013 18.5 23.1 0.0018 18.0 16.0 1.3 1 0 0 1 1 1 1 Membrane-associating domain Lectin_N PF03954.9 AEO59467.1 - 0.077 12.3 0.6 0.11 11.9 0.5 1.3 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain BPD_transp_1 PF00528.17 AEO59467.1 - 0.68 9.4 15.3 0.15 11.5 2.7 2.3 1 1 2 3 3 3 0 Binding-protein-dependent transport system inner membrane component FAD_binding_3 PF01494.14 AEO59468.1 - 5e-83 279.0 0.0 7.1e-83 278.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 AEO59468.1 - 0.001 19.0 0.2 0.0039 17.1 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 AEO59468.1 - 0.0042 16.0 0.1 0.012 14.4 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 AEO59468.1 - 0.011 14.6 0.2 0.016 14.0 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.1 AEO59468.1 - 0.019 14.9 1.7 0.041 13.9 1.2 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 AEO59468.1 - 0.019 14.0 0.2 0.031 13.3 0.1 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 AEO59468.1 - 0.071 13.1 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 AEO59468.1 - 0.077 11.9 0.2 0.14 11.0 0.2 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.22 AEO59468.1 - 0.11 12.9 0.1 0.32 11.4 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 AEO59468.1 - 0.17 11.9 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain 2OG-FeII_Oxy PF03171.15 AEO59469.1 - 5.3e-14 52.3 0.0 8.1e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 AEO59469.1 - 3.4e-10 40.4 0.0 5.8e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal M20_dimer PF07687.9 AEO59471.1 - 0.00018 21.2 0.1 0.00038 20.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain SnoaL PF07366.7 AEO59472.1 - 0.0034 16.9 0.4 0.82 9.2 0.1 2.3 1 1 0 2 2 2 2 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 AEO59472.1 - 0.0086 16.4 0.2 0.031 14.6 0.1 1.9 1 1 0 1 1 1 1 SnoaL-like domain Polysacc_lyase PF14099.1 AEO59473.1 - 4.2e-47 160.6 2.1 4.8e-47 160.4 1.5 1.0 1 0 0 1 1 1 1 Polysaccharide lyase DUF1080 PF06439.6 AEO59473.1 - 0.012 15.5 1.0 0.042 13.7 0.7 1.9 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1080) Abhydrolase_3 PF07859.8 AEO59474.1 - 1.1e-44 152.5 0.0 1.4e-44 152.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 AEO59474.1 - 1.5e-09 37.1 1.2 6.4e-09 35.0 0.8 1.7 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S15 PF02129.13 AEO59474.1 - 0.011 15.1 0.1 3.3 7.0 0.0 2.2 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_5 PF12695.2 AEO59474.1 - 0.021 14.6 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family NODP PF07684.7 AEO59474.1 - 0.031 13.8 0.0 0.085 12.4 0.0 1.7 1 0 0 1 1 1 0 NOTCH protein DUF1989 PF09347.5 AEO59475.1 - 7e-53 178.4 0.0 8.7e-53 178.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) LVIVD PF08309.6 AEO59476.1 - 0.02 13.8 0.0 8.3 5.4 0.0 3.8 4 0 0 4 4 4 0 LVIVD repeat Beta_propel PF09826.4 AEO59476.1 - 0.16 10.2 0.1 0.37 9.0 0.1 1.5 1 1 0 1 1 1 0 Beta propeller domain p450 PF00067.17 AEO59477.1 - 3.5e-46 157.6 0.0 5.2e-46 157.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Pyr_redox_2 PF07992.9 AEO59477.1 - 9.3e-29 100.7 2.4 1.5e-28 100.0 1.6 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AEO59477.1 - 9.3e-12 45.1 2.9 1.2e-10 41.6 0.3 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AEO59477.1 - 1.8e-07 31.4 0.2 0.00055 20.0 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.1 AEO59477.1 - 8.6e-06 25.9 0.1 3.2e-05 24.1 0.1 2.0 1 0 0 1 1 1 1 Reductase C-terminal NAD_binding_9 PF13454.1 AEO59477.1 - 0.45 10.2 4.2 6.2 6.5 0.0 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding DUF1467 PF07330.7 AEO59478.1 - 0.14 11.9 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1467) Glyco_hydro_61 PF03443.9 AEO59482.1 - 1.8e-25 90.0 0.0 2.2e-25 89.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MFS_1 PF07690.11 AEO59483.1 - 1.8e-43 148.6 55.7 1e-41 142.8 36.3 3.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 AEO59483.1 - 9.5e-21 73.6 10.8 9.5e-21 73.6 7.5 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 AEO59483.1 - 2.1e-15 56.2 12.8 2.1e-15 56.2 8.8 3.4 1 1 2 3 3 3 2 Sugar (and other) transporter Pox_A14 PF05767.7 AEO59483.1 - 1.3e-05 25.0 0.7 5.5e-05 23.0 0.5 2.1 1 0 0 1 1 1 1 Poxvirus virion envelope protein A14 OATP PF03137.15 AEO59483.1 - 0.0041 15.2 2.4 0.94 7.4 0.2 2.4 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family DUF3318 PF11780.3 AEO59483.1 - 0.032 13.8 0.6 0.071 12.6 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) AP_endonuc_2 PF01261.19 AEO59485.1 - 9.2e-36 123.1 0.0 1.4e-35 122.5 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel PTS_2-RNA PF01885.11 AEO59486.1 - 1e-11 44.4 0.0 2.4e-11 43.3 0.0 1.6 1 1 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Methyltransf_31 PF13847.1 AEO59487.1 - 7e-06 25.7 0.0 8.3e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO59487.1 - 1.2e-05 25.8 0.1 1.8e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO59487.1 - 0.00024 21.5 0.0 0.00051 20.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO59487.1 - 0.0015 18.2 0.0 0.0023 17.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO59487.1 - 0.0092 16.4 0.1 0.015 15.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO59487.1 - 0.018 15.3 0.0 0.025 14.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain NKWYS PF10364.4 AEO59487.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Putative capsular polysaccharide synthesis protein RhoGAP PF00620.22 AEO59488.1 - 1.2e-12 47.7 0.0 2.1e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain SCIMP PF15050.1 AEO59488.1 - 0.053 13.4 0.6 0.1 12.4 0.4 1.4 1 0 0 1 1 1 0 SCIMP protein SnoaL PF07366.7 AEO59489.1 - 8.8e-15 54.4 0.0 4.7e-13 48.8 0.0 2.2 2 0 0 2 2 2 2 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 AEO59489.1 - 2.2e-08 34.4 0.0 1.8e-07 31.4 0.0 2.0 2 0 0 2 2 2 1 SnoaL-like domain NMO PF03060.10 AEO59490.1 - 3.6e-41 141.4 5.9 3.9e-32 111.7 1.1 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.20 AEO59490.1 - 2.8e-10 39.6 0.0 3.9e-05 22.6 2.5 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 AEO59490.1 - 4.5e-06 25.7 5.0 8.2e-06 24.8 3.5 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 AEO59490.1 - 0.017 14.0 0.6 0.033 13.1 0.4 1.4 1 1 0 1 1 1 0 Conserved region in glutamate synthase DHO_dh PF01180.16 AEO59490.1 - 0.1 11.5 0.4 0.17 10.8 0.3 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase NIF PF03031.13 AEO59492.1 - 2.9e-37 127.7 0.0 4e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Metallophos PF00149.23 AEO59494.1 - 5.6e-11 42.2 1.3 9e-11 41.5 0.1 1.9 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Fungal_trans PF04082.13 AEO59495.1 - 5.9e-17 61.3 0.0 9.3e-17 60.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO59495.1 - 3.3e-08 33.3 7.1 6.7e-08 32.3 4.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CGI-121 PF08617.5 AEO59496.1 - 6.4e-46 155.9 0.0 7.4e-46 155.7 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Pro_dh PF01619.13 AEO59497.1 - 3.9e-40 137.7 0.0 5.9e-40 137.1 0.0 1.5 1 1 0 1 1 1 1 Proline dehydrogenase HTH_5 PF01022.15 AEO59497.1 - 0.091 12.4 0.0 0.26 10.9 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family bZIP_2 PF07716.10 AEO59497.1 - 0.74 9.6 5.9 1.6 8.6 4.1 1.5 1 0 0 1 1 1 0 Basic region leucine zipper Tim17 PF02466.14 AEO59498.1 - 0.17 11.9 6.8 0.37 10.8 4.7 1.7 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Romo1 PF10247.4 AEO59498.1 - 0.24 11.6 3.3 1 9.5 0.9 2.3 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Asp PF00026.18 AEO59500.1 - 1.6e-76 257.5 5.2 1.9e-76 257.3 3.6 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 AEO59500.1 - 2.4e-09 37.3 0.4 4.4e-08 33.2 0.0 2.7 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 AEO59500.1 - 4.4e-05 23.9 0.8 0.0044 17.4 0.2 2.8 2 1 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.1 AEO59500.1 - 0.017 14.6 0.0 0.042 13.4 0.0 1.7 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal OPT PF03169.10 AEO59502.1 - 5.1e-84 282.8 46.0 6.5e-84 282.5 31.9 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein RseC_MucC PF04246.7 AEO59502.1 - 0.15 11.6 0.0 0.15 11.6 0.0 3.4 4 0 0 4 4 4 0 Positive regulator of sigma(E), RseC/MucC Sugar_tr PF00083.19 AEO59503.1 - 1.2e-113 380.0 22.7 1.4e-113 379.8 15.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO59503.1 - 2.1e-24 85.8 61.4 1.2e-22 80.1 20.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF939 PF06081.6 AEO59503.1 - 0.055 13.3 0.4 0.055 13.3 0.3 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF939) BNR PF02012.15 AEO59504.1 - 2.5 8.2 7.4 0.28 11.1 0.2 3.3 3 0 0 3 3 3 0 BNR/Asp-box repeat MCM_N PF14551.1 AEO59505.1 - 0.051 14.0 0.0 0.15 12.5 0.0 1.7 2 0 0 2 2 2 0 MCM N-terminal domain Ribosomal_60s PF00428.14 AEO59505.1 - 0.53 10.7 11.1 17 5.8 3.4 3.2 3 0 0 3 3 3 0 60s Acidic ribosomal protein Beta-lactamase PF00144.19 AEO59506.1 - 6.7e-09 35.2 0.1 4.4e-08 32.5 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase Glyco_tranf_2_3 PF13641.1 AEO59508.1 - 2.9e-21 76.3 0.2 4.3e-21 75.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 AEO59508.1 - 3e-07 30.2 0.0 5.9e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 AEO59508.1 - 3.7e-07 29.6 0.1 1.3e-05 24.5 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.10 AEO59508.1 - 0.068 11.5 0.1 0.12 10.7 0.0 1.3 1 0 0 1 1 1 0 Chitin synthase Pex14_N PF04695.8 AEO59509.1 - 1.1 9.2 4.1 0.89 9.5 1.8 1.6 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3844 PF12955.2 AEO59510.1 - 9.2e-36 122.0 2.5 9.2e-36 122.0 1.8 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3844) Ten_N PF06484.7 AEO59510.1 - 0.018 14.1 0.3 0.033 13.3 0.2 1.4 1 0 0 1 1 1 0 Teneurin Intracellular Region NTR2 PF15458.1 AEO59511.1 - 5.4e-74 248.6 12.5 5.4e-74 248.6 8.7 1.7 2 0 0 2 2 2 1 Nineteen complex-related protein 2 Toxin_43 PF15604.1 AEO59511.1 - 0.012 15.6 0.8 0.012 15.6 0.6 1.9 2 0 0 2 2 2 0 Putative toxin 43 DUF948 PF06103.6 AEO59511.1 - 0.068 13.0 0.4 0.13 12.0 0.3 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Hemerythrin PF01814.18 AEO59511.1 - 0.11 12.6 5.7 0.57 10.3 4.0 2.0 1 1 0 1 1 1 0 Hemerythrin HHE cation binding domain WLM PF08325.5 AEO59511.1 - 0.76 9.6 3.7 2.3 8.0 2.5 1.9 1 0 0 1 1 1 0 WLM domain LSM PF01423.17 AEO59512.1 - 9.8e-20 69.8 0.9 1.1e-19 69.6 0.6 1.0 1 0 0 1 1 1 1 LSM domain DUF677 PF05055.7 AEO59512.1 - 0.03 12.9 0.0 0.03 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF677) Rhodanese PF00581.15 AEO59513.1 - 3.3e-07 30.6 0.0 5e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain BRO1 PF03097.13 AEO59514.1 - 0.0093 14.7 0.1 0.012 14.3 0.0 1.1 1 0 0 1 1 1 1 BRO1-like domain DUF4404 PF14357.1 AEO59514.1 - 0.66 10.4 4.4 1.1 9.6 3.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Ribosomal_60s PF00428.14 AEO59514.1 - 1.9 8.9 20.3 2.1 8.8 5.2 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF2076 PF09849.4 AEO59514.1 - 8.2 6.3 18.9 0.089 12.8 4.3 2.5 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Peptidase_C14 PF00656.17 AEO59515.1 - 1.4e-70 237.8 0.0 1.8e-70 237.4 0.0 1.1 1 0 0 1 1 1 1 Caspase domain RGS PF00615.14 AEO59516.1 - 0.00049 20.1 0.0 0.021 14.8 0.0 2.2 2 0 0 2 2 2 1 Regulator of G protein signaling domain 7TM-7TMR_HD PF07698.6 AEO59516.1 - 0.013 14.9 1.8 0.013 14.9 1.2 2.3 2 0 0 2 2 2 0 7TM receptor with intracellular HD hydrolase Zip PF02535.17 AEO59518.1 - 6e-51 173.3 0.2 8.2e-51 172.8 0.1 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter DUF3357 PF11837.3 AEO59518.1 - 0.35 10.7 1.2 16 5.3 0.0 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF3357) DOMON PF03351.12 AEO59519.1 - 0.0024 17.8 0.1 0.0033 17.3 0.1 1.3 1 0 0 1 1 1 1 DOMON domain DUF4276 PF14103.1 AEO59520.1 - 0.065 13.0 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4276) Pkinase PF00069.20 AEO59521.1 - 1.5e-28 99.7 0.0 2.5e-28 98.9 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO59521.1 - 2.2e-08 33.4 0.0 3.2e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 AEO59521.1 - 0.0013 17.8 0.1 0.0061 15.6 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AEO59521.1 - 0.053 13.2 0.3 0.24 11.1 0.2 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 AEO59521.1 - 0.054 12.4 0.0 0.095 11.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pox_ser-thr_kin PF05445.6 AEO59521.1 - 0.16 10.6 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.20 AEO59522.1 - 1.7e-13 50.3 0.0 2e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO59522.1 - 1.2e-10 40.8 0.0 1.9e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO59522.1 - 8e-07 28.2 0.0 1e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AEO59522.1 - 0.0001 22.1 0.6 0.00026 20.8 0.4 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 AEO59522.1 - 0.0011 18.0 0.0 0.002 17.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 AEO59522.1 - 0.019 14.3 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 RIO1 family DUF479 PF04336.7 AEO59522.1 - 0.03 14.4 0.1 0.12 12.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF479 TSC22 PF01166.13 AEO59522.1 - 0.083 12.8 0.3 0.37 10.8 0.1 2.1 2 0 0 2 2 2 0 TSC-22/dip/bun family zf-MYND PF01753.13 AEO59523.1 - 1.7e-10 40.5 10.1 3.3e-10 39.6 7.0 1.5 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 AEO59523.1 - 0.11 12.4 4.5 0.23 11.3 3.1 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF2413 PF10310.4 AEO59524.1 - 7.3e-149 496.3 0.0 8.3e-149 496.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) Flu_M1_C PF08289.6 AEO59524.1 - 0.012 15.5 0.3 0.058 13.4 0.2 2.1 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain HET PF06985.6 AEO59527.1 - 3.4e-23 82.3 9.5 3.8e-20 72.4 0.8 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Tir_receptor_C PF07489.6 AEO59527.1 - 0.32 10.7 3.7 0.6 9.8 2.5 1.4 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Ribosomal_L14 PF00238.14 AEO59528.1 - 3.3e-32 110.8 0.0 3.7e-32 110.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Malic_M PF03949.10 AEO59529.1 - 2.8e-80 269.5 0.0 3.6e-80 269.1 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 AEO59529.1 - 1.2e-64 217.2 0.0 2.1e-64 216.4 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Glyco_hydro_75 PF07335.6 AEO59530.1 - 3.2e-36 124.5 0.0 5.1e-36 123.9 0.0 1.3 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 Colipase-like PF15083.1 AEO59530.1 - 0.074 12.9 2.6 2 8.3 0.1 2.3 2 0 0 2 2 2 0 Colipase-like HET PF06985.6 AEO59531.1 - 0.03 14.4 0.4 0.052 13.7 0.3 1.4 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) DUF1399 PF07173.7 AEO59535.1 - 3.8e-22 79.0 0.2 8.4e-15 55.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1399) Glyco_hydro_11 PF00457.12 AEO59539.1 - 1.5e-78 262.3 16.1 1.9e-78 262.0 11.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 RHIM PF12721.2 AEO59539.1 - 0.012 15.9 6.5 9.9 6.6 0.0 3.8 3 0 0 3 3 3 0 RIP homotypic interaction motif SKG6 PF08693.5 AEO59541.1 - 0.00042 19.5 0.0 0.00042 19.5 0.0 2.4 3 0 0 3 3 3 1 Transmembrane alpha-helix domain DAP10 PF07213.6 AEO59541.1 - 0.0045 16.6 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 DAP10 membrane protein DUF4448 PF14610.1 AEO59541.1 - 0.018 14.5 0.0 0.044 13.2 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4448) EphA2_TM PF14575.1 AEO59541.1 - 0.024 15.0 0.2 0.054 13.8 0.0 1.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4328 PF14219.1 AEO59541.1 - 0.15 11.3 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) DUF1675 PF07897.6 AEO59541.1 - 0.17 11.7 3.7 0.27 11.0 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Granulin PF00396.13 AEO59541.1 - 1.3 9.2 7.0 1 9.5 1.8 2.4 2 0 0 2 2 2 0 Granulin Dicty_REP PF05086.7 AEO59541.1 - 2.7 5.6 5.4 3.5 5.2 3.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Atg14 PF10186.4 AEO59542.1 - 1.1e-21 77.0 0.0 1.8e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 AEO59542.1 - 0.00025 20.2 5.9 0.11 11.5 0.0 2.4 3 0 0 3 3 3 2 Autophagy protein Apg6 Pkinase PF00069.20 AEO59543.1 - 2.4e-06 26.8 0.6 3.2e-06 26.5 0.4 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO59543.1 - 0.011 14.8 0.2 0.012 14.6 0.1 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Ins_P5_2-kin PF06090.7 AEO59543.1 - 0.12 11.3 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Inositol-pentakisphosphate 2-kinase Ank_2 PF12796.2 AEO59544.1 - 3e-10 40.2 3.8 0.00012 22.2 0.6 3.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 AEO59544.1 - 1.1e-09 37.5 2.3 0.012 15.7 0.0 4.9 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.1 AEO59544.1 - 3e-08 33.6 7.4 0.00015 21.9 0.3 4.3 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 AEO59544.1 - 8.7e-08 32.4 5.1 0.032 14.7 0.0 4.4 3 2 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 AEO59544.1 - 4.1e-06 26.3 1.6 0.0036 17.0 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat CENP-T PF15511.1 AEO59544.1 - 0.036 13.3 5.9 0.057 12.6 4.1 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T FAM176 PF14851.1 AEO59544.1 - 0.053 13.1 6.8 0.18 11.4 3.0 2.1 2 0 0 2 2 2 0 FAM176 family DDHD PF02862.12 AEO59544.1 - 0.068 12.9 0.9 0.098 12.4 0.6 1.3 1 0 0 1 1 1 0 DDHD domain RXT2_N PF08595.6 AEO59544.1 - 0.08 12.7 9.0 0.035 13.8 2.2 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal DUF2956 PF11169.3 AEO59544.1 - 0.091 12.7 8.3 0.17 11.8 5.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) Gag_spuma PF03276.9 AEO59544.1 - 0.3 9.3 6.2 0.48 8.7 4.3 1.2 1 0 0 1 1 1 0 Spumavirus gag protein Serinc PF03348.10 AEO59544.1 - 0.37 9.4 1.3 0.5 9.0 0.9 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Peptidase_C58 PF03543.9 AEO59544.1 - 0.43 10.0 7.8 1.2 8.5 2.4 2.3 2 0 0 2 2 2 0 Yersinia/Haemophilus virulence surface antigen FLO_LFY PF01698.11 AEO59544.1 - 0.56 8.9 6.4 0.073 11.9 1.6 1.5 2 0 0 2 2 2 0 Floricaula / Leafy protein DUF2722 PF10846.3 AEO59544.1 - 3 6.7 10.4 14 4.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Med3 PF11593.3 AEO59544.1 - 5.6 6.1 8.7 8.6 5.4 6.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PGA2 PF07543.7 AEO59544.1 - 9.9 5.9 15.7 2.9 7.6 8.0 1.9 2 0 0 2 2 2 0 Protein trafficking PGA2 XLF PF09302.6 AEO59545.1 - 1.1e-41 142.4 0.0 1.7e-41 141.8 0.0 1.3 1 0 0 1 1 1 1 XLF (XRCC4-like factor) Fork_head PF00250.13 AEO59546.1 - 2.9e-16 59.2 0.1 8.2e-16 57.8 0.0 1.7 1 0 0 1 1 1 1 Fork head domain Zip PF02535.17 AEO59546.1 - 0.01 14.8 7.7 0.018 14.0 5.3 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3439 PF11921.3 AEO59546.1 - 0.03 14.0 1.6 0.074 12.8 1.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Suf PF05843.9 AEO59546.1 - 0.16 11.6 7.1 0.42 10.2 4.9 1.6 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RIC3 PF15361.1 AEO59546.1 - 0.62 10.2 8.9 4.2 7.5 6.2 2.4 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 DUF4175 PF13779.1 AEO59546.1 - 3.8 5.0 21.0 5.7 4.5 14.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) BAF1_ABF1 PF04684.8 AEO59546.1 - 4.6 5.9 41.7 0.51 9.1 25.8 1.6 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Cactin_mid PF10312.4 AEO59548.1 - 1.1e-65 220.5 5.2 1.4e-65 220.1 3.6 1.2 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.4 AEO59548.1 - 2.4e-55 185.4 4.7 3.7e-55 184.8 3.3 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein DUF1087 PF06465.8 AEO59548.1 - 0.003 17.4 5.2 0.047 13.6 0.5 2.6 2 0 0 2 2 2 2 Domain of Unknown Function (DUF1087) WD40 PF00400.27 AEO59549.1 - 1.4e-14 53.3 7.2 9.7e-09 34.7 0.6 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat Ribosomal_L37ae PF01780.14 AEO59549.1 - 0.027 14.3 2.6 0.071 12.9 1.8 1.6 1 0 0 1 1 1 0 Ribosomal L37ae protein family DUF3328 PF11807.3 AEO59550.1 - 1e-30 107.0 0.7 1.3e-30 106.7 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF2331 PF10093.4 AEO59550.1 - 0.054 12.2 0.1 0.07 11.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2331) Acetyltransf_1 PF00583.19 AEO59553.1 - 0.00018 21.5 0.6 0.13 12.3 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 AEO59553.1 - 0.00021 21.1 0.2 0.036 13.9 0.2 2.6 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 AEO59553.1 - 0.0055 16.8 0.0 0.014 15.5 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain adh_short PF00106.20 AEO59554.1 - 5.5e-25 88.2 0.0 7.8e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO59554.1 - 1.7e-24 86.9 0.0 2.1e-24 86.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO59554.1 - 9.3e-08 31.9 0.0 1.4e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 AEO59554.1 - 0.0023 17.4 0.0 0.0029 17.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 AEO59554.1 - 0.016 14.9 0.3 0.046 13.5 0.0 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 AEO59554.1 - 0.021 13.9 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF2974 PF11187.3 AEO59554.1 - 0.11 11.7 0.0 0.24 10.7 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) NUDIX PF00293.23 AEO59555.1 - 2e-15 56.6 0.1 2.4e-15 56.3 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain Fungal_trans PF04082.13 AEO59556.1 - 2.7e-19 69.0 0.2 4.6e-19 68.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO59556.1 - 2.8e-09 36.7 11.0 5.3e-09 35.8 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain cNMP_binding PF00027.24 AEO59557.1 - 1.6e-37 127.1 0.0 8.8e-19 67.1 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.1 AEO59557.1 - 5.4e-13 47.5 0.2 0.9 9.8 0.0 7.5 7 0 0 7 7 7 2 Leucine Rich repeat F-box-like PF12937.2 AEO59557.1 - 3.6e-06 26.5 0.2 1.5e-05 24.6 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 AEO59557.1 - 5.8e-06 25.8 2.4 7.3e-06 25.4 0.1 2.4 2 0 0 2 2 2 1 F-box domain LRR_8 PF13855.1 AEO59557.1 - 8.9e-05 22.1 1.0 1.2 8.9 0.0 4.2 4 1 1 5 5 5 3 Leucine rich repeat LRR_1 PF00560.28 AEO59557.1 - 9e-05 21.9 3.1 25 5.4 0.0 6.6 6 1 0 6 6 6 0 Leucine Rich Repeat LRR_4 PF12799.2 AEO59557.1 - 0.076 12.6 0.0 12 5.6 0.0 3.5 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 AEO59557.1 - 0.88 10.0 8.0 24 5.7 0.0 5.3 6 0 0 6 6 6 0 Leucine rich repeat Bax1-I PF01027.15 AEO59558.1 - 9.4e-33 113.5 9.6 1.4e-32 113.0 6.7 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Zip PF02535.17 AEO59559.1 - 2e-25 89.4 26.1 2e-12 46.7 1.5 4.4 3 1 2 5 5 5 3 ZIP Zinc transporter DUF1324 PF07038.6 AEO59559.1 - 0.075 13.0 0.0 0.59 10.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1324) DUF4106 PF13388.1 AEO59559.1 - 1.1 8.1 6.9 1.7 7.5 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Alpha-amyl_C2 PF07821.7 AEO59560.1 - 0.025 14.4 0.1 9 6.2 0.0 2.3 2 0 0 2 2 2 0 Alpha-amylase C-terminal beta-sheet domain SelP_N PF04592.9 AEO59560.1 - 2.3 7.5 7.6 3 7.1 5.3 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region PHD_2 PF13831.1 AEO59560.1 - 2.4 7.5 5.6 11 5.4 0.4 2.2 2 0 0 2 2 2 0 PHD-finger DUF2796 PF10986.3 AEO59560.1 - 5.1 7.0 16.9 9.9 6.1 11.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2796) NUDIX PF00293.23 AEO59562.1 - 2.1e-12 46.8 0.0 1.4e-08 34.4 0.0 2.9 3 0 0 3 3 3 2 NUDIX domain Slx4 PF09494.5 AEO59563.1 - 1.7e-24 85.3 0.0 3.1e-24 84.4 0.0 1.5 1 0 0 1 1 1 1 Slx4 endonuclease Ribosomal_S21e PF01249.13 AEO59564.1 - 1.8e-38 130.3 0.1 2e-38 130.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Nucleoplasmin PF03066.10 AEO59566.1 - 0.57 9.6 6.5 1.3 8.4 0.6 2.2 2 0 0 2 2 2 0 Nucleoplasmin CENP-B_dimeris PF09026.5 AEO59566.1 - 1.1 9.5 9.6 2.4 8.4 3.0 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain GST_N_3 PF13417.1 AEO59567.1 - 1.8e-11 44.1 0.1 4.5e-11 42.8 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 AEO59567.1 - 2.8e-08 33.6 0.1 6e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 AEO59567.1 - 8.6e-07 28.7 1.3 1.9e-06 27.6 0.9 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 AEO59567.1 - 0.0022 18.1 0.0 0.0086 16.2 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 AEO59567.1 - 0.041 14.3 0.1 0.083 13.3 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Octopine_DH PF02317.12 AEO59568.1 - 2.7e-36 124.5 0.0 3.7e-36 124.0 0.0 1.2 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain NAD_Gly3P_dh_N PF01210.18 AEO59568.1 - 4.5e-12 45.9 0.0 6.9e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 AEO59568.1 - 1.2e-07 32.0 0.0 2.6e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.9 AEO59568.1 - 0.00032 20.1 0.0 0.00064 19.1 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_8 PF13450.1 AEO59568.1 - 0.0008 19.3 0.2 0.0019 18.1 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.11 AEO59568.1 - 0.0012 18.3 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.14 AEO59568.1 - 0.0052 15.8 0.1 0.0069 15.4 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 AEO59568.1 - 0.026 13.3 0.5 0.04 12.7 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 AEO59568.1 - 0.027 12.9 0.1 0.04 12.4 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_2 PF07992.9 AEO59568.1 - 0.027 14.3 0.0 0.1 12.4 0.0 1.9 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AEO59568.1 - 0.067 13.2 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.10 AEO59568.1 - 0.092 12.5 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase UvrB PF12344.3 AEO59568.1 - 0.17 11.4 0.0 0.33 10.5 0.0 1.5 1 0 0 1 1 1 0 Ultra-violet resistance protein B Methyltransf_11 PF08241.7 AEO59569.1 - 7.3e-25 87.2 0.0 1.3e-24 86.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO59569.1 - 1e-23 83.5 0.0 1.3e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO59569.1 - 3.3e-21 75.6 0.0 4.9e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO59569.1 - 4.4e-18 65.8 0.0 7.3e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AEO59569.1 - 2.2e-17 62.9 0.0 4.4e-17 61.9 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 AEO59569.1 - 3.6e-17 62.6 0.0 7e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO59569.1 - 2.4e-15 56.7 0.0 3.8e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO59569.1 - 5.4e-13 49.0 0.0 1.1e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 AEO59569.1 - 1e-11 44.7 0.0 1.5e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 AEO59569.1 - 7.3e-08 31.9 0.0 1.2e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 AEO59569.1 - 1.7e-07 30.5 0.0 2.2e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.7 AEO59569.1 - 3.8e-07 29.6 0.0 2e-06 27.3 0.0 1.9 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_24 PF13578.1 AEO59569.1 - 8.5e-07 29.7 0.0 1.8e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 AEO59569.1 - 6.2e-05 22.5 0.0 0.00022 20.7 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_32 PF13679.1 AEO59569.1 - 0.00032 20.4 0.0 0.00061 19.4 0.0 1.4 2 0 0 2 2 1 1 Methyltransferase domain Fibrillarin PF01269.12 AEO59569.1 - 0.00032 19.6 0.0 0.00049 19.1 0.0 1.2 1 0 0 1 1 1 1 Fibrillarin FtsJ PF01728.14 AEO59569.1 - 0.00047 20.1 0.0 0.00062 19.7 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.8 AEO59569.1 - 0.00099 18.3 0.0 0.0014 17.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.15 AEO59569.1 - 0.0012 17.9 0.0 0.0018 17.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_9 PF08003.6 AEO59569.1 - 0.0026 16.5 0.0 0.0056 15.4 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) Nol1_Nop2_Fmu PF01189.12 AEO59569.1 - 0.0029 17.0 0.0 0.0047 16.3 0.0 1.3 1 0 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_4 PF02390.12 AEO59569.1 - 0.0062 15.6 0.0 0.023 13.7 0.0 1.8 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_29 PF03141.11 AEO59569.1 - 0.012 13.9 0.0 0.025 12.9 0.0 1.5 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase GCD14 PF08704.5 AEO59569.1 - 0.019 14.4 0.0 0.028 13.9 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_3 PF01596.12 AEO59569.1 - 0.051 12.6 0.0 0.076 12.0 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase NodS PF05401.6 AEO59569.1 - 0.094 12.0 0.0 0.2 11.0 0.0 1.5 1 1 0 1 1 1 0 Nodulation protein S (NodS) NmrA PF05368.8 AEO59570.1 - 0.0017 17.6 0.0 0.0025 17.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Prefoldin_2 PF01920.15 AEO59571.1 - 0.003 17.2 1.6 0.0038 16.9 1.1 1.2 1 0 0 1 1 1 1 Prefoldin subunit DUF1204 PF06721.6 AEO59571.1 - 0.032 13.4 0.2 0.037 13.2 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) DUF3086 PF11285.3 AEO59571.1 - 0.093 11.5 1.5 4.3 6.0 1.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3086) Zein-binding PF04576.10 AEO59571.1 - 0.22 11.6 3.0 0.27 11.3 2.1 1.1 1 0 0 1 1 1 0 Zein-binding Aldo_ket_red PF00248.16 AEO59572.1 - 3.9e-70 235.8 0.0 4.9e-70 235.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AP_endonuc_2 PF01261.19 AEO59572.1 - 0.044 13.0 0.0 0.27 10.4 0.0 2.3 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel Pkinase PF00069.20 AEO59575.1 - 4.9e-33 114.3 0.0 6.5e-33 113.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO59575.1 - 6.4e-16 58.2 0.0 1.1e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase ABC1 PF03109.11 AEO59575.1 - 0.017 15.0 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 ABC1 family SPT6_acidic PF14632.1 AEO59577.1 - 0.25 11.5 11.1 0.071 13.2 5.4 1.8 2 0 0 2 2 2 0 Acidic N-terminal SPT6 Nop14 PF04147.7 AEO59577.1 - 1 7.2 10.1 1.2 6.9 7.0 1.1 1 0 0 1 1 1 0 Nop14-like family CENP-B_dimeris PF09026.5 AEO59577.1 - 4.1 7.7 10.7 9.4 6.5 7.4 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Tub_2 PF04525.7 AEO59578.1 - 3.8e-14 52.5 0.0 4.9e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Tubby C 2 DUF2115 PF09888.4 AEO59578.1 - 0.069 13.2 0.1 0.092 12.8 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) DUF1680 PF07944.7 AEO59579.1 - 4.6e-129 431.0 0.0 5.2e-129 430.8 0.0 1.0 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) adh_short PF00106.20 AEO59581.1 - 3.2e-22 79.2 5.0 5.4e-22 78.4 3.5 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO59581.1 - 2.8e-10 40.1 2.2 3.5e-10 39.8 1.5 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 AEO59581.1 - 6e-08 32.7 0.1 7e-08 32.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase MDMPI_C PF07398.6 AEO59581.1 - 0.051 14.1 2.0 0.35 11.4 0.0 2.4 1 1 1 2 2 2 0 MDMPI C-terminal domain Sugar_tr PF00083.19 AEO59582.1 - 9e-74 248.6 22.4 1.1e-73 248.3 15.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO59582.1 - 7.9e-26 90.6 23.6 3.4e-22 78.6 10.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.14 AEO59582.1 - 2e-05 23.3 3.6 0.0011 17.5 0.3 2.3 2 0 0 2 2 2 2 LacY proton/sugar symporter MFS_2 PF13347.1 AEO59582.1 - 0.0012 17.3 8.5 0.0012 17.3 5.9 2.6 2 1 0 2 2 2 1 MFS/sugar transport protein Ferritin_2 PF13668.1 AEO59584.1 - 6.7e-15 55.2 0.0 9.5e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain DUF1996 PF09362.5 AEO59586.1 - 1.9e-87 292.8 0.3 2.3e-87 292.5 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Nudix_N_2 PF14803.1 AEO59586.1 - 0.095 12.4 0.0 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 Nudix N-terminal Beta-lactamase PF00144.19 AEO59587.1 - 0.00021 20.4 0.0 0.00022 20.3 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase NmrA PF05368.8 AEO59589.1 - 4.4e-33 114.4 0.0 5.2e-33 114.2 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 AEO59589.1 - 1e-13 51.7 0.1 1.3e-13 51.4 0.1 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 AEO59589.1 - 0.0027 17.1 0.0 0.0051 16.2 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family His_biosynth PF00977.16 AEO59589.1 - 0.0068 15.6 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Histidine biosynthesis protein KR PF08659.5 AEO59589.1 - 0.016 14.8 0.1 0.098 12.3 0.0 1.9 2 0 0 2 2 2 0 KR domain Semialdhyde_dh PF01118.19 AEO59589.1 - 0.07 13.4 0.1 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.11 AEO59589.1 - 0.1 13.1 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Snf7 PF03357.16 AEO59590.1 - 2e-45 154.2 11.0 2.5e-45 153.9 7.6 1.0 1 0 0 1 1 1 1 Snf7 CENP-F_leu_zip PF10473.4 AEO59590.1 - 0.011 15.5 9.4 1.2 8.9 7.6 2.5 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MscS_porin PF12795.2 AEO59590.1 - 0.012 14.9 14.7 0.84 8.8 6.7 2.7 1 1 2 3 3 3 0 Mechanosensitive ion channel porin domain DUF4201 PF13870.1 AEO59590.1 - 0.021 14.2 6.8 0.026 13.9 4.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) Reo_sigmaC PF04582.7 AEO59590.1 - 0.022 13.9 4.6 0.4 9.8 0.6 2.0 1 1 0 2 2 2 0 Reovirus sigma C capsid protein TBPIP PF07106.8 AEO59590.1 - 0.029 13.9 11.2 1.5 8.3 1.2 3.1 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) BLOC1_2 PF10046.4 AEO59590.1 - 0.063 13.4 10.9 0.11 12.6 2.2 3.1 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlxA PF14282.1 AEO59590.1 - 0.11 12.5 12.0 0.07 13.0 6.8 1.7 1 1 1 2 2 2 0 FlxA-like protein NuA4 PF09340.5 AEO59590.1 - 0.11 12.1 1.3 0.24 11.0 0.9 1.6 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 DUF150 PF02576.12 AEO59590.1 - 0.12 11.9 0.9 0.25 10.9 0.6 1.6 1 1 0 1 1 1 0 Uncharacterised BCR, YhbC family COG0779 COG2 PF06148.6 AEO59590.1 - 0.12 12.2 5.2 0.059 13.2 0.9 2.3 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 OmpH PF03938.9 AEO59590.1 - 0.14 12.0 14.8 0.11 12.3 6.9 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Rogdi_lz PF10259.4 AEO59590.1 - 0.15 11.1 2.3 0.19 10.8 0.6 1.7 2 0 0 2 2 2 0 Rogdi leucine zipper containing protein Seryl_tRNA_N PF02403.17 AEO59590.1 - 0.18 11.8 14.9 4.9 7.2 0.1 3.3 1 1 4 5 5 5 0 Seryl-tRNA synthetase N-terminal domain NPV_P10 PF05531.7 AEO59590.1 - 0.19 11.9 8.2 10 6.4 0.0 3.5 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4140 PF13600.1 AEO59590.1 - 0.2 12.1 9.7 0.29 11.5 0.0 3.8 2 1 2 4 4 4 0 N-terminal domain of unknown function (DUF4140) AAA_13 PF13166.1 AEO59590.1 - 0.22 9.9 7.8 0.66 8.3 5.4 1.7 1 1 0 1 1 1 0 AAA domain Mnd1 PF03962.10 AEO59590.1 - 0.27 10.8 9.5 0.69 9.5 6.2 1.9 1 1 0 1 1 1 0 Mnd1 family Baculo_PEP_C PF04513.7 AEO59590.1 - 0.66 9.7 8.3 1.7 8.4 0.1 2.4 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2205 PF10224.4 AEO59590.1 - 0.88 9.1 7.2 0.79 9.3 1.9 2.9 2 1 1 3 3 3 0 Predicted coiled-coil protein (DUF2205) IncA PF04156.9 AEO59590.1 - 0.9 9.1 11.9 4.8 6.7 3.3 2.6 1 1 1 2 2 2 0 IncA protein Mod_r PF07200.8 AEO59590.1 - 1.6 8.6 10.6 4.3 7.2 7.0 1.8 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF4094 PF13334.1 AEO59590.1 - 2.5 8.5 5.0 2.3 8.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) DUF4337 PF14235.1 AEO59590.1 - 3.3 7.5 8.1 0.39 10.5 2.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) WD40 PF00400.27 AEO59591.1 - 1.2e-36 123.2 9.6 3.2e-07 29.9 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 AEO59591.1 - 1.6e-12 46.9 3.4 1.6e-12 46.9 2.3 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 AEO59591.1 - 1.2e-07 31.1 2.3 2.2e-07 30.3 0.3 2.2 2 0 0 2 2 2 1 F-box domain Nup160 PF11715.3 AEO59591.1 - 0.00032 18.9 0.6 0.042 11.9 0.0 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 MgtE_N PF03448.12 AEO59591.1 - 0.006 16.8 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 MgtE intracellular N domain PH_10 PF15411.1 AEO59592.1 - 1e-44 151.4 0.1 1.8e-44 150.6 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.6 AEO59592.1 - 3.4e-33 113.5 0.0 6.7e-33 112.6 0.0 1.5 1 0 0 1 1 1 1 CDC24 Calponin RhoGEF PF00621.15 AEO59592.1 - 8.1e-33 113.8 0.0 1.3e-32 113.1 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.19 AEO59592.1 - 2.5e-11 43.0 0.0 5.5e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 PB1 domain Mid2 PF04478.7 AEO59595.1 - 0.00088 18.7 0.0 0.0017 17.7 0.0 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor DUF1517 PF07466.6 AEO59595.1 - 0.08 11.9 0.1 0.08 11.9 0.1 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF1517) DUF2650 PF10853.3 AEO59595.1 - 0.14 11.5 0.9 0.41 10.1 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2650) SKG6 PF08693.5 AEO59595.1 - 6.4 6.1 7.5 17 4.8 5.2 1.7 1 1 0 1 1 1 0 Transmembrane alpha-helix domain Skp1 PF01466.14 AEO59596.1 - 1.5e-20 73.0 0.1 3.2e-20 71.9 0.1 1.6 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 AEO59596.1 - 1.7e-05 24.8 0.0 4.1e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 Skp1 family, tetramerisation domain SCAN PF02023.12 AEO59596.1 - 0.092 12.2 0.0 0.21 11.0 0.0 1.7 2 0 0 2 2 2 0 SCAN domain TRI5 PF06330.6 AEO59597.1 - 4.6e-14 51.8 0.0 5.6e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) Terpene_synth_C PF03936.11 AEO59597.1 - 0.15 11.2 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain EcKinase PF02958.15 AEO59598.1 - 2.1e-19 69.8 0.0 1.3e-18 67.1 0.0 1.9 1 1 0 1 1 1 1 Ecdysteroid kinase APH PF01636.18 AEO59598.1 - 3.7e-09 36.6 0.4 4.7e-09 36.3 0.2 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 AEO59598.1 - 1.9e-07 30.1 0.1 3.3e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) GCOM2 PF15328.1 AEO59601.1 - 0.0013 18.5 3.2 0.0029 17.4 1.2 1.9 2 0 0 2 2 2 1 Putative GRINL1B complex locus protein 2 ADIP PF11559.3 AEO59601.1 - 0.042 13.7 11.6 1 9.2 0.0 2.8 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.4 AEO59601.1 - 0.075 12.8 8.7 0.079 12.8 1.0 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TBPIP PF07106.8 AEO59601.1 - 0.077 12.5 8.1 0.87 9.1 2.0 2.3 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CAGE1 PF15066.1 AEO59601.1 - 0.085 11.2 2.3 0.15 10.4 1.6 1.3 1 0 0 1 1 1 0 Cancer-associated gene protein 1 family DUF972 PF06156.8 AEO59601.1 - 0.19 12.1 4.1 2.9 8.2 1.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Spc24 PF08286.6 AEO59601.1 - 0.26 11.0 4.5 3.3 7.4 0.0 2.5 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 5_3_exonuc PF01367.15 AEO59601.1 - 0.49 10.6 2.2 1.4 9.2 1.2 1.9 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DivIC PF04977.10 AEO59601.1 - 0.59 9.6 12.5 0.28 10.7 4.3 2.4 2 0 0 2 2 2 0 Septum formation initiator MerR_2 PF13591.1 AEO59601.1 - 1.6 8.4 7.5 0.12 12.0 0.8 2.4 2 0 0 2 2 2 0 MerR HTH family regulatory protein IncA PF04156.9 AEO59601.1 - 2.4 7.7 9.9 10 5.6 0.2 2.3 2 0 0 2 2 2 0 IncA protein DUF2802 PF10975.3 AEO59601.1 - 2.9 7.7 6.9 1.4 8.6 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) Spc7 PF08317.6 AEO59601.1 - 3.9 6.0 9.1 4.9 5.7 0.2 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein SlyX PF04102.7 AEO59601.1 - 7.6 6.9 13.3 13 6.1 0.2 3.3 3 0 0 3 3 3 0 SlyX Prefoldin_2 PF01920.15 AEO59601.1 - 8.4 6.2 11.8 4.3 7.1 4.0 2.5 2 0 0 2 2 2 0 Prefoldin subunit Lipase_GDSL PF00657.17 AEO59602.1 - 1.8e-12 47.5 0.3 2.2e-12 47.2 0.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Glyco_transf_36 PF06165.6 AEO59604.1 - 3.4e-19 68.6 0.0 6.6e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 36 GT36_AF PF06205.6 AEO59604.1 - 1.7e-07 30.8 0.0 4e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase 36 associated family DUF608 PF04685.8 AEO59604.1 - 0.025 13.3 0.1 0.041 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF608 RVT_1 PF00078.22 AEO59605.1 - 0.001 18.4 0.2 0.0011 18.3 0.2 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) VAR1 PF05316.7 AEO59605.1 - 0.046 12.3 3.5 0.044 12.3 2.4 1.0 1 0 0 1 1 1 0 Mitochondrial ribosomal protein (VAR1) Dicty_CAR PF05462.6 AEO59606.1 - 9.2e-14 51.0 4.3 9.2e-14 51.0 3.0 1.4 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Git3 PF11710.3 AEO59606.1 - 8.1e-12 45.1 7.5 1.3e-11 44.4 5.2 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 AEO59606.1 - 2.8e-08 33.2 1.5 5.4e-08 32.2 1.0 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Zip PF02535.17 AEO59606.1 - 0.25 10.3 4.9 0.048 12.6 1.1 1.5 2 0 0 2 2 2 0 ZIP Zinc transporter DUF3638 PF12340.3 AEO59607.1 - 1.8e-88 295.4 0.0 3.5e-88 294.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 AEO59607.1 - 5.1e-17 60.7 0.8 1.2e-16 59.4 0.6 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) MspA PF09203.6 AEO59607.1 - 0.22 10.9 0.0 0.47 9.8 0.0 1.4 1 0 0 1 1 1 0 MspA COesterase PF00135.23 AEO59608.1 - 1e-42 146.6 0.0 1.2e-42 146.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 AEO59608.1 - 1.8e-06 27.7 0.0 2.2e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 AEO59608.1 - 0.11 11.6 0.3 0.16 11.1 0.2 1.1 1 0 0 1 1 1 0 Prolyl oligopeptidase family FA_hydroxylase PF04116.8 AEO59609.1 - 1e-15 58.1 21.5 1e-15 58.1 14.9 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Aldose_epim PF01263.15 AEO59610.1 - 2.6e-56 190.9 0.1 2.9e-56 190.7 0.1 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase DUF3405 PF11885.3 AEO59611.1 - 1e-143 479.1 1.0 1.2e-143 478.9 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) BATS PF06968.8 AEO59613.1 - 2.1e-30 104.3 0.1 6.9e-30 102.7 0.0 1.9 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 AEO59613.1 - 8e-17 61.9 0.2 1.3e-16 61.2 0.1 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Sld5 PF05916.6 AEO59614.1 - 4e-16 59.2 0.0 5.3e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein Sod_Fe_C PF02777.13 AEO59615.1 - 2.9e-40 136.3 0.1 4.5e-40 135.7 0.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 AEO59615.1 - 1.6e-31 108.3 0.6 2.6e-31 107.6 0.4 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Glycos_transf_1 PF00534.15 AEO59616.1 - 5e-24 84.6 0.0 1.3e-23 83.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 AEO59616.1 - 1.9e-11 44.2 0.0 3.7e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 AEO59616.1 - 3.1e-05 24.1 0.0 9.4e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Thymidylat_synt PF00303.14 AEO59617.1 - 2.1e-115 384.3 0.0 2.3e-115 384.2 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Globin PF00042.17 AEO59618.1 - 6.9e-09 36.0 0.0 1.3e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Globin FAD_binding_6 PF00970.19 AEO59618.1 - 3.1e-07 30.4 0.0 6.1e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 AEO59618.1 - 4.3e-05 24.0 0.0 8.4e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Protoglobin PF11563.3 AEO59618.1 - 0.00027 20.6 0.0 0.00059 19.5 0.0 1.6 1 1 0 1 1 1 1 Protoglobin ketoacyl-synt PF00109.21 AEO59619.1 - 1.9e-78 263.4 0.0 6.2e-78 261.7 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 AEO59619.1 - 9.6e-53 179.5 0.0 2.7e-52 178.1 0.0 1.7 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 AEO59619.1 - 4.1e-46 157.4 0.0 4.1e-46 157.4 0.0 1.8 2 0 0 2 2 2 1 Polyketide synthase dehydratase KR PF08659.5 AEO59619.1 - 1.4e-37 129.1 0.0 4.6e-37 127.4 0.0 1.9 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.17 AEO59619.1 - 2.7e-33 114.3 0.0 7.8e-33 112.8 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 AEO59619.1 - 9e-31 107.0 0.0 9e-31 107.0 0.0 3.0 4 0 0 4 4 4 1 short chain dehydrogenase PP-binding PF00550.20 AEO59619.1 - 1.5e-05 25.1 0.0 4.6e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Pyr_redox_3 PF13738.1 AEO59620.1 - 2.9e-24 86.2 0.0 7.4e-23 81.6 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 AEO59620.1 - 5.9e-15 54.4 0.1 1.7e-11 43.0 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 AEO59620.1 - 1.9e-13 50.7 0.0 5e-11 42.8 0.0 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 AEO59620.1 - 1.4e-09 37.3 0.5 7e-08 31.7 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 AEO59620.1 - 2.9e-05 23.9 0.0 0.00026 20.9 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 AEO59620.1 - 0.00017 20.8 0.0 0.00034 19.7 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 AEO59620.1 - 0.00026 19.9 0.0 0.0088 14.9 0.3 2.2 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 AEO59620.1 - 0.0019 16.7 0.3 0.025 13.0 0.1 2.5 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.17 AEO59620.1 - 0.017 14.0 1.2 0.31 9.8 0.2 2.6 3 0 0 3 3 3 0 Glucose inhibited division protein A Pyr_redox PF00070.22 AEO59620.1 - 0.017 15.5 0.3 4.2 7.8 0.0 3.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 AEO59620.1 - 0.018 14.6 0.1 0.045 13.3 0.0 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.1 AEO59620.1 - 0.026 14.2 0.5 4 7.2 0.1 3.0 2 1 1 3 3 3 0 FAD-NAD(P)-binding Thi4 PF01946.12 AEO59620.1 - 0.04 12.9 0.0 0.23 10.5 0.0 2.1 2 0 0 2 2 2 0 Thi4 family YtkA PF13115.1 AEO59620.1 - 0.047 14.0 0.2 31 5.0 0.0 3.8 4 0 0 4 4 4 0 YtkA-like TrkA_N PF02254.13 AEO59620.1 - 0.14 12.1 0.1 1 9.3 0.0 2.4 3 0 0 3 3 3 0 TrkA-N domain 3HCDH_N PF02737.13 AEO59620.1 - 0.2 11.2 0.1 17 4.9 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_hydro_18 PF00704.23 AEO59621.1 - 2.2e-05 24.0 0.0 3.2e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PGM_PMM_IV PF00408.15 AEO59621.1 - 0.058 13.4 0.4 0.35 10.9 0.1 2.1 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, C-terminal domain Serglycin PF04360.7 AEO59621.1 - 0.48 10.1 3.0 2.4 7.8 0.1 2.4 2 0 0 2 2 2 0 Serglycin DUF4175 PF13779.1 AEO59622.1 - 0.88 7.1 22.4 0.95 7.0 15.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Med15 PF09606.5 AEO59622.1 - 6.6 4.7 32.7 7.1 4.7 22.7 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Peptidase_S8 PF00082.17 AEO59624.1 - 1.8e-53 181.5 8.9 2.4e-53 181.1 6.2 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 AEO59624.1 - 2.8e-07 31.0 0.0 5e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 Lipase_GDSL_2 PF13472.1 AEO59625.1 - 0.0057 16.7 0.1 0.0083 16.2 0.1 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Zn_clus PF00172.13 AEO59626.1 - 2.3e-08 33.8 10.6 4.4e-08 32.9 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PHO4 PF01384.15 AEO59628.1 - 2.9e-113 377.8 16.5 3.5e-113 377.5 11.5 1.1 1 0 0 1 1 1 1 Phosphate transporter family GHMP_kinases_N PF00288.21 AEO59629.1 - 1.4e-17 63.5 0.0 3.3e-17 62.3 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GalKase_gal_bdg PF10509.4 AEO59629.1 - 0.0053 16.0 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Kdo PF06293.9 AEO59630.1 - 0.0023 17.0 0.1 0.0041 16.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Myb_DNA-bind_6 PF13921.1 AEO59632.1 - 2.3e-31 107.6 8.2 2.6e-15 56.2 0.2 3.0 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 AEO59632.1 - 2.4e-29 101.1 9.1 1e-13 51.1 0.2 3.1 3 0 0 3 3 3 3 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 AEO59632.1 - 0.027 14.6 5.2 1.9 8.7 0.2 2.5 2 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF3398 PF11878.3 AEO59632.1 - 0.033 14.0 0.8 1 9.2 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3398) Rap1_C PF11626.3 AEO59632.1 - 0.11 12.3 5.2 22 5.0 3.6 2.2 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain ketoacyl-synt PF00109.21 AEO59633.1 - 5.9e-80 268.4 0.4 1.3e-79 267.2 0.2 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 AEO59633.1 - 1.3e-46 159.4 0.0 5.5e-46 157.3 0.0 2.0 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 AEO59633.1 - 2.8e-37 127.1 0.2 9.7e-37 125.4 0.1 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 AEO59633.1 - 5.9e-20 72.4 0.1 1.5e-19 71.1 0.1 1.7 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.20 AEO59633.1 - 8.4e-19 67.6 1.6 2.6e-10 40.4 0.0 3.1 3 0 0 3 3 3 2 Phosphopantetheine attachment site PS-DH PF14765.1 AEO59633.1 - 8.1e-18 64.5 0.2 2.1e-17 63.2 0.1 1.7 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_5 PF12695.2 AEO59633.1 - 5.1e-07 29.5 1.4 0.00049 19.8 0.2 2.9 2 0 0 2 2 2 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 AEO59633.1 - 0.00018 20.5 0.1 0.0004 19.4 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain AMP-binding PF00501.23 AEO59634.1 - 5.7e-27 94.1 0.0 2.4e-26 92.1 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.7 AEO59634.1 - 1e-13 50.7 0.0 3e-13 49.2 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 AEO59634.1 - 5.6e-06 26.5 0.0 1.3e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.5 AEO59634.1 - 0.0041 16.7 0.2 0.01 15.5 0.2 1.7 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 AEO59634.1 - 0.012 15.4 1.3 0.012 15.4 0.9 2.5 3 0 0 3 3 3 0 short chain dehydrogenase AMP-binding_C PF13193.1 AEO59634.1 - 0.065 14.1 2.1 0.15 13.0 0.6 2.2 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain FAD_binding_3 PF01494.14 AEO59635.1 - 5e-58 196.8 0.0 1.3e-57 195.4 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 AEO59635.1 - 5.8e-06 26.2 0.2 2e-05 24.5 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Phe_hydrox_dim PF07976.7 AEO59635.1 - 3.6e-05 23.4 0.0 6.8e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Thi4 PF01946.12 AEO59635.1 - 0.00032 19.8 0.0 0.00055 19.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 AEO59635.1 - 0.00063 18.7 0.1 0.0013 17.7 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 AEO59635.1 - 0.00077 18.4 1.7 0.0079 15.0 0.9 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 AEO59635.1 - 0.0013 19.1 0.0 0.0028 18.0 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AEO59635.1 - 0.0017 18.4 0.0 0.003 17.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 AEO59635.1 - 0.0038 16.1 1.6 0.004 16.1 0.3 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.9 AEO59635.1 - 0.004 15.6 0.4 0.0059 15.1 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 AEO59635.1 - 0.011 15.6 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 AEO59635.1 - 0.029 14.0 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 AEO59635.1 - 0.058 13.1 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding K_oxygenase PF13434.1 AEO59635.1 - 0.093 11.6 0.1 0.32 9.8 0.0 1.8 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) ThiF PF00899.16 AEO59635.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 ThiF family Methyltransf_2 PF00891.13 AEO59636.1 - 9e-29 100.3 0.0 1.4e-28 99.6 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 AEO59636.1 - 0.0041 16.8 0.0 0.0081 15.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO59636.1 - 0.037 14.6 0.0 0.086 13.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain TrmB PF01978.14 AEO59636.1 - 0.053 13.2 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_5 PF01022.15 AEO59636.1 - 0.13 11.9 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Methyltransf_31 PF13847.1 AEO59636.1 - 0.13 11.8 0.0 0.26 10.8 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Abhydrolase_3 PF07859.8 AEO59637.1 - 5.8e-51 173.0 0.0 7.5e-51 172.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 AEO59637.1 - 5.8e-13 48.4 0.0 2e-12 46.6 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 AEO59637.1 - 7.1e-08 32.3 0.0 9.9e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AEO59637.1 - 1.7e-07 31.3 0.6 3e-07 30.5 0.4 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Eno-Rase_NADH_b PF12242.3 AEO59637.1 - 0.086 12.6 0.1 0.19 11.5 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Thioesterase PF00975.15 AEO59637.1 - 0.11 12.6 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_1 PF00561.15 AEO59637.1 - 0.14 11.6 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold AXE1 PF05448.7 AEO59637.1 - 0.2 10.1 0.7 1.1 7.6 0.2 2.0 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) adh_short PF00106.20 AEO59638.1 - 1.7e-20 73.6 0.4 9.1e-19 67.9 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO59638.1 - 1.3e-06 28.3 0.0 0.0088 15.8 0.0 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 AEO59638.1 - 4.8e-05 22.9 0.0 0.0002 20.9 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 AEO59638.1 - 0.0002 21.0 0.0 0.00032 20.4 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 AEO59638.1 - 0.16 10.9 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein MFS_1 PF07690.11 AEO59640.1 - 1.4e-29 102.9 48.7 2.3e-29 102.2 30.4 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Pkinase PF00069.20 AEO59641.1 - 2.2e-10 40.1 1.3 1.3e-09 37.5 0.5 2.0 1 1 1 2 2 2 1 Protein kinase domain APH PF01636.18 AEO59641.1 - 9.5e-06 25.5 0.1 1.5e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 AEO59641.1 - 0.00042 19.2 0.8 0.00054 18.8 0.1 1.4 2 0 0 2 2 2 1 Seadornavirus VP7 Pkinase_Tyr PF07714.12 AEO59641.1 - 0.0024 16.9 0.3 0.013 14.6 0.0 2.0 2 1 1 3 3 3 1 Protein tyrosine kinase RIO1 PF01163.17 AEO59641.1 - 0.0025 17.2 0.0 0.0035 16.7 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 AEO59641.1 - 0.014 14.4 0.1 0.024 13.6 0.1 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 AEO59641.1 - 0.029 13.9 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.1 AEO59641.1 - 0.048 12.6 0.0 0.066 12.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like WaaY PF06176.6 AEO59641.1 - 0.13 11.4 0.1 0.2 10.8 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) DUF1059 PF06348.6 AEO59641.1 - 6.6 6.6 6.8 0.27 11.0 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1059) GFA PF04828.9 AEO59642.1 - 1.1e-17 63.7 0.6 1.5e-17 63.3 0.4 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.6 AEO59642.1 - 2.7 7.5 7.3 0.24 10.9 0.4 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain SnoaL_2 PF12680.2 AEO59643.1 - 0.0038 17.6 0.1 0.0049 17.2 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain p450 PF00067.17 AEO59645.1 - 1.5e-05 23.7 0.0 0.0045 15.5 0.0 2.4 2 0 0 2 2 2 2 Cytochrome P450 FemAB PF02388.11 AEO59645.1 - 0.015 14.0 0.0 0.02 13.5 0.0 1.1 1 0 0 1 1 1 0 FemAB family DUF347 PF03988.7 AEO59646.1 - 0.27 11.1 1.3 8.3 6.3 0.4 2.4 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) TRAM_LAG1_CLN8 PF03798.11 AEO59647.1 - 8.9e-34 116.7 18.0 8.9e-34 116.7 12.4 1.6 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 AEO59647.1 - 2.9e-25 87.5 0.5 2.9e-25 87.5 0.3 1.9 2 0 0 2 2 2 1 TRAM1-like protein PEMT PF04191.8 AEO59647.1 - 0.012 15.6 2.3 0.012 15.6 1.6 2.3 3 0 0 3 3 3 0 Phospholipid methyltransferase AAA_12 PF13087.1 AEO59648.1 - 1.6e-32 112.5 0.0 2.8e-32 111.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 AEO59648.1 - 3.3e-24 85.7 0.0 7.5e-24 84.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AEO59648.1 - 1.3e-07 31.2 0.9 2.5e-06 27.1 0.0 3.1 3 0 0 3 3 3 1 Part of AAA domain DUF2075 PF09848.4 AEO59648.1 - 3.3e-06 26.3 0.1 0.006 15.6 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 AEO59648.1 - 0.001 19.0 0.2 0.0071 16.3 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.1 AEO59648.1 - 0.0024 17.4 0.0 0.011 15.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 AEO59648.1 - 0.011 15.5 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_25 PF13481.1 AEO59648.1 - 0.021 14.2 0.0 2.7 7.3 0.0 2.9 3 0 0 3 3 3 0 AAA domain UvrD_C_2 PF13538.1 AEO59648.1 - 0.025 14.6 0.0 0.061 13.4 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 AEO59648.1 - 0.03 13.6 0.0 0.077 12.2 0.0 1.6 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain DUF2235 PF09994.4 AEO59649.1 - 2.5e-107 358.3 0.9 3.3e-107 357.9 0.6 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) An_peroxidase PF03098.10 AEO59650.1 - 2e-86 290.5 0.0 5.3e-49 167.0 0.0 3.4 2 1 1 3 3 3 2 Animal haem peroxidase Colicin_C PF12106.3 AEO59651.1 - 7.6 6.2 7.4 5.8 6.5 0.4 2.7 2 1 0 2 2 2 0 Colicin C terminal ribonuclease domain Ank_2 PF12796.2 AEO59652.1 - 7.9e-32 109.4 7.3 1.9e-16 60.1 0.1 4.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 AEO59652.1 - 3e-30 102.5 15.7 4.5e-06 26.1 0.1 7.5 6 1 1 7 7 7 7 Ankyrin repeat Ank_4 PF13637.1 AEO59652.1 - 4.2e-22 78.1 5.3 1.1e-06 28.9 0.0 5.4 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 AEO59652.1 - 3e-17 60.9 10.0 0.0093 16.1 0.0 7.3 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.1 AEO59652.1 - 1.8e-14 53.4 12.7 4.4e-07 29.9 0.1 5.8 2 1 5 7 7 7 3 Ankyrin repeats (many copies) Adeno_knob PF00541.12 AEO59652.1 - 0.049 13.2 0.1 0.085 12.5 0.0 1.3 1 0 0 1 1 1 0 Adenoviral fibre protein (knob domain) HET PF06985.6 AEO59653.1 - 7.8e-30 103.8 5.1 1.3e-29 103.1 3.5 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) EcKinase PF02958.15 AEO59656.1 - 7.6e-19 67.9 0.0 8.9e-18 64.4 0.0 2.0 1 1 0 1 1 1 1 Ecdysteroid kinase APH PF01636.18 AEO59656.1 - 1.4e-09 38.0 0.2 2.7e-09 37.1 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 AEO59656.1 - 3.8e-07 29.1 0.0 5.2e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Fructosamin_kin PF03881.9 AEO59656.1 - 0.046 12.6 0.0 10 5.0 0.0 2.9 2 1 1 3 3 3 0 Fructosamine kinase adh_short_C2 PF13561.1 AEO59657.1 - 4.6e-25 88.7 0.0 5.7e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 AEO59657.1 - 9.9e-11 41.8 1.3 1.3e-10 41.4 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO59657.1 - 1.5e-06 27.9 0.3 3.9e-06 26.6 0.1 1.7 2 0 0 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.3 AEO59657.1 - 0.0002 21.0 0.4 0.00043 20.0 0.3 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 AEO59657.1 - 0.0028 17.1 0.1 0.004 16.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 AEO59657.1 - 0.0048 15.9 0.0 0.0084 15.1 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 AEO59657.1 - 0.0057 16.6 0.3 0.013 15.4 0.3 1.6 2 0 0 2 2 2 1 NADH(P)-binding Glyco_tran_WecB PF03808.8 AEO59657.1 - 0.027 13.8 0.0 0.047 13.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family 3HCDH_N PF02737.13 AEO59657.1 - 0.049 13.2 0.5 0.16 11.5 0.2 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3292 PF11696.3 AEO59658.1 - 6.5e-198 658.6 0.0 3.8e-196 652.8 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3292) PMI_typeI PF01238.16 AEO59659.1 - 6.8e-69 232.6 0.0 6.4e-67 226.1 0.0 2.0 1 1 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.14 AEO59659.1 - 5.1e-05 22.9 0.0 0.013 15.1 0.0 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_2 PF07883.6 AEO59659.1 - 5.5e-05 22.5 0.1 0.054 13.0 0.0 2.4 2 0 0 2 2 2 2 Cupin domain AraC_binding_2 PF14525.1 AEO59659.1 - 0.055 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 AraC-binding-like domain SET PF00856.23 AEO59660.1 - 2.7e-06 27.7 0.2 2.9e-05 24.4 0.1 2.3 1 1 0 1 1 1 1 SET domain SAF PF08666.7 AEO59660.1 - 0.095 13.1 0.2 14 6.1 0.0 2.6 3 0 0 3 3 3 0 SAF domain RVT_1 PF00078.22 AEO59661.1 - 5.7e-05 22.5 0.2 6.5e-05 22.3 0.2 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TPR_2 PF07719.12 AEO59663.1 - 0.053 13.4 0.0 0.093 12.6 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 AEO59663.1 - 0.091 12.4 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Pec_lyase_C PF00544.14 AEO59664.1 - 1.5e-40 138.8 5.6 2.5e-40 138.0 3.9 1.4 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 AEO59664.1 - 0.00019 21.2 7.4 0.0044 16.7 5.2 2.3 1 1 0 1 1 1 1 Right handed beta helix region DUF2945 PF11160.3 AEO59665.1 - 5.4e-15 54.9 0.4 1.8e-11 43.6 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2945) Inositol_P PF00459.20 AEO59669.1 - 9.4e-33 113.6 0.4 6.1e-25 88.0 0.1 2.1 2 0 0 2 2 2 2 Inositol monophosphatase family Cupin_2 PF07883.6 AEO59669.1 - 0.061 12.8 0.0 0.19 11.2 0.0 1.8 1 0 0 1 1 1 0 Cupin domain CorA PF01544.13 AEO59670.1 - 1.6e-06 27.3 8.7 1.6e-06 27.3 6.0 2.6 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein Zot PF05707.7 AEO59670.1 - 0.032 13.7 0.0 0.35 10.3 0.0 2.4 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) Zn_clus PF00172.13 AEO59672.1 - 4.2e-08 32.9 7.1 7.7e-08 32.1 4.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_6 PF12697.2 AEO59673.1 - 9.9e-07 28.8 0.1 5.5e-05 23.1 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO59673.1 - 0.1 12.3 0.1 0.65 9.7 0.0 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family Amidohydro_4 PF13147.1 AEO59674.1 - 1.4e-12 48.2 16.5 5.5e-11 43.0 0.7 3.4 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 AEO59674.1 - 1.9e-06 27.5 0.2 1.3e-05 24.9 0.1 2.4 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.15 AEO59674.1 - 2.2e-06 27.5 0.2 0.00016 21.4 0.0 2.4 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_3 PF07969.6 AEO59674.1 - 0.00099 18.4 4.8 0.0042 16.3 0.0 3.1 3 0 0 3 3 3 1 Amidohydrolase family APH PF01636.18 AEO59675.1 - 4e-18 66.0 3.3 5e-18 65.6 2.3 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 AEO59675.1 - 0.0014 18.2 0.0 0.002 17.7 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 AEO59675.1 - 0.14 11.2 0.0 0.31 10.1 0.0 1.5 2 0 0 2 2 2 0 Protein kinase domain zf-C2H2 PF00096.21 AEO59676.1 - 1.2e-15 56.8 46.6 2.9e-05 24.1 0.5 8.0 8 0 0 8 8 8 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AEO59676.1 - 6.5e-09 35.5 37.7 0.13 12.7 1.6 7.3 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 AEO59676.1 - 7e-09 35.5 30.2 0.0018 18.3 0.1 6.5 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 AEO59676.1 - 2.9e-07 30.4 31.5 0.00024 21.2 0.3 6.5 6 0 0 6 6 6 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 AEO59676.1 - 0.0013 18.7 5.5 0.0013 18.7 3.8 4.3 2 1 1 4 4 4 1 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.1 AEO59676.1 - 0.0065 16.6 0.7 0.0065 16.6 0.5 6.5 8 0 0 8 8 8 3 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.1 AEO59676.1 - 0.027 14.7 0.2 0.027 14.7 0.2 6.7 5 1 1 6 6 6 0 Zinc-finger double domain zf-DNA_Pol PF08996.5 AEO59676.1 - 0.092 12.0 0.3 0.092 12.0 0.2 4.0 2 1 2 4 4 4 0 DNA Polymerase alpha zinc finger Kinesin PF00225.18 AEO59677.1 - 5e-57 193.1 0.0 7.8e-57 192.4 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain AA_permease PF00324.16 AEO59679.1 - 4.6e-137 457.2 26.1 5.8e-137 456.9 18.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AEO59679.1 - 1.1e-41 142.8 24.5 1.5e-41 142.3 17.0 1.1 1 0 0 1 1 1 1 Amino acid permease Bac_rhodopsin PF01036.13 AEO59684.1 - 1.6e-34 119.1 18.1 2.2e-34 118.7 12.6 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DuoxA PF10204.4 AEO59684.1 - 0.0051 15.9 0.8 0.0051 15.9 0.6 2.3 2 1 0 2 2 2 1 Dual oxidase maturation factor DUF3432 PF11914.3 AEO59684.1 - 3.4 7.7 6.1 5.9 6.9 1.7 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3432) Aa_trans PF01490.13 AEO59685.1 - 2.8e-27 95.2 36.2 5.3e-27 94.3 25.1 1.4 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein PRT_C PF08372.5 AEO59685.1 - 0.12 11.9 0.9 4.8 6.6 0.1 2.9 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal Meth_synt_2 PF01717.13 AEO59686.1 - 3.4e-16 59.1 0.0 4.5e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 AEO59686.1 - 2.4e-05 23.7 0.0 0.019 14.2 0.0 3.0 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain DUF562 PF04763.7 AEO59686.1 - 0.14 11.3 0.1 0.36 10.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF562) Sugar_tr PF00083.19 AEO59687.1 - 6.7e-118 394.1 27.0 7.9e-118 393.8 18.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO59687.1 - 4.7e-20 71.5 38.8 2.6e-16 59.2 20.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 AEO59687.1 - 1.1e-08 33.9 29.1 0.00055 18.4 2.9 3.7 3 1 0 3 3 3 3 MFS/sugar transport protein DPBB_1 PF03330.13 AEO59689.1 - 9.2e-11 41.6 0.2 2.1e-10 40.4 0.1 1.7 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 AEO59689.1 - 0.0091 15.6 0.1 0.012 15.2 0.1 1.3 1 0 0 1 1 1 1 Barwin family Abhydrolase_4 PF08386.5 AEO59690.1 - 2e-18 66.1 0.0 4.3e-18 65.1 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 AEO59690.1 - 1.1e-15 57.8 0.0 5.8e-12 45.6 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 AEO59690.1 - 4.8e-11 42.9 9.0 1.8e-10 41.1 6.3 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO59690.1 - 0.00034 20.4 0.0 0.003 17.3 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family ATP_transf PF09830.4 AEO59691.1 - 2e-05 24.2 0.0 4e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase RVT_1 PF00078.22 AEO59692.1 - 0.0012 18.2 0.4 0.0013 18.1 0.3 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LVIVD PF08309.6 AEO59693.1 - 7.2e-07 28.1 2.7 0.57 9.2 0.0 4.5 4 0 0 4 4 4 4 LVIVD repeat Adaptin_N PF01602.15 AEO59694.1 - 1.2e-147 492.4 2.9 1.7e-147 491.9 2.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 AEO59694.1 - 1.7e-25 89.9 0.1 8.1e-25 87.6 0.0 2.2 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 AEO59694.1 - 7.4e-18 64.6 0.3 8e-07 29.2 0.0 5.4 2 2 3 5 5 5 3 HEAT repeats HEAT PF02985.17 AEO59694.1 - 5.2e-11 41.6 4.6 0.016 15.2 0.0 6.5 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.1 AEO59694.1 - 1.1e-05 25.7 1.0 1.9 9.0 0.0 5.5 6 1 0 6 6 6 1 HEAT-like repeat Arm PF00514.18 AEO59694.1 - 0.0079 15.9 1.9 16 5.5 0.0 5.6 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 AEO59694.1 - 0.062 12.6 0.1 2.2 7.5 0.0 3.1 2 1 1 3 3 3 0 CLASP N terminal AF0941-like PF14591.1 AEO59694.1 - 0.083 12.9 1.5 0.26 11.3 1.0 1.8 1 0 0 1 1 1 0 AF0941-like CAAP1 PF15335.1 AEO59694.1 - 0.097 12.8 0.6 0.57 10.4 0.1 2.4 2 0 0 2 2 2 0 Caspase activity and apoptosis inhibitor 1 Utp12 PF04003.7 AEO59694.1 - 0.13 12.1 0.8 0.82 9.6 0.1 2.6 2 0 0 2 2 2 0 Dip2/Utp12 Family Pox_A8 PF04745.7 AEO59695.1 - 0.1 11.4 0.1 0.11 11.4 0.0 1.0 1 0 0 1 1 1 0 VITF-3 subunit protein Asparaginase_2 PF01112.13 AEO59697.1 - 4.1e-81 272.1 0.1 5.1e-81 271.8 0.0 1.0 1 0 0 1 1 1 1 Asparaginase G_glu_transpept PF01019.16 AEO59697.1 - 0.04 12.4 0.0 0.062 11.7 0.0 1.1 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase p450 PF00067.17 AEO59698.1 - 1e-70 238.5 0.0 6.5e-70 235.9 0.0 1.8 2 0 0 2 2 2 1 Cytochrome P450 Pkinase PF00069.20 AEO59699.1 - 1.4e-13 50.5 0.0 3e-13 49.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.18 AEO59699.1 - 2.3e-09 37.3 0.8 3.4e-07 30.2 0.9 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 AEO59699.1 - 1.2e-07 31.0 0.0 2.2e-07 30.2 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO59699.1 - 1.1e-05 24.5 0.0 1.5e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 AEO59699.1 - 0.022 13.8 0.0 0.1 11.6 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 AEO59699.1 - 0.061 12.6 0.0 0.099 11.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family EcKinase PF02958.15 AEO59699.1 - 0.13 11.3 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase Glyco_transf_20 PF00982.16 AEO59700.1 - 9.5e-198 657.4 0.0 1.1e-197 657.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.6 AEO59700.1 - 0.073 12.5 0.1 0.22 10.9 0.0 1.8 2 0 0 2 2 2 0 Starch synthase catalytic domain Tape_meas_lam_C PF09718.5 AEO59700.1 - 0.17 11.8 1.3 0.68 9.8 0.3 2.4 3 0 0 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) MFS_1 PF07690.11 AEO59701.1 - 9.4e-29 100.2 56.0 5.2e-27 94.4 8.7 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Glyco_hydro_67M PF07488.7 AEO59703.1 - 4.4e-148 492.5 0.0 5.5e-148 492.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.7 AEO59703.1 - 5.2e-95 317.1 0.0 8.9e-95 316.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.9 AEO59703.1 - 4.1e-23 81.7 0.0 1.2e-10 41.4 0.0 2.9 3 0 0 3 3 3 2 Glycosyl hydrolase family 67 N-terminus Glyco_hydro_20b PF02838.10 AEO59703.1 - 0.0092 16.5 0.2 0.022 15.2 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 VSP PF03302.8 AEO59705.1 - 0.018 13.6 1.6 0.023 13.3 1.1 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF1183 PF06682.7 AEO59705.1 - 0.039 13.5 0.1 0.084 12.4 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1183) Zip PF02535.17 AEO59705.1 - 0.1 11.6 0.1 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter VID27 PF08553.5 AEO59707.1 - 0 1154.5 0.1 0 1154.3 0.0 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein Nop14 PF04147.7 AEO59707.1 - 0.41 8.5 16.3 0.6 7.9 11.3 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 AEO59707.1 - 2.3 6.1 12.6 3.6 5.5 8.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Prenylcys_lyase PF07156.9 AEO59708.1 - 1.6e-27 96.4 0.0 2.5e-27 95.7 0.0 1.3 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.1 AEO59708.1 - 9.8e-14 51.1 0.0 2.7e-13 49.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 AEO59708.1 - 1.9e-09 37.1 0.0 1.2e-07 31.2 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.19 AEO59708.1 - 3.7e-08 32.6 0.6 1.2e-07 30.9 0.4 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 AEO59708.1 - 8.1e-05 22.7 0.4 0.0075 16.3 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 AEO59708.1 - 0.00012 22.0 0.3 0.017 15.0 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 AEO59708.1 - 0.00027 20.7 0.2 0.005 16.6 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.12 AEO59708.1 - 0.0013 17.9 0.2 0.0065 15.6 0.0 2.0 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 AEO59708.1 - 0.0069 16.7 0.1 0.042 14.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 AEO59708.1 - 0.015 14.1 1.0 0.027 13.3 0.7 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.14 AEO59708.1 - 0.02 13.9 0.1 0.032 13.2 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 AEO59708.1 - 0.044 12.6 0.6 0.069 12.0 0.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 AEO59708.1 - 0.077 12.6 0.5 5.3 6.6 0.1 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Malic_M PF03949.10 AEO59708.1 - 0.17 11.4 1.4 0.2 11.1 0.1 1.8 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain Cpn60_TCP1 PF00118.19 AEO59709.1 - 1.4e-151 505.4 0.1 1.6e-151 505.2 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PDCD2_C PF04194.8 AEO59710.1 - 4.7e-56 188.8 0.0 7.1e-56 188.3 0.0 1.2 1 0 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain PCI_Csn8 PF10075.4 AEO59711.1 - 3.2e-37 127.4 0.0 5.5e-37 126.7 0.0 1.4 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 AEO59711.1 - 1e-22 80.7 0.1 1.4e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DNA_ligase_A_M PF01068.16 AEO59712.1 - 2.4e-51 173.9 0.0 1.2e-48 165.2 0.0 2.1 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.10 AEO59712.1 - 1.8e-18 66.6 0.0 1.2e-17 64.0 0.0 2.4 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region Aldose_epim PF01263.15 AEO59713.1 - 5.5e-58 196.4 0.0 6.6e-58 196.1 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase PAS_5 PF07310.8 AEO59714.1 - 0.057 12.9 0.0 0.066 12.7 0.0 1.1 1 0 0 1 1 1 0 PAS domain Ifi-6-16 PF06140.8 AEO59715.1 - 0.0016 18.2 0.0 0.0035 17.0 0.0 1.6 2 0 0 2 2 2 1 Interferon-induced 6-16 family End3 PF12761.2 AEO59715.1 - 0.055 13.0 0.0 0.075 12.6 0.0 1.2 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Nucleoplasmin PF03066.10 AEO59716.1 - 0.00073 19.0 0.3 0.00073 19.0 0.2 1.1 1 0 0 1 1 1 1 Nucleoplasmin NpwBP PF12622.2 AEO59716.1 - 0.061 13.8 2.6 0.097 13.1 1.8 1.2 1 0 0 1 1 1 0 mRNA biogenesis factor Ribosomal_60s PF00428.14 AEO59716.1 - 0.095 13.1 8.2 0.12 12.7 5.7 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein Myc_N PF01056.13 AEO59716.1 - 0.11 11.5 4.8 0.14 11.3 3.3 1.1 1 0 0 1 1 1 0 Myc amino-terminal region EBV-NA3 PF05009.7 AEO59716.1 - 0.16 11.1 1.9 0.21 10.8 1.3 1.1 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) FAM176 PF14851.1 AEO59716.1 - 0.25 11.0 2.2 0.33 10.6 1.5 1.1 1 0 0 1 1 1 0 FAM176 family Pox_Ag35 PF03286.9 AEO59716.1 - 0.28 10.6 2.0 0.36 10.3 1.4 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PBP1_TM PF14812.1 AEO59716.1 - 0.3 11.4 3.2 0.49 10.7 2.2 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Adeno_terminal PF02459.10 AEO59716.1 - 2.6 6.1 6.3 3.6 5.6 4.3 1.2 1 0 0 1 1 1 0 Adenoviral DNA terminal protein BSP_II PF05432.6 AEO59716.1 - 5.2 6.2 14.1 6.6 5.9 9.8 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Radial_spoke PF04712.7 AEO59716.1 - 6.7 5.3 11.3 8.6 4.9 7.9 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein Pkinase PF00069.20 AEO59718.1 - 2.4e-23 82.6 0.0 4.7e-23 81.6 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO59718.1 - 3.5e-11 42.6 0.0 1.1e-10 41.0 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 AEO59718.1 - 0.039 13.6 0.0 0.083 12.6 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family PBP_GOBP PF01395.17 AEO59718.1 - 0.087 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 PBP/GOBP family AAL_decarboxy PF03306.8 AEO59719.1 - 3.2e-78 261.7 0.7 3.7e-78 261.5 0.5 1.0 1 0 0 1 1 1 1 Alpha-acetolactate decarboxylase HET PF06985.6 AEO59720.1 - 3.7e-25 88.6 0.3 6.1e-25 87.9 0.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF605 PF04652.11 AEO59721.1 - 0.21 10.9 9.7 0.28 10.5 6.7 1.2 1 0 0 1 1 1 0 Vta1 like SR-25 PF10500.4 AEO59721.1 - 1.7 8.0 19.9 0.29 10.5 9.0 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Secretin_N_2 PF07655.8 AEO59721.1 - 1.9 8.9 8.7 15 6.0 0.2 2.4 2 0 0 2 2 2 0 Secretin N-terminal domain KAR9 PF08580.5 AEO59721.1 - 5.1 5.2 9.1 6.1 4.9 6.3 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 FAM220 PF15487.1 AEO59721.1 - 9.7 5.4 7.4 15 4.8 5.1 1.3 1 0 0 1 1 1 0 FAM220 family DUF3767 PF12597.3 AEO59722.1 - 2.6e-40 136.7 0.1 6.1e-40 135.5 0.0 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF3767) DUF1744 PF08490.7 AEO59723.1 - 2.5e-156 520.2 0.0 3.6e-156 519.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 AEO59723.1 - 2.7e-65 220.3 0.3 4.5e-65 219.6 0.2 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 AEO59723.1 - 2.2e-21 76.2 0.0 5.9e-21 74.7 0.0 1.7 1 1 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 AEO59723.1 - 5.3e-09 35.9 0.2 1.3e-08 34.6 0.2 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB zf-CCCH PF00642.19 AEO59724.1 - 5e-06 26.0 17.6 0.00017 21.1 1.9 3.4 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MFS_1 PF07690.11 AEO59725.1 - 2.1e-47 161.5 49.8 2.1e-47 161.5 34.5 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 AEO59725.1 - 3.4e-16 58.5 13.3 3.4e-16 58.5 9.2 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 AEO59725.1 - 2.9e-10 39.3 32.9 8.9e-10 37.7 8.9 2.8 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_3 PF05977.8 AEO59725.1 - 4.2e-05 21.8 10.8 0.0075 14.4 2.2 2.3 2 0 0 2 2 2 2 Transmembrane secretion effector ATG22 PF11700.3 AEO59725.1 - 0.00068 18.2 9.8 0.00068 18.2 6.8 4.1 3 2 1 4 4 4 1 Vacuole effluxer Atg22 like OATP PF03137.15 AEO59725.1 - 0.0056 14.8 0.7 0.0056 14.8 0.5 2.3 3 0 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family DUF829 PF05705.9 AEO59726.1 - 3.6e-20 72.6 0.6 1e-07 31.9 0.0 4.1 3 1 1 4 4 4 4 Eukaryotic protein of unknown function (DUF829) DUF1191 PF06697.7 AEO59727.1 - 0.001 17.9 0.0 0.0013 17.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Adeno_E3_CR2 PF02439.10 AEO59727.1 - 0.032 13.7 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.1 AEO59727.1 - 0.039 14.3 0.0 0.08 13.3 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Planc_extracel PF07595.7 AEO59727.1 - 0.25 11.0 2.1 0.8 9.4 1.5 1.9 1 0 0 1 1 1 0 Planctomycete extracellular Ribosomal_S2 PF00318.15 AEO59728.1 - 3e-49 167.0 0.0 6.9e-49 165.9 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S2 CBS PF00571.23 AEO59728.1 - 5.5e-41 138.0 8.5 3e-10 39.7 0.0 5.7 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 AEO59728.1 - 1.6e-07 30.8 0.0 4e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 PB1 domain zf-H2C2 PF09337.5 AEO59729.1 - 1.3e-22 78.9 4.6 3.1e-22 77.6 3.2 1.7 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Imm47 PF15586.1 AEO59729.1 - 0.04 13.7 0.0 0.099 12.4 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 47 CPSF73-100_C PF11718.3 AEO59729.1 - 0.21 10.8 11.0 0.34 10.2 1.6 2.5 2 0 0 2 2 2 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Cpn60_TCP1 PF00118.19 AEO59730.1 - 3e-143 477.9 3.3 3.5e-143 477.7 2.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ribosomal_S26e PF01283.14 AEO59733.1 - 1.8e-51 173.1 8.9 2.1e-51 172.9 6.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e DUF1918 PF08940.6 AEO59733.1 - 0.026 13.8 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) Zn_ribbon_2 PF12674.2 AEO59733.1 - 0.043 14.1 0.3 7 7.0 0.0 2.2 1 1 1 2 2 2 0 Putative zinc ribbon domain Fer4_7 PF12838.2 AEO59733.1 - 0.074 13.4 2.3 0.87 10.0 0.4 2.3 2 1 0 2 2 2 0 4Fe-4S dicluster domain ubiquitin PF00240.18 AEO59734.1 - 9.4e-34 114.6 0.9 1.9e-33 113.6 0.7 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 AEO59734.1 - 7.5e-20 70.4 0.6 1.5e-19 69.3 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ribosomal_S27 PF01599.14 AEO59734.1 - 2.4e-10 40.0 0.1 5.5e-10 38.9 0.1 1.7 1 0 0 1 1 1 1 Ribosomal protein S27a Ubiquitin_2 PF14560.1 AEO59734.1 - 1.5e-05 25.1 0.6 7.9e-05 22.8 0.1 2.3 2 1 0 2 2 2 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 AEO59734.1 - 0.00018 21.2 0.2 0.00027 20.6 0.1 1.4 1 1 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 AEO59734.1 - 0.0015 18.3 0.5 0.0026 17.6 0.4 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 AEO59734.1 - 0.0058 16.7 0.6 0.0074 16.4 0.4 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 AEO59734.1 - 0.022 14.7 0.5 0.051 13.6 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Plexin_cytopl PF08337.7 AEO59734.1 - 0.23 9.7 2.2 1.1 7.4 0.1 2.0 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain Tash_PEST PF07708.6 AEO59734.1 - 0.34 10.9 1.3 0.59 10.1 0.9 1.4 1 0 0 1 1 1 0 Tash protein PEST motif DUF2207 PF09972.4 AEO59734.1 - 0.36 9.3 3.0 0.41 9.1 2.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Glyco_hydro_18 PF00704.23 AEO59735.1 - 6.7e-97 325.0 0.2 7.6e-97 324.8 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 AP_endonuc_2 PF01261.19 AEO59735.1 - 0.068 12.4 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Polysacc_deac_1 PF01522.16 AEO59736.1 - 1.3e-17 63.5 0.0 2.2e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Pkinase PF00069.20 AEO59737.1 - 2e-63 214.0 0.0 3.2e-63 213.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO59737.1 - 8.3e-30 103.7 0.0 1.5e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 AEO59737.1 - 4.7e-07 29.0 0.0 1e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family NACHT PF05729.7 AEO59737.1 - 2.6e-06 27.1 0.0 7.1e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Kinase-like PF14531.1 AEO59737.1 - 0.00031 19.8 0.0 0.00072 18.6 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 AEO59737.1 - 0.0021 17.8 0.0 0.0083 15.8 0.0 2.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 AEO59737.1 - 0.0036 16.1 0.0 0.0057 15.4 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Annexin PF00191.15 AEO59738.1 - 1.1e-30 105.3 1.4 3.9e-15 55.4 0.0 4.3 4 0 0 4 4 4 4 Annexin DUF883 PF05957.8 AEO59742.1 - 0.057 13.8 9.3 0.077 13.4 1.7 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) LEA_4 PF02987.11 AEO59742.1 - 0.42 10.5 18.9 0.7 9.8 1.8 3.8 2 1 1 3 3 3 0 Late embryogenesis abundant protein CsbD PF05532.7 AEO59742.1 - 1 9.0 24.8 0.077 12.6 10.1 3.6 2 1 1 3 3 3 0 CsbD-like YtxH PF12732.2 AEO59742.1 - 6.4 7.2 12.4 1.8e+03 -0.7 8.6 2.8 1 1 0 1 1 1 0 YtxH-like protein ECH PF00378.15 AEO59743.1 - 1e-45 155.7 0.1 1e-42 145.9 0.0 2.3 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family WSC PF01822.14 AEO59744.1 - 1.9e-11 43.6 9.2 4.6e-11 42.4 6.4 1.7 1 0 0 1 1 1 1 WSC domain SKG6 PF08693.5 AEO59744.1 - 1.7e-06 27.2 2.1 1.7e-06 27.2 1.5 1.8 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF4366 PF14283.1 AEO59744.1 - 3.2e-05 23.4 0.1 0.00033 20.1 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4366) DUF4448 PF14610.1 AEO59744.1 - 0.0024 17.3 0.0 0.0034 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Podoplanin PF05808.6 AEO59744.1 - 0.0028 17.2 1.3 0.0045 16.5 0.9 1.2 1 0 0 1 1 1 1 Podoplanin DUF3042 PF11240.3 AEO59744.1 - 5.6 6.8 6.1 16 5.3 4.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3042) DUF4470 PF14737.1 AEO59745.1 - 2.4e-20 72.1 0.0 6.7e-20 70.6 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 AEO59745.1 - 4.1e-11 42.5 11.9 8.5e-11 41.5 8.2 1.6 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.2 AEO59745.1 - 0.12 11.7 1.8 0.28 10.5 1.2 1.5 1 0 0 1 1 1 0 Life-span regulatory factor zf-H2C2_2 PF13465.1 AEO59746.1 - 1.8e-09 37.4 7.2 0.00027 21.0 0.1 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 AEO59746.1 - 1.2e-08 34.8 18.0 0.00024 21.2 3.7 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AEO59746.1 - 0.014 15.7 16.5 0.82 10.1 0.2 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_6 PF13912.1 AEO59746.1 - 3.1 7.8 7.4 1 9.3 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger adh_short PF00106.20 AEO59747.1 - 8.6e-29 100.5 2.4 1.3e-28 99.9 1.7 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO59747.1 - 1.7e-26 93.4 0.3 2.1e-26 93.1 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO59747.1 - 4.1e-13 49.4 0.9 6e-13 48.8 0.7 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 AEO59747.1 - 2.9e-05 23.6 0.8 0.0023 17.4 0.5 3.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 AEO59747.1 - 0.025 13.5 0.3 0.037 13.0 0.2 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase AdoHcyase_NAD PF00670.16 AEO59747.1 - 0.051 13.4 1.5 0.11 12.2 0.4 1.9 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.13 AEO59747.1 - 0.14 11.7 1.5 0.53 9.9 1.2 1.9 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2536 PF10750.4 AEO59748.1 - 0.086 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2536) MARVEL PF01284.18 AEO59749.1 - 2.3e-05 24.2 8.0 4.1e-05 23.4 5.6 1.5 1 1 0 1 1 1 1 Membrane-associating domain PrgI PF12666.2 AEO59749.1 - 0.38 10.9 0.0 0.38 10.9 0.0 2.6 2 1 0 2 2 2 0 PrgI family protein DUF4233 PF14017.1 AEO59749.1 - 0.83 9.6 9.0 0.081 12.8 1.6 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4233) Tyrosinase PF00264.15 AEO59750.1 - 1.3e-41 143.2 0.0 1.6e-41 142.8 0.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase His_Phos_1 PF00300.17 AEO59755.1 - 1.5e-19 70.6 0.0 1.9e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Rxt3 PF08642.5 AEO59755.1 - 0.033 14.4 0.0 0.053 13.7 0.0 1.3 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 DctQ PF04290.7 AEO59757.1 - 0.06 13.1 0.2 0.06 13.1 0.1 1.8 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component DUF3377 PF11857.3 AEO59757.1 - 0.34 10.5 6.2 1.6 8.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) MpPF26 PF07666.6 AEO59757.1 - 7.3 6.5 8.2 15 5.4 0.2 2.4 2 1 0 2 2 2 0 M penetrans paralogue family 26 Kelch_4 PF13418.1 AEO59758.1 - 1.6e-13 50.1 14.9 0.0088 15.7 0.5 5.9 5 1 0 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.1 AEO59758.1 - 7e-12 45.0 7.6 0.017 15.0 0.0 6.4 6 1 0 6 6 6 3 Kelch motif Kelch_6 PF13964.1 AEO59758.1 - 2.5e-08 33.7 4.4 0.99 9.6 0.0 5.7 5 1 1 6 6 6 3 Kelch motif Kelch_3 PF13415.1 AEO59758.1 - 6.9e-08 32.4 19.8 0.041 14.0 0.0 7.9 7 1 0 7 7 7 2 Galactose oxidase, central domain Kelch_1 PF01344.20 AEO59758.1 - 0.00012 21.5 5.1 0.78 9.3 0.0 4.5 4 1 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 AEO59758.1 - 0.0002 20.9 4.3 0.32 10.8 0.1 4.4 5 0 0 5 5 5 2 Kelch motif PQQ_3 PF13570.1 AEO59758.1 - 0.0021 18.2 2.1 0.2 11.9 0.0 3.5 4 0 0 4 4 4 1 PQQ-like domain DUF1668 PF07893.8 AEO59758.1 - 0.0025 17.0 0.0 0.004 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1668) MFS_1 PF07690.11 AEO59759.1 - 1.5e-20 73.2 50.5 5.2e-18 64.8 34.6 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 AEO59759.1 - 2.1e-06 26.2 24.5 2.1e-06 26.2 17.0 1.7 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF1375 PF07119.7 AEO59759.1 - 0.036 13.8 0.2 0.11 12.3 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1375) DUF948 PF06103.6 AEO59760.1 - 0.025 14.4 2.4 0.026 14.3 0.4 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) IncA PF04156.9 AEO59760.1 - 1 8.8 7.2 0.69 9.4 3.1 1.9 2 0 0 2 2 2 0 IncA protein CorA PF01544.13 AEO59761.1 - 0.0057 15.7 1.4 0.0063 15.5 0.9 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein WD40 PF00400.27 AEO59765.1 - 6.4e-08 32.1 0.1 6.4e-08 32.1 0.1 1.8 2 1 0 2 2 2 1 WD domain, G-beta repeat RecR PF02132.10 AEO59767.1 - 0.0012 18.2 0.5 0.0019 17.6 0.4 1.2 1 0 0 1 1 1 1 RecR protein DZR PF12773.2 AEO59767.1 - 0.0046 16.7 1.9 0.0096 15.7 1.3 1.5 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.1 AEO59767.1 - 0.0065 15.6 6.2 0.059 12.6 4.3 2.2 1 1 1 2 2 2 2 zinc-ribbon domain zinc_ribbon_2 PF13240.1 AEO59767.1 - 0.064 12.7 7.0 0.75 9.3 0.8 2.5 1 1 1 2 2 2 0 zinc-ribbon domain Nudix_N_2 PF14803.1 AEO59767.1 - 0.1 12.3 5.6 2.6 7.7 0.5 2.4 2 0 0 2 2 2 0 Nudix N-terminal Tic20 PF09685.5 AEO59767.1 - 0.12 12.4 4.8 0.75 9.7 3.3 1.9 1 1 1 2 2 2 0 Tic20-like protein zf-NADH-PPase PF09297.6 AEO59767.1 - 0.32 10.5 8.7 1.2 8.6 1.3 2.4 1 1 1 2 2 2 0 NADH pyrophosphatase zinc ribbon domain DUF805 PF05656.9 AEO59767.1 - 1.4 8.7 9.1 24 4.7 6.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF805) DUF1469 PF07332.6 AEO59767.1 - 3.4 7.4 7.6 10 5.8 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) Ank_2 PF12796.2 AEO59768.1 - 4.4e-28 97.4 11.1 8.2e-11 42.1 0.3 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 AEO59768.1 - 6e-18 63.6 8.7 5.7e-08 32.1 0.1 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 AEO59768.1 - 3.9e-16 59.0 6.6 6.9e-06 26.4 0.2 3.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 AEO59768.1 - 9e-15 54.3 11.1 2.3e-07 30.8 0.3 4.4 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 AEO59768.1 - 1.4e-13 49.6 5.0 0.00019 21.3 0.0 4.4 5 0 0 5 5 5 3 Ankyrin repeat Fungal_trans PF04082.13 AEO59770.1 - 5.7e-30 104.0 0.0 1e-29 103.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO59770.1 - 1.5e-08 34.3 7.6 3e-08 33.4 5.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_3 PF13738.1 AEO59771.1 - 3.1e-16 60.0 0.0 9.4e-16 58.4 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 AEO59771.1 - 8.9e-06 24.1 0.0 1.3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 AEO59771.1 - 0.0012 18.8 0.1 0.0036 17.2 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 AEO59771.1 - 0.011 14.6 0.0 0.024 13.5 0.0 1.5 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) CHAT PF12770.2 AEO59772.1 - 2.9e-28 98.8 0.2 5.6e-28 97.8 0.2 1.5 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.1 AEO59772.1 - 6.1e-07 29.2 6.3 0.00047 20.0 0.0 4.9 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 AEO59772.1 - 0.016 15.3 0.8 10 6.6 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 AEO59772.1 - 1.8 8.6 20.5 0.083 12.8 0.3 6.5 7 0 0 7 7 7 0 Tetratricopeptide repeat GMC_oxred_N PF00732.14 AEO59774.1 - 2.9e-46 157.9 1.3 4.5e-46 157.3 0.9 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 AEO59774.1 - 1.5e-28 99.8 0.0 1.8e-27 96.4 0.0 2.3 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 AEO59774.1 - 0.00016 20.6 2.4 0.005 15.8 1.7 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 AEO59774.1 - 0.0045 15.8 2.7 0.007 15.2 1.9 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 AEO59774.1 - 0.0076 16.1 0.4 0.89 9.3 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AEO59774.1 - 0.041 13.9 0.3 0.11 12.5 0.2 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Gluconate_2-dh3 PF13618.1 AEO59774.1 - 0.045 13.9 0.0 9.2 6.4 0.0 2.8 2 1 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 DUF3112 PF11309.3 AEO59775.1 - 0.12 12.1 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) JAB PF01398.16 AEO59776.1 - 1.6e-14 53.6 0.0 2.4e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.6 AEO59776.1 - 5.2e-08 32.8 0.0 1.2e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.1 AEO59776.1 - 1.2e-06 27.9 0.0 3.1e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Prefoldin_2 PF01920.15 AEO59778.1 - 2.5e-23 81.8 15.6 3e-23 81.5 10.8 1.1 1 0 0 1 1 1 1 Prefoldin subunit IncA PF04156.9 AEO59778.1 - 0.00059 19.4 13.2 0.001 18.7 9.1 1.3 1 0 0 1 1 1 1 IncA protein Lzipper-MIP1 PF14389.1 AEO59778.1 - 0.0012 18.9 5.5 0.089 12.9 2.0 2.2 2 0 0 2 2 2 1 Leucine-zipper of ternary complex factor MIP1 Spc24 PF08286.6 AEO59778.1 - 0.0042 16.7 10.2 0.045 13.4 2.7 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 DUF1732 PF08340.6 AEO59778.1 - 0.0083 15.9 2.2 0.085 12.6 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1732) Prefoldin PF02996.12 AEO59778.1 - 0.01 15.4 12.3 0.024 14.2 1.0 2.2 2 0 0 2 2 2 0 Prefoldin subunit DivIC PF04977.10 AEO59778.1 - 0.021 14.2 17.9 0.09 12.2 2.1 3.3 2 2 1 3 3 3 0 Septum formation initiator Tropomyosin_1 PF12718.2 AEO59778.1 - 0.025 14.3 14.5 0.64 9.8 4.9 2.1 2 0 0 2 2 2 0 Tropomyosin like COG5 PF10392.4 AEO59778.1 - 0.028 14.3 3.3 1.3 8.9 0.1 2.1 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DUF4601 PF15373.1 AEO59778.1 - 0.029 13.2 0.0 0.029 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4601) Prefoldin_3 PF13758.1 AEO59778.1 - 0.031 14.0 6.9 0.043 13.5 4.8 1.2 1 0 0 1 1 1 0 Prefoldin subunit Occludin_ELL PF07303.8 AEO59778.1 - 0.046 14.4 7.5 0.047 14.4 1.4 2.1 2 0 0 2 2 2 0 Occludin homology domain DUF4201 PF13870.1 AEO59778.1 - 0.05 13.0 12.7 0.55 9.6 0.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Sugarporin_N PF11471.3 AEO59778.1 - 0.064 12.9 0.2 0.064 12.9 0.1 3.2 1 1 1 2 2 1 0 Maltoporin periplasmic N-terminal extension DUF737 PF05300.6 AEO59778.1 - 0.1 12.5 11.6 0.5 10.3 8.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF737) Sas10_Utp3 PF04000.10 AEO59778.1 - 0.13 12.4 7.1 0.63 10.2 2.5 2.2 2 0 0 2 2 2 0 Sas10/Utp3/C1D family DUF342 PF03961.8 AEO59778.1 - 0.13 10.6 9.1 0.18 10.2 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Cortex-I_coil PF09304.5 AEO59778.1 - 0.14 12.1 13.2 0.79 9.7 3.7 2.1 2 0 0 2 2 2 0 Cortexillin I, coiled coil Nup54 PF13874.1 AEO59778.1 - 0.15 11.7 8.2 1.6 8.3 1.0 2.1 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 NPV_P10 PF05531.7 AEO59778.1 - 0.17 12.1 6.2 0.43 10.8 2.2 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein PHTB1_N PF14727.1 AEO59778.1 - 0.18 10.7 10.0 0.47 9.3 0.8 2.0 2 0 0 2 2 2 0 PTHB1 N-terminus Tho2 PF11262.3 AEO59778.1 - 0.18 10.7 5.9 1.6 7.7 0.4 2.0 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF3584 PF12128.3 AEO59778.1 - 0.29 8.4 11.7 0.3 8.3 8.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Tropomyosin PF00261.15 AEO59778.1 - 0.32 10.0 12.9 5.4 6.0 8.9 2.0 1 1 0 1 1 1 0 Tropomyosin Laminin_I PF06008.9 AEO59778.1 - 0.41 9.9 11.0 0.76 9.0 0.5 2.1 2 0 0 2 2 2 0 Laminin Domain I GAS PF13851.1 AEO59778.1 - 0.42 9.7 15.6 3.6 6.7 10.8 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Mnd1 PF03962.10 AEO59778.1 - 0.55 9.8 13.0 3.3 7.3 9.0 1.9 1 1 0 1 1 1 0 Mnd1 family MutS_IV PF05190.13 AEO59778.1 - 0.75 10.0 5.3 11 6.3 3.2 2.2 1 1 0 1 1 1 0 MutS family domain IV DUF964 PF06133.6 AEO59778.1 - 0.83 9.6 15.5 0.089 12.8 5.1 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF964) DUF4164 PF13747.1 AEO59778.1 - 0.84 9.8 9.7 3 8.0 2.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) FliD_C PF07195.7 AEO59778.1 - 0.91 8.7 5.7 3.1 7.0 3.9 1.8 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Tektin PF03148.9 AEO59778.1 - 1 7.8 9.8 0.93 7.9 1.7 2.0 2 0 0 2 2 2 0 Tektin family Macoilin PF09726.4 AEO59778.1 - 1.1 7.5 14.1 1.8 6.7 9.8 1.4 1 1 0 1 1 1 0 Transmembrane protein ERp29 PF07749.7 AEO59778.1 - 1.3 9.7 8.2 9.3 6.9 5.7 2.1 1 1 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain TPR_MLP1_2 PF07926.7 AEO59778.1 - 1.7 8.3 15.6 13 5.4 10.1 2.3 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF4140 PF13600.1 AEO59778.1 - 1.9 9.0 8.8 5.2 7.5 2.4 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Spc7 PF08317.6 AEO59778.1 - 1.9 7.0 14.3 3.5 6.1 9.9 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein CDC37_N PF03234.9 AEO59778.1 - 2 8.7 9.5 2.7 8.2 6.6 1.2 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Atg14 PF10186.4 AEO59778.1 - 2 7.2 14.5 7.1 5.4 10.0 1.7 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Snapin_Pallidin PF14712.1 AEO59778.1 - 2.2 8.6 10.5 7.2 6.9 0.1 2.3 1 1 1 2 2 2 0 Snapin/Pallidin Fez1 PF06818.10 AEO59778.1 - 2.2 8.2 13.2 0.32 10.9 0.4 2.1 1 1 1 2 2 2 0 Fez1 DUF641 PF04859.7 AEO59778.1 - 2.2 8.0 10.1 2.1 8.0 0.8 2.2 1 1 0 2 2 2 0 Plant protein of unknown function (DUF641) Cep57_MT_bd PF06657.8 AEO59778.1 - 2.5 8.1 12.2 5.4 7.0 0.8 2.9 1 1 2 3 3 3 0 Centrosome microtubule-binding domain of Cep57 BLOC1_2 PF10046.4 AEO59778.1 - 2.7 8.1 10.8 4.1 7.6 0.3 2.5 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 BRE1 PF08647.6 AEO59778.1 - 2.8 7.9 11.6 4.8 7.2 0.4 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Kinesin-relat_1 PF12711.2 AEO59778.1 - 2.9 8.3 10.6 6.9 7.1 2.6 2.2 2 0 0 2 2 2 0 Kinesin motor CENP-H PF05837.7 AEO59778.1 - 3 8.0 8.9 15 5.7 2.7 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF2968 PF11180.3 AEO59778.1 - 3.3 7.0 14.5 2.2 7.6 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) DUF972 PF06156.8 AEO59778.1 - 3.5 8.0 11.1 4.5 7.6 3.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Swi5 PF07061.6 AEO59778.1 - 3.5 7.4 8.8 6.2 6.6 1.7 2.2 2 0 0 2 2 2 0 Swi5 DUF2730 PF10805.3 AEO59778.1 - 4 7.2 6.8 6.6 6.5 0.4 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2730) Ax_dynein_light PF10211.4 AEO59778.1 - 4.1 7.2 14.2 3.4 7.4 1.3 2.1 2 0 0 2 2 2 0 Axonemal dynein light chain DUF724 PF05266.9 AEO59778.1 - 4.7 6.7 15.4 2.6 7.6 3.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF2802 PF10975.3 AEO59778.1 - 5.7 6.7 8.6 12 5.7 2.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2802) DUF848 PF05852.6 AEO59778.1 - 5.8 6.7 9.7 3.8 7.3 1.8 2.1 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Kinetocho_Slk19 PF12709.2 AEO59778.1 - 6.1 7.0 11.2 15 5.7 3.1 2.9 2 1 1 3 3 3 0 Central kinetochore-associated Folliculin PF11704.3 AEO59778.1 - 6.1 6.3 7.8 2.4 7.7 1.0 2.0 1 1 1 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport TMF_TATA_bd PF12325.3 AEO59778.1 - 6.3 6.5 13.8 3 7.6 4.7 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF1192 PF06698.6 AEO59778.1 - 6.5 6.6 10.9 1.8 8.4 0.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) DUF2408 PF10303.4 AEO59778.1 - 7.5 6.6 9.6 25 4.9 6.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) FlaC_arch PF05377.6 AEO59778.1 - 7.8 6.4 7.8 11 5.9 0.4 2.9 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF904 PF06005.7 AEO59778.1 - 9.1 6.6 16.3 58 4.0 11.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF904) COG2 PF06148.6 AEO59778.1 - 9.5 6.0 9.8 12 5.7 2.6 2.1 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 AAA PF00004.24 AEO59779.1 - 5.2e-43 146.4 0.0 1.1e-42 145.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 AEO59779.1 - 1.3e-29 101.8 0.2 2.7e-28 97.6 0.1 2.8 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 AEO59779.1 - 3.2e-21 74.9 4.9 3.2e-21 74.9 3.4 2.5 3 0 0 3 3 2 1 MIT (microtubule interacting and transport) domain AAA_17 PF13207.1 AEO59779.1 - 4.2e-07 30.7 0.2 2.9e-05 24.8 0.0 3.0 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 AEO59779.1 - 4.9e-06 25.7 0.0 1.2e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 AEO59779.1 - 5.9e-06 25.8 0.5 0.15 11.4 0.1 3.8 1 1 2 3 3 3 2 AAA domain AAA_22 PF13401.1 AEO59779.1 - 1.6e-05 25.0 0.1 0.0016 18.5 0.1 2.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 AEO59779.1 - 2.2e-05 23.9 0.0 5.2e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.9 AEO59779.1 - 3.1e-05 23.7 0.0 0.00022 20.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 AEO59779.1 - 3.3e-05 23.8 0.0 7.1e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 AEO59779.1 - 4.6e-05 23.5 0.1 0.011 15.9 0.0 3.0 3 0 0 3 3 2 1 RNA helicase AAA_16 PF13191.1 AEO59779.1 - 7.3e-05 22.8 1.0 0.00076 19.5 0.0 2.6 3 1 1 4 4 2 1 AAA ATPase domain DUF815 PF05673.8 AEO59779.1 - 7.7e-05 21.7 0.0 0.00062 18.7 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF815) TIP49 PF06068.8 AEO59779.1 - 0.00018 20.3 0.0 0.0003 19.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 AEO59779.1 - 0.00021 21.2 0.0 0.00072 19.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 AEO59779.1 - 0.0012 18.7 0.0 0.0051 16.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.7 AEO59779.1 - 0.0043 16.1 0.2 0.17 10.9 0.0 2.8 2 1 1 3 3 3 1 Zeta toxin AAA_24 PF13479.1 AEO59779.1 - 0.0046 16.5 0.0 0.013 15.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AEO59779.1 - 0.0096 16.2 0.1 0.031 14.5 0.0 2.0 2 0 0 2 2 1 1 AAA domain NACHT PF05729.7 AEO59779.1 - 0.011 15.4 0.0 0.35 10.4 0.0 2.6 2 1 1 3 3 2 0 NACHT domain Arch_ATPase PF01637.13 AEO59779.1 - 0.02 14.6 0.1 0.18 11.5 0.0 2.4 2 1 1 3 3 2 0 Archaeal ATPase Mg_chelatase PF01078.16 AEO59779.1 - 0.021 13.9 0.0 0.064 12.4 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ResIII PF04851.10 AEO59779.1 - 0.032 14.0 0.0 0.071 12.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PhoH PF02562.11 AEO59779.1 - 0.039 13.1 0.0 0.096 11.8 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.12 AEO59779.1 - 0.045 12.6 0.0 0.075 11.8 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 KaiC PF06745.8 AEO59779.1 - 0.046 12.8 0.1 6.1 5.8 0.0 3.1 2 1 1 3 3 3 0 KaiC Torsin PF06309.6 AEO59779.1 - 0.052 13.4 0.1 0.13 12.1 0.0 1.6 2 0 0 2 2 1 0 Torsin AAA_19 PF13245.1 AEO59779.1 - 0.063 13.0 0.0 0.063 13.0 0.0 2.2 2 0 0 2 2 1 0 Part of AAA domain AAA_21 PF13304.1 AEO59779.1 - 0.074 13.0 0.2 3.3 7.5 0.0 2.3 1 1 1 2 2 2 0 AAA domain AAA_28 PF13521.1 AEO59779.1 - 0.095 12.6 0.0 0.31 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain Guanylate_kin PF00625.16 AEO59779.1 - 0.11 11.8 0.0 0.41 10.0 0.0 2.0 1 0 0 1 1 1 0 Guanylate kinase Peptidase_M28 PF04389.12 AEO59779.1 - 0.12 12.1 0.0 0.63 9.7 0.0 2.0 2 0 0 2 2 2 0 Peptidase family M28 ABC_tran PF00005.22 AEO59779.1 - 0.12 12.6 0.1 1.8 8.8 0.0 2.8 3 1 0 3 3 3 0 ABC transporter CPT PF07931.7 AEO59779.1 - 0.12 11.9 0.1 0.56 9.8 0.0 2.0 2 1 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Sigma54_activat PF00158.21 AEO59779.1 - 0.14 11.6 0.8 0.38 10.2 0.0 2.2 2 1 0 2 2 1 0 Sigma-54 interaction domain Nop PF01798.13 AEO59780.1 - 5.1e-55 184.8 0.1 8.6e-55 184.1 0.0 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 AEO59780.1 - 1.4e-22 79.2 0.0 3.2e-22 78.0 0.0 1.7 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 AEO59780.1 - 1.1e-19 70.3 0.0 1.1e-19 70.3 0.0 2.3 2 0 0 2 2 2 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.6 AEO59780.1 - 0.068 12.8 26.7 0.11 12.0 18.5 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 GAGA_bind PF06217.7 AEO59780.1 - 0.35 10.8 10.4 0.57 10.0 7.2 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family CDC45 PF02724.9 AEO59780.1 - 6.8 4.5 15.3 10 4.0 10.6 1.2 1 0 0 1 1 1 0 CDC45-like protein YqfQ PF14181.1 AEO59780.1 - 9.6 6.2 12.8 24 4.9 8.9 1.7 1 0 0 1 1 1 0 YqfQ-like protein zf-C2H2_4 PF13894.1 AEO59781.1 - 3.9e-05 23.6 22.6 0.22 11.9 1.4 5.7 4 1 1 5 5 5 4 C2H2-type zinc finger zf-met2 PF12907.2 AEO59781.1 - 0.38 10.7 5.1 3.4 7.7 0.1 3.1 2 1 0 2 2 2 0 Zinc-binding DUF629 PF04780.7 AEO59781.1 - 0.58 8.6 5.2 0.3 9.5 0.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF629) zf-C2H2 PF00096.21 AEO59781.1 - 2.4 8.6 22.7 4.6 7.7 0.2 5.4 5 1 0 5 5 5 0 Zinc finger, C2H2 type Nudix_N_2 PF14803.1 AEO59781.1 - 7.3 6.3 10.7 0.25 11.0 0.1 2.9 3 0 0 3 3 3 0 Nudix N-terminal DUF1996 PF09362.5 AEO59782.1 - 2.9e-91 305.3 0.6 2.9e-91 305.3 0.4 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) Peptidase_C70 PF12385.3 AEO59782.1 - 0.44 10.2 0.0 0.44 10.2 0.0 3.1 3 1 0 3 3 3 0 Papain-like cysteine protease AvrRpt2 DUF3633 PF12315.3 AEO59782.1 - 5.4 6.2 5.4 8.3 5.6 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3633) FAM70 PF14967.1 AEO59782.1 - 6.3 5.9 8.7 9.7 5.2 6.0 1.3 1 0 0 1 1 1 0 FAM70 protein Pkinase PF00069.20 AEO59783.1 - 8.6e-07 28.3 0.0 1.2e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 AEO59783.1 - 5.6e-06 25.5 0.0 1.1e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AEO59783.1 - 1.9e-05 24.5 4.1 3.4e-05 23.7 0.1 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 AEO59783.1 - 0.00011 21.8 0.0 0.00021 20.9 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF3762 PF12591.3 AEO59784.1 - 0.19 11.7 0.7 1.9 8.5 0.8 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3762) RVT_1 PF00078.22 AEO59785.1 - 4e-05 23.0 0.4 4.3e-05 22.9 0.2 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CENP-F_leu_zip PF10473.4 AEO59786.1 - 0.067 13.0 1.4 0.079 12.8 1.0 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pox_A_type_inc PF04508.7 AEO59786.1 - 0.14 12.0 0.7 0.14 12.0 0.5 1.8 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF3619 PF12279.3 AEO59786.1 - 0.23 11.5 1.7 0.32 11.0 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) Mto2_bdg PF12808.2 AEO59786.1 - 0.28 11.3 6.8 0.42 10.7 4.7 1.2 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region CBM_19 PF03427.8 AEO59789.1 - 0.00015 21.4 2.4 0.00015 21.4 1.6 2.6 2 1 0 2 2 2 2 Carbohydrate binding domain (family 19) ADIP PF11559.3 AEO59791.1 - 0.00024 21.0 6.4 0.21 11.4 2.1 2.2 2 0 0 2 2 2 2 Afadin- and alpha -actinin-Binding HOOK PF05622.7 AEO59791.1 - 0.0053 14.6 8.2 0.094 10.5 0.1 2.0 2 0 0 2 2 2 2 HOOK protein CENP-F_leu_zip PF10473.4 AEO59791.1 - 0.0069 16.2 8.2 0.019 14.8 1.0 2.2 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF972 PF06156.8 AEO59791.1 - 0.008 16.5 2.8 0.61 10.4 0.6 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF972) Nup54 PF13874.1 AEO59791.1 - 0.0084 15.7 5.2 0.91 9.1 1.5 2.2 2 0 0 2 2 2 2 Nucleoporin complex subunit 54 TBPIP PF07106.8 AEO59791.1 - 0.0096 15.4 5.0 0.91 9.0 1.3 2.1 2 0 0 2 2 2 2 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) GOLGA2L5 PF15070.1 AEO59791.1 - 0.0097 14.4 3.3 0.51 8.7 0.0 2.0 2 0 0 2 2 2 2 Putative golgin subfamily A member 2-like protein 5 GCOM2 PF15328.1 AEO59791.1 - 0.011 15.4 1.3 0.18 11.4 0.5 2.0 2 0 0 2 2 2 0 Putative GRINL1B complex locus protein 2 IncA PF04156.9 AEO59791.1 - 0.031 13.8 6.8 1.4 8.4 0.1 2.1 2 0 0 2 2 2 0 IncA protein DASH_Dad2 PF08654.5 AEO59791.1 - 0.033 14.1 2.8 0.53 10.3 0.1 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad2 Mnd1 PF03962.10 AEO59791.1 - 0.048 13.3 6.8 1.4 8.5 2.1 2.1 2 0 0 2 2 2 0 Mnd1 family TMF_TATA_bd PF12325.3 AEO59791.1 - 0.05 13.3 6.4 0.25 11.0 0.1 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Spc24 PF08286.6 AEO59791.1 - 0.056 13.1 5.5 0.98 9.1 0.0 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 APG6 PF04111.7 AEO59791.1 - 0.063 12.3 4.9 0.6 9.1 1.3 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 MerR_2 PF13591.1 AEO59791.1 - 0.064 12.8 1.2 0.064 12.8 0.8 2.4 2 0 0 2 2 2 0 MerR HTH family regulatory protein AKNA PF12443.3 AEO59791.1 - 0.067 13.2 3.6 3.1 7.8 0.1 2.3 2 0 0 2 2 2 0 AT-hook-containing transcription factor ATG16 PF08614.6 AEO59791.1 - 0.071 12.9 8.2 0.69 9.6 0.3 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) CDC37_N PF03234.9 AEO59791.1 - 0.074 13.3 4.3 0.7 10.1 0.9 2.1 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding DUF3373 PF11853.3 AEO59791.1 - 0.086 11.3 2.5 0.11 11.0 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3373) 5_3_exonuc PF01367.15 AEO59791.1 - 0.12 12.6 1.2 0.64 10.2 0.4 2.0 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Spc7 PF08317.6 AEO59791.1 - 0.12 10.9 6.7 1.8 7.1 0.1 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein DivIC PF04977.10 AEO59791.1 - 0.14 11.6 11.9 0.44 10.0 4.3 2.2 2 0 0 2 2 2 0 Septum formation initiator SlyX PF04102.7 AEO59791.1 - 0.14 12.5 10.2 2.7 8.4 0.1 2.3 2 0 0 2 2 2 0 SlyX DUF2203 PF09969.4 AEO59791.1 - 0.15 12.3 1.4 5.1 7.3 0.5 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Viral_P18 PF04521.8 AEO59791.1 - 0.34 10.3 5.5 2.3 7.7 0.1 2.2 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein DUF2802 PF10975.3 AEO59791.1 - 0.4 10.4 6.2 0.57 9.9 1.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) Ax_dynein_light PF10211.4 AEO59791.1 - 0.4 10.4 6.6 0.73 9.6 1.3 2.1 2 0 0 2 2 2 0 Axonemal dynein light chain DUF4140 PF13600.1 AEO59791.1 - 0.48 10.8 7.1 0.54 10.7 1.3 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Atg14 PF10186.4 AEO59791.1 - 0.64 8.9 3.7 4.3 6.2 1.0 2.0 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Prefoldin_2 PF01920.15 AEO59791.1 - 1.5 8.6 11.4 1.8 8.3 3.6 2.4 2 0 0 2 2 2 0 Prefoldin subunit Seryl_tRNA_N PF02403.17 AEO59791.1 - 1.5 8.8 6.9 3.1 7.8 1.1 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DivIVA PF05103.8 AEO59791.1 - 1.5 8.8 8.8 6.3 6.8 0.1 2.1 2 0 0 2 2 2 0 DivIVA protein Striatin PF08232.7 AEO59791.1 - 1.6 9.0 8.4 5.8 7.2 1.3 2.2 2 0 0 2 2 2 0 Striatin family FlxA PF14282.1 AEO59791.1 - 1.8 8.5 8.9 2.1 8.3 4.5 2.0 2 0 0 2 2 2 0 FlxA-like protein Ead_Ea22 PF13935.1 AEO59791.1 - 2.2 8.6 9.3 1.1e+02 3.1 6.4 2.3 1 1 0 1 1 1 0 Ead/Ea22-like protein XhlA PF10779.4 AEO59791.1 - 2.3 8.1 8.4 6.8 6.6 1.3 2.3 2 0 0 2 2 2 0 Haemolysin XhlA DUF4446 PF14584.1 AEO59791.1 - 2.5 7.9 4.6 9.3 6.0 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) DUF3847 PF12958.2 AEO59791.1 - 2.7 7.7 13.7 1.6 8.5 3.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) COMP PF11598.3 AEO59791.1 - 4.5 7.4 6.0 12 6.0 0.4 2.4 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein PspB PF06667.7 AEO59791.1 - 4.8 7.1 6.5 15 5.5 0.4 2.4 2 0 0 2 2 2 0 Phage shock protein B bZIP_1 PF00170.16 AEO59791.1 - 7.7 6.5 9.6 10 6.1 0.6 2.8 2 2 1 3 3 3 0 bZIP transcription factor DUF4407 PF14362.1 AEO59791.1 - 8.7 5.2 8.7 10 5.0 3.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) MerR_2 PF13591.1 AEO59792.1 - 0.075 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 MerR HTH family regulatory protein DUF1993 PF09351.5 AEO59793.1 - 8e-22 77.8 0.0 1.4e-21 77.0 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1993) DUF1479 PF07350.7 AEO59794.1 - 1.8e-152 507.6 0.0 2.3e-152 507.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.8 AEO59794.1 - 0.0013 18.8 0.1 0.14 12.1 0.1 2.3 2 0 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) Fungal_trans PF04082.13 AEO59795.1 - 1.9e-06 26.9 0.4 3.2e-06 26.2 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DEAD PF00270.24 AEO59796.1 - 2.5e-42 144.2 0.0 2.5e-42 144.2 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO59796.1 - 2.3e-23 81.8 0.1 2.3e-23 81.8 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Nucleoporin2 PF04096.9 AEO59796.1 - 0.0027 17.5 0.7 0.0062 16.3 0.5 1.5 1 0 0 1 1 1 1 Nucleoporin autopeptidase PAT1 PF09770.4 AEO59796.1 - 0.13 10.4 23.3 0.2 9.8 16.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Suf PF05843.9 AEO59796.1 - 0.41 10.3 7.3 0.68 9.6 5.1 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) CMS1 PF14617.1 AEO59796.1 - 0.6 9.1 0.0 0.6 9.1 0.0 2.3 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit DnaJ PF00226.26 AEO59797.1 - 3e-12 46.0 0.3 5.5e-12 45.2 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain Phage_GP20 PF06810.6 AEO59799.1 - 0.011 15.2 2.7 0.011 15.2 1.9 2.7 4 0 0 4 4 4 0 Phage minor structural protein GP20 DUF2031 PF09592.5 AEO59799.1 - 0.077 12.1 0.1 0.13 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) OmpH PF03938.9 AEO59799.1 - 0.15 11.9 9.4 0.57 10.0 0.9 3.1 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) YlqD PF11068.3 AEO59799.1 - 0.17 11.9 5.7 14 5.6 0.8 3.3 3 0 0 3 3 3 0 YlqD protein ATG16 PF08614.6 AEO59799.1 - 0.19 11.5 18.1 0.13 12.0 4.9 3.3 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) Borrelia_P83 PF05262.6 AEO59799.1 - 0.19 9.9 2.4 0.28 9.4 1.7 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Spc7 PF08317.6 AEO59799.1 - 0.27 9.8 12.5 0.028 13.0 2.4 2.5 3 0 0 3 3 3 0 Spc7 kinetochore protein Spc42p PF11544.3 AEO59799.1 - 0.28 11.1 3.0 3.9 7.4 0.1 2.8 2 0 0 2 2 2 0 Spindle pole body component Spc42p DUF342 PF03961.8 AEO59799.1 - 0.31 9.3 1.7 14 3.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF342) DUF641 PF04859.7 AEO59799.1 - 0.38 10.5 12.5 2.3 7.9 1.6 3.5 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) DivIC PF04977.10 AEO59799.1 - 0.42 10.1 20.7 0.61 9.6 1.7 5.2 5 2 1 6 6 6 0 Septum formation initiator TMF_TATA_bd PF12325.3 AEO59799.1 - 0.53 10.0 18.6 0.8 9.4 1.2 3.0 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding V_ATPase_I PF01496.14 AEO59799.1 - 0.87 7.3 3.2 9.8 3.8 0.0 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Bap31 PF05529.7 AEO59799.1 - 0.96 8.8 4.9 0.32 10.4 0.9 2.1 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like TBPIP PF07106.8 AEO59799.1 - 3.9 7.0 11.4 1.3 8.5 2.5 2.8 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CCDC-167 PF15188.1 AEO59799.1 - 9.4 6.2 12.0 15 5.5 2.3 3.5 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 F-box-like_2 PF13013.1 AEO59800.1 - 0.11 12.2 0.6 0.32 10.7 0.2 1.9 1 1 1 2 2 2 0 F-box-like domain ALIX_LYPXL_bnd PF13949.1 AEO59801.1 - 9.9e-05 21.4 11.9 0.00018 20.5 8.3 1.5 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Syntaxin PF00804.20 AEO59801.1 - 0.0006 19.9 6.3 0.0006 19.9 4.3 3.0 1 1 1 3 3 3 1 Syntaxin CENP-F_leu_zip PF10473.4 AEO59801.1 - 0.012 15.5 13.4 1 9.2 0.2 3.3 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Seryl_tRNA_N PF02403.17 AEO59801.1 - 0.014 15.3 12.0 1.5 8.8 1.7 3.9 3 1 0 3 3 2 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.7 AEO59801.1 - 0.015 15.0 1.3 0.015 15.0 0.9 2.7 3 0 0 3 3 2 0 Protein of unknown function (DUF1664) Pox_A_type_inc PF04508.7 AEO59801.1 - 0.054 13.2 1.1 0.59 10.0 0.1 2.8 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat M60-like PF13402.1 AEO59801.1 - 0.077 11.8 0.1 0.12 11.2 0.1 1.3 1 0 0 1 1 1 0 Peptidase M60-like family Bacillus_HBL PF05791.6 AEO59801.1 - 0.094 12.0 11.4 0.99 8.7 3.8 2.9 2 1 2 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) AAA_13 PF13166.1 AEO59801.1 - 0.14 10.5 8.7 0.046 12.1 1.0 1.9 1 1 1 2 2 2 0 AAA domain APG6 PF04111.7 AEO59801.1 - 0.16 10.9 11.5 0.055 12.5 0.7 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 Hemerythrin PF01814.18 AEO59801.1 - 0.18 11.9 1.2 0.69 10.0 0.8 2.1 1 1 0 1 1 1 0 Hemerythrin HHE cation binding domain ATG16 PF08614.6 AEO59801.1 - 0.26 11.0 18.9 0.12 12.1 9.9 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF972 PF06156.8 AEO59801.1 - 0.3 11.4 12.1 3.8 7.8 0.1 3.5 3 1 0 3 3 2 0 Protein of unknown function (DUF972) HrpB7 PF09486.5 AEO59801.1 - 0.31 10.9 12.2 2 8.3 0.0 2.6 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF342 PF03961.8 AEO59801.1 - 0.34 9.2 8.7 0.79 8.0 2.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF342) LXG PF04740.7 AEO59801.1 - 0.54 10.0 11.0 8 6.1 0.1 3.7 2 1 2 4 4 4 0 LXG domain of WXG superfamily IncA PF04156.9 AEO59801.1 - 0.55 9.7 16.5 2.3 7.7 0.1 2.4 1 1 0 2 2 2 0 IncA protein DUF4446 PF14584.1 AEO59801.1 - 0.59 9.9 7.2 2 8.2 1.4 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4446) DUF4559 PF15112.1 AEO59801.1 - 0.63 9.1 5.3 1 8.4 3.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) HAUS-augmin3 PF14932.1 AEO59801.1 - 0.64 9.1 14.0 3.4 6.7 0.1 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 TBPIP PF07106.8 AEO59801.1 - 0.69 9.4 13.3 1 8.8 3.2 2.8 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Fmp27_WPPW PF10359.4 AEO59801.1 - 0.72 8.2 11.7 3.1 6.0 0.1 2.4 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Reo_sigmaC PF04582.7 AEO59801.1 - 0.84 8.7 11.6 0.28 10.3 3.3 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF948 PF06103.6 AEO59801.1 - 1.1 9.1 8.0 8.7 6.2 0.1 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.6 AEO59801.1 - 1.3 7.5 14.4 0.05 12.2 1.2 2.3 2 1 1 3 3 2 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.7 AEO59801.1 - 1.4 8.7 16.1 3.7 7.3 0.8 2.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 AEO59801.1 - 1.9 8.7 13.5 13 6.0 3.3 4.2 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein RmuC PF02646.11 AEO59801.1 - 2.8 6.6 14.3 0.25 10.1 0.5 3.4 1 1 2 3 3 3 0 RmuC family V_ATPase_I PF01496.14 AEO59801.1 - 3 5.5 6.9 3.4 5.4 1.4 1.9 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Filament PF00038.16 AEO59801.1 - 3 7.2 15.7 40 3.5 9.7 2.6 1 1 0 1 1 1 0 Intermediate filament protein DUF2408 PF10303.4 AEO59801.1 - 3.8 7.6 10.2 32 4.6 4.3 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) HeLo PF14479.1 AEO59801.1 - 4 7.1 12.5 1.1 8.9 6.1 1.9 1 1 1 2 2 2 0 Prion-inhibition and propagation TMCO5 PF14992.1 AEO59801.1 - 4.3 6.3 9.6 1.4 7.9 2.4 1.9 1 1 2 3 3 3 0 TMCO5 family Allexi_40kDa PF05549.6 AEO59801.1 - 6.1 6.0 14.0 1.6 7.9 5.3 2.3 1 1 1 2 2 2 0 Allexivirus 40kDa protein Spc24 PF08286.6 AEO59801.1 - 6.2 6.5 14.4 15 5.3 0.6 3.9 2 1 2 4 4 4 0 Spc24 subunit of Ndc80 GAS PF13851.1 AEO59801.1 - 6.8 5.8 14.7 6.2 5.9 4.6 2.8 2 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding COG2 PF06148.6 AEO59801.1 - 7.1 6.4 12.7 0.16 11.8 0.5 3.1 3 1 0 3 3 2 0 COG (conserved oligomeric Golgi) complex component, COG2 MscS_porin PF12795.2 AEO59801.1 - 8.4 5.6 32.4 0.38 10.0 1.7 2.7 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain Cupin_2 PF07883.6 AEO59802.1 - 6.5e-08 31.9 0.1 2.1e-07 30.3 0.0 1.9 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.7 AEO59802.1 - 0.0012 18.1 0.0 0.0024 17.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) AraC_binding PF02311.14 AEO59802.1 - 0.012 15.2 0.0 0.027 14.1 0.0 1.6 2 0 0 2 2 2 0 AraC-like ligand binding domain DUF3506 PF12014.3 AEO59803.1 - 5.2e-43 146.1 0.0 8.5e-43 145.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3506) F-box-like PF12937.2 AEO59803.1 - 4e-10 39.2 0.2 6.8e-10 38.5 0.1 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 AEO59803.1 - 8.5e-07 28.4 0.1 1.7e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.6 AEO59803.1 - 0.13 12.6 0.0 0.24 11.7 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Period_C PF12114.3 AEO59803.1 - 1 8.9 5.4 1.8 8.1 3.7 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Serglycin PF04360.7 AEO59803.1 - 1.1 8.9 13.0 6.1 6.5 9.1 1.9 1 1 0 1 1 1 0 Serglycin Oxidored_molyb PF00174.14 AEO59804.1 - 5.1e-53 178.9 0.0 7.8e-53 178.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 AEO59804.1 - 1.4e-26 92.6 0.0 2.2e-16 59.6 0.0 3.2 3 0 0 3 3 3 2 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.23 AEO59804.1 - 2.3e-14 52.9 0.0 4.2e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain BNR PF02012.15 AEO59804.1 - 0.38 10.7 5.6 1 9.4 0.1 3.1 2 0 0 2 2 2 0 BNR/Asp-box repeat DUF1561 PF07598.6 AEO59805.1 - 0.16 9.8 0.0 0.25 9.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1561) DZR PF12773.2 AEO59805.1 - 2.7 7.8 19.6 5.8 6.8 0.5 3.9 2 1 2 4 4 4 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 AEO59805.1 - 3.1 7.4 11.1 3.7 7.1 0.1 3.7 3 0 0 3 3 3 0 zinc-ribbon domain Transaldolase PF00923.14 AEO59806.1 - 2e-48 165.0 0.0 2.6e-48 164.6 0.0 1.1 1 0 0 1 1 1 1 Transaldolase DUF2564 PF10819.3 AEO59806.1 - 0.052 13.6 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2564) TcpA PF05946.7 AEO59806.1 - 0.1 12.4 0.1 0.56 10.0 0.0 2.0 2 0 0 2 2 2 0 Toxin-coregulated pilus subunit TcpA UbiA PF01040.13 AEO59807.1 - 2.2e-31 109.0 24.8 3.2e-31 108.4 17.2 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family Myb_DNA-bind_6 PF13921.1 AEO59808.1 - 5.5e-07 29.6 0.8 7.1e-06 26.0 0.1 2.3 1 1 1 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 AEO59808.1 - 0.006 16.6 0.2 0.017 15.1 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain V4R PF02830.13 AEO59808.1 - 1.2 9.0 4.2 6.1 6.7 0.0 3.5 3 1 0 3 3 3 0 V4R domain Sugar_tr PF00083.19 AEO59809.1 - 5.3e-112 374.6 28.5 7.6e-112 374.1 19.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO59809.1 - 6.1e-26 90.9 56.2 4.8e-24 84.7 21.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 AEO59809.1 - 0.007 14.8 37.2 0.026 12.9 8.8 3.0 3 1 0 3 3 3 2 MFS/sugar transport protein Lysis_S PF04971.7 AEO59809.1 - 0.12 12.0 1.3 0.34 10.6 0.2 2.3 2 0 0 2 2 2 0 Lysis protein S Kinesin PF00225.18 AEO59810.1 - 4e-84 282.1 0.9 6.2e-84 281.5 0.6 1.3 1 0 0 1 1 1 1 Kinesin motor domain Herpes_UL14 PF03580.9 AEO59810.1 - 0.013 15.3 3.4 0.027 14.2 2.3 1.5 1 0 0 1 1 1 0 Herpesvirus UL14-like protein zf-C2H2 PF00096.21 AEO59812.1 - 2.2e-06 27.6 3.4 0.0073 16.5 0.1 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AEO59812.1 - 0.00011 22.2 2.0 0.016 15.5 0.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 AEO59812.1 - 0.0081 16.2 2.1 3 8.0 0.1 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding LIM PF00412.17 AEO59812.1 - 0.074 13.1 1.3 0.17 11.9 0.9 1.6 1 1 0 1 1 1 0 LIM domain zf-Di19 PF05605.7 AEO59812.1 - 0.19 11.8 2.0 3.9 7.6 0.7 2.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 AEO59812.1 - 0.61 10.0 3.1 4.4 7.3 0.0 2.3 1 1 1 2 2 2 0 C2H2-type zinc finger Glyco_hydro_62 PF03664.8 AEO59813.1 - 5.7e-141 468.3 6.8 6.5e-141 468.1 4.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 HRXXH PF13933.1 AEO59816.1 - 9.8e-105 349.4 0.0 1.2e-104 349.1 0.0 1.0 1 0 0 1 1 1 1 Putative peptidase family APH PF01636.18 AEO59817.1 - 3.5e-16 59.6 0.0 6.3e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 AEO59817.1 - 0.02 14.5 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase NmrA PF05368.8 AEO59818.1 - 2.1e-31 109.0 0.0 2.2e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 AEO59818.1 - 1.2e-13 51.5 4.1 3.2e-13 50.0 2.2 1.9 1 1 1 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 AEO59818.1 - 0.0031 16.9 1.1 0.0047 16.4 0.8 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 AEO59818.1 - 0.0034 16.1 0.2 0.0074 15.0 0.2 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 AEO59818.1 - 0.014 15.8 0.8 0.045 14.1 0.5 2.0 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.20 AEO59818.1 - 0.028 14.3 5.8 0.056 13.3 4.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase KIP1 PF07765.7 AEO59818.1 - 0.041 13.7 0.0 0.07 12.9 0.0 1.3 1 0 0 1 1 1 0 KIP1-like protein Saccharop_dh PF03435.13 AEO59818.1 - 0.067 12.1 1.0 0.092 11.6 0.7 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase RmlD_sub_bind PF04321.12 AEO59818.1 - 0.13 11.1 0.7 0.21 10.4 0.5 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain DapB_N PF01113.15 AEO59818.1 - 0.16 11.9 1.6 0.28 11.0 1.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus mRNA_triPase PF02940.10 AEO59819.1 - 4.5e-59 199.7 0.0 6.6e-59 199.2 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain PC_rep PF01851.17 AEO59820.1 - 3.9e-37 124.4 22.3 8.8e-09 35.1 0.0 9.8 11 0 0 11 11 11 7 Proteasome/cyclosome repeat HEAT_2 PF13646.1 AEO59820.1 - 7.1e-19 67.8 0.5 3.3e-12 46.5 0.0 5.9 4 1 2 6 6 6 3 HEAT repeats HEAT PF02985.17 AEO59820.1 - 5.8e-09 35.2 0.1 0.84 9.8 0.0 6.5 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 AEO59820.1 - 3.8e-08 33.5 1.5 5.8e-05 23.4 0.0 4.8 4 1 0 4 4 4 1 HEAT-like repeat DUF966 PF06136.8 AEO59820.1 - 0.085 12.2 0.4 1.6 8.0 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF966) DUF1769 PF08588.5 AEO59821.1 - 3.5e-27 94.1 0.3 8.2e-27 92.9 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) MCLC PF05934.6 AEO59821.1 - 0.079 11.2 0.1 0.12 10.6 0.1 1.2 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) MFS_1 PF07690.11 AEO59822.1 - 2.4e-28 98.8 42.6 6.4e-26 90.9 17.9 2.9 2 2 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 AEO59822.1 - 1.5e-07 30.0 3.6 2.7e-07 29.1 2.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_61 PF03443.9 AEO59823.1 - 5.8e-46 157.0 0.0 6.6e-46 156.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 ABC_membrane PF00664.18 AEO59824.1 - 3.3e-60 203.8 24.8 1.3e-34 119.8 5.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 AEO59824.1 - 9.9e-52 174.8 0.0 1.3e-24 87.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 AEO59824.1 - 1e-17 65.0 0.0 0.00015 21.8 0.0 4.2 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 AEO59824.1 - 2.5e-15 56.3 0.0 0.00029 20.1 0.0 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 AEO59824.1 - 8.2e-09 35.7 0.1 0.054 13.4 0.0 4.0 3 1 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.1 AEO59824.1 - 5.7e-08 32.1 0.1 0.015 14.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 AEO59824.1 - 1.7e-07 31.4 0.0 0.31 11.1 0.0 4.0 3 1 0 3 3 3 2 AAA domain AAA_25 PF13481.1 AEO59824.1 - 1.1e-06 28.2 0.0 0.49 9.7 0.0 3.8 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 AEO59824.1 - 3e-06 28.0 0.0 0.24 12.2 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_10 PF12846.2 AEO59824.1 - 3.8e-06 26.5 3.1 0.49 9.7 0.3 4.2 3 1 1 4 4 4 2 AAA-like domain DUF258 PF03193.11 AEO59824.1 - 1e-05 24.7 0.0 0.023 13.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 AEO59824.1 - 0.00021 21.6 0.1 0.25 11.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 AEO59824.1 - 0.00066 19.5 0.0 0.022 14.6 0.0 3.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 AEO59824.1 - 0.00084 19.6 0.0 2.4 8.4 0.0 3.0 3 0 0 3 3 2 2 AAA domain DUF87 PF01935.12 AEO59824.1 - 0.0016 18.3 0.5 0.53 10.0 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 Miro PF08477.8 AEO59824.1 - 0.0042 17.5 0.0 0.57 10.6 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein DUF3987 PF13148.1 AEO59824.1 - 0.0075 14.8 0.0 1.9 6.9 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) AAA_33 PF13671.1 AEO59824.1 - 0.011 15.6 0.0 5.8 6.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 AEO59824.1 - 0.012 15.3 0.0 3 7.5 0.0 3.2 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.13 AEO59824.1 - 0.03 13.7 0.0 3.2 7.1 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 AEO59824.1 - 0.032 14.1 0.0 6 6.8 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.7 AEO59824.1 - 0.035 13.7 0.2 20 4.7 0.1 3.3 3 0 0 3 3 3 0 NACHT domain MobB PF03205.9 AEO59824.1 - 0.052 13.2 0.3 11 5.7 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 AEO59824.1 - 0.054 13.3 0.0 3.5 7.5 0.0 3.3 4 0 0 4 4 3 0 AAA domain AAA_15 PF13175.1 AEO59824.1 - 0.075 12.0 0.0 13 4.7 0.0 3.0 4 0 0 4 4 4 0 AAA ATPase domain RNA_helicase PF00910.17 AEO59824.1 - 0.086 13.0 0.0 8.1 6.6 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_13 PF13166.1 AEO59824.1 - 0.23 9.8 0.0 16 3.7 0.0 2.7 3 0 0 3 3 3 0 AAA domain Polysacc_synt_4 PF04669.8 AEO59825.1 - 9.3e-27 93.6 1.3 4.6e-26 91.3 0.9 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis Elongin_A PF06881.6 AEO59825.1 - 0.0059 16.9 1.1 0.0059 16.9 0.8 1.6 2 1 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Peroxin-22 PF12827.2 AEO59825.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Peroxisomal biogenesis protein family DUF566 PF04484.7 AEO59826.1 - 1.5 8.2 10.0 2.2 7.7 7.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Glyco_hydro_114 PF03537.8 AEO59827.1 - 1.4e-09 37.5 0.0 2.8e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Tannase PF07519.6 AEO59828.1 - 2.7e-16 59.3 0.1 3.9e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 AEO59829.1 - 3.1e-21 76.2 3.0 4.7e-21 75.7 2.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO59829.1 - 3.6e-11 43.0 0.0 9e-11 41.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO59829.1 - 1.4e-05 24.7 0.0 0.063 12.8 0.0 3.0 3 0 0 3 3 3 2 alpha/beta hydrolase fold UPF0227 PF05728.7 AEO59829.1 - 0.011 15.4 0.0 3.2 7.4 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Abhydrolase_4 PF08386.5 AEO59829.1 - 0.033 14.0 0.0 0.071 13.0 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Serglycin PF04360.7 AEO59829.1 - 0.053 13.2 0.0 0.08 12.6 0.0 1.2 1 0 0 1 1 1 0 Serglycin DGC PF08859.6 AEO59829.1 - 0.079 12.8 0.2 0.14 12.0 0.2 1.3 1 0 0 1 1 1 0 DGC domain Thioesterase PF00975.15 AEO59829.1 - 0.094 12.9 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain PLRV_ORF5 PF01690.12 AEO59829.1 - 3.8 6.5 4.7 5.7 5.9 3.2 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein NMT_C PF02799.10 AEO59830.1 - 5.3e-79 264.0 0.0 7.4e-79 263.5 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.14 AEO59830.1 - 5.2e-68 227.7 0.0 8.4e-68 227.0 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.1 AEO59830.1 - 8.8e-07 28.8 0.1 1.4e-05 24.9 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 AEO59830.1 - 0.0064 16.6 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 AEO59830.1 - 0.023 14.8 0.1 0.076 13.1 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF4604 PF15377.1 AEO59830.1 - 5.5 7.1 16.4 11 6.2 11.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Abhydrolase_6 PF12697.2 AEO59832.1 - 4.1e-15 56.2 9.6 8.2e-15 55.3 6.7 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO59832.1 - 2.7e-12 46.6 0.2 4.1e-12 46.0 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO59832.1 - 4.9e-08 32.8 0.1 1e-07 31.7 0.1 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 AEO59832.1 - 3.2e-05 23.5 0.1 4.8e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF218 PF02698.12 AEO59832.1 - 0.0061 16.0 0.0 0.018 14.5 0.0 1.9 1 1 0 1 1 1 1 DUF218 domain Abhydrolase_2 PF02230.11 AEO59832.1 - 0.0061 16.0 0.0 0.013 14.9 0.0 1.5 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Ser_hydrolase PF06821.8 AEO59832.1 - 0.021 14.4 0.1 0.039 13.5 0.1 1.4 1 0 0 1 1 1 0 Serine hydrolase Lipase_3 PF01764.20 AEO59832.1 - 0.024 14.2 0.3 0.048 13.2 0.2 1.4 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.8 AEO59832.1 - 0.097 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Lipase PF00151.14 AEO59832.1 - 0.1 11.7 0.1 0.16 11.1 0.1 1.1 1 0 0 1 1 1 0 Lipase Glyco_hydro_28 PF00295.12 AEO59834.1 - 6e-55 186.4 1.1 8.6e-55 185.9 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 CTD PF12815.2 AEO59835.1 - 6.6e-26 91.1 70.4 2.1e-18 66.8 29.8 5.6 3 1 3 6 6 6 3 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5-NGN PF03439.8 AEO59835.1 - 1.4e-23 82.4 0.0 2.4e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 AEO59835.1 - 1e-17 64.5 10.5 1e-17 64.5 7.2 4.5 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 AEO59835.1 - 0.00052 19.6 20.0 0.0047 16.5 1.5 5.2 6 0 0 6 6 6 2 KOW motif SAPS PF04499.10 AEO59835.1 - 3.5 6.1 9.4 6.3 5.3 6.5 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Glyco_hydro_61 PF03443.9 AEO59836.1 - 4.8e-53 180.1 0.2 5.7e-53 179.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Fimbrial_PilY2 PF14481.1 AEO59836.1 - 0.066 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Type 4 fimbrial biogenesis protein PilY2 DUF2562 PF10814.3 AEO59837.1 - 0.17 11.8 5.0 1.5 8.8 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2562) Pkinase PF00069.20 AEO59839.1 - 3.3e-45 154.2 0.0 8e-45 153.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO59839.1 - 1.6e-31 109.3 0.0 2.3e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 AEO59839.1 - 0.0021 17.1 0.0 0.054 12.5 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 AEO59839.1 - 0.1 11.5 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Fungal_trans PF04082.13 AEO59842.1 - 5e-19 68.2 0.0 8.4e-19 67.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ribosomal_L19e PF01280.15 AEO59843.1 - 0.15 11.8 0.9 0.23 11.2 0.6 1.3 1 0 0 1 1 1 0 Ribosomal protein L19e NAD_binding_10 PF13460.1 AEO59844.1 - 1.4e-18 67.5 0.2 4.1e-18 66.0 0.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 AEO59844.1 - 0.0008 18.9 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PK PF00224.16 AEO59845.1 - 2e-120 401.6 1.2 3.2e-120 400.9 0.8 1.3 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 AEO59845.1 - 1.6e-30 105.0 0.0 3.9e-30 103.8 0.0 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 AEO59845.1 - 8.2e-05 21.5 0.7 0.00021 20.2 0.4 1.7 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.16 AEO59846.1 - 4.7e-41 140.5 0.2 5.3e-41 140.3 0.1 1.0 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain IMPDH PF00478.20 AEO59846.1 - 0.012 14.5 0.0 0.015 14.2 0.0 1.1 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain DUF1748 PF08520.5 AEO59847.1 - 2.8e-35 119.7 0.2 3.1e-35 119.6 0.1 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) ADH_N PF08240.7 AEO59849.1 - 3e-05 23.7 0.3 0.0001 22.0 0.0 2.0 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AEO59849.1 - 0.013 15.0 0.6 0.033 13.7 0.4 1.8 1 0 0 1 1 1 0 Zinc-binding dehydrogenase WD40 PF00400.27 AEO59850.1 - 6.3e-33 111.4 8.3 6.6e-10 38.4 0.0 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat Cornichon PF03311.9 AEO59851.1 - 2.3e-54 182.9 10.8 2.6e-54 182.7 7.5 1.0 1 0 0 1 1 1 1 Cornichon protein Peptidase_M24 PF00557.19 AEO59852.1 - 1.3e-46 158.8 0.2 1.6e-46 158.5 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 AEO59852.1 - 7.4e-06 25.7 5.7 1.8e-05 24.4 3.9 1.7 1 0 0 1 1 1 1 MYND finger ATP-cone PF03477.11 AEO59852.1 - 0.085 13.2 0.1 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 ATP cone domain zf-HIT PF04438.11 AEO59852.1 - 0.88 9.2 6.3 2 8.1 4.4 1.7 1 0 0 1 1 1 0 HIT zinc finger FAD_binding_3 PF01494.14 AEO59853.1 - 3.2e-18 65.9 0.0 8e-18 64.6 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 AEO59853.1 - 1e-05 25.8 0.0 8.9e-05 22.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AEO59853.1 - 0.00045 20.1 0.1 0.0012 18.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 AEO59853.1 - 0.0006 18.8 0.0 0.0022 16.9 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 AEO59853.1 - 0.0019 16.7 0.0 0.0028 16.1 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein SE PF08491.5 AEO59853.1 - 0.0022 16.8 0.1 0.005 15.6 0.0 1.7 2 0 0 2 2 2 1 Squalene epoxidase GIDA PF01134.17 AEO59853.1 - 0.0061 15.4 0.0 0.01 14.7 0.0 1.4 1 1 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 AEO59853.1 - 0.0061 16.4 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 AEO59853.1 - 0.021 13.8 0.2 0.076 12.0 0.1 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 AEO59853.1 - 0.1 12.2 0.0 0.38 10.4 0.0 1.9 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 AEO59853.1 - 0.14 11.7 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NMT1 PF09084.6 AEO59856.1 - 2.5e-76 256.0 0.0 3.4e-76 255.6 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 AEO59856.1 - 8.2e-09 35.2 0.6 0.006 15.9 0.1 3.5 2 1 2 4 4 4 3 NMT1-like family Pro_CA PF00484.14 AEO59857.1 - 1.4e-50 171.2 0.0 1.8e-50 170.9 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase AAA PF00004.24 AEO59858.1 - 0.035 14.2 0.1 0.091 12.9 0.0 1.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 AEO59860.1 - 4.9e-41 140.2 0.0 2.1e-20 73.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 AEO59860.1 - 2.2e-34 119.1 21.5 6.8e-22 78.1 7.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 AEO59860.1 - 3.1e-09 37.2 0.2 0.34 10.8 0.0 5.1 4 1 0 4 4 4 2 AAA domain SMC_N PF02463.14 AEO59860.1 - 3.4e-08 32.9 2.6 0.0033 16.6 0.0 4.1 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 AEO59860.1 - 5.7e-08 32.9 2.0 0.0001 22.3 0.0 3.0 3 0 0 3 3 2 2 AAA ATPase domain AAA_29 PF13555.1 AEO59860.1 - 9e-08 31.5 1.5 0.006 16.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SE PF00437.15 AEO59860.1 - 6.9e-07 28.4 0.3 0.0058 15.5 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_33 PF13671.1 AEO59860.1 - 2.3e-06 27.5 0.0 0.00077 19.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 AEO59860.1 - 5e-06 26.6 0.0 0.09 12.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 AEO59860.1 - 2.9e-05 24.8 0.0 0.32 11.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 AEO59860.1 - 3.2e-05 24.2 0.0 0.47 10.7 0.0 3.1 3 0 0 3 3 3 2 AAA domain Miro PF08477.8 AEO59860.1 - 4.1e-05 24.0 0.0 0.042 14.3 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein AAA_23 PF13476.1 AEO59860.1 - 5.2e-05 23.6 2.0 0.076 13.3 0.2 2.3 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 AEO59860.1 - 7.3e-05 21.9 0.9 0.2 10.7 0.0 3.2 3 0 0 3 3 3 2 Zeta toxin AAA_25 PF13481.1 AEO59860.1 - 8e-05 22.1 0.6 0.52 9.6 0.0 2.9 3 0 0 3 3 2 2 AAA domain Dynamin_N PF00350.18 AEO59860.1 - 0.00035 20.4 0.0 0.55 10.0 0.0 2.4 2 0 0 2 2 2 2 Dynamin family FtsK_SpoIIIE PF01580.13 AEO59860.1 - 0.00038 19.9 0.4 0.032 13.7 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family UPF0079 PF02367.12 AEO59860.1 - 0.00042 19.9 0.8 0.059 13.0 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 DUF258 PF03193.11 AEO59860.1 - 0.00052 19.2 1.5 0.48 9.5 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 AEO59860.1 - 0.00064 19.6 0.0 1.1 9.2 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase Arch_ATPase PF01637.13 AEO59860.1 - 0.00088 19.0 0.1 0.99 9.0 0.0 3.1 3 0 0 3 3 3 1 Archaeal ATPase cobW PF02492.14 AEO59860.1 - 0.0016 17.9 0.3 0.051 13.0 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.24 AEO59860.1 - 0.0021 18.2 0.0 0.48 10.6 0.0 3.5 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 AEO59860.1 - 0.0031 17.6 0.0 1.3 9.2 0.0 2.7 3 0 0 3 3 2 1 RNA helicase NACHT PF05729.7 AEO59860.1 - 0.0036 16.9 0.4 0.19 11.3 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_10 PF12846.2 AEO59860.1 - 0.0038 16.7 2.8 0.78 9.1 0.1 3.2 3 0 0 3 3 3 1 AAA-like domain AAA_14 PF13173.1 AEO59860.1 - 0.0047 16.8 0.0 3.6 7.5 0.0 3.2 3 0 0 3 3 3 1 AAA domain NTPase_1 PF03266.10 AEO59860.1 - 0.0072 16.0 0.1 1.3 8.7 0.0 2.4 2 0 0 2 2 2 1 NTPase TrwB_AAD_bind PF10412.4 AEO59860.1 - 0.016 13.8 0.3 2.5 6.6 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain MobB PF03205.9 AEO59860.1 - 0.021 14.5 0.2 6.6 6.4 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PIF1 PF05970.9 AEO59860.1 - 0.022 13.7 0.0 0.16 10.9 0.0 2.1 2 0 0 2 2 2 0 PIF1-like helicase DUF815 PF05673.8 AEO59860.1 - 0.041 12.8 0.3 4.6 6.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_19 PF13245.1 AEO59860.1 - 0.051 13.3 0.1 0.051 13.3 0.1 3.6 4 0 0 4 4 4 0 Part of AAA domain Sigma54_activat PF00158.21 AEO59860.1 - 0.069 12.6 0.1 2 7.8 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Viral_helicase1 PF01443.13 AEO59860.1 - 0.092 12.2 0.0 6.5 6.2 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Adeno_IVa2 PF02456.10 AEO59860.1 - 0.12 10.9 0.3 1.7 7.2 0.1 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_5 PF07728.9 AEO59860.1 - 0.16 11.6 0.6 5.2 6.7 0.0 3.0 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Pox_A32 PF04665.7 AEO59860.1 - 0.22 10.8 0.6 1.1 8.4 0.1 2.0 2 0 0 2 2 2 0 Poxvirus A32 protein ATP_bind_1 PF03029.12 AEO59860.1 - 0.26 10.7 0.1 20 4.6 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF87 PF01935.12 AEO59860.1 - 0.35 10.6 1.4 2.7 7.7 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 APH PF01636.18 AEO59861.1 - 9.6e-05 22.2 0.0 0.00018 21.3 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family BTB PF00651.26 AEO59864.1 - 3.9e-09 36.4 0.2 6.1e-05 22.9 0.0 3.4 1 1 2 3 3 3 2 BTB/POZ domain Fasciclin PF02469.17 AEO59865.1 - 2.9e-31 108.1 0.0 2.5e-23 82.4 0.0 2.5 2 1 0 2 2 2 2 Fasciclin domain Diphthamide_syn PF01866.12 AEO59866.1 - 3.1e-48 164.5 0.0 5.3e-48 163.8 0.0 1.3 1 1 0 1 1 1 1 Putative diphthamide synthesis protein DUF2890 PF11081.3 AEO59866.1 - 0.34 10.9 4.4 0.61 10.1 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) MFS_1 PF07690.11 AEO59867.1 - 6.3e-33 113.9 63.8 6.4e-24 84.3 21.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO59867.1 - 5.3e-13 48.3 35.3 3.8e-09 35.6 8.9 2.8 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_2 PF13347.1 AEO59867.1 - 1.1e-08 33.8 10.0 1.1e-08 33.8 7.0 2.1 1 1 1 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.2 AEO59867.1 - 0.0052 16.5 3.7 0.11 12.3 0.3 2.9 3 0 0 3 3 3 2 MFS_1 like family NHL PF01436.16 AEO59868.1 - 6.8e-06 25.7 0.0 0.11 12.5 0.0 4.1 3 1 1 4 4 4 2 NHL repeat GSDH PF07995.6 AEO59868.1 - 5.1e-05 22.5 0.3 0.087 11.8 0.1 3.2 2 1 0 2 2 2 2 Glucose / Sorbosone dehydrogenase SGL PF08450.7 AEO59868.1 - 0.00032 20.1 0.0 0.0098 15.2 0.0 2.7 2 1 1 3 3 3 1 SMP-30/Gluconolaconase/LRE-like region Lactonase PF10282.4 AEO59868.1 - 0.0075 15.3 0.1 0.042 12.9 0.1 2.0 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SBBP PF06739.6 AEO59868.1 - 0.0088 15.8 0.4 10 6.0 0.0 3.6 4 0 0 4 4 4 2 Beta-propeller repeat MutS_V PF00488.16 AEO59871.1 - 3.3e-81 272.1 0.0 6.7e-81 271.1 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 AEO59871.1 - 5.9e-50 169.8 0.1 1.1e-49 168.9 0.0 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 AEO59871.1 - 1.1e-33 115.6 0.0 2.4e-33 114.5 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 AEO59871.1 - 1.2e-15 57.8 0.0 4e-15 56.0 0.0 2.0 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 AEO59871.1 - 6.5e-14 51.8 0.6 1.6e-13 50.5 0.4 1.7 1 0 0 1 1 1 1 MutS family domain IV AAA_23 PF13476.1 AEO59871.1 - 0.00048 20.5 1.2 0.003 17.9 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 AEO59871.1 - 0.015 14.8 0.0 0.032 13.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.1 AEO59871.1 - 0.037 14.0 1.3 0.081 12.8 0.2 2.1 2 0 0 2 2 2 0 AAA domain Fungal_trans PF04082.13 AEO59872.1 - 0.0012 17.8 0.0 0.0032 16.3 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Mito_carr PF00153.22 AEO59873.1 - 6.6e-41 137.9 3.4 1.7e-14 53.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PT-VENN PF04829.8 AEO59873.1 - 0.26 10.8 1.5 1.6 8.3 0.1 2.5 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif CoA_trans PF01144.18 AEO59875.1 - 3.2e-96 320.6 1.1 4.2e-57 192.8 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 AEO59875.1 - 0.00013 21.6 0.2 0.00026 20.7 0.2 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain MFS_1 PF07690.11 AEO59876.1 - 2.3e-32 112.0 23.2 2.3e-32 112.0 16.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 AEO59876.1 - 0.00015 21.2 2.1 0.00048 19.6 1.5 1.8 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 DUF4048 PF13257.1 AEO59877.1 - 0.057 13.0 2.4 0.097 12.3 1.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4048) AA_permease PF00324.16 AEO59878.1 - 2.8e-101 339.2 40.5 3.2e-101 339.0 28.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AEO59878.1 - 2.2e-26 92.3 43.9 3.3e-26 91.8 30.2 1.4 1 1 0 1 1 1 1 Amino acid permease DUF3129 PF11327.3 AEO59879.1 - 2e-55 187.4 11.4 4.5e-55 186.3 7.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) Abhydrolase_6 PF12697.2 AEO59880.1 - 2.1e-27 96.4 0.2 2.7e-27 96.1 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO59880.1 - 1.6e-10 40.9 0.1 2.7e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 AEO59880.1 - 0.0008 19.0 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 AEO59880.1 - 0.036 13.3 0.0 0.06 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_8 PF06259.7 AEO59880.1 - 0.051 13.0 0.0 0.082 12.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Abhydrolase_1 PF00561.15 AEO59880.1 - 0.062 12.8 0.1 0.25 10.8 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold PE-PPE PF08237.6 AEO59880.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain DUF900 PF05990.7 AEO59880.1 - 0.17 11.1 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF2419 PF10343.4 AEO59880.1 - 0.19 10.9 0.0 0.27 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2419) NACHT PF05729.7 AEO59881.1 - 4.5e-06 26.4 0.0 4.7e-06 26.3 0.0 1.0 1 0 0 1 1 1 1 NACHT domain DUF605 PF04652.11 AEO59882.1 - 2.8 7.2 10.3 3.3 7.0 7.2 1.1 1 0 0 1 1 1 0 Vta1 like MARVEL PF01284.18 AEO59883.1 - 0.045 13.5 14.8 0.061 13.1 10.2 1.2 1 0 0 1 1 1 0 Membrane-associating domain 7TMR-DISM_7TM PF07695.6 AEO59883.1 - 0.049 13.3 18.0 0.26 10.9 9.2 2.1 2 0 0 2 2 2 0 7TM diverse intracellular signalling UNC-50 PF05216.8 AEO59883.1 - 0.066 12.4 3.6 0.039 13.1 1.0 1.6 2 0 0 2 2 2 0 UNC-50 family DUF3149 PF11346.3 AEO59883.1 - 0.076 12.5 2.3 3.2 7.4 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) DUF4293 PF14126.1 AEO59883.1 - 0.18 11.7 3.9 0.13 12.1 0.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) HemY_N PF07219.8 AEO59883.1 - 0.38 10.3 2.6 6.7 6.3 1.0 2.5 2 0 0 2 2 2 0 HemY protein N-terminus UPF0182 PF03699.8 AEO59883.1 - 5 4.9 5.4 3.1 5.6 2.8 1.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0182) SIM_C PF06621.7 AEO59884.1 - 0.11 12.0 0.1 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Single-minded protein C-terminus Xan_ur_permease PF00860.15 AEO59885.1 - 2.6e-66 223.6 30.8 3.9e-65 219.8 21.3 2.0 1 1 0 1 1 1 1 Permease family Redoxin PF08534.5 AEO59886.1 - 2.7e-18 65.8 0.0 9.2e-11 41.4 0.0 2.1 1 1 1 2 2 2 2 Redoxin DUF167 PF02594.11 AEO59887.1 - 2.2e-18 65.9 0.4 2.8e-18 65.6 0.3 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 GRIP PF01465.15 AEO59887.1 - 0.1 12.0 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 GRIP domain DASH_Dam1 PF08653.5 AEO59888.1 - 4.6e-28 96.7 1.1 6.3e-28 96.3 0.7 1.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 CRAL_TRIO PF00650.15 AEO59889.1 - 9.6e-44 148.6 0.1 1.8e-43 147.7 0.1 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 AEO59889.1 - 6.9e-13 48.5 1.8 9.9e-13 48.0 0.0 2.2 3 0 0 3 3 3 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 AEO59889.1 - 4.3e-11 42.9 0.0 7.6e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain HIT PF01230.18 AEO59890.1 - 1.1e-22 80.3 0.0 1.8e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 AEO59890.1 - 1e-12 48.2 0.1 3.1e-12 46.7 0.0 1.7 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 AEO59890.1 - 0.00094 18.8 0.1 0.0015 18.1 0.1 1.4 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Mog1 PF04603.7 AEO59891.1 - 1.3e-16 60.8 0.0 1.8e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Ran-interacting Mog1 protein SprT-like PF10263.4 AEO59892.1 - 2.3e-51 173.5 5.5 3.5e-51 172.9 3.8 1.3 1 0 0 1 1 1 1 SprT-like family HMG_box PF00505.14 AEO59892.1 - 0.0018 18.4 0.2 0.0018 18.4 0.2 2.4 3 0 0 3 3 3 1 HMG (high mobility group) box YABBY PF04690.8 AEO59892.1 - 0.0059 16.8 0.3 0.018 15.2 0.2 1.8 1 0 0 1 1 1 1 YABBY protein PKI PF02827.11 AEO59892.1 - 0.071 13.2 1.6 0.15 12.1 0.1 2.3 2 0 0 2 2 2 0 cAMP-dependent protein kinase inhibitor Zn-ribbon_8 PF09723.5 AEO59892.1 - 0.5 10.3 3.0 1.2 9.1 2.1 1.6 1 0 0 1 1 1 0 Zinc ribbon domain Glucan_synthase PF02364.10 AEO59893.1 - 0 1463.2 0.0 0 1462.7 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 AEO59893.1 - 1.4e-40 137.8 0.5 3.2e-40 136.6 0.3 1.7 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Aminotran_1_2 PF00155.16 AEO59894.1 - 3.5e-36 124.9 0.0 4.3e-36 124.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 AEO59894.1 - 0.0002 19.7 0.0 0.00032 19.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme CoA_trans PF01144.18 AEO59895.1 - 1.7e-98 328.1 0.7 1.5e-57 194.2 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase IBR PF01485.16 AEO59896.1 - 5.3e-22 77.4 45.6 4.3e-12 45.7 4.4 4.5 3 1 1 4 4 4 2 IBR domain zf-C3HC4 PF00097.20 AEO59896.1 - 5.1e-06 26.0 42.0 0.0002 20.9 3.5 4.6 3 1 1 4 4 4 3 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AEO59896.1 - 1.4e-05 25.0 7.8 1.4e-05 25.0 5.4 4.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AEO59896.1 - 4.9e-05 23.0 43.5 0.00062 19.5 5.1 3.6 2 1 1 3 3 3 3 Ring finger domain zf-C3HC4_4 PF15227.1 AEO59896.1 - 1.7 8.5 34.9 0.27 11.1 2.3 4.5 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 AEO59896.1 - 1.8 8.3 45.1 0.033 13.9 5.7 3.8 3 1 0 3 3 3 0 zinc-RING finger domain zf-RING_UBOX PF13445.1 AEO59896.1 - 8.5 6.1 26.3 0.095 12.4 1.9 3.8 3 1 0 3 3 3 0 RING-type zinc-finger FHA PF00498.21 AEO59897.1 - 1e-15 57.5 0.0 1.9e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 FHA domain MIP-T3 PF10243.4 AEO59897.1 - 4.2 5.7 36.8 6 5.2 25.5 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 AAA_16 PF13191.1 AEO59898.1 - 1.1e-06 28.7 0.5 5.5e-06 26.4 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain DUF676 PF05057.9 AEO59898.1 - 4.2e-05 22.9 0.0 7.7e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 AEO59898.1 - 0.0015 18.1 0.0 0.0028 17.2 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Trns_repr_metal PF02583.12 AEO59898.1 - 0.22 11.7 0.0 0.51 10.5 0.0 1.5 1 0 0 1 1 1 0 Metal-sensitive transcriptional repressor VHS PF00790.14 AEO59899.1 - 4e-45 152.9 0.0 1.5e-44 151.0 0.0 2.0 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 AEO59899.1 - 2.4e-24 85.1 0.4 6.7e-24 83.7 0.3 1.8 1 0 0 1 1 1 1 GAT domain Alpha_adaptinC2 PF02883.15 AEO59899.1 - 1.7e-17 63.8 0.1 1.7e-17 63.8 0.0 2.8 4 0 0 4 4 4 1 Adaptin C-terminal domain Coatamer_beta_C PF07718.7 AEO59899.1 - 0.13 11.9 0.0 0.36 10.4 0.0 1.7 1 0 0 1 1 1 0 Coatomer beta C-terminal region DUF367 PF04034.8 AEO59900.1 - 1.4e-46 157.1 0.0 2e-46 156.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 AEO59900.1 - 1.7e-11 43.4 0.6 3e-11 42.7 0.4 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI GTP_EFTU PF00009.22 AEO59901.1 - 2e-40 138.2 2.5 1.4e-39 135.4 1.7 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 AEO59901.1 - 1.2e-25 89.5 1.6 2.5e-25 88.4 1.1 1.6 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 AEO59901.1 - 8.7e-13 48.1 2.1 2.6e-07 30.6 0.1 2.9 2 1 0 2 2 2 2 Elongation factor Tu domain 2 IF2_N PF04760.10 AEO59901.1 - 8.1e-09 35.0 0.0 1.6e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region MMR_HSR1 PF01926.18 AEO59901.1 - 9.1e-08 32.0 0.1 2.6e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 AEO59901.1 - 1.1e-06 29.1 0.1 2.7e-06 27.8 0.1 1.8 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AEO59901.1 - 1.3e-05 24.4 0.0 2.5e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.4 AEO59901.1 - 1.9e-05 24.1 0.2 4.4e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 AEO59901.1 - 0.00016 20.9 0.2 0.00032 19.9 0.1 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.5 AEO59901.1 - 0.0022 17.2 0.0 0.0055 15.9 0.0 1.6 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU_D4 PF14578.1 AEO59901.1 - 0.8 9.3 5.5 0.48 10.1 1.2 2.3 2 0 0 2 2 2 0 Elongation factor Tu domain 4 eIF2A PF08662.6 AEO59904.1 - 3.5e-79 265.0 0.0 2.3e-78 262.3 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 AEO59904.1 - 6.6e-05 22.6 2.4 1.2 9.1 0.1 4.4 3 1 0 3 3 3 2 WD domain, G-beta repeat CDV3 PF15359.1 AEO59904.1 - 0.021 14.8 0.5 0.021 14.8 0.3 2.6 2 1 1 3 3 3 0 Carnitine deficiency-associated protein 3 CP2 PF04516.10 AEO59906.1 - 1.1e-85 286.4 0.0 1.6e-85 285.9 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor Phage_G PF02306.10 AEO59906.1 - 0.014 15.0 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 Major spike protein (G protein) Tektin PF03148.9 AEO59906.1 - 0.13 10.7 0.0 0.22 10.0 0.0 1.2 1 0 0 1 1 1 0 Tektin family Oxysterol_BP PF01237.13 AEO59907.1 - 1.3e-55 188.3 0.0 1.2e-44 152.2 0.0 2.3 2 1 0 2 2 2 2 Oxysterol-binding protein GPP34 PF05719.6 AEO59908.1 - 1.7e-65 220.9 0.1 2.1e-65 220.6 0.1 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) eIF-4B PF06273.6 AEO59908.1 - 1.3 7.7 5.5 1.8 7.2 3.8 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B SURF6 PF04935.7 AEO59909.1 - 4.5e-48 163.3 46.2 4.5e-48 163.3 32.0 4.6 2 1 2 4 4 4 1 Surfeit locus protein 6 RRP14 PF15459.1 AEO59909.1 - 4.3e-21 74.7 0.9 4.3e-21 74.7 0.6 7.6 6 2 0 6 6 6 1 60S ribosome biogenesis protein Rrp14 XPG_I PF00867.13 AEO59910.1 - 4.3e-25 87.5 0.0 7.9e-25 86.7 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 AEO59910.1 - 6.1e-24 84.2 0.0 1.2e-23 83.2 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 AEO59910.1 - 0.00081 18.9 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.15 AEO59910.1 - 0.012 15.7 0.0 0.042 14.0 0.0 1.8 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF2962 PF11176.3 AEO59911.1 - 1.5e-44 151.2 7.0 1.7e-44 151.1 4.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) PIN_4 PF13638.1 AEO59911.1 - 1.1 9.4 3.3 1.5 8.8 2.3 1.5 1 1 0 1 1 1 0 PIN domain RRP7 PF12923.2 AEO59911.1 - 5.3 7.0 12.1 3.1 7.8 0.5 2.6 2 1 1 3 3 3 0 Ribosomal RNA-processing protein 7 (RRP7) Dickkopf_N PF04706.7 AEO59912.1 - 2.8 8.1 8.3 0.83 9.8 0.4 2.3 2 1 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region Laminin_EGF PF00053.19 AEO59912.1 - 5.2 7.0 9.0 1.7 8.6 2.2 2.2 1 1 1 2 2 2 0 Laminin EGF-like (Domains III and V) zf-C3HC4_3 PF13920.1 AEO59912.1 - 8.7 6.0 7.0 12 5.6 0.5 2.3 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) MAM33 PF02330.11 AEO59913.1 - 1.2e-30 106.7 0.6 5.1e-30 104.7 0.4 1.8 1 1 0 1 1 1 1 Mitochondrial glycoprotein Hormone_2 PF00123.15 AEO59913.1 - 0.093 12.5 0.3 0.3 10.9 0.1 2.0 2 0 0 2 2 2 0 Peptide hormone Luteo_Vpg PF01659.11 AEO59913.1 - 0.48 10.1 4.3 0.75 9.5 3.0 1.3 1 0 0 1 1 1 0 Luteovirus putative VPg genome linked protein Thi4 PF01946.12 AEO59914.1 - 3.6e-104 346.8 0.0 4.4e-104 346.6 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 AEO59914.1 - 1.1e-08 34.4 0.1 5.4e-07 28.8 0.5 2.1 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AEO59914.1 - 1.2e-05 25.1 0.9 3.1e-05 23.8 0.7 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 AEO59914.1 - 5.3e-05 22.3 0.3 0.00019 20.4 0.1 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 AEO59914.1 - 0.00035 20.3 2.0 0.00041 20.1 0.1 2.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 AEO59914.1 - 0.0004 20.3 0.1 0.00059 19.7 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 AEO59914.1 - 0.00053 18.9 1.0 0.0032 16.3 0.3 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 AEO59914.1 - 0.0012 19.0 0.1 0.0018 18.3 0.1 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 AEO59914.1 - 0.018 13.5 0.3 0.026 12.9 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 AEO59914.1 - 0.029 14.7 0.4 0.12 12.8 0.2 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 AEO59914.1 - 0.04 12.9 0.0 0.07 12.1 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.9 AEO59914.1 - 0.05 12.2 0.2 0.069 11.7 0.1 1.1 1 0 0 1 1 1 0 Tryptophan halogenase Pyridoxal_deC PF00282.14 AEO59915.1 - 2e-72 243.7 0.0 1.1e-63 214.9 0.0 2.3 3 0 0 3 3 3 2 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 AEO59915.1 - 0.002 17.3 0.0 0.0024 17.0 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 AEO59915.1 - 0.012 14.3 0.0 0.019 13.6 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V SLA_LP_auto_ag PF05889.8 AEO59915.1 - 0.16 10.4 0.0 0.24 9.8 0.0 1.2 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Ras PF00071.17 AEO59916.1 - 6.7e-39 132.8 0.0 1.3e-24 86.3 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 AEO59916.1 - 6.8e-12 45.9 0.0 2.4e-11 44.1 0.0 1.8 1 1 1 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 AEO59916.1 - 0.0079 16.1 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 AEO59916.1 - 0.017 14.4 0.0 0.062 12.5 0.0 1.7 2 0 0 2 2 2 0 ADP-ribosylation factor family Gtr1_RagA PF04670.7 AEO59916.1 - 0.052 12.6 0.0 0.093 11.8 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PRK PF00485.13 AEO59916.1 - 0.059 12.9 1.5 0.12 11.9 0.0 2.0 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family GTP_EFTU PF00009.22 AEO59916.1 - 0.075 12.4 0.0 2.3 7.6 0.0 2.8 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AMMECR1 PF01871.12 AEO59917.1 - 3.1e-45 153.3 0.0 2e-44 150.7 0.0 1.9 2 0 0 2 2 2 1 AMMECR1 SR-25 PF10500.4 AEO59917.1 - 0.085 12.3 10.0 0.13 11.7 6.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 AEO59917.1 - 0.71 9.9 9.3 1.1 9.2 6.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) FAP PF07174.6 AEO59918.1 - 0.12 11.6 1.6 0.12 11.6 1.1 1.0 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) HAD_2 PF13419.1 AEO59921.1 - 5.9e-24 85.2 0.2 9.4e-23 81.3 0.1 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 AEO59921.1 - 0.00064 19.3 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Spore_YhaL PF14147.1 AEO59922.1 - 0.5 9.8 2.1 5 6.6 0.0 2.4 2 0 0 2 2 2 0 Sporulation protein YhaL Corona_nucleoca PF00937.13 AEO59922.1 - 3.7 6.4 11.4 6.7 5.5 7.9 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF566 PF04484.7 AEO59922.1 - 6.2 6.2 13.1 10 5.4 9.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) Period_C PF12114.3 AEO59922.1 - 6.3 6.3 12.2 12 5.4 8.5 1.4 1 0 0 1 1 1 0 Period protein 2/3C-terminal region PUF PF00806.14 AEO59923.1 - 2.6e-14 51.7 0.0 0.44 10.1 0.0 6.7 6 0 0 6 6 6 6 Pumilio-family RNA binding repeat Mucin PF01456.12 AEO59924.1 - 0.0031 17.3 31.7 0.012 15.3 9.7 2.9 3 0 0 3 3 3 2 Mucin-like glycoprotein PAT1 PF09770.4 AEO59924.1 - 2.4 6.2 13.9 3.4 5.7 9.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 XFP_N PF09364.5 AEO59925.1 - 3e-176 585.5 0.0 3.9e-176 585.2 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP PF03894.10 AEO59925.1 - 1.1e-81 272.7 0.0 2.4e-81 271.5 0.0 1.6 2 0 0 2 2 2 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.5 AEO59925.1 - 6e-79 264.1 0.0 8.7e-79 263.6 0.0 1.2 1 0 0 1 1 1 1 XFP C-terminal domain RasGAP PF00616.14 AEO59926.1 - 5.7e-53 179.5 0.3 2.2e-52 177.5 0.0 2.0 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 AEO59926.1 - 2.7e-29 101.6 5.4 2.7e-29 101.6 3.7 2.1 2 0 0 2 2 2 1 RasGAP C-terminus MeMO_Hyd_G PF02964.11 AEO59926.1 - 0.012 15.5 0.2 0.026 14.4 0.2 1.5 1 0 0 1 1 1 0 Methane monooxygenase, hydrolase gamma chain MFS_1 PF07690.11 AEO59927.1 - 4.4e-26 91.4 17.0 5.9e-26 91.0 11.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO59927.1 - 9.7e-08 31.0 8.9 1.4e-07 30.5 6.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter DUF4642 PF15484.1 AEO59927.1 - 0.051 13.5 0.3 0.077 12.9 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4642) DUF1228 PF06779.9 AEO59927.1 - 0.14 12.1 5.4 0.058 13.4 1.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1228) CDC45 PF02724.9 AEO59927.1 - 0.19 9.7 0.1 0.24 9.3 0.1 1.1 1 0 0 1 1 1 0 CDC45-like protein HUN PF08729.5 AEO59929.1 - 1e-13 50.8 1.3 2.2e-13 49.8 0.9 1.5 1 0 0 1 1 1 1 HPC2 and ubinuclein domain RPAP1_C PF08620.5 AEO59930.1 - 2e-30 104.4 0.0 3.6e-30 103.6 0.0 1.4 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 AEO59930.1 - 3.9e-18 64.7 1.6 6.6e-18 64.0 1.1 1.4 1 0 0 1 1 1 1 RPAP1-like, N-terminal ELYS PF13934.1 AEO59931.1 - 9.8e-61 205.3 0.0 1.2e-60 205.0 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly Linker_histone PF00538.14 AEO59933.1 - 8.3e-24 83.4 0.3 2.1e-23 82.2 0.2 1.7 1 0 0 1 1 1 1 linker histone H1 and H5 family CT47 PF15623.1 AEO59933.1 - 5.9 6.5 15.8 10 5.7 11.0 1.3 1 0 0 1 1 1 0 Cancer/testis gene family 47 Gti1_Pac2 PF09729.4 AEO59934.1 - 1.1e-46 158.7 0.3 2.3e-44 151.2 0.2 2.3 1 1 0 1 1 1 1 Gti1/Pac2 family tRNA-synt_2 PF00152.15 AEO59936.1 - 3.7e-67 226.4 0.0 4.9e-67 226.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 AEO59936.1 - 3.5e-07 29.9 0.0 6.1e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain FRG1 PF06229.7 AEO59936.1 - 0.057 12.8 0.0 0.19 11.1 0.0 1.7 1 1 1 2 2 2 0 FRG1-like family tRNA-synt_2d PF01409.15 AEO59936.1 - 0.062 12.4 0.0 7.7 5.6 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) DUF2263 PF10021.4 AEO59937.1 - 6.5e-11 42.4 0.0 1e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Sec23_trunk PF04811.10 AEO59938.1 - 2.9e-51 174.1 0.0 2.2e-50 171.3 0.0 2.4 2 1 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 AEO59938.1 - 1e-21 76.2 0.1 1.8e-21 75.5 0.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 AEO59938.1 - 1.2e-18 67.3 0.0 2.1e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 AEO59938.1 - 1.1e-17 63.2 4.2 2.2e-17 62.3 2.9 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 AEO59938.1 - 2.2e-05 24.0 0.0 5.4e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat CPSF100_C PF13299.1 AEO59939.1 - 8.1e-44 149.6 0.1 8.4e-43 146.3 0.0 2.6 2 1 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 AEO59939.1 - 7.8e-27 93.7 0.0 1.9e-26 92.4 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.7 AEO59939.1 - 2.5e-07 30.3 0.0 5.7e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B PF00753.22 AEO59939.1 - 0.036 13.7 0.4 0.24 11.0 0.3 2.2 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily BolA PF01722.13 AEO59940.1 - 5.3e-21 74.3 0.0 6.5e-21 74.0 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein NIF3 PF01784.13 AEO59941.1 - 1.2e-60 205.0 0.0 1.5e-60 204.7 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Vps51 PF08700.6 AEO59942.1 - 7.2e-24 83.4 0.0 2.2e-23 81.8 0.0 1.8 1 0 0 1 1 1 1 Vps51/Vps67 DUF2201_N PF13203.1 AEO59942.1 - 0.081 12.0 3.5 0.023 13.8 0.5 1.6 2 0 0 2 2 2 0 Putative metallopeptidase domain COG5 PF10392.4 AEO59942.1 - 0.31 11.0 1.6 0.33 10.9 0.0 1.8 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DUF605 PF04652.11 AEO59942.1 - 8.3 5.6 14.5 12 5.1 10.0 1.2 1 0 0 1 1 1 0 Vta1 like DUF1767 PF08585.7 AEO59943.1 - 1.8e-06 28.0 0.0 3.6e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) TPR_11 PF13414.1 AEO59944.1 - 1.8e-47 158.8 36.8 1.4e-08 34.2 0.0 12.3 10 2 3 13 13 13 11 TPR repeat TPR_16 PF13432.1 AEO59944.1 - 1e-41 140.7 44.4 6.9e-08 32.9 0.0 13.0 11 2 2 13 13 12 9 Tetratricopeptide repeat TPR_2 PF07719.12 AEO59944.1 - 4.1e-35 116.8 37.2 0.0009 18.9 0.0 15.5 14 0 0 14 14 14 9 Tetratricopeptide repeat TPR_19 PF14559.1 AEO59944.1 - 2.4e-33 114.2 22.6 5.1e-08 33.1 0.8 11.8 10 2 2 12 12 12 6 Tetratricopeptide repeat TPR_14 PF13428.1 AEO59944.1 - 4.8e-30 101.3 47.0 0.001 19.5 0.1 16.3 14 4 4 18 18 15 8 Tetratricopeptide repeat TPR_17 PF13431.1 AEO59944.1 - 3.5e-29 98.5 15.2 0.17 12.1 0.0 16.8 18 0 0 18 18 18 6 Tetratricopeptide repeat TPR_1 PF00515.23 AEO59944.1 - 8.2e-27 91.6 30.0 0.00013 21.3 0.0 14.8 14 0 0 14 14 14 6 Tetratricopeptide repeat TPR_12 PF13424.1 AEO59944.1 - 2.8e-20 72.0 50.0 6.9e-05 22.7 0.1 12.7 7 5 6 13 13 13 6 Tetratricopeptide repeat TPR_8 PF13181.1 AEO59944.1 - 1.8e-19 67.9 21.6 0.023 14.4 0.0 13.1 12 2 2 14 14 14 5 Tetratricopeptide repeat TPR_6 PF13174.1 AEO59944.1 - 6e-13 48.3 23.5 0.65 10.5 0.0 13.5 14 0 0 14 14 13 3 Tetratricopeptide repeat TPR_7 PF13176.1 AEO59944.1 - 1.1e-12 46.7 28.7 0.021 14.6 0.0 13.7 14 2 1 15 15 14 3 Tetratricopeptide repeat TPR_9 PF13371.1 AEO59944.1 - 2.2e-05 24.2 16.0 0.011 15.5 0.0 8.5 9 1 1 10 10 9 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 AEO59944.1 - 3.6e-05 23.5 1.0 2.8 7.8 0.1 5.1 4 1 0 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.1 AEO59944.1 - 4.6e-05 23.4 15.4 8.1 6.6 0.0 7.3 6 1 0 6 6 5 1 Tetratricopeptide repeat Coatomer_WDAD PF04053.9 AEO59944.1 - 0.017 13.9 0.0 0.035 12.8 0.0 1.4 1 0 0 1 1 1 0 Coatomer WD associated region ChAPs PF09295.5 AEO59944.1 - 0.033 12.9 1.9 40 2.8 0.1 4.7 5 0 0 5 5 5 0 ChAPs (Chs5p-Arf1p-binding proteins) PPTA PF01239.17 AEO59944.1 - 0.08 12.3 0.0 3.3 7.2 0.0 3.1 3 0 0 3 3 3 0 Protein prenyltransferase alpha subunit repeat Apc5 PF12862.2 AEO59944.1 - 0.53 10.1 11.3 1.5 8.6 0.2 5.5 6 0 0 6 6 5 0 Anaphase-promoting complex subunit 5 Nrap PF03813.9 AEO59945.1 - 0 1122.8 0.0 0 1122.6 0.0 1.0 1 0 0 1 1 1 1 Nrap protein ASF1_hist_chap PF04729.8 AEO59946.1 - 8.5e-69 230.0 0.0 1.1e-68 229.7 0.0 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone Suf PF05843.9 AEO59947.1 - 4.9e-87 292.2 5.8 1.2e-85 287.6 0.0 3.5 4 1 0 4 4 4 2 Suppressor of forked protein (Suf) Sigma70_ner PF04546.8 AEO59947.1 - 0.021 14.4 4.3 0.041 13.4 3.0 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Piwi PF02171.12 AEO59949.1 - 4.3e-78 262.3 0.4 5.6e-78 261.9 0.3 1.1 1 0 0 1 1 1 1 Piwi domain Lgl_C PF08596.5 AEO59950.1 - 9.4e-119 396.3 0.0 3.8e-118 394.3 0.0 1.9 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 AEO59950.1 - 3.4e-05 23.5 4.8 0.082 12.8 0.1 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat PQQ_2 PF13360.1 AEO59950.1 - 4.9e-05 22.9 0.3 0.024 14.0 0.1 2.5 1 1 0 2 2 2 2 PQQ-like domain Nucleoporin_N PF08801.6 AEO59950.1 - 0.036 12.8 0.0 2.8 6.5 0.0 2.3 2 0 0 2 2 2 0 Nup133 N terminal like Apc4_WD40 PF12894.2 AEO59950.1 - 0.16 11.5 0.0 24 4.5 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Glyco_hydro_3 PF00933.16 AEO59951.1 - 1.3e-09 37.4 0.1 7.1e-09 35.0 0.0 1.8 1 1 1 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain DUF2102 PF09875.4 AEO59951.1 - 0.15 11.6 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2102) Glyco_hydro_3 PF00933.16 AEO59952.1 - 1.8e-06 27.1 0.0 1.4e-05 24.2 0.0 1.9 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain MFS_1 PF07690.11 AEO59953.1 - 2.8e-39 134.8 37.2 4e-39 134.3 25.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_61 PF03443.9 AEO59955.1 - 1.9e-63 214.2 0.0 2.3e-63 213.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Clp1 PF06807.9 AEO59956.1 - 5.8e-07 29.4 0.0 0.00097 18.9 0.0 2.4 3 0 0 3 3 3 2 Pre-mRNA cleavage complex II protein Clp1 Ribosomal_60s PF00428.14 AEO59956.1 - 5.1e-05 23.6 9.5 0.0054 17.0 1.2 2.5 2 0 0 2 2 2 2 60s Acidic ribosomal protein PBP1_TM PF14812.1 AEO59956.1 - 0.00013 22.1 0.5 0.00031 21.0 0.4 1.5 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal MobB PF03205.9 AEO59956.1 - 0.013 15.1 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 AEO59956.1 - 0.029 15.1 0.1 0.081 13.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 AEO59956.1 - 0.089 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Myc_N PF01056.13 AEO59956.1 - 2.7 7.0 6.0 2 7.5 0.3 2.2 2 0 0 2 2 2 0 Myc amino-terminal region Nucleoplasmin PF03066.10 AEO59956.1 - 3.5 7.1 8.2 0.071 12.6 0.7 1.7 2 0 0 2 2 2 0 Nucleoplasmin RNA_polI_A34 PF08208.6 AEO59957.1 - 1.7e-22 80.1 20.2 1.7e-22 80.1 14.0 6.7 2 2 3 5 5 5 1 DNA-directed RNA polymerase I subunit RPA34.5 PAP2 PF01569.16 AEO59958.1 - 5.3e-13 48.7 4.2 5.3e-13 48.7 2.9 2.1 1 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 AEO59958.1 - 2.8e-07 30.2 6.1 7.5e-07 28.8 4.2 1.7 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.1 AEO59958.1 - 1.7 8.9 5.8 1.8 8.9 0.8 2.5 2 0 0 2 2 2 0 PAP2 superfamily C-terminal Pkinase PF00069.20 AEO59959.1 - 3.8e-69 232.7 0.0 5.1e-69 232.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO59959.1 - 3.3e-29 101.7 0.0 4.4e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO59959.1 - 4.2e-06 25.9 0.0 6.9e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AEO59959.1 - 0.00022 21.0 0.1 0.00038 20.2 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 AEO59959.1 - 0.00023 20.3 0.0 0.0004 19.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 AEO59959.1 - 0.019 14.3 0.0 0.041 13.2 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Ebola_NP PF05505.7 AEO59959.1 - 1.7 6.5 5.7 2.7 5.9 4.0 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein GNAT_acetyltr_2 PF13718.1 AEO59960.1 - 1.2e-81 272.7 0.0 1.9e-81 272.0 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 AEO59960.1 - 5.3e-65 218.3 0.0 1.5e-64 216.8 0.0 1.8 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 AEO59960.1 - 2.8e-40 135.8 0.0 6.9e-40 134.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 AEO59960.1 - 4.1e-35 119.9 0.5 1.2e-34 118.3 0.3 1.9 1 0 0 1 1 1 1 Possible tRNA binding domain AAA_22 PF13401.1 AEO59960.1 - 0.0029 17.7 0.1 0.29 11.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain Acetyltransf_7 PF13508.1 AEO59960.1 - 0.016 15.3 0.0 0.049 13.8 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RF-1 PF00472.15 AEO59961.1 - 2.4e-14 53.1 0.5 3.4e-14 52.5 0.3 1.3 1 0 0 1 1 1 1 RF-1 domain RRM_1 PF00076.17 AEO59962.1 - 1e-06 28.2 0.0 2.1e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO59962.1 - 0.00038 20.3 0.0 0.00072 19.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO59962.1 - 0.0021 17.8 0.0 0.0035 17.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_S10 PF00450.17 AEO59963.1 - 1.5e-75 254.9 0.0 2.8e-75 254.0 0.0 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase LETM1 PF07766.8 AEO59964.1 - 1.6e-07 30.6 0.0 3.1e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 LETM1-like protein Mucin PF01456.12 AEO59964.1 - 2.8 7.7 22.4 5.5 6.7 15.5 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Mannosyl_trans3 PF11051.3 AEO59965.1 - 7e-65 219.0 0.0 2.2e-64 217.4 0.0 1.8 1 1 0 1 1 1 1 Mannosyltransferase putative Zip PF02535.17 AEO59965.1 - 0.033 13.2 5.4 0.024 13.6 0.7 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter CDC27 PF09507.5 AEO59965.1 - 0.053 12.7 5.3 0.097 11.8 3.7 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 FLO_LFY PF01698.11 AEO59965.1 - 0.41 9.4 10.1 1.2 7.9 4.0 2.1 2 0 0 2 2 2 0 Floricaula / Leafy protein DUF3245 PF11595.3 AEO59965.1 - 1.6 8.9 9.4 0.33 11.2 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) FAM176 PF14851.1 AEO59965.1 - 7 6.3 7.3 23 4.6 0.2 2.3 2 0 0 2 2 2 0 FAM176 family Pyr_redox_3 PF13738.1 AEO59966.1 - 2.8e-18 66.7 0.1 2.5e-17 63.5 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 AEO59966.1 - 9.8e-10 37.2 0.0 8e-09 34.2 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 AEO59966.1 - 8.6e-09 35.5 0.0 1.1e-08 35.1 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 AEO59966.1 - 8e-08 31.5 0.0 4.2e-07 29.2 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 AEO59966.1 - 5.3e-05 23.1 0.3 0.00024 21.0 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Ribonuc_L-PSP PF01042.16 AEO59967.1 - 7.2e-41 138.7 0.0 8.1e-41 138.5 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP NAD_binding_6 PF08030.7 AEO59968.1 - 2.2e-17 63.3 0.0 3.5e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 AEO59968.1 - 2.1e-07 30.7 0.0 2.9e-06 27.1 0.0 2.5 2 2 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.14 AEO59968.1 - 2.8e-07 30.6 8.9 5.2e-07 29.7 6.1 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 AEO59968.1 - 1.3e-06 28.9 0.0 0.0073 16.8 0.0 2.4 1 1 1 2 2 2 2 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 AEO59968.1 - 0.013 15.5 0.0 0.41 10.8 0.0 2.9 3 1 0 3 3 3 0 Oxidoreductase FAD-binding domain VanZ PF04892.7 AEO59969.1 - 1.5e-14 54.0 2.9 2.1e-14 53.5 2.0 1.2 1 0 0 1 1 1 1 VanZ like family RseC_MucC PF04246.7 AEO59969.1 - 0.15 11.6 0.5 7 6.2 0.0 2.3 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Bromodomain PF00439.20 AEO59970.1 - 3.2e-19 68.6 0.2 7.4e-19 67.4 0.1 1.6 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.8 AEO59970.1 - 1.7e-10 40.4 0.0 8.2e-10 38.2 0.0 2.2 1 1 0 1 1 1 1 Bromodomain associated SHMT PF00464.14 AEO59971.1 - 3.6e-208 690.7 0.0 4.5e-208 690.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 AEO59971.1 - 0.00097 18.3 0.0 0.0019 17.4 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 AEO59971.1 - 0.0013 17.5 0.1 0.0024 16.7 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V PAT1 PF09770.4 AEO59972.1 - 0.69 8.0 40.0 1.3 7.1 27.7 1.5 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF155 PF02582.9 AEO59973.1 - 4.5e-44 150.4 0.0 1.2e-43 149.0 0.0 1.7 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 Cupin_3 PF05899.7 AEO59973.1 - 0.12 11.7 0.5 0.47 9.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF861) RINT1_TIP1 PF04437.8 AEO59974.1 - 2.2e-68 231.0 0.0 3.6e-68 230.3 0.0 1.3 1 0 0 1 1 1 1 RINT-1 / TIP-1 family ADIP PF11559.3 AEO59974.1 - 0.0089 15.9 2.0 0.0089 15.9 1.4 2.0 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding DUF4164 PF13747.1 AEO59974.1 - 0.013 15.6 4.9 0.05 13.7 2.1 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF4164) NifQ PF04891.7 AEO59974.1 - 0.047 13.8 1.4 0.18 11.9 1.0 2.0 1 0 0 1 1 1 0 NifQ Myosin_tail_1 PF01576.14 AEO59974.1 - 0.07 10.8 6.0 0.015 13.0 1.4 1.7 2 0 0 2 2 2 0 Myosin tail Mito_carr PF00153.22 AEO59975.1 - 6.5e-62 205.2 1.8 1.4e-21 76.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Sec34 PF04136.10 AEO59976.1 - 4.4e-21 75.2 0.0 2.7e-16 59.6 0.0 2.3 2 0 0 2 2 2 2 Sec34-like family RCC1 PF00415.13 AEO59977.1 - 1.1e-29 102.3 5.7 2.5e-05 24.3 0.8 7.1 6 1 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 AEO59977.1 - 2e-15 55.9 16.4 1.2e-09 37.4 0.0 7.1 6 1 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat Y_phosphatase PF00102.22 AEO59978.1 - 6.2e-46 156.6 0.0 9.2e-37 126.6 0.0 3.0 2 1 0 2 2 2 2 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 AEO59978.1 - 0.00019 21.4 0.0 0.00055 20.0 0.0 1.9 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.15 AEO59978.1 - 0.00022 20.8 0.0 0.00044 19.8 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Ribosomal_60s PF00428.14 AEO59978.1 - 0.0025 18.1 3.8 0.0077 16.6 2.6 1.8 1 0 0 1 1 1 1 60s Acidic ribosomal protein Y_phosphatase3 PF13350.1 AEO59978.1 - 0.026 14.7 0.0 0.062 13.5 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF3590 PF12148.3 AEO59978.1 - 0.064 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3590) FAM176 PF14851.1 AEO59978.1 - 4.6 6.9 6.1 5.5 6.6 0.2 2.2 2 0 0 2 2 2 0 FAM176 family Folliculin PF11704.3 AEO59979.1 - 1.9e-26 92.6 0.0 6.9e-26 90.8 0.0 1.9 2 1 0 2 2 2 1 Vesicle coat protein involved in Golgi to plasma membrane transport AAA PF00004.24 AEO59980.1 - 2.6e-45 153.8 0.5 6.1e-45 152.6 0.0 1.9 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 AEO59980.1 - 7e-09 35.5 0.4 2.9e-08 33.5 0.1 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 AEO59980.1 - 4.6e-08 33.1 0.0 1e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 AEO59980.1 - 3.5e-07 30.3 0.0 1.5e-06 28.3 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 AEO59980.1 - 1.5e-06 28.3 1.5 0.001 19.1 0.0 2.8 2 1 1 3 3 2 2 AAA domain DUF815 PF05673.8 AEO59980.1 - 3.4e-06 26.1 0.0 7.3e-06 25.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 AEO59980.1 - 0.00019 21.3 0.0 0.00083 19.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 AEO59980.1 - 0.00036 19.6 0.0 0.00084 18.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 AEO59980.1 - 0.00038 20.4 0.0 0.00081 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AEO59980.1 - 0.00057 20.6 0.0 0.0023 18.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain NACHT PF05729.7 AEO59980.1 - 0.00093 18.8 0.5 0.057 13.0 0.0 2.8 2 1 0 3 3 2 1 NACHT domain Zeta_toxin PF06414.7 AEO59980.1 - 0.0012 17.9 0.1 0.0038 16.3 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_19 PF13245.1 AEO59980.1 - 0.0013 18.4 0.2 0.0035 17.0 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain NTPase_1 PF03266.10 AEO59980.1 - 0.0014 18.3 0.0 0.0089 15.7 0.0 2.2 2 0 0 2 2 2 1 NTPase RNA_helicase PF00910.17 AEO59980.1 - 0.0017 18.4 0.0 0.0038 17.3 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_11 PF13086.1 AEO59980.1 - 0.0033 17.0 0.1 0.016 14.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 AEO59980.1 - 0.0035 16.9 0.0 0.011 15.2 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 AEO59980.1 - 0.0041 17.4 1.0 0.85 9.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 AEO59980.1 - 0.0048 16.7 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 AEO59980.1 - 0.0053 16.3 0.0 0.041 13.5 0.0 2.1 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Mg_chelatase PF01078.16 AEO59980.1 - 0.0064 15.6 0.2 0.013 14.6 0.1 1.6 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 AEO59980.1 - 0.0072 16.0 0.5 0.058 13.0 0.0 2.5 2 1 0 2 2 2 1 Archaeal ATPase TIP49 PF06068.8 AEO59980.1 - 0.0072 15.0 0.0 0.012 14.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_30 PF13604.1 AEO59980.1 - 0.0079 15.7 0.0 0.021 14.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AEO59980.1 - 0.0088 16.3 0.0 0.025 14.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 AEO59980.1 - 0.009 15.4 0.7 0.024 14.0 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_24 PF13479.1 AEO59980.1 - 0.011 15.3 0.4 0.03 13.9 0.1 1.8 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.1 AEO59980.1 - 0.014 14.7 2.9 0.07 12.5 0.1 2.7 2 1 1 3 3 3 0 AAA domain Bac_DnaA PF00308.13 AEO59980.1 - 0.015 14.9 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein Cast PF10174.4 AEO59980.1 - 0.018 13.0 2.3 0.032 12.2 0.9 1.7 2 0 0 2 2 2 0 RIM-binding protein of the cytomatrix active zone KaiC PF06745.8 AEO59980.1 - 0.024 13.7 0.9 0.45 9.5 0.0 2.6 3 0 0 3 3 3 0 KaiC Viral_Hsp90 PF03225.9 AEO59980.1 - 0.037 12.3 0.0 0.055 11.7 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue Sigma54_activat PF00158.21 AEO59980.1 - 0.041 13.3 0.1 1.3 8.4 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AFG1_ATPase PF03969.11 AEO59980.1 - 0.047 12.4 0.0 0.085 11.6 0.0 1.4 1 0 0 1 1 1 0 AFG1-like ATPase Sigma54_activ_2 PF14532.1 AEO59980.1 - 0.059 13.4 0.1 0.37 10.8 0.0 2.4 2 1 0 2 2 2 0 Sigma-54 interaction domain NB-ARC PF00931.17 AEO59980.1 - 0.11 11.3 0.0 0.2 10.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Parvo_NS1 PF01057.12 AEO59980.1 - 0.16 10.8 0.0 0.31 9.8 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 SR-25 PF10500.4 AEO59981.1 - 0.19 11.1 6.1 0.25 10.7 4.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CRAL_TRIO PF00650.15 AEO59982.1 - 7e-37 126.3 0.0 1e-36 125.8 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 AEO59982.1 - 4.1e-11 42.8 1.3 1.9e-10 40.6 0.1 2.6 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 AEO59982.1 - 0.00013 21.8 0.0 0.001 18.9 0.0 2.1 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain Prefoldin PF02996.12 AEO59983.1 - 3.9e-36 123.3 0.0 5.8e-36 122.7 0.0 1.3 1 0 0 1 1 1 1 Prefoldin subunit HR1 PF02185.11 AEO59983.1 - 0.0032 17.1 0.7 0.027 14.1 0.1 2.3 2 0 0 2 2 2 1 Hr1 repeat Filament PF00038.16 AEO59983.1 - 0.0044 16.5 0.8 1 8.7 0.0 2.1 2 0 0 2 2 2 2 Intermediate filament protein Prefoldin_2 PF01920.15 AEO59983.1 - 0.0047 16.6 3.7 0.019 14.7 0.0 2.6 3 0 0 3 3 3 1 Prefoldin subunit DUF2353 PF09789.4 AEO59983.1 - 0.054 12.7 2.0 0.089 12.0 1.4 1.3 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) KLRAQ PF10205.4 AEO59983.1 - 0.2 11.7 4.3 1.8 8.6 0.1 2.2 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein SlyX PF04102.7 AEO59983.1 - 0.81 10.1 3.0 4.4 7.7 0.1 2.8 3 1 0 3 3 3 0 SlyX Asp PF00026.18 AEO59984.1 - 1.6e-111 372.6 0.6 1.8e-111 372.3 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 AEO59984.1 - 2.1e-13 50.5 0.0 2.2e-12 47.2 0.0 2.2 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 AEO59984.1 - 6.7e-07 29.7 0.2 0.089 13.3 0.0 3.0 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 AEO59984.1 - 0.0024 17.4 0.0 0.021 14.3 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Alpha-amylase_C PF02806.13 AEO59984.1 - 0.12 12.5 0.0 0.92 9.6 0.0 2.2 2 0 0 2 2 2 0 Alpha amylase, C-terminal all-beta domain DNA_pol_A_exo1 PF01612.15 AEO59985.1 - 2.3e-39 134.6 0.3 4.1e-39 133.8 0.2 1.4 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 AEO59985.1 - 1.6e-26 92.3 0.1 1.6e-26 92.3 0.1 2.1 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.18 AEO59985.1 - 3.3e-13 49.1 0.0 9.1e-13 47.7 0.0 1.9 1 0 0 1 1 1 1 HRDC domain Gpi1 PF05024.10 AEO59986.1 - 2.8e-67 226.0 7.0 5.7e-67 225.0 4.9 1.5 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) 7tm_1 PF00001.16 AEO59986.1 - 0.0005 19.3 1.2 0.00098 18.3 0.9 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF3333 PF11812.3 AEO59986.1 - 0.11 12.4 0.8 0.22 11.5 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3333) Tom37_C PF11801.3 AEO59986.1 - 0.14 11.9 2.0 9.5 6.0 0.8 2.8 3 0 0 3 3 3 0 Tom37 C-terminal domain TBCC PF07986.7 AEO59987.1 - 1.4e-30 105.1 0.1 3.1e-30 104.0 0.1 1.6 1 0 0 1 1 1 1 Tubulin binding cofactor C Med9 PF07544.8 AEO59988.1 - 8.3e-15 54.2 0.1 5.8e-14 51.5 0.1 2.1 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 TFIIA PF03153.8 AEO59988.1 - 0.073 12.9 4.2 0.088 12.6 2.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3640 PF12342.3 AEO59988.1 - 3.1 7.3 5.2 2.4 7.7 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3640) iPGM_N PF06415.8 AEO59989.1 - 1.8e-74 249.8 0.0 2.4e-74 249.4 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.13 AEO59989.1 - 2e-69 233.7 0.0 2.3e-69 233.5 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.17 AEO59989.1 - 5.4e-06 25.9 0.0 8.2e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 AEO59989.1 - 6.3e-05 22.3 0.0 0.0012 18.0 0.0 2.2 1 1 0 1 1 1 1 Sulfatase ATP-synt_C PF00137.16 AEO59990.1 - 2.7e-16 59.2 11.0 5.2e-16 58.3 7.6 1.5 1 0 0 1 1 1 1 ATP synthase subunit C Inhibitor_I36 PF03995.8 AEO59990.1 - 0.072 13.4 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase inhibitor family I36 2Fe-2S_Ferredox PF11591.3 AEO59990.1 - 5.2 6.7 9.5 1.4 8.6 3.5 2.3 2 0 0 2 2 2 0 Ferredoxin chloroplastic transit peptide MOZ_SAS PF01853.13 AEO59991.1 - 6.7e-49 165.6 0.0 3.6e-48 163.2 0.0 1.9 1 1 0 1 1 1 1 MOZ/SAS family DNA_methylase PF00145.12 AEO59992.1 - 6.7e-31 107.6 0.0 3.4e-24 85.5 0.0 2.2 2 0 0 2 2 2 2 C-5 cytosine-specific DNA methylase BAH PF01426.13 AEO59992.1 - 9.4e-07 28.6 0.0 0.01 15.6 0.0 2.5 2 0 0 2 2 2 2 BAH domain Drc1-Sld2 PF11719.3 AEO59994.1 - 1.4e-39 136.4 15.8 1.8e-39 136.0 10.9 1.2 1 0 0 1 1 1 1 DNA replication and checkpoint protein zf-RING_2 PF13639.1 AEO59995.1 - 3.5e-08 33.1 12.7 5.3e-08 32.5 8.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 AEO59995.1 - 5.5e-07 29.5 8.8 8.2e-07 28.9 6.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AEO59995.1 - 1.2e-06 28.0 7.4 1.8e-06 27.4 5.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AEO59995.1 - 1.6e-05 24.4 7.8 2.3e-05 23.9 5.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 AEO59995.1 - 0.0022 18.0 10.4 0.0061 16.6 7.2 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger DUF1152 PF06626.7 AEO59995.1 - 0.084 11.9 0.2 0.14 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1152) Rpn3_C PF08375.6 AEO59996.1 - 1.3e-24 86.4 1.4 2.9e-24 85.2 1.0 1.7 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 AEO59996.1 - 1.1e-19 70.6 0.5 4.4e-19 68.7 0.0 2.3 3 0 0 3 3 3 1 PCI domain TPR_2 PF07719.12 AEO59996.1 - 0.014 15.2 0.1 0.048 13.5 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TFIID_20kDa PF03847.8 AEO59997.1 - 1.1e-17 64.1 0.0 1.7e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Pollen_allerg_2 PF01620.11 AEO59997.1 - 0.028 14.7 1.5 0.028 14.7 1.0 3.6 2 1 1 4 4 4 0 Ribonuclease (pollen allergen) DASH_Spc34 PF08657.5 AEO60000.1 - 1.2e-46 159.5 0.0 1.6e-46 159.0 0.0 1.2 1 0 0 1 1 1 1 DASH complex subunit Spc34 Dmrt1 PF12374.3 AEO60000.1 - 1.3 9.3 5.4 0.59 10.5 2.0 1.7 1 1 1 2 2 2 0 Double-sex mab3 related transcription factor 1 DSBA PF01323.15 AEO60001.1 - 1.8e-41 141.8 0.0 2.1e-41 141.6 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 AEO60001.1 - 1.5e-05 25.0 0.0 4.2e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.1 AEO60001.1 - 0.02 14.6 0.0 1.9 8.3 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin domain Fig1 PF12351.3 AEO60002.1 - 4.7e-56 189.5 3.2 4.7e-56 189.5 2.2 2.0 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 AEO60002.1 - 5.8e-10 39.1 7.9 7.5e-10 38.7 5.5 1.2 1 0 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.8 AEO60002.1 - 0.00015 20.7 5.7 0.00015 20.7 4.0 1.8 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF898) MLTD_N PF06474.7 AEO60002.1 - 1 9.5 4.8 1.5 9.0 1.9 2.3 2 0 0 2 2 2 0 MltD lipid attachment motif ODV-E18 PF10717.4 AEO60002.1 - 2.3 7.7 10.3 1.3 8.5 1.1 3.2 3 0 0 3 3 3 0 Occlusion-derived virus envelope protein ODV-E18 DUF2976 PF11190.3 AEO60002.1 - 5.1 6.6 0.0 5.1 6.6 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2976) DUF4131 PF13567.1 AEO60002.1 - 6.5 6.1 13.3 0.24 10.8 0.2 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) DUF202 PF02656.10 AEO60002.1 - 8.9 6.6 14.4 22 5.3 4.1 3.5 1 1 1 2 2 2 0 Domain of unknown function (DUF202) Glyco_hydro_47 PF01532.15 AEO60003.1 - 1.9e-173 577.3 0.0 2.3e-173 577.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 OapA_N PF08525.6 AEO60003.1 - 0.28 10.9 2.2 0.58 10.0 1.5 1.5 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif SseC PF04888.7 AEO60003.1 - 0.68 9.2 2.6 1.1 8.5 1.8 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Pkinase PF00069.20 AEO60004.1 - 3e-65 219.9 0.0 4.6e-65 219.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO60004.1 - 2.1e-48 164.6 0.0 3.4e-48 163.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO60004.1 - 1.8e-08 33.7 0.0 3.6e-06 26.1 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 AEO60004.1 - 0.0077 15.3 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Cellulase PF00150.13 AEO60005.1 - 2e-14 53.4 0.9 9e-09 34.9 0.2 2.5 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.10 AEO60005.1 - 0.0022 17.1 0.2 0.23 10.5 0.0 2.2 2 0 0 2 2 2 2 Beta-galactosidase Glyco_hydro_35 PF01301.14 AEO60005.1 - 0.053 12.8 0.1 0.095 12.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 DNA_primase_S PF01896.14 AEO60006.1 - 1.1e-54 184.2 0.1 1.9e-54 183.4 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit MutS_V PF00488.16 AEO60007.1 - 1e-97 326.1 0.0 1.6e-97 325.5 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 AEO60007.1 - 3.2e-40 138.1 0.9 3.2e-40 138.1 0.6 1.8 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.12 AEO60007.1 - 2e-21 76.4 1.4 4.3e-21 75.4 0.0 2.3 3 0 0 3 3 3 1 MutS domain II MutS_IV PF05190.13 AEO60007.1 - 5e-18 65.0 2.7 8.8e-18 64.2 0.3 2.7 3 0 0 3 3 3 1 MutS family domain IV Peptidase_M16 PF00675.15 AEO60007.1 - 0.013 15.2 0.1 0.045 13.5 0.0 1.9 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) MutS_I PF01624.15 AEO60007.1 - 0.018 15.0 0.0 0.12 12.3 0.0 2.3 2 0 0 2 2 2 0 MutS domain I AAA_22 PF13401.1 AEO60007.1 - 0.049 13.7 0.1 0.42 10.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain UCH PF00443.24 AEO60008.1 - 1.6e-28 99.5 0.0 8.6e-28 97.1 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 AEO60008.1 - 1.9e-15 56.0 0.0 0.00018 20.8 0.0 3.7 3 0 0 3 3 3 3 A repeated domain in UCH-protein UCH_1 PF13423.1 AEO60008.1 - 7.5e-11 42.0 2.5 0.00029 20.3 0.4 2.7 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase PUB PF09409.5 AEO60008.1 - 3.6e-06 26.6 0.0 7.1e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 PUB domain RasGAP_C PF03836.10 AEO60008.1 - 0.15 11.7 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 RasGAP C-terminus Tim17 PF02466.14 AEO60009.1 - 9.3e-13 48.3 8.8 1.8e-12 47.4 6.1 1.4 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Acyl-CoA_dh_1 PF00441.19 AEO60010.1 - 1.1e-41 142.4 0.1 1.6e-41 141.9 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 AEO60010.1 - 3e-21 74.6 0.2 6e-21 73.7 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 AEO60010.1 - 5.7e-21 74.1 0.3 1.1e-20 73.2 0.2 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 AEO60010.1 - 1.8e-16 60.6 0.0 5.2e-16 59.2 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 AEO60010.1 - 3.3e-08 33.8 0.0 7e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain XPG_I PF00867.13 AEO60011.1 - 8.4e-31 105.8 1.1 1e-30 105.6 0.0 1.7 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.12 AEO60011.1 - 8.8e-31 106.1 0.0 8.8e-31 106.1 0.0 2.1 2 0 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.15 AEO60011.1 - 1e-05 25.6 0.9 7.7e-05 22.8 0.0 2.6 3 0 0 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold TniB PF05621.6 AEO60011.1 - 0.018 13.7 0.0 0.027 13.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein XPG_I_2 PF12813.2 AEO60011.1 - 0.042 13.3 0.7 0.07 12.6 0.0 1.8 2 0 0 2 2 2 0 XPG domain containing NAD_binding_6 PF08030.7 AEO60012.1 - 3.2e-31 108.3 0.0 5.8e-31 107.5 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 AEO60012.1 - 5.9e-21 74.3 0.0 1.8e-20 72.7 0.0 1.9 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 AEO60012.1 - 1.1e-16 61.0 18.2 1.3e-16 60.7 6.8 2.3 1 1 1 2 2 2 2 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 AEO60012.1 - 0.003 17.6 0.0 0.0075 16.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain UQ_con PF00179.21 AEO60013.1 - 1.8e-52 176.5 0.0 2e-52 176.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AEO60013.1 - 0.00022 20.9 0.0 0.00026 20.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 AEO60013.1 - 0.00069 19.4 0.0 0.00078 19.3 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 AEO60013.1 - 0.011 15.3 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 UEV domain Acyl-CoA_dh_N PF02771.11 AEO60014.1 - 1.1e-24 87.1 0.1 2.4e-24 86.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 AEO60014.1 - 6.3e-24 84.7 0.4 1.1e-23 84.0 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 AEO60014.1 - 2.7e-14 52.3 0.0 6.4e-14 51.2 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 AEO60014.1 - 1.4e-08 35.0 0.2 2.4e-08 34.3 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain SYS1 PF09801.4 AEO60015.1 - 1.9e-48 164.1 3.2 2.1e-48 163.9 2.2 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network CHD5 PF04420.9 AEO60015.1 - 0.22 11.1 2.0 0.2 11.2 0.7 1.4 1 1 0 1 1 1 0 CHD5-like protein TrbE PF11100.3 AEO60015.1 - 0.25 11.2 4.7 0.41 10.5 2.4 1.9 1 1 1 2 2 2 0 Conjugal transfer protein TrbE DUF2306 PF10067.4 AEO60015.1 - 9.4 6.4 10.9 0.73 9.9 3.6 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2306) COX6B PF02297.12 AEO60016.1 - 1.1e-23 82.9 3.0 1.5e-23 82.6 2.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.4 AEO60016.1 - 0.0066 16.4 0.2 0.012 15.6 0.1 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 PIP5K PF01504.13 AEO60017.1 - 1.1e-86 290.0 0.1 1.5e-86 289.6 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Amidohydro_1 PF01979.15 AEO60018.1 - 4.5e-19 69.2 1.1 2e-10 40.8 0.0 3.1 3 0 0 3 3 3 3 Amidohydrolase family Amidohydro_4 PF13147.1 AEO60018.1 - 1.8e-14 54.4 13.6 2.3e-11 44.2 2.0 2.8 1 1 1 3 3 3 2 Amidohydrolase Amidohydro_5 PF13594.1 AEO60018.1 - 3e-09 36.5 0.0 9.3e-09 34.9 0.0 1.9 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 AEO60018.1 - 4.5e-06 26.1 9.4 5.1e-05 22.6 0.2 3.2 2 2 2 4 4 4 2 Amidohydrolase family ADH_zinc_N PF00107.21 AEO60019.1 - 7.8e-23 80.4 0.0 1.4e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 AEO60019.1 - 9.4e-07 29.7 0.0 3.4e-06 27.9 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF2993 PF11209.3 AEO60019.1 - 0.0072 16.2 0.2 0.01 15.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2993) AlaDh_PNT_C PF01262.16 AEO60019.1 - 0.038 13.5 0.1 0.067 12.7 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PhoH PF02562.11 AEO60019.1 - 0.11 11.7 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Aldo_ket_red PF00248.16 AEO60019.1 - 0.14 10.9 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Aldo/keto reductase family polyprenyl_synt PF00348.12 AEO60020.1 - 5.8e-56 189.2 0.2 1.6e-51 174.6 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase HEPPP_synt_1 PF07307.6 AEO60020.1 - 0.0086 15.5 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 DUF4406 PF14359.1 AEO60020.1 - 0.14 12.2 0.0 0.55 10.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4406) Vma12 PF11712.3 AEO60021.1 - 9e-37 125.9 0.0 1.3e-36 125.4 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF1358 PF07096.6 AEO60021.1 - 0.052 13.2 0.0 0.09 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1358) zf-C2H2_3 PF13878.1 AEO60022.1 - 8e-05 22.1 0.0 0.00015 21.2 0.0 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO PSDC PF12588.3 AEO60023.1 - 7.6e-47 158.4 0.0 1.1e-46 157.9 0.0 1.2 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.10 AEO60023.1 - 5.3e-38 130.3 0.0 7.7e-38 129.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Biotin_lipoyl_2 PF13533.1 AEO60023.1 - 0.0011 18.5 0.7 0.32 10.6 0.1 2.7 3 0 0 3 3 3 2 Biotin-lipoyl like Fungal_trans_2 PF11951.3 AEO60025.1 - 2e-26 92.4 3.7 1.9e-15 56.3 0.6 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO60025.1 - 1.5e-08 34.4 11.5 3.2e-08 33.3 8.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.14 AEO60025.1 - 0.15 11.8 6.4 0.38 10.5 3.8 2.3 2 0 0 2 2 2 0 AT hook motif AAA_16 PF13191.1 AEO60026.1 - 8.4e-06 25.8 2.4 0.0002 21.4 1.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 AEO60026.1 - 2.7e-05 24.0 0.0 4.4e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_25 PF13481.1 AEO60026.1 - 0.0018 17.6 0.4 0.016 14.6 0.2 2.5 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.1 AEO60026.1 - 0.043 13.9 0.1 0.11 12.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain Miro PF08477.8 AEO60026.1 - 0.05 14.0 0.0 2 8.9 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein DUF815 PF05673.8 AEO60026.1 - 0.078 11.8 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Apt1 PF10351.4 AEO60027.1 - 0.17 10.7 1.5 0.23 10.2 1.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4611 PF15387.1 AEO60027.1 - 0.23 11.6 8.9 6.1 7.0 3.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Nucleoplasmin PF03066.10 AEO60027.1 - 5.8 6.4 7.6 1.3 8.4 1.8 2.3 3 0 0 3 3 3 0 Nucleoplasmin Myb_DNA-binding PF00249.26 AEO60028.1 - 2.5e-19 69.0 11.3 2.8e-12 46.4 0.1 5.0 5 0 0 5 5 5 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 AEO60028.1 - 1.7e-15 56.8 11.8 3.5e-12 46.2 0.7 3.8 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 AEO60028.1 - 0.012 15.7 1.1 0.012 15.7 0.7 3.3 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain CDV3 PF15359.1 AEO60029.1 - 0.0071 16.4 3.4 0.0071 16.4 2.4 2.5 2 0 0 2 2 2 1 Carnitine deficiency-associated protein 3 DegT_DnrJ_EryC1 PF01041.12 AEO60029.1 - 0.0077 15.3 1.0 0.013 14.5 0.7 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Zip PF02535.17 AEO60029.1 - 2.3 7.1 13.8 1.8 7.5 2.5 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter Cu_amine_oxid PF01179.15 AEO60030.1 - 2.2e-161 537.2 0.0 2.6e-161 537.0 0.0 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain SET PF00856.23 AEO60033.1 - 1.2e-07 32.1 0.0 3.6e-06 27.3 0.0 2.1 2 0 0 2 2 2 2 SET domain GatB_N PF02934.10 AEO60034.1 - 1.3e-99 332.6 0.0 1.7e-99 332.3 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 AEO60034.1 - 3.5e-11 43.0 0.0 8.4e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 GatB domain Cu-oxidase PF00394.17 AEO60035.1 - 4.2e-23 81.9 0.2 1.3e-22 80.3 0.1 1.7 1 1 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 AEO60035.1 - 1.4e-13 50.5 3.0 2.2e-12 46.6 0.1 3.0 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 AEO60035.1 - 1.2e-10 41.1 2.9 6.8e-10 38.7 0.7 2.6 2 1 1 3 3 3 1 Multicopper oxidase Asp PF00026.18 AEO60036.1 - 4.6e-22 78.6 0.0 5.3e-20 71.9 0.0 2.2 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 AEO60036.1 - 1.3e-08 34.9 0.1 5.9e-08 32.8 0.0 2.0 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal CRAL_TRIO PF00650.15 AEO60037.1 - 3.9e-15 55.6 0.0 5.5e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 AEO60037.1 - 0.00021 21.3 0.0 0.00054 20.0 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DUF2413 PF10310.4 AEO60037.1 - 3.9 6.1 9.2 5.2 5.7 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) HNH_2 PF13391.1 AEO60038.1 - 3.1e-18 65.2 0.0 4.9e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 HNH endonuclease S4_2 PF13275.1 AEO60038.1 - 0.14 11.7 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 S4 domain Pkinase PF00069.20 AEO60042.1 - 0.00016 20.9 0.0 0.00017 20.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain NRPS PF08415.5 AEO60043.1 - 0.0013 18.4 0.0 0.0058 16.3 0.0 2.2 2 0 0 2 2 2 1 Nonribosomal peptide synthase adh_short PF00106.20 AEO60046.1 - 7e-23 81.3 0.0 2.4e-22 79.5 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO60046.1 - 7.7e-09 35.4 0.0 1.3e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 AEO60046.1 - 9.1e-08 32.1 0.0 1.2e-06 28.4 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 AEO60046.1 - 0.063 12.7 0.0 0.089 12.2 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 AEO60046.1 - 0.077 12.0 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NmrA PF05368.8 AEO60047.1 - 1e-34 119.8 0.0 1.2e-34 119.5 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 AEO60047.1 - 2.9e-10 40.4 0.1 3.9e-10 40.0 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 AEO60047.1 - 0.00018 21.5 0.0 0.00029 20.8 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain Epimerase PF01370.16 AEO60047.1 - 0.00021 20.7 0.0 0.00031 20.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 AEO60047.1 - 0.00041 19.1 0.0 0.00053 18.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 AEO60047.1 - 0.0012 18.7 1.5 0.0021 17.9 1.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Semialdhyde_dh PF01118.19 AEO60047.1 - 0.019 15.3 0.1 0.065 13.5 0.1 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 AEO60047.1 - 0.042 13.5 0.5 0.067 12.8 0.3 1.2 1 0 0 1 1 1 0 KR domain DUF2101 PF09874.4 AEO60051.1 - 3.9 6.9 7.7 1.9 7.9 0.2 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2101) Abhydrolase_6 PF12697.2 AEO60052.1 - 8.8e-28 97.7 3.6 8.8e-27 94.4 2.5 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO60052.1 - 0.00016 21.3 0.0 0.0003 20.4 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AEO60052.1 - 0.00021 21.0 0.0 0.00043 20.0 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 AEO60052.1 - 0.085 11.3 0.0 0.13 10.7 0.0 1.2 1 0 0 1 1 1 0 Ndr family GMC_oxred_C PF05199.8 AEO60053.1 - 2.7e-12 47.1 0.1 3.1e-12 46.9 0.1 1.1 1 0 0 1 1 1 1 GMC oxidoreductase NmrA PF05368.8 AEO60054.1 - 2.9e-11 43.0 0.0 3.7e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 AEO60054.1 - 1.7e-09 37.9 0.0 2.4e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 AEO60054.1 - 1.6e-06 27.3 0.0 2.2e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 AEO60054.1 - 0.0023 18.2 0.3 0.0054 17.0 0.2 1.7 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 AEO60054.1 - 0.0043 16.9 0.1 0.0098 15.8 0.1 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.16 AEO60054.1 - 0.0048 16.3 0.0 0.0073 15.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 AEO60054.1 - 0.0049 17.2 0.3 0.0085 16.4 0.2 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.20 AEO60054.1 - 0.01 15.7 0.1 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase GFO_IDH_MocA PF01408.17 AEO60054.1 - 0.011 16.2 0.1 0.019 15.4 0.0 1.3 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold GARS_N PF02844.10 AEO60054.1 - 0.013 15.9 0.1 0.023 15.1 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain Ldh_1_N PF00056.18 AEO60054.1 - 0.022 14.5 0.1 0.038 13.7 0.1 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain KR PF08659.5 AEO60054.1 - 0.035 13.7 0.1 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 KR domain SKG6 PF08693.5 AEO60055.1 - 0.00038 19.7 0.4 0.00099 18.3 0.3 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Rax2 PF12768.2 AEO60055.1 - 0.17 11.0 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF1469 PF07332.6 AEO60055.1 - 5.9 6.6 8.3 0.24 11.1 1.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) SNF2_N PF00176.18 AEO60058.1 - 1.6e-74 250.3 0.5 3.2e-74 249.4 0.3 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AEO60058.1 - 3.7e-14 52.3 0.0 9.2e-14 51.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AEO60058.1 - 1.2e-08 35.0 0.1 4.3e-08 33.2 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 AEO60058.1 - 6.4e-05 21.9 0.1 0.23 10.2 0.0 2.6 2 0 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 DEAD_2 PF06733.10 AEO60058.1 - 0.14 11.5 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 DEAD_2 NDUF_B8 PF05821.6 AEO60059.1 - 6.2e-05 22.7 0.3 0.0001 22.0 0.2 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Mito_fiss_reg PF05308.6 AEO60060.1 - 0.031 13.6 3.5 0.033 13.5 2.5 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 AEO60060.1 - 0.066 12.4 2.8 0.073 12.3 2.0 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Dscam_C PF12355.3 AEO60060.1 - 2.3 8.5 6.8 2.5 8.3 4.1 1.5 1 1 1 2 2 2 0 Down syndrome cell adhesion molecule C terminal F-box-like PF12937.2 AEO60061.1 - 0.0012 18.5 1.1 0.0017 18.0 0.1 1.9 2 0 0 2 2 2 1 F-box-like CTP_synth_N PF06418.9 AEO60062.1 - 8.3e-100 333.4 0.0 1.2e-99 332.8 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 AEO60062.1 - 2.2e-51 174.0 0.0 3.4e-51 173.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Tannase PF07519.6 AEO60062.1 - 2.9e-40 138.3 0.1 1.2e-33 116.6 0.0 3.0 1 1 1 2 2 2 2 Tannase and feruloyl esterase Peptidase_C26 PF07722.8 AEO60062.1 - 3.3e-05 23.4 0.0 6.3e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 MFS_1 PF07690.11 AEO60063.1 - 6.3e-30 104.0 29.8 6.3e-30 104.0 20.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily p450 PF00067.17 AEO60064.1 - 7.7e-21 74.1 0.0 1.8e-19 69.6 0.0 2.3 2 1 0 2 2 2 2 Cytochrome P450 DUF3439 PF11921.3 AEO60065.1 - 0.079 12.7 3.0 0.17 11.6 2.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) p450 PF00067.17 AEO60067.1 - 2.9e-30 105.2 0.0 7.2e-13 47.8 0.0 3.9 3 1 0 3 3 3 3 Cytochrome P450 p450 PF00067.17 AEO60068.1 - 1.5e-26 92.9 0.0 1.8e-25 89.3 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Cerato-platanin PF07249.7 AEO60070.1 - 6.7e-05 22.8 1.7 6.9e-05 22.8 0.3 1.6 2 0 0 2 2 2 1 Cerato-platanin KorB PF08535.5 AEO60070.1 - 0.027 14.6 0.0 0.058 13.5 0.0 1.5 1 0 0 1 1 1 0 KorB domain rve PF00665.21 AEO60072.1 - 0.0065 16.5 0.0 0.0083 16.2 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain Pkinase PF00069.20 AEO60074.1 - 1.4e-31 109.5 0.0 2.1e-31 109.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO60074.1 - 5.8e-10 38.6 0.0 1.4e-09 37.4 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 AEO60074.1 - 0.0049 16.6 0.1 0.016 14.9 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 AEO60074.1 - 0.005 16.1 0.0 0.0069 15.7 0.0 1.1 1 0 0 1 1 1 1 RIO1 family YrbL-PhoP_reg PF10707.4 AEO60074.1 - 0.021 14.1 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.6 AEO60074.1 - 0.045 12.5 0.0 0.065 12.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.9 AEO60074.1 - 0.078 12.0 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AEO60075.1 - 1.3e-08 34.9 0.3 0.00026 20.7 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 AEO60075.1 - 2.2e-05 23.9 0.0 3.8e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 AEO60075.1 - 0.00098 18.7 0.0 0.071 12.6 0.0 2.2 1 1 1 2 2 2 2 Choline/ethanolamine kinase Pkinase PF00069.20 AEO60075.1 - 0.16 11.0 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Ribonuclease PF00545.15 AEO60078.1 - 3e-17 62.4 0.0 6.1e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 ribonuclease DUF3632 PF12311.3 AEO60079.1 - 2.3e-38 131.8 1.5 3e-38 131.4 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Cas_Csx9 PF09658.5 AEO60079.1 - 0.084 11.6 0.0 0.19 10.4 0.0 1.7 1 1 0 1 1 1 0 CRISPR-associated protein (Cas_Csx9) Clr5 PF14420.1 AEO60080.1 - 2.7e-20 72.0 1.5 5e-20 71.1 1.0 1.5 1 0 0 1 1 1 1 Clr5 domain SNF2_N PF00176.18 AEO60081.1 - 5.8e-09 35.1 0.0 7.4e-08 31.5 0.0 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AEO60081.1 - 1.2e-06 28.2 0.0 2.5e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Ribonuc_2-5A PF06479.7 AEO60082.1 - 5.5e-45 152.3 0.0 9.3e-45 151.6 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.20 AEO60082.1 - 1.9e-44 151.7 0.0 2.9e-44 151.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO60082.1 - 1.3e-22 80.1 0.0 8.5e-22 77.4 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.16 AEO60082.1 - 6.4e-07 28.6 0.2 0.001 18.4 0.0 3.0 2 0 0 2 2 2 2 PQQ enzyme repeat PQQ_2 PF13360.1 AEO60082.1 - 2.3e-05 23.9 0.0 0.00019 20.9 0.0 2.0 1 1 1 2 2 2 2 PQQ-like domain Kdo PF06293.9 AEO60082.1 - 0.00033 19.7 0.0 0.00061 18.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 AEO60082.1 - 0.18 11.1 0.0 0.34 10.2 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL zf-C3HC4_3 PF13920.1 AEO60083.1 - 9.9e-06 25.1 10.5 9.9e-06 25.1 7.3 3.1 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) SWIB PF02201.13 AEO60084.1 - 7.3e-29 99.2 0.8 3.8e-28 96.9 0.2 2.1 2 0 0 2 2 2 1 SWIB/MDM2 domain DEK_C PF08766.6 AEO60084.1 - 1e-17 63.6 1.9 2.4e-17 62.4 1.3 1.7 1 0 0 1 1 1 1 DEK C terminal domain BSP_II PF05432.6 AEO60084.1 - 0.7 9.1 7.1 1.2 8.4 4.9 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Cpn60_TCP1 PF00118.19 AEO60086.1 - 3.6e-134 448.0 9.7 4.3e-134 447.7 6.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PAD_M PF08527.5 AEO60086.1 - 0.018 14.4 0.2 0.58 9.5 0.0 2.3 2 0 0 2 2 2 0 Protein-arginine deiminase (PAD) middle domain eIF2A PF08662.6 AEO60087.1 - 7.9e-40 136.6 4.2 7.6e-38 130.1 0.4 3.9 2 2 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A RRM_6 PF14259.1 AEO60087.1 - 5.4e-05 23.0 0.0 0.00013 21.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 AEO60087.1 - 8e-05 22.3 0.1 0.7 9.8 0.0 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat RRM_5 PF13893.1 AEO60087.1 - 0.00019 21.2 0.0 0.00042 20.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AEO60087.1 - 0.0011 18.5 0.0 0.0026 17.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ORC3_N PF07034.6 AEO60089.1 - 0.3 10.0 1.0 0.5 9.2 0.7 1.3 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus SOBP PF15279.1 AEO60089.1 - 0.34 11.2 4.4 0.55 10.5 3.0 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein DUF4614 PF15391.1 AEO60089.1 - 2.2 8.0 10.3 1.4 8.6 6.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4614) FA_desaturase PF00487.19 AEO60090.1 - 7.5e-29 100.9 22.3 1.2e-28 100.2 15.4 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 AEO60090.1 - 9.8e-09 35.3 0.0 1.8e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) PIG-P PF08510.7 AEO60090.1 - 1.7 8.2 6.2 33 4.1 0.0 2.5 2 0 0 2 2 2 0 PIG-P CVNH PF08881.5 AEO60091.1 - 6.4e-16 58.4 0.0 7.9e-16 58.1 0.0 1.1 1 0 0 1 1 1 1 CVNH domain RabGAP-TBC PF00566.13 AEO60092.1 - 2.5e-28 99.0 0.0 4.2e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF604 PF04646.7 AEO60093.1 - 1.4e-08 34.2 0.0 1.1e-07 31.3 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.11 AEO60093.1 - 0.0016 17.7 0.0 0.0036 16.5 0.0 1.5 1 1 0 1 1 1 1 Fringe-like Fungal_trans PF04082.13 AEO60094.1 - 6.3e-15 54.7 0.0 1e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO60094.1 - 1.2e-05 25.1 12.7 2.5e-05 24.0 8.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_76 PF03663.9 AEO60096.1 - 3.6e-139 464.2 11.4 4.7e-139 463.8 7.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 GSG-1 PF07803.6 AEO60096.1 - 0.022 14.3 0.0 0.57 9.7 0.0 2.5 2 0 0 2 2 2 0 GSG1-like protein CHCH PF06747.8 AEO60097.1 - 1.2e-06 28.2 0.7 2.4e-06 27.2 0.5 1.5 1 1 0 1 1 1 1 CHCH domain DUF1903 PF08991.5 AEO60097.1 - 3.3e-05 23.9 1.7 4.7e-05 23.4 1.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) UPF0203 PF05254.7 AEO60097.1 - 0.02 14.7 3.5 0.07 12.9 1.6 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) NatB_MDM20 PF09797.4 AEO60098.1 - 3.1e-91 305.8 0.0 1.5e-90 303.5 0.0 2.1 3 0 0 3 3 3 1 N-acetyltransferase B complex (NatB) non catalytic subunit APC_basic PF05956.6 AEO60098.1 - 0.76 8.8 7.8 0.093 11.8 1.9 1.7 1 1 0 2 2 2 0 APC basic domain Ilm1 PF10311.4 AEO60099.1 - 6.8e-59 198.0 0.3 1.1e-58 197.3 0.2 1.3 1 1 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 Prenyltrans PF00432.16 AEO60100.1 - 1.4e-35 120.5 19.3 4.2e-11 42.2 0.1 6.8 7 1 0 7 7 7 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 AEO60100.1 - 4.1e-21 75.5 0.2 9.2e-12 45.3 0.2 3.4 2 1 1 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 AEO60100.1 - 3.5e-08 33.4 0.2 0.00082 19.3 0.1 3.8 3 1 0 3 3 3 2 Prenyltransferase-like A2M_comp PF07678.9 AEO60100.1 - 0.17 11.0 0.0 7.8 5.6 0.0 2.7 3 0 0 3 3 3 0 A-macroglobulin complement component M20_dimer PF07687.9 AEO60101.1 - 1.7e-20 72.7 0.1 3.5e-20 71.8 0.1 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 AEO60101.1 - 6.7e-18 64.8 0.0 9.1e-18 64.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 IF-2B PF01008.12 AEO60102.1 - 1.6e-72 243.8 0.4 1.9e-72 243.6 0.3 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family TRAPPC10 PF12584.3 AEO60103.1 - 2.2e-24 85.6 0.0 3.7e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 C2 PF00168.25 AEO60104.1 - 1.9e-10 40.4 0.0 3.1e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 C2 domain Pkinase PF00069.20 AEO60105.1 - 1.9e-69 233.7 0.0 2.8e-69 233.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO60105.1 - 2.9e-43 147.7 0.0 4.2e-43 147.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO60105.1 - 3.9e-10 39.1 0.0 1.6e-08 33.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 AEO60105.1 - 0.00081 18.5 0.1 0.002 17.2 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AEO60105.1 - 0.023 14.4 2.6 1.3 8.6 0.1 3.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family Evr1_Alr PF04777.8 AEO60107.1 - 5.5e-27 93.5 0.5 9.5e-27 92.7 0.4 1.4 1 1 0 1 1 1 1 Erv1 / Alr family Proteasome PF00227.21 AEO60108.1 - 9.3e-49 165.3 0.1 1.1e-48 165.0 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit Cyclin PF08613.6 AEO60111.1 - 1.7e-38 132.3 0.9 7.3e-23 81.6 0.1 2.4 2 0 0 2 2 2 2 Cyclin Nop14 PF04147.7 AEO60111.1 - 0.21 9.4 4.4 0.32 8.8 3.0 1.2 1 0 0 1 1 1 0 Nop14-like family CDK5_activator PF03261.10 AEO60111.1 - 0.81 8.9 4.6 2.2 7.5 3.2 1.7 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Sugar_tr PF00083.19 AEO60112.1 - 3.2e-88 296.3 25.7 4e-88 295.9 17.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO60112.1 - 5.2e-15 55.0 42.4 7.8e-09 34.6 9.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3445 PF11927.3 AEO60114.1 - 1.2e-71 241.0 0.0 1.5e-71 240.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Abhydrolase_5 PF12695.2 AEO60115.1 - 0.00021 21.0 0.3 0.0012 18.5 0.2 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AEO60115.1 - 0.01 15.7 2.4 0.053 13.3 1.6 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 AEO60115.1 - 0.019 14.1 0.0 0.035 13.3 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF3336 PF11815.3 AEO60116.1 - 2.7e-41 140.4 1.2 4.5e-41 139.7 0.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 AEO60116.1 - 9.4e-22 77.9 0.0 1.8e-21 76.9 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase adh_short PF00106.20 AEO60117.1 - 1.3e-30 106.5 0.0 1.7e-30 106.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO60117.1 - 1.5e-11 44.3 0.0 2.3e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 AEO60117.1 - 2.4e-06 27.1 0.0 3.2e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 AEO60117.1 - 2.7e-06 27.3 0.0 3.9e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PALP PF00291.20 AEO60117.1 - 0.039 13.1 0.0 0.056 12.6 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme 2-Hacid_dh_C PF02826.14 AEO60117.1 - 0.15 11.2 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.22 AEO60118.1 - 3.7e-13 49.6 2.2 2.2e-12 47.2 0.1 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AEO60118.1 - 1.2e-06 28.7 0.0 0.00073 19.6 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 AEO60118.1 - 1.4e-06 28.3 0.1 0.025 14.4 0.0 3.2 2 2 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 AEO60118.1 - 0.00026 20.0 0.1 0.0015 17.5 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 AEO60118.1 - 0.00038 19.6 0.6 0.014 14.5 0.0 2.7 3 0 0 3 3 3 1 FAD binding domain Lycopene_cycl PF05834.7 AEO60118.1 - 0.0023 16.8 0.0 0.0036 16.2 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 AEO60118.1 - 0.0078 15.1 0.2 0.019 13.8 0.2 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 AEO60118.1 - 0.028 13.0 0.0 0.24 9.9 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.1 AEO60118.1 - 0.33 10.7 1.8 8.6 6.1 0.0 3.0 2 1 0 3 3 3 0 FAD-NAD(P)-binding Acetyltransf_8 PF13523.1 AEO60119.1 - 6.2e-42 143.0 0.6 8.9e-42 142.5 0.4 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 AEO60119.1 - 0.0018 18.4 0.1 0.0038 17.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AMP-binding PF00501.23 AEO60120.1 - 4.9e-93 311.7 0.0 6.2e-93 311.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 AEO60120.1 - 2.7e-13 50.6 0.9 6.5e-13 49.4 0.1 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF3409 PF11889.3 AEO60120.1 - 0.16 11.6 0.0 27 4.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3409) Sulfatase PF00884.18 AEO60121.1 - 1.6e-62 211.4 0.2 2e-62 211.1 0.2 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 AEO60121.1 - 0.01 15.1 0.1 1 8.6 0.0 2.2 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase MFS_1 PF07690.11 AEO60122.1 - 3.2e-39 134.6 46.1 8.5e-31 106.9 18.9 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO60122.1 - 3.1e-14 52.4 25.6 4.3e-13 48.6 6.2 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 AEO60122.1 - 1.4e-11 43.3 17.4 3.2e-11 42.1 12.0 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Phage_holin_2 PF04550.7 AEO60122.1 - 0.0073 16.3 1.7 0.029 14.4 1.2 2.0 1 0 0 1 1 1 1 Phage holin family 2 Kelch_4 PF13418.1 AEO60123.1 - 3e-20 71.7 0.1 9.5e-10 38.1 0.0 5.3 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.1 AEO60123.1 - 1.4e-19 69.6 5.8 5.5e-11 42.3 0.0 6.2 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.1 AEO60123.1 - 6.4e-13 48.2 1.7 3.2e-05 23.9 0.1 4.9 3 1 1 4 4 4 2 Kelch motif Kelch_5 PF13854.1 AEO60123.1 - 9.1e-13 47.8 2.9 4.1e-06 26.6 0.0 4.3 3 1 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 AEO60123.1 - 1.2e-10 40.7 0.1 0.00097 18.6 0.0 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.10 AEO60123.1 - 1e-08 34.5 0.1 0.0001 21.8 0.0 4.6 4 1 0 4 4 4 1 Kelch motif BTB PF00651.26 AEO60123.1 - 0.0044 16.9 0.0 0.052 13.5 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain AhpC-TSA PF00578.16 AEO60124.1 - 2.7e-32 111.0 0.0 3.6e-32 110.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.4 AEO60124.1 - 4.5e-12 45.4 0.2 8.8e-12 44.4 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 AEO60124.1 - 4.2e-11 42.5 0.0 5.4e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin AMP-binding PF00501.23 AEO60125.1 - 3.3e-75 253.0 0.0 4.5e-75 252.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 AEO60125.1 - 9.8e-10 39.2 0.7 2.5e-09 37.9 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PIG-S PF10510.4 AEO60126.1 - 4e-153 510.8 0.0 4.5e-153 510.6 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Acetyltransf_1 PF00583.19 AEO60127.1 - 1e-10 41.5 0.0 1.7e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AEO60127.1 - 1.6e-05 24.9 0.0 2.5e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 AEO60127.1 - 5.1e-05 22.9 0.0 0.00012 21.7 0.0 1.7 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 AEO60127.1 - 0.00013 22.0 0.0 0.0002 21.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 AEO60127.1 - 0.059 13.5 0.0 0.098 12.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosomal_L36 PF00444.13 AEO60128.1 - 0.00012 22.0 7.2 0.00014 21.8 4.3 1.6 2 0 0 2 2 2 1 Ribosomal protein L36 MAP65_ASE1 PF03999.7 AEO60128.1 - 0.11 11.1 2.4 0.11 11.1 1.7 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Complex1_LYR_1 PF13232.1 AEO60129.1 - 9.3e-18 64.1 0.3 9.3e-18 64.1 0.2 1.6 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR PF05347.10 AEO60129.1 - 5.6e-17 61.2 0.3 9e-17 60.6 0.2 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 AEO60129.1 - 0.00041 20.7 0.1 0.00068 20.0 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like YfbU PF03887.9 AEO60129.1 - 0.017 14.6 0.0 0.018 14.5 0.0 1.1 1 0 0 1 1 1 0 YfbU domain GMC_oxred_N PF00732.14 AEO60130.1 - 2.6e-61 207.3 0.0 3.3e-61 207.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 AEO60130.1 - 5.8e-34 117.4 0.0 9.5e-34 116.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 AEO60130.1 - 1e-05 24.6 0.1 0.00098 18.1 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 AEO60130.1 - 4.4e-05 22.5 2.0 0.0026 16.7 0.4 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 AEO60130.1 - 8.1e-05 22.5 0.3 0.00022 21.2 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 AEO60130.1 - 0.00012 21.9 0.8 0.0066 16.3 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AEO60130.1 - 0.00042 20.4 0.2 0.83 9.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 AEO60130.1 - 0.001 18.0 0.2 0.0016 17.4 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 AEO60130.1 - 0.0012 17.3 0.3 0.037 12.5 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 AEO60130.1 - 0.014 14.5 0.4 0.048 12.7 0.1 1.9 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.1 AEO60130.1 - 0.1 12.3 0.9 0.31 10.8 0.1 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding TrkA_N PF02254.13 AEO60130.1 - 0.11 12.5 0.3 0.28 11.1 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain Trp_halogenase PF04820.9 AEO60130.1 - 0.14 10.7 0.3 0.2 10.2 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase MHC_I_C PF06623.6 AEO60131.1 - 0.17 11.4 1.2 0.3 10.5 0.8 1.4 1 0 0 1 1 1 0 MHC_I C-terminus CTP_transf_2 PF01467.21 AEO60132.1 - 0.00012 22.1 0.6 0.0013 18.8 0.4 2.4 1 1 0 1 1 1 1 Cytidylyltransferase WD40 PF00400.27 AEO60133.1 - 1.3e-21 75.5 10.5 7.3e-09 35.1 0.0 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat Collagen PF01391.13 AEO60133.1 - 0.017 14.6 3.6 0.017 14.6 2.5 3.3 3 0 0 3 3 3 0 Collagen triple helix repeat (20 copies) EF1_GNE PF00736.14 AEO60134.1 - 2.5e-31 107.2 1.7 4.2e-31 106.5 1.2 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 AEO60134.1 - 1.5e-13 50.6 8.0 4.1e-13 49.2 5.6 1.8 1 0 0 1 1 1 1 Eukaryotic elongation factor 1 beta central acidic region GST_C PF00043.20 AEO60134.1 - 0.00077 19.3 0.5 0.0025 17.7 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 AEO60134.1 - 0.0053 17.2 0.0 0.011 16.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain KCl_Cotrans_1 PF03522.10 AEO60134.1 - 0.11 12.0 0.1 0.28 10.7 0.1 1.6 1 0 0 1 1 1 0 K-Cl Co-transporter type 1 (KCC1) Translin PF01997.11 AEO60135.1 - 1.6e-67 227.0 0.0 1.8e-67 226.7 0.0 1.0 1 0 0 1 1 1 1 Translin family NPV_P10 PF05531.7 AEO60135.1 - 0.046 13.9 0.1 0.12 12.6 0.1 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Mannosyl_trans PF05007.8 AEO60136.1 - 1.7e-17 63.9 0.3 2.6e-17 63.3 0.2 1.3 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 AEO60136.1 - 4e-11 42.3 3.5 5.3e-11 42.0 2.4 1.2 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U DUF2029 PF09594.5 AEO60136.1 - 1.1e-05 25.1 9.3 1.1e-05 25.1 6.5 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF2029) CD24 PF14984.1 AEO60136.1 - 1.2 8.9 7.2 0.43 10.4 2.4 2.3 2 0 0 2 2 2 0 CD24 protein F-box-like PF12937.2 AEO60137.1 - 5.3e-06 26.0 0.2 3e-05 23.6 0.2 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 AEO60137.1 - 0.002 17.7 0.9 0.98 9.1 0.1 3.5 3 0 0 3 3 3 2 F-box domain Peptidase_S8 PF00082.17 AEO60138.1 - 1.9e-46 158.5 12.6 1.9e-46 158.5 8.7 1.4 2 0 0 2 2 2 1 Subtilase family Inhibitor_I9 PF05922.11 AEO60138.1 - 5.3e-05 23.7 0.3 9.7e-05 22.8 0.2 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 SQS_PSY PF00494.14 AEO60139.1 - 3.7e-38 131.3 0.0 7.6e-38 130.3 0.0 1.5 2 0 0 2 2 2 1 Squalene/phytoene synthase RmlD_sub_bind PF04321.12 AEO60140.1 - 2.7e-14 52.7 0.0 6.4e-14 51.5 0.0 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 AEO60140.1 - 2e-13 50.3 0.0 3.8e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 AEO60140.1 - 0.00033 19.6 0.0 0.00061 18.7 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DnaJ-X PF14308.1 AEO60141.1 - 5.8e-71 237.9 1.5 5.8e-71 237.9 1.1 2.2 3 0 0 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.26 AEO60141.1 - 1.2e-27 95.3 1.0 2.5e-27 94.3 0.7 1.6 1 0 0 1 1 1 1 DnaJ domain SUZ PF12752.2 AEO60141.1 - 0.064 13.7 10.0 0.041 14.4 3.3 3.0 2 0 0 2 2 2 0 SUZ domain Tnp_P_element PF12017.3 AEO60142.1 - 0.0081 15.4 2.0 0.066 12.4 0.5 2.1 2 0 0 2 2 2 2 Transposase protein Cyt-b5 PF00173.23 AEO60143.1 - 4e-16 58.5 0.0 5.9e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FHA PF00498.21 AEO60144.1 - 0.0019 18.2 0.1 0.0042 17.1 0.1 1.6 1 0 0 1 1 1 1 FHA domain BRCT PF00533.21 AEO60144.1 - 0.0072 16.4 0.1 0.074 13.2 0.0 2.4 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Abhydrolase_4 PF08386.5 AEO60145.1 - 4.7e-16 58.5 0.0 9.7e-16 57.5 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 AEO60145.1 - 4.2e-08 33.0 0.2 9.9e-05 21.9 0.0 2.8 2 2 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 AEO60145.1 - 5.5e-08 32.9 8.3 9.9e-07 28.8 5.7 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO60145.1 - 0.00023 20.9 0.1 0.0011 18.7 0.1 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family MARVEL PF01284.18 AEO60146.1 - 1.5e-16 60.5 24.1 1.8e-16 60.2 16.7 1.1 1 0 0 1 1 1 1 Membrane-associating domain Ribosomal_S5 PF00333.15 AEO60147.1 - 3.5e-28 97.1 2.4 3.5e-28 97.1 1.7 1.6 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 AEO60147.1 - 4.6e-20 70.6 0.0 4.6e-20 70.6 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Grp1_Fun34_YaaH PF01184.14 AEO60148.1 - 1e-88 296.1 14.4 1.2e-88 295.8 10.0 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Fungal_trans PF04082.13 AEO60149.1 - 2.5e-15 56.0 0.3 3.8e-15 55.4 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO60149.1 - 1.3e-06 28.1 13.0 2.3e-06 27.3 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHquinase_I PF01487.10 AEO60150.1 - 1.2e-40 139.5 0.0 2.2e-40 138.6 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.6 AEO60150.1 - 2.5e-21 75.4 0.1 6e-21 74.2 0.1 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SKI PF01202.17 AEO60150.1 - 1.6e-16 60.5 0.0 2.8e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Shikimate kinase Shikimate_DH PF01488.15 AEO60150.1 - 1e-11 45.0 0.0 2.9e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_17 PF13207.1 AEO60150.1 - 0.0043 17.8 0.0 0.0096 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 AEO60150.1 - 0.026 13.6 0.1 0.047 12.7 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 AEO60150.1 - 0.045 14.0 0.0 0.083 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 AEO60150.1 - 0.081 12.8 0.1 0.59 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain Sugar_tr PF00083.19 AEO60151.1 - 8.6e-133 443.1 23.0 9.8e-133 443.0 15.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO60151.1 - 1.5e-25 89.6 41.7 1.7e-25 89.4 23.9 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Shikimate_dh_N PF08501.6 AEO60152.1 - 4.3e-21 74.7 0.0 7.6e-21 73.9 0.0 1.4 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 AEO60152.1 - 1.9e-13 50.6 0.0 3.1e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 AEO60152.1 - 0.01 14.8 0.0 0.013 14.4 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase AP_endonuc_2 PF01261.19 AEO60153.1 - 1.5e-32 112.6 0.0 1.9e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DHquinase_II PF01220.14 AEO60154.1 - 9.7e-57 190.2 0.2 3.9e-56 188.2 0.1 1.7 1 1 0 1 1 1 1 Dehydroquinase class II Inositol_P PF00459.20 AEO60155.1 - 2.9e-76 256.3 0.0 3.4e-76 256.1 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family WD40 PF00400.27 AEO60156.1 - 3.9e-06 26.5 2.5 0.016 15.1 0.5 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat Nucleoplasmin PF03066.10 AEO60156.1 - 0.02 14.4 2.9 0.036 13.5 2.0 1.3 1 0 0 1 1 1 0 Nucleoplasmin CDC45 PF02724.9 AEO60156.1 - 0.04 11.9 3.9 0.053 11.5 2.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 AEO60156.1 - 0.25 9.2 5.4 0.32 8.8 3.7 1.1 1 0 0 1 1 1 0 Nop14-like family PQQ_3 PF13570.1 AEO60156.1 - 0.43 10.9 5.3 33 4.9 0.4 4.1 2 1 0 3 3 3 0 PQQ-like domain PBP1_TM PF14812.1 AEO60156.1 - 5.1 7.4 8.6 11 6.4 6.0 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Glyco_hydro_18 PF00704.23 AEO60157.1 - 3.4e-43 148.4 0.0 4.1e-43 148.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Abhydrolase_6 PF12697.2 AEO60158.1 - 2.6e-32 112.5 1.5 3.2e-32 112.2 1.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO60158.1 - 5e-14 52.4 0.1 2.4e-13 50.2 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AEO60158.1 - 2.2e-09 37.2 0.0 1.1e-08 34.9 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 AEO60158.1 - 0.00035 20.3 0.0 0.00087 19.0 0.0 1.8 1 0 0 1 1 1 1 Putative lysophospholipase Rhodanese PF00581.15 AEO60159.1 - 6.6e-19 68.3 0.0 5e-10 39.7 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain Peptidase_M24 PF00557.19 AEO60159.1 - 0.16 11.5 0.2 0.62 9.6 0.1 1.8 1 1 1 2 2 2 0 Metallopeptidase family M24 zf-Apc11 PF12861.2 AEO60160.1 - 4e-45 151.5 10.8 4.8e-45 151.3 7.5 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 AEO60160.1 - 2.2e-33 114.1 9.8 2.9e-33 113.8 6.8 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 AEO60160.1 - 2.6e-08 33.5 17.2 2.1e-07 30.6 11.9 2.4 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 AEO60160.1 - 5.1e-05 23.2 12.9 0.00032 20.6 8.9 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AEO60160.1 - 9.3e-05 22.0 14.4 0.00046 19.7 10.0 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AEO60160.1 - 0.00026 20.6 12.4 0.0084 15.7 8.6 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 AEO60160.1 - 0.00029 20.6 3.9 0.00029 20.6 2.7 2.4 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 AEO60160.1 - 0.0011 18.3 5.4 0.0019 17.6 3.7 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 AEO60160.1 - 0.0025 17.3 3.3 0.0025 17.3 2.3 2.3 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.1 AEO60160.1 - 0.013 15.1 16.1 0.23 11.1 11.4 2.5 1 1 1 2 2 2 0 zinc-RING finger domain FANCL_C PF11793.3 AEO60160.1 - 0.026 14.5 17.2 0.61 10.0 11.9 3.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-DBF PF07535.7 AEO60160.1 - 0.029 14.0 0.3 0.79 9.4 0.0 2.2 2 0 0 2 2 2 0 DBF zinc finger MR_MLE PF01188.16 AEO60160.1 - 0.11 13.0 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain zf-RING_UBOX PF13445.1 AEO60160.1 - 1 9.1 8.2 0.65 9.7 4.0 2.1 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING-like PF08746.6 AEO60160.1 - 1.6 8.8 13.6 8.2 6.5 9.4 2.1 1 1 0 1 1 1 0 RING-like domain Opy2 PF09463.5 AEO60160.1 - 1.8 8.6 11.1 13 6.0 4.7 2.3 2 0 0 2 2 2 0 Opy2 protein RINGv PF12906.2 AEO60160.1 - 2.3 8.3 12.5 8.2 6.5 8.5 2.2 1 1 0 1 1 1 0 RING-variant domain DUF393 PF04134.7 AEO60160.1 - 5.1 8.2 8.1 16 6.6 0.1 2.7 3 0 0 3 3 2 0 Protein of unknown function, DUF393 zf-HC5HC2H_2 PF13832.1 AEO60160.1 - 6.4 6.8 10.0 4.1 7.4 4.0 2.2 1 1 1 2 2 2 0 PHD-zinc-finger like domain Syntaxin PF00804.20 AEO60162.1 - 1.3e-07 31.7 2.4 1.3e-07 31.7 1.6 2.8 2 1 1 3 3 3 1 Syntaxin DUF1183 PF06682.7 AEO60162.1 - 0.00024 20.8 1.3 0.00054 19.6 0.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) DUF1510 PF07423.6 AEO60162.1 - 0.00045 19.6 0.5 0.0011 18.4 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1510) Rifin_STEVOR PF02009.11 AEO60162.1 - 0.0024 17.5 3.4 0.0024 17.5 2.4 1.7 1 1 0 1 1 1 1 Rifin/stevor family P12 PF12669.2 AEO60162.1 - 0.0033 17.6 0.1 0.0057 16.8 0.1 1.3 1 0 0 1 1 1 1 Virus attachment protein p12 family SpoIIIAH PF12685.2 AEO60162.1 - 0.006 16.0 0.1 0.006 16.0 0.1 2.8 2 1 1 3 3 2 1 SpoIIIAH-like protein SNARE PF05739.14 AEO60162.1 - 0.011 15.4 8.3 0.011 15.4 5.7 3.3 3 1 1 4 4 4 0 SNARE domain GRA6 PF05084.8 AEO60162.1 - 0.013 15.0 7.6 0.016 14.7 3.7 2.3 1 1 1 2 2 2 0 Granule antigen protein (GRA6) TBPIP PF07106.8 AEO60162.1 - 0.024 14.2 11.9 0.15 11.5 1.7 2.5 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DASH_Dad3 PF08656.5 AEO60162.1 - 0.027 14.1 1.9 3 7.6 0.1 3.1 3 0 0 3 3 3 0 DASH complex subunit Dad3 Med7 PF05983.6 AEO60162.1 - 0.062 13.0 2.2 0.24 11.1 0.1 2.3 2 0 0 2 2 2 0 MED7 protein Synaptobrevin PF00957.16 AEO60162.1 - 0.14 11.7 7.4 0.12 12.0 2.1 2.8 2 0 0 2 2 2 0 Synaptobrevin Spc7 PF08317.6 AEO60162.1 - 0.62 8.6 14.9 1.1 7.8 2.6 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Syntaxin_2 PF14523.1 AEO60162.1 - 1.3 9.0 7.9 0.34 10.9 1.6 2.7 2 1 0 2 2 2 0 Syntaxin-like protein LXG PF04740.7 AEO60162.1 - 1.3 8.7 11.9 0.18 11.5 1.3 2.3 1 1 0 2 2 2 0 LXG domain of WXG superfamily DUF912 PF06024.7 AEO60162.1 - 4.3 7.4 11.4 0.37 10.8 0.1 2.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) LMBR1 PF04791.11 AEO60162.1 - 4.7 5.6 7.2 0.096 11.2 0.3 1.6 2 1 0 2 2 2 0 LMBR1-like membrane protein YlqD PF11068.3 AEO60162.1 - 5.5 7.0 20.9 9e+02 -0.2 14.5 2.8 1 1 0 1 1 1 0 YlqD protein CDC37_N PF03234.9 AEO60162.1 - 6.2 7.1 12.0 10 6.4 1.5 2.3 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding Memo PF01875.12 AEO60163.1 - 3.9e-77 258.8 0.0 4.4e-77 258.6 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein FYVE PF01363.16 AEO60164.1 - 0.062 13.1 8.2 0.21 11.5 5.6 1.8 1 1 0 1 1 1 0 FYVE zinc finger C6_DPF PF10170.4 AEO60164.1 - 0.16 11.9 1.7 0.37 10.8 1.1 1.5 1 0 0 1 1 1 0 Cysteine-rich domain DUF508 PF04370.7 AEO60164.1 - 0.24 11.0 0.0 0.24 11.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF508) FYVE_2 PF02318.11 AEO60164.1 - 1 9.2 6.6 0.28 11.1 2.4 1.5 1 1 0 1 1 1 0 FYVE-type zinc finger zf-C2H2_6 PF13912.1 AEO60164.1 - 5.9 6.9 8.5 1.1 9.2 2.1 2.6 2 1 0 2 2 2 0 C2H2-type zinc finger zf-C3HC4_2 PF13923.1 AEO60164.1 - 9.5 6.3 11.1 1 9.4 4.2 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) IMS PF00817.15 AEO60165.1 - 5.8e-44 149.4 0.1 1.2e-43 148.4 0.1 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 AEO60165.1 - 3.6e-16 59.2 0.1 8.2e-16 58.0 0.1 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 AEO60165.1 - 2.9e-05 23.8 0.0 9.6e-05 22.2 0.0 2.0 1 0 0 1 1 1 1 IMS family HHH motif FKBP_C PF00254.23 AEO60166.1 - 1.2e-31 108.5 0.0 1.7e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase RPEL PF02755.10 AEO60168.1 - 2.5e-21 74.3 1.9 1.8e-10 39.8 0.0 2.6 3 0 0 3 3 3 2 RPEL repeat TLD PF07534.11 AEO60169.1 - 3.1e-30 104.9 0.0 1.1e-29 103.2 0.0 1.8 1 1 0 1 1 1 1 TLD MUG2_C PF08593.5 AEO60169.1 - 2.8e-10 40.2 0.4 1.2e-09 38.2 0.3 2.1 2 0 0 2 2 2 1 Meiotically up-regulated glycoproteins C-terminal Poty_coat PF00767.13 AEO60169.1 - 0.065 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Potyvirus coat protein HIG_1_N PF04588.8 AEO60170.1 - 1.6e-23 82.1 0.8 1.6e-23 82.1 0.6 1.9 2 0 0 2 2 2 1 Hypoxia induced protein conserved region Selenoprotein_S PF06936.6 AEO60170.1 - 0.0018 17.8 3.8 0.0026 17.3 2.6 1.2 1 0 0 1 1 1 1 Selenoprotein S (SelS) DUF2611 PF11022.3 AEO60170.1 - 0.0031 17.5 0.7 0.28 11.2 0.1 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF2611) DUF2514 PF10721.4 AEO60170.1 - 0.047 13.3 13.6 0.069 12.8 9.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) CD34_antigen PF06365.7 AEO60170.1 - 0.062 12.9 0.3 0.25 10.9 0.0 2.0 1 1 1 2 2 2 0 CD34/Podocalyxin family Herpes_UL17 PF04559.7 AEO60170.1 - 0.11 11.1 1.5 0.12 10.8 1.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL17 protein Myelin_MBP PF01669.12 AEO60170.1 - 0.13 12.5 4.5 0.27 11.4 0.1 2.3 1 1 1 2 2 2 0 Myelin basic protein SDP_N PF12278.3 AEO60170.1 - 0.19 11.3 6.2 0.29 10.7 4.3 1.2 1 0 0 1 1 1 0 Sex determination protein N terminal RRS1 PF04939.7 AEO60170.1 - 0.34 10.3 8.2 0.58 9.6 5.7 1.3 1 0 0 1 1 1 0 Ribosome biogenesis regulatory protein (RRS1) Lentiviral_Tat PF02998.9 AEO60170.1 - 0.45 10.3 4.1 0.87 9.4 2.9 1.4 1 0 0 1 1 1 0 Lentiviral Tat protein Menin PF05053.8 AEO60170.1 - 0.48 8.5 4.0 0.59 8.2 2.7 1.1 1 0 0 1 1 1 0 Menin RRP14 PF15459.1 AEO60170.1 - 1.3 9.1 7.9 9.1 6.4 0.3 2.7 2 0 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 PALP PF00291.20 AEO60171.1 - 2.5e-75 253.5 0.9 3.1e-75 253.2 0.6 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 AEO60171.1 - 2.2e-40 136.1 0.0 2e-21 75.3 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase 2-oxoacid_dh PF00198.18 AEO60173.1 - 1.6e-81 272.9 0.1 2.3e-81 272.4 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 AEO60173.1 - 2.1e-17 62.5 1.4 2.1e-17 62.5 0.9 1.7 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 AEO60173.1 - 0.0042 16.7 0.4 0.053 13.2 0.1 2.3 1 1 1 2 2 2 1 Biotin-lipoyl like DUF3614 PF12267.3 AEO60173.1 - 0.026 14.7 0.5 0.15 12.3 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3614) HlyD_3 PF13437.1 AEO60173.1 - 0.034 14.4 0.2 0.66 10.3 0.1 2.3 1 1 1 2 2 2 0 HlyD family secretion protein YL1 PF05764.8 AEO60173.1 - 0.5 9.9 9.6 0.74 9.3 6.7 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Neisseria_TspB PF05616.8 AEO60173.1 - 7.2 4.8 15.4 10 4.3 10.7 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein RR_TM4-6 PF06459.7 AEO60173.1 - 7.7 6.3 10.5 11 5.8 7.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Complex1_LYR PF05347.10 AEO60174.1 - 1.1e-10 41.1 2.5 1.5e-10 40.7 1.8 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 AEO60174.1 - 3.9e-08 33.3 1.3 5.5e-08 32.9 0.9 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Histone PF00125.19 AEO60175.1 - 8.4e-26 89.8 0.0 1.1e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 AEO60175.1 - 1.3e-05 25.2 0.0 1.7e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 AEO60176.1 - 9.3e-22 76.9 0.2 1.3e-21 76.4 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 AEO60176.1 - 4.6e-05 23.3 0.5 9.9e-05 22.3 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 AEO60176.1 - 0.00021 21.5 0.0 0.00036 20.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.8 AEO60176.1 - 0.025 14.0 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 Replication protein C N-terminal domain Mitofilin PF09731.4 AEO60176.1 - 0.032 12.9 2.1 0.041 12.5 1.5 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF1018 PF06252.7 AEO60176.1 - 0.032 14.7 0.3 0.043 14.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) G-patch PF01585.18 AEO60177.1 - 2.8e-12 46.2 2.4 5.5e-12 45.2 1.7 1.5 1 0 0 1 1 1 1 G-patch domain R3H PF01424.17 AEO60177.1 - 4.8e-12 45.3 0.0 4.8e-12 45.3 0.0 1.8 2 0 0 2 2 2 1 R3H domain G-patch_2 PF12656.2 AEO60177.1 - 0.0035 17.1 1.9 0.0035 17.1 1.3 2.9 3 0 0 3 3 3 1 DExH-box splicing factor binding site TIP_N PF12457.3 AEO60177.1 - 0.8 9.8 0.0 0.8 9.8 0.0 3.9 4 0 0 4 4 4 0 Tuftelin interacting protein N terminal Peptidase_C54 PF03416.14 AEO60178.1 - 2.1e-96 322.3 0.0 2.5e-96 322.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 DnaJ PF00226.26 AEO60179.1 - 9e-26 89.4 0.3 3e-25 87.7 0.2 2.0 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.3 AEO60179.1 - 1.4e-10 40.9 2.6 2.9e-10 39.9 1.8 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 AEO60179.1 - 2e-09 37.2 2.5 4.1e-09 36.3 1.7 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 AEO60179.1 - 3.7e-05 23.7 0.6 7e-05 22.8 0.4 1.4 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 AEO60179.1 - 0.019 15.2 0.7 0.045 14.1 0.5 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF2387 PF09526.5 AEO60179.1 - 0.046 13.6 2.5 0.14 12.0 1.7 1.8 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) Lact-deh-memb PF09330.6 AEO60179.1 - 0.061 12.7 0.8 0.089 12.1 0.6 1.2 1 0 0 1 1 1 0 D-lactate dehydrogenase, membrane binding RPT PF13446.1 AEO60179.1 - 0.072 12.4 0.0 0.37 10.2 0.0 2.1 2 0 0 2 2 2 0 A repeated domain in UCH-protein zf-C2H2_4 PF13894.1 AEO60179.1 - 0.076 13.3 0.5 0.21 12.0 0.3 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_6 PF13912.1 AEO60179.1 - 0.13 12.1 0.9 0.27 11.1 0.6 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger Neur_chan_memb PF02932.11 AEO60179.1 - 1.9 8.3 5.1 3.9 7.2 3.5 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SPX PF03105.14 AEO60180.1 - 6.7e-38 131.0 0.3 8.9e-38 130.6 0.2 1.2 1 0 0 1 1 1 1 SPX domain zf-C3HC4 PF00097.20 AEO60180.1 - 1.1e-05 24.9 14.8 2e-05 24.1 10.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AEO60180.1 - 2.8e-05 23.8 14.0 4.9e-05 23.0 9.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 AEO60180.1 - 4.6e-05 22.9 10.8 7.6e-05 22.3 7.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 AEO60180.1 - 0.00028 20.7 13.7 0.00048 19.9 9.5 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 AEO60180.1 - 0.0051 16.5 12.2 0.012 15.3 8.5 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 AEO60180.1 - 0.0058 16.6 15.5 0.01 15.8 10.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 AEO60180.1 - 0.043 13.4 4.9 0.1 12.2 3.4 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DZR PF12773.2 AEO60180.1 - 1.1 9.1 6.0 2.3 8.1 4.2 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-RING_UBOX PF13445.1 AEO60180.1 - 2 8.1 10.2 5.5 6.8 7.0 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Cys_Met_Meta_PP PF01053.15 AEO60181.1 - 4.7e-34 117.3 0.0 6.3e-34 116.8 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 AEO60181.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Gly-zipper_OmpA PF13436.1 AEO60182.1 - 0.17 11.5 3.1 0.24 11.0 1.0 2.0 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Strabismus PF06638.6 AEO60182.1 - 1.2 7.3 3.5 1.8 6.7 2.5 1.2 1 0 0 1 1 1 0 Strabismus protein EMG1 PF03587.9 AEO60183.1 - 9.7e-78 260.0 0.0 1.1e-77 259.8 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase PH PF00169.24 AEO60184.1 - 5.8e-11 42.5 0.1 1.3e-10 41.4 0.1 1.6 1 0 0 1 1 1 1 PH domain Prominin PF05478.6 AEO60184.1 - 0.00049 17.7 0.6 0.00074 17.1 0.4 1.2 1 0 0 1 1 1 1 Prominin Baculo_PEP_C PF04513.7 AEO60184.1 - 0.26 11.1 1.4 1.1 9.0 0.2 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Gar1 PF04410.9 AEO60185.1 - 3.7e-44 149.9 0.3 3.7e-44 149.9 0.2 1.7 1 1 1 2 2 2 1 Gar1/Naf1 RNA binding region DnaJ PF00226.26 AEO60186.1 - 1.3e-23 82.4 5.0 1.4e-23 82.3 1.3 2.6 2 0 0 2 2 2 1 DnaJ domain TPR_11 PF13414.1 AEO60186.1 - 2.8e-20 71.7 15.6 2e-08 33.7 0.0 5.3 2 1 5 7 7 7 6 TPR repeat TPR_2 PF07719.12 AEO60186.1 - 1.6e-17 61.9 17.6 0.014 15.3 0.2 8.0 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_1 PF00515.23 AEO60186.1 - 3.6e-16 58.0 10.3 0.0004 19.8 0.0 7.3 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 AEO60186.1 - 1.9e-15 55.9 11.9 0.054 14.1 0.1 6.9 4 1 3 7 7 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 AEO60186.1 - 2.4e-15 55.0 3.1 0.0083 15.8 0.0 7.5 6 2 2 8 8 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 AEO60186.1 - 3.3e-15 56.2 13.7 0.00018 22.0 0.0 4.9 3 1 0 4 4 4 4 Tetratricopeptide repeat TPR_9 PF13371.1 AEO60186.1 - 2.8e-11 43.1 1.7 0.00072 19.3 0.3 4.7 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 AEO60186.1 - 2.5e-08 33.8 10.6 0.13 12.8 0.1 7.5 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_17 PF13431.1 AEO60186.1 - 2.2e-07 30.5 2.6 0.0041 17.2 0.0 5.4 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 AEO60186.1 - 3.3e-07 30.5 14.4 0.028 14.7 0.0 6.0 4 1 1 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 AEO60186.1 - 5.3e-06 25.8 8.7 0.098 12.5 0.1 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 AEO60186.1 - 1.6e-05 24.7 14.4 0.00036 20.4 0.1 5.3 2 2 3 5 5 5 3 Tetratricopeptide repeat BTAD PF03704.12 AEO60186.1 - 0.00019 21.7 6.2 0.0036 17.6 0.0 4.0 2 1 2 4 4 4 1 Bacterial transcriptional activator domain SLS PF14611.1 AEO60186.1 - 0.0042 16.5 0.1 0.0081 15.6 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator BAR PF03114.13 AEO60186.1 - 0.056 12.9 0.4 0.056 12.9 0.3 2.5 2 1 0 2 2 2 0 BAR domain TPR_20 PF14561.1 AEO60186.1 - 0.35 11.0 0.0 0.35 11.0 0.0 3.9 3 2 2 5 5 5 0 Tetratricopeptide repeat HemY_N PF07219.8 AEO60186.1 - 3.3 7.3 7.0 1.6 8.2 2.2 2.6 2 0 0 2 2 2 0 HemY protein N-terminus Mito_carr PF00153.22 AEO60187.1 - 1.3e-71 236.3 6.9 5.6e-24 83.6 0.2 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein APG9 PF04109.11 AEO60188.1 - 3.2e-151 503.4 4.8 4.2e-151 503.0 3.3 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 COG6 PF06419.6 AEO60189.1 - 3.4e-220 732.3 8.2 3.8e-220 732.2 5.7 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 DASH_Dad3 PF08656.5 AEO60189.1 - 0.015 14.9 0.1 0.53 10.0 0.0 2.9 2 0 0 2 2 2 0 DASH complex subunit Dad3 Seryl_tRNA_N PF02403.17 AEO60189.1 - 0.18 11.8 8.6 0.025 14.6 1.6 2.8 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain COG2 PF06148.6 AEO60189.1 - 0.68 9.8 6.8 0.21 11.4 0.5 2.8 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 AAA PF00004.24 AEO60190.1 - 4.9e-38 130.3 0.0 9.4e-38 129.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 AEO60190.1 - 2.9e-08 33.4 0.0 7.4e-07 28.9 0.0 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.1 AEO60190.1 - 3.3e-05 24.0 1.3 0.00032 20.8 0.1 2.9 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 AEO60190.1 - 8e-05 21.7 0.0 0.00014 20.9 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 AEO60190.1 - 0.00067 19.3 0.0 0.0027 17.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 AEO60190.1 - 0.00074 18.3 0.0 0.0012 17.6 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 AEO60190.1 - 0.0023 17.3 0.0 0.0043 16.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.1 AEO60190.1 - 0.0024 17.8 4.0 0.0042 17.0 0.0 3.0 2 1 0 3 3 3 1 AAA ATPase domain Mg_chelatase PF01078.16 AEO60190.1 - 0.0039 16.3 0.1 0.0083 15.3 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 AEO60190.1 - 0.0041 16.0 0.0 0.0074 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.9 AEO60190.1 - 0.0044 16.9 0.0 0.0077 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 AEO60190.1 - 0.0058 16.3 0.1 0.028 14.1 0.0 2.2 2 0 0 2 2 1 1 Part of AAA domain AAA_11 PF13086.1 AEO60190.1 - 0.0074 15.8 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AEO60190.1 - 0.011 15.6 0.1 0.032 14.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 AEO60190.1 - 0.013 15.3 0.0 0.034 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 AEO60190.1 - 0.014 15.3 0.5 0.24 11.3 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.1 AEO60190.1 - 0.019 14.3 1.2 0.22 10.8 0.1 2.8 1 1 1 3 3 3 0 AAA domain AAA_17 PF13207.1 AEO60190.1 - 0.028 15.2 0.2 0.12 13.2 0.0 2.2 2 1 0 2 2 1 0 AAA domain MIT PF04212.13 AEO60190.1 - 0.037 13.8 0.1 0.1 12.4 0.1 1.7 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain AAA_24 PF13479.1 AEO60190.1 - 0.056 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 AEO60190.1 - 0.069 12.7 0.0 0.24 11.0 0.0 2.0 2 0 0 2 2 1 0 NACHT domain TPR_2 PF07719.12 AEO60190.1 - 0.077 12.9 0.0 0.23 11.4 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Guanylate_kin PF00625.16 AEO60190.1 - 0.11 11.9 0.0 0.26 10.6 0.0 1.7 1 0 0 1 1 1 0 Guanylate kinase Arch_ATPase PF01637.13 AEO60190.1 - 0.11 12.1 0.0 0.32 10.6 0.0 1.8 1 1 0 1 1 1 0 Archaeal ATPase PhoH PF02562.11 AEO60190.1 - 0.17 11.1 0.0 0.32 10.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.17 AEO60190.1 - 0.19 11.9 0.0 0.38 10.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase SRPRB PF09439.5 AEO60190.1 - 0.19 10.9 0.0 0.35 10.0 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Sigma54_activat PF00158.21 AEO60190.1 - 0.19 11.1 0.0 0.48 9.8 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Ribosomal_S17 PF00366.15 AEO60191.1 - 2.9e-09 36.8 0.4 4.6e-09 36.1 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 Cid2 PF09774.4 AEO60191.1 - 0.038 14.0 0.2 0.053 13.6 0.1 1.2 1 0 0 1 1 1 0 Caffeine-induced death protein 2 DUF4461 PF14688.1 AEO60191.1 - 0.18 11.1 0.2 0.24 10.7 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4461) DUF2013 PF09431.5 AEO60192.1 - 1.9e-51 173.4 1.9 1.9e-51 173.4 1.3 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF2013) TAT_ubiq PF07706.7 AEO60192.1 - 0.0014 18.4 0.3 0.0036 17.1 0.2 1.6 1 0 0 1 1 1 1 Aminotransferase ubiquitination site Pathogen_betaC1 PF09593.5 AEO60192.1 - 0.11 12.2 0.1 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Beta-satellite pathogenicity beta C1 protein LCAT PF02450.10 AEO60193.1 - 6e-98 328.3 0.0 8e-98 327.9 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Acetyltransf_1 PF00583.19 AEO60194.1 - 3.3e-18 65.4 0.0 5.6e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 AEO60194.1 - 2.5e-11 43.7 0.0 3.8e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 AEO60194.1 - 6.8e-10 38.9 0.0 1e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 AEO60194.1 - 9.9e-09 35.4 0.0 1.2e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 AEO60194.1 - 1.2e-08 34.6 0.0 2e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 AEO60194.1 - 3.3e-07 30.3 0.0 4e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 AEO60194.1 - 2.5e-06 27.3 0.0 4.3e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 AEO60194.1 - 0.00018 21.4 0.0 0.00028 20.8 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 AEO60194.1 - 0.00067 19.4 0.1 0.0013 18.5 0.1 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase GNAT_acetyltran PF12746.2 AEO60194.1 - 0.06 12.1 0.0 0.076 11.8 0.0 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase DUF1917 PF08939.5 AEO60195.1 - 2.2e-69 233.9 0.0 2.5e-69 233.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) WD40 PF00400.27 AEO60196.1 - 8.9e-06 25.3 1.0 0.99 9.4 0.0 4.9 5 1 0 5 5 5 2 WD domain, G-beta repeat Apc4_WD40 PF12894.2 AEO60196.1 - 0.13 11.8 0.0 1.7 8.1 0.0 2.7 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Xpo1 PF08389.7 AEO60197.1 - 1.9e-07 31.0 0.0 2.6e-05 24.1 0.0 3.0 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.14 AEO60197.1 - 0.00019 21.2 2.4 0.0014 18.4 0.0 3.6 4 0 0 4 4 4 1 Importin-beta N-terminal domain WYL PF13280.1 AEO60197.1 - 0.06 13.2 0.1 0.16 11.7 0.1 1.8 1 0 0 1 1 1 0 WYL domain DUF479 PF04336.7 AEO60197.1 - 0.21 11.6 2.6 2.5 8.2 1.9 2.8 1 1 1 2 2 2 0 Protein of unknown function, DUF479 TMF_TATA_bd PF12325.3 AEO60198.1 - 0.015 15.0 0.1 0.024 14.3 0.1 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding VBS PF08913.5 AEO60198.1 - 0.017 15.3 0.0 3.9 7.7 0.0 2.8 3 0 0 3 3 3 0 Vinculin Binding Site DUF1412 PF07203.6 AEO60198.1 - 0.018 14.9 0.0 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1412) Med4 PF10018.4 AEO60198.1 - 0.038 13.3 0.0 7.4 5.9 0.0 2.2 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 CD34_antigen PF06365.7 AEO60199.1 - 0.079 12.6 0.0 0.09 12.4 0.0 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family MadM PF03818.8 AEO60199.1 - 0.093 12.3 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 Malonate/sodium symporter MadM subunit Sec23_trunk PF04811.10 AEO60200.1 - 1.5e-71 240.6 0.0 2.6e-71 239.8 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 AEO60200.1 - 4.2e-24 83.9 0.1 1.3e-22 79.1 0.0 2.5 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 AEO60200.1 - 7.3e-18 63.8 5.3 1.3e-17 63.0 3.6 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 AEO60200.1 - 7.5e-18 64.8 0.1 1.5e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 AEO60200.1 - 1.5e-11 43.8 0.0 2.8e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat TEX12 PF15219.1 AEO60200.1 - 0.47 10.4 3.0 0.39 10.7 0.5 2.0 3 0 0 3 3 3 0 Testis-expressed 12 Pkinase PF00069.20 AEO60201.1 - 5.3e-75 251.9 0.0 7e-75 251.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO60201.1 - 6.7e-32 110.5 0.0 9e-32 110.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO60201.1 - 0.00039 19.4 0.0 0.00072 18.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 AEO60201.1 - 0.0021 17.1 0.1 0.0037 16.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AEO60201.1 - 0.01 15.5 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 AEO60201.1 - 0.039 12.7 0.0 0.06 12.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 TLD PF07534.11 AEO60202.1 - 1.7e-25 89.6 0.0 1.2e-14 54.4 0.0 2.3 2 0 0 2 2 2 2 TLD HEM4 PF02602.10 AEO60203.1 - 4.7e-39 133.9 0.0 6e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Evr1_Alr PF04777.8 AEO60204.1 - 9.6e-30 102.3 0.7 9.6e-30 102.3 0.5 1.7 2 0 0 2 2 2 1 Erv1 / Alr family TPP_enzyme_N PF02776.13 AEO60205.1 - 2.8e-34 118.0 0.0 5.5e-34 117.1 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 AEO60205.1 - 3.1e-32 111.1 0.0 6.6e-32 110.1 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 AEO60205.1 - 1.7e-15 56.9 0.5 2.2e-14 53.2 0.0 2.7 2 1 1 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain OCC1 PF15506.1 AEO60205.1 - 0.15 11.9 2.4 3.6 7.5 0.1 3.0 3 0 0 3 3 3 0 OCC1 family THUMP PF02926.12 AEO60206.1 - 8.8e-12 45.1 0.0 9.2e-08 32.0 0.0 2.3 2 0 0 2 2 2 2 THUMP domain Pex14_N PF04695.8 AEO60207.1 - 0.0056 16.7 5.2 0.01 15.8 3.6 1.4 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.9 AEO60207.1 - 0.057 13.1 7.7 0.082 12.6 5.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Ycf1 PF05758.7 AEO60207.1 - 0.064 10.9 3.6 0.083 10.6 2.5 1.0 1 0 0 1 1 1 0 Ycf1 Zip PF02535.17 AEO60207.1 - 0.16 10.9 9.5 0.24 10.3 6.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Macoilin PF09726.4 AEO60207.1 - 0.33 9.1 5.5 0.44 8.7 3.8 1.1 1 0 0 1 1 1 0 Transmembrane protein Med15 PF09606.5 AEO60207.1 - 0.4 8.8 26.0 0.65 8.1 18.0 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MMR1 PF08505.5 AEO60207.1 - 0.69 9.8 8.5 1.2 9.1 5.9 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF3043 PF11241.3 AEO60207.1 - 4.1 6.9 8.8 7.3 6.1 6.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Borrelia_P83 PF05262.6 AEO60207.1 - 4.8 5.3 8.5 6.4 4.9 5.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Neur_chan_memb PF02932.11 AEO60207.1 - 8.4 6.1 7.4 13 5.5 5.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.7 AEO60207.1 - 9.3 6.0 13.6 16 5.2 9.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SGT1 PF07093.6 AEO60208.1 - 4.3e-151 504.2 26.7 1.4e-149 499.2 18.5 2.1 1 1 0 1 1 1 1 SGT1 protein DUF3439 PF11921.3 AEO60208.1 - 0.16 11.6 0.6 0.3 10.8 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) ASFV_J13L PF05568.6 AEO60208.1 - 0.36 10.3 1.7 10 5.5 0.1 2.4 2 0 0 2 2 2 0 African swine fever virus J13L protein SMC_N PF02463.14 AEO60209.1 - 2.1e-26 92.5 0.0 4.2e-26 91.5 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 AEO60209.1 - 1.4e-09 38.5 68.1 2.7e-09 37.6 25.4 5.7 2 2 0 2 2 2 1 AAA domain AAA_21 PF13304.1 AEO60209.1 - 1.8e-05 24.8 5.4 0.00041 20.4 0.3 3.0 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 AEO60209.1 - 0.00018 21.3 0.0 0.00052 19.8 0.0 1.8 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 AEO60209.1 - 0.00078 18.9 0.0 0.0018 17.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 AEO60209.1 - 0.00083 18.5 0.0 0.00083 18.5 0.0 2.4 3 0 0 3 3 3 1 AAA ATPase domain Reo_sigmaC PF04582.7 AEO60209.1 - 0.013 14.7 7.4 0.24 10.5 0.1 3.9 2 2 2 4 4 4 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 AEO60209.1 - 4.4 5.6 71.0 0.3 9.4 0.0 5.8 3 2 4 7 7 7 0 AAA domain ABC_tran PF00005.22 AEO60209.1 - 9.8 6.4 22.7 27 5.0 1.4 5.0 2 2 0 2 2 2 0 ABC transporter COQ9 PF08511.6 AEO60210.1 - 4.3e-28 96.6 0.0 6.8e-28 96.0 0.0 1.3 1 0 0 1 1 1 1 COQ9 RRM_1 PF00076.17 AEO60211.1 - 2e-53 177.9 0.0 2.6e-17 62.2 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO60211.1 - 2.5e-42 142.7 0.0 3.2e-14 52.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO60211.1 - 4e-25 87.4 0.0 5.7e-07 29.2 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 AEO60211.1 - 7e-07 28.9 0.1 0.16 11.7 0.0 3.9 3 2 0 3 3 3 3 Limkain b1 RRM_3 PF08777.6 AEO60211.1 - 9.1e-07 28.6 0.0 0.32 10.8 0.0 3.3 3 0 0 3 3 3 2 RNA binding motif ATP-grasp_2 PF08442.5 AEO60211.1 - 9.6e-05 21.8 0.0 0.009 15.4 0.0 2.8 3 0 0 3 3 3 1 ATP-grasp domain PknH_C PF14032.1 AEO60211.1 - 0.1 12.1 0.0 78 2.7 0.0 3.1 3 0 0 3 3 3 0 PknH-like extracellular domain SRP14 PF02290.10 AEO60212.1 - 2.2e-25 88.3 0.0 3e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle 14kD protein Vps36_ESCRT-II PF11605.3 AEO60212.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.5 1 1 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 MIF4G PF02854.14 AEO60213.1 - 3.9e-23 81.9 0.4 1.9e-21 76.4 0.1 2.2 2 0 0 2 2 2 2 MIF4G domain MA3 PF02847.12 AEO60213.1 - 1.3e-15 57.0 0.1 1.4e-14 53.7 0.0 2.8 3 1 0 3 3 3 1 MA3 domain Pyr_redox_dim PF02852.17 AEO60214.1 - 1.6e-39 134.3 0.2 5.8e-39 132.5 0.0 2.1 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 AEO60214.1 - 8.1e-38 130.3 15.3 4.9e-37 127.7 10.1 3.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AEO60214.1 - 1.8e-27 95.5 9.3 4e-23 81.6 0.4 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AEO60214.1 - 2.3e-12 46.7 1.9 2.3e-06 27.5 0.2 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 AEO60214.1 - 3.3e-10 39.6 4.1 1.3e-09 37.7 0.1 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 AEO60214.1 - 5.5e-10 39.6 0.5 8.9e-06 25.8 0.2 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 AEO60214.1 - 1.3e-08 34.1 16.9 8.2e-05 21.6 1.3 4.2 2 2 0 4 4 4 3 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 AEO60214.1 - 2.5e-08 33.2 9.0 5.4e-07 28.8 1.7 3.3 3 0 0 3 3 3 1 FAD binding domain GIDA PF01134.17 AEO60214.1 - 2.5e-08 33.2 11.1 4.2e-07 29.1 2.4 3.1 2 2 1 3 3 3 2 Glucose inhibited division protein A HI0933_like PF03486.9 AEO60214.1 - 6.2e-08 31.5 11.8 7.5e-05 21.3 1.2 4.2 4 0 0 4 4 4 3 HI0933-like protein K_oxygenase PF13434.1 AEO60214.1 - 9.2e-06 24.8 0.1 0.082 11.8 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.16 AEO60214.1 - 9.7e-06 25.2 1.7 0.048 13.2 0.1 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 AEO60214.1 - 2.1e-05 23.7 1.6 0.00021 20.4 0.0 2.3 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 AEO60214.1 - 7.5e-05 21.9 7.5 0.1 11.6 1.1 3.3 3 0 0 3 3 3 2 FAD binding domain 3HCDH_N PF02737.13 AEO60214.1 - 0.0077 15.8 6.0 0.0098 15.5 0.1 2.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 AEO60214.1 - 0.0093 16.2 1.9 3.7 7.8 0.0 3.0 2 1 0 2 2 2 1 Putative NAD(P)-binding Lycopene_cycl PF05834.7 AEO60214.1 - 0.014 14.2 4.1 0.041 12.8 0.4 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein 2-Hacid_dh_C PF02826.14 AEO60214.1 - 0.025 13.7 1.0 3.6 6.6 0.1 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 AEO60214.1 - 0.027 13.0 5.1 0.051 12.1 0.5 2.2 2 0 0 2 2 2 0 Tryptophan halogenase UDPG_MGDP_dh_N PF03721.9 AEO60214.1 - 0.028 13.8 3.4 0.28 10.5 0.1 2.4 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FMO-like PF00743.14 AEO60214.1 - 0.069 11.3 2.2 0.78 7.8 0.3 2.1 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like Amino_oxidase PF01593.19 AEO60214.1 - 0.44 9.5 2.0 1 8.3 0.1 2.2 2 1 1 3 3 3 0 Flavin containing amine oxidoreductase F420_oxidored PF03807.12 AEO60214.1 - 3.8 7.9 6.6 2.2 8.7 0.1 3.3 4 0 0 4 4 3 0 NADP oxidoreductase coenzyme F420-dependent FA_desaturase PF00487.19 AEO60215.1 - 1.1e-37 129.8 33.2 1.5e-37 129.4 23.0 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 AEO60215.1 - 9e-13 47.8 0.0 1.6e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAM60A PF15396.1 AEO60215.1 - 0.28 10.8 1.2 0.66 9.6 0.9 1.5 1 1 0 1 1 1 0 Protein Family FAM60A SLD3 PF08639.5 AEO60215.1 - 0.28 9.7 8.5 0.5 8.9 5.6 1.5 2 0 0 2 2 2 0 DNA replication regulator SLD3 SR-25 PF10500.4 AEO60216.1 - 0.19 11.1 10.1 0.2 11.1 7.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 AEO60216.1 - 2.6 8.1 8.9 2.9 7.9 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Vac14_Fig4_bd PF11916.3 AEO60217.1 - 9.8e-84 279.0 8.1 9.8e-84 279.0 5.6 1.7 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 AEO60217.1 - 8.8e-46 154.2 0.0 2.4e-42 143.2 0.0 4.1 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 AEO60217.1 - 2.6e-09 36.3 3.2 0.00013 21.7 0.0 6.2 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.1 AEO60217.1 - 2.4e-07 31.0 6.5 0.00046 20.5 0.1 5.1 4 0 0 4 4 4 2 HEAT-like repeat HEAT_2 PF13646.1 AEO60217.1 - 3.8e-06 27.0 2.0 0.034 14.4 0.0 4.8 5 0 0 5 5 5 2 HEAT repeats Cnd1 PF12717.2 AEO60217.1 - 0.0005 19.9 1.1 1.4 8.7 0.2 3.0 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 AEO60217.1 - 0.0007 19.3 0.0 0.81 9.6 0.0 4.4 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Microtub_assoc PF07989.6 AEO60219.1 - 3.9e-29 100.2 5.3 3.9e-29 100.2 3.6 5.5 4 2 1 5 5 4 1 Microtubule associated ATG16 PF08614.6 AEO60219.1 - 0.00012 21.9 60.0 0.00022 21.0 13.8 4.3 1 1 3 4 4 4 1 Autophagy protein 16 (ATG16) MscS_porin PF12795.2 AEO60219.1 - 0.00038 19.8 46.2 0.08 12.2 16.3 2.4 1 1 1 2 2 2 2 Mechanosensitive ion channel porin domain IncA PF04156.9 AEO60219.1 - 0.00038 20.1 68.9 0.76 9.3 26.2 3.5 1 1 1 2 2 2 2 IncA protein Reo_sigmaC PF04582.7 AEO60219.1 - 0.00058 19.1 7.1 0.017 14.2 0.8 2.6 1 1 2 3 3 3 2 Reovirus sigma C capsid protein NPV_P10 PF05531.7 AEO60219.1 - 0.0015 18.7 21.8 0.39 11.0 0.4 5.2 2 1 2 4 4 4 2 Nucleopolyhedrovirus P10 protein AAA_13 PF13166.1 AEO60219.1 - 0.0018 16.8 40.5 0.005 15.3 16.4 2.2 1 1 1 2 2 2 2 AAA domain Cast PF10174.4 AEO60219.1 - 0.0031 15.6 69.0 0.0085 14.2 43.2 2.3 1 1 1 2 2 2 2 RIM-binding protein of the cytomatrix active zone TPR_MLP1_2 PF07926.7 AEO60219.1 - 0.015 15.0 55.3 0.03 14.0 11.6 3.4 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.4 AEO60219.1 - 0.019 14.8 69.2 0.87 9.4 7.1 4.4 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_tail_1 PF01576.14 AEO60219.1 - 0.044 11.5 74.4 0.22 9.2 51.6 2.4 1 1 0 1 1 1 0 Myosin tail ERM PF00769.14 AEO60219.1 - 0.058 12.9 73.6 0.093 12.2 24.0 2.7 2 1 2 4 4 3 0 Ezrin/radixin/moesin family Tropomyosin_1 PF12718.2 AEO60219.1 - 0.096 12.5 74.9 1.4 8.7 10.5 4.8 1 1 3 4 4 4 0 Tropomyosin like Laminin_II PF06009.7 AEO60219.1 - 0.15 11.8 28.5 0.076 12.7 1.8 4.5 1 1 3 4 4 4 0 Laminin Domain II Fib_alpha PF08702.5 AEO60219.1 - 0.15 12.1 36.4 0.18 11.9 6.4 3.4 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family MAD PF05557.8 AEO60219.1 - 0.19 9.7 63.1 3 5.8 43.7 2.2 1 1 0 1 1 1 0 Mitotic checkpoint protein AATF-Che1 PF13339.1 AEO60219.1 - 0.36 11.0 35.5 1.8 8.7 5.4 3.6 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor WEMBL PF05701.6 AEO60219.1 - 0.41 9.0 56.6 1.8 6.9 39.1 1.9 1 1 0 1 1 1 0 Weak chloroplast movement under blue light Mnd1 PF03962.10 AEO60219.1 - 0.42 10.2 57.7 0.073 12.7 12.9 3.5 1 1 3 4 4 4 0 Mnd1 family Spc7 PF08317.6 AEO60219.1 - 0.53 8.8 55.1 0.028 13.1 11.3 3.3 1 1 2 3 3 3 0 Spc7 kinetochore protein FliJ PF02050.11 AEO60219.1 - 0.92 9.5 54.2 0.63 10.0 9.1 4.5 1 1 4 5 5 5 0 Flagellar FliJ protein Rootletin PF15035.1 AEO60219.1 - 1.9 8.4 58.8 0.42 10.5 14.6 3.9 1 1 3 4 4 4 0 Ciliary rootlet component, centrosome cohesion DUF2408 PF10303.4 AEO60219.1 - 2 8.5 32.5 10 6.2 8.6 3.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) DUF342 PF03961.8 AEO60219.1 - 2.2 6.6 40.7 0.28 9.5 5.3 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF342) DUF812 PF05667.6 AEO60219.1 - 2.2 6.6 49.3 0.35 9.3 13.5 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Baculo_PEP_C PF04513.7 AEO60219.1 - 2.3 8.0 13.7 9.8 6.0 0.3 3.7 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus COG2 PF06148.6 AEO60219.1 - 2.5 7.9 39.5 3.1 7.6 3.9 4.8 1 1 3 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Prefoldin_2 PF01920.15 AEO60219.1 - 3.5 7.4 63.6 0.21 11.3 14.0 6.0 2 2 4 6 6 6 0 Prefoldin subunit Tweety PF04906.8 AEO60219.1 - 5.5 5.3 14.2 0.14 10.5 1.4 2.6 1 1 2 3 3 3 0 Tweety DUF972 PF06156.8 AEO60219.1 - 5.5 7.3 50.6 0.47 10.8 2.1 5.5 1 1 4 5 5 5 0 Protein of unknown function (DUF972) DUF948 PF06103.6 AEO60219.1 - 6.6 6.6 15.6 2.3 8.1 0.2 4.2 1 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) EzrA PF06160.7 AEO60219.1 - 6.7 4.7 47.1 0.17 9.9 8.5 3.8 1 1 1 3 3 3 0 Septation ring formation regulator, EzrA Glutaredoxin2_C PF04399.8 AEO60219.1 - 8.2 6.0 15.6 4.2 6.9 0.2 3.9 2 2 1 3 3 3 0 Glutaredoxin 2, C terminal domain Phage_GP20 PF06810.6 AEO60219.1 - 9.3 5.6 50.2 0.4 10.0 9.3 4.4 1 1 3 4 4 4 0 Phage minor structural protein GP20 TMF_TATA_bd PF12325.3 AEO60219.1 - 9.8 5.9 60.3 1 9.0 5.2 4.3 1 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding Toxin_44 PF15523.1 AEO60220.1 - 0.017 14.9 0.3 0.025 14.4 0.2 1.2 1 0 0 1 1 1 0 Putative toxin 44 DUF863 PF05904.6 AEO60220.1 - 0.26 9.5 1.2 0.31 9.2 0.8 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF863) Peptidase_C14 PF00656.17 AEO60221.1 - 2.1e-73 247.0 0.0 2.5e-73 246.8 0.0 1.1 1 0 0 1 1 1 1 Caspase domain RAB3GAP2_N PF14655.1 AEO60223.1 - 0.072 12.0 0.6 0.12 11.3 0.4 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Syndecan PF01034.15 AEO60223.1 - 0.19 11.4 0.1 0.38 10.4 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain Herpes_gE PF02480.11 AEO60223.1 - 0.24 9.6 2.3 0.13 10.5 0.1 1.6 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E SKG6 PF08693.5 AEO60223.1 - 9.6 5.6 9.4 0.18 11.1 0.6 2.4 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Whi5 PF08528.6 AEO60224.1 - 3.7e-09 35.9 0.5 6.7e-09 35.1 0.3 1.5 1 0 0 1 1 1 1 Whi5 like Metallopep PF12044.3 AEO60225.1 - 2.3e-169 563.3 0.0 2.9e-169 562.9 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.12 AEO60225.1 - 6.4e-07 29.3 0.0 1.1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Jacalin-like lectin domain Peptidase_M10 PF00413.19 AEO60225.1 - 0.062 13.0 0.0 0.17 11.6 0.0 1.7 1 1 0 1 1 1 0 Matrixin Reprolysin_2 PF13574.1 AEO60225.1 - 0.083 12.9 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 AEO60225.1 - 0.099 13.1 0.1 0.21 12.0 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 AEO60225.1 - 0.16 10.8 0.4 0.35 9.6 0.3 1.5 1 0 0 1 1 1 0 Peptidase M66 Astacin PF01400.19 AEO60225.1 - 0.21 10.9 0.0 0.35 10.2 0.0 1.2 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) DUF2410 PF10307.4 AEO60226.1 - 1.7e-82 275.6 0.0 2.3e-82 275.1 0.0 1.2 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) zf-C2H2_jaz PF12171.3 AEO60227.1 - 1.8e-10 40.6 0.5 3.6e-10 39.6 0.4 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 AEO60227.1 - 0.012 15.4 0.3 0.021 14.7 0.2 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 AEO60227.1 - 0.053 13.6 0.4 0.33 11.0 0.1 1.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 AEO60227.1 - 0.094 12.9 0.8 0.15 12.3 0.2 1.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 AEO60227.1 - 0.11 12.9 0.2 0.34 11.3 0.1 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger Aconitase PF00330.15 AEO60228.1 - 3.1e-175 583.1 0.0 7.5e-175 581.8 0.0 1.6 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 AEO60228.1 - 1.4e-45 154.5 0.0 2.5e-45 153.8 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Rhomboid PF01694.17 AEO60229.1 - 2.7e-14 53.4 9.0 3.9e-14 52.9 6.3 1.3 1 0 0 1 1 1 1 Rhomboid family Gaa1 PF04114.9 AEO60230.1 - 1.1e-97 327.8 2.1 2.3e-97 326.8 1.4 1.5 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component PCI PF01399.22 AEO60231.1 - 4.9e-10 39.6 0.0 1.4e-09 38.1 0.0 1.8 1 0 0 1 1 1 1 PCI domain NmrA PF05368.8 AEO60232.1 - 1.8e-17 63.3 0.0 2.2e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 AEO60232.1 - 4.6e-17 62.6 0.0 7.1e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 AEO60232.1 - 2.5e-15 56.5 0.0 6.3e-15 55.2 0.0 1.8 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 AEO60232.1 - 7.1e-11 41.3 0.0 1.3e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 AEO60232.1 - 8.3e-08 31.4 0.0 5e-06 25.6 0.0 2.4 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 AEO60232.1 - 0.00015 20.8 0.5 0.0053 15.7 0.3 2.6 1 1 1 2 2 2 1 Male sterility protein adh_short PF00106.20 AEO60232.1 - 0.00016 21.6 0.2 0.00056 19.8 0.0 2.1 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 AEO60232.1 - 0.0043 16.7 0.1 0.13 11.9 0.0 2.9 3 1 0 3 3 3 1 KR domain Saccharop_dh PF03435.13 AEO60232.1 - 0.0044 16.0 0.0 0.0064 15.5 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 AEO60232.1 - 0.0072 15.2 0.0 0.012 14.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_synthase PF02540.12 AEO60232.1 - 0.02 13.8 0.0 0.031 13.1 0.0 1.3 1 0 0 1 1 1 0 NAD synthase NAD_binding_2 PF03446.10 AEO60232.1 - 0.037 13.8 0.1 0.23 11.2 0.0 2.2 2 1 1 3 3 3 0 NAD binding domain of 6-phosphogluconate dehydrogenase DDE_Tnp_1_3 PF13612.1 AEO60232.1 - 0.12 12.1 0.0 0.44 10.2 0.0 1.9 2 0 0 2 2 2 0 Transposase DDE domain N6-adenineMlase PF10237.4 AEO60233.1 - 1.6e-57 193.6 0.0 2e-57 193.3 0.0 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase UCH PF00443.24 AEO60234.1 - 1.9e-56 191.1 5.3 3.5e-56 190.2 3.7 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AEO60234.1 - 2.8e-34 118.8 1.7 5.1e-34 118.0 1.2 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 AEO60234.1 - 0.00038 20.4 0.1 0.00038 20.4 0.1 2.9 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein Lactamase_B PF00753.22 AEO60235.1 - 2.7e-23 82.6 4.5 2.7e-23 82.6 3.1 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 AEO60235.1 - 6.6e-05 22.5 0.1 0.00018 21.0 0.1 1.8 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 AEO60235.1 - 0.0012 18.5 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Ytp1 PF10355.4 AEO60236.1 - 3.7e-113 377.2 3.4 5e-113 376.8 2.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 AEO60236.1 - 1.2e-20 73.0 1.1 1.2e-20 73.0 0.8 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) DUF3481 PF11980.3 AEO60236.1 - 0.41 10.5 1.8 1.4 8.7 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3481) Transglut_core2 PF13369.1 AEO60237.1 - 2.7e-15 56.1 0.0 5.1e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.2 AEO60237.1 - 6.6e-06 25.7 2.8 1.6e-05 24.5 1.9 1.7 1 0 0 1 1 1 1 F-box-like YccV-like PF08755.6 AEO60237.1 - 7.2e-06 25.8 0.1 2e-05 24.4 0.0 1.8 2 0 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like F-box PF00646.28 AEO60237.1 - 0.00011 21.7 0.8 0.00029 20.3 0.5 1.8 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.1 AEO60237.1 - 0.028 14.1 0.1 0.073 12.8 0.1 1.7 1 0 0 1 1 1 0 F-box-like domain tRNA-synt_2b PF00587.20 AEO60238.1 - 9.2e-45 152.3 0.3 1.4e-44 151.7 0.2 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_SAD PF07973.9 AEO60238.1 - 2.8e-13 49.5 0.0 6.8e-13 48.2 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 AEO60238.1 - 1.5e-10 40.7 0.0 3e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 TGS domain Pro-NT_NN PF07421.6 AEO60238.1 - 0.058 12.8 0.1 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Neurotensin/neuromedin N precursor tRNA-synt_His PF13393.1 AEO60238.1 - 0.099 11.6 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Histidyl-tRNA synthetase CDP-OH_P_transf PF01066.16 AEO60239.1 - 4.7e-14 52.5 2.1 9.1e-14 51.5 1.5 1.5 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Peptidase_C12 PF01088.16 AEO60240.1 - 5.1e-53 179.4 0.0 9.8e-52 175.2 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 SpoVR PF04293.8 AEO60240.1 - 0.16 10.3 0.1 0.24 9.7 0.1 1.2 1 0 0 1 1 1 0 SpoVR like protein I-set PF07679.11 AEO60241.1 - 0.0028 17.4 0.0 53 3.7 0.0 4.7 4 0 0 4 4 4 2 Immunoglobulin I-set domain DUF1918 PF08940.6 AEO60241.1 - 0.0036 16.5 0.1 17 4.8 0.0 4.6 4 0 0 4 4 4 2 Domain of unknown function (DUF1918) HSF_DNA-bind PF00447.12 AEO60242.1 - 4.8e-34 116.6 0.2 8.7e-34 115.8 0.1 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding CENP-H PF05837.7 AEO60242.1 - 0.0041 17.2 6.9 0.0065 16.6 4.8 1.3 1 0 0 1 1 1 1 Centromere protein H (CENP-H) IncA PF04156.9 AEO60242.1 - 0.02 14.5 3.1 0.029 13.9 2.1 1.2 1 0 0 1 1 1 0 IncA protein DUF972 PF06156.8 AEO60242.1 - 0.082 13.2 3.0 0.17 12.2 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) GBP_C PF02841.9 AEO60242.1 - 0.14 11.3 3.9 0.2 10.8 2.7 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain RR_TM4-6 PF06459.7 AEO60243.1 - 0.098 12.5 2.2 0.12 12.2 1.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Med15 PF09606.5 AEO60243.1 - 0.17 10.0 52.7 0.21 9.7 36.5 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal AUX_IAA PF02309.11 AEO60243.1 - 0.21 11.3 1.7 0.27 10.9 1.2 1.2 1 0 0 1 1 1 0 AUX/IAA family Phage_GPD PF05954.6 AEO60243.1 - 0.28 10.3 14.1 0.4 9.8 9.8 1.1 1 0 0 1 1 1 0 Phage late control gene D protein (GPD) Spore_coat_CotO PF14153.1 AEO60243.1 - 0.37 10.1 5.0 0.48 9.8 3.5 1.1 1 0 0 1 1 1 0 Spore coat protein CotO MMR1 PF08505.5 AEO60243.1 - 0.85 9.6 10.2 2 8.3 7.0 1.6 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein FixO PF02433.10 AEO60243.1 - 1.2 8.4 4.4 1.6 8.0 3.1 1.1 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO DUF4407 PF14362.1 AEO60243.1 - 1.6 7.6 17.1 2.1 7.1 11.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TFIIA PF03153.8 AEO60243.1 - 1.6 8.5 28.0 2.1 8.1 19.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 AEO60243.1 - 2.4 6.3 32.5 3 5.9 22.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 W2 PF02020.13 AEO60244.1 - 8.8e-17 60.8 1.3 8.8e-17 60.8 0.9 2.8 2 1 1 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 AEO60244.1 - 1.6e-06 27.3 15.9 0.0032 16.8 1.5 4.2 2 1 3 5 5 5 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 AEO60244.1 - 3e-05 23.4 0.0 5.2e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.1 AEO60244.1 - 0.82 9.2 12.2 0.22 11.0 1.0 3.2 1 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase Nucleoplasmin PF03066.10 AEO60244.1 - 6.6 6.2 15.9 12 5.4 8.0 2.4 2 0 0 2 2 2 0 Nucleoplasmin Rsa3 PF14615.1 AEO60245.1 - 5.3e-22 76.8 0.9 6.3e-22 76.5 0.6 1.1 1 0 0 1 1 1 1 Ribosome-assembly protein 3 RTA1 PF04479.8 AEO60246.1 - 2.6e-08 33.6 8.0 3.4e-06 26.7 2.0 3.0 2 1 0 2 2 2 2 RTA1 like protein OstA_C PF04453.9 AEO60246.1 - 0.12 11.4 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Organic solvent tolerance protein PAS_9 PF13426.1 AEO60248.1 - 3.4e-31 107.6 0.0 2.1e-18 66.5 0.0 3.5 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.6 AEO60248.1 - 1.1e-21 76.6 0.0 8.6e-14 51.4 0.0 3.5 3 0 0 3 3 3 3 PAS fold PAS PF00989.19 AEO60248.1 - 3.9e-18 65.2 0.0 1.6e-06 27.8 0.0 3.5 3 0 0 3 3 3 3 PAS fold GATA PF00320.22 AEO60248.1 - 1e-14 53.5 8.0 2.1e-14 52.5 5.6 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS_4 PF08448.5 AEO60248.1 - 6.4e-09 35.8 0.0 0.032 14.2 0.0 3.6 3 0 0 3 3 3 2 PAS fold PAS_11 PF14598.1 AEO60248.1 - 7.6e-06 25.8 0.0 0.00099 19.0 0.0 2.6 2 0 0 2 2 2 1 PAS domain PAS_8 PF13188.1 AEO60248.1 - 0.059 13.2 0.0 3.1 7.8 0.0 2.8 3 0 0 3 3 3 0 PAS domain Cytochrom_c3_2 PF14537.1 AEO60248.1 - 0.18 12.1 0.2 0.41 11.0 0.2 1.5 1 0 0 1 1 1 0 Cytochrome c3 HEAT_2 PF13646.1 AEO60249.1 - 6.3e-23 80.8 20.2 2.8e-09 37.1 0.2 8.3 3 3 8 11 11 11 9 HEAT repeats HEAT PF02985.17 AEO60249.1 - 9e-22 75.1 17.8 0.0013 18.6 0.0 11.3 12 0 0 12 12 12 6 HEAT repeat HEAT_EZ PF13513.1 AEO60249.1 - 8.4e-15 54.7 28.4 1.9e-08 34.5 0.1 10.2 9 2 4 13 13 11 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 AEO60249.1 - 2.6e-13 50.1 0.1 0.012 16.0 0.0 7.3 4 2 4 8 8 7 2 Vacuolar 14 Fab1-binding region MMS19_C PF12460.3 AEO60249.1 - 8.8e-08 31.2 0.2 9.4e-05 21.3 0.0 4.1 4 1 1 5 5 5 1 RNAPII transcription regulator C-terminal CLASP_N PF12348.3 AEO60249.1 - 4.2e-07 29.5 0.5 0.018 14.3 0.0 5.8 5 2 2 7 7 7 1 CLASP N terminal RIX1 PF08167.7 AEO60249.1 - 1.3e-06 28.1 0.1 0.097 12.3 0.0 5.2 5 1 3 8 8 8 3 rRNA processing/ribosome biogenesis Cnd1 PF12717.2 AEO60249.1 - 8e-06 25.8 1.1 0.11 12.3 0.1 5.2 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Xpo1 PF08389.7 AEO60249.1 - 2.9e-05 24.0 0.2 0.00069 19.5 0.0 3.4 2 1 1 3 3 3 1 Exportin 1-like protein DUF4042 PF13251.1 AEO60249.1 - 0.00048 19.6 0.5 2.4 7.6 0.0 4.7 4 1 0 4 4 4 1 Domain of unknown function (DUF4042) Proteasom_PSMB PF10508.4 AEO60249.1 - 0.00068 18.0 0.1 0.008 14.4 0.0 2.6 3 0 0 3 3 3 1 Proteasome non-ATPase 26S subunit TAN PF11640.3 AEO60249.1 - 0.004 16.8 0.0 0.42 10.3 0.0 3.4 3 0 0 3 3 3 1 Telomere-length maintenance and DNA damage repair CAS_CSE1 PF03378.10 AEO60249.1 - 0.01 14.1 2.2 3.2 5.9 0.0 4.3 6 0 0 6 6 6 0 CAS/CSE protein, C-terminus Dopey_N PF04118.9 AEO60249.1 - 0.016 14.0 1.2 0.29 9.8 0.0 3.2 3 1 2 5 5 5 0 Dopey, N-terminal IBN_N PF03810.14 AEO60249.1 - 0.03 14.2 0.2 0.74 9.7 0.0 3.6 3 1 0 3 3 3 0 Importin-beta N-terminal domain Cohesin_HEAT PF12765.2 AEO60249.1 - 0.049 13.5 0.1 4.9 7.2 0.0 3.3 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion DUF3385 PF11865.3 AEO60249.1 - 0.18 11.7 3.1 84 3.0 0.0 5.2 4 1 0 5 5 5 0 Domain of unknown function (DUF3385) Arm PF00514.18 AEO60249.1 - 0.28 11.0 20.3 0.82 9.5 0.0 6.5 9 0 0 9 9 8 0 Armadillo/beta-catenin-like repeat CBS PF00571.23 AEO60250.1 - 5.2e-17 61.3 1.9 0.00063 19.4 0.1 5.2 5 0 0 5 5 5 4 CBS domain Inp1 PF12634.2 AEO60251.1 - 1.6e-36 125.1 0.0 4.1e-36 123.8 0.0 1.7 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 EI24 PF07264.6 AEO60252.1 - 3.5e-08 33.1 14.2 9.4e-07 28.4 9.9 2.6 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Reticulon PF02453.12 AEO60252.1 - 0.052 13.1 0.6 0.18 11.3 0.2 2.1 2 1 0 2 2 2 0 Reticulon FmdA_AmdA PF03069.10 AEO60253.1 - 1.6e-33 115.9 0.0 1.9e-33 115.6 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family OTU PF02338.14 AEO60255.1 - 3.6e-14 53.3 0.0 5.5e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_M29 PF02073.10 AEO60255.1 - 0.045 12.5 0.0 0.061 12.0 0.0 1.1 1 0 0 1 1 1 0 Thermophilic metalloprotease (M29) Bromodomain PF00439.20 AEO60256.1 - 2.5e-42 142.6 0.3 3.2e-20 71.8 0.0 2.6 2 0 0 2 2 2 2 Bromodomain BAH PF01426.13 AEO60256.1 - 1.4e-16 60.3 0.2 3.2e-16 59.1 0.2 1.7 1 0 0 1 1 1 1 BAH domain Brix PF04427.13 AEO60256.1 - 0.045 13.4 0.0 0.23 11.1 0.0 2.0 2 0 0 2 2 2 0 Brix domain AT_hook PF02178.14 AEO60256.1 - 9.7 6.2 15.1 0.32 10.7 1.2 3.2 2 0 0 2 2 2 0 AT hook motif DUF3456 PF11938.3 AEO60257.1 - 0.05 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 TLR4 regulator and MIR-interacting MSAP Mito_carr PF00153.22 AEO60258.1 - 2e-44 149.2 3.9 3.9e-20 71.3 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein SNF2_N PF00176.18 AEO60259.1 - 3.5e-67 226.3 0.0 4.7e-67 225.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 AEO60259.1 - 3.4e-62 209.7 2.6 1.4e-61 207.7 1.6 2.1 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.26 AEO60259.1 - 4.1e-13 48.9 0.0 1.8e-12 46.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 AEO60259.1 - 2e-05 23.5 0.0 5.1e-05 22.2 0.0 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 AEO60259.1 - 0.0011 18.8 0.0 0.0023 17.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 AEO60259.1 - 0.02 15.0 0.1 0.18 11.9 0.0 2.6 3 1 0 3 3 3 0 AAA domain Citrate_ly_lig PF08218.6 AEO60259.1 - 0.22 10.9 0.0 0.44 9.9 0.0 1.4 1 0 0 1 1 1 0 Citrate lyase ligase C-terminal domain UDP-g_GGTase PF06427.6 AEO60260.1 - 1e-60 204.6 0.0 2.7e-59 200.0 0.0 2.4 2 0 0 2 2 2 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 AEO60260.1 - 0.0012 18.2 1.5 0.0043 16.4 1.1 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 8 Coatomer_WDAD PF04053.9 AEO60261.1 - 6.6e-149 496.4 0.0 1e-148 495.8 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 AEO60261.1 - 6.9e-84 281.8 0.0 1e-83 281.2 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 AEO60261.1 - 1.2e-51 170.7 11.7 1.6e-09 37.2 0.0 8.5 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 AEO60261.1 - 0.032 12.3 8.3 0.29 9.2 0.0 3.7 2 1 2 4 4 4 0 Nucleoporin Nup120/160 Clathrin PF00637.15 AEO60261.1 - 0.076 12.6 0.2 0.38 10.3 0.0 2.1 2 0 0 2 2 2 0 Region in Clathrin and VPS Sel1 PF08238.7 AEO60262.1 - 3.1e-20 72.1 26.3 4.9e-08 33.3 0.1 7.3 7 0 0 7 7 7 5 Sel1 repeat TPR_1 PF00515.23 AEO60262.1 - 0.024 14.2 1.1 0.11 12.1 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 AEO60262.1 - 0.15 11.7 4.3 0.26 10.9 0.0 2.9 3 0 0 3 3 3 0 TPR repeat TPR_2 PF07719.12 AEO60262.1 - 3.1 7.9 0.0 3.1 7.9 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 AEO60262.1 - 6.2 7.5 7.7 5.1 7.7 0.0 4.2 6 0 0 6 6 6 0 Tetratricopeptide repeat Sec7 PF01369.15 AEO60264.1 - 5e-44 150.2 0.0 9.8e-44 149.2 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 AEO60264.1 - 2.9e-19 69.3 0.0 7.7e-19 68.0 0.0 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain Microtub_assoc PF07989.6 AEO60265.1 - 1.6e-19 69.5 8.9 1.6e-19 69.5 6.2 7.8 5 2 1 8 8 8 1 Microtubule associated Mto2_bdg PF12808.2 AEO60265.1 - 3.3e-07 30.2 13.2 3.3e-07 30.2 9.2 14.4 14 3 1 15 15 15 2 Micro-tubular organiser Mto1 C-term Mto2-binding region DegS PF05384.6 AEO60265.1 - 0.00031 19.9 2.7 0.00031 19.9 1.9 7.5 3 1 4 7 7 7 1 Sensor protein DegS IncA PF04156.9 AEO60265.1 - 0.0011 18.5 25.5 0.0011 18.5 17.7 8.5 3 2 5 8 8 8 3 IncA protein Filament PF00038.16 AEO60265.1 - 2.8 7.3 0.0 0.062 12.7 15.7 6.1 2 2 3 5 5 5 0 Intermediate filament protein MARVEL PF01284.18 AEO60266.1 - 2e-06 27.7 15.8 3.1e-06 27.0 11.0 1.2 1 0 0 1 1 1 1 Membrane-associating domain Arginase PF00491.16 AEO60267.1 - 2.6e-76 256.5 1.3 3.1e-76 256.3 0.9 1.0 1 0 0 1 1 1 1 Arginase family Glyco_transf_90 PF05686.7 AEO60268.1 - 2.7e-15 55.9 0.5 1.6e-08 33.6 0.0 3.1 3 0 0 3 3 3 3 Glycosyl transferase family 90 AAA_16 PF13191.1 AEO60269.1 - 1.1e-07 32.0 0.6 5.6e-07 29.7 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain RrnaAD PF00398.15 AEO60269.1 - 0.00024 20.2 0.0 0.00058 18.9 0.0 1.6 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase AAA_22 PF13401.1 AEO60269.1 - 0.00024 21.2 0.0 0.0013 18.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 AEO60269.1 - 0.00042 20.0 0.1 0.00095 18.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 AEO60269.1 - 0.058 13.7 0.0 0.18 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 AEO60269.1 - 0.064 13.5 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.17 AEO60269.1 - 0.15 12.2 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase UPF0079 PF02367.12 AEO60269.1 - 0.23 11.0 0.0 0.52 9.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 DUF2697 PF10906.3 AEO60270.1 - 0.01 15.7 0.1 0.023 14.6 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2697) Glyco_hydro_61 PF03443.9 AEO60271.1 - 3e-55 187.3 0.0 3.6e-55 187.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 p450 PF00067.17 AEO60272.1 - 6.7e-69 232.5 0.0 8.5e-69 232.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CBM_1 PF00734.13 AEO60273.1 - 2.1e-13 49.6 13.7 5.6e-13 48.2 9.5 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain SSP160 PF06933.6 AEO60273.1 - 3.4 5.5 20.8 5 4.9 14.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Sporozoite_P67 PF05642.6 AEO60273.1 - 6.2 4.5 11.5 7.4 4.3 8.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NPP1 PF05630.6 AEO60274.1 - 2e-81 272.6 1.1 2.4e-81 272.4 0.8 1.1 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) DUF946 PF06101.6 AEO60274.1 - 0.0085 14.1 0.3 0.012 13.6 0.2 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF946) EHN PF06441.7 AEO60275.1 - 1.6e-28 98.8 0.4 3.2e-28 97.8 0.1 1.6 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 AEO60275.1 - 1.5e-07 31.5 1.4 2.4e-07 30.8 0.3 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO60275.1 - 0.0016 18.0 0.0 0.0039 16.7 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Mito_carr PF00153.22 AEO60276.1 - 2e-17 62.6 1.9 1.3e-11 44.0 0.0 3.6 3 1 0 3 3 3 2 Mitochondrial carrier protein Methyltransf_23 PF13489.1 AEO60277.1 - 1.2e-17 64.0 0.0 1.7e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO60277.1 - 1.5e-08 35.2 0.0 2.1e-07 31.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO60277.1 - 4.8e-08 32.7 0.0 4.5e-07 29.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO60277.1 - 1.5e-05 25.3 0.0 0.00011 22.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO60277.1 - 3.9e-05 24.0 0.0 7.5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO60277.1 - 6e-05 23.3 0.0 0.00018 21.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO60277.1 - 0.024 14.6 0.0 0.11 12.5 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 AEO60277.1 - 0.036 14.0 0.0 0.083 12.8 0.0 1.6 2 0 0 2 2 2 0 FtsJ-like methyltransferase MTS PF05175.9 AEO60277.1 - 0.15 11.4 0.0 0.33 10.3 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_4 PF02390.12 AEO60277.1 - 0.18 10.8 0.0 0.41 9.6 0.0 1.5 2 0 0 2 2 2 0 Putative methyltransferase E3_binding PF02817.12 AEO60278.1 - 0.0027 17.3 0.3 0.0039 16.7 0.2 1.2 1 0 0 1 1 1 1 e3 binding domain DnaJ_CXXCXGXG PF00684.14 AEO60281.1 - 0.00018 21.5 3.6 0.001 19.0 2.4 2.0 1 1 0 1 1 1 1 DnaJ central domain Zn-ribbon_8 PF09723.5 AEO60281.1 - 0.017 15.0 0.4 3.5 7.6 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain zf-HIT PF04438.11 AEO60281.1 - 0.092 12.4 3.0 0.15 11.7 2.1 1.4 1 1 0 1 1 1 0 HIT zinc finger A2L_zn_ribbon PF08792.5 AEO60281.1 - 0.2 11.1 2.3 0.68 9.4 0.0 2.3 3 0 0 3 3 3 0 A2L zinc ribbon domain Prim_Zn_Ribbon PF08273.7 AEO60281.1 - 0.37 10.9 6.7 8.7 6.5 4.6 2.2 1 1 0 1 1 1 0 Zinc-binding domain of primase-helicase RRN7 PF11781.3 AEO60281.1 - 1.1 8.8 5.0 5.2 6.6 0.7 2.2 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 TF_Zn_Ribbon PF08271.7 AEO60281.1 - 1.2 8.5 5.7 7 6.0 3.9 2.0 1 1 0 1 1 1 0 TFIIB zinc-binding HMG_box PF00505.14 AEO60283.1 - 1.7e-06 28.2 0.0 3.5e-06 27.1 0.0 1.5 1 1 0 1 1 1 1 HMG (high mobility group) box MAT_Alpha1 PF04769.7 AEO60283.1 - 0.15 11.3 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 OTU PF02338.14 AEO60284.1 - 0.0029 18.1 0.1 0.0061 17.1 0.1 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease MOSC PF03473.12 AEO60286.1 - 0.17 11.3 0.4 14 5.1 0.1 2.4 2 1 0 2 2 2 0 MOSC domain Transformer PF06495.6 AEO60288.1 - 0.018 14.9 0.8 0.03 14.1 0.6 1.4 1 0 0 1 1 1 0 Fruit fly transformer protein SSP160 PF06933.6 AEO60288.1 - 0.046 11.7 3.0 0.061 11.2 2.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 CAF-1_p150 PF11600.3 AEO60288.1 - 0.094 12.0 6.6 0.13 11.5 4.6 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Dehydrin PF00257.14 AEO60288.1 - 0.33 11.2 5.4 0.048 14.0 0.7 1.8 2 0 0 2 2 2 0 Dehydrin APG6 PF04111.7 AEO60288.1 - 0.36 9.8 2.9 0.46 9.4 2.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 TFIIA PF03153.8 AEO60288.1 - 0.72 9.6 5.4 0.94 9.3 3.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.4 AEO60288.1 - 1.5 6.9 4.8 2.2 6.4 3.3 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF1635 PF07795.6 AEO60288.1 - 2.1 7.6 6.2 2.5 7.4 0.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1635) Cep57_CLD_2 PF14197.1 AEO60288.1 - 3 7.8 17.5 4.7 7.2 1.4 2.2 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 Helicase_C_2 PF13307.1 AEO60289.1 - 7.5e-58 195.1 0.0 1.4e-57 194.2 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 AEO60289.1 - 3.8e-26 91.5 0.0 6.1e-26 90.8 0.0 1.3 1 0 0 1 1 1 1 DEAD_2 Pkinase PF00069.20 AEO60290.1 - 1e-41 142.8 0.0 5.1e-38 130.6 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AEO60290.1 - 4.6e-14 52.1 0.0 4.6e-08 32.4 0.0 3.6 4 0 0 4 4 4 2 Protein tyrosine kinase APH PF01636.18 AEO60290.1 - 7.3e-05 22.6 0.1 0.022 14.4 0.0 3.2 2 2 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 AEO60290.1 - 0.00075 18.5 0.0 0.14 11.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like DXP_redisom_C PF08436.7 AEO60290.1 - 0.049 13.5 0.0 0.18 11.6 0.0 1.9 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal Cnd1_N PF12922.2 AEO60291.1 - 2.2e-57 193.4 0.0 2.2e-57 193.4 0.0 2.3 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.2 AEO60291.1 - 1e-56 191.6 2.1 8.3e-53 178.8 0.4 2.9 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 AEO60291.1 - 3.5e-10 40.0 4.1 0.00012 22.3 0.0 6.1 4 4 3 7 7 7 4 HEAT repeats HEAT PF02985.17 AEO60291.1 - 1.4e-07 30.9 11.9 0.17 12.0 0.0 6.9 8 0 0 8 8 8 3 HEAT repeat HEAT_EZ PF13513.1 AEO60291.1 - 5e-05 23.6 8.3 0.012 16.0 0.1 5.8 5 0 0 5 5 5 1 HEAT-like repeat Adaptin_N PF01602.15 AEO60291.1 - 0.00011 20.7 3.0 0.011 14.0 0.2 3.7 3 1 0 3 3 3 2 Adaptin N terminal region Cnd3 PF12719.2 AEO60291.1 - 0.00027 20.0 1.1 0.0023 16.9 0.1 2.7 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain DUF2435 PF10363.4 AEO60291.1 - 0.0048 16.7 0.0 0.66 9.9 0.0 3.4 3 1 0 3 3 3 1 Protein of unknown function (DUF2435) Cohesin_HEAT PF12765.2 AEO60291.1 - 0.054 13.4 0.0 6 6.9 0.0 3.5 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion GRIM-19 PF06212.7 AEO60292.1 - 3.5e-21 75.2 0.0 6.9e-21 74.3 0.0 1.4 1 1 0 1 1 1 1 GRIM-19 protein NIF PF03031.13 AEO60293.1 - 1.6e-27 96.1 0.3 4.9e-27 94.5 0.0 1.9 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 AEO60293.1 - 1.9e-07 30.7 0.0 5.8e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 AEO60293.1 - 2.4e-07 30.8 0.0 5.1e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Biotin_lipoyl PF00364.17 AEO60293.1 - 0.011 15.3 0.3 0.83 9.3 0.0 3.2 3 1 0 3 3 3 0 Biotin-requiring enzyme GRAM PF02893.15 AEO60294.1 - 5.7e-26 89.8 0.1 2e-15 56.0 0.0 3.4 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.15 AEO60294.1 - 1.2e-24 86.6 0.0 2.7e-24 85.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.24 AEO60294.1 - 1.2e-13 51.1 0.0 4.7e-13 49.2 0.0 2.1 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 AEO60294.1 - 5.8e-05 23.0 0.0 0.00014 21.8 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 AEO60294.1 - 0.00022 21.0 0.0 0.00044 20.1 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 AEO60294.1 - 0.0016 18.6 3.0 0.0037 17.5 0.4 2.7 2 1 0 2 2 2 1 Pleckstrin homology domain UDPGT PF00201.13 AEO60294.1 - 0.005 15.4 0.0 0.016 13.7 0.0 1.6 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_6 PF15406.1 AEO60294.1 - 0.076 13.0 0.0 0.25 11.4 0.0 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain WD40 PF00400.27 AEO60295.1 - 1.1e-12 47.2 6.4 0.00068 19.4 0.0 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat SR-25 PF10500.4 AEO60297.1 - 0.0025 17.3 9.1 0.0031 17.0 6.3 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Tmemb_cc2 PF10267.4 AEO60297.1 - 0.16 10.5 3.2 0.18 10.3 2.2 1.0 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Macoilin PF09726.4 AEO60297.1 - 0.86 7.8 5.1 0.87 7.7 3.5 1.0 1 0 0 1 1 1 0 Transmembrane protein Sporozoite_P67 PF05642.6 AEO60297.1 - 1.4 6.7 8.5 1.5 6.5 5.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Aminotran_3 PF00202.16 AEO60298.1 - 1.1e-54 185.6 0.0 1.4e-54 185.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III DegT_DnrJ_EryC1 PF01041.12 AEO60298.1 - 0.043 12.8 0.1 0.074 12.0 0.1 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Pneumo_matrix PF03393.11 AEO60301.1 - 0.041 12.8 0.0 0.045 12.6 0.0 1.0 1 0 0 1 1 1 0 Pneumovirus matrix protein RuBisCO_large_N PF02788.11 AEO60302.1 - 0.056 13.1 0.3 0.086 12.5 0.2 1.3 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, N-terminal domain ADIP PF11559.3 AEO60303.1 - 0.14 12.0 8.1 0.54 10.1 1.9 2.8 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.4 AEO60303.1 - 0.26 11.1 6.0 0.24 11.2 0.9 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF972 PF06156.8 AEO60303.1 - 0.41 11.0 2.1 3.2 8.1 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF972) TBPIP PF07106.8 AEO60303.1 - 0.56 9.7 5.4 3.1 7.3 1.4 2.3 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 AEO60303.1 - 0.96 9.0 6.3 6.8 6.2 1.8 2.3 2 0 0 2 2 2 0 IncA protein HOOK PF05622.7 AEO60303.1 - 1.6 6.4 8.4 6.3 4.4 3.7 2.2 2 0 0 2 2 2 0 HOOK protein DivIC PF04977.10 AEO60303.1 - 3 7.3 11.3 0.44 10.0 4.6 1.9 2 0 0 2 2 2 0 Septum formation initiator FlgN PF05130.7 AEO60304.1 - 0.0051 17.0 1.4 0.0081 16.4 1.0 1.4 1 0 0 1 1 1 1 FlgN protein APG6 PF04111.7 AEO60304.1 - 0.0056 15.7 0.5 0.0069 15.4 0.3 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 OmpH PF03938.9 AEO60304.1 - 0.036 13.9 0.4 0.047 13.6 0.3 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1599 PF07659.6 AEO60304.1 - 0.086 12.9 2.6 5.7 7.0 0.1 2.3 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1599) DUF1664 PF07889.7 AEO60304.1 - 0.15 11.8 0.3 0.23 11.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Fzo_mitofusin PF04799.8 AEO60304.1 - 0.2 11.0 1.1 0.29 10.5 0.8 1.2 1 0 0 1 1 1 0 fzo-like conserved region DUF724 PF05266.9 AEO60304.1 - 0.22 11.1 3.0 0.61 9.6 2.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF724) CALCOCO1 PF07888.6 AEO60304.1 - 1.5 7.0 9.3 1.9 6.7 6.5 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2852 PF11014.3 AEO60304.1 - 2.5 8.0 6.2 2.6 8.0 3.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) Ribosomal_60s PF00428.14 AEO60305.1 - 6.3 7.2 7.3 6.4 7.2 3.9 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein Peroxidase_2 PF01328.12 AEO60306.1 - 7e-47 159.6 0.2 9.4e-47 159.2 0.1 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 SE PF08491.5 AEO60308.1 - 3.9e-05 22.6 0.0 3.9e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase ADH_zinc_N PF00107.21 AEO60309.1 - 4.7e-29 100.5 0.2 8e-29 99.8 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 AEO60309.1 - 5.9e-16 59.5 0.0 1.6e-15 58.1 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AEO60309.1 - 2.9e-11 43.1 0.0 9.5e-11 41.4 0.0 2.0 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 AEO60309.1 - 0.0031 17.5 0.0 0.0073 16.2 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_7 PF13241.1 AEO60309.1 - 0.084 13.1 0.1 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Glyco_hydro_2_N PF02837.13 AEO60310.1 - 8.8e-07 28.6 0.1 1.9e-06 27.5 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 AEO60310.1 - 1e-06 29.1 0.4 3.6e-06 27.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 TPR_12 PF13424.1 AEO60311.1 - 0.007 16.2 0.3 1.7 8.6 0.0 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat DUF3989 PF13150.1 AEO60311.1 - 0.022 14.2 0.1 0.039 13.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3989) TPR_2 PF07719.12 AEO60311.1 - 0.028 14.3 1.3 30 4.8 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Caleosin PF05042.8 AEO60313.1 - 1.9e-56 190.3 0.0 2.4e-56 190.0 0.0 1.1 1 0 0 1 1 1 1 Caleosin related protein EF-hand_6 PF13405.1 AEO60313.1 - 0.0041 16.8 0.3 6.7 6.8 0.0 3.4 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.27 AEO60313.1 - 0.049 12.9 0.2 33 4.1 0.0 3.3 3 0 0 3 3 3 0 EF hand EF-hand_7 PF13499.1 AEO60313.1 - 0.053 13.6 0.1 9.4 6.4 0.0 3.0 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_5 PF13202.1 AEO60313.1 - 0.37 10.2 2.0 4.3 6.8 0.0 2.9 3 0 0 3 3 3 0 EF hand Sulfotransfer_3 PF13469.1 AEO60314.1 - 0.019 15.8 0.4 0.041 14.8 0.3 1.6 1 1 0 1 1 1 0 Sulfotransferase family MFS_1 PF07690.11 AEO60318.1 - 1.5e-18 66.7 69.8 9.7e-17 60.7 27.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3432 PF11914.3 AEO60318.1 - 0.74 9.8 4.3 3 7.9 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3432) ADH_zinc_N PF00107.21 AEO60320.1 - 5.2e-19 68.0 0.0 8e-19 67.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 AEO60320.1 - 2e-06 28.7 0.0 4.1e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.9 AEO60322.1 - 1.8e-06 27.9 0.0 1.2e-05 25.3 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 AEO60322.1 - 0.0024 17.6 0.0 0.15 11.8 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 AEO60322.1 - 0.0085 16.1 0.0 0.13 12.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 AEO60322.1 - 0.062 12.1 0.0 0.19 10.5 0.0 1.8 1 1 1 2 2 2 0 FAD dependent oxidoreductase Fungal_trans_2 PF11951.3 AEO60323.1 - 7e-14 51.2 1.0 7.9e-14 51.0 0.7 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Lactamase_B PF00753.22 AEO60324.1 - 3.7e-19 69.1 5.1 7.5e-19 68.1 3.5 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 AEO60324.1 - 0.008 15.7 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF3112 PF11309.3 AEO60325.1 - 6.2e-14 52.1 0.2 2.4e-13 50.1 0.0 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF3112) TPR_11 PF13414.1 AEO60326.1 - 2.1e-11 43.2 11.3 2e-08 33.7 0.8 2.5 2 0 0 2 2 2 2 TPR repeat SET PF00856.23 AEO60326.1 - 6.5e-10 39.5 0.0 2.6e-09 37.5 0.0 2.0 1 0 0 1 1 1 1 SET domain TPR_2 PF07719.12 AEO60326.1 - 2.7e-06 26.8 8.7 0.0058 16.4 0.3 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 AEO60326.1 - 0.0017 17.8 4.7 3.1 7.5 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 AEO60326.1 - 0.18 12.5 11.2 0.12 13.0 2.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 AEO60326.1 - 0.41 10.6 11.3 3.4 7.6 0.9 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat LytR_C PF13399.1 AEO60326.1 - 2.4 8.5 5.4 17 5.8 0.0 3.7 4 0 0 4 4 4 0 LytR cell envelope-related transcriptional attenuator TPR_16 PF13432.1 AEO60326.1 - 3 8.6 24.9 0.42 11.3 2.9 3.5 2 1 2 4 4 4 0 Tetratricopeptide repeat p450 PF00067.17 AEO60327.1 - 3.2e-45 154.5 0.0 3.7e-45 154.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF202 PF02656.10 AEO60329.1 - 4.3 7.6 7.0 1.5e+02 2.6 4.8 3.1 1 1 0 1 1 1 0 Domain of unknown function (DUF202) MFS_1 PF07690.11 AEO60330.1 - 7.3e-24 84.1 67.7 8.5e-19 67.4 31.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Mac PF12464.3 AEO60330.1 - 1.8e-21 75.8 0.1 3.2e-21 75.0 0.1 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase DUF1228 PF06779.9 AEO60330.1 - 0.00085 19.3 10.7 0.98 9.4 0.2 4.1 4 0 0 4 4 4 3 Protein of unknown function (DUF1228) Zn_clus PF00172.13 AEO60331.1 - 1.1e-09 38.0 8.9 1.7e-09 37.4 6.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 AEO60331.1 - 6.4e-07 28.4 0.2 1.2e-06 27.6 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Spt20 PF12090.3 AEO60331.1 - 0.01 15.2 1.5 0.018 14.3 1.0 1.4 1 0 0 1 1 1 0 Spt20 family Suf PF05843.9 AEO60331.1 - 0.011 15.5 4.2 0.022 14.4 2.9 1.6 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Ndc1_Nup PF09531.5 AEO60331.1 - 0.32 9.3 7.5 0.6 8.4 5.2 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Molydop_binding PF01568.16 AEO60332.1 - 8.2e-10 38.4 0.3 6.4e-09 35.6 0.1 2.1 1 1 1 2 2 2 1 Molydopterin dinucleotide binding domain AflR PF08493.5 AEO60335.1 - 2.4e-28 98.9 3.5 2.4e-28 98.9 2.4 2.5 1 1 1 2 2 2 1 Aflatoxin regulatory protein FAP PF07174.6 AEO60335.1 - 9.7 5.3 23.3 17 4.5 16.2 1.3 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) adh_short PF00106.20 AEO60336.1 - 9e-31 107.0 0.3 1.2e-30 106.6 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO60336.1 - 2.4e-20 73.3 0.0 3.2e-20 72.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO60336.1 - 5.1e-16 58.8 0.1 7.2e-16 58.3 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 AEO60336.1 - 2.2e-07 31.0 0.1 3.4e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 AEO60336.1 - 8.6e-05 21.8 0.0 0.00012 21.3 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 AEO60336.1 - 0.0014 18.4 0.1 0.024 14.3 0.0 2.6 3 0 0 3 3 3 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RmlD_sub_bind PF04321.12 AEO60336.1 - 0.0015 17.4 0.0 0.0027 16.6 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Phage_fiber_2 PF03406.8 AEO60336.1 - 2 8.1 4.3 6.8 6.4 0.0 2.7 3 0 0 3 3 3 0 Phage tail fibre repeat adh_short PF00106.20 AEO60337.1 - 3.9e-20 72.4 0.1 6.2e-20 71.7 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO60337.1 - 1.6e-09 37.8 0.1 2.1e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO60337.1 - 1.7e-06 27.8 0.3 4.2e-06 26.5 0.2 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 AEO60337.1 - 7.9e-05 22.7 0.3 0.00015 21.8 0.2 1.5 1 0 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 AEO60337.1 - 0.012 15.3 0.5 0.079 12.7 0.3 2.2 1 1 1 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase APH PF01636.18 AEO60339.1 - 0.0041 16.8 1.3 0.0083 15.8 0.9 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 AEO60339.1 - 0.0052 15.8 0.2 0.0091 15.0 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RPE65 PF03055.10 AEO60340.1 - 1.3e-127 426.3 0.0 1.5e-127 426.1 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein SnoaL_4 PF13577.1 AEO60341.1 - 4.3e-26 91.2 1.3 5.7e-26 90.9 0.9 1.2 1 0 0 1 1 1 1 SnoaL-like domain DivIC PF04977.10 AEO60341.1 - 0.058 12.8 0.8 0.097 12.1 0.6 1.3 1 0 0 1 1 1 0 Septum formation initiator FlxA PF14282.1 AEO60341.1 - 0.21 11.5 0.4 0.3 11.0 0.3 1.2 1 0 0 1 1 1 0 FlxA-like protein DUF4140 PF13600.1 AEO60341.1 - 0.24 11.8 0.9 0.37 11.2 0.6 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF1192 PF06698.6 AEO60341.1 - 0.28 11.0 0.8 0.51 10.1 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DUF3328 PF11807.3 AEO60344.1 - 3.6e-21 75.8 1.0 4.7e-21 75.4 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Pectate_lyase_3 PF12708.2 AEO60346.1 - 1.8e-37 129.6 4.8 2.8e-24 86.4 1.4 2.5 2 0 0 2 2 2 2 Pectate lyase superfamily protein Beta_helix PF13229.1 AEO60346.1 - 0.0038 16.9 4.9 0.0061 16.3 2.5 2.0 2 0 0 2 2 2 1 Right handed beta helix region Pkinase PF00069.20 AEO60347.1 - 1e-25 90.3 0.0 2.1e-25 89.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO60347.1 - 0.00017 20.7 0.0 0.00023 20.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 AEO60347.1 - 0.0016 17.5 0.0 0.0024 16.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AEO60347.1 - 0.021 14.5 0.1 0.11 12.1 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family adh_short PF00106.20 AEO60348.1 - 0.0027 17.6 0.0 0.95 9.3 0.0 2.9 2 1 1 3 3 3 2 short chain dehydrogenase Tyrosinase PF00264.15 AEO60349.1 - 3.9e-30 105.6 0.3 8.3e-30 104.5 0.1 1.5 1 1 0 1 1 1 1 Common central domain of tyrosinase Mid2 PF04478.7 AEO60350.1 - 0.015 14.7 0.1 0.048 13.0 0.1 1.8 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor NCU-G1 PF15065.1 AEO60350.1 - 0.016 13.8 0.8 0.069 11.8 0.2 2.1 2 0 0 2 2 2 0 Lysosomal transcription factor, NCU-G1 DUF4029 PF13221.1 AEO60351.1 - 0.015 15.6 0.3 5 7.5 0.1 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF4029) Endomucin PF07010.7 AEO60351.1 - 0.11 11.8 0.6 0.16 11.2 0.4 1.2 1 0 0 1 1 1 0 Endomucin DUF308 PF03729.8 AEO60351.1 - 0.46 10.4 6.8 1.3 9.0 1.9 2.4 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) adh_short PF00106.20 AEO60352.1 - 1.8e-15 57.2 6.2 4.6e-14 52.6 4.3 2.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO60352.1 - 9.6e-12 45.1 0.0 2.8e-05 24.0 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO60352.1 - 5.8e-09 35.8 0.7 5.8e-09 35.8 0.5 1.6 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.15 AEO60352.1 - 0.13 12.3 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Rieske PF00355.21 AEO60353.1 - 3.8e-12 45.6 0.0 4.8e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pkinase PF00069.20 AEO60354.1 - 1.8e-08 33.8 0.0 2.4e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 AEO60354.1 - 2.8e-05 23.3 0.0 4.3e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.6 AEO60354.1 - 0.0066 15.6 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) APH PF01636.18 AEO60354.1 - 0.0067 16.1 0.3 0.014 15.1 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 AEO60354.1 - 0.0072 15.4 0.0 0.01 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase ATG16 PF08614.6 AEO60355.1 - 0.00062 19.6 23.2 0.0019 18.0 5.6 7.5 1 1 4 7 7 7 4 Autophagy protein 16 (ATG16) Filament PF00038.16 AEO60355.1 - 0.0068 15.9 8.0 0.0068 15.9 5.5 7.2 2 2 2 6 6 6 3 Intermediate filament protein Nsp1_C PF05064.8 AEO60355.1 - 0.0098 15.5 2.7 0.0098 15.5 1.9 4.9 3 2 1 4 4 4 1 Nsp1-like C-terminal region Reo_sigmaC PF04582.7 AEO60355.1 - 0.033 13.3 31.0 0.043 13.0 4.5 4.7 2 2 3 5 5 5 0 Reovirus sigma C capsid protein GAS PF13851.1 AEO60355.1 - 0.034 13.3 0.2 0.034 13.3 0.2 7.1 3 2 3 7 7 7 0 Growth-arrest specific micro-tubule binding AT_hook PF02178.14 AEO60355.1 - 0.13 12.0 7.3 0.37 10.5 5.0 1.9 1 0 0 1 1 1 0 AT hook motif Fic PF02661.13 AEO60356.1 - 9.6e-18 64.6 0.0 2.4e-17 63.4 0.0 1.7 1 0 0 1 1 1 1 Fic/DOC family Fungal_trans PF04082.13 AEO60357.1 - 6.6e-16 57.9 0.0 1e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO60357.1 - 8.5e-09 35.1 12.4 1.5e-08 34.3 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PCMT PF01135.14 AEO60359.1 - 4.7e-59 199.4 0.0 5.8e-59 199.1 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 AEO60359.1 - 4.1e-08 33.8 0.0 5.9e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO60359.1 - 2.7e-05 23.7 0.0 3.6e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO60359.1 - 4.5e-05 23.4 0.1 9.8e-05 22.3 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 AEO60359.1 - 0.00025 20.7 0.0 0.00038 20.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO60359.1 - 0.0034 17.1 0.0 0.0045 16.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AEO60359.1 - 0.011 15.1 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.13 AEO60359.1 - 0.014 14.5 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family RrnaAD PF00398.15 AEO60359.1 - 0.058 12.4 0.0 0.079 11.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_3 PF01596.12 AEO60359.1 - 0.061 12.3 0.0 0.079 11.9 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_24 PF13578.1 AEO60359.1 - 0.083 13.7 0.2 0.7 10.7 0.0 2.3 1 1 1 2 2 2 0 Methyltransferase domain Fibrillarin PF01269.12 AEO60359.1 - 0.095 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin Methyltransf_11 PF08241.7 AEO60359.1 - 0.1 13.1 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF2370 PF10176.4 AEO60360.1 - 5.7e-85 284.3 0.2 1.2e-84 283.2 0.0 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF2370) DUF202 PF02656.10 AEO60360.1 - 0.057 13.6 0.5 0.35 11.1 0.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Mito_carr PF00153.22 AEO60362.1 - 2.6e-54 180.8 6.6 4.1e-22 77.7 0.2 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Hemerythrin PF01814.18 AEO60364.1 - 1.3e-15 57.6 4.8 1.8e-15 57.2 3.4 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DUF2361 PF10153.4 AEO60364.1 - 1.4 9.1 6.0 5.5 7.2 0.0 2.9 1 1 2 3 3 3 0 Uncharacterised conserved protein (DUF2361) zf-C2H2_2 PF12756.2 AEO60364.1 - 10 6.3 6.9 3.4 7.8 1.3 2.5 2 1 0 3 3 3 0 C2H2 type zinc-finger (2 copies) Acetyltransf_1 PF00583.19 AEO60368.1 - 1.4e-18 66.7 0.0 2e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 AEO60368.1 - 2.2e-11 43.8 0.1 2.5e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 AEO60368.1 - 2.4e-07 30.3 0.0 3.5e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 AEO60368.1 - 8.9e-07 29.1 0.0 1e-06 28.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 AEO60368.1 - 1.6e-06 28.2 0.0 2.1e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 AEO60368.1 - 3.2e-05 23.8 0.0 4.8e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 AEO60368.1 - 4.1e-05 23.5 0.0 5.2e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 AEO60368.1 - 0.00015 21.5 0.0 0.00024 20.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 AEO60368.1 - 0.0015 18.3 0.0 0.0027 17.5 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase DUF3749 PF12568.3 AEO60368.1 - 0.0023 17.5 0.0 0.0032 17.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 AEO60368.1 - 0.079 12.7 0.0 0.079 12.7 0.0 1.6 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase Cys_Met_Meta_PP PF01053.15 AEO60369.1 - 8.1e-23 80.3 0.0 1.3e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 AEO60369.1 - 0.0074 15.2 0.0 0.024 13.6 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class I and II Oxidored_q6 PF01058.17 AEO60370.1 - 0.035 13.7 0.0 0.044 13.4 0.0 1.3 1 1 0 1 1 1 0 NADH ubiquinone oxidoreductase, 20 Kd subunit Glyco_transf_20 PF00982.16 AEO60371.1 - 6.9e-150 499.6 0.0 9.2e-150 499.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 AEO60371.1 - 1.4e-75 253.2 0.0 3.2e-75 252.0 0.0 1.6 2 0 0 2 2 2 1 Trehalose-phosphatase Glycos_transf_1 PF00534.15 AEO60371.1 - 0.052 12.9 0.0 0.29 10.5 0.0 2.2 1 1 0 1 1 1 0 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 AEO60371.1 - 0.056 13.6 0.0 0.23 11.6 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferases group 1 Methyltransf_2 PF00891.13 AEO60372.1 - 1.3e-21 76.8 0.1 2.9e-21 75.7 0.1 1.5 2 0 0 2 2 2 1 O-methyltransferase GFA PF04828.9 AEO60373.1 - 1.5e-10 40.9 0.8 1.5e-10 40.9 0.5 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme AA_permease_2 PF13520.1 AEO60374.1 - 3.2e-94 315.8 40.3 4.1e-94 315.5 28.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 AEO60374.1 - 5.2e-20 71.2 30.4 9.2e-20 70.4 21.1 1.4 1 1 0 1 1 1 1 Amino acid permease MFS_1 PF07690.11 AEO60375.1 - 5.7e-20 71.3 44.1 2.6e-11 42.8 14.6 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 AEO60375.1 - 0.00015 20.3 20.5 0.084 11.2 6.3 2.6 1 1 1 2 2 2 2 MFS/sugar transport protein Nuc_H_symport PF03825.11 AEO60375.1 - 0.65 8.7 13.2 0.012 14.4 2.4 2.1 2 0 0 2 2 2 0 Nucleoside H+ symporter Sugar_tr PF00083.19 AEO60376.1 - 5.9e-94 315.1 18.3 6.9e-94 314.9 12.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO60376.1 - 7.1e-31 107.1 38.3 1.9e-27 95.9 18.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_2 PF04550.7 AEO60376.1 - 0.031 14.3 1.2 0.31 11.1 0.4 2.5 2 0 0 2 2 2 0 Phage holin family 2 DUF1218 PF06749.7 AEO60376.1 - 0.045 14.2 3.1 0.28 11.6 0.2 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1218) Rab5ip PF07019.7 AEO60376.1 - 3.9 7.6 10.9 0.17 12.0 1.6 3.2 3 0 0 3 3 3 0 Rab5-interacting protein (Rab5ip) Glyoxalase_2 PF12681.2 AEO60377.1 - 9.7e-10 39.0 0.1 1.1e-09 38.7 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 AEO60377.1 - 0.0004 20.3 0.0 0.00061 19.7 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Vmethyltransf PF01660.12 AEO60379.1 - 1.3e-15 56.9 0.2 1.6e-15 56.6 0.1 1.1 1 0 0 1 1 1 1 Viral methyltransferase TK PF00265.13 AEO60379.1 - 0.047 13.2 0.4 1.3 8.5 0.0 2.1 1 1 1 2 2 2 0 Thymidine kinase DUF1010 PF06231.6 AEO60381.1 - 0.035 14.1 0.9 0.075 13.0 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1010) F-box PF00646.28 AEO60382.1 - 0.021 14.5 0.2 0.058 13.0 0.2 1.7 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.2 AEO60382.1 - 1.6 8.5 5.7 0.13 12.0 0.2 2.0 2 0 0 2 2 2 0 F-box-like 2-Hacid_dh_C PF02826.14 AEO60383.1 - 1.1e-42 145.2 0.0 2e-28 98.7 0.0 2.1 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 AEO60383.1 - 0.0013 18.7 0.0 0.0026 17.7 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_2 PF03446.10 AEO60383.1 - 0.0052 16.6 0.0 0.0084 15.9 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox PF00070.22 AEO60383.1 - 0.0077 16.6 0.0 0.014 15.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase XdhC_C PF13478.1 AEO60383.1 - 0.01 16.1 0.0 0.023 14.9 0.0 1.6 1 1 0 1 1 1 0 XdhC Rossmann domain 3HCDH_N PF02737.13 AEO60383.1 - 0.025 14.2 0.0 0.037 13.6 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 AEO60383.1 - 0.029 14.7 0.0 0.1 13.0 0.0 2.0 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 AEO60383.1 - 0.093 12.4 0.0 0.17 11.6 0.0 1.4 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.13 AEO60383.1 - 0.11 12.4 0.0 0.24 11.4 0.0 1.7 1 1 0 1 1 1 0 TrkA-N domain GFA PF04828.9 AEO60384.1 - 2.1e-16 59.6 0.5 3.5e-16 58.9 0.4 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.1 AEO60384.1 - 0.0036 16.9 0.3 0.0036 16.9 0.2 3.2 4 0 0 4 4 4 1 Nudix N-terminal Cys_rich_CWC PF14375.1 AEO60384.1 - 0.28 11.1 6.6 0.16 11.9 2.3 2.1 2 0 0 2 2 2 0 Cysteine-rich CWC Glyco_hydro_11 PF00457.12 AEO60385.1 - 1.7e-07 30.7 3.6 2e-07 30.5 2.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Glyco_hydro_11 PF00457.12 AEO60386.1 - 4.3e-50 169.5 3.8 5.2e-50 169.3 2.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 EI24 PF07264.6 AEO60387.1 - 2.7e-05 23.7 8.3 3.7e-05 23.2 0.1 2.3 2 0 0 2 2 2 2 Etoposide-induced protein 2.4 (EI24) DUF805 PF05656.9 AEO60387.1 - 4.8 7.0 8.5 0.86 9.4 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF805) Glyco_hydro_16 PF00722.16 AEO60389.1 - 1.1e-16 60.6 2.6 2e-16 59.7 1.4 1.8 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 AEO60389.1 - 3e-09 35.5 1.2 4.3e-06 25.1 0.1 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) MFS_1 PF07690.11 AEO60390.1 - 3.1e-19 68.9 44.9 7.1e-18 64.4 18.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily HET PF06985.6 AEO60391.1 - 9e-11 42.0 0.0 1.2e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ketoacyl-synt PF00109.21 AEO60392.1 - 1.2e-63 214.9 0.0 1.2e-63 214.9 0.0 2.4 3 0 0 3 3 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 AEO60392.1 - 1.4e-56 191.0 0.1 6.3e-56 188.8 0.1 2.2 3 0 0 3 3 2 1 KR domain PS-DH PF14765.1 AEO60392.1 - 7.6e-52 176.3 2.6 1.4e-51 175.4 1.5 1.7 2 0 0 2 2 2 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 AEO60392.1 - 6.9e-47 160.3 0.1 1.3e-46 159.4 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 AEO60392.1 - 1e-41 142.6 0.1 7.1e-41 139.9 0.1 2.6 2 0 0 2 2 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 AEO60392.1 - 7.6e-37 125.7 0.2 2.3e-36 124.2 0.0 2.0 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 AEO60392.1 - 6.9e-16 58.5 0.0 3.7e-15 56.1 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 AEO60392.1 - 2.1e-10 41.5 0.0 2.6e-09 38.0 0.0 3.0 3 0 0 3 3 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 AEO60392.1 - 4.5e-10 39.1 0.1 1.8e-09 37.2 0.1 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 AEO60392.1 - 1.7e-09 37.6 0.0 4.4e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO60392.1 - 4.4e-07 29.6 0.0 9.7e-07 28.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO60392.1 - 2e-06 28.3 0.0 8.9e-06 26.2 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 AEO60392.1 - 4.2e-06 26.9 0.0 1.1e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.7 AEO60392.1 - 1.8e-05 25.1 0.0 0.0012 19.2 0.0 3.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO60392.1 - 2.9e-05 24.0 0.5 0.00014 21.8 0.3 2.3 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 AEO60392.1 - 0.00078 19.1 0.0 0.0023 17.6 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Shikimate_DH PF01488.15 AEO60392.1 - 0.19 11.8 0.0 0.39 10.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PCMT PF01135.14 AEO60392.1 - 0.38 10.2 0.1 2 7.9 0.0 2.1 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Polysacc_synt_2 PF02719.10 AEO60392.1 - 1.5 7.6 0.0 3 6.6 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein E1-E2_ATPase PF00122.15 AEO60393.1 - 2.5e-64 216.4 1.1 2.5e-64 216.4 0.8 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 AEO60393.1 - 1.9e-32 113.4 0.0 2.8e-30 106.3 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 AEO60393.1 - 5.6e-31 107.4 6.1 5.6e-31 107.4 4.2 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 AEO60393.1 - 1.3e-17 63.4 0.0 2.8e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 AEO60393.1 - 6.2e-15 55.8 0.0 1.9e-14 54.2 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 AEO60393.1 - 3e-14 52.2 0.3 1.4e-13 50.0 0.0 2.4 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 AEO60393.1 - 0.00049 19.7 0.3 0.0025 17.4 0.3 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase SieB PF14163.1 AEO60393.1 - 0.023 14.2 1.8 0.023 14.2 0.1 1.8 2 0 0 2 2 2 0 Superinfection exclusion protein B DUF1857 PF08982.6 AEO60397.1 - 9.7e-44 148.5 0.0 1.3e-43 148.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) CFEM PF05730.6 AEO60398.1 - 1.9e-09 37.2 9.4 3.4e-09 36.3 6.5 1.4 1 0 0 1 1 1 1 CFEM domain PCNP PF15473.1 AEO60399.1 - 0.035 14.4 0.1 0.068 13.4 0.0 1.4 1 0 0 1 1 1 0 PEST, proteolytic signal-containing nuclear protein family SNARE_assoc PF09335.6 AEO60401.1 - 2.1e-19 69.9 10.8 3.1e-19 69.3 6.7 1.9 2 0 0 2 2 2 1 SNARE associated Golgi protein WBP-1 PF11669.3 AEO60401.1 - 0.0042 17.1 0.4 0.15 12.1 0.0 2.7 2 0 0 2 2 2 1 WW domain-binding protein 1 DUF3278 PF11683.3 AEO60401.1 - 0.0055 16.6 1.1 0.087 12.8 0.1 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF3278) AIF-MLS PF14962.1 AEO60401.1 - 0.048 13.3 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Mitochondria Localisation Sequence SpoIIIAH PF12685.2 AEO60401.1 - 0.061 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF948 PF06103.6 AEO60401.1 - 0.1 12.4 2.8 1.7 8.5 0.2 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1469 PF07332.6 AEO60401.1 - 0.36 10.5 14.9 1.1 9.0 0.9 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1469) Abhydrolase_9_N PF15420.1 AEO60401.1 - 1.9 8.2 9.6 1.1 8.9 0.1 2.9 1 1 2 3 3 3 0 Alpha/beta-hydrolase family N-terminus DUF3671 PF12420.3 AEO60401.1 - 3.8 7.5 7.0 22 5.0 1.9 2.2 2 0 0 2 2 2 0 Protein of unknown function Vpu PF00558.14 AEO60401.1 - 4.7 6.8 5.9 2.8 7.5 0.1 2.6 2 0 0 2 2 2 0 Vpu protein FAD_binding_3 PF01494.14 AEO60402.1 - 2.1e-47 161.8 0.0 3e-47 161.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 AEO60402.1 - 2.4e-05 24.2 0.1 7.1e-05 22.7 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 AEO60402.1 - 0.00021 19.8 0.1 0.00031 19.3 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 AEO60402.1 - 0.00024 20.1 0.4 0.0016 17.4 0.2 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.12 AEO60402.1 - 0.0003 19.9 0.0 0.00054 19.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 AEO60402.1 - 0.00037 19.4 0.2 0.0035 16.3 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 AEO60402.1 - 0.00066 18.6 0.3 0.0011 17.8 0.2 1.3 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 AEO60402.1 - 0.01 15.9 0.1 0.035 14.1 0.1 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AEO60402.1 - 0.011 16.1 0.0 0.048 14.0 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 AEO60402.1 - 0.012 15.5 0.1 0.016 15.1 0.1 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 AEO60402.1 - 0.065 11.8 1.0 1.8 7.1 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.17 AEO60402.1 - 0.081 11.7 0.2 0.11 11.3 0.1 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 AEO60402.1 - 0.22 11.1 0.0 0.39 10.3 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain COG5 PF10392.4 AEO60403.1 - 4.7e-41 139.8 3.0 7.8e-41 139.1 1.2 2.1 2 0 0 2 2 2 1 Golgi transport complex subunit 5 PaaX_C PF08223.6 AEO60403.1 - 0.0027 17.4 0.4 0.079 12.6 0.3 2.3 2 0 0 2 2 2 1 PaaX-like protein C-terminal domain NPV_P10 PF05531.7 AEO60403.1 - 0.029 14.6 2.3 1.4 9.1 0.4 3.2 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein SR-25 PF10500.4 AEO60403.1 - 0.62 9.5 16.5 1.7 8.0 2.1 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF4164 PF13747.1 AEO60403.1 - 0.68 10.1 4.8 0.81 9.8 1.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) SlyX PF04102.7 AEO60403.1 - 1.3 9.4 4.1 1.8 9.0 1.2 2.4 2 1 1 3 3 3 0 SlyX DUF1117 PF06547.7 AEO60403.1 - 1.6 8.8 16.5 0.11 12.6 1.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1117) DUF4525 PF15027.1 AEO60403.1 - 2.3 7.7 5.1 0.48 9.9 0.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4525) DUF2051 PF09738.4 AEO60403.1 - 2.9 7.1 11.4 12 5.0 0.3 3.1 2 1 1 3 3 3 0 Double stranded RNA binding protein (DUF2051) DUF3446 PF11928.3 AEO60403.1 - 6.4 7.0 22.6 3.1 8.0 2.2 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) IATP PF04568.7 AEO60403.1 - 7.8 6.5 6.7 0.9 9.5 1.1 2.1 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP DUF2434 PF10361.4 AEO60404.1 - 5.6e-133 442.5 4.7 7.7e-133 442.1 3.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) zf-C2H2_4 PF13894.1 AEO60405.1 - 3.2e-06 27.0 12.7 0.00054 20.1 1.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AEO60405.1 - 6e-06 26.2 4.0 6e-06 26.2 2.8 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 AEO60405.1 - 1.2e-05 25.3 11.4 0.006 16.8 0.9 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type bZIP_C PF12498.3 AEO60405.1 - 4.2 8.6 7.0 2.9 9.1 0.4 3.5 3 0 0 3 3 3 0 Basic leucine-zipper C terminal Colipase PF01114.13 AEO60407.1 - 0.062 12.8 5.3 0.1 12.0 3.7 1.3 1 0 0 1 1 1 0 Colipase, N-terminal domain APH PF01636.18 AEO60408.1 - 2.7e-11 43.6 0.0 3.4e-10 40.0 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 AEO60408.1 - 9.3e-05 22.0 0.0 0.00014 21.5 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RTA1 PF04479.8 AEO60409.1 - 3.7e-37 127.9 1.6 4.9e-37 127.5 1.1 1.1 1 0 0 1 1 1 1 RTA1 like protein BCD PF15461.1 AEO60409.1 - 0.0089 15.4 1.0 0.0089 15.4 0.7 2.2 1 1 1 2 2 2 1 Beta-carotene 15,15'-dioxygenase AzlD PF05437.7 AEO60409.1 - 0.28 11.1 10.2 0.21 11.5 0.4 3.4 3 1 0 3 3 3 0 Branched-chain amino acid transport protein (AzlD) Fungal_trans_2 PF11951.3 AEO60410.1 - 0.0067 15.0 0.0 0.011 14.2 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF2946 PF11162.3 AEO60410.1 - 0.074 13.2 1.2 0.18 11.9 0.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2946) DHDPS PF00701.17 AEO60412.1 - 1.7e-26 92.5 0.0 2e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Pkinase PF00069.20 AEO60413.1 - 1.5e-15 57.0 0.0 6.7e-15 54.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO60413.1 - 7.1e-14 51.4 0.0 9.6e-14 51.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO60413.1 - 9.8e-05 21.4 0.0 0.00014 20.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AEO60413.1 - 0.034 13.8 0.0 0.045 13.4 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family EBP PF05241.7 AEO60415.1 - 2.7e-62 209.2 8.0 3.4e-62 208.9 5.5 1.0 1 0 0 1 1 1 1 Emopamil binding protein Isochorismatase PF00857.15 AEO60416.1 - 4e-22 78.9 0.0 4.5e-22 78.7 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family HTH_33 PF13592.1 AEO60417.1 - 0.032 13.7 0.0 0.086 12.3 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn helix Rhomboid_SP PF12595.3 AEO60418.1 - 0.021 14.4 3.5 0.03 13.9 2.4 1.3 1 0 0 1 1 1 0 Rhomboid serine protease Med3 PF11593.3 AEO60418.1 - 0.17 11.1 1.3 0.17 11.1 0.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF1996 PF09362.5 AEO60419.1 - 1.7e-84 283.1 6.9 2.3e-84 282.7 1.8 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF1996) p450 PF00067.17 AEO60420.1 - 2.3e-09 36.3 1.1 3.1e-09 35.8 0.8 1.1 1 0 0 1 1 1 1 Cytochrome P450 ABC_membrane PF00664.18 AEO60421.1 - 5.4e-38 130.9 13.9 6.8e-38 130.6 9.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 AEO60421.1 - 2.9e-32 111.8 0.0 7.1e-32 110.5 0.0 1.7 2 0 0 2 2 1 1 ABC transporter SMC_N PF02463.14 AEO60421.1 - 3.4e-06 26.4 0.0 0.0008 18.7 0.0 2.3 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 AEO60421.1 - 6.9e-05 22.9 0.1 0.00043 20.3 0.0 2.3 3 0 0 3 3 3 1 AAA ATPase domain AAA_21 PF13304.1 AEO60421.1 - 7e-05 22.9 0.0 0.11 12.4 0.0 2.5 1 1 0 2 2 2 2 AAA domain AAA_14 PF13173.1 AEO60421.1 - 0.00081 19.2 0.0 0.0066 16.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 AEO60421.1 - 0.0011 19.0 0.0 0.016 15.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 AEO60421.1 - 0.0012 19.6 0.0 0.0041 17.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 AEO60421.1 - 0.0021 17.2 0.0 0.0051 16.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 AEO60421.1 - 0.0061 16.0 0.1 0.014 14.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 AEO60421.1 - 0.0084 16.0 0.0 0.023 14.6 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_25 PF13481.1 AEO60421.1 - 0.012 15.0 0.0 0.035 13.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 AEO60421.1 - 0.013 14.9 0.0 0.049 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain Miro PF08477.8 AEO60421.1 - 0.017 15.6 0.0 0.044 14.2 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein Arch_ATPase PF01637.13 AEO60421.1 - 0.035 13.7 0.1 0.23 11.1 0.0 2.3 2 1 0 2 2 2 0 Archaeal ATPase DUF87 PF01935.12 AEO60421.1 - 0.035 13.9 0.0 0.073 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA PF00004.24 AEO60421.1 - 0.036 14.2 0.0 0.18 12.0 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 AEO60421.1 - 0.053 13.8 0.0 0.22 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 AEO60421.1 - 0.064 12.3 0.0 0.28 10.2 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin AAA_28 PF13521.1 AEO60421.1 - 0.074 13.0 0.0 0.28 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 AEO60421.1 - 0.078 12.9 0.4 0.63 10.0 0.3 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.7 AEO60421.1 - 0.085 12.5 0.3 0.32 10.6 0.0 2.1 3 0 0 3 3 3 0 NACHT domain Kinesin PF00225.18 AEO60422.1 - 6.2e-82 274.9 0.0 8.5e-82 274.5 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain AIM24 PF01987.12 AEO60423.1 - 9.2e-49 165.8 0.0 1.2e-48 165.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 DUF4402 PF14352.1 AEO60423.1 - 0.14 12.6 0.1 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4402) Chitin_bind_3 PF03067.10 AEO60424.1 - 1.3e-14 54.9 0.4 2.5e-14 53.9 0.3 1.5 1 0 0 1 1 1 1 Chitin binding domain Mucin PF01456.12 AEO60424.1 - 0.012 15.3 20.2 0.024 14.4 14.0 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Herpes_TAF50 PF03326.8 AEO60424.1 - 0.022 13.7 4.7 0.028 13.3 3.2 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) RNA_pol_3_Rpc31 PF11705.3 AEO60424.1 - 0.14 12.1 6.5 0.43 10.4 4.6 1.8 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 SOG2 PF10428.4 AEO60424.1 - 0.51 8.9 3.3 0.62 8.6 2.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Daxx PF03344.10 AEO60424.1 - 5.6 5.3 11.4 7.5 4.8 7.9 1.3 1 0 0 1 1 1 0 Daxx Family MSP1_C PF07462.6 AEO60424.1 - 9.3 4.5 13.3 13 3.9 9.2 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus RVT_1 PF00078.22 AEO60428.1 - 0.0091 15.3 0.2 0.0094 15.3 0.2 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3786 PF12654.2 AEO60428.1 - 0.018 14.3 0.4 0.023 13.9 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3786) Ycf54 PF10674.4 AEO60428.1 - 0.055 13.6 0.1 0.098 12.7 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2488) Peptidase_S15 PF02129.13 AEO60429.1 - 8.6e-40 136.8 0.4 1.1e-39 136.4 0.3 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 AEO60429.1 - 3.7e-33 115.2 0.4 5.8e-33 114.6 0.3 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_5 PF12695.2 AEO60429.1 - 0.00076 19.2 0.2 0.0025 17.5 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSA_C PF10479.4 AEO60429.1 - 0.065 11.2 0.0 0.094 10.7 0.0 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF3117 PF11314.3 AEO60429.1 - 0.12 11.9 0.1 0.24 10.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3117) DUF3439 PF11921.3 AEO60430.1 - 7.2 6.3 9.3 12 5.6 6.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.12 AEO60430.1 - 8.4 6.1 20.1 0.58 9.9 10.6 1.5 2 0 0 2 2 2 0 Mucin-like glycoprotein NUDIX_4 PF14815.1 AEO60431.1 - 8.1e-19 67.1 0.0 1.4e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain HhH-GPD PF00730.20 AEO60431.1 - 2.4e-16 59.9 0.0 4.6e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 AEO60431.1 - 9.7e-06 25.0 0.0 2.8e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.1 AEO60431.1 - 0.0012 18.9 0.5 0.14 12.3 0.0 3.0 3 0 0 3 3 3 1 Helix-hairpin-helix domain EndIII_4Fe-2S PF10576.4 AEO60431.1 - 6.6 7.0 9.2 0.14 12.3 1.4 2.1 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III C2 PF00168.25 AEO60433.1 - 2.8e-14 52.7 0.0 3.2e-11 42.9 0.0 2.4 2 0 0 2 2 2 2 C2 domain DUF2404 PF10296.4 AEO60433.1 - 0.0096 16.0 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) E1-E2_ATPase PF00122.15 AEO60434.1 - 1.4e-58 197.6 0.4 1.4e-58 197.6 0.2 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 AEO60434.1 - 2e-47 161.0 3.0 2e-47 161.0 2.1 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 AEO60434.1 - 7.4e-29 101.6 0.0 8.7e-28 98.2 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AEO60434.1 - 9.7e-20 70.3 0.0 9.6e-19 67.1 0.0 2.4 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 AEO60434.1 - 8.4e-15 55.4 0.0 2e-14 54.2 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 AEO60434.1 - 2.6e-08 33.2 0.2 1.8e-07 30.4 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 AEO60434.1 - 2.6e-07 30.5 0.5 4.6e-05 23.1 0.4 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Nol1_Nop2_Fmu_2 PF13636.1 AEO60435.1 - 0.04 13.9 0.0 5 7.2 0.0 2.4 2 0 0 2 2 2 0 pre-rRNA processing and ribosome biogenesis Nucleoplasmin PF03066.10 AEO60435.1 - 0.39 10.2 7.0 0.7 9.4 4.8 1.4 1 0 0 1 1 1 0 Nucleoplasmin CDC27 PF09507.5 AEO60435.1 - 0.76 8.9 7.6 1.2 8.3 5.3 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Abhydrolase_6 PF12697.2 AEO60436.1 - 1.5e-14 54.4 6.1 2.1e-14 53.9 4.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO60436.1 - 1.8e-10 40.7 0.1 4.7e-10 39.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 AEO60436.1 - 0.00046 20.0 0.0 0.00084 19.1 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Peptidase_S9 PF00326.16 AEO60436.1 - 0.009 15.2 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 AEO60436.1 - 0.021 14.3 0.0 0.45 10.0 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold FSH1 PF03959.8 AEO60437.1 - 5.7e-24 84.7 0.0 9.1e-24 84.0 0.0 1.3 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 AEO60437.1 - 3.2e-05 23.9 0.1 4.7e-05 23.3 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family PE-PPE PF08237.6 AEO60437.1 - 0.1 12.0 0.0 0.24 10.7 0.0 1.5 2 0 0 2 2 2 0 PE-PPE domain ketoacyl-synt PF00109.21 AEO60438.1 - 1.4e-75 254.0 0.0 3e-75 252.9 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 AEO60438.1 - 2.9e-66 223.9 0.0 4.8e-66 223.2 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 AEO60438.1 - 1e-60 204.4 1.3 3e-60 203.0 0.9 1.9 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 AEO60438.1 - 7.4e-49 165.8 1.3 2.5e-48 164.1 0.9 2.0 1 0 0 1 1 1 1 short chain dehydrogenase PS-DH PF14765.1 AEO60438.1 - 1.7e-35 122.6 0.0 4.2e-21 75.3 0.0 2.5 1 1 1 2 2 2 2 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 AEO60438.1 - 3e-34 117.3 0.0 2.2e-33 114.6 0.0 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 AEO60438.1 - 8.8e-12 44.7 0.0 1.5e-10 40.7 0.0 3.1 4 0 0 4 4 4 1 Zinc-binding dehydrogenase PP-binding PF00550.20 AEO60438.1 - 2e-10 40.7 0.4 4.8e-10 39.5 0.3 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 AEO60438.1 - 3.5e-06 26.1 0.0 0.00011 21.2 0.0 2.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Epimerase PF01370.16 AEO60438.1 - 8.1e-06 25.4 0.1 1.7e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 AEO60438.1 - 8.8e-06 24.8 0.0 1.5e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 AEO60438.1 - 0.0013 18.0 0.1 0.0027 17.0 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 AEO60438.1 - 0.0044 17.0 1.5 0.025 14.5 0.2 2.8 3 0 0 3 3 3 1 NADH(P)-binding 3Beta_HSD PF01073.14 AEO60438.1 - 0.0049 15.6 0.2 0.0079 14.9 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.15 AEO60438.1 - 0.065 13.3 0.1 0.17 11.9 0.1 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ACP_syn_III PF08545.5 AEO60438.1 - 0.13 11.9 3.0 0.25 11.0 0.2 3.1 3 1 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Fer4 PF00037.22 AEO60440.1 - 1.4e-13 49.8 16.5 5.3e-08 32.1 2.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 AEO60440.1 - 7.3e-12 45.4 10.6 1.1e-11 44.8 7.3 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 AEO60440.1 - 6e-10 39.2 8.3 1.1e-09 38.3 5.8 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 AEO60440.1 - 1.1e-09 38.8 7.2 0.00022 21.9 0.3 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.1 AEO60440.1 - 2e-09 37.0 21.9 7e-08 32.1 8.4 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.1 AEO60440.1 - 8.6e-09 35.1 32.3 1.1e-05 25.1 8.7 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.2 AEO60440.1 - 1e-07 31.4 14.7 0.00043 20.0 1.6 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.1 AEO60440.1 - 2.1e-07 30.8 21.2 2.8e-05 24.0 8.3 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.2 AEO60440.1 - 2.2e-07 30.4 17.1 0.0012 18.6 3.6 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 AEO60440.1 - 5.2e-06 26.3 12.7 0.00057 19.9 2.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 AEO60440.1 - 1.2e-05 25.5 10.4 0.0011 19.3 7.9 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_18 PF13746.1 AEO60440.1 - 4.8e-05 23.7 9.5 0.014 15.8 0.5 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 AEO60440.1 - 0.0077 16.5 15.0 0.3 11.5 3.2 2.7 2 1 1 3 3 3 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 AEO60440.1 - 0.011 16.3 12.8 0.21 12.1 1.1 2.8 2 1 0 2 2 2 0 4Fe-4S single cluster domain Fer4_3 PF12798.2 AEO60440.1 - 0.07 13.7 16.9 0.16 12.6 2.4 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 AEO60440.1 - 0.11 12.5 4.8 0.26 11.4 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain PP-binding PF00550.20 AEO60441.1 - 4.1e-12 46.1 0.2 5.8e-12 45.6 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 AEO60441.1 - 1.1e-05 25.3 0.1 1.5e-05 24.9 0.1 1.2 1 0 0 1 1 1 1 Acyl-carrier zf-CCCH PF00642.19 AEO60442.1 - 1.9e-10 40.1 7.9 3.4e-05 23.4 1.4 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 AEO60442.1 - 0.56 10.2 16.3 0.23 11.5 3.4 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Glyco_trans_2_3 PF13632.1 AEO60443.1 - 3.7e-11 43.1 1.7 3.7e-11 43.1 1.2 1.7 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 AEO60443.1 - 7.3e-11 42.3 0.1 8.4e-10 38.8 0.1 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 AEO60443.1 - 3e-10 39.6 0.1 7e-10 38.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.10 AEO60443.1 - 5.2e-07 28.4 0.3 2.5e-05 22.8 0.2 2.3 1 1 0 1 1 1 1 Chitin synthase Fringe PF02434.11 AEO60444.1 - 2.5e-06 26.8 0.5 3.5e-05 23.1 0.4 2.3 1 1 0 1 1 1 1 Fringe-like PAN_4 PF14295.1 AEO60444.1 - 0.0028 17.3 3.4 0.0078 15.8 2.4 1.7 1 0 0 1 1 1 1 PAN domain BNR_2 PF13088.1 AEO60445.1 - 0.00074 18.8 0.2 0.02 14.1 0.1 2.3 1 1 1 2 2 2 2 BNR repeat-like domain BNR PF02012.15 AEO60445.1 - 0.043 13.6 6.1 0.98 9.5 0.1 3.7 3 0 0 3 3 3 0 BNR/Asp-box repeat Cupin_1 PF00190.17 AEO60446.1 - 3.1e-24 85.0 0.0 3.8e-12 45.8 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 AEO60446.1 - 1.4e-17 62.9 0.1 1e-08 34.5 0.1 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 AEO60446.1 - 3.9e-06 26.1 0.0 0.014 14.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_6 PF12852.2 AEO60446.1 - 0.057 13.0 0.0 0.18 11.3 0.0 1.8 2 0 0 2 2 2 0 Cupin p450 PF00067.17 AEO60447.1 - 1.3e-52 178.9 0.0 1.6e-52 178.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 He_PIG PF05345.7 AEO60448.1 - 0.07 13.1 2.1 0.18 11.8 1.1 2.0 2 1 0 2 2 2 0 Putative Ig domain STAS_2 PF13466.1 AEO60448.1 - 0.15 12.1 0.6 1.2 9.2 0.1 2.1 2 0 0 2 2 2 0 STAS domain Sugar_tr PF00083.19 AEO60449.1 - 4.8e-72 242.9 19.9 5.5e-72 242.7 13.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO60449.1 - 3.5e-23 81.9 26.5 3.5e-23 81.9 18.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2301 PF10063.4 AEO60449.1 - 9.6 6.4 12.7 0.17 12.0 1.3 3.0 3 0 0 3 3 3 0 Uncharacterized integral membrane protein (DUF2301) AMP-binding PF00501.23 AEO60450.1 - 7e-33 113.6 0.0 2.3e-32 111.9 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.7 AEO60450.1 - 5.3e-32 110.7 0.0 7.8e-32 110.1 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 AEO60450.1 - 2.4e-11 43.5 0.0 6.6e-11 42.0 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 AEO60450.1 - 4.5e-06 26.8 0.0 1e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 AEO60450.1 - 0.0093 15.8 0.0 0.027 14.4 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase DUF3356 PF11836.3 AEO60450.1 - 0.083 12.6 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3356) DUF423 PF04241.10 AEO60452.1 - 4.7e-24 84.1 0.7 9.1e-24 83.2 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF423) DUF3325 PF11804.3 AEO60452.1 - 4.4 7.2 9.7 43 4.0 6.8 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3325) DUF2196 PF09962.4 AEO60453.1 - 2.3e-24 84.9 0.7 3.2e-24 84.4 0.5 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) p450 PF00067.17 AEO60455.1 - 9e-52 176.1 0.0 1.1e-51 175.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.13 AEO60456.1 - 3.2e-09 36.5 8.7 5.9e-09 35.7 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 AEO60456.1 - 1.2e-08 34.0 1.5 1.5e-08 33.6 1.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_10 PF00331.15 AEO60457.1 - 2.3e-101 339.0 0.0 2.7e-101 338.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.13 AEO60457.1 - 1.1e-15 56.9 10.2 2.8e-15 55.6 7.1 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Herpes_capsid PF06112.6 AEO60457.1 - 1.8 8.5 8.4 4.3 7.3 5.9 1.6 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Peptidase_M28 PF04389.12 AEO60458.1 - 1.8e-36 125.5 0.1 3.7e-36 124.5 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.17 AEO60458.1 - 6.3e-12 45.0 0.0 9.5e-11 41.2 0.0 2.5 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.23 AEO60458.1 - 4.7e-06 26.2 0.0 7.4e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 ChiC PF06483.6 AEO60459.1 - 0.12 12.1 0.6 0.19 11.4 0.4 1.3 1 0 0 1 1 1 0 Chitinase C Miff PF05644.6 AEO60459.1 - 0.42 10.1 3.4 0.76 9.3 2.3 1.4 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff U79_P34 PF03064.11 AEO60459.1 - 0.88 9.0 6.9 1.9 7.9 4.8 1.5 1 1 0 1 1 1 0 HSV U79 / HCMV P34 eIF-3c_N PF05470.7 AEO60459.1 - 8.8 4.2 7.2 12 3.8 5.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Cutinase PF01083.17 AEO60460.1 - 4.2e-52 176.4 9.3 6e-52 175.9 6.4 1.2 1 0 0 1 1 1 1 Cutinase CBM_1 PF00734.13 AEO60460.1 - 1.9e-09 37.0 16.4 1.9e-09 37.0 11.4 4.0 4 1 0 4 4 4 1 Fungal cellulose binding domain PE-PPE PF08237.6 AEO60460.1 - 1.6e-05 24.4 0.1 3.1e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_6 PF12697.2 AEO60460.1 - 0.00029 20.8 0.0 0.00062 19.7 0.0 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO60460.1 - 0.0078 15.7 0.0 0.027 14.0 0.0 1.6 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AEO60460.1 - 0.011 15.4 0.2 0.035 13.8 0.1 1.8 1 1 1 2 2 2 0 Alpha/beta hydrolase family VirJ PF06057.6 AEO60460.1 - 0.16 11.7 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Toxin_7 PF05980.7 AEO60460.1 - 6.5 6.8 23.5 0.11 12.5 6.3 3.5 3 1 0 3 3 3 0 Toxin 7 MFS_1 PF07690.11 AEO60461.1 - 4.2e-10 38.8 57.6 2.4e-08 33.1 14.4 3.3 1 1 1 3 3 3 2 Major Facilitator Superfamily OATP PF03137.15 AEO60461.1 - 5.4e-05 21.4 1.1 0.00015 19.9 0.8 1.8 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family XFP_N PF09364.5 AEO60462.1 - 1.6e-148 494.3 0.0 2.1e-148 493.9 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.5 AEO60462.1 - 3.4e-67 225.8 0.0 5.6e-67 225.1 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.10 AEO60462.1 - 7.6e-64 214.5 0.1 6.9e-58 195.1 0.0 2.2 1 1 1 2 2 2 2 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase TPP_enzyme_C PF02775.16 AEO60462.1 - 0.00068 19.2 0.1 0.0049 16.4 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Lactamase_B_3 PF13483.1 AEO60462.1 - 0.12 12.1 0.1 0.68 9.6 0.0 2.3 2 0 0 2 2 2 0 Beta-lactamase superfamily domain Transket_pyr PF02779.19 AEO60462.1 - 0.15 11.5 0.0 0.31 10.4 0.0 1.5 1 0 0 1 1 1 0 Transketolase, pyrimidine binding domain Hexapep PF00132.19 AEO60463.1 - 4.8e-15 54.2 18.5 2.2e-11 42.6 4.0 2.7 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 AEO60463.1 - 4.2e-10 39.0 20.5 4.7e-08 32.4 3.5 2.8 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase LigB PF02900.13 AEO60463.1 - 0.024 13.6 0.0 0.039 12.9 0.0 1.2 1 0 0 1 1 1 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase Mac PF12464.3 AEO60463.1 - 0.24 11.4 2.9 0.27 11.2 0.0 2.2 2 0 0 2 2 2 0 Maltose acetyltransferase DUF463 PF04317.7 AEO60464.1 - 0.00083 18.0 0.0 0.0011 17.6 0.0 1.1 1 0 0 1 1 1 1 YcjX-like family, DUF463 RseA_C PF03873.8 AEO60464.1 - 0.046 13.5 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Anti sigma-E protein RseA, C-terminal domain PhoPQ_related PF10142.4 AEO60464.1 - 0.14 10.5 0.0 0.2 10.0 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein AXE1 PF05448.7 AEO60465.1 - 0.055 11.9 0.0 0.085 11.3 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) F-box-like PF12937.2 AEO60466.1 - 0.0063 16.2 1.5 0.016 14.9 1.1 1.7 1 0 0 1 1 1 1 F-box-like FAD_binding_4 PF01565.18 AEO60468.1 - 2e-18 66.2 0.3 4e-18 65.2 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 AEO60468.1 - 9.9e-07 28.5 0.1 2.5e-06 27.3 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like DUF1338 PF07063.8 AEO60470.1 - 2.3e-81 273.1 0.0 2.7e-81 272.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) V-SNARE_C PF12352.3 AEO60471.1 - 0.048 13.7 0.4 0.084 12.9 0.3 1.5 1 1 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus Zn_clus PF00172.13 AEO60471.1 - 1.8 8.5 10.4 7.3 6.6 3.2 2.2 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.7 AEO60472.1 - 1.8e-11 43.7 0.0 2.3e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain FSH1 PF03959.8 AEO60472.1 - 0.1 12.0 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Cupin_2 PF07883.6 AEO60473.1 - 1.7e-08 33.8 0.7 3.9e-05 23.0 0.4 3.3 2 1 0 2 2 2 2 Cupin domain AAA_16 PF13191.1 AEO60474.1 - 3.1e-06 27.3 0.0 3.1e-06 27.3 0.0 5.4 5 0 0 5 5 5 1 AAA ATPase domain TPR_7 PF13176.1 AEO60474.1 - 9.9e-06 24.9 7.2 3.3 7.7 0.0 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_10 PF13374.1 AEO60474.1 - 0.00018 21.3 10.4 20 5.2 0.0 7.9 8 0 0 8 8 8 1 Tetratricopeptide repeat AAA_19 PF13245.1 AEO60474.1 - 0.0045 16.6 0.0 0.018 14.7 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 AEO60474.1 - 0.0073 16.4 0.8 0.3 11.2 0.0 3.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 AEO60474.1 - 0.011 16.5 0.0 0.076 13.8 0.0 2.6 1 0 0 1 1 1 0 AAA domain TPR_12 PF13424.1 AEO60474.1 - 0.66 9.9 25.9 0.78 9.7 0.0 8.3 11 0 0 11 11 11 0 Tetratricopeptide repeat HNH_2 PF13391.1 AEO60475.1 - 2.3e-10 40.0 0.0 6.3e-10 38.6 0.0 1.8 1 0 0 1 1 1 1 HNH endonuclease GST_N_3 PF13417.1 AEO60476.1 - 2.2e-05 24.6 0.0 4e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 AEO60476.1 - 6.1e-05 22.9 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glyco_hydro_3 PF00933.16 AEO60477.1 - 2.9e-68 230.0 0.0 3.9e-68 229.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 AEO60477.1 - 6.5e-63 212.2 0.1 1.1e-62 211.5 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 AEO60477.1 - 8e-24 83.3 2.5 2e-23 82.0 0.1 2.6 2 0 0 2 2 2 1 Fibronectin type III-like domain DUF11 PF01345.13 AEO60477.1 - 0.004 17.1 4.1 0.016 15.2 2.8 2.0 1 0 0 1 1 1 1 Domain of unknown function DUF11 CARDB PF07705.6 AEO60477.1 - 0.034 14.1 0.0 0.21 11.6 0.1 2.2 2 0 0 2 2 2 0 CARDB Sugar-bind PF04198.8 AEO60477.1 - 0.07 12.0 0.1 0.15 10.9 0.0 1.5 1 0 0 1 1 1 0 Putative sugar-binding domain Glyco_hydro_31 PF01055.21 AEO60478.1 - 1.3e-110 370.2 0.0 1.6e-110 369.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 AEO60478.1 - 1.3e-17 63.3 0.4 5.3e-17 61.4 0.0 2.2 3 0 0 3 3 3 1 Galactose mutarotase-like Sugar_tr PF00083.19 AEO60479.1 - 3.2e-100 335.8 23.2 3.6e-100 335.6 16.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO60479.1 - 1.7e-28 99.3 46.9 7e-27 94.0 18.8 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 AEO60479.1 - 3.7e-05 22.1 1.0 3.7e-05 22.1 0.7 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF791 PF05631.9 AEO60479.1 - 0.0002 20.2 0.7 0.0002 20.2 0.5 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF791) UPF0060 PF02694.10 AEO60479.1 - 0.015 15.2 2.9 0.048 13.6 0.1 2.8 2 1 0 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family p450 PF00067.17 AEO60480.1 - 1e-59 202.3 0.0 6.3e-59 199.6 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 DUF2884 PF11101.3 AEO60481.1 - 0.078 12.3 0.0 12 5.1 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2884) Rtt106 PF08512.7 AEO60482.1 - 2.1e-23 82.1 0.0 5.8e-23 80.7 0.0 1.8 2 0 0 2 2 2 1 Histone chaperone Rttp106-like HemY_N PF07219.8 AEO60483.1 - 0.031 13.8 0.3 0.037 13.5 0.2 1.1 1 0 0 1 1 1 0 HemY protein N-terminus VirB3 PF05101.8 AEO60483.1 - 0.071 13.0 0.6 0.093 12.7 0.4 1.2 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein DUF4131 PF13567.1 AEO60483.1 - 0.17 11.3 1.1 0.19 11.1 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) SIT PF15330.1 AEO60483.1 - 0.66 10.1 2.5 0.88 9.7 1.7 1.3 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT zf-C2H2_4 PF13894.1 AEO60484.1 - 1e-05 25.4 17.6 0.09 13.1 0.5 4.8 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 AEO60484.1 - 0.00038 20.6 22.5 0.075 13.3 0.6 4.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-CHCC PF10276.4 AEO60484.1 - 0.46 10.3 3.9 3.2 7.6 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger domain zf-C2H2_jaz PF12171.3 AEO60484.1 - 2.6 8.3 10.7 3.1 8.0 1.1 3.3 2 1 1 3 3 3 0 Zinc-finger double-stranded RNA-binding DSPc PF00782.15 AEO60485.1 - 1.7e-19 69.7 0.2 2e-10 40.3 0.3 3.2 2 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 AEO60485.1 - 0.0042 17.1 0.0 0.0077 16.2 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.22 AEO60485.1 - 0.06 12.6 0.0 0.094 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 AEO60485.1 - 0.091 11.6 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase DHHA1 PF02272.14 AEO60485.1 - 0.7 9.6 3.6 1.6 8.5 2.5 1.5 1 0 0 1 1 1 0 DHHA1 domain Vfa1 PF08432.5 AEO60486.1 - 1.2e-56 191.6 18.9 1.4e-56 191.4 13.1 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 DUF4407 PF14362.1 AEO60486.1 - 0.023 13.6 7.3 0.028 13.3 5.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Astro_capsid PF03115.9 AEO60486.1 - 0.031 12.5 5.2 0.038 12.2 3.6 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Ycf1 PF05758.7 AEO60486.1 - 0.042 11.5 12.3 0.049 11.3 8.5 1.0 1 0 0 1 1 1 0 Ycf1 BTV_NS2 PF04514.7 AEO60486.1 - 0.14 11.0 9.6 0.17 10.7 6.7 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Borrelia_P83 PF05262.6 AEO60486.1 - 0.49 8.5 16.5 0.57 8.3 11.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Hid1 PF12722.2 AEO60486.1 - 1.1 6.7 8.4 1.3 6.6 5.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1510 PF07423.6 AEO60486.1 - 1.2 8.4 20.5 1.5 8.0 14.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF3987 PF13148.1 AEO60486.1 - 1.2 7.6 16.6 1.6 7.2 11.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF2201_N PF13203.1 AEO60486.1 - 2.2 7.3 8.3 2.6 7.1 5.8 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Iron_permease PF04120.7 AEO60486.1 - 2.5 7.6 5.1 5.6 6.5 3.6 1.5 1 0 0 1 1 1 0 Low affinity iron permease CDC45 PF02724.9 AEO60486.1 - 2.9 5.8 19.7 3.4 5.5 13.7 1.0 1 0 0 1 1 1 0 CDC45-like protein Sporozoite_P67 PF05642.6 AEO60486.1 - 4.8 4.9 10.8 5.8 4.6 7.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MIP-T3 PF10243.4 AEO60486.1 - 5.3 5.4 28.8 6.5 5.1 20.0 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 U79_P34 PF03064.11 AEO60486.1 - 6.5 6.1 17.4 9.2 5.6 12.0 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 RP-C_C PF11800.3 AEO60486.1 - 8.1 6.0 9.2 10 5.7 6.4 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region FAD_binding_3 PF01494.14 AEO60487.1 - 1.1e-14 54.2 0.2 2.2e-13 50.0 0.1 2.6 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 AEO60487.1 - 0.00035 19.5 0.1 0.15 10.9 0.0 2.7 3 0 0 3 3 3 2 Lycopene cyclase protein DAO PF01266.19 AEO60487.1 - 0.00058 18.8 0.0 0.34 9.7 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AEO60487.1 - 0.0014 18.6 0.0 0.0032 17.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 AEO60487.1 - 0.022 14.6 0.1 1.5 8.6 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AEO60487.1 - 0.12 12.3 0.1 4.6 7.2 0.0 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase zf-C2H2 PF00096.21 AEO60488.1 - 0.08 13.3 0.0 0.22 11.9 0.0 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type SET PF00856.23 AEO60489.1 - 1.7e-07 31.6 0.0 3.1e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 SET domain TPR_12 PF13424.1 AEO60489.1 - 0.0053 16.6 0.0 0.014 15.2 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat GDPD PF03009.12 AEO60490.1 - 4e-16 59.3 0.0 6.2e-16 58.6 0.0 1.4 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF3761 PF12587.3 AEO60491.1 - 0.042 13.9 0.0 0.072 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3761) Pyridox_oxidase PF01243.15 AEO60492.1 - 9.3e-06 25.5 0.0 1.7e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase adh_short PF00106.20 AEO60493.1 - 3.1e-16 59.7 2.2 4.5e-16 59.2 1.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO60493.1 - 2.9e-05 23.8 1.2 3.6e-05 23.4 0.8 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 AEO60493.1 - 5e-05 23.1 0.0 6.1e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF2263 PF10021.4 AEO60494.1 - 9.9e-21 74.2 0.1 3e-20 72.7 0.0 1.7 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) APH PF01636.18 AEO60495.1 - 3.3e-31 108.8 2.5 7.2e-31 107.7 1.7 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Abhydrolase_3 PF07859.8 AEO60496.1 - 2.8e-51 174.0 0.1 3.6e-51 173.7 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AEO60496.1 - 0.00035 20.3 0.0 0.00054 19.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 AEO60496.1 - 0.022 14.0 3.4 0.088 12.0 0.7 2.5 2 1 0 2 2 2 0 Esterase PHB depolymerase Pkinase PF00069.20 AEO60498.1 - 4.9e-18 65.2 0.0 6.2e-18 64.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 AEO60498.1 - 3.5e-09 36.0 0.0 4.8e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.12 AEO60498.1 - 2.8e-08 33.1 0.0 3.1e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 AEO60498.1 - 0.00038 19.5 0.0 0.00061 18.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 AEO60498.1 - 0.0074 15.6 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 AEO60498.1 - 0.0085 15.8 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 AEO60498.1 - 0.042 12.6 0.2 0.066 12.0 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 EcKinase PF02958.15 AEO60498.1 - 0.19 10.8 0.0 0.26 10.3 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase APH PF01636.18 AEO60499.1 - 1.2e-15 57.9 0.2 2.6e-15 56.8 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 AEO60499.1 - 0.018 14.6 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF2781 PF10914.3 AEO60500.1 - 5.5e-37 126.8 6.3 6.4e-37 126.6 4.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) PLDc_N PF13396.1 AEO60503.1 - 3.5e-13 48.9 5.0 5.2e-13 48.4 3.5 1.3 1 0 0 1 1 1 1 Phospholipase_D-nuclease N-terminal Pox_A14 PF05767.7 AEO60503.1 - 0.02 14.8 0.2 0.029 14.3 0.1 1.3 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 DUF4293 PF14126.1 AEO60503.1 - 0.074 12.9 0.4 0.099 12.5 0.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) DUF3951 PF13131.1 AEO60503.1 - 0.079 12.7 3.4 0.63 9.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3951) NfeD PF01957.13 AEO60503.1 - 0.085 12.9 1.3 0.089 12.9 0.6 1.3 1 1 0 1 1 1 0 NfeD-like C-terminal, partner-binding Glucos_trans_II PF14264.1 AEO60503.1 - 0.1 11.5 5.1 0.13 11.2 3.5 1.3 1 1 0 1 1 1 0 Glucosyl transferase GtrII DUF3671 PF12420.3 AEO60503.1 - 0.1 12.5 0.9 1.5 8.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF4149 PF13664.1 AEO60503.1 - 0.13 12.2 1.0 0.17 11.9 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) Cation_ATPase_C PF00689.16 AEO60503.1 - 0.18 11.2 4.2 0.28 10.7 2.9 1.3 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus Tic20 PF09685.5 AEO60503.1 - 0.31 11.0 3.1 1.7 8.6 0.0 2.1 1 1 1 2 2 2 0 Tic20-like protein ABC2_membrane_4 PF12730.2 AEO60503.1 - 2.1 7.4 8.2 0.21 10.7 0.3 2.0 1 1 1 2 2 2 0 ABC-2 family transporter protein DUF21 PF01595.15 AEO60503.1 - 2.6 7.2 7.4 5.1 6.3 5.1 1.6 1 1 0 1 1 1 0 Domain of unknown function DUF21 TauD PF02668.11 AEO60505.1 - 4.5e-31 108.4 0.3 5.8e-31 108.0 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 AEO60505.1 - 0.07 12.0 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 CsiD AA_permease_2 PF13520.1 AEO60506.1 - 3.5e-73 246.5 30.9 4.3e-73 246.2 21.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 AEO60506.1 - 3.2e-11 42.2 28.4 5.5e-11 41.4 19.7 1.3 1 1 0 1 1 1 1 Amino acid permease CEP170_C PF15308.1 AEO60508.1 - 0.11 10.7 6.9 0.12 10.6 4.8 1.1 1 0 0 1 1 1 0 CEP170 C-terminus Kinesin PF00225.18 AEO60509.1 - 1.2e-54 185.2 0.0 3.2e-54 183.8 0.0 1.7 1 1 0 1 1 1 1 Kinesin motor domain HALZ PF02183.13 AEO60509.1 - 0.0063 16.2 1.5 0.007 16.0 0.1 1.8 2 0 0 2 2 2 1 Homeobox associated leucine zipper RIX1 PF08167.7 AEO60509.1 - 0.009 15.6 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis DUF1640 PF07798.6 AEO60509.1 - 0.0096 15.9 0.2 0.029 14.4 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1640) Kinetocho_Slk19 PF12709.2 AEO60509.1 - 0.097 12.7 3.5 1.4 9.0 0.4 2.4 2 0 0 2 2 2 0 Central kinetochore-associated DUF87 PF01935.12 AEO60509.1 - 0.15 11.8 1.6 5.9 6.6 0.4 2.9 2 1 0 2 2 2 0 Domain of unknown function DUF87 Herpes_BLRF2 PF05812.7 AEO60509.1 - 0.43 10.4 6.7 1.6 8.5 0.2 2.5 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein DivIC PF04977.10 AEO60509.1 - 0.53 9.8 6.1 2.5 7.6 0.1 2.5 2 0 0 2 2 2 0 Septum formation initiator DivIVA PF05103.8 AEO60509.1 - 0.87 9.6 5.5 11 6.0 0.0 2.5 2 0 0 2 2 2 0 DivIVA protein Jnk-SapK_ap_N PF09744.4 AEO60509.1 - 1.8 8.5 8.2 0.14 12.1 2.0 1.8 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 IncA PF04156.9 AEO60509.1 - 9.8 5.7 8.0 6.6 6.2 1.8 2.4 2 0 0 2 2 2 0 IncA protein ApbA_C PF08546.6 AEO60511.1 - 1.1e-35 122.3 0.0 1.7e-35 121.7 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 AEO60511.1 - 4.7e-26 91.0 0.0 1.9e-25 89.0 0.0 1.9 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 AEO60511.1 - 0.019 14.7 0.0 0.42 10.3 0.0 2.4 3 0 0 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ABC_tran PF00005.22 AEO60512.1 - 6.8e-24 84.7 0.0 9.5e-10 38.9 0.0 4.0 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 AEO60512.1 - 7.4e-09 35.9 0.0 0.016 15.1 0.0 3.6 4 0 0 4 4 4 2 AAA domain AAA_17 PF13207.1 AEO60512.1 - 4.8e-07 30.6 0.0 0.05 14.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 AEO60512.1 - 8e-07 28.9 0.0 0.0024 17.7 0.0 2.4 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 AEO60512.1 - 2.6e-05 23.6 0.0 0.048 13.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 AEO60512.1 - 0.00024 21.4 0.1 0.073 13.3 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 AEO60512.1 - 0.001 18.5 0.0 1.2 8.4 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 AEO60512.1 - 0.0011 19.0 0.1 1.8 8.6 0.0 3.3 4 0 0 4 4 3 1 AAA domain AAA_10 PF12846.2 AEO60512.1 - 0.0043 16.5 0.0 1.4 8.3 0.0 2.4 2 0 0 2 2 2 1 AAA-like domain AAA_33 PF13671.1 AEO60512.1 - 0.0057 16.5 0.1 2.8 7.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 AEO60512.1 - 0.013 15.4 0.1 4.5 7.2 0.1 2.9 2 1 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 AEO60512.1 - 0.015 15.2 0.0 5.5 6.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 AEO60512.1 - 0.017 15.5 0.0 2 8.9 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein AAA_18 PF13238.1 AEO60512.1 - 0.022 15.0 0.0 7.3 6.9 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_28 PF13521.1 AEO60512.1 - 0.037 13.9 0.1 11 5.9 0.0 3.2 4 0 0 4 4 3 0 AAA domain FtsK_SpoIIIE PF01580.13 AEO60512.1 - 0.041 13.3 0.0 3.5 7.0 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family PduV-EutP PF10662.4 AEO60512.1 - 0.047 13.1 0.0 0.47 9.9 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 AEO60512.1 - 0.048 13.3 0.1 12 5.6 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 AEO60512.1 - 0.064 13.4 0.0 2.5 8.3 0.0 2.4 2 0 0 2 2 2 0 RNA helicase ATP_bind_1 PF03029.12 AEO60512.1 - 0.1 12.1 0.1 3.1 7.2 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF258 PF03193.11 AEO60512.1 - 0.11 11.6 0.0 17 4.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA PF00004.24 AEO60512.1 - 0.13 12.4 0.1 0.81 9.8 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 AEO60512.1 - 0.18 11.3 0.0 7.5 6.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.1 AEO60512.1 - 0.36 9.2 0.0 0.57 8.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.1 AEO60512.1 - 0.42 9.6 0.0 4.5 6.2 0.0 2.2 3 0 0 3 3 3 0 AAA ATPase domain UMP1 PF05348.6 AEO60513.1 - 1.6e-23 83.0 0.0 2e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Rad60-SLD_2 PF13881.1 AEO60514.1 - 5.1e-13 48.8 0.0 1.1e-12 47.8 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 AEO60514.1 - 1.5e-06 27.4 0.0 2.6e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 AEO60514.1 - 0.00013 22.0 0.4 0.00029 20.9 0.0 1.7 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain PetM PF08041.6 AEO60515.1 - 0.5 9.8 3.3 1.5 8.3 2.3 1.9 1 0 0 1 1 1 0 PetM family of cytochrome b6f complex subunit 7 DUF515 PF04415.7 AEO60515.1 - 3.2 5.9 14.4 4.4 5.4 10.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Neuregulin PF02158.10 AEO60515.1 - 6.1 5.5 16.5 7.4 5.2 11.5 1.2 1 0 0 1 1 1 0 Neuregulin family Adaptin_N PF01602.15 AEO60516.1 - 9.4e-136 453.1 5.4 1.3e-135 452.7 3.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 AEO60516.1 - 8.4e-18 64.4 3.2 3.4e-11 43.2 0.1 4.7 3 1 1 4 4 4 2 HEAT repeats Cnd1 PF12717.2 AEO60516.1 - 1.7e-17 63.8 1.9 3.4e-17 62.8 0.0 2.4 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 AEO60516.1 - 5.3e-13 47.8 1.6 0.00035 20.3 0.0 5.2 5 0 0 5 5 4 3 HEAT repeat HEAT_EZ PF13513.1 AEO60516.1 - 2.4e-05 24.6 2.9 1.1 9.8 0.0 6.1 5 1 1 6 6 6 1 HEAT-like repeat CLASP_N PF12348.3 AEO60516.1 - 0.00017 21.0 1.8 0.14 11.4 0.0 3.2 3 1 0 3 3 3 2 CLASP N terminal Arm PF00514.18 AEO60516.1 - 0.0022 17.7 1.8 3.9 7.4 0.0 4.9 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.4 AEO60516.1 - 0.0031 17.2 0.0 0.36 10.5 0.0 3.7 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain DUF2435 PF10363.4 AEO60516.1 - 0.0079 16.0 0.8 0.22 11.4 0.0 3.4 3 1 1 4 4 4 1 Protein of unknown function (DUF2435) Suf PF05843.9 AEO60516.1 - 0.019 14.6 4.5 0.037 13.7 3.1 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FimP PF09766.4 AEO60516.1 - 0.17 10.9 12.0 0.3 10.1 8.3 1.3 1 0 0 1 1 1 0 Fms-interacting protein ERK-JNK_inhib PF15002.1 AEO60516.1 - 1.7 7.9 10.6 0.92 8.8 5.2 2.0 2 0 0 2 2 2 0 ERK and JNK pathways, inhibitor DUF4557 PF15101.1 AEO60516.1 - 5.8 6.6 12.5 12 5.6 8.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF4175 PF13779.1 AEO60516.1 - 6.4 4.3 26.9 9.6 3.7 18.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF1077 PF06417.7 AEO60517.1 - 1.8e-54 182.3 4.1 2.3e-54 182.0 2.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) MARVEL PF01284.18 AEO60518.1 - 0.0056 16.5 0.0 0.46 10.2 0.0 2.1 2 0 0 2 2 2 2 Membrane-associating domain Chitin_synth_1 PF01644.12 AEO60519.1 - 7.9e-86 285.8 0.3 1.2e-85 285.3 0.2 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 AEO60519.1 - 4.4e-33 112.8 0.1 8.8e-33 111.8 0.1 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 AEO60519.1 - 2.8e-24 85.4 2.9 1.4e-21 76.5 0.0 2.3 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 AEO60519.1 - 1.2e-09 38.1 0.4 1.2e-09 38.1 0.3 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 AEO60519.1 - 2.4e-06 27.4 0.0 4.8e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 NIR_SIR PF01077.17 AEO60520.1 - 6.5e-55 184.7 0.0 2.8e-48 163.2 0.0 2.5 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 AEO60520.1 - 1.4e-32 111.0 0.0 1.7e-16 59.5 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 AEO60520.1 - 8.6e-31 106.8 0.0 1.9e-30 105.7 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.14 AEO60520.1 - 6.3e-08 32.3 0.0 2.8e-07 30.2 0.0 1.9 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Kei1 PF08552.6 AEO60521.1 - 1.1e-51 175.2 2.1 1.3e-51 175.0 1.5 1.0 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 DUF2417 PF10329.4 AEO60521.1 - 0.0024 17.3 0.0 0.0035 16.7 0.0 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Ribosomal_L24e PF01246.15 AEO60523.1 - 2.5e-27 94.5 3.8 6.6e-27 93.1 2.6 1.7 1 0 0 1 1 1 1 Ribosomal protein L24e SpoU_sub_bind PF08032.7 AEO60523.1 - 0.14 12.3 0.3 0.34 11.0 0.2 1.8 1 1 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding Ras PF00071.17 AEO60524.1 - 1.4e-59 200.0 0.3 1.9e-59 199.6 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AEO60524.1 - 4.8e-21 75.4 0.0 8.1e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AEO60524.1 - 7.6e-18 64.3 0.2 9.3e-18 64.0 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 AEO60524.1 - 2e-08 33.8 0.0 8.9e-08 31.7 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 AEO60524.1 - 1.9e-06 27.2 0.3 2.3e-06 26.9 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 AEO60524.1 - 9.3e-06 24.9 0.0 1.5e-05 24.3 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 AEO60524.1 - 9.5e-06 25.5 0.0 1.5e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 AEO60524.1 - 0.01 15.4 0.1 0.033 13.7 0.0 1.7 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.1 AEO60524.1 - 0.023 14.6 0.1 1.6 8.6 0.0 2.2 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 AEO60524.1 - 0.025 14.3 0.1 3 7.6 0.0 2.5 2 1 0 2 2 2 0 Dynamin family AAA_14 PF13173.1 AEO60524.1 - 0.067 13.0 0.3 0.13 12.1 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 AEO60524.1 - 0.11 12.6 0.0 1.1 9.4 0.0 2.4 1 1 0 1 1 1 0 AAA domain Glyco_hydro_3_C PF01915.17 AEO60524.1 - 0.14 11.6 0.7 0.34 10.3 0.4 1.3 1 1 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain Nop53 PF07767.6 AEO60525.1 - 8.8e-109 364.0 35.0 1e-108 363.7 24.3 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) DUF4002 PF13164.1 AEO60527.1 - 0.48 10.4 4.3 0.74 9.8 2.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4002) Sugar_tr PF00083.19 AEO60528.1 - 4.4e-75 252.9 24.8 5e-75 252.7 17.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO60528.1 - 2.6e-15 55.9 32.6 2.6e-15 55.9 22.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Pyr_redox_2 PF07992.9 AEO60530.1 - 4.2e-25 88.8 0.0 5.8e-25 88.3 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AEO60530.1 - 5.8e-16 58.6 0.0 2.5e-11 43.8 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 AEO60530.1 - 9.3e-07 27.7 0.1 3.5e-06 25.9 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 AEO60530.1 - 2.3e-05 23.8 0.2 9.3e-05 22.0 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 AEO60530.1 - 6.6e-05 22.9 1.0 0.00014 21.9 0.1 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 AEO60530.1 - 0.00075 18.7 0.5 0.0018 17.5 0.3 1.7 1 0 0 1 1 1 1 EF hand Pyr_redox_3 PF13738.1 AEO60530.1 - 0.0031 17.6 0.0 1.2 9.1 0.0 3.2 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_8 PF13833.1 AEO60530.1 - 0.069 12.7 0.0 3.6 7.2 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain pair PTPS PF01242.14 AEO60530.1 - 0.12 12.1 0.0 5.1 6.7 0.0 2.4 2 0 0 2 2 2 0 6-pyruvoyl tetrahydropterin synthase Glyco_hydro_3 PF00933.16 AEO60531.1 - 8.8e-59 198.9 0.0 1.2e-58 198.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 AEO60531.1 - 4.5e-39 134.3 0.0 8e-39 133.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 AEO60531.1 - 0.019 14.8 0.0 0.14 12.0 0.0 2.2 1 1 0 1 1 1 0 Fibronectin type III-like domain Glyco_hydro_12 PF01670.11 AEO60532.1 - 1.2e-52 177.8 0.4 2.1e-52 177.0 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 DUF3805 PF12712.2 AEO60532.1 - 0.004 16.9 0.3 0.0068 16.2 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3805) PRK PF00485.13 AEO60533.1 - 4.9e-56 189.3 0.0 6.8e-56 188.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 AEO60533.1 - 3.3e-40 137.5 0.0 5.2e-40 136.8 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_17 PF13207.1 AEO60533.1 - 2.6e-09 37.9 0.1 7.7e-09 36.4 0.1 1.9 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AEO60533.1 - 2.4e-06 27.8 0.0 6.1e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain CPT PF07931.7 AEO60533.1 - 8.4e-05 22.2 0.0 0.00036 20.1 0.0 2.1 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.1 AEO60533.1 - 0.00011 22.0 0.0 0.001 18.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 AEO60533.1 - 0.0027 18.0 0.2 0.011 16.0 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.1 AEO60533.1 - 0.0039 16.6 0.1 0.014 14.8 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain Zeta_toxin PF06414.7 AEO60533.1 - 0.0074 15.4 0.0 0.014 14.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin NB-ARC PF00931.17 AEO60533.1 - 0.0096 14.8 0.0 0.017 13.9 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain MobB PF03205.9 AEO60533.1 - 0.011 15.3 0.2 0.043 13.5 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 AEO60533.1 - 0.024 14.4 0.2 0.094 12.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_16 PF13191.1 AEO60533.1 - 0.044 13.7 0.0 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain T2SE PF00437.15 AEO60533.1 - 0.056 12.3 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ArgK PF03308.11 AEO60533.1 - 0.13 11.0 0.1 0.3 9.8 0.0 1.5 2 0 0 2 2 2 0 ArgK protein DUF258 PF03193.11 AEO60533.1 - 0.14 11.2 0.0 0.29 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 CLTH PF10607.4 AEO60534.1 - 4.6e-32 110.7 0.3 6.9e-32 110.1 0.2 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 AEO60534.1 - 2.4e-10 39.7 0.0 4.5e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 LisH ETC_C1_NDUFA4 PF04800.7 AEO60535.1 - 2.9e-38 129.7 0.2 4.9e-38 129.0 0.1 1.4 1 0 0 1 1 1 1 ETC complex I subunit conserved region F1F0-ATPsyn_F PF10791.4 AEO60536.1 - 7.2e-42 141.5 0.8 8.1e-42 141.3 0.5 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.4 AEO60536.1 - 0.11 12.5 0.1 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f Aminotran_1_2 PF00155.16 AEO60538.1 - 8.4e-12 44.7 0.0 1e-09 37.8 0.0 2.6 3 0 0 3 3 3 2 Aminotransferase class I and II Serglycin PF04360.7 AEO60538.1 - 0.052 13.2 0.1 0.052 13.2 0.1 4.1 4 0 0 4 4 4 0 Serglycin RNase_Zc3h12a PF11977.3 AEO60538.1 - 0.11 12.2 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain Secretin_N PF03958.12 AEO60538.1 - 2.5 8.3 0.0 2.5 8.3 0.0 4.1 3 1 0 3 3 3 0 Bacterial type II/III secretion system short domain CMAS PF02353.15 AEO60539.1 - 4e-47 160.5 0.0 5.8e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 AEO60539.1 - 3.6e-09 36.5 0.0 5.9e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO60539.1 - 3.7e-07 30.5 0.0 9.1e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO60539.1 - 1.3e-06 28.9 0.0 2.5e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO60539.1 - 0.00014 21.4 0.0 0.00022 20.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO60539.1 - 0.0059 17.0 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO60539.1 - 0.0066 16.4 0.1 0.023 14.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain RHH_1 PF01402.16 AEO60539.1 - 0.019 14.8 0.0 0.047 13.5 0.0 1.7 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family Met_10 PF02475.11 AEO60539.1 - 0.025 14.1 0.0 0.035 13.6 0.0 1.1 1 0 0 1 1 1 0 Met-10+ like-protein DUF938 PF06080.7 AEO60539.1 - 0.027 14.0 0.0 0.16 11.5 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF938) HCV_capsid PF01543.12 AEO60539.1 - 0.14 12.1 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Hepatitis C virus capsid protein RNase_T PF00929.19 AEO60540.1 - 1.5e-25 90.3 0.0 2.7e-25 89.5 0.0 1.4 2 0 0 2 2 2 1 Exonuclease DNA_pol_A_exo1 PF01612.15 AEO60540.1 - 0.0018 17.8 0.0 0.011 15.1 0.0 2.2 1 1 0 1 1 1 1 3'-5' exonuclease MOZ_SAS PF01853.13 AEO60541.1 - 3.7e-84 280.6 0.1 5.3e-84 280.1 0.1 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 AEO60541.1 - 5.8e-19 67.5 0.0 3.2e-18 65.1 0.0 2.2 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Acetyltransf_1 PF00583.19 AEO60541.1 - 0.045 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family TUDOR PF00567.19 AEO60541.1 - 0.062 13.1 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Tudor domain Acetyltransf_7 PF13508.1 AEO60541.1 - 0.11 12.7 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain He_PIG_assoc PF10632.4 AEO60541.1 - 0.13 11.6 0.1 0.3 10.4 0.0 1.5 1 0 0 1 1 1 0 He_PIG associated, NEW1 domain of bacterial glycohydrolase zf-C2H2_6 PF13912.1 AEO60541.1 - 0.57 10.1 3.3 1.5 8.8 1.7 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger MCM PF00493.18 AEO60542.1 - 4.4e-138 459.6 0.6 4.4e-138 459.6 0.4 1.5 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 AEO60542.1 - 9.5e-20 71.2 2.0 1.5e-19 70.6 0.0 2.3 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 AEO60542.1 - 1.4e-07 30.8 0.0 4.5e-07 29.2 0.0 1.9 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 AEO60542.1 - 0.00046 19.7 0.0 0.001 18.5 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 AEO60542.1 - 0.0016 18.0 0.0 0.0032 17.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 AEO60542.1 - 0.0086 15.7 0.0 0.02 14.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) SapB_1 PF05184.10 AEO60542.1 - 0.089 12.6 3.0 3.8 7.4 0.2 3.5 3 0 0 3 3 3 0 Saposin-like type B, region 1 Polysacc_deac_1 PF01522.16 AEO60543.1 - 7e-13 48.2 0.0 2.2e-12 46.6 0.0 1.8 1 1 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 AEO60543.1 - 0.041 13.3 0.0 0.079 12.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) TRAPPC-Trs85 PF12739.2 AEO60544.1 - 1.2e-120 402.9 3.2 1.9e-120 402.2 2.2 1.2 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Menin PF05053.8 AEO60544.1 - 2.8 6.0 6.1 4.3 5.3 4.2 1.2 1 0 0 1 1 1 0 Menin Snf7 PF03357.16 AEO60545.1 - 4.1e-17 62.0 7.9 6.3e-17 61.4 5.5 1.2 1 0 0 1 1 1 1 Snf7 tRNA_synt_1c_R2 PF04557.10 AEO60545.1 - 0.0063 17.1 2.0 0.019 15.6 1.4 1.8 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 YlqD PF11068.3 AEO60545.1 - 3.7 7.6 7.8 9.5 6.2 1.4 2.4 2 0 0 2 2 2 0 YlqD protein SAP PF02037.22 AEO60546.1 - 3.8e-08 32.6 0.2 8.1e-08 31.5 0.2 1.6 1 0 0 1 1 1 1 SAP domain zf-C3HC4 PF00097.20 AEO60546.1 - 1.2e-06 28.0 14.5 1.2e-06 28.0 10.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AEO60546.1 - 1.5e-06 28.0 15.4 1.5e-06 28.0 10.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AEO60546.1 - 5.6e-06 25.9 11.7 5.6e-06 25.9 8.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO60546.1 - 1.7e-05 24.4 13.6 1.7e-05 24.4 9.4 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 AEO60546.1 - 2e-05 24.3 18.9 2.3e-05 24.1 9.7 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_6 PF14835.1 AEO60546.1 - 0.0001 21.9 4.8 0.0001 21.9 3.3 2.3 2 0 0 2 2 2 1 zf-RING of BARD1-type protein U-box PF04564.10 AEO60546.1 - 0.00033 20.5 0.0 0.00076 19.3 0.0 1.7 1 0 0 1 1 1 1 U-box domain zf-RING_UBOX PF13445.1 AEO60546.1 - 0.00047 19.8 6.1 0.00047 19.8 4.2 2.8 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 AEO60546.1 - 0.0014 18.4 13.9 0.0014 18.4 9.6 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 AEO60546.1 - 0.017 14.6 5.1 0.017 14.6 3.5 3.1 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain Mob_synth_C PF06463.8 AEO60546.1 - 0.029 14.0 3.5 0.073 12.7 2.4 1.6 1 0 0 1 1 1 0 Molybdenum Cofactor Synthesis C zf-rbx1 PF12678.2 AEO60546.1 - 0.093 12.8 10.9 0.037 14.1 5.1 2.1 2 0 0 2 2 2 0 RING-H2 zinc finger zf-Apc11 PF12861.2 AEO60546.1 - 0.093 12.5 3.1 0.25 11.1 2.1 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-P11 PF03854.9 AEO60546.1 - 2.2 7.8 15.1 0.77 9.2 6.5 2.3 2 0 0 2 2 2 0 P-11 zinc finger INCENP_ARK-bind PF03941.10 AEO60547.1 - 2.1e-19 69.0 0.2 7.1e-19 67.4 0.2 2.0 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region CAF-1_p150 PF11600.3 AEO60547.1 - 0.002 17.5 29.2 0.002 17.5 20.3 5.4 6 0 0 6 6 6 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF3786 PF12654.2 AEO60548.1 - 0.019 14.2 0.3 0.025 13.8 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3786) RVT_1 PF00078.22 AEO60548.1 - 0.029 13.7 0.2 0.03 13.6 0.1 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DnaJ PF00226.26 AEO60549.1 - 3.6e-18 65.0 0.3 6.6e-18 64.2 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain PDZ_1 PF12812.2 AEO60550.1 - 4.6e-51 170.6 0.0 1.7e-30 104.7 0.0 2.5 2 0 0 2 2 2 2 PDZ-like domain PDZ_2 PF13180.1 AEO60550.1 - 9.8e-20 70.2 0.2 6.3e-06 26.0 0.0 4.5 4 0 0 4 4 4 4 PDZ domain Trypsin_2 PF13365.1 AEO60550.1 - 6.8e-14 51.8 0.0 9.2e-13 48.2 0.0 2.7 2 1 1 3 3 3 1 Trypsin-like peptidase domain PDZ PF00595.19 AEO60550.1 - 9.8e-12 44.8 0.0 9.9e-05 22.4 0.0 4.3 4 0 0 4 4 4 2 PDZ domain (Also known as DHR or GLGF) Tricorn_PDZ PF14685.1 AEO60550.1 - 0.00054 19.6 0.2 0.82 9.4 0.0 4.1 4 0 0 4 4 4 1 Tricorn protease PDZ domain Trypsin PF00089.21 AEO60550.1 - 0.00097 18.7 0.0 0.0029 17.2 0.0 1.8 1 1 0 1 1 1 1 Trypsin Peptidase_S7 PF00949.16 AEO60550.1 - 0.16 11.3 0.1 0.38 10.1 0.1 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S46 PF10459.4 AEO60550.1 - 0.36 9.1 0.1 0.74 8.1 0.0 1.4 1 0 0 1 1 1 0 Peptidase S46 DUF31 PF01732.11 AEO60550.1 - 0.5 9.6 0.3 0.76 9.0 0.2 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF31) Avl9 PF09794.4 AEO60551.1 - 4.2e-15 55.1 0.0 4.6e-15 54.9 0.0 1.0 1 0 0 1 1 1 1 Transport protein Avl9 Avl9 PF09794.4 AEO60552.1 - 5.4e-67 225.9 0.0 7.2e-67 225.4 0.0 1.2 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.5 AEO60552.1 - 3.6e-05 23.4 0.0 7.3e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis DUF1205 PF06722.7 AEO60552.1 - 0.052 13.7 0.1 2.9 8.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1205) Pkinase PF00069.20 AEO60553.1 - 3.6e-73 245.9 0.0 4.4e-73 245.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO60553.1 - 6.3e-32 110.6 0.0 8.1e-32 110.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 AEO60553.1 - 2.2e-05 23.6 0.0 7.1e-05 21.9 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 AEO60553.1 - 0.00011 21.2 0.0 0.022 13.7 0.0 2.2 1 1 1 2 2 2 2 Kinase-like APH PF01636.18 AEO60553.1 - 0.00039 20.2 0.1 0.0012 18.5 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 AEO60553.1 - 0.02 14.2 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Phosphorylase PF00343.15 AEO60554.1 - 4.1e-260 864.6 0.0 5.3e-260 864.2 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Coatomer_b_Cpla PF14806.1 AEO60554.1 - 0.034 13.8 0.0 0.084 12.5 0.0 1.6 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform PP1_bind PF15276.1 AEO60555.1 - 0.23 11.5 1.3 1.6 8.8 0.0 2.4 2 0 0 2 2 2 0 Protein phosphatase 1 binding G-alpha PF00503.15 AEO60556.1 - 1.3e-126 422.4 0.7 1.5e-126 422.1 0.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 AEO60556.1 - 1.5e-15 56.9 0.6 4.5e-10 39.0 0.1 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 AEO60556.1 - 0.00026 20.1 1.9 0.11 11.6 1.3 2.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 AEO60556.1 - 0.0019 18.7 0.2 1.1 9.7 0.0 2.7 3 0 0 3 3 3 2 Miro-like protein AAA_29 PF13555.1 AEO60556.1 - 0.054 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cullin PF00888.17 AEO60557.1 - 3.9e-203 676.2 10.5 6e-203 675.6 7.3 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 AEO60557.1 - 1.1e-26 92.4 5.0 1.1e-26 92.4 3.4 2.8 3 0 0 3 3 3 1 Cullin protein neddylation domain WGG PF10273.4 AEO60557.1 - 0.49 10.5 4.3 20 5.3 0.0 4.2 4 0 0 4 4 4 0 Pre-rRNA-processing protein TSR2 DUF2569 PF10754.4 AEO60558.1 - 2.7 8.1 5.6 2.6 8.2 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) Mit_KHE1 PF10173.4 AEO60559.1 - 6.1e-66 221.8 1.8 7.8e-66 221.4 1.2 1.1 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related GATA PF00320.22 AEO60561.1 - 1.7e-14 52.8 2.9 2.8e-14 52.1 2.0 1.4 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 AEO60561.1 - 0.08 12.2 0.5 0.14 11.5 0.4 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding Striatin PF08232.7 AEO60561.1 - 2.6 8.3 29.2 1.5 9.1 8.0 3.1 2 1 1 3 3 3 0 Striatin family ADIP PF11559.3 AEO60561.1 - 7.2 6.4 34.7 0.54 10.1 14.3 3.1 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DUF3584 PF12128.3 AEO60561.1 - 7.8 3.6 32.2 0.96 6.6 17.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) KH_1 PF00013.24 AEO60562.1 - 0.024 14.2 0.1 0.082 12.5 0.0 1.9 2 0 0 2 2 2 0 KH domain Pfg27 PF09216.5 AEO60562.1 - 0.037 13.6 0.0 0.07 12.7 0.0 1.5 1 0 0 1 1 1 0 Pfg27 KH_4 PF13083.1 AEO60562.1 - 0.037 13.6 0.1 0.091 12.4 0.1 1.6 1 0 0 1 1 1 0 KH domain Ribosomal_60s PF00428.14 AEO60562.1 - 0.55 10.6 8.2 1.2 9.6 5.7 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein ADH_zinc_N PF00107.21 AEO60563.1 - 7.4e-18 64.3 0.1 1.3e-17 63.5 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 AEO60563.1 - 3.6e-11 44.0 0.3 9.2e-11 42.7 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AEO60563.1 - 0.00033 20.3 0.0 0.0011 18.6 0.0 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ras PF00071.17 AEO60565.1 - 7.6e-59 197.7 0.3 8.9e-59 197.4 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AEO60565.1 - 7.8e-19 68.3 0.0 1.1e-18 67.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AEO60565.1 - 5.8e-09 35.4 0.0 6.4e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 AEO60565.1 - 7e-07 28.8 0.2 5.2e-06 26.0 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 AEO60565.1 - 0.00036 19.8 0.4 0.00092 18.5 0.2 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.18 AEO60565.1 - 0.0014 18.5 0.0 0.0017 18.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 AEO60565.1 - 0.022 13.9 0.2 0.03 13.4 0.1 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region IstB_IS21 PF01695.12 AEO60565.1 - 0.056 12.8 0.7 0.72 9.2 0.1 2.3 1 1 1 2 2 2 0 IstB-like ATP binding protein ATP_bind_1 PF03029.12 AEO60565.1 - 0.083 12.4 3.0 0.51 9.8 0.1 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_25 PF13481.1 AEO60565.1 - 0.17 11.2 0.2 0.24 10.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain MoCF_biosynth PF00994.19 AEO60566.1 - 9.8e-32 109.3 0.0 1.5e-31 108.7 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain PcrB PF01884.12 AEO60566.1 - 0.12 11.5 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 PcrB family ParA PF10609.4 AEO60567.1 - 1.5e-34 117.7 0.0 3.1e-34 116.6 0.0 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 AEO60567.1 - 7.5e-15 54.8 0.0 1.1e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 AEO60567.1 - 7.1e-06 26.0 0.0 2e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 AEO60567.1 - 2.9e-05 23.2 0.4 0.00061 18.9 0.1 2.3 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.1 AEO60567.1 - 4.8e-05 22.8 0.0 8.5e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain MipZ PF09140.6 AEO60567.1 - 0.00022 20.4 0.0 0.00052 19.1 0.0 1.6 1 1 0 1 1 1 1 ATPase MipZ AAA_26 PF13500.1 AEO60567.1 - 0.00054 19.6 0.1 0.045 13.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 AEO60567.1 - 0.0012 18.0 0.0 0.0022 17.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_30 PF13604.1 AEO60567.1 - 0.0017 17.9 0.0 0.0027 17.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 AEO60567.1 - 0.0079 15.1 0.2 0.012 14.5 0.1 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 AEO60567.1 - 0.0079 15.9 0.4 0.17 11.6 0.2 2.7 3 0 0 3 3 3 1 Part of AAA domain SRP54 PF00448.17 AEO60567.1 - 0.01 15.3 0.0 0.02 14.3 0.0 1.6 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Fer4_NifH PF00142.13 AEO60567.1 - 0.01 15.0 0.0 0.17 11.0 0.0 2.3 2 1 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_22 PF13401.1 AEO60567.1 - 0.013 15.6 0.0 0.044 13.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain Ras PF00071.17 AEO60567.1 - 0.016 14.6 0.1 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Ras family RNA_helicase PF00910.17 AEO60567.1 - 0.018 15.2 0.0 0.036 14.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.1 AEO60567.1 - 0.021 14.8 0.0 0.091 12.7 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_17 PF13207.1 AEO60567.1 - 0.028 15.2 0.0 0.097 13.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 AEO60567.1 - 0.04 12.7 0.1 0.063 12.1 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.7 AEO60567.1 - 0.048 13.3 0.2 0.078 12.6 0.1 1.3 1 0 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.7 AEO60567.1 - 0.06 12.4 0.1 0.11 11.5 0.0 1.4 2 0 0 2 2 2 0 Zeta toxin AAA_5 PF07728.9 AEO60567.1 - 0.09 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ArgK PF03308.11 AEO60567.1 - 0.097 11.4 0.1 0.15 10.8 0.1 1.2 1 0 0 1 1 1 0 ArgK protein AAA_14 PF13173.1 AEO60567.1 - 0.1 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 AEO60567.1 - 0.11 11.7 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 Chromatin associated protein KTI12 VirE PF05272.6 AEO60567.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E DnaB_C PF03796.10 AEO60567.1 - 0.12 11.1 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_29 PF13555.1 AEO60567.1 - 0.13 11.7 0.1 0.28 10.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 AEO60567.1 - 0.14 12.0 0.1 0.99 9.3 0.1 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase UPF0079 PF02367.12 AEO60567.1 - 0.18 11.4 0.2 0.32 10.6 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 ECM11 PF15463.1 AEO60568.1 - 3.5e-44 150.4 3.0 3.5e-44 150.4 2.1 2.7 2 1 1 3 3 3 1 Extracellular mutant protein 11 TMEM247 PF15444.1 AEO60568.1 - 0.3 10.8 10.7 0.045 13.5 3.9 2.1 2 0 0 2 2 2 0 Transmembrane protein 247 SRP54 PF00448.17 AEO60569.1 - 4.1e-07 29.6 0.0 5.8e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_17 PF13207.1 AEO60569.1 - 1.7e-06 28.8 0.2 8.6e-06 26.5 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AEO60569.1 - 4.9e-05 23.4 0.0 0.00015 21.8 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 AEO60569.1 - 0.00068 19.9 0.0 0.0021 18.3 0.0 1.9 2 0 0 2 2 1 1 AAA domain NACHT PF05729.7 AEO60569.1 - 0.0011 18.5 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 NACHT domain ArgK PF03308.11 AEO60569.1 - 0.0012 17.6 0.0 0.0021 16.8 0.0 1.3 1 0 0 1 1 1 1 ArgK protein cobW PF02492.14 AEO60569.1 - 0.0017 17.8 0.0 0.0025 17.2 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 AEO60569.1 - 0.0025 17.5 0.0 0.0038 16.9 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 AEO60569.1 - 0.0055 16.9 0.0 0.0095 16.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 AEO60569.1 - 0.0057 15.7 0.0 0.0099 14.9 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin KAP_NTPase PF07693.9 AEO60569.1 - 0.0059 15.6 0.0 0.0082 15.1 0.0 1.1 1 0 0 1 1 1 1 KAP family P-loop domain PRK PF00485.13 AEO60569.1 - 0.0068 15.9 0.0 0.016 14.8 0.0 1.5 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family UPF0079 PF02367.12 AEO60569.1 - 0.0078 15.8 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_31 PF13614.1 AEO60569.1 - 0.011 15.6 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 AEO60569.1 - 0.015 15.0 0.1 0.05 13.3 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain AAA_14 PF13173.1 AEO60569.1 - 0.015 15.2 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 AEO60569.1 - 0.016 15.4 0.0 0.031 14.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.1 AEO60569.1 - 0.017 15.0 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 AEO60569.1 - 0.022 14.9 0.0 0.039 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 AEO60569.1 - 0.022 14.4 0.1 0.035 13.7 0.1 1.3 1 0 0 1 1 1 0 NTPase Thymidylate_kin PF02223.12 AEO60569.1 - 0.028 13.7 0.2 0.11 11.8 0.0 1.9 2 0 0 2 2 2 0 Thymidylate kinase AAA_28 PF13521.1 AEO60569.1 - 0.061 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 AEO60569.1 - 0.062 12.1 0.0 0.092 11.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain ATP_bind_1 PF03029.12 AEO60569.1 - 0.07 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_5 PF07728.9 AEO60569.1 - 0.077 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 AEO60569.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain CPT PF07931.7 AEO60569.1 - 0.12 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein ArsA_ATPase PF02374.10 AEO60569.1 - 0.21 10.6 0.0 0.35 9.8 0.0 1.3 1 0 0 1 1 1 0 Anion-transporting ATPase adh_short PF00106.20 AEO60570.1 - 1.6e-63 213.5 11.7 1.2e-32 113.1 0.5 2.8 3 0 0 3 3 3 2 short chain dehydrogenase KR PF08659.5 AEO60570.1 - 1e-31 109.9 4.6 4.2e-15 55.8 0.1 2.6 3 0 0 3 3 3 2 KR domain MaoC_dehydratas PF01575.14 AEO60570.1 - 5.1e-31 106.6 0.0 1.1e-30 105.5 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain Epimerase PF01370.16 AEO60570.1 - 0.0002 20.9 5.0 0.011 15.2 0.1 2.8 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 AEO60570.1 - 0.0019 17.2 0.7 0.032 13.3 0.3 2.4 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF4161 PF13722.1 AEO60570.1 - 0.025 14.8 0.8 3.1 8.1 0.0 2.3 2 0 0 2 2 2 0 C-terminal domain on CstA (DUF4161) 3HCDH_N PF02737.13 AEO60570.1 - 2.4 7.7 7.8 1.6 8.3 0.6 3.0 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF500 PF04366.7 AEO60571.1 - 6e-31 106.4 0.0 1.1e-30 105.7 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) F-box PF00646.28 AEO60573.1 - 0.0067 16.0 0.6 0.021 14.4 0.1 2.2 2 0 0 2 2 2 1 F-box domain F-box-like_2 PF13013.1 AEO60573.1 - 0.16 11.6 0.5 0.9 9.2 0.0 2.4 2 2 0 2 2 2 0 F-box-like domain zf-RING_4 PF14570.1 AEO60574.1 - 0.0054 16.2 5.0 0.0054 16.2 3.5 4.5 6 1 0 6 6 6 1 RING/Ubox like zinc-binding domain Actin PF00022.14 AEO60575.1 - 3.1e-17 62.0 0.0 1.5e-14 53.2 0.0 2.4 3 0 0 3 3 3 2 Actin Suf PF05843.9 AEO60575.1 - 0.27 10.9 9.0 0.44 10.2 6.2 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Ndc1_Nup PF09531.5 AEO60575.1 - 6.8 4.9 4.3 9.6 4.4 3.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pex14_N PF04695.8 AEO60575.1 - 7.6 6.5 13.3 0.77 9.8 5.2 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Borrelia_P83 PF05262.6 AEO60575.1 - 9.5 4.3 10.0 16 3.6 6.9 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein Ribonuc_L-PSP PF01042.16 AEO60576.1 - 4e-27 94.3 0.0 4.4e-27 94.2 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP BID PF06393.6 AEO60576.1 - 0.087 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 BH3 interacting domain (BID) Kelch_5 PF13854.1 AEO60577.1 - 2.7e-14 52.7 3.8 3.7e-12 45.8 0.5 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 AEO60577.1 - 6.9e-07 28.9 1.1 0.18 11.5 0.0 4.3 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.1 AEO60577.1 - 2.8e-05 24.0 1.1 0.049 13.8 0.1 4.0 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 AEO60577.1 - 0.00012 21.5 3.5 0.75 9.3 0.6 3.8 3 0 0 3 3 3 2 Kelch motif Lactamase_B PF00753.22 AEO60579.1 - 1.9e-06 27.6 0.6 0.04 13.5 0.0 2.2 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Sulf_transp PF04143.9 AEO60580.1 - 1.3e-12 47.5 29.3 7.2e-09 35.5 6.4 4.6 3 2 0 3 3 3 2 Sulphur transport P12 PF12669.2 AEO60580.1 - 0.29 11.3 2.0 3.4 7.9 0.0 2.9 3 0 0 3 3 3 0 Virus attachment protein p12 family GTP_EFTU PF00009.22 AEO60582.1 - 4e-50 169.8 0.0 7e-50 169.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 AEO60582.1 - 8.8e-23 79.9 0.0 2.5e-22 78.5 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 AEO60582.1 - 6.2e-12 45.2 0.0 1.4e-10 40.8 0.0 2.5 1 1 0 1 1 1 1 Elongation factor G C-terminus MMR_HSR1 PF01926.18 AEO60582.1 - 0.036 14.0 0.0 0.07 13.0 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Vps5 PF09325.5 AEO60583.1 - 1.9e-13 50.2 0.6 1.9e-13 50.2 0.4 2.0 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.19 AEO60583.1 - 1.3e-08 34.6 0.0 2.5e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 PX domain PAT1 PF09770.4 AEO60583.1 - 0.16 10.1 13.8 0.24 9.5 9.6 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ADH_N PF08240.7 AEO60584.1 - 8.1e-20 70.6 0.3 2e-19 69.3 0.2 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AEO60584.1 - 6.9e-17 61.2 0.3 2.8e-13 49.5 0.0 2.4 2 0 0 2 2 2 2 Zinc-binding dehydrogenase Pyr_redox_3 PF13738.1 AEO60584.1 - 0.0064 16.5 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 AEO60584.1 - 0.0075 16.3 0.1 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 AEO60584.1 - 0.012 15.4 0.8 0.028 14.2 0.6 1.6 1 0 0 1 1 1 0 ThiF family UDPG_MGDP_dh_N PF03721.9 AEO60584.1 - 0.018 14.4 0.2 0.038 13.3 0.2 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_8 PF13450.1 AEO60584.1 - 0.019 14.9 0.6 0.071 13.1 0.4 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ApbA PF02558.11 AEO60584.1 - 0.028 13.8 0.0 0.046 13.1 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DAO PF01266.19 AEO60584.1 - 0.04 12.8 0.1 0.071 12.0 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.9 AEO60584.1 - 0.066 11.6 0.7 0.092 11.1 0.5 1.2 1 0 0 1 1 1 0 HI0933-like protein TrkA_N PF02254.13 AEO60584.1 - 0.074 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox PF00070.22 AEO60584.1 - 0.087 13.2 0.4 0.28 11.6 0.3 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 AEO60584.1 - 0.13 11.0 1.4 0.19 10.5 1.0 1.2 1 0 0 1 1 1 0 FAD binding domain 2-Hacid_dh_C PF02826.14 AEO60584.1 - 0.16 11.1 0.1 0.27 10.3 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 AEO60584.1 - 0.17 11.7 1.1 1.3 8.8 0.3 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase JAB PF01398.16 AEO60585.1 - 1.2e-10 41.1 0.0 2.5e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 AEO60585.1 - 0.054 13.5 0.6 0.42 10.6 0.5 2.2 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function HipA_N PF07805.7 AEO60585.1 - 0.11 12.6 0.1 3.7 7.8 0.0 2.9 3 0 0 3 3 3 0 HipA-like N-terminal domain AA_permease PF00324.16 AEO60587.1 - 1.5e-107 359.9 34.0 1.9e-107 359.5 23.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AEO60587.1 - 7.2e-21 74.2 34.3 9.6e-21 73.7 23.7 1.0 1 0 0 1 1 1 1 Amino acid permease Orthoreo_P10 PF07204.6 AEO60587.1 - 0.02 14.6 1.7 0.068 12.9 1.2 2.0 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Utp21 PF04192.7 AEO60588.1 - 1.4e-80 269.8 0.0 1.9e-80 269.4 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 AEO60588.1 - 2.7e-25 87.2 22.4 5.9e-06 25.9 0.7 9.2 9 0 0 9 9 9 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 AEO60588.1 - 2.1e-05 22.9 0.0 3.5e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain Nup160 PF11715.3 AEO60588.1 - 0.002 16.3 0.6 15 3.5 0.0 3.9 3 1 1 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 AEO60588.1 - 0.0054 15.5 0.1 0.65 8.6 0.0 2.6 1 1 0 2 2 2 2 Nup133 N terminal like His_Phos_2 PF00328.17 AEO60589.1 - 6.4e-70 236.1 0.1 9.2e-70 235.6 0.1 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 AEO60589.1 - 8e-09 35.2 0.0 1.5e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain His_Phos_2 PF00328.17 AEO60590.1 - 2.7e-19 69.7 0.0 3.1e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Mucin PF01456.12 AEO60591.1 - 0.74 9.5 13.3 0.89 9.3 9.2 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF2296 PF10058.4 AEO60592.1 - 0.032 13.9 0.3 0.032 13.9 0.2 2.4 2 1 1 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) IBR PF01485.16 AEO60592.1 - 2.7 7.9 10.7 9.2 6.2 7.4 1.8 1 1 0 1 1 1 0 IBR domain FLYWCH PF04500.11 AEO60592.1 - 2.7 7.9 11.3 1.5 8.8 0.1 2.1 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-B_box PF00643.19 AEO60592.1 - 4.8 7.1 11.6 4.9 7.1 6.5 2.0 2 1 1 3 3 3 0 B-box zinc finger Baculo_LEF5_C PF11792.3 AEO60592.1 - 5.3 6.5 0.0 5.3 6.5 0.0 3.2 3 1 0 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain Glyco_hydro_76 PF03663.9 AEO60593.1 - 1.1e-51 176.3 7.2 1.3e-51 176.1 5.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 AEO60593.1 - 5.7e-06 25.5 0.8 0.024 13.6 0.0 2.5 1 1 1 2 2 2 2 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.8 AEO60593.1 - 0.003 16.8 0.1 0.061 12.6 0.0 2.3 2 0 0 2 2 2 1 D-glucuronyl C5-epimerase C-terminus DUF1680 PF07944.7 AEO60593.1 - 0.0038 15.5 0.1 0.45 8.7 0.0 2.1 2 0 0 2 2 2 2 Putative glycosyl hydrolase of unknown function (DUF1680) TFCD_C PF12612.3 AEO60594.1 - 2.8e-37 128.0 0.7 9.3e-37 126.3 0.2 2.2 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal DUF1556 PF07590.6 AEO60596.1 - 0.088 13.0 0.1 0.088 13.0 0.1 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1556) SSP160 PF06933.6 AEO60596.1 - 0.18 9.7 6.6 0.24 9.3 4.6 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.3 AEO60596.1 - 0.29 10.8 8.5 0.75 9.5 5.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DcpS_C PF11969.3 AEO60597.1 - 1.3e-30 105.9 0.0 2.3e-30 105.1 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 AEO60597.1 - 1.7e-28 99.1 0.0 2.7e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal Hexokinase_2 PF03727.11 AEO60598.1 - 4e-21 75.3 0.0 6.4e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 Hexokinase MFS_1 PF07690.11 AEO60598.1 - 2.2e-19 69.4 44.3 1.7e-14 53.3 11.4 2.8 2 0 0 2 2 2 2 Major Facilitator Superfamily Hexokinase_1 PF00349.16 AEO60598.1 - 6e-13 48.5 0.0 7.3e-12 45.0 0.0 2.1 1 1 1 2 2 2 1 Hexokinase DUF1509 PF07420.6 AEO60598.1 - 0.033 13.4 5.6 0.051 12.8 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) Corona_nucleoca PF00937.13 AEO60598.1 - 0.13 11.1 1.3 0.21 10.5 0.9 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein SMC_Nse1 PF07574.8 AEO60600.1 - 9.4e-40 136.3 0.0 2.5e-39 135.0 0.0 1.6 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 AEO60600.1 - 6.1e-13 48.5 8.1 9.2e-13 47.9 5.6 1.3 1 0 0 1 1 1 1 RING-like domain HTH_27 PF13463.1 AEO60600.1 - 0.047 14.0 0.0 0.15 12.4 0.0 1.9 1 0 0 1 1 1 0 Winged helix DNA-binding domain zf-tcix PF14952.1 AEO60600.1 - 0.069 12.4 0.1 0.069 12.4 0.1 2.1 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding PaaX PF07848.7 AEO60600.1 - 0.085 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 PaaX-like protein HTH_IclR PF09339.5 AEO60600.1 - 0.12 12.0 0.1 0.3 10.6 0.1 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain zf-ribbon_3 PF13248.1 AEO60600.1 - 0.82 8.9 8.3 6.3 6.1 5.7 2.2 1 1 0 1 1 1 0 zinc-ribbon domain C1_1 PF00130.17 AEO60600.1 - 1.3 8.8 6.8 0.2 11.4 1.8 1.7 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.2 AEO60600.1 - 4.8 7.0 8.0 27 4.6 5.5 2.0 1 1 0 1 1 1 0 Double zinc ribbon DUF4381 PF14316.1 AEO60601.1 - 0.056 13.5 0.6 0.35 10.9 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF3328 PF11807.3 AEO60601.1 - 0.23 11.1 1.0 12 5.5 0.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF3328) SPRY PF00622.23 AEO60602.1 - 9.9e-10 38.5 0.1 4e-08 33.3 0.0 3.1 3 0 0 3 3 3 1 SPRY domain Myb_Cef PF11831.3 AEO60603.1 - 2.4e-61 206.8 10.5 2.4e-61 206.8 7.3 2.8 2 0 0 2 2 2 1 pre-mRNA splicing factor component Myb_DNA-bind_6 PF13921.1 AEO60603.1 - 1.5e-21 76.2 8.8 5.2e-15 55.2 2.2 3.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 AEO60603.1 - 1.5e-20 72.9 4.2 2.3e-09 37.1 0.2 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.3 AEO60603.1 - 0.01 15.6 1.5 0.69 9.8 0.0 3.5 2 1 1 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain PRMT5 PF05185.11 AEO60603.1 - 0.15 10.9 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Pkinase PF00069.20 AEO60605.1 - 1.4e-11 44.0 0.0 1.9e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO60605.1 - 0.00012 21.3 0.0 0.00016 20.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO60605.1 - 0.00076 18.5 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AEO60605.1 - 0.0046 16.7 0.8 0.034 13.8 0.4 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 AEO60605.1 - 0.05 12.6 0.0 0.08 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pyr_redox_2 PF07992.9 AEO60607.1 - 1.5e-17 64.1 0.0 2e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AEO60607.1 - 5.4e-06 26.6 0.5 0.027 14.5 0.0 2.6 1 1 2 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 AEO60607.1 - 1.2e-05 24.4 0.4 8.3e-05 21.6 0.0 2.3 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.9 AEO60607.1 - 5.8e-05 21.7 0.0 0.00013 20.5 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.1 AEO60607.1 - 8.8e-05 22.3 0.2 0.31 10.8 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 AEO60607.1 - 0.00013 21.8 0.0 0.00031 20.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 AEO60607.1 - 0.00016 20.7 0.0 0.0077 15.1 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A DAO PF01266.19 AEO60607.1 - 0.00017 20.6 0.3 0.00041 19.3 0.2 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase K_oxygenase PF13434.1 AEO60607.1 - 0.00027 19.9 0.2 0.01 14.8 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 AEO60607.1 - 0.0012 18.0 0.1 0.0046 16.0 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 AEO60607.1 - 0.0016 17.4 0.1 0.0025 16.8 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 AEO60607.1 - 0.0079 15.3 0.1 0.016 14.2 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 AEO60607.1 - 0.05 12.6 0.5 0.08 11.9 0.4 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.9 AEO60607.1 - 0.084 11.4 0.1 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase DUF4360 PF14273.1 AEO60608.1 - 6.3e-35 120.4 0.3 1.1e-34 119.7 0.2 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4360) NPV_P10 PF05531.7 AEO60609.1 - 0.056 13.6 2.9 2.6 8.3 0.8 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Filament PF00038.16 AEO60609.1 - 0.062 12.7 5.0 0.098 12.1 3.5 1.3 1 0 0 1 1 1 0 Intermediate filament protein DUF948 PF06103.6 AEO60609.1 - 0.077 12.8 1.1 0.31 10.9 0.0 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Zw10 PF06248.8 AEO60609.1 - 0.11 10.6 2.0 0.14 10.2 1.4 1.1 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 Med3 PF11593.3 AEO60609.1 - 0.12 11.6 8.6 0.17 11.1 5.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Spc7 PF08317.6 AEO60609.1 - 0.49 9.0 6.7 0.92 8.0 4.7 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein DivIVA PF05103.8 AEO60609.1 - 0.54 10.3 12.5 2.2 8.3 2.5 2.4 1 1 1 2 2 2 0 DivIVA protein V_ATPase_I PF01496.14 AEO60609.1 - 0.57 7.9 1.5 0.85 7.3 1.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CDC37_N PF03234.9 AEO60609.1 - 0.63 10.3 3.6 1 9.6 0.3 2.2 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding DUF4157 PF13699.1 AEO60609.1 - 0.71 10.0 5.7 0.18 11.9 1.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4157) Striatin PF08232.7 AEO60609.1 - 1.2 9.4 6.8 0.16 12.2 0.4 2.2 2 0 0 2 2 2 0 Striatin family REV PF00424.13 AEO60609.1 - 3.3 7.6 6.5 0.35 10.7 0.2 2.4 3 0 0 3 3 3 0 REV protein (anti-repression trans-activator protein) SPX PF03105.14 AEO60609.1 - 3.5 7.3 6.0 0.63 9.7 0.6 1.9 1 1 1 2 2 2 0 SPX domain Muted PF14942.1 AEO60609.1 - 3.9 7.3 9.2 0.95 9.3 2.6 2.2 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein AATF-Che1 PF13339.1 AEO60609.1 - 6.9 6.8 14.6 0.65 10.1 0.9 2.5 2 1 1 3 3 2 0 Apoptosis antagonizing transcription factor His_Phos_2 PF00328.17 AEO60610.1 - 2.3e-32 112.7 0.0 3.1e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 AEO60610.1 - 0.016 15.2 0.0 0.027 14.5 0.0 1.4 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) Inositol_P PF00459.20 AEO60612.1 - 1.2e-62 211.6 0.0 1.4e-62 211.4 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family MFS_1 PF07690.11 AEO60613.1 - 1.2e-34 119.6 19.9 6.9e-28 97.3 2.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO60613.1 - 2.3e-08 33.0 6.9 2.3e-08 33.0 4.8 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 AEO60613.1 - 0.00072 18.0 4.1 0.00072 18.0 2.8 2.7 2 1 0 2 2 2 1 MFS/sugar transport protein DUF791 PF05631.9 AEO60613.1 - 0.00085 18.1 0.2 0.0014 17.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF791) TRI12 PF06609.8 AEO60613.1 - 0.0014 16.9 0.5 0.0022 16.2 0.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3786 PF12654.2 AEO60614.1 - 0.12 11.6 0.1 0.14 11.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3786) Ycf54 PF10674.4 AEO60614.1 - 0.13 12.3 0.3 0.55 10.3 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2488) Apq12 PF12716.2 AEO60614.1 - 2 8.1 4.7 7.5 6.3 3.2 2.0 1 1 0 1 1 1 0 Nuclear pore assembly and biogenesis HNH_2 PF13391.1 AEO60616.1 - 4.7e-05 23.0 0.3 0.0001 22.0 0.2 1.5 1 0 0 1 1 1 1 HNH endonuclease PGBA_C PF15437.1 AEO60617.1 - 0.057 13.5 0.2 0.058 13.5 0.1 1.1 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal FlgN PF05130.7 AEO60618.1 - 0.0051 17.0 1.4 0.0081 16.4 1.0 1.4 1 0 0 1 1 1 1 FlgN protein APG6 PF04111.7 AEO60618.1 - 0.0056 15.7 0.5 0.0069 15.4 0.3 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 OmpH PF03938.9 AEO60618.1 - 0.036 13.9 0.4 0.047 13.6 0.3 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1599 PF07659.6 AEO60618.1 - 0.086 12.9 2.6 5.7 7.0 0.1 2.3 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1599) DUF1664 PF07889.7 AEO60618.1 - 0.15 11.8 0.3 0.23 11.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Fzo_mitofusin PF04799.8 AEO60618.1 - 0.2 11.0 1.1 0.29 10.5 0.8 1.2 1 0 0 1 1 1 0 fzo-like conserved region DUF724 PF05266.9 AEO60618.1 - 0.22 11.1 3.0 0.61 9.6 2.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF724) CALCOCO1 PF07888.6 AEO60618.1 - 1.5 7.0 9.3 1.9 6.7 6.5 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2852 PF11014.3 AEO60618.1 - 2.5 8.0 6.2 2.6 8.0 3.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) rve PF00665.21 AEO60619.1 - 0.00045 20.2 0.0 0.00054 20.0 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain Dioxygenase_C PF00775.16 AEO60620.1 - 1.2e-11 44.2 3.5 8.6e-11 41.4 2.4 2.1 1 1 0 1 1 1 1 Dioxygenase CarboxypepD_reg PF13620.1 AEO60620.1 - 0.052 13.6 0.2 0.82 9.7 0.1 2.4 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain His_Phos_2 PF00328.17 AEO60622.1 - 1e-55 189.4 0.0 1.2e-55 189.2 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Sec62 PF03839.11 AEO60624.1 - 7.1e-55 185.8 0.2 7.1e-55 185.8 0.1 1.9 2 0 0 2 2 2 1 Translocation protein Sec62 Zip PF02535.17 AEO60624.1 - 0.0026 16.8 2.5 0.31 10.0 3.6 2.3 3 0 0 3 3 3 1 ZIP Zinc transporter NST1 PF13945.1 AEO60624.1 - 0.3 11.1 10.1 0.097 12.7 1.9 2.2 2 0 0 2 2 2 0 Salt tolerance down-regulator SelP_N PF04592.9 AEO60624.1 - 1.1 8.5 15.2 0.12 11.7 7.4 1.6 2 0 0 2 2 2 0 Selenoprotein P, N terminal region APC_CDC26 PF10471.4 AEO60624.1 - 1.9 9.2 21.8 2.8 8.7 9.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 PLDc_2 PF13091.1 AEO60626.1 - 3.7e-14 52.5 0.1 7.4e-06 25.7 0.0 3.8 3 1 0 3 3 3 3 PLD-like domain PLDc PF00614.17 AEO60626.1 - 2.2e-09 36.8 1.6 0.0017 18.0 0.1 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif FR47 PF08445.5 AEO60627.1 - 9.3e-10 38.1 0.0 1.6e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.19 AEO60627.1 - 1.8e-06 27.8 0.1 2.8e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 AEO60627.1 - 1.1e-05 25.5 0.1 1.5e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 AEO60627.1 - 0.0019 18.2 0.0 0.0027 17.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Thioredoxin PF00085.15 AEO60628.1 - 5.3e-41 138.5 0.0 4.1e-25 87.4 0.0 3.1 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 AEO60628.1 - 2.4e-14 53.5 0.0 2.6e-05 24.1 0.0 4.0 3 1 1 4 4 4 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 AEO60628.1 - 6e-08 32.8 1.0 0.0018 18.4 0.1 4.1 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 AEO60628.1 - 1e-06 28.7 3.9 0.0069 16.4 0.0 5.0 4 2 0 4 4 4 2 Thioredoxin-like HyaE PF07449.6 AEO60628.1 - 4.6e-05 23.2 0.0 0.036 13.9 0.0 3.3 3 0 0 3 3 3 1 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.1 AEO60628.1 - 0.00087 19.2 0.3 0.089 12.8 0.0 3.4 3 0 0 3 3 3 1 Thioredoxin-like UBN_AB PF14075.1 AEO60628.1 - 0.01 15.5 0.7 0.016 14.8 0.5 1.2 1 0 0 1 1 1 0 Ubinuclein conserved middle domain Tyr-DNA_phospho PF06087.7 AEO60629.1 - 1.8e-126 422.3 0.0 2.2e-126 422.0 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 AEO60629.1 - 0.0057 16.4 0.0 0.31 10.7 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain Pyr_redox_2 PF07992.9 AEO60630.1 - 1.4e-17 64.2 0.0 2.5e-17 63.4 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AEO60630.1 - 7.1e-10 39.1 2.3 6.7e-07 29.6 0.8 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AEO60630.1 - 9.4e-09 35.6 0.4 2.6e-05 24.4 0.0 3.0 1 1 2 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 AEO60630.1 - 6.6e-05 21.9 0.1 0.0084 15.0 0.0 2.4 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) End3 PF12761.2 AEO60631.1 - 1.5e-74 249.8 3.6 2.2e-74 249.3 2.5 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.2 AEO60631.1 - 2.7e-50 168.4 0.0 1.1e-48 163.2 0.0 2.3 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 AEO60631.1 - 5.2e-07 28.4 0.4 1.4e-06 27.1 0.1 1.9 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 AEO60631.1 - 1.1e-06 28.0 0.1 8.8e-06 25.2 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.1 AEO60631.1 - 4.4e-06 26.7 0.0 5.7e-05 23.1 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 AEO60631.1 - 0.0001 21.8 0.4 0.0027 17.4 0.2 3.0 3 0 0 3 3 3 1 EF-hand domain MIS13 PF08202.6 AEO60631.1 - 0.0052 15.8 0.9 0.007 15.4 0.6 1.2 1 0 0 1 1 1 1 Mis12-Mtw1 protein family EF-hand_5 PF13202.1 AEO60631.1 - 0.0052 16.0 0.2 0.013 14.8 0.1 1.7 1 0 0 1 1 1 1 EF hand COG2 PF06148.6 AEO60631.1 - 0.076 12.8 2.4 0.27 11.0 0.1 2.5 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TPR_MLP1_2 PF07926.7 AEO60631.1 - 0.083 12.6 4.8 1.4 8.7 0.0 2.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein MDMPI_N PF11716.3 AEO60631.1 - 0.11 12.9 2.6 0.32 11.4 0.0 2.7 2 1 0 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain Mnd1 PF03962.10 AEO60631.1 - 1.4 8.5 8.7 6.1 6.4 6.1 1.9 1 1 0 1 1 1 0 Mnd1 family DUF641 PF04859.7 AEO60631.1 - 1.7 8.4 5.4 0.55 9.9 1.2 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DivIC PF04977.10 AEO60631.1 - 5.9 6.4 6.6 8.3 5.9 0.5 2.6 2 0 0 2 2 2 0 Septum formation initiator IncA PF04156.9 AEO60631.1 - 6.3 6.3 14.3 55 3.2 8.1 2.7 2 1 0 2 2 2 0 IncA protein Dicty_REP PF05086.7 AEO60632.1 - 1.9 6.1 1.4 3.6 5.2 1.0 1.4 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RVT_1 PF00078.22 AEO60633.1 - 8.8e-06 25.2 0.6 1.1e-05 24.9 0.4 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) YrbL-PhoP_reg PF10707.4 AEO60634.1 - 0.089 12.1 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL GRAM PF02893.15 AEO60636.1 - 1.3e-16 59.8 0.0 2.3e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 GRAM domain Serglycin PF04360.7 AEO60636.1 - 0.57 9.9 7.6 0.076 12.7 0.3 2.7 3 0 0 3 3 3 0 Serglycin CENP-B_dimeris PF09026.5 AEO60636.1 - 2.4 8.4 9.1 5.5 7.3 6.3 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain OPT PF03169.10 AEO60637.1 - 2.1e-210 700.3 32.2 2.5e-210 700.1 22.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein 5-FTHF_cyc-lig PF01812.15 AEO60638.1 - 9.7e-30 103.7 0.0 1.2e-29 103.4 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Xpo1 PF08389.7 AEO60640.1 - 5.7e-27 94.4 2.2 1.1e-26 93.4 0.3 2.6 2 1 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.14 AEO60640.1 - 0.00011 22.0 0.7 0.001 18.9 0.0 2.9 2 1 1 3 3 3 1 Importin-beta N-terminal domain HEAT_EZ PF13513.1 AEO60640.1 - 0.00068 20.0 0.1 0.69 10.4 0.0 5.1 5 0 0 5 5 5 1 HEAT-like repeat TRM PF02005.11 AEO60641.1 - 2e-105 352.8 0.0 1.4e-92 310.5 0.0 2.1 1 1 1 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_26 PF13659.1 AEO60641.1 - 0.0014 18.6 0.0 0.0041 17.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain DAGK_cat PF00781.19 AEO60642.1 - 3.5e-10 39.4 1.5 3.1e-09 36.3 0.0 2.6 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain Zip PF02535.17 AEO60642.1 - 0.031 13.3 1.0 0.044 12.7 0.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter TPP_enzyme_C PF02775.16 AEO60642.1 - 0.085 12.4 0.3 0.47 10.0 0.0 2.2 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain ABC_tran PF00005.22 AEO60643.1 - 1.6e-30 106.1 0.0 8e-18 65.0 0.0 2.7 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 AEO60643.1 - 2.8e-12 47.1 1.0 0.0012 18.9 0.1 3.2 3 0 0 3 3 3 3 AAA domain SMC_N PF02463.14 AEO60643.1 - 0.0035 16.5 0.4 4.4 6.4 0.0 3.1 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 AEO60643.1 - 0.0043 16.9 0.0 0.014 15.3 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran_2 PF12848.2 AEO60643.1 - 0.0061 16.3 1.5 0.017 14.9 1.0 1.8 1 0 0 1 1 1 1 ABC transporter ArgK PF03308.11 AEO60643.1 - 0.0078 15.0 0.3 0.0078 15.0 0.2 1.7 2 0 0 2 2 2 1 ArgK protein AAA_22 PF13401.1 AEO60643.1 - 0.013 15.6 1.2 1 9.5 0.0 3.6 3 1 0 3 3 3 0 AAA domain SbcCD_C PF13558.1 AEO60643.1 - 0.045 13.6 0.3 2.8 7.9 0.0 3.4 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 AEO60643.1 - 0.055 13.0 0.1 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Miro PF08477.8 AEO60643.1 - 0.14 12.6 0.0 0.35 11.3 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein AAA_23 PF13476.1 AEO60643.1 - 1 9.6 3.5 0.9 9.8 0.0 2.3 3 0 0 3 3 3 0 AAA domain Sugar_tr PF00083.19 AEO60644.1 - 3.1e-107 358.9 23.6 4e-107 358.6 16.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO60644.1 - 1.4e-19 70.0 40.7 1.4e-18 66.7 19.4 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily PUCC PF03209.10 AEO60644.1 - 0.0036 16.0 4.9 0.0076 15.0 3.4 1.5 1 0 0 1 1 1 1 PUCC protein DUF791 PF05631.9 AEO60644.1 - 0.0038 15.9 1.1 0.007 15.0 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF791) DUF3154 PF11351.3 AEO60644.1 - 0.56 9.9 8.2 0.28 10.9 0.3 3.5 3 1 0 4 4 4 0 Protein of unknown function (DUF3154) Sporozoite_P67 PF05642.6 AEO60645.1 - 0.16 9.8 13.6 0.17 9.6 9.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Plasmodium_Vir PF05795.6 AEO60645.1 - 0.21 10.7 2.7 0.27 10.4 1.9 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein zf-H2C2_2 PF13465.1 AEO60646.1 - 6.4e-09 35.6 17.8 2.3e-06 27.6 2.0 3.9 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 AEO60646.1 - 1.9e-07 30.9 14.9 0.0016 18.6 1.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AEO60646.1 - 5.3e-05 23.2 12.8 0.0055 16.9 1.0 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 AEO60646.1 - 1.5 9.0 4.9 1.7 8.8 0.8 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding AAA_25 PF13481.1 AEO60647.1 - 3.1e-08 33.2 0.0 8.4e-08 31.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain Rad51 PF08423.6 AEO60647.1 - 8.2e-06 24.9 0.0 3e-05 23.0 0.0 1.8 1 1 0 1 1 1 1 Rad51 KaiC PF06745.8 AEO60647.1 - 3.9e-05 22.8 0.0 8.4e-05 21.7 0.0 1.5 1 0 0 1 1 1 1 KaiC RecA PF00154.16 AEO60647.1 - 7.5e-05 21.9 0.1 0.00041 19.5 0.0 1.9 2 0 0 2 2 2 1 recA bacterial DNA recombination protein AAA_19 PF13245.1 AEO60647.1 - 8.5e-05 22.2 0.1 0.00022 20.9 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain DnaB_C PF03796.10 AEO60647.1 - 0.0001 21.2 0.1 0.0078 15.1 0.0 2.1 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_10 PF12846.2 AEO60647.1 - 0.061 12.7 0.1 0.13 11.6 0.0 1.5 2 0 0 2 2 2 0 AAA-like domain AAA_16 PF13191.1 AEO60647.1 - 0.076 12.9 0.3 0.37 10.7 0.2 2.2 1 1 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.12 AEO60647.1 - 0.096 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein PhoH PF02562.11 AEO60647.1 - 0.14 11.3 0.0 0.29 10.3 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Arch_ATPase PF01637.13 AEO60647.1 - 0.22 11.1 0.0 0.32 10.6 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase Bromodomain PF00439.20 AEO60649.1 - 4.6e-20 71.3 0.0 8.2e-20 70.5 0.0 1.3 1 0 0 1 1 1 1 Bromodomain BTB PF00651.26 AEO60649.1 - 0.00077 19.4 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain TIM21 PF08294.6 AEO60650.1 - 3.1e-46 156.6 0.1 4.1e-46 156.2 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.5 AEO60650.1 - 1.6e-08 34.0 0.0 3.9e-08 32.7 0.0 1.7 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 ArfGap PF01412.13 AEO60651.1 - 2.8e-36 123.8 0.5 5.1e-36 122.9 0.1 1.6 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf NDT80_PhoG PF05224.7 AEO60653.1 - 1e-45 156.0 3.6 1.5e-44 152.2 0.0 2.5 2 1 1 3 3 3 1 NDT80 / PhoG like DNA-binding family Neur_chan_memb PF02932.11 AEO60653.1 - 0.1 12.4 1.3 0.62 9.9 0.8 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region SelP_N PF04592.9 AEO60653.1 - 0.47 9.8 13.1 0.93 8.8 9.1 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.17 AEO60653.1 - 0.55 9.1 12.1 0.87 8.5 8.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4175 PF13779.1 AEO60653.1 - 2.9 5.4 13.1 4.3 4.9 9.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Pterin_bind PF00809.17 AEO60656.1 - 2.1e-59 200.4 0.0 6.6e-59 198.8 0.0 1.9 1 1 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 AEO60656.1 - 6.6e-40 135.7 0.0 1e-39 135.1 0.0 1.3 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) NMO PF03060.10 AEO60657.1 - 1.8e-73 247.5 0.4 2.5e-73 247.0 0.3 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 AEO60657.1 - 1.6e-10 40.4 0.5 3.3e-10 39.4 0.4 1.5 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 AEO60657.1 - 3e-07 29.6 2.2 4.5e-07 29.0 1.5 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 AEO60657.1 - 0.036 12.9 1.0 0.073 11.9 0.7 1.5 1 0 0 1 1 1 0 Conserved region in glutamate synthase Radial_spoke_3 PF06098.6 AEO60657.1 - 0.082 11.8 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Radial spoke protein 3 NanE PF04131.9 AEO60657.1 - 0.086 11.8 0.1 0.25 10.2 0.1 1.7 1 1 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase SUR7 PF06687.7 AEO60658.1 - 8.2e-13 48.4 0.1 1.2e-12 47.8 0.1 1.2 1 0 0 1 1 1 1 SUR7/PalI family ABC2_membrane_4 PF12730.2 AEO60658.1 - 0.00092 18.4 2.5 0.003 16.7 1.8 2.0 1 1 0 1 1 1 1 ABC-2 family transporter protein UbiA PF01040.13 AEO60658.1 - 0.0059 15.8 5.1 0.011 14.9 3.5 1.4 1 0 0 1 1 1 1 UbiA prenyltransferase family Yip1 PF04893.12 AEO60658.1 - 0.012 15.1 6.7 0.011 15.2 2.7 2.0 2 0 0 2 2 2 0 Yip1 domain HlyIII PF03006.15 AEO60658.1 - 0.036 13.4 4.6 0.065 12.6 3.2 1.3 1 0 0 1 1 1 0 Haemolysin-III related MscL PF01741.13 AEO60659.1 - 1.9e-15 57.1 0.3 5e-15 55.7 0.2 1.6 1 1 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL zf-BED PF02892.10 AEO60659.1 - 0.0001 21.9 1.2 0.00017 21.2 0.8 1.3 1 0 0 1 1 1 1 BED zinc finger C1_1 PF00130.17 AEO60659.1 - 0.016 14.9 1.2 0.026 14.2 0.8 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUP PF00674.13 AEO60659.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 DUP family PyrI_C PF02748.10 AEO60659.1 - 0.3 10.5 3.4 0.23 10.8 1.3 1.6 1 1 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Glyco_hydro_76 PF03663.9 AEO60662.1 - 1.7e-133 445.6 2.6 2e-133 445.3 1.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 DUF1680 PF07944.7 AEO60662.1 - 0.024 12.9 0.0 0.049 11.9 0.0 1.5 1 0 0 1 1 1 0 Putative glycosyl hydrolase of unknown function (DUF1680) Glyco_hydro_88 PF07470.8 AEO60662.1 - 0.65 8.9 4.7 13 4.6 0.1 3.1 1 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 Aminotran_1_2 PF00155.16 AEO60663.1 - 1.5e-64 218.2 0.0 1.8e-64 217.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Lipase_GDSL PF00657.17 AEO60664.1 - 4.4e-16 59.4 0.2 5.4e-16 59.1 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 AEO60664.1 - 3.7e-05 23.9 2.4 0.00037 20.6 1.6 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family RabGAP-TBC PF00566.13 AEO60666.1 - 1.3e-46 158.7 0.0 2.9e-46 157.6 0.0 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain IncA PF04156.9 AEO60666.1 - 0.0008 19.0 19.1 0.012 15.2 4.8 3.2 3 0 0 3 3 3 2 IncA protein ADIP PF11559.3 AEO60666.1 - 0.011 15.6 9.3 0.011 15.6 6.5 3.3 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding AAA_13 PF13166.1 AEO60666.1 - 0.028 12.9 7.1 0.048 12.1 4.9 1.3 1 0 0 1 1 1 0 AAA domain Laminin_II PF06009.7 AEO60666.1 - 0.044 13.5 8.1 0.038 13.7 1.5 2.7 2 0 0 2 2 2 0 Laminin Domain II DUF1664 PF07889.7 AEO60666.1 - 0.17 11.6 6.6 0.13 12.0 1.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.7 AEO60666.1 - 0.25 11.6 1.9 0.33 11.2 0.3 2.0 2 0 0 2 2 1 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.6 AEO60666.1 - 0.36 9.4 15.2 0.0082 14.8 3.4 2.7 3 0 0 3 3 3 0 Spc7 kinetochore protein TBPIP PF07106.8 AEO60666.1 - 0.82 9.1 13.0 0.25 10.8 1.5 3.1 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Syntaxin-6_N PF09177.6 AEO60666.1 - 1.1 9.7 12.1 1.2 9.5 2.9 3.5 3 1 0 3 3 3 0 Syntaxin 6, N-terminal APG6 PF04111.7 AEO60666.1 - 1.9 7.4 18.4 0.28 10.1 3.3 3.2 3 0 0 3 3 3 0 Autophagy protein Apg6 Fib_alpha PF08702.5 AEO60666.1 - 2.3 8.3 9.3 2.1 8.4 1.9 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF972 PF06156.8 AEO60666.1 - 2.5 8.5 15.2 0.087 13.1 0.5 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF972) HAUS6_N PF14661.1 AEO60666.1 - 9.6 5.4 13.9 1.1 8.6 4.1 2.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Reticulon PF02453.12 AEO60667.1 - 1.4e-40 138.6 4.8 2.2e-40 138.0 3.3 1.3 1 0 0 1 1 1 1 Reticulon DUF2547 PF10818.3 AEO60667.1 - 0.26 11.9 3.2 0.32 11.6 1.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2547) Wzy_C PF04932.10 AEO60667.1 - 3.7 7.3 8.5 50 3.6 5.3 2.3 1 1 0 1 1 1 0 O-Antigen ligase DNA_topoisoIV PF00521.15 AEO60668.1 - 5.4e-123 410.9 0.1 1.1e-122 410.0 0.1 1.5 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 AEO60668.1 - 5.3e-34 116.9 1.8 1.3e-33 115.6 1.2 1.7 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 AEO60668.1 - 2.8e-12 46.4 0.2 1.5e-11 44.1 0.0 2.3 2 0 0 2 2 2 1 Toprim domain HATPase_c PF02518.21 AEO60668.1 - 4.2e-10 39.3 0.0 1.1e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_11 PF13414.1 AEO60670.1 - 1.9e-08 33.8 9.5 0.0023 17.5 0.1 3.6 2 1 2 4 4 4 3 TPR repeat TPR_1 PF00515.23 AEO60670.1 - 4e-08 32.5 0.5 0.025 14.2 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 AEO60670.1 - 5.1e-05 22.8 11.7 0.06 13.2 0.1 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 AEO60670.1 - 0.015 15.6 2.4 0.015 15.6 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 AEO60670.1 - 0.015 15.9 0.6 0.015 15.9 0.4 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 AEO60670.1 - 0.023 14.5 0.9 2.2 8.2 0.0 2.7 1 1 1 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.1 AEO60670.1 - 0.13 12.4 0.5 0.52 10.6 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat CMV_1a PF12467.3 AEO60670.1 - 0.81 10.0 6.7 0.25 11.6 0.9 2.2 2 0 0 2 2 2 0 Cucumber mosaic virus 1a protein family Dynamin_N PF00350.18 AEO60671.1 - 2.3e-14 53.5 4.2 1.8e-13 50.6 0.0 3.4 1 1 1 2 2 1 1 Dynamin family MMR_HSR1 PF01926.18 AEO60671.1 - 0.00017 21.4 0.1 0.0086 16.0 0.0 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.22 AEO60671.1 - 0.0021 18.3 0.5 0.015 15.5 0.0 2.6 2 0 0 2 2 2 1 ABC transporter Miro PF08477.8 AEO60671.1 - 0.0023 18.3 0.0 0.018 15.5 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein IncA PF04156.9 AEO60671.1 - 0.0042 16.7 0.2 0.0042 16.7 0.2 2.7 3 0 0 3 3 2 2 IncA protein DUF4618 PF15397.1 AEO60671.1 - 0.0051 16.1 11.2 0.63 9.3 4.3 2.7 3 0 0 3 3 3 2 Domain of unknown function (DUF4618) DUF258 PF03193.11 AEO60671.1 - 0.0092 15.1 0.0 0.2 10.8 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 DUF4140 PF13600.1 AEO60671.1 - 0.011 16.1 10.0 1.4 9.4 0.1 3.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) AAA_22 PF13401.1 AEO60671.1 - 0.023 14.8 0.2 0.62 10.2 0.0 3.2 2 1 1 3 3 2 0 AAA domain NPV_P10 PF05531.7 AEO60671.1 - 0.032 14.4 1.5 5.1 7.4 0.0 2.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein AAA_17 PF13207.1 AEO60671.1 - 0.036 14.8 3.0 0.063 14.1 0.0 2.7 3 0 0 3 3 2 0 AAA domain SOBP PF15279.1 AEO60671.1 - 0.078 13.3 1.2 14 5.9 0.8 2.2 2 0 0 2 2 2 0 Sine oculis-binding protein AAA_16 PF13191.1 AEO60671.1 - 0.23 11.4 0.1 0.23 11.4 0.0 2.9 4 1 0 4 4 3 0 AAA ATPase domain V_ATPase_I PF01496.14 AEO60671.1 - 0.24 9.1 8.1 2.1 6.0 4.5 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF3713 PF12506.3 AEO60671.1 - 0.25 11.4 6.6 3.7 7.6 2.6 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3713) Vps51 PF08700.6 AEO60671.1 - 0.44 10.4 6.6 5.1 7.0 0.1 4.0 4 0 0 4 4 4 0 Vps51/Vps67 CENP-F_leu_zip PF10473.4 AEO60671.1 - 0.67 9.8 18.1 0.88 9.4 0.1 2.8 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.7 AEO60671.1 - 0.69 9.6 20.1 0.17 11.6 0.3 3.4 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.4 AEO60671.1 - 1.3 7.9 12.3 0.86 8.4 0.1 2.7 3 0 0 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1664 PF07889.7 AEO60671.1 - 1.3 8.8 5.2 14 5.4 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.5 AEO60671.1 - 1.9 8.5 10.1 8.5 6.4 0.0 3.5 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family DivIC PF04977.10 AEO60671.1 - 2.1 7.8 16.9 0.57 9.7 0.1 3.7 2 1 0 3 3 3 0 Septum formation initiator DUF972 PF06156.8 AEO60671.1 - 3.4 8.0 9.9 15 5.9 0.0 3.4 4 0 0 4 4 3 0 Protein of unknown function (DUF972) DUF2681 PF10883.3 AEO60671.1 - 4.3 7.5 8.0 6.4 7.0 3.8 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) Spectrin PF00435.16 AEO60671.1 - 7.9 6.8 19.3 2 8.7 0.1 4.2 4 1 1 5 5 4 0 Spectrin repeat TFIIB PF00382.14 AEO60672.1 - 0.0087 15.8 0.0 0.75 9.6 0.0 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Fungal_trans PF04082.13 AEO60673.1 - 2.1e-30 105.4 0.0 4.2e-30 104.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO60673.1 - 1.2e-08 34.7 8.6 1.9e-08 34.0 6.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 AEO60673.1 - 0.06 11.9 0.1 0.2 10.2 0.0 1.8 2 0 0 2 2 2 0 Fungal specific transcription factor domain DUF4306 PF14154.1 AEO60673.1 - 0.12 12.3 0.1 0.25 11.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4306) Pex14_N PF04695.8 AEO60675.1 - 0.061 13.3 0.3 0.087 12.8 0.2 1.5 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ACPS PF01648.15 AEO60676.1 - 0.00013 21.7 0.3 0.00029 20.6 0.0 1.7 2 1 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily ACPS PF01648.15 AEO60677.1 - 0.012 15.3 0.1 0.014 15.1 0.1 1.2 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase superfamily DUF1774 PF08611.5 AEO60678.1 - 7.8e-33 112.5 3.1 7.8e-33 112.5 2.1 2.2 3 0 0 3 3 3 1 Fungal protein of unknown function (DUF1774) DUF912 PF06024.7 AEO60678.1 - 9 6.4 0.0 9 6.4 0.0 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Clr5 PF14420.1 AEO60679.1 - 1.1e-13 50.8 1.5 2.1e-13 49.9 1.1 1.5 1 0 0 1 1 1 1 Clr5 domain PHP PF02811.14 AEO60680.1 - 3.1e-07 30.3 0.0 6.7e-07 29.2 0.0 1.5 1 1 0 1 1 1 1 PHP domain DHC_N1 PF08385.7 AEO60681.1 - 2.4e-194 647.0 2.5 2.4e-194 647.0 1.7 5.2 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 AEO60681.1 - 3.4e-131 437.5 9.3 3.4e-131 437.5 6.4 5.8 7 0 0 7 7 7 1 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 AEO60681.1 - 4.2e-106 355.6 0.0 4.2e-106 355.6 0.0 2.2 2 0 0 2 2 1 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 AEO60681.1 - 6.9e-77 258.0 0.0 1.8e-76 256.6 0.0 1.7 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 AEO60681.1 - 1.6e-43 148.1 0.1 4.9e-43 146.6 0.0 1.9 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 AEO60681.1 - 5.7e-41 140.2 0.6 9e-40 136.3 0.1 2.8 2 1 0 2 2 2 1 P-loop containing dynein motor region D4 MT PF12777.2 AEO60681.1 - 8.6e-41 139.8 10.3 8.6e-41 139.8 7.1 2.5 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 AEO60681.1 - 9.9e-32 109.5 0.0 6.3e-12 45.4 0.0 6.0 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 AEO60681.1 - 1.6e-21 76.5 0.0 2.8e-20 72.5 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 AEO60681.1 - 1.8e-16 60.4 0.1 0.015 15.4 0.0 7.1 6 1 0 6 6 5 3 AAA domain AAA PF00004.24 AEO60681.1 - 2.8e-13 50.2 0.0 0.0019 18.3 0.0 4.8 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 AEO60681.1 - 6.4e-10 39.0 0.3 0.36 10.7 0.0 5.5 4 0 0 4 4 4 3 AAA domain AAA_17 PF13207.1 AEO60681.1 - 1.9e-09 38.3 3.5 0.031 15.1 0.0 6.1 6 0 0 6 6 4 2 AAA domain AAA_16 PF13191.1 AEO60681.1 - 1.1e-08 35.3 15.9 0.11 12.4 0.0 8.7 7 1 1 8 8 8 2 AAA ATPase domain AAA_18 PF13238.1 AEO60681.1 - 2.4e-08 34.3 2.3 0.024 14.9 0.0 5.7 6 0 0 6 6 5 2 AAA domain AAA_14 PF13173.1 AEO60681.1 - 8.4e-07 28.9 0.0 0.21 11.4 0.0 5.6 5 0 0 5 5 4 1 AAA domain T2SE PF00437.15 AEO60681.1 - 9.9e-07 27.9 0.0 0.051 12.4 0.0 3.8 4 0 0 4 4 4 2 Type II/IV secretion system protein AAA_29 PF13555.1 AEO60681.1 - 2e-06 27.2 0.0 0.3 10.6 0.0 3.6 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_19 PF13245.1 AEO60681.1 - 1.5e-05 24.6 0.1 0.89 9.3 0.0 4.8 5 0 0 5 5 5 1 Part of AAA domain Mg_chelatase PF01078.16 AEO60681.1 - 3.9e-05 22.9 0.5 0.5 9.4 0.0 4.0 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 AEO60681.1 - 0.00019 21.7 0.1 3.9 7.7 0.0 4.6 3 0 0 3 3 3 1 ABC transporter RNA_helicase PF00910.17 AEO60681.1 - 0.0086 16.2 0.0 36 4.5 0.0 4.9 5 0 0 5 5 4 0 RNA helicase MobB PF03205.9 AEO60681.1 - 0.034 13.8 0.1 12 5.5 0.0 3.4 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 AEO60681.1 - 0.055 12.8 5.4 0.31 10.4 0.0 4.2 4 0 0 4 4 4 0 AAA domain ERM PF00769.14 AEO60681.1 - 7 6.1 38.8 0.88 9.0 3.1 3.4 3 0 0 3 3 2 0 Ezrin/radixin/moesin family ACCA PF03255.9 AEO60682.1 - 9.8 5.7 10.5 13 5.3 1.5 2.4 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Spc97_Spc98 PF04130.8 AEO60683.1 - 1.8e-66 224.5 0.0 2.9e-66 223.9 0.0 1.3 1 1 0 1 1 1 1 Spc97 / Spc98 family CDC45 PF02724.9 AEO60683.1 - 0.023 12.7 0.0 0.032 12.2 0.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Senescence PF06911.7 AEO60684.1 - 5e-49 166.4 0.9 7.9e-49 165.7 0.7 1.3 1 0 0 1 1 1 1 Senescence-associated protein Fungal_trans PF04082.13 AEO60685.1 - 3.4e-20 72.0 0.0 1.2e-19 70.2 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO60685.1 - 1.6e-09 37.5 8.9 2.7e-09 36.7 6.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CDK5_activator PF03261.10 AEO60685.1 - 0.12 11.7 8.3 0.2 10.9 5.7 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein SelP_N PF04592.9 AEO60685.1 - 5.2 6.3 26.8 9 5.5 18.6 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.17 AEO60685.1 - 5.3 5.9 14.8 8.9 5.2 10.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter CENP-U PF13097.1 AEO60686.1 - 0.043 13.7 2.0 0.047 13.6 1.4 1.0 1 0 0 1 1 1 0 CENP-A nucleosome associated complex (NAC) subunit DUF1117 PF06547.7 AEO60686.1 - 0.082 13.0 7.0 0.11 12.6 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1117) SR-25 PF10500.4 AEO60686.1 - 0.18 11.2 22.7 0.43 9.9 9.2 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Actino_peptide PF14408.1 AEO60686.1 - 0.58 10.1 0.1 0.58 10.1 0.0 2.1 2 0 0 2 2 2 0 Ribosomally synthesized peptide in actinomycetes Herpes_capsid PF06112.6 AEO60686.1 - 4.1 7.4 13.6 4.5 7.3 9.4 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein SSP160 PF06933.6 AEO60686.1 - 4.6 5.0 13.6 5.2 4.9 9.4 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF221 PF02714.10 AEO60687.1 - 3.5e-109 364.5 26.2 3.5e-109 364.5 18.2 2.0 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 AEO60687.1 - 1e-44 151.8 0.4 1e-44 151.8 0.3 3.4 4 1 0 4 4 4 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 AEO60687.1 - 4e-31 106.7 0.1 1.1e-30 105.3 0.0 1.7 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 AEO60687.1 - 5.8e-24 84.4 0.9 1.2e-23 83.3 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Colicin_V PF02674.11 AEO60687.1 - 0.33 10.8 19.5 0.016 15.0 5.1 3.1 1 1 0 2 2 2 0 Colicin V production protein Cep57_CLD_2 PF14197.1 AEO60688.1 - 0.012 15.5 0.3 0.012 15.5 0.2 1.9 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Nucleoplasmin PF03066.10 AEO60688.1 - 0.021 14.3 4.4 0.034 13.6 3.0 1.3 1 0 0 1 1 1 0 Nucleoplasmin bZIP_1 PF00170.16 AEO60688.1 - 0.049 13.5 1.1 0.14 12.1 0.7 1.7 1 1 0 1 1 1 0 bZIP transcription factor RXT2_N PF08595.6 AEO60688.1 - 0.16 11.7 2.2 0.32 10.7 1.5 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal UL73_N PF12522.3 AEO60688.1 - 0.23 11.0 9.0 0.44 10.1 6.2 1.5 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein N terminal CENP-B_dimeris PF09026.5 AEO60688.1 - 0.26 11.5 10.4 4.4 7.6 7.2 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Sigma70_ner PF04546.8 AEO60688.1 - 1.1 8.8 6.0 0.12 11.9 0.8 1.7 2 0 0 2 2 2 0 Sigma-70, non-essential region SKG6 PF08693.5 AEO60689.1 - 0.00031 19.9 0.4 0.0008 18.6 0.3 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain SR-25 PF10500.4 AEO60689.1 - 0.00044 19.8 8.6 0.00044 19.8 6.0 3.3 4 0 0 4 4 4 1 Nuclear RNA-splicing-associated protein Kelch_4 PF13418.1 AEO60689.1 - 0.00055 19.6 11.7 1.6 8.5 1.3 5.7 5 1 0 5 5 5 2 Galactose oxidase, central domain DUF347 PF03988.7 AEO60689.1 - 0.0043 16.9 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 Repeat of Unknown Function (DUF347) MLANA PF14991.1 AEO60689.1 - 0.096 12.7 0.0 0.31 11.0 0.0 1.8 1 0 0 1 1 1 0 Protein melan-A Cwf_Cwc_15 PF04889.7 AEO60689.1 - 0.69 9.5 10.0 0.037 13.7 2.3 2.0 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Herpes_gE PF02480.11 AEO60689.1 - 0.95 7.6 0.0 0.95 7.6 0.0 2.2 3 0 0 3 3 3 0 Alphaherpesvirus glycoprotein E CDC45 PF02724.9 AEO60689.1 - 8.9 4.2 10.5 14 3.5 7.3 1.2 1 0 0 1 1 1 0 CDC45-like protein WSC PF01822.14 AEO60690.1 - 9.1e-13 47.9 7.2 1.8e-12 46.9 5.0 1.5 1 0 0 1 1 1 1 WSC domain Herpes_gE PF02480.11 AEO60690.1 - 0.039 12.2 0.0 0.052 11.8 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Adeno_E3_CR2 PF02439.10 AEO60690.1 - 0.16 11.5 0.1 0.31 10.6 0.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SKG6 PF08693.5 AEO60690.1 - 0.23 10.8 4.0 0.52 9.6 2.8 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Tho2 PF11262.3 AEO60691.1 - 4.7e-89 298.3 0.2 6.6e-89 297.8 0.1 1.2 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 AEO60691.1 - 4.8e-29 99.9 0.2 9.1e-29 99.0 0.1 1.5 1 0 0 1 1 1 1 Transcription- and export-related complex subunit Abhydrolase_1 PF00561.15 AEO60692.1 - 3.6e-43 147.7 0.0 8.3e-40 136.7 0.0 2.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 AEO60692.1 - 4.2e-11 43.1 2.0 3.4e-10 40.1 1.4 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO60692.1 - 0.0076 16.0 0.1 0.093 12.4 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 AEO60692.1 - 0.023 14.5 0.0 0.054 13.3 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein Esterase PF00756.15 AEO60692.1 - 0.055 12.8 0.1 0.14 11.5 0.1 1.6 2 0 0 2 2 2 0 Putative esterase Methyltransf_23 PF13489.1 AEO60693.1 - 5.4e-22 78.2 0.0 7.8e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO60693.1 - 1.4e-10 41.0 0.0 5.3e-10 39.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO60693.1 - 5.4e-10 39.6 0.0 8.4e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO60693.1 - 2e-09 38.0 0.0 2.2e-08 34.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO60693.1 - 4.2e-07 30.3 0.0 1.8e-06 28.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO60693.1 - 1.6e-06 28.4 0.0 3e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 AEO60693.1 - 0.0019 17.2 0.0 0.0048 15.9 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 AEO60693.1 - 0.0056 16.0 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain CheR PF01739.13 AEO60693.1 - 0.0083 15.4 0.0 0.024 13.9 0.0 1.6 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain PrmA PF06325.8 AEO60693.1 - 0.0094 15.1 0.0 0.019 14.1 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.4 AEO60693.1 - 0.0099 15.3 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.15 AEO60693.1 - 0.023 13.7 0.0 0.04 12.9 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase GidB PF02527.10 AEO60693.1 - 0.033 13.3 0.0 0.1 11.7 0.0 1.9 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_26 PF13659.1 AEO60693.1 - 0.058 13.4 0.0 0.13 12.2 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.7 AEO60693.1 - 0.095 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_2 PF00891.13 AEO60693.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase DSPc PF00782.15 AEO60694.1 - 3.5e-12 46.0 0.0 3.3e-11 42.8 0.0 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain DUF2360 PF10152.4 AEO60694.1 - 0.13 12.5 0.3 0.27 11.5 0.0 1.6 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Spo7 PF03907.8 AEO60695.1 - 3.5e-69 232.5 0.1 4.5e-69 232.2 0.0 1.1 1 0 0 1 1 1 1 Spo7-like protein Abhydrolase_6 PF12697.2 AEO60696.1 - 3.5e-29 102.2 1.4 1.1e-28 100.7 0.1 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO60696.1 - 2.2e-15 56.8 0.0 1.8e-14 53.8 0.0 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AEO60696.1 - 8.7e-13 48.2 0.0 4.3e-11 42.7 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 AEO60696.1 - 3.9e-05 22.8 0.0 7.8e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.15 AEO60696.1 - 0.00011 21.7 0.0 0.00023 20.6 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.15 AEO60696.1 - 0.00072 19.8 0.3 0.0059 16.8 0.0 2.5 2 1 0 2 2 2 1 Thioesterase domain Abhydrolase_2 PF02230.11 AEO60696.1 - 0.009 15.4 0.0 2.9 7.2 0.0 2.7 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.3 AEO60696.1 - 0.023 14.5 0.0 0.061 13.1 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase Lipase_3 PF01764.20 AEO60696.1 - 0.023 14.3 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_3 PF07859.8 AEO60696.1 - 0.054 13.0 0.0 0.24 10.9 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 AEO60696.1 - 0.12 11.1 0.0 0.24 10.2 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF2305 PF10230.4 AEO60696.1 - 0.16 11.3 0.0 0.45 9.8 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) DUF3698 PF12479.3 AEO60696.1 - 0.2 11.7 0.1 0.48 10.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3698) Hist_deacetyl PF00850.14 AEO60697.1 - 1.5e-61 208.3 0.1 2.2e-61 207.8 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain TGT PF01702.13 AEO60700.1 - 5e-88 294.3 0.0 5.8e-88 294.1 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Mit_ribos_Mrp51 PF11709.3 AEO60701.1 - 8.4e-99 330.7 0.1 1e-98 330.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit Ribosomal_S17e PF00833.13 AEO60702.1 - 3.1e-59 198.0 0.4 3.8e-59 197.8 0.3 1.0 1 0 0 1 1 1 1 Ribosomal S17 Cryptochrome_C PF12546.3 AEO60702.1 - 0.087 13.5 0.0 0.12 13.0 0.0 1.2 1 0 0 1 1 1 0 Blue/Ultraviolet sensing protein C terminal RPAP2_Rtr1 PF04181.8 AEO60703.1 - 5.8e-19 67.9 0.1 9.2e-19 67.3 0.1 1.3 1 0 0 1 1 1 1 Rtr1/RPAP2 family SH3_1 PF00018.23 AEO60704.1 - 6.9e-12 44.5 0.3 2.1e-11 42.9 0.2 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 AEO60704.1 - 1.8e-10 40.2 0.2 5.2e-10 38.7 0.2 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 AEO60704.1 - 8.9e-09 34.7 0.1 1e-07 31.3 0.1 2.1 2 0 0 2 2 2 1 Variant SH3 domain Acyl_transf_1 PF00698.16 AEO60708.1 - 2.2e-81 273.6 0.0 1.9e-78 264.0 0.0 3.8 4 0 0 4 4 4 1 Acyl transferase domain MaoC_dehydratas PF01575.14 AEO60708.1 - 1.3e-37 127.8 0.8 2.1e-37 127.2 0.1 1.7 2 0 0 2 2 2 1 MaoC like domain DUF1729 PF08354.5 AEO60708.1 - 3.8e-31 106.6 0.1 1.9e-30 104.3 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 AEO60708.1 - 4.2e-23 81.5 0.2 2.8e-22 78.9 0.0 2.5 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase NMO PF03060.10 AEO60708.1 - 0.0017 17.5 0.1 0.38 9.8 0.1 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase PBP_GOBP PF01395.17 AEO60708.1 - 0.2 11.3 0.1 0.39 10.3 0.1 1.4 1 0 0 1 1 1 0 PBP/GOBP family ketoacyl-synt PF00109.21 AEO60709.1 - 1e-22 80.8 0.1 2.3e-22 79.7 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.1 AEO60709.1 - 1e-20 74.5 0.8 1.7e-19 70.5 0.0 3.0 4 0 0 4 4 4 1 Enoyl-(Acyl carrier protein) reductase ACPS PF01648.15 AEO60709.1 - 3.6e-17 62.2 0.0 8.1e-17 61.0 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 AEO60709.1 - 8.8e-11 41.6 1.7 2.7e-10 40.1 0.0 2.6 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 AEO60709.1 - 1.2e-06 28.5 0.0 7.1e-06 26.0 0.0 2.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO60709.1 - 0.0032 17.1 0.5 0.013 15.2 0.0 2.3 2 0 0 2 2 2 1 KR domain DUF1031 PF06275.6 AEO60709.1 - 0.084 12.9 0.2 6.8 6.8 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1031) Amidohydro_1 PF01979.15 AEO60710.1 - 1.8e-36 126.4 0.0 2.3e-36 126.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 AEO60710.1 - 1.6e-06 27.8 0.0 4.5e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 AEO60710.1 - 6.7e-05 23.0 4.4 0.047 13.7 1.9 2.3 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 AEO60710.1 - 0.039 13.1 8.3 0.095 11.9 0.7 2.6 2 2 0 2 2 2 0 Amidohydrolase family AAA PF00004.24 AEO60712.1 - 3.6e-11 43.3 0.0 7e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AEO60712.1 - 2.9e-05 24.2 0.0 8.2e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 AEO60712.1 - 6.5e-05 22.0 0.0 0.00013 21.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 AEO60712.1 - 0.00017 21.2 0.1 0.00076 19.1 0.0 2.2 2 0 0 2 2 1 1 Part of AAA domain AAA_33 PF13671.1 AEO60712.1 - 0.00018 21.3 0.0 0.00058 19.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 AEO60712.1 - 0.00078 19.1 0.0 0.0016 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 AEO60712.1 - 0.0017 18.2 0.0 0.003 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AEO60712.1 - 0.0051 17.6 0.0 0.016 15.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AEO60712.1 - 0.0059 16.6 0.6 0.037 14.0 0.0 2.3 2 1 1 3 3 3 1 AAA ATPase domain Rad17 PF03215.10 AEO60712.1 - 0.0076 14.9 0.0 0.012 14.3 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein Zeta_toxin PF06414.7 AEO60712.1 - 0.019 14.0 0.0 0.061 12.4 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin NB-ARC PF00931.17 AEO60712.1 - 0.022 13.6 0.0 0.035 12.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_28 PF13521.1 AEO60712.1 - 0.031 14.2 0.1 0.34 10.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 AEO60712.1 - 0.034 13.3 0.0 0.061 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 AEO60712.1 - 0.15 11.4 0.0 0.3 10.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ABC_tran PF00005.22 AEO60712.1 - 0.15 12.3 0.2 0.46 10.7 0.0 1.9 2 0 0 2 2 1 0 ABC transporter Arch_ATPase PF01637.13 AEO60712.1 - 0.37 10.4 0.0 0.95 9.1 0.0 1.6 1 1 1 2 2 2 0 Archaeal ATPase Sulfate_transp PF00916.15 AEO60713.1 - 2.5e-83 279.3 6.0 3.7e-83 278.7 4.1 1.3 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 AEO60713.1 - 1.2e-29 101.7 3.3 1.2e-29 101.7 2.3 3.0 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 AEO60713.1 - 2.9e-08 33.1 0.0 5.3e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 AEO60713.1 - 0.018 15.0 0.5 0.057 13.4 0.3 1.8 1 0 0 1 1 1 0 STAS domain HLH PF00010.21 AEO60714.1 - 2e-08 33.7 0.0 4e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Herpes_UL6 PF01763.11 AEO60714.1 - 0.069 11.3 0.0 0.099 10.8 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Pox_A_type_inc PF04508.7 AEO60714.1 - 0.11 12.3 0.2 0.39 10.6 0.2 1.9 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat APH PF01636.18 AEO60715.1 - 1.2e-06 28.4 0.1 0.0028 17.4 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.20 AEO60715.1 - 5.7e-05 22.4 0.0 8.3e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.15 AEO60715.1 - 0.00024 20.7 0.0 0.00071 19.2 0.0 1.6 1 1 1 2 2 2 1 Choline/ethanolamine kinase RIO1 PF01163.17 AEO60715.1 - 0.005 16.2 0.0 0.0087 15.4 0.0 1.3 1 1 0 1 1 1 1 RIO1 family Kdo PF06293.9 AEO60715.1 - 0.012 14.6 0.1 0.66 8.9 0.1 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1772 PF08592.6 AEO60716.1 - 1 9.1 4.3 1.9 8.2 3.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) Pkinase PF00069.20 AEO60717.1 - 4.5e-17 62.0 0.0 6.5e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO60717.1 - 0.0014 17.8 0.0 0.0019 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO60717.1 - 0.048 12.6 0.0 0.063 12.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like SNF2_N PF00176.18 AEO60718.1 - 7.1e-20 70.9 0.0 8.2e-18 64.2 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 AEO60718.1 - 7.1e-09 35.4 0.0 3.4e-08 33.2 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DUF2318 PF10080.4 AEO60718.1 - 0.004 16.8 1.7 0.0094 15.7 1.1 1.5 1 0 0 1 1 1 1 Predicted membrane protein (DUF2318) zf-C3HC4 PF00097.20 AEO60718.1 - 0.0048 16.5 4.0 0.011 15.4 2.7 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 AEO60718.1 - 0.0049 16.5 0.3 0.014 15.0 0.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 AEO60718.1 - 0.0073 16.1 2.6 0.0073 16.1 1.8 1.7 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 AEO60718.1 - 0.013 15.1 4.1 0.025 14.2 2.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AEO60718.1 - 0.016 15.1 5.4 0.016 15.1 3.7 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO60718.1 - 0.11 12.2 5.3 0.27 10.9 3.7 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.1 AEO60718.1 - 0.19 11.5 4.7 0.41 10.5 3.3 1.6 1 0 0 1 1 1 0 Ring finger domain NmrA PF05368.8 AEO60720.1 - 5.5e-08 32.3 0.1 1.2e-07 31.2 0.1 1.7 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 AEO60720.1 - 0.03 14.3 0.2 0.088 12.8 0.2 1.7 1 1 0 1 1 1 0 NADH(P)-binding Ank_2 PF12796.2 AEO60721.1 - 5.6e-61 202.8 25.8 2.7e-08 34.0 0.0 14.6 7 4 4 12 12 12 11 Ankyrin repeats (3 copies) Ank PF00023.25 AEO60721.1 - 2.3e-23 80.7 50.8 0.041 13.7 0.0 21.8 26 2 0 26 26 26 8 Ankyrin repeat Ank_4 PF13637.1 AEO60721.1 - 7.4e-23 80.4 11.5 0.002 18.5 0.0 14.4 13 3 1 14 14 14 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 AEO60721.1 - 6.9e-19 66.0 12.7 3.4 8.2 0.0 19.5 23 1 0 23 23 23 4 Ankyrin repeat Ank_5 PF13857.1 AEO60721.1 - 1.2e-14 54.0 26.8 0.17 12.2 0.0 15.5 15 3 2 17 17 17 4 Ankyrin repeats (many copies) HET PF06985.6 AEO60722.1 - 0.0001 22.4 0.2 0.0032 17.6 0.0 2.3 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF755 PF05501.6 AEO60722.1 - 3.2 7.8 10.3 5 7.1 7.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) SR-25 PF10500.4 AEO60722.1 - 8.7 5.7 12.2 17 4.8 8.4 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ADH_zinc_N PF00107.21 AEO60723.1 - 1e-28 99.5 1.5 1.9e-28 98.6 1.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 AEO60723.1 - 2.2e-17 64.1 1.5 2.5e-17 63.9 0.2 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 AEO60723.1 - 2.4e-07 30.4 0.0 4.4e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.16 AEO60724.1 - 1.7e-46 158.6 0.0 2.2e-46 158.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 AEO60724.1 - 4.5e-25 87.3 0.0 7.8e-25 86.5 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 AEO60724.1 - 1.5e-15 56.6 0.1 3e-15 55.6 0.0 1.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 AEO60724.1 - 4e-14 52.1 0.0 6.1e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 AEO60724.1 - 4.6e-14 52.0 0.1 9.7e-11 41.0 0.0 2.5 2 1 1 3 3 3 2 Polysaccharide biosynthesis protein adh_short PF00106.20 AEO60724.1 - 2.8e-12 46.8 0.0 4.5e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 AEO60724.1 - 1.2e-09 37.4 0.0 1.3e-08 34.0 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 AEO60724.1 - 1.8e-08 34.6 0.0 3.4e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 AEO60724.1 - 2.9e-08 33.5 0.0 5.9e-08 32.5 0.0 1.4 1 1 0 1 1 1 1 KR domain UDPG_MGDP_dh_N PF03721.9 AEO60724.1 - 0.0055 16.1 0.2 0.0097 15.2 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NmrA PF05368.8 AEO60724.1 - 0.0076 15.5 0.0 0.033 13.4 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family Saccharop_dh PF03435.13 AEO60724.1 - 0.0079 15.2 0.1 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Methyltransf_18 PF12847.2 AEO60724.1 - 0.027 15.0 0.0 3.4 8.2 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Thrombin_light PF09396.5 AEO60724.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Thrombin light chain Sad1_UNC PF07738.8 AEO60725.1 - 1.7e-09 37.5 0.0 0.00054 19.7 0.0 2.4 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal Daxx PF03344.10 AEO60725.1 - 0.45 8.9 23.8 0.76 8.1 16.5 1.3 1 0 0 1 1 1 0 Daxx Family PAT1 PF09770.4 AEO60725.1 - 1.9 6.6 34.5 3.2 5.8 23.9 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DEAD PF00270.24 AEO60726.1 - 1.4e-43 148.3 0.0 2.7e-43 147.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 AEO60726.1 - 8.8e-24 82.8 0.1 1.9e-23 81.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 AEO60726.1 - 1e-21 76.5 0.0 2e-21 75.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Transp_cyt_pur PF02133.10 AEO60727.1 - 1.9e-150 501.2 32.4 2.2e-150 501.0 22.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin OPT PF03169.10 AEO60728.1 - 1.1e-95 321.3 34.8 4.9e-59 200.3 13.0 2.0 1 1 1 2 2 2 2 OPT oligopeptide transporter protein TFIIF_alpha PF05793.7 AEO60729.1 - 8.6 4.5 5.7 12 4.0 3.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Zip PF02535.17 AEO60731.1 - 0.036 13.0 1.7 0.045 12.7 1.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Utp21 PF04192.7 AEO60731.1 - 0.51 9.4 4.2 0.68 8.9 2.9 1.1 1 0 0 1 1 1 0 Utp21 specific WD40 associated putative domain TFIIA PF03153.8 AEO60731.1 - 1.8 8.3 7.7 2.1 8.1 5.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAP1 PF08601.5 AEO60731.1 - 2.6 7.6 8.3 2.9 7.4 5.8 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Med13_C PF06333.7 AEO60731.1 - 3.5 6.0 5.6 4 5.8 3.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal Senescence_reg PF04520.8 AEO60731.1 - 8.2 6.9 9.5 13 6.2 6.5 1.5 1 1 0 1 1 1 0 Senescence regulator DIE2_ALG10 PF04922.7 AEO60732.1 - 2.8e-81 273.4 13.7 4.2e-81 272.8 9.5 1.3 1 0 0 1 1 1 1 DIE2/ALG10 family QCR10 PF09796.4 AEO60733.1 - 8.8e-26 89.3 0.1 1.1e-25 89.0 0.1 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) UCR_6-4kD PF08997.5 AEO60733.1 - 0.0061 16.2 0.0 0.015 15.0 0.0 1.6 1 1 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex, 6.4kD protein Med4 PF10018.4 AEO60734.1 - 7e-55 185.3 9.5 9.4e-55 184.9 6.6 1.2 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 PAT1 PF09770.4 AEO60734.1 - 0.0062 14.8 14.3 0.0075 14.5 9.9 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Acylphosphatase PF00708.13 AEO60734.1 - 0.067 13.3 0.1 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Acylphosphatase ARGLU PF15346.1 AEO60734.1 - 0.32 10.7 25.5 0.12 12.1 14.1 2.1 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 MAP7 PF05672.6 AEO60734.1 - 3.8 6.8 35.1 0.099 12.0 18.1 2.4 2 1 1 3 3 3 0 MAP7 (E-MAP-115) family Caldesmon PF02029.10 AEO60734.1 - 5.2 5.3 22.8 0.39 9.0 12.5 1.4 2 0 0 2 2 2 0 Caldesmon DUF1509 PF07420.6 AEO60734.1 - 6 6.0 17.1 8.2 5.5 11.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) EMP70 PF02990.11 AEO60735.1 - 2.5e-193 643.3 5.8 3.1e-193 642.9 4.0 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 NfeD PF01957.13 AEO60735.1 - 0.074 13.1 0.0 0.074 13.1 0.0 4.6 3 2 1 5 5 5 0 NfeD-like C-terminal, partner-binding GP41 PF00517.12 AEO60735.1 - 7.7 6.0 7.1 2.3 7.7 0.1 2.6 2 0 0 2 2 2 0 Retroviral envelope protein Sas10_Utp3 PF04000.10 AEO60736.1 - 1.3e-15 57.2 3.6 3.2e-15 56.0 2.5 1.6 1 0 0 1 1 1 1 Sas10/Utp3/C1D family CDV3 PF15359.1 AEO60736.1 - 4.5 7.3 9.7 0.87 9.6 3.6 2.2 2 1 0 2 2 2 0 Carnitine deficiency-associated protein 3 Pyr_redox_3 PF13738.1 AEO60737.1 - 7.2e-20 71.9 0.0 4.1e-19 69.4 0.0 2.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 AEO60737.1 - 8.7e-18 63.8 0.0 9.2e-11 40.6 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 AEO60737.1 - 5e-10 39.5 0.1 0.001 19.0 0.0 2.7 2 2 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 AEO60737.1 - 1.2e-07 31.0 0.0 9e-06 24.8 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 AEO60737.1 - 1.3e-07 31.4 1.7 9.4e-07 28.7 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 AEO60737.1 - 8.4e-07 28.2 1.8 1.6e-06 27.2 0.1 2.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 AEO60737.1 - 3.5e-06 27.3 3.6 0.017 15.4 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 AEO60737.1 - 1.2e-05 25.4 0.1 0.0029 17.7 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 AEO60737.1 - 0.0021 17.7 0.1 0.0035 17.0 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 AEO60737.1 - 0.011 15.4 5.1 0.093 12.5 0.9 3.6 3 1 0 3 3 3 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 AEO60737.1 - 0.011 15.9 0.0 0.7 10.1 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 AEO60737.1 - 0.029 13.9 0.2 4.1 6.9 0.0 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 AEO60737.1 - 0.07 11.5 2.4 0.39 9.1 0.3 2.2 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.19 AEO60737.1 - 0.099 11.4 5.6 0.11 11.3 1.1 2.1 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.17 AEO60737.1 - 2.6 6.8 3.6 2.6 6.8 0.5 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Chitin_bind_1 PF00187.14 AEO60738.1 - 1.1e-07 31.7 15.4 1.1e-07 31.7 10.7 2.5 2 0 0 2 2 2 1 Chitin recognition protein BAMBI PF06211.7 AEO60738.1 - 2.1 8.3 7.6 0.87 9.6 3.8 1.5 1 1 0 1 1 1 0 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain BTB PF00651.26 AEO60740.1 - 0.00015 21.6 0.0 0.00039 20.3 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain KGG PF10685.4 AEO60741.1 - 7.5e-29 99.0 20.5 2.6e-13 49.5 1.8 3.1 3 0 0 3 3 3 3 Stress-induced bacterial acidophilic repeat motif LEA_5 PF00477.12 AEO60741.1 - 0.13 12.5 3.1 0.25 11.6 2.1 1.5 1 1 0 1 1 1 0 Small hydrophilic plant seed protein Pkinase PF00069.20 AEO60742.1 - 1.1e-06 28.0 0.0 2.1e-06 27.0 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.18 AEO60742.1 - 3.1e-05 23.8 0.4 0.00016 21.4 0.0 2.1 2 1 0 3 3 3 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 AEO60742.1 - 0.03 13.3 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase RIO1 PF01163.17 AEO60742.1 - 0.049 12.9 0.0 0.083 12.2 0.0 1.4 1 0 0 1 1 1 0 RIO1 family FlgN PF05130.7 AEO60743.1 - 0.0051 17.0 1.4 0.0081 16.4 1.0 1.4 1 0 0 1 1 1 1 FlgN protein APG6 PF04111.7 AEO60743.1 - 0.0056 15.7 0.5 0.0069 15.4 0.3 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 OmpH PF03938.9 AEO60743.1 - 0.036 13.9 0.4 0.047 13.6 0.3 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1599 PF07659.6 AEO60743.1 - 0.086 12.9 2.6 5.7 7.0 0.1 2.3 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1599) DUF1664 PF07889.7 AEO60743.1 - 0.15 11.8 0.3 0.23 11.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Fzo_mitofusin PF04799.8 AEO60743.1 - 0.2 11.0 1.1 0.29 10.5 0.8 1.2 1 0 0 1 1 1 0 fzo-like conserved region DUF724 PF05266.9 AEO60743.1 - 0.22 11.1 3.0 0.61 9.6 2.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF724) CALCOCO1 PF07888.6 AEO60743.1 - 1.5 7.0 9.3 1.9 6.7 6.5 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2852 PF11014.3 AEO60743.1 - 2.5 8.0 6.2 2.6 8.0 3.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) DUF900 PF05990.7 AEO60744.1 - 0.00043 19.6 0.0 0.0007 18.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Host_attach PF10116.4 AEO60744.1 - 0.0057 16.8 0.2 0.012 15.8 0.2 1.5 1 0 0 1 1 1 1 Protein required for attachment to host cells Pkinase_Tyr PF07714.12 AEO60745.1 - 2.2e-16 59.7 0.0 1.2e-15 57.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 AEO60745.1 - 1.1e-13 50.9 0.0 2e-13 50.1 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 AEO60745.1 - 0.0029 16.6 0.0 0.0043 16.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 AEO60745.1 - 0.0053 15.7 0.0 0.0085 15.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 AEO60745.1 - 0.041 13.6 0.6 0.073 12.7 0.4 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF3650 PF12368.3 AEO60745.1 - 0.069 12.6 0.1 0.14 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3650) zf-RING_2 PF13639.1 AEO60746.1 - 8.3e-14 51.1 7.2 9.9e-14 50.9 5.0 1.1 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 AEO60746.1 - 8e-10 38.5 5.4 9.9e-10 38.2 3.8 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AEO60746.1 - 1e-08 34.6 4.5 1.3e-08 34.3 3.1 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO60746.1 - 8.8e-07 28.5 4.0 1e-06 28.3 2.8 1.1 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 AEO60746.1 - 3.4e-06 27.0 8.1 4.7e-06 26.6 5.6 1.3 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 AEO60746.1 - 9.1e-06 25.2 3.3 1e-05 25.0 2.3 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 AEO60746.1 - 3.3e-05 23.6 2.4 4e-05 23.3 1.7 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 AEO60746.1 - 0.00024 21.0 4.1 0.00034 20.6 2.8 1.2 1 0 0 1 1 1 1 RING-variant domain zf-RING_UBOX PF13445.1 AEO60746.1 - 0.0016 18.0 3.4 0.0023 17.5 0.9 2.0 1 1 1 2 2 2 1 RING-type zinc-finger FANCL_C PF11793.3 AEO60746.1 - 0.0073 16.2 4.7 0.082 12.8 1.0 2.2 1 1 1 2 2 2 1 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 AEO60746.1 - 0.036 13.9 4.2 0.078 12.8 3.0 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING TGF_beta_GS PF08515.7 AEO60746.1 - 0.072 12.4 1.0 0.11 11.8 0.7 1.3 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif zf-Nse PF11789.3 AEO60746.1 - 0.14 11.7 3.6 0.16 11.4 2.5 1.1 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF4206 PF13901.1 AEO60746.1 - 0.16 11.4 2.2 0.2 11.2 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) zf-RING-like PF08746.6 AEO60746.1 - 0.22 11.5 5.5 0.3 11.1 3.8 1.2 1 0 0 1 1 1 0 RING-like domain Prok-RING_4 PF14447.1 AEO60746.1 - 0.8 9.3 5.6 1.5 8.4 3.9 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 E1-E2_ATPase PF00122.15 AEO60747.1 - 2.9e-56 190.0 0.3 2.9e-56 190.0 0.2 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 AEO60747.1 - 3.4e-39 134.2 8.4 3.4e-39 134.2 5.8 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 AEO60747.1 - 8e-27 95.0 0.0 3.3e-26 93.0 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AEO60747.1 - 2.3e-16 59.4 0.0 6.5e-16 58.0 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 AEO60747.1 - 2.4e-10 40.9 0.0 1.7e-09 38.1 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 AEO60747.1 - 9.3e-09 34.6 0.0 2.7e-08 33.1 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus POM121 PF15229.1 AEO60747.1 - 0.0012 18.3 0.4 0.0021 17.5 0.3 1.3 1 0 0 1 1 1 1 POM121 family Hydrolase_3 PF08282.7 AEO60747.1 - 0.0014 18.2 0.3 0.0014 18.2 0.2 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Git3 PF11710.3 AEO60748.1 - 0.00087 18.9 12.1 0.18 11.3 4.6 2.3 1 1 1 2 2 2 2 G protein-coupled glucose receptor regulating Gpa2 Dicty_CAR PF05462.6 AEO60748.1 - 0.091 11.6 18.3 0.25 10.2 3.1 3.0 2 1 1 3 3 3 0 Slime mold cyclic AMP receptor Mannitol_dh_C PF08125.8 AEO60749.1 - 2.8e-45 154.4 0.1 3.7e-45 154.0 0.1 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 AEO60749.1 - 2.3e-20 73.0 0.4 1e-19 70.9 0.0 2.1 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain UDPG_MGDP_dh_N PF03721.9 AEO60749.1 - 0.0046 16.3 0.1 0.014 14.7 0.0 1.9 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UPF0181 PF03701.9 AEO60749.1 - 0.042 13.1 0.4 0.093 12.0 0.3 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0181) Coatomer_WDAD PF04053.9 AEO60750.1 - 3.1e-173 576.6 0.0 1.5e-171 571.0 0.0 2.1 2 0 0 2 2 2 2 Coatomer WD associated region WD40 PF00400.27 AEO60750.1 - 6.6e-47 155.7 7.4 6.4e-10 38.5 0.0 8.3 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 AEO60750.1 - 2.9e-06 25.7 4.2 0.0047 15.1 0.1 4.7 1 1 2 4 4 4 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 AEO60750.1 - 0.00018 21.2 0.1 0.23 11.2 0.0 3.4 2 2 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region CRAL_TRIO PF00650.15 AEO60751.1 - 2.1e-25 89.0 0.0 2.9e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 AEO60751.1 - 1.6e-10 40.9 0.0 4.1e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Acid_PPase PF12689.2 AEO60752.1 - 2.3e-49 167.2 0.0 2.8e-49 166.9 0.0 1.1 1 0 0 1 1 1 1 Acid Phosphatase HAD_2 PF13419.1 AEO60752.1 - 0.00044 20.5 0.1 0.19 11.9 0.0 2.9 3 0 0 3 3 3 2 Haloacid dehalogenase-like hydrolase FlgN PF05130.7 AEO60753.1 - 0.0051 17.0 1.4 0.0081 16.4 1.0 1.4 1 0 0 1 1 1 1 FlgN protein APG6 PF04111.7 AEO60753.1 - 0.0056 15.7 0.5 0.0069 15.4 0.3 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 OmpH PF03938.9 AEO60753.1 - 0.036 13.9 0.4 0.047 13.6 0.3 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1599 PF07659.6 AEO60753.1 - 0.086 12.9 2.6 5.7 7.0 0.1 2.3 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1599) DUF1664 PF07889.7 AEO60753.1 - 0.15 11.8 0.3 0.23 11.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Fzo_mitofusin PF04799.8 AEO60753.1 - 0.2 11.0 1.1 0.29 10.5 0.8 1.2 1 0 0 1 1 1 0 fzo-like conserved region DUF724 PF05266.9 AEO60753.1 - 0.22 11.1 3.0 0.61 9.6 2.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF724) CALCOCO1 PF07888.6 AEO60753.1 - 1.5 7.0 9.3 1.9 6.7 6.5 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2852 PF11014.3 AEO60753.1 - 2.5 8.0 6.2 2.6 8.0 3.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) Glyoxalase PF00903.20 AEO60754.1 - 1.2e-08 34.9 6.6 2.8e-07 30.5 1.7 2.7 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 AEO60754.1 - 3.7e-05 24.2 3.5 0.097 13.2 0.2 2.3 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 AEO60754.1 - 0.044 13.7 0.5 0.18 11.8 0.1 2.2 2 1 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Pkinase_Tyr PF07714.12 AEO60755.1 - 8.4e-08 31.5 0.0 1.2e-05 24.5 0.0 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 AEO60755.1 - 9.2e-07 28.2 0.0 7.3e-06 25.3 0.0 1.9 1 1 1 2 2 2 1 Protein kinase domain APH PF01636.18 AEO60755.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family PBP PF01161.15 AEO60756.1 - 9.8e-24 83.8 0.0 1.2e-23 83.5 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF3439 PF11921.3 AEO60756.1 - 0.044 13.5 6.8 0.72 9.6 4.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Het-C PF07217.6 AEO60758.1 - 0.09 10.9 0.0 0.13 10.3 0.0 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C DUF3129 PF11327.3 AEO60759.1 - 4.8e-74 248.1 2.4 7.1e-74 247.6 1.7 1.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3129) AA_permease PF00324.16 AEO60760.1 - 1.8e-122 409.0 38.8 2.1e-122 408.8 26.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AEO60760.1 - 3.8e-30 104.7 42.9 4.7e-30 104.4 29.8 1.1 1 0 0 1 1 1 1 Amino acid permease PAF-AH_p_II PF03403.8 AEO60761.1 - 5.2e-13 48.0 0.1 1.3e-12 46.7 0.1 1.5 2 0 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 AEO60761.1 - 5e-05 23.0 0.1 7.8e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.6 AEO60761.1 - 0.00018 20.4 0.0 0.00021 20.1 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.2 AEO60761.1 - 0.004 16.0 0.0 0.0058 15.5 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.3 AEO60761.1 - 0.0047 16.7 1.6 0.0054 16.5 0.0 1.9 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_6 PF12697.2 AEO60761.1 - 0.045 13.6 0.1 0.078 12.8 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Pectinesterase PF01095.14 AEO60762.1 - 2.4e-50 170.7 4.6 3.1e-50 170.4 3.2 1.0 1 0 0 1 1 1 1 Pectinesterase Glyco_hydro_16 PF00722.16 AEO60763.1 - 3.7e-14 52.4 0.3 1.2e-13 50.7 0.2 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 AEO60763.1 - 4.7e-07 28.3 5.0 8.8e-05 20.8 0.1 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) DUF456 PF04306.8 AEO60764.1 - 0.038 14.0 1.1 0.038 14.0 0.8 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF456) Tyrosinase PF00264.15 AEO60765.1 - 4.9e-47 160.9 0.0 6.5e-47 160.5 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Abhydrolase_6 PF12697.2 AEO60766.1 - 1.1e-20 74.5 0.7 5.5e-20 72.2 0.5 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO60766.1 - 4.6e-09 36.1 0.0 0.0021 17.8 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO60766.1 - 7.5e-07 28.9 0.0 2.2e-06 27.4 0.0 2.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold ATP-synt_E PF05680.7 AEO60767.1 - 0.07 13.0 5.4 0.13 12.2 3.7 1.4 1 0 0 1 1 1 0 ATP synthase E chain DUF3808 PF10300.4 AEO60768.1 - 5.2e-128 427.5 0.0 6.6e-128 427.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) DSS1_SEM1 PF05160.8 AEO60769.1 - 3.6e-25 87.5 14.4 3.6e-25 87.5 10.0 1.4 1 1 0 1 1 1 1 DSS1/SEM1 family GHL15 PF14885.1 AEO60769.1 - 0.075 13.2 0.0 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 15 PGK PF00162.14 AEO60770.1 - 3.1e-152 506.6 1.0 3.5e-152 506.4 0.7 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase FIVAR PF07554.8 AEO60770.1 - 0.039 14.1 5.0 2.1 8.6 0.0 4.1 4 0 0 4 4 4 0 Uncharacterised Sugar-binding Domain Mpv17_PMP22 PF04117.7 AEO60771.1 - 7.5e-24 83.1 0.5 2.6e-23 81.4 0.1 2.0 2 0 0 2 2 2 1 Mpv17 / PMP22 family Kinocilin PF15033.1 AEO60772.1 - 0.0026 17.2 0.2 0.005 16.3 0.1 1.4 1 0 0 1 1 1 1 Kinocilin protein TMEM154 PF15102.1 AEO60772.1 - 0.014 15.0 0.0 0.025 14.2 0.0 1.5 1 1 0 1 1 1 0 TMEM154 protein family Adeno_E3_CR2 PF02439.10 AEO60772.1 - 0.094 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SKG6 PF08693.5 AEO60772.1 - 0.1 11.9 0.1 0.1 11.9 0.0 2.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Plasmodium_Vir PF05795.6 AEO60772.1 - 0.12 11.5 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein APH PF01636.18 AEO60773.1 - 5.3e-06 26.3 0.2 5.3e-06 26.3 0.1 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF4135 PF13575.1 AEO60773.1 - 0.047 12.6 0.1 0.078 11.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) MFS_1 PF07690.11 AEO60774.1 - 2.2e-13 49.6 23.4 5.3e-12 45.1 11.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.11 AEO60774.1 - 0.0025 17.3 1.3 0.0073 15.8 0.9 1.8 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 DHO_dh PF01180.16 AEO60775.1 - 3.5e-65 219.8 0.0 1.1e-64 218.2 0.0 1.7 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase Mpv17_PMP22 PF04117.7 AEO60775.1 - 1.8e-16 59.4 1.1 4e-16 58.4 0.2 2.1 1 1 1 2 2 2 1 Mpv17 / PMP22 family PcrB PF01884.12 AEO60775.1 - 0.00073 18.8 0.7 0.56 9.4 0.1 2.2 2 0 0 2 2 2 2 PcrB family FMN_dh PF01070.13 AEO60775.1 - 0.13 11.0 1.0 0.32 9.8 0.1 2.0 2 0 0 2 2 2 0 FMN-dependent dehydrogenase FAD_binding_3 PF01494.14 AEO60776.1 - 3.1e-06 26.4 0.0 4.8e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Carn_acyltransf PF00755.15 AEO60777.1 - 4.6e-39 133.9 0.0 5.4e-39 133.7 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase OrfB_Zn_ribbon PF07282.6 AEO60778.1 - 7.1e-05 22.3 9.1 0.14 11.8 0.1 4.0 2 1 2 4 4 4 2 Putative transposase DNA-binding domain DZR PF12773.2 AEO60778.1 - 0.0028 17.4 11.1 0.76 9.6 3.2 3.0 1 1 2 3 3 3 3 Double zinc ribbon DNA_RNApol_7kD PF03604.8 AEO60778.1 - 0.11 11.9 0.1 0.11 11.9 0.0 2.7 3 1 1 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit DUF1561 PF07598.6 AEO60778.1 - 0.15 10.0 0.5 0.18 9.6 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1561) PADR1 PF08063.7 AEO60778.1 - 2.6 7.4 9.8 5.8 6.3 0.3 3.3 4 0 0 4 4 4 0 PADR1 (NUC008) domain p450 PF00067.17 AEO60779.1 - 5.3e-63 213.1 0.0 6.7e-63 212.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_L1 PF00687.16 AEO60780.1 - 1e-56 191.7 0.0 1e-56 191.7 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family Nbl1_Borealin_N PF10444.4 AEO60780.1 - 0.17 11.2 1.8 0.14 11.5 0.2 1.7 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal FAD_binding_4 PF01565.18 AEO60782.1 - 4.4e-32 110.4 0.9 7.5e-32 109.7 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 AEO60782.1 - 0.074 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Berberine and berberine like FAD_binding_4 PF01565.18 AEO60784.1 - 3.1e-30 104.4 0.3 7.7e-30 103.1 0.2 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 AEO60784.1 - 0.00029 20.6 0.1 0.00059 19.6 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like NolV PF06635.7 AEO60784.1 - 0.094 11.8 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein NolV SSP160 PF06933.6 AEO60784.1 - 0.65 7.8 14.3 0.97 7.3 9.9 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Dicty_REP PF05086.7 AEO60784.1 - 1.1 6.9 4.9 1.4 6.5 3.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein UbiA PF01040.13 AEO60785.1 - 5.1e-31 107.8 23.0 7.3e-31 107.3 16.0 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family adh_short PF00106.20 AEO60786.1 - 1.6e-08 34.6 3.7 2.6e-08 33.9 0.4 2.2 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 AEO60786.1 - 1.9e-06 27.6 0.2 3.6e-06 26.7 0.1 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 AEO60786.1 - 0.081 11.8 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein MFS_1 PF07690.11 AEO60787.1 - 2e-31 109.0 28.6 2e-31 109.0 19.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily WTF PF03303.8 AEO60789.1 - 0.95 8.8 5.6 4.1 6.7 0.5 2.2 2 0 0 2 2 2 0 WTF protein Fijivirus_P9-2 PF06837.6 AEO60789.1 - 2.9 6.9 6.9 4.7 6.2 4.8 1.3 1 0 0 1 1 1 0 Fijivirus P9-2 protein Cupin_2 PF07883.6 AEO60790.1 - 3.7e-05 23.1 0.0 7.7e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Palm_thioest PF02089.10 AEO60791.1 - 7.9e-58 195.6 0.0 9.7e-58 195.3 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.6 AEO60791.1 - 0.013 14.6 0.0 0.09 11.8 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase_2 PF01674.13 AEO60791.1 - 0.045 13.0 0.0 0.18 11.1 0.0 2.0 1 1 0 1 1 1 0 Lipase (class 2) Abhydrolase_1 PF00561.15 AEO60791.1 - 0.12 11.9 0.0 0.17 11.3 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold adh_short PF00106.20 AEO60792.1 - 8e-20 71.4 0.1 1.2e-19 70.7 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO60792.1 - 1.7e-12 47.6 0.2 2e-12 47.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO60792.1 - 3e-05 23.7 0.2 0.00019 21.1 0.0 1.9 1 1 1 2 2 2 1 KR domain FlgN PF05130.7 AEO60793.1 - 0.0051 17.0 1.4 0.0081 16.4 1.0 1.4 1 0 0 1 1 1 1 FlgN protein APG6 PF04111.7 AEO60793.1 - 0.0056 15.7 0.5 0.0069 15.4 0.3 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 OmpH PF03938.9 AEO60793.1 - 0.036 13.9 0.4 0.047 13.6 0.3 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1599 PF07659.6 AEO60793.1 - 0.086 12.9 2.6 5.7 7.0 0.1 2.3 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1599) DUF1664 PF07889.7 AEO60793.1 - 0.15 11.8 0.3 0.23 11.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Fzo_mitofusin PF04799.8 AEO60793.1 - 0.2 11.0 1.1 0.29 10.5 0.8 1.2 1 0 0 1 1 1 0 fzo-like conserved region DUF724 PF05266.9 AEO60793.1 - 0.22 11.1 3.0 0.61 9.6 2.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF724) CALCOCO1 PF07888.6 AEO60793.1 - 1.5 7.0 9.3 1.9 6.7 6.5 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2852 PF11014.3 AEO60793.1 - 2.5 8.0 6.2 2.6 8.0 3.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) RVT_2 PF07727.9 AEO60794.1 - 0.0035 16.3 0.0 0.0053 15.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PocR PF10114.4 AEO60796.1 - 0.81 8.8 2.7 1.1 8.3 1.9 1.2 1 0 0 1 1 1 0 Sensory domain found in PocR MFS_1 PF07690.11 AEO60798.1 - 1e-22 80.3 57.5 2e-21 76.0 14.7 3.0 1 1 1 3 3 3 2 Major Facilitator Superfamily WaaY PF06176.6 AEO60799.1 - 0.00037 19.7 0.0 0.00049 19.4 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase PF00069.20 AEO60799.1 - 0.092 11.8 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain Epiglycanin_C PF14654.1 AEO60800.1 - 0.021 14.8 1.0 0.056 13.4 0.1 2.2 3 0 0 3 3 3 0 Mucin, catalytic, TM and cytoplasmic tail region DUF2165 PF09933.4 AEO60800.1 - 0.081 12.6 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Predicted small integral membrane protein (DUF2165) zf-RING_2 PF13639.1 AEO60803.1 - 1.2e-09 37.8 7.1 2.2e-09 36.9 4.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 AEO60803.1 - 1.1e-08 35.0 4.0 2.6e-08 33.8 2.8 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger FANCL_C PF11793.3 AEO60803.1 - 9.7e-07 28.6 5.1 2.4e-06 27.4 3.6 1.7 1 0 0 1 1 1 1 FANCL C-terminal domain zf-Apc11 PF12861.2 AEO60803.1 - 9.7e-06 25.3 3.1 2.6e-05 23.9 2.1 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 AEO60803.1 - 7.5e-05 22.3 8.9 0.00014 21.4 6.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 AEO60803.1 - 0.00023 20.7 3.8 0.00038 20.0 2.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AEO60803.1 - 0.00046 20.1 8.8 0.00087 19.2 6.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 AEO60803.1 - 0.00076 19.4 7.1 0.0015 18.5 4.9 1.5 1 0 0 1 1 1 1 RING-variant domain C1_1 PF00130.17 AEO60803.1 - 0.027 14.2 2.1 0.054 13.2 1.5 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_5 PF14634.1 AEO60803.1 - 0.039 13.6 8.7 0.067 12.9 6.0 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Baculo_RING PF05883.6 AEO60803.1 - 0.063 13.1 1.8 0.13 12.1 1.2 1.4 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-RING-like PF08746.6 AEO60803.1 - 0.11 12.4 7.7 0.23 11.5 5.3 1.5 1 0 0 1 1 1 0 RING-like domain zf-Nse PF11789.3 AEO60803.1 - 0.27 10.8 4.6 0.55 9.8 3.2 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 AEO60803.1 - 1.6 8.5 3.8 3.8 7.3 2.7 1.7 1 0 0 1 1 1 0 RING-type zinc-finger DAO PF01266.19 AEO60804.1 - 1.2e-27 96.7 5.5 1.6e-27 96.3 3.8 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 AEO60804.1 - 6.6e-05 22.8 0.3 0.00024 21.0 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 AEO60804.1 - 0.00051 18.9 0.0 0.00085 18.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 AEO60804.1 - 0.0054 16.6 0.0 0.0075 16.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 AEO60804.1 - 0.0072 15.4 1.4 0.016 14.3 0.1 2.0 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 AEO60804.1 - 0.0098 16.2 0.5 0.025 14.9 0.3 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 AEO60804.1 - 0.031 13.7 0.2 0.06 12.7 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.9 AEO60804.1 - 0.036 12.5 0.2 0.051 12.0 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein ALG3 PF05208.8 AEO60805.1 - 1.7e-150 501.3 15.6 2e-150 501.1 10.8 1.0 1 0 0 1 1 1 1 ALG3 protein DUF4027 PF13219.1 AEO60805.1 - 0.58 9.6 4.0 14 5.1 1.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4027) eIF-1a PF01176.14 AEO60806.1 - 7e-18 63.8 0.0 8.8e-18 63.4 0.0 1.1 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Spiralin PF05215.8 AEO60806.1 - 0.029 13.5 0.0 0.033 13.3 0.0 1.1 1 0 0 1 1 1 0 Spiralin DUF4159 PF13709.1 AEO60806.1 - 0.038 13.0 0.0 0.056 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4159) HAD PF12710.2 AEO60807.1 - 7.8e-15 55.5 0.0 1e-14 55.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 AEO60807.1 - 2.7e-05 24.4 0.0 7.1e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 AEO60807.1 - 7.8e-05 21.9 0.0 0.0018 17.4 0.0 2.1 2 0 0 2 2 2 1 Putative Phosphatase UMPH-1 PF05822.7 AEO60807.1 - 0.00037 19.8 0.0 0.00057 19.2 0.0 1.4 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.21 AEO60807.1 - 0.038 14.3 0.1 1.1 9.5 0.0 2.6 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase She9_MDM33 PF05546.6 AEO60808.1 - 1.7e-80 269.4 2.0 3e-80 268.6 1.4 1.3 1 0 0 1 1 1 1 She9 / Mdm33 family Adaptin_binding PF10199.4 AEO60808.1 - 0.044 14.0 1.4 0.15 12.2 1.0 2.0 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 DUF566 PF04484.7 AEO60808.1 - 0.069 12.6 22.1 0.14 11.6 15.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF566) Macoilin PF09726.4 AEO60808.1 - 0.12 10.6 11.5 0.19 9.9 8.0 1.4 1 0 0 1 1 1 0 Transmembrane protein PAS_9 PF13426.1 AEO60808.1 - 0.13 12.6 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 PAS domain PsbH PF00737.15 AEO60808.1 - 0.15 11.6 0.4 0.26 10.9 0.3 1.3 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein ADIP PF11559.3 AEO60808.1 - 0.19 11.6 5.9 0.051 13.4 1.1 2.1 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding Herpes_capsid PF06112.6 AEO60808.1 - 2.1 8.3 32.1 2.8 7.9 0.0 2.5 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein DUF904 PF06005.7 AEO60808.1 - 2.4 8.4 5.7 3.6 7.9 1.4 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF904) Sec3_C PF09763.4 AEO60808.1 - 4.6 5.2 4.8 6.1 4.8 3.3 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 DUF605 PF04652.11 AEO60808.1 - 8.9 5.5 30.8 14 4.9 21.4 1.3 1 0 0 1 1 1 0 Vta1 like Acyl-CoA_dh_1 PF00441.19 AEO60809.1 - 7.7e-42 142.9 4.5 1.2e-41 142.3 3.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 AEO60809.1 - 1.4e-28 99.7 0.7 3.9e-28 98.2 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 AEO60809.1 - 1.3e-17 63.0 0.3 4.1e-17 61.4 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 AEO60809.1 - 3.5e-17 62.9 1.1 6.4e-17 62.0 0.8 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 AEO60809.1 - 0.033 13.5 0.1 0.14 11.5 0.1 1.9 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal DUF3184 PF11380.3 AEO60809.1 - 0.076 10.9 0.5 0.1 10.5 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3184) Ribosom_S12_S23 PF00164.20 AEO60810.1 - 2.2e-40 136.8 0.8 2.8e-40 136.5 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Glyco_transf_15 PF01793.11 AEO60811.1 - 1.1e-144 481.4 8.5 1.3e-144 481.2 5.9 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Hemopexin PF00045.14 AEO60811.1 - 0.22 11.2 2.6 9.3 6.0 0.0 3.8 4 0 0 4 4 4 0 Hemopexin CDI PF02234.14 AEO60811.1 - 0.26 11.1 2.8 0.29 10.9 0.8 1.9 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor PAT1 PF09770.4 AEO60812.1 - 6.2e-240 798.7 19.7 7.1e-240 798.5 13.7 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Sin_N PF04801.8 AEO60813.1 - 1.9e-14 53.3 0.0 3e-13 49.4 0.0 2.1 1 1 0 1 1 1 1 Sin-like protein conserved region SOR_SNZ PF01680.12 AEO60815.1 - 1.6e-102 341.4 9.3 2.2e-102 341.0 6.4 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 AEO60815.1 - 1.8e-06 27.2 12.4 0.00066 18.8 0.6 3.1 1 1 3 4 4 4 2 Thiazole biosynthesis protein ThiG Dus PF01207.12 AEO60815.1 - 0.00011 21.0 0.3 0.11 11.3 0.0 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 AEO60815.1 - 0.00058 19.1 0.6 0.024 13.9 0.1 2.4 2 0 0 2 2 2 1 Histidine biosynthesis protein NanE PF04131.9 AEO60815.1 - 0.016 14.2 2.6 0.1 11.5 0.0 2.9 2 2 1 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase Trp_syntA PF00290.15 AEO60815.1 - 0.024 13.1 0.0 0.042 12.3 0.0 1.4 1 0 0 1 1 1 0 Tryptophan synthase alpha chain SNO PF01174.14 AEO60816.1 - 2.7e-56 190.1 0.1 2.9e-45 154.2 0.0 2.0 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 AEO60816.1 - 1.6e-11 44.0 0.1 2.7e-09 36.7 0.0 2.2 2 0 0 2 2 2 2 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 AEO60816.1 - 0.00065 19.1 0.6 0.0098 15.3 0.4 2.1 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_S51 PF03575.12 AEO60816.1 - 0.00072 19.3 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S51 DJ-1_PfpI PF01965.19 AEO60816.1 - 0.0046 16.4 0.0 0.0073 15.7 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 AEO60816.1 - 0.024 13.8 0.1 0.038 13.2 0.1 1.3 1 0 0 1 1 1 0 Putative amidotransferase OTT_1508_deam PF14441.1 AEO60817.1 - 2e-23 82.7 0.1 6.3e-23 81.1 0.0 1.7 2 0 0 2 2 2 1 OTT_1508-like deaminase zf-H2C2_2 PF13465.1 AEO60819.1 - 0.0052 17.0 8.4 0.18 12.1 0.1 3.5 3 1 0 3 3 3 1 Zinc-finger double domain zf-Di19 PF05605.7 AEO60819.1 - 0.0052 16.8 5.2 0.059 13.5 3.6 2.0 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.1 AEO60819.1 - 0.0089 15.6 0.9 0.0089 15.6 0.6 3.1 3 0 0 3 3 3 1 zinc-finger of a C2HC-type DZR PF12773.2 AEO60819.1 - 0.011 15.5 1.7 0.038 13.8 1.2 1.8 1 1 0 1 1 1 0 Double zinc ribbon zf-C2H2_4 PF13894.1 AEO60819.1 - 0.029 14.6 12.8 0.06 13.6 3.4 2.7 2 1 0 2 2 2 0 C2H2-type zinc finger zf-CHY PF05495.7 AEO60819.1 - 0.034 14.2 4.9 0.09 12.9 3.4 1.7 1 1 0 1 1 1 0 CHY zinc finger ROS_MUCR PF05443.6 AEO60819.1 - 0.037 13.8 2.2 1 9.1 0.0 2.0 1 1 1 2 2 2 0 ROS/MUCR transcriptional regulator protein zf-C3HC4_3 PF13920.1 AEO60819.1 - 0.074 12.7 4.2 1.6 8.4 0.1 2.4 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_Tnp_IS1595 PF12760.2 AEO60819.1 - 0.12 12.1 5.0 3.9 7.3 0.8 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-CHCC PF10276.4 AEO60819.1 - 0.2 11.5 2.0 1.9 8.3 0.4 2.5 2 0 0 2 2 2 0 Zinc-finger domain DUF3795 PF12675.2 AEO60819.1 - 0.31 11.2 2.4 0.6 10.3 1.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3795) zf-ISL3 PF14690.1 AEO60819.1 - 0.33 11.0 5.0 5.3 7.1 0.5 2.4 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DUF3505 PF12013.3 AEO60819.1 - 0.33 11.2 4.9 1.1 9.4 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3505) zf-ribbon_3 PF13248.1 AEO60819.1 - 0.36 10.1 1.9 9.3 5.6 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc-ribbons_6 PF07191.7 AEO60819.1 - 0.37 10.6 2.3 12 5.8 0.2 2.2 1 1 0 1 1 1 0 zinc-ribbons HypA PF01155.14 AEO60819.1 - 0.55 9.9 3.3 2.1 8.0 2.3 1.9 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family PSCyt3 PF07627.6 AEO60819.1 - 0.56 10.1 2.6 1.9 8.3 0.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1588) Cytochrom_CIII PF02085.11 AEO60819.1 - 0.7 10.0 6.6 0.87 9.7 4.6 1.2 1 0 0 1 1 1 0 Class III cytochrome C family Ogr_Delta PF04606.7 AEO60819.1 - 0.71 9.5 4.8 1.3 8.7 0.7 2.2 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger Sgf11 PF08209.6 AEO60819.1 - 0.81 9.0 9.1 0.88 8.9 2.8 2.7 2 1 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Cytochrom_c3_2 PF14537.1 AEO60819.1 - 1.5 9.2 5.8 2.8 8.3 4.0 1.6 1 1 0 1 1 1 0 Cytochrome c3 FYVE PF01363.16 AEO60819.1 - 1.9 8.4 6.5 2.3 8.1 0.7 2.1 2 0 0 2 2 2 0 FYVE zinc finger Zn_ribbon_recom PF13408.1 AEO60819.1 - 2.4 8.4 5.3 1.5 9.1 1.1 2.1 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-C2H2_2 PF12756.2 AEO60819.1 - 2.8 8.1 6.1 0.58 10.3 0.7 1.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 AEO60819.1 - 2.8 8.4 18.4 0.42 11.0 1.0 3.2 2 1 0 2 2 2 0 Zinc finger, C2H2 type FAR1 PF03101.10 AEO60820.1 - 1.8e-09 37.9 1.2 1.8e-09 37.9 0.8 2.3 2 0 0 2 2 2 1 FAR1 DNA-binding domain TusA PF01206.12 AEO60820.1 - 0.029 13.9 0.0 0.06 12.9 0.0 1.5 1 0 0 1 1 1 0 Sulfurtransferase TusA Vinculin PF01044.14 AEO60820.1 - 0.92 7.4 6.4 1.2 7.0 4.5 1.1 1 0 0 1 1 1 0 Vinculin family AFT PF08731.6 AEO60820.1 - 1.8 8.8 6.3 1.2 9.3 2.4 2.2 2 1 0 2 2 2 0 Transcription factor AFT SKG6 PF08693.5 AEO60821.1 - 0.018 14.3 0.3 0.041 13.2 0.2 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Thioredoxin PF00085.15 AEO60822.1 - 1.7e-26 91.8 0.0 2.1e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 AEO60822.1 - 1.5e-07 31.5 0.0 1.8e-06 28.1 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 AEO60822.1 - 6.4e-06 26.2 0.1 0.0017 18.4 0.0 2.7 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_9 PF14595.1 AEO60822.1 - 0.0015 18.0 0.0 0.0018 17.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 AEO60822.1 - 0.0072 15.8 0.1 0.083 12.4 0.0 2.0 1 1 1 2 2 2 1 Redoxin WSC PF01822.14 AEO60823.1 - 6.3e-20 70.8 4.4 6.3e-20 70.8 3.1 1.7 2 0 0 2 2 2 1 WSC domain SSP160 PF06933.6 AEO60823.1 - 9 4.1 8.8 12 3.6 6.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DcpS_C PF11969.3 AEO60824.1 - 6.6e-15 55.3 0.7 3.4e-09 36.9 0.1 2.2 2 0 0 2 2 2 2 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 AEO60824.1 - 2.2e-12 47.3 0.0 4.1e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 HIT domain Nuf2 PF03800.9 AEO60826.1 - 2.1e-45 154.3 0.3 1.3e-44 151.7 0.0 2.3 2 0 0 2 2 2 1 Nuf2 family Reo_sigmaC PF04582.7 AEO60826.1 - 2.9 6.9 14.2 2.2 7.3 2.0 2.9 1 1 1 3 3 3 0 Reovirus sigma C capsid protein MscS_porin PF12795.2 AEO60826.1 - 5.2 6.3 50.3 0.49 9.6 18.6 3.0 1 1 2 3 3 3 0 Mechanosensitive ion channel porin domain Adaptin_N PF01602.15 AEO60828.1 - 1e-97 327.6 0.0 1.2e-97 327.4 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 AEO60828.1 - 1.9e-13 50.5 4.9 6.6e-06 26.3 0.0 4.8 3 1 0 3 3 3 3 HEAT repeats HEAT PF02985.17 AEO60828.1 - 4.2e-09 35.7 0.5 0.047 13.7 0.0 5.8 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 AEO60828.1 - 1.9e-06 28.1 8.7 0.0015 18.9 0.0 5.7 5 0 0 5 5 5 1 HEAT-like repeat Cohesin_HEAT PF12765.2 AEO60828.1 - 0.0049 16.7 0.2 0.63 10.0 0.0 3.0 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.2 AEO60828.1 - 0.009 15.8 0.2 0.14 12.0 0.0 2.5 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Nop14 PF04147.7 AEO60828.1 - 1.1 7.0 31.1 1.7 6.4 21.5 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 AEO60828.1 - 1.2 8.2 32.9 1.9 7.6 22.8 1.1 1 0 0 1 1 1 0 SDA1 Daxx PF03344.10 AEO60828.1 - 1.6 7.1 26.6 2.3 6.6 18.4 1.1 1 0 0 1 1 1 0 Daxx Family Cwf_Cwc_15 PF04889.7 AEO60828.1 - 5.2 6.7 21.3 7.8 6.1 14.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CENP-T PF15511.1 AEO60828.1 - 8.7 5.4 21.9 3.6 6.7 12.9 2.0 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T PP-binding PF00550.20 AEO60830.1 - 4.3e-06 26.8 0.0 4.9e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site Metallophos PF00149.23 AEO60835.1 - 5.7e-42 143.3 0.9 7e-42 143.0 0.7 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Rho_GDI PF02115.12 AEO60836.1 - 1.3e-54 184.6 0.1 1.4e-54 184.5 0.1 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor E1_DerP2_DerF2 PF02221.10 AEO60836.1 - 0.022 15.0 0.0 0.048 13.9 0.0 1.7 1 1 0 1 1 1 0 ML domain KilA-N PF04383.8 AEO60837.1 - 0.018 14.6 0.0 0.051 13.1 0.0 1.7 1 1 1 2 2 2 0 KilA-N domain NAD_binding_2 PF03446.10 AEO60838.1 - 5.2e-37 127.1 0.0 7.8e-37 126.6 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 AEO60838.1 - 2.3e-32 111.5 0.0 4.9e-32 110.5 0.0 1.6 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase OCD_Mu_crystall PF02423.10 AEO60838.1 - 4.7e-08 32.1 0.0 7.5e-08 31.5 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.12 AEO60838.1 - 1.8e-06 28.2 0.1 5.8e-06 26.6 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.17 AEO60838.1 - 5.5e-05 23.6 0.0 0.00017 22.0 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold TrkA_N PF02254.13 AEO60838.1 - 0.00066 19.6 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Semialdhyde_dh PF01118.19 AEO60838.1 - 0.012 15.9 0.0 0.028 14.7 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DUF3053 PF11254.3 AEO60838.1 - 0.13 11.5 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) RTA1 PF04479.8 AEO60839.1 - 8.7e-36 123.5 1.3 1.2e-35 123.0 0.9 1.1 1 0 0 1 1 1 1 RTA1 like protein Nucleo_P87 PF07267.6 AEO60840.1 - 2.8 6.5 6.4 3.8 6.0 4.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 RhoGEF PF00621.15 AEO60841.1 - 8.7e-27 94.1 0.6 3.7e-26 92.0 0.0 2.1 2 0 0 2 2 2 1 RhoGEF domain DUF3507 PF12015.3 AEO60841.1 - 0.003 17.0 0.0 0.0064 16.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) Bacillus_HBL PF05791.6 AEO60841.1 - 0.054 12.8 1.3 0.48 9.7 0.4 2.4 1 1 2 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) DUF3584 PF12128.3 AEO60841.1 - 0.94 6.7 12.9 1.8 5.7 9.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1451 PF07295.6 AEO60841.1 - 2.1 8.0 5.2 1.2 8.9 1.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1451) AAA_13 PF13166.1 AEO60841.1 - 8.2 4.7 10.7 18 3.6 7.4 1.4 1 0 0 1 1 1 0 AAA domain HORMA PF02301.13 AEO60842.1 - 6.4e-17 61.7 0.0 2.1e-13 50.2 0.0 2.9 2 1 0 2 2 2 2 HORMA domain DUF605 PF04652.11 AEO60842.1 - 4.4 6.6 8.6 6 6.1 5.9 1.2 1 0 0 1 1 1 0 Vta1 like IBN_N PF03810.14 AEO60843.1 - 3.4e-13 49.3 0.0 2.7e-10 40.0 0.0 3.9 4 0 0 4 4 4 1 Importin-beta N-terminal domain CAS_CSE1 PF03378.10 AEO60843.1 - 0.00024 19.5 0.0 0.0027 16.0 0.0 2.1 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Xpo1 PF08389.7 AEO60843.1 - 0.0015 18.4 0.0 0.025 14.4 0.0 3.1 2 1 0 2 2 2 1 Exportin 1-like protein PI31_Prot_N PF11566.3 AEO60844.1 - 9.8e-35 119.4 0.0 1.2e-34 119.0 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 AEO60844.1 - 3.5e-17 62.8 21.7 3.5e-17 62.8 15.1 3.2 3 2 0 3 3 3 1 PI31 proteasome regulator DUF2036 PF09724.4 AEO60846.1 - 1.1e-08 34.5 0.0 1.3e-08 34.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) IBR PF01485.16 AEO60847.1 - 7.1e-05 22.5 30.5 0.0017 18.1 5.7 3.5 3 0 0 3 3 3 2 IBR domain Rad4 PF03835.10 AEO60848.1 - 1.3e-32 112.1 0.1 5.2e-32 110.2 0.0 2.1 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 AEO60848.1 - 2.3e-26 91.2 0.1 5.2e-26 90.1 0.1 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 AEO60848.1 - 1.4e-19 69.3 0.3 3.1e-19 68.2 0.2 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 AEO60848.1 - 8.3e-18 64.4 0.4 8.3e-18 64.4 0.3 3.9 5 0 0 5 5 5 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 AEO60848.1 - 0.00067 19.8 0.0 0.0027 17.8 0.0 2.2 1 1 0 1 1 1 1 Transglutaminase-like superfamily zf-AN1 PF01428.11 AEO60849.1 - 7e-25 86.6 16.0 1.1e-13 50.7 5.0 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.16 AEO60849.1 - 0.0025 17.6 10.9 0.27 11.1 2.3 2.5 2 0 0 2 2 2 2 IBR domain Transp_Tc5_C PF04236.10 AEO60849.1 - 0.53 10.5 12.7 0.2 11.8 3.5 2.3 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain HypA PF01155.14 AEO60849.1 - 6.9 6.3 6.5 0.69 9.6 0.4 2.1 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family MTP18 PF10558.4 AEO60850.1 - 1.9e-68 229.0 0.0 2.5e-68 228.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) Lebercilin PF15619.1 AEO60850.1 - 0.094 12.1 0.4 0.15 11.4 0.3 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF2611 PF11022.3 AEO60851.1 - 7.9e-28 96.3 0.3 8.8e-28 96.2 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) UPF0126 PF03458.8 AEO60851.1 - 0.16 11.5 2.4 0.21 11.2 1.7 1.1 1 0 0 1 1 1 0 UPF0126 domain RuBisCO_large_N PF02788.11 AEO60853.1 - 0.056 13.1 0.3 0.086 12.5 0.2 1.3 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, N-terminal domain FlgN PF05130.7 AEO60855.1 - 0.0051 17.0 1.4 0.0081 16.4 1.0 1.4 1 0 0 1 1 1 1 FlgN protein APG6 PF04111.7 AEO60855.1 - 0.0056 15.7 0.5 0.0069 15.4 0.3 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 OmpH PF03938.9 AEO60855.1 - 0.036 13.9 0.4 0.047 13.6 0.3 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1599 PF07659.6 AEO60855.1 - 0.086 12.9 2.6 5.7 7.0 0.1 2.3 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1599) DUF1664 PF07889.7 AEO60855.1 - 0.15 11.8 0.3 0.23 11.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Fzo_mitofusin PF04799.8 AEO60855.1 - 0.2 11.0 1.1 0.29 10.5 0.8 1.2 1 0 0 1 1 1 0 fzo-like conserved region DUF724 PF05266.9 AEO60855.1 - 0.22 11.1 3.0 0.61 9.6 2.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF724) CALCOCO1 PF07888.6 AEO60855.1 - 1.5 7.0 9.3 1.9 6.7 6.5 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2852 PF11014.3 AEO60855.1 - 2.5 8.0 6.2 2.6 8.0 3.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) zf-CCHC PF00098.18 AEO60856.1 - 5.1e-05 22.9 1.5 7.8e-05 22.4 1.0 1.3 1 0 0 1 1 1 1 Zinc knuckle CHAD PF05235.9 AEO60857.1 - 0.00033 20.3 4.0 0.0005 19.7 2.8 1.2 1 0 0 1 1 1 1 CHAD domain MSP1_C PF07462.6 AEO60857.1 - 0.053 11.9 0.2 0.053 11.9 0.1 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Syntaxin-18_N PF10496.4 AEO60857.1 - 0.063 13.1 0.4 0.11 12.3 0.3 1.3 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus DEK_C PF08766.6 AEO60857.1 - 0.073 12.8 0.2 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 DEK C terminal domain DUF1059 PF06348.6 AEO60857.1 - 0.095 12.5 0.4 0.23 11.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1059) CHDCT2 PF08074.6 AEO60857.1 - 0.97 9.1 5.0 1.7 8.3 3.5 1.4 1 1 0 1 1 1 0 CHDCT2 (NUC038) domain EAP30 PF04157.11 AEO60859.1 - 1.9e-56 190.7 0.0 2.6e-56 190.3 0.0 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 AEO60859.1 - 5.1e-26 90.3 0.0 8.7e-26 89.5 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-Sec23_Sec24 PF04810.10 AEO60859.1 - 0.00032 20.1 3.7 0.0067 15.9 0.2 2.4 2 0 0 2 2 2 2 Sec23/Sec24 zinc finger GRAM PF02893.15 AEO60859.1 - 0.00035 20.0 0.0 0.00063 19.2 0.0 1.4 1 0 0 1 1 1 1 GRAM domain zf-RanBP PF00641.13 AEO60859.1 - 0.12 11.5 14.1 0.037 13.1 0.6 2.6 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others DZR PF12773.2 AEO60859.1 - 1.9 8.3 6.1 0.21 11.4 0.3 2.2 2 1 0 2 2 2 0 Double zinc ribbon SAC3_GANP PF03399.11 AEO60860.1 - 1.9e-70 236.5 0.6 2.5e-70 236.1 0.4 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 AEO60860.1 - 0.0017 18.1 0.1 0.0047 16.6 0.0 1.8 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 SH3_1 PF00018.23 AEO60861.1 - 1.1e-26 91.9 0.0 8.4e-14 50.6 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 AEO60861.1 - 4.9e-18 64.4 0.3 2.8e-09 36.3 0.0 2.9 3 0 0 3 3 3 2 Variant SH3 domain PX PF00787.19 AEO60861.1 - 2.1e-15 56.5 0.0 4.1e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.12 AEO60861.1 - 1.3e-12 46.9 0.0 1.2e-08 34.3 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.19 AEO60861.1 - 1.5e-08 34.1 0.0 2.5e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 PB1 domain HTH_Tnp_Tc5 PF03221.11 AEO60862.1 - 4.4e-15 55.2 1.2 7.9e-14 51.2 0.1 3.1 2 1 1 3 3 3 1 Tc5 transposase DNA-binding domain DUF4604 PF15377.1 AEO60862.1 - 0.064 13.4 0.3 0.12 12.5 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) HTH_29 PF13551.1 AEO60862.1 - 0.34 11.0 4.5 0.31 11.2 0.2 2.6 3 0 0 3 3 3 0 Winged helix-turn helix Dicty_REP PF05086.7 AEO60862.1 - 5.1 4.7 4.2 6.7 4.3 2.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3716 PF12511.3 AEO60864.1 - 3.7e-16 58.4 5.2 7e-16 57.5 3.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) CENP-C_C PF11699.3 AEO60864.1 - 0.02 14.8 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 Mif2/CENP-C like Cupin_3 PF05899.7 AEO60864.1 - 0.042 13.2 0.0 0.16 11.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF861) CoA_binding_2 PF13380.1 AEO60867.1 - 5.8e-25 87.7 0.0 7.4e-25 87.3 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain EF-hand_7 PF13499.1 AEO60868.1 - 1.7e-14 53.6 0.0 2.1e-10 40.5 0.0 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_9 PF14658.1 AEO60868.1 - 4.1e-12 45.8 0.0 4.7e-06 26.4 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_6 PF13405.1 AEO60868.1 - 3.3e-11 42.0 0.4 0.0088 15.8 0.0 4.1 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 AEO60868.1 - 7.3e-10 37.4 0.4 0.011 15.0 0.0 4.2 4 1 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 AEO60868.1 - 7.7e-10 38.2 0.1 0.00033 20.1 0.0 3.4 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 AEO60868.1 - 0.072 12.4 1.8 2 7.8 0.7 3.2 3 0 0 3 3 3 0 EF hand Peptidase_M3 PF01432.15 AEO60869.1 - 7.4e-160 532.9 0.0 9.5e-160 532.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.1 AEO60869.1 - 0.0034 17.4 0.0 0.0092 16.0 0.0 1.7 1 0 0 1 1 1 1 Effector protein Aa_trans PF01490.13 AEO60870.1 - 1.1e-60 205.2 36.0 1.3e-60 205.0 24.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PgaD PF13994.1 AEO60870.1 - 0.77 9.2 6.4 2.8 7.4 3.3 2.6 2 1 0 2 2 2 0 PgaD-like protein DUF3464 PF11947.3 AEO60870.1 - 0.94 8.9 6.2 0.082 12.3 0.5 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3464) DUF3285 PF11688.3 AEO60870.1 - 3.7 7.2 6.2 1.6 8.4 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3285) BIR PF00653.16 AEO60872.1 - 7.4e-42 141.6 2.6 2.8e-21 75.7 0.0 2.4 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain Pmp3 PF01679.12 AEO60873.1 - 1.7e-20 72.4 0.2 1.8e-20 72.3 0.2 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Mmp37 PF09139.6 AEO60874.1 - 2.8e-134 447.3 0.0 3.7e-134 446.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 MAD PF05557.8 AEO60875.1 - 1e-53 182.6 56.9 1.3e-53 182.2 39.5 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein muHD PF10291.4 AEO60876.1 - 1.8e-76 256.7 0.0 3.2e-76 255.9 0.0 1.4 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 AEO60876.1 - 0.0073 16.4 0.9 0.062 13.4 0.0 2.7 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain PAS_10 PF13596.1 AEO60876.1 - 0.08 13.2 2.1 0.22 11.8 0.1 2.5 3 0 0 3 3 3 0 PAS domain IZUMO PF15005.1 AEO60876.1 - 0.11 12.5 1.8 0.22 11.5 1.3 1.4 1 0 0 1 1 1 0 Izumo sperm-egg fusion Vps5 PF09325.5 AEO60876.1 - 0.2 10.8 9.5 0.14 11.3 4.9 1.8 2 0 0 2 2 2 0 Vps5 C terminal like DUF3584 PF12128.3 AEO60876.1 - 0.59 7.3 12.7 0.84 6.8 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Fib_alpha PF08702.5 AEO60876.1 - 1.1 9.3 4.1 2.6 8.1 2.9 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Pkinase PF00069.20 AEO60877.1 - 7.2e-33 113.8 0.0 8.8e-33 113.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO60877.1 - 8.1e-08 31.6 0.0 1.1e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase GATase PF00117.23 AEO60878.1 - 3.2e-41 140.8 0.0 5.7e-41 140.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 AEO60878.1 - 3.9e-38 129.0 0.1 8.4e-38 127.9 0.1 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.12 AEO60878.1 - 9.7e-12 44.2 0.1 3.4e-06 26.1 0.1 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 AEO60878.1 - 2.3e-09 37.0 0.0 4.5e-09 36.0 0.0 1.6 1 1 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.11 AEO60878.1 - 0.00022 19.9 0.1 0.00047 18.8 0.1 1.5 2 0 0 2 2 2 1 tRNA methyl transferase ThiI PF02568.9 AEO60878.1 - 0.00098 18.6 0.0 0.0028 17.1 0.0 1.7 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) QueC PF06508.8 AEO60878.1 - 0.0044 16.3 0.0 0.11 11.7 0.0 2.2 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Arginosuc_synth PF00764.14 AEO60878.1 - 0.0045 16.0 0.1 0.0068 15.4 0.1 1.2 1 0 0 1 1 1 1 Arginosuccinate synthase ATP_bind_3 PF01171.15 AEO60878.1 - 0.0061 16.0 0.0 0.014 14.8 0.0 1.6 2 0 0 2 2 2 1 PP-loop family Asn_synthase PF00733.16 AEO60878.1 - 0.0081 15.6 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase PAPS_reduct PF01507.14 AEO60878.1 - 0.056 13.2 0.0 0.097 12.4 0.0 1.4 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Spo12 PF05032.7 AEO60878.1 - 0.12 11.9 0.2 0.25 11.0 0.2 1.4 1 0 0 1 1 1 0 Spo12 family Fungal_trans_2 PF11951.3 AEO60880.1 - 7.6e-16 57.6 0.0 1.1e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO60880.1 - 1.1e-08 34.7 7.6 2e-08 33.9 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF605 PF04652.11 AEO60880.1 - 0.43 9.9 13.3 0.52 9.6 9.2 1.2 1 0 0 1 1 1 0 Vta1 like GST_N PF02798.15 AEO60881.1 - 1.8e-06 28.0 0.0 2e-06 27.9 0.0 1.0 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 AEO60881.1 - 3.1e-06 27.3 0.0 3.5e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 AEO60881.1 - 0.00023 21.0 0.1 0.00031 20.6 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 AEO60882.1 - 2.2e-07 30.6 0.1 2.9e-07 30.2 0.1 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 AEO60882.1 - 6.3e-06 26.0 0.0 8e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 AEO60882.1 - 6.8e-05 23.2 0.0 8.7e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SR-25 PF10500.4 AEO60883.1 - 3.9 6.8 8.0 0.93 8.9 3.3 1.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein WD40 PF00400.27 AEO60885.1 - 8.9e-05 22.2 6.7 0.38 10.7 0.3 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat PQ-loop PF04193.9 AEO60886.1 - 1.5e-23 82.0 13.2 5.1e-13 48.3 0.3 3.2 3 1 0 3 3 3 2 PQ loop repeat DUF1673 PF07895.6 AEO60886.1 - 0.024 14.1 0.4 0.024 14.1 0.3 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1673) DUF3796 PF12676.2 AEO60886.1 - 0.043 14.0 2.0 0.053 13.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3796) ER_lumen_recept PF00810.13 AEO60886.1 - 0.049 14.1 0.3 0.049 14.1 0.2 2.2 3 0 0 3 3 3 0 ER lumen protein retaining receptor Pox_A14 PF05767.7 AEO60886.1 - 0.084 12.8 1.0 0.21 11.5 0.0 2.1 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 DUF1129 PF06570.6 AEO60886.1 - 0.085 12.1 1.2 0.2 10.9 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF4131 PF13567.1 AEO60886.1 - 1.5 8.1 16.2 1.3 8.4 0.2 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4131) R3H-assoc PF13902.1 AEO60888.1 - 8.3e-22 77.5 6.3 8.3e-22 77.5 4.4 2.1 3 0 0 3 3 3 1 R3H-associated N-terminal domain R3H PF01424.17 AEO60888.1 - 0.0018 17.9 0.0 0.0043 16.7 0.0 1.7 1 0 0 1 1 1 1 R3H domain Sporozoite_P67 PF05642.6 AEO60888.1 - 0.019 12.8 2.8 0.026 12.4 1.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Presenilin PF01080.12 AEO60888.1 - 1.6 7.4 3.2 2.4 6.8 2.2 1.2 1 0 0 1 1 1 0 Presenilin Ribosomal_60s PF00428.14 AEO60888.1 - 2.8 8.4 5.2 5 7.5 0.4 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein UCR_TM PF02921.9 AEO60890.1 - 1.8e-18 66.5 0.7 3.5e-18 65.5 0.5 1.5 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 AEO60890.1 - 7.5e-18 63.8 0.0 1.2e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain DUF2516 PF10724.4 AEO60890.1 - 0.091 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2516) MMS1_N PF10433.4 AEO60891.1 - 1.2e-91 307.3 0.0 1.6e-91 306.9 0.0 1.1 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 AEO60891.1 - 1.3e-60 205.1 0.0 1.5e-59 201.7 0.0 2.2 2 0 0 2 2 2 1 CPSF A subunit region PQQ_3 PF13570.1 AEO60891.1 - 0.087 13.1 0.7 36 4.8 0.0 4.1 4 0 0 4 4 4 0 PQQ-like domain Aminotran_1_2 PF00155.16 AEO60892.1 - 2.7e-06 26.6 0.0 5.2e-05 22.3 0.0 2.2 2 1 1 3 3 3 2 Aminotransferase class I and II Cupin_7 PF12973.2 AEO60892.1 - 0.047 13.5 0.0 1.8 8.4 0.0 2.8 3 0 0 3 3 3 0 ChrR Cupin-like domain Adeno_PIX PF03955.9 AEO60893.1 - 0.019 15.4 5.0 0.019 15.4 3.5 1.8 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) DJ-1_PfpI PF01965.19 AEO60895.1 - 1.3e-28 99.3 0.4 3e-28 98.1 0.3 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 AEO60895.1 - 5e-21 73.9 0.6 1.7e-20 72.2 0.1 2.1 2 0 0 2 2 2 1 N-terminal domain of DJ-1_PfpI family DUF4066 PF13278.1 AEO60895.1 - 0.0014 17.8 0.1 0.028 13.6 0.0 2.3 2 1 0 2 2 2 1 Putative amidotransferase Macoilin PF09726.4 AEO60896.1 - 2 6.5 2.9 2.5 6.3 2.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Cellulase PF00150.13 AEO60897.1 - 1.1e-24 87.1 0.2 1.4e-24 86.7 0.2 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase-like PF12876.2 AEO60897.1 - 3.9e-06 27.2 0.0 9e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_2_C PF02836.12 AEO60897.1 - 0.00053 18.9 0.0 0.0013 17.6 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.10 AEO60897.1 - 0.028 13.5 0.1 0.072 12.1 0.1 1.6 2 0 0 2 2 2 0 Beta-galactosidase Ion_trans PF00520.26 AEO60898.1 - 3.7e-07 29.5 19.4 5e-07 29.1 10.0 3.1 3 1 0 3 3 3 1 Ion transport protein PKD_channel PF08016.7 AEO60898.1 - 5e-05 21.9 10.4 0.00068 18.1 0.5 2.2 1 1 1 2 2 2 2 Polycystin cation channel Mto2_bdg PF12808.2 AEO60898.1 - 0.015 15.3 0.0 0.031 14.3 0.0 1.5 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF3814 PF12769.2 AEO60898.1 - 0.043 13.9 0.1 0.12 12.5 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3814) zf-C2H2_4 PF13894.1 AEO60899.1 - 0.0014 18.7 11.0 0.47 10.9 0.5 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 AEO60899.1 - 0.3 11.2 1.2 21 5.3 0.0 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 AEO60899.1 - 1.9 8.7 5.8 21 5.5 0.3 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Acyl_transf_3 PF01757.17 AEO60900.1 - 1.4e-29 103.0 30.6 2.2e-29 102.3 21.2 1.4 1 0 0 1 1 1 1 Acyltransferase family Gly_transf_sug PF04488.10 AEO60901.1 - 1.9e-11 44.2 0.0 1.9e-11 44.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif AAA_23 PF13476.1 AEO60901.1 - 0.0014 18.9 14.3 0.0023 18.2 9.9 1.4 1 0 0 1 1 1 1 AAA domain SprA-related PF12118.3 AEO60901.1 - 0.099 11.9 25.7 0.15 11.3 17.8 1.2 1 0 0 1 1 1 0 SprA-related family CAF-1_p150 PF11600.3 AEO60901.1 - 0.16 11.3 57.4 0.22 10.8 39.8 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal GAGA_bind PF06217.7 AEO60901.1 - 0.95 9.3 18.7 1.7 8.5 13.0 1.5 1 0 0 1 1 1 0 GAGA binding protein-like family NARP1 PF12569.3 AEO60901.1 - 4.9 5.7 36.3 8.7 4.9 25.1 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF2413 PF10310.4 AEO60901.1 - 7.7 5.2 36.3 11 4.7 25.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Asp-B-Hydro_N PF05279.6 AEO60901.1 - 8.1 6.2 34.1 13 5.5 23.6 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Oxidored_FMN PF00724.15 AEO60902.1 - 2.6e-84 283.1 0.0 3e-84 282.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.19 AEO60902.1 - 0.053 12.7 0.1 0.25 10.5 0.0 2.1 2 1 0 2 2 2 0 Xylose isomerase-like TIM barrel Ribosomal_60s PF00428.14 AEO60903.1 - 0.033 14.5 10.9 0.059 13.7 7.6 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF1682 PF07946.9 AEO60903.1 - 0.64 8.8 5.2 0.89 8.3 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) CAP59_mtransfer PF11735.3 AEO60904.1 - 1.6e-89 299.2 0.0 2.2e-89 298.8 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 AAA_28 PF13521.1 AEO60905.1 - 1.8e-28 99.5 0.0 2.1e-28 99.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AEO60905.1 - 0.00017 21.6 0.0 0.00025 21.1 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 AEO60905.1 - 0.0024 18.6 0.2 0.0054 17.5 0.2 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AEO60905.1 - 0.0091 16.3 0.0 0.017 15.3 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_32 PF13654.1 AEO60905.1 - 0.045 12.4 0.0 0.08 11.5 0.0 1.4 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 AEO60905.1 - 0.14 12.6 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein HD_3 PF13023.1 AEO60906.1 - 3.1e-47 160.3 0.1 3.8e-47 160.1 0.1 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.17 AEO60906.1 - 0.043 13.8 0.0 0.096 12.7 0.0 1.6 1 1 0 1 1 1 0 HD domain HD PF01966.17 AEO60908.1 - 1.3e-06 28.4 0.0 2.4e-06 27.5 0.0 1.5 2 0 0 2 2 2 1 HD domain Glyco_hydro_75 PF07335.6 AEO60909.1 - 8.2e-46 155.7 0.4 1.6e-45 154.8 0.3 1.5 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 Nodulin_late PF07127.6 AEO60909.1 - 8.4 6.6 6.7 19 5.4 4.7 1.6 1 0 0 1 1 1 0 Late nodulin protein Nucleoporin_C PF03177.9 AEO60910.1 - 2.7e-142 475.3 4.7 3.4e-142 474.9 3.2 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 AEO60910.1 - 1.3e-93 314.0 0.1 1.7e-93 313.6 0.1 1.1 1 0 0 1 1 1 1 Nup133 N terminal like adh_short PF00106.20 AEO60911.1 - 2.7e-23 82.7 0.0 3.7e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO60911.1 - 1.7e-12 47.6 0.0 2.4e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO60911.1 - 9.9e-08 31.8 0.0 1.9e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 AEO60911.1 - 0.00095 19.2 0.1 0.0021 18.0 0.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 AEO60911.1 - 0.087 11.7 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 AEO60911.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Erg28 PF03694.8 AEO60912.1 - 9.4e-45 151.1 0.2 1.1e-44 150.9 0.1 1.1 1 0 0 1 1 1 1 Erg28 like protein GalP_UDP_transf PF01087.17 AEO60913.1 - 5.1e-71 238.5 0.5 9.3e-70 234.3 0.2 2.2 2 1 1 3 3 3 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 AEO60913.1 - 3.6e-57 192.5 0.0 7.5e-57 191.5 0.0 1.4 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.18 AEO60913.1 - 0.0035 17.8 0.0 0.023 15.2 0.0 2.1 2 1 0 2 2 2 1 HIT domain SWIRM PF04433.12 AEO60914.1 - 9.6e-14 51.2 0.0 2.9e-13 49.7 0.0 1.9 1 0 0 1 1 1 1 SWIRM domain ZZ PF00569.12 AEO60914.1 - 2.8e-10 39.5 5.9 5.2e-10 38.7 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 AEO60914.1 - 2.3e-07 30.7 0.0 7.3e-07 29.1 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain SHOCT PF09851.4 AEO60914.1 - 0.017 14.6 0.5 0.063 12.7 0.4 2.0 1 0 0 1 1 1 0 Short C-terminal domain zf-C3HC4_2 PF13923.1 AEO60914.1 - 0.15 12.1 2.5 0.36 10.8 1.7 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) adh_short PF00106.20 AEO60915.1 - 1.3e-11 44.7 1.1 2.8e-10 40.3 0.5 2.4 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 AEO60915.1 - 0.00026 20.7 0.2 0.00063 19.4 0.1 1.7 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 AEO60915.1 - 0.0084 16.1 0.0 0.022 14.7 0.0 1.7 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 AEO60915.1 - 0.062 12.7 0.0 0.48 9.8 0.0 2.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Mg_trans_NIPA PF05653.9 AEO60916.1 - 1.4e-89 300.0 22.6 2e-89 299.5 15.6 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 AEO60916.1 - 6.1e-08 32.8 5.5 6.1e-08 32.8 3.8 3.2 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 AEO60916.1 - 3.5e-06 27.0 8.3 3.5e-06 27.0 5.7 3.1 2 1 1 3 3 3 1 EamA-like transporter family DUF914 PF06027.7 AEO60916.1 - 0.00094 18.1 2.1 0.00094 18.1 1.5 2.1 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) CDC45 PF02724.9 AEO60916.1 - 0.47 8.4 8.4 0.71 7.8 5.9 1.3 1 0 0 1 1 1 0 CDC45-like protein TPR_11 PF13414.1 AEO60917.1 - 7.9e-09 35.0 1.2 1.5e-08 34.1 0.8 1.5 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 AEO60917.1 - 2.6e-06 26.9 0.4 0.17 11.8 0.8 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 AEO60917.1 - 0.00024 20.5 0.1 0.06 12.9 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 AEO60917.1 - 0.00056 20.5 3.1 0.00056 20.5 2.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat U-box PF04564.10 AEO60917.1 - 0.11 12.4 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 U-box domain TPR_17 PF13431.1 AEO60917.1 - 0.14 12.3 0.3 0.55 10.5 0.1 2.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 AEO60917.1 - 0.57 10.9 0.0 0.57 10.9 0.0 3.6 4 1 1 5 5 5 0 Tetratricopeptide repeat Ribosomal_L19e PF01280.15 AEO60917.1 - 1.9 8.2 6.0 3.1 7.5 4.2 1.2 1 0 0 1 1 1 0 Ribosomal protein L19e SH3_9 PF14604.1 AEO60919.1 - 5.5e-10 38.6 0.0 8.7e-10 38.0 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 AEO60919.1 - 1.9e-05 23.9 0.0 3e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 AEO60919.1 - 0.00019 20.8 0.0 0.00036 19.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Podoplanin PF05808.6 AEO60919.1 - 0.0074 15.8 0.3 0.016 14.8 0.2 1.5 1 0 0 1 1 1 1 Podoplanin Herpes_gE PF02480.11 AEO60919.1 - 0.028 12.7 0.1 0.049 11.8 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Gar1 PF04410.9 AEO60920.1 - 1.5e-49 167.4 0.2 1.5e-49 167.4 0.1 2.5 3 0 0 3 3 3 1 Gar1/Naf1 RNA binding region Glyco_transf_22 PF03901.12 AEO60921.1 - 8.5e-89 298.4 16.0 9.9e-89 298.2 11.1 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family F-box-like PF12937.2 AEO60923.1 - 0.004 16.8 0.0 0.0067 16.1 0.0 1.4 1 0 0 1 1 1 1 F-box-like DUF805 PF05656.9 AEO60923.1 - 0.16 11.8 2.1 0.21 11.3 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF805) Exo5 PF09810.4 AEO60924.1 - 6.9e-115 383.6 0.3 1.3e-114 382.8 0.2 1.4 1 1 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.2 AEO60924.1 - 0.00061 19.2 2.8 0.034 13.5 1.9 3.0 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily CDC45 PF02724.9 AEO60924.1 - 0.42 8.5 2.5 1.1 7.2 1.7 1.7 1 0 0 1 1 1 0 CDC45-like protein tRNA-synt_2b PF00587.20 AEO60925.1 - 1e-22 80.5 0.0 1.4e-21 76.8 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) ProRS-C_1 PF09180.6 AEO60925.1 - 9.6e-22 76.6 0.3 2.1e-21 75.6 0.2 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.15 AEO60925.1 - 5.1e-18 64.7 0.0 1.1e-17 63.7 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain Cpn60_TCP1 PF00118.19 AEO60926.1 - 3.1e-144 481.2 11.8 3.5e-144 481.0 8.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_int_SAM_1 PF02899.12 AEO60926.1 - 0.15 12.2 0.0 0.78 9.9 0.0 2.1 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Acetyltransf_7 PF13508.1 AEO60927.1 - 5.6e-07 29.6 0.0 3e-06 27.2 0.0 2.1 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 AEO60927.1 - 1.8e-05 24.5 0.1 6.8e-05 22.7 0.0 2.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 AEO60927.1 - 3.5e-05 23.7 0.0 0.00015 21.7 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.1 AEO60927.1 - 0.022 14.6 0.0 0.052 13.4 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase AFG1_ATPase PF03969.11 AEO60928.1 - 1.1e-92 310.6 0.0 2.6e-87 292.9 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 AEO60928.1 - 1.5e-05 25.0 1.1 0.026 14.4 0.0 3.1 2 1 0 3 3 3 2 AAA ATPase domain AAA_14 PF13173.1 AEO60928.1 - 0.00099 19.0 0.0 0.002 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 AEO60928.1 - 0.0018 17.9 0.0 0.0056 16.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.24 AEO60928.1 - 0.0026 17.9 0.1 0.031 14.4 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AEO60928.1 - 0.0052 16.9 0.0 0.023 14.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain Bac_DnaA PF00308.13 AEO60928.1 - 0.016 14.8 0.1 0.49 10.0 0.1 2.7 2 1 0 2 2 2 0 Bacterial dnaA protein Sigma54_activ_2 PF14532.1 AEO60928.1 - 0.017 15.1 0.1 0.17 11.9 0.0 2.6 3 1 0 3 3 3 0 Sigma-54 interaction domain RNA_helicase PF00910.17 AEO60928.1 - 0.037 14.2 0.1 0.15 12.2 0.0 2.2 2 1 0 2 2 2 0 RNA helicase NACHT PF05729.7 AEO60928.1 - 0.045 13.4 0.1 0.2 11.3 0.0 2.2 2 1 0 2 2 2 0 NACHT domain Peptidase_M28 PF04389.12 AEO60929.1 - 6.1e-25 87.9 0.1 9.7e-25 87.3 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 AEO60929.1 - 1.9e-05 24.2 0.0 3.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 PLDc_2 PF13091.1 AEO60930.1 - 3.6e-17 62.2 0.0 5.5e-08 32.6 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 AEO60930.1 - 0.031 14.0 0.0 3.3 7.6 0.0 2.5 2 0 0 2 2 2 0 Phospholipase D Active site motif Regulator_TrmB PF11495.3 AEO60930.1 - 0.16 10.8 0.1 15 4.4 0.1 2.8 3 0 0 3 3 3 0 Archaeal transcriptional regulator TrmB NUC153 PF08159.7 AEO60932.1 - 2.8e-14 52.3 0.9 2.8e-14 52.3 0.7 3.5 3 0 0 3 3 3 1 NUC153 domain TTL PF03133.10 AEO60933.1 - 1.2e-32 112.9 0.0 4.2e-31 107.9 0.0 2.1 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 AEO60933.1 - 0.00019 20.3 0.0 0.00032 19.5 0.0 1.3 1 0 0 1 1 1 1 YheC/D like ATP-grasp CENP-T PF15511.1 AEO60933.1 - 0.003 16.8 3.7 0.003 16.8 2.6 1.4 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T CDC45 PF02724.9 AEO60933.1 - 0.012 13.7 7.9 0.019 13.0 5.5 1.2 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.6 AEO60933.1 - 0.028 12.5 6.0 0.049 11.7 4.2 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 ATP-grasp_4 PF13535.1 AEO60933.1 - 0.033 13.9 0.9 3.2 7.4 0.0 2.6 2 0 0 2 2 2 0 ATP-grasp domain eIF-3c_N PF05470.7 AEO60933.1 - 0.048 11.7 0.5 0.062 11.3 0.3 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Dala_Dala_lig_C PF07478.8 AEO60933.1 - 0.064 12.6 0.0 0.46 9.8 0.0 2.0 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus Sigma70_ner PF04546.8 AEO60933.1 - 0.099 12.2 14.5 0.16 11.5 7.4 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region YL1 PF05764.8 AEO60933.1 - 0.11 12.0 10.2 0.062 12.9 4.9 1.9 2 0 0 2 2 2 0 YL1 nuclear protein DUF2722 PF10846.3 AEO60933.1 - 0.13 11.2 4.3 0.19 10.7 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Vfa1 PF08432.5 AEO60933.1 - 0.15 12.0 4.9 0.38 10.7 3.4 1.6 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Daxx PF03344.10 AEO60933.1 - 0.4 9.1 17.5 0.024 13.1 7.7 1.8 2 0 0 2 2 2 0 Daxx Family Sporozoite_P67 PF05642.6 AEO60933.1 - 0.4 8.4 6.9 0.59 7.9 4.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.7 AEO60933.1 - 0.57 8.0 19.8 0.0039 15.1 8.0 1.5 2 0 0 2 2 2 0 Nop14-like family SDA1 PF05285.7 AEO60933.1 - 1.1 8.4 18.2 0.049 12.9 6.8 2.1 2 0 0 2 2 2 0 SDA1 CobT PF06213.7 AEO60933.1 - 1.6 7.7 26.4 0.04 13.0 13.5 1.7 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT FAM176 PF14851.1 AEO60933.1 - 4.7 6.8 9.9 0.82 9.3 3.4 2.2 3 0 0 3 3 3 0 FAM176 family Glyco_hydro_62 PF03664.8 AEO60934.1 - 2.1e-140 466.4 6.8 2.5e-140 466.2 4.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 CBM_1 PF00734.13 AEO60934.1 - 1.5e-14 53.3 14.3 3.4e-14 52.1 9.9 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Toxin_7 PF05980.7 AEO60934.1 - 0.19 11.7 1.2 0.38 10.8 0.8 1.5 1 0 0 1 1 1 0 Toxin 7 DUF4131 PF13567.1 AEO60936.1 - 0.091 12.1 0.5 0.094 12.1 0.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF1948 PF09185.5 AEO60936.1 - 0.13 11.8 0.4 0.15 11.7 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1948) Ubie_methyltran PF01209.13 AEO60937.1 - 1.8e-11 43.6 0.0 2.8e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 AEO60937.1 - 3.1e-11 43.6 0.0 9e-11 42.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO60937.1 - 5.2e-07 30.0 0.0 1.1e-06 29.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO60937.1 - 1.2e-06 28.1 0.0 2.1e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO60937.1 - 7.6e-06 25.9 0.0 1.7e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO60937.1 - 0.0001 22.6 0.0 0.00025 21.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO60937.1 - 0.00047 19.9 0.0 0.00076 19.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO60937.1 - 0.00099 19.6 0.0 0.0024 18.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain FAR1 PF03101.10 AEO60938.1 - 0.0075 16.7 0.3 0.016 15.7 0.2 1.5 1 0 0 1 1 1 1 FAR1 DNA-binding domain Cyt-b5 PF00173.23 AEO60939.1 - 8.3e-15 54.3 0.1 3.2e-12 46.0 0.1 2.9 2 1 1 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain Cyclin_N PF00134.18 AEO60942.1 - 6.5e-09 35.4 0.0 1.2e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain zf-FPG_IleRS PF06827.9 AEO60942.1 - 0.059 13.0 0.1 0.13 11.9 0.1 1.6 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS HAD_2 PF13419.1 AEO60943.1 - 0.00047 20.4 0.0 0.41 10.8 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Ribosomal_60s PF00428.14 AEO60943.1 - 4.6 7.7 9.8 0.2 12.0 0.8 2.9 3 0 0 3 3 3 0 60s Acidic ribosomal protein TPR_19 PF14559.1 AEO60944.1 - 0.016 15.5 1.4 2.1 8.7 0.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 AEO60944.1 - 0.056 13.0 0.2 4.2 7.0 0.0 3.1 2 1 1 3 3 3 0 TPR repeat Apc3 PF12895.2 AEO60944.1 - 0.092 12.8 0.0 0.47 10.6 0.0 2.2 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 AEO60944.1 - 0.098 12.6 0.4 74 3.6 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Pneumo_att_G PF05539.6 AEO60944.1 - 0.45 9.8 2.9 0.89 8.8 2.0 1.5 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G DUF1720 PF08226.6 AEO60947.1 - 0.00014 21.8 46.6 0.79 9.8 10.0 4.1 1 1 2 3 3 3 3 Domain of unknown function (DUF1720) Brix PF04427.13 AEO60949.1 - 5.6e-59 199.0 0.0 7.7e-59 198.5 0.0 1.2 1 0 0 1 1 1 1 Brix domain Peptidase_S49_N PF08496.5 AEO60949.1 - 3.8 7.2 8.5 13 5.5 5.9 1.9 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DEAD PF00270.24 AEO60950.1 - 1.5e-48 164.5 0.0 3.6e-48 163.2 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO60950.1 - 9.6e-26 89.4 0.0 1.7e-25 88.6 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AEO60950.1 - 6.9e-06 26.0 0.0 3e-05 23.9 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 AEO60950.1 - 0.014 15.1 0.8 0.035 13.8 0.1 2.1 2 1 0 2 2 2 0 Part of AAA domain Flavi_DEAD PF07652.9 AEO60950.1 - 0.088 12.5 0.0 0.32 10.7 0.0 1.9 2 0 0 2 2 2 0 Flavivirus DEAD domain SASP PF00269.15 AEO60951.1 - 0.027 14.3 0.2 0.061 13.1 0.1 1.5 1 0 0 1 1 1 0 Small, acid-soluble spore proteins, alpha/beta type ATP_bind_1 PF03029.12 AEO60952.1 - 1.2e-76 257.4 0.0 1.7e-76 256.9 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 AEO60952.1 - 3.7e-07 29.7 0.1 1.5e-05 24.5 0.0 2.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 AEO60952.1 - 1.1e-05 24.3 0.0 0.062 12.0 0.0 2.3 2 0 0 2 2 2 2 ArgK protein MMR_HSR1 PF01926.18 AEO60952.1 - 8.6e-05 22.4 0.0 0.00019 21.3 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_10 PF12846.2 AEO60952.1 - 0.00012 21.5 0.5 0.00058 19.4 0.3 2.0 1 1 0 1 1 1 1 AAA-like domain AAA_22 PF13401.1 AEO60952.1 - 0.00025 21.2 0.0 0.00077 19.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain Arf PF00025.16 AEO60952.1 - 0.0005 19.3 0.0 0.23 10.6 0.0 2.8 3 0 0 3 3 3 1 ADP-ribosylation factor family AAA_17 PF13207.1 AEO60952.1 - 0.00084 20.1 1.5 0.026 15.3 0.0 2.9 2 1 0 2 2 2 1 AAA domain Miro PF08477.8 AEO60952.1 - 0.0016 18.9 0.0 1.7 9.1 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein AAA_33 PF13671.1 AEO60952.1 - 0.0017 18.2 0.0 0.0067 16.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 AEO60952.1 - 0.0054 16.3 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 AEO60952.1 - 0.013 15.1 0.0 0.039 13.6 0.0 1.7 2 0 0 2 2 1 0 NACHT domain AAA_16 PF13191.1 AEO60952.1 - 0.018 15.0 0.0 0.051 13.5 0.0 1.7 2 0 0 2 2 1 0 AAA ATPase domain NB-ARC PF00931.17 AEO60952.1 - 0.018 13.8 0.0 0.041 12.7 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain FeoB_N PF02421.13 AEO60952.1 - 0.019 14.2 0.0 0.41 9.9 0.0 2.6 3 0 0 3 3 3 0 Ferrous iron transport protein B SRP54 PF00448.17 AEO60952.1 - 0.02 14.3 0.0 0.11 11.9 0.0 2.1 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain PduV-EutP PF10662.4 AEO60952.1 - 0.024 14.1 0.0 0.37 10.2 0.0 2.6 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.12 AEO60952.1 - 0.029 14.1 0.2 0.37 10.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF87 Thymidylate_kin PF02223.12 AEO60952.1 - 0.035 13.4 0.7 0.38 10.1 0.0 2.4 2 0 0 2 2 2 0 Thymidylate kinase PRK PF00485.13 AEO60952.1 - 0.035 13.6 0.0 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family cobW PF02492.14 AEO60952.1 - 0.046 13.1 0.0 1.4 8.3 0.0 2.4 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 AEO60952.1 - 0.058 13.1 0.3 0.27 10.9 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B eIF-3c_N PF05470.7 AEO60952.1 - 0.076 11.0 4.6 0.11 10.5 3.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus AAA_23 PF13476.1 AEO60952.1 - 0.084 13.1 0.2 7.4 6.8 0.1 2.2 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 AEO60952.1 - 0.097 12.3 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 AEO60952.1 - 0.22 11.8 1.3 1.5 9.1 0.0 2.7 2 2 1 3 3 3 0 AAA domain HIT PF01230.18 AEO60953.1 - 2.3e-17 63.2 0.1 5.1e-17 62.2 0.0 1.5 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.3 AEO60953.1 - 4e-08 33.4 0.0 6.4e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 AEO60953.1 - 0.00049 19.7 0.1 0.0012 18.5 0.0 1.6 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 Gag_spuma PF03276.9 AEO60953.1 - 0.47 8.7 4.0 0.55 8.5 2.8 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Aldo_ket_red PF00248.16 AEO60954.1 - 6.6e-53 179.3 0.0 7.8e-53 179.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family ChAPs PF09295.5 AEO60955.1 - 4.1e-161 536.1 0.0 5.1e-161 535.8 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_14 PF13428.1 AEO60955.1 - 5.2e-08 32.8 3.2 0.29 11.8 0.0 5.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 AEO60955.1 - 7.4e-06 25.4 1.1 0.075 12.9 0.5 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 AEO60955.1 - 4.7e-05 23.1 0.8 0.028 14.2 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 AEO60955.1 - 4.9e-05 22.8 3.8 0.42 10.3 0.2 3.8 4 0 0 4 4 4 2 TPR repeat TPR_19 PF14559.1 AEO60955.1 - 9e-05 22.7 0.8 0.05 13.9 0.0 3.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 AEO60955.1 - 0.00015 21.3 0.1 0.89 9.4 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 AEO60955.1 - 0.00068 19.2 2.5 0.9 9.4 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 AEO60955.1 - 0.0026 17.2 0.3 1.5 8.5 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 AEO60955.1 - 0.015 16.0 4.9 3.8 8.2 0.3 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 AEO60955.1 - 0.015 15.6 0.4 31 5.3 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 AEO60955.1 - 0.019 15.1 0.9 15 5.7 0.0 3.4 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 AEO60955.1 - 0.038 13.9 0.5 5.5 7.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 AEO60956.1 - 0.0096 15.5 11.0 11 5.7 0.0 5.2 5 0 0 5 5 5 4 TPR repeat TPR_17 PF13431.1 AEO60956.1 - 0.01 15.9 0.1 12 6.3 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat UQ_con PF00179.21 AEO60957.1 - 6e-39 132.6 0.0 7.2e-39 132.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AEO60957.1 - 0.0002 21.0 0.0 0.00027 20.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 AEO60957.1 - 0.0095 15.8 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 RWD domain RabGAP-TBC PF00566.13 AEO60958.1 - 2.7e-35 121.7 0.0 1.8e-34 119.1 0.0 2.1 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF2231 PF09990.4 AEO60960.1 - 0.16 12.2 3.2 1 9.7 0.6 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) Peptidase_S24 PF00717.18 AEO60961.1 - 1.6e-07 30.8 0.0 2.3e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like BTB PF00651.26 AEO60962.1 - 4.3e-08 33.1 0.0 9.7e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Skp1_POZ PF03931.10 AEO60962.1 - 0.009 16.0 0.0 0.27 11.3 0.0 2.5 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain DUF1349 PF07081.6 AEO60963.1 - 5.7e-13 48.6 0.0 2e-10 40.3 0.0 3.0 2 1 0 2 2 2 2 Protein of unknown function (DUF1349) DUF4611 PF15387.1 AEO60963.1 - 0.035 14.2 0.0 0.061 13.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) TFIIB PF00382.14 AEO60964.1 - 1.4e-29 101.7 4.1 9.4e-15 54.1 0.4 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 AEO60964.1 - 3.2e-19 68.9 0.0 3.2e-19 68.9 0.0 4.1 4 1 1 5 5 5 1 Brf1-like TBP-binding domain Cyclin_N PF00134.18 AEO60964.1 - 0.005 16.4 0.5 0.14 11.7 0.0 2.3 1 1 1 2 2 2 1 Cyclin, N-terminal domain Ribonuc_red_lgN PF00317.16 AEO60964.1 - 0.015 15.0 1.0 1.7 8.5 0.0 2.7 2 0 0 2 2 2 0 Ribonucleotide reductase, all-alpha domain zf-CCHC PF00098.18 AEO60965.1 - 1.1e-05 25.1 3.7 1.7e-05 24.4 2.5 1.4 1 0 0 1 1 1 1 Zinc knuckle TetR PF13972.1 AEO60966.1 - 0.004 16.6 0.0 0.006 16.0 0.0 1.3 1 0 0 1 1 1 1 Bacterial transcriptional repressor Viral_P18 PF04521.8 AEO60966.1 - 1.8 7.9 4.6 33 3.9 3.2 2.1 1 1 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein DUF1936 PF09151.5 AEO60968.1 - 0.0076 15.7 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1936) Zip PF02535.17 AEO60968.1 - 0.049 12.6 0.7 0.052 12.5 0.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter PBP1_TM PF14812.1 AEO60968.1 - 0.15 12.4 3.0 0.23 11.7 2.1 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SelP_N PF04592.9 AEO60968.1 - 0.16 11.2 3.1 0.25 10.7 2.1 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF2946 PF11162.3 AEO60968.1 - 0.54 10.4 9.0 0.035 14.3 0.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2946) Ribosomal_60s PF00428.14 AEO60968.1 - 0.61 10.5 3.1 0.21 11.9 0.3 1.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein Lipase_GDSL PF00657.17 AEO60969.1 - 1.7e-17 64.0 0.6 8e-17 61.8 0.4 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 AEO60969.1 - 3.2e-14 53.4 4.0 2.1e-13 50.8 2.8 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.1 AEO60969.1 - 3.7e-08 33.2 0.0 5.2e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family E1-E2_ATPase PF00122.15 AEO60970.1 - 9.9e-20 70.5 0.0 1.7e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 AEO60970.1 - 1.2e-17 65.0 0.0 1.9e-15 57.8 0.0 3.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AEO60970.1 - 1.4e-11 44.1 0.0 4.4e-11 42.5 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 AEO60970.1 - 7.1e-11 42.6 0.1 2.4e-09 37.6 0.1 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 AEO60970.1 - 0.0066 16.0 0.0 0.022 14.3 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 AEO60970.1 - 0.027 14.6 0.2 0.12 12.5 0.0 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Vps35 PF03635.12 AEO60971.1 - 0 1031.7 0.1 0 1031.5 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 TFR_dimer PF04253.10 AEO60972.1 - 1.8e-21 76.0 0.0 3e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 AEO60972.1 - 2.1e-12 47.1 0.0 6.9e-12 45.4 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.17 AEO60972.1 - 1.4e-06 27.9 0.1 2.8e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 PA domain TENA_THI-4 PF03070.11 AEO60973.1 - 1.1e-12 48.1 0.1 1.2e-06 28.4 0.0 2.2 2 0 0 2 2 2 2 TENA/THI-4/PQQC family DUF3435 PF11917.3 AEO60975.1 - 7.1e-05 21.7 0.5 9e-05 21.3 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) DUF3723 PF12520.3 AEO60977.1 - 1.9e-41 142.1 0.0 2.4e-41 141.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) EST1_DNA_bind PF10373.4 AEO60984.1 - 8e-18 64.6 0.9 7.3e-16 58.2 0.1 2.5 1 1 1 2 2 2 2 Est1 DNA/RNA binding domain Shisa PF13908.1 AEO60984.1 - 0.34 11.0 2.7 0.18 11.9 0.1 1.8 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator ABC_tran PF00005.22 AEO60985.1 - 1.4e-31 109.5 0.0 3.2e-31 108.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 AEO60985.1 - 2.8e-18 66.3 2.8 2.7e-17 63.1 0.2 2.5 2 1 1 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 AEO60985.1 - 0.00074 18.8 0.0 0.0052 16.0 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 AEO60985.1 - 0.0015 18.5 0.0 0.073 13.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 AEO60985.1 - 0.0027 17.2 0.1 0.01 15.3 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 AEO60985.1 - 0.0092 15.1 0.0 0.028 13.6 0.0 1.8 1 1 1 2 2 2 1 Protein of unknown function, DUF258 SbcCD_C PF13558.1 AEO60985.1 - 0.014 15.2 0.7 0.12 12.3 0.1 2.7 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 AEO60985.1 - 0.019 15.0 0.0 0.062 13.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 AEO60985.1 - 0.074 12.4 0.2 0.19 11.1 0.1 1.7 1 1 0 1 1 1 0 AAA-like domain LAMTOR PF15454.1 AEO60985.1 - 0.24 11.7 0.9 0.53 10.6 0.6 1.5 1 0 0 1 1 1 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Methyltransf_23 PF13489.1 AEO60990.1 - 2.4e-10 40.3 0.0 4.4e-10 39.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO60990.1 - 7.4e-07 29.7 0.1 3.2e-06 27.6 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO60990.1 - 2.2e-06 27.3 0.1 1.8e-05 24.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 AEO60990.1 - 0.00022 20.3 0.0 0.0004 19.4 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.7 AEO60990.1 - 0.00058 20.2 0.0 0.0011 19.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO60990.1 - 0.00091 19.5 0.0 0.0022 18.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO60990.1 - 0.0041 17.5 0.0 0.0084 16.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AEO60990.1 - 0.0041 16.5 0.0 0.0068 15.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 AEO60990.1 - 0.12 12.4 0.0 0.15 12.1 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain HTH_23 PF13384.1 AEO60995.1 - 0.065 12.9 1.1 18 5.1 0.0 3.2 2 1 0 2 2 2 0 Homeodomain-like domain Pardaxin PF07425.6 AEO60995.1 - 0.44 9.9 6.4 7.4 6.0 0.4 2.8 2 0 0 2 2 2 0 Pardaxin YrhK PF14145.1 AEO60996.1 - 0.039 13.6 4.8 2.3 7.9 3.2 3.0 1 1 1 2 2 2 0 YrhK-like protein DUF2127 PF09900.4 AEO60996.1 - 0.81 9.7 6.3 2.5 8.1 4.7 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2127) zf-H2C2_2 PF13465.1 AEO60997.1 - 2.3e-10 40.2 5.7 9.3e-09 35.1 1.8 2.3 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 AEO60997.1 - 5.2e-06 26.4 9.9 0.00035 20.7 0.1 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 AEO60997.1 - 1.9e-05 24.6 10.2 0.0012 19.0 0.2 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-Di19 PF05605.7 AEO60997.1 - 0.00057 19.9 1.5 0.00076 19.5 1.0 1.2 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-TRAF PF02176.13 AEO60997.1 - 0.0011 19.2 0.2 0.0023 18.2 0.2 1.5 1 0 0 1 1 1 1 TRAF-type zinc finger Zn_Tnp_IS1595 PF12760.2 AEO60997.1 - 0.0016 18.2 0.7 0.0025 17.5 0.5 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-BED PF02892.10 AEO60997.1 - 0.0031 17.2 4.8 0.075 12.7 0.2 2.3 2 0 0 2 2 2 2 BED zinc finger Zn-ribbon_8 PF09723.5 AEO60997.1 - 0.015 15.2 0.7 2.8 7.9 0.0 2.4 2 0 0 2 2 2 0 Zinc ribbon domain Zn_Tnp_IS1 PF03811.8 AEO60997.1 - 0.016 14.6 4.0 0.016 14.6 2.8 2.0 2 1 0 2 2 2 0 InsA N-terminal domain zf-nanos PF05741.8 AEO60997.1 - 0.024 14.6 1.8 0.6 10.1 0.1 2.3 2 0 0 2 2 2 0 Nanos RNA binding domain zf-met PF12874.2 AEO60997.1 - 0.06 13.5 1.1 5.1 7.4 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type ROS_MUCR PF05443.6 AEO60997.1 - 0.076 12.7 0.0 0.088 12.5 0.0 1.1 1 0 0 1 1 1 0 ROS/MUCR transcriptional regulator protein zf-C2H2_6 PF13912.1 AEO60997.1 - 0.091 12.6 2.5 0.38 10.7 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 AEO60997.1 - 0.11 12.7 0.7 2.7 8.2 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding FdhE PF04216.7 AEO60997.1 - 0.23 11.1 1.6 0.28 10.8 1.1 1.1 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation Ogr_Delta PF04606.7 AEO60997.1 - 0.3 10.7 2.1 0.53 9.9 1.5 1.4 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger Cytochrome_C7 PF14522.1 AEO60997.1 - 0.31 10.7 4.0 0.69 9.5 2.7 1.6 1 1 0 1 1 1 0 Cytochrome c7 zf-CHY PF05495.7 AEO60997.1 - 0.37 10.9 4.9 0.29 11.3 1.1 2.0 1 1 1 2 2 2 0 CHY zinc finger Bim_N PF06773.6 AEO60998.1 - 0.11 12.2 2.4 0.28 10.9 1.7 1.7 1 0 0 1 1 1 0 Bim protein N-terminus EST1_DNA_bind PF10373.4 AEO60999.1 - 0.03 13.5 0.0 0.057 12.6 0.0 1.5 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain Myb_DNA-bind_6 PF13921.1 AEO61001.1 - 0.00011 22.1 1.1 0.53 10.4 0.4 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 AEO61001.1 - 0.0055 16.7 4.9 1.2 9.2 1.1 2.5 2 1 0 2 2 2 2 Myb-like DNA-binding domain Macoilin PF09726.4 AEO61002.1 - 0.021 13.1 2.7 0.026 12.8 1.8 1.1 1 0 0 1 1 1 0 Transmembrane protein LPP PF04728.8 AEO61004.1 - 0.15 11.8 10.2 1.5 8.6 7.1 2.4 1 1 0 1 1 1 0 Lipoprotein leucine-zipper WEMBL PF05701.6 AEO61004.1 - 0.34 9.3 8.4 0.5 8.7 5.8 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Flagellin_C PF00700.16 AEO61004.1 - 1.1 9.5 7.1 0.35 11.0 2.1 2.0 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region PAT1 PF09770.4 AEO61004.1 - 5.3 5.1 10.1 7.2 4.7 7.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-H2C2_2 PF13465.1 AEO61006.1 - 2e-20 71.9 13.7 1.6e-09 37.5 0.3 3.0 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 AEO61006.1 - 1.9e-15 56.1 16.1 1.9e-07 31.0 0.5 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AEO61006.1 - 2.1e-14 52.6 19.0 1.1e-06 28.5 1.2 3.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 AEO61006.1 - 1.5e-09 37.7 6.0 0.00086 19.3 0.4 3.1 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 AEO61006.1 - 3.6e-06 26.6 5.3 0.032 14.1 0.1 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 AEO61006.1 - 3.8e-06 26.9 3.0 0.00074 19.6 0.4 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-Di19 PF05605.7 AEO61006.1 - 0.00075 19.5 9.5 0.0035 17.4 2.3 2.4 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.6 AEO61006.1 - 0.0017 17.9 1.9 0.0017 17.9 1.3 2.4 1 1 1 2 2 2 1 GAGA factor RRN7 PF11781.3 AEO61006.1 - 0.0031 16.9 3.1 2.1 7.9 0.0 3.1 3 0 0 3 3 3 1 RNA polymerase I-specific transcription initiation factor Rrn7 C1_4 PF07975.7 AEO61006.1 - 0.0059 16.5 4.6 0.34 10.9 0.9 2.4 1 1 1 2 2 2 1 TFIIH C1-like domain C1_1 PF00130.17 AEO61006.1 - 0.0077 15.9 0.4 0.51 10.1 0.0 2.2 1 1 1 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_2 PF12756.2 AEO61006.1 - 0.0078 16.3 3.3 0.4 10.8 0.4 2.3 1 1 1 2 2 2 1 C2H2 type zinc-finger (2 copies) Prok-RING_1 PF14446.1 AEO61006.1 - 0.019 14.6 1.5 5.4 6.8 0.0 3.0 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 C1_3 PF07649.7 AEO61006.1 - 0.02 14.9 8.3 1.3 9.1 0.1 3.1 3 0 0 3 3 3 0 C1-like domain zf-CHY PF05495.7 AEO61006.1 - 0.029 14.5 4.4 0.054 13.6 3.1 1.5 1 1 0 1 1 1 0 CHY zinc finger Rpr2 PF04032.11 AEO61006.1 - 0.061 13.2 2.5 0.59 10.0 1.7 1.9 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-AN1 PF01428.11 AEO61006.1 - 0.094 12.6 6.5 2.5 8.0 0.1 3.1 2 1 0 2 2 2 0 AN1-like Zinc finger PHD PF00628.24 AEO61006.1 - 0.12 12.0 5.0 2 8.1 1.6 2.5 2 1 0 2 2 2 0 PHD-finger zf-RING_3 PF14369.1 AEO61006.1 - 0.15 12.0 7.4 5.5 7.0 0.1 2.7 2 1 0 2 2 2 0 zinc-finger zf-CHCC PF10276.4 AEO61006.1 - 0.16 11.8 0.4 0.16 11.8 0.3 2.8 3 0 0 3 3 3 0 Zinc-finger domain zf-HIT PF04438.11 AEO61006.1 - 0.17 11.5 11.4 1 9.0 0.3 3.1 3 0 0 3 3 3 0 HIT zinc finger zf-H2C2_5 PF13909.1 AEO61006.1 - 0.22 11.8 0.3 0.22 11.8 0.2 3.4 3 1 0 3 3 3 0 C2H2-type zinc-finger domain zf-BED PF02892.10 AEO61006.1 - 0.28 10.9 4.1 6.3 6.6 0.1 2.4 1 1 1 2 2 2 0 BED zinc finger Zn_ribbon_2 PF12674.2 AEO61006.1 - 0.31 11.3 1.8 0.35 11.2 1.2 1.1 1 0 0 1 1 1 0 Putative zinc ribbon domain DUF2256 PF10013.4 AEO61006.1 - 0.32 10.8 5.8 6.4 6.6 0.1 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF4379 PF14311.1 AEO61006.1 - 0.37 10.6 3.9 5.7 6.8 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4379) zf-RING_5 PF14634.1 AEO61006.1 - 0.54 10.0 7.0 12 5.6 0.1 2.8 2 1 0 2 2 2 0 zinc-RING finger domain DUF2296 PF10058.4 AEO61006.1 - 0.65 9.7 6.7 9.8 6.0 0.1 2.3 2 1 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) zf-TRAF PF02176.13 AEO61006.1 - 0.76 10.1 5.6 0.38 11.1 0.7 2.0 1 1 1 2 2 2 0 TRAF-type zinc finger zf-met2 PF12907.2 AEO61006.1 - 0.84 9.6 8.4 1 9.4 0.3 2.8 1 1 2 3 3 3 0 Zinc-binding zf-RING_2 PF13639.1 AEO61006.1 - 0.91 9.3 8.8 6.3 6.7 6.1 2.1 1 1 0 1 1 1 0 Ring finger domain Vps39_2 PF10367.4 AEO61006.1 - 1.2 9.3 3.5 20 5.4 0.0 2.8 1 1 2 3 3 3 0 Vacuolar sorting protein 39 domain 2 zf-C3HC4 PF00097.20 AEO61006.1 - 1.6 8.4 7.2 2.7e+02 1.3 5.0 2.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF629 PF04780.7 AEO61006.1 - 2 6.8 4.4 1.6 7.1 0.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-DNL PF05180.7 AEO61006.1 - 2.2 8.0 4.7 2.3 7.9 0.3 2.1 1 1 1 2 2 2 0 DNL zinc finger LIM PF00412.17 AEO61006.1 - 2.6 8.1 5.4 0.56 10.3 0.8 2.0 1 1 1 2 2 2 0 LIM domain Zn-ribbon_8 PF09723.5 AEO61006.1 - 2.7 8.0 11.2 49 3.9 2.7 3.0 1 1 1 2 2 2 0 Zinc ribbon domain DZR PF12773.2 AEO61006.1 - 4.5 7.1 9.7 1.6e+02 2.2 6.7 2.3 1 1 0 1 1 1 0 Double zinc ribbon Cys_rich_CPXG PF14255.1 AEO61006.1 - 7.5 6.4 6.5 7.8 6.4 0.1 2.9 3 0 0 3 3 3 0 Cysteine-rich CPXCG Prok-RING_4 PF14447.1 AEO61006.1 - 7.6 6.1 7.8 2 8.0 0.1 2.9 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.1 AEO61006.1 - 9.9 6.2 7.5 5.6e+02 0.6 5.2 2.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Peptidase_M15_3 PF08291.6 AEO61007.1 - 0.057 13.2 0.0 0.092 12.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase M15 BCS1_N PF08740.6 AEO61011.1 - 2e-27 96.0 0.1 3.6e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 AEO61011.1 - 1.8e-17 63.7 0.0 6e-16 58.8 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 AEO61011.1 - 0.002 18.9 0.0 0.0047 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 AEO61011.1 - 0.0044 16.1 0.0 0.01 14.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 AEO61011.1 - 0.0044 16.4 0.0 0.0085 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 AEO61011.1 - 0.035 13.8 0.0 0.12 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) KaiC PF06745.8 AEO61011.1 - 0.069 12.2 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_18 PF13238.1 AEO61011.1 - 0.095 13.0 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 AEO61011.1 - 0.12 11.7 0.0 0.28 10.5 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF3435 PF11917.3 AEO61012.1 - 9.2e-18 64.1 0.2 1.1e-17 63.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Pkinase PF00069.20 AEO61013.1 - 5.3e-14 51.9 0.0 1e-13 51.0 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain YrbL-PhoP_reg PF10707.4 AEO61013.1 - 0.018 14.4 0.0 0.035 13.4 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Glyco_tranf_2_3 PF13641.1 AEO61014.1 - 1e-08 35.3 0.8 1.7e-07 31.3 0.5 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_64 PF09258.5 AEO61014.1 - 0.0056 15.8 0.0 0.0081 15.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain bZIP_2 PF07716.10 AEO61015.1 - 3.8e-06 26.6 16.6 6.9e-06 25.7 11.5 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 AEO61015.1 - 0.0097 15.8 15.7 0.015 15.1 10.9 1.3 1 0 0 1 1 1 1 bZIP transcription factor IncA PF04156.9 AEO61015.1 - 1.5 8.4 6.7 2 7.9 4.6 1.2 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 AEO61015.1 - 4.1 6.9 8.8 1.3 8.5 4.3 1.5 2 0 0 2 2 2 0 Septum formation initiator Drf_FH1 PF06346.7 AEO61016.1 - 2.2 7.7 25.8 3.8 7.0 17.9 1.4 1 1 0 1 1 1 0 Formin Homology Region 1 Utp12 PF04003.7 AEO61018.1 - 6.6e-10 38.8 0.8 7.5e-08 32.2 0.5 2.2 1 1 0 1 1 1 1 Dip2/Utp12 Family Nop14 PF04147.7 AEO61018.1 - 1.1 7.0 23.1 1.6 6.5 16.0 1.2 1 0 0 1 1 1 0 Nop14-like family RVT_1 PF00078.22 AEO61022.1 - 0.00033 20.1 0.2 0.00035 20.0 0.2 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Guanylate_kin PF00625.16 AEO61024.1 - 5.5e-63 211.7 0.0 6.2e-63 211.5 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.1 AEO61024.1 - 2.5e-08 33.9 0.0 7e-08 32.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AEO61024.1 - 0.00015 22.0 0.1 0.00045 20.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 AEO61024.1 - 0.00017 20.8 0.0 0.00049 19.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 AEO61024.1 - 0.00077 19.6 0.0 0.0067 16.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 AEO61024.1 - 0.0049 16.7 0.0 0.0097 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AEO61024.1 - 0.0075 16.2 0.1 0.0096 15.9 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 AEO61024.1 - 0.0097 16.7 0.1 0.025 15.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 AEO61024.1 - 0.042 14.1 0.0 0.055 13.7 0.0 1.3 1 1 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.18 AEO61024.1 - 0.055 13.4 0.0 0.092 12.7 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF1895 PF08988.5 AEO61024.1 - 0.13 12.2 0.1 0.24 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1895) Sugar_tr PF00083.19 AEO61025.1 - 1.4e-60 205.1 22.3 6.2e-50 170.0 8.1 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 AEO61025.1 - 5.5e-26 91.1 21.6 2.8e-22 78.9 12.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily TBP PF00352.16 AEO61026.1 - 4.1e-55 183.1 0.0 4.2e-28 96.5 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 AEO61026.1 - 0.042 13.8 0.0 4.4 7.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3378) Ricin_B_lectin PF00652.17 AEO61028.1 - 2.4e-09 37.2 1.6 7.7e-09 35.6 1.1 1.7 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 AEO61028.1 - 4.1e-05 23.9 0.7 0.00011 22.4 0.4 1.7 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Gln-synt_C PF00120.19 AEO61030.1 - 2.7e-61 206.9 0.0 3.3e-61 206.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 AEO61030.1 - 4.5e-20 71.0 0.0 7.3e-20 70.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Abhydrolase_2 PF02230.11 AEO61031.1 - 8.5e-22 77.6 0.0 5.1e-20 71.8 0.0 2.2 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 AEO61031.1 - 5.9e-07 29.3 0.0 1.2e-06 28.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AEO61031.1 - 5.1e-06 26.5 2.8 0.016 15.0 1.2 2.6 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 AEO61031.1 - 0.00015 21.1 0.0 0.0022 17.2 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family LIP PF03583.9 AEO61031.1 - 0.00047 19.4 0.0 0.0007 18.8 0.0 1.2 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_3 PF07859.8 AEO61031.1 - 0.0012 18.4 0.0 0.91 9.0 0.0 2.3 1 1 0 2 2 2 2 alpha/beta hydrolase fold FSH1 PF03959.8 AEO61031.1 - 0.022 14.2 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) OB_NTP_bind PF07717.11 AEO61032.1 - 7.3e-28 96.6 0.0 1.3e-27 95.8 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 AEO61032.1 - 1.5e-27 95.5 0.1 3.1e-27 94.5 0.1 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 AEO61032.1 - 3.2e-12 46.1 0.0 8.4e-12 44.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 AEO61032.1 - 0.08 12.4 0.1 0.24 10.8 0.1 1.7 2 0 0 2 2 2 0 DEAD/DEAH box helicase Pmp3 PF01679.12 AEO61033.1 - 1.7e-20 72.4 5.3 2.3e-20 72.0 3.7 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Arb1 PF09692.5 AEO61034.1 - 4.5e-131 437.3 0.0 5.2e-131 437.1 0.0 1.0 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 IPK PF03770.11 AEO61035.1 - 1.5e-52 178.0 0.0 2.2e-52 177.5 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase Clp1 PF06807.9 AEO61036.1 - 1.9e-21 76.7 0.0 3.1e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 AEO61036.1 - 1.5e-05 24.6 0.0 3.1e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 AEO61036.1 - 0.011 15.2 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.1 AEO61036.1 - 0.092 12.8 0.1 0.43 10.7 0.0 2.0 2 1 0 2 2 2 0 AAA domain RecA PF00154.16 AEO61036.1 - 0.14 11.2 0.6 0.26 10.3 0.0 1.6 2 0 0 2 2 2 0 recA bacterial DNA recombination protein DUF997 PF06196.7 AEO61037.1 - 0.17 11.4 0.5 0.23 11.0 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF997) Git3 PF11710.3 AEO61038.1 - 4.2e-50 170.1 17.4 3.4e-49 167.1 12.0 2.1 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 AEO61038.1 - 7e-30 102.6 2.3 4.6e-28 96.8 0.0 2.6 2 0 0 2 2 2 2 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.16 AEO61038.1 - 5.2e-05 22.5 0.0 0.00017 20.8 0.0 1.8 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) DUF912 PF06024.7 AEO61038.1 - 3.6 7.7 4.5 9 6.4 0.0 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) GATase PF00117.23 AEO61039.1 - 8.6e-11 41.6 0.0 1.1e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 AEO61039.1 - 0.011 15.2 0.0 0.054 12.9 0.0 2.1 1 1 0 1 1 1 0 Peptidase C26 UPF0180 PF03698.8 AEO61039.1 - 0.044 13.6 0.0 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0180) HypD PF01924.11 AEO61039.1 - 0.044 12.5 0.0 0.38 9.4 0.0 1.9 2 0 0 2 2 2 0 Hydrogenase formation hypA family DHHA2 PF02833.9 AEO61040.1 - 1e-22 80.6 0.0 1.4e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 AEO61040.1 - 5.6e-10 39.0 0.0 1e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 DHH family Oligomerisation PF02410.10 AEO61041.1 - 1.2e-05 25.2 0.0 0.00016 21.6 0.0 2.2 1 1 0 1 1 1 1 Oligomerisation domain RNA_pol PF00940.14 AEO61042.1 - 9.8e-167 554.5 0.0 1.4e-166 554.0 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 AEO61042.1 - 7.1e-81 271.9 5.2 1.1e-79 268.0 2.3 2.3 2 0 0 2 2 2 2 DNA-directed RNA polymerase N-terminal tRNA_bind PF01588.15 AEO61043.1 - 1.3e-22 79.3 0.2 1.3e-21 76.2 0.2 2.2 1 1 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.1 AEO61043.1 - 3e-05 24.4 0.0 8e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 AEO61043.1 - 0.058 13.3 0.1 0.19 11.7 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Virulence_fact PF13769.1 AEO61043.1 - 0.095 12.5 2.4 0.25 11.2 1.6 1.7 1 0 0 1 1 1 0 Virulence factor SNF2_N PF00176.18 AEO61044.1 - 1.3e-71 240.8 0.2 2.6e-71 239.8 0.2 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 AEO61044.1 - 2.3e-16 59.4 0.1 9e-16 57.5 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AEO61044.1 - 2.8e-06 27.3 0.1 1.3e-05 25.0 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Glycos_transf_2 PF00535.21 AEO61044.1 - 0.16 11.6 0.6 0.56 9.8 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 2 SAM_MT PF04445.8 AEO61045.1 - 0.015 14.4 0.1 0.023 13.8 0.1 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase BAF1_ABF1 PF04684.8 AEO61045.1 - 6 5.5 7.1 10 4.8 4.9 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Glyco_hydro_47 PF01532.15 AEO61047.1 - 2.1e-166 554.0 0.0 2.5e-166 553.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Sld5 PF05916.6 AEO61048.1 - 1.9e-23 82.8 0.0 3.3e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein ECH PF00378.15 AEO61049.1 - 2.7e-39 134.7 3.5 2.2e-28 99.0 1.7 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family Alba PF01918.16 AEO61049.1 - 0.14 11.7 0.1 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Alba PWI PF01480.12 AEO61050.1 - 2.7e-10 40.1 0.6 8.5e-10 38.6 0.4 1.9 2 0 0 2 2 2 1 PWI domain Ribosomal_S21 PF01165.15 AEO61051.1 - 1.2e-11 43.8 6.2 2e-11 43.1 4.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S21 Ndc1_Nup PF09531.5 AEO61051.1 - 6.2 5.1 6.3 9.7 4.4 4.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup HAUS6_N PF14661.1 AEO61052.1 - 1.8e-61 207.6 2.8 3.2e-61 206.8 2.0 1.3 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus DUF2857 PF11198.3 AEO61052.1 - 0.021 14.3 1.0 0.049 13.1 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2857) Glyco_hydro_72 PF03198.9 AEO61053.1 - 3.2e-120 400.8 0.3 4.3e-120 400.4 0.2 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 AEO61053.1 - 3.5e-06 26.4 0.2 1.6e-05 24.2 0.1 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Zn_clus PF00172.13 AEO61054.1 - 5e-08 32.7 8.2 7.7e-08 32.1 5.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_23 PF13489.1 AEO61056.1 - 5.1e-17 62.0 0.0 8.3e-17 61.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO61056.1 - 8.9e-14 51.3 0.0 1.7e-13 50.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO61056.1 - 8.4e-13 48.6 0.0 2e-12 47.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO61056.1 - 6.3e-12 46.0 0.0 1.1e-11 45.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO61056.1 - 5.3e-10 39.6 0.0 1.3e-09 38.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO61056.1 - 1.7e-09 37.9 0.0 5e-09 36.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO61056.1 - 3.7e-07 30.1 0.3 2.1e-06 27.7 0.2 2.1 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 AEO61056.1 - 1.3e-06 27.7 0.0 3.2e-06 26.4 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 AEO61056.1 - 0.0027 16.8 0.0 0.005 15.9 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 AEO61056.1 - 0.0039 16.5 0.0 0.0087 15.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_32 PF13679.1 AEO61056.1 - 0.0041 16.7 0.0 0.01 15.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain TPMT PF05724.6 AEO61056.1 - 0.058 12.8 0.0 0.096 12.1 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) CPSF73-100_C PF11718.3 AEO61056.1 - 0.1 11.9 0.2 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term DUF3420 PF11900.3 AEO61056.1 - 0.12 12.5 0.1 0.65 10.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3420) RrnaAD PF00398.15 AEO61056.1 - 0.12 11.3 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase His_Phos_1 PF00300.17 AEO61057.1 - 1.1e-26 93.8 0.1 1.3e-26 93.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) FTR1 PF03239.9 AEO61058.1 - 0.052 12.5 0.4 0.061 12.2 0.2 1.2 1 0 0 1 1 1 0 Iron permease FTR1 family cwf21 PF08312.7 AEO61058.1 - 0.39 10.6 2.3 2.9 7.8 1.5 2.2 1 1 0 1 1 1 0 cwf21 domain UCH PF00443.24 AEO61059.1 - 9.5e-55 185.5 0.0 1.2e-54 185.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 AEO61059.1 - 3.2e-21 76.0 0.0 7.7e-21 74.7 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 AEO61059.1 - 5.8e-12 44.8 0.2 1.4e-11 43.6 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 AEO61059.1 - 0.066 13.4 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain ARPC4 PF05856.7 AEO61060.1 - 1.2e-76 255.8 3.8 1.3e-76 255.7 2.6 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) RRM_6 PF14259.1 AEO61061.1 - 0.0099 15.8 0.0 0.024 14.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO61061.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mito_carr PF00153.22 AEO61062.1 - 8.8e-78 256.1 1.0 5.8e-26 90.0 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein PX PF00787.19 AEO61063.1 - 1.5e-24 85.9 0.0 2e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 PX domain PRP21_like_P PF12230.3 AEO61064.1 - 7.7e-59 198.9 26.1 1e-57 195.3 18.1 2.1 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 AEO61064.1 - 2e-35 120.2 0.4 5.5e-17 61.1 0.0 2.4 2 0 0 2 2 2 2 Surp module Cu-oxidase PF00394.17 AEO61064.1 - 0.078 12.8 0.0 0.35 10.7 0.0 2.1 1 1 0 1 1 1 0 Multicopper oxidase PMT PF02366.13 AEO61065.1 - 2.9e-74 249.5 19.1 5.2e-74 248.6 13.2 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 AEO61065.1 - 2.2e-57 193.6 0.6 3.2e-57 193.1 0.0 1.6 2 0 0 2 2 2 1 MIR domain TUSC2 PF15000.1 AEO61065.1 - 0.031 14.3 1.1 0.088 12.8 0.1 2.1 2 0 0 2 2 2 0 Tumour suppressor candidate 2 Sec2p PF06428.6 AEO61067.1 - 7.7e-28 96.3 22.5 1.9e-27 95.0 11.2 2.4 2 0 0 2 2 2 2 GDP/GTP exchange factor Sec2p Med9 PF07544.8 AEO61067.1 - 4.1 7.1 12.5 4.9 6.9 0.1 3.2 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 SNARE PF05739.14 AEO61070.1 - 2.6e-17 62.2 0.8 2.6e-17 62.2 0.6 2.6 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 AEO61070.1 - 1.5e-13 50.7 5.1 1.8e-13 50.5 0.2 2.6 2 1 0 2 2 2 1 Syntaxin Spc7 PF08317.6 AEO61070.1 - 0.0065 15.1 0.8 0.0065 15.1 0.6 2.0 2 0 0 2 2 2 1 Spc7 kinetochore protein MCPsignal PF00015.16 AEO61070.1 - 0.0081 15.7 1.0 0.0081 15.7 0.7 2.2 2 1 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain BLOC1_2 PF10046.4 AEO61070.1 - 0.064 13.3 2.0 1 9.5 0.1 2.7 2 2 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.7 AEO61070.1 - 0.073 12.8 0.8 2.1 8.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.7 AEO61070.1 - 0.1 12.8 1.6 20 5.5 0.0 3.2 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Aldo_ket_red PF00248.16 AEO61071.1 - 5.9e-51 172.9 0.0 7.3e-51 172.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family ADH_N PF08240.7 AEO61072.1 - 4.3e-29 100.4 0.7 9.3e-29 99.3 0.5 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AEO61072.1 - 4.1e-19 68.4 1.2 7.7e-19 67.5 0.5 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 AEO61072.1 - 0.074 12.6 0.3 0.19 11.3 0.2 1.7 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.19 AEO61072.1 - 0.08 11.7 1.4 0.11 11.2 1.0 1.2 1 0 0 1 1 1 0 FAD binding domain Methyltransf_18 PF12847.2 AEO61072.1 - 0.082 13.4 0.0 0.26 11.8 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain UDPG_MGDP_dh_N PF03721.9 AEO61072.1 - 0.094 12.0 0.8 0.17 11.2 0.6 1.5 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain adh_short PF00106.20 AEO61073.1 - 2.4e-20 73.0 0.1 3.2e-20 72.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO61073.1 - 1.1e-14 54.5 0.1 1.4e-14 54.1 0.1 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 AEO61073.1 - 6.1e-09 35.9 0.0 8.1e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 AEO61073.1 - 7.6e-05 22.4 0.4 0.00012 21.7 0.3 1.3 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 AEO61073.1 - 0.0002 20.8 0.0 0.00025 20.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 AEO61073.1 - 0.0057 16.6 1.5 0.015 15.2 0.8 1.7 1 1 1 2 2 2 1 NADH(P)-binding RmlD_sub_bind PF04321.12 AEO61073.1 - 0.012 14.4 0.0 0.022 13.6 0.0 1.3 1 1 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.8 AEO61073.1 - 0.017 14.4 0.4 0.031 13.5 0.3 1.4 1 1 0 1 1 1 0 NmrA-like family ApbA PF02558.11 AEO61073.1 - 0.07 12.5 0.1 0.1 12.0 0.0 1.4 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Polysacc_synt_2 PF02719.10 AEO61073.1 - 0.15 10.8 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Abhydrolase_5 PF12695.2 AEO61074.1 - 3.7e-11 42.9 0.0 7.4e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1100 PF06500.6 AEO61074.1 - 2.1e-10 39.7 0.0 2.7e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_6 PF12697.2 AEO61074.1 - 7.4e-10 39.0 0.1 3.3e-09 36.9 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 AEO61074.1 - 6.4e-07 28.7 0.0 1.2e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 AEO61074.1 - 6.3e-05 22.5 0.0 0.00028 20.3 0.0 1.9 1 1 0 1 1 1 1 Putative esterase Peptidase_S15 PF02129.13 AEO61074.1 - 0.0055 16.1 0.0 0.012 15.0 0.0 1.6 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase_phd PF10503.4 AEO61074.1 - 0.0057 15.9 0.0 0.012 14.8 0.0 1.6 1 0 0 1 1 1 1 Esterase PHB depolymerase DLH PF01738.13 AEO61074.1 - 0.019 14.2 0.0 0.33 10.1 0.0 2.3 1 1 0 1 1 1 0 Dienelactone hydrolase family BAAT_C PF08840.6 AEO61074.1 - 0.03 14.0 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal UPF0227 PF05728.7 AEO61074.1 - 0.068 12.8 0.0 0.21 11.2 0.0 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_3 PF07859.8 AEO61074.1 - 0.072 12.6 0.1 0.23 11.0 0.0 1.8 2 1 1 3 3 3 0 alpha/beta hydrolase fold Acetyltransf_1 PF00583.19 AEO61075.1 - 2.6e-12 46.5 0.0 3.6e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AEO61075.1 - 1.9e-09 37.5 0.0 2.8e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 AEO61075.1 - 0.0023 17.8 0.0 0.0026 17.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 AEO61075.1 - 0.0026 17.9 0.0 0.0037 17.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 AEO61075.1 - 0.062 13.4 0.0 0.088 12.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 AEO61075.1 - 0.14 11.9 0.0 1.2 8.9 0.0 2.1 2 0 0 2 2 2 0 FR47-like protein Lipase_3 PF01764.20 AEO61076.1 - 4.1e-16 58.8 0.0 3e-12 46.3 0.0 2.4 2 0 0 2 2 2 2 Lipase (class 3) AAA_25 PF13481.1 AEO61076.1 - 0.0039 16.6 0.1 0.039 13.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain OAS1_C PF10421.4 AEO61076.1 - 0.32 10.4 0.0 0.55 9.6 0.0 1.2 1 0 0 1 1 1 0 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus Glyco_hydro_43 PF04616.9 AEO61077.1 - 2.7e-30 105.4 1.3 1.4e-19 70.2 0.2 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 43 DUF2052 PF09747.4 AEO61079.1 - 1e-28 100.5 16.3 8.6e-16 58.3 6.4 2.1 1 1 1 2 2 2 2 Coiled-coil domain containing protein (DUF2052) AAA_10 PF12846.2 AEO61080.1 - 2.9e-08 33.5 0.0 0.00012 21.6 0.0 2.4 2 0 0 2 2 2 2 AAA-like domain Zot PF05707.7 AEO61080.1 - 0.0027 17.2 0.0 0.03 13.7 0.0 2.3 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) DUF87 PF01935.12 AEO61080.1 - 0.0095 15.7 0.0 0.44 10.3 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF87 Zeta_toxin PF06414.7 AEO61080.1 - 0.04 13.0 0.0 0.093 11.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.1 AEO61080.1 - 0.049 13.6 1.0 0.22 11.5 0.0 2.5 3 1 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.1 AEO61080.1 - 0.072 13.2 0.1 2 8.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.13 AEO61080.1 - 0.096 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Response_reg PF00072.19 AEO61081.1 - 6.6e-20 71.1 0.0 2.8e-13 49.8 0.0 2.3 2 0 0 2 2 2 2 Response regulator receiver domain Bot1p PF12298.3 AEO61082.1 - 1.2e-54 184.8 3.8 2.2e-54 184.0 2.6 1.5 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein Y_phosphatase3 PF13350.1 AEO61083.1 - 4.9e-39 134.2 0.0 7.1e-39 133.6 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 AEO61083.1 - 3.9e-18 65.3 0.4 1.3e-17 63.6 0.1 2.1 2 0 0 2 2 2 1 Tyrosine phosphatase family C-terminal region MARVEL PF01284.18 AEO61084.1 - 0.0019 17.9 14.2 0.011 15.5 6.1 2.0 1 1 1 2 2 2 1 Membrane-associating domain SLAC1 PF03595.12 AEO61084.1 - 0.0069 15.0 7.8 0.0091 14.6 5.4 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF2215 PF10225.4 AEO61084.1 - 0.029 13.8 1.6 0.041 13.3 1.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) zf-DHHC PF01529.15 AEO61084.1 - 0.16 11.3 5.3 1.7 8.0 3.7 2.0 1 1 0 1 1 1 0 DHHC palmitoyltransferase HlyIII PF03006.15 AEO61084.1 - 0.2 11.0 8.2 0.26 10.6 5.7 1.3 1 1 0 1 1 1 0 Haemolysin-III related Tetraspannin PF00335.15 AEO61084.1 - 0.22 10.7 6.3 0.036 13.3 1.4 1.6 1 1 0 1 1 1 0 Tetraspanin family YqhR PF11085.3 AEO61084.1 - 0.36 10.3 8.1 0.84 9.1 5.6 1.6 1 1 0 1 1 1 0 Conserved membrane protein YqhR DUF805 PF05656.9 AEO61084.1 - 0.38 10.5 9.6 0.16 11.7 3.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF805) Reticulon PF02453.12 AEO61084.1 - 0.49 9.9 7.6 0.2 11.2 2.9 1.9 1 1 1 2 2 2 0 Reticulon UPF0104 PF03706.8 AEO61084.1 - 0.83 8.8 14.2 2.2 7.4 9.8 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0104) DUF2304 PF10066.4 AEO61084.1 - 2.7 7.8 6.0 17 5.2 4.1 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2304) SH3_9 PF14604.1 AEO61086.1 - 6.5e-14 51.2 0.1 1.2e-13 50.3 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain BAR PF03114.13 AEO61086.1 - 1.3e-13 51.0 0.6 1.3e-13 51.0 0.4 1.7 2 0 0 2 2 2 1 BAR domain SH3_1 PF00018.23 AEO61086.1 - 7.6e-12 44.4 0.5 1.2e-11 43.7 0.1 1.6 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 AEO61086.1 - 1.1e-10 40.8 0.1 1.8e-10 40.1 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF2439 PF10382.4 AEO61087.1 - 2.9e-26 91.5 0.2 4.6e-26 90.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Zn_clus PF00172.13 AEO61089.1 - 0.16 11.8 8.7 0.33 10.9 6.0 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain dCMP_cyt_deam_1 PF00383.17 AEO61090.1 - 3.6e-21 74.7 0.1 1.3e-20 72.8 0.0 1.9 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 AEO61090.1 - 0.013 15.3 0.0 0.18 11.6 0.0 2.6 2 0 0 2 2 2 0 Bd3614-like deaminase GFA PF04828.9 AEO61091.1 - 2e-18 66.0 11.7 1.8e-09 37.4 2.0 3.8 3 1 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme BUD22 PF09073.5 AEO61091.1 - 0.14 11.2 7.8 0.22 10.5 5.4 1.2 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.9 AEO61091.1 - 4 5.3 8.5 0.18 9.8 1.0 1.8 2 0 0 2 2 2 0 CDC45-like protein Xan_ur_permease PF00860.15 AEO61092.1 - 3e-24 85.2 29.8 3.7e-22 78.3 20.7 2.7 1 1 0 1 1 1 1 Permease family Sulfate_transp PF00916.15 AEO61092.1 - 0.00028 19.9 4.0 0.00042 19.4 1.8 2.0 1 1 0 1 1 1 1 Sulfate transporter family Peptidase_S9 PF00326.16 AEO61094.1 - 7.3e-08 31.8 0.1 3.5e-07 29.6 0.1 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase_phd PF10503.4 AEO61094.1 - 4e-06 26.2 0.3 7.3e-06 25.3 0.2 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_5 PF12695.2 AEO61094.1 - 8.5e-06 25.5 0.1 1.1e-05 25.2 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AEO61094.1 - 0.00011 22.1 0.5 0.0053 16.6 0.0 2.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 AEO61094.1 - 0.0026 17.2 0.0 0.0041 16.5 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase AXE1 PF05448.7 AEO61094.1 - 0.0068 14.9 0.0 0.011 14.3 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Esterase PF00756.15 AEO61094.1 - 0.0071 15.8 0.1 0.039 13.3 0.0 1.9 1 1 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.15 AEO61094.1 - 0.01 15.3 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold MLTD_N PF06474.7 AEO61094.1 - 0.011 15.8 0.8 0.011 15.8 0.5 2.1 2 0 0 2 2 2 0 MltD lipid attachment motif LIP PF03583.9 AEO61094.1 - 0.015 14.4 0.0 0.034 13.3 0.0 1.6 1 1 0 1 1 1 0 Secretory lipase WD40 PF00400.27 AEO61095.1 - 1.1e-06 28.3 0.0 0.00071 19.3 0.0 3.6 3 0 0 3 3 3 1 WD domain, G-beta repeat eIF2A PF08662.6 AEO61095.1 - 0.00043 20.0 0.0 0.001 18.8 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A DUF2296 PF10058.4 AEO61096.1 - 5e-19 67.7 0.1 8.9e-19 66.9 0.1 1.4 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) DUF2157 PF09925.4 AEO61096.1 - 0.063 12.8 0.2 0.097 12.2 0.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) DUF2839 PF10999.3 AEO61096.1 - 0.12 12.4 1.0 0.26 11.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) DUF3040 PF11239.3 AEO61096.1 - 0.15 12.1 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) MIP-T3 PF10243.4 AEO61097.1 - 2.5 6.4 7.0 3.4 6.0 4.8 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 MIP-T3 PF10243.4 AEO61098.1 - 2.8 6.3 29.3 4.1 5.7 20.3 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 HTH_Tnp_Tc3_1 PF11427.3 AEO61100.1 - 0.19 11.3 1.4 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 Tc3 transposase HLH PF00010.21 AEO61104.1 - 1.5e-17 62.9 0.0 2.9e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain BAF1_ABF1 PF04684.8 AEO61104.1 - 0.0035 16.2 1.7 0.0048 15.7 1.2 1.1 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor bZIP_1 PF00170.16 AEO61104.1 - 0.015 15.2 0.4 0.13 12.2 0.1 2.4 2 0 0 2 2 2 0 bZIP transcription factor TFIIA PF03153.8 AEO61104.1 - 0.37 10.6 15.5 0.48 10.2 10.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SCIMP PF15050.1 AEO61104.1 - 0.56 10.1 3.0 0.64 9.9 1.2 1.7 2 0 0 2 2 2 0 SCIMP protein Macoilin PF09726.4 AEO61104.1 - 3.1 5.9 8.1 4.1 5.5 5.6 1.1 1 0 0 1 1 1 0 Transmembrane protein CD99L2 PF12301.3 AEO61104.1 - 6.2 6.4 7.6 1.8 8.2 0.3 2.2 1 1 0 2 2 2 0 CD99 antigen like protein 2 RR_TM4-6 PF06459.7 AEO61104.1 - 6.9 6.4 6.9 9.4 6.0 4.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF572 PF04502.8 AEO61104.1 - 9.6 5.3 12.1 13 4.8 8.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DOMON PF03351.12 AEO61106.1 - 0.0098 15.8 0.1 0.017 15.0 0.0 1.3 1 0 0 1 1 1 1 DOMON domain DUF169 PF02596.10 AEO61106.1 - 0.19 11.0 0.3 2.9 7.2 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised ArCR, COG2043 LRR_7 PF13504.1 AEO61107.1 - 0.78 10.2 4.9 71 4.3 0.5 4.4 3 1 1 4 4 4 0 Leucine rich repeat p450 PF00067.17 AEO61110.1 - 2.2e-71 240.7 0.0 2.8e-71 240.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Acetyltransf_7 PF13508.1 AEO61111.1 - 3.5e-08 33.4 0.3 7.3e-08 32.4 0.2 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 AEO61111.1 - 1.2e-07 31.6 1.1 8.4e-07 28.9 0.2 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.5 AEO61111.1 - 0.0027 17.4 0.0 0.016 14.9 0.0 2.0 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.1 AEO61111.1 - 0.014 15.5 0.4 0.094 12.8 0.1 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Pkinase PF00069.20 AEO61113.1 - 1.7e-15 56.8 0.0 2.3e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO61113.1 - 1.8e-14 53.4 0.0 2e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 AEO61113.1 - 0.067 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 AEO61113.1 - 0.16 10.8 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like XYPPX PF02162.12 AEO61114.1 - 0.00034 20.1 82.2 0.046 13.3 15.6 4.6 2 1 1 3 3 3 1 XYPPX repeat (two copies) CYSTM PF12734.2 AEO61114.1 - 0.0017 18.3 59.0 1.2e+04 -3.6 40.9 4.3 1 1 0 1 1 1 0 Cysteine-rich TM module stress tolerance Pro-rich PF15240.1 AEO61114.1 - 0.011 15.8 19.4 0.014 15.4 13.5 1.2 1 0 0 1 1 1 0 Proline-rich PAT1 PF09770.4 AEO61114.1 - 3.5 5.7 7.6 3.7 5.6 5.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 rve PF00665.21 AEO61115.1 - 0.00067 19.7 0.0 0.00082 19.4 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain Cupin_2 PF07883.6 AEO61116.1 - 0.00045 19.6 0.0 0.0048 16.3 0.0 2.4 2 0 0 2 2 2 1 Cupin domain Myc_N PF01056.13 AEO61116.1 - 0.025 13.7 1.1 0.034 13.3 0.8 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Dala_Dala_lig_C PF07478.8 AEO61117.1 - 9.5e-24 83.9 0.0 4.6e-23 81.6 0.0 1.9 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_4 PF13535.1 AEO61117.1 - 7.5e-13 48.6 0.0 5e-10 39.4 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 AEO61117.1 - 6.4e-05 21.8 0.0 0.13 10.9 0.0 2.7 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 AEO61117.1 - 0.0015 18.4 0.0 0.0024 17.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 AEO61117.1 - 0.01 15.4 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DUF1962 PF09227.5 AEO61118.1 - 8.3e-39 131.4 19.2 1e-38 131.1 13.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1962) JTB PF05439.7 AEO61118.1 - 0.37 10.5 2.2 0.54 10.0 1.5 1.3 1 0 0 1 1 1 0 Jumping translocation breakpoint protein (JTB) Pkinase PF00069.20 AEO61119.1 - 7e-20 71.2 0.0 1e-19 70.7 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO61119.1 - 2.6e-15 56.1 0.0 3.5e-15 55.7 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 AEO61119.1 - 9.8e-07 28.0 0.0 1.4e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AEO61119.1 - 0.061 13.0 0.1 0.11 12.1 0.1 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 AEO61119.1 - 0.16 11.2 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Mito_carr PF00153.22 AEO61120.1 - 3.6e-67 222.1 3.4 6.6e-22 77.0 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2650 PF10853.3 AEO61121.1 - 9.6 5.7 6.7 1.3 8.5 1.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2650) RVT_1 PF00078.22 AEO61122.1 - 0.0021 17.4 0.6 0.0022 17.4 0.4 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ycf54 PF10674.4 AEO61122.1 - 0.043 13.9 0.3 0.068 13.2 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2488) DUF3834 PF12916.2 AEO61122.1 - 0.17 10.8 0.8 0.2 10.6 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3834) GST_N_3 PF13417.1 AEO61124.1 - 1.5e-19 69.9 0.1 3.7e-19 68.7 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 AEO61124.1 - 8.2e-16 57.7 0.0 1.5e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 AEO61124.1 - 4.9e-12 45.8 0.0 9.2e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 AEO61124.1 - 1.1e-06 28.3 0.1 1.6e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 AEO61124.1 - 0.00027 20.8 0.0 0.00045 20.1 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_C PF00043.20 AEO61124.1 - 0.002 18.0 0.1 0.0046 16.9 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 AEO61124.1 - 0.067 13.6 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Pex16 PF08610.5 AEO61125.1 - 2.5e-101 339.0 0.0 4.2e-100 335.0 0.0 1.9 1 1 0 1 1 1 1 Peroxisomal membrane protein (Pex16) DUF1183 PF06682.7 AEO61125.1 - 0.0087 15.7 1.2 0.014 15.0 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) BUD22 PF09073.5 AEO61125.1 - 0.1 11.6 1.2 0.14 11.1 0.8 1.1 1 0 0 1 1 1 0 BUD22 GMC_oxred_N PF00732.14 AEO61126.1 - 9.6e-75 251.4 0.0 1.3e-74 251.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 AEO61126.1 - 1.4e-36 125.9 0.1 4e-36 124.4 0.0 1.8 1 1 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 AEO61126.1 - 8.7e-08 31.4 0.1 0.012 14.5 0.0 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 AEO61126.1 - 0.0028 16.6 0.1 0.0053 15.7 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 AEO61126.1 - 0.0081 15.0 0.2 2.4 6.9 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain GIDA PF01134.17 AEO61126.1 - 0.064 12.0 0.1 2.7 6.7 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 AEO61126.1 - 0.068 13.2 0.0 16 5.4 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 AEO61126.1 - 0.08 12.0 0.1 0.28 10.2 0.0 1.8 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.9 AEO61126.1 - 0.27 9.6 0.3 4.8 5.5 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein bZIP_2 PF07716.10 AEO61127.1 - 6e-08 32.3 16.2 1.9e-07 30.7 11.3 1.9 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 AEO61127.1 - 0.0012 18.7 13.3 0.0027 17.6 9.2 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 AEO61127.1 - 0.045 14.0 10.4 0.12 12.6 7.2 1.7 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF427 PF04248.7 AEO61128.1 - 4.9e-19 67.7 0.1 6.9e-19 67.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF427) Snf7 PF03357.16 AEO61129.1 - 3.5e-07 29.7 24.4 5.3e-07 29.1 16.9 1.2 1 0 0 1 1 1 1 Snf7 FANCI_S1 PF14675.1 AEO61129.1 - 0.032 13.5 0.4 0.57 9.4 0.0 2.0 2 0 0 2 2 2 0 FANCI solenoid 1 XLF PF09302.6 AEO61129.1 - 0.035 13.8 1.0 0.068 12.9 0.0 1.9 1 1 0 2 2 2 0 XLF (XRCC4-like factor) 3-dmu-9_3-mt PF06983.8 AEO61129.1 - 0.3 11.4 1.8 0.3 11.4 0.2 1.7 2 0 0 2 2 2 0 3-demethylubiquinone-9 3-methyltransferase Vfa1 PF08432.5 AEO61129.1 - 1.6 8.7 10.7 2.6 8.0 7.4 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Clr2 PF10383.4 AEO61129.1 - 5.6 6.9 6.1 9.1 6.2 4.3 1.3 1 0 0 1 1 1 0 Transcription-silencing protein Clr2 Spore_II_R PF09551.5 AEO61129.1 - 9.8 6.2 8.6 12 5.9 4.5 2.0 1 1 1 2 2 2 0 Stage II sporulation protein R (spore_II_R) DSHCT PF08148.7 AEO61130.1 - 4.4e-61 205.2 0.6 8e-61 204.4 0.4 1.4 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 AEO61130.1 - 6e-21 74.6 0.0 1.6e-20 73.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO61130.1 - 3.4e-06 26.8 0.3 1.5e-05 24.7 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain rRNA_proc-arch PF13234.1 AEO61130.1 - 0.00026 20.2 0.1 0.0052 15.9 0.0 2.2 2 0 0 2 2 2 1 rRNA-processing arch domain adh_short PF00106.20 AEO61131.1 - 6.1e-28 97.8 1.8 8.7e-28 97.3 1.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO61131.1 - 5.1e-18 65.7 0.0 6.2e-18 65.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO61131.1 - 2.2e-10 40.5 1.1 3.4e-10 39.8 0.8 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 AEO61131.1 - 6.6e-05 22.6 0.1 0.00011 21.8 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 AEO61131.1 - 0.00088 18.7 0.1 0.0013 18.2 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_12 PF08242.7 AEO61131.1 - 0.015 15.7 0.0 0.032 14.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 AEO61131.1 - 0.023 15.2 0.1 0.14 12.7 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain THF_DHG_CYH_C PF02882.14 AEO61131.1 - 0.028 13.5 0.0 0.07 12.2 0.0 1.7 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain UDPG_MGDP_dh_N PF03721.9 AEO61131.1 - 0.042 13.2 0.0 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_10 PF13460.1 AEO61131.1 - 0.046 13.7 1.3 0.12 12.3 0.3 2.0 1 1 0 2 2 2 0 NADH(P)-binding Polysacc_synt_2 PF02719.10 AEO61131.1 - 0.078 11.8 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 AEO61131.1 - 0.26 11.1 2.6 0.96 9.2 0.6 2.3 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ICL PF00463.16 AEO61132.1 - 4.4e-197 655.4 0.1 5e-197 655.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 AEO61132.1 - 1.7e-11 43.7 0.0 8.9e-11 41.4 0.0 2.0 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Swi3 PF07962.7 AEO61133.1 - 4.5e-29 99.9 0.2 8.4e-29 99.0 0.1 1.5 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 NADH-u_ox-rdase PF10785.4 AEO61134.1 - 2.8e-34 117.2 0.3 4.6e-34 116.5 0.2 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.2 AEO61134.1 - 4.2e-33 112.9 0.0 6.7e-33 112.2 0.0 1.3 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit F-box-like PF12937.2 AEO61136.1 - 2e-09 37.0 0.9 4.1e-09 36.0 0.6 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 AEO61136.1 - 8.9e-07 28.4 2.4 2e-06 27.2 1.7 1.6 1 0 0 1 1 1 1 F-box domain Pkinase_Tyr PF07714.12 AEO61137.1 - 0.22 10.5 0.0 0.33 9.9 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase SWIRM PF04433.12 AEO61139.1 - 4.4e-16 58.7 0.1 9.4e-15 54.5 0.0 2.1 2 0 0 2 2 2 1 SWIRM domain Sulfate_tra_GLY PF13792.1 AEO61141.1 - 0.018 14.7 0.4 0.049 13.2 0.3 1.7 1 0 0 1 1 1 0 Sulfate transporter N-terminal domain with GLY motif NfeD PF01957.13 AEO61141.1 - 6.5 6.8 7.6 3.5 7.7 0.2 3.2 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding Aldedh PF00171.17 AEO61142.1 - 7.4e-148 492.6 0.0 8.5e-148 492.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RVT_1 PF00078.22 AEO61143.1 - 2.7e-08 33.4 0.5 2.9e-08 33.3 0.4 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 AEO61144.1 - 0.00027 20.3 0.2 0.00027 20.3 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_L23 PF00276.15 AEO61144.1 - 0.21 11.5 2.6 0.23 11.3 1.8 1.2 1 0 0 1 1 1 0 Ribosomal protein L23 RVT_1 PF00078.22 AEO61145.1 - 0.00024 20.5 0.6 0.00028 20.2 0.4 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1691 PF07950.6 AEO61147.1 - 3e-39 133.3 2.9 6e-24 84.0 1.3 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) GCV_T_C PF08669.6 AEO61147.1 - 0.1 12.6 0.2 22 5.1 0.0 2.4 2 0 0 2 2 2 0 Glycine cleavage T-protein C-terminal barrel domain zf-C2H2_jaz PF12171.3 AEO61148.1 - 1.3e-06 28.4 4.4 1.9e-06 27.8 3.1 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 AEO61148.1 - 0.00044 20.3 1.0 0.00067 19.7 0.7 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 AEO61148.1 - 0.0041 17.3 0.3 0.0068 16.6 0.2 1.3 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.21 AEO61148.1 - 0.039 14.3 1.0 0.062 13.6 0.7 1.3 1 0 0 1 1 1 0 Zinc finger, C2H2 type Serglycin PF04360.7 AEO61148.1 - 0.15 11.8 0.3 0.2 11.3 0.2 1.3 1 0 0 1 1 1 0 Serglycin zf-C2H2_2 PF12756.2 AEO61148.1 - 0.16 12.1 1.5 0.23 11.5 1.1 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.7 AEO61148.1 - 0.52 10.0 2.2 0.92 9.2 1.5 1.3 1 0 0 1 1 1 0 DBF zinc finger Fungal_trans PF04082.13 AEO61149.1 - 1.3e-05 24.2 0.1 0.00013 20.9 0.0 2.5 3 0 0 3 3 3 1 Fungal specific transcription factor domain Cu_amine_oxid PF01179.15 AEO61150.1 - 8.1e-155 515.6 0.0 2.2e-129 431.7 0.0 2.0 2 0 0 2 2 2 2 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 AEO61150.1 - 1.8e-09 37.5 0.0 7.8e-09 35.5 0.0 1.9 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 AEO61150.1 - 1.5e-07 31.3 0.0 3.9e-07 30.0 0.0 1.7 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain Epimerase PF01370.16 AEO61151.1 - 1.5e-19 70.4 0.0 2e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 AEO61151.1 - 5.4e-08 31.8 0.0 7.4e-08 31.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 AEO61151.1 - 5.1e-06 25.5 0.1 1.8e-05 23.8 0.1 1.7 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 AEO61151.1 - 0.00078 19.4 2.3 0.003 17.4 1.6 1.9 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 AEO61151.1 - 0.0009 19.2 0.3 0.0049 16.8 0.2 2.2 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 AEO61151.1 - 0.011 15.0 0.0 0.1 11.8 0.1 2.0 2 0 0 2 2 2 0 NmrA-like family Glyoxalase_2 PF12681.2 AEO61152.1 - 2.8e-13 50.4 0.0 3.3e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 AEO61152.1 - 1.8e-10 40.9 0.0 3.3e-10 40.0 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Lipase_GDSL PF00657.17 AEO61153.1 - 5.4e-12 46.0 0.6 1.1e-11 45.0 0.4 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 AEO61153.1 - 1.8e-09 37.9 0.7 2.8e-09 37.3 0.5 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF169 PF02596.10 AEO61153.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised ArCR, COG2043 Prenyltrans_1 PF13243.1 AEO61153.1 - 0.14 12.1 0.1 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Prenyltransferase-like TRAM_LAG1_CLN8 PF03798.11 AEO61154.1 - 6.1e-47 159.7 15.6 9.8e-47 159.0 10.8 1.3 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 AEO61154.1 - 2.3e-19 68.6 0.0 5.4e-19 67.4 0.0 1.7 1 0 0 1 1 1 1 TRAM1-like protein RRM_1 PF00076.17 AEO61155.1 - 1.5e-16 59.8 0.1 1.4e-15 56.6 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO61155.1 - 1.9e-09 37.3 0.0 3.5e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO61155.1 - 1.1e-05 25.1 0.0 2.7e-05 23.9 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rota_VP2 PF05087.7 AEO61155.1 - 2 6.2 0.0 2 6.2 0.0 2.5 2 1 1 3 3 3 0 Rotavirus VP2 protein WD40 PF00400.27 AEO61156.1 - 1.7e-10 40.3 1.4 0.00097 18.9 0.0 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat BBE PF08031.7 AEO61156.1 - 0.18 11.7 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 Berberine and berberine like Septin PF00735.13 AEO61157.1 - 8.7e-106 353.0 0.0 1.7e-105 352.0 0.0 1.4 2 0 0 2 2 2 1 Septin Dynamin_N PF00350.18 AEO61157.1 - 6.9e-05 22.7 1.0 0.21 11.3 0.0 3.0 3 0 0 3 3 3 2 Dynamin family MMR_HSR1 PF01926.18 AEO61157.1 - 0.00066 19.6 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_17 PF13207.1 AEO61157.1 - 0.00067 20.4 1.9 0.0093 16.7 0.0 2.8 2 2 0 2 2 2 1 AAA domain DUF258 PF03193.11 AEO61157.1 - 0.0046 16.1 0.1 0.013 14.6 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 AEO61157.1 - 0.029 14.8 0.2 0.084 13.3 0.0 1.8 2 0 0 2 2 2 0 Miro-like protein AAA_24 PF13479.1 AEO61157.1 - 0.061 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 AEO61157.1 - 0.094 12.8 0.0 0.37 10.9 0.0 2.1 1 1 0 1 1 1 0 AAA domain Ribosomal_60s PF00428.14 AEO61157.1 - 0.13 12.7 6.6 0.33 11.3 4.6 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein V_ATPase_I PF01496.14 AEO61157.1 - 3.3 5.4 4.7 5 4.8 3.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Bax1-I PF01027.15 AEO61158.1 - 1e-49 168.9 27.4 1.2e-49 168.7 19.0 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Spore_YhaL PF14147.1 AEO61158.1 - 0.061 12.7 0.1 0.2 11.0 0.1 1.9 1 0 0 1 1 1 0 Sporulation protein YhaL Orbi_NS3 PF01616.11 AEO61158.1 - 0.16 10.9 0.9 1.2 8.0 0.1 2.1 2 0 0 2 2 2 0 Orbivirus NS3 DUF4407 PF14362.1 AEO61158.1 - 8.4 5.2 17.2 1.3 7.9 5.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DLIC PF05783.6 AEO61159.1 - 4.3e-35 121.3 0.0 2.1e-32 112.4 0.0 2.5 2 1 0 2 2 2 2 Dynein light intermediate chain (DLIC) Phage_tail_2 PF06199.6 AEO61159.1 - 0.053 13.5 0.1 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Phage major tail protein 2 Thioredox_DsbH PF03190.10 AEO61160.1 - 5.1e-59 198.6 0.0 8.6e-59 197.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 AEO61160.1 - 0.00013 21.8 0.0 0.00043 20.2 0.0 2.0 1 0 0 1 1 1 1 Thioredoxin-like DUF4360 PF14273.1 AEO61162.1 - 3.3e-74 248.5 5.3 3.8e-74 248.3 3.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Citrate_synt PF00285.16 AEO61163.1 - 7.5e-102 340.6 0.0 8.9e-102 340.4 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase Gln-synt_C PF00120.19 AEO61164.1 - 2e-62 210.7 0.0 2.4e-62 210.4 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain VIGSSK PF14773.1 AEO61165.1 - 0.092 12.6 0.2 16 5.4 0.0 2.5 2 0 0 2 2 2 0 Helicase-associated putative binding domain, C-terminal AMP-binding PF00501.23 AEO61166.1 - 3.7e-68 229.8 0.1 1e-66 225.0 0.1 2.0 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 AEO61166.1 - 3e-11 44.1 0.0 9.6e-11 42.4 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Lipase_GDSL_2 PF13472.1 AEO61167.1 - 4.8e-18 65.9 4.6 5.7e-18 65.6 3.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 AEO61167.1 - 1.8e-10 41.0 0.6 2.2e-10 40.7 0.4 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Phage_lysozyme PF00959.14 AEO61167.1 - 0.15 12.3 0.3 1.1 9.5 0.1 2.3 2 0 0 2 2 2 0 Phage lysozyme HTH_29 PF13551.1 AEO61168.1 - 9.6e-10 38.6 1.6 1.2e-09 38.2 1.1 1.1 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 AEO61168.1 - 2.3e-06 28.2 1.8 4.6e-06 27.3 0.9 1.8 1 1 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.13 AEO61168.1 - 0.0075 16.3 3.3 0.01 15.8 0.4 2.1 2 0 0 2 2 2 1 Transposase EDR1 PF14381.1 AEO61168.1 - 0.011 15.3 0.0 0.054 13.0 0.0 1.8 2 0 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 DUF3210 PF11489.3 AEO61168.1 - 0.015 14.0 0.7 0.018 13.7 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3210) MarR_2 PF12802.2 AEO61168.1 - 0.016 14.8 0.2 0.049 13.2 0.0 1.9 2 0 0 2 2 2 0 MarR family RepB PF07506.6 AEO61168.1 - 0.017 15.0 0.3 0.021 14.6 0.2 1.1 1 0 0 1 1 1 0 RepB plasmid partitioning protein ATP-cone PF03477.11 AEO61168.1 - 0.045 14.1 0.0 0.089 13.2 0.0 1.5 1 0 0 1 1 1 0 ATP cone domain Sigma70_r4_2 PF08281.7 AEO61168.1 - 0.11 12.0 0.5 0.22 11.0 0.3 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_23 PF13384.1 AEO61168.1 - 2 8.1 6.5 3.5 7.3 0.0 2.9 3 0 0 3 3 3 0 Homeodomain-like domain PPDK_N PF01326.14 AEO61169.1 - 2.9e-90 302.6 0.5 7.2e-90 301.3 0.3 1.6 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers_C PF02896.13 AEO61169.1 - 5.8e-59 199.3 0.0 8.9e-59 198.7 0.0 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilizers PF00391.18 AEO61169.1 - 2.7e-24 84.5 0.4 2.7e-24 84.5 0.3 2.1 3 0 0 3 3 3 1 PEP-utilising enzyme, mobile domain Serglycin PF04360.7 AEO61169.1 - 1.9 8.1 7.4 7.6 6.2 1.1 2.5 2 0 0 2 2 2 0 Serglycin Ldh_1_N PF00056.18 AEO61170.1 - 2.7e-28 98.5 0.1 4.1e-28 97.9 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 AEO61170.1 - 3.4e-26 92.0 0.0 5.8e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain ThiF PF00899.16 AEO61170.1 - 0.0026 17.5 0.2 0.0054 16.5 0.1 1.5 1 0 0 1 1 1 1 ThiF family Malic_M PF03949.10 AEO61170.1 - 0.087 12.3 0.1 0.28 10.7 0.1 1.9 1 1 0 1 1 1 0 Malic enzyme, NAD binding domain UDPG_MGDP_dh_N PF03721.9 AEO61170.1 - 0.45 9.8 2.4 2.8 7.2 1.7 2.0 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain CDC45 PF02724.9 AEO61171.1 - 0.0069 14.4 18.6 0.0076 14.3 12.9 1.0 1 0 0 1 1 1 1 CDC45-like protein Paf1 PF03985.8 AEO61171.1 - 0.012 14.4 17.0 0.013 14.2 11.8 1.0 1 0 0 1 1 1 0 Paf1 Merozoite_SPAM PF07133.6 AEO61171.1 - 0.034 14.0 20.4 0.038 13.8 14.1 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Nop14 PF04147.7 AEO61171.1 - 0.037 11.9 18.6 0.035 12.0 12.9 1.0 1 0 0 1 1 1 0 Nop14-like family YqfQ PF14181.1 AEO61171.1 - 0.12 12.4 6.5 0.14 12.2 4.5 1.1 1 0 0 1 1 1 0 YqfQ-like protein SDA1 PF05285.7 AEO61171.1 - 0.15 11.3 17.7 0.15 11.3 12.3 1.1 1 0 0 1 1 1 0 SDA1 DUF3381 PF11861.3 AEO61171.1 - 0.32 10.5 13.4 0.39 10.2 9.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) MIP-T3 PF10243.4 AEO61171.1 - 0.45 8.9 17.7 0.49 8.7 12.3 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Med4 PF10018.4 AEO61171.1 - 0.49 9.7 10.6 0.65 9.3 7.4 1.1 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 TRAP_alpha PF03896.11 AEO61171.1 - 0.6 9.0 9.6 0.68 8.8 6.7 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF1510 PF07423.6 AEO61171.1 - 0.97 8.7 14.7 1 8.6 10.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Trypan_PARP PF05887.6 AEO61171.1 - 1.2 8.9 15.3 1.4 8.6 10.6 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) NPR3 PF03666.8 AEO61171.1 - 1.4 7.3 4.7 1.6 7.1 3.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Usp PF00582.21 AEO61171.1 - 1.6 8.8 4.5 2 8.6 3.1 1.2 1 0 0 1 1 1 0 Universal stress protein family Ycf1 PF05758.7 AEO61171.1 - 2.1 5.9 5.7 2 6.0 3.9 1.0 1 0 0 1 1 1 0 Ycf1 Vfa1 PF08432.5 AEO61171.1 - 2.2 8.2 9.1 2.6 8.0 6.3 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 TFIIF_alpha PF05793.7 AEO61171.1 - 2.8 6.2 22.2 2.8 6.1 15.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Spore_coat_CotO PF14153.1 AEO61171.1 - 3.8 6.9 10.5 4.3 6.7 7.3 1.1 1 0 0 1 1 1 0 Spore coat protein CotO DDHD PF02862.12 AEO61171.1 - 4 7.1 6.8 4.7 6.9 4.7 1.1 1 0 0 1 1 1 0 DDHD domain HSP90 PF00183.13 AEO61171.1 - 7.7 4.7 15.8 9.1 4.5 10.9 1.0 1 0 0 1 1 1 0 Hsp90 protein RNA_pol_Rpc4 PF05132.9 AEO61171.1 - 8.1 6.4 7.2 10 6.1 5.0 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Daxx PF03344.10 AEO61171.1 - 8.9 4.6 25.3 9.9 4.5 17.6 1.0 1 0 0 1 1 1 0 Daxx Family 2OG-FeII_Oxy PF03171.15 AEO61173.1 - 0.00017 21.8 0.0 0.00034 20.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 AEO61173.1 - 0.0015 19.0 0.1 0.0036 17.7 0.1 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Transferase PF02458.10 AEO61174.1 - 7.3e-09 34.5 0.0 1.5e-08 33.5 0.0 1.3 1 1 0 1 1 1 1 Transferase family Cation_ATPase_C PF00689.16 AEO61175.1 - 2.3 7.7 10.5 0.53 9.7 3.8 2.2 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus WD40 PF00400.27 AEO61176.1 - 1.3e-34 116.8 0.1 2.3e-05 24.0 0.0 8.3 8 0 0 8 8 8 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 AEO61176.1 - 0.098 12.1 0.0 10 5.7 0.0 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain GDC-P PF02347.11 AEO61177.1 - 3.3e-175 582.9 0.0 1.1e-161 538.2 0.0 2.9 3 1 0 3 3 3 2 Glycine cleavage system P-protein Aminotran_5 PF00266.14 AEO61177.1 - 9.7e-07 27.8 0.1 0.00029 19.7 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.16 AEO61177.1 - 1.1e-06 28.0 0.0 2.2e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 AEO61177.1 - 0.016 13.5 0.0 0.19 9.9 0.0 2.0 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme DnaG_DnaB_bind PF08278.6 AEO61177.1 - 0.071 13.3 0.1 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding Tom5 PF10642.4 AEO61178.1 - 9.4e-25 86.0 0.8 1e-24 85.9 0.6 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase Nup54 PF13874.1 AEO61179.1 - 3.7e-44 149.7 0.1 3.7e-44 149.7 0.0 2.2 3 0 0 3 3 3 1 Nucleoporin complex subunit 54 HOOK PF05622.7 AEO61179.1 - 0.0045 14.8 3.6 0.011 13.6 2.5 1.6 1 1 0 1 1 1 1 HOOK protein V-SNARE_C PF12352.3 AEO61179.1 - 0.023 14.7 0.2 9.4 6.3 0.0 2.5 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Nbl1_Borealin_N PF10444.4 AEO61179.1 - 0.082 12.2 0.3 0.26 10.6 0.1 1.9 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal DivIVA PF05103.8 AEO61179.1 - 1.5 8.8 7.9 0.18 11.8 1.0 2.4 2 1 0 2 2 2 0 DivIVA protein Seryl_tRNA_N PF02403.17 AEO61179.1 - 2 8.4 6.5 8.2 6.5 0.3 2.8 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CHCH PF06747.8 AEO61180.1 - 2.3e-09 36.8 15.9 2.4e-08 33.6 3.7 2.6 3 0 0 3 3 3 2 CHCH domain Cmc1 PF08583.5 AEO61180.1 - 3.7e-05 23.3 11.0 0.023 14.4 0.5 2.2 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like GCK PF07802.6 AEO61180.1 - 0.084 13.0 0.6 0.084 13.0 0.4 2.3 2 1 0 2 2 2 0 GCK domain Pet191_N PF10203.4 AEO61180.1 - 0.12 12.4 8.2 0.26 11.3 4.4 2.2 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 CAP PF00188.21 AEO61181.1 - 5e-17 62.5 3.2 7.1e-17 62.0 2.2 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Herpes_UL32 PF06070.6 AEO61181.1 - 0.0098 14.4 5.3 0.012 14.0 3.7 1.1 1 0 0 1 1 1 1 Herpesvirus large structural phosphoprotein UL32 Chorion_2 PF03964.10 AEO61181.1 - 0.064 13.7 3.7 0.5 10.9 2.6 2.3 1 1 0 1 1 1 0 Chorion family 2 MCPVI PF02993.9 AEO61181.1 - 5.4 7.0 14.4 7.9 6.5 10.0 1.1 1 0 0 1 1 1 0 Minor capsid protein VI DUF2082 PF09855.4 AEO61182.1 - 0.083 12.7 0.9 0.12 12.2 0.6 1.3 1 0 0 1 1 1 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) Ribosomal_S17 PF00366.15 AEO61182.1 - 0.26 11.3 1.3 0.31 11.0 0.4 1.5 1 1 1 2 2 2 0 Ribosomal protein S17 DUF3435 PF11917.3 AEO61183.1 - 0.031 13.0 0.0 0.033 12.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) Methyltransf_12 PF08242.7 AEO61184.1 - 2.8e-16 59.7 0.0 7.4e-16 58.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO61184.1 - 3.5e-10 39.6 0.0 7e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO61184.1 - 2.5e-09 37.5 0.0 4.2e-08 33.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO61184.1 - 5e-09 36.0 0.0 8.6e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO61184.1 - 1.4e-07 31.7 0.0 2.8e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 AEO61184.1 - 1.5e-07 30.7 0.0 3.1e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 AEO61184.1 - 1.5e-07 31.9 0.0 4.5e-07 30.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.20 AEO61184.1 - 4.4e-05 23.6 0.0 9.7e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_26 PF13659.1 AEO61184.1 - 0.00091 19.2 0.0 0.002 18.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 AEO61184.1 - 0.0092 14.9 0.0 1.5 7.6 0.0 2.1 2 0 0 2 2 2 2 NNMT/PNMT/TEMT family Methyltransf_PK PF05891.7 AEO61184.1 - 0.044 13.0 0.0 0.075 12.3 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Pox_MCEL PF03291.11 AEO61184.1 - 0.22 10.3 0.0 0.3 9.9 0.0 1.2 1 0 0 1 1 1 0 mRNA capping enzyme Cu-oxidase_3 PF07732.10 AEO61185.1 - 5.9e-39 132.4 5.9 5.8e-38 129.2 0.0 3.2 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 AEO61185.1 - 2.4e-28 98.3 5.8 8e-22 77.2 0.1 3.9 3 2 1 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.17 AEO61185.1 - 3.1e-15 56.4 0.0 1.1e-14 54.6 0.0 1.9 2 1 0 2 2 2 1 Multicopper oxidase DUF1295 PF06966.7 AEO61186.1 - 2.1e-12 46.8 0.0 2.9e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.11 AEO61186.1 - 8.4e-10 38.6 0.3 1.4e-09 37.8 0.0 1.5 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 AEO61186.1 - 1.3e-05 25.2 0.7 2.6e-05 24.2 0.0 1.9 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 AEO61186.1 - 5.9e-05 21.7 0.2 8.9e-05 21.2 0.1 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.9 AEO61186.1 - 6.3e-05 23.0 0.1 0.00025 21.2 0.0 1.9 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family NnrU PF07298.6 AEO61186.1 - 6.5e-05 22.3 0.2 9.4e-05 21.8 0.1 1.2 1 0 0 1 1 1 1 NnrU protein MFS_1 PF07690.11 AEO61187.1 - 3.1e-44 151.1 49.7 7.8e-44 149.8 32.4 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO61187.1 - 3.8e-16 58.7 21.0 3.3e-14 52.3 4.2 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter YbgT_YccB PF08173.6 AEO61187.1 - 0.029 14.2 3.2 0.095 12.5 0.4 3.0 2 0 0 2 2 2 0 Membrane bound YbgT-like protein OATP PF03137.15 AEO61187.1 - 0.38 8.7 6.8 1.2 7.1 1.5 2.5 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family FA_desaturase PF00487.19 AEO61187.1 - 1.3 8.3 13.6 0.41 10.0 4.3 2.9 2 1 0 2 2 2 0 Fatty acid desaturase EthD PF07110.6 AEO61188.1 - 8.1e-21 74.7 0.0 1.9e-19 70.3 0.0 2.1 1 1 0 1 1 1 1 EthD domain ketoacyl-synt PF00109.21 AEO61189.1 - 5.9e-79 265.1 0.0 1.5e-78 263.7 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 AEO61189.1 - 2.4e-43 148.6 0.0 2.2e-42 145.5 0.0 2.1 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 AEO61189.1 - 1.2e-32 112.2 0.5 3.4e-32 110.7 0.3 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 AEO61189.1 - 3.3e-23 83.1 0.0 2.4e-22 80.2 0.0 2.6 3 1 0 3 3 3 1 Thioesterase domain PP-binding PF00550.20 AEO61189.1 - 5.1e-16 58.6 10.9 1.3e-07 31.7 1.1 3.1 2 0 0 2 2 2 2 Phosphopantetheine attachment site Abhydrolase_5 PF12695.2 AEO61189.1 - 7.9e-08 32.1 0.8 0.0075 16.0 0.0 4.4 5 1 0 5 5 5 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 AEO61189.1 - 1.8e-06 27.1 0.0 4.3e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain DUF2974 PF11187.3 AEO61189.1 - 0.044 13.1 0.0 0.087 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Dicty_REP PF05086.7 AEO61189.1 - 0.28 8.8 0.0 0.46 8.1 0.0 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Glyco_hydro_18 PF00704.23 AEO61191.1 - 4.1e-09 36.3 0.0 7.1e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Peptidase_C58 PF03543.9 AEO61191.1 - 0.18 11.2 0.5 12 5.3 0.0 2.1 1 1 0 2 2 2 0 Yersinia/Haemophilus virulence surface antigen TfuA PF07812.7 AEO61193.1 - 0.0068 15.8 0.0 0.0099 15.3 0.0 1.2 1 0 0 1 1 1 1 TfuA-like protein CBM_19 PF03427.8 AEO61194.1 - 0.74 9.6 3.3 4.5 7.1 0.0 2.5 2 0 0 2 2 2 0 Carbohydrate binding domain (family 19) Peptidase_C2 PF00648.16 AEO61196.1 - 0.0012 17.9 0.0 0.077 11.9 0.0 2.9 3 0 0 3 3 3 1 Calpain family cysteine protease Zip PF02535.17 AEO61196.1 - 0.04 12.9 1.4 0.053 12.5 1.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.9 AEO61196.1 - 0.13 11.5 5.8 0.22 10.9 4.0 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Glyco_trans_2_3 PF13632.1 AEO61197.1 - 1e-45 155.8 8.6 1e-45 155.8 5.9 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 AEO61197.1 - 6.8e-07 29.3 0.0 1.7e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 AEO61197.1 - 3e-05 23.7 0.0 9.2e-05 22.1 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 AEO61197.1 - 0.0097 15.2 0.0 0.022 14.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_hydro_16 PF00722.16 AEO61198.1 - 1.1e-19 70.3 0.2 1.2e-18 67.0 0.1 2.2 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 Arabinose_trans PF04602.7 AEO61198.1 - 0.12 10.5 0.0 0.17 9.9 0.0 1.1 1 0 0 1 1 1 0 Mycobacterial cell wall arabinan synthesis protein Bacteriocin_IId PF09221.5 AEO61198.1 - 0.14 12.0 0.3 0.27 11.1 0.2 1.4 1 0 0 1 1 1 0 Bacteriocin class IId cyclical uberolysin-like Zn_clus PF00172.13 AEO61199.1 - 2.1e-06 27.5 5.3 3.3e-06 26.9 3.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Bacteriocin_IIc PF10439.4 AEO61200.1 - 6.9 6.8 8.4 0.47 10.6 1.7 2.0 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide APH PF01636.18 AEO61201.1 - 2e-15 57.1 4.7 3.5e-15 56.3 3.3 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 AEO61201.1 - 0.0057 16.2 0.0 0.0087 15.6 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 AEO61201.1 - 0.058 12.4 0.0 0.46 9.5 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pectinesterase PF01095.14 AEO61202.1 - 6.9e-51 172.5 7.3 9.3e-51 172.1 5.1 1.1 1 0 0 1 1 1 1 Pectinesterase Pec_lyase_C PF00544.14 AEO61203.1 - 6.4e-26 91.0 6.7 9.7e-26 90.4 4.7 1.3 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 AEO61203.1 - 2e-07 30.9 20.4 0.00034 20.4 9.4 2.6 1 1 1 2 2 2 2 Right handed beta helix region ABC_tran PF00005.22 AEO61205.1 - 6.5e-50 168.9 0.0 1.8e-27 96.2 0.0 4.1 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 AEO61205.1 - 2.6e-16 60.4 2.8 7.7e-07 29.3 0.1 3.5 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 AEO61205.1 - 2.5e-13 49.7 0.2 0.00041 19.6 0.0 4.3 4 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 AEO61205.1 - 2.9e-08 34.2 3.5 0.00011 22.6 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.1 AEO61205.1 - 8.4e-08 31.6 1.2 0.0044 16.5 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 AEO61205.1 - 3.9e-07 30.8 0.1 0.0061 17.3 0.0 3.2 3 0 0 3 3 2 2 AAA domain Chromo PF00385.19 AEO61205.1 - 7.5e-07 28.7 0.1 1.9e-06 27.4 0.1 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SbcCD_C PF13558.1 AEO61205.1 - 1.5e-06 28.0 0.0 0.053 13.4 0.0 3.5 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 AEO61205.1 - 1.5e-06 27.4 0.0 0.0083 15.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_15 PF13175.1 AEO61205.1 - 2.6e-06 26.7 0.0 0.36 9.8 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 AEO61205.1 - 3.3e-06 27.2 0.1 0.12 12.4 0.0 3.5 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.18 AEO61205.1 - 3.7e-06 26.8 0.0 0.012 15.5 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_10 PF12846.2 AEO61205.1 - 2.2e-05 24.0 2.8 0.26 10.6 0.1 4.0 4 2 0 4 4 4 2 AAA-like domain Miro PF08477.8 AEO61205.1 - 4.6e-05 23.8 0.0 0.091 13.2 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein AAA_33 PF13671.1 AEO61205.1 - 0.00016 21.5 0.0 0.22 11.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 AEO61205.1 - 0.00018 21.2 0.2 0.18 11.4 0.0 2.7 2 0 0 2 2 2 1 NACHT domain DUF87 PF01935.12 AEO61205.1 - 0.00021 21.1 0.7 0.096 12.4 0.0 3.4 3 0 0 3 3 3 1 Domain of unknown function DUF87 RNA_helicase PF00910.17 AEO61205.1 - 0.00036 20.6 0.1 1.2 9.3 0.0 2.6 2 0 0 2 2 2 2 RNA helicase ArgK PF03308.11 AEO61205.1 - 0.00047 19.0 0.2 0.15 10.7 0.0 2.4 2 0 0 2 2 2 1 ArgK protein MobB PF03205.9 AEO61205.1 - 0.00061 19.5 0.0 0.2 11.3 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 AEO61205.1 - 0.00091 19.5 0.1 0.084 13.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 AEO61205.1 - 0.0016 17.8 0.0 1.3 8.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 AEO61205.1 - 0.0017 18.3 0.0 0.053 13.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 AEO61205.1 - 0.0034 17.2 0.0 0.32 10.7 0.0 3.1 3 0 0 3 3 3 1 Dynamin family AAA_13 PF13166.1 AEO61205.1 - 0.0052 15.3 0.0 2 6.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 AEO61205.1 - 0.0057 16.8 0.0 3.1 7.9 0.0 2.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 AEO61205.1 - 0.0089 15.9 0.0 1.9 8.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 AEO61205.1 - 0.0097 15.9 1.1 1.5 8.8 0.1 3.5 3 0 0 3 3 3 1 AAA ATPase domain AAA_30 PF13604.1 AEO61205.1 - 0.012 15.2 0.3 7.9 5.9 0.0 3.4 4 0 0 4 4 2 0 AAA domain PduV-EutP PF10662.4 AEO61205.1 - 0.023 14.1 0.0 1.3 8.4 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation HEAT_2 PF13646.1 AEO61205.1 - 0.026 14.7 4.7 0.96 9.7 0.0 3.5 1 1 1 3 3 3 0 HEAT repeats FtsK_SpoIIIE PF01580.13 AEO61205.1 - 0.032 13.6 0.1 1.8 7.9 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family HEAT PF02985.17 AEO61205.1 - 0.036 14.1 0.6 42 4.5 0.0 4.9 4 0 0 4 4 4 0 HEAT repeat DUF815 PF05673.8 AEO61205.1 - 0.042 12.7 0.1 2.8 6.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NTPase_1 PF03266.10 AEO61205.1 - 0.051 13.2 0.4 9.8 5.8 0.1 2.9 2 0 0 2 2 2 0 NTPase Arch_ATPase PF01637.13 AEO61205.1 - 0.064 12.9 0.1 13 5.4 0.0 2.8 3 0 0 3 3 2 0 Archaeal ATPase Zeta_toxin PF06414.7 AEO61205.1 - 0.088 11.8 1.4 4.2 6.3 0.0 3.0 3 0 0 3 3 3 0 Zeta toxin DUF3584 PF12128.3 AEO61205.1 - 0.12 9.6 0.8 2.7 5.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) MutS_V PF00488.16 AEO61205.1 - 0.15 11.4 0.1 6.8 6.0 0.0 2.5 2 0 0 2 2 2 0 MutS domain V RRM_1 PF00076.17 AEO61207.1 - 5.8e-15 54.6 0.0 7.9e-15 54.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO61207.1 - 1.1e-13 50.9 0.0 1.6e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO61207.1 - 9.3e-08 31.8 0.0 1.4e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1777 PF08648.7 AEO61207.1 - 2.2 7.9 32.0 1.5 8.5 21.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1777) Pectate_lyase_3 PF12708.2 AEO61209.1 - 3.2e-68 230.2 10.7 2.1e-55 188.3 1.5 3.2 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 AEO61209.1 - 0.029 13.8 0.1 0.096 12.1 0.1 1.9 1 0 0 1 1 1 0 N terminal extension of bacteriophage endosialidase Rpp20 PF12328.3 AEO61211.1 - 5e-21 74.8 0.1 6.8e-21 74.4 0.1 1.2 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 AEO61211.1 - 1.4e-13 50.2 0.0 1.9e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Alba DUF1470 PF07336.6 AEO61211.1 - 0.0016 18.7 1.2 0.0028 17.9 0.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1470) PRC PF05239.11 AEO61211.1 - 0.027 14.3 0.0 0.037 13.8 0.0 1.2 1 0 0 1 1 1 0 PRC-barrel domain DUF4072 PF13284.1 AEO61211.1 - 1.6 8.9 4.6 0.36 11.0 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4072) Rogdi_lz PF10259.4 AEO61212.1 - 2.3e-82 276.2 0.0 2.6e-82 276.0 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein NIPSNAP PF07978.8 AEO61213.1 - 6.8e-36 122.3 0.3 2.5e-28 98.0 0.1 2.5 2 0 0 2 2 2 2 NIPSNAP SR-25 PF10500.4 AEO61213.1 - 0.21 11.0 6.3 0.34 10.3 4.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ATP-synt_J PF04911.7 AEO61214.1 - 7.5e-28 95.7 2.7 9.2e-28 95.4 1.8 1.1 1 0 0 1 1 1 1 ATP synthase j chain FSH1 PF03959.8 AEO61215.1 - 2.6e-54 183.8 0.0 3.4e-54 183.4 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 AEO61215.1 - 7.1e-06 26.0 0.0 0.028 14.3 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO61215.1 - 9.2e-05 22.2 0.0 0.00014 21.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 AEO61215.1 - 0.0024 17.2 0.0 0.56 9.4 0.1 2.4 1 1 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 AEO61215.1 - 0.0032 16.9 0.0 0.033 13.6 0.0 2.4 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase DUF4633 PF15464.1 AEO61215.1 - 0.062 13.1 0.1 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4633) Clr5 PF14420.1 AEO61217.1 - 1.7e-19 69.4 3.7 2.9e-19 68.6 2.6 1.4 1 0 0 1 1 1 1 Clr5 domain Sugar_tr PF00083.19 AEO61218.1 - 4e-76 256.4 23.6 4.8e-76 256.1 16.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO61218.1 - 1.6e-15 56.6 42.0 3.4e-13 49.0 9.3 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily YqjK PF13997.1 AEO61218.1 - 0.27 11.4 1.8 2.5 8.3 0.0 3.0 4 0 0 4 4 4 0 YqjK-like protein Amidoligase_2 PF12224.3 AEO61219.1 - 4.4e-19 69.0 0.0 1.7e-18 67.2 0.0 1.8 1 1 0 1 1 1 1 Putative amidoligase enzyme GSCFA PF08885.6 AEO61224.1 - 0.096 12.2 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 GSCFA family Glyco_hydro_71 PF03659.9 AEO61225.1 - 9.5e-138 458.8 0.7 1.2e-137 458.5 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Mucin PF01456.12 AEO61225.1 - 1.5 8.5 36.6 3 7.6 25.4 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein p450 PF00067.17 AEO61226.1 - 3.6e-50 170.8 0.0 7.2e-50 169.8 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Glyco_hydro_16 PF00722.16 AEO61227.1 - 1.5e-40 138.5 2.6 2.5e-40 137.7 1.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF605 PF04652.11 AEO61227.1 - 0.078 12.3 9.4 0.11 11.9 6.5 1.1 1 0 0 1 1 1 0 Vta1 like GRP PF07172.6 AEO61227.1 - 4.9 7.7 15.5 13 6.3 10.7 1.6 1 0 0 1 1 1 0 Glycine rich protein family zinc_ribbon_2 PF13240.1 AEO61228.1 - 0.031 13.7 1.6 0.031 13.7 1.1 2.4 2 1 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 AEO61228.1 - 3.5 6.9 11.3 1.7 7.9 3.8 3.0 2 2 0 2 2 2 0 zinc-ribbon domain YjeF_N PF03853.10 AEO61229.1 - 6e-37 126.8 0.0 7.4e-37 126.5 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Ribosomal_S16 PF00886.14 AEO61230.1 - 4.2e-25 87.2 0.1 6.1e-25 86.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S16 Aa_trans PF01490.13 AEO61231.1 - 3.7e-80 269.4 9.5 4.9e-80 269.0 6.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SH3_1 PF00018.23 AEO61233.1 - 1.4e-09 37.2 0.1 2.1e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 AEO61233.1 - 1.8e-07 30.5 0.0 3.1e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 AEO61233.1 - 8.3e-07 28.5 0.0 1.7e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain 7TMR-DISM_7TM PF07695.6 AEO61233.1 - 0.1 12.2 10.5 0.14 11.8 7.3 1.1 1 0 0 1 1 1 0 7TM diverse intracellular signalling DASH_Spc19 PF08287.6 AEO61234.1 - 5.1e-41 139.8 0.0 7.7e-41 139.2 0.0 1.2 1 0 0 1 1 1 1 Spc19 bZIP_1 PF00170.16 AEO61235.1 - 2.7e-09 36.8 10.1 4.7e-09 36.0 7.0 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 AEO61235.1 - 8.6e-09 35.0 11.0 8.6e-09 35.0 7.6 2.0 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 AEO61235.1 - 0.00057 20.1 7.1 0.0009 19.4 4.9 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor Shugoshin_N PF07558.6 AEO61235.1 - 0.0051 16.4 0.3 0.0098 15.5 0.2 1.4 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Takusan PF04822.8 AEO61235.1 - 0.046 13.4 3.9 0.088 12.5 2.7 1.4 1 0 0 1 1 1 0 Takusan Lzipper-MIP1 PF14389.1 AEO61235.1 - 0.047 13.7 1.7 0.096 12.8 0.5 1.9 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Atg14 PF10186.4 AEO61235.1 - 0.053 12.4 2.8 0.065 12.1 1.9 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4140 PF13600.1 AEO61235.1 - 0.065 13.6 3.4 0.12 12.7 2.3 1.5 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) IncA PF04156.9 AEO61235.1 - 0.43 10.1 6.2 0.63 9.6 4.3 1.2 1 0 0 1 1 1 0 IncA protein USP8_interact PF08941.5 AEO61235.1 - 0.5 9.6 2.8 0.78 9.0 1.9 1.3 1 0 0 1 1 1 0 USP8 interacting DUF2312 PF10073.4 AEO61235.1 - 0.69 9.2 5.5 0.99 8.8 3.8 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) DUF724 PF05266.9 AEO61235.1 - 2.4 7.7 8.1 3.2 7.3 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF1192 PF06698.6 AEO61235.1 - 3.1 7.6 7.9 9.3 6.1 1.8 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) ABC2_membrane PF01061.19 AEO61236.1 - 2.6e-91 304.4 50.5 2.6e-49 167.2 11.3 2.9 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.22 AEO61236.1 - 4.1e-37 127.5 0.1 6.2e-19 68.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 AEO61236.1 - 2.1e-32 110.8 0.5 2.2e-27 94.7 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 AEO61236.1 - 2.9e-06 26.5 28.2 3.5e-05 22.9 2.7 2.7 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.1 AEO61236.1 - 3.1e-06 27.1 0.0 1.4e-05 25.0 0.0 2.2 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal AAA_33 PF13671.1 AEO61236.1 - 6.5e-06 26.0 0.1 0.048 13.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain cobW PF02492.14 AEO61236.1 - 2.3e-05 23.9 0.0 0.014 14.8 0.1 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.1 AEO61236.1 - 3.4e-05 23.3 0.1 0.045 13.1 0.0 3.3 4 0 0 4 4 4 1 AAA domain DUF258 PF03193.11 AEO61236.1 - 0.00011 21.3 0.0 0.002 17.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 AEO61236.1 - 0.00026 21.1 0.0 0.53 10.4 0.0 3.3 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.1 AEO61236.1 - 0.00064 20.0 0.0 0.031 14.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 AEO61236.1 - 0.00085 19.2 0.3 0.15 12.0 0.2 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_21 PF13304.1 AEO61236.1 - 0.00091 19.2 0.3 1.2 9.0 0.0 2.8 2 1 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.13 AEO61236.1 - 0.001 18.6 0.1 1.2 8.5 0.0 2.6 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_29 PF13555.1 AEO61236.1 - 0.0012 18.3 0.2 0.32 10.5 0.1 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.1 AEO61236.1 - 0.0013 18.7 0.1 0.0043 17.0 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.1 AEO61236.1 - 0.0017 19.1 0.0 0.048 14.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 AEO61236.1 - 0.0043 17.0 2.9 0.019 14.9 0.2 3.0 3 0 0 3 3 2 1 AAA ATPase domain AAA_10 PF12846.2 AEO61236.1 - 0.011 15.1 0.3 4.2 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain NACHT PF05729.7 AEO61236.1 - 0.012 15.3 0.2 0.84 9.2 0.2 2.4 2 0 0 2 2 2 0 NACHT domain UPF0079 PF02367.12 AEO61236.1 - 0.04 13.5 2.8 0.35 10.5 0.2 2.6 3 0 0 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 SMC_N PF02463.14 AEO61236.1 - 0.049 12.8 0.0 0.45 9.7 0.0 2.4 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain Septin PF00735.13 AEO61236.1 - 0.06 12.3 0.0 0.46 9.4 0.0 2.0 2 0 0 2 2 2 0 Septin PduV-EutP PF10662.4 AEO61236.1 - 0.066 12.7 0.2 0.39 10.2 0.1 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 AEO61236.1 - 0.079 13.4 0.0 2.8 8.4 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein Arch_ATPase PF01637.13 AEO61236.1 - 0.11 12.1 0.1 5.8 6.5 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase RNA_helicase PF00910.17 AEO61236.1 - 0.18 11.9 0.0 19 5.4 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.1 AEO61236.1 - 0.25 10.8 0.2 1.2 8.6 0.1 2.0 2 0 0 2 2 2 0 AAA domain Cwf_Cwc_15 PF04889.7 AEO61236.1 - 0.4 10.3 0.0 0.4 10.3 0.0 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein NB-ARC PF00931.17 AEO61236.1 - 0.46 9.3 0.9 8.5 5.1 0.2 2.4 2 0 0 2 2 2 0 NB-ARC domain AMP-binding PF00501.23 AEO61237.1 - 0 1222.3 3.5 2.8e-87 292.8 0.0 6.9 5 2 1 6 6 6 5 AMP-binding enzyme Condensation PF00668.15 AEO61237.1 - 0 1211.3 0.0 1.9e-53 181.2 0.0 11.9 10 2 1 11 11 11 10 Condensation domain PP-binding PF00550.20 AEO61237.1 - 1.1e-77 256.2 1.2 1.6e-11 44.2 0.0 7.8 7 0 0 7 7 7 7 Phosphopantetheine attachment site AMP-binding_C PF13193.1 AEO61237.1 - 9.2e-22 77.7 3.8 0.0013 19.5 0.0 6.1 5 0 0 5 5 5 5 AMP-binding enzyme C-terminal domain Transferase PF02458.10 AEO61237.1 - 9.3e-05 21.0 0.0 3.2 6.0 0.0 3.6 3 0 0 3 3 3 3 Transferase family DUF3658 PF12395.3 AEO61237.1 - 0.38 10.3 0.6 13 5.4 0.0 3.7 5 0 0 5 5 5 0 Protein of unknown function ABC_tran PF00005.22 AEO61238.1 - 5.4e-47 159.5 0.0 3.2e-28 98.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 AEO61238.1 - 9.5e-35 120.3 28.9 1.5e-28 100.0 7.1 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 AEO61238.1 - 9.3e-11 41.3 1.8 7.2e-05 22.1 1.1 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 AEO61238.1 - 7.3e-08 32.7 0.8 0.011 15.7 0.0 3.8 3 1 1 4 4 3 1 AAA domain AAA_16 PF13191.1 AEO61238.1 - 5.2e-05 23.3 0.8 0.35 10.8 0.0 2.9 3 0 0 3 3 2 2 AAA ATPase domain T2SE PF00437.15 AEO61238.1 - 7.2e-05 21.8 0.0 0.25 10.1 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_25 PF13481.1 AEO61238.1 - 0.00013 21.4 0.0 0.043 13.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 AEO61238.1 - 0.00033 20.8 2.4 0.81 9.8 0.5 3.2 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 AEO61238.1 - 0.00044 19.7 0.4 0.37 10.3 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 AEO61238.1 - 0.00058 19.0 0.2 0.59 9.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 AEO61238.1 - 0.0015 19.0 2.0 0.13 12.8 0.1 2.5 2 0 0 2 2 2 1 Miro-like protein MobB PF03205.9 AEO61238.1 - 0.0019 17.8 0.4 2.6 7.7 0.1 2.9 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 AEO61238.1 - 0.005 17.1 0.5 3.8 7.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 AEO61238.1 - 0.006 16.5 0.1 3.8 7.4 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA PF00004.24 AEO61238.1 - 0.0065 16.6 1.1 3.7 7.7 0.0 3.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 AEO61238.1 - 0.0074 16.0 0.1 0.67 9.6 0.0 2.5 2 0 0 2 2 2 1 Archaeal ATPase AAA_10 PF12846.2 AEO61238.1 - 0.012 15.0 4.1 0.41 10.0 0.1 2.7 3 0 0 3 3 3 0 AAA-like domain AAA_33 PF13671.1 AEO61238.1 - 0.014 15.2 0.0 1.8 8.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 AEO61238.1 - 0.043 12.9 0.3 7.1 5.6 0.1 2.6 2 0 0 2 2 2 0 Zeta toxin AAA_14 PF13173.1 AEO61238.1 - 0.056 13.3 0.4 3 7.7 0.0 3.1 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.13 AEO61238.1 - 0.063 12.7 0.1 1.1 8.6 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family cobW PF02492.14 AEO61238.1 - 0.081 12.3 5.1 2.4 7.5 0.3 2.6 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain SbcCD_C PF13558.1 AEO61238.1 - 0.087 12.7 0.0 1.3 8.9 0.0 2.6 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.17 AEO61238.1 - 0.09 12.9 0.0 13 5.9 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Septin PF00735.13 AEO61238.1 - 0.17 10.9 0.3 9.8 5.0 0.0 2.2 2 0 0 2 2 2 0 Septin ATP-synt_ab PF00006.20 AEO61238.1 - 0.21 11.0 0.5 5.1 6.5 0.1 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.10 AEO61238.1 - 0.24 11.1 1.2 4.9 6.8 0.1 2.4 2 0 0 2 2 2 0 NTPase AAA_24 PF13479.1 AEO61238.1 - 0.24 10.9 1.2 4.1 6.9 0.1 2.5 2 1 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 AEO61238.1 - 0.25 10.8 0.9 5.2 6.5 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.17 AEO61238.1 - 0.25 10.1 0.8 30 3.3 0.0 3.0 3 0 0 3 3 3 0 NB-ARC domain AAA_17 PF13207.1 AEO61238.1 - 0.35 11.6 4.3 7.8 7.3 0.3 2.8 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 AEO61238.1 - 0.4 10.4 0.9 5.2 6.8 0.1 2.4 2 0 0 2 2 2 0 Dynamin family NACHT PF05729.7 AEO61238.1 - 0.41 10.3 4.0 4.8 6.8 0.1 2.9 3 0 0 3 3 3 0 NACHT domain DUF87 PF01935.12 AEO61238.1 - 0.48 10.2 1.0 0.74 9.5 0.0 1.7 2 0 0 2 2 1 0 Domain of unknown function DUF87 PduV-EutP PF10662.4 AEO61238.1 - 0.48 9.8 3.1 9 5.7 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF2075 PF09848.4 AEO61238.1 - 0.61 8.9 0.0 6.4 5.6 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 AEO61238.1 - 1.2 9.5 2.7 12 6.2 0.2 2.6 2 0 0 2 2 2 0 AAA domain DUF1583 PF07622.6 AEO61239.1 - 0.031 12.7 0.3 0.17 10.3 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1583) DAO PF01266.19 AEO61240.1 - 0.011 14.6 0.1 0.024 13.5 0.0 1.6 2 1 1 3 3 3 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 AEO61241.1 - 0.00015 20.9 0.1 0.00017 20.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Chitin_bind_1 PF00187.14 AEO61242.1 - 8.8e-17 60.8 73.1 2.6e-06 27.3 9.5 4.4 3 2 0 3 3 3 3 Chitin recognition protein DUF2360 PF10152.4 AEO61242.1 - 0.1 12.8 0.8 2.2 8.5 0.1 2.1 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Mucin PF01456.12 AEO61242.1 - 0.29 10.9 31.7 0.19 11.4 7.1 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein MIP PF00230.15 AEO61243.1 - 1.6e-41 142.2 17.3 2.4e-32 112.2 9.1 2.1 2 0 0 2 2 2 2 Major intrinsic protein DUF165 PF02592.10 AEO61243.1 - 5.9 7.0 11.0 0.38 10.9 0.1 3.2 1 1 2 3 3 3 0 Uncharacterized ACR, YhhQ family COG1738 adh_short PF00106.20 AEO61244.1 - 1.7e-17 63.8 0.1 2.8e-17 63.1 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO61244.1 - 1.4e-06 28.1 0.5 2.3e-06 27.4 0.3 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 AEO61244.1 - 1.8e-06 28.0 0.0 2.9e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 AEO61244.1 - 3.7e-06 26.5 0.0 4.6e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 AEO61244.1 - 0.0087 15.8 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Cofilin_ADF PF00241.15 AEO61245.1 - 3.5e-17 62.4 0.0 3.9e-17 62.3 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein CopB PF05275.6 AEO61245.1 - 0.065 12.4 0.1 1.7 7.8 0.0 2.0 1 1 1 2 2 2 0 Copper resistance protein B precursor (CopB) Glyco_hydro_3 PF00933.16 AEO61246.1 - 4.6e-94 314.7 0.0 6.2e-94 314.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 AEO61246.1 - 7e-55 186.0 0.2 1.3e-53 181.8 0.0 2.8 2 1 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 AEO61246.1 - 2.3e-21 75.4 0.2 5.6e-21 74.2 0.1 1.7 2 0 0 2 2 2 1 Fibronectin type III-like domain GSHPx PF00255.14 AEO61246.1 - 0.19 11.0 0.0 0.42 10.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione peroxidase SSF PF00474.12 AEO61247.1 - 7e-17 61.1 31.5 7e-17 61.1 21.8 1.5 1 1 0 1 1 1 1 Sodium:solute symporter family AIG2 PF06094.7 AEO61249.1 - 1.4e-08 35.0 0.1 2.4e-08 34.3 0.1 1.3 1 0 0 1 1 1 1 AIG2-like family Guanylate_kin PF00625.16 AEO61250.1 - 2e-33 115.3 0.0 2.4e-32 111.8 0.0 1.9 1 1 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.1 AEO61250.1 - 8.2e-07 29.3 0.0 1.4e-06 28.6 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AEO61250.1 - 7.2e-06 25.9 0.0 1.4e-05 25.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AEO61250.1 - 1.8e-05 25.5 0.0 2.5e-05 25.0 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 AEO61250.1 - 4.2e-05 23.7 0.0 0.00015 21.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 AEO61250.1 - 0.0011 18.8 0.0 0.0014 18.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 AEO61250.1 - 0.0011 18.1 0.0 0.0014 17.7 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_28 PF13521.1 AEO61250.1 - 0.0093 15.9 0.0 0.018 15.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 AEO61250.1 - 0.017 14.8 0.0 0.02 14.6 0.0 1.1 1 0 0 1 1 1 0 Archaeal ATPase RNA_helicase PF00910.17 AEO61250.1 - 0.028 14.5 0.0 0.039 14.1 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.1 AEO61250.1 - 0.032 14.2 0.0 0.039 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain KaiC PF06745.8 AEO61250.1 - 0.039 13.0 0.0 0.052 12.6 0.0 1.2 1 0 0 1 1 1 0 KaiC NB-ARC PF00931.17 AEO61250.1 - 0.05 12.4 0.0 0.061 12.1 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain NTPase_1 PF03266.10 AEO61250.1 - 0.05 13.3 0.0 0.092 12.4 0.0 1.5 1 0 0 1 1 1 0 NTPase NACHT PF05729.7 AEO61250.1 - 0.053 13.1 0.0 0.08 12.5 0.0 1.3 1 0 0 1 1 1 0 NACHT domain MobB PF03205.9 AEO61250.1 - 0.076 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 AEO61250.1 - 0.083 12.8 0.0 0.11 12.3 0.0 1.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA PF00004.24 AEO61250.1 - 0.1 12.7 0.0 0.15 12.2 0.0 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Formyl_trans_N PF00551.14 AEO61251.1 - 9e-36 123.1 0.1 1.1e-35 122.7 0.1 1.1 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.20 AEO61251.1 - 5.5e-09 35.3 0.0 2.6e-08 33.1 0.0 2.1 2 0 0 2 2 2 1 ACT domain ACT_6 PF13740.1 AEO61251.1 - 0.001 18.7 0.0 0.0031 17.2 0.0 1.9 1 0 0 1 1 1 1 ACT domain TroA PF01297.12 AEO61251.1 - 0.021 14.0 0.0 0.03 13.5 0.0 1.2 1 0 0 1 1 1 0 Periplasmic solute binding protein family MFS_1 PF07690.11 AEO61252.1 - 5.6e-36 123.9 5.7 5.6e-36 123.9 4.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO61252.1 - 4e-11 42.1 5.9 4e-11 42.1 4.1 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 AEO61252.1 - 0.0002 19.8 3.6 0.0002 19.8 2.5 3.6 2 2 2 4 4 4 2 MFS/sugar transport protein MFS_3 PF05977.8 AEO61252.1 - 0.00035 18.8 3.2 0.00035 18.8 2.2 2.1 2 0 0 2 2 2 1 Transmembrane secretion effector TRI12 PF06609.8 AEO61252.1 - 0.00048 18.4 2.2 0.00072 17.8 1.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) LacY_symp PF01306.14 AEO61252.1 - 0.023 13.2 0.4 0.045 12.3 0.2 1.4 1 0 0 1 1 1 0 LacY proton/sugar symporter TPR_11 PF13414.1 AEO61253.1 - 4.9e-13 48.5 10.9 1.1e-06 28.1 1.2 5.3 4 2 1 5 5 5 3 TPR repeat TPR_2 PF07719.12 AEO61253.1 - 8.9e-09 34.6 26.3 0.00065 19.4 0.1 7.4 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_12 PF13424.1 AEO61253.1 - 7.2e-08 32.2 15.9 0.0026 17.6 0.2 5.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.1 AEO61253.1 - 4.5e-07 29.1 4.7 0.32 10.8 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 AEO61253.1 - 8.8e-07 28.2 11.3 0.015 14.9 0.1 6.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 AEO61253.1 - 5.3e-06 26.9 31.6 0.023 15.3 2.4 7.4 6 2 1 7 7 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 AEO61253.1 - 5.2e-05 23.5 26.6 0.75 10.6 0.1 8.4 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 AEO61253.1 - 0.00018 21.0 1.7 2.3 8.1 0.1 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 AEO61253.1 - 0.001 19.1 1.2 9.3 6.7 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 AEO61253.1 - 0.0017 18.6 15.9 0.18 12.1 0.1 6.5 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_4 PF07721.9 AEO61253.1 - 3.5 8.3 36.4 0.12 12.9 1.1 7.0 7 0 0 7 7 6 0 Tetratricopeptide repeat Phospholip_A2_3 PF09056.6 AEO61254.1 - 1.3e-38 131.5 2.7 5.4e-38 129.6 1.9 1.9 1 1 0 1 1 1 1 Prokaryotic phospholipase A2 Phycoerythr_ab PF02972.9 AEO61254.1 - 0.12 11.9 0.3 6.1 6.5 0.0 2.3 2 0 0 2 2 2 0 Phycoerythrin, alpha/beta chain Esterase PF00756.15 AEO61255.1 - 0.013 14.9 0.0 0.032 13.6 0.0 1.5 1 1 1 2 2 2 0 Putative esterase Pkinase PF00069.20 AEO61256.1 - 2.2e-62 210.5 0.0 3.8e-62 209.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO61256.1 - 1.1e-35 122.9 0.0 2.3e-35 121.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 AEO61256.1 - 7.5e-26 89.6 25.1 1.1e-15 57.1 3.5 2.7 3 0 0 3 3 3 2 Hr1 repeat C1_1 PF00130.17 AEO61256.1 - 1.3e-20 72.8 26.2 3.8e-12 45.7 6.5 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 AEO61256.1 - 1.5e-14 54.1 2.0 6.1e-14 52.2 1.4 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 AEO61256.1 - 0.022 13.7 0.0 0.042 12.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like MAP65_ASE1 PF03999.7 AEO61256.1 - 3.2 6.2 8.9 6.9 5.1 6.1 1.4 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Glyco_hydro_61 PF03443.9 AEO61257.1 - 2.9e-73 246.2 0.2 3.4e-73 246.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 RdRP PF05183.7 AEO61258.1 - 2.3e-136 455.8 0.0 4.4e-134 448.3 0.0 2.2 1 1 0 1 1 1 1 RNA dependent RNA polymerase Meth_synt_2 PF01717.13 AEO61259.1 - 4.3e-10 39.0 0.0 4.2e-09 35.8 0.0 2.3 2 1 0 2 2 2 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 AEO61259.1 - 0.00036 19.9 0.1 0.0029 16.9 0.0 2.3 3 1 1 4 4 4 1 Cobalamin-independent synthase, N-terminal domain Abhydrolase_6 PF12697.2 AEO61260.1 - 4.6e-28 98.6 2.6 8.3e-28 97.8 0.4 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO61260.1 - 1e-09 38.3 0.0 2.1e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 AEO61260.1 - 7.1e-07 29.0 0.0 1.6e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family EthD PF07110.6 AEO61260.1 - 9.1e-05 23.3 0.5 0.074 13.9 0.1 3.1 2 1 0 3 3 3 2 EthD domain Ndr PF03096.9 AEO61260.1 - 0.0012 17.3 0.0 0.0025 16.3 0.0 1.5 1 0 0 1 1 1 1 Ndr family Esterase PF00756.15 AEO61260.1 - 0.017 14.5 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Chitin_bind_3 PF03067.10 AEO61261.1 - 7.7e-06 26.2 0.1 1.2e-05 25.6 0.1 1.3 1 0 0 1 1 1 1 Chitin binding domain Glyco_hydro_7 PF00840.15 AEO61262.1 - 1.4e-190 633.2 12.9 1.7e-190 633.0 8.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 DUF3764 PF12594.3 AEO61262.1 - 0.015 15.0 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3764) GMC_oxred_N PF00732.14 AEO61263.1 - 6.4e-34 117.4 0.0 8e-31 107.2 0.0 2.8 1 1 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 AEO61263.1 - 4.4e-29 101.6 0.0 7.4e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 AEO61263.1 - 0.00078 19.4 0.0 0.0027 17.6 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 AEO61263.1 - 0.001 18.0 0.0 0.073 11.9 0.0 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 AEO61263.1 - 0.0012 18.7 0.0 0.014 15.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 AEO61263.1 - 0.0039 16.2 0.0 0.0058 15.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 AEO61263.1 - 0.013 14.4 0.1 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 AEO61263.1 - 0.014 14.2 0.1 0.039 12.8 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.1 AEO61263.1 - 0.021 14.8 0.0 1.9 8.5 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 AEO61263.1 - 0.34 9.3 0.0 0.54 8.6 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein MFS_1 PF07690.11 AEO61264.1 - 7.2e-39 133.4 45.2 7.2e-39 133.4 31.3 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 AEO61264.1 - 4.6e-17 61.4 18.9 6.4e-17 60.9 13.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2985 PF11204.3 AEO61265.1 - 8.4e-24 83.1 4.8 1.6e-23 82.2 3.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) YhhN PF07947.9 AEO61266.1 - 2.3e-34 118.3 17.0 2.3e-34 118.3 11.8 1.4 1 1 0 1 1 1 1 YhhN-like protein AA_permease_2 PF13520.1 AEO61267.1 - 2.5e-45 154.7 51.6 3.3e-45 154.4 35.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 AEO61267.1 - 1.7e-24 86.0 48.4 2.3e-24 85.5 33.6 1.0 1 0 0 1 1 1 1 Amino acid permease HD PF01966.17 AEO61268.1 - 4.5e-05 23.4 0.0 6.5e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 HD domain F-box-like PF12937.2 AEO61272.1 - 1.8e-07 30.7 0.3 2.6e-07 30.2 0.2 1.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 AEO61272.1 - 8.9e-06 25.2 0.2 1.3e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 F-box domain zf-CCHC PF00098.18 AEO61274.1 - 0.00011 21.9 1.4 0.00016 21.4 1.0 1.2 1 0 0 1 1 1 1 Zinc knuckle Histone PF00125.19 AEO61275.1 - 2.2e-22 78.9 0.1 2.8e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 AEO61275.1 - 4.9e-05 23.3 0.0 6.8e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone zf-dskA_traR PF01258.12 AEO61276.1 - 0.062 13.0 0.1 0.14 11.9 0.1 1.6 1 0 0 1 1 1 0 Prokaryotic dksA/traR C4-type zinc finger SnoaL_4 PF13577.1 AEO61278.1 - 1.1e-15 57.6 0.4 1.8e-15 56.9 0.3 1.3 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 AEO61278.1 - 0.00037 20.6 1.2 0.00055 20.1 0.9 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) PA-IL PF07828.7 AEO61278.1 - 0.065 13.0 0.0 0.088 12.6 0.0 1.2 1 0 0 1 1 1 0 PA-IL-like protein Transferase PF02458.10 AEO61279.1 - 2.1e-19 69.3 0.0 2.3e-18 65.8 0.0 1.9 1 1 0 1 1 1 1 Transferase family ketoacyl-synt PF00109.21 AEO61282.1 - 4.2e-63 213.1 0.2 8.4e-63 212.2 0.2 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 AEO61282.1 - 9.5e-58 194.8 1.3 9.5e-58 194.8 0.9 2.6 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.16 AEO61282.1 - 9.1e-54 182.9 0.2 2.8e-53 181.3 0.1 1.9 2 0 0 2 2 2 1 Acyl transferase domain adh_short PF00106.20 AEO61282.1 - 1.7e-46 158.2 12.0 1.1e-45 155.5 0.9 3.6 3 0 0 3 3 3 2 short chain dehydrogenase PS-DH PF14765.1 AEO61282.1 - 1.4e-36 126.2 5.4 1.4e-36 126.2 3.7 2.0 2 0 0 2 2 2 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 AEO61282.1 - 7.3e-34 116.1 4.0 2.5e-33 114.4 0.0 3.8 4 0 0 4 4 4 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 AEO61282.1 - 9.2e-18 64.5 0.0 2.9e-17 62.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 AEO61282.1 - 6.1e-14 51.6 3.5 4.8e-13 48.7 0.5 3.2 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 AEO61282.1 - 7.8e-14 51.7 0.0 2.8e-13 49.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO61282.1 - 5.6e-11 42.2 0.0 1.2e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO61282.1 - 1.7e-10 41.4 0.4 6.7e-09 36.3 0.0 3.5 4 0 0 4 4 3 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO61282.1 - 2.2e-09 37.7 0.0 1.6e-08 34.9 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.20 AEO61282.1 - 3.6e-09 36.7 0.0 4.7e-08 33.1 0.0 2.6 2 0 0 2 2 2 1 Phosphopantetheine attachment site ADH_zinc_N_2 PF13602.1 AEO61282.1 - 2.3e-08 35.0 0.1 3.2e-07 31.3 0.0 3.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_26 PF13659.1 AEO61282.1 - 3.5e-05 23.8 1.3 0.00023 21.1 0.1 3.1 2 0 0 2 2 2 1 Methyltransferase domain Saccharop_dh PF03435.13 AEO61282.1 - 0.00018 20.5 0.0 0.00034 19.7 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Ubie_methyltran PF01209.13 AEO61282.1 - 0.00091 18.3 0.0 0.0017 17.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family ACP_syn_III PF08545.5 AEO61282.1 - 0.0036 16.9 0.4 0.011 15.3 0.3 1.9 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 AEO61282.1 - 0.0044 16.0 0.1 0.011 14.7 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_28 PF02636.12 AEO61282.1 - 0.0069 15.8 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Shikimate_DH PF01488.15 AEO61282.1 - 0.026 14.6 0.0 0.14 12.3 0.0 2.2 2 0 0 2 2 1 0 Shikimate / quinate 5-dehydrogenase adh_short_C2 PF13561.1 AEO61282.1 - 0.045 13.5 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 AEO61282.1 - 0.084 12.2 0.0 0.56 9.5 0.0 2.3 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Methyltransf_16 PF10294.4 AEO61282.1 - 0.086 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Polysacc_synt_2 PF02719.10 AEO61282.1 - 0.098 11.5 0.0 0.2 10.5 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NmrA PF05368.8 AEO61282.1 - 0.12 11.6 0.0 0.23 10.6 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family 3Beta_HSD PF01073.14 AEO61282.1 - 0.66 8.6 0.0 1.1 7.8 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family R3H PF01424.17 AEO61283.1 - 1.3e-10 40.8 0.0 3e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 R3H domain RRM_6 PF14259.1 AEO61283.1 - 6.2e-08 32.5 0.0 1.1e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 AEO61283.1 - 1.6e-07 30.8 0.0 2.8e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO61283.1 - 1.4e-05 24.8 0.4 3.7e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_2 PF04059.7 AEO61283.1 - 0.026 14.5 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif 2 Inositol_P PF00459.20 AEO61284.1 - 9.8e-36 123.4 0.1 1.9e-35 122.4 0.0 1.4 1 1 0 1 1 1 1 Inositol monophosphatase family DUF1996 PF09362.5 AEO61285.1 - 8e-78 261.3 0.5 9.9e-78 261.0 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Na_Ca_ex PF01699.19 AEO61286.1 - 9.3e-36 122.5 29.5 3.9e-21 75.1 5.0 3.4 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF307 PF03733.8 AEO61286.1 - 2.3e-14 53.5 15.2 2.3e-14 53.5 10.5 3.8 3 0 0 3 3 3 1 Domain of unknown function (DUF307) Nucleoplasmin PF03066.10 AEO61286.1 - 0.26 10.8 5.4 0.61 9.6 3.7 1.6 1 0 0 1 1 1 0 Nucleoplasmin DUF2457 PF10446.4 AEO61286.1 - 0.26 9.9 9.2 0.44 9.2 6.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RXT2_N PF08595.6 AEO61286.1 - 4.8 6.9 5.0 8.5 6.1 3.5 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal CDC45 PF02724.9 AEO61286.1 - 4.9 5.0 4.2 7.2 4.5 2.9 1.1 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.1 AEO61286.1 - 8.6 6.7 11.0 3.8 7.8 5.5 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AAA PF00004.24 AEO61287.1 - 5.1e-44 149.6 0.0 8.5e-44 148.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 AEO61287.1 - 3.1e-08 33.4 0.0 7.5e-08 32.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 AEO61287.1 - 1.2e-07 31.8 0.0 2.2e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 AEO61287.1 - 3.2e-06 27.2 0.0 1e-05 25.6 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 AEO61287.1 - 4.5e-06 26.8 0.1 0.00025 21.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AEO61287.1 - 6.1e-05 23.8 0.0 0.00015 22.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 AEO61287.1 - 7.6e-05 21.8 0.0 0.00013 21.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 AEO61287.1 - 0.00014 21.5 0.1 0.00029 20.5 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 AEO61287.1 - 0.00042 19.7 0.0 0.00076 18.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 AEO61287.1 - 0.00089 18.0 0.0 0.0016 17.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 AEO61287.1 - 0.0014 18.5 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 AEO61287.1 - 0.0017 18.2 0.0 0.0029 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 AEO61287.1 - 0.0022 17.5 0.0 0.0074 15.8 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 AEO61287.1 - 0.0023 17.0 0.0 0.0044 16.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 AEO61287.1 - 0.0037 17.2 0.0 0.0067 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AEO61287.1 - 0.0065 16.7 0.0 0.028 14.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 AEO61287.1 - 0.0069 15.5 0.0 0.015 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI KaiC PF06745.8 AEO61287.1 - 0.0075 15.4 0.0 0.017 14.2 0.0 1.5 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.1 AEO61287.1 - 0.017 14.5 0.1 0.081 12.3 0.0 1.9 1 1 1 2 2 2 0 AAA domain DUF815 PF05673.8 AEO61287.1 - 0.018 13.9 0.0 0.033 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.21 AEO61287.1 - 0.019 14.4 0.0 0.085 12.3 0.0 2.0 3 0 0 3 3 2 0 Sigma-54 interaction domain PhoH PF02562.11 AEO61287.1 - 0.019 14.2 0.0 0.07 12.3 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.1 AEO61287.1 - 0.021 14.4 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 AEO61287.1 - 0.028 14.5 0.0 0.053 13.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DUF2072 PF09845.4 AEO61287.1 - 0.042 13.7 0.1 0.092 12.6 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Sigma54_activ_2 PF14532.1 AEO61287.1 - 0.046 13.7 0.0 0.12 12.4 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain Histone PF00125.19 AEO61287.1 - 0.046 13.8 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Parvo_NS1 PF01057.12 AEO61287.1 - 0.051 12.4 0.0 0.086 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 AEO61287.1 - 0.076 11.8 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.7 AEO61287.1 - 0.099 12.2 0.0 0.53 9.9 0.0 2.0 1 1 1 2 2 2 0 NACHT domain Y_phosphatase PF00102.22 AEO61288.1 - 1e-12 47.9 0.0 1.7e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 AEO61288.1 - 1.7e-11 44.4 0.0 3.5e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain BC10 PF06726.7 AEO61289.1 - 1e-16 60.6 12.0 1.8e-16 59.9 8.3 1.4 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 DUF2838 PF10998.3 AEO61289.1 - 0.35 10.7 4.9 0.52 10.2 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2838) Harakiri PF15196.1 AEO61291.1 - 0.062 13.5 0.3 0.075 13.2 0.2 1.2 1 0 0 1 1 1 0 Activator of apoptosis harakiri Zn_clus PF00172.13 AEO61292.1 - 1.1e-08 34.8 12.7 2.3e-08 33.7 8.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 AEO61292.1 - 0.062 12.1 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Ribosomal_S19 PF00203.16 AEO61293.1 - 3.2e-23 81.1 0.1 5e-23 80.5 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein S19 TFIID_30kDa PF03540.8 AEO61294.1 - 1.9e-26 91.6 0.4 3.9e-26 90.6 0.2 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Mre11_DNA_bind PF04152.9 AEO61295.1 - 3.9e-59 199.4 1.5 3.9e-59 199.4 1.0 1.9 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 AEO61295.1 - 1e-25 90.3 1.7 1.4e-25 89.8 1.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 AEO61295.1 - 7.7e-06 25.8 0.1 1.9e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain APC10 PF03256.11 AEO61296.1 - 5.4e-46 156.6 0.0 7.3e-46 156.2 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.20 AEO61296.1 - 0.0067 16.2 0.0 0.012 15.4 0.0 1.5 2 0 0 2 2 2 1 F5/8 type C domain PITH PF06201.8 AEO61296.1 - 0.15 11.8 0.0 2.3 7.9 0.0 2.0 2 0 0 2 2 2 0 PITH domain CTP_transf_2 PF01467.21 AEO61297.1 - 0.028 14.4 0.1 0.085 12.8 0.0 1.9 2 1 0 2 2 2 0 Cytidylyltransferase DPBB_1 PF03330.13 AEO61297.1 - 0.045 13.7 0.0 0.078 12.9 0.0 1.4 1 0 0 1 1 1 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel CEP170_C PF15308.1 AEO61297.1 - 0.2 9.8 0.0 0.28 9.3 0.0 1.1 1 0 0 1 1 1 0 CEP170 C-terminus PTR2 PF00854.16 AEO61298.1 - 2.2e-26 92.5 0.0 1.3e-12 47.2 0.0 2.2 1 1 1 2 2 2 2 POT family Asp PF00026.18 AEO61299.1 - 6.6e-43 147.1 0.5 2.1e-38 132.3 0.3 3.2 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.1 AEO61299.1 - 0.0028 17.6 0.3 0.012 15.6 0.2 2.0 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Striatin PF08232.7 AEO61300.1 - 2.7e-36 124.8 2.8 2.7e-36 124.8 1.9 2.9 3 0 0 3 3 3 1 Striatin family WD40 PF00400.27 AEO61300.1 - 8.1e-32 107.9 11.6 3.4e-06 26.7 0.0 6.9 6 0 0 6 6 6 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 AEO61300.1 - 0.071 11.3 0.0 0.18 10.0 0.0 1.6 2 0 0 2 2 2 0 Cytochrome D1 heme domain DUF4175 PF13779.1 AEO61300.1 - 0.41 8.2 46.2 0.0083 13.8 27.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) EIIBC-GUT_N PF03612.9 AEO61300.1 - 6.7 6.2 9.2 15 5.1 6.4 1.5 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Hid1 PF12722.2 AEO61300.1 - 6.8 4.2 15.5 9.6 3.7 10.7 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF775 PF05603.7 AEO61300.1 - 7.3 6.0 14.7 14 5.1 10.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF775) XPA_C PF05181.7 AEO61301.1 - 4.6e-29 99.7 6.6 4.8e-29 99.6 3.0 2.2 2 0 0 2 2 2 1 XPA protein C-terminus XPA_N PF01286.13 AEO61301.1 - 0.00072 19.1 5.0 0.0015 18.1 3.4 1.6 1 0 0 1 1 1 1 XPA protein N-terminal zf-C3HC4_3 PF13920.1 AEO61301.1 - 0.18 11.5 7.6 0.52 10.0 3.1 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Pho88 PF10032.4 AEO61302.1 - 1.5e-78 262.4 0.0 1.6e-78 262.3 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) GMC_oxred_N PF00732.14 AEO61303.1 - 2.4e-29 102.4 0.0 4e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 AEO61303.1 - 1.1e-11 44.2 0.1 1.9e-05 23.7 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 AEO61303.1 - 9.2e-11 41.2 0.1 9.3e-05 21.4 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 AEO61303.1 - 4.5e-06 26.7 0.0 2.7e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AEO61303.1 - 4.5e-05 23.3 0.0 0.00011 22.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 AEO61303.1 - 6.4e-05 23.0 0.1 0.053 13.5 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 AEO61303.1 - 0.00086 17.8 0.0 0.0063 15.0 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 AEO61303.1 - 0.0019 17.3 0.4 0.0048 16.0 0.1 1.7 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 AEO61303.1 - 0.0027 18.0 0.0 0.74 10.2 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 AEO61303.1 - 0.0075 15.3 0.0 0.7 8.9 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase GMC_oxred_C PF05199.8 AEO61303.1 - 0.067 13.4 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 GMC oxidoreductase Lycopene_cycl PF05834.7 AEO61303.1 - 0.083 11.7 0.1 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 AEO61303.1 - 0.11 11.4 0.2 0.22 10.5 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain Glyco_hydro_61 PF03443.9 AEO61304.1 - 1.8e-55 188.1 0.3 2.1e-55 187.9 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_61 PF03443.9 AEO61305.1 - 6.1e-51 173.3 0.5 7.2e-51 173.0 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF3931 PF13082.1 AEO61305.1 - 0.13 12.1 0.0 8.4 6.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3931) CEP170_C PF15308.1 AEO61306.1 - 0.089 11.0 5.2 0.11 10.7 3.6 1.0 1 0 0 1 1 1 0 CEP170 C-terminus Clr5 PF14420.1 AEO61307.1 - 2.5e-15 56.0 4.7 2.6e-15 56.0 2.3 1.8 2 0 0 2 2 2 1 Clr5 domain TPR_12 PF13424.1 AEO61307.1 - 3.9e-12 45.9 0.1 5.3e-05 23.0 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 AEO61307.1 - 0.0022 17.8 0.2 1.5 8.8 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 AEO61307.1 - 0.0033 17.9 0.1 5.2 7.9 0.0 3.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.9 AEO61307.1 - 0.024 15.0 0.7 1.4 9.5 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 AEO61307.1 - 0.098 12.6 0.1 2.1 8.4 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 AEO61307.1 - 0.13 11.9 0.0 20 4.9 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Peptidase_M50 PF02163.17 AEO61308.1 - 0.035 13.0 0.6 0.052 12.4 0.3 1.5 1 1 0 1 1 1 0 Peptidase family M50 DUF4134 PF13572.1 AEO61308.1 - 0.14 12.3 1.2 0.22 11.6 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4134) HET PF06985.6 AEO61309.1 - 5.7e-18 65.4 0.0 1e-17 64.6 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Amidohydro_1 PF01979.15 AEO61310.1 - 1.1e-36 127.1 0.0 1.4e-36 126.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 AEO61310.1 - 3.2e-12 46.3 0.5 7.2e-09 35.3 0.0 2.9 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 AEO61310.1 - 3.1e-09 37.2 1.4 1e-07 32.2 1.0 2.3 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 AEO61310.1 - 3.1e-05 23.6 0.0 7.1e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase A_deaminase PF00962.17 AEO61310.1 - 0.00047 19.1 0.0 0.0013 17.6 0.0 1.7 1 1 1 2 2 2 1 Adenosine/AMP deaminase DUF1949 PF09186.6 AEO61311.1 - 0.21 11.1 1.1 0.65 9.6 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1949) Med18 PF09637.5 AEO61312.1 - 4.3e-17 62.5 0.0 4.9e-17 62.3 0.0 1.0 1 0 0 1 1 1 1 Med18 protein Fungal_trans_2 PF11951.3 AEO61313.1 - 1.1e-06 27.4 0.2 2.3e-06 26.4 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain CHMI PF02962.10 AEO61313.1 - 0.014 15.5 0.0 0.047 13.8 0.0 1.8 1 1 1 2 2 2 0 5-carboxymethyl-2-hydroxymuconate isomerase Fructosamin_kin PF03881.9 AEO61314.1 - 5.3e-74 248.7 0.0 5.6e-74 248.6 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 AEO61314.1 - 1.2e-07 31.6 0.0 1.7e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 AEO61314.1 - 0.15 10.7 0.0 0.22 10.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) RHD3 PF05879.7 AEO61315.1 - 0 1075.0 0.0 0 1074.8 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 AEO61315.1 - 1.7e-07 30.5 0.1 2.8e-07 29.8 0.1 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 AEO61315.1 - 6.4e-06 26.0 0.1 1.5e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Dynamin family AAA_28 PF13521.1 AEO61315.1 - 2.6e-05 24.2 0.0 0.0001 22.3 0.0 2.1 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 AEO61315.1 - 5.8e-05 23.0 0.0 0.00015 21.6 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 AEO61315.1 - 0.0042 17.5 0.0 0.0086 16.5 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Septin PF00735.13 AEO61315.1 - 0.03 13.3 0.0 0.054 12.5 0.0 1.4 1 0 0 1 1 1 0 Septin RNase_HII PF01351.13 AEO61316.1 - 2.4e-46 157.8 0.0 2.7e-41 141.3 0.0 2.1 2 0 0 2 2 2 2 Ribonuclease HII CobT PF06213.7 AEO61316.1 - 0.00036 19.7 0.4 0.00055 19.1 0.3 1.2 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT Nop14 PF04147.7 AEO61316.1 - 6.8 4.4 7.6 9.3 4.0 5.3 1.1 1 0 0 1 1 1 0 Nop14-like family Mif2_N PF15624.1 AEO61317.1 - 3.9e-38 131.1 0.9 3.9e-38 131.1 0.6 3.7 2 1 1 3 3 3 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal CENP-C_C PF11699.3 AEO61317.1 - 3.5e-33 113.4 0.4 5.4e-33 112.8 0.3 1.3 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.6 AEO61317.1 - 0.00031 20.1 0.0 0.00084 18.7 0.0 1.7 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 AEO61317.1 - 0.016 14.8 0.1 0.28 10.7 0.0 2.7 2 0 0 2 2 2 0 Cupin RNA12 PF10443.4 AEO61318.1 - 1.4e-168 560.9 1.9 4.2e-168 559.3 0.1 2.0 2 0 0 2 2 2 1 RNA12 protein RRM_1 PF00076.17 AEO61318.1 - 2.4e-06 27.0 0.0 3.1e-05 23.5 0.0 2.6 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO61318.1 - 0.0003 20.5 0.0 0.001 18.8 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO61318.1 - 0.0016 18.3 0.0 0.012 15.5 0.0 2.5 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF2487 PF10673.4 AEO61318.1 - 0.006 16.3 0.1 0.021 14.6 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2487) Arch_ATPase PF01637.13 AEO61318.1 - 0.025 14.2 0.0 0.21 11.2 0.0 2.3 1 1 0 1 1 1 0 Archaeal ATPase Strep_SA_rep PF06696.6 AEO61318.1 - 2.4 8.0 7.2 1.1 9.1 2.2 2.6 2 0 0 2 2 2 0 Streptococcal surface antigen repeat DUF3128 PF11326.3 AEO61319.1 - 9.6e-29 99.3 1.0 1.5e-28 98.6 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) DUF605 PF04652.11 AEO61319.1 - 0.02 14.2 16.1 0.025 14.0 11.1 1.1 1 0 0 1 1 1 0 Vta1 like HSP70 PF00012.15 AEO61320.1 - 1.6e-271 901.5 4.0 1.8e-271 901.4 2.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 AEO61320.1 - 1e-16 60.4 0.0 1.6e-15 56.5 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 AEO61320.1 - 0.00096 18.8 0.0 0.0029 17.2 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 AEO61320.1 - 0.012 14.7 0.1 0.049 12.7 0.0 1.9 1 1 1 2 2 2 0 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.15 AEO61320.1 - 0.047 12.9 0.0 2.8 7.1 0.0 2.5 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family FtsA PF14450.1 AEO61320.1 - 0.064 13.1 1.6 6.1 6.6 1.1 3.3 1 1 0 1 1 1 0 Cell division protein FtsA DLH PF01738.13 AEO61321.1 - 4.5e-27 94.7 0.0 5.6e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 AEO61321.1 - 1.1e-06 28.5 0.0 1.4e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 AEO61321.1 - 0.0011 18.7 0.0 0.0025 17.5 0.0 1.5 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.7 AEO61321.1 - 0.077 11.4 0.0 0.11 10.9 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.13 AEO61321.1 - 0.088 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) MS_channel PF00924.13 AEO61322.1 - 2.7e-20 72.6 2.8 4.5e-20 71.8 2.0 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 AEO61322.1 - 0.0056 15.9 0.2 0.013 14.7 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 AEO61322.1 - 0.0087 15.3 0.1 0.019 14.2 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 AEO61322.1 - 0.014 15.5 0.0 0.028 14.5 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.1 AEO61322.1 - 0.022 14.6 0.0 0.068 13.0 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain tRNA-synt_2b PF00587.20 AEO61323.1 - 1.8e-19 69.9 0.0 2.4e-19 69.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 AEO61323.1 - 2e-14 53.5 2.9 1e-13 51.2 2.0 2.0 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Ala_racemase_N PF01168.15 AEO61324.1 - 2.5e-41 141.6 0.0 3.1e-41 141.3 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain F-box-like PF12937.2 AEO61325.1 - 3.2e-05 23.5 0.7 3.2e-05 23.5 0.5 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 AEO61325.1 - 0.0065 16.0 1.4 0.0065 16.0 1.0 2.4 2 1 0 2 2 2 1 F-box domain Mo25 PF08569.6 AEO61327.1 - 7.6e-130 432.8 0.0 8.5e-130 432.6 0.0 1.0 1 0 0 1 1 1 1 Mo25-like KOW PF00467.24 AEO61328.1 - 6.2e-07 28.9 2.5 1.9e-06 27.3 1.7 1.8 1 0 0 1 1 1 1 KOW motif Sfi1 PF08457.5 AEO61329.1 - 8.2e-149 496.6 94.0 3.7e-146 487.8 59.5 2.0 1 1 1 2 2 2 2 Sfi1 spindle body protein tRNA-synt_1 PF00133.17 AEO61330.1 - 7.8e-224 744.1 0.0 1.3e-223 743.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 AEO61330.1 - 5.9e-27 94.2 0.0 2.1e-26 92.5 0.0 1.9 3 0 0 3 3 3 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 AEO61330.1 - 5.9e-19 67.9 1.4 4.4e-08 32.2 0.2 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 AEO61330.1 - 0.029 13.4 0.0 0.14 11.2 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain BLOC1_2 PF10046.4 AEO61331.1 - 0.16 12.1 0.5 0.38 10.9 0.1 1.7 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2826 PF11442.3 AEO61333.1 - 0.049 13.3 0.6 0.11 12.1 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2826) APC_CDC26 PF10471.4 AEO61333.1 - 0.63 10.8 0.1 0.63 10.8 0.0 3.4 4 0 0 4 4 4 0 Anaphase-promoting complex APC subunit 1 Pkinase PF00069.20 AEO61334.1 - 1.6e-69 233.9 0.0 2.1e-69 233.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO61334.1 - 9.8e-36 123.1 0.0 1.4e-35 122.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO61334.1 - 0.00015 20.8 0.4 0.032 13.2 0.0 2.8 2 1 0 2 2 2 2 Kinase-like APH PF01636.18 AEO61334.1 - 0.00046 19.9 0.2 0.01 15.5 0.0 2.5 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 AEO61334.1 - 0.00063 18.8 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 AEO61334.1 - 0.24 10.1 0.4 3.2 6.4 0.0 2.0 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase SWIB PF02201.13 AEO61335.1 - 1e-12 47.5 0.0 2e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain XPG_I PF00867.13 AEO61336.1 - 3.5e-25 87.8 0.0 8.3e-25 86.6 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 AEO61336.1 - 1.8e-07 31.3 0.0 4.1e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain Actin PF00022.14 AEO61337.1 - 1.2e-18 66.6 0.0 1.9e-17 62.7 0.0 2.5 2 1 0 2 2 2 1 Actin MGC-24 PF05283.6 AEO61340.1 - 0.057 13.1 1.2 0.073 12.8 0.8 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Abp2 PF09441.5 AEO61341.1 - 9.9e-93 308.9 0.0 1.5e-92 308.3 0.0 1.2 1 0 0 1 1 1 1 ARS binding protein 2 Mito_carr PF00153.22 AEO61342.1 - 1.4e-53 178.5 3.2 4.2e-18 64.8 0.4 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.11 AEO61342.1 - 0.00053 19.7 0.2 0.0015 18.3 0.2 1.8 1 0 0 1 1 1 1 UcrQ family Mak10 PF04112.8 AEO61343.1 - 6e-51 171.9 0.0 1e-50 171.2 0.0 1.4 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase XFP_C PF09363.5 AEO61343.1 - 0.081 12.3 0.1 0.16 11.3 0.1 1.4 1 0 0 1 1 1 0 XFP C-terminal domain Peptidase_M16 PF00675.15 AEO61344.1 - 7.6e-22 77.6 0.0 1.4e-21 76.8 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) ATP-synt_Eps PF04627.8 AEO61344.1 - 1.2e-20 72.7 3.9 1.2e-20 72.7 2.7 2.1 2 0 0 2 2 2 1 Mitochondrial ATP synthase epsilon chain Peptidase_M16_C PF05193.16 AEO61344.1 - 2.7e-13 49.9 0.0 2.2e-12 47.0 0.0 2.5 3 0 0 3 3 3 1 Peptidase M16 inactive domain RNA_pol_Rpc82 PF05645.8 AEO61345.1 - 5.1e-72 242.4 0.1 1.3e-71 241.1 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 AEO61345.1 - 1.5e-20 72.7 0.2 5.5e-18 64.5 0.0 3.2 3 0 0 3 3 3 1 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 AEO61345.1 - 1.8e-08 33.7 0.2 0.024 14.1 0.0 4.9 4 1 1 5 5 5 2 TFIIE alpha subunit YxiJ PF14176.1 AEO61345.1 - 0.011 15.8 0.0 0.43 10.7 0.0 2.5 2 0 0 2 2 2 0 YxiJ-like protein HTH_5 PF01022.15 AEO61345.1 - 0.016 14.8 0.1 0.8 9.4 0.0 3.4 3 0 0 3 3 3 0 Bacterial regulatory protein, arsR family Mito_carr PF00153.22 AEO61346.1 - 4.7e-29 99.9 0.3 2.5e-14 52.7 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein LRR_6 PF13516.1 AEO61347.1 - 2.6e-05 23.8 0.1 0.55 10.4 0.1 3.3 3 0 0 3 3 3 2 Leucine Rich repeat LRR_4 PF12799.2 AEO61347.1 - 0.0068 16.0 0.8 13 5.4 0.4 4.2 4 1 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 AEO61347.1 - 0.64 10.2 4.6 19 5.8 0.0 4.0 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_7 PF13504.1 AEO61347.1 - 1.3 9.5 3.3 25 5.6 0.1 4.1 4 0 0 4 4 4 0 Leucine rich repeat DUF605 PF04652.11 AEO61347.1 - 6.9 5.9 8.6 12 5.1 6.0 1.3 1 0 0 1 1 1 0 Vta1 like DUF377 PF04041.8 AEO61354.1 - 0.11 11.2 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF377) zf-C2H2 PF00096.21 AEO61355.1 - 1.4e-07 31.4 5.3 8.9e-05 22.6 1.1 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AEO61355.1 - 1.6e-05 24.8 3.7 6.6e-05 22.9 0.5 2.9 2 0 0 2 2 2 1 C2H2-type zinc finger GAT PF03127.9 AEO61355.1 - 0.011 15.6 0.3 0.027 14.4 0.1 1.6 2 0 0 2 2 2 0 GAT domain Hexapep PF00132.19 AEO61357.1 - 1e-08 34.2 0.1 0.0027 17.1 0.0 2.7 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 AEO61357.1 - 4e-06 27.0 0.0 6.4e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.18 AEO61357.1 - 0.00014 21.2 0.0 0.00034 20.0 0.0 1.6 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep_2 PF14602.1 AEO61357.1 - 0.018 14.6 5.1 0.43 10.1 1.6 3.1 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 AEO61357.1 - 0.18 10.3 0.7 0.43 9.0 0.5 1.5 1 1 0 1 1 1 0 L-fucokinase TruB_C PF09142.6 AEO61358.1 - 0.04 13.5 1.5 0.11 12.1 1.1 1.7 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal Spt20 PF12090.3 AEO61359.1 - 6e-46 156.0 0.0 6e-46 156.0 0.0 7.1 3 2 1 4 4 4 1 Spt20 family ATG27 PF09451.5 AEO61360.1 - 6.2e-63 212.5 0.0 1.2e-62 211.5 0.0 1.5 1 1 0 1 1 1 1 Autophagy-related protein 27 CobT PF06213.7 AEO61360.1 - 0.2 10.7 4.0 0.3 10.1 2.7 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT ECH PF00378.15 AEO61361.1 - 8.8e-19 67.5 0.0 1e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 AEO61361.1 - 0.00014 21.6 0.0 0.27 10.9 0.0 2.2 2 0 0 2 2 2 2 Peptidase family S49 Pam17 PF08566.5 AEO61362.1 - 0.041 13.5 0.0 0.081 12.6 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 Mito_fiss_reg PF05308.6 AEO61362.1 - 0.69 9.2 13.3 2 7.7 9.2 1.8 1 0 0 1 1 1 0 Mitochondrial fission regulator LRR_4 PF12799.2 AEO61364.1 - 8.3e-32 108.2 35.0 3.3e-07 29.7 1.1 8.6 4 2 6 10 10 10 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 AEO61364.1 - 2.6e-22 78.3 36.3 6.6e-07 28.9 1.7 6.6 3 2 4 7 7 7 6 Leucine rich repeat LRR_1 PF00560.28 AEO61364.1 - 5.7e-12 43.9 34.6 0.12 12.5 0.2 12.3 10 2 2 12 12 12 6 Leucine Rich Repeat LRR_9 PF14580.1 AEO61364.1 - 1.1e-06 28.3 9.0 0.01 15.4 0.1 3.6 2 1 2 4 4 4 2 Leucine-rich repeat LRR_7 PF13504.1 AEO61364.1 - 1.7e-05 24.2 43.0 4.5 7.9 0.9 12.3 13 1 1 14 14 14 5 Leucine rich repeat LRR_6 PF13516.1 AEO61364.1 - 0.00061 19.5 35.3 1.4 9.2 0.1 9.6 9 2 3 12 12 12 3 Leucine Rich repeat VWA PF00092.23 AEO61365.1 - 1.1e-08 34.9 0.0 2.9e-08 33.6 0.0 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 AEO61365.1 - 2.5e-07 30.9 0.0 4.4e-07 30.1 0.0 1.4 1 1 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 AEO61365.1 - 0.0011 18.8 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus Aminotran_1_2 PF00155.16 AEO61366.1 - 1.4e-37 129.5 0.0 1.6e-37 129.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 AEO61366.1 - 0.017 14.2 0.0 0.03 13.4 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase bZIP_2 PF07716.10 AEO61369.1 - 5.7e-11 42.0 10.8 5.7e-11 42.0 7.5 1.9 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 AEO61369.1 - 5.7e-05 22.9 8.0 5.7e-05 22.9 5.6 2.1 2 0 0 2 2 2 1 bZIP transcription factor XhlA PF10779.4 AEO61369.1 - 0.002 17.9 1.4 0.002 17.9 1.0 1.9 1 1 1 2 2 2 1 Haemolysin XhlA TSC22 PF01166.13 AEO61369.1 - 0.098 12.6 0.3 0.21 11.6 0.2 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family IncA PF04156.9 AEO61369.1 - 0.83 9.2 4.6 1.2 8.6 3.2 1.2 1 0 0 1 1 1 0 IncA protein CENP-N PF05238.8 AEO61370.1 - 3.2e-121 405.1 0.0 3.8e-121 404.9 0.0 1.1 1 0 0 1 1 1 1 Kinetochore protein CHL4 like TatD_DNase PF01026.16 AEO61371.1 - 7.8e-46 156.3 0.0 8.5e-40 136.5 0.0 2.3 2 0 0 2 2 2 2 TatD related DNase Pex14_N PF04695.8 AEO61371.1 - 0.032 14.2 4.6 0.078 13.0 3.2 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4557 PF15101.1 AEO61371.1 - 0.075 12.8 4.4 0.13 12.0 3.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) PIH1 PF08190.7 AEO61371.1 - 0.082 12.3 8.2 0.14 11.5 5.7 1.3 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Serinc PF03348.10 AEO61371.1 - 1.3 7.5 3.8 85 1.6 5.2 1.8 2 0 0 2 2 2 0 Serine incorporator (Serinc) DUF1764 PF08576.5 AEO61371.1 - 1.4 9.7 11.9 1.2 10.0 7.1 1.7 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Ribonuc_red_lgC PF02867.10 AEO61372.1 - 1.9e-221 736.3 0.0 2.6e-221 735.8 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 AEO61372.1 - 1.1e-23 82.8 0.0 2.7e-23 81.5 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 AEO61372.1 - 2.2e-17 63.2 0.2 7.2e-17 61.6 0.0 2.0 2 0 0 2 2 2 1 ATP cone domain MMR_HSR1_C PF08438.5 AEO61372.1 - 0.046 13.9 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 GTPase of unknown function C-terminal NRDD PF13597.1 AEO61372.1 - 0.063 11.3 0.0 0.1 10.6 0.0 1.2 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase CFEM PF05730.6 AEO61373.1 - 2.2e-09 36.9 2.4 4.2e-09 36.1 1.7 1.4 1 0 0 1 1 1 1 CFEM domain SOBP PF15279.1 AEO61373.1 - 2.6 8.3 5.4 3.4 7.9 3.7 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Pkinase PF00069.20 AEO61374.1 - 5.7e-53 179.7 0.1 9.6e-38 129.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AEO61374.1 - 4.2e-21 75.1 0.2 4.2e-19 68.6 0.1 3.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO61374.1 - 3.4e-05 22.9 0.0 8.6e-05 21.6 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 AEO61374.1 - 0.0016 18.2 1.1 0.0074 16.0 0.8 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Peptidase_C30 PF05409.8 AEO61374.1 - 0.33 9.9 0.0 0.54 9.2 0.0 1.2 1 0 0 1 1 1 0 Coronavirus endopeptidase C30 Glycos_transf_1 PF00534.15 AEO61375.1 - 4.6e-33 114.0 0.0 6e-32 110.4 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 AEO61375.1 - 2e-10 41.0 6.7 2e-10 41.0 4.6 2.9 2 1 0 3 3 3 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 AEO61375.1 - 5.5e-10 39.2 0.0 1.9e-09 37.4 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 AEO61375.1 - 4e-09 36.7 0.1 1.8e-07 31.3 0.1 2.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 AEO61375.1 - 5.2e-07 29.8 0.0 1.6e-06 28.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Tropomyosin PF00261.15 AEO61376.1 - 0.33 10.0 7.6 0.071 12.1 1.2 2.2 2 0 0 2 2 2 0 Tropomyosin Macoilin PF09726.4 AEO61376.1 - 0.53 8.4 4.9 0.086 11.1 0.8 1.5 2 0 0 2 2 2 0 Transmembrane protein RRM_1 PF00076.17 AEO61377.1 - 4.5e-43 144.7 1.1 2e-19 69.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO61377.1 - 2.9e-33 113.6 0.2 7.5e-18 64.2 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 AEO61377.1 - 4.3e-30 103.7 0.1 9.6e-30 102.6 0.0 1.6 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_5 PF13893.1 AEO61377.1 - 1.7e-21 75.8 0.0 2.8e-09 36.6 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 AEO61377.1 - 0.0018 18.0 0.5 0.046 13.5 0.0 2.8 3 1 0 3 3 3 1 RNA binding motif MIP-T3 PF10243.4 AEO61377.1 - 2.8 6.2 24.5 5.1 5.4 17.0 1.4 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Cyt-b5 PF00173.23 AEO61378.1 - 2e-21 75.5 0.2 1.2e-19 69.8 0.0 2.3 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 AEO61378.1 - 4.8e-08 33.3 24.6 4.8e-08 33.3 17.1 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily COX14 PF14880.1 AEO61378.1 - 0.13 11.9 4.1 0.074 12.6 0.9 1.9 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Het-C PF07217.6 AEO61379.1 - 8.2e-293 972.1 0.0 9.8e-293 971.9 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C PP2C PF00481.16 AEO61380.1 - 1.2e-34 119.8 0.0 6.4e-29 101.1 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C Pol_alpha_B_N PF08418.5 AEO61380.1 - 1.3 8.4 7.3 0.058 12.9 1.0 1.8 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal BTB PF00651.26 AEO61381.1 - 0.063 13.2 0.1 3.2 7.7 0.0 2.5 3 0 0 3 3 3 0 BTB/POZ domain HCO3_cotransp PF00955.16 AEO61382.1 - 8e-06 24.7 0.6 8.1e-06 24.7 0.4 1.0 1 0 0 1 1 1 1 HCO3- transporter family Methyltransf_18 PF12847.2 AEO61384.1 - 9.4e-10 39.0 0.1 1.3e-09 38.6 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO61384.1 - 1.7e-08 34.8 0.0 2.6e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO61384.1 - 3.3e-07 30.0 0.0 4.3e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO61384.1 - 4.6e-06 26.4 0.0 6.1e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO61384.1 - 9.9e-06 25.9 0.0 1.5e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO61384.1 - 1.2e-05 25.6 0.0 1.7e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO61384.1 - 0.0001 22.3 0.1 0.00017 21.5 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.20 AEO61384.1 - 0.00034 20.5 0.2 0.00056 19.8 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_16 PF10294.4 AEO61384.1 - 0.00063 19.2 0.0 0.00078 18.9 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 AEO61384.1 - 0.0022 17.4 0.0 0.0035 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain KR PF08659.5 AEO61384.1 - 0.018 14.7 0.5 0.037 13.6 0.3 1.4 1 1 0 1 1 1 0 KR domain Pkinase PF00069.20 AEO61385.1 - 2e-37 128.7 0.0 5.4e-37 127.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO61385.1 - 5.4e-19 68.2 0.0 8e-19 67.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 AEO61385.1 - 0.066 12.1 0.0 9.7 5.0 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Fungal_trans PF04082.13 AEO61387.1 - 3.6e-11 42.4 0.0 3e-09 36.1 0.0 3.0 3 1 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO61387.1 - 1.2e-07 31.5 11.8 2e-07 30.7 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RXT2_N PF08595.6 AEO61387.1 - 0.013 15.3 1.2 0.024 14.4 0.8 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Sigma70_ner PF04546.8 AEO61387.1 - 0.033 13.8 3.0 0.056 13.0 2.1 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region OMPdecase PF00215.19 AEO61388.1 - 8.4e-97 323.0 0.0 1e-96 322.7 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Sporozoite_P67 PF05642.6 AEO61388.1 - 0.008 14.1 0.5 0.01 13.7 0.3 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Bac_luciferase PF00296.15 AEO61388.1 - 0.026 13.6 1.9 0.046 12.8 1.0 1.6 2 0 0 2 2 2 0 Luciferase-like monooxygenase BAF1_ABF1 PF04684.8 AEO61388.1 - 0.033 13.0 6.4 0.045 12.6 4.5 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor CDP-OH_P_transf PF01066.16 AEO61389.1 - 7.6e-18 64.6 3.2 7.6e-18 64.6 2.2 1.7 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase SRP19 PF01922.12 AEO61390.1 - 1.1e-26 93.2 0.0 2.8e-26 91.9 0.0 1.7 1 0 0 1 1 1 1 SRP19 protein PAT1 PF09770.4 AEO61390.1 - 0.022 13.0 13.4 0.025 12.8 9.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Spt20 PF12090.3 AEO61390.1 - 0.18 11.1 4.8 0.28 10.4 3.3 1.3 1 0 0 1 1 1 0 Spt20 family Pex16 PF08610.5 AEO61390.1 - 0.46 9.4 3.6 0.7 8.8 2.5 1.3 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Pex14_N PF04695.8 AEO61390.1 - 0.61 10.1 10.4 1.3 9.0 7.2 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.9 AEO61390.1 - 0.84 9.3 8.3 1.2 8.8 5.8 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4557 PF15101.1 AEO61390.1 - 0.91 9.3 6.4 1.3 8.7 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF3408 PF11888.3 AEO61390.1 - 2 8.3 7.6 6.3 6.7 4.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) MCPVI PF02993.9 AEO61390.1 - 3.4 7.7 10.3 0.97 9.5 4.8 1.7 2 0 0 2 2 2 0 Minor capsid protein VI DUF605 PF04652.11 AEO61390.1 - 4.4 6.5 14.4 6.3 6.0 10.0 1.2 1 0 0 1 1 1 0 Vta1 like HMG_box PF00505.14 AEO61391.1 - 3.2e-19 68.9 1.3 9.9e-19 67.3 0.9 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 AEO61391.1 - 7.1e-05 23.1 0.9 0.00014 22.1 0.6 1.5 1 0 0 1 1 1 1 HMG-box domain TIP49 PF06068.8 AEO61392.1 - 8.8e-187 620.6 0.0 1e-186 620.4 0.0 1.0 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 AEO61392.1 - 7.2e-11 41.5 0.6 4.7e-07 29.0 0.0 3.2 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 AEO61392.1 - 8.5e-11 42.1 0.1 5.9e-07 29.7 0.1 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 AEO61392.1 - 2.9e-05 23.7 0.1 6.9e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 AEO61392.1 - 0.00016 21.8 0.2 0.79 9.8 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 AEO61392.1 - 0.00016 21.7 0.0 0.08 12.9 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_28 PF13521.1 AEO61392.1 - 0.0013 18.7 0.2 0.0053 16.7 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 AEO61392.1 - 0.0013 18.1 0.1 0.0062 15.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 AEO61392.1 - 0.0048 16.6 0.1 0.1 12.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 AEO61392.1 - 0.0054 15.8 0.3 0.013 14.5 0.2 1.6 1 0 0 1 1 1 1 Zeta toxin IstB_IS21 PF01695.12 AEO61392.1 - 0.01 15.2 0.2 0.022 14.1 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 AEO61392.1 - 0.012 14.7 0.1 0.31 10.1 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 AEO61392.1 - 0.015 14.8 0.1 0.76 9.2 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF2075 PF09848.4 AEO61392.1 - 0.015 14.3 0.0 0.068 12.1 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DnaB_C PF03796.10 AEO61392.1 - 0.028 13.3 0.0 0.054 12.3 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_18 PF13238.1 AEO61392.1 - 0.041 14.1 0.1 0.1 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 AEO61392.1 - 0.061 14.1 0.1 0.13 13.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain MinE PF03776.9 AEO61392.1 - 0.11 12.0 0.1 0.29 10.6 0.1 1.7 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE KaiC PF06745.8 AEO61392.1 - 0.12 11.4 0.8 0.49 9.4 0.1 2.1 2 0 0 2 2 2 0 KaiC EamA PF00892.15 AEO61393.1 - 1.2e-17 64.1 22.4 1.1e-10 41.6 3.6 2.9 2 1 1 3 3 3 2 EamA-like transporter family UAA PF08449.6 AEO61393.1 - 5.1e-05 22.3 9.2 0.0037 16.2 1.3 2.1 1 1 1 2 2 2 2 UAA transporter family EmrE PF13536.1 AEO61393.1 - 0.00018 21.7 24.3 0.0032 17.6 3.8 3.5 2 1 2 4 4 4 2 Multidrug resistance efflux transporter DUF872 PF05915.7 AEO61393.1 - 0.22 11.4 0.9 0.97 9.3 0.1 2.5 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF3021 PF11457.3 AEO61393.1 - 8.9 6.2 12.0 0.059 13.2 1.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3021) Macro PF01661.16 AEO61394.1 - 1.2e-17 63.8 0.0 2.3e-17 63.0 0.0 1.4 1 1 0 1 1 1 1 Macro domain TFIID-18kDa PF02269.11 AEO61395.1 - 5.7e-20 70.9 0.0 8.6e-20 70.3 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CENP-S PF15630.1 AEO61395.1 - 0.00012 22.2 0.0 0.00026 21.0 0.0 1.6 1 0 0 1 1 1 1 Kinetochore component CENP-S Bromo_TP PF07524.8 AEO61395.1 - 0.00027 20.6 0.0 0.00048 19.7 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated CBFD_NFYB_HMF PF00808.18 AEO61395.1 - 0.0013 18.7 0.0 0.0025 17.8 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 AEO61395.1 - 0.004 17.2 0.0 0.0072 16.4 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CD99L2 PF12301.3 AEO61395.1 - 0.031 13.9 2.6 0.038 13.6 1.8 1.2 1 0 0 1 1 1 0 CD99 antigen like protein 2 TFIID_20kDa PF03847.8 AEO61395.1 - 0.071 13.3 0.1 0.18 12.1 0.0 1.6 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A SPT6_acidic PF14632.1 AEO61395.1 - 0.44 10.7 10.3 0.79 9.9 7.1 1.5 1 0 0 1 1 1 0 Acidic N-terminal SPT6 DUF1242 PF06842.7 AEO61396.1 - 1.6e-19 69.0 2.7 2.3e-19 68.5 1.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) Tcp11 PF05794.8 AEO61397.1 - 6.6e-80 268.9 0.0 3e-77 260.2 0.1 2.1 2 0 0 2 2 2 2 T-complex protein 11 Borrelia_rep PF03183.8 AEO61397.1 - 1.6 8.6 4.3 0.6 10.0 0.1 2.4 2 0 0 2 2 2 0 Borrelia repeat protein HTH_29 PF13551.1 AEO61399.1 - 1.9e-05 24.7 0.0 3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 AEO61399.1 - 4.3e-05 23.0 0.0 7.8e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 AEO61399.1 - 0.0051 16.7 0.0 0.0093 15.9 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain RHH_4 PF13467.1 AEO61399.1 - 0.063 13.1 0.0 0.14 12.0 0.0 1.7 2 0 0 2 2 2 0 Ribbon-helix-helix domain HTH_Tnp_4 PF13613.1 AEO61399.1 - 0.12 11.9 0.1 0.12 11.9 0.1 1.7 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease Sigma70_r4 PF04545.11 AEO61399.1 - 0.12 11.6 0.1 0.32 10.3 0.0 1.8 2 0 0 2 2 2 0 Sigma-70, region 4 V_ATPase_I PF01496.14 AEO61400.1 - 1e-303 1009.0 0.0 1.2e-303 1008.8 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Filament PF00038.16 AEO61400.1 - 0.011 15.2 3.4 0.38 10.1 0.3 2.2 2 0 0 2 2 2 0 Intermediate filament protein DUF3584 PF12128.3 AEO61400.1 - 0.041 11.2 4.1 0.025 11.9 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF4140 PF13600.1 AEO61400.1 - 0.095 13.1 3.7 1.2 9.6 0.2 2.5 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) AAA_13 PF13166.1 AEO61400.1 - 0.28 9.5 1.5 0.97 7.8 0.3 1.9 2 0 0 2 2 2 0 AAA domain DivIC PF04977.10 AEO61400.1 - 0.7 9.4 4.0 0.83 9.1 0.2 2.8 2 0 0 2 2 2 0 Septum formation initiator DUF1515 PF07439.6 AEO61400.1 - 4.2 7.2 5.4 2.3 8.0 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1515) BCL9 PF11502.3 AEO61403.1 - 0.019 14.4 0.0 0.039 13.4 0.0 1.5 1 0 0 1 1 1 0 B-cell lymphoma 9 protein F-box-like PF12937.2 AEO61403.1 - 0.052 13.2 1.9 0.063 13.0 0.0 2.2 3 0 0 3 3 3 0 F-box-like LRR_6 PF13516.1 AEO61403.1 - 0.17 12.0 0.9 33 4.9 0.0 4.1 5 0 0 5 5 5 0 Leucine Rich repeat PHD PF00628.24 AEO61404.1 - 3.1e-10 39.5 7.8 5e-10 38.9 5.4 1.3 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 AEO61404.1 - 0.0001 22.5 4.8 0.00013 22.2 0.2 2.7 2 1 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding Prenyltransf PF01255.14 AEO61405.1 - 2.1e-89 298.5 0.0 5.4e-89 297.1 0.0 1.5 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase DUF1751 PF08551.5 AEO61406.1 - 6.6e-05 23.1 0.3 0.00012 22.3 0.2 1.4 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Gly-zipper_YMGG PF13441.1 AEO61406.1 - 0.05 13.1 1.1 5.6 6.5 0.0 2.4 2 0 0 2 2 2 0 YMGG-like Gly-zipper Rhomboid PF01694.17 AEO61406.1 - 0.073 13.0 5.5 0.019 14.9 1.1 2.1 2 1 0 2 2 2 0 Rhomboid family Gly-zipper_Omp PF13488.1 AEO61406.1 - 0.13 11.9 3.1 1 9.0 0.1 2.5 2 0 0 2 2 2 0 Glycine zipper Transgly_assoc PF04226.8 AEO61406.1 - 8.9 6.4 9.1 7.9 6.6 0.1 3.3 3 0 0 3 3 3 0 Transglycosylase associated protein Uds1 PF15456.1 AEO61407.1 - 8.4e-44 148.5 10.9 8.4e-44 148.5 7.6 7.8 4 2 4 8 8 8 1 Up-regulated During Septation IncA PF04156.9 AEO61407.1 - 0.00082 19.0 14.2 0.00082 19.0 9.9 8.3 4 2 3 7 7 7 2 IncA protein MOSC PF03473.12 AEO61407.1 - 0.0033 16.8 0.1 0.021 14.3 0.0 2.4 2 1 0 2 2 2 1 MOSC domain OST-HTH PF12872.2 AEO61407.1 - 0.051 13.4 0.2 16 5.3 0.0 3.3 2 0 0 2 2 2 0 OST-HTH/LOTUS domain CPSF73-100_C PF11718.3 AEO61408.1 - 4.9e-76 254.8 0.0 6.4e-74 247.9 0.0 2.2 2 0 0 2 2 2 2 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 AEO61408.1 - 4e-32 110.7 0.0 1.1e-31 109.4 0.0 1.7 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.22 AEO61408.1 - 1.2e-14 54.4 0.6 3.5e-14 52.9 0.4 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 AEO61408.1 - 1.1e-11 44.6 0.6 2e-11 43.7 0.4 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.7 AEO61408.1 - 2e-07 30.7 0.1 4.9e-07 29.4 0.1 1.7 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 AEO61408.1 - 1.8e-05 24.4 0.2 4.1e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF2360 PF10152.4 AEO61408.1 - 0.023 14.9 2.1 0.089 13.0 1.5 2.0 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) TAF4 PF05236.9 AEO61409.1 - 2.2e-07 30.4 10.2 0.00021 20.6 5.5 3.8 3 1 0 3 3 3 2 Transcription initiation factor TFIID component TAF4 family HTH_29 PF13551.1 AEO61410.1 - 0.049 13.7 0.1 0.06 13.4 0.1 1.1 1 0 0 1 1 1 0 Winged helix-turn helix P16-Arc PF04699.9 AEO61412.1 - 4.9e-60 201.9 0.0 5.9e-60 201.7 0.0 1.1 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) DUF2605 PF10792.4 AEO61412.1 - 0.083 12.5 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2605) LEAP-2 PF07359.6 AEO61412.1 - 0.089 12.4 1.5 0.33 10.6 0.3 2.5 2 1 1 3 3 3 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) Methyltransf_11 PF08241.7 AEO61413.1 - 5.2e-09 36.4 0.0 1.1e-08 35.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO61413.1 - 3e-08 34.0 0.0 5.9e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO61413.1 - 4.5e-07 29.7 0.0 9.2e-07 28.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO61413.1 - 0.00025 20.6 0.0 0.00078 19.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 AEO61413.1 - 0.021 13.9 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Adaptin_N PF01602.15 AEO61415.1 - 1.1e-65 221.9 3.1 1.5e-65 221.5 2.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 AEO61415.1 - 1.3e-48 163.5 0.0 3.5e-48 162.2 0.0 1.8 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 AEO61415.1 - 9e-20 71.1 0.0 1.9e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain AP4E_app_platf PF14807.1 AEO61415.1 - 0.048 13.8 0.0 0.13 12.5 0.0 1.8 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform WD40 PF00400.27 AEO61417.1 - 0.00012 21.8 2.0 0.06 13.2 0.0 3.0 4 0 0 4 4 4 2 WD domain, G-beta repeat PQQ_2 PF13360.1 AEO61417.1 - 0.0063 15.9 0.0 0.014 14.8 0.0 1.5 2 0 0 2 2 2 1 PQQ-like domain DSPc PF00782.15 AEO61418.1 - 1.1e-22 79.9 0.0 2.3e-20 72.5 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 AEO61418.1 - 0.00014 21.2 0.0 0.00084 18.7 0.0 2.0 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 AEO61418.1 - 0.17 11.9 0.0 2.9 7.9 0.1 2.2 2 0 0 2 2 2 0 Inositol hexakisphosphate FoP_duplication PF13865.1 AEO61418.1 - 1.3 9.5 3.3 2.7 8.4 2.3 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Thr_synth_N PF14821.1 AEO61419.1 - 6.2e-27 93.4 0.0 1.1e-26 92.6 0.0 1.5 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.20 AEO61419.1 - 2.9e-18 66.1 0.0 2.6e-17 63.0 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF4253 PF14062.1 AEO61419.1 - 0.11 12.1 0.0 13 5.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4253) Metallophos PF00149.23 AEO61420.1 - 3e-37 127.9 0.0 3.3e-32 111.5 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase NOSIC PF08060.8 AEO61420.1 - 0.027 14.2 0.0 0.074 12.8 0.0 1.7 2 0 0 2 2 2 0 NOSIC (NUC001) domain Smg4_UPF3 PF03467.10 AEO61421.1 - 5.7e-35 120.8 0.4 3.9e-34 118.1 0.0 2.5 2 1 0 2 2 2 1 Smg-4/UPF3 family RRM_1 PF00076.17 AEO61421.1 - 7.5e-09 35.1 0.8 1.7e-06 27.5 0.0 3.2 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO61421.1 - 1.3e-08 34.7 0.0 6.4e-07 29.2 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO61421.1 - 1.4e-05 24.8 0.0 5.6e-05 22.9 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Serglycin PF04360.7 AEO61421.1 - 0.00035 20.3 1.0 0.00035 20.3 0.7 2.1 2 0 0 2 2 2 1 Serglycin Nup35_RRM_2 PF14605.1 AEO61421.1 - 0.094 12.5 0.2 0.21 11.3 0.0 1.6 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DUF3450 PF11932.3 AEO61422.1 - 0.0092 15.2 11.5 0.0092 15.2 8.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3450) Mod_r PF07200.8 AEO61422.1 - 0.0095 15.8 5.4 0.0095 15.8 3.7 3.1 1 1 1 3 3 3 2 Modifier of rudimentary (Mod(r)) protein DUF4200 PF13863.1 AEO61422.1 - 0.011 15.6 18.3 0.011 15.6 12.7 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) Hormone_1 PF00103.15 AEO61422.1 - 0.6 9.4 15.1 0.87 8.8 0.1 2.6 2 1 1 3 3 3 0 Somatotropin hormone family SOBP PF15279.1 AEO61422.1 - 0.63 10.3 16.6 0.89 9.8 11.5 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Lectin_N PF03954.9 AEO61422.1 - 2.8 7.3 6.3 13 5.1 0.0 2.6 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain Sigma70_ner PF04546.8 AEO61422.1 - 3.4 7.2 34.2 0.084 12.4 4.7 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region CDC27 PF09507.5 AEO61422.1 - 7.5 5.6 42.8 11 5.0 29.7 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 HALZ PF02183.13 AEO61423.1 - 0.0034 17.0 34.0 0.29 10.8 1.4 5.5 4 1 2 6 6 6 3 Homeobox associated leucine zipper Shugoshin_N PF07558.6 AEO61423.1 - 0.014 15.0 22.9 0.61 9.8 3.5 4.9 4 1 0 4 4 4 0 Shugoshin N-terminal coiled-coil region DUF972 PF06156.8 AEO61423.1 - 0.024 14.9 21.3 0.61 10.4 1.6 4.5 2 2 2 4 4 4 0 Protein of unknown function (DUF972) ECIST_Cterm PF14784.1 AEO61423.1 - 0.035 14.0 0.5 13 5.8 0.0 2.7 1 1 1 2 2 2 0 C-terminal domain of the ECSIT protein TSC22 PF01166.13 AEO61423.1 - 0.058 13.3 22.9 1.8 8.5 1.2 5.0 3 1 2 5 5 5 0 TSC-22/dip/bun family TBPIP PF07106.8 AEO61423.1 - 0.11 12.0 12.8 0.17 11.4 2.0 2.2 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FlaC_arch PF05377.6 AEO61423.1 - 0.12 12.2 5.1 8.2 6.4 0.1 3.7 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) IncA PF04156.9 AEO61423.1 - 0.18 11.3 27.0 0.25 10.9 5.2 2.2 1 1 1 2 2 2 0 IncA protein Presenilin PF01080.12 AEO61423.1 - 0.21 10.3 0.4 0.37 9.5 0.1 1.3 1 1 0 1 1 1 0 Presenilin bZIP_1 PF00170.16 AEO61423.1 - 0.26 11.2 25.3 4 7.4 1.4 5.3 3 1 2 5 5 5 0 bZIP transcription factor NPV_P10 PF05531.7 AEO61423.1 - 0.35 11.1 6.0 4 7.7 0.2 2.7 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein APG6 PF04111.7 AEO61423.1 - 0.46 9.4 20.0 0.52 9.2 3.8 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF904 PF06005.7 AEO61423.1 - 0.61 10.4 30.4 5.3 7.4 1.2 4.4 2 2 1 3 3 3 0 Protein of unknown function (DUF904) DivIC PF04977.10 AEO61423.1 - 1.1 8.7 29.2 1.4 8.4 2.0 4.7 2 2 2 4 4 4 0 Septum formation initiator Tnp_P_element PF12017.3 AEO61423.1 - 1.7 7.8 5.1 1.6 7.8 0.1 2.5 1 1 1 2 2 2 0 Transposase protein DUF4201 PF13870.1 AEO61423.1 - 1.9 7.8 22.4 0.76 9.1 5.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) Cortex-I_coil PF09304.5 AEO61423.1 - 2 8.5 25.2 0.085 12.9 5.4 3.0 2 1 0 2 2 2 0 Cortexillin I, coiled coil OmpH PF03938.9 AEO61423.1 - 2.3 8.1 14.4 0.42 10.5 1.3 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) TMF_DNA_bd PF12329.3 AEO61423.1 - 3.6 7.4 23.9 0.23 11.2 2.5 3.9 2 2 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF3166 PF11365.3 AEO61423.1 - 4.6 7.7 15.1 0.81 10.1 2.5 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3166) GAS PF13851.1 AEO61423.1 - 4.7 6.3 22.3 5.5 6.1 4.4 2.5 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding CedA PF10729.4 AEO61423.1 - 5.1 6.7 7.9 8.3 6.0 0.2 2.9 2 1 1 3 3 2 0 Cell division activator CedA Spc7 PF08317.6 AEO61423.1 - 5.3 5.6 16.2 5.3 5.6 3.0 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein Syntaxin PF00804.20 AEO61423.1 - 5.3 7.2 10.0 1.6 8.9 1.8 2.6 2 0 0 2 2 2 0 Syntaxin Mnd1 PF03962.10 AEO61423.1 - 5.9 6.4 14.6 1.9 8.0 2.1 2.4 2 0 0 2 2 2 0 Mnd1 family DUF4391 PF14335.1 AEO61423.1 - 7.7 5.8 9.7 5.9 6.2 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4391) Aldedh PF00171.17 AEO61425.1 - 1.3e-190 633.7 0.1 1.4e-190 633.5 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TRF PF08558.5 AEO61426.1 - 1.5e-52 178.3 0.1 2.1e-52 177.8 0.1 1.2 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 AEO61426.1 - 6.7e-06 26.0 0.0 1.2e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 AEO61426.1 - 0.022 14.8 0.3 0.064 13.3 0.0 1.9 2 0 0 2 2 2 0 Myb-like DNA-binding domain MFS_1 PF07690.11 AEO61428.1 - 9.3e-10 37.7 8.5 1.1e-09 37.5 5.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO61428.1 - 0.038 12.5 3.0 0.045 12.3 2.1 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter DUF4191 PF13829.1 AEO61428.1 - 0.19 10.8 1.8 0.24 10.5 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Band_7 PF01145.20 AEO61429.1 - 3.7e-28 98.6 2.2 5.5e-28 98.0 1.5 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 AEO61429.1 - 0.073 12.5 0.5 0.12 11.8 0.3 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family DEAD PF00270.24 AEO61430.1 - 9.4e-34 116.3 0.0 2.8e-33 114.7 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 AEO61430.1 - 7.4e-21 73.4 0.0 1.5e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 AEO61430.1 - 1.3e-19 69.8 0.0 3.1e-19 68.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AEO61430.1 - 0.0013 18.5 0.3 0.013 15.3 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit CAF-1_p150 PF11600.3 AEO61430.1 - 0.61 9.4 29.1 0.98 8.7 20.2 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal CTP_transf_1 PF01148.15 AEO61431.1 - 5e-17 62.4 4.9 5e-13 49.3 0.4 2.1 1 1 1 2 2 2 2 Cytidylyltransferase family Sod_Fe_N PF00081.17 AEO61431.1 - 0.073 13.3 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain KxDL PF10241.4 AEO61433.1 - 6.5e-32 109.2 2.6 9e-32 108.8 1.8 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein Mating_C PF12737.2 AEO61433.1 - 0.18 10.6 8.6 0.34 9.7 1.2 2.3 2 1 0 2 2 2 0 C-terminal domain of homeodomain 1 Pap_E4 PF02711.9 AEO61435.1 - 1.1 10.1 3.6 1.9 9.3 2.5 1.4 1 0 0 1 1 1 0 E4 protein Cir_N PF10197.4 AEO61436.1 - 0.0058 16.6 0.7 0.0058 16.6 0.5 4.7 2 1 1 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR AAA PF00004.24 AEO61437.1 - 1.3e-49 167.8 0.0 5.2e-39 133.4 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AEO61437.1 - 2.6e-11 43.7 0.1 0.00034 20.7 0.0 3.9 2 2 0 2 2 2 2 AAA domain CDC48_2 PF02933.12 AEO61437.1 - 6.3e-10 38.5 0.3 1.4e-08 34.2 0.1 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 CDC48_N PF02359.13 AEO61437.1 - 7.2e-09 35.4 0.0 1.4e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain TIP49 PF06068.8 AEO61437.1 - 2e-08 33.4 0.0 0.0016 17.2 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_16 PF13191.1 AEO61437.1 - 3.5e-08 33.6 0.0 0.0057 16.6 0.0 2.6 2 1 0 2 2 2 2 AAA ATPase domain AAA_19 PF13245.1 AEO61437.1 - 7.2e-08 32.0 0.1 0.02 14.6 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain AAA_17 PF13207.1 AEO61437.1 - 1.5e-07 32.2 0.0 0.015 16.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 AEO61437.1 - 1.7e-07 31.1 0.0 0.011 15.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 AEO61437.1 - 9.3e-07 28.8 0.0 0.013 15.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.7 AEO61437.1 - 9.7e-07 28.0 0.3 0.026 13.5 0.0 2.6 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 AEO61437.1 - 2.1e-06 28.0 0.0 0.037 14.3 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.9 AEO61437.1 - 3.1e-06 26.9 0.0 0.0016 18.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 AEO61437.1 - 9.9e-06 24.8 0.3 0.0047 16.1 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_2 PF07724.9 AEO61437.1 - 1.3e-05 25.2 0.0 0.00011 22.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 AEO61437.1 - 1.6e-05 24.3 1.5 0.48 9.7 0.0 3.7 2 2 0 4 4 4 2 AAA domain Zeta_toxin PF06414.7 AEO61437.1 - 5.4e-05 22.3 0.0 0.067 12.2 0.0 2.2 2 0 0 2 2 2 2 Zeta toxin IstB_IS21 PF01695.12 AEO61437.1 - 6e-05 22.5 0.1 0.15 11.4 0.0 2.7 3 0 0 3 3 3 2 IstB-like ATP binding protein KaiC PF06745.8 AEO61437.1 - 0.00015 20.9 0.1 0.022 13.8 0.2 2.3 2 0 0 2 2 2 1 KaiC RNA_helicase PF00910.17 AEO61437.1 - 0.00016 21.8 0.0 0.08 13.1 0.0 2.6 2 0 0 2 2 2 1 RNA helicase ABC_tran PF00005.22 AEO61437.1 - 0.0012 19.1 0.0 0.053 13.8 0.1 2.4 2 0 0 2 2 2 1 ABC transporter AAA_24 PF13479.1 AEO61437.1 - 0.0014 18.3 0.2 0.067 12.7 0.2 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 AEO61437.1 - 0.002 17.8 0.1 1.4 8.5 0.0 2.7 3 0 0 3 3 2 1 NACHT domain AAA_28 PF13521.1 AEO61437.1 - 0.0025 17.8 0.0 1.4 8.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 AEO61437.1 - 0.0042 16.3 0.0 2.2 7.4 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein Sigma54_activat PF00158.21 AEO61437.1 - 0.0043 16.5 0.0 1.2 8.5 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain Arch_ATPase PF01637.13 AEO61437.1 - 0.0047 16.6 0.3 25 4.4 0.0 3.2 2 1 1 3 3 3 0 Archaeal ATPase AAA_11 PF13086.1 AEO61437.1 - 0.005 16.4 0.0 1.6 8.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 AEO61437.1 - 0.0056 15.9 0.0 2.2 7.4 0.0 2.3 2 0 0 2 2 2 1 Chromatin associated protein KTI12 Parvo_NS1 PF01057.12 AEO61437.1 - 0.007 15.2 0.0 1.1 8.0 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_3 PF07726.6 AEO61437.1 - 0.0081 15.7 0.0 0.43 10.1 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 AEO61437.1 - 0.013 14.3 0.0 1.4 7.7 0.1 2.2 2 0 0 2 2 2 0 NB-ARC domain UPF0079 PF02367.12 AEO61437.1 - 0.019 14.5 0.0 2.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 CPT PF07931.7 AEO61437.1 - 0.042 13.4 0.0 0.28 10.7 0.0 2.1 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein DUF2075 PF09848.4 AEO61437.1 - 0.074 12.0 0.0 0.52 9.2 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 AEO61437.1 - 0.14 11.7 0.0 1.5 8.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain RasGEF PF00617.14 AEO61439.1 - 9.4e-51 172.2 0.1 1.3e-50 171.7 0.0 1.2 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 AEO61439.1 - 2.4e-14 53.2 0.3 4.5e-14 52.4 0.2 1.4 1 0 0 1 1 1 1 RasGEF N-terminal motif HD_2 PF12917.2 AEO61439.1 - 0.52 10.0 0.0 0.95 9.2 0.0 1.3 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme Ribosomal_S2 PF00318.15 AEO61440.1 - 1.2e-43 148.7 0.0 7.5e-23 80.8 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Ribosomal_S15 PF00312.17 AEO61441.1 - 1.2e-15 57.0 0.1 1.8e-14 53.2 0.0 2.3 2 0 0 2 2 2 1 Ribosomal protein S15 Sec8_exocyst PF04048.9 AEO61441.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Vir_act_alpha_C PF10400.4 AEO61441.1 - 0.18 12.1 0.3 0.18 12.1 0.2 2.7 3 0 0 3 3 3 0 Virulence activator alpha C-term vATP-synt_AC39 PF01992.11 AEO61442.1 - 1.8e-122 408.6 0.0 2.1e-122 408.4 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit DHHA1 PF02272.14 AEO61442.1 - 0.075 12.7 4.4 0.067 12.8 1.4 2.1 2 0 0 2 2 2 0 DHHA1 domain Nop PF01798.13 AEO61443.1 - 2.5e-53 179.4 1.3 5.3e-53 178.3 0.9 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 AEO61443.1 - 8.5e-26 89.5 0.1 1.7e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 AEO61443.1 - 1.7e-20 72.9 1.2 1.7e-20 72.9 0.9 2.5 2 0 0 2 2 2 1 NOP5NT (NUC127) domain ubiquitin PF00240.18 AEO61444.1 - 9.4e-05 21.7 0.0 0.00014 21.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family DUF1777 PF08648.7 AEO61444.1 - 0.00076 19.2 58.0 0.00076 19.2 40.2 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF1777) MIP-T3 PF10243.4 AEO61444.1 - 0.59 8.5 24.3 0.72 8.2 16.8 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 zf-HIT PF04438.11 AEO61445.1 - 3.5e-10 39.3 9.1 5.3e-10 38.7 6.3 1.3 1 0 0 1 1 1 1 HIT zinc finger Perilipin PF03036.11 AEO61446.1 - 9.4e-05 21.4 0.0 0.00012 21.0 0.0 1.2 1 0 0 1 1 1 1 Perilipin family Pirin PF02678.11 AEO61447.1 - 6.6e-33 112.7 0.0 7.4e-32 109.4 0.0 2.4 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.8 AEO61447.1 - 2.9e-22 78.7 0.0 4.5e-21 74.8 0.0 2.5 2 1 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 AEO61447.1 - 5.8e-09 35.3 2.2 2.7e-06 26.7 0.4 2.5 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 AEO61447.1 - 0.047 13.0 0.2 0.39 10.1 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF861) Sugar-bind PF04198.8 AEO61447.1 - 0.13 11.1 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Putative sugar-binding domain Med19 PF10278.4 AEO61448.1 - 0.037 13.7 17.0 0.18 11.4 10.2 2.1 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Herpes_DNAp_acc PF04929.7 AEO61448.1 - 1.2 7.9 7.0 1.8 7.4 4.9 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor RNase_H2-Ydr279 PF09468.5 AEO61448.1 - 1.9 7.6 12.2 2.6 7.1 8.4 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Peptidase_S49_N PF08496.5 AEO61448.1 - 4.5 7.0 9.8 6.6 6.5 6.8 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Neur_chan_memb PF02932.11 AEO61448.1 - 5.2 6.8 5.4 2.4 7.9 2.1 1.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region FancD2 PF14631.1 AEO61448.1 - 6.2 3.7 5.8 8.5 3.3 4.0 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Phosphoesterase PF04185.9 AEO61449.1 - 1.2e-24 87.2 0.3 3e-24 85.9 0.2 1.6 1 1 0 1 1 1 1 Phosphoesterase family Fungal_trans PF04082.13 AEO61450.1 - 2.9e-15 55.8 1.0 5e-15 55.0 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO61450.1 - 6e-08 32.4 7.7 1.2e-07 31.4 5.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2470 PF10615.4 AEO61451.1 - 1.9e-15 56.8 0.1 2.6e-14 53.2 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2470) OMP_b-brl PF13505.1 AEO61451.1 - 0.35 10.7 2.4 0.72 9.7 1.6 1.5 1 0 0 1 1 1 0 Outer membrane protein beta-barrel domain Gly-zipper_OmpA PF13436.1 AEO61451.1 - 1.5 8.4 10.4 1.1 8.9 2.9 2.5 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain zf-H2C2_2 PF13465.1 AEO61453.1 - 1.7e-20 72.2 22.4 1.1e-06 28.6 2.8 4.1 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 AEO61453.1 - 7.8e-13 47.9 39.7 4.8e-05 23.4 2.6 4.9 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AEO61453.1 - 7.8e-05 22.7 32.8 0.26 11.7 2.6 5.0 4 0 0 4 4 4 4 C2H2-type zinc finger EF-hand_6 PF13405.1 AEO61454.1 - 5.9e-10 38.1 0.8 0.00058 19.5 0.2 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 AEO61454.1 - 9.1e-09 35.3 0.4 1.5e-08 34.6 0.3 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 AEO61454.1 - 3.7e-06 25.8 0.5 0.00071 18.7 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.1 AEO61454.1 - 4.1e-06 25.8 0.3 0.00042 19.5 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 AEO61454.1 - 9.9e-05 21.8 0.7 0.0052 16.3 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair DUF3164 PF11363.3 AEO61454.1 - 0.048 13.0 0.4 0.069 12.5 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3164) Met_10 PF02475.11 AEO61455.1 - 0.00013 21.6 0.0 0.00073 19.1 0.0 1.9 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_26 PF13659.1 AEO61455.1 - 0.033 14.2 0.0 0.067 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Abhydrolase_6 PF12697.2 AEO61457.1 - 2.2e-25 89.8 5.2 4.9e-25 88.7 3.6 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO61457.1 - 1.9e-14 53.6 0.1 4.2e-14 52.5 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO61457.1 - 6.3e-06 25.9 0.0 1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 AEO61457.1 - 7.9e-06 25.6 0.1 2.4e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 AEO61457.1 - 4.8e-05 22.6 0.4 0.00011 21.4 0.1 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 AEO61457.1 - 0.017 14.7 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 AEO61457.1 - 0.051 13.1 0.0 0.089 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DBR1 PF05011.8 AEO61458.1 - 7.2e-53 178.3 0.0 1.3e-52 177.5 0.0 1.4 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 AEO61458.1 - 1.4e-09 37.6 0.5 3.1e-09 36.5 0.3 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Skp1_POZ PF03931.10 AEO61459.1 - 5.6e-13 48.7 0.0 7.9e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Ras PF00071.17 AEO61460.1 - 4.1e-48 162.8 0.0 5.1e-48 162.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AEO61460.1 - 7.9e-12 45.7 0.0 1.2e-11 45.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AEO61460.1 - 8.8e-06 25.0 0.0 2.3e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family DASH_Dad1 PF08649.5 AEO61461.1 - 3.1e-25 87.6 1.0 3.9e-25 87.3 0.7 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 DASH_Dad4 PF08650.5 AEO61461.1 - 0.019 14.8 0.2 0.025 14.4 0.2 1.1 1 0 0 1 1 1 0 DASH complex subunit Dad4 Glutaredoxin2_C PF04399.8 AEO61461.1 - 0.033 13.7 0.1 0.041 13.4 0.1 1.2 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain WVELL PF14043.1 AEO61461.1 - 0.07 12.7 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 WVELL protein PilJ PF13675.1 AEO61461.1 - 0.092 13.0 0.2 0.1 12.9 0.1 1.1 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Prefoldin_2 PF01920.15 AEO61462.1 - 2e-26 91.8 4.8 3e-26 91.2 3.3 1.2 1 0 0 1 1 1 1 Prefoldin subunit FTA4 PF13093.1 AEO61462.1 - 0.065 12.6 2.8 0.076 12.4 1.9 1.2 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 AAA_23 PF13476.1 AEO61462.1 - 0.3 11.3 5.1 0.39 11.0 3.5 1.1 1 0 0 1 1 1 0 AAA domain MtrG PF04210.8 AEO61462.1 - 0.98 9.1 3.7 0.75 9.5 0.1 2.2 2 1 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G Rho_Binding PF08912.6 AEO61462.1 - 7.4 6.9 13.2 0.35 11.1 0.2 2.8 2 1 1 3 3 3 0 Rho Binding CBFD_NFYB_HMF PF00808.18 AEO61463.1 - 2.9e-05 24.0 0.2 3.9e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Herpes_U59 PF04529.7 AEO61464.1 - 0.038 12.8 0.6 0.053 12.3 0.4 1.1 1 0 0 1 1 1 0 Herpesvirus U59 protein API5 PF05918.6 AEO61464.1 - 0.084 11.3 10.1 0.0086 14.6 3.7 1.7 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) DUF3963 PF13124.1 AEO61464.1 - 0.27 11.0 0.2 0.46 10.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) GRP PF07172.6 AEO61464.1 - 0.69 10.4 17.4 0.22 12.0 9.6 2.1 2 0 0 2 2 2 0 Glycine rich protein family DUF4404 PF14357.1 AEO61464.1 - 3.4 8.1 16.6 0.11 12.9 4.6 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4404) FlxA PF14282.1 AEO61464.1 - 6.4 6.7 19.1 12 5.9 6.5 3.7 2 1 2 4 4 4 0 FlxA-like protein DNA_binding_1 PF01035.15 AEO61465.1 - 3.7e-25 87.4 0.0 4.7e-25 87.1 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain DENN PF02141.16 AEO61466.1 - 4.5e-40 137.3 0.0 7.8e-40 136.5 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 AEO61466.1 - 1.4e-05 24.9 0.3 5e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 uDENN domain Dfp1_Him1_M PF08630.5 AEO61466.1 - 0.18 11.5 1.6 1.5 8.6 1.2 2.2 2 0 0 2 2 2 0 Dfp1/Him1, central region Elongin_A PF06881.6 AEO61466.1 - 3.1 8.2 11.3 0.082 13.2 2.8 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF2570 PF10828.3 AEO61466.1 - 4.4 6.9 10.8 3.3 7.3 5.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) DivIVA PF05103.8 AEO61466.1 - 5.5 7.0 16.9 1.8 8.6 5.5 2.7 1 1 1 2 2 2 0 DivIVA protein Occludin_ELL PF07303.8 AEO61466.1 - 6.9 7.4 10.0 4.6 8.0 0.4 2.5 1 1 0 2 2 2 0 Occludin homology domain TMF_TATA_bd PF12325.3 AEO61466.1 - 9.3 6.0 17.9 9.7 5.9 2.5 2.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding LSM14 PF12701.2 AEO61467.1 - 7.7e-34 115.3 0.0 1.5e-33 114.4 0.0 1.5 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 AEO61467.1 - 2.5e-19 69.7 0.4 2.5e-19 69.7 0.3 2.0 2 0 0 2 2 2 1 FDF domain SM-ATX PF14438.1 AEO61467.1 - 1.8e-05 24.5 0.0 3.2e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain Tcf25 PF04910.9 AEO61468.1 - 1.3e-74 251.2 0.1 2.1e-74 250.6 0.1 1.3 1 0 0 1 1 1 1 Transcriptional repressor TCF25 NST1 PF13945.1 AEO61468.1 - 0.74 9.8 10.3 0.31 11.0 5.1 1.8 2 0 0 2 2 2 0 Salt tolerance down-regulator Nop53 PF07767.6 AEO61468.1 - 7.6 5.4 22.7 0.32 9.9 11.4 1.9 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) HMA PF00403.21 AEO61469.1 - 9e-16 57.7 0.4 1.5e-15 57.0 0.3 1.3 1 0 0 1 1 1 1 Heavy-metal-associated domain Fungal_trans PF04082.13 AEO61470.1 - 3e-16 59.0 0.2 4.4e-16 58.5 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_1_2 PF00155.16 AEO61472.1 - 1.7e-65 221.3 0.0 1.9e-65 221.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 AEO61472.1 - 2.9e-06 26.5 0.0 5.4e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 AEO61472.1 - 2.3e-05 23.6 0.0 3.6e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 AEO61472.1 - 0.0005 18.4 0.0 0.00095 17.5 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 AEO61472.1 - 0.0012 17.7 0.0 0.0026 16.5 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V Ras PF00071.17 AEO61473.1 - 1.1e-10 41.1 0.0 1.5e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 AEO61473.1 - 1.2e-06 28.4 0.0 2.3e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 AEO61473.1 - 2.2e-06 28.1 0.0 3.7e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 AEO61473.1 - 7.4e-06 25.2 0.0 1.3e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 AEO61473.1 - 0.00053 19.2 0.0 0.00081 18.7 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 AEO61473.1 - 0.0012 18.7 0.0 0.0085 15.9 0.0 2.1 1 1 1 2 2 2 1 Dynamin family IIGP PF05049.8 AEO61473.1 - 0.015 14.1 0.2 0.045 12.5 0.2 1.7 1 1 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_16 PF13191.1 AEO61473.1 - 0.015 15.2 0.1 0.034 14.1 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.1 AEO61473.1 - 0.015 14.8 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 AEO61473.1 - 0.016 15.5 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter DUF258 PF03193.11 AEO61473.1 - 0.017 14.2 0.0 0.028 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Arf PF00025.16 AEO61473.1 - 0.051 12.8 0.0 0.071 12.3 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family PduV-EutP PF10662.4 AEO61473.1 - 0.08 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 AEO61473.1 - 0.1 12.2 0.0 0.34 10.5 0.0 1.8 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.7 AEO61473.1 - 0.16 11.0 0.1 0.26 10.3 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.9 AEO61473.1 - 0.16 11.6 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF2407_C PF13373.1 AEO61474.1 - 2.7e-27 95.3 0.0 4.6e-27 94.6 0.0 1.4 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.4 AEO61474.1 - 1.7e-22 79.4 0.0 4.5e-22 78.0 0.0 1.8 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain GRP PF07172.6 AEO61474.1 - 0.021 15.3 9.0 0.071 13.5 6.2 1.9 1 0 0 1 1 1 0 Glycine rich protein family Pneumo_att_G PF05539.6 AEO61474.1 - 1.8 7.8 7.5 2.8 7.2 5.2 1.3 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G rRNA_proc-arch PF13234.1 AEO61475.1 - 6.2e-88 294.4 0.0 1.5e-87 293.1 0.0 1.7 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 AEO61475.1 - 3.3e-57 192.6 2.7 6.2e-57 191.7 1.9 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 AEO61475.1 - 1.1e-21 77.1 0.0 3.7e-21 75.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO61475.1 - 3e-08 33.3 0.0 6.4e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 AEO61475.1 - 0.00098 18.9 0.0 0.016 15.0 0.0 2.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit T2SE PF00437.15 AEO61475.1 - 0.01 14.7 0.0 0.061 12.2 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein Prp19 PF08606.6 AEO61475.1 - 0.13 11.9 1.3 2.4 7.9 0.2 2.6 2 0 0 2 2 2 0 Prp19/Pso4-like Steroid_dh PF02544.11 AEO61476.1 - 2.4e-22 79.3 0.0 4.3e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 AEO61476.1 - 5.3e-05 23.2 0.1 0.00014 21.9 0.1 1.8 1 1 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.7 AEO61476.1 - 9.8e-05 21.7 0.2 0.00013 21.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) GCN5L1 PF06320.8 AEO61477.1 - 9.6e-10 38.3 2.1 1.6e-09 37.6 1.5 1.3 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) IncA PF04156.9 AEO61477.1 - 0.034 13.7 0.6 0.055 13.0 0.4 1.3 1 0 0 1 1 1 0 IncA protein FlgN PF05130.7 AEO61477.1 - 0.073 13.3 4.1 0.14 12.4 2.9 1.4 1 0 0 1 1 1 0 FlgN protein SOG2 PF10428.4 AEO61478.1 - 2.4e-110 369.2 1.2 2.4e-110 369.2 0.8 2.1 2 0 0 2 2 2 1 RAM signalling pathway protein LRR_8 PF13855.1 AEO61478.1 - 1.9e-20 72.3 10.1 1.8e-10 40.3 0.1 3.0 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 AEO61478.1 - 2e-16 59.1 4.4 5.8e-06 25.8 0.0 3.9 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 AEO61478.1 - 2.3e-09 35.9 3.9 0.84 9.9 0.1 5.9 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 AEO61478.1 - 5.6e-05 22.6 5.2 8.5 7.0 0.0 5.0 4 0 0 4 4 4 3 Leucine rich repeat LRR_6 PF13516.1 AEO61478.1 - 2.4 8.4 5.4 41 4.6 0.0 4.1 5 0 0 5 5 5 0 Leucine Rich repeat DEAD PF00270.24 AEO61479.1 - 9.6e-19 67.4 0.0 3.1e-18 65.8 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO61479.1 - 2.7e-17 62.4 0.0 1.2e-15 57.1 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 AEO61479.1 - 0.076 11.7 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain Ydc2-catalyt PF09159.5 AEO61480.1 - 2.2e-56 191.3 0.0 2.6e-56 191.1 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 SAP PF02037.22 AEO61480.1 - 3.7e-06 26.3 0.2 9e-06 25.0 0.1 1.6 1 0 0 1 1 1 1 SAP domain Pox_A22 PF04848.8 AEO61480.1 - 0.028 14.2 0.0 5 6.9 0.0 3.0 3 0 0 3 3 3 0 Poxvirus A22 protein FliX PF10768.4 AEO61480.1 - 1.1 9.4 9.2 2.3 8.4 0.2 3.1 3 0 0 3 3 3 0 Class II flagellar assembly regulator Ribosomal_60s PF00428.14 AEO61480.1 - 2.7 8.4 22.1 0.091 13.1 8.9 2.9 3 0 0 3 3 3 0 60s Acidic ribosomal protein Pyr_redox_2 PF07992.9 AEO61481.1 - 2.7e-39 135.1 0.4 8e-39 133.6 0.3 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 AEO61481.1 - 1.3e-33 115.3 0.4 6.8e-33 112.9 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 AEO61481.1 - 1.7e-18 66.8 6.0 1.9e-17 63.3 0.1 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AEO61481.1 - 3e-11 43.7 0.2 2.8e-08 34.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 AEO61481.1 - 7.7e-05 21.7 0.1 0.0036 16.2 0.0 2.6 2 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.2 AEO61481.1 - 0.00017 20.8 0.6 0.00035 19.7 0.2 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 AEO61481.1 - 0.00041 19.9 1.4 0.69 9.4 0.0 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.19 AEO61481.1 - 0.00075 18.5 0.6 0.015 14.2 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 AEO61481.1 - 0.0012 17.8 0.4 0.0041 16.0 0.2 2.0 3 0 0 3 3 3 1 Glucose inhibited division protein A HI0933_like PF03486.9 AEO61481.1 - 0.0013 17.3 7.4 0.47 8.8 1.3 3.1 2 1 0 3 3 3 2 HI0933-like protein FAD_binding_2 PF00890.19 AEO61481.1 - 0.0039 16.0 8.7 0.12 11.2 0.1 2.4 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 AEO61481.1 - 0.0093 15.0 0.2 0.019 14.0 0.1 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 AEO61481.1 - 0.11 12.5 1.9 0.3 11.1 1.3 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 AEO61481.1 - 0.27 10.8 0.0 0.27 10.8 0.0 3.1 4 0 0 4 4 4 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain COX7C PF02935.11 AEO61482.1 - 3.8e-15 55.4 0.8 5.2e-15 54.9 0.5 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Deltaretro_Tax PF05599.6 AEO61482.1 - 0.027 14.7 0.4 0.039 14.2 0.2 1.3 1 0 0 1 1 1 0 Deltaretrovirus Tax protein Sec6 PF06046.8 AEO61483.1 - 1.2e-164 548.5 7.1 1.7e-164 548.0 5.0 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec6 Vps53_N PF04100.7 AEO61483.1 - 0.0053 15.5 2.2 0.0053 15.5 1.5 2.1 2 1 0 2 2 2 1 Vps53-like, N-terminal DUF2450 PF10475.4 AEO61483.1 - 0.03 13.2 0.5 0.09 11.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) OmdA PF13376.1 AEO61483.1 - 0.45 10.1 3.2 3.5 7.3 0.0 3.6 4 0 0 4 4 4 0 Bacteriocin-protection, YdeI or OmpD-Associated Retrotrans_gag PF03732.12 AEO61483.1 - 0.63 10.1 7.8 2.2 8.4 0.0 5.3 7 0 0 7 7 7 0 Retrotransposon gag protein Ima1_N PF09779.4 AEO61484.1 - 2.4e-42 144.5 2.2 4.5e-42 143.6 1.5 1.5 1 0 0 1 1 1 1 Ima1 N-terminal domain RNHCP PF12647.2 AEO61484.1 - 0.09 12.6 2.6 0.11 12.3 0.0 2.3 3 0 0 3 3 3 0 RNHCP domain DZR PF12773.2 AEO61484.1 - 0.12 12.2 5.9 0.44 10.3 0.2 2.6 2 1 0 2 2 2 0 Double zinc ribbon Alg14 PF08660.6 AEO61485.1 - 3.4e-45 154.0 0.0 4.5e-45 153.6 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like AtpR PF12966.2 AEO61485.1 - 0.012 15.7 0.7 0.034 14.3 0.5 1.7 1 0 0 1 1 1 0 N-ATPase, AtpR subunit MRP-S25 PF13741.1 AEO61486.1 - 3.4e-71 239.4 6.4 9.7e-70 234.6 4.4 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S25 Phage_portal PF04860.7 AEO61486.1 - 0.043 12.4 0.0 0.062 11.9 0.0 1.2 1 0 0 1 1 1 0 Phage portal protein PPR_2 PF13041.1 AEO61487.1 - 3.7e-18 65.2 0.0 2.6e-08 33.7 0.1 4.6 3 1 1 4 4 4 3 PPR repeat family PPR_3 PF13812.1 AEO61487.1 - 6e-13 47.9 5.0 0.011 15.9 0.0 6.9 6 0 0 6 6 6 3 Pentatricopeptide repeat domain PPR PF01535.15 AEO61487.1 - 3.2e-11 42.4 9.6 1.8e-05 24.3 0.0 5.6 6 0 0 6 6 6 2 PPR repeat PPR_1 PF12854.2 AEO61487.1 - 2.8e-09 36.2 4.8 0.00055 19.3 0.1 5.4 5 1 0 5 5 5 3 PPR repeat DUF4611 PF15387.1 AEO61487.1 - 0.53 10.4 3.1 1 9.5 2.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) TPR_14 PF13428.1 AEO61487.1 - 0.88 10.3 4.4 1.2e+02 3.7 0.5 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat GSG-1 PF07803.6 AEO61488.1 - 0.01 15.3 1.5 0.04 13.5 0.1 2.3 2 0 0 2 2 2 0 GSG1-like protein DUF373 PF04123.8 AEO61488.1 - 0.29 10.0 3.9 0.21 10.6 1.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF373) DUF2231 PF09990.4 AEO61488.1 - 0.46 10.8 6.6 0.11 12.8 2.2 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) DUF418 PF04235.7 AEO61488.1 - 0.61 9.7 8.7 1.1 8.8 6.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF418) Tetraspannin PF00335.15 AEO61488.1 - 1.1 8.4 8.5 1.5 8.0 5.9 1.3 1 1 0 1 1 1 0 Tetraspanin family Phage_holin_1 PF04531.8 AEO61488.1 - 7.1 6.7 5.9 13 5.9 0.3 2.3 1 1 1 2 2 2 0 Bacteriophage holin DUF202 PF02656.10 AEO61488.1 - 7.3 6.8 13.1 2.1e+02 2.1 9.1 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Thiolase_C PF02803.13 AEO61489.1 - 1.1e-10 41.0 1.5 3.3e-10 39.4 0.2 2.4 2 1 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 AEO61489.1 - 1.1e-07 31.3 1.3 5.8e-06 25.8 0.1 3.0 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 AEO61489.1 - 1.6e-05 24.0 0.4 4.1e-05 22.6 0.0 1.9 3 0 0 3 3 3 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 AEO61489.1 - 0.00094 18.7 0.9 0.0021 17.5 0.1 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 AEO61489.1 - 0.009 15.8 0.4 0.33 10.7 0.0 2.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain SpoVAD PF07451.6 AEO61489.1 - 0.025 13.0 0.4 0.061 11.7 0.1 1.7 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) Aldedh PF00171.17 AEO61491.1 - 3.9e-141 470.5 0.0 4.7e-141 470.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 AEO61491.1 - 2.6e-06 26.4 0.1 0.015 14.0 0.0 2.1 2 0 0 2 2 2 2 Acyl-CoA reductase (LuxC) Ald_Xan_dh_C2 PF02738.13 AEO61492.1 - 1e-194 647.9 0.1 1.4e-194 647.4 0.1 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 AEO61492.1 - 8.5e-49 165.2 0.0 1.6e-48 164.4 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.12 AEO61492.1 - 1.7e-31 108.2 2.0 5.4e-31 106.5 0.1 2.6 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.17 AEO61492.1 - 7.7e-31 106.4 0.0 1.9e-30 105.2 0.0 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.15 AEO61492.1 - 1.1e-28 98.8 0.1 2.3e-28 97.9 0.0 1.5 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.22 AEO61492.1 - 1.8e-07 30.7 1.7 2.9e-07 30.1 0.1 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DUF218 PF02698.12 AEO61492.1 - 0.0088 15.5 0.1 0.053 13.0 0.1 2.1 2 0 0 2 2 2 1 DUF218 domain Sigma70_r3 PF04539.11 AEO61492.1 - 0.13 12.1 0.1 2.1 8.3 0.0 2.6 2 0 0 2 2 2 0 Sigma-70 region 3 SPO22 PF08631.5 AEO61493.1 - 2.7e-74 249.7 4.2 5.8e-74 248.6 0.1 2.4 2 0 0 2 2 2 1 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.1 AEO61493.1 - 2e-05 24.4 3.0 0.16 11.9 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 AEO61493.1 - 0.044 13.6 0.2 21 5.3 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-TRAF PF02176.13 AEO61494.1 - 7.3e-12 45.4 26.8 4.8e-07 30.0 5.2 3.6 1 1 2 3 3 3 3 TRAF-type zinc finger zf-C3HC4_3 PF13920.1 AEO61494.1 - 8.2e-10 38.2 2.8 8.2e-10 38.2 1.9 3.4 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AEO61494.1 - 1.4e-09 37.8 6.4 1.4e-09 37.8 4.4 3.1 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 AEO61494.1 - 2.7e-09 36.7 5.8 2.7e-09 36.7 4.0 3.3 2 1 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.1 AEO61494.1 - 2.1e-07 30.5 4.7 2.1e-07 30.5 3.3 3.2 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 AEO61494.1 - 3.4e-07 29.8 6.8 3.4e-07 29.8 4.7 3.5 3 2 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 AEO61494.1 - 2.7e-06 27.1 8.0 2.7e-06 27.1 5.6 2.7 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 AEO61494.1 - 5.4e-06 26.0 3.7 2.5e-05 23.8 2.5 2.3 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 AEO61494.1 - 0.00013 22.0 1.8 0.00013 22.0 1.2 2.8 2 2 0 2 2 1 1 RING-H2 zinc finger U-box PF04564.10 AEO61494.1 - 0.0065 16.4 0.1 0.015 15.2 0.1 1.6 1 0 0 1 1 1 1 U-box domain zf-DNA_Pol PF08996.5 AEO61494.1 - 0.26 10.6 13.9 1.1 8.5 2.0 2.7 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger zf-RING_4 PF14570.1 AEO61494.1 - 5.3 6.7 15.8 0.18 11.4 0.6 3.9 3 1 0 3 3 3 0 RING/Ubox like zinc-binding domain Ufd2P_core PF10408.4 AEO61495.1 - 2.1e-203 677.0 5.5 2.4e-203 676.8 3.8 1.0 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 AEO61495.1 - 2e-24 85.3 0.7 8.6e-24 83.2 0.5 2.2 1 0 0 1 1 1 1 U-box domain CCDC-167 PF15188.1 AEO61495.1 - 0.099 12.5 0.1 0.099 12.5 0.1 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Epimerase PF01370.16 AEO61496.1 - 4e-20 72.2 0.0 5.6e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 AEO61496.1 - 8.9e-14 50.8 0.0 1.4e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 AEO61496.1 - 2.9e-13 49.3 0.0 3.6e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 AEO61496.1 - 6.9e-12 45.7 2.1 1.8e-11 44.4 1.4 1.8 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 AEO61496.1 - 3.6e-09 36.7 0.4 1.1e-08 35.1 0.2 1.9 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 AEO61496.1 - 1.3e-07 30.8 0.1 1.9e-07 30.3 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 AEO61496.1 - 3.3e-06 26.8 0.1 6.2e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.12 AEO61496.1 - 1.7e-05 25.1 0.0 5.4e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.8 AEO61496.1 - 0.00041 19.6 0.1 0.0089 15.2 0.2 2.3 2 1 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.12 AEO61496.1 - 0.00062 18.7 0.0 0.07 12.0 0.0 2.4 3 0 0 3 3 3 1 RmlD substrate binding domain Methyltransf_26 PF13659.1 AEO61496.1 - 0.031 14.3 1.1 0.22 11.5 0.7 2.4 1 1 0 1 1 1 0 Methyltransferase domain Ala_racemase_N PF01168.15 AEO61496.1 - 0.059 12.9 0.1 1.9 7.9 0.0 2.3 2 0 0 2 2 2 0 Alanine racemase, N-terminal domain ORC6 PF05460.8 AEO61497.1 - 5.7e-35 121.0 7.5 4.7e-34 118.0 1.6 2.6 2 1 0 2 2 2 2 Origin recognition complex subunit 6 (ORC6) Peptidase_M41 PF01434.13 AEO61498.1 - 2.8e-65 219.7 0.7 4.5e-65 219.1 0.5 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 AEO61498.1 - 3.3e-43 147.0 0.0 8.9e-43 145.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 AEO61498.1 - 1.2e-05 25.0 0.0 3.4e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 AEO61498.1 - 2.5e-05 23.2 0.0 4.4e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_17 PF13207.1 AEO61498.1 - 2.6e-05 25.0 0.0 7e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AEO61498.1 - 6.8e-05 22.9 1.6 0.0013 18.7 0.1 3.0 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 AEO61498.1 - 0.00021 21.4 0.1 0.0087 16.2 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 AEO61498.1 - 0.00023 20.5 0.7 0.049 13.0 0.2 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 AEO61498.1 - 0.00078 18.5 0.0 0.0016 17.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 AEO61498.1 - 0.00089 18.9 0.2 0.0039 16.9 0.1 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 AEO61498.1 - 0.001 18.9 0.0 0.0047 16.8 0.0 2.1 1 1 1 2 2 2 1 AAA domain Bac_DnaA PF00308.13 AEO61498.1 - 0.0018 17.9 0.0 0.0032 17.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial dnaA protein IstB_IS21 PF01695.12 AEO61498.1 - 0.002 17.5 0.1 0.0055 16.1 0.1 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 AEO61498.1 - 0.0051 15.9 0.9 0.019 14.0 0.3 2.1 1 1 1 2 2 2 1 Zeta toxin AAA_14 PF13173.1 AEO61498.1 - 0.01 15.7 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 AEO61498.1 - 0.015 14.4 0.2 0.036 13.2 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KaiC PF06745.8 AEO61498.1 - 0.015 14.4 0.0 1.1 8.3 0.0 2.3 2 0 0 2 2 2 0 KaiC AAA_28 PF13521.1 AEO61498.1 - 0.018 15.0 0.0 0.043 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 AEO61498.1 - 0.038 13.9 0.0 0.099 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 AEO61498.1 - 0.039 12.8 0.0 0.076 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.1 AEO61498.1 - 0.065 13.5 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 AEO61498.1 - 0.11 11.6 0.4 0.27 10.4 0.2 1.5 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 AEO61498.1 - 0.17 11.5 0.2 1.1 8.9 0.1 2.1 2 0 0 2 2 2 0 NACHT domain Steroid_dh PF02544.11 AEO61499.1 - 3e-19 69.2 0.2 8.8e-13 48.2 0.3 2.3 2 0 0 2 2 2 2 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 AEO61499.1 - 0.016 14.4 2.2 0.036 13.3 1.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) DUF544 PF04424.8 AEO61500.1 - 8e-14 51.4 0.0 1.2e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF544) DUF3439 PF11921.3 AEO61500.1 - 8.1 6.2 7.7 18 5.0 5.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DnaJ PF00226.26 AEO61501.1 - 1e-24 86.0 0.5 1.9e-24 85.1 0.3 1.5 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.6 AEO61501.1 - 1e-24 86.7 0.1 2.6e-24 85.5 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DUF2416 PF10315.4 AEO61502.1 - 0.0001 22.5 0.1 0.00016 21.9 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2416) Y_phosphatase2 PF03162.8 AEO61503.1 - 9.9e-26 90.0 0.0 1.5e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 AEO61503.1 - 0.012 15.8 0.0 0.11 12.7 0.0 2.1 1 1 1 2 2 2 0 Tyrosine phosphatase family Poxvirus_B22R PF04395.7 AEO61503.1 - 0.069 12.6 0.2 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 Poxvirus B22R protein adh_short PF00106.20 AEO61504.1 - 2.4e-30 105.6 2.7 3.5e-30 105.1 1.9 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO61504.1 - 3.3e-28 99.0 0.3 3.9e-28 98.8 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO61504.1 - 2.1e-12 47.0 2.0 5e-12 45.8 1.4 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 AEO61504.1 - 7.6e-07 28.8 0.2 1e-06 28.3 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TMEM154 PF15102.1 AEO61506.1 - 1.2 8.7 3.6 0.31 10.7 0.1 1.7 2 0 0 2 2 2 0 TMEM154 protein family RabGAP-TBC PF00566.13 AEO61507.1 - 9.3e-47 159.2 0.0 1.7e-46 158.4 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain F-box-like PF12937.2 AEO61508.1 - 6e-07 29.0 0.0 2.3e-06 27.2 0.0 2.0 2 0 0 2 2 2 1 F-box-like MIP-T3 PF10243.4 AEO61509.1 - 0.0041 15.6 16.5 0.0054 15.2 11.4 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Peptidase_S64 PF08192.6 AEO61509.1 - 0.26 9.5 3.5 0.34 9.2 2.4 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF1682 PF07946.9 AEO61509.1 - 1.9 7.2 16.6 3 6.5 11.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Phage_Gp23 PF10669.4 AEO61509.1 - 2 8.5 10.6 4.3 7.4 7.4 1.6 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) DDRGK PF09756.4 AEO61509.1 - 5.1 6.4 22.6 9.1 5.6 15.7 1.3 1 0 0 1 1 1 0 DDRGK domain Ycf1 PF05758.7 AEO61509.1 - 6.4 4.3 7.0 7.7 4.0 4.8 1.0 1 0 0 1 1 1 0 Ycf1 Septin PF00735.13 AEO61510.1 - 2.2e-113 377.9 1.5 2.6e-113 377.7 1.0 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 AEO61510.1 - 6.4e-07 29.3 0.0 1.1e-06 28.5 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 AEO61510.1 - 9.2e-07 28.1 0.0 1.7e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 AEO61510.1 - 1e-05 24.7 0.0 1.8e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 AEO61510.1 - 2.9e-05 23.5 0.7 0.002 17.5 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 AEO61510.1 - 0.00061 19.6 0.6 0.82 9.4 0.2 2.5 1 1 1 2 2 2 2 Dynamin family AAA_23 PF13476.1 AEO61510.1 - 0.00082 19.7 0.5 0.0012 19.2 0.3 1.4 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 AEO61510.1 - 0.0018 17.7 0.0 0.0022 17.4 0.0 1.4 1 1 0 1 1 1 1 AAA-like domain Gtr1_RagA PF04670.7 AEO61510.1 - 0.0057 15.8 0.1 0.036 13.1 0.0 2.0 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 AEO61510.1 - 0.0057 16.7 0.0 0.014 15.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 AEO61510.1 - 0.012 14.5 0.1 0.036 12.9 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein ABC_tran PF00005.22 AEO61510.1 - 0.012 15.9 1.4 0.02 15.2 1.0 1.8 1 1 0 1 1 1 0 ABC transporter NB-ARC PF00931.17 AEO61510.1 - 0.033 13.0 0.0 0.054 12.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Ras PF00071.17 AEO61510.1 - 0.037 13.4 0.1 0.13 11.6 0.0 1.9 2 0 0 2 2 2 0 Ras family AAA_16 PF13191.1 AEO61510.1 - 0.045 13.7 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 AEO61510.1 - 0.049 13.0 0.0 0.097 12.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Miro PF08477.8 AEO61510.1 - 0.13 12.8 0.0 0.42 11.1 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein DUF1542 PF07564.6 AEO61510.1 - 0.15 12.0 0.2 0.37 10.8 0.2 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) Ribosomal_L32p PF01783.18 AEO61511.1 - 1.3e-12 47.6 7.0 1.8e-12 47.2 4.8 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family PolC_DP2 PF03833.8 AEO61511.1 - 0.01 13.5 0.7 0.011 13.4 0.5 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zinc-ribbons_6 PF07191.7 AEO61511.1 - 0.038 13.7 1.1 0.063 13.0 0.8 1.3 1 0 0 1 1 1 0 zinc-ribbons DZR PF12773.2 AEO61511.1 - 0.07 12.9 1.7 0.12 12.2 1.2 1.4 1 0 0 1 1 1 0 Double zinc ribbon TF_Zn_Ribbon PF08271.7 AEO61511.1 - 0.092 12.0 2.6 2.4 7.5 0.1 2.1 1 1 0 1 1 1 0 TFIIB zinc-binding zf-ribbon_3 PF13248.1 AEO61511.1 - 0.33 10.2 5.7 6.4 6.1 1.6 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Atg14 PF10186.4 AEO61511.1 - 1 8.2 4.4 0.22 10.4 0.9 1.4 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1610 PF07754.6 AEO61511.1 - 1.8 8.7 8.4 1.9 8.6 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) zf-FPG_IleRS PF06827.9 AEO61511.1 - 2.2 7.9 5.6 6.4 6.5 3.8 1.7 1 1 0 1 1 1 0 Zinc finger found in FPG and IleRS Zn-ribbon_8 PF09723.5 AEO61511.1 - 2.4 8.2 6.4 2.7 8.0 1.1 2.2 1 1 1 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.1 AEO61511.1 - 2.5 8.5 6.3 2.1e+02 2.4 4.3 2.4 1 1 0 1 1 1 0 Zinc-finger double domain Sgf11 PF08209.6 AEO61511.1 - 2.6 7.4 6.2 2 7.7 0.2 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) WD40 PF00400.27 AEO61512.1 - 5e-22 76.9 13.7 2e-07 30.6 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat PQQ_2 PF13360.1 AEO61512.1 - 0.0002 20.9 0.8 0.0019 17.7 0.5 2.1 1 1 1 2 2 2 1 PQQ-like domain PQQ_3 PF13570.1 AEO61512.1 - 0.00038 20.6 2.9 0.089 13.0 0.1 3.2 3 0 0 3 3 3 2 PQQ-like domain eIF2A PF08662.6 AEO61512.1 - 0.00042 20.0 0.0 0.016 14.9 0.0 2.8 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A Hira PF07569.6 AEO61512.1 - 0.00046 19.4 0.2 0.012 14.8 0.0 2.4 2 0 0 2 2 2 1 TUP1-like enhancer of split Nucleoporin_N PF08801.6 AEO61512.1 - 0.028 13.1 0.1 0.18 10.5 0.0 2.3 2 2 1 3 3 3 0 Nup133 N terminal like Nup160 PF11715.3 AEO61512.1 - 0.055 11.5 0.8 0.43 8.6 0.1 2.0 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Nbas_N PF15492.1 AEO61512.1 - 0.072 12.1 0.0 11 4.9 0.0 3.1 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal DNA_pol_delta_4 PF04081.8 AEO61513.1 - 1.6e-32 112.3 3.0 4.7e-32 110.8 2.1 1.7 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 DUF1737 PF08410.5 AEO61513.1 - 0.048 13.4 0.0 0.089 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1737) Macoilin PF09726.4 AEO61513.1 - 0.77 7.9 4.3 0.97 7.6 3.0 1.1 1 0 0 1 1 1 0 Transmembrane protein OAD_gamma PF04277.8 AEO61513.1 - 1.5 9.2 4.9 3.6 8.0 3.4 1.7 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF2419 PF10343.4 AEO61514.1 - 5.2e-131 436.1 0.0 6.5e-131 435.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) ThiF PF00899.16 AEO61515.1 - 1.6e-41 141.3 0.2 3e-41 140.4 0.1 1.5 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 AEO61515.1 - 1.1e-30 104.9 2.1 1.6e-30 104.4 0.3 2.1 2 0 0 2 2 2 1 Repeat in ubiquitin-activating (UBA) protein UAE_UbL PF14732.1 AEO61515.1 - 1.5e-23 82.6 0.2 3.8e-23 81.3 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.4 AEO61515.1 - 2.2e-19 68.5 0.5 2.2e-19 68.5 0.4 1.9 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.1 AEO61515.1 - 0.00084 19.5 0.1 0.0025 18.0 0.0 1.8 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 AEO61515.1 - 0.0025 17.9 0.0 0.0055 16.7 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase MoeZ_MoeB PF05237.8 AEO61515.1 - 0.069 12.7 0.6 0.84 9.2 0.0 2.5 2 0 0 2 2 2 0 MoeZ/MoeB domain adh_short_C2 PF13561.1 AEO61516.1 - 3.7e-25 89.0 0.1 4.6e-25 88.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 AEO61516.1 - 3.4e-24 85.6 1.4 5.2e-24 85.0 1.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 AEO61516.1 - 7.9e-08 32.0 0.0 3.7e-07 29.8 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 AEO61516.1 - 8.2e-08 32.1 1.9 1.7e-07 31.1 1.1 1.7 1 1 1 2 2 2 1 KR domain Saccharop_dh PF03435.13 AEO61516.1 - 1e-05 24.7 0.1 1.3e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 AEO61516.1 - 0.00064 19.7 2.6 0.0069 16.4 0.5 2.3 2 1 0 2 2 2 1 NADH(P)-binding 3HCDH_N PF02737.13 AEO61516.1 - 0.0013 18.4 0.1 0.0046 16.6 0.0 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 AEO61516.1 - 0.0049 15.7 0.0 0.0065 15.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 AEO61516.1 - 0.0069 16.4 0.4 0.02 15.0 0.2 1.9 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DFP PF04127.10 AEO61516.1 - 0.014 15.0 0.5 0.13 11.9 0.1 2.4 2 1 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein F420_oxidored PF03807.12 AEO61516.1 - 0.014 15.8 1.0 0.17 12.3 0.1 2.5 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.12 AEO61516.1 - 0.015 14.1 0.1 0.11 11.3 0.0 2.2 2 1 0 2 2 2 0 RmlD substrate binding domain THF_DHG_CYH_C PF02882.14 AEO61516.1 - 0.025 13.6 0.0 0.048 12.7 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain YjeF_N PF03853.10 AEO61516.1 - 0.027 14.0 0.2 1.3 8.5 0.0 2.2 2 0 0 2 2 2 0 YjeF-related protein N-terminus Eno-Rase_NADH_b PF12242.3 AEO61516.1 - 0.031 14.0 5.1 0.034 13.9 1.2 2.5 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Glyco_transf_5 PF08323.6 AEO61516.1 - 0.056 12.9 0.0 0.08 12.4 0.0 1.2 1 0 0 1 1 1 0 Starch synthase catalytic domain PAP2 PF01569.16 AEO61517.1 - 2e-18 66.2 4.5 7e-18 64.5 3.1 1.9 1 0 0 1 1 1 1 PAP2 superfamily JmjC PF02373.17 AEO61518.1 - 9.7e-37 125.7 0.5 9.7e-37 125.7 0.4 2.0 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.1 AEO61518.1 - 1.8e-21 76.1 3.8 3.4e-21 75.3 2.7 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 AEO61518.1 - 2.1e-21 75.8 4.0 4.9e-21 74.6 2.8 1.7 1 0 0 1 1 1 1 PHD-like zinc-binding domain JmjN PF02375.12 AEO61518.1 - 7e-08 31.8 4.2 0.0019 17.6 0.0 2.6 2 0 0 2 2 2 2 jmjN domain AA_permease PF00324.16 AEO61520.1 - 3.2e-139 464.3 33.1 3.7e-139 464.1 22.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AEO61520.1 - 3.3e-35 121.4 36.0 4.4e-35 121.0 24.9 1.1 1 0 0 1 1 1 1 Amino acid permease FHA PF00498.21 AEO61522.1 - 8.1e-07 29.0 0.1 1.6e-06 28.1 0.1 1.5 1 0 0 1 1 1 1 FHA domain Pkinase PF00069.20 AEO61522.1 - 0.064 12.3 0.0 0.095 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain IER PF05760.7 AEO61525.1 - 0.23 11.3 4.4 0.26 11.1 3.0 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) YscO PF07321.7 AEO61526.1 - 0.011 15.6 7.9 0.014 15.2 5.5 1.1 1 0 0 1 1 1 0 Type III secretion protein YscO APG6 PF04111.7 AEO61526.1 - 0.014 14.5 1.9 0.016 14.2 1.3 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 OmpH PF03938.9 AEO61526.1 - 0.023 14.6 0.6 0.027 14.4 0.4 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1599 PF07659.6 AEO61526.1 - 0.035 14.1 2.7 2.9 8.0 0.1 2.2 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1599) Uds1 PF15456.1 AEO61526.1 - 0.049 13.6 4.1 0.078 12.9 2.9 1.3 1 0 0 1 1 1 0 Up-regulated During Septation DUF1664 PF07889.7 AEO61526.1 - 0.079 12.7 0.3 0.11 12.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Fzo_mitofusin PF04799.8 AEO61526.1 - 0.11 11.8 1.3 0.15 11.4 0.9 1.1 1 0 0 1 1 1 0 fzo-like conserved region V_ATPase_I PF01496.14 AEO61526.1 - 0.2 9.5 0.2 0.22 9.3 0.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF724 PF05266.9 AEO61526.1 - 0.22 11.0 3.0 0.28 10.7 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) FlgN PF05130.7 AEO61526.1 - 0.26 11.5 8.0 0.51 10.5 5.6 1.4 1 1 0 1 1 1 0 FlgN protein CALCOCO1 PF07888.6 AEO61526.1 - 0.3 9.3 8.1 0.35 9.1 5.6 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2852 PF11014.3 AEO61526.1 - 2.4 8.1 7.0 5.8 6.8 4.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2852) zf-RING_2 PF13639.1 AEO61527.1 - 4.3e-15 55.2 17.3 5.8e-15 54.8 3.5 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 AEO61527.1 - 7.5e-10 38.3 12.3 1.4e-07 31.0 2.6 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 AEO61527.1 - 2.8e-08 33.6 14.9 2.9e-07 30.4 3.2 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 AEO61527.1 - 3e-07 30.0 12.1 4e-06 26.3 1.8 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 AEO61527.1 - 5.1e-07 29.7 2.6 5.1e-07 29.7 1.8 2.6 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 AEO61527.1 - 6.4e-07 28.9 11.5 1e-05 25.1 1.8 2.4 2 0 0 2 2 2 2 zinc-RING finger domain zf-Apc11 PF12861.2 AEO61527.1 - 0.0005 19.8 1.2 0.0005 19.8 0.8 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Pex14_N PF04695.8 AEO61527.1 - 0.0078 16.2 15.1 0.0078 16.2 10.5 2.3 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region SAGA-Tad1 PF12767.2 AEO61527.1 - 0.032 13.8 11.9 0.011 15.3 6.1 1.7 2 1 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit FANCL_C PF11793.3 AEO61527.1 - 0.15 12.0 7.7 1.5 8.8 2.2 3.3 2 1 0 2 2 2 0 FANCL C-terminal domain Cytochrom_B_N PF00033.14 AEO61527.1 - 0.16 11.3 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB zf-RING_4 PF14570.1 AEO61527.1 - 0.16 11.5 12.7 0.24 11.0 2.0 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 AEO61527.1 - 0.55 9.8 8.6 0.062 12.8 2.0 2.4 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 Hid1 PF12722.2 AEO61527.1 - 0.9 7.1 4.1 1.3 6.5 2.9 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein zf-RING_UBOX PF13445.1 AEO61527.1 - 0.95 9.2 4.9 1.9 8.2 0.4 3.4 2 1 1 3 3 3 0 RING-type zinc-finger DUF4175 PF13779.1 AEO61527.1 - 1.2 6.7 22.6 1.7 6.2 15.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) zf-RING_6 PF14835.1 AEO61527.1 - 2.7 7.8 9.0 0.58 9.9 1.3 2.3 2 0 0 2 2 2 0 zf-RING of BARD1-type protein HypA PF01155.14 AEO61527.1 - 3.3 7.4 11.2 0.096 12.3 2.1 2.2 2 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Prok-RING_1 PF14446.1 AEO61527.1 - 3.7 7.3 12.2 17 5.2 3.7 2.8 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 RINGv PF12906.2 AEO61527.1 - 9.9 6.3 12.8 3.6 7.7 1.5 2.7 2 1 0 2 2 2 0 RING-variant domain Fungal_trans PF04082.13 AEO61528.1 - 1.5e-11 43.6 0.0 2.4e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO61528.1 - 1.7e-08 34.2 11.0 4.9e-08 32.7 7.6 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APH PF01636.18 AEO61528.1 - 4.6e-05 23.2 2.1 0.00023 20.9 1.4 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Dicty_REP PF05086.7 AEO61528.1 - 0.89 7.2 4.7 1.2 6.8 3.3 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Dickkopf_N PF04706.7 AEO61528.1 - 2.2 8.4 10.7 4.9 7.4 7.4 1.5 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region SSP160 PF06933.6 AEO61528.1 - 3.4 5.5 14.7 5.1 4.9 10.2 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 MFS_1 PF07690.11 AEO61530.1 - 2.3e-31 108.8 76.4 1.1e-24 86.8 33.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 AEO61530.1 - 6.1e-07 29.1 7.3 0.00076 19.2 0.9 3.7 3 0 0 3 3 3 2 MFS_1 like family MFS_2 PF13347.1 AEO61530.1 - 0.05 11.9 41.1 0.51 8.6 15.4 3.6 1 1 3 4 4 4 0 MFS/sugar transport protein APH PF01636.18 AEO61531.1 - 6.4e-22 78.4 0.2 2e-21 76.8 0.1 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 AEO61531.1 - 0.12 11.3 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Fructosamine kinase CysG_dimeriser PF10414.4 AEO61532.1 - 0.0013 18.2 0.2 0.0037 16.7 0.1 1.8 1 0 0 1 1 1 1 Sirohaem synthase dimerisation region p450 PF00067.17 AEO61533.1 - 0.011 14.3 0.0 0.042 12.3 0.0 1.9 3 0 0 3 3 3 0 Cytochrome P450 DUF3716 PF12511.3 AEO61535.1 - 2.6e-16 58.9 2.8 4.2e-16 58.2 2.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) SNARE PF05739.14 AEO61536.1 - 3.9e-09 36.0 3.8 7.7e-09 35.1 2.7 1.5 1 0 0 1 1 1 1 SNARE domain CorA PF01544.13 AEO61536.1 - 0.031 13.3 0.0 0.031 13.3 0.0 2.6 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein WXG100 PF06013.7 AEO61536.1 - 0.045 13.7 0.1 0.045 13.7 0.1 3.3 2 2 1 3 3 3 0 Proteins of 100 residues with WXG Rifin_STEVOR PF02009.11 AEO61536.1 - 0.066 12.8 0.1 0.1 12.1 0.1 1.3 1 0 0 1 1 1 0 Rifin/stevor family Syntaxin PF00804.20 AEO61536.1 - 0.12 12.5 3.7 5 7.3 0.1 2.3 2 0 0 2 2 2 0 Syntaxin Mito_fiss_reg PF05308.6 AEO61536.1 - 0.27 10.5 4.1 0.4 10.0 2.8 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator DivIC PF04977.10 AEO61536.1 - 2.8 7.5 5.4 1.7 8.2 1.4 2.3 2 0 0 2 2 2 0 Septum formation initiator WD40 PF00400.27 AEO61537.1 - 1.9e-09 37.0 4.0 5.1e-05 23.0 0.0 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat PPTA PF01239.17 AEO61538.1 - 4.4e-30 101.7 9.7 9.1e-08 31.1 0.4 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat Sporozoite_P67 PF05642.6 AEO61538.1 - 0.92 7.2 6.6 1.2 6.9 4.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Med3 PF11593.3 AEO61538.1 - 4.3 6.4 13.3 5.9 6.0 9.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF1908 PF08926.6 AEO61538.1 - 5.8 5.5 6.8 9.2 4.9 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) ATP_bind_3 PF01171.15 AEO61539.1 - 1.2e-32 112.8 0.0 1.7e-21 76.5 0.0 2.3 2 0 0 2 2 2 2 PP-loop family Mito_carr PF00153.22 AEO61540.1 - 2e-47 158.8 5.4 1.1e-17 63.5 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF3337 PF11816.3 AEO61541.1 - 2e-96 323.2 0.0 6.1e-94 315.1 0.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3337) WD40 PF00400.27 AEO61541.1 - 8.3e-25 85.7 10.8 2.7e-07 30.2 0.0 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 AEO61541.1 - 0.0031 16.3 0.1 0.83 8.3 0.0 3.0 2 1 0 3 3 3 2 Nup133 N terminal like Nup160 PF11715.3 AEO61541.1 - 0.016 13.3 0.1 0.03 12.4 0.1 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 DUF4098 PF13345.1 AEO61543.1 - 0.0091 15.9 4.1 0.56 10.1 0.1 4.4 5 0 0 5 5 5 1 Domain of unknown function (DUF4098) Sensor PF13796.1 AEO61543.1 - 0.036 13.6 0.1 0.079 12.5 0.1 1.5 1 0 0 1 1 1 0 Putative sensor Mito_carr PF00153.22 AEO61544.1 - 1.3e-67 223.5 5.4 7.8e-26 89.6 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 AEO61545.1 - 3.9e-06 26.9 0.0 5.5e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 AEO61545.1 - 0.00028 19.9 0.0 0.023 13.9 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 AEO61545.1 - 0.0022 17.6 0.0 0.47 10.4 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_9 PF14658.1 AEO61545.1 - 0.03 14.2 0.0 0.061 13.2 0.0 1.5 2 0 0 2 2 2 0 EF-hand domain EF-hand_8 PF13833.1 AEO61545.1 - 0.032 13.8 0.0 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 EF-hand domain pair Cyclin_N PF00134.18 AEO61546.1 - 1.4e-07 31.1 0.0 1.4e-07 31.1 0.0 2.5 3 0 0 3 3 3 1 Cyclin, N-terminal domain CDK2AP PF09806.4 AEO61546.1 - 0.0072 16.5 17.1 0.047 13.9 4.4 2.1 2 0 0 2 2 2 2 Cyclin-dependent kinase 2-associated protein TFIIB PF00382.14 AEO61546.1 - 0.033 14.0 0.1 0.1 12.4 0.0 1.8 1 0 0 1 1 1 0 Transcription factor TFIIB repeat HemX PF04375.9 AEO61546.1 - 1.3 7.5 14.7 1.8 7.0 10.2 1.2 1 0 0 1 1 1 0 HemX BTB PF00651.26 AEO61548.1 - 0.00063 19.7 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF4452 PF14618.1 AEO61549.1 - 6.1e-76 253.8 11.1 7.7e-76 253.5 7.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) DUF4228 PF14009.1 AEO61550.1 - 0.018 15.1 0.6 0.018 15.1 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) Luteo_Vpg PF01659.11 AEO61550.1 - 0.066 12.9 2.0 0.1 12.2 1.4 1.3 1 0 0 1 1 1 0 Luteovirus putative VPg genome linked protein JmjC PF02373.17 AEO61551.1 - 2.7e-10 40.4 0.2 7.9e-10 38.9 0.1 1.9 1 1 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.4 AEO61551.1 - 3.7e-07 30.2 7.6 3.7e-07 30.2 5.3 3.2 3 0 0 3 3 3 1 Zinc-finger domain of monoamine-oxidase A repressor R1 HNH_5 PF14279.1 AEO61551.1 - 0.051 13.5 3.7 0.14 12.2 2.6 1.7 1 0 0 1 1 1 0 HNH endonuclease Cupin_2 PF07883.6 AEO61551.1 - 0.056 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Cupin domain UbiA PF01040.13 AEO61552.1 - 3.2e-34 118.3 22.3 4.5e-34 117.8 15.5 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family T2SM PF04612.7 AEO61553.1 - 0.1 12.3 2.0 0.2 11.4 1.4 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M ADK PF00406.17 AEO61554.1 - 1.6e-60 203.3 0.0 2e-60 203.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 AEO61554.1 - 5.4e-15 54.7 0.1 1.7e-14 53.1 0.0 1.9 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_17 PF13207.1 AEO61554.1 - 2.1e-07 31.8 0.1 3.7e-07 30.9 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AEO61554.1 - 0.00012 21.9 0.0 0.00024 20.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 AEO61554.1 - 0.0015 17.6 0.0 0.0023 17.0 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 AEO61554.1 - 0.002 18.4 0.0 0.0052 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 AEO61554.1 - 0.13 11.6 0.0 1 8.7 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase HOOK PF05622.7 AEO61555.1 - 0.00015 19.7 0.5 0.00019 19.4 0.3 1.1 1 0 0 1 1 1 1 HOOK protein TMF_DNA_bd PF12329.3 AEO61555.1 - 0.15 11.8 4.3 4.1 7.2 1.2 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Rootletin PF15035.1 AEO61555.1 - 0.32 10.9 6.0 1.7 8.5 0.6 2.1 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Chalcone PF02431.10 AEO61556.1 - 0.022 14.1 1.1 0.033 13.5 0.8 1.2 1 0 0 1 1 1 0 Chalcone-flavanone isomerase Spc7 PF08317.6 AEO61556.1 - 0.7 8.4 14.0 1.1 7.9 9.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.4 AEO61556.1 - 1.4 7.7 20.8 0.05 12.5 3.2 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 TMPIT PF07851.8 AEO61556.1 - 2.1 7.3 3.9 1.2 8.1 1.1 1.7 1 1 1 2 2 2 0 TMPIT-like protein DUF4200 PF13863.1 AEO61556.1 - 2.2 8.2 23.3 1.8 8.4 2.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Bap31 PF05529.7 AEO61556.1 - 2.6 7.4 16.0 0.55 9.6 2.7 2.4 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like DUF572 PF04502.8 AEO61556.1 - 3.6 6.7 14.9 4.8 6.2 10.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) V_ATPase_I PF01496.14 AEO61556.1 - 3.7 5.2 5.3 4.4 5.0 3.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GAS PF13851.1 AEO61556.1 - 4.3 6.4 16.2 0.26 10.4 6.9 1.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding PcfJ PF14284.1 AEO61556.1 - 4.3 6.7 6.9 5.4 6.4 0.1 2.3 1 1 0 2 2 2 0 PcfJ-like protein AAA_13 PF13166.1 AEO61556.1 - 5.5 5.3 9.5 7.3 4.9 6.6 1.1 1 0 0 1 1 1 0 AAA domain Inhibitor_I9 PF05922.11 AEO61557.1 - 0.012 16.1 0.2 0.019 15.5 0.1 1.5 1 1 0 1 1 1 0 Peptidase inhibitor I9 DUF3186 PF11382.3 AEO61557.1 - 0.012 14.7 0.2 0.014 14.5 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) MitMem_reg PF13012.1 AEO61558.1 - 4.2e-39 133.1 0.2 9.5e-39 132.0 0.0 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 AEO61558.1 - 5.7e-29 100.1 0.0 1.2e-28 99.0 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Mito_fiss_reg PF05308.6 AEO61559.1 - 0.13 11.6 10.2 0.18 11.1 7.1 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Coprogen_oxidas PF01218.13 AEO61560.1 - 1.4e-134 447.2 0.1 1.7e-134 447.0 0.0 1.1 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Atg8 PF02991.11 AEO61561.1 - 2.6e-51 171.8 0.2 3.1e-51 171.6 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 AEO61561.1 - 2.7e-06 27.4 0.0 3.3e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 LIM_bind PF01803.11 AEO61562.1 - 1e-78 263.7 0.0 1e-78 263.7 0.0 6.0 4 1 2 6 6 6 1 LIM-domain binding protein HbrB PF08539.6 AEO61563.1 - 8e-60 201.2 0.1 1.5e-59 200.3 0.0 1.5 2 0 0 2 2 2 1 HbrB-like Gon7 PF08738.5 AEO61564.1 - 3.7e-18 65.4 4.9 1.1e-17 63.8 3.4 1.6 1 1 0 1 1 1 1 Gon7 family GCOM2 PF15328.1 AEO61564.1 - 0.014 15.1 3.1 0.017 14.8 2.2 1.1 1 0 0 1 1 1 0 Putative GRINL1B complex locus protein 2 ImcF-related_N PF14331.1 AEO61564.1 - 0.062 12.2 0.1 0.075 11.9 0.1 1.1 1 0 0 1 1 1 0 ImcF-related N-terminal domain DnaB_bind PF10410.4 AEO61564.1 - 0.083 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 DnaB-helicase binding domain of primase Vps39_1 PF10366.4 AEO61565.1 - 4.5e-33 113.4 0.0 5.3e-32 110.0 0.0 2.8 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 AEO61565.1 - 1.5e-29 102.3 0.0 3.6e-29 101.1 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 AEO61565.1 - 7.5e-19 68.1 0.0 2.4e-18 66.5 0.0 1.7 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.15 AEO61565.1 - 2.6e-06 27.0 0.4 0.002 17.7 0.0 3.1 3 0 0 3 3 3 2 Region in Clathrin and VPS TPR_19 PF14559.1 AEO61565.1 - 0.011 16.0 0.6 2.2 8.6 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2175 PF09943.4 AEO61565.1 - 0.031 14.3 0.0 0.51 10.4 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) TPR_1 PF00515.23 AEO61565.1 - 0.13 11.9 4.9 2.1 8.0 0.3 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat SPX PF03105.14 AEO61566.1 - 3e-50 171.5 0.2 7.5e-50 170.2 0.1 1.6 1 1 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 AEO61566.1 - 9.5e-35 120.3 38.4 1.5e-34 119.7 26.6 1.4 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 AEO61566.1 - 2.2e-12 46.2 44.1 3.2e-11 42.4 17.0 2.8 2 1 1 3 3 3 2 Citrate transporter DUF1631 PF07793.6 AEO61566.1 - 0.13 10.3 0.0 0.18 9.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) DUF4050 PF13259.1 AEO61567.1 - 8e-35 119.4 0.0 8e-35 119.4 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF4050) Pex14_N PF04695.8 AEO61568.1 - 4.3e-22 78.6 0.5 4.3e-22 78.6 0.4 2.8 2 1 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region IncA PF04156.9 AEO61568.1 - 0.025 14.1 0.4 0.025 14.1 0.3 1.8 2 1 0 2 2 2 0 IncA protein DASH_Dad4 PF08650.5 AEO61568.1 - 0.072 13.0 0.1 0.29 11.0 0.0 2.1 2 0 0 2 2 2 0 DASH complex subunit Dad4 PAPA-1 PF04795.7 AEO61569.1 - 3.3e-26 91.7 3.7 3.3e-26 91.7 2.5 3.8 4 0 0 4 4 4 1 PAPA-1-like conserved region VPS11_C PF12451.3 AEO61570.1 - 0.39 10.6 4.6 0.4 10.5 1.0 2.6 1 1 1 2 2 2 0 Vacuolar protein sorting protein 11 C terminal Eapp_C PF10238.4 AEO61570.1 - 2.6 7.9 8.0 10 6.0 5.6 2.0 1 1 0 1 1 1 0 E2F-associated phosphoprotein Gp_dh_C PF02800.15 AEO61571.1 - 1.6e-76 255.0 0.0 2.4e-76 254.5 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 AEO61571.1 - 9.3e-60 200.9 0.1 1.4e-59 200.4 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 AEO61571.1 - 0.0038 17.1 0.1 0.014 15.3 0.0 2.0 3 0 0 3 3 3 1 Dihydrodipicolinate reductase, N-terminus Hist_deacetyl PF00850.14 AEO61573.1 - 6.4e-88 295.0 0.0 9.6e-88 294.4 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 AEO61573.1 - 3.7e-45 153.5 0.1 6.3e-45 152.7 0.1 1.3 1 0 0 1 1 1 1 Arb2 domain Brix PF04427.13 AEO61574.1 - 5.4e-39 133.8 0.0 7.6e-39 133.3 0.0 1.2 1 0 0 1 1 1 1 Brix domain Phage_Nu1 PF07471.7 AEO61574.1 - 0.085 12.3 0.1 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Phage DNA packaging protein Nu1 Ras PF00071.17 AEO61575.1 - 2e-62 209.3 0.1 3.2e-62 208.7 0.1 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AEO61575.1 - 1.8e-21 76.8 0.1 2.6e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AEO61575.1 - 4.4e-12 45.5 0.0 5.5e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 AEO61575.1 - 2.1e-07 30.8 0.0 3.1e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 AEO61575.1 - 5.5e-05 22.6 0.0 0.00019 20.9 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 AEO61575.1 - 0.00028 21.0 0.0 0.0007 19.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 AEO61575.1 - 0.0014 17.8 0.2 0.0034 16.5 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Gtr1_RagA PF04670.7 AEO61575.1 - 0.0034 16.5 0.1 0.0044 16.1 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SpoIIID PF12116.3 AEO61575.1 - 0.0047 16.8 0.0 0.059 13.3 0.0 2.1 2 0 0 2 2 2 1 Stage III sporulation protein D AAA_15 PF13175.1 AEO61575.1 - 0.006 15.6 0.3 0.0073 15.3 0.2 1.2 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.22 AEO61575.1 - 0.017 15.4 0.1 0.028 14.7 0.1 1.4 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.1 AEO61575.1 - 0.022 14.6 0.0 0.046 13.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 AEO61575.1 - 0.024 13.8 0.1 0.093 12.0 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_24 PF13479.1 AEO61575.1 - 0.027 14.0 0.1 0.058 12.9 0.1 1.6 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 AEO61575.1 - 0.043 13.3 0.0 0.088 12.2 0.0 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 AEO61575.1 - 0.061 13.2 0.1 0.085 12.8 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.5 AEO61575.1 - 0.077 12.2 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.1 AEO61575.1 - 0.1 12.1 0.0 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 AEO61575.1 - 0.11 12.1 0.0 0.25 11.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Chromo PF00385.19 AEO61576.1 - 1.1e-11 44.2 0.9 3.6e-11 42.5 0.6 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF4066 PF13278.1 AEO61577.1 - 2.3e-25 88.8 0.0 3.1e-25 88.3 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 AEO61577.1 - 1.3e-12 47.3 0.0 1.9e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family cobW PF02492.14 AEO61578.1 - 9.6e-35 119.6 0.0 1.2e-34 119.3 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 AEO61578.1 - 1.2e-06 27.5 1.4 4.8e-06 25.5 1.0 1.7 1 1 0 1 1 1 1 ArgK protein AAA_17 PF13207.1 AEO61578.1 - 0.005 17.6 0.0 0.008 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 AEO61578.1 - 0.009 15.9 0.0 0.03 14.2 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.1 AEO61578.1 - 0.018 15.3 0.0 0.034 14.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 AEO61578.1 - 0.027 14.1 0.0 0.053 13.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TIP49 PF06068.8 AEO61578.1 - 0.051 12.2 0.0 0.072 11.8 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus IstB_IS21 PF01695.12 AEO61578.1 - 0.072 12.5 0.0 0.18 11.2 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein PRK PF00485.13 AEO61578.1 - 0.13 11.7 0.1 0.25 10.9 0.0 1.5 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_21 PF13304.1 AEO61578.1 - 0.15 12.0 0.0 0.71 9.7 0.0 1.9 2 1 0 2 2 2 0 AAA domain DUF663 PF04950.7 AEO61579.1 - 1.9e-102 342.2 0.0 3.2e-102 341.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 AEO61579.1 - 2.5e-20 71.8 0.0 5e-20 70.8 0.0 1.5 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 AEO61579.1 - 0.12 11.7 0.0 0.4 10.0 0.0 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain BING4CT PF08149.6 AEO61580.1 - 2.7e-40 135.7 0.0 9.4e-38 127.5 0.0 3.1 3 0 0 3 3 3 2 BING4CT (NUC141) domain WD40 PF00400.27 AEO61580.1 - 9e-08 31.7 0.0 1.7e-05 24.4 0.0 3.9 5 0 0 5 5 5 1 WD domain, G-beta repeat PQQ_2 PF13360.1 AEO61580.1 - 0.02 14.3 0.0 0.05 13.0 0.0 1.7 1 1 0 1 1 1 0 PQQ-like domain PTH2 PF01981.11 AEO61581.1 - 9.8e-48 160.6 0.2 1.3e-47 160.2 0.2 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 SART-1 PF03343.8 AEO61582.1 - 2.2e-172 574.6 52.0 2.5e-172 574.4 36.1 1.0 1 0 0 1 1 1 1 SART-1 family Glyco_hydro_15 PF00723.16 AEO61583.1 - 1.8e-100 336.6 0.0 2.3e-100 336.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 AEO61583.1 - 1.5e-32 111.0 0.8 4.5e-32 109.5 0.6 1.9 1 0 0 1 1 1 1 Starch binding domain AAA_17 PF13207.1 AEO61584.1 - 6e-06 27.0 0.0 1.8e-05 25.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 AEO61584.1 - 0.00024 21.3 0.0 0.0019 18.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain CPT PF07931.7 AEO61584.1 - 0.0013 18.3 0.0 0.0022 17.6 0.0 1.3 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_28 PF13521.1 AEO61584.1 - 0.014 15.3 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain PRK PF00485.13 AEO61584.1 - 0.049 13.1 0.0 0.1 12.1 0.0 1.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_22 PF13401.1 AEO61584.1 - 0.066 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF605 PF04652.11 AEO61584.1 - 1.7 7.9 8.3 2.1 7.6 5.8 1.1 1 0 0 1 1 1 0 Vta1 like NMN_transporter PF04973.7 AEO61585.1 - 0.033 13.6 0.0 0.038 13.4 0.0 1.0 1 0 0 1 1 1 0 Nicotinamide mononucleotide transporter DUF3328 PF11807.3 AEO61585.1 - 0.035 13.7 0.0 0.036 13.7 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) DUF4234 PF14018.1 AEO61585.1 - 0.043 13.5 0.2 0.053 13.2 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) C2 PF00168.25 AEO61586.1 - 7.2e-21 73.8 0.0 2.7e-14 52.7 0.0 2.4 2 0 0 2 2 2 2 C2 domain PNP_UDP_1 PF01048.15 AEO61587.1 - 4.2e-12 45.5 0.1 9.1e-12 44.4 0.1 1.6 1 1 0 1 1 1 1 Phosphorylase superfamily IMS PF00817.15 AEO61589.1 - 4.6e-18 65.4 0.0 7.4e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 AEO61589.1 - 5.1e-06 26.4 0.0 1.3e-05 25.1 0.0 1.7 1 1 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 AEO61589.1 - 0.00037 20.3 0.0 0.00092 19.1 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif PBP1_TM PF14812.1 AEO61589.1 - 0.026 14.8 1.1 0.026 14.8 0.8 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4611 PF15387.1 AEO61589.1 - 0.04 14.0 3.4 0.068 13.3 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) HLH PF00010.21 AEO61590.1 - 2.6e-05 23.7 0.0 5.9e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF485 PF04341.7 AEO61592.1 - 1 9.0 4.4 1.6 8.5 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function, DUF485 COesterase PF00135.23 AEO61593.1 - 3e-85 286.9 0.0 4e-85 286.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 AEO61593.1 - 4.5e-06 26.4 0.0 1.3e-05 24.8 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Mucin PF01456.12 AEO61593.1 - 3 7.6 27.8 5.5 6.7 19.3 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DASH_Dad2 PF08654.5 AEO61595.1 - 8e-34 115.7 0.8 1.1e-33 115.3 0.6 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad2 Seryl_tRNA_N PF02403.17 AEO61595.1 - 0.017 15.1 0.5 0.026 14.5 0.2 1.5 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Shugoshin_N PF07558.6 AEO61596.1 - 2.2e-15 56.0 6.2 4.9e-15 54.9 4.3 1.6 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.6 AEO61596.1 - 4.3e-10 38.8 5.7 4.3e-10 38.8 3.9 4.6 5 0 0 5 5 5 1 Shugoshin C terminus AKNA PF12443.3 AEO61596.1 - 0.029 14.3 0.9 0.029 14.3 0.6 2.3 2 0 0 2 2 2 0 AT-hook-containing transcription factor BCAS2 PF05700.6 AEO61596.1 - 0.092 12.1 2.6 0.12 11.7 0.7 1.9 2 0 0 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) HALZ PF02183.13 AEO61596.1 - 0.14 11.9 2.7 0.37 10.5 1.9 1.8 1 0 0 1 1 1 0 Homeobox associated leucine zipper Mod_r PF07200.8 AEO61596.1 - 2.5 8.0 8.5 1.9 8.3 2.9 2.7 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Metallophos_2 PF12850.2 AEO61597.1 - 3.1e-11 43.3 0.0 3.8e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 AEO61597.1 - 0.044 13.1 0.0 0.083 12.2 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase Aminotran_5 PF00266.14 AEO61598.1 - 2.3e-28 99.0 0.0 2.9e-28 98.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 AEO61598.1 - 0.0012 17.9 0.0 0.0022 17.0 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II CRM1_C PF08767.6 AEO61599.1 - 1.3e-130 435.0 1.9 1.3e-130 435.0 1.3 3.4 4 1 0 4 4 4 1 CRM1 C terminal Xpo1 PF08389.7 AEO61599.1 - 1.9e-41 141.3 6.4 1.9e-41 141.3 4.4 3.7 5 1 0 5 5 5 1 Exportin 1-like protein IBN_N PF03810.14 AEO61599.1 - 7.4e-13 48.2 0.1 2.6e-12 46.4 0.1 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3385 PF11865.3 AEO61599.1 - 0.035 14.0 2.8 0.15 11.9 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF3385) Vac14_Fab1_bd PF12755.2 AEO61599.1 - 0.04 14.3 2.0 1.1 9.6 0.0 4.1 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region HECT PF00632.20 AEO61600.1 - 3.3e-66 223.6 0.0 4.7e-66 223.1 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SKG6 PF08693.5 AEO61601.1 - 1.2e-11 43.6 0.7 3.4e-11 42.2 0.5 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.1 AEO61601.1 - 7.4e-06 25.7 0.0 7.4e-06 25.7 0.0 2.3 2 0 0 2 2 2 1 TMEM154 protein family DUF4448 PF14610.1 AEO61601.1 - 0.00082 18.9 1.5 0.0015 18.0 0.0 1.9 1 1 0 2 2 2 1 Protein of unknown function (DUF4448) Herpes_gE PF02480.11 AEO61601.1 - 0.0013 17.1 0.3 0.0013 17.1 0.2 2.0 1 1 2 3 3 3 1 Alphaherpesvirus glycoprotein E DUF1191 PF06697.7 AEO61601.1 - 0.057 12.2 0.0 0.078 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) CcmD PF04995.9 AEO61601.1 - 0.078 12.7 1.8 0.14 11.9 1.2 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Plasmodium_Vir PF05795.6 AEO61601.1 - 1.8 7.7 7.3 6 5.9 5.1 1.8 1 1 0 1 1 1 0 Plasmodium vivax Vir protein TFIIA PF03153.8 AEO61601.1 - 7.3 6.3 10.0 9.8 5.9 7.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cpn60_TCP1 PF00118.19 AEO61602.1 - 3.2e-164 547.1 0.3 3.7e-164 546.9 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1168 PF06658.7 AEO61603.1 - 2.3e-38 130.9 19.4 3.1e-38 130.4 13.5 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1168) RNA_polI_A34 PF08208.6 AEO61603.1 - 0.0036 17.0 7.6 0.0062 16.2 5.3 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 MIP-T3 PF10243.4 AEO61603.1 - 0.0036 15.8 7.0 0.004 15.6 4.8 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 eIF-3_zeta PF05091.7 AEO61603.1 - 0.19 10.2 2.1 0.23 10.0 1.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RNase_H2-Ydr279 PF09468.5 AEO61603.1 - 5.4 6.1 8.5 7.6 5.6 5.9 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF3987 PF13148.1 AEO61603.1 - 9.6 4.6 10.4 14 4.1 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) His_Phos_1 PF00300.17 AEO61604.1 - 5.5e-32 111.0 0.0 1e-31 110.1 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 AEO61604.1 - 7.3e-05 22.2 0.0 0.00011 21.6 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Ecl1 PF12855.2 AEO61606.1 - 1.5e-07 30.6 1.8 3e-07 29.6 1.3 1.5 1 0 0 1 1 1 1 Life-span regulatory factor zf-MYND PF01753.13 AEO61606.1 - 0.019 14.8 1.6 0.047 13.5 1.1 1.6 1 0 0 1 1 1 0 MYND finger Exo_endo_phos PF03372.18 AEO61608.1 - 5.2e-11 42.9 0.0 6e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zinc_ribbon_6 PF14599.1 AEO61609.1 - 4.7e-25 87.1 2.7 4.7e-25 87.1 1.9 4.0 3 1 1 4 4 4 1 Zinc-ribbon zf-CHY PF05495.7 AEO61609.1 - 1.2e-15 57.4 23.2 1.2e-15 57.4 16.1 4.6 4 2 1 5 5 5 1 CHY zinc finger zf-RING_2 PF13639.1 AEO61609.1 - 7.6e-08 32.0 5.8 7.6e-08 32.0 4.0 4.4 2 1 2 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.1 AEO61609.1 - 3.9e-07 29.9 6.4 3.9e-07 29.9 4.4 5.4 3 1 2 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO61609.1 - 0.00013 21.6 7.2 0.00013 21.6 5.0 6.1 4 2 1 5 5 5 1 zinc-RING finger domain Suf PF05843.9 AEO61609.1 - 0.13 12.0 4.9 0.22 11.2 3.4 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spt20 PF12090.3 AEO61609.1 - 0.76 9.1 8.2 1.4 8.2 5.7 1.3 1 0 0 1 1 1 0 Spt20 family DivIC PF04977.10 AEO61609.1 - 0.96 8.9 8.0 1.7 8.1 5.5 1.4 1 0 0 1 1 1 0 Septum formation initiator Med3 PF11593.3 AEO61609.1 - 4.8 6.3 21.8 8.5 5.4 0.7 2.5 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal MOZART1 PF12554.3 AEO61610.1 - 1.3e-25 88.5 1.0 1.6e-25 88.3 0.7 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated MOZART2 PF12926.2 AEO61610.1 - 0.013 15.0 0.3 0.016 14.8 0.2 1.1 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated Spindle_Spc25 PF08234.7 AEO61611.1 - 1.1e-22 79.7 0.3 3.1e-22 78.3 0.0 1.9 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 Joubert PF15392.1 AEO61611.1 - 0.05 12.8 6.2 0.07 12.3 4.3 1.1 1 0 0 1 1 1 0 Joubert syndrome-associated Atg14 PF10186.4 AEO61611.1 - 0.17 10.8 10.5 0.29 10.0 7.3 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF342 PF03961.8 AEO61611.1 - 0.36 9.1 3.8 0.54 8.5 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) FUSC PF04632.7 AEO61611.1 - 0.69 8.2 9.8 0.89 7.9 6.8 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family ADIP PF11559.3 AEO61611.1 - 0.87 9.4 20.5 0.83 9.5 7.1 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Mnd1 PF03962.10 AEO61611.1 - 4.7 6.8 14.8 4.7 6.8 3.8 2.3 1 1 1 2 2 2 0 Mnd1 family Rrn6 PF10214.4 AEO61612.1 - 6e-72 242.9 19.4 4.7e-60 203.5 0.0 3.4 4 0 0 4 4 4 3 RNA polymerase I-specific transcription-initiation factor PITH PF06201.8 AEO61613.1 - 4.3e-48 162.9 0.0 5.1e-48 162.6 0.0 1.1 1 0 0 1 1 1 1 PITH domain DUF814 PF05670.8 AEO61614.1 - 1.2e-19 69.9 0.0 2.2e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Ribosomal_L3 PF00297.17 AEO61615.1 - 1.2e-33 116.6 2.3 1.9e-33 116.0 1.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L3 Coa1 PF08695.5 AEO61616.1 - 3e-40 136.3 0.0 3.7e-40 136.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 DUF2339 PF10101.4 AEO61617.1 - 0.05 11.8 7.0 0.094 10.9 4.3 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2339) DUF2919 PF11143.3 AEO61617.1 - 0.063 13.1 3.0 0.51 10.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2919) DUF2269 PF10027.4 AEO61617.1 - 0.07 12.9 3.4 1.6 8.5 0.3 2.3 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2269) DctQ PF04290.7 AEO61617.1 - 0.42 10.3 7.5 2.6 7.8 0.1 2.9 3 0 0 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component DUF1345 PF07077.6 AEO61617.1 - 2.1 7.8 4.8 2.7 7.4 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1345) DUF1509 PF07420.6 AEO61618.1 - 3.3 6.8 4.5 0.77 8.9 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1509) SPX PF03105.14 AEO61619.1 - 3.2e-10 40.2 0.0 3.2e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 SPX domain CUE PF02845.11 AEO61620.1 - 5.1e-14 51.4 0.0 9.6e-14 50.5 0.0 1.5 1 0 0 1 1 1 1 CUE domain SSP160 PF06933.6 AEO61620.1 - 6.4 4.6 9.4 9 4.1 6.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Snf7 PF03357.16 AEO61621.1 - 2.9e-34 117.9 10.3 3.6e-34 117.6 7.1 1.1 1 0 0 1 1 1 1 Snf7 DUF1843 PF08898.5 AEO61621.1 - 0.93 9.5 11.0 4.1 7.5 2.6 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Enkurin PF13864.1 AEO61621.1 - 1.6 9.0 12.3 1.5 9.0 0.4 3.3 3 1 0 3 3 3 0 Calmodulin-binding DUF2203 PF09969.4 AEO61621.1 - 3.9 7.7 7.0 9.4 6.4 0.3 2.3 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF2293 PF10056.4 AEO61622.1 - 4.8e-29 100.1 0.1 1.4e-28 98.6 0.1 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) Nucleoplasmin PF03066.10 AEO61622.1 - 1.1 8.8 6.2 1.7 8.1 4.3 1.3 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 AEO61622.1 - 4.8 7.4 13.0 10 6.3 9.0 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.8 AEO61622.1 - 8.6 3.9 11.6 12 3.5 8.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi OB_NTP_bind PF07717.11 AEO61623.1 - 1.4e-24 86.0 0.0 2.5e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 AEO61623.1 - 1.1e-21 76.7 0.0 2.4e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 AEO61623.1 - 2.3e-10 40.1 0.0 5e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 AEO61623.1 - 7.9e-05 22.8 0.0 0.00019 21.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 AEO61623.1 - 0.0027 17.2 0.3 0.0088 15.5 0.2 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_29 PF13555.1 AEO61623.1 - 0.017 14.6 0.0 0.044 13.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.7 AEO61623.1 - 0.026 13.6 0.0 0.074 12.1 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin T2SE PF00437.15 AEO61623.1 - 0.045 12.6 0.1 0.2 10.5 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_14 PF13173.1 AEO61623.1 - 0.069 13.0 0.1 7.3 6.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 AEO61623.1 - 0.092 12.6 0.0 0.67 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 AEO61623.1 - 0.11 12.1 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 AEO61623.1 - 0.13 12.5 0.6 0.37 11.0 0.4 1.8 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 AEO61623.1 - 0.18 11.2 0.3 1.4 8.2 0.0 2.4 2 1 1 3 3 3 0 AAA-like domain S10_plectin PF03501.10 AEO61626.1 - 1.1e-37 127.8 0.3 1.3e-37 127.5 0.2 1.1 1 0 0 1 1 1 1 Plectin/S10 domain TrmB PF01978.14 AEO61626.1 - 0.021 14.5 0.1 0.03 14.0 0.1 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Telomere_Sde2 PF13019.1 AEO61627.1 - 1.6e-61 206.7 0.1 2.2e-61 206.2 0.1 1.2 1 0 0 1 1 1 1 Telomere stability and silencing LacI PF00356.16 AEO61627.1 - 0.013 15.0 0.0 0.031 13.8 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family DUF3760 PF12586.3 AEO61627.1 - 0.1 12.4 0.4 0.19 11.5 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3760) YukD PF08817.5 AEO61627.1 - 0.17 12.4 0.7 27 5.4 0.1 2.4 1 1 1 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD Serglycin PF04360.7 AEO61627.1 - 1 9.0 21.6 0.075 12.7 8.6 2.4 1 1 0 2 2 2 0 Serglycin DUF3246 PF11596.3 AEO61627.1 - 1.2 8.3 26.1 0.2 10.9 1.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3246) COX6B PF02297.12 AEO61628.1 - 6.6e-18 64.5 3.7 7.6e-18 64.3 2.6 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.9 AEO61628.1 - 0.0029 16.9 0.2 0.004 16.5 0.1 1.3 1 0 0 1 1 1 1 APOBEC-like C-terminal domain B12D PF06522.6 AEO61629.1 - 3e-11 42.8 0.0 1.2e-10 40.9 0.0 1.8 2 0 0 2 2 2 1 NADH-ubiquinone reductase complex 1 MLRQ subunit DUF624 PF04854.9 AEO61629.1 - 0.12 12.2 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF624 RRM_1 PF00076.17 AEO61630.1 - 9.8e-17 60.3 0.0 1.7e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO61630.1 - 4.6e-16 58.5 0.0 6.9e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO61630.1 - 1.2e-09 37.8 0.0 2.9e-09 36.6 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 AEO61630.1 - 0.013 15.2 0.1 0.027 14.2 0.0 1.6 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 AEO61630.1 - 0.022 14.4 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 Limkain b1 RRM_3 PF08777.6 AEO61630.1 - 0.081 12.7 0.0 0.64 9.8 0.0 2.1 1 1 0 1 1 1 0 RNA binding motif WD40 PF00400.27 AEO61631.1 - 5.1e-22 76.8 5.8 4.3e-05 23.2 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat SRA1 PF07304.6 AEO61631.1 - 1.6e-09 37.7 0.2 1.6e-09 37.7 0.2 3.4 3 1 1 4 4 4 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.2 AEO61631.1 - 2e-07 31.0 0.0 3.7e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 GET2 PF08690.5 AEO61633.1 - 1.4e-10 40.9 0.5 0.00057 19.2 3.1 2.9 2 1 0 2 2 2 2 GET complex subunit GET2 Pex14_N PF04695.8 AEO61633.1 - 0.48 10.4 7.5 0.29 11.1 0.3 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region HATPase_c PF02518.21 AEO61634.1 - 2.9e-28 97.7 0.0 1.9e-27 95.1 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 AEO61634.1 - 1.9e-20 72.9 0.1 5.8e-20 71.3 0.1 1.9 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 AEO61634.1 - 1.2e-19 70.0 1.2 4.1e-19 68.3 0.3 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.1 AEO61634.1 - 4.6e-14 52.8 1.9 1.2e-13 51.5 0.1 2.7 3 0 0 3 3 3 1 AAA ATPase domain GAF_2 PF13185.1 AEO61634.1 - 1.8e-10 41.5 0.0 4.8e-10 40.1 0.0 1.8 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.1 AEO61634.1 - 1.8e-09 37.7 0.0 4.6e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.20 AEO61634.1 - 4.2e-08 32.6 0.0 9.1e-08 31.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO61634.1 - 2.3e-05 23.6 0.0 4.9e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HATPase_c_3 PF13589.1 AEO61634.1 - 0.00023 20.8 0.1 0.00093 18.8 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_12 PF13424.1 AEO61634.1 - 0.00043 20.1 6.1 0.12 12.3 0.6 3.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 AEO61634.1 - 0.00053 19.5 0.7 0.089 12.6 0.0 4.2 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 AEO61634.1 - 0.0044 16.7 0.0 3.5 7.6 0.0 3.4 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF815 PF05673.8 AEO61634.1 - 0.017 14.0 0.4 0.063 12.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NACHT PF05729.7 AEO61634.1 - 0.053 13.1 0.0 2.8 7.5 0.0 2.7 2 0 0 2 2 2 0 NACHT domain NAD_binding_8 PF13450.1 AEO61635.1 - 2e-09 37.3 0.1 3.9e-09 36.4 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 AEO61635.1 - 8.7e-07 28.3 0.0 4.4e-06 26.0 0.0 2.0 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 AEO61635.1 - 0.00027 21.0 0.0 0.0005 20.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 AEO61635.1 - 0.021 13.8 0.1 0.033 13.2 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.9 AEO61635.1 - 0.022 14.6 0.0 0.06 13.2 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 AEO61635.1 - 0.027 12.9 0.1 0.039 12.4 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 AEO61635.1 - 0.063 12.3 0.1 0.15 11.1 0.0 1.6 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.19 AEO61635.1 - 0.19 10.5 0.1 0.27 10.0 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain TPT PF03151.11 AEO61636.1 - 8.7e-30 103.3 17.1 8.7e-30 103.3 11.9 2.6 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 AEO61636.1 - 0.0056 15.6 27.8 0.019 13.8 6.8 2.2 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.15 AEO61636.1 - 0.28 11.2 42.9 0.4 10.7 10.2 2.6 3 0 0 3 3 3 0 EamA-like transporter family ICMT PF04140.9 AEO61636.1 - 1.6 8.9 6.2 0.35 11.1 0.8 2.6 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Ribosomal_L27e PF01777.13 AEO61637.1 - 2.3e-38 130.1 3.7 3.1e-38 129.7 2.6 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 AEO61637.1 - 0.012 15.2 0.1 0.04 13.6 0.1 1.9 1 0 0 1 1 1 0 KOW motif ECM11 PF15463.1 AEO61637.1 - 0.15 12.3 1.5 0.17 12.1 0.2 1.6 2 0 0 2 2 2 0 Extracellular mutant protein 11 DUF2665 PF11654.3 AEO61638.1 - 1.1e-08 34.4 0.0 1.4e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2665) DUF21 PF01595.15 AEO61638.1 - 0.0026 17.0 0.0 0.0029 16.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF21 TPR_11 PF13414.1 AEO61639.1 - 9.7e-05 21.9 2.0 0.019 14.6 0.3 2.6 2 1 0 2 2 2 2 TPR repeat TPR_17 PF13431.1 AEO61639.1 - 0.05 13.8 1.5 0.45 10.8 0.5 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 AEO61639.1 - 0.13 12.9 0.5 0.13 12.9 0.4 2.3 1 1 2 3 3 3 0 Tetratricopeptide repeat Glyoxalase PF00903.20 AEO61640.1 - 2.2e-22 79.3 0.1 8.3e-15 54.9 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 AEO61640.1 - 3.6e-12 46.8 0.0 2.8e-06 27.8 0.1 2.5 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 AEO61640.1 - 4.5e-12 45.9 0.0 1.2e-05 25.2 0.1 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 AEO61640.1 - 4.7e-05 23.3 0.0 0.083 12.7 0.0 3.1 3 0 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 AEO61640.1 - 0.0019 18.1 0.0 0.0041 17.0 0.0 1.5 1 0 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Ssl1 PF04056.9 AEO61641.1 - 3.1e-70 235.7 0.0 1.3e-69 233.6 0.0 1.9 2 0 0 2 2 2 1 Ssl1-like C1_4 PF07975.7 AEO61641.1 - 1e-16 60.6 2.1 1e-16 60.6 1.5 3.0 3 0 0 3 3 3 1 TFIIH C1-like domain VWA_2 PF13519.1 AEO61641.1 - 9.7e-09 35.5 0.0 2.5e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain IBR PF01485.16 AEO61641.1 - 0.013 15.3 2.0 0.013 15.3 1.4 3.2 3 1 0 3 3 3 0 IBR domain Rad50_zn_hook PF04423.9 AEO61641.1 - 9.5 5.7 7.5 4.6 6.8 0.1 3.2 3 0 0 3 3 3 0 Rad50 zinc hook motif HATPase_c PF02518.21 AEO61642.1 - 8.2e-24 83.4 0.1 1.6e-23 82.5 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 AEO61642.1 - 1.3e-21 76.3 0.1 4.2e-21 74.7 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.19 AEO61642.1 - 1.9e-19 69.6 0.0 5.1e-19 68.3 0.0 1.8 2 0 0 2 2 2 1 Response regulator receiver domain PAS_3 PF08447.6 AEO61642.1 - 8.9e-19 67.3 8.5 3.4e-11 43.1 0.2 4.3 4 0 0 4 4 4 3 PAS fold PAS_9 PF13426.1 AEO61642.1 - 1.2e-14 54.5 0.0 8.6e-07 29.2 0.0 3.3 2 1 0 2 2 2 2 PAS domain PAS PF00989.19 AEO61642.1 - 1.1e-08 34.8 0.0 0.0057 16.4 0.0 2.9 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.5 AEO61642.1 - 1.9e-07 31.0 0.1 1.2e-05 25.2 0.0 3.0 2 0 0 2 2 2 1 PAS fold DUF2722 PF10846.3 AEO61643.1 - 4e-05 22.8 0.0 4e-05 22.8 0.0 3.7 2 1 0 3 3 3 1 Protein of unknown function (DUF2722) RabGAP-TBC PF00566.13 AEO61644.1 - 3.5e-33 114.8 2.3 1.4e-32 112.9 0.0 2.2 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DIL PF01843.14 AEO61645.1 - 1.8e-20 72.7 3.7 2.6e-18 65.8 2.5 2.5 1 1 0 1 1 1 1 DIL domain Ank_2 PF12796.2 AEO61645.1 - 1.8e-18 66.6 0.2 1.4e-17 63.8 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 AEO61645.1 - 7.2e-16 57.1 0.0 9.1e-06 25.2 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 AEO61645.1 - 3.4e-13 49.7 0.3 2.7e-07 30.8 0.0 3.8 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 AEO61645.1 - 6.5e-11 42.0 0.0 4.6e-07 29.8 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 AEO61645.1 - 3.7e-09 35.9 0.6 0.033 14.4 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Allantoicase PF03561.10 AEO61646.1 - 5.5e-108 357.0 0.0 7.6e-59 197.5 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat Cytochrom_B561 PF03188.11 AEO61647.1 - 3.2e-16 59.3 4.4 5.8e-16 58.5 3.1 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4079 PF13301.1 AEO61647.1 - 8.5e-05 22.6 10.3 0.011 15.7 3.5 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF4079) PepSY_TM_1 PF13172.1 AEO61647.1 - 0.017 14.8 1.1 0.017 14.8 0.7 2.9 4 0 0 4 4 4 0 PepSY-associated TM helix DUF2162 PF09930.4 AEO61647.1 - 0.036 13.2 2.2 0.1 11.7 0.0 2.2 2 1 0 2 2 2 0 Predicted transporter (DUF2162) DUF2198 PF09964.4 AEO61647.1 - 0.45 10.3 3.1 1.4 8.7 0.3 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2198) DUF4149 PF13664.1 AEO61647.1 - 0.61 10.1 0.1 0.61 10.1 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4149) DUF2306 PF10067.4 AEO61647.1 - 1.6 8.8 9.1 3.6 7.7 0.1 3.3 2 1 1 3 3 3 0 Predicted membrane protein (DUF2306) Ferric_reduct PF01794.14 AEO61647.1 - 4.1 7.5 12.6 0.046 13.7 2.4 2.3 1 1 1 2 2 2 0 Ferric reductase like transmembrane component Chs3p PF12271.3 AEO61648.1 - 4.2e-103 344.3 6.6 6e-103 343.8 4.6 1.2 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit DUF3681 PF12442.3 AEO61648.1 - 0.018 15.2 0.1 0.018 15.2 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3681) DUF347 PF03988.7 AEO61648.1 - 0.054 13.3 0.0 0.054 13.3 0.0 3.6 5 0 0 5 5 5 0 Repeat of Unknown Function (DUF347) DUF4059 PF13268.1 AEO61648.1 - 0.15 12.2 0.0 0.15 12.2 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF4059) Sugar_tr PF00083.19 AEO61649.1 - 2.2e-96 323.1 12.1 2.6e-96 322.9 8.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO61649.1 - 1.3e-27 96.4 40.2 1.9e-26 92.6 11.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 AEO61649.1 - 1.1e-07 30.6 21.8 0.00013 20.5 2.4 2.5 3 0 0 3 3 3 2 MFS/sugar transport protein DUF791 PF05631.9 AEO61649.1 - 0.0036 16.0 0.4 0.0036 16.0 0.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF791) UNC-93 PF05978.11 AEO61649.1 - 0.12 11.9 3.0 7.6 6.0 0.2 2.5 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 Complex1_LYR PF05347.10 AEO61650.1 - 1.3e-07 31.2 1.2 1.3e-07 31.2 0.8 2.3 1 1 1 2 2 2 1 Complex 1 protein (LYR family) DUF4429 PF14472.1 AEO61650.1 - 0.0088 16.3 0.3 0.015 15.5 0.2 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4429) Glyco_hydr_30_2 PF14587.1 AEO61650.1 - 0.029 13.3 0.1 0.032 13.1 0.1 1.1 1 0 0 1 1 1 0 O-Glycosyl hydrolase family 30 Complex1_LYR_1 PF13232.1 AEO61650.1 - 0.54 10.4 11.3 2.3 8.4 7.9 2.0 1 1 0 1 1 1 0 Complex1_LYR-like Mito_carr PF00153.22 AEO61651.1 - 4.2e-44 148.1 7.4 1.8e-16 59.5 0.2 4.2 3 1 0 3 3 3 3 Mitochondrial carrier protein FAM220 PF15487.1 AEO61651.1 - 0.37 10.1 5.1 0.52 9.6 3.5 1.2 1 0 0 1 1 1 0 FAM220 family BAF1_ABF1 PF04684.8 AEO61651.1 - 5.1 5.8 10.1 9 5.0 7.0 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Pkinase PF00069.20 AEO61652.1 - 4e-20 72.0 0.0 4.8e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO61652.1 - 2.1e-07 30.2 0.0 6e-07 28.7 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase AAA PF00004.24 AEO61653.1 - 8e-86 284.9 0.0 1.8e-46 157.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 AEO61653.1 - 1.6e-13 50.2 0.0 9.3e-07 28.1 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 AEO61653.1 - 1.4e-11 44.7 4.9 0.00011 22.2 0.0 4.5 3 2 1 4 4 4 2 AAA ATPase domain AAA_5 PF07728.9 AEO61653.1 - 1.7e-10 40.7 0.3 3.5e-05 23.5 0.1 3.5 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 AEO61653.1 - 7.3e-10 39.0 1.0 0.0042 17.2 0.0 4.5 3 2 0 3 3 2 2 AAA domain AAA_33 PF13671.1 AEO61653.1 - 3e-09 36.8 0.0 0.00061 19.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 AEO61653.1 - 5.2e-09 36.9 0.0 0.0028 18.4 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 AEO61653.1 - 7.5e-09 35.5 0.0 0.0036 17.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 AEO61653.1 - 1.3e-08 34.9 0.0 0.0002 21.3 0.0 3.4 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_28 PF13521.1 AEO61653.1 - 6.4e-07 29.4 0.7 0.033 14.1 0.0 3.5 3 0 0 3 3 3 2 AAA domain TIP49 PF06068.8 AEO61653.1 - 1.2e-06 27.4 0.1 0.02 13.5 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus RNA_helicase PF00910.17 AEO61653.1 - 1.9e-06 27.9 0.0 0.098 12.8 0.0 2.5 2 0 0 2 2 2 2 RNA helicase Zeta_toxin PF06414.7 AEO61653.1 - 2.2e-06 26.9 1.7 0.0037 16.3 0.0 3.2 4 0 0 4 4 3 2 Zeta toxin IstB_IS21 PF01695.12 AEO61653.1 - 3.4e-06 26.6 0.7 0.052 12.9 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein ABC_tran PF00005.22 AEO61653.1 - 4.5e-06 27.0 1.1 0.042 14.1 0.0 3.1 3 1 1 4 4 2 2 ABC transporter AAA_18 PF13238.1 AEO61653.1 - 6.4e-06 26.4 0.0 0.22 11.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 AEO61653.1 - 1.8e-05 24.3 9.8 0.034 13.9 0.1 4.4 4 1 0 4 4 3 2 Part of AAA domain Rad17 PF03215.10 AEO61653.1 - 3.2e-05 22.8 0.0 0.073 11.7 0.0 2.1 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein NACHT PF05729.7 AEO61653.1 - 3.6e-05 23.4 1.3 0.062 12.9 0.1 3.5 3 0 0 3 3 3 1 NACHT domain DUF815 PF05673.8 AEO61653.1 - 4e-05 22.6 0.0 0.014 14.3 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 AEO61653.1 - 5.1e-05 22.5 0.6 0.084 12.0 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 AEO61653.1 - 5.3e-05 22.7 0.0 0.38 10.2 0.0 2.9 2 0 0 2 2 2 2 Sigma-54 interaction domain Vps4_C PF09336.5 AEO61653.1 - 8.7e-05 22.3 0.0 0.0016 18.2 0.0 2.9 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain NB-ARC PF00931.17 AEO61653.1 - 9.3e-05 21.4 0.1 0.14 10.9 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain Sigma54_activ_2 PF14532.1 AEO61653.1 - 0.00015 21.8 0.2 0.12 12.4 0.0 2.9 3 0 0 3 3 2 1 Sigma-54 interaction domain KaiC PF06745.8 AEO61653.1 - 0.00045 19.4 0.0 1.4 8.0 0.0 2.8 3 0 0 3 3 3 2 KaiC SKI PF01202.17 AEO61653.1 - 0.00077 19.3 2.5 0.63 9.8 0.0 3.1 3 0 0 3 3 3 2 Shikimate kinase ATP-synt_ab PF00006.20 AEO61653.1 - 0.0013 18.2 0.0 1.1 8.7 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain UPF0079 PF02367.12 AEO61653.1 - 0.0017 18.0 0.0 0.4 10.3 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_3 PF07726.6 AEO61653.1 - 0.0018 17.8 0.0 1.5 8.4 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Cytidylate_kin2 PF13189.1 AEO61653.1 - 0.0023 17.8 0.0 0.86 9.4 0.0 2.6 2 0 0 2 2 2 1 Cytidylate kinase-like family Arch_ATPase PF01637.13 AEO61653.1 - 0.0025 17.5 0.0 4.9 6.7 0.0 3.3 2 2 1 3 3 3 0 Archaeal ATPase Viral_helicase1 PF01443.13 AEO61653.1 - 0.0026 17.3 0.4 0.6 9.5 0.0 2.6 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.10 AEO61653.1 - 0.0026 17.4 0.1 2.6 7.7 0.0 2.5 2 0 0 2 2 2 1 NTPase AAA_24 PF13479.1 AEO61653.1 - 0.0036 16.8 0.5 4.2 6.9 0.1 3.0 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.1 AEO61653.1 - 0.0044 16.5 0.0 0.12 11.9 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain PhoH PF02562.11 AEO61653.1 - 0.0059 15.8 2.8 1.2 8.3 0.1 3.1 3 0 0 3 3 3 1 PhoH-like protein AAA_25 PF13481.1 AEO61653.1 - 0.0074 15.7 14.6 1.2 8.4 0.2 4.7 3 2 2 5 5 4 1 AAA domain AAA_11 PF13086.1 AEO61653.1 - 0.0081 15.7 0.8 4.9 6.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain Bac_DnaA PF00308.13 AEO61653.1 - 0.0085 15.7 0.0 1.3 8.6 0.0 2.5 2 0 0 2 2 2 1 Bacterial dnaA protein PduV-EutP PF10662.4 AEO61653.1 - 0.0087 15.5 0.0 0.58 9.6 0.0 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation MCM PF00493.18 AEO61653.1 - 0.015 14.0 0.3 0.99 8.1 0.0 2.9 3 0 0 3 3 3 0 MCM2/3/5 family ResIII PF04851.10 AEO61653.1 - 0.028 14.2 0.0 1.6 8.5 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Parvo_NS1 PF01057.12 AEO61653.1 - 0.1 11.4 0.2 4.7 5.9 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Hpr_kinase_C PF07475.7 AEO61653.1 - 0.15 11.3 0.1 1.9 7.7 0.0 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain SRPRB PF09439.5 AEO61653.1 - 0.26 10.4 1.9 14 4.8 0.0 3.0 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit AAA_23 PF13476.1 AEO61653.1 - 1.6 9.0 10.7 1.3 9.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain Cytochrom_C PF00034.16 AEO61654.1 - 1.7e-09 38.3 0.0 2.5e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 AEO61654.1 - 1.5e-08 34.6 2.2 7.4e-08 32.4 1.5 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 AEO61654.1 - 0.0016 17.9 1.5 0.0059 16.0 0.9 2.1 1 1 0 1 1 1 1 Cytochrome c-550 domain Haem_bd PF14376.1 AEO61654.1 - 0.17 11.5 0.3 0.49 10.0 0.0 1.8 2 1 0 2 2 2 0 Haem-binding domain RNase_PH PF01138.16 AEO61656.1 - 3e-14 53.4 0.0 2.9e-13 50.2 0.0 2.2 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 AEO61656.1 - 0.013 15.3 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Chorion_3 PF05387.6 AEO61656.1 - 1.5 8.2 5.2 3.4 7.0 3.6 1.6 1 0 0 1 1 1 0 Chorion family 3 PARP PF00644.15 AEO61657.1 - 7.2e-11 41.9 0.1 1.3e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.21 AEO61657.1 - 4.3e-08 32.6 0.0 1.1e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 AEO61657.1 - 0.0035 17.0 0.0 0.0082 15.8 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic E2 family B COG5 PF10392.4 AEO61658.1 - 7.6e-05 22.6 3.2 0.00014 21.8 0.1 2.4 2 0 0 2 2 2 1 Golgi transport complex subunit 5 LcrG PF07216.7 AEO61658.1 - 0.0055 16.7 3.5 0.019 14.9 2.4 1.9 1 0 0 1 1 1 1 LcrG protein NUDIX PF00293.23 AEO61659.1 - 2e-18 66.3 0.1 2.8e-18 65.8 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain SR-25 PF10500.4 AEO61659.1 - 0.0099 15.3 4.9 0.015 14.7 3.4 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein ATE_C PF04377.10 AEO61660.1 - 3.7e-43 146.6 0.0 5.7e-43 146.0 0.0 1.3 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 AEO61660.1 - 3.2e-18 65.3 4.0 6.6e-18 64.3 2.8 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus DUF648 PF04890.8 AEO61662.1 - 0.0025 17.0 0.1 0.0028 16.8 0.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF648) UPF0542 PF15086.1 AEO61662.1 - 0.0078 15.9 0.1 0.0081 15.8 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0542 ATP-synt_8 PF00895.15 AEO61662.1 - 0.013 15.6 0.0 0.019 15.1 0.0 1.1 1 0 0 1 1 1 0 ATP synthase protein 8 TLC PF03219.9 AEO61662.1 - 0.015 13.8 0.0 0.016 13.7 0.0 1.0 1 0 0 1 1 1 0 TLC ATP/ADP transporter 7TM_GPCR_Sru PF10322.4 AEO61662.1 - 0.016 14.2 0.0 0.019 14.1 0.0 1.0 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sru Nckap1 PF09735.4 AEO61662.1 - 0.024 12.1 0.0 0.028 11.9 0.0 1.0 1 0 0 1 1 1 0 Membrane-associated apoptosis protein Vpu PF00558.14 AEO61662.1 - 0.038 13.5 0.3 0.049 13.1 0.2 1.1 1 0 0 1 1 1 0 Vpu protein 7tm_1 PF00001.16 AEO61662.1 - 0.079 12.0 0.0 0.08 12.0 0.0 1.0 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) PgaD PF13994.1 AEO61662.1 - 0.079 12.4 0.0 0.086 12.3 0.0 1.0 1 0 0 1 1 1 0 PgaD-like protein DUF843 PF05814.6 AEO61662.1 - 0.096 12.4 0.1 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) FAM165 PF14981.1 AEO61662.1 - 4.8 6.7 7.4 9.3 5.8 5.1 1.5 1 1 0 1 1 1 0 FAM165 family Ribosomal_S5_C PF03719.10 AEO61663.1 - 9.5e-18 63.2 0.0 2.4e-17 61.9 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 AEO61663.1 - 4.8e-08 32.6 0.4 7.7e-08 31.9 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Phage_tail PF04630.7 AEO61663.1 - 0.16 11.0 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 Phage major tail protein DASH_Dad3 PF08656.5 AEO61664.1 - 4.4e-27 93.5 0.1 5.9e-27 93.1 0.1 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 Ribosomal_60s PF00428.14 AEO61665.1 - 1.1 9.7 8.2 2.2 8.7 5.7 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Pkinase PF00069.20 AEO61666.1 - 6.4e-71 238.5 0.0 1.2e-70 237.6 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO61666.1 - 1.8e-30 105.8 0.0 3.6e-22 78.6 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 AEO61666.1 - 5.3e-06 25.6 0.0 0.36 9.7 0.0 3.1 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.9 AEO61666.1 - 0.017 14.1 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AEO61666.1 - 0.049 13.3 0.0 1.3 8.7 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Retinal PF15449.1 AEO61666.1 - 1.4 6.4 5.9 1.8 6.1 4.1 1.1 1 0 0 1 1 1 0 Retinal protein zf-C2H2_4 PF13894.1 AEO61667.1 - 0.28 11.6 1.3 2.7 8.5 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger adh_short PF00106.20 AEO61668.1 - 6.9e-17 61.8 1.5 1.1e-16 61.2 1.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO61668.1 - 2.2e-08 33.9 0.3 3.6e-08 33.2 0.2 1.5 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 AEO61668.1 - 1.6e-07 31.3 0.0 2.1e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase zf-CCCH PF00642.19 AEO61669.1 - 4.3e-06 26.2 0.9 4.3e-06 26.2 0.6 2.3 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ost4 PF10215.4 AEO61670.1 - 9.6e-18 63.3 0.2 1.1e-17 63.1 0.2 1.1 1 0 0 1 1 1 1 Oligosaccaryltransferase RRM_1 PF00076.17 AEO61671.1 - 3.9e-16 58.4 0.0 6.5e-16 57.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO61671.1 - 3.3e-13 49.4 0.0 5.2e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO61671.1 - 1.2e-07 31.5 0.0 1.9e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 AEO61671.1 - 1.6e-05 25.2 3.9 1.6e-05 25.2 2.7 3.1 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 Glyco_hydro_43 PF04616.9 AEO61672.1 - 5.7e-33 114.2 0.5 8e-33 113.7 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CS PF04969.11 AEO61673.1 - 4.9e-11 43.0 0.2 7.6e-11 42.4 0.1 1.4 1 0 0 1 1 1 1 CS domain HSP20 PF00011.16 AEO61673.1 - 0.1 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Hsp20/alpha crystallin family Snf7 PF03357.16 AEO61674.1 - 1.3e-19 70.2 1.6 1.3e-19 70.2 1.1 2.1 1 1 1 2 2 2 1 Snf7 DUF3484 PF11983.3 AEO61674.1 - 0.0017 19.1 3.8 0.0017 19.1 2.7 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3484) MAT1 PF06391.8 AEO61674.1 - 0.019 14.5 1.2 0.019 14.5 0.8 2.1 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 ABC_trans_N PF14510.1 AEO61674.1 - 0.037 14.0 0.4 2 8.5 0.1 2.5 2 0 0 2 2 2 0 ABC-transporter extracellular N-terminal DUF4611 PF15387.1 AEO61674.1 - 1 9.5 7.6 4.5 7.4 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) PBP_sp32 PF07222.7 AEO61674.1 - 1.1 8.3 6.2 1.9 7.5 4.3 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 APG6 PF04111.7 AEO61674.1 - 8.1 5.3 13.6 7.9 5.4 3.8 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 MxiH PF09392.5 AEO61674.1 - 8.5 7.0 8.9 29 5.3 0.5 3.0 2 1 1 3 3 3 0 Type III secretion needle MxiH like CENP-U PF13097.1 AEO61676.1 - 0.031 14.2 2.5 0.044 13.7 1.7 1.3 1 0 0 1 1 1 0 CENP-A nucleosome associated complex (NAC) subunit DUF899 PF05988.7 AEO61676.1 - 1.2 8.5 3.8 1.8 7.9 2.6 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) DNA_pol3_a_NII PF11490.3 AEO61678.1 - 4.2 6.9 14.9 13 5.4 10.3 1.8 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II PIG-H PF10181.4 AEO61679.1 - 3.8e-26 90.5 0.0 7.9e-26 89.4 0.0 1.5 1 1 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component GRP PF07172.6 AEO61679.1 - 0.051 14.0 0.1 0.051 14.0 0.0 3.2 3 0 0 3 3 3 0 Glycine rich protein family Glyco_tranf_2_3 PF13641.1 AEO61679.1 - 0.14 11.9 0.3 0.26 11.0 0.2 1.5 1 1 0 1 1 1 0 Glycosyltransferase like family 2 PseudoU_synth_1 PF01416.15 AEO61680.1 - 1.9e-24 86.0 0.0 1.9e-21 76.4 0.0 3.1 2 1 0 2 2 2 2 tRNA pseudouridine synthase Ras PF00071.17 AEO61681.1 - 1.9e-16 59.8 0.0 1.6e-13 50.3 0.0 2.1 1 1 1 2 2 2 2 Ras family Miro PF08477.8 AEO61681.1 - 8e-07 29.5 0.1 0.011 16.2 0.0 2.2 1 1 1 2 2 2 2 Miro-like protein AAA_16 PF13191.1 AEO61681.1 - 0.0057 16.6 0.0 0.008 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain G-alpha PF00503.15 AEO61681.1 - 0.02 13.5 0.0 0.032 12.9 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit NACHT PF05729.7 AEO61681.1 - 0.031 13.9 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.1 AEO61681.1 - 0.047 13.2 0.0 0.087 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.13 AEO61681.1 - 0.072 12.1 0.0 0.092 11.7 0.0 1.1 1 0 0 1 1 1 0 Septin Arf PF00025.16 AEO61681.1 - 0.075 12.2 0.0 5.5 6.1 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family RNA_helicase PF00910.17 AEO61681.1 - 0.077 13.1 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 AEO61681.1 - 0.089 13.0 0.0 0.13 12.5 0.0 1.3 1 1 0 1 1 1 0 ABC transporter RNA_pol_Rpb4 PF03874.11 AEO61682.1 - 1.5e-27 95.9 3.0 1.8e-27 95.6 2.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 DUF1539 PF07560.6 AEO61682.1 - 0.078 12.8 0.5 0.12 12.2 0.3 1.4 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1539) Pribosyl_synth PF14572.1 AEO61683.1 - 4.8e-39 134.0 0.3 1.1e-38 132.8 0.2 1.6 1 1 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 AEO61683.1 - 3.7e-28 97.5 0.0 9.5e-28 96.2 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 AEO61683.1 - 2.9e-12 46.3 0.0 9.1e-12 44.8 0.0 1.8 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 AEO61683.1 - 0.0014 17.8 0.0 0.0027 16.9 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase SLAC1 PF03595.12 AEO61685.1 - 1.8e-43 148.5 17.6 2e-43 148.3 12.2 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF202 PF02656.10 AEO61685.1 - 0.2 11.9 8.6 0.15 12.2 1.3 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF202) RasGEF PF00617.14 AEO61686.1 - 1e-45 155.8 0.1 1.5e-45 155.2 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain Miro PF08477.8 AEO61686.1 - 5.3e-14 52.7 0.0 1.3e-13 51.4 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein RasGEF_N PF00618.15 AEO61686.1 - 5.9e-12 45.6 0.0 1.1e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 RasGEF N-terminal motif Ras PF00071.17 AEO61686.1 - 0.0007 19.0 0.0 0.0082 15.5 0.0 2.3 1 1 0 1 1 1 1 Ras family GTP_EFTU PF00009.22 AEO61686.1 - 0.00098 18.6 0.0 0.4 10.1 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 AEO61686.1 - 0.0038 17.0 0.0 0.0079 16.0 0.0 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 AEO61686.1 - 0.013 15.4 0.0 0.032 14.1 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.1 AEO61686.1 - 0.014 15.5 0.2 0.23 11.6 0.0 2.9 4 0 0 4 4 4 0 AAA domain ABC_tran PF00005.22 AEO61686.1 - 0.017 15.4 0.0 0.055 13.7 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_17 PF13207.1 AEO61686.1 - 0.019 15.7 0.0 0.095 13.5 0.0 2.3 1 0 0 1 1 1 0 AAA domain IIGP PF05049.8 AEO61686.1 - 0.024 13.4 1.3 0.048 12.4 0.0 1.9 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_16 PF13191.1 AEO61686.1 - 0.053 13.4 2.1 0.67 9.9 0.0 3.1 3 1 0 3 3 3 0 AAA ATPase domain AAA_18 PF13238.1 AEO61686.1 - 0.065 13.5 0.0 0.17 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 AEO61686.1 - 0.089 12.3 0.0 1.1 8.7 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MobB PF03205.9 AEO61686.1 - 0.15 11.7 0.0 0.74 9.5 0.0 2.2 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B zf-HIT PF04438.11 AEO61688.1 - 7e-12 44.7 10.4 1.2e-11 44.0 7.2 1.4 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.13 AEO61688.1 - 2.1e-05 24.2 8.0 3.2e-05 23.7 5.5 1.3 1 0 0 1 1 1 1 MYND finger Mit_ribos_Mrp51 PF11709.3 AEO61688.1 - 0.042 13.0 0.0 0.059 12.5 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit zf-B_box PF00643.19 AEO61688.1 - 0.16 11.8 3.6 0.25 11.2 2.5 1.3 1 0 0 1 1 1 0 B-box zinc finger Nfu_N PF08712.6 AEO61689.1 - 9.5e-30 102.0 0.0 2.4e-29 100.7 0.0 1.7 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 AEO61689.1 - 9.7e-21 73.3 0.0 1.6e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 NifU-like domain Ribosomal_60s PF00428.14 AEO61689.1 - 0.084 13.2 2.3 0.16 12.3 1.6 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein PSP1 PF04468.7 AEO61690.1 - 3.1e-31 107.2 0.7 4.9e-31 106.5 0.5 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region DUF4543 PF15076.1 AEO61691.1 - 0.07 13.1 0.0 2.6 8.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4543) Bac_GDH PF05088.7 AEO61691.1 - 0.09 10.1 0.1 0.11 9.8 0.1 1.0 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase Ribosomal_L15e PF00827.12 AEO61692.1 - 4.4e-92 306.8 12.3 5e-92 306.6 8.5 1.0 1 0 0 1 1 1 1 Ribosomal L15 PUF PF00806.14 AEO61693.1 - 1.1e-63 207.3 12.0 3.7e-08 32.4 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat TylF PF05711.6 AEO61693.1 - 0.04 13.0 0.1 0.04 13.0 0.1 1.6 2 0 0 2 2 2 0 Macrocin-O-methyltransferase (TylF) Suf PF05843.9 AEO61693.1 - 3 7.4 18.8 1.4 8.5 9.7 2.6 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) Ycf1 PF05758.7 AEO61693.1 - 3.8 5.1 10.0 29 2.1 0.0 2.2 2 0 0 2 2 2 0 Ycf1 Serinc PF03348.10 AEO61693.1 - 5.1 5.6 7.4 8.4 4.9 5.1 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4407 PF14362.1 AEO61693.1 - 7.1 5.4 11.3 11 4.8 7.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RNA_pol_Rpb2_6 PF00562.23 AEO61694.1 - 1.5e-112 376.1 0.0 2.2e-112 375.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 AEO61694.1 - 2.8e-47 160.2 0.0 5e-47 159.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 AEO61694.1 - 8.1e-30 102.9 0.5 1.8e-29 101.7 0.4 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.9 AEO61694.1 - 2.7e-29 101.9 0.0 6.8e-29 100.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 AEO61694.1 - 7.9e-21 73.5 0.0 1.7e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.8 AEO61694.1 - 2e-19 69.1 0.0 4.8e-19 67.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 AEO61694.1 - 2.2e-11 43.5 0.4 5.6e-11 42.2 0.3 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RelB PF04221.7 AEO61695.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 RelB antitoxin NOA36 PF06524.7 AEO61695.1 - 2.3 7.4 5.8 3.1 6.9 4.0 1.1 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 AEO61695.1 - 3.9 6.9 11.3 6.8 6.1 7.8 1.3 1 0 0 1 1 1 0 Nucleoplasmin Mito_fiss_reg PF05308.6 AEO61695.1 - 4.4 6.5 10.7 11 5.2 7.4 1.7 1 0 0 1 1 1 0 Mitochondrial fission regulator Adeno_E3_CR2 PF02439.10 AEO61697.1 - 0.039 13.4 0.1 0.075 12.5 0.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF2217 PF10265.4 AEO61697.1 - 8.2 5.0 12.0 14 4.2 8.3 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Carn_acyltransf PF00755.15 AEO61698.1 - 2.3e-170 567.6 0.0 1.2e-153 512.3 0.0 2.0 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase SET PF00856.23 AEO61699.1 - 0.043 14.1 0.0 0.081 13.2 0.0 1.5 1 0 0 1 1 1 0 SET domain Ras PF00071.17 AEO61701.1 - 1.5e-65 219.4 0.5 1.8e-65 219.2 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AEO61701.1 - 1.2e-21 77.4 0.0 1.7e-21 76.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AEO61701.1 - 2.8e-16 59.2 0.1 3.3e-16 58.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 AEO61701.1 - 1.2e-05 24.8 0.2 2.8e-05 23.6 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 AEO61701.1 - 1.7e-05 24.0 0.1 2.4e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 AEO61701.1 - 7.1e-05 22.7 0.0 0.00015 21.7 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 AEO61701.1 - 0.00041 19.6 0.0 0.0007 18.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 AEO61701.1 - 0.00062 19.0 0.1 0.0045 16.2 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA PF00004.24 AEO61701.1 - 0.0012 19.0 0.1 0.088 13.0 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AEO61701.1 - 0.0012 18.9 0.0 0.0022 18.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 AEO61701.1 - 0.0094 15.1 0.0 0.025 13.7 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 AEO61701.1 - 0.019 14.9 0.1 0.066 13.2 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 AEO61701.1 - 0.024 14.5 0.1 0.076 12.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain Septin PF00735.13 AEO61701.1 - 0.037 13.0 0.1 0.21 10.5 0.0 2.0 2 0 0 2 2 2 0 Septin AAA_29 PF13555.1 AEO61701.1 - 0.037 13.5 0.0 0.11 12.0 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 AEO61701.1 - 0.06 13.0 0.0 0.098 12.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 AEO61701.1 - 0.09 13.0 0.0 0.15 12.3 0.0 1.6 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.4 AEO61701.1 - 0.094 12.1 0.1 0.53 9.7 0.0 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation WD40 PF00400.27 AEO61703.1 - 1.8e-19 68.7 18.2 4e-05 23.3 0.0 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 AEO61703.1 - 0.0062 14.7 0.6 0.12 10.4 0.1 2.3 3 0 0 3 3 3 1 Nucleoporin Nup120/160 DUF627 PF04781.7 AEO61703.1 - 0.018 14.6 0.0 0.037 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF627) Sigma70_r1_2 PF00140.15 AEO61703.1 - 0.042 13.5 0.9 0.073 12.7 0.6 1.4 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 WD40 PF00400.27 AEO61704.1 - 2.1e-22 78.1 1.9 1.1e-07 31.4 0.0 7.0 6 0 0 6 6 6 4 WD domain, G-beta repeat DUF3639 PF12341.3 AEO61704.1 - 1.4e-09 37.7 2.3 5.3e-09 35.9 1.6 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3639) Coatomer_WDAD PF04053.9 AEO61704.1 - 0.00015 20.7 0.0 0.00038 19.3 0.0 1.5 1 1 0 1 1 1 1 Coatomer WD associated region eIF2A PF08662.6 AEO61704.1 - 0.0017 18.1 0.0 0.016 14.9 0.0 2.3 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 AEO61704.1 - 0.025 12.4 0.1 0.069 10.9 0.0 1.6 1 1 1 2 2 2 0 IKI3 family Macoilin PF09726.4 AEO61704.1 - 0.52 8.5 2.7 0.72 8.0 1.8 1.1 1 0 0 1 1 1 0 Transmembrane protein HSF_DNA-bind PF00447.12 AEO61706.1 - 2.9e-28 98.0 1.6 3.7e-28 97.7 1.1 1.1 1 0 0 1 1 1 1 HSF-type DNA-binding Ets PF00178.17 AEO61706.1 - 0.073 13.2 0.1 0.1 12.7 0.1 1.3 1 0 0 1 1 1 0 Ets-domain Ashwin PF15323.1 AEO61706.1 - 0.082 12.9 3.2 0.086 12.8 2.2 1.2 1 0 0 1 1 1 0 Developmental protein DUF605 PF04652.11 AEO61706.1 - 2.3 7.5 14.7 2.6 7.3 10.2 1.1 1 0 0 1 1 1 0 Vta1 like TSGP1 PF07771.6 AEO61708.1 - 1.3 8.9 8.1 0.42 10.5 3.1 2.1 2 0 0 2 2 2 0 Tick salivary peptide group 1 Mucin PF01456.12 AEO61708.1 - 3.3 7.4 23.6 12 5.6 16.3 2.0 1 0 0 1 1 1 0 Mucin-like glycoprotein ATP-grasp_2 PF08442.5 AEO61710.1 - 1.5e-78 262.8 0.9 1.9e-78 262.5 0.1 1.5 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.14 AEO61710.1 - 1.7e-26 92.6 0.3 3.1e-26 91.8 0.2 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 AEO61710.1 - 4.4e-09 35.8 0.1 1.1e-08 34.5 0.1 1.7 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 AEO61710.1 - 0.00089 18.8 0.8 0.007 15.9 0.1 2.5 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Peripla_BP_2 PF01497.13 AEO61710.1 - 0.0027 16.8 0.1 0.005 16.0 0.1 1.4 1 0 0 1 1 1 1 Periplasmic binding protein ATP-grasp_4 PF13535.1 AEO61710.1 - 0.0029 17.3 0.0 0.0053 16.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain PepSY_2 PF13670.1 AEO61711.1 - 2.2 8.2 11.4 1.7 8.6 5.4 2.4 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain RabGAP-TBC PF00566.13 AEO61712.1 - 2.6e-47 161.0 1.5 6.4e-46 156.5 0.2 2.4 2 0 0 2 2 2 1 Rab-GTPase-TBC domain CCDC155 PF14662.1 AEO61712.1 - 0.18 11.4 33.4 0.14 11.6 6.5 2.8 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 Microtub_assoc PF07989.6 AEO61712.1 - 0.45 10.3 20.5 0.11 12.3 2.4 3.5 2 1 1 3 3 3 0 Microtubule associated HALZ PF02183.13 AEO61712.1 - 1.3 8.7 21.9 0.12 12.1 0.3 4.0 4 0 0 4 4 4 0 Homeobox associated leucine zipper bZIP_1 PF00170.16 AEO61712.1 - 4.5 7.3 20.1 9.2 6.3 3.6 3.9 2 1 0 2 2 2 0 bZIP transcription factor Ribosomal_S8e PF01201.17 AEO61713.1 - 4.7e-49 165.9 0.5 5.4e-49 165.7 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e DUF913 PF06025.7 AEO61714.1 - 8.4e-133 442.7 0.0 8.4e-133 442.7 0.0 3.8 5 0 0 5 5 5 1 Domain of Unknown Function (DUF913) HECT PF00632.20 AEO61714.1 - 8.6e-99 330.6 0.1 3.7e-98 328.5 0.0 2.1 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.7 AEO61714.1 - 4.3e-94 315.5 0.0 4.3e-94 315.5 0.0 3.2 3 0 0 3 3 3 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 AEO61714.1 - 2.2e-33 114.3 8.5 2.2e-33 114.3 5.9 4.3 4 1 0 4 4 4 1 Domain of unknown function (DUF4414) UBA PF00627.26 AEO61714.1 - 1.2e-05 24.9 0.2 0.00011 21.9 0.1 2.6 2 0 0 2 2 2 1 UBA/TS-N domain PSDC PF12588.3 AEO61714.1 - 0.026 14.1 0.0 11 5.6 0.0 3.6 3 0 0 3 3 3 0 Phophatidylserine decarboxylase DUF3915 PF13054.1 AEO61714.1 - 0.25 11.3 0.0 0.25 11.3 0.0 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF3915) Ribosomal_S6e PF01092.14 AEO61715.1 - 1.6e-59 199.0 0.0 3.4e-59 198.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e EF-1_beta_acid PF10587.4 AEO61715.1 - 1.2 9.3 4.3 2.8 8.1 3.0 1.6 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region Diphthamide_syn PF01866.12 AEO61716.1 - 8.9e-114 379.8 0.0 1.1e-113 379.5 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Ctf8 PF09696.5 AEO61717.1 - 1.7e-32 111.7 0.0 2.4e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 Ctf8 Aldose_epim PF01263.15 AEO61718.1 - 1.7e-49 168.5 0.0 2.3e-49 168.1 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase ATP-synt_ab PF00006.20 AEO61719.1 - 3.8e-61 206.3 0.0 5.1e-61 205.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 AEO61719.1 - 2.2e-16 60.3 0.0 3.9e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 AEO61719.1 - 8.1e-11 41.9 1.5 1.7e-10 40.9 1.0 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 AEO61719.1 - 0.00018 21.3 0.6 0.00039 20.2 0.4 1.5 1 0 0 1 1 1 1 HAS barrel domain Pro_isomerase PF00160.16 AEO61720.1 - 2.1e-41 141.6 0.0 4.6e-41 140.6 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HSF_DNA-bind PF00447.12 AEO61721.1 - 6.6e-28 96.9 0.2 1.5e-27 95.7 0.1 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Pro_isomerase PF00160.16 AEO61722.1 - 1.2e-45 155.4 0.0 1.4e-45 155.2 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Arrestin_C PF02752.17 AEO61723.1 - 2.2e-16 60.1 0.0 2.5e-14 53.5 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain tRNA_int_end_N2 PF12928.2 AEO61724.1 - 4.3e-14 51.7 0.0 7.7e-14 50.9 0.0 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 AEO61724.1 - 0.071 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain zf-ZPR1 PF03367.8 AEO61726.1 - 1.9e-104 345.7 0.3 1.1e-51 174.2 0.1 2.7 2 1 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.14 AEO61726.1 - 0.63 9.7 2.9 7.5 6.2 0.1 2.5 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF866 PF05907.8 AEO61727.1 - 5.5e-50 169.0 0.4 6e-50 168.8 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Ribosomal_S26e PF01283.14 AEO61727.1 - 0.016 15.4 1.3 0.46 10.7 0.1 2.2 1 1 1 2 2 2 0 Ribosomal protein S26e PHD PF00628.24 AEO61727.1 - 0.15 11.7 1.3 0.41 10.3 0.9 1.8 1 1 0 1 1 1 0 PHD-finger Zn_Tnp_IS1595 PF12760.2 AEO61727.1 - 0.36 10.6 3.3 0.95 9.3 2.3 1.7 1 1 0 1 1 1 0 Transposase zinc-ribbon domain Sgf11 PF08209.6 AEO61727.1 - 0.55 9.5 3.4 1.8 7.9 0.1 2.5 2 1 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zinc_ribbon_4 PF13717.1 AEO61727.1 - 1.3 8.7 4.4 3.9 7.2 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 AEO61727.1 - 1.5 8.4 4.5 3.6 7.2 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain WW PF00397.21 AEO61729.1 - 3.4e-08 33.1 0.4 7.6e-08 32.0 0.3 1.6 1 0 0 1 1 1 1 WW domain DUF605 PF04652.11 AEO61729.1 - 0.004 16.6 8.8 0.0063 15.9 6.1 1.4 1 0 0 1 1 1 1 Vta1 like Pga1 PF10333.4 AEO61730.1 - 0.038 13.6 0.1 0.12 12.0 0.0 1.9 2 1 0 2 2 2 0 GPI-Mannosyltransferase II co-activator HAMP PF00672.20 AEO61730.1 - 0.097 12.8 0.5 0.097 12.8 0.3 1.9 2 0 0 2 2 2 0 HAMP domain ABC_membrane_2 PF06472.10 AEO61731.1 - 2e-106 355.2 2.5 2e-106 355.2 1.8 1.6 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 AEO61731.1 - 1.7e-18 67.2 0.0 3.2e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 AEO61731.1 - 0.00054 20.0 0.0 0.0015 18.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AEO61731.1 - 0.016 15.2 0.1 0.068 13.1 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 AEO61731.1 - 0.033 13.7 0.0 0.098 12.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Glyco_transf_22 PF03901.12 AEO61731.1 - 0.043 12.8 1.3 0.074 12.0 0.9 1.3 1 0 0 1 1 1 0 Alg9-like mannosyltransferase family SMC_N PF02463.14 AEO61731.1 - 0.058 12.6 0.2 0.24 10.6 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 AEO61731.1 - 0.14 12.4 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 AEO61731.1 - 0.19 10.8 0.0 0.38 9.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Mg_chelatase PF01078.16 AEO61731.1 - 0.2 10.8 0.1 0.78 8.8 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF3436 PF11918.3 AEO61732.1 - 0.0066 16.6 0.3 5.2 7.3 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF3436) G_glu_transpept PF01019.16 AEO61733.1 - 1.9e-163 544.6 0.2 2.1e-163 544.4 0.1 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Actin PF00022.14 AEO61734.1 - 1.8e-87 293.3 0.0 4e-87 292.1 0.0 1.5 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 AEO61734.1 - 0.082 11.4 0.1 2.4 6.6 0.0 2.2 2 0 0 2 2 2 0 MreB/Mbl protein Asparaginase_2 PF01112.13 AEO61735.1 - 1.4e-28 99.5 8.1 4.5e-15 55.1 0.0 2.6 2 1 1 3 3 3 2 Asparaginase Tfb4 PF03850.9 AEO61736.1 - 5.3e-82 275.1 7.3 5.4e-59 199.7 0.0 2.0 2 0 0 2 2 2 2 Transcription factor Tfb4 UNC45-central PF11701.3 AEO61737.1 - 4.7e-42 143.3 0.0 3.3e-41 140.5 0.0 2.6 2 1 0 2 2 2 1 Myosin-binding striated muscle assembly central HEAT_2 PF13646.1 AEO61737.1 - 0.00074 19.7 14.2 0.44 10.8 0.2 5.6 3 1 2 5 5 5 3 HEAT repeats DUF4547 PF15080.1 AEO61737.1 - 0.054 12.9 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4547) Arm PF00514.18 AEO61737.1 - 0.13 12.1 7.7 5.2 7.0 0.2 6.2 6 1 0 6 6 6 0 Armadillo/beta-catenin-like repeat RasGEF_N_2 PF14663.1 AEO61737.1 - 1.3 8.9 6.0 19 5.2 0.0 4.1 5 0 0 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain ERCC4 PF02732.10 AEO61738.1 - 6.7e-21 74.5 0.0 1.2e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain RE_Eco47II PF09553.5 AEO61738.1 - 0.057 12.5 0.1 0.11 11.5 0.1 1.5 1 0 0 1 1 1 0 Eco47II restriction endonuclease DUF4637 PF15470.1 AEO61738.1 - 0.071 12.7 8.3 0.017 14.7 3.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) CAF-1_p150 PF11600.3 AEO61738.1 - 2.3 7.5 24.0 0.47 9.7 13.2 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DDHD PF02862.12 AEO61738.1 - 3.3 7.4 6.0 7.2 6.3 4.1 1.5 1 0 0 1 1 1 0 DDHD domain AMP-binding PF00501.23 AEO61739.1 - 1.1e-90 303.9 0.2 1.4e-90 303.6 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 AEO61739.1 - 1.5e-21 77.1 1.2 1e-19 71.2 0.2 3.3 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain Reprolysin_5 PF13688.1 AEO61740.1 - 1.8e-60 204.2 4.7 5.2e-60 202.7 3.3 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 AEO61740.1 - 5.1e-48 163.3 0.5 1.1e-47 162.3 0.4 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 AEO61740.1 - 1.6e-47 161.6 0.2 2.7e-47 160.9 0.2 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 AEO61740.1 - 2.3e-19 70.1 0.0 2.3e-19 70.1 0.0 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 AEO61740.1 - 3.7e-19 68.7 28.4 3.7e-19 68.7 19.7 4.4 3 1 0 3 3 3 1 Disintegrin Pep_M12B_propep PF01562.14 AEO61740.1 - 5.3e-05 23.0 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin PF01421.14 AEO61740.1 - 9.9e-05 22.0 10.0 9.9e-05 22.0 6.9 3.8 2 1 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease HxxPF_rpt PF13745.1 AEO61740.1 - 0.14 12.4 0.0 0.51 10.6 0.0 1.9 2 0 0 2 2 2 0 HxxPF-repeated domain Nif11 PF07862.6 AEO61743.1 - 0.028 14.3 0.1 0.056 13.3 0.1 1.5 1 0 0 1 1 1 0 Nitrogen fixation protein of unknown function Ribosomal_L3 PF00297.17 AEO61744.1 - 1.4e-118 395.0 10.7 1.7e-118 394.7 7.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 TPR_1 PF00515.23 AEO61745.1 - 3.2e-56 184.7 31.7 4.2e-08 32.4 0.0 10.7 11 1 0 11 11 11 8 Tetratricopeptide repeat TPR_2 PF07719.12 AEO61745.1 - 5.8e-53 172.6 21.3 7.9e-06 25.4 0.0 10.5 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_11 PF13414.1 AEO61745.1 - 1.4e-45 152.7 25.5 6.1e-11 41.8 0.9 6.4 2 2 2 6 6 6 6 TPR repeat TPR_8 PF13181.1 AEO61745.1 - 2.3e-41 136.4 21.1 2.5e-06 26.8 0.6 10.2 8 1 2 10 10 10 8 Tetratricopeptide repeat TPR_16 PF13432.1 AEO61745.1 - 4.8e-34 116.3 18.1 1.6e-08 35.0 0.1 6.9 4 2 2 7 7 6 6 Tetratricopeptide repeat TPR_14 PF13428.1 AEO61745.1 - 2.6e-33 111.4 12.7 6.6e-05 23.1 0.0 10.0 3 2 7 10 10 10 9 Tetratricopeptide repeat TPR_12 PF13424.1 AEO61745.1 - 1.5e-29 101.7 25.5 5e-06 26.3 1.7 7.3 2 2 6 8 8 8 8 Tetratricopeptide repeat TPR_17 PF13431.1 AEO61745.1 - 1.7e-28 96.4 19.7 0.001 19.1 0.1 10.9 10 1 1 11 11 11 7 Tetratricopeptide repeat TPR_6 PF13174.1 AEO61745.1 - 3.3e-24 83.6 12.9 0.026 14.9 0.9 10.1 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.1 AEO61745.1 - 5.9e-24 84.1 15.5 0.00028 21.1 0.1 6.9 5 2 0 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.1 AEO61745.1 - 1.1e-23 81.0 10.2 0.0031 17.2 0.0 9.7 9 1 0 9 9 9 5 Tetratricopeptide repeat TPR_9 PF13371.1 AEO61745.1 - 1.3e-14 53.7 15.2 0.0056 16.4 0.2 6.8 1 1 7 8 8 8 4 Tetratricopeptide repeat Apc3 PF12895.2 AEO61745.1 - 3.5e-14 52.7 12.9 1.8e-08 34.3 1.7 4.3 2 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 AEO61745.1 - 2.3e-13 49.8 9.1 5.9e-05 22.2 0.4 4.6 1 1 4 5 5 5 3 Tetratricopeptide repeat TPR_20 PF14561.1 AEO61745.1 - 5.1e-05 23.3 2.5 0.23 11.6 0.0 4.8 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_21 PF09976.4 AEO61745.1 - 0.034 14.0 19.0 0.65 9.9 0.0 5.0 4 2 2 6 6 6 0 Tetratricopeptide repeat MIT PF04212.13 AEO61745.1 - 0.069 13.0 14.3 1.8 8.5 1.0 5.6 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain ChAPs PF09295.5 AEO61745.1 - 0.21 10.3 2.3 1.3 7.7 0.2 2.9 3 1 1 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) SNAP PF14938.1 AEO61745.1 - 2.7 7.0 16.9 13 4.8 0.3 4.9 2 2 1 3 3 3 0 Soluble NSF attachment protein, SNAP NARP1 PF12569.3 AEO61745.1 - 6.9 5.2 14.1 1.6 7.3 0.0 4.0 4 1 0 4 4 4 0 NMDA receptor-regulated protein 1 DUF1751 PF08551.5 AEO61747.1 - 1.6e-28 98.9 2.2 3.9e-28 97.6 1.5 1.7 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) DUF3464 PF11947.3 AEO61747.1 - 0.54 9.7 4.2 0.2 11.1 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) Rhomboid PF01694.17 AEO61747.1 - 0.58 10.1 12.6 0.14 12.1 6.4 1.7 2 0 0 2 2 2 0 Rhomboid family WD40 PF00400.27 AEO61748.1 - 3.6e-17 61.5 5.5 2e-05 24.2 0.0 6.7 5 1 1 6 6 6 6 WD domain, G-beta repeat LisH PF08513.6 AEO61748.1 - 7.6e-08 31.8 0.1 1.7e-07 30.7 0.1 1.6 1 0 0 1 1 1 1 LisH Apc4_WD40 PF12894.2 AEO61748.1 - 0.0051 16.2 1.4 0.075 12.5 0.0 3.5 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain MFS_1 PF07690.11 AEO61749.1 - 1.9e-36 125.5 41.2 1.9e-36 125.5 28.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO61749.1 - 6.2e-11 41.5 12.2 6.2e-11 41.5 8.4 1.9 2 1 0 2 2 2 1 Sugar (and other) transporter DUF1072 PF06380.6 AEO61749.1 - 0.11 12.1 0.3 0.43 10.2 0.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1072) Sugar_tr PF00083.19 AEO61750.1 - 1.1e-41 142.9 13.1 1.2e-41 142.7 9.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO61750.1 - 2.1e-05 23.4 23.1 2.8e-05 23.0 16.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 AEO61750.1 - 2.6 6.3 18.4 0.75 8.1 3.3 2.1 2 0 0 2 2 2 0 MFS/sugar transport protein adh_short PF00106.20 AEO61751.1 - 4.7e-28 98.1 5.3 9.7e-28 97.1 3.7 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 AEO61751.1 - 2e-15 57.2 0.0 3.1e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 AEO61751.1 - 7.8e-12 45.2 6.3 2e-10 40.6 4.4 2.6 1 1 1 2 2 2 1 KR domain Epimerase PF01370.16 AEO61751.1 - 0.0039 16.6 0.0 0.0051 16.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family HDPD PF02924.9 AEO61751.1 - 0.037 13.8 1.2 0.086 12.6 0.2 1.9 2 0 0 2 2 2 0 Bacteriophage lambda head decoration protein D Pkinase PF00069.20 AEO61752.1 - 1.1e-08 34.5 0.0 3.6e-08 32.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO61752.1 - 0.0043 16.1 0.0 0.076 12.0 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase WD40 PF00400.27 AEO61754.1 - 1e-33 113.9 6.7 2.9e-09 36.4 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Sof1 PF04158.9 AEO61754.1 - 4e-32 110.1 16.6 6.8e-32 109.3 11.5 1.4 1 0 0 1 1 1 1 Sof1-like domain BBS2_Mid PF14783.1 AEO61754.1 - 2.5e-05 24.0 0.2 0.41 10.4 0.0 4.6 4 2 2 6 6 6 2 Ciliary BBSome complex subunit 2, middle region DUF3022 PF11226.3 AEO61754.1 - 0.011 15.6 0.6 0.021 14.7 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3022) PQQ_3 PF13570.1 AEO61754.1 - 0.053 13.8 4.4 8.7 6.7 0.0 4.4 6 0 0 6 6 6 0 PQQ-like domain PCI PF01399.22 AEO61755.1 - 2.2e-20 72.9 0.6 8.4e-20 71.0 0.1 2.3 3 1 0 3 3 3 1 PCI domain TPR_8 PF13181.1 AEO61755.1 - 7.1e-06 25.4 7.9 4.4 7.3 0.0 5.5 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 AEO61755.1 - 8.6e-05 22.0 9.5 0.56 10.1 0.4 5.3 6 0 0 6 6 4 2 Tetratricopeptide repeat DDRGK PF09756.4 AEO61755.1 - 0.00023 20.6 0.2 0.00044 19.7 0.2 1.4 1 0 0 1 1 1 1 DDRGK domain TPR_16 PF13432.1 AEO61755.1 - 0.0024 18.4 18.9 1.2 9.9 0.3 5.0 5 1 0 5 5 4 2 Tetratricopeptide repeat SRPRB PF09439.5 AEO61755.1 - 0.052 12.7 0.2 0.1 11.8 0.1 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MetRS-N PF09635.5 AEO61755.1 - 0.058 13.7 2.1 5.5 7.4 0.2 2.9 2 1 0 2 2 2 0 MetRS-N binding domain PCI_Csn8 PF10075.4 AEO61755.1 - 0.07 12.9 0.8 0.17 11.6 0.5 1.6 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 TPR_1 PF00515.23 AEO61755.1 - 0.1 12.2 10.6 2.7 7.7 0.2 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat HTH_Crp_2 PF13545.1 AEO61755.1 - 0.16 11.8 1.5 0.52 10.1 0.2 2.6 3 1 0 3 3 3 0 Crp-like helix-turn-helix domain TPR_12 PF13424.1 AEO61755.1 - 0.32 10.9 21.5 0.057 13.3 0.7 5.4 3 2 3 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.1 AEO61755.1 - 0.39 11.4 16.6 17 6.3 0.1 6.9 6 1 0 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.12 AEO61755.1 - 0.45 10.5 14.8 7.3 6.7 0.0 5.8 5 2 1 6 6 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 AEO61755.1 - 0.51 10.9 0.1 0.51 10.9 0.1 4.3 6 0 0 6 6 3 0 Tetratricopeptide repeat AT_hook PF02178.14 AEO61756.1 - 0.28 11.0 20.7 0.77 9.6 2.7 3.9 2 0 0 2 2 2 0 AT hook motif Sds3 PF08598.6 AEO61758.1 - 6.8e-52 175.9 1.8 8.6e-52 175.6 1.2 1.3 1 0 0 1 1 1 1 Sds3-like AntA PF08346.7 AEO61758.1 - 0.019 15.1 0.5 0.045 13.9 0.4 1.6 1 0 0 1 1 1 0 AntA/AntB antirepressor Exonuc_VII_L PF02601.10 AEO61758.1 - 0.031 13.4 4.2 0.05 12.7 2.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Amidinotransf PF02274.12 AEO61758.1 - 0.045 12.8 0.0 0.083 11.9 0.0 1.4 1 0 0 1 1 1 0 Amidinotransferase LSM PF01423.17 AEO61759.1 - 4e-13 48.6 0.0 8.3e-13 47.6 0.0 1.5 2 0 0 2 2 2 1 LSM domain RecX PF02631.11 AEO61759.1 - 0.049 13.8 0.0 0.07 13.3 0.0 1.2 1 0 0 1 1 1 0 RecX family DUF3914 PF13053.1 AEO61760.1 - 0.22 11.7 0.0 0.46 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3914) Mob1_phocein PF03637.12 AEO61761.1 - 5.8e-70 234.5 0.0 7.2e-70 234.1 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family OSCP PF00213.13 AEO61762.1 - 6.3e-40 136.8 0.4 7.8e-40 136.5 0.3 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Glyco_hydro_63 PF03200.11 AEO61763.1 - 5.1e-08 31.2 1.8 2.6e-05 22.3 0.1 3.1 2 1 0 2 2 2 2 Mannosyl oligosaccharide glucosidase PP2C PF00481.16 AEO61764.1 - 1.3e-43 149.2 0.0 4e-43 147.6 0.0 1.7 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.1 AEO61764.1 - 0.00037 19.9 0.3 0.001 18.5 0.2 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 AEO61764.1 - 0.0037 16.9 0.1 0.65 9.6 0.0 2.8 3 0 0 3 3 3 1 Stage II sporulation protein E (SpoIIE) ComK PF06338.6 AEO61764.1 - 0.054 12.9 0.0 0.091 12.1 0.0 1.3 1 0 0 1 1 1 0 ComK protein SR-25 PF10500.4 AEO61765.1 - 0.05 13.0 4.8 0.066 12.6 3.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Molybdopterin PF00384.17 AEO61766.1 - 3.5e-77 259.9 0.0 2.7e-75 253.7 0.0 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.1 AEO61766.1 - 2.5e-19 68.8 0.2 7.7e-19 67.2 0.0 1.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.4 AEO61766.1 - 4.7e-19 67.3 0.1 1.3e-18 65.8 0.1 1.9 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF1982 PF09326.6 AEO61766.1 - 2.7e-15 56.2 0.0 7e-15 54.9 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 AEO61766.1 - 7.5e-09 35.2 0.4 7.5e-09 35.2 0.3 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.17 AEO61766.1 - 0.0003 20.5 0.0 0.013 15.2 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain DUF496 PF04363.7 AEO61767.1 - 0.0045 16.7 0.0 0.0099 15.6 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF496) Dabb PF07876.7 AEO61768.1 - 2.6e-26 91.8 0.0 3e-26 91.6 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain UBN2 PF14223.1 AEO61769.1 - 0.0027 17.4 0.1 0.0063 16.2 0.1 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type PolC_DP2 PF03833.8 AEO61769.1 - 0.012 13.3 1.6 0.018 12.7 1.1 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 UBN2_3 PF14244.1 AEO61769.1 - 0.05 13.1 0.3 0.13 11.8 0.0 1.9 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type DZR PF12773.2 AEO61769.1 - 0.75 9.6 7.6 1.4 8.7 5.3 1.4 1 0 0 1 1 1 0 Double zinc ribbon ACBP PF00887.14 AEO61770.1 - 1e-31 108.4 0.0 1.7e-31 107.7 0.0 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein M_domain PF12938.2 AEO61770.1 - 0.017 14.9 0.4 2.5 7.8 0.0 2.1 2 0 0 2 2 2 0 M domain of GW182 DUF4389 PF14333.1 AEO61770.1 - 0.021 14.4 0.3 0.037 13.7 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) PRT_C PF08372.5 AEO61770.1 - 0.12 11.8 0.7 0.18 11.3 0.1 1.5 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal Atg14 PF10186.4 AEO61770.1 - 0.12 11.2 1.1 0.91 8.4 0.4 2.0 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Ribonuclease_3 PF00636.21 AEO61771.1 - 7.7e-15 55.3 0.0 1.6e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 AEO61771.1 - 4.6e-12 46.0 0.0 1.3e-11 44.5 0.0 1.7 2 0 0 2 2 2 1 Ribonuclease-III-like dsrm PF00035.20 AEO61771.1 - 0.0088 16.5 0.2 0.034 14.7 0.1 2.0 1 1 0 1 1 1 1 Double-stranded RNA binding motif MRP-S33 PF08293.6 AEO61772.1 - 3e-23 81.5 0.0 3.5e-23 81.3 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 PUF PF00806.14 AEO61773.1 - 1.2e-40 134.6 0.5 2.5e-07 29.7 0.0 8.8 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat UPF0061 PF02696.9 AEO61774.1 - 2.5e-116 388.8 0.0 3.2e-116 388.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Aldo_ket_red PF00248.16 AEO61775.1 - 2e-48 164.6 0.0 2.7e-48 164.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family XRCC4 PF06632.7 AEO61776.1 - 2.6e-06 26.5 4.3 2.6e-06 26.5 3.0 1.9 1 1 1 2 2 2 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF3585 PF12130.3 AEO61776.1 - 0.00059 19.6 7.7 0.0011 18.8 5.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3585) HLH PF00010.21 AEO61776.1 - 0.00074 19.1 1.5 0.0079 15.8 0.2 2.6 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain LUC7 PF03194.10 AEO61776.1 - 0.0016 18.0 3.4 0.0022 17.6 2.4 1.3 1 0 0 1 1 1 1 LUC7 N_terminus DUF3584 PF12128.3 AEO61776.1 - 0.0035 14.7 4.0 0.0041 14.5 2.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF3573 PF12097.3 AEO61776.1 - 0.0071 15.0 0.2 0.01 14.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3573) IncA PF04156.9 AEO61776.1 - 0.082 12.4 7.0 0.17 11.4 4.9 1.5 1 0 0 1 1 1 0 IncA protein Atg14 PF10186.4 AEO61776.1 - 0.12 11.3 4.4 0.17 10.8 3.0 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 HalX PF08663.5 AEO61776.1 - 0.29 11.1 7.2 0.41 10.6 3.9 2.0 2 0 0 2 2 2 0 HalX domain DUF3864 PF12980.2 AEO61777.1 - 0.25 11.5 2.3 6.8 6.9 0.2 2.8 3 0 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3864) Glyco_hydro_3 PF00933.16 AEO61778.1 - 2.4e-43 148.2 0.0 2.8e-43 148.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Cofilin_ADF PF00241.15 AEO61779.1 - 1.8e-36 124.7 0.2 2.1e-36 124.5 0.1 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Cpn60_TCP1 PF00118.19 AEO61780.1 - 3.2e-115 385.5 9.6 3.6e-115 385.3 6.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family IER PF05760.7 AEO61781.1 - 0.065 13.1 2.6 0.063 13.2 1.8 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) CDC45 PF02724.9 AEO61781.1 - 1.4 6.8 5.2 1.5 6.7 3.6 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF4479 PF14794.1 AEO61784.1 - 0.15 11.6 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4479) ComJ PF11033.3 AEO61787.1 - 0.13 11.8 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 Competence protein J (ComJ) Tankyrase_bdg_C PF15327.1 AEO61788.1 - 0.054 13.6 0.1 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 Tankyrase binding protein C terminal domain DUF3246 PF11596.3 AEO61788.1 - 0.32 10.2 7.8 0.38 10.0 3.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) TFIIF_alpha PF05793.7 AEO61788.1 - 0.63 8.3 17.2 0.55 8.5 2.0 2.2 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SDA1 PF05285.7 AEO61788.1 - 1.3 8.2 14.0 3.3 6.9 9.8 1.5 1 1 0 1 1 1 0 SDA1 RNA_pol_Rpc4 PF05132.9 AEO61788.1 - 1.3 9.0 7.4 0.087 12.8 0.8 2.2 3 0 0 3 3 3 0 RNA polymerase III RPC4 DUF2457 PF10446.4 AEO61788.1 - 4.1 6.0 21.7 3.2 6.3 6.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) BMF PF15185.1 AEO61788.1 - 4.8 6.4 9.4 0.035 13.4 0.7 1.7 2 0 0 2 2 2 0 Bcl-2-modifying factor, apoptosis DUF1664 PF07889.7 AEO61790.1 - 0.001 18.8 25.9 0.011 15.4 0.1 5.7 3 2 4 7 7 7 3 Protein of unknown function (DUF1664) GP41 PF00517.12 AEO61790.1 - 0.0019 17.7 0.2 0.0019 17.7 0.2 3.0 4 0 0 4 4 4 1 Retroviral envelope protein Baculo_PEP_C PF04513.7 AEO61790.1 - 0.0022 17.8 20.7 0.23 11.2 1.1 4.7 1 1 3 4 4 4 4 Baculovirus polyhedron envelope protein, PEP, C terminus ApoO PF09769.4 AEO61790.1 - 0.057 13.1 3.9 0.46 10.1 0.3 2.9 2 0 0 2 2 2 0 Apolipoprotein O AIP3 PF03915.8 AEO61790.1 - 0.32 9.8 33.8 0.67 8.7 10.3 3.6 1 1 1 2 2 2 0 Actin interacting protein 3 D5_N PF08706.6 AEO61790.1 - 2.2 8.3 6.7 2.3 8.2 0.1 3.2 3 0 0 3 3 3 0 D5 N terminal like TIP49 PF06068.8 AEO61791.1 - 4.9e-175 582.0 3.4 5.8e-175 581.7 2.4 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 AEO61791.1 - 2.4e-08 34.2 0.3 2.3e-05 24.5 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 AEO61791.1 - 6.8e-08 31.8 2.2 2.5e-05 23.4 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus DnaB_C PF03796.10 AEO61791.1 - 1.4e-06 27.3 0.5 2.4e-06 26.6 0.3 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.1 AEO61791.1 - 0.00014 21.9 0.0 0.0014 18.6 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 AEO61791.1 - 0.00019 21.5 0.0 0.31 11.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 AEO61791.1 - 0.00092 18.4 0.9 0.015 14.4 0.3 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 AEO61791.1 - 0.0031 17.4 0.0 2 8.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 AEO61791.1 - 0.0083 15.6 0.1 2.7 7.4 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_25 PF13481.1 AEO61791.1 - 0.0091 15.4 0.1 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 AEO61791.1 - 0.011 15.4 0.2 2 8.1 0.0 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 AEO61791.1 - 0.026 14.2 1.0 0.086 12.6 0.3 2.2 1 1 1 2 2 2 0 Part of AAA domain AAA_28 PF13521.1 AEO61791.1 - 0.03 14.2 0.0 0.068 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 AEO61791.1 - 0.069 12.7 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 AEO61791.1 - 0.088 11.6 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 UFD1 PF03152.9 AEO61792.1 - 1.6e-61 206.4 0.0 2.1e-61 206.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 F-box-like PF12937.2 AEO61793.1 - 0.00011 21.8 0.0 0.00025 20.6 0.0 1.6 1 0 0 1 1 1 1 F-box-like VEFS-Box PF09733.4 AEO61794.1 - 1.2e-07 31.4 0.0 2.9e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 VEFS-Box of polycomb protein PHD PF00628.24 AEO61794.1 - 0.001 18.7 8.6 0.001 18.7 5.9 1.9 2 0 0 2 2 2 1 PHD-finger zf-C2H2_4 PF13894.1 AEO61794.1 - 9.5 6.8 6.9 0.65 10.4 0.1 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger DUF382 PF04037.8 AEO61795.1 - 9e-63 209.8 0.8 9e-63 209.8 0.6 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.11 AEO61795.1 - 2.7e-21 74.6 4.7 6.3e-21 73.4 3.3 1.7 1 0 0 1 1 1 1 PSP TPT PF03151.11 AEO61796.1 - 9.6e-39 132.4 2.2 1.1e-38 132.2 0.1 1.9 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 AEO61796.1 - 1.4e-12 47.1 3.5 2.7e-11 42.9 2.5 2.1 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 AEO61796.1 - 4.2e-05 23.5 28.2 0.00045 20.2 5.6 3.3 3 2 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.10 AEO61796.1 - 0.011 14.8 0.0 0.52 9.3 0.0 2.3 2 0 0 2 2 2 0 Nucleotide-sugar transporter Multi_Drug_Res PF00893.14 AEO61796.1 - 0.31 11.5 5.2 1.5 9.3 0.1 3.2 3 1 1 4 4 4 0 Small Multidrug Resistance protein ORC5_C PF14630.1 AEO61797.1 - 2e-74 250.4 0.0 1.2e-45 156.1 0.0 2.1 2 0 0 2 2 2 2 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 AEO61797.1 - 3.9e-15 56.3 0.8 1.5e-14 54.3 0.0 2.2 3 0 0 3 3 3 1 AAA ATPase domain Mito_fiss_reg PF05308.6 AEO61797.1 - 0.012 15.0 12.2 0.021 14.2 8.4 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator AAA_22 PF13401.1 AEO61797.1 - 0.033 14.3 0.0 0.089 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF3073 PF11273.3 AEO61797.1 - 0.038 14.5 5.1 0.088 13.3 3.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3073) DUF815 PF05673.8 AEO61797.1 - 0.16 10.8 0.0 0.27 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 AEO61797.1 - 0.27 10.8 0.0 0.37 10.4 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase DUF605 PF04652.11 AEO61797.1 - 6.4 6.0 10.5 9.7 5.4 7.3 1.2 1 0 0 1 1 1 0 Vta1 like Zn_clus PF00172.13 AEO61798.1 - 1.4e-07 31.3 10.1 2.3e-07 30.6 7.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 AEO61798.1 - 0.00015 20.4 0.0 0.00021 20.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Esterase_phd PF10503.4 AEO61799.1 - 9.8e-06 24.9 1.0 0.00038 19.7 1.2 2.2 1 1 1 2 2 2 1 Esterase PHB depolymerase Abhydrolase_5 PF12695.2 AEO61799.1 - 0.024 14.4 1.7 0.063 13.0 1.2 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family ATP-synt_ab PF00006.20 AEO61800.1 - 5.4e-62 209.0 0.0 8e-62 208.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 AEO61800.1 - 4.2e-26 91.6 0.5 8.2e-26 90.7 0.4 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 AEO61800.1 - 4e-25 87.8 0.5 3.2e-24 84.9 0.2 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA_25 PF13481.1 AEO61800.1 - 0.0061 15.9 0.1 0.043 13.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 AEO61800.1 - 0.0066 16.6 0.0 0.41 10.8 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 AEO61800.1 - 0.01 14.9 0.1 0.017 14.2 0.1 1.4 1 0 0 1 1 1 0 KaiC MobB PF03205.9 AEO61800.1 - 0.013 15.2 0.2 1 9.0 0.0 2.9 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 AEO61800.1 - 0.015 14.9 0.0 0.045 13.4 0.0 1.7 2 0 0 2 2 2 0 Archaeal ATPase DUF258 PF03193.11 AEO61800.1 - 0.02 14.1 0.1 0.036 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 AEO61800.1 - 0.024 14.2 0.1 0.065 12.8 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.1 AEO61800.1 - 0.032 14.3 0.0 0.13 12.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 AEO61800.1 - 0.035 14.0 0.5 0.3 11.0 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.17 AEO61800.1 - 0.053 13.7 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.17 AEO61800.1 - 0.12 11.2 1.0 0.56 9.0 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain Alpha-amylase_C PF02806.13 AEO61801.1 - 6.6e-24 83.8 0.0 1.9e-23 82.3 0.0 1.9 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 AEO61801.1 - 5.9e-20 71.8 0.0 3.5e-14 52.9 0.0 2.6 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 AEO61801.1 - 3.2e-15 55.9 0.0 7.1e-15 54.8 0.0 1.6 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Cellulase PF00150.13 AEO61801.1 - 0.085 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) hDGE_amylase PF14701.1 AEO61801.1 - 0.098 11.5 0.1 0.28 10.0 0.0 1.6 2 0 0 2 2 2 0 glucanotransferase domain of human glycogen debranching enzyme AAA_2 PF07724.9 AEO61802.1 - 5e-34 117.6 0.0 1.8e-33 115.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 AEO61802.1 - 5.6e-13 49.2 0.0 1.2e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 AEO61802.1 - 6.5e-09 35.5 0.0 1.3e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 AEO61802.1 - 6.4e-08 32.4 0.0 1.3e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 AEO61802.1 - 0.00021 21.2 0.0 0.00047 20.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AEO61802.1 - 0.00026 21.7 0.0 0.00072 20.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain MCM PF00493.18 AEO61802.1 - 0.00028 19.7 0.0 0.00051 18.9 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family AAA_22 PF13401.1 AEO61802.1 - 0.00067 19.7 0.7 0.0034 17.5 0.1 2.4 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 AEO61802.1 - 0.00099 19.1 0.1 0.046 13.6 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 AEO61802.1 - 0.002 17.5 0.0 0.0046 16.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.1 AEO61802.1 - 0.021 15.1 0.1 0.069 13.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain SOUL PF04832.7 AEO61802.1 - 0.043 13.3 0.0 0.074 12.5 0.0 1.3 1 0 0 1 1 1 0 SOUL heme-binding protein Mg_chelatase PF01078.16 AEO61802.1 - 0.049 12.7 0.0 1 8.4 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 AEO61802.1 - 0.05 13.8 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter T2SE PF00437.15 AEO61802.1 - 0.062 12.1 0.1 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein RPT PF13446.1 AEO61802.1 - 0.085 12.2 0.1 0.19 11.1 0.1 1.5 1 0 0 1 1 1 0 A repeated domain in UCH-protein AAA_29 PF13555.1 AEO61802.1 - 0.12 11.9 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ResIII PF04851.10 AEO61802.1 - 0.14 12.0 0.2 0.49 10.1 0.0 1.9 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_24 PF13479.1 AEO61802.1 - 0.16 11.5 0.1 0.33 10.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain WD40 PF00400.27 AEO61803.1 - 5.8e-42 140.1 13.8 1.7e-11 43.4 0.0 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 AEO61803.1 - 0.068 11.9 0.7 7 5.3 0.2 2.1 2 0 0 2 2 2 0 Coatomer WD associated region Mucin PF01456.12 AEO61803.1 - 0.075 12.8 37.4 0.18 11.5 25.9 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein Apc4_WD40 PF12894.2 AEO61803.1 - 0.091 12.2 0.0 1e+02 2.5 0.0 4.0 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Transket_pyr PF02779.19 AEO61804.1 - 5.4e-66 221.4 0.0 1e-65 220.5 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 AEO61804.1 - 2.4e-55 187.3 0.0 3.3e-55 186.9 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component TFIIH_BTF_p62_N PF08567.6 AEO61805.1 - 2.3e-25 88.0 0.0 5.6e-25 86.8 0.0 1.7 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain BSD PF03909.12 AEO61805.1 - 2.6e-25 87.9 2.2 9.6e-15 54.0 0.1 3.0 2 0 0 2 2 2 2 BSD domain AAA PF00004.24 AEO61806.1 - 4.1e-37 127.3 0.0 1.3e-36 125.7 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AEO61806.1 - 2.7e-05 24.3 0.5 0.0055 16.8 0.1 3.7 3 2 1 4 4 4 1 AAA domain RuvB_N PF05496.7 AEO61806.1 - 5.1e-05 22.4 0.0 9.3e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 AEO61806.1 - 7.3e-05 23.5 0.1 0.00064 20.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 AEO61806.1 - 0.0002 21.4 0.6 0.0002 21.4 0.4 4.3 3 1 0 3 3 3 1 AAA ATPase domain AAA_14 PF13173.1 AEO61806.1 - 0.00054 19.8 0.0 0.0019 18.0 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.1 AEO61806.1 - 0.00085 19.2 0.0 0.0029 17.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 AEO61806.1 - 0.002 17.6 0.0 0.0069 15.8 0.0 1.9 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 AEO61806.1 - 0.0042 16.8 2.6 0.016 14.9 0.1 3.1 3 0 0 3 3 3 1 Part of AAA domain AAA_5 PF07728.9 AEO61806.1 - 0.0096 15.6 0.0 0.022 14.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 AEO61806.1 - 0.01 14.5 0.0 0.016 13.9 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_18 PF13238.1 AEO61806.1 - 0.023 14.9 0.0 0.065 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 AEO61806.1 - 0.03 14.3 0.3 0.21 11.6 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 AEO61806.1 - 0.034 13.3 0.0 0.064 12.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.1 AEO61806.1 - 0.042 13.4 0.0 0.09 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 AEO61806.1 - 0.055 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.1 AEO61806.1 - 0.075 12.9 0.0 0.24 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 AEO61806.1 - 0.078 12.3 0.5 13 5.1 0.0 2.9 2 1 1 3 3 3 0 AAA-like domain AAA_24 PF13479.1 AEO61806.1 - 0.1 12.1 0.3 0.19 11.2 0.2 1.3 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 AEO61806.1 - 0.17 11.3 0.0 0.32 10.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Mus7 PF09462.5 AEO61807.1 - 3.3e-188 627.3 0.0 4.9e-188 626.8 0.0 1.3 1 0 0 1 1 1 1 Mus7/MMS22 family CorA PF01544.13 AEO61807.1 - 0.11 11.5 0.0 0.23 10.4 0.0 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein COX4 PF02936.9 AEO61808.1 - 2e-52 176.6 0.0 2.3e-52 176.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV PNPase_C PF12111.3 AEO61808.1 - 1.8 7.8 5.0 5.3 6.3 0.1 2.9 3 1 0 3 3 3 0 Polyribonucleotide phosphorylase C terminal DAO PF01266.19 AEO61809.1 - 3.8e-50 170.8 0.0 5.6e-50 170.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 AEO61809.1 - 3.7e-09 35.9 0.0 7.1e-09 34.9 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 AEO61809.1 - 4.9e-07 29.1 0.1 3.4e-05 23.0 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 AEO61809.1 - 0.00022 21.1 0.1 0.00052 19.9 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AEO61809.1 - 0.00076 19.4 0.1 0.0029 17.5 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 AEO61809.1 - 0.0039 16.8 0.1 0.0068 16.0 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 AEO61809.1 - 0.0063 15.6 0.4 0.035 13.1 0.2 2.0 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 AEO61809.1 - 0.0072 16.7 0.2 0.017 15.5 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 AEO61809.1 - 0.012 14.0 0.7 0.019 13.4 0.5 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.17 AEO61809.1 - 0.015 14.1 0.2 0.03 13.2 0.2 1.4 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 AEO61809.1 - 0.016 14.1 0.0 0.23 10.3 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_10 PF13460.1 AEO61809.1 - 0.031 14.2 0.3 0.08 12.9 0.1 1.8 2 0 0 2 2 2 0 NADH(P)-binding FAD_binding_3 PF01494.14 AEO61809.1 - 0.068 12.2 0.1 0.49 9.3 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.1 AEO61809.1 - 0.088 12.8 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.13 AEO61809.1 - 0.18 10.0 0.2 0.83 7.9 0.1 1.8 2 0 0 2 2 2 0 GDP dissociation inhibitor RGS PF00615.14 AEO61811.1 - 7.2e-11 42.2 0.0 1e-10 41.7 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain Peptidase_C48 PF02902.14 AEO61812.1 - 4.3e-14 52.6 0.0 8.1e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain FG-GAP PF01839.18 AEO61812.1 - 0.0083 15.8 2.0 0.018 14.7 1.4 1.5 1 0 0 1 1 1 1 FG-GAP repeat VCBS PF13517.1 AEO61812.1 - 0.34 11.2 2.1 0.8 10.1 1.5 1.6 1 0 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DDRGK PF09756.4 AEO61812.1 - 5.4 6.3 20.9 11 5.3 14.5 1.5 1 0 0 1 1 1 0 DDRGK domain Tox-ODYAM1 PF15642.1 AEO61812.1 - 9.1 4.8 8.1 14 4.2 5.6 1.2 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Cupin_8 PF13621.1 AEO61814.1 - 9.4e-40 136.6 0.0 1.8e-39 135.7 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain LCM PF04072.9 AEO61814.1 - 1.6e-18 66.8 0.2 1.4e-13 50.7 0.0 2.2 2 0 0 2 2 2 2 Leucine carboxyl methyltransferase Kelch_4 PF13418.1 AEO61814.1 - 8.1e-13 47.9 10.9 1.6e-09 37.3 0.0 4.0 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.1 AEO61814.1 - 1.8e-08 34.3 6.8 7.1e-07 29.2 0.0 4.2 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.1 AEO61814.1 - 3.9e-06 26.7 0.5 0.0016 18.5 0.0 3.3 2 1 1 3 3 3 1 Kelch motif Cupin_4 PF08007.7 AEO61814.1 - 0.0025 17.1 0.0 0.0062 15.8 0.0 1.6 1 0 0 1 1 1 1 Cupin superfamily protein Kelch_2 PF07646.10 AEO61814.1 - 0.0034 17.0 1.6 0.34 10.7 0.0 3.2 2 0 0 2 2 2 1 Kelch motif Kelch_1 PF01344.20 AEO61814.1 - 0.0088 15.5 0.0 0.075 12.5 0.0 2.6 2 0 0 2 2 2 1 Kelch motif Kelch_5 PF13854.1 AEO61814.1 - 0.014 15.3 0.2 6.9 6.7 0.0 3.5 3 0 0 3 3 3 0 Kelch motif Mito_carr PF00153.22 AEO61815.1 - 1.1e-46 156.4 10.8 6.6e-18 64.2 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein MFS_1 PF07690.11 AEO61816.1 - 1.7e-12 46.7 30.3 2.5e-08 33.0 14.2 2.7 2 1 1 3 3 3 3 Major Facilitator Superfamily Nodulin-like PF06813.8 AEO61816.1 - 6.9e-06 25.5 7.0 0.0037 16.5 0.4 3.2 3 0 0 3 3 3 2 Nodulin-like 7tm_7 PF08395.7 AEO61816.1 - 0.2 10.6 1.2 0.9 8.4 0.1 2.1 2 0 0 2 2 2 0 7tm Chemosensory receptor MFS_1 PF07690.11 AEO61817.1 - 3.4e-27 95.0 61.6 7e-21 74.3 18.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily RHS_repeat PF05593.9 AEO61818.1 - 4.7e-12 45.7 9.8 0.0005 20.1 0.1 5.6 5 0 0 5 5 5 3 RHS Repeat His_Phos_2 PF00328.17 AEO61819.1 - 0.00076 18.9 0.0 0.49 9.6 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) SKG6 PF08693.5 AEO61820.1 - 0.00071 18.8 0.1 0.0022 17.2 0.1 1.9 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4229 PF14012.1 AEO61820.1 - 0.0079 16.0 1.3 0.015 15.1 0.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4229) Rax2 PF12768.2 AEO61820.1 - 0.014 14.5 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity VPEP PF07589.6 AEO61820.1 - 4.9 7.1 9.7 4.1 7.4 5.3 2.0 1 1 1 2 2 2 0 PEP-CTERM motif LSM PF01423.17 AEO61821.1 - 8.1e-20 70.1 0.2 9.5e-20 69.9 0.1 1.1 1 0 0 1 1 1 1 LSM domain PRMT5 PF05185.11 AEO61822.1 - 9.4e-166 552.1 0.0 1.2e-165 551.8 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase OB_NTP_bind PF07717.11 AEO61823.1 - 1.3e-26 92.6 0.1 3.7e-26 91.1 0.1 1.8 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 AEO61823.1 - 7.8e-23 80.4 0.0 1.8e-22 79.2 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 AEO61823.1 - 2.9e-11 43.0 0.0 6.3e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 AEO61823.1 - 3e-08 33.8 0.1 8.1e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 AEO61823.1 - 7.2e-08 32.0 0.3 2.4e-07 30.3 0.2 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase SRP54 PF00448.17 AEO61823.1 - 0.00024 20.6 0.1 0.00074 19.0 0.1 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ResIII PF04851.10 AEO61823.1 - 0.002 18.0 0.1 0.42 10.4 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T2SE PF00437.15 AEO61823.1 - 0.0044 15.9 0.0 0.01 14.7 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein Response_reg PF00072.19 AEO61823.1 - 0.0097 15.8 0.5 0.22 11.5 0.1 2.8 3 0 0 3 3 3 1 Response regulator receiver domain AAA PF00004.24 AEO61823.1 - 0.028 14.6 0.8 0.31 11.2 0.1 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 AEO61823.1 - 0.042 13.8 0.0 0.099 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Flavi_DEAD PF07652.9 AEO61823.1 - 0.047 13.4 0.3 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 Flavivirus DEAD domain AAA_30 PF13604.1 AEO61823.1 - 0.08 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 AEO61823.1 - 0.14 12.4 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2435 PF10363.4 AEO61825.1 - 4.1e-18 65.0 0.9 1.1e-16 60.5 0.0 3.5 4 0 0 4 4 4 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 AEO61825.1 - 1e-13 50.4 0.5 3.3e-13 48.7 0.3 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2411) PHAT PF09246.5 AEO61825.1 - 0.065 12.8 0.1 7.6 6.1 0.0 2.5 2 0 0 2 2 2 0 PHAT Somatostatin PF03002.10 AEO61826.1 - 0.045 13.3 0.1 0.084 12.5 0.1 1.4 1 0 0 1 1 1 0 Somatostatin/Cortistatin family Pkinase PF00069.20 AEO61827.1 - 1.5e-05 24.3 0.0 1.9e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 AEO61828.1 - 0.012 14.7 0.0 0.012 14.7 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain DDHD PF02862.12 AEO61830.1 - 3.7e-37 128.3 0.0 2.7e-35 122.1 0.0 2.4 1 1 0 1 1 1 1 DDHD domain Abhydrolase_6 PF12697.2 AEO61830.1 - 0.018 14.9 0.0 0.018 14.9 0.0 2.8 2 1 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO61830.1 - 0.03 14.0 0.3 0.089 12.5 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF1227 PF06777.6 AEO61831.1 - 1.6e-62 209.5 0.2 3.8e-62 208.3 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 AEO61831.1 - 3e-51 173.2 0.4 5.6e-51 172.4 0.3 1.5 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 AEO61831.1 - 1e-43 149.1 0.0 3.1e-43 147.6 0.0 1.8 2 0 0 2 2 2 1 Helicase C-terminal domain SNF2_N PF00176.18 AEO61831.1 - 4.4e-05 22.4 0.0 0.00047 19.0 0.0 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 AEO61831.1 - 0.0018 17.8 0.0 0.43 10.0 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 AEO61831.1 - 0.0024 17.7 0.1 0.016 15.0 0.1 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_11 PF13086.1 AEO61831.1 - 0.0032 17.0 0.4 0.0079 15.7 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 AEO61831.1 - 0.024 14.3 0.0 0.087 12.5 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain zf-C2H2 PF00096.21 AEO61832.1 - 5.4e-14 51.6 19.6 7.8e-05 22.7 0.8 3.9 3 1 1 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AEO61832.1 - 3.9e-11 42.4 17.3 0.00056 20.0 0.4 3.9 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 AEO61832.1 - 0.00018 21.6 23.0 0.0011 19.1 1.5 4.5 4 1 1 5 5 5 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 AEO61832.1 - 0.0049 16.9 9.9 0.046 13.8 0.5 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 AEO61832.1 - 0.0062 16.1 0.5 0.017 14.7 0.3 1.8 1 0 0 1 1 1 1 zinc-finger of a C2HC-type zf-BED PF02892.10 AEO61832.1 - 0.16 11.7 9.1 1.6 8.5 2.8 3.0 2 1 1 3 3 3 0 BED zinc finger zf-C2H2_6 PF13912.1 AEO61832.1 - 0.5 10.3 7.9 0.16 11.8 1.3 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 AEO61832.1 - 0.72 9.9 8.8 4.9 7.3 4.8 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-TRAF PF02176.13 AEO61832.1 - 2 8.8 12.4 4 7.8 5.3 2.9 1 1 2 3 3 3 0 TRAF-type zinc finger PRP3 PF08572.5 AEO61833.1 - 1.2e-72 243.9 8.7 1.7e-72 243.4 6.0 1.2 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 AEO61833.1 - 6.8e-39 132.4 0.0 1.6e-38 131.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) RNA_pol_Rpb1_5 PF04998.12 AEO61834.1 - 1.8e-87 293.0 0.1 3.8e-87 292.0 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 AEO61834.1 - 1.4e-64 217.0 0.1 3.4e-64 215.7 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.7 AEO61834.1 - 3.2e-33 115.3 4.0 3.8e-22 79.0 0.0 3.1 2 1 1 3 3 3 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.13 AEO61834.1 - 8.1e-30 103.6 0.0 1.9e-29 102.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 AEO61834.1 - 4.1e-18 65.1 0.0 2.3e-17 62.7 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 DSBA PF01323.15 AEO61835.1 - 8.6e-20 71.1 0.0 1.4e-17 63.9 0.0 2.0 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Histone PF00125.19 AEO61836.1 - 3.6e-31 107.0 0.4 5.8e-31 106.4 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 AEO61836.1 - 4.1e-06 26.8 0.0 6.2e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 AEO61836.1 - 0.004 17.1 0.3 0.0074 16.3 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 AEO61836.1 - 0.014 15.1 0.1 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.19 AEO61837.1 - 1.3e-15 57.2 0.1 1.5e-15 57.0 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 AEO61837.1 - 8.7e-05 22.3 0.1 0.00013 21.8 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 AEO61837.1 - 8.9e-05 22.5 0.1 0.00012 22.1 0.0 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 AEO61837.1 - 0.00023 21.1 0.1 0.00044 20.2 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 AEO61837.1 - 0.0095 15.6 0.0 0.011 15.3 0.0 1.3 1 1 0 1 1 1 1 Bromodomain associated CENP-T PF15511.1 AEO61837.1 - 0.016 14.4 0.0 0.016 14.4 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 AEO61837.1 - 0.13 12.0 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Sugar_tr PF00083.19 AEO61839.1 - 1.9e-68 231.0 1.2 2.3e-68 230.8 0.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO61839.1 - 7.7e-12 44.5 11.1 1.9e-11 43.2 7.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 AEO61839.1 - 0.072 12.8 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 MFS_1 like family AA_permease PF00324.16 AEO61840.1 - 6.4e-133 443.5 39.5 7.9e-133 443.2 27.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 AEO61840.1 - 3.2e-38 131.3 44.4 4e-38 131.0 30.8 1.0 1 0 0 1 1 1 1 Amino acid permease ATP-synt_8 PF00895.15 AEO61840.1 - 4.3 7.6 5.9 4.4 7.5 0.1 3.2 3 0 0 3 3 3 0 ATP synthase protein 8 RVT_1 PF00078.22 AEO61841.1 - 4.6e-05 22.8 0.0 0.00011 21.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EPSP_synthase PF00275.15 AEO61842.1 - 2.6e-129 431.3 0.0 4.2e-129 430.6 0.0 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 AEO61842.1 - 6.2e-99 330.1 0.0 1.2e-98 329.2 0.0 1.5 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.10 AEO61842.1 - 4.5e-60 203.0 0.0 7.6e-60 202.3 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 AEO61842.1 - 3.8e-37 127.6 0.0 3.8e-35 121.1 0.0 2.3 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 AEO61842.1 - 1.3e-24 86.0 0.0 3.1e-24 84.8 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 AEO61842.1 - 6.8e-10 39.1 0.0 2.4e-09 37.3 0.0 1.9 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 AEO61842.1 - 2.1e-08 33.7 0.0 4.6e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 AEO61842.1 - 1.6e-05 25.6 0.0 4e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain zf-C2H2 PF00096.21 AEO61843.1 - 6.7e-09 35.5 15.1 0.016 15.5 0.9 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 AEO61843.1 - 0.0029 17.8 1.1 0.0029 17.8 0.8 4.7 5 0 0 5 5 5 3 C2H2-type zinc finger RasGAP PF00616.14 AEO61845.1 - 1.3e-46 158.7 0.0 3e-46 157.5 0.0 1.7 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.1 AEO61845.1 - 7.6e-07 29.1 0.1 2.1e-06 27.6 0.1 1.8 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Glyco_hydro_100 PF12899.2 AEO61845.1 - 0.17 10.2 0.0 0.32 9.3 0.0 1.3 1 0 0 1 1 1 0 Alkaline and neutral invertase XRN_N PF03159.13 AEO61846.1 - 6.8e-109 362.7 0.0 8.5e-109 362.4 0.0 1.1 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus Uso1_p115_head PF04869.9 AEO61847.1 - 5.9e-112 373.4 0.0 9.7e-112 372.7 0.0 1.4 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 AEO61847.1 - 2.4e-11 43.6 29.2 2.4e-11 43.6 20.3 3.4 1 1 0 3 3 3 1 Uso1 / p115 like vesicle tethering protein, C terminal region Tropomyosin PF00261.15 AEO61847.1 - 0.0021 17.1 37.7 0.0021 17.1 26.1 3.1 1 1 2 3 3 3 2 Tropomyosin HEAT PF02985.17 AEO61847.1 - 0.04 13.9 0.9 3.7 7.8 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat ADIP PF11559.3 AEO61847.1 - 0.18 11.6 45.7 0.4 10.5 3.8 4.1 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.7 AEO61847.1 - 1.2 8.2 7.4 21 4.1 0.0 2.9 2 1 0 2 2 2 0 Reovirus sigma C capsid protein IncA PF04156.9 AEO61847.1 - 3.1 7.3 58.4 0.22 11.1 10.9 4.2 1 1 3 4 4 4 0 IncA protein MscS_porin PF12795.2 AEO61847.1 - 5.3 6.2 54.9 0.082 12.2 3.0 3.3 1 1 2 3 3 3 0 Mechanosensitive ion channel porin domain Methyltransf_18 PF12847.2 AEO61848.1 - 1.4e-10 41.7 0.0 3.7e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 AEO61848.1 - 7e-09 35.2 0.0 1.5e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 AEO61848.1 - 1e-07 31.6 0.0 2.1e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 AEO61848.1 - 1.6e-07 31.7 0.0 5.4e-07 30.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO61848.1 - 2.8e-07 30.5 0.0 6.2e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO61848.1 - 4e-06 26.6 0.0 1e-05 25.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 AEO61848.1 - 1.3e-05 24.6 0.1 2.7e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 AEO61848.1 - 5.2e-05 23.6 0.0 0.00012 22.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO61848.1 - 0.00027 21.2 0.0 0.00061 20.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 AEO61848.1 - 0.0012 17.8 0.0 0.0023 16.9 0.0 1.4 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase CMAS PF02353.15 AEO61848.1 - 0.0014 17.7 0.0 0.0025 16.9 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.14 AEO61848.1 - 0.018 14.5 0.0 0.034 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.4 AEO61848.1 - 0.032 13.6 0.0 0.062 12.7 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_24 PF13578.1 AEO61848.1 - 0.045 14.5 0.0 0.17 12.7 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 AEO61848.1 - 0.065 13.2 0.1 0.15 12.0 0.0 1.5 2 0 0 2 2 1 0 FtsJ-like methyltransferase Methyltransf_9 PF08003.6 AEO61848.1 - 0.066 11.9 0.0 0.13 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Med21 PF11221.3 AEO61848.1 - 0.092 12.7 0.6 0.16 11.9 0.4 1.3 1 0 0 1 1 1 0 Subunit 21 of Mediator complex TehB PF03848.9 AEO61848.1 - 0.19 10.9 0.2 0.41 9.7 0.1 1.5 1 1 0 1 1 1 0 Tellurite resistance protein TehB DUF4407 PF14362.1 AEO61848.1 - 1.3 7.9 5.2 1.9 7.3 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) OPT PF03169.10 AEO61849.1 - 1.5e-150 502.6 22.4 2e-150 502.2 15.5 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4212 PF13937.1 AEO61849.1 - 1.8 8.6 14.0 0.083 12.9 0.5 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4212) Rav1p_C PF12234.3 AEO61850.1 - 9.9e-262 869.7 0.0 1.2e-261 869.4 0.0 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal DUF3712 PF12505.3 AEO61850.1 - 6.9e-07 29.3 0.5 2.1e-06 27.7 0.3 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) LEA_2 PF03168.8 AEO61850.1 - 0.00012 22.3 0.4 0.11 12.8 0.1 3.8 3 0 0 3 3 3 1 Late embryogenesis abundant protein WD40 PF00400.27 AEO61850.1 - 0.1 12.4 0.1 8.8 6.3 0.0 4.0 3 0 0 3 3 3 0 WD domain, G-beta repeat OTCace PF00185.19 AEO61851.1 - 2.4e-41 141.2 0.0 3.4e-41 140.7 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.16 AEO61851.1 - 1.5e-39 134.8 0.2 2.2e-39 134.3 0.1 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain HNF-1B_C PF04812.8 AEO61851.1 - 0.035 13.3 0.2 0.059 12.6 0.1 1.3 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus ALS_ss_C PF10369.4 AEO61852.1 - 4.4e-19 67.9 0.0 6.4e-18 64.2 0.0 2.4 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 AEO61852.1 - 3.5e-13 48.7 0.1 6.1e-13 47.9 0.1 1.4 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 AEO61852.1 - 1.2e-09 37.7 0.0 2.2e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.1 AEO61852.1 - 0.14 11.8 0.1 21 4.9 0.0 2.5 2 0 0 2 2 2 0 ACT domain DUF974 PF06159.8 AEO61853.1 - 2.5e-80 269.5 0.0 3.4e-80 269.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF974) KH_1 PF00013.24 AEO61853.1 - 3.2e-12 45.9 0.0 1.5e-08 34.1 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 AEO61853.1 - 3.8e-07 29.6 0.7 4.5e-05 23.0 0.0 2.9 2 0 0 2 2 2 1 KH domain Gryzun PF07919.7 AEO61853.1 - 0.0093 14.3 0.0 0.015 13.6 0.0 1.2 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Nucleoplasmin PF03066.10 AEO61853.1 - 0.013 15.0 3.1 0.024 14.1 2.1 1.4 1 0 0 1 1 1 0 Nucleoplasmin Ribosomal_60s PF00428.14 AEO61853.1 - 0.013 15.8 8.9 0.013 15.8 6.2 6.2 5 1 0 5 5 5 0 60s Acidic ribosomal protein Daxx PF03344.10 AEO61853.1 - 0.92 7.9 6.5 1.7 7.0 4.5 1.3 1 0 0 1 1 1 0 Daxx Family DENN PF02141.16 AEO61854.1 - 2.3e-57 193.7 0.0 4.4e-57 192.7 0.0 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.14 AEO61854.1 - 1.3e-17 63.5 0.1 2.4e-17 62.7 0.1 1.5 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.13 AEO61854.1 - 4.1e-17 61.8 0.0 8.3e-17 60.9 0.0 1.5 1 0 0 1 1 1 1 uDENN domain C1_1 PF00130.17 AEO61854.1 - 0.026 14.2 7.1 0.048 13.3 4.9 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SPA PF08616.5 AEO61854.1 - 0.083 12.6 0.1 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Stabilization of polarity axis Leader_CPA1 PF08252.6 AEO61854.1 - 0.15 11.3 0.5 0.37 10.0 0.3 1.6 1 0 0 1 1 1 0 arg-2/CPA1 leader peptide PHD PF00628.24 AEO61854.1 - 0.17 11.6 6.8 0.37 10.5 4.7 1.6 1 0 0 1 1 1 0 PHD-finger PPI_Ypi1 PF07491.6 AEO61855.1 - 7.3e-22 76.7 11.5 1.5e-20 72.5 8.0 2.5 1 1 0 1 1 1 1 Protein phosphatase inhibitor Cwf_Cwc_15 PF04889.7 AEO61855.1 - 0.084 12.5 7.8 0.14 11.8 5.3 1.6 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.9 AEO61855.1 - 0.58 8.1 10.3 0.83 7.6 7.1 1.3 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.7 AEO61855.1 - 0.92 7.8 12.3 1.5 7.1 8.5 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Dicty_REP PF05086.7 AEO61855.1 - 4.4 4.9 6.6 5.6 4.5 4.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Nucleo_P87 PF07267.6 AEO61855.1 - 5.7 5.4 5.6 8.5 4.9 3.9 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF726 PF05277.7 AEO61856.1 - 1.4e-96 323.3 0.3 4.5e-96 321.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF726) Glu-tRNAGln PF02686.10 AEO61857.1 - 7.3e-06 25.6 0.5 1.3e-05 24.9 0.2 1.5 2 0 0 2 2 2 1 Glu-tRNAGln amidotransferase C subunit TraG-D_C PF12696.2 AEO61857.1 - 0.09 12.6 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG SNAP PF14938.1 AEO61858.1 - 2.2e-104 348.5 18.1 2.5e-104 348.4 12.5 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 AEO61858.1 - 1e-08 35.0 13.4 0.00022 21.1 1.8 4.0 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 AEO61858.1 - 4e-07 29.4 18.8 0.16 11.9 0.1 6.5 3 1 4 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.1 AEO61858.1 - 0.00049 19.6 16.6 0.081 12.5 0.4 3.6 1 1 2 3 3 3 3 TPR repeat TPR_7 PF13176.1 AEO61858.1 - 0.00057 19.4 11.8 1.3 9.0 0.0 5.7 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 AEO61858.1 - 0.0021 18.7 15.8 0.027 15.1 0.0 3.6 1 1 2 3 3 3 1 Tetratricopeptide repeat NSF PF02071.15 AEO61858.1 - 0.0061 16.8 16.2 1.3 9.8 0.8 5.9 5 0 0 5 5 5 2 Aromatic-di-Alanine (AdAR) repeat TPR_8 PF13181.1 AEO61858.1 - 0.013 15.2 10.5 0.5 10.2 0.2 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 AEO61858.1 - 0.058 14.0 12.5 39 5.2 0.1 5.6 2 1 4 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 AEO61858.1 - 0.058 13.8 16.3 1.3 9.5 0.0 6.2 5 2 1 6 6 6 0 Tetratricopeptide repeat Spatacsin_C PF14649.1 AEO61858.1 - 1.2 7.9 5.1 3.9 6.2 0.6 2.2 1 1 1 2 2 2 0 Spatacsin C-terminus TPR_1 PF00515.23 AEO61858.1 - 1.9 8.2 14.4 8.3 6.2 0.7 5.1 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.4 AEO61858.1 - 2.4 8.0 13.3 0.1 12.5 1.6 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 AEO61858.1 - 5.2 7.2 9.2 2.6 8.2 2.2 3.2 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 NUC173 PF08161.7 AEO61859.1 - 1.4e-81 272.5 0.0 3.5e-78 261.5 0.0 3.5 3 0 0 3 3 3 2 NUC173 domain HEAT PF02985.17 AEO61859.1 - 0.019 14.9 1.7 13 6.1 0.0 4.1 5 0 0 5 5 5 0 HEAT repeat Amino_oxidase PF01593.19 AEO61860.1 - 1.9e-16 60.1 0.1 5e-13 48.9 0.0 2.9 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 AEO61860.1 - 1.9e-12 47.0 0.0 4.4e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 AEO61860.1 - 3.2e-07 29.6 1.9 0.00011 21.2 0.1 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 AEO61860.1 - 9.6e-07 29.0 0.1 0.0025 17.9 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 AEO61860.1 - 2e-06 27.6 0.5 0.028 14.1 0.1 3.0 3 1 0 3 3 3 2 FAD-NAD(P)-binding HI0933_like PF03486.9 AEO61860.1 - 3.4e-05 22.5 0.1 0.065 11.6 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.9 AEO61860.1 - 0.00018 21.4 0.0 0.0025 17.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 AEO61860.1 - 0.0021 18.4 0.2 0.56 10.6 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 AEO61860.1 - 0.0023 17.0 0.1 0.0038 16.3 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 AEO61860.1 - 0.0085 14.9 0.1 0.013 14.3 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 AEO61860.1 - 0.021 13.6 0.2 0.033 13.0 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.16 AEO61860.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain CtaG_Cox11 PF04442.9 AEO61861.1 - 2.8e-54 183.0 0.0 3.7e-54 182.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 MMR_HSR1 PF01926.18 AEO61862.1 - 0.00014 21.8 0.0 0.00039 20.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase L51_S25_CI-B8 PF05047.11 AEO61863.1 - 6.9e-20 70.5 0.0 1.6e-19 69.3 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain PMT PF02366.13 AEO61864.1 - 1.4e-79 266.9 16.1 1.4e-79 266.9 11.1 2.1 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 AEO61864.1 - 6.4e-36 123.6 0.1 1.2e-35 122.7 0.1 1.5 1 0 0 1 1 1 1 MIR domain DUF2976 PF11190.3 AEO61864.1 - 0.047 13.2 3.9 0.053 13.0 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) Ras PF00071.17 AEO61865.1 - 5.1e-48 162.5 0.0 3.4e-37 127.3 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 AEO61865.1 - 4.5e-16 59.4 0.0 6.2e-11 42.8 0.0 2.3 2 0 0 2 2 2 2 Miro-like protein Arf PF00025.16 AEO61865.1 - 2e-07 30.3 0.0 1.1e-06 28.0 0.0 2.0 3 0 0 3 3 3 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 AEO61865.1 - 1.2e-05 24.8 0.0 4.5e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 AEO61865.1 - 0.00013 21.8 0.0 0.00032 20.6 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 AEO61865.1 - 0.00028 20.0 0.0 0.00093 18.3 0.0 1.9 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 AEO61865.1 - 0.035 14.2 0.1 0.27 11.3 0.1 2.3 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 AEO61865.1 - 0.16 11.9 0.5 0.39 10.6 0.0 1.8 2 1 0 2 2 2 0 AAA ATPase domain DUF2360 PF10152.4 AEO61865.1 - 2.1 8.6 5.5 19 5.4 0.1 2.2 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Choline_transpo PF04515.7 AEO61866.1 - 5.9e-12 44.9 29.3 1.3e-10 40.5 14.5 2.8 3 0 0 3 3 3 2 Plasma-membrane choline transporter WW PF00397.21 AEO61867.1 - 0.00016 21.4 0.6 0.00034 20.4 0.4 1.6 1 0 0 1 1 1 1 WW domain DUF2012 PF09430.5 AEO61868.1 - 6.5e-23 80.8 0.0 1.1e-22 80.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) Mucin PF01456.12 AEO61868.1 - 0.76 9.5 23.3 1.3 8.7 16.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.6 AEO61868.1 - 4.4 5.1 19.0 6.5 4.5 13.2 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Cys_Met_Meta_PP PF01053.15 AEO61869.1 - 2.2e-150 500.2 0.0 2.5e-150 500.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 AEO61869.1 - 3.2e-12 46.1 0.3 7e-12 45.0 0.2 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 AEO61869.1 - 1.1e-08 34.2 0.2 2e-08 33.3 0.1 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 AEO61869.1 - 3e-08 33.0 0.1 5.2e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 AEO61869.1 - 7.7e-06 25.2 0.0 1.4e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.6 AEO61869.1 - 0.0016 16.8 0.1 0.0022 16.3 0.0 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.11 AEO61869.1 - 0.0076 14.9 0.0 0.013 14.2 0.0 1.3 1 0 0 1 1 1 1 Glycine cleavage system P-protein MARVEL PF01284.18 AEO61870.1 - 8.7e-14 51.5 19.6 1.8e-11 44.0 13.6 2.1 1 1 0 1 1 1 1 Membrane-associating domain DUF4229 PF14012.1 AEO61870.1 - 4.4 7.2 12.9 0.4 10.6 3.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) AMP-binding PF00501.23 AEO61871.1 - 6.3e-70 235.6 0.0 2.4e-68 230.4 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme WD40 PF00400.27 AEO61872.1 - 1.1e-05 25.1 11.1 0.088 12.7 0.1 5.2 6 0 0 6 6 6 3 WD domain, G-beta repeat RRM_1 PF00076.17 AEO61873.1 - 1.2e-07 31.2 0.0 2.2e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO61873.1 - 3.3e-07 30.0 0.1 6.7e-07 29.0 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO61873.1 - 1e-05 25.3 0.1 2.5e-05 24.1 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 AEO61873.1 - 0.0011 19.1 0.0 0.0039 17.3 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase II-binding domain. Citrate_synt PF00285.16 AEO61874.1 - 6.2e-106 354.1 0.0 7.7e-106 353.8 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Eclosion PF04736.7 AEO61874.1 - 0.009 15.4 0.0 0.023 14.1 0.0 1.6 1 0 0 1 1 1 1 Eclosion hormone Mito_carr PF00153.22 AEO61875.1 - 1.7e-29 101.3 4.8 2.7e-13 49.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein E1-E2_ATPase PF00122.15 AEO61877.1 - 6.3e-62 208.6 7.1 6.3e-62 208.6 4.9 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 AEO61877.1 - 4.3e-23 82.8 0.0 8.1e-23 81.9 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 AEO61877.1 - 4.9e-13 49.6 0.0 1.4e-12 48.1 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 AEO61877.1 - 2e-10 39.9 0.3 5.1e-10 38.6 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 AEO61877.1 - 0.0012 18.4 0.1 0.0028 17.2 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 AEO61877.1 - 0.013 15.4 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit FlgN PF05130.7 AEO61878.1 - 0.0051 17.0 1.4 0.0081 16.4 1.0 1.4 1 0 0 1 1 1 1 FlgN protein APG6 PF04111.7 AEO61878.1 - 0.0056 15.7 0.5 0.0069 15.4 0.3 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 OmpH PF03938.9 AEO61878.1 - 0.036 13.9 0.4 0.047 13.6 0.3 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1599 PF07659.6 AEO61878.1 - 0.086 12.9 2.6 5.7 7.0 0.1 2.3 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1599) DUF1664 PF07889.7 AEO61878.1 - 0.15 11.8 0.3 0.23 11.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Fzo_mitofusin PF04799.8 AEO61878.1 - 0.2 11.0 1.1 0.29 10.5 0.8 1.2 1 0 0 1 1 1 0 fzo-like conserved region DUF724 PF05266.9 AEO61878.1 - 0.22 11.1 3.0 0.61 9.6 2.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF724) CALCOCO1 PF07888.6 AEO61878.1 - 1.5 7.0 9.3 1.9 6.7 6.5 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2852 PF11014.3 AEO61878.1 - 2.5 8.0 6.2 2.6 8.0 3.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) DUF3425 PF11905.3 AEO61880.1 - 2.4e-22 79.2 0.6 2.4e-22 79.2 0.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) Nic96 PF04097.9 AEO61881.1 - 5.3e-222 738.2 0.0 6.9e-222 737.9 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 FGGY_C PF02782.11 AEO61881.1 - 8.9e-51 172.3 0.1 1.7e-50 171.4 0.1 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 AEO61881.1 - 1e-17 64.2 0.0 2.1e-16 59.9 0.0 2.6 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain SMN PF06003.7 AEO61882.1 - 1.9e-06 27.1 11.4 2.2e-05 23.7 0.1 3.0 1 1 2 3 3 3 2 Survival motor neuron protein (SMN) Sigma70_ner PF04546.8 AEO61882.1 - 0.16 11.6 3.0 0.19 11.3 2.1 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Cu_bind_like PF02298.12 AEO61883.1 - 0.036 13.8 0.1 0.16 11.7 0.1 2.0 1 1 0 1 1 1 0 Plastocyanin-like domain 4F5 PF04419.9 AEO61884.1 - 7.6e-11 42.5 8.8 7.6e-11 42.5 6.1 1.9 1 1 1 2 2 2 1 4F5 protein family CTD_bind PF04818.8 AEO61886.1 - 0.0019 18.4 0.0 0.0035 17.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CFIA_Pcf11 PF11526.3 AEO61886.1 - 0.0019 18.3 0.1 0.0044 17.1 0.1 1.5 1 0 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 RRN7 PF11781.3 AEO61886.1 - 0.026 13.9 3.4 0.29 10.6 0.7 2.5 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-C2H2_4 PF13894.1 AEO61886.1 - 0.18 12.1 2.0 9.1 6.8 0.3 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 AEO61886.1 - 0.28 10.9 4.2 2.2 8.0 0.6 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Aldo_ket_red PF00248.16 AEO61887.1 - 2.5e-18 65.9 0.0 3.7e-08 32.5 0.0 2.6 2 1 0 2 2 2 2 Aldo/keto reductase family GFO_IDH_MocA PF01408.17 AEO61888.1 - 4.2e-20 72.4 0.2 8.6e-20 71.4 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 AEO61888.1 - 0.011 16.1 0.2 0.02 15.3 0.2 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain OpuAC PF04069.7 AEO61888.1 - 0.089 12.1 0.1 25 4.0 0.0 3.2 4 0 0 4 4 4 0 Substrate binding domain of ABC-type glycine betaine transport system Methyltransf_11 PF08241.7 AEO61889.1 - 7e-11 42.4 0.0 2.1e-10 40.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 AEO61889.1 - 1.1e-05 25.8 0.0 3.1e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 AEO61889.1 - 2.6e-05 24.5 0.0 5.7e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 AEO61889.1 - 5e-05 23.0 0.0 8.8e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 AEO61889.1 - 9.7e-05 22.9 0.1 0.00021 21.8 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 AEO61889.1 - 0.0011 18.6 0.0 0.04 13.5 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Myb_DNA-binding PF00249.26 AEO61890.1 - 6.8e-12 45.2 2.1 7.5e-09 35.5 0.0 2.5 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 AEO61890.1 - 2.6e-07 30.6 2.5 0.00016 21.6 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Plasmodium_Vir PF05795.6 AEO61890.1 - 0.22 10.6 0.8 0.32 10.1 0.6 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein TFIIA PF03153.8 AEO61890.1 - 0.26 11.1 13.9 0.48 10.2 9.7 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4551 PF15087.1 AEO61890.1 - 0.3 9.3 5.2 0.52 8.6 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) PAT1 PF09770.4 AEO61890.1 - 1 7.5 35.0 1.9 6.6 18.1 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 BAF1_ABF1 PF04684.8 AEO61890.1 - 1.1 8.0 12.1 1.5 7.5 8.4 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF4557 PF15101.1 AEO61890.1 - 6.5 6.5 9.6 12 5.7 6.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) CAP_GLY PF01302.20 AEO61891.1 - 2.3e-22 78.4 2.5 3.3e-22 77.9 1.8 1.2 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 AEO61891.1 - 3.7e-19 68.7 0.0 5.7e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 AEO61891.1 - 6.6e-05 22.2 0.0 0.00013 21.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family zf-RING_2 PF13639.1 AEO61892.1 - 2e-14 53.1 4.7 3.3e-14 52.4 3.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 AEO61892.1 - 1.6e-07 30.8 3.3 2.8e-07 30.0 2.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 AEO61892.1 - 7e-07 29.2 1.1 1.4e-06 28.3 0.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 AEO61892.1 - 1.9e-06 27.7 5.6 3.2e-06 27.0 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO61892.1 - 2.6e-05 23.8 1.7 5.2e-05 22.8 1.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 AEO61892.1 - 0.00023 20.7 1.8 0.00044 19.8 1.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 AEO61892.1 - 0.0014 18.4 0.7 0.003 17.3 0.5 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Macoilin PF09726.4 AEO61892.1 - 0.013 13.7 11.8 0.017 13.4 8.2 1.1 1 0 0 1 1 1 0 Transmembrane protein CAF-1_p150 PF11600.3 AEO61892.1 - 0.019 14.3 26.2 0.03 13.7 18.2 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal zf-RING_4 PF14570.1 AEO61892.1 - 0.056 13.0 2.7 0.097 12.2 1.9 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain TFIIA PF03153.8 AEO61892.1 - 0.14 12.0 21.5 0.27 11.0 14.9 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SprA-related PF12118.3 AEO61892.1 - 0.43 9.8 35.6 0.7 9.1 24.7 1.2 1 0 0 1 1 1 0 SprA-related family FYDLN_acid PF09538.5 AEO61892.1 - 0.61 10.6 7.6 5.1 7.7 2.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) tRNA_synt_1c_R2 PF04557.10 AEO61892.1 - 1.3 9.7 8.9 0.12 13.0 1.6 2.4 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 DUF966 PF06136.8 AEO61892.1 - 1.7 8.0 22.2 2.5 7.4 15.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) zf-C3HC4_4 PF15227.1 AEO61892.1 - 3.7 7.5 6.2 7.5 6.5 4.3 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RR_TM4-6 PF06459.7 AEO61892.1 - 4 7.2 13.4 8.9 6.1 9.3 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SPX PF03105.14 AEO61892.1 - 9.5 5.8 25.7 1.8e+02 1.7 18.3 2.0 1 1 0 1 1 1 0 SPX domain Glyco_hydro_cc PF11790.3 AEO61893.1 - 1.1e-58 198.4 0.1 1.5e-58 198.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Macoilin PF09726.4 AEO61893.1 - 0.21 9.8 0.9 11 4.1 1.4 2.0 2 0 0 2 2 2 0 Transmembrane protein Fungal_trans_2 PF11951.3 AEO61894.1 - 0.017 13.7 0.1 0.025 13.2 0.1 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Chorion_2 PF03964.10 AEO61895.1 - 0.12 12.9 11.0 1.3 9.6 1.8 2.7 2 0 0 2 2 2 0 Chorion family 2 DUF3446 PF11928.3 AEO61895.1 - 4.6 7.5 24.3 2 8.6 0.7 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3446) 6PF2K PF01591.13 AEO61896.1 - 3.6e-69 232.2 0.0 1.4e-48 164.9 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 AEO61896.1 - 2.8e-27 95.7 0.1 7e-27 94.4 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 AEO61896.1 - 3.2e-05 23.8 0.0 0.00022 21.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 AEO61896.1 - 0.03 15.1 0.1 0.14 12.9 0.0 2.3 2 1 0 2 2 2 0 AAA domain KTI12 PF08433.5 AEO61896.1 - 0.057 12.6 0.0 0.097 11.8 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 PhoU PF01895.14 AEO61896.1 - 0.092 13.1 0.5 0.22 11.9 0.1 1.8 2 0 0 2 2 2 0 PhoU domain Sigma70_r4_2 PF08281.7 AEO61896.1 - 0.16 11.4 0.3 2.4 7.6 0.1 2.3 2 0 0 2 2 2 0 Sigma-70, region 4 Auxin_repressed PF05564.7 AEO61897.1 - 0.043 14.4 0.2 0.048 14.2 0.1 1.1 1 0 0 1 1 1 0 Dormancy/auxin associated protein WAK_assoc PF14380.1 AEO61897.1 - 0.058 13.8 0.0 0.075 13.5 0.0 1.2 1 1 0 1 1 1 0 Wall-associated receptor kinase C-terminal dCMP_cyt_deam_1 PF00383.17 AEO61899.1 - 4.3e-10 39.1 0.1 7.4e-10 38.3 0.1 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 AEO61899.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase Na_H_Exchanger PF00999.16 AEO61900.1 - 2e-40 138.5 19.3 2.7e-40 138.0 13.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Ank_2 PF12796.2 AEO61901.1 - 4.9e-16 58.8 0.1 1.1e-15 57.7 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 AEO61901.1 - 7.4e-16 57.0 2.3 2.8e-09 36.3 0.2 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 AEO61901.1 - 8.7e-15 54.4 0.8 3.8e-12 46.0 0.3 3.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 AEO61901.1 - 2.3e-12 47.0 1.7 4.8e-07 30.1 0.2 2.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 AEO61901.1 - 4.6e-11 41.8 0.7 9.9e-07 28.4 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeat TIG PF01833.19 AEO61901.1 - 2.3e-09 37.1 0.0 8e-09 35.3 0.0 1.9 1 0 0 1 1 1 1 IPT/TIG domain Peptidase_C97 PF05903.9 AEO61903.1 - 6.6e-07 29.2 0.0 8.5e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 AEO61903.1 - 0.0016 18.4 0.0 0.0035 17.2 0.0 1.6 2 0 0 2 2 2 1 Lecithin retinol acyltransferase DUF778 PF05608.7 AEO61903.1 - 0.025 14.5 0.1 0.043 13.7 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF778) Velvet PF11754.3 AEO61904.1 - 3.7e-65 219.3 0.0 5.8e-65 218.7 0.0 1.3 1 0 0 1 1 1 1 Velvet factor SelP_N PF04592.9 AEO61905.1 - 7.3 5.8 4.9 1.2 8.4 0.7 1.5 2 0 0 2 2 2 0 Selenoprotein P, N terminal region VTC PF09359.5 AEO61906.1 - 2.1e-93 312.4 0.0 4.7e-93 311.2 0.0 1.5 2 0 0 2 2 2 1 VTC domain SPX PF03105.14 AEO61906.1 - 1.4e-17 64.3 11.2 4e-13 49.7 7.7 3.4 1 1 0 1 1 1 1 SPX domain DUF202 PF02656.10 AEO61906.1 - 1.4e-07 31.5 8.1 1.4e-07 31.5 5.6 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Glu_synthase PF01645.12 AEO61907.1 - 9.9e-160 531.4 0.0 1.7e-159 530.6 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase GATase_2 PF00310.16 AEO61907.1 - 1.2e-140 468.3 0.0 1.6e-140 467.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 AEO61907.1 - 8.6e-121 402.6 0.1 7.6e-120 399.5 0.0 2.1 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.14 AEO61907.1 - 6e-68 227.8 2.4 1.1e-67 227.0 1.7 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 AEO61907.1 - 1.3e-22 79.4 0.1 3.5e-22 78.1 0.1 1.7 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 AEO61907.1 - 5.9e-18 65.4 0.0 2.5e-17 63.4 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 AEO61907.1 - 1.1e-11 45.2 0.2 2e-05 24.7 0.0 2.8 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AEO61907.1 - 6.6e-09 35.6 0.3 2.3e-08 33.9 0.0 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 AEO61907.1 - 1.4e-07 31.8 0.1 0.00016 22.0 0.0 3.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 AEO61907.1 - 4.1e-06 26.1 0.0 6.4e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 AEO61907.1 - 1.1e-05 24.5 0.2 6.3e-05 22.0 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 AEO61907.1 - 3.8e-05 22.3 0.1 3.8e-05 22.3 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_7 PF13241.1 AEO61907.1 - 4.6e-05 23.6 0.3 0.2 11.9 0.1 3.1 2 0 0 2 2 2 2 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 AEO61907.1 - 7.5e-05 22.3 0.2 0.003 17.1 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.19 AEO61907.1 - 0.00018 20.5 0.1 0.00054 18.9 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 AEO61907.1 - 0.00083 18.5 0.2 0.005 15.9 0.0 2.3 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 AEO61907.1 - 0.00091 18.3 0.0 0.0017 17.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 AEO61907.1 - 0.0023 17.1 0.0 0.005 15.9 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 AEO61907.1 - 0.0023 17.6 0.1 0.0067 16.1 0.0 1.8 2 0 0 2 2 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FMO-like PF00743.14 AEO61907.1 - 0.012 13.8 0.1 1.9 6.5 0.0 2.8 2 1 1 3 3 3 0 Flavin-binding monooxygenase-like Shikimate_DH PF01488.15 AEO61907.1 - 0.028 14.4 0.3 13 5.9 0.0 2.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 AEO61907.1 - 0.048 12.5 1.0 0.15 10.9 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A MADF_DNA_bdg PF10545.4 AEO61907.1 - 0.06 13.5 1.0 0.18 12.0 0.7 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DJ-1_PfpI PF01965.19 AEO61907.1 - 0.069 12.6 0.3 0.64 9.4 0.0 2.3 1 1 1 2 2 2 0 DJ-1/PfpI family NAD_binding_9 PF13454.1 AEO61907.1 - 0.088 12.5 0.0 0.27 11.0 0.0 1.9 1 0 0 1 1 1 0 FAD-NAD(P)-binding FMN_dh PF01070.13 AEO61907.1 - 0.095 11.5 0.9 0.33 9.7 0.6 1.9 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Lycopene_cycl PF05834.7 AEO61907.1 - 0.23 10.3 0.2 4.6 6.0 0.1 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein Histone_HNS PF00816.16 AEO61907.1 - 1.7 9.2 6.9 6.1 7.4 4.6 2.2 1 1 0 1 1 1 0 H-NS histone family Apc15p PF05841.6 AEO61908.1 - 2.7e-26 92.7 1.5 2.7e-26 92.7 1.0 2.6 2 1 0 2 2 2 1 Apc15p protein Daxx PF03344.10 AEO61908.1 - 6.1 5.2 27.0 8.2 4.7 18.7 1.2 1 0 0 1 1 1 0 Daxx Family SNARE PF05739.14 AEO61909.1 - 1.3e-08 34.4 2.7 1.8e-08 33.9 1.9 1.2 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.4 AEO61909.1 - 0.0099 15.3 0.0 0.0099 15.3 0.0 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 Dscam_C PF12355.3 AEO61909.1 - 0.14 12.3 3.1 0.21 11.8 2.1 1.3 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal CHZ PF09649.5 AEO61910.1 - 6.5e-16 57.2 0.6 2.3e-15 55.5 0.4 2.0 1 0 0 1 1 1 1 Histone chaperone domain CHZ Cyclin PF08613.6 AEO61911.1 - 2.5e-27 96.1 0.0 4.4e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 AEO61911.1 - 0.0029 17.1 0.0 0.0044 16.5 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Arm PF00514.18 AEO61912.1 - 3.5e-11 42.5 19.2 0.08 12.7 0.3 10.2 12 0 0 12 12 12 4 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 AEO61912.1 - 0.00069 20.0 24.8 0.22 12.0 0.2 7.8 7 0 0 7 7 7 2 HEAT-like repeat HEAT_2 PF13646.1 AEO61912.1 - 0.0062 16.7 0.2 0.0062 16.7 0.1 6.8 5 4 2 7 7 7 2 HEAT repeats V-ATPase_H_N PF03224.9 AEO61912.1 - 0.0098 15.0 0.0 0.88 8.6 0.0 3.2 3 1 0 3 3 3 1 V-ATPase subunit H HEAT PF02985.17 AEO61912.1 - 0.011 15.7 11.4 7.7 6.8 0.0 6.8 7 0 0 7 7 7 0 HEAT repeat Bac_rhodopsin PF01036.13 AEO61915.1 - 8.1e-32 110.3 28.8 1.1e-31 109.9 19.9 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein RRM_1 PF00076.17 AEO61917.1 - 6.9e-14 51.2 0.0 1.7e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 AEO61917.1 - 2.6e-12 46.5 0.0 5.3e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 AEO61917.1 - 3.7e-09 36.2 0.0 6.8e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GRAB PF10375.4 AEO61918.1 - 1.6e-08 33.8 0.0 3.1e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Filament PF00038.16 AEO61918.1 - 0.00091 18.7 56.6 0.0099 15.3 19.0 2.5 1 1 1 2 2 2 2 Intermediate filament protein Reo_sigmaC PF04582.7 AEO61918.1 - 0.0017 17.6 12.0 0.087 11.9 1.0 2.5 1 1 2 3 3 3 3 Reovirus sigma C capsid protein IFT57 PF10498.4 AEO61918.1 - 0.034 12.8 37.0 0.012 14.4 11.3 2.6 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 CENP-F_leu_zip PF10473.4 AEO61918.1 - 0.063 13.1 68.5 0.36 10.6 15.3 3.3 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Baculo_PEP_C PF04513.7 AEO61918.1 - 0.51 10.1 19.2 0.5 10.1 0.4 3.5 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4201 PF13870.1 AEO61918.1 - 0.78 9.1 46.6 0.12 11.8 12.5 3.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) Tropomyosin PF00261.15 AEO61918.1 - 1.1 8.2 68.5 1.3 8.0 9.7 3.2 1 1 2 3 3 3 0 Tropomyosin AAA_13 PF13166.1 AEO61918.1 - 1.4 7.2 39.7 1.2 7.5 16.2 2.4 1 1 1 2 2 2 0 AAA domain ApoO PF09769.4 AEO61918.1 - 1.5 8.5 14.2 12 5.6 0.3 3.9 1 1 3 4 4 4 0 Apolipoprotein O Bacillus_HBL PF05791.6 AEO61918.1 - 1.6 8.0 20.0 1.4 8.2 2.0 3.5 1 1 2 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) MAD PF05557.8 AEO61918.1 - 2.3 6.1 60.3 1.8 6.5 20.7 3.0 1 1 0 2 2 2 0 Mitotic checkpoint protein IncA PF04156.9 AEO61918.1 - 9.7 5.7 66.5 0.77 9.3 19.2 3.4 1 1 2 3 3 3 0 IncA protein Maf_N PF08383.6 AEO61919.1 - 0.00088 18.7 0.1 0.0035 16.8 0.0 2.1 1 1 1 2 2 2 1 Maf N-terminal region DUF1053 PF06327.9 AEO61919.1 - 0.16 12.3 0.1 0.26 11.6 0.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1053) CHD5 PF04420.9 AEO61920.1 - 6.9e-61 204.6 0.3 6.9e-61 204.6 0.2 1.3 2 0 0 2 2 2 1 CHD5-like protein PV-1 PF06637.6 AEO61920.1 - 0.056 12.0 0.0 0.062 11.8 0.0 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) PPTA PF01239.17 AEO61921.1 - 2.2e-06 26.7 7.2 0.018 14.3 0.3 3.7 5 0 0 5 5 5 2 Protein prenyltransferase alpha subunit repeat Asp PF00026.18 AEO61922.1 - 1.5e-67 228.1 1.5 1.8e-67 227.8 1.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 AEO61922.1 - 2.7e-09 37.1 0.3 8.2e-09 35.6 0.2 1.9 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 AEO61922.1 - 0.0084 15.6 0.0 0.032 13.7 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal RVP PF00077.15 AEO61922.1 - 0.14 12.0 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Aa_trans PF01490.13 AEO61923.1 - 3.9e-76 256.1 23.1 4.5e-76 255.9 16.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Zip PF02535.17 AEO61923.1 - 7.9 5.3 12.6 4.9 6.0 4.3 2.9 2 0 0 2 2 2 0 ZIP Zinc transporter DZR PF12773.2 AEO61924.1 - 0.00086 19.0 2.4 0.00086 19.0 1.7 1.4 1 1 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.1 AEO61924.1 - 0.014 14.8 3.4 0.029 13.8 2.4 1.6 1 0 0 1 1 1 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 AEO61924.1 - 0.048 12.8 6.5 0.048 12.8 4.5 2.2 1 1 1 2 2 2 0 zinc-ribbon domain RNA_POL_M_15KD PF02150.11 AEO61924.1 - 0.052 13.2 3.5 0.51 10.0 2.4 2.1 1 1 0 1 1 1 0 RNA polymerases M/15 Kd subunit zf-NADH-PPase PF09297.6 AEO61924.1 - 0.096 12.2 3.4 1.8 8.1 2.3 2.2 1 1 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain IR1-M PF12185.3 AEO61924.1 - 0.2 11.3 0.8 0.31 10.7 0.6 1.4 1 0 0 1 1 1 0 Nup358/RanBP2 E3 ligase domain TF_Zn_Ribbon PF08271.7 AEO61924.1 - 0.38 10.1 2.4 2.4 7.5 1.6 2.0 1 1 0 1 1 1 0 TFIIB zinc-binding Auto_anti-p27 PF06677.7 AEO61924.1 - 0.5 10.1 4.3 8.4 6.2 0.4 2.1 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-RanBP PF00641.13 AEO61924.1 - 0.73 8.9 4.1 3.6 6.7 2.8 1.9 1 1 0 1 1 1 0 Zn-finger in Ran binding protein and others zf-tcix PF14952.1 AEO61924.1 - 1 8.7 5.8 17 4.8 4.1 2.1 1 1 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding DUF35_N PF12172.3 AEO61924.1 - 3.2 7.7 4.9 19 5.3 0.2 2.3 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) OrfB_Zn_ribbon PF07282.6 AEO61924.1 - 3.4 7.4 5.4 6.6 6.4 0.4 2.0 1 1 1 2 2 2 0 Putative transposase DNA-binding domain PhnA_Zn_Ribbon PF08274.7 AEO61924.1 - 4.4 7.1 5.4 21 4.9 3.7 2.0 1 1 0 1 1 1 0 PhnA Zinc-Ribbon DUF1610 PF07754.6 AEO61924.1 - 6.7 6.9 8.5 8.6 6.5 1.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) Zn-ribbon_8 PF09723.5 AEO61924.1 - 9.5 6.2 7.3 4.8e+02 0.8 5.1 2.3 1 1 0 1 1 1 0 Zinc ribbon domain Ras PF00071.17 AEO61925.1 - 1.8e-55 186.7 0.0 2.1e-55 186.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 AEO61925.1 - 6e-14 52.5 0.0 1e-13 51.8 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 AEO61925.1 - 1.7e-06 27.3 0.0 3.2e-06 26.4 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 AEO61925.1 - 0.0006 19.0 0.0 0.0012 18.1 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 AEO61925.1 - 0.026 13.9 0.0 0.18 11.2 0.0 2.1 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 AEO61925.1 - 0.043 12.9 0.0 0.055 12.5 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region KOW PF00467.24 AEO61926.1 - 2.5e-06 26.9 1.2 5.6e-06 25.8 0.8 1.6 1 0 0 1 1 1 1 KOW motif YajC PF02699.10 AEO61926.1 - 0.038 13.6 0.7 0.11 12.1 0.5 1.8 1 0 0 1 1 1 0 Preprotein translocase subunit TMF_TATA_bd PF12325.3 AEO61928.1 - 0.00044 19.9 10.0 0.0011 18.6 0.5 2.8 3 0 0 3 3 3 2 TATA element modulatory factor 1 TATA binding End3 PF12761.2 AEO61928.1 - 0.02 14.5 1.2 3.2 7.3 0.0 2.6 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 TMF_DNA_bd PF12329.3 AEO61928.1 - 0.098 12.4 1.6 0.69 9.7 0.1 2.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Lebercilin PF15619.1 AEO61928.1 - 0.17 11.2 8.7 0.037 13.4 0.5 2.6 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease IncA PF04156.9 AEO61928.1 - 0.51 9.9 7.4 0.41 10.2 0.1 2.8 3 0 0 3 3 3 0 IncA protein GvpK PF05121.7 AEO61928.1 - 0.67 9.8 6.4 1.5 8.7 0.0 3.3 4 0 0 4 4 4 0 Gas vesicle protein K AKAP7_NLS PF10469.4 AEO61929.1 - 1.2e-19 70.8 0.0 2.6e-15 56.7 0.0 2.1 2 0 0 2 2 2 2 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.1 AEO61929.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 2'-5' RNA ligase superfamily Hpt PF01627.18 AEO61930.1 - 5.2e-12 45.5 0.1 1e-11 44.6 0.1 1.5 1 1 0 1 1 1 1 Hpt domain DUF3984 PF13136.1 AEO61931.1 - 9.2e-55 186.1 1.6 1.4e-54 185.5 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3984) PVL_ORF50 PF07768.6 AEO61931.1 - 1.2 9.1 3.6 2.2 8.3 2.5 1.3 1 0 0 1 1 1 0 PVL ORF-50-like family IKI3 PF04762.7 AEO61932.1 - 0 1083.2 0.0 0 1083.0 0.0 1.0 1 0 0 1 1 1 1 IKI3 family Clathrin PF00637.15 AEO61932.1 - 0.011 15.2 2.8 0.25 10.9 1.6 2.6 1 1 1 2 2 2 0 Region in Clathrin and VPS TPR_2 PF07719.12 AEO61932.1 - 0.046 13.6 2.4 0.28 11.2 0.3 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 AEO61932.1 - 0.37 10.4 4.7 0.11 12.1 0.3 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat HSP70 PF00012.15 AEO61933.1 - 1.6e-06 26.3 0.5 2.4e-05 22.4 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein Pkinase PF00069.20 AEO61934.1 - 2.9e-59 200.3 0.0 4.3e-59 199.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO61934.1 - 1.2e-31 109.7 0.0 3.1e-30 105.1 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 AEO61934.1 - 0.0072 15.1 0.0 0.01 14.6 0.0 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.18 AEO61935.1 - 0.089 12.5 1.7 0.2 11.3 1.2 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Stc1 PF12898.2 AEO61936.1 - 3.5e-16 59.0 2.4 3.5e-16 59.0 1.6 1.7 2 0 0 2 2 2 1 Stc1 domain Sugar_tr PF00083.19 AEO61938.1 - 1.3e-87 294.2 29.8 1.6e-87 293.9 20.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO61938.1 - 3.6e-20 71.9 23.4 3.6e-20 71.9 16.2 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Aminotran_1_2 PF00155.16 AEO61939.1 - 0.069 12.0 0.3 0.12 11.3 0.2 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II RCC1_2 PF13540.1 AEO61940.1 - 4.5e-18 64.3 12.7 5.5e-09 35.4 0.3 3.3 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 AEO61940.1 - 3.1e-11 43.2 4.7 0.0037 17.4 0.2 3.8 3 2 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat Proteasome PF00227.21 AEO61941.1 - 2.5e-56 189.9 0.0 2.1e-32 111.9 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 AEO61941.1 - 2.1e-11 42.9 0.3 4.3e-11 41.9 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature RINGv PF12906.2 AEO61942.1 - 3.4e-09 36.6 4.3 5.5e-09 35.9 0.7 2.2 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.1 AEO61942.1 - 0.012 15.4 1.3 0.012 15.4 0.9 2.1 2 0 0 2 2 2 0 Ring finger domain PHD PF00628.24 AEO61942.1 - 0.61 9.8 4.9 0.21 11.2 1.4 1.7 2 0 0 2 2 2 0 PHD-finger Glyco_transf_34 PF05637.7 AEO61943.1 - 3.9e-64 216.4 0.0 4.7e-64 216.1 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 AEO61943.1 - 0.0014 18.0 0.0 0.83 8.9 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function, DUF273 Pyridoxal_deC PF00282.14 AEO61944.1 - 5.9e-18 64.4 0.0 9.1e-18 63.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 AEO61944.1 - 3.2e-07 29.4 0.0 6.9e-07 28.3 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 AEO61944.1 - 0.011 14.7 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family DUF1775 PF07987.6 AEO61944.1 - 0.16 11.8 0.0 2.7 7.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unkown function (DUF1775) BCDHK_Adom3 PF10436.4 AEO61945.1 - 1.5e-70 235.9 0.0 2.2e-70 235.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 AEO61945.1 - 1.2e-17 63.6 0.0 3.6e-17 62.0 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 AEO61945.1 - 0.0074 15.9 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribonuclease_3 PF00636.21 AEO61946.1 - 3.4e-40 137.0 0.0 4.1e-21 75.5 0.0 3.0 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 AEO61946.1 - 2.7e-23 82.2 0.0 5.9e-11 42.4 0.0 3.7 3 0 0 3 3 3 3 Ribonuclease-III-like DEAD PF00270.24 AEO61946.1 - 3.6e-17 62.3 0.0 9.3e-17 61.0 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Dicer_dimer PF03368.9 AEO61946.1 - 3e-16 58.9 0.0 1.2e-15 57.0 0.0 2.1 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.26 AEO61946.1 - 4.2e-16 58.5 0.1 1.6e-15 56.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 AEO61946.1 - 2.3e-12 47.1 0.0 4.9e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit dsrm PF00035.20 AEO61946.1 - 7.1e-06 26.5 0.0 4.2e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 Double-stranded RNA binding motif DEAD_2 PF06733.10 AEO61946.1 - 0.1 12.0 0.1 0.25 10.7 0.1 1.6 1 0 0 1 1 1 0 DEAD_2 AAA_22 PF13401.1 AEO61946.1 - 0.16 12.1 0.0 0.54 10.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain Rgp1 PF08737.5 AEO61947.1 - 6e-118 394.5 0.0 9.7e-118 393.8 0.0 1.3 1 0 0 1 1 1 1 Rgp1 Arrestin_N PF00339.24 AEO61947.1 - 0.031 14.1 0.7 0.1 12.3 0.0 2.1 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain Glypican PF01153.14 AEO61947.1 - 5.4 5.4 5.5 0.58 8.6 0.1 1.8 2 0 0 2 2 2 0 Glypican LicD PF04991.8 AEO61948.1 - 2.1e-32 112.9 0.0 1.6e-14 54.5 1.1 2.6 1 1 1 2 2 2 2 LicD family DUF3827 PF12877.2 AEO61948.1 - 0.76 7.8 3.9 1 7.3 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) CDC45 PF02724.9 AEO61948.1 - 5 5.0 8.9 7.3 4.4 6.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Spt5_N PF11942.3 AEO61948.1 - 6.4 7.4 13.9 0.056 14.0 4.1 1.7 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DUF1180 PF06679.7 AEO61949.1 - 0.00032 20.6 0.8 0.00044 20.1 0.5 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1180) PAP2 PF01569.16 AEO61949.1 - 0.018 14.7 0.4 0.028 14.0 0.3 1.3 1 0 0 1 1 1 0 PAP2 superfamily Claudin_2 PF13903.1 AEO61949.1 - 0.15 11.7 0.1 0.15 11.7 0.1 2.0 1 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF4131 PF13567.1 AEO61949.1 - 0.86 8.9 3.5 6.5 6.1 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Arfaptin PF06456.8 AEO61950.1 - 0.02 14.2 4.1 0.039 13.3 2.9 1.5 1 0 0 1 1 1 0 Arfaptin-like domain Prominin PF05478.6 AEO61950.1 - 0.59 7.6 9.6 0.87 7.0 6.6 1.2 1 0 0 1 1 1 0 Prominin DUF972 PF06156.8 AEO61950.1 - 0.86 9.9 12.7 0.12 12.6 2.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF972) UPF0118 PF01594.11 AEO61950.1 - 0.95 8.3 4.3 1.2 8.0 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function DUF20 DUF1664 PF07889.7 AEO61950.1 - 2 8.2 6.1 2 8.2 2.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TBPIP PF07106.8 AEO61950.1 - 5.8 6.4 15.2 0.037 13.5 4.0 1.9 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ER_lumen_recept PF00810.13 AEO61951.1 - 4.2e-54 183.0 9.3 4.2e-54 183.0 6.4 1.4 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.9 AEO61951.1 - 0.048 13.2 12.3 0.067 12.7 0.1 3.8 5 0 0 5 5 5 0 PQ loop repeat Rep_fac_C PF08542.6 AEO61952.1 - 4.1e-24 84.3 0.1 1.8e-23 82.3 0.0 2.0 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 AEO61952.1 - 6.4e-12 45.4 0.0 1.2e-11 44.5 0.0 1.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 AEO61952.1 - 9.3e-07 29.1 0.1 2.2e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AEO61952.1 - 5.1e-06 26.6 0.8 0.00013 22.0 0.2 2.9 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 AEO61952.1 - 0.0001 22.3 2.1 0.027 14.4 0.6 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 AEO61952.1 - 0.0067 16.3 0.1 0.014 15.2 0.1 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 AEO61952.1 - 0.01 15.8 0.4 0.29 11.1 0.2 2.5 1 1 0 1 1 1 0 Sigma-54 interaction domain Rad17 PF03215.10 AEO61952.1 - 0.026 13.2 0.0 0.035 12.8 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein DUF2861 PF11060.3 AEO61952.1 - 0.027 13.8 0.1 0.057 12.7 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2861) T4SS-DNA_transf PF02534.9 AEO61952.1 - 0.032 12.8 0.1 0.11 11.0 0.0 1.7 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer SNF2_N PF00176.18 AEO61952.1 - 0.036 12.8 0.0 0.042 12.6 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_10 PF12846.2 AEO61952.1 - 0.037 13.4 0.2 1.3 8.4 0.0 2.5 2 1 0 3 3 3 0 AAA-like domain Arch_ATPase PF01637.13 AEO61952.1 - 0.042 13.5 0.0 0.1 12.3 0.0 1.7 1 1 0 1 1 1 0 Archaeal ATPase ABC_tran PF00005.22 AEO61952.1 - 0.065 13.5 0.0 0.17 12.1 0.0 1.6 1 1 0 1 1 1 0 ABC transporter Mg_chelatase PF01078.16 AEO61952.1 - 0.12 11.5 0.0 0.57 9.2 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 AEO61952.1 - 0.41 10.1 2.0 1.5 8.3 1.4 1.8 1 1 0 1 1 1 0 AAA domain Ribosomal_L16 PF00252.13 AEO61953.1 - 4.7e-30 104.0 0.2 6.7e-30 103.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e 5-FTHF_cyc-lig PF01812.15 AEO61953.1 - 0.089 12.5 0.1 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 5-formyltetrahydrofolate cyclo-ligase family RFC1 PF08519.7 AEO61954.1 - 4.2e-55 185.7 0.1 9.4e-55 184.6 0.0 1.6 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 AEO61954.1 - 1.4e-12 47.5 0.0 3.5e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 AEO61954.1 - 5.3e-09 36.3 0.0 1.6e-08 34.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 AEO61954.1 - 1.4e-06 27.3 0.0 2.4e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein DNA_pol3_delta PF06144.8 AEO61954.1 - 2.5e-05 23.8 0.0 4.9e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_17 PF13207.1 AEO61954.1 - 8.4e-05 23.3 0.1 8.4e-05 23.3 0.1 2.5 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.1 AEO61954.1 - 0.00033 20.8 0.0 0.0026 17.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 AEO61954.1 - 0.00047 20.4 0.1 0.0017 18.6 0.1 2.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AEO61954.1 - 0.0012 18.5 0.1 0.0029 17.3 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 AEO61954.1 - 0.011 15.7 0.0 0.051 13.5 0.0 2.1 1 1 1 2 2 2 0 AAA ATPase domain AAA_33 PF13671.1 AEO61954.1 - 0.015 15.1 0.0 0.04 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 AEO61954.1 - 0.018 14.9 2.9 0.021 14.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 AEO61954.1 - 0.021 14.7 0.0 0.048 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 AEO61954.1 - 0.021 13.8 0.0 0.039 13.0 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus NTPase_1 PF03266.10 AEO61954.1 - 0.021 14.5 0.1 0.068 12.8 0.0 1.9 2 0 0 2 2 2 0 NTPase NACHT PF05729.7 AEO61954.1 - 0.092 12.3 0.0 0.88 9.2 0.0 2.2 2 0 0 2 2 2 0 NACHT domain CytochromB561_N PF09786.4 AEO61954.1 - 0.17 10.2 3.2 0.37 9.1 2.2 1.5 1 0 0 1 1 1 0 Cytochrome B561, N terminal GAGA_bind PF06217.7 AEO61955.1 - 4.1 7.2 8.9 4.7 7.0 6.1 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family GrpE PF01025.14 AEO61956.1 - 2.6e-50 170.1 11.3 5.7e-50 169.1 7.8 1.6 1 1 0 1 1 1 1 GrpE YqfQ PF14181.1 AEO61956.1 - 0.0029 17.6 5.2 0.0098 15.9 3.7 1.7 2 0 0 2 2 2 1 YqfQ-like protein PfkB PF00294.19 AEO61956.1 - 0.013 14.6 0.1 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 pfkB family carbohydrate kinase SprA-related PF12118.3 AEO61956.1 - 0.06 12.6 9.5 0.092 12.0 6.6 1.2 1 0 0 1 1 1 0 SprA-related family CobT PF06213.7 AEO61956.1 - 0.13 11.3 8.6 0.11 11.5 3.8 2.0 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT MCLC PF05934.6 AEO61956.1 - 0.18 10.0 3.5 0.23 9.7 2.4 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Pox_RNA_Pol_19 PF05320.7 AEO61956.1 - 0.27 10.9 8.7 0.47 10.1 6.1 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit BTV_NS2 PF04514.7 AEO61956.1 - 0.56 9.0 7.4 0.71 8.6 5.1 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 IncA PF04156.9 AEO61956.1 - 1.5 8.3 6.0 1.9 8.0 4.2 1.3 1 0 0 1 1 1 0 IncA protein Presenilin PF01080.12 AEO61956.1 - 5.4 5.7 6.0 6.5 5.4 4.2 1.1 1 0 0 1 1 1 0 Presenilin RNA_pol_A_bac PF01000.21 AEO61957.1 - 6.2e-32 110.0 0.0 9.7e-32 109.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 AEO61957.1 - 4.2e-16 57.8 0.0 5.2e-16 57.5 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Mito_carr PF00153.22 AEO61958.1 - 3.5e-53 177.2 0.3 5.1e-18 64.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Arginosuc_synth PF00764.14 AEO61959.1 - 2e-143 478.1 0.0 2.3e-143 477.9 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 AEO61959.1 - 0.01 15.3 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase QueC PF06508.8 AEO61959.1 - 0.054 12.7 0.0 0.12 11.5 0.0 1.6 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC tRNA-synt_2d PF01409.15 AEO61960.1 - 8.7e-46 156.1 0.1 1.5e-22 79.9 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 AEO61960.1 - 7e-27 93.4 0.0 1.5e-26 92.3 0.0 1.6 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain Calcipressin PF04847.7 AEO61961.1 - 2.6e-53 180.3 0.3 3.5e-53 179.9 0.2 1.2 1 0 0 1 1 1 1 Calcipressin Neugrin PF06413.6 AEO61962.1 - 3e-12 46.8 1.0 3e-12 46.8 0.7 1.6 1 1 0 1 1 1 1 Neugrin MRP-L20 PF12824.2 AEO61962.1 - 1.1e-05 25.4 7.2 2.4e-05 24.3 5.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 HTH_29 PF13551.1 AEO61962.1 - 0.0091 16.1 1.1 0.089 12.9 0.0 2.6 2 0 0 2 2 2 1 Winged helix-turn helix DUF955 PF06114.8 AEO61962.1 - 0.054 13.2 0.0 0.089 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF955) YkuD PF03734.9 AEO61962.1 - 0.096 12.9 0.6 0.18 12.0 0.0 1.6 2 0 0 2 2 2 0 L,D-transpeptidase catalytic domain WD40 PF00400.27 AEO61963.1 - 4.6e-18 64.3 6.3 0.0002 21.1 0.0 7.6 7 0 0 7 7 7 4 WD domain, G-beta repeat WLM PF08325.5 AEO61964.1 - 7.6e-48 162.8 0.0 1.5e-47 161.8 0.0 1.4 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.12 AEO61964.1 - 0.00019 21.3 0.3 0.00019 21.3 0.2 1.5 2 0 0 2 2 2 1 Protein of unknown function DUF45 SprT-like PF10263.4 AEO61964.1 - 0.0085 15.7 0.2 0.013 15.1 0.1 1.4 1 1 0 1 1 1 1 SprT-like family Peptidase_MA_2 PF13485.1 AEO61964.1 - 0.064 13.3 0.8 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 Peptidase MA superfamily Reprolysin_5 PF13688.1 AEO61964.1 - 0.092 12.6 0.0 0.15 12.0 0.0 1.3 1 1 0 1 1 1 0 Metallo-peptidase family M12 Glyco_hydro_72 PF03198.9 AEO61965.1 - 3.5e-119 397.4 0.3 4.2e-119 397.1 0.2 1.0 1 0 0 1 1 1 1 Glucanosyltransferase ATP-grasp_2 PF08442.5 AEO61966.1 - 5.6e-08 32.4 0.0 9.1e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain CoA_binding PF02629.14 AEO61967.1 - 4e-19 68.9 0.1 1.4e-18 67.1 0.0 2.0 2 0 0 2 2 2 1 CoA binding domain Citrate_synt PF00285.16 AEO61967.1 - 4.1e-19 68.5 0.0 1.6e-16 59.9 0.0 2.9 1 1 1 2 2 2 2 Citrate synthase Ligase_CoA PF00549.14 AEO61967.1 - 5e-16 58.6 0.1 1.3e-15 57.2 0.0 1.7 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 AEO61967.1 - 2.3e-05 24.0 0.0 0.00052 19.6 0.0 2.4 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain Ribosomal_L30 PF00327.15 AEO61968.1 - 5e-16 58.0 0.1 6.4e-16 57.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e MRG PF05712.8 AEO61969.1 - 1.4e-57 193.8 0.1 2.1e-57 193.1 0.1 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 AEO61969.1 - 3.2e-07 29.9 0.6 6.4e-07 28.9 0.4 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 AEO61969.1 - 0.0043 16.6 0.8 0.013 15.1 0.6 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Cnl2_NKP2 PF09447.5 AEO61970.1 - 8.3e-29 99.0 1.6 1.5e-28 98.2 1.1 1.5 1 0 0 1 1 1 1 Cnl2/NKP2 family protein Ins_allergen_rp PF06757.8 AEO61970.1 - 0.054 12.9 0.0 0.081 12.4 0.0 1.2 1 0 0 1 1 1 0 Insect allergen related repeat, nitrile-specifier detoxification Ribosomal_60s PF00428.14 AEO61971.1 - 4 7.8 14.4 1.2e+02 3.1 0.0 2.8 2 1 0 2 2 2 0 60s Acidic ribosomal protein CENP-Q PF13094.1 AEO61972.1 - 3.1e-31 108.5 0.0 1.2e-30 106.6 0.0 2.0 2 1 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit Methyltransf_31 PF13847.1 AEO61973.1 - 3.7e-06 26.6 0.0 6.4e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 AEO61973.1 - 3.9e-06 25.8 0.0 0.00058 18.6 0.0 3.0 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase TRAM PF01938.15 AEO61973.1 - 2.8e-05 23.8 0.1 6e-05 22.7 0.1 1.5 1 0 0 1 1 1 1 TRAM domain PrmA PF06325.8 AEO61973.1 - 0.00013 21.2 0.0 0.00021 20.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 AEO61973.1 - 0.00049 20.6 0.0 0.0012 19.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 AEO61973.1 - 0.0024 17.9 0.2 0.0062 16.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain TRM PF02005.11 AEO61973.1 - 0.18 10.6 0.0 0.3 9.9 0.0 1.3 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase CAP_N PF01213.14 AEO61973.1 - 0.74 9.0 3.6 1.2 8.3 2.5 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SSP160 PF06933.6 AEO61973.1 - 1.7 6.5 9.3 2.6 5.9 6.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 TMEM171 PF15471.1 AEO61973.1 - 2.3 6.9 5.3 3.7 6.2 3.6 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 Glycos_transf_1 PF00534.15 AEO61974.1 - 3.7e-21 75.2 0.0 5.8e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 AEO61974.1 - 3.4e-12 46.6 0.1 9.5e-11 41.9 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 AEO61974.1 - 0.098 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase Family 4 60KD_IMP PF02096.15 AEO61975.1 - 2.2e-13 50.3 0.0 3e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein Syntaxin_2 PF14523.1 AEO61976.1 - 2.5e-26 91.6 1.3 2.5e-26 91.6 0.9 2.9 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 AEO61976.1 - 5.3e-19 67.6 3.6 1.5e-18 66.1 2.5 1.9 1 0 0 1 1 1 1 SNARE domain DUF883 PF05957.8 AEO61976.1 - 0.00044 20.6 9.4 1.3 9.5 0.9 3.4 2 1 1 3 3 3 2 Bacterial protein of unknown function (DUF883) MCPsignal PF00015.16 AEO61976.1 - 0.0042 16.6 7.8 0.016 14.7 0.9 2.2 2 0 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Synaptobrevin PF00957.16 AEO61976.1 - 0.0084 15.6 1.6 0.016 14.8 0.2 2.2 2 0 0 2 2 2 1 Synaptobrevin MMPL PF03176.10 AEO61976.1 - 0.022 13.4 2.1 0.074 11.7 0.2 2.1 2 0 0 2 2 2 0 MMPL family EspB PF05802.6 AEO61976.1 - 0.04 12.8 0.6 0.04 12.8 0.4 1.7 2 0 0 2 2 2 0 Enterobacterial EspB protein Vac_Fusion PF02346.11 AEO61976.1 - 0.054 12.9 0.0 0.2 11.1 0.0 2.0 1 0 0 1 1 1 0 Chordopoxvirus fusion protein DUF651 PF04895.7 AEO61976.1 - 0.085 12.4 0.6 0.83 9.3 0.1 2.4 2 0 0 2 2 2 0 Archaeal protein of unknown function (DUF651) ISG65-75 PF11727.3 AEO61976.1 - 0.16 10.9 3.6 0.81 8.6 0.3 2.1 2 0 0 2 2 2 0 Invariant surface glycoprotein K_channel_TID PF07941.6 AEO61976.1 - 0.22 11.7 5.2 0.55 10.4 3.6 1.6 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Prominin PF05478.6 AEO61976.1 - 0.4 8.1 3.8 0.24 8.9 0.1 1.9 2 0 0 2 2 2 0 Prominin DUF1664 PF07889.7 AEO61976.1 - 1.3 8.8 4.8 16 5.2 0.1 2.9 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) DUF4407 PF14362.1 AEO61976.1 - 3.1 6.6 14.2 4.7 6.0 9.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3708 PF12501.3 AEO61976.1 - 4.2 7.1 8.3 0.84 9.4 0.3 2.2 1 1 1 2 2 2 0 Phosphate ATP-binding cassette transporter T2SF PF00482.18 AEO61976.1 - 9.5 6.1 6.8 0.58 10.0 0.3 2.4 2 1 0 2 2 1 0 Type II secretion system (T2SS), protein F Ndc1_Nup PF09531.5 AEO61977.1 - 2.3e-159 531.6 0.0 2.5e-159 531.5 0.0 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Ribosomal_60s PF00428.14 AEO61977.1 - 1.3 9.4 5.4 0.42 11.0 1.3 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein HXXEE PF13787.1 AEO61977.1 - 1.4 9.2 6.4 0.16 12.3 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function with HXXEE motif DUF4129 PF13559.1 AEO61978.1 - 0.00034 20.5 0.7 0.00034 20.5 0.5 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4129) FA_desaturase PF00487.19 AEO61978.1 - 6.8 6.0 7.0 9.7 5.5 2.7 2.1 2 0 0 2 2 2 0 Fatty acid desaturase BAF1_ABF1 PF04684.8 AEO61979.1 - 0.75 8.5 5.3 1.3 7.7 3.6 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor FAD_binding_3 PF01494.14 AEO61980.1 - 1.3e-72 244.8 0.0 1.8e-72 244.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 AEO61980.1 - 9.2e-42 142.5 0.0 1.4e-41 141.8 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox PF00070.22 AEO61980.1 - 0.00022 21.5 0.0 0.0017 18.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 AEO61980.1 - 0.0098 15.8 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 AEO61980.1 - 0.013 14.4 0.0 0.023 13.6 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 AEO61980.1 - 0.015 15.1 0.0 0.035 13.9 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase XdhC_C PF13478.1 AEO61980.1 - 0.017 15.4 0.0 0.036 14.3 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain Thi4 PF01946.12 AEO61980.1 - 0.035 13.1 0.0 0.063 12.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 AEO61980.1 - 0.051 12.0 0.0 0.076 11.4 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein UDPG_MGDP_dh_N PF03721.9 AEO61980.1 - 0.098 12.0 0.0 0.31 10.4 0.0 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.16 AEO61980.1 - 0.11 12.2 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 ThiF family Fungal_trans PF04082.13 AEO61981.1 - 3.8e-25 88.2 0.1 1.1e-23 83.4 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO61981.1 - 4e-08 33.0 9.7 6.7e-08 32.3 6.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 AEO61982.1 - 3.9e-47 160.6 0.0 2.4e-23 82.4 0.0 3.1 2 1 1 3 3 3 3 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO61982.1 - 1.2e-05 25.0 6.8 2.3e-05 24.1 4.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3808 PF10300.4 AEO61982.1 - 0.055 12.0 0.0 0.078 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) EphA2_TM PF14575.1 AEO61983.1 - 0.07 13.5 0.1 0.13 12.6 0.1 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain HAMP PF00672.20 AEO61983.1 - 0.084 13.0 0.2 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 HAMP domain DUF1191 PF06697.7 AEO61983.1 - 0.11 11.3 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) HemY_N PF07219.8 AEO61983.1 - 0.13 11.8 0.2 0.3 10.6 0.1 1.5 1 0 0 1 1 1 0 HemY protein N-terminus TMEM154 PF15102.1 AEO61983.1 - 0.21 11.2 0.0 0.4 10.3 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family DUF605 PF04652.11 AEO61983.1 - 1.6 8.0 7.6 2.6 7.3 5.2 1.3 1 0 0 1 1 1 0 Vta1 like Abhydrolase_3 PF07859.8 AEO61984.1 - 9.9e-35 120.0 0.0 1.1e-23 83.9 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Lipase_3 PF01764.20 AEO61984.1 - 0.019 14.5 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2424 PF10340.4 AEO61984.1 - 0.26 9.8 0.0 0.41 9.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 AEO61985.1 - 2.5e-05 24.0 1.3 0.00064 19.4 0.9 3.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO61985.1 - 0.006 16.1 0.0 0.22 11.0 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 AEO61985.1 - 0.0062 16.1 7.2 0.84 9.1 0.1 3.5 3 2 1 4 4 4 2 alpha/beta hydrolase fold Fungal_trans PF04082.13 AEO61988.1 - 6.6e-28 97.2 0.0 1.1e-27 96.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 AEO61988.1 - 4.8e-08 32.7 12.5 8.9e-08 31.9 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Shugoshin_N PF07558.6 AEO61988.1 - 0.036 13.7 1.6 0.065 12.9 1.1 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Aminotran_3 PF00202.16 AEO61990.1 - 9.2e-93 310.7 0.0 1.2e-92 310.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III GAF PF01590.21 AEO61990.1 - 0.078 13.0 0.3 0.36 10.9 0.1 2.1 2 0 0 2 2 2 0 GAF domain Serglycin PF04360.7 AEO61991.1 - 0.0021 17.7 5.2 0.0021 17.7 3.6 3.4 2 1 1 3 3 3 3 Serglycin LsmAD PF06741.8 AEO61992.1 - 1.2e-22 79.7 2.2 1.2e-22 79.7 1.5 2.7 3 0 0 3 3 3 1 LsmAD domain SM-ATX PF14438.1 AEO61992.1 - 2.5e-06 27.3 0.0 5.9e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Ataxin 2 SM domain Tox-HDC PF15656.1 AEO61993.1 - 0.017 15.3 0.0 0.023 14.8 0.0 1.1 1 0 0 1 1 1 0 Toxin with a H, D/N and C signature Shisa PF13908.1 AEO61993.1 - 0.17 12.0 0.7 0.21 11.7 0.5 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator AIP3 PF03915.8 AEO61994.1 - 1.5e-166 554.5 6.3 2.3e-166 553.9 4.4 1.3 1 0 0 1 1 1 1 Actin interacting protein 3 Lectin_N PF03954.9 AEO61994.1 - 1.8e-05 24.1 0.2 9.4e-05 21.8 0.2 2.4 1 0 0 1 1 1 1 Hepatic lectin, N-terminal domain NPV_P10 PF05531.7 AEO61994.1 - 0.0024 18.0 5.4 0.037 14.2 0.2 3.8 2 1 1 3 3 3 1 Nucleopolyhedrovirus P10 protein Syntaxin_2 PF14523.1 AEO61994.1 - 0.0028 17.6 1.4 3.4 7.7 0.0 4.2 2 1 2 4 4 4 1 Syntaxin-like protein AKNA PF12443.3 AEO61994.1 - 0.0033 17.4 3.1 0.49 10.4 0.0 4.6 2 1 2 4 4 4 1 AT-hook-containing transcription factor DUF1664 PF07889.7 AEO61994.1 - 0.0055 16.4 4.7 0.07 12.9 0.2 3.3 2 1 1 3 3 3 1 Protein of unknown function (DUF1664) FliL PF03748.9 AEO61994.1 - 0.011 15.7 0.2 0.056 13.4 0.1 2.2 1 0 0 1 1 1 0 Flagellar basal body-associated protein FliL APG17 PF04108.7 AEO61994.1 - 0.011 14.6 1.3 3.3 6.4 0.0 3.2 3 0 0 3 3 3 0 Autophagy protein Apg17 TraF_2 PF13729.1 AEO61994.1 - 7.7 5.2 8.9 0.72 8.6 0.3 2.6 3 0 0 3 3 3 0 F plasmid transfer operon, TraF, protein Beta-lactamase PF00144.19 AEO61995.1 - 1.2e-38 132.9 0.4 1.6e-38 132.6 0.3 1.1 1 0 0 1 1 1 1 Beta-lactamase Myb_DNA-binding PF00249.26 AEO61996.1 - 1.3e-12 47.5 1.6 2.2e-05 24.3 0.0 3.7 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 AEO61996.1 - 0.0023 17.9 7.8 0.078 13.0 0.2 3.3 3 0 0 3 3 3 2 Myb-like DNA-binding domain DS PF01916.12 AEO61997.1 - 1.9e-147 490.1 0.0 2.2e-147 489.9 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase CmcH_NodU PF02543.10 AEO61997.1 - 0.057 12.5 0.0 0.099 11.7 0.0 1.3 1 0 0 1 1 1 0 Carbamoyltransferase HMGL-like PF00682.14 AEO61998.1 - 2.1e-40 138.8 0.0 8e-40 136.9 0.0 1.8 1 1 0 1 1 1 1 HMGL-like NACHT PF05729.7 AEO61999.1 - 4.2e-05 23.2 0.0 0.00012 21.7 0.0 1.8 1 0 0 1 1 1 1 NACHT domain PQQ_2 PF13360.1 AEO61999.1 - 0.0052 16.2 0.2 0.61 9.5 0.0 3.6 3 1 1 4 4 4 1 PQQ-like domain AAA_22 PF13401.1 AEO61999.1 - 0.11 12.6 0.0 0.47 10.5 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 AEO61999.1 - 0.12 11.8 0.0 1.7 7.9 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain Fructosamin_kin PF03881.9 AEO62000.1 - 3.6e-25 88.5 0.0 4.2e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 AEO62000.1 - 5.7e-08 32.7 0.0 7.6e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 AEO62000.1 - 0.0063 15.6 0.0 0.0092 15.1 0.0 1.3 1 1 0 1 1 1 1 Ecdysteroid kinase UPF0182 PF03699.8 AEO62001.1 - 0.11 10.3 0.1 0.13 10.2 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) MFS_1 PF07690.11 AEO62001.1 - 0.31 9.6 13.2 3.2 6.3 9.1 1.9 1 1 0 1 1 1 0 Major Facilitator Superfamily DUF3733 PF12534.3 AEO62001.1 - 4.4 6.6 6.5 7.4 5.9 4.5 1.3 1 0 0 1 1 1 0 Leucine-rich repeat containing protein 8 MFS_1 PF07690.11 AEO62002.1 - 7e-23 80.9 11.1 7e-23 80.9 7.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily HNH_2 PF13391.1 AEO62005.1 - 5e-10 39.0 0.0 1.3e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease Glyco_transf_90 PF05686.7 AEO62006.1 - 3.4e-07 29.3 0.0 2.8e-05 23.0 0.0 2.8 3 0 0 3 3 3 2 Glycosyl transferase family 90 Ank PF00023.25 AEO62007.1 - 2.7e-08 33.2 0.2 0.0049 16.6 0.1 3.9 3 1 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 AEO62007.1 - 3.5e-08 33.4 2.8 7.7e-05 22.8 0.5 4.2 5 0 0 5 5 5 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 AEO62007.1 - 3.7e-08 33.5 0.3 5.7e-06 26.5 0.0 3.2 3 1 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 AEO62007.1 - 0.00012 21.9 2.0 0.18 12.1 0.0 4.5 5 1 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.1 AEO62007.1 - 0.00016 22.1 1.1 1.6 9.2 0.0 4.8 5 1 2 7 7 7 2 Ankyrin repeats (many copies) Draxin PF15550.1 AEO62007.1 - 0.76 9.3 6.8 0.54 9.8 0.4 2.1 2 0 0 2 2 2 0 Draxin Mucin PF01456.12 AEO62007.1 - 2.2 8.0 30.5 0.044 13.5 15.1 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein Esterase_phd PF10503.4 AEO62008.1 - 2.7e-27 95.4 0.1 3.7e-27 95.0 0.1 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 AEO62008.1 - 2.6e-11 43.1 0.2 4.2e-11 42.4 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 AEO62008.1 - 4.3e-08 33.0 0.1 6.4e-08 32.4 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 AEO62008.1 - 1.1e-05 25.4 0.2 2.7e-05 24.1 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 AEO62008.1 - 0.00057 19.5 0.0 0.00073 19.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 AEO62008.1 - 0.016 14.6 0.4 0.046 13.1 0.3 1.7 1 1 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.11 AEO62008.1 - 0.039 13.4 0.2 0.18 11.2 0.2 2.2 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase DLH PF01738.13 AEO62008.1 - 0.072 12.3 0.1 0.15 11.3 0.1 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family SDA1 PF05285.7 AEO62009.1 - 1.9e-87 293.6 37.9 1.9e-87 293.6 26.3 2.1 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.7 AEO62009.1 - 7.4e-22 77.3 0.1 2e-21 75.9 0.1 1.8 1 0 0 1 1 1 1 NUC130/3NT domain bZIP_1 PF00170.16 AEO62010.1 - 2.1e-07 30.7 4.9 2.1e-07 30.7 3.4 2.9 3 0 0 3 3 3 1 bZIP transcription factor Neur_chan_memb PF02932.11 AEO62010.1 - 0.14 12.0 6.7 0.075 12.9 0.1 2.3 1 1 1 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Tyrosinase PF00264.15 AEO62011.1 - 9.8e-05 22.6 0.0 0.00017 21.8 0.0 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase DOCK-C2 PF14429.1 AEO62013.1 - 1.7e-22 79.9 0.0 2.8e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 AEO62013.1 - 9.5e-08 31.5 0.0 2.6e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Dedicator of cytokinesis SH3_1 PF00018.23 AEO62013.1 - 5.1e-05 22.5 0.0 0.00011 21.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 AEO62013.1 - 0.0013 18.2 0.0 0.0082 15.6 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain DUF4647 PF15504.1 AEO62013.1 - 0.39 9.5 0.0 0.64 8.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Sigma70_ner PF04546.8 AEO62014.1 - 0.011 15.4 0.4 0.011 15.4 0.3 1.4 2 0 0 2 2 2 0 Sigma-70, non-essential region SR-25 PF10500.4 AEO62014.1 - 0.077 12.4 5.4 0.13 11.7 3.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CN_hydrolase PF00795.17 AEO62017.1 - 2.5e-21 75.8 0.0 4.1e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase HATPase_c_3 PF13589.1 AEO62019.1 - 1.4e-15 57.1 0.0 5.1e-15 55.3 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 AEO62019.1 - 6.7e-11 41.9 0.0 6.1e-10 38.8 0.0 2.2 2 0 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c PF02518.21 AEO62019.1 - 9.1e-05 22.1 0.0 0.00029 20.5 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Clathrin PF00637.15 AEO62020.1 - 9.3e-25 86.8 7.2 1.3e-23 83.2 2.6 3.1 3 1 1 4 4 4 1 Region in Clathrin and VPS VPS11_C PF12451.3 AEO62020.1 - 9.8e-22 76.5 0.5 4e-21 74.5 0.2 2.2 2 0 0 2 2 2 1 Vacuolar protein sorting protein 11 C terminal zf-RING_2 PF13639.1 AEO62020.1 - 0.00035 20.3 1.3 0.0011 18.7 0.9 1.9 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 AEO62020.1 - 0.00068 19.3 1.3 0.0015 18.2 0.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain TPR_11 PF13414.1 AEO62020.1 - 0.0025 17.4 0.5 0.024 14.2 0.0 2.7 2 0 0 2 2 2 1 TPR repeat TPR_14 PF13428.1 AEO62020.1 - 0.023 15.3 0.0 23 5.9 0.0 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 AEO62020.1 - 0.11 12.9 2.6 14 6.0 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-C3HC4 PF00097.20 AEO62020.1 - 0.14 11.8 4.5 0.039 13.6 0.4 2.2 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TPR_12 PF13424.1 AEO62020.1 - 0.16 11.9 6.2 0.21 11.5 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 AEO62020.1 - 0.34 10.9 3.3 0.55 10.2 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-rbx1 PF12678.2 AEO62020.1 - 0.35 11.0 2.1 1.2 9.3 1.5 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 AEO62020.1 - 0.43 10.6 5.9 0.44 10.6 1.2 2.6 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TPR_8 PF13181.1 AEO62020.1 - 3.2 7.7 11.1 0.16 11.7 0.3 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Chorismate_synt PF01264.16 AEO62021.1 - 1.9e-127 424.5 0.0 3.8e-127 423.5 0.0 1.4 1 1 0 1 1 1 1 Chorismate synthase Phage_lysozyme PF00959.14 AEO62022.1 - 5.6e-14 52.3 0.0 9.1e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Phage lysozyme SH3_3 PF08239.6 AEO62022.1 - 0.0033 17.5 1.2 0.033 14.3 0.1 2.5 2 0 0 2 2 2 1 Bacterial SH3 domain CHAP PF05257.11 AEO62023.1 - 5.2e-21 74.6 8.2 5.2e-21 74.6 5.7 1.6 2 0 0 2 2 2 1 CHAP domain SH3_3 PF08239.6 AEO62023.1 - 0.0084 16.2 2.0 0.016 15.3 0.1 2.3 2 1 1 3 3 3 1 Bacterial SH3 domain p450 PF00067.17 AEO62025.1 - 1.1e-33 116.4 0.0 1.5e-33 116.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MerT PF02411.10 AEO62027.1 - 0.089 12.6 0.1 0.095 12.5 0.1 1.1 1 0 0 1 1 1 0 MerT mercuric transport protein Fungal_trans_2 PF11951.3 AEO62028.1 - 7.8e-08 31.3 0.0 1.1e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 AEO62029.1 - 2.8e-07 30.5 0.3 3.6e-07 30.2 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO62029.1 - 4.9e-05 23.0 0.1 6.9e-05 22.5 0.1 1.1 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 AEO62030.1 - 2.3e-18 66.6 2.3 3.8e-18 65.9 1.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO62030.1 - 5.3e-12 45.7 1.3 1.1e-11 44.6 0.9 1.5 1 0 0 1 1 1 1 KR domain DUF162 PF02589.10 AEO62030.1 - 0.16 11.4 1.0 0.29 10.6 0.7 1.4 1 0 0 1 1 1 0 Uncharacterised ACR, YkgG family COG1556 Glyco_trans_4_4 PF13579.1 AEO62030.1 - 0.43 10.7 6.2 1.1 9.3 4.0 2.1 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain Frataxin_Cyay PF01491.11 AEO62031.1 - 1.4e-33 114.9 0.0 1.8e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain Clat_adaptor_s PF01217.15 AEO62032.1 - 4.5e-43 146.3 0.0 8.7e-43 145.4 0.0 1.4 1 1 0 1 1 1 1 Clathrin adaptor complex small chain BESS PF02944.15 AEO62033.1 - 0.0086 15.6 0.4 0.024 14.1 0.3 1.8 1 0 0 1 1 1 1 BESS motif DUF3377 PF11857.3 AEO62033.1 - 0.043 13.4 0.1 0.079 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) tRNA-synt_1 PF00133.17 AEO62034.1 - 4.5e-40 137.2 0.0 4.5e-30 104.2 0.0 3.1 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 AEO62034.1 - 2.1e-19 69.4 0.0 8.3e-12 44.4 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 AEO62034.1 - 1.6e-12 47.4 1.2 4.1e-12 46.1 0.8 1.8 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 AEO62034.1 - 4.5e-08 32.5 0.0 1.2e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.1 AEO62034.1 - 0.34 10.2 0.0 0.34 10.2 0.0 2.8 4 0 0 4 4 4 0 Leucyl-tRNA synthetase, Domain 2 zf-CSL PF05207.8 AEO62035.1 - 1.3e-24 85.4 2.1 1.6e-24 85.1 1.4 1.1 1 0 0 1 1 1 1 CSL zinc finger EF-hand_4 PF12763.2 AEO62036.1 - 6.9e-33 112.4 0.0 5.3e-13 48.5 0.0 3.5 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 AEO62036.1 - 6.8e-11 42.1 0.0 2.9e-06 27.3 0.1 3.7 3 1 1 4 4 4 2 EF-hand domain pair UBA PF00627.26 AEO62036.1 - 1.5e-07 31.0 0.4 3.7e-07 29.7 0.0 1.9 2 0 0 2 2 1 1 UBA/TS-N domain EF-hand_1 PF00036.27 AEO62036.1 - 2e-07 29.8 0.2 0.16 11.3 0.0 4.7 4 0 0 4 4 4 1 EF hand EF-hand_6 PF13405.1 AEO62036.1 - 6.4e-06 25.6 0.2 1.7 8.7 0.0 5.3 5 0 0 5 5 5 1 EF-hand domain Macoilin PF09726.4 AEO62036.1 - 0.00023 19.5 19.8 0.00023 19.5 13.7 3.5 2 1 0 3 3 1 1 Transmembrane protein EF-hand_8 PF13833.1 AEO62036.1 - 0.0018 17.8 0.1 0.79 9.3 0.0 3.8 3 1 1 4 4 4 1 EF-hand domain pair AAA_27 PF13514.1 AEO62036.1 - 0.011 13.4 27.1 0.019 12.7 18.8 1.3 1 0 0 1 1 1 0 AAA domain MAD PF05557.8 AEO62036.1 - 0.015 13.4 23.5 0.022 12.8 16.3 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein IncA PF04156.9 AEO62036.1 - 0.1 12.2 34.8 0.0098 15.5 11.8 2.3 1 1 1 2 2 2 0 IncA protein ADIP PF11559.3 AEO62036.1 - 0.16 11.8 42.9 0.15 11.9 8.7 3.6 2 1 2 4 4 3 0 Afadin- and alpha -actinin-Binding GAS PF13851.1 AEO62036.1 - 0.26 10.4 37.0 0.57 9.3 15.5 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 AEO62036.1 - 0.28 11.0 34.5 0.18 11.6 10.5 2.8 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.7 AEO62036.1 - 0.64 9.7 41.4 1.8 8.3 5.7 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein CENP-Q PF13094.1 AEO62036.1 - 0.72 9.8 42.6 0.014 15.4 9.6 3.5 1 1 2 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF1664 PF07889.7 AEO62036.1 - 0.76 9.5 16.1 0.15 11.8 4.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.6 AEO62036.1 - 1.1 7.8 32.7 1.9 7.0 6.7 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein WEMBL PF05701.6 AEO62036.1 - 1.7 7.0 36.7 0.034 12.6 20.7 1.5 2 0 0 2 2 2 0 Weak chloroplast movement under blue light Mnd1 PF03962.10 AEO62036.1 - 2.2 7.9 33.7 0.48 10.0 8.1 2.5 1 1 1 2 2 2 0 Mnd1 family APG6 PF04111.7 AEO62036.1 - 2.6 7.0 36.9 1.3 8.0 15.8 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 TMF_DNA_bd PF12329.3 AEO62036.1 - 2.7 7.8 41.0 0.35 10.6 4.5 3.5 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding TMF_TATA_bd PF12325.3 AEO62036.1 - 2.8 7.7 32.2 2.2 7.9 3.8 3.7 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding FUSC PF04632.7 AEO62036.1 - 3.6 5.9 8.7 13 4.0 6.1 2.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family FlxA PF14282.1 AEO62036.1 - 4.3 7.3 43.3 37 4.3 12.8 4.0 1 1 1 2 2 1 0 FlxA-like protein Myosin_tail_1 PF01576.14 AEO62036.1 - 4.4 4.8 35.9 2.6 5.6 18.9 1.6 1 1 1 2 2 2 0 Myosin tail DUF3450 PF11932.3 AEO62036.1 - 4.7 6.4 34.6 5.8 6.1 13.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF4239 PF14023.1 AEO62036.1 - 6.7 6.0 8.9 8.6 5.6 5.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4239) DUF812 PF05667.6 AEO62036.1 - 6.8 5.0 31.2 17 3.7 20.9 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Filament PF00038.16 AEO62036.1 - 7.6 5.8 34.5 2.3 7.6 10.3 2.1 1 1 1 2 2 2 0 Intermediate filament protein Lebercilin PF15619.1 AEO62036.1 - 7.9 5.8 34.6 15 4.9 24.0 1.4 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Fib_alpha PF08702.5 AEO62036.1 - 8.2 6.5 25.9 0.73 9.9 8.0 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Tubulin PF00091.20 AEO62037.1 - 1.1e-69 234.5 0.0 1.5e-69 234.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 AEO62037.1 - 4.8e-49 165.5 0.1 8.2e-49 164.8 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 AEO62037.1 - 0.0011 18.4 0.0 0.0027 17.1 0.0 1.6 2 0 0 2 2 2 1 Tubulin domain Lipase_3 PF01764.20 AEO62037.1 - 0.088 12.4 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) BTB_2 PF02214.17 AEO62038.1 - 4.1e-07 30.0 0.1 0.0027 17.8 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain DUF342 PF03961.8 AEO62039.1 - 0.048 12.0 10.5 0.069 11.5 7.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) IFT57 PF10498.4 AEO62039.1 - 0.15 10.8 12.2 0.22 10.2 8.5 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 ADIP PF11559.3 AEO62039.1 - 0.15 11.9 20.5 0.021 14.7 11.2 1.7 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Seryl_tRNA_N PF02403.17 AEO62039.1 - 0.35 10.9 26.8 0.03 14.3 7.6 2.8 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CotH PF08757.6 AEO62039.1 - 0.74 9.0 4.4 0.87 8.7 0.0 2.2 2 0 0 2 2 2 0 CotH protein Fib_alpha PF08702.5 AEO62039.1 - 0.96 9.5 9.3 5.4 7.1 5.9 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family GAS PF13851.1 AEO62039.1 - 1.8 7.6 27.5 0.41 9.8 15.6 2.4 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Fungal_trans_2 PF11951.3 AEO62039.1 - 4 5.9 6.7 7.8 4.9 3.2 2.4 2 1 0 2 2 2 0 Fungal specific transcription factor domain V_ATPase_I PF01496.14 AEO62039.1 - 5.1 4.8 16.9 26 2.4 11.7 2.0 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family MAD PF05557.8 AEO62040.1 - 0.00079 17.6 30.1 0.0012 17.0 20.9 1.2 1 0 0 1 1 1 1 Mitotic checkpoint protein DUF4191 PF13829.1 AEO62040.1 - 0.021 13.9 2.5 0.044 12.9 1.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Lebercilin PF15619.1 AEO62040.1 - 4.2 6.7 39.9 0.31 10.4 23.2 2.3 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF4613 PF15390.1 AEO62040.1 - 5.3 5.1 13.8 10 4.1 9.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) AAA_13 PF13166.1 AEO62040.1 - 8.6 4.6 22.3 13 4.0 15.5 1.2 1 0 0 1 1 1 0 AAA domain Cyt-b5 PF00173.23 AEO62041.1 - 1.3e-09 37.6 0.0 2.3e-09 36.8 0.0 1.5 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TFIIE-A_C-term PF11521.3 AEO62041.1 - 0.95 9.4 5.6 1.9 8.5 3.9 1.5 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha CENP-X PF09415.5 AEO62042.1 - 1.1e-26 92.3 0.1 1.6e-26 91.9 0.1 1.2 1 0 0 1 1 1 1 CENP-S associating Centromere protein X Mito_carr PF00153.22 AEO62043.1 - 6.8e-67 221.2 4.4 3.1e-23 81.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_S25 PF03297.10 AEO62044.1 - 3.3e-40 136.3 6.6 3.6e-40 136.2 4.6 1.0 1 0 0 1 1 1 1 S25 ribosomal protein RNA_pol_Rpc34 PF05158.7 AEO62044.1 - 0.00089 18.5 0.3 0.0013 18.0 0.1 1.3 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit Rrf2 PF02082.15 AEO62044.1 - 0.012 15.7 0.1 0.017 15.2 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator HTH_24 PF13412.1 AEO62044.1 - 0.013 14.8 0.1 0.02 14.2 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR_2 PF12802.2 AEO62044.1 - 0.018 14.7 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 MarR family TrmB PF01978.14 AEO62044.1 - 0.02 14.5 0.2 0.029 14.0 0.2 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_DeoR PF08220.7 AEO62044.1 - 0.022 14.3 0.1 0.03 13.8 0.1 1.2 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain FeoC PF09012.5 AEO62044.1 - 0.1 12.3 0.4 0.28 10.9 0.0 1.8 2 0 0 2 2 2 0 FeoC like transcriptional regulator HTH_11 PF08279.7 AEO62044.1 - 0.12 12.0 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 HTH domain Ribosomal_S7 PF00177.16 AEO62045.1 - 1.6e-41 141.3 0.9 1.9e-41 141.0 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Acetyltransf_1 PF00583.19 AEO62046.1 - 1.6e-09 37.6 0.1 1.1e-06 28.5 0.0 3.1 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AEO62046.1 - 2e-06 27.8 0.0 1.3e-05 25.2 0.0 2.2 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.1 AEO62046.1 - 3.5e-05 24.3 0.0 0.14 12.7 0.0 2.7 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 AEO62046.1 - 0.00033 20.4 0.0 0.0007 19.4 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 AEO62046.1 - 0.025 14.3 0.0 0.18 11.6 0.0 2.2 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_3 PF13302.1 AEO62046.1 - 0.033 14.3 0.0 0.17 12.0 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Optomotor-blind PF11078.3 AEO62046.1 - 0.043 14.1 0.2 0.092 13.1 0.1 1.6 1 0 0 1 1 1 0 Optomotor-blind protein N-terminal region Acetyltransf_10 PF13673.1 AEO62046.1 - 0.082 13.0 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PIGA PF08288.7 AEO62048.1 - 1.2e-46 156.9 4.5 2.4e-46 156.0 1.3 2.5 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 AEO62048.1 - 9e-29 100.0 0.0 1.4e-28 99.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 AEO62048.1 - 8e-17 61.5 1.5 1.6e-16 60.5 1.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 AEO62048.1 - 8.5e-16 58.3 0.0 1.5e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 AEO62048.1 - 1.9e-15 57.3 0.0 3.8e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.1 AEO62048.1 - 2e-06 27.7 0.5 3.3e-06 26.9 0.3 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 AEO62048.1 - 0.00046 20.3 0.0 0.0013 19.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 AEO62048.1 - 0.1 12.0 0.1 0.31 10.4 0.0 1.7 1 1 1 2 2 2 0 Starch synthase catalytic domain DEAD PF00270.24 AEO62049.1 - 7.8e-32 110.0 0.1 6.9e-15 54.9 0.0 2.4 1 1 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 AEO62049.1 - 2.2e-21 75.5 0.1 5.5e-21 74.2 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CDC45 PF02724.9 AEO62049.1 - 2.9e-06 25.6 3.5 2.9e-06 25.6 2.4 3.1 2 1 1 3 3 3 1 CDC45-like protein ResIII PF04851.10 AEO62049.1 - 1.5e-05 24.9 0.0 1.5e-05 24.9 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 AEO62049.1 - 0.094 12.4 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain HSP70 PF00012.15 AEO62050.1 - 3.1e-64 216.9 5.6 7.7e-59 199.1 0.0 3.2 3 0 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.8 AEO62050.1 - 0.00072 18.2 0.1 0.0053 15.4 0.0 2.4 2 0 0 2 2 2 1 MreB/Mbl protein Syntaxin-6_N PF09177.6 AEO62050.1 - 0.018 15.3 3.6 0.032 14.6 0.6 3.0 2 2 0 2 2 2 0 Syntaxin 6, N-terminal Herpes_capsid PF06112.6 AEO62050.1 - 3.1 7.8 13.4 5.2 7.0 3.3 3.1 3 0 0 3 3 3 0 Gammaherpesvirus capsid protein SlyX PF04102.7 AEO62051.1 - 0.0011 19.2 0.9 0.0011 19.2 0.6 2.2 2 0 0 2 2 2 1 SlyX Tektin PF03148.9 AEO62051.1 - 0.0012 17.4 0.9 0.002 16.7 0.7 1.3 1 0 0 1 1 1 1 Tektin family Allexi_40kDa PF05549.6 AEO62051.1 - 0.0017 17.7 1.8 0.0022 17.3 1.2 1.1 1 0 0 1 1 1 1 Allexivirus 40kDa protein PspA_IM30 PF04012.7 AEO62051.1 - 0.0017 17.7 1.0 0.0017 17.7 0.7 1.7 2 0 0 2 2 2 1 PspA/IM30 family HCR PF07111.7 AEO62051.1 - 0.0054 14.8 4.7 0.0082 14.2 3.3 1.2 1 0 0 1 1 1 1 Alpha helical coiled-coil rod protein (HCR) DUF241 PF03087.9 AEO62051.1 - 0.0089 15.5 0.9 0.015 14.7 0.6 1.3 1 0 0 1 1 1 1 Arabidopsis protein of unknown function Herpes_UL6 PF01763.11 AEO62051.1 - 0.011 13.9 2.6 0.013 13.6 1.8 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like SPX PF03105.14 AEO62051.1 - 0.016 15.0 0.2 0.019 14.7 0.2 1.2 1 0 0 1 1 1 0 SPX domain AAA_13 PF13166.1 AEO62051.1 - 0.023 13.1 0.3 0.034 12.6 0.2 1.2 1 0 0 1 1 1 0 AAA domain DUF1395 PF07160.7 AEO62051.1 - 0.027 13.9 2.9 0.036 13.5 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1395) DUF16 PF01519.11 AEO62051.1 - 0.033 14.3 0.9 0.033 14.3 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF16 TMF_DNA_bd PF12329.3 AEO62051.1 - 0.036 13.8 1.1 0.036 13.8 0.8 1.6 2 0 0 2 2 1 0 TATA element modulatory factor 1 DNA binding NPV_P10 PF05531.7 AEO62051.1 - 0.039 14.2 0.1 0.067 13.4 0.1 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.4 AEO62051.1 - 0.05 13.7 2.3 0.91 9.6 0.2 2.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Striatin PF08232.7 AEO62051.1 - 0.056 13.7 4.5 0.091 13.0 3.1 1.3 1 0 0 1 1 1 0 Striatin family Viral_P18 PF04521.8 AEO62051.1 - 0.062 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein Fib_alpha PF08702.5 AEO62051.1 - 0.083 13.0 0.2 0.083 13.0 0.2 1.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family ATG16 PF08614.6 AEO62051.1 - 0.11 12.3 6.2 0.066 13.0 0.9 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Hemerythrin PF01814.18 AEO62051.1 - 0.12 12.5 0.2 0.16 12.0 0.1 1.2 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain Filament PF00038.16 AEO62051.1 - 0.15 11.5 6.9 0.14 11.6 4.2 1.3 1 1 0 1 1 1 0 Intermediate filament protein IFT57 PF10498.4 AEO62051.1 - 0.17 10.6 3.8 0.072 11.8 1.2 1.4 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 Rab5-bind PF09311.6 AEO62051.1 - 0.22 11.4 9.6 0.31 10.9 6.6 1.1 1 0 0 1 1 1 0 Rabaptin-like protein DUF972 PF06156.8 AEO62051.1 - 0.24 11.7 1.9 0.41 11.0 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Fmp27_WPPW PF10359.4 AEO62051.1 - 0.3 9.4 3.9 0.4 9.0 2.7 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain APG6 PF04111.7 AEO62051.1 - 0.56 9.1 5.1 0.77 8.7 3.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 SGT1 PF07093.6 AEO62051.1 - 1 7.6 6.6 1.2 7.4 4.6 1.1 1 0 0 1 1 1 0 SGT1 protein zf-C4H2 PF10146.4 AEO62051.1 - 2.1 8.3 9.2 4.1 7.3 6.4 1.6 1 1 0 1 1 1 0 Zinc finger-containing protein DUF4407 PF14362.1 AEO62051.1 - 2.4 7.0 6.1 3.4 6.5 4.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF605 PF04652.11 AEO62051.1 - 5.2 6.3 18.1 6.3 6.0 12.5 1.1 1 0 0 1 1 1 0 Vta1 like XhlA PF10779.4 AEO62051.1 - 8.1 6.4 8.3 0.12 12.3 0.8 1.6 2 0 0 2 2 1 0 Haemolysin XhlA APH PF01636.18 AEO62052.1 - 1.1e-10 41.6 1.5 5.7e-10 39.3 0.0 2.2 1 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 AEO62052.1 - 0.0037 16.8 0.0 0.007 15.9 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 AEO62052.1 - 0.2 10.7 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase DUF1759 PF03564.10 AEO62052.1 - 0.4 10.4 1.3 0.58 9.9 0.1 1.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1759) Abhydrolase_2 PF02230.11 AEO62053.1 - 2.5e-31 108.8 0.0 1.3e-22 80.2 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 AEO62053.1 - 4.7e-11 43.0 6.1 6.9e-11 42.4 4.2 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 AEO62053.1 - 2.4e-09 37.0 1.3 5.7e-09 35.8 0.9 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 AEO62053.1 - 1.4e-05 24.4 0.3 0.11 11.7 0.0 3.4 3 1 1 4 4 4 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 AEO62053.1 - 6.8e-05 22.5 0.3 0.00028 20.5 0.2 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.8 AEO62053.1 - 0.0003 20.2 0.0 0.0022 17.4 0.0 2.2 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Glyco_hydro_11 PF00457.12 AEO62054.1 - 3.1e-72 241.7 16.7 3.6e-72 241.5 11.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Ceramidase PF05875.7 AEO62056.1 - 2.8e-31 108.6 0.2 3.2e-31 108.4 0.2 1.0 1 0 0 1 1 1 1 Ceramidase Grp1_Fun34_YaaH PF01184.14 AEO62056.1 - 0.094 11.9 4.8 0.17 11.1 3.3 1.4 1 0 0 1 1 1 0 GPR1/FUN34/yaaH family Bromodomain PF00439.20 AEO62057.1 - 2e-13 50.0 0.0 5e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 Bromodomain Ax_dynein_light PF10211.4 AEO62057.1 - 0.3 10.9 0.3 0.51 10.1 0.2 1.3 1 0 0 1 1 1 0 Axonemal dynein light chain HSP70 PF00012.15 AEO62058.1 - 3.7e-09 35.0 0.0 1.4e-06 26.5 0.0 2.6 2 1 0 2 2 2 2 Hsp70 protein Gaa1 PF04114.9 AEO62060.1 - 0.0047 15.6 1.4 0.0075 15.0 1.0 1.2 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component DUF805 PF05656.9 AEO62060.1 - 0.022 14.5 7.8 1.6 8.5 0.0 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF805) PMT_2 PF13231.1 AEO62061.1 - 0.28 11.0 8.1 0.75 9.6 0.9 2.5 1 1 1 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase Pkinase PF00069.20 AEO62063.1 - 2.7e-24 85.7 0.0 4e-23 81.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 AEO62063.1 - 4.1e-11 42.4 0.0 1.4e-10 40.6 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 AEO62063.1 - 0.0049 15.9 0.0 0.0076 15.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 AEO62063.1 - 0.028 14.1 0.5 0.12 12.1 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 AEO62063.1 - 0.09 11.5 0.1 0.14 10.9 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Tropomyosin PF00261.15 AEO62064.1 - 0.0038 16.3 11.6 0.0084 15.2 8.0 1.5 1 1 0 1 1 1 1 Tropomyosin ScpA_ScpB PF02616.9 AEO62064.1 - 0.0054 16.3 1.2 0.0096 15.5 0.8 1.3 1 0 0 1 1 1 1 ScpA/B protein Mnd1 PF03962.10 AEO62064.1 - 0.025 14.2 3.7 0.047 13.3 2.6 1.4 1 0 0 1 1 1 0 Mnd1 family AAA_13 PF13166.1 AEO62064.1 - 0.048 12.1 1.4 0.069 11.6 1.0 1.2 1 0 0 1 1 1 0 AAA domain DUF3987 PF13148.1 AEO62064.1 - 0.052 12.1 5.2 0.39 9.2 2.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) DUF883 PF05957.8 AEO62064.1 - 0.14 12.5 3.3 0.28 11.5 1.9 1.8 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) IncA PF04156.9 AEO62064.1 - 0.21 11.1 4.1 0.5 9.9 2.9 1.6 1 0 0 1 1 1 0 IncA protein VIT1 PF01988.14 AEO62064.1 - 0.21 11.0 2.9 0.32 10.4 2.0 1.2 1 0 0 1 1 1 0 VIT family FUSC PF04632.7 AEO62064.1 - 0.88 7.9 3.2 0.99 7.7 0.7 1.9 2 0 0 2 2 2 0 Fusaric acid resistance protein family HNH_2 PF13391.1 AEO62065.1 - 4.8e-13 48.6 0.0 1e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease IBR PF01485.16 AEO62066.1 - 1.8e-17 62.9 25.3 9.3e-13 47.8 1.6 3.7 3 1 1 4 4 4 2 IBR domain Baculo_E56 PF04639.7 AEO62066.1 - 0.056 12.1 0.2 0.095 11.3 0.2 1.3 1 0 0 1 1 1 0 Baculoviral E56 protein, specific to ODV envelope BAF1_ABF1 PF04684.8 AEO62066.1 - 4.3 6.0 8.5 8.9 5.0 5.9 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor zf-RING_2 PF13639.1 AEO62066.1 - 6 6.7 30.9 0.33 10.8 3.8 3.3 3 0 0 3 3 3 0 Ring finger domain His_Phos_1 PF00300.17 AEO62067.1 - 2e-23 83.2 0.0 2e-22 79.9 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 AEO62067.1 - 0.049 12.9 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) DNA_binding_1 PF01035.15 AEO62068.1 - 7.8e-23 80.0 0.1 9.9e-23 79.6 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain RasGEF PF00617.14 AEO62069.1 - 1.7e-55 187.7 0.1 3e-55 186.8 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 AEO62069.1 - 3.2e-18 65.7 0.0 7.8e-18 64.4 0.0 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.1 AEO62069.1 - 2.7e-06 26.8 0.0 7.2e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 AEO62069.1 - 4.8e-05 22.6 0.0 0.0001 21.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 AEO62069.1 - 0.0063 15.9 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Jacalin PF01419.12 AEO62071.1 - 0.033 14.0 0.0 0.076 12.8 0.0 1.6 2 0 0 2 2 2 0 Jacalin-like lectin domain Ribosomal_L11_N PF03946.9 AEO62071.1 - 0.034 13.6 0.0 0.069 12.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11, N-terminal domain MFS_1 PF07690.11 AEO62072.1 - 1.7e-16 59.8 29.9 2.9e-16 59.1 20.7 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 AEO62072.1 - 1.7e-12 47.0 6.9 1.7e-12 47.0 4.8 2.6 4 0 0 4 4 4 1 Ion channel regulatory protein UNC-93 AcetylCoA_hydro PF02550.10 AEO62073.1 - 0.0015 18.3 0.0 0.0016 18.2 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hydro PF02550.10 AEO62074.1 - 5.4e-40 137.2 0.0 8.4e-40 136.6 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 AEO62074.1 - 1.9e-38 131.5 0.0 2.7e-38 131.0 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain CBM_1 PF00734.13 AEO62076.1 - 4e-14 51.9 8.7 1.2e-13 50.4 6.0 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain Polysacc_lyase PF14099.1 AEO62076.1 - 0.17 11.4 5.0 0.59 9.7 3.5 1.8 1 1 0 1 1 1 0 Polysaccharide lyase MFS_1 PF07690.11 AEO62077.1 - 2e-26 92.5 51.5 1.4e-23 83.1 22.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO62077.1 - 6.3e-15 54.6 29.2 1.1e-14 53.9 20.2 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter DUF2583 PF10762.4 AEO62077.1 - 1.7 8.8 5.0 0.42 10.7 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) HET PF06985.6 AEO62078.1 - 0.012 15.7 0.0 0.017 15.2 0.0 1.5 1 1 0 1 1 1 0 Heterokaryon incompatibility protein (HET) Hairpins PF04877.7 AEO62080.1 - 0.012 15.0 2.2 0.012 15.0 1.5 1.1 1 0 0 1 1 1 0 HrpZ Epimerase PF01370.16 AEO62081.1 - 4e-16 59.1 0.0 9e-09 35.1 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 AEO62081.1 - 1.1e-09 37.5 0.0 2.1e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.20 AEO62081.1 - 2.4e-08 34.0 0.0 4.3e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 AEO62081.1 - 7e-08 31.7 0.0 1.3e-05 24.3 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain 3Beta_HSD PF01073.14 AEO62081.1 - 0.0024 16.6 0.0 0.083 11.5 0.0 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 AEO62081.1 - 0.0061 16.2 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 AEO62081.1 - 0.075 11.9 0.0 1.5 7.6 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DUF3439 PF11921.3 AEO62081.1 - 0.87 9.3 9.3 0.22 11.2 4.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Sporozoite_P67 PF05642.6 AEO62081.1 - 1.9 6.2 7.2 2.7 5.7 5.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen APH PF01636.18 AEO62082.1 - 4.8e-20 72.3 0.1 1e-19 71.2 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 AEO62082.1 - 1.8e-05 24.4 0.0 2.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 AEO62082.1 - 3.4e-05 23.2 0.0 0.065 12.5 0.0 2.3 2 0 0 2 2 2 2 RIO1 family DUF1679 PF07914.6 AEO62082.1 - 0.0095 14.6 0.0 0.016 13.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.15 AEO62082.1 - 0.055 12.6 0.0 0.088 11.9 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Lipase_GDSL_2 PF13472.1 AEO62082.1 - 0.061 13.4 0.0 1.1 9.4 0.0 2.1 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family SR-25 PF10500.4 AEO62083.1 - 1.1 8.6 22.3 2.3 7.6 15.4 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.4 AEO62083.1 - 3.2 5.9 16.9 4.5 5.4 11.7 1.1 1 0 0 1 1 1 0 Transmembrane protein TPR_12 PF13424.1 AEO62085.1 - 0.13 12.2 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_4 PF07721.9 AEO62085.1 - 0.31 11.6 5.3 0.32 11.5 0.2 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat Mucin PF01456.12 AEO62086.1 - 0.00082 19.1 19.0 0.0019 17.9 13.2 1.6 1 1 0 1 1 1 1 Mucin-like glycoprotein Dicty_REP PF05086.7 AEO62086.1 - 0.22 9.2 3.5 0.29 8.8 2.4 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.3 AEO62086.1 - 0.99 9.1 16.7 2.2 8.0 11.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.6 AEO62086.1 - 5 4.9 16.0 7.3 4.4 11.1 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 HET PF06985.6 AEO62087.1 - 4.9e-26 91.5 0.0 9.2e-26 90.6 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1992 PF09350.5 AEO62088.1 - 5.7e-25 86.9 0.4 1.3e-24 85.7 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) DUF896 PF05979.7 AEO62088.1 - 0.2 11.2 0.6 0.57 9.8 0.0 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) Acetyltransf_1 PF00583.19 AEO62089.1 - 6.6e-06 26.0 0.5 1.1e-05 25.3 0.3 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 AEO62089.1 - 4.5e-05 23.5 0.0 6.1e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 AEO62089.1 - 7.1e-05 22.9 0.7 0.00012 22.1 0.5 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 AEO62089.1 - 0.0038 17.0 0.3 0.0056 16.5 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 AEO62089.1 - 0.005 16.5 0.1 0.013 15.2 0.1 1.6 1 1 0 1 1 1 1 FR47-like protein TauD PF02668.11 AEO62090.1 - 3.2e-26 92.5 0.0 6.1e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 AEO62090.1 - 0.0022 16.9 0.0 0.0042 16.0 0.0 1.3 1 0 0 1 1 1 1 CsiD Zn_clus PF00172.13 AEO62090.1 - 0.16 11.8 5.8 0.31 10.9 4.0 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 AEO62091.1 - 2e-05 23.8 0.0 4.2e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain DUF4603 PF15376.1 AEO62091.1 - 2.5 5.1 4.9 3.6 4.6 3.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) MgsA_C PF12002.3 AEO62092.1 - 9.8e-61 204.3 0.2 2.8e-60 202.8 0.0 1.8 2 0 0 2 2 2 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 AEO62092.1 - 4.4e-13 49.5 0.0 8.1e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 AEO62092.1 - 1.6e-10 40.4 0.0 6.5e-10 38.4 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 AEO62092.1 - 9.5e-06 25.7 0.8 0.0033 17.4 0.0 3.2 2 2 1 3 3 3 1 AAA ATPase domain Sigma54_activat PF00158.21 AEO62092.1 - 1.4e-05 24.6 0.0 0.00055 19.4 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.1 AEO62092.1 - 8.3e-05 22.7 0.4 0.0005 20.2 0.3 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AEO62092.1 - 8.7e-05 22.2 0.6 0.00032 20.4 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_14 PF13173.1 AEO62092.1 - 0.00029 20.7 0.0 0.00051 19.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 AEO62092.1 - 0.00037 20.2 0.1 0.0057 16.3 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 AEO62092.1 - 0.00045 19.4 0.0 0.21 10.7 0.0 2.2 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 AEO62092.1 - 0.00072 18.5 0.0 0.0011 17.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.8 AEO62092.1 - 0.0015 17.3 0.0 0.0059 15.3 0.0 1.7 2 0 0 2 2 2 1 TIP49 C-terminus AAA_17 PF13207.1 AEO62092.1 - 0.0038 18.0 0.0 0.0076 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 AEO62092.1 - 0.014 15.2 0.1 2.7 7.8 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_3 PF07726.6 AEO62092.1 - 0.019 14.5 0.0 0.045 13.3 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 AEO62092.1 - 0.038 13.6 0.0 1.6 8.3 0.0 2.3 1 1 1 2 2 2 0 DNA polymerase III, delta subunit SKI PF01202.17 AEO62092.1 - 0.055 13.3 0.0 0.094 12.5 0.0 1.3 1 0 0 1 1 1 0 Shikimate kinase AAA_28 PF13521.1 AEO62092.1 - 0.063 13.2 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 AEO62092.1 - 0.09 13.0 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain CPT PF07931.7 AEO62092.1 - 0.16 11.6 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein NB-ARC PF00931.17 AEO62092.1 - 0.18 10.6 0.0 0.29 9.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_10 PF12846.2 AEO62092.1 - 0.41 10.0 2.3 8.2 5.7 0.1 3.0 2 2 1 4 4 4 0 AAA-like domain Fe-S_biosyn PF01521.15 AEO62093.1 - 4.1e-20 71.7 0.0 5.4e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Hamartin PF04388.7 AEO62093.1 - 0.2 10.3 3.0 0.25 9.9 2.1 1.1 1 0 0 1 1 1 0 Hamartin protein DUF1741 PF08427.5 AEO62094.1 - 1.4e-85 286.5 0.0 1.1e-84 283.6 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1741) DUF336 PF03928.9 AEO62096.1 - 9.1e-15 54.6 4.3 2e-12 47.0 3.0 2.7 1 1 0 1 1 1 1 Domain of unknown function (DUF336) CLN3 PF02487.12 AEO62098.1 - 5.5e-102 341.5 24.3 2.4e-56 191.2 0.4 3.0 2 1 1 3 3 3 3 CLN3 protein zf-RING_2 PF13639.1 AEO62099.1 - 4.7e-14 51.9 10.6 4.7e-14 51.9 7.3 1.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 AEO62099.1 - 8.8e-09 35.2 12.2 8.8e-09 35.2 8.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 AEO62099.1 - 2.6e-07 30.2 9.0 5.4e-07 29.2 6.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 AEO62099.1 - 6.9e-07 28.8 10.2 1.2e-06 27.9 7.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 AEO62099.1 - 7.2e-07 29.2 11.0 1.7e-06 28.0 7.6 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 AEO62099.1 - 6.4e-06 25.7 10.0 6.4e-06 25.7 6.9 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 AEO62099.1 - 0.0012 18.3 7.9 0.003 17.0 5.5 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 AEO62099.1 - 0.0094 15.7 5.5 0.016 15.0 3.8 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 AEO62099.1 - 0.013 15.5 7.9 0.026 14.5 5.5 1.5 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.24 AEO62099.1 - 0.18 11.4 6.6 0.43 10.2 4.5 1.7 1 1 0 1 1 1 0 PHD-finger zf-RING_UBOX PF13445.1 AEO62099.1 - 0.26 11.0 8.7 0.42 10.3 3.1 2.5 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_4 PF14570.1 AEO62099.1 - 0.27 10.8 5.4 0.59 9.7 3.7 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-HC5HC2H_2 PF13832.1 AEO62099.1 - 0.34 10.9 5.0 0.67 9.9 3.5 1.5 1 1 0 1 1 1 0 PHD-zinc-finger like domain Baculo_IE-1 PF05290.6 AEO62099.1 - 0.37 10.5 5.0 0.55 9.9 3.4 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4_4 PF15227.1 AEO62099.1 - 3 7.7 11.7 5.1 7.0 6.8 2.3 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Prok-RING_1 PF14446.1 AEO62099.1 - 3.7 7.3 7.1 14 5.4 4.9 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 C1_1 PF00130.17 AEO62099.1 - 5 6.9 9.2 0.7 9.6 3.3 1.7 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF4454 PF14628.1 AEO62100.1 - 0.089 12.4 0.3 0.12 12.0 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4454) GCOM2 PF15328.1 AEO62103.1 - 0.016 14.9 2.2 0.016 14.9 1.5 1.8 2 1 0 2 2 2 0 Putative GRINL1B complex locus protein 2 CENP-F_leu_zip PF10473.4 AEO62103.1 - 0.032 14.0 1.4 0.032 14.0 1.0 1.9 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TBPIP PF07106.8 AEO62103.1 - 0.073 12.6 5.2 0.4 10.2 1.5 2.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) 5_3_exonuc PF01367.15 AEO62103.1 - 0.13 12.5 0.6 0.27 11.4 0.4 1.5 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold DivIC PF04977.10 AEO62103.1 - 0.25 10.8 5.6 0.88 9.0 3.7 1.9 2 0 0 2 2 2 0 Septum formation initiator DUF972 PF06156.8 AEO62103.1 - 0.55 10.6 2.6 1.3 9.4 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) MerR_2 PF13591.1 AEO62103.1 - 0.61 9.7 5.2 0.091 12.3 0.6 1.8 2 0 0 2 2 2 0 MerR HTH family regulatory protein DUF3373 PF11853.3 AEO62103.1 - 1.3 7.4 6.8 1.6 7.1 4.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3373) HeLo PF14479.1 AEO62104.1 - 3.1e-41 141.4 0.0 3.7e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 Prion-inhibition and propagation Dynamin_N PF00350.18 AEO62105.1 - 2.4e-29 102.2 0.2 5.3e-29 101.1 0.1 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 AEO62105.1 - 3.4e-17 62.1 0.0 6.9e-17 61.1 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.18 AEO62105.1 - 1.2e-05 25.2 0.1 0.0001 22.2 0.0 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.13 AEO62105.1 - 0.00035 20.4 1.6 0.00092 19.0 0.3 2.3 2 0 0 2 2 2 1 Dynamin GTPase effector domain Miro PF08477.8 AEO62105.1 - 0.018 15.5 0.0 0.082 13.4 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein AAA_21 PF13304.1 AEO62105.1 - 0.021 14.8 0.0 0.067 13.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 AEO62105.1 - 0.034 13.6 0.0 0.11 12.0 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.13 AEO62105.1 - 0.07 12.4 0.0 6.7 5.9 0.1 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_23 PF13476.1 AEO62105.1 - 0.55 10.5 3.8 0.25 11.6 0.3 2.3 2 1 0 2 2 2 0 AAA domain Metallophos PF00149.23 AEO62106.1 - 0.00074 18.9 0.2 0.0068 15.8 0.2 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1814 PF08843.6 AEO62108.1 - 0.0015 18.3 0.0 0.0017 18.1 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF1814) Peptidase_M28 PF04389.12 AEO62109.1 - 2.4e-35 121.8 0.0 4.2e-35 121.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 AEO62109.1 - 4e-17 61.7 0.6 7.3e-17 60.9 0.4 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 AEO62109.1 - 1.4e-07 31.1 0.0 3.3e-07 30.0 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 Nicastrin PF05450.10 AEO62109.1 - 0.13 11.4 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Nicastrin Pyrophosphatase PF00719.14 AEO62110.1 - 2e-47 160.5 0.0 2.6e-47 160.1 0.0 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase APH PF01636.18 AEO62111.1 - 9.9e-13 48.3 0.0 2.5e-12 47.0 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 AEO62111.1 - 7.1e-05 21.6 0.0 0.0001 21.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.15 AEO62111.1 - 0.00014 21.1 0.0 0.00024 20.3 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 AEO62111.1 - 0.0015 18.1 0.0 0.0026 17.3 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pectate_lyase_3 PF12708.2 AEO62113.1 - 1.8e-08 34.7 0.0 2.2e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Pectate lyase superfamily protein Acetyltransf_1 PF00583.19 AEO62114.1 - 0.021 14.8 0.2 0.036 14.1 0.1 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family TRAP_alpha PF03896.11 AEO62115.1 - 0.0023 16.9 0.1 0.0029 16.6 0.1 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit BSP_II PF05432.6 AEO62115.1 - 0.0056 15.9 2.3 0.0071 15.6 1.6 1.1 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) DUF702 PF05142.7 AEO62115.1 - 0.011 15.9 0.3 0.014 15.5 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF702) Atrophin-1 PF03154.10 AEO62115.1 - 0.02 13.0 3.5 0.022 12.9 2.4 1.1 1 0 0 1 1 1 0 Atrophin-1 family DUF2457 PF10446.4 AEO62115.1 - 0.024 13.4 9.2 0.031 13.0 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Myc_N PF01056.13 AEO62115.1 - 0.079 12.1 1.0 0.089 11.9 0.7 1.1 1 0 0 1 1 1 0 Myc amino-terminal region EcoRI_methylase PF13651.1 AEO62115.1 - 0.14 11.1 0.3 0.18 10.8 0.2 1.1 1 0 0 1 1 1 0 Adenine-specific methyltransferase EcoRI CDC45 PF02724.9 AEO62115.1 - 0.31 9.0 6.1 0.39 8.6 4.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2058 PF09831.4 AEO62115.1 - 0.69 9.7 6.6 1 9.2 4.6 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) DUF1777 PF08648.7 AEO62115.1 - 0.94 9.1 13.9 1.5 8.5 9.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) VID27 PF08553.5 AEO62115.1 - 2.4 6.2 6.1 3.1 5.9 4.2 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein Utp12 PF04003.7 AEO62116.1 - 1.2e-22 79.8 0.0 1.8e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Bromodomain PF00439.20 AEO62117.1 - 1.5e-40 136.9 1.1 5.1e-24 84.0 0.2 3.0 3 0 0 3 3 3 2 Bromodomain RBM1CTR PF08081.6 AEO62118.1 - 0.44 10.3 4.0 0.83 9.4 0.4 2.3 2 0 0 2 2 2 0 RBM1CTR (NUC064) family DUF4199 PF13858.1 AEO62119.1 - 0.0028 17.6 0.1 0.0036 17.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4199) DUF4117 PF13491.1 AEO62119.1 - 0.005 16.3 0.6 0.0079 15.6 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4117) DUF981 PF06168.6 AEO62119.1 - 0.017 14.9 0.4 0.021 14.5 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF981) YajC PF02699.10 AEO62119.1 - 0.065 12.9 0.0 0.092 12.4 0.0 1.2 1 0 0 1 1 1 0 Preprotein translocase subunit ATP_synt_I PF03899.10 AEO62119.1 - 0.39 10.9 3.4 0.62 10.2 1.1 2.0 2 1 0 2 2 2 0 ATP synthase I chain Sugar_tr PF00083.19 AEO62120.1 - 2.1e-115 385.8 17.6 2.4e-115 385.7 12.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 AEO62120.1 - 1.2e-19 70.2 37.3 2.2e-14 52.9 6.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Rxt3 PF08642.5 AEO62121.1 - 7.4e-30 103.5 0.0 3.2e-29 101.4 0.0 2.2 1 0 0 1 1 1 1 Histone deacetylation protein Rxt3 LCCL PF03815.14 AEO62121.1 - 1e-05 25.4 0.0 0.00041 20.2 0.0 2.5 2 0 0 2 2 2 1 LCCL domain DUF1674 PF07896.7 AEO62122.1 - 3.4e-15 55.9 2.5 7.5e-15 54.8 1.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) AKAP2_C PF15304.1 AEO62122.1 - 0.037 13.6 9.7 0.045 13.3 6.7 1.1 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus TFIIA PF03153.8 AEO62122.1 - 1 9.1 8.4 1.5 8.6 5.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mucin PF01456.12 AEO62122.1 - 1.4 8.6 35.3 0.58 9.9 13.4 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein CDK2AP PF09806.4 AEO62122.1 - 2.1 8.5 13.6 2.6 8.2 3.4 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Laminin_G_3 PF13385.1 AEO62123.1 - 1.4e-09 38.3 3.2 7.5e-05 23.0 0.0 3.3 3 0 0 3 3 3 2 Concanavalin A-like lectin/glucanases superfamily Melibiase PF02065.13 AEO62124.1 - 2.8e-20 72.3 1.4 1.2e-17 63.7 0.0 2.5 2 1 1 3 3 3 2 Melibiase Pkinase PF00069.20 AEO62127.1 - 1.4e-24 86.6 0.0 6.2e-23 81.2 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 AEO62127.1 - 1.1e-09 37.7 0.0 1.7e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 AEO62127.1 - 0.092 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL MFS_1 PF07690.11 AEO62128.1 - 1.6e-34 119.1 12.1 6.6e-18 64.5 1.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 AEO62128.1 - 8.5e-07 27.8 6.1 8.5e-07 27.8 4.2 2.6 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.2 AEO62128.1 - 0.00021 21.0 3.4 0.00031 20.4 0.2 2.7 3 0 0 3 3 3 1 MFS_1 like family MFS_2 PF13347.1 AEO62128.1 - 0.00033 19.1 4.3 0.00033 19.1 3.0 3.1 2 2 1 3 3 3 1 MFS/sugar transport protein TRI12 PF06609.8 AEO62128.1 - 0.16 10.1 7.6 0.039 12.1 1.7 2.0 1 1 1 2 2 2 0 Fungal trichothecene efflux pump (TRI12) DUF2061 PF09834.4 AEO62128.1 - 0.21 11.8 0.1 0.21 11.8 0.0 3.2 4 0 0 4 4 4 0 Predicted membrane protein (DUF2061) TSA PF03249.8 AEO62129.1 - 2.8 6.3 9.2 6.3 5.2 6.4 1.5 1 0 0 1 1 1 0 Type specific antigen PRKCSH PF07915.8 AEO62130.1 - 5.9e-21 75.0 0.1 5.9e-21 75.0 0.1 2.3 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.1 AEO62130.1 - 0.061 12.7 0.0 0.86 9.0 0.0 2.2 2 0 0 2 2 2 0 Glucosidase II beta subunit-like protein DUF718 PF05336.8 AEO62132.1 - 7.3e-36 122.1 0.6 8.6e-36 121.9 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF718) DUF2704 PF10866.3 AEO62132.1 - 0.084 12.2 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2704) stn_TNFRSF12A PF12191.3 AEO62134.1 - 0.054 13.5 4.0 0.089 12.8 2.8 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain SR-25 PF10500.4 AEO62135.1 - 0.11 11.9 3.3 0.21 11.0 2.3 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Suf PF05843.9 AEO62135.1 - 0.24 11.0 1.1 0.45 10.1 0.8 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) AAA PF00004.24 AEO62137.1 - 5.6e-39 133.3 0.0 9.7e-15 54.9 0.0 5.4 6 0 0 6 6 5 4 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 AEO62137.1 - 6.9e-38 130.5 3.8 1e-27 97.2 0.0 6.1 6 0 0 6 6 6 3 AAA domain AAA_12 PF13087.1 AEO62137.1 - 8.4e-35 119.9 0.0 3.8e-34 117.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 AEO62137.1 - 3.4e-20 71.5 12.9 8.4e-09 35.0 0.0 7.1 7 0 0 7 7 6 4 Part of AAA domain AAA_22 PF13401.1 AEO62137.1 - 1.8e-14 54.0 3.9 0.003 17.7 0.1 7.5 5 3 0 5 5 5 3 AAA domain AAA_30 PF13604.1 AEO62137.1 - 3e-14 53.0 10.2 5.5e-06 26.0 0.0 7.0 6 1 0 6 6 6 2 AAA domain AAA_5 PF07728.9 AEO62137.1 - 2.3e-11 43.5 0.7 0.095 12.4 0.0 4.8 4 0 0 4 4 4 4 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 AEO62137.1 - 3.7e-09 36.0 0.2 0.067 12.3 0.0 4.6 4 0 0 4 4 4 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 AEO62137.1 - 6.3e-09 35.4 0.0 0.073 12.4 0.0 4.7 4 0 0 4 4 4 2 IstB-like ATP binding protein AAA_17 PF13207.1 AEO62137.1 - 1e-08 36.0 17.5 0.064 14.0 0.0 5.9 6 0 0 6 6 4 3 AAA domain Torsin PF06309.6 AEO62137.1 - 4e-07 29.9 0.0 0.27 11.1 0.0 4.5 4 0 0 4 4 4 1 Torsin AAA_10 PF12846.2 AEO62137.1 - 7.5e-07 28.8 4.6 0.067 12.6 0.0 6.0 5 1 1 6 6 6 1 AAA-like domain RNA_helicase PF00910.17 AEO62137.1 - 3e-06 27.3 0.1 3.5 7.8 0.0 4.5 4 0 0 4 4 4 1 RNA helicase AAA_24 PF13479.1 AEO62137.1 - 3e-05 23.7 6.3 0.55 9.7 0.1 4.9 5 0 0 5 5 5 1 AAA domain Sigma54_activat PF00158.21 AEO62137.1 - 3.7e-05 23.2 0.1 11 5.4 0.0 5.0 5 0 0 5 5 4 0 Sigma-54 interaction domain AAA_33 PF13671.1 AEO62137.1 - 5.5e-05 23.0 14.5 0.38 10.6 0.0 6.1 6 0 0 6 6 4 2 AAA domain AAA_16 PF13191.1 AEO62137.1 - 0.00037 20.5 36.0 0.033 14.1 0.0 7.9 8 2 1 9 9 6 2 AAA ATPase domain AAA_18 PF13238.1 AEO62137.1 - 0.00059 20.1 13.4 2 8.7 0.1 5.5 6 0 0 6 6 4 2 AAA domain Viral_helicase1 PF01443.13 AEO62137.1 - 0.00065 19.2 8.7 1.3 8.5 0.0 5.1 6 0 0 6 6 5 1 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 AEO62137.1 - 0.00079 18.8 5.0 0.16 11.3 0.0 5.0 4 0 0 4 4 4 1 AAA domain PhoH PF02562.11 AEO62137.1 - 0.00094 18.4 0.1 4.7 6.3 0.0 4.3 4 0 0 4 4 4 0 PhoH-like protein MobB PF03205.9 AEO62137.1 - 0.0011 18.6 0.7 11 5.7 0.0 4.6 4 0 0 4 4 4 0 Molybdopterin guanine dinucleotide synthesis protein B KaiC PF06745.8 AEO62137.1 - 0.0012 18.0 0.5 3.3 6.7 0.0 4.0 4 0 0 4 4 4 1 KaiC AAA_14 PF13173.1 AEO62137.1 - 0.0012 18.7 0.0 4.3 7.2 0.0 4.0 4 0 0 4 4 4 1 AAA domain DUF2075 PF09848.4 AEO62137.1 - 0.0042 16.1 9.7 3.4 6.5 0.0 6.7 6 1 0 6 6 6 1 Uncharacterized conserved protein (DUF2075) AAA_29 PF13555.1 AEO62137.1 - 0.0078 15.7 0.1 24 4.5 0.0 4.0 4 0 0 4 4 4 0 P-loop containing region of AAA domain SRP54 PF00448.17 AEO62137.1 - 0.018 14.5 0.9 0.6 9.5 0.0 3.4 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.10 AEO62137.1 - 0.043 13.5 2.0 54 3.4 0.0 4.3 4 0 0 4 4 4 0 NTPase ResIII PF04851.10 AEO62137.1 - 0.057 13.2 0.0 19 5.0 0.0 3.7 5 0 0 5 5 3 0 Type III restriction enzyme, res subunit NACHT PF05729.7 AEO62137.1 - 0.28 10.8 2.1 70 3.0 0.1 4.3 4 0 0 4 4 4 0 NACHT domain cobW PF02492.14 AEO62137.1 - 0.5 9.7 6.0 3.7 6.9 0.0 4.3 5 0 0 5 5 5 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 AEO62137.1 - 1.3 9.3 8.3 79 3.5 0.1 5.1 5 0 0 5 5 5 0 ABC transporter ADK PF00406.17 AEO62137.1 - 1.7 8.5 5.3 43 3.9 0.1 4.0 4 0 0 4 4 4 0 Adenylate kinase Glyco_hydro_47 PF01532.15 AEO62138.1 - 7.8e-158 525.8 0.0 9.1e-158 525.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Rep_fac_C PF08542.6 AEO62139.1 - 8.4e-20 70.5 0.1 2.2e-19 69.1 0.1 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.24 AEO62139.1 - 4e-16 59.4 0.0 8.7e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 AEO62139.1 - 4.2e-15 55.7 0.0 1e-14 54.5 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 AEO62139.1 - 7.8e-10 38.0 0.0 5.7e-08 31.8 0.0 2.6 1 1 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 AEO62139.1 - 2.8e-07 30.7 0.1 1.3e-06 28.6 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 AEO62139.1 - 1.3e-06 28.5 0.0 0.00012 22.1 0.0 3.1 1 1 0 2 2 2 1 AAA ATPase domain DNA_pol3_delta PF06144.8 AEO62139.1 - 2.6e-06 27.0 0.0 4.7e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_30 PF13604.1 AEO62139.1 - 8e-06 25.5 0.0 1.5e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 AEO62139.1 - 1.4e-05 24.2 0.0 0.00016 20.8 0.0 2.3 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_11 PF13086.1 AEO62139.1 - 1.5e-05 24.7 0.2 0.0004 20.0 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 AEO62139.1 - 1.7e-05 24.4 0.0 4.1e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 AEO62139.1 - 2.5e-05 24.1 0.0 5.3e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 AEO62139.1 - 3.2e-05 22.8 0.0 0.041 12.5 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus PhoH PF02562.11 AEO62139.1 - 0.00016 20.9 0.9 0.54 9.4 0.4 2.8 2 1 1 3 3 3 2 PhoH-like protein AAA_5 PF07728.9 AEO62139.1 - 0.00019 21.1 0.1 0.00062 19.4 0.1 1.9 1 1 1 2 2 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 AEO62139.1 - 0.00026 20.6 0.0 0.00064 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 AEO62139.1 - 0.0003 20.3 0.8 0.0041 16.7 0.1 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 AEO62139.1 - 0.00047 19.2 0.0 0.0007 18.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DUF815 PF05673.8 AEO62139.1 - 0.00079 18.4 0.0 0.0014 17.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_28 PF13521.1 AEO62139.1 - 0.0019 18.1 0.0 0.0037 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 AEO62139.1 - 0.0065 15.9 0.1 0.057 12.9 0.0 2.2 1 1 1 2 2 2 1 DEAD/DEAH box helicase FtsK_SpoIIIE PF01580.13 AEO62139.1 - 0.0081 15.6 0.1 0.92 8.9 0.0 2.5 2 1 1 3 3 3 1 FtsK/SpoIIIE family AAA_10 PF12846.2 AEO62139.1 - 0.011 15.1 0.3 0.89 8.9 0.2 2.5 1 1 0 1 1 1 0 AAA-like domain TK PF00265.13 AEO62139.1 - 0.011 15.2 0.0 0.023 14.2 0.0 1.5 1 0 0 1 1 1 0 Thymidine kinase AAA_25 PF13481.1 AEO62139.1 - 0.012 15.0 0.2 0.047 13.0 0.0 2.0 2 1 1 3 3 2 0 AAA domain ResIII PF04851.10 AEO62139.1 - 0.018 14.8 0.0 0.078 12.8 0.0 2.0 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.12 AEO62139.1 - 0.02 14.2 0.0 0.61 9.4 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_17 PF13207.1 AEO62139.1 - 0.023 15.5 0.0 0.045 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 AEO62139.1 - 0.029 13.5 0.1 0.21 10.6 0.1 2.3 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 AEO62139.1 - 0.033 14.5 0.0 0.093 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 AEO62139.1 - 0.051 13.7 0.0 0.12 12.5 0.0 1.7 1 1 0 1 1 1 0 RNA helicase SNF2_N PF00176.18 AEO62139.1 - 0.059 12.1 0.0 0.57 8.9 0.0 2.1 1 1 0 1 1 1 0 SNF2 family N-terminal domain ABC_tran PF00005.22 AEO62139.1 - 0.085 13.1 0.0 0.18 12.0 0.0 1.6 1 1 0 1 1 1 0 ABC transporter Arch_ATPase PF01637.13 AEO62139.1 - 0.1 12.2 0.0 0.3 10.7 0.0 1.7 1 1 1 2 2 2 0 Archaeal ATPase AAA_33 PF13671.1 AEO62139.1 - 0.15 11.9 0.2 0.39 10.5 0.1 1.8 2 1 0 2 2 1 0 AAA domain adh_short PF00106.20 AEO62140.1 - 7.5e-06 25.9 0.5 2.7e-05 24.1 0.4 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 AEO62140.1 - 0.13 11.9 0.2 0.27 10.8 0.0 1.6 2 0 0 2 2 2 0 KR domain Microtub_assoc PF07989.6 AEO62141.1 - 7.5e-05 22.4 4.0 0.00015 21.4 2.8 1.5 1 0 0 1 1 1 1 Microtubule associated Asp PF00026.18 AEO62142.1 - 1.3e-51 175.7 0.0 1.3e-51 175.7 0.0 1.7 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 AEO62142.1 - 2.1e-06 27.7 0.1 2.1e-06 27.7 0.1 2.9 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 AEO62142.1 - 0.00053 19.5 0.0 0.015 14.8 0.0 2.6 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal RuBisCO_large_N PF02788.11 AEO62143.1 - 0.056 13.1 0.3 0.086 12.5 0.2 1.3 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, N-terminal domain Acetyltransf_4 PF13420.1 AEO62144.1 - 2.4e-23 82.7 0.0 7.9e-23 81.1 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 AEO62144.1 - 1.3e-10 41.1 0.0 2e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 AEO62144.1 - 4.7e-07 29.9 0.0 1.6e-06 28.2 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 AEO62144.1 - 0.00011 21.9 0.0 0.00018 21.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 AEO62144.1 - 0.00034 20.7 0.0 0.00051 20.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 AEO62144.1 - 0.0007 19.6 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 AEO62144.1 - 0.018 14.9 0.0 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 AEO62144.1 - 0.091 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase MFS_1 PF07690.11 AEO62145.1 - 4.8e-37 127.4 29.7 5.2e-37 127.3 20.2 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily ATG22 PF11700.3 AEO62145.1 - 0.00013 20.6 3.7 0.017 13.6 0.2 3.1 2 1 1 3 3 3 2 Vacuole effluxer Atg22 like DUF2142 PF09913.4 AEO62145.1 - 0.014 14.1 12.0 0.078 11.6 6.8 3.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2142) DUF829 PF05705.9 AEO62146.1 - 2.5e-29 102.6 0.0 6.4e-20 71.8 0.1 2.5 2 1 0 2 2 2 2 Eukaryotic protein of unknown function (DUF829) DUF508 PF04370.7 AEO62146.1 - 2.7 7.5 12.1 5 6.7 8.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF508) KH_1 PF00013.24 AEO62147.1 - 2.2e-44 148.8 11.8 1e-15 57.1 1.3 3.5 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 AEO62147.1 - 2.5e-31 106.7 17.7 9.8e-11 41.0 1.3 4.1 4 0 0 4 4 4 3 KH domain KH_2 PF07650.12 AEO62147.1 - 2e-13 49.6 1.1 0.0017 17.8 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 AEO62147.1 - 6e-09 35.4 4.6 0.058 13.0 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 AEO62147.1 - 0.0002 21.0 2.5 0.49 10.2 0.1 3.4 3 0 0 3 3 3 2 NusA-like KH domain SLS PF14611.1 AEO62147.1 - 0.042 13.2 0.0 13 5.0 0.0 3.0 3 0 0 3 3 3 0 Mitochondrial inner-membrane-bound regulator Asp PF00026.18 AEO62148.1 - 6.2e-43 147.2 0.3 1e-42 146.5 0.2 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 AEO62148.1 - 3e-06 27.6 0.1 2.2 8.8 0.0 3.4 3 0 0 3 3 3 3 Aspartyl protease TAXi_C PF14541.1 AEO62148.1 - 3.8e-06 26.5 0.2 5e-05 22.9 0.0 2.7 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 AEO62148.1 - 0.0021 17.8 0.0 1.3 8.9 0.0 2.6 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease 6PF2K PF01591.13 AEO62149.1 - 7.1e-80 267.2 0.0 9.7e-80 266.8 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 AEO62149.1 - 3.6e-33 114.8 0.1 8.6e-33 113.6 0.0 1.7 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 AEO62149.1 - 4.3e-09 36.3 0.1 8.2e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 AEO62149.1 - 0.0015 17.7 0.0 0.0023 17.1 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 AEO62149.1 - 0.0021 18.8 0.5 0.024 15.4 0.0 2.6 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 AEO62149.1 - 0.029 13.4 0.0 0.13 11.3 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin DUF3157 PF11355.3 AEO62149.1 - 0.078 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3157) DEAD PF00270.24 AEO62151.1 - 4.8e-43 146.5 0.1 1.6e-42 144.8 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.1 AEO62151.1 - 3.7e-22 77.6 0.2 3.7e-22 77.6 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 AEO62151.1 - 1.7e-20 72.6 0.0 5e-20 71.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 AEO62151.1 - 0.083 11.9 4.5 6.2 5.8 1.6 2.4 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Spore_coat_CotO PF14153.1 AEO62151.1 - 1.4 8.3 5.0 2.4 7.5 3.4 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Herpes_LMP1 PF05297.6 AEO62151.1 - 3.9 6.3 6.3 5.3 5.8 4.4 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Daxx PF03344.10 AEO62151.1 - 5.3 5.4 15.0 7.2 4.9 10.4 1.1 1 0 0 1 1 1 0 Daxx Family HNH_2 PF13391.1 AEO62152.1 - 5.7e-13 48.4 0.0 1.6e-12 46.9 0.0 1.8 2 0 0 2 2 2 1 HNH endonuclease SKG6 PF08693.5 AEO62153.1 - 0.0027 16.9 0.7 0.0027 16.9 0.5 2.2 2 0 0 2 2 2 1 Transmembrane alpha-helix domain YbaJ PF10757.4 AEO62153.1 - 0.011 15.8 1.2 0.51 10.4 0.1 2.9 3 0 0 3 3 3 0 Biofilm formation regulator YbaJ Baculo_PEP_C PF04513.7 AEO62153.1 - 0.25 11.1 18.6 0.19 11.5 0.9 4.2 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Trp_syntA PF00290.15 AEO62154.1 - 2.4e-95 317.9 0.1 5e-95 316.9 0.0 1.5 2 0 0 2 2 2 1 Tryptophan synthase alpha chain PALP PF00291.20 AEO62154.1 - 1e-42 146.4 0.6 1.8e-42 145.6 0.4 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PcrB PF01884.12 AEO62154.1 - 0.0012 18.1 0.2 0.31 10.2 0.1 2.5 2 0 0 2 2 2 2 PcrB family Ribosomal_L28 PF00830.14 AEO62155.1 - 1.2e-19 69.8 0.9 2.4e-19 68.9 0.7 1.5 1 0 0 1 1 1 1 Ribosomal L28 family SSP160 PF06933.6 AEO62155.1 - 0.5 8.2 4.4 0.6 8.0 3.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.3 AEO62155.1 - 6 6.6 8.6 9.4 6.0 5.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) HAUS4 PF14735.1 AEO62156.1 - 0.05 12.8 0.5 0.5 9.6 0.4 2.3 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 4 TBCA PF02970.11 AEO62156.1 - 0.38 10.8 5.7 4.2 7.5 0.3 3.0 2 1 1 3 3 3 0 Tubulin binding cofactor A Aminotran_1_2 PF00155.16 AEO62157.1 - 1e-92 310.9 0.0 1.2e-92 310.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II PolC_DP2 PF03833.8 AEO62157.1 - 0.071 10.7 0.0 0.096 10.3 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 ADH_N PF08240.7 AEO62158.1 - 5.9e-24 83.9 2.5 9.3e-24 83.2 1.7 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 AEO62158.1 - 1e-20 73.6 0.0 1.5e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 AEO62158.1 - 0.0092 15.1 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 AEO62158.1 - 0.019 15.0 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF4241 PF14025.1 AEO62158.1 - 0.033 13.9 0.0 0.071 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4241) Amb_V_allergen PF03913.8 AEO62158.1 - 0.077 12.7 1.0 0.17 11.6 0.7 1.5 1 0 0 1 1 1 0 Amb V Allergen F-box PF00646.28 AEO62159.1 - 1.2e-06 27.9 0.3 3.4e-06 26.5 0.2 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 AEO62159.1 - 0.00044 19.9 0.1 0.0016 18.1 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 AEO62159.1 - 0.15 11.8 2.5 1.6 8.4 1.7 2.3 1 1 0 1 1 1 0 F-box-like domain MFS_1 PF07690.11 AEO62160.1 - 6.6e-13 48.1 31.7 6.1e-10 38.3 15.5 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Cellulase PF00150.13 AEO62161.1 - 4.6e-16 58.8 5.5 6.6e-16 58.3 3.8 1.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.10 AEO62161.1 - 7.4e-05 22.0 0.1 0.0005 19.3 0.0 2.4 3 1 0 3 3 3 1 Beta-galactosidase Glyco_hydro_2_C PF02836.12 AEO62161.1 - 0.0001 21.3 0.0 0.0004 19.3 0.0 2.0 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase-like PF12876.2 AEO62161.1 - 0.00012 22.4 0.0 0.00034 21.0 0.0 1.8 1 1 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_10 PF00331.15 AEO62161.1 - 0.035 13.1 0.0 0.061 12.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 10 Chitin_bind_3 PF03067.10 AEO62162.1 - 2.2e-09 37.8 0.1 1.4e-06 28.7 0.0 2.2 1 1 0 2 2 2 2 Chitin binding domain Sugar_tr PF00083.19 AEO62163.1 - 4.2e-76 256.3 15.6 2.5e-72 243.9 7.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 AEO62163.1 - 9.3e-07 27.8 37.0 0.00013 20.8 16.2 2.8 1 1 2 3 3 3 2 Major Facilitator Superfamily HET PF06985.6 AEO62166.1 - 2.2e-12 47.3 0.9 4.5e-12 46.3 0.5 1.4 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET)